[Clinical and experimental study on the Houpu Mahuang oral liquid in treating bronchial asthma].
OBJECTIVE
To probe into the curative effect and mechanism of action of the Houpu Mahuang oral liquid (HPMH) in treating bronchial asthma.


METHODS
The pulmonary function and level of serum IgE of the patients were determined before and after HPMH treatment. The anti-allergic reaction and relieving spasm effect of HPMH in animal were also observed.


RESULTS
HPMH is not only effective in improving clinical symptoms and pulmonary function (P < 0.05), so as to lower the abnormal raising of IgE (P < 0.01), but also has a notable inhibitory effect for passive allergic reaction of rat's skin, it can relieve spasm.


CONCLUSIONS
HPMH is effective in relieving spasm, antiallergic reaction, it can improve the symptoms of bronchial asthma.
Yuan
X
X
Henan Academy of TCM, Zhengzhou 450004.
Ning
X
X
Liu
F
F
D000328:Adult; D000818:Animals; D018926:Anti-Allergic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D001980:Bronchi / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009126:Muscle Relaxation / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010323:Passive Cutaneous Anaphylaxis / Q000187:drug effects; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D018926:Anti-Allergic Agents; D004365:Drugs, Chinese Herbal; D007073:Immunoglobulin E