[Cytogenetic analysis of 19 renal cell tumors].
To further evaluate the role of cytogenetic analysis we studied 19 cases of renal neoplasms. Specific chromosomal aberrations have been demonstrated associated with different histologic types. Particularly, clear cell renal cancers were associated with deletions of the short arm of chromosome 3 and papillary renal cell cancers demonstrated multiple trisomies, and chromophobe cancers and oncocytomas were characterized by loss of whole chromosomes. The utility of cytogenetics as a tool to define the pathological spectrum of renal cell neoplasms is stressed.
Cerasoli
S
S
Servizio di Anatomia Patologica, Citodiagnostica e Citogenetica, Ospedale M. Bufalini, Viale Ghirotti 486, Cesena, FC.
Spada
F
F
Buda
R
R
Turci
A
A
Giangaspero
F
F
D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000235:genetics*; D002869:Chromosome Aberrations / Q000235:genetics; D003582:Cytogenetics; D005260:Female; D006801:Humans; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics*; D008297:Male; D008875:Middle Aged