title: Distribution of hepatitis C virus serotypes and duration of infection in HCV infected subjects from a geographical area in Southeast Italy.
abstract: Hepatitis C virus serotypes and the duration of infection HCV positive subjects from a restricted geographical area in Italy, were evaluated. HCV serotypes were determined by Murex serotyping assay. Serotypes were detected in 592 (88.0%) of 669 samples. Type 1 proved to be the most frequent (48.9%), followed by types 2 (29%), 3(4.5%) and 4 (2.1%). The transmission of HCV 3 and 4 were observed only in the past 20 years whilst those of other types were recorded during 40 or more years. The results support the view that the prevalence of different HCV types of infection in one restricted geographical area may be associated with the source and duration of infection.
authors.affiliation: Dipartimento di Clinica Medica, Immunologia e Malattie Infettive, Univerità degli Studi di Bari, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Sacco
authors.forename: F
authors.initials: F
authors.lastname: Stella
authors.forename: R
authors.initials: R
authors.lastname: Leva
authors.forename: A
authors.initials: A
authors.lastname: Volpe
authors.forename: C
authors.initials: C
authors.lastname: Ranieri
authors.forename: A
authors.initials: A
authors.lastname: Pellegrino
authors.forename: C
authors.initials: C
authors.lastname: Picciarelli
authors.forename: R
authors.initials: R
authors.lastname: Buongiorno
authors.forename: P
authors.initials: P
authors.lastname: Dentico
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D016174:Hepacivirus / Q000145:classification* / Q000276:immunology; D006526:Hepatitis C / Q000453:epidemiology* / Q000503:physiopathology* / Q000821:virology; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012703:Serotyping; D013997:Time Factors
chemical_list: D018937:Hepatitis C Antibodies