title: The impact of improved safety on maintaining a sufficient blood supply.
abstract: The impact of improved safety on maintaining a sufficient blood supply is becoming an increasingly real issue facing the National Blood Service in England and North Wales. This paper shows the extent of the impact that safety measures can have on reducing collection levels, without making any value judgement on the safety critera themselves. It demonstrates that underlying trends in collection are making it increasingly difficult to meet demand. Further potential restrictions, perhaps associated with variant Creutzfeldt-Jacob disease (vCJD), will require a reassessment of the safety-sufficiency trade-off. The analysis strongly suggests that continual enhancement of safety criteria, for both individual donor and patient benefit, will lead to insufficient supply to meet current levels of hospital demand. New approaches are needed to effectively manage blood throughout the supply chain, thereby ensuring sufficient supply.
authors.affiliation: National Blood Service, Reeds Crescent, Watford, UK. liz.reynolds@nbs.nhs.uk
authors.forename: E
authors.initials: E
authors.lastname: Reynolds
authors.forename: C
authors.initials: C
authors.lastname: Wickenden
authors.forename: A
authors.initials: A
authors.lastname: Oliver
mesh_terms: D001771:Blood Banks / Q000706:statistics & numerical data / Q000639:trends*; D001782:Blood Donors / Q000523:psychology / Q000706:statistics & numerical data / Q000600:supply & distribution*; D001803:Blood Transfusion / Q000592:standards* / Q000706:statistics & numerical data; D007562:Creutzfeldt-Jakob Syndrome / Q000097:blood / Q000517:prevention & control* / Q000635:transmission; D004739:England; D006801:Humans; D009042:Motivation; D011785:Quality Assurance, Health Care; D012449:Safety; D065227:Transfusion Reaction; D014852:Wales