Isolation of Clostridium innocuum from cases of recurrent diarrhea in patients with prior Clostridium difficile associated diarrhea.
Clostridium innocuum isolates resistant to vancomycin (MIC values of 16-24 microg/mL) were isolated from three patients with recurrent Clostridium difficile -associated diarrhea (CDAD). We discuss the clinical significance and problems associated with the identification and differentiation of these two clostridial species, which may result in misdiagnosis of patients.
Ackermann
G
G
Division of Infectious Diseases and Immunologic Diseases, Department of Internal Medicine, University of California-Davis, Medical Center, Sacramento, California, USA. grit.ackermann@ucdavis.edu
Tang
Y J
YJ
Jang
S S
SS
Silva
J
J
Rodloff
A C
AC
Cohen
S H
SH
D016360:Clostridioides difficile / Q000145:classification / Q000187:drug effects / Q000235:genetics; D003013:Clostridium / Q000145:classification* / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D003015:Clostridium Infections / Q000382:microbiology; D003967:Diarrhea / Q000382:microbiology*; D004761:Enterocolitis, Pseudomembranous / Q000382:microbiology*; D006801:Humans; D012329:RNA, Bacterial / Q000032:analysis; D012336:RNA, Ribosomal, 16S / Q000032:analysis; D012008:Recurrence
D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S