title: Sex difference in alcohol-related organ injury.
abstract: This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Nobuhiro Sato and Kai O. Lindros. The presentations were (1) Sex differences in ethanol pharmacokinetics, by E. Baraona; (2) Estrogen regulates the sensitivity to endotoxin in hepatic Kupffer cells, by K. Ikejima; (3) Sex difference in alcohol-related organ injury, by E. Mezey; (4) Aggravated ethanol-induced liver injury in female rats: Protection by the antiestrogen toremifene, by Harri A. Järveläinen; and (5) Alcohol metabolism in Asian subjects: Sex differences and flushing response, by V. A. Ramchandani.
authors.affiliation: Department of Gastroenterology (NS, KI), Juntendo University School of Medicine, Tokyo, Japan. nsato@med.juntendo.ac.jp
authors.forename: N
authors.initials: N
authors.lastname: Sato
authors.forename: K O
authors.initials: KO
authors.lastname: Lindros
authors.forename: E
authors.initials: E
authors.lastname: Baraona
authors.forename: K
authors.initials: K
authors.lastname: Ikejima
authors.forename: E
authors.initials: E
authors.lastname: Mezey
authors.forename: H A
authors.initials: HA
authors.lastname: Järveläinen
authors.forename: V A
authors.initials: VA
authors.lastname: Ramchandani
mesh_terms: D000426:Alcohol Dehydrogenase / Q000378:metabolism*; D019973:Alcohol-Related Disorders / Q000208:ethnology / Q000378:metabolism*; D000818:Animals; D001925:Brain Damage, Chronic / Q000139:chemically induced / Q000378:metabolism; D002492:Central Nervous System Depressants / Q000493:pharmacokinetics*; D020847:Estrogen Receptor Modulators / Q000627:therapeutic use; D000431:Ethanol / Q000493:pharmacokinetics*; D005235:Fatty Liver, Alcoholic / Q000188:drug therapy / Q000378:metabolism; D005260:Female; D005483:Flushing / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D006331:Heart Diseases / Q000378:metabolism; D006801:Humans; D007728:Kupffer Cells / Q000187:drug effects / Q000378:metabolism; D008297:Male; D020845:Selective Estrogen Receptor Modulators / Q000627:therapeutic use; D012737:Sex Factors; D017312:Toremifene / Q000627:therapeutic use
chemical_list: D002492:Central Nervous System Depressants; D020847:Estrogen Receptor Modulators; D012739:Gonadal Steroid Hormones; D020845:Selective Estrogen Receptor Modulators; D000431:Ethanol; D017312:Toremifene; D000426:Alcohol Dehydrogenase