title: On the transformation behaviour, mechanical properties and biocompatibility of two niti-based shape memory alloys: NiTi42 and NiTi42Cu7.
abstract: The transformation behaviour, mechanical properties and cytotoxicity of a binary NiTi42 and a ternary NiTi42Cu7 alloy have been investigated. The transformation temperatures were determined via differential scanning calorimetry, the mechanical properties have been investigated in 3-point bending tests in the temperature range between 6 and 60 degrees C. The cytotoxicity tests were performed on both alloys in cultured epithelial cells from human gingiva. The cytotoxicity investigations included both MTT tests and morphological observations. It is shown that although the ternary alloy is characterised by a narrower hysteresis and superior mechanical properties, including fatigue resistance, its cytotoxicity is higher than that of the binary alloy. This is thought to arise from the release of copper ions in the medium, which upon atomic absorption spectroscopy measurements amount to approximately 2.8 microg cm(-2) for an incubation period of 7 days.
authors: Materials Testing and Joining, University of Applied Sciences, Fachhochschule Kiel, Germany. mohammed.es-souni@fh-kiel.de
authors: M
authors: M
authors: Es-Souni
authors: M
authors: M
authors: Es-Souni
authors: H F
authors: HF
authors: Brandies
mesh_terms: D000497:Alloys; D001672:Biocompatible Materials; D002478:Cells, Cultured; D003035:Cobalt / Q000737:chemistry*; D004396:Coloring Agents / Q000494:pharmacology; D004847:Epithelial Cells / Q000166:cytology; D005881:Gingiva / Q000166:cytology; D007150:Immunohistochemistry; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D009532:Nickel / Q000737:chemistry*; D013314:Stress, Mechanical; D013696:Temperature; D013778:Tetrazolium Salts / Q000494:pharmacology; D013816:Thermodynamics; D013844:Thiazoles / Q000494:pharmacology; D014025:Titanium / Q000737:chemistry*
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D004396:Coloring Agents; D013778:Tetrazolium Salts; D013844:Thiazoles; C093972:titanium-nickel-cobalt alloy; D003035:Cobalt; D009532:Nickel; D014025:Titanium; C022616:thiazolyl blue