title: [Humoral immune response in patients with bronchopulmanory infections to immunotherapy].
abstract: The content of IgA, IgM, IgG and the level of specific antibodies in the blood serum of patients with bronchopulmonary diseases after a course of immunotherapy with polycomponent vaccine B[symbol: see text]-4 was studied. A rise in the concentration of IgM due to the synthesis of specific antibodies to Proteus vulgaris, Escherichia coli and Klebsiella pneumoniae was found to occur. The examination of sick children revealed that a high proportion of them (54%) showed a pronounced decrease in the level of IgA. The use of the preparation made it possible to enhance the level of IgA.
authors.affiliation: Mechikov Research Institute for Vaccines and Sera, Moscow, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Slatinova
authors.forename: M A
authors.initials: MA
authors.lastname: Mokronosova
authors.forename: S A
authors.initials: SA
authors.lastname: Skhodova
authors.forename: L I
authors.initials: LI
authors.lastname: Krasnoproshina
mesh_terms: D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D001249:Asthma / Q000276:immunology* / Q000628:therapy; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D001991:Bronchitis / Q000276:immunology* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D017778:Vaccines, Combined / Q000627:therapeutic use*
chemical_list: D001428:Bacterial Vaccines; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; C088865:VP-4 vaccine; D017778:Vaccines, Combined