A novel HLA-A*02 allele, A*02202, identified by nucleotide sequencing.
In this paper we report the identification of a new HLA-A*02 allele in two members of an Afghan family. This novel allele, designed as A*02202, differs from A*02201 by a silent substitution at codon 66 (AAC-->AAT) in the alpha1 domain. A*02202 appears to be the result of a novel mutation (Note).
Nesci
S
S
Divisione di Ematologia e Centro Trapianti Midollo Osseo di Muraglia, Azienda Ospedale "San Salvatore", Pesaro, Italy. sonianesci@libero.it
Iliescu
A
A
Buffi
O
O
Andreani
M
M
Lucarelli
G
G
D000483:Alleles; D001483:Base Sequence; D005260:Female; D005819:Genetic Markers / Q000276:immunology; D015789:HLA-A2 Antigen / Q000235:genetics* / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013789:Thalassemia / Q000235:genetics
D005819:Genetic Markers; D015789:HLA-A2 Antigen