Molecular architecture of adherens junctions.
Adherens junctions are composed of a cadherin-catenin complex and its associated proteins. Recently, an increasing number of novel members of adherens junctions, including membrane and PDZ proteins, have been reported. Interactions among these components in adherens junctions seem to be dynamically regulated during the formation of adherens junction complexes in epithelial cells.
Nagafuchi
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Department of Cellular Interactions, Institute of Molecular Embryology and Genetics, Kumamoto University Honjo 2-2-1, Kumamoto, 860-0811, Japan. naga-san@kaiju.med.kumamoto-u.ac.jp
D022005:Adherens Junctions / Q000737:chemistry* / Q000502:physiology; D000818:Animals; D029742:Caenorhabditis elegans Proteins; D003598:Cytoskeletal Proteins / Q000378:metabolism; D004847:Epithelial Cells / Q000378:metabolism; D015801:Helminth Proteins / Q000378:metabolism; D008565:Membrane Proteins / Q000032:analysis / Q000378:metabolism; D008954:Models, Biological; D009124:Muscle Proteins / Q000378:metabolism; D010750:Phosphoproteins / Q000032:analysis; D015398:Signal Transduction; D062826:Zonula Occludens-1 Protein; D051178:alpha Catenin
D029742:Caenorhabditis elegans Proteins; D003598:Cytoskeletal Proteins; D015801:Helminth Proteins; C099173:LIN-7 protein, C elegans; D008565:Membrane Proteins; D009124:Muscle Proteins; D010750:Phosphoproteins; D062826:Zonula Occludens-1 Protein; D051178:alpha Catenin