title: Dosimetry of beta-ray ophthalmic applicators: comparison of different measurement methods.
abstract: An international intercomparison of the dosimetry of three beta particle emitting ophthalmic applicators was performed, which involved measurements with radiochromic film, thermoluminescence dosimeters (TLDs), alanine pellets, plastic scintillators, extrapolation ionization chambers, a small fixed-volume ionization chambers, a diode detector and a diamond detector. The sources studied were planar applicators of 90Sr-90Y and 106Ru-106Rh, and a concave applicator of 106Ru-106Rh. Comparisons were made of absolute dosimetry determined at 1 mm from the source surface in water or water-equivalent plastic, and relative dosimetry along and perpendicular to the source axes. The results of the intercomparison indicate that the various methods yield consistent absolute dosimetry results at the level of 10%-14% (one standard deviation) depending on the source. For relative dosimetry along the source axis at depths of 5 mm or less, the agreement was 3%-9% (one standard deviation) depending on the source and the depth. Crucial to the proper interpretation of the measurement results is an accurate knowledge of the detector geometry, i.e., sensitive volume and amount of insensitive covering material. From the results of these measurements, functions which describe the relative dose rate along and perpendicular to the source axes are suggested.
authors.affiliation: National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA. csoares@nist.gov
authors.forename: C G
authors.initials: CG
authors.lastname: Soares
authors.forename: S
authors.initials: S
authors.lastname: Vynckier
authors.forename: H
authors.initials: H
authors.lastname: Järvinen
authors.forename: W G
authors.initials: WG
authors.lastname: Cross
authors.forename: P
authors.initials: P
authors.lastname: Sipilä
authors.forename: D
authors.initials: D
authors.lastname: Flühs
authors.forename: B
authors.initials: B
authors.lastname: Schaeken
authors.forename: F A
authors.initials: FA
authors.lastname: Mourtada
authors.forename: G A
authors.initials: GA
authors.lastname: Bass
authors.forename: T T
authors.initials: TT
authors.lastname: Williams
mesh_terms: D000409:Alanine / Q000737:chemistry; D001610:Beta Particles; D055592:Biophysical Phenomena; D001703:Biophysics; D001918:Brachytherapy / Q000379:methods*; D005128:Eye Diseases / Q000532:radiotherapy*; D015233:Models, Statistical; D019047:Phantoms, Imaging; D011868:Radioisotopes / Q000627:therapeutic use; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods*; D012238:Rhodium / Q000627:therapeutic use; D012428:Ruthenium / Q000627:therapeutic use; D013326:Strontium Radioisotopes / Q000627:therapeutic use; D014962:X-Ray Film; D015021:Yttrium Radioisotopes / Q000627:therapeutic use
chemical_list: D011868:Radioisotopes; D013326:Strontium Radioisotopes; D015021:Yttrium Radioisotopes; D012428:Ruthenium; D012238:Rhodium; D000409:Alanine