title: Head and neck squamous cell carcinoma in Hajjah, Yemen.
abstract: OBJECTIVE
  Incidence of head and neck squamous cell carcinoma seems to be relatively high in Yemen but not well documented. The purpose of this study is to analyze the clinical profile of the Yemeni patients of squamous cell carcinoma of the head and neck and to evaluate the possible relationship to kath chewing.
  
  
  METHODS
  With the help of a special protocol, all the patients of head and neck squamous cell carcinoma seen between October 1997 and December 1998 at the Ear, Nose and Throat and Dermatology Clinics of Saudi Hospital, Hajjah, Yemen Republic were subjected to detailed analysis. The diagnosis was confirmed by histopathologic studies in all the cases.
  
  
  RESULTS
  All the 36 patients (23 male and 13 female) were Yemani nationals, aged 18 to 80 years (median age 50 years). Thirty patients were Kath addicts. The tumor was localized to the oral cavity in 17 (47%) patients, oropharynx in 1 (3%) patient, nasopharynx in 15 (42%) patients and larynx in 3 (8%) patients.
  
  
  CONCLUSIONS
  The incidence of head and neck squamous cell carcinoma seems to be relatively high, especially the oral squamous cell carcinoma, all of whom had a habit of kath chewing, which may be considered as an important contributing factor.
authors.affiliation: Departments of E.N.T. and Dermatology, Saudi Hospital, Hajjah, Yemen Republic.
authors.forename: A H
authors.initials: AH
authors.lastname: Nasr
authors.forename: M L
authors.initials: ML
authors.lastname: Khatri
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced* / Q000453:epidemiology* / Q000473:pathology; D029754:Catha; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D005260:Female; D006258:Head and Neck Neoplasms / Q000139:chemically induced* / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000009:adverse effects*; D011159:Population Surveillance; D012307:Risk Factors; D017678:Sex Distribution; D019966:Substance-Related Disorders / Q000150:complications*; D014504:Urban Health / Q000706:statistics & numerical data*; D015006:Yemen / Q000453:epidemiology
chemical_list: D000697:Central Nervous System Stimulants; D010936:Plant Extracts