Toward the creation of NMR databases in chiral solvents for assignments of relative and absolute stereochemistry: NMR desymmetrization of meso compounds.
[structure: see text] Examples of (13)C NMR desymmetrization of meso compounds are presented. On analysis of the NMR profiles of 1,3-diols, the additivity is recognized to predict the NMR profiles of 1,3,5-tirols.
Kobayashi
Y
Y
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Hayashi
N
N
Kishi
Y
Y
D000438:Alcohols / Q000737:chemistry*; D001596:Benzylamines / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D016208:Databases, Factual; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012997:Solvents; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000438:Alcohols; D001596:Benzylamines; D012997:Solvents; C045966:N-benzyl-N,N-dimethylamine