title: [Malaria--chemoprophylaxis 2001].
abstract: An estimated 20,000 to 30,000 cases of imported malaria are annually diagnosed in industrialised countries. Some 700 of them concern Swiss travellers and foreign guests. Exposure prophylaxis and chemoprophylaxis for high risk destinations lower the risk of malarial disease. The latter is defined as regular intake of antimalarial drugs in subtherapeutic dosage in order to suppress the development of clinical disease. Drugs are usually taken from one week before travel until four weeks after return from an endemic area. Mefloquine, doxycycline, chloroquine plus proguanil, and presumably soon also atovaquone plus proguanil are available in Switzerland for chemoprophylaxis.
authors.affiliation: Departementsleiter Medizin & Diagnostik, Schweizerisches Tropeninstitut, Postfach, CH-4002 Basel. hatz@keep.touch.ch
authors.forename: F R
authors.initials: FR
authors.lastname: Hatz
authors.forename: B
authors.initials: B
authors.lastname: Beck
authors.forename: J
authors.initials: J
authors.lastname: Blum
authors.forename: M
authors.initials: M
authors.lastname: Funk
authors.forename: H
authors.initials: H
authors.lastname: Furrer
authors.forename: B
authors.initials: B
authors.lastname: Genton
authors.forename: B
authors.initials: B
authors.lastname: Holzer
authors.forename: L
authors.initials: L
authors.lastname: Loutan
authors.forename: K
authors.initials: K
authors.lastname: Markwalder
authors.forename: P A
authors.initials: PA
authors.lastname: Raeber
authors.forename: P
authors.initials: P
authors.lastname: Schlagenhauf
authors.forename: G
authors.initials: G
authors.lastname: Siegl
authors.forename: R
authors.initials: R
authors.lastname: Steffen
authors.forename: D
authors.initials: D
authors.lastname: Stürchler
authors.forename: R
authors.initials: R
authors.lastname: Wyss
mesh_terms: D000349:Africa / Q000453:epidemiology; D000962:Antimalarials / Q000627:therapeutic use*; D001208:Asia / Q000453:epidemiology; D053626:Atovaquone; D002738:Chloroquine / Q000627:therapeutic use; D000075202:Contraindications; D004318:Doxycycline / Q000627:therapeutic use; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D006801:Humans; D008288:Malaria / Q000453:epidemiology / Q000517:prevention & control*; D016778:Malaria, Falciparum / Q000517:prevention & control; D015767:Mefloquine / Q000627:therapeutic use; D009285:Naphthoquinones / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D002727:Proguanil / Q000627:therapeutic use; D013020:South America / Q000453:epidemiology; D013557:Switzerland; D014195:Travel
chemical_list: D000962:Antimalarials; D004338:Drug Combinations; D009285:Naphthoquinones; D002738:Chloroquine; D004318:Doxycycline; D002727:Proguanil; D015767:Mefloquine; D053626:Atovaquone