[Effects of basic therapy of ischemic heart disease on vascular-platelet hemostasis during myocardial revascularization].
Effects of preoperative therapy of coronary diseases with calcium antagonists and aspirin on vascular platelet hemostasis during aortocoronary shunting (ACS) have been studied in order to evaluate the role of hemostasis disorders in the pathogenesis of perioperative hemorrhagic complications. Therapy of coronary disease with these drugs during preparation to ACS can involve changes in platelet functional activity, depending on the individual sensitivity of patients. Drug-induced thrombocytopathy can induce pathological hemorrhages in the perioperative period of ACS.
Vorob'eva
N A
NA
Nedashkovskiĭ
E V
EV
D000328:Adult; D000368:Aged; D001241:Aspirin / Q000494:pharmacology* / Q000627:therapeutic use; D001792:Blood Platelets / Q000187:drug effects*; D002121:Calcium Channel Blockers / Q000494:pharmacology* / Q000627:therapeutic use; D001026:Coronary Artery Bypass; D003627:Data Interpretation, Statistical; D005260:Female; D005343:Fibrinolytic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006487:Hemostasis / Q000187:drug effects*; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000601:surgery; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D011300:Preoperative Care
D002121:Calcium Channel Blockers; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D001241:Aspirin
Vliianie bazisnoĭ terapii IBS na sostoianie sosudisto-trombotsitarnogo gemostaza pri operatsii revaskuliarizatsii miokarda.