title: Tandem chain extension-homoenolate formation: the formation of alpha-methylated-gamma-keto esters.
abstract: A tandem chain extension-homoenolate formation reaction is described. The treatment of beta-keto esters with the Furukawa reagent followed by exposure to a catalytic amount of trimethylsilyl chloride provides access to an ester homoenolate. Reaction: see text.
authors.affiliation: Department of Chemistry, University of New Hampshire, Durham, NH 03824, USA.
authors.forename: R
authors.initials: R
authors.lastname: Hilgenkamp
authors.forename: C K
authors.initials: CK
authors.lastname: Zercher
mesh_terms: D004952:Esters / Q000138:chemical synthesis*; D007536:Isomerism; D007651:Keto Acids / Q000138:chemical synthesis*
chemical_list: D004952:Esters; D007651:Keto Acids