Intrahepatic biliary lesions after orthotopic liver transplantation.
Intrahepatic biliary lesions (IBL) are rare (2-9%) after orthotopic liver transplantation (OLT). The aim was to evaluate the incidence, etiology and outcome. In nine years, a total 532 OLTs were performed in 481 patients. Twenty-four patients developed IBL. Eight were due to HAT, seven to ABOI, three to CDR and six to PI. The time until diagnosis of HAT is longest in patients (14+/-6) with IBL. ABOI is another cause of IBL. CDR is a rare cause of IBL, however when it takes place, patients must undergo Rtx. Finally, PI is a relevant cause of IBL. In order to suppress the incidence of IBL we should consider 1) the systematic use of Doppler-Ultrasound; 2) emergency reoperation of patients with HAT, 3) avoid ABOI in OLT; 4) Rtx in cases of CDR, and 5) OLT should still be performed as an emergency procedure.
Rull
R
R
Liver Transplant Unit, Hospital Clinic, University of Barcelona, Spain.
Garcia Valdecasas
J C
JC
Grande
L
L
Fuster
J
J
Lacy
A M
AM
González
F X
FX
Rimola
A
A
Navasa
M
M
Iglesias
C
C
Visa
J
J
D000017:ABO Blood-Group System; D000328:Adult; D001649:Bile Duct Diseases / Q000209:etiology*; D001653:Bile Ducts, Intrahepatic / Q000098:blood supply / Q000293:injuries; D001787:Blood Group Incompatibility / Q000150:complications; D002908:Chronic Disease; D005260:Female; D006084:Graft Rejection / Q000150:complications; D006499:Hepatic Artery; D006801:Humans; D007511:Ischemia / Q000209:etiology; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation / Q000009:adverse effects; D013927:Thrombosis / Q000150:complications / Q000209:etiology
D000017:ABO Blood-Group System