[Adjuvant analgesics in cancer pain: clinical pharmacology and efficacy].
The sequence of analgesic therapy for cancer pain should follow the WHO ladder regimen. Managing cancer pain with drug therapy provides the best results for the patients by using the combination of opioids, NSAIDs, and adjuvant analgesics. The selection or the combination of the drugs depends on the intensity, quality, and other characteristics of the pain. When the cancer pain is classified as neuropathic pain, we should use antidepressants, anticonvulsants, anxiolytics, or/and anti-arrhythmic drug.
Morimoto
M
M
Department of Anesthesiology, Kinki University School of Medicine.
D000701:Analgesics, Opioid / Q000627:therapeutic use*; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology*; D017410:Practice Guidelines as Topic; D014944:World Health Organization
D000701:Analgesics, Opioid; D014151:Anti-Anxiety Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000927:Anticonvulsants; D000928:Antidepressive Agents