title: Self-rated quality of life measures: effect of change to a low-fat, high-fiber, fruit and vegetable enriched diet.
abstract: The Polyp Prevention Trial (PPT) was a multicenter, randomized clinical trial to determine the effect of a low-fat (20% of energy from fat), high-fiber (18 g/1,000 kcal/day), high-fruit/vegetable (3.5 servings/1,000 kcal/day) eatingplan on the recurrence of large bowel adenomatous polyps. The PPT provided an opportunity to examine the impact of dietary changes on quality of life. At baseline and annuallyfor 4 years, participants in the Quality of Life Substudy of PPT completed a Quality of Life Factors (QF) Questionnaire, a modified Block-National Cancer Institute Food Frequency Questionnaire, and a Health and Lifestyle Questionnaire. The 51-item QF Questionnaire assessed changes in nine domains: taste, convenience, cost, self-care, social, health assessment, health belief health action, and life satisfaction. The analysis compared annual changes in domain scores for intervention (n = 194) and control (n = 200) participants. At Year 1, 363 (92%) completed a questionnaire, and 325 (82%) participants completed a Year 4 questionnaire. There were no statistically significant differences between treatment groups in the change from baseline to Year 1 for the convenience, cost, taste, health assessment, and life satisfaction domains. At Year 1, intervention participants rated the self-care (p < .001), health belief (p = .021), and health action (p < .001) domains significantly higher and the social domain significantly lower (p <.001) than control participants. These changes were consistent through Years 2, 3, and 4. This study
authors.affiliation: National Cancer Institute, Bethesda, MD 20892-7354, USA.
authors.forename: D K
authors.initials: DK
authors.lastname: Corle
authors.forename: C
authors.initials: C
authors.lastname: Sharbaugh
authors.forename: D J
authors.initials: DJ
authors.lastname: Mateski
authors.forename: T
authors.initials: T
authors.lastname: Coyne
authors.forename: E D
authors.initials: ED
authors.lastname: Paskett
authors.forename: J
authors.initials: J
authors.lastname: Cahill
authors.forename: C
authors.initials: C
authors.lastname: Daston
authors.forename: E
authors.initials: E
authors.lastname: Lanza
authors.forename: A
authors.initials: A
authors.lastname: Schatzkin
mesh_terms: D018256:Adenomatous Polyps / Q000517:prevention & control*; D015992:Body Mass Index; D004032:Diet; D018752:Diet, Fat-Restricted; D004043:Dietary Fiber; D005247:Feeding Behavior; D005260:Female; D005500:Follow-Up Studies; D005527:Food, Fortified; D005638:Fruit; D015438:Health Behavior; D006801:Humans; D007414:Intestinal Neoplasms / Q000517:prevention & control*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012647:Self-Assessment; D012907:Smoking / Q000453:epidemiology; D011795:Surveys and Questionnaires; D014675:Vegetables