title: Facile synthesis of rotaxanes through condensation reactions of DCC-[2]rotaxanes.
abstract: [reaction: see text] In this Letter, we present an easy method for the synthesis of rotaxanes using a novel DCC-[2]rotaxane. The DCC-[2]rotaxane is composed of dibenzo-24-crown-8 ether, an amino acid tether, and di-tert-butyl phenyl rings as blocking groups. It is relatively stable and can be purified by column chromatography. A series of model rotaxanes were obtained in good yields by condensing the DCC-[2]rotaxanes with N-(2-aminoethyl)-3,5-di-tert-butylbenzylamide in acetonitrile and chloroform.
authors.affiliation: Department of Chemistry, University of Cincinnati, Ohio 45221-0172, USA.
authors.forename: D W
authors.initials: DW
authors.lastname: Zehnder
authors.forename: D B
authors.initials: DB
authors.lastname: Smithrud