title: Current efficacy of postexposure prophylaxis against measles with immunoglobulin.
abstract: We assessed results after postexposure prophylaxis against measles with immunoglobulin administered intramuscularly. Children were given 0.33 mL/kg of immunoglobulin from commercially available lots containing various titers of measles antibody within 5 days after exposure. In children receiving immunoglobulin with a titer of < or =16 IU/mL, 57% had clinically evident measles. Immunoglobulin preparations with higher measles antibody titers are required.
authors.affiliation: Division of Pediatrics, Itabashi Ward Medical Association Hospital, Takashimadaira 3-12-6, Itabashi-ku, Tokyo 175-0082, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Endo
authors.forename: H
authors.initials: H
authors.lastname: Izumi
authors.forename: M
authors.initials: M
authors.lastname: Miyashita
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: O
authors.initials: O
authors.lastname: Okubo
authors.forename: K
authors.initials: K
authors.lastname: Harada
mesh_terms: D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007136:Immunoglobulins / Q000008:administration & dosage*; D007223:Infant; D008297:Male; D008457:Measles / Q000276:immunology / Q000517:prevention & control*
chemical_list: D007136:Immunoglobulins