Guillain-Barré syndrome in a child with acute lymphoblastic leukemia.
A 4-year-old boy with acute lymphoblastic leukemia receiving maintenance treatment developed quadriparesis, facial palsy, difficulty in swallowing, and hypertension following a respiratory infection and candida septicemia. Examination of the cerebrospinal fluid was normal initially but later showed albuminocytologic dissociation, the characteristic finding of Guillain-Barré syndrome. Complete recovery occurred after treatment with intravenous immunoglobulin. Differential diagnosis of Guillain-Barré syndrome from vincristine toxicity in patients with leukemia and possible association with the infections are discussed.
Aral
Y Z
YZ
Gazi University Medical Faculty, Department of Pediatric Hematology, Ankara, Turkey. yuziar_12@yahoo.com
Gursel
T
T
Ozturk
G
G
Serdaroglu
A
A
D002675:Child, Preschool; D020275:Guillain-Barre Syndrome / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D014750:Vincristine / Q000009:adverse effects
D014750:Vincristine