title: Quantitative regional analysis of myocardial wall motion.
abstract: This paper presents a new technique for semiautomatic quantification of regional heart function from 2-D echocardiography. It uses a novel left ventricular border tracking algorithm based on shape-space ideas that we have recently described. In this paper, we show how to decompose the tracked output into clinically meaningful segmental parameters (wall excursion and thickening), using what we call a computational interpretational space (CIS). This leads to a quantitative and automatic scoring scheme for endocardial excursion and myocardial thickening. The method is illustrated on data from a patient with a myocardial infarct in the apical anterior/inferior region of the heart and is also assessed in a small retrospective dobutamine stress echocardiography clinical case study.
authors.affiliation: Department of Engineering Science, University of Oxford, Oxford, UK.
authors.forename: G
authors.initials: G
authors.lastname: Jacob
authors.forename: J A
authors.initials: JA
authors.lastname: Noble
authors.forename: A D
authors.initials: AD
authors.lastname: Kelion
authors.forename: A P
authors.initials: AP
authors.lastname: Banning
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D004280:Dobutamine; D004452:Echocardiography; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008955:Models, Cardiovascular; D009200:Myocardial Contraction; D016277:Ventricular Function, Left
chemical_list: D004280:Dobutamine