title: [Rheumatic disease and depression].
abstract: We reviewed depressive symptoms in rheumatic disease. In systemic lupus erythematosus(SLE), depressive symptoms are frequently mentioned with the prevalence rate about 30% and usually respond to antidepressant. The duration of symptoms is within two months in most patients. Antibodies to ribosomal P protein appear to be a specific marker for SLE with depression. Single photon emission tomography but magnetic resonance imaging may also be useful for predicting the development of depressive symptoms. We also reported a patient of dermatomyositis with manic-depressive state who showed decreased cerebral blood flow in the left frontal and temporal regions during depressive state.
authors.affiliation: Department of Neuropsychiatry, Yamagata University School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Kawakatsu
authors.forename: T
authors.initials: T
authors.lastname: Wada
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000097:blood; D015415:Biomarkers / Q000097:blood; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D003882:Dermatomyositis / Q000150:complications*; D003952:Diagnostic Imaging; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D015995:Prevalence; D015800:Protozoan Proteins; D012269:Ribosomal Proteins / Q000276:immunology
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; C064601:L12E protein, Trypanosoma cruzi; D015800:Protozoan Proteins; D012269:Ribosomal Proteins