title: Copper-mediated cross-coupling of functionalized arylmagnesium reagents with functionalized alkyl and benzylic halides.
abstract: [reaction: see text]. Functionalized arylmagnesium halides, prepared via an iodine-magnesium exchange, undergo a smooth cross-coupling reaction with functionalized primary alkyl iodides and benzylic bromides in the presence of CuCN.2LiCl, either in stoichiometric (with trimethyl phosphite as an additive) or catalytic quantities.
authors.affiliation: Ludwig-Maximilians-Universität München, Institut für Organische Chemie, Butenandtstrasse 5-13, Haus F, 81377 München, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Dohle
authors.forename: D M
authors.initials: DM
authors.lastname: Lindsay
authors.forename: P
authors.initials: P
authors.lastname: Knochel