title: Advanced peritonitis and subclinical disseminated intravascular coagulopathy associated with Chlamydia trachomatis infection.
abstract: A 29-y-old woman was admitted to our hospital complaining of slight fullness of the lower abdomen. Ultrasound echographic study and magnetic resonance imaging showed pleural effusion and pelvic ascites. Laboratory investigation revealed anemia and thrombocytopenia (hemoglobin 6 mmol/l; platelets 7 x 10(10)/l), remarkable polyclonal hypergammopathy (gamma immunoglobulin 7.7 g/dl) and subclinical disseminated intravascular coagulopathy (DIC). By laparoscopy, extensive adhesion of the peritoneum and bilateral ovarian tubes was observed. From the appearance of adhesion, we suspected Chlamydia trachomatis infection and performed serologic and molecular studies. Administration of clarithromycin resolved hypergammopathy, DIC and ascites.
authors.affiliation: The Third Department of Internal Medicine, Gunma University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tsukada
authors.forename: S
authors.initials: S
authors.lastname: Tamura
authors.forename: H
authors.initials: H
authors.lastname: Mitsuhashi
authors.forename: K
authors.initials: K
authors.lastname: Ueki
authors.forename: A
authors.initials: A
authors.lastname: Maezawa
authors.forename: Y
authors.initials: Y
authors.lastname: Nojima
mesh_terms: D000328:Adult; D002690:Chlamydia Infections / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000382:microbiology*; D005260:Female; D006801:Humans; D010538:Peritonitis / Q000382:microbiology*; D012720:Severity of Illness Index