title: Murine natural killer cell activation receptors.
abstract: Natural killer (NK) cells express two types of receptors involved in target recognition: inhibitory receptors for target cell MHC class I molecules and activation receptors. While there has been significant progress in understanding the inhibitory receptors, less is known about the activation receptors. Detailed analysis of several mouse NK-cell activation receptors provides insight into the physiologic relevance of these receptors in the innate immune response.
authors.affiliation: Howard Hughes Medical Institute, Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors.forename: H R
authors.initials: HR
authors.lastname: Smith
authors.forename: A H
authors.initials: AH
authors.lastname: Idris
authors.forename: W M
authors.initials: WM
authors.lastname: Yokoyama
mesh_terms: D000818:Animals; D000950:Antigens, Ly; D015870:Gene Expression; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D037181:Lectins, C-Type; D008562:Membrane Glycoproteins / Q000235:genetics / Q000378:metabolism; D051379:Mice; D011971:Receptors, Immunologic / Q000235:genetics / Q000378:metabolism*; D055630:Receptors, NK Cell Lectin-Like; D013045:Species Specificity
chemical_list: D000950:Antigens, Ly; D037181:Lectins, C-Type; D008562:Membrane Glycoproteins; D011971:Receptors, Immunologic; D055630:Receptors, NK Cell Lectin-Like