title: Bidentatoside I, a new triterpene saponin from Achyranthes bidentata.
abstract: Bidentatoside I (1) is a new triterpene saponin bearing an unusual dioxopropionic acid unit, isolated from the roots of Achyranthes bidentata. Structural elucidation was performed mainly by chemical and homo- and heteronuclear 2D NMR techniques. This compound did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.
authors: Laboratoire de Pharmacognosie, Unité MIB, J E 2244, Faculté de Pharmacie, Université de Bourgogne, 7 Bd. Jeanne D'Arc, BP 87900, 21079 Dijon, France.
authors: A C
authors: AC
authors: Mitaine-Offer
authors: A
authors: A
authors: Marouf
authors: C
authors: C
authors: Pizza
authors: T C
authors: TC
authors: Khanh
authors: B
authors: B
authors: Chauffert
authors: M A
authors: MA
authors: Lacaille-Dubois
mesh_terms: D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D003110:Colonic Neoplasms / Q000188:drug therapy; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D008956:Models, Chemical; D012503:Saponins / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D012503:Saponins; D014315:Triterpenes; C433584:bidentatoside I