Investigation of the allergenicity of a refined peanut oil-containing topical dermatologic agent in persons who are sensitive to peanuts.
We determined if a topical oil containing 0.01% fluocinolone and refined peanut oil (Derma-Smoothe/FS topical oil), among other ingredients, included materials to which peanut-sensitive individuals were sensitized. No immediate (15-min) or delayed (72-h) skin test reactivity was demonstrated in any of the 14 subjects tested. These results suggest that this refined peanut oil-containing dermatologic preparation is safe to use, even in persons who are sensitive to peanuts.
Yunginger
J W
JW
Department of Pediatric and Adolescent Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
Calobrisi
S D
SD
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D002648:Child; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D021183:Peanut Hypersensitivity / Q000175:diagnosis / Q000276:immunology*; D010938:Plant Oils / Q000008:administration & dosage / Q000009:adverse effects*; D011446:Prospective Studies; D018570:Risk Assessment; D012680:Sensitivity and Specificity
D003879:Dermatologic Agents; D010938:Plant Oils