[Some aspects of the formation of the immune system organs in newborn rats born to females with chronic hepatitis].
The immune system organs formation and development was studied in 61 rat younglings born to pregnant animals with chronic toxic hepatitis. A comparative investigation permitted ascertaining that chronic heliotrine hepatitis in female rats results in an increased death rate in the progeny, the highest mortality being recordable at day 1 to 3 after birth. The surviving live younglings reveal against the background of thymus hypoplasia a significant inhibition of processes of formation of the peripheral immune organs lymphoid tissue.
Azizova
F Kh
FKh
Tukhfatullin
F F
FF
Tursunmetov
I R
IR
Tukhtaev
K R
KR
D000818:Animals; D000831:Animals, Newborn; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications*; D002908:Chronic Disease; D005260:Female; D007107:Immune System / Q000254:growth & development / Q000276:immunology* / Q000473:pathology; D007109:Immunity; D007153:Immunologic Deficiency Syndromes / Q000209:etiology / Q000276:immunology*; D008221:Lymphoid Tissue / Q000254:growth & development / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications; D051381:Rats; D015996:Survival Rate; D013950:Thymus Gland / Q000254:growth & development / Q000473:pathology
Osobennosti stanovleniia organov immunnoĭ sistemy u krysiat, rozhdennykh ot samok s khronicheskim toksicheskim gepatitom.