title: Double strand breaks in the DNA of Bacillus subtilis cells irradiated by heavy ions.
abstract: Cells of Bacillus subtilis strain TKJ 8431 in stationary phase were irradiated with X-rays (150 kV at DLR) or heavy ions (Ne, Ar, Pb with residual energies between 3 and 15 MeV/u at GSI). The action cross section for the formation of double strand breaks in the DNA of the irradiated cells follows a similar dependence on mass and energy of the ions as has been found for various biological endpoints, e.g. inactivation, mutagenesis and repair efficacy.
authors.affiliation: DLR, Institute of Aerospace Medicine, Koln, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Micke
authors.forename: G
authors.initials: G
authors.lastname: Horneck
authors.forename: S
authors.initials: S
authors.lastname: Kozubek
mesh_terms: D001128:Argon; D001412:Bacillus subtilis / Q000235:genetics / Q000528:radiation effects*; D004249:DNA Damage; D004269:DNA, Bacterial / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D016521:Electrophoresis, Gel, Pulsed-Field; D007854:Lead; D009154:Mutation; D009356:Neon; D010315:Particle Accelerators; D011839:Radiation, Ionizing; D014965:X-Rays
chemical_list: D004269:DNA, Bacterial; D007854:Lead; D009356:Neon; D001128:Argon