Heavy-ion induced genetic changes and evolution processes.
On Moon and Mars, there will be more galactic cosmic rays and higher radiation doses than on earth.  Our experimental studies showed that heavy ion radiation can effectively cause mutation and chromosome aberrations and that high-LET heavy-ion induced mutants can be irreversible.  Chromosome translocations and deletions are common in cells irradiated by heavy particles, and ionizing radiations are effective in causing hyperploidy.  The importance of the genetic changes in the evolution of life is an interesting question.  Through evolution, there is an increase of DNA content in cells from lower forms of life to higher organisms.  The DNA content, however, reached a plateau in vertebrates.  By increasing DNA content, there can be an increase of information in the cell.  For a given DNA content, the quality of information can be changed by rearranging the DNA.  Because radiation can cause hyperploidy, an increase of DNA content in cells, and can induce DNA rearrangement, it is likely that the evolution of life on Mars will be effected by its radiation environment.  A simple analysis shows that the radiation level on Mars may cause a mutation frequency comparable to that of the spontaneous mutation rate on Earth.  To the extent that mutation plays a role in adaptation, radiation alone on Mars may thus provide sufficient mutation for the evolution of life.
Yang
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NASA Johnson Space Center, Houston, TX 77058, USA.
Craise
L M
LM
Durante
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M
Mei
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M
D000818:Animals; D005075:Biological Evolution; D002460:Cell Line; D002869:Chromosome Aberrations; D003359:Cosmic Radiation / Q000009:adverse effects*; D004307:Dose-Response Relationship, Radiation; D004622:Embryo, Mammalian / Q000166:cytology / Q000528:radiation effects; D018499:Linear Energy Transfer; D018535:Mars; D051379:Mice; D016081:Moon; D016296:Mutagenesis / Q000528:radiation effects; D009154:Mutation; D011831:Radiation Genetics; D011839:Radiation, Ionizing; D051381:Rats; D012062:Relative Biological Effectiveness