title: [Reconstruction of the sellar floor during transnasal pituitary surgery using ceramics composed of a combination of hydroxyapatite and tricalciumphosphate].
abstract: Our clinical experience with reconstruction of the sellar floor during transnasal-transsphenoidal surgery for pituitary tumors using ceramics composed of a combination of hydroxyapatite and tricalciumphosphate (pituitary plate) is described. A pituitary plate was used to reconstruct the sellar floor in 15 patients with pituitary tumors that included 13 pituitary adenomas and 2 Rathke's cleft cysts. This method is indicated for cases of reoperation and cases in which there is of much cerebrospinal fluid leakage during surgery. This material is provided as a pituitary plate 12 x 12 mm round and 2 mm thick. There are four holes in the center by which the plate can be held with regular bipolar forceps. At the time of closing the sellar floor window, a pituitary plate was carved with scissors into a suitable shape and slipped inside the bony defect. The postoperative position of the pituitary plate could be clearly identified on skull roentgenogram and magnetic resonance imaging. No displacement or migration of the implanted pituitary plate was observed in any patient during follow-up radiological examinations. Infections such as a pituitary abscess or meningitis were not observed clinically or radiologically in any patient. In three patients who underwent repeated transnasal surgery for regrowth of the tumor, the pituitary plate that had been placed at the initial procedure was covered with a thin fibrous capsule and the plate was well preserved. These results indicate that a pituitary plate can be useful for reconstruction of the sellar floor in transnasal-transsphenoidal surgery.
authors.affiliation: Department of Neurosurgery, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
authors.forename: M
authors.initials: M
authors.lastname: Kushima
mesh_terms: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D002516:Ceramics; D006801:Humans; D006882:Hydroxyapatites; D007016:Hypophysectomy / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012658:Sella Turcica / Q000601:surgery*
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D006882:Hydroxyapatites; C485817:beta-tricalcium phosphate; C018392:tricalcium phosphate