Chiral helicity induced by hydrogen bonding and chirality of podand histidyl moieties.
[structure: see text] The single-crystal X-ray structure determination of N,N'-bis[(S)-(+)-1-methoxycarbonyl-2-(4-imidazolyl)ethyl]-2,6-pyridinedicarboxamide (L-BHisPA) and the D-isomer (D-BHisPA) derived from the corresponding chiral histidine revealed a left- and right-handed helical conformation, respectively, through intramolecular hydrogen bonding and chirality of the podand histidyl moieties. Furthermore, each helical molecule is connected by continuous intermolecular hydrogen bonds to afford a left- or right-handed helical assembly, respectively, in the crystal packing.
Moriuchi
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Department of Applied Chemistry, Faculty of Engineering,Osaka University, Yamada-oka, Suita, Osaka 565-0871, Japan.
Nishiyama
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M
Yoshida
K
K
Ishikawa
T
T
Hirao
T
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