Simple approach to predict the maximal effect elicited by a drug when plasma concentrations are not available or are dissociated from the effect, as illustrated with chondroitin sulfate data.
du Souich
P
P
Department of Pharmacology, Faculty of Medicine, University of Montreal, Canada. patrick.du.souich@umontreal.ca
Vergés
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D002809:Chondroitin Sulfates / Q000097:blood / Q000493:pharmacokinetics / Q000494:pharmacology*; D004008:Diclofenac / Q000494:pharmacology; D006207:Half-Life; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy; D011237:Predictive Value of Tests; D013223:Statistics as Topic; D013997:Time Factors
D004008:Diclofenac; D002809:Chondroitin Sulfates