[New advances and future perspectives in mammal cloning].
To the great extent, the study and application of transgenic animal are restricted by the inherent limitation of pronuclear microinjection. Recently, the rapid progresses in gene targeting and cloning of somatic cells have shown that the combination of these two technologies will become a virtual way to producing large transgenic animals.
Tan
X H
XH
Institute of Biotechnology, Beijing 100071, China.
Yang
X
X
Huang
P T
PT
D000818:Animals; D030801:Animals, Genetically Modified; D019976:Cloning, Organism; D018390:Gene Targeting; D053652:Nuclear Transfer Techniques