Cortisol, insulin and leptin during space flight and bed rest.
Most ground based models for studying muscle atrophy and bone loss show reasonable fidelity to the space flight situation. However there are some differences. Investigation of the reasons for these differences can provide useful information about humans during space flight and aid in the refinement of ground based models. This report discusses three such differences, the relationships between: (i) cortisol and the protein loss, (ii) cortisol and ACTH and (iii) leptin, insulin and food intake.
Stein
T P
TP
Department of Surgery, University of Medicine and Dentistry of New Jersey-SOM, Stratford 08084, USA.
Schluter
M D
MD
Leskiw
M J
MJ
D000324:Adrenocorticotropic Hormone / Q000378:metabolism / Q000652:urine; D001510:Bed Rest; D004435:Eating; D005260:Female; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism* / Q000652:urine; D007328:Insulin / Q000378:metabolism*; D020738:Leptin / Q000378:metabolism* / Q000652:urine; D008297:Male; D013026:Space Flight; D014893:Weightlessness
D007328:Insulin; D020738:Leptin; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone