Enzymatic N-dealkylation of an N-cyclopropylamine: an unusual fate for the cyclopropyl group.
Shaffer
C L
CL
Department of Medicinal Chemistry University of Kansas, Lawrence, Kansas 66045-2506, USA.
Morton
M D
MD
Hanzlik
R P
RP
D000818:Animals; D003521:Cyclopropanes / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003640:Dealkylation; D006801:Humans; D008995:Monoamine Oxidase / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism*
D003521:Cyclopropanes; C067351:cyclopropylamine; D003577:Cytochrome P-450 Enzyme System; D010088:Oxidoreductases; D008995:Monoamine Oxidase