title: The role of Gd-enhanced three-dimensional MRI fast low-angle shot (FLASH) in the evaluation of symptomatic lumbosacral nerve roots.
abstract: In the field of lumbar spine disorders, three-dimensional (3-D) magnetic resonance imaging (MRI) can clearly depict a lumbar nerve root from the distal region to the dorsal root ganglion. In this study, we used a gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA) enhanced-three-dimensional (3-D) fast low-angle shot (FLASH) sequence when examining lumbosacral disorders. The subjects were 33 patients (14 men and 19 women) in whom lumbosacral neural compression had been diagnosed clinically. Twenty-one patients had lumbar disc herniation, 11 had lumbar spinal stenosis, and 1 had lumbar radiculopathy caused by rheumatoid arthritis. Five subjects with low back pain were also studied as a control group. In all patients and in all 5 of the controls, the dorsal root ganglion of every root was enhanced clearly. There was no root enhancement in the 5 controls. Enhancement of the symptomatic nerve roots, caused by compression, was found in 11 of the 33 patients. All 11 patients had radiculopathy, and muscle weakness was more frequent in patients with enhanced nerve roots than in those without enhancement. There was no enhancement of the cauda equina, even in the patients with cauda syndrome. The enhancement effect may reflect some pathological condition of the compressed nerve root and needs to be studied further.
authors.affiliation: Department of Orthopaedic Surgery, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi-machi, Kawachi, Tochigi 329-0498, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Kikkawa
authors.forename: H
authors.initials: H
authors.lastname: Sugimoto
authors.forename: K
authors.initials: K
authors.lastname: Saita
authors.forename: H
authors.initials: H
authors.lastname: Ookami
authors.forename: S
authors.initials: S
authors.lastname: Nakama
authors.forename: Y
authors.initials: Y
authors.lastname: Hoshino
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D021621:Imaging, Three-Dimensional; D007405:Intervertebral Disc Displacement / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013130:Spinal Stenosis / Q000175:diagnosis
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA