title: [Value of endonasal endoscopic surgery in the treatment of sphenoid cerebrospinal rhinorrheas. 15 cases].
abstract: Surgical management of cerebrospinal fluid leaks (CSFL) has improved these few past years with the development of paranasal sinus surgery under optical guidance. CSFL localized in the sphenoid sinus represent only 5 to 15% of all CSFL. The authors have analyzed a serie of 15 patients having undergone surgery from 1992 to 1999 for CSFL: 10 cases followed pituitary gland surgery realized through sublabial-transsphenoidal approach, 2 cases followed head trauma, 1 case followed a secondary neurosurgical procedure following recurrence of a rathke's cleft cyst, 1 case followed medical treatment of a bulky pituitary gland adenoma and 1 case was associated to an empty sella syndrome. The surgical procedure has relied on sphenoid sinus approach through the sphenoethmoidal recess (SER) (n = 8), transethmoidal approach (TE) (n = 2) or transseptal approach (TS) (n = 7) followed by a filling of the defect by a graft of fat with biological glue (n = 17). Sometimes it was associated to a cartilagenous graft (n = 7) when there was a bone defect. The average period of hospitalisation was 5.2 days (4-21), mean follow-up was 2.9 years (6 months-7 years).
  
  
  RESULTS
  The success rate was 80% (3 failures were observed), 2 patients underwent secondary procedures by TS approach with success. Our results combined with the literature data led us to propose an alternative surgical strategy adapted to each case. Endonasal surgery under optic guidance compared to the transrhinoseptal approach represents an attractive alternative with less undesirable iatrogenic consequences.
authors.affiliation: Hôpital Pasteur, Service d'ORL et de chirurgie de la Face et du Cou, 30 avenue de la voie romaine BP 69, 06002 Nice, France.
authors.forename: N
authors.initials: N
authors.lastname: Guevara
authors.forename: A
authors.initials: A
authors.lastname: Haddad
authors.forename: M
authors.initials: M
authors.lastname: Lonjon
authors.forename: P
authors.initials: P
authors.lastname: Paquis
authors.forename: J
authors.initials: J
authors.lastname: Santini
authors.forename: L
authors.initials: L
authors.lastname: Castillo
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation; D000328:Adult; D000465:Algorithms; D002356:Cartilage / Q000637:transplantation; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D003663:Decision Trees; D004724:Endoscopy / Q000379:methods* / Q000592:standards; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009666:Nose; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013101:Sphenoid Sinus; D014014:Tissue Adhesives / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014014:Tissue Adhesives