title: Design of remarkably simple, yet potent urea-based inhibitors of glutamate carboxypeptidase II (NAALADase).
authors.forename: A P
authors.initials: AP
authors.lastname: Kozikowski
authors.forename: F
authors.initials: F
authors.lastname: Nan
authors.forename: P
authors.initials: P
authors.lastname: Conti
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: E
authors.initials: E
authors.lastname: Ramadan
authors.forename: T
authors.initials: T
authors.lastname: Bzdega
authors.forename: B
authors.initials: B
authors.lastname: Wroblewska
authors.forename: J H
authors.initials: JH
authors.lastname: Neale
authors.forename: S
authors.initials: S
authors.lastname: Pshenichkin
authors.forename: J T
authors.initials: JT
authors.lastname: Wroblewski
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology; D002268:Carboxypeptidases / Q000037:antagonists & inhibitors*; D002478:Cells, Cultured; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018690:Excitatory Amino Acid Agonists; D043425:Glutamate Carboxypeptidase II; D016202:N-Methylaspartate; D009457:Neuroglia / Q000166:cytology / Q000187:drug effects; D018696:Neuroprotective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship; D014508:Urea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D004791:Enzyme Inhibitors; D018690:Excitatory Amino Acid Agonists; D018696:Neuroprotective Agents; D016202:N-Methylaspartate; D014508:Urea; D002268:Carboxypeptidases; D043425:Glutamate Carboxypeptidase II