title: Relationship between bone mass density and tensile strength of the skin in women.
abstract: BACKGROUND
  Skin and bone may be affected similarly during the climacteric and during long-term corticotherapy. Little is known about the correlation between the respective alterations in bone mass density (BMD) and tensile strength of the skin.
  
  
  METHODS
  A total of 100 women aged 19-88 years, receiving, or not, hormone replenishment therapy or systemic corticosteroids, were enrolled in the study. Tensile strength of the inner forearm skin was measured using the suction method operated in both the steep and progressive-force application modes. BMD was measured by dual X-ray absorptiometry at the hip, femoral neck and lumbar spine.
  
  
  RESULTS
  Being heterogeneous, the population of volunteers yielded a wide range of BMD and cutaneous tensile strength values. However, significant correlations were found between BMD and tensile skin parameters. In particular, a positive correlation was yielded between the biological elasticity of skin and the BMD of the hip and femoral neck.
  
  
  CONCLUSIONS
  An overall correlation is shown between skin elasticity on a relatively sun-protected area and cortico-trabecular BMD.
authors.affiliation: Department of Dermatopathology, University of Liège, Liège, Belgium. gerald.pierard@ulg.ac.be
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
authors.forename: C
authors.initials: C
authors.lastname: Piérard-Franchimont
authors.forename: S
authors.initials: S
authors.lastname: Vanderplaetsen
authors.forename: N
authors.initials: N
authors.lastname: Franchimont
authors.forename: U
authors.initials: U
authors.lastname: Gaspard
authors.forename: M
authors.initials: M
authors.lastname: Malaise
mesh_terms: D015502:Absorptiometry, Photon; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density / Q000502:physiology*; D004548:Elasticity; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging; D006615:Hip / Q000000981:diagnostic imaging; D020249:Hormone Replacement Therapy; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008875:Middle Aged; D010024:Osteoporosis / Q000188:drug therapy / Q000503:physiopathology; D012867:Skin; D013223:Statistics as Topic; D013718:Tensile Strength / Q000502:physiology*
chemical_list: D000305:Adrenal Cortex Hormones