title: Living dangerously: how Helicobacter pylori survives in the human stomach.
abstract: Helicobacter pylori was already present in the stomach of primitive humans as they left Africa and spread through the world. Today, it still chronically infects more than 50% of the human population, causing, in some cases, severe diseases such as peptic ulcers and stomach cancer. To succeed in these long-term associations, H. pylori has developed a unique set of virulence factors, which allow survival in a unique and hostile ecological niche--the human stomach.
authors.affiliation: Centro CNR Biomembrane e Dipartimento di Scienze Biomediche, Università di Padova, Via G. Colombo 3, 35121 Padova, Italy. cesare@civ.bio.unipd.it
authors.forename: C
authors.initials: C
authors.lastname: Montecucco
authors.forename: R
authors.initials: R
authors.lastname: Rappuoli
mesh_terms: D016481:Helicobacter Infections / Q000382:microbiology* / Q000503:physiopathology*; D016480:Helicobacter pylori / Q000502:physiology*; D006801:Humans; D013270:Stomach / Q000382:microbiology / Q000503:physiopathology; D013272:Stomach Diseases / Q000209:etiology / Q000382:microbiology* / Q000503:physiopathology