title: Moving-table reduced-dose gadolinium-enhanced three-dimensional magnetic resonance angiography: velocity-dependent method with three-phase gadolinium infusion.
abstract: The purpose of this study was to develop a method for reducing gadolinium dose and suppressing venous overlap in moving-table three-dimensional (3D) magnetic resonance (MR) angiography from the abdomen to the feet. Thirty-one patients underwent three-phase infusion of 16-18 mL of gadolinium: infusion rates and imaging times were determined after taking into account mean blood flow velocity, so that image acquisition was synchronized with peak arterial enhancement at both the first and third stations (velocity-dependent method). Twenty-three other patients underwent slow infusion of 38 mL of gadolinium with fixed acquisition time (high-dose method). The image quality for the two methods was compared. The velocity-dependent method produced good image quality with significantly less venous overlap than the high-dose method, especially in the below-the-knee region (P <.001). The velocity-dependent method provides satisfactory MR angiograms using 16-18 mL of gadolinium in patients having various blood flow velocities.
authors.affiliation: Department of Radiology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi City, Osaka 594-0076, Japan. mkita@muh.biglobe.ne.jp
authors.forename: M
authors.initials: M
authors.lastname: Kita
authors.forename: Y
authors.initials: Y
authors.lastname: Mitani
authors.forename: H
authors.initials: H
authors.lastname: Tanihata
authors.forename: K
authors.initials: K
authors.lastname: Kita
authors.forename: M
authors.initials: M
authors.lastname: Sato
authors.forename: O
authors.initials: O
authors.lastname: Takizawa
authors.forename: G
authors.initials: G
authors.lastname: Laub
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001158:Arteries / Q000473:pathology*; D001783:Blood Flow Velocity; D003251:Constriction, Pathologic / Q000175:diagnosis; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D005682:Gadolinium / Q000008:administration & dosage*; D006801:Humans; D007089:Image Enhancement; D021621:Imaging, Three-Dimensional; D007866:Leg / Q000098:blood supply; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008954:Models, Biological
chemical_list: D003287:Contrast Media; D005682:Gadolinium