[Anesthetic malignant hyperthermia and multiple organ dysfunction syndrome].
The typical explosive form of malignant hyperthermia caused by following isoflurane anaesthesia is a well-known phenomenon. Nevertheless, since dantrolene is used, its evolution toward a multiple organ failure has been rarely described. We report a case of typical explosive malignant hyperthermia caused by an isoflurane anaesthesia complicated by a cardiovascular failure, a disseminated intravascular coagulation, an acute liver failure and an acute renal failure. Afterwards, muscle weakness of the right calf was the only aftermath.
Brossier
T
T
Département d'anesthésie-réanimation, centre hospitalier universitaire, 2, boulevard de Lattre-de-Tassigny, BP 1542, 21034 Dijon, France. t.brossier@libertysurf.fr
Gwinner
N
N
Fontaine
P
P
Girard
C
C
D000328:Adult; D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D002780:Cholestasis, Intrahepatic / Q000503:physiopathology; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000503:physiopathology; D017093:Liver Failure / Q000503:physiopathology; D008111:Liver Function Tests; D008305:Malignant Hyperthermia / Q000209:etiology*; D008738:Methyl Ethers / Q000009:adverse effects*; D009102:Multiple Organ Failure / Q000209:etiology*; D000077149:Sevoflurane
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane
Hyperthermie maligne anesthésique et syndrome de défaillance multiviscérale.