[The changes of calcitonin gene-related peptide (CGRP)-containing nerve fibers in adrenal gland of burned rats].
OBJECTIVE
To investigate the changes in calcitonin gene-related peptide(CGRP) within the adrenal glands medulla and cortex of the rat during early post burn period and the effect of CGRP on function of adrenal gland of burned rats.


METHODS
The rats were randomly divided into two groups: control and burned. The distribution density of CGRP containing nerve fibers and cells in medulla of adrenal gland were determined at different timepoints post burn.


RESULTS
1. The CGRP-containing nerve fibers were distributed in capsule, cortex and medulla. CGRP-containing nerve fibers were associated with CGRP immunoreactive cell in medulla of adrenal glands. 2. Distribution density of CGRP-containing nerve fiber was decreased, but distribution density of CGRP-containing cells in medulla increased.


CONCLUSIONS
CGRP may affect function of the adrenal gland of burned rats.
Wang
B
B
Department of Burn, Xijing Hospital of Fourth Military Medical University, Xi'an 710032.
Chen
B
B
Hu
D
D
D000302:Adrenal Cortex / Q000294:innervation / Q000378:metabolism / Q000503:physiopathology; D000311:Adrenal Glands / Q000294:innervation / Q000378:metabolism* / Q000503:physiopathology; D000313:Adrenal Medulla / Q000294:innervation / Q000378:metabolism / Q000503:physiopathology; D000818:Animals; D002056:Burns / Q000378:metabolism* / Q000503:physiopathology; D015740:Calcitonin Gene-Related Peptide / Q000378:metabolism*; D008297:Male; D009412:Nerve Fibers / Q000378:metabolism*; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
D015740:Calcitonin Gene-Related Peptide