The efficacy of continuous infusion flucloxacillin in home therapy for serious staphylococcal infections and cellulitis.
The efficacy and safety of continuous infusion flucloxacillin as home-based treatment was assessed in 62 consecutive patients with proven serious methicillin-susceptible Staphylococcus aureus (MSSA) infections (n = 36) and cellulitis (n = 26). The treatment was well tolerated and resulted in cure or adequate suppression of infection in 27 of 28 (96%) patients in the serious MSSA infection group, and in 24 of 26 (92%) patients in the cellulitis group.
Howden
B P
BP
Department of Infectious Diseases, Austin and Repatriation Medical Centre, Studley Road, Heidelberg, Victoria 3084, Australia. Ben.Howden@med.monash.edu.au
Richards
M J
MJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002481:Cellulitis / Q000188:drug therapy*; D005260:Female; D005436:Floxacillin / Q000008:administration & dosage*; D018718:Home Infusion Therapy / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D007260:Infusion Pumps / Q000009:adverse effects / Q000706:statistics & numerical data; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010406:Penicillins / Q000008:administration & dosage*; D013203:Staphylococcal Infections / Q000188:drug therapy*; D016896:Treatment Outcome
D010406:Penicillins; D005436:Floxacillin