Serum antibody response to polysaccharides in children with recurrent respiratory tract infections.
We evaluated children (15-months old and older) with recurrent upper respiratory tract infections and normal levels of immunoglobulins in serum for specific polysaccharide immunodeficiency using an enzyme-linked immunosorbent assay method. Results showed that of 12 patients vaccinated with Act-HIB vaccine, one did not develop specific antibodies to Haemophilus influenzae type b, demonstrating that such immunodeficiency is present in Costa Rican children.
López-Yap
A
A
Laboratorio Clínico, Caja de Seguro Social de Panamá, San José, Costa Rica. alberto68@latinmail.com
Abdelnour
A
A
Lomonte
B
B
Porras
O
O
D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D002675:Child, Preschool; D003364:Costa Rica; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006192:Haemophilus Infections / Q000276:immunology*; D018073:Haemophilus Vaccines / Q000276:immunology; D019741:Haemophilus influenzae type b / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000276:immunology* / Q000382:microbiology
D000907:Antibodies, Bacterial; D018073:Haemophilus Vaccines; D011135:Polysaccharides, Bacterial