[The study on analgesic effect of local-release delivery system--Huangjiabang].
Laboratory investigation was made on analgesic effect of local release delivery system, Huangjiabang, which mainly includes Chinese medical herbs. Through the application of twisting-body and thermal-plate experiments on white rats. The result showed that the pain threshold was markedly elevated (P < 0.05, P < 0.001) after the rats were fed with Huangjiabang 125 mg/kg or 250 mg/kg body weight, and the number of twisting body's animals significantly decreased (P < 0.001). The analgestic mechanism of Huangjiabang delivery system relates to its effect of invigorating the circulation of blood and accelerating the stasis assimilation, remitting the inflammation.
Zhou
R
R
Stomatologic Faculty of Jiangxi Medical College, China.
Zhou
Z
Z
Yang
J
J
Lü
H
H
Huang
J
J
Chen
L
L
D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D051379:Mice; D008813:Mice, Inbred ICR; D017288:Pain Threshold / Q000187:drug effects*; D011897:Random Allocation
D018712:Analgesics, Non-Narcotic; D004365:Drugs, Chinese Herbal