Mannose-binding lectin polymorphisms in a Canary Islands (Spain) population.
We have compared the structural and promoter variants of the mannose-binding lectin (MBL) gene in a population from Gran Canaria with that from other populations previously reported. The observed frequencies of the seven alleles of the MBL gene in our population were: HYPA, 0.24; LYQA, 0.22; LYPA, 0.08; LXPA, 0.19; LYPB, 0.17; LYQC, 0.03 and HYPD, 0.07. The frequency of non-producer alleles and of MBL-deficient individuals in our population is higher than in other European and Asian population.
García-Laorden
M I
MI
Department of Immunology, Hospital de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain.
Manzanedo
A
A
Figuerola
A
A
Sánchez-García
F
F
Rodríguez-Gallego
C
C
D001266:Atlantic Islands; D002352:Carrier Proteins / Q000235:genetics*; D037222:Collectins; D005260:Female; D006801:Humans; D037102:Lectins / Q000235:genetics; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics*; D013030:Spain; D044465:White People / Q000235:genetics
D002352:Carrier Proteins; D037222:Collectins; D037102:Lectins