title: Incidence of mastitis in beef cows after intramuscular administration of oxytetracycline.
abstract: There is limited information on the value of antibiotic therapy for mastitis in beef cows. Effects of antibiotic treatment at weaning and the subsequent calving on calf weaning weight, milk somatic cell counts, milk components, and intramammary infection were studied in beef cows. Additionally, effects of number of infected mammary quarters, number of dry mammary quarters, type of intramammary pathogen, and parity on response variables were determined. Cows (n = 192) were randomly assigned to treatments in a 2 x 2 factorial arrangement; factors were time of treatment (weaning and after calving) and treatment (vehicle and vehicle plus antibiotic). Oxytetracycline (LA-200) or vehicle was administered intramuscularly following collection of quarter milk samples at weaning and calving. Percentage of infected cows and quarters averaged 43.4 and 16.4%, respectively, at calving and increased (P < 0.05) to 53.7 and 29.7% at weaning. Calves from cows with one or two dry quarters weighed 12.7 kg less (P < 0.05) at 90 d after calving and 18.7% less (P < 0.05) at 212 d after calving than calves from cows with no dry quarters. Calves from cows with three or four infected quarters weighed 17.5 kg less (P < 0.05) at 90 d and 25.5 kg less (P < 0.05) at weaning than calves from cows with two or fewer infected quarters. Infections by Staphylococcus aureus and coagulase-negative staphylococci were the most common and accounted for 67 and 78% of the infections. Percentages of infected cows and quarters, infections caused by S. aureus, and dry quarters increased (P < 0.05) with parity. No differences were found among antibiotic treatments for any of the response variables studied. Intramuscular oxytetracycline was not effective in the control of mastitis in beef cows under the conditions of the study.
authors.affiliation: Department of Animal and Avian Sciences, University of Maryland, College Park 20742, USA.
authors.forename: M I
authors.initials: MI
authors.lastname: Dueñas
authors.forename: M J
authors.initials: MJ
authors.lastname: Paape
authors.forename: R P
authors.initials: RP
authors.lastname: Wettemann
authors.forename: L W
authors.initials: LW
authors.lastname: Douglass
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001835:Body Weight; D002417:Cattle; D005260:Female; D015994:Incidence; D007273:Injections, Intramuscular; D008414:Mastitis, Bovine / Q000453:epidemiology* / Q000517:prevention & control; D008892:Milk / Q000737:chemistry; D009825:Oklahoma / Q000453:epidemiology; D010118:Oxytetracycline / Q000627:therapeutic use*; D014886:Weaning
chemical_list: D000900:Anti-Bacterial Agents; D010118:Oxytetracycline