title: MR renography by semiautomated image analysis: performance in renal transplant recipients.
abstract: We evaluated a method of semiautomated analysis of dynamic MR image series in renal transplants. Nine patients were studied twice, with an average time interval of 7 days. MR examination consisted of a run of 256 T1-weighted coronal scans (GE; TR/TE/flip: = 11/3.4/60 degrees; slice thickness = 6 mm; temporal resolution = 2 seconds). Gadolinium-DTPA (0.05 mmol/kg) was injected with an injector pump (5 ml/seconds). MR renographs of the cortex and medulla were obtained by segmentation of the renal transplant and placement of two regions of interest (ROIs) overlying the peripheral and central renal parenchyma. In the first 100 frames of the renographs, analysis of variance (ANOVA) demonstrated significant intraclass correlation coefficients with mean values for the cortex and medulla of 0.47 and 0.59, respectively. We conclude that the procedure is a robust technique that generates meaningful signal curves.
authors.affiliation: Department of Radiology, University Hospital Maastricht, Maastricht, The Netherlands. depriester@planet.nl
authors.forename: J A
authors.initials: JA
authors.lastname: de Priester
authors.forename: A G
authors.initials: AG
authors.lastname: Kessels
authors.forename: E L
authors.initials: EL
authors.lastname: Giele
authors.forename: J A
authors.initials: JA
authors.lastname: den Boer
authors.forename: M H
authors.initials: MH
authors.lastname: Christiaans
authors.forename: A
authors.initials: A
authors.lastname: Hasman
authors.forename: J M
authors.initials: JM
authors.lastname: van Engelshoven
mesh_terms: D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007668:Kidney / Q000473:pathology; D016030:Kidney Transplantation / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA