title: Randomized controlled evaluation of non-surgical treatments for temporomandibular joint anterior disk displacement without reduction.
abstract: The common methods for treating anterior disk displacement without reduction (ADDwor) are not based on randomized controlled clinical trials. Our study evaluated non-surgical treatments in 69 MRI-confirmed ADDwor subjects (m/f = 6/63). Subjects were randomly assigned to a control group and one of two treatment groups. Outcomes included maximum mouth opening, visual analogue scale of pain, and daily activity limitation. Calibrated examiners collected data at the initial interview and at 0, 2, 4, and 8 weeks of treatment. At the eight-week point, within-group improvements were present for all variables, for all groups. Between-group differences were not highly evident, with only mean daily activity limitation for the self-care/NSAID group being significantly lower than that of the occlusal appliance/jaw mobilization + self-care/NSAID group at the two- and four-week time-points. These results suggest that ADDwor subjects will improve with only minimal treatment intervention, and no significant difference was evident for the treatments tested and the control condition.
authors.affiliation: Department of Fixed Prosthodontics, Okayama University Dental School, Japan. hajime@md.okayama-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Minakuchi
authors.forename: T
authors.initials: T
authors.lastname: Kuboki
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuka
authors.forename: K
authors.initials: K
authors.lastname: Maekawa
authors.forename: H
authors.initials: H
authors.lastname: Yatani
authors.forename: A
authors.initials: A
authors.lastname: Yamashita
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000704:Analysis of Variance; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003768:Dental Occlusion, Centric; D004008:Diclofenac / Q000627:therapeutic use; D005081:Exercise Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D004204:Joint Dislocations / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008334:Mandible / Q000503:physiopathology; D008409:Mastication / Q000502:physiology; D009068:Movement; D017090:Occlusal Splints; D010147:Pain Measurement; D016059:Range of Motion, Articular / Q000502:physiology; D012648:Self Care; D018709:Statistics, Nonparametric; D013704:Temporomandibular Joint / Q000503:physiopathology; D019224:Temporomandibular Joint Disc / Q000503:physiopathology*; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac