title: Drug sensitivity of Candida yeast isolated from patients with allergic diseases.
abstract: Viability of 40 Candida spp. cultures was studied after long-term exposure to antifungal drugs in minimum inhibitory concentrations. The fungicidal effect decreased in the series: pimafucin-nitrofungin-diflucan-orungal-levorine-clotrimazole-exoderil. Nizoral in a concentration of 4 microg/ml was ineffective; in the rest cultures the effect was either fungistatic (of different degree) or null. Pimafucin, diflucan, nitrofungin, orungal, levorine, and exoderil possessed individual fungicidal effects.
authors.affiliation: I. I. Metchnikov Institute of Vaccines and Sera, Russian Academy of Medical Sciences, Moscow. veraar@mail.ru
authors.forename: V G
authors.initials: VG
authors.lastname: Arzumanyan
authors.forename: B F
authors.initials: BF
authors.lastname: Semenov
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002174:Candicidin / Q000494:pharmacology; D002175:Candida / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology; D003022:Clotrimazole / Q000494:pharmacology; D015725:Fluconazole / Q000494:pharmacology; D006801:Humans; D006967:Hypersensitivity / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D009596:Nitrophenols / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D009596:Nitrophenols; D002174:Candicidin; C002722:nitrofungin; D015725:Fluconazole; D003022:Clotrimazole