Corticosteroid-induced osteoporosis.
Long-term use of corticosteroids can lead to a change in bone turnover, and thus to a progressive decrease in bone mineral density, which increases the risk of fractures. Up to 50% of patients taking chronic corticosteroids sustain osteoporotic fractures. Although its actual incidence is unknown, corticosteroid-induced osteoporosis is the most common form of drug-related osteoporosis. It is important that nurses become familiar with the diagnostic criteria for corticosteroid-induced osteoporosis and take the necessary steps toward prevention and treatment of this disease.
Lucasey
B
B
Hiatt Osteoporosis Clinic, Division of Endocrinology, University of Kansas Medical Center, Kansas City, Kansas 66160-7318, USA. Blucasey@kumc.edu
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D015519:Bone Density / Q000187:drug effects; D016723:Bone Remodeling / Q000187:drug effects; D050723:Fractures, Bone / Q000209:etiology; D006801:Humans; D015994:Incidence; D010024:Osteoporosis / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D011322:Primary Prevention / Q000379:methods; D012307:Risk Factors; D013256:Steroids; D013997:Time Factors; D016312:Treatment Refusal / Q000523:psychology
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D013256:Steroids