Fine-needle aspiration of hepatocellular carcinoma: False-negative result due to epithelioid cells.
The presence of epithelioid cells in fine-needle aspirations of a liver nodule is rare, but may complicate the diagnosis of the nodule. We report on a case of a liver nodule in hepatitis C cirrhosis. Results of fine-needle aspiration mainly revealed the presence of epithelioid cells, without any recognizable tumor cells. Histological examination of the nodule after surgical resection showed a hepatocellular carcinoma with numerous epithelioid and gigantocellular granulomas, without necrosis.
Mourra
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N
Service d'Anatomie Pathologique, Hôpital St.-Antoine, Paris, France. najat.mourra@free.fr
Flejou
J F
JF
D001707:Biopsy, Needle; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology*; D005188:False Negative Reactions; D006099:Granuloma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged