title: Abp1p and cortactin, new "hand-holds" for actin.
abstract: Recently, two new ligands of the Arp2/3 complex have been described that may shed light on the way cells organize complex networks of actin in response to signals. Abp1p, a yeast protein involved in endocytosis, and cortactin, a mammalian src substrate, both enhance the ability of the Arp2/3 complex to assemble branched actin filament networks.
authors.affiliation: School of Biosciences, Division of Molecular Cell Biology, University of Birmingham, Birmingham B15 2TT, United Kingdom.
authors.forename: I M
authors.initials: IM
authors.lastname: Olazabal
authors.forename: L M
authors.initials: LM
authors.lastname: Machesky
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism*; D051377:Actin-Related Protein 2; D051378:Actin-Related Protein 3; D000199:Actins / Q000378:metabolism*; D003598:Cytoskeletal Proteins; D004705:Endocytosis; D005656:Fungal Proteins / Q000378:metabolism*; D008840:Microfilament Proteins / Q000378:metabolism*; D008954:Models, Biological; D011485:Protein Binding; D029701:Saccharomyces cerevisiae Proteins; D015398:Signal Transduction
chemical_list: C062612:ABP1 protein, S cerevisiae; D051377:Actin-Related Protein 2; D051378:Actin-Related Protein 3; D000199:Actins; D003598:Cytoskeletal Proteins; D005656:Fungal Proteins; D008840:Microfilament Proteins; D029701:Saccharomyces cerevisiae Proteins