Chemical synthesis of a P(k)-antigenic globotriose analogue with a functionalized aglycon.
6-Aminohexyl alpha-D-galactopyranosyl-(1-->4)-beta-D-galactopyranosyl-(1-->4)-beta-D-glucopyranoside (2), a globotriose analogue with a functionalized aglycon, was synthesized, using alpha-D-galactopyranosyluronic acid-(1-->4)-D-galactopyranosyluronic acid [di-GalA (3)] as the starting material, which is commercially available or can be readily prepared from pectin.
Liu
M Z
MZ
Department of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA.
Fan
H N
HN
Lee
Y C
YC
D002240:Carbohydrate Sequence; D002855:Chromatography, Thin Layer; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010368:Pectins; D014312:Trisaccharides / Q000138:chemical synthesis*
C442439:6-aminohexylgalactopyranosyl-(1-4)-galactopyranosyl-(1-4)-glucopyranoside; D014312:Trisaccharides; C113460:globotriose; D010368:Pectins