title: Evolution of a synthetic approach to CP-263,114.
abstract: [structure: see text] Three different approaches to the carbocyclic core of CP-263,114 are presented that illustrate a strategic evolution from an oxy-Cope rearrangement to variants of the Wharton fragmentation.
authors.affiliation: Sterling Chemistry Laboratory, Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Njardarson
authors.forename: J L
authors.initials: JL
authors.lastname: Wood
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004791:Enzyme Inhibitors / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D008299:Maleic Anhydrides / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: C104957:CP 263114; D004791:Enzyme Inhibitors; D007202:Indicators and Reagents; D008299:Maleic Anhydrides