Symptomatic gastrointestinal amyloidosis in an HIV-infected patient.
We report a rare case of symptomatic GI amyloidosis in an HIV-infected patient who ultimately developed uncontrollable upper GI bleeding. Gastric and jejunal biopsies revealed amyloidosis. Although the patient's history suggested the possibility of secondary amyloidosis, immunohistochemical staining together with serum electrophoresis and immunofixation revealed the presence of lambda light chains indicating primary amyloidosis.
Chinnakotla
A K
AK
Department of Internal Medicine, Infectious Diseases, and Pathology, University of Illinois at Chicago, USA.
De Luna
A M
AM
Thew
S T
ST
Anderson
B R
BR
Cantave
I M
IM
D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005767:Gastrointestinal Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000150:complications; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007583:Jejunum / Q000648:ultrastructure; D008875:Middle Aged
D000682:Amyloid; C033048:amyloid protein AR, human