Optic neuropathy and central retinal artery occlusion in non-Hodgkin lymphoma.
We report a patient with systemic large cell non-Hodgkin lymphoma in remission who presented with the rare combination of optic neuropathy and central retinal artery occlusion. Another unusual feature of this case is the lack of enhancement in the affected region on magnetic resonance imaging only hours after the first dose of steroids. Despite prompt treatment with steroids and radiotherapy, lymphomatous infiltration of the meninges developed 2 months later and was ultimately fatal.
Fierz
A B
AB
Department of Ophthalmology, University Hospital, Zürich, Switzerland.
Sartoretti
S
S
Thoelen
A M
AM
D000368:Aged; D001766:Blindness / Q000175:diagnosis / Q000209:etiology; D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis; D005134:Eye Neoplasms / Q000150:complications* / Q000175:diagnosis; D017809:Fatal Outcome; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology*; D010211:Papilledema / Q000175:diagnosis / Q000209:etiology; D015356:Retinal Artery Occlusion / Q000175:diagnosis / Q000209:etiology*