[Clinical study on the forced oscillatory pulmonary function test].
OBJECTIVE
To discuss the change of airway resistance and phase angle (phi) in normal subjects, patients with COPD, asthma and pulmonary fibrosis when the new technique of the forced oscillatory pulmonary function test was applied to measure them as well as the change of pulmonary function of patients with asthma after using bronchodilator.


METHODS
Use Custo-vitm forced oscillation device manufactured in Germany to determine airway resistance and phase angle and to compare their statistical differences between normal subjects and patients with pulmonary disease, and then comparing the improvement rates of their FEV1, F-V curve and airway resistance in patients with asthma after inhaling bricasol.


RESULTS
The measurements of group COPD and asthma were significantly higher than those of normal group (P < 0.05), and there were obvious frequency dependence in these two groups. The results of phase angle in each group of patients were significantly lower than those of normal group (P < 0.05), and the group of patients with pulmonary fibrosis only demonstrates a decrease in phase angle, and the improvement rate of airway resistance in patients with asthma after inhaling bricasol was significantly higher than FEV1 and F-V curve (P < 0.05).


CONCLUSIONS
Forced oscillation is a convenient, quick, and noninvasive new method when applied to measure airway resistance and phase angle. It is especially suitable for patients with severe COPD and better than conventional pulmonary function test in observing therapeutic effect in asthma.
Wang
H
H
Pulmonary Function Laboratory, Tianjin Chest Hospital, Tianjin 300051.
Wei
H
H
Zhao
L
L
D000328:Adult; D000368:Aged; D000403:Airway Resistance; D001249:Asthma / Q000503:physiopathology*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009991:Oscillometry; D011658:Pulmonary Fibrosis / Q000503:physiopathology*; D012129:Respiratory Function Tests / Q000379:methods*