Control of an outbreak of infection due to extended-spectrum beta-lactamase--producing Escherichia coli in a liver transplantation unit.
We report an outbreak of infection due to genotypically identical extended-spectrum beta-lactamase--producing Escherichia coli among patients in a liver transplantation unit. Control of the outbreak was achieved by a combination of contact isolation, feedback on hand hygiene, and gut decontamination with an orally administered fluoroquinolone. These interventions led to abrupt curtailment of the outbreak.
Paterson
D L
DL
Infectious Disease Section, Veterans Affairs Medical Center, Pittsburgh, PA, USA.
Singh
N
N
Rihs
J D
JD
Squier
C
C
Rihs
B L
BL
Muder
R R
RR
D004196:Disease Outbreaks; D004926:Escherichia coli / Q000201:enzymology*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D006757:Hospital Units; D006801:Humans; D017053:Infection Control / Q000379:methods*; D016031:Liver Transplantation; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases