title: [Usefulness of time-resolved projection MRA on evaluation of hemodynamics in cerebral occlusive diseases].
abstract: The usefulness for evaluation of cerebral hemodynamics using time-resolved projection MRA was studied in normal volunteers and patients of cerebrovascular diseases. Six normal volunteers and ten patients with cerebrovascular occlusive diseases including 6 of IC occlusion and 4 of post EC/IC bypass surgery underwent time-resolved projection MRA on a 1.5 T clinical MRI system. Projection angiograms are acquired with 2 D-fast SPGR sequence with a time resolution of approximately one image per second, 40 images being acquired consecutively before and after bolus injection Gd-DTPA. And all images were calculated by complex subtraction from the background mask in a work station. In normal volunteers, the quality of images of time-resolved projection MRA was satisfactory. The arteries from internal carotid artery through M 2 segment of middle cerebral artery and all major venous systems were well portrayed. In 4 cases of IC occlusion who were assessed the collateral flow through the anterior communicating artery and posterior communicating artery, there were delayed to demonstrate the ipsilateral MCA. However, in 2 cases of IC occlusion that were assessed the collateral flow through leptomeningeal anastomosis, ipsilateral MCA and collateral circulation were not demonstrated. In all patients of post EC/IC bypass surgery, the patency of EC/IC bypass could be evaluated as properly with time-resolved projection MRA as 3 D-TOF MRA. Although the temporal and spatial resolutions are insufficient, time-resolved projection MRA was powerful non-invasive method to evaluate the cerebral hemodynamics via the basal communicating arteries in IC occlusion and identify the patency of EC/IC bypass.
authors: Department of Neurological Surgery, Washokai Sadamoto Hospital, 1-6-1, Takewara-cho, Matsuyama, Ehime 790-0052, Japan.
authors: Y
authors: Y
authors: Oka
authors: K
authors: K
authors: Kusunoki
authors: I
authors: I
authors: Nochide
authors: K
authors: K
authors: Igase
authors: H
authors: H
authors: Harada
authors: K
authors: K
authors: Sadamoto
authors: K
authors: K
authors: Nagasawa
mesh_terms: D000328:Adult; D000368:Aged; D002548:Cerebral Revascularization; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000503:physiopathology; D003097:Collateral Circulation; D005260:Female; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis / Q000503:physiopathology; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D013997:Time Factors