Regulation of clathrin-coated vesicle formation.
The formation of clathrin-coated pits at the plasma membrane requires the concerted action of many different molecules. The real challenge lies in determining the hierarchy of these interactions. We are using assays in both intact and permeabilized cells to dissect the temporal requirements for clathrin-coated vesicle formation, and also to examine the role of phosphorylation of the coat proteins.
Hill
E
E
Division of Molecular Cell Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.
Olusanya
O
O
van der Kaay
J
J
Downes
C P
CP
Andrews
P D
PD
Swedlow
J R
JR
Smythe
E
E
D033942:Adaptor Proteins, Vesicular Transport; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D022163:Clathrin-Coated Vesicles / Q000502:physiology*; D008565:Membrane Proteins / Q000378:metabolism*; D010766:Phosphorylation
D033942:Adaptor Proteins, Vesicular Transport; D002352:Carrier Proteins; D008565:Membrane Proteins; D000255:Adenosine Triphosphate