Rats with basolateral amygdala lesions show normal increases in conditioned stimulus processing but reduced conditioned potentiation of eating.
Rats with neurotoxic lesions of basolateral amygdala (ABL) and control rats showed comparable enhancement of attentional processing of a visual stimulus when its predictive value was altered. In contrast, lesioned rats showed less potentiation of eating than did control rats when food was available during presentations of a conditioned stimulus that was previously paired with food. When considered together with previous data, these results indicate a double dissociation between effects of lesions of the ABL and of the amygdala central nucleus on phenomena related to attentional processing and the acquisition of motivational value.
Holland
P C
PC
Department of Psychological and Brain Sciences, Duke University, Durham, North Carolina 27708-0086, USA. pch@duke.edu
Hatfield
T
T
Gallagher
M
M
D000679:Amygdala / Q000473:pathology / Q000502:physiology*; D000818:Animals; D003214:Conditioning, Classical / Q000502:physiology*; D004435:Eating / Q000502:physiology*; D008297:Male; D009042:Motivation; D051381:Rats; D020318:Rats, Long-Evans