Plasma Proteins Case Report: Massive Bone Marrow Necrosis with Polyclonal Hypergammaglobulinemia and Blue Toe Syndrome.
Massive bone marrow necrosis was rare, and most of these cases were accompanied with malignant disease. We report a case that was thought to be idiopathic massive bone marrow necrosis. It was a 58 y.o. male who was admitted because of blue toe syndrome and hypergammaglobulinemia. We tried to detect malignant diseases with computed tomography and gallium scintigraphy, and infectious diseases with bacterial culture and viral antibodies, but all of them were negative. Pancytopenia and bone marrow necrosis was not improved, and he had died after 5-month hospitalization. Autopsy revealed massive bone marrow necrosis and bone marrow fibrosis after necrosis, but malignant or infectious diseases were not detected. It may be diagnosed as idiopathic massive bone marrow necrosis.
Murayama
TOHRU
T
Third Division, Department of Medicine, and.
Hayashi
YOSHITAKE
Y
Imoto
SHION
S
Shimoyama
MANABU
M
Matsuoka
HIROSHI
H
Nagata
AKI
A
Iwata
NOBUKO
N
Taniguchi
TAIZO
T
Ito
MITSUHIRO
M
Ito
HIROSHI
H
Chihara
KAZUO
K
Matsui
TOSHIMITSU
T