title: Concurrent herpes simplex type 1 and varicella-zoster in the V2 dermatome in an immunocompetent patient.
abstract: A unique feature of herpesviruses is their ability to establish latent infection within the nervous system by colonizing peripheral sensory ganglia, which results in subsequent episodic outbreaks of infection triggered by precipitating events. Despite the latent nature of both herpes simplex virus type 1 (HSV-1) and varicella-zoster virus (VZV) within these sensory ganglia, simultaneous outbreaks of these viruses are uncommon. This is generally attributed to the differing reactivation features of these 2 viruses. Four cases of concurrent HSV-1 and VZV infection are described in the literature. We report concurrent infection of HSV-1 and VZV within the same V2 dermatome in an immunocompetent patient.
authors.affiliation: Department of Medicine, Columbia University College of Physicians & Surgeons, New York, New York, USA.
authors.forename: C
authors.initials: C
authors.lastname: De Vivo
authors.forename: M G
authors.initials: MG
authors.lastname: Bansal
authors.forename: M
authors.initials: M
authors.lastname: Olarte
authors.forename: M E
authors.initials: ME
authors.lastname: Grossman
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage; D000368:Aged; D000369:Aged, 80 and over; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D006562:Herpes Zoster / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D018259:Herpesvirus 1, Human / Q000302:isolation & purification*; D014645:Herpesvirus 3, Human / Q000302:isolation & purification*; D006801:Humans; D007121:Immunocompetence; D007275:Injections, Intravenous; D008297:Male
chemical_list: D000212:Acyclovir