[Electrochemical detoxication of the lymph in the treatment of patients with suppurative-resorptive endotoxicosis].
A new method for lymph detoxication in patients with pyoresorptive endotoxicosis is proposed. The method is based on electrochemical oxidation of the lymph, is simple and cheap. After 4-h exposure of the lymph with 0.04% sodium hypochlorite the concentration of the main toxic metabolites appreciably decreased, while the levels of total protein and leukocytes changed negligibly. Electrochemical detoxication of the lymph was used in the treatment of 13 patients with pyoresorptive endotoxicosis and led to improvement of the clinical status and rapid decrease in the levels of the major toxic metabolites, which was particularly expressed 3 days after the treatment. No negative effects were observed. Hence, electrochemical detoxication of the lymph appreciably improved the results of treatment of patients with cholestatic endotoxicosis.
Fedoseev
A V
AV
Tarasenko
S V
SV
Zaĭtsev
O V
OV
D001798:Blood Proteins / Q000378:metabolism; D002779:Cholestasis / Q000628:therapy; D004202:Disinfectants / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D004563:Electrochemistry; D004731:Endotoxins; D006801:Humans; D008196:Lymph / Q000166:cytology / Q000187:drug effects; D018655:Lymphocyte Count; D010084:Oxidation-Reduction; D012973:Sodium Hypochlorite / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016060:Sorption Detoxification; D013492:Suppuration; D013997:Time Factors
D001798:Blood Proteins; D004202:Disinfectants; D004731:Endotoxins; D012973:Sodium Hypochlorite