title: The suppressive effect of mangiferin with exercise on blood lipids in type 2 diabetes.
abstract: The effect of mangiferin (MF) with exercise on bood lipids was studied in KK-Ay mice, an animal model of type 2 diabetes. MF (30 mg/kg) reduced the blood cholesterol (p<0.05) and triglyceride level (p<0.01) of KK-Ay mice with exercise 2 weeks after oral administration when compared with the control group. Diabetes also often has elevated lipid levels. Therefore, it may be that MF has beneficial effects on hyperlipidemia in type 2 diabetes.
authors.affiliation: Department of Clinical Nutrition, Suzuka University of Medical Science, Mie, Japan. miura@suzuka-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Miura
authors.forename: N
authors.initials: N
authors.lastname: Iwamoto
authors.forename: M
authors.initials: M
authors.lastname: Kato
authors.forename: H
authors.initials: H
authors.lastname: Ichiki
authors.forename: M
authors.initials: M
authors.lastname: Kubo
authors.forename: Y
authors.initials: Y
authors.lastname: Komatsu
authors.forename: T
authors.initials: T
authors.lastname: Ishida
authors.forename: M
authors.initials: M
authors.lastname: Okada
authors.forename: K
authors.initials: K
authors.lastname: Tanigawa
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D008055:Lipids / Q000097:blood*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D005082:Physical Exertion / Q000502:physiology*; D014280:Triglycerides / Q000097:blood; D014966:Xanthenes / Q000494:pharmacology*; D044004:Xanthones
chemical_list: D007004:Hypoglycemic Agents; D000960:Hypolipidemic Agents; D008055:Lipids; D014280:Triglycerides; D014966:Xanthenes; D044004:Xanthones; C013592:mangiferin; D002784:Cholesterol