Selective sparing of face learning in a global amnesic patient.
OBJECTIVE
To test the hypothesis that visual memory for faces can be dissociated from visual memory for topographical material.


METHODS
A patient who developed a global amnesic syndrome after acute carbon monoxide poisoning is described. A neuroradiological examination documented severe bilateral atrophy of the hippocampi.


RESULTS
Despite a severe anterograde memory disorder involving verbal information, abstract figures, concrete objects, topographical scenes, and spatial information, the patient was still able to learn previously unknown human faces at a normal (and, in some cases, at a higher) rate.


CONCLUSIONS
Together with previous neuropsychological evidence documenting selective sparing of topographical learning in otherwise amnesic patients, this case is indicative of the fact that the neural circuits involved in face recognition are distinct from those involved in the recognition of other visuoperceptual material (for example, topographical scenes).
Carlesimo
G A
GA
IRCCS S Lucia, V. Ardeatina 306, 00179 Rome, Italy. memolab@hsantalucia.it
Fadda
L
L
Turriziani
P
P
Tomaiuolo
F
F
Caltagirone
C
C
D000208:Acute Disease; D000647:Amnesia / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D001284:Atrophy; D002249:Carbon Monoxide Poisoning / Q000150:complications*; D016022:Case-Control Studies; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D020238:Prosopagnosia / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D012720:Severity of Illness Index