title: 2'-O-modified oligoribonucleotides with terminal 3'-3'-internucleotide linkage and their derivatives.
abstract: A high RNA binding affinity and nuclease resistance of 2'-O-modified (2'-O-methyl, 2'-O-tetrahydropyranyl) oligoribonucleotides containing the "inverted" T at the 3'-end have been shown. The synthesis and properties of new photoactivatable perfluoroarylazide derivatives of these oligoribonucleotides are discussed.
authors.affiliation: Novosibirsk State University, ul. Pirogova 2, Novosibirsk 630090, Russia.
authors.forename: D
authors.initials: D
authors.lastname: Novopashina
authors.forename: M
authors.initials: M
authors.lastname: Kuznetsova
authors.forename: A
authors.initials: A
authors.lastname: Venyaminova
mesh_terms: D007700:Kinetics; D020320:Oligoribonucleotides, Antisense / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D010777:Photochemistry; D012313:RNA / Q000378:metabolism
chemical_list: D020320:Oligoribonucleotides, Antisense; D012313:RNA