title: [Usefulness of enzyme tests, biochemical tests and ultrasonography for evaluation of hepatotoxic impact of ethanol].
abstract: The aim of this study was to evaluate the morphological and functional status of the liver in alcoholics using ultrasonography, measurements of chosen enzymes activity and biochemical parameters. The attempt to estimate the dependence of the frequency and intensification of the liver lesion on the controlled abstinence period was also made in this study. Under examination there were 30 ethanol dependent patients, poisoned with ethanol, treated at the Department of Toxicology. In order to detect the dynamics of liver lesion all patients underwent second examination after 3 weeks of a controlled abstinence. The reference group comprised 30 healthy men, not exposed to hepatotoxic agents. The liver ultrasonography combined with biochemical analysis allows to assess the liver condition in alcoholics poisoned with ethanol.
authors.affiliation: Klinika Toksykologii KPMiCHS Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
authors.forename: I
authors.initials: I
authors.lastname: Wegrzynek
authors.forename: E
authors.initials: E
authors.lastname: Zulikowska
mesh_terms: D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000032:analysis; D000437:Alcoholism / Q000150:complications*; D000469:Alkaline Phosphatase / Q000032:analysis; D001219:Aspartate Aminotransferases / Q000032:analysis; D004796:Clinical Enzyme Tests; D006519:Hepatitis, Alcoholic / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000201:enzymology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography; D005723:gamma-Glutamyltransferase / Q000032:analysis
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase