Growth hormone deficiency in autoimmune polyglandular disease type 1.
This is a case report of 2 patients who were diagnosed to have autoimmune polyglandular disease type 1. Both developed mucocutaneous candidiasis, hypoparathyroidism, vitiligo, and adrenocortical insufficiency. Both were noticed to have subnormal linear growth velocity and delayed bone age. Both showed subnormal stimulated serum growth hormone values indicating growth hormone deficiency. The first case showed favorable response to growth hormone therapy.
Al-Herbish
A S
AS
Department of Pediatrics (39), College of Medicine, King Saud University, PO Box 90533, Riyadh 11623. asalherbish@yahoo.com
Bailey
J D
JD
Kooh
S W
SW
D000293:Adolescent; D000309:Adrenal Insufficiency / Q000209:etiology; D002178:Candidiasis, Chronic Mucocutaneous / Q000209:etiology; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013006:Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use; D006801:Humans; D007011:Hypoparathyroidism / Q000209:etiology; D008297:Male; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications* / Q000175:diagnosis; D014820:Vitiligo / Q000209:etiology
D013006:Growth Hormone