title: Casein kinase I: from obscurity to center stage.
abstract: The casein kinase I (CKI) family of protein kinases is a group of highly related, ubiquitously expressed serine/threonine kinases found in all eukaryotic organisms from protozoa to man. Recent advances in diverse fields, including developmental biology and chronobiology, have elucidated roles for CKI in regulating critical processes such as Wnt signaling, circadian rhythm, nuclear import, and Alzheimer's disease progression.
authors.affiliation: Department of Pediatrics and Oncological Sciences, Huntsman Cancer Institute Center for Children, University of Utah, Salt Lake City 84112, USA.
authors.forename: E
authors.initials: E
authors.lastname: Vielhaber
authors.forename: D M
authors.initials: DM
authors.lastname: Virshup
mesh_terms: D000544:Alzheimer Disease / Q000473:pathology; D000818:Animals; D047388:Casein Kinases; D002940:Circadian Rhythm / Q000502:physiology; D018450:Disease Progression; D006801:Humans; D011494:Protein Kinases / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D021381:Protein Transport / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D051153:Wnt Proteins; D029961:Zebrafish Proteins
chemical_list: D011518:Proto-Oncogene Proteins; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D011494:Protein Kinases; D047388:Casein Kinases