Alcoholic liver disease and apoptosis.
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Carol A. Casey and Amin Nanji. The presentations were (1) Mechanisms of apoptosis in alcoholic liver disease, by Amin A. Nanji; (2) Impaired receptor-mediated endocytosis: Its role in alcoholic apoptosis, by Carol A. Casey; (3) Toxicity of ethanol in HepG2 cells that express CYP2E1, by Arthur I. Cederbaum; (4) Mitochondrial regulation of ethanol-induced hepatocyte apoptosis, by M. Adachi; and (5) Apoptosis in alcoholic hepatitis, by T. Takahashi.
Casey
C A
CA
Departments of Internal Medicine and Biochemistry and Molecular Biology, University of Nebraska Medical Center, and VA Medical Center, Omaha, Nebraska 68105, USA. ccasey@unmc.edu
Nanji
A
A
Cederbaum
A I
AI
Adachi
M
M
Takahashi
T
T
D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D037263:Asialoglycoprotein Receptor; D016923:Cell Death / Q000187:drug effects / Q000502:physiology; D002492:Central Nervous System Depressants / Q000494:pharmacology; D019392:Cytochrome P-450 CYP2E1 / Q000187:drug effects / Q000378:metabolism*; D004705:Endocytosis / Q000187:drug effects / Q000502:physiology*; D000431:Ethanol / Q000494:pharmacology; D006519:Hepatitis, Alcoholic / Q000378:metabolism; D022781:Hepatocytes / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000378:metabolism / Q000503:physiopathology*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000378:metabolism
D037263:Asialoglycoprotein Receptor; D002492:Central Nervous System Depressants; D011956:Receptors, Cell Surface; D000431:Ethanol; D019392:Cytochrome P-450 CYP2E1