Syngeneic consecutive rat spleen transplantation bearing infantile testis.
Seventy-seven Lewis adult rats received autologous testicular implants in the spleen. These spleens were retransplanted in a consecutive transplant fashion as we described earlier. Some were observed as long as 26 to 27 months. Although earlier splenic-testicular transplants showed benign granulosa cell tumors, some of the long-term follow-ups showed a seminoma-like transformation.
Lee
S
S
Pathology Department, San Diego Microsurgical Institute, La Jolla, CA 92038, USA.
Yoo
C H
CH
Hong
I C
IC
Bai
S
S
Nam
S
S
Lee
D
D
Sileshi
B
B
Nozawa
M
M
Niewiadomski
S
S
Fazi
M
M
Wolf
P
P
Tatum
T
T
Gittes
R F
RF
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D008297:Male; D008866:Microsurgery; D051381:Rats; D011917:Rats, Inbred Lew; D018239:Seminoma / Q000473:pathology*; D013154:Spleen / Q000473:pathology / Q000637:transplantation*; D013736:Testicular Neoplasms / Q000473:pathology*; D013737:Testis / Q000473:pathology / Q000637:transplantation*; D014185:Transplantation, Isogeneic