title: [Cervical lymph node involvement in laryngeal carcinoma: a retrospective study of 430 cases].
abstract: Cervical lymph node involvement in laryngeal tumors could be a market impact on the disease prognosis. We performed a retrospective study of 430 patients who underwent surgery to treat laryngeal carcinoma in our center over a 10-year period. The objective was to correlate clinical and pathological lymph node involvement with the site of origin and size of the tumor, the treatment and its impact on patient survival. We observed a significantly greater incidence of lymph node involvement in tumors originating from supraglottis, with a rate of occult lymph node metastases of 31%. Patients with lymphadenopathy that remained undetected in the absence of surgical treatment and those with nonmetastatic lymphadenopathy presented similar 5-year survival rates, 83% y 98% respectively. However, the 5-year survival decreased to 24% in the presence of metastatic lymph node involvement. These results support the proposal that treatment of laryngeal carcinoma should include the region of the cervical nodes as well.
authors.affiliation: Servicio de O.R.L. Clínica Puerta de Hierro, Universidad Autónoma de Madrid.
authors.forename: M
authors.initials: M
authors.lastname: Pinilla
authors.forename: F M
authors.initials: FM
authors.lastname: Gónzalez
authors.forename: C
authors.initials: C
authors.lastname: López-Cortijo
authors.forename: J
authors.initials: J
authors.lastname: Vicente
authors.forename: C
authors.initials: C
authors.lastname: Górriz
authors.forename: D
authors.initials: D
authors.lastname: Laguna
authors.forename: R
authors.initials: R
authors.lastname: De la Fuente
authors.forename: J
authors.initials: J
authors.lastname: Vergara
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009333:Neck; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012189:Retrospective Studies
vernacular_title: Afectación ganglionar cervical en el carcinoma laríngeo. Un estudio retrospectivo de 430 casos.