Successful intraperitoneal nutrition in rabbits with short-bowel syndrome.
The efficacy of intraperitoneal alimentation as a means of nutritional support for various degrees of short-bowel syndrome was studied, using the rabbit model. Twenty-eight rabbits were divided into 5 groups. Group I had a sham operation; Groups II, III and IV had 50 %, 75 % and 90 % small-bowel resections (SBR), respectively; Group V had a 90 % SBR with intraperitoneal nutrition. All the rabbits received a regular diet and tap water post-operatively. The rabbits in Group V received intraperitoneal alimentation (IPA) by way of a peritoneal catheter inserted at the time of surgery. The nutrition consisted of 10 % dextrose with 5.5 % amino acids. This provided 30 - 35 kcal/kg of additional energy per day. All the rabbits within Group IV (90 % resection without IP nutrition) died within 2 to 5 weeks. IP nutrition enabled body weight to be maintained and prevented the death of all rabbits with 90 % small-bowel resection.
Erez
I
I
Department of Pediatric Surgery, Meir General Hospital, Kfar Saba, Israel. Ilan-ofi@shefayim.org.il
Gutermacher
M
M
Kariv
N
N
Bernheim
J
J
Freud
E
E
Bernheim
J
J
D000818:Animals; D001772:Blood Cell Count; D001835:Body Weight; D002408:Catheters, Indwelling; D004195:Disease Models, Animal; D008297:Male; D010288:Parenteral Nutrition; D011817:Rabbits; D012778:Short Bowel Syndrome / Q000097:blood / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate