title: Quantitative analysis of normal major salivary glands using computed tomography.
abstract: OBJECTIVE
  We sought to calculate the size and the computed tomography (CT) number of normal parotid and submandibular glands and to evaluate their relationship with respect to sex, age, and obesity in the Korean population.
  
  
  METHODS
  The authors investigated the axial CT images of 42 healthy volunteers. The maximum cross-sectional area (MCSA) was used as an indicator of the size of the gland. Three regions of interest on axial scans were selected to calculate the mean CT number.
  
  
  RESULTS
  There was a significant decrease in the mean MCSA of the submandibular gland and the CT number of both glands with age. The MCSA of the submandibular gland in males was larger than that in females. There was a close correlation between the parotid and the submandibular glands with respect to the CT number, as well as between the left and right glands with respect to the MCSA and the CT number. The body mass index was positively correlated with the MCSA of the parotid gland, whereas the body mass indexes and the CT numbers of both glands were negatively correlated.
  
  
  CONCLUSIONS
  Both age and obesity are closely correlated with the size and the CT number of the major salivary glands. Moreover, the correlation between the CT numbers of the parotid and the submandibular glands may be used for diagnostic purposes.
authors.affiliation: Department of Oral and Maxillofacial Radiology and Dental Research Institute, College of Dentistry, Seoul National University, Korea.
authors.forename: M S
authors.initials: MS
authors.lastname: Heo
authors.forename: S C
authors.initials: SC
authors.lastname: Lee
authors.forename: S S
authors.initials: SS
authors.lastname: Lee
authors.forename: H M
authors.initials: HM
authors.lastname: Choi
authors.forename: S C
authors.initials: SC
authors.lastname: Choi
authors.forename: T W
authors.initials: TW
authors.lastname: Park
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D019412:Anatomy, Cross-Sectional; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000000981:diagnostic imaging; D010306:Parotid Gland / Q000000981:diagnostic imaging*; D012044:Regression Analysis; D012737:Sex Factors; D018709:Statistics, Nonparametric; D013363:Submandibular Gland / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed