GDNF is trophic for mouse motoneurons that express a mutant superoxide dismutase (SOD1) gene.
Mitsumoto
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D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy*; D000818:Animals; D051100:Glial Cell Line-Derived Neurotrophic Factor; D051379:Mice; D008817:Mice, Mutant Strains; D009046:Motor Neurons / Q000187:drug effects* / Q000201:enzymology; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins / Q000494:pharmacology*; D018696:Neuroprotective Agents / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000235:genetics*; D000072105:Superoxide Dismutase-1
C495040:Gdnf protein, mouse; D051100:Glial Cell Line-Derived Neurotrophic Factor; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; D018696:Neuroprotective Agents; C000606291:Sod1 protein, mouse; D013482:Superoxide Dismutase; D000072105:Superoxide Dismutase-1