Hysteroscopic findings in 344 women with recurrent spontaneous abortion.
OBJECTIVE
To evaluate the prevalence of different anatomic factors in women with recurrent spontaneous abortion (RSA).


METHODS
Retrospective analysis over 9 years (Canadian Task Force classification II-2).


METHODS
University hospital-affiliated endoscopic unit.


METHODS
Three hundred forty-four consecutive patients with RSA and 922 controls referred for abnormal uterine bleeding.


METHODS
Diagnostic hysteroscopy.


RESULTS
Major and minor uterine mullerian abnormalities (septate, unicornuate uteri) were found significantly more often in women with RSA than in controls (32% vs 6%, p <0.001). The frequency of acquired uterine anomalies (submucous myomas, polyps) was significantly higher in controls (32% vs 9%, p <0.001). No significant differences were observed between groups in frequency of adhesions (4% vs 2%).


CONCLUSIONS
Major mullerian uterine abnormalities are associated with RSA, and minor uterine anomalies may be correlated with an increased risk of recurrent miscarriage.
Valli
E
E
Department of Obstetrics and Gynaecology, University of Rome Tor Vergata, Ospedale San Giovanni Calibita Fatebenefratelli-Isola Tiberina, 00186 Rome, Italy.
Zupi
E
E
Marconi
D
D
Vaquero
E
E
Giovannini
P
P
Lazzarin
N
N
Romanini
C
C
D000026:Abortion, Habitual / Q000209:etiology*; D000328:Adult; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D011247:Pregnancy; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000150:complications / Q000175:diagnosis; D014599:Uterus / Q000002:abnormalities / Q000473:pathology*