ER export: public transportation by the COPII coach.
The COPII coat produces ER-derived transport vesicles. Recent findings suggest that the COPII coat is a highly dynamic polymer and that efficient capture of cargo molecules into COPII vesicles depends on several parameters, including export signals, membrane environment, metabolic control and the presence of a repertoire of COPII subunit homologues.
Antonny
B
B
Institut de Pharmacologie Moléculaire et Cellulaire, CNRS, 660 route des Lucioles, 06560, Valbonne, France. antonny@ipmc.cnrs.fr
Schekman
R
R
D000818:Animals; D022181:COP-Coated Vesicles / Q000737:chemistry / Q000378:metabolism* / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000502:physiology* / Q000648:ultrastructure; D008954:Models, Biological; D021381:Protein Transport