title: Ultrasound-guided percutaneous cholecystostomy in high-risk surgical patients.
abstract: OBJECTIVE
  In critically ill patients, cholecystectomy is associated with a high mortality rate. The aim of this study was to evaluate the safety, efficacy and long-term outcome of ultrasound-guided percutaneous cholecystostomy (USGPC) in critically ill patients with acute cholecystitis.
  
  
  METHODS
  Clinical records of 51 patients, all considered high-risk surgical patients, with acute cholecystitis treated with USGPC between 1987 and 1999, were retrospectively reviewed. Response was defined as improvement in clinical symptoms and signs, and/or reduction in c-reactive protein and white blood count levels within 72 h. Long-term results were evaluated by means of clinical records and written correspondence.
  
  
  RESULTS
  Gallbladder stones were seen in 28 patients whereas 23 had acalculous cholecystitis. Ninety percent showed clinical improvement after USGPC. Cholecystectomy was performed in 16%, of which 6% after recurrent cholecystitis. Recurrence of cholecystitis occurred in 22%. Hospital mortality was 16%. None of the deaths was procedure related or related to acute cholecystitis alone. Major complications relating to the USGPC were rare (4%), while minor catheter-related complications were quite common.
  
  
  CONCLUSIONS
  USGPC is a procedure with few complications and a high success rate. In patients with acalculous cholecystitis as well as in many patients with calculous cholecystitis, no further treatment was needed.
authors.affiliation: Department of Surgery, University Hospital, Uppsala, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Granlund
authors.forename: B M
authors.initials: BM
authors.lastname: Karlson
authors.forename: A
authors.initials: A
authors.lastname: Elvin
authors.forename: I
authors.initials: I
authors.lastname: Rasmussen
mesh_terms: D000368:Aged; D002764:Cholecystitis / Q000000981:diagnostic imaging* / Q000601:surgery*; D002767:Cholecystostomy / Q000379:methods*; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D018570:Risk Assessment; D012449:Safety; D016896:Treatment Outcome; D014463:Ultrasonography