title: [FISH, cytogenetic analysis].
abstract: We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our clinical experience. Furthermore, we introduced our methods of performing FISH using blood smear or G banding specimens.
authors.affiliation: Tenri Institute of Medical Research.
authors.forename: S
authors.initials: S
authors.lastname: Miyanishi
authors.forename: A
authors.initials: A
authors.lastname: Okumura
mesh_terms: D016026:Bone Marrow Transplantation; D005189:False Positive Reactions; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods; D016898:Interferon-alpha / Q000627:therapeutic use; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D018183:Transplantation Chimera
chemical_list: D016898:Interferon-alpha