title: Olanzapine: another psychotropic?
abstract: Olanzapine is a favorable drug with a potential treatment of delirium, psychotic depression, mood disorders and nausea with a single drug in advanced cancer patients. Additional benefits include weight gain. The medication has few drug interactions, a narrow therapeutic window and high drug cost, which is a disadvantage compounded by a single route of administration. Reduced hospitalizations, at least in the psychiatric patient, may offset the drug cost.
authors.affiliation: Harry R. Horvitz Center for Palliative Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
authors.forename: M P
authors.initials: MP
authors.lastname: Davis
authors.forename: E D
authors.initials: ED
authors.lastname: Dickerson
mesh_terms: D000284:Administration, Oral; D014150:Antipsychotic Agents / Q000191:economics / Q000494:pharmacology / Q000627:therapeutic use*; D001569:Benzodiazepines; D016527:Drug Costs; D004347:Drug Interactions; D017051:Hospice Care / Q000379:methods*; D006801:Humans; D000077152:Olanzapine; D018579:Patient Selection; D010890:Pirenzepine / Q000031:analogs & derivatives* / Q000191:economics / Q000494:pharmacology / Q000627:therapeutic use*; D017367:Selective Serotonin Reuptake Inhibitors / Q000191:economics / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine; D010890:Pirenzepine; D017367:Selective Serotonin Reuptake Inhibitors