New quinone-amino acid conjugates linked via a vinylic spacer.
Chloranil and 2,3-dichloro-1,4-naphthoquinone have been linked to different natural and unnatural amino acids via a vinylic spacer. Two routes were developed for the facile preparation of these novel modified amino acids: the direct method, which can only be applied to secondary amines, and the indirect method (transamination reaction), which can be applied to any amino acid or ester.
Alnabari
M
M
Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Bittner
S
S
D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry*; D016227:Benzoquinones / Q000138:chemical synthesis / Q000737:chemistry*; D002703:Chloranil / Q000737:chemistry; D007202:Indicators and Reagents / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D009285:Naphthoquinones / Q000737:chemistry
D000596:Amino Acids; D016227:Benzoquinones; D007202:Indicators and Reagents; D009285:Naphthoquinones; D002703:Chloranil; C004532:quinone; C007332:dichlone