Synthetic derivatives of abietic acid with radical scavenging activity.
In this work, studies on the arylation of anilines derived from dehydroabietic acid, the main component of disproportionated rosin, are presented. The redox properties of the new diarylamines were investigated by cyclic voltammetry, and their free radical scavenging activity was tested by reduction of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Three of the diarylamines with lower oxidation potential proved to be as active as isopropyldiphenylamine (IPPD) and superior to tert-butylhydroxytoluene (BHT), both commercially available synthetic antioxidants.
Esteves
M A
MA
INETI, Departamento de Tecnologia de Indústrias Químicas, Estrada do Paço do Lumiar, 22, 1649-038 Lisboa, Portugal.
Narender
N
N
Marcelo-Curto
M J
MJ
Gigante
B
B
D045784:Abietanes; D001729:Bismuth; D002384:Catalysis; D003300:Copper; D004224:Diterpenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D004563:Electrochemistry; D016166:Free Radical Scavengers / Q000138:chemical synthesis / Q000737:chemistry* / Q000302:isolation & purification; D007202:Indicators and Reagents; D010616:Phenanthrenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
D045784:Abietanes; D004224:Diterpenes; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D010616:Phenanthrenes; D003300:Copper; D001729:Bismuth; C023710:abietic acid