EARLY FLOWERING3 encodes a novel protein that regulates circadian clock function and flowering in Arabidopsis.
Higher plants use photoperiodic cues to regulate many aspects of development, including the transition from vegetative to floral development. The EARLY FLOWERING3 (ELF3) gene is required for photoperiodic flowering and normal circadian regulation in Arabidopsis. We have cloned ELF3 by positional methods and found that it encodes a novel 695-amino acid protein that may function as a transcriptional regulator. ELF3 transcript level is regulated in a circadian manner, as is expected of a zeitnehmer input pathway component. Overexpression of the LATE ELONGATED HYPOCOTYL gene, which has been proposed to function as a clock component, did not abolish circadian regulation of ELF3 transcription, providing further evidence that ELF3 is a circadian clock input pathway component.
Hicks
K A
KA
Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA.
Albertson
T M
TM
Wagner
D R
DR
D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000502:physiology; D029681:Arabidopsis Proteins; D001483:Base Sequence; D002940:Circadian Rhythm / Q000235:genetics*; D003001:Cloning, Molecular; D018744:DNA, Plant; D004268:DNA-Binding Proteins / Q000235:genetics; D017343:Genes, Plant; D008969:Molecular Sequence Data; D010940:Plant Proteins / Q000235:genetics* / Q000502:physiology; D018520:Plant Shoots / Q000254:growth & development; D012333:RNA, Messenger; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000235:genetics* / Q000502:physiology; D014158:Transcription, Genetic
D029681:Arabidopsis Proteins; D018744:DNA, Plant; D004268:DNA-Binding Proteins; D010940:Plant Proteins; D012333:RNA, Messenger; D014157:Transcription Factors; C432430:At2g25930 protein, Arabidopsis; C113192:LHY protein, Arabidopsis