Genetic diversity of Pneumocystis carinii isolated from human immunodeficiency virus-positive patients in Turin, Italy.
By DNA sequence analysis we identified two new strain types and five novel sporadic variations among 25 isolates of Pneumocystis carinii f. sp. hominis obtained from 19 human immunodeficiency virus-positive patients. Of these, 13 were infected with a single strain and 6 were coinfected. Fifteen different combination types were identified among the 18 strains for which complete molecular typing was accomplished.
Volpe
G
G
Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.
Sbaiz
L
L
Avanzini
C
C
Caramello
P
P
Savoia
D
D
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D005800:Genes, Fungal; D020459:Genes, rRNA / Q000235:genetics; D014644:Genetic Variation / Q000235:genetics*; D006801:Humans; D007558:Italy; D016533:Mycological Typing Techniques; D011010:Pneumocystis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D011020:Pneumonia, Pneumocystis / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA