title: [Reversible posterior leukoencephalopathy, severe hypertension, and cocaine abuse].
abstract: Reversible posterior leukoencephalopathy syndrome is a brain disorder characterized by headache, nausea, vomiting, visual disturbance, depressed level of consciousness, convulsions and occasionally focal neurologic deficits. It is commonly associated with malignant hypertension, toxemia of pregnancy or the use of immunosuppressive agents. Early diagnosis and specific treatment is essential. We report a case of reversible posterior leukoencephalopathy in the context of a hypertensive crisis in an habitual cocaine sniffer. Reversible posterior leukoencephalopathy must be suspected in every patient with hypertensive crisis and compatible clinic manifestation. Neuroimaging studies show characteristic features which confirm the diagnosis.
authors.affiliation: Sección de Nefrología, Hospital Juan Ramón Jiménez, 21005 Huelva.
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez Gómez
authors.forename: F J
authors.initials: FJ
authors.lastname: Rodríguez Gómez
authors.forename: M J
authors.initials: MJ
authors.lastname: Merino
authors.forename: A
authors.initials: A
authors.lastname: Robledo
authors.forename: J M
authors.initials: JM
authors.lastname: López Domínguez
authors.forename: F
authors.initials: F
authors.lastname: Fernández Girón
authors.forename: J
authors.initials: J
authors.lastname: González Martínez
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001929:Brain Edema / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D003042:Cocaine / Q000008:administration & dosage; D019970:Cocaine-Related Disorders / Q000150:complications*; D004359:Drug Therapy, Combination; D005188:False Negative Reactions; D006261:Headache / Q000209:etiology; D006801:Humans; D006974:Hypertension, Malignant / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D009325:Nausea / Q000209:etiology; D010211:Papilledema / Q000209:etiology; D012907:Smoking; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000209:etiology
chemical_list: D000959:Antihypertensive Agents; D003042:Cocaine