Comparison of IgM, IgG1 and IgG2 responses to Trichinella spiralis and Trichinella britovi in swine.
Pigs infected with T. spiralis and T. britovi were followed by double (IgG) and triple antibody ELISA (IgG1, IgG2 and IgM) during a 12-week-period. Specific IgG and IgG1 responses were similar and showed a significant relation with the infecting doses and intensity of infection. Response to T. britovi was slightly lower than in groups infected with the same dose of T. spiralis. IgG2 response was weak and almost undetectable in the lowest infected pigs, but relationship with the intensity of infection was unclear. IgM antibodies showed rapid but transient increases, generally simultaneous to peaks of IgG response.
Serrano
F J
FJ
Unidad de Parasitología y Enfermedades Parasitarias, Departamento de Medicina y Sanidad Animal, Facultad de Veterinaria, Universidad de Extremadura, 10071 Cáceres, Spain. fserrano@unex.es
Pérez-Martin
J E
JE
Carrón
A
A
Navarrete
I
I
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D000917:Antibody Formation; D004797:Enzyme-Linked Immunosorbent Assay; D007074:Immunoglobulin G / Q000097:blood*; D007132:Immunoglobulin Isotypes / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood*; D007814:Larva / Q000276:immunology; D013552:Swine / Q000276:immunology*; D013553:Swine Diseases / Q000276:immunology* / Q000469:parasitology; D013997:Time Factors; D014234:Trichinella / Q000276:immunology*; D017160:Trichinella spiralis / Q000276:immunology*; D014235:Trichinellosis / Q000276:immunology / Q000662:veterinary*
D000909:Antibodies, Helminth; D007074:Immunoglobulin G; D007132:Immunoglobulin Isotypes; D007075:Immunoglobulin M