Wingless signalling: more about the Wingless morphogen.
Recent work on pattern formation in the Drosophila embryo reveals a new mechanism which shapes the gradient of the secreted morphogen, Wingless: Wingless protein is degraded more rapidly on one side of its source than on the other.
Lawrence
P A
PA
MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
D000818:Animals; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000166:cytology / Q000196:embryology* / Q000235:genetics; D004815:Epidermal Growth Factor / Q000378:metabolism; D009024:Morphogenesis / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000235:genetics / Q000378:metabolism*; D051155:Wnt1 Protein
D029721:Drosophila Proteins; D011518:Proto-Oncogene Proteins; D051155:Wnt1 Protein; C074622:wg protein, Drosophila; D004815:Epidermal Growth Factor