title: Surgical treatment of intracranial cavernous angiomas.
abstract: We present a surgical series of 35 patients (25 males and 10 females) with histopathologically verified intracranial cavernous angiomas. The 35 malformations were located as follows: 21 were in the cerebral hemispheres; 4 in the lateral ventricles, 4 in the brain stem; and 6 in the cerebellum. Seizures and focal neurological deficits were the main clinical features observed in patients with intracranial cavernous angiomas. A number of these vascular malformations were misdiagnosed by computerized tomography. In the last 10 years, magnetic resonance imaging has been the most sensitive method for detecting these lesions. Thirty-five cavernous angiomas were treated surgically; in 33 patients a complete excision, and in 2 patients subtotal excision were obtained. One of the patients died one year after the operation. The overall outcome was good in all of the 34 remaining patients, resulting in improved seizure control or neurological deficit. The rationale for neurologic differential diagnosis and surgical treatment and follow up results are discussed.
authors.affiliation: School of Medicine, Department of Neurosurgery, Ankara University, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Attar
authors.forename: H C
authors.initials: HC
authors.lastname: Ugur
authors.forename: A
authors.initials: A
authors.lastname: Savas
authors.forename: N
authors.initials: N
authors.lastname: Yüceer
authors.forename: N
authors.initials: N
authors.lastname: Egemen
mesh_terms: D000293:Adolescent; D000328:Adult; D015901:Angiography, Digital Subtraction; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery*; D001933:Brain Stem / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology*; D002648:Child; D004827:Epilepsy / Q000209:etiology; D005260:Female; D006392:Hemangioma, Cavernous / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D020547:Lateral Ventricles / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome