Preventing schizophrenia and Alzheimer disease: comparative ethics.
Schizophrenia and Alzheimer disease are both diseases of the brain that involve genetic susceptibility factors and for which the prevention or delay of symptom onset are important research goals. This paper provides some comparisons between current preventive efforts in schizophrenia and Alzheimer disease, focusing on certain ethical features of these endeavors such as potential discrimination, misdiagnosis, and stigma.
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Center for Biomedical Ethics, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106-4976, USA. sgp2@po.cwru.edu
D000293:Adolescent; D000328:Adult; D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000235:genetics / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D003951:Diagnostic Errors; D004992:Ethics, Medical; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D007258:Informed Consent; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D011594:Psychometrics; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics / Q000517:prevention & control*