Extent and distribution of vascular brain injury in pediatric road fatalities.
This study used a multidisciplinary approach to examine the brains of pediatric road trauma fatalities in the Sydney area over a 3-year period. The brains of 32 children (0-16 years) were examined: 20 pedestrians, nine passengers, and three cyclists. The extent and distribution of brain injury was assessed, peak linear head acceleration determined, and the severity of brain damage was compared to that previously reported for adults using the same scoring method. Skull fractures (20/32) and subarachnoid haemorrhage (22/32) were the commonest head injuries. In general, the neuropathology was similar to that seen in adults, with a high percentage of damage in the corpus callosum and gliding contusions within the subcortical white matter. Intracerebral hemorrhage was relatively rare. For frontal and occipital head impacts, the corpus callosum was the most injured part of the brain, followed by the deep central structures and the temporal lobes, whereas for lateral impacts, the injuries were more evenly distributed. Comparison of the current data for children with the vascular injury sector scores reported for adults suggests that the brains of children are more severely damaged for the same peak linear head acceleration.
Gorrie
C
C
Neural Injury Research Unit, School of Anatomy, University of New South Wales, Sydney, Australia. c.gorrie@unsw.edu.au
Duflou
J
J
Brown
J
J
Gibson
T
T
Waite
P M
PM
D000054:Acceleration; D000063:Accidents, Traffic; D000293:Adolescent; D000367:Age Factors; D001921:Brain / Q000473:pathology*; D020202:Cerebral Hemorrhage, Traumatic / Q000401:mortality / Q000473:pathology; D020214:Cerebrovascular Trauma / Q000401:mortality* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009517:New South Wales / Q000453:epidemiology; D012887:Skull Fractures / Q000401:mortality / Q000473:pathology; D015599:Trauma Severity Indices