cAmp signaling cascade: a promising role in ethanol tolerance and dependence.
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Subhash C. Pandey and Toshikazu Saito. The presentations were (1) Action of ethanol on cAMP signaling pathways, by M. Yoshimura; (2) Alterations in the G protein adenylyl cyclase system and their mRNA levels in alcoholics, by H. Sohma; (3) The role of the CREB gene transcription factor in ethanol dependence and preference, by Subhash C. Pandey; and (4) The efficacy of adenylyl cyclase signal transduction to the nucleus in primary alcoholics, by M. E. Götz.
Pandey
S C
SC
University of Illinois Department of Psychiatry, and VA Chicago Health Care System, Chicago, Illinois 60612, USA. scpandey@uic.edu
Saito
T
T
Yoshimura
M
M
Sohma
H
H
Götz
M E
ME
D000437:Alcoholism / Q000378:metabolism; D000818:Animals; D050882:CREB-Binding Protein; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D000242:Cyclic AMP / Q000378:metabolism*; D017868:Cyclic AMP-Dependent Protein Kinases / Q000187:drug effects* / Q000378:metabolism; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D009687:Nuclear Proteins / Q000187:drug effects* / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects* / Q000502:physiology; D015534:Trans-Activators / Q000187:drug effects* / Q000378:metabolism; D014158:Transcription, Genetic / Q000187:drug effects / Q000502:physiology
D002492:Central Nervous System Depressants; D009687:Nuclear Proteins; D015534:Trans-Activators; D000431:Ethanol; D000242:Cyclic AMP; D050882:CREB-Binding Protein; C494363:CREBBP protein, human; D017868:Cyclic AMP-Dependent Protein Kinases