title: Imaging longitudinal cardiac strain on short-axis images using strain-encoded MRI.
abstract: This article presents a new method for measuring longitudinal strain in a short-axis section of the heart using harmonic phase magnetic resonance imaging (HARP-MRI). The heart is tagged using 1-1 SPAMM at end-diastole with tag surfaces parallel to a short-axis imaging plane. Two or more images are acquired such that the images have different phase encodings in a direction orthogonal to the image plane. A dense map of the longitudinal strain can be computed from these images using a simple, fast computation. Simulations are conducted to study the effect of noise and the choice of out-of-plane phase encoding values. Longitudinal strains acquired from a normal human male are shown.
authors.affiliation: Department of Radiology, The Johns Hopkins University, Baltimore, Maryland 21287-0845, USA. nael@jhu.edu
authors.forename: N F
authors.initials: NF
authors.lastname: Osman
authors.forename: S
authors.initials: S
authors.lastname: Sampath
authors.forename: E
authors.initials: E
authors.lastname: Atalar
authors.forename: J L
authors.initials: JL
authors.lastname: Prince
mesh_terms: D000328:Adult; D002320:Cardiovascular Physiological Phenomena; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male