Catalytic enantioselective synthesis of prostaglandin E(1) methyl ester using a tandem 1,4-addition-aldol reaction to a cyclopenten-3,5-dione monoacetal.
Arnold
L A
LA
Department of Organic and Molecular Inorganic Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Naasz
R
R
Minnaard
A J
AJ
Feringa
B L
BL
D000527:Alprostadil / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D002384:Catalysis; D013237:Stereoisomerism
C439321:prostaglandin E1 methyl ester; D000527:Alprostadil