Severe calcinosis cutis associated with treatment of hypoparathyroidism in a dog.
A 6-month-old, female border collie was referred for evaluation of hypocalcemia, hyperphosphatemia, fever, and painful ventral abdominal skin. She had recently been treated intravenously and subcutaneously (SC) with a diluted 10% calcium gluconate solution. The medical evaluation supported the diagnosis of primary hypoparathyroidism, but the subsequent hospital course was complicated by severe calcinosis cutis, which caused extensive skin necrosis and marked debilitation. This patient illustrates that administration of a calcium gluconate solution SC can be associated with extensive morbidity when administered to hyperphosphatemic patients.
Schaer
M
M
Department of of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610, USA.
Ginn
P E
PE
Fox
L E
LE
Leon
J
J
Ramirez
F M
FM
D000005:Abdomen; D000818:Animals; D002114:Calcinosis / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D002125:Calcium Gluconate / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D006996:Hypocalcemia / Q000097:blood / Q000188:drug therapy / Q000662:veterinary*; D007011:Hypoparathyroidism / Q000097:blood / Q000188:drug therapy / Q000662:veterinary*; D007279:Injections, Subcutaneous / Q000662:veterinary; D012871:Skin Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*
D002125:Calcium Gluconate