title: The benefits of a broader perspective in case-finding for disease management of depression: early lessons from the PROSPECT Study.
abstract: The PROSPECT (Prevention of Suicide in Primary Care Elderly - Collaborative Trial) Study evaluates collaborative care for the treatment of current depressive disorders in older primary care patients. Using screening data, we evaluate implications of expanding the focus to additional patients who report taking psychotropic medication or having a history of depression. Some 13.8% of the patients screened were taking a psychotropic medication and 7.3% were both taking an antidepressant and had a Center for Epidemiologic Studies - Depression Scale (CES-D) score of > 15. Patients who reported current antidepressant use and those with a history of depression also had elevated CES-D scores. Conversely, most patients having an elevated CES-D score also reported taking an antidepressant or having a history of depression. These latter criteria for potential caseness yielded a larger number of patients than those identified by the CES-D alone. More comprehensive approaches to the management of depression should attend to patients already taking psychotropic medication and symptomatic patients with a history of depression, as well as those with current syndromal depression.
authors: Intervention Centers for Late-Life Mood Disorders, Departments of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
authors: J C
authors: JC
authors: Coyne
authors: G
authors: G
authors: Brown
authors: C
authors: C
authors: Datto
authors: M L
authors: ML
authors: Bruce
authors: H C
authors: HC
authors: Schulberg
authors: I
authors: I
authors: Katz
mesh_terms: D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use; D003866:Depressive Disorder / Q000175:diagnosis* / Q000517:prevention & control / Q000628:therapy; D019468:Disease Management; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011320:Primary Health Care; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D011619:Psychotropic Drugs / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D000928:Antidepressive Agents; D011619:Psychotropic Drugs