title: Biomedical program of the ALTAIR french russian flight onboard the MIR station.
abstract: One year after the achievement of the 2 weeks ANTARES french-russian mission in the MIR station in July 1992, a 22 days ALTAIR mission with a french cosmonaut has been performed in July 1993, making use of the scientific payload remaining on board. Taking benefit of the analysis of the previous mission, the experimental protocols were adapted to refine scientific objectives and gave to the scientists the opportunity to enhance quantitatively and qualitatively their results. The french biomedical program, conducted in close scientific cooperation with IMBP and associated laboratories, was composed of 8 experiments out of which 2 were new with regards to the ANTARES program. In the field of cardio-vascular physiology and fluid regulation, the experiments: ORTHOSTATISME, DIURESE have been renewed and complemented by the TISSU experiment (proposed by a german scientist) and a real-time tele-assistance program using US echography technic and ground support from the french CADMOS support control center located in Toulouse. With respect to neurosciences objectives, to the experiments VIMINAL (cognitive processes) and ILLUSIONS (study of proprioceptives cues), was added the SYNERGIES experiment to analyse the postural adjustments during movement. The IMMUNOLOGIE experiment carried on and the radiobiological experiment BIODOSE ended. Adding the results of the 2 missions ANTARES and ALTAIR, and the data obtained in between onboard with russian cosmonauts, the scientists have received a wealth of physiological data and gained reproducibility and confidence in their results.
authors.affiliation: CNES.
authors.forename: C
authors.initials: C
authors.lastname: Andre-Deshays
authors.forename: J P
authors.initials: JP
authors.lastname: Haignere
authors.forename: A
authors.initials: A
authors.lastname: Guell
authors.forename: O
authors.initials: O
authors.lastname: Marsal
authors.forename: L
authors.initials: L
authors.lastname: Suchet
authors.forename: A
authors.initials: A
authors.lastname: Kotovskaya
authors.forename: V
authors.initials: V
authors.lastname: Gratchev
authors.forename: A
authors.initials: A
authors.lastname: Noskin
authors.forename: A
authors.initials: A
authors.lastname: Grigoriev
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000337:Aerospace Medicine; D018493:Cardiovascular Deconditioning; D002320:Cardiovascular Physiological Phenomena; D003071:Cognition; D005602:France; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007111:Immunity, Cellular; D007391:International Cooperation; D008297:Male; D009068:Movement; D009949:Orientation; D012426:Russia; D013026:Space Flight; D017216:Telemedicine; D014893:Weightlessness