title: Idiopathic polymyositis and glomerulonephritis.
abstract: We report a 28-year-old male who presented with a clinical picture compatible with idiopathic polymyositis and nephrotic-range proteinuria. Muscle biopsy confirmed the diagnosis of polymyositis and a diagnostic renal biopsy demonstrated IgM mesangial glomerulonephritis. Following a short-course of prednisone, both the myositis and proteinuria resolved. Glomerulonephritis associated with idiopathic polymyositis is rare; however, since it appeared to respond to corticosteroid therapy concomitant with the improvement in the myositis, it was likely an associated immunological complication.
authors: Division of Nephrology and Hypertension, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.
authors: O F
authors: OF
authors: Valenzuela
authors: I W
authors: IW
authors: Reiser
authors: J G
authors: JG
authors: Porush
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D005500:Follow-Up Studies; D005921:Glomerulonephritis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007677:Kidney Function Tests; D008297:Male; D008853:Microscopy; D017285:Polymyositis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D011241:Prednisone / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D011241:Prednisone