Drug sensitivity of Candida yeast isolated from patients with allergic diseases.
Viability of 40 Candida spp. cultures was studied after long-term exposure to antifungal drugs in minimum inhibitory concentrations. The fungicidal effect decreased in the series: pimafucin-nitrofungin-diflucan-orungal-levorine-clotrimazole-exoderil. Nizoral in a concentration of 4 microg/ml was ineffective; in the rest cultures the effect was either fungistatic (of different degree) or null. Pimafucin, diflucan, nitrofungin, orungal, levorine, and exoderil possessed individual fungicidal effects.
Arzumanyan
V G
VG
I. I. Metchnikov Institute of Vaccines and Sera, Russian Academy of Medical Sciences, Moscow. veraar@mail.ru
Semenov
B F
BF
D000935:Antifungal Agents / Q000494:pharmacology*; D002174:Candicidin / Q000494:pharmacology; D002175:Candida / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology; D003022:Clotrimazole / Q000494:pharmacology; D015725:Fluconazole / Q000494:pharmacology; D006801:Humans; D006967:Hypersensitivity / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D009596:Nitrophenols / Q000494:pharmacology
D000935:Antifungal Agents; D009596:Nitrophenols; D002174:Candicidin; C002722:nitrofungin; D015725:Fluconazole; D003022:Clotrimazole