Synthesis and biological evaluation of pseudostellarin B.
A new potent bioactive cyclic peptide pseudostellarin B has been synthesised. The structure was elucidated by elemental analyses, IR, 1H NMR, 13C NMR and FAB mass spectral data. The synthesised compound was also screened for its antibacterial, antifungal, antiinflammatory and anthelmintic activities.
Poojary
B
B
Department of Post-Graduate Studies and Research in Chemistry, Mangalore University, Mangalagangothri, India.
Kumar
K H
KH
Belagali
S L
SL
D000818:Animals; D000871:Anthelmintics / Q000138:chemical synthesis / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000494:pharmacology*; D051381:Rats; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared
D000871:Anthelmintics; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000935:Antifungal Agents; D007202:Indicators and Reagents; D010456:Peptides, Cyclic; C439330:pseudostellarin B