title: Physiology of Receptor-Mediated Lymphocyte Apoptosis.
abstract: Apoptosis (programmed cell death), a physiological mechanism eliminating abundant and potentially harmful cells, is triggered by a variety of stimuli including activation of distinct receptors. The machinery mediating CD95 receptor-induced apoptosis includes caspases, ceramide, kinases, Ras and Rac, formation of O(2)(-), mitochondrial proteins, inhibition of K(+) channels, activation of Cl(-) channels, and osmolyte release.
authors.affiliation: Department for Physiology of the University of Tübingen, Gmelinstrasse 5, D-72076 Tübingen, Germany.
authors.forename: F.
authors.initials: F
authors.lastname: Lang
authors.forename: I.
authors.initials: I
authors.lastname: Szabo
authors.forename: A.
authors.initials: A
authors.lastname: Lepple-Wienhues
authors.forename: D.
authors.initials: D
authors.lastname: Siemen
authors.forename: E.
authors.initials: E
authors.lastname: Gulbins