[Primary brain lymphomas].
In the Department of Neurosurgery of the Medical University of Warsaw 11 patients with primary central nervous system lymphomas were diagnosed and treated between 1990 and 1999. The patients comprised of 6 females and 5 males, aged 23 to 86 years, with most patients presenting in the sixth decade. The time from first symptoms to the diagnosis ranged from a few days to 5 months. In the majority of patients, the leading symptoms were: headaches, motor weakness, aphasia and memory disturbance. Initial diagnosis was based on MR in 3 patients, CT in 7 and on both CT and MR in 1 patient. The frontal lobe was the most common site of involvement. All the patients underwent surgery. The histological diagnosis was confirmed by immunohistochemical analysis using monoclonal antibodies: CD 20, CD3, CKMNF 116. In all cases, a B-cell type lymphoma was diagnosed. Radiotherapy was administered to 4 patients, 2 received chemotherapy and 1 received combined treatment. The median survival time so far is 17.6 months.
Bojanowski
K
K
Kliniki Neurochirurgii AM w Warszawie.
Kroh
H
H
Marchel
A
A
Sulejman
W
W
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D005260:Female; D005625:Frontal Lobe / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate; D014057:Tomography, X-Ray Computed