title: Acute paraplegia in a patient with spinal tophi: a case report.
abstract: A 28-year-old man with a 5-year history of gouty arthritis suffered from an acute episode of lower back pain. He visited a rehabilitative clinic and received physical therapy following his examination. Weakness and numbness of both lower legs developed rapidly after physical therapy. He was sent to our hospital with complete paralysis of both lower limbs and complete sensory loss below the umbilicus 3 hours after the physical therapy. No peripheral tophi were found. Myelography showed an extrinsic compression of the dura sac at T10. Emergency decompressive laminectomy of T9 to T11 was performed. During the surgery, caseous material was found deposited in the ligamentum flavum and the left T9 to T10 facet joint, with indentation of the dura sac. The pathologic diagnosis was spinal tophi. After surgery, the patient's neurologic function recovered rapidly. It was suspected that inappropriate physical therapy might have aggravated acute inflammation of spinal gout and resulted in a rapid deterioration of neurologic function. Though gout is a chronic medical disease, an acute attack of spinal gout may be disastrous and requires emergency neurosurgical intervention.
authors.affiliation: Neurosurgical Service, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, 138 Shen-Li Road, Tainan, Taiwan.
authors.forename: L C
authors.initials: LC
authors.lastname: Wang
authors.forename: Y C
authors.initials: YC
authors.lastname: Hung
authors.forename: E J
authors.initials: EJ
authors.lastname: Lee
authors.forename: H H
authors.initials: HH
authors.lastname: Chen
mesh_terms: D000208:Acute Disease; D000328:Adult; D015210:Arthritis, Gouty / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010264:Paraplegia / Q000209:etiology*; D013122:Spinal Diseases / Q000150:complications*; D014057:Tomography, X-Ray Computed