title: Hypophosphataemia in the metabolic syndrome. Gender differences in body weight and blood glucose.
abstract: OBJECTIVE
  We examined gender differences in the clustering of risk factors, especially regarding the possible role of serum phosphate (S-P) in obese patients who participated in a 4 week education programme to reduce their excess risk of cardiovascular disease (CVD).
  
  
  RESULTS
  Significantly higher body mass index (BMI) and concentrations of S-P and high density lipids (S-HDL) in serum were found in women (n=1272) than in men (n=993). In women, BMI was inversely correlated with S-P at the time of admission. Also in women (but not in men), changes in BMI and S-P over 1 or 1-1/2 y were inversely correlated. In men (but not in women), S-P level was inversely correlated with age, systolic blood pressure (SBP), diastolic blood pressure (DBP) and blood glucose at the time of admission. In women, S-P increased and DBP decreased, in addition to weight decrease over both 6 months and 1(1/2) y or 1 y. In women (but not in men), significantly higher age, S-P, S-chol, S-TG, S-urate, SBP and DBP values were found with the highest vs the lowest decile of S-Ca.
  
  
  CONCLUSIONS
  We conclude that higher S-P and S-Ca levels may contribute to the difference in metabolic disturbances occurring in obesity, seen in women vs men.
authors: Department of Social Medicine, University Hospital, Umeå, Sweden. lena.haglin.us@vll.se
authors: L
authors: L
authors: Håglin
authors: A
authors: A
authors: Lindblad
authors: L O
authors: LO
authors: Bygren
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D001794:Blood Pressure; D015992:Body Mass Index; D001835:Body Weight / Q000502:physiology*; D002118:Calcium / Q000097:blood*; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology*; D016000:Cluster Analysis; D005260:Female; D006801:Humans; D017674:Hypophosphatemia; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000503:physiopathology; D010101:Oxygen Consumption; D010710:Phosphates / Q000097:blood; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D001786:Blood Glucose; D008055:Lipids; D010710:Phosphates; D002118:Calcium