Levodopa responsive Parkinsonism in adults with Angelman Syndrome.
Two intellectually disabled adults with Angelman Syndrome are reported who developed intermittent episodes of a severe resting tremor, cogwheel rigidity and bradykinesia in their late teens. The Parkinsonism was not due to medications and there was a dramatic improvement with levodopa therapy. The association between Angelman Syndrome and Parkinsonism has not previously been described.
Harbord
M
M
Department of Paediatrics and Child Health, Flinders Medical Centre, Bedford Park, SA, Australia.
D000328:Adult; D017204:Angelman Syndrome / Q000188:drug therapy*; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D020734:Parkinsonian Disorders / Q000188:drug therapy*
D000978:Antiparkinson Agents; D007980:Levodopa