title: Bone reaction induced by femoral stem of titanium alloy endoprosthesis for malignant bone tumors at the distal femur.
abstract: We demonstrated radiological evaluations after limb salvage surgery with an uncemented titanium endoprosthesis possessing a rotating hinge-type knee joint for 7 patients with malignant bone tumors at the distal femur. Although radiographically, cortical hypertrophy and new bone formation at the junction between implant and cortex appeared in all cases, there was a small quantity of subsidence of the implant in all cases. Loosening of the stem was found in 2 patients at 4 and 9 years after surgery. However, after revision surgery, the function restored as before. The latest average functional score according to the system of the International Society of Limb Salvage was good, being 73%.
authors: Department of Orthopaedic Surgery, Ayabe Municipal Hospital, 20-1 Otsuka, Aono-cho, Ayabe city, Kyoto 623-0011, Japan. naka_s@f5.dion.ne.jp
authors: S
authors: S
authors: Nakamura
authors: K
authors: K
authors: Kusuzaki
authors: H
authors: H
authors: Murata
authors: H
authors: H
authors: Takeshita
authors: M
authors: M
authors: Hirata
authors: S
authors: S
authors: Hashigushi
authors: Y
authors: Y
authors: Hirasawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000497:Alloys; D001846:Bone Development; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005500:Follow-Up Studies; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D007720:Knee Prosthesis / Q000009:adverse effects*; D008297:Male; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation; D014025:Titanium / Q000009:adverse effects*
chemical_list: D000497:Alloys; C031462:titanium alloy (TiAl6V4); D014025:Titanium