title: Deltamethrin tolerance & associated cross resistance in Aedes aegypti from Mysore.
abstract: OBJECTIVE
  The indiscriminate use of insecticides in public health and agriculture has led to the development of resistance to these insecticides in the vector mosquitoes. To understand the development of resistance to synthetic pyrethroids, selection studies on Aedes aegypti were done at Mysore.
  
  
  METHODS
  Ae. aegypti collected from the field were subjected to selection experiment with deltamethrin for 16 generations in the laboratory. Cross resistance test was conducted against permethrin and fenvalerate.
  
  
  RESULTS
  Tolerance level was found to increase by 333.83 folds in terms of its LC50 values. Cross resistance of this deltamethrin selected line was tested against permethrin and fenvalerate. The results show that the selected line has developed cross resistance as much as 5.19 and 5.92 folds respectively against permethrin and fenvalerate.
  
  
  CONCLUSIONS
  The findings show a continuous elevation in tolerance in Ae. aegypti with increase in deltamethrin selection pressure, and development of cross resistance to other insecticides of the same class. The natural or developed tolerance has its implications in the control of these mosquitoes.
authors.affiliation: Department of Studies in Zoology, University of Mysore, Mysore, India.
authors.forename: J
authors.initials: J
authors.lastname: Urmila
authors.forename: V A
authors.initials: VA
authors.lastname: Vijayan
authors.forename: K N
authors.initials: KN
authors.lastname: Ganesh
authors.forename: N
authors.initials: N
authors.lastname: Gopalan
authors.forename: S
authors.initials: S
authors.lastname: Prakash
mesh_terms: D000330:Aedes; D000818:Animals; D004351:Drug Resistance; D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins
chemical_list: D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin