title: Brief report: macrographia in high-functioning adults with autism spectrum disorder.
abstract: The initial description of Asperger syndrome commented on the poor handwriting and motor coordination difficulties of individuals with this condition. Early descriptions of autism do not remark upon such difficulties. Recent evidence, however, suggests that individuals with both conditions have a similar motor control impairment. Handwriting has not been formally assessed in this context. Our study compared handwriting size between individuals with autism spectrum disorder and age- and IQ-matched control subjects. Macrographia was observed among subjects with autism spectrum disorder which remained statistically significant when covaried with educational level. This finding may correlate with the anatomical abnormalities present in the cerebellum of individuals with autism spectrum disorder.
authors: Department of Neurology, Ohio State University Medical Center, 1654 Upham Drive, Columbus, Ohio 43210, USA. beversdorf.2@osu.edu
authors: D Q
authors: DQ
authors: Beversdorf
authors: J M
authors: JM
authors: Anderson
authors: S E
authors: SE
authors: Manning
authors: S L
authors: SL
authors: Anderson
authors: R E
authors: RE
authors: Nordgren
authors: G J
authors: GJ
authors: Felopulos
authors: M L
authors: ML
authors: Bauman
mesh_terms: D000293:Adolescent; D000328:Adult; D020817:Asperger Syndrome / Q000175:diagnosis*; D002531:Cerebellum / Q000002:abnormalities; D005260:Female; D006236:Handwriting; D006801:Humans; D007360:Intelligence; D008297:Male; D011596:Psychomotor Disorders / Q000175:diagnosis