title: [Percentage of tumor in prostatic biopsy cylinders as prognosis factor of organ-limited disease in candidates for radical prostatectomy].
abstract: The present study analyzes the prognostic influence of tumor percentage in cylinders of prostatic biopsy in this patient group.
  
  
  METHODS
  Retrospective study of 68 patients with a diagnosis of adenocarcinoma, clinical stage T1-T2 who had undergone a radical prostatectomy from May 1997 to october 2000. Following preoperative parameters were analyzed: age, PSA, clinical staging, Gleason and six cylinders of ultrasonography-leaded transrectal prostatic biopsy, studying the amount of positive biopsies, the tumor percentage of the total amount of biopsies and the maximum percentage of tumor in one cylinder. Univariate (square-Chi, Student t) and multivariate (multiple logistic regression) analysis are performed in order to study the relationship of these parameters with the presence or not of an organ-located disease.
  
  
  RESULTS
  An organ-located disease was shown at 44 patients through the piece of radical prostatectomy. The univariate analysis gave all studied parameters, except age, a prognostic value of the existence or not of an organ-located disease. In the multivariate analysis only the total percentage of biopsy tumors (p = 0.0002) and PSA (p = 0.005) behaved as independent prognostic factors.
  
  
  CONCLUSIONS
  Tumor percentage in prostatic biopsy seems to be a factor with a high predictive value of an organ-located disease, possibly because it is an index of tumoral volume.
authors.affiliation: Servicio de Urología, Hospital Clínico Universitario, Valencia.
authors.forename: R
authors.initials: R
authors.lastname: Villamón Fort
authors.forename: J M
authors.initials: JM
authors.lastname: Martínez Jabaloyas
authors.forename: M
authors.initials: M
authors.lastname: Gil Salom
authors.forename: M P
authors.initials: MP
authors.lastname: Soriano Sarriá
authors.forename: F
authors.initials: F
authors.lastname: Pastor Hernández
authors.forename: S
authors.initials: S
authors.lastname: Günther
authors.forename: F
authors.initials: F
authors.lastname: García Sisamón
mesh_terms: D000368:Aged; D001706:Biopsy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies
vernacular_title: El porcentaje de tumor en cilindros de biopsia prostática como factor pronóstico de enfermedad órganoconfinada en pacientes candidatos a prostatectomía radical.