title: Delivery of biological performance via micro-encapsulation formulation chemistry.
abstract: Lambda-cyhalothrin micro-capsules have been prepared by a novel in situ procedure. Manipulation of the chemistry has led to slow- and fast-release formulations. The latter has a biological performance comparable to commercial lambda-cyhalothrin emulsifiable concentrates, but exhibits a significantly improved toxicological profile over EC, WP and WG formulations. Micro-encapsulation technology satisfies many of the drivers towards the safer use of pesticides.
authors.affiliation: Zeneca Agrochemicals, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6ET, UK. ian.shirley@aguk.zeneca.com
authors.forename: I M
authors.initials: IM
authors.lastname: Shirley
authors.forename: H B
authors.initials: HB
authors.lastname: Scher
authors.forename: R M
authors.initials: RM
authors.lastname: Perrin
authors.forename: P J
authors.initials: PJ
authors.lastname: Wege
authors.forename: M
authors.initials: M
authors.lastname: Rodson
authors.forename: J L
authors.initials: JL
authors.lastname: Chen
authors.forename: A W
authors.initials: AW
authors.lastname: Rehmke
mesh_terms: D001682:Biological Availability; D002214:Capsules; D055598:Chemical Phenomena; D002622:Chemistry, Agricultural; D002627:Chemistry, Physical; D003692:Delayed-Action Preparations; D004339:Drug Compounding; D005079:Excipients; D007306:Insecticides / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics* / Q000633:toxicity; D009570:Nitriles; D011722:Pyrethrins / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics* / Q000633:toxicity; D014481:United States; D014484:United States Environmental Protection Agency / Q000592:standards*
chemical_list: D002214:Capsules; D003692:Delayed-Action Preparations; D005079:Excipients; D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C037304:cyhalothrin