[Hyper-IgE syndrome treated with interferon alpha 2 beta. Report of a case].
The hyper IgE syndrome is characterized by recurrent abscess on the skin, and airways and itching dermatitis. The data acquired in the lab is hypergammaglobulinemy, eosinophil in blood, tissue, sputum, with fagocitos, and quimiotaxis defect. Since 1972 it has been reported 150 cases in the world without no geographic difference and 2:1 relation with the masculine gender. The therapeutic ways are even controversial. The therapy with interferon alpha 2 beta is the alternative treatment so diminish the dermis inflammation as the seric IgE reduction. This case shows a patient with the classic clinic data and seric IgE levels who didn't present response to the habitual therapy, because of this. He was the switch to the interferon alpha 2 beta. Later on the therapy it wasesented clinical changes over the symptomatology with reduction in the over seric IgE.
Segura Mendez
N H
NH
Servicio de Alergia e Inmunología Clínica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS, Av. Cuauhtémoc 330 Col. Doctores 06725 México, DF.
del Rivero Hernández
L
L
Mejía Ortega
J
J
Ubaldo Ortiz Vázquez
J
J
Varela Delgado
A L
AL
Espínola Reyna
G
G
Rico
G
G
D000293:Adolescent; D006801:Humans; D006942:Hypergammaglobulinemia / Q000188:drug therapy*; D007073:Immunoglobulin E; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D011994:Recombinant Proteins; D013577:Syndrome
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D007073:Immunoglobulin E