Highly selective one-pot synthesis of spirophosphoranes exhibiting reversed apicophilicity by oxidation of dianions generated from P-H spirophosphorane.
[see reaction]. Mild and highly selective one-pot procedures for obtaining phosphoranes that exhibit reversed (O-cis) apicophilicity are described. On the basis of the procedures, O-cis phosphorane bearing an aryl group (R = 2,4,6-tri-i-propylphenyl) could be isolated for the first time; the procedure is also applicable for alkyl derivatives. Particularly effective was the use of I2 as an oxidizing reagent.
Kajiyama
K
K
Department of Chemistry, Graduate School of Science, Hiroshima University, 1-3-1Kagamiyama, Higashi-Hiroshima 739-8526, Japan.
Yoshimune
M
M
Nakamoto
M
M
Matsukawa
S
S
Kojima
S
S
Akiba
K
K