title: The respiratory burst response of surface-adhering leukocytes. A key to tissue engineering.
abstract: Biomaterials implanted into tissue will participate in the complex signalling between cells during wound healing. Recent studies have revealed that crucial cellular signalling pathways are regulated by the extra- and intracellular redox states and that reactive oxygen species function as intercellular signal molecules. Biomaterials have been shown to affect the respiratory burst response of surface-adhering leukocytes, thus interfering with major regulatory functions of cells also in surrounding tissues. The respiratory burst of surface-adhering leukocytes may thus be a key event in the understanding of biomaterial interaction with tissues, and the aim of this review is to highlight this field of research.
authors.affiliation: Department of Applied Cell Biology, Institute of Anatomy and Cell Biology, University of Göteborg, PO Box 420, SE-405 30, Göteborg, Sweden
authors.forename: H
authors.initials: H
authors.lastname: Nygren
authors.forename: M
authors.initials: M
authors.lastname: Broberg
authors.forename: C
authors.initials: C
authors.lastname: Eriksson
authors.forename: H
authors.initials: H
authors.lastname: Sahlin
authors.forename: N
authors.initials: N
authors.lastname: Yahyapour