title: Amino acids of the Murchison meteorite.  III.  Seven carbon acyclic primary alpha-amino alkanoic acids.
abstract: All of the eighteen possible seven-carbon acyclic primary alpha-amino alkanoic acids have been positively identified in a hot-water extract of the Murchison meteorite by the combined use of gas chromatography-mass spectrometry, ion exchange chromatography and reversed-phase chromatography.  None of these amino acids has previously been found in meteorites or in any other natural material.  They range in concentration from < or = 0.5 to 5.3 nmol g-1.  Configuration assignments were made for 2-amino-3,4-dimethylpentanoic acid and allo-2-amino-3,4-dimethylpenatonoic acid and the diasteromer ratio was determined.  Fifty-five amino acids have now been positively identified in the Murchison meteorite, 36 of which are unknown in terrestrial materials.  This unique suite of amino acids is characterized by the occurrence of all structural isomers within the two major classes of amino acids represented, by the predominance of branched chain isomers, and by an exponential decline in amount with increasing carbon chain length within homologous series.  These characteristics of the Murchison amino acids are suggestive of synthesis before incorporation into a parent body.
authors.affiliation: Department of Chemistry, Arizona State University, Tempe 85287, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Cronin
authors.forename: S
authors.initials: S
authors.lastname: Pizzarello
mesh_terms: D000596:Amino Acids / Q000032:analysis*; D002244:Carbon / Q000032:analysis*; D002852:Chromatography, Ion Exchange; D019418:Evolution, Chemical; D008401:Gas Chromatography-Mass Spectrometry; D006838:Hydrocarbons / Q000032:analysis*; D007536:Isomerism; D019110:Meteoroids
chemical_list: D000596:Amino Acids; D006838:Hydrocarbons; D002244:Carbon