title: Dural ectasia and conventional radiography in the Marfan lumbosacral spine.
abstract: OBJECTIVE
  To determine how well conventional radiographic findings can predict the presence of dural ectasia in Marfan patients.
  
  
  METHODS
  Twelve Marfan patients without dural ectasia and 21 Marfan patients with dural ectasia were included in the study. Five radiographic measurements were made of the lumbosacral spine: interpediculate distance, scalloping value, sagittal canal diameter, vertebral body width, and transverse process width.
  
  
  RESULTS
  The following measurements were significantly larger in patients with dural ectasia: interpediculate distances at L3-L4 levels (P<0.03); scalloping values at the L1 and L5 levels (P<0.05); sagittal diameters of the vertebral canal at L5-S1 (P<0.03); transverse process to width ratios at L2 (P<0.03). Criteria were developed for diagnosis of dural ectasia in Marfan patients. These included presence of one of the following: interpediculate distance at L4 > or = 38.0 mm, sagittal diameter at S1 > or = 18.0 mm, or scalloping value at L5 > or = 5.5 mm.
  
  
  CONCLUSIONS
  Dural ectasia in Marfan syndrome is commonly associated with several osseous changes that are observable on conventional radiographs of the lumbosacral spine. Conventional radiography can detect dural ectasia in patients with Marfan syndrome with a very high specificity (91.7%) but a low sensitivity (57.1%).
authors.affiliation: Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, USA.
authors.forename: N U
authors.initials: NU
authors.lastname: Ahn
authors.forename: L
authors.initials: L
authors.lastname: Nallamshetty
authors.forename: U M
authors.initials: UM
authors.lastname: Ahn
authors.forename: J M
authors.initials: JM
authors.lastname: Buchowski
authors.forename: P S
authors.initials: PS
authors.lastname: Rose
authors.forename: E S
authors.initials: ES
authors.lastname: Garrett
authors.forename: K M
authors.initials: KM
authors.lastname: Kebaish
authors.forename: P D
authors.initials: PD
authors.lastname: Sponseller
mesh_terms: D000328:Adult; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging; D004388:Dura Mater / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D008382:Marfan Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D011859:Radiography; D012447:Sacrum