title: [Recombinant hirudin in neurosurgery].
abstract: We report the case of a 70-year-old woman with paraplegia resulting from spinal cord compression secondary to an epidural haematoma. Because of an arrhythmia, a mitral valve replacement and the high risk of venous thrombosis, an anticoagulant treatment was introduced postoperatively. The patient having previously developed an type II heparin-induced thrombocytopaenia, a treatment by lepirudine was established successfully.
authors.affiliation: Département d'anesthésie-réanimation 1, hôpital Roger-Salengro, CHRU Lille, 59037 Lille, France.
authors.forename: P
authors.initials: P
authors.lastname: Poidevin
authors.forename: V
authors.initials: V
authors.lastname: Salomé
authors.forename: B
authors.initials: B
authors.lastname: Riegel
authors.forename: M F
authors.initials: MF
authors.lastname: Verdin
authors.forename: A
authors.initials: A
authors.lastname: Bernard
authors.forename: R
authors.initials: R
authors.lastname: Krivosic-Horber
mesh_terms: D000368:Aged; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006407:Hematoma, Epidural, Cranial / Q000150:complications; D024764:Hirudin Therapy; D006801:Humans; D019635:Neurosurgical Procedures; D010264:Paraplegia / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control*; D011994:Recombinant Proteins / Q000627:therapeutic use; D013119:Spinal Cord Injuries / Q000601:surgery
chemical_list: D005343:Fibrinolytic Agents; D011994:Recombinant Proteins