Pedophilia is accompanied by increased plasma concentrations of catecholamines, in particular epinephrine.
Plasma epinephrine and norepinephrine concentrations were measured in pedophiles and normal men both in placebo conditions and after administration of meta-chlorophenylpiperazine (mCPP), a post-synaptic 5-HT2 receptor agonist. The plasma concentrations of catecholamines, in particular epinephrine, were significantly increased in pedophiles. It is concluded that pedophiles may have an increased activity of the sympathoadrenal system.
Maes
M
M
Department of Psychiatry and Neuropsychology, University Hospital of, Maastricht, Maastricht, The Netherlands. crc-mh@online.be
De Vos
N
N
Van Hunsel
F
F
Van West
D
D
Westenberg
H
H
Cosyns
P
P
Neels
H
H
D000328:Adult; D002395:Catecholamines / Q000097:blood* / Q000378:metabolism; D004837:Epinephrine / Q000097:blood* / Q000378:metabolism; D006801:Humans; D008297:Male; D010378:Pedophilia / Q000097:blood*; D010879:Piperazines / Q000494:pharmacology; D011985:Receptors, Serotonin / Q000187:drug effects; D017366:Serotonin Receptor Agonists / Q000494:pharmacology
D002395:Catecholamines; D010879:Piperazines; D011985:Receptors, Serotonin; D017366:Serotonin Receptor Agonists; C015068:1-(3-chlorophenyl)piperazine; D004837:Epinephrine