Medical therapy of neurocardiogenic syncope.
Neurocardiogenic syncope, alternatively called vasovagal, vasodepressor, or neurally mediated syncope, is a clinical syndrome faced by many clinicians. Its pathophysiology is complicated and not fully understood. Multiple pharmacologic therapies have been evaluated, with no clear ideal agent. Decisions regarding tilt-table testing, selection of pharmacotherapy, and assessment of drug efficacy are not straightforward. This article attempts to assess these issues.
Cadman
C S
CS
Division of Cardiology, Department of Medicine, University of New Mexico, Albuquerque, New Mexico, USA. ckcadman@nm.net
D000293:Adolescent; D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D002648:Child; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D004206:Disopyramide / Q000627:therapeutic use; D005440:Fluid Therapy; D006801:Humans; D008901:Mineralocorticoids / Q000627:therapeutic use; D010275:Parasympathetic Nervous System / Q000503:physiopathology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D017673:Sodium Chloride, Dietary / Q000627:therapeutic use; D013564:Sympathetic Nervous System / Q000503:physiopathology; D019462:Syncope, Vasovagal / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D013806:Theophylline / Q000627:therapeutic use; D018667:Tilt-Table Test
D000316:Adrenergic alpha-Agonists; D000319:Adrenergic beta-Antagonists; D018680:Cholinergic Antagonists; D004206:Disopyramide; D008901:Mineralocorticoids; D017367:Selective Serotonin Reuptake Inhibitors; D017673:Sodium Chloride, Dietary; D013806:Theophylline