Virulence properties of oral bacteria: impact of molecular biology.
Dental caries and periodontitis, although generally not life threatening, are nevertheless of significant importance. An understanding of the molecular nature of these diseases could aid the development of novel methods of prevention and control, and increase our knowledge of their etiology. The identification of virulence factors in oral bacteria could lead to the development of vaccines directed against these organisms, the design of inhibitors of biofilm formation, and the development of replacement therapy strategies.
Kuramitsu
H K
HK
Department of Oral Biology, State University of New York, Buffalo 14214, USA. kuramits@acsu.buffalo.edu
D000188:Actinobacillus / Q000472:pathogenicity; D000818:Animals; D001419:Bacteria / Q000235:genetics / Q000472:pathogenicity*; D001438:Bacteroidaceae / Q000472:pathogenicity; D018441:Biofilms; D003731:Dental Caries / Q000382:microbiology* / Q000503:physiopathology; D006801:Humans; D009055:Mouth / Q000382:microbiology*; D010518:Periodontitis / Q000382:microbiology* / Q000503:physiopathology; D013295:Streptococcus mutans / Q000472:pathogenicity; D014208:Treponema / Q000472:pathogenicity; D014774:Virulence