I-123 uptake by mediastinal goiter after recombinant human thyroid-stimulating hormone administration.
Radioiodine scintigraphy is useful to confirm the presence of mediastinal thyroid tissue. However, the degree of iodine avidity of mediastinal goiters varies. Recombinant human thyroid-stimulating hormone given to stimulate iodine uptake by thyroid remnants and thyroid cancer metastases can now replace thyroid hormone withdrawal scanning of selected patients who have well-differentiated thyroid carcinoma. A case of mediastinal goiter visualized with I-123 after the administration of recombinant human thyroid-stimulating hormone is reported.
Achong
D M
DM
Nuclear Medicine Service, James A. Haley Veterans' Hospital and University of South Florida College of Medicine, Tampa, Florida 33612, USA. dwight.achong@med.va.gov
Tenorio
L E
LE
D000368:Aged; D003937:Diagnosis, Differential; D006042:Goiter / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes / Q000493:pharmacokinetics; D008297:Male; D008477:Mediastinal Diseases / Q000000981:diagnostic imaging*; D013972:Thyrotropin; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
D007457:Iodine Radioisotopes; D013972:Thyrotropin