title: Pattern formation in the lateral line of zebrafish.
abstract: The lateral line of fish and amphibians is a sensory system that comprises a number of individual sense organs, the neuromasts, arranged in a defined pattern on the surface of the body. A conspicuous part of the system is a line of organs that extends along each flank (and which gave the system its name). At the end of zebrafish embryogenesis, this line comprises 7-8 neuromasts regularly spaced between the ear and the tip of the tail. The neuromasts are deposited by a migrating primordium that originates from the otic region. Here, we follow the development of this pattern and show that heterogeneities within the migrating primordium prefigure neuromast formation.
authors: Laboratoire de Neurogénétique, INSERM E-0012, Université Montpellier II, cc103 Place Eugène Bataillon, F-34095 Cedex 5, Montpellier, France.
authors: N
authors: N
authors: Gompel
authors: N
authors: N
authors: Cubedo
authors: C
authors: C
authors: Thisse
authors: B
authors: B
authors: Thisse
authors: C
authors: C
authors: Dambly-Chaudière
authors: A
authors: A
authors: Ghysen
mesh_terms: D000818:Animals; D019070:Cell Lineage; D002465:Cell Movement; D002467:Cell Nucleus / Q000378:metabolism; D003911:Dextrans / Q000494:pharmacology; D019793:Fluorescein / Q000494:pharmacology; D005456:Fluorescent Dyes / Q000494:pharmacology; D018507:Gene Expression Regulation, Developmental; D006198:Hair Cells, Auditory / Q000378:metabolism; D017403:In Situ Hybridization; D018715:Microscopy, Video; D008938:Mitosis; D009474:Neurons / Q000502:physiology*; D013997:Time Factors; D014466:Ultraviolet Rays; D015027:Zebrafish
chemical_list: D003911:Dextrans; D005456:Fluorescent Dyes; D019793:Fluorescein