The effect of cholecystokinin in controlling appetite and food intake in humans.
The present review of the satiating effect of cholecystokinin in humans has revealed that cholecystokinin is a physiological satiety factor in humans. The results demonstrate the efficacy of the satiating actions of exogenous and endogenous CCK in humans. The therapeutic potential of CCK analogues cannot be estimated until further studies are performed that demonstrate the efficacy of CCK analogues for decreasing body weight, and the safety of CCK when administered repetitively for prolonged periods.
Degen
L
L
Division of Gastroenterology, University Hospital of Basel, CH-4031 Basel, Switzerland.
Matzinger
D
D
Drewe
J
J
Beglinger
C
C
D000818:Animals; D001066:Appetite; D001835:Body Weight; D002766:Cholecystokinin / Q000502:physiology*; D005247:Feeding Behavior; D001068:Feeding and Eating Disorders; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans
D002766:Cholecystokinin