[Features of neurotransmitter pool in cerebrospinal fluid of patients with epilepsy].
The paper deals with the state of neurotransmitter pool in cerebrospinal fluid of epileptic patients. There were significant peculiarities of the dynamics of both excitatory (glutamate, aspartate) and inhibitory (GABA, glycine, taurine) neurotransmitters in respect of the severity of the pathologic process, frequency and type of convulsive seizures. The correlation found between a degree of the disease severity and a level of glutamate in cerebrospinal fluid after the seizures and between them could be a criterion for the prognosis of epilepsy.
Raevskiĭ
K S
KS
Avakian
G N
GN
Kudrin
V S
VS
Nesterova
S I
SI
Gusev
E I
EI
D000328:Adult; D001224:Aspartic Acid / Q000134:cerebrospinal fluid; D001921:Brain / Q000378:metabolism / Q000503:physiopathology; D004827:Epilepsy / Q000134:cerebrospinal fluid* / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D018698:Glutamic Acid / Q000134:cerebrospinal fluid; D005998:Glycine / Q000134:cerebrospinal fluid; D006801:Humans; D008297:Male; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000134:cerebrospinal fluid*; D012720:Severity of Illness Index; D013654:Taurine / Q000134:cerebrospinal fluid; D005680:gamma-Aminobutyric Acid / Q000134:cerebrospinal fluid
D018377:Neurotransmitter Agents; D013654:Taurine; D001224:Aspartic Acid; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D005998:Glycine
Osobennosti neĭrotransmitternogo pula v spinnomozgovoĭ zhidkosti bol'nykh épilepsieĭ.