title: [A digital simulation study on the effect of change in cardiovascular system parameters on the pulse waveform of the radial artery].
abstract: OBJECTIVE
  To understand the effect of the change in cardiovascular system parameters on the pressure pulse waveform of the radial artery.
  
  
  METHODS
  A previously developed cardiovascular system mathematical model was used in this simulation study. The parameters used were heart rate, ventricular contractility, arterial compliance, peripheral resistance and blood viscosity.
  
  
  RESULTS
  The change in each parameter would influence the pulse waveform. Most of the influences were in agreement with the results of clinical observations reported in the literature. However, several new phenomena were observed. The effect of change in single parameter on the pulse waveform was different for different combinations of other parameter values.
  
  
  CONCLUSIONS
  It is suggested that the model is useful in studying the relationship between cardiovascular system parameters and pulse waveform of the radial artery.
authors.affiliation: Institute of Space Medico-Engineering, Beijing, China.
authors.forename: A
authors.initials: A
authors.lastname: Kong
authors.forename: J
authors.initials: J
authors.lastname: Bai
authors.forename: B S
authors.initials: BS
authors.lastname: Xi
authors.forename: P Z
authors.initials: PZ
authors.lastname: Zu
authors.forename: J P
authors.initials: JP
authors.lastname: Zhang
mesh_terms: D000337:Aerospace Medicine; D001809:Blood Viscosity; D002320:Cardiovascular Physiological Phenomena; D003187:Compliance; D003198:Computer Simulation; D006339:Heart Rate; D006801:Humans; D008955:Models, Cardiovascular; D009200:Myocardial Contraction; D011674:Pulse; D017534:Radial Artery / Q000502:physiology*; D014655:Vascular Resistance