Chelated metal ions for therapeutic and diagnostic applications.
Use of radiolabeled monoclonal antibodies (mAb's) that localize and bind to malignant cells continues to be an attractive mechanism for targeting and delivering either an imagable isotope, be it a y-emitter or B(+)-emitter, or a particle emitter such as a B(-)-emitter or an a-emitter for therapeutic applications.
Brechbiel
M W
MW
Radioimmune & Inorganic Chemistry Section, DCS, NCI, NIH, Bethesda, MD 20892, USA.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D001729:Bismuth; D002614:Chelating Agents; D006801:Humans; D007553:Isotope Labeling; D007554:Isotopes; D008670:Metals; D009369:Neoplasms / Q000175:diagnosis / Q000628:therapy; D004369:Pentetic Acid
D000911:Antibodies, Monoclonal; D002614:Chelating Agents; D007554:Isotopes; D008670:Metals; D004369:Pentetic Acid; D001729:Bismuth