Transcranial magnetic stimulation studies in the Miller Fisher syndrome: evidence of corticospinal tract abnormality.
OBJECTIVE
To evaluate serial central motor conduction time in the Miller Fisher syndrome.


METHODS
Three patients with classic Miller Fisher syndrome were evaluated clinically. They had serial central motor conduction times measured with transcranial magnetic stimulation and nerve conduction studies. Motor evoked potentials were recorded from the first dorsal interossei and abductor hallucis muscles.


RESULTS
All three patients showed reduction in central motor conduction times in tandem with gradual clinical improvement at each review.


CONCLUSIONS
There is electrophysiological evidence of a central reversible corticospinal tract conduction abnormality in the Miller Fisher syndrome.
Lo
Y L
YL
Department of Neurology, Singapore General Hospital, Outram Road, 169608, Singapore. gnrlyl@sgh.gov.sg
Ratnagopal
P
P
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019846:Miller Fisher Syndrome / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology; D011712:Pyramidal Tracts / Q000002:abnormalities* / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology; D050781:Transcranial Magnetic Stimulation