title: Accurate assessment of patient effective radiation dose and associated detriment risk from radiofrequency catheter ablation procedures.
abstract: BACKGROUND
  Radiofrequency (RF) cardiac catheter ablation procedures may require extended fluoroscopic exposure resulting in elevated radiation risk. The aim of the present study was to accurately establish RF ablation radiation risk levels and to provide means for accurate patient risk estimation from studies performed in any electrophysiology laboratory.
  
  
  RESULTS
  Fluoroscopy required during cardiac ablation was classified into 4 types identified by beam orientation and irradiated tissue: (1) posteroanterior exposure during catheter advancing from the groin to the heart, (2) posteroanterior heart exposure, (3) left anterior oblique heart exposure, and (4) right anterior oblique heart exposure. The duration of each exposure was monitored in 24 patients undergoing RF cardiac ablation. Dose per minute of fluoroscopy was measured at 15 organs/tissues for each projection with the use of anthropomorphic phantom and thermoluminescence dosimetry. The effective dose rate was 219, 144, 136, and 112 mu/min for groin-to-heart posteroanterior, posteroanterior, left anterior oblique, and right anterior oblique exposure, respectively. A typical ablation procedure results in a total effective dose of 8.3 mSv per hour of fluoroscopy. The average excess of fatal cancers was estimated to be 650 and 480 per million patients undergoing RF ablation requiring 1 hour of fluoroscopy for US and UK populations, respectively. The average risk for genetic defects was determined to be 1 per million births.
  
  
  CONCLUSIONS
  Radiation risk from RF cardiac ablation is moderate compared with other complications, but it may highly exceed radiation risk from common radiological procedures. Efforts should be made toward minimization of patient radiation risk from RF ablation procedures.
authors: University of Crete, Faculty of Medicine, Iraklion, Crete, Greece.
authors: K
authors: K
authors: Perisinakis
authors: J
authors: J
authors: Damilakis
authors: N
authors: N
authors: Theocharopoulos
authors: E
authors: E
authors: Manios
authors: P
authors: P
authors: Vardas
authors: N
authors: N
authors: Gourtsoyiannis
mesh_terms: D000328:Adult; D000367:Age Factors; D002386:Cataract / Q000517:prevention & control; D017115:Catheter Ablation; D005260:Female; D005471:Fluoroscopy / Q000009:adverse effects / Q000145:classification / Q000592:standards*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control*; D011855:Radiodermatitis / Q000517:prevention & control; D011874:Radiometry / Q000592:standards*; D018570:Risk Assessment; D012737:Sex Factors; D013617:Tachycardia, Supraventricular / Q000601:surgery*; D013997:Time Factors; D006113:United Kingdom; D014481:United States