Eosinophilic infiltrates in a pulmonary allograft: a case and review of the literature.
An unusual case of peribronchial eosinophilic infiltrates associated with peripheral blood eosinophilia in a lung transplant patient is described. The role that eosinophils play in lung allograft rejection is reviewed. Tissue eosinophils have been associated with acute pulmonary allograft rejection. Although, eosinophils in bronchoalveolar lavage fluid (BAL) have been observed in allograft rejection, this relationship is less well defined. The role of eosinophils in the pathophysiology of allograft rejection is unclear.
Mogayzel
P J
PJ
Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA. mogayzel@mail.jhmi.edu
Yang
S C
SC
Wise
B V
BV
Colombani
P M
PM
D002102:Cadaver; D002648:Child; D003550:Cystic Fibrosis / Q000601:surgery; D004802:Eosinophilia / Q000097:blood* / Q000473:pathology; D004804:Eosinophils / Q000378:metabolism*; D005260:Female; D006084:Graft Rejection / Q000097:blood* / Q000473:pathology; D006801:Humans; D016040:Lung Transplantation / Q000473:pathology*