Cardiovascular effects of the methanol and dichloromethanol extracts from Mentha suaveolens Ehrh.
Methanol and dichloromethanol extracts of the leaves and stems of Mentha suaveolens Ehrh. have been tested for their effects on resting arterial blood pressure, heart rate and noradrenaline induced hypertension. Both extracts administered by i.v. bolus to urethane anaesthetized normotensive rats reduced the mean arterial blood pressure and heart rate, while only the dichloromethanol extract prevented the noradrenaline induced hypertension.
Bello
R
R
Departmento de Farmacología, Facultad de Medicina y Odontología, Universidad de Valencia, Avda. Blasco Ibarez 15, 46010 Valencia, Spain.
Calatayud
S
S
Beltrán
B
B
Primo-Yúfera
E
E
Esplugues
J
J
D000818:Animals; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006973:Hypertension / Q000139:chemically induced / Q000517:prevention & control*; D007262:Infusions, Intravenous; D019686:Lamiaceae; D009638:Norepinephrine; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D018515:Plant Leaves; D018547:Plant Stems; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
D000959:Antihypertensive Agents; D010936:Plant Extracts; D009638:Norepinephrine