title: Choroidal neovascularization associated with aplasia of the optic nerve.
abstract: OBJECTIVE
  To report an unusual case of unilateral aplasia of the optic nerve associated with choroidal neovascularization.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  In a 29-year-old female with optic nerve aplasia of the right eye and no choroidal neovascularization at age 23 years, choroidal neovascularization of the right eye was present by ophthalmoscopy and fluorescein angiography.
  
  
  RESULTS
  Fluorescein angiography disclosed de novo choroidal neovascularization corresponding to fibrovascular proliferation evident on ophthalmoscopy at age 29 years.
  
  
  CONCLUSIONS
  Choroidal neovascularization may develop de novo during adult life in an eye with optic nerve aplasia.
authors.affiliation: Wilmer Ophthalmological Institute, The Johns Hopkins Hospital, 600 North Wolfe St., Baltimore, MD 21287, USA. dpieramici@jhmi.edu
authors.forename: D J
authors.initials: DJ
authors.lastname: Pieramici
authors.forename: C
authors.initials: C
authors.lastname: Gonzalez
authors.forename: S C
authors.initials: SC
authors.lastname: Raja
mesh_terms: D000328:Adult; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000209:etiology*; D005124:Eye Abnormalities / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D009887:Ophthalmoscopy; D009900:Optic Nerve / Q000002:abnormalities* / Q000473:pathology; D014792:Visual Acuity