HeartMate III: pump design for a centrifugal LVAD with a magnetically levitated rotor.
A long-term, compact left ventricular assist device (LVAD), the HeartMate III, has been designed and fabricated, featuring a centrifugal pump with a magnetically levitated rotor. The pump has been optimized by in vitro testing to achieve a design point of 7 L/min against 135 mm Hg at high hydrodynamic efficiency (30%) and to be capable of up to 10 L/min under such a load. Furthermore, the pump has demonstrated no mechanical failures, low hemolysis (4-10 mg/dl plasma free Hb), and low thrombogenicity during six (40, 27, 59, 42, 27, and 49-day) in vivo bovine studies.
Bourque
K
K
Thoratec Corp, Woburn, Massachusetts 01888-2697, USA.
Gernes
D B
DB
Loree
H M
HM
Richardson
J S
JS
Poirier
V L
VL
Barletta
N
N
Fleischli
A
A
Foiera
G
G
Gempp
T M
TM
Schoeb
R
R
Litwak
K N
KN
Akimoto
T
T
Watach
M J
MJ
Litwak
P
P
D000818:Animals; D002417:Cattle; D006353:Heart-Assist Devices; D008280:Magnetics; D011474:Prosthesis Design; D011673:Pulsatile Flow