Human papillomavirus associated Bowen's disease of the foot: unique clinical features mimicking a common wart.
We describe a case of Bowen's disease that developed on the left dorsal foot of a 56-year-old female patient and that mimicked the clinical features of a common wart. PCR-based analysis indicated that the lesion contained HPV-16 DNA and HPV-16 positive cells were found in the upper layers of the epidermal lesion using in situ hybridization with an HPV-16 probe.
Mitsuishi
T
T
Department of Dermatology, Tokyo Women's Medical University, 8-1 Kawada-cho Shinjuku-ku, Tokyo 162-8666, Japan. tmitsu@nms.ac.jp
Kawashima
M
M
Sata
T
T
D001913:Bowen's Disease / Q000473:pathology* / Q000821:virology; D004279:DNA, Viral / Q000235:genetics; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics; D030361:Papillomavirus Infections / Q000473:pathology* / Q000821:virology; D012150:Polymorphism, Restriction Fragment Length; D014412:Tumor Virus Infections / Q000473:pathology* / Q000821:virology; D014860:Warts / Q000473:pathology
D004279:DNA, Viral