title: [MRI finding of CNS cryptococcosis in an HIV-positive patient].
abstract: We report an HIV-positive patient with CNS cryptococcosis, diagnosis of which was based on detection of Cryptococcus neoformans by Indian ink staining and culture of CSF. MRI displayed dilated Virchow-Robin space in bilateral basal ganglia which were hypointense on T1-weighted images, hyperintense on T2-weighted images, and enhanced by gadolinium administration. In addition cryptococcoma in the cerebellum was observed by MRI. This finding may suggest a progression from cryptococcal meningitis to intraparenchymal invasion, accompanied with breakdown of the blood brain barrier.
authors.affiliation: Cerebrovascular Center, Ebina East General Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Mandokoro
authors.forename: K
authors.initials: K
authors.lastname: Tokuoka
authors.forename: Y
authors.initials: Y
authors.lastname: Ohnuki
authors.forename: S
authors.initials: S
authors.lastname: Takizawa
authors.forename: Y
authors.initials: Y
authors.lastname: Shinohara
mesh_terms: D000328:Adult; D001479:Basal Ganglia / Q000473:pathology; D003453:Cryptococcosis / Q000175:diagnosis* / Q000209:etiology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000209:etiology