[Study on treatment of blood stasis syndrome of chronic prostatitis using prostatitis decoction and its extract capsule].
OBJECTIVE
To test and verify the effects of prostatitis decoction and its capsule on the treatment of chronic prostatitis with blood stasis Syndrome, and its therapeutic mechanism.


METHODS
Five hundred and sixty-one Patients were treated for 2 months, decoction group 322 cases, and capsule group 239 cases. As control group, 95 cases were treated with Qianliekang tablets. Expressed prostatic secretion(EPS)-pH and Zn content were measured before and after treatment. Observation on hemorheology and microcirculation disturbance with animal experiments were conducted.


RESULTS
The cure rate of Prostatitis decoction and capsule groups was 65.8%, and 54.4% respectively, that of control group was only 17.9%. EPS-pH and Zn were markedly improved after Prostatitis decoction treatment. Experimental work revealed that Prostatitis decoction and its capsule had lowered the whole blood viscosity, thrombocyte adhesiveness rate and dry weight of thrombus in blood stasis rabbit model; and on rats model of microcirculation disturbance caused by adrenalin, the Prostatitis decoction and its capsules had obviously delayed the occurrence of reduction and stopping of blood flow in arterioles.


CONCLUSIONS
Prostatitis decoction (capsule) was effective in treating chronic prostatitis.
Zhang
Y
Y
Guang'anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing 100053.
Liu
Y
Y
D000328:Adult; D000818:Animals; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D018056:Hemorheology; D006801:Humans; D008297:Male; D051379:Mice; D008875:Middle Aged; D011472:Prostatitis / Q000097:blood / Q000188:drug therapy* / Q000378:metabolism; D011817:Rabbits; D011897:Random Allocation; D015032:Zinc / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D015032:Zinc