Non-Epstein-Barr virus-associated T-cell lymphoma following cardiac transplantation for Barth syndrome.
Barth syndrome is a metabolic disease characterized by infantile cardiomyopathy, neutropenia and organic aciduria. We report disease evolution in one of the first affected boys to undergo successful cardiac transplantation.


CONCLUSIONS
Although cardiac status stabilized, he developed disabling skeletal myopathy, protracted lymphopenia and--5 y after transplant--fatal Epstein Barr (EBV)-negative T-cell non-Hodgkin's lymphoma.
Ronghe
M D
MD
Department of Haematology/Oncology, Royal Hospital for Sick Children, St. Michael's Hill, Bristol, UK. M.D.Ronghe@bristol.ac.uk
Foot
A B
AB
Martin
R
R
Ashworth
M
M
Steward
C G
CG
D002311:Cardiomyopathy, Dilated / Q000601:surgery*; D017809:Fatal Outcome; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007223:Infant; D016411:Lymphoma, T-Cell, Peripheral / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D013577:Syndrome