The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes.
Polonsky
K S
KS
Department of Medicine and Cell Biology, Washington University School of Medicine, St. Louis, MO 63110, USA. polonsky@im.wustl.edu
Semenkovich
C F
CF
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003920:Diabetes Mellitus / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D000078790:Insulin Secretion; D007473:Ion Channels; D007515:Islets of Langerhans / Q000378:metabolism*; D026901:Membrane Transport Proteins; D051379:Mice; D008820:Mice, Obese; D008822:Mice, Transgenic; D024101:Mitochondrial Proteins; D009765:Obesity / Q000378:metabolism; D011506:Proteins / Q000235:genetics / Q000378:metabolism*; D014475:Uncoupling Agents / Q000378:metabolism; D000071246:Uncoupling Protein 2
D001786:Blood Glucose; D007328:Insulin; D007473:Ion Channels; D026901:Membrane Transport Proteins; D024101:Mitochondrial Proteins; D011506:Proteins; C000604389:UCP2 protein, human; C000604390:Ucp2 protein, mouse; D014475:Uncoupling Agents; D000071246:Uncoupling Protein 2; D000255:Adenosine Triphosphate; D005947:Glucose