The "patch-clamp" technique and its application in investigations of the properties of human T lymphocyte potassium channels.
The first part of this review presents a historical outline on the development of experimental methods in electrophysiology starting from the first experiments performed in the 1920s and ending with the "patch-clamp" technique. Recording configurations of the "patch-clamp" technique are briefly reviewed in the second section. The areas of application of the configurations are shown. The last section contains a short review on the available data of "patch-clamp" studies on the expression and properties of potassium channels in human T lymphocytes (TL). Problems that require further investigation are briefly presented.
Teisseyre
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Department of Biophysics, Wrocław Medical University, Poland.
D004594:Electrophysiology / Q000379:methods*; D006801:Humans; D018408:Patch-Clamp Techniques / Q000379:methods*; D015221:Potassium Channels / Q000737:chemistry*; D013601:T-Lymphocytes / Q000737:chemistry* / Q000502:physiology
D015221:Potassium Channels