title: Adenosine- and verapamil-sensitive ventricular tachycardia in the newborn.
abstract: Two neonates presented with sustained, monomorphic VT. Transesophageal electrophysiological studies demonstrated that the VTs were initiated with burst atrial pacing in one and noninducible in the other, and both terminated with burst atrial pacing and with adenosine. Oral verapamil suppressed the VTs in both. Following discontinuation of verapamil at 1 year of age, both children remain free of tachycardia recurrence at 3 and 4 years of age. These cases suggest that cAMP-mediated triggered activity may be responsible for some VTs in infancy.
authors.affiliation: Department of Pediatric Cardiology, Hacettepe University, Faculty of Medicine, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Ozer
authors.forename: S
authors.initials: S
authors.lastname: Allen
authors.forename: M S
authors.initials: MS
authors.lastname: Schaffer
mesh_terms: D000241:Adenosine / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004562:Electrocardiography; D004594:Electrophysiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D017180:Tachycardia, Ventricular / Q000175:diagnosis / Q000188:drug therapy*; D014700:Verapamil / Q000627:therapeutic use*
chemical_list: D000889:Anti-Arrhythmia Agents; D014700:Verapamil; D000241:Adenosine