Granulomatous kerato-conjunctivitis as a manifestation of Hodgkin lymphoma.
OBJECTIVE
To report atypical kerato-conjunctivitis as a manifestation of Hodgkin disease.


METHODS
Case report.


RESULTS
A 19-year old woman presented with conjunctival nodules and corneal infiltrates. Diffuse lymph node enlargement occurred, but not in the preauricular or submandibular areas. Extensive microbiologic examination was negative. Conjunctival biopsy showed noncaseating granulomas. Inguinal lymph node biopsy showed Hodgkin lymphoma, and chemotherapy was instituted. Ocular signs resolved after 6 weeks, but a corneal scar remained.


CONCLUSIONS
The appearance of conjunctival granulomas and corneal infiltrates may represent a clinical manifestation of Hodgkin lymphoma.
Barkana
Y
Y
Department of Ophthalmology, Assaf Harofe Medical Center, Beer Yaacov, Zerifin, Israel. idityaniv@yahoo.com
Zadok
D
D
Herbert
M
M
Kornberg
A
A
Nemet
P
P
D000328:Adult; D003229:Conjunctival Diseases / Q000209:etiology* / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000209:etiology* / Q000473:pathology; D006689:Hodgkin Disease / Q000150:complications*; D006801:Humans; D007637:Keratoconjunctivitis / Q000209:etiology*