title: Wernicke's encephalopathy in patients with hyperemesis gravidarum.
abstract: Our two patients presented with Wernicke's Encephalopathy (WE) resulting from prolonged hyperemesis gravidarum. This is an unusual cause of WE, a potentially fatal medical emergency due to thiamine deficiency. We discuss the clinical settings, presentation, diagnosis, neurophysiological and radiological findings, treatment and outcome of WE in these two cases and the neuropathologic correlation of this condition. We stress upon the importance of early diagnosis and prompt treatment of WE.
authors.affiliation: Department of Medicine, National University Hospital, Singapore. junetan99@yahoo.com
authors.forename: J H
authors.initials: JH
authors.lastname: Tan
authors.forename: K H
authors.initials: KH
authors.lastname: Ho
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000150:complications* / Q000188:drug therapy; D011247:Pregnancy; D013831:Thiamine / Q000627:therapeutic use; D014899:Wernicke Encephalopathy / Q000188:drug therapy / Q000209:etiology*
chemical_list: D013831:Thiamine