[Value of molecular biological methods in the diagnosis of urogenital tuberculosis].
Enzyme immunoassay (EIA) was used to study the diagnostic value of determination of serum Mycobacterium tuberculosis (MBT) antibodies in 41 patients with active urinary tract tuberculosis, 14 with inactive tuberculosis and 140 with nontuberculous diseases of the urinary system. The sensitivity of EIA was 73% with 88.6% sensitivity. Polymerase chain reaction revealed the causative agent of tuberculosis in the urine samples of 16 out of 17 patients with active urinary tract tuberculosis, negative tests were observed in 4 cured patients and 39 patients with nontuberculous diseases of the urinary tract (100% specificity).
Mukanbaev
K
K
Vladimirskiĭ
M A
MA
Shipina
L K
LK
Aleksandrov
A A
AA
D000907:Antibodies, Bacterial / Q000032:analysis*; D004269:DNA, Bacterial / Q000032:analysis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics* / Q000276:immunology*; D016133:Polymerase Chain Reaction; D014401:Tuberculosis, Urogenital / Q000175:diagnosis*
D000907:Antibodies, Bacterial; D004269:DNA, Bacterial
Znachenie molekuliarno-biologicheskikh metodov v diagnostike mochepolovogo tuberkuleza.