title: Subtotal laryngectomy with cricohyoidopexy as first treatment procedure for supraglottic carcinoma: Institut Gustave-Roussy experience (146 cases, 1974-1997).
abstract: METHODS
  Between 1974 and 1997, 297 patients underwent a subtotal laryngectomy at the Institut Gustave-Roussy; 146 of these patients underwent cricohyoidopexy (CHP) for a supraglottic primary as their first treatment. The majority of patients were men (137) aged from 33 to 78 years (median 54 years). The tumour stage at presentation was T1 in 2, T2 in 87, T3 in 53 (preepiglottic space involvement), and T4 (minimal thyroid cartilage invasion) in 4 patients. One hundred and twenty-five patients were N0 (86%) and 21 patients were Np (palpable); 98% had homolateral and 55% had bilateral neck dissections.
  
  
  RESULTS
  One patient died postoperatively of a myocardial infarction and 68% patients had an uneventful course. Aspiration was the commonest complication (23 patients, 19%). The median time to removal of the tracheotomy cannula was 10 days and for the nasogastric tube 21 days during the past 10 years. Completion of subtotal laryngectomy into total laryngectomy was done in 21 cases (15%): eight times because of oncological events [five local failures, two second primary (hypopharynx), one positive margin] and 13 times because of aspiration (9%). There were six local failures (4%) and eight nodal failures (5%). The rates of distant metastases and second primaries were 6% and 16% respectively. Half of the local and nodal failures were subsequently sterilized. Findings at death were two local recurrences, four nodal recurrences, eight distant metastases, and 11 second primaries. The 3- and 5-year overall survival rates were 92% and 88% respectively, with an overall laryngeal preservation rate of 86%.
  
  
  CONCLUSIONS
  When supraglottic laryngectomy is not feasible for supraglottic cancer, subtotal laryngectomy with CHP is a safe and effective oncological procedure, with preservation of satisfactory laryngeal function.
authors.affiliation: Département de Chirurgie Cervico-Faciale, Institut Gustave-Roussy, Villejuif, France.
authors.forename: G
authors.initials: G
authors.lastname: Schwaab
authors.forename: F
authors.initials: F
authors.lastname: Kolb
authors.forename: M
authors.initials: M
authors.lastname: Julieron
authors.forename: F
authors.initials: F
authors.lastname: Janot
authors.forename: A M
authors.initials: AM
authors.lastname: Le Ridant
authors.forename: G
authors.initials: G
authors.lastname: Mamelle
authors.forename: P
authors.initials: P
authors.lastname: Marandas
authors.forename: V N
authors.initials: VN
authors.lastname: Koka
authors.forename: B
authors.initials: B
authors.lastname: Luboinski
mesh_terms: D000328:Adult; D000368:Aged; D003413:Cricoid Cartilage / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005602:France; D005931:Glottis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D006928:Hyoid Bone / Q000473:pathology / Q000601:surgery*; D007822:Laryngeal Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D015996:Survival Rate; D013997:Time Factors; D017211:Treatment Failure