[The role of nitric oxide in carcinogenesis and progression of neoplastic processes].
The aim of the review is to outline the current knowledge about the role of nitric oxide in the processes of proliferation and apoptosis in tumor. Special emphasis has been placed on its direct cytotoxic influence on a cell where as a highly active free radical it may compromise different cellular functions. Nitric oxide literature, regarding its role in the pathogenesis of some gynecological and breast cancer has been briefly reviewed.
Laudański
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P
Zakładu Endokrynologii Ginekologicznej AM w Białymstoku.
Anchim
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T
Wołczyński
S
S
D000818:Animals; D017209:Apoptosis; D001943:Breast Neoplasms / Q000378:metabolism; D018450:Disease Progression; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism*; D010051:Ovarian Neoplasms / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D002583:Uterine Cervical Neoplasms / Q000378:metabolism
D005609:Free Radicals; D009569:Nitric Oxide; D013482:Superoxide Dismutase