[Insulin secretion and insulin sensitivity in relation to glucose tolerance in a group of subjects at a high risk for type 2 diabetes mellitus].
BACKGROUND
Oral glucose tolerance test was evaluated, as well as, insulin sensitivity/secretion in a group of subjects at risk for type 2 diabetes mellitus.


METHODS
Metabolic profile of subjects included in the new category, impaired fasting glucose (IFG), was also evaluated.


RESULTS
IFG and impaired glucose tolerance identify different alterations in glucose homeostasis.


CONCLUSIONS
Those subjects with IFG are heterogeneous in their oral glucose tolerance. They display defects not only in insulin sensitivity but also in their capacity to compensate for it.
Conget
I
I
Endocrinología y Diabetes Hospital Clínic i Universitari. Barcelona. iconget@clinic.ub.es
Fernández Real
J M
JM
Costa A
Casamitjana
R
R
Ricart
W
W
D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D008297:Male; D012307:Risk Factors
D007328:Insulin