Pattern of expression of the tetraspanin Tspan-5 during brain development in the mouse.
Here, we report the pattern of expression of the tetraspanin mTspan-5 at various developmental stages. Expression was first seen at E10 and remained until adulthood, with increased levels between P0 and P5. mTspan-5 showed high expression in the cortical areas and Purkinje cells throughout development. Moreover, transcripts were also detected in the developing heart, forelimbs, and hindlimbs.
García-Frigola
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C
Department of Cell Biology, Faculty of Biology, University of Barcelona, Av. Diagonal 645, 1st Floor, E-08020, Barcelona, Spain.
Burgaya
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F
de Lecea
L
L
Soriano
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E
D000818:Animals; D001921:Brain / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D002531:Cerebellum / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D015870:Gene Expression; D020869:Gene Expression Profiling; D017403:In Situ Hybridization; D008565:Membrane Proteins / Q000235:genetics*; D051379:Mice; D016548:Prosencephalon / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D059470:Tetraspanins
D008565:Membrane Proteins; D012333:RNA, Messenger; D059470:Tetraspanins; C435756:Tspan5 protein, mouse