title: Ovarian size and response to laparoscopic ovarian electro-cauterization in polycystic ovarian disease.
abstract: OBJECTIVE
  To evaluate endocrine and ovulatory changes in polycystic ovarian disease (PCOD) in relation to patients' ovarian size.
  
  
  METHODS
  Three hundred and seventy-one women with clomiphene citrate-resistant PCOD underwent laparoscopic ovarian cauterization [type I or typical with ovarian volume >8 cm(3) or cross-sectional area >10 cm(2) (n=211), type II with normal size ovary (n=160)]. Serum levels of LH, FSH, DHEAS, PRL, and T before and 10 days after ovarian cautery, spontaneous and induced ovulation and pregnancy rates were compared.
  
  
  RESULTS
  Both groups responded to therapy in a similar manner, with a marked decrease in LH, FSH, DHEAS and T levels, with ovulation rates in type I 90.99%, type II 88.75% and pregnancy rates, 73.45% and 71.25%, respectively, with no statistical differences.
  
  
  CONCLUSIONS
  Hormonal changes, ovulation and pregnancy rates were similar in the two types of PCOD, therefore it can be concluded that ovarian size is not a prognostic factor for response of PCOD patients to laparoscopic ovarian electro-cauterization.
authors.affiliation: Division of Infertility and Endoscopy, Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, Iran. alborzis@sums.ac.ir
authors.forename: S
authors.initials: S
authors.lastname: Alborzi
authors.forename: R
authors.initials: R
authors.lastname: Khodaee
authors.forename: M E
authors.initials: ME
authors.lastname: Parsanejad
mesh_terms: D000328:Adult; D004564:Electrocoagulation; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D010535:Laparoscopy; D010053:Ovary / Q000473:pathology*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000473:pathology / Q000601:surgery*; D011247:Pregnancy; D018873:Pregnancy Rate; D011379:Prognosis
chemical_list: D012739:Gonadal Steroid Hormones