title: Lack of prior antiretroviral therapy is associated with increased mortality among hospitalized patients with AIDS in São Paulo, Brazil,.
abstract: The death rate in adults with acquired immune deficiency syndrome (AIDS) at the Institute of Infectious Diseases "Emilio Ribas" in São Paulo City has decreased significantly from 29% in 1995 to 19.8% in 1999, and hospitalization time has been reduced by 4 days in the period from 1998 to 1999. Lack of antiretroviral treatment (ART) before hospitalization was associated with death during hospitalization (odds ratio [OR] = 3.8), and survival was associated with previous use of three or more antiretrovirals (OR = 0.15). Therefore, we recommend an aggressive campaign for human immunodeficiency virus (HIV) antibody screening among the at-risk populations in Brazil to assure that ART is provided when necessary.
authors.affiliation: Institute of Infectious Diseases Emílio Ribas, Research Institutes at the Health Secretariat, São Paulo, SP, Brazil. J31@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Casseb
authors.forename: G S
authors.initials: GS
authors.lastname: Orrico
authors.forename: R D
authors.initials: RD
authors.lastname: Feijo
authors.forename: L
authors.initials: L
authors.lastname: Guaracy
authors.forename: L A
authors.initials: LA
authors.lastname: Medeiros
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000401:mortality*; D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage; D001938:Brazil / Q000453:epidemiology; D016009:Chi-Square Distribution; D016001:Confidence Intervals; D005260:Female; D017052:Hospital Mortality; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D016017:Odds Ratio; D012307:Risk Factors; D014505:Urban Population
chemical_list: D019380:Anti-HIV Agents