title: New DNA sequencing methods.
abstract: The Human Genome Project and other major genomic sequencing projects have pushed the development of sequencing technology. In the past six years alone, instrument throughput has increased 15-fold. New technologies are now on the horizon that could yield massive increases in our capacity for de novo DNA sequencing. This review presents a summary of state-of-the-art technologies for genomic sequencing and describes technologies that may be candidates for the next generation of DNA sequencing instruments.
authors.affiliation: Department of Physics and Astronomy, 6224 Agricultural Road, University of British Columbia, Vancouver, BC, Canada, V6T-1Z1. andre@physics.ubc.ca
authors.forename: A
authors.initials: A
authors.lastname: Marziali
authors.forename: M
authors.initials: M
authors.lastname: Akeson
mesh_terms: D001698:Biomedical Engineering / Q000379:methods / Q000639:trends; D002197:Capillary Action; D004247:DNA / Q000737:chemistry / Q000235:genetics; D016045:Human Genome Project; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D017422:Sequence Analysis, DNA / Q000379:methods*
chemical_list: D004247:DNA