title: Some applications of a chiral fluorometric reagent, (S)-TBMB carboxylic acid.
abstract: Molecular design and applications of a fluorometric chiral agent, (S)-TBMB carboxylic acid, are briefly reviewed. The agent, possessing an asymmetric 1,3-benzodioxole skeleton, was designed as a novel class of chiral agent that functions also as a benzoate chromophore for exciton chirality CD methods. The utility of this agent has been demonstrated in an application to determine enantiomeric amino acids, acyl-sn-glycerols, glycosyl-sn-glycerols, and other chiral alcohols and amines.
authors.affiliation: Kansei Fukushi Research Center, Tohoku Fukushi University, 1-8-1 Kunimi, Aoba-ku, Sendai 981-0943, Japan. meguro@tfu-mail.tfu.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Meguro
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: C
authors.initials: C
authors.lastname: Bai
authors.forename: Y
authors.initials: Y
authors.lastname: Nishida
authors.forename: H
authors.initials: H
authors.lastname: Ohrui
mesh_terms: D000596:Amino Acids / Q000032:analysis* / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002942:Circular Dichroism; D004149:Dioxoles / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005990:Glycerol / Q000031:analogs & derivatives / Q000032:analysis / Q000737:chemistry; D008968:Molecular Conformation; D013237:Stereoisomerism; D013402:Sugar Alcohols / Q000032:analysis* / Q000737:chemistry
chemical_list: C435704:2-tert-butyl-2-methyl-1,3-benzodioxole-4-carboxylic acid; D000596:Amino Acids; D002264:Carboxylic Acids; D004149:Dioxoles; D005456:Fluorescent Dyes; D013402:Sugar Alcohols; D005990:Glycerol