Palladium-catalyzed regioselective arylation of an electron-rich olefin by aryl halides in ionic liquids.
[figure: see text] Palladium-catalyzed arylation of the electron-rich olefin butyl vinyl ether has been accomplished in the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]), using as the arylating agents aryl iodides and bromides instead of the commonly used, but commercially unavailable and expensive, aryl triflates. The reaction proceeds with high efficiency and remarkable regioselectivity, leading almost exclusively to substitution by various aryl groups at the olefinic carbon alpha to the heteroatom of butyl vinyl ether.
Xu
L
L
Leverhulme Centre for Innovative Catalysis, Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, U.K.
Chen
W
W
Ross
J
J
Xiao
J
J