title: Influence of coconut water on hemostasis.
abstract: Coconut water (CNW) can be used as short-term intravenous hydration and resuscitation fluid. We investigated the influence of coconut water on plasma coagulation in vitro. Either CNW or physiological saline (PS) was added to citrated plasma of 8 healthy volunteers. Coagulation capability of diluted plasma was evaluated by thrombelastography (TEG). Replacement of up to 50 % of citrated plasma by CNW or PS did not influence initiation of coagulation as indicated by split point and reaction time, respectively. Strength of fibrin clot as expressed by maximum amplitude (MA) of TEG recording dose dependently declined in both groups. Replacing 50 % of citrated plasma by CNW or PS reduced MA by 39% and 32%, respectively. The influence of coconut water on hemostasis as assessed by TEG does not differ from the effect caused by an identical volume of PS.
authors.affiliation: Department of Pharmacology & Toxicology, University of Heidelberg at Mannheim, Mannheim, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Pummer
authors.forename: P
authors.initials: P
authors.lastname: Heil
authors.forename: W
authors.initials: W
authors.lastname: Maleck
authors.forename: G
authors.initials: G
authors.lastname: Petroianu
mesh_terms: D001777:Blood Coagulation / Q000502:physiology*; D003059:Cocos; D004630:Emergencies; D005260:Female; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D007262:Infusions, Intravenous; D008297:Male; D015532:Rehydration Solutions; D012151:Resuscitation / Q000379:methods*
chemical_list: D015532:Rehydration Solutions