title: Amination of grignard reagents with retention of configuration.
abstract: [see reaction]. The stereochemistry of electrophilic amination has been probed using the chiral Grignard reagent 5, in which the magnesium-bearing carbon atom is the sole stereogenic center. Amination with azidomethyl phenyl sulfide 1 and with O-sulfonyloxime 2 were found to proceed with full retention of configuration.
authors.affiliation: Fachbereich Chemie der Philipps-Universität Marburg, D-35032 Marburg, Germany. rwho@chemie.uni-marburg.de
authors.forename: R W
authors.initials: RW
authors.lastname: Hoffmann
authors.forename: B
authors.initials: B
authors.lastname: Hölzer
authors.forename: O
authors.initials: O
authors.lastname: Knopff