Primary adenocarcinoma of the arytenoid: an ultrastructural study.
Primary adenocarcinoma of the larynx is a rare neoplasm that tends to spread to both regional lymph nodes and distant sites. A case of primary adenocarcinoma of the arytenoid in a 74-year-old man is presented. The tumor was evaluated by light and electron microscopy. A high percentage of intranuclear pseudoinclusions (more than 20% of the neoplastic cells) was a peculiar characteristic of the tumor. To the best of our knowledge, such a feature has not been reported previously and should be considered a hallmark of more aggressive behavior.
Torre
V
V
Institute of Ultrastructural Pathology, University of Messina, Italy.
Bucolo
S
S
Abbate
G
G
Albiero
F
F
Cicciarello
R
R
Cavallari
V
V
D000230:Adenocarcinoma / Q000532:radiotherapy / Q000648:ultrastructure*; D000368:Aged; D001193:Arytenoid Cartilage / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000648:ultrastructure; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D007822:Laryngeal Neoplasms / Q000532:radiotherapy / Q000648:ultrastructure*; D007828:Laryngoscopy; D008279:Magnetic Resonance Imaging; D008297:Male; D010166:Palliative Care