The hunting of the Src.
The non-receptor tyrosine kinase Src is important for many aspects of cell physiology. The viral src gene was the first retroviral oncogene to be identified, and its cellular counterpart was the first proto-oncogene to be discovered in the vertebrate genome. Src has been important, not only as an object of study in itself, but also as an entry point into the molecular genetics of cancer.
Martin
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Department of Molecular and Cell Biology, University of California, 401 Barker Hall #3204, Berkeley, California 94720-3204, USA. smartin@socrates.berkeley.edu.
D000818:Animals; D015971:Gene Expression Regulation, Enzymologic; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009369:Neoplasms / Q000201:enzymology / Q000235:genetics; D000090063:Proto-Oncogene Mas; D015398:Signal Transduction; D019061:src-Family Kinases
C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D019061:src-Family Kinases