title: Developmental testing of the Advanced Animal Habitat to determine compatibility with rats and mice.
abstract: The Research Animal Holding Facility (RAHF) and the Animal Enclosure Module (AEM) have housed rats during Space Shuttle flights since the 1980s, but the operational constraints of the hardware have limited the scientific return from these Shuttle flights.  The RAHF provides environmental control and monitoring for 24 rats with in-flight animal access, but it must be flown in the Spacelab.  Due to the infrequent availability of Spacelab flights, rodent experiments rely heavily on the AEM.  Unfortunately, the AEM supports only six rats, has no environmental control and provides no animal access in flight.  The Advanced Animal Habitat (AAH) is being developed to support up to 12 adult rats or 30 adult mice for up to 30 days, provide active temperature control, animal telemetry and on-orbit video, record environmental parameters in the animal cage, and provide in-flight animal access in the Middeck, the Spacelab or the Space Station.  To ensure the AAH can meet these requirements, animal testing is being conducted with rats and mice in every step of development.  Testing began with the cage configuration.
authors.affiliation: NASA Ames Research Center, Moffett Field, CA 94035, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Corbin
authors.forename: L A
authors.initials: LA
authors.lastname: Baer
authors.forename: R E
authors.initials: RE
authors.lastname: Grindeland
authors.forename: M
authors.initials: M
authors.lastname: Vasques
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D001835:Body Weight; D004326:Drinking; D004435:Eating; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D005260:Female; D006799:Housing, Animal / Q000592:standards*; D008099:Liver / Q000033:anatomy & histology; D008297:Male; D051379:Mice; D009929:Organ Size; D011156:Population Density; D051381:Rats; D017207:Rats, Sprague-Dawley; D018531:Spacecraft / Q000295:instrumentation; D013950:Thymus Gland / Q000033:anatomy & histology