title: Computer-assisted bone age assessment: image preprocessing and epiphyseal/metaphyseal ROI extraction.
abstract: Clinical assessment of skeletal maturity is based on a visual comparison of a left-hand wrist radiograph with atlas patterns. Using a new digital hand atlas an image analysis methodology is being developed. To assist radiologists in bone age estimation. The analysis starts with a preprocessing function yielding epiphyseal/metaphyseal regions of interest (EMROIs). Then, these regions are subjected to a feature extraction function. Accuracy has been measured independently at three stages of the image analysis: detection of phalangeal tip, extraction of the EMROIs, and location of diameters and lower edge of the EMROIs. Extracted features describe the stage of skeletal development more objectively than visual comparison.
authors.affiliation: Silesian University of Technology, Institute of Electronics, Division of Biomedical Electronics, Gilwice, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Pietka
authors.forename: A
authors.initials: A
authors.lastname: Gertych
authors.forename: S
authors.initials: S
authors.lastname: Pospiech
authors.forename: F
authors.initials: F
authors.lastname: Cao
authors.forename: H K
authors.initials: HK
authors.lastname: Huang
authors.forename: V
authors.initials: V
authors.lastname: Gilsanz
mesh_terms: D000293:Adolescent; D000365:Age Determination by Skeleton; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002348:Carpal Bones / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D003936:Diagnosis, Computer-Assisted; D004838:Epiphyses / Q000000981:diagnostic imaging*; D005260:Female; D006225:Hand / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007223:Infant; D008297:Male; D010012:Osteogenesis