title: U.S. Public Health Service Guideline on Infectious Disease Issues in Xenotransplantation. Centers for Disease Control and Prevention.
abstract: Several developments have fueled the renewed interest in xenotransplantation--the use of live animal cells, tissues and organs in the treatment or mitigation of human disease. The world-wide, critical shortage of human organs available for transplantation and advances in genetic engineering and in the immunology and biology of organ/tissue rejection have renewed scientists' interest in investigating xenotransplantation as a potentially promising means to treat a wide range of human disorders. This situation is highlighted by the fact that in the United States alone, 13 patients die each day waiting to receive a life-saving transplant to replace a diseased vital organ.
mesh_terms: D000818:Animals; D003140:Communicable Disease Control / Q000592:standards*; D003141:Communicable Diseases / Q000635:transmission; D006801:Humans; D014183:Transplantation, Heterologous / Q000009:adverse effects / Q000592:standards*