[Epiphyseolysis capitis femoris (ECF) in monozygotic twins].
OBJECTIVE
The frequency of bilateral slipped capital femoral epiphysis (SCFE) is 5-80%. A set of boy twins developed left-sided SCFE within 2 years. We tried to find a relationship between SCFE and HLA typing.


METHODS
We obtained the HLA typing and compared it to previously reported cases.


RESULTS
By comparing 14 gene loci we made sure that they are identical twins. In our patients as well as in may of previously reported cases of sets of boy twins HLA phenotype A2 were found, while in the sets of girl twins HLA phenotype A11 and B12 were found.


CONCLUSIONS
HLA phenotyping is needed in a larger number of SCFE twin cases to evaluate phenotypic patterns for coincidence to provide a basis for the genetic expression of this condition.
Siemon
B
B
Orthopädische Universitätsklinik Regensburg im Rheuma-Zentrum Bad Abbach. beate.siemon@klinik.uni-regensburg.de
Pfannenschmid
F
F
Jüsten
H P
HP
D000293:Adolescent; D001863:Bone Screws; D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D004200:Diseases in Twins / Q000235:genetics*; D004839:Epiphyses, Slipped / Q000000981:diagnostic imaging / Q000235:genetics* / Q000601:surgery; D005270:Femur Head / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D005500:Follow-Up Studies; D005799:Genes, Dominant / Q000235:genetics; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011859:Radiography; D014430:Twins, Monozygotic / Q000235:genetics