Synthesis of 5,10,15,20-tetrakis(4-tert- butyl-2,6-dicarboxyphenyl)porphyrin: a versatile bis-faced porphyrin synthon for D4-symmetric chiral porphyrins.
[see structure]. A versatile bis-faced porphyrin synthon, 5,10,15,20-tetrakis(4-tert-butyl-2,6-dicarboxyphenyl)porphyrin, was synthesized. The eight carboxyl groups were readily converted into various amide groups, and condensation with chiral amines led to various D4-symmetric chiral porphyrins with rigid structures.
Nakagawa
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Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Nagano
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T
Higuchi
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T