title: Rupture of an unscarred uterus with misoprostol induction: case report and review of the literature.
abstract: Uterine rupture is a serious and often tragic complication that is life threatening to both mother and child. It occurs at a frequency of around 1% in patients with a previously scarred uterus. Rupture of an unscarred uterus is an unexpected and devastating complication of pregnancy. With the increased use of misoprostol as a labor-inducing agent, cases of rupture of an unscarred uterus following its use have been published in the literature. We report a case of uterine rupture in a multigravid woman with an intrauterine fetal death at 29 weeks' gestation whose labor was induced with misoprostol. A review of all cases of uterine rupture with misoprostol induction is also included. Excessive doses of misoprostol should be used with extreme caution in multiparous women and in patients with a previously scarred uterus even in the context of intrauterine fetal death or termination of pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, American University of Beirut, Medical Center, Lebanon.
authors.forename: A Y
authors.initials: AY
authors.lastname: Khabbaz
authors.forename: I M
authors.initials: IM
authors.lastname: Usta
authors.forename: M I
authors.initials: MI
authors.lastname: El-Hajj
authors.forename: A
authors.initials: A
authors.lastname: Abu-Musa
authors.forename: M
authors.initials: M
authors.lastname: Seoud
authors.forename: A H
authors.initials: AH
authors.lastname: Nassar
mesh_terms: D000328:Adult; D005260:Female; D005313:Fetal Death; D006801:Humans; D015160:Hydrops Fetalis; D007231:Infant, Newborn; D007751:Labor, Induced; D008297:Male; D016595:Misoprostol / Q000009:adverse effects*; D010120:Oxytocics / Q000009:adverse effects*; D010298:Parity; D011247:Pregnancy; D014597:Uterine Rupture / Q000139:chemically induced*
chemical_list: D010120:Oxytocics; D016595:Misoprostol