Dynamics of blood pressure and pulse interval duration in rats after 14 day suspension.
At present, the pronounced changes in cardiovascular system observed in microgravity and on returning to 1 g are mostly attributed to the regulatory disturbances. The tail suspension model is used to simulate the effects of microgravity on muscle, bone and, on cardiovascular system of rats. Having in mind all limitations of this method, we decided to use it for analysis of the acute effects of cessation of tail suspension on regulation of cardiovascular system in rats.
Kharchenko
I
I
Space Biomedical Center for Training and Research, Moscow, Russia.
Tarasova
O
O
Borovik
A
A
Vinogradova
O
O
D000818:Animals; D017704:Baroreflex / Q000187:drug effects / Q000502:physiology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology*; D019417:Hindlimb Suspension; D009599:Nitroprusside / Q000494:pharmacology; D010656:Phenylephrine / Q000494:pharmacology; D011311:Pressoreceptors / Q000187:drug effects / Q000502:physiology*; D011674:Pulse; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000378:metabolism / Q000503:physiopathology; D014662:Vasoconstrictor Agents / Q000494:pharmacology; D014665:Vasodilator Agents / Q000494:pharmacology; D018474:Weightlessness Simulation
D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D009599:Nitroprusside; D010656:Phenylephrine