title: [Immune and enzyme disorders in patients with acute pancreatitis].
abstract: Analysis of immune and enzyme disorders in 85 patients with acute pancreatitis shows that persistent imbalance of immunoregulatory T-lymphocytes with suppression predominance; reduction of all immunoglobulines number, imbalance in phagocytic immunity with height of absorbing activity of neutropils and stimultaneous decrease of their digestive capacity are prognostically unfavourable for high risk of pyonecrotic complications and lethal outcome.  It is necessary to include immunocorrectors in combined therapy.  Direct assessment of leukocytic elastase activity and alpha-IP level in blood plasma permits to evaluate spreading of inflammatory process and it severity, efficacy and prognosis of treatment.
authors.forename: B S
authors.initials: BS
authors.lastname: Briskin
authors.forename: G A
authors.initials: GA
authors.lastname: Iarovaia
authors.forename: Z I
authors.initials: ZI
authors.lastname: Savchenko
authors.forename: G S
authors.initials: GS
authors.lastname: Rybakov
authors.forename: O Kh
authors.initials: OKh
authors.lastname: Khalidov
authors.forename: L A
authors.initials: LA
authors.lastname: Mkhitarova
authors.forename: A A
authors.initials: AA
authors.lastname: Suplotova
mesh_terms: D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004796:Clinical Enzyme Tests; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D007962:Leukocytes / Q000201:enzymology; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology; D010195:Pancreatitis / Q000175:diagnosis / Q000201:enzymology* / Q000276:immunology* / Q000628:therapy; D010586:Phagocytes / Q000276:immunology; D011379:Prognosis; D012307:Risk Factors; D013601:T-Lymphocytes / Q000276:immunology; D013951:Thymus Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; D000900:Anti-Bacterial Agents; D007136:Immunoglobulins; D013951:Thymus Hormones; C032805:thymalin
vernacular_title: Immunnye i fermentnye narusheniia u bol'nykh ostrym pankreatitom.