Ethanol and lipid metabolic signaling.
This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Shivendra D. Shukla and Grace Y. Sun. The presentations were (1) Metabolic turnover of ethanol into cellular lipids and platelet activating factor, by Shivendra D. Shukla; (2) Ethanol action on the phospholipase A2 signaling pathways in astrocytes, by Grace Y. Sun; (3) Mechanisms of ethanol-induced perturbation of lipoprotein cholesterol transport, by W. Gibson Wood; (4) Transfer of an abnormal ethanol-induced phospholipid, phosphatidylethanol, between lipoproteins, by Markku J. Savolainen; (5) Phospholipase-d-mediated formation of phosphatidylethanol, by Christer Alling; and (6) Changes in phosphoinositide signaling after chronic ethanol treatment, by Jan B. Hoek.
Shukla
S D
SD
Department of Pharmacology, University of Missouri Columbia, School of Medicine, Columbia, Missouri 65212, USA. shuklasd@missouri.edu
Sun
G Y
GY
Gibson Wood
W
W
Savolainen
M J
MJ
Alling
C
C
Hoek
J B
JB
D000818:Animals; D002492:Central Nervous System Depressants / Q000378:metabolism / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism; D000431:Ethanol / Q000378:metabolism / Q000494:pharmacology*; D020404:Glycerophospholipids / Q000378:metabolism*; D006801:Humans; D008074:Lipoproteins / Q000187:drug effects* / Q000378:metabolism; D010739:Phospholipase D / Q000187:drug effects / Q000378:metabolism; D010740:Phospholipases / Q000187:drug effects* / Q000378:metabolism; D010741:Phospholipases A / Q000187:drug effects / Q000378:metabolism; D054467:Phospholipases A2; D015398:Signal Transduction / Q000187:drug effects* / Q000502:physiology; D010738:Type C Phospholipases / Q000187:drug effects / Q000378:metabolism
D002492:Central Nervous System Depressants; D020404:Glycerophospholipids; D008074:Lipoproteins; C030104:lipoprotein cholesterol; C051521:phosphatidylethanol; D000431:Ethanol; D002784:Cholesterol; D010740:Phospholipases; D010741:Phospholipases A; D054467:Phospholipases A2; D010738:Type C Phospholipases; D010739:Phospholipase D