title: Low physical performance in obese adolescent boys with metabolic syndrome.
abstract: OBJECTIVE
  To assess cardiorespiratory exercise function in obese children with and without metabolic syndrome (MS).
  
  
  METHODS
  Comparing three groups of subjects with different cardiovascular risk profiles.
  
  
  METHODS
  Twenty-two MS (body weight (mean+/-s.d.) 97.3+/-15.3 kg; age (mean+/-s.d.) 14.2+/-1.9 y), 17 obese (82.6+/-15.7 kg; 14.2+/-2.6 y) and 29 normal weight control (64.3+/-8.5 kg; 15.3+/-1.0 y) boys.
  
  
  METHODS
  Exercise duration (ED), resting heart rate (HR(0)), peak heart rate (HR(peak)), physical working capacity at 170 beat/min (PWC-170), peak oxygen consumption (VO(2peak)) and the lactic acidosis threshold (LAT) were determined on treadmill, using a continuous ramp protocol.
  
  
  RESULTS
  ED (MS (mean+/-s.d.); 655+/-86 s; obese 703+/-64 s; control 750+/-0 s) in absolute value and PWC-170 normalised for body weight (139+/-40 w; 177+/-40 w; 211+/-40 w) were significantly shorter and lower in the MS group, as compared to obese and control groups (P<0.05). VO(2peak) (2.2+/-0.4 l/min; 2.4+/-0.5 l/min; 2.9+/-0.4 l/min) and LAT (1.3+/-0.4 l/min; 1.5+/-0.4 l/ min; 1.8+/-0.4 l/min) normalised for body weight, were significantly shorter and lower in the MS group, as compared to control group (P<0.05). HR(0) was significantly higher (P<0.05) in MS group than in obese and control groups (88+/-12 bpm; obese 78+/-10 bpm; 73+/-10 bpm).
  
  
  CONCLUSIONS
  Cardiorespiratory exercise performance capacity in MS boys are reduced. It still remains to be elucidated whether the metabolic alterations or the decreased physical activity is responsible for the observed reduction in cardiorespiratory performance.
authors.affiliation: Department of Paediatrics, University of Pécs, Pécs, Hungary. torokat@apacs.pote.hu
authors.forename: K
authors.initials: K
authors.lastname: Török
authors.forename: Z
authors.initials: Z
authors.lastname: Szelényi
authors.forename: J
authors.initials: J
authors.lastname: Pórszász
authors.forename: D
authors.initials: D
authors.lastname: Molnár
mesh_terms: D000140:Acidosis, Lactic; D000293:Adolescent; D002318:Cardiovascular Diseases; D016022:Case-Control Studies; D015331:Cohort Studies; D015444:Exercise / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000503:physiopathology*; D010101:Oxygen Consumption / Q000502:physiology*; D012307:Risk Factors
chemical_list: D008055:Lipids