Synthesis of steroidal glycosides bearing the disaccharide moiety of OSW-1 and their antitumor activities.
Nine glycosides bearing the disaccharide of OSW-1, namely 2-O-(4-methoxybenzoyl)-beta-D-xylopyranosyl-(1-->3)-2-O-acetyl-alpha-L-arabinopyranosides, were synthesized, and their antitumor activities were tested.
Ma
X
X
State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, 200032, Shanghai, China.
Yu
B
B
Hui
Y
Y
Miao
Z
Z
Ding
J
J
D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D002783:Cholestenones; D004187:Disaccharides / Q000737:chemistry*; D005960:Glucosides / Q000138:chemical synthesis*; D006031:Glycosylation; D012503:Saponins / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry*
D000970:Antineoplastic Agents; D002783:Cholestenones; D004187:Disaccharides; D005960:Glucosides; D012503:Saponins; D013256:Steroids; C106408:OSW 1