Serum immunoglobulin G antibody responses to Bordetella pertussis lipooligosaccharide and B. parapertussis lipopolysaccharide in children with pertussis and parapertussis.
Serum immunoglobulin G (IgG) antibodies against the lipooligosaccharide (LOS) of Bordetella pertussis and the lipopolysaccharide (LPS) of Bordetella parapertussis were measured by enzyme-linked immunosorbent assay in paired sera from 40 children with pertussis and 14 with parapertussis. Wide differences in the individual responses were noted. Both anti-LOS and -LPS IgG levels increased significantly in the children with pertussis, as did anti-LPS but not anti-LOS in those with parapertussis.
Trollfors
B
B
The Göteborg Pertussis Vaccine Study, The Göteborg Primary Health Care System, Sahlgrenska University Hospital-East, S-416 85 Göteborg, Sweden. birger.trollfors@vgregion.se
Lagergård
T
T
Taranger
J
J
Bergfors
E
E
Schneerson
R
R
Robbins
J B
JB
D000907:Antibodies, Bacterial / Q000096:biosynthesis* / Q000097:blood; D001884:Bordetella / Q000276:immunology*; D001886:Bordetella pertussis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis* / Q000097:blood; D007223:Infant; D008070:Lipopolysaccharides / Q000276:immunology*; D008297:Male; D014917:Whooping Cough / Q000276:immunology*
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D008070:Lipopolysaccharides; C023023:lipid-linked oligosaccharides