[The effect of calcium ion in perilymphatic fluid on guinea pig's distortion product otoacoustic emissions].
OBJECTIVE
To study the mechanism of the production of distortion product otoacoustic emissions (DPOAE) by electromobility of out hair cell.


METHODS
The changes of nine gninea pig's DPOAE by means of perfusion of artificial perilymphatic fluid with and without calcium ion were observed.


RESULTS
The mean value of DPOAE decreased from 41.3 dB to 13.7 dB after perfusion of fluid devoid of calcium ion, it revived to 36.7 dB after reperfusion with normal perilymphatic fluid. The result supports Pickle's muscle theory for DPOAE's mobile mechanism and does not support Brownell's electromobility theory.


CONCLUSIONS
A normal concentration of calcium ion in perilymphatic fluid is necessary for outer hair cell to produce DPOAE.
Li
K
K
Shanghai First People's Hospital, Shanghai 200080.
Wang
Z
Z
Cao
K
K
D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000502:physiology*; D005260:Female; D006168:Guinea Pigs; D018072:Hair Cells, Auditory, Outer / Q000502:physiology*; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology; D010498:Perilymph / Q000378:metabolism*
D002118:Calcium