Platelet adhesion to fibrinogen coated at various densities.
Platelet adhesion to low-density coated fibrinogen induces greater protein tyrosine phosphorylation of SYK and FAK than adhesion to high-density coated fibrinogen, and leads to activation of integrin alpha IIb beta 3 on the luminal side of adherent platelets.
Jirousková
M
M
Mount Sinai School of Medicine, Box 1118, One Gustave L. Levy Place, New York, NY 10029, USA. marketa_jirouskova@mssm.edu
Coller
B S
BS
D001792:Blood Platelets / Q000166:cytology* / Q000378:metabolism; D002448:Cell Adhesion; D005340:Fibrinogen / Q000378:metabolism*; D010766:Phosphorylation; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000378:metabolism; D014443:Tyrosine / Q000378:metabolism
D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D014443:Tyrosine; D005340:Fibrinogen