title: [Analysis of survival and mortality curves with the model of vital receptors. The maximal life span. Effect of temperature on the life span. The mortality probability density function (mortality curve) and its parameters].
abstract: We have continued an analysis of survival curves by the model of the vital receptors (MVR). The main types survival function (E-, TW- and GM-distributions) have been considered. It was found that the maximal life span depends on the threshold concentration of vital receptors. Equations are obtained for the dependence of the maximal life span on the kinetic parameters in the reactions of inactivation, destruction and inactivation. Dependence of maximal time life on initial size of the population have been considered. The influence of temperature on the survival curves is analysed by E-distribution. Equations are founded for the description of thermosurvival and thermoinactivation curves. Equation are obtained for the dependence of density function and it characteristics (modal and antimodal age, coefficient of asymmetry) on the MVR parameters. It was shown that E-, TW- and GM-distribution has different types of asymmetry. The coefficient of asymmetry of GM-distribution is associated on the MVR parameters. It is assumed that symmetry of the curves of mortality and birth-rate is coordinated by the mechanisms of MVR.
authors.affiliation: N. N. Semenov Institute of Chemical Physics, Russian Academy of Science, Kosygin str. 4, Moscow 117977, Russia. poltorakov@mtu-net.ru
authors.forename: A P
authors.initials: AP
authors.lastname: Poltorakov
mesh_terms: D000465:Algorithms; D000818:Animals; D004247:DNA; D008017:Life Expectancy; D008954:Models, Biological; D009026:Mortality; D011336:Probability
chemical_list: D004247:DNA