Increasing body fat mass in the first year of hemodialysis.
Nutritional status affects well-being and survival in patients who are undergoing hemodialysis. It was examined how maintenance hemodialysis altered body fat mass. In 72 patients with chronic renal failure (age, 62 +/- 12 yr; 42 men, 30 women), body fat was measured by dual x-ray absorptiometry 1 mo after initiation of maintenance hemodialysis and approximately 1 yr later (mean +/- SD, 11 +/- 2 mo). The second measurement showed significantly greater body fat mass than the first (11.38 +/- 3.84 versus 10.09 +/- 4.12 kg; P < 0.0001). After calculation of the change in body fat mass per month, no significant differences were evident in relation to gender or to presence of diabetes. Changes in body fat mass per month correlated negatively with baseline serum albumin concentration (r = -0.449, P < 0.0001) and baseline body fat mass (r = -0.423, P < 0.001). These factors independently influenced the change according to multiple regression analysis (R(2) = 0.323, P < 0.0001). In conclusion, body fat mass increases significantly in the first year of maintenance hemodialysis, especially in patients with poor nutritional status. More general, dual x-ray absorptiometry assessment of body fat mass was found to be useful for evaluating the nutritional status of hemodialysis patients.
Ishimura
Eiji
E
Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan.
Okuno
Senji
S
Shirasagi Hospital Kidney Center, Osaka, Japan.
Kim
Masao
M
Shirasagi Hospital Kidney Center, Osaka, Japan.
Yamamoto
Tadashi
T
Shirasagi Hospital Kidney Center, Osaka, Japan.
Izumotani
Tsuyoshi
T
Shirasagi Hospital Kidney Center, Osaka, Japan.
Otoshi
Tatsuyuki
T
Shirasagi Hospital Kidney Center, Osaka, Japan.
Shoji
Tetsuo
T
Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan.
Inaba
Masaaki
M
Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan.
Nishizawa
Yoshiki
Y
Second Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan.
D015502:Absorptiometry, Photon; D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000368:Aged; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D009929:Organ Size; D006435:Renal Dialysis; D013851:Thinness; D013997:Time Factors