Breast milk beta-glucuronidase levels in hyperbilirubinemia.
Breast milk beta-glucuronidase was thought to be one of the etiological factors in the pathogenesis of late-onset breast-milk jaundice, but results of these studies are conflicting. In this study breast milk beta-glucuronidase levels were determined in groups with physiologic jaundice, early breast-feeding jaundice and late breast-milk jaundice. No difference in beta-glucuronidase levels of these three groups was found in samples taken on the 4th and 15th days of life. beta-glucuronidase activity in breast milk declined from the 4th to 15th day in all groups. These results imply that factors other than breast milk beta-glucuronidase activity should be investigated to reveal the pathogenesis of late-onset breast-milk jaundice.
Yiğit
S
S
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Ciliv
G
G
Aygün
C
C
Erdem
G
G
D005966:Glucuronidase / Q000378:metabolism*; D006801:Humans; D006932:Hyperbilirubinemia / Q000503:physiopathology*; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000503:physiopathology*; D008895:Milk, Human / Q000201:enzymology*
D005966:Glucuronidase