Intracellular signalling: sphingosine-1-phosphate branches out.
Recent studies indicate that sphingosine-1-phosphate - known to be an important signalling molecule in animal cells - is involved in Ca(2+)-dependent signalling in yeast and higher plants, raising the likelihood that it is a universal signalling molecule with a diverse range of functions in eukaryotes.
Brownlee
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Marine Biological Association, The Laboratory, Citadel Hill, PL1 2PB, Plymouth, UK. cbr@mba.ac.uk
D020013:Calcium Signaling; D008246:Lysophospholipids; D008954:Models, Biological; D010944:Plants / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D015398:Signal Transduction; D013110:Sphingosine / Q000031:analogs & derivatives / Q000502:physiology*
D008246:Lysophospholipids; C060506:sphingosine 1-phosphate; D013110:Sphingosine