Expanding drug resistance through integron acquisition by IncFI plasmids of Salmonella enterica Typhimurium.
We conducted a 30-year retrospective analysis of IncFI plasmids from Salmonella enterica serotype Typhimurium. These plasmids have been associated with the emergence of epidemic clones of multidrug-resistant Salmonella. Molecular and genetic evidence indicates that IncFI plasmids are evolving through sequential acquisition of integrons carrying different arrays of antibiotic- resistance genes.
Carattoli
A
A
Istituto Superiore di Sanità, Rome, Italy. alecara@iss.it
Villa
L
L
Pezzella
C
C
Bordi
E
E
Visca
P
P
D004352:Drug Resistance, Microbial; D010957:Plasmids; D012189:Retrospective Studies; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics*