Functional magnetic stimulation facilitates colonic transit in rats.
OBJECTIVE
To investigate the effect of functional magnetic stimulation (FMS) on colonic transit in rats.


METHODS
Experimental.


METHODS
Functional magnetic stimulation laboratory in a Veterans Administration health care system.


METHODS
Twenty-four female Wistar rats, divided into an experimental group and a control group.


METHODS
All rats had technetium 99m (Tc 99m) infused through a cecal catheter to assess colonic transit times. FMS was performed over the cervical region; a figure of 8 magnetic coil was used in the experimental group. The colon was removed and sectioned into 10 segments, and a stool sample was taken in both groups.


METHODS
Distribution of radioactivity within the large intestine and stool were measured.


RESULTS
Geometric center calculations showed significant differences (p <.001) between the control group and the experimental group when the distribution of radioactivity along the colon was measured. The percentage of Tc 99m recovered from the stool in the experimental group was significantly higher than the percentage recovered from the control group.


CONCLUSIONS
FMS facilitates colonic transit in a rat model.
Lin
V W
VW
Functional Magnetic Stimulation Laboratory, Spinal Cord Injury/Disorder Health Care Group, VA Long Beach Health Care System, Long Beach, CA 90822-5201, USA.
Hsiao
I
I
Goodwin
D
D
Perkash
I
I
D000818:Animals; D003106:Colon / Q000000981:diagnostic imaging* / Q000502:physiology; D005260:Female; D005769:Gastrointestinal Motility; D008280:Magnetics; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D051381:Rats; D017208:Rats, Wistar; D017556:Technetium Compounds
D019275:Radiopharmaceuticals; D017556:Technetium Compounds