Axoglial junctions: separate the channels or scramble the message.
Axoglial junctions flank the nodes of Ranvier in myelinated nerves. These large cell adhesion complexes have an essential role in sequestering potassium channels located under the myelin sheath from nodal sodium channels. Recent studies have shed new light on the composition and function of axoglial junctions.
Brophy
P J
PJ
Department of Preclinical Veterinary Sciences, University of Edinburgh, EH9 1QH, Edinburgh, UK. Peter.Brophy@ed.ac.uk
D000818:Animals; D001369:Axons / Q000502:physiology*; D007365:Intercellular Junctions / Q000502:physiology*; D008959:Models, Neurological; D009186:Myelin Sheath / Q000502:physiology; D009457:Neuroglia / Q000502:physiology*; D015221:Potassium Channels / Q000502:physiology; D011901:Ranvier's Nodes / Q000502:physiology; D015222:Sodium Channels / Q000502:physiology
D015221:Potassium Channels; D015222:Sodium Channels