title: Inactivation of monoamine oxidase B by 1-phenylcyclopropylamine: mass spectral evidence for the flavin adduct.
abstract: Incubation of 1-phenylcyclopropylamine with bovine liver MAO (MAO B), followed by complete enzymatic digestion to single amino acid residues and subsequent analysis by on-line liquid chromatography-electrospray ionization mass spectrometry, was used to investigate the resulting flavin adduct structure.
authors: Department of Chemistry and Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, 60208-3113, Evanston, IL, USA.
authors: D J
authors: DJ
authors: Mitchell
authors: D
authors: D
authors: Nikolic
authors: R B
authors: RB
authors: van Breemen
authors: R B
authors: RB
authors: Silverman
mesh_terms: D000818:Animals; D002417:Cattle; D002853:Chromatography, Liquid / Q000379:methods; D003521:Cyclopropanes / Q000737:chemistry / Q000494:pharmacology*; D005415:Flavins / Q000737:chemistry*; D008995:Monoamine Oxidase / Q000187:drug effects*; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods
chemical_list: D003521:Cyclopropanes; D005415:Flavins; D008996:Monoamine Oxidase Inhibitors; C045293:1-phenylcyclopropylamine; D008995:Monoamine Oxidase