title: Prostate pathology: histologic and molecular perspectives.
abstract: The field of prostate cancer research is poised for dramatic improvements in our ability to better diagnose men at risk of prostate cancer and to better predict prognosis and response to treatment. Histopathologic and molecular analyses lie at the heart of these issues. Improvements in our understanding of the mechanisms of prostate carcinogenesis and in determining why the prostate seems to be so highly targeted for cancer development will lead to rational strategies of disease prevention.
authors.affiliation: Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Putzi
authors.forename: A M
authors.initials: AM
authors.lastname: De Marzo
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D017668:Age of Onset; D000368:Aged; D001284:Atrophy; D014408:Biomarkers, Tumor / Q000032:analysis; D001707:Biopsy, Needle / Q000379:methods; D006801:Humans; D006965:Hyperplasia; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009363:Neoplasm Proteins / Q000032:analysis; D011379:Prognosis; D011467:Prostate / Q000737:chemistry / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood; D019048:Prostatic Intraepithelial Neoplasia / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D011472:Prostatitis / Q000097:blood / Q000473:pathology; D013194:Staining and Labeling / Q000379:methods
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D017430:Prostate-Specific Antigen