title: The functional anatomy of inhibition processes investigated with the Hayling task.
abstract: The cortical areas involved in inhibition processes were examined with positron emission tomography (PET). The tasks administered to subjects were an adaptation of the Hayling test. In the first condition (response initiation), subjects had to complete sentences with a word clearly suggested by the context, whereas in the second condition (response inhibition), subjects had to produce a word that made no sense in the context of the sentence. Results indicated that the response initiation processes were associated to increases of activity in the left inferior frontal gyrus (BA 45/47), whereas response inhibition processes led to increases in a network of left prefrontal areas, including the middle (BA 9 and BA 10) and inferior (BA 45) frontal areas.
authors.affiliation: Department of Neuropsychology, University of Liège, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Collette
authors.forename: M
authors.initials: M
authors.lastname: Van der Linden
authors.forename: G
authors.initials: G
authors.lastname: Delfiore
authors.forename: C
authors.initials: C
authors.lastname: Degueldre
authors.forename: A
authors.initials: A
authors.lastname: Luxen
authors.forename: E
authors.initials: E
authors.lastname: Salmon
mesh_terms: D000328:Adult; D001288:Attention / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008297:Male; D009415:Nerve Net / Q000000981:diagnostic imaging / Q000502:physiology; D009433:Neural Inhibition / Q000502:physiology*; D017397:Prefrontal Cortex / Q000000981:diagnostic imaging / Q000502:physiology; D011340:Problem Solving / Q000502:physiology*; D011932:Reading; D012016:Reference Values; D012660:Semantics; D014055:Tomography, Emission-Computed; D014706:Verbal Learning / Q000502:physiology