title: An unusual presentation of extramedullary plasmacytoma occurring sequentially in the testis, subcutaneous tissue, and heart.
abstract: Extramedullary plasmacytoma (EMP) is a rare neoplasm of soft tissue that usually arises in the respiratory tract, nasal cavity, sinuses, and nasopharynx. It is even more uncommon for it to arise either in the testis or heart. We report the presentation of a case where plasmacytomas were found sequentially in the testis, subcutaneous tissue, and heart. EMP usually has a good prognosis except when it involves the heart. Our patient survived for only 15 months post autologous hematopoietic stem cell transplantation.
authors.affiliation: Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Nova Scotia, Canada. lfernand@IS.Dal.ca
authors.forename: L A
authors.initials: LA
authors.lastname: Fernandez
authors.forename: S
authors.initials: S
authors.lastname: Couban
authors.forename: R
authors.initials: R
authors.lastname: Sy
authors.forename: R
authors.initials: R
authors.lastname: Miller
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000008:administration & dosage; D018450:Disease Progression; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D010954:Plasmacytoma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000556:secondary*; D013479:Superior Vena Cava Syndrome / Q000209:etiology; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery; D014683:Vena Cava, Superior / Q000473:pathology; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D003907:Dexamethasone; D004317:Doxorubicin