title: OR-1--a mixture of esters of glyceric acid produced by Penicillium funiculosum and its antitrypsin activity.
abstract: A mixture of related metabolites (denoted OR-1) was isolated from the fermentation broth of Penicillium funiculosum together with mitorubrinic acid. Structurally OR-1 is glyceric acid esterified with C14-C18 fatty acids. Steady-state studies revealed that OR-1 behaved like an uncompetitive trypsin inhibitor with Ki 17.6 mumol/L.
authors.affiliation: Department of Biochemical Technology, Faculty of Chemical Technology, Slovak Technical University, 812 37 Bratislava, Slovakia.
authors.forename: K
authors.initials: K
authors.lastname: Lesová
authors.forename: M
authors.initials: M
authors.lastname: Sturdíková
authors.forename: B
authors.initials: B
authors.lastname: Proksa
authors.forename: M
authors.initials: M
authors.lastname: Pigos
authors.forename: T
authors.initials: T
authors.lastname: Liptaj
mesh_terms: D001565:Benzoates / Q000378:metabolism; D003470:Culture Media; D004952:Esters / Q000378:metabolism; D005285:Fermentation; D005988:Glyceric Acids / Q000737:chemistry / Q000378:metabolism*; D010407:Penicillium / Q000254:growth & development / Q000378:metabolism*; D010940:Plant Proteins / Q000737:chemistry / Q000378:metabolism*; D014361:Trypsin Inhibitors; D000516:alpha-Amylases / Q000037:antagonists & inhibitors
chemical_list: D001565:Benzoates; D003470:Culture Media; D004952:Esters; D005988:Glyceric Acids; C436411:OR-1 metabolite; D010940:Plant Proteins; D014361:Trypsin Inhibitors; C433878:mitorubrinic acid; C042971:glyceric acid; D000516:alpha-Amylases