title: Automation and high through-put for a DNA database laboratory: development of a laboratory information management system.
abstract: Automation and high through-put production of DNA profiles has become a necessity in every DNA database unit. In our laboratory we developed a Laboratory Information Management System (LIMS) controlled workflow architecture, which comprises a robotic DNA extraction- and pipetting-system and a capillary electrophoresis unit. This allows a through-put of 4,000 samples per person per year. Improved sample handling and data management, full sample- and batch-histories, and software-aided supervision of result data, with a consequent average turn-around time of 8 days, are the main features of our new system.
authors.affiliation: Institute of Legal Medicine, University of Innsbruck, Muellerstrasse 44, A-6020 Innsbruck, Austria. martin.steinlechner@uibk.ac.at
authors.forename: M
authors.initials: M
authors.lastname: Steinlechner
authors.forename: W
authors.initials: W
authors.lastname: Parson
mesh_terms: D001317:Austria; D002984:Clinical Laboratory Information Systems / Q000592:standards*; D016172:DNA Fingerprinting / Q000379:methods*; D003628:Database Management Systems / Q000592:standards*; D001330:Electronic Data Processing / Q000379:methods*; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D012680:Sensitivity and Specificity