title: Results of ambulatory electrocardiography in overtly healthy Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy.
abstract: OBJECTIVE
  To determine results of ambulatory electrocardiography in and outcome of overtly healthy Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy.
  
  
  METHODS
  Case series.
  
  
  METHODS
  44 overtly healthy (25 male, 19 female) Doberman Pinschers.
  
  
  METHODS
  24-hour ambulatory electrocardiographic (Holter) recordings with > 90% scan quality obtained the same day that echocardiography was performed were reviewed.
  
  
  RESULTS
  Holter recordings from 42 of 44 (95%) dogs contained ventricular premature complexes (VPC). Fifteen of 44 (34%) dogs had > 100 VPC, 9 (20%) had > 500 VPC, and 5 (11%) had > 1,000 VPC. Nonsustained (< 30 seconds) ventricular tachycardia was detected in 4 dogs. Eighteen of 27 (67%) dogs with > 100 VPC, any couplets or triplets of VPC, or ventricular tachycardia developed dilated cardiomyopathy within 1 year, compared with 8 of 17 (47%) dogs with < 100 VPC, no couplets or triplets of VPC, and no ventricular tachycardia. Of the 18 dogs that did not develop dilated cardiomyopathy within 1 year, 11 (61%) did so within 3 years.
  
  
  CONCLUSIONS
  Results suggest that a high percentage of Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy will be found to have VPC during 24-hour ambulatory electrocardiography and that most will develop echocardiographic abnormalities indicative of cardiomyopathy.
authors.affiliation: Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Calvert
authors.forename: M
authors.initials: M
authors.lastname: Wall
mesh_terms: D000818:Animals; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000503:physiopathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004285:Dogs; D004452:Echocardiography / Q000662:veterinary; D015716:Electrocardiography, Ambulatory / Q000662:veterinary*; D005260:Female; D008297:Male; D018879:Ventricular Premature Complexes / Q000175:diagnosis / Q000503:physiopathology / Q000662:veterinary*