Reversible encapsulation by self-assembling resorcinarene subunits.
Encapsulation complexes are assemblies in which a reversibly formed host more or less completely surrounds guest molecules. Host structures held together by hydrogen bonds have lifetimes in organic solvents of milliseconds to hours, long enough to directly observe the encapsulated guest by NMR spectroscopy. We describe here the action of alkyl ammonium compounds as guests that gather up to six molecules of the host module to form encapsulation complexes. The stoichiometry of the complexes--the largest hydrogen-bonded host capsules to date--is determined by the size and concentration of the guest.
Shivanyuk
A
A
The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, MB-26, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Rebek
J
J
D006859:Hydrogen; D009682:Magnetic Resonance Spectroscopy; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*
D000644:Quaternary Ammonium Compounds; D006859:Hydrogen