[Experimental study of artificial bone composite with high biological induction in repairing bone defect].
On the basis of the animal model of segmental ultra defects in rabbits, two different composite artificial bones (HA-bBMP-Co and HA-Co) were first used to repair the segmental bone defect respectively in 12 rabbits. The results of X-ray, gross, stereomicroscopic and histological examination were found that HA-bBMP-Co was much faster and much better than HA-Co, involving induction of new bone formation in quality and quantity. It is suggested that there is a widespread prospect in use of HA-bBMP-Co as a bone substitute material.
Wang
D
D
Department of Oral and Maxillofacial Surgery, West China University of Medical Sciences.
Fei
W
W
Liu
S
S
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use*; D001861:Bone Regeneration; D018786:Bone Substitutes / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D008297:Male; D008863:Microspheres; D010012:Osteogenesis; D011817:Rabbits; D011897:Random Allocation; D014458:Ulna Fractures / Q000601:surgery*
D019485:Bone Morphogenetic Proteins; D018786:Bone Substitutes; D003094:Collagen; D017886:Durapatite