title: Evaluation of the addiction history of a dead woman after exhumation and sectional hair testing.
abstract: In Greece, sectional hair analysis, in addition to clinical examination, has been used as a valuable tool for the confirmation of a person's history of drug use. The present report concerns the toxicologic analysis of the exhumed remains and hair samples of an 18-year-old woman. Postmortem toxicologic analysis of blood and urine confirmed recent opiate and cannabis use and indicated that death was associated with heroin abuse. Several months later, the woman's family asked for exhumation and reexamination of the body, insisting that the cause of death was homicide. The investigating judge ordered exhumation and new medicolegal examination of the body. The investigation of the drug profile along the hair shaft was undertaken by analyzing hair sections 1 cm from the hair root for morphine, 6-monoacetylmorphine, heroin, and cannabinoids. The total lengths of the hair samples ranged from 8 to 11 cm. The total morphine levels in the hair sections corresponding to the 3-month period before death were significantly lower (1.5-2.85 ng/mg) than those of the 4- to 10-month period before death (7.4-14.8 ng/mg). An interpretation of these results may be occasional drug use (with considerable attenuation of use during the last 3 months before death). Decrease of tolerance to heroin caused by abstinence and relapse in use could have been the cause of death.
authors.affiliation: Department of Forensic Sciences, University of Crete, Greece.
authors.forename: A M
authors.initials: AM
authors.lastname: Tsatsakis
authors.forename: M N
authors.initials: MN
authors.lastname: Tzatzarakis
authors.forename: D
authors.initials: D
authors.lastname: Psaroulis
authors.forename: C
authors.initials: C
authors.lastname: Levkidis
authors.forename: M
authors.initials: M
authors.lastname: Michalodimitrakis
mesh_terms: D000293:Adolescent; D017809:Fatal Outcome; D005260:Female; D018732:Forensic Anthropology; D008401:Gas Chromatography-Mass Spectrometry; D006197:Hair / Q000737:chemistry*; D006556:Heroin Dependence / Q000473:pathology*; D006801:Humans; D009020:Morphine / Q000032:analysis*; D009294:Narcotics / Q000032:analysis*
chemical_list: D009294:Narcotics; D009020:Morphine