title: Metabolic and ethnic determinants of alcohol drinking habits and vulnerability to alcohol-related disorder.
abstract: This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Shoji Harada and Dharam P. Agarwal. The presentations were (1) Mutations in the exons, exon-intron junctions, and promoter regions of human CYP2E1 gene and alcoholism, by Fumio Nomura; (2) Genetic variability in alcohol metabolism and drinking habits in Japanese, by Shoji Harada; (3) Genetic studies of alcohol dependence using alcoholics with inactive ALDH2, by Susumu Higuchi; and (4) Alcohol consumption, apolipoprotein polymorphisms, and cardiovascular disorders, by Dharam P. Agarwal.
authors.affiliation: Institute of Community Medicine (SHa), University of Tsukuba, Tsukuba, Ibaraki, Japan. sjharada@md.tsukuba.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Harada
authors.forename: D P
authors.initials: DP
authors.lastname: Agarwal
authors.forename: F
authors.initials: F
authors.lastname: Nomura
authors.forename: S
authors.initials: S
authors.lastname: Higuchi
mesh_terms: D000428:Alcohol Drinking / Q000235:genetics* / Q000378:metabolism; D019973:Alcohol-Related Disorders / Q000235:genetics* / Q000378:metabolism; D000444:Aldehyde Dehydrogenase / Q000235:genetics* / Q000378:metabolism; D000071396:Aldehyde Dehydrogenase, Mitochondrial; D000818:Animals; D001053:Apolipoproteins / Q000235:genetics* / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000235:genetics / Q000378:metabolism; D019392:Cytochrome P-450 CYP2E1 / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D007564:Japan / Q000208:ethnology; D011110:Polymorphism, Genetic / Q000235:genetics; D044302:Receptor, Serotonin, 5-HT1B; D011985:Receptors, Serotonin / Q000235:genetics
chemical_list: D001053:Apolipoproteins; C470302:HTR1B protein, human; D044302:Receptor, Serotonin, 5-HT1B; D011985:Receptors, Serotonin; D019392:Cytochrome P-450 CYP2E1; C096127:ALDH2 protein, human; D000444:Aldehyde Dehydrogenase; D000071396:Aldehyde Dehydrogenase, Mitochondrial