title: Arthroscopic synovectomy for rheumatoid arthritis using a holmium:YAG laser.
abstract: OBJECTIVE
  To determine the usefulness of the holmium:YAG laser system in arthroscopic synovectomy (ASSX) for treating rheumatoid arthritis (RA).
  
  
  METHODS
  ASSX was performed on 15 knees (one Larsen Grade 1, 7 Grade 2, 7 Grade 3) and 8 ankles (6 Grade 2, 2 Grade 3) of 17 female patients with RA. The average age at ASSX was 50.6 years (25-70). The average followup period was 24.4 months (10-47).
  
  
  RESULTS
  Seven out of 8 knees with grade 1 or 2 had reduced pain and swelling, as well as decreased average serum levels of C-reactive protein (CRP) (from 3.6+/-1.1 to 1.4+/-0.3 mg/dl). However, 4 out of 7 knees with grade 3 showed recurrence of pain and swelling along with persistent average serum level of CRP (from 4.3+/-1.0 to 3.8+/-1.0 mg/dl). All 8 ankles with Grade 2 or Grade 3 experienced reduced pain and swelling, while the average serum CRP levels did not change (from 3.2+/-0.9 to 2.9+/-1.0 mg/dl).
  
  
  CONCLUSIONS
  The Holmium:YAG laser was useful in ASSX for treating RA knees and ankles.
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Takagi
authors.forename: T
authors.initials: T
authors.lastname: Koshino
authors.forename: R
authors.initials: R
authors.lastname: Okamoto
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006695:Holmium; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D053685:Laser Therapy / Q000295:instrumentation*; D008875:Middle Aged; D011859:Radiography; D000074402:Synovectomy
chemical_list: D006695:Holmium