Evaluating causal relations in neural systems: granger causality, directed transfer function and statistical assessment of significance.
We consider the question of evaluating causal relations among neurobiological signals. In particular, we study the relation between the directed transfer function (DTF) and the well-accepted Granger causality, and show that DTF can be interpreted within the framework of Granger causality. In addition, we propose a method to assess the significance of causality measures. Finally, we demonstrate the applications of these measures to simulated data and actual neurobiological recordings.
Kamiński
M
M
Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton 33431, USA.
Ding
M
M
Truccolo
W A
WA
Bressler
S L
SL
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001921:Brain / Q000166:cytology / Q000502:physiology*; D004569:Electroencephalography; D006801:Humans; D008251:Macaca; D008959:Models, Neurological; D015233:Models, Statistical; D015999:Multivariate Analysis; D009474:Neurons / Q000502:physiology; D012890:Sleep / Q000502:physiology