Why isn't the fetus rejected?
The long-standing question of how the fetal allograft avoids immune rejection during pregnancy has lately been generating renewed interest. Recent insights have emerged from studies in mice on uterine NK cells, NKT cells, complement inhibition and the reproductive effects of 1-methyl-tryptophan.
Erlebacher
A
A
Department of Immunology and Infectious Diseases, Harvard School of Public Health, FXB 205, 651 Huntington Avenue, Boston, MA 02115, USA. aerlebac@hsph.harvard.edu
D000022:Abortion, Spontaneous / Q000276:immunology; D000818:Animals; D005260:Female; D005333:Fetus / Q000276:immunology*; D006084:Graft Rejection / Q000276:immunology*; D006801:Humans; D011247:Pregnancy