title: Correlation between medium acidification and pathogenicity in environmental halophilic non-cholera vibrios.
abstract: OBJECTIVE
  The metabolic characterization and pathogenicity of vibrios isolated from seafood were studied.
  
  
  RESULTS
  Strains of halophilic vibrios, grown in the presence of 0.5% glucose, induced high medium acidification and were non-culturable after 24 h, while moderately acidifying strains were culturable, produced cytotoxins, and remained lethal when inoculated intraperitoneally in mice. Highly acidifying strains failed to elicit pathogenicity in vivo and in vitro.
  
  
  CONCLUSIONS
  The high acidification of the medium and the self-killing activity of NCVs might be considered a significant phenotypic marker of virulence and/or cytotoxicity.
  
  
  CONCLUSIONS
  We suggest the medium acidification test as possible screening method for pathogenic NCVs in food microbiology.
authors.affiliation: Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, Ancona, Italy. dottaviani@katamail.com
authors.forename: D
authors.initials: D
authors.lastname: Ottaviani
authors.forename: I
authors.initials: I
authors.lastname: Bacchiocchi
authors.forename: L
authors.initials: L
authors.lastname: Masini
authors.forename: A
authors.initials: A
authors.lastname: Carraturo
authors.forename: G L
authors.initials: GL
authors.lastname: Russo
authors.forename: M
authors.initials: M
authors.lastname: Giammarioli
authors.forename: G
authors.initials: G
authors.lastname: Sbaraglia
mesh_terms: D000818:Animals; D003470:Culture Media; D005285:Fermentation; D005947:Glucose / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D051379:Mice; D017747:Seafood / Q000382:microbiology; D014733:Vibrio / Q000254:growth & development / Q000378:metabolism* / Q000472:pathogenicity*; D014735:Vibrio Infections / Q000382:microbiology; D014774:Virulence
chemical_list: D003470:Culture Media; D005947:Glucose