title: [Sarcoidosis and comorbidity: retrospective study of 32 cases].
abstract: OBJECTIVE
  A retrospective study was set up to investigate active pathologic processes associated with sarcoidosis diagnosed in 32 patients.
  
  
  METHODS
  Eighteen patients had two identified granulomatous localizations (56%) and 14 patients had three localizations or more (27%). Comorbidity was noticed in nine patients (28% of cases). Sarcoidosis was associated with an infectious disease five times (hepatitis C virus [HCV] infection three times, including one case after recombinant interferon alpha therapy, and HIV and HCV co-infection two times). The association of sarcoidosis with a chronic immunologic inflammatory disease was noticed four times (lupus erythematosus two times, myasthenia and primary biliary cirrhosis). Finally, in two cases sarcoidosis was associated with a neoplasia (non-Hodgkin's lymphoma in a co-infected HIV-HCV patient, ovarian cystadenocarcinoma in another patient). Sarcoidosis preceded or revealed the comorbidity four times.
authors.affiliation: Fédération de médecine interne, maladies infectieuses et pathologie tropicale, hôpital Saint-André, 1, rue Jean-Burguet, 33075 Bordeaux, France. fabrice.bonnet@chu-bordeaux.fr
authors.forename: F
authors.initials: F
authors.lastname: Bonnet
authors.forename: J
authors.initials: J
authors.lastname: Dubuc
authors.forename: P
authors.initials: P
authors.lastname: Morlat
authors.forename: X
authors.initials: X
authors.lastname: Delbrel
authors.forename: M S
authors.initials: MS
authors.lastname: Doutre
authors.forename: S
authors.initials: S
authors.lastname: de Witte
authors.forename: N
authors.initials: N
authors.lastname: Bernard
authors.forename: D
authors.initials: D
authors.lastname: Lacoste
authors.forename: M
authors.initials: M
authors.lastname: Longy-Boursier
authors.forename: J
authors.initials: J
authors.lastname: Beylot
mesh_terms: D000328:Adult; D000368:Aged; D015897:Comorbidity; D003536:Cystadenocarcinoma / Q000150:complications; D005260:Female; D015658:HIV Infections / Q000150:complications; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D007154:Immune System Diseases / Q000150:complications*; D008105:Liver Cirrhosis, Biliary / Q000150:complications; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications; D009369:Neoplasms / Q000150:complications*; D010051:Ovarian Neoplasms / Q000150:complications; D012107:Research Design; D012189:Retrospective Studies; D012307:Risk Factors; D012507:Sarcoidosis / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D014777:Virus Diseases / Q000150:complications*
vernacular_title: Sarcoïdose et comorbidité: étude rétrospective de 32 observations.