Interspike background activity in extracelullarly recorded Purkinje neurons: spectral analysis.
The aim of this study was to investigate the spectral characteristics of Purkinje cell interspike background activity caused by the occurrence of particular action potentials or by electrically induced enhancement of cerebellar inhibitory and excitatory input drive. Spontaneously active Purkinje neurons were extracellularly recorded in anesthetized rats before and after cessation of stimulation from the inferior olive (10) or locus coeruleus (LC). After A/D conversion (30 kHz), direct spectral analysis of extracted interspike background activity was done. Our results have shown that, in contrast to simple spikes, the occurrence of complex spikes induces changes in the spectra of interspike background activity. The different spectral changes of interspike background activity induced by LC and 10 stimulation also indicated the importance of this extracellularly recorded phenomenon.
Saponjić
J
J
Department of Neurobiology and Immunology, Institute for Biological Research, Belgrade, Yugoslavia. jasnasap@ibiss.bg.ac.yu
Culić
M
M
Janković
B
B
Jovanović
A
A
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D004558:Electric Stimulation; D004594:Electrophysiology; D005110:Extracellular Space; D008125:Locus Coeruleus / Q000502:physiology; D008297:Male; D009433:Neural Inhibition / Q000502:physiology; D009847:Olivary Nucleus / Q000502:physiology; D011689:Purkinje Cells / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar