title: Simultaneous bilateral upper extremity venous thrombosis in a factor V Leiden heterozygote: a case report and review.
abstract: Primary upper extremity deep venous thrombosis (DVT), or effort thrombosis, typically occurs in young, healthy individuals with a history of repetitive upper extremity movement while secondary upper extremity DVT is associated with a number of predisposing factors. The role of factors such as hypercoagulability in the development of effort thrombosis is less well described. This report describes a previously healthy 21-year-old man who presented with simultaneous bilateral upper extremity DVT after hours of pushing and lifting a heavy wheelbarrow. Treatment included thrombolytic therapy followed by delayed venolysis and vein patch angioplasty. Hypercoagulable screening revealed factor V Leiden heterozygous characteristics.
authors.affiliation: Department of Surgery, St. Joseph Mercy Hospital, Michigan Heart and Vascular Institute, 5325 Elliott Drive, Ann Arbor, MI 48106, USA.
authors.forename: V V
authors.initials: VV
authors.lastname: Sullivan
authors.forename: S W
authors.initials: SW
authors.lastname: Wolk
authors.forename: W M
authors.initials: WM
authors.lastname: Whitehouse
mesh_terms: D000328:Adult; D001132:Arm / Q000000981:diagnostic imaging / Q000473:pathology*; D001367:Axillary Vein / Q000000981:diagnostic imaging / Q000601:surgery; D005165:Factor V / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D008297:Male; D013350:Subclavian Vein / Q000000981:diagnostic imaging / Q000601:surgery; D018616:Ultrasonography, Doppler, Duplex; D020246:Venous Thrombosis / Q000235:genetics* / Q000628:therapy*
chemical_list: C095381:factor V Leiden; D005165:Factor V