title: Abnormal coagulation in the postoperative period contributing to excessive bleeding.
abstract: This article deals primarily with acquired disorders that disrupt normal hemostasis and cause excessive bleeding in the postoperative period because of the coagulopathy itself or because of drugs needed to treat the hemostatic disorder.
authors.affiliation: Department of Medicine, Division of Hematology, Hemophilia Center, Special Hematology and Hemostasis Laboratory, Cardeza Foundation for Hematologic Research, Thomas Jefferson University Hospital and Medical Center, Philadelphia, Pennsylvania, USA.
authors.forename: R
authors.initials: R
authors.lastname: McKenna
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects / Q000494:pharmacology; D001241:Aspirin / Q000494:pharmacology; D001777:Blood Coagulation / Q000187:drug effects; D001778:Blood Coagulation Disorders / Q000150:complications* / Q000628:therapy; D001803:Blood Transfusion; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D004730:Endothelium, Vascular / Q000502:physiology; D005169:Factor VIII / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D005343:Fibrinolytic Agents / Q000494:pharmacology; D006470:Hemorrhage / Q000209:etiology; D006488:Hemostasis, Surgical; D006493:Heparin / Q000009:adverse effects; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects; D006801:Humans; D008107:Liver Diseases / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D011183:Postoperative Complications / Q000209:etiology*; D011468:Prostatectomy / Q000009:adverse effects; D013917:Thrombin / Q000502:physiology; D013921:Thrombocytopenia / Q000139:chemically induced / Q000503:physiopathology; D014813:Vitamin K Deficiency / Q000150:complications
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D010975:Platelet Aggregation Inhibitors; D005169:Factor VIII; D006493:Heparin; D013917:Thrombin; D001241:Aspirin