title: In vitro development of resistance to newer fluoroquinolones in Streptococcus pneumoniae isolates with reduced susceptibility to ciprofloxacin.
authors.affiliation: Institute for Medical Microbiology and Virology, Heinrich-Heine Universität Düsseldorf, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Mayer
authors.forename: M
authors.initials: M
authors.lastname: Boos
authors.forename: K
authors.initials: K
authors.lastname: Köhrer
authors.forename: A C
authors.initials: AC
authors.lastname: Fluit
authors.forename: F J
authors.initials: FJ
authors.lastname: Schmitz
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D027081:DNA Gyrase; D027101:DNA Topoisomerase IV; D004250:DNA Topoisomerases, Type II / Q000378:metabolism; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000201:enzymology
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D027101:DNA Topoisomerase IV; D027081:DNA Gyrase; D004250:DNA Topoisomerases, Type II