[Enhancement of efficacy of neoadjuvant polychemotherapy in combined treatment of lung cancer].
It is not infrequently that the known preoperative chemotherapy options come to be not very effective in the treatment of patients with pulmonary cancer by reason of a fraction of chemoresistant tumour cells. To enhance effectiveness of treatment we attempted preoperative thermochemotherapy. As many as 62 patients with pulmonary cancer were exposed preoperatively to a 40-minute r. f. hyperthermia plus chemotherapy. All these underwent radical surgery. The above method of neoadjuvant treatment permitted increasing significantly the 3-year survival of those patients presenting with locally spread pulmonary cancer.
Smolanka
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D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D008872:Microwaves / Q000627:therapeutic use; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin