title: Technetium-99m tetrofosmin scintigraphy for detecting malignant lymphoma.
abstract: The aim of this study was to assess the use of Tc-99m tetrofosmin (Tc-TF) scintigraphy for detecting malignant lymphomas. In the study, before any chemotherapy, 50 patients with malignant lymphoma underwent Tc-TF scintigraphy, which was performed 10 minutes after intravenous injection of 20 mCt Tc-TF. Tc-TF scintigraphy detected malignant lymphoma in 44 (88%) patients. However, there were no significant differences in the incidences of positive and negative Tc-TF scintigraphic results between female versus male patients, HD versus NHL patients, stage I-II versus stage III-IV patients, age > 40 years versus < or = 40 years patients and patients with B symptoms false-negative results occurred in 4 (8%) infradiaphragmatic malignant lymphoma. We conclude patients with that Tc-TF scintigraphy appears suitable for detecting malignant lymphoma, especially supradiaphragmatic lesions.
authors.affiliation: Department of Nuclear Medicine, China Medical College Hospital, Taichung, Taiwan.
authors.forename: J K
authors.initials: JK
authors.lastname: Lee
authors.forename: S C
authors.initials: SC
authors.lastname: Tsai
authors.forename: Y J
authors.initials: YJ
authors.lastname: Ho
authors.forename: S P
authors.initials: SP
authors.lastname: Changlai
authors.forename: C H
authors.initials: CH
authors.lastname: Kao
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin