title: [A serial histological study on suture expansion osteogenesis for cleft palate closure].
abstract: OBJECTIVE
  The purpose of this study was to know the process of tissue response and regeneration in the palato-maxillary suture under tensile forces.
  
  
  METHODS
  Sutural tissue changes after 3, 7, 14, 28, 56 days of suture expansion were examined histologically and fluorescently.
  
  
  RESULTS
  It was found that a cyst-like zone appeared in the conjuncture of bony front and sutural connective tissue at the early stage of sutural expansion. Then a great amount of osteoblasts and fibroblasts proliferated. New bone deposited along the septum and the front of the cyst until the new bone front formed and the suture restored its original morphology.
  
  
  CONCLUSIONS
  The findings suggested that sutural expansion be a process of bone tissue regeneration and fibrous tissue repair.
authors.affiliation: General Hospital and Postgraduate College of People's Liberation Army, Beijing 100853, PR China.
authors.forename: C
authors.initials: C
authors.lastname: Liu
authors.forename: R
authors.initials: R
authors.lastname: Song
authors.forename: Y
authors.initials: Y
authors.lastname: Song
mesh_terms: D000818:Animals; D002972:Cleft Palate / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D010006:Osteoblasts / Q000473:pathology; D010012:Osteogenesis; D010155:Palatal Expansion Technique; D021362:Palate, Hard / Q000473:pathology* / Q000601:surgery; D011897:Random Allocation; D013536:Suture Techniques; D013718:Tensile Strength