title: The cytoplasmic truncated receptor tyrosine kinase ALK homodimer immortalizes and cooperates with ras in cellular transformation.
authors.affiliation: Institute of Clinical Pathology, Institute of Cancer Research, University of Vienna, A-1090 Vienna, Austria.
authors.forename: I
authors.initials: I
authors.lastname: Simonitsch
authors.forename: D
authors.initials: D
authors.lastname: Polgar
authors.forename: M
authors.initials: M
authors.lastname: Hajek
authors.forename: P
authors.initials: P
authors.lastname: Duchek
authors.forename: B
authors.initials: B
authors.lastname: Skrzypek
authors.forename: S
authors.initials: S
authors.lastname: Fassl
authors.forename: A
authors.initials: A
authors.lastname: Lamprecht
authors.forename: G
authors.initials: G
authors.lastname: Schmidt
authors.forename: G
authors.initials: G
authors.lastname: Krupitza
authors.forename: C
authors.initials: C
authors.lastname: Cerni
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D000818:Animals; D002455:Cell Division; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D011905:Genes, ras; D017728:Lymphoma, Large-Cell, Anaplastic / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics* / Q000378:metabolism; D000090243:Nucleophosmin; D010446:Peptide Fragments; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D051381:Rats; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics* / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D009687:Nuclear Proteins; D010446:Peptide Fragments; D011993:Recombinant Fusion Proteins; D012097:Repressor Proteins; C034811:tetracycline resistance-encoding transposon repressor protein; D000090243:Nucleophosmin; C000626175:Alk protein, rat; D000077548:Anaplastic Lymphoma Kinase; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases