title: Effects of PCBs sorbed to algal paste and sediments on the stress protein response (HSP70 family) in the eastern oyster, Crassostrea virginica.
abstract: This study examined the stress protein response (HSP70 family) of reproductively inactive oysters fed 0.7 g algal paste containing 0, 0.35 and 3.5 micrograms polychlorinated biphenyls (PCBs) daily. A second set of treatment groups investigated the combined effect of PCBs and sediments (0.3 g sediments daily per oyster) on HSP70 response. After 8 weeks of PCB exposure, oyster tissues (mantle and gill) were sampled and analyzed for HSP70. Preliminary results did not show a significant effect in HSP70 response in oysters fed PCB sorbed to algal paste, albeit PCBs accumulated up to 1342 ng/g dry weight in the mantle, and up to 180 ng/g dry weight in gill tissues. However, the addition of sediments caused a significant increase in HSP70 levels of gills and mantle, although the mantle was less sensitive to the sediments.
authors.affiliation: Department of Environmental Sciences, School of Marine Sciences, Virginia Institute of Marine Sciences, College of William and Mary, Gloucester Point, VA 23062, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Cruz-Rodríguez
authors.forename: A J
authors.initials: AJ
authors.lastname: Baucum
authors.forename: P
authors.initials: P
authors.lastname: Soudant
authors.forename: F L
authors.initials: FL
authors.lastname: Chu
authors.forename: R C
authors.initials: RC
authors.lastname: Hale
mesh_terms: D000818:Animals; D056890:Eukaryota; D019015:Geologic Sediments; D005880:Gills / Q000187:drug effects / Q000378:metabolism; D018840:HSP70 Heat-Shock Proteins / Q000096:biosynthesis*; D010125:Ostreidae / Q000187:drug effects* / Q000378:metabolism*; D011078:Polychlorinated Biphenyls / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D018840:HSP70 Heat-Shock Proteins; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls