title: A new reconstructive procedure after segmental pancreatectomy: an experimental study of pancreatic end-to-end (duct-to-duct) anastomosis.
abstract: We produced experimental models of pancreatic end-to-end anastomosis, including ductal end-to-end anastomosis (with or without stent) and pancreaticojejunostomy, using mongrel dogs, with a view to evaluating reconstructive procedures after segmental pancreatectomy. We examined macroscopic findings, pancreatograms, and microangiographic and histopathological findings to determine whether pancreatic end-to-end anastomosis was as practicable as pancreaticojejunostomy. Macroscopic findings showed no suture failure in any animal in the end-to-end anastomosis group. Pancreatography revealed obstruction of the stent tube in the stent subgroup, but good patency in the no-stent subgroup. On the imaging of the microvasculature in the end-to-end anastomosis group, proliferation of neovascular vessels and formation of communicating vessels were detected. Histopathologically, no suture failure was detected, and the viability of the pancreatic end-to-end anastomosis was confirmed. From this experiment, we concluded it that it was possible to employ pancreatic end-to-end anastomosis after segmental pancreatectomy in the clinical situation.
authors.affiliation: Department of Surgery, Division of General and Gastroenterological Surgery, Showa University, School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Ota
authors.forename: M
authors.initials: M
authors.lastname: Kusano
authors.forename: H
authors.initials: H
authors.lastname: Ishii
authors.forename: M
authors.initials: M
authors.lastname: Hoshino
authors.forename: A
authors.initials: A
authors.lastname: Nakamura
authors.forename: Y
authors.initials: Y
authors.lastname: Koike
authors.forename: T
authors.initials: T
authors.lastname: Enosawa
authors.forename: S
authors.initials: S
authors.lastname: Oyama
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000792:Angiography; D000818:Animals; D004285:Dogs; D023421:Models, Animal; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010180:Pancreatectomy; D010182:Pancreatic Diseases / Q000601:surgery*; D010193:Pancreaticojejunostomy / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D015607:Stents; D013536:Suture Techniques