Fast three-dimensional sodium imaging of human brain.
A three-dimensional sodium imaging technique with a minimum echo time of 0.9 ms is described in a 2.0 Tesla whole-body system. The relaxation behaviour in vivo of sodium was analysed: a fast T(2)(*) relaxation component between 1.2 and 1.6 ms and a slow T(2)(*) relaxation component between 7.1 ms and 8.4 ms were quantified in brain tissue of three volunteers. Three-dimensional sodium images of the human brain were acquired in 8.5 min with a resolution of 4.7 x 4.7 x 10 mm (0.2 cc voxel size) and a signal-to-noise ratio of 20 in brain tissue and 30 in cerebrospinal fluid.
Köhler
S
S
Lehrstuhl für Experimentelle Physik V, Physikalisches Institut, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany. sakoehler@physik.uni-wuerzburg.de
Preibisch
C
C
Nittka
M
M
Haase
A
A
D001703:Biophysics / Q000379:methods*; D001921:Brain / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012964:Sodium; D013997:Time Factors
D012964:Sodium