title: A rare case of advanced ovarian carcinoma who developed difficulty walking 25 days after treatment with weekly paclitaxel.
abstract: Although taxol has shown significant activity in advanced ovarian cancer, peripheral neuropathy is likely to become the major dose-limiting toxicity. We describe a case of advanced ovarian carcinoma who developed difficulty walking because of marked pain in the lower extremities and loss of proprioception 25 days after treatment with weekly taxol (80 mg/m(2)x3).
authors.affiliation: Department of Obstetrics and Gynecology, National Defense Medical College, Namiki 3-2, Tokorozawa, Saitama 359-8513, Japan. QWL04765@nifty.ne.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: H
authors.initials: H
authors.lastname: Hiramatsu
authors.forename: H
authors.initials: H
authors.lastname: Seto
authors.forename: T
authors.initials: T
authors.lastname: Kita
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D002277:Carcinoma / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007866:Leg; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D017239:Paclitaxel / Q000009:adverse effects*; D010146:Pain / Q000139:chemically induced; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*; D011434:Proprioception / Q000187:drug effects*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel