Autoimmune disease: why and where it occurs.
Autoimmune disease is controlled by genetic and environmental factors. Both of these affect susceptibility to autoimmunity at three levels: the overall reactivity of the immune system, the specific antigen and its presentation, and the target issue.
Marrack
P
P
Howard Hughes Medical Institute, University of Colorado Health Sciences Center, Denver, Colorado, USA. marrackp@njc.org
Kappler
J
J
Kotzin
B L
BL
D000941:Antigens / Q000276:immunology; D001327:Autoimmune Diseases / Q000209:etiology* / Q000235:genetics / Q000276:immunology; D002874:Chromosome Mapping; D003429:Cross Reactions; D006801:Humans; D008954:Models, Biological
D000941:Antigens