title: Response to cancer therapy in a patient with a paraneoplastic choreiform disorder.
abstract: The authors report a patient with chorea and multifocal neurologic abnormalities associated with a small-cell lung carcinoma. A previously unreported antibody directed at a 76-kD neuronal protein antigen was identified in both serum and CSF. Antitumor treatment resulted in dramatic and sustained clinical neurologic and serologic responses.
authors.affiliation: Department of Neurosurgery, Henry Ford Hospital, Detroit, MI 48202, USA.
authors.forename: D
authors.initials: D
authors.lastname: Croteau
authors.forename: A
authors.initials: A
authors.lastname: Owainati
authors.forename: J
authors.initials: J
authors.lastname: Dalmau
authors.forename: L R
authors.initials: LR
authors.lastname: Rogers
mesh_terms: D000818:Animals; D018288:Carcinoma, Small Cell / Q000097:blood / Q000134:cerebrospinal fluid / Q000628:therapy*; D002819:Chorea / Q000097:blood / Q000134:cerebrospinal fluid / Q000628:therapy*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000134:cerebrospinal fluid / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000134:cerebrospinal fluid / Q000628:therapy*; D051381:Rats