title: Clinical protocol. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade Biologic) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors.
authors.forename: A
authors.initials: A
authors.lastname: Sharma
authors.forename: S
authors.initials: S
authors.lastname: Mani
authors.forename: N
authors.initials: N
authors.lastname: Hanna
authors.forename: C
authors.initials: C
authors.lastname: Guha
authors.forename: B
authors.initials: B
authors.lastname: Vikram
authors.forename: R R
authors.initials: RR
authors.lastname: Weichselbaum
authors.forename: J
authors.initials: J
authors.lastname: Sparano
authors.forename: B
authors.initials: B
authors.lastname: Sood
authors.forename: D
authors.initials: D
authors.lastname: Lee
authors.forename: W
authors.initials: W
authors.lastname: Regine
authors.forename: M
authors.initials: M
authors.lastname: Muhodin
authors.forename: J
authors.initials: J
authors.lastname: Valentino
authors.forename: J
authors.initials: J
authors.lastname: Herman
authors.forename: P
authors.initials: P
authors.lastname: Desimone
authors.forename: S
authors.initials: S
authors.lastname: Arnold
authors.forename: J
authors.initials: J
authors.lastname: Carrico
authors.forename: A K
authors.initials: AK
authors.lastname: Rockich
authors.forename: J
authors.initials: J
authors.lastname: Warner-Carpenter
authors.forename: M
authors.initials: M
authors.lastname: Barton-Baxter
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems / Q000592:standards; D002985:Clinical Protocols / Q000592:standards; D017321:Clinical Trials, Phase I as Topic / Q000331:legislation & jurisprudence / Q000379:methods / Q000592:standards; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005260:Female; D018014:Gene Transfer Techniques; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis / Q000188:drug therapy* / Q000532:radiotherapy*; D009369:Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D018579:Patient Selection; D014409:Tumor Necrosis Factor-alpha / Q000008:administration & dosage* / Q000009:adverse effects / Q000235:genetics / Q000627:therapeutic use*
chemical_list: D014409:Tumor Necrosis Factor-alpha