title: [HELLP Syndrome as an indication for liver transplantation].
abstract: Liver rupture followed by multiorgan failure is perhaps the most catastrophic complication of the HELLP syndrome (hemolysis, elevated liver function, low platelets). Specific treatment options are currently limited and not routinely clarified. Here, we present a patient successfully managed by an innovative surgical approach consisting of combined total hepatectomy, portacaval shunt, and liver transplantation. A 26-year-old primipara (39th week of gestation) who suffered liver rupture as a complication of HELLP syndrome after delivery underwent a portacaval shunt after total hepatectomy. This combination was sufficient until the patient underwent orthotopic liver transplantation. The patient was discharged from the hospital after a dramatic recovery. Bridging portacaval shunt and consecutive orthotopic liver transplantation represented an effective therapy for this patient and should be considered early as a treatment option in patients with liver rupture complicating severe HELLP syndrome.
authors: Klinik für Allgemeine und Viszerale Chirurgie, Friedrich-Schiller-Universität, Jena, Deutschland. Hommann@bach.med.uni-jena.de
authors: M
authors: M
authors: Hommann
authors: U
authors: U
authors: Schotte
authors: K K
authors: KK
authors: Richter
authors: U
authors: U
authors: Möller
authors: R
authors: R
authors: Basciani
authors: J
authors: J
authors: Scheele
mesh_terms: D000328:Adult; D005260:Female; D017359:HELLP Syndrome / Q000000981:diagnostic imaging / Q000601:surgery*; D006498:Hepatectomy; D006801:Humans; D008107:Liver Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D016031:Liver Transplantation; D009102:Multiple Organ Failure / Q000000981:diagnostic imaging / Q000601:surgery; D011167:Portacaval Shunt, Surgical; D011247:Pregnancy; D012422:Rupture, Spontaneous; D014057:Tomography, X-Ray Computed