title: Arsenite-induced multiple antibiotic resistance phenotype in environmental isolates of Yersinia enterocolitica.
abstract: Minimal inhibitory concentrations (MICs) of five antibiotics namely amikacin, gentamicin, tetracycline, ciprofloxacin, and nitrofurantoin for pork isolates of Yersinia enterocolitica increased two- to eightfold after bacteria were grown in the presence of 5 mm arsenite. For Y. enterocolitica isolates obtained from wastewater (sewage effluents), an unequivocal increase in MICs was seen with amikacin and gentamicin. No change was discernible in the outer-membrane proteins after isolates were grown in the presence of arsenite.
authors.affiliation: Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi-110021, India. micro@dusc.ernet.in
authors.forename: J S
authors.initials: JS
authors.lastname: Virdi
authors.forename: I
authors.initials: I
authors.lastname: Sinha
authors.forename: P
authors.initials: P
authors.lastname: Rajendran
authors.forename: I
authors.initials: I
authors.lastname: Singh
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018053:Arsenites / Q000494:pharmacology*; D001425:Bacterial Outer Membrane Proteins / Q000032:analysis; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D008460:Meat / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D012722:Sewage / Q000382:microbiology; D013552:Swine; D015008:Yersinia enterocolitica / Q000737:chemistry / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D018053:Arsenites; D001425:Bacterial Outer Membrane Proteins; D012722:Sewage; C015001:arsenite