[Verrucarin A from conidia of Dendrodochium toxicum Pidopl. et Bilai].
A substance which was dyed blue by 4p-(nitrobenzyl)pyridine, that evidenced for its trichotecene nature, has been isolated in the crystalline form from conidia Dendrodochium toxicum Pidopl. et Bilai--roridine H producer. Thin-layer chromatography of the substance in three different systems, the well-known macrocyclic trichotecenes being used as standards, permitted it to be identified with verrucarine A. The substances possessed high biological activity with respect to the indicator test-culture Candida kefyr 900. No other compounds of trichotecene nature were found. Possible role of verrucarine A is discussed.
Rubezhniak
I G
IG
Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154 Zabolotny St., Kyiv, 03143, Ukraine.
D002855:Chromatography, Thin Layer; D003460:Crystallization; D003904:Mitosporic Fungi / Q000737:chemistry*; D013172:Spores, Fungal / Q000737:chemistry; D014255:Trichothecenes / Q000737:chemistry* / Q000302:isolation & purification
D014255:Trichothecenes; C005348:muconomycin A