Effects of Isatis cappadocica on humoral immune responses.
The effects of a 20% ethanol extract of Isatis cappadocica on humoral immune responses in rabbits and mice were studied. After intraperitoneal injection of 0.25 and 0.5 g/kg, a dose-dependent effect was observed. In particular, the dose of 0.25 g/kg suppressed the primary immune responses, while the dose of 0.5 g/kg stimulated the secondary immune responses.
Rezaeipoor
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Immunology Department, Medical School, Shahid Beheshti University of Medical Science, P.O. Box 19835-145, Tehran, Iran. okhravi@khayam.ut.ac.ir
Ziaei Sanei
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Kamalinejad
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M
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D019607:Brassicaceae; D004305:Dose-Response Relationship, Drug; D005260:Female; D006386:Hemagglutination Tests; D007958:Leukocyte Count; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009929:Organ Size / Q000187:drug effects; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology; D010946:Plants, Medicinal; D011817:Rabbits; D013154:Spleen / Q000187:drug effects
D010936:Plant Extracts