title: New indole alkaloids from the bark of Nauclea orientalis.
abstract: Four new alkaloids, nauclealines A (1) and B (2) and naucleosides A (3) and B (4), together with six known compounds, strictosamide (5), vincosamide (6), pumiloside (7), kelampayoside A, sitosterol, and sitosteryl beta-D-glucoside, were isolated from the bark of Nauclea orientalis. The structures of 1-4 were elucidated using 1D and 2D NMR spectral methods, including COSY, DEPT, HMQC, (13)C-(1)H HMBC, and (15)N-(1)H HMBC.
authors.affiliation: National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, Mississippi 38677, USA.
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
authors.forename: H N
authors.initials: HN
authors.lastname: ElSohly
authors.forename: M R
authors.initials: MR
authors.lastname: Jacob
authors.forename: D S
authors.initials: DS
authors.lastname: Pasco
authors.forename: L A
authors.initials: LA
authors.lastname: Walker
authors.forename: A M
authors.initials: AM
authors.lastname: Clark
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D002855:Chromatography, Thin Layer; D007211:Indoles / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010219:Papua New Guinea; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D019666:Rubiaceae / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000470:Alkaloids; D007211:Indoles