[The influence of perftoran on the course of acute pulmonary injury syndrome in patients with destructive pancreatitis].
The respiration disorders are revealed in patients with an acute destructive pancreatitis in early and late terms of the disease. Occurrence of an acute pulmonary injury syndrome (APIS) worsens the disease prognosis, enhances mortality. In complex of intensive therapy the perftoran (Russia) infusion in 5 ml/kg of body mass dose are applied in 10 patients with destructive pancreatitis. Main indexes of the blood gases composition and of hemodynamics were controlled. It was established that application of perftoran detains the APIS occurrence in the patients with severe pancreatitis, averts the polyorgan insufficiency occurrence, promotes the various kinds of hypoxia correction, stimulates cardiac activity, raises the blood oxygen capacity, improves microcirculation. Application of perftoran was substantiated in complex of treatment of patients with an acute destructive pancreatitis for prophylaxis of occurrence and for elimination of APIS.
Shevchuk
I
I
Titov
I
I
D000328:Adult; D000368:Aged; D018450:Disease Progression; D005260:Female; D005466:Fluorocarbons / Q000627:therapeutic use*; D006439:Hemodynamics; D006801:Humans; D008168:Lung / Q000098:blood supply; D008171:Lung Diseases / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications*
D005466:Fluorocarbons; C063334:perftoran