title: Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf.
authors.affiliation: Department of Microbiology and Immunology, Brody School of Medicine at East Carolina University, Greenville, NC 27858, USA. mccubreyj@mail.ecu.edu
authors.forename: J A
authors.initials: JA
authors.lastname: McCubrey
authors.forename: L S
authors.initials: LS
authors.lastname: Steelman
authors.forename: W L
authors.initials: WL
authors.lastname: Blalock
authors.forename: J T
authors.initials: JT
authors.lastname: Lee
authors.forename: P W
authors.initials: PW
authors.lastname: Moye
authors.forename: F
authors.initials: F
authors.lastname: Chang
authors.forename: M
authors.initials: M
authors.lastname: Pearce
authors.forename: J G
authors.initials: JG
authors.lastname: Shelton
authors.forename: M K
authors.initials: MK
authors.lastname: White
authors.forename: R A
authors.initials: RA
authors.lastname: Franklin
authors.forename: S C
authors.initials: SC
authors.lastname: Pohnert
mesh_terms: D000818:Animals; D015153:Blotting, Western; D002460:Cell Line; D016207:Cytokines / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D049452:Green Fluorescent Proteins; D006133:Growth Substances / Q000378:metabolism; D006801:Humans; D007377:Interleukin-3 / Q000378:metabolism; D007938:Leukemia / Q000378:metabolism; D008164:Luminescent Proteins / Q000378:metabolism; D020930:MAP Kinase Kinase Kinases / Q000378:metabolism; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism; D008954:Models, Biological; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D019908:Proto-Oncogene Proteins c-raf / Q000378:metabolism*; D012313:RNA / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D012190:Retroviridae / Q000235:genetics; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
chemical_list: D016207:Cytokines; D049452:Green Fluorescent Proteins; D006133:Growth Substances; D007377:Interleukin-3; D008164:Luminescent Proteins; D020930:MAP Kinase Kinase Kinases; D019950:Mitogen-Activated Protein Kinase 1; D019869:Phosphatidylinositol 3-Kinases; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins; D051057:Proto-Oncogene Proteins c-akt; D019253:Proto-Oncogene Proteins c-bcl-2; D019908:Proto-Oncogene Proteins c-raf; D012313:RNA; D011993:Recombinant Fusion Proteins; D013936:Thymidine; C494918:AKT1 protein, human