title: Interferon-alpha 2a treatment of neuro-Behcet disease.
abstract: Behcet disease is a multisystemic, chronic, recurrent inflammatory disorder characterized as a triad of hypopyon uveitis, oral aphthae, and genital ulcers. Neurologic involvement in Behcet disease (neuro-Behcet) is common. Neuro-Behcet disease typically manifests late after disease onset, rarely coincides with ocular involvement, and often heralds a poor prognosis for final vision and survival. We present a case of neuro-Behcet disease with neurologic onset concomitant with systemic and ocular involvement that was responsive to treatment with interferon-alpha 2a.
authors.affiliation: Saint Louis University Eye Institute, Missouri 63104, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Nichols
authors.forename: A
authors.initials: A
authors.lastname: Ince
authors.forename: L
authors.initials: L
authors.lastname: Akduman
authors.forename: E S
authors.initials: ES
authors.lastname: Mann
mesh_terms: D001528:Behcet Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008297:Male; D010211:Papilledema / Q000175:diagnosis / Q000188:drug therapy; D011994:Recombinant Proteins
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins