The Edinburgh Mouse Atlas: using the CD.
This paper provides a simple introduction to the reconstructions and data-handling tools stored on the Edinburgh Mouse Atlas CD, together with some of the ways in which the viewers and software can be used to understand mouse development and analyse data. The key aspect of the Mouse Atlas is that the underlying models are a complete representation of the histology, which has not been constrained to a particular interpretation. This means, for example, that the current anatomy domains can be further subdivided as required to any resolution up to the resolution of the models (2-7 microm). In the CD of the early embryos described here, virtually all tissues that can be usefully distinguished either by the histology or morphologically have been delineated.
Baldock
R
R
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK. richard@hgu.mrc.ac.uk
Bard
J
J
Brune
R
R
Hill
B
B
Kaufman
M
M
Opstad
K
K
Smith
D
D
Stark
M
M
Waterhouse
A
A
Yang
Y
Y
Davidson
D
D
D000818:Animals; D019295:Computational Biology; D003196:Computer Graphics; D016208:Databases, Factual; D016678:Genome; D007091:Image Processing, Computer-Assisted; D051379:Mice / Q000033:anatomy & histology / Q000196:embryology* / Q000235:genetics; D008953:Models, Anatomic; D012984:Software