Oxidative stress and mitochondrial damage in coronary artery bypass graft surgery: effects of antioxidant treatments.
We examined antioxidant actions in 73 patients undergoing coronary artery surgery by assessing mitochondrial damage and oxidative stress in ventricular biopsies obtained at preischemia and postreperfusion. Those patients who received antioxidant therapy benefited by less oxidative stress and mitochondrial damage.
Milei
J
J
Facultad de Medicina de la Universidad del Salvador Laboratorio de Radicales Libres en Biología y Medicina Universidad de Buenos Aires, Buenos Aires, Argentina.
Ferreira
R
R
Grana
D R
DR
Boveris
A
A
D000975:Antioxidants / Q000627:therapeutic use*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D008928:Mitochondria / Q000473:pathology*; D018384:Oxidative Stress; D011183:Postoperative Complications / Q000473:pathology / Q000517:prevention & control*
D000975:Antioxidants