title: [Morphological study of CD3+ dendritic epidermal T cells in human skin and scar].
abstract: OBJECTIVE
  To investigate the CD3/TCR-bearing T cell in the epidermis and explore the influence of the dendritic epidermal T cells on regeneration and differentiation of epidermal cells.
  
  
  METHODS
  The CD3/TCR-bearing T cells in epidermis of human skin and cicatrix were examined by means of histomorphology and immunohistochemistry.
  
  
  RESULTS
  It was found that the density of CD3/TCR-bearing T cells in human skin and scar tissue had great dissimilarity. CD3+ dendritic epidermal T cells increased in hyperplastic scar. Such result was not observed in atrophic scar.
  
  
  CONCLUSIONS
  Our findings indicate CD3+ dendritic epidermal T cells regulate the generation and differentiation of epidermal cells. CD3+ dendritic epidermal T cells may play an important role in the maintenance of the morphology of epidermal tissue.
authors.affiliation: Plastic Surgery Institute, Chinese Academy of Medical Sciences, Beijing 100041.
authors.forename: Z
authors.initials: Z
authors.lastname: Cai
authors.forename: H
authors.initials: H
authors.lastname: Ma
authors.forename: R
authors.initials: R
authors.lastname: Zhao
mesh_terms: D000328:Adult; D017252:CD3 Complex / Q000378:metabolism; D002921:Cicatrix / Q000276:immunology / Q000473:pathology; D017439:Cicatrix, Hypertrophic / Q000276:immunology / Q000473:pathology*; D004817:Epidermis / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017260:Receptor-CD3 Complex, Antigen, T-Cell / Q000378:metabolism*; D012867:Skin / Q000276:immunology / Q000473:pathology*; D013601:T-Lymphocytes / Q000473:pathology*
chemical_list: D017252:CD3 Complex; D017260:Receptor-CD3 Complex, Antigen, T-Cell