The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme endonuclease III.
Hashimoto
M
M
Greenberg
M M
MM
Kow
Y W
YW
Hwang
J T
JT
Cunningham
R P
RP
D000903:Antibiotics, Antineoplastic / Q000633:toxicity; D003432:Cross-Linking Reagents / Q000633:toxicity*; D004247:DNA / Q000378:metabolism*; D004249:DNA Damage; D004260:DNA Repair; D043224:Deoxyribonuclease (Pyrimidine Dimer); D004706:Endodeoxyribonucleases / Q000378:metabolism*; D029968:Escherichia coli Proteins; D013400:Sugar Acids / Q000378:metabolism*; D009353:Zinostatin / Q000633:toxicity*
D000903:Antibiotics, Antineoplastic; D003432:Cross-Linking Reagents; D029968:Escherichia coli Proteins; D013400:Sugar Acids; C056405:2,4,5-trihydroxypentanoic acid gamma-lactone; D004247:DNA; D009353:Zinostatin; D004706:Endodeoxyribonucleases; D043224:Deoxyribonuclease (Pyrimidine Dimer); C106403:NTH protein, E coli