Fourteen-membered ring macrolides inhibit vascular cell adhesion molecule-1 messenger RNA induction preventing neutrophil-induced lung injury and fibrosis in bleomycin-challenged mice.
Azuma
A
A
Fourth Department of Internal Medicine, Nippon Medical School, Bunkyo-ku, Tokyo, Japan. azuma/med4@nms.ac.jp
Li
Y
Y
Usuki
J
J
Aoyama
A
A
Enomoto
T
T
Kudoh
S
S
D000818:Animals; D018942:Macrolides / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D011658:Pulmonary Fibrosis / Q000188:drug therapy / Q000503:physiopathology*; D012333:RNA, Messenger / Q000378:metabolism*; D019010:Vascular Cell Adhesion Molecule-1 / Q000378:metabolism*
D018942:Macrolides; D012333:RNA, Messenger; D019010:Vascular Cell Adhesion Molecule-1