title: Immune response of greenback flounder Rhombosolea tapirina after exposure to contaminated marine sediment and diet.
abstract: Non-specific immune response of greenback flounder, Rhombosolea tapirina, exposed to contaminated marine sediments was examined. Reference sediments from Port Sorell and contaminated sediments from Deceitful Cove, Tasmania, Australia were investigated. Hatchery-reared flounder were exposed to reference sediment, contaminated sediment or contaminated sediment and diet for 6 weeks. Phagocytic capacity and lysozyme response in flounder were examined on cessation of exposure trial. Significant differences were found in phagocytic capacity and lysozyme response between treatments. Exposure to contaminated sediment, irrespective of diet or benthic disturbance elicited inhibition of phagocytic efficiency in flounder. Disturbance of contaminated sediment stimulated lysozyme activity. The immune response in flounder indicates potential immunotoxicity of sediment from Deceitful Cove.
authors.affiliation: School of Aquaculture, University of Tasmania, PO Box 1214, Launceston, Tasmania 7250, Australia.
authors.forename: J A
authors.initials: JA
authors.lastname: Mondon
authors.forename: S
authors.initials: S
authors.lastname: Duda
authors.forename: B F
authors.initials: BF
authors.lastname: Nowak
mesh_terms: D000818:Animals; D001315:Australia; D004032:Diet / Q000662:veterinary*; D005432:Flounder / Q000276:immunology*; D019015:Geologic Sediments; D008670:Metals / Q000032:analysis / Q000633:toxicity; D009113:Muramidase / Q000378:metabolism; D010587:Phagocytosis / Q000187:drug effects; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis / Q000633:toxicity; D012989:Soil Pollutants / Q000633:toxicity*
chemical_list: D008670:Metals; D011084:Polycyclic Aromatic Hydrocarbons; D012989:Soil Pollutants; D009113:Muramidase