Prebiotic transamination.
Biological amino acids and alpha keto acids directly condense with decarboxylation and transamination to yield product amino acids. This process is closely related to unusual amino acid decarboxylase enzymes in certain microorganisms and may represent a primordial mode of amino acid metabolism.
Bishop
J C
JC
Department of Chemistry, University of Tennessee at Chattanooga 37403, USA.
Cross
S D
SD
Waddell
T G
TG
D000409:Alanine / Q000378:metabolism; D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*; D019418:Evolution, Chemical; D018698:Glutamic Acid / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007651:Keto Acids / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*; D007656:Ketoglutaric Acids / Q000378:metabolism; D010649:Phenylalanine / Q000378:metabolism; D010667:Phenylpyruvic Acids / Q000378:metabolism; D019289:Pyruvic Acid / Q000378:metabolism; D000637:Transaminases / Q000737:chemistry*
D000596:Amino Acids; D007651:Keto Acids; D007656:Ketoglutaric Acids; D010667:Phenylpyruvic Acids; D018698:Glutamic Acid; D010649:Phenylalanine; D019289:Pyruvic Acid; D000637:Transaminases; D000409:Alanine; C031606:phenylpyruvic acid