title: Evaluation of the uterine cavity with magnetic resonance imaging, transvaginal sonography, hysterosonographic examination, and diagnostic hysteroscopy.
abstract: OBJECTIVE
  To evaluate and compare the diagnostic accuracy of magnetic resonance imaging (MRI), transvaginal ultrasonography (TVS), hysterosonographic examination (HSE), and hysteroscopy in the evaluation of the uterine cavity.
  
  
  METHODS
  Independent double-blind study.
  
  
  METHODS
  University medical hospital.
  
  
  METHODS
  One hundred six consecutive premenopausal women who underwent hysterectomy for benign diseases.
  
  
  METHODS
  Results of MRI, TVS, HSE, and hysteroscopy were compared with the results of histopathologic examination at hysterectomy (the gold standard).
  
  
  RESULTS
  The overall sensitivity was MRI 0.76, TVS 0.69, HSE 0.83, and hysteroscopy 0.84. The specificity was MRI 0.92, TVS 0.83, HSE 0.90, and hysteroscopy 0.88 (MRI, HSE, hysteroscopy vs. TVS <0.05). Polyps were missed in 9 of 12 cases at MRI, 7 at TVS, 4 at HSE, and 2 at hysteroscopy (MRI vs. hysteroscopy, and TVS vs. hysteroscopy <0.05). The sensitivity for identification of submucous myomas was MRI 1.0, TVS 0.83, HSE 0.90, and hysteroscopy 0.82; the specificity was MRI 0.91, TVS 0.90, HSE 0.89, and hysteroscopy 0.87 (MRI vs. TVS, and MRI vs. hysteroscopy). Magnetic resonance imaging was significantly more precise than TVS, HSE, and hysteroscopy in determining submucous myoma in-growth (2-way ANOVA <0.05).
  
  
  CONCLUSIONS
  For exclusion of abnormalities in the uterine cavity, MRI, HSE, and hysteroscopy were equally effective and slightly superior to TVS. Magnetic resonance imaging and TVS missed endometrial abnormalities such as polyps, but MRI and HSE were most accurate for the evaluation of submucous myomas, and MRI was superior in evaluation of exact submucous myoma in-growth.
authors.affiliation: Department of Gynecology and Obstetrics, Aarhus University and Aarhus University Hospital, Aarhus, Denmark. hjorth@dadlnet.dk
authors.forename: M
authors.initials: M
authors.lastname: Dueholm
authors.forename: E
authors.initials: E
authors.lastname: Lundorf
authors.forename: E S
authors.initials: ES
authors.lastname: Hansen
authors.forename: S
authors.initials: S
authors.lastname: Ledertoug
authors.forename: F
authors.initials: F
authors.lastname: Olesen
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis / Q000473:pathology; D015907:Hysteroscopy; D008279:Magnetic Resonance Imaging; D009214:Myoma / Q000175:diagnosis / Q000473:pathology; D011127:Polyps / Q000175:diagnosis / Q000473:pathology; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014591:Uterine Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014599:Uterus / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery