Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells.
Mesenchymal stem cells were isolated and a subpopulation of cells--multipotent adult progenitor cells--were identified that have the potential for multilineage differentiation. Their ability to engraft and differentiate in vivo is under investigation.
Reyes
M
M
Stem Cell Institute and Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Verfaillie
C M
CM
D000367:Age Factors; D000818:Animals; D000077214:Becaplermin; D001854:Bone Marrow Cells / Q000166:cytology; D016026:Bone Marrow Transplantation; D002454:Cell Differentiation; D019070:Cell Lineage; D002469:Cell Separation; D002478:Cells, Cultured / Q000187:drug effects; D004815:Epidermal Growth Factor / Q000494:pharmacology; D006801:Humans; D008648:Mesoderm / Q000166:cytology*; D051379:Mice; D010641:Phenotype; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology; D020574:Proto-Oncogene Proteins c-sis; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology* / Q000187:drug effects; D016615:Telomere / Q000648:ultrastructure
D010982:Platelet-Derived Growth Factor; D020574:Proto-Oncogene Proteins c-sis; D000077214:Becaplermin; D004815:Epidermal Growth Factor