Mycoplasma conjunctivae infection is self-maintained in the Swiss domestic sheep population.
Bacteriological and serological investigations were performed to assess whether the domestic sheep population is a reservoir of Mycoplasma conjunctivae in Switzerland. Among a sample of 69 sheep showing clinical signs of infectious keratoconjunctivitis (IKC) in three Swiss cantons, M. conjunctivae was identified 53 times (76.8%). A commercially prepared indirect ELISA was used to detect M. conjunctivae antibodies in 674 sera of adult sheep. We analysed a stratified random sample of 123 sheep herds from 25 out of the 26 Swiss cantons. At least one positive animal was detected in 89.4% of the herds. In positive herds (n=110), 57.1% of the individual animals tested positive. To assess the importance of sheep's age in the spread of M. conjunctivae, 209 sera of adult sheep and 93 lamb sera among eight sheep herds were analysed using the indirect ELISA. Seroprevalence in 2-6-month-old lambs was 50.5%, indicating that the IKC agent is spread in sheep flocks during raising. Lambs experimentally infected with M. conjunctivae carried the agent for 8 and 23 weeks, respectively, depending on the strain used for challenge. We conclude that the M. conjunctivae-infection is endemic and self-maintained in the domestic sheep population in Switzerland.
Janovsky
M
M
Institute of Animal Pathology, University of Berne, Länggassstrasse 122, CH-3012 Berne, Switzerland.
Frey
J
J
Nicolet
J
J
Belloy
L
L
Goldschmidt-Clermont
E
E
Giacometti
M
M
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D002353:Carrier State / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D004197:Disease Reservoirs / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D007639:Keratoconjunctivitis, Infectious / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D008297:Male; D009174:Mycoplasma / Q000276:immunology; D016036:Seroepidemiologic Studies; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D013557:Switzerland / Q000453:epidemiology
D000907:Antibodies, Bacterial