New indole alkaloids from Sarcocephalus latifolius.
Phytochemical investigation of the root extract of Sarcocephalus latifolius has led to the isolation of the new indole alkaloids 21-O-methylstrictosamide aglycone and 21-O-ethylstrictosamide aglycone, together with strictosamide, angustine, nauclefine, angustidine, angustoline, 19-O-ethylangustoline, naucleidinal, 19-epi-naucleidinal, quinovic acid-3 beta-O-beta-D-fucopyranoside, quinovic acid-3 beta-O-alpha-L-rhamnopyranoside, scopoletin, and beta-sitosterol. Strictosamide displayed moderate antiplasmodial activity against Plasmodium falciparum.
Abreu
P
P
Departamento de Química, CQFB, FCT-UNL, 2825-114 Caparica, Portugal.
Pereira
A
A
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D007211:Indoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D019666:Rubiaceae / Q000737:chemistry*
D000470:Alkaloids; D007211:Indoles