title: Spongiadioxins A and B, two new polybrominated dibenzo-p-dioxins from an Australian marine sponge Dysidea dendyi.
abstract: Two new cytotoxic tetrabromodibenzo-p-dioxins, spongiadioxins A (1) and B (2), were isolated from an Australian marine sponge Dysidea dendyi. The structures of these compounds were established by 1D and 2D NMR spectroscopy, X-ray analysis of the methyl ether of spongiadioxin A (3), and synthesis of the methyl ether of spongiadioxin B (4) from diphenyl ether (9) isolated from Dysidea herbacea.
authors: Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, 690022 Vladivostok, Russia. utkinan@mail.ru
authors: N K
authors: NK
authors: Utkina
authors: V A
authors: VA
authors: Denisenko
authors: O V
authors: OV
authors: Scholokova
authors: M V
authors: MV
authors: Virovaya
authors: A V
authors: AV
authors: Gerasimenko
authors: D Y
authors: DY
authors: Popov
authors: V B
authors: VB
authors: Krasokhin
authors: A M
authors: AM
authors: Popov
mesh_terms: D000818:Animals; D001315:Australia; D004147:Dioxins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D008958:Models, Molecular; D011161:Porifera / Q000737:chemistry*
chemical_list: D004147:Dioxins; C433568:spongiadioxin A; C433569:spongiadioxin B