[The origin of femoral trochlear dysplasia: comparative anatomy, evolution, and growth of the patellofemoral joint].
We performed a comparative analysis of the femoropatellar morphology examining the evolutionary aspects to search for the origin of trochelar dysplasia. Trochlear dysplasia is frequent in the human population and, when associated with morphological and positional abnormalities of the patella, can lead to patellar pain syndrome in minor cases or patellar dislocation in severe cases. There is no strict relationship between the observed anomalies and clinical expression. The shape of the articular surfaces is variable in mammals depending on their type of locomotion: unguligrade, digitigrade, plantigrade. In greater apes, the femoral diaphysis is straight and the trochlea is flat and symmetrical. The patella does not tend to dislocate laterally since the knee under load is always flexed. In human adults, the femoral diaphysis has a valgus obliquity angle of 8 degrees to 10 degrees. Consequently, the trochlea has a deepened sulcus and an elevated lateral lip, avoiding lateral patellar dislocation, especially during initial knee flexion. In the human newborn, the femoral diaphysis is vertical. As the child starts walking, the femoral obliquity angle develops between 1 and 7 years of age, inducing a secondary valgus of the extensor apparatus. This obliquity does not develop in non-walking children. Fossil femurs of australopithecus demonstrate that a high obliquity angle had appeared more than 3 million years ago, but also exhibit a poorly deepened trochlea and a slight elevation of the lateral facet. At 1.8 million years, the fossils have the oblique diaphysis, the strongly deepened sulcus and the strongly elevated lateral facet. The obliquity angle of the femoral diaphysis is the leading feature which initiated the later modifications of the patellofemoral joint that over 3 million years were never inscribed in the human genoma. Lateral trochleal lip and deep sulcus are features that were first acquired, then once selected, genetically assimilated, and now appear on the fetal cartilaginous epiphysis.
Tardieu
C
C
CNRS UMR 8570, Laboratoire d'Anatomie Comparée, Muséum National d'Histoire Naturelle, 55, rue Buffon, 75005 Paris. tardieu@mnhn.fr
Dupont
J Y
JY
D000328:Adult; D000818:Animals; D005075:Biological Evolution; D001696:Biomechanical Phenomena; D001848:Bone Diseases, Developmental / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005314:Embryonic and Fetal Development; D005269:Femur / Q000254:growth & development* / Q000473:pathology*; D005580:Fossils; D005684:Gait; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007719:Knee Joint / Q000254:growth & development* / Q000473:pathology*; D008322:Mammals / Q000033:anatomy & histology*; D010329:Patella / Q000254:growth & development* / Q000473:pathology*; D011187:Posture; D011859:Radiography; D016059:Range of Motion, Articular; D016138:Walking