[Clinical and experimental study on using Cassia angustifolia extract as enema after abdominal operation].
OBJECTIVE
To investigate the curative effect and mechanism of using Cassia angustifolia extract (CAE) in treating gastrointestinal tract dysfunction after abdominal operations.


METHODS
Enema administration of CAE (Clyster method) was used.


RESULTS
The result of 130 patients was very effective in reducing the rate of gastrointestinal decompression, accelerating the restitution of borborygmi and the time of exhaustion. Animal experiment showed the CAE function is very obvious in enhancing the bowel movement of rats (P < 0.05). It can enhance peristalsis and contraction amplitude of vibration in the isolated ileum of rats (P < 0.05). It can push on the charcoal powder in intestinal tract of mice obviously (P < 0.05).


CONCLUSIONS
CAE could regulate disordered function of gastrointestinal tract after abdominal operations.
Wang
M
M
Qingdao Hospital of Integrated Traditional Chinese and Western Medicine, Shandong 266002.
Yan
S
S
Wang
J
J
D000006:Abdomen, Acute / Q000601:surgery*; D000285:Administration, Rectal; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002366:Cassia / Q000627:therapeutic use*; D002648:Child; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D005767:Gastrointestinal Diseases / Q000601:surgery; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008875:Middle Aged; D008517:Phytotherapy; D018515:Plant Leaves / Q000627:therapeutic use; D010946:Plants, Medicinal; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal