Asthma, rhinitis and dermatitis triggered by fungal infection: therapeutic effects of terbinafine.
We report 2 atopic patients suffering from tinea unguium caused by Trichophyton rubrum. In addition, both patients had symptoms of allergies: one had perennial rhinoconjunctivitis and bronchial asthma, the other had chronic dermatitis of the face and neck. In both cases, their allergy symptoms improved dramatically during oral therapy with the antifungal agent terbinafine (250 mg/day) and relapsed after its discontinuation.
Hürlimann
A
A
Dermatological Practice, Wetzikon, Switzerland. haut@bluewin.ch
Fäh
J
J
D000284:Administration, Oral; D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001249:Asthma / Q000150:complications*; D017449:Dermatitis, Allergic Contact / Q000150:complications*; D005148:Facial Dermatoses / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use*; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications*; D000077291:Terbinafine; D014008:Tinea Pedis / Q000150:complications / Q000188:drug therapy*; D014249:Trichophyton / Q000302:isolation & purification
D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine