The 2nd International Symposium on Circulating Nucleic Acids in Plasma and Serum (CNAPS-2), Hong Kong, February 20-21, 2001.
The detection of free, i.e. not cell-bound, circulating nucleic acids was described only recently. The second international symposium dealing with this research subject presented the progress made in this field. The topics included in the meeting report are: microsatellite alterations in circulating fetal DNA and DNA isolated from tumor patients; detection and quantification of viral DNA associated with malignant diseases; detection and quantification of mRNA associated with benign and malignant diseases; and application of these methods in areas like tumor detection, detection of women pregnant with a fetus carrying a genetic disorder, transplantation medicine, the care for trauma patients and the detection of circulating foreign DNA (like Plasmodium in people at risk for malaria).
Fleischhacker
M
M
Universitätsklinikum Charité, Medizinische Klinik II m.S. Onkologie und Hämatologie, Schumannstr. 20-21, D-10117 Berlin, Germany. michael.fleischhacker@charite.de
D000818:Animals; D016470:Bacteremia / Q000175:diagnosis; D004269:DNA, Bacterial / Q000097:blood; D004273:DNA, Neoplasm / Q000097:blood; D016054:DNA, Protozoan / Q000097:blood; D004279:DNA, Viral / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005315:Fetal Diseases / Q000097:blood / Q000235:genetics; D030342:Genetic Diseases, Inborn / Q000097:blood / Q000175:diagnosis / Q000196:embryology / Q000235:genetics; D006801:Humans; D016778:Malaria, Falciparum / Q000097:blood / Q000175:diagnosis; D008431:Maternal-Fetal Exchange; D018895:Microsatellite Repeats; D009369:Neoplasms / Q000097:blood / Q000175:diagnosis; D009696:Nucleic Acids / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods; D014766:Viremia / Q000175:diagnosis; D014947:Wounds and Injuries / Q000097:blood
D004269:DNA, Bacterial; D004273:DNA, Neoplasm; D016054:DNA, Protozoan; D004279:DNA, Viral; D009696:Nucleic Acids