Two new polyhydroxysteroids from the gorgonian Isis hippuris.
Two new polyhydroxysteroids isihippurols A (1) and B (2) were isolated from the MeOH extract of the gorgonian Isis hippuris in addition to nine known steroids namely gorgosterol, 3alpha-acetoxy-24-methyl 11beta,18; 18,20beta; 22,25-triepoxy-5alpha-furostane, hippurin-1, 22-epi-hippuristanol, 22-epi-hippurin-1, 3-acetyl-2-deacetyl-22-epi-hippurin-1, 2-deacetylhippurin-1, 3beta, 7alpha, 11alpha-trihydroxygorgost-5-ene-12beta-acetate and 2-deacetyl-22-epi-hippurin-1. The structures of 1 and 2 have been determined as 1alpha, 3beta, 5alpha, 6beta, 11alpha-pentahydroxygorgosta-12beta-monoacetate and 1alpha, 3beta, 11alpha-trihydroxygorgosta-5alpha, 6alpha-epoxy-12beta-monoacetate respectively by spectral analysis and chemical correlation.
Shen
Y C
YC
Institute of Marine Resources, National Sun Yat-sen University, 70 Lien-Hai Road, 80424, R. O. C., Kaohsiung, Taiwan. ycshen@mail.nsysu.edu.tw
Prakash
C V
CV
Chang
Y T
YT
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003063:Cnidaria / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013261:Sterols / Q000737:chemistry* / Q000302:isolation & purification*
D013261:Sterols; C510125:hippuristanol; C438185:isihippurol A; C438186:isihippurol B; C040164:hippurin