title: [Disseminated strongyloidiasis].
abstract: ENDEMIC ZONES: Strongyloidiasis is an intestinal parasitosis which is frequently found in tropical and subtropical regions. RISK: The "autoinfection" cycle during this helminthiasis explains why the infection can be perpetuated without further exposure to exogenous, infective larvae. Hyperinfection may occur by dissemination of Strongyloides stercoralis in immuno-compromised patients, particularly those under corticotherapy. DISSEMINATATED STRONGYLOIDIASIS: Disseminated strongyloidiasis is characterized by severe gastrointestinal and respiratory tract involvement, meningitis, skin rash, or Gram-negative bacteremia. Since disseminated stronglyoidiasis is fatal in 80% of cases it is imperative to diagnose and treat this condition before long-term corticotherapy. Ivermectin is currently recommended because it is effective and well tolerated.
authors.affiliation: Service de Parasitologie et Mycologie, CHU Pitié Salpêtrière, Paris.
authors.forename: J P
authors.initials: JP
authors.lastname: Nozais
authors.forename: M
authors.initials: M
authors.lastname: Thellier
authors.forename: A
authors.initials: A
authors.lastname: Datry
authors.forename: M
authors.initials: M
authors.lastname: Danis
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000328:Adult; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000969:Antinematodal Agents / Q000627:therapeutic use; D002648:Child; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007231:Infant, Newborn; D007559:Ivermectin / Q000627:therapeutic use; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D017171:Strongyloides stercoralis / Q000502:physiology; D013322:Strongyloidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D013827:Thiabendazole / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000871:Anthelmintics; D000969:Antinematodal Agents; D007166:Immunosuppressive Agents; D007559:Ivermectin; D015766:Albendazole; D013827:Thiabendazole