title: Clarithromycin resistance and eradication of Helicobacter pylori in children.
abstract: Outcome of Helicobacter pylori infection was analyzed in 61 children treated with a triple therapy including clarithromycin. Bacterial eradication was obtained in all children with clarithromycin-susceptible strains but not in children with clarithromycin-resistant ones (P = 0.0001). H. pylori antimicrobial susceptibility is mandatory before choosing a treatment, and clarithromycin should be avoided in case of resistance.
authors.affiliation: Division of Gastroenterology, Department of Pediatrics, Hôpital Saint Vincent de Paul, 75674 Paris Cedex 14, France.
authors.forename: N
authors.initials: N
authors.lastname: Kalach
authors.forename: P H
authors.initials: PH
authors.lastname: Benhamou
authors.forename: F
authors.initials: F
authors.lastname: Campeotto
authors.forename: M
authors.initials: M
authors.lastname: Bergeret
authors.forename: C
authors.initials: C
authors.lastname: Dupont
authors.forename: J
authors.initials: J
authors.lastname: Raymond
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D017291:Clarithromycin / Q000494:pharmacology* / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008297:Male
chemical_list: D017291:Clarithromycin