title: Catalytic Asymmetric Vinylogous Mukaiyama-aldol (CAVM) reactions: the enolate activation.
abstract: The Catalytic Asymmetric Vinylogous Mukaiyama (CAVM) reactions of various aldehydes with dienolate 1 using different enolate activations (CuF*(S)-TolBinap, t-BuOCu*(S)-Tol-Binap, and various chiral nonracemic ammonium fluorides derived from cinchona alkaloids) are described. These reactions proved to be highly regioselective leading exclusively to the alpha-aldol products in good yields and poor to good enantioselectivities.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS, F-91198 Gif-sur-Yvette, France.
authors.forename: G
authors.initials: G
authors.lastname: Bluet
authors.forename: J M
authors.initials: JM
authors.lastname: Campagne