Atypical cilia in the bronchiolar epithelium of pigs experimentally infected with hog cholera virus.
To study the effect of hog cholera virus on the epithelial cells of the bronchiolar mucosa, 12 pigs were inoculated with a highly virulent strain. Immunohistochemical and ultrastructural examination of the ciliated epithelial cells demonstrated an increase in the number of atypical cilia. The latter showed alterations in the microtubular pattern, possibly resulting from viral interference with the normal metabolism of the epithelial cells.
Carrasco
L
L
Departamento de Anatomía y Anatomía Patológica Comparadas, Edificio de Sanidad Animal, Facultad de Veterinaria, Universidad de Córdoba, Campus Universitario de Rabanales, 14014 Córdoba, Spain.
Ruiz-Villamor
E
E
Gómez-Villamandos
J C
JC
Bautista
M J
MJ
Nuñez
A
A
Quezada
M
M
Sierra
M A
MA
D000818:Animals; D001980:Bronchi / Q000648:ultrastructure* / Q000821:virology; D002923:Cilia / Q000648:ultrastructure*; D006691:Classical Swine Fever / Q000473:pathology*; D006692:Classical Swine Fever Virus / Q000276:immunology / Q000502:physiology* / Q000648:ultrastructure; D004848:Epithelium / Q000648:ultrastructure / Q000821:virology; D005260:Female; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D020545:Respiratory Mucosa / Q000648:ultrastructure / Q000821:virology; D013552:Swine; D014759:Viral Envelope Proteins / Q000032:analysis; D014779:Virus Replication
D014759:Viral Envelope Proteins; C087086:glycoprotein E2, classical swine fever virus