title: Glucose-6-phosphate dehydrogenase deficiency promotes endothelial oxidant stress and decreases endothelial nitric oxide bioavailability.
authors.affiliation: Whitaker Cardiovascular Institute and Evans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA. jane.leopold@bmc.org
authors.forename: J A
authors.initials: JA
authors.lastname: Leopold
authors.forename: A
authors.initials: A
authors.lastname: Cap
authors.forename: A W
authors.initials: AW
authors.lastname: Scribner
authors.forename: R C
authors.initials: RC
authors.lastname: Stanton
authors.forename: J
authors.initials: J
authors.lastname: Loscalzo
mesh_terms: D000818:Animals; D001011:Aorta; D002417:Cattle; D006152:Cyclic GMP / Q000032:analysis; D003687:Dehydroepiandrosterone / Q000494:pharmacology; D004730:Endothelium, Vascular / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005954:Glucosephosphate Dehydrogenase / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000494:pharmacology; D009249:NADP / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors / Q000378:metabolism; D052250:Nitric Oxide Synthase Type III; D016376:Oligonucleotides, Antisense / Q000235:genetics / Q000494:pharmacology; D018384:Oxidative Stress; D011621:Pteridines / Q000494:pharmacology; D011622:Pterins; D017382:Reactive Oxygen Species / Q000378:metabolism; D014162:Transfection
chemical_list: D004791:Enzyme Inhibitors; D016376:Oligonucleotides, Antisense; D011621:Pteridines; D011622:Pterins; D017382:Reactive Oxygen Species; D009569:Nitric Oxide; D003687:Dehydroepiandrosterone; D009249:NADP; D006861:Hydrogen Peroxide; C016727:sepiapterin; D005954:Glucosephosphate Dehydrogenase; D019001:Nitric Oxide Synthase; D052250:Nitric Oxide Synthase Type III; D006152:Cyclic GMP