[Clinical diagnostic assay of allergic patients with pollen extract from Parthenium hysterophorous L].
OBJECTIVE
There are no antecedents in Cuba of studies developed to prove the efficacy of on allergy test to pollen Parthenium hysterophorus L.


OBJECTIVE
Evaluate the allergenic extract pollen Parthenium hysterophorus L elaborated at the reference hospital William Soler City Havana.


METHODS
We selected 100 patients with a positive clinic history of inhalant allergy and 100 healthy person. All the persons selected were skin prick tested with dillution's of the extract (1:100 and 1:1000 P/V) and positive and negative control. We measured the average diameter of the wheal and the perpendicular diameter, then we calculated the average. We also calculated size of the wheal in the duplicated, which constituted the size of the reaction. We estimated the validity of the test calculating the sensibility and specificity. We used the EPITABLE program to do this.


RESULTS
The skin prick tested positive in 79% of the patients and 9% in the healthy persons, for a sensitivity of 79% the interval of confidence (IC), 69.5, 86.2 and specificity of 91%, IC 83.2, 95.5, the predictive positive value 89.8% IC 81.04, 94.9 and the predictive negative value 81.3%, IC 72.5, 87.8.


CONCLUSIONS
The allergenic extract of Parthenium hysterophorus L in very sharp to test the allergy to his pollen produced by the allergology laboratory of Hospital William Soler, is efficacy by diagnostic of the alterations caused by this pollen.
Rodríguez Santos
O
O
Servicio de alergia, Hospital Wilian Soler, Ciudad Habana, Cuba.
Rodríguez Gavaldá
R
R
Silva Pérez
R
R
D000293:Adolescent; D000328:Adult; D019659:Asteraceae / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003462:Cuba; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011058:Pollen / Q000276:immunology*; D012882:Skin Tests