Uterine fibroid embolization: assessment of treatment response using perfusion-weighted extraslice spin tagging (EST) magnetic resonance imaging.
In this pilot study, we demonstrate the feasibility of using an arterial spin tagging technique, Extraslice Spin Tagging (EST), to assess tumor perfusion before and after uterine fibroid embolization (UFE) and correlate the changes in perfusion with fibroid size reduction. We followed two patient volunteers over a six-month period. The perfusion-weighted image intensity decreased immediately after UFE. The size of the tumor decreased by 14% immediately after UFE and continued to decrease over a six-month period to 84%. The imaging methods presented allow for rapid measurement of tumor volume and the evaluation of perfusion of the tumor without the need for intravenous administration of gadolinium compounds. J. Magn. Reson. Imaging 2001;13:982-986.
Hagspiel
K D
KD
Department of Radiology, University of Virginia, Charlottesville, Virginia 22908, USA.
Matsumoto
A H
AH
Berr
S S
SS
D000328:Adult; D004621:Embolization, Therapeutic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D007889:Leiomyoma / Q000098:blood supply* / Q000175:diagnosis / Q000628:therapy; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012039:Regional Blood Flow / Q000502:physiology; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000098:blood supply* / Q000175:diagnosis / Q000628:therapy