Vascular complications after percutaneous coronary interventions following hemostasis with manual compression versus arteriotomy closure devices.
OBJECTIVE
We evaluated the vascular complications after hemostasis with arteriotomy closure devices (ACD) versus manual compression after percutaneous coronary interventions (PCI).


BACKGROUND
Previous clinical studies have indicated that ACD can be used for achievement of hemostasis and early ambulation after PCI. This study investigated the safety of ACD in achieving hemostasis after PCI compared with manual compression in a large cohort of consecutive patients.


METHODS
A total of 5,093 patients were followed after PCI was performed with the transfemoral approach. Univariate and multivariate analysis were used to identify the predictors of vascular complications with ACD (n = 516) or with manual compression (n = 5,892) as a hemostasis option after sheath removal.


RESULTS
The use of ACD was associated with a more frequent occurrence of hematoma compared with manual compression (9.3 vs. 5.1%, p < 0.001). There was also a higher rate of significant hematocrit drop (>15%) with ACD versus manual compression (5.2% vs. 2.5%, p < 0.001). Similar rates of pseudoaneurysm and arteriovenous fistulae were noted with either hemostasis technique. Vascular surgical repair at the access site was required more often with ACD versus manual compression (2.5 vs. 1.5%, p = 0.03).


CONCLUSIONS
In this early experience with ACD after PCI, their use was associated with higher vascular complication rates than hemostasis with manual compression.
Dangas
G
G
Cardiovascular Research Foundation, Lenox Hill Heart & Vascular Institute, New York, New York, USA.
Mehran
R
R
Kokolis
S
S
Feldman
D
D
Satler
L F
LF
Pichard
A D
AD
Kent
K M
KM
Lansky
A J
AJ
Stone
G W
GW
Leon
M B
MB
D000368:Aged; D017541:Aneurysm, False / Q000209:etiology; D015906:Angioplasty, Balloon, Coronary; D001164:Arteriovenous Fistula / Q000209:etiology; D005260:Female; D005263:Femoral Artery; D006400:Hematocrit; D006406:Hematoma / Q000209:etiology; D006489:Hemostatic Techniques / Q000295:instrumentation; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011677:Punctures / Q000009:adverse effects*; D012189:Retrospective Studies; D014652:Vascular Diseases / Q000209:etiology*