title: Real-time I-MR-imaging--guided cryoablation of uterine fibroids.
abstract: In an ongoing prospective clinical trial, two patients with large, symptomatic uterine fibroids were treated with percutaneous magnetic resonance (MR)-imaging--guided cryoablation. Patients were followed with serial MR imaging studies and clinical evaluation according to Institutional Review Board protocol. Short-term imaging and clinical data were collected to assess the effects of the therapy. Both patients confirmed a significant reduction or elimination of their symptoms at 2 weeks after cryoablation. Measurements obtained from MR imaging performed after cryoablation documented a 65% and 53% reduction in each patient's fibroid volume at 8 weeks. Early clinical and imaging results confirm MR-imaging--guided cryoablation was effective at reducing or relieving these two patients' symptoms related to uterine fibroids and post-cryoablation imaging confirmed a significant reduction in fibroid volume.
authors: Department of Radiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi 39216-4504, USA.
authors: P E
authors: PE
authors: Sewell
authors: R M
authors: RM
authors: Arriola
authors: L
authors: L
authors: Robinette
authors: B D
authors: BD
authors: Cowan
mesh_terms: D003452:Cryosurgery / Q000379:methods*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000175:diagnosis / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000601:surgery*