The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting.
Maeda
H
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Department of Microbiology, Kumamoto University School of Medicine, 860-0811, Kumamoto, Japan. msmaedah@gpo.kumamoto-u.ac.jp
D000818:Animals; D019540:Area Under Curve; D001794:Blood Pressure; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000473:pathology; D016503:Drug Delivery Systems; D006801:Humans; D008099:Liver / Q000378:metabolism; D008113:Liver Neoplasms / Q000098:blood supply / Q000473:pathology; D008954:Models, Biological; D009369:Neoplasms / Q000098:blood supply* / Q000628:therapy*; D010539:Permeability; D011108:Polymers / Q000627:therapeutic use; D013997:Time Factors; D014018:Tissue Distribution; D014680:Veins / Q000378:metabolism
D011108:Polymers