title: Anaesthetic considerations for a child with combined Prader-Willi syndrome and mitochondrial myopathy.
abstract: We report the anaesthetic management of a child with Prader-Willi syndrome and mitochondrial myopathy for open heart surgery. We used ketamine, fentanyl, rocuronium and caudal morphine together with a propofol infusion with no untoward effects. The implications of both conditions for anaesthesia are discussed.
authors.affiliation: Department of Anaesthesiology, Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: A D
authors.initials: AD
authors.lastname: Sharma
authors.forename: T
authors.initials: T
authors.lastname: Erb
authors.forename: S R
authors.initials: SR
authors.lastname: Schulman
authors.forename: G
authors.initials: G
authors.lastname: Sreeram
authors.forename: T F
authors.initials: TF
authors.lastname: Slaughter
mesh_terms: D000700:Analgesics; D000732:Androstanols; D000758:Anesthesia / Q000379:methods*; D000778:Anesthetics, Dissociative; D018686:Anesthetics, Intravenous; D002405:Catheterization, Central Venous; D002675:Child, Preschool; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000601:surgery*; D006801:Humans; D007649:Ketamine; D017240:Mitochondrial Myopathies / Q000150:complications*; D016343:Monitoring, Intraoperative; D009020:Morphine; D003473:Neuromuscular Nondepolarizing Agents; D011218:Prader-Willi Syndrome / Q000150:complications*; D015742:Propofol; D000077123:Rocuronium
chemical_list: D000700:Analgesics; D000732:Androstanols; D000778:Anesthetics, Dissociative; D018686:Anesthetics, Intravenous; D003473:Neuromuscular Nondepolarizing Agents; D007649:Ketamine; D009020:Morphine; D000077123:Rocuronium; D015742:Propofol