title: A comparison between topical and infiltrative bupivacaine and intravenous meperidine for postoperative analgesia after inguinal herniorrhaphy.
abstract: The purpose of the present study is to compare postoperative analgesia offered by the simple instillation of local anesthetic on the surgical wound, its infiltration with the same local anesthetic, and the use of an intravenous opioid. Sixty patients were divided into the three analgesia groups to be studied: instillation of local anesthetic (Group I), injection of local anesthetic (Group II), and intravenous opioid (Group III). The pain was quantified using the visual analogue scale. It was observed that there was better analgesia in Groups I and II during the first 6 hours postoperatively as compared with Group III (P < 0.0001). At the end of the 12 hours the three modes of analgesia proved comparable. However, after 24 hours there was better analgesic development in Group I, whereas Group II had greater postoperative morbidity. We conclude that the instillation of local anesthesia provides analgesia during the immediate postoperative period comparable to local infiltration using the same anesthetic. Both regional analgesia methods are more effective analgesics during the first 6 hours than are intravenous opioids. Furthermore the simple instillation of local anesthetic allows better analgesic evolution of the surgical wound after the first 24 hours considering the lower rate of resulting complications.
authors.affiliation: Department of General Surgery of Complexo Hospitalar Santa Casa de Porto Alegre, RS, Brazil.
authors.forename: F L
authors.initials: FL
authors.lastname: Waechter
authors.forename: J A
authors.initials: JA
authors.lastname: Sampaio
authors.forename: R D
authors.initials: RD
authors.lastname: Pinto
authors.forename: M R
authors.initials: MR
authors.lastname: Alvares-Da-Silva
authors.forename: L
authors.initials: L
authors.lastname: Pereira-Lima
mesh_terms: D000287:Administration, Topical; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D007275:Injections, Intravenous; D007322:Instillation, Drug; D008297:Male; D008614:Meperidine / Q000008:administration & dosage*; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D008614:Meperidine; D002045:Bupivacaine