title: Comparative study of vitrectomy for dropped nucleus with and without the use of perfluorocarbon liquid. Clinical, electrophysiological and visual field outcomes.
abstract: OBJECTIVE
  To compare pars plana vitrectomy for dropped nucleus with and without perfluorocarbon liquid.
  
  
  METHODS
  24 eyes with dropped nucleus were randomized to undergo PPV with perfluorodecalin, (study, n=12) and without it (control, n=12). Visual acuity, IOP, visual evoked response and electroretinography were noted at study entry and up to 3 months after PPV. Humphrey perimetry was done at 3 months.
  
  
  RESULTS
  Final visual acuity was >20/60 in 75% of study eyes and 41.6% of controls. The two groups were statistically comparable with regard to the above parameters before PPV and during follow-up. The timing of vitrectomy did not significantly influence the final visual acuity. A higher rate of complications was seen in the control group.
  
  
  CONCLUSIONS
  Perfluorodecalin facilitated the procedure and possibly minimized complications, and was found to be safe for intraoperative use in terms of recovery of visual acuity, stable ERG and VER, and normal visual fields.
authors.affiliation: Dr. Rajendra Prasad Centre For Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. allitverma@yahoo.com
authors.forename: L
authors.initials: L
authors.lastname: Verma
authors.forename: M
authors.initials: M
authors.lastname: Gogoi
authors.forename: H K
authors.initials: HK
authors.lastname: Tewari
authors.forename: A
authors.initials: A
authors.lastname: Kumar
authors.forename: D
authors.initials: D
authors.lastname: Talwar
mesh_terms: D000328:Adult; D000368:Aged; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D005466:Fluorocarbons / Q000627:therapeutic use*; D006801:Humans; D007907:Lens Nucleus, Crystalline / Q000473:pathology / Q000601:surgery*; D007906:Lens Subluxation / Q000209:etiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000502:physiology; D018918:Phacoemulsification / Q000009:adverse effects; D012160:Retina / Q000502:physiology; D016896:Treatment Outcome; D014792:Visual Acuity; D014794:Visual Fields / Q000502:physiology*; D014821:Vitrectomy
chemical_list: D005466:Fluorocarbons; C008805:perfluorodecalin