title: A novel modified pterin from a Eudistoma species ascidian.
abstract: The MeOH extract of an Indonesia Eudistoma sp. ascidian contained 1,3,O(7)-trimethylisoxanthopterin (1), a novel pteridine. The purification of 1 was achieved through flash C(18) chromatography and cyano HPLC. The structure was determined primarily through the use of (1)H-(13)C and (1)H-(15)N HMBC measurements and comparison with data obtained for 1,3,7-trimethylguanine (2).
authors.affiliation: Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Van Wagoner
authors.forename: J
authors.initials: J
authors.lastname: Jompa
authors.forename: A
authors.initials: A
authors.lastname: Tahir
authors.forename: C M
authors.initials: CM
authors.lastname: Ireland
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D008401:Gas Chromatography-Mass Spectrometry; D006147:Guanine / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007214:Indonesia; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011622:Pterins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D014561:Urochordata / Q000737:chemistry*
chemical_list: C436784:1,3,7-trimethylguanine; C436785:1,3,O(7)-trimethylisoxanthopterin; D011622:Pterins; D006147:Guanine