title: An introduction to peptide nucleic acid.
abstract: Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the behaviour of DNA and binds complementary nucleic acid strands. The unique chemical, physical and biological properties of PNA have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.
authors.affiliation: Panum Institute, DK-2200 Copenhagen N, Denmark.
authors.forename: P E
authors.initials: PE
authors.lastname: Nielsen
authors.forename: M
authors.initials: M
authors.lastname: Egholm
mesh_terms: D004247:DNA; D015342:DNA Probes / Q000235:genetics / Q000378:metabolism; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D020135:Peptide Nucleic Acids / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D013696:Temperature
chemical_list: D015342:DNA Probes; D020135:Peptide Nucleic Acids; C051802:triplex DNA; D004247:DNA