title: Epidemiologic estimate of the proportion of fatalities related to occupational factors in Finland.
abstract: OBJECTIVE
  This study attempts to estimate the proportion of annual deaths related to occupational factors in Finland and considers related methodological issues and associated uncertainties.
  
  
  METHODS
  Statistics on causes of death, numbers of subjects exposed, and risk ratios obtained from the epidemiologic literature were used to estimate the population attributable fraction and disease burden for causes of death from work-related diseases. Gender-, age- and disease-specific numbers of deaths were provided by Statistics Finland for 1996. Information on the size of the population, broken down by gender, age, occupation, and industry, was acquired from population censuses. A Finnish job-exposure matrix supplied data on the prevalence of exposure for specific agents and the level of exposure among exposed workers.
  
  
  RESULTS
  The attributable fraction of work-related mortality in the relevant disease and age categories was estimated to be 7% (10% for men and 2% for women), and for all diseases and ages the fraction was 4%. For the main cause-of-death categories, the attributable fraction became 12% for circulatory system diseases, 8% for malignant neoplasms, 4% for respiratory system diseases, 4% for mental disorders, 3% for nervous system diseases, and 3% for accidents and violence. The following estimates were obtained for specific important diseases: 24% for lung cancer, 17% for ischemic heart disease, 12% for chronic obstructive pulmonary disease, and 11% for stroke. Based on these fractions, the total number of work-related deaths that occurred in Finland in 1996 was calculated to be on the order of 1800 (employed work force of 2.1 million); 86% involved men.
  
  
  CONCLUSIONS
  High-quality epidemiologic studies and national survey data are essential for obtaining reliable estimates of the proportion of deaths attributable to occupational factors. The magnitude of work-related mortality is an insufficiently recognized contributor to total mortality in Finland, especially from circulatory diseases and other diseases caused by exposure to agents other than asbestos.
authors.affiliation: Department of Epidemiology and Biostatistics, Finnish Institute of Occupational Health, Helsinki. Markku.Nurminen@occuphealth.fi
authors.forename: M
authors.initials: M
authors.lastname: Nurminen
authors.forename: A
authors.initials: A
authors.lastname: Karjalainen
mesh_terms: D000328:Adult; D001249:Asthma / Q000401:mortality; D002318:Cardiovascular Diseases / Q000401:mortality; D002423:Cause of Death; D003327:Coronary Disease / Q000401:mortality; D005260:Female; D005387:Finland / Q000453:epidemiology; D005767:Gastrointestinal Diseases / Q000401:mortality; D006801:Humans; D008171:Lung Diseases / Q000401:mortality; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009422:Nervous System Diseases / Q000401:mortality; D009784:Occupational Diseases / Q000401:mortality*; D016273:Occupational Exposure / Q000706:statistics & numerical data; D010190:Pancreatic Neoplasms / Q000401:mortality; D029424:Pulmonary Disease, Chronic Obstructive / Q000401:mortality; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology