title: Thrombolysis of extracranial and intracranial arteries after IV abciximab.
abstract: Abciximab was administered intravenously to three patients to treat thrombus associated with atherosclerotic stenosis of a supra-aortic artery. In two cases, the thrombi had been identified on a previous angiography more than a week before treatment. Successful thrombolysis was achieved with abciximab in all three cases. In this small series, abciximab had a thrombolytic effect on established thrombi that were refractory to previous antithrombotic treatment attempts.
authors.affiliation: Department of Neuroradiology and Therapeutic Angiography, Hôpital Lariboisière, Paris, France. ehoudart@compuserve.com
authors.forename: E
authors.initials: E
authors.lastname: Houdart
authors.forename: F
authors.initials: F
authors.lastname: Woimant
authors.forename: R
authors.initials: R
authors.lastname: Chapot
authors.forename: C
authors.initials: C
authors.lastname: Mounayer
authors.forename: C
authors.initials: C
authors.lastname: Soria
authors.forename: J J
authors.initials: JJ
authors.lastname: Merland
mesh_terms: D000077284:Abciximab; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D000925:Anticoagulants / Q000008:administration & dosage*; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000008:administration & dosage*; D007275:Injections, Intravenous; D002537:Intracranial Arteriosclerosis / Q000175:diagnosis / Q000628:therapy; D020767:Intracranial Thrombosis / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy
chemical_list: D000911:Antibodies, Monoclonal; D000925:Anticoagulants; D007140:Immunoglobulin Fab Fragments; D000077284:Abciximab