title: Bisoprolol treatment for cyanotic spells--a 69-year-old female with uncorrected pentalogy of Fallot.
abstract: Pentalogy of Fallot is a rare cyanotic congenital heart disease characterized by biventricular origin of the aorta above a large ventricular septal defect, obstruction of the pulmonary outflow, right ventricular hypertrophy (tetralogy of Fallot), and an atrial septal defect. Mortality due to syncope, arrhythmia or congestive heart failure is about 75% by the age of 10 years and 97% by the age of 40. We report a 69-year old female with uncorrected pentalogy of Fallot who suffered from recurrent syncope during classic cyanotic spells. Treatment with bisoprolol is recommended in symptomatic children and also improved symptoms in our patient. We conclude that single patients with pentalogy of Fallot reach the seventh decade and that cyanotic congenital heart disease is a rare cause of syncope in the elderly.
authors: Medizinische Poliklinik, Universität Munich, Pettenkoferstr. 8a, D-80336 Munich, Germany. hjanders@clinbio.med.uni-muenchen.de
authors: H J
authors: HJ
authors: Anders
authors: S
authors: S
authors: Fuchshuber
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000368:Aged; D017298:Bisoprolol / Q000627:therapeutic use*; D002648:Child; D003490:Cyanosis / Q000188:drug therapy; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D013575:Syncope / Q000188:drug therapy; D013771:Tetralogy of Fallot / Q000150:complications* / Q000188:drug therapy*
chemical_list: D000319:Adrenergic beta-Antagonists; D017298:Bisoprolol