title: Are women with premenstrual dysphoric disorder prone to osteoporosis?
abstract: OBJECTIVE
  The objective of this study was to examine whether bone mineral density (BMD) is reduced in women with premenstrual dysphoric disorder (PMDD).
  
  
  METHODS
  Thirty-eight healthy women participated: 20 with prospectively confirmed PMDD and 18 without PMDD. Bone mass was measured using dual-energy x-ray absorptiometry at three sites: lumbar spine anteroposterior, lumber spine lateral, and femoral neck. Results from the PMDD and control groups were compared with each other and with age- and sex-matched normative data.
  
  
  RESULTS
  The BMD of both groups was as expected for their age and sex, and groups did not differ in BMD or Z scores for any of the bone sites studied.
  
  
  CONCLUSIONS
  If women with PMDD are at an increased risk of developing osteoporosis, this risk is not manifested in their BMD.
authors.affiliation: BioBehavioral Program, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14215, USA. urielh@acsu.buffalo.edu
authors.forename: U
authors.initials: U
authors.lastname: Halbreich
authors.forename: L S
authors.initials: LS
authors.lastname: Kahn
mesh_terms: D000328:Adult; D015519:Bone Density / Q000502:physiology; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology* / Q000523:psychology*; D011293:Premenstrual Syndrome / Q000523:psychology*; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors