title: Inactivation of glutathione peroxidase by NO leads to the accumulation of H2O2 and the induction of HB-EGF via c-Jun NH2-terminal kinase in rat aortic smooth muscle cells.
authors.affiliation: Department of Biochemistry, Osaka University Medical School, Osaka 565-0871, Japan.
authors.forename: Y H
authors.initials: YH
authors.lastname: Koh
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: W
authors.initials: W
authors.lastname: Che
authors.forename: Y S
authors.initials: YS
authors.lastname: Park
authors.forename: Y
authors.initials: Y
authors.lastname: Miyamoto
authors.forename: S
authors.initials: S
authors.lastname: Higashiyama
authors.forename: N
authors.initials: N
authors.lastname: Taniguchi
mesh_terms: D000818:Animals; D001011:Aorta / Q000166:cytology / Q000378:metabolism; D004815:Epidermal Growth Factor / Q000096:biosynthesis* / Q000494:pharmacology; D015971:Gene Expression Regulation, Enzymologic; D005979:Glutathione Peroxidase / Q000037:antagonists & inhibitors*; D066257:Heparin-binding EGF-like Growth Factor; D006861:Hydrogen Peroxide / Q000378:metabolism*; D036341:Intercellular Signaling Peptides and Proteins; D048031:JNK Mitogen-Activated Protein Kinases; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D008954:Models, Biological; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D009569:Nitric Oxide / Q000494:pharmacology*; D051381:Rats; D015398:Signal Transduction; D019014:fas Receptor / Q000187:drug effects
chemical_list: C587885:Hbegf protein, rat; D066257:Heparin-binding EGF-like Growth Factor; D036341:Intercellular Signaling Peptides and Proteins; D019014:fas Receptor; D009569:Nitric Oxide; D004815:Epidermal Growth Factor; D006861:Hydrogen Peroxide; D005979:Glutathione Peroxidase; D048031:JNK Mitogen-Activated Protein Kinases; D020928:Mitogen-Activated Protein Kinases