title: Early improvement during manual-guided cognitive and dynamic psychotherapies predicts 16-week remission status.
abstract: This study examined the extent to which improvement from baseline to weeks 2, 3, and 4 on the Beck Depression Inventory and Beck Anxiety Inventory predict week 16 clinical remission for patients with major depressive disorder, generalized anxiety disorder, and/or obsessive-compulsive or avoidant personality disorders who were receiving manual-based psychotherapies. Logistic regression and receiver-operator characteristic analyses revealed relatively accurate identification of remitters and nonremitters based on improvement from baseline to sessions 2 to 4 in both original and cross-validation samples. Predictive success did not vary as a function of diagnosis, treatment type (cognitive or dynamic), or treatment status (short-term or long-term). The clinical implications of the results are discussed.
authors.affiliation: Department of Psychiatry, University of Pennsylvania, 3535 Market Street, Philadelphia, PA 19104, USA.
authors.forename: P
authors.initials: P
authors.lastname: Crits-Christoph
authors.forename: M B
authors.initials: MB
authors.lastname: Connolly
authors.forename: R
authors.initials: R
authors.lastname: Gallop
authors.forename: J P
authors.initials: JP
authors.lastname: Barber
authors.forename: X
authors.initials: X
authors.lastname: Tu
authors.forename: M
authors.initials: M
authors.lastname: Gladis
authors.forename: L
authors.initials: L
authors.lastname: Siqueland
mesh_terms: D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000523:psychology / Q000628:therapy*; D015928:Cognitive Behavioral Therapy; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000523:psychology / Q000628:therapy*; D011237:Predictive Value of Tests; D011379:Prognosis; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D016896:Treatment Outcome