title: [Multiorgan resection in T4 colonic adenocarcinoma. Report of a case].
abstract: BACKGROUND
  Colorectal cancer is the second among gastrointestinal malignancies in Mexico Locally advanced disease or metastatic lesions are frequently found. To resect or not such a tumor is a difficult decision.
  
  
  OBJECTIVE
  To report a case of colon cancer with multivisceral invasion resected and to review the published information.
  
  
  METHODS
  A 43 year-old Mexican male with rectal bleeding and weight loss with a tumor located in transverse colon with direct invasion to stomach. CT scan demonstrated invasion to spleen and pancreas. En-bloc radical-extended right colectomy, total gastrectomy, distal pancreatectomy, splenectomy and left adrenalectomy was performed. Adjuvant chemotherapy was used. At 12-month follow-up he is asymptomatic, without neoplasic activity and with good quality of life.
  
  
  CONCLUSIONS
  An aggressive multiorganic resection in T4 colorectal tumors is justified in selected cases. The high morbidity and mortality of these procedures must be evaluated individually, and if permissive must be performed.
authors.affiliation: Departamento de Gastroenterología, Instituto Nacional de Cancerología, San Fernando 22, Colonia Toriello Guerra, México D.F. 14000, México. lonate@dfl.telmex.net.mx
authors.forename: L F
authors.initials: LF
authors.lastname: Oñate-Ocaña
authors.forename: R
authors.initials: R
authors.lastname: Herrera-Goepfert
authors.forename: V
authors.initials: V
authors.lastname: Aiello-Crocifoglio
authors.forename: R
authors.initials: R
authors.lastname: Mondragón-Sánchez
authors.forename: J M
authors.initials: JM
authors.lastname: Ruiz-Molina
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000315:Adrenalectomy; D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D003082:Colectomy; D003110:Colonic Neoplasms / Q000473:pathology / Q000601:surgery*; D005472:Fluorouracil / Q000627:therapeutic use; D005743:Gastrectomy; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage / Q000627:therapeutic use; D008197:Lymph Node Excision; D008297:Male; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010179:Pancreas / Q000473:pathology / Q000601:surgery; D010180:Pancreatectomy; D012074:Remission Induction; D013154:Spleen / Q000473:pathology / Q000601:surgery; D013156:Splenectomy; D013270:Stomach / Q000473:pathology / Q000601:surgery
chemical_list: D000964:Antimetabolites, Antineoplastic; D002955:Leucovorin; D005472:Fluorouracil