A case of splenic abscess due to Chlamydia pneumoniae.
In this report, a case of chlamydial disease with splenic abscess associated with Chlamydia pneumoniae antigen and antibody was described. On spleen biopsy of the patient, an antigen specific to C.pneumoniae was detected by immunofluorescence staining with a monoclonal antibody. Serologic studies revealed a high antibody titer to C.pneumoniae in sera collected from the patient and her husband. Treatment with the antibiotic minocycline improved her condition.
Bessho
H
H
Department of Microbiology, Kawasaki Medical School, 701-0192, Kurashiki, Japan. bessho@bcc.kawasaki-m.ac.jp
Ichihara
I
I
Takii
M
M
D018784:Abdominal Abscess / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000097:blood / Q000276:immunology; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial / Q000097:blood / Q000276:immunology; D001706:Biopsy; D023521:Chlamydophila Infections / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000627:therapeutic use; D013154:Spleen / Q000382:microbiology* / Q000473:pathology
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D007106:Immune Sera; D008911:Minocycline