title: [Can acute disseminated encephalomyelitis progress in a deferred way?].
abstract: OBJECTIVE
  To report on the heterogeneity with regard to the clinical course of the acute disseminated encephalomyelitis (ADEM).
  
  
  METHODS
  A 5 year old boy suffered of acute disseminated encephalomyelitis of unknown origin. This child suffered two episodes of different neurologic symptoms separated by several weeks. Based on the clinical manifestations and typical appearance of magnetic resonance imaging findings and the absence of oligoclonal bands in CSF immunoglobulins, multiple sclerosis (MS) was ruled out.
  
  
  CONCLUSIONS
  We postulate that the recurrent symptoms in our patient could be explained as a multiphasic disseminated encephalomyelitis (MDEM). Favourable outcome after simultaneous treatment with methylprednisolone and intravenous immunoglobulin is emphasized in this report.
authors.affiliation: Hospital de Cruces, Baracaldo, 48903, España.
authors.forename: B
authors.initials: B
authors.lastname: Gener
authors.forename: C
authors.initials: C
authors.lastname: Garaizar-Axpe
authors.forename: C
authors.initials: C
authors.lastname: Ruiz Espinosa
authors.forename: J M
authors.initials: JM
authors.lastname: Prats-Viñas
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003244:Consciousness Disorders / Q000209:etiology; D003937:Diagnosis, Differential; D018450:Disease Progression; D004673:Encephalomyelitis, Acute Disseminated / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology / Q000473:pathology / Q000628:therapy; D006261:Headache / Q000209:etiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008218:Lymphocytosis / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008590:Meningoencephalitis / Q000150:complications / Q000276:immunology; D008775:Methylprednisolone / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000175:diagnosis; D012008:Recurrence; D014839:Vomiting / Q000209:etiology
chemical_list: D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D008775:Methylprednisolone