title: Simultaneous acquisition of multiple resolution images for dynamic contrast enhanced imaging of the breast.
abstract: An imaging technique is described that allows the reconstruction of a series of images at high temporal rates, while simultaneously providing images at high spatial resolution. The method allows one to arbitrarily choose from among several combinations of temporal/spatial resolutions during postprocessing. This flexibility is accomplished by strategically interleaving multiple undersampled projection reconstruction datasets (or subapertures), in which each set can be used to reconstruct a high temporal resolution image. Images with increasingly higher spatial resolutions can subsequently be formed by combining two or more subaperture datasets. The technique is demonstrated in vivo to assess the kinetics of contrast enhancement and to visualize the architectural features of suspicious breast lesions.
authors.affiliation: Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA. hsong@oasis.rad.upenn.edu
authors.forename: H K
authors.initials: HK
authors.lastname: Song
authors.forename: L
authors.initials: L
authors.lastname: Dougherty
authors.forename: M D
authors.initials: MD
authors.lastname: Schnall
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D012680:Sensitivity and Specificity