title: Islet transplantation: present clinical situation and future aspects.
abstract: Beta-cell replacement either by pancreatic organ or islet cell transplantation is the only treatment to achieve an insulin-independent, normoglycemic state and to avoid hypoglycemic episodes in patients with type 1 diabetes mellitus. This article will review the state-of-the-art in clinical islet cell transplantation at the dawn of the new millennium and will provide an outlook on the basis of extended personal experience.
authors.affiliation: Third Medical Department and Policlinic, Justus-Liebig-University, Giessen, Germany. reinhard.bretzel@innere.med.uni-giessen.de
authors.forename: R G
authors.initials: RG
authors.lastname: Bretzel
authors.forename: M
authors.initials: M
authors.lastname: Brendel
authors.forename: M
authors.initials: M
authors.lastname: Eckhard
authors.forename: D
authors.initials: D
authors.lastname: Brandhorst
authors.forename: C
authors.initials: C
authors.lastname: Jaeger
authors.forename: E
authors.initials: E
authors.lastname: Hatziagelaki
authors.forename: K
authors.initials: K
authors.lastname: Federlin
mesh_terms: D006084:Graft Rejection; D006801:Humans; D007391:International Cooperation; D016381:Islets of Langerhans Transplantation / Q000639:trends; D012042:Registries