title: Papular acantholytic dyskeratosis of the vulva.
abstract: We describe two patients with unusual asymptomatic, papular lesions on the vulva, clinically resembling lichen planus, the histology of which revealed unexpected findings of suprabasilar clefting, acantholysis and dyskeratotic cells giving rise to corps ronds and grains together with hyperkeratosis and parakeratosis, features originally associated with a diagnosis of Darier's disease. Focal acantholytic dyskeratosis has been described in a wide variety of inflammatory and neoplastic processes including those involving mucous membranes and has been attributed various diagnostic labels. We feel that the findings in our patients are consistent with a diagnosis of papular acantholytic dyskeratosis of the vulva, a rare condition, which was first described in 1984.
authors.affiliation: Department of Dermatology, Royal Liverpool University Hospital, UK. fam.shaw@virgin.net
authors.forename: H K
authors.initials: HK
authors.lastname: Bell
authors.forename: C W
authors.initials: CW
authors.lastname: Farrar
authors.forename: R K
authors.initials: RK
authors.lastname: Curley
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011539:Pruritus Vulvae / Q000175:diagnosis; D017444:Skin Diseases, Papulosquamous / Q000175:diagnosis* / Q000473:pathology; D014845:Vulvar Diseases / Q000175:diagnosis* / Q000473:pathology