[Alterations of nuclear maturity in spermatozoids of males with antecedents of cryptorchidism].
The association between infertility and cryptorchidism is an accepted fact, usually attributed to the oligozoosperm, asthenozoosperm or teratozoosperm presented in ejaculation products of males with this antecedent. The nuclear maturity in a sample of men with antecedents of cryptorchidism have been studied and these results have been compared to those of a control group. The results of this work show the deficient transformation of nuclear proteins to protamines in males with antecedents of cryptorchidism compared to the control group, due to the remaining of immature histones. Alterations of nuclear maturity able to contribute to the subfertility of these men were found in spermatozoids of adult males with antecedents of cryptorchidism.
Fernández Valadés
R
R
Servicio de Cirugía Pediátrica, Hospital Universitario Virgen de las Nieves.
Hortas Nieto
M L
ML
Castilla
J A
JA
López de la Torre Casares
M
M
Valladares Mendias
J C
JC
Alaminos Mingorance
M
M
Ruiz Montes
A
A
Castejón Casado
F J
FJ
Sánchez López-Tello
C
C
D003456:Cryptorchidism / Q000150:complications*; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D009687:Nuclear Proteins; D013094:Spermatozoa / Q000648:ultrastructure*
D009687:Nuclear Proteins