Neutrophilic fixed drug eruption.
A 49-year-old man presented with a reproducible, localized amoxycillin-clavulanic acid-induced eruption. The histopathology from lesional skin revealed a neutrophilic dermatosis. These histological findings have not been reported in previous fixed drug eruptions. A brief review is undertaken comparing fixed drug eruption and the group of neutrophilic dermatoses with our case presentation. We propose a new entity of neutrophilic fixed drug eruption.
Agnew
K L
KL
Department of Dermatology, Green Lane Hospital, Auckland, New Zealand.
Oliver
G F
GF
D000005:Abdomen; D000284:Administration, Oral; D000658:Amoxicillin / Q000008:administration & dosage / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001415:Back; D019818:Clavulanic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000145:classification / Q000209:etiology* / Q000473:pathology; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils; D012867:Skin / Q000293:injuries; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology; D014946:Wound Infection / Q000517:prevention & control; D014951:Wounds, Stab
D000900:Anti-Bacterial Agents; D019818:Clavulanic Acid; D000658:Amoxicillin