[Seroepidemiology of adult diarrhea rotavirus in some countries of Asia].
OBJECTIVE
Adult diarrhea rotavirus (ADRV) is the major cause of severe adult diarrhea. This paper is to survey the ADRV antibody in sera of normal persons of some areas of Asia including China cities of Changchun, Nanking, Taiyuan, Wuhan, Kathmandu of Nepal, Seoul of South Korea and Hong Kong China.


METHODS
The ADRV antibody was detected by enzyme-linked immunosorbent blocking test.


RESULTS
The data of survey showed that 1. A total detection of 2183 normal sera from persons of Asian areas showed an ADRV antibody positive rate of 3.6% (79/2183); 2. In cities in China and in Hong Kong, the ADRV antibody showed a lower level in age groups of 10-20,20-30-; 3. The ADRV antibody was detectable in normal persons in 1997 in Hong Kong which indicated an earlier existence of ADRV there before the ADRV outbreak in mainland China in 1983; 4. The ADRV antibody level observed in 1986-1991 in Hong Kong showed no obvious difference; 5. ADRV antibody was detectable in normal persons in Nepal and South Korea.


CONCLUSIONS
The survey showed there was only a low level of ADRV antibody in normal persons in the Asian areas surveyed.
Wang
C
C
Institute of Virology, Chinese Academy of Preventive Medicine, Beijing 100052, China.
Shorttridge
K F
KF
Zhang
B
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D001208:Asia; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000821:virology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D012401:Rotavirus / Q000276:immunology*; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral