title: Isochromosome (17)(q10) as the sole structural chromosomal rearrangement in a case of botryoid rhabdomyosarcoma.
abstract: We describe a case of botryoid rhabdomyosarcoma with the karyotype 53,XX,+2,+5,+8,+12,+13, i(17)(q10),+19,+20. Only two cytogenetically analyzed cases of this tumor were previously reported and structural chromosomal abnormalities in each tumor were different.
authors.affiliation: Department of Pathology, Scott & White Clinic and Memorial Hospital, Texas A&M University Health Science Center, Temple, TX 76508, USA.
authors.forename: K
authors.initials: K
authors.lastname: Clawson
authors.forename: L R
authors.initials: LR
authors.lastname: Donner
authors.forename: S M
authors.initials: SM
authors.lastname: Dobin
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002869:Chromosome Aberrations / Q000235:genetics* / Q000473:pathology; D025063:Chromosome Disorders; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics*; D020732:Cytogenetic Analysis; D005260:Female; D006801:Humans; D018404:Isochromosomes / Q000235:genetics*; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D014625:Vaginal Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology