title: Prognostic factors for survival in invasive squamous cell vulvar carcinoma: a univariate analysis.
abstract: The charts of 50 women with invasive squamous cell vulvar carcinoma were reviewed retrospectively, and pathologic, medical and life style factors were analyzed for their possible influence on survival using the Cox regression univariate model. The median age of the cohort was 73.5 years. The patient distribution according to stage was as follows: stage I: 17; stage II: 16; stage III: 12, and stage IVa: 5 patients. The median follow-up was 61 months. The univariate analysis revealed that the overall survival was decreased by age > or = 73.5 years (p = 0.0185), advanced stage (p = 0.0026), grade III differentiation (p < 0.0001), ulcerative type of the tumor (p = 0.0055), tumor diameter >40 mm (p = 0.0053), obesity (p = 0.011), smoking (p = 0.0177), diabetes (p = 0.0122) and hypertension (p = 0.044), but not with clitoral involvement.
authors.affiliation: Department of Radiation Oncology, Aretaieion Hospital, Athens University, Greece. jrkouv@otenet.gr
authors.forename: J
authors.initials: J
authors.lastname: Kouvaris
authors.forename: V
authors.initials: V
authors.lastname: Kouloulias
authors.forename: C
authors.initials: C
authors.lastname: Loghis
authors.forename: C
authors.initials: C
authors.lastname: Sykiotis
authors.forename: M
authors.initials: M
authors.lastname: Balafouta
authors.forename: L
authors.initials: L
authors.lastname: Vlahos
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D018307:Neoplasms, Squamous Cell / Q000401:mortality* / Q000473:pathology; D011379:Prognosis; D012306:Risk; D012907:Smoking / Q000009:adverse effects; D015996:Survival Rate; D014846:Vulvar Neoplasms / Q000401:mortality* / Q000473:pathology