title: Arrhythmias in neurofibromatosis. A case report and review of the literature.
abstract: Patients with neurofibromatosis have a higher incidence of anatomic cardiac abnormalities. However, there is little data regarding incidence of arrhythmias in this population. It is known that these patients have a higher mortality than the normal population, and it is possible that some deaths may be due to preventable causes such as cardiac arrhythmias. We report a patient with neurofibromatosis who was treated for a refractory seizure disorder for 8 years. However, video/EEG monitoring demonstrated that the patient had recurrent syncopal seizures secondary to sinus node dysfunction. Complete resolution of symptoms occurred after a permanent pacemaker implantation. We believe this is the first reported case of sinus node dysfunction associated with neurofibromatosis.
authors.affiliation: Section of Cardiology, Medical College of Georgia, Augusta, GA 30912-3105, USA.
authors.forename: S
authors.initials: S
authors.lastname: Verma
authors.forename: S
authors.initials: S
authors.lastname: Ahmed
authors.forename: S B
authors.initials: SB
authors.lastname: Gudapati
authors.forename: D W
authors.initials: DW
authors.lastname: King
authors.forename: K J
authors.initials: KJ
authors.lastname: Meador
authors.forename: R
authors.initials: R
authors.lastname: Ahmed
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004562:Electrocardiography; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000209:etiology*; D005260:Female; D006801:Humans; D017253:Neurofibromatoses / Q000175:diagnosis*; D010138:Pacemaker, Artificial; D012804:Sick Sinus Syndrome / Q000175:diagnosis* / Q000628:therapy; D013575:Syncope / Q000209:etiology*; D014741:Video Recording