title: Paradoxical vestibular disease with trigeminal nerve-sheath tumor in a dog.
abstract: A thirteen-year old spayed female poodle was referred because of atrophy of temporal and masseter muscles on the left and head tilt and episodical circling to the right side. Additionally, decreased facial sensation, absent menace reaction, palpebral and corneal reflexes on the left side, as well as ipsilateral hemiparesis and tongue palsy were noticed. Generalised vestibular ataxia and hypermetria in the front limbs were present. Based on the clinical signs, the presumptive anatomical localization of the lesion was the cerebellopontine angle including parts of the caudal brainstem with involvement of the trigeminal, facial and hypoglossal nerves. Involvement of either flocculonodular lobe or the caudal cerebellar peduncle on the left side causing paradoxical vestibular disease was suspected. On magnetic resonance imaging a large enhancing lesion in the area of the left cerebellopontine angle involving the trigeminal nerve and compressing cerebellum and brainstem was seen. Because of the poor prognosis the dog was euthanized on the owner's request. This space occupying lesion could be identified as a trigeminal neurofibrosarcoma/schwannoma on post mortem histopathological examination.
authors.affiliation: Department of Clinical Veterinary Medicine, Small Animal Section, University of Bern, Germany. sigitas.cizinauskas@itn.unibe.ch
authors.forename: S
authors.initials: S
authors.lastname: Cizinauskas
authors.forename: J
authors.initials: J
authors.lastname: Lang
authors.forename: R
authors.initials: R
authors.lastname: Maier
authors.forename: R
authors.initials: R
authors.lastname: Fatzer
authors.forename: A
authors.initials: A
authors.lastname: Jaggy
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D003390:Cranial Nerve Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008279:Magnetic Resonance Imaging; D009442:Neurilemmoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D018319:Neurofibrosarcoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D011379:Prognosis; D020433:Trigeminal Nerve Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D015837:Vestibular Diseases / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*