Two new germacranolides from Magnolia grandiflora.
Two new sesquiterpenoids, 4,5-epoxy-13-methoxy-1(10)-germacren-12,6-olide and 4,5-epoxy-13-acetoxy-1(10)-germacren-12,6-olide, were isolated from the leaves of Magnolia grandiflora, together with six known compounds, 2alpha-hydroxy-dihydroparthenolide, parthenolide, costunolide, syringaresinol, (+) medioresinol and 6,7-dimethoxycoumarin. The structures of the new compounds were elucidated on the basis of spectroscopic methods and X-ray diffraction.
Wu
S H
SH
Kunming Institute of Botany, Chinese Academy of Sciences, Yuman.
Luo
X D
XD
Ma
Y B
YB
Hao
X J
XJ
Zhou
J
J
Wu
D G
DG
D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D029562:Magnoliaceae / Q000737:chemistry*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045788:Sesquiterpenes, Germacrane; D014961:X-Ray Diffraction
C439533:4,5-epoxy-13-acetoxy-1(10)-germacren-12,6-olide; C439532:4,5-epoxy-13-methoxy-1(10)-germacren-12,6-olide; D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; D045788:Sesquiterpenes, Germacrane