Radical [3+2] annulation of N-allyl-N-chlorotosylamide with alkenes via atom-transfer process.
[reaction: see text]. A radical [3+2] annulation reaction with an N-centered radical has been developed. The reaction of alkenes with N-allyl-N-chlorotosylamide yields the corresponding pyrrolidine derivatives in good yields in the presence of Et3B as a radical initiator.
Tsuritani
T
T
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 606-8501, Japan.
Shinokubo
H
H
Oshima
K
K