[Combined effect of insolation and drinking mineral waters on hormonal and immune status in medium-height mountains.(Experimental study)].
80 Wistar male rats were kept for 24 days in moderate altitude conditions of mountain resort Teberda. Before the experiment and after it their blood was examined with enzyme immunoassay for hydrocortisone, T3, T4, TSH, with radioimmunoassay for insulin; glucose levels, dynamics of peripheral blood count, immune status were also measured. It was found that UV radiation has a negative effect on hormonal and immune status of healthy rats in medium-high mountains (hydrocortisone levels fell by 50%, insulin rose 5-6-fold, CIC rose by 24.2%, eosinophils count rose 3-fold, T-cell immunity and lymphocyte phagocyting activity got suppressed, lymphocyte/neutrophil proportion reduced by 35%. Intake of mineral water corrected all the negative effects of insolation but hyperinsulinemia decreased insignificantly.
Polushina
N D
ND
Vasin
V A
VA
Kozhevnikov
S A
SA
Demeshko
N I
NI
D000531:Altitude; D000818:Animals; D006728:Hormones / Q000097:blood*; D007111:Immunity, Cellular; D008297:Male; D008900:Mineral Waters; D009504:Neutrophils / Q000276:immunology; D011863:Radioimmunoassay; D051381:Rats; D017208:Rats, Wistar; D013601:T-Lymphocytes / Q000276:immunology
D006728:Hormones; D008900:Mineral Waters
Sochetannoe deĭstvie insoliatsii i pit'evykh mineral'nykh vod v usloviiakh srednegor'ia na gormonal'nyĭ i immunnyĭ status. (Eksperimental'noe issledovanie).