[Effect of shenfukang on nephropathy rats induced by adriamycin].
Adriamycin-induced nephropathy (AIN) model in rats (mainlining 7.5 mg/kg avoirdupois adiramycine) was adopted to explore the effect of Shenfukang (SFK). The results showed that SFK could remarkably reduce the content of urine protein, cholesterol, creatinine and urinary nitrogen in serum, MDA in serum and renal cortex of AIN model rats. And SFK also could increase the content of album and golbulin in serum, the activities of SOD in serum and renal cortex of AIN model rats.


CONCLUSIONS
SFK played an important role on AIN.
Zhou
J
J
Dept. of Pharmacology, Guangzhou University of TCM, Guangzhou 510405.
Liao
X
X
Li
R
R
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000633:toxicity; D004317:Doxorubicin / Q000633:toxicity; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D008297:Male; D009401:Nephrosis / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D029757:Tripterygium
D000903:Antibiotics, Antineoplastic; D004365:Drugs, Chinese Herbal; D004317:Doxorubicin