Long-term outcome of patients surviving for more than ten years following treatment for acute leukaemia.
Between 1972 and 1988, 832 consecutive patients were treated for acute leukaemia at St. Bartholomew's Hospital; a retrospective analysis has been conducted to determine the clinical course and outcome for 101 who have survived > or = 10 years following treatment. At a median follow-up of 16 years (range 10-28 years), 86 patients (86 out of 834 total, 11%) were still alive. Long-term follow-up of patients who have survived > or = 10 years following treatment for acute leukaemia revealed that most patients were in normal health, although a significant number of complications had occurred.
Micallef
I N
IN
Department of Medical Oncology, St. Bartholomew's Hospital, London, UK.
Rohatiner
A Z
AZ
Carter
M
M
Boyle
M
M
Slater
S
S
Amess
J A
JA
Lister
T A
TA
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D016026:Bone Marrow Transplantation; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007938:Leukemia / Q000401:mortality* / Q000601:surgery; D007951:Leukemia, Myeloid / Q000401:mortality / Q000601:surgery; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000401:mortality / Q000601:surgery; D011788:Quality of Life; D012074:Remission Induction; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome