Mixed echo train acquisition displacement encoding with stimulated echoes: an optimized DENSE method for in vivo functional imaging of the human heart.
Mixed echo train acquisition displacement encoding with stimulated echoes (meta-DENSE) is a phase-based displacement mapping technique suitable for imaging myocardial function. This method has been optimized for use with patients who have a history of myocardial infarction. The total scan time is 12-14 heartbeats for an in-plane resolution of 2.8 x 2.8 mm2. Myocardial strain is mapped at this resolution with an accuracy of 2% strain in vivo. Compared to standard stimulated echo (STE) methods, both data acquisition speed and resolution are improved with inversion-recovery FID suppression and the meta-DENSE readout scheme. Data processing requires minimal user intervention and provides a rapid quantitative feedback on the MRI scanner for evaluating cardiac function. Published 2001 Wiley-Liss, Inc.
Aletras
A H
AH
Laboratory of Cardiac Energetics, NHLBI, NIH, Bethesda, Maryland 20892-1061, USA. Anthony_Aletras@nih.gov
Wen
H
H
D016477:Artifacts; D017352:Echo-Planar Imaging / Q000295:instrumentation*; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D009200:Myocardial Contraction / Q000502:physiology*; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology; D019047:Phantoms, Imaging; D012016:Reference Values; D013599:Systole / Q000502:physiology