title: [Functioning biological activity of mean mineralized sodium bicarbonate in water from the "Pitoniakówka" source in Szczawnica, designed for health resort potable cures].
abstract: In the experiments on animals the biological activity of the water from its intake "Pitoniakówka" (outflow B + C + D + G) in Szczawnica has been determined. The basic investigations were carried out on rats whom in the course of 24 days the investigated water was being administered to drink ad libitum or by probe in a single daily dose of 10.7 ml/kg of body weight. It has been ascertained that the water caused a statistically significant increase of the concentration of sodium and a fall of the levels of potassium, magnesium, calcium, total cholesterol, the HDL fraction of cholesterol, total lipids in the blood serum, also of hematocrit, hemoglobin and erythrocytes. The investigated water inhibited the motor activity of the small intestine of the rabbit, caused increased urination and increased water turnover in the organism. A long-lasting application of the investigated water may lead to the genesis of metabolic acidosis. There was not observed any cholagonic and any chologenic activity of the investigated water in guinea pigs or any effect of that water on the elements of the carbohydrate metabolism, the protein metabolism or on the peripheral blood smear in rats.
authors.affiliation: Zakład Tworzyw Uzdrowiskowych Państwowy Zakład Higieny 60-821 Poznań.
authors.forename: M
authors.initials: M
authors.lastname: Drobnik
authors.forename: T
authors.initials: T
authors.lastname: Latour
mesh_terms: D000138:Acidosis / Q000139:chemically induced; D000284:Administration, Oral; D000818:Animals; D001452:Balneology; D001834:Body Water / Q000378:metabolism*; D002118:Calcium / Q000097:blood; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D004573:Electrolytes / Q000097:blood*; D004784:Environmental Monitoring; D004906:Erythrocyte Count; D005769:Gastrointestinal Motility / Q000187:drug effects; D006168:Guinea Pigs; D006294:Health Resorts; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D008055:Lipids / Q000097:blood; D008274:Magnesium / Q000097:blood; D008900:Mineral Waters / Q000008:administration & dosage*; D011044:Poland; D011188:Potassium / Q000097:blood; D011817:Rabbits; D051381:Rats; D012964:Sodium / Q000097:blood*; D017693:Sodium Bicarbonate / Q000008:administration & dosage*
chemical_list: D008076:Cholesterol, HDL; D004573:Electrolytes; D006454:Hemoglobins; D008055:Lipids; D008900:Mineral Waters; D017693:Sodium Bicarbonate; D002784:Cholesterol; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium