title: Computational methods for RNA structure determination.
abstract: During the past year, major improvements have been made in methods used to solve RNA structures from crystals, find RNA patterns in sequence data and determine RNA secondary structure. Computational methods for assisting an interactive computer graphics human modeler, searching the conformational space of RNA tertiary structure, studying the dynamics of complexes involving RNA and simulating RNA catalytic activities have also been advanced.
authors.affiliation: Département d'Informatique et de Recherche Opérationnelle, Université de Montréal, CP 6128, Succ Centre-Ville, Montréal, Québec, H3C 3J7, Canada. major@iro.umontreal.ca
authors.forename: F
authors.initials: F
authors.lastname: Major
authors.forename: R
authors.initials: R
authors.lastname: Griffey
mesh_terms: D001483:Base Sequence; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*
chemical_list: D012313:RNA