title: [Masquerade of sebaceous gland carcinoma as a rapidly recurring "chalazion", a case report].
abstract: OBJECTIVE
  Demonstration of the importance of surgical excision and histological examination in presence of an apparently harmless tumoral alteration of the eyelids.
  
  
  METHODS
  We report the case of a 65 year old patient suffering from systemic lupus erythematosus who noted a tumoral lesion on his left lower eyelid. Suspecting a chalazion, his dermatologist simply performed a cauterization. Six weeks later, a recurrence of the tumor appeared at the same location, and again, cauterization was done. A few weeks later, the patient consulted our clinic with a polycyclic tumor of 5 mm in diameter, involving the lid margin of the temporal part of the lower left eyelid. The patient had only moderate signs of blepharitis. There were no palpable preauricular and cervical lymph nodes. Suspecting a malignant tumor, the entire tumoral lesion was removed surgically.
  
  
  RESULTS
  The histopathologic examination showed a highly differentiated sebaceous gland carcinoma, most probably originating from a meibomian gland. The margins of the excision were found to be tumor-free.
  
  
  CONCLUSIONS
  Sebaceous cell carcinoma is a rare entity. Depending on its histological differentiation it can be highly malignant. Infiltrative, and can metastasize. The mortality may reach 30% if low differentiation is present. As illustrated in the present case, the lesion may masquerade a chalazion. Therefore, in case of atypical lesion of the eyelid region complete surgical removal followed by a histopathological examination should be performed.
authors: Oculoplastic Surgery Unit, University Eye Clinic, Mittlere Strasse 91, PO Box, CH-4012 Basel, Switzerland.
authors: D M
authors: DM
authors: Gerber
authors: P
authors: P
authors: Meyer
authors: J O
authors: JO
authors: Messerli
authors: J M
authors: JM
authors: Piffaretti
authors: I O
authors: IO
authors: Haefliger
mesh_terms: D018266:Adenocarcinoma, Sebaceous / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000368:Aged; D017043:Chalazion / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005143:Eyelids / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008537:Meibomian Glands / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery