title: Endoscopic surgery for pineal region tumors.
abstract: Endoscopic surgery may play an important role in most patients with pineal region tumors. We report our experience with 5 patients treated by a burr hole endoscopic technique. The procedure included in all cases third ventriculostomy for the correction of hydrocephalus, CSF sample for cytology and tumor markers, and tumor biopsy for histological diagnosis. Endoscopic biopsies showed a pineocytoma in two cases, a germinoma in 2 and a low-grade astrocytoma in one. We agree that endoscopic surgery may allow us to select cases requiring a microsurgical approach (medium-sized or large non-germ-cell tumors) from cases to be treated only by irradiation and chemotherapy (germinomas and other non-germ-cell tumors). Then, in some patients with pineal region tumors the endoscopic procedure remains the only surgical treatment. When a direct microsurgical approach is indicated, it may be performed in a non-emergency situation and after correction of the hydrocephalus by endoscopic third ventriculostomy.
authors.affiliation: Department of Neurosurgery, University Federico II, Naples, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Gangemi
authors.forename: F
authors.initials: F
authors.lastname: Maiuri
authors.forename: G
authors.initials: G
authors.lastname: Colella
authors.forename: S
authors.initials: S
authors.lastname: Buonamassa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000473:pathology / Q000601:surgery*; D001706:Biopsy; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy / Q000379:methods*; D005260:Female; D018237:Germinoma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010870:Pineal Gland / Q000473:pathology / Q000601:surgery*; D010871:Pinealoma / Q000473:pathology / Q000601:surgery*; D020542:Third Ventricle / Q000473:pathology