Mammalian development: axes in the egg?
An enduring but erroneous belief is that the post-fertilisation period is irrelevant for axis development in mammals. Two recent studies further undermine this belief. Is information for axial developmental encoded in the egg cortex?
Johnson
M H
MH
Department of Anatomy, Downing Street, Cambridge CB3 3DY, UK. mjh@mole.bio.cam.ac.uk
D000818:Animals; D001755:Blastocyst / Q000502:physiology; D019521:Body Patterning; D002455:Cell Division; D005314:Embryonic and Fetal Development; D005306:Fertilization; D006801:Humans; D008322:Mammals; D051379:Mice; D009030:Mosaicism; D010063:Ovum / Q000254:growth & development / Q000502:physiology*; D010944:Plants / Q000196:embryology; D014327:Trophoblasts / Q000502:physiology