title: Parallel-stranded hairpins containing 8-aminopurines. Novel efficient probes for triple-helix formation.
abstract: We describe novel oligomers with a greater propensity to form triplexes than oligomers containing only natural bases. They consist of a polypyrimidine sequence linked head-to-head with a polypurine sequence carrying one or several 8-aminoadenine or 8-aminoguanines. The presence of 8-aminopurines also stabilised the parallel-stranded duplex structure.
authors: Cygene Spain S.L., Parc Científic de Barcelona, Baldiri i Reixac, 10-12, E-08028, Barcelona, Spain.
authors: A
authors: A
authors: Aviñó
authors: J C
authors: JC
authors: Morales
authors: M
authors: M
authors: Frieden
authors: B G
authors: BG
authors: de la Torre
authors: R G
authors: RG
authors: García
authors: E
authors: E
authors: Cubero
authors: F J
authors: FJ
authors: Luque
authors: M
authors: M
authors: Orozco
authors: F
authors: F
authors: Azorín
authors: R
authors: R
authors: Eritja
mesh_terms: D001483:Base Sequence; D015342:DNA Probes; D011687:Purines / Q000737:chemistry*
chemical_list: D015342:DNA Probes; D011687:Purines