title: Effects of inorganic and organic copper supplemented to first-calf cows on cow reproduction and calf health and performance.
abstract: Two experiments were conducted to determine whether the supplementation of Cu in the organic or inorganic form to 2-yr-old cows, before and after calving, affects reproduction rate, calf health and performance, passive transfer of immunoglobulin, or liver and serum Cu concentrations compared with unsupplemented controls. Cows (n = 75 in 1997; n = 120 in 1998) were randomly assigned by estimated calving date and body condition score to one of three treatments: 1) Control, control; 2) Inorganic, inorganic Cu supplement (200 mg Cu from CuSO4); 3) Organic, organic Cu supplement (100 mg Cu from AvailaCu). In 1998, a fourth treatment was added; 4) CU-ZN, organic Cu and Zn (400 mg Zn from AvailaZn in the Organic diet). Cows were fed a hay-based diet and individually fed supplements for approximately 45 d before and 60 d after calving (approximately January 15 to May 15 each year). Liver biopsies were obtained from cows before supplementation began, and from cows and calves at 10 and 30 d after calving. Blood samples were obtained from both cows and calves at calving, and colostrum samples were collected for IgG and mineral content. Cow liver Cu concentrations before supplementation began were 58 mg/kg in 1997 and 40 mg/kg (DM basis) in 1998. By 10 d after calving, liver Cu concentrations of Control cows had decreased (P < 0.05) to 24 mg/kg (Cu deficient) in both years, whereas liver Cu concentrations of Cu-supplemented cows increased (P < 0.05) in both years. Calf liver Cu concentrations at 10 d of age were similar (P > 0.10) for all treatment groups. No differences (P > 0.10) were found in colostrum Cu concentrations, or in calf health among treatments. No differences (P > 0.10) were found in cow BW change, calf serum Cu concentrations, calf weaning weights, or in cow 60-d pregnancy rates among treatments in either year. In 1998, cows in the Organic group had higher (P < 0.05) 30-d pregnancy rate than Control cows. Neither serum samples nor placental tissue were reliable indicators of Cu status in cows. Feeding supplemental Cu (either inorganic, organic, or organic with extra Zn) to cows with liver Cu concentrations of approximately 50 mg/kg before calving did not improve cow 60-d pregnancy rates or the health and performance of their calves when compared with unsupplemented cows.
authors.affiliation: Department of Animal Science, University of Nebraska, Lincoln 68583-0908, USA.
authors.forename: E L
authors.initials: EL
authors.lastname: Muehlenbein
authors.forename: D R
authors.initials: DR
authors.lastname: Brink
authors.forename: G H
authors.initials: GH
authors.lastname: Deutscher
authors.forename: M P
authors.initials: MP
authors.lastname: Carlson
authors.forename: A B
authors.initials: AB
authors.lastname: Johnson
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001835:Body Weight; D002417:Cattle / Q000502:physiology*; D003300:Copper / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D019587:Dietary Supplements; D005260:Female; D007116:Immunization, Passive / Q000662:veterinary; D007501:Iron; D008099:Liver / Q000378:metabolism; D008982:Molybdenum; D006109:Poaceae; D011247:Pregnancy; D018873:Pregnancy Rate; D012098:Reproduction / Q000187:drug effects*; D012621:Seasons
chemical_list: D003300:Copper; D008982:Molybdenum; D007501:Iron