Aerosols and devices.
The success of aerosol therapy depends upon the delivery of ample amounts of the drug to appropriate sites in the lung with minimal side effects. Successful aerosol therapy delivery systems must provide sufficient respirable particles or droplets, with minimal loss of the drug. Ultimately, the patient must be able to use the device easily, maintain it, and derive clinical benefit from the drug delivered from the system.
Dolovich
M B
MB
Faculty of Health Science, Department of Medicine, McMaster University, Hamilton, Ontario, Canada. mdolovic@fhs.csu.mcmaster.ca
Fink
J B
JB
D000280:Administration, Inhalation; D000328:Adult; D000336:Aerosols / Q000008:administration & dosage* / Q000494:pharmacology; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage; D001249:Asthma / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D004867:Equipment Design; D004869:Equipment Safety; D006801:Humans; D009330:Nebulizers and Vaporizers / Q000592:standards*; D010316:Particle Size; D012680:Sensitivity and Specificity
D000336:Aerosols; D018927:Anti-Asthmatic Agents