title: [A possibility to predict the severity of individual damage following the exposure to supralethal radiation dosage. Prediction of the clinical manifestation of radiation injury in laboratory animals by response to pre-exposure hypobaric hypoxia].
abstract: The experiments on rats, dogs and monkeys exposed to radiation doses which cause intestinal and cerebral forms of radiation sickness have shown that the severity of a clinical state can be predicted by cardiovascular and endocrine changes when a pre-exposure test with moderate hypobaric hypoxia is performed. The goodness of fit of experimental data to the exposed result is up to 60-80%, still rising if a set of indices of the neuroendocrine status is used.
authors.affiliation: State Research Centre of Russia-Institute of Biophysics, Moscow, 123182 Russia.
authors.forename: N G
authors.initials: NG
authors.lastname: Darenskaia
authors.forename: A O
authors.initials: AO
authors.lastname: Korotkevich
authors.forename: T A
authors.initials: TA
authors.lastname: Nasonova
authors.forename: T S
authors.initials: TS
authors.lastname: Maliutina
mesh_terms: D000818:Animals; D004285:Dogs; D000860:Hypoxia / Q000503:physiopathology*; D008252:Macaca fascicularis; D008297:Male; D011237:Predictive Value of Tests; D011379:Prognosis; D011832:Radiation Injuries / Q000503:physiopathology*; D051381:Rats; D012720:Severity of Illness Index