title: Laboratory stain removal and abrasion characteristics of a dentifrice based upon a novel silica technology.
abstract: These laboratory studies examined the stain removal efficacy and hard tissue abrasivity of a new dentifrice formulation--Crest Extra Whitening--based on the incorporation of elevated concentrations of a proprietary silica. Cleaning power assessments were made using a modification of the laboratory test method developed by Stookey and associates at Indiana University Oral Health Research Institute. Abrasion assessments were made using Radioactive Enamel and Radioactive Dentin Abrasivity (REA and RDA) measures. Results show that Crest Extra Whitening dentifrice produced statistically significantly improved stain removal when compared to a number of conventional dentifrices, including Crest Cavity Protection and Crest Tartar Protection, and a number of recently marketed cleaning and whitening dentifrices. Laboratory studies further demonstrated that the Crest Extra Whitening dentifrice produces dentin and enamel abrasivity similar to conventional silica dentifrices.
authors.affiliation: Procter & Gamble Company, Health Care Research Center, Mason, OH, USA.
authors.forename: D E
authors.initials: DE
authors.lastname: Rice
authors.forename: D J
authors.initials: DJ
authors.lastname: Dhabhar
authors.forename: D J
authors.initials: DJ
authors.lastname: White
mesh_terms: D000537:Aluminum Oxide / Q000627:therapeutic use; D000818:Animals; D001639:Bicarbonates / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000627:therapeutic use; D002417:Cattle; D002626:Chemistry, Pharmaceutical; D003116:Color; D003728:Dental Calculus / Q000628:therapy; D003741:Dental Deposits / Q000628:therapy; D003743:Dental Enamel / Q000648:ultrastructure*; D003802:Dentifrices / Q000737:chemistry / Q000627:therapeutic use*; D003804:Dentin / Q000648:ultrastructure*; D011756:Diphosphates / Q000627:therapeutic use; D010761:Phosphorus Radioisotopes; D019275:Radiopharmaceuticals; D012822:Silicon Dioxide / Q000737:chemistry / Q000627:therapeutic use*; D012969:Sodium Fluoride / Q000627:therapeutic use; D013499:Surface Properties; D013678:Technology, Pharmaceutical; D014073:Tooth Bleaching; D014075:Tooth Discoloration / Q000628:therapy*; D014099:Toothbrushing / Q000295:instrumentation
chemical_list: D001639:Bicarbonates; D002327:Cariostatic Agents; D003802:Dentifrices; D011756:Diphosphates; D010761:Phosphorus Radioisotopes; D019275:Radiopharmaceuticals; D012822:Silicon Dioxide; D012969:Sodium Fluoride; D000537:Aluminum Oxide