title: Artificial G-load and chemical changes of saliva.
abstract: Effectiveness of artificial G load is expected when it is used as a countermeasure against various bio-medical mishaps which are taking place in the micro-gravity environment, and probably more importantly, to prepare re-entry to the earth 1-G environment. Regarding the salivary chemical analysis, it has been known that, in case of (experimental) motion sickness, symptomatic outputs are delivered through the autonomic nervous system, and changes in salivary chemical components occur. In this study, accordingly, quantitative analyses of salivary potassium, sodium, chloride and total protein were performed before and after various levels of G loads which were produced by our short-radius human centrifuge. When the results were compared, the subjects who failed 60 minutes ride exhibited significantly higher post-load levels of potassium and sodium than those of successful 60 minutes riders. However, the differences between two groups were less clear in chloride and total protein. The result of present study indicates that salivary potassium and sodium are good indicators to represent autonomic nervous system function under the stressful condition produced by an artificial G load.
authors.affiliation: University Research Center, Nihon University, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Igarashi
authors.forename: T
authors.initials: T
authors.lastname: Nakazato
authors.forename: K
authors.initials: K
authors.lastname: Yajima
authors.forename: A
authors.initials: A
authors.lastname: Miyamoto
mesh_terms: D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology*; D002498:Centrifugation; D002712:Chlorides / Q000378:metabolism; D018470:Gravity, Altered / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011188:Potassium / Q000378:metabolism; D012463:Saliva / Q000737:chemistry / Q000378:metabolism*; D012471:Salivary Proteins and Peptides / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D013997:Time Factors; D018544:Weightlessness Countermeasures
chemical_list: D002712:Chlorides; D012471:Salivary Proteins and Peptides; D012964:Sodium; D011188:Potassium