Effect of fibroids on cumulative probability of pregnancy in women taking follicle maturing drugs without assisted reproductive technology.
OBJECTIVE
To determine if the presence of uterine fibroids adversely affect in vivo conception rates.


METHODS
Pelvic ultrasound evaluation of the presence or absence of fibroids in consecutive infertility patients not treated with assisted reproductive technology in a two-year period. Conception outcome noted. Data analyzed according to the presence or absence of fibroids.


RESULTS
No difference in cumulative probability of pregnancy after five months was seen in patients with or without the presence of fibroids. There were no confounding variables found that could have skewed the pregnancy rates in one direction or the other.


CONCLUSIONS
In general the presence of fibroids do not adversely affect conception outcome for in vivo pregnancies. However, since the majority of the fibroids were small (< 6 cm) and were not submucosal and did not compress the endometrial cavity, larger studies are needed to address specific subtypes and circumstances on pregnancy outcome.
Wang
W
W
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Copper Hospital/University Medical Center, Department of Obstetrics and Gynecology, USA.
Check
J H
JH
Dietterich
C
C
Lurie
D
D
D000328:Adult; D005260:Female; D005306:Fertilization / Q000502:physiology*; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D015993:Life Tables; D008297:Male; D010062:Ovulation Induction; D011247:Pregnancy; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*