title: [Aneurysm of the V. magna cerebri (vein of Galen), a cause of congestive heart failure in five neonates].
abstract: In five neonates (4 girls and 1 boy) with aneurysm of the V. magna cerebri, clinical signs of congestive heart failure were encountered. In three of the neonates the symptoms were detected postnatally and in two prenatally. In one of the prenatally detected cases the aneurysm was treated by embolisation during the first week of life. Upon follow-up at six years of age, this patient's situation was stable but hydrocephalus had led to poor visuomotor development, mild motor retardation and mental retardation. In the other infants, medicinal treatment of the congestive heart failure was discontinued in view of ischaemic brain damage, and these patients subsequently died. Congestive heart failure often develops in neonates with an aneurysm of the V. magna cerebri due to low cerebrovascular resistance. A continuous murmur over the skull is pathognomonic for this condition.
authors.affiliation: Afd. Kindercardiologie, Universitair Medisch Centrum, locatie Wilhelmina Kinderziekenhuis, Postbus 85090, 3508 AB Utrecht.
authors.forename: H L
authors.initials: HL
authors.lastname: van Westreenen
authors.forename: L S
authors.initials: LS
authors.lastname: de Vries
authors.forename: R H
authors.initials: RH
authors.lastname: Gooskens
authors.forename: P G
authors.initials: PG
authors.lastname: Nikkels
authors.forename: P
authors.initials: P
authors.lastname: Stoutenbeek
authors.forename: E J
authors.initials: EJ
authors.lastname: Meijboom
mesh_terms: D002550:Cerebral Veins; D004621:Embolization, Therapeutic; D017809:Fatal Outcome; D005260:Female; D006333:Heart Failure / Q000209:etiology*; D006801:Humans; D006849:Hydrocephalus / Q000150:complications* / Q000209:etiology; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis*; D002532:Intracranial Aneurysm / Q000150:complications* / Q000000981:diagnostic imaging; D007969:Leukomalacia, Periventricular / Q000209:etiology; D008297:Male; D011247:Pregnancy; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal
vernacular_title: Aneurysma van de V. magna cerebri (Galeni); oorzaak van decompensatio cordis bij 5 pasgeborenen.