Chemoselective cross-metathesis reaction. Application to the synthesis of the C1-C14 fragment of amphidinol 3.
[reaction: see text] An efficient synthesis of the C1-C14 fragment of amphidinol 3 is described. The synthesis is based on chemoselective cross-metathesis reactions and enantioselective allyltitanations.
BouzBouz
S
S
Laboratoire de Chimie Organique associé au CNRS, ESPCI, 10 rue Vauquelin, 75231 - Paris Cedex 05, France.
Cossy
J
J
D000475:Alkenes / Q000138:chemical synthesis*; D000818:Animals; D000935:Antifungal Agents / Q000138:chemical synthesis*; D004141:Dinoflagellida / Q000737:chemistry*; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis*; D013237:Stereoisomerism; D000095722:Amphidinols
D000475:Alkenes; D000935:Antifungal Agents; D011714:Pyrans; C438973:amphidinol 3; D000095722:Amphidinols