Synthesis of quinoxaline-3,4-dihydro-6,7-dimethyl-3-keto-4-D-ribityl-2-carboxamide.
Quinoxaline-3,4-dihydro-6,7-dimethyl-3-keto-4-D-ribityl-2-carboxamide (QN, RN: 13698-42-5) was prepared from the corresponding carboxylic acid (QC) and ammonia by using water soluble carbodiimide (WSCD) (Scheme 1). The structure of product was verified by physicochemical properties, especially by comparing the UV and NMR spectroscopic properties of QN and of the acetate with those of QC and riboflavin (RF). [reaction: see text]
Matsui
K
K
Osaka International University for Women. matsuippu@nyc.odn.ne.jp
D002264:Carboxylic Acids / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000737:chemistry; D012256:Riboflavin / Q000737:chemistry
D002264:Carboxylic Acids; D011810:Quinoxalines; C435463:quinoxaline-3,4-dihydro-6,7-dimethyl-3-keto-4-D-ribityl-2-carboxamide; D012256:Riboflavin