title: Short course directly observed therapy to monitor compliance with antiretroviral therapy in human immunodeficiency virus-infected children.
abstract: We report our experience with short course directly observed therapy (DOT) in six human immunodeficiency virus-infected children who had a poor response to their prescribed therapy. Four to 8 days of DOT resulted in a significant drop in the viral load of all six children, demonstrating that short course DOT is an effective way to document poor compliance with antiretroviral therapy.
authors.affiliation: Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY, USA.
authors.forename: F
authors.initials: F
authors.lastname: Gigliotti
authors.forename: B L
authors.initials: BL
authors.lastname: Murante
authors.forename: G A
authors.initials: GA
authors.lastname: Weinberg
mesh_terms: D000284:Administration, Oral; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods* / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000523:psychology; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D019380:Anti-HIV Agents