title: Contribution of vascular endothelial growth factor to the Nottingham prognostic index in node-negative breast cancer.
abstract: The prognostic contribution of intratumour VEGF, the most important factor in tumour-induced angiogenesis, to NPI was evaluated by using flexible modelling in a series of 226 N-primary breast cancer patients in which steroid receptors and cell proliferation were also accounted for. VEGF provided an additional prognostic contribution to NPI mainly within ER-poor tumours.
authors.affiliation: Unità Operativa Determinanti Biomolecolari nella Prognosi e Terapia, Università degli Studi di Milano, Milan, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Coradini
authors.forename: P
authors.initials: P
authors.lastname: Boracchi
authors.forename: M G
authors.initials: MG
authors.lastname: Daidone
authors.forename: C
authors.initials: C
authors.lastname: Pellizzaro
authors.forename: P
authors.initials: P
authors.lastname: Miodini
authors.forename: M
authors.initials: M
authors.lastname: Ammatuna
authors.forename: G
authors.initials: G
authors.lastname: Tomasic
authors.forename: E
authors.initials: E
authors.lastname: Biganzoli
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000401:mortality; D002455:Cell Division; D018572:Disease-Free Survival; D016228:Endothelial Growth Factors / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D008198:Lymph Nodes; D008222:Lymphokines / Q000378:metabolism*; D011379:Prognosis; D011960:Receptors, Estrogen / Q000378:metabolism; D011980:Receptors, Progesterone / Q000378:metabolism; D015996:Survival Rate; D006113:United Kingdom; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
chemical_list: D016228:Endothelial Growth Factors; D008222:Lymphokines; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors