title: Child sexual abuse, poor parental care and adult depression: evidence for different mechanisms.
abstract: BACKGROUND
  Child sexual abuse (CSA) and poor parental care (neglect and institutional care) are associated with depression in adult life. Little is known about possible mechanisms underlying these associations.
  
  
  OBJECTIVE
  To examine the role of adult intimate-love relationships as differential mediators or moderators of the associations between CSA, poor parental care and adult depression.
  
  
  METHODS
  Sampling was carried out in two phases. In the first, questionnaires were sent to women aged 25-36 years in five primary care practices. Second-phase subjects for interview (n=198) were drawn from three strata defined on the basis of childhood adversities. Recalled childhood experiences and recent adult relationships and depression were assessed and rated independently. Frequencies of predictor and response variables, effect estimates and their confidence intervals were weighted back to the general population questionnaire sample.
  
  
  RESULTS
  The risk for depression associated with CSA was unaffected by quality of adult relationships, while the risk associated with poor parental care was substantially altered.
  
  
  CONCLUSIONS
  There may be different pathways linking CSA and poor parental care to adult depression.
authors.affiliation: Department of Psychiatry, University of Liverpool, UK. jonathan.hill@liverpool.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Hill
authors.forename: A
authors.initials: A
authors.lastname: Pickles
authors.forename: E
authors.initials: E
authors.lastname: Burnside
authors.forename: M
authors.initials: M
authors.lastname: Byatt
authors.forename: L
authors.initials: L
authors.lastname: Rollinson
authors.forename: R
authors.initials: R
authors.lastname: Davis
authors.forename: K
authors.initials: K
authors.lastname: Harvey
mesh_terms: D000328:Adult; D002648:Child; D002649:Child Abuse / Q000523:psychology*; D002675:Child, Preschool; D003866:Depressive Disorder / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D007326:Institutionalization; D007398:Interpersonal Relations; D008149:Love; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors