title: Carotid endarterectomy with bovine patch angioplasty: a preliminary report.
abstract: Carotid endarterectomy with patch angioplasty is a durable procedure for prevention of recurrent neurological symptoms and stroke. However, no definitive study has demonstrated a clear benefit of one class of the patch material over another. The aim of this study was to evaluate the clinical outcome of carotid endarterectomy with bovine pericardium patch in comparison with autologous vein patch. One hundred and twenty-two carotid endarterectomies were performed using patch closure of the arteriotomy with bovine pericardium (61 cases) and autologous vein (61 cases) between September 1995 and June 1999. Though this is not a double-blind type randomized comparative study, effort was made to achieve a 1:1 ratio in sequence with a few exceptions such as non-available veins at time of surgery or for future use. In bovine pericardium patch closure group, the mean total operating time was significantly shorter than autologous vein closure group (P<0.01), but the mean carotid clamping time was similar in both groups, regardless of the use of shunt. The incidence of postoperative local complications including groin wound was less in bovine pericardium patch closure group. The patients were followed with duplex scans in one month post-CEA and 6 months interval thereafter. During the follow-up period, three patients developed non-critical stenosis (two in bovine and one in vein patch), and one aneurysmal dilation occurred in vein patch group. The incidence of restenosis was similar in both groups. Although this is a preliminary report, it is concluded that the results of carotid angioplasty using bovine pericardium compare favorably with autologous vein.
authors.affiliation: Division of Vascular Surgery, University of Ulsan Medical College, Asan Medical Center, Seoul, South Korea. gekim7@amc.seoul.kr
authors.forename: G E
authors.initials: GE
authors.lastname: Kim
authors.forename: T W
authors.initials: TW
authors.lastname: Kwon
authors.forename: Y P
authors.initials: YP
authors.lastname: Cho
authors.forename: D K
authors.initials: DK
authors.lastname: Kim
authors.forename: H S
authors.initials: HS
authors.lastname: Kim
mesh_terms: D000368:Aged; D017130:Angioplasty / Q000379:methods; D000818:Animals; D002340:Carotid Artery Diseases / Q000150:complications / Q000601:surgery; D002417:Cattle; D016894:Endarterectomy, Carotid; D005260:Female; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007601:Jugular Veins / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D008875:Middle Aged; D018408:Patch-Clamp Techniques / Q000379:methods*; D010496:Pericardium / Q000000981:diagnostic imaging / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D012501:Saphenous Vein / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex