title: [Coronary surgery of the beating heart. First year of experience in a series of 317 non-selected coronary patients].
abstract: From May 1999 to May 2000, 317 unselected patients, representing 92.7% of all coronary artery surgery procedures, underwent open heart surgery of the beating heart by median sternotomy with the aid of a cardiac stabilising device. The main preoperative characteristics were: mean age = 66.1 years; men = 78.9%; left main stem disease = 31.8%; mean left ventricular ejection fraction = 54.1%; mean Parsonnet index = 16.9. These 317 patients were compared with a group of 303 patients who underwent coronary bypass surgery the year before by the same surgical team with cardiopulmonary bypass (CPB) and cardiac standstill. Seven hundred and eighty-six distal anastomoses were carried out in the beating heart group (2.48 grafts per patient) compared with 2.91 in the CPB group: p < 0.001). There were 10.1% single bypass, 37.5% double bypass, 47.3% triple bypass and 5% quadruple bypass procedures. A cardiopulmonary bypass was required in 13 patients (4.1%). The mortality at 30 days was 3.1% versus 4.6% in the CPB group (p = NS). The need for blood transfusion was reduced by nearly 40% in the beating heart group (23.7% versus 39.9%, p < 0.001). The incidence of cerebrovascular complications was reduced from 3% in the CPB group to 0.6% in the beating heart group (p = 0.06). The peak postoperative troponine I levels were much lower in the beating heart group (2.5 versus 6.4 ng/ml, p < 0.001). The authors conclude that surgery on the beating heart is feasible in most patients. Compared with conventional surgery under CPB, there seems to be less requirement for blood transfusion and a tendency to reduce the cerebral risk. Nevertheless, a large prospective randomised trial is required to validate the potential advantages and limitations of this technique with respect to conventional surgery and to determine the optimal indications of surgery on the beating heart.
authors.affiliation: Département de chirurgie cardiovasculaire et de cardiologie, hôpital européen de Paris, La Roseraie, 93308 Aubervilliers.
authors.forename: J P
authors.initials: JP
authors.lastname: Saal
authors.forename: D
authors.initials: D
authors.lastname: Le Houerou
authors.forename: G
authors.initials: G
authors.lastname: Ghorayeb
authors.forename: C
authors.initials: C
authors.lastname: Benkelfat
authors.forename: C
authors.initials: C
authors.lastname: Cloix
authors.forename: P
authors.initials: P
authors.lastname: Jessen
authors.forename: E
authors.initials: E
authors.lastname: Palsky
authors.forename: F
authors.initials: F
authors.lastname: Pouillart
authors.forename: D
authors.initials: D
authors.lastname: Guilmet
authors.forename: M
authors.initials: M
authors.lastname: Romano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001803:Blood Transfusion; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000517:prevention & control; D001026:Coronary Artery Bypass / Q000379:methods*; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D013249:Sternum / Q000601:surgery; D016896:Treatment Outcome