A new technique to elevate night time growth hormone release and a potential growth hormone feedback control loop.
A new technique for controllable elevation of night time growth hormone (GH) release in adult humans involves a synergy between oral intake of the naturally occurring compounds acetyl-L-carnitine (500 mg) and L-ornithine (25-100 mg) taken at night time sleep after a 3 to 4 hour fast. The set point for normal hypothalamic GH release appears to include a 'whole body' mitochondrial State 3 status 'feed back loop' controlled by systemic acetyl- L-carnitine levels.
Parr
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Department of Medicine, University of Southern California, Los Angeles, USA. tyParr@compuserve.com
D000108:Acetylcarnitine / Q000008:administration & dosage* / Q000494:pharmacology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002940:Circadian Rhythm; D005246:Feedback; D005260:Female; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009952:Ornithine / Q000008:administration & dosage* / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects
D000108:Acetylcarnitine; D013006:Growth Hormone; D009952:Ornithine