title: Comparison of quality of life and nutritional parameters after total gastrectomy and a new type of pouch construction with simple Roux-en-Y reconstruction: preliminary results of a prospective, randomized, controlled study.
abstract: The aim of the study was to introduce a new type of gastric substitute, the aboral pouch, after total gastrectomy and to compare nutritional, motility, and quality of life parameters of patients with an aboral pouch to those undergoing simple Roux-en-Y reconstruction in a prospective, randomized, and controlled trial. To date 40 patients have entered the study. In 22 of them the aboral pouch was created; the remaining 18 patients with simple Roux-en-Y reconstruction served as the control group. Laboratory measurements, passage studies, lipid and carbohydrate absorption tests, and quality of life interviews were carried out as follow-up examinations. Preliminary results suggest that the aboral pouch has some advantages over simple Roux-en-Y reconstruction. Serum immunoglobulin M level and the quality of life estimated by the gastrointestinal quality of life index, yielded significantly better results in the pouch group.
authors.affiliation: First Department of Surgery, University Medical School of Pécs, Hungary.
authors.forename: K
authors.initials: K
authors.lastname: Kalmár
authors.forename: L
authors.initials: L
authors.lastname: Cseke
authors.forename: K
authors.initials: K
authors.lastname: Zámbó
authors.forename: O P
authors.initials: OP
authors.lastname: Horváth
mesh_terms: D000368:Aged; D000713:Anastomosis, Roux-en-Y; D004947:Esophagus / Q000601:surgery; D005260:Female; D005743:Gastrectomy; D005769:Gastrointestinal Motility; D006801:Humans; D007408:Intestinal Absorption; D007583:Jejunum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D011446:Prospective Studies; D011788:Quality of Life; D013270:Stomach / Q000601:surgery; D013274:Stomach Neoplasms / Q000601:surgery*