title: HeartMate III: pump design for a centrifugal LVAD with a magnetically levitated rotor.
abstract: A long-term, compact left ventricular assist device (LVAD), the HeartMate III, has been designed and fabricated, featuring a centrifugal pump with a magnetically levitated rotor. The pump has been optimized by in vitro testing to achieve a design point of 7 L/min against 135 mm Hg at high hydrodynamic efficiency (30%) and to be capable of up to 10 L/min under such a load. Furthermore, the pump has demonstrated no mechanical failures, low hemolysis (4-10 mg/dl plasma free Hb), and low thrombogenicity during six (40, 27, 59, 42, 27, and 49-day) in vivo bovine studies.
authors.affiliation: Thoratec Corp, Woburn, Massachusetts 01888-2697, USA.
authors.forename: K
authors.initials: K
authors.lastname: Bourque
authors.forename: D B
authors.initials: DB
authors.lastname: Gernes
authors.forename: H M
authors.initials: HM
authors.lastname: Loree
authors.forename: J S
authors.initials: JS
authors.lastname: Richardson
authors.forename: V L
authors.initials: VL
authors.lastname: Poirier
authors.forename: N
authors.initials: N
authors.lastname: Barletta
authors.forename: A
authors.initials: A
authors.lastname: Fleischli
authors.forename: G
authors.initials: G
authors.lastname: Foiera
authors.forename: T M
authors.initials: TM
authors.lastname: Gempp
authors.forename: R
authors.initials: R
authors.lastname: Schoeb
authors.forename: K N
authors.initials: KN
authors.lastname: Litwak
authors.forename: T
authors.initials: T
authors.lastname: Akimoto
authors.forename: M J
authors.initials: MJ
authors.lastname: Watach
authors.forename: P
authors.initials: P
authors.lastname: Litwak
mesh_terms: D000818:Animals; D002417:Cattle; D006353:Heart-Assist Devices; D008280:Magnetics; D011474:Prosthesis Design; D011673:Pulsatile Flow