title: Sequence and organization of the mitochondrial genome of the Chagas disease vector, Triatoma dimidiata.
abstract: The 17 019 bp mitochondrial genome of Triatoma dimidiata is composed of thirteen protein coding sequences, twenty-two tRNAs, small and large ribosomal units, and a control region. The gene order and orientation are identical to that of Drosophila yakuba. The nucleotide composition is biased toward adenine and thymine (69.5% A + T). The 2.1 kb putative control region, known as the A + T rich region in most insects, has an A + T bias of 66%, but contains a 400 bp sequence that is 77.5% A + T and two other distinct regions: (1) one with a lower A + T bias (60.1%) and (2) a region of eight tandem repeat units. The identified 1.4 kb nuclear copy of mitochondrial sequences encompasses the string of Gs and the beginning of the cytochrome c oxidase 1 gene but lacks the 1.8 kb region spanning the eight tandem repeats and the 5' end of the NADH dehydrogenase subunit II gene.
authors: Centers for Disease Control and Prevention, National Center for Infectious Diseases, Division of Parasitic Diseases, Entomology Branch, Mailstop F-22, Atlanta, Georgia 30341, USA. ebd6@cdc.gov
authors: E M
authors: EM
authors: Dotson
authors: C B
authors: CB
authors: Beard
mesh_terms: D000818:Animals; D001483:Base Sequence; D002467:Cell Nucleus; D014355:Chagas Disease; D018076:DNA, Complementary; D004272:DNA, Mitochondrial; D017344:Genes, Insect; D008928:Mitochondria; D008969:Molecular Sequence Data; D014224:Triatoma / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; D004272:DNA, Mitochondrial