[Levels of mucin-antigen 3EG5 in the blood and bronchoalveolar swabs in patients with tuberculosis, sarcoidosis and fibrosing alveolitis].
The levels of the antigen mucin 3EG5, a marker of the activity of interstitial lung diseases, were studied in the sera and bronchoalveolar swabs of patients with active tuberculosis, sarcoidosis of the respiratory organs, and idiopathic and exogenous allergic alveolitis. Its higher blood levels were detectable in patients with alveolitis (exogenous allergic ones to a greater extent) and absent in active tuberculosis and sarcoidosis. There was a correlation of the levels of the antigen mucin 3EG5 in the blood and bronchoalveolar swabs with the degree of lymphocytosis in the endopulmonal cytogram. The fact that there is a high variability of the blood levels of the antigen mucin 3EG5 in the range of nosological entities calls the differential diagnostic informative value of this parameter to question.
Stepanian
I E
IE
Lebedin
Iu S
IuS
Filippov
V P
VP
Kuklina
G M
GM
Chuchalin
A G
AG
Shmelev
E I
EI
D000328:Adult; D000368:Aged; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis / Q000276:immunology*; D000941:Antigens / Q000032:analysis* / Q000097:blood; D015415:Biomarkers; D001980:Bronchi / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000276:immunology*; D011650:Pulmonary Alveoli / Q000276:immunology; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000276:immunology*; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis / Q000276:immunology*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000276:immunology*
D000941:Antigens; D015415:Biomarkers; D009077:Mucins
Soderzhanie mutsin-antigena 3EG5 v krovi i bronkhoal'veoliarnykh smyvakh u bol'nykh tuberkulezom, sarkoidozom i firbroziruiushchimi al'veolitami.