title: Volume-localized two-dimensional correlated magnetic resonance spectroscopy of human breast cancer.
abstract: A localized 2D correlation spectroscopic sequence (L-COSY) was implemented and applied in human breast cancer in vivo to evaluate the water to fat (both saturated and unsaturated) ratios and also to identify choline. Being in agreement with the conventional 1D magnetic resonance spectroscopy (MRS) results, elevated water to lipids ratios were found in breast cancers and choline was observed only in a few cancer patients.
authors.affiliation: Department of Radiological Sciences, University of California, Los Angeles, California 90095-1721, USA. athomas@mednet.ucla.edu
authors.forename: M A
authors.initials: MA
authors.lastname: Thomas
authors.forename: N
authors.initials: N
authors.lastname: Binesh
authors.forename: K
authors.initials: K
authors.lastname: Yue
authors.forename: N
authors.initials: N
authors.lastname: DeBruhl
mesh_terms: D000328:Adult; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008875:Middle Aged