title: Thymol derivatives from Eupatorium fortunei.
abstract: Sixteen new thymol derivatives have been isolated from Eupatorium fortunei and their structures determined based on spectroscopic data. They were classified into three groups (i-iii) depending on the oxidation levels: (i) one oxygen function at the 9-position, (ii) two oxygen functions at the 8- and 9-positions, and (iii) three oxygen functions at the 8-, 9-, and 10-positions. The hydroxyl groups are acylated with tigloyl, angeloyl, acetyl, isobutyryl, 3-methyl-2-butenoyl, or 2-methylbutyryl moieties. The compounds having chiral centers showed no specific rotation and exist as racemic mixtures.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. tori@ph.bunri-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Tori
authors.forename: Y
authors.initials: Y
authors.lastname: Ohara
authors.forename: K
authors.initials: K
authors.lastname: Nakashima
authors.forename: M
authors.initials: M
authors.lastname: Sono
mesh_terms: D002851:Chromatography, High Pressure Liquid; D007564:Japan; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013943:Thymol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D013943:Thymol