[Isoflavones from Glycyrrhiza eurycarpa].
A new isoflavone, named eurycarpin A and a new natural product isoflavone named eurycarpin B have been isolated from the roots of Glycyrrhiza eurycarpa P. C. Li. Their structures were determined to be 7,2',4'-trihydroxy-3'-(3,3-dimethylallyl) isoflavone(I) and 7,2'-dihydroxy-6",6"-dimethylpyrano-(2",3":4',3') isoflavone(II) on the basis of spectroscopic analysis (UV, EI-MS, 1HNMR, 13CNMR, NOE difference and HMBC). In addition, three known isoflavones, licoisoflavone A, calycosin and formononetin, were obtained for the first time from this plant.
Zhang
Y M
YM
Institute of Medicinal Plant, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100094.
Xu
X D
XD
Hu
B H
BH
Liu
Q
Q
Hou
C Y
CY
Liu
Y L
YL
Yang
J S
JS
D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D006035:Glycyrrhiza / Q000737:chemistry*; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010946:Plants, Medicinal
D004365:Drugs, Chinese Herbal; D007529:Isoflavones; C437402:eurycarpin A; C121707:7,3'-dihydroxy-4'-methoxyisoflavone; C007768:formononetin; C437403:eurycarpin B