Hydra constitutively expresses transcripts involved in vertebrate neural differentiation.
The diploblastic Hydra is among the most primitive multicellular organisms. Using cross-hybridization with Xenopus probes, noggin-like transcripts were detected in the hypostome and basal disc of adult Hydra (Pelmatohydra oligactis), regions with properties similar to that of the amphibian organizer. This points to the possibility of a close molecular similarity between the Xenopus and Hydra organizers. The constitutive expression of a noggin-like gene in Hydra may be responsible for its regenerative capacity.
Chatterjee
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Division of Animal Sciences, Agharkar Research Institute, G G Agharkar Road, Pune 411 004, India.
Lahudkar
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S
Godbole
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NN
Ghaskadbi
S
S
D000818:Animals; D002352:Carrier Proteins; D003001:Cloning, Molecular; D051956:Goosecoid Protein; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism*; D006829:Hydra / Q000033:anatomy & histology / Q000235:genetics* / Q000502:physiology; D017403:In Situ Hybridization; D020897:Organizers, Embryonic; D011506:Proteins / Q000235:genetics / Q000378:metabolism*; D012097:Repressor Proteins; D014157:Transcription Factors; D014982:Xenopus laevis / Q000235:genetics; D000099176:Noggin Protein
D002352:Carrier Proteins; D051956:Goosecoid Protein; D018398:Homeodomain Proteins; D011506:Proteins; D012097:Repressor Proteins; D014157:Transcription Factors; D000099176:Noggin Protein