title: MMR vaccine in HIV-infected children -- potential hazards?
abstract: Although given routinely as prophylaxis against wild-type measles to HIV-infected children, the live attenuated measles component of the MMR triple vaccine also possesses potential for disease. We document a case of measles proven to be caused by vaccine strain in a HIV-infected child here in the UK and discuss the clinical and immunological aspects. We also consider the new guidelines for MMR vaccination in HIV-infected children adopted last year in the USA.
authors: Imperial College School of Medicine at St. Mary's, Norfolk Place, London W2 1PG, UK. p.goon@ic.ac.uk
authors: P
authors: P
authors: Goon
authors: B
authors: B
authors: Cohen
authors: L
authors: L
authors: Jin
authors: R
authors: R
authors: Watkins
authors: G
authors: G
authors: Tudor-Williams
mesh_terms: D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D002648:Child; D000075202:Contraindications; D015658:HIV Infections / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007223:Infant; D008297:Male; D008457:Measles / Q000209:etiology; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D017410:Practice Guidelines as Topic; D006113:United Kingdom; D014481:United States
chemical_list: D022542:Measles-Mumps-Rubella Vaccine