Anti-inflammatory mechanisms of methotrexate in rheumatoid arthritis.
Cutolo
M
M
Division of Rheumatology Department of Internal Medicine University of Genova Viale Benedetto XV,6 16136 Genova, Italy. mcutolo@unige.it
Sulli
A
A
Pizzorni
C
C
Seriolo
B
B
Straub
R H
RH
D000241:Adenosine / Q000378:metabolism; D000818:Animals; D018501:Antirheumatic Agents / Q000378:metabolism / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D002453:Cell Cycle / Q000187:drug effects; D000242:Cyclic AMP / Q000378:metabolism; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D016207:Cytokines / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008666:Metalloendopeptidases / Q000187:drug effects / Q000378:metabolism; D008727:Methotrexate / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D019014:fas Receptor / Q000187:drug effects / Q000378:metabolism
D018501:Antirheumatic Agents; D016861:Cyclooxygenase Inhibitors; D016207:Cytokines; D019014:fas Receptor; D000242:Cyclic AMP; D008666:Metalloendopeptidases; D000241:Adenosine; D008727:Methotrexate