title: The role of endoscopic retrograde pancreatography in the treatment of traumatic pancreatic duct injury.
abstract: BACKGROUND
  The status of the main pancreatic duct (MPD) is the most important determinant of the morbidity and mortality associated with pancreatic trauma. Early diagnosis and optimal treatment are critical, especially when there is MPD injury.
  
  
  METHODS
  Twenty-three patients with pancreatic trauma were studied prospectively with respect to clinical and laboratory findings, CT, and endoscopic retrograde pancreatography (ERP). Treatment modalities and clinical outcome were assessed in relation to ERP findings.
  
  
  RESULTS
  The pancreatic duct was injured in 14 of 23 patients (11 MPD, 3 branch duct). Contrast leakage from the MPD into peritoneal cavity at ERP confirmed MPD injury in 8 patients, who underwent surgical exploration. Three patients with leakage from a branch duct into the pancreatic parenchyma recovered with conservative treatment. Three patients in whom ERP demonstrated contrast leakage from the MPD confined to the parenchyma underwent successful transpapillary stent insertion with complete resolution of the leak at 3-month follow-up. Patients who underwent ERP more than 72 hours after trauma had a significantly higher rate of pancreas-associated complications and a tendency to remain hospitalized longer than patients who underwent ERP earlier.
  
  
  CONCLUSIONS
  Early ERP is one of the most useful methods for demonstrating MPD injury. ERP assists with treatment planning based on the degree of pancreatic duct injury.
authors: Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
authors: H S
authors: HS
authors: Kim
authors: D K
authors: DK
authors: Lee
authors: I W
authors: IW
authors: Kim
authors: S K
authors: SK
authors: Baik
authors: S O
authors: SO
authors: Kwon
authors: J W
authors: JW
authors: Park
authors: N C
authors: NC
authors: Cho
authors: B S
authors: BS
authors: Rhoe
mesh_terms: D000007:Abdominal Injuries / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000681:Amylases / Q000097:blood; D002648:Child; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003937:Diagnosis, Differential; D004322:Drainage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010183:Pancreatic Ducts / Q000000981:diagnostic imaging / Q000293:injuries* / Q000601:surgery; D011446:Prospective Studies; D015607:Stents; D015996:Survival Rate
chemical_list: D000681:Amylases