[Nephrotic syndrome and anasarca status, secondary to treatment with tiopronin in a case of cystinuria].
OBJECTIVE
To describe a case of cystinuria treated with tiopronin that produced the nephrotic syndrome.


RESULTS
A case of nephrotic syndrome with ascites and heart failure in a patient who had received tiopronin for the treatment of cystinuria is presented. Cystinuria as a rare cause of kidney stones is analyzed. The clinical features, diagnosis and the side effects of treatment with tiopronin are discussed. The patient recovered after withdrawal of the drug.


CONCLUSIONS
It must be emphasized that patients treated with tiopronin should be screened for proteinuria.
Alvarez Navascués
R
R
Servicio de Nefrología II, Hospital Central de Asturias, C/ Julian Claveria s/n 33006 Oviedo, Asturias, España.
Vidau Argüelles
P
P
Rodríguez Suarez
C
C
Herrera Pérez de Villar
J
J
Suarez Heiva
M
M
D000328:Adult; D001201:Ascites / Q000139:chemically induced*; D003555:Cystinuria / Q000188:drug therapy*; D004487:Edema / Q000139:chemically induced*; D005260:Female; D006801:Humans; D009404:Nephrotic Syndrome / Q000139:chemically induced*; D008625:Tiopronin / Q000009:adverse effects*
D008625:Tiopronin