Antioxidant activity of water-soluble chitosan derivatives.
Water-soluble chitosan derivatives were prepared by graft copolymerization of maleic acid sodium onto hydroxypropyl chitosan and carboxymethyl chitosan sodium. Their scavenging activities against hydroxyl radical *OH were investigated by chemiluminescence technique. They exhibit IC(50) values ranging from 246 to 498 microg/mL, which should be attributed to their different contents of hydroxyl and amino groups and different substituting groups.
Xie
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W
Department of Chemistry, Yuquan Campus, Zhejiang University, 310027, Hangzhou, China.
Xu
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P
Liu
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Q
D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D002686:Chitin / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology*; D048271:Chitosan; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology*; D017665:Hydroxyl Radical; D012995:Solubility; D014867:Water
D000975:Antioxidants; D016166:Free Radical Scavengers; D014867:Water; D002686:Chitin; D017665:Hydroxyl Radical; D048271:Chitosan