Rat lung MRI using low-temperature prepolarized helium-3.
The purpose of this study was to evaluate the recently proposed technique of 3He prepolarization at low temperature and high field (Kober et al. Magn Reson Med 1999; 41:1084-1087) for fast imaging of the lung. Helium-3 was cooled to 2.4 K in a magnetic field of 8 Tesla to obtain a polarization of 0.26%. The polarized 3He was warmed up to room temperature and transferred to a rat, with a final polarization of about 0.1%, large enough for acquiring a 3D image of the rat lung in 30 s.
Kober
F
F
Laboratoire mixte INSERM U438/Université Joseph Fourier: RMN Bioclinique, Laboratoire de Recherche Correspondant du CEA, Grenoble, France.
Wolf
P E
PE
Vermeulen
G
G
Duhamel
G
G
Lamalle
L
L
Leviel
J L
JL
Décorps
M
M
Ziegler
A
A
D000818:Animals; D003080:Cold Temperature; D006371:Helium; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007554:Isotopes; D008168:Lung / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging; D051381:Rats
D007554:Isotopes; D006371:Helium