title: Hughes (antiphospholipid) syndrome. Clinical features.
abstract: Hughes (antiphospholipid) syndrome is a noninflammatory autoimmune disease. The most critical pathologic process is thrombosis, which results in most of the clinical features suffered by these patients. Recurrent thrombosis together with an adverse pregnancy history and the presence of antiphospholipid antibodies defines the syndrome.
authors.affiliation: Lupus Research Unit, Rayne Institute, St. Thomas' Hospital, London, United Kingdom.
authors.forename: M J
authors.initials: MJ
authors.lastname: Cuadrado
authors.forename: G R
authors.initials: GR
authors.lastname: Hughes
mesh_terms: D017152:Antibodies, Antiphospholipid / Q000032:analysis; D016736:Antiphospholipid Syndrome / Q000175:diagnosis / Q000473:pathology*; D002493:Central Nervous System Diseases / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006402:Hematologic Diseases / Q000209:etiology / Q000473:pathology; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology; D013927:Thrombosis / Q000209:etiology*
chemical_list: D017152:Antibodies, Antiphospholipid