title: Curative treatment of central hemangioma in the mandible by direct puncture and embolisation with n-butyl-cyanoacrylate (NBCA).
abstract: Management of central hemangioma in the mandible is difficult because of the abundant vascular network in this region. One of the most common signs of these patients, especially in the mixed dentition period, is hypermobility of the teeth with spontaneous hemorrhage from the surrounding gingival sulcus. Various therapeutic modalities have been considered, but surgery is the most frequently used. In cases of a large extensive lesion, however, intralesional injections of sclerosing agents have often been successful. A case of central hemangioma of the mandible with arteriovenous malformations in a 10-year-old girl is reported. She was treated with direct injection of an embolic material, n-butyl-cyanoacrylate, which brought satisfactory results. Preoperative embolisation of feeder vessels with Gelfoam and Avitene soaked in thrombin together with this direct injection is a safe treatment modality that is as effective as surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Nagoya University Postgraduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan. kamohosp@japan-net.or.jp
authors.forename: R
authors.initials: R
authors.lastname: Kaneko
authors.forename: I
authors.initials: I
authors.lastname: Tohnai
authors.forename: M
authors.initials: M
authors.lastname: Ueda
authors.forename: M
authors.initials: M
authors.lastname: Negoro
authors.forename: J
authors.initials: J
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
mesh_terms: D002648:Child; D004621:Embolization, Therapeutic / Q000379:methods*; D004659:Enbucrilate / Q000031:analogs & derivatives / Q000627:therapeutic use*; D005260:Female; D006391:Hemangioma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008339:Mandibular Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D009389:Neovascularization, Pathologic / Q000628:therapy; D011859:Radiography; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D014014:Tissue Adhesives; D004659:Enbucrilate