title: Ion Permeability of the Nuclear Envelope.
abstract: The nuclear envelope mediates nucleocytoplasmic communication. Nuclear pores transport proteins and RNA into and out of the nucleus. The pore is believed to allow free ion diffusion. Using an electrophysiological approach, we show the possible semipermeable properties of the envelope. To accomplish these functions we hypothesize a mechanism in which the pore complex acts as a molecular diaphragm.
authors.affiliation: Dipartimento di Fisiologia e Biochimica Generali, Laboratorio di Elettrofisiologia, Universita degli Studi di Milano, via Celoria 26, I-20133 Milan, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Mazzanti