title: Distant metastases from sinonasal cancer.
abstract: Distant metastases from sinonasal malignancy are generally a rare event except in the terminal stages of the diseases and many patients die from recurrence before the secondaries become clinically manifest. Sinonasal neoplasia covers a diverse range of pathologies, some of which have a greater tendency to spread than others, in particular adenoid cystic carcinoma, malignant melanoma and some of the sarcomas. Notwithstanding this, the frequency with which systemic metastases occurs is such that screening at presentation could not be regarded as cost-effective and is consequently only instituted in the presence of specific symptoms.
authors.affiliation: Institute of Laryngology and Otology, Royal National Throat Nose and Ear Hospital, London, UK. v.lund@ucl.ac.uk
authors.forename: V J
authors.initials: VJ
authors.lastname: Lund
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000556:secondary; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary; D016609:Neoplasms, Second Primary / Q000175:diagnosis; D017599:Neuroectodermal Tumors / Q000556:secondary; D010255:Paranasal Sinus Neoplasms / Q000473:pathology* / Q000517:prevention & control*; D013964:Thyroid Neoplasms / Q000556:secondary