title: A case of solitary fibrous tumor of the meninges.
abstract: We report a rare case of solitary fibrous tumor (SFT) of the meninges of the posterior fossa presenting as an intracerebellar hemorrhage. A 29-year-old woman was admitted with sudden-onset severe headache, nausea, and vomiting. A computed tomographic (CT) scan of the brain revealed an intracerebellar hemorrhage 3.5cm in diameter. Gadolinium-enhanced magnetic resonance imaging (MRI) showed a heterogeneous enhancement mass. A posterior craniotomy found a firm, highly vascular tumor attached to the meninges. Histologically, the tumor showed mostly sclerotic tissues with spindle cells. In few areas, the tumor had a more compact arrangement of spindle-shaped cells with vascular spaces and highly cellular components. Immunohistochemical study revealed strong CD-34 immunopositivity in many tumor cells. The tumor was diagnosed as SFT of the meninges. We report the clinical and histological features of this newly described tumor with a heterogeneous component.
authors.affiliation: Department of Neurosurgery, Tama Nagayama Hospital, Nippon Medical School, Tokyo, Japan. sanno_naoko/neurosurg@nms.ac.jp
authors.forename: N
authors.initials: N
authors.lastname: Sanno
authors.forename: T
authors.initials: T
authors.lastname: Shimura
authors.forename: S
authors.initials: S
authors.lastname: Maeda
authors.forename: A
authors.initials: A
authors.lastname: Teramoto
mesh_terms: D000328:Adult; D002526:Cerebellar Diseases / Q000209:etiology; D003388:Cranial Fossa, Posterior; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology*; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007150:Immunohistochemistry; D008577:Meningeal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology*; D014057:Tomography, X-Ray Computed