title: [Neuro-navigation in the central area: impact on different surgical steps related to the location and various pathological processes].
abstract: The neurosurgical treatment of space occupying processes in the central area bears a relatively high risk of either postoperative neurological deficits ("radical approach") or of residual tumor ("conservative approach"). Therefore, special techniques of intraoperative topographic orientation (image-guided surgery) play an important role here. The possible impact of neuronavigation on different neurosurgical steps (craniotomy, corticotomy, localization of the process, definition of borders of resection) was studied in relation to the site of pathology (extraaxial, intraaxial/superficial, intraaxial/deep) in 46 patients harbouring space occupying lesions of the central area. In intraaxial pathologies, additional electrophysiological monitoring was done. It could be shown, that in cases of deep seated processes, neuronavigation had the greatest impact on craniotomy, corticotomy and localization of the process, whereas the borders of resection were defined predominantly on the basis of differences in colour or consistency. In extraaxial pathologies, neuronavigation was of significance only for craniotomy; in intraaxial processes visible at the surface, it had an impact on craniotomy and--in a few cases--on definition of resection borders. In neurosurgery of intraaxial pathologies of the central area (particularly those not visible at the surface), the use of neuronavigation (or another method of intraoperative localization) in combination with neurophysiologic monitoring is strongly recommended.
authors.affiliation: Neurochirurgische Universitätsklinik, Johannes Gutenberg-Universität, Mainz. wagner@nc.klinik.uni-mainz.de
authors.forename: W
authors.initials: W
authors.lastname: Wagner
authors.forename: M R
authors.initials: MR
authors.lastname: Gaab
authors.forename: H W
authors.initials: HW
authors.lastname: Schroeder
authors.forename: J
authors.initials: J
authors.lastname: Piek
authors.forename: W R
authors.initials: WR
authors.lastname: Niendorf
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging / Q000601:surgery*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D002540:Cerebral Cortex / Q000601:surgery; D002648:Child; D003399:Craniotomy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D019635:Neurosurgical Procedures / Q000379:methods*; D011184:Postoperative Period; D014057:Tomography, X-Ray Computed