title: Progressive outer retinal necrosis and acute retinal necrosis in fellow eyes of a patient with acquired immunodeficiency syndrome.
abstract: OBJECTIVE
  To describe an unusual concurrence of acute retinal necrosis and progressive outer retinal necrosis in fellow eyes of a patient with acquired immunodeficiency syndrome (AIDS).
  
  
  METHODS
  Interventional case report. In a 37-year-old man with AIDS and herpes zoster keratitis in the right eye, progressive outer retinal necrosis developed in the right eye and acute retinal necrosis developed in the left eye.
  
  
  RESULTS
  Disparate presentations of retinitis persisted in each eye, and retinal detachment and vision loss ensued in both eyes despite antiviral therapy.
  
  
  CONCLUSIONS
  Distinct features of acute retinal necrosis and progressive outer retinal necrosis do not necessarily reflect systemic factors, and they may be variant manifestations of the same underlying infection.
authors.affiliation: Department of Ophthalmology and Visual Science, Yale University Eye Center, 330 Cedar Street, New Haven, CT 06520, USA. ray.gariano@yale.edu
authors.forename: R F
authors.initials: RF
authors.lastname: Gariano
authors.forename: J P
authors.initials: JP
authors.lastname: Berreen
authors.forename: E L
authors.initials: EL
authors.lastname: Cooney
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000821:virology; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D006563:Herpes Zoster Ophthalmicus / Q000150:complications; D006801:Humans; D008297:Male; D012163:Retinal Detachment / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D015882:Retinal Necrosis Syndrome, Acute / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D012173:Retinitis / Q000150:complications / Q000188:drug therapy / Q000821:virology
chemical_list: D000998:Antiviral Agents