Triterpenoid acids from Schisandra propinqua with cytotoxic effect on rat luteal cells and human decidual cells in vitro.
Three triterpenoid acids, nigranoic acid (1), manwuweizic acid (2), schisandronic acid (3), and other four compounds were isolated from the stems of Schisandra propinqua. Compounds 1 and 2 showed significant cytotoxic effect against human decidual cells and rat luteal cells in vitro.
Chen
Y G
YG
Department of Chemistry, Yunnan Normal University, Kunming, 650092, Yunnan, PR China. ygchen48@hotmail.com
Qin
G W
GW
Cao
L
L
Leng
Y
Y
Xie
Y Y
YY
D000818:Animals; D002478:Cells, Cultured / Q000187:drug effects; D003656:Decidua / Q000166:cytology / Q000187:drug effects*; D005260:Female; D006801:Humans; D008184:Luteal Cells / Q000166:cytology / Q000187:drug effects*; D019684:Magnoliopsida; D010936:Plant Extracts / Q000494:pharmacology; D018547:Plant Stems; D010946:Plants, Medicinal; D011247:Pregnancy; D051381:Rats; D017207:Rats, Sprague-Dawley; D014315:Triterpenes / Q000494:pharmacology*
D010936:Plant Extracts; D014315:Triterpenes; C100860:nigranoic acid; C431923:manwuweizic acid; C431924:schisandronic acid