Hyperdiploidy in a case of favorable histology Wilms tumor.
Hyperdiploidy is useful in defining histologic variants of Wilms tumor and prognosis in other childhood cancers. We describe a case of hyperdiploid favorable histology Wilms tumor (50,XY,+6,+7,+8,+10,+12,-21[2]/51,idem,+9[6]/46,XY[12]) in a 3-year-old boy, and review the literature for other hyperdiploid childhood renal lesions.
Sandoval
C
C
Department of Pediatrics, New York Medical College, Munger Pavilion Room 110, Valhalla, NY 10595, USA.
Ozkaynak
M F
MF
Tugal
O
O
Jayabose
S
S
D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D004171:Diploidy; D006801:Humans; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D008297:Male; D009396:Wilms Tumor / Q000235:genetics* / Q000473:pathology / Q000601:surgery