title: The Italian version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ).
abstract: We report herein the results of the cross-cultural adaptation and validation into the Italian language of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthritis (JIA). The Child Health Questionnaire (CHQ) is a generic health instrument designed to capture the physical and psychosocial well-being of children independently from the underlying disease. The Italian CHAQ was already published in the literature and was therefore revalidated while the Italian CHQ was fully cross culturally adapted with 3 forward and 3 backward translations, and than validated. A total of 1,192 subjects were enrolled: 404 patients with JIA (16% systemic onset, 31% polyarticular onset, 21% extended oligoarticular subtype, and 32% persistent oligoarticular subtype) and 788 healthy children. The CHAQ clinically discriminated between healthy subjects and JIA patients, with the systemic, polyarticular and extended oligoarticular subtypes having a higher degree of disability, pain, and a lower overall well-being when compared to their healthy peers. Also the CHQ clinically discriminated between healthy subjects and JIA patients, with the systemic onset, polyarticular onset and extended oligoarticular subtypes having a lower physical and psychosocial well-being when compared to their healthy peers. In conclusion the Italian version of the CHAQ-CHQ are reliable, and valid tools for the functional, physical and psychosocial assessment of children with JIA.
authors.affiliation: Laboratorio di Informatica Medica, IRCCS S. Matteo, Università di Pavia, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Ruperto
authors.forename: A
authors.initials: A
authors.lastname: Ravelli
authors.forename: A
authors.initials: A
authors.lastname: Pistorio
authors.forename: C
authors.initials: C
authors.lastname: Malattia
authors.forename: S
authors.initials: S
authors.lastname: Viola
authors.forename: S
authors.initials: S
authors.lastname: Cavuto
authors.forename: M
authors.initials: M
authors.lastname: Alessio
authors.forename: M G
authors.initials: MG
authors.lastname: Alpigiani
authors.forename: A
authors.initials: A
authors.lastname: Buoncompagni
authors.forename: F
authors.initials: F
authors.lastname: Corona
authors.forename: E
authors.initials: E
authors.lastname: Cortis
authors.forename: F
authors.initials: F
authors.lastname: Falcini
authors.forename: V
authors.initials: V
authors.lastname: Gerloni
authors.forename: L
authors.initials: L
authors.lastname: Lepore
authors.forename: M L
authors.initials: ML
authors.lastname: Sardella
authors.forename: C G
authors.initials: CG
authors.lastname: Strano
authors.forename: F
authors.initials: F
authors.lastname: Zulian
authors.forename: L
authors.initials: L
authors.lastname: Gado-West
authors.forename: A
authors.initials: A
authors.lastname: Tortorelli
authors.forename: F
authors.initials: F
authors.lastname: Fantini
authors.forename: A
authors.initials: A
authors.lastname: Martini
mesh_terms: D000293:Adolescent; D001171:Arthritis, Juvenile / Q000175:diagnosis*; D002648:Child; D003431:Cross-Cultural Comparison; D003466:Cultural Characteristics; D004185:Disability Evaluation; D005260:Female; D006304:Health Status; D006801:Humans; D007558:Italy; D007802:Language; D008297:Male; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires