[Yeast count in urine. Review of the literature and preliminary results of a multicenter prospective study carried out in 15 hospital centers].
Candida spp. are increasingly involved in nosocomial infections in severely ill patients and the diagnosis is difficult. In this context, the significance of candiduria remains unclear. Management of this condition is still equivocal, because of the lack of information about its natural history and its predictive value for disseminated infection. Little is known about the discriminant value of colony count. After a comprehensive review of the available published data, the preliminary results of a multicentric prospective survey in critically ill patients hospitalised in intensive care units are given. The aim of the study was to search for correlations between quantitative candiduria and known risk factors for disseminated candidiasis. There is a statistically significant correlation (p = 0.003) between heavy candiduria (> 10(4) cfu.mL-1) and high Pittet colonisation index (> or = 0.5). Quantification of candiduria could be useful to select patients at high risk for disseminated candidiasis.
Chabasse
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Laboratoire de parasitologie-mycologie, centre hospitalier universitaire, 4, rue Larrey, 49033 Angers, France.
D000328:Adult; D000368:Aged; D002177:Candidiasis / Q000453:epidemiology / Q000382:microbiology* / Q000652:urine*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies