title: Effect of a bicarbonate-containing dentifrice on pH changes in a gel-stabilized plaque after exposure to sucrose.
abstract: Because many factors influence the acid-forming ability of dental plaque in the mouth, a model system was used in which reproducible Stephan curves could be generated after exposure of a gel-stabilized plaque to sucrose. Simulation of the use of a high-bicarbonate dentifrice at a time when plaque pH had fallen to about 4.5 caused a rapid return of the pH toward neutrality, whereas simulation of the use of a low-bicarbonate dentifrice had much less effect.
authors.affiliation: Faculty of Dentistry, University of Manitoba, Winnipeg, Manitoba, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Dawes
mesh_terms: D000143:Acids; D000704:Analysis of Variance; D003773:Dental Plaque / Q000503:physiopathology*; D003802:Dentifrices / Q000627:therapeutic use*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D015203:Reproducibility of Results; D012464:Saliva, Artificial / Q000494:pharmacology; D017693:Sodium Bicarbonate / Q000627:therapeutic use*; D013395:Sucrose / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000143:Acids; D003802:Dentifrices; D012464:Saliva, Artificial; D013395:Sucrose; D017693:Sodium Bicarbonate