Myocardin. a novel potentiator of SRF-mediated transcription in cardiac muscle.
In the June 29, 2001, issue of Cell, Wang et al. report the discovery of myocardin, a cardiac and smooth muscle-specific accessory factor for SRF. This work provides insight into the mechanism of cardiac-specific transcription and suggests the importance of myocardin in early cardiac development.
Hauschka
S D
SD
Department of Biochemistry, University of Washington, 98195, Seattle, WA, USA.
D000818:Animals; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D009206:Myocardium / Q000737:chemistry / Q000378:metabolism*; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D026362:Serum Response Factor; D015534:Trans-Activators / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic; D000099251:Myocardin
D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D026362:Serum Response Factor; D015534:Trans-Activators; D014157:Transcription Factors; D000099251:Myocardin