title: ZitB (YbgR), a member of the cation diffusion facilitator family, is an additional zinc transporter in Escherichia coli.
abstract: The Escherichia coli zitB gene encodes a Zn(II) transporter belonging to the cation diffusion facilitator family. ZitB is specifically induced by zinc. ZitB expression on a plasmid rendered zntA-disrupted E. coli cells more resistant to zinc, and the cells exhibited reduced accumulation of (65)Zn, suggesting ZitB-mediated efflux of zinc.
authors.affiliation: Department of Soil, Water, and Environmental Science, University of Arizona, Tucson, AZ 85721, USA.
authors.forename: G
authors.initials: G
authors.lastname: Grass
authors.forename: B
authors.initials: B
authors.lastname: Fan
authors.forename: B P
authors.initials: BP
authors.lastname: Rosen
authors.forename: S
authors.initials: S
authors.lastname: Franke
authors.forename: D H
authors.initials: DH
authors.lastname: Nies
authors.forename: C
authors.initials: C
authors.lastname: Rensing
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology*; D002412:Cations; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D006706:Homeostasis; D008670:Metals / Q000494:pharmacology; D015032:Zinc / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D002352:Carrier Proteins; D002412:Cations; D008670:Metals; C017800:zinc-binding protein; D015032:Zinc