[Immediate results of treatment of patients with rectal cancer using neoadjuvant chemotherapy and radiotherapy].
Immediate results of treatment of 103 patients with cancer of the proximal part of rectum were analyzed. In 54 patients there was applied in complex of treatment neoadjuvant chemotherapy: intraabdominal infusion of fluorouracil (0.6 g/m2, 4-6 g dose for the course) in combination with gamma-therapy (20 Gr) with subsequent infusion of cisplatinum (60 mg/m2), to 49 patients only surgical treatment was done. Complex treatment, conducted according to the proposed method, didn't worsen the conditions of the operation performance, didn't increase intraoperative blood loss and frequency of intra- and postoperative complications, didn't change their structure and didn't worsen the immediate result of operation.
Vinnyk
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IuO
Chybisov
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LP
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000532:radiotherapy*; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D012189:Retrospective Studies; D016896:Treatment Outcome