title: Nosocomial outbreak of influenza virus A (H3N2) infection in a solid organ transplant department.
abstract: BACKGROUND
  There is a strong body of evidence in favor of influenza virus immunization in solid organ recipients. However, little attention has been devoted to other reservoirs, such as the patients' relatives and, at the time of hospital admission, to the healthcare workers.
  
  
  METHODS
  Analysis of the epidemiology of an outbreak of nosocomial influenza A in a solid organ transplant unit.
  
  
  RESULTS
  Four cases of influenza A virus infection were reported during a short 4-day outbreak in a 12 single-room transplant unit. None of the patients had been immunized against influenza. Three patients had not been visited by their relatives between admission and influenza infection. Three nurses, among the 27 healthcare workers, presented with clinical flu symptoms at times consistent with nosocomial transmission.
  
  
  CONCLUSIONS
  Because the prevention of influenza infection by vaccination warrants a global strategy to target the different reservoirs, we suggest that the modern policy of vaccinating solid organ patients should be extended both to their relatives and to the healthcare workers of transplant units.
authors.affiliation: Department of Clinical Microbiology, CHU Toulouse-Rangueil, 1, Avenue Jean Poulhes, 31403 Toulouse Cedex 4, France. malavaud.s@chu-toulouse.fr.
authors.forename: S
authors.initials: S
authors.lastname: Malavaud
authors.forename: B
authors.initials: B
authors.lastname: Malavaud
authors.forename: K
authors.initials: K
authors.lastname: Sandres
authors.forename: D
authors.initials: D
authors.lastname: Durand
authors.forename: N
authors.initials: N
authors.lastname: Marty
authors.forename: J
authors.initials: J
authors.lastname: Icart
authors.forename: L
authors.initials: L
authors.lastname: Rostaing
mesh_terms: D000328:Adult; D003428:Cross Infection / Q000453:epidemiology*; D004196:Disease Outbreaks; D005260:Female; D005602:France; D006748:Hospital Departments; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus; D007251:Influenza, Human / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009726:Nurses; D016377:Organ Transplantation