Identification, determination, and biological evaluation of a novel styrene trimer contained in polystyrene food containers. 2.
An unidentified styrene trimer (ST) isolated from the acetonitrile extract of polystyrene (PS) food containers was characterized as (1S*,6R*,7S*,8S*,11R*)-6,11-diphenyltricyclo[6,2,2,0(2,7)]dodeca-2,9-diene. The content and migration of this compound in PS food containers were determined by GC-MS (SIM). Furthermore, an endocrine-disrupting effect was tested using in vitro and in vivo assays of the compound. In conclusion, it seems that the compound does not present the effect.
Hirano
S
S
Central Research Institute, Nissin Food Products Company, Ltd., 2247 Noji, Kusatsu, Shiga 525-0055, Japan. s-hirano@mb1.nissin.foods.co.jp
Tanaka
M
M
Date
K
K
Ohno
K
K
Kobayashi
K
K
Sakurai
T
T
Nagao
Y
Y
Nobuhara
Y
Y
Yamada
T
T
D000818:Animals; D018857:Food Packaging; D008401:Gas Chromatography-Mass Spectrometry; D011137:Polystyrenes / Q000032:analysis* / Q000633:toxicity; D051381:Rats; D013343:Styrenes / Q000032:analysis* / Q000633:toxicity
D011137:Polystyrenes; D013343:Styrenes