A decreased serum leptin level in patients with systemic sclerosis.
Serum leptin levels were determined in 31 women with systemic sclerosis and 24 age-matched healthy controls. Both groups were divided into premenopausal and postmenopausal subgroups. A decreased serum leptin was found in the patients with systemic sclerosis. The premenopausal patients and controls had higher serum leptin than those in the postmenopausal subgroups. Serum leptin correlated with body mass index in the patients with systemic sclerosis.
Kotulska
A
A
Department of Internal Medicine and Rheumatology, Medical University of Silesia, Katowice, Poland.
Kucharz
E J
EJ
Brzezińska-Wcisło
L
L
Wadas
U
U
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D020738:Leptin / Q000032:analysis / Q000097:blood*; D008875:Middle Aged; D017698:Postmenopause; D017697:Premenopause; D011336:Probability; D011379:Prognosis; D012595:Scleroderma, Systemic / Q000097:blood* / Q000175:diagnosis; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric
D015415:Biomarkers; D020738:Leptin