title: Principle approaches to selection of the short-arm centrifuge regimens for extended space flight.
abstract: Eight +Gz regimens on the SAC varying in their values (within 0.8 to 1.6 G), exposures, schedules, etc. were analyzed. Some regimens were combined with water-salt supplements (WSS) or veloergometer training (VE). Weightlessness was simulated by 3- to 28-day water immersion. +3 Gz loads on the centrifuge with the radius of 7.5 m were applied prior to and post immersion. Regimens for human runs on the SAC as a novel, perspective countermeasure for interplanetary expeditions should be selected with due regard of the human tolerance, their efficiency, and subsequent verification and specification in orbital flights.  These approaches showed that 3 days of exposure to 1.2 G combined with WSS and 6 days of exposure to G-loads from 0.8 to 1.6 G together with VE were most optimal.
authors.affiliation: Institute of Biomedical Problems, Moscow, Russia.
authors.forename: I F
authors.initials: IF
authors.lastname: Vil-Viliams
mesh_terms: D000054:Acceleration; D000337:Aerospace Medicine; D002498:Centrifugation / Q000295:instrumentation*; D015444:Exercise; D005081:Exercise Therapy; D005440:Fluid Therapy; D006801:Humans; D018471:Hypergravity; D007101:Immersion; D012965:Sodium Chloride / Q000627:therapeutic use; D013026:Space Flight; D014882:Water-Electrolyte Balance / Q000502:physiology; D018544:Weightlessness Countermeasures; D018474:Weightlessness Simulation
chemical_list: D012965:Sodium Chloride