[Experimental study on therapeutical effect of Chinese medicine on polymyositis in guinea pigs].
OBJECTIVE
To study the therapeutical effects of Radix Bupleuri and Ramulus Cinnamomi on virus polymyositis in guinea pigs.


METHODS
Forty polymyositis guinea pigs induced by Coxsackievirus B1 were divided at random into A(n = 15), B(n = 15), C(n = 10) groups. A, B groups were treated with Radix Bupleuri and Ramulus Cinnamomi respectively. C group received no treatment. Sign, muscle enzyme spectrum and pathological changes were compared.


RESULTS
A and B groups became better. C group showed an aggravating trend (P < 0.05).


CONCLUSIONS
Radix Bupleuri and Ramulus Cinnamomi had therapeutic effect on polymyositis in guinea pigs.
Chu
X
X
Department of Neurology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029.
Hou
X
X
D000818:Animals; D003384:Coxsackievirus Infections / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D029822:Enterovirus B, Human; D005260:Female; D006168:Guinea Pigs; D008297:Male; D017285:Polymyositis / Q000188:drug therapy* / Q000821:virology; D011897:Random Allocation
D004365:Drugs, Chinese Herbal