(-)-Terpestacin and L-tenuazonic acid, inducers of pigment and aerial mycelium formation by Fusarium culmorum JP 15.
Surface cultures of Fusarium culmorum JP15 were found to respond to extracts of other fungi by enhanced production of orange-red fusarubin pigments and formation of aerial mycelium. Two inducers from strain Ulocladium sp. HKI 0226, the new (-)-terpestacin (1) and L-tenuazonic acid (2), were isolated. 1 inhibited syncytium formation by cells infected with respiratory syncytial virus (RSV).
Schlegel
B
B
Department of Biostructure Chemistry, Hans-Knöll-Institute for Natural Products Research, Beutenbergstrasse 11, D-07745 Jena, Germany.
Schmidtke
M
M
Dörfelt
H
H
Kleinwächter
P
P
Gräfe
U
U
D001643:Bridged Bicyclo Compounds / Q000378:metabolism*; D003470:Culture Media; D005670:Fusarium / Q000254:growth & development*; D013058:Mass Spectrometry / Q000379:methods; D009024:Morphogenesis; D010860:Pigments, Biological / Q000096:biosynthesis*; D012136:Respiratory Syncytial Viruses / Q000502:physiology; D013720:Tenuazonic Acid / Q000378:metabolism*
D001643:Bridged Bicyclo Compounds; D003470:Culture Media; D010860:Pigments, Biological; C080890:terpestacin; D013720:Tenuazonic Acid