title: Factors useful in predicting the success of oocyte donation: a 3-year retrospective analysis.
abstract: OBJECTIVE
  To establish prognostic relevance of parameters assessed in oocyte donation cycles.
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  Large university-based donor oocyte program.
  
  
  METHODS
  All oocyte recipient cycles achieving embryo transfer from September 1995 to October 1998.
  
  
  METHODS
  None.
  
  
  METHODS
  Pregnancy.
  
  
  RESULTS
  Recipient age and reproductive status, day 9 and 12 serum estradiol (E(2)) levels and a progesterone (P) level obtained 2 days after initiation of hormonal therapy did not correlate with pregnancy. Endometrial thickness, but not endometrial pattern, was useful in predicting pregnancy outcome. The clinical pregnancy and live-birth rate in cycles where the endometrial thickness was less than 8 mm was significantly lower when compared to cycles with an endometrial thickness > or =9 mm. Cycles where optimal quality embryos were transferred had the highest implantation (36%), clinical pregnancy (63%) and live birth (54%) rates and these rates were significantly higher than those of cycles where only poor quality embryos were available for transfer (10% implantation, 17% clinical pregnancy, and 8% live birth rates, respectively; P<.05).
  
  
  CONCLUSIONS
  The most reliable predictive factors for pregnancy in oocyte donation cycles are the quality of the embryos transferred and the recipient's mid-cycle endometrial thickness. Recipient monitoring should minimally include ultrasound assessment of endometrial thickness.
authors: Program for IVF, Reproductive Surgery and Infertility, Department of Obstetrics and Gynecology, New York University Medical Center, New York, New York, USA. nnoyes01@aol.com
authors: N
authors: N
authors: Noyes
authors: B S
authors: BS
authors: Hampton
authors: A
authors: A
authors: Berkeley
authors: F
authors: F
authors: Licciardi
authors: J
authors: J
authors: Grifo
authors: L
authors: L
authors: Krey
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000502:physiology; D004717:Endometrium / Q000000981:diagnostic imaging; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology; D008875:Middle Aged; D018587:Oocyte Donation; D011237:Predictive Value of Tests; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors; D014463:Ultrasonography
chemical_list: D011374:Progesterone; D004958:Estradiol