title: [Studies on chemical constituents of Polygala arillata buch-ham].
abstract: Two new compounds were isolated from the roots of Polygala arillata Buch-Ham. On the basis of chemical reactions and spectral (UV, IR, MS, 1HNMR, DIFNOE, 13CNMR) analysis, they were identified as 1,3-dihydroxy-2-methoxyxanthone(I) and 7-hydroxy-1-methoxy-2,3-methylenedioxyxanthone(II). Pharmacological study indicated that I and II have inhibitory effect on aldose reductase activity.
authors.affiliation: Department of Medicinal Chemistry of Natural Products, School of Pharmacy, Second Military Medical University, Shanghai 200433.
authors.forename: S L
authors.initials: SL
authors.lastname: Mao
authors.forename: S X
authors.initials: SX
authors.lastname: Liao
authors.forename: J H
authors.initials: JH
authors.lastname: Wu
authors.forename: N
authors.initials: N
authors.lastname: Ling
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.forename: H Q
authors.initials: HQ
authors.lastname: Liang
authors.forename: M Z
authors.initials: MZ
authors.lastname: Liu
mesh_terms: D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D019684:Magnoliopsida / Q000737:chemistry; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014970:Xanthines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D044004:Xanthones
chemical_list: C438033:1,3-dihydroxy-2-methoxy-xanthone; C438034:7-hydroxy-1-methoxy-2,3-methylenedioxy-xanthone; D004365:Drugs, Chinese Herbal; D014970:Xanthines; D044004:Xanthones; D000449:Aldehyde Reductase