Circadian programming in cyanobacteria.
Prokaryotic cyanobacteria express robust circadian (daily) rhythms under the control of a timing mechanism that is independent of the cell division cycle. This biological clock orchestrates global regulation of gene expression. Competition experiments demonstrate that fitness is enhanced when the circadian period is consonant with the period of the environmental cycle. Mutational analyses have identified three clock genes in the organism, one of which is related to DNA recombinases and helicases. We propose a new model for the core 'clockwork' that implicates rhythmic changes in the status of the chromosome that underly the rhythms of gene expression.
Mori
T
T
Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
Johnson
C H
CH
D001683:Biological Clocks / Q000235:genetics* / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D002940:Circadian Rhythm; D000458:Cyanobacteria / Q000235:genetics / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial; D008163:Luminescent Measurements; D008954:Models, Biological; D017440:Photoperiod