Expression of preprotachykinin-B, the gene that encodes neurokinin B, in the rat uterus.
Neurokinin B, a peptide belonging to the tachykinin family, is undetectable in peripheral tissues from nonpregnant animals. In the present study, we analysed the expression of the preprotachykinin-B (PPT-B) gene, which encodes neurokinin B, in the rat uterus. Preprotachykinin-B mRNA was expressed in the uterus and its levels varied greatly depending upon the hormonal conditions. This is consistent with a role of this tachykinin in the regulation of uterine functions.
Pinto
F M
FM
Centro de Investigaciones Científicas Isla de La Cartuja, Instituto de Investigaciones Químicas, Avda. Americo Vespucio s/n, 41092, Sevilla, Spain.
Cintado
C G
CG
Devillier
P
P
Candenas
M L
ML
D000818:Animals; D005260:Female; D015870:Gene Expression; D066298:In Vitro Techniques; D015287:Neurokinin B / Q000235:genetics*; D011498:Protein Precursors / Q000235:genetics*; D012333:RNA, Messenger / Q000096:biosynthesis; D051381:Rats; D015320:Tachykinins / Q000235:genetics*; D014599:Uterus / Q000502:physiology*
D011498:Protein Precursors; D012333:RNA, Messenger; D015320:Tachykinins; C044206:preprotachykinin; D015287:Neurokinin B