title: Effects of antisocial or social attitudes on neurobiological functions.
abstract: Antisocial personality disorder is characterized by triats like a failure to conform to social norms, impulsivity, hostility, irritability and aggressiveness, recklessness, irresponsibility, criminality, a lack of guilt or remorse, and deceitfulness. A large number of investigations revealed that there is evidence for a neurobiological underpinning of antisocial behavior. The precise nature and causal aspects of the relationship between neurobiological abnormalities and antisocial behavior is still unknown. There is, however, some evidence that some antisocial patients are able to influence their neurobiological functions, which are related to sensation seeking, aggressiveness, impulsivity, criminality and a lack of fear (associated with an inability to learn from experiences). The author hypothesizes that a reduction of antisocial behavior/attitude, may consequently result in normalization of neurobiological functions, which are linked to specific attitudes and behavioral dimensions.
authors.affiliation: W. Khan Institute of Theoretical Psychiatry and Neuroscience, Utrecht, The Netherlands.
authors.forename: W H
authors.initials: WH
authors.lastname: Martens
mesh_terms: D000987:Antisocial Personality Disorder / Q000235:genetics / Q000378:metabolism / Q000503:physiopathology*; D001290:Attitude; D001921:Brain / Q000502:physiology / Q000503:physiopathology; D006801:Humans