Twelve novel HLA-B*15 alleles carrying previously observed sequence motifs are placed into B*15 subgroups.
Twelve new B*15 alleles are described. All of the known B*15 alleles are divided into subgroups based on serologic assignments and/or nucleotide sequence polymorphisms. These groups might be used as a reference for DNA-based testing at an intermediate (i.e. "serologic") level of resolution.
Hurley
C K
CK
Department of Oncology, Georgetown University Medical School, Washington, DC, USA. hurleyc@gunet.georgetown.edu
Steiner
N
N
Gans
C P
CP
Kosman
C
C
Mitton
W
W
Koester
R
R
Jones
P
P
Edson
S
S
Rizzuto
G
G
Hartzman
R J
RJ
Ng
J
J
Rodriguez-Marino
S G
SG
D000483:Alleles; D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D005091:Exons / Q000276:immunology; D005785:Gene Conversion / Q000276:immunology; D015235:HLA-B Antigens / Q000737:chemistry / Q000235:genetics*; D059910:HLA-B15 Antigen; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000276:immunology
D015235:HLA-B Antigens; D059910:HLA-B15 Antigen