Vitamin D deficiency in Iranian mothers and their neonates: a pilot study.
We conducted a pilot study to assess the prevalence of hypovitaminosis D among Iranian women and their newborns. Blood samples were taken from 50 mothers (age 16-40 yr) and their neonates at term delivery in the largest Tehran hospital. The results showed that 80% of the women had 25-hydroxyvitamin D (25-OHD) concentrations of less than 25 nmol/l. Mean maternal plasma calcium and phosphatase alkaline concentrations were in the normal range. The mean maternal serum immunoreactive parathyroid hormone concentration of women with hypovitaminosis D (i.e., 25-OHD levels <25 nmol/l) was above normal range and significantly different from that of women without hypovitaminosis D.


CONCLUSIONS
The mean cord serum 25-OHD concentration was very low (4.94+/-9.4 nmol/l) and that of infants of mother with hypovitaminosis D were almost undetectable (1.2+/-1.2 nmol/l).
Bassir
M
M
Department of Pediatrics, Shohada Hospital, Tehran, Iran.
Laborie
S
S
Lapillonne
A
A
Claris
O
O
Chappuis
M C
MC
Salle
B L
BL
D000293:Adolescent; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood; D007231:Infant, Newborn; D007492:Iran / Q000453:epidemiology; D016014:Linear Models; D009035:Mothers; D010281:Parathyroid Hormone / Q000097:blood; D010865:Pilot Projects; D015995:Prevalence; D011446:Prospective Studies; D014808:Vitamin D Deficiency / Q000097:blood / Q000453:epidemiology*
D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D000469:Alkaline Phosphatase; D002118:Calcium