title: A prospective study of sex-specific effects of major depression on alcohol consumption.
abstract: OBJECTIVE
  To evaluate the impact of major depression on alcohol use in the Canadian general population.
  
  
  METHODS
  This study was based on a 2-year follow-up of the Canadian National Population Health Survey (NPHS) longitudinal cohort. Subjects reporting various patterns of drinking, with and without major depression, were selected using the 1994-95 NPHS data. Data collected during a reevaluation of these subjects 2 years later were analyzed to determine whether having major depression at the 1994-95 interview predicted subsequent changes in drinking patterns.
  
  
  RESULTS
  Subjects who were depressed in 1994-95 were generally not at higher risk of starting drinking or drinking more frequently than once a week. However, women who were depressed, especially those who were 19 years old or older, were at higher risk of having 5 or more drinks at least once monthly.
  
  
  CONCLUSIONS
  These results confirm that mood disorders can impact on alcohol consumption in women. A component of the well-known association between alcohol consumption and major depression is due to "reverse" causal effects. Proper management of depression in women may contribute to the prevention of problem drinking.
authors.affiliation: Department of Community Health and Epidemiology, Faculty of Medicine, Dalhousie University, 5849 University Avenue, Halifax, NS B3H 4H7. Jwang@tupdean2.med.dal.ca
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: S B
authors.initials: SB
authors.lastname: Patten
mesh_terms: D000428:Alcohol Drinking / Q000523:psychology*; D000437:Alcoholism / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology*; D003865:Major Depressive Disorder / Q000453:epidemiology / Q000523:psychology*; D005500:Follow-Up Studies; D006801:Humans; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012737:Sex Factors