[Presence of MIR-elements in the complete nucleotide sequence of human chromosome 22].
The location of mammalian interspersed repeats (MIRs) and their density have been determined in the complete nucleotide sequence of human chromosome 22. The approach developed by us has allowed detection of 9675 MIRs at a statistically significant level, which by 15% exceeds the MIR number revealed by all previous approaches. It has been demonstrated that a considerable amount of MIRs missed by the algorithms applied earlier occurs in known DNA sequences of the human genome. The study of the MIR density revealed substantial irregularity of their distribution along the chromosome. The data on the MIRs thus found and the computer program searching for diverged sequences are available by E-mail: katrin2@mail.ru or katrin22@mtu-net.ru.
Korotkov
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Korotkova
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D000465:Algorithms; D002892:Chromosomes, Human, Pair 22; D004247:DNA / Q000235:genetics; D006801:Humans; D012091:Repetitive Sequences, Nucleic Acid
D004247:DNA