title: [A case of Bellini duct carcinoma producing granulocyte colony-stimulating factor (G-CSF)].
abstract: A case of Bellini duct carcinoma producing granulocyte colony-stimulating factor (G-CSF) is reported. The patient was a 75-year-old female with the chief complaint of appetite loss. Abdominal ultrasonography and abdominal computed tomography revealed left renal pelvic tumor. Left radical nephrouretrectomy was performed. The histopathological report showed Bellini duct carcinoma. Immunohistochemical staining using the anti-G-CSF antibody showed positive staining in the cancer cells. Preoperatively, the white blood cell count and serum G-CSF concentration were elevated to 34,100/microliter and 334 pg/ml respectively. After operation these values became normal. However, these values were elevated again and CT scan revealed a left pulmonary metastasis 3 months after the operation. In spite of chemotherapy, she died of brain metastases 7 months after the operation.
authors.affiliation: Department of Urology, Toranomon Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Morikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: H
authors.initials: H
authors.lastname: Oda
authors.forename: K
authors.initials: K
authors.lastname: Kitahara
authors.forename: M
authors.initials: M
authors.lastname: Kanemura
authors.forename: H
authors.initials: H
authors.lastname: Komatsu
authors.forename: S
authors.initials: S
authors.lastname: Kawagoe
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D000368:Aged; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D007685:Kidney Tubules, Collecting; D009392:Nephrectomy; D014513:Ureter / Q000601:surgery
chemical_list: D016179:Granulocyte Colony-Stimulating Factor