title: Cutaneous mastocytosis associated with a mixed germ cell tumour of the ovary: report of a case and review of the literature.
abstract: A 10-year-old girl with a mixed germ cell tumour of the ovary, treated by surgery and chemotherapy, developed cutaneous mastocytosis approximately 8 months after starting chemotherapy. This is the sixth report of a germ cell tumour associated with mastocytosis. c-kit receptor point mutations, including Asp816Val and Val560Gly were absent in a biopsy specimen obtained from lesional skin.
authors.affiliation: Department of Dermatology, Nara Medical University, Kashihara City, Nara 634-8522, Japan. sachikom@naramed-u.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Miyagawa
authors.forename: S
authors.initials: S
authors.lastname: Hirota
authors.forename: Y D
authors.initials: YD
authors.lastname: Park
authors.forename: M
authors.initials: M
authors.lastname: Yamasaki
authors.forename: N
authors.initials: N
authors.lastname: Daikoku
authors.forename: H
authors.initials: H
authors.lastname: Morikawa
authors.forename: A
authors.initials: A
authors.lastname: Yoshioka
authors.forename: Y
authors.initials: Y
authors.lastname: Kitamura
authors.forename: K
authors.initials: K
authors.lastname: Ichijima
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D005260:Female; D018237:Germinoma / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008415:Mastocytosis / Q000150:complications*; D010051:Ovarian Neoplasms / Q000150:complications* / Q000188:drug therapy; D017354:Point Mutation / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics
chemical_list: D019009:Proto-Oncogene Proteins c-kit