[Effects of ionol, alpha-tocopherol and lipin on the processes of peroxidation in the syndrome of prolonged crush].
Experimental investigations of the influence of ionol and alpha-tokoferol in combined usage and liposomes on the processes of lipids peroxidation in the heart and blood at the cellular and subcellular level during crunch syndrome were made. The injection of ionol and alfa-tokoferol combined and lipid decreases the production of lipids peroxidation and increase antioxidation organism status and as a result the survival abilities of animals. These data, refected antioxidation provision of the heart and blood under crunh syndrome at the cellular and subcellular levers are given. Low antioxidation provision of the heart must be taken in consideration, that grounds the necessity of taking into account of the antioxidation cellular defence modulations factors under the complex therapy working out.
Iel'skyĭ
V M
VM
Donetsk Medical University, Ministry of Public Health of Ukraine.
Zavedeia
T L
TL
Bohatyr'ova
O V
OV
Kolesnikova
S V
SV
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D002084:Butylated Hydroxytoluene / Q000494:pharmacology*; D003444:Crush Syndrome / Q000188:drug therapy*; D004195:Disease Models, Animal; D004359:Drug Therapy, Combination; D015227:Lipid Peroxidation / Q000187:drug effects*; D009930:Organic Chemicals; D051381:Rats; D014810:Vitamin E / Q000494:pharmacology*
D000890:Anti-Infective Agents; D000975:Antioxidants; D009930:Organic Chemicals; C088310:lipine; D014810:Vitamin E; D002084:Butylated Hydroxytoluene