Rescue treatment with abciximab in acute ischemic stroke.
In acute ischemic stroke, reocclusion after an initially successful thrombolysis treatment can occur and is associated with increased morbidity and mortality. The authors present the successful use of abciximab, a platelet glycoprotein IIb/IIIa receptor inhibitor, in a patient with a thrombotic occlusion of the proximal middle cerebral artery, which was refractory to combined IV and intra-arterial thrombolysis and percutaneous intracranial balloon angioplasty.
Lee
K Y
KY
Departmens of Neurology, Yonsei University College of Medicine, Seoul, Korea.
Heo
J H
JH
Lee
S I
SI
Yoon
P H
PH
D000077284:Abciximab; D000208:Acute Disease; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D000925:Anticoagulants / Q000008:administration & dosage*; D002545:Brain Ischemia / Q000175:diagnosis / Q000628:therapy*; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000008:administration & dosage*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020521:Stroke / Q000175:diagnosis / Q000628:therapy*; D015912:Thrombolytic Therapy
D000911:Antibodies, Monoclonal; D000925:Anticoagulants; D007140:Immunoglobulin Fab Fragments; D000077284:Abciximab