[Analysis of etiological agents and death-relating factors of pulmonary infections in immunocompromised patients].
OBJECTIVE
To explore the distribution of etiological agents and death-relating factors of pulmonary infections in immunocompromised hosts(ICH).


METHODS
80 patients of pulmonary infections in ICH confirmed by etiological and(or) pathological diagnosis were retrospectively analyzed.


RESULTS
The distribution of etiological agents of pulmonary infections (except for cytomegalovirus, CMV): common bacteria 56%, mycobacterium tuberculosis 29%, fungus 11%, pneumocystis carinii 4%. Mortality of pulmonary infections in ICH showed significant difference between age 67% (> or = 60 years): 48% (< 60 years), bacteremia 86% (yes): 45% (no), white blood cell count 67%, 87% (> 10 x 10(9)/L, < 4.0 x 10(9)/L): 23% (4.0-10) x 10(9)/L, extent of lesions in x-ray film 65% (diffuse): 23% (local) (P < 0.05, P < 0.01), however, there was no obvious difference in sex, underlying diseases, types of etiological agents, mixed infections.


CONCLUSIONS
Bacteria was one of the most common etiological agents of pulmonary infections in ICH, the latent reactivation and relapse of pulmonary tuberculosis in ICH should be emphasized sufficiently. The preliminary analysis of death-relating factors showed: age, bacteremia, white blood cell count, extent of lesions in x-ray film were related to the prognosis of pulmonary infections in ICH.
Qu
J
J
Department of Pulmonary Medicine, Zhongshan Hospital, Institute of Respiratory Diseases, Shanghai Medical University, Shanghai 200032.
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L
Li
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D000328:Adult; D000368:Aged; D002423:Cause of Death; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation; D008180:Lupus Erythematosus, Systemic / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D018410:Pneumonia, Bacterial / Q000209:etiology*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000209:etiology*