Ulcerative colitis and colonic lymphoma: a theoretical link.
Ulcerative colitis (UC) is an inflammatory disease of the colon and rectum. Although colonic adenocarcinoma is a recognized complication of UC there have been few reported cases of gastrointestinal lymphoma arising in this setting. We describe our experience with such a case and review the literature that attempts to explain possible genetic etiologies for the malignant transformation of gastrointestinal lymphoid tissue to lymphoma as well as a link between UC and lymphoma.
Khan
S
S
Division of Colon and Rectal Surgery, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Anderson
G K
GK
Eppstein
A C
AC
Eggenberger
J C
JC
Margolin
D A
DA
D003093:Colitis, Ulcerative / Q000150:complications*; D003110:Colonic Neoplasms / Q000209:etiology*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors