[Effect of noradrenaline on the amplitude and temporal parameters of multiquantal currents and on the kinetics of evoked quantal secretion of a transmitter].
Noradrenaline caused a significant increase of the multiquantal endplate currents (EPC) amplitude, the EPC rising phase/the rising phase of miniature EPC ratio diminishing, at that. Noradrenaline seems to synchronise the process of quanta secretion in the EPC generation. Thus when a single stimulation of motor nerve results in release of several tenths of a transmitter, noradrenaline may increase the multiquantal EPC amplitude through synchronising of the transmitter release involved in the generation.
Bukharaeva
E A
EA
Kazan Institute of Biochemistry and Biophysics, Russian Acad. Sci., Russia, 420503, Kazan, Box 30.
Gaĭnulov
R Kh
RKh
Nikol'skiĭ
E E
EE
D000818:Animals; D004594:Electrophysiology; D066298:In Vitro Techniques; D008564:Membrane Potentials; D009045:Motor Endplate / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000378:metabolism*; D009638:Norepinephrine / Q000494:pharmacology / Q000502:physiology*; D011895:Rana ridibunda; D013995:Time
D018377:Neurotransmitter Agents; D009638:Norepinephrine