title: Rectal metastases from lobular carcinoma of the breast: report of a case and literature review.
abstract: Metastatic involvement of the gastrointestinal (GI) tract secondary to breast cancer is rare. Reported herein is the case of a 74-year-old woman with metastatic lobular breast carcinoma to the rectum presenting with obstruction. The breast tumour was diagnosed nine years prior to the presentation of rectal metastases. Endoscopy was repeated twice until a diagnosis was established. Examination of endoscopy material revealed infiltration of the rectum by malignant signet ring cells identical to those of the primary breast tumour. The patient did not respond to chemotherapy and underwent laparotomy with a defunctioning colostomy. Literature review revealed only a few more cases of metastatic breast carcinoma to the rectum. Awareness of this condition may lead to accurate diagnosis and early initiation of systemic treatment, thus avoiding surgical intervention.
authors: Department of Medical Oncology, Ioannina University Hospital, Greece. ariula93@otenet.gr
authors: A
authors: A
authors: Bamias
authors: G
authors: G
authors: Baltayiannis
authors: S
authors: S
authors: Kamina
authors: M
authors: M
authors: Fatouros
authors: E
authors: E
authors: Lymperopoulos
authors: N
authors: N
authors: Agnanti
authors: E
authors: E
authors: Tsianos
authors: N
authors: N
authors: Pavlidis
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018275:Carcinoma, Lobular / Q000556:secondary* / Q000601:surgery; D003125:Colostomy; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology; D015411:Mastectomy, Modified Radical; D012004:Rectal Neoplasms / Q000556:secondary*