The Time Course of Signaling at Central Glutamatergic Synapses.
Glutamate is the main excitatory transmitter in the mammalian CNS, mediating fast synaptic transmission primarily by activation of AMPA-type glutamate receptor channels. Both synaptic structure and a cell-specific molecular switch in the AMPA receptor subunit expression are involved in the regulation of the synaptic signaling time course.
Jonas
Peter
P
Physiologisches Institut der Universität Freiburg, D-79104 Freiburg, Germany.