Retinopathy, hematuria, and diabetic nephropathy.
We have retrospectively analyzed the incidence of diabetic nephropathy in 21 diabetic patients who underwent renal biopsy between 1985 and 1995 for microscopic hematuria and/or proteinuria >2.5 g/day without retinopathy. Diabetic nephropathy was observed in 13 of 21 patients (62%). 50% of our patients with diabetic nephropathy had hematuria, the incidence being higher in type I as compared with type II diabetic patients (30 vs. 20%). Diabetic nephropathy without retinopathy but with hematuria was noted in 5 of 13 patients, and diabetic nephropathy without retinopathy and hematuria was also noted in 5 of 13 patients. We suggest from our retrospective analysis that renal-retinal diabetic syndrome really exists.
Izzedine
H
H
Department of Nephrology, Pitié-Salpêtrière Hospital, Paris, France. hassan.izzedine@psl.ap-hop-paris.fr
Fongoro
S
S
Pajot
O
O
Beaufils
H
H
Deray
G
G
D000328:Adult; D001706:Biopsy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003928:Diabetic Nephropathies / Q000209:etiology* / Q000473:pathology; D005260:Female; D006417:Hematuria / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D011507:Proteinuria / Q000473:pathology; D012189:Retrospective Studies