title: Detection of isolated distant metastasis in soft tissue sarcoma by fluorodeoxyglucose positron emission tomography: case report.
abstract: Fluorodeoxyglucose (FDG), labeled with F-18, is a glucose analog that accumulates in cells in proportion to the rate of glucose metabolism, and increased carbohydrate metabolism has been recognized as a feature of malignant cells versus normal cells. In addition, it permits the detection of metastases not discovered by bone scan. Although detection of the primary site of disease is usually accomplished well with conventional techniques, the performance of FDG positron emission tomography (PET) may be useful to determine metastases that are not clinically evident. The authors describe a case of early detection of distant metastases by FDG-PET in a young patient diagnosed with rhabdomyosarcoma of the hand.
authors.affiliation: Department of Pediatric Hemato-Oncology, Rambam Medical Center, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. m_benarush@rambam.health.gov.il
authors.forename: M W
authors.initials: MW
authors.lastname: Ben Arush
authors.forename: O
authors.initials: O
authors.lastname: Israel
authors.forename: Z
authors.initials: Z
authors.lastname: Kedar
authors.forename: L
authors.initials: L
authors.lastname: Goralnik
authors.forename: L A
authors.initials: LA
authors.lastname: Best
authors.forename: N
authors.initials: N
authors.lastname: Meushar
authors.forename: R
authors.initials: R
authors.lastname: Elhasid
authors.forename: S
authors.initials: S
authors.lastname: Postovsky
mesh_terms: D000293:Adolescent; D001132:Arm / Q000473:pathology; D003131:Combined Modality Therapy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006225:Hand / Q000473:pathology; D006801:Humans; D011877:Radionuclide Imaging; D018233:Rhabdomyosarcoma, Embryonal / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D012509:Sarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000556:secondary*
chemical_list: D019788:Fluorodeoxyglucose F18