Wine has activity against entero-pathogenic bacteria in vitro but not in vivo.
We studied the activity of wine against entero-pathogenic bacteria both in vitro and in vivo. The food-borne bacteria were killed in both red and white wine within 30 min. However, the results of a Salmonella infection experiment using mice suggested that wine was not effective in preventing food-borne diseases in vivo.
Sugita-Konishi
Y
Y
Department of Biomedical Food Research, National Institute of Infectious Diseases, Tokyo, Japan. ykonishi@nih.go.jp
Hara-Kudo
Y
Y
Iwamoto
T
T
Kondo
K
K
D000818:Animals; D002478:Cells, Cultured; D004755:Enterobacteriaceae / Q000187:drug effects*; D004847:Epithelial Cells / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D005260:Female; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008826:Microbial Sensitivity Tests; D012480:Salmonella Infections / Q000188:drug therapy* / Q000382:microbiology; D012477:Salmonella enteritidis / Q000187:drug effects; D019108:Tight Junctions / Q000187:drug effects; D014733:Vibrio / Q000187:drug effects; D014920:Wine / Q000032:analysis*