title: In vitro effects of photodynamic therapy on Aspergillus fumigatus.
abstract: Photodynamic therapy is a technique for killing cells with visible light after pretreatment with a photosensitizing agent. We demonstrated significant in vitro fungicidal activity against Aspergillus fumigatus of the photosensitizer Green 2W, activated with 630 nm light. This effect was both inoculum- and light dose-dependent. At a Green 2W concentration of 31.5 mg/L, there was complete killing of 2.7 x 10(1) cfu/mL with a light dose of 110 J/cm(2) and up to 2.7 x 10(6) cfu/mL with a light dose of 385 J/cm(2).
authors: Department of Surgery, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. joseph.friedberg@mail.TJU.edu
authors: J S
authors: JS
authors: Friedberg
authors: C
authors: C
authors: Skema
authors: E D
authors: ED
authors: Baum
authors: J
authors: J
authors: Burdick
authors: S A
authors: SA
authors: Vinogradov
authors: D F
authors: DF
authors: Wilson
authors: A D
authors: AD
authors: Horan
authors: I
authors: I
authors: Nachamkin
mesh_terms: D001232:Aspergillus fumigatus / Q000187:drug effects*; D010778:Photochemotherapy