title: An evaluation of the intraoperative transit time measurements of coronary bypass flow.
abstract: OBJECTIVE
  The intraoperative measurement of the coronary bypass flow enables the identification of technical errors while the sternum is still open. The transit-time flow method is able to effectively measure the internal thoracic artery graft flow. The aim of the present study was to analyze the factors which affected the bypass flow rate.
  
  
  METHODS
  We measured the blood flow of 291 in situ internal thoracic artery (ITA) and 190 saphenous vein (SV) grafts constructed in 171 patients undergoing coronary artery bypass grafting from December 1996 to March 2000 using this method during the surgery. All patients underwent postoperative coronary angiography before the patients were discharged. The blood flow rate of all bypass grafts constructed was assessed after the patients were weaned from cardiopulmonary bypass.
  
  
  RESULTS
  The mean flow rate of all ITA grafts was 65.1+/-36.7 ml/min and that of all SV grafts was 56.4+/-29.9 ml/min. According to analyses using correlation tests, the graft flow was found to significantly correlate with the grafted perfusion areas and the diameter of the bypassed coronary arteries. However, no significant difference was observed between the flow rates of the ITA grafts with and without stenosis or string phenomenon, but significant (P<0.0001) correlation was observed between the occurrence of a string sign and the degree of proximal stenosis of the recipient coronary artery. Regarding SV grafts, the mean flow rate of occluded grafts (29.2+/-20.5 ml/min) was significantly (P<0.0001) less than non-occluded grafts (56.4+/-29.9 ml/min).
  
  
  CONCLUSIONS
  The bypass flow was affected by such a large number of factors that only measuring the bypass flow rate could not sufficiently predict either stenosed or narrowed grafts. However, ITA grafts bypassed to the coronary arteries with less stenosis were shown to more easily become narrowed.
authors.affiliation: Department of Cardiovascular Surgery, Tokyo Saiseikai Central Hospital, 1-4-17 Mita, Minato-ku, 108-0073, Tokyo, Japan. hero.takashi@nifty.ne.jp
authors.forename: T
authors.initials: T
authors.lastname: Hirotani
authors.forename: T
authors.initials: T
authors.lastname: Kameda
authors.forename: S
authors.initials: S
authors.lastname: Shirota
authors.forename: Y
authors.initials: Y
authors.lastname: Nakao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003326:Coronary Circulation; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008323:Mammary Arteries / Q000637:transplantation; D008875:Middle Aged; D012501:Saphenous Vein / Q000637:transplantation; D014654:Vascular Patency