title: Drug therapy: safety, effectiveness, and economics.
abstract: The problems of safety, effectiveness and economics of a drug therapy are discussed. Adverse drug reactions (ADR) represent not only a humanistic problem but also an epidemiological and economic one. The incidents and costs of ADRs are described, as well as pharmacovigilance and pharmacoeconomics as a tool of rationalizing the expenditures on health care.
authors.affiliation: Department of Toxicology, Faculty of Farmacy Medical College, Jagiellonian University, Kraków, Poland. mfbrandy@cyf-kr.edu.pl
authors.forename: J
authors.initials: J
authors.lastname: Brandys
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods*; D003362:Cost-Benefit Analysis; D004345:Drug Industry / Q000191:economics / Q000592:standards; D016903:Drug Monitoring / Q000379:methods; D064420:Drug-Related Side Effects and Adverse Reactions; D017850:Economics, Pharmaceutical / Q000639:trends*; D006801:Humans; D017063:Outcome Assessment, Health Care; D019057:Quality-Adjusted Life Years