Hormonal and metabolic responses of hypophysectomized rats with head-down suspension.
The primary purpose of this investigation was to secure select anatomical and physiological measurements from hypophysectomized rats and their sham-operated control to determine how various endocrine influences could be modified by conditions of simulated microgravity.  The focal point of the study was the exercise responses after head-down suspension; however, we were also interested in obtaining insights on nonexercise-related mechanisms.  Since more details and information concerning this study will be published elsewhere, we will highlight those findings which warrant further research.
Tipton
C M
CM
Department of Exercise & Sport Sciences, The University of Arizona, Tucson 85721, USA.
Grindeland
R E
RE
Woodman
C R
CR
Gosselink
K
K
Linderman
J K
JK
Mukku
V R
VR
Gooselink
K
K
D000818:Animals; D001831:Body Temperature; D004837:Epinephrine / Q000097:blood; D013006:Growth Hormone / Q000097:blood*; D018475:Head-Down Tilt / Q000502:physiology*; D006614:Hindlimb; D007016:Hypophysectomy; D007103:Immobilization / Q000502:physiology*; D008297:Male; D009638:Norepinephrine / Q000097:blood; D010101:Oxygen Consumption; D010902:Pituitary Gland / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013737:Testis / Q000033:anatomy & histology / Q000502:physiology; D013739:Testosterone / Q000097:blood*; D018474:Weightlessness Simulation
D013739:Testosterone; D013006:Growth Hormone; D009638:Norepinephrine; D004837:Epinephrine