title: Palladium and Raney nickel catalyzed methanolic cleavage of stable borane-amine complexes.
abstract: [figure: see text] Palladium and Raney nickel were found to catalyze the methanolysis of borane-amine adducts. Hence, strongly complexed amines can now be liberated by simple treatment with Pd/C or Raney Ni in methanol. The method is applicable to primary, secondary, tertiary, and aromatic amines, and the mildness of the reaction conditions allows preservation of otherwise labile functional groups.
authors: Pfizer Global Research and Development, Eastern Point Road, P.O. Box 8013, Groton, Connecticut 06340-8013, USA. michel_a_couturier@groton.pfizer.com
authors: M
authors: M
authors: Couturier
authors: J L
authors: JL
authors: Tucker
authors: B M
authors: BM
authors: Andresen
authors: P
authors: P
authors: Dubé
authors: J T
authors: JT
authors: Negri