title: MR imaging of intrahepatic cholangiocarcinoma: use of ferumoxides for lesion localization and extension.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the use of ferumoxides in the visualization and localization of intrahepatic cholangiocarcinoma.
  
  
  CONCLUSIONS
  The contrast-to-noise ratio of cholangiocarcinoma compared with that of the adjacent liver significantly (p < 0.03) improves after ferumoxides administration. Ferumoxides-enhanced MR imaging is a useful technique for the visualization and localization of intrahepatic cholangiocarcinoma.
authors: Department of Radiology, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 N. Wolfe St., Baltimore, MD 21287, USA.
authors: H J
authors: HJ
authors: Braga
authors: K
authors: K
authors: Imam
authors: D A
authors: DA
authors: Bluemke
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000473:pathology*; D003287:Contrast Media; D003911:Dextrans; D005260:Female; D052203:Ferrosoferric Oxide; D006801:Humans; D007501:Iron; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles; D008297:Male; D008875:Middle Aged; D010087:Oxides
chemical_list: D003287:Contrast Media; D003911:Dextrans; D058185:Magnetite Nanoparticles; D010087:Oxides; D007501:Iron; C065507:ferumoxides; D052203:Ferrosoferric Oxide