NMR methodology for the study of nucleic acids.
During the past few years, NMR methodology for the study of nucleic acids has benefited from new developments that greatly improved state-of-the-art technology for the precise determination of three-dimensional structures. Substantial progress has been made in designing experimental protocols for the measurement of residual dipolar couplings, in sensitivity optimization of triple-resonance experiments and in detection of hydrogen bonds and in developing computational methods for structure refinement using NMR restraints.
Zídek
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National Centre for Biomolecular Research, Masaryk University, Kotlárská 2, 611 37, Brno, Czech Republic.
Stefl
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R
Sklenár
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V
D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009696:Nucleic Acids / Q000737:chemistry; D012313:RNA / Q000737:chemistry* / Q000378:metabolism; D012680:Sensitivity and Specificity; D012997:Solvents
D009696:Nucleic Acids; D012997:Solvents; D012313:RNA; D004247:DNA