title: A retrospective study on the efficacy of short-term perioperative prophylaxis in abdominal surgery for hernia repair in 1,254 patients.
abstract: Between 1992 and 1999 1,254 patients requiring hernioplasty came to our Department of Surgery, at San Giovanni Valdarno Hospital, Arezzo. In 94% of cases a prosthetic device was inserted. All patients received a preoperative antibiotic prophylaxis with ceftriaxone, administered intravenously in a single 2 g dose, before surgery. We have retrospectively evaluated the incidence of postoperative infections in these patients: no surgical wound infection occurred, while we observed 10 cases of systemic infections, 5 respiratory tract infections and 5 urinary tract infections, all of which were successfully treated with antibiotics. Tolerability was good: no adverse reaction to ceftriaxone was observed. In this retrospective study ceftriaxone was shown to be effective in preventing the onset of postoperative infections.
authors: L
authors: L
authors: Gervino
authors: G
authors: G
authors: Cangioni
authors: F
authors: F
authors: Renzi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019072:Antibiotic Prophylaxis / Q000191:economics / Q000706:statistics & numerical data*; D002443:Ceftriaxone / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D059685:Herniorrhaphy; D006801:Humans; D015994:Incidence; D007262:Infusions, Intravenous; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000517:prevention & control*
chemical_list: D002443:Ceftriaxone