title: A case of hemorrhagic gallbladder paraganglioma causing acute cholecystitis.
abstract: Gallbladder paraganglioma is a very rare tumor and so far only a few cases have been reported. Most of these were asymptomatic and were found incidentally during operation. Recently, we experienced a gallbladder paraganglioma that gave rise to hemorrhage, which in turn caused acute cholecystitis. Our case involved a 45 year-old female patient complaining of an intermittent right upper abdominal pain. After a preoperative evaluation, cholecystectomy and lymphadenectomy were performed under the impression of gallbladder cancer with acute cholecystitis. Postoperative pathologic examination revealed a hemorrhagic gallbladder paraganglioma accompanied by acute cholecystitis. Immunohistochemical staining of the chief cells for neuron specific enolase, chromogranin and synaptophysin were positive. Sustentacular cells also stained positively for S100 protein.
authors.affiliation: Department of Surgery, Inha University College of Medicine, Incheon, Korea.
authors.forename: Y U
authors.initials: YU
authors.lastname: Cho
authors.forename: J Y
authors.initials: JY
authors.lastname: Kim
authors.forename: S K
authors.initials: SK
authors.lastname: Choi
authors.forename: Y S
authors.initials: YS
authors.lastname: Hur
authors.forename: K Y
authors.initials: KY
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Kim
authors.forename: S I
authors.initials: SI
authors.lastname: Ahn
authors.forename: K C
authors.initials: KC
authors.lastname: Hong
authors.forename: Z H
authors.initials: ZH
authors.lastname: Woo
authors.forename: J Y
authors.initials: JY
authors.lastname: Han
authors.forename: S H
authors.initials: SH
authors.lastname: Shin
mesh_terms: D000208:Acute Disease; D002764:Cholecystitis / Q000209:etiology*; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications* / Q000473:pathology; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010235:Paraganglioma / Q000150:complications* / Q000473:pathology