title: [Anesthesia in extreme obesity].
abstract: BACKGROUND
  Approximately 1-2% of all anesthetized patients are morbidly obese (body mass index > 35 kg/m2). The perioperative mortality is significantly elevated (up to 20%) compared with lean patients. Morbidly obese patients are at high risk for cardiopulmonary dysfunction. Difficult airway management is reported in 13-20% of obese patients. Hypoxia is often observed due to faster desaturation during induction of anesthesia. After surgery, patients are endangered by a high incidence of obstructive sleep apnea syndrome (50%), pulmonary atelectasis (5%) and acute pulmonary embolism (5-12%).
  
  
  METHODS
  Individualized perioperative management is required based on preoperative history and physical examination. Modern anesthetic drugs (desfluran, sevoflurane or propofol, and remifentanil, respectively) allow rapid recovery and early postoperative mobilization. Adequate monitoring, e.g. by an intraarterial blood pressure monitoring and repetitive blood gas analyses, improves patient safety prior the onset of complications.
  
  
  METHODS
  Postoperative admission on an intensive care unit of morbidly obese patients is based upon concomitant diseases and surgical requirements. The main reason for admission is an inadequate pulmonary gas exchange. This interdisciplinary approach will reduce the risk of anesthesia and avoid complications in morbidly obese patients.
authors: Klinik für Anästhesiologie und operative Intensivmedizin, Charité, Campus Mitte, Humboldt-Universität zu Berlin. torsten.schroeder@charite.de
authors: T
authors: T
authors: Schröder
authors: M
authors: M
authors: Nolte
authors: W J
authors: WJ
authors: Kox
authors: C
authors: C
authors: Spies
mesh_terms: D000768:Anesthesia, General; D002423:Cause of Death; D006801:Humans; D007431:Intraoperative Complications / Q000401:mortality; D016343:Monitoring, Intraoperative; D009203:Myocardial Infarction / Q000401:mortality; D009767:Obesity, Morbid / Q000401:mortality / Q000503:physiopathology*; D011183:Postoperative Complications / Q000401:mortality; D012307:Risk Factors