title: Comparison of power Doppler and velocimetry in predicting outcome of high-risk pregnancy.
abstract: OBJECTIVE
  Prospectively evaluate semi-quantitative computer analysis of power Doppler (PD) signals in the placenta, tetal brain, lung, liver, kidney and spleen in high-risk pregnancies in relationship to perinatal outcome and also to compare tissue blood flow in the fetal brain and placenta with Doppler velocimetry.
  
  
  METHODS
  PD signals were recorded in 180 high-risk pregnancies between 27 and 41 weeks of gestation. Images from PD angiographic scans were transmitted for computer analysis of pixel intensity. Mean flow signal intensity was recorded for each organ. The PD brain/lung ratio was calculated. The PD results were plotted on reference values and related to perinatal outcome. Middle cerebral (MCA), umbilical (UA) and uterine artery (Ut. A) velocimetry was also performed.
  
  
  RESULTS
  High-risk pregnancies displayed lower PD signal intensity from the placenta, fetal lung, liver and kidney as compared to normals. However, the brain and spleen signals showed higher intensities suggesting increased tissue perfusion. PD signals from the fetal brain, lung, placenta and PD brain/lung ratio were correlated with perinatal outcome. The PD signal intensity from the fetal liver, kidney and spleen showed poor correlation with perinatal outcome. Fetal brain tissue blood flow showed better correlation with the outcome than MCA velocimetry. Placental tissue blood flow results were similar in predicting outcome to those obtained by means of UA and Ut. A velocimetry.
  
  
  CONCLUSIONS
  In comparison with conventional Doppler velocimetry, computer analysis of PD signals, give similar results in the prediction of adverse perinatal outcome.
authors: Department of Perinatology and Gynecology, University School of Medical Sciences, Poznan, Poland. dubiel@sylaba.poznan.pl
authors: M
authors: M
authors: Dubiel
authors: A
authors: A
authors: Dobek
authors: G
authors: G
authors: Breborowicz
authors: K
authors: K
authors: Marsal
authors: S
authors: S
authors: Gudmundsson
mesh_terms: D001783:Blood Flow Velocity; D005260:Female; D005333:Fetus / Q000502:physiology; D006801:Humans; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D010920:Placenta / Q000098:blood supply; D011247:Pregnancy; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk; D011673:Pulsatile Flow; D012039:Regional Blood Flow; D012212:Rheology; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000000981:diagnostic imaging; D014599:Uterus / Q000098:blood supply