title: Birth after intracytoplasmic sperm injection with use of testicular sperm from men with Kartagener/immotile cilia syndrome.
abstract: OBJECTIVE
  To describe two cases of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndromes.
  
  
  METHODS
  Case report.
  
  
  METHODS
  A university-based male infertility clinic and assisted reproduction unit.
  
  
  METHODS
  Two couples with male factor infertility due to Kartagener/immotile cilia syndrome.
  
  
  METHODS
  IVF/ICSI with testicular sperm.
  
  
  METHODS
  Semen characteristics, sperm viability, fertilization rate, and pregnancy.
  
  
  RESULTS
  With testicular sperm, the two pronuclear fertilization rates were 63% and 60% in two cases. One case resulted in the birth of normal healthy girl.
  
  
  CONCLUSIONS
  With testicular sperm, successful oocyte fertilization after ICSI in couples with male Kartagener/immotile cilia syndrome is possible despite the lack of sperm motility.
authors.affiliation: Department of Urology, University of California San Francisco School of Medicine, San Francisco, CA 94115-1695, USA.
authors.forename: S
authors.initials: S
authors.lastname: Cayan
authors.forename: J
authors.initials: J
authors.lastname: Conaghan
authors.forename: E D
authors.initials: ED
authors.lastname: Schriock
authors.forename: I P
authors.initials: IP
authors.lastname: Ryan
authors.forename: L D
authors.initials: LD
authors.lastname: Black
authors.forename: P J
authors.initials: PJ
authors.lastname: Turek
mesh_terms: D000328:Adult; D002925:Ciliary Motility Disorders / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007619:Kartagener Syndrome / Q000503:physiopathology*; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D013076:Sperm Count; D020554:Sperm Injections, Intracytoplasmic; D013081:Sperm Motility; D013094:Spermatozoa / Q000502:physiology*; D013737:Testis