title: Cyclic hexapeptides with free carboxylate groups as new receptors for monosaccharides.
abstract: [structure: see text]. Cyclic hexapeptides composed of alternating L-proline and 3-aminobenzoic acid subunits with substituents on the aromatic subunits that contain free carboxylate groups are able to bind monosaccharides in 4% CD3OD/CDCl3. The binding selectivity of these peptides depends on the structure of the substituents on the aromatic subunits.
authors.affiliation: Institut für Organische Chemie und Makromolekulare Chemie, Heinrich-Heine-Universität, Universitätsstr. 1, D-40225 Düsseldorf, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Bitta
authors.forename: S
authors.initials: S
authors.lastname: Kubik
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D002352:Carrier Proteins / Q000737:chemistry / Q000378:metabolism*; D009005:Monosaccharides / Q000378:metabolism*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010456:Peptides, Cyclic / Q000737:chemistry / Q000378:metabolism*; D011485:Protein Binding; D011956:Receptors, Cell Surface
chemical_list: D002264:Carboxylic Acids; D002352:Carrier Proteins; D009005:Monosaccharides; D010456:Peptides, Cyclic; D011956:Receptors, Cell Surface; C055213:saccharide-binding proteins