Dehydroepiandrosterone replacement in addison's disease.
Addison's disease is a rare endocrine disorder which can be life-threatening. It can also interfere with the normal development of adrenarche, resulting in the absence of pubic and axillary hair growth. We report a case of satisfactory restoration of adrenarche through DHEA administered in conjunction with the standard glucocortisone and fluorocortisone replacement.
Kim
S S
SS
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98105, USA. medssk@u.washington.edu
Brody
K H
KH
D000224:Addison Disease / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D000311:Adrenal Glands / Q000254:growth & development; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D001365:Axilla; D001786:Blood Glucose / Q000032:analysis; D003348:Cortisone / Q000627:therapeutic use; D003687:Dehydroepiandrosterone / Q000627:therapeutic use*; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood; D005260:Female; D005836:Genitalia, Female; D006197:Hair / Q000254:growth & development; D020249:Hormone Replacement Therapy; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000627:therapeutic use; D012880:Skin Pigmentation; D013739:Testosterone / Q000097:blood
D001786:Blood Glucose; D013739:Testosterone; D003687:Dehydroepiandrosterone; D019314:Dehydroepiandrosterone Sulfate; D000324:Adrenocorticotropic Hormone; D003348:Cortisone; D006854:Hydrocortisone