title: Crystallization and preliminary crystallographic studies of an apoptosis-linked calcium-binding protein ALG-2.
abstract: ALG-2 is an apoptosis-linked Ca(2+)-binding protein. It is required for T-cell receptor-induced, Fas-induced and glucocorticoid-induced cell death. Structurally, ALG-2 contains five putative EF-hand Ca(2+)-binding sites. Ca(2+)-free ALG-2 was crystallized in two crystal forms by the hanging-drop vapour-diffusion method.
authors.affiliation: School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026, People's Republic of China.
authors.forename: F
authors.initials: F
authors.lastname: Wu
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.forename: W
authors.initials: W
authors.lastname: Gong
mesh_terms: D000818:Animals; D017209:Apoptosis; D051017:Apoptosis Regulatory Proteins; D002118:Calcium / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D006801:Humans; D020648:Peptide Elongation Factor 1 / Q000378:metabolism; D011487:Protein Conformation
chemical_list: D051017:Apoptosis Regulatory Proteins; D002135:Calcium-Binding Proteins; C097753:PDCD6 protein, human; D020648:Peptide Elongation Factor 1; D002118:Calcium