[Anorexia nervosa or somatic disease].
We have studied 18 patients with anorexia nervosa with antroduodenal manometry for 24 hours and also 24 hours oesophageal pH studies. After the first 12 hours of measurements we started treatment with Cisapride (n = 8) or Erythromycin (n = 10) in a blind study. The results of measurements reveal a severe gastroesophageal reflux in 4 patients. Antroduodenal manometry showed dysfunctions in gastric motility, without relation with weight loss or duration of the disease. Cisapride and more so Erythromycin favor gastrointestinal motility.
García Aroca
J
J
Servicio de Cirugía Pediátrica, Hospital Niño Jesús, Avda. Menéndez Pelayo 65, 28009 Madrid.
Alonso Calderón
J L
JL
García Redondo
C
C
Rollán Villamarín
V
V
D000293:Adolescent; D000856:Anorexia Nervosa / Q000175:diagnosis* / Q000503:physiopathology; D020117:Cisapride / Q000627:therapeutic use; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D005764:Gastroesophageal Reflux / Q000188:drug therapy / Q000503:physiopathology; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D005769:Gastrointestinal Motility; D006801:Humans; D008297:Male; D008365:Manometry; D013001:Somatoform Disorders / Q000175:diagnosis* / Q000503:physiopathology
D005765:Gastrointestinal Agents; D004917:Erythromycin; D020117:Cisapride