Role of plasma ANG II in the excretion of acute sodium load in a bird with salt glands (Anas platyrhynchos).
This study was designed to further examine the role of plasma ANG II in the excretion of sodium in the Pekin duck, a bird with salt glands. Renal and extrarenal (salt gland) excretion of an intravenously administered isotonic saline load was monitored over a 4-h period in a group of eight birds under two conditions: the control condition, in which isotonic saline infusion decreased endogenous plasma ANG II from 102.6 to 16.5 pg/ml, and the experimental condition, in which ANG II suppression was prevented by intravenous infusion of a 3.5 ng. kg(-1). min(-1) dose of synthetic ANG II. ANG II infusion significantly decreased the total sodium excretion (by 15%), primarily via an inhibition of salt gland output. The results suggest that ANG II suppression facilitates the excretion of an administered sodium load in birds with salt glands.
Heinz
M K
MK
Department of Physiology, University of the Witwatersrand, Johannesburg 2050, South Africa. myriamh@twrinet.twr.ac.za
Gray
D A
DA
D000804:Angiotensin II / Q000097:blood* / Q000494:pharmacology; D000818:Animals; D004372:Ducks; D005260:Female; D007668:Kidney / Q000502:physiology*; D008297:Male; D009318:Natriuresis / Q000187:drug effects / Q000502:physiology; D009994:Osmolar Concentration; D012491:Salt Gland / Q000502:physiology*; D012964:Sodium / Q000097:blood* / Q000652:urine*; D014556:Urine; D014662:Vasoconstrictor Agents / Q000097:blood* / Q000494:pharmacology
D014662:Vasoconstrictor Agents; D000804:Angiotensin II; D012964:Sodium