Molecular Features of Energy Coupling in the F(0)F(1) ATP Synthase.
H(+) translocation is coupled to ATP synthesis in the F(0)F(1) ATP synthase via a rotary mechanism. Catalytic turnover, site-site cooperativity, and H(+) transport obligatorily involve rotation of a set of subunits. The transport domain in the membranous F(0) and the catalytic domain in the F(1) are mechanisms designed for generating torque.
Nakamoto
Robert K.
RK
Department of Molecular Physiology and Biological Physics at the University of Virginia, PO Box 10011, Charlottesville, VA 22906-0011, USA.