Are women with premenstrual dysphoric disorder prone to osteoporosis?
OBJECTIVE
The objective of this study was to examine whether bone mineral density (BMD) is reduced in women with premenstrual dysphoric disorder (PMDD).


METHODS
Thirty-eight healthy women participated: 20 with prospectively confirmed PMDD and 18 without PMDD. Bone mass was measured using dual-energy x-ray absorptiometry at three sites: lumbar spine anteroposterior, lumber spine lateral, and femoral neck. Results from the PMDD and control groups were compared with each other and with age- and sex-matched normative data.


RESULTS
The BMD of both groups was as expected for their age and sex, and groups did not differ in BMD or Z scores for any of the bone sites studied.


CONCLUSIONS
If women with PMDD are at an increased risk of developing osteoporosis, this risk is not manifested in their BMD.
Halbreich
U
U
BioBehavioral Program, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14215, USA. urielh@acsu.buffalo.edu
Kahn
L S
LS
D000328:Adult; D015519:Bone Density / Q000502:physiology; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology* / Q000523:psychology*; D011293:Premenstrual Syndrome / Q000523:psychology*; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors