title: Effectiveness of terbinafine in the eradication of Microsporum canis from laboratory cats.
abstract: In this study, the coats of 20 cats with no dermatophytosis lesions were sampled for colonization by Microsporum canis, which was isolated in 45% of cases. All cats were treated with oral terbinafine for 3 weeks. The drug was administered orally at a daily dosage 8.25 mg kg-1. Mycologic status was assessed at the end of the treatment; and after follow-up at 2 days, and 4 and 9 weeks. The final evaluation revealed a complete mycologic cure of all cats by obtaining negative cultures, thereby demonstrating that terbinafine is an effective method of eradication of dermatophyte colonization.
authors: Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, México D. F.
authors: L R
authors: LR
authors: Castañón-Olivares
authors: P
authors: P
authors: Manzano-Gayosso
authors: R
authors: R
authors: López-Martínez
authors: I A
authors: IA
authors: De la Rosa-Velázquez
authors: E
authors: E
authors: Soto-Reyes-Solís
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use*; D002415:Cats; D003881:Dermatomycoses / Q000188:drug therapy* / Q000382:microbiology / Q000635:transmission; D004195:Disease Models, Animal; D005260:Female; D005500:Follow-Up Studies; D008297:Male; D008864:Microsporum; D009281:Naphthalenes / Q000627:therapeutic use*; D000077291:Terbinafine
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine