Novel IFN-alpha receptor promoter polymorphisms.
We have identified two single nucleotide polymorphisms and one dinucleotide microsatellite within the promoter region of the interferon-alpha receptor gene (IFNAR, GenBank accession number X60459). Allele frequencies in a Caucasian population were established using PCR-RFLP for the two SNPs and semi-automated genotyping for the microsatellite.
Muldoon
J
J
ARC Epidemiology Unit, School of Epidemiology and Health Sciences, University of Manchester, Oxford Road, Manchester, UK.
Uriel
A
A
Khoo
S
S
Ollier
W E
WE
Hajeer
A H
AH
D000483:Alleles; D005787:Gene Frequency; D006801:Humans; D007370:Interferon Type I; D008565:Membrane Proteins; D018895:Microsatellite Repeats / Q000235:genetics; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic; D053633:Receptor, Interferon alpha-beta; D017471:Receptors, Interferon / Q000235:genetics*; D006113:United Kingdom; D044465:White People
C507964:IFNAR1 protein, human; D007370:Interferon Type I; D008565:Membrane Proteins; D017471:Receptors, Interferon; D053633:Receptor, Interferon alpha-beta