Calcium signalling: store-operated channel found at last.
The intestinal Ca(2+) transport protein CaT1 has recently been shown to have the biophysical characteristics of the Ca(2+)-release activated Ca(2+) channel that refills internal Ca(2+) stores following agonist-elicited release. This finding highlights a hitherto unrecognized link between epithelial Ca(2+) transport and Ca(2+) signalling.
Petersen
O H
OH
MRC Secretory Control Research Group, The Physiological Laboratory, University of Liverpool, Crown Street, L69 3BX, Liverpool, UK. o.h.petersen@liv.ac.uk
Fedirko
N V
NV
D000818:Animals; D002118:Calcium / Q000378:metabolism; D015220:Calcium Channels / Q000502:physiology*; D020013:Calcium Signaling; D004847:Epithelial Cells / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism; D017136:Ion Transport; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D050916:TRPV Cation Channels
D015220:Calcium Channels; D050916:TRPV Cation Channels; C120776:TRPV6 channel; D002118:Calcium