Excitatory synaptic transmission in neonatal dorsal horn: NMDA and ATP receptors.
Postnatal development sees a strong synaptogenesis in rat superficial dorsal horn. My studies show that synapses mediated by two excitatory neurotransmitters, glutamate and ATP, are functional since the very first postnatal days. Using an electrophysiological approach, the functional properties of two receptors activated by these neurotransmitters, glutamatergic NMDA and ATP ionotropic receptors, are described.
Bardoni
R
R
Dipartimento di Scienze Biomediche-Sezione di Fisiologia, Università di Modena e Reggio Emilia, 41100 Modena, Italy.
D000818:Animals; D000831:Animals, Newborn; D020671:Posterior Horn Cells / Q000254:growth & development / Q000502:physiology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology*; D018048:Receptors, Purinergic P2 / Q000502:physiology*; D013569:Synapses / Q000502:physiology*
D016194:Receptors, N-Methyl-D-Aspartate; D018048:Receptors, Purinergic P2