Dielectrical model of cellular structures in radio frequency and microwave spectrum. Electrically interacting versus noninteracting cells.
A model of dielectrical properties of cellular structures of a tissue has been proposed. Cellular structures were presented as a composition of membrane covered spheres and cylinders that do not interact with each other. No restrictions were applied to the thickness of cellular membranes. The model was further generalized into a case of electrically interacting cells. The difference in dielectrical properties calculated with the model of electrically noninteracting versus interacting cells is inversely dependent on frequency. At biological values of cellular volume fraction near 0.7 (packed configuration) the difference is about 10%-15% in resistance and in epsilon' for frequencies near 0.1 MHz. Experimental data for myocardial tissue and theoretical data, for both interacting and noninteracting models, reasonably agree at frequencies of 1-100 MHz.
Semenov
S Y
SY
Laser and Applied Technologies Laboratory, Carolinas Heart Institute and Carolinas Medical Center, Charlotte, NC 28203-2861, USA. ssemenov@carolinas.org
Simonova
G I
GI
Starostin
A N
AN
Taran
M G
MG
Souvorov
A E
AE
Bulyshev
A E
AE
Svenson
R H
RH
Nazarov
A G
AG
Sizov
Y E
YE
Posukh
V G
VG
Pavlovsky
A
A
Tatsis
G P
GP
D000818:Animals; D001698:Biomedical Engineering; D002462:Cell Membrane / Q000502:physiology; D004285:Dogs; D004553:Electric Conductivity; D004594:Electrophysiology; D005260:Female; D006321:Heart / Q000502:physiology*; D008297:Male; D008872:Microwaves; D008955:Models, Cardiovascular; D011846:Radio Waves