Rate of Staphylococcus aureus nasal carriage in immunocompromised patients receiving haemodialysis treatment.
Specimens from the nose and throat were collected from 28 long-term haemodialysed patients. Staphylococcus aureus strains were isolated from sixteen patients who been on haemodialysis for over 113 months. Cytokine levels, as well as full blood cell differential counts and cell surface antigens were determined in these patients. The serum concentration of TGF-beta was significantly higher in patients carrying Staphylococcus aureus. CD14 and HLA-DR molecule expression on monocytes, as well as NK cell percentage was significantly different in S. aureus carriers. Our preliminary results suggest that immune status imbalance in haemodialysed patients could be related to the high incidence of S. aureus nasal carriage and infections.
Kozioł-Montewka
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Microbiology Department, University Medical School, 20-123, Lublin, Poland. koziolm@yahoo.com
Chudnicka
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Ksiazek
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Majdan
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D000328:Adult; D002353:Carrier State / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology*; D016207:Cytokines / Q000097:blood; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009666:Nose / Q000382:microbiology*; D010614:Pharynx / Q000382:microbiology; D006435:Renal Dialysis; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*
D016207:Cytokines