Microchip electrophoretic separation systems for biomedical and pharmaceutical analysis.
The application of microchip capillary electrophoresis (CE) systems to biomedical and pharmaceutical analysis is described and reviewed. Fabrication, instrumentation, and operation of the systems are discussed. An overview of applications is presented, covering four main areas: DNA sequencing, genetic analysis, immunoassays, and protein and peptide analysis. These systems have the potential to dramatically change the way that biochemical analyses are performed.
Gawron
A J
AJ
Department of Pharmaceutical Chemistry and Center for Bioanalytical Research, University of Kansas, 2095 Constant Avenue, 66047, Lawrence, KS, USA.
Martin
R S
RS
Lunte
S M
SM
D000818:Animals; D020811:Biomedical Technology; D002626:Chemistry, Pharmaceutical / Q000295:instrumentation*; D004586:Electrophoresis / Q000295:instrumentation*; D006801:Humans; D008838:Microcomputers; D004364:Pharmaceutical Preparations / Q000032:analysis*
D004364:Pharmaceutical Preparations