title: Multiple osteochondroses of bilateral knee joints.
abstract: We experienced a patient with a combination of multiple osteochondroses: Blount's disease, bipartite patella, and Sinding-Larsen-Johansson disease in the left knee, and a combination of bipartite patella and Osgood-Schlatter disease in the right knee. The patient was a healthy, active 12-year-old boy with bilateral knee pain. He had been diagnosed with Blount's disease of the left tibia at 2 years of age, and had been treated with open wedge osteotomy. He was diagnosed with bilateral bipartite patellae at the age of 9 years, and was diagnosed with Osgood-Schlatter disease in the right knee and Sinding-Larsen-Johansson disease in the left knee at 10 years of age. The second growth spurt was observed during this period. At 11 years of age, he was diagnosed with an osteochondral fracture of the left lateral femoral condyle and was observed without surgery. This patient showed the sequential appearance of an ossification disorder, probably due to the abnormal response of enchondral ossification to mechanical stress. Overuse in this growth period may have played a role in the development of these osteochondroses. The osteochondral fracture was probably caused by a disruption at one of the weakest parts of the developing skeleton, between the ossification center and the overlying cartilage in the background of an ossification disorder.
authors.affiliation: Department of Orthopedic Surgery, Niigata University School of Medicine, 1-751 Asahimachi, Niigata 951-8510, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Segawa
authors.forename: G
authors.initials: G
authors.lastname: Omori
authors.forename: Y
authors.initials: Y
authors.lastname: Koga
mesh_terms: D001827:Body Height; D002648:Child; D006801:Humans; D007719:Knee Joint; D008297:Male; D010007:Osteochondritis / Q000175:diagnosis* / Q000628:therapy