2-substituted furans from Polyalthia suberosa.
Two new 2-substituted furans, 1-(2-furyl)pentacosa-16,18-diyne and 23-(2-furyl)tricosa-5,7-diynoic acid, have been isolated from stems of Polyalthia suberosa. The structures were assigned by spectroscopic methods. The two compounds together with the previously reported kalasinamide, N-trans-feruloyltyramine and N-trans-coumaroyltyramine showed anti-HIV activities.
Tuchinda
P
P
Pohmakotr
M
M
Reutrakul
V
V
Thanyachareon
W
W
Sophasan
S
S
Yoosook
C
C
Santisuk
T
T
Pezzuto
J M
JM
D000480:Alkynes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019380:Anti-HIV Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D053280:Diynes; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry
C438922:1-(2-furyl)pentacosa-16,18-diyne; C438921:23-(2-furyl)tricosa-5,7-diynoic acid; D000480:Alkynes; D019380:Anti-HIV Agents; D053280:Diynes; D005663:Furans