Redistribution of gastric Helicobacter pylori after surgery for duodenal ulcer.
OBJECTIVE
To study the distribution of H. pylori in the stomach before and after truncal vagotomy and drainage (TV + D) for chronic duodenal ulcer.


METHODS
Twenty two consecutive patients studied prospectively. H. pylori positivity detected by urease test and histology (Giemsa stain). One or both tests positive indicated positive H. pylori status. Biopsies taken from antrum, body, fundus and stoma (postoperatively) to document H. pylori status before and 6 months after TV + D.


RESULTS
Antral prevalence of H. pylori significantly decreased after surgery while fundal colonization significantly increased. No change was seen in body of stomach.


CONCLUSIONS
There is significant redistribution of H. pylori after TV + D. This has important diagnostic implications in evaluation of postoperative symptoms.
Bangi
A K
AK
Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry-605 006, India.
Kate
V
V
Ananthakrishnan
N
N
Badrinath
S
S
Ratnakar
C
C
D004322:Drainage; D004381:Duodenal Ulcer / Q000382:microbiology / Q000601:surgery*; D016481:Helicobacter Infections / Q000382:microbiology*; D016480:Helicobacter pylori; D006801:Humans; D011184:Postoperative Period; D011446:Prospective Studies; D013270:Stomach / Q000382:microbiology*; D015167:Vagotomy, Truncal