New glycosphingolipid containing an unusual sphingoid base from the basidiomycete Polyporus ellisii.
A new 9-methyl-sphinga-4,8-dienine-containing glucocerebroside (1), together with two additional known analogs, cerebrosides B and D, was isolated from the chloroform-soluble lipid fraction of the ethanol and chloroform/methanol extract of the fruiting bodies of the basidiomycete Polyporus ellisii Berk. and characterized. The structure and relative stereochemistry of the new compound were identified as (2S,3R,4E,8E-1-(beta-D-glucopyranosyl)-3-hydroxy-2-[(R)-2'-hydroxyheptadecanoyl]amino-9-methyl-4,8-octadecadiene by means of spectroscopic (1H,13C, and two-dimensional nuclear magnetic resonance; mass spectrometry) and chemical methods.
Gao
J M
JM
Department of Phytochemisty, Kunming Institute of Botany, Chinese Academy of Sciences, People's Republic of China.
Hu
L
L
Dong
Z J
ZJ
Liu
J K
JK
D000473:Alkanes / Q000737:chemistry* / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D006028:Glycosphingolipids / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D011124:Polyporaceae / Q000737:chemistry*
C439223:1-(glucopyranosyl)-3-hydroxy-2-(2'-hydroxyheptadecanoyl)amino-9-methyl-4,8-octadecadiene; D000473:Alkanes; D006028:Glycosphingolipids