Amatoxin poisoning from ingestion of Japanese Galerina mushrooms.
BACKGROUND
Although some Japanese Galerina species poisonings manifest as gastrointestinal symptoms followed by late-onset hepatorenal failure (phalloides syndrome), the toxin responsible for this has not been determined.


METHODS
We report a 6-year-old boy who developed characteristic cholera-like diarrhea and late-onset severe hepatic deterioration after eating mushrooms, later identified as a Galerina species, most likely Galerina fasciculata. A residual mushroom revealed alpha-amanitin. This account is the first known reported case of poisoning by Japanese Galerina species where an amatoxin was demonstrated to be responsible for the toxicity.
Kaneko
H
H
Department of Pediatrics, Gunma University School of Medicine, Maebashi, Japan. hkaneko@showa.gunma-u.ac.jp
Tomomasa
T
T
Inoue
Y
Y
Kunimoto
F
F
Fukusato
T
T
Muraoka
S
S
Gonmori
K
K
Matsumoto
T
T
Morikawa
A
A
D000363:Agaricales / Q000737:chemistry*; D000546:Amanitins / Q000032:analysis / Q000506:poisoning*; D002648:Child; D003967:Diarrhea / Q000139:chemically induced; D006801:Humans; D017093:Liver Failure / Q000139:chemically induced; D008111:Liver Function Tests; D008297:Male; D009145:Mushroom Poisoning / Q000150:complications / Q000503:physiopathology*; D013056:Spectrophotometry, Ultraviolet
D000546:Amanitins