Automated fluorescence analysis of CAG repeats at the human androgen receptor gene (HUMARA): evaluation of polymorphism in an Italian sample and report of a new allele.
The HUMARA CAG repeats polymorphism was studied in an Italian population sample. Polymerase chain reaction amplification and automated fluorescent analysis were used. A total of 19 and 15 repeats was observed in female and male subjects, respectively, and one new allele was found. The authors conclude that this X-linked short tandem repeat, typed without ambiguity and with a heterozygosity of 0.902, is useful in parentage testing of female subjects.
Pelotti
S
S
Department of Medicine and Public Health, University of Bologna, Italy.
Maiolini
E
E
Bini
C
C
Rimondi
S
S
Luiselli
D
D
Pappalardo
G
G
D004247:DNA / Q000032:analysis*; D016172:DNA Fingerprinting / Q000379:methods; D017931:DNA Primers; D005828:Genetics, Population; D006801:Humans; D007558:Italy; D010290:Parents; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011944:Receptors, Androgen / Q000235:genetics*; D018911:Trinucleotide Repeats / Q000235:genetics; D044465:White People / Q000235:genetics*
C410798:AR protein, human; D017931:DNA Primers; D011944:Receptors, Androgen; D004247:DNA