title: Investigation of vertebral "end plate sclerosis".
abstract: OBJECTIVE
  To evaluate the association between vertebral "end plate sclerosis" and neck pain.
  
  
  METHODS
  A retrospective study was carried out of lateral cervical spine radiographs with a Picture Archive and Communication System (PACS).
  
  
  METHODS
  Two hundred patients' files were randomly assessed, comprising four equal groups, A to D. The mean ages of the patients were 62+/-7.4 years, 61+/-7.5 years, 40+/-5.6 years and 23+/-5.6 years respectively. In group A, all patients had symptoms of neck pain and a radiographic diagnosis of "end plate sclerosis" of the cervical spine. In groups B to D, asymptomatic patients were recruited and their age groups were 50-69, 30-49 and 10-29 years respectively. Using the PACS, the radiographic density and the sagittal diameter, thickness and area of the end plates at the C5 level were measured.
  
  
  CONCLUSIONS
  No significant differences were found in the radiographic density of the end plates either between the symptomatic and asymptomatic groups (groups A and B), or between different age groups (groups B, C and D). A significant increase in end plate area and thickness was found, however, in both group B (P<0.005) and group C (P<0.01) in comparison with group D. This indicates that the extent of end plate sclerosis increases with age. Our results suggest that the radiographic density of cervical vertebral end plates correlates neither with neck pain nor with increasing age. The radiological sign of "end plate sclerosis" may be over-reported, further limiting its value in the assessment of patients with cervical spondylosis.
authors.affiliation: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.
authors.forename: S W
authors.initials: SW
authors.lastname: Lee
authors.forename: A G
authors.initials: AG
authors.lastname: Mathie
authors.forename: J E
authors.initials: JE
authors.lastname: Jackson
authors.forename: S P
authors.initials: SP
authors.lastname: Hughes
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging; D002648:Child; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D019547:Neck Pain / Q000000981:diagnostic imaging / Q000209:etiology; D011859:Radiography; D011873:Radiology Information Systems; D012189:Retrospective Studies; D012598:Sclerosis / Q000473:pathology; D013122:Spinal Diseases / Q000000981:diagnostic imaging / Q000473:pathology*