Y chromosome-specific short tandem repeats in forensic casework.
Several case examples are presented to illustrate the usefulness of Y chromosome specific human DNA markers in a forensic setting. The markers used are the tetrameric short tandem repeats (STR's) DYS19, DYS389I, DYS389II, and DYS390. The main advantage of the Y-STR approach is the ability to detect the male component in a mixture of male and female DNA. It is also useful for the determination of the number of semen donors for mixtures of two or more male individuals.
Prinz
M
M
Department of Forensic Biology, Office of Chief Medical Examiner, 520 First Ave, New York, NY 10016, USA. prinzm01@popmail.med.nyu.edu
Sansone
M
M
D016172:DNA Fingerprinting / Q000379:methods*; D005260:Female; D005554:Forensic Medicine / Q000379:methods; D006801:Humans; D008297:Male; D011902:Rape; D012463:Saliva / Q000737:chemistry; D012661:Semen / Q000737:chemistry*; D012680:Sensitivity and Specificity; D020080:Tandem Repeat Sequences; D014626:Vaginal Smears; D014998:Y Chromosome / Q000235:genetics*