[Medullary carcinoma of the thyroid gland].
We report the experience of the Institute of Surgical Pathology of the University of Parma on three patients with sporadic medullary thyroid carcinoma (MTC). MTC is a tumor of parafollicolor cells origin (C cells). The surgical excision of the thyroid tumor and cervical node metastases is potentially curative. The other therapeutic options are limited. Considerable emphasis has been placed on early diagnosis and surgery for multiple endocrine neoplasia (MEN) related MTC. Genetic screening promises earlier and accurate diagnosis (RET gene mutations are found in MEN).
Del Rio
P
P
Istituto di Clinica Chirurgica Generale e dei Trapianti d'Organo Cattedra di Chirurgia Generale, Università degli Studi di Parma. pachi@unipr.it
Ferreri
G
G
Zannoni
M
M
Robuschi
G
G
Sianesi
M
M
D000328:Adult; D018276:Carcinoma, Medullary / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000601:surgery*