[Characteristics of lymphocyte recirculation through postcapillary venules of lymph node paracortical zone following antigenic stimulation].
The walls of venules of paracortical zone of popliteal lymph nodes were studied in 127 2-5 Ys old male dogs (15-20 kg of body weight) after subcutaneous injection of BCG vaccine 0.2 mg/kg in dose. 6 hrs after the administration of BCG vaccine the venule diameter was found to reduce. Then it gradually increased and returned to initial parameters after 3 months. Lymphocyte number was increased in venular lumen and walls following antigenic treatment. Microvilli number growth was observed in endotheliocytes. Basement membrane in the venules was loosened. Lymphocytes through endotheliocytes. Maximal lymphocyte activity and modifications of venular walls was observed on d 7 following the BCG vaccine administration.
Golovatskiĭ
A S
AS
Department of Human Anatomy, Operative Surgery and Histology, Uzhgorod State University, Ukraine. Department of Human Anatomy, Moscow Medical Academy.
Sapin
M R
MR
D000818:Animals; D001500:BCG Vaccine / Q000276:immunology*; D004285:Dogs; D004730:Endothelium, Vascular / Q000648:ultrastructure; D008198:Lymph Nodes / Q000098:blood supply* / Q000276:immunology; D008214:Lymphocytes / Q000502:physiology*; D008297:Male; D008854:Microscopy, Electron; D014699:Venules / Q000648:ultrastructure
D001500:BCG Vaccine
Osobennosti retsirkuliatsii limfotsitov cherez postkapilliarnye venuly parakortikal'noĭ zony limfaticheskikh uzlov pri antigennoĭ stimuliatsii.