title: Risk factors for development of status epilepticus in dogs with idiopathic epilepsy and effects of status epilepticus on outcome and survival time: 32 cases (1990-1996).
abstract: OBJECTIVE
  To identify risk factors for episodes of status epilepticus (SE) in dogs with idiopathic epilepsy and determine how SE affects long-term outcome and survival time.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  32 dogs with idiopathic epilepsy.
  
  
  METHODS
  Information on signalment, seizure onset, initiation of treatment, anticonvulsants administered, number of episodes of SE, overall seizure control, and long-term outcome was obtained from medical records and through telephone interviews. Differences between dogs that did and did not have episodes of SE were evaluated statistically.
  
  
  RESULTS
  19 (59%) dogs had 1 or more episodes of SE. Body weight was the only variable significantly different between dogs that did and did not have episodes of SE. Thirteen dogs (9 that did not have episodes of SE and 4 that did) were still alive at the time of the study and were > or = 10 years old. Six of the 19 (32%) dogs that had episodes of SE died of causes directly attributed to the seizure disorder. Mean life spans of dogs that did and did not have episodes of SE were 8.3 and 11.3 years, respectively. Survival time was significantly different between groups.
  
  
  CONCLUSIONS
  Results suggest that a substantial percentage of dogs with idiopathic epilepsy will have episodes of SE. Dogs with greater body weights were more likely to have episodes of SE, and early appropriate seizure treatment did not appear to decrease the risk that dogs would have episodes. Most dogs with idiopathic epilepsy had an expected life span, but survival time was shorter for dogs that had episodes of SE.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA.
authors.forename: M
authors.initials: M
authors.lastname: Saito
authors.forename: K R
authors.initials: KR
authors.lastname: Muñana
authors.forename: N J
authors.initials: NJ
authors.lastname: Sharp
authors.forename: N J
authors.initials: NJ
authors.lastname: Olby
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use; D001835:Body Weight; D004283:Dog Diseases / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality; D004285:Dogs; D004827:Epilepsy / Q000150:complications / Q000401:mortality / Q000662:veterinary; D005260:Female; D008297:Male; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D012307:Risk Factors; D012640:Seizures / Q000150:complications / Q000401:mortality / Q000662:veterinary; D013226:Status Epilepticus / Q000209:etiology / Q000401:mortality / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants