Successful hyperbaric oxygen treatment of life-threatening hemorrhagic cystitis after allogeneic bone marrow transplantation.
Hemorrhagic cystitis (HC) is a major cause of morbidity after allogeneic bone marrow transplantation (BMT). Many therapies have been investigated to prevent or treat HC, but effective treatment for HC is still limited. While the efficacy of hyperbaric oxygen therapy has been established for HC due to chemotherapy and/or radiation therapy, its role in HC occurring after allogeneic BMT has yet to be defined. We report two cases of life-threatening late-onset HC after allogeneic BMT in children, which resolved after treatment with hyperbaric oxygen.
Hattori
K
K
Department of Pediatrics, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Yabe
M
M
Matsumoto
M
M
Kudo
Y
Y
Yasuda
Y
Y
Inoue
H
H
Minami
S
S
Miyakita
H
H
Kawamura
N
N
Komori
K
K
Yamamoto
I
I
Yabe
H
H
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D016638:Critical Illness; D003556:Cystitis / Q000209:etiology / Q000628:therapy*; D018572:Disease-Free Survival; D006474:Hemorrhagic Disorders / Q000209:etiology / Q000628:therapy; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D014184:Transplantation, Homologous / Q000009:adverse effects