title: [25-year development of the theory of functional systems at P K Anokhin Institute of Normal Physiology and the Department of Normal Physiology of I M Sechenov Moscow Medical Academy].
abstract: New trends in the development of the theory of functional systems proposed by P.K. Anokhin in the scientific complex P.K. Anokhin Institute--Department of Normal Physiology during the last twenty five years are regarded. It has been shown that the functional systems represent an objective reality. Holographic and informational properties of the functional systems and general principles of their interrelations in the whole organism i.e. hierarchic domination, multiparametric and successive interaction have been disclosed. Some notions about "systemo-quanta" of vital activity as discrete units of dynamic activity of functional systems have been formulated. Further developments in the systemogenesis of behavioral acts also are presented. New ideas about pacemaker mechanism of dominant biological motivations, the role of oligopeptides in the system organization of behavioral acts have been formulated. The role of early genes in formation of behavioral reactions of animals and in the mechanisms of emotional stress is shown. The role of some oligopeptides in the mechanisms of resistance to emotional stress is stated. Some devices modeling the properties of functional systems and able to assess different organism's functional systems have been developed. Practical application of the theory of functional systems is also shown in the paper.
authors.affiliation: P.K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences.
authors.forename: K V
authors.initials: KV
authors.lastname: Sudakov
mesh_terms: D000047:Academies and Institutes / Q000266:history*; D001921:Brain / Q000502:physiology; D004644:Emotions; D049672:History, 19th Century; D049673:History, 20th Century; D010827:Physiology / Q000266:history*; D012426:Russia; D014586:USSR; D014495:Universities / Q000266:history*