title: [Changes of plasma endocrine hormone in pilots under Coriolis acceleration].
abstract: Plasma endocrine hormones were studied in both 24 motion sickness (orthostatic intolerance) and healthy pilots. Coriolis acceleration of 3.75, 5.00 and 6.25 pi 2 cm/s2 were given with intervals of 3-4 min AT-II, insulin, cortisol, Aldosterone and gastrin were determined by radioimmunoassay. It was found that aldosterone, AT-II, gastrin increased with increase of coriolis acceleration in all pilots. (P < 0.05), but cortisol and insulin only increased in healthy pilots (P < 0.05). It suggests excitation of the autonomic nervous system might be insufficient in orthostatic intolerant pilots and that determination of endocrine hormones may be useful in the evaluation of autonomic nervous activities.
authors.affiliation: Air Force general hospital, Beijing, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Dai
authors.forename: G
authors.initials: G
authors.lastname: Ji
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.forename: X
authors.initials: X
authors.lastname: Sun
authors.forename: F
authors.initials: F
authors.lastname: Dai
mesh_terms: D000054:Acceleration; D000328:Adult; D000450:Aldosterone / Q000097:blood / Q000378:metabolism; D000804:Angiotensin II / Q000097:blood / Q000378:metabolism; D001341:Autonomic Nervous System / Q000503:physiopathology*; D003312:Coriolis Force; D005755:Gastrins / Q000097:blood / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism; D007024:Hypotension, Orthostatic / Q000503:physiopathology; D007328:Insulin / Q000097:blood / Q000378:metabolism; D009041:Motion Sickness / Q000209:etiology / Q000503:physiopathology*
chemical_list: D005755:Gastrins; D007328:Insulin; D000804:Angiotensin II; D000450:Aldosterone; D006854:Hydrocortisone