[Cellular composition of the spinal ganglion following neonatal administration of capsaicin in rats].
Single administration of 100 mg/kg of capsaicine to newborn rats causes 30% decline in neurocyte number, decrease of average area of section neurocytes and dystrophic changes of majority of cells developing in a month. In 3 and 6 months 60% decline of neurocyte number occur, increase of average neurocyte section area is retained, dystrophic changes in cells are less manifested. It was revealed through histogrammes that decline in neurocyte number was conditioned by reduction of fraction of small neurocytes. The results indicate the stable effect of chemical differentiation.
Rumiantseva
T A
TA
Department of Human Anatomy, State Medical Academy of Yaroslavle.
D000818:Animals; D002211:Capsaicin / Q000494:pharmacology*; D005727:Ganglia, Spinal / Q000187:drug effects* / Q000473:pathology; D008297:Male; D009336:Necrosis; D009474:Neurons / Q000473:pathology*; D051381:Rats
D002211:Capsaicin