title: [Synthesis of 1-hydroxyalkyl-3-substituted ureas and thioureas as a substrates for alcohol dehydrogenase].
abstract: A series of 1-(2-hydroxyethyl)- and 1-(3-hydroxyethyl)-3-substituted ureas and thioureas were synthesized. 1-(3-Hydroxyethyl)-3-acylthioureas were shown to be specific substrates for alcohol dehydrogenase in vitro.
authors.affiliation: Institute of Biological Medicine, ul. Akademika Oparina 4, Mascow, 117815 Russia.
authors.forename: O N
authors.initials: ON
authors.lastname: Leonov
authors.forename: V M
authors.initials: VM
authors.lastname: Shcherbakov
authors.forename: V M
authors.initials: VM
authors.lastname: Devichenskiĭ
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Kriukova
authors.forename: E A
authors.initials: EA
authors.lastname: Vorontsov
authors.forename: S L
authors.initials: SL
authors.lastname: Kuznetsov
authors.forename: L N
authors.initials: LN
authors.lastname: Kriukov
mesh_terms: D000426:Alcohol Dehydrogenase / Q000737:chemistry*; D013379:Substrate Specificity; D013890:Thiourea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry*; D014508:Urea / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D014508:Urea; D000426:Alcohol Dehydrogenase; D013890:Thiourea