title: Adult respiratory distress syndrome among blunt and penetrating trauma patients: demographics, mortality, and resource utilization over 8 years.
abstract: OBJECTIVE
  The purpose of this study was to compare demographics, resources used, and mortality rates among a subset of trauma patients (blunt versus penetrating) who developed adult respiratory distress syndrome (ARDS) and over two time periods, 8 years apart.
  
  
  METHODS
  This retrospective observational study was based on an analysis of the computerized Trauma Registry of the Shock Trauma Center of the University of Maryland Medical Systems. All trauma patients with ARDS admitted to a 48-bed trauma intensive care unit (ICU) at a Level I Trauma Center during two time periods of 3 consecutive years each were considered: from January 1, 1985, to December 31, 1987 (G1), and January 1, 1993, to December 31, 1995 (G2). Data were collected in the two time periods on demographics, severity (Revised Trauma Score), injury-admission delay time, first 24-hour transfusion fluids and blood, septic and organ system failure complications, life-support techniques, ICU mortality, and length of stay (LOS). The independent variables were the age, type of trauma, severity scores, transport time, fluid therapy, infectious and organ system failure complications, and life-support techniques. The dependent variable was ICU mortality.
  
  
  RESULTS
  A total of 1,108 patients satisfied the entry criteria, 486 in period G1 and 552 in period G2; 929 (89.5%) suffered blunt trauma and 109 (10.5%) penetrating trauma. Mean age was lower for the penetrating trauma populations. There were no significant differences in ICU mortality between the blunt and penetrating trauma patients with ARDS. A significant decrease in ICU mortality was observed between the time periods studied among both blunt (29.5% vs. 21.7%, P <.001) and penetrating trauma patients (25.7% vs. 18.9%, P <.001). A similar rate of renal, hematologic, and cardiovascular organ system failure was observed for both blunt and penetrating trauma patients. Resource utilization measured by ICU LOS and time on mechanical ventilation was also similar in the two groups. The multivariate analysis showed that ICU mortality was related to age, RTS-measured severity, and time period (G1 mortality 1.68-fold that in G2). Renal and hematologic failures entered a second analysis, replacing the time period variable (G2).
  
  
  CONCLUSIONS
  ARDS in patients with blunt and penetrating trauma showed similar trends in ICU mortality, complications, and resource utilization. The ARDS mortality rate decreased over the time period studied in both blunt and penetrating trauma.
authors.affiliation: Departments of Critical Care and Trauma Surgery, R. Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore MD, USA.
authors.forename: P
authors.initials: P
authors.lastname: Navarrete-Navarro
authors.forename: A
authors.initials: A
authors.lastname: Rodriguez
authors.forename: N
authors.initials: N
authors.lastname: Reynolds
authors.forename: R
authors.initials: R
authors.lastname: West
authors.forename: R
authors.initials: R
authors.lastname: Rivera
authors.forename: T
authors.initials: T
authors.lastname: Scalea
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D006295:Health Resources / Q000706:statistics & numerical data*; D017052:Hospital Mortality; D006801:Humans; D007902:Length of Stay; D008396:Maryland / Q000453:epidemiology; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000401:mortality* / Q000628:therapy; D012189:Retrospective Studies; D014949:Wounds, Nonpenetrating / Q000150:complications / Q000401:mortality*; D014950:Wounds, Penetrating / Q000150:complications / Q000401:mortality*