title: Intervertebral disc lesions in diffuse idiopathic skeletal hyperostosis (DISH).
abstract: OBJECTIVE
  In order to evaluate the relationships between DISH and vertebral osteochondrosis (degenerative disc disease), the radiographs of the spine of 69 DISH patients were compared to those of 68 controls.
  
  
  METHODS
  Radiographs of 69 patients affected by DISH according to Resnick's criteria and of 68 control subjects affected by diseases other than DISH, were evaluated in order to determine the prevalence of vertebral osteochondrosis, diagnosed by the occurrence of moderate to severe reduction in the intervertebral disc height and of the extensive radiographic changes typical of degenerative disc disease, including vacuum phenomena and vertebral body marginal sclerosis. The rate ratios with 95% confidence intervals were computed, with stratification by age groups.
  
  
  RESULTS
  Thirty-eight DISH patients (55.1%) and 34 controls (50%) showed vertebral osteochondrosis. Stratification by age revealed an increased prevalence of vertebral osteochondrosis in younger DISH patients with respect to controls (p < 0.05).
  
  
  CONCLUSIONS
  Our results show that vertebral osteochondrosis may be associated with DISH and underline the differences between classification and diagnostic criteria. Moreover, it could be hypothesized that DISH plays a predisposing role in the development of vertebral osteochondrosis during the early stages of the disease, causing an early modification in the physiological curves of the spine.
authors.affiliation: Rehabilitation Unit, Salvatore Maugeri Foundation I.R.C.C.S., Medical Centre of Campoli MT-Telese, BN, Italy. cardigi@tin.it
authors.forename: C
authors.initials: C
authors.lastname: di Girolamo
authors.forename: N
authors.initials: N
authors.lastname: Pappone
authors.forename: C
authors.initials: C
authors.lastname: Rengo
authors.forename: E
authors.initials: E
authors.lastname: Miniero
authors.forename: C
authors.initials: C
authors.lastname: Crisci
authors.forename: I
authors.initials: I
authors.lastname: Olivieri
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D005260:Female; D006801:Humans; D004057:Hyperostosis, Diffuse Idiopathic Skeletal / Q000453:epidemiology* / Q000473:pathology*; D007403:Intervertebral Disc / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence