Synthesis of differentially substituted hexaethynylbenzenes based on tandem Sonogashira and Negishi cross-coupling reactions.
[reaction: see text] Synthesis of polyethynyl-substituted aromatic compounds was achieved efficiently by the use of the Negishi cross-coupling reaction, and this method, coupled with the Sonogashira reaction, was applied to the synthesis of differentially substituted hexaethynylbenzenes from chloroiodobenzenes.
Sonoda
M
M
Department of Chemistry, Faculty of Engineering Science, Osaka University, and CREST, Japan Science and Technology Corporation (JST), Toyonaka, Osaka 560-8531, Japan.
Inaba
A
A
Itahashi
K
K
Tobe
Y
Y