Coexistence of common variable immunodeficiency and autoimmune polyglandular syndrome type 2.
A six year-old boy with common variable immunodeficiency developed insulin dependent diabetes mellitus, autoimmune thyroiditis, and total alopecia leading to the diagnosis of autoimmune polyglandular syndrome type 2. Previously unreported co-occurence of these two entities may be explained by strong autoimmunity and HLA association of both conditions.
Topaloglu
A K
AK
Department of Pediatric Endocrinology and Metabolism, Faculty of Medicine, Cukurova University, Adana, Turkey.
Yuksel
B
B
Yilmaz
M
M
Mungan
N O
NO
Guneser
S
S
Ozer
G
G
D000505:Alopecia / Q000150:complications; D002675:Child, Preschool; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007158:Immunologic Techniques; D008297:Male; D016884:Polyendocrinopathies, Autoimmune / Q000145:classification* / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013967:Thyroiditis, Autoimmune / Q000150:complications
D016756:Immunoglobulins, Intravenous