Interactions of nitrogen-containing xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR studies on MAO substrates and inhibitors.
Kalgutkar
A S
AS
Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut 06340, USA. amit_kalgutkar@groton.pfizer.com
Dalvie
D K
DK
Castagnoli
N
N
Taylor
T J
TJ
D000818:Animals; D006801:Humans; D007527:Isoenzymes; D008995:Monoamine Oxidase / Q000187:drug effects* / Q000378:metabolism*; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D016297:Mutagenesis, Site-Directed; D009584:Nitrogen / Q000737:chemistry; D013329:Structure-Activity Relationship; D014018:Tissue Distribution; D015262:Xenobiotics / Q000009:adverse effects* / Q000494:pharmacology
D007527:Isoenzymes; D008996:Monoamine Oxidase Inhibitors; D015262:Xenobiotics; D008995:Monoamine Oxidase; D009584:Nitrogen