VRL-1 immunoreactivity in the rat cranial autonomic ganglia.
Immunohistochemistry for VRL-1, a newly cloned capsaicin-receptor homologue, was performed on the rat cranial autonomic ganglia. The immunoreactivity (ir) was detected in the majority of neurones in the pterygopalatine (66%) and submandibular ganglia (68%). In the tongue and carotid body, parasympathetic neurones contained VRL-I ir. In the superior cervical ganglion, only 2% of postganglionic sympathetic neurones showed the immunoreactivity. VRL-1-ir nerve endings could not be detected in their peripheral tissues. These findings may suggest that VRL-1 has functions within neuronal cell bodies of the cranial autonomic ganglia.
Ichikawa
H
H
Second Department of Oral Anatomy and Biodental Research Center, Okayama University Dental School, Japan.
Sugimoto
T
T
D000818:Animals; D001921:Brain / Q000378:metabolism*; D005725:Ganglia, Autonomic / Q000378:metabolism*; D005726:Ganglia, Parasympathetic / Q000378:metabolism; D007150:Immunohistochemistry; D008297:Male; D010159:Palate / Q000294:innervation; D011626:Pterygoid Muscles / Q000294:innervation; D051381:Rats; D017207:Rats, Sprague-Dawley; D011955:Receptors, Drug / Q000378:metabolism*; D050916:TRPV Cation Channels; D014018:Tissue Distribution
D011955:Receptors, Drug; D050916:TRPV Cation Channels; C494484:TRPV1 receptor