title: [Resection of malignant tumors involving the anterior cranial fossa].
abstract: BACKGROUND
  The craniofacial approach has greatly facilitated resections of tumours involving the base of the anterior cranial fossa when compared to either the transcranial or transfacial approach alone.
  
  
  METHODS
  This approach was used in 11 patients with malignant tumours localized to the ethmoid sinus, orbit and bone or soft tissue of the base of the anterior part of the skull. By combining a low frontal or frontolateral craniotomy with resection of the facial skull, en bloc resections were accomplished. A frontogaleal periostal flap or a muscle flap from the temporal muscle was used to replace resected bone and to seal the skull base.
  
  
  RESULTS
  There were no peri- or postoperative deaths. One patient died due to local recurrence, one patient is alive with residual tumour six years after surgery, and one is reoperated due to local recurrence. In addition one patient developed recurrence of a previously treated tumour of the maxillary sinus. Two patients developed meningitis and one pneumocephalus postoperatively. One patient has partial loss of vision and two patients underwent dacryocystorhinostomy due to epiphora.
  
  
  CONCLUSIONS
  The planning and execution of this type of surgery requires close interaction in an interdisciplinary team, in particular between neurosurgeon and head and neck surgeon.
authors.affiliation: Øre-nese-halsavdelingen, Rikshospitalet 0027 Oslo. morten.boysen@rikshospitalet.no
authors.forename: M
authors.initials: M
authors.lastname: Boysen
authors.forename: B
authors.initials: B
authors.lastname: Due-Tønnesen
authors.forename: E
authors.initials: E
authors.lastname: Helseth
authors.forename: I A
authors.initials: IA
authors.lastname: Langmoen
authors.forename: K F
authors.initials: KF
authors.lastname: Lindegaard
authors.forename: W
authors.initials: W
authors.lastname: Sorteberg
authors.forename: S J
authors.initials: SJ
authors.lastname: Bakke
authors.forename: T M
authors.initials: TM
authors.lastname: Aaløkken
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003131:Combined Modality Therapy; D003399:Craniotomy / Q000379:methods*; D005004:Ethmoid Bone / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008488:Medical Illustration; D008875:Middle Aged; D019291:Skull Base / Q000601:surgery*; D019292:Skull Base Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D012888:Skull Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D014057:Tomography, X-Ray Computed