Genital HPV: links to cervical cancer, treatment, and prevention.
Human papillomavirus is one of the most prevalent sexually transmitted viruses. It consists of over 230 different subtypes and infects the squamous epithelial cells in humans producing cutaneous, mucosal, and epidermodysplasia verruciformis type infections. There are several risk factors for human papillomavirus infections. These include a sexually active life-style beginning at a young age, having multiple lifetime sex partners, having sex with a partner with genital warts, and long term oral contraceptive use. Approximately 80% of sexually active individuals acquire the virus in their lifetime. Clinical and laboratory detection of the virus consists of macroscopic, serologic, and molecular techniques. Although removal of the lesions is preferable, treatment of human papillomavirus infections may include cryotherapy, loop electrosurgical excision procedure, laser surgery, and drug therapy. Certain human papillomavirus subtypes, particularly human papillomavirus 16, have been linked to cervical cancer, therefore, prophylactic and therapeutic vaccines are currently being developed to prevent or fight the virus.
Perez
L A
LA
Medical Technologist at Esoterix Infectious Disease Center, San Antonio, TX, USA. lperezwork@hotmail.com
D005260:Female; D006801:Humans; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000150:complications* / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D012307:Risk Factors; D015229:Sexually Transmitted Diseases, Viral / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D014412:Tumor Virus Infections / Q000150:complications* / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy / Q000821:virology*