Convertases other than furin cleave beta-secretase to its mature form.
Pinnix
I
I
Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
Council
J E
JE
Roseberry
B
B
Onstead
L
L
Mallender
W
W
Sucic
J
J
Sambamurti
K
K
D000544:Alzheimer Disease / Q000201:enzymology; D053829:Amyloid Precursor Protein Secretases; D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000235:genetics / Q000378:metabolism*; D002460:Cell Line; D010450:Endopeptidases; D004792:Enzyme Precursors / Q000378:metabolism; D004795:Enzyme Stability; D045683:Furin; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D009154:Mutation; D011994:Recombinant Proteins / Q000378:metabolism; D012697:Serine Endopeptidases / Q000378:metabolism*; D013381:Subtilisins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D014162:Transfection
D004792:Enzyme Precursors; D011994:Recombinant Proteins; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D012697:Serine Endopeptidases; D013381:Subtilisins; D045683:Furin; D016282:Aspartic Acid Endopeptidases; C509284:BACE2 protein, human; C509280:BACE1 protein, human; C509282:Bace1 protein, mouse