[Immunomodulating and antioxidant effects of vitamins A and E during air and immersion cooling].
An important factor in the immunosuppression development on cooling is the increase in lipid peroxidation rate in the cell membranes. It was found that vitamins A and E possess a high immunomodulating and antioxidant activity under the acute cold-induced stress conditions. Administration of these vitamins is expedient for patients suffered from cooling in air of by immersion.
Uteshev
B S
BS
Pharmacology Department, State Medical University, ul. Ostrovityanova 1, Moscow, 117437 Russia.
Bystrova
N A
NA
Brovkina
I L
IL
Avakian
A R
AR
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000975:Antioxidants / Q000627:therapeutic use*; D002462:Cell Membrane / Q000378:metabolism; D003080:Cold Temperature; D005980:Glutathione Reductase / Q000032:analysis; D006968:Hypersensitivity, Delayed; D007101:Immersion; D015227:Lipid Peroxidation / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000209:etiology / Q000276:immunology* / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000187:drug effects; D014801:Vitamin A / Q000627:therapeutic use*; D014810:Vitamin E / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000975:Antioxidants; D014801:Vitamin A; D014810:Vitamin E; D013482:Superoxide Dismutase; D005980:Glutathione Reductase