title: Forced vital capacity in two large outpatient populations with chronic spinal cord injury.
abstract: OBJECTIVE
  To determine the expected vital capacity in persons with chronic spinal cord injury (SCI) in relation to injury level, completeness of injury, smoking and duration of injury, as an aid to diagnosis and management of respiratory complications.
  
  
  METHODS
  A New York City veterans' hospital and a Los Angeles public rehabilitation hospital.
  
  
  METHODS
  Case series from the two hospitals were pooled. Participants (adult outpatients with SCI of duration >1 year, not ventilator-dependent) were evaluated by conventional forced expiratory spirometry. Cross-sectional analysis was performed, using multiple regression, on the entire population and defined subgroups. The principal outcome measure was forced vital capacity (FVC).
  
  
  RESULTS
  In the subjects with complete-motor lesions, FVC ranged from near 100% of normal predicted values in the group with low paraplegia, to less than 50% in those with high tetraplegia. Incomplete lesions mitigated FVC loss in tetraplegia. In subjects with paraplegia, longer duration of injury was associated with greater loss, and smoking-related loss was evident at older but not at younger ages, presumably due to greater pack years in older subjects.
  
  
  CONCLUSIONS
  Vital capacity/SCI level relationships determined here may have diagnostic and prognostic value. Smoking-related FVC loss is important in persons with SCI as in others, although at higher levels it may be obscured by SCI-related loss.
authors: Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA.
authors: W S
authors: WS
authors: Linn
authors: A M
authors: AM
authors: Spungen
authors: H
authors: H
authors: Gong
authors: R H
authors: RH
authors: Adkins
authors: W A
authors: WA
authors: Bauman
authors: R L
authors: RL
authors: Waters
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D010264:Paraplegia; D011336:Probability; D011379:Prognosis; D011782:Quadriplegia; D012044:Regression Analysis; D012129:Respiratory Function Tests; D012140:Respiratory Tract Diseases / Q000175:diagnosis* / Q000209:etiology*; D012720:Severity of Illness Index; D013119:Spinal Cord Injuries / Q000150:complications*; D013147:Spirometry; D014797:Vital Capacity