Evaluation of Binax now Streptococcus pneumoniae urinary antigen test in children in a community with a high carriage rate of pneumococcus.
Pneumococcal antigen was present in urine from 49 of 102 well Gambian children. Eighty-nine of the 102 were nasopharyngeal carriers of pneumococci. The positive predictive value for carriage was 96%, and the negative predictive value was 22%. The test is not useful for predicting etiology of disease in populations with a high rate of nasopharyngeal carriage of pneumococci.
Adegbola
R A
RA
MRC Laboratories, Banjul, The Gambia.
Obaro
S K
SK
Biney
E
E
Greenwood
B M
BM
D000942:Antigens, Bacterial / Q000652:urine*; D002353:Carrier State / Q000652:urine; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000652:urine; D005714:Gambia; D006801:Humans; D009305:Nasopharynx / Q000382:microbiology; D011008:Pneumococcal Infections / Q000175:diagnosis* / Q000276:immunology / Q000652:urine*; D011237:Predictive Value of Tests; D013296:Streptococcus pneumoniae / Q000276:immunology* / Q000302:isolation & purification
D000942:Antigens, Bacterial