Cell biology. Protein clumps hijack cell's clearance system.
Helmuth
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D000818:Animals; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D000071058:Huntingtin Protein; D009097:Multienzyme Complexes / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000378:metabolism; D019636:Neurodegenerative Diseases / Q000378:metabolism*; D009687:Nuclear Proteins / Q000737:chemistry / Q000378:metabolism; D046988:Proteasome Endopeptidase Complex; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*; D014452:Ubiquitins / Q000378:metabolism*
C505032:CFTR protein, human; C086055:HTT protein, human; D000071058:Huntingtin Protein; D009097:Multienzyme Complexes; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D011506:Proteins; D014452:Ubiquitins; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex