Rhinovirus RNA in the maxillary sinus epithelium of adult patients with acute sinusitis.
We used in situ hybridization for the detection of rhinovirus in maxillary sinus biopsy specimens obtained from 14 adult patients with acute sinusitis. In 7 specimens, rhinovirus RNA could be demonstrated in the maxillary sinus epithelium, thereby confirming the etiology of rhinovirus and the clinical suspicion of acute sinusitis.
Pitkäranta
A
A
Department of Otorhinolaryngology, University of Helsinki, Helsinki, Finland. anne.pitkaranta@hus.fi
Starck
M
M
Savolainen
S
S
Pöyry
T
T
Suomalainen
I
I
Hyypiä
T
T
Carpen
O
O
Vaheri
A
A
D000208:Acute Disease; D000328:Adult; D004848:Epithelium / Q000821:virology; D005260:Female; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D008443:Maxillary Sinus / Q000821:virology; D015523:Maxillary Sinusitis / Q000821:virology*; D010850:Picornaviridae Infections / Q000821:virology; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification*; D012229:Rhinovirus / Q000235:genetics / Q000302:isolation & purification*
D012367:RNA, Viral