title: Constraint-induced therapy of chronic aphasia after stroke.
abstract: Patients with chronic aphasia were assigned randomly to a group to receive either conventional aphasia therapy or constraint-induced (CI) aphasia therapy, a new therapeutic technique requiring intense practice over a relatively short period of consecutive days. CI aphasia therapy is realized in a communicative therapeutic environment constraining patients to practice systematically speech acts with which they have difficulty. Patients in both groups received the same amount of treatment (30 to 35 hours) as 10 days of massed-practice language exercises for the CI aphasia therapy group (3 hours per day minimum; 10 patients) or over a longer period of approximately 4 weeks for the conventional therapy group (7 patients). CI aphasia therapy led to significant and pronounced improvements on several standard clinical tests, on self-ratings, and on blinded-observer ratings of the patients' communicative effectiveness in everyday life. Patients who received the control intervention failed to achieve comparable improvements. Data suggest that the language skills of patients with chronic aphasia can be improved in a short period by use of an appropriate massed-practice technique that focuses on the patients' communicative needs.
authors.affiliation: MRC Cognition and Brain Sciences Unit, Cambridge, UK.
authors.forename: F
authors.initials: F
authors.lastname: Pulvermüller
authors.forename: B
authors.initials: B
authors.lastname: Neininger
authors.forename: T
authors.initials: T
authors.lastname: Elbert
authors.forename: B
authors.initials: B
authors.lastname: Mohr
authors.forename: B
authors.initials: B
authors.lastname: Rockstroh
authors.forename: P
authors.initials: P
authors.lastname: Koebbel
authors.forename: E
authors.initials: E
authors.lastname: Taub
mesh_terms: D000328:Adult; D000368:Aged; D001037:Aphasia / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013070:Speech Therapy; D020521:Stroke / Q000150:complications*; D016896:Treatment Outcome