title: Neurosciences research in space:  future directions.
abstract: Future research in the neurosciences can best be understood in the context of NASA's life sciences goals in the near term (1990-95), mid term (1995-2000), and long term (2000 and beyond).  Since NASA is planning short-duration Spacelab and International Microgravity Laboratory (IML) flights for many years to come, the acute effects of exposure to microgravity will continue to be of experimental and operational interest in the near term.  To this end, major new areas of research will be devoted to ground-based studies of preflight adaptation trainers and their efficacy in preventing or reducing the incidence of space motion sickness.  In addition, an extensive series of studies of the vestibular system will be conducted inflight on the IML-1 mission   The IML-2 mission will emphasize behavior and performance, biological rhythms, and further vestibular studies.  In the mid-term period, Spacelab missions will employ new technology such as magnetic recording techniques in order to evaluate changes in the processing of sensory and motor inputs at the brainstem and cortical level during exposure to microgravity.  Two Space Life Sciences (SLS) missions planned for the mid to late 1990's, SLS-4 and SLS-5, will utilize an onboard centrifuge facility that will enable investigators to study the effects of partial gravity on sensory and motor function.  In the long term (2000 and beyond), Space Station Freedom and long-duration missions will provide opportunities to explore new options in the neurosciences, such as sensory substitution and augmentation, through the use of physical sensors to provide three-dimensional tactile-visual, tactile-auditory and tactile-somatosensory inputs.  The use of this technology will be extremely important in the area of robotic telepresence.  Finally, Space Station Freedom and proposed LifeSat missions will provide neuroscientists the opportunity to study the effects of partial gravity and microgravity on neuronal plasticity.
authors.affiliation: Space Medicine and Biology Branch, NASA Headquarters, Washington, DC.
authors.forename: F M
authors.initials: FM
authors.lastname: Sulzman
authors.forename: J W
authors.initials: JW
authors.lastname: Wolfe
mesh_terms: D002498:Centrifugation; D005544:Forecasting; D006801:Humans; D009462:Neurology / Q000639:trends*; D009473:Neuronal Plasticity; D012107:Research Design; D013026:Space Flight / Q000295:instrumentation* / Q000639:trends*; D018489:Space Motion Sickness; D014481:United States; D018557:United States National Aeronautics and Space Administration; D015837:Vestibular Diseases / Q000209:etiology / Q000503:physiopathology; D014893:Weightlessness / Q000009:adverse effects