title: Effect of moderate alcohol consumption on fibrinogen levels in healthy volunteers is discordant with effects on C-reactive protein.
abstract: In a diet-controlled, crossover trial with 10 middle-aged men and 9 postmenopausal women, baseline concentrations of fibrinogen influenced the magnitude of decrease of fibrinogen after moderate alcohol consumption. The mechanism of reduction is specific for fibrinogen and unrelated to a reduction in C-reactive protein.
authors.affiliation: TNO Nutrition and Food Research, Department of Nutritional Physiology, P.O. Box 360, 3700 AJ Zeist, The Netherlands. sierksma@voeding.tno.nl
authors.forename: A
authors.initials: A
authors.lastname: Sierksma
authors.forename: M S
authors.initials: MS
authors.lastname: van der Gaag
authors.forename: C
authors.initials: C
authors.lastname: Kluft
authors.forename: H F
authors.initials: HF
authors.lastname: Hendriks
mesh_terms: D000428:Alcohol Drinking / Q000097:blood*; D002097:C-Reactive Protein / Q000378:metabolism*; D018592:Cross-Over Studies; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D012016:Reference Values
chemical_list: D005340:Fibrinogen; D002097:C-Reactive Protein