Anaesthetic management of 27 cases of boron neutron capture therapy for glioblastoma.
Twenty-seven patients received boron neutron capture therapy during craniotomy at our research reactor from 1991 to 1999. This is a form of intra-operative radiation therapy, which uses neutrons from a nuclear reactor. There are three additional major problems to anaesthetists: boron neutron capture therapy must be given beside the nuclear reactor, with no hospital facilities; neutrons cannot be shielded effectively by ordinary protectors; and neutrons are detrimental to metal devices and especially to electrical appliances. Boron neutron capture therapy has been adopted as an effective therapy for glioblastoma/astrocytoma, but special considerations are required for anaesthesia.
Shinomura
T
T
Department of Anaesthesia, Kyoto University Hospital, Sakyo-ku, Kyoto 606-8507, Japan. shino@kuhp.kyoto-u.ac.jp
Furutani
H
H
Osawa
M
M
Ono
K
K
Fukuda
K
K
D000768:Anesthesia, General / Q000379:methods*; D016754:Boron Neutron Capture Therapy; D001932:Brain Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D003399:Craniotomy; D005909:Glioblastoma / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans