title: [Effect of vitamin E and its functional analogs with different molecular structures on growth and lipids content of Pythium debaryanum].
abstract: The effect of exogenously added vitamin E and its synthetic analogues (the hydrophilic form of vitamin E and chromans C13 and C1) on the growth, lipogenic activity, and the fatty acid composition of the eicosapolyenoic acid-synthesizing oomycete Pythium debaryanum was studied. The effect was found to depend on the molecular structure of particular compounds. For instance, vitamin E and chroman C13 stimulated fungal growth, whereas chroman C1 inhibited it. The hydrophilic form of vitamin E enhanced the lipogenic activity of the oomycete. The studied compounds, which possess antioxidant activity, did not exert any noticeable effect on the level and the degree of the unsaturation of fungal lipids.
authors.affiliation: Moscow State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 117571 Russia.
authors.forename: Ia E
authors.initials: IaE
authors.lastname: Sergeeva
authors.forename: L A
authors.initials: LA
authors.lastname: Galanina
authors.forename: E P
authors.initials: EP
authors.lastname: Tkachevskaia
authors.forename: I V
authors.initials: IV
authors.lastname: Konova
authors.forename: R P
authors.initials: RP
authors.lastname: Evstigneeva
mesh_terms: D050356:Lipid Metabolism; D011775:Pythium / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D013329:Structure-Activity Relationship; D014810:Vitamin E / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D014810:Vitamin E