title: Efg1, a morphogenetic regulator in Candida albicans, is a sequence-specific DNA binding protein.
abstract: Efg1 is essential for hyphal development in the human pathogen Candida albicans under most conditions. Efg1 is related to basic helix-loop-helix regulators, and therefore most workers presume that Efg1 is a transcription factor. Here we confirm that Efg1 is a DNA binding protein that can interact specifically with the E box.
authors.affiliation: Department of Molecular and Cell Biology, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, United Kingdom.
authors.forename: P
authors.initials: P
authors.lastname: Leng
authors.forename: P R
authors.initials: PR
authors.lastname: Lee
authors.forename: H
authors.initials: H
authors.lastname: Wu
authors.forename: A J
authors.initials: AJ
authors.lastname: Brown
mesh_terms: D001665:Binding Sites; D002176:Candida albicans / Q000166:cytology* / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D005656:Fungal Proteins; D005800:Genes, Fungal; D011401:Promoter Regions, Genetic; D011485:Protein Binding; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: D004268:DNA-Binding Proteins; C121438:EFG1 protein, Candida albicans; D005656:Fungal Proteins; D014157:Transcription Factors