m-Iodobenzoic acid complexes with selected metals: molecular structure and antimicrobial activity.
Complexes of lithium, sodium, potassium, rubidium, cesium, magnesium, calcium, manganese, and zinc with m-iodobenzoic acid were studied. The FT-IR and FT-Raman spectra of the mentioned compounds in the solid state and water solutions were recorded and analyzed. Principal component analysis (PCA) was performed on the wavenumbers of selected bands (eight bands) occurring in the vibrational spectra. The numbers obtained as a result of this procedure characterize the electronic properties of the molecule of each complex. The antimicrobial activity of the studied compounds against selected bacteria (Escherichia coli and Bacillus subtilis) and yeast (Saccharomyces cerevisiae and Hansenula anomala) was estimated. The relationship between the chemical properties (as characterized by PCA of the IR spectra) and antimicrobial properties of the compounds was examined, and a good correlation between the two factors was found.
Koczoń
P
P
Department of General Chemistry, Warsaw Agricultural University, Rakowiecka 26/30, 02-528 Warsaw, Poland. koczon@delta.sggw.waw.pl
Lewandowski
W
W
Lipińska
E
E
Sobczak
E
E
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D019817:Benzoic Acid; D004926:Escherichia coli / Q000187:drug effects; D007463:Iodobenzoates / Q000494:pharmacology*; D008670:Metals; D015394:Molecular Structure; D010843:Pichia / Q000187:drug effects; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013059:Spectrum Analysis, Raman / Q000379:methods
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D007463:Iodobenzoates; D008670:Metals; D019817:Benzoic Acid