title: Studies on the reactivity of a tertiary allylic alcohol in an acetophenonic series, a model for natural products synthesis.
abstract: The synthesis of benzopyranic simplified analogues of dibenzopyranic natural compounds is described, together with the access to a precursor of a new furobenzopyranic natural product. These natural products have anti-cancer activity. The 1,3-diacetoxy-2-acetyl-4-(3-hydroxy-3-methylbut-1-enyl)benzene synthone is used as a common precursor to these structures.
authors.affiliation: SONAS, UFR des Sciences Pharmaceutiques et Ingénierie de la Santé, Angers, France.
authors.forename: J J
authors.initials: JJ
authors.lastname: Hélesbeux
authors.forename: D
authors.initials: D
authors.lastname: Séraphin
authors.forename: O
authors.initials: O
authors.lastname: Duval
authors.forename: P
authors.initials: P
authors.lastname: Richomme
authors.forename: J
authors.initials: J
authors.lastname: Bruneton
mesh_terms: D000098:Acetophenones / Q000138:chemical synthesis*; D000438:Alcohols / Q000737:chemistry*; D000498:Allyl Compounds / Q000138:chemical synthesis*; D001578:Benzopyrans / Q000138:chemical synthesis*; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D029759:Calophyllum / Q000737:chemistry
chemical_list: D000098:Acetophenones; D000438:Alcohols; D000498:Allyl Compounds; D001578:Benzopyrans; D001688:Biological Products; C038699:acetophenone