title: New ligands bearing chiral bioactive fragments.
abstract: [see reaction]. Reliable and practical synthetic routes for the construction of hybrid molecules bearing both a chelating center and a useful biofunction are presented. They comprise the sequential cross-coupling reaction between ethynylated synthons with iodo-substituted L-tyrosine derivatives and provide access to various rationally designed chiral ligands.
authors.affiliation: Laboratoire de Chimie, d'Electronique et de Photonique Moléculaires, Associé au CNRS ESA-7008, Ecole de Chimie, Polymères, Matériaux de Strasbourg, 25 rue Becquerel, 67087 Strasbourg Cedex 02, France.
authors.forename: A
authors.initials: A
authors.lastname: Khatyr
authors.forename: R
authors.initials: R
authors.lastname: Ziessel
mesh_terms: D008024:Ligands; D010165:Palladium / Q000737:chemistry; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry*; D013237:Stereoisomerism; D014443:Tyrosine / Q000737:chemistry*
chemical_list: D008024:Ligands; D045322:Photosynthetic Reaction Center Complex Proteins; D014443:Tyrosine; D010165:Palladium