title: New alleles in the B44 family including B*44022, B*44032, B*4411, B*4420, B*4421, B*4424, and B*8301.
abstract: Seven new HLA-B locus alleles have been described. B*44022 and B*44032 are silent substitutions altering known alleles. B*4411 carries a unique Bw4-like epitope. B*4420, B*4421, and B*4424 carry new combinations of motifs previously observed in other alleles. B*8301 appears to be the result of the replacement of exon 2 from B*4402 with exon 2 from B*5603.
authors.affiliation: Department of Oncology, Georgetown University Medical Center, Washington, DC, USA.
authors.forename: N K
authors.initials: NK
authors.lastname: Steiner
authors.forename: C P
authors.initials: CP
authors.lastname: Gans
authors.forename: C
authors.initials: C
authors.lastname: Kosman
authors.forename: D
authors.initials: D
authors.lastname: Bradshaw
authors.forename: R
authors.initials: R
authors.lastname: Koester
authors.forename: E M
authors.initials: EM
authors.lastname: Menchaca
authors.forename: W
authors.initials: W
authors.lastname: Mitton
authors.forename: J
authors.initials: J
authors.lastname: Ng
authors.forename: R J
authors.initials: RJ
authors.lastname: Hartzman
authors.forename: C K
authors.initials: CK
authors.lastname: Hurley
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics / Q000276:immunology; D044466:Asian People / Q000235:genetics; D001483:Base Sequence; D015235:HLA-B Antigens / Q000235:genetics*; D059948:HLA-B44 Antigen; D006801:Humans; D008969:Molecular Sequence Data; D011995:Recombination, Genetic / Q000276:immunology; D044465:White People / Q000235:genetics
chemical_list: D015235:HLA-B Antigens; D059948:HLA-B44 Antigen