[Integrin alpha-6 in cervix neck squamous cell carcinoma HPV 16/18 positive and negative].
In the present paper we study expression of alpha-6 integrin in normal paraepidermal epithelium, in CIN and in cervical invasive carcinoma HPV 16/18 positive and negative. The results suggest that alpha-6 integrin might be a marker for the evaluation of malignancy of squamous cell carcinoma. There is no correlation between the expression of alpha-6 integrin and the presence of HPV.
Kedzia
W
W
Katedry Ginekologii i Połoznictwa AM w Poznaniu.
Schmidt
M
M
Jasiński
P
P
Spaczyński
M
M
D015703:Antigens, CD / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002278:Carcinoma in Situ / Q000737:chemistry* / Q000473:pathology / Q000821:virology; D002294:Carcinoma, Squamous Cell / Q000737:chemistry* / Q000473:pathology / Q000821:virology; D004279:DNA, Viral / Q000032:analysis; D004268:DNA-Binding Proteins; D004848:Epithelium / Q000737:chemistry; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D039503:Integrin alpha6; D009856:Oncogene Proteins, Viral / Q000032:analysis; D027383:Papillomaviridae / Q000302:isolation & purification*; D012097:Repressor Proteins; D002583:Uterine Cervical Neoplasms / Q000737:chemistry* / Q000473:pathology / Q000821:virology
D015703:Antigens, CD; D014408:Biomarkers, Tumor; D004279:DNA, Viral; D004268:DNA-Binding Proteins; C068651:E6 protein, Human papillomavirus type 16; C052603:E6 protein, Human papillomavirus type 18; D039503:Integrin alpha6; D009856:Oncogene Proteins, Viral; D012097:Repressor Proteins