title: Saliva cotinine as indicator of cigarette smoking in pregnant women.
abstract: OBJECTIVE
  To assess use of saliva cotinine as a quantitative objective index of smoking in pregnant women.
  
  
  METHODS
  National survey using quota sampling of pregnant women in England. Face-to-face interviews were conducted in the respondents' own homes.
  
  
  METHODS
  Respondents' homes.
  
  
  METHODS
  N = 1009 pregnant women, mean age = 27.9 years.
  
  
  METHODS
  Saliva cotinine and current smoking status.
  
  
  RESULTS
  Saliva cotinines revealed under-reporting among pregnant women by about 3%.
  
  
  CONCLUSIONS
  Pregnant women under-report current smoking status. The optimal cut-off point for validating smoking status among this group requires further research. The results also highlight the need for an improved understanding of the effects of pregnancy on the metabolism of nicotine.
authors: Heatlth Education Authority, London, UK. lesley.owen@hda-online.org.uk
authors: L
authors: L
authors: Owen
authors: A
authors: A
authors: McNeill
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis; D003367:Cotinine / Q000032:analysis*; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000378:metabolism*; D015995:Prevalence; D012463:Saliva / Q000737:chemistry*; D012907:Smoking / Q000453:epidemiology / Q000378:metabolism*; D000074606:Smoking Prevention
chemical_list: D015415:Biomarkers; D003367:Cotinine