[Studies on chemical constituents of Polygala arillata buch-ham].
Two new compounds were isolated from the roots of Polygala arillata Buch-Ham. On the basis of chemical reactions and spectral (UV, IR, MS, 1HNMR, DIFNOE, 13CNMR) analysis, they were identified as 1,3-dihydroxy-2-methoxyxanthone(I) and 7-hydroxy-1-methoxy-2,3-methylenedioxyxanthone(II). Pharmacological study indicated that I and II have inhibitory effect on aldose reductase activity.
Mao
S L
SL
Department of Medicinal Chemistry of Natural Products, School of Pharmacy, Second Military Medical University, Shanghai 200433.
Liao
S X
SX
Wu
J H
JH
Ling
N
N
Chen
H
H
Liang
H Q
HQ
Liu
M Z
MZ
D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D019684:Magnoliopsida / Q000737:chemistry; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D014970:Xanthines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D044004:Xanthones
C438033:1,3-dihydroxy-2-methoxy-xanthone; C438034:7-hydroxy-1-methoxy-2,3-methylenedioxy-xanthone; D004365:Drugs, Chinese Herbal; D014970:Xanthines; D044004:Xanthones; D000449:Aldehyde Reductase