Management of chronic stable angina pectoris from a sceptic's view point.
Ischaemic heart disease is a leading cause of death in the world. It has clinically defined phases as: Asymptomatic, stable angina, progressive angina and unstable angina. It is important to differentiate patients of angina into those with stable and unstable angina--risk stratification and management differ in the two groups. Risk stratification of patients with stable angina using clinical parameters helps in development of clearer indication of referral for exercise testing and cardiac catheterisation. Chronic stable angina patients with history of documented myocardial infarction of Q waves on ECG should have measurement of left ventricular systolic function (ie, ejection fraction) as it is important for choosing the appropriate medical or surgical therapy. Symptomatic patients with suspected or known coronary artery disease should usually undergo exercise testing to assess the risk of future cardiac events. The treatment of stable angina has two purposes: To prevent myocardial infarction and death and therapy directed towards preventing death. Pharmacotherapy consists of: Aspirin, lipid lowering agents, beta-blockers, nitrates, short acting dihydropyridine calcium antagonists, etc. For surgery, there are two well established approaches of revascularisation. One is coronary artery by-pass grafting and the other is percutaneous transluminal coronary angioplasty. Studies comparing different treatment modalities are elaborated in this article. In conclusion, it can be said that patients having severe symptoms affecting quality of life despite optimal medical therapy should be referred for revascularisation surgery.
Kachru
R
R
Department of Interventional Cardiology, Batra Hospital & Medical Research Centre, New Delhi.
Kaul
U
U
D000787:Angina Pectoris / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003327:Coronary Disease / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D004562:Electrocardiography; D005080:Exercise Test; D006801:Humans; D007194:India; D009203:Myocardial Infarction / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D009204:Myocardial Revascularization; D012008:Recurrence; D012307:Risk Factors; D015996:Survival Rate
D002317:Cardiovascular Agents