title: [3D FSPGR (fast spoiled gradient echo) magnetic resonance imaging in the diagnosis of focal cortical dysplasia in children].
abstract: Small dysplastic lesions of the cerebral cortex are often missed by conventional MRI methods. The identification of subtle structural abnormalities by traditional multiplanar rectilinear slices is often limited by the complex convolutional pattern of the brain. We used a method of FSPGR (fast spoiled gradient-echo) of three-dimensional MRI data that improves the anatomical display of the sulcal structure of the hemispheric convexities. It also reduces the asymmetric sampling of gray-white matter that may lead to false-positive results. We present 5 from 12 patients with dysplastic cortical lesions in whom conventional two-dimensional and three-dimensional MRI with multiplanar reformatting was initially considered normal. Subsequent studies using 3D FSPGR identified various types of focal cortical dysplasia in all. These results indicate that an increase in the detection of subtle focal dysplastic lesions may be accomplished when one improves the anatomical display of the brain sulcal structure by performing 3D FSPGR.
authors.affiliation: N. A. Setshenov Moscow Medical Academy.
authors.forename: A A
authors.initials: AA
authors.lastname: Alikhanov
authors.forename: V E
authors.initials: VE
authors.lastname: Sinitsyn
authors.forename: E M
authors.initials: EM
authors.lastname: Perepelova
authors.forename: K Iu
authors.initials: KIu
authors.lastname: Mukhin
authors.forename: A A
authors.initials: AA
authors.lastname: Demushkina
authors.forename: M O
authors.initials: MO
authors.lastname: Omarova
authors.forename: S V
authors.initials: SV
authors.lastname: Piliia
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002540:Cerebral Cortex / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male