[Prevalence of cannabis and tobacco use in patients attending a methadone center. Evaluation by urinary biomarkers].
OBJECTIVE
The aim of this study was to determine the prevalence of cannabis and tobacco use in a population attending a Methadone Center.


METHODS
We studied 49 patients over a 3-month period. Urine samples were obtained at three different times from each patient for analysis. We measured urinary cannabinoids using an immunopolarization assay to identify cannabinoid use. Cotinine concentrations were quantified in urine using a colorimetric assay to assess total urinary nicotine metabolites.


RESULTS
The prevalence of cannabis use was high in this population. Urinary cannabinoids were present in 63% of the samples. Similarly 90% had high-urinary cotinine concentrations.


CONCLUSIONS
Measurement of urinary biomarkers showed that tobacco and cannabis use was high among patients attending a Methadone Center.
Asnafi-Farhang
S
S
Service de Pharmacie, Hôpital Albert-Chenevier, 40, avenue Mesly, 94010 Créteil.
Hatchuel
P
P
Bourhis
F
F
Diviné
C
C
Lagrue
G
G
D000328:Adult; D015415:Biomarkers / Q000652:urine; D003124:Colorimetry; D015897:Comorbidity; D003367:Cotinine / Q000652:urine; D003863:Depression / Q000150:complications; D005260:Female; D016231:Fluorescence Polarization Immunoassay; D005602:France / Q000453:epidemiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D002189:Marijuana Abuse / Q000150:complications / Q000453:epidemiology* / Q000652:urine*; D009293:Opioid-Related Disorders / Q000150:complications* / Q000188:drug therapy*; D011159:Population Surveillance; D015995:Prevalence; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology* / Q000652:urine*; D015813:Substance Abuse Detection / Q000379:methods*; D016320:Substance Abuse Treatment Centers / Q000706:statistics & numerical data*; D013997:Time Factors
D015415:Biomarkers; D003367:Cotinine