title: Biomimetic apatite formation on polyethylene photografted with vinyltrimethoxysilane and hydrolyzed.
abstract: A photografting technique to produce functional groups of silanol able to induce apatite nucleation was attempted on polyethylene substrate for biomimetic formation of bone-mineral-like apatite layer on its surface. The polyethylene surface was subjected to vapor-phase photografting of vinyltrimethoxysilane and subsequently to hydrolysis. The photografting formed methoxysilyl groups on the polyethylene substrate, which was changed into silanol groups successively by the hydrolysis in a hydrochloric solution. The polyethylene modified in this way formed a dense and homogeneous bone-mineral-like apatite layer in a solution with ion concentrations 1.5 times that of human blood plasma. This result indicates that the biomimetic process in combination with a polymeric grafting technique might provide a homogeneous bone-mineral-like apatite coating even on polymer fibers to be woven into an apatite-polymer composite with three-dimensional structure analogous to that of natural bone.
authors.affiliation: Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Japan. kim@sung7.kuic.kyoto-u.ac.jp
authors.forename: H M
authors.initials: HM
authors.lastname: Kim
authors.forename: M
authors.initials: M
authors.lastname: Uenoyama
authors.forename: T
authors.initials: T
authors.lastname: Kokubo
authors.forename: M
authors.initials: M
authors.lastname: Minoda
authors.forename: T
authors.initials: T
authors.lastname: Miyamoto
authors.forename: T
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D001031:Apatites / Q000138:chemical synthesis* / Q000737:chemistry; D018786:Bone Substitutes / Q000138:chemical synthesis* / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis / Q000737:chemistry; D006801:Humans; D006868:Hydrolysis; D066298:In Vitro Techniques; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010777:Photochemistry; D020959:Polyethylene / Q000737:chemistry; D012821:Silanes / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D001031:Apatites; D018786:Bone Substitutes; D020099:Coated Materials, Biocompatible; D012821:Silanes; D014753:Vinyl Compounds; D020959:Polyethylene; C071717:trimethoxysilane