title: Relationships among calcaneal backscatter, attenuation, sound speed, hip bone mineral density, and age in normal adult women.
abstract: The present study was undertaken in order to investigate the use of calcaneal ultrasonic backscatter for the application of diagnosis of osteoporosis. Broadband ultrasonic attenuation (BUA), speed of sound (SOS), the average backscatter coefficient (ABC), and the hip bone mineral density (BMD) were measured in calcanea in 47 women (average age: 58 years, standard deviation: 13 years). All three ultrasound variables had comparable correlations with hip BMD (around 0.5). As reported previously by others, BUA and SOS were rather highly correlated with each other. The logarithm of the ABC was only moderately correlated with the other two. The three ultrasound parameters exhibited similar moderate negative correlations with age. These results taken collectively suggest that the ABC may carry important diagnostic information independent of that contained in BUA and SOS and, therefore, may be useful as an adjunct measurement in the diagnosis of osteoporosis.
authors.affiliation: US Food and Drug Administration, Center for Devices and Radiological Health, Rockville, Maryland 20852, USA. kaw@cdrh.fda.gov
authors.forename: K A
authors.initials: KA
authors.lastname: Wear
authors.forename: D W
authors.initials: DW
authors.lastname: Armstrong
mesh_terms: D000125:Achilles Tendon / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D015519:Bone Density / Q000502:physiology*; D002111:Calcaneus / Q000000981:diagnostic imaging*; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D012016:Reference Values; D012542:Scattering, Radiation; D014463:Ultrasonography