[Chronic obstructive lung diseases in patients with ischemic heart disease: a 15-year study].
OBJECTIVE
To characterize acquired chronic obstructive pulmonary diseases (COPD) in patients with ischemic heart disease (IHD).


METHODS
Monitoring of external respiration function (ERF) was performed for 15 years in 1552 IHD patients on combined drug treatment.


RESULTS
The 15-year follow-up has revealed that IHD patients treated with beta-blockers develop pathological changes in respiration pattern manifesting primarily with dyspnea, obstructive and mixed ventilatory disorders, syndrome of early expiratory obstruction in affected small airways due to subnormal lung elasticity, defective diffuse function, signs of terminal respiratory failure.


CONCLUSIONS
IHD patients taking drugs need monitoring of ERF. Optimal treatment consists in early diagnosis of IHD and COPD, adequate combined therapy with beta-blockers and bronchodilating drugs.
Kozlova
L I
LI
Buzunov
R V
RV
Chuchalin
A G
AG
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D000368:Aged; D001696:Biomechanical Phenomena; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000503:physiopathology; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications* / Q000175:diagnosis; D012119:Respiration; D012129:Respiratory Function Tests; D012307:Risk Factors; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D001993:Bronchodilator Agents