title: Epidemiology, symptoms and treatment of paragonimiasis in Sin Ho district, Lai Chau province, Vietnam.
abstract: Sin Ho is a district of the northern mountainous province of Lai Chau, Vietnam, where the people have the habit of eating undercooked crabs. A study on paragoniamiasis carried out from 1994 to 1995 with 1,642 persons in this endemic area, showed that the rate of eating raw-crab was 72.5%. Crab examination (Ranguna kimboiensis) showed an infection rate of Paragonimus metacercaria of 98.1%. With 624 stool samples examined by Kato technique, the infection rate of Paragonimus in humans was 6.4%. With 338 sputum samples examined by direct and centrifuge methods, the infection rate of Paragonimus was 7.4%. Most of the patients were children (63.2%). The infection rate of Paragonimus in dogs was 18.2 - 33.3%. Adult worms, collected from the dogs in the field and from the cats in laboratory, were identified as Paragonimus heterotremus. The main symptoms of Paragonimus patients were cough and hemoptysis (92%), discontinuously developed (96%), without fever (94%), chest pain (70%), pleural effusion (26%), neurogical symptoms (8%), eosinophilia (88.9%), nodular ring shadows in the lungs, as shown by chest X-ray examination and more in lower lobe, (76.2%). Paragonimiasis patients were treated by (a) Praziquantel 25 mg/kg/day x 3 days; the cure rate was 68.8%. (b) Praziquantel 50 mg/kg/day x 3 days; the cure rate was 75%.
authors: National Institute of Malariology, Parasitology and Entomology, Ha Noi, Vietnam.
authors: N V
authors: NV
authors: De
authors: L D
authors: LD
authors: Cong
authors: H
authors: H
authors: Kino
authors: D T
authors: DT
authors: Son
authors: H V
authors: HV
authors: Vien
mesh_terms: D000293:Adolescent; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D003386:Brachyura / Q000469:parasitology*; D002415:Cats / Q000469:parasitology; D002648:Child; D004285:Dogs / Q000469:parasitology; D005243:Feces / Q000469:parasitology; D006801:Humans; D010237:Paragonimiasis / Q000188:drug therapy* / Q000453:epidemiology* / Q000503:physiopathology / Q000662:veterinary; D010238:Paragonimus / Q000302:isolation & purification*; D011223:Praziquantel / Q000627:therapeutic use*; D012758:Shellfish / Q000469:parasitology*; D013552:Swine / Q000469:parasitology; D014744:Vietnam / Q000453:epidemiology
chemical_list: D000871:Anthelmintics; D011223:Praziquantel