title: Hypocretin (orexin) input to trigeminal and hypoglossal motoneurons in the cat: a double-labeling immunohistochemical study.
abstract: In trigeminal and hypoglossal motor nuclei of adult cats, hypocretin immunoreactive fiber varicosities were observed in apposition to retrogradely labeled motoneuron somata and dendrites. Among those lateral hypothalamus neurons that project to the hypoglossal nucleus some were determined to be hypocretin immunoreactive and were located amongst the single-labeled hypocretinergic neurons. These data suggest that hypocretin may play a role in the synaptic control of these motoneurons.
authors.affiliation: Department of Physiology, UCLA School of Medicine, Los Angeles, CA 90095, USA. sjfung@ucla.edu
authors.forename: S J
authors.initials: SJ
authors.lastname: Fung
authors.forename: J
authors.initials: J
authors.lastname: Yamuy
authors.forename: S
authors.initials: S
authors.lastname: Sampogna
authors.forename: F R
authors.initials: FR
authors.lastname: Morales
authors.forename: M H
authors.initials: MH
authors.lastname: Chase
mesh_terms: D000818:Animals; D000906:Antibodies; D002352:Carrier Proteins / Q000032:analysis* / Q000276:immunology; D002415:Cats; D003429:Cross Reactions; D007002:Hypoglossal Nerve / Q000737:chemistry* / Q000166:cytology; D007026:Hypothalamic Area, Lateral / Q000737:chemistry / Q000166:cytology; D007150:Immunohistochemistry; D047908:Intracellular Signaling Peptides and Proteins; D009046:Motor Neurons / Q000737:chemistry*; D009434:Neural Pathways; D009479:Neuropeptides / Q000032:analysis* / Q000276:immunology; D000068797:Orexins; D012119:Respiration; D013569:Synapses / Q000737:chemistry; D014278:Trigeminal Nuclei / Q000737:chemistry* / Q000166:cytology
chemical_list: D000906:Antibodies; D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D000068797:Orexins