title: Coexistence of Graves' disease and struma ovarii: case report and literature review.
abstract: We report a rare case of Graves' disease associated with struma ovarii. A 26-year-old Japanese woman had preexisting Graves' disease and was positive for TSH receptor antibody. She had been on antithyroid medication at presentation. She noted a mass in the lower left abdomen, which was diagnosed as a left struma ovarii by radiological work-up including computed tomography, magnetic resonance imaging and scintigraphy. The surgically excised teratomatous tumor, containing cystic spaces with thyroid tissue, was histologically proved to be struma ovarii. Since thyroid function tests and TSH receptor antibody did not change after surgery, her hyperthyroidism was considered to be due to Graves' disease. Our case was diagnosed as struma ovarii before surgery using various imaging studies.
authors.affiliation: Faculty of Education, Okayama University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Mimura
authors.forename: M
authors.initials: M
authors.lastname: Kishida
authors.forename: H
authors.initials: H
authors.lastname: Masuyama
authors.forename: N
authors.initials: N
authors.lastname: Suwaki
authors.forename: J
authors.initials: J
authors.lastname: Kodama
authors.forename: F
authors.initials: F
authors.lastname: Otsuka
authors.forename: H
authors.initials: H
authors.lastname: Kataoka
authors.forename: T
authors.initials: T
authors.lastname: Yamauchi
authors.forename: T
authors.initials: T
authors.lastname: Ogura
authors.forename: T
authors.initials: T
authors.lastname: Kudo
authors.forename: H
authors.initials: H
authors.lastname: Makino
mesh_terms: D000328:Adult; D013956:Antithyroid Agents / Q000627:therapeutic use; D001323:Autoantibodies / Q000097:blood; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D018828:Immunoglobulins, Thyroid-Stimulating / Q000097:blood; D008279:Magnetic Resonance Imaging; D008713:Methimazole / Q000627:therapeutic use; D010051:Ovarian Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D010052:Ovariectomy; D011877:Radionuclide Imaging; D011989:Receptors, Thyrotropin / Q000097:blood; D013330:Struma Ovarii / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D013963:Thyroid Hormones / Q000097:blood; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D013956:Antithyroid Agents; D001323:Autoantibodies; D018828:Immunoglobulins, Thyroid-Stimulating; D011989:Receptors, Thyrotropin; D013963:Thyroid Hormones; C094372:thyrotropin-binding inhibitory immunoglobulin; D008713:Methimazole