title: Control of an outbreak of infection due to extended-spectrum beta-lactamase--producing Escherichia coli in a liver transplantation unit.
abstract: We report an outbreak of infection due to genotypically identical extended-spectrum beta-lactamase--producing Escherichia coli among patients in a liver transplantation unit. Control of the outbreak was achieved by a combination of contact isolation, feedback on hand hygiene, and gut decontamination with an orally administered fluoroquinolone. These interventions led to abrupt curtailment of the outbreak.
authors.affiliation: Infectious Disease Section, Veterans Affairs Medical Center, Pittsburgh, PA, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Paterson
authors.forename: N
authors.initials: N
authors.lastname: Singh
authors.forename: J D
authors.initials: JD
authors.lastname: Rihs
authors.forename: C
authors.initials: C
authors.lastname: Squier
authors.forename: B L
authors.initials: BL
authors.lastname: Rihs
authors.forename: R R
authors.initials: RR
authors.lastname: Muder
mesh_terms: D004196:Disease Outbreaks; D004926:Escherichia coli / Q000201:enzymology*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D006757:Hospital Units; D006801:Humans; D017053:Infection Control / Q000379:methods*; D016031:Liver Transplantation; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases