title: Modified cyclobutane carbonucleosides: synthesis and evaluation of their antiviral activity.
abstract: The synthesis of some 9-(2-cyclobutylethyl)guanine derivatives and analogous carbonucleosides from 1S-alpha-pinene is here presented. None of them showed detectable selectivity when assayed in the performed anti-viral tests.
authors.affiliation: Dpto. Química Orgánica, Facultad de Farmacia, Universidad de Santiago, E-15706 Santiago de Compostela, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Fernández
authors.forename: A R
authors.initials: AR
authors.lastname: Hergueta
authors.forename: C
authors.initials: C
authors.lastname: López
authors.forename: E
authors.initials: E
authors.lastname: De Clercq
authors.forename: J
authors.initials: J
authors.lastname: Balzarini
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D003503:Cyclobutanes / Q000138:chemical synthesis* / Q000494:pharmacology*; D009705:Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D000998:Antiviral Agents; D003503:Cyclobutanes; D009705:Nucleosides