title: Activation of caspase-3/caspase-3-like activity in rat cardiomyocytes by an RGD peptide, but not the GPIIb/IIIa antagonist lotrafiban.
authors.affiliation: Department of Cardiovascular Pharmacology, GlaxoSmithKline, King of Prussia, PA 19406, USA. joseph_a_erhardt@sbphrd.com
authors.forename: J A
authors.initials: JA
authors.lastname: Erhardt
authors.forename: E H
authors.initials: EH
authors.lastname: Ohlstein
authors.forename: J R
authors.initials: JR
authors.lastname: Toomey
authors.forename: M A
authors.initials: MA
authors.lastname: Gabriel
authors.forename: R N
authors.initials: RN
authors.lastname: Willette
authors.forename: T L
authors.initials: TL
authors.lastname: Yue
authors.forename: F C
authors.initials: FC
authors.lastname: Barone
authors.forename: A A
authors.initials: AA
authors.lastname: Parsons
mesh_terms: D000818:Animals; D001569:Benzodiazepines; D053148:Caspase 3; D020169:Caspases / Q000378:metabolism*; D002478:Cells, Cultured / Q000187:drug effects; D003374:Coumarins / Q000378:metabolism; D004789:Enzyme Activation; D005343:Fibrinolytic Agents / Q000494:pharmacology* / Q000633:toxicity; D006321:Heart / Q000187:drug effects*; D009206:Myocardium / Q000166:cytology / Q000201:enzymology*; D009842:Oligopeptides / Q000378:metabolism / Q000494:pharmacology*; D010880:Piperidines; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology* / Q000633:toxicity; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D003374:Coumarins; D005343:Fibrinolytic Agents; D009842:Oligopeptides; D010880:Piperidines; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; C102580:acetyl-aspartyl-glutamyl-valyl-aspartyl-amino-4-methylcoumarin; D001569:Benzodiazepines; C046617:arginyl-glycyl-aspartyl-serine; C505410:Casp3 protein, rat; D053148:Caspase 3; D020169:Caspases; C412702:lotrafiban