Case report. Successful outcome of invasive nasal sinus zygomycosis in a child with relapsed acute lymphoblastic leukaemia due to liposomal amphotericin B.
We report a case of life-threatening nasal sinus zygomycosis that developed during remission induction therapy for a relapsed acute lymphoblastic leukaemia. The patient was successfully treated with liposomal amphotericin B and granulocyte-colony stimulating factor followed by surgical reconstruction of the resultant cutaneous defect.
Wali
Y A
YA
al Lamki
Z
Z
al Kindi
H
H
Taqi
A M
AM
Shah
W
W
Soliman
H
H
Zackaria
M
M
al Okbi
H
H
D020095:Absidia; D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D002648:Child; D003881:Dermatomycoses / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000150:complications / Q000188:drug therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D012852:Sinusitis / Q000150:complications / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B