title: A mathematical model of the cardiovascular response to +Gz acceleration.
abstract: The cardiovascular system is the limiting factor for human tolerance to positive Gz (head-to-foot) acceleration induced during maneuvers of fighter aircrafts.  Safe handling of modern fighter aircrafts with higher acceleration capabilities require the use of countermeasures such as a G-suit or breathing at a positive pressure.  A better understanding of the mechanisms involved in the cardiovascular response to +Gz acceleration would help improve the design and application of protective measures.  This paper presents a simple mathematical model of the cardiovascular system which incorporates arterial and cardiopulmonary baroreflexes, left ventricular-peripheral circulation interaction and decreased venous return.  This model is capable of reproducing observed overall cardiovascular response to +Gz acceleration.
authors.affiliation: Laboratoire de Médecine Aérospatiale, Centre d'Essais en Vol, Brétigny, France.
authors.forename: F M
authors.initials: FM
authors.lastname: Melchior
authors.forename: R S
authors.initials: RS
authors.lastname: Srinivasan
authors.forename: G
authors.initials: G
authors.lastname: Ossard
authors.lastname: Clère J-M
mesh_terms: D000054:Acceleration; D017704:Baroreflex / Q000502:physiology*; D001794:Blood Pressure; D002498:Centrifugation; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D013318:Stroke Volume / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*