Bacterial pathogenesis: the answer to virulence is in the pore.
A wide variety of Gram-negative bacterial pathogens use a 'type III' protein secretion system to deliver bacterial virulence factors into host cells. Recent results suggest that Gram-positive pathogens may employ similar methods to deliver virulence factors into host cells.
Gauthier
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Biotechnology Laboratory and Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3.
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D001422:Bacterial Adhesion; D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism; D001426:Bacterial Proteins / Q000378:metabolism; D003603:Cytotoxins / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000378:metabolism / Q000472:pathogenicity*; D006094:Gram-Positive Bacteria / Q000378:metabolism / Q000472:pathogenicity*; D010944:Plants / Q000382:microbiology*; D021381:Protein Transport; D014774:Virulence
D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D003603:Cytotoxins