Multilevel regulation of the circadian clock.
Living organisms adapt to light-dark rhythmicity using a complex programme based on internal clocks. These circadian clocks, which are regulated by the environment, direct various physiological functions. As the molecular mechanisms that govern clock function are unravelled, we are starting to appreciate simple patterns as well as exquisite layers of regulation.
Cermakian
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Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS-INSERM-Université Louis Pasteur, 1, Rue Laurent Fries, 67404 Illkirch-Strasbourg, France.
Sassone-Corsi
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P
D000818:Animals; D001683:Biological Clocks / Q000235:genetics / Q000502:physiology*; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology*; D008027:Light; D008954:Models, Biological; D009474:Neurons / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D013493:Suprachiasmatic Nucleus / Q000166:cytology / Q000378:metabolism*