The stereospecificity of secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus is partially determined by active site water.
Heiss
C
C
Department of Chemistry, and Center for Metalloenzyme Studies University of Georgia, Athens, Georgia 30602-2556, USA.
Laivenieks
M
M
Zeikus
J G
JG
Phillips
R S
RS
D000429:Alcohol Oxidoreductases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D001421:Bacteria, Anaerobic / Q000201:enzymology*; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D020134:Catalytic Domain; D006094:Gram-Positive Bacteria / Q000201:enzymology; D007700:Kinetics; D017354:Point Mutation; D013237:Stereoisomerism; D013379:Substrate Specificity; D013816:Thermodynamics; D014867:Water / Q000737:chemistry
D001426:Bacterial Proteins; D014867:Water; D000429:Alcohol Oxidoreductases; C025192:isopropanol dehydrogenase (NADP)