Whole-genome analysis: annotations and updates.
The most important advances in the field of genome annotation over the past two years involve the use of cDNA sequences, protein structures and gene expression data to predict genes. These types of information not only improve gene identification, but they also give insights into variation in gene structure and function.
Gaasterland
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Laboratory of Computational Genomics, 1230 York Avenue, Rockefeller University, New York, New York 10021, USA. gaasterl@genomes.rockefeller.edu
Oprea
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D017398:Alternative Splicing; D000818:Animals; D018076:DNA, Complementary; D004926:Escherichia coli / Q000235:genetics; D020224:Expressed Sequence Tags; D015870:Gene Expression; D016678:Genome; D015894:Genome, Human; D023281:Genomics / Q000379:methods*; D006801:Humans; D051379:Mice / Q000235:genetics; D009876:Operon; D011506:Proteins / Q000235:genetics / Q000378:metabolism
D018076:DNA, Complementary; D011506:Proteins