Clinical evaluation of patients with idiopathic juvenile osteoporosis.
The aim of this study is to evaluate the occurrence of idiopathic juvenile osteoporosis by clinical, radiographic and biochemical methods in 7 patients aged 10 years to 18 years. The prevailing clinical symptoms included pain in the lower limbs and spine, gait disturbances and weak muscles; confirmed fractures were seen in four out of seven patients. In all patients, bone mineral density was determined by dual-energy X-ray absorptiometry and calcium-phosphorus metabolism assays were performed. Clinical evaluation of our patients revealed a wide variety of classic clinical symptoms, and also radiographic and biochemical features. In this complex evaluation, we can distinguish two types of disease occurrence, mild and acute.
Chlebna-Sokół
D
D
Department of Pediatric Propedeutics, Medical University of Lódź, Poland.
Loba-Jakubowska
E
E
Sikora
A
A
D015502:Absorptiometry, Photon; D000208:Acute Disease; D000293:Adolescent; D000469:Alkaline Phosphatase / Q000378:metabolism; D015992:Body Mass Index; D015519:Bone Density; D002118:Calcium / Q000378:metabolism; D002648:Child; D003401:Creatine; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology; D005684:Gait; D006801:Humans; D008274:Magnesium / Q000378:metabolism; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis* / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D010146:Pain / Q000209:etiology; D010281:Parathyroid Hormone / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism; D011627:Puberty; D012720:Severity of Illness Index
D010281:Parathyroid Hormone; D010758:Phosphorus; D000469:Alkaline Phosphatase; D008274:Magnesium; D003401:Creatine; D002118:Calcium