Effects of Th-2 type cytokines on human airway epithelial cells: interleukins-4, -5, and -13.
Proliferation and death of airway epithelial cells may be of importance in the pathogenesis of asthma. T-helper (Th)-2 response interleukins (IL)-4, -5, and -13 have the ability to induce proliferation of airway epithelial cells.
Relova
A J
AJ
Department of Medical Cell Biology, University of Uppsala, Box 571, 75 123 Uppsala, Sweden. anne-jacqueline.relova@medcellbiol.uu.se
Kampf
C
C
Roomans
G M
GM
D001249:Asthma / Q000276:immunology; D001980:Bronchi / Q000166:cytology; D002455:Cell Division / Q000187:drug effects / Q000276:immunology; D002470:Cell Survival / Q000187:drug effects / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D006801:Humans; D018793:Interleukin-13 / Q000494:pharmacology; D015847:Interleukin-4 / Q000494:pharmacology; D015848:Interleukin-5 / Q000494:pharmacology; D007378:Interleukins / Q000494:pharmacology*; D020545:Respiratory Mucosa / Q000166:cytology* / Q000187:drug effects / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology*
D018793:Interleukin-13; D015848:Interleukin-5; D007378:Interleukins; D015847:Interleukin-4