title: Approach to high-resolution ex situ NMR spectroscopy.
abstract: Nuclear magnetic resonance (NMR) experiments are typically performed with samples immersed in a magnet shimmed to high homogeneity. However, there are many circumstances in which it is impractical or undesirable to insert objects or subjects into the bore of a high-field magnet. Here we present a methodology based on an adaptation of nutation echoes that provides resolved spectra in the presence of matched inhomogeneous static and radiofrequency fields, thereby opening the way to high-resolution ex situ NMR. The observation of chemical shifts is regained through the use of multiple-pulse sequences of correlated, composite z-rotation pulses, producing resolved NMR spectra of liquid samples.
authors.affiliation: Materials Sciences Division, Lawrence Berkeley National Laboratory and Department of Chemistry, University of California, Berkeley, CA 94720, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Meriles
authors.forename: D
authors.initials: D
authors.lastname: Sakellariou
authors.forename: H
authors.initials: H
authors.lastname: Heise
authors.forename: A J
authors.initials: AJ
authors.lastname: Moule
authors.forename: A
authors.initials: A
authors.lastname: Pines
mesh_terms: D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008280:Magnetics; D011522:Protons; D012399:Rotation; D012996:Solutions
chemical_list: D011522:Protons; D012996:Solutions