[Interaction of lactoferrin with plasmid DNA studied by laser correlation spectroscopy].
The interactions of lactoferrin with plasmid DNAs substantially differing in the number of affine regions were studied. The dissociation constants for protein-nucleic acid complexes were determined. The possibility of standardizing the conditions for preparing multicomponent systems for gene-substituting therapy by laser correlation spectroscopy is discussed.
Danilova
I G
IG
St. Petersburg Institute of Nuclear Physics, Russian Academy of Sciences, Gatchina, 188300 Russia.
Sinogeeva
N I
NI
Shavlovskiĭ
M M
MM
Gaĭtskhoki
V S
VS
Noskin
L A
LA
D005260:Female; D006801:Humans; D007781:Lactoferrin / Q000737:chemistry*; D007834:Lasers; D008895:Milk, Human / Q000737:chemistry; D010957:Plasmids / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods
D007781:Lactoferrin