[Antibodies to beta2-glycoprotein-1 in patients with systemic lupus erythematosus].
Antibodies to beta 2-glycoprotein I (beta 2-GPI) and antibodies to cardiolipin (aCL) were determined by enzyme immunoassay in 58 patients with verified SLE. Elevated level of antibodies to beta 2-GPI was associated with development of antiphospholipid syndrome (APS) and aCL hyperproduction. It is evident that synthesis of antibodies to beta 2-GPI is an additional marker of APS in SLE.
Borodin
A G
AG
Baranov
N G
NG
Nasonov
E L
EL
D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000276:immunology*; D016736:Antiphospholipid Syndrome / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008297:Male; D008562:Membrane Glycoproteins / Q000276:immunology; D008875:Middle Aged; D053482:beta 2-Glycoprotein I
D017153:Antibodies, Anticardiolipin; D001323:Autoantibodies; D006023:Glycoproteins; D008562:Membrane Glycoproteins; D053482:beta 2-Glycoprotein I