title: Maintenance of tooth color after prophylaxis: comparison of three dentifrices.
abstract: Pellicle rapidly accumulates on tooth surfaces after prophylaxis and may acquire cosmetically unacceptable levels of stain. A three-month clinical trial was conducted to evaluate stain prevention by a new silica-based tartar control whitening dentifrice (Crest Extra Whitening) compared to marketed tartar control baking soda peroxide whitening and regular dentifrice controls. Prior to the trial, a one-month screening exercise was conducted to identify adult subjects who accumulated extrinsic tooth stain after dental prophylaxis. A total of 672 subjects were stratified based on tooth whiteness, gender and tobacco usage, then given a dental prophylaxis and randomized into one of three dentifrice treatment groups. All product use was unsupervised. Change in tooth whiteness (delta L*) was determined by comparing colorimeter measurements collected on the facial surfaces of the four central incisors at months 1 and 3 to baseline. Ninety-six percent of subjects completed the three-month study. At both one and three months, the two whitening dentifrices did not differ from baseline in terms of delta L*. In contrast, the regular control had delta L* values of -0.26 and -0.39 at one and three months, respectively, differing significantly from baseline at both time points. Each of the whitening dentifrices differed statistically from the regular control in stain accumulation (p < or = 0.001) at one and three months, but were not different from each other. In general, all three test dentifrices were well tolerated. These data demonstrate the effectiveness of the new tartar control whitening dentifrice in preventing stain accumulation after dental prophylaxis compared to the marketed regular dentifrice control.
authors.affiliation: School of Dentistry, Indiana University, Indianapolis, IN, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Isaacs
authors.forename: R D
authors.initials: RD
authors.lastname: Bartizek
authors.forename: T S
authors.initials: TS
authors.lastname: Owens
authors.forename: P A
authors.initials: PA
authors.lastname: Walters
authors.forename: R W
authors.initials: RW
authors.lastname: Gerlach
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002327:Cariostatic Agents / Q000737:chemistry / Q000627:therapeutic use; D003116:Color; D003124:Colorimetry; D003728:Dental Calculus / Q000517:prevention & control; D044622:Dental Pellicle; D003777:Dental Prophylaxis; D003802:Dentifrices / Q000737:chemistry / Q000627:therapeutic use*; D011756:Diphosphates / Q000737:chemistry / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016877:Oxidants / Q000737:chemistry / Q000627:therapeutic use; D010545:Peroxides / Q000737:chemistry / Q000627:therapeutic use; D012449:Safety; D012822:Silicon Dioxide / Q000737:chemistry / Q000627:therapeutic use; D012907:Smoking; D017693:Sodium Bicarbonate / Q000737:chemistry / Q000627:therapeutic use; D012969:Sodium Fluoride / Q000737:chemistry / Q000627:therapeutic use; D014070:Tooth / Q000473:pathology*; D014073:Tooth Bleaching; D014075:Tooth Discoloration / Q000517:prevention & control*
chemical_list: D002327:Cariostatic Agents; D003802:Dentifrices; D011756:Diphosphates; D016877:Oxidants; D010545:Peroxides; D012822:Silicon Dioxide; C403632:calcium peroxide; D017693:Sodium Bicarbonate; D012969:Sodium Fluoride