title: Use of dynamic light scattering and Scheimpflug imaging for the early detection of cataracts.
abstract: Cataract is a leading cause of blindness. Diabetes and glycemic conditions enhance the chances of developing cataracts early. At clinical stage cataracts are detected and documented by slit-lamp biomicroscopy and Scheimpflug photography. A compact fiber optic probe, developed for space experiments, was mounted on a Scheimpflug imaging system. The probe detects and documents cataracts at pre-clinical stage noninvasively and quantitatively. The early detection at the molecular level may lead to medical treatment of cataracts, better control of glycemia, and diabetes mellitus.
authors.affiliation: NASA Glenn Research Center, National Center for Microgravity Research in Fluids and Combustion Science, Cleveland, Ohio, USA. rafat.r.ansari@grc.nasa.gov
authors.forename: R R
authors.initials: RR
authors.lastname: Ansari
authors.forename: M B
authors.initials: MB
authors.lastname: Datiles
mesh_terms: D000818:Animals; D002386:Cataract / Q000175:diagnosis* / Q000209:etiology; D002417:Cattle; D003925:Diabetic Angiopathies / Q000150:complications / Q000175:diagnosis*; D004867:Equipment Design; D005123:Eye; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007834:Lasers; D007908:Lens, Crystalline / Q000033:anatomy & histology / Q000502:physiology*; D008027:Light; D008853:Microscopy / Q000295:instrumentation / Q000379:methods; D023421:Models, Animal; D010781:Photography / Q000295:instrumentation* / Q000379:methods*; D012542:Scattering, Radiation