Electrophoretic Properties of Latex Particles with Immobilized Bovine Serum Albumin.
In this study, bovine serum albumin (BSA) was covalently immobilized onto the surfaces of methyl methacrylate/methyl acrylic acid core-shell latex particles by the carbodiimide method, and the variation of the zeta potential of the BSA-latex complex as a function of the amount of BSA immobilized was measured. The experimental data revealed that the absolute zeta potential of BSA-latex complex exhibited a local minimum at 0.05 mg/m(2) of immobilized BSA. A two-layer model for the description of the electrophoretic behavior of the BSA-latex complex is proposed which is capable of explaining the behavior of the variation of the zeta potential as a function of the amount of BSA immobilized. Copyright 2001 Academic Press.
Young
Tai-Horng
TH
Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan, 10016, Republic of China
Kao
Chen-Yuan
CY
Hsieh
Meng-Ying
MY
Wang
Bing-Jie
BJ
Hsu
Jyh-Ping
JP