Primary vulvar adenocarcinoma of cloacogenic origin.
A 43-year-old woman who had a vulvar mass associated with mild discomfort was found to have a rare primary vulvar adenocarcinoma of probable cloacal origin. The tumor was contiguous with the surface epithelium of the vulva and was a well to moderately differentiated adenocarcinoma of colonic type. Stains of the neoplastic cells were positive for both acid and neutral mucin, and periodic acid-Schiff (PAS) was positive after diastase reaction. The neoplastic cells were strongly positive for carcinoembryonic antigen, broad spectrum cytokeratin, and p-53 antigen. Clinical evaluation failed to show any primary tumor in colon, lung, or breast. The patient was disease free 18 months after operation.
Zaidi
S N
SN
Department of Pathology, University of Alabama at Birmingham, 35233, USA.
Conner
M G
MG
D000230:Adenocarcinoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D000328:Adult; D002988:Cloaca; D005260:Female; D006801:Humans; D014846:Vulvar Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery