Synthesis of (+/-)-puraquinonic acid: an inducer of cell differentiation.
Puraquinonic acid (1) was synthesized from 2,5-dimethoxybenzoic acid by way of isochroman 2 and the indanone derivative 3, a Nazarov cyclization being used to construct the five-membered ring.
Clive
D L
DL
Chemistry Department, University of Alberta, Edmonton, Alberta, Canada T6G 2G2. derrick.clive@ualberta.ca
Sannigrahi
M
M
Hisaindee
S
S
D002455:Cell Division / Q000187:drug effects*; D007192:Indenes / Q000138:chemical synthesis*; D013057:Spectrum Analysis
D007192:Indenes; C431681:puraquinonic acid