title: Evaluation of the biological activity of crude extracts from plants used in Yucatecan traditional medicine. Part II. DNA-interacting activity.
abstract: Extracts from leaves, stems, and roots of twelve plants used commonly in Yucatecan traditional medicine were evaluated in the DNA-methyl green assay. Twenty one extracts showed DNA-interacting activity, and nine of them, belonging to five plant species, presented a displacement activity of 5% or higher. The highest activity (17.6%) was detected in the leaf extract of Heliotropium angiospermum.
authors: Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, Mérida, México.
authors: A
authors: A
authors: Sánchez-Medina
authors: K
authors: K
authors: García-Sosa
authors: F
authors: F
authors: May-Pat
authors: L M
authors: LM
authors: Peña-Rodríguez
mesh_terms: D004247:DNA / Q000187:drug effects*; D004353:Drug Evaluation, Preclinical; D004996:Ethidium / Q000494:pharmacology; D008519:Medicine, Traditional; D008739:Methyl Green; D008800:Mexico; D008954:Models, Biological; D010598:Pharmacognosy; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D018514:Plant Structures; D010946:Plants, Medicinal
chemical_list: D010936:Plant Extracts; D008739:Methyl Green; D004247:DNA; D004996:Ethidium