ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12.
Microbes have developed a number of different strategies to utilize iron, which is a vital element for most organisms but not always readily available from the environment. Based on experimental studies and sequence analysis data, this article gives a short overview of ABC transporters related to iron uptake: components of three distinct families mediate the translocation of iron, siderophores, heme and vitamin B12 across the cytoplasmic membrane of bacteria.
Köster
W
W
Environmental Microbiology and Molecular Ecotoxicology (MIX), Swiss Federal Inst for Environmental Science and Technology (EAWAG), Dübendorf. wolfgang.koester@eawag.ch
D018528:ATP-Binding Cassette Transporters / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D017124:Conserved Sequence; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005290:Ferric Compounds / Q000378:metabolism; D006418:Heme / Q000378:metabolism*; D007291:Inosine Monophosphate / Q000378:metabolism; D007501:Iron / Q000378:metabolism*; D010802:Phylogeny; D017262:Siderophores / Q000378:metabolism*; D013379:Substrate Specificity; D014805:Vitamin B 12 / Q000378:metabolism*
D018528:ATP-Binding Cassette Transporters; D005290:Ferric Compounds; D017262:Siderophores; D007291:Inosine Monophosphate; D006418:Heme; D007501:Iron; D014805:Vitamin B 12