title: Tissue expansion using osmotically active hydrogel systems for direct closure of the donor defect of the radial forearm flap.
abstract: Although widely used, the radial forearm flap has been criticized for the poor quality of its donor site. Attempts to avoid donor-site problems have concentrated on the elaboration of the split-thickness and full-thickness skin graft methods of reconstruction. Skin grafts frequently fail over the flexor carpi radialis tendon, leading to chronic skin breakdown or, at best, tendon adhesion. Tissue expansion appears to be a good alternative that allows the use of local tissues to ultimately improve the forearm donor-site appearance. To avoid the disadvantages of traditional silicone balloon expanders (such as pressure peaks, infection, the valve at a distance from the expander, postoperative fillings), an osmotically active system was used. In an 18-month prospective study, 10 osmotically active hydrogel tissue expanders were placed on the forearms of 10 patients. The radial forearm flap was performed for intraoral reconstruction after surgical resection of oral cavity malignancies. The study showed that, in nine out of 10 patients, the expanded skin achieved was sufficient to cover the donor site after raising the forearm flap. Additionally, the expansion-related swelling pressure was well tolerated by the patients, the cosmetic results were very satisfactory, and the incidence of complications was very low. By using osmotically active hydrogel tissue expanders, there is no postoperative filling and no risk of complications arising from defective balloon expanders, filling valves, or missing ports.
authors: Department of Oral and Maxillofacial Surgery, Friedrich-Wilhelm University, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany. s.berge@uni-bonn.de
authors: S J
authors: SJ
authors: Bergé
authors: K G
authors: KG
authors: Wiese
authors: J J
authors: JJ
authors: von Lindern
authors: B
authors: B
authors: Niederhagen
authors: T
authors: T
authors: Appel
authors: R H
authors: RH
authors: Reich
mesh_terms: D000328:Adult; D000368:Aged; D005542:Forearm / Q000601:surgery*; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000601:surgery; D009995:Osmosis; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods*; D013524:Surgical Flaps; D015626:Tissue Expansion / Q000009:adverse effects / Q000379:methods*
chemical_list: D020136:Hydrogel, Polyethylene Glycol Dimethacrylate