title: Effects of alkalinity of household dishwashing liquids on hand skin.
abstract: The objective of this research was to investigate the effects of alkaline pH conditions of dishwashing liquids on hand skin of Korean panelists after repeated exposure. A group of 30 persons with normal hands immersed their hands, for a total of 15 min a day for 4 days, into household cleansing solutions adjusted to pH 7.4, 10.0 and 10.8, respectively. The effects of alkalinity of household cleansing solutions on hand skin were evaluated by measuring overall and dry hand-skin grades, as well as the degrees of hand-skin hydration estimated before and after the repeated immersion exposures to the 3 test products. No statistically-significant difference (p>0.05) was found among the parameters from the repeated immersion exposures to the test products. These findings indicate that increases of pH up to 10.8 of household cleansing solutions did not worsen either overall, dry hand-skin conditions or the level of hand-skin hydration.
authors.affiliation: Quality Assessment Center, Korea Health Industry Development Institute, Seoul 156-050, Korea.
authors.forename: K S
authors.initials: KS
authors.lastname: Park
authors.forename: Y S
authors.initials: YS
authors.lastname: Kim
authors.forename: Y H
authors.initials: YH
authors.lastname: Cho
authors.forename: M Y
authors.initials: MY
authors.lastname: Lee
authors.forename: M S
authors.initials: MS
authors.lastname: Chung
mesh_terms: D017449:Dermatitis, Allergic Contact / Q000209:etiology* / Q000473:pathology; D003902:Detergents / Q000009:adverse effects* / Q000737:chemistry; D006229:Hand Dermatoses / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007101:Immersion; D013997:Time Factors
chemical_list: D003902:Detergents