Dielectro-deformations of erythrocyte: analysis of the ellipsoidal shear model.
Using the theoretical analysis within the framework of the proposed ellipsoidal shear electromechanical model of erythrocyte, the main mechanisms and relationships have been established and studied for the deformations of erythrocytes caused by a spatially homogeneous high-frequency electric field. The main types of the stress-strain curves characteristic of stationary and dynamic deformations caused by the rectangular-pulse and harmonic modulations of the field amplitude have been calculated. The relationship has been established between the parameters of essentially nonlinear stress-strain curves and mechanical, electric, and geometric parameters of erythrocyte. The impossibility of unlimited elongation of erythrocyte by the field, due to the conservation of the cell volume and surface area, has been shown, and the dependence of the maximum possible elongation of the cell on its volume has been calculated. It has been shown that the relaxation time of dynamic deformations of erythrocyte in the presence of an electric field considerably differs from that characteristic of the membrane material and sharply decreases with the increase of the initial elongation of the cell.
Kononenko
V L
VL
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow. konon@sky.chph.ras.ru
Ilyina
T A
TA
D002462:Cell Membrane / Q000378:metabolism*; D048429:Cell Size; D004574:Electromagnetic Fields; D004907:Erythrocyte Deformability / Q000502:physiology*; D004912:Erythrocytes / Q000378:metabolism*; D007700:Kinetics; D008433:Mathematics; D013314:Stress, Mechanical