[Effect of radiation with 60Co on RBC membrane elastic shear modulus and membrane viscosity].
RBC membrane shear elastic modulus and membrane viscosity are two important indexes reflecting RBC membrane viscoelasticity. Their variation was investigated in this study after rabbits were radiated with 60Co. With a new ektacytometer, we measured the small deformation index (DId) and the half-time of deformation relaxation (t0.5) of RBC in flow field then we calculated RBC membrane shear elastic modulus and membrane viscosity. We found that the value of RBC membrane shear elastic modulus and membrane viscosity continuously increased from 0 to 16th day then continuously decreased and tended to be stable on 60th day or so. The reason may lie in the variation of proportion of new and old RBC in blood and variation of microconformation of RBC membrane after rabbits were radiated with 60Co.
Chen
K
K
Department of Medical Physics, Peking University Health Science Center, Beijing 100083.
Xie
L
L
Zhangping
Yao
W
W
Wen
Z
Z
Yan
Z
Z
D000818:Animals; D003037:Cobalt Radioisotopes; D004548:Elasticity / Q000528:radiation effects; D004910:Erythrocyte Membrane / Q000502:physiology / Q000528:radiation effects*; D005260:Female; D008297:Male; D011817:Rabbits; D014783:Viscosity / Q000528:radiation effects
D003037:Cobalt Radioisotopes