title: Fast analysis of antibacterial isothiazolones by capillary electrophoresis.
abstract: Some technical aspects influencing the total time of CE analysis are discussed. A high throughput electrophoretic system based on micellar electrokinetic chromatography (MEKC) is demonstrated as an example. A short capillary, strong electric field, alkaline buffer (pH 9.5) generating strong electroosmotic flow, and parallel hydrodynamic pressure allow the separation of two uncharged isothiazolone derivatives within 45 s.
authors.affiliation: Centre of Bioanalytical Research, Palacký University, Olomouc, Czech Republic. bartak@risc.upol.cz
authors.forename: P
authors.initials: P
authors.lastname: Barták
authors.forename: P
authors.initials: P
authors.lastname: Bednár
authors.forename: D
authors.initials: D
authors.lastname: Friedecký
authors.forename: A
authors.initials: A
authors.lastname: Haviger
authors.forename: J
authors.initials: J
authors.lastname: Sevcík
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis*; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D013844:Thiazoles / Q000032:analysis*
chemical_list: D000890:Anti-Infective Agents; D013844:Thiazoles