title: Regulation of clathrin-coated vesicle formation.
abstract: The formation of clathrin-coated pits at the plasma membrane requires the concerted action of many different molecules. The real challenge lies in determining the hierarchy of these interactions. We are using assays in both intact and permeabilized cells to dissect the temporal requirements for clathrin-coated vesicle formation, and also to examine the role of phosphorylation of the coat proteins.
authors.affiliation: Division of Molecular Cell Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK.
authors.forename: E
authors.initials: E
authors.lastname: Hill
authors.forename: O
authors.initials: O
authors.lastname: Olusanya
authors.forename: J
authors.initials: J
authors.lastname: van der Kaay
authors.forename: C P
authors.initials: CP
authors.lastname: Downes
authors.forename: P D
authors.initials: PD
authors.lastname: Andrews
authors.forename: J R
authors.initials: JR
authors.lastname: Swedlow
authors.forename: E
authors.initials: E
authors.lastname: Smythe
mesh_terms: D033942:Adaptor Proteins, Vesicular Transport; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D022163:Clathrin-Coated Vesicles / Q000502:physiology*; D008565:Membrane Proteins / Q000378:metabolism*; D010766:Phosphorylation
chemical_list: D033942:Adaptor Proteins, Vesicular Transport; D002352:Carrier Proteins; D008565:Membrane Proteins; D000255:Adenosine Triphosphate