title: A streamlined synthesis for 2,3-dihydroxyterephthalamides.
abstract: [reaction: see text]. 2,3-Dihydroxyterephthalamides have been synthesized through a route that avoids the protection and deprotection of the phenol groups. The procedure allows for symmetric and unsymmetric amide linkages. This synthetic sequence significantly decreases the time and cost of preparation and increases the overall yield of this class of metal chelators.
authors.affiliation: Chemical Sciences Division, Lawrence Berkeley National Laboratory and Department of Chemistry, University of California, Berkeley, 94720, USA.
authors.forename: C J
authors.initials: CJ
authors.lastname: Gramer
authors.forename: K N
authors.initials: KN
authors.lastname: Raymond
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002614:Chelating Agents / Q000138:chemical synthesis* / Q000737:chemistry; D019800:Phenol / Q000737:chemistry; D010795:Phthalic Acids / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C435763:2,3-dihydroxyterephthalamide; D000577:Amides; D002614:Chelating Agents; D010795:Phthalic Acids; D019800:Phenol