title: Accelerated atheroma, antiphospholipid antibodies, and the antiphospholipid syndrome.
abstract: Indirect data coming from animal studies and in vitro observations support the contention that the mere presence of antiphospholipid antibodies may be sufficient to increase atheroma development, regardless of other predisposing factors. It seems that humoral and cellular immune responses to beta 2-glycoprotein I can play an important role in mediating the increased propensity to atherosclerosis.
authors.affiliation: Department of Cardiology, Tel Aviv Medical Center, Tel Aviv, Israel.
authors.forename: J
authors.initials: J
authors.lastname: George
authors.forename: D
authors.initials: D
authors.lastname: Haratz
authors.forename: Y
authors.initials: Y
authors.lastname: Shoenfeld
mesh_terms: D017152:Antibodies, Antiphospholipid / Q000276:immunology*; D016736:Antiphospholipid Syndrome / Q000276:immunology* / Q000503:physiopathology; D001161:Arteriosclerosis / Q000503:physiopathology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000276:immunology
chemical_list: D017152:Antibodies, Antiphospholipid; D019038:Platelet Glycoprotein GPIb-IX Complex