Silylcupration of 1,3-dienes followed by an electrophilic trapping reaction.
[see reaction]. Silylcupration reaction of 1,3-dienes with a cyanocuprate reagent, PhMe2SiCuCNLi, followed by an electrophilic trapping has been reported for the first time. The use of allylic phosphates as electrophiles resulted in a highly regioselective reaction with overall 1,4-addition of the silyl and allyl moieties across the diene.
Liepins
V
V
Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-10691 Stockholm, Sweden.
Bäckvall
J E
JE