Hydrolyzable tannins, the active constituents of three Greek Cytinus taxa against several tumor cell lines.
Hydrolyzable tannins were found to be the active cytotoxic constituents of three Greek Cytinus taxa: Cytinus ruber, Cytinus hypocistis subsp. hypocistis and Cytinus hypocistis subsp. orientalis. The cytotoxic activity was evaluated against a broad spectrum of cancer cell lines. The structure of the active compounds was investigated with NMR and electrospray-MS/MS techniques.
Magiatis
P
P
Department of Pharmacy, University of Athens, Greece.
Pratsinis
H
H
Kalpoutzakis
E
E
Konstantinidou
A
A
Davaris
P
P
Skaltsounis
A L
AL
D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry* / Q000145:classification; D013058:Mass Spectrometry; D013045:Species Specificity; D013634:Tannins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D013634:Tannins