title: [Reversed C.P.C.: Aggressive NK-cell leukemia/lymphoma].
abstract: While natural killer(NK)-cell type granular lymphocyte-proliferative disorders(GLPD) generally represent benign disorders, acute NK-cell leukemia/lymphoma is a rare but a very aggressive disorder. We report a case characterized by an extranodal(nasal) and bone marrow infiltration of large granular lymphocyte morphology, CD3-CD16-CD56+ phenotype. The patient's course became severe and refractory. Multiorgan failure, associated with intravascular coagulation syndrome was the main cause of death.
authors.affiliation: Graduate School of Allied Health Sciences, Tokyo Medical and Dental University.
authors.forename: T
authors.initials: T
authors.lastname: Koyama
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015703:Antigens, CD / Q000032:analysis; D017809:Fatal Outcome; D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology*; D007945:Leukemia, Lymphoid / Q000276:immunology / Q000473:pathology*; D008223:Lymphoma / Q000276:immunology / Q000473:pathology*; D008297:Male
chemical_list: D015703:Antigens, CD