Functional Changes Of Fetal Muscle Acetylcholine Receptor During Mouse Development.
In developing muscles in vivo and in vitro, the acetylcholine receptor gamma-subunit exists in two splice variants, conferring different single-channel open durations (tau(op)) to reconstituted receptors. In mouse muscles, tau(op) changes around birth, possibly as receptors incorporate either variant of gamma-subunit. This might be relevant to the concomitant maturation of muscle innervation.
Grassi
Francesca
F
Istituto Pasteur-Fondazione Cenci Bolognetti and Dipartimento di Medicina Sperimentale e Patologia, Università di Roma "La Sapienza," Italy.
Eusebi
Fabrizio
F