There may never be a final cure for breast cancer.
This paper challenges the perception that the success of the human genome project has brought us to the threshold of a cure for many common cancers. Paradoxically, the message emerging from the genetics of breast cancer may be that the genetic damage associated with malignant transformation, and the mutations predisposing to the disease in our gene pool, may prove impossible to eliminate.
Barr
L
L
Department of Surgery, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.
Evans
D G
DG
D001943:Breast Neoplasms / Q000235:genetics* / Q000517:prevention & control / Q000628:therapy*; D005260:Female; D019398:Genes, BRCA1; D016147:Genes, Tumor Suppressor; D015316:Genetic Therapy; D016045:Human Genome Project; D006801:Humans; D009154:Mutation