title: Comparison of two positive reinforcing stimuli: pups and cocaine throughout the postpartum period.
abstract: This set of experiments investigated the appetitive or motivational processes underlying the performance of maternal behavior. The place preference paradigm was adapted to simultaneously investigate the reinforcing properties of cocaine and pups for maternal, lactating dams. These modifications allowed the authors to assess which stimulus, either a 10 mg/kg s.c. injection of cocaine or 3 pups, had the strongest reinforcing value. At Postpartum Days 10 and 16, the dams preferred the cocaine cue-associated chamber, whereas the dams tested at Postpartum Day 8 preferred the pup cue-associated chamber. Overall, the data revealed an interaction between the postpartum period at testing and the exhibited preference for cocaine or pups. Further testing will investigate the neural circuitry underlying the appetitive processes of each stimulus.
authors: Behavioral Neuroscience, Rutgers, State University of New Jersey, 197 University Avenue, Newark, New Jersey 07102, USA. mattson@axon.rutgers.edu
authors: B J
authors: BJ
authors: Mattson
authors: S
authors: S
authors: Williams
authors: J S
authors: JS
authors: Rosenblatt
authors: J I
authors: JI
authors: Morrell
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002755:Choice Behavior; D003042:Cocaine / Q000494:pharmacology*; D005260:Female; D008425:Maternal Behavior; D009042:Motivation; D011247:Pregnancy; D051381:Rats; D017207:Rats, Sprague-Dawley; D012054:Reinforcement, Psychology; D012931:Social Environment
chemical_list: D003042:Cocaine