title: Noncovalently functionalized dendrimers as recyclable catalysts.
abstract: The efficient reversible functionalization of the periphery of urea adamantyl poly(propylene imine) dendrimers with catalytic sites using noncovalent interactions is described. Phosphine ligands equipped with urea acetic groups, a binding motive complementary to that of the dendrimer host, have been prepared and assembled to the dendrimer support. The resulting supramolecular complex has been used as a multidentate ligand system in the palladium-catalyzed allylic amination reaction in a batch process and in a continuous-flow membrane reactor. We found that the activity and selectivity of the dendrimeric complex is similar to that of the monomer complex, which indicates that the catalytic centers act as independent sites. The size of the supramolecular system is sufficiently large and the binding of the guests is strong enabling a good separation of the catalyst components from the reaction mixture using nanofiltration techniques.
authors.affiliation: Institute of Molecular Chemistry, University of Amsterdam, Nieuwe Achtergracht 166, 1018 WV Amsterdam, The Netherlands.
authors.forename: D
authors.initials: D
authors.lastname: de Groot
authors.forename: B F
authors.initials: BF
authors.lastname: de Waal
authors.forename: J N
authors.initials: JN
authors.lastname: Reek
authors.forename: A P
authors.initials: AP
authors.lastname: Schenning
authors.forename: P C
authors.initials: PC
authors.lastname: Kamer
authors.forename: E W
authors.initials: EW
authors.lastname: Meijer
authors.forename: P W
authors.initials: PW
authors.lastname: van Leeuwen