Bioequivalent or nonbioequivalent?
The current tests for bioequivalence are based on assumptions that are not valid in general; this paper shows why it is necessary to use a method that does not depend upon assumptions that cannot, and need not, be proved in general.
Rescigno
A
A
Stillwater, MN 55082-9278, USA
Powers
J
J
Herderick
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EE
D019540:Area Under Curve; D017408:Guidelines as Topic; D006801:Humans; D010599:Pharmacokinetics; D013810:Therapeutic Equivalency; D013997:Time Factors; D014481:United States; D014486:United States Food and Drug Administration