title: Saccadic eye movement and visual pathways function in diabetic patients.
abstract: We assessed saccadic eye movements (SEM) and the visual evoked potentials (VEP) with the aim to evaluate whether a correlation exist between SEM and visual pathways function, in insulin-dependent diabetes mellitus (IDDM) patients. In IDDM patients we observed significantly longer SEM latency, while SEM velocity and accuracy were similar to those of the controls; VEP showed a significant delay of the latencies and significant reduction of the amplitudes in IDDM patients no relationship between SEM and VEP parameters were found. In conclusion SEM latency delay suggest an impairment of the saccadic eye movement system, while impaired VEP may be ascribed to a dysfunction of the visual pathways. The lack of correlation between VEP impairment and SEM latency delay suggests that in our IDDM patients the delay of saccadic latency could be ascribed to a difuse neuronal problem exceeding the visual pathways disfunction.
authors.affiliation: Cattedra di Otorinolaringoiatria, Università di Roma Tor Vergata.
authors.forename: M
authors.initials: M
authors.lastname: Alessandrini
authors.forename: E
authors.initials: E
authors.lastname: Bruno
authors.forename: V
authors.initials: V
authors.lastname: Parisi
authors.forename: L
authors.initials: L
authors.lastname: Uccioli
authors.forename: P G
authors.initials: PG
authors.lastname: Giacomini
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D004584:Electronystagmography / Q000379:methods; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D012438:Saccades / Q000502:physiology*; D014795:Visual Pathways / Q000503:physiopathology*