title: [Pseudoallergies].
abstract: Pseudo-allergic-reactions (PAR) are clinical manifestations including urticaria, angioedema, conjunctivitis, rhinitis, asthma, and anaphylaxis. The prevalence of PAR ranges from 0.1% to 75% according to various studies. The pathogenetic mechanism of these diseases is not immunologically mediated. Food, additives, and drugs are the main responsibilities for PAR. The diagnosis of PAR is characterized by the absence of specific IgE for the suspected products. The absence of immunological mechanisms is confirmed by in vitro and in vivo tests. The treatment of PAR is similar to that of allergic diseases (antihistamine drugs, steroids, B2 agonists, epinephrine).
authors.affiliation: Clinica Pediatrica III, Azienda Meyer, Centro di Allergologia e Broncopneumologia Pediatrica, Dipartimento di Pediatria, Università di Firenze, Via Luca Giordano, 13, 50132 Firenze, Italia.
authors.forename: R
authors.initials: R
authors.lastname: Bernardini
authors.forename: E
authors.initials: E
authors.lastname: Novembre
authors.forename: E
authors.initials: E
authors.lastname: Lombardi
authors.forename: M G
authors.initials: MG
authors.lastname: Monaco
authors.forename: M T
authors.initials: MT
authors.lastname: Monte
authors.forename: N
authors.initials: N
authors.lastname: Pucci
authors.forename: M E
authors.initials: ME
authors.lastname: Rossi
authors.forename: A
authors.initials: A
authors.lastname: Vierucci
mesh_terms: D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D015995:Prevalence