Nucleotide polymorphism in microcin V plasmids.
DNA sequence polymorphism was determined for the microcin V gene cluster encoded on the microcin V plasmids of 12 natural isolates of Escherichia coli. These microcin V gene clusters are similar in DNA sequence, with only 10 of the 683 bp polymorphic. Further, the levels and patterns of microcin V gene cluster polymorphism differ from those of a chromosomal region, trpORF2, sequenced from each of the host isolates. These contrasting levels and patterns of polymorphism suggest that the microcin V gene cluster has experienced an evolutionary history different from that of the host.
Pinou
T
T
Department of Ecology and Evolution, Yale University, New Haven, Connecticut 06520, USA.
Riley
M A
MA
D001430:Bacteriocins / Q000235:genetics*; D004269:DNA, Bacterial; D004926:Escherichia coli / Q000235:genetics*; D004927:Escherichia coli Infections / Q000382:microbiology; D006801:Humans; D010957:Plasmids; D011110:Polymorphism, Genetic
D001430:Bacteriocins; D004269:DNA, Bacterial; C020411:microcin