[Effects of simulated weightlessness and overweight on the growth of osteoblast cultured in vitro].
A special rotator designed for this experiment was used to simulate the gravitational conditions. 3 groups of osteoblast cells were cultured under simulated hypogravity, normal (1 g) or hypergravity acceleratively (3 g) for 7 d. Changes of cell shape and speed of cell division were observed. The results showed that cells cultured under simulated hypogravity became round and cells divided slowly as compared with 1g group. While cells cultured under 3 g divided more actively and many growth spots appeared in the culture bottle.
Ding
B
B
Institute of Space Medico-Engineering, Beijing, China.
Wang
G
G
Zhang
X
X
Yue
M
M
Zeng
Y
Y
Tan
Y
Y
D055592:Biophysical Phenomena; D001703:Biophysics; D002455:Cell Division; D002478:Cells, Cultured; D018471:Hypergravity / Q000009:adverse effects; D010006:Osteoblasts / Q000166:cytology*; D012399:Rotation / Q000009:adverse effects*; D013997:Time Factors; D018474:Weightlessness Simulation