Effect of dimethyl sulfoxide on the electron transfer reactivity of hemoglobin.
Hemoglobin, after being treated with dimethyl sulfoxide, exhibits a direct electrochemical response at a pyrolytic graphite electrode. The apparent standard potential (E degrees ') of hemoglobin is -0.119 V (vs. NHE). Meanwhile, since no electrochemical mediator is required for its direct electrochemistry, this work provides a convenient way to perform electrochemical research on this protein.
Fan
C
C
Department of Biochemistry and National Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, People's Republic of China.
Wagner
G
G
Li
G
G
D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D004566:Electrodes; D004579:Electron Transport; D006454:Hemoglobins / Q000737:chemistry*
D006454:Hemoglobins; D004121:Dimethyl Sulfoxide