Novel strategies for intervention targeted at mycobacterial persistence.
Effective global control of tuberculosis is likely to require intervention at multiple points in the course of infection. In addition to existing approaches based on treatment of active disease and preventive vaccination of unexposed individuals, current research on the biology of mycobacterial persistence suggests the potential for the development of novel disease-control strategies targeted at infected asymptomatic populations.
Young
D B
DB
Imperial College School of Medicine, London, UK.
D000818:Animals; D001500:BCG Vaccine / Q000627:therapeutic use*; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D014376:Tuberculosis / Q000382:microbiology / Q000517:prevention & control*
D001500:BCG Vaccine