[Radioimmunodetection in the diagnosis of trophoblastic disease].
OBJECTIVE
To study the efficiency of radioimmunodetection (RID) to locate the loci of trophoblastic disease.


METHODS
24 RIDs were performed with 131I labeled mouse anti-hCG monoclonal antibodies on 21 patients with trophoblastic disease.


RESULTS
Of 24 RIDs performed, 13 were positive, including one false positive; 11 were negative, including two false negative. The sensitivity of RID was 85.7%, the specificity was 90.0%, the accuracy was 87.5%. In 8 patients who underwent operations after RID, the findings of RID were in accordance with the pathologic and immunohistologic findings.


CONCLUSIONS
RID is an efficient imaging method for trophoblastic disease. In some cases, RID showed its value as a functional diagnostic method.
Wan
X
X
Peking Union Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730.
Yang
X
X
Song
H
H
D000328:Adult; D000911:Antibodies, Monoclonal; D002822:Choriocarcinoma / Q000000981:diagnostic imaging*; D006063:Chorionic Gonadotropin / Q000276:immunology*; D005260:Female; D006801:Humans; D002820:Hydatidiform Mole, Invasive / Q000000981:diagnostic imaging; D007457:Iodine Radioisotopes; D011247:Pregnancy; D016719:Radioimmunodetection; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging*
D000911:Antibodies, Monoclonal; D006063:Chorionic Gonadotropin; D007457:Iodine Radioisotopes