Tracing the lineage of tracing cell lineages.
The study of cell lineages has been, and remains, of crucial importance in developmental biology. It requires the identification of a cell or group of cells and of all of their descendants during embryonic development. Here, we provide a brief survey of how different techniques for achieving this have evolved over the last 100 years.
Stern
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Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. c.stern@ucl.ac.uk
Fraser
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D000818:Animals; D015509:Developmental Biology / Q000266:history / Q000639:trends; D005314:Embryonic and Fetal Development; D049673:History, 20th Century; D009024:Morphogenesis; D009420:Nervous System / Q000166:cytology / Q000196:embryology*