title: A novel anaesthetic regimen for surgical procedures in guineapigs.
abstract: A combination of tiletamine/zolazepam, xylazine and butorphanol provides deep surgical, long-duration anaesthesia in guineapigs with a smooth induction and recovery period. The described dosages mainly affect the respiratory functions and blood gas parameters, with a minor-to-moderate effect on the cardiovascular system.
authors.affiliation: Veterinary Sciences, AstraZeneca R&D Lund, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Jacobson
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000494:pharmacology*; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000494:pharmacology*; D000758:Anesthesia / Q000379:methods / Q000662:veterinary; D000778:Anesthetics, Dissociative; D000818:Animals; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001569:Benzodiazepines; D002077:Butorphanol / Q000008:administration & dosage / Q000494:pharmacology*; D006168:Guinea Pigs; D008297:Male; D013514:Surgical Procedures, Operative / Q000662:veterinary*; D013992:Tiletamine; D014991:Xylazine / Q000008:administration & dosage / Q000494:pharmacology*; D015041:Zolazepam / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D000316:Adrenergic alpha-Agonists; D000701:Analgesics, Opioid; D000778:Anesthetics, Dissociative; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D014991:Xylazine; D013992:Tiletamine; D015041:Zolazepam; D002077:Butorphanol