title: Photosensitized and catalytic oxidation of DNA by metallophthalocyanine-oligonucleotide conjugates.
abstract: The synthesis of new metallophthalocyanine-oligonucleotide conjugates is reported. These conjugates can cause sequence-specific photosensitized or catalytic oxidation of DNA by molecular oxygen.
authors.affiliation: Institute of Bioorganic Chemistry, Lavrentyev Ave. 8, Novosibirsk, 630090, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Koval
authors.forename: A A
authors.initials: AA
authors.lastname: Chernonosov
authors.forename: T V
authors.initials: TV
authors.lastname: Abramova
authors.forename: T M
authors.initials: TM
authors.lastname: Ivanova
authors.forename: O S
authors.initials: OS
authors.lastname: Fedorova
authors.forename: V M
authors.initials: VM
authors.lastname: Derkacheva
authors.forename: E A
authors.initials: EA
authors.lastname: Lukyanets
mesh_terms: D002384:Catalysis; D004247:DNA / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D054833:Isoindoles; D009841:Oligonucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D010777:Photochemistry; D011838:Radiation-Sensitizing Agents / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D007211:Indoles; D054833:Isoindoles; D009841:Oligonucleotides; D009942:Organometallic Compounds; D011838:Radiation-Sensitizing Agents; D004247:DNA; C013647:phthalocyanine