title: Can you still see the cochlea for the molecules?
abstract: It is now established that the mammalian cochlea uses active amplification of incoming sound to achieve sensitivity. Cellular details are emerging slowly. Recent studies of sensory hair cells have highlighted the possible molecular bases for amplification and the components of sensitivity regulation within the cochlea: a synthesis is likely to depend on effective and physiologically informed modelling.
authors.affiliation: Department of Physiology, University College London, Gower Street, WC1E 6BT, London, UK. j.ashmore@ucl.ac.edu
authors.forename: J F
authors.initials: JF
authors.lastname: Ashmore
authors.forename: F
authors.initials: F
authors.lastname: Mammano
mesh_terms: D000818:Animals; D027321:Anion Transport Proteins; D001696:Biomechanical Phenomena; D003051:Cochlea / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D004594:Electrophysiology; D006198:Hair Cells, Auditory / Q000502:physiology; D006801:Humans; D007473:Ion Channels / Q000502:physiology; D008954:Models, Biological; D011506:Proteins / Q000502:physiology; D000076988:Sulfate Transporters
chemical_list: D027321:Anion Transport Proteins; D007473:Ion Channels; D011506:Proteins; C498719:SLC26A5 protein, human; D000076988:Sulfate Transporters