title: Another feature of TURP syndrome: hyperglycaemia and lactic acidosis caused by massive absorption of sorbitol.
abstract: Endoscopic transurethral resection of the prostate (TURP) can be complicated by absorption of a large volume of irrigation fluid. The clinical features of this complication are referred as the TURP syndrome. We report a case where hyperglycaemia and lactic acidosis complicated the TURP syndrome caused by the massive absorption (approximately 15 litres) of a sorbitol- mannitol irrigation solution. The proposed mechanism is a type B lactic acidosis related to the metabolism of sorbitol.
authors.affiliation: Department of Anesthesia, Centre hospitalier affilié universitaire de Québec, Hôpital Enfant-Jésus, Laval University, 1401, 18 Rue, Québec, PQ, G1J 1Z4 Canada.
authors.forename: C A
authors.initials: CA
authors.lastname: Trépanier
authors.forename: M R
authors.initials: MR
authors.lastname: Lessard
authors.forename: J
authors.initials: J
authors.lastname: Brochu
authors.forename: G
authors.initials: G
authors.lastname: Turcotte
mesh_terms: D000140:Acidosis, Lactic / Q000209:etiology*; D000368:Aged; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology*; D007430:Intraoperative Care / Q000009:adverse effects; D008297:Male; D010592:Pharmaceutic Aids / Q000009:adverse effects*; D013012:Sorbitol / Q000009:adverse effects*; D013577:Syndrome; D007507:Therapeutic Irrigation / Q000009:adverse effects; D020728:Transurethral Resection of Prostate / Q000009:adverse effects*
chemical_list: D010592:Pharmaceutic Aids; D013012:Sorbitol