title: Simultaneous measurement of binding constants and unwinding angles by gel electrophoresis.
authors.affiliation: Department of Chemistry, Yale University, New Haven, Connecticut 06520, USA.
authors.forename: S M
authors.initials: SM
authors.lastname: Zeman
authors.forename: D M
authors.initials: DM
authors.lastname: Crothers
mesh_terms: D000818:Animals; D001665:Binding Sites; D004247:DNA / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D004264:DNA Topoisomerases, Type I; D003630:Daunorubicin; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods*; D004996:Ethidium; D006801:Humans; D066298:In Vitro Techniques; D007364:Intercalating Agents; D007700:Kinetics; D008024:Ligands; D009690:Nucleic Acid Conformation
chemical_list: D007364:Intercalating Agents; D008024:Ligands; D004247:DNA; D004264:DNA Topoisomerases, Type I; D004996:Ethidium; D003630:Daunorubicin