[Electric stimulation of the brain in patients with hepatocerebral Wilson-Konovalov's degeneration (neuromorphological and neurophysiological analysis)].
36 stereotactic operations were carried out in 27 patients. Either the total lack of hyperkinesis or its significant decrease was found in 17 cases; 5 patients died. There was no correlation between manifestations of hepatocerebral degeneration and relatively normal quantitative characteristics of both cortical and subcortical biopotentials. These potentials are produced on the background of the microstructural changes in the neurons of the same regions. It is suggested that qualitative importance of such biopotentials lies in their exceeding pathologic impulsation, arising hyperkinesis. That was confirmed by the fact, that hyperkinesis eliminates after surgical destruction of the ventrolateral nucleus of the thalamus and the subthalamic structures.
Kozlov
A A
AA
Rokhlina
M L
ML
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000473:pathology / Q000601:surgery*; D004558:Electric Stimulation / Q000379:methods; D006527:Hepatolenticular Degeneration / Q000473:pathology / Q000601:surgery*; D006801:Humans; D006948:Hyperkinesis / Q000175:diagnosis / Q000601:surgery; D012720:Severity of Illness Index; D013238:Stereotaxic Techniques
Elektricheskaia stimuliatsiia mozga pri gepatotserebral'noĭ distrofii Vil'sona-Konovalova (neĭromorfologicheskiĭ i neĭrofiziologicheskiĭ analiz).