Fine needle aspiration of breast myofibroblastoma. A case report.
BACKGROUND
The use of fine needle aspiration cytology (FNAC) for the diagnosis of breast diseases in men has received little attention. We report the cytologic and histologic findings of myofibroblastoma of the breast in a 52-year-old man.


METHODS
Smears disclosed irregular and cohesive sheets of cells, with ill-defined cytoplasm and oval nuclei containing single nucleoli. The nuclear membrane was frequently grooved, and occasional intranuclear cytoplasmic inclusions (pseudoinclusions) were also found. The background was clean and contained scarce collagenous stroma and fragments of myxoid material. To the best of our knowledge, there have been only seven previous reports of breast myofibroblastoma in which the cytologic features are well documented, and none of them mention the presence of pseudoinclusions.


CONCLUSIONS
FNAC could suggest the diagnosis of this distinctly uncommon tumor if evaluated together with the clinical and radiologic findings.
López-Ríos
F
F
Department of Pathology, 12 de Octubre University Hospital and Severo Ochoa Hospital, Madrid, Spain.
Burgos
F
F
Madero
S
S
Ballestín
C
C
Martínez-González
M A
MA
de Agustín
P
P
D001707:Biopsy, Needle; D018567:Breast Neoplasms, Male / Q000473:pathology* / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D006801:Humans; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000473:pathology* / Q000648:ultrastructure