[Outbreak of Dengue-2 virus in Salta, Argentina, 1988].
Dengue (DEN) reemergence was first detected in Salta, Argentina, in 1997. It was confirmed by serology and PCR that DEN-2 virus was responsible for sporadic cases and indigenous transmission. A laboratory-based surveillance system allowed the detection of an outbreak in Salta several months later. In total, 378 DEN cases were laboratory diagnosed out of 646 (58%) studied. The cases were distributed in 10 localities of the province between January 3rd and May 31st, 1998. One DEN-2 viral isolation and 4 PCR products were obtained from patients coming from Orán and Embarcación localities. Male and female cases occurred at a similar rate (1:1), with adult cases (82.5%) nearly five times greater than for children under 15 years-old (17.5%). Clinically, all cases corresponded to classic DEN. This is the first time that a DEN outbreak has been laboratory-diagnosed in Argentina and also the first time that DEN virus has been isolated in this country.
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Instituto Nacional de Enfermedades Virales Humanas (INEVH) Dr. Julio I. Maiztegui, ANLIS, Monteagudo 2510, 2700 Pergamino, Argentina.
Rangeon
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Baroni
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Paz
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Monteros
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Sartini
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Enria
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D000293:Adolescent; D000328:Adult; D000368:Aged; D001118:Argentina / Q000453:epidemiology; D002648:Child; D003715:Dengue / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D003716:Dengue Virus / Q000145:classification / Q000302:isolation & purification*; D004196:Disease Outbreaks; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011159:Population Surveillance; D016036:Seroepidemiologic Studies