Administration of NF-kappaB decoy inhibits pancreatic activation of NF-kappaB and prevents diabetogenesis by alloxan in mice.
Quan
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N
Department of Oral Biology, The Ohio State University, Columbus, Ohio 43210, USA.
Ho
E
E
La
W
W
Tsai
Y H
YH
Bray
T
T
D000496:Alloxan; D000818:Animals; D017209:Apoptosis; D003921:Diabetes Mellitus, Experimental / Q000517:prevention & control*; D004195:Disease Models, Animal; D006943:Hyperglycemia / Q000139:chemically induced / Q000517:prevention & control; D007328:Insulin / Q000096:biosynthesis; D007515:Islets of Langerhans / Q000378:metabolism; D051379:Mice; D016328:NF-kappa B / Q000008:administration & dosage / Q000627:therapeutic use*; D010179:Pancreas / Q000378:metabolism*
D007328:Insulin; D016328:NF-kappa B; D000496:Alloxan