Y2K+1 state-of-the-art on non-peptide phosphoantigens, a novel category of immunostimulatory molecules.
Some human T cells are activated in vivo and in vitro by small non-peptide antigens, so-called phosphoantigens. Since their discovery in 1994, several reports have continuously documented novel members of this category of immunostimulatory molecules. This article reviews the current knowledge on their biochemical properties.
Espinosa
E
E
Inserm U395, CHU Purpan, BP3028, 31024, Toulouse, France.
Belmant
C
C
Sicard
H
H
Poupot
R
R
Bonneville
M
M
Fournié
J J
JJ
D000941:Antigens / Q000737:chemistry / Q000276:immunology*; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology*; D010766:Phosphorylation; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D016692:Receptors, Antigen, T-Cell, gamma-delta