title: [A case of Coxiella burnetii pneumonia in an adult].
abstract: A 49-year-old man visited our hospital complaining of a continuous high-grade fever and cough which had appeared during his stay in Indonesia. He was admitted on the same day because his laboratory data showed marked inflammatory changes and his chest radiograph revealed an infiltrative shadow in the right upper lung field. Initial treatment with beta-lactams was not effective and both his symptoms and his chest radiograph worsened. However, treatment with erythromycin clearly had an effect. Then, we carried out several tests for detection of atypical pathogens including Mycoplasma and Chlamydia. Finally, the case was diagnosed as one of Coxiella burnetii pneumonia because the DNA of C. burnetii was detected from his sera and seroconversion of C. burnetii--specific antibody was observed among paired serum samples. C. burnetii is one of the most commonly recognized pathogens among community-acquired pneumonias in Western countries, but in Japan, reports of community-acquired C. burnetii pneumonia have been rare. This difference may be due to the features of Q fever, in which there are large differences in frequency and form from country to country and among areas of the same country. Surveillance of C. burnetii pneumonia in Japan and different area will be required.
authors.affiliation: Department of Internal Medicine and Surgery, Kurashiki Daiichi Hospital.
authors.forename: N
authors.initials: N
authors.lastname: Miyashita
authors.forename: H
authors.initials: H
authors.lastname: Fukano
authors.forename: H
authors.initials: H
authors.lastname: Hara
authors.forename: F
authors.initials: F
authors.lastname: Hara
authors.forename: T
authors.initials: T
authors.lastname: Nakajima
authors.forename: Y
authors.initials: Y
authors.lastname: Niki
authors.forename: T
authors.initials: T
authors.lastname: Matsushima
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D016997:Coxiella burnetii / Q000302:isolation & purification; D004917:Erythromycin / Q000627:therapeutic use; D006801:Humans; D007214:Indonesia; D007564:Japan; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D011778:Q Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D014195:Travel; D015047:Zoonoses
chemical_list: D000900:Anti-Bacterial Agents; D004917:Erythromycin