title: The pattern electroretinogram (PERG) with contralateral corneal reference.
abstract: The pattern electroretinogram (PERG) is a sensitive test for investigation of the proximal retina. For monocular recording, the contralateral corneal reference (CCR) electrode position has been suggested as a possible alternative to the conventional ipsilateral temporal reference (ITR). We therefore compared the effect of these electrode positions on 26 subjects (median age 45.5 years, IQR 24.5-61.5). The signals were recorded monocularly with DTL nylon fibre electrodes. The visual stimuli were high contrast 19' black-white checkerboard patterns, reversing 4 times/s. PERG responses obtained from the CCR gave larger amplitudes and the increase in amplitude was statistically significant (P < 0.001). Because the CCR signal is larger, new normative ranges must be established to avoid false negative results.
authors.affiliation: Department of Optometry and Vision Sciences, Cardiff University, P.O. Box 905, King Edward VII Avenue, Cardiff, Wales CF10 3YJ, UK.
authors.forename: Y H
authors.initials: YH
authors.lastname: Aldebasi
authors.forename: N
authors.initials: N
authors.lastname: Drasdo
authors.forename: R V
authors.initials: RV
authors.lastname: North
authors.forename: J E
authors.initials: JE
authors.lastname: Morgan
mesh_terms: D000328:Adult; D000368:Aged; D004596:Electroretinography / Q000295:instrumentation / Q000379:methods / Q000592:standards; D006801:Humans; D008875:Middle Aged; D012016:Reference Values; D012160:Retina / Q000502:physiology*; D012680:Sensitivity and Specificity