Characterization and chromosomal localization of five canine ATOX1 pseudogenes.
We have isolated six ATOX1 loci from the canine genome in BAC clones. Sequence analysis showed that five of these clones correspond to processed pseudogenes. Fluorescent in situ hybridization allowed us to map the genuine ATOX1 gene to CFA4q24-->q31 and the ATOX1 pseudogenes to CFA19q13.1, CFA4q24-->q31, CFA18q24-->q25, CFA9q22.1 -->q22.2 and CFA20q11-->q12.
van de Sluis
B
B
Department of Medical Genetics, University Medical Center Utrecht, Utrecht University, WKZ, Lundlaan 6, 3584 EA Utrecht, The Netherlands.
Nanji
M S
MS
Breen
M
M
Pearson
P L
PL
Oost
B A
BA
Cox
D W
DW
Wijmenga
C
C
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics*; D027682:Cation Transport Proteins; D022202:Chromosomes, Artificial, Bacterial; D003001:Cloning, Molecular; D004285:Dogs / Q000235:genetics*; D015723:Gene Library; D017404:In Situ Hybridization, Fluorescence; D018832:Molecular Chaperones; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000737:chemistry / Q000235:genetics*; D020161:Physical Chromosome Mapping; D011544:Pseudogenes / Q000235:genetics*; D016415:Sequence Alignment
D002352:Carrier Proteins; D027682:Cation Transport Proteins; D018832:Molecular Chaperones; D009479:Neuropeptides