Cationic diazacrown ether for the separation of positional isomers by capillary electrophoresis.
The use of a positively charged diazacrown ether, N,N,N',N'-tetramethyl-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane dichloride (1), in capillary electrophoresis is reported, for the first time. The addition of the cationic diazacrown 1 to the running buffer permitted the successful separation of positional isomers of aromatic anions such as naphthalenedisulfonate, naphthalenedicarboxylate and phthalate. At a concentration of 1 of 2 mM, all the analyte anions were completely separated in less than 5 min. The ion association constants of the solute anions with diazacrown 1 were evaluated and the findings are discussed.
Mori
M
M
Division of Material Science, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo, Japan.
Tsue
H
H
Tanaka
S
S
D002412:Cations; D019075:Electrophoresis, Capillary / Q000379:methods*; D004988:Ethers, Cyclic / Q000737:chemistry*; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D013056:Spectrophotometry, Ultraviolet
D002412:Cations; D004988:Ethers, Cyclic