title: Metastatic calcification of the nasal septum presenting as an intraoral mass: a case report with a review of the literature.
abstract: Metastatic calcification is a pathologic condition characterized by deposition of calcified product in otherwise normal tissues as a result of hyperphosphatemia with or without concurrent hypercalcemia. Metastatic calcification presenting clinically as an oral lesion is extremely rare. To date, only 7 cases of metastatic calcification involving the oral soft tissues have been described. This report describes a case of metastatic calcification of the nasal septum presenting as a mass of the anterior maxillary vestibule in a patient with end-stage renal disease. The case reported is only the second example with nasal septum involvement. A brief review of the clinical and histopathologic features of previously reported intraoral cases is also presented.
authors.affiliation: Oral and Maxillofacial Pathology, Flushing, NY, USA.
authors.forename: F
authors.initials: F
authors.lastname: Alawi
authors.forename: P D
authors.initials: PD
authors.lastname: Freedman
mesh_terms: D002114:Calcinosis / Q000175:diagnosis* / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D008439:Maxillary Diseases / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D009300:Nasal Septum / Q000473:pathology*; D009668:Nose Diseases / Q000175:diagnosis* / Q000473:pathology