title: How should the minimum important difference for a health-related quality-of-life instrument be estimated?
authors.forename: G
authors.initials: G
authors.lastname: Samsa
mesh_terms: D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D012107:Research Design