title: Toxic megacolon in a renal allograft recipient with cytomegalovirus colitis.
abstract: We report a 35-year-old man, a renal allograft recipient, who presented with toxic megacolon. Segmental biopsies from the colon were consistent with cytomegalovirus colitis. Serum polymerase chain reaction for cytomegalovirus DNA confirmed the diagnosis. He was treated with ganciclovir but, though his abdominal condition improved initially, he worsened later and succumbed to his illness.
authors.affiliation: Department of Gastrointestinal Sciences and Wellcome Research Laboratory, Christian Medical College and Hospital, Vellore. ashis@angelfire.com
authors.forename: A
authors.initials: A
authors.lastname: Mukhopadhya
authors.forename: S C
authors.initials: SC
authors.lastname: Samal
authors.forename: S
authors.initials: S
authors.lastname: Patra
authors.forename: C E
authors.initials: CE
authors.lastname: Eapen
authors.forename: A
authors.initials: A
authors.lastname: Abraham
authors.forename: P P
authors.initials: PP
authors.lastname: Thomas
authors.forename: G M
authors.initials: GM
authors.lastname: Chandy
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D004279:DNA, Viral / Q000097:blood; D017809:Fatal Outcome; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008532:Megacolon, Toxic / Q000821:virology*; D016133:Polymerase Chain Reaction
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D015774:Ganciclovir