[A case of cardiac myxoma with multiple brain hemorrhage].
A case of cardiac myxoma with multiple brain hemorrhage is reported. A 57-year-old male had complained of lower abdominal pain, diarrhea and fever for 3 days. On admission, he was in a condition of disseminated intravascular coagulation and sepsis. An abdominal CT scan showed infarction in the right kidney and spleen and an echocardiogram also showed myxoma in the left atrium. Although he presented no neurological symptoms, the brain CT showed multiple brain hemorrhage in the bilateral brain hemispheres. Total resection of the tumor was carried out for the improvement of the patient's general condition. Vimentin, S-100 protein and neuron specific enolase was positive in immunological staining and the pathological diagnosis was myxoma. Postoperative recovery of consciousness was poor and left hemiparesis developed. CT showed the increase of hematoma but angiography showed no cerebral aneurysm. The symptoms improved with conservative therapy. However the enhanced lesion remained in the right parietal lobe and an operation was performed 5 months later. The myxoma cell could not be found in the pathological examination, so tumor embolism, cerebral infarction, hemorrhagic infarction due to DIC, hematoma enlargement caused by heparinization during operation were suspected to have occurred in this order without tumor growth.
Oyama
H
H
Department of Neurosurgery, Chukyo Hospital, 1-1-10 Sanjo, Minami-ku, Nagoya 457-8510, Japan.
Nakayama
M
M
Ikeda
A
A
Maeda
M
M
Miyahara
T
T
Inoue
S
S
Sakurai
H
H
Murayama
H
H
Hasegawa
H
H
Iizuka
H
H
Endoh
O
O
Shibuya
M
M
D001921:Brain / Q000000981:diagnostic imaging; D006338:Heart Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology*; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D009232:Myxoma / Q000150:complications / Q000473:pathology*; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011859:Radiography; D018805:Sepsis / Q000209:etiology; D013203:Staphylococcal Infections / Q000209:etiology; D013211:Staphylococcus aureus