title: Transcutaneous electrostimulation: emerging treatment for diabetic neuropathic pain.
abstract: Three independent studies utilizing transcutaneous electrical nerve stimulation to relieve diabetic peripheral neuropathic pain were reviewed. The proprietary equipment, an H-wave machine, administered all electrotherapy. The first two studies assessed the efficacy of electrotherapy alone and electrotherapy with amitriptyline. The treated electrotherapy group reported an overall greater reduction of symptoms, 52% with 2-3 weeks of active treatment. Amitriptyline alone produced a 26% reduction of pain after 4 weeks. The addition of active electrotherapy to amitriptyline produced a 66% reduction of pain. The final study looked at patients who have utilized electrotherapy for over one year. A reported 44% improvement of symptoms was attained with continuous electrotherapy treatment. The data also suggested that a maintenance treatment protocol for long-term pain relief would have to be developed.
authors.affiliation: California College of Podiatric Medicine, San Francisco, California, USA.
authors.forename: M
authors.initials: M
authors.lastname: Alvaro
authors.forename: D
authors.initials: D
authors.lastname: Kumar
authors.forename: I S
authors.initials: IS
authors.lastname: Julka
mesh_terms: D000639:Amitriptyline / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003929:Diabetic Neuropathies / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D009437:Neuralgia / Q000628:therapy*; D012189:Retrospective Studies; D012867:Skin / Q000294:innervation*; D004561:Transcutaneous Electric Nerve Stimulation
chemical_list: D000639:Amitriptyline