[Involvement of the nucleus accumbens in immune response stimulation following activation of opioid mu-receptors by DAGO].
The data obtained suggest that the agonist of the nucleus accumbens' mu-opioid receptor DAGO significantly increases the number of plaque- and rosette-forming cells following immunisation with sheep red blood cells in sham-operated Wistar rats. Bilateral destruction of the n. accumbens inhibited the immune response.
Devoĭno
L V
LV
State Research Institute of Physiology, Russian Acad. Sci., Siberian Branch, Russia, 630090, Novosibirsk, Pr. Lavrentyeva, 10.
Cheĭdo
M A
MA
Al'perina
E L
EL
D000818:Animals; D000921:Antibody-Producing Cells; D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)- / Q000494:pharmacology*; D006462:Hemolytic Plaque Technique; D007075:Immunoglobulin M / Q000378:metabolism; D008297:Male; D015213:Neuroimmunomodulation / Q000502:physiology*; D009714:Nucleus Accumbens / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D017450:Receptors, Opioid, mu / Q000819:agonists / Q000502:physiology*; D012397:Rosette Formation
D007075:Immunoglobulin M; D017450:Receptors, Opioid, mu; D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)-