Characterization of the safety, effectiveness and use of oral sodium phosphate.
OBJECTIVE
The objective of this study was to assess the tolerability, safety and effectiveness of an oral sodium phosphate solution as a colon preparation method prior to colonoscopy, compared to a standard polyethylene glycol preparation.


METHODS
A cohort-based multicenter, prospective, observational clinical study was conducted.


METHODS
Twenty-nine centers from all over Spain participated in this study, including a total of 638 patients who met all the inclusion criteria established.


RESULTS
The oral sodium phosphate solution has an effectiveness and safety profile similar to the standard poliethylene glycol preparation; however, due to its dosage, it is better tolerated by patients, with a statistically significant difference between both preparations.


CONCLUSIONS
Based on the effectiveness, safety and tolerability profile of oral sodium phosphate solution in patients, it can be considered the preparation of choice before colonoscopy, since it allows a fast, effective and safe bowel cleansing in patients without contraindications.
Pou Fernández
J M
JM
Endoscopy Department, Hospital General de Catalunya, Barcelona, Spain.
Rodríguez Muñoz
S
S
Sala Felis
T
T
D000284:Administration, Oral; D002400:Cathartics / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage*; D011446:Prospective Studies
D002400:Cathartics; D010710:Phosphates; C018279:sodium phosphate