Alkaloids and flavonoids from peanut skins.
Separation of the water-soluble fraction of peanut skins led to the isolation of 8 flavonoids and two novel indole alkaloids. Two new flavonoid glycosides have been identified as isorhamnetin 3-O-[2-O-beta-glucopyranosyl-6-O-alpha-rhamnopyranosyl]- beta-glucopyranoside and 3',5,7-trihydroxyisoflavone-4'-methoxy-3'-O-beta-glucopyranoside. Two alkaloids are 2-methoxyl-3-(3-indolyl)-propionic acid and 2-hydroxyl-3-[3-(1-N-methyl)-indolyl]-propionic acid. These isolated flavonoids were evaluated for their free radical scavenging activity and protein glycation inhibitory effects.
Lou
H
H
School of Pharmaceutical Sciences, Shandong University, Jinan, P. R. China. hxlou@jn-public.sd.cninfo.net
Yuan
H
H
Yamazaki
Y
Y
Sasaki
T
T
Oka
S
S
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010367:Arachis / Q000737:chemistry*; D015764:Bepridil / Q000031:analogs & derivatives* / Q000737:chemistry; D001713:Biphenyl Compounds; D002851:Chromatography, High Pressure Liquid; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology; D017127:Glycation End Products, Advanced; D009682:Magnetic Resonance Spectroscopy; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D008517:Phytotherapy; D010851:Picrates; D010946:Plants, Medicinal / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D012431:Rutin / Q000737:chemistry / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
D000470:Alkaloids; D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D005960:Glucosides; D017127:Glycation End Products, Advanced; D010851:Picrates; D012710:Serum Albumin, Bovine; D012431:Rutin; D015764:Bepridil; D011794:Quercetin; C004931:1,1-diphenyl-2-picrylhydrazyl; C110309:quercetin 3-O-glucopyranoside