title: Arterial compliance is an independent factor predicting acute hemodynamic performance of intra-aortic balloon counterpulsation.
abstract: Data concerning the effect of arterial compliance (AC) on hemodynamics during intraaortic balloon counterpulsation (IABC) are lacking. This study examines the effect of AC on acute hemodynamics induced by IABC in 15 patients with post-infarction cardiogenic shock. AC was estimated by aortic pulse wave analysis using the reflection time index (RTI). Measurements were obtained once per day during IABC. The % reduction in systolic aortic pressure (ASAP), end-diastolic aortic pressure (AEDAP) and the peak aortic diastolic augmentation (PADA) were used as performance indices of IABC; 107 sets of measurements were obtained. Multivariate analysis indicated an independent association of each IABC performance index with AC (p<0.05). A high AC group (RTI< or =20.6%, n=40) and a low AC group (RTI>20.6%, n=67) were obtained. DeltaSAP deltaEDAP and PADA were significantly higher in the low AC group by almost 75%, 54.6% and 11.3% (p<0.03), while arterial blood pressure did not significantly differ. Arterial compliance is an independent factor affecting hemodynamics during IABC. RTI values higher than 20.6% may predict a better acute hemodynamic response to IABC.
authors.affiliation: Department of Clinical Therapeutics, Alexandra Hospital, Medical School, Athens University, Greece. theopap@central.ntua.gr
authors.forename: T G
authors.initials: TG
authors.lastname: Papaioannou
authors.forename: J P
authors.initials: JP
authors.lastname: Lekakis
authors.forename: A G
authors.initials: AG
authors.lastname: Dagre
authors.forename: K S
authors.initials: KS
authors.lastname: Stamatelopoulos
authors.forename: J
authors.initials: J
authors.lastname: Terrovitis
authors.forename: E J
authors.initials: EJ
authors.lastname: Gialafos
authors.forename: J
authors.initials: J
authors.lastname: Kanakakis
authors.forename: J
authors.initials: J
authors.lastname: Nanas
authors.forename: S F
authors.initials: SF
authors.lastname: Stamatelopoulos
authors.forename: S
authors.initials: S
authors.lastname: Moulopoulos
mesh_terms: D000368:Aged; D001011:Aorta / Q000502:physiology*; D001013:Aorta, Thoracic / Q000502:physiology; D003187:Compliance; D005260:Female; D005263:Femoral Artery / Q000502:physiology; D006439:Hemodynamics; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests