title: Neuropsychological and psychiatric complications in endoscopic third ventriculostomy: a clinical case report.
abstract: The clinical case report of a patient who underwent an endoscopic third ventriculostomy for the treatment of a slit ventricle syndrome is presented. After surgery the patient developed a severe complication consisting of an organic personality disorder, characterised by impulsiveness, physical heteroaggressiveness, binge eating, hypersomnia and impairment of memory, and frontal-executive functions.A frontal lobe lesion may explain some of the symptoms presented, such as the uncontrolled impulses, the aggressive behaviour, and even the binge eating. However, a longitudinal neuropsychological evaluation showed a severe deficit in immediate memory and difficulties in planning and consolidation of newly learned information, which may be best related to damage in the frontal basal structures of the brain: the fornix and its connection to the hippocampus and the mamillary bodies. Postoperative MR images confirmed the clinical hypothesis. The emergence of such a severe organic personality disorder and cognitive disturbances as a psychiatric complication of an endoscopic third ventriculostomy has not, it seems, been previously reported elsewhere. Clinicians should take these possible complications into account when recommending this so-called minimally invasive neuroendoscopic procedure.
authors.affiliation: Institut Clínic de Psiquiatria I Psicologia, Hospital Clínic de Barcelona, Facultat de Medicina de la Universitat de Barcelona, C/ Villarroel 170, 08036 Barcelona, Spain. 31555abh@comb.es
authors.forename: A
authors.initials: A
authors.lastname: Benabarre
authors.forename: J
authors.initials: J
authors.lastname: Ibáñez
authors.forename: T
authors.initials: T
authors.lastname: Boget
authors.forename: J
authors.initials: J
authors.lastname: Obiols
authors.forename: A
authors.initials: A
authors.lastname: Martínez-Aran
authors.forename: E
authors.initials: E
authors.lastname: Vieta
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000473:pathology / Q000523:psychology* / Q000601:surgery*; D004724:Endoscopy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D010554:Personality Disorders / Q000209:etiology* / Q000523:psychology; D013577:Syndrome; D020542:Third Ventricle / Q000473:pathology / Q000601:surgery*