title: Vanillic acid 4-O-beta-D-(6'-O-galloyl) glucopyranoside and other constituents from the bark of Terminalia macroptera Guill.et Perr.
abstract: A new phenolic glucoside gallate, vanillic acid 4-O-beta-D-(6'-O-galloyl) glucopyranoside (1) was isolated from the bark of Terminalia macroptera Guill.et Perr., together with 3,3',4'-tri-O-methylellagic acid (2) and two triterpene glucopyranosyl esters, 24-deoxysericoside (3) and chebuloside II (4). Compounds 2-4, not described previously for this plant, showed antimicrobial activities against Bacillus subtilis, while 3 and 4 possessed haemolytic properties. In both assays 1 was found to be inactive.
authors.affiliation: Institut für Chemie, Lehrstuhl für Organische Chemie, Universität Hohenheim, 70593 Stuttgart, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Conrad
authors.forename: B
authors.initials: B
authors.lastname: Vogler
authors.forename: I
authors.initials: I
authors.lastname: Klaiber
authors.forename: S
authors.initials: S
authors.lastname: Reeb
authors.forename: J H
authors.initials: JH
authors.lastname: Guse
authors.forename: G
authors.initials: G
authors.lastname: Roos
authors.forename: W
authors.initials: W
authors.lastname: Kraus
mesh_terms: D001412:Bacillus subtilis / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects; D047348:Hydrolyzable Tannins; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019685:Rosales / Q000737:chemistry*; D013057:Spectrum Analysis; D013634:Tannins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014641:Vanillic Acid
chemical_list: D047348:Hydrolyzable Tannins; D013634:Tannins; C438453:Vanillic acid 4-O-(6'-O-galloyl) glucopyranoside; D014641:Vanillic Acid