title: Pathogenicity of a bovine viral diarrhoea virus strain in pregnant sows: short communication.
abstract: The biological properties of bovine viral diarrhoea virus (BVDV) strain Oregon C24V were studied after intranasal and subcutaneous infection of pregnant sows. This virus strain is widely used in Hungary for immunising cattle against bovine viral diarrhoea (BVD). Based upon the results of the clinical, gross pathological, histopathological and virological examinations it can be established that the given strain caused asymptomatic infection and serological conversion in sows that were in the second third of gestation. The virus caused clinically apparent disease in some of the piglets born at term, which indicates that it had crossed the placenta. More than half (57%) of the live-born piglets died within 60 days of birth. The sows and their progeny did not shed the virus. BVDV infection has great differential diagnostic importance in pigs, as classical swine fever (CSF) virus strains of reduced virulence cause similar clinical symptoms and gross and histopathological changes.
authors.affiliation: State Control Institute for Veterinary Biologicals, Drugs and Feeds, H-1415 Budapest 10, P.O. Box 318, Hungary. kulcsar@oai.hu
authors.forename: G
authors.initials: G
authors.lastname: Kulcsár
authors.forename: P
authors.initials: P
authors.lastname: Soós
authors.forename: L
authors.initials: L
authors.lastname: Kucsera
authors.forename: R
authors.initials: R
authors.lastname: Glávits
authors.forename: V
authors.initials: V
authors.lastname: Pálfi
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000821:virology*; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000472:pathogenicity*; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000662:veterinary* / Q000821:virology; D013552:Swine; D013553:Swine Diseases / Q000821:virology*