Acanthamoeba polyphaga in rheumatoid arthritis: possibility for a chronic infection.
Acanthamoeba polyphaga (AP) is ubiquitous in nature and frequently infects humans. AP has some features, such as persistence, which makes it an attractive candidate in studies of a possible infectious aetiology in rheumatoid arthritis (RA). In this study the occurrence of AP-specific antibodies was compared between RA patients and matched controls.
Jeansson
S
S
Department of Microbiology, Ullevaal University Hospital, Oslo, Norway. stig.jeansson@ioks.uio.no
Kvien
T K
TK
D000048:Acanthamoeba / Q000276:immunology*; D000328:Adult; D000368:Aged; D000818:Animals; D000913:Antibodies, Protozoan / Q000096:biosynthesis*; D001172:Arthritis, Rheumatoid / Q000276:immunology* / Q000469:parasitology*; D002908:Chronic Disease; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007070:Immunoglobulin A / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D008297:Male; D008875:Middle Aged
D000913:Antibodies, Protozoan; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M