Amyloid beta-peptide induces nitric oxide production in rat hippocampus: association with cholinergic dysfunction and amelioration by inducible nitric oxide synthase inhibitors.
Tran
M H
MH
Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya 466-8560, Japan.
Yamada
K
K
Olariu
A
A
Mizuno
M
M
Ren
X H
XH
Nabeshima
T
T
D000109:Acetylcholine / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000494:pharmacology*; D000818:Animals; D002552:Cerebral Ventricles; D010478:Chemotherapy, Cancer, Regional Perfusion; D018678:Cholinergic Agents; D006146:Guanidines / Q000494:pharmacology; D006624:Hippocampus / Q000187:drug effects* / Q000378:metabolism; D008569:Memory Disorders / Q000517:prevention & control; D017628:Microglia / Q000187:drug effects; D008954:Models, Biological; D009538:Nicotine / Q000494:pharmacology; D009569:Nitric Oxide / Q000096:biosynthesis*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors*; D052247:Nitric Oxide Synthase Type II; D010446:Peptide Fragments / Q000494:pharmacology*; D051381:Rats
D016229:Amyloid beta-Peptides; D018678:Cholinergic Agents; D006146:Guanidines; D010446:Peptide Fragments; C078592:amyloid beta-protein (1-40); D009569:Nitric Oxide; D009538:Nicotine; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; C496318:Nos2 protein, rat; D000109:Acetylcholine; C004479:pimagedine