title: In vitro activities of MK-0826 and 16 other antimicrobials against Bacteroides fragilis group strains.
abstract: The activity of MK-0826, a new carbapenem, against 309 Bacteroides fragilis group strains was investigated and compared with that of 11 other beta-lactam and 5 non-beta-lactam agents. MK-0826 showed excellent activity (MICs ranged from < or =0.06 to 4 microg/ml). The new carbapenem may be useful in the treatment of mixed anaerobic infections involving B. fragilis group strains.
authors.affiliation: Department of Clinical Microbiology, Hospital Clínico San Carlos, 28040 Madrid, Spain. cbetriu@efd.net
authors.forename: C
authors.initials: C
authors.lastname: Betriu
authors.forename: A
authors.initials: A
authors.lastname: Sánchez
authors.forename: M L
authors.initials: ML
authors.lastname: Palau
authors.forename: M
authors.initials: M
authors.lastname: Gómez
authors.forename: J J
authors.initials: JJ
authors.lastname: Picazo
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001441:Bacteroides fragilis / Q000187:drug effects* / Q000302:isolation & purification; D015780:Carbapenems / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems; C108047:L 749345