title: Hepatic cirrhosis in a five-month-old dog.
abstract: The clinicopathological features of an unusual case of a five-month-old male Spanish mastiff, which was presented with clinical signs indicative of severe hepatic failure, are reported. Fluid replacement therapy, colloid plasma expanders, antibiotics and diuretic drugs were unsuccessful in improving the animal's general condition, and euthanasia was elected by the owner. On necropsy, ascites and severe cirrhosis, with extensive periacinar necrosis, was found. Cirrhosis is a rare lesion in young dogs. The most common causes are circulatory disturbances, hereditary metabolic disorders or poisoning, such as aflatoxicosis and anticonvulsant therapy. The possible involvement of canine adenovirus in this case is discussed.
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, University of Córdoba, Hospital Clínico Veterinario, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Lucena
authors.forename: E
authors.initials: E
authors.lastname: Mozos
authors.forename: M J
authors.initials: MJ
authors.lastname: Bautista
authors.forename: P J
authors.initials: PJ
authors.lastname: Ginel
authors.forename: J
authors.initials: J
authors.lastname: Pérez
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001947:Breeding; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male