title: [Byproducts of grapes and carbohydrate metabolism].
abstract: One of the important problems in treatment of diabetes is the preventing of considerable fluctuations of level of a glucose in a blood during day. In this connection it is recommended to reduce fat consumption, to prefer rations with a high content of dietary fibers. In experiences on rats is found, that a blood sedimentation rate, level of a hemoglobin did not differ from control magnitudes in conditions of long-lived trials of vegetable preparations. Amounts of reticulocytes, erythrocytes, lymphocytes, hematocrit were normal. An amount of thrombocytes and leukocytic formula practically did not change. Is established, that the glucose level in time gaps was reliably reduced when introduction of grape residues dietary fibers (5.9 +/- 0.7 mmol/l) and dietary fibers of grape seeds press cake (5.7 +/- 0.8 mmol/l) in a conventional ration as distinct from control (6.4 +/- 0.8 mmol/l). The low level content of dietary fibers in ration (5%) is reduce a level of a glucose on an empty stomach up to 6.8 +/- 1.4 mmol/l. The content of total protein in all groups of rats was in physiological norm and averaged 70-76 +/- 3 g/l. The investigated preparations of grape residues dietary fibers and dietary fibers of grape seeds press cake are nontoxic, are well tolerated laboratory animal, and can be recommended as the treatment and prophylactic components for correction of carbohydrate and lipide dysbolism.
authors.forename: L F
authors.initials: LF
authors.lastname: Shchelkunov
mesh_terms: D000818:Animals; D050260:Carbohydrate Metabolism; D004043:Dietary Fiber; D051381:Rats; D017208:Rats, Wistar; D027843:Vitis