title: Diffuse liver lesions among the general population of western Siberia.
abstract: The study was aimed at ascertaining the prevalence of diffuse liver lesions and associated factors in the general population of Novosibirsk, Western Siberia. A representative sample of 362 men and 870 women aged 25-64 years was investigated using ultrasound examination and blood tests for liver-derived enzymes (AST, ALT, GGT). Diffuse liver lesions (DLL) were detected in 42.8% of males and 18.7% of females. A significant association was found between DLL and elevated levels of liver enzymes. In conclusion, the prevalence of chronic liver disease is relatively frequent in the unselected urban population.
authors.affiliation: Institute of Internal Medicine, Novosibirsk, Russia. ksa@itr.nsu.ru
authors.forename: S A
authors.initials: SA
authors.lastname: Kurilovich
authors.forename: O V
authors.initials: OV
authors.lastname: Reshetnikov
authors.forename: A N
authors.initials: AN
authors.lastname: Rybiakov
authors.forename: S G
authors.initials: SG
authors.lastname: Shakhmatov
authors.forename: S K
authors.initials: SK
authors.lastname: Malytina
authors.forename: M V
authors.initials: MV
authors.lastname: Ivanova
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000201:enzymology / Q000473:pathology*; D008107:Liver Diseases / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015995:Prevalence; D012800:Siberia / Q000453:epidemiology; D014463:Ultrasonography