title: Splenic abscess--a changing trend in treatment.
abstract: Fifteen patients with splenic abscesses were evaluated between 1985 and 1995. The most common predisposing factors were remote infection, diabetes mellitus and heart disease. Common clinical presentations included leucocytosis, fever, left upper quadrant abdominal pain and left pleural effusion. Four patients with splenic abscesses smaller than 4 cm in diameter were treated with antibiotics alone, and 1 in this treatment group died. Among the 10 patients with splenic abscesses larger than 4 cm in diameter receiving percutaneous drainage, 9 (90%) were successfully cured, including 8 with unilocular abscesses and 1 with multilocular abscesses. Two patients underwent splenectomy. In conclusion, percutaneous drainage using ultrasound or computed tomography guidance may be recommended as the treatment of choice for splenic abscess larger than 4 cm in diameter. Antibiotics alone may sometimes be considered for splenic abscesses smaller than 4 cm in diameter. Splenectomy is reserved for those cases where medical treatment has failed.
authors.affiliation: Department of Surgery, Veterans General Hospital, Taipei, National Yang Ming University, Taipei, Taiwan, Republic of China.
authors.forename: K Y
authors.initials: KY
authors.lastname: Liu
authors.forename: Y M
authors.initials: YM
authors.lastname: Shyr
authors.forename: C H
authors.initials: CH
authors.lastname: Su
authors.forename: C W
authors.initials: CW
authors.lastname: Wu
authors.forename: L Y
authors.initials: LY
authors.lastname: Lee
authors.forename: W Y
authors.initials: WY
authors.lastname: Lui
mesh_terms: D000038:Abscess / Q000453:epidemiology / Q000628:therapy*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015984:Causality; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013156:Splenectomy; D013158:Splenic Diseases / Q000453:epidemiology / Q000628:therapy*; D013624:Taiwan / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents