title: [Fever of central origin during stroke].
abstract: BACKGROUND
  Fever appears in a fourth of stroke, approximately. Its origins, (the most of them are infectious) are unknown in a minority of the cases. Some hypotheses indicate that central mechanisms like hypothalamic lesions or segregation of endogenous pyrogens may be implicated.
  
  
  OBJECTIVE
  To evaluate the frequency of central fever during stroke and to notice if there are clinical differences between infectious and central origins of the fever.
  
  
  METHODS
  103 patients were evaluated prospectively, if someone had fever, an investigation about an infectious origin was made. We divided the fever patients into two groups: "infectious fever" and "fever without infection documented" and we analyzed the clinical differences between them.
  
  
  RESULTS
  23% of the patients had fever, 33% without infection documented. This last group had earlier fevers. They had more clinical severity and more mortality. The fever was higher and it didn't response to the antipyretic treatment also. The others parameters didn't show any difference between the two groups.
  
  
  CONCLUSIONS
  The patients with fever without infection documented ( probably fever of central origin)had a defined model with its own characteristics, in a different way from infectious fever.
authors.affiliation: Sección de Neurología; Hospital Santa María del Rosell, Cartagena, 30203, España. amoraleso@meditex.es
authors.forename: A
authors.initials: A
authors.lastname: Morales-Ortiz
authors.forename: M
authors.initials: M
authors.lastname: Jiménez-Pascual
authors.forename: J A
authors.initials: JA
authors.lastname: Pérez-Vicente
authors.forename: A
authors.initials: A
authors.lastname: Monge-Arguiles
authors.forename: J
authors.initials: J
authors.lastname: Bautista-Prados
mesh_terms: D000368:Aged; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D005334:Fever / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007239:Infections / Q000150:complications / Q000503:physiopathology; D008297:Male; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000150:complications / Q000503:physiopathology; D020521:Stroke / Q000150:complications* / Q000503:physiopathology; D017211:Treatment Failure; D014552:Urinary Tract Infections / Q000150:complications / Q000503:physiopathology
chemical_list: D018712:Analgesics, Non-Narcotic