Effect of moderate alcohol consumption on fibrinogen levels in healthy volunteers is discordant with effects on C-reactive protein.
In a diet-controlled, crossover trial with 10 middle-aged men and 9 postmenopausal women, baseline concentrations of fibrinogen influenced the magnitude of decrease of fibrinogen after moderate alcohol consumption. The mechanism of reduction is specific for fibrinogen and unrelated to a reduction in C-reactive protein.
Sierksma
A
A
TNO Nutrition and Food Research, Department of Nutritional Physiology, P.O. Box 360, 3700 AJ Zeist, The Netherlands. sierksma@voeding.tno.nl
van der Gaag
M S
MS
Kluft
C
C
Hendriks
H F
HF
D000428:Alcohol Drinking / Q000097:blood*; D002097:C-Reactive Protein / Q000378:metabolism*; D018592:Cross-Over Studies; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D012016:Reference Values
D005340:Fibrinogen; D002097:C-Reactive Protein