title: Rhinovirus RNA in the maxillary sinus epithelium of adult patients with acute sinusitis.
abstract: We used in situ hybridization for the detection of rhinovirus in maxillary sinus biopsy specimens obtained from 14 adult patients with acute sinusitis. In 7 specimens, rhinovirus RNA could be demonstrated in the maxillary sinus epithelium, thereby confirming the etiology of rhinovirus and the clinical suspicion of acute sinusitis.
authors.affiliation: Department of Otorhinolaryngology, University of Helsinki, Helsinki, Finland. anne.pitkaranta@hus.fi
authors.forename: A
authors.initials: A
authors.lastname: Pitkäranta
authors.forename: M
authors.initials: M
authors.lastname: Starck
authors.forename: S
authors.initials: S
authors.lastname: Savolainen
authors.forename: T
authors.initials: T
authors.lastname: Pöyry
authors.forename: I
authors.initials: I
authors.lastname: Suomalainen
authors.forename: T
authors.initials: T
authors.lastname: Hyypiä
authors.forename: O
authors.initials: O
authors.lastname: Carpen
authors.forename: A
authors.initials: A
authors.lastname: Vaheri
mesh_terms: D000208:Acute Disease; D000328:Adult; D004848:Epithelium / Q000821:virology; D005260:Female; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D008443:Maxillary Sinus / Q000821:virology; D015523:Maxillary Sinusitis / Q000821:virology*; D010850:Picornaviridae Infections / Q000821:virology; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification*; D012229:Rhinovirus / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D012367:RNA, Viral