[Principles of and criteria for sanitary standardization of antitumor cytostatics in the water of aqueous objects].
The list of sanitary standards with the mark "absent" should include antitumor cytostatics as the drugs satisfying the following criteria: extreme hazard and toxicity, late adverse effects, primarily mutagenic and carcinogenic properties; lack of highly sensitive methods for their determination in water; lack of 100%-efficiency methods for sewage purification. A complex of protective measures is justified and sanitary recommendations are given to protect the aqueous environment during cytostatic production.
Proínova
V A
VA
Rozhnov
G I
GI
Krasovskií
G N
GN
D000328:Adult; D000818:Animals; D000970:Antineoplastic Agents / Q000633:toxicity*; D015197:Carcinogenicity Tests; D004345:Drug Industry / Q000592:standards*; D005260:Female; D006801:Humans; D007220:Industrial Waste; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D009152:Mutagenicity Tests; D011247:Pregnancy; D051381:Rats; D011916:Rats, Inbred F344; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D000970:Antineoplastic Agents; D007220:Industrial Waste; D014874:Water Pollutants, Chemical