Reproductive outcome after laparoscopic instillation of hyperosmolar glucose into unruptured tubal pregnancies.
OBJECTIVE
To determine intrauterine and ectopic pregnancy rates after local instillation of 50% glucose into unruptured tubal pregnancies.


METHODS
Retrospective cohort of 183 patients, who were observed for 16 to 108 months (median, 64 months).


METHODS
University hospital.


METHODS
One hundred eighty-three women who underwent laparoscopic instillation of hyperosmolar glucose for unruptured tubal pregnancies.


METHODS
Completion of questionnaires.


METHODS
Pregnancy rate, tubal recurrence rate.


RESULTS
A total of 124 women returned the questionnaire and had a desire for spontaneous conception. The conception rate and the intrauterine pregnancy rate were 79% and 73%, respectively. Seventy percent of all women with desire for spontaneous conception had live births. The rate of subsequent ectopic pregnancies was 12%. Tubal patency of the treated tube was demonstrated in 69% of 39 women at hysterosalpingography.


CONCLUSIONS
The long-term prognosis for conception after laparoscopic instillation of hyperosmolar glucose for unruptured tubal pregnancy is favorable and comparable to that of other conservative treatments.
Giuliani
A
A
Department of Obstetrics and Gynecology, University of Graz, Graz, Austria. giuliani@kfunigraz.ac.at
Hoenigl
W
W
Schoell
W
W
Tamussino
K
K
Arikan
G
G
Lang
P F
PF
D000328:Adult; D015331:Cohort Studies; D005260:Female; D005950:Glucose Solution, Hypertonic / Q000627:therapeutic use*; D006801:Humans; D010535:Laparoscopy; D017063:Outcome Assessment, Health Care; D011247:Pregnancy; D018873:Pregnancy Rate; D011274:Pregnancy, Tubal / Q000628:therapy*; D011379:Prognosis; D012189:Retrospective Studies; D011795:Surveys and Questionnaires
D005950:Glucose Solution, Hypertonic