title: [Primary angiosarcoma of the lung].
abstract: BACKGROUND
  Angiosarcomas are uncommon neoplasias, normally located in the skin, liver or heart. Primary angiosarcoma of the lung is rare.
  
  
  METHODS
  We report on a 41-year-old patient who presented increasing dyspnea. A 10-cm-angiosarcoma of the inferior lobe of the left lung was detected. After preoperative chemo- and radiotherapy the patient was referred to our clinic for surgical intervention. Resection of the inferior lobe of the lung, resection of part of the diaphragm, lymphadenectomy and replacement with a Vypro-II mesh was performed. Histological examination showed a mesenchymal neoplasia with myxoid tumor tissue, variable cell density and small proliferations of vessels. The immunohistochemical analysis confirmed the diagnosis of an angiosarcoma. The patient was discharged in a good general state for further ambulatory radiochemotherapy.
  
  
  CONCLUSIONS
  Angiosarcoma of the lung must always be included in the differential diagnosis of lung nodules and diffuse infiltrates despite its rare occurrence. Success with neoadjuvant therapy has been reported, but radical resection is recommended due to the cumulative bad prognosis.
authors.affiliation: Klinik für Chirurgie, RWTH Aachen. karsten.junge@post.rwth-aachen.de
authors.forename: K
authors.initials: K
authors.lastname: Junge
authors.forename: C
authors.initials: C
authors.lastname: Toens
authors.forename: C
authors.initials: C
authors.lastname: Peiper
authors.forename: B
authors.initials: B
authors.lastname: Hermanns
authors.forename: V
authors.initials: V
authors.lastname: Schumpelick
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D003964:Diaphragm / Q000473:pathology / Q000601:surgery; D006394:Hemangiosarcoma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D007124:Immunoenzyme Techniques; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D020360:Neoadjuvant Therapy; D011013:Pneumonectomy; D013526:Surgical Mesh
chemical_list: D014408:Biomarkers, Tumor