title: [Efficacy of local ablation therapy for liver metastasis from colorectal cancer--radiofrequency ablation and microwave coagulation therapy].
abstract: We evaluated the efficacy of local ablation therapy in 40 patients with liver metastases from colorectal cancer. Radiofrequency ablation (RFA) and/or microwave coagulation therapy (MCT) were used. Ablation therapies were performed in percutaneous, endoscopic, and operative procedures. The regional recurrence rate at the therapeutic sites was 15% (median follow-up period of 2.5 years). The average surgical margin in the operative ablation group was 11 mm. The cumulative 5-year survival rates were 37% in the local ablation, 41% in the hepatic resection, and 5% in the regional chemotherapy groups. Major complications occurred in only two patients (one biliary fistula and one liver abscess). Together these observations indicate that local ablation therapy is a radical and safe locoregional therapy that provides adequate local control and contributes to long survival.
authors.affiliation: Department of Surgery II, Kumamoto University Medical School, Kumamoto, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Beppu
authors.forename: K
authors.initials: K
authors.lastname: Doi
authors.forename: T
authors.initials: T
authors.lastname: Ishiko
authors.forename: M
authors.initials: M
authors.lastname: Hirota
authors.forename: H
authors.initials: H
authors.lastname: Egami
authors.forename: M
authors.initials: M
authors.lastname: Ogawa
mesh_terms: D017115:Catheter Ablation; D015179:Colorectal Neoplasms / Q000473:pathology*; D004564:Electrocoagulation; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008872:Microwaves / Q000627:therapeutic use*