Diffuse liver lesions among the general population of western Siberia.
The study was aimed at ascertaining the prevalence of diffuse liver lesions and associated factors in the general population of Novosibirsk, Western Siberia. A representative sample of 362 men and 870 women aged 25-64 years was investigated using ultrasound examination and blood tests for liver-derived enzymes (AST, ALT, GGT). Diffuse liver lesions (DLL) were detected in 42.8% of males and 18.7% of females. A significant association was found between DLL and elevated levels of liver enzymes. In conclusion, the prevalence of chronic liver disease is relatively frequent in the unselected urban population.
Kurilovich
S A
SA
Institute of Internal Medicine, Novosibirsk, Russia. ksa@itr.nsu.ru
Reshetnikov
O V
OV
Rybiakov
A N
AN
Shakhmatov
S G
SG
Malytina
S K
SK
Ivanova
M V
MV
D000328:Adult; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000201:enzymology / Q000473:pathology*; D008107:Liver Diseases / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012800:Siberia / Q000453:epidemiology; D014463:Ultrasonography