[Anti-Coxsakie B viruses humoral immunity status in patients with pancreatic diseases].
Similar titers and incidence of antibodies to group-specific Coxsackie B virus antigen were detected in 137 patients with chronic pancreatitis and 127 patients with insulin-dependent diabetes mellitus (IDDM). Characteristic clinical features of chronic pancreatitis associated with the presence of antibodies to Coxsackie B virus in high titers were detected. HLA Cw2 antigen is significantly more incident in the phenotype of patients with chronic pancreatitis and IDDM and high titers of antibodies to Coxsackie B virus. These data confirm the possible contribution of Coxsackie B virus infection to the development of IDDM and suggest its contribution to development of chronic pancreatitis.
Trukhan
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D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology; D000917:Antibody Formation; D002908:Chronic Disease; D003384:Coxsackievirus Infections / Q000097:blood / Q000150:complications / Q000276:immunology*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000209:etiology / Q000276:immunology* / Q000821:virology; D004770:Enterovirus / Q000276:immunology*; D006801:Humans; D010195:Pancreatitis / Q000097:blood / Q000209:etiology / Q000276:immunology* / Q000821:virology
D000914:Antibodies, Viral