Procedures for estimating confidence intervals for selected method performance parameters.
Procedures for estimating confidence intervals (CIs) for the repeatability variance (sigmar2), reproducibility variance (sigmaR2 = sigmaL2 + sigmar2), laboratory component (sigmaL2), and their corresponding standard deviations sigmar, sigmaR, and sigmaL, respectively, are presented. In addition, CIs for the ratio of the repeatability component to the reproducibility variance (sigmar2/sigmaR2) and the ratio of the laboratory component to the reproducibility variance (sigmaL2/sigmaR2) are also presented.
McClure
F D
FD
US Department of Health and Human Services, Food and Drug Administration, Washington, DC 20204, USA.
Lee
J K
JK
D000704:Analysis of Variance; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D007753:Laboratories / Q000592:standards; D015233:Models, Statistical; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic