title: [Cerebral arterial aneurysm in a child with acquired immunodeficiency syndrome: case report].
abstract: Cerebral aneurysmal arteriopathy of the circle of Willis is an uncommon manifestation of acquired human immunodeficiency virus (HIV) infection and up to now only 15 cases have been published in the literature. For this reason we add our experience of this rare case, and review the most important aspects related to this entity. The patient is a 6 year old male with perinatal transmitted AIDS, tetraparethic, developed symptoms characterized by episodes of dystonic postures. The computed tomography of the brain showed aneurismal arteriopathy of the circle of Willis. He had a previous normal examination. The review of the literature shows the pathological abnormalities of the affected vessels are mainly medial fibrosis, with destruction of the internal elastic lamina and intimal hyperplasia. The etiology for the vasculitis is unknown. Varicela zoster virus, as well as HIV by itself, can be related to the physiopathology of the vasculitis. On conclusion, it can be said that although uncommon, such complications are of great importance by the fact that the patients with vascular aneurismal arteriopathy are in high risk for vascular accidents, and once a diagnosis was made, death occurs in less than 6 months, according to the literature.
authors.affiliation: Disciplina de Radiologia, Departamento de Clínica, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brasil.
authors.lastname: Carvalho Neto Ad
authors.forename: I
authors.initials: I
authors.lastname: Bruck
authors.forename: L O
authors.initials: LO
authors.lastname: Coelho
authors.forename: C R
authors.initials: CR
authors.lastname: Cruz
authors.forename: C B
authors.initials: CB
authors.lastname: Liu
authors.forename: A F
authors.initials: AF
authors.lastname: Gomes
authors.forename: S A
authors.initials: SA
authors.lastname: Ogata
authors.forename: T T
authors.initials: TT
authors.lastname: Tahan
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D002648:Child; D002941:Circle of Willis / Q000000981:diagnostic imaging; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D014057:Tomography, X-Ray Computed