title: The protein kinase activity modulation sites: mechanisms for cellular regulation - targets for therapeutic intervention.
authors.affiliation: Roche Diagnostics GmbH, Pharma Research Penzberg, Germany.
authors.forename: R A
authors.initials: RA
authors.lastname: Engh
authors.forename: D
authors.initials: D
authors.lastname: Bossemeyer
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D020134:Catalytic Domain; D017868:Cyclic AMP-Dependent Protein Kinases / Q000037:antagonists & inhibitors / Q000737:chemistry; D004791:Enzyme Inhibitors / Q000737:chemistry; D006160:Guanosine Triphosphate / Q000378:metabolism; D008024:Ligands; D020935:MAP Kinase Signaling System; D008954:Models, Biological; D008957:Models, Genetic; D008958:Models, Molecular; D011485:Protein Binding; D011487:Protein Conformation; D020033:Protein Isoforms; D011494:Protein Kinases / Q000378:metabolism*; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D019311:Staurosporine / Q000737:chemistry
chemical_list: D004791:Enzyme Inhibitors; D008024:Ligands; D020033:Protein Isoforms; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate; D011494:Protein Kinases; D017868:Cyclic AMP-Dependent Protein Kinases; D019311:Staurosporine