title: Interaction of bacterial pathogens with polarized epithelium.
abstract: Many pathogens must surmount an epithelial cell barrier in order to establish an infection. While much has been learned about the interaction of bacterial pathogens with cultured epithelial cells, the influence of cell polarity on these events has only recently been appreciated. This review outlines bacterial-host epithelial cell interactions in the context of the distinct apical and basolateral surfaces of the polarized epithelium that lines the lumens of our organs.
authors.affiliation: Department of Medicine, University of California, San Francisco, California 94143-0654, USA. barbkaz@itsa.ucsf.edu
authors.forename: B I
authors.initials: BI
authors.lastname: Kazmierczak
authors.forename: K
authors.initials: K
authors.lastname: Mostov
authors.forename: J N
authors.initials: JN
authors.lastname: Engel
mesh_terms: D001419:Bacteria / Q000378:metabolism* / Q000472:pathogenicity; D016764:Cell Polarity; D004847:Epithelial Cells / Q000378:metabolism* / Q000382:microbiology; D014774:Virulence