Dynamin family of mechanoenzymes.
The dynamin family of proteins is continually growing, and in recent years members have been localized to areas of mitochondrial fission, plant phragmoplasts and chloroplasts, and viral ribonucleoprotein complexes. All the dynamin-like proteins examined to-date appear to assemble into oligomers, such as rings or spirals; however, it remains to be determined if a global mechanism of action exists. Even the role of dynamin in vesicle formation remains controversial as to whether it behaves as a molecular switch or as a mechanochemical enzyme.
Danino
D
D
Laboratory of Cell Biochemistry and Biology, Building 8, Room 419, MSC 0851, 8 Center Drive, National Institute of Health, Bethesda, Maryland 20892, USA. dganitd@intra.niddk.nih.gov
Hinshaw
J E
JE
D000818:Animals; D034281:Dynamins; D020558:GTP Phosphohydrolases / Q000737:chemistry / Q000502:physiology*; D007371:Interferon-gamma / Q000502:physiology; D008928:Mitochondria / Q000648:ultrastructure; D008954:Models, Biological; D010940:Plant Proteins / Q000502:physiology; D017434:Protein Structure, Tertiary; D022161:Transport Vesicles / Q000201:enzymology
D010940:Plant Proteins; D007371:Interferon-gamma; D020558:GTP Phosphohydrolases; D034281:Dynamins