Hair follicle nevus occurring in frontonasal dysplasia: an electron microscopic observation.
We report a rare hair follicle nevus that occurred in a three-month-old Japanese boy with mild frontonasal dysplasia. It had been present since birth. Histologically, numerous tiny vellus hair follicles were found within the dermis. The constituent cells of these follicles showed the features of follicular germ cells under the electron microscope. The fibroblasts around the follicles were active and merged with the colloid substance. Many myofibroblasts were found in a collagenous stroma in the atrophic lesion of the frontonasal dysplasia.
Kuwahara
H
H
Department of Plastic and Reconstructive Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
Lao
L M
LM
Kiyohara
T
T
Kumakiri
M
M
Igawa
H
H
D003937:Diagnosis, Differential; D005546:Forehead; D018859:Hair Follicle; D006801:Humans; D007223:Infant; D008297:Male; D009506:Nevus / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure; D009666:Nose; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure