Experimental demonstration of the possibility to perform shear-driven chromatographic separations in micro-channels.
The possibility to perform shear-driven chromatographic separations in micro-channels is demonstrated, using a novel laser-jet printed microfluidic channel system. The obtained theoretical plate numbers are in fair agreement with the theoretical calculations. Theoretical extrapolations of the separation speeds and detection limits which can be achieved when further miniaturizing the current system are presented as well.
Desmet
G
G
Vrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium. gedesmet@vub.ac.be
Vervoort
N
N
Clicq
D
D
Baron
G V
GV
D002845:Chromatography / Q000295:instrumentation*; D004867:Equipment Design; D008855:Microscopy, Electron, Scanning