Approach to high-resolution ex situ NMR spectroscopy.
Nuclear magnetic resonance (NMR) experiments are typically performed with samples immersed in a magnet shimmed to high homogeneity. However, there are many circumstances in which it is impractical or undesirable to insert objects or subjects into the bore of a high-field magnet. Here we present a methodology based on an adaptation of nutation echoes that provides resolved spectra in the presence of matched inhomogeneous static and radiofrequency fields, thereby opening the way to high-resolution ex situ NMR. The observation of chemical shifts is regained through the use of multiple-pulse sequences of correlated, composite z-rotation pulses, producing resolved NMR spectra of liquid samples.
Meriles
C A
CA
Materials Sciences Division, Lawrence Berkeley National Laboratory and Department of Chemistry, University of California, Berkeley, CA 94720, USA.
Sakellariou
D
D
Heise
H
H
Moule
A J
AJ
Pines
A
A
D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008280:Magnetics; D011522:Protons; D012399:Rotation; D012996:Solutions
D011522:Protons; D012996:Solutions