Comments to paper by S. Rattan: applying hormesis in aging research and therapy--a perspective from evolutionary biology.
The phenomenon of hormesis is discussed from an evolutionary biology perspective, i.e. in a context of fitness. Some of the evolutionary theories of aging are outlined. The influence of associations between traits and their environmental specificity is highlighted. Questions about consistency of the impact of hormetic agents across life stages are raised and finally the uniformity of definitions across disciplines is shortly discussed.
Hercus
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Department of Ecology and Genetics, University of Aarhus, Denmark.
Loeschcke
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D000222:Adaptation, Physiological; D000375:Aging / Q000235:genetics* / Q000502:physiology*; D000818:Animals; D005075:Biological Evolution; D006706:Homeostasis; D006801:Humans; D008136:Longevity / Q000235:genetics / Q000502:physiology; D010641:Phenotype