Study of alkaloids from Adhatoda vasica Nees on their antiinflammatory activity.
Adhatoda vasica Nees is a shrub widespread throughout the tropical regions of southeast Asia. It possesses a wide spectrum of medicinal properties including positive effects on inflammatory diseases. The antiinflammatory activity of the methanol extract, the non-alkaloid fraction, the saponins and the alkaloids was evaluated by the modified hen's egg chorioallantoic membrane test. The alkaloid fraction showed potent activity at a dose of 50 microg/pellet equivalent to that of hydrocortisone while the MeOH extract and the other fractions showed less activity.
Chakraborty
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Institute of Pharmacognosy, Universitaetsplatz 4/1, A-8010 Graz, Austria.
Brantner
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AH
D000470:Alkaloids / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002642:Chick Embryo; D019684:Magnoliopsida / Q000737:chemistry*; D008515:Medicine, Ayurvedic; D010063:Ovum / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D012503:Saponins / Q000494:pharmacology
D000470:Alkaloids; D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D012503:Saponins