title: Endometrial stromal sarcoma of the rectosigmoid colon arising in extragonadal endometriosis and revealed by portal vein thrombosis.
abstract: Malignant transformation is an infrequent complication of endometriosis. The ovary is the primary site in 76% of cases, and extragonadal sites are identified in 24%. Endometrioid carcinoma is the most common histologic type; sarcoma is very rare. We report a case of low-grade endometrial stromal sarcoma of the rectosigmoid colon presenting with epigastric pain due to portal vein thrombosis. This tumor arose from extragonadal endometriosis in a 61-year-old woman and was treated by surgical resection. The main differential diagnosis of this unusual colonic neoplasm includes primary mesenchymal tumors, such as gastrointestinal stromal tumors.
authors.affiliation: Department of Pathology, Hôpital Saint-Antoine, AP-HP, 184 rue faubourg St-Antoine, 75012 Paris, France. najat.mourra@free.fr
authors.forename: N
authors.initials: N
authors.lastname: Mourra
authors.forename: E
authors.initials: E
authors.lastname: Tiret
authors.forename: Y
authors.initials: Y
authors.lastname: Parc
authors.forename: P
authors.initials: P
authors.lastname: de Saint-Maur
authors.forename: R
authors.initials: R
authors.lastname: Parc
authors.forename: J F
authors.initials: JF
authors.lastname: Flejou
mesh_terms: D002471:Cell Transformation, Neoplastic; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D004715:Endometriosis / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010146:Pain; D011169:Portal Vein; D018203:Sarcoma, Endometrial Stromal / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis*