title: Treatment of pyogenic granuloma with a sclerosing agent.
abstract: BACKGROUND
  Pyogenic granulomas have been treated by cryosurgery, curettage, electrodesiccation, chemical cauterization, and laser surgery. The therapeutic effects of these conservative treatments are limited, however.
  
  
  OBJECTIVE
  In this study, the efficacy of a sclerosing agent (monoethanolamine oleate) was evaluated for the treatment of pyogenic granuloma.
  
  
  METHODS
  Pyogenic granuloma was treated by local injection of the monoethanolamine oleate solution in nine patients who were from 1 to 57 years of age (median 18 years). The treatment effect was determined by physical examination.
  
  
  RESULTS
  All lesions were removed completely with no recurrence, and scars were inconspicuous in all cases. Complications occurred in only one patient who complained of pain due to an avoidable injection of excess solution.
  
  
  CONCLUSIONS
  Sclerotherapy with monoethanolamine oleate is effective in the treatment of pyogenic granuloma and offers an alternative to conventional methods in cases for which conservative treatment is preferable.
authors.affiliation: Section of Plastic and Reconstructive Surgery, University Hospital, University of Tokushima, Kuramnoto-cho 2-50-1, Tokushima 770-8503, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
authors.forename: H
authors.initials: H
authors.lastname: Nakanishi
authors.forename: T
authors.initials: T
authors.lastname: Seike
authors.forename: Y
authors.initials: Y
authors.lastname: Koizumi
authors.forename: K
authors.initials: K
authors.lastname: Mihara
authors.forename: Y
authors.initials: Y
authors.lastname: Kubo
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005145:Face; D005260:Female; D005385:Fingers; D017789:Granuloma, Pyogenic / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D019301:Oleic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D009829:Oleic Acids; D012597:Sclerosing Solutions / Q000008:administration & dosage / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014059:Tongue; D016896:Treatment Outcome
chemical_list: D009829:Oleic Acids; D012597:Sclerosing Solutions; C431086:monoethanolamine oleate; D019301:Oleic Acid