[Sarcoidosis and comorbidity: retrospective study of 32 cases].
OBJECTIVE
A retrospective study was set up to investigate active pathologic processes associated with sarcoidosis diagnosed in 32 patients.


METHODS
Eighteen patients had two identified granulomatous localizations (56%) and 14 patients had three localizations or more (27%). Comorbidity was noticed in nine patients (28% of cases). Sarcoidosis was associated with an infectious disease five times (hepatitis C virus [HCV] infection three times, including one case after recombinant interferon alpha therapy, and HIV and HCV co-infection two times). The association of sarcoidosis with a chronic immunologic inflammatory disease was noticed four times (lupus erythematosus two times, myasthenia and primary biliary cirrhosis). Finally, in two cases sarcoidosis was associated with a neoplasia (non-Hodgkin's lymphoma in a co-infected HIV-HCV patient, ovarian cystadenocarcinoma in another patient). Sarcoidosis preceded or revealed the comorbidity four times.
Bonnet
F
F
Fédération de médecine interne, maladies infectieuses et pathologie tropicale, hôpital Saint-André, 1, rue Jean-Burguet, 33075 Bordeaux, France. fabrice.bonnet@chu-bordeaux.fr
Dubuc
J
J
Morlat
P
P
Delbrel
X
X
Doutre
M S
MS
de Witte
S
S
Bernard
N
N
Lacoste
D
D
Longy-Boursier
M
M
Beylot
J
J
D000328:Adult; D000368:Aged; D015897:Comorbidity; D003536:Cystadenocarcinoma / Q000150:complications; D005260:Female; D015658:HIV Infections / Q000150:complications; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D007154:Immune System Diseases / Q000150:complications*; D008105:Liver Cirrhosis, Biliary / Q000150:complications; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications; D009369:Neoplasms / Q000150:complications*; D010051:Ovarian Neoplasms / Q000150:complications; D012107:Research Design; D012189:Retrospective Studies; D012307:Risk Factors; D012507:Sarcoidosis / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D014777:Virus Diseases / Q000150:complications*
Sarcoïdose et comorbidité: étude rétrospective de 32 observations.