Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack.
The aphrodisiac effect of Eurycoma longifolia Jack (0.5 g/kg) was evaluated in noncopulator male rats using an electrical cage. Fractions of E. longifolia Jack decreased the hesitation time of noncopulator male rats, throughout the investigation period. Furthermore, it possessed a transient increase in the percentage of the male rats responding to the right choice, more than 50% of the male rats scored "right choice" after 3 weeks post-treatment and the effect became more prominent after 8 weeks post-treatment (only 40-50% of the control male rats responded to the right choice) using the electrical copulation cage. Hence, this study lends further support to the use of the plant by indigenous populations as a traditional medicine for its aphrodisiac property.
Ang
H H
HH
School of Pharmaceutical Sciences, University of Science Malaysia, Minden, 11800, Penang, Malaysia.
Ngai
T H
TH
D000818:Animals; D001046:Aphrodisiacs / Q000494:pharmacology*; D003307:Copulation / Q000187:drug effects* / Q000502:physiology; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005260:Female; D005900:Glaucarubin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D008297:Male; D028321:Plant Preparations / Q000494:pharmacology; D036702:Quassins; D051381:Rats; D017207:Rats, Sprague-Dawley
D001046:Aphrodisiacs; D028321:Plant Preparations; D036702:Quassins; C093532:eurycomanol; D005900:Glaucarubin