title: The epidemiology of Plasmodium falciparum malaria in two Cameroonian villages: Simbok and Etoa.
abstract: In support of ongoing immunologic studies on immunity to Plasmodium falciparum, demographic, entomologic, parasitologic, and clinical studies were conducted in two Cameroonian villages located 3 km apart. Simbok (population = 907) has pools of water present year round that provide breeding sites for Anopheles gambiae, whereas Etoa (population = 485) has swampy areas that dry up annually in which A. funestus breed. Results showed that individuals in Simbok receive an estimated 1.9 and 1.2 infectious bites per night in the wet and dry season, respectively, whereas individuals in Etoa receive 2.4 and 0.4 infectious bites per night, respectively. Although transmission patterns differ, the rate of acquisition of immunity to malaria appears to be similar in both villages. A prevalence of 50-75% was found in children < 10 years old, variable levels in children 11-15 years old, and 31% in adults. Thus, as reported in other parts of Africa, individuals exposed to continuous transmission of P. falciparum slowly acquired significant, but not complete, immunity.
authors: Department of Biology, Reiss Science Center, Georgetown University, Washington, District of Columbia 20057, USA.
authors: I A
authors: IA
authors: Quakyi
authors: R G
authors: RG
authors: Leke
authors: R
authors: R
authors: Befidi-Mengue
authors: M
authors: M
authors: Tsafack
authors: D
authors: D
authors: Bomba-Nkolo
authors: L
authors: L
authors: Manga
authors: V
authors: V
authors: Tchinda
authors: E
authors: E
authors: Njeungue
authors: S
authors: S
authors: Kouontchou
authors: J
authors: J
authors: Fogako
authors: P
authors: P
authors: Nyonglema
authors: L T
authors: LT
authors: Harun
authors: R
authors: R
authors: Djokam
authors: G
authors: G
authors: Sama
authors: A
authors: A
authors: Eno
authors: R
authors: R
authors: Megnekou
authors: S
authors: S
authors: Metenou
authors: L
authors: L
authors: Ndountse
authors: A
authors: A
authors: Same-Ekobo
authors: G
authors: G
authors: Alake
authors: J
authors: J
authors: Meli
authors: J
authors: J
authors: Ngu
authors: F
authors: F
authors: Tietche
authors: J
authors: J
authors: Lohoue
authors: J L
authors: JL
authors: Mvondo
authors: E
authors: E
authors: Wansi
authors: R
authors: R
authors: Leke
authors: A
authors: A
authors: Folefack
authors: J
authors: J
authors: Bigoga
authors: C
authors: C
authors: Bomba-Nkolo
authors: V
authors: V
authors: Titanji
authors: A
authors: A
authors: Walker-Abbey
authors: M A
authors: MA
authors: Hickey
authors: A H
authors: AH
authors: Johnson
authors: D W
authors: DW
authors: Taylor
authors: L
authors: L
authors: Ndoutse
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000818:Animals; D000852:Anopheles / Q000145:classification / Q000469:parasitology*; D002163:Cameroon / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004199:Disease Vectors; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008137:Longitudinal Studies; D016778:Malaria, Falciparum / Q000453:epidemiology* / Q000276:immunology* / Q000635:transmission; D008297:Male; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000276:immunology / Q000302:isolation & purification* / Q000469:parasitology; D015995:Prevalence; D012621:Seasons