title: Optic nerve lesion following neuroborreliosis: a case report.
abstract: OBJECTIVE
  Neuroborreliosis may cause various neuro-ophthalmological complications. We describe a case with a bilateral optic neuropathy.
  
  
  METHODS
  A 58-year-old female developed facial paresis six weeks after an insect bite. One week later she developed bilateral optic disc swelling with haemorrhages and nerve fibre bundle defects in the lower visual field of the left eye. In CSF and serum, raised IgM and IgG titres to Borrelia burgdorferi were found. Systemic antibiotic treatment led to improvement of the vision and facial paresis, but not all visual field defects resolved, probably due to ischemic lesions of the optic disc.
  
  
  CONCLUSIONS
  In optic nerve lesions due to neuroborreliosis it is difficult to distinguish between inflammatory and ischemic lesions. This patient demonstrated features of an ischemic optic nerve lesion.
authors.affiliation: Ahaus Eye Hospital, Germany. carsten@dr-burkhard.de
authors.forename: C
authors.initials: C
authors.lastname: Burkhard
authors.forename: M
authors.initials: M
authors.lastname: Gleichmann
authors.forename: H
authors.initials: H
authors.lastname: Wilhelm
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis; D025065:Borrelia burgdorferi / Q000276:immunology / Q000302:isolation & purification*; D002443:Ceftriaxone / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D005158:Facial Paralysis / Q000209:etiology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007262:Infusions, Intravenous; D020852:Lyme Neuroborreliosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010211:Papilledema / Q000209:etiology; D012166:Retinal Hemorrhage / Q000209:etiology; D014794:Visual Fields
chemical_list: D000907:Antibodies, Bacterial; D002511:Cephalosporins; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D002443:Ceftriaxone