[Assessment of exhaled NO concentration in monitoring radiation pneumonitis in patient who underwent thoracic radiotherapy for lung cancer].
To monitor radiation pneumonitis, we assessed the exhaled nitrogen oxide (NO) level in patient with lung cancer. A 73-year-old man with idiopathic interstitial pneumonitis underwent thoracic radiotherapy without chemotherapy for squamous cell lung cancer (T2N1M0). He showed elevation of exhaled NO level at 30 Gy-50 Gy, after a decrease at 10-20 Gy. He also showed an abnormal shadow on CT examination at 50 Gy. Although exhaled NO may have had the benefit of predicting radiation pneumonitis before severe clinical symptom appeared, he died three months after radiotherapy because of worsening of the radiation pneumonitis.
Toyokawa
K
K
Department of Radiology, Toneyama National Hospital Radiology.
Yamazaki
H
H
Masahiko
K
K
Inoue
T
T
Inoue
T
T
D000368:Aged; D001944:Breath Tests; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods*; D009569:Nitric Oxide / Q000032:analysis*; D017564:Radiation Pneumonitis / Q000175:diagnosis* / Q000209:etiology*; D014057:Tomography, X-Ray Computed
D009569:Nitric Oxide