title: Methadone may promote HIV replication: study.
abstract: Investigators at the University of Pennsylvania School of Medicine have found that HIV replication in vitro is promoted by the opiate methadone. Although this research is a long way from concluding that injection-drug-using HIV patients should avoid methadone treatment, it does raise questions that will need to be answered through further studies.
authors.affiliation: Section of Immunology, Children's Hospital of Philadelphia, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: Douglas
mesh_terms: D006678:HIV / Q000235:genetics / Q000502:physiology*; D016325:HIV Long Terminal Repeat; D006801:Humans; D008691:Methadone / Q000494:pharmacology* / Q000627:therapeutic use; D019713:Receptors, CCR5 / Q000235:genetics; D014779:Virus Replication / Q000187:drug effects*
chemical_list: D019713:Receptors, CCR5; D008691:Methadone