title: Double valve endocarditis.
abstract: BACKGROUND
  There are little data concerning surgical outcomes in patients with native valve endocarditis affecting both the aortic and mitral valves.
  
  
  METHODS
  From 1977 to 1998, 54 patients had simultaneous aortic and mitral valve grafting for native valve endocarditis. In 78%, mitral valve involvement was limited to the anterior leaflet, suggesting a jet lesion from the aortic valve. Surgical strategies included 31 valve repairs and valve replacement with mechanical (34), bioprosthetic (34), or allograft (9) prostheses. Three hundred twenty-five patient-years of follow-up were available for analysis (mean 6.0 +/- 4.8 years).
  
  
  RESULTS
  There were no hospital deaths. Ten-year survival was 73%. Ten-year freedom from recurrent endocarditis was 84%, with risk peaking at 3 months, followed by a constant risk of 1.3%/yr. Choice of valvar procedure did not influence mortality or reinfection risk.
  
  
  CONCLUSIONS
  The most common pattern of double valve infection was a jet lesion on the anterior mitral leaflet. Surgical treatment has late survival and freedom from reinfection similar to those of patients with single heart valve infection.
authors: Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA. gillinom@ccf.org
authors: A M
authors: AM
authors: Gillinov
authors: R
authors: R
authors: Diaz
authors: E H
authors: EH
authors: Blackstone
authors: G B
authors: GB
authors: Pettersson
authors: J F
authors: JF
authors: Sabik
authors: B W
authors: BW
authors: Lytle
authors: D M
authors: DM
authors: Cosgrove
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D001705:Bioprosthesis; D019917:Blood Vessel Prosthesis Implantation; D004697:Endocarditis, Bacterial / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D014184:Transplantation, Homologous; D016896:Treatment Outcome