[Metadoxyl in combined treatment of alcohol damage to the liver].
20 patients of the study group and 12 control patients with alcoholic liver lesion received i.v. glucose and vitamins solution, lipotropic drugs. In addition, patients of the study group were given metadoxyl tablets (Baldacchi, Italy) in a dose 1500-2000 mg/day per os for 30 days. Before and after the treatment the patients underwent clinical examination, biochemical tests, ultrasonography, scintigraphy. It was found that metadoxyl stimulates normalization of liver function, is well tolerated, produced no side effects, holds perspectives for prevention and delay of hepatic cirrhosis.
Vedrova
N N
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Gnezdilova
N Iu
NIu
D000427:Alcohol Deterrents / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011736:Pyridoxine / Q000008:administration & dosage / Q000627:therapeutic use*; D011761:Pyrrolidonecarboxylic Acid / Q000008:administration & dosage / Q000627:therapeutic use*
D000427:Alcohol Deterrents; D004338:Drug Combinations; C037845:metadoxine; D011736:Pyridoxine; D011761:Pyrrolidonecarboxylic Acid