title: Fructose metabolism by mature boar spermatozoa.
abstract: In 1945, Mann showed fructose to be the principal sugar in semen. For over half a century the means by which fructose is metabolized by sperm has been assumed to be by an initial phosphorylation catalysed by hexokinase, but this has never been substantiated. In the present study, by comparing the metabolism of glucose and fructose by both whole boar sperm and hypotonically treated cells, it is confirmed that fructose is phosphorylated by hexokinase to produce fructose 6-phosphate.
authors.affiliation: Department of Biochemistry, The University of Sydney, NSW, Australia. A.Jones@biochem.usyd.edu.au
authors.forename: A R
authors.initials: AR
authors.lastname: Jones
authors.forename: D E
authors.initials: DE
authors.lastname: Connor
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D005632:Fructose / Q000378:metabolism*; D005636:Fructosephosphates / Q000096:biosynthesis; D005947:Glucose / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism; D007038:Hypotonic Solutions; D066298:In Vitro Techniques; D008297:Male; D010766:Phosphorylation; D013094:Spermatozoa / Q000166:cytology / Q000378:metabolism*; D013552:Swine
chemical_list: D005636:Fructosephosphates; D007038:Hypotonic Solutions; D005632:Fructose; C027618:fructose-6-phosphate; D006593:Hexokinase; D005947:Glucose