title: Folate and chemoprevention of colorectal cancer: Is 5-methyl-tetrahydrofolate an active antiproliferative agent in folate-treated colon-cancer cells?
authors.affiliation: Second Department of Medicine and Gastroenterology, Johann Wolfgang Goethe University, Frankfurt, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Akoglu
authors.forename: D
authors.initials: D
authors.lastname: Faust
authors.forename: V
authors.initials: V
authors.lastname: Milovic
authors.forename: J
authors.initials: J
authors.lastname: Stein
mesh_terms: D018938:Caco-2 Cells; D002453:Cell Cycle / Q000187:drug effects*; D015179:Colorectal Neoplasms / Q000188:drug therapy / Q000517:prevention & control*; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000378:metabolism* / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D013763:Tetrahydrofolates / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D013763:Tetrahydrofolates; C010920:dihydrofolate; C030371:5,6,7,8-tetrahydrofolic acid; D005492:Folic Acid; C005984:5-methyltetrahydrofolate