title: Long-term outcome of patients surviving for more than ten years following treatment for acute leukaemia.
abstract: Between 1972 and 1988, 832 consecutive patients were treated for acute leukaemia at St. Bartholomew's Hospital; a retrospective analysis has been conducted to determine the clinical course and outcome for 101 who have survived > or = 10 years following treatment. At a median follow-up of 16 years (range 10-28 years), 86 patients (86 out of 834 total, 11%) were still alive. Long-term follow-up of patients who have survived > or = 10 years following treatment for acute leukaemia revealed that most patients were in normal health, although a significant number of complications had occurred.
authors.affiliation: Department of Medical Oncology, St. Bartholomew's Hospital, London, UK.
authors.forename: I N
authors.initials: IN
authors.lastname: Micallef
authors.forename: A Z
authors.initials: AZ
authors.lastname: Rohatiner
authors.forename: M
authors.initials: M
authors.lastname: Carter
authors.forename: M
authors.initials: M
authors.lastname: Boyle
authors.forename: S
authors.initials: S
authors.lastname: Slater
authors.forename: J A
authors.initials: JA
authors.lastname: Amess
authors.forename: T A
authors.initials: TA
authors.lastname: Lister
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D016026:Bone Marrow Transplantation; D005260:Female; D005298:Fertility; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007938:Leukemia / Q000401:mortality* / Q000601:surgery; D007951:Leukemia, Myeloid / Q000401:mortality / Q000601:surgery; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000401:mortality / Q000601:surgery; D011788:Quality of Life; D012074:Remission Induction; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome