Nuclear magnetic resonance-based approaches for lead generation in drug discovery.
Peng
J W
JW
Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts 02139, USA.
Lepre
C A
CA
Fejzo
J
J
Abdul-Manan
N
N
Moore
J M
JM
D001665:Binding Sites; D015195:Drug Design; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005461:Fluorine; D008024:Ligands; D046911:Macromolecular Substances; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry; D011522:Protons
D008024:Ligands; D046911:Macromolecular Substances; D011506:Proteins; D011522:Protons; D005461:Fluorine