title: Synthesis and application of chiral P,N-ligands with pseudo-meso and pseudo-C(2) symmetry.
abstract: [structure: see text] Two diastereoisomeric P,N-ligands, (S,S)-1 and (R,S)-1, were synthesized and assessed in palladium-catalyzed allylic alkylations. With rac-1,3-diphenylpropenyl acetate as substrate, ligand (S,S)-1, with "pseudo-C(2)" symmetry, exhibited higher reactivity and higher enantioselectivity than the "pseudo-meso" ligand (R,S)-1, whereas reversal reactivity and selectivity were observed with rac-3-cyclohexenyl acetate.
authors.affiliation: Department of Chemistry, Organic Chemistry, Royal Institute of Technology, SE-100 44 Stockholm, Sweden.
authors.forename: R
authors.initials: R
authors.lastname: Stranne
authors.forename: J L
authors.initials: JL
authors.lastname: Vasse
authors.forename: C
authors.initials: C
authors.lastname: Moberg