title: Adjunctive therapies in the cath lab. Successful medical therapy of left main thrombosis: value of serial coronary angiography.
abstract: Acute coronary syndromes (ACS), including unstable angina, non-Q wave myocardial infarctions (MI) and Q-wave MIs, are usually the result of plaque rupture and subsequent thrombus formation. Commonly, patients with ACS have significant underlying coronary artery disease (CAD) demonstrable by coronary angiography and are candidates for prompt revascularization. In many cases, however, ACS are due to coronary thrombosis in the absence of obstructive CAD and therefore aggressive medical therapy may be sufficient. Coronary angiography is an invaluable resource for individualized treatment decisions. We describe a patient with thrombosis of the left main coronary artery successfully treated with aggressive and prolonged antiplatelet and anticoagulant therapy under the guidance of serial coronary angiography.
authors.affiliation: Cardiac Catheterization Laboratory and Division of Cardiology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. edeliarg@wfubmc.edu
authors.forename: E N
authors.initials: EN
authors.lastname: Deliargyris
authors.forename: G J
authors.initials: GJ
authors.lastname: Dehmer
authors.forename: P W
authors.initials: PW
authors.lastname: Willis
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D006493:Heparin