title: Emergency surgery for obstructing colorectal cancers: a comparison between right-sided and left-sided lesions.
abstract: BACKGROUND
  Fifteen to twenty percent of patients with primary colorectal cancers present with intestinal obstruction. Traditionally, different approaches have been used in the management of right-sided and left-sided colonic obstruction. Recently, single-stage resection with primary anastomosis in left colonic obstruction has been shown to have good results. The objective of this study was to compare the operative results of patients who had emergency operations for right-sided and left-sided obstructions from primary colorectal cancers.
  
  
  METHODS
  This is a retrospective study including 243 patients who underwent emergency operations for obstructing colorectal cancers from 1989 to 1997. Primary resection of the tumor-bearing segment followed by primary anastomosis was attempted when the conditions were feasible. The operative results of patients with right-sided tumors were compared with those of patients with left-sided tumors.
  
  
  RESULTS
  One hundred seven patients had obstruction at or proximal to the splenic flexure (right-sided lesions), and 136 had lesions distal to the splenic flexure (left-sided lesions). The primary resection rate was 91.8%. Of the 223 patients with primary resection, primary anastomosis was possible in 197 patients. Among the 101 primary anastomoses in patients with left-sided obstruction, segmental resection with on-table lavage was performed in 75 patients and subtotal colectomy was performed in 26. The overall operative mortality rate was 9.4%, although that of the patients with primary resection and anastomosis was 8.1%. The anastomotic leakage rate for those with primary resection and anastomosis was 6.1%. There were no differences in the mortality or leakage rates between patients with right-sided and left-sided lesions (mortality: 7.3% versus 8.9%, p = 0.79; leakage: 5.2% versus 6.9%, p = 0.77). Colocolonic anastomosis did not show a significant difference in leakage rate when compared with ileocolonic anastomosis (6.1% versus 6.0%, p = 1.0).
  
  
  CONCLUSIONS
  This study showed that primary resection and anastomosis for left-sided malignant obstruction, either by segmental resection with on-table lavage or subtotal colectomy, was not more hazardous than primary anastomosis for right-sided obstruction. The single-stage procedure should be the objective for the treatment of patients with obstructing colorectal cancers, except when patients are hemodynamically unstable during surgery or when the condition of the bowel is not optimal for primary anastomosis.
authors.affiliation: Department of Surgery, Queen Mary Hospital, University of Hong Kong Medical Centre, Hong Kong.
authors.forename: Y M
authors.initials: YM
authors.lastname: Lee
authors.forename: W L
authors.initials: WL
authors.lastname: Law
authors.forename: K W
authors.initials: KW
authors.lastname: Chu
authors.forename: R T
authors.initials: RT
authors.lastname: Poon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D003082:Colectomy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D003108:Colonic Diseases / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000150:complications* / Q000401:mortality / Q000473:pathology; D004630:Emergencies; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D007507:Therapeutic Irrigation / Q000379:methods; D016896:Treatment Outcome