title: Clinical investigation of a true color scanning laser ophthalmoscope.
abstract: OBJECTIVE
  To show true color scanning laser ophthalmoscope (SLO) images produced by simultaneously imaging the retina with red, green, and blue lasers.
  
  
  METHODS
  Low-power red, green, and blue lasers were combined using fiber optics. By rapidly pulsing the lasers, each point on the fundus is illuminated by the 3 colors in quick succession, with the total power level being similar to that from a single laser. The reflected light is then decoded to extract the red, green, and blue color information and the true color fundus image is displayed live on a computer monitor.
  
  
  RESULTS
  Comparison was made between the color SLO images from 5 patients and their digitized fundus photographs. The background fundus and retinal vasculature showed a similar appearance. The SLO gave better quality information in patients with ocular histoplasmosis, macular dystrophy, and optic disc drusen. By operating the color SLO in the indirect mode, macular edema could be clearly seen as lines and ridges surrounding the fovea.
  
  
  CONCLUSIONS
  The color SLO offers all the advantages of the present commercially available monochromatic device, with the added advantage of true color representation of the fundus without increasing either imaging time or the level of exposure.
authors.affiliation: Department of Biomedical Physics and Bioengineering, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, UK. mani@biomed.abdn.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Manivannan
authors.forename: J
authors.initials: J
authors.lastname: Van der Hoek
authors.forename: P
authors.initials: P
authors.lastname: Vieira
authors.forename: A
authors.initials: A
authors.lastname: Farrow
authors.forename: J
authors.initials: J
authors.lastname: Olson
authors.forename: P F
authors.initials: PF
authors.lastname: Sharp
authors.forename: J V
authors.initials: JV
authors.lastname: Forrester
mesh_terms: D000328:Adult; D003116:Color; D015821:Eye Infections, Fungal / Q000175:diagnosis; D005260:Female; D005654:Fundus Oculi; D006660:Histoplasmosis / Q000175:diagnosis; D006801:Humans; D007834:Lasers; D008268:Macular Degeneration / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D019721:Ophthalmoscopes; D009887:Ophthalmoscopy / Q000379:methods*; D015594:Optic Disk Drusen / Q000175:diagnosis; D010781:Photography / Q000379:methods; D012164:Retinal Diseases / Q000175:diagnosis*; D012171:Retinal Vessels / Q000473:pathology*; D012815:Signal Processing, Computer-Assisted