title: Primary pulmonary rhabdomyosarcoma: report of a case in an adult and review of the literature.
abstract: A case of primary pulmonary rhabdomyosarcoma occurring in a 62-year-old man is reported, and a review of the literature is presented. The tumor affected the left upper lobe and involved the mediastinal lymph nodes. Immunohistochemical and ultrastructural studies supported the myogenic phenotype of the neoplasm. A left pneumonectomy was performed with complete surgical removal of the tumor. Postoperative radiotherapy was carried out. The patient is currently alive and free of disease 9 months after operation. Despite the rarity of primary pulmonary rhabdomyosarcoma, this tumor should be differentiated from other poorly differentiated pulmonary neoplasms and from metastatic sarcomas.
authors.affiliation: Dipartimento di Patologia Umana ed Oncologia, Università degli Studi di Firenze, Italia.
authors.forename: C E
authors.initials: CE
authors.lastname: Comin
authors.forename: M
authors.initials: M
authors.lastname: Santucci
authors.forename: L
authors.initials: L
authors.lastname: Novelli
authors.forename: S
authors.initials: S
authors.lastname: Dini
mesh_terms: D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012208:Rhabdomyosarcoma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure