title: [Respiratory bronchiolitis with diffuse interstitial lung disease].
abstract: Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) is a disease that exclusively affects cigarette smokers. Long-term prognosis is good with cessation of smoking, in combination or not with corticosteroid therapy. We report here the case of a 50-year-old patient with RB-IL diagnosed on lung biopsy. Despite corticosteroid and cyclophosphamide therapy, no functional or radiological improvement was obtained. In contrast, cessation of smoking was associated with the disappearance of the infiltrative opacities. Clinical and radiological parameters remained stable during follow-up (13 years) while a moderate obstructive pattern appeared.
authors: Clinique des Maladies Respiratoires, Hôpital A. Calmette, CHRU, 59037 Lille.
authors: A
authors: A
authors: Prigent
authors: C
authors: C
authors: Lamblin
authors: M C
authors: MC
authors: Copin
authors: B
authors: B
authors: Wallaert
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001988:Bronchiolitis / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D017563:Lung Diseases, Interstitial / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide