[Clinical significance of the determination of R-proteins in the ejaculate of patients with chronic prostatitis].
Products of cell receptor (R-proteins) catabolic lysis were measured in ejaculate of 121 patients with chronic prostatitis and 15 healthy males. R-protein levels were higher in the patients (U = 172.5; p = 0.047). When immunological indices of the ejaculate (IgA, sIgA, IgG, IgM, interleukin-8) were measured, it was found that in patients with chronic prostatitis there is a positive correlation between concentration of interleukin-8 and content of R-proteins (r = 0.43; p = 0.028). Positive correlation also exists between R-protein content and prostate volume (r = 0.24; p = 0.034) while negative one--between R-proteins concentration and size of the hypoechogenic sites in the prostate (r = -0.25; p = 0.039), between R-proteins in the ejaculate and serum level of fibrinogen B (r = -0.25; p = 0.021). It is inferred that elevation of ejaculate R-protein level occurs in alteration of the prostate. The test for R-proteins in ejaculate can be helpful in detection of early stages of chronic prostatitis.
Al'-Shukri
S Kh
SKh
Bobkov
Iu A
IuA
Gorbachev
A G
AG
Kozlov
V V
VV
Petlenko
S V
SV
Smirnov
V S
VS
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002908:Chronic Disease; D004542:Ejaculation; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D007136:Immunoglobulins / Q000032:analysis; D016209:Interleukin-8 / Q000032:analysis; D008297:Male; D008875:Middle Aged; D011472:Prostatitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000276:immunology; D011956:Receptors, Cell Surface / Q000032:analysis*; D014463:Ultrasonography
D007136:Immunoglobulins; D016209:Interleukin-8; D011956:Receptors, Cell Surface; D005340:Fibrinogen