title: Fractal analysis of bone X-ray tomographic microscopy projections.
abstract: Fractal analysis of bone X-ray images has received much interest recently for the diagnosis of bone disease. In this paper, we propose a fractal analysis of bone X-ray tomographic microscopy (XTM) projections. The aim of the study is to establish whether or not there is a correlation between three-dimensional (3-D) trabecular changes and two-dimensional (2-D) fractal descriptors. Using a highly collimated beam, 3-D bone X-ray tomographic images were obtained. Trabecular bone loss was simulated using a mathematical morphology method. Then, 2-D projections were generated in each of the three orthogonal directions. Finally, the model of fractional Brownian motion (fBm) was used on bone XTM 2-D projections to characterize changes in bone structure that occur during disease, such a simulation of bone loss. Results indicate that fBm is a robust texture model allowing quantification of simulations of trabecular bone changes.
authors.affiliation: Laboratory of Electronics, Signals and Images, University of Orleans, France. Rachid.Jennane@univ-orleans.fr
authors.forename: R
authors.initials: R
authors.lastname: Jennane
authors.forename: W J
authors.initials: WJ
authors.lastname: Ohley
authors.forename: S
authors.initials: S
authors.lastname: Majumdar
authors.forename: G
authors.initials: G
authors.lastname: Lemineur
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000473:pathology*; D003198:Computer Simulation; D017709:Fractals; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008853:Microscopy / Q000295:instrumentation / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*