title: Metastatic transitional cell carcinoma of the urinary bladder presenting as a mandibular gingival swelling.
abstract: Oral cavity metastases mostly originate from the breasts, lungs, or kidneys. Transitional cell carcinoma (TCC), the most frequent malignant tumor of the urinary bladder, rarely metastasizes to the jaws. To the best of our knowledge, only 8 cases of bladder carcinoma have been reported in the English literature to metastasize to the jawbones. A new case of mandibular metastasis of urinary bladder TCC with extension to the gingiva is presented in a 64-year-old white man. The patient was referred for a periodontal infection of the upper right first molar. The clinical examination also showed a gingival swelling located in the lower left premolar region with a hypoasthesia of the left side of the lower lip. The gingival mass was biopsied, and the microscopy showed a mandibular metastatic TCC of the urinary bladder extending to the gingiva. Periodontists should be aware that, although gingival metastases are rare, when they occur they may mimic other local benign pathological conditions.
authors.affiliation: Division of Stomatology and Oral Surgery, School of Dental Medicine, Faculty of Medicine, University of Geneva, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: de Courten
authors.forename: C
authors.initials: C
authors.lastname: Irle
authors.forename: J
authors.initials: J
authors.lastname: Samson
authors.forename: T
authors.initials: T
authors.lastname: Lombardi
mesh_terms: D001641:Bicuspid; D001706:Biopsy; D001859:Bone Neoplasms / Q000556:secondary; D002295:Carcinoma, Transitional Cell / Q000473:pathology / Q000556:secondary*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005500:Follow-Up Studies; D005887:Gingival Neoplasms / Q000473:pathology / Q000556:secondary*; D006801:Humans; D006987:Hypesthesia / Q000175:diagnosis; D008046:Lip / Q000294:innervation; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology / Q000556:secondary*; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000473:pathology*