title: [Infantile bilateral striate necrosis].
abstract: BACKGROUND
  Necrosis of the basal ganglia (NBG) is an uncommon condition in childhood. Cases of NBG have been reported in connection with metabolic disorders, infections, degenerative conditions, intoxications, head injuries and hypoxic-ischemic encephalopathies. The commonest clinical features include alteration of consciousness, chorea-athetoic or dystonic movements, spasticity, contractures of the limbs and convulsions.
  
  
  METHODS
  We describe the case of an eight year old girl, who after having clinical gastroenteritis, developed acute neurological dysfunction, associated with images on cranial computerized axial tomography (CAT) showing a possible intracranial tumour and magnetic resonance (MR) studies showing bilateral hypodensity of the basal ganglia. Three months later magnetic resonance showed that these lesions had almost completely disappeared. This supports the diagnosis of post-infectious lesions.
  
  
  CONCLUSIONS
  The clinical course is very variable. Cases with a previous history of infection have a better prognosis. In our patient treatment was started with corticosteroids. She made a good recovery and was sent home with no sequelae five days later. The new imaging techniques (CAT and MR) have led to more cases of selective involvement of the basal ganglia being diagnosed. MR is the most specific technique for diagnosis in these patients. Although there is no effective specific treatment, treatment with biperidine, thyrotropic hormone and corticosteroids have been used with no apparent effect on the course of the disorder.
authors: Cuidados Intensivos Pediátricos.Medicina Intensiva; Hospital General Universitario de Alicante, Alicante, 03010, España. nurico@jazzfree.com
authors: P
authors: P
authors: Garcés
authors: A R
authors: AR
authors: Reyes
authors: R
authors: R
authors: Reig
authors: E
authors: E
authors: Martínez
authors: S
authors: S
authors: Alonso
authors: R
authors: R
authors: Carrasco
mesh_terms: D001480:Basal Ganglia Diseases / Q000150:complications / Q000382:microbiology / Q000473:pathology; D002648:Child; D003342:Corpus Striatum / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000473:pathology*; D004569:Electroencephalography; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000276:immunology; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D008279:Magnetic Resonance Imaging; D009336:Necrosis; D012120:Respiration Disorders / Q000209:etiology / Q000534:rehabilitation; D012121:Respiration, Artificial; D014057:Tomography, X-Ray Computed
chemical_list: D007074:Immunoglobulin G