title: [Prevention of hemoglobinopathies in Brussels: a necessity?].
abstract: Haemoglobinopathies are the most frequent genetic diseases in the world. The estimated frequency of carriers in the world is of 200 millions while there is about 300.000 births per year of major forms of haemoglobinopathies. The neonatal screening of haemoglobinopathies performed at the Hospital Erasme on around 80% of births in Brussels since 1994 has demonstrated that the frequency of carriers of an abnormal haemoglobin is around 1.5% while more than 1/2.000 newborns has a major haemoglobinopathy. A strategy must be adopted to manage the haemoglobinopathies in Brussels.
authors.affiliation: Service de Chimie Médicale, Hôpital Erasme, U.L.B.
authors.forename: B
authors.initials: B
authors.lastname: Gulbis
authors.forename: F
authors.initials: F
authors.lastname: Cotton
authors.forename: V
authors.initials: V
authors.lastname: Hansen
authors.forename: A
authors.initials: A
authors.lastname: Ferster
authors.forename: M
authors.initials: M
authors.lastname: Toppet
authors.forename: P
authors.initials: P
authors.lastname: Cochaux
authors.forename: J
authors.initials: J
authors.lastname: Parma
authors.forename: G
authors.initials: G
authors.lastname: Vassart
authors.forename: P
authors.initials: P
authors.lastname: Fondu
authors.forename: F
authors.initials: F
authors.lastname: Vertongen
mesh_terms: D000465:Algorithms; D001530:Belgium / Q000453:epidemiology; D003663:Decision Trees; D004641:Emigration and Immigration / Q000706:statistics & numerical data; D005787:Gene Frequency; D006580:Genetic Carrier Screening; D005820:Genetic Testing; D006453:Hemoglobinopathies / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000517:prevention & control*; D006801:Humans; D007231:Infant, Newborn; D020380:Needs Assessment; D015997:Neonatal Screening; D010819:Physician's Role; D011159:Population Surveillance; D011296:Prenatal Diagnosis; D014504:Urban Health / Q000706:statistics & numerical data*