The effect of long-term ethanol feeding on Brucella melitensis infection of rats.
The adverse effects of ethanol on Brucella melitensis have not been studied previously. In this study, a new model of B. melitensis infection was used in the setting of chronic ethanol administration in rats. It was found that the chronically ethanol-receiving rats exposed to B. melitensis infection had significantly greater numbers of B. melitensis in their spleen and liver than the rats in the control group.
Yumuk
Z
Z
Departments of Microbiology and Pharmacology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey.
Ozdemirci
S
S
Erden
B F
BF
Dundar
V
V
D000818:Animals; D017347:Brucella melitensis / Q000187:drug effects*; D002006:Brucellosis / Q000473:pathology*; D004195:Disease Models, Animal; D000431:Ethanol / Q000008:administration & dosage* / Q000009:adverse effects; D008099:Liver / Q000473:pathology; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000473:pathology; D013997:Time Factors
D000431:Ethanol