B lymphocyte activation by contact-mediated interactions with T lymphocytes.
T cell dependent B lymphocyte activation requires interactions between numerous receptor-ligand pairs on the two cell types. Recently, advances have been made both in understanding how these various signals regulate B cell effector functions and in identifying many new receptor-ligand pairs that contribute to the regulation of B cell function by T lymphocytes.
Bishop
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GA
Departments of Microbiology and Internal Medicine, 3-501 Bowen Science Building, The University of Iowa, and VA Medical Center, 52242, Iowa City, IA, USA. gail-bishop@uiowa.edu
Hostager
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BS
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D002448:Cell Adhesion / Q000276:immunology; D002450:Cell Communication / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology*; D008211:Lymphocyte Cooperation; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism