title: Malignant otitis externa in an infant with selective IgA deficiency: a case report.
abstract: The occurrence of malignant otitis externa (MOE) in infancy is rare. We report a case of MOE in a neonate who was later identified to have selective IgA deficiency. She was successfully treated with oral ciprofloxacin, but developed external auditory canal stenosis, a deformed pinna, persistent facial nerve palsy, temporal bone erosion and hearing loss. No cases of MOE in selective IgA deficiency have been reported in literature. This is also the first report on the use of ciprofloxacin in infants with MOE.
authors.affiliation: Department of Child Health, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India.
authors.forename: A C
authors.initials: AC
authors.lastname: Paul
authors.forename: A
authors.initials: A
authors.lastname: Justus
authors.forename: A
authors.initials: A
authors.lastname: Balraj
authors.forename: A
authors.initials: A
authors.lastname: Job
authors.forename: C P
authors.initials: CP
authors.lastname: Kirubakaran
mesh_terms: D002675:Child, Preschool; D002939:Ciprofloxacin / Q000008:administration & dosage; D003023:Cloxacillin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D005839:Gentamicins / Q000008:administration & dosage; D006801:Humans; D017098:IgA Deficiency / Q000150:complications / Q000175:diagnosis*; D008795:Metronidazole / Q000008:administration & dosage; D010032:Otitis Externa / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D011552:Pseudomonas Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D005839:Gentamicins; D008795:Metronidazole; D002939:Ciprofloxacin; D003023:Cloxacillin