Sialic acid synthase: the origin of fish type III antifreeze protein?
Fish type III antifreeze protein is homologous to the C-terminal region of mammalian sialic acid synthase. Similarity is greatest in the protein core and the flat ice-binding region. This relationship adds to the growing list of links between ice-binding proteins (antifreezes) and proteins that interact with sugars and polysaccharides.
Baardsnes
J
J
Dept of Biochemistry, Queen's University, ON, K7L 3N6, Kingston, Canada.
Davies
P L
PL
D000595:Amino Acid Sequence; D000818:Animals; D021343:Antifreeze Proteins, Type III / Q000737:chemistry*; D005399:Fishes; D008969:Molecular Sequence Data; D007652:Oxo-Acid-Lyases / Q000737:chemistry*; D011487:Protein Conformation; D017386:Sequence Homology, Amino Acid
D021343:Antifreeze Proteins, Type III; C018730:N-acetylneuraminate synthase; D007652:Oxo-Acid-Lyases