title: Capillary filtration rate, venous compliance, and blood flow in arms and legs do not change during bed rest for 20 days.
abstract: It has been generally accepted that pooling of the blood in the legs is one reason for the orthostatic intolerance experienced after space flights.  This is also the reasoning behind the application of anti-G suits during reentry after space flights.  Fighter pilots also use the anti-G suit, the hypothesis being that this prevents the pooling of blood in the legs.  In order to investigate if immobilization during bed rest would induce peripheral cardiovascular deconditioning we measured capillary filtration rate, venous compliance, and blood flow in arms and legs during bed rest.
authors.affiliation: ESA Medical Support Section, European Astronauts Centre, Cologne, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Bonde-Petersen
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Kawakubo
authors.forename: A
authors.initials: A
authors.lastname: Gunji
mesh_terms: D000328:Adult; D001132:Arm / Q000098:blood supply*; D001510:Bed Rest; D002199:Capillary Permeability / Q000502:physiology*; D002200:Capillary Resistance / Q000502:physiology*; D018493:Cardiovascular Deconditioning / Q000502:physiology; D005260:Female; D006801:Humans; D007024:Hypotension, Orthostatic / Q000175:diagnosis / Q000503:physiopathology; D007866:Leg / Q000098:blood supply*; D008150:Lower Body Negative Pressure; D008297:Male; D010991:Plethysmography; D012039:Regional Blood Flow; D013997:Time Factors; D014655:Vascular Resistance / Q000502:physiology*; D014689:Venous Insufficiency / Q000503:physiopathology; D018474:Weightlessness Simulation