[Ciprofloxacin-induced vasculitis with cutaneous and renal involvement].
Quinolone antibiotics are frequently used in the practice of medicine. Nephrotoxic side effects related to the use of quinolones are uncommon. We report a patient in treatment with ciprofloxacin who presented with purpuric skin lesions and alteration of renal function. We review these antibacterial agents with special attention on associated adverse reactions, and present-day experience with the newer quinolone antibiotics.
Pons
R
R
Servicio de Nefrología, Hospital General Universitario de Valencia, Avda. Tres Cruces, s/n. 46014 Valencia.
Escutia
B
B
D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000139:chemically induced / Q000628:therapy; D000890:Anti-Infective Agents / Q000009:adverse effects*; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D001803:Blood Transfusion; D002939:Ciprofloxacin / Q000009:adverse effects*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006333:Heart Failure / Q000150:complications; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000150:complications; D011695:IgA Vasculitis / Q000139:chemically induced; D007674:Kidney Diseases / Q000139:chemically induced*; D011693:Purpura / Q000139:chemically induced*; D013924:Thrombophlebitis / Q000150:complications / Q000188:drug therapy; D014657:Vasculitis / Q000139:chemically induced*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced
D000890:Anti-Infective Agents; D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D002939:Ciprofloxacin