title: Mode of perturbation of Asahi fibrin assembly by the extra oligosaccharides.
abstract: Steric hindrance by the backbone of extra oligosaccharides at gamma-Asn 308 may cause the repulsive force to widen the junction at the D:D interface, and thus, interfere with the longitudinal elongation and lateral association of protofibrils.
authors.affiliation: Division of Cell and Molecular Medicine, Center for Molecular Medicine, Jichi Medical School, Yakushiji 3311-1, Tochigi, 329-0498, Japan. sugosan@jichi.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Sugo
authors.forename: O
authors.initials: O
authors.lastname: Sekine
authors.forename: C
authors.initials: C
authors.lastname: Nakamikawa
authors.forename: H
authors.initials: H
authors.lastname: Endo
authors.forename: C L
authors.initials: CL
authors.lastname: Arocha-Piñango
authors.forename: M
authors.initials: M
authors.lastname: Matsuda
mesh_terms: D005337:Fibrin / Q000737:chemistry* / Q000648:ultrastructure; D015241:Fibrinogens, Abnormal / Q000737:chemistry*; D006801:Humans; D008855:Microscopy, Electron, Scanning; D009844:Oligosaccharides / Q000737:chemistry*
chemical_list: D015241:Fibrinogens, Abnormal; D009844:Oligosaccharides; D005337:Fibrin