[A case of peculiar type of post-encephalitic/encephalopathic epilepsy: efficacy of bromide in the control of intractable seizures].
A 5-year-old boy with a peculiar type of post-encephalitic/encephalopathic epilepsy is reported. He had been healthy showing normal development before its onset. Five days after the onset of an upper respiratory infection, he had a severe generalized seizure, that evolved into intractable seizures. They were highly resistant to almost all anticonvulsants and occasionally resulted in status epilepticus. High-dose phenobarbital therapy successfully controlled the convulsions, but was discontinued because of drug-induced aplastic anemia. Alternative bromide therapy was markedly effective in controlling the seizures.
Takusa
Y
Y
Department of Pediatrics, Shimane Medical University, Izumo, Shimane.
Hori
D
D
Saito
K
K
Kanai
R
R
Sejima
H
H
Kimura
M
M
Kishi
K
K
Yamaguchi
S
S
D001965:Bromides / Q000627:therapeutic use*; D002675:Child, Preschool; D004660:Encephalitis / Q000150:complications*; D004827:Epilepsy / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D008297:Male; D017680:Potassium Compounds / Q000627:therapeutic use*
D001965:Bromides; D017680:Potassium Compounds; C039004:potassium bromide