title: Video-assisted thoracoscopic thymectomy in juvenile myasthenia gravis.
abstract: As video-assisted thoracoscopic surgery for thymectomy has been reported to be as effective as traditional open surgical approaches in predominantly adult patients with myasthenia gravis, we applied this procedure to juvenile patients with this condition. Six patients underwent total thymectomy using the video-assisted technique (1997-98). Six patients in whom a median transsternal approach was used (1989-95) formed the comparison group. The two patient groups were similar in terms of age at thymectomy and preoperative clinical severity. There were no serious perioperative complications in either group. Minimum post-thymectomy duration of follow-up in the video-assisted thoracoscopic surgery patients was 2.3 years (mean 2.7 years), with all patients clinically improved over their baseline status. Preliminary results suggest that video-assisted thymectomies are comparably effective to transsternal procedures in treating generalized juvenile myasthenia gravis and can be safely performed in children as young as 20 months of age. In addition, video-assisted surgeries are less invasive than transsternal approaches, significantly shorten the postoperative hospital stay, and have superior cosmetic results.
authors.affiliation: Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
authors.forename: H K
authors.initials: HK
authors.lastname: Kolski
authors.forename: P C
authors.initials: PC
authors.lastname: Kim
authors.forename: J
authors.initials: J
authors.lastname: Vajsar
mesh_terms: D000293:Adolescent; D001284:Atrophy; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008297:Male; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000534:rehabilitation / Q000601:surgery*; D011184:Postoperative Period; D011300:Preoperative Care; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013906:Thoracoscopy / Q000379:methods*; D013934:Thymectomy / Q000379:methods*; D013950:Thymus Gland / Q000473:pathology / Q000601:surgery; D014743:Videotape Recording