title: Alcohol and cancer.
abstract: This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Helmut K. Seitz and Shohei Matsuzaki. The presentations were (1) Alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 genotype and cancer risk for upper aerodigestive tract in Japanese alcoholics, by Akira Yokoyama; (2) The role of acetaldehyde in alcohol-associated carcinogenesis, by Nils Homann; (3) High salivary acetaldehyde levels after a moderate dose of alcohol in ALDH2-deficient subjects, by Satu Väkeväinen; (4) Alcohol and vitamin A interactions, by Xian Dong Wang; and (5) Alcohol and colorectal cancer, by Helmut K. Seitz.
authors.affiliation: Laboratory of Alcohol Research, Liver Disease and Nutrition, and Department of Medicine, Salem Medical Center, Heidelberg, Germany. Helmut_Karl.Seitz@urz.uni-heidelberg.de
authors.forename: H K
authors.initials: HK
authors.lastname: Seitz
authors.forename: S
authors.initials: S
authors.lastname: Matsuzaki
authors.forename: A
authors.initials: A
authors.lastname: Yokoyama
authors.forename: N
authors.initials: N
authors.lastname: Homann
authors.forename: S
authors.initials: S
authors.lastname: Väkeväinen
authors.forename: X D
authors.initials: XD
authors.lastname: Wang
mesh_terms: D000079:Acetaldehyde / Q000378:metabolism*; D000426:Alcohol Dehydrogenase / Q000235:genetics / Q000378:metabolism; D000437:Alcoholism / Q000235:genetics / Q000378:metabolism*; D000444:Aldehyde Dehydrogenase / Q000235:genetics / Q000378:metabolism*; D000071396:Aldehyde Dehydrogenase, Mitochondrial; D000818:Animals; D002492:Central Nervous System Depressants / Q000378:metabolism / Q000494:pharmacology; D015179:Colorectal Neoplasms / Q000209:etiology / Q000378:metabolism*; D019392:Cytochrome P-450 CYP2E1 / Q000187:drug effects / Q000378:metabolism; D000431:Ethanol / Q000378:metabolism / Q000494:pharmacology; D006258:Head and Neck Neoplasms / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics; D012307:Risk Factors; D012463:Saliva / Q000187:drug effects / Q000378:metabolism; D014801:Vitamin A / Q000378:metabolism*
chemical_list: D002492:Central Nervous System Depressants; D014801:Vitamin A; D000431:Ethanol; D000426:Alcohol Dehydrogenase; D019392:Cytochrome P-450 CYP2E1; C096127:ALDH2 protein, human; D000444:Aldehyde Dehydrogenase; D000071396:Aldehyde Dehydrogenase, Mitochondrial; D000079:Acetaldehyde