title: A study of intensified dietary support in underweight candidates for lung transplantation.
abstract: BACKGROUND
  No data is available on dietary intervention in candidates for lung transplantation and on the effect of different strategies for dietary support in this cohort.
  
  
  OBJECTIVE
  We therefore wanted to evaluate the effects of intensified nutritional support compared with simple support on energy intake and nutritional status.
  
  
  METHODS
  Our participants were underweight (n = 42) and normal-weight (control group, n = 29) candidates for lung transplantation. The underweight patients were randomized into two groups. Group A received intensified dietary counselling, ready-made liquid nutritional supplements free of charge and regular follow-ups, while group B received only one session of individual dietary counselling, no supplements and no follow-ups.
  
  
  RESULTS
  The mean intervention time was 21 weeks. Groups A and B both increased their energy intake and gained weight. Group A increased their energy intake from a median of 8.7 to 10.1 MJ (p < 0.01 compared with the control group after intervention) and gained a mean of 2.9 kg body weight (95% CI 1.2; 4.7, p = 0.005 compared with the control group), while group B increased from 7.4 to 10.8 MJ (p = 0.005) and gained 2.3 kg (1.2; 3.3, p = 0.002). Only group B increased their fat-free mass. In this group, an increase in O(2) saturation and a decrease in PaCO(2) were suggested. None of the groups improved its physical performance.
  
  
  CONCLUSIONS
  In candidates for lung transplantation we were unable to confirm the hypothesis that intensified nutritional support compared with a simple support increased compliance. Both groups achieved the goal for energy intake and gained weight.
authors.affiliation: Department of Thoracic Medicine, Rikshospitalet, Oslo, Norway.
authors.forename: L
authors.initials: L
authors.lastname: Førli
authors.lastname: Bjørtuft Ø
authors.forename: M
authors.initials: M
authors.lastname: Vatn
authors.forename: J
authors.initials: J
authors.lastname: Kofstad
authors.forename: J
authors.initials: J
authors.lastname: Boe
mesh_terms: D000328:Adult; D001835:Body Weight; D015331:Cohort Studies; D003376:Counseling; D002149:Energy Intake; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008173:Lung Diseases, Obstructive / Q000150:complications / Q000628:therapy*; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D009748:Nutrition Disorders / Q000150:complications / Q000628:therapy*; D009752:Nutritional Status; D018529:Nutritional Support; D011446:Prospective Studies; D012129:Respiratory Function Tests; D015430:Weight Gain