Long-term follow-up of neurosarcoidosis.
The authors evaluated the long-term clinical outcome of neurosarcoidosis and determined predictive factors of disease course. Twenty-seven patients with neurosarcoidosis were followed for at least 5 years from the onset of neurologic symptoms. Patients with CNS involvement during the course of the disease had a higher Modified Oxford Handicap Scale score than those with peripheral nervous system involvement (p < 0.02). CNS involvement may be a predictive factor for a less favorable disease course. Early and intensive treatment should be considered in such cases.
Ferriby
D
D
Department of Neurology, CHRU de Lille, France. d-ferriby@chru-lille.fr
de Seze
J
J
Stojkovic
T
T
Hachulla
E
E
Wallaert
B
B
Destée
A
A
Hatron
P Y
PY
Vermersch
P
P
D000293:Adolescent; D000328:Adult; D002493:Central Nervous System Diseases / Q000401:mortality / Q000628:therapy; D016009:Chi-Square Distribution; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012507:Sarcoidosis / Q000401:mortality / Q000628:therapy; D018709:Statistics, Nonparametric