title: Poisoning with Boophane disticha: a forensic case.
abstract: Scales from the bulb are traditionally used as wound dressing after circumcision and as general wound dressing. Concoctions of the bulb taken orally cause sedation, analgesia, visual hallucinations, irrational behaviour, coma or death. A man ingested 150 ml of a concoction to see who placed a spell on him. He started to hallucinate, thinking that somebody was attacking him. He pulled his gun and fired shots randomly, killing one person and injuring others. A gas chromatograph/mass spectrometer was used to analyze a sample of the concoction. The sample contained buphandrin, buphanine and crinamidine (alkaloids) and eugenol. Buphanine has a pharmacological action similar to that of hyoscine and, when ingested in toxic quantities, leads to excitement, agitation, hallucinations and coma. Eugenol is a volatile oil with analgesic properties. Although itcould not be proved that the concoction was only from Boophane disticha, the components were similar to those found in Amaryllidaceae to which Boophane belongs. The man's behaviour could be ascribed to the ingestion of compounds found in B. disticha.
authors.affiliation: Department of Pharmacology and Therapeutics, Medical University of Southern Africa, Pretoria.
authors.forename: W J
authors.initials: WJ
authors.lastname: du Plooy
authors.forename: L
authors.initials: L
authors.lastname: Swart
authors.forename: G W
authors.initials: GW
authors.lastname: van Huysteen
mesh_terms: D000284:Administration, Oral; D000328:Adult; D005554:Forensic Medicine; D008401:Gas Chromatography-Mass Spectrometry; D006212:Hallucinations / Q000139:chemically induced*; D006801:Humans; D019668:Liliaceae / Q000737:chemistry*; D008297:Male; D010936:Plant Extracts / Q000506:poisoning*; D010946:Plants, Medicinal / Q000506:poisoning*; D014754:Violence
chemical_list: D010936:Plant Extracts