[Remote sequelae of combined influence of vinyl chloride and dichloroethane (experimental study)].
Exposure to concentrations of vinyl chloride (VC) + dichloroethane (DCE) 50 + 50 mg/m3, VC + DCE 50 + 500 mg/m3 and VC + DCE 500 + 50 mg/m3 during pregnancy induced higher occurrence of fetal resorption, increased incidence of preimplantational and postimplantational fetal death. Carcinogenic activity of the same levels of VC and DCE was seen in various organs: high concentrations of DCE increased incidence of lung tumors, high levels of VC--of breast neoplasms, mesenterial lymphosarcoma and liver hemangiosarcoma.
Lemeshevskaia
E P
EP
Savchenkov
M V
MV
Benemanskiĭ
V V
VV
Katul'skiĭ
Iu N
IuN
Zhukova
E V
EV
Pankratov
I P
IP
Lemeshevskaia
M V
MV
D000818:Animals; D004195:Disease Models, Animal; D005025:Ethylene Dichlorides / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006394:Hemangiosarcoma / Q000139:chemically induced*; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced*; D009784:Occupational Diseases / Q000139:chemically induced*; D051381:Rats; D014752:Vinyl Chloride / Q000009:adverse effects*
D005025:Ethylene Dichlorides; D014752:Vinyl Chloride