title: [Detection of IgG antibody to hepatitis G virus by ELISA].
abstract: OBJECTIVE
  To study the relation of HGV IgG antibody (anti- HGV IgG) to various viral infections, ALT and HGV RNA.
  
  
  METHODS
  To detect anti-HGV IgG from 315 persons infected with various viruses hepatitis (A - E) and 117 healthy blood donors by ELISA. The detection of ALT of these peoples, and detect HGV RNA of the samples of positive anti-HGV IgG by RT-PCR were also carried out.
  
  
  RESULTS
  The positive rate of anti-HGV IgG of 117 blood donors was 3.42% (4/117), and that of the people infected by non A- E, HAV, HBV, HCV, HEV, HBV and HCV, HBV and HDV, HBV and HEV were 5.95%(5/84), 0(0/3), 3.75% (3/80), 17. 28%(14/81), 0(0/15), 33.33%(5/15), 3.33%(1/30), 16.66%(1/6), respectively. The relativity of anti-HGV IgG and HGV RNA was 30.30% (10/33), and 33.33% of ALT level in the antibody positive samples were elevated.
  
  
  CONCLUSIONS
  HGV may infect people alone, or coinfect with HBV or /and HCV, but is highly relative to HCV, and the coinfection of HGV with HCV may increase the degree of liver damage.
authors.affiliation: Guangdong Provincial People' s Hospital, Guangzhou 510080, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhen
authors.forename: M
authors.initials: M
authors.lastname: Liang
authors.forename: J
authors.initials: J
authors.lastname: Wang
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay; D029407:GB virus C / Q000235:genetics / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006525:Hepatitis, Viral, Human / Q000276:immunology / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D012367:RNA, Viral / Q000097:blood
chemical_list: D006508:Hepatitis Antibodies; D007074:Immunoglobulin G; D012367:RNA, Viral; D000410:Alanine Transaminase