Biologically motivated quantitative models and the mixture toxicity problem.
The article highlighted in this issue is "A PBPK Modeling-Based Approach to Account for Interactions in the Health Risk Assessment of Chemical Mixtures" by Sami Haddad, Martin Béliveau, Robert Tardif, and Kannan Krishnan (pp. 125-131).
Conolly
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CIIT Centers for Health Research, Center for Computational Biology and Extrapolation Modeling, 6 Davis Drive, Research Triangle Park, NC 27709, USA. rconnolly@ciit.org
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D015386:Hazardous Substances / Q000493:pharmacokinetics / Q000633:toxicity*; D006801:Humans; D008954:Models, Biological; D018570:Risk Assessment; D013045:Species Specificity; D018675:Toxicity Tests
D015386:Hazardous Substances