title: (-)-Terpestacin and L-tenuazonic acid, inducers of pigment and aerial mycelium formation by Fusarium culmorum JP 15.
abstract: Surface cultures of Fusarium culmorum JP15 were found to respond to extracts of other fungi by enhanced production of orange-red fusarubin pigments and formation of aerial mycelium. Two inducers from strain Ulocladium sp. HKI 0226, the new (-)-terpestacin (1) and L-tenuazonic acid (2), were isolated. 1 inhibited syncytium formation by cells infected with respiratory syncytial virus (RSV).
authors.affiliation: Department of Biostructure Chemistry, Hans-Knöll-Institute for Natural Products Research, Beutenbergstrasse 11, D-07745 Jena, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Schlegel
authors.forename: M
authors.initials: M
authors.lastname: Schmidtke
authors.forename: H
authors.initials: H
authors.lastname: Dörfelt
authors.forename: P
authors.initials: P
authors.lastname: Kleinwächter
authors.forename: U
authors.initials: U
authors.lastname: Gräfe
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000378:metabolism*; D003470:Culture Media; D005670:Fusarium / Q000254:growth & development*; D013058:Mass Spectrometry / Q000379:methods; D009024:Morphogenesis; D010860:Pigments, Biological / Q000096:biosynthesis*; D012136:Respiratory Syncytial Viruses / Q000502:physiology; D013720:Tenuazonic Acid / Q000378:metabolism*
chemical_list: D001643:Bridged Bicyclo Compounds; D003470:Culture Media; D010860:Pigments, Biological; C080890:terpestacin; D013720:Tenuazonic Acid