Polyamine oxidase activity in sera of depressed and schizophrenic patients after ECT treatment.
High level of polyamine oxidase activity is detected in sera of depressed as well as in schizophrenic patients. ECT treatment of depressed and schizophrenic patients reduced significantly the level of polyamine oxidase activity in their sera. After ECT treatment, clinically improved depressed and schizophrenic subjects were found to have sera polyamine oxidase activity not significantly differ from that of normal subjects. Possible biochemical mechanisms, which link polyamine oxidase activity, schizophrenia, depression and ECT effect are discussed here.
Dahel
K A
KA
Dept. of Chemistry, College of Science University of Mosul, Iraq.
Al-Saffar
N M
NM
Flayeh
K A
KA
D003863:Depression / Q000097:blood / Q000201:enzymology* / Q000628:therapy; D004565:Electroconvulsive Therapy; D006801:Humans; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000097:blood*; D012559:Schizophrenia / Q000097:blood / Q000201:enzymology* / Q000628:therapy; D000097667:Polyamine Oxidase
D000587:Oxidoreductases Acting on CH-NH Group Donors; D000097667:Polyamine Oxidase