The Yersinia high-pathogenicity island: an iron-uptake island.
Highly pathogenic Yersinia carry a pathogenicity island termed high-pathogenicity island (HPI). The Yersinia HPI comprises genes involved in the synthesis of the siderophore yersiniabactin and can thus be regarded as an iron-uptake island. A unique characteristic of the HPI is its wide distribution among different enterobacteria such as Escherichia coli, Klebsiella, Citrobacter and Salmonella. Other types of iron-uptake systems are also carried by different pathogenicity islands in enterobacteria.
Carniel
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Laboratoire des Yersinia, Unité des bactériologie moléculaire et médicale, Institut Pasteur, 28, rue du Dr. Roux, 75724 cedex 15, Paris, France. carniel2@pasteur.fr
D000818:Animals; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000235:genetics*; D004755:Enterobacteriaceae / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity; D019143:Evolution, Molecular; D005798:Genes, Bacterial; D006801:Humans; D007501:Iron / Q000378:metabolism*; D033862:Iron-Binding Proteins; D033902:Periplasmic Binding Proteins; D010636:Phenols; D017262:Siderophores / Q000235:genetics*; D013844:Thiazoles; D014774:Virulence / Q000235:genetics; D015007:Yersinia / Q000235:genetics* / Q000378:metabolism / Q000472:pathogenicity*; D015009:Yersinia Infections / Q000382:microbiology
D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D033862:Iron-Binding Proteins; D033902:Periplasmic Binding Proteins; D010636:Phenols; D017262:Siderophores; D013844:Thiazoles; C104398:yersiniabactin; D007501:Iron