title: Study of normal values in coagulation profile.
abstract: The objective of the present work was to study normal values of hemostasis parameters in healthy volunteers using Behring Coagulation Timer (BCT). Plasma was divided into 2 parts fresh plasma and lyophilized plasma. It was found that the mean +/- SD of prothrombin time (PT) and activated partial thromboplastin time (APTT) in fresh plasma (n = 37) were 11.95 + 0.7 and 40.52 +/- 5.30 seconds respectively. The means + SD of coagulation factors I, II, VII, VIII and IX were 2.55 +/- 0.73 g/l (n = 36), 82.28 +/- 10.28 per cent (n = 37), 82.79 +/- 19.36 per cent (n=32), 89.13 +/- 24.17 per cent (n = 37), 94.11 +/- 16.29 per cent (n=31) respectively. The normal ranges (p5-p95) of PT, APTT and coagulation factors I, II, VII, VIII and IX were 10.8-13.3 sec, 31.4-48.0 sec and 1.82-4.65 g/l, 64.83-96.5 per cent, 46.88-113.5 per cent, 52.44-127.61 per cent and 67.87-116.94 per cent respectively. Comparison of PT, APTT between fresh plasma and lyophilized plasma were statistically different (Wilcoxon match-pair signed rank test, p < 0.05), while F I, II, VIII and F.IX in fresh plasma were increased more significantly than lyophilized plasma.
authors.affiliation: Department of Clinical Microscopy, Faculty of Medical Technology, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: K
authors.initials: K
authors.lastname: Pathepchotiwong
authors.forename: P
authors.initials: P
authors.lastname: Tantiniti
authors.forename: C
authors.initials: C
authors.lastname: Sutthithampanich
mesh_terms: D001780:Blood Coagulation Tests; D006801:Humans; D012016:Reference Values