title: In vivo confocal microscopy of corneal epithelial ingrowth through a laser in situ keratomileusis flap buttonhole.
abstract: We report a case of epithelial ingrowth through a buttonhole 6 months after laser in situ keratomileusis. Elevation topography showed irregular astigmatism and an unreliable pachymetric map. In vivo confocal microscopy showed an epithelial basal cell mosaic with prominent borders and distinct nuclei. No corneal nerves were identified in any image. Cells in the anterior stroma possessed bright, reflective nuclei and appeared to form clusters. The interface between the stromal bed and the flap had formation of nests of fibrotic tissue and epithelial cells.
authors.affiliation: Discipline of Ophthalmology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
authors.forename: C N
authors.initials: CN
authors.lastname: Grupcheva
authors.forename: T Y
authors.initials: TY
authors.lastname: Malik
authors.forename: J P
authors.initials: JP
authors.lastname: Craig
authors.forename: C N
authors.initials: CN
authors.lastname: McGhee
mesh_terms: D000328:Adult; D019781:Corneal Topography; D019573:Epithelium, Corneal / Q000473:pathology*; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008297:Male; D018613:Microscopy, Confocal; D009216:Myopia / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis*; D013524:Surgical Flaps; D014792:Visual Acuity