Memory impairment and cholinergic dysfunction by centrally administered Abeta and carboxyl-terminal fragment of Alzheimer's APP in mice.
Choi
S H
SH
Department of Pharmacology, College of Medicine, National Creative Research Initiative Centre for Alzheimer's Dementia and Neuroscience Research Institute, MRC, Seoul National University, Seoul 110-799, South Korea.
Park
C H
CH
Koo
J W
JW
Seo
J H
JH
Kim
H S
HS
Jeong
S J
SJ
Lee
J H
JH
Kim
S S
SS
Suh
Y H
YH
D000109:Acetylcholine / Q000032:analysis; D000544:Alzheimer Disease; D016229:Amyloid beta-Peptides / Q000008:administration & dosage*; D016564:Amyloid beta-Protein Precursor / Q000008:administration & dosage*; D000818:Animals; D002540:Cerebral Cortex / Q000737:chemistry / Q000648:ultrastructure; D002794:Choline / Q000502:physiology*; D003071:Cognition / Q000187:drug effects; D006624:Hippocampus / Q000737:chemistry / Q000648:ultrastructure; D007276:Injections, Intraventricular; D008568:Memory / Q000187:drug effects*; D051379:Mice; D008928:Mitochondria / Q000201:enzymology; D010446:Peptide Fragments / Q000008:administration & dosage*; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism
D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D010446:Peptide Fragments; D011768:Pyruvate Dehydrogenase Complex; D002794:Choline; D000109:Acetylcholine