[Gallic acid: a potent inhibitor of tetramethylbenzidine peroxidation in aqueous and micellar media].
Gallic acid competitively inhibited 3,3',5,5'-tetramethylbenzidine peroxidation both in 0.01 M phosphate buffer (pH 6.4) (KI 13.3 microM) and in reversed aerosol OT micelles of different hydration degrees dispersed in heptane (KI 21.3 to 29.3 microM). The average number of free radical particles terminated by one inhibitor molecule (f) was estimated to be 1.3 to 1.6 in aqueous buffer solutions and 1.08 to 2.72 in reversed micelles, depending on their hydration.
Karaseva
E I
EI
Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Republic of Belarus 220141.
Nikiforova
T V
TV
Metelitsa
D I
DI
D001560:Benzidines / Q000737:chemistry* / Q000378:metabolism; D005707:Gallic Acid / Q000737:chemistry* / Q000378:metabolism; D007700:Kinetics; D008823:Micelles; D010084:Oxidation-Reduction; D009195:Peroxidase / Q000037:antagonists & inhibitors / Q000737:chemistry
D001560:Benzidines; D008823:Micelles; C021758:3,3',5,5'-tetramethylbenzidine; D005707:Gallic Acid; D009195:Peroxidase
Gallovaia kislota--éffektivnyĭ inhibitor peroksidaznogo okisleniia tetrametilbenzidina v vodnoĭ i mitselliarnoĭ sredakh.