title: Distribution of quorum-sensing genes in the Burkholderia cepacia complex.
abstract: The distribution of quorum-sensing genes among strains from seven genomovars of the Burkholderia cepacia complex was examined by PCR. cepR and cepI were amplified from B. cepacia genomovars I and III, B. stabilis, and B. vietnamiensis. cepR was also amplified from B. multivorans and B. cepacia genomovar VI. bviIR were amplified from B. vietnamiensis. All genomovars produced N-octanoyl-L-homoserine lactone and N-hexanoyl-L-homoserine lactone. B. vietnamiensis and B. cepacia genomovar VII produced additional N-acyl-L-homoserine lactones.
authors.affiliation: Department of Microbiology and Infectious Diseases, University of Calgary Health Sciences Center, Calgary, Alberta, Canada T2N 4N1.
authors.forename: E
authors.initials: E
authors.lastname: Lutter
authors.forename: S
authors.initials: S
authors.lastname: Lewenza
authors.forename: J J
authors.initials: JJ
authors.lastname: Dennis
authors.forename: M B
authors.initials: MB
authors.lastname: Visser
authors.forename: P A
authors.initials: PA
authors.lastname: Sokol
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000096:biosynthesis; D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D019117:Burkholderia / Q000235:genetics; D016956:Burkholderia cepacia / Q000235:genetics*; D005798:Genes, Bacterial; D006714:Homoserine / Q000031:analogs & derivatives / Q000096:biosynthesis; D007783:Lactones; D008025:Ligases; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid
chemical_list: D001426:Bacterial Proteins; C117246:CepR protein, Burkholderia; D007783:Lactones; C104908:N-hexanoyl-L-homoserine lactone; C091088:N-octanoylhomoserine lactone; C088386:homoserine lactone; D006714:Homoserine; D008025:Ligases; C449816:N-acylhomoserine lactone synthase; D015107:4-Butyrolactone