[Bullous cutaneous mastocytosis revealed by acute disease secondary to morphine administration].
Mastocytosis in children shows in three clinical forms. The rarest is the diffuse or bullous form.


METHODS
Since one month of age an infant showed a diffuse erythema and vesicle rash. At four months of age, serious discomfort after morphinic absorption led to the diagnosis of bullous cutaneous mastocytosis. Histologic examination confirmed this diagnosis. The clinical severity led to intravenous corticosteroid and antihistamine therapy.


CONCLUSIONS
Bullous cutaneous mastocytosis is unusual in children. However, it should be considered if there are any doubts because of its serious complications and iatrogenic therapeutic risks. Some serious cases require intravenous corticosteroid therapy. Appropriate care enables a normal development with a disappearance of the disease before the teenage years.
Leblanc
L
L
Service de dermatologie, centre hospitalier universitaire de Dijon, 10, boulevard du Maréchal-de-Lattre-de-Tassigny, 21034 Dijon, France.
de Monléon
J V
JV
Faber
V
V
Beer
F
F
Dalac
S
S
Justrabo
E
E
Lambert
D
D
Huet
F
F
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007049:Iatrogenic Disease; D007223:Infant; D008297:Male; D009020:Morphine / Q000009:adverse effects*; D012720:Severity of Illness Index; D014582:Urticaria Pigmentosa / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology
D000305:Adrenal Cortex Hormones; D000701:Analgesics, Opioid; D006634:Histamine H1 Antagonists; D009020:Morphine