Differentiation potential of adult stem cells.
In many different adult tissues, stem cells generate new cells either continuously or in response to injury. Such cells were thought to be limited to generating the types of cells normally present in the tissue where the stem cell resides. However, several different stem-cell populations in the adult have been found recently to be capable of generating additional cell types under certain conditions.
Clarke
D
D
Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-171 77, Stockholm, Sweden. dclarke@curis.com
Frisén
J
J
D000818:Animals; D001773:Blood Cells / Q000166:cytology; D001854:Bone Marrow Cells / Q000166:cytology; D001921:Brain / Q000166:cytology; D002454:Cell Differentiation; D019070:Cell Lineage; D005333:Fetus / Q000166:cytology; D022781:Hepatocytes / Q000166:cytology; D006801:Humans; D009132:Muscles / Q000166:cytology; D009474:Neurons / Q000166:cytology; D013234:Stem Cells / Q000166:cytology*