Does lowering plasma homocysteine reduce vascular disease risk?
A recent study indicates that lowering homocysteine with folic acid and vitamin B6 significantly reduces the incidence of abnormal exercise electrocardiography tests and thus decreases the risk of atherosclerotic disease. Questions about study design and sample size, however, suggest that this conclusion may be premature.
Miller
J W
JW
University of California, Davis, Medical Center, Department of Medical Pathology, Sacramento 95817, USA.
D005492:Folic Acid / Q000627:therapeutic use; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D020138:Hyperhomocysteinemia / Q000150:complications / Q000188:drug therapy*; D011736:Pyridoxine / Q000627:therapeutic use; D012307:Risk Factors; D014652:Vascular Diseases / Q000209:etiology* / Q000517:prevention & control*
D006710:Homocysteine; D005492:Folic Acid; D011736:Pyridoxine