Reconciling differences in effective solute removal between intermittent and continuous therapies.
Solute removal by various forms of renal replacement therapy (RRT) differs from that occurring in the native kidney in several ways. Among the dialytic therapies, the relationship between clearance and mass removal rate may differ substantially. The purpose of this article is to review the various approaches that have been proposed to account for this differing relationship among the various types of RRT. Specific quantitative approaches along with clinical applications are provided.
Clark
W R
WR
Hemodialysis Research Laboratory, Renal Division, Baxter Healthcare Corp., Wishard Hospital/Myers Building D711, 1001 West 10th St., Indianapolis, IN 46202, USA. clarkbi@baxter.com
Ronco
C
C
D006801:Humans; D007674:Kidney Diseases / Q000628:therapy*; D010531:Peritoneal Dialysis, Continuous Ambulatory; D017582:Renal Replacement Therapy; D014508:Urea / Q000097:blood
D014508:Urea