Direct asymmetric aldol reactions of acetone using bimetallic zinc catalysts.
[reaction: see text] The enantioselective aldol reaction using a novel binuclear zinc catalyst of acetone with several aldehydes gave products in good yields (62-89%) with a high level of enantioselectivity (ee = 76-92%).
Trost
B M
BM
Department of Chemistry, Stanford University, Stanford, CA 94305-5080, USA. bmtrost@stanford.edu
Silcoff
E R
ER
Ito
H
H
D000096:Acetone / Q000737:chemistry*; D002384:Catalysis; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
D000096:Acetone; D015032:Zinc