title: Metachronous bilateral submandibular gland metastases from carcinoma of the breast.
abstract: Metastases to the salivary glands from distant neoplasms are unusual, with most reported cases involving the parotid gland. Metastatic deposits in the submandibular gland are extremely rare with bilateral involvement not previously reported. We present the case of a patient with advanced breast carcinoma who has had metachronous involvement of both submandibular glands and review the literature on this subject.
authors.affiliation: Department of Otolaryngology, Raigmore Hospital, Inverness, Scotland. angus@guscain.freeserve.co.uk
authors.forename: A J
authors.initials: AJ
authors.lastname: Cain
authors.forename: J
authors.initials: J
authors.lastname: Goodlad
authors.forename: S W
authors.initials: SW
authors.lastname: Denholm
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000556:secondary*; D000328:Adult; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000737:chemistry / Q000556:secondary*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D011960:Receptors, Estrogen / Q000032:analysis; D019572:Retinal Neoplasms / Q000556:secondary; D013125:Spinal Neoplasms / Q000556:secondary; D013365:Submandibular Gland Neoplasms / Q000737:chemistry / Q000556:secondary*
chemical_list: D011960:Receptors, Estrogen