title: Individual differences in smoking reward from de-nicotinized cigarettes.
abstract: Most studies of cigarette smoking and smoking cessation have focused on the psychopharmacological effects of nicotine; relatively few have explored the role of sensory aspects of cigarette smoke. Sensory aspects of cigarette smoke play a role in the maintenance of smoking behavior, and may be particularly important for certain smokers. This paper presents the results of a pooled analysis of nine studies conducted in our laboratory, in order to explore the influence of demographic and smoking-related variables on ratings of de-nicotinized as compared to nicotine-containing cigarettes. A major finding of this analysis is that ratings of smoking derived from de-nicotinized, but not nicotine-containing, cigarettes appear to vary with level of tobacco dependence, suggesting that sensory factors may be more important to highly dependent, as compared to less-dependent, smokers. The implications of these findings for smoking cessation treatment and for future research are discussed.
authors.affiliation: Department of Psychiatry, Duke University Medical Center, USA. braue010@umn.edu
authors.forename: L H
authors.initials: LH
authors.lastname: Brauer
authors.forename: F M
authors.initials: FM
authors.lastname: Behm
authors.forename: J D
authors.initials: JD
authors.lastname: Lane
authors.forename: E C
authors.initials: EC
authors.lastname: Westman
authors.forename: C
authors.initials: C
authors.lastname: Perkins
authors.forename: J E
authors.initials: JE
authors.lastname: Rose
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006293:Health Promotion; D006801:Humans; D008297:Male; D012201:Reward; D016540:Smoking Cessation / Q000706:statistics & numerical data*; D000074606:Smoking Prevention; D014029:Tobacco Use Disorder / Q000517:prevention & control*