title: Helicobacter pylori infection in the Caribbean: update in management.
abstract: Helicobacter pylori infection of the stomach is one of the commonest chronic infections worldwide and in the Caribbean, over 50% of the population are affected. H pylori is probably transmitted from person to person by oro-faecal and oro-oral means. H pylori is directly associated with peptic ulcer disease, chronic antral gastritis, gastric carcinoma and B-cell lymphoma of the stomach. In patients with peptic ulcers and H pylori infection, eradication of infection with antibiotics significantly decreases recurrence of ulcers. All patients with H pylori related disease should be tested and treated if positive. The treatment of H pylori infection has evolved over the years but at present triple therapy which includes two antibiotics is recommended.
authors.affiliation: Department of Medicine, University at the West Indies, Kingston 7, Jamaica.
authors.forename: M G
authors.initials: MG
authors.lastname: Lee
authors.forename: K O
authors.initials: KO
authors.lastname: Barrow
authors.forename: C N
authors.initials: CN
authors.lastname: Edwards
mesh_terms: D000900:Anti-Bacterial Agents; D017691:Caribbean Region / Q000453:epidemiology; D004359:Drug Therapy, Combination / Q000008:administration & dosage / Q000627:therapeutic use; D016099:Endoscopy, Gastrointestinal; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D016480:Helicobacter pylori; D006801:Humans; D054328:Proton Pump Inhibitors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D054328:Proton Pump Inhibitors