[Mechanisms of development of diabetic macroangiopathy].
Pieces of the aorta and heart coronary arteries taken at autopsy of 100 patients who had died of insulin-dependent and non-insulin-dependent diabetes mellitus were studied histologically and immunohistologically. Atherosclerosis was more pronounced in diabetes mellitus patients than in patients with normal glycemic indices. Atherosclerosis was most severe in non-insulin-dependent diabetes. Diabetic microangiopathy of the vasa vasorum of large arteries promotes development of atherosclerosis.
Saltykov
B B
BB
I. M. Sechenov Moscow Medical Academy, 119881, Moscow.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000209:etiology / Q000473:pathology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000473:pathology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000473:pathology; D003925:Diabetic Angiopathies / Q000209:etiology / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000473:pathology; D008875:Middle Aged