Interaction of Clostridium botulinum C2 toxin with lipid bilayer membranes and Vero cells: inhibition of channel function by chloroquine and related compounds in vitro and intoxification in vivo.
Bachmeyer
C
C
Lehrstuhl für Biotechnologie, Theodor-Boveri Institut (Biozentrum) der Universität Würzburg, D-97074 Würzburg, Germany.
Benz
R
R
Barth
H
H
Aktories
K
K
Gilbert
M
M
Popoff
M R
MR
D000634:Aminoquinolines / Q000494:pharmacology; D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D001905:Botulinum Toxins / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D002522:Chlorocebus aethiops; D002738:Chloroquine / Q000494:pharmacology*; D004347:Drug Interactions; D008051:Lipid Bilayers / Q000378:metabolism; D008567:Membranes, Artificial; D009994:Osmolar Concentration; D014709:Vero Cells / Q000187:drug effects* / Q000378:metabolism
D000634:Aminoquinolines; D000962:Antimalarials; D008051:Lipid Bilayers; D008567:Membranes, Artificial; D002738:Chloroquine; D001905:Botulinum Toxins; C096324:botulinum toxin type C; C001920:4-aminoquinoline