title: Arthritis as a rare extra-intestinal manifestation of acute sigmoid diverticulitis.
abstract: BACKGROUND
  A causal association between acute diverticulitis of the sigmoid colon and arthritis has rarely been reported.
  
  
  METHODS
  We report the case of a 60-year-old patient who developed migrating arthritis of the knee and ankle during the recurring episode of acute diverticulitis of the sigmoid colon. Treatment with NSAIDs and antibiotics had little effect on joint disease, but medical treatment was successful in reducing the diverticulitis-related symptoms. Arthritis promptly improved after surgical resection of the sigmoid colon, and 30 months later the patient is free of symptoms in the previously affected joints.
  
  
  CONCLUSIONS
  Five cases of diverticulitis-associated arthritis have been reported. The similar case reported here reconfirms that joint disease has a limited response to medical approaches. Colon resection is recommended for patients with diverticulitis-associated arthritis which does not respond promptly to antibiotic therapy.
authors.affiliation: Cattedra di Chirurgia Generale, Università di Brescia, Italia.
authors.forename: S
authors.initials: S
authors.lastname: Alba
authors.forename: R
authors.initials: R
authors.lastname: Nascimbeni
authors.forename: E
authors.initials: E
authors.lastname: Di Betta
authors.forename: V
authors.initials: V
authors.lastname: Villanacci
authors.forename: B
authors.initials: B
authors.lastname: Salerni
mesh_terms: D000208:Acute Disease; D003248:Constipation / Q000209:etiology; D003937:Diagnosis, Differential; D004239:Diverticulitis, Colonic / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D012213:Rheumatic Fever / Q000188:drug therapy / Q000209:etiology*; D012810:Sigmoid Diseases / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery