7-Hydroxyphthalide: a new natural salicylaldehyde analog from Oulenzia sp. (Astigmata: Winterschmitiidae).
A new salicyl lactone was detected from the unidentified Oulenzia sp. and its chemical structure was elucidated as 7-hydroxyphthalide (7-hydroxy-3H-isobenzofuran-1-one), based on its GC/MS and GC/FT-IR data and SiO2 column behavior. The compound was synthesized by NaBH4 reduction of 3-hydroxyphthalic anhydride. The GC/MS and GC/FT-IR spectra of the natural compound were consistent with those of the synthetic product. Although the compound is known as a medical material, this is the first example of its presence in nature.
Shimizu
N
N
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan.
Kuwahara
Y
Y
D000447:Aldehydes / Q000737:chemistry*; D000818:Animals; D001572:Benzofurans / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008925:Mites / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
C437411:7-hydroxyphthalide; D000447:Aldehydes; D001572:Benzofurans; D007202:Indicators and Reagents