title: Catalytic asymmetric vinylation of ketone enolates.
abstract: [see reaction]. A protocol for the catalytic asymmetric vinylation of ketone enolates has been developed. Key to the success of this process was the development of new electron-rich chiral monodentate ligands.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors.forename: A
authors.initials: A
authors.lastname: Chieffi
authors.forename: K
authors.initials: K
authors.lastname: Kamikawa
authors.forename: J
authors.initials: J
authors.lastname: Ahman
authors.forename: J M
authors.initials: JM
authors.lastname: Fox
authors.forename: S L
authors.initials: SL
authors.lastname: Buchwald
mesh_terms: D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D007659:Ketones; D014753:Vinyl Compounds