title: Coinfecting deer-associated zoonoses: Lyme disease, babesiosis, and ehrlichiosis.
abstract: The heightened worldwide recognition of the health burden of tickborne infection derives largely from the increasing incidence of Lyme disease, human babesiosis, and human granulocytic ehrlichiosis, both individually and in concert. Because these infections share the same rodent reservoir and tick vector hosts, they can be cotransmitted to human hosts. Indeed, human coinfections involving various combinations of these pathogens are common, and some tend to be particularly severe. Diagnostic procedures and clinical management of the resulting disease syndrome is rendered complex by the diversity of pathogens involved and by the unusual diversity and duration of symptoms.
authors.affiliation: Department of Pediatrics, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
authors.forename: C
authors.initials: C
authors.lastname: Thompson
authors.forename: A
authors.initials: A
authors.lastname: Spielman
authors.forename: P J
authors.initials: PJ
authors.lastname: Krause
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001404:Babesiosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D015897:Comorbidity; D003670:Deer / Q000382:microbiology / Q000469:parasitology; D003937:Diagnosis, Differential; D004197:Disease Reservoirs / Q000662:veterinary; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D016873:Ehrlichiosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D008193:Lyme Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D015047:Zoonoses / Q000635:transmission*
chemical_list: D000900:Anti-Bacterial Agents