Cimetidine-induced dystonic reaction.
A 39-year-old woman presented to the Emergency Department complaining of nausea and vomiting. The patient was given intravenous cimetidine for epigastric pain and subsequently developed a dystonic reaction. Administration of cimetidine, an H2 receptor antagonist, is an uncommon cause of dystonic reaction. We discuss the pathophysiology, diagnosis, and treatment.
Peiris
R S
RS
Department of Emergency Medicine, St. Barnabus Hospital, Bronx, New York, USA.
Peckler
B F
BF
D000328:Adult; D000897:Anti-Ulcer Agents / Q000009:adverse effects*; D018680:Cholinergic Antagonists; D002927:Cimetidine / Q000009:adverse effects*; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy / Q000209:etiology*; D004421:Dystonia / Q000139:chemically induced* / Q000188:drug therapy; D004632:Emergency Medical Services; D005260:Female; D006635:Histamine H2 Antagonists / Q000009:adverse effects*; D006801:Humans
D000897:Anti-Ulcer Agents; D018680:Cholinergic Antagonists; D006635:Histamine H2 Antagonists; D002927:Cimetidine