title: A pair of 24-hydroperoxyl epimeric dammarane saponins from flower-buds of Panax ginseng.
abstract: Further investigation on the saponins of the flower-buds of Panax ginseng C. A. Meyer has resulted in the isolation and structural elucidation of a pair of new 24-epimers of dammarane type saponins named ginsenoside I and II. The structures of the epimers were characterized on the basis of chemical and spectral evidence as 3-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl]-20-S-O-beta-D-glucopyranosyl-3beta, 12beta,20(S)-trihydroxy-24xi-hydroperoxydammar-25-ene, except for their C-24 configurations. Ginsenoside I is a new triterpene glycoside, and ginsenoside II is a known compound first isolated from a natural plant.
authors.affiliation: Department of Natural Medicinal Chemistry, Shenyang Pharmaceutical University, China. fengqiu2000@netease.com
authors.forename: F
authors.initials: F
authors.lastname: Qiu
authors.forename: Z Z
authors.initials: ZZ
authors.lastname: Ma
authors.forename: S X
authors.initials: SX
authors.lastname: Xu
authors.forename: X S
authors.initials: XS
authors.lastname: Yao
authors.forename: C T
authors.initials: CT
authors.lastname: Che
authors.forename: Y J
authors.initials: YJ
authors.lastname: Chen
mesh_terms: D002851:Chromatography, High Pressure Liquid; D036145:Ginsenosides; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D005894:Panax / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D000097669:Dammaranes
chemical_list: D036145:Ginsenosides; D012503:Saponins; D014315:Triterpenes; D000097669:Dammaranes; C441661:ginsenoside I