Temporary granulomatous inflammation following collagen implantation.
Injections of bovine collagen are a common procedure for correction of folds in the face. However, this therapy is not free from side effects. We present a patient in whom a granulomatous inflammation occurred following implantation of this material. We therefore now insist on an observation interval of 4 weeks between test injection and actual treatment, as is recommended by the manufacturer.
Heise
H
H
Klinik und Poliklinik für Dermatologie und Venerologie der Universität Rostock, Germany.
Zimmermann
R
R
Heise
P
P
D020341:Absorbable Implants / Q000009:adverse effects*; D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001672:Biocompatible Materials / Q000008:administration & dosage / Q000009:adverse effects*; D002417:Cattle; D002990:Clobetasol / Q000627:therapeutic use; D003094:Collagen / Q000008:administration & dosage / Q000009:adverse effects*; D005148:Facial Dermatoses / Q000139:chemically induced* / Q000188:drug therapy; D005260:Female; D005938:Glucocorticoids; D015745:Granuloma, Foreign-Body / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced / Q000188:drug therapy; D007279:Injections, Subcutaneous; D008875:Middle Aged; D015595:Skin Aging
D000893:Anti-Inflammatory Agents; D001672:Biocompatible Materials; D005938:Glucocorticoids; D003094:Collagen; D002990:Clobetasol