Assessment of genetic variability of resistance to gastrointestinal nematode parasites in Creole goats in the humid tropics.
Goat production is widespread in the tropics. Goats are very susceptible to gastrointestinal nematode infection, but there is less evidence of their genetic resistance. Genetic resistance of Creole goats to gastrointestinal nematodes has been studied at Guadeloupe in the French West Indies since 1995. The objective of this research was to investigate genetic variation for resistance to gastrointestinal nematode infection, in order to introduce this trait into breeding schemes. Genetic variability was assessed within a Creole experimental flock. Forty-nine sire groups were characterized at weaning and 55 during fattening after weaning. Kids were naturally infected, mainly by Haemonchus contortus and Trichostrongylus colubriformis. Fecal egg counts were determined once at weaning and every 6 and 7 wk after drenching during fattening. Blood samples were collected every 7 wk during fattening for determination of packed cell volume. Live weights were recorded at weaning and at the beginning and middle of every infection period during fattening. Genetic parameters were estimated using the REML for multivariate animal models. The heritability estimate for transformed fecal egg count was 0.37+/-0.06 at weaning. During fattening, it increased from 0.14+/-0.05 at 4 mo to 0.33+/-0.06 at 10 mo. Heritabilities of packed cell volume ranged from 0.10 to 0.33. At weaning, maternal heritability of fecal egg count reached 0.26 and direct heritability 0.20. After 6 mo of age, maternal effects were found to be unimportant for fecal egg count and packed cell volume. Live weights presented significant genetic variability. Genetic relationships between fecal egg counts and live weight in infected pastures were never significant. Genetic correlations between packed cell volume and live weight decreased from 0.47 to 0.10 from weaning to 10 mo of age. These results demonstrated the feasibility of breeding for improved resistance to nematodes in Creole kids.
Mandonnet
N
N
Institut National de la Recherche Agronomique, Station de Recherches Zootechniques, Domaine Duclos, Guadeloupe, French West Indies. mandonne@antilles.inra.fr
Aumont
G
G
Fleury
J
J
Arquet
R
R
Varo
H
H
Gruner
L
L
Bouix
J
J
Khang
J V
JV
D000818:Animals; D001947:Breeding / Q000379:methods; D005243:Feces / Q000469:parasitology; D005260:Female; D005767:Gastrointestinal Diseases / Q000235:genetics / Q000276:immunology / Q000662:veterinary*; D014644:Genetic Variation; D015511:Goat Diseases / Q000235:genetics / Q000276:immunology*; D006041:Goats; D006813:Humidity; D007113:Immunity, Innate / Q000235:genetics; D008297:Male; D009349:Nematode Infections / Q000235:genetics / Q000276:immunology / Q000662:veterinary*; D010270:Parasite Egg Count / Q000662:veterinary; D014329:Tropical Climate