Childhood Guillain-Barré syndrome: clinical and electrophysiologic features predictive of outcome.
The hospital records of 27 children with the diagnosis of Guillain-Barré syndrome were retrospectively reviewed. Based on the time to recovery, patients were divided into two groups: group 1 consisted of children whose times to complete or partial recovery extended beyond 2 months from onset of the disease; group 2 consisted of children who attained a full recovery within 2 months from onset of the disease. The clinical and electrophysiologic features of the two groups were statistically compared for their predictive value of outcome. Three clinical features (maximum disability score at presentation, intubation, and cranial nerve involvement) were predictive of poor outcome, whereas one electrophysiologic feature (conduction block) was predictive of favorable outcome. There was also a significant correlation between maximum disability score at presentation and the probability of intubation.
Ammache
Z
Z
Department of Neurology, College of Medicine, University of Iowa Hospitals and Clinics, Iowa City 52242, USA. zammache@yahoo.com
Afifi
A K
AK
Brown
C K
CK
Kimura
J
J
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019988:Children with Disabilities; D004594:Electrophysiology; D005260:Female; D020275:Guillain-Barre Syndrome / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009431:Neural Conduction; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index