[Components of the intracellular cyclic AMP system maintaining olfactory reception of amyl alcohol].
In experiments on isolated olfactory epithelium, cAMP was shown to have an intracellular signal system which participates in pentanol olfaction transduction. Increase in the intracellular cAMP level is associated with adenylate cyclase activation due to G-protein stimulation by odorant coupled with it.
Bigdaĭ
E V
EV
I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.
Samoĭlov
V O
VO
D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D000242:Cyclic AMP / Q000502:physiology*; D004789:Enzyme Activation; D006801:Humans; D008856:Microscopy, Fluorescence; D009812:Odorants; D009831:Olfactory Mucosa / Q000378:metabolism* / Q000648:ultrastructure; D000439:Pentanols / Q000494:pharmacology*; D011896:Rana temporaria; D015398:Signal Transduction; D012903:Smell
D000439:Pentanols; D000242:Cyclic AMP; D000262:Adenylyl Cyclases
Komponenty vnutrikletochnoĭ sistemy tsAMP, obespechivaiushchie oboniatel'nuiu retseptsiiu amilovogo spirta.