Two new podophyllotoxin glucosides from Sinopodophyllum emodi (Wall.) Ying.
Two new aryltetralin-type lignans, isopodophyllotoxin 7'-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (1) and 4-demethyl-picropodophyllotoxin 7'-O-beta-D-glucopyranoside (2), along with eight known podophyllotoxin derivatives: 4-demethyl-podophyllotoxin 7'-O-beta-D-glucopyranoside (3), podophyllotoxin 7'-O-beta-D-glucopyranoside (4), deoxypodophyllotoxin (5), picropodophyllotoxin (6), podophyllotoxin (7), 4-demethyl-picropodophyllotoxin (8), 4-demethyl-podophyllotoxin (9), and 4-demethyl-deoxypodophyllotoxin (10), were isolated from the roots and rhizomes of Sinopodophyllum emodi (Wall.) Ying (Berberidaceae). Their structures were identified based on NMR spectral data and chemical evidence.
Zhao
C
C
Faculty of Pharmaceutical Sciences, Nagoya City University, Japan.
Huang
J
J
Nagatsu
A
A
Ogihara
Y
Y
D005960:Glucosides; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification*; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D011034:Podophyllotoxin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D013057:Spectrum Analysis
C440054:4-demethyl-picropodophyllotoxin 7'-O-glucopyranoside; D005960:Glucosides; D017705:Lignans; C440053:isopodophyllotoxin 7'-O-glucopyranosyl-(1-6)-glucopyranoside; D011034:Podophyllotoxin