title: Transpupillary thermotherapy of subfoveal occult choroidal neovascularization.
abstract: Choroidal neovascularization secondary to age-related macular degeneration is a leading cause of vision loss in adults. Although most patients present with occult CNV, treatment has focused on the small percentage of eyes with well-delineated, classic CNV. Transpupillary thermotherapy is a recent advancement in the management of occult CNV. Transpupillary thermotherapy acts in a subthreshold manner by slightly raising the choroidal temperature. A recent pilot study demonstrated that 56% of treated eyes remained stable one year after treatment with only 25% losing two lines of visual acuity. The TTT4CNV study will further evaluate the effectiveness of transpupillary thermotherapy in a randomized, double-blind trial.
authors.affiliation: New England Eye Center, Tufts University School of Medicine, Boston, Massachusetts, USA.
authors.forename: A H
authors.initials: AH
authors.lastname: Rogers
authors.forename: E
authors.initials: E
authors.lastname: Reichel
mesh_terms: D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D005451:Fluorescein Angiography; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007368:Interferometry; D008027:Light; D008268:Macular Degeneration / Q000150:complications; D011680:Pupil; D014054:Tomography