Implications of mouse genotype for phenotype.
Genetic engineering of inbred mice offers the capability to separate interactions of multiple genes that control host resistance to pathogens. An understanding of the negative impact that genetic variability of mouse substrains can have on data is necessary for the design of experiments to dissect out complicated gene interactions.
Hickman-Davis
J M
JM
Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35249-0006, USA.
D000818:Animals; D001424:Bacterial Infections / Q000235:genetics* / Q000276:immunology*; D004195:Disease Models, Animal; D005838:Genotype; D051379:Mice; D008822:Mice, Transgenic; D010641:Phenotype