A series of three (E)-2-alkylidene-1,4-di-p-tosyl-1,2,3,4-tetrahydroquinoxaline compounds.
The three title quinoxaline derivatives, (E)-2-(4-methylbenzylidene)-1,4-di-p-tosyl-1,2,3,4-tetrahydroquinoxaline, C30H28N2O4S2, (II), (E)-2-(4-methoxybenzylidene)-1,4-di-p-tosyl-1,2,3,4-tetrahydroquinoxaline, C30H28N2O5S2, (III), and (E)-2-(3-chlorobenzylidene)-1,4-di-p-tosyl-1,2,3,4-tetrahydroquinoxaline, C29H25ClN2O4S2, (IV), were synthesized by palladium-catalyzed hetero-annulation. The E configuration of the exocyclic double bond in the three compounds has been established by the present X-ray study. The saturated part of the quinoxaline moiety in all three compounds assumes a distorted chair conformation. The numerical descriptors indicate a high degree of isostructurality between compounds (II) and (III), but no isostructurality with compound (IV).
Banerjee
S
S
Department of Physics, Jadavpur University, Calcutta 700 032, India.
Mukherjee
A K
AK
Mukhopadhyay
R
R
Kundu
N G
NG
Welch
A J
AJ
D018360:Crystallography, X-Ray; D008958:Models, Molecular; D008968:Molecular Conformation; D011810:Quinoxalines / Q000737:chemistry*; D013329:Structure-Activity Relationship; D014105:Tosyl Compounds / Q000737:chemistry
D011810:Quinoxalines; D014105:Tosyl Compounds