[A study of therapeutic efficacy of Koukangning gargle in the treatment of oral mucositis].
A study of therapeutic efficacy was carried out in 118 patients with oral mucositis (recurrent oral aphthous ulceration, erosive lichen planus, herptic stomatitis and infectious oral mucosal hematoma) at random. As a topical medication, Koukangning gargle was applied to 59 patients of the experimental group, 29 patients of the control group 1 applied Dobell's solution to rinse their mouths, and 30 patients of the control group 2 applied Koutai solution. A satisfactory result was observed in the experimental group, its effectiveness and effective rates rose more than those of control group 1 at both treatments for 3 days and 6 days. Between the two groups, there were markedly significant difference (P < 0.005, P < 0.01, P < 0.005, P < 0.005). Koukangning gargle was nontoxic and no side-effects in the clinical tests. Its efficacy was no significant difference compared with the control group 2. Experimental study demonstrates that it possesses anti-inflamation effect and excellent antibiotic effect, therefore it is a new gargle for rinse mouth combined traditional Chinese medicine with Western medicine.
Zeng
G
G
College of Stomatology, West China University of Medical Sciences.
Li
B
B
Zhang
W
W
D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D002735:Chlorophyllides / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D017676:Lichen Planus, Oral / Q000188:drug therapy*; D016037:Single-Blind Method; D013281:Stomatitis, Aphthous / Q000188:drug therapy*
D000891:Anti-Infective Agents, Local; D002735:Chlorophyllides; C007020:chlorophyllin