title: A simple preparation of ketones. N-protected alpha-amino ketones from alpha-amino acids.
abstract: [reaction: see text] Carboxylic acids and amino acids are readily converted, under mild conditions, into the corresponding activated esters, which are reacted with Grignard/CuI reagent to give the corresponding ketones in nearly quantitative yields. The compounds were recovered substantially pure from the reaction mixtures.
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Sassari, Via Vienna 2, I-07100 Sassari, Italy.
authors.forename: L
authors.initials: L
authors.lastname: De Luca
authors.forename: G
authors.initials: G
authors.lastname: Giacomelli
authors.forename: A
authors.initials: A
authors.lastname: Porcheddu