Cytochalasin D from Hypocrella bambusae.
Cytochalasin D which shows marked cytotoxic effects on multi-tumor cells was newly isolated at high content(5.28 mg/g, dry weight) from Fungus Hypocrella bambusae(B.et Br.) Sacc. Its structure was elucidated by spectroscopic methods. Two-dimensional NMR techniques were applied to make complete assignment for the 1H- and 13C-NMR chemical shifts of this compound.
Xu
H
H
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.
Fang
W S
WS
Chen
X G
XG
He
W Y
WY
Cheng
K D
KD
D000818:Animals; D001203:Ascomycota / Q000737:chemistry*; D002681:China; D015638:Cytochalasin D / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D019384:Nucleic Acid Synthesis Inhibitors / Q000737:chemistry / Q000302:isolation & purification
D019384:Nucleic Acid Synthesis Inhibitors; D015638:Cytochalasin D