Regulatory effects of Ribotim on functional activity of neutrophils and wound healing during experimental burn trauma.
We studied the effects of ribonucleic immunotropic preparation Ribotim obtained from the thymus on functional activity of peripheral blood neutrophils and wound healing after burn trauma. Immunotherapy normalized immunological parameters, attenuated demarcation inflammation in burn wound, and promoted epithelialization of the wound surface preserving skin structures.
Semochkin
S V
SV
Laboratory of Molecular Immunology, Institute of Physicochemical Medicine, Russian Ministry of Health, Moscow.
Bekman
E M
EM
Baranova
O A
OA
Arion
V Y
VY
D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D002056:Burns / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D009504:Neutrophils / Q000166:cytology / Q000187:drug effects*; D012313:RNA / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000737:chemistry; D014020:Tissue Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D014945:Wound Healing / Q000187:drug effects*
D000276:Adjuvants, Immunologic; D014020:Tissue Extracts; D012313:RNA