High serum interleukin-10 and tumor necrosis factor alpha levels in chronic paracoccidioidomycosis.
In patients with chronic paracoccidioidomycosis (n = 10), levels of tumor necrosis factor alpha, interleukin-10, and interleukin-2 in serum, measured by enzyme-linked immunosorbent assay (in picograms per milliliter, as mean +/- standard error of the mean), were higher than in normal controls (n = 8): 186 +/- 40 versus 40 +/- 7 (P < 0.05), 203 +/- 95 versus 20 +/- 8 (P = 0.001), and 96.3 +/- 78.57 versus 1.19 +/- 1.19 (P = 0.045), respectively. Gamma interferon and interleukin-4 levels were similar in patients and controls.
Fornari
M C
MC
Laboratorio de Inmunofarmacologia, Facultad de Medicina (UBA), Paraguay 2155, Piso 16, 1121 Buenos Aires, Argentina.
Bava
A J
AJ
Guereño
M T
MT
Berardi
V E
VE
Silaf
M R
MR
Negroni
R
R
Diez
R A
RA
D000328:Adult; D000368:Aged; D000818:Animals; D002908:Chronic Disease; D005260:Female; D006801:Humans; D016753:Interleukin-10 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010229:Paracoccidioidomycosis / Q000097:blood / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10