Acute flaccid paralysis syndrome associated with echovirus 19, managed with pleconaril and intravenous immunoglobulin.
We describe a 39-year-old woman who had undergone bilateral lung and renal transplantation and who was admitted to the hospital with acute onset of flaccid paralysis of the left leg due to echovirus 19 infection. The patient was treated with pleconaril and intravenous immunoglobulin, which correlated with clinical and laboratory evidence of improvement.
Starlin
R
R
Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA.
Reed
N
N
Leeman
B
B
Black
J
J
Trulock
E
E
Mundy
L M
LM
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D004457:Echovirus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000009:adverse effects; D016040:Lung Transplantation / Q000009:adverse effects; D010069:Oxadiazoles / Q000627:therapeutic use*; D010080:Oxazoles; D010264:Paraplegia / Q000188:drug therapy* / Q000382:microbiology*
D000998:Antiviral Agents; D016756:Immunoglobulins, Intravenous; D010069:Oxadiazoles; D010080:Oxazoles; C115201:pleconaril