Deep brain stimulation of the internal pallidum did not improve chorea in a patient with neuro-acanthocytosis.
We report the failure of bilateral globus pallidus internus deep brain stimulation to improve chorea in a patient with chorea-acanthocytosis. Prior to this surgery the patient had experienced a striking but short lived amelioration of symptoms with clozapine therapy.
Wihl
G
G
Department of Neurology, Heinrich-Heine-University Düsseldorf, Moorenstr 5, 40225 Düsseldorf, Germany. wihl@uni-duesseldorf.de
Volkmann
J
J
Allert
N
N
Lehrke
R
R
Sturm
V
V
Freund
H J
HJ
D000328:Adult; D002819:Chorea / Q000175:diagnosis / Q000628:therapy*; D018450:Disease Progression; D004599:Electric Stimulation Therapy / Q000379:methods*; D004567:Electrodes, Implanted; D005917:Globus Pallidus / Q000601:surgery; D006801:Humans; D008297:Male; D017211:Treatment Failure