title: Cryptococcus neoformans var. neoformans (serotype D) strains are more susceptible to heat than C. neoformans var. grubii (serotype A) strains.
abstract: Cryptococcus neoformans var. neoformans (serotype D) and C. neoformans var. grubii (serotype A) differ in geographic prevalence and dermatotropism, with C. neoformans var. neoformans strains being more prevalent among isolates from temperate countries as well as from skin infections. Analysis of 19 strains from each serotype revealed wide variation in thermal susceptibility, with C. neoformans var. neoformans strains being more susceptible, on average, to heat killing. The results suggest a consistent explanation for the geographic differences between serotype A and D strains and for the dermatotropism of serotype D strains.
authors.affiliation: Department of Biology, Long Island University, Brooklyn, New York, USA.
authors.forename: L R
authors.initials: LR
authors.lastname: Martinez
authors.forename: J
authors.initials: J
authors.lastname: Garcia-Rivera
authors.forename: A
authors.initials: A
authors.lastname: Casadevall
mesh_terms: D015169:Colony Count, Microbial; D003453:Cryptococcosis / Q000382:microbiology; D003455:Cryptococcus neoformans / Q000145:classification / Q000502:physiology*; D003470:Culture Media; D006358:Hot Temperature; D006801:Humans; D012703:Serotyping
chemical_list: D003470:Culture Media