[Efficacy of quinagolide in the treatment of a patient with hypophyseal resistance to thyroid hormones].
The pituitary resistance to thyroid hormones (PRTH) is not very frequent and well-known entity, their treatment it continues being topic of controversy. In this work we have evaluated the quinagolida effectiveness in the treatment of it unites patient with (PRTH). The relationship among thyroid stimulating hormone (TSH) and free triiodothyronine (FT3) it was used as marker of the thyroid resistance and of the response to the treatment. The concentrations of TSH and FT3 were normalized after adding quinagolida to methimazole. These results suggest that the quinagolida could be an useful drug in the treatment of this pathology, next to the classic treatments.
De Luis
D A
DA
Sec. Endocrinología y Nutrición, Hospital Río Hortega, Instituto Endocrinología y Nutrición, Facultad de Medicina, Valladolid, Departamento Endocrinología, Hospital Ramón y Cajal, Madrid.
Lahera
M
M
Botella
J I
JI
Valero
M A
MA
Varela
C
C
D000328:Adult; D000634:Aminoquinolines / Q000627:therapeutic use*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D012074:Remission Induction; D018382:Thyroid Hormone Resistance Syndrome / Q000188:drug therapy*
D000634:Aminoquinolines; D018491:Dopamine Agonists; C046650:quinagolide