title: A benzodiazepine mood effect scale: reliability and validity determined for alcohol-dependent subjects and adults with a parental history of alcoholism.
abstract: The Tufts Addiction Research Center Inventory--Morphine Benzedrine Group (ARCI-MBG) scale was designed to measure benzodiazepine-induced mood elevation. The reliability and validity of the Tufts ARCI-MBG scale were determined in 64 subjects with a history of alcoholism (HA), a positive history of parental alcoholism, defined as one or both parents meeting DSM-III-R criteria for alcohol dependence (PHP), and matched control subjects. Significant correlations were found for within-day Tufts ARCI-MBG scale scores for all groups and for between-day scores for PHP and matched control subjects. Interitem reliability was significant for pooled baseline scores. For HA subjects, correlations between mean Tufts ARCI-MBG scale and Drug Liking scores that were obtained after either alprazolam or diazepam administration were significant. These results suggest that the Tufts ARCI-MBG scale is a reliable test that is a valid measure of benzodiazepine-induced mood elevation.
authors: Division of Psychiatry, Boston University School of Medicine, MA 02118, USA.
authors: D A
authors: DA
authors: Ciraulo
authors: C M
authors: CM
authors: Knapp
authors: J
authors: J
authors: LoCastro
authors: D J
authors: DJ
authors: Greenblatt
authors: R I
authors: RI
authors: Shader
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects*; D000437:Alcoholism / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D001569:Benzodiazepines / Q000009:adverse effects*; D002648:Child; D016241:Child of Impaired Parents; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D015203:Reproducibility of Results; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000523:psychology*; D011795:Surveys and Questionnaires
chemical_list: D001569:Benzodiazepines