Serum ferritin and other haematological measurements in apparently healthy children with malaria parasitaemia in Lagos, Nigeria.
One hundred apparently normal nursery and primary school children aged between 2 to 12 years from private schools, in Lagos Nigeria were studied. From this study the mean ferritin levels for children aged 2-5 years, and 6-12 years were 112 +/- 48 micrograms/l, and 119 +/- 38 micrograms/l respectively. Mean haematocrit values were 37.6 +/- 2.2%, and 37.5 +/- 2.6%, while mean haemoglobin levels were 126 +/- 9 g/l 127 +/- 7.9 g/l (2-5 years and 6-12 years respectively). The mean values for MCV, MCH, MCHC were 92 +/- 8.6 fl, 27.6 +/- 3.0 pg, 338.0 +/- 15.0 g/l and 93.5 +/- 9.0 fl, 28.7 +/- 2.5 pg, 332.0 +/- 17.0 g/l (2-5 years and 6-12 years respectively). All haematological parameters measured were similar in both malaria parasitaemia positive and negative subjects, except ferritin level which was significantly higher in subjects with malaria parasitaemia (p < 0.05). There was positive correlation between ferritin concentration and malaria density (r = 0.85, p < 0.05). From the above findings, it would be concluded that, ferritin estimation without examination for malaria parasitaemia in a malarious region like Nigeria is not reliable. It is also concluded that with the high mean ferritin level obtained in this study for normal children on balanced diet, routine iron supplementation may not be necessary for this group of children in Nigeria.
Odunukwe
N N
NN
Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Salako
L A
LA
Okanny
C
C
Ahmed
O A
OA
Mafe
A G
AG
Efinemokwu
C
C
Raheem
T Y
TY
D002648:Child; D015362:Child Nutrition Disorders / Q000097:blood* / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology; D002675:Child, Preschool; D019353:Endemic Diseases / Q000706:statistics & numerical data; D004909:Erythrocyte Indices; D005260:Female; D005293:Ferritins / Q000097:blood*; D006400:Hematocrit; D006801:Humans; D007501:Iron / Q000097:blood; D016014:Linear Models; D008288:Malaria / Q000097:blood* / Q000150:complications / Q000453:epidemiology / Q000469:parasitology*; D008297:Male; D009549:Nigeria / Q000453:epidemiology; D014504:Urban Health / Q000706:statistics & numerical data
D005293:Ferritins; D007501:Iron