title: Prenatal sonographic features of congenital lobar emphysema.
abstract: The prenatal sonographic features of congenital lobar emphysema (CLE) have not been well characterised. Five cases have been reported in the literature and on all these occasions either an echogenic (3) or a cystic (2) lung lesion was detected prenatally and the diagnosis was confirmed after the operation. This is the sixth case of CLE in the literature with prenatal sonographic features documented. The prenatal scans of a 23-year-old lady performed at 22 weeks of gestation revealed cystic lesions and increased echogenicity of the right fetal lung. There were no other anomalies and the karyotype was normal. The lesion decreased in size at 28 weeks and the baby was born by a normal vaginal delivery at 41 weeks. CT scan performed on day 6 confirmed cystic changes on the right lung with compression of the right lower lobe. A repeat CT scan performed at 4 months revealed extensive cystic changes in a hyper-inflated right lung and mediastinal shift to the left. At operation, abnormally inflated right upper and middle lobes were found suggesting a CLE. There were no subsequent complications after removal and histology confirmed CLE. The reported cases are reviewed and the prenatal sonographic features of CLE are discussed.
authors.affiliation: Department of Paediatric Surgery, Bristol Royal Children's Hospital, Bristol, UK.
authors.forename: R
authors.initials: R
authors.lastname: Babu
authors.forename: P
authors.initials: P
authors.lastname: Kyle
authors.forename: R D
authors.initials: RD
authors.lastname: Spicer
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011656:Pulmonary Emphysema / Q000151:congenital* / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal