title: Is there a disassociation of maximal oxygen consumption and maximal cardiac output?
abstract: OBJECTIVE
  The purpose of the present study was to determine whether maximal cardiac output (Q) is affected by the duration of the maximal exercise test.
  
  
  METHODS
  Nine healthy men (N = 6) and women (N = 3) performed three separate maximal treadmill exercise tests, separated by at least 24 h, and underwent a body composition assessment by hydrostatic weighing, all within a 2-wk period. A baseline maximal exercise test was performed to establish VO(2max). The second and third tests, assigned randomly, were designed to elicit the subjects' predetermined VO(2max) in either 6 or 12 min. Heart rate (HR), blood pressure (BP), minutes of ventilation, and oxygen consumption (VO(2)) were measured during all tests. At the end of the 6- and 12-min tests, Q was measured using an acetylene rebreathing technique. Stroke volume (SV), mean arterial pressure (MAP), total peripheral resistance (TPR), and arteriovenous O(2) difference were calculated using standard equations.
  
  
  RESULTS
  Repeated-measures ANOVA indicated that there were no significant differences in HR and VO(2max) between the baseline, 6-min, and 12-min tests. Paired t-tests revealed significantly greater Q (25.1 +/- 5.6 vs 23.7 +/- 5.2 L.min-1) and SV (138.3 +/- 31.5 vs 130.5 +/- 31.2 mL) in the 6- versus 12-min tests, respectively. There were no significant differences in systolic BP, diastolic BP, MAP, TPR, or arteriovenous O(2) difference.
  
  
  CONCLUSIONS
  Despite there being no difference in VO(2max) between the two tests, the 6-min maximal exercise test resulted in a significantly greater Q than the 12-min test, because of a significantly greater SV. Thus, there was a disassociation between VO(2) and Q during maximal exercise.
authors.affiliation: Department of Human Kinetics, University of Wisconsin-Milwaukee, Milwaukee, WI 53201, USA. smccole@uwm.edu
authors.forename: S D
authors.initials: SD
authors.lastname: McCole
authors.forename: A M
authors.initials: AM
authors.lastname: Davis
authors.forename: P T
authors.initials: PT
authors.lastname: Fueger
mesh_terms: D000328:Adult; D002302:Cardiac Output; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D010101:Oxygen Consumption