DNA relaxation and cleavage assays to study topoisomerase I inhibitors.
Bailly
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INSERM U-524, and Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret IRCL, 59045 Lille, France.
D001483:Base Sequence; D001665:Binding Sites; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D004262:DNA Restriction Enzymes; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D009690:Nucleic Acid Conformation / Q000187:drug effects; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D059004:Topoisomerase I Inhibitors
D004791:Enzyme Inhibitors; D009838:Oligodeoxyribonucleotides; D059004:Topoisomerase I Inhibitors; D004247:DNA; D004262:DNA Restriction Enzymes