Development of a cream from a self-emulsifying base and moisturizing actives.
This research study is based on the design and development of a semisolid emulsion system whose novel self-emulsifying base and preferentially moisturizing actives were investigated to find out whether the system mentioned could be used as a dermatological treatment for highly sensitive skins, including atopic ones. Thus, one of the main objectives of the present study consisted of in vivo evaluation of its effectiveness by means of non-invasive assessment techniques currently employed in cosmetology. Due to the fact that the new formula is, in principle, designed for skins that could present any kind of alteration, the current study was focused on rheological parameters of viscosity, thixotropy, and extensibility to guarantee not only an accurate assessment of composition but also a comfortable and safe application on skin.
Jiménez Soriano
M M
MM
Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Aclalá University, Alcalá de Henares, Madrid, Spain.
Fresno Contreras
M J
MJ
Sellés Flores
E
E
D003358:Cosmetics; D003879:Dermatologic Agents / Q000138:chemical synthesis*; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D009823:Ointment Bases / Q000737:chemistry*; D009824:Ointments / Q000737:chemistry*; D010784:Photomicrography; D013696:Temperature; D014783:Viscosity
D003358:Cosmetics; D003879:Dermatologic Agents; D009823:Ointment Bases; D009824:Ointments