title: L1-like non-LTR retrotransposons in the yeast Candida albicans.
abstract: Non-LTR retrotransposons (also known as LINEs) have had a major influence on the structure of many eukaryote genomes. They are abundant in many multicellular eukaryotes, including mammals, but appear to be absent from the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. This absence has, to date, precluded the development of a yeast model system for the study of non-LTR retrotransposons. In this report we describe several families of non-LTR retrotransposons from the yeast Candida albicans. These elements, which we call Zorro elements, are all members of the L1 clade of non-LTR retrotransposons. Some are intact, transcriptionally active and have transposed recently. This finding should allow the development of a yeast model system.
authors.affiliation: Department of Biochemistry, University of Otago, Cumberland Street, P.O. Box 56, Dunedin, New Zealand. timg@sanger.otago.ac.nz
authors.forename: T J
authors.initials: TJ
authors.lastname: Goodwin
authors.forename: J E
authors.initials: JE
authors.lastname: Ormandy
authors.forename: R T
authors.initials: RT
authors.lastname: Poulter
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D015139:Blotting, Southern; D002176:Candida albicans / Q000235:genetics*; D017124:Conserved Sequence; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D019143:Evolution, Molecular; D018628:Gene Dosage; D020084:Long Interspersed Nucleotide Elements / Q000235:genetics*; D016366:Open Reading Frames / Q000235:genetics; D010802:Phylogeny; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D013995:Time; D015534:Trans-Activators; D014158:Transcription, Genetic / Q000235:genetics*; D015533:Transcriptional Activation / Q000235:genetics*
chemical_list: D015534:Trans-Activators; D004247:DNA