[Relationship between Syndrome-Type in TCM and four trace urinary proteins in patients with bronchial asthma].
OBJECTIVE
To explore the possible relationship between Syndrome-Type in TCM and the 4 trace urinary proteins in patients with bronchial asthma.


METHODS
The 4 kinds of trace urinary proteins in 217 patients with asthma were measured by radioimmunoassay, and that in 66 normal subjects were compared.


RESULTS
The results showed that there were increments of urinary albumin, urinary IgG, urinary beta 2-microglobulin and urinary Tamm-Horsfall protein in patients with asthma; and the gradual increase tended to be accompanied by the continuous aggravation of patient's condition on TCM Syndrome-Type. Furthermore, these datas proved that the 4 trace urinary proteins might be the most sensitive indicators for detecting impaired renal functions than serum blood urea nitrogen and creatinine.


CONCLUSIONS
There were the objective material foundations on TCM Syndrome-Type in asthmatics, which consisted of renal glomerular dysfunctions to filter out albumin and IgG, renal tubular dysfunction to reabsorb beta 2-microglobulin, and to synthesize and excrete Tamm-Horsfall protein.
Chen
A
A
PLA 458th Hospital, Guangzhou 510602.
Zhao
S
S
Huang
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000652:urine*; D001249:Asthma / Q000175:diagnosis / Q000652:urine*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000652:urine*; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D009088:Mucoproteins / Q000652:urine; D058949:Uromodulin; D001613:beta 2-Microglobulin / Q000652:urine
D007074:Immunoglobulin G; D009088:Mucoproteins; C548612:UMOD protein, human; D058949:Uromodulin; D001613:beta 2-Microglobulin