Genetic markers for coronary heart disease.
Coronary heart disease (CHD) is a complex disease that is affected by environmental as well as genetic factors. Research is ongoing that probes the relationship of human genetic variation to disease, potentially leading to better diagnosis and therapy. Variation in factors such as low-density lipoprotein cholesterol, apolipoprotein E, high-density lipoprotein cholesterol, apolipoprotein A-I/CIII/A-IV, lipoprotein lipase, cholesteryl ester transfer protein, lipoprotein (a), and homocysteine may affect CHD risk via genetic or environmental mechanisms or their interactions.
Breslow
J L
JL
Rockefeller University, Laboratory of Biochemical Genetics and Metabolism, New York, New York 10021, USA. breslow@mail.rockefeller.edu
D000818:Animals; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003327:Coronary Disease / Q000235:genetics*; D004200:Diseases in Twins; D008040:Genetic Linkage; D014644:Genetic Variation; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D051379:Mice; D012307:Risk Factors
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008074:Lipoproteins