A new triterpenoidal saponin from Ixeris sonchifolia and its cytotoxic activity.
A new triterpenoidal saponin, echinocystic acid 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranoside (1), was isolated from Ixeris sonchifolia. Its structure was elucidated on the basis of full spectral data analysis and chemical methods. The cytotoxic activity of compound 1 was evaluated using the tumor cell lines of A375, Hela, and L929 in vitro.
Feng
X Z
XZ
Department of Natural Product Chemistry, Shenyang Pharmaceutical University, Shenyang, P.R. China.
Dong
M
M
Xu
S X
SX
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009828:Oleanolic Acid / Q000031:analogs & derivatives*; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000302:isolation & purification* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D012503:Saponins; D014315:Triterpenes; C435345:echinocystic acid 3-O-glucopyranosyl-(1-3)-arabinopyranoside; D009828:Oleanolic Acid