title: Adrenocortical carcinoma metastatic to the orbit.
abstract: OBJECTIVE
  To describe the clinical course and histopathologic features of a patient with adrenocortical carcinoma metastatic to the orbit.
  
  
  METHODS
  Case report and literature review.
  
  
  RESULTS
  A 24-year-old man first came to medical attention because of symptoms referable to a 4.47-kg, nonfunctioning carcinoma of the left adrenal cortex. Several metastases ensued, including a large tumor to the right superior lateral bony orbit with extension to the brain, temporalis fossa, and orbit proper. The tumor was resected with the use of a combined neurosurgical, ophthalmic, and craniofacial approach. The patient died of widespread metastatic disease 15 months after the orbital operation.
  
  
  CONCLUSIONS
  Metastasis to the orbit from adrenocortical carcinoma is rare. Surgical resection is the treatment of choice, with adjunctive radiation therapy and chemotherapy in some cases. The prognosis is poor.
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: G B
authors.initials: GB
authors.lastname: Bartley
authors.forename: R J
authors.initials: RJ
authors.lastname: Campbell
authors.forename: D R
authors.initials: DR
authors.lastname: Salomão
authors.forename: E A
authors.initials: EA
authors.lastname: Bradley
authors.forename: W R
authors.initials: WR
authors.lastname: Marsh
authors.forename: U
authors.initials: U
authors.lastname: Bite
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000473:pathology* / Q000601:surgery; D000315:Adrenalectomy; D018268:Adrenocortical Carcinoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D000328:Adult; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D014057:Tomography, X-Ray Computed