Two episodes of life-threatening anaphylaxis in the same patient to a chlorhexidine-sulphadiazine-coated central venous catheter.
Chlorhexidine allergy has been described in the literature, mainly in Japanese individuals. Most reactions have been limited to the skin, mild in severity and a result of chlorhexidine containing solutions such as 'Savlon' (Novartis Consumer Health, Horesham, UK). We describe what we believe is the first reported case of anaphylaxis in a European patient to a chlorhexidine- sulphadiazine-coated central venous catheter.
Stephens
R
R
UCL Hospitals, The Middlesex Hospital, Mortimer Street, London W1N 8AA, UK.
Mythen
M
M
Kallis
P
P
Davies
D W
DW
Egner
W
W
Rickards
A
A
D000707:Anaphylaxis / Q000139:chemically induced*; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002405:Catheterization, Central Venous / Q000295:instrumentation*; D002710:Chlorhexidine / Q000009:adverse effects*; D004338:Drug Combinations; D006801:Humans; D008297:Male; D008875:Middle Aged; D013411:Sulfadiazine / Q000009:adverse effects*
D000890:Anti-Infective Agents; D004338:Drug Combinations; D013411:Sulfadiazine; D002710:Chlorhexidine