Enantioseparation of hydroxy acids on easy-to-prepare continuous beds for capillary electrochromatography.
This paper deals with the enantioseparation of hydroxy acids by ligand-exchange capillary electrochromatography. A chiral continuous bed was easily prepared by in situ polymerization of monomers, including an L-4-hydroxyproline derivative. This phase showed chiral recognition for several hydroxy acids, in addition to amino acids.
Schmid
M G
MG
Institute of Pharmaceutical Chemistry and Pharmaceutical Technology, Karl-Franzens University, Graz, Austria. schmidm@uni-graz.at
Grobuschek
N
N
Lecnik
O
O
Gübitz
G
G
Végvári
A
A
Hjertén
S
S
D000596:Amino Acids / Q000737:chemistry / Q000302:isolation & purification; D019075:Electrophoresis, Capillary / Q000379:methods*; D006880:Hydroxy Acids / Q000737:chemistry / Q000302:isolation & purification*; D008024:Ligands; D008333:Mandelic Acids / Q000737:chemistry / Q000302:isolation & purification; D011108:Polymers; D013237:Stereoisomerism
D000596:Amino Acids; D006880:Hydroxy Acids; D008024:Ligands; D008333:Mandelic Acids; D011108:Polymers