A new type of potent inhibitors of HIV-1 TAR RNA-Tat peptide binding by zinc(II)-macrocyclic tetraamine complexes.
Kikuta
E
E
Department of Medicinal Chemistry Faculty of Medicine, Hiroshima University Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan.
Aoki
S
S
Kimura
E
E
D000074183:ATPases Associated with Diverse Cellular Activities; D000595:Amino Acid Sequence; D019380:Anti-HIV Agents / Q000737:chemistry* / Q000494:pharmacology; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000737:chemistry*; D005029:Ethylenediamines / Q000737:chemistry*; D016325:HIV Long Terminal Repeat / Q000187:drug effects / Q000235:genetics*; D015497:HIV-1; D008969:Molecular Sequence Data; D009942:Organometallic Compounds / Q000737:chemistry* / Q000494:pharmacology; D046988:Proteasome Endopeptidase Complex; D012367:RNA, Viral / Q000737:chemistry* / Q000187:drug effects; D013942:Thymine Nucleotides / Q000737:chemistry; D014500:Uracil Nucleotides / Q000737:chemistry; D015032:Zinc / Q000737:chemistry*
C101432:1,1'-(3-xylenediyl)-bis(1,4,7,10-tetraazacyclodecane); D019380:Anti-HIV Agents; D004268:DNA-Binding Proteins; D005029:Ethylenediamines; D009942:Organometallic Compounds; D012367:RNA, Viral; D013942:Thymine Nucleotides; D014500:Uracil Nucleotides; D046988:Proteasome Endopeptidase Complex; D000074183:ATPases Associated with Diverse Cellular Activities; C064757:PSMC3 protein, human; D015032:Zinc