title: [Current concepts in therapy of reflux disease].
abstract: Proton pump inhibitors have replaced H2-blockers as first line agents for the therapy of gastroesophageal reflux disease due to their effective acid suppression and faster healing rate. The endoscopic severity of esophagitis and the clinical response are the most important determinants of dosing and duration of therapy. In patients with severe esophagitis continuous maintenance treatment with proton pump inhibitors is recommended. In recent years antireflux surgery has been established as an important alternative therapy.
authors.affiliation: I. Internen Abteilung mit Schwerpunkt Gastroenterologie des A. ö. Krankenhauses der Barmherzigen Schwestern vom Heiligen Kreuz, Wels. andreas.kirchgatterer@khwels.at
authors.forename: A
authors.initials: A
authors.lastname: Kirchgatterer
authors.forename: G
authors.initials: G
authors.lastname: Aschl
authors.forename: M
authors.initials: M
authors.lastname: Hinterreiter
authors.forename: B
authors.initials: B
authors.lastname: Stadler
authors.forename: P
authors.initials: P
authors.lastname: Knoflach
mesh_terms: D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004942:Esophagitis, Peptic / Q000175:diagnosis / Q000188:drug therapy*; D004945:Esophagoscopy; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D054328:Proton Pump Inhibitors; D016896:Treatment Outcome
chemical_list: D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors
vernacular_title: Aktuelle Konzepte in der Therapie der Refluxerkrankung.