Wang resin-type linker containing a nitro group for polymer support oligosaccharide synthesis: polymer-supported glycosyl donor.
A nitro-introduced Wang resin-type linker for soluble and insoluble polymer support oligosaccharide synthesis is described. The linker was used for connecting glycosyl donors and polymer supports, and was completely stable under the glycosylation conditions tested. The cleavage of the linker was performed under reductive conditions without affecting the protecting groups to release disaccharides.
Manabe
S
S
RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, Japan.
Ito
Y
Y
D002240:Carbohydrate Sequence; D006031:Glycosylation; D007202:Indicators and Reagents; D008969:Molecular Sequence Data; D009574:Nitro Compounds / Q000737:chemistry; D009844:Oligosaccharides / Q000138:chemical synthesis*; D011108:Polymers; D012116:Resins, Plant
D007202:Indicators and Reagents; D009574:Nitro Compounds; D009844:Oligosaccharides; D011108:Polymers; D012116:Resins, Plant