Membranoproliferative glomerulonephritis associated with hypocomplementemic urticarial vasculitis after complete remission of membranous nephropathy.
A 49-year-old-man developed proteinuria in 1978. He was diagnosed as having membranous nephropathy by renal biopsy and was treated with prednisolone. The proteinuria disappeared completely and the treatment was stopped. In 1995, after complete remission, he developed nephrotic syndrome with chronic urticaria and hypocomplementemia. Renal biopsy revealed membranoproliferative glomerulonephritis (type I) and skin biopsy showed leukocytoclastic vasculitis, which was compatible with hypocomplementemic vasculitis syndrome. Steroid therapy was very effective.
Saeki
T
T
Department of Internal Medicine, Nagaoka Red Cross Hospital, Nagaoka, Japan. saekit@nagoka.jrc.or.jp
Ueno
M
M
Shimada
H
H
Nishi
S
S
Imai
N
N
Miyamura
S
S
Gejou
F
F
Arakawa
M
M
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003165:Complement System Proteins / Q000172:deficiency*; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D015433:Glomerulonephritis, Membranous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D014581:Urticaria / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D014657:Vasculitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D000893:Anti-Inflammatory Agents; D003165:Complement System Proteins; D011239:Prednisolone