title: Sequence polymorphisms, allelic expression status and chromosome locations of the chicken IGF2 and MPR1 genes.
abstract: By screening 26 chicken breeds and lines, DNA polymorphisms were identified in the IGF2 and MPR1 genes, of which mammalian homologues are parentally imprinted, and the GAPD gene, a housekeeping control. Using the polymorphisms as genetic markers, we found that all three genes are expressed biallelically in embryonic tissues. IGF2 and MPR1 were mapped on chicken chromosomes 5 and 3, respectively, by fluorescence in situ hybridization, demonstrating conserved linkage homology between mammals and birds.
authors.affiliation: Division of Human Genetics, National Institute of Genetics, Graduate University for Advanced Studies, 1-111 Yata, Mishima 411-8540, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yokomine
authors.forename: A
authors.initials: A
authors.lastname: Kuroiwa
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Tsudzuki
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuda
authors.forename: H
authors.initials: H
authors.lastname: Sasaki
mesh_terms: D000483:Alleles; D000818:Animals; D001483:Base Sequence; D001947:Breeding; D018797:Cell Cycle Proteins / Q000235:genetics*; D002642:Chick Embryo; D002645:Chickens / Q000235:genetics*; D017124:Conserved Sequence / Q000235:genetics; D010450:Endopeptidases; D005260:Female; D020869:Gene Expression Profiling; D018507:Gene Expression Regulation, Developmental; D018392:Genomic Imprinting / Q000235:genetics; D017404:In Situ Hybridization, Fluorescence; D007335:Insulin-Like Growth Factor II / Q000235:genetics*; D008297:Male; D020161:Physical Chromosome Mapping; D011110:Polymorphism, Genetic / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics*
chemical_list: D018797:Cell Cycle Proteins; D012333:RNA, Messenger; C115451:RPN11 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D007335:Insulin-Like Growth Factor II; D010450:Endopeptidases