title: Use of a transurethral microwave thermotherapeutic device with permanent pacemakers and implantable defibrillators.
abstract: OBJECTIVE
  To determine whether a device (Urologix Targis system) used for transurethral microwave treatment interferes with sensing, pacing, and arrhythmia detection by permanent pacemakers and implantable cardioverter-defibrillators (ICDs).
  
  
  METHODS
  We tested 13 pacemakers in both bipolar and unipolar sensing configurations and 8 ICDs in vitro. Pacemakers and ICDs were programmed to their most sensitive settings. Energy outputs of the microwave device were typical of those used clinically. The probe of the microwave device was anchored 1.2 cm from the pacemaker or ICD being tested.
  
  
  RESULTS
  No sensing, pacing, or arrhythmic interactions were noted with any ICD or any pacemaker programmed to the bipolar configuration. One pacemaker (Guidant Vigor 1230) showed intermittent tracking when programmed to the unipolar configuration.
  
  
  CONCLUSIONS
  Most patients with permanent pacemakers or ICDs can safely undergo transurethral microwave therapy using the device tested. Pacemakers and ICDs should be programmed to the bipolar configuration (if available) during therapy. The pacemaker or ICD should be interrogated before and after therapy to determine whether programming changes occurred as a result of treatment. However, our findings suggest that this is unlikely.
authors.affiliation: Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Rasmussen
authors.forename: R F
authors.initials: RF
authors.lastname: Rea
authors.forename: J L
authors.initials: JL
authors.lastname: Tri
authors.forename: T R
authors.initials: TR
authors.lastname: Larson
authors.forename: D L
authors.initials: DL
authors.lastname: Hayes
mesh_terms: D016477:Artifacts; D017147:Defibrillators, Implantable / Q000145:classification / Q000600:supply & distribution; D004562:Electrocardiography; D004867:Equipment Design; D004869:Equipment Safety; D006801:Humans; D008422:Materials Testing; D008872:Microwaves / Q000009:adverse effects / Q000627:therapeutic use*; D008991:Monitoring, Physiologic; D010138:Pacemaker, Artificial / Q000145:classification / Q000600:supply & distribution; D012780:Short-Wave Therapy / Q000009:adverse effects / Q000295:instrumentation*