[Humoral immunodeficiencies in asthmatic children with recurrence rhinopharyngitis].
OBJECTIVE
To determine the serum immunoglobulin concentrations in children with asthma and recurrent rinofaringitis.


METHODS
We made a descriptive survey in children with persistent moderate asthma and with recurrent infections. Serum IgA, IgG, IgM and IgE concentrations was determined in the laboratory of Immunology and the results were considered according to the age and to the technique used in the laboratory.


RESULTS
They were 45 patients (26 males and 19 females) with age average of 5.5 +/- 2.8 years +/- SD. In 12 patients (26%) had deficiency of IgA, in 2 (4%) it was absolute and in 10 (22%) it was partially. They were 4 (9%) with deficiency of IgG and IgM had not deficiency, but in 5 (11%) had elevated concentrations. We find 28 patients (62%) with high serum IgE.


CONCLUSIONS
The prevalence of the serum immunodeficiency would be bigger if they were looked for deliberately in groups with risk, like it is demonstrated in this study, where, of the 45 patients they met 18 with some serum immunoglobulin deficiency (40%).
Rodríguez Medina
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R
Alergólogo, Clínica de Asma y Alergia, Hospital General de Zona núm. 30, Iztacalco, Instituto Mexicano del Seguro Social.
Gasca Bauza
M R
MR
D001249:Asthma / Q000097:blood / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood / Q000172:deficiency*; D008297:Male; D010612:Pharyngitis / Q000097:blood / Q000276:immunology*; D012008:Recurrence; D012220:Rhinitis / Q000097:blood / Q000276:immunology*
D007136:Immunoglobulins