title: [Measurement of the common carotid arterial flow during parabolic flight in the anesthetized rat].
abstract: To measure the blood flow of a common carotid artery (CCA) during parabolic flight in the rat, we developed an animal double hold box (ADHB) made of styrene expanded form for the anesthetized rat to keep the animal at a proper posture in an aircaft. Twelve anesthetized rats weighing 291-342 g were surgically operated to mount a ultrasound flowmeter probe (1 mm size,1RS:Transonic Systems Inc.) around the right CCA and to insert a catheter into the right axillar artery for blood pressure measurement. These animals were held comfortably in ADHBs which were placed on the rack installed in the aircraft (MU-300). A total of 27 parabolic flights was performed and the blood flow was measured accurately in 9 rats. This special animal holding facility is useful for various types of animal experiments in an aircraft.
authors.affiliation: Department of Physiology, Fukushima Medical College.
authors.forename: M
authors.initials: M
authors.lastname: Yamasaki
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: T
authors.initials: T
authors.lastname: Nagayama
authors.forename: H
authors.initials: H
authors.lastname: Waki
authors.forename: H
authors.initials: H
authors.lastname: Wago
authors.forename: T
authors.initials: T
authors.lastname: Ohkouch
authors.forename: K
authors.initials: K
authors.lastname: Katahira
authors.forename: M
authors.initials: M
authors.lastname: Kaneko
authors.forename: K
authors.initials: K
authors.lastname: Torita
authors.forename: M
authors.initials: M
authors.lastname: Yamagata
authors.forename: K
authors.initials: K
authors.lastname: Shinnya
authors.forename: M
authors.initials: M
authors.lastname: Kanazawa
authors.forename: M
authors.initials: M
authors.lastname: Nemoto
authors.forename: H
authors.initials: H
authors.lastname: Mihara
authors.forename: S
authors.initials: S
authors.lastname: Ohkoshi
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: M
authors.initials: M
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Satoh
authors.forename: M
authors.initials: M
authors.lastname: Tan-no
authors.forename: S
authors.initials: S
authors.lastname: Nagaoka
authors.forename: C
authors.initials: C
authors.lastname: Mukai
authors.forename: M
authors.initials: M
authors.lastname: Uemura
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D017536:Carotid Artery, Common / Q000502:physiology*; D004867:Equipment Design; D006799:Housing, Animal; D018471:Hypergravity; D051381:Rats; D012039:Regional Blood Flow; D012212:Rheology / Q000295:instrumentation*; D013026:Space Flight / Q000295:instrumentation*; D014893:Weightlessness