A new cytotoxic naphthopyrone dimer from Paepalanthus bromelioides.
A new naphthopyrone dimer was isolated from the capitula of Paepalanthus bromelioides by chromatographic procedures. It structure was deduced from spectrometric data. On colorimetric assay for cytotoxicity the new dimer showed IC50 of 55.9 microM.
Coelho
R G
RG
Instituto de Química de Araraquara, Departmento de Quimica Organica, CP 355, CEP 14801-970 Araraquara-SP, Brazil.
Vilegas
W
W
Devienne
K F
KF
Raddi
M S
MS
D002478:Cells, Cultured / Q000187:drug effects; D006801:Humans; D019684:Magnoliopsida; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification*
D009281:Naphthalenes; D010936:Plant Extracts; D011753:Pyrones; C432445:naphthopyrone dimer