title: [Effects of the spaceflight factors on the immune system].
abstract: The paper summarizes the main trends and milestones of space immunology starting with initial ground-based investigations with animals to recent experiments in piloted and automatic space vehicles data of which have been highlighted in numerous publications. There is a brief description of lines and results of investigations with participation of cosmonauts, and using laboratory animals and cell cultures. The author dwells upon the present-day notion of immune responses to extreme conditions and future topics of investigations.
authors.affiliation: Aviakosmicheskaya i Ekologicheskaya Meditsina, Russia.
authors.forename: D O
authors.initials: DO
authors.lastname: Meshkov
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology; D001402:B-Lymphocytes / Q000502:physiology; D002490:Central Nervous System / Q000502:physiology; D005426:Flight, Animal; D006801:Humans; D007107:Immune System / Q000502:physiology*; D007136:Immunoglobulins / Q000276:immunology; D013026:Space Flight; D013601:T-Lymphocytes / Q000502:physiology; D014893:Weightlessness
chemical_list: D000942:Antigens, Bacterial; D007136:Immunoglobulins