title: Allergic reactions to decorative skin paintings.
abstract: BACKGROUND
  Dye mixtures containing henna, P-phenylenediamine (PPD), and indigo are applied to the skin in various parts of the world for religious purposes, social recognition or fun.
  
  
  OBJECTIVE
  To identify eventual allergens responsible for contact sensitization to skin decoration in three young children. Lesions remained strictly limited to the site painted during the summer holiday. None of the children had a previous history of contact dermatitis, but two of them suffered from severe seasonal allergic rhinoconjunctivitis.
  
  
  RESULTS
  Patch testing revealed severe contact hypersensitivity to PPD in all three patients, and one child presented a positive prick test to 1% henna in water. The eruptions resolved following spontaneous elimination of the dyes and topical applications of corticosteroids, but left residual depigmentation.
  
  
  CONCLUSIONS
  PPD is the main allergen identified in allergic reactions to decorative skin paintings.
authors.affiliation: Department of Dermatopathology, University Medical Center of Liège, Belgium. af.nikkels@chu.ulg.ac.be
authors.forename: A F
authors.initials: AF
authors.lastname: Nikkels
authors.forename: F
authors.initials: F
authors.lastname: Henry
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D000293:Adolescent; D002648:Child; D004396:Coloring Agents / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007203:Indigo Carmine; D007211:Indoles / Q000009:adverse effects; D010328:Patch Tests; D010655:Phenylenediamines / Q000009:adverse effects; D018570:Risk Assessment; D013653:Tattooing / Q000009:adverse effects*
chemical_list: D004396:Coloring Agents; D007211:Indoles; D010655:Phenylenediamines; D007203:Indigo Carmine; C029728:4-phenylenediamine