[Dependence of immune and biochemical homeostasis mechanisms on lead accumulation in the body (experimental study)].
It was established in experiments on rats that lead accumulation in organism caused by 1/100 DL50 lead acetate repeated injections connected with Ca2+ competition forcing out from bone tissue and taking it out from blood. It was accompanied by homeostasis maintenance physiologic mechanisms disturbance and lead toxic influence realization in liver, cordial, brain tissues, as well as immune toxic influence display on neutrophiles, periphery blood lymphocytes and on spleen lymphocytes.
Kundiev
Iu I
IuI
Stezhka
V A
VA
Dmitrukha
N N
NN
Lampeka
E G
EG
Didenko
M N
MN
Pokrovskaia
T N
TN
Onikienko
F A
FA
Blakita
I V
IV
Bil'ko
T A
TA
Mel'nik
Iu P
IuP
Padakina
E V
EV
D000818:Animals; D015415:Biomarkers; D002118:Calcium / Q000097:blood; D006706:Homeostasis / Q000502:physiology*; D007107:Immune System / Q000276:immunology*; D007854:Lead / Q000097:blood; D007855:Lead Poisoning / Q000097:blood* / Q000276:immunology*; D008297:Male
D015415:Biomarkers; D007854:Lead; D002118:Calcium
Zavisimost' izmeneniia immunnykh i biokhimicheskikh mekhanizmov podderzhaniia gomeostaza ot material'noĭ kumuliatsii svintsa v organizme (éksperimental'noe issledovanie).