title: [Functional neuroimaging in patients with rapid cycling bipolar depression].
abstract: Bipolar patients with a rapid cycling clinical course constitute an interesting sub-group for studies focused on the pathophysiology of the disorder, since several switches can be studied by the investigators in a short period of time. At present, functional neuroimaging techniques, as SPECT and PET, may be used for the neurobiological study of affective disorders. Few longitudinal functional neuroimaging studies assessing the different phases of bipolar disorder have been carried out. However, the published data suggest an asymmetrical temporal lobe dysfunction in depressive and manic phases of bipolar depression. Further studies with larger samples of patients are needed in order to improve our knowledge of the pathophysiology of bipolar disorder.
authors.affiliation: Institut Clínic de Psiquiatria i Psicologia, Hospital Clínic, Universitat de Barcelona, Stanley Foundation Barcelona Center.
authors.forename: A
authors.initials: A
authors.lastname: Benabarre
authors.forename: E
authors.initials: E
authors.lastname: Vieta
authors.forename: F
authors.initials: F
authors.lastname: Martín
authors.forename: F
authors.initials: F
authors.lastname: Lomeña
mesh_terms: D001714:Bipolar Disorder / Q000000981:diagnostic imaging* / Q000188:drug therapy; D001921:Brain / Q000000981:diagnostic imaging*; D005260:Female; D005544:Forecasting; D005625:Frontal Lobe / Q000000981:diagnostic imaging; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000000981:diagnostic imaging; D008032:Limbic System / Q000000981:diagnostic imaging; D008137:Longitudinal Studies; D008875:Middle Aged; D010507:Periodicity; D010865:Pilot Projects; D017397:Prefrontal Cortex / Q000000981:diagnostic imaging; D011619:Psychotropic Drugs / Q000627:therapeutic use; D013702:Temporal Lobe / Q000000981:diagnostic imaging; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D011619:Psychotropic Drugs