Bidentatoside I, a new triterpene saponin from Achyranthes bidentata.
Bidentatoside I (1) is a new triterpene saponin bearing an unusual dioxopropionic acid unit, isolated from the roots of Achyranthes bidentata. Structural elucidation was performed mainly by chemical and homo- and heteronuclear 2D NMR techniques. This compound did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.
Mitaine-Offer
A C
AC
Laboratoire de Pharmacognosie, Unité MIB, J E 2244, Faculté de Pharmacie, Université de Bourgogne, 7 Bd. Jeanne D'Arc, BP 87900, 21079 Dijon, France.
Marouf
A
A
Pizza
C
C
Khanh
T C
TC
Chauffert
B
B
Lacaille-Dubois
M A
MA
D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D003110:Colonic Neoplasms / Q000188:drug therapy; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D008956:Models, Chemical; D012503:Saponins / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D012503:Saponins; D014315:Triterpenes; C433584:bidentatoside I