title: Acute corneal decompensation after silicone oil removal.
abstract: OBJECTIVE
  To assess acute corneal decompensation after silicone oil removal in some aphakic eyes with clear corneas whose anterior chambers were completely filled with silicone oil for a considerable period of time.
  
  
  METHODS
  Eight eyes of 8 patients who underwent vitrectomy and intraocular silicone oil injection were studied. All the eyes were aphakic and anterior chambers were completely filled with silicone oil. In all eyes, corneas were clear and no corneal finding indicating keratopathy was detected by slit-lamp microscopy before silicone oil removal. The mean silicone oil removal time was 4 months (range 2-7 months). A specular microscope was used for the evaluation of corneal endothelial changes and corneal pachometry was performed to observe corneal changes before and after the silicone oil removal in 5 eyes besides slit-lamp microscopy. The follow up period after silicone oil removal was 2-12 months (mean 6 months).
  
  
  RESULTS
  In all eyes severe corneal stromal edema and clouding was detected in the first day following silicone oil removal. Increased corneal thickness was seen in all eyes. Decreased (at or below critical levels) corneal cell density was detected by specular microscopy before and after silicone oil removal. No significant improvement was observed during the follow up period.
  
  
  CONCLUSIONS
  Eyes whose anterior chambers completely filled with silicone oil could be evaluated as clear corneas by slit lamp microscopy despite severe endothelial damage. We recommend that eyes with silicone oil in the anterior chambers should be monitored by a combination of slit-lamp microscopic examination and specular microscopy to determine the relative corneal endothelial tolerance to the silicone oil and endothelial damage. Early removal of the silicone oil can be considered when the retinal adhesion allows.
authors.affiliation: Gazi University, Medical Faculty, Department of Ophthalmology, Ankara, Turkey.
authors.forename: G
authors.initials: G
authors.lastname: Gurelik
authors.forename: N
authors.initials: N
authors.lastname: Safak
authors.forename: M
authors.initials: M
authors.lastname: Koksal
authors.forename: K
authors.initials: K
authors.lastname: Bilgihan
authors.forename: B
authors.initials: B
authors.lastname: Hasanreisoglu
mesh_terms: D000208:Acute Disease; D000328:Adult; D000867:Anterior Chamber / Q000187:drug effects / Q000473:pathology; D001036:Aphakia, Postcataract / Q000150:complications; D002452:Cell Count; D015715:Corneal Edema / Q000139:chemically induced* / Q000473:pathology; D003318:Corneal Opacity / Q000139:chemically induced* / Q000473:pathology; D003319:Corneal Stroma / Q000187:drug effects; D004728:Endothelium, Corneal / Q000187:drug effects / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000601:surgery; D012827:Silicone Oils / Q000009:adverse effects*; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils