Burn-induced linear IgA dermatosis.
There have been several reports of linear IgA dermatosis (LAD) associated with drug exposure and lymphoproliferative malignancy, but trauma and burns have been suggested only in patients with bullous pemphigoid. We present a case of burn-induced LAD in a 48-year-old caucasian male presenting with a recent history of blistering eruption on the periphery of a cicatricial area caused by boiling methyl alcohol. Clinically, he presented a widespread bullous eruption. The direct immunofluorescence examination of a perilesional biopsy revealed an intense homogeneous linear pattern of IgA deposition consistent with the diagnosis of LAD. The patient responded to therapy with systemic steroids.
Girão
L
L
Dermatology Department, Desterro Hospital, Lisbon, Portugal. leonogirao@net.sapo.pt
Fiadeiro
T
T
Rodrigues
J C
JC
D000284:Administration, Oral; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D001707:Biopsy, Needle; D002057:Burns, Chemical / Q000150:complications*; D002921:Cicatrix / Q000150:complications; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007150:Immunohistochemistry; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D016896:Treatment Outcome
D000888:Antibodies, Anti-Idiotypic; D007070:Immunoglobulin A; D008775:Methylprednisolone