Alkynoates as a source of reactive alkylinides for aldehyde addition reactions.
[see reaction]. The reaction of activated alkynes with carbonyl compounds in the presence of a catalytic amount of a nucleophile leads to enol-protected functionalized propargyl alcohols and 1,3-dioxolane compounds by way of a mild carbon-carbon bond formation reaction.
de Armas
P
P
Instituto de Productos Naturales y Agrobiología, CSIC, Avda. Astrofísico Fco. Sánchez 3, 38206 La Laguna, Santa Cruz de Tenerife, Spain. parmas@ipna.csis.es
García-Tellado
F
F
Marrero-Tellado
J J
JJ
Tejedor
D
D
Maestro
M A
MA
Gonzalez-Platas
J
J