Study of fungicidal and antibacterial effect of the Cu(II)-complexes of thiophene oligomers synthesized in ZSM-5 zeolite channels.
The influence of the Cu(II)-complexes of thiophene oligomers synthesized by oxidative polymerization of thiophene with Cu2+ ions in ZSM-5 zeolite channels on fungicidal and antimicrobial properties was studied. It has been found that the heterogeneous system culture medium-modified zeolite increases sporulation of the tested fungus (Aspergillus niger) and concurrently kills yeast (Candida albicans). These effects are attributed to a slow release of Cu2+ ions and thiophene oligomers into the culture medium. As for the tested bacteria (G+ Staphylococcus aureus, G- Escherichia coli), the percentage of the killed cells increases due to light activation of the system. The light effect is assigned to photogeneration of the reactive oxygen species (ROS), mainly *OH radicals, which were registered in the water solution by EPR spectroscopy. It has been confirmed that the thiophene oligomers present in the Cu-ZSM-5 microstructure slow down the release of copper into the medium.
Cík
G
G
Department of Environmental Science, Slovak University of Technology, Bratislava, Slovak Republic. cik@chtf.stuba.sk
Bujdáková
H
H
Sersen
F
F
D002176:Candida albicans / Q000187:drug effects; D003300:Copper / Q000737:chemistry* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D007477:Ions; D008027:Light; D008826:Microbial Sensitivity Tests; D010084:Oxidation-Reduction; D011108:Polymers; D017382:Reactive Oxygen Species; D013211:Staphylococcus aureus / Q000187:drug effects; D013876:Thiophenes / Q000138:chemical synthesis / Q000494:pharmacology*; D017641:Zeolites
D007477:Ions; D011108:Polymers; D017382:Reactive Oxygen Species; D013876:Thiophenes; D017641:Zeolites; D003300:Copper