Pneumonectomy for lung cancer in heart transplant recipient.
Prolonged nonspecific immunosuppression after solid-organ transplantation is associated with an increased risk of certain cancers. Review of the medical literature reveals that the combination of profound immunossuppression (triple-drug immunosuppression), a heavy smoking history, advanced age and a working exposition puts cardiac transplant recipients at increased risk for the development of aggressive lung cancer. These tumors in cardiac transplant recipients carry a poor prognosis. We present one case of bronchogenic carcinoma in a cardiac transplant patient. The patient was operated to resect the tumor and a long-term cure and a good quality of life should, however, be offered.
Strauch
J T
JT
Department of Thoracic and Cardiovascular Surgery, University Hospital of Göttingen, Germany. justus.strauch@med.uni-jena.de
Aleksic
I
I
Baryalei
M M
MM
Dalichau
H
H
D002294:Carcinoma, Squamous Cell / Q000139:chemically induced / Q000601:surgery*; D016027:Heart Transplantation / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008175:Lung Neoplasms / Q000139:chemically induced / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy
D007166:Immunosuppressive Agents