Molecular properties in cell adhesion: a physical and engineering perspective.
The past several years have seen accelerating growth in research directed towards the understanding and control of cell adhesion processes, from a spectrum of disciplinary approaches including molecular cell biology, biochemistry, biophysics and bioengineering. Consequently, our understanding of the mechanisms involved in cell adhesion has increased substantially. Corresponding quantitative analysis and modeling of the key molecular properties governing their action in regulating dynamic cell attachment and detachment events is crucial for advancing conceptual insight along with technological applications.
Orsello
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CE
Dept of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Lauffenburger
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DA
Hammer
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DA
D002448:Cell Adhesion