title: Hypothalamic encephalitis with bradycardia.
abstract: A 74-year-old man developed fever, somnolence, hyponatremia, and life-threatening sinus bradycardia for three weeks. He showed a slight elevation of lymphocyte count and protein level in the cerebrospinal fluid. A brain CT scan revealed a diffuse low density area around the hypothalamus which was identified as a high intensity signal by flair MR imaging. Marked sinus bradycardia developed with no abnormality in the echocardiograph or cardiac enzymes. Over the next 6 weeks he became alert and normal sinus rhythm resumed. The results of endocrine tests were compatible with hypothalamic insufficiency with partial hypopituitarism and the syndrome of inappropriate secretion of ADH.
authors.affiliation: Department of Medicine, Shinshu University School of Medicine, Matsumoto.
authors.forename: S
authors.initials: S
authors.lastname: Ishikawa
authors.forename: H
authors.initials: H
authors.lastname: Aoki
authors.forename: C
authors.initials: C
authors.lastname: Akahane
authors.forename: H
authors.initials: H
authors.lastname: Shimada
authors.forename: Y
authors.initials: Y
authors.lastname: Takei
authors.forename: Y
authors.initials: Y
authors.lastname: Ichinose
authors.forename: S
authors.initials: S
authors.lastname: Ikeda
mesh_terms: D000368:Aged; D001919:Bradycardia / Q000097:blood / Q000209:etiology*; D004660:Encephalitis / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D006728:Hormones / Q000097:blood*; D006801:Humans; D007027:Hypothalamic Diseases / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D007177:Inappropriate ADH Syndrome / Q000150:complications; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D006728:Hormones