Successful management of an ovarian enlargement resembling ovarian hyperstimulation in a premenopausal breast cancer patient receiving tamoxifen with cotreatment of GnRH-agonist.
Tamoxifen use in breast cancer patients may cause ovarian cysts. This report presents a case of complex cyst resembling ovarian hyperstimulation in a premenopausal breast cancer patient receiving tamoxifen which resolved by administering monthly depot GnRH-agonist (GnRH-a) without abandoning the tamoxifen treatment.
Turan
C
C
Department of Obstetrics and Gynecology, Kartal Research Hospital, Petrol-is Mah. Batman Sok. No. 11, D 14, Toprakyol-Kartal, 81410, Istanbul, Turkey.
Unal
O
O
Dansuk
R
R
Guzelmeric
K
K
Cengizoglu
B
B
Esim
E
E
D000328:Adult; D001943:Breast Neoplasms / Q000188:drug therapy*; D003692:Delayed-Action Preparations; D003937:Diagnosis, Differential; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D010048:Ovarian Cysts / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D016471:Ovarian Hyperstimulation Syndrome; D017697:Premenopause; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use; D014463:Ultrasonography
D003692:Delayed-Action Preparations; D013629:Tamoxifen; D007987:Gonadotropin-Releasing Hormone