title: An alternative route for Carboni-Lindsey reaction: N,N cycloaddition of an alkene to s-tetrazine.
abstract: Quantum mechanical calculations show that N,N cycloaddition of alkenes and alkynes to s-tetrazines is possible as an alternative to the well-known C,C cycloaddition (Carboni-Lindsey reaction). Formation of 1,2,4-triazole derivatives (formal product of N,N cycloaddition) along with the pyrazole (formal product of C,C cycloaddition) corroborates this theoretical prediction.
authors.affiliation: The Institutes for Applied Research and the Department of Chemistry, Ben-Gurion University of the Negev, POB 653, Beer-Sheva 84105, Israel.
authors.forename: X
authors.initials: X
authors.lastname: Zhou
authors.forename: E G
authors.initials: EG
authors.lastname: Kovalev
authors.forename: J T
authors.initials: JT
authors.lastname: Klug
authors.forename: V
authors.initials: V
authors.lastname: Khodorkovsky