title: The clinical profile of childhood optic neuritis.
abstract: OBJECTIVE
  To report the clinical features and outcome of a series of children with optic neuritis.
  
  
  METHODS
  We reviewed the medical records of patients up to 16 years old with optic neuritis. Group 1 comprised children seen up to two weeks after the onset of visual loss; Group 2 comprised patients already harboring optic atrophy.
  
  
  RESULTS
  There were 15 boys and 12 girls. The mean age was 10.9 years. Bilateral optic neuritis occurred in 10. Optic disc pallor was found in 35%, edema in 46%, and 19% had normal fundus. During follow-up visual acuity improved in all but one eye in Group 1, and in six of seven eyes in children in Group 2. Just one child converted to multiple sclerosis.
  
  
  CONCLUSIONS
  This study shows that the clinical features of childhood optic neuritis differ from those observed in adults. In children it has a better visual outcome and a lower conversion rate to multiple sclerosis than in adults.
authors.affiliation: Department of Neuro-Ophthalmology, Hospital São Geraldo, Federal University of Minas Gerais Medical School, Belo Horizonte, MG, Brazil. lanapma@zaz.com.br
authors.forename: M A
authors.initials: MA
authors.lastname: Lana-Peixoto
authors.forename: G C
authors.initials: GC
authors.lastname: Andrade
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000209:etiology; D009902:Optic Neuritis / Q000150:complications / Q000503:physiopathology*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology