title: Regional hyperthermia applicator design using FDTD modelling.
abstract: Recently published results confirm the positive effect of regional hyperthermia combined with external radiotherapy on pelvic tumours. Several studies have been published on the improvement of RF annular array applicator systems with dipoles and a closed water bolus. This study investigates the performance of a next-generation applicator system for regional hyperthermia with a multi-ring annular array of antennas and an open water bolus. A cavity slot antenna is introduced to enhance the directivity and reduce mutual coupling between the antennas. Several design parameters, i.e. dimensions, number of antennas and operating frequency, have been evaluated using several patient models. Performance indices have been defined to evaluate the effect of parameter variation on the specific absorption rate (SAR) distribution. The performance of the new applicator type is compared with the Coaxial TEM. Operating frequency appears to be the main parameter with a positive influence on the performance. A SAR increase in tumour of 1.7 relative to the Coaxial TEM system can be obtained with a three-ring, six-antenna per ring cavity slot applicator operating at 150 MHz.
authors.affiliation: Department of Radiation Oncology, University Medical Centre Utrecht, O Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Kroeze
authors.forename: J B
authors.initials: JB
authors.lastname: Van de Kamer
authors.forename: A A
authors.initials: AA
authors.lastname: De Leeuw
authors.forename: J J
authors.initials: JJ
authors.lastname: Lagendijk
mesh_terms: D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation* / Q000379:methods*; D008297:Male; D015233:Models, Statistical; D010386:Pelvic Neoplasms / Q000532:radiotherapy* / Q000628:therapy*; D019047:Phantoms, Imaging; D011471:Prostatic Neoplasms / Q000532:radiotherapy / Q000628:therapy; D011878:Radiotherapy / Q000295:instrumentation* / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy / Q000628:therapy; D014867:Water
chemical_list: D014867:Water