title: Sphenoid sinusitis caused by Clostridium perfringens.
abstract: Anaerobic bacterial infections in chronic sinusitis are well described in literature. We present what is believed to be the first reported case of Clostridium perfringens presenting as the causative pathogen in paranasal sinusitis. This patient presented with severe headaches and, with CT and MRI findings of unilateral sphenoid sinus opacification, with bone demineralization and intrasinus calcification. This patient responded to endoscopic debridement and long-term antibiotics without sequelae.
authors.affiliation: Missouri Baptist Medical Center (affiliated with Barnes-Jewish-Christian Hospitals), St. Louis, USA. BNRosenblum@MSN.com
authors.forename: B N
authors.initials: BN
authors.lastname: Rosenblum
authors.forename: M
authors.initials: M
authors.lastname: Gutwein
authors.forename: M F
authors.initials: MF
authors.lastname: Bartell
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003015:Clostridium Infections / Q000175:diagnosis* / Q000628:therapy*; D003016:Clostridium perfringens / Q000302:isolation & purification*; D003131:Combined Modality Therapy; D004724:Endoscopy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D015524:Sphenoid Sinusitis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents