[The effects of zinc on liver metallothionein in scalded rats].
OBJECTIVE
To investigate the changes in liver metallothionein (MT) in scalded rats.


METHODS
The scalded rats in deficient zinc condition were fed with diets containing zinc 4 micrograms/g, 10 micrograms/g, and 80 micrograms/g respectively. The changes in serum zinc, liver zinc and liver MT were observed.


RESULTS
The serum zinc decreased, liver zinc and MT increased. The higher diet zinc levels were, The higher serum zinc, liver zinc and MT became. The correlation analysis showed that the changes between liver zinc level and liver MT was positive relationship(r = 0.85, P < 0.01).


CONCLUSIONS
Serum zinc decrease, liver zinc increase after burn. This is connect with increment of MT synthesis in liver, zinc is inducer to MT. It can improve synthesis of liver MT.
Li
L
L
Burn Institute, 304th Hospital of People's Liberation Army, Beijing 100037.
Guo
Z
Z
Zhao
L
L
D000818:Animals; D002056:Burns / Q000378:metabolism*; D008297:Male; D008668:Metallothionein / Q000378:metabolism*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D015032:Zinc / Q000172:deficiency / Q000494:pharmacology*
D008668:Metallothionein; D015032:Zinc