Cognitive function in amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder of unknown etiology. Although there was a widely held belief that ALS does not cause cognitive impairment, cognitive function in patients with ALS has received more attention recently. In this paper, we discuss the clinical, neuroanatomical and neuropathological basis for cognitive dysfunction in ALS.
Abe
K
K
Department of Neurology, Osaka University Graduate School of Medicine, Suita, Japan. abe@neurol.med.osaka-u.ac.jp
D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D003071:Cognition; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D009460:Neurologic Examination; D015899:Tomography, Emission-Computed, Single-Photon