title: [Local necrosis of finger following stab with needle used to pump terbutaline sulfate (Bricalin)].
abstract: Terbutaline sulfate (Bricalin) is a widely used medication for asthma. It works mostly, but not only, on beta-adrenergic receptors. In this case study we describe a 50-year-old nurse referred to the emergency department after she was stabbed by needle that was used to draw bricalin for inhalation. She arrived at the emergency room with an inflamed necrotic area at the point of the stab. Later, she developed acute infection that was treated with antibiotics. Following the acute phase there was still a necrotic area, that required surgical debridement. It seems that this is the result of the vasoconstrictive influence of terbutaline sulfate via alpha adrenergic receptors. In the medical literature there is scarce data regarding this side effect.
authors: Departments of Orthopedics and Surgery A, Rabin Medical Center (Hasharon Hospital), Petach-Tikva, Israel.
authors: M
authors: M
authors: Yasin
authors: T H
authors: TH
authors: Vishne
authors: D
authors: D
authors: Hendel
mesh_terms: D000318:Adrenergic beta-Agonists / Q000633:toxicity*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement; D004636:Emergency Service, Hospital; D005260:Female; D005383:Finger Injuries / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007249:Inflammation; D008875:Middle Aged; D009336:Necrosis; D016602:Needlestick Injuries / Q000473:pathology*; D009726:Nurses; D009784:Occupational Diseases / Q000473:pathology*; D013726:Terbutaline / Q000633:toxicity*; D014662:Vasoconstrictor Agents / Q000633:toxicity
chemical_list: D000318:Adrenergic beta-Agonists; D000900:Anti-Bacterial Agents; D014662:Vasoconstrictor Agents; D013726:Terbutaline