title: [Efficacy of modified ultrafiltration in coronary artery bypass grafting].
abstract: We evaluated the efficacy of modified ultrafiltration (MUF) in coronary artery bypass grafting. Twenty patients were divide into two groups consisting of a control group (n = 11) and a MUF group (n = 9). MUF was carried out for fifteen minutes immediately after the completion of cardiopulmonary bypass. The blood flow through the ultrafilter was 300 ml/min and about 1,200 ml of water was removed. The hematocrit elevated significantly from 25% to 30% in the MUF group (p < 0.01). Postoperative blood loss in the first 24 hours in the MUF group was significantly less than that in the control group (8 +/- 2 ml/kg vs 12 +/- 4 ml/kg, p < 0.01). There was no statistical difference in the percentage of the increase in body weight after the operation, inflammatory reaction and pulmonary function (A-a DO2, PaO2/FIO2 and duration of intubation) between two groups. In conclusion, MUF is useful to hemoconcentrate and reduce postoperative blood loss in coronary artery bypass grafting.
authors: Department of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors: M
authors: M
authors: Kamada
authors: K
authors: K
authors: Niibori
authors: H
authors: H
authors: Akimoto
authors: H
authors: H
authors: Yokoyama
authors: M
authors: M
authors: Tofukuji
authors: A
authors: A
authors: Iguchi
authors: M
authors: M
authors: Ohmi
authors: K
authors: K
authors: Tabayashi
authors: S
authors: S
authors: Kikuchi
authors: T
authors: T
authors: Matsuura
mesh_terms: D000368:Aged; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D001026:Coronary Artery Bypass; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery; D006400:Hematocrit; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation