title: [Regional diastolic function is more preserved in viable than non-viable myocardium. Demonstration by pulsed-wave Doppler tissue imaging in basal conditions].
abstract: OBJECTIVE
  The aim of this study was to analyze the differences in regional diastolic function between viable and non-viable myocardium when assessed by pulsed-wave Doppler tissue imaging performed in basal conditions.
  
  
  METHODS
  The study population included 21 patients with three-vessel disease and regional systolic dysfunction. These patients underwent transthoracic echocardiographic study and pulsed-wave Doppler tissue imaging in basal conditions and, in addition, stress echocardiography with dobutamine performed by a different investigator.
  
  
  RESULTS
  Three-hundred and twenty-two segments were studied, 140 of which (43%) had systolic dysfunction. Of the 140 segments with systolic dysfunction, 52 (37%) were considered hypokinetic by transthoracic echocardiography, 80 (57%) akinetic and 8 (6%) dyskinetic. As assessed by dobutamine echocardiography, 67 segments (48%) were considered viable and 73 (52%) non-viable. Viable segments had a higher peak velocity of the early diastolic wave e (5.5 +/- 1.9 vs. 4.7 +/- 2.0 cm/s; p = 0.03). An e/a ratio < 1 was more frequent in non-viable versus non-viable segments (52 vs. 70%; p < 0.05). There were no differences in relation to regional isovolumetric relaxation time and peak velocity of a wave. Although peak velocity of s wave was lower in non-viable segments, differences were not statistically significant.
  
  
  CONCLUSIONS
  Compared with non-viable segments, viable myocardial segments have less impaired regional diastolic function as assessed by pulsed-wave Doppler tissue imaging.
authors: Hospital Clínico San Carlos. Madrid.
authors: R
authors: R
authors: Moreno
authors: M
authors: M
authors: Angel García-Fernández
authors: J
authors: J
authors: Luis Zamorano
authors: M
authors: M
authors: Moreno
authors: L
authors: L
authors: Pérez De Isla
authors: A
authors: A
authors: Ortega
authors: P
authors: P
authors: Puerta
authors: J
authors: J
authors: Bermejo
authors: C
authors: C
authors: Allúe
authors: J
authors: J
authors: López-Sendón
mesh_terms: D018619:Echocardiography, Doppler, Pulsed; D006321:Heart / Q000502:physiology*; D009206:Myocardium / Q000473:pathology*