SC-1, an antimycotic spirostan saponin from Solanum chrysotrichum.
A new antimycotic steroidal saponin named SC-1 has been isolated from the leaves of Solanum chrysotrichum by bioassay-guided fractionation. The structure of SC-1 was characterized as 3-O-[beta-quinovopyranosyl(1-->6)-beta-glucopyranosyl(1-->6)-beta- glucopyranosyl]chlorogenin on the basis of spectral analyses and chemical evidence.
Alvarez
L
L
Pérez
M C
MC
González
J L
JL
Navarro
V
V
Villarreal
M L
ML
Olson
J O
JO
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid; D008279:Magnetic Resonance Imaging; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D019657:Solanaceae / Q000737:chemistry*; D013150:Spirostans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D014249:Trichophyton / Q000187:drug effects
C431507:3-O-(quinovopyranosyl(1-6)glucopyranosyl(1-6)glucopyranosyl)chlorogenin; D000935:Antifungal Agents; D010936:Plant Extracts; D012503:Saponins; D013150:Spirostans