title: [Diagnostic value of needle biopsy and frozen section histological examination in the surgery of primary parotid tumors].
abstract: The necessity of fine-needle aspiration biopsy (FNAB) in the diagnosis and treatment of parotid gland lesions is still controversial. We examined the accuracy of cytology and histology in a review of 128 parotid gland tumors who underwent surgery with FNAB, n = 102 and/or frozen section examination (FS), n = 94. The diagnostic sensibility and specificity for malignant or benign lesions was respectively 81.5% and 97.5% for FNAB and 75% and 100% for FS as compared with definite histology (110 tumors were benign and 18 malignant). Insufficient material for FNAB evaluation was found in 12 patients mainly with small tumors (p = 0.043) or with tumors located in the deep process of the parotid gland (p = 0.029). Surgery was inappropriate (superficial lobe resection for malignant tumor) because of 4 false negative FS diagnoses. FNAB offers valuable information in the diagnosis of nonsurgical lesions and permits to avoid FS if FNAB identify a benign lesion. FS remains mandatory if FNAB evaluation is not possible or suggests a neoplastic tumor.
authors.affiliation: CHU Bichat Claude Bernard, Service ORL, 46 rue Henri Huchard, F-75877 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Longuet
authors.forename: E
authors.initials: E
authors.lastname: Nallet
authors.forename: C
authors.initials: C
authors.lastname: Guedon
authors.forename: J
authors.initials: J
authors.lastname: Depondt
authors.forename: P
authors.initials: P
authors.lastname: Gehanno
authors.forename: B
authors.initials: B
authors.lastname: Barry
mesh_terms: D001707:Biopsy, Needle / Q000379:methods* / Q000592:standards; D005188:False Negative Reactions; D005260:Female; D006652:Histological Techniques / Q000379:methods* / Q000592:standards; D006801:Humans; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric