title: Principles and history of closed-loop controlled ventilation.
abstract: Respiratory management of intubated patients is a complex problem, even if airway management, sedation, and infection control are excluded and only the limited problem of "how to set a ventilator" is considered. Four dimensions shape the overall strategy for setting a ventilator: time, physiologic task, primary lung disease, and general therapeutic approach. Initiation (start-up), maintenance, and weaning are the principal dimensions in time. This article discusses the closed-loop control method.
authors.affiliation: Marketing Director, Hamilton Medical AG, Rhäzüns, Switzerland. jbrunner@hamilton-medical-ch
authors.forename: J X
authors.initials: JX
authors.lastname: Brunner
mesh_terms: D000465:Algorithms; D004867:Equipment Design; D005246:Feedback; D006801:Humans; D012121:Respiration, Artificial