[Clinical observation on nephrotic syndrome of lupus nephritis treated with integrated traditional Chinese and Western Medicine].
OBJECTIVE
To observe the clinical effect of integrated traditional Chinese and western medicine (TCM-WM) in treating nephrotic syndrome of lupus nephritis (NSLN).


METHODS
One hundred and fifty-five patients of NSLN were randomly divided into the TCM-WM group and the control group (treated with western medicine alone). Changes of activity index (AI) of lupus nephritis, urinary protein (UP), plasma albumin (PA), blood lipid (BL) of the patients before and after treatment were observed and compared. And the difference on recurrence rate and adverse reaction rate between the two groups were assessed.


RESULTS
The total effective rate of the TCM-WM group was 95%, significantly higher than that of the control group (79%, P < 0.05). The effect in improving AI, UP, PA and BL of the TCM-WM group was superior to that of the control group. The recurrence rate and adverse reaction rate of the former group were 8% and 34% respectively, which was much lower than those of the latter (38% and 68%, P < 0.05).


CONCLUSIONS
TCM-WM treatment is obviously superior to treatment with western medicine alone.
Wu
Q
Q
Department of Nephrology, Second People's Hospital of Fujian, Fuzhou 350000.
Ye
R
R
Wu
K
K
D000293:Adolescent; D000328:Adult; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008181:Lupus Nephritis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use*
D004365:Drugs, Chinese Herbal; D003520:Cyclophosphamide; D011241:Prednisone