Leptin and HDL-cholesterol in non-diabetic normotensive subjects.
BACKGROUND
We investigated the relationships between body mass index (BMI), serum leptin and serum HDL-cholesterol.


METHODS
A retrospective study was carried out in 80 patients who did not have type 2 diabetes mellitus and/or high blood pressure.


RESULTS
Both serum leptin and HDL-cholesterol serum levels correlated with BMI (r = 0.616 and r = -0.269, respectively), but when the BMI values were kept constant no correlation was found between serum leptin and HDL-cholesterol both in simple and in multiple regression.


CONCLUSIONS
The findings suggest that serum leptin concentration is completely independent of lipid metabolism.
Marinari
G M
GM
Dipartimento di Discipline Chirurgiche e Metodologie Integrate, Università di Genova, Italy.
Scopinaro
N
N
Adami
G F
GF
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood*; D005260:Female; D006801:Humans; D020738:Leptin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D012189:Retrospective Studies
D008076:Cholesterol, HDL; D020738:Leptin