title: [Diagnostic significance of isoenzymes and isoforms of alkaline phosphatase in blood serum of patients with multiple sclerosis on the clinical form of the illness].
abstract: In multiple sclerosis there takes place a gradual destruction of most organs and tissues of the sick organism. With progression of the illness changes are noticeable in their functional development. A biochemical mode of assessment of functioning of organs and tissues is analysis of alkaline phosphatase, which is performed with high dilution. Activity of alkaline phosphatase was measured together with its isoenzymes and isoforms in blood serum of 101 patient with disseminated sclerosis depending on the clinical form of the illness. Measurement of blood serum alkaline phosphatase isoenzymes and isoforms can be a marker of the demyelinating process in multiple sclerosis.
authors.forename: T I
authors.initials: TI
authors.lastname: Nehrych
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D004796:Clinical Enzyme Tests; D015331:Cohort Studies; D006801:Humans; D007201:Indicator Dilution Techniques; D007527:Isoenzymes / Q000097:blood; D009103:Multiple Sclerosis / Q000097:blood / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D007527:Isoenzymes; D000469:Alkaline Phosphatase