Radiotherapy in epithelial ovarian cancer: state of the art.
Modern advances in surgery, chemotherapy (CT) and radiotherapy (RT) have not, unfortunately, impacted the overall survival for patients with ovarian cancer (OC). Despite its long history in the treatment of OC and its proven curative role in patients with microscopic or minimal residual disease, the proper role of RT in the management of OC is controversial and not clearly established. Similarly, the potential roles of RT in the consolidative treatment and as salvage therapy following CT failure remain controversial. In the present review current issues in the radiotherapeutic management are discussed along with possible future clinical research directions.
Cardenes
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Department of Radiation Oncology, Indiana University School of Medicine, Indiana 46202, USA.
Randall
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D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D011879:Radiotherapy Dosage; D012107:Research Design; D012307:Risk Factors; D016879:Salvage Therapy / Q000379:methods / Q000592:standards; D016019:Survival Analysis; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology