title: Displacement of breast tissue and needle deviations during stereotactic procedures.
abstract: OBJECTIVE
  The aim of this study was to quantify the displacement of breast tissue and the inaccuracy of needle positioning for biopsy (14-gauge) and localization (19.5-gauge) needles.
  
  
  METHODS
  For displacement of breast tissue, differences between the coordinates of identifiable microcalcifications in the images before (baseline) and after needle positioning were analyzed (n = 52). For accuracy of needle positioning, differences between the coordinates of the needle tip and the target were analyzed in breast tissue (n = 97) and in air (n = 246).
  
  
  RESULTS
  Average target displacement was 2.1 mm for biopsy needles (95% prediction interval [PI] 0.6-7.8) and 1.0 mm (95% PI 0.3-3.9) for localization needles. Mean inaccuracy of needle positioning in breast tissue was 1.1 mm (95% PI 0.4-3.0) and 1.8 mm (95% PI 0.7-4.6) for biopsy and localization needles, respectively.
  
  
  CONCLUSIONS
  Tissue and needle displacements cause a total positioning error of 2.4 mm in stereotactic core biopsy, which will limit the attainable diagnostic accuracy.
authors: Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. deur@nki.nl
authors: E E
authors: EE
authors: Deurloo
authors: K G
authors: KG
authors: Gilhuijs
authors: L J
authors: LJ
authors: Schultze Kool
authors: S H
authors: SH
authors: Muller
mesh_terms: D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008327:Mammography; D009068:Movement; D013238:Stereotaxic Techniques