title: [Schizencephaly: report of eleven cases].
abstract: A retrospective study comparing clinical and computerized tomography (CT) in 11 patients diagnosed as having schizencephaly was conducted. Seven of these patients were girls and four boys. Six of them had tetraparesis, three hemiparesis and one no motor deficits. Six had epilepsy and ten developmental delay. On CT examinations, 7 patients were found as having bilateral clefts and four unilateral defect. Eight had opened lip clefts and four had a closed lip defect. The commonest associated anomaly was an absent septum pellucidum (n=9), followed by subependymal nodules (n=4), hydrocephalus (n=2) and microcephaly (n=1). Despite magnetic resonance image is the gold-standard to diagnose neuronal migration anomalies, CT can be useful in showing typical aspects of schizencephaly.
authors.affiliation: Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, Paraná, Brasil.
authors.forename: J G
authors.initials: JG
authors.lastname: Amaral
authors.forename: R H
authors.initials: RH
authors.lastname: Yanaga
authors.forename: H J
authors.initials: HJ
authors.lastname: Geissler
authors.forename: A
authors.initials: A
authors.lastname: de Carvalho Neto
authors.forename: I
authors.initials: I
authors.lastname: Bruck
authors.forename: S A
authors.initials: SA
authors.lastname: Antoniuk
mesh_terms: D000293:Adolescent; D001921:Brain / Q000002:abnormalities* / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed