title: Visual loss in childhood.
abstract: An eight-year-old girl presented with vision loss and optic atrophy. Neuro-imaging revealed a sellar mass, which when biopsied proved to be a chiasmatic/hypothalamic glioma. The differential diagnosis of a sellar mass in childhood is discussed, and the presentation and management of chiasmatic/hypothalamic gliomas is reviewed.
authors.affiliation: Division of Neuro-Ophthalmology, Department of Neurology, The Children's Hospital of Philadelphia, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: G T
authors.initials: GT
authors.lastname: Liu
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005910:Glioma / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007029:Hypothalamic Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D009896:Optic Atrophy / Q000175:diagnosis / Q000209:etiology; D009897:Optic Chiasm / Q000473:pathology*; D019574:Optic Nerve Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D014786:Vision Disorders / Q000175:diagnosis* / Q000209:etiology; D014792:Visual Acuity; D058609:Visual Field Tests; D014794:Visual Fields
chemical_list: D000970:Antineoplastic Agents