title: Successful treatment of cutaneous Langerhans cell histiocytosis with low-dose methotrexate.
abstract: Langerhans cell histiocytosis (LCH) can be a difficult therapeutic problem. We present a 40-year-old woman with a 4-year history of LCH who was successfully treated with low-dose methotrexate (20 mg weekly).
authors.affiliation: Department of Dermatology, Friedrich-Wilhelms University, Sigmund Freud Str. 25, D-53105 Bonn, Germany.
authors.forename: A E
authors.initials: AE
authors.lastname: Steen
authors.forename: K H
authors.initials: KH
authors.lastname: Steen
authors.forename: R
authors.initials: R
authors.lastname: Bauer
authors.forename: T
authors.initials: T
authors.lastname: Bieber
mesh_terms: D000328:Adult; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology
chemical_list: D003879:Dermatologic Agents; D008727:Methotrexate