[Effect of Shenmai injection on morphological structure of kidney and peritoneum in rats with 5/6 nephrectomy].
OBJECTIVE
To study the protective effect of Shenmai injection (SMI) on kidney and peritoneum in rats with 5/6 nephrectomy.


METHODS
By using cell morphological quantification, light microscopy and scanning electron microscopy, the morphological structure changes of peritoneum and kidney in rats with 5/6 nephrectomy caused chronic renal failure model after the intramuscular or intraperitoneal injection of SMI were observed.


RESULTS
The SMI injection could relieve glomerular sclerosis, promote the recovery and proliferation of injured peritoneal mesothelial cell. The effect of the SMI intraperitoneal injection is better than that intramuscular of injection.


CONCLUSIONS
The SMI has the protective effect on kidney and peritoneum in rats with 5/6 nephrectomy.
He
Z
Z
Institute of Integrated Traditional Chinese and Western Medicine, Hunan Medical University, Changsha 410008.
Yang
X
X
Zhang
S
S
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D007668:Kidney / Q000473:pathology* / Q000648:ultrastructure; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy*; D008297:Male; D009392:Nephrectomy / Q000379:methods; D010530:Peritoneal Dialysis / Q000379:methods; D010537:Peritoneum / Q000473:pathology* / Q000648:ultrastructure; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal