title: Insulin resistance and beta-cell dysfunction as therapeutic targets in type 2 diabetes.
authors.affiliation: Diabetes and Endocrinology, Southampton General Hospital, Southampton SO16 6YD, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Evans
authors.forename: A J
authors.initials: AJ
authors.lastname: Krentz
mesh_terms: D003920:Diabetes Mellitus / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000503:physiopathology* / Q000628:therapy*; D015195:Drug Design; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000378:metabolism / Q000502:physiology*; D007333:Insulin Resistance; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000378:metabolism / Q000503:physiopathology*; D009765:Obesity / Q000503:physiopathology
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin