[Benign recurrent intrahepatic cholestasis: a seven-year follow-up report].
Benign recurrent intrahepatic cholestasis is a rare autosomal recessive disorder characterized by repeated episodes of intense pruritus and jaundice. Patients are completely asymptomatic for months to years between symptomatic periods. We report a case of a patient with a 7-year history of benign recurrent intrahepatic cholestasis. During the follow-up period the patient has suffered three attacks of cholestasis, confirmed by biochemical tests and histological exam. Liver enzymes were normal between the cholestasis episodes. Despite multiple attacks of cholestasis, no permanent liver damage has occurred. Although the diagnosis of benign recurrent intrahepatic cholestasis is rare, it should be included in the evaluation of a patient with cholestasis. The patients should be reassured of the benign course of this disorder.
Parolin
M B
MB
Serviço de Transplante Hepático, Hospital de Clínicas da Universidade Federal do Paraná-UFPR, Curitiba, PR.
Langowiski
A R
AR
Ioshii
S O
SO
Maggio
E M
EM
Coelho
J C
JC
D000328:Adult; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis* / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012008:Recurrence