title: Dural arteriovenous fistula associated with prothrombin gene mutation.
abstract: An association between dural arteriovenous fistula and cerebral sinus thrombosis is reported. It is clear in several cases that thrombosis precedes the development of the fistula while it is unclear that it occurs in every case. The authors report a case of a woman with sinus thrombosis and presence of prothrombin gene mutation who subsequently developed a large dural arteriovenous fistula. Various possible factors involved in the pathogenesis of a dural fistula are discussed, with emphasis on underlying thrombophilia and oral contraceptive use in this patient.
authors.affiliation: Department of Neurology, Box 0114, University of California, San Francisco, 505 Parnassus Avenue, M-798, San Francisco, CA 94143-0114, USA. vineeta.singh@ucsfmedctr.org
authors.forename: V
authors.initials: V
authors.lastname: Singh
authors.forename: P M
authors.initials: PM
authors.lastname: Meyers
authors.forename: V H
authors.initials: VH
authors.lastname: Halbach
authors.forename: D R
authors.initials: DR
authors.lastname: Gress
authors.forename: R T
authors.initials: RT
authors.lastname: Higashida
authors.forename: C F
authors.initials: CF
authors.lastname: Dowd
authors.forename: W S
authors.initials: WS
authors.lastname: Smith
mesh_terms: D000328:Adult; D001164:Arteriovenous Fistula / Q000209:etiology*; D003276:Contraceptives, Oral; D004388:Dura Mater; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009154:Mutation; D011516:Prothrombin / Q000235:genetics*; D012851:Sinus Thrombosis, Intracranial / Q000150:complications* / Q000235:genetics / Q000601:surgery
chemical_list: D003276:Contraceptives, Oral; D011516:Prothrombin