A method for the diagnosis of primary cutaneous melanoma using surface microscopy.
For a melanoma to be diagnosed, it must have neither of two morphological negative features and one or more of nine positive features. The negative features are symmetry of pattern and a single color. The positive features are blue-white veil, multiple brown dots, pseudopods, radial streaming, scar-like pigmentation, peripheral black dots or globules, five or six colors, multiple blue-gray dots, and a broadened network. This method gives a 92% sensitivity and 71% specificity for the diagnosis of melanoma.
Menzies
S W
SW
Department of Surgery, University of Sydney, Sydney Melanoma Unit, Melanoma and Skin Cover Research Institute, Royal Prince Alfred Hospital, New South Wales, Australia. scott@mel.rpa.cs.nsw.gov.au
D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000295:instrumentation*; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D008853:Microscopy / Q000295:instrumentation; D012878:Skin Neoplasms / Q000473:pathology*