Alpha-like activity in terminal stage of Creutzfeldt-Jakob disease.
We report a case of Creutzfeldt-Jakob disease showing various changes in electroencephalogram (EEG) throughout the course of the disease. The patient's EEG patterns showed periodic synchronous discharge in the intermediate stage of the disease, delta activity in the advanced stage and alpha-like activity in the terminal stage. The mechanism generating alpha-like activity may resemble, at least in part, that of an alpha coma.
Asai
Y
Y
Departments of Neurology and Neuropathology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan. yasu@grape.med.tottori-u.ac.jp
Shimoda
M
M
Sasaki
K
K
Nakayasu
H
H
Takeshima
T
T
Miyata
H
H
Ohama
E
E
Nakashima
K
K
D000368:Aged; D000513:Alpha Rhythm; D001921:Brain / Q000473:pathology / Q000503:physiopathology*; D007562:Creutzfeldt-Jakob Syndrome / Q000473:pathology / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D019452:Terminally Ill