title: Long-term histologic features of synthetic chordal replacement for mitral valve repair: a case report.
abstract: Expanded polytetrafluoroethylene (e-PTFE) sutures have been used with increasing frequency to replace chordae tendineae in mitral valves prolapsing because of myxoid change. A case is reported where fibrosis and calcification of the endocardial overgrowth covering the synthetic chordae led to severe mitral regurgitation 7 years after plastic repair and required mechanical prosthetic valve implantation.
authors: Department of Experimental Medicine and Pathology, "La Sapienza" University, Rome, Italy.
authors: C R
authors: CR
authors: di Gioia
authors: G
authors: G
authors: Brancaccio
authors: R
authors: R
authors: Sinatra
authors: P
authors: P
authors: Gallo
mesh_terms: D002114:Calcinosis / Q000473:pathology; D006348:Cardiac Surgical Procedures; D002815:Chordae Tendineae / Q000473:pathology / Q000601:surgery*; D005355:Fibrosis / Q000473:pathology; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000473:pathology / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000473:pathology; D008945:Mitral Valve Prolapse / Q000473:pathology / Q000601:surgery*; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D012086:Reoperation; D013537:Sutures
chemical_list: D011138:Polytetrafluoroethylene