[Coxsackie B viral infection in the etiology and clinical pathogenesis of psoriasis].
The data submitted point to the importance of the enteroviral infection, in particular, Coxsackie' B vira in the pathogenesis of many non-infectious diseases. Our studies explore the possibility for the Coxsackie B virus involvement in the etiopathogenesis of psoriasis. 25 examined patients with psoriasis revealed in 100% of cases antibodies to the Coxsackie B virus in diagnostic titres, with a number of patients having displayed a progressive increase in the titres of the above antibodies, which fact suggest to us that there may be an association between psoriasis and Coxsackie' B vira. The major proportion of seropositive psoriatic patients (88%) have been found to have antibodies to association of two, three or four Coxsackie' B vira, which fact can be taken as further evidence for their etiopathogenic part in the development of dermatosis. Antibodies to Coxsackie B1 and B5 virus have been shown to occur more frequently among seropositive patients, this underlying their particular importance in the development of psoriasis.
Korzhova
T P
TP
Shyrobokov
V P
VP
Koliadenko
V H
VH
Korniushenko
O M
OM
Akhramieieva
N V
NV
Stepanenko
V I
VI
D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology; D015331:Cohort Studies; D003384:Coxsackievirus Infections / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D029822:Enterovirus B, Human / Q000276:immunology / Q000472:pathogenicity*; D005260:Female; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000209:etiology* / Q000276:immunology / Q000473:pathology*; D012698:Serologic Tests
D000914:Antibodies, Viral