title: Bacterial transporters for sulfate and organosulfur compounds.
abstract: Microorganisms require sulfur for growth, and obtain it either from inorganic sulfate or from organosulfur compounds such as sulfonates, sulfate esters, or sulfur-containing amino acids. Transport of sulfate into the cell is catalyzed either by ATP binding cassette (ABC)-type transporters (SulT family) or by major facilitator superfamily-type transporters (SulP family). By contrast, the sulfonate and sulfate ester transporters identified to date are all ABC-type systems, whose synthesis is tightly regulated by the sulfur supply to the cell, mediated by the CysB protein and other transcriptional regulators of the LysR-family.
authors: School of Biological Sciences, University of Manchester, UK. michael.kertesz@man.ac.uk
authors: M A
authors: MA
authors: Kertesz
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000378:metabolism; D026905:Amino Acid Transport Systems / Q000378:metabolism; D001419:Bacteria / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism; D001692:Biological Transport; D026901:Membrane Transport Proteins / Q000378:metabolism*; D011485:Protein Binding; D013429:Sulfatases / Q000737:chemistry / Q000378:metabolism; D013431:Sulfates / Q000737:chemistry / Q000378:metabolism*; D013455:Sulfur / Q000378:metabolism*
chemical_list: D018528:ATP-Binding Cassette Transporters; D026905:Amino Acid Transport Systems; D001426:Bacterial Proteins; D026901:Membrane Transport Proteins; D013431:Sulfates; D013455:Sulfur; D013429:Sulfatases