Rapid measurement of aortic wave velocity: in vivo evaluation.
A 1D MR sequence has been developed for determining aortic flow wave velocity (WV), a metric of arterial compliance, within a single cardiac cycle. Studies were carried out on the thoracic aortas of 10 normal volunteers. Correlative WV data were also acquired from each subject using a conventional phase-velocity 2D mapping technique. Aortic WV in this cohort was found to range from 411 to 714 cm/s and was highly correlated (R = 0.95) between the two methods. Peak blood velocity was also measured using both methods and found to agree closely. The reproducibility of WV measurements using the rapid 1D method averaged 7.6%, which is comparable or better than that achieved using existing noninvasive techniques. Magn Reson Med 46:95-102, 2001.
Kraft
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Department of Radiology, Virginia Commonwealth University, 1101 East Marshall St., Richmond, VA 23298-0072, USA. kkraft@hsc.vcu.edu
Itskovich
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Fei
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D000328:Adult; D001013:Aorta, Thoracic / Q000033:anatomy & histology / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D015203:Reproducibility of Results; D013997:Time Factors