title: Increased accumulation of Tl-201 in monostotic Paget's disease of the patella: evaluation with quantitative analysis.
abstract: Monostotic Paget's disease of the patella was detected with Tc-99m MDP and Tl-201 scans. Diffuse intense uptake of MDP in the left patella was observed on the blood-pool and late phases of the bone scan. Tl-201 imaging was performed to differentiate a malignant process and showed diffuse marked accumulation at the same site. Semiquantitative analysis of the patella region on both Tc-99m MDP and Tl-201 scans did not support a diagnosis of cancer. Radiographs showed the features of Paget's disease of the bone. Findings of a pathologic evaluation were compatible with the diagnosis of osteitis deformans. This case represents the unusual skeletal involvement of monostotic Paget's disease of the bone in the patella. Tl-201 accumulation in the Paget's lesion was suggested to be caused by increased metabolic activity of the lesion but was not indicative of a malignant process.
authors: Department of Nuclear Medicine, Gazi University Faculty of Medicine, Beşevler, Ankara, Turkey. evrimaba@hotmail.com
authors: E
authors: E
authors: Abamor
authors: M T
authors: MT
authors: Kitapçi
authors: E
authors: E
authors: Cila
authors: N
authors: N
authors: Gökçora
authors: O
authors: O
authors: Uluoğlu
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010001:Osteitis Deformans / Q000000981:diagnostic imaging*; D010329:Patella / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D013794:Thallium Radioisotopes
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D013669:Technetium Tc 99m Medronate