The ethylene signal transduction pathway in Arabidopsis.
The gaseous hormone ethylene is an important regulator of plant growth and development. Using a simple response of etiolated seedlings to ethylene as a genetic screen, genes involved in ethylene signal transduction have been identified in Arabidopsis. Analysis of two of these genes that have been cloned reveals that ethylene signalling involves a combination of a protein (ETR1) with similarity to bacterial histidine kinases and a protein (CTR1) with similarity to Raf-1, a protein kinase involved in multiple signalling cascades in eukaryotic cells. Several lines of investigation provide compelling evidence that ETR1 encodes an ethylene receptor. For the first time there is a glimpse of the molecular circuitry underlying the signal transduction pathway for a plant hormone.
Kieber
J J
JJ
Department of Biological Sciences, University of Illinois at Chicago 60607, USA. jkieber@uicvm.uic.edu
D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D027682:Cation Transport Proteins; D000079923:Copper Transporter 1; D005030:Ethylenes / Q000378:metabolism*; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D017343:Genes, Plant; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D009154:Mutation; D010937:Plant Growth Regulators / Q000378:metabolism; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D011494:Protein Kinases; D011956:Receptors, Cell Surface / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D015398:Signal Transduction / Q000235:genetics* / Q000502:physiology
C490078:CTR1 protein, S cerevisiae; D027682:Cation Transport Proteins; D000079923:Copper Transporter 1; D005030:Ethylenes; D005656:Fungal Proteins; D008565:Membrane Proteins; D010937:Plant Growth Regulators; D010940:Plant Proteins; D011956:Receptors, Cell Surface; D029701:Saccharomyces cerevisiae Proteins; C083750:ethylene receptors, plant; C036216:ethylene; D011494:Protein Kinases; C477753:CTR1 protein, Arabidopsis