Aggravation of food-related behavior in an adolescent with Prader-Willi syndrome treated with fluvoxamine and fluoxetine.
Prader-Willi Syndrome is a congenital multisystem disorder, characterized by a typical dysmorphism, mental retardation, hyperphagia due to insatiable appetite, and resultant morbid obesity. Psychiatric symptoms include obsessions and temper tantrums.


METHODS
Pharmacotherapy is experimental with a few reports of successful fluoxetine treatment.


RESULTS
We report an aggravation in the food-related symptoms and a consequent weight gain in an adolescent with Prader-Willi syndrome, who was treated with fluvoxamine and fluoxetine.
Kohn
Y
Y
Department of Psychiatry, Hebrew University-Hadassah School of Medicine, Jerusalem, Israel. kohn@md2.huji.ac.il
Weizman
A
A
Apter
A
A
D000293:Adolescent; D001068:Feeding and Eating Disorders / Q000139:chemically induced*; D005473:Fluoxetine / Q000009:adverse effects* / Q000627:therapeutic use; D016666:Fluvoxamine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011218:Prader-Willi Syndrome / Q000209:etiology*; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use
D005473:Fluoxetine; D016666:Fluvoxamine; D017367:Selective Serotonin Reuptake Inhibitors