Primary central nervous system T-cell lymphoma.
Most primary CNS lymphomas (PCNSL) are B-cell neoplasms; T-cell lymphomas are quite rare. The authors report two young patients with T-cell PCNSL who had a complete response to chemo- and radiotherapy but developed recurrent disease and died 11 and 13 months from diagnosis. The prognosis of T-cell PCNSL may be worse than that of comparable B-cell tumors.
Gijtenbeek
J M
JM
Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Rosenblum
M K
MK
DeAngelis
L M
LM
D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D003561:Cytarabine / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D011379:Prognosis
D000964:Antimetabolites, Antineoplastic; D003561:Cytarabine; D008727:Methotrexate