title: Transient fetal hypothyroidism due to direct fetal administration of amiodarone for drug resistant fetal tachycardia.
abstract: Amiodarone, an anti-arrhythmic drug that contains 39% iodine, is rarely known to cause negative effects on fetal thyroid function after gestational exposure, when given orally to a pregnant woman. Two cases of fetal hypothyroidism after gestational exposure to amiodarone by direct fetal intravenous route are described here.
authors.affiliation: Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Brussels-Jette, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Vanbesien
authors.forename: A
authors.initials: A
authors.lastname: Casteels
authors.forename: A
authors.initials: A
authors.lastname: Bougatef
authors.forename: L
authors.initials: L
authors.lastname: De Catte
authors.forename: W
authors.initials: W
authors.lastname: Foulon
authors.forename: S
authors.initials: S
authors.lastname: De Bock
authors.forename: J
authors.initials: J
authors.lastname: Smitz
authors.forename: J
authors.initials: J
authors.lastname: De Schepper
mesh_terms: D000328:Adult; D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced* / Q000188:drug therapy*; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced* / Q000188:drug therapy; D007231:Infant, Newborn; D007275:Injections, Intravenous; D008297:Male; D011247:Pregnancy; D013617:Tachycardia, Supraventricular / Q000188:drug therapy*; D013974:Thyroxine / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone; D013974:Thyroxine