Regulation of the alpha-secretase ADAM10 by its prodomain and proprotein convertases.
Anders
A
A
Institute of Biochemistry, Johannes Gutenberg-University Mainz, D-55128 Mainz, Germany.
Gilbert
S
S
Garten
W
W
Postina
R
R
Fahrenholz
F
F
D053829:Amyloid Precursor Protein Secretases; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D016282:Aspartic Acid Endopeptidases; D015153:Blotting, Western; D002417:Cattle; D002460:Cell Line; D004622:Embryo, Mammalian; D010450:Endopeptidases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D004789:Enzyme Activation; D045683:Furin; D006801:Humans; D007668:Kidney; D016296:Mutagenesis; D011498:Protein Precursors / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism; D013329:Structure-Activity Relationship; D013381:Subtilisins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D014162:Transfection
D016564:Amyloid beta-Protein Precursor; D011498:Protein Precursors; D011994:Recombinant Proteins; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; C099101:PCSK7 protein, human; D013381:Subtilisins; D045683:Furin; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human