title: Evaluating causal relations in neural systems: granger causality, directed transfer function and statistical assessment of significance.
abstract: We consider the question of evaluating causal relations among neurobiological signals. In particular, we study the relation between the directed transfer function (DTF) and the well-accepted Granger causality, and show that DTF can be interpreted within the framework of Granger causality. In addition, we propose a method to assess the significance of causality measures. Finally, we demonstrate the applications of these measures to simulated data and actual neurobiological recordings.
authors.affiliation: Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton 33431, USA.
authors.forename: M
authors.initials: M
authors.lastname: Kamiński
authors.forename: M
authors.initials: M
authors.lastname: Ding
authors.forename: W A
authors.initials: WA
authors.lastname: Truccolo
authors.forename: S L
authors.initials: SL
authors.lastname: Bressler
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001921:Brain / Q000166:cytology / Q000502:physiology*; D004569:Electroencephalography; D006801:Humans; D008251:Macaca; D008959:Models, Neurological; D015233:Models, Statistical; D015999:Multivariate Analysis; D009474:Neurons / Q000502:physiology; D012890:Sleep / Q000502:physiology