Magnetic resonance imaging and magnetic resonance spectroscopy in dementias.
This article reviews recent studies of magnetic resonance imaging and magnetic resonance spectroscopy in dementia, including Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, idiopathic Parkinson's disease, Huntington's disease, and vascular dementia. Magnetic resonance imaging and magnetic resonance spectroscopy can detect structural alteration and biochemical abnormalities in the brain of demented subjects and may help in the differential diagnosis and early detection of affected individuals, monitoring disease progression, and evaluation of therapeutic effect.
Hsu
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Magnetic Resonance Unit, Department of Veterans Affairs Medical Center, San Francisco 94121, USA.
Du
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Schuff
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Weiner
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MW
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis / Q000378:metabolism; D000679:Amygdala / Q000378:metabolism / Q000473:pathology; D001284:Atrophy / Q000378:metabolism / Q000473:pathology; D001921:Brain / Q000378:metabolism* / Q000473:pathology*; D003072:Cognition Disorders / Q000175:diagnosis; D003337:Corpus Callosum / Q000378:metabolism / Q000473:pathology; D003704:Dementia / Q000175:diagnosis* / Q000378:metabolism*; D015140:Dementia, Vascular / Q000175:diagnosis / Q000378:metabolism; D018728:Entorhinal Cortex / Q000378:metabolism / Q000473:pathology; D005625:Frontal Lobe / Q000378:metabolism / Q000473:pathology; D006624:Hippocampus / Q000378:metabolism / Q000473:pathology; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis / Q000378:metabolism; D016631:Lewy Bodies / Q000378:metabolism / Q000473:pathology; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D010300:Parkinson Disease / Q000175:diagnosis / Q000378:metabolism; D013702:Temporal Lobe / Q000378:metabolism / Q000473:pathology