title: Asymmetric synthesis of carbocyclic pyrimidine nucleosides via pi-allylpalladium complex.
abstract: Racemic and enantiomerically pure carbocyclic pyrimidine nucleosides were synthesized efficiently by a convergent approach using Trost nucleophilic addition of pi-allylpalladium complexes.
authors.affiliation: Pharmasset, Inc., Tucker, Georgia 30084, USA.
authors.forename: J
authors.initials: J
authors.lastname: Shi
authors.forename: R F
authors.initials: RF
authors.lastname: Schinazi
mesh_terms: D000498:Allyl Compounds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D000498:Allyl Compounds; D009942:Organometallic Compounds; D011741:Pyrimidine Nucleosides; D010165:Palladium