title: Moderate to severe iodine deficiency in three endemic goitre areas from the Black Sea region and the capital of Turkey.
abstract: Endemic goitre is still an important and underestimated health concern in Turkey. The overall prevalence had been calculated as 30.3% by palpation in a national survey conducted in 1995. However, direct evidence that iodine deficiency (ID) is the major cause of the endemic were lacking until now. We measured sonographic thyroid volumes (STV), urinary iodine concentrations (UIC) in 1226 school age children (SAC) (9-11 year old) from Ankara the capital of Turkey located in the central Anatolia, and three highly endemic goitre areas of the Black Sea region. A considerable number of school age children (SAC) were found to have STV exceeding the recommended upper normal limits for their age and gender obtained from iodine-replete European children (i.e. 26.7, 40.3, 44.8 and 51.7% of children from Ankara, Kastamonu, Bayburt and Trabzon respectively). UIC indicated moderate to severe ID in these areas with median concentrations of 25.5, 30.5, 16.0 and 14 microg/L respectively. This study showed severe to moderate ID as the primary etiological factor for the goitre endemic observed in Ankara and the Black Sea region of Turkey.
authors.affiliation: Department of Endocrinology and Metabolism, University of Ankara School of Medicine, Sihhiye, Turkey. gurbuz.erdogan@temd.org.tr
authors.forename: G
authors.initials: G
authors.lastname: Erdoğan
authors.forename: M F
authors.initials: MF
authors.lastname: Erdoğan
authors.forename: F
authors.initials: F
authors.lastname: Delange
authors.forename: H
authors.initials: H
authors.lastname: Sav
authors.forename: S
authors.initials: S
authors.lastname: Güllü
authors.forename: N
authors.initials: N
authors.lastname: Kamel
mesh_terms: D002648:Child; D005260:Female; D006043:Goiter, Endemic / Q000175:diagnosis / Q000453:epidemiology*; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D007455:Iodine / Q000172:deficiency*; D008297:Male; D012307:Risk Factors; D012424:Rural Population; D012720:Severity of Illness Index; D017678:Sex Distribution; D014421:Turkey / Q000453:epidemiology; D014505:Urban Population
chemical_list: D007455:Iodine