Photoinduced formation of beta-oxy-alpha,alpha-disubstituted-alpha-amino acid derivatives from ketoximes.
[reaction: see text] The first intermolecular radical addition onto ketoxime ethers is described. beta-Oxygenated quaternary alpha-amino acid derivatives IotaIota were obtained upon irradiation of alpha-alkoxycarbonyl ketoxime ethers Iota in the presence of suitable alpha-alkoxy carbon radical precursors and a sensitizer.
Torrente
S
S
Departamento de Química Orgánica y Unidad Asociada al CSIC Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
Alonso
R
R
D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D004987:Ethers / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*; D010777:Photochemistry
D000596:Amino Acids; D004987:Ethers; D010091:Oximes