[Acute hepatitis B virus after chemotherapy for a case with germinoma].
A 28-year old man with HCG-producing germinoma had undergone chemotherapy and radiotherapy. On admission for the fifth session of maintenance chemotherapy, he was found to be positive for hepatitis B (HB)s antigen, but negative for HBs antibody. HBs antigen had been negative during previous admissions. Since liver function was normal, the patient underwent chemotherapy. During myelosuppression after chemotherapy, liver dysfunction developed and acute HB was diagnosed. He fortunately showed seroconversion 2 months after onset. Serum immunological examinations are required for patients receiving chemotherapy.
Uesaka
T
T
Department of Neurosurgery, Graduate School of Medical Sciencos, Kyushyu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Inamura
T
T
Ikezaki
K
K
Nakamizo
A
A
Yoshimoto
K
K
Inoha
S
S
Fukui
M
M
D000208:Acute Disease; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D002551:Cerebral Ventricle Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000532:radiotherapy; D003131:Combined Modality Therapy; D005047:Etoposide / Q000008:administration & dosage; D018237:Germinoma / Q000188:drug therapy* / Q000276:immunology / Q000532:radiotherapy; D006509:Hepatitis B / Q000209:etiology*; D006511:Hepatitis B Antigens / Q000097:blood; D006801:Humans; D008297:Male
D006511:Hepatitis B Antigens; D005047:Etoposide; D016190:Carboplatin