Bronchogenic carcinoma in lung transplant recipients.
Although lung transplant recipients have a higher prevalence of non-melanoma skin cancers and lymphoma than the general population, the same has not been noted for bronchogenic carcinoma. If an increased prevalence of bronchogenic carcinoma exists, contributing factors may include the high rate of previous tobacco use in this population and/or the chronic immunosuppression used to prevent allograft rejection. With time, the incidence of bronchogenic carcinoma in the lung transplant population is likely to parallel the increasing longevity and number of transplanted individuals. We describe 2 cases of bronchogenic carcinoma in lung transplant recipients that demonstrate the morbidity associated with the discovery or development of bronchogenic carcinoma in this population.
Stagner
L D
LD
Division of Pulmonary, Critical Care Medicine, Allergy and Immunology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Allenspach
L L
LL
Hogan
K K
KK
Willcock
L C
LC
Higgins
R S
RS
Chan
K M
KM
D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D002283:Carcinoma, Bronchogenic / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery; D016040:Lung Transplantation / Q000473:pathology*; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000473:pathology* / Q000601:surgery; D012086:Reoperation