title: Khat induced hemorrhoidal disease in Yemen.
abstract: OBJECTIVE
  The aim of this study was to evaluate the potential association between the habit of khat chewing and the development of hemorrhoidal disease
  
  
  METHODS
  Four hundred and seventy four individuals (373 men and 101 women) with ages ranging from 17 to 80 years were divided into 2 groups. Group 1 (n=247) chronic khat chewers. Group 2 (n=200) non-khat chewers. Data was collected regarding chewing habits, colorectal symptoms, abdominal, proctoscopic, and operative findings.
  
  
  RESULTS
  The key difference between the 2 groups was the incidence of hemorrhoids and hemorrhoidectomy. In the chronic khat chewers group: 169 (62%) had hemorrhoids. Of these 124 (45.4%) underwent hemorrhoidectomy. In the control group there is 8 (4%) had hemorrhoids and one patient underwent hemorrhoidectomy (0.5%). P-value (0.05).
  
  
  CONCLUSIONS
  The study demonstrated a significant association between the habit of khat chewing and the development of hemorrhoidal disease.
authors.affiliation: Department of Surgery, Faculty of Medicine, Sana'a University, Sana'a, Republic of Yemen. HADRANI@y.net.ye
authors.forename: A M
authors.initials: AM
authors.lastname: Al-Hadrani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D029754:Catha; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D002908:Chronic Disease; D003248:Constipation / Q000139:chemically induced / Q000150:complications; D003906:Developing Countries; D005260:Female; D006484:Hemorrhoids / Q000139:chemically induced* / Q000453:epidemiology / Q000601:surgery; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000009:adverse effects*; D012307:Risk Factors; D017678:Sex Distribution; D019966:Substance-Related Disorders / Q000150:complications*; D015006:Yemen / Q000453:epidemiology
chemical_list: D000697:Central Nervous System Stimulants; D010936:Plant Extracts