Ru-catalyzed cyclocarbonylation of alpha- and beta-allenic sulfonamides: synthesis of gamma- and delta-unsaturated lactams.
[reaction: see text]. The Ru-catalyzed cyclocarbonylation of alpha- or beta-allenic sulfonamides in the presence of Ru(3)(CO)(12) (1 mol %) and Et(3)N (1.5 equiv) under CO atmosphere (20 atm) in dioxane at 100 degrees C for 9 h gave heterocyclic gamma- and delta-unsaturated lactams in good yields.
Kang
S K
SK
Department of Chemistry and BK-21 School of Molecular Science, Sungkyunkwan University, Suwon 440-746, Korea. skkang@chem.skku.ac.kr
Kim
K J
KJ
Yu
C M
CM
Hwang
J W
JW
Do
Y K
YK
D002384:Catalysis; D003500:Cyclization; D012428:Ruthenium / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry*; D047090:beta-Lactams / Q000138:chemical synthesis* / Q000737:chemistry
D013449:Sulfonamides; D047090:beta-Lactams; D012428:Ruthenium