title: Neonatal screening of phenylketonuria and congenital hypothyroidism in China.
abstract: Mass screening of newborns for some congenital metabolic diseases is a tremendous achievement in the field of preventive medicine. The pilot study of neonatal screening in China was started in 1981. According to the results of 1.1 million newborn screenings from 8 big cities in the past 6 years, the incidence of phenylketonuria was 1/14,767 and congenital hypothyroidism was 1/5,469. China is a vast country with great economic differences among the different regions, making neonatal screening difficult in some areas. The national neonatal screening coverage rate is only about 2 % at the moment, but in metropolitan centers like Shanghai, the coverage rate reached 95 % in 1997.
authors.affiliation: Xin Hua Hospital, Shanghai Second Medical University, Shanghai Institute for Pediatric Research, China. xhkj@public.sta.net.cn
authors.forename: G X
authors.initials: GX
authors.lastname: Fan
authors.forename: Y
authors.initials: Y
authors.lastname: Jun
authors.forename: C
authors.initials: C
authors.lastname: Rui-guan
mesh_terms: D002681:China / Q000453:epidemiology; D003409:Congenital Hypothyroidism; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D015994:Incidence; D007231:Infant, Newborn; D015997:Neonatal Screening; D010661:Phenylketonurias / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy