In situ oxidation-imine formation-reduction routes from alcohols to amines.
Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.
Blackburn
L
L
Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK.
Taylor
R J
RJ