title: Local vs systemic corticosteroids in the treatment of carpal tunnel syndrome.
abstract: The authors compared the effectiveness of low-dose, short-term oral prednisolone vs local methylprednisolone injection in a prospective, double-blinded, parallel treatment study of carpal tunnel syndrome (CTS). A single injection of 15 mg methylprednisolone resulted in significant improvement in global symptom scores over a 12-week period. This study demonstrated the superiority of local steroid injection to oral steroid in the treatment of CTS.
authors.affiliation: Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, China. jsmwong@hkstar.com
authors.forename: S M
authors.initials: SM
authors.lastname: Wong
authors.forename: A C
authors.initials: AC
authors.lastname: Hui
authors.forename: A
authors.initials: A
authors.lastname: Tang
authors.forename: P C
authors.initials: PC
authors.lastname: Ho
authors.forename: L K
authors.initials: LK
authors.lastname: Hung
authors.forename: K S
authors.initials: KS
authors.lastname: Wong
authors.forename: R
authors.initials: R
authors.lastname: Kay
authors.forename: E
authors.initials: E
authors.lastname: Li
mesh_terms: D000284:Administration, Oral; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D002349:Carpal Tunnel Syndrome / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage*; D011446:Prospective Studies
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D008775:Methylprednisolone