title: Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis.
abstract: The SUC1/CKS1 proteins interact with cyclin-dependent kinases (CDKs) and play an essential, but yet not entirely resolved, role in the regulation of the cell cycle. With the Arabidopsis thaliana CKS1At protein as bait in a two-hybrid screen, two novel Arabidopsis CDKs, Arath;CDKB1;2 and Arath;CDKB2;1, were isolated. A closely related homologue of Arath;CDKB2;1 was discovered in the databases and was nominated Arath;CDKB2;2. Transcript analysis of the five known Arath;CDKA and Arath;CDKB genes revealed that they all had the highest expression in flowers and cell suspensions. Differences in the expression patterns in roots, leaves and stems suggest unique roles for each CDK.
authors: Vakgroep Moleculaire Genetica, Departement Plantengenetica, Vlaams Interuniversitair Instituut voor Biotechnologie, Universiteit Gent, KL Ledeganckstraat 35, B-9000 Gent, Belgium.
authors: V
authors: V
authors: Boudolf
authors: S
authors: S
authors: Rombauts
authors: M
authors: M
authors: Naudts
authors: D
authors: D
authors: Inzé
authors: L
authors: L
authors: De Veylder
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D017360:Arabidopsis / Q000201:enzymology*; D029681:Arabidopsis Proteins; D002453:Cell Cycle; D018797:Cell Cycle Proteins; D002478:Cells, Cultured; D018844:Cyclin-Dependent Kinases / Q000302:isolation & purification* / Q000378:metabolism; D005656:Fungal Proteins / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D008969:Molecular Sequence Data; D010940:Plant Proteins; D018547:Plant Stems / Q000201:enzymology; D029701:Saccharomyces cerevisiae Proteins
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D029681:Arabidopsis Proteins; C081185:CKS1 protein, S cerevisiae; D018797:Cell Cycle Proteins; D005656:Fungal Proteins; D010940:Plant Proteins; D029701:Saccharomyces cerevisiae Proteins; C435712:CDKB1;2 protein, Arabidopsis; C435713:CDKb2;2 protein, Arabidopsis; D018844:Cyclin-Dependent Kinases