Cholelithiasis in Down's syndrome.
Cholelithiasis is considered uncommon in infancy, childhood, and adolescence. We performed a prospective, controlled study showing that children with Down's syndrome have a significantly higher prevalence of cholelithiasis (4.7%) compared with controls (0.2%). Clinicians should be aware of the risk of gallstones in children with Down's syndrome.
Toscano
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E
Department of Paediatrics, "Federico II" University, Via S. Pansini 5, I-80131 Naples, Italy.
Trivellini
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V
Andria
G
G
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000209:etiology*; D004314:Down Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012307:Risk Factors; D014463:Ultrasonography