Evaluation of efficacy and safety of iron polymaltose complex and folic acid (Mumfer) vs iron formulation (ferrous fumarate) in female patients with anaemia.
Treatment of iron deficiency anaemia with conventional oral preparations is handicapped by unpredictable haematological response in addition to potential for irritating gastrointestinal adverse events. Iron polymaltose complex (IPC), a novel oral iron formulation with better absorbability, predictable haematinic response and less side effects was compared with oral ferrous fumarate in 100 female patients with documented iron deficiency anaemia. Clinical parameters (pallor, weakness) as well as biochemical parameters (Hb, serum iron, total iron binding capacity) show favourable changes with IPC; the physician and patient assessment also favour IPC over ferrous fumarate.
Reddy
P S
PS
Department of PSM, LTMM College & LTMG Hospital, Sion, Mumbai.
Adsul
B B
BB
Gandewar
K
K
Korde
K M
KM
Desai
A
A
D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000188:drug therapy*; D003906:Developing Countries; D004338:Drug Combinations; D005260:Female; D005290:Ferric Compounds / Q000008:administration & dosage* / Q000009:adverse effects; D005296:Ferrous Compounds / Q000008:administration & dosage* / Q000009:adverse effects; D005492:Folic Acid / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D011446:Prospective Studies; D016896:Treatment Outcome
D004338:Drug Combinations; D005290:Ferric Compounds; D005296:Ferrous Compounds; D005492:Folic Acid; C031621:ferrous fumarate; C013276:teferrol