Neurotransmitter receptor trafficking and the regulation of synaptic strength.
Modulation of the strength of synapses is thought to be one of the mechanisms that underlies learning and memory and is also likely to be important in processes of neuropathology and drug tolerance. This review focuses on the emerging role of postsynaptic neurotransmitter receptor trafficking as an essential mechanism underlying the dynamic regulation of synaptic strength.
Kittler
J T
JT
Medical Research Council Laboratory of Molecular Cell Biology and UCL Department of Pharmacology, University College London, London WC1E 6BT, UK.
Moss
S J
SJ
D000818:Animals; D006706:Homeostasis; D006801:Humans; D008959:Models, Neurological; D009473:Neuronal Plasticity; D017981:Receptors, Neurotransmitter / Q000737:chemistry / Q000502:physiology*; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission
D017981:Receptors, Neurotransmitter