title: A prospective randomized trial of laparoscopic Nissen fundoplication with anterior vs posterior hiatal repair.
abstract: OBJECTIVE
  The technique used for repair of the esophageal hiatus during laparoscopic Nissen fundoplication can influence the likelihood of postoperative dysphagia.
  
  
  METHODS
  A prospective double-blind randomized control trial.
  
  
  METHODS
  A university teaching hospital.
  
  
  METHODS
  A total of 102 patients with proven gastroesophageal reflux disease, undergoing a laparoscopic Nissen fundoplication were randomized to undergo fundoplication with either anterior (47 patients) or posterior (55 patients) repair of the diaphragmatic hiatus. Patients were excluded for the following reasons: they had esophageal motility disorders, required a concurrent abdominal procedure, had undergone previous antireflux surgery, or had very large hiatus hernias.
  
  
  METHODS
  Laparoscopic Nissen fundoplication with anterior vs posterior hiatal repair.
  
  
  METHODS
  Independent assessment of dysphagia, heartburn, patient satisfaction, and other symptoms 1, 3, and 6 months following surgery, using multiple standardized clinical grading systems. Objective measurement of lower esophageal sphincter pressure, esophageal emptying time, distal esophageal acid exposure, and endoscopic assessment of postoperative anatomy and esophageal mucosa.
  
  
  RESULTS
  Symptoms of postoperative dysphagia, relief of heartburn, and overall satisfaction 6 months after surgery were not influenced by the hiatal repair technique. However, to achieve a similar incidence of dysphagia, more patients who initially underwent posterior hiatal repair required a second surgical procedure (6 vs 0 patients). The hiatal repair technique did not affect the likelihood of early postoperative paraesophageal herniation.
  
  
  CONCLUSIONS
  Anterior suturing of the hiatus appears to be at least as good in the short-term as posterior suturing as a method of narrowing the hiatus during laparoscopic Nissen fundoplication.
authors.affiliation: University of Adelaide, Department of Surgery, Royal Adelaide Hospital, South Australia 5000, Australia. david.watson@adelaide.edu.au
authors.forename: D I
authors.initials: DI
authors.lastname: Watson
authors.forename: G G
authors.initials: GG
authors.lastname: Jamieson
authors.forename: P G
authors.initials: PG
authors.lastname: Devitt
authors.forename: J A
authors.initials: JA
authors.lastname: Kennedy
authors.forename: T
authors.initials: T
authors.lastname: Ellis
authors.forename: R
authors.initials: R
authors.lastname: Ackroyd
authors.forename: T
authors.initials: T
authors.lastname: Lafullarde
authors.forename: P A
authors.initials: PA
authors.lastname: Game
mesh_terms: D000328:Adult; D000368:Aged; D003680:Deglutition Disorders / Q000209:etiology / Q000517:prevention & control*; D004311:Double-Blind Method; D005260:Female; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D006356:Heartburn / Q000209:etiology / Q000517:prevention & control*; D006551:Hernia, Hiatal / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008365:Manometry; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome