A conservative treatment of phimosis in boys.
OBJECTIVE
The aim of this study was to evaluate the efficacy of topical applications of clobetasol propionate cream in the treatment of phimosis in boys and a comparison of the results presented with an overview of the current studies.


METHODS
In a prospective study, 94 boys (mean age 5.5 years) were treated with topical applications of 0.05% clobetasol propionate cream twice daily. The prepuce was treated for 1 month, with an attempt at prepuce retraction after 14 days. The boys were evaluated after 1 month of treatment and every 3 months during follow-up.


RESULTS
Of the 94 boys, 91 were available for follow-up, of whom 42 boys (46.1%) achieved complete retraction of the prepuce, 24 (26.4%) had only preputial adhesions and 4 (4.4%) had partial retraction. Twenty-one boys (23.1%) had no response. The treatment was continued in 13 boys with good results eventually. Seven boys (7.7%) had recurrence after a mean follow-up of 4.3 months (range 2-7). No side effects were noted. Circumcision was necessary in 24 of the 91 boys (26.4%). The mean follow-up was 11.0 months (range 3-18).


CONCLUSIONS
Local application of clobetasol propionate cream is a simple, safe and effective treatment for phimosis in boys and avoids circumcision and its associated risks. It should be offered first instead of circumcision.
ter Meulen
P H
PH
Department of Urology, Atrium Medical Centre, Heerlen, The Netherlands.
Delaere
K P
KP
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D002990:Clobetasol / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D005938:Glucocorticoids; D006801:Humans; D008297:Male; D010688:Phimosis / Q000188:drug therapy*; D011446:Prospective Studies
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D002990:Clobetasol