title: Chromosomal translocation 3;22 in an infertile man.
abstract: OBJECTIVE
  To present the first case of an infertile male with a normal phenotype and chromosomal translocation 3;22.
  
  
  METHODS
  Case report.
  
  
  METHODS
  POVISA Medical Center.
  
  
  METHODS
  A 45-year-old man with primary infertility for 13 years and with different partners; the patient has a family history of recurrent miscarriages and low fertility.
  
  
  METHODS
  Lymphocytic karyotype and electron microscopy.
  
  
  METHODS
  Physical examination and semen analysis.
  
  
  RESULTS
  The semen analysis revealed oligoasthenoteratospermia. The lymphocytic karyotype detected a translocation 3;22, and electron microscopy showed a lack of the central microtubule pair and peripheral doublet.
  
  
  CONCLUSIONS
  An association between translocation 3;22 and other abnormalities in infertile males has been reported, but no such association has ever been described in men whose only clinical manifestation is infertility.
authors.affiliation: Department of Urology, POVISA Medical Center, Vigo, Spain. jlrq@yahoo.com
authors.forename: J L
authors.initials: JL
authors.lastname: Quintana de la Rosa
authors.forename: G
authors.initials: G
authors.lastname: Gallegos Avila
authors.forename: R
authors.initials: R
authors.lastname: García Cavazos
authors.forename: E
authors.initials: E
authors.lastname: Zungri Telo
mesh_terms: D002875:Chromosomes / Q000235:genetics*; D002892:Chromosomes, Human, Pair 22 / Q000235:genetics*; D002893:Chromosomes, Human, Pair 3 / Q000235:genetics*; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D007621:Karyotyping; D007962:Leukocytes / Q000502:physiology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009845:Oligospermia / Q000235:genetics; D013094:Spermatozoa / Q000648:ultrastructure; D014178:Translocation, Genetic / Q000235:genetics*