title: Comparison of erythromycin and oxytetracycline for the treatment of ovine footrot.
abstract: A microbiological study of 25 cases of ovine footrot was performed. Cultures belonging to Dichelobacter nodosus were isolated in 48% of the sampled animals. The sensitivity of the 99 strict anaerobic bacterial isolates to 5 antibiotics (penicillin G, amoxycillin, spiramycin, erythromycin and oxytetracycline) was studied. The percentage of resistant cultures was in all cases higher than 30%. The efficacy of erythromycin and oxytetracycline in the treatment of ovine footrot was studied. To conduct this test, an intramuscular injection was applied, of one antimicrobial or the other, at the beginning of the treatment. The tolerance of animals to the antimicrobials, the success rate of treatment and the severity of lameness were evaluated. The percentage of animals cured within 15 days was around 75%. In contrast, only 44% improvement was achieved in the lameness. No differences were found between the two antimicrobials in the above indices.
authors.affiliation: Unit of Microbiology, Department of Medicine and Animal Health, Veterinary Faculty, University of Extremadura, 10071 Cáceres, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Píriz
authors.forename: T
authors.initials: T
authors.lastname: Pobel
authors.forename: R
authors.initials: R
authors.lastname: Jiménez
authors.forename: E M
authors.initials: EM
authors.lastname: Mateos
authors.forename: P
authors.initials: P
authors.lastname: Martín-Palomino
authors.forename: P
authors.initials: P
authors.lastname: Vila
authors.forename: S
authors.initials: S
authors.lastname: Vadillo
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D020376:Dichelobacter nodosus / Q000187:drug effects; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005535:Foot Rot / Q000188:drug therapy* / Q000382:microbiology; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D007794:Lameness, Animal / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D010118:Oxytetracycline / Q000008:administration & dosage / Q000627:therapeutic use*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D004917:Erythromycin; D010118:Oxytetracycline