title: [Parkinson's disease].
abstract: Depression is a most common psychiatric complication of Parkinson's patients. Approximately 30% of Parkinson's patients show depressive mood changes. Loss of interest, feelings of hopelessness, marked loss of energy and psychomotor retardation are common depressive symptoms with parkinsonism. Suicidal ideations and delusions are less frequent in Parkinson's patients with depression in compared to endogenous depression. Somatic symptoms, like fatigue, constipation, headache, insomnia, loss of appetite, dizzinees and sweating are usually seen in Parkinson's patient with depression. Serotonin reuptake inhibitors and selegiline are recommended for the treatment of depression in parkinsonian patients.
authors.affiliation: Hyogo Institute for Aging Brain & Cognitive Disorders.
authors.forename: K
authors.initials: K
authors.lastname: Miyoshi
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use; D003863:Depression / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D012642:Selegiline / Q000627:therapeutic use; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa; D008996:Monoamine Oxidase Inhibitors; D012642:Selegiline; D017367:Selective Serotonin Reuptake Inhibitors