title: Effect of Laticauda semifasciata (sea snake) venom on chloride transport across the frog skin.
abstract: Addition of Laticauda semifasciata venom to the outside bathing solution of isolated frog skin elicited sustained increases in transepithelial potential difference, short-circuit current and transepithelial electrical resistance. The Laticauda semifasciata venom-induced short-circuit is carried by a net active Na+ transfer from the outside to the inside bathing solution while the increase in transepithelial resistance is accounted for by a decrease in the outside to inside Cl- flux.
authors.affiliation: Department of Physiology, College of Medicine, University of Florida, Gainesville, FL 32610, USA. gag@phys.med.ufl.edu
authors.forename: G A
authors.initials: GA
authors.lastname: Gerencser
authors.forename: K M
authors.initials: KM
authors.lastname: Cornette
mesh_terms: D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D002712:Chlorides / Q000378:metabolism*; D004546:Elapid Venoms / Q000494:pharmacology*; D066298:In Vitro Techniques; D011868:Radioisotopes; D011892:Rana catesbeiana; D012867:Skin / Q000187:drug effects / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism
chemical_list: D002712:Chlorides; D004546:Elapid Venoms; D011868:Radioisotopes; D012964:Sodium