title: A case of glucagonoma with high uptake on F-18 fluorodeoxyglucose positron emission tomography.
abstract: Glucagonomas are relatively rare, and can be difficult to differentiate from other pancreatic tumors. A 62-year-old woman who had suffered from diabetes mellitus was hospitalized for further evaluation of a space-occupying lesion in the head of the pancreas and tumors in the liver. F-18 fluorodeoxyglucose positron emission tomography revealed accumulation of isotope corresponding to a tumor of the pancreas with a standardized uptake value of 4.3, and tumors in the liver with standardized uptake values of 2.4 and 2.8. The serum glucagon level was high (1,170 pg/ml) and the secretin tolerance test was negative. She was diagnosed with glucagonoma with a high serum glucagon level and clinical findings. It is suggested that glucagonoma may be one of the tumors which show high uptake of F-18 fluorodeoxyglucose.
authors.affiliation: Third Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nishiguchi
authors.forename: S
authors.initials: S
authors.lastname: Shiomi
authors.forename: H
authors.initials: H
authors.lastname: Ishizu
authors.forename: Y
authors.initials: Y
authors.lastname: Iwata
authors.forename: H
authors.initials: H
authors.lastname: Kurooka
authors.forename: S
authors.initials: S
authors.lastname: Minamitani
authors.forename: D
authors.initials: D
authors.lastname: Habu
authors.forename: J
authors.initials: J
authors.lastname: Kawabe
authors.forename: H
authors.initials: H
authors.lastname: Ochi
mesh_terms: D001692:Biological Transport; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics*; D005935:Glucagonoma / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D014018:Tissue Distribution; D014055:Tomography, Emission-Computed; D014463:Ultrasonography
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18