title: A multicenter survey on automated peritoneal dialysis prescription in children.
abstract: Automated peritoneal dialysis (APD) is considered the first-choice chronic peritoneal dialysis modality for pediatric patients. Nighttime APD courses reduce the impact of PD treatment on a patient's and family's way of life, and the wide range of prescription options permit the dialysis schedule to be tailored to the needs of children of varying age and body size. We registered data concerning the dialytic regimens adopted in 12 pediatric dialysis centers for the treatment of 110 children on APD. Of the 110 children, 64 (aged 7.6 +/- 5.1 years) were on nightly intermittent peritoneal dialysis (NIPD); 29 (aged 9.2 +/- 4.3 years) were on tidal peritoneal dialysis (TPD); and 17 (aged 8.2 +/- 4.9 years) were on continuous cycling peritoneal dialysis (CCPD). The main prescription parameters for the various regimens (mean +/- standard deviation) were these: NIPD--exchanges: 13.0 +/- 5.8; duration: 10.0 +/- 1.1 hours; dwell volume: 36.5 +/- 6.2 mL/kg body weight (BW); glucose concentration: 1.69% +/- 0.41%. TPD--exchanges: 23.3 +/- 8.1; duration: 10.0 +/- 1.0 hours; dwell volume: 36.1 +/- 5.9 mL/kg BW; glucose concentration: 1.63% +/- 0.37%. CCPD--exchanges: 13.0 +/- 4.7; duration: 10.1 +/- 1.3 hours; dwell volume: 37.7 +/- 5.2 mL/kg BW; glucose concentration: 1.65% +/- 0.28%. Tidal volume was 52.2% +/- 9.0% of initial fill volume. Daytime dwell volume was 54.8% +/- 17.3% of night volume in CCPD patients, and 56.6% +/- 13.3% in 9 patients on continuous TPD. Because the patient population in this report varied in age, body size, and metabolic needs, the resulting range in prescription parameters was quite wide. Nevertheless, the duration of nightly PD sessions averaged 10 hours, fill volume averaged 36 mL per kilogram body weight, and daytime volume averaged 50% of nighttime fill volume.
authors.affiliation: Nephrology Division, G. Gaslini Children's Hospital, Largo G. Gaslini, 5, Genoa 16148, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Verrina
authors.forename: G
authors.initials: G
authors.lastname: Zacchello
authors.forename: A
authors.initials: A
authors.lastname: Edefonti
authors.forename: P
authors.initials: P
authors.lastname: Sorino
authors.forename: S
authors.initials: S
authors.lastname: Rinaldi
authors.forename: B
authors.initials: B
authors.lastname: Gianoglio
authors.forename: G
authors.initials: G
authors.lastname: Lavoratti
authors.forename: S
authors.initials: S
authors.lastname: Maringhini
authors.forename: F
authors.initials: F
authors.lastname: Perfumo
mesh_terms: D002648:Child; D003625:Data Collection; D015314:Dialysis Solutions; D006801:Humans; D007558:Italy; D010044:Outpatient Clinics, Hospital; D010530:Peritoneal Dialysis / Q000379:methods* / Q000706:statistics & numerical data; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000379:methods / Q000706:statistics & numerical data
chemical_list: D015314:Dialysis Solutions