title: Asymptomatic leg atherosclerosis is reduced by regular physical activity. Longitudinal results from the cohort "men born in 1914".
abstract: OBJECTIVE
  To study whether physical activity is associated with reduced occurrence of asymptomatic leg atherosclerosis.
  
  
  METHODS
  Longitudinal and cross-sectional analyses of the population-based cohort "men born in 1914".
  
  
  METHODS
  Comparison of the systolic ankle/arm pressure index (AAI) at age 68 in groups who were sedentary, performed some activity, and performed regular physical training at 55 and 68 years of age.
  
  
  RESULTS
  At 55 years of age, 100 (27%) were sedentary, 209 (58%) reported some physical activity and 54 (15%) reported regular physical training. At 68 years, 194 men (53%) reported the same degree of physical activity, 127 (35%) reported a higher physical activity, and 42 (12%) reported lower physical activity. Physical activity at 55 years (p =0.03) and increased physical activity between 55 and 68 years (p =0.03) were both associated with higher AAI at 68 after adjusting for potential confounders. At 68 years, AAI was 0.89+/-0.21, 1.01+/-0.13 and 1.05+/-0.11, respectively, in men who were sedentary, reported some physical activity, and regular physical training (p =0.0002). This association remained significant after adjustments for potential confounders.
  
  
  CONCLUSIONS
  regular physical activity is associated with reduced occurrence of asymptomatic leg atherosclerosis, even in men taking up exercise after age of 55.
authors.affiliation: Division of Epidemiology, Department of Community Medicine, Malmö University Hospital, Lund University, Malmö, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Engström
authors.forename: M
authors.initials: M
authors.lastname: Ogren
authors.forename: B
authors.initials: B
authors.lastname: Hedblad
authors.forename: P
authors.initials: P
authors.lastname: Wollmer
authors.forename: L
authors.initials: L
authors.lastname: Janzon
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001161:Arteriosclerosis / Q000453:epidemiology / Q000517:prevention & control*; D003430:Cross-Sectional Studies; D015444:Exercise; D005500:Follow-Up Studies; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013548:Sweden / Q000453:epidemiology