title: Natural history and clinical outcome measures for multiple sclerosis studies. Why at the present time does EDSS scale remain a preferred outcome measure to evaluate disease evolution?
authors.forename: J F
authors.initials: JF
authors.lastname: Kurtzke
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods; D004185:Disability Evaluation; D018450:Disease Progression; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000503:physiopathology; D016896:Treatment Outcome