Mapping of the rat glypican genes.
The glypicans compose a family of glycosylphosphatidylinositol (GPI)-anchored heparan sulfate proteoglycans that play a role in the control of cell division and growth regulation. So far, six members (GPC1-6) of this family are known in vertebrates. The rat glypican gene 3 (Gpc3) was previously assigned to chromosome Xq36 (Shen et al., 1997). Using standard and radiation cell hybrids, we localized the five other rat glypican genes.
Szpirer
C
C
Institut de Biologie et de Médecine Moléculaires, Université Libre de Bruxelles, Rue Profs Jeener et Brachet 12, B-6041 Gosselies, Belgium. cszpirer@dbm.ulb.ac.be
Szpirer
J
J
Rivière
M
M
Van Vooren
P
P
Veugelers
M
M
David
G
G
D000818:Animals; D002875:Chromosomes / Q000235:genetics; D003001:Cloning, Molecular; D020224:Expressed Sequence Tags; D019812:Heparan Sulfate Proteoglycans / Q000235:genetics*; D051379:Mice; D021101:Radiation Hybrid Mapping; D051381:Rats
D019812:Heparan Sulfate Proteoglycans