title: [Biochemical mediators of inflammation].
abstract: Inflammatory processes are the physiological response of the organism to different stimuli such as trauma, infections or immunological reactions. The events leading to inflammation are characterized by leukocytes adhesion to the endothelium, diapedesis and migration, cells activation and tissue remodelling. These processes are initiated and regulated by a great variety of inflammatory mediators including cytokines, prostanoids, leukotrienes, neuropeptides, reactive oxygen and nitrogen species, complement components, coagulation factors and metalloproteases. This paper is devoted to the description of the major local effects of these mediators in the inflammatory reaction.
authors.affiliation: Université de Liège, Unité d'Exploration du Métabolisme de l'Os et du Cartilage.
authors.forename: Y
authors.initials: Y
authors.lastname: Henrotin
authors.forename: G
authors.initials: G
authors.lastname: Deby-Dupont
authors.forename: J Y
authors.initials: JY
authors.lastname: Reginster
mesh_terms: D001779:Blood Coagulation Factors / Q000494:pharmacology; D002448:Cell Adhesion; D002465:Cell Movement; D016207:Cytokines / Q000494:pharmacology*; D005609:Free Radicals; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D007962:Leukocytes / Q000276:immunology / Q000502:physiology*; D008666:Metalloendopeptidases / Q000378:metabolism
chemical_list: D001779:Blood Coagulation Factors; D016207:Cytokines; D005609:Free Radicals; D008666:Metalloendopeptidases