Maternal dietary lipids modify composition of bone lipids and ex vivo prostaglandin E2 production in early postnatal Japanese quail.
This study examined the effects of maternal dietary lipids on fatty acid composition and ex vivo prostaglandin E2 (PGE2) biosynthesis in bone tissues of progeny of Japanese quail. Laying hens were fed a basal diet containing soybean oil (SBO), hydrogenated soybean oil (HSBO), poultry fat (PF), or menhaden fish oil (FO) at 50 g/kg of diet. Fertilized eggs were incubated, and newly hatched quail were used for tibial fatty acid analysis and PGE2 measurement or were fed an identical diet until 2 wk of age. Yolks and tibiae of newly hatched quail from hens fed the SBO diet contained higher levels of total n-6 fatty acids and arachidonic acid [AA; 20:4(n-6)], whereas those from hens consuming the FO diet had increased concentrations of total n-3 fatty acids, eicosapentaenoic acid [EPA; 20:5(n-3)], docosapentaenoic acid [22:5(n-3)], docosahexaenoic acid [DHA; 22:6(n-3)], and total saturated fatty acids (SAT) but greatly reduced amounts of AA in egg yolks and tibiae. The maternal diet containing HSBO resulted in the accumulation of trans 18:1 egg yolks and tibiae of newly hatched quails. At 1 wk of age, the concentrations of EPA, DHA, and trans 18:1 in tibiae still reflected the maternal dietary fatty acid profile. At 2 wk of age, however, differences in fatty acid composition between treatments had disappeared. Addition of FO or HSBO to the maternal diet significantly lowered the ex vivo PGE2 production of tibiae in newly hatched quail compared to those from hens fed SBO or PF diet. These results suggest that maternal dietary lipids may have the potential to influence bone metabolism of embryos by modifying the fatty acid composition of this tissue.
Liu
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Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061-0306, USA.
Denbow
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DM
D000821:Animal Feed; D000818:Animals; D003370:Coturnix / Q000378:metabolism / Q000502:physiology*; D004042:Dietary Fats, Unsaturated / Q000378:metabolism / Q000494:pharmacology*; D015232:Dinoprostone / Q000096:biosynthesis*; D004530:Egg Yolk / Q000737:chemistry; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D005395:Fish Oils / Q000378:metabolism / Q000494:pharmacology; D008297:Male; D013977:Tibia / Q000737:chemistry / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism
D004042:Dietary Fats, Unsaturated; D005227:Fatty Acids; D005395:Fish Oils; D015232:Dinoprostone