title: Expanding drug resistance through integron acquisition by IncFI plasmids of Salmonella enterica Typhimurium.
abstract: We conducted a 30-year retrospective analysis of IncFI plasmids from Salmonella enterica serotype Typhimurium. These plasmids have been associated with the emergence of epidemic clones of multidrug-resistant Salmonella. Molecular and genetic evidence indicates that IncFI plasmids are evolving through sequential acquisition of integrons carrying different arrays of antibiotic- resistance genes.
authors.affiliation: Istituto Superiore di Sanità, Rome, Italy. alecara@iss.it
authors.forename: A
authors.initials: A
authors.lastname: Carattoli
authors.forename: L
authors.initials: L
authors.lastname: Villa
authors.forename: C
authors.initials: C
authors.lastname: Pezzella
authors.forename: E
authors.initials: E
authors.lastname: Bordi
authors.forename: P
authors.initials: P
authors.lastname: Visca
mesh_terms: D004352:Drug Resistance, Microbial; D010957:Plasmids; D012189:Retrospective Studies; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics*