Circumstances at HIV diagnosis and progression of disease in older HIV-infected Americans.
OBJECTIVE
This study identified age-related differences in diagnosis and progression of HIV by analyzing a nationally representative sample of HIV-infected adults under care in the United States.


METHODS
We compared older (> or = 50 years) and younger participants stratified by race/ethnicity. Regression models controlled for demographic, therapeutic, and clinical factors.


RESULTS
Older non-Whites more often had HIV diagnosed when they were ill. Older and younger patients were clinically similar. At baseline, however, older non-Whites had fewer symptoms and were less likely to have AIDS, whereas at follow-up they had a trend toward lower survival.


CONCLUSIONS
Later HIV diagnosis in non-Whites merits public health attention; clinical progression in this group requires further study.
Zingmond
D S
DS
Division of General Internal Medicine and Health Services Research, UCLA Department of Medicine, 911 Broxton Plaza, Los Angeles, CA 90095-1736, USA. dzingmond@mednet.ucla.edu
Wenger
N S
NS
Crystal
S
S
Joyce
G F
GF
Liu
H
H
Sambamoorthi
U
U
Lillard
L A
LA
Leibowitz
A A
AA
Shapiro
M F
MF
Bozzette
S A
SA
D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged / Q000706:statistics & numerical data*; D018791:CD4 Lymphocyte Count; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy; D006304:Health Status; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012044:Regression Analysis; D011795:Surveys and Questionnaires; D016019:Survival Analysis; D014481:United States / Q000453:epidemiology