Genotype transposer: automated genotype manipulation for linkage disequilibrium analysis.
The purpose of this work is to provide the modern molecular geneticist with tools to perform more efficient and more accurate analysis of the genotype data they produce. By using Microsoft Excel macros written in Visual Basic, we can translate genotype data into a form readable by the versatile software 'Arlequin', read the Arlequin output, calculate statistics of linkage disequilibrium, and put the results in a format for viewing with the software 'GOLD'.


BACKGROUND
The software is available by FTP at: ftp://xcsg.iarc.fr/cox/Genotype_Transposer/.


BACKGROUND
Detailed instruction and examples are available at: ftp://xcsg.iarc.fr/cox/Genotype&_Transposer/. Arlequin is available at: http://lgb.unige.ch/arlequin/. GOLD is available at: http://www.well.ox.ac.uk/asthma/GOLD/.
Cox
D G
DG
Genome Analysis Group, International Agency for Research on Cancer, 69008 Lyon, France. cox@iarc.fr
Canzian
F
F
D019295:Computational Biology; D005826:Genetics, Medical; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D015810:Linkage Disequilibrium; D020641:Polymorphism, Single Nucleotide; D012984:Software; D012985:Software Design