Intestinal microsporidiosis in HIV-infected children with acute and chronic diarrhea.
A prospective study of intestinal microsporidiosis in HIV-positive children was conducted at the Queen Sirikit National Institute of Child Health and Phramongkutklao Hospital, Bangkok, Thailand. Hospitalized HIV-positive children with and without diarrhea were enrolled in this study. Microsporidial spores identified by calcofluor fluorescent and gram-chromotrope stain were confirmed by electron microscopy. As well as Cryptosporidium parvum, Microsporidia was the most common protozoa found in the present study, each was 7.1%. Microsporidia was significantly more common in those who had diarrhea. Intestinal microsporidiosis was found in HIV-positive children with both acute and chronic diarrhea. This study emphasizes the importance of Microsporidia in HIV-infected children. Early detection of microsporidia could be of benefit for the patients, since the infection is treatable.
Leelayoova
S
S
Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, Thailand.
Vithayasai
N
N
Watanaveeradej
V
V
Chotpitayasunondh
T
T
Therapong
V
V
Naaglor
T
T
Mungthin
M
M
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000503:physiopathology; D000208:Acute Disease; D002908:Chronic Disease; D003967:Diarrhea / Q000150:complications* / Q000503:physiopathology; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D007223:Infant; D007411:Intestinal Diseases, Parasitic / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008854:Microscopy, Electron; D021861:Microsporidia, Unclassified / Q000302:isolation & purification / Q000502:physiology / Q000648:ultrastructure; D016881:Microsporidiosis / Q000150:complications* / Q000503:physiopathology; D013170:Spores / Q000302:isolation & purification / Q000648:ultrastructure