title: [Effect of the lavage of the digestive tract on microflora in patients with polyps in the large intestine].
abstract: The microbial status of the intestine and the influence of lavage with polyethylene glycol and balanced electrolyte solution (PEG + E), used in the process of the preparation of patients to polypectomy, on this status were evaluated. The study of microflora was made before oral lavage after, and 48-72 hours later its completion. For control, a group of healthy volunteers, also subjected to oral lavage with PEG + E, was used. The lavage of the digestive tract with PEG + E led to a sharp change in the microbial status in both groups. Some microorganisms, previously absent in the intestine, were found after lavage. The processes of the restoration of intestinal microflora after lavage in healthy volunteers and in patients with polyps had certain differences. In healthy volunteers intestinal microflora was completely restored, and even improved, 48-72 hours after lavage with PEG + E, while at the expiration of this time intestinal microflora in the patients with polyps could be characterized as dysbiotic.
authors.affiliation: Institute of Medico-Social Rehabilitology, State Medical University, Moscow, Russia.
authors.forename: V M
authors.initials: VM
authors.lastname: Korshunov
authors.forename: L V
authors.initials: LV
authors.lastname: Potashnik
authors.forename: O V
authors.initials: OV
authors.lastname: Korshunova
authors.forename: V V
authors.initials: VV
authors.lastname: Smeianov
authors.forename: B A
authors.initials: BA
authors.lastname: Efimov
authors.forename: K
authors.initials: K
authors.lastname: Gyr
authors.forename: R
authors.initials: R
authors.lastname: Frei
authors.forename: H
authors.initials: H
authors.lastname: Reber
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D003106:Colon / Q000382:microbiology*; D003111:Colonic Polyps / Q000382:microbiology*; D004573:Electrolytes; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols; D007507:Therapeutic Irrigation
chemical_list: D004573:Electrolytes; D011092:Polyethylene Glycols