title: Overview of isoprene monomer and polyisoprene production processes.
abstract: Isoprene monomer is employed in the manufacture of polyisoprene and various copolymers (with isobutylene, butadiene, styrene, other monomers). Recent surveys of air levels of isoprene in US monomer and polymer manufacturing facilities have demonstrated TWA concentrations <1 ppm in 90% of collected samples, and 98% were <10 ppm. Tumorigenic responses have been observed in isoprene-exposed rodents. However, the relevance of these findings to health in occupational environments can only be assessed following completion of additional and ongoing mechanistic research.
authors.affiliation: The Goodyear Tire and Rubber Company, 1485 E. Archwood Ave., Akron, OH 44306, USA. apleber@goodyear.com
authors.forename: A P
authors.initials: AP
authors.lastname: Leber
mesh_terms: D000395:Air Pollutants, Occupational / Q000032:analysis / Q000633:toxicity; D000818:Animals; D002070:Butadienes / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D002617:Chemical Industry; D045782:Hemiterpenes; D006801:Humans; D009374:Neoplasms, Experimental / Q000139:chemically induced; D016273:Occupational Exposure; D016272:Occupational Health; D010420:Pentanes; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D014481:United States
chemical_list: D000395:Air Pollutants, Occupational; D002070:Butadienes; D045782:Hemiterpenes; D010420:Pentanes; D011108:Polymers; C005059:isoprene