[Analysis of DNA status in bone marrow cells of mice internally irradiated with 90Sr ].
The response of bone marrow cells of CBA mice injected with 22.2, 222 and 592 kBq/animal to additional gamma-irradiation (3 Gy) for testing purposes was evaluated using SCG (Comet assay). A decrease in induction of DNA damage right after additional gamma-irradiation was determined. It correlated with bone marrow cell quantity and the tail length before additional gamma-irradiation. The results support the suggestion about the activation of DNA repair in bone marrow cells under exposure to 90Sr in vivo.
Priakhin
E A
EA
Ural Research Center for Radiation Medicine, Chelyabinsk, 454076 Russia. pryakhin@urcrm.chel.su
Korytnyĭ
V S
VS
Akleev
A V
AV
Krupitskaia
L I
LI
Anisimova
G G
GG
Tolstykh
E I
EI
Triapitsyna
G A
GA
D000818:Animals; D001854:Bone Marrow Cells / Q000528:radiation effects*; D020552:Comet Assay; D004249:DNA Damage / Q000528:radiation effects*; D004260:DNA Repair; D005720:Gamma Rays; D051379:Mice; D008808:Mice, Inbred CBA; D013326:Strontium Radioisotopes
D013326:Strontium Radioisotopes