[Netilmicin in the complex therapy of pneumonia in newborns].
Clinical efficacy of netilmicin was evaluated at 22 newborns (body weight from 1000 to 3600 g, delivery on pregnancy period from 28 to 41 weeks) with pneumonia caused by artificial pulmonary ventilation. Pneumonia was moderate at 13 patients and severe at 9 patients. Microorganisms isolated from tracheobronchial aspirates were mainly (in 19 cases of 22) susceptible to netilmicin. The usage of netilmicin in combination with cephalosporins was effective at the main part of the newborns and resulted with the full recovery of 11 newborns (all the patients with moderate pneumonia), in 9 cases improvement was registered (including 7 newborns with severe pneumonia). Newborns with severe pneumonia had a slow pathogens elimination.
Dement'eva
G M
GM
Moscow Research Institute of Pediatrics and Pediatric Surgery, Municipal Clinical Hospital No 13.
Kushnareva
M V
MV
Frolova
M I
MI
Chernonog
I N
IN
Kuznetsova
L K
LK
Samoĭlova
L N
LN
D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D009428:Netilmicin / Q000627:therapeutic use*; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000382:microbiology
D005839:Gentamicins; D009428:Netilmicin