[Characteristics of humoral immunity to rubella virus in residents of Moscow in 1998-1999].
A total of 400 blood samples were collected from residents of Moscow in 1998-1999, 369 from adults aged mainly 19-31 years and from children aged 5-12 years. The mean incidence of antirubella antibody was 76.5%; the value varied in different age groups. The highest percentage of antibody detection was observed in men aged 19-25 years (91.8%) and the lowest in pregnant women aged 18-38 years (66-67%). Estimation of antihemagglutinin titers in international Units showed that antibody titer 1:40 and higher protected from infection; such titers were detected in 73.6% examinees. In pregnant women the level of immunological defense was very low (only 56%), which necessitates urgent vaccination of adolescent girls and young women. The results of EIA were compatible with the results of indirect hemagglutination test (IHAT), but EIA was much more sensitive in cases with low titers of IHAT.
Gaĭdamovich
S Ia
SIa
Tkachenko
A V
AV
Larichev
V F
VF
Alekseev
S B
SB
Butenko
A M
AM
Filatov
F P
FP
Naumenko
M G
MG
Rusanova
A V
AV
Krasil'nikov
I V
IV
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D000917:Antibody Formation; D005260:Female; D006801:Humans; D008297:Male; D009031:Moscow / Q000453:epidemiology; D011247:Pregnancy; D012409:Rubella / Q000097:blood / Q000453:epidemiology / Q000276:immunology*; D012412:Rubella virus / Q000276:immunology*
D000914:Antibodies, Viral