title: A psychophysiological marker of attention deficit/hyperactivity disorder (ADHD)--defining the EEG consistency index.
abstract: This study continues our research to further validate the idea that ADHD (Attention Deficit/Hyperactivity Disorder) interferes with transition from one task to another and this interference can be quantified by a Consistency Index (CI) derived from a specific mathematical representation of EEG data. We reanalyze 32 previously reported data sets present new data for 35 boys and girls, ages 7-12, ADHD or control. Each data set contains EEG, recorded and digitized while participants perform consecutive 10-min tasks: video, reading, and math. For boys, the CI in ADHD was four times lower than in controls, p < .005, for girls this difference was two times, p < .05. ADHD/control classification based on the CI coincided with the DSM-IV criteria for 88% of the boys and for 67% of the girls. Post hoc analysis indicated that the classification utility of the CI diminished with age. A CI below 40% could be a discriminating, reliable, and reproducible marker of ADHD in young boys.
authors.affiliation: Center for Behavioral Medicine Research, University of Virginia Health System, Box 800137, Charlottesville, Virginia 22908, USA. boris@virginia.edu
authors.forename: B
authors.initials: B
authors.lastname: Kovatchev
authors.forename: D
authors.initials: D
authors.lastname: Cox
authors.forename: R
authors.initials: R
authors.lastname: Hill
authors.forename: R
authors.initials: R
authors.lastname: Reeve
authors.forename: R
authors.initials: R
authors.lastname: Robeva
authors.forename: T
authors.initials: T
authors.lastname: Loboschefski
mesh_terms: D001289:Attention Deficit Disorder with Hyperactivity / Q000523:psychology*; D016022:Case-Control Studies; D002648:Child; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D015201:Meta-Analysis as Topic; D011581:Psychological Tests; D011603:Psychophysiology; D017678:Sex Distribution