Succimer for treatment of lead toxicosis in two cats.
Two cats from a single household were examined because of neurologic abnormalities suggestive of central vestibular disease. The owner had been renovating her 150-year-old house for the preceding 3 months, and renovations included chipping and sanding of old paint from windowsills and stair railings. Lead toxicosis was diagnosed on the basis of history and concentrations of lead in blood and urine. Both cats were treated with succimer. Treatment was not associated with any adverse effects, and both cats recovered completely. Ingestion of old paint from house renovations is the most common source of lead exposure in cats. Owners of cats with gastrointestinal tract or neurologic abnormalities should be questioned specifically about house renovations.
Knight
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TE
Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
Kent
M
M
Junk
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JE
D000818:Animals; D000855:Anorexia / Q000662:veterinary; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D002614:Chelating Agents / Q000627:therapeutic use*; D005260:Female; D007668:Kidney / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D007854:Lead / Q000097:blood / Q000493:pharmacokinetics / Q000652:urine; D007855:Lead Poisoning / Q000188:drug therapy / Q000662:veterinary*; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D012640:Seizures / Q000662:veterinary; D004113:Succimer / Q000627:therapeutic use*; D014018:Tissue Distribution; D014839:Vomiting / Q000662:veterinary
D002614:Chelating Agents; D007854:Lead; D004113:Succimer