title: An unusual form of generalized granuloma annulare in a patient with insulin-dependent diabetes mellitus.
abstract: The generalized form of granuloma annulare may be associated with systemic disorders, including diabetes mellitus. We describe here an unusual form of generalized granuloma annulare in a patient with complicated insulin-dependent diabetes mellitus. The cutaneous eruption had been present for decades as non-pruritic, persistent, violet-brown patches with raised edges. There were flexion deformities of the small joints of the hands and feet associated with thickening of the skin over dorsa of the fingers. The patient is currently on isotretinoin therapy, with partial resolution of lesions at 3 months follow-up.
authors: Hacettepe University Faculty of Medicine, Ankara, Turkey. emelerkek@hotmail.com
authors: E
authors: E
authors: Erkek
authors: A
authors: A
authors: Karaduman
authors: G
authors: G
authors: Bükülmez
authors: N
authors: N
authors: Sentürk
authors: O
authors: O
authors: Ozkaya
mesh_terms: D001132:Arm; D001707:Biopsy, Needle; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis; D005500:Follow-Up Studies; D016460:Granuloma Annulare / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage; D007866:Leg; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012720:Severity of Illness Index; D013909:Thorax
chemical_list: D015474:Isotretinoin