title: Epidural washout with high volumes of saline to accelerate recovery from epidural anaesthesia.
abstract: BACKGROUND
  Prolonged postoperative blockade can follow neuraxial blocks for short surgical procedures. We investigated whether washout with a high volume of saline through an epidural catheter could provide a faster recovery after epidural anaesthesia.
  
  
  METHODS
  Thirty patients were randomly assigned to a control group (no washout), to group 2x (epidural washout with twice the volume of 2% mepivacaine) and group 4x (epidural washout with four times that volume).
  
  
  RESULTS
  Recovery times from sensory blockade at L2 were 151+/-24, 122+/-29 and 116+/-24 min for control, 2x and 4x groups respectively. Significant differences were found in both saline groups when compared with control group, but not between group 2x and group 4x. No differences were found concerning motor blockade. One patient in group 4x demonstrated signs of intracranial hypertension. Mepivacaine plasma concentrations were increased by saline washout in group 4x.
  
  
  CONCLUSIONS
  Epidural washout with a high volume of saline can not be recommended since no clinically significant reduction in the recovery time can be achieved without risk.
authors.affiliation: Dept. of Anaesthesiology, Complexo Hospitalario Universitario de Santiago, Spain. jaimerodriguezgarcia@nacom.es
authors.forename: J
authors.initials: J
authors.lastname: Rodríguez
authors.forename: V
authors.initials: V
authors.lastname: Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: Naveira
authors.forename: O
authors.initials: O
authors.lastname: Quintela
authors.forename: M
authors.initials: M
authors.lastname: Bárcena
authors.forename: E
authors.initials: E
authors.lastname: Gallardo
authors.forename: F
authors.initials: F
authors.lastname: Gude
authors.forename: J
authors.initials: J
authors.lastname: Alvarez
mesh_terms: D000762:Anesthesia Recovery Period; D000767:Anesthesia, Epidural; D000779:Anesthetics, Local / Q000097:blood; D001794:Blood Pressure / Q000187:drug effects; D004311:Double-Blind Method; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008619:Mepivacaine / Q000097:blood; D008875:Middle Aged; D009407:Nerve Block; D012965:Sodium Chloride
chemical_list: D000779:Anesthetics, Local; D012965:Sodium Chloride; D008619:Mepivacaine