Proteinase-Activated Receptors: New Functions for Old Enzymes.
Although proteases are traditionally viewed as degradative enzymes, characterization of a family of G protein-coupled receptors that are activated by proteolysis reveals a new role. Certain proteases function as signaling molecules that specifically regulate cells by cleaving and activating a family of proteinase-activated receptors.
Böhm
Stephan K.
SK
Dept. of Surgery, University of California San Francisco, San Francisco, CA 94143-0660, USA.
McConalogue
Karen
K
Kong
Wuyi
W
Bunnett
Nigel W.
NW