[A comparative study on the blood vessel sclerosing effect of pingyungmycin and Natrii morrhuates].
Twelve adult rabbits were used in this experiment. After posterion auricular veins were temporarily blocked, pingyungmycin and natrii morrhuatis were injected separately and their effect on the blood vessels was studied. The results showed that pingyungmycin caused endotheliac cell oedema, degeneration, vascular shrinkage, vascular wall thickening, while the effect of natrii morrhuatis on the blood vessels was thrombosis, organization of thrombus and closure of the lumen of the blood vessels. The sclerosing mechanisms of the two medicines and their clinical applications were discussed.
Zhao
J
J
Stomatological College, Hubei Medical University, China..
Zhao
Y
Y
Chen
X
X
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology; D001761:Bleomycin / Q000031:analogs & derivatives / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000187:drug effects*; D011817:Rabbits; D012597:Sclerosing Solutions / Q000494:pharmacology*; D012976:Sodium Morrhuate / Q000494:pharmacology*
D000903:Antibiotics, Antineoplastic; D012597:Sclerosing Solutions; D001761:Bleomycin; C021771:zhengguangmycin; D012976:Sodium Morrhuate