A novel polymorphism in the pseudogene TCRBV5S5 combines with TCRBV6S1 to define three haplotypes.
In the current study, we report a G to A single nucleotide polymorphism at base pair 396 of the TCRBV5S5P gene. This polymorphism has a frequency of 0.20 in a cohort of Caucasian controls. In addition, we provide evidence for linkage disequilibrium between TCRBV5S5P and the TCRBV6S1 gene.
Brzezinski
J L
JL
Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0524, USA.
Glass
D N
DN
Choi
E
E
D000483:Alleles; D019674:Genes, T-Cell Receptor beta / Q000235:genetics*; D006239:Haplotypes / Q000276:immunology*; D006801:Humans; D015810:Linkage Disequilibrium / Q000276:immunology; D011110:Polymorphism, Genetic / Q000276:immunology*; D011544:Pseudogenes / Q000235:genetics* / Q000276:immunology*