[Clinical study of puerarin in treatment of patients with unstable angina].
OBJECTIVE
To observe the clinical efficacy of puerarin in treating patients with unstable angina (UA).


METHODS
Frequency of angina events, consumed doses of nitrates, heart rate, blood pressure, rest electrocardiogram (ECG) and myocardial oxygen consumption were observed before and after drug therapy in puerarin group (21 cases) and control group (18 cases) respectively.


RESULTS
The puerarin group not only showed more effective than that in control group in reducing frequency of angina events and consumed doses of nitrates and improving abnormal rest ECG, but also appeared to be preferable to the control group in reducing myocardial oxygen consumption and increasing exercise duration (P < 0.05).


CONCLUSIONS
Puerarin is a safe and effective drug in treating patients with UA.
Zhao
Z
Z
Department of Geriatrics, Affiliated Hospital of Hubei Medical University, Wuhan 430060.
Yang
X
X
Zhang
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D000789:Angina, Unstable / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007529:Isoflavones / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D014665:Vasodilator Agents / Q000627:therapeutic use*
D007529:Isoflavones; D014665:Vasodilator Agents; C033607:puerarin