Absence of BAT-26 instability in gastric intestinal metaplasia.
BAT-26 instability, a sensitive marker for the high-frequency microsatellite instability (MSI-H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI-H gastric cancer samples showed BAT-26 instability, as assessed using 12 dinucleotide microsatellite markers, BAT-26 instability was not found in the adjacent intestinal metaplastic mucosa in any of the samples.
Jin
Z
Z
Department of Pathology, Yamagata University School of Medicine, Yamagata, Japan.
Tamura
G
G
Satoh
M
M
Meguro
T
T
Miura
T
T
Hayashi
M
M
Osakabe
M
M
Ohmura
K
K
Ogata
S
S
Endoh
Y
Y
Motoyama
T
T
D005819:Genetic Markers; D006801:Humans; D007410:Intestinal Diseases / Q000235:genetics* / Q000473:pathology; D007413:Intestinal Mucosa / Q000473:pathology*; D008679:Metaplasia / Q000235:genetics / Q000473:pathology; D018895:Microsatellite Repeats / Q000235:genetics*; D011230:Precancerous Conditions / Q000235:genetics* / Q000473:pathology; D013274:Stomach Neoplasms / Q000235:genetics* / Q000473:pathology
D005819:Genetic Markers