title: Effects of heavy ions on inactivation and DNA double strand breaks in Deinococcus radiodurans R1.
abstract: Inactivation and double strand break (dsb) induction after heavy ion irradiation were studied in stationary phase cells of the highly radiation resistant bacterium Deinococcus radiodurans R1.  There is evidence that the radiation sensitivity of this bacterium is nearly independent on energy in the range of up to 15 MeV/u for lighter ions (Ar). The responses to dsb induction for charged particles show direct relationship between increasing radiation dose and residual intact DNA.
authors.affiliation: DLR, Institute of Aerospace Medicine, Koln, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Zimmermann
authors.forename: M
authors.initials: M
authors.lastname: Schafer
authors.forename: C
authors.initials: C
authors.lastname: Schmitz
authors.forename: H
authors.initials: H
authors.lastname: Bucker
mesh_terms: D001128:Argon; D004249:DNA Damage; D004269:DNA, Bacterial / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D016521:Electrophoresis, Gel, Pulsed-Field; D006095:Gram-Positive Cocci / Q000235:genetics / Q000528:radiation effects*; D007854:Lead; D009532:Nickel; D010315:Particle Accelerators; D011836:Radiation Tolerance; D011839:Radiation, Ionizing
chemical_list: D004269:DNA, Bacterial; D007854:Lead; D001128:Argon; D009532:Nickel