N-cyanoimidazole and diimidazole imine:  water-soluble condensing agents for the formation of the phosphodiester bond.
The reaction of BrCN with imidazole results in the formation of N-cyanoimidazole and diimidazole imine.  These compounds were shown to be useful condensing agents for the formation of the phosphodiester bound in aqueous solution.
Ferris
J P
JP
Department of Chemistry, Rensselaer Polytechnic Institute, Troy, NY 12180-3590, USA.
Huang
C H
CH
Hagan
W J
WJ
D000227:Adenine Nucleotides / Q000138:chemical synthesis*; D000249:Adenosine Monophosphate / Q000737:chemistry*; D017605:Bromine Compounds / Q000737:chemistry; D003486:Cyanides / Q000737:chemistry; D019143:Evolution, Molecular; D007093:Imidazoles / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D012313:RNA / Q000138:chemical synthesis
D000227:Adenine Nucleotides; D017605:Bromine Compounds; D003486:Cyanides; D007093:Imidazoles; D007097:Imines; D000249:Adenosine Monophosphate; D012313:RNA; C010565:2',3'-cyclic AMP; C051673:N-cyanoimidazole