title: Effect of altitude training on the peroxidation and antioxidant enzymes in sportsmen.
abstract: OBJECTIVE
  The aim of this work was an evaluation of the influence of physical exercise in high-altitude conditions (about 2000 m above sea level) on thiobarbituric acid reactive substances (TBARS) and superoxide dismutase (SOD) and catalase (CAT) activities in 10 kayakers and 10 rowers.
  
  
  METHODS
  During their training, the sportsmen performed different kinds of static and dynamic efforts. The blood samples were taken from the cubital vein on the control day at low altitude and at high altitude, and on the 4th, 10th, and 18th days of the training camp before and after exercise. The TBARS and lactic acid concentrations in blood plasma and SOD and CAT activities in erythrocytes were measured.
  
  
  RESULTS
  A statistically significant increase of SOD and CAT activities in erythrocytes after exercise on the 4th, 10th, and 18th days of training was found. The TBARS concentration in erythrocytes decreased in a statistically significant way after the end of the 10th day of exercise (P < 0.01), and on 18th day it more than doubled (P < 0.001) when preexercise values were compared with postexercise values of each day. A statistically significant increase of TBARS concentration in blood plasma was observed only after the end of exercise on the 10th day-using the same comparison as above. A statistically significant increased lactic acid concentration in blood plasma was noticed both on 4th or 18th days of training.
  
  
  CONCLUSIONS
  The results obtained show the increasing generation of oxygen-derived free radicals and the compensatory intensification of SOD and CAT activities after training in altitude (high mountain) conditions.
authors.affiliation: Departments of Biology and Physiology, Ludwik Rydygier Medical University, Military Sports Centre, PMR, Bydgoszcz, Poland. bartoszw@poczta.wp.pl
authors.forename: A
authors.initials: A
authors.lastname: Wozniak
authors.forename: G
authors.initials: G
authors.lastname: Drewa
authors.forename: G
authors.initials: G
authors.lastname: Chesy
authors.forename: A
authors.initials: A
authors.lastname: Rakowski
authors.forename: M
authors.initials: M
authors.lastname: Rozwodowska
authors.forename: D
authors.initials: D
authors.lastname: Olszewska
mesh_terms: D000328:Adult; D000531:Altitude; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D004912:Erythrocytes / Q000201:enzymology; D015444:Exercise / Q000502:physiology*; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D010949:Plasma / Q000201:enzymology; D013177:Sports / Q000502:physiology*; D013482:Superoxide Dismutase / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances; D019344:Lactic Acid; D002374:Catalase; D013482:Superoxide Dismutase