title: Evaluation of bone and collagen metabolism by assessing urinary biomarkers in non-human primates.
abstract: The purpose of this investigation was to evaluate mineralized and non-mineralized connective tissue responses of non-human primates to microgravity by non-invasive analysis of urinary biomarkers.
authors.affiliation: Connective Tissue Physiology Laboratory, Department of Biology and Biochemistry, University of Houston, TX, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Martinez
authors.forename: P E
authors.initials: PE
authors.lastname: Buckendahl
authors.forename: R E
authors.initials: RE
authors.lastname: Grindeland
authors.forename: M A
authors.initials: MA
authors.lastname: Dotsenko
authors.forename: A J
authors.initials: AJ
authors.lastname: Bigbee
authors.forename: A C
authors.initials: AC
authors.lastname: Vailas
mesh_terms: D000596:Amino Acids / Q000378:metabolism / Q000652:urine; D000818:Animals; D015415:Biomarkers / Q000652:urine; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism / Q000652:urine; D003094:Collagen / Q000378:metabolism*; D003404:Creatinine / Q000378:metabolism / Q000652:urine; D006909:Hydroxyproline / Q000378:metabolism / Q000652:urine; D008253:Macaca mulatta; D008297:Male; D015675:Osteocalcin / Q000378:metabolism / Q000652:urine; D013026:Space Flight; D014893:Weightlessness
chemical_list: D000596:Amino Acids; D015415:Biomarkers; D015675:Osteocalcin; C015484:pyridinoline; C036020:deoxypyridinoline; D003094:Collagen; D003404:Creatinine; D006909:Hydroxyproline; D002118:Calcium