[Familial gout and nephropathy in a young woman. Report of one case].
We report a 29 years old woman with a chronic tophaceous gout, whose disease started at the age of 18. On clinical examination, the blood pressure was elevated. The laboratory assessment showed a serum uric acid of 15 mg/dl, a urinary uric acid of 155 mg/24 h, a creatinine clearance of 59 ml/min/1.73 m2 and a uric acid excretion fraction off 1.3% (normal 7 to 12%). The clinical and laboratory features of this patient suggest the diagnosis of a familial juvenile gouty nephropathy.
Badilla
A
A
Departamento de Reumatología Hospital San Juan de Dios, Santiago de Chile. rbadilla@rdc.cl
Rojas
C
C
D000328:Adult; D000493:Allopurinol / Q000627:therapeutic use; D005260:Female; D005817:Genetic Counseling; D006073:Gout / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000235:genetics*; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000150:complications / Q000235:genetics*; D014527:Uric Acid / Q000097:blood*
D006074:Gout Suppressants; D014527:Uric Acid; D000493:Allopurinol
Gota familiar y nefropatía en una mujer joven. Caso clínico.