[Effect of stimulating the peripheral endings of transected dorsal root on discharges of neighbouring dorsal root in rats].
The dorsal roots (DR) of L2-L3 segments on the left side in anesthetized rats (n = 28) were exposed and transected. After stimulating the peripheral endings of L2 DR with a train of square waves (0.8-1.2 mA, 100 Hz, 0.5 ms) for 2 s, the discharges at the distal end of transected L3 DR were recorded for 120 s. We found that the mean discharge frequency (MDF) of L3 DR was gradually increased with L2 DR stimulation. Time course analysis showed that the increase in MDF was linearly correlative to the number of stimuli, as well as to the levels of spontaneous discharge of L3 DR. The above results suggest that the transegmental information transmission between peripheral endings of primary sensory neurons may occur through a chemical non-synaptic way.
Zhang
Y
Y
Department of Neurobiology, Tongji Medical University, Wuhan 430030.
Deng
Y P
YP
Guan
X M
XM
D000818:Animals; D004558:Electric Stimulation; D004594:Electrophysiology; D005260:Female; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D011984:Sensory Receptor Cells / Q000502:physiology*; D013126:Spinal Nerve Roots / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology