Rapid regression of primary pulmonary hypertension.
A 14 month old child presented for investigation of tachypnoea. No parenchymal lung disease was shown on chest x ray. On echocardiography there was normal intracardiac anatomy with significant pulmonary hypertension. At cardiac catheterisation the presence of primary pulmonary hypertension was confirmed, with a partial response to inhaled nitric oxide (80 ppm) and 100% oxygen. The child was referred for assessment for heart-lung transplantation while maintained on oxygen, inhaled nitric oxide, and nifedipine. Repeat cardiac catheterisation two months after presentation showed complete normalisation of the pulmonary artery pressures.
McMahon
C J
CJ
The Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Fannin 6621, Houston, Texas 77030, USA. cmcmahon@bcm.tmc.edu
Kadkin
J
J
Nihill
M R
MR
D002121:Calcium Channel Blockers / Q000627:therapeutic use; D006328:Cardiac Catheterization; D003131:Combined Modality Therapy; D004452:Echocardiography; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D007223:Infant; D009543:Nifedipine / Q000627:therapeutic use; D009569:Nitric Oxide / Q000627:therapeutic use; D010102:Oxygen Inhalation Therapy; D012075:Remission, Spontaneous
D002121:Calcium Channel Blockers; D009569:Nitric Oxide; D009543:Nifedipine