Developing a strategy for the rapid identification of genetically altered mice: an olfactory system perspective.
The mouse genome contains a wide array of uncharacterized genes that are involved in olfactory system development and cellular function. The author describes how random mutagenesis of these genes combined with rapid screening techniques afford the identification of the particular olfactory-related genes that have been altered.
Youngentob
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SL
Department of Neuroscience and Physiology, SUNY Upstate Medical University, Institute for Human Performance, 750 East Adams St., Syracuse, NY 13210, USA.
D000818:Animals; D001522:Behavior, Animal; D051379:Mice; D008817:Mice, Mutant Strains; D016296:Mutagenesis; D009812:Odorants; D010641:Phenotype; D012903:Smell / Q000235:genetics*