[Effects of stimulation of dorsal medial area and ventral medial area of nucleus facialis on myoelectric activities of genioglossus and phrenic muscle].
Effects of electrical and chemical stimulation of the dorsal and ventral medial area of nucleus facialis (dMNF and vMNF) on myoelectric activities of genioglossus and phrenic muscle were observed in 44 urethane-anaesthetized and vagotomized rabbits. The results are as follows. (1) Long train electrical stimulation at the dMNF facilitated myoelectric activities of genioglossus and phrenic muscle. (2) Short train electrical stimulation of dMNF, when delivered in the inspiratory phase, caused prolongation of myoelectric activities of genioglossus and phrenic muscle; but when delivered in the expiratory phase, myoelectric activities of genioglossus and phrenic muscle were shortened. (3) Long train electrical stimulation at the vMNF inhibited myoelectric activities of genioglossus and phrenic muscle. (4) Short train electrical stimulation of vMNF caused shortening of myoelectric activities of genioglossus and phrenic muscle, when delivered in the inspiratory phase, but a prolongation when delivered in the expiratory phase. (5) The effects of microinjection of glutamate to dMNF and vMNF were similar to those of electrical stimulation. The above results suggest that both dMNF and vMNF participate in the regulation of the myoelectric activities of genioglossus and the upper airway resistance.
Wang
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L
Department of Physiology, College of Pre-Clinical Medicine, Shandong Medical University, Jinan 250012.
Liu
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L
Xu
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X
D000818:Animals; D003964:Diaphragm / Q000502:physiology; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D008297:Male; D020645:Mediodorsal Thalamic Nucleus / Q000502:physiology*; D010791:Phrenic Nerve / Q000502:physiology*; D011817:Rabbits; D012132:Respiratory Muscles / Q000502:physiology*; D014697:Ventromedial Hypothalamic Nucleus / Q000502:physiology*