Effects of various modes of sonication with low frequency ultrasound on in vitro survival of human tumor cells.
The effect of low frequency ultrasound in the cavitation (5-15 sec exposure) and subcavitation (5-210 sec exposure) modes on in vitro survival of cultured human tumor cells was studied. Analysis of the dose-effect curves and mathematical estimation of the effects low-frequency ultrasonication in the subcavitation mode on cell membranes helped to choose time intervals of tumor cell sonication ensuring potentiation of the cytostatic effects.
Sergeeva
N S
NS
P. A. Gertsen Moscow Oncological Institute.
Sviridova
I K
IK
Nikolaev
A L
AL
Ambrozevich
E G
EG
Kabisov
R K
RK
Sarantseva
O S
OS
Kurilyak
O A
OA
Al'kov
S V
SV
Sokolov
V V
VV
D002470:Cell Survival; D006801:Humans; D066298:In Vitro Techniques; D014407:Tumor Cells, Cultured; D014465:Ultrasonics