title: Nitinol stent for the treatment of tracheobronchial stenosis.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the potential utility of implantation of a nickel-titanium alloy (nitinol) stent for the treatment of malignant or benign tracheobronchial stenosis.
  
  
  METHODS
  We evaluated 18 patients (14 men and 4 women) who received 24 nitinol stents, between November 1997 and May 2000. All 18 patients had severe dyspnea caused by tracheobronchial stenosis. The underlying condition was malignant disease in 15 patients, and benign tracheal collapse in the other 3 patients.
  
  
  RESULTS
  Implantation of the stent was successfully performed in all patients. Seventeen patients experienced immediate clinical improvement in respiratory symptoms. The remaining 1 patient with a bronchial fistule after lobectomy did not benefit, and died of pneumonia at 16 days after the implantation. In 15 patients, the procedure was performed using a flexible bronchoscope under local anesthesia alone, while the remaining 3 patients needed intravenous sedation. There was no complication resulting from the stent implantation. Among the 3 patients with benign tracheal collapse, 2 patients were alive at 746 and at 401 days after the stent implantation, at the time of this report. One patient with cicatricial stenosis after intubation died of heart failure due to previous myocardial infarction. Among the 15 patients with malignant disease, 4 patients have survived for 177 to 305 days to date, while the other 11 patients have died of primary malignancy with a mean survival duration of 60.2 days.
  
  
  CONCLUSIONS
  The nitinol stent was effective in treating malignant or benign tracheobronchial stenosis, and had some remarkable advantages compared with other tracheobronchial stents. In stenting, most procedures can be performed using flexible bronchoscope under local anesthesia.
authors: Department of Surgery I, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
authors: S
authors: S
authors: Sasano
authors: T
authors: T
authors: Onuki
authors: T
authors: T
authors: Adachi
authors: K
authors: K
authors: Oyama
authors: T
authors: T
authors: Ikeda
authors: M
authors: M
authors: Kanzaki
authors: H
authors: H
authors: Kuwata
authors: M
authors: M
authors: Sakuraba
authors: T
authors: T
authors: Matsumoto
authors: S
authors: S
authors: Nitta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys / Q000627:therapeutic use*; D000772:Anesthesia, Local; D001982:Bronchial Diseases / Q000628:therapy*; D001999:Bronchoscopy; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents; D014134:Tracheal Neoplasms / Q000150:complications; D014135:Tracheal Stenosis / Q000628:therapy*
chemical_list: D000497:Alloys; C013616:nitinol