MRA demonstration of "periarteritis" in Tolosa-Hunt syndrome.
BACKGROUND
Modern magnetic resonance imaging (MRI) diagnosis of Tolosa-Hunt syndrome rests upon demonstration of cavernous sinus abnormalities. We present a case of Tolosa-Hunt syndrome who has no abnormal mass lesion in the cavernous sinuses on MRI but with a diagnostic lesion on magnetic resonance angiography (MRA).


METHODS
A 48-year-old woman developed acute periorbital pain and abducens palsy of the right side at the first episode, and subacute peri-orbital pain and rapidly deteriorating visual acuity on the left side at the second episode with a four months interval. MRI showed no soft-tissue abnormality in the cavernous sinuses.


RESULTS
MRA demonstrated a narrowing of the right cavernous carotid artery at the first episode, and narrowings of the left clinoid carotid and ophthalmic arteries at the second episode. Based on these findings, the patient underwent urgent steroid therapy and the symptoms resolved dramatically in each episode. Follow-up MRA confirmed resolution of arterial narrowings.


CONCLUSIONS
MRA may help prompt the noninvasive diagnosis in certain cases of Tolosa-Hunt syndrome with little inflammatory reaction in the cavernous sinus but with predominant intra- and juxta-cavernous periarteritis.
Ozawa
T
T
Department of Neurosurgery, Brain Research Institute, Niigata University, Japan.
Minakawa
T
T
Saito
A
A
Yoneoka
Y
Y
Yoshimura
J
J
Arai
H
H
D002426:Cavernous Sinus / Q000473:pathology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000175:diagnosis*; D011237:Predictive Value of Tests; D020333:Tolosa-Hunt Syndrome / Q000175:diagnosis*