title: Supported liquid membrane stability in chiral resolution by chemically and physically modified membranes.
abstract: In the present work some stability studies on Supported Liquid Membranes (SLMs) to be used for chiral separations were realized. In particular, primary aim was to determine how a modification of the support surface influences the SLM stability. First, the procedure for support modification was optimised, making a screening of various compounds (sulphuric acid, nitric acid, chromic acid, sodium dodecyl sulphate (SDS), glycerol, oleic alcohol, propylene glycol (PPG), bovine serum albumin (BSA)) and testing their performance by means of contact angle measurements. Next, a second screening was realized by permeation tests in a stirred cell. Finally, to compare the stability of modified with unmodified support in a process of interest for chemical and/or biochemical industries, some permeation tests for resolution of DNB-DL-Leucine were realized in a re-circulation system. Results showed a better surface hydrophilization of chemically modified support and better stability of the sulphonated support. However, in operating conditions a little high stability of the unmodified support was obtained.
authors.affiliation: Department of Chemical and Materials Engineering, University of Calabria Via P. Bucci, I-87030 Rende (CS), Italy. r.molinari@unical.it
authors.forename: R
authors.initials: R
authors.lastname: Molinari
authors.forename: P
authors.initials: P
authors.lastname: Argurio
mesh_terms: D005374:Filtration; D007930:Leucine / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D008567:Membranes, Artificial; D009579:Nitrobenzoates / Q000737:chemistry / Q000302:isolation & purification; D009930:Organic Chemicals / Q000737:chemistry* / Q000302:isolation & purification; D010539:Permeability; D012996:Solutions; D013237:Stereoisomerism
chemical_list: D008567:Membranes, Artificial; D009579:Nitrobenzoates; D009930:Organic Chemicals; D012996:Solutions; C051872:N-(3,5-dinitrobenzoyl)leucine; D007930:Leucine