[Polymorphism of the angiotensin-converting enzyme gene in patients with coronary heart disease from Moscow population].
The insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene was studied in patients with coronary heart disease (CHD) and healthy individuals randomly sampled from the Moscow population. The ACE gene proved to be associated with the plasma apolipoprotein B (ApoB) content in CHD patients, but not associated with HCD development in individuals with elevated serum cholesterol and triglycerides. An association was not revealed between the alleles of the ACE gene and hypertension in CHD patients.
Shadrina
M I
MI
Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182 Russia.
Slominskiĭ
P A
PA
Miloserdova
O V
OV
Perova
N V
NV
Limborskaia
S A
SA
D000328:Adult; D000483:Alleles; D006801:Humans; D006973:Hypertension / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009031:Moscow; D017202:Myocardial Ischemia / Q000235:genetics*; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D011110:Polymorphism, Genetic; D012307:Risk Factors
D007703:Peptidyl-Dipeptidase A