title: [Hepatobiliary cystic tumors. Clinical, radiological and histopathological study of 7 cases].
abstract: OBJECTIVE
  Hepatobiliary cystic tumors are rare, but must be correctly diagnosed because of their potential malignancy. We report the clinical, radiological, pathological and evolutive characteristics of 7 cases of hepatobiliary cystic tumors.
  
  
  METHODS
  Complete clinical charts were available. Radiological and pathological documents were reviewed.
  
  
  RESULTS
  There were 4 females and 3 males (median age, 58.7 yrs). In 3 cases, the presenting symptom was the palpation of a mass in the right upper abdominal quadrant. In 6 cases, pre-operative imaging studies showed a cystic intra-hepatic mass, containing vegetations and/or septa in 5 cases. In the remaining case, the radiological appearance showed a heterogeneous liver mass. Two patients were treated by pericystectomy and 5 by radical hepatectomy. At macroscopic examination, tumors were usually large (range: 2-24 cm) and multilocular. Histological diagnosis was: cystadenoma with mesenchymous stroma (2 cases), mucinous cystadenoma (2 cases), mucinous cystadenocarcinoma (2 cases), giant cell cystadenocarcinoma (1 case). The mean duration of follow up was 60 months. Two patients, both with cystadenocarcinomas, died after respectively, 21 and 34 months with metastatic dissemination. Five patients are alive without evidence of disease after a delay ranging from 14 to 144 months.
  
  
  CONCLUSIONS
  Radical surgical treatment of cystic hepatobiliary tumors is necessary to obtain histopathological examination of the complete specimen, which is essential for a correct evaluation of the malignant potential of the lesion, and for prolonged survival, even in cases of locally invasive tumors.
authors.affiliation: Fédération des Spécialités Digestives, Hôpital Edouard-Herriot, Lyon, France.
authors.forename: P
authors.initials: P
authors.lastname: Owono
authors.forename: J Y
authors.initials: JY
authors.lastname: Scoazec
authors.forename: P J
authors.initials: PJ
authors.lastname: Valette
authors.forename: J
authors.initials: J
authors.lastname: Dumortier
authors.forename: G
authors.initials: G
authors.lastname: Gouysse
authors.forename: F
authors.initials: F
authors.lastname: Berger
authors.forename: J
authors.initials: J
authors.lastname: Boulez
authors.forename: C
authors.initials: C
authors.lastname: Partensky
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001653:Bile Ducts, Intrahepatic / Q000473:pathology; D002758:Cholangiography; D003536:Cystadenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003537:Cystadenoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010173:Palpation; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D007633:Keratins