Sudan: the possible original focus of visceral leishmaniasis.
Fifty-two Leishmania strains, obtained from human patients and dogs in a visceral leishmaniasis focus in Sudan, were characterized by isoenzyme electrophoresis (15 enzymes). The phylogenetic analysis showed that the 7 Leishmania zymodemes obtained hold ancestral positions on the phylogenetic tree, supporting the hypothesis of an East African origin of visceral leishmaniasis.
Pratlong
F
F
Laboratoire de Parasitologie et Centre National de Reference des Leishmanioses, CHU de Montpellier, France.
Dereure
J
J
Bucheton
B
B
El-Saf
S
S
Dessein
A
A
Lanotte
G
G
Dedet
J P
JP
D000818:Animals; D004285:Dogs; D004592:Electrophoresis, Starch Gel; D006801:Humans; D007527:Isoenzymes / Q000235:genetics; D007891:Leishmania / Q000145:classification* / Q000201:enzymology* / Q000235:genetics; D007898:Leishmaniasis, Visceral / Q000453:epidemiology* / Q000469:parasitology; D010802:Phylogeny; D013397:Sudan / Q000453:epidemiology
D007527:Isoenzymes