title: Abnormal thermoregulation in drug-free male schizophrenia patients.
abstract: Schizophrenia patients may develop various thermoregulatory disturbances. We hypothesized that a standardized exercise-heat tolerance test [two 50-min bouts of walking a motor-driven treadmill at 40 degrees C (relative humidity=40%)] would reveal abnormal thermoregulation in drug-free schizophrenia patients. Six drug-free schizophrenia outpatients and seven healthy comparison subjects participated in this study. The schizophrenia patients exhibited significantly higher baseline and exertion-related rectal temperature. The relevance of these findings to the pathophysiology of schizophrenia-related thermoregulatory disorders is as yet unclear.
authors.affiliation: Geha Psychiatric Hospital, Felsenstein Medical Research Center, Beilinson Campus, Petah Tiqva, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Shiloh
authors.forename: A
authors.initials: A
authors.lastname: Weizman
authors.forename: Y
authors.initials: Y
authors.lastname: Epstein
authors.forename: S L
authors.initials: SL
authors.lastname: Rosenberg
authors.forename: A
authors.initials: A
authors.lastname: Valevski
authors.forename: P
authors.initials: P
authors.lastname: Dorfman-Etrog
authors.forename: N
authors.initials: N
authors.lastname: Wiezer
authors.forename: N
authors.initials: N
authors.lastname: Katz
authors.forename: H
authors.initials: H
authors.lastname: Munitz
authors.forename: H
authors.initials: H
authors.lastname: Hermesh
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001831:Body Temperature; D001833:Body Temperature Regulation; D005080:Exercise Test / Q000379:methods; D006339:Heart Rate; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000503:physiopathology*; D012881:Skin Temperature