Local vs systemic corticosteroids in the treatment of carpal tunnel syndrome.
The authors compared the effectiveness of low-dose, short-term oral prednisolone vs local methylprednisolone injection in a prospective, double-blinded, parallel treatment study of carpal tunnel syndrome (CTS). A single injection of 15 mg methylprednisolone resulted in significant improvement in global symptom scores over a 12-week period. This study demonstrated the superiority of local steroid injection to oral steroid in the treatment of CTS.
Wong
S M
SM
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, China. jsmwong@hkstar.com
Hui
A C
AC
Tang
A
A
Ho
P C
PC
Hung
L K
LK
Wong
K S
KS
Kay
R
R
Li
E
E
D000284:Administration, Oral; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D002349:Carpal Tunnel Syndrome / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage*; D011446:Prospective Studies
D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D008775:Methylprednisolone