title: Rosai-Dorfman disease presenting with isolated bilateral orbital masses: report of two cases.
abstract: Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a rare benign idiopathic proliferative disease of phagocytic histiocytes. Approximately 80% of patients present with painless massive cervical lymphadenopathy. Isolated extranodal involvement is relatively uncommon. Two cases of Rosai-Dorfman disease are reported: one with isolated bilateral orbital involvement and one with marked cervical lymphadenopathy and multiple dural-based and intraventricular masses.
authors.affiliation: Department of Radiology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0030, USA.
authors.forename: E
authors.initials: E
authors.lastname: Wang
authors.forename: Y
authors.initials: Y
authors.lastname: Anzai
authors.forename: A
authors.initials: A
authors.lastname: Paulino
authors.forename: J
authors.initials: J
authors.lastname: Wong
mesh_terms: D000328:Adult; D001706:Biopsy; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology; D004388:Dura Mater / Q000000981:diagnostic imaging / Q000473:pathology; D005094:Exophthalmos / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D009361:Neoplasm Invasiveness; D009916:Orbital Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed