Cell cycle: connecting DNA replication to sporulation in Bacillus.
Checkpoints have been a staple of eukaryotic cell cycle research for the past decade, but little is known about checkpoints in prokaryotes. New work on sporulation in Bacillus fills that gap by showing that such control systems function to coordinate aspects of the bacterial cell cycle.
Michael
W M
WM
Molecular & Cellular Biology, The Biological Laboratories, Harvard University, Cambridge, Massachusetts 02138, USA. matt@mcb.harvard.edu
D001412:Bacillus subtilis / Q000502:physiology*; D001426:Bacterial Proteins / Q000378:metabolism; D002453:Cell Cycle / Q000502:physiology*; D004261:DNA Replication / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D008957:Models, Genetic; D013171:Spores, Bacterial
D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; C066312:DnaA protein, Bacteria; C422745:suppressor of DnaA, Bacillus subtilis