title: Influences of directed research and clinical observations on the development of a tartar control whitening dentifrice.
abstract: Early literature described the benefits of cleaning the mouth and teeth to prevent tartar accumulation and tooth loss. For more than a century, the need for meticulous tooth scaling and regular brushing to maintain oral health has been recorded. More recently, because of innovative research into the chemical and biological activity of saliva, dentifrices have been formulated which specifically interrupt the mineralization of plaque and food debris to stain and calculus. Proof of efficacy of these dentifrices are obtained with well-designed clinical tests which quantify stain and calculus by using reliable scoring systems.
authors.affiliation: Colgate-Palmolive Technology Center, Piscataway, NJ, USA.
authors.forename: A R
authors.initials: AR
authors.lastname: Volpe
authors.forename: J H
authors.initials: JH
authors.lastname: Manhold
authors.forename: R R
authors.initials: RR
authors.lastname: Lobene
authors.forename: S L
authors.initials: SL
authors.lastname: Yankell
mesh_terms: D002986:Clinical Trials as Topic; D045424:Complex Mixtures; D003728:Dental Calculus / Q000517:prevention & control*; D018865:Dental Research; D003802:Dentifrices / Q000627:therapeutic use*; D006801:Humans; D011122:Polyphosphates; D012824:Silicic Acid; D012822:Silicon Dioxide; D012969:Sodium Fluoride; D014075:Tooth Discoloration / Q000517:prevention & control*; D014100:Toothpastes
chemical_list: D045424:Complex Mixtures; D003802:Dentifrices; D011122:Polyphosphates; D014100:Toothpastes; C546060:hydrated silica gel-based toothpaste; D012824:Silicic Acid; D012822:Silicon Dioxide; D012969:Sodium Fluoride