title: A new diterpene from Hypoestes serpens.
abstract: From a defatted chloroform extract of the aerial parts of Hypoestes serpens a new diterpene exhibiting relaxant activity on isolated rat aorta was obtained. The structure of this compound, named serpendione (1), was fully established by the interpretation of its spectral data.
authors: Faculté des Sciences, Université d'Antananarivo, B.P. 906, 101-Antananarivo, Madagascar, Institut de Chimie des Substances Naturelles (ICSN-CNRS), Avenue de la Terrasse, 91198-Gif-sur-Yvette, France.
authors: B
authors: B
authors: Andriamihaja
authors: M T
authors: MT
authors: Martin
authors: P
authors: P
authors: Rasoanaivo
authors: F
authors: F
authors: Frappier
mesh_terms: D000818:Animals; D001011:Aorta / Q000187:drug effects; D002725:Chloroform; D034242:Cyclooctanes; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D008956:Models, Chemical; D009126:Muscle Relaxation / Q000187:drug effects*; D051381:Rats; D013055:Spectrophotometry, Infrared; D014664:Vasodilation / Q000187:drug effects*; D014665:Vasodilator Agents / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D034242:Cyclooctanes; D004224:Diterpenes; D014665:Vasodilator Agents; C433581:serpendione; D002725:Chloroform