Cyclopeptides from the bark of Discaria americana.
Two new cyclopeptides, named discarene C (1) and discarene D (2), have been isolated from the bark of Discaria americana, along with seven known cyclopeptide alkaloids. The structures of the new compounds were determined by spectroscopic methods, mainly NMR. The stereochemistry of the ring amino acid residues have been assigned by gas chromatography employing modified cyclodextrins as chiral stationary phases.
Giacomelli
S R
SR
Departamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria RS, Brazil.
Missau
F C
FC
Mostardeiro
M A
MA
da Silva
U F
UF
Dalcol
I I
II
Zanatta
N
N
Morel
A F
AF
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D001938:Brazil; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D007930:Leucine / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification*; D010649:Phenylalanine / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
D000470:Alkaloids; D010456:Peptides, Cyclic; C435825:discarene C; C435826:discarene D; D010649:Phenylalanine; D007930:Leucine