Synthesis and absolute configuration of Stellettadine A: a marine alkaloid that induces larval metamorphosis in ascidians.
Stellettadine A, a bisguanidinium alkaloid isolated from a marine sponge Stelletta sp. as an inducer of larval metamorphosis in ascidians, and its unnatural enantiomer were synthesized from the enantiomers of citronellal. The absolute configuration of stellettadine A was established as R.
Nozawa
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Department of Chemistry, Faculty of Science, Science University of Tokyo, Kagurazaka 1-3, Shinjuku-ku, Tokyo 162-8601, Japan.
Takikawa
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Mori
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D000080462:Acyclic Monoterpenes; D000447:Aldehydes / Q000378:metabolism; D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D000818:Animals; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry; D007814:Larva / Q000254:growth & development / Q000502:physiology; D008675:Metamorphosis, Biological / Q000187:drug effects; D039821:Monoterpenes; D011161:Porifera / Q000737:chemistry; D018894:Reverse Transcriptase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism; D014561:Urochordata / Q000196:embryology
D000080462:Acyclic Monoterpenes; D000447:Aldehydes; D000470:Alkaloids; D000935:Antifungal Agents; D039821:Monoterpenes; D018894:Reverse Transcriptase Inhibitors; C107775:stellettadine A; C108217:citronellal