title: Eye development and the appearance and maintenance of corneal transparency.
abstract: Embryonic development of the eye, including the cornea, depends on the appearance and steady maintenance of intraocular pressure.  The eye is a gravity-sensitive organ, as evidence by changes in pupil diameter during parabolic flight.  The cornea is largely a paracrystal of extracellular matrix.  The extent to which it will polymerize normally in microgravity has yet to be determined.
authors.affiliation: Division of Biology, Kansas State University, Manhattan 66506, USA.
authors.forename: G W
authors.initials: GW
authors.lastname: Conrad
authors.forename: J L
authors.initials: JL
authors.lastname: Funderburgh
mesh_terms: D011508:Chondroitin Sulfate Proteoglycans / Q000032:analysis / Q000378:metabolism; D003315:Cornea / Q000737:chemistry / Q000196:embryology* / Q000294:innervation; D005314:Embryonic and Fetal Development / Q000502:physiology; D005109:Extracellular Matrix / Q000502:physiology; D005123:Eye / Q000737:chemistry / Q000196:embryology*; D018466:Gravity Sensing / Q000502:physiology*; D007429:Intraocular Pressure / Q000502:physiology*; D007632:Keratan Sulfate / Q000032:analysis / Q000378:metabolism; D000071234:Lumican; D009799:Ocular Physiological Phenomena; D011509:Proteoglycans / Q000032:analysis; D013026:Space Flight; D014893:Weightlessness
chemical_list: D011508:Chondroitin Sulfate Proteoglycans; D000071234:Lumican; D011509:Proteoglycans; D007632:Keratan Sulfate