title: [Immunological status of patients with epidemic parotitis].
abstract: Immunosuppression was detected in six patients with parotitis. The proliferation of peripheral blood mononuclear cells, NK activity, and CD4/CD8 index decreased, while the production of tumor necrosis factor alpha and interleukin 1 beta increased on day 1 after clinical manifestation of mumps. The clinical diagnosis of mumps was confirmed by serological analysis of paired sera. Besides parotitis virus, herpes simplex type 1 virus was detected in two saliva samples by the polymerase chain reaction. Herpes (lip vesicles) manifested in these patients on days 8 and 11 after manifestation of parotitis.
authors.forename: A P
authors.initials: AP
authors.lastname: Agafonov
authors.forename: M A
authors.initials: MA
authors.lastname: Strel'tsova
authors.forename: I M
authors.initials: IM
authors.lastname: Susloparov
authors.forename: G M
authors.initials: GM
authors.lastname: Ignat'ev
mesh_terms: D002648:Child; D006801:Humans; D007113:Immunity, Innate; D007165:Immunosuppression Therapy; D007375:Interleukin-1 / Q000276:immunology; D008297:Male; D009107:Mumps / Q000276:immunology*; D009109:Mumps virus / Q000276:immunology* / Q000302:isolation & purification; D016176:T-Lymphocyte Subsets / Q000276:immunology; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology
chemical_list: D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha