Opioid overdose in a patient using a fentanyl patch during treatment with a warming blanket.
This case describes the narcotic overdose associated with the use of a fentanyl transdermal patch in a patient being rewarmed with an external warming blanket during surgery. The clinical manifestation and the presumed pharmacokinetic mechanism responsible for the fentanyl overdose are discussed.
Frölich
M A
MA
Department of Anesthesiology, University of Florida Colleges of Medicine and Veterinary Medicine, Gainesville, Florida, USA. froelich@anest.ufl.edu
Giannotti
A
A
Modell
J H
JH
Frölich
M
M
D000279:Administration, Cutaneous; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D062787:Drug Overdose / Q000628:therapy*; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D017694:Rewarming / Q000009:adverse effects*; D013978:Tibial Fractures / Q000601:surgery
D000701:Analgesics, Opioid; D005283:Fentanyl