title: Understanding the interaction between environmental exposures and molecular events in colorectal carcinogenesis.
authors.affiliation: Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., EPS 7236, Rockville, MD 20892, USA. Ishiben@exchange.nih.gov
authors.forename: N
authors.initials: N
authors.lastname: Ishibe
authors.forename: A N
authors.initials: AN
authors.lastname: Freedman
mesh_terms: D000236:Adenoma / Q000139:chemically induced / Q000235:genetics; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects; D002277:Carcinoma / Q000139:chemically induced / Q000235:genetics; D018797:Cell Cycle Proteins; D002471:Cell Transformation, Neoplastic / Q000139:chemically induced / Q000235:genetics; D015179:Colorectal Neoplasms / Q000139:chemically induced* / Q000235:genetics*; D050760:Cyclin-Dependent Kinase Inhibitor p27; D004043:Dietary Fiber / Q000008:administration & dosage; D004781:Environmental Exposure / Q000009:adverse effects*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005492:Folic Acid / Q000378:metabolism; D017491:Genes, APC / Q000187:drug effects; D016163:Genes, DCC / Q000235:genetics; D016147:Genes, Tumor Suppressor / Q000187:drug effects*; D019254:Genes, bcl-2 / Q000187:drug effects; D016158:Genes, p53 / Q000235:genetics; D011905:Genes, ras / Q000235:genetics; D006801:Humans; D008745:Methylation; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D008869:Microtubule-Associated Proteins / Q000235:genetics; D009154:Mutation / Q000187:drug effects; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000235:genetics; D012907:Smoking / Q000009:adverse effects; D025521:Tumor Suppressor Proteins
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018797:Cell Cycle Proteins; D004043:Dietary Fiber; D004791:Enzyme Inhibitors; D008869:Microtubule-Associated Proteins; D025521:Tumor Suppressor Proteins; D050760:Cyclin-Dependent Kinase Inhibitor p27; D005492:Folic Acid; D000587:Oxidoreductases Acting on CH-NH Group Donors; D042965:Methylenetetrahydrofolate Reductase (NADPH2)