title: Ulcerative colitis and colonic lymphoma: a theoretical link.
abstract: Ulcerative colitis (UC) is an inflammatory disease of the colon and rectum. Although colonic adenocarcinoma is a recognized complication of UC there have been few reported cases of gastrointestinal lymphoma arising in this setting. We describe our experience with such a case and review the literature that attempts to explain possible genetic etiologies for the malignant transformation of gastrointestinal lymphoid tissue to lymphoma as well as a link between UC and lymphoma.
authors.affiliation: Division of Colon and Rectal Surgery, Henry Ford Hospital, Detroit, Michigan 48202, USA.
authors.forename: S
authors.initials: S
authors.lastname: Khan
authors.forename: G K
authors.initials: GK
authors.lastname: Anderson
authors.forename: A C
authors.initials: AC
authors.lastname: Eppstein
authors.forename: J C
authors.initials: JC
authors.lastname: Eggenberger
authors.forename: D A
authors.initials: DA
authors.lastname: Margolin
mesh_terms: D003093:Colitis, Ulcerative / Q000150:complications*; D003110:Colonic Neoplasms / Q000209:etiology*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors