title: Exercise-induced bronchoconstriction among Malay schoolchildren.
abstract: OBJECTIVE
  Exercise-induced bronchoconstriction (EIB) may be demonstrated in 60-70% of asthmatic children in temperate climates. In areas of high humidity it is postulated to be low. The aim of the study was to determine the prevalence of EIB in a population of schoolchildren with wheezing, living in the humid tropical climate of Kuala Lumpur, Malaysia.
  
  
  METHODS
  We performed a cross-sectional study using the International Study of Asthma and Allergies in Childhood questionnaire to identify 7-12-year-old Malay children with asthma symptoms from a primary school in central Kuala Lumpur. Sixty-five of 76 children with 'ever wheeze' performed an exercise challenge test successfully in an uncontrolled environment. A random sample of 80 schoolchildren with no history of wheeze were similarly tested as controls. The relative humidity and temperature were recorded. A fall of > 15% was considered as clinically important.
  
  
  RESULTS
  The prevalence of EIB in schoolchildren with 'ever wheeze' was 47.7%. The prevalence of EIB in children with 'current wheeze' was 51.6%. The prevalence of EIB in controls was 7.5%. The relative humidity during the study ranged from 41 to 90%. There was no significant relationship between different humidity levels and EIB (P = 0.58, regression analysis).
  
  
  CONCLUSIONS
  This study demonstrates that EIB is present in asthmatic children despite the highly humid tropical environment.
authors: Department of Paediatrics, Institut Pediatrik, Hospital Kuala Lumpur, Malaysia. norzila@crc.jaring.my
authors: N M
authors: NM
authors: Zainudin
authors: B A
authors: BA
authors: Aziz
authors: A L
authors: AL
authors: Haifa
authors: C T
authors: CT
authors: Deng
authors: A H
authors: AH
authors: Omar
mesh_terms: D001250:Asthma, Exercise-Induced / Q000453:epidemiology* / Q000473:pathology; D002648:Child; D003430:Cross-Sectional Studies; D005080:Exercise Test; D005260:Female; D006801:Humans; D006813:Humidity; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D012044:Regression Analysis; D012129:Respiratory Function Tests; D012135:Respiratory Sounds / Q000503:physiopathology; D014329:Tropical Climate