Cytokines: IL-20 - a new effector in skin inflammation.
The newly discovered cytokine interleukin-20 (IL-20) is structurally related to IL-10, yet it appears to be an autocrine factor for keratinocytes that regulates their participation in inflammation.
Rich
B E
BE
Harvard Skin Disease Research Center, Brigham and Women's Hospital, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA. brich@rics.bwh.harvard.edu
Kupper
T S
TS
D000818:Animals; D002454:Cell Differentiation; D002455:Cell Division; D004817:Epidermis / Q000276:immunology / Q000502:physiology; D016753:Interleukin-10 / Q000235:genetics; D007378:Interleukins / Q000502:physiology*; D015603:Keratinocytes / Q000276:immunology; D051379:Mice; D008822:Mice, Transgenic; D018448:Models, Immunological; D011565:Psoriasis / Q000276:immunology*; D018123:Receptors, Interleukin / Q000096:biosynthesis; D012867:Skin / Q000276:immunology; D015854:Up-Regulation
D007378:Interleukins; D018123:Receptors, Interleukin; D016753:Interleukin-10; C422042:interleukin 20