title: Characterization of swine leptin (LEP) polymorphisms and their association with production traits.
abstract: Four polymorphisms in the swine leptin (LEP) gene were characterized and evaluated for association with economically important production traits in Yorkshire, Landrace and Duroc pigs. Our results show that these polymorphisms are generally of low frequency or are absent in pig populations. Two polymorphisms (A2845T and T3469C) may be associated (P < 0.0078) with feed intake and growth rate traits in Landrace pigs.
authors.affiliation: Agriculture and Agri-Food Canada, Dairy and Swine Research and Development Centre, Lennoxville, Quebec, Canada J1M 1Z3.
authors.forename: Y M
authors.initials: YM
authors.lastname: Kennes
authors.forename: B D
authors.initials: BD
authors.lastname: Murphy
authors.forename: F
authors.initials: F
authors.lastname: Pothier
authors.forename: M F
authors.initials: MF
authors.lastname: Palin
mesh_terms: D000483:Alleles; D000818:Animals; D004247:DNA / Q000737:chemistry / Q000235:genetics; D004435:Eating / Q000235:genetics / Q000502:physiology; D020738:Leptin / Q000235:genetics* / Q000502:physiology; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011110:Polymorphism, Genetic / Q000235:genetics* / Q000502:physiology; D012150:Polymorphism, Restriction Fragment Length; D017422:Sequence Analysis, DNA; D013552:Swine / Q000235:genetics* / Q000254:growth & development / Q000502:physiology
chemical_list: D020738:Leptin; D004247:DNA