title: Biomonitoring of contaminated mine tailings through age accumulation of trace metals in the bank vole (Clethrionomys glareolus).
abstract: Lead, zinc and cadmium were determined in a range of tissues from laboratory-bred bank voles (Clethrionomys glareolus) exposed to elevated levels of dietary zinc (124 micrograms g-1). The pelletised diet was derived from vegetation harvested from the surface of a revegetated tailings dam at a modern Zn-Pb mine. Exposure regimes to the contaminated diet were 16, 32, 64, 128 or 256 days. Elevated levels of dietary zinc were not reflected in the individual tissue or total body concentrations. Marginal age accumulation of lead and cadmium was evident in the liver (Pb) and kidney (Pb and Cd). Tissue residues did not attain toxicologically significant concentrations. Animals inhabiting the grassland are considered to be at low ecotoxicological risk with respect to trace metals.
authors.affiliation: School of Biological Sciences, Life Sciences Building, University of Liverpool, Liverpool, UK L69 7ZB. mjohnson@liv.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Milton
authors.forename: M
authors.initials: M
authors.lastname: Johnson
mesh_terms: D000818:Animals; D003411:Arvicolinae / Q000502:physiology*; D001681:Biological Assay; D004032:Diet; D004784:Environmental Monitoring / Q000379:methods*; D005260:Female; D008297:Male; D019216:Metals, Heavy / Q000032:analysis* / Q000493:pharmacokinetics; D008906:Mining; D010945:Plants, Edible / Q000737:chemistry; D012307:Risk Factors; D014018:Tissue Distribution
chemical_list: D019216:Metals, Heavy