title: Spontaneous intracranial hypotension: the value of brain measurements in diagnosis by MRI.
abstract: Caudal brain displacement is inconstantly reported as an MRI feature of spontaneous intracranial hypotension (SIH). We reviewed the clinical data and MRI of eight patients diagnosed as having SIH and investigated the possibility of more precise assessment. On midsagittal images we measured four anatomical landmarks: the position of the cerebellar tonsils, fourth ventricle, and infundibular recess, plus the angle between the bicommissural line and a line tangential to the floor of the fourth ventricle; midsagittal images from 89 normal controls were also measured. On statistical analysis, all measurements differed in the two groups, and the difference was significant for the cerebellar tonsils, fourth ventricle, and infundibular recess. Some overlap between patients and controls was found for each measurement; however, all the patients had two (two patients) or more (six) values outside the range in normal controls range or not above their 1st quartile. Measurement of the position of the third ventricle seemed particularly sensitive. We suggest that examination of midsagittal images can help in diagnosing clinically suspected SIH.
authors.affiliation: Department of Neuroradiology, Facoltà di Medicina, Università degli Studi di Ancona, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Messori
authors.forename: B F
authors.initials: BF
authors.lastname: Simonetti
authors.forename: L
authors.initials: L
authors.lastname: Regnicolo
authors.forename: P
authors.initials: P
authors.lastname: Di Bella
authors.forename: F
authors.initials: F
authors.lastname: Logullo
authors.forename: U
authors.initials: U
authors.lastname: Salvolini
mesh_terms: D000328:Adult; D000886:Anthropometry; D016022:Case-Control Studies; D002531:Cerebellum / Q000033:anatomy & histology* / Q000473:pathology; D002552:Cerebral Ventricles / Q000033:anatomy & histology / Q000473:pathology; D005260:Female; D006801:Humans; D019585:Intracranial Hypotension / Q000175:diagnosis / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies