title: Effects of Isatis cappadocica on humoral immune responses.
abstract: The effects of a 20% ethanol extract of Isatis cappadocica on humoral immune responses in rabbits and mice were studied. After intraperitoneal injection of 0.25 and 0.5 g/kg, a dose-dependent effect was observed. In particular, the dose of 0.25 g/kg suppressed the primary immune responses, while the dose of 0.5 g/kg stimulated the secondary immune responses.
authors.affiliation: Immunology Department, Medical School, Shahid Beheshti University of Medical Science, P.O. Box 19835-145, Tehran, Iran. okhravi@khayam.ut.ac.ir
authors.forename: R
authors.initials: R
authors.lastname: Rezaeipoor
authors.forename: L
authors.initials: L
authors.lastname: Ziaei Sanei
authors.forename: M
authors.initials: M
authors.lastname: Kamalinejad
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D019607:Brassicaceae; D004305:Dose-Response Relationship, Drug; D005260:Female; D006386:Hemagglutination Tests; D007958:Leukocyte Count; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009929:Organ Size / Q000187:drug effects; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology; D010946:Plants, Medicinal; D011817:Rabbits; D013154:Spleen / Q000187:drug effects
chemical_list: D010936:Plant Extracts