title: Accuracy of intravascular ultrasound for diameter measurement of phantom arteries.
abstract: BACKGROUND
  Uniplanar quantitative angiography (QA) is the standard method for measuring vessel diameter during surgical and endovascular procedures. Intravascular ultrasound (IVUS), a relatively new technology, is another means of obtaining this measurement. This study was designed to validate the accuracy of these two modalities by comparing each to direct caliper measurement, the gold standard, using phantom femoral artery segments (PAS).
  
  
  METHODS
  PAS diameter was measured with a 12.5-MHz mechanically rotating IVUS catheter (Boston Scientific Corp.) and QA (OEC Corp.) was compared to the direct caliper measurement (Mitutoyo Corp.) at 60 different locations within PAS. At each location minimal lumen diameter and perpendicular lumen diameter were measured and their mean was calculated. The intraclass correlation coefficients (ICCC) between direct caliper measurement and IVUS and uniplanar and biplanar angiography were calculated. Fisher's Z transformation was used to compare the correlation coefficients.
  
  
  RESULTS
  The ICCC for IVUS was 0.89. The ICCCs for uniplanar and biplanar angiography were 0.73 and 0.82, respectively. IVUS correlated more closely with direct caliper measurement than uniplanar and biplanar angiography (P = 0.00008, 0.02) Biplanar angiography correlated more closely with direct caliper measurement than uniplanar angiography (P = 0.04).
  
  
  CONCLUSIONS
  IVUS more accurately measures lumen diameter than uniplanar or biplanar angiography. Diameter measurement with biplanar angiography is more accurate than uniplanar angiography.
authors.affiliation: Department of Surgery, SUNY-Downstate Medical Center, Brooklyn, New York 11203, USA.
authors.forename: B Z
authors.initials: BZ
authors.lastname: Cooper
authors.forename: J D
authors.initials: JD
authors.lastname: Kirwin
authors.forename: T F
authors.initials: TF
authors.lastname: Panetta
authors.forename: F M
authors.initials: FM
authors.lastname: Weinreb
authors.forename: J A
authors.initials: JA
authors.lastname: Ramirez
authors.forename: J G
authors.initials: JG
authors.lastname: Najjar
authors.forename: S B
authors.initials: SB
authors.lastname: Blattman
authors.forename: W
authors.initials: W
authors.lastname: Rodino
authors.forename: M
authors.initials: M
authors.lastname: Song
mesh_terms: D000792:Angiography / Q000379:methods / Q000592:standards; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D018084:Ultrasonography, Interventional / Q000379:methods* / Q000592:standards*; D014656:Vascular Surgical Procedures