title: [Vagotomy in the treatment of acute ulcerations of the stomach complicated by severe hemorrhage].
abstract: It has been found that the intramural nerve apparatus of the stomach is involved in the mechanism of formation of acute gastroduodenal ulcers. Under stress there occurs simultaneous activation of the sympathetic and parasympathetic parts of the vegetative nervous system. The released acetylcholine and noradrenaline influence the corresponding receptors of the target cells which results in hyperproduction of the hydrochloric acid under conditions of hypoxia of the gastric wall and promotes acute ulceration. Conservative hemostatic therapy allows complete hemostasis to be obtained in 95% of patients with acute gastroduodenal ulcers complicated by bleedings. If it fails, the operation of choice is thought to be suturing the source of bleeding supplemented with truncal vagotomy and pyloroplasty.
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Stoíko
authors.forename: A A
authors.initials: AA
authors.lastname: Kurygin
authors.forename: I M
authors.initials: IM
authors.lastname: Musinov
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000818:Animals; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism / Q000473:pathology; D006489:Hemostatic Techniques; D006801:Humans; D007103:Immobilization / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000209:etiology; D010438:Peptic Ulcer Hemorrhage / Q000601:surgery / Q000628:therapy*; D011708:Pylorus / Q000601:surgery; D051381:Rats; D013270:Stomach / Q000294:innervation / Q000473:pathology; D013276:Stomach Ulcer / Q000150:complications* / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D013312:Stress, Physiological / Q000150:complications; D015167:Vagotomy, Truncal
vernacular_title: Vagotomiia v lechenii ostrykh iz"iazvlenií zheludka, oslozhnennykh tiazhelym krovotecheniem.