title: Adolescent gingival squamous cell carcinoma: Report of a case and review of the literature.
abstract: In this article we describe a case of adolescent squamous cell carcinoma of the gingiva. The tumor presented as an ulcerative lesion of the gingiva that was originally thought to be pseudoepitheliomatous hyperplasia. The pathologic differentiation between squamous cell carcinoma and pseudoepitheliomatous hyperplasia is discussed and a review of the literature with respect to pediatric and adolescent oral squamous cell carcinoma is presented. The reported case illustrates the difficulties that may be encountered in attempting to histopathologically distinguish between pseudoepitheliomatous hyperplasia and well-differentiated squamous cell carcinoma of the oral cavity.
authors.affiliation: Department of Plastic Surgery, University of Virginia, Health Science Center, Charlottesville, Va, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Bill
authors.forename: V R
authors.initials: VR
authors.lastname: Reddy
authors.forename: K L
authors.initials: KL
authors.lastname: Ries
authors.forename: T J
authors.initials: TJ
authors.lastname: Gampper
authors.forename: M A
authors.initials: MA
authors.lastname: Hoard
mesh_terms: D000293:Adolescent; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003937:Diagnosis, Differential; D004848:Epithelium / Q000473:pathology; D005881:Gingiva / Q000473:pathology; D005882:Gingival Diseases / Q000473:pathology; D005887:Gingival Neoplasms / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D015603:Keratinocytes / Q000473:pathology; D008297:Male; D019226:Oral Ulcer / Q000473:pathology