title: Effects of minor constituents (non-glyceride compounds) of virgin olive oil on plasma lipid concentrations in male Wistar rats.
abstract: We aimed to assess the effects of minor constituents (MC) from virgin olive oil upon the plasma lipid profile of experimental animals. Therefore, 32 Wistar rats were fed for 6 weeks with one of four different diets with a similar fatty acid composition but different MC: high-oleic sunflower oil (HOSO), virgin olive oil (VOO), 400%-MC enriched olive oil (EOO) and MC poor (impoverished) olive oil (IOO). At the end of the week 6 of dietary treatment, blood samples were obtained for analysis of lipid composition. A statistically significant influence was observed upon both total HDL (1.593+/-0.4, 1.204+/-0.212, 0.991+/-0.244 and 0.827+/-0.279 mmol/L for EOO, HOSO, VOO and IOO, respectively, Kruskal-Wallis test, P<0.05) and HDL(2)cholesterol levels (1.16+/-0.26, 0.576+/-0.191, 0.585+/-0.216 and 0.583+/-0.207 mmol/L for EOO, HOSO, VOO and IOO, respectively, Kruskal-Wallis test, P<0.05). No statistically significant effect was observed upon LDL-cholesterol or triglycerides. Thus, MC supplementation has beneficial effects on HDL concentrations in Wistar rats.
authors.affiliation: Division of Endocrinology and Clinical Nutrition, Hospitales Universitarios Virgen del Rocío, Seville, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Mangas-Cruz
authors.forename: A
authors.initials: A
authors.lastname: Fernández-Moyano
authors.forename: T
authors.initials: T
authors.lastname: Albi
authors.forename: A
authors.initials: A
authors.lastname: Guinda
authors.forename: F
authors.initials: F
authors.lastname: Relimpio
authors.forename: A
authors.initials: A
authors.lastname: Lanzón
authors.forename: J L
authors.initials: JL
authors.lastname: Pereira
authors.forename: J L
authors.initials: JL
authors.lastname: Serrera
authors.forename: C
authors.initials: C
authors.lastname: Montilla
authors.forename: R
authors.initials: R
authors.lastname: Astorga
authors.forename: P P
authors.initials: PP
authors.lastname: García-Luna
mesh_terms: D000818:Animals; D001835:Body Weight; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000517:prevention & control*; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage*; D008055:Lipids / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood / Q000187:drug effects*; D008297:Male; D000069463:Olive Oil; D010636:Phenols / Q000008:administration & dosage; D010938:Plant Oils / Q000008:administration & dosage* / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D000074242:Sunflower Oil
chemical_list: D005229:Fatty Acids, Monounsaturated; D008055:Lipids; D008075:Lipoproteins, HDL; D000069463:Olive Oil; D010636:Phenols; D010938:Plant Oils; D000074242:Sunflower Oil