title: Pharmacotherapy or psychotherapy?: effective treatment for FSD related to unresolved childhood sexual abuse.
abstract: Childhood sexual abuse (CSA) is the form of sexual victimization most correlated with sexual dysfunction in adulthood (Atkeson, Calhoun, Resick, & Ellis, 1994; Sarwer & Durlak, 1996; Laumann, Paik, & Rosen, 1999). The goal of this study was to address the sexual ramifications of unresolved CSA and consider the effectiveness of vasoactive pharmacotherapy, specifically sildenafil, for the treatment of women with unresolved CSA. The sample included 35 women (mean age, 45 years) who presented to a sexual health clinic and who were not of childbearing potential. Of the sample 7 women (23%) had a history of unresolved CSA. Following a psychosexual history and medical evaluation, all women were treated with 100 mg of sildenafil, to be used over a 6-week period at home. When home doses were complete, participants filled out the FIEI, a valid and reliable 5-item questionnaire asking about sexual response post sildenafil. Parameters of sexual response included vaginal lubrication, amount and quality of sensation, satisfaction with intercourse, and ability to reach orgasm. Trends were calculated comparing women with and without unresolved CSA history. A minority of women with CSA responded positively to sildenafil.
authors.affiliation: Department of Urology, UCLA Medical Center, 924 Westwood Ave. #520, Los Angeles, CA 90024, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Berman
authors.forename: J R
authors.initials: JR
authors.lastname: Berman
authors.forename: D
authors.initials: D
authors.lastname: Bruck
authors.forename: R V
authors.initials: RV
authors.lastname: Pawar
authors.forename: I
authors.initials: I
authors.lastname: Goldstein
mesh_terms: D000328:Adult; D002648:Child; D002650:Child Abuse, Sexual / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010549:Personal Satisfaction; D010726:Phosphodiesterase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D010879:Piperazines / Q000008:administration & dosage / Q000627:therapeutic use*; D011613:Psychotherapy; D011687:Purines; D020018:Sexual Dysfunctions, Psychological / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy*; D000068677:Sildenafil Citrate; D013450:Sulfones; D011795:Surveys and Questionnaires
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate