title: [Effects of yinchenhao decoction on normal animals and animal models of diabetes mellitus].
abstract: OBJECTIVE
  To study the effects of yinchenhao Decoction on the blood glucose level in a variety of animal models and its mechanism.
  
  
  METHODS
  Normal mice, rats model of ailoxan (ALX)-induced diabetes mellitus (DM), mice model of ALX-DM and rats model of dexamethasone (DX)-induced insulin resistance (IR) were used.
  
  
  RESULTS
  yinchenhao Decoction was able to inhibit the hyperglycemia by ALX-induced mice(P < 0.01), significantly reduce level of FBG in normal mice, ALX-DM mice and rats (P < 0.05-0.01), improve IGT and lower 2hBG (P < 0.01) after OGTT in DX-induced insulin-resistant rats.
  
  
  CONCLUSIONS
  The results suggest that yinchenhao Decoction possesses similar hypoglycemic action to meftormin and gliclazied.
authors.affiliation: Guangzhou Institute of Traditional Chinese Medicine & Materia Medica, Guangzhou 510130.
authors.forename: J
authors.initials: J
authors.lastname: Pan
authors.forename: C
authors.initials: C
authors.lastname: Han
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.forename: J
authors.initials: J
authors.lastname: Du
authors.forename: A
authors.initials: A
authors.lastname: Li
mesh_terms: D000818:Animals; D019306:Artemisia / Q000737:chemistry; D001786:Blood Glucose / Q000737:chemistry / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D011817:Rabbits; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D001786:Blood Glucose; D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents