[Scanning microscopy and immunohistochemical studies of an explanted phacic posterior chamber lens (ICL-M, STAAR)].
OBJECTIVE
This study was performed to find out if an explanted phacic collamer IOL (ICL/STAAR) showed structural or surface quality changes after an intraocular implantation.


METHODS
We explanted an ICL 6 months after implantation and compared it to a new reference lens using scanning electron microscopy and immunohistochemical investigations.


RESULTS
The explanted ICL showed no changes in comparison to a new ICL except for a coating with an unidentified material. Both the new and explanted ICL presented grooves on the surface and superficial holes of unknown origin measuring roughly 10 mu. Neither pigment nor macrophages could be found on the explanted lens. Although the lens material contained 0.1% collagen, the immunohistochemical staining for collagen was negative.


CONCLUSIONS
The collagen content of the ICL could not be proven using immunohistochemistry. No changes were found between the new and the explanted lens, except for a coating of the explanted lens with an unidentified material.
Keuch
R
R
Augenabteilung der Schlosspark-Klinik Berlin, Heubnerweg 2, 14059 Berlin.
Schnoy
N
N
Bleckmann
H
H
D003094:Collagen / Q000648:ultrastructure; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009216:Myopia / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D013499:Surface Properties
D003094:Collagen