A link between psychosocial factors and blood pressure trend in women.
The powerful effect of psychosocial and acculturating influences on population blood pressure trends seems to be confirmed, through longitudinal observations, in the nuns in a secluded order. After initial observation had been made on culture, body form, blood pressure, diet, and other variables in 144 nuns and 138 laywomen, included as a control group, a 32-year follow-up study was undertaken. Most striking were opposite trends noted between the two groups in blood pressure trend. During the follow-up period blood pressure remained remarkably stable among the nuns. None showed a rise in diastolic blood pressure to above 90 mmHg. By contrast the control women showed the expected increase in blood pressure with age. This resulted in a gradually greater difference (Delta>30/15 mmHg) in systolic and diastolic blood pressure between the two groups, which was statistically significant. Fatal and nonfatal events were exceedingly lower in the nuns than in the control women over the follow-up period. It appears reasonable to attribute much of the difference in blood pressure to the different burden in psychosocial factor and to the preserved peaceful lifestyle of the nuns.
Timio
M
M
Department of Internal Medicine and Nephrology, Teaching Hospital, Foligno, Italy. timma@libero.it
Saronio
P
P
Verdura
C
C
Schiaroli
M
M
Timio
F
F
Monarca
C
C
D000328:Adult; D000375:Aging / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000523:psychology; D002395:Catecholamines / Q000652:urine; D002784:Cholesterol / Q000097:blood; D004651:Employment; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D011188:Potassium / Q000652:urine; D012931:Social Environment; D012964:Sodium / Q000652:urine; D014280:Triglycerides / Q000097:blood
D002395:Catecholamines; D014280:Triglycerides; D002784:Cholesterol; D012964:Sodium; D011188:Potassium