title: Optimization of process parameters for the continuous ethanol production by Kluyveromyces lactis immobilized cells in hydrogel copolymer carrier.
abstract: In the present study the optimized parameters for highest ethanol productivity by Kluyveromyces lactis immobilized cells bioreactor were obtained using the method of Lagrange multipliers. Immobilized growing yeast cells in PVA: HEMA (7%: 10%, w/w) hydrogel copolymer carrier produced by radiation polymerization were used in a packed-bed column reactor for the continuous production of ethanol from lactose at different levels of concentrations (50, 100 and 150) gL(-1). The results indicate that volumetric ethanol productivity is influenced by substrate concentration and dilution rate. The highest value 7.17 gL(-1) h(-1) is obtained at higher lactose concentration (150 gL(-1)) in feed medium and 0.3 h(-1) dilution rate. The same results have been obtained through the application of "LINGO" software for mathematical optimization.
authors.affiliation: Egyptian Petroleum Research Institute, Nasr City, Cairo.
authors.forename: S F
authors.initials: SF
authors.lastname: Deriase
authors.forename: L M
authors.initials: LM
authors.lastname: Farahat
authors.forename: A I
authors.initials: AI
authors.lastname: El-Batal
mesh_terms: D018914:Cells, Immobilized; D000431:Ethanol / Q000378:metabolism*; D005285:Fermentation; D007218:Industrial Microbiology / Q000379:methods; D007716:Kluyveromyces / Q000378:metabolism*; D007785:Lactose / Q000378:metabolism*; D008962:Models, Theoretical
chemical_list: D000431:Ethanol; D007785:Lactose