title: Salvage resection after previous laryngeal surgery: total laryngectomy with en bloc resection of the overlying cervical skin.
abstract: OBJECTIVE
  To evaluate the effectiveness of extended total laryngectomy for the treatment of recurrences of laryngeal cancer.
  
  
  METHODS
  We conducted a retrospective clinical study of patients who had undergone extended total laryngectomy and were seen over a 15-year period. The follow-up period ranged from 3 to 15 years.
  
  
  METHODS
  Academic tertiary referral medical center.
  
  
  METHODS
  We observed 15 patients who were affected by a recurrence of laryngeal cancer that extended to the overlying soft tissue. All patients were male. The mean age was 61.5 years. Thirteen patients had previously undergone partial laryngeal surgery, and 2 patients had undergone radiation therapy, without success.
  
  
  METHODS
  All patients underwent total laryngectomy extending to the soft tissue, including the overlying skin.
  
  
  RESULTS
  Five of the 15 patients died of local recurrence, and 1 patient died of massive postoperative hemorrhaging. An actuarial survival rate of 60% was observed at 5 years.
  
  
  CONCLUSIONS
  Total laryngectomy extending to the soft tissues seems to be an effective procedure for treating local recurrences of laryngeal cancer after partial laryngectomy or failure of radiation therapy.
authors.affiliation: Department of Otolaryngology, La Sapienza University, Rome, Italy. andrea.gallo@uniroma1.it
authors.forename: A
authors.initials: A
authors.lastname: Gallo
authors.forename: R
authors.initials: R
authors.lastname: Moi
authors.forename: M
authors.initials: M
authors.lastname: Simonelli
authors.forename: D
authors.initials: D
authors.lastname: Vitolo
authors.forename: M L
authors.initials: ML
authors.lastname: Fiorella
authors.forename: V
authors.initials: V
authors.lastname: Marvaso
authors.forename: V
authors.initials: V
authors.lastname: Manciocco
authors.forename: M
authors.initials: M
authors.lastname: de Vincentiis
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D012086:Reoperation; D016879:Salvage Therapy; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D015996:Survival Rate