title: Relationship of the cochlear aqueduct and inner ear pressure in Ménière's disease and in a normal population.
abstract: OBJECTIVE
  The aim of this study was to determine the dimensions of cochlear aqueduct radiologically in patients with Ménière's disease and in normal subjects, and to correlate these findings with normal and low static acoustic compliance (SAC) (high and normal perilymphatic pressure) to see whether the dimensions of the cochlear aqueduct play any role in the perilymphatic pressure in normal individuals and patients with Ménière's disease.
  
  
  METHODS
  Prospective double-blind study.
  
  
  METHODS
  The study was conducted at Hacettepe University Medical Faculty, a tertiary care center.
  
  
  METHODS
  Forty patients with Ménière's disease with bilateral involvement, diagnosed by vertigo attacks, fluctuating hearing loss, tinnitus, fullness in the ear, and cochlear sensitivity constituted the patient group. Forty healthy individuals with no otolaryngologic symptoms constituted the control group.
  
  
  METHODS
  All individuals underwent SAC measurement in terms of equivalent volume in milliliters, based on two volume measurements. To measure the dimensions of the cochlear aqueduct, high-resolution computed tomography of the temporal bone in the axial plane was performed.
  
  
  RESULTS
  There was no statistically significant difference in the width of the cochlear aqueduct between patients with Ménière's disease and normal subjects. When SAC measurements were also taken into account, there was no difference in cochlear aqueduct dimensions between individuals with normal and low SAC values in the two groups.
  
  
  CONCLUSIONS
  The dimensions of cochlear aqueduct are not significantly different in Méniére's disease patients and normal individuals. Also, the cochlear aqueduct does not appear to play a significant role in normal and low SAC values in the two groups of individuals.
authors.affiliation: Departments of Otolaryngology Head and Neck Surgery, Hacettepe University Medical Faculty, Ankara, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Yilmazer
authors.forename: L
authors.initials: L
authors.lastname: Sennaroglu
authors.forename: F
authors.initials: F
authors.lastname: Basaran
authors.forename: G
authors.initials: G
authors.lastname: Sennaroglu
mesh_terms: D000293:Adolescent; D000328:Adult; D003052:Cochlear Aqueduct / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis* / Q000503:physiopathology*; D008875:Middle Aged; D010498:Perilymph / Q000502:physiology; D011312:Pressure; D011446:Prospective Studies; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed