title: Sudan: the possible original focus of visceral leishmaniasis.
abstract: Fifty-two Leishmania strains, obtained from human patients and dogs in a visceral leishmaniasis focus in Sudan, were characterized by isoenzyme electrophoresis (15 enzymes). The phylogenetic analysis showed that the 7 Leishmania zymodemes obtained hold ancestral positions on the phylogenetic tree, supporting the hypothesis of an East African origin of visceral leishmaniasis.
authors.affiliation: Laboratoire de Parasitologie et Centre National de Reference des Leishmanioses, CHU de Montpellier, France.
authors.forename: F
authors.initials: F
authors.lastname: Pratlong
authors.forename: J
authors.initials: J
authors.lastname: Dereure
authors.forename: B
authors.initials: B
authors.lastname: Bucheton
authors.forename: S
authors.initials: S
authors.lastname: El-Saf
authors.forename: A
authors.initials: A
authors.lastname: Dessein
authors.forename: G
authors.initials: G
authors.lastname: Lanotte
authors.forename: J P
authors.initials: JP
authors.lastname: Dedet
mesh_terms: D000818:Animals; D004285:Dogs; D004592:Electrophoresis, Starch Gel; D006801:Humans; D007527:Isoenzymes / Q000235:genetics; D007891:Leishmania / Q000145:classification* / Q000201:enzymology* / Q000235:genetics; D007898:Leishmaniasis, Visceral / Q000453:epidemiology* / Q000469:parasitology; D010802:Phylogeny; D013397:Sudan / Q000453:epidemiology
chemical_list: D007527:Isoenzymes