Regulation of oxygen consumption at exercise onset: is it really controversial?
The conflicting hypotheses on the limiting factors for skeletal muscle VO2 on-kinetics might be reconciled in a unifying scenario. Under "normal" conditions, during transitions to moderate intensity exercise, the limiting factor appears to be an inertia of oxidative metabolism. During transitions to exercise of higher metabolic intensity, O2 delivery could play a relatively minor but significant role as a limiting factor.
Grassi
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Department of Sciences and Biomedical Technologies, School of Medicine, University of Milano, Italy. Bruno.Grassi@unimi.it
D015308:Anaerobic Threshold / Q000502:physiology; D000818:Animals; D019069:Cell Respiration; D004285:Dogs; D015444:Exercise / Q000502:physiology*; D025461:Feedback, Physiological / Q000502:physiology; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000737:chemistry / Q000378:metabolism*; D009211:Myoglobin / Q000737:chemistry; D010085:Oxidative Phosphorylation; D010100:Oxygen / Q000032:analysis / Q000493:pharmacokinetics; D010101:Oxygen Consumption / Q000502:physiology*; D010806:Physical Education and Training / Q000379:methods; D013997:Time Factors; D014018:Tissue Distribution
D009211:Myoglobin; D010100:Oxygen