title: Treatment of tuberculum sellae meningiomas:a long-term follow-up study.
abstract: Surgical techniques and their results for tuberculum sellae meningiomas were studied. Thirty-three cases, the first of which was operated in 1980, were analysed. There were 4 men and 29 women with an average age of 46.7 years. Eight cases underwent reoperations. The mean follow-up was 10.7 years. Approaches were pterional for 15 patients, FOZ/FO for 10, bilateral subfrontal for 6, and others for 2. Simpson's grade (I, II, III, IV) were 12, 9, 0, and 12 cases respectively. Recurrence rate was 0% for grade I and 58.3% for grade IV. The FOZ/FO approach resulted in a lower Simpson's grade (P=0.05), but other factors were not related to Simpson's grade (P=0.05). The postoperative visual outcome did not depend on total (grade I and II) or subtotal (grade III and IV) removal (P=0.01). We conclude that radical removal of the tumours may result in lower recurrence rate without increasing surgical complications. Furthermore, skull base approaches can improve the rate of radical removal of tuberculum sellae meningiomas.
authors.affiliation: Department of Neurosurgery, Kobe University School of Medicine, Kobe City, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ohta
authors.forename: K
authors.initials: K
authors.lastname: Yasuo
authors.forename: M
authors.initials: M
authors.lastname: Morikawa
authors.forename: T
authors.initials: T
authors.lastname: Nagashima
authors.forename: N
authors.initials: N
authors.lastname: Tamaki
mesh_terms: D000328:Adult; D003399:Craniotomy / Q000379:methods; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008579:Meningioma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D020221:Optic Nerve Injuries / Q000517:prevention & control; D012086:Reoperation; D012658:Sella Turcica / Q000601:surgery; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology