title: A catalytic-enantioselective entry to planar chiral pi-complexes: enantioselective methoxycarbonylation of 1,2-dichlorobenzene-Cr(CO)(3).
abstract: The palladium-catalyzed mono-methoxycarbonylation of 1,2-dichlorobenzene tricarbonylchromium(0) has been achieved with up to 95% ee in the presence of the chiral ferrocene ligand (R,S)-PPF-pyrrolidine. It was found that the enantioselectivity strongly depends on the reaction time (conversion). Obviously, the initial enantioselectivity is enhanced by a subsequent kinetic resolution connected to the formation of the bis-methoxycarbonylated byproduct.
authors.affiliation: Institut für Organische Chemie, Universität zu Köln, Greinstrasse 4 D-50939 Köln, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Gotov
authors.forename: H G
authors.initials: HG
authors.lastname: Schmalz