title: Effect of low-dose antigen exposure on development of immunity to Helicobacter pylori infection in mice.
abstract: The effect of low-dose antigen exposure on the development of immunity to Helicobacter pylori infection was studied in outbred mice. Animals that were primed with a subinfectious number of H. pylori bacteria exhibited significantly lower bacterial loads after challenge with an infectious dose of pathogen (versus controls, P < 0.05).
authors.affiliation: Unité de Pathogénie Bactérienne des Muqueuses, Institut Pasteur, Paris 75724, France.
authors.forename: F J
authors.initials: FJ
authors.lastname: Radcliff
authors.forename: R L
authors.initials: RL
authors.lastname: Ferrero
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000276:immunology*; D001426:Bacterial Proteins; D016481:Helicobacter Infections / Q000097:blood / Q000276:immunology* / Q000473:pathology; D016480:Helicobacter pylori / Q000276:immunology*; D007371:Interferon-gamma / Q000032:analysis; D015847:Interleukin-4 / Q000032:analysis; D051379:Mice; D012269:Ribosomal Proteins / Q000276:immunology; D013270:Stomach / Q000382:microbiology / Q000473:pathology
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D012269:Ribosomal Proteins; C048502:ribosomal protein SS1, Streptomyces aureofaciens; D015847:Interleukin-4; D007371:Interferon-gamma