[The concentration of IgE antibodies in patients with cystic fibrosis].
The aim of the study was to evaluate the total IgE levels and correlation between total IgE concentration in CF and allergy rhinitis patients and in healthy donors, as well as estimation of the activity of some groups of allergens by measurement of specific IgE concentration. The purpose of the study was to estimate correlation between concentration of specific IgE and skin prick tests. The concentration of total and specific IgE was measured by immunoassay. The study groups contained 16 with CF and 10 with allergy rhinitis patients, the control group contain 15 healthy donors. The highest concentration of total IgE we noted in rhinitis subjects, statistically higher than in CF patients and in the control group. The analysis of the concentration of specific IgE showed that allergens as dermatophagoides, food and grasses are the most effective in CF patients. We did not found correlation between specific IgE level and skin prick tests.
Białek
S
S
Katedra i Zakład Biochemii i Chemii Klinicznej AM w Warszawie.
Krzeski
A
A
Baltaziuk
H
H
Kapiszewska
D
D
Białek
K
K
Bagieńska
A
A
Pachecka
J
J
D000293:Adolescent; D000328:Adult; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications / Q000276:immunology* / Q000378:metabolism*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology* / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D012882:Skin Tests
D007073:Immunoglobulin E