title: Effects of blasting fumes on exposure and short-term lung function changes in tunnel construction workers.
abstract: OBJECTIVE
  This study attempts to determine the effects of exposure to blasting fumes and its influence on the lung function of tunnel workers.
  
  
  METHODS
  Two groups of tunnel workers, one using ammonium nitrate fuel oil (ANFO) as the explosive and the other using size-sensitized emulsion (SSE), with 24 workers per group, were compared with a reference group (N=34) with low exposure. Spirometry was used to determine lung function. Personal exposure to total and respirable dust, alpha-quartz, volatile organic compounds, oil mist and vapors, formaldehyde, nitrogen dioxide, and carbon monoxide was measured.
  
  
  RESULTS
  The ANFO workers were more exposed to all the agents than the reference group and more exposed than the SSE workers to all the agents except total dust and carbon monoxide. The SSE workers were significantly more exposed to total dust and alpha-quartz than the reference group. High peak exposures to nitrogen dioxide (up to 20 ppm) occurred for the ANFO workers in contrast to the SSE workers, whose exposure did not exceed 2 ppm. The lung function of the ANFO workers significantly decreased by 3% for forced vital capacity, 7% for forced expiratory volume in 1 second, and 8% for forced expiratory flow rate from 25% to 75% of the forced vital capacity over the 11-day period. The changes were reversible. There were no significant changes among the SSE workers and the outdoor workers. The ANFO workers had a significant decrease in FEV1.0 when compared with both the SSE and outdoor workers.
  
  
  CONCLUSIONS
  Tunnel workers using ANFO explosive show a temporary reduction in lung function, whereas those using SSE do not. The most likely explanation for the observed changes is peak exposures to nitrogen dioxide.
authors.affiliation: National Institute of Occupational Health, Oslo, Norway. bba@stami.no
authors.forename: B
authors.initials: B
authors.lastname: Bakke
authors.forename: B
authors.initials: B
authors.lastname: Ulvestad
authors.forename: P
authors.initials: P
authors.lastname: Stewart
authors.forename: M B
authors.initials: MB
authors.lastname: Lund
authors.forename: W
authors.initials: W
authors.lastname: Eduard
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D004738:Engineering; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000503:physiopathology; D008875:Middle Aged; D009664:Norway; D016273:Occupational Exposure / Q000009:adverse effects*; D012129:Respiratory Function Tests; D012907:Smoking
chemical_list: D000395:Air Pollutants, Occupational