[Small cell lung cancer revealed by extramembranous glomerulonephritis].
We describe a case of small-cell lung cancer limited to the thorax but with malignant pleural effusion in a 47-year-old man that was revealed by a nephrotic syndrome due to membranous glomerulonephritis (MGN). Chemotherapy led to a partial tumor response with total resolution of the nephrotic syndrome. Tumor relapse did not provoke proteinuria. Primary lung cancer is the cause of about 3% of all cases of MGN and 40% of tumor-related MGN. There are 49 cases of tumor-related MGN in the literature, including 9 cases of small-cell lung cancer.
Grivaux
M
M
Service de Pneumologie, Centre Hospitalier de Meaux, 6-8 rue St Fiacre, BP 218, 77104 Meaux. pneumomeaux@csi.com ou m-grivaux@ch-meaux.fr
Renault
D
D
Gallois
J C
JC
Barbanel
C
C
Blanchon
F
F
D000970:Antineoplastic Agents / Q000627:therapeutic use; D018288:Carcinoma, Small Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015433:Glomerulonephritis, Membranous / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D016066:Pleural Effusion, Malignant / Q000209:etiology / Q000473:pathology; D011379:Prognosis; D011507:Proteinuria / Q000209:etiology
D000970:Antineoplastic Agents