title: High-dose-rate endobronchial brachytherapy in endobronchial metastatic malignant chondroid syringoma.
abstract: A 65-year-old man with malignant chondroid syringoma (MCS) was found to have pulmonary metastases in the form of multiple pulmonary nodules 4 years after wide excision and adjuvant radiotherapy of a primary abdominal wall tumor. Atelectasis of the lingula due to obstructive endobronchial metastasis, resistant to combination chemotherapy, led us to perform high-dose rate (HDR) endobronchial brachytherapy for the first time in this rare tumor with a favorable response. This case emphasizes the role of HDR brachytherapy as a palliative procedure in endobronchial tumors not responding to other treatment modalities, even those considered to be radioresistant.
authors.affiliation: Division of Pulmonary Medicine, Department of Oncology, Rambam Medical Center, 31096 Haifa, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Solomonov
authors.forename: E
authors.initials: E
authors.lastname: Rosenblatt
authors.forename: O
authors.initials: O
authors.lastname: Ben-Izhak
authors.forename: L
authors.initials: L
authors.lastname: Goralnik
authors.forename: M
authors.initials: M
authors.lastname: Yigla
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000532:radiotherapy*; D000368:Aged; D001918:Brachytherapy / Q000379:methods; D001980:Bronchi / Q000473:pathology; D001984:Bronchial Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000556:secondary*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D010166:Palliative Care; D012468:Salivary Gland Neoplasms / Q000473:pathology*