Endometrial cancer: is surgical staging necessary?
Surgical staging has become the standard of care for the treatment of women with endometrial cancer. Recent scientific publications have confirmed the relative safety of this procedure when performed by subspecialty trained surgeons and have provided compelling evidence that the routine use of postoperative teletherapy is not cost effective, nor does it offer improved survival. New questions as to the safety and effectiveness of a laparoscopic staging approach have been answered in the affirmative. Although the extent of staging has not yet been defined, growing evidence suggests that preoperative studies and intraoperative clinical opinion cannot be consistently counted on to be predictive of postoperative histologic status. Therefore, all patients should be considered at risk and should undergo an operation in a clinical situation that offers the immediate availability of retroperitoneal staging or cytoreductive surgery if necessary.
Orr
J W
JW
Florida Gynecologic Oncology, Lee Cancer Care, Fort Myers, Florida 33901, USA. james.orr@leememorial.org
Roland
P Y
PY
Leichter
D
D
Orr
P F
PF
D002986:Clinical Trials as Topic; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods*; D007813:Laparotomy; D008197:Lymph Node Excision; D009367:Neoplasm Staging / Q000379:methods*; D018579:Patient Selection; D011300:Preoperative Care; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012187:Retroperitoneal Space / Q000473:pathology / Q000601:surgery; D012307:Risk Factors