title: Infantile acute hemorrhagic edema of the skin.
abstract: Infantile acute hemorrhagic edema (AHE) of the skin is an uncommon form of cutaneous leukocytoclastic vasculitis that occurs in children younger than 3 years. We describe a 10-month-old boy with AHE, in whom the disease appeared after antibiotic treatment for an acute respiratory illness. AHE presented with fever, acral edema, and rosette-shaped purpuric plaques on the face and limbs. The causes of AHE are unclear, as is its nosologic position. Some authors consider the disease as a purely cutaneous form of Henoch-Schönlein purpura, and others believe that AHE should be regarded as a distinct clinicobiologic entity within the spectrum of leukocytoclastic vasculitis.
authors.affiliation: Istituto Dermopatico dell'Immacolata, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Paradisi
authors.forename: G
authors.initials: G
authors.lastname: Annessi
authors.forename: A
authors.initials: A
authors.lastname: Corrado
mesh_terms: D000208:Acute Disease; D001623:Betamethasone / Q000627:therapeutic use; D001707:Biopsy, Needle; D004487:Edema / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D011693:Purpura / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D001623:Betamethasone