Intracellular localization of VAMP-1 protein in human neutrophils.
We studied the intracellular localization of vesicle-associated membrane protein VAMP-1 in human neutrophils. VAMP-1 was associated with membranes of gelatinase and specific secretory granules rapidly mobilized during exocytosis. VAMP-1 probably acts as a component of the SNARE complex during exocytosis of gelatinase and specific granules in human neutrophils.
Nabokina
S M
SM
Biological Department, N. P. Ogarev Mordvinian State University, Saransk.
D000818:Animals; D002458:Cell Fractionation; D002462:Cell Membrane / Q000737:chemistry; D005089:Exocytosis; D006801:Humans; D015151:Immunoblotting; D008565:Membrane Proteins / Q000032:analysis*; D009504:Neutrophils / Q000737:chemistry* / Q000166:cytology; D050683:R-SNARE Proteins; D022142:Secretory Vesicles / Q000737:chemistry*
D008565:Membrane Proteins; D050683:R-SNARE Proteins