[Iridocorneal endothelial syndrome. Series of 7 cases].
The ICE syndrome includes 3 variants of the same disease, previously believed to be independent entities. All 3 share clinical and histopathological features such as endothelial abnormalities, iris damage, and progressive closure of the iridocorneal angle. Seven cases of ICE syndrome are reported, affecting 6 women and 1 man, with a mean age of 40 years. Corectopia was found in 5 eyes, a uveal ectropion in 2 cases, and other iris changes in 3 cases. The endothelial changes of the cornea were confirmed by a speculum microscopy in 5 cases. There were 5 cases of Chandler syndrome, 1 of Cogan-Reese syndrome, and 1 case of iris essential atrophy in our series. Ocular hypertony was observed in 3 cases, 2 of which needed to be operated. In one patient, a corneal edema was observed.
Halhal
M
M
Service d'ophtalmologie (Pr G. Renard), Hôtel Dieu de Paris, 75181 Paris Cedex 04, France.
D'hermies
F
F
Morel
X
X
Renard
G
G
D000328:Adult; D003315:Cornea / Q000473:pathology; D003316:Corneal Diseases / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D003317:Corneal Dystrophies, Hereditary / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D006801:Humans; D007498:Iris / Q000473:pathology; D008875:Middle Aged; D013577:Syndrome