title: SCFAs: The Enigma of Weak Electrolyte Transport in the Colon.
abstract: Short-chain fatty acids are the predominant luminal anions in the colon (>75 mM) and thus create a rather unique environment for transporting epithelium. The colon absorbs short-chain fatty acids, either by diffusion of the protonated species across the apical membrane or by an anion exchange process with bicarbonate. Additionally, short-chain fatty acids modulate Na absorption, Cl secretion, intracellular pH, and cell volume.
authors.affiliation: University of Texas Medical School at Houston, PO Box 20708, Houston, TX 77225, USA.
authors.forename: Joseph H.
authors.initials: JH
authors.lastname: Sellin