title: Association between urinary tract infection, renal damage and birth size.
abstract: The aim of this study was to investigate whether birth size is associated with permanent renal damage in children with urinary tract infection (UTI). A cohort of 1221 children under 16 y of age was diagnosed with their first symptomatic UTI between 1970 and 1979. Of these, 74 had urographic renal scarring in childhood and 57 were re-examined as adults. The birth files of 48 of these patients (35F, 13M) were available, and birthweight and birthlength in relation to gestational age were analysed and compared with a Swedish reference population. Children who had renal damage without vesicoureteric reflux were significantly smaller at birth (median weight, -0.76 SDS) compared with both children who had renal damage and reflux (median weight, -0.01 SDS) and the reference population.
  
  
  CONCLUSIONS
  The demonstration of low birthweight among children with UTI and renal damage but no reflux suggests that low birthweight may be a risk factor for the development of renal damage.
authors: Department of Radiology, Sahlgrenska University Hospital, Göteborg, Sweden. mikael.hellstrom@xray.gu.se
authors: M
authors: M
authors: Hellström
authors: H
authors: H
authors: Hessel
authors: B
authors: B
authors: Jacobsson
authors: U
authors: U
authors: Jodal
authors: A
authors: A
authors: Niklasson
authors: M
authors: M
authors: Wennerström
authors: A
authors: A
authors: Hellström
mesh_terms: D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D001827:Body Height; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000473:pathology*; D008297:Male; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000209:etiology*