Activity of ornithine decarboxylase in muscle of Japanese quail in hypergravity conditions.
Ornithine decarboxylase (ODC) is the rate limiting enzyme in the synthesis of polyamines which are generally required for animal cell proliferation.  Because of many different stimuli changing the activity of ODC, the effect of hypergravity on muscle ODC activity in Japanese quail was investigated.  Adult Japanese quail cockerels were exposed to 2G in the centrifuge permanently for 96 hours.  The activity of ODC was determined by radioisotopic method in supernatant of homogenised breast and fibular muscles (m. pectoralis minor, m.superficialis fibularis).  The activity of ODC was higher in breast muscle than in the fibular muscle in both, control and experimental groups.  Exposition of quail to hypergravity evokes approximately 2 fold increase of ODC activity in both breast and fibular muscles.  The results suggest that 96 hours of permanent hypergravitation (2G) caused activation of polyamine synthesis and their involvement in biochemical processes of adaptation to hypergravity.
Juráni
M
M
Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences, Ivanka pri Dunaji, Czech and Slovak Federal Republic.
Bod'a
K
K
Jankela
J
J
Jurániová
E
E
Sabo
V
V
D000222:Adaptation, Physiological; D000818:Animals; D002498:Centrifugation; D003370:Coturnix / Q000378:metabolism* / Q000502:physiology; D018471:Hypergravity; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism*; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D011073:Polyamines / Q000378:metabolism
D011073:Polyamines; D009955:Ornithine Decarboxylase