title: Antibiotic activities of peptides, hydrogen peroxide and peroxynitrite in plant defence.
abstract: Genes encoding plant antibiotic peptides show expression patterns that are consistent with a defence role. Transgenic over-expression of defence peptide genes is potentially useful to engineer resistance of plants to relevant pathogens. Pathogen mutants that are sensitive to plant peptides in vitro have been obtained and a decrease of their virulence in planta has been observed, which is consistent with their hypothetical defence role. A similar approach has been followed to elucidate the potential direct anti-microbial role of hydrogen peroxide. Additionally, a scavenger of peroxynitrite has been used to investigate its involvement in plant defence.
authors: Departamento de Biotecnología - UPM, ETS Ingenieros Agrónomos, E-28040, Madrid, Spain. olmedo@bit.etsia.upm.es
authors: F
authors: F
authors: García-Olmedo
authors: P
authors: P
authors: Rodríguez-Palenzuela
authors: A
authors: A
authors: Molina
authors: J M
authors: JM
authors: Alamillo
authors: E
authors: E
authors: López-Solanilla
authors: M
authors: M
authors: Berrocal-Lobo
authors: C
authors: C
authors: Poza-Carrión
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism*; D018407:Bacterial Physiological Phenomena; D023082:Defensins / Q000235:genetics / Q000378:metabolism*; D006861:Hydrogen Peroxide / Q000378:metabolism*; D009566:Nitrates / Q000378:metabolism*; D016877:Oxidants / Q000378:metabolism; D018515:Plant Leaves / Q000378:metabolism; D018521:Plant Physiological Phenomena; D010944:Plants / Q000235:genetics / Q000382:microbiology*; D011549:Pseudomonas / Q000378:metabolism / Q000472:pathogenicity; D014527:Uric Acid / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D023082:Defensins; D009566:Nitrates; D016877:Oxidants; C039642:peroxynitric acid; D014527:Uric Acid; D006861:Hydrogen Peroxide