title: Accuracy and precision of flowing afterglow mass spectrometry for the determination of the deuterium abundance in the headspace of aqueous liquids and exhaled breath water.
abstract: We have assessed the accuracy and precision of our flowing afterglow mass spectrometric method (FA-MS) for absolute measurements of deuterium abundance in water using standardised tap water/D(2)O mixtures within the D/H range from 155 ppm (local tap water) to 1104 ppm, prepared by the gravimetric method. The results of this study show that a precision and accuracy of 1% can be achieved for the deuterium abundance in water samples. This is quite adequate for the main application, which is the rapid, non-invasive measurement of total body water by deuterium analysis of breath water vapour using the D(2)O dilution method.
authors.affiliation: V. Cermák Laboratory, J. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Dolejskova 3, 182 23, Prague 8, Czech Republic.
authors.forename: P
authors.initials: P
authors.lastname: Spanel
authors.forename: D
authors.initials: D
authors.lastname: Smith
mesh_terms: D001834:Body Water / Q000737:chemistry*; D003903:Deuterium / Q000032:analysis*; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D012119:Respiration; D012680:Sensitivity and Specificity
chemical_list: D003903:Deuterium