Uncoupling Proteins: Do They Have a Role in Body Weight Regulation?
Several members of the mitochondrial carrier protein family are classified as uncoupling proteins. In contrast to the uncoupling protein specific to brown adipose tissue (UCP1), the physiological role of skeletal muscle uncoupling proteins (UCP2 and UCP3) in weight regulation seems more closely associated with the regulation of lipids as fuel substrate than as mediators of adaptive thermogenesis.
Dulloo
Abdul.G.
AG
Institute of Physiology, University of Fribourg, CH-1700 Fribourg, Switzerland.
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