title: Rhinosporidiosis and peripheral keratitis.
abstract: Report of a case of peripheral keratitis caused by Rhinosporidium seeberi. The patient was seen in a referral practice. Corneal scraping was performed on a middle-aged female patient presenting with peripheral keratitis and progressive nasal obstruction that revealed spores suggestive of rhinosporidiosis. The patient was started on topical amphotericin B 0.15% eye drops. Ear, nose, and throat (ENT) examination showed presence of a polypoid lesion in the left nostril for which a polypectomy was performed. Histopathological examination confirmed rhinosporidiosis. Complete resolution of the keratitis was observed. Topical amphotericin B is an effective drug in the management of this condition. Keratitis secondary to rhinosporidial infection has not been described although occasional patients with limbal and scleral involvement have been reported. Corneal scraping was effective in helping us make a tentative diagnosis.
authors.affiliation: Department of Ophthalmology, Guru Nanak Eye Centre, New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Bhomaj
authors.forename: J C
authors.initials: JC
authors.lastname: Das
authors.forename: Z
authors.initials: Z
authors.lastname: Chaudhuri
authors.forename: R L
authors.initials: RL
authors.lastname: Bansal
authors.forename: P
authors.initials: P
authors.lastname: Sharma
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003315:Cornea / Q000382:microbiology* / Q000473:pathology; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D009883:Ophthalmic Solutions; D012227:Rhinosporidiosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D012228:Rhinosporidium / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents; D009883:Ophthalmic Solutions; D000666:Amphotericin B