title: Clinical study of guided bone regeneration and/or bone grafts in the treatment of ligature-induced peri-implantitis defects in dogs.
abstract: This study evaluated, by clinical analysis, the hard tissue response following treatment of ligature-induced peri-implantitis defects in 5 dogs. The mandibular premolars were removed from both sides of the jaw. After 3 months of healing, two titanium implants were placed on each side of the mandible. Following abutment connection, 3 months later, experimental peri-implantitis was induced by the placement of cotton ligatures in a submarginal position. Ligatures and abutments were removed after one month and the bony defects were randomly assigned to one of the following treatments: debridement (DE), debridement plus guided bone regeneration (GBR), debridement plus mineralized bone graft (BG) and debridement plus guided bone regeneration associated with mineralized bone graft (GBR + BG). The peri-implant bone defects were clinically measured before and 5 months post-treatment. Results showed a higher percentage of vertical bone fill for GBR + BG (27.77 +/- 14.07) followed by GBR (21.78 +/- 16.19), BG (21.26 +/- 6.87), DE (14.03 +/- 5.6). However, there were no statistically significant differences between any of the treatments proposed (one way repeated measures analysis of variance, P = 0.265).
authors.affiliation: Department of Prosthodontics and Periodontics, Division of Periodontics, School of Dentistry at Piracicaba, UNICAMP, Piracicaba, SP, Brazil. nociti@fop.unicamp.br
authors.forename: F H
authors.initials: FH
authors.lastname: Nociti Júnior
authors.forename: R G
authors.initials: RG
authors.lastname: Caffesse
authors.forename: E A
authors.initials: EA
authors.lastname: Sallum
authors.forename: M A
authors.initials: MA
authors.lastname: Machado
authors.forename: C M
authors.initials: CM
authors.lastname: Stefani
authors.forename: A W
authors.initials: AW
authors.lastname: Sallum
mesh_terms: D016301:Alveolar Bone Loss / Q000601:surgery; D000704:Analysis of Variance; D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D016025:Bone Transplantation; D003094:Collagen; D003758:Dental Implantation, Endosseous / Q000009:adverse effects; D015921:Dental Implants / Q000009:adverse effects*; D004285:Dogs; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D020007:Implants, Experimental / Q000009:adverse effects; D008026:Ligation; D008567:Membranes, Artificial; D010518:Periodontitis / Q000209:etiology / Q000601:surgery*; D013357:Subgingival Curettage
chemical_list: C106416:Bio-Gide; D001672:Biocompatible Materials; D015921:Dental Implants; D008567:Membranes, Artificial; D003094:Collagen