[Monoclonal antibodies for studying antigens of protein origin in serotyping of Yersinia pseudotuberculosis].
Hybridomas producing monoclonal antibodies (MAb) to Yersinia pseudotuberculosis, serovars I-IV, responsible for serovar appurtenance, were obtained. Virtually all MAbs reacted with protein antigens in immunoblotting. The only exclusion was MAb 3A2 presumably reacting with a glycoprotein epitope of complex structure. Variability of Y. pseudotuberculosis antigenic structure, depending on culturing temperature, was confirmed. Polypeptides with mono- or polydetermined antigenic specificity were determined using MAbs.
Fedorova
V A
VA
Mikrob Plague Control Institute, Saratov.
Sameliia
Zh G
ZhG
Devdariani
Z L
ZL
Shvedun
G P
GP
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis; D000918:Antibody Specificity; D000942:Antigens, Bacterial / Q000276:immunology*; D000939:Epitopes; D051379:Mice; D008807:Mice, Inbred BALB C; D015011:Yersinia pseudotuberculosis / Q000145:classification* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000939:Epitopes
Monoklonal'nye antitela dlia izucheniia roli antigenov belkovoĭ prirody v serotipirovanii bakteriĭ Yersinia pseudotuberculosis.