Pulmonary sequelae after electron spinal irradiation.
We measured pulmonary function in 21 patients, after craniospinal irradiation with a posterior spinal electron beam. The median age at treatment was 7.5 years. Nine patients (43%) demonstrated abnormal pulmonary function tests, five with restrictive changes, one with isolated diminished diffusion capacity, and three with obstructive disease. These changes were mild and predominantly asymptomatic.
Endicott
T J
TJ
Department of Radiation Oncology, Torrance Memorial Medical Center, 3330 Lomita Boulevard, Torrance, CA 90505, USA.
Fisher
B J
BJ
Wong
E
E
Paterson
N A
NA
Gaspar
L E
LE
Bauman
M
M
D000293:Adolescent; D000328:Adult; D016543:Central Nervous System Neoplasms / Q000532:radiotherapy*; D002648:Child; D002675:Child, Preschool; D016371:Cranial Irradiation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000532:radiotherapy; D017564:Radiation Pneumonitis; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*; D012129:Respiratory Function Tests; D013131:Spine