title: Identification of a MADS-box gene, FLOWERING LOCUS M, that represses flowering.
abstract: The timing of flowering is important for the reproductive success of plants. Here we describe the identification and characterization of a new MADS-box gene, FLOWERING LOCUS M (FLM), which is involved in the transition from vegetative to reproductive development. FLM is similar in amino-acid sequence to FLC, another MADS-box gene involved in flowering-time control. flm mutants are early flowering in both inductive and non-inductive photoperiods, and flowering time is sensitive to FLM dosage. FLM overexpression produces late-flowering plants. Thus FLM acts as an inhibitor of flowering. FLM is expressed in areas of cell division such as root and shoot apical regions and leaf primordia.
authors.affiliation: Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, WI 53706-1544, USA.
authors.forename: K C
authors.initials: KC
authors.lastname: Scortecci
authors.forename: S D
authors.initials: SD
authors.lastname: Michaels
authors.forename: R M
authors.initials: RM
authors.lastname: Amasino
mesh_terms: D000595:Amino Acid Sequence; D018744:DNA, Plant; D004268:DNA-Binding Proteins / Q000145:classification / Q000235:genetics*; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D026161:MADS Domain Proteins; D008969:Molecular Sequence Data; D009154:Mutation; D010641:Phenotype; D017440:Photoperiod; D063245:Plant Development; D010940:Plant Proteins; D018517:Plant Roots / Q000235:genetics; D018547:Plant Stems / Q000235:genetics; D010944:Plants / Q000235:genetics*; D030821:Plants, Genetically Modified; D012326:RNA Splicing; D018749:RNA, Plant; D012098:Reproduction / Q000235:genetics; D013997:Time Factors; D014157:Transcription Factors / Q000145:classification / Q000235:genetics*
chemical_list: D018744:DNA, Plant; D004268:DNA-Binding Proteins; D026161:MADS Domain Proteins; D010940:Plant Proteins; D018749:RNA, Plant; D014157:Transcription Factors