title: A renal hemangiosarcoma causing hematuria in a dog.
abstract: A 14.5-year-old male dog was presented with stranguria and hematuria of 1-month duration. Hematology and blood chemistry revealed a neutrophilia, mild azotemia and a mild decrease in the packed cell volume. Urinalysis showed high specific gravity (> 1.040 g/mL), hematuria, proteinuria and mild bilirubinuria. On physical examination, a firm oval mass located caudal to the distended urinary bladder, was palpated. Differential diagnoses included prostatitis, prostatic neoplasm, prostatic hyperplasia, and abscess. The enlarged prostate was suspected to be the cause of hematuria, and a total prostatectomy was performed. Histologically, the prostate was affected by a prostatitis with cystic papillary hyperplasia of the epithelium. The dog's condition continued to deteriorate, and death occurred 1 week later. Necropsy showed a tumor mass, approximately 5 x 4 x 3 cm in size, between the abdominal aorta and the left kidney, where the adrenal glands were embedded. Lesions were found in the kidneys, adrenal gland, lungs, heart, liver, intestine, and serosa of viscera, while the spleen was spared. This hemangiosarcoma most likely arose from the renal arteries, resulting in diffuse lesions in the kidneys thought to be the cause of hematuria.
authors.affiliation: Department of Veterinary Medicine, National Taiwan University, Taipei, ROC.
authors.forename: F I
authors.initials: FI
authors.lastname: Wang
authors.forename: H L
authors.initials: HL
authors.lastname: Su
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D004184:Dirofilariasis / Q000150:complications; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D006394:Hemangiosarcoma / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D006417:Hematuria / Q000209:etiology / Q000662:veterinary*; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male; D009362:Neoplasm Metastasis; D011468:Prostatectomy; D011470:Prostatic Hyperplasia / Q000175:diagnosis; D011507:Proteinuria / Q000209:etiology; D012077:Renal Artery / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor