Novel gene cassettes and integrons.
An increase in multiresistant Enterobacteriaceae was observed at one of the departments of the University Medical Center Utrecht. Nine different integrons and 17 gene cassettes were found, including the new gene cassette aadA8. This cassette was highly related to aadA3 and aadA2. In addition, an unknown promoter sequence was found for two integrons.
Peters
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ED
Eijkman-Winkler Institute, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands.
Leverstein-van Hall
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MA
Box
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AT
Verhoef
J
J
Fluit
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AC
D001426:Bacterial Proteins / Q000235:genetics*; D001483:Base Sequence; D004269:DNA, Bacterial / Q000032:analysis; D004755:Enterobacteriaceae / Q000235:genetics*; D019426:Integrases / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family; D009713:Nucleotidyltransferases / Q000737:chemistry / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D019426:Integrases; D009713:Nucleotidyltransferases; C439350:aadA8 protein, Enterobacter aerogenes; C115006:integron integrase IntI1; C020565:gentamicin 2''-nucleotidyltransferase