title: Mannose-binding lectin polymorphisms in a Canary Islands (Spain) population.
abstract: We have compared the structural and promoter variants of the mannose-binding lectin (MBL) gene in a population from Gran Canaria with that from other populations previously reported. The observed frequencies of the seven alleles of the MBL gene in our population were: HYPA, 0.24; LYQA, 0.22; LYPA, 0.08; LXPA, 0.19; LYPB, 0.17; LYQC, 0.03 and HYPD, 0.07. The frequency of non-producer alleles and of MBL-deficient individuals in our population is higher than in other European and Asian population.
authors.affiliation: Department of Immunology, Hospital de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain.
authors.forename: M I
authors.initials: MI
authors.lastname: García-Laorden
authors.forename: A
authors.initials: A
authors.lastname: Manzanedo
authors.forename: A
authors.initials: A
authors.lastname: Figuerola
authors.forename: F
authors.initials: F
authors.lastname: Sánchez-García
authors.forename: C
authors.initials: C
authors.lastname: Rodríguez-Gallego
mesh_terms: D001266:Atlantic Islands; D002352:Carrier Proteins / Q000235:genetics*; D037222:Collectins; D005260:Female; D006801:Humans; D037102:Lectins / Q000235:genetics; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics*; D013030:Spain; D044465:White People / Q000235:genetics
chemical_list: D002352:Carrier Proteins; D037222:Collectins; D037102:Lectins