title: Personality abnormality in severe mental illness and its influence on outcome of intensive and standard case management: a randomised controlled trial.
abstract: One hundred fifty-five (77%) of 201 participants recruited in a trial of intensive vs standard case management of patients with recurrent psychotic illness had their personality status measured before treatment and were followed up for two years. The primary outcome was the total number of days spent in psychiatric hospitalisation in the two years following randomisation. Thirty-three (21%) of the patients had a personality disorder and their duration of hospital stay (105 days) was greater than in those without personality disorder (56 days). There was weak evidence that intensive case management more effective in reducing the duration of care in those with personality disorder than in those without personality disorder.
authors.affiliation: Department of Public Mental Health, Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, Paterson Centre, 20 Wharf Road, London W2 1PD, UK.
authors.forename: P
authors.initials: P
authors.lastname: Tyrer
authors.forename: C
authors.initials: C
authors.lastname: Manley
authors.forename: E
authors.initials: E
authors.lastname: Van Horn
authors.forename: D
authors.initials: D
authors.lastname: Leddy
authors.forename: O C
authors.initials: OC
authors.lastname: Ukoumunne
mesh_terms: D000328:Adult; D019090:Case Management / Q000191:economics; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008297:Male; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care; D010554:Personality Disorders / Q000175:diagnosis / Q000191:economics / Q000534:rehabilitation*; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis / Q000191:economics / Q000534:rehabilitation*; D012559:Schizophrenia / Q000191:economics / Q000534:rehabilitation*; D012565:Schizophrenic Psychology