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D000328:Adult; D000368:Aged; D001284:Atrophy; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D014621:Vagina / Q000473:pathology