Acute idiopathic blind spot enlargement syndrome: prolonged retinal dysfunction revealed by multifocal electroretinogram technique.
OBJECTIVE
To report the multifocal electroretinographic findings of a patient with acute idiopathic blind spot enlargement syndrome recorded at 2 weeks and 4 months after the onset.


METHODS
A 35-year-old patient underwent static visual field (Humphrey, 30-2) and multifocal electroretinogram testing at 2 weeks and 4 months after the onset of acute idiopathic blind spot enlargement. The stimulus array for the multifocal electroretinogram consisted of 61 hexagons, and the total recording time was about 4 minutes.


RESULTS
At 2 weeks, the patient had a large, well-demarcated scotoma centered on the blind spot, and its margin extended to within 5 degrees of fixation. The multifocal electroretinograms were depressed in the areas corresponding to the scotoma. At 4 months, her visual symptoms disappeared and static visual fields showed normal sensitivities at almost all locations. However, the multifocal electroretinograms still revealed reduced focal responses in a broad area around the blind spot.


CONCLUSIONS
These results suggest that multifocal electroretinograms may be used to detect subclinical retinal dysfunction in patients with acute idiopathic blind spot enlargement.
Kondo
N
N
Department of Ophthalmology, Nagoya University School of Medicine, Nagoya, Japan. kondomi@med.nagoya-u.ac.jp
Kondo
M
M
Miyake
Y
Y
D000208:Acute Disease; D000328:Adult; D004596:Electroretinography / Q000379:methods; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D006984:Hypertrophy; D009898:Optic Disk / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis* / Q000503:physiopathology; D012607:Scotoma / Q000175:diagnosis* / Q000503:physiopathology; D013577:Syndrome; D014792:Visual Acuity; D014794:Visual Fields