title: An intercomparison of IMRT delivery techniques: a case study for breast treatment.
abstract: Intensity-modulated radiotherapy beams can be delivered using a multileaf collimator by one of two methods: either by superposition of a series of multiple-static fields, or by moving the collimators while the beam is on to produce 'dynamically' modulated beams. The leaf trajectories in this dynamic mode are given by a series of linear steps between control points defining each collimator position at known intervals throughout an exposure. The complexity of the resulting modulation is limited in the first case by the number of fields superposed and in the second case by the number of control points defined. Results are presented for an experimental study that investigates the effect of changing both the number of fields for the multiple-static technique, and the number of control points for a dynamic 'close-in' technique. All deliveries studied are clinical intensity-modulated breast fields. The effect of using a universal wedge in conjunction with the multileaf collimator is also studied, together with a comparison of the relative efficiency, time taken and the absolute dosimetric accuracy of the various delivery options. It is shown that all delivery techniques produce equivalent dose distributions when using 15 control points, with 10 control points being sufficient to produce an adequate breast compensator distribution. Except for the case of a four-control-point dynamic delivery, the universal wedge makes no significant difference to the dose distribution. However, it makes the delivery less efficient. The close-in interpreter consistently produces deliveries that are more efficient than the more conventional sliding-window technique and faster than the multiple-static-field technique. Finally the close-in technique is compared to the more 'standard' leaf-sweep technique and shown to be equivalent.
authors.affiliation: Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Trust, Sutton, UK. m.partridge@physics.org
authors.forename: M
authors.initials: M
authors.lastname: Partridge
authors.forename: S
authors.initials: S
authors.lastname: Aldridge
authors.forename: E
authors.initials: E
authors.lastname: Donovan
authors.forename: P M
authors.initials: PM
authors.lastname: Evans
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D011874:Radiometry / Q000379:methods*; D020266:Radiotherapy, Conformal / Q000379:methods*