[Crohn's disease and small intestine adenocarcinoma].
BACKGROUND
The relationship between digestive neoplasia and Crohn's disease remains debated but several cases of carcinoma have been reported in the past 10 years.


METHODS
We report two cases of intestinal adenocarcinoma found in young people. Patients were asymptomatic during 15 years after the diagnosis of inflammatory bowel disease and presented a sudden occlusive syndrome. Carcinoma was observed incidentally at gross examination, and histopathological study showed dysplasia adjacent to neoplasia. Despite adequate surgical resection, death occurred quickly.


CONCLUSIONS
Crohn's carcinoma should be suspected in patients with long-standing disease, poor symptomatology, and stenosis. Intestinoscopy surveillance remains illusory because inflammatory stenosis is often present and infiltrative neoplasia is invisible. Thus, it is important to be vigilant in this clinical presentation.
Piercecchi-Marti
M D
MD
Service d'anatomie et cytologie pathologiques, hôpital Sainte-Marguerite avenue de Sainte-Marguerite, 13009 Marseille, France. mpiercecchi@ap-hm.fr
Desjeux
A
A
Liprandi
A
A
Farisse
J
J
Sastre
B
B
Payan
M J
MJ
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D000328:Adult; D003424:Crohn Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D007414:Intestinal Neoplasms / Q000209:etiology* / Q000473:pathology; D007415:Intestinal Obstruction / Q000209:etiology / Q000473:pathology; D008297:Male
Maladie de Crohn et adénocarcinome du grêle.