Cytoskeleton: CLASPing the end to the edge.
Microtubules play a critical role in establishing asymmetry in many cell types. Recent work suggests how conserved protein complexes that bind specifically to the growing ends of microtubules may establish polarized links to special regions of the cell cortex.
McNally
F J
FJ
Section of Molecular and Cellular Biology, University of California at Davis, 95616, USA. fjmcnally@ucdavis.edu
D000818:Animals; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D008954:Models, Biological; D009363:Neoplasm Proteins; D011485:Protein Binding; D020033:Protein Isoforms
C405804:EB1 microtubule binding proteins; D008869:Microtubule-Associated Proteins; D009363:Neoplasm Proteins; D020033:Protein Isoforms; C076744:cytoplasmic linker protein 170