[Hypoglycemic treatment of type 2 diabetes].
BACKGROUND
Hyperglycaemia in type 2 diabetes results from reduced beta-cell function and insulin resistance. The treatment of type 2 diabetes must be targeted against both conditions to reduce symptoms of hyperglycaemia and the risk of diabetic late complications.


METHODS
In this review we cover the recent scientific documentation from long term studies on treatment effects. We also discuss the different treatments available.


RESULTS
Recent clinical trials have shown that lowering blood glucose levels over time significantly reduces development of microvascular complications in type 2 diabetes. There are several treatment options available which make adequate blood glucose control possible in patients with type 2 diabetes.


CONCLUSIONS
A reduction in the development of microvascular complications in type 2 diabetes is an achievable goal.
Thorsby
P
P
Diabeteslaboratoriet Hormonlaboratoriet Aker sykehus 0514 Oslo. per.thorsby@ioks.uio.no
Kilhovd
B
B
Sletmo
R
R
Martinsen
S
S
Birkeland
K I
KI
D001786:Blood Glucose / Q000378:metabolism; D002986:Clinical Trials as Topic; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000178:diet therapy / Q000188:drug therapy*; D003925:Diabetic Angiopathies / Q000517:prevention & control; D003927:Diet, Diabetic; D004359:Drug Therapy, Combination; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage; D007333:Insulin Resistance; D012016:Reference Values
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin