title: Acute abdominal symptoms in malignant hypertension: clinical presentation in five cases.
abstract: Malignant hypertension causes anatomical and functional damage in several target organs, in particular brain, retina, heart and kidneys. Although vascular lesions in the gastroenteric tract are known to occur in several instances, their clinical relevance is unknown. In this study five cases of malignant hypertension, presenting with acute abdominal symptoms, are reported. A history of essential arterial hypertension was present in three patients; while one patient had a previous diagnosis of renovascular hypertension and one patient had renoparenchymal hypertension. However, in all cases the antihypertensive treatment was discontinued and inadequate before the accelerated malignant phase. The acute abdominal symptoms at presentation were due to intestinal infarction in 3 patients and acute pancreatitis in 2 patients. One patient with intestinal infarction died of postoperative cardiogenic shock. Our data are in agreement with previous reports describing the possible intra-abdominal complications of malignant hypertension. The therapeutic approach in such conditions should always consider an effective antihypertensive treatment in conjunction with surgical options.
authors.affiliation: Istituto di Patologia Medica, Universita Cattolica Del Sacro Cuore, Roma, Italia.
authors.forename: C
authors.initials: C
authors.lastname: Guerrera
authors.forename: F
authors.initials: F
authors.lastname: Colivicchi
authors.forename: R
authors.initials: R
authors.lastname: Pola
authors.forename: F
authors.initials: F
authors.lastname: Travaglino
authors.forename: G
authors.initials: G
authors.lastname: Filice
authors.forename: G
authors.initials: G
authors.lastname: Guerrera
authors.forename: D
authors.initials: D
authors.lastname: Melina
mesh_terms: D000208:Acute Disease; D000328:Adult; D006801:Humans; D006974:Hypertension, Malignant / Q000150:complications*; D007238:Infarction / Q000150:complications*; D007422:Intestines / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications*; D013577:Syndrome