title: Effect of starvation and chloramphenicol on acceleration of bacterial dihexyl sulfosuccinate biotransformation.
abstract: Starvation for carbon and energy sources accelerated the biotransformation of the anion-active surfactant dihexyl sulfosuccinate (DHS) by Comamonas terrigena cells. Chloramphenicol (Cm) added at different time intervals to non-starved cells inhibited the DHS transformation. The largest difference between cells treated and non-treated by Cm was observed for a 16-h-starvation period. Protein synthesis de novo during starvation enhanced the DHS biotransformation efficiency. A partial transformation of DHS in the presence of Cm indicated the constitutive character of enzymes involved in primary DHS biodegradation.
authors.affiliation: Institute of Microbiology, Slovak Academy of Sciences, 814 34 Bratislava, Slovakia.
authors.forename: Z
authors.initials: Z
authors.lastname: Chmelárová
authors.forename: I
authors.initials: I
authors.lastname: Závadská
authors.forename: J
authors.initials: J
authors.lastname: Húska
authors.forename: D
authors.initials: D
authors.lastname: Tóth
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis; D001711:Biotransformation / Q000187:drug effects; D002701:Chloramphenicol / Q000494:pharmacology*; D020585:Comamonas / Q000187:drug effects* / Q000378:metabolism*; D003470:Culture Media; D007700:Kinetics; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology; D013386:Succinates / Q000378:metabolism*; D013501:Surface-Active Agents / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; D011500:Protein Synthesis Inhibitors; D013386:Succinates; D013501:Surface-Active Agents; D014874:Water Pollutants, Chemical; C110836:di-n-hexyl sulfosuccinate; D002701:Chloramphenicol