title: Splenectomy combined with cesarean section in a patient with severe immunological thrombocytopenic purpura refractory to medical therapy.
abstract: Splenectomy as a treatment for severe immunological thrombocytopenic purpura is rarely performed in the third trimester of pregnancy. We report a 28-year-old patient who presented at the 34th gestational week with severe immunological thrombocytopenic purpura resistant to both corticosteroid and intravenous immunoglobulin therapies. Splenectomy combined with delivery by cesarean section provided remission of the disease.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Ege University, Bornova, Izmir, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Sendag
authors.forename: M
authors.initials: M
authors.lastname: Kazandi
authors.forename: M C
authors.initials: MC
authors.lastname: Terek
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002585:Cesarean Section; D004351:Drug Resistance; D005260:Female; D005865:Gestational Age; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D017713:Platelet Transfusion; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000601:surgery*; D011256:Pregnancy Outcome; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000601:surgery*; D012074:Remission Induction; D013156:Splenectomy
chemical_list: D000305:Adrenal Cortex Hormones; D016756:Immunoglobulins, Intravenous