yMGV: a database for visualization and data mining of published genome-wide yeast expression data.
The yeast Microarray Global Viewer (yMGV) is an on-line database providing a synthetic view of the transcriptional expression profiles of Saccharomyces cerevisiae genes in most of the published expression datasets. yMGV displays a one-screen graphical representation of gene expression variations for each published genome-wide experiment, allowing quick retrieval of experimental conditions affecting expression of this gene. yMGV also provides tools to isolate groups of genes sharing similar transcription profiles in a defined subset of experiments. Additionally, yMGV furnishes a set of statistical tools for critical assessment of published data. We therefore believe that yMGV is an efficient tool that affords a quick and comprehensive overview of microarray data and generates new gene classifications. As of 20 March 2001 the yMGV database contains 6 000 000 measurements, representing genome-wide expression comparisons of 932 experiments from 39 microarray publications. The yMGV interface is available at http://transcriptome.ens.fr/ymgv/.
Marc
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P
Laboratoire de Génétique Moléculaire, CNRS 8541, Ecole Normale Supérieure, 46 Rue d'Ulm, 75005 Paris, France. pmarc@biologie.ens.fr
Devaux
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F
Jacq
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C
D019295:Computational Biology / Q000379:methods / Q000639:trends; D019992:Databases as Topic / Q000639:trends; D015870:Gene Expression; D020869:Gene Expression Profiling; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal / Q000235:genetics; D016681:Genome, Fungal; D020407:Internet; D020411:Oligonucleotide Array Sequence Analysis; D012331:RNA, Fungal / Q000032:analysis / Q000235:genetics; D012107:Research Design; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D013223:Statistics as Topic; D014158:Transcription, Genetic; D014584:User-Computer Interface
D012331:RNA, Fungal