[Post-prandial plasma glucose test as screening tool for gestational diabetes: A prospective randomized trial].
OBJECTIVE
To compare one hour postprandial glucose measurements with the one hour 50gm plasma glucose test as predictors of gestational diabetes.


METHODS
One hundred women at 24-28 weeks' gestation were prospectively randomized for both screening methods: one hour postprandial and one hour 50gm plasma glucose test with a one-week-interval between tests. A week later a formal 2-hour 75gm glucose tolerance test was done in each case.


RESULTS
Of the 95 patients who completed the study 13 had gestational diabetes (13.6%). For a threshold of 7.1mmol/l the sensitivity of 1-hour postprandial plasma glucose screening test was 84.6% with a specificity of 87.8%. These values were respectively 84.6% and 81.7% for 1-hour 50 gm plasma glucose test screening test. A threshold of 7.7mmol/l yielded a sensitivity of 60.5% with a specificity of 91.4% for the 1-hour postprandial plasma glucose screening test (69.2% and 86.5% for 1-hour 50gm plasma glucose test)


CONCLUSIONS
In our study the 1-hour postprandial plasma glucose screening test was as effective as the 1-hour 50 gm plasma glucose test screening test for gestational diabetes.
Hidar
S
S
CHU F. Hached, 4000, Sousse, Tunisie. hidar.samir@gnet.tn
Chaïeb
A
A
Baccouche
S
S
Laradi
S
S
Fkih
M
M
Milled
A
A
Khaïri
H
H
D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D016640:Diabetes, Gestational / Q000175:diagnosis*; D005260:Female; D005502:Food; D005865:Gestational Age; D005951:Glucose Tolerance Test; D006801:Humans; D011247:Pregnancy; D011446:Prospective Studies; D012372:ROC Curve; D012680:Sensitivity and Specificity
D001786:Blood Glucose