Some reactions with ketene dithioacetals part I: synthesis of antimicrobial pyrazol.
Pyrazolo[1,5-a]pyrimidines were synthesized via the reaction of ketene dithioacetals and 5-aminopyrazoles. The antibacterial and antifungal activities of some selected compounds are also reported.
Zaharan
M A
MA
Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.
El-Sharief
A M
AM
El-Gaby
M S
MS
Ammar
Y A
YA
El-Said
U H
UH
D000080:Acetals / Q000737:chemistry; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared
D000080:Acetals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D007202:Indicators and Reagents; D011720:Pyrazoles; D011743:Pyrimidines