[About side effects of platinum drugs].
The work presents current view about toxic effects of platinum anticancer drugs. In the first part, the toxic effects of cisplatin as nephrotoxicity, ototoxicity, myelosuppression, anaphylactic-like reactions, neurotoxicity and gastrotoxicity are presented. The second part describes mechanisms of nephrotoxicity of cisplatin. In the third part, the toxicity of carboplatin and iproplatin are reviewed.
Waszkiewicz
K
K
Wydział Chemii Uniwersytetu Wrocławskiego we Wrocławiu.
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D016190:Carboplatin / Q000009:adverse effects; D002945:Cisplatin / Q000009:adverse effects* / Q000494:pharmacology; D004342:Drug Hypersensitivity / Q000209:etiology; D004427:Ear Diseases / Q000139:chemically induced; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced; D009422:Nervous System Diseases / Q000139:chemically induced; D017671:Platinum Compounds / Q000009:adverse effects
D000970:Antineoplastic Agents; D017671:Platinum Compounds; D016190:Carboplatin; D002945:Cisplatin
O skutkach ubocznych podawania leków platynowych.