title: Effects of decreasing the frequency of ventilator circuit changes to every 7 days on the rate of ventilator-associated pneumonia in a Beijing hospital.
abstract: BACKGROUND
  We investigated whether decreasing ventilator circuit changes from every 2 days to every 7 days would impact ventilator-associated pneumonia rates at our institution.
  
  
  METHODS
  All mechanically ventilated patients at Peking Union Medical College Hospital were studied over a 21 month period. From March 1998 to February 1999, ventilator circuits were changed every 2 days, and from June through December 1999, ventilator circuits were changed every 7 days. Nosocomial pneumonia was identified using the criteria of the Centers for Disease Control.
  
  
  RESULTS
  In the 2-day-change group, there were 2,277 ventilator-patient days and 38 patients developed pneumonia, resulting in a pneumonia rate of 16.7 cases per 1,000 ventilator days. The 7-day-change group accumulated 972 ventilator days and 8 patients contracted pneumonia, resulting in a pneumonia rate of 8.2 cases per 1,000 ventilator days. The pneumonia rate was significantly lower in the 7-day-change group (p = 0.007). To standardize for seasonal variability, we compared results from the same seasonal time frames (June to December 1998 for the 2-day-change group, and June to December 1999 for the 7-day-change group), and obtained similar findings: during those periods, pneumonia rates were 24.2 cases per 1,000 ventilator days for the 2-day-change group and 8.9 cases per 1,000 ventilator days for the 7-day-change group (p = 0.001).
  
  
  CONCLUSIONS
  A circuit change interval of 7 days had a lower risk of ventilator-associated pneumonia than a 2-day change interval. Therefore, ventilator circuits can be safely changed every 7 days in our setting.
authors.affiliation: Respiratory Care Center, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. janet_han2000@hotmail.com
authors.forename: J N
authors.initials: JN
authors.lastname: Han
authors.forename: Y P
authors.initials: YP
authors.lastname: Liu
authors.forename: S
authors.initials: S
authors.lastname: Ma
authors.forename: Y J
authors.initials: YJ
authors.lastname: Zhu
authors.forename: S H
authors.initials: SH
authors.lastname: Sui
authors.forename: X J
authors.initials: XJ
authors.lastname: Chen
authors.forename: D M
authors.initials: DM
authors.lastname: Luo
authors.forename: A B
authors.initials: AB
authors.lastname: Adams
authors.forename: J J
authors.initials: JJ
authors.lastname: Marini
mesh_terms: D003428:Cross Infection / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000209:etiology / Q000401:mortality / Q000517:prevention & control*; D012121:Respiration, Artificial / Q000009:adverse effects / Q000295:instrumentation*; D012621:Seasons; D012122:Ventilators, Mechanical