[Effects of korinfar-retard on parameters for the left ventricular diastolic function in patients with hypertensive disease].
Enrolled in the study were 52 patients with stage II-III disordered relaxation type diastolic dysfunction of the left ventricle and that of the restrictive type. All patients underwent echocardiography and doppleroechocardiography before and after having been placed on corinfarretard, 10 to 20 mg daily. The duration of the course of treatment was in the average 19.4 +/- 1.51 days. There was an improvement in patients on the above treatment on parameters associated with the temporal patterns of the diastole, those patients with disturbed relaxation type dysfunction having derived the greatest benefit from it. In patients with restrictive type diastolic dysfunction of the left ventricle, no significant changes were revealed in the diastole related to the drug in question.
Sydorova
N Iu
NIu
Sierkova
V K
VK
Monastyrskyĭ
Iu I
IuI
Sheverda
N V
NV
D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003692:Delayed-Action Preparations; D003971:Diastole; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D018608:Ultrasonography, Doppler; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*
D000889:Anti-Arrhythmia Agents; D002121:Calcium Channel Blockers; D003692:Delayed-Action Preparations; D009543:Nifedipine
Vplyv Korynfaru-Retard na parametry diastolichnoï funktsiï livoho shlunochka u khvorykh na hipertonichnu khvorobu.