title: Effect of cardiopulmonary bypass on a patient with endocarditis and malaria.
abstract: Knowledge about the effects of cardiopulmonary bypass on malarial patients is scant. Malaria-induced hemolysis can exercerbate by performing extracorporeal circulation on a patient infected with Plasmodium and may, therefore, lead to a critical hemolysis jeopardizing the clinical outcome. A 52-year-old patient suffering from malaria and endocarditis was scheduled for urgent aortic valve replacement. During extracorporeal circulation, free hemoglobin showed an increase to maximum of 392.5 mg/L (normal range < 50 mg/L), while haptoglobin decreased to the lowest value of 0.56 g/L (normal range 0.3-2.0 gL). Although hemolysis increased, pump run, weaning, and the postoperative course were uneventful.
authors.affiliation: Department of Cardiac Surgery, University of Lübeck, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Gerdes
authors.forename: E
authors.initials: E
authors.lastname: Joubert-Hübner
authors.forename: H H
authors.initials: HH
authors.lastname: Sievers
mesh_terms: D001021:Aortic Valve; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D004696:Endocarditis / Q000150:complications*; D005858:Germany; D006350:Heart Valve Prosthesis; D006801:Humans; D016780:Malaria, Vivax / Q000150:complications*; D008297:Male; D008875:Middle Aged; D019616:Thoracic Surgical Procedures