Utility of Etest in choosing appropriate agents to treat fungal keratitis.
OBJECTIVE
To evaluate the utility of Etest in choosing the appropriate treatment of fungal keratitis.


METHODS
Etest was used to determine the drug sensitivities of isolates from the eyes of three patients with fungal keratitis, and the clinical outcomes of treatment with selected drugs were evaluated.


RESULTS
In all cases, drug sensitivity demonstrated by Etest accorded with clinical efficacy of the drugs.


CONCLUSIONS
The results in these cases suggest that evaluating drug sensitivities with Etest is an efficient means of selecting optimal pharmacotherapy for fungal keratitis.
Inoue
T
T
Department of Ophthalmology, Osaka University Medical School, Suita, Osaka, Japan. tinoue@virus.kyoto-u.ac.jp
Inoue
Y
Y
Asari
S
S
Sunada
A
A
Inoue
Y
Y
Yamamoto
S
S
Nishida
K
K
Maeda
N
N
Watanabe
H
H
Shimomura
Y
Y
Tano
Y
Y
D000368:Aged; D000528:Alternaria / Q000187:drug effects* / Q000302:isolation & purification; D000935:Antifungal Agents / Q000627:therapeutic use*; D002963:Cladosporium / Q000187:drug effects* / Q000302:isolation & purification; D003315:Cornea / Q000382:microbiology; D004352:Drug Resistance, Microbial; D015821:Eye Infections, Fungal / Q000188:drug therapy* / Q000382:microbiology; D005670:Fusarium / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D007634:Keratitis / Q000188:drug therapy* / Q000382:microbiology; D015948:Keratoplasty, Penetrating; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology
D000935:Antifungal Agents