title: Nuclear magnetic resonance-based approaches for lead generation in drug discovery.
authors.affiliation: Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts 02139, USA.
authors.forename: J W
authors.initials: JW
authors.lastname: Peng
authors.forename: C A
authors.initials: CA
authors.lastname: Lepre
authors.forename: J
authors.initials: J
authors.lastname: Fejzo
authors.forename: N
authors.initials: N
authors.lastname: Abdul-Manan
authors.forename: J M
authors.initials: JM
authors.lastname: Moore
mesh_terms: D001665:Binding Sites; D015195:Drug Design; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005461:Fluorine; D008024:Ligands; D046911:Macromolecular Substances; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry; D011522:Protons
chemical_list: D008024:Ligands; D046911:Macromolecular Substances; D011506:Proteins; D011522:Protons; D005461:Fluorine