title: Three new taxoids from the leaves of the Japanese yew, Taxus cuspidata.
abstract: Three new taxane diterpenoids were isolated from the leaves of the Japanese yew, Taxus cuspidta. Their structures were established as 5 alpha,13 alpha-diacetoxy-taxa-4(20),11-diene-9 alpha,10 beta-diol (1), 7 beta,13 alpha-diacetoxy-5 alpha-cinnamyloxy-2(3-->20)-abeo-taxa-4(20),11-diene-2 alpha,10 beta-diol (2), and 2 alpha,10 beta,13 alpha-triacetoxy-taxa-4(20),11-diene-5 alpha,7 beta,9 alpha-triol (3) respectively on the basis of 1D and 2D NMR data.
authors.affiliation: Laboratory of Applied Bioorganic Chemistry, Division of Life Science, Graduate School of Agricultural Science, Tohoku University, 1-1 Tsutsumidori-Amamiya, Aoba-ku, Sendai 981-8555, Japan.
authors.forename: Q W
authors.initials: QW
authors.lastname: Shi
authors.forename: T
authors.initials: T
authors.lastname: Oritani
authors.forename: H
authors.initials: H
authors.lastname: Kiyota
authors.forename: R
authors.initials: R
authors.lastname: Murakami
mesh_terms: D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D017239:Paclitaxel / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D043823:Taxoids; D014197:Trees / Q000737:chemistry*
chemical_list: C438454:2,10,13-triacetoxy-taxa-4(20),11-diene-5,7,9-triol; C438456:5,13 -diacetoxy-taxa-4(20),11-diene-9,10-diol; C438455:7,13-diacetoxy-5-cinnamyloxy-2(3-20)-abeo-taxa-4(20),11-diene-2,10-diol; D001952:Bridged-Ring Compounds; D004224:Diterpenes; D043823:Taxoids; D017239:Paclitaxel