Implications of lipid microdomains for membrane curvature, budding and fission.
Recent studies have highlighted the importance of monolayer and bilayer curvature for the budding and fission of biological membranes. Other lines of research, addressing the structure of planar biological membranes, have revealed the existence of cholesterol-based membrane microdomains. Here, we comment on the significance of microdomains for curved membranes, with special emphasis on budding and fission.
Huttner
W B
WB
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307, Dresden, Germany.
Zimmerberg
J
J
D000818:Animals; D002462:Cell Membrane / Q000737:chemistry / Q000502:physiology; D022162:Cytoplasmic Vesicles / Q000378:metabolism; D008563:Membrane Lipids / Q000502:physiology; D021962:Membrane Microdomains / Q000502:physiology*; D008565:Membrane Proteins / Q000502:physiology
D008563:Membrane Lipids; D008565:Membrane Proteins