3-Aryl-2-oxazolidinones through the palladium-catalyzed N-arylation of 2-oxazolidinones.
[reaction: see text] 3-Aryl-2-oxazolidinones are obtained in good yields through the palladium-catalyzed N-arylation of 2-oxazolidinones with aryl bromides. The nature of aryl bromides, phosphine ligands, bases, and solvents strongly affects the reaction outcome.
Cacchi
S
S
Dipartimento di Studi di Chimica e Tecnologia delle Sostanza Biologicamente Attive, Università degli Studi La Sapienza, P.le A. Moro 5, 00185 Rome, Italy. sandro.cacchi@uniroma1.it
Fabrizi
G
G
Goggiamani
A
A
Zappia
G
G
D000478:Alkylation; D002384:Catalysis; D007202:Indicators and Reagents; D010080:Oxazoles / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
D007202:Indicators and Reagents; D010080:Oxazoles; D010165:Palladium