Iron-deficient erythropoiesis in premature infants measured by blood zinc protoporphyrin/heme.
We measured red blood cell zinc protoporphyrin/heme (ZnPP/H) ratios in premature infants at hospital discharge. ZnPP/heme ratios correlated directly with red blood cell distribution width and reticulocyte number. As in other populations, ZnPP/H ratios may provide a simple measure of iron-deficient erythropoiesis in premature infants.
Winzerling
J J
JJ
Department of Nutritional Sciences, Steele Memorial Children's Research Center, The University of Arizona, Tucson, USA.
Kling
P J
PJ
D001772:Blood Cell Count; D004791:Enzyme Inhibitors / Q000097:blood; D004920:Erythropoiesis; D005260:Female; D005293:Ferritins / Q000097:blood; D006418:Heme / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood*; D000090463:Iron Deficiencies; D008297:Male; D011524:Protoporphyrins / Q000097:blood
D004791:Enzyme Inhibitors; D011524:Protoporphyrins; C017803:zinc protoporphyrin; D006418:Heme; D005293:Ferritins