[The effect of hormonal replacement therapy on symptoms of climacteric syndrome and selected metabolic parameters].
OBJECTIVE
The goal of this paper was estimation of influence of HRT (after 3 and 6 months of treatment of 112 women) the symptoms of climacteric syndrome and depression associated with the said syndrome based on the scales of Kupperman, Green, Hamilton and Beck as well as some selected parameters of metabolic state--concentration of foloculotropic hormonal profile FSH and 17 beta-estradiol E2, lipid profile (TC, HDL, LDL, TG-A) and glucose concentration.


CONCLUSIONS
1. The implementation of hormonal replacement therapy on 112 women made it possible to conclude that the treatment caused withdrawal of symptoms of climacteric syndrome and depression associated with the said syndrome. 2. Hormonal Replacement Therapy to a great extent had a beneficial influence on the lipid profile with 112 women after menopause especially as far as LDL is concerned. 3. HRT caused enormously significant increase in 17 beta-estradiol concentration and decrease of FSH concentration. 4. HRT statistically had no impact on glucose level with the study group of women.
Kornaga
E
E
Katedry i Kliniki Endokrynologii Ginekologicznej AM w Poznaniu.
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D002979:Climacteric / Q000187:drug effects* / Q000378:metabolism*; D004958:Estradiol / Q000032:analysis; D005260:Female; D005640:Follicle Stimulating Hormone / Q000032:analysis; D020249:Hormone Replacement Therapy; D006801:Humans; D007044:Hysterectomy; D050356:Lipid Metabolism; D008077:Lipoproteins, LDL / Q000032:analysis; D008875:Middle Aged
D001786:Blood Glucose; D008077:Lipoproteins, LDL; D004958:Estradiol; D005640:Follicle Stimulating Hormone