Postovulatory effect of intravenous administration of lipopolysaccharide (Escherichia coli, O55:B5) on the endocrine status of recently ovulated sows.
The effects of lipopolysaccharide (Escherichia coli, O55:B5), administered 18 h after ovulation in the second oestrus after weaning on the hormonal profiles in 14 Swedish cross-bred (Landrace x Yorkshire) multiparous sows were studied. The endotoxin group (E-group) sows were administered with 300 ng/kg of lipopolysaccharide (LPS) whereas the control group (C-group) sows were administered 5 ml of saline intravenously via an indwelling jugular cannula. Blood samples for hormonal analyses were collected from all sows until slaughter. In the E-group, progesterone, cortisol and prostaglandin F(2 alpha) metabolite levels increased significantly (p < 0.05) following LPS compared with the C-group. It can be concluded from this study that apart from elevating cortisol and prostaglandin F(2 alpha) metabolite, LPS also elevates progesterone levels.
Mwanza
A M
AM
Department of Obstetrics and Gynaecology, Swedish University of Agricultural Sciences, Centre for Reproductive Biology in Uppsala, Uppsala, Sweden. Affred.Malenga.Mwanza@og.slu.se
Madej
A
A
Kindahl
H
H
Lundeheim
N
N
Einarsson
S
S
D000818:Animals; D016022:Case-Control Studies; D015237:Dinoprost / Q000097:blood*; D004926:Escherichia coli; D004972:Estrus Detection; D005260:Female; D006854:Hydrocortisone / Q000097:blood*; D007275:Injections, Intravenous / Q000662:veterinary; D007700:Kinetics; D008070:Lipopolysaccharides / Q000494:pharmacology*; D010060:Ovulation / Q000502:physiology*; D011374:Progesterone / Q000097:blood*; D013552:Swine / Q000502:physiology*
D008070:Lipopolysaccharides; D011374:Progesterone; D015237:Dinoprost; D006854:Hydrocortisone