title: Granulomatous slack skin: a distinct disorder or a variant of mycosis fungoides?
abstract: About 75% of cutaneous lymphomas belong to the group of T-cell lymphomas. Mycosis fungoides is the most common entity in this group. Granulomatous slack skin is a rare form of cutaneous T-cell lymphoma closely related to mycosis fungoides. We present here a patient with areas of lax skin for several years who developed a generalized erythroderma with associated immunoactivation and a deterioration in his general condition. This report discusses clinically and histologically the differential diagnoses, namely granulomatous slack skin and granulomatous mycosis fungoides, and suggests that these 2 disorders are only variants in the broad spectrum of a single disease.
authors: Departments of Dermatology, University of Innsbruck, Austria. Gerda.Topar@uibk.ac.at
authors: G
authors: G
authors: Topar
authors: B
authors: B
authors: Zelger
authors: M
authors: M
authors: Schmuth
authors: N
authors: N
authors: Romani
authors: J
authors: J
authors: Thaler
authors: N
authors: N
authors: Sepp
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D002699:Chlorambucil / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D009182:Mycosis Fungoides / Q000175:diagnosis / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D002699:Chlorambucil; D008775:Methylprednisolone