title: Dowling-Degos disease--a heat aggravated variant.
abstract: A 22-year-old woman presented with a 5-year history of a micropapular eruption localized to the flexor aspect of her limbs as well as persistent reticulate pigmentation of her neck and upper chest resembling Darier's disease. The eruption was associated with pruritus that was precipitated by heat and was worse in summer. The axillae, groins and inframammary areas had multiple papules but lacked reticulate pigmentation. Multiple biopsies showed an epidermis with club- and antler-like rete ridges but no acantholysis or dyskeratosis. This distinct clinical presentation may represent an unusual heat aggravated variant of Dowling-Degos disease that clinically shares features with Darier's disease and transient acantholytic dermatosis.
authors.affiliation: Skin and Cancer Foundation Australia, Sydney, New South Wales, Australia. skossard@scfa.edu.au
authors.forename: S
authors.initials: S
authors.lastname: Kossard
authors.forename: J
authors.initials: J
authors.lastname: Krivanek
mesh_terms: D000328:Adult; D001132:Arm; D001365:Axilla; D003937:Diagnosis, Differential; D005260:Female; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D009333:Neck; D010859:Pigmentation Disorders / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology