Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid.
The symbiotic nitrogen-fixing soil bacterium Sinorhizobium meliloti contains three replicons: pSymA, pSymB, and the chromosome. We report here the complete 1,354,226-nt sequence of pSymA. In addition to a large fraction of the genes known to be specifically involved in symbiosis, pSymA contains genes likely to be involved in nitrogen and carbon metabolism, transport, stress, and resistance responses, and other functions that give S. meliloti an advantage in its specialized niche.
Barnett
M J
MJ
Department of Biological Sciences, and Howard Hughes Medical Institute, Stanford University, CA 94305, USA.
Fisher
R F
RF
Jones
T
T
Komp
C
C
Abola
A P
AP
Barloy-Hubler
F
F
Bowser
L
L
Capela
D
D
Galibert
F
F
Gouzy
J
J
Gurjal
M
M
Hong
A
A
Huizar
L
L
Hyman
R W
RW
Kahn
D
D
Kahn
M L
ML
Kalman
S
S
Keating
D H
DH
Palm
C
C
Peck
M C
MC
Surzycki
R
R
Wells
D H
DH
Yeh
K C
KC
Davis
R W
RW
Federspiel
N A
NA
Long
S R
SR
D016960:Agrobacterium tumefaciens / Q000235:genetics; D000596:Amino Acids / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000235:genetics; D002352:Carrier Proteins / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D005057:Eukaryotic Cells / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial / Q000235:genetics; D015723:Gene Library; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D009584:Nitrogen / Q000378:metabolism; D009586:Nitrogen Fixation / Q000235:genetics; D010641:Phenotype; D010957:Plasmids / Q000235:genetics*; D012093:Replicon / Q000235:genetics; D017422:Sequence Analysis, DNA; D016962:Sinorhizobium meliloti / Q000235:genetics*; D013045:Species Specificity; D014158:Transcription, Genetic / Q000235:genetics
D000596:Amino Acids; D002135:Calcium-Binding Proteins; D002352:Carrier Proteins; D004269:DNA, Bacterial; D009584:Nitrogen