[Functional morphology of the hypophyseal-adrenal-gonad system in different variants of prostatic hyperplasia].
Two forms of prostatic hyperplasia are distinguished: fibro-glandular (FGH) and glandular-fibrous (GFH). An increase in the number of adenohypophysis cells producing gonadotrophic hormone, hyperplasia of the adrenal reticular zone, hyperplasia and hypertrophy of Leydig and Sertoli cells in the testis were observed in FGH. Signs of enhanced functional activity were observed in all cases of hyperplasia. In GFH there was an increase in the number of adenohypophyseal cells producing adrenocorticotrophic hormone, hyperplasia of the fascicular layer in the adrenals, atrophy of Leydig cells in the presence of Sertoli cell hyperplasia. The variant of prostatic hyperplasia is determined by the hormonal changes and this may help in choosing of approaches to therapeutic correction of prostatic hyperplasia and its early diagnosis.
Iushkov
P V
PV
I. M. Sechenov Moscow Medical Academy, 119881, Moscow.
Morozov
A G
AG
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D010913:Pituitary-Adrenal System / Q000473:pathology*; D011470:Prostatic Hyperplasia / Q000473:pathology*; D013737:Testis / Q000473:pathology*