ZitB (YbgR), a member of the cation diffusion facilitator family, is an additional zinc transporter in Escherichia coli.
The Escherichia coli zitB gene encodes a Zn(II) transporter belonging to the cation diffusion facilitator family. ZitB is specifically induced by zinc. ZitB expression on a plasmid rendered zntA-disrupted E. coli cells more resistant to zinc, and the cells exhibited reduced accumulation of (65)Zn, suggesting ZitB-mediated efflux of zinc.
Grass
G
G
Department of Soil, Water, and Environmental Science, University of Arizona, Tucson, AZ 85721, USA.
Fan
B
B
Rosen
B P
BP
Franke
S
S
Nies
D H
DH
Rensing
C
C
D001426:Bacterial Proteins / Q000235:genetics / Q000502:physiology*; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology*; D002412:Cations; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D006706:Homeostasis; D008670:Metals / Q000494:pharmacology; D015032:Zinc / Q000378:metabolism*
D001426:Bacterial Proteins; D002352:Carrier Proteins; D002412:Cations; D008670:Metals; C017800:zinc-binding protein; D015032:Zinc