title: [Laboratory diagnosis of the status of the hemostasis system].
abstract: Activators of fibrinogen, prothrombin and protein C isolated from venoms of Agkistrodon halys halys and Echis multisquamatus may be used as a tool both for thrombosis investigations in the model systems and for diagnostic in the clinical practice. The complex of diagnostic tests developed on the base of these activators allows to characterize the haemostatic system at different pathologies and as well as to determine the unbalance between separate components of haemostasis. The tests are approved on plasma of patients with heart diseases, ulcers, nephrites, hestoses etc. The tests are sensitive, informative, easy to use and do not require an additional equipment. They have no analogues in Ukraine.
authors.affiliation: Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv.
authors.forename: T M
authors.initials: TM
authors.lastname: Platonova
authors.forename: T M
authors.initials: TM
authors.lastname: Chernyshenko
authors.forename: O V
authors.initials: OV
authors.lastname: Hornyts'ka
authors.forename: O M
authors.initials: OM
authors.lastname: Savchuk
authors.forename: L I
authors.initials: LI
authors.lastname: Sokolovs'ka
authors.forename: M Sh
authors.initials: MSh
authors.lastname: Hamisoniia
authors.forename: Ie M
authors.initials: IeM
authors.lastname: Makohonenko
mesh_terms: D001778:Blood Coagulation Disorders / Q000097:blood / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D006487:Hemostasis; D012680:Sensitivity and Specificity; D014757:Viper Venoms / Q000737:chemistry
chemical_list: D014757:Viper Venoms