[Biological activity characteristics of the complex of peptide fragments of hemoglobin].
There were studied the influence of hemoglobin peptide complex in different doses on indexes of systemic hemodynamics, ECG and visually cased potentials in healthy animals. In the dose of 10 mg/kg the peptide complex rolonged the time of the course of depolarization and repolarization processes on the miocardial ventricles with the increase of the systolice blood volume. In the dose of 1 mg/kg the introduction of the peptide complex accelerated the conductiong of visual madality stimuli on the specific afferent systems subcortex and cortex divisions of visnal analyzer.
Zaporozhets'
T M
TM
Ukrainian Medical Dental Academy, Health Protection Ministry of Ukraine, Poltava.
Mishchenko
V P
VP
Sanyk
O V
OV
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004553:Electric Conductivity; D004562:Electrocardiography; D005073:Evoked Potentials, Somatosensory / Q000187:drug effects; D005074:Evoked Potentials, Visual / Q000187:drug effects; D006168:Guinea Pigs; D006352:Heart Ventricles / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006454:Hemoglobins / Q000737:chemistry*; D010446:Peptide Fragments / Q000008:administration & dosage*; D013997:Time Factors; D014793:Visual Cortex / Q000187:drug effects
D006454:Hemoglobins; D010446:Peptide Fragments
Kharakterystyka biolohichnoï aktyvnosti kompleksu peptydnykh frahmentiv hemohlobinu.