title: Significant role of interleukin-8 in pathogenesis of pulmonary disease due to Mycoplasma pneumoniae infection.
abstract: We found elevated levels of interleukin-8 in pleural fluid samples from patients with pleural effusion and with a sustained fibrotic change of the lung due to Mycoplasma pneumoniae infection. This result suggests a critical role of interleukin-8 in the pathogenesis of a certain type of pulmonary disease caused by M. pneumoniae.
authors.affiliation: Department of Pediatrics, Sapporo Tetsudo (JR) Hospital, N3 E1 Chuo-ku, Sapporo 060-0033, Japan. naritamy@d5.dion.ne.jp
authors.forename: M
authors.initials: M
authors.lastname: Narita
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Yamada
authors.forename: S
authors.initials: S
authors.lastname: Abe
authors.forename: T
authors.initials: T
authors.lastname: Ariga
authors.forename: Y
authors.initials: Y
authors.lastname: Sakiyama
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D016209:Interleukin-8 / Q000097:blood / Q000502:physiology*; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D011019:Pneumonia, Mycoplasma / Q000276:immunology* / Q000382:microbiology*; D016212:Transforming Growth Factor beta / Q000097:blood; D053773:Transforming Growth Factor beta1
chemical_list: D016209:Interleukin-8; C508960:TGFB1 protein, human; D016212:Transforming Growth Factor beta; D053773:Transforming Growth Factor beta1