title: Risk factors for hepatitis C virus infection among street youths.
abstract: BACKGROUND
  The relative contributions to risk of hepatitis C virus (HCV) infection resulting from unsafe sexual behaviours and exposures to blood (e.g., tattooing, body piercing and injection drug use) among youths at risk are not well known. We interviewed street youths about risk factors for HCV infection and documented their HCV antibody status.
  
  
  METHODS
  From December 1995 to September 1996 we recruited 437 youths aged 14 to 25 years who met specific criteria for itinerancy. Data on sociodemographic characteristics and lifetime risk factors were obtained during a structured interview, and a venous blood sample was taken for HCV antibody testing.
  
  
  RESULTS
  Many of the subjects reported behaviours that put them at risk for blood-borne diseases: 45.8% had injected drugs, 56.5% had at least 1 tattoo, and 78.3% had body piercing. The overall prevalence of HCV infection was 12.6% (95% confidence interval [CI] 9.7%-15.9%). In a multivariate logistic regression analysis, injecting drugs (adjusted odds ratio [OR] 28.4 [95% CI 6.6-121.4]), being over 18 years of age (adjusted OR 3.3 [95% CI 1.6-7.0]) and using crack cocaine (adjusted OR 2.3 [95% CI 1.0-5.3]) were independent risk factors for HCV infection. Having more than 1 tattoo (adjusted OR 1.8 [95% CI 0.95-3.6]) was marginally associated with HCV infection, and body piercing was not.
  
  
  CONCLUSIONS
  Drug injection was the factor most strongly associated with HCV infection among street youths. Given that injection drug users are the driving force of the HCV infection epidemic in Canada, increased intervention efforts to prevent initiation of drug injection are urgently needed to curb the epidemic.
authors.affiliation: Montreal Regional Public Health Department, McGill University, Montreal, Que. eroy@santepub-mtl.qc.ca
authors.forename: E
authors.initials: E
authors.lastname: Roy
authors.forename: N
authors.initials: N
authors.lastname: Haley
authors.forename: P
authors.initials: P
authors.lastname: Leclerc
authors.forename: J F
authors.initials: JF
authors.lastname: Boivin
authors.forename: L
authors.initials: L
authors.lastname: Cédras
authors.forename: J
authors.initials: J
authors.lastname: Vincelette
mesh_terms: D000293:Adolescent; D000328:Adult; D016009:Chi-Square Distribution; D005260:Female; D006526:Hepatitis C / Q000453:epidemiology* / Q000635:transmission; D018937:Hepatitis C Antibodies / Q000097:blood; D018453:Homeless Youth; D006801:Humans; D016015:Logistic Models; D008297:Male; D016485:Needle Sharing; D015995:Prevalence; D011677:Punctures; D011792:Quebec / Q000453:epidemiology; D012307:Risk Factors; D012725:Sexual Behavior; D015819:Substance Abuse, Intravenous; D011795:Surveys and Questionnaires; D013653:Tattooing
chemical_list: D018937:Hepatitis C Antibodies