title: Pulmonary reactions during treatment with amphotericin B: review of published cases and guidelines for management.
abstract: Acute respiratory events occasionally have been observed during the infusion of amphotericin B. Herein we analyze the 21 cases that have been reported, including a fatal reaction observed by us. Some useful guidelines are provided that likely will allow treatment to be continued safely for patients who have experienced such reactions.
authors.affiliation: Section of Infectious Diseases, Hospital de Galdakao, Vizcaya, Spain. jcollazos@hgda.osakidetza.net
authors.forename: J
authors.initials: J
authors.lastname: Collazos
authors.forename: E
authors.initials: E
authors.lastname: Martínez
authors.forename: J
authors.initials: J
authors.lastname: Mayo
authors.forename: S
authors.initials: S
authors.lastname: Ibarra
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage / Q000009:adverse effects*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced*; D008297:Male; D009181:Mycoses / Q000188:drug therapy*; D010713:Phosphatidylcholines / Q000008:administration & dosage / Q000009:adverse effects*; D010715:Phosphatidylglycerols / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000935:Antifungal Agents; D004338:Drug Combinations; D010713:Phosphatidylcholines; D010715:Phosphatidylglycerols; C068538:liposomal amphotericin B; D000666:Amphotericin B