Prevalence of anti-hepatitis E virus antibodies in different Indian animal species.
Prevalence of IgG antibodies to hepatitis E virus (IgG-anti-HEV) was determined among different animal species from India. Seropositivity varied from 4.4% to 6.9% in cattle, 54.6-74.4% in pigs and 2.1-21.5% in rodents. Of the 44 dogs screened, 10 were positive (22.7%). None of the 250 goat sera tested were found to be anti-HEV positive. Among rodents, over 50% serum samples collected in 1985 from Bandicota bengalensis were positive for anti-HEV antibodies. No evidence of HEV infection was obtained following experimental inoculation of an Indian strain (AKL-90) of HEV into anti-HEV negative pigs and goats. The results document varied prevalence of anti-HEV antibodies in different animal species from India and of inability of Indian pigs and goats to support replication of at least one human strain of HEV.
Arankalle
V A
VA
Hepatitis Division, National Institute of Virology, 20-A, Dr Ambedkar Road, Pune 411001, India. aarankalle@hotmail.com
Joshi
M V
MV
Kulkarni
A M
AM
Gandhe
S S
SS
Chobe
L P
LP
Rautmare
S S
SS
Mishra
A C
AC
Padbidri
V S
VS
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002417:Cattle; D004285:Dogs; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005243:Feces / Q000821:virology; D006041:Goats; D016751:Hepatitis E / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D016752:Hepatitis E virus / Q000276:immunology*; D006524:Hepatitis, Viral, Animal / Q000453:epidemiology* / Q000276:immunology; D007074:Immunoglobulin G / Q000097:blood; D007194:India / Q000453:epidemiology; D008297:Male; D012367:RNA, Viral / Q000737:chemistry / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D012377:Rodentia; D016036:Seroepidemiologic Studies; D013552:Swine
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D012367:RNA, Viral