title: Coronary artery stenoses: a phantom study using contrast enhanced three-dimensional electron beam tomography.
abstract: This paper evaluated the accuracy of electron beam tomographic angiography (EBA) with conventional coronary arteriography (CCA) using four graded artificial stenoses in a postmortem swine coronary phantom model. The sensitivity, specificity, and accuracy of EBA for diagnosing significant stenosis (> or =50% stenosis) were 94.3%, 96.7%, and 95.8%, respectively. The diagnostic accuracy of EBA had no significant difference with CCA (chi(2)=0.0162; P>.05). EBA three-dimensional (3D) procedures had high interobserver reproducibility (k=.92-.95, P>.05). Maximum intensity projection (MIP) was the most sensitive and curved planar reformation (CPR) was the most accurate 3D procedure for quantitatively identifying coronary stenosis. EBA yields promising results concerning the visualization of coronary artery stenosis with high accuracy for stenoses >50%.
authors.affiliation: Department of Radiology, FuWai Cardiovascular Institute and Hospital, Peking Union Medical College, Beijing 100037, China.
authors.forename: B
authors.initials: B
authors.lastname: Lu
authors.forename: R P
authors.initials: RP
authors.lastname: Dai
authors.forename: H
authors.initials: H
authors.lastname: Bai
authors.forename: S
authors.initials: S
authors.lastname: He
authors.forename: B L
authors.initials: BL
authors.lastname: Jing
authors.forename: S L
authors.initials: SL
authors.lastname: Jiang
authors.forename: N
authors.initials: N
authors.lastname: Zhuang
authors.forename: X G
authors.initials: XG
authors.lastname: Sun
authors.forename: M J
authors.initials: MJ
authors.lastname: Budoff
mesh_terms: D000818:Animals; D003287:Contrast Media; D017023:Coronary Angiography / Q000379:methods; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004195:Disease Models, Animal; D021621:Imaging, Three-Dimensional; D019047:Phantoms, Imaging; D011856:Radiographic Image Enhancement / Q000379:methods*; D012680:Sensitivity and Specificity; D013552:Swine; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media