(+)-Totarol from Chamaecyparis nootkatensis and activity against Mycobacterium tuberculosis.
The isolation of (+)-totarol as active compound against Mycobacterium tuberculosis is reported from Chamaecyparis nootkatensis outerbark.
Constantine
G H
GH
College of Pharmacy, Oregon State University, Corvallis, OR 97331, USA.
Karchesy
J J
JJ
Franzblau
S G
SG
LaFleur
L E
LE
D045784:Abietanes; D000995:Antitubercular Agents / Q000494:pharmacology*; D004224:Diterpenes / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology; D018547:Plant Stems; D010946:Plants, Medicinal; D014197:Trees
D045784:Abietanes; D000995:Antitubercular Agents; D004224:Diterpenes; D010936:Plant Extracts; C078548:totarol