title: Guillain-Barré syndrome in a child with acute lymphoblastic leukemia.
abstract: A 4-year-old boy with acute lymphoblastic leukemia receiving maintenance treatment developed quadriparesis, facial palsy, difficulty in swallowing, and hypertension following a respiratory infection and candida septicemia. Examination of the cerebrospinal fluid was normal initially but later showed albuminocytologic dissociation, the characteristic finding of Guillain-Barré syndrome. Complete recovery occurred after treatment with intravenous immunoglobulin. Differential diagnosis of Guillain-Barré syndrome from vincristine toxicity in patients with leukemia and possible association with the infections are discussed.
authors.affiliation: Gazi University Medical Faculty, Department of Pediatric Hematology, Ankara, Turkey. yuziar_12@yahoo.com
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Aral
authors.forename: T
authors.initials: T
authors.lastname: Gursel
authors.forename: G
authors.initials: G
authors.lastname: Ozturk
authors.forename: A
authors.initials: A
authors.lastname: Serdaroglu
mesh_terms: D002675:Child, Preschool; D020275:Guillain-Barre Syndrome / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D014750:Vincristine / Q000009:adverse effects
chemical_list: D014750:Vincristine