Hereditary hemochromatosis: a case study and review.
Hereditary hemochromatosis (HH) is a disorder of iron regulation that leads to excessive iron absorption. Over time, the resultant iron overload and deposition in tissue leads to various chronic diseases and premature death. Even though it is the most common genetic disorder among Caucasians in the U.S., hereditary hemochromatosis often goes undetected or unrecognized by healthcare providers. Laboratory tests provide effective, inexpensive means of screening for and confirming hereditary hemochromatosis. The clinical laboratory also plays a key role in hereditary hemochromatosis treatment, reduction of iron stores through therapeutic phlebotomy.
Laudicina
R J
RJ
Clinical Laboratory Science, Hemochromatosis Education and Screening Project, University of North Carolina at Chapel Hill, NC, USA. Rebecca_Laudicina@med.unc.edu
Legrys
V A
VA
D005260:Female; D006432:Hemochromatosis / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D006801:Humans; D008875:Middle Aged