title: Dehalogenation of chlorinated hydroxybiphenyls by fungal laccase.
abstract: We have investigated the transformation of chlorinated hydroxybiphenyls by laccase produced by Pycnoporus cinnabarinus. The compounds used were transformed to sparingly water-soluble colored precipitates which were identified by gas chromatography-mass spectrometry as oligomerization products of the chlorinated hydroxybiphenyls. During oligomerization of 2-hydroxy-5-chlorobiphenyl and 3-chloro-4-hydroxybiphenyl, dechlorinated C---C-linked dimers were formed, demonstrating the dehalogenation ability of laccase. In addition to these nonhalogenated dimers, both monohalogenated and dihalogenated dimers were identified.
authors.affiliation: Institute of Microbiology and Molecular Biology, Ernst Moritz Arndt University of Greifswald, D-17487 Greifswald, Germany. asgard.schultz@web.de
authors.forename: A
authors.initials: A
authors.lastname: Schultz
authors.forename: U
authors.initials: U
authors.lastname: Jonas
authors.forename: E
authors.initials: E
authors.lastname: Hammer
authors.forename: F
authors.initials: F
authors.lastname: Schauer
mesh_terms: D001487:Basidiomycota / Q000201:enzymology* / Q000254:growth & development; D001673:Biodegradation, Environmental; D001713:Biphenyl Compounds / Q000737:chemistry / Q000378:metabolism*; D008401:Gas Chromatography-Mass Spectrometry; D042845:Laccase; D009682:Magnetic Resonance Spectroscopy; D010088:Oxidoreductases / Q000378:metabolism*; D011078:Polychlorinated Biphenyls / Q000737:chemistry / Q000378:metabolism*
chemical_list: D001713:Biphenyl Compounds; D011078:Polychlorinated Biphenyls; D010088:Oxidoreductases; D042845:Laccase