Effect of transplantation of embryonic nervous tissue on reorganization of interneuronal relationships after mechanical damage to sensorimotor cortex.
The effect of implanted embryonic nervous tissue on restoration of axonal connections in the cerebral cortex after mechanical injury was studied on albino rats using fluorescent lipophilic probe DiI (1,1'-dioctadecyl-3,3,3',3'-tetramethyl-indocarbocyanine perchlorate) and confocal laser scanning microscope. Implantation of embryonic tissue to damaged area promotes the growth of axons through the transplant to adjacent tissue. The damaged area is impenetrable for axons growing without implantation.
Ereniev
S I
SI
Department of Histology, Cytology, and Embryology, Omsk State Medical Academy.
Akulinin
V A
VA
Stepanov
S S
SS
Semchenko
V V
VV
Belichenko
P V
PV
D000818:Animals; D016332:Fetal Tissue Transplantation; D008297:Male; D009044:Motor Cortex / Q000473:pathology*; D009417:Nerve Tissue / Q000196:embryology / Q000637:transplantation*; D009474:Neurons / Q000166:cytology*; D051381:Rats; D013003:Somatosensory Cortex / Q000473:pathology*