title: Structural characterization of a pentadienyl radical intermediate formed during catalysis by prostaglandin H synthase-2.
authors.forename: S
authors.initials: S
authors.lastname: Peng
authors.forename: N M
authors.initials: NM
authors.lastname: Okeley
authors.forename: A L
authors.initials: AL
authors.lastname: Tsai
authors.forename: G
authors.initials: G
authors.lastname: Wu
authors.forename: R J
authors.initials: RJ
authors.lastname: Kulmacz
authors.forename: W A
authors.initials: WA
authors.lastname: van der Donk
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002384:Catalysis; D051546:Cyclooxygenase 2; D004578:Electron Spin Resonance Spectroscopy; D007527:Isoenzymes / Q000737:chemistry / Q000378:metabolism*; D008968:Molecular Conformation; D044262:Prostaglandin H2; D011451:Prostaglandin-Endoperoxide Synthases / Q000737:chemistry / Q000378:metabolism*; D011462:Prostaglandins G / Q000138:chemical synthesis / Q000737:chemistry*; D011463:Prostaglandins H / Q000096:biosynthesis / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007527:Isoenzymes; D011462:Prostaglandins G; D011463:Prostaglandins H; D044262:Prostaglandin H2; C038291:prostaglandin G2; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases