title: Surgical management of actinic cheilitis.
abstract: OBJECTIVE
  An analysis is made of the etiologic factors underlying actinic cheilitis and of the results obtained following surgical treatment of the disease in a series of 54 patients (32 males and 22 females).
  
  
  METHODS
  The case history was evaluated, along with the triggering factors, histopathological pattern and recurrence of lesions. A cold scalpel vermilionectomy was performed in 41 patients, followed by primary closure of the defect using an oral mucosal flap. The remaining 13 patients were subjected to carbon dioxide laser vermilion ablation.
  
  
  RESULTS
  The history of the patients revealed liver disease associated to alcohol consumption in 35.2% of cases and tobacco smoking in 77.8%. As regards solar exposure, 53.1% of the men referred open-air professional activities, while 100% of the women presented important solar exposure. The most frequent clinical manifestations were bleeding and the presence of leukoplakia patches; pain was reported in only 16% of cases. Over 40% of the patients were asymptomatic. Following treatment, and after a follow-up period of at least 6 months, 90.7% of the subjects showed complete healing. Of the 5 patients reoperated upon, four healed and one evolved towards squamous cell carcinoma.
  
  
  CONCLUSIONS
  Vermilionectomy is the recommended treatment for actinic cheilitis, using either a cold scalpel or carbon dioxide laser. A histological study of the lesion is indicated in all cases to secure early detection of possible malignization. The control of the possible etiologic factors is also essential.
authors.affiliation: Facultad de Odontología de la Universidad de Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Satorres Nieto
authors.forename: J
authors.initials: J
authors.lastname: Gargallo Albiol
authors.forename: C
authors.initials: C
authors.lastname: Gay Escoda
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002245:Carbon Dioxide; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002613:Cheilitis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D007972:Leukoplakia, Oral / Q000503:physiopathology / Q000601:surgery; D008046:Lip / Q000601:surgery; D008048:Lip Neoplasms / Q000473:pathology; D008108:Liver Diseases, Alcoholic / Q000150:complications; D008297:Male; D008875:Middle Aged; D006472:Oral Hemorrhage / Q000503:physiopathology / Q000601:surgery; D017060:Patient Satisfaction; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects; D013472:Sunlight / Q000009:adverse effects; D013524:Surgical Flaps; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D002245:Carbon Dioxide