title: [Analysis of DNA status in bone marrow cells of mice internally irradiated with 90Sr ].
abstract: The response of bone marrow cells of CBA mice injected with 22.2, 222 and 592 kBq/animal to additional gamma-irradiation (3 Gy) for testing purposes was evaluated using SCG (Comet assay). A decrease in induction of DNA damage right after additional gamma-irradiation was determined. It correlated with bone marrow cell quantity and the tail length before additional gamma-irradiation. The results support the suggestion about the activation of DNA repair in bone marrow cells under exposure to 90Sr in vivo.
authors.affiliation: Ural Research Center for Radiation Medicine, Chelyabinsk, 454076 Russia. pryakhin@urcrm.chel.su
authors.forename: E A
authors.initials: EA
authors.lastname: Priakhin
authors.forename: V S
authors.initials: VS
authors.lastname: Korytnyĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Akleev
authors.forename: L I
authors.initials: LI
authors.lastname: Krupitskaia
authors.forename: G G
authors.initials: GG
authors.lastname: Anisimova
authors.forename: E I
authors.initials: EI
authors.lastname: Tolstykh
authors.forename: G A
authors.initials: GA
authors.lastname: Triapitsyna
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000528:radiation effects*; D020552:Comet Assay; D004249:DNA Damage / Q000528:radiation effects*; D004260:DNA Repair; D005720:Gamma Rays; D051379:Mice; D008808:Mice, Inbred CBA; D013326:Strontium Radioisotopes
chemical_list: D013326:Strontium Radioisotopes