Hypersensitivity syndrome (DRESS) and meningoencephalitis associated with nevirapine therapy.
The DRESS (drug rash with eosinophilia and systemic symptoms) syndrome is a serious condition that has been reported in association with various drugs, such as allopurinol, sulfonamides and aromatic anticonvulsants. Recently the condition has been described in HIV-infected patients taking antiretroviral agents. We report the first case, to our knowledge, of DRESS syndrome complicated by meningoencephalitis associated with nevirapine therapy.
Lanzafame
M
M
Unità Operativa di Malattie Infettive, Ospedale Civile di Legnago, Verona, Italy.
Rovere
P
P
De Checchi
G
G
Trevenzoli
M
M
Turazzini
M
M
Parrinello
A
A
D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003875:Drug Eruptions / Q000150:complications / Q000209:etiology; D004342:Drug Hypersensitivity / Q000150:complications / Q000209:etiology*; D004802:Eosinophilia / Q000139:chemically induced / Q000150:complications; D005076:Exanthema / Q000139:chemically induced / Q000150:complications; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000139:chemically induced* / Q000150:complications; D019829:Nevirapine / Q000009:adverse effects* / Q000627:therapeutic use; D013577:Syndrome
D019380:Anti-HIV Agents; D019829:Nevirapine