Apoptosis in the Retina: The Silent Death of Vision.
Pathogenetic mechanisms of retinal degeneration include cell loss by apoptosis. This gene-regulated mode of single-cell death occurs in a number of widespread human diseases such as neurodegeneration. The knowledge of genes and signaling in retinal apoptosis is expanding and opens up therapeutic strategies to ameliorate blinding retinal diseases.
Remé
Charlotte E.
CE
Department of Ophthalmology, University Eye Clinic, Zurich, Switzerland.
Grimm
Christian
C
Hafezi
Farhad
F
Wenzel
Andreas
A
Williams
Theodore P.
TP