Treatment of childhood phimosis with a moderately potent topical steroid.
BACKGROUND
Recently, topical steroid application has been shown by a small number of studies to be an effective alternative to circumcision for the treatment of phimosis. However, only potent or very potent corticosteroids have been more thoroughly studied in this treatment option. A prospective study was conducted to determine whether comparable results could be achieved using a weaker steroid cream.


METHODS
Boys, 3-13 years of age, with non-retractable foreskin due to a tight ring at the tip were offered the regimen of twice-daily preputial retraction and topical application of 0.02% triamcinolone acetonide cream. The degree of preputial retractability was assessed at presentation and at 4 and 6 weeks of treatment. Success was defined as full retraction or free retraction up to agglutination of the foreskin to the glans.


RESULTS
Eighty-three boys completed the treatment. Successful retraction was achieved in 48/83 (58%) patients after 4 weeks and 70/83 (84%) patients after 6 weeks of application. The overall response rate aggregated from six published series using 0.05% betamethasone was 87% at 4 weeks and 90% on completion of treatment. Thus, the results appear inferior when analysed at 4 weeks but compare favourably with those reported for a more potent steroid on completion of the full course of treatment.


CONCLUSIONS
Even though the triamcinolone cream used in the present study is less potent than the more commonly used 0.05% betamethasone valerate cream, it could effect comparable improvements in foreskin retractability after 6 weeks of treatment.
Ng
W T
WT
Department of Surgery, Yan Chai Hospital, Tsuen Wan, Hong Kong. houston_n@yahoo.com
Fan
N
N
Wong
C K
CK
Leung
S L
SL
Yuen
K S
KS
Sze
Y S
YS
Cheng
P W
PW
D000287:Administration, Topical; D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008297:Male; D009824:Ointments / Q000008:administration & dosage / Q000627:therapeutic use; D010413:Penis / Q000187:drug effects*; D010688:Phimosis / Q000188:drug therapy*; D011446:Prospective Studies; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage* / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D009824:Ointments; D014222:Triamcinolone Acetonide