Synthesis of styrenes through the biocatalytic decarboxylation of trans-cinnamic acids by plant cell cultures.
A novel method for producing styrenes from trans-cinnamic acids was developed. When trans-cinnamic acid was incubated with plant cell cultures at room temperature, styrene was obtained. 4-Hydroxy-3-methoxystyrene (2a), 3-nitrostyrene (2f) and furan (2g) were synthesized quantitatively.
Takemoto
M
M
School of Pharmaceutical Sciences, University of Shizuoka, Japan. takemoto@ys2.u-shizuoka-ken.ac.jp
Achiwa
K
K
D002262:Carboxy-Lyases / Q000378:metabolism; D002384:Catalysis; D002478:Cells, Cultured; D002934:Cinnamates / Q000737:chemistry*; D003373:Coumaric Acids / Q000737:chemistry; D003653:Decarboxylation; D006139:Guaiacol / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D006360:Heat-Shock Proteins / Q000737:chemistry; D018832:Molecular Chaperones / Q000737:chemistry; D009581:Nitrofurans / Q000138:chemical synthesis; D010944:Plants / Q000201:enzymology / Q000378:metabolism*; D013343:Styrenes / Q000138:chemical synthesis*
D002934:Cinnamates; D003373:Coumaric Acids; D006360:Heat-Shock Proteins; D018832:Molecular Chaperones; D009581:Nitrofurans; D013343:Styrenes; C011955:beta-nitrostyrene; D006139:Guaiacol; C014245:4-vinylguaiacol; C004999:ferulic acid; D002262:Carboxy-Lyases