[Cortinarius poisoning. Analysis of cases in the literature].
Cortinarius spp. poisoning is characterized by a delayed acute renal failure (ARF). The main features of this severe poisoning are still poorly known and often overlooked. The aim of this review of the literature was a better description of Cortinarius spp. poisoning.


METHODS
The main medical databases were searched and analysed.


RESULTS
245 cases were collected and 90 cases could be analysed in details. Gastrointestinal disorders appeared a few days after the ingestion of the mushrooms (median: three days). The renal phase is delayed (median: 8.5 days). Hepatic failure and muscular lesions are highly questionable. Treatment is supportive in half of the cases, ARF progressed towards chronic renal failure, which progressed in 70% of the cases towards terminal renal failure.


CONCLUSIONS
Cortinarius spp. poisoning is severe. Ingestion of Cortinarius species must be systematically suspected whenever tubulo-interstitial nephritis is diagnosed.
Saviuc
P
P
Unité de toxicologie clinique, Département pluridisciplinaire de médecine, Centre hospitalier universitaire de Grenoble. Psaviuc@chu-grenoble.fr
Garon
D
D
Danel
V
V
Richard
J M
JM
D058186:Acute Kidney Injury / Q000139:chemically induced; D000328:Adult; D000363:Agaricales; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006801:Humans; D007676:Kidney Failure, Chronic / Q000139:chemically induced; D017093:Liver Failure / Q000139:chemically induced; D008297:Male; D009145:Mushroom Poisoning / Q000453:epidemiology / Q000628:therapy; D011379:Prognosis