Changes in biochemical parameters of bone turnover and bone mineral density in post-pregnancy osteoporosis.
A lactating 32-year-old woman in whom severe back pain developed 5 months after delivery is described. Cross-linked carboxyterminal telopeptide of type I collagen and pyridinoline, which are parameters of bone resorption, was markedly elevated with low bone mineral density. A high level of bone resorption was associated with post-pregnancy osteoporosis.
Honjo
S
S
Department of Obstetrics and Gynecology, Gunma University School of Medicine, 472-6 Kami-Shinden-machi, Maebashi, Gunma, 371-0821, Japan.
Mizunuma
H
H
D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D000596:Amino Acids / Q000097:blood; D015415:Biomarkers / Q000097:blood*; D015519:Bone Density; D016723:Bone Remodeling; D001862:Bone Resorption / Q000150:complications; D003094:Collagen / Q000097:blood; D024042:Collagen Type I; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D015675:Osteocalcin / Q000097:blood; D010024:Osteoporosis / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D010446:Peptide Fragments / Q000097:blood; D010455:Peptides / Q000097:blood; D011347:Procollagen / Q000097:blood; D011644:Puerperal Disorders / Q000175:diagnosis*
D000596:Amino Acids; D015415:Biomarkers; D024042:Collagen Type I; D007527:Isoenzymes; D010446:Peptide Fragments; D010455:Peptides; D011347:Procollagen; C052929:collagen type I trimeric cross-linked peptide; C042813:procollagen type I carboxy terminal peptide; D015675:Osteocalcin; C015484:pyridinoline; C036020:deoxypyridinoline; D003094:Collagen; D000469:Alkaline Phosphatase