title: The junction-resolving enzymes.
abstract: Junction-resolving enzymes are ubiquitous nucleases that are important for DNA repair and recombination and act on DNA molecules containing branch points, especially four-way junctions. They show a pronounced selectivity for the structure of the DNA substrate but, despite its importance, the structural selectivity is not well understood. This poses an intriguing challenge in molecular recognition on a relatively large scale.
authors.affiliation: CRC Nucleic Acid Structure Research Group, Department of Biochemistry, University of Dundee, Dundee DD1 5EH, UK. dmjlilley@bad.dundee.ac.uk
authors.forename: D M
authors.initials: DM
authors.lastname: Lilley
authors.forename: M F
authors.initials: MF
authors.lastname: White
mesh_terms: D000818:Animals; D004260:DNA Repair; D004706:Endodeoxyribonucleases; D006801:Humans; D011995:Recombination, Genetic
chemical_list: D004706:Endodeoxyribonucleases