title: [Finasteride in prolonged therapy of patients with benign prostatic hyperplasia].
abstract: The efficiency of finasteride alone and in combination with alpha 1-adrenoblocker tamsulasine in long (2-4 years) treatment of benign prostatic hyperplasia is analyzed, based on published reports and the author's data. Specific features of long finasteride therapy are discussed: decrease in the level of prostatic specific antigen, no effect in case of concomitant infectious chronic prostatitis, more stable result in combination with tamsulasine, higher efficiency of finasteride after a previous course of therapy for prostatitis. Indications for finasteride therapy are defied. The results of finasteride therapy directly correlate with the size of the prostate in 78% patients.
authors.forename: E B
authors.initials: EB
authors.lastname: Mazo
mesh_terms: D000328:Adult; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D018120:Finasteride / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011470:Prostatic Hyperplasia / Q000188:drug therapy*
chemical_list: D004791:Enzyme Inhibitors; D018120:Finasteride
vernacular_title: Finasterid pri dlitel'nom lechenii bol'nykh s dobrokachestvennoĭ giperplazieĭ prostaty.