title: Research on Biolab, a multi-user facility for APM.
abstract: A study carried out by a team of seven scientists appointed by ESA resulted in the design of a biological laboratory "Biolab" for Columbus APM.  The basis for the study were four pre-Phase A studies performed by industry on the assumption that 15 racks would be available to biology and biotechnology in the APM.  Due to the constraints newly imposed by the Columbus project, only five racks are now allocated.  The tasks of the Biolab scientific team were:  (i) to define the scientific objectives of biological research in Columbus; (ii) to review the requirements of the industrial studies; and (iii) to design a multi-purpose facility compatible with the present constraints and satisfying the requirements of the biological investigations considered in the four studies.  The Biolab team was able to define a facility capable of accommodating in five racks the following biological objects:  small plants (up to 40 cm), insects like drosophila, frog eggs, single cells from animals, bacteria, slime molds and protozoa, as well as human physiology, but restricted to general diagnostic needs.  The Biolab facility includes instruments and devices providing the capacity of holding and/or growing the organisms as well as to perform basic experimentation and a minimum essential diagnostic inflight.  Within the growth unit the growth chambers/incubators are exchangeable, permitting the use of growth chambers of different sizes.  The temperature will be adjustable to the requirements of the objects under investigation, i.e. either 20 or 37 degrees C.  Thus a considerable level of flexibility will permit to investigate a broad spectrum of living systems.
authors.affiliation: Gruppe Weltraumbiologie, Institute of Biotechnology, ETH-Hönggerberg, Zürich, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Cogoli
authors.forename: A
authors.initials: A
authors.lastname: Cogoli
mesh_terms: D000818:Animals; D001001:Anura; D001690:Biological Science Disciplines; D002478:Cells, Cultured; D004780:Environment, Controlled; D004867:Equipment Design; D006801:Humans; D007313:Insecta; D007753:Laboratories; D010944:Plants; D012106:Research; D013026:Space Flight / Q000295:instrumentation*; D014893:Weightlessness