title: [Cerebellar pilocytic astrocytomas in children. Report of 72 cases].
abstract: OBJECTIVE
  Cerebellar pilocytic astrocytoma (CPA) bears a well-deserved reputation of benignity. However, these tumors infiltrate the brainstem in a number of cases, and total removal may cause morbidity, whereas subtotal removal can lead to recurrence.
  
  
  METHODS
  To define guidelines for tumor removal, management of tumor remnants and recurrence, we reviewed 72 cases of CPA of childhood operated on in our department since the introduction of CT.
  
  
  RESULTS
  Surgical removal was total in 57 cases, had to be withheld because of brainstem infiltration in nine cases, and was revealed subtotal by postoperative imaging in six cases. Two of the latter were reoperated on; six had only radiological controls and did not progress. Early in the series, eight children had external irradiation because of subtotal removal or recurrence. Three children were reoperated on for tumor recurrence, between six and eight years after complete removal. We had no tumor-related mortality; long-term disability could be related to previous mental retardation, the severity of clinical state at presentation, and complications of surgery and irradiation.
  
  
  CONCLUSIONS
  The goal of surgery is to cure the patient with minimal morbidity, however, total removal is not always possible. In our experience: i) tumor remnants can be surveyed radiologically, and reoperated only in case of progression; ii) the indications for radiotherapy should be the exception; iii) clinical and radiological follow-up should be protracted beyond entry into adulthood.
authors.affiliation: Service de Neurochirurgie Pédiatrique, Hôpital Roger-Salengro, CHRU, 59037 Lille Cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Vinchon
authors.forename: R
authors.initials: R
authors.lastname: Assaker
authors.forename: G
authors.initials: G
authors.lastname: Soto-Ares
authors.forename: M M
authors.initials: MM
authors.lastname: Ruchoux
authors.forename: P
authors.initials: P
authors.lastname: Dhellemmes
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000175:diagnosis / Q000601:surgery*; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology