title: Impact of a limited fluoroquinolone reimbursement policy on antimicrobial prescription claims.
abstract: OBJECTIVE
  To examine the influence on administrative pharmacy claims of a policy that limited the reimbursement of the fluoroquinolones and other antimicrobials in the senior population within Nova Scotia, Canada.
  
  
  METHODS
  The administrative claims database of the Nova Scotia Seniors' Pharmacare Program was used to identify all prescription claims for orally administered antibiotics and urinary antiinfectives. The number of beneficiaries receiving antimicrobials and the number, duration, and cost of prescriptions for antimicrobials were measured monthly. Descriptive time-series plots were used to compare antimicrobial use for two 12-month periods before the institution of the policy (December 1, 1994-November 30, 1995, and December 1, 1995-November 30, 1996) and the 12 months after the policy took effect (January 1, 1997-December 31, 1997).
  
  
  RESULTS
  Following the implementation of the fluoroquinolone reimbursement policy, the number of patients using antimicrobials decreased by 2.2% and the number of prescriptions for antimicrobials decreased by 3.4%. Fluoroquinolone prescriptions decreased by 80.2%; prescriptions for sulfonamides and trimethoprim increased by 34.9%, cephalosporins by 17.0%, and macrolides and lincosamides by 16.5%. The only prescription duration to change was the fluoroquinolones, which increased by 25%. The average cost per antimicrobial user/year decreased from $35.24 during prepolicy period 2 to $27.51 during the postpolicy period.
  
  
  CONCLUSIONS
  Prescription claims for fluoroquinolones in seniors decreased following the introduction of the policy. Total antimicrobial use also decreased, although this may be related to other factors. The effect of this policy change on patient outcomes requires further study.
authors.affiliation: Department of Family Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. mary.maccara@dal.ca
authors.forename: M E
authors.initials: ME
authors.lastname: MacCara
authors.forename: I S
authors.initials: IS
authors.lastname: Sketris
authors.forename: D G
authors.initials: DG
authors.lastname: Comeau
authors.forename: S D
authors.initials: SD
authors.lastname: Weerasinghe
mesh_terms: D000368:Aged; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000191:economics*; D024841:Fluoroquinolones; D006299:Health Services for the Aged / Q000191:economics*; D006801:Humans; D007349:Insurance, Health, Reimbursement / Q000331:legislation & jurisprudence* / Q000706:statistics & numerical data; D007356:Insurance, Pharmaceutical Services / Q000191:economics*; D009674:Nova Scotia
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones