Vasa homolog genes in mammalian germ cell development.
Many vasa homologue genes to Drosophila vasa have been isolated in various animal species. They provide specific molecular probes to analyze the establishment and the differentiation of germ cell lineage. In mammals, the expression of VASA protein becomes detectable in PGCs at the late migrating stage. Interestingly, during spermatogenesis the intracellular localization of VASA protein is closely associated with the chromatoid body.
Noce
T
T
Laboratory of Reproductive Biology, Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan. noce@libra.ls.m-kagaku.co.jp
Okamoto-Ito
S
S
Tsunekawa
N
N
D000595:Amino Acid Sequence; D000818:Animals; D053487:DEAD-box RNA Helicases; D005260:Female; D005854:Germ Cells / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D009866:Oogenesis / Q000235:genetics; D020365:RNA Helicases / Q000032:analysis / Q000235:genetics*; D051381:Rats; D017385:Sequence Homology; D013091:Spermatogenesis / Q000235:genetics
C498288:DDX4 protein, human; D053487:DEAD-box RNA Helicases; D020365:RNA Helicases