The effects of vagotomy on the abomasum in calves: radiography and protein gene product 9.5 immunohistochemistry.
Abomasal disorders of calves with total vagotomy, operated on at 1 week old, were investigated with radiography and protein gene product (PGP) 9.5 immunohistochemistry. Radiographic findings indicated abomasal atony with dilatation in all calves 2 weeks after vagotomy, while 4 weeks after vagotomy abomasal dilatation was detected in 2 calves and another 2 calves showed dilatation and impaction. The densities of PGP 9.5-immunoreactive nerves in the tunica muscularis decreased significantly in the corpus region of the greater curvature 2 weeks after vagotomy and in the pyloric region of the lesser curvature 4 weeks after vagotomy, and it was at its lowest 4 weeks after vagotomy in all regions examined. In conclusion, abomasal dilatation and/or impaction in vagotomized calves confirmed by radiography were related with a decreased frequency of nerves in the tunica muscularis of the abomasum.
Soehartono
R H
RH
Department of Veterinary Surgery, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Japan.
Yamada
H
H
Yamagishi
N
N
Kitamura
N
N
Taguchi
K
K
D000018:Abomasum / Q000000981:diagnostic imaging / Q000201:enzymology / Q000294:innervation* / Q000473:pathology; D000818:Animals; D001466:Barium Sulfate / Q000737:chemistry; D002417:Cattle; D002418:Cattle Diseases / Q000201:enzymology / Q000209:etiology* / Q000601:surgery; D003287:Contrast Media / Q000737:chemistry; D005260:Female; D005767:Gastrointestinal Diseases / Q000201:enzymology / Q000209:etiology / Q000601:surgery / Q000662:veterinary*; D006651:Histocytochemistry / Q000662:veterinary; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011859:Radiography; D013869:Thiolester Hydrolases / Q000378:metabolism*; D043222:Ubiquitin Thiolesterase; D014628:Vagotomy / Q000009:adverse effects / Q000662:veterinary*
D003287:Contrast Media; D009419:Nerve Tissue Proteins; D001466:Barium Sulfate; D013869:Thiolester Hydrolases; D043222:Ubiquitin Thiolesterase