title: Preliminary results of Cytos 2 experiment.
abstract: Cytos 2 experiment, carried out during the French-Soviet manned flight (July 1982), has studied the antibiotics sensitivity of bacteria cultivated in vitro during the orbital flight. The results show an increase of the antibiotics resistance and a larger thickness of the cellular envelope for the inflight cells. The increase of antibiotics resistance can be related to a stimulating effect of space on the cell growth rate or to changes of the cellular envelope structure.
authors.affiliation: Groupe de Recherches, Biologiques Spatiales, Universite Paul Sabatier, Toulouse, France.
authors.forename: R
authors.initials: R
authors.lastname: Tixador
authors.forename: G
authors.initials: G
authors.lastname: Richoilley
authors.forename: G
authors.initials: G
authors.lastname: Gasset
authors.forename: H
authors.initials: H
authors.lastname: Planel
authors.forename: N
authors.initials: N
authors.lastname: Moatti
authors.forename: L
authors.initials: L
authors.lastname: Lapchine
authors.forename: L
authors.initials: L
authors.lastname: Enjalbert
authors.forename: J
authors.initials: J
authors.lastname: Raffin
authors.forename: R
authors.initials: R
authors.lastname: Bost
authors.forename: S N
authors.initials: SN
authors.lastname: Zaloguev
authors.forename: M P
authors.initials: MP
authors.lastname: Bragina
authors.forename: A F
authors.initials: AF
authors.lastname: Moroz
authors.forename: N G
authors.initials: NG
authors.lastname: Antsiferova
authors.forename: F M
authors.initials: FM
authors.lastname: Kirilova
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003091:Colistin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects* / Q000648:ultrastructure; D007612:Kanamycin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010068:Oxacillin / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology; D013026:Space Flight; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000648:ultrastructure; D014893:Weightlessness
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D007612:Kanamycin; D004917:Erythromycin; D002701:Chloramphenicol; D010068:Oxacillin; D003091:Colistin