title: [Low molecular weight heparin versus unfractionated heparin in the treatment of deep vein thrombosis].
abstract: BACKGROUND
  Low-molecular-weight heparin (LMWH) are replacing unfractionated heparin (UH) in treatment of deep vein thrombosis (DVP), showing their security and effectiveness.
  
  
  METHODS
  To demonstrate their security and effectiveness a randomized prospective study was realised. It compared UH with LMWH in DP treatment, clinically diagnosed and confirmed with eco-Doppler. The study included 32 patients (21 males and 11 females); 15 received UH in continuos i.v. infusion and 17 sodic dalteparine, with dicumarinic afterwards in every case. The patients were followed for one year.
  
  
  RESULTS
  There were no differences between the two groups of treatment in clinical/radiological effectiveness either in short term nor one year follow up. There were no significative differences in side effects.
  
  
  CONCLUSIONS
  LMWH are as effective and safe as UH for DVT treatment. They also have a more comfortable dosage for the patient, avoiding the i.v. infusion and the coagulation test, which allows treatment at home.
authors.affiliation: Servicios de Medicina Interna, Hematología, Hospital General, Segovia.
authors.forename: J J
authors.initials: JJ
authors.lastname: Moreno-Palomares
authors.forename: R M
authors.initials: RM
authors.lastname: Fisac-Herrero
authors.forename: A
authors.initials: A
authors.lastname: Herrero-Domingo
authors.forename: E M
authors.initials: EM
authors.lastname: Ferreira-Pasos
authors.forename: J
authors.initials: J
authors.lastname: Grasa
authors.forename: D
authors.initials: D
authors.lastname: Reverte-Cejudo
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D017985:Dalteparin / Q000627:therapeutic use; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020246:Venous Thrombosis / Q000188:drug therapy*
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D006493:Heparin; D017985:Dalteparin
vernacular_title: Heparinas de bajo peso molecular frente a heparinas no fraccionadas en el tratamiento de la trombosis venosa profunda.