[Major mRNP proteins in the structural organization and function of mRNA in eukaryotic cells].
The properties of two universal major proteins of cytoplasmic mRNP, p50 and the poly(A)-binding protein (PABP), are summarized. Their roles in formation of polyribosomal and free inactive mRNP are considered, with the focus on the authors' studies of p50. The parts these mRNP proteins play in translation regulation, stability, and localization of mRNA are described, and the the possible mechanisms of their function are discussed.
Ovchinnikov
L P
LP
ovchinn@vega.protres.ru
Skabkin
M A
MA
Ruzanov
P V
PV
Evdokimova
V M
VM
D000818:Animals; D005057:Eukaryotic Cells; D006801:Humans; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000737:chemistry / Q000502:physiology*; D012261:Ribonucleoproteins / Q000737:chemistry / Q000502:physiology*; D012270:Ribosomes / Q000502:physiology
D012333:RNA, Messenger; D012261:Ribonucleoproteins; C026452:messenger ribonucleoprotein
Mazhornye belki mRNP v strukturnoĭ organizatsii i funktsionirovanii mRNK v kletkakh éukariot.