title: Identification, determination, and biological evaluation of a novel styrene trimer contained in polystyrene food containers. 2.
abstract: An unidentified styrene trimer (ST) isolated from the acetonitrile extract of polystyrene (PS) food containers was characterized as (1S*,6R*,7S*,8S*,11R*)-6,11-diphenyltricyclo[6,2,2,0(2,7)]dodeca-2,9-diene. The content and migration of this compound in PS food containers were determined by GC-MS (SIM). Furthermore, an endocrine-disrupting effect was tested using in vitro and in vivo assays of the compound. In conclusion, it seems that the compound does not present the effect.
authors.affiliation: Central Research Institute, Nissin Food Products Company, Ltd., 2247 Noji, Kusatsu, Shiga 525-0055, Japan. s-hirano@mb1.nissin.foods.co.jp
authors.forename: S
authors.initials: S
authors.lastname: Hirano
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Date
authors.forename: K
authors.initials: K
authors.lastname: Ohno
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Sakurai
authors.forename: Y
authors.initials: Y
authors.lastname: Nagao
authors.forename: Y
authors.initials: Y
authors.lastname: Nobuhara
authors.forename: T
authors.initials: T
authors.lastname: Yamada
mesh_terms: D000818:Animals; D018857:Food Packaging; D008401:Gas Chromatography-Mass Spectrometry; D011137:Polystyrenes / Q000032:analysis* / Q000633:toxicity; D051381:Rats; D013343:Styrenes / Q000032:analysis* / Q000633:toxicity
chemical_list: D011137:Polystyrenes; D013343:Styrenes