title: Histiocytic ulcerative colitis in three non-boxer dogs.
abstract: Histiocytic ulcerative colitis (HUC) is described in three non-boxer dogs. Clinical signs were typical of large-bowel diarrhea and included soft stool, hematochezia, tenesmus, and an increased frequency of defecation. Diagnosis in each case was made by light microscopic evaluation of endoscopically obtained colonic biopsy specimens. Treatment regimes varied, but included immunosuppressive agents, anti-inflammatory drugs, antimicrobials, and dietary modification. Clinical response was substantial in two patients, while the third patient was euthanized due to treatment failure. The authors' observations indicate that HUC may be encountered in non-boxer dogs.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Stokes
authors.forename: J M
authors.initials: JM
authors.lastname: Kruger
authors.forename: T
authors.initials: T
authors.lastname: Mullaney
authors.forename: K
authors.initials: K
authors.lastname: Holan
authors.forename: W
authors.initials: W
authors.lastname: Schall
mesh_terms: D000818:Animals; D001947:Breeding; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000628:therapy; D004285:Dogs; D005260:Female; D008297:Male; D012189:Retrospective Studies