Transient renal tubular acidosis in a neonate following transplacental acetazolamide.
Renal tubular acidosis (RTA) was observed in a preterm boy shortly after birth. His mother had glaucoma and had been treated during pregnancy with oral acetazolamide, a carbonic anhydrase inhibitor. When RTA developed, acetazolamide was detected in his serum demonstrating transplacental acetazolamide passage.
Ozawa
H
H
Azuma
E
E
Shindo
K
K
Higashigawa
M
M
Mukouhara
R
R
Komada
Y
Y
D000086:Acetazolamide / Q000009:adverse effects* / Q000378:metabolism; D000141:Acidosis, Renal Tubular / Q000139:chemically induced* / Q000175:diagnosis* / Q000378:metabolism; D002257:Carbonic Anhydrase Inhibitors / Q000009:adverse effects* / Q000378:metabolism; D004232:Diuretics / Q000009:adverse effects* / Q000378:metabolism; D005260:Female; D005901:Glaucoma / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000378:metabolism; D011254:Pregnancy in Diabetics / Q000378:metabolism; D011297:Prenatal Exposure Delayed Effects
D002257:Carbonic Anhydrase Inhibitors; D004232:Diuretics; D000086:Acetazolamide