Acute myopericarditis after diphtheria, tetanus, and polio vaccination.
We report the first case of myopericarditis after triple vaccination against diphtheria, tetanus, and poliovirus in a young adult. He presented with fever, acute chest pain, and diffuse ST-segment elevation 2 days after vaccination. Two-dimensional echocardiography findings were normal. Endomyocardial biopsy showed interstitial edema with diapedesis of erythrocytes. Laboratory findings showed inflammatory syndrome and elevated circulating immune complexes. He recovered within a few days with high-dose aspirin treatment and was without complications at 3-month follow-up. We discuss the different hypotheses for infective or hypersensitivity myocarditis.
Boccara
F
F
Service de Cardiologie, Saint Antoine University and Medical School, Paris, France.
Benhaiem-Sigaux
N
N
Cohen
A
A
D000208:Acute Disease; D000328:Adult; D022422:Diphtheria-Tetanus Vaccine / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D009205:Myocarditis / Q000175:diagnosis / Q000209:etiology*; D010493:Pericarditis / Q000175:diagnosis / Q000209:etiology*; D023321:Poliovirus Vaccines / Q000008:administration & dosage* / Q000009:adverse effects*; D014611:Vaccination
D022422:Diphtheria-Tetanus Vaccine; D023321:Poliovirus Vaccines