Effect of dietary protein on zinc phosphide toxicity in albino rats (Rattus norvegicus).
Adult male and female albino rats (R. norvegicus) were administered rodenticide, zinc phosphide ranging from 4, 2, 1, 0.5, 0.25 and 0.125% in the diet containing 10(A), 17(B) and 24%(C) protein. Zinc phosphide induced 100% mortality at 4, 2, 1, 0.5% in diet A; 4 and 2% in diet B; and 4% in diet C. The results reveal influence of dietary protein in modulating the toxicity of zinc phosphide, suggesting that greater caution should be exercised while formulating its baits for effectiveness. The results also suggest that baits having 10% protein are more suitable to carry the rodenticide from view point of acceptability and efficacy towards the target species.
Muktha Bai
K
K
Food Protectants and Infestation Control Department, Central Food Technological Research Institute, Mysore, India.
D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D010720:Phosphines / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D012378:Rodenticides / Q000008:administration & dosage / Q000633:toxicity*; D017967:Zinc Compounds / Q000008:administration & dosage / Q000633:toxicity*
D004044:Dietary Proteins; D010720:Phosphines; D012378:Rodenticides; D017967:Zinc Compounds; C009701:zinc phosphide