[ A long-term changes of macro- and microelement balance in blood serum, its ultrafiltrates and hairs after exposure to low doses of ionizing radiation].
Using inductively coupled plasma atomic emission spectrometry, we examined the level of Al, Cd, Co, Cu, Fe, Mg, Mo, P, Pb, S, and Zn in blood serum, its ultrafiltrates, and hairs of liquidators of the Chernobyl Nuclear Power Plant accident who were working in the disaster region in 1986-1987. Studies continued over a period of time provided evidence for a distinct change in the balance of macroelements and trace elements in the studied biological substrates of irradiated individuals. An increase in the level of copper in the ultrafiltrate and a marked decrease in the content of zinc in the ultrafiltrate are viewed as key factors in the generation of a response to low doses of ionizing radiation. Concerning the content of iron in hairs, we demonstrate its accelerated removal from the body of liquidators. The altered balance of biotic macroelements, phosphorus, and sulfur remained unchanged when these characteristics were studied as a function of time. We found changes in the ratios of divalent cations, magnesium and zinc, in the ultrafiltrates. The magnesium concentration in the studied biological substrates was the most stable characteristic after irradiation. The level of toxic trace elements (lead, cadmium, and aluminum) did not exceed physiologically acceptable levels, while their content in hairs may be a biological indicator of their accumulation in the body.
Protasova
O V
OV
Semenov Institute of Chemical Physics, Russian Academy of Sciences, Kosygina 4, Moscow, 117334 Russia.
Maksimova
I A
IA
Cheprasov
V Iu
VIu
Nikiforov
A M
AM
D000328:Adult; D006197:Hair / Q000737:chemistry / Q000378:metabolism* / Q000528:radiation effects; D006440:Hemofiltration; D006801:Humans; D008297:Male; D008670:Metals / Q000032:analysis / Q000378:metabolism*; D008875:Middle Aged; D011210:Power Plants; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000097:blood / Q000378:metabolism*; D018788:Radioactive Hazard Release; D013057:Spectrum Analysis; D013455:Sulfur / Q000032:analysis / Q000378:metabolism; D013997:Time Factors; D014455:Ukraine
D008670:Metals; D013455:Sulfur
Izmenenie makro- i mikroélementnogo balansa v syvorotke krovi, ee ul'trafil'trate i volosakh v otdalennye sroki posle vozdeĭstviia malykh doz ioniziruiushcheĭ radiatsii.