[Sulfasalazine neurotoxicity].
We report a case of seizures with acute encephalopathy in a female patient under sulfasalazine treatment for polyarthritis. Neurotoxicity secondary to sulfasalazine was suspected. This side effect has seldom been reported in the literature.
Chadenat
M L
ML
Service de Médecine Interne 2 (Pr Rouveix), Hôpital Ambroise-Paré, 9, avenue Charles-de-Gaulle, 92104 Boulogne Cedex. marie-laurie.chadenat@apr.ap-hop-paris.fr
Morelon
S
S
Dupont
C
C
Dechy
H
H
Raffin-Sanson
M L
ML
Dorra
M
M
Rouveix
E
E
D000208:Acute Disease; D000328:Adult; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001168:Arthritis / Q000150:complications / Q000188:drug therapy; D004660:Encephalitis / Q000139:chemically induced*; D004827:Epilepsy / Q000150:complications; D005260:Female; D006801:Humans; D012460:Sulfasalazine / Q000009:adverse effects*
D018501:Antirheumatic Agents; D012460:Sulfasalazine