Synthesis of isoquinolines and naphthyridines by electrophilic ring closure of iminoalkynes.
Substituted isoquinolines and naphthyridines have been prepared in good to excellent yields by the reaction of iminoalkynes with a variety of electrophiles under mild reaction conditions. Reaction: see text.
Huang
Q
Q
Department of Chemistry, Iowa State University, Ames, IA 50011, USA.
Hunter
J A
JA
Larock
R C
RC
D001685:Biological Factors / Q000138:chemical synthesis; D007097:Imines / Q000737:chemistry; D007546:Isoquinolines / Q000138:chemical synthesis*; D009287:Naphthyridines / Q000138:chemical synthesis*
D001685:Biological Factors; D007097:Imines; D007546:Isoquinolines; D009287:Naphthyridines