title: Sex and salt hormones: rapid effects in epithelia.
abstract: Recent evidence points to protein kinase C isoforms as highly specific receptors for aldosterone and estradiol in epithelia. The end targets of the kinase activation are Na(+)/H(+) exchange and K(+) and Ca(2+) channels. The physiological role of the nongenomic response is to increase electrolyte absorption and inhibit secretion in pluripotential epithelia.
authors.affiliation: Wellcome Trust Cellular Physiology Research Unit, Department of Physiology, University College Cork, Ireland.
authors.forename: B J
authors.initials: BJ
authors.lastname: Harvey
authors.forename: S
authors.initials: S
authors.lastname: Condliffe
authors.forename: C M
authors.initials: CM
authors.lastname: Doolan
mesh_terms: D000450:Aldosterone / Q000502:physiology*; D000818:Animals; D004848:Epithelium / Q000502:physiology; D004958:Estradiol / Q000502:physiology*; D006801:Humans; D012727:Sex Characteristics; D015398:Signal Transduction / Q000502:physiology
chemical_list: D000450:Aldosterone; D004958:Estradiol