Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart.
Gredilla
R
R
Department of Animal Biology-II (Animal Physiology), Faculty of Biology, Complutense University, Madrid 28040, Spain.
Sanz
A
A
Lopez-Torres
M
M
Barja
G
G
D000818:Animals; D002151:Calorimetry; D004272:DNA, Mitochondrial / Q000378:metabolism*; D005609:Free Radicals / Q000378:metabolism*; D006321:Heart / Q000502:physiology; D006861:Hydrogen Peroxide / Q000378:metabolism; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D018384:Oxidative Stress / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar
D004272:DNA, Mitochondrial; D005609:Free Radicals; D006861:Hydrogen Peroxide