title: Antimicrobial resistance of strains of the Bacteroides fragilis group isolated from the intestinal tract of children and adults in Brazil.
abstract: The results of this study show that there is a high frequency of resistant species in the Bacteroides fragilis group in the intestinal tract of children and adults in Brazil. B. fragilis was not studied. Of the 73 strains examined, B. distasonis was the most resistant species to penicillin, cefoxitin, cefotaxime and clindamycin. High rates of multiresistance were found, most commonly to penicillin and clindamycin (18 of 36 strains). High levels of beta-lactamase production were detected in isolates showing high resistance to penicillin and multiresistance to the cephamycins, suggesting a widespread dissemination of such resistance.
authors.affiliation: Bloco I, Centro de Ciências da Saúde, Instituto de Microbiologia Prof. Paulo de Góes, Universidade Federal de Rio de Janeiro, Cidade Universitária, Ilha do Fundão, CEP, 21941-590, Rio de Janeiro, Brazil.
authors.forename: K E
authors.initials: KE
authors.lastname: Avelar
authors.forename: J M
authors.initials: JM
authors.lastname: Vieira
authors.forename: L C
authors.initials: LC
authors.lastname: Antunes
authors.forename: L A
authors.initials: LA
authors.lastname: Lobo
authors.forename: E N
authors.initials: EN
authors.lastname: Antunes
authors.forename: R M
authors.initials: RM
authors.lastname: Domingues
authors.forename: M C
authors.initials: MC
authors.lastname: Ferreira
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001439:Bacteroides / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification; D001441:Bacteroides fragilis / Q000187:drug effects* / Q000201:enzymology; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007223:Infant; D007422:Intestines / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases