[Dynamics of the personality profile and cognitive functions in finlepsin treatment of partial epilepsy].
The aim of modern antiepileptic therapy is not only to decrease frequency of the seizures and to prevent their rise, but to decrease negative consequences of the treatment too. It is, first of all, to decrease the influence of the antiepileptic preparations on the cognitive functions and, therefore, on quality of the patients' life. During therapy of 40 patients (8-57 year-olds) with partial epilepsy the severity of the seizures as well as emotional and cognitive functions of the patients were evaluated. A significant decrease of the severity of the seizures was observed during therapy with finlepsin-retard (p < 0.002). These changes correlated both with a decrease of anxiety according to MMPI questionnaire (p < 0.0001) and with an increase of the volume of the short-term imaginary memory. Finlepsin-retard is effective therapy for epilepsy.
Karlov
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VA
Andreeva
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OV
D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D001921:Brain / Q000503:physiopathology; D002220:Carbamazepine / Q000627:therapeutic use*; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D003692:Delayed-Action Preparations / Q000627:therapeutic use; D004828:Epilepsies, Partial / Q000150:complications* / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008950:MMPI; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010554:Personality Disorders / Q000175:diagnosis / Q000209:etiology*; D012720:Severity of Illness Index
D000927:Anticonvulsants; D003692:Delayed-Action Preparations; D002220:Carbamazepine
Dinamika profilia lichnosti i kognitivnykh funktsiĭ pri lechenii partsial'noĭ épilepsii finlepsinom.