Unexpected reactivity of acetylenic omega-ketoesters toward TBAF and t-BuOK; new cascade reactions affording allene and oxetane derivatives.
[reaction: see text]. The reactivity of acetylenic omega-ketoesters toward tetra-n-butylammonium fluoride and potassium tert-butoxide was studied. These cascade reactions proceeded smoothly and afforded either electrophilic allene derivatives or highly functionalized oxetane derivatives in moderate to high yields.
Wendling
F
F
Université Louis Pasteur, Institut de Chimie-LCOS, 1, rue Blaise Pascal BP 296/R8 67008 Strasbourg Cedex, France.
Miesch
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M