title: Management of the carotid artery at the skull base.
abstract: OBJECTIVE
  To determine appropriate management of benign lesions with significant involvement of the carotid artery at the skull base and present an algorithm for safe treatment of these patients.
  
  
  METHODS
  From 1982 to 1999, 115 patients with significant parapharyngeal space masses were treated at our institution. Of these patients, 43 had lesions involving the carotid artery at the skull base and served as the basis for this study. All patients underwent preoperative computed tomography or magnetic resonance imaging scans to determine carotid involvement, and all had preoperative 4-vessel arteriograms and carotid occlusion tests with continuous electroencephalography or neurologic examination monitoring to predict safety of carotid sacrifice.
  
  
  RESULTS
  Of 43 patients, 41 passed carotid occlusion testing and were treated surgically. Of these patients, 33 (81%) underwent resection of their lesions with preservation of the internal carotid artery, 5 (12%) had resection with bypass or reconstruction of the artery, and 3 (7%) had en bloc resections without artery reconstruction. There were no transient or permanent neurologic sequelae in any patient.
  
  
  CONCLUSIONS
  When carotid artery encasement occurs in the setting of benign lesions at the skull base, safe resection with vascular preservation is possible in most cases. If carotid artery resection is necessary, vascular bypass or reconstruction is recommended to minimize neurologic morbidity.
authors.affiliation: Division of Otolaryngology/Head and Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: Meredith
authors.forename: C G
authors.initials: CG
authors.lastname: Shores
authors.forename: V N
authors.initials: VN
authors.lastname: Carrasco
authors.forename: H C
authors.initials: HC
authors.lastname: Pillsbury
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D000783:Aneurysm / Q000000981:diagnostic imaging / Q000601:surgery; D000792:Angiography; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D002340:Carotid Artery Diseases; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009959:Oropharyngeal Neoplasms / Q000175:diagnosis / Q000601:surgery*; D011300:Preoperative Care; D012189:Retrospective Studies; D019291:Skull Base / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D019043:Vascular Neoplasms / Q000175:diagnosis / Q000601:surgery*