title: Phospholipase C Isoforms, Cytoskeletal Organization, and Vascular Smooth Muscle Differentiation.
abstract: The function of differentiated vascular smooth muscle cells (VSMC) in vivo is the regulation of contractility. Following injury or disease, however, VSMC lose their contractile function and take on a synthetic, proliferative phenotype. This dedifferentiation is generally accompanied by a change in the expression profile of phospholipase C isoforms.
authors.affiliation: Department of Clinical Pharmacology, National Heart and Lung Institute, Imperial College School of Medicine, QEQM Wing, St. Mary's Hospital, Paddington, London W2 1NY, England.
authors.forename: Joanne S.
authors.initials: JS
authors.lastname: Lymn
authors.forename: Alun D.
authors.initials: AD
authors.lastname: Hughes