title: UTP as an extracellular signaling molecule.
abstract: In addition to their central role in many biochemical processes, uridine nucleotides are important extracellular signaling molecules that regulate a broad spectrum of cell functions via activation of P2Y2, P2Y4, and P2Y6 receptors. Cellular release of UTP provides a mechanism for autocrine control of calcium- or protein kinase C-dependent processes.
authors.affiliation: School of Medicine, Department of Medicine, The Cystic Fibrosis Treatment and Research Center, University of North Carolina, Chapel Hill, NC 27599-7248, USA.
authors.forename: E R
authors.initials: ER
authors.lastname: Lazarowski
authors.forename: R C
authors.initials: RC
authors.lastname: Boucher
mesh_terms: D000818:Animals; D005110:Extracellular Space / Q000502:physiology*; D006801:Humans; D015398:Signal Transduction / Q000502:physiology*; D014544:Uridine Triphosphate / Q000502:physiology*
chemical_list: D014544:Uridine Triphosphate