title: Point mutation detection technology for the new-century laboratory.
abstract: The READIT system represents the newest contribution to point mutation detection technology. Specifically, the system involves hybridizing DNA or RNA probes using phosphorylation chemistry and luciferase as the detection method. The two primary features that distinguish the READIT technology from the competition are its versatility and the ability of users to design its own probes. The automated genotype assignment and statistical analysis simplify the use of this system even more. In the year 2002 more than a million tests will be performed in molecular diagnostics with significant contributions from both research and private laboratories.(1) The most important attributes for laboratorians when reviewing a new technology are cost, accuracy, automation, and ease of use. The advent of unique point mutation detection technologies will certainly assist the role of the laboratory in demonstrating the positive impact of testing on future applications of these technologies. Cost savings, accuracy, simplicity, and flexible throughput are the must-have features of successful point mutation detection technologies for the new-century laboratory.
authors.affiliation: Millennium Strategies, Madison, WI 53717, USA. PamelaBean@home.com
authors.forename: P
authors.initials: P
authors.lastname: Bean
authors.forename: A
authors.initials: A
authors.lastname: Ryan
authors.forename: G J
authors.initials: GJ
authors.lastname: Tsongalis