title: MRI: a role in clinical trials.
abstract: The diagnosis and treatment of breast cancer has evolved significantly over the last 20 years. Breast-conserving therapy is replacing the Halstedian concept of "en bloc" resection. Difficulties in detection, pre- and postoperative planning and follow up continue to challenge the clinician. Women at high risk present a significant clinical dilemma. MRI technology in many of these areas is providing more information about detection, tumor size, extent, and response to treatment. The careful and thoughtful inclusion of MRI in clinical trials may help continue the advancement of breast cancer care. J. Magn. Reson. Imaging 2001;13:837-841.
authors.affiliation: Division of Surgical Oncology, Western Pennsylvania Allegheny Health System, Pittsburgh, PA 15212, USA.
authors.forename: T B
authors.initials: TB
authors.lastname: Julian
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000628:therapy; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D020360:Neoadjuvant Therapy; D016896:Treatment Outcome