Affinities of cephalosporins for penicillin-binding proteins and their antibacterial activities in the presence of human serum albumin.
Fontana
R
R
Institute of Microbiology, University of Verona, Strada Le Grazie, 8, 37134 Verona, Italy.
Ligozzi
M
M
Cornaglia
G
G
D001426:Bacterial Proteins; D002352:Carrier Proteins / Q000378:metabolism*; D002439:Cefotaxime / Q000494:pharmacology; D002443:Ceftriaxone / Q000494:pharmacology; D002511:Cephalosporins / Q000378:metabolism / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D006602:Hexosyltransferases; D006801:Humans; D008826:Microbial Sensitivity Tests; D002267:Muramoylpentapeptide Carboxypeptidase / Q000378:metabolism*; D046915:Penicillin-Binding Proteins; D010458:Peptidyl Transferases; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism / Q000494:pharmacology*
D001426:Bacterial Proteins; D002352:Carrier Proteins; D002511:Cephalosporins; D046915:Penicillin-Binding Proteins; D012709:Serum Albumin; D002443:Ceftriaxone; D010458:Peptidyl Transferases; D006602:Hexosyltransferases; D002267:Muramoylpentapeptide Carboxypeptidase; D002439:Cefotaxime