[Fetal lung maturity in biamniotic twin pregnancy].
OBJECTIVE
To assess the need to perform amniocentesis for the evaluation of fetal lung maturity (FLM) in both amniotic sacs of twin pregnancies.


METHODS
A retrospective study. We considered 33 twin biamniotic pregnancies, delivering within 1 week from amniocentesis. FLM testing was performed by planimetric lecithin/sphingomyelin ratio (L/S), and lamellar bodies count (LB) according to our methodology.


RESULTS
A strong correlation was found between L/S (p < 0.001, r = 0.59) and LB (p < 0.001, r = 0.69) values between smaller and larger twins. No significant regression was found between differences of L/S and LB among both amniotic sacs against gestational age. When stratifying FLM values < 34 and > 34 wks' gestation, again no difference was found in mean difference of L/S and LB before and after 34 wks.


CONCLUSIONS
FLM should not be assessed in both amniotic sacs at any gestational age independent of weight and/or sex of the conceptus.
Piazze
J
J
2o Istituto Clinica Ostetrica e Ginecologica, Università La Sapienza di Roma, Italia. jjpiazze2000@hotmail.com
Anceschi
M
M
Marini
T
T
Cerekja
A
A
Amici
F
F
Vitali
S
S
Pietro
C
C
Terracina
G M
GM
Kashami
A
A
Cosmi
E V
EV
D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D008168:Lung / Q000196:embryology*; D011247:Pregnancy; D012189:Retrospective Studies; D014429:Twins, Dizygotic