Wnt signaling: the naked truth?
Frizzled receptors can activate two alternative signal transduction pathways: the canonical Wnt pathway or the planar cell polarity pathway. Recent studies of the Naked cuticle protein suggest a mechanism for the inactivation of the canonical pathway and concomitant activation of the planar cell polarity pathway.
McEwen
D G
DG
Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, 27599-3280, USA. mcewen@email.unc.edu
Peifer
M
M
D000818:Animals; D019521:Body Patterning; D029721:Drosophila Proteins; D019476:Insect Proteins / Q000502:physiology*; D008954:Models, Biological; D011518:Proto-Oncogene Proteins / Q000037:antagonists & inhibitors* / Q000502:physiology; D015398:Signal Transduction; D051153:Wnt Proteins; D029961:Zebrafish Proteins
D029721:Drosophila Proteins; D019476:Insect Proteins; D011518:Proto-Oncogene Proteins; D051153:Wnt Proteins; D029961:Zebrafish Proteins; C405336:nkd protein, Drosophila