[Observation on effect of shenmai injection in treating patients of congestive heart failure].
OBJECTIVE
To observe the clinical therapeutic effect of Shenmai Injection (SMI) in treating patients of congestive heart failure.


METHODS
Effect of 16 cases treated with SMI or potassium magnesium aspartate was observed by randomized crossover method and compared.


RESULTS
By using SMI for 2 weeks, patients' left ventricular ejective fraction (LVEF) could be increased from 29.5 +/- 9.0 to 36.6 +/- 10.2 (P < 0.05), the heart function of 68.75% patients was improved, no side effects or toxicity was observed. Potassium magnesium asparate could improve heart function in 37.50% patients only but with no effect on LVEF.


CONCLUSIONS
SMI is an effective and safe therapy in treating patients with congestive heart failure.
Liu
Z
Z
Division of Cardio-Pulmonary Circulation Funai Hospital, Chinese Academy of Medical Sciences, Beijing 100037.
Cheng
X
X
Zhang
C
C
D000328:Adult; D000368:Aged; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D013318:Stroke Volume / Q000187:drug effects
D004365:Drugs, Chinese Herbal