title: Intrahepatic biliary lesions after orthotopic liver transplantation.
abstract: Intrahepatic biliary lesions (IBL) are rare (2-9%) after orthotopic liver transplantation (OLT). The aim was to evaluate the incidence, etiology and outcome. In nine years, a total 532 OLTs were performed in 481 patients. Twenty-four patients developed IBL. Eight were due to HAT, seven to ABOI, three to CDR and six to PI. The time until diagnosis of HAT is longest in patients (14+/-6) with IBL. ABOI is another cause of IBL. CDR is a rare cause of IBL, however when it takes place, patients must undergo Rtx. Finally, PI is a relevant cause of IBL. In order to suppress the incidence of IBL we should consider 1) the systematic use of Doppler-Ultrasound; 2) emergency reoperation of patients with HAT, 3) avoid ABOI in OLT; 4) Rtx in cases of CDR, and 5) OLT should still be performed as an emergency procedure.
authors.affiliation: Liver Transplant Unit, Hospital Clinic, University of Barcelona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Rull
authors.forename: J C
authors.initials: JC
authors.lastname: Garcia Valdecasas
authors.forename: L
authors.initials: L
authors.lastname: Grande
authors.forename: J
authors.initials: J
authors.lastname: Fuster
authors.forename: A M
authors.initials: AM
authors.lastname: Lacy
authors.forename: F X
authors.initials: FX
authors.lastname: González
authors.forename: A
authors.initials: A
authors.lastname: Rimola
authors.forename: M
authors.initials: M
authors.lastname: Navasa
authors.forename: C
authors.initials: C
authors.lastname: Iglesias
authors.forename: J
authors.initials: J
authors.lastname: Visa
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D001649:Bile Duct Diseases / Q000209:etiology*; D001653:Bile Ducts, Intrahepatic / Q000098:blood supply / Q000293:injuries; D001787:Blood Group Incompatibility / Q000150:complications; D002908:Chronic Disease; D005260:Female; D006084:Graft Rejection / Q000150:complications; D006499:Hepatic Artery; D006801:Humans; D007511:Ischemia / Q000209:etiology; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation / Q000009:adverse effects; D013927:Thrombosis / Q000150:complications / Q000209:etiology
chemical_list: D000017:ABO Blood-Group System