Five-year mortality in men and women with atrial fibrillation.
OBJECTIVE
Five-year mortality in men and women with atrial fibrillation (AF).


METHODS
A follow-up of the medical records of patients with AF registered on September 30, 1993.


METHODS
One community health centre in Stockholm County.


METHODS
129 patients (76 men and 53 women).


METHODS
Observed and expected, age- and sex-standardised, 5-year mortality rates. Significant risk factors by multiple logistic regression.


RESULTS
Women had a higher mean age (77.5 vs 72.8 years) and more often suffered from heart failure and hypothyreosis. Five-year mortality rate for men was 30% vs expected 27% in Sweden and 24% in the community; for women it was 43% vs expected 29% (p <0.05) and 23% in the community (p < 0.001), i.e. an excess mortality of 49% and 88%, respectively. Significant factors predicting death by logistic regression among women were: age (odds ratio 1.39, p < 0.001), levothyroxine treatment (odds ratio 27.87, p < 0.05) and diabetes (odds ratio 20.75, p < 0.05).


CONCLUSIONS
AF is related to an excess sex- and age-standardised, 5-year mortality in women but not in men, with levothyroxine treatment as one significant factor.
Wändell
P E
PE
The Husläkarna i Osteråker Health Centre, Akersberga, Sweden.
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000401:mortality*; D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008485:Medical Audit; D008875:Middle Aged; D012737:Sex Factors; D013548:Sweden / Q000453:epidemiology; D014859:Warfarin / Q000627:therapeutic use
D000925:Anticoagulants; D014859:Warfarin