Biocatalysis in ionic liquids: markedly enhanced enantioselectivity of lipase.
[reaction: see text] Lipase-catalyzed transesterifications in ionic liquids proceeded with markedly enhanced enantioselectivity. It was observed that lipases were up to 25 times more enantioselective in ionic liquids than in conventional organic solvents.
Kim
K W
KW
National Research Laboratory of Chirotechnology, Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, San 31 Hyojadong, Pohang, Kyungbuk 790-784, Korea.
Song
B
B
Choi
M Y
MY
Kim
M J
MJ
D016956:Burkholderia cepacia / Q000201:enzymology; D002175:Candida / Q000201:enzymology; D002384:Catalysis; D007477:Ions / Q000494:pharmacology*; D008049:Lipase / Q000187:drug effects / Q000378:metabolism*; D012997:Solvents / Q000494:pharmacology; D013237:Stereoisomerism
D007477:Ions; D012997:Solvents; D008049:Lipase