Plasmodium falciparum and hepatitis E virus co-infection in fulminant hepatic failure.
Acute hepatitis E and falciparum malaria can each present with fulminant hepatic failure and are common in tropical countries. However, co-existence of these two conditions has not been reported. We report a 20-year-old girl who presented with fever and altered sensorium. Peripheral smear was positive for Plasmodium falciparum, and IgM anti-HEV was positive. She died despite antimalarial drugs and supportive management. Postmortem liver tissue showed changes suggestive of acute viral hepatitis.
Ghoshal
U C
UC
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow. ghoshal@sgpgi.ac.in
Somani
S
S
Chetri
K
K
Akhtar
P
P
Aggarwal
R
R
Naik
S R
SR
D000208:Acute Disease; D000328:Adult; D000818:Animals; D017809:Fatal Outcome; D005260:Female; D016751:Hepatitis E / Q000150:complications*; D016752:Hepatitis E virus / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D017093:Liver Failure / Q000469:parasitology* / Q000821:virology*; D016778:Malaria, Falciparum / Q000150:complications*; D010963:Plasmodium falciparum / Q000302:isolation & purification
D007075:Immunoglobulin M