title: [Clinical laboratory diagnosis and aging. 3: Evaluation of a study of aging--complete blood and urine status].
abstract: The results of the determination of hematologic values from 262 men and 242 women, participants of an aging study and half of each group 44.4 +/- 0.9 and 63.0 +/- 0.9 (men) and 44.4 +/- 0.9 and 62.8 +/- 0.8 years old (women), respectively, are compared. In men, one analyte (hemoglobin decreasing) and four indices show significant differences (MCV increasing, MCH decreasing, MCHC decreasing, RDW increasing). In the older group, the iron level and the transferrin saturation are also significantly lower. In women, erythrocytes and the hematocrit are significantly higher in the older group whereas the indices MCH and MCHC are lower and the RDW increases. At the same time, the iron level, transferrin and the transferrin saturation decrease whereas ferritin doubles. The sex differences of the hematologic parameters are more pronounced in the younger participants and especially remarkable in ferritin in both age groups. The results of the semiquantitative analysis of ten urine parameters by reagent strip show differences with respect to sex (e.g., leucocytes and erythrocytes) and age (e.g., specific gravity, pH, nitrite, protein, erythrocytes). The usefulness of the estimation of glucose in urine is discussed in connection with the corresponding serum glucose levels.
authors.affiliation: Universität Leipzig Institut für Klinische Chemie und Pathobiochemie Liebigstr. 27 04103 Leipzig, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Martin
authors.forename: K
authors.initials: K
authors.lastname: Langenhan
authors.forename: M
authors.initials: M
authors.lastname: Huth
authors.forename: I
authors.initials: I
authors.lastname: Sauer
authors.forename: C
authors.initials: C
authors.lastname: Weisbrich
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001774:Blood Chemical Analysis; D003955:Diagnostic Tests, Routine; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012016:Reference Values; D014556:Urine / Q000737:chemistry*