Mild oxidative one-pot allyl group cleavage.
[reaction: see text]. A new one-pot method is described for the removal of O- and N-allyl protecting groups under oxidative conditions at near neutral pH. The allyl group undergoes hydroxylation and subsequent periodate scission of the vicinal diol, followed by repetition of this reaction sequence on the enolic form of the aldehyde intermediate.
Kitov
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Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2G2.
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