title: Fluid Shear Stress Modulation of Gene Expression in Endothelial Cells.
abstract: The vascular endothelium, lining the blood vessel wall, is constantly exposed to wall shear stresses generated by flowing blood. Gene regulation, critical for endothelial cell function, depends on complex interactions at the promoter level and utilizes overlapping signal transduction cascades to activate the expression of genes involved in many biological processes.
authors.affiliation: Vascular Diseases Research Unit, Glaxo-Wellcome Medicines Research Centre, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK.
authors.forename: Martin
authors.initials: M
authors.lastname: Braddock
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Schwachtgen
authors.forename: Parul
authors.initials: P
authors.lastname: Houston
authors.forename: Marion C.
authors.initials: MC
authors.lastname: Dickson
authors.forename: Michael J.
authors.initials: MJ
authors.lastname: Lee
authors.forename: Callum J.
authors.initials: CJ
authors.lastname: Campbell