title: Interaction of oligonucleotides with cellular proteins.
abstract: Oligonucleotides (ODNs) conjugated to 4-[(N-2-chloroethyl-N-methyl)amino] benzylamine were used to investigate ODN-binding proteins in cells of different origin. The data obtained demonstrate that 68, 46, 38 and 28 kDa ODN-binding proteins are universal for tested cell lines.
authors.affiliation: Institute of Bioorganic Chemistry, Siberian Division of Russian Academy of Sciences, pr. Lavrentieva 8, Novosibirsk 630090, Russia.
authors.forename: P
authors.initials: P
authors.lastname: Laktionov
authors.forename: B
authors.initials: B
authors.lastname: Chelobanov
authors.forename: E
authors.initials: E
authors.lastname: Rykova
authors.forename: V
authors.initials: V
authors.lastname: Vlassov
mesh_terms: D016475:3T3 Cells; D000818:Animals; D001345:Autoradiography; D019556:COS Cells; D003600:Cytosol / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D020014:K562 Cells; D008565:Membrane Proteins / Q000378:metabolism*; D051379:Mice; D009150:Mustard Compounds / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism*; D009841:Oligonucleotides / Q000378:metabolism*; D010761:Phosphorus Radioisotopes; D011485:Protein Binding
chemical_list: D008565:Membrane Proteins; D009150:Mustard Compounds; D009687:Nuclear Proteins; D009841:Oligonucleotides; D010761:Phosphorus Radioisotopes; C025881:4(N)-(2-chloroethyl-N-methylamino)benzylamine