N-(tert-butoxycarbonyl)-N-[4-(dimethylazaniumylidene)-1,4-dihydropyridin-1-ylsulfonyl]azanide: a new sulfamyolating agent. Structure and reactivity toward amines.
[structure: see text] Synthesis, structure, and reactivity toward amines of the new sulfamoylating reagent 2 are described. Compound 2 allowed sulfamoylation of amines under very mild conditions to give sulfamide derivatives in good yields.
Winum
J Y
JY
Laboratoire de Chimie Biomoléculaire, UMR 5032, Université Montpellier II, Ecole Nationale Supérieure de Chimie de Montpellier, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex, France. winumj@crit.univ-montp2.fr
Toupet
L
L
Barragan
V
V
Dewynter
G
G
Montero
J L
JL
D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D004095:Dihydropyridines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000737:chemistry*
D000588:Amines; D004095:Dihydropyridines; C432705:N-(tert-butoxycarbonyl)-N-(4-(dimethylazaniumylidene)-1,4-dihydropyridin-1-ylsulfonyl)azanide; D013449:Sulfonamides