Study of soluble adhesion molecules in some intestinal and tissue helminthes.
Soluble adhesion molecules namely soluble intercellular adhesion molecule-1 (sICAM-1) and soluble E-selectin (sELAM-1) were assayed in hydatid patients with or without complications. It was found that sICAM-1 was significantly increased in patients with hydatid cysts as compared to the control group. In lymphoedemic filariasis cases both sICAM-1 and sELAM-1 showed highly significant increase more than the control group. However, non of both soluble adhesion molecules were significantly elevated in patients with ascariasis, hymenolepiasis, heterophyiasis and strongyloidiasis as compared to controls. The results indicated that SICAM-1 & S ELAM-1 are useful markers for hydatidosis and filariasis, but not for ascariasis, hymenolepiasis, heterophyiasis and strongyloidiasis
El-Shazly
A M
AM
Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
Soliman
M
M
El-Kalla
M R
MR
Rezk
H
H
El Nemr
H E
HE
Handouusa
A E
AE
Helmy
M M
MM
D000328:Adult; D001196:Ascariasis / Q000097:blood; D015415:Biomarkers; D019040:E-Selectin / Q000097:blood*; D004443:Echinococcosis / Q000097:blood*; D005368:Filariasis / Q000097:blood*; D006801:Humans; D006925:Hymenolepiasis / Q000097:blood; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D013322:Strongyloidiasis / Q000097:blood
D015415:Biomarkers; D019040:E-Selectin; D018799:Intercellular Adhesion Molecule-1