Evaluation of antitumor activity of some medicinal plants of Bangladesh by potato disk bioassay.
The antitumor activity of the ethanolic extracts of 12 medicinal plants of Bangladesh, including the vincristine-vinblastine producing Catharanthus roseus was studied using the potato disk bioassay technique. Among these, 10 plant extracts at 25.0-microgram/disc exhibited significant inhibition of crown gall tumors caused by Agrobacterium tumefaciens.
Haque
N
N
Department of Pharmacology, Bangabandhu Seikh Mujib Medical University, Dhaka-1000, Bangladesh.
Chowdhury
S A
SA
Nutan
M T
MT
Rahman
G M
GM
Rahman
K M
KM
Rashid
M A
MA
D016960:Agrobacterium tumefaciens / Q000187:drug effects*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D001459:Bangladesh; D006801:Humans; D008519:Medicine, Traditional; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology; D010941:Plant Tumors; D010946:Plants, Medicinal; D011198:Solanum tuberosum; D014747:Vinblastine / Q000494:pharmacology; D014750:Vincristine / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D014750:Vincristine; D014747:Vinblastine