title: The chondrogenic potential of carbon fiber and carbon fiber periosteum implants: an ultrastructural study in the rabbit.
abstract: The articular tissue generated on carbon fiber rods in rabbit knee joints after 75 days of intermittent active motion was compared with tissue generated on carbon fiber rods whose articular surfaces were covered with a free reversed periosteal graft. Both methods were effective in generating articular tissue; however, tissue with ultrastructural characteristics similar to those of hyaline cartilage was noted more frequently on the composite implants. If such composite implants were clinically effective then they might be useful in treating symptomatic osteochondral defects.
authors.affiliation: Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
authors.forename: W
authors.initials: W
authors.lastname: Curtin
authors.forename: W
authors.initials: W
authors.lastname: Reville
authors.forename: M
authors.initials: M
authors.lastname: Heapes
authors.forename: J
authors.initials: J
authors.lastname: Lyons
authors.forename: D
authors.initials: D
authors.lastname: Muckle
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002244:Carbon; D000077482:Carbon Fiber; D002358:Cartilage, Articular / Q000502:physiology / Q000648:ultrastructure*; D019902:Chondrocytes / Q000502:physiology / Q000648:ultrastructure; D020219:Chondrogenesis / Q000502:physiology*; D005121:Extremities; D007596:Joints; D008854:Microscopy, Electron; D010521:Periosteum / Q000502:physiology / Q000637:transplantation; D019736:Prostheses and Implants; D011817:Rabbits
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000077482:Carbon Fiber; D002244:Carbon