Pelvic venoablation with ethanol for the treatment of erectile dysfunction due to veno-occlusive dysfunction.
OBJECTIVE
To perform pelvic venoablation with ethanol injection into the deep dorsal vein for the treatment of 10 patients with venogenic erectile dysfunction. This procedure was easily performed without any selective embolization technique. The efficacy and safety of this technique are discussed.


METHODS
A total of 10 patients with veno-occlusive dysfunction, severe enough to make vaginal insertion impossible, underwent pelvic venoablation with ethanol. The mean patient age was 67.1 years. Under spinal anesthesia, after the venous leaks were identified by cavernosography, a 20-gauge flexible needle was inserted into the deep dorsal vein. The pelvic venogram obtained with deep dorsal venography was included in what was revealed by the venogram obtained with cavernosography. A mixture of absolute ethanol and contrast medium (4:1) was used as a sclerosing agent. Under fluoroscopic control, the sclerosing agents were injected into the deep dorsal vein through a flexible needle. Success was defined as the ability to achieve vaginal insertion without the aid of any drugs, vasoactive injections, penile prosthesis, or vacuum device.


RESULTS
The follow-up ranged from 25 to 37 months (mean 32.3). At the short-term follow-up visit (less than 6 months), 7 patients (70%) reported erections sufficient for vaginal insertion; at the long-term follow-up visit, 5 men (50%) reported sustained, sufficient potency and 5 (50%) reported persistent erectile dysfunction. No serious complications occurred.


CONCLUSIONS
Our pelvic venoablation technique using ethanol was effective, minimally invasive, and cost-effective.
Miwa
Y
Y
Department of Urology, Fukui Medical University, Fukui, Japan.
Shioyama
R
R
Itou
Y
Y
Kanamaru
H
H
Okada
K
K
D000368:Aged; D007172:Erectile Dysfunction / Q000209:etiology / Q000628:therapy*; D000431:Ethanol / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010413:Penis / Q000098:blood supply*; D010690:Phlebography; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*
D012597:Sclerosing Solutions; D000431:Ethanol