title: gamma-Glutamyl transpeptidase as a possible marker of Sertoli cells in fish testes for studies of xenoestrogens.
abstract: Estrogenic chemicals are known to have marked effects on the reproductive system of male fish. Finding useful markers of reproductive effects are therefore of great importance and interest. gamma-Glutamyl transpeptidase (gamma-GTP) is a possible marker of Sertoli cells in testes of fish. In the present study we have examined the relationship between the activity of gamma-GTP and the histological structure of the Sertoli cells in testes of five fish species (guppy, Poecilia reticulata; platyfish, Xiphophorus maculatus; eelpout, Zoarces viviparus; rainbow trout, Oncorhynchus mykiss; flounder, Platichthys flesus). In general we found that the more distinct the Sertoli cells the higher the activity of gamma-GTP.
authors.affiliation: Institute of Biology, University of Southern Denmark, Odense University, Campusvej 55, DK-5230 Odense, Denmark. tinac@biology.ou.dk
authors.forename: T
authors.initials: T
authors.lastname: Christiansen
authors.forename: K
authors.initials: K
authors.lastname: Kinnberg
authors.forename: P
authors.initials: P
authors.lastname: Bjerregaard
authors.forename: B
authors.initials: B
authors.lastname: Korsgaard
mesh_terms: D000818:Animals; D015415:Biomarkers; D003532:Cyprinodontiformes; D004967:Estrogens / Q000633:toxicity*; D005399:Fishes / Q000378:metabolism*; D005432:Flounder; D008297:Male; D017686:Oncorhynchus mykiss; D010473:Perciformes; D011036:Poecilia; D012708:Sertoli Cells / Q000201:enzymology* / Q000648:ultrastructure; D013737:Testis / Q000201:enzymology; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D004967:Estrogens; D005723:gamma-Glutamyltransferase