Syndromes involving craniosynostosis and midface hypoplasia.
This article reviews a number of well-known syndromes involving craniofacial synostosis and associated midface deficiencies. Syndromes discussed include Apert's, Crouzon's, Saethre-Chotzen, and Carpenter's. Clinical characteristics and genetic defects are discussed. A general approach to surgical management is outlined.
Katzen
J T
JT
Institute of Reconstructive Plastic Surgery, Variety Center for Craniofacial Rehabilitation, New York University Medical Center, New York, New York, USA.
McCarthy
J G
JG
D000168:Acrocephalosyndactylia / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000628:therapy; D000293:Adolescent; D003398:Craniosynostoses / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015995:Prevalence; D019651:Plastic Surgery Procedures / Q000379:methods*