The cell division genes (ftsE and X) of Aeromonas hydrophila and their relationship with opsonophagocytosis.
A transposon mutant from Aeromonas hydrophila AH-3 was obtained which was highly resistant to opsonophagocytosis. The mutation was identified in the ftsE gene and we characterised the operon ftsY, E and X from this bacterium. These genes, as in enteric bacteria, are neighbours to rpoH. The A. hydrophilia ftsE and X genes were fully able to complement Escherichia coli ftsE mutants, and also complement the opsonophagocytosis-resistant phenotype of the A. hydrophila mutant strain. This phenotype seems to be related to the filamentous phenotype at 37 degrees C exhibited by the A. hydrophila ftsE mutant.
Merino
S
S
Departamento Microbiología, Facultad Biología, Universidad de Barcelona, Spain.
Altarriba
M
M
Gavín
R
R
Izquierdo
L
L
Tomás
J M
JM
D018528:ATP-Binding Cassette Transporters; D016980:Aeromonas hydrophila / Q000166:cytology / Q000235:genetics* / Q000254:growth & development; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D001483:Base Sequence; D018797:Cell Cycle Proteins / Q000235:genetics* / Q000378:metabolism; D002455:Cell Division / Q000235:genetics*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics* / Q000378:metabolism; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics / Q000254:growth & development; D029968:Escherichia coli Proteins; D005816:Genetic Complementation Test; D006801:Humans; D066298:In Vitro Techniques; D008969:Molecular Sequence Data; D009504:Neutrophils / Q000382:microbiology / Q000502:physiology*; D009876:Operon; D009895:Opsonin Proteins / Q000097:blood; D010587:Phagocytosis / Q000502:physiology*; D017422:Sequence Analysis, DNA
D018528:ATP-Binding Cassette Transporters; D001426:Bacterial Proteins; C505032:CFTR protein, human; D018797:Cell Cycle Proteins; D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; C491157:FtsX protein, E coli; C102286:FtsX protein, bacteria; D009895:Opsonin Proteins; C075980:FtsE protein, E coli; D019005:Cystic Fibrosis Transmembrane Conductance Regulator