Acetazolamide poisoning in a toddler.
Acetazolamide ingestion and its sequelae have not been previously reported in children. A 12-month-old girl, weighing 10 kg, developed metabolic acidosis following ingestion of between 500 and 1250 mg of acetazolamide. The maximum base deficit recorded was 11.6. She was treated with sodium bicarbonate and recovered completely. Accidental poisoning should be included in the differential diagnosis of a child presenting with metabolic acidosis.
Baer
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Royal Children's Hospital, Herston, Queensland, Australia.
Reith
D M
DM
D000086:Acetazolamide / Q000506:poisoning*; D000138:Acidosis / Q000139:chemically induced* / Q000188:drug therapy; D002257:Carbonic Anhydrase Inhibitors / Q000506:poisoning*; D005260:Female; D006801:Humans; D007223:Infant; D017693:Sodium Bicarbonate / Q000627:therapeutic use
D002257:Carbonic Anhydrase Inhibitors; D017693:Sodium Bicarbonate; D000086:Acetazolamide