title: Prognostic value of electrocochleography in patients with unilateral Menière's disease undergoing saccus surgery.
abstract: Although a controversial operation, saccus surgery has continued to be used in patients with severe Menière's disease in whom hearing preservation is the objective. The aim of this study was to determine if electrocochleography (ECoG) could predict the patients who would be free of vertigo, 2 and 5 years after surgery. Seventy patients with severe Menière's syndrome underwent ECoG prior to endolymphatic sac surgery. Eighty-four per cent of the patients had an abnormal electrocochleogram. The patients were interviewed 2 and 5 years after surgery. At 2 years, 4/10 (40%) patients with normal ECoG were relieved of dizziness compared to 38/51 (75%) with abnormal ECoG (P < 0.05). At 5 years, 5/8 (63%) patients with normal ECoG were relieved of dizziness compared to 30/30 (100%) with abnormal ECoG (P < 0.001). The patients with a normal ECoG do have less severe measurable hearing impairment (P < 0.05) although they are more likely (P < 0.05) to complain of constant tinnitus. Their history of dizziness is longer and their dizziness more disabling before surgery. In conclusion, patients with a normal ECoG will be less likely to benefit from saccus surgery in the first 5 years. These patients may represent a different nosological entity.
authors: Department of Otolaryngology, Manchester Royal Infirmary, Manchester, UK.
authors: A E
authors: AE
authors: Camilleri
authors: K L
authors: KL
authors: Howarth
mesh_terms: D000328:Adult; D001300:Audiometry, Evoked Response; D004244:Dizziness / Q000175:diagnosis; D018159:Endolymphatic Hydrops / Q000601:surgery; D004712:Endolymphatic Sac / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis / Q000601:surgery*; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies