Alcohol withdrawal kindling: mechanisms and implications for treatment.
This article represents the proceedings of a workshop at the 2000 ISBRA Meeting in Yokohama, Japan. The chair was Larry P. Gonzalez. The presentations were (1) EEG indices of sensitization in a murine model of repeated ethanol withdrawals, by Lynn M. Veatch; (2) Long-term changes in central nervous system function after repeated alcohol withdrawals: Recommendations for the treatment of acute withdrawal, by Larry P. Gonzalez; (3) Differential regulation of GABAA and NMDA receptors by repeated ethanol treatment in cultured mammalian neurons, by Maharaj K. Ticku; and (4) Involvement of GABAA and NMDA receptors in alcohol withdrawal kindling: Implications for treatment, by Howard C. Becker.
Gonzalez
L P
LP
Department of Psychiatry & Behavioral Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190-3000, USA. Larry-Gonzalez@ouhsc.edu
Veatch
L M
LM
Ticku
M K
MK
Becker
H C
HC
D000818:Animals; D002478:Cells, Cultured; D002492:Central Nervous System Depressants / Q000009:adverse effects / Q000494:pharmacology*; D004569:Electroencephalography / Q000187:drug effects*; D000431:Ethanol / Q000009:adverse effects / Q000494:pharmacology*; D006801:Humans; D007696:Kindling, Neurologic / Q000187:drug effects* / Q000502:physiology; D051379:Mice; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D011963:Receptors, GABA-A / Q000187:drug effects* / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects* / Q000502:physiology; D013375:Substance Withdrawal Syndrome / Q000628:therapy
D002492:Central Nervous System Depressants; D011963:Receptors, GABA-A; D016194:Receptors, N-Methyl-D-Aspartate; D000431:Ethanol