[Supramolecular regulation of the activity of some oxidoreductases in the norm and in pathology].
Regulation metabolism in a cell is realised by enzymes arranged into supramolecular complexes. Lactate dehydrogenase (LDH) and alcohol dehydrogenase (ADH) are involved into formation of various supramolecular complexes. It is supposed that oxidoreductases LDH and ADH can form uniform functional supramolecular complex, exerting essential influence on redox potential of the cell.
Zimin
Iu V
IuV
Research Institute of Traumatology and Orthopedics, Verkhne-Volzhskaya nab. 18, Nizhniy Novgorod 603155, Russia. yuzimin@mail.ru
Siatkin
S P
SP
Berezov
T T
TT
D000426:Alcohol Dehydrogenase / Q000378:metabolism*; D000818:Animals; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D046911:Macromolecular Substances; D009243:NAD / Q000378:metabolism; D010084:Oxidation-Reduction
D046911:Macromolecular Substances; D009243:NAD; D000426:Alcohol Dehydrogenase; D007770:L-Lactate Dehydrogenase