[Evaluation of thyroid structure and function in patients with Turner syndromes].
The aim of our study was an estimation of thyroid structure and function in 37 patients with Turner syndrome aged from 19 to 60 years and in control group of healthy women. In each case the following studies were performed: cytogenetic examination, thyroid ultrasonography, serum total and free thyroid hormones, TSH, thyroglobulin (Tg), thyroid hormones binding globulin (TBG), antithyroglobulin and antithyroperoxidase antibodies (anti-Tg and anti-TPO) levels. In Turner syndrome ultrasonographic volume of the thyroid was significantly lower than in control group (11.03 vs 16.98 cm3). Abnormalities of thyroid function were found in 8 (22%) studied cases (subclinical primary hypothyroidism in 16%, full-clinical primary hypothyroidism in 3% and hyperthyroidism in course of Graves disease in 3%). Serum elevated antithyroid antibodies were present in 62% cases of Turner syndrome and were significantly higher than in control group (16%). In Turner syndrome thyroid diseases are more frequent than in healthy population. Every patient with Turner syndrome needs routine diagnostics of the thyroid structure and function.
Łacka
K
K
Klinika Endokrynologii IChW AM im. K. Marcinkowskiego w Poznaniu.
Wawrzyniak
M
M
Andrzejewska
J
J
Krysińska
I
I
Ruchała
M
M
Bauman-Antczak
A
A
D000328:Adult; D018450:Disease Progression; D005260:Female; D006111:Graves Disease / Q000150:complications; D006801:Humans; D008875:Middle Aged; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000000981:diagnostic imaging*; D014424:Turner Syndrome / Q000150:complications / Q000175:diagnosis*; D014463:Ultrasonography