[Antioxidant properties of novel preparations--bioflavonoid derivatives and tannins].
New medicinal plant preparations of polyphenol nature, representing the derivatives of bioflavonoids (piflamin) and ellagotannins (altan and ellagic acid) were experimentally studied. The drugs exhibited antioxidant properties, which were manifested by inhibition of a pathological lipid peroxidation, restoration of the functional activity of the antioxidant system components, and stabilization of the hepatocyte membranes.
Iakovleva
L V
LV
Central Research Laboratory, Ukrainian Pharmaceutical Academy, ul. Pushkinskaya 53, Kharkov, 310002 Ukraine.
Gerasimova
O A
OA
Karbusheva
I V
IV
Ivakhnenko
A K
AK
Buniatian
N D
ND
Sakharova
T S
TS
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism; D002462:Cell Membrane; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism; D004610:Ellagic Acid / Q000494:pharmacology*; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D022781:Hepatocytes / Q000187:drug effects / Q000648:ultrastructure; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D051379:Mice; D051381:Rats; D013634:Tannins / Q000494:pharmacology*
D000975:Antioxidants; D005419:Flavonoids; D013634:Tannins; D004610:Ellagic Acid