title: Human knee: in vivo T1(rho)-weighted MR imaging at 1.5 T--preliminary experience.
abstract: A fast spin-echo sequence weighted with a time constant that defines the magnetic relaxation of spins under the influence of a radio-frequency field (T1(rho)) was used in six subjects to measure magnetic resonance (MR) relaxation times in the knee joint with a 1.5-T MR imager. A quantitative comparison of T2- and T1(rho)-weighted MR images was also performed. Substantial T1(rho) dispersion was demonstrated in human articular cartilage, but muscle did not demonstrate much dispersion. T1(rho)-weighted images depicted a chondral lesion with 25% better signal-difference-to-noise ratios than comparable T2-weighted images. This technique may depict cartilage and muscular abnormalities.
authors.affiliation: Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, USA. uduvvuri@mail.med.upenn.edu
authors.forename: U
authors.initials: U
authors.lastname: Duvvuri
authors.forename: S R
authors.initials: SR
authors.lastname: Charagundla
authors.forename: S B
authors.initials: SB
authors.lastname: Kudchodkar
authors.forename: J H
authors.initials: JH
authors.lastname: Kaufman
authors.forename: J B
authors.initials: JB
authors.lastname: Kneeland
authors.forename: R
authors.initials: R
authors.lastname: Rizi
authors.forename: J S
authors.initials: JS
authors.lastname: Leigh
authors.forename: R
authors.initials: R
authors.lastname: Reddy
mesh_terms: D000328:Adult; D002358:Cartilage, Articular; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis; D007719:Knee Joint; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D018482:Muscle, Skeletal; D010146:Pain / Q000175:diagnosis