title: Convertases other than furin cleave beta-secretase to its mature form.
authors.affiliation: Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
authors.forename: I
authors.initials: I
authors.lastname: Pinnix
authors.forename: J E
authors.initials: JE
authors.lastname: Council
authors.forename: B
authors.initials: B
authors.lastname: Roseberry
authors.forename: L
authors.initials: L
authors.lastname: Onstead
authors.forename: W
authors.initials: W
authors.lastname: Mallender
authors.forename: J
authors.initials: J
authors.lastname: Sucic
authors.forename: K
authors.initials: K
authors.lastname: Sambamurti
mesh_terms: D000544:Alzheimer Disease / Q000201:enzymology; D053829:Amyloid Precursor Protein Secretases; D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000235:genetics / Q000378:metabolism*; D002460:Cell Line; D010450:Endopeptidases; D004792:Enzyme Precursors / Q000378:metabolism; D004795:Enzyme Stability; D045683:Furin; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D009154:Mutation; D011994:Recombinant Proteins / Q000378:metabolism; D012697:Serine Endopeptidases / Q000378:metabolism*; D013381:Subtilisins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D014162:Transfection
chemical_list: D004792:Enzyme Precursors; D011994:Recombinant Proteins; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D012697:Serine Endopeptidases; D013381:Subtilisins; D045683:Furin; D016282:Aspartic Acid Endopeptidases; C509284:BACE2 protein, human; C509280:BACE1 protein, human; C509282:Bace1 protein, mouse