Strong 1,4-P-O intramolecular interactions as a source of conformational preferences in alpha-stabilized phosphorus ylides.
For the first time, the existence of a strong intramolecular 1,4-interaction between the phosphorus atom and the oxygen atom in alpha-keto-stabilized ylides has been demonstrated by means of theoretical calculations. This interaction has a notable influence on the conformational preferences and rotational barriers of alpha-stabilized phosphorus ylides and bis-ylides.
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Departament de Química, Edifici C.n., Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. agusti@klingon.uab.es
Carbó
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Urriolabeitia
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