New farnesylhydroquinone glycosides from the gorgonian Euplexaura anastomosans.
Euplexides F (3) and G (4), novel farnesylhydroquinone glycosides, have been isolated as minor constituents of the gorgonian Euplexaura anastomosans. The structures of these compounds have been determined by combined spectroscopic methods. These compounds exhibited moderate cytotoxicity and inhibitory activity against PLA2.
Seo
Y
Y
Marine Natural Products Laboratory, Korea Ocean Research & Development Institute, Ansan, P.O. Box 29, Seoul 425-600, Korea.
Rho
J R
JR
Cho
K W
KW
Shin
J
J
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D003063:Cnidaria / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D006873:Hydroquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020014:K562 Cells / Q000187:drug effects; D007723:Korea; D007951:Leukemia, Myeloid; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010741:Phospholipases A / Q000037:antagonists & inhibitors*; D054467:Phospholipases A2; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D006027:Glycosides; D006873:Hydroquinones; C445126:euplexide F; C445127:euplexide G; D010741:Phospholipases A; D054467:Phospholipases A2