title: Deacetylravidomycin M, a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326. II. Structure elucidation.
abstract: The structure of deacetylravidomycin M, an inhibitor of interleukin-4 signal transduction, was elucidated to be 6H-benzo[d]naphtho[1,2-b]pyran-6-one, 4-[3,6-dideoxy-3-(dimethylamino)-alpha-altropyranosyl]-1-hydroxy-10,12-dimethoxy-8-methyl- by spectroscopic studies including NMR measurements.
authors.affiliation: The Kitasato Institute, Kitasato University, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Arai
authors.forename: H
authors.initials: H
authors.lastname: Tomoda
authors.forename: N
authors.initials: N
authors.lastname: Tabata
authors.forename: N
authors.initials: N
authors.lastname: Ishiguro
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Omura
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D015847:Interleukin-4 / Q000037:antagonists & inhibitors; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015398:Signal Transduction / Q000187:drug effects; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C435068:deacetylravidomycin M; D015847:Interleukin-4; C049540:desacetylravidomycin