[Effect of phencarol on pancreatic digestive enzymes in food anaphylaxis].
The effect of the antihistaminic drug phencarol on the activity of pancreatic digestive enzymes was studied in white rats with induced food anaphylaxis. The anaphylaxis is accompanied by significant changes in the activity of digestive enzymes (a complex of protease, lipase, and alpha-amylase), leading to disorders in the splitting and assimilation of proteins, fats, and carbohydrates. Phencarol reduced negative changes in the digestive enzyme secretion system of pancreas.
Ismailov
S R
SR
Department of Pharmacology and Clinical Pharmacology, First State Medical Institute, ul. Al-Kharezmi 25, Urgench, 740000 Uzbekistan.
D000707:Anaphylaxis / Q000188:drug therapy* / Q000201:enzymology / Q000209:etiology; D000818:Animals; D001559:Benzhydryl Compounds / Q000627:therapeutic use*; D004063:Digestion; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000188:drug therapy* / Q000201:enzymology; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D008297:Male; D010179:Pancreas / Q000201:enzymology*; D051381:Rats
D001559:Benzhydryl Compounds; D006634:Histamine H1 Antagonists; C014742:quifenadine