title: Efficient synthesis of D-[1'-13C]-ribonucleosides for incorporation into oligo-RNA.
abstract: Syntheses of the monomer building blocks used for the solid-phase synthesis of specifically 1'-13C-labeled oligoribonucleotides from the D-[1-13C]ribose is presented. Procedure has been used for the selective formation of 2'-O-silylated ribonucleosides. After 5'-O-dimethoxytritylation, the synthesis of D-[1'-13C] ribonucleoside phosphoramidites has been achieved.
authors.affiliation: I.C.O.A. associé CNRS, Faculté des Sciences, 45100 Orléans-France.
authors.forename: Y
authors.initials: Y
authors.lastname: Saito
authors.forename: A
authors.initials: A
authors.lastname: Nyilas
authors.forename: L A
authors.initials: LA
authors.lastname: Agrofoglio
mesh_terms: D002247:Carbon Isotopes; D007553:Isotope Labeling / Q000379:methods*; D009943:Organophosphorus Compounds / Q000138:chemical synthesis; D012313:RNA / Q000138:chemical synthesis*; D012263:Ribonucleosides / Q000138:chemical synthesis*
chemical_list: D002247:Carbon Isotopes; D009943:Organophosphorus Compounds; D012263:Ribonucleosides; C434331:phosphoramidite; D012313:RNA