title: [Effect of cloned DNA fragment from Streptomyces chrysomallus No.2 on metabolism in Streptomyces strains].
abstract: The effects on cloned DNA fragment carrying an actinomycin resistance determinant on physiological processes in streptomyces strains with various potencies in producing this antibiotic, their inactive mutants, and model strain of Streptomyces lividans 66 were studied. This fragment was shown to modulate bacterial resistance to actinomycin and biosynthesis of antibiotics.
authors.affiliation: M. V. Lomonosov Moscow State University.
authors.forename: T Iu
authors.initials: TIu
authors.lastname: Novozhilova
authors.forename: T A
authors.initials: TA
authors.lastname: Alekhova
mesh_terms: D003001:Cloning, Molecular; D004269:DNA, Bacterial / Q000235:genetics*; D003609:Dactinomycin; D024881:Drug Resistance, Bacterial; D015964:Gene Expression Regulation, Bacterial; D010957:Plasmids; D011995:Recombination, Genetic; D013302:Streptomyces / Q000235:genetics* / Q000378:metabolism; D014162:Transfection
chemical_list: D004269:DNA, Bacterial; D003609:Dactinomycin
vernacular_title: Vliianie klonirovannogo fragmenta DNK Streptomyces chrysomallus #2 na metabolizm riada shtammov streptomitsetov.