[Ultramicrostructure study of artificial bone composite with high biological induction in repairing bone defect].
The scanning electric microscopy (SEM). X-ray energy graph and Ca, P contents analysis were adopted in studying the mechanism and superiority of two different composite artificial bones (HA-bBMP-Co and HA-Co) to repair segmental bone defect in rabbits. The results indicated that HA-bBMP-Co had a double effects of bone induction and bone conduction. No difference of P content in two weeks after reconstructive surgery was found, but in other periods, there was an obvious difference in Ca and P content between HA-bBMP-Co group and HA-Co group (P < 0.05).
Fei
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W
Department of Oral and Maxillofacial Surgery, West China University of Medical Sciences.
Wang
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D
Liu
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D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use; D018786:Bone Substitutes / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use; D017886:Durapatite / Q000627:therapeutic use; D005260:Female; D008297:Male; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D010012:Osteogenesis; D011817:Rabbits; D011897:Random Allocation; D014457:Ulna / Q000648:ultrastructure*; D014458:Ulna Fractures / Q000601:surgery*
D019485:Bone Morphogenetic Proteins; D018786:Bone Substitutes; D003094:Collagen; D017886:Durapatite