[Value of indocyanine green angiography in detection of central serous chorioretinopathy].
BACKGROUND
Central serous chorioretinopathy (CSC) is a relatively common and self-limited disease affecting more commonly young adult males who are likely to have a type A personality. The aim of our study was to analyze indocyanine green (ICG) angiographic findings in CSC and correlate them with the biomicroscopical and Fluoresceine angiography (FA) findings in the affected and non affected eyes.


METHODS
Our study included 19 consecutive patients, that were affected by CSC. The mean age of the patients was 44 years (range 35-50 years). In thirteen patients, in one eye typical acute lesions were observed, and in six patients presented chorioretinal inactive lesions. Angiographic ICG and FA findings of both eyes were compared.


RESULTS
In 13 eyes (68%) presenting with the active form of CSC a classic focal leak with a smokestack phenomenon was seen in FA. The leaking point was identified in both FA and ICG, in 9 out of 13 eyes (70%). Surrounding the FA leaking point, an hyperfluorescent plaque in ICG was associated in 12 out of 13 (92%) eyes with active lesions. In 8 out of 13 (62%) controlateral eyes of this group, hyperfluorescent plaques in ICG were also observed. All eyes with inactive FA lesions (6 out of 6), expressed an hyperfluorescent plaque in ICG.


CONCLUSIONS
ICG hyperfluorescence appears in the affected and the fellow eyes in areas where no clinical or FA signs of active disease were present. The persistence of abnormal ICG findings in all the cases of inactive disease suggest that CSC could be not a recurrent but a chronic disease.
Katsimpris
J
J
Clinique d'Ophtalmologie, Département des Neurosciences Cliniques, Hôpitaux universitaires Genevois, Suisse.
Donati
G
G
Kapetanios
A
A
Pharmakakis
N
N
Pournaras
C J
CJ
D000328:Adult; D002825:Chorioretinitis / Q000175:diagnosis*; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity
D007208:Indocyanine Green