Analysis of histochemically and morphometrically in the anterior belly digastric muscle of osteopetrotic (op/op) mice.
The fibers of the anterior belly digastric muscle of mice, fed a granulated diet for various periods, have been studied histochemically and morphometrically. The diameters of the anterior belly digastric fibers in normal mice fed only a granulated diet were smaller than those in mice fed a solid diet. Differences in the succinate dehydrogenase (SDH) activity of muscle fibers between op/op and normal mice gradually appeared in the anterior belly digastric muscle and, by the age of 90 days, under-development of muscle fibers was observed in the mild-belly region of the anterior belly digastric muscle of op/op mice fed a granulated diet. These results indicate mechanical stress in mastication plays an important role in the development of the anterior belly digastric muscle structures.
Kawata
T
T
Department of Orthodontics, Hiroshima University School of Dentistry, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Fujita
T
T
Tokimasa
C
C
Sugiyama
H
H
Ozawa
S
S
Tanne
K
K
D000818:Animals; D004032:Diet; D006651:Histocytochemistry; D008409:Mastication; D008410:Masticatory Muscles / Q000201:enzymology / Q000473:pathology*; D051379:Mice; D008817:Mice, Mutant Strains; D018656:Muscle Fibers, Fast-Twitch / Q000201:enzymology / Q000473:pathology; D018485:Muscle Fibers, Skeletal / Q000201:enzymology / Q000473:pathology*; D010022:Osteopetrosis / Q000473:pathology*; D013314:Stress, Mechanical; D013385:Succinate Dehydrogenase / Q000378:metabolism
D013385:Succinate Dehydrogenase