title: Mineral trioxide aggregate repair of lateral root perforations.
abstract: This study was conducted to observe the healing process of intentional lateral root perforation repaired with mineral trioxide aggregate (MTA). Forty-eight root canals of dogs' teeth were instrumented and filled. After partial removal of the filling, an intentional perforation was made with a bur in the lateral area of the root. The perforations were repaired with MTA or Sealapex (control group). Histological analysis occurred 30 and 180 days after treatment. Results showed no inflammation and deposition of cementum over MTA in the majority of the specimens. In the 180-day period, Sealapex exhibited chronic inflammation in all the specimens and slight deposition of cementum over the material in only three cases. In conclusion, MTA exhibited better results than the control group.
authors.affiliation: Faculdade de Odontologia de Araçatuba, UNESP, São Paulo, Brazil.
authors.forename: R
authors.initials: R
authors.lastname: Holland
authors.forename: J A
authors.initials: JA
authors.lastname: Filho
authors.forename: V
authors.initials: V
authors.lastname: de Souza
authors.forename: M J
authors.initials: MJ
authors.lastname: Nery
authors.forename: P F
authors.initials: PF
authors.lastname: Bernabé
authors.forename: E D
authors.initials: ED
authors.lastname: Junior
mesh_terms: D017607:Aluminum Compounds / Q000627:therapeutic use*; D000818:Animals; D017610:Calcium Compounds / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000627:therapeutic use; D003238:Connective Tissue / Q000473:pathology; D003739:Dental Cementum / Q000473:pathology; D003786:Dental Pulp Cavity / Q000293:injuries* / Q000473:pathology; D004285:Dogs; D004338:Drug Combinations; D005500:Follow-Up Studies; D015726:Giant Cells / Q000473:pathology; D007249:Inflammation; D008264:Macrophages / Q000473:pathology; D010087:Oxides / Q000627:therapeutic use*; D010513:Periodontal Ligament / Q000473:pathology; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D018915:Root Canal Preparation / Q000295:instrumentation; D012459:Salicylates / Q000627:therapeutic use; D017640:Silicates / Q000627:therapeutic use*; D014092:Tooth Root / Q000293:injuries; D014945:Wound Healing
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D012459:Salicylates; D017640:Silicates; C086631:mineral trioxide aggregate; C055601:Sealapex; D002126:Calcium Hydroxide