title: Acute endogenous endophthalmitis due to Bartonella henselae.
abstract: A 45-year-old man presented with progressively worsening vitreitis of 1 week's duration. Treatment for cat-scratch disease 3 years prior to presentation and persistent vitreitis led to vitrectomy, and analysis of the vitrectomy specimen revealed inflammatory cells and necrotic debris; polymerase-chain-reaction analysis of the vitreous fluid sample, done by use of a novel heminested protocol, demonstrated the presence of Bartonella henselae DNA. Treatment with doxycycline led to improvement in the intraocular inflammation but resulted in a poor visual outcome.
authors.affiliation: Department of Ophthalmology, University of Illinois at Chicago, Chicago, IL, USA. debrgold@uic.edu
authors.forename: D A
authors.initials: DA
authors.lastname: Goldstein
authors.forename: L
authors.initials: L
authors.lastname: Mouritsen
authors.forename: S
authors.initials: S
authors.lastname: Friedlander
authors.forename: H H
authors.initials: HH
authors.lastname: Tessler
authors.forename: D P
authors.initials: DP
authors.lastname: Edward
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018416:Bartonella henselae / Q000235:genetics / Q000302:isolation & purification*; D002372:Cat-Scratch Disease / Q000175:diagnosis* / Q000188:drug therapy; D004269:DNA, Bacterial / Q000302:isolation & purification; D003937:Diagnosis, Differential; D004318:Doxycycline / Q000627:therapeutic use; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004318:Doxycycline