Fluoride concentrations of unstimulated whole and labial gland saliva in young adults after fluoride intake with milk.
Following a fluoride depletion period 6 subjects repeatedly rinsed with 30-ml volumes of milk with or without added fluoride (5 ppm). Rinsing time was timed according to the measurements on how long it took to drink 200 or 500 ml milk. Rinsing with fluoridated milk for a total interval of 20 and 60 s, respectively, did not influence significantly the fluoride concentration of unstimulated centrifuged whole saliva 45 min later. Neither the urinary fluoride concentration nor the fluoride excretion were significantly affected by rinsing with fluoridated milk during the first hour. However, intake of 1 or 2.5 mg of fluoride with 200 and 500 ml milk, respectively, resulted in significant elevations in whole saliva fluoride levels 45 min later. In addition, the fluoride excretions into urine produced during 60 min after the fluoride intakes were significantly elevated and those reflected the ingested dose of fluoride. The intake of either 1 or 2.5mg fluoride with milk did not significantly influence the fluoride level of unstimulated labial gland saliva collected simultaneously with whole saliva.
Boros
I
I
Department of Oral Biology, Faculty of Dentistry, Semmelweis University, Budapest, Hungary. borild@net.sote.hu
Keszler
P
P
Bánóczy
J
J
D000328:Adult; D000818:Animals; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000032:analysis* / Q000493:pharmacokinetics; D005260:Female; D005459:Fluorides / Q000008:administration & dosage* / Q000032:analysis* / Q000493:pharmacokinetics / Q000652:urine; D006801:Humans; D016014:Linear Models; D008046:Lip; D008297:Male; D008892:Milk / Q000737:chemistry*; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012470:Salivary Glands, Minor / Q000378:metabolism; D012636:Secretory Rate; D014556:Urine
D002327:Cariostatic Agents; D005459:Fluorides