title: Platelet apheresis for digital gangrene due to thrombocytosis in chronic myeloid leukaemia.
abstract: Thrombocytosis is a frequent presenting feature of myeloproliferate disorders and is associated with increased incidence of thrombotic and haemorrhage complications. However, these complications are rare in chronic myeloid leukaemia (CML). We describe a case of CML which presented with digital gangrene due to thrombocytosis. Reduction of the platelet count by plateletpheresis lead to rapid symptomatic relief and recovery from the gangrene.
authors: National Blood Service - South London Centre, UK. Nay.Win@nbs.nhs.uk
authors: N
authors: N
authors: Win
authors: D C
authors: DC
authors: Mitchell
mesh_terms: D000328:Adult; D005734:Gangrene / Q000209:etiology / Q000628:therapy*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000473:pathology; D008297:Male; D010976:Platelet Count; D010983:Plateletpheresis; D013922:Thrombocytosis / Q000150:complications* / Q000209:etiology; D014034:Toes / Q000473:pathology