title: Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou Village), Anhui Province, China: II. Seroepidemiological studies of the age relationships of serum antibody levels and infection status.
abstract: Anti-hookworm antibody serologic responses were measured in residents of an Anhui provincial Chinese village where Ancylostoma duodenale is the predominant hookworm. Antibody responses were measured against either soluble infective third-stage larval (L3) or adult antigens. Immunoglobulins of the IgG class, especially IgG4 correlated with both the prevalence and intensity of A. duodenale hookworm infections. In contrast, there was an inverse correlation with IgM, but no correlation with IgA or IgE. Circulating IgG4 antibody responses might serve as a surrogate marker for active A. duodenale hookworm infection.
authors: Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine, Shanghai. xuehc@yahoo.com
authors: X
authors: X
authors: Haichou
authors: W
authors: W
authors: Yan
authors: X
authors: X
authors: Shuhua
authors: L
authors: L
authors: Sen
authors: W
authors: W
authors: Yong
authors: S
authors: S
authors: Guangjin
authors: W
authors: W
authors: Weituo
authors: Z
authors: Z
authors: Bin
authors: L
authors: L
authors: Drake
authors: F
authors: F
authors: Zheng
authors: P J
authors: PJ
authors: Hotez
mesh_terms: D000724:Ancylostomiasis / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000473:pathology; D000909:Antibodies, Helminth / Q000097:blood*; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D015995:Prevalence; D012423:Rural Health; D016036:Seroepidemiologic Studies
chemical_list: D000909:Antibodies, Helminth