[Usage of the novel synthetic material carbilan for urinary tract reconstruction in experiment].
Carbilan was tried as a new synthetic suturing material and ureteral prosthesis in reconstruction surgery on the urinary tracts. In experiments on 24 dogs carbilan suturing threads were used for establishment of ureteral-ureteral and vesicoureteral anastomoses, suturing of the ureter, bladder or urethra. In a comparative group of 36 dogs such operations were made using chrome-plated catgut. Complications occurred in 3.8 and 17.6% of the dogs from the carbilan and catgut groups, respectively. Replacement of the part of the ureter in the middle or in the lower third 3-5 cm in length for a carbilan transplant was conducted in 8 dogs. In 6 cases of the suture leaking, the prosthesis underwent deformation and compression by commissures which formed around the flap within 3 months after the implantation. In 2 experiments the prosthesis was sealed with fibrin (a short-term implantation into the artery). This provided normal function of the prosthesis for 9-13 months. Later, the urinary tracts were also obstructed. No occlusions of the prosthesis with urinary salts or detritus were observed. Histologically, both suturing threads and ureteral prosthesis made of carbilan showed good biocompatibility. Massive commissures around the prosthesis arose because of its leaking and contact of the urine with the surrounding tissues.
Kirpatovskiĭ
V I
VI
Mudraia
I S
IS
Kudriavtsev
Iu V
IuV
Kudriavtsev
Iu P
IuP
Evsiukov
S E
SE
D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D011859:Radiography; D014570:Urologic Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*
Ispol'zovanie novogo sinteticheskogo materiala "karbilan" pri porazhenii mochevykh puteĭ (éksperimental'naia rabota).