[The role of putrescine in of oxidative stress defense genes expression regulation in Escherichia coli].
The role of putrescine in the adaptive response of Escherichia coli grown aerobically in synthetic M9 medium with glucose to the H2O2-induced oxidative stress was studied. Under oxidative stress, the expression of the single-copy reporter gene fusions oxyR::lacZ and katG::lacZ was found to undergo biphasic changes, which were most pronounced in glucose-starved E. coli cells. The concentration-dependent activating effect of putrescine on the expression of the oxyR regulon genes was maximum when the oxyR gene was inhibited by high concentrations of hydrogen peroxide.
Tkachenko
A G
AG
Institute of Ecology and Genetics of Microorganisms, Ural Division, Russian Academy of Sciences, ul. Lenina 11, Perm, 614600 Russia.
Nesterova
L Iu
LIu
D000220:Adaptation, Biological / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D018384:Oxidative Stress / Q000235:genetics; D011700:Putrescine / Q000378:metabolism*
D011700:Putrescine