Prevention of Alzheimer's disease.
Delaying the emergence of Alzheimer's disease (AD) symptoms by 5 to 10 years would have a significant public health impact in the long term. Data generated from large scale epidemiological studies on risk as well as protective factors for AD are leading to treatment strategies that can be tested in transgenic animal models as well as human populations at higher genetic risk.
Gauthier
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McGill Centre for Studies in Aging, 6825 Boul. LaSalle, Verdun, Québec, Canada H4H 1R3.
D000368:Aged; D000544:Alzheimer Disease / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D004195:Disease Models, Animal; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants