title: Anaesthetic management of a child with a positive family history of malignant hyperthermia for posterior fossa surgery in the sitting position.
abstract: A 6-year-old boy with a positive family history of malignant hyperthermia presented for posterior fossa craniectomy and excision of medulloblastoma. A nontriggering anaesthetic was therefore planned using infusions of propofol and remifentanil and a vapour free anaesthetic system delivering an oxygen/air mixture. The surgery was carried out with the child in the sitting position.
authors.affiliation: Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Wootton
authors.forename: J
authors.initials: J
authors.lastname: Lockie
mesh_terms: D000758:Anesthesia / Q000379:methods*; D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous; D002528:Cerebellar Neoplasms / Q000601:surgery; D002648:Child; D003388:Cranial Fossa, Posterior / Q000601:surgery*; D003399:Craniotomy; D020022:Genetic Predisposition to Disease; D006801:Humans; D015192:Infratentorial Neoplasms / Q000601:surgery; D008297:Male; D008305:Malignant Hyperthermia / Q000235:genetics* / Q000517:prevention & control; D008527:Medulloblastoma / Q000601:surgery; D010880:Piperidines; D011187:Posture; D015742:Propofol; D000077208:Remifentanil
chemical_list: D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil; D015742:Propofol