The Perivascular Cuff of Large Lymphoid Cells: A Clue to Diagnosis of Anaplastic Large Cell Lymphoma.
The small cell and lymphohistiocytic variants of anaplastic large cell lymphoma are commonly misdiagnosed as reactive lymphadenopathies. A helpful histologic clue is the presence of perivascular cuffs of large lymphoid cells, and the diagnosis can be readily confirmed by immunostaining for CD30 and ALK. Int J Surg Pathol 8(2):153-156, 2000
Chan
John K. C.
JK
Department of Pathology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong.