title: [Histologic and histochemical studies on the temporomandibular articular disc in young growing rats after functional mandibular advancements].
abstract: The purpose of these studies was to detect the patterns of the changes in the site of temporomandibular articular disc in the young growing SD rats after the functional protrusive appliance inserted with histologic and histochemical methods. The results showed that collagen fibres were dense, roughly paralleled linked especially anterioposteriorly after the mandible protruded functionally, chondrocytes and gycosaminoglycans contents increased apparently in the posterior band of the discs. The adaptive remodeling of the discs might be the results of the pressure of the condyle on the discs and the lateral pterygoid muscle to it. The remodeling growth of the discs were coordinate and adaptive with the proliferative changes of the condylar cartilage after the mandible protruded functionally. No pathological changes were found in the rat articular discs.
authors.affiliation: Department of Orthodontics, College of Stomatology, West China University of Medical Sciences, China.
authors.forename: D
authors.initials: D
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Luo
mesh_terms: D000818:Animals; D019902:Chondrocytes / Q000473:pathology; D003094:Collagen / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000378:metabolism*; D008297:Male; D019186:Mandibular Advancement; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D019224:Temporomandibular Joint Disc / Q000254:growth & development / Q000378:metabolism / Q000473:pathology
chemical_list: D006025:Glycosaminoglycans; D003094:Collagen