title: Advanced gallbladder carcinoma with biliobiliary fistula, resected by hepatopancreatoduodenectomy, in an aged patient.
abstract: We report a 78-year-old man with a gallbladder carcinoma and biliobiliary fistula, diagnosed by percutaneous transhepatic cholangioscopic biopsy through the fistula. The impacted stones in the common hepatic duct were crushed, and then selective cholangiography under percutaneous transhepatic cholangioscopy (PTCS) revealed a biliobiliary fistula. Cholangioscopic biopsy tissues taken from the gallbladder revealed adenocarcinoma, but biopsies taken from the fistula revealed no evidence of malignancy. Further investigations indicated that the gallbladder carcinoma involved the duodenum and the distal common bile duct. A hepatopancreatoduodenectomy, including both an extended right hepatic lobectomy with resection of the caudate lobe and a pancreatoduodenectomy, was performed. Despite the patient's advanced age, he made an unremarkable postoperative recovery and was able to enjoy an active social life for 8 months after the surgery. We discuss biliobiliary fistula associated with gallbladder carcinomas and the use of hepatopancreatoduodenectomy for advanced biliary cancer in aged patients.
authors.affiliation: Department of Surgery, Tohkai Hospital, Nagoya, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Iwahashi
authors.forename: N
authors.initials: N
authors.lastname: Hayakawa
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
authors.forename: A
authors.initials: A
authors.lastname: Maki
authors.forename: Y
authors.initials: Y
authors.lastname: Kawabata
authors.forename: A
authors.initials: A
authors.lastname: Murayama
authors.forename: J
authors.initials: J
authors.lastname: Kamiya
authors.forename: M
authors.initials: M
authors.lastname: Nagino
authors.forename: Y
authors.initials: Y
authors.lastname: Nimura
mesh_terms: D000368:Aged; D001658:Biliary Fistula / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D001660:Biliary Tract Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D002277:Carcinoma / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D016145:Endoscopy, Digestive System; D017809:Fatal Outcome; D005500:Follow-Up Studies; D005706:Gallbladder Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008297:Male; D016577:Pancreaticoduodenectomy / Q000379:methods*; D011859:Radiography; D012720:Severity of Illness Index; D016896:Treatment Outcome