Peripheral nonulcerative keratitis as a presenting sign of microscopic polyangiitis.
OBJECTIVE
To report a 16-year-old woman who had peripheral keratitis as a presenting sign of microscopic polyangiitis (MPA), which rapidly progressed to acute renal failure.


METHODS
Case report.


RESULTS
The patient's vasculitis was diagnosed by renal biopsy, which was evaluated with histologic, immunofluorescence, and electron microscopy. The diagnosis was confirmed by laboratory study, which showed a positive antimyeloperoxidase antibody.


CONCLUSIONS
MPA may rarely present with ocular findings and should be considered in the differential diagnosis when a patient has peripheral keratitis.
Darlington
J K
JK
Department of Ophthalmology, University of California, Davis, California, USA.
Mannis
M J
MJ
Segal
W A
WA
Feiz
V
V
Klug
D E
DE
D058186:Acute Kidney Injury / Q000175:diagnosis; D000293:Adolescent; D001323:Autoantibodies / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007634:Keratitis / Q000175:diagnosis*; D009195:Peroxidase / Q000276:immunology; D014657:Vasculitis / Q000175:diagnosis*
D001323:Autoantibodies; D009195:Peroxidase