title: Adenomatoid hyperplasia of the palate mimicking clinically as a salivary gland tumor.
abstract: This report describes an illustrative case of adenomatoid hyperplasia (AH) of the minor salivary glands on the palate of a 31-year-old man. The clinical features of the present lesion corresponded with those of pleomorphic adenoma, but histologically large lobules of normal-appearing mucous acini were found. The cell proliferative activity demonstrated in histological sections, by an immunohistochemical staining of proliferating cell nuclear antigen and Ki-67, showed no statistically significant differences among AH and a matched control group of normal palatal salivary glands. This case suggests that AH apparently exhibits an idiopathic, focal hypertrophic lesion of intraoral mucous glands with limited growth potential.
authors.affiliation: Department of Oral Surgery, Saitama Medical Center, Saitama Medical School, Kawagoe, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Shimoyama
authors.forename: M
authors.initials: M
authors.lastname: Wakabayashi
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: T
authors.initials: T
authors.lastname: Kaneko
authors.forename: N
authors.initials: N
authors.lastname: Horie
authors.forename: F
authors.initials: F
authors.lastname: Ide
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000328:Adult; D016022:Case-Control Studies; D002455:Cell Division; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D006965:Hyperplasia; D006984:Hypertrophy; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000032:analysis; D008297:Male; D009093:Mucus; D010159:Palate / Q000473:pathology*; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000473:pathology*; D013223:Statistics as Topic
chemical_list: D019394:Ki-67 Antigen; D018809:Proliferating Cell Nuclear Antigen