title: [Yishen huanshuai recipe retard progression of chronic renal failure].
abstract: OBJECTIVE
  To investigate the effect of Yishen Huanshuai recipe (YSHSR) on the progression of chronic renal failure (CRF).
  
  
  METHODS
  Forty-six patients with CRF were divided into two groups: group A (self-controlled group, n = 18), whose treatment was subdivided into two stages. During the first stage, the patients treated with low protein diet and controlling blood pressure, while in the second stage, YSHSR was given. Group B(n = 28), whose treatment plan was similar with that of group A in second stage. The rate of progression of CRF was estimated by slope of the creatinine reciporcal (dl/mg) with time (month).
  
  
  RESULTS
  Mean slope of the creatinine reciprocal with time from the group A during the first stage was -0.0104 +/- 0.0021, while during the second stage, it was -0.0034 +/- 0.0018. There was significant difference between them (P < 0.05). Mean slope from the group B was -0.0047 +/- 0.0020. There was also significant difference between that from the group B and that from the group A during the first stage (P < 0.05).
  
  
  CONCLUSIONS
  Low protein and controlling blood pressure plus YSHSR therapy could markedly retard the rate of progression of CRF.
authors.affiliation: Guang'anmen Hospital, China Academy of TCM 100053.
authors.forename: D
authors.initials: D
authors.lastname: Yin
authors.forename: X
authors.initials: X
authors.lastname: Dai
authors.forename: X
authors.initials: X
authors.lastname: Rao
mesh_terms: D000328:Adult; D003404:Creatinine / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D004365:Drugs, Chinese Herbal; D003404:Creatinine