title: Measurement of functional residual capacity through the transient phase of He dilution in newborns.
abstract: Helium dilution maneuver is used to determine the functional residual capacity (FRC) 14 newborns ages 1-5 mo. The model equation describes the changing alveolar fractions of He and the ventilation promoted by a rebreathing procedure that does not exceed 40 s. The model does not involve the volume of the rebreathing bag usually needed when applying rebreathing technique and which is a source of error. The equation is discretized and solved for recorded data obtained with equipment adapted to newborns. Results show a strong relationship between FRC and the biometrical indexes, and confirm those found in the literature featuring that the measurement duration of FRC can be considerably shortened.
authors.affiliation: URAPC School of Medicine, Amiens, France. urapc@libertysurf.fr
authors.forename: B
authors.initials: B
authors.lastname: Bouferrache
authors.forename: G
authors.initials: G
authors.lastname: Krim
authors.forename: A
authors.initials: A
authors.lastname: Léké
authors.forename: M
authors.initials: M
authors.lastname: Freville
authors.forename: J P
authors.initials: JP
authors.lastname: Libert
mesh_terms: D001830:Body Surface Area; D003625:Data Collection; D005652:Functional Residual Capacity / Q000502:physiology*; D006371:Helium / Q000493:pharmacokinetics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008954:Models, Biological; D011659:Pulmonary Gas Exchange; D013147:Spirometry
chemical_list: D006371:Helium