A subtype-selective thyromimetic designed to bind a mutant thyroid hormone receptor implicated in resistance to thyroid hormone.
Ye
H F
HF
Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.
O'Reilly
K E
KE
Koh
J T
JT
D004351:Drug Resistance; D006801:Humans; D008956:Models, Chemical; D008958:Models, Molecular; D018716:Molecular Mimicry; D011988:Receptors, Thyroid Hormone / Q000378:metabolism*; D013974:Thyroxine / Q000378:metabolism*
D011988:Receptors, Thyroid Hormone; D013974:Thyroxine