title: Fast three-dimensional sodium imaging of human brain.
abstract: A three-dimensional sodium imaging technique with a minimum echo time of 0.9 ms is described in a 2.0 Tesla whole-body system. The relaxation behaviour in vivo of sodium was analysed: a fast T(2)(*) relaxation component between 1.2 and 1.6 ms and a slow T(2)(*) relaxation component between 7.1 ms and 8.4 ms were quantified in brain tissue of three volunteers. Three-dimensional sodium images of the human brain were acquired in 8.5 min with a resolution of 4.7 x 4.7 x 10 mm (0.2 cc voxel size) and a signal-to-noise ratio of 20 in brain tissue and 30 in cerebrospinal fluid.
authors.affiliation: Lehrstuhl für Experimentelle Physik V, Physikalisches Institut, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany. sakoehler@physik.uni-wuerzburg.de
authors.forename: S
authors.initials: S
authors.lastname: Köhler
authors.forename: C
authors.initials: C
authors.lastname: Preibisch
authors.forename: M
authors.initials: M
authors.lastname: Nittka
authors.forename: A
authors.initials: A
authors.lastname: Haase
mesh_terms: D001703:Biophysics / Q000379:methods*; D001921:Brain / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012964:Sodium; D013997:Time Factors
chemical_list: D012964:Sodium