title: Painless thyroiditis induced by the cessation of betamethasone.
abstract: We describe the first reported case of painless thyroiditis induced by an abrupt cessation of betamethasone. A 53-year-old woman experienced transient thyrotoxicosis after the abrupt cessation of celestamine, a mixture of betamethasone and chlorpheniramine. Since neither TSH receptor- nor thyroid stimulating-antibodies were negative, and thyroid scintigram did not show the thyroid gland, she was diagnosed as having painless thyroiditis. Fourteen months after the onset of thyrotoxicosis, serum TSH was detectable without hypothyroidism. We speculate that reduction in betamethasone may be one of the triggers of painless thyroiditis.
authors.affiliation: Internal Medicine, Japanese Red Cross-Nagasaki Atomic Bomb Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Morita
authors.forename: Y
authors.initials: Y
authors.lastname: Ueda
authors.forename: N
authors.initials: N
authors.lastname: Yokoyama
mesh_terms: D018926:Anti-Allergic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001623:Betamethasone / Q000008:administration & dosage* / Q000627:therapeutic use; D002744:Chlorpheniramine / Q000008:administration & dosage* / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy; D013966:Thyroiditis / Q000209:etiology*; D013997:Time Factors; D028761:Withholding Treatment
chemical_list: D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D004338:Drug Combinations; D005938:Glucocorticoids; D002744:Chlorpheniramine; D001623:Betamethasone