KCB-328 (C&C Research Labs).
C & C Research Labs is investigating the class III antiarrhythmic KCB-328 as a potential treatment for heart arrhythmia [310688]. The compound is potent in vitro, with little reverse frequency-dependence when compared with E-4031 (qv) and dofetilide (qv) [223384]. KCB-328 is in preclinical development [351687].
Billman
G
G
Ohio State University, Columbus 43210, USA. billman.1@pop.service.ohio-state.edu
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D006801:Humans; D010627:Phenethylamines / Q000494:pharmacology*; D013449:Sulfonamides / Q000494:pharmacology*
C112304:1-(2-amino-4-methanesulfonamidophenoxy)-2-(N-(3,4-dimethoxyphenethyl)-N-methylamino)ethane; D000889:Anti-Arrhythmia Agents; D010627:Phenethylamines; D013449:Sulfonamides