title: Eosinophilic granuloma as a form of inflammatory reaction. A case report.
abstract: Eosinophilic granuloma consists of the proliferation and/or accumulation of Langerhans cells in the bones, generally of the cranium and face, as a uni- or multifocal cystic lesion. It is considered to be a localized chronic form of Langerhans cell disease. The most frequent oral location is the posterior part of the mandible, where the bone lesion often gives rise to lesions of the overlying soft tissues. We report a case showing bilateral involvement of the upper jaw and unilateral involvement of the mandible. The eosinophilic granulomas arose in association with odontogenic periapical infectious processes, suggesting that this disorder may be a form of inflammatory response.
authors.affiliation: Servicio de Anatomía Patológica, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, La Coruña, España.
authors.forename: M
authors.initials: M
authors.lastname: Diniz Freitas
authors.forename: P
authors.initials: P
authors.lastname: Madriñán Graña
authors.forename: J
authors.initials: J
authors.lastname: Antúnez López
authors.forename: P
authors.initials: P
authors.lastname: Gándara Vila
authors.forename: J M
authors.initials: JM
authors.lastname: Gándara Rey
authors.forename: A
authors.initials: A
authors.lastname: García García
mesh_terms: D001706:Biopsy; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D004803:Eosinophilic Granuloma / Q000473:pathology*; D006801:Humans; D007801:Langerhans Cells / Q000473:pathology; D008297:Male; D008336:Mandibular Diseases / Q000473:pathology*; D008439:Maxillary Diseases / Q000473:pathology*; D008875:Middle Aged; D010014:Osteolysis / Q000175:diagnosis; D010484:Periapical Granuloma / Q000175:diagnosis