title: Parahydrogen-induced polarization in imaging: subsecond (13)C angiography.
abstract: High nuclear spin polarization of (13)C was reached in organic molecules. Enhancements of up to 10(4), compared to thermal polarization at 1.5 T, were achieved using the parahydrogen-induced polarization technique in combination with a field cycling method. While parahydrogen has no net polarization, it has a high spin order, which is retained when hydrogen is incorporated into another molecule by a chemical reaction. By subjecting this molecule to a sudden change of the external magnetic field, the spin order is transferred into net polarization. A (13)C angiogram of an animal was generated in less than a second. Magn Reson Med 46:1-5, 2001.
authors.affiliation: Nycomed Innovation AB, MEDEON, SE-205 12 Malmö, Sweden. Klaes.Golman@nycomedinnovation.se
authors.forename: K
authors.initials: K
authors.lastname: Golman
authors.forename: O
authors.initials: O
authors.lastname: Axelsson
authors.forename: H
authors.initials: H
authors.lastname: Jóhannesson
authors.forename: S
authors.initials: S
authors.lastname: Månsson
authors.forename: C
authors.initials: C
authors.lastname: Olofsson
authors.forename: J S
authors.initials: JS
authors.lastname: Petersson
mesh_terms: D000818:Animals; D002247:Carbon Isotopes; D006859:Hydrogen; D018810:Magnetic Resonance Angiography / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D051381:Rats; D013997:Time Factors
chemical_list: D002247:Carbon Isotopes; D006859:Hydrogen