title: Fatal hepatitis associated with isoflurane exposure and CYP2A6 autoantibodies.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Martin
authors.forename: M T
authors.initials: MT
authors.lastname: Keegan
authors.forename: G M
authors.initials: GM
authors.lastname: Vasdev
authors.forename: S L
authors.initials: SL
authors.lastname: Nyberg
authors.forename: M
authors.initials: M
authors.lastname: Bourdi
authors.forename: L R
authors.initials: LR
authors.lastname: Pohl
authors.forename: D J
authors.initials: DJ
authors.lastname: Plevak
mesh_terms: D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D001189:Aryl Hydrocarbon Hydroxylases; D001323:Autoantibodies / Q000097:blood*; D056486:Chemical and Drug Induced Liver Injury / Q000276:immunology / Q000473:pathology*; D065637:Cytochrome P-450 CYP2A6; D003577:Cytochrome P-450 Enzyme System / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D017809:Fatal Outcome; D006801:Humans; D007530:Isoflurane / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D006899:Mixed Function Oxygenases / Q000276:immunology*
chemical_list: D018685:Anesthetics, Inhalation; D001323:Autoantibodies; D003577:Cytochrome P-450 Enzyme System; D007530:Isoflurane; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; C585710:CYP2A6 protein, human; D065637:Cytochrome P-450 CYP2A6