Avalanche dynamics of crackle sound in the lung.
We analyze a sequence of short transient sound waves, called "crackles," which are associated with explosive openings of airways during lung inflation. The distribution of time intervals between consecutive crackles Delta(t) shows two regimes of power law behavior. We develop an avalanche model which fits the data over five decades of Delta(t). We find that the regime for large Delta(t) is related to the dynamics of distinct avalanches in a Cayley tree, and the regime for small Delta(t) is determined by the dynamics of crackle propagation within a single avalanche. We also obtain a mean-field solution of the model which provides information about lung inflation.
Alencar
A M
AM
Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA.
Buldyrev
S V
SV
Majumdar
A
A
Stanley
H E
HE
Suki
B
B
D000162:Acoustics; D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D004285:Dogs; D008954:Models, Biological; D015656:Respiratory Mechanics; D012135:Respiratory Sounds / Q000502:physiology*