Photosensitivity induced by oral itraconazole.
A case of photosensitivity induced by itraconazole is reported. A 70-year-old woman had erythema, oedema and vesicles on sun-exposed areas after 5 days of itraconazole treatment for oral candidiasis. Oral photochallenge using itraconazole and sun irradiation was positive, but photopatch test was negative. Photosensitivity from azoles is an uncommon adverse effect. Only three other cases have been described, two induced by ketoconazole and one by itraconazole.
Alvarez-Fernández
J G
JG
Department of Dermatology, Hospital Universitario 12 de Octubre, Madrid. Spain.
Castaño-Suárez
E
E
Cornejo-Navarro
P
P
de la Fuente
E G
EG
Ortiz de Frutos
F J
FJ
Iglesias-Diez
L
L
D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002180:Candidiasis, Oral / Q000175:diagnosis / Q000188:drug therapy; D017454:Dermatitis, Photoallergic / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017964:Itraconazole / Q000009:adverse effects* / Q000627:therapeutic use; D018570:Risk Assessment
D000935:Antifungal Agents; D017964:Itraconazole