[Vitamin A metabolism and retinal degeneration].
Vitamin A plays an important role in the pathogenesis and during the course of retinal degenerations. Following a brief overview of the metabolic pathway of Vitamin A from the entrance into the body to the arrival in retinal target structures, the most important retinal degenerations that are related to the Vitamin A-metabolism are presented. Ways of prevention or therapy of such diseases are discussed in the light of the still incomplete knowledge about basic mechanisms of retinol transport and metabolism.
Seeliger
M
M
Universitäts-Augenklinik, Abteilung für Pathophysiologie des Sehens und Neuroophthalmologie, Tübingen. see@uni-tuebingen.de
Biesalski
H K
HK
D006801:Humans; D010786:Photoreceptor Cells / Q000503:physiopathology; D010857:Pigment Epithelium of Eye / Q000503:physiopathology; D012162:Retinal Degeneration / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D014801:Vitamin A / Q000008:administration & dosage / Q000378:metabolism*; D014802:Vitamin A Deficiency / Q000150:complications* / Q000503:physiopathology / Q000517:prevention & control
D014801:Vitamin A