Brain energetics of cardiopulmonary cerebral resuscitation.
Recovery of normal brain energetic conditions during and after resuscitation from cardiac arrest is critical for survival and good neurologic outcome. This review emphasizes the glucose-driven metabolic processes during and after ischemia and on the post-resuscitation development of secondary energy derangements. It also explores some potential therapeutic interventions designed to attenuate these energy derangements. The article summarizes some bench research and is not intended to provide treatment strategies for clinical application.
Ebmeyer
U
U
University of Magdeburg, School of Medicine, Germany.
Katz
L M
LM
D001921:Brain / Q000098:blood supply / Q000378:metabolism / Q000503:physiopathology*; D016887:Cardiopulmonary Resuscitation; D004632:Emergency Medical Services; D004734:Energy Metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D010100:Oxygen / Q000378:metabolism; D012039:Regional Blood Flow
D005947:Glucose; D010100:Oxygen