title: Monoterpene glycosides and triterpene acids from Eriobotrya deflexa.
abstract: A phytochemical study on a methanolic extract of leaves of Eriobotrya deflexa led to the isolation and characterization of nine terpenoid compounds. Four of these are new chemical entities, including two monoterpene glycosides, (3S)-O-alpha-L-rhamnopyranosyl-(1-->3)-[4-O-(E)-coumaroyl]-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranosyl-linalool (1) and (3S)-O-alpha-L-rhamnopyranosyl-(1-->3)-[4-O-(Z)-coumaroyl]-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranosyl-linalool (2), and two triterpene acids, 1beta,2alpha,19alpha-trihydroxy-3-oxo-12-ursen-28-oic acid (3) and 2alpha,3alpha,19alpha-trihydroxy-12-oleanen-28-oic acid (4). Their structures were elucidated on the basis of spectroscopic analysis. The activities of these isolates in an in vitro antiproliferation test were also determined.
authors.affiliation: Institute of Botany, Academia Sinica, Nankang, Taipei, Taiwan.
authors.forename: T H
authors.initials: TH
authors.lastname: Lee
authors.forename: S S
authors.initials: SS
authors.lastname: Lee
authors.forename: Y C
authors.initials: YC
authors.lastname: Kuo
authors.forename: C H
authors.initials: CH
authors.lastname: Chou
mesh_terms: D000080462:Acyclic Monoterpenes; D000276:Adjuvants, Immunologic / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D006027:Glycosides / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007963:Leukocytes, Mononuclear / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D039821:Monoterpenes; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D013729:Terpenes / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C435249:1,2,19-trihydroxy-3-oxo-12-ursen-28-oic acid; C435248:2,3,19-trihydroxy-12-oleanen-28-oic acid; C435247:3-O-rhamnopyranosyl-(1-3)-(4-O-coumaroyl)-rhamnopyranosyl-(1-6)-glucopyranosyl-linalool; D000080462:Acyclic Monoterpenes; D000276:Adjuvants, Immunologic; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D039821:Monoterpenes; D013729:Terpenes; D014315:Triterpenes