Granulatimide and 6-bromogranulatimide, minor alkaloids of the Brazilian ascidian Didemnum granulatum.
Reinvestigation of the extract of the ascidian Didemnum granulatum collected on the Brazilian coastline led to the isolation of two minor compounds, granulatimide (2) and 6-bromogranulatimide (3), which have been identified by analysis of their spectroscopic data. The isolation of 2 and 3 from D. granulatum corroborates previous assumptions about the occurrence of granulatimide as a natural product.
Britton
R
R
Instituto de Química de São Carlos, Universidade de São Paulo, CP 780, CEP 13560-970, São Carlos, SP, Brazil.
de Oliveira
J H
JH
Andersen
R J
RJ
Berlinck
R G
RG
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D001938:Brazil; D008956:Models, Chemical; D014561:Urochordata / Q000737:chemistry*
C433588:6-bromogranulatimide; D000470:Alkaloids; C433587:granulatimide