title: Aromatase regulation and breast cancer.
authors.affiliation: Endocrinology and Metabolic Medicine, Imperial College School of Medicine, St Mary's Hospital, London, UK. m.reed@ic.ac.uk
authors.forename: M J
authors.initials: MJ
authors.lastname: Reed
authors.forename: A
authors.initials: A
authors.lastname: Purohit
mesh_terms: D000077584:2-Methoxyestradiol; D000328:Adult; D000818:Animals; D001141:Aromatase / Q000032:analysis / Q000378:metabolism*; D047072:Aromatase Inhibitors; D001189:Aryl Hydrocarbon Hydroxylases; D001940:Breast / Q000378:metabolism; D001943:Breast Neoplasms / Q000188:drug therapy / Q000201:enzymology*; D019389:Cytochrome P-450 CYP2D6 / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D004041:Dietary Fats / Q000009:adverse effects; D015232:Dinoprostone / Q000378:metabolism; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D004958:Estradiol / Q000031:analogs & derivatives / Q000378:metabolism; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D000077289:Letrozole; D008875:Middle Aged; D009570:Nitriles / Q000627:therapeutic use; D009765:Obesity / Q000201:enzymology; D010575:Pesticides / Q000009:adverse effects; D039181:Steroid 16-alpha-Hydroxylase; D013250:Steroid Hydroxylases / Q000378:metabolism; D014230:Triazoles / Q000627:therapeutic use
chemical_list: D047072:Aromatase Inhibitors; D016207:Cytokines; D004041:Dietary Fats; D004791:Enzyme Inhibitors; D004967:Estrogens; D009570:Nitriles; D010575:Pesticides; D014230:Triazoles; D004958:Estradiol; D000077584:2-Methoxyestradiol; D000077289:Letrozole; D003577:Cytochrome P-450 Enzyme System; D013250:Steroid Hydroxylases; D001141:Aromatase; D001189:Aryl Hydrocarbon Hydroxylases; D019389:Cytochrome P-450 CYP2D6; D039181:Steroid 16-alpha-Hydroxylase; D015232:Dinoprostone