title: Evaluation of vaccine-induced maternal immunity against classical swine fever.
abstract: The vaccine-induced maternal immunity against classical swine fever (CSF) was investigated in this study. Eight sows were vaccinated with the Chinese strain of classical swine fever virus (CSFV). The length of time between vaccination and farrowing was 167-217 days. Milk samples from the front, middle and back udder sections and blood samples were taken from the sows on days 3 and 14 after farrowing. Blood samples were obtained from the piglets at the age of 3, 6 and 10 weeks. The antibody level of the milk was examined by ELISA, and that of blood samples by the virus neutralization (VN) test as well. In all 3-week-old piglets and in 80% of the 6-week-old animals the neutralizing antibody level reached the titre of 1:40. In none of the 10-week-old piglets did the titre exceed the value of 1:20, but in about 25% of the piglets it reached 1:20; the half of these piglets came from two litters. In none of the piglets did the antibody level reach the negative threshold in the ELISA test during the study. No significant differences were found between the udder sections in milk antibody level by ELISA.
authors.affiliation: Department of Microbiology and Infectious Diseases, Faculty of Veterinary Science, Szent István University, H-1581 Budapest, P.O. Box 22, Hungary. soos@novell.vmri.hu
authors.forename: P
authors.initials: P
authors.lastname: Soós
authors.forename: M
authors.initials: M
authors.lastname: Mojzis
authors.forename: A
authors.initials: A
authors.lastname: Pollner
authors.forename: L
authors.initials: L
authors.lastname: Sümeghy
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis / Q000097:blood; D006691:Classical Swine Fever / Q000276:immunology*; D006692:Classical Swine Fever Virus / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D007112:Immunity, Maternally-Acquired / Q000276:immunology*; D008892:Milk / Q000276:immunology / Q000821:virology; D009500:Neutralization Tests / Q000662:veterinary; D011247:Pregnancy; D013552:Swine; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines