Hypersomnia due to acute disseminated encephalomyelitis in a 5-year-old girl.
A 5-year-old girl suffering from hypersomnia due to acute disseminated encephalomyelitis (ADEM) is reported. Brain CT revealed a large low-density lesion involving the lentiform nucleus, posterior limb of the internal capsule, thalamus, posterior hypothalamus and midbrain in the left side. She was treated with intravenous dexamethazone. After the initial dose of dexamethazone, hypersomnia was dramatically and rapidly improved. A later brain CT study disclosed that the lesion in the brain disappeared. The brain lesion in this case involved the waking center in the brain, which was described by Von Economo. We concluded that hypersomnia in this case was due to ADEM involving the neural mechanism for maintaing wakefulness, probably in the thalamus and posterior hypothalamus. Repeat all night polysomnograpy in this case disclosed prolonged total sleep time and increased amount of stage 3-4 sleep in the hypersomniac state.
Kanbayashi
T
T
Department of Pediatrics, Akita University School of Medicine, 1-1-1 Hondo, 010-8345, Akita, Japan
Goto
A
A
Hishikawa
Y
Y
Takahashi
Y
Y
Saito
Y
Y
Ogawa
Y
Y
Sugawara
J
J
Takada
G
G
Shimizu
T
T