Pericardial mesothelioma following mantle field radiotherapy.
A 49-year-old female was referred with recurrent pericardial effusion following mantle field radiotherapy for Hodgkin s lymphoma. She underwent video-assisted thoracoscopy and resection of a pericardial window. Intraoperatively she suffered a cardiac arrest and subsequently died in the early postoperative period despite maximal therapy. Pathological examination revealed extensive myocardial fibrosis and multiple nodules of pericardial mesothelioma. The latter has hitherto not been recognised following mediastinal radiation. The cardiac complications of mantle field radiotherapy are discussed.
Velissaris
T J
TJ
Departments of Cardiothoracic Surgery, Southampton General Hospital, Southampton, UK. theovelissaris@hotmail.com
Tang
A T
AT
Millward-Sadler
G H
GH
Morgan
J M
JM
Tsang
G M
GM
D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000473:pathology / Q000601:surgery*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008654:Mesothelioma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000601:surgery*; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000601:surgery*; D010490:Pericardial Effusion / Q000473:pathology / Q000601:surgery; D020519:Pericardiocentesis; D010496:Pericardium / Q000473:pathology / Q000528:radiation effects* / Q000601:surgery; D020775:Thoracic Surgery, Video-Assisted