Prothrombotic genetic markers.
The last decade has been characterized by an explosion of research studies on genetic epidemiology. In particular, as far as ischemic heart disease is concerned, a lot of research was focused on prothrombotic genetic risk factors. Unfortunately, the success of this approach in the field of venous thrombosis has not been replicated in the field of myocardial infarction. In the present editorial, a comment on the studies already available is provided and the possible limitations of the present approach are analyzed.
Rossi
M L
ML
A. De Gasperis Cardiology Department, Hospital Niguarda Ca' Granda, Milan, Italy. marcolrossi@hotmail.com
Merlini
P A
PA
Ardissino
D
D
D003328:Coronary Thrombosis / Q000235:genetics*; D005167:Factor VII / Q000235:genetics; D005340:Fibrinogen / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D009154:Mutation; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000235:genetics; D011516:Prothrombin / Q000235:genetics*; D012307:Risk Factors
D005819:Genetic Markers; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D005167:Factor VII; D011516:Prothrombin; D005340:Fibrinogen