VEB-1-like extended-spectrum beta-lactamases in Pseudomonas aeruginosa, Kuwait.
Two clinical Pseudomonas aeruginosa isolates from patients in intensive care units in Kuwait were resistant to expanded-spectrum cephalosporins and showed a synergistic effect between ceftazidime and clavulanic acid. This is the first report of extended-spectrum enzymes from nosocomial isolates from the Middle East.
Poirel
L
L
Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France.
Rotimi
V O
VO
Mokaddas
E M
EM
Karim
A
A
Nordmann
P
P
D000595:Amino Acid Sequence; D029968:Escherichia coli Proteins; D006801:Humans; D007730:Kuwait; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011550:Pseudomonas aeruginosa / Q000201:enzymology*; D001618:beta-Lactamases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D029968:Escherichia coli Proteins; C119424:beta-lactamase VEB-1, E coli; D001618:beta-Lactamases