title: [Clinical and experimental study on using Cassia angustifolia extract as enema after abdominal operation].
abstract: OBJECTIVE
  To investigate the curative effect and mechanism of using Cassia angustifolia extract (CAE) in treating gastrointestinal tract dysfunction after abdominal operations.
  
  
  METHODS
  Enema administration of CAE (Clyster method) was used.
  
  
  RESULTS
  The result of 130 patients was very effective in reducing the rate of gastrointestinal decompression, accelerating the restitution of borborygmi and the time of exhaustion. Animal experiment showed the CAE function is very obvious in enhancing the bowel movement of rats (P < 0.05). It can enhance peristalsis and contraction amplitude of vibration in the isolated ileum of rats (P < 0.05). It can push on the charcoal powder in intestinal tract of mice obviously (P < 0.05).
  
  
  CONCLUSIONS
  CAE could regulate disordered function of gastrointestinal tract after abdominal operations.
authors.affiliation: Qingdao Hospital of Integrated Traditional Chinese and Western Medicine, Shandong 266002.
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Yan
authors.forename: J
authors.initials: J
authors.lastname: Wang
mesh_terms: D000006:Abdomen, Acute / Q000601:surgery*; D000285:Administration, Rectal; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002366:Cassia / Q000627:therapeutic use*; D002648:Child; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D005767:Gastrointestinal Diseases / Q000601:surgery; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008875:Middle Aged; D008517:Phytotherapy; D018515:Plant Leaves / Q000627:therapeutic use; D010946:Plants, Medicinal; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004365:Drugs, Chinese Herbal