title: Laparoscopic pancreatic surgery in patients with neuroendocrine tumours: indications and limits.
abstract: Laparoscopic pancreatic procedures are still at an evaluation stage with regard to their indications and techniques. Between January 1998 and December 2000, 13 patients with endocrine pancreatic tumours - 11 insulinomas and 2 non-functioning tumours-underwent laparoscopic surgery, laparoscopic ultrasonography being used in all the patients. Enucleation was performed in five patients. The operative time was 2-3 hours. Distal pancreatectomy was performed in six patients with insulinomas, and spleen preservation with intact splenic vessels was feasible in five. Splenectomy was necessary in one patient for technical reasons. Laparoscopic distal pancreatectomy with splenic vessel preservation was performed in two patients with a large (6 and 8 cm) non-functioning tumour. The mean operative time for all the patients undergoing distal pancreatectomy was 4 hours, ranging from 3 to 5 hours. A pancreatic fistula occurred in three patients after tumour enucleation and in two patients after distal pancreatectomy; the mean hospital stay for all patients was 5 days. Enucleation guided by laparoscopic ultrasonography thus allows safe tumour dissection and excision, laparoscopic distal pancreatectomy also being feasible and safe. Splenic salvage with splenic vessel preservation is technically possible. The laparoscopic approach allows a shorter hospital stay and an earlier return to normal activities.
authors.affiliation: Department of Surgery, Institute of Digestive Diseases IMD, Hospital Clinic, University of Barcelona, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Fernández-Cruz
authors.forename: M
authors.initials: M
authors.lastname: Herrera
authors.forename: A
authors.initials: A
authors.lastname: Sáenz
authors.forename: J P
authors.initials: JP
authors.lastname: Pantoja
authors.forename: E
authors.initials: E
authors.lastname: Astudillo
authors.forename: M
authors.initials: M
authors.lastname: Sierra
mesh_terms: D000328:Adult; D000368:Aged; D018278:Carcinoma, Neuroendocrine / Q000601:surgery*; D005260:Female; D006801:Humans; D007340:Insulinoma / Q000601:surgery*; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000601:surgery*