[Induction of posterior detachment of the vitreous body by intraoperative vitreo-syneresis with injection of water-soluble polymers (an experimental-morphological study)].
The capacity of water-soluble polymers (polyethylenimine, polyvinylpyrrolidone with copolymers) to induce posterior detachment of the vitreous by its rapid condensation (vitreosynerysis) was studied in experiments on 14 rabbits. Histological studies showed that water-soluble polymers specifically react forming complexes with components of the vitreous. The vitreous shrinks under the effect of polyelectrolytes (vitreosynerysis), which leads to its posterior detachment 1.5 h after injection of the polymer into the vitreous cavity: complete detachment was attained in 2 animals and partial in 8. The degree of vitreosynerysis depends on the complex-forming activity of polyelectrolytes towards the vitreous components. Polymers used in our study exerted no toxic or traction effects on the adjacent structures of the eye.
Skvorchenko
D O
DO
Khoroshilova-Maslova
I P
IP
Andreeva
L D
LD
Sharafetdinov
I Kh
IKh
Shtil'man
M I
MI
Maklakova
I A
IA
Uzunian
D G
DG
D000818:Animals; D010592:Pharmaceutic Aids / Q000008:administration & dosage; D010952:Plasma Substitutes / Q000008:administration & dosage; D020959:Polyethylene / Q000008:administration & dosage; D011108:Polymers / Q000008:administration & dosage*; D011205:Povidone / Q000008:administration & dosage; D011817:Rabbits; D013997:Time Factors; D014463:Ultrasonography; D014822:Vitreous Body / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D020255:Vitreous Detachment
D010592:Pharmaceutic Aids; D010952:Plasma Substitutes; D011108:Polymers; D020959:Polyethylene; D011205:Povidone
Induktsiia zadneĭ otsloĭki steklovidnogo tela putem intraoperatsionnogo vitreosinerezisa pri vvedenii vodorastvorimykh polimerov (éksperimental'no-morfologicheskoe issledovanie).