[Efficacy of modified ultrafiltration in coronary artery bypass grafting].
We evaluated the efficacy of modified ultrafiltration (MUF) in coronary artery bypass grafting. Twenty patients were divide into two groups consisting of a control group (n = 11) and a MUF group (n = 9). MUF was carried out for fifteen minutes immediately after the completion of cardiopulmonary bypass. The blood flow through the ultrafilter was 300 ml/min and about 1,200 ml of water was removed. The hematocrit elevated significantly from 25% to 30% in the MUF group (p < 0.01). Postoperative blood loss in the first 24 hours in the MUF group was significantly less than that in the control group (8 +/- 2 ml/kg vs 12 +/- 4 ml/kg, p < 0.01). There was no statistical difference in the percentage of the increase in body weight after the operation, inflammatory reaction and pulmonary function (A-a DO2, PaO2/FIO2 and duration of intubation) between two groups. In conclusion, MUF is useful to hemoconcentrate and reduce postoperative blood loss in coronary artery bypass grafting.
Kamada
M
M
Department of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Niibori
K
K
Akimoto
H
H
Yokoyama
H
H
Tofukuji
M
M
Iguchi
A
A
Ohmi
M
M
Tabayashi
K
K
Kikuchi
S
S
Matsuura
T
T
D000368:Aged; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D001026:Coronary Artery Bypass; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery; D006400:Hematocrit; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation