title: Dithiane- and trithiane-based photolabile scaffolds for molecular recognition.
abstract: [see structure]. A modular synthetic approach to novel dithiane- and trithiane-based photolabile molecular hosts equipped with elements of molecular recognition is developed. The approach provides ready access to a family of amino-derivatized photocleavable molecular systems capable of hydrogen-bonding-based recognition of biologically relevant molecules, e.g., ureas, barbiturates etc. These systems undergo efficient photofragmentation in the presence of external (e.g., benzophenone) or internal (e.g., nitropyridine) electron-transfer sensitizers.
authors.affiliation: Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado 80208-2436, USA.
authors.forename: O D
authors.initials: OD
authors.lastname: Mitkin
authors.forename: A N
authors.initials: AN
authors.lastname: Kurchan
authors.forename: Y
authors.initials: Y
authors.lastname: Wan
authors.forename: B F
authors.initials: BF
authors.lastname: Schiwal
authors.forename: A G
authors.initials: AG
authors.lastname: Kutateladze
mesh_terms: D006571:Heterocyclic Compounds / Q000737:chemistry*; D010777:Photochemistry
chemical_list: D006571:Heterocyclic Compounds