Genetic analysis and mapping of biochemical markers in an F2 intercross of two inbred strains of the rabbit (Oryctolagus cuniculus).
A total of 40 biochemical and four immunological markers found to be polymorphic in the rabbit in previous studies were screened in the AX/JU and IIIVO/JU inbred strains. Although the strains are considered unrelated, only eight (biochemical) markers werefound to be polymorphic between the two strains. These eight markers were analyzed in an F2 intercross population. Linkage was found for Est-5 and C on chromosome 1 and for Es-1, Est-2, Est-4, Est-6 and HP on linkage group VI. Two polymorphic markers, Es-3 and Mhr-1 could not be linked to any of the other markers.
Korstanje
R
R
Department of Laboratory Animal Science, Faculty of Veterinary Medicine, Utrecht University, The Netherlands. r.korstanje@las.vet.uu.nl
den Bieman
M
M
Campos
R
R
Esteves
P J
PJ
Lankhorst
A E
AE
van der Loo
W
W
van Zutphen
L F
LF
van Lith
H A
HA
Ferrand
N
N
D000818:Animals; D017849:Animals, Inbred Strains; D015415:Biomarkers; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004592:Electrophoresis, Starch Gel; D004950:Esterases / Q000235:genetics* / Q000378:metabolism; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008297:Male; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D011817:Rabbits / Q000235:genetics*
D015415:Biomarkers; D005819:Genetic Markers; D004950:Esterases