title: Cancer chemopreventive agents. New depsidones from Garcinia plants.
abstract: In a search for cancer chemopreventive agents from natural sources, chemical constituents of two kinds of Garcinia plants, Garcinia neglecta and Garcinia puat, collected in New Caledonia, were examined. Five new depsidones, garcinisidone-B (2), -C (3), -D (4), -E (5), and -F (6), were isolated, and their structures were determined by spectrometric analyses. Inhibitory effects of these depsidones on EBV-EA activation induced by TPA in Raji cells were also demonstrated.
authors: Faculty of Pharmacy, Meijo University, Tempaku, Nagoya 468-8503, Japan.
authors: C
authors: C
authors: Ito
authors: M
authors: M
authors: Itoigawa
authors: Y
authors: Y
authors: Mishina
authors: H
authors: H
authors: Tomiyasu
authors: M
authors: M
authors: Litaudon
authors: J P
authors: JP
authors: Cosson
authors: T
authors: T
authors: Mukainaka
authors: H
authors: H
authors: Tokuda
authors: H
authors: H
authors: Nishino
authors: H
authors: H
authors: Furukawa
mesh_terms: D016588:Anticarcinogenic Agents; D000956:Antigens, Viral / Q000378:metabolism; D053630:Depsides; D020448:Ericales / Q000737:chemistry*; D004988:Ethers, Cyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004854:Herpesvirus 4, Human / Q000187:drug effects; D006801:Humans; D007783:Lactones; D008956:Models, Chemical; D009510:New Caledonia; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D016588:Anticarcinogenic Agents; D000956:Antigens, Viral; D053630:Depsides; C033305:Epstein-Barr virus early antigen; D004988:Ethers, Cyclic; D007783:Lactones; D010936:Plant Extracts; C000875:depsidone; D013755:Tetradecanoylphorbol Acetate