title: [Thromboembolic complications related to the use of bone cement in hip arthroplasty--pathogenesis and prophylaxis].
abstract: BACKGROUND
  Cemented total hip arthroplasty (THA) has to be considered a high-risk procedure with respect to cardiovascular complications. The insertion of cement and prosthesis may lead to intravasation of fat and bone marrow into the circulation.
  
  
  METHODS
  This article represents a review on the relevant literature about thromboembolic complications associated with the use of bone cement in THA.
  
  
  CONCLUSIONS
  The method of canal preparation and lavage is of paramount importance to reduce the potential embolic load. Additionally, thorough cleaning of the intramedullary cavity (using jet lavage) improves the cement penetration into the bone and increases the shear strength of the bone-cement interface. Modern cementing techniques include the use of high pulsatile lavage, a cement restrictor and cement pressurization. With the application of these techniques a sufficient drainage of the medullary canal should be guaranteed to minimise the risk for thromboembolic complications. During the insertion of cementless implants the intravasation of embolic material seems to be less, but it is likewise possible to have a thromboembolic complication during cementless THA. However, it is not justified as a consequence to use the thromboembolic risk as the main indication for implant choice, in particular as the overall risk of a serious fatal complication is low.
authors.affiliation: Abteilung Orthopädie I, Orthopädische Universitätsklinik Heidelberg.
authors.forename: C
authors.initials: C
authors.lastname: Heisel
authors.forename: M
authors.initials: M
authors.lastname: Clarius
authors.forename: U
authors.initials: U
authors.lastname: Schneider
authors.forename: S J
authors.initials: SJ
authors.lastname: Breusch
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D001843:Bone Cements / Q000009:adverse effects*; D004620:Embolism, Fat / Q000139:chemically induced* / Q000517:prevention & control; D006801:Humans; D012307:Risk Factors; D007507:Therapeutic Irrigation; D013923:Thromboembolism / Q000139:chemically induced* / Q000517:prevention & control
chemical_list: D001843:Bone Cements