Steroid-induced mania in an adolescent: risk factors and management.
Few studies have clearly defined the risk factors and management of steroid-induced mania, particularly in children and adolescents. The case study of a 15-year-old woman with steroid-induced mania is examined to delineate risk factors and management. Genetic predisposition to mood disorders, previous exposure to steroids and the concomitant use of clarithromycin are potential risk factors. Mood stabilizers such as lithium and/or valproic acid may be useful in the acute and prophylactic treatment of steroid-induced mania.
Couturier
J
J
University of Western Ontario, London, Ontario N5Y 4L3, Canada. jlcoutur@julian.uwo.ca
Steele
M
M
Hussey
L
L
Pawliuk
G
G
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000235:genetics / Q000628:therapy; D017291:Clarithromycin / Q000627:therapeutic use; D004347:Drug Interactions; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use; D012307:Risk Factors
D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D017291:Clarithromycin; D011241:Prednisone