title: Predictors of compliance with neuroleptic medication among inpatients with schizophrenia: a discriminant function analysis.
abstract: OBJECTIVE
  To identify clinically useful predictors of adherence to medication among persons with schizophrenia.
  
  
  METHODS
  We evaluated levels of compliance with neuroleptic medication among 32 consecutive admissions with DSM-III-R schizophrenia from a geographically defined catchment area using a compliance interview. We also assessed symptomatology, insight, neurological status and memory.
  
  
  RESULTS
  Less than 25% of consecutive admissions reported being fully compliant. Drug attitudes were the best predictor of regular compliance, symptomatology the best predictor of noncompliance, and memory the best predictor of partial compliance with neuroleptic medication.
  
  
  CONCLUSIONS
  These data emphasise the complexity of factors that influence whether a person adheres to his medication regimen. Furthermore, they suggest that these factors may vary within the same person over time.
authors.affiliation: Department of Adult Psychiatry, Cluain Mhuire Service, Hospitaller Order John of God, Dublin, Ireland.
authors.forename: G
authors.initials: G
authors.lastname: Donohoe
authors.forename: N
authors.initials: N
authors.lastname: Owens
authors.forename: C
authors.initials: C
authors.lastname: O'Donnell
authors.forename: T
authors.initials: T
authors.lastname: Burke
authors.forename: L
authors.initials: L
authors.lastname: Moore
authors.forename: A
authors.initials: A
authors.lastname: Tobin
authors.forename: E
authors.initials: E
authors.lastname: O'Callaghan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001294:Attitude to Health; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D016002:Discriminant Analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010349:Patient Compliance; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy*; D012720:Severity of Illness Index
chemical_list: D014150:Antipsychotic Agents