title: Renal Transport of Urate in Humans.
abstract: The theory of the "four-component model" of urate excretion in humans is reevaluated, considering that a decrease in urate excretion induced by drugs like pyrazinamide or by endogenous compounds like lactate and ketone bodies might be a result of stimulation of urate reabsorption and not, as previously considered, of inhibition of urate secretion.
authors.affiliation: Institut de Pharmacologie et Toxicologie, Bugnon 27, CH1005 Lausanne, Switzerland.
authors.forename: Françoise
authors.initials: F
authors.lastname: Roch-Ramel
authors.forename: Barbara
authors.initials: B
authors.lastname: Guisan