Design and synthesis of novel fluorocyclopropanoid nucleosides.
Novel fluorocyclopropanoid nucleosides were designed, synthesized and evaluated their antiviral activities against poliovirus, HSV, HIV, and HBV.
Lee
Y R
YR
College of Pharmacy, Sookmyung Women's University, Seoul 140-742, Korea.
Park
J H
JH
Jeon
R
R
Jeong
L S
LS
Chun
M W
MW
Kim
H D
HD
D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000494:pharmacology*; D015195:Drug Design; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009705:Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology*
D000998:Antiviral Agents; D003521:Cyclopropanes; D006845:Hydrocarbons, Fluorinated; D009705:Nucleosides