title: Abiogenic synthesis of pyrimidine nucleotides in solid state by vacuum ultraviolet radiation.
abstract: The abiogenic synthesis of pyrimidine nucleotides in solid state has been investigated. Our experiment indicates that natural nucleotides are produced in thin films prepared from nucleoside and inorganic phosphate by irradiating with vacuum ultraviolet light (VUV, lambda=100-200 nm). We have investigated the influence of the type of nucleic acids base (thymidine, cytosine, uracil) and the structure of sugar moiety (ribose or deoxyribose) on the course and yield of reaction. We compared the action of vacuum ultraviolet light with action of gamma-radiation, heat and biology significant UV (254 nm) which have been investigated earlier. The occurrence of these reaction in open space is discussed.
authors.affiliation: Institute of Cytology, St. Petersburg, Russia.
authors.forename: M B
authors.initials: MB
authors.lastname: Simakov
authors.forename: E A
authors.initials: EA
authors.lastname: Kuzicheva
authors.forename: I L
authors.initials: IL
authors.lastname: Malko
mesh_terms: D003562:Cytidine / Q000737:chemistry / Q000528:radiation effects*; D015226:Dinucleoside Phosphates / Q000737:chemistry / Q000528:radiation effects; D019418:Evolution, Chemical; D005118:Extraterrestrial Environment; D009705:Nucleosides / Q000737:chemistry / Q000528:radiation effects; D010766:Phosphorylation; D010777:Photochemistry; D011742:Pyrimidine Nucleotides / Q000138:chemical synthesis*; D013936:Thymidine / Q000737:chemistry / Q000528:radiation effects*; D014466:Ultraviolet Rays; D014618:Vacuum
chemical_list: D015226:Dinucleoside Phosphates; D009705:Nucleosides; D011742:Pyrimidine Nucleotides; D003562:Cytidine; D013936:Thymidine