title: C18orf2, a novel, highly conserved intronless gene within intron 5 of the GNAL gene on chromosome 18p11.
abstract: We have characterized a novel intronless human gene (C18orf2) which is embedded in intron 5 of the G-protein gene (GNAL) on chromosome 18p11. This gene codes for a 199 amino acid polypeptide with a predicted molecular weight of 22.1 kDa. It is highly homologous to a number of predicted developmental proteins in organisms ranging from yeasts to Drosophila. C18orf2 mRNA was found to be expressed in various tissues.
authors.affiliation: Collagen Research Unit, Biocenter Oulu and Department of Medical Biochemistry, Aapistie 7, 90220 Oulu, Finland.
authors.forename: J T
authors.initials: JT
authors.lastname: Vuoristo
authors.forename: W H
authors.initials: WH
authors.lastname: Berrettini
authors.forename: L
authors.initials: L
authors.lastname: Ala-Kokko
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002887:Chromosomes, Human, Pair 18 / Q000235:genetics*; D003001:Cloning, Molecular; D017124:Conserved Sequence / Q000235:genetics*; D020224:Expressed Sequence Tags; D044385:GTP-Binding Protein alpha Subunits; D020869:Gene Expression Profiling; D020962:Heterotrimeric GTP-Binding Proteins / Q000235:genetics*; D006801:Humans; D007438:Introns / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics*; D020161:Physical Chromosome Mapping; D016133:Polymerase Chain Reaction; D011401:Promoter Regions, Genetic / Q000235:genetics; D011506:Proteins / Q000737:chemistry / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics; D016415:Sequence Alignment; D012984:Software
chemical_list: D044385:GTP-Binding Protein alpha Subunits; D011506:Proteins; D012333:RNA, Messenger; C084618:olfactory G protein subunit alpha olf; D020962:Heterotrimeric GTP-Binding Proteins