The nontreatment of childhood ITP (or "the art of medicine consists of amusing the patient until nature cures the disease").
The management of childhood acute idiopathic thrombocytopenic purpura is controversial, with recent guidelines highlighting the lack of suitable evidence upon which to base management decisions. Three European centers have used an expectant policy and results over the past decade demonstrate that this is safe and convenient for the majority of children. Adequate parental education about the condition from an experienced specialist is essential, together with open access for children should they develop any problems. A clinical stratification of such patients must be incorporated into any future trials, together with quality of life assessment to discover the impact of restrictions on lifestyle, particularly in adolescents with chronic ITP who may need a different approach.
Bolton-Maggs
P H
PH
Royal Liverpool Children's Hospital, Alder Hey, UK. p.h.boltonmaggs@liv.ac.uk
Dickerhoff
R
R
Vora
A J
AJ
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003657:Decision Making; D006801:Humans; D007223:Infant; D010290:Parents; D010976:Platelet Count; D017410:Practice Guidelines as Topic; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis / Q000628:therapy*; D028761:Withholding Treatment