title: Avoiding intubation in the injured subglottis: the role of heliox therapy.
abstract: Intubation in the child presenting with severe viral tracheobronchitis or prior subglottic injury can be detrimental to the child and the subglottis. Intubation may lead to further mucosal ischemia, scar, subglottic stenosis, or failed extubation requiring a tracheotomy. Heliox is a combination of helium and oxygen that produces less-dense gas exchange. Its use leads to a decrease in turbulent airflow, which may obviate the need for intubation. Here we report our experience using heliox as initial therapy in 14 consecutive children presenting with severe airway distress and the need for intubation. (Five had viral tracheobronchitis, 5 had inflammatory exacerbation of subglottic stenosis, and 4 had acute iatrogenic subglottic injury.) In 10 of the 14 children, intubation, which can lead to mucosal injury and scarring, was avoided by the use of heliox therapy. Of the 4 children in whom heliox therapy failed, 3 had a prior history of subglottic stenosis. Heliox is a relatively safe and reliable alternative to intubation of children with severe subglottic edema or injury. Heliox should be considered before intubation for selected children with subglottic inflammation and severe airway distress.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Wake Forest University Baptist Medical Center-Brenner Children's Hospital, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
authors.forename: K M
authors.initials: KM
authors.lastname: Connolly
authors.forename: W F
authors.initials: WF
authors.lastname: McGuirt
mesh_terms: D001990:Bronchiolitis, Viral / Q000150:complications; D002675:Child, Preschool; D005260:Female; D005931:Glottis / Q000293:injuries / Q000473:pathology; D006371:Helium / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal / Q000009:adverse effects; D007829:Laryngostenosis / Q000150:complications; D008297:Male; D010100:Oxygen / Q000008:administration & dosage* / Q000627:therapeutic use; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy*
chemical_list: D006371:Helium; C038949:heliox; D010100:Oxygen