Porcine adenoviruses: an update on genome analysis and vector development.
Although porcine adenoviruses (PAdV) are present in the swine populations worldwide, they usually do not cause any disease, or the infection is only manifested in a mild diarrhoea or respiratory signs. The importance of adenoviruses, however, is constantly growing as there is a possibility of developing them into viral vector vaccines against more significant swine pathogens. A short summary of the well-established facts of porcine adenoviruses is given and recent developments of the genetic analysis of these viruses are discussed in detail. The possibilities of vector development and examples of vector vaccines already reported in the literature are mentioned.
Nagy
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Veterinary Medical Research Institute, Hungarian Academy of Sciences, H-1581 Budapest, P.O. Box 18, Hungary.
Tuboly
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D000818:Animals; D005822:Genetic Vectors; D016679:Genome, Viral; D017921:Mastadenovirus / Q000145:classification* / Q000235:genetics* / Q000276:immunology; D017422:Sequence Analysis, DNA; D012703:Serotyping; D013552:Swine; D014765:Viral Vaccines
D014765:Viral Vaccines