[Effect of antibiotic therapy on embryotropic antibody level in women].
Embriotropic antibodies (e-Ab) serum contents were analysed in 29 serum samples obtained from women suffering with primary lues. Before treatment the content of e-Ab against MBP, S100, ACBP14/18, and MP65 were markedly elevated in 28 samples. Two injections of Retarpen (2.5 mln Units with one week interval) were enough for effective treatment of lues. At the same time treatment caused deep and reversible inhibition of e-Ab production. One or two months later the levels of e-Ab returned to normal values in 21% of women, in 52% patients the hypoproduction, and in 27% the hyperproduction of e-Ab were noted. Deviations of e-Ab production after effective retarpen treatment suggest the existence of additional reasons which may influence e-Ab production, and necessity of additional diagnostic and curative measures for such women during pregravidal period.
Morozov
S G
SG
Municipal Hospital No. 29 Committee for Health, Moscow.
Poletaev
A B
AB
Radzinskiĭ
V E
VE
Protsenko
A N
AN
Korzhenevskiĭ
D A
DA
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000906:Antibodies / Q000097:blood*; D002843:Chromatin / Q000276:immunology*; D005260:Female; D006801:Humans; D008562:Membrane Glycoproteins / Q000276:immunology*; D004676:Myelin Basic Protein / Q000276:immunology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000276:immunology; D009418:S100 Proteins / Q000276:immunology*; D013587:Syphilis / Q000188:drug therapy* / Q000276:immunology
D000900:Anti-Bacterial Agents; D000906:Antibodies; D002843:Chromatin; D008562:Membrane Glycoproteins; D004676:Myelin Basic Protein; D009418:S100 Proteins; C110294:S100A1 protein; C025363:mannoproteins