Automated mode-of-action detection by metabolic profiling.
Rapid classification and identification of the mode-of-action of bioactive compounds applied to plants can be achieved by a robust and easy-to-use metabolic-profiling method. This method uses artificial neural network analysis of one-dimensional proton NMR spectra of aqueous plant extracts to rapidly classify changes in the total metabolic profile caused by application of crop protection chemicals.
Aranìbar
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BASF Agro Research, Princeton, NJ 08543-0400, USA.
Singh
B K
BK
Stockton
G W
GW
Ott
K H
KH
D001331:Automation; D009682:Magnetic Resonance Spectroscopy; D016571:Neural Networks, Computer; D003313:Zea mays / Q000378:metabolism*