title: Reactivation of chronic Chagas' disease following allogeneic bone marrow transplantation and successful pre-emptive therapy with benznidazole.
abstract: This report shows the early detection of reactivation of chronic Chagas' disease (CCd) in a 27-year-old man with chronic myelogenous leukemia undergoing allogeneic bone marrow transplantation (ABMT). Pre-emptive therapy with benznidazole during a period of 7 weeks led to a rapid recovery of the patient, who remains free of parasitemia 2 years after the bone marrow transplantation.
authors: Instituto de Criopreservación y Trasplante de médula ósea, IMA, Buenos Aires, Argentina. jaltclas@intramed.net.ar
authors: J
authors: J
authors: Altclas
authors: A
authors: A
authors: Sinagra
authors: G
authors: G
authors: Jaimovich
authors: C
authors: C
authors: Salgueira
authors: C
authors: C
authors: Luna
authors: A
authors: A
authors: Requejo
authors: V
authors: V
authors: Milovic
authors: A
authors: A
authors: De Rissio
authors: L
authors: L
authors: Feldman
authors: A
authors: A
authors: Riarte
mesh_terms: D000328:Adult; D000818:Animals; D016026:Bone Marrow Transplantation; D014355:Chagas Disease / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy; D008297:Male; D009593:Nitroimidazoles / Q000627:therapeutic use*; D011183:Postoperative Complications; D012008:Recurrence; D014184:Transplantation, Homologous; D014344:Trypanocidal Agents / Q000627:therapeutic use*; D014349:Trypanosoma cruzi / Q000302:isolation & purification
chemical_list: D009593:Nitroimidazoles; D014344:Trypanocidal Agents; C009999:benzonidazole