title: [3-years' study of family contacts of HBsAg+ individuals].
abstract: BACKGROUND
  About 50,000 HbsAg carriers exist in Czech Republic. The most endangered group is the family members and sex partners. On the basis of positive HbsAg laboratory findings we decided to offer laboratory examination of post-infectious hepatic markers and to sero-negative also the vaccination against viral hepatitis B.
  
  
  RESULTS
  The group of HbsAg carriers included 453 persons (253 males and 200 females), average age 42.3 years, within the range of 0 to 89 years. When samples were taken, 55.4% of examined persons were classified as "Healthy carrier". To offer of free examination and vaccination 410 family contacts responded. Postinfectious markers (HbsAg, antiHbsAg) were identified in 19.0% of examined persons, 78.3% of sensitive ones were vaccinated. When financial costs were evaluated, it is possible to conclude that examination and vaccination of contacts of HbsAg positive persons in the whole Czech Republic using the same method and similar collaboration may require 58.5 millions Kc. When laboratory tests were omitted, the costs may be reduced to 59.4%.
  
  
  CONCLUSIONS
  On the basis of presented data authors deduce that the legislation of Czech Republic should be quickly changed to include the precept of free vaccination of family contacts of HbsAg positive persons. In accordance with it, rational method of depistage of those persons and information transfer should be developed. Considering long-term consequences of the viral B hepatitis, unreplaceable role in the prevention and diagnostics of the infection have general practitioners.
authors.affiliation: Oddĕlení epidemiologie KHS, Plzen. pazdiora@khsplzen.cz
authors.forename: P
authors.initials: P
authors.lastname: Pazdiora
authors.forename: O
authors.initials: O
authors.lastname: Brejcha
authors.forename: A
authors.initials: A
authors.lastname: Kubátová
authors.forename: I
authors.initials: I
authors.lastname: Morávková
authors.forename: R
authors.initials: R
authors.lastname: Ouradová
authors.forename: M
authors.initials: M
authors.lastname: Prechová
authors.forename: M
authors.initials: M
authors.lastname: Spácilová
authors.forename: D
authors.initials: D
authors.lastname: Turková
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State; D002648:Child; D005192:Family Health; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control / Q000635:transmission*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014611:Vaccination
chemical_list: D006514:Hepatitis B Surface Antigens
vernacular_title: Tríleté zkusenosti s vysetrováním rodinných kontaktů HBsAg+ osob.