Elaboration of HPLC method for biotin determination in multiple vitamin drugs and comparison with microbiological method.
We were searching for optimal analytical conditions for the biotin determination by the HPLC method with detection at the wavelength 200 nm in multiple vitamin drugs. Statistical parameters of the HPLC method and the microbiological method of the biotin determination, were compared.
Kłaczkow
G
G
Department of Vitamin Drugs, Drug Institute, Warsaw, Poland.
Czyz
E
E
Anuszewska
E L
EL
D001710:Biotin / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D008828:Microbiological Techniques; D014815:Vitamins / Q000032:analysis*
D014815:Vitamins; D001710:Biotin