title: Anetoderma associated with antiphospholipid antibodies: case report and review of the literature.
abstract: The association of primary anetoderma (PA) with antiphospholipid antibodies (APAs; with or without criteria of primary antiphospholipid syndrome) has been observed repeatedly and a possible pathogenic significance of this asssociation has been hypothesized. We report the case of a 21-year-old-woman who developed anetodermic lesions on her upper trunk and arms. The presence of APAs was demonstrated, but no diagnostic criteria of systemic lupus erythematosus were present. A review of the literature disclosed 20 previously reported patients presenting this peculiar association. Thrombotic phenomena, represented by spontaneous abortions or venous thrombosis, are a frequent complication in this setting. Taking these observations into account a systematic search for APAs in patients with PA seems advisable.
authors.affiliation: Department of Dermatology, Hospital de Palamós, Girona, Spain. jromanid@medynet.com
authors.forename: J
authors.initials: J
authors.lastname: Romaní
authors.forename: F
authors.initials: F
authors.lastname: Pérez
authors.forename: M
authors.initials: M
authors.lastname: Llobet
authors.forename: M
authors.initials: M
authors.lastname: Planagumá
authors.forename: R M
authors.initials: RM
authors.lastname: Pujol
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D016736:Antiphospholipid Syndrome / Q000473:pathology*; D001284:Atrophy / Q000473:pathology*; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D012720:Severity of Illness Index; D012871:Skin Diseases / Q000276:immunology* / Q000473:pathology*
chemical_list: D017152:Antibodies, Antiphospholipid