Diabetic ketoacidosis associated with olanzapine in an adolescent patient.
Olanzapine (Zyprexa) is an atypical neuroleptic used in adult and pediatric patients for the management of schizophrenia. Common side effects include increased appetite and weight gain. An uncommon but severe adverse effect is the development of diabetic ketoacidosis, reported until now only in adults. We report a case of acute onset diabetic ketoacidosis presenting in a 16-year-old girl during olanzapine therapy.
Selva
K A
KA
Division of Pediatric Endocrinology, University of New Mexico Children's Hospital, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.
Scott
S M
SM
D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines; D016883:Diabetic Ketoacidosis / Q000139:chemically induced*; D005260:Female; D006212:Hallucinations / Q000188:drug therapy; D006801:Humans; D000077152:Olanzapine; D010890:Pirenzepine / Q000009:adverse effects* / Q000031:analogs & derivatives*
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine