title: Apoptosis signaling pathways mediated by cyclooxygenase-2 inhibitors in prostate cancer cells.
authors.affiliation: Division of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536-0082, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Johnson
authors.forename: X
authors.initials: X
authors.lastname: song
authors.forename: A
authors.initials: A
authors.lastname: Hsu
authors.forename: C
authors.initials: C
authors.lastname: Chen
mesh_terms: D017209:Apoptosis; D002118:Calcium / Q000378:metabolism; D000068579:Celecoxib; D002453:Cell Cycle; D002470:Cell Survival; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D053938:DNA Fragmentation; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005434:Flow Cytometry; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D007783:Lactones / Q000494:pharmacology; D008297:Male; D008565:Membrane Proteins; D008956:Models, Chemical; D009578:Nitrobenzenes / Q000494:pharmacology; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000378:metabolism*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D011720:Pyrazoles; D015398:Signal Transduction; D013449:Sulfonamides / Q000494:pharmacology; D013450:Sulfones; D013876:Thiophenes / Q000494:pharmacology; D013997:Time Factors; D014407:Tumor Cells, Cultured; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism
chemical_list: D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D007783:Lactones; D008565:Membrane Proteins; D009578:Nitrobenzenes; D019253:Proto-Oncogene Proteins c-bcl-2; D011720:Pyrazoles; D013449:Sulfonamides; D013450:Sulfones; D013876:Thiophenes; D016159:Tumor Suppressor Protein p53; C116926:rofecoxib; C080955:N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide; C064874:DuP 697; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases; D019869:Phosphatidylinositol 3-Kinases; D000068579:Celecoxib; D002118:Calcium