title: Synthesis and structure-activity relationships of benzophenone hydrazone derivatives with insecticidal activity.
abstract: A broad range of benzophenone hydrazone derivatives was prepared and tested against selected chewing insect pests, allowing the analysis of structure-activity relationships. Good activity was found only when the aromatic rings were substituted at the 4-positions with an halogen atom and a triflate or perhaloalkoxy group. In contrast, a number of substituents on the hydrazone part led to active compounds, the best results being achieved with acyl-type substituents. The excellent laboratory and greenhouse activity of the best representatives was confirmed in semi-field trials against Spodoptera littoralis.
authors.affiliation: Novartis Crop Protection AG, 4002 Basel, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Böger
authors.forename: D
authors.initials: D
authors.lastname: Dürr
authors.forename: L
authors.initials: L
authors.lastname: Gsell
authors.forename: R G
authors.initials: RG
authors.lastname: Hall
authors.forename: F
authors.initials: F
authors.lastname: Karrer
authors.forename: O
authors.initials: O
authors.lastname: Kristiansen
authors.forename: P
authors.initials: P
authors.lastname: Maienfisch
authors.forename: A
authors.initials: A
authors.lastname: Pascual
authors.forename: A
authors.initials: A
authors.lastname: Rindlisbacher
mesh_terms: D000818:Animals; D001577:Benzophenones / Q000138:chemical synthesis* / Q000494:pharmacology; D001681:Biological Assay; D006835:Hydrazones / Q000138:chemical synthesis* / Q000494:pharmacology; D007306:Insecticides / Q000138:chemical synthesis* / Q000494:pharmacology; D007915:Lepidoptera; D015394:Molecular Structure; D013329:Structure-Activity Relationship
chemical_list: D001577:Benzophenones; D006835:Hydrazones; D007306:Insecticides