title: [Familial articular chondrocalcinosis: study of an Alsatian family].
abstract: Familial articular chondrocalcinosis is a chronic articular disease characterized by acute intermittent attacks of arthritis, presence of calcium pyrophosphate dihydrate crystal in synovial fluid, cartilage and periarticular soft tissue and by x rays calcium deposition in articular cartilage. A family originating from Alsace, with an autosomal dominant transmission has been studied. As in English and Argentinean families, a linkage to the short arm of chromosome 5p has been found. These results suggest that a defective gene at this location may be related to the chondrocalcinosis in these families.
authors.affiliation: L'UMR 7561 CNRS-UHP Physiopathologie et Pharmacologie Articulaires, Faculté de Médecine, BP 184, 54505 Vandoeuvre-les-Nancy.
authors.forename: P
authors.initials: P
authors.lastname: Netter
authors.forename: D
authors.initials: D
authors.lastname: Loeuille
authors.forename: J Y
authors.initials: JY
authors.lastname: Jouzeau
authors.forename: P
authors.initials: P
authors.lastname: Gillet
authors.forename: J
authors.initials: J
authors.lastname: Peterschmitt
authors.forename: J
authors.initials: J
authors.lastname: Pourel
authors.forename: A
authors.initials: A
authors.lastname: Gaucher
mesh_terms: D000328:Adult; D002805:Chondrocalcinosis / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D005602:France; D006801:Humans