Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain.
The axon guidance molecule netrin-1 has been implicated in the midline repulsion of developing cranial motor axons. We have examined expression patterns of the netrin receptors UNC5H1 and DCC in embryonic rat hindbrains, in combination with labelling of developing motor neurons. We found that UNC5H1 expression colocalised with a number of cranial motor neuron subpopulations from embryonic day 11 (E11) to E14, while DCC was expressed by motor neurons at E12.
Barrett
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MRC Centre for Developmental Neurobiology, 4th Floor New Hunt's House, King's College, Guy's Campus, SE1 1UL, London, UK.
Guthrie
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D000818:Animals; D015870:Gene Expression; D020869:Gene Expression Profiling; D016163:Genes, DCC; D017403:In Situ Hybridization; D009046:Motor Neurons / Q000378:metabolism*; D000075386:Netrin Receptors; D051381:Rats; D011956:Receptors, Cell Surface / Q000235:genetics*; D012249:Rhombencephalon / Q000166:cytology / Q000196:embryology* / Q000378:metabolism
D000075386:Netrin Receptors; D011956:Receptors, Cell Surface