Evaluation of the biological activity of crude extracts from plants used in Yucatecan traditional medicine. Part II. DNA-interacting activity.
Extracts from leaves, stems, and roots of twelve plants used commonly in Yucatecan traditional medicine were evaluated in the DNA-methyl green assay. Twenty one extracts showed DNA-interacting activity, and nine of them, belonging to five plant species, presented a displacement activity of 5% or higher. The highest activity (17.6%) was detected in the leaf extract of Heliotropium angiospermum.
Sánchez-Medina
A
A
Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, Mérida, México.
García-Sosa
K
K
May-Pat
F
F
Peña-Rodríguez
L M
LM
D004247:DNA / Q000187:drug effects*; D004353:Drug Evaluation, Preclinical; D004996:Ethidium / Q000494:pharmacology; D008519:Medicine, Traditional; D008739:Methyl Green; D008800:Mexico; D008954:Models, Biological; D010598:Pharmacognosy; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D018514:Plant Structures; D010946:Plants, Medicinal
D010936:Plant Extracts; D008739:Methyl Green; D004247:DNA; D004996:Ethidium