title: [The analysis of the relationship between integrated grade of the gray and other karyometric parameters in the precancerous lesions and laryngeal cancer].
abstract: The authors assessed morphometrically the parameters describing nuclei of the normal epithelium (superficial and basal layers), precancerous lesions (dysplasia and keratosis) and laryngeal cancer in the postoperative samples of 12 patients treated in the II Laryngology Clinic Silesian Medical Academy in Zabrze. Then the relationship between the integrated grade of grey (the index of changes in DNA structure) and the others kariometric parameters was evaluated. The value of the integrated grade of grey was the smallest in the superficial layers nuclei and the biggest in the laryngeal cancer one. The evaluation of the relationship was made by using the Spearman Rang Test. The integrated grade of grey was correlated with others quantitative nuclear measurements, though the correlation power was differ in the individual morphometrical stages.
authors.affiliation: Katedra i Oddział Kliniczny Laryngologii Slaskiej AM w Zabrzu.
authors.forename: G
authors.initials: G
authors.lastname: Namysłowski
authors.forename: W
authors.initials: W
authors.lastname: Scierski
authors.forename: J
authors.initials: J
authors.lastname: Nozyński
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007620:Karyometry / Q000379:methods; D007642:Keratosis / Q000235:genetics / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000235:genetics* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011230:Precancerous Conditions / Q000235:genetics* / Q000473:pathology*