title: Perthes' disease in the adolescent.
abstract: We studied the natural history of Perthes' disease in 62 children in whom the onset of symptoms was in adolescence. Three patterns of disease were noted, namely, late-onset pattern, segmental collapse, or destructive with failure of revascularisation. In the late-onset pattern, the disease followed the sequence of healing seen in younger children, but adequate epiphyseal remodelling did not occur. Consequently, the femoral head was never spherical after revascularisation. With segmental collapse, early and irreversible collapse of part of the epiphysis occurred with gross deformation of the femoral head. The destructive pattern was characterised by a failure of revascularisation and repair of the avascular epiphysis. The radiological outcome was poor in all three patterns. The poorest clinical results were found in the destructive type which was frequently associated with incapacitating pain requiring arthrodesis or excision arthroplasty within three years of onset of the disease.
authors.affiliation: Department of Orthopaedics, Kasturba Medical College, Manipal, Karnataka State, India.
authors.forename: B
authors.initials: B
authors.lastname: Joseph
authors.forename: K
authors.initials: K
authors.lastname: Mulpuri
authors.forename: G
authors.initials: G
authors.lastname: Varghese
mesh_terms: D000293:Adolescent; D001174:Arthrodesis; D018450:Disease Progression; D004838:Epiphyses / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D005270:Femur Head / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D007873:Legg-Calve-Perthes Disease / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography; D016896:Treatment Outcome