title: Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17): PPND family. A longitudinal videotape demonstration.
abstract: Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), characterized by an autosomal dominant inheritance pattern, has recently been recognized as a distinct entity that can display a confusingly broad clinical phenotype. The pallido-ponto-nigral degeneration (PPND) variant is the prototypical example of the parkinsonism-predominant pattern of FTDP-17. A longitudinal videotape demonstration of the clinical progression of this entity in a single individual, along with brief videotape segments from three additional affected individuals, is presented in order to facilitate recognition of this disorder.
authors.affiliation: Department of Neurology, Mayo Clinic, Jacksonville, Florida, USA.
authors.forename: Z K
authors.initials: ZK
authors.lastname: Wszolek
authors.forename: R H
authors.initials: RH
authors.lastname: Kardon
authors.forename: E C
authors.initials: EC
authors.lastname: Wolters
authors.forename: R F
authors.initials: RF
authors.lastname: Pfeiffer
mesh_terms: D000328:Adult; D002886:Chromosomes, Human, Pair 17; D003704:Dementia / Q000175:diagnosis / Q000235:genetics*; D005500:Follow-Up Studies; D008040:Genetic Linkage / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D020734:Parkinsonian Disorders / Q000175:diagnosis / Q000235:genetics*; D014743:Videotape Recording