title: [Change of bioelectric brain activity registered at the distance from the focus of cerebral tissue injury].
abstract: The focal delta-waves and the remote influences of the stroke in the form of the sinusoidal flashes of delta-waves with a maximal amplitude exceeding an amplitude of the focal delta-waves (frontal flashes--FF) in frontal-polar leads were investigated in 51 patients (22 men, 29 women) by means of mapping, dipole location (BrainLoc) and LORETA methods. The patients were examined in dynamics during the acute period of hemispheric stroke on days 1-3, 14 and 21 after the onset of the disease. The usage of the modern computer methods of EEG analysis permits to consider FF as an independent electrophysiological phenomenon and to localize a zone of the sources of such flashes, which does not coincide with the zone of generation of the focal delta-activity that corresponds to the perifocal zone of the stroke. According to the data of the three-dimensional location a probable zone of FF generation corresponds to the frontal pole and medial-basal areas of the frontal lobe. Comparison with the MRI data leads to the conclusion that a damage of anterior white substance was the most frequent cause of FF development, probably by deafferentation mechanism. FF may be an electrophysiological manifestation of the influence of the damage of the different brain structures on the frontal lobes according to diaschisis mechanism.
authors.forename: G P
authors.initials: GP
authors.lastname: Pirlik
authors.forename: V V
authors.initials: VV
authors.lastname: Gnezditskiĭ
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Koptelov
authors.forename: M K
authors.initials: MK
authors.lastname: Bodykhov
authors.forename: V I
authors.initials: VI
authors.lastname: Skvortsova
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000473:pathology / Q000503:physiopathology*; D003700:Delta Rhythm; D004569:Electroencephalography; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000175:diagnosis / Q000503:physiopathology*
vernacular_title: Izmeneniia bioélektricheskoĭ aktivnosti mozga, registriruemye na rasstoianii ot ochaga porazheniia tserebral'noĭ tkani.