title: A structured review of quality of life instruments for head and neck cancer patients.
abstract: BACKGROUND
  Quality of life (QOL) is an important treatment outcome for head and neck cancer. Our purpose was to critically review published disease-specific QOL instruments.
  
  
  METHODS
  Medline and Cancerlit were searched from 1966-1999. Eight disease-specific QOL instruments were identified, described, and appraised for development, sensibility, reliability, validity and responsiveness to change.
  
  
  RESULTS
  Several of the available instruments have been well-developed and characterized. No one instrument is ideal for all purposes. When selecting a disease-specific QOL instrument for head and neck cancer patients, careful consideration must be given to disease subsite, treatment, timing of assessment, clinical setting, study purpose and research question.
  
  
  CONCLUSIONS
  Validation of QOL instruments is an ongoing process. Direct comparisons of different instruments may help to establish the most appropriate questionnaire for each situation. Efforts should be focused on the evaluation of existing instruments, rather than the development of new questionnaires.
authors: Department of Radiation Oncology, Princess Margaret Hospital/University Health Network, University of Toronto, Ontario, Canada.
authors: J
authors: J
authors: Ringash
authors: A
authors: A
authors: Bezjak
mesh_terms: D000222:Adaptation, Physiological; D000223:Adaptation, Psychological; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy*; D006801:Humans; D008297:Male; D010358:Patient Participation; D011379:Prognosis; D011788:Quality of Life; D012720:Severity of Illness Index; D012803:Sick Role; D011795:Surveys and Questionnaires