Flavon- and flavonolglycosides from Achillea pannonica Scheele.
The detailed investigation of a methanolic extract of aerial parts of Achillea pannonica SCHEELE. within a chemotaxonomic study led to the isolation of 6 flavonoid glycosides. Besides rutin, apigenin-7-O-glucopyranoside, luteolin-7-O-glucopyranoside, apigenin-7-O-rutinoside and acacetin-7-O-rutinoside, an unusual flavondiglucoside was isolated. Its structure was established by UV, 1H NMR and 13C NMR spectroscopic methods including 2D-NMR techniques and ESI-MS as luteolin-7,4'-O-beta-diglucoside. This substance is reported for the first time in the genus Achillea. Chemotaxonomic aspects are discussed briefly.
Kasaj
D
D
Institute of Pharmacognosy, University of Vienna, Pharmacy-Center, Austria.
Krenn
L
L
Prinz
S
S
Hüfner
A
A
Haslinger
E
E
Yu
S S
SS
Kopp
B
B
D019659:Asteraceae / Q000737:chemistry*; D002855:Chromatography, Thin Layer; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D044948:Flavonols; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization
D005419:Flavonoids; D044948:Flavonols; D006027:Glycosides