Neurogenic inflammation in human and rodent skin.
The combination of vasodilation and protein extravasation following activation of nociceptors has been termed "neurogenic inflammation." In contrast to rodents, no neurogenic protein extravasation can be elicited in healthy human skin. Dermal microdialysis has considerably increased our knowledge about neurogenic inflammation in human skin, including the involvement of mast cells.
Schmelz
M
M
Department of Physiology, University of Erlangen, 91054 Erlangen, Germany.
Petersen
L J
LJ
D000818:Animals; D006801:Humans; D020078:Neurogenic Inflammation / Q000276:immunology* / Q000378:metabolism*; D012377:Rodentia; D012867:Skin / Q000276:immunology* / Q000294:innervation*