Recurrent portopulmonary hypertension after liver transplantation: management with epoprostenol and resolution after retransplantation.
We report a case of portopulmonary hypertension in which the pulmonary hypertension resolved after initial orthotopic liver transplantation. Portopulmonary hypertension recurred when the transplanted liver failed and again resolved after a second liver transplantation. Intravenous epoprostenol was administered perioperatively to control the pulmonary hypertension in both instances.
Kett
D H
DH
Divisions of Pulmonary and Critical Care Medicine, Department of Medicine, University of Miami School of Medicine, Miami, FL, USA. dkett@med.miami.edu
Acosta
R C
RC
Campos
M A
MA
Rodriguez
M J
MJ
Quartin
A A
AA
Schein
R M
RM
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D011464:Epoprostenol / Q000627:therapeutic use*; D006439:Hemodynamics; D006801:Humans; D006975:Hypertension, Portal / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012086:Reoperation; D017211:Treatment Failure
D000959:Antihypertensive Agents; D011464:Epoprostenol