Up-regulation of prosaposin by the retinoid HPR and its effect on ceramide production and integrin receptors.
Panigone
S
S
Department of Experimental Oncology, Istituto Nazionale Tumori, 20133 Milano, Italy.
Bergomas
R
R
Fontanella
E
E
Prinetti
A
A
Sandhoff
K
K
Grabowski
G A
GA
Delia
D
D
D000970:Antineoplastic Agents / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002518:Ceramides / Q000096:biosynthesis*; D017313:Fenretinide / Q000494:pharmacology*; D015972:Gene Expression Regulation, Neoplastic; D006023:Glycoproteins / Q000096:biosynthesis*; D016023:Integrins / Q000378:metabolism*; D008954:Models, Biological; D018384:Oxidative Stress; D011498:Protein Precursors / Q000096:biosynthesis*; D049231:Saposins; D015398:Signal Transduction; D014407:Tumor Cells, Cultured; D015854:Up-Regulation
D000970:Antineoplastic Agents; D002518:Ceramides; D006023:Glycoproteins; D016023:Integrins; D011498:Protein Precursors; D049231:Saposins; D017313:Fenretinide