title: An unusual cutaneous metastasis from hepatocellular carcinoma.
abstract: Cutaneous metastases from hepatocellular carcinoma are rare. In this report we detail a case of hepatocellular carcinoma with the unusual manifestations of multiple skin metastases. A 49-year-old male, who had received surgical resection of hepatocellular carcinoma one year prior, presented with multiple reddish-blue, firm, painless and nonulcerative cutaneous papules and nodules over the fingers, palms, toes, soles and back. Pathology of the cutaneous nodules showed characteristic hepatocellular carcinoma with trabecular gland formation. These lesions grew very rapidly and developed to cauliflower appearances which had not been described previously in the literature. The patient died of respiratory failure secondary to lung metastasis two months after the first appearance of the skin lesions.
authors.affiliation: Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, 201, Sec. 2, Shih-Pai Road, Taipei 112, Taiwan.
authors.forename: Y R
authors.initials: YR
authors.lastname: Fang
authors.forename: Y S
authors.initials: YS
authors.lastname: Huang
authors.forename: J C
authors.initials: JC
authors.lastname: Wu
authors.forename: Y
authors.initials: Y
authors.lastname: Chao
authors.forename: S H
authors.initials: SH
authors.lastname: Tsay
authors.forename: C Y
authors.initials: CY
authors.lastname: Chan
authors.forename: F Y
authors.initials: FY
authors.lastname: Chang
authors.forename: S D
authors.initials: SD
authors.lastname: Lee
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000556:secondary*