title: Rescue treatment with abciximab in acute ischemic stroke.
abstract: In acute ischemic stroke, reocclusion after an initially successful thrombolysis treatment can occur and is associated with increased morbidity and mortality. The authors present the successful use of abciximab, a platelet glycoprotein IIb/IIIa receptor inhibitor, in a patient with a thrombotic occlusion of the proximal middle cerebral artery, which was refractory to combined IV and intra-arterial thrombolysis and percutaneous intracranial balloon angioplasty.
authors.affiliation: Departmens of Neurology, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: K Y
authors.initials: KY
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Heo
authors.forename: S I
authors.initials: SI
authors.lastname: Lee
authors.forename: P H
authors.initials: PH
authors.lastname: Yoon
mesh_terms: D000077284:Abciximab; D000208:Acute Disease; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D000925:Anticoagulants / Q000008:administration & dosage*; D002545:Brain Ischemia / Q000175:diagnosis / Q000628:therapy*; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000008:administration & dosage*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020521:Stroke / Q000175:diagnosis / Q000628:therapy*; D015912:Thrombolytic Therapy
chemical_list: D000911:Antibodies, Monoclonal; D000925:Anticoagulants; D007140:Immunoglobulin Fab Fragments; D000077284:Abciximab