title: Synthetic utility of stannyl enolates as radical alkylating agents.
abstract: [reaction: see text] The radical-initiated beta-ketoalkylation of haloalkanes with tributylstannyl enolates is described. Stannyl enolates derived from aromatic ketones are reactive toward the homolytic beta-ketoalkylation of simple haloalkanes as well as those activated by an electron-withdrawing group. The reactivity of stannyl enolates as radical alkylating agents can be utilized for an efficient three-component coupling reaction among stannyl enolates, haloalkanes, and electron-deficient alkenes.
authors.affiliation: Department of Chemistry, Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8571, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Miura
authors.forename: N
authors.initials: N
authors.lastname: Fujisawa
authors.forename: H
authors.initials: H
authors.lastname: Saito
authors.forename: D
authors.initials: D
authors.lastname: Wang
authors.forename: A
authors.initials: A
authors.lastname: Hosomi