[Mechanism of alcohol action on gastric secretion].
In chronic experiment on dogs (3 dogs with Pavlov's miniature stomach, 3 dogs with Heidenhain's miniature stomach) the mechanism of action of alcohol (8%-150 ml) on gastric secretion was clarified. For this purpose the new inhibitor of gastric secretion--glycopeptide was utilized, which action was preset in laboratory of G.K. Shlygin. Was shown, that in effect of alcohol on gastric secretion take place the complicated mechanism including as a nervous regulation (vagus nerves), and humoral: participation of gastrin and histamine in secretory effect of a stomach, and also immediate effect of ethanol on acid glands.
Vasilevskaia
L S
LS
Skurikhin
I M
IM
Guliev
R R
RR
D000818:Animals; D004285:Dogs; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism; D005750:Gastric Juice / Q000378:metabolism*; D005755:Gastrins / Q000502:physiology; D006632:Histamine / Q000502:physiology; D008297:Male; D013270:Stomach / Q000187:drug effects*; D013997:Time Factors; D014630:Vagus Nerve / Q000187:drug effects / Q000502:physiology
D005755:Gastrins; D000431:Ethanol; D006632:Histamine
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