Remarkable rate acceleration of Pd(0)-catalyzed hydrogermylation of alkynes and dienes in water.
[reaction: see text] Without the use of hydrophilic cosolvents or phase transfer catalysts, Pd(0)-catalyzed hydrogermylation of alkynes in water provides dienylgermanes efficiently with high stereo- and regioselectivity. The reaction in water proceeds much faster than the reaction under neat conditions. By using an aqueous system, hydrogermylation can be conducted at a low catalyst loading.
Kinoshita
H
H
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 606-8501, Japan.
Nakamura
T
T
Kakiya
H
H
Shinokubo
H
H
Matsubara
S
S
Oshima
K
K
D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D007700:Kinetics; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry*
D000475:Alkenes; D000480:Alkynes; D014867:Water; D010165:Palladium