title: Pulmonary sequelae after electron spinal irradiation.
abstract: We measured pulmonary function in 21 patients, after craniospinal irradiation with a posterior spinal electron beam. The median age at treatment was 7.5 years. Nine patients (43%) demonstrated abnormal pulmonary function tests, five with restrictive changes, one with isolated diminished diffusion capacity, and three with obstructive disease. These changes were mild and predominantly asymptomatic.
authors.affiliation: Department of Radiation Oncology, Torrance Memorial Medical Center, 3330 Lomita Boulevard, Torrance, CA 90505, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Endicott
authors.forename: B J
authors.initials: BJ
authors.lastname: Fisher
authors.forename: E
authors.initials: E
authors.lastname: Wong
authors.forename: N A
authors.initials: NA
authors.lastname: Paterson
authors.forename: L E
authors.initials: LE
authors.lastname: Gaspar
authors.forename: M
authors.initials: M
authors.lastname: Bauman
mesh_terms: D000293:Adolescent; D000328:Adult; D016543:Central Nervous System Neoplasms / Q000532:radiotherapy*; D002648:Child; D002675:Child, Preschool; D016371:Cranial Irradiation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000532:radiotherapy; D017564:Radiation Pneumonitis; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*; D012129:Respiratory Function Tests; D013131:Spine