title: New horizons in the regulation of bile acid and lipid homeostasis: critical role of the nuclear receptor FXR as an intracellular bile acid sensor.
authors.affiliation: Department of Gastroenterology, Catholic University of Chile School of Medicine, Santiago, Chile. marrese@med.puc.cl
authors.forename: M
authors.initials: M
authors.lastname: Arrese
authors.forename: S J
authors.initials: SJ
authors.lastname: Karpen
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D051017:Apoptosis Regulatory Proteins; D001647:Bile Acids and Salts / Q000378:metabolism*; D002352:Carrier Proteins / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology*; D050356:Lipid Metabolism; D008565:Membrane Proteins / Q000502:physiology*; D051379:Mice; D008815:Mice, Inbred Strains; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors / Q000502:physiology*; D000099150:Receptor, Farnesoid X-Activated
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D001647:Bile Acids and Salts; D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D008565:Membrane Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D000099150:Receptor, Farnesoid X-Activated; C406792:BFAR protein, human