title: The use of a modified technique to reduce radioactive air contamination in aerosol lung ventilation imaging.
abstract: The aim of this study was to reduce airborne contamination resulting from the use of aerosols in lung ventilation scintigraphy. Lung ventilation imaging is frequently performed with 99mTc-diethylenetriaminepentaacetate aerosol (DTPA), derived from a commercial nebuliser. Airborne contamination is a significant problem with this procedure; it results in exposure of staff to radiation and can reduce gamma camera performance when the ventilation is performed in the camera room. We examined the level of airborne contamination resulting from the standard technique with one of the most popular nebuliser kits and tested a modification which significantly reduced airborne contamination. Air contamination was measured while ventilating 122 patients. The modified technique reduced air contamination by a mean value of 64% (p = 0.028) compared with the standard control technique. Additionally, differences in contamination were examined when a mask or mouthpiece was used as well as differences between operators. A simplified method of monitoring air contamination is presented using a commonly available surface contamination monitor. The index so derived was proportional to air contamination (r = 0.88). The problems and regulations associated with airborne contamination are discussed.
authors: Medical Physics Department, Bradford Royal Infirmary, UK. mikea@dhirst.demon.co.uk
authors: M
authors: M
authors: Avison
authors: G
authors: G
authors: Hart
mesh_terms: D000336:Aerosols; D000398:Air Pollution, Radioactive / Q000032:analysis / Q000517:prevention & control*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D009330:Nebulizers and Vaporizers; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000032:analysis*; D016284:Technetium Tc 99m Pentetate / Q000032:analysis*; D014692:Ventilation-Perfusion Ratio
chemical_list: D000336:Aerosols; D019275:Radiopharmaceuticals; D016284:Technetium Tc 99m Pentetate