MMR vaccine in HIV-infected children -- potential hazards?
Although given routinely as prophylaxis against wild-type measles to HIV-infected children, the live attenuated measles component of the MMR triple vaccine also possesses potential for disease. We document a case of measles proven to be caused by vaccine strain in a HIV-infected child here in the UK and discuss the clinical and immunological aspects. We also consider the new guidelines for MMR vaccination in HIV-infected children adopted last year in the USA.
Goon
P
P
Imperial College School of Medicine at St. Mary's, Norfolk Place, London W2 1PG, UK. p.goon@ic.ac.uk
Cohen
B
B
Jin
L
L
Watkins
R
R
Tudor-Williams
G
G
D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D002648:Child; D000075202:Contraindications; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007223:Infant; D008297:Male; D008457:Measles / Q000209:etiology; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D017410:Practice Guidelines as Topic; D006113:United Kingdom; D014481:United States
D022542:Measles-Mumps-Rubella Vaccine