Lupus flare associated with growth hormone.
This case illustrates a young man with an 11 y history of systemic lupus erythematosus who developed lupus flare after a 9-month use of growth hormone (GH) for the treatment of growth retardation. The course of disease was improving after GH cessation and treatment with high dose corticosteroids and intravenous cyclophosphamide pulse therapy.
Bae
Y S
YS
Department of Internal Medicine, Hanyang University College of Medicine and the Hospital for Rheumatic Diseases, Seoul, Korea.
Bae
S C
SC
Lee
S W
SW
Yoo
D H
DH
Kim
T Y
TY
Kim
S Y
SY
D000328:Adult; D003520:Cyclophosphamide / Q000008:administration & dosage; D005938:Glucocorticoids / Q000008:administration & dosage; D006130:Growth Disorders / Q000188:drug therapy* / Q000209:etiology; D019382:Human Growth Hormone / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy*; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D019382:Human Growth Hormone; D003520:Cyclophosphamide; D011239:Prednisolone