The effects of hypokinesia in primates on bone strength.
A 14 days ground based primate hypokinesia investigation was conducted to determine what changes, if any, in bone strength may be demonstrated following 2 weeks cast immobilization and at 14 davs after removal from casts. Controlled compressive loads were applied to vertebral bodies excised from control, 2 weeks immobilization and 2 weeks post immobilization Rhesus monkeys. The material properties reported herein are ultimate load, displacement to ultimate load, stiffness and energy to ultimate load.  These results show a decrease in bone strength following immobilization and a still further decrease in bone strength after 14 days.
Kazarian
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Air Force Systems Command, Biodynamic Effects Branch, Wright-Patterson Air Force Base, Ohio, USA.
Von Gierke
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HE
D000818:Animals; D001835:Body Weight; D018488:Bone Demineralization, Pathologic / Q000503:physiopathology; D015519:Bone Density; D001842:Bone and Bones / Q000502:physiology*; D019245:Compressive Strength; D007103:Immobilization; D008159:Lumbar Vertebrae / Q000502:physiology*; D008253:Macaca mulatta; D008297:Male