Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5.
Archer
S L
SL
Vascular Biology Group, Department of Medicine, Division of Cardiology, University of Alberta, Alberta, Canada. sarcher@cha.ab.ca
London
B
B
Hampl
V
V
Wu
X
X
Nsair
A
A
Puttagunta
L
L
Hashimoto
K
K
Waite
R E
RE
Michelakis
E D
ED
D020413:3' Untranslated Regions; D015761:4-Aminopyridine / Q000494:pharmacology; D020121:5' Untranslated Regions; D000818:Animals; D004351:Drug Resistance / Q000235:genetics; D004553:Electric Conductivity; D018390:Gene Targeting; D000860:Hypoxia / Q000503:physiopathology*; D051666:Kv1.5 Potassium Channel; D008168:Lung / Q000098:blood supply*; D008564:Membrane Potentials; D051379:Mice; D018345:Mice, Knockout; D009131:Muscle, Smooth, Vascular / Q000737:chemistry; D009355:Neomycin; D015221:Potassium Channels / Q000172:deficiency* / Q000235:genetics / Q000502:physiology; D024642:Potassium Channels, Voltage-Gated; D011651:Pulmonary Artery; D012333:RNA, Messenger / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014661:Vasoconstriction
D020413:3' Untranslated Regions; D020121:5' Untranslated Regions; C496982:Kcna5 protein, mouse; D051666:Kv1.5 Potassium Channel; D015221:Potassium Channels; D024642:Potassium Channels, Voltage-Gated; D012333:RNA, Messenger; D015761:4-Aminopyridine; D009355:Neomycin