The junction-resolving enzymes.
Junction-resolving enzymes are ubiquitous nucleases that are important for DNA repair and recombination and act on DNA molecules containing branch points, especially four-way junctions. They show a pronounced selectivity for the structure of the DNA substrate but, despite its importance, the structural selectivity is not well understood. This poses an intriguing challenge in molecular recognition on a relatively large scale.
Lilley
D M
DM
CRC Nucleic Acid Structure Research Group, Department of Biochemistry, University of Dundee, Dundee DD1 5EH, UK. dmjlilley@bad.dundee.ac.uk
White
M F
MF
D000818:Animals; D004260:DNA Repair; D004706:Endodeoxyribonucleases; D006801:Humans; D011995:Recombination, Genetic
D004706:Endodeoxyribonucleases