Navigating gene expression using microarrays--a technology review.
Parallel quantification of large numbers of messenger RNA transcripts using microarray technology promises to provide detailed insight into cellular processes involved in the regulation of gene expression. This should allow new understanding of signalling networks that operate in the cell and of the molecular basis and classification of disease. But can the technology deliver such far-reaching promises?
Schulze
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Signal Transduction Laboratory, Imperial Cancer Research Fund, 44Lincoln's Inn Fields, London WC2A 3PX, UK. schulze@icrf.icnet.uk
Downward
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J
D000818:Animals; D016000:Cluster Analysis; D005786:Gene Expression Regulation / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics
D012333:RNA, Messenger