title: [Synapse architectonics of the cerebral cortex in the evolutionary aspect].
abstract: The formation of synapses in ontogenesis is an important problem of neuromorphology. The paper shows that the bulk of synapses of the developing brain is formed on the basis of previous specialization of membranes. Early in ontogenesis, most formed synapses shows asymmetric contacts. In postnatal ontogenesis, the formation of synapses proceeds due to the simultaneous occurrence of specialization of membranes and synaptic vesicles, by forming a "dot" active zone. Systemogenesis, such as the general law of brain development, plays an important role in understanding the functional significance of the shown mechanisms of maturation of synapses.
authors.forename: N N
authors.initials: NN
authors.lastname: Bogolepov
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000033:anatomy & histology* / Q000196:embryology / Q000254:growth & development* / Q000648:ultrastructure; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000196:embryology / Q000254:growth & development / Q000648:ultrastructure; D005865:Gestational Age; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000033:anatomy & histology / Q000196:embryology / Q000254:growth & development / Q000648:ultrastructure; D051381:Rats; D012154:Reticular Formation / Q000033:anatomy & histology / Q000196:embryology / Q000254:growth & development / Q000648:ultrastructure; D013003:Somatosensory Cortex / Q000033:anatomy & histology / Q000196:embryology / Q000254:growth & development / Q000648:ultrastructure; D013569:Synapses / Q000648:ultrastructure*