St John's wort for depression: what's the evidence?
There is a moderate amount of evidence to suggest that St John's wort is better than placebo in the short-term management of mild to moderate depressive illness, but there is increasing concern over reports of drug interactions. This article examines the scientific evidence and discusses relevant clinical issues.
Kelly
B D
BD
Stanley Research Centre Ireland, St John of God Hospital, Stillorgan, Dublin, Ireland.
D003863:Depression / Q000628:therapy*; D018765:Dopamine Uptake Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D004347:Drug Interactions; D006801:Humans; D020902:Hypericum / Q000009:adverse effects / Q000627:therapeutic use*; D008517:Phytotherapy; D010946:Plants, Medicinal; D016032:Randomized Controlled Trials as Topic; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
D018765:Dopamine Uptake Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors