title: New aspects of clinical pathology and electro-physiological muscle disturbances in patients with history of trichinellosis.
abstract: Clinical studies performed in 44 patients, one, three, four, six or seven years after they had experienced trichinellosis demonstrated the persistence of various general and motor ailments in 88.7% of the patients. The persisting for many years antibodies against E/S antigen of Trichinella in 86.4% of examined patients seem to reflect chronic stimulation by the larvae which, as shown by parasitological and histopathological tests, survived longer and underwent gradual destruction in muscles. Bio-electric disturbances in muscles were most frequently of a mixed type, with prevalence of a neural type record. These observations illustrate a disturbed function of motor neurones and of impulse transmission at the myoneural junction in patients chronically infected with Trichinella.
authors.affiliation: Clinic of Parasitic and Tropical Diseases, KMUMS, Przybyszewskiego 49, Poznan, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Kociecka
authors.forename: K
authors.initials: K
authors.lastname: Bombicki
authors.forename: L
authors.initials: L
authors.lastname: Pielok
authors.forename: L
authors.initials: L
authors.lastname: Gustowska
mesh_terms: D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D000947:Antigens, Helminth / Q000276:immunology; D004576:Electromyography; D004797:Enzyme-Linked Immunosorbent Assay; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D018482:Muscle, Skeletal / Q000294:innervation / Q000473:pathology / Q000503:physiopathology*; D009412:Nerve Fibers / Q000502:physiology; D009431:Neural Conduction; D010146:Pain; D010543:Peroneal Nerve / Q000503:physiopathology; D013979:Tibial Nerve / Q000503:physiopathology; D014234:Trichinella / Q000276:immunology; D014235:Trichinellosis / Q000097:blood / Q000473:pathology* / Q000503:physiopathology*
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth