[Immunological marker activity in first episode schizophrenic patients].
We evaluated immune-inflammatory markers in 32 first-episode schizophrenic patients during exacerbation of symptoms and during clinical improvement. Mean concentrations of sIL-2R and IFN-g was higher and mean concentration of sIL-6R was lower in cell cultures from blood of schizophrenic patients than in normal controls and there was no difference in IL-2 concentration. There was no correlation between concentrations of cytokines and demographic and clinical data. Our results may suggest that immune system disturbances could be observed in schizophrenia at the onset of the disease.
Szulc
A
A
Klinika Chorób Psychicznych Akademii Medycznej w Białymstoku.
Galińska
B
B
Konarzewska
B
B
Gudel-Trochimowicz
I
I
Popławska
R
R
D000328:Adult; D015415:Biomarkers; D016207:Cytokines / Q000097:blood / Q000276:immunology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D012563:Schizophrenia, Paranoid / Q000175:diagnosis / Q000276:immunology* / Q000534:rehabilitation; D012720:Severity of Illness Index
D015415:Biomarkers; D016207:Cytokines