title: Chromoblastomycosis: clinical and mycologic experience of 51 cases.
abstract: This is a study of 51 cases of chromoblastomycosis detected in a 17-year period, all of which were clinically and mycologically proven by direct examinations, cultures and biopsies. The therapeutic results of the various treatments used are reported. Most cases were males (36 of 51; 70%), the mean age was 35 years and farmers predominated (74%); the most frequent lesions were in the lower limbs (54%). Major clinical presentations were nodular (41%) and verrucous (26%). The principal aetiologic agent isolated was Fonsecaea pedrosoi (90%). Overall results of the various treatments were as follows: 31% were cured, 57% improved and 12% failed. The best results were obtained with cryosurgery for small lesions, with itraconazole for large ones, and in some cases the combination of both treatments.
authors.affiliation: Dermatology Service and Mycology Department, General Hospital of Mexico, Mexico City, Mexico. bonyalx@servidor.unam.mx
authors.forename: A
authors.initials: A
authors.lastname: Bonifaz
authors.forename: E
authors.initials: E
authors.lastname: Carrasco-Gerard
authors.forename: A
authors.initials: A
authors.lastname: Saúl
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D002648:Child; D002862:Chromoblastomycosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology; D003452:Cryosurgery; D003881:Dermatomycoses / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology; D005260:Female; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D008297:Male; D010676:Phialophora / Q000302:isolation & purification; D012189:Retrospective Studies
chemical_list: D000935:Antifungal Agents