A new reconstructive procedure after segmental pancreatectomy: an experimental study of pancreatic end-to-end (duct-to-duct) anastomosis.
We produced experimental models of pancreatic end-to-end anastomosis, including ductal end-to-end anastomosis (with or without stent) and pancreaticojejunostomy, using mongrel dogs, with a view to evaluating reconstructive procedures after segmental pancreatectomy. We examined macroscopic findings, pancreatograms, and microangiographic and histopathological findings to determine whether pancreatic end-to-end anastomosis was as practicable as pancreaticojejunostomy. Macroscopic findings showed no suture failure in any animal in the end-to-end anastomosis group. Pancreatography revealed obstruction of the stent tube in the stent subgroup, but good patency in the no-stent subgroup. On the imaging of the microvasculature in the end-to-end anastomosis group, proliferation of neovascular vessels and formation of communicating vessels were detected. Histopathologically, no suture failure was detected, and the viability of the pancreatic end-to-end anastomosis was confirmed. From this experiment, we concluded it that it was possible to employ pancreatic end-to-end anastomosis after segmental pancreatectomy in the clinical situation.
Ota
A
A
Department of Surgery, Division of General and Gastroenterological Surgery, Showa University, School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan.
Kusano
M
M
Ishii
H
H
Hoshino
M
M
Nakamura
A
A
Koike
Y
Y
Enosawa
T
T
Oyama
S
S
D000714:Anastomosis, Surgical / Q000379:methods; D000792:Angiography; D000818:Animals; D004285:Dogs; D023421:Models, Animal; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010180:Pancreatectomy; D010182:Pancreatic Diseases / Q000601:surgery*; D010193:Pancreaticojejunostomy / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D015607:Stents; D013536:Suture Techniques