Multicenter proficiency testing of nucleic acid amplification methods for the detection of enteroviruses.
A multicenter study of molecular detection of enteroviruses was conducted using a proficiency panel. Of 70 data sets, 46 (66%) reported correct results for samples containing at least 1 50% infective dose per ml and for negative samples. Variation in performance between laboratories demonstrates the need for ongoing quality control.
Van Vliet
K E
KE
Department of Virology, University Medical Center Utrecht, Utrecht, The Netherlands.
Muir
P
P
Echevarria
J M
JM
Klapper
P E
PE
Cleator
G M
GM
Van Loon
A M
AM
D004770:Enterovirus / Q000235:genetics / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D007753:Laboratories / Q000592:standards*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods* / Q000592:standards; D011786:Quality Control; D012367:RNA, Viral / Q000032:analysis
D012367:RNA, Viral