title: Effects of home environment, socioeconomic status, and health status on cognitive functioning in children with HIV-1 infection.
abstract: OBJECTIVE
  To investigate the effects of the home environment, socioeconomic status (SES), and health status on cognitive functioning in a sample of children with HIV-1 infection in a cross-sectional study.
  
  
  METHODS
  Forty-three caregivers and their children (2.5 to 12 years) participated. Caregivers completed two self-report measures of the home environment that included questions regarding the organization of the environment, play materials, parental involvement, variety of stimulation, and parental attitudes toward the provision of a cognitively stimulating environment. Cognitive functioning was assessed using a standardized intelligence (IQ) test. Children's medical charts were reviewed for HIV-1 classification status (CDC, 1994), CD4 cell counts, and current medication.
  
  
  RESULTS
  This study revealed two primary findings. First, measures of the home environment mediated the association between SES and child IQ. Second, measures of the home environment had a stronger association with child IQ during the advanced stages of disease than earlier stages of disease.
  
  
  CONCLUSIONS
  The home environment is associated with cognitive functioning among children with HIV-1 infection. Moreover, interventions aimed at enhancing the quality of the home environment may have a positive impact on these children's cognitive development.
authors.affiliation: Vanderbilt University, USA. coscj0@chmcc.org
authors.forename: J M
authors.initials: JM
authors.lastname: Coscia
authors.forename: B K
authors.initials: BK
authors.lastname: Christensen
authors.forename: R R
authors.initials: RR
authors.lastname: Henry
authors.forename: K
authors.initials: K
authors.lastname: Wallston
authors.forename: J
authors.initials: J
authors.lastname: Radcliffe
authors.forename: R
authors.initials: R
authors.lastname: Rutstein
mesh_terms: D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000151:congenital* / Q000453:epidemiology / Q000523:psychology; D015497:HIV-1; D006304:Health Status; D006801:Humans; D007360:Intelligence; D008297:Male; D011379:Prognosis; D012931:Social Environment; D012959:Socioeconomic Factors