[The effects of hepatitis G virus infection on clinical features and liver pathologic lesions of chronic hepatitis C].
OBJECTIVE
To explore the clinical and pathological effect of hepatitis G virus infection on chronic hepatitis C.


METHODS
Detecting HGV-RNA by reverse transcription-polymerase chain reaction from serum samples of 53 chronic hepatitis C through patients as diagnosed by liver biopsy. The clinical and pathologic features of the patients with positive HGV-RNA were compared with those of patients with negative HGV-RNA.


RESULTS
The results showed that 15 patients (28.3%) were positive for serum HGV-RNA and there were no significant differences in clinical manifestations, biochemical indexes, HCV-RNA positive rates and the liver pathologic lesions between these HGY RNA positive and negative groups (P > 0.05).


CONCLUSIONS
These data indicate that HGV coinfection does not affect the liver lesions and HCV replication of chronic hepatitis C.
Shang
Q
Q
The 88th Hospital of Chinese PLA, Taiwan 271000, China.
Zhang
G
G
Yu
J
J
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D018178:Flaviviridae Infections / Q000097:blood / Q000150:complications*; D029407:GB virus C / Q000235:genetics; D019698:Hepatitis C, Chronic / Q000150:complications / Q000473:pathology*; D006525:Hepatitis, Viral, Human / Q000097:blood / Q000150:complications*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008297:Male; D012367:RNA, Viral / Q000097:blood
D012367:RNA, Viral