The changes of cardiac ejection fraction up to 72 h after transfusion in patients with chronic anaemia.
The objective was to assess the serial change of the cardiac function after blood transfusion in patients with chronic anaemia. According to a previous study, transfusion would adjust the ejection fraction to the advantage of cardiac function in chronic anaemia patients, and thus the serial change of the cardiac function in a certain period should be evaluated after transfusion in patients with chronic anaemia. In a prospective study, ejection fraction (EF) was determined before and < or = 6 h, 24 h and 72 h after transfusion in 32 patients with chronic anaemia, and the results were compared and analysed. In the left ventricle (LV), the four EFs noted before and < or = 6 h, 24 h and 72 h after transfusion did not significantly differ between one another. In the right ventricle (RV), the EF 72 h after transfusion significantly increased in comparison with the pretransfusion value (P = 0.043). Transfusion of small amounts of RBC did not significantly change the LVEF up to 72 h in patients with transfusion-dependent chronic anaemia; whether it might change the RVEF 72 h after transfusion deserves further investigation.
Ho
C H
CH
Division of Hematology, Veterans General Hospital, Taipei, Taiwan, ROC. chho@vgtpe.gov.tw
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000503:physiopathology* / Q000628:therapy*; D004906:Erythrocyte Count; D017707:Erythrocyte Transfusion; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006334:Heart Function Tests; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right
D006454:Hemoglobins