title: Facile synthetic routes to all possible enantiomeric pairs of conduritol stereoisomers via efficient enzymatic resolution of conduritol B and C derivatives.
abstract: The first synthesis of all possible enantiomeric pairs of conduritol stereoisomers has been accomplished by efficient enzymatic resolution of conduritol B and C derivatives, followed by oxidation/reduction and the Mitsunobu reaction in stereo- and regioselective manners. Reaction: see text.
authors.affiliation: Department of Chemistry, Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790-784, South Korea.
authors.forename: Y U
authors.initials: YU
authors.lastname: Kwon
authors.forename: S K
authors.initials: SK
authors.lastname: Chung
mesh_terms: D003511:Cyclohexanols / Q000138:chemical synthesis* / Q000737:chemistry; D053138:Cyclohexenes; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors; D007700:Kinetics; D008049:Lipase / Q000378:metabolism*; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D003511:Cyclohexanols; D053138:Cyclohexenes; D004791:Enzyme Inhibitors; C090988:conduritol B; D008049:Lipase; D006026:Glycoside Hydrolases