title: Randomised clinical trials: a source of ethical dilemmas.
abstract: Advances in medicine are closely linked to clinical research, but certain study procedures may be in conflict with the fundamental principles of ethics and codes of conduct in medicine. Following an analysis of two studies involving treatments for acute myocardial infarction (AMI), the admissibility of continuing a study was questioned after the initial results for two types of treatment showed that one was significantly better than the other. Also considered doubtful was the information provided to patients with the object of obtaining their informed consent.
authors: University of Valencia, Spain.
authors: F
authors: F
authors: Verdú-Pascual
authors: A
authors: A
authors: Castelló-Ponce
mesh_terms: D017130:Angioplasty / Q000401:mortality; D003325:Coronary Care Units / Q000592:standards; D004992:Ethics, Medical; D017052:Hospital Mortality; D006801:Humans; D007258:Informed Consent; D009203:Myocardial Infarction / Q000401:mortality* / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic / Q000592:standards*; D015912:Thrombolytic Therapy / Q000401:mortality; D016896:Treatment Outcome