Two new steroidal derivatives from the fruit body of Chlorophyllum molybdites.
Two new steroid derivatives, (22E,24R)-3alpha-ureido-ergosta-4,6,8(14),22-tetraene (1) and (22E,24R)-5alpha,8alpha-epidioxyergosta-6,9,22-triene-3beta-ol 3-O-beta-D-glucopyranoside (2) were isolated from the fruit bodies of Chlorophyllum molybdites (Agaricaceae). The structures were established by spectroscopic and chemical methods. These compounds exhibited cytotoxicity against Kato III cells.
Yoshikawa
K
K
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan. yosikawa@ph.bunri-u.ac.jp
Ikuta
M
M
Arihara
S
S
Matsumura
E
E
Katayama
S
S
D000363:Agaricales / Q000737:chemistry* / Q000166:cytology / Q000254:growth & development*; D006801:Humans; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D014407:Tumor Cells, Cultured / Q000166:cytology / Q000187:drug effects
D010936:Plant Extracts; D013256:Steroids