title: [Pathogenesis of acute encephalopathy with shock syndrome].
abstract: We presented 3 cases who exhibited important clinical or histopathological findings relevant to the pathogenesis of acute encephalopathy with shock syndrome (AESS). Hyperpermeability of the blood vesseles in the central nervous system was revealed by autopsy in case 1 and by enhancement CT scan in case 2, which implicated that the primary lesion of AESS was vascular damage. Although other cytokines than interleukin (IL)-6 were not evaluated, high value of IL-6 in case 3 might suggest that the some highly activated cytokines caused AESS.
authors.affiliation: Division of Pediatric Neurology, Yokohama Ryouikuen, Yokohama.
authors.forename: S
authors.initials: S
authors.lastname: Kimura
authors.forename: N
authors.initials: N
authors.lastname: Ohtsuki
authors.forename: A
authors.initials: A
authors.lastname: Nezu
mesh_terms: D000208:Acute Disease; D001927:Brain Diseases / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D012769:Shock / Q000209:etiology*; D013577:Syndrome