title: Image-guided acoustic therapy.
abstract: The potential role of therapeutic ultrasound in medicine is promising. Currently, medical devices are being developed that utilize high-intensity focused ultrasound as a noninvasive method to treat tumors and to stop bleeding (hemostasis). The primary advantage of ultrasound that lends the technique so readily to use in noninvasive therapy is its ability to penetrate deep into the body and deliver to a specific site thermal or mechanical energy with submillimeter accuracy. Realizing the full potential of acoustic therapy, however, requires precise targeting and monitoring. Fortunately, several imaging modalities can be utilized for this purpose, thus leading to the concept of image-guided acoustic therapy. This article presents a review of high-intensity focused ultrasound therapy, including its mechanisms of action, the imaging modalities used for guidance and monitoring, some current applications, and the requirements and technology associated with this exciting and promising field.
authors.affiliation: Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, Washington 98105-6698, USA. adasi@u.washington.edu
authors.forename: S
authors.initials: S
authors.lastname: Vaezy
authors.forename: M
authors.initials: M
authors.lastname: Andrew
authors.forename: P
authors.initials: P
authors.lastname: Kaczkowski
authors.forename: L
authors.initials: L
authors.lastname: Crum
mesh_terms: D006801:Humans; D013813:Therapy, Computer-Assisted / Q000379:methods*; D014464:Ultrasonic Therapy / Q000379:methods*; D014463:Ultrasonography / Q000379:methods