Arrhythmias in neurofibromatosis. A case report and review of the literature.
Patients with neurofibromatosis have a higher incidence of anatomic cardiac abnormalities. However, there is little data regarding incidence of arrhythmias in this population. It is known that these patients have a higher mortality than the normal population, and it is possible that some deaths may be due to preventable causes such as cardiac arrhythmias. We report a patient with neurofibromatosis who was treated for a refractory seizure disorder for 8 years. However, video/EEG monitoring demonstrated that the patient had recurrent syncopal seizures secondary to sinus node dysfunction. Complete resolution of symptoms occurred after a permanent pacemaker implantation. We believe this is the first reported case of sinus node dysfunction associated with neurofibromatosis.
Verma
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S
Section of Cardiology, Medical College of Georgia, Augusta, GA 30912-3105, USA.
Ahmed
S
S
Gudapati
S B
SB
King
D W
DW
Meador
K J
KJ
Ahmed
R
R
D000328:Adult; D003937:Diagnosis, Differential; D004562:Electrocardiography; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000209:etiology*; D005260:Female; D006801:Humans; D017253:Neurofibromatoses / Q000175:diagnosis*; D010138:Pacemaker, Artificial; D012804:Sick Sinus Syndrome / Q000175:diagnosis* / Q000628:therapy; D013575:Syncope / Q000209:etiology*; D014741:Video Recording