title: [Pathogenesis of chronic hepatitis B].
abstract: The following problems are considered in chronic HBV infection: viral replication within and outside the liver, heterogenicity of genotypes and mutations of viral genome, immunogenetic basis of the host, direct cytopathic effect of the virus and immunological reactions induced by the virus.
authors.affiliation: I. M. Sechenov Moscow Medical Academy, 119881, Moscow.
authors.forename: Z G
authors.initials: ZG
authors.lastname: Aprosina
authors.forename: V V
authors.initials: VV
authors.lastname: Serov
mesh_terms: D000818:Animals; D019694:Hepatitis B, Chronic / Q000209:etiology*; D006801:Humans; D051379:Mice