Novel sesquiterpenoids from the roots of Phyllanthus emblica.
Three novel bisabolane-type sesquiterpenoids, phyllaemblic acids B (1) and C (2) and phyllaemblicin D (3), together with two new phenolic glycosides, 2-carboxylmethylphenol 1-O-beta-D-glucopyranoside (4) and 2,6-dimethoxy-4-(2-hydroxyethyl)phenol 1-O-beta-D-glucopyranoside (5), were isolated from the roots of Phyllanthus emblica. The structures of 1-5 were established by spectral and chemical methods. The absolute stereochemistry of 1 and 2 was determined by applying the PGME method.
Zhang
Y J
YJ
Faculty of Pharmaceutical Sciences, Nagasaki University, Bunkyo-Machi 1-14, Nagasaki 852-8521, Japan.
Tanaka
T
T
Iwamoto
Y
Y
Yang
C R
CR
Kouno
I
I
D019665:Euphorbiaceae / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008516:Medicine, Chinese Traditional; D008968:Molecular Conformation; D015394:Molecular Structure; D008517:Phytotherapy; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013329:Structure-Activity Relationship
C435254:2,6-dimethoxy-4-(2-hydroxyethyl)phenol 1-O-glucopyranoside; C435253:2-carboxylmethylphenol 1-O-glucopyranoside; D005960:Glucosides; D012717:Sesquiterpenes; C435250:phyllaemblic acid B; C435251:phyllaemblic acid C; C435252:phyllaemblicin D