[Kearns-Sayre syndrome with GH deficiency].
A case of Kearns-Sayre syndrome with failure to thrive, cytochrome oxidase deficiency in muscle fibers, mtDNA deletion and deficient GH responses to stimulation tests is reported. The patient, when 9 years old, was treated with GH without significant improvement in growth velocity. The opportunity of search for GH deficiency in children with Kearns-Sayre syndrome and failure to thrive is stressed.
Berio
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Cattedra di Pediatria dell'Università di Genova, DIPE, Istituto Gaslini, Quarto, Genova, Italia.
Piazzi
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D000293:Adolescent; D002648:Child; D005260:Female; D019382:Human Growth Hormone / Q000172:deficiency*; D006801:Humans; D007625:Kearns-Sayre Syndrome / Q000150:complications*
D019382:Human Growth Hormone