Langerhans cell granulomatosis: a case report of polyostotic manifestation in the jaw.
We report the case of a 43-year-old woman who suffered from a polyostotic form of Langerhans cell granulomatosis (LCG) in the mandible and maxilla. The course of the disease was followed for more than 14 years. The disease's progression finally required subtotal resection of the mandible and reconstruction with a microvascular fibula graft. The literature is reviewed for diagnostic and treatment concepts based on the different stages of LCG.
Kessler
P
P
Department of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Germany. peter.kessler@mkg.imed.uni-erlangen.de
Wiltfang
J
J
Schultze-Mosgau
S
S
Neukam
F W
FW
D000328:Adult; D016025:Bone Transplantation; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007571:Jaw Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011859:Radiography