Enantioselective formal total synthesis of (-)-dysidiolide.
[reaction: see text] An enantioselective formal total synthesis of the sesterterpene (-)-dysidiolide 1 beginning with an intermolecular Diels-Alder reaction of the allene ester 3 and the silyloxydiene 10 is reported.
Jung
M E
ME
Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, USA. jung@chem.ucla.edu
Nishimura
N
N
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D000466:Alkadienes / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D008968:Molecular Conformation; D054830:Sesterterpenes; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry
D000466:Alkadienes; D000475:Alkenes; D004952:Esters; D054830:Sesterterpenes; D013729:Terpenes; C025947:propadiene; C121906:dysidiolide; D015107:4-Butyrolactone