title: Diastereomeric diterpenes from Coleus blumei.
abstract: The chloroform extract of the air-dried leaves of Coleus blumei afforded a mixture of diastereomers of a new abietane type diterpene whose structures were elucidated by extensive one and two dimensional (ID, 2D) NMR and mass spectrometry. Acetylation of the mixture afforded a single compound. Antimicrobial tests on the diterpene indicate that it is active against Bacillus subtilis, Pseudomonas aeruginosa and Candida albicans.
authors.affiliation: Chemistry Department, De La Salle University, Manila, Philippines. coscyr@mail.dlsu.edu.ph
authors.forename: C Y
authors.initials: CY
authors.lastname: Ragas
authors.forename: V F
authors.initials: VF
authors.lastname: Templora
authors.forename: J A
authors.initials: JA
authors.lastname: Rideout
mesh_terms: D000107:Acetylation; D001419:Bacteria / Q000187:drug effects; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D010679:Philippines; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004224:Diterpenes