title: [Major mRNP proteins in the structural organization and function of mRNA in eukaryotic cells].
abstract: The properties of two universal major proteins of cytoplasmic mRNP, p50 and the poly(A)-binding protein (PABP), are summarized. Their roles in formation of polyribosomal and free inactive mRNP are considered, with the focus on the authors' studies of p50. The parts these mRNP proteins play in translation regulation, stability, and localization of mRNA are described, and the the possible mechanisms of their function are discussed.
authors.affiliation: ovchinn@vega.protres.ru
authors.forename: L P
authors.initials: LP
authors.lastname: Ovchinnikov
authors.forename: M A
authors.initials: MA
authors.lastname: Skabkin
authors.forename: P V
authors.initials: PV
authors.lastname: Ruzanov
authors.forename: V M
authors.initials: VM
authors.lastname: Evdokimova
mesh_terms: D000818:Animals; D005057:Eukaryotic Cells; D006801:Humans; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000737:chemistry / Q000502:physiology*; D012261:Ribonucleoproteins / Q000737:chemistry / Q000502:physiology*; D012270:Ribosomes / Q000502:physiology
chemical_list: D012333:RNA, Messenger; D012261:Ribonucleoproteins; C026452:messenger ribonucleoprotein
vernacular_title: Mazhornye belki mRNP v strukturnoĭ organizatsii i funktsionirovanii mRNK v kletkakh éukariot.