title: Approaches to the assessment of long term exposure to radon and its progeny.
abstract: In recent years, a number of case-control epidemiological studies have taken place and others are in progress to evaluate the lung cancer risk to the general population from exposure to radon and its short-lived progeny in the indoor residential environment. While it is actually long term exposure over past decades to radon progeny by inhalation that dominates lung doses, for a number of practical reasons it is radon gas that is measured in these studies. Because the risk from radon and its progeny results from cumulative exposure over past decades rather than from contemporary exposure, it is necessary to reconstruct the historical exposures of subjects. A number of factors limit the accuracy of this approach of which the following are perhaps the most important: the mobility and residential history of the subjects; radon exposures elsewhere; and changes that may have occurred in the radon levels in current and previous residences. Measurement techniques to assist in making more direct retrospective assessments of radon exposure have appeared in the recent past and are the subject of this paper. These are based on the measurement of the long-lived radon progeny 210Po trapped in household artefacts such as glass or porous and spongy materials. In vivo measurements of skeletal 210Pb in exposed persons is also a method that is currently being investigated as a means to assess historical exposures to radon. The advantages and disadvantages of these methods are described here as well as their potential in future radon epidemiological studies.
authors.affiliation: Department of Experimental Physics, University College Dublin, Ireland. james.mclaughin@ucd.ie
authors.forename: J P
authors.initials: JP
authors.lastname: Mc Laughlin
mesh_terms: D000396:Air Pollutants, Radioactive / Q000009:adverse effects* / Q000032:analysis; D016902:Air Pollution, Indoor / Q000009:adverse effects / Q000032:analysis; D000398:Air Pollution, Radioactive / Q000009:adverse effects / Q000032:analysis; D016022:Case-Control Studies; D004781:Environmental Exposure; D004812:Epidemiologic Methods; D006798:Housing; D006801:Humans; D007856:Lead Radioisotopes / Q000032:analysis; D011059:Polonium / Q000032:analysis; D011886:Radon / Q000009:adverse effects* / Q000032:analysis; D017687:Radon Daughters / Q000009:adverse effects / Q000032:analysis; D013997:Time Factors
chemical_list: D000396:Air Pollutants, Radioactive; D007856:Lead Radioisotopes; D017687:Radon Daughters; D011059:Polonium; D011886:Radon