title: A novel and selective approach to enantiomerically pure bicyclic-trans-lactams via a titanium enolate of a thiopyridyl ester.
authors: Glaxo Wellcome Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K. jwbc16317@glaxowellcome.co.uk
authors: J W
authors: JW
authors: Cooke
authors: M B
authors: MB
authors: Berry
authors: D M
authors: DM
authors: Caine
authors: K S
authors: KS
authors: Cardwell
authors: J S
authors: JS
authors: Cook
authors: A
authors: A
authors: Hodgson
mesh_terms: D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D019272:Leukocyte Elastase / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D010880:Piperidines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D004791:Enzyme Inhibitors; C119405:GW 311616; D010880:Piperidines; D019272:Leukocyte Elastase