title: [Conceptual basis for defining viral insecticide harmlessness for human health and the environment].
abstract: The qualitative distinction of the new class of virus-based biopesticides from chemicals is the intracellular parasitism of the active agent in the organisms of the living biological host, its capacity to join natural microbiocenoses and to restrain the number of the destructive species over a long period of time. Thus, the program of the study of harmlessness of entomopathogenic viruses must be aimed at preventing the possibility of their adaptation to non-target animals, reproduction and the ability to provoke the non-specific infection. Other parameters such as toxicity and allergenicity of the preparations and their standardization will be investigated under the absence of such ability. The appropriate schemes and methods of investigations have been developed.
authors.affiliation: Kyiv Scientific-Research Institute of Epidemiology and Infectious Diseases, Ministry of Public Health of Ukraine.
authors.forename: V L
authors.initials: VL
authors.lastname: Vasyl'ieva
mesh_terms: D016367:Baculoviridae / Q000472:pathogenicity*; D004782:Environmental Health; D006801:Humans; D010572:Pest Control, Biological