title: Attentional asymmetry in schizophrenia: disengagement and inhibition of return deficits.
abstract: This research examined 2 components of visual orienting in medicated schizophrenia patients: the validity effect and the inhibition of return (IOR). In the 1st experiment, patients showed the expected asymmetry in orienting attention, that is, larger validity effect in the right visual field than in the left. However, this asymmetry was due to a deficit in facilitatory processes rather than a disengagement deficit. In addition, patients showed a deficit in IOR. In the 2nd experiment, a 2nd central cue for summoning attention, explicitly, back to the center was used. In this experiment, normal IOR in schizophrenia patients was found. Because it was shown that schizophrenia patients do not have a disengagement deficit, IOR possibly could not be observed because of the increased facilitation in that location. It was proposed that the abnormality in visual attention in schizophrenia is due to a deficit in inhibitory processes.
authors.affiliation: Department of Behavioral Sciences and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel. sapira@bgumail.bgu.ac.il
authors.forename: A
authors.initials: A
authors.lastname: Sapir
authors.forename: A
authors.initials: A
authors.lastname: Henik
authors.forename: M
authors.initials: M
authors.lastname: Dobrusin
authors.forename: E Y
authors.initials: EY
authors.lastname: Hochman
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001288:Attention / Q000502:physiology*; D003463:Cues; D005260:Female; D005403:Fixation, Ocular; D006801:Humans; D007266:Inhibition, Psychological; D008297:Male; D008875:Middle Aged; D010468:Perceptual Disorders / Q000175:diagnosis / Q000209:etiology*; D011930:Reaction Time; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*
chemical_list: D014150:Antipsychotic Agents