title: Excretory-secretory antigens of Trypanosoma cruzi are potentially useful for serodiagnosis of chronic Chagas' disease.
abstract: The reactivities of sera from chronic chagasic patients against the trypomastigote excreted-secreted antigens (TESA) of Trypanosoma cruzi strains with different biodemes were analyzed by TESA-blot and TESA-enzyme-linked immunosorbent assay (ELISA). Although both tests presented high sensitivity and specificity, TESA-ELISA is more appropriate for screening a larger number of samples.
authors.affiliation: Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhães/FIOCRUZ, Hospital Universitário Oswaldo Cruz/UPE, CEP 50670-420 Recife-PE, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Nakazawa
authors.forename: D S
authors.initials: DS
authors.lastname: Rosa
authors.forename: V R
authors.initials: VR
authors.lastname: Pereira
authors.forename: M O
authors.initials: MO
authors.lastname: Moura
authors.forename: V C
authors.initials: VC
authors.lastname: Furtado
authors.forename: W V
authors.initials: WV
authors.lastname: Souza
authors.forename: M N
authors.initials: MN
authors.lastname: Barros
authors.forename: F G
authors.initials: FG
authors.lastname: Abath
authors.forename: Y M
authors.initials: YM
authors.lastname: Gomes
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000097:blood*; D014355:Chagas Disease / Q000175:diagnosis* / Q000469:parasitology*; D002908:Chronic Disease; D004797:Enzyme-Linked Immunosorbent Assay; D006168:Guinea Pigs; D006801:Humans; D015151:Immunoblotting; D012698:Serologic Tests; D014349:Trypanosoma cruzi / Q000276:immunology*
chemical_list: D000953:Antigens, Protozoan