[Analysis of filtration according to implant type after deep sclerectomy in the rabbit].
OBJECTIVE
The purpose of this study was to compare the aqueous humor outflow using three type of implants after deep sclerectomy. A numeric imaging system with ICG and fluorescein angiography was used. The evolution over time was recorded, while filtration and outflow facility were measured.


METHODS
Numeric imaging system with ICG and fluorescein angiography were performed before and after deep sclerectomy at regular intervals after surgery. Both resorbable (collagen) and non-resorbable (hema) intrascleral devices have been tested in eight rabbits. The resorption time of the collagen implants has been monitored using UBM technique. The outflow facility was measured with the technique of anterior chamber canulation and constant pressure method.


RESULTS
The resorbable collagen implants could be observed with UBM and angiography during the first six weeks post-operatively. The image of the non-resorbable Hema implant remained clearly visible over time. New drainage vessels were observed around the filtering bleb. The filtration significantly increased as the outflow facility improved after surgery, while the intraocular pressure remained stable over time.


CONCLUSIONS
This conjunction of UBM, angiography and outflow measurement allowed us to study and compare three types of implants used as space maintainer after deep sclerectomy, and analyse their effect on the aqueous filtration and outflow facility.
Roy
S
S
Hôpital ophtalmique Jules Gonin, Av de France 15, CH-1004 Lausanne.
Boldea
R
R
Nguyen
C
C
Perez
D
D
Curchod
M
M
Mermoud
A
A
D000818:Animals; D001082:Aqueous Humor / Q000502:physiology*; D003094:Collagen; D004867:Equipment Design; D005451:Fluorescein Angiography; D007208:Indocyanine Green; D007429:Intraocular Pressure / Q000502:physiology*; D018465:Molteno Implants; D011817:Rabbits; D012599:Sclerostomy / Q000379:methods*
D003094:Collagen; D007208:Indocyanine Green