[Role of caudal pressor area of medulla oblongata in vasomotor tone of peripheral vessels].
To study the role of the caudal pressor area (CPA) on the ventral surface of medulla oblongata in vasotonia of the skeletal muscles and kidneys, perfusion pressures of vessels in skeletal muscles and kidneys were recorded to observe effects of microinjection of L-glutamate (L-glu) into CPA. The results are as follows. L-glu induced a significant increase of artery pressure (AP), perfusion pressure of muscles (PPm) and perfusion pressure of kidney (PPk), which was markedly attenuated by prior injection of phentolamine or propranolol to the bilateral pressor area. These results indicate that the vascular roles of CPA were mainly mediated via alpha- and/or beta-receptors.
Wang
J
J
Department of Physiology, Fujian Medical University, Fuzhou 350004.
Lin
M J
MJ
Jia
B J
BJ
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D002421:Caudate Nucleus / Q000502:physiology*; D007668:Kidney / Q000098:blood supply; D008297:Male; D008526:Medulla Oblongata / Q000502:physiology*; D018482:Muscle, Skeletal / Q000098:blood supply; D010646:Phentolamine / Q000494:pharmacology; D011311:Pressoreceptors / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D014666:Vasomotor System / Q000502:physiology*
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D011433:Propranolol; D010646:Phentolamine