Piribedil for restless legs syndrome: a pilot study.
Thirteen consecutive patients with restless legs syndrome (RLS) were treated with piribedil and were rated using an RLS rating scale (0-10) and subjective response (0-100%); 11/13 (85%) had improvement of their mean RLS scores with subjective response ranging from 30% to 100% (mean 74.6%). This pilot study suggests that piribedil is effective for RLS.
Evidente
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St. Luke's Philippine Movement Disorders Center, St. Luke's Medical Center, Quezon City, Philippines. evidente.virgilio@mayo.edu
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018491:Dopamine Agonists / Q000008:administration & dosage* / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D010891:Piribedil / Q000008:administration & dosage* / Q000009:adverse effects; D017448:Receptors, Dopamine D2 / Q000819:agonists; D012148:Restless Legs Syndrome / Q000188:drug therapy*; D016896:Treatment Outcome
D018491:Dopamine Agonists; D017448:Receptors, Dopamine D2; D010891:Piribedil