Industrial purification of pharmaceutical antibodies: development, operation, and validation of chromatography processes.
Fahrner
R L
RL
Department of Recovery Sciences, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA. fahrner.robert@gene.com
Knudsen
H L
HL
Basey
C D
CD
Galan
W
W
Feuerhelm
D
D
Vanderlaan
M
M
Blank
G S
GS
D000911:Antibodies, Monoclonal / Q000235:genetics* / Q000302:isolation & purification / Q000627:therapeutic use; D002852:Chromatography, Ion Exchange / Q000379:methods; D005818:Genetic Engineering / Q000379:methods; D006801:Humans; D007700:Kinetics; D011994:Recombinant Proteins / Q000235:genetics / Q000302:isolation & purification / Q000627:therapeutic use; D015203:Reproducibility of Results
D000911:Antibodies, Monoclonal; D011994:Recombinant Proteins