[Blood interleukin-8 in patients with different stages of chronic relapsing pancreatitis and its role in the pathogenesis of pancreatitis].
Interleukin-8 was examined in 55 patients with chronic relapsing pancreatitis in the stage of aggravation, change to remission and stable remission. The highest interleukin-8 was revealed in the patients with aggravation of pancreatitis. The author considers, that interleukin-8 is connected with high concentration of oxygen active forms in neutrophils in the patients with this stage of disease. It is concluded, that interleukin-8 takes part in the pathogenesis of relapsing pancreatitis. High levels of interleukin-8 were revealed in some patients with stable pancreatitis remission. The author thinks, that asymptomatic pancreatitis relapses may be present.
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D002908:Chronic Disease; D006801:Humans; D016209:Interleukin-8 / Q000097:blood*; D010195:Pancreatitis / Q000097:blood* / Q000175:diagnosis; D012008:Recurrence; D012720:Severity of Illness Index
D016209:Interleukin-8