title: Bone mineral content and bone mineral density in adolescent girls with anorexia nervosa--a longitudinal study.
abstract: OBJECTIVE
  Total body and lumbar spine bone mineral density (BMD-TB, BMD-L) and total body bone mineral content (BMC-TB) were measured to establish the course of bone demineralization in anorexia nervosa and the clinical factors influencing BMC-TB and BMD changes during treatment.
  
  
  METHODS
  Forty-two girls with DSM III-R anorexia nervosa, age 14.7+/-2.4 years. BMC-TB, BMD-TB and BMD-L were measured in approximately 7-month intervals for 27.8+/-4.1 months using DXA.
  
  
  RESULTS
  Despite nutritional improvement, there was an initial decrease of BMD-L, and no change in BMC-TB and BMD-TB. an increase in BMC-TB and BMD was observed after approx. 21 months from the beginning of the study.
  
  
  CONCLUSIONS
  The improvement in BMC-TB and BMD was related to changes in nutritional status and was significantly marked in younger patients, with earlier anorexia onset and before menarche.
authors.affiliation: Department of Child Psychiatry and Department of Internal Medicine and Nephrology, Medical University of Warsaw, Poland.
authors.forename: G
authors.initials: G
authors.lastname: Jagielska
authors.forename: T
authors.initials: T
authors.lastname: Wolańczyk
authors.forename: J
authors.initials: J
authors.lastname: Komender
authors.forename: C
authors.initials: C
authors.lastname: Tomaszewicz-Libudzic
authors.forename: J
authors.initials: J
authors.lastname: Przedlacki
authors.forename: K
authors.initials: K
authors.lastname: Ostrowski
mesh_terms: D000293:Adolescent; D000328:Adult; D000855:Anorexia / Q000150:complications*; D018488:Bone Demineralization, Pathologic / Q000209:etiology*; D015519:Bone Density; D002648:Child; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008159:Lumbar Vertebrae / Q000737:chemistry; D008572:Menarche; D009752:Nutritional Status