[Analysis of possibility of genotypic correlation between fear and anxiety].
Special features of anxious behavior in the elevated plus maze test and acoustic startle response were analyzed in 11 inbred mouse strains. A significant influence of the genotype both on the startle amplitude and behavior in the elevated plus maze was found. However, analysis of covariance did not reveal a genotype-related association between anxiety and startle amplitude. The data indicates that the fear-induced acoustic startle response and anxious behavior in the elevated plus maze (agoraphobia) are not genetically related.
Khrapova
M V
MV
Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk.
Popova
N K
NK
Avgustinovich
D F
DF
D000818:Animals; D001007:Anxiety / Q000235:genetics*; D005239:Fear; D005838:Genotype; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013216:Reflex, Startle / Q000235:genetics; D013045:Species Specificity