title: Fatty acid composition of brown adipose tissue in genetically heat-tolerant FOK rats.
abstract: The phospholipid fatty acid composition of brown adipose tissue (BAT) was examined in inbred heat-tolerant FOK rats and compared with that in conventional Wistar rats not previously exposed to heat. The FOK rats showed higher unsaturation states, as indicated by higher levels of polyunsaturated fatty acids and a higher unsaturation index and polyunsaturated fatty acids/saturated fatty acids ratio. This higher level of unsaturation was characterized by the higher amount of polyunsaturated fatty acids such as linoleic acid, arachidonic acid and docosahexaenoic acid. It may be concluded that the increased docosahexaenoic acid level in BAT phospholipids brings about the hyperplasia of BAT, causing an enhancement of its in vivo thermogenic activity as well as the systemic non-shivering thermogenesis observed in heat-tolerant FOK rats.
authors: Hokkaido University of Education, Asahikawa 070-8621, Japan.
authors: T
authors: T
authors: Ohno
authors: F
authors: F
authors: Furuyama
authors: A
authors: A
authors: Kuroshima
mesh_terms: D002001:Adipose Tissue, Brown / Q000737:chemistry*; D000818:Animals; D001833:Body Temperature Regulation / Q000235:genetics / Q000502:physiology; D005227:Fatty Acids / Q000032:analysis*; D006358:Hot Temperature; D008297:Male; D008685:Meteorological Concepts; D010743:Phospholipids / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar
chemical_list: D005227:Fatty Acids; D010743:Phospholipids