[Determination of disease severity and state of cell membranes in children with Hirschsprung's disease].
For individual approach to assessment of the disease severity in children with Hirschsprung's disease and efficacy of treatment it was proposed to perform monitoring of level of middle mass molecules in blood, values of catabolic pool, osmotic resistance of erythrocytes and free hemoglobin. These criteria permitted to reveal in all the patients with Hirschsprung's disease intoxication of different degree and disintegrity of cellular membranes. It is easy to apply these highly informative methods in any clinical laboratory.
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D015415:Biomarkers; D002462:Cell Membrane / Q000378:metabolism; D002648:Child; D004731:Endotoxins / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D006454:Hemoglobins / Q000032:analysis; D006627:Hirschsprung Disease / Q000097:blood / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D009995:Osmosis; D012720:Severity of Illness Index; D013056:Spectrophotometry, Ultraviolet
D015415:Biomarkers; D004731:Endotoxins; D006454:Hemoglobins