[Effect of pineal peptides on neuroendocrine system after pinealectomy].
Removal of the pineal gland leads to structural and functional rearrangement of gastric endocrine cells and thyroid C-cells in albino rats, as was shown by immunohistological methods and morphometry. Injection of pineal peptides epithalone and epithalamine eliminated these changes. Biological activity of epithalone is believed to be higher than that of epithalamine.
Khavinson
V Kh
VKh
St. Petersburg Institute of Bioregulation and Gerontology, 119110, St. Petersburg.
Kvetnoĭ
I M
IM
Popuchiev
V V
VV
Iuzhakov
V V
VV
Kotlova
L N
LN
D001078:APUD Cells / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D008297:Male; D009842:Oligopeptides / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology / Q000502:physiology*; D010870:Pineal Gland / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013961:Thyroid Gland / Q000166:cytology / Q000187:drug effects / Q000502:physiology*
D009842:Oligopeptides; D010455:Peptides; C027437:epithalamin; C421253:alanyl-glutamyl-aspartyl-glycine