title: [Pathogenesis of chronic hepatitis C].
abstract: Recent investigations revealed a specific interaction of virus with the host immune system. HCV is able to escape and modify the host's immune response, notably the rate of production and specificity of rheumatoid factor--the basis for mixed cryoglobulins and various non-organospecific and some organ-specific autoantibodies. Further studies are required to decode the mechanisms of virus-host immune system interaction for substantiating the treatment and prevention of HCV infection.
authors.forename: T M
authors.initials: TM
authors.lastname: Ignatova
authors.forename: V V
authors.initials: VV
authors.lastname: Serov
mesh_terms: D016174:Hepacivirus; D019698:Hepatitis C, Chronic / Q000209:etiology* / Q000276:immunology / Q000821:virology; D006801:Humans