Evaluation of bone and collagen metabolism by assessing urinary biomarkers in non-human primates.
The purpose of this investigation was to evaluate mineralized and non-mineralized connective tissue responses of non-human primates to microgravity by non-invasive analysis of urinary biomarkers.
Martinez
D A
DA
Connective Tissue Physiology Laboratory, Department of Biology and Biochemistry, University of Houston, TX, USA.
Buckendahl
P E
PE
Grindeland
R E
RE
Dotsenko
M A
MA
Bigbee
A J
AJ
Vailas
A C
AC
D000596:Amino Acids / Q000378:metabolism / Q000652:urine; D000818:Animals; D015415:Biomarkers / Q000652:urine; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism / Q000652:urine; D003094:Collagen / Q000378:metabolism*; D003404:Creatinine / Q000378:metabolism / Q000652:urine; D006909:Hydroxyproline / Q000378:metabolism / Q000652:urine; D008253:Macaca mulatta; D008297:Male; D015675:Osteocalcin / Q000378:metabolism / Q000652:urine; D013026:Space Flight; D014893:Weightlessness
D000596:Amino Acids; D015415:Biomarkers; D015675:Osteocalcin; C015484:pyridinoline; C036020:deoxypyridinoline; D003094:Collagen; D003404:Creatinine; D006909:Hydroxyproline; D002118:Calcium