[Clinical course of cytomegalovirus retinitis with the different antiretroviral therapies in our hospital].
OBJECTIVE
A study of protease inhibitors on CMV retinitis in HIV infected hospital patients.


METHODS
A retrospective study was performed in 485 diagnosed of AIDS, between January, 1990 and December 1998. Among those, 81 patients who were diagnosed of CMV retinitis, the following was studied: anti-retroviral treatment, anti CMV treatment, survival time and CD4 lymphocyte count.


RESULTS
Treatment with protease inhibitors in HIV patients showed an increase in life expectancy, reduced the incidence of CMV retinitis and a reduction in CMV retinitis prevention treatment was observed.


CONCLUSIONS
Treatment with protease inhibitors has reduced the rate of CMV retinitis in HIV patients.
Moreno Ruiz
O
O
Hospital Universitario Miguel Servet, Zaragoza.
Ferrer Novella
E
E
Torrón Fernández
C
C
Arazo Garcés
P
P
Melcon Sánchez
B
B
Honrubia López
F M
FM
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000401:mortality; D000998:Antiviral Agents / Q000627:therapeutic use*; D017726:Cytomegalovirus Retinitis / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D011480:Protease Inhibitors / Q000627:therapeutic use*; D012189:Retrospective Studies; D015996:Survival Rate
D000998:Antiviral Agents; D011480:Protease Inhibitors