Bakuchiol from Psoralea corylifolia inhibits the expression of inducible nitric oxide synthase gene via the inactivation of nuclear transcription factor-kappaB in RAW 264.7 macrophages.
Pae
H O
HO
Medicinal Resources Research Center of Wonkwang University, Iksan, Chonbug, South Korea.
Cho
H
H
Oh
G S
GS
Kim
N Y
NY
Song
E K
EK
Kim
Y C
YC
Yun
Y G
YG
Kang
C L
CL
Kim
J D
JD
Kim
J M
JM
Chung
H T
HT
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D015152:Blotting, Northern; D015153:Blotting, Western; D002460:Cell Line; D002467:Cell Nucleus / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D004586:Electrophoresis; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects*; D007202:Indicators and Reagents; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D016328:NF-kappa B / Q000187:drug effects; D009569:Nitric Oxide / Q000096:biosynthesis; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors* / Q000096:biosynthesis* / Q000235:genetics; D052247:Nitric Oxide Synthase Type II; D010636:Phenols / Q000494:pharmacology*; D028321:Plant Preparations / Q000494:pharmacology; D029907:Psoralea / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004791:Enzyme Inhibitors; D007202:Indicators and Reagents; D016328:NF-kappa B; D010636:Phenols; D028321:Plant Preparations; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; C496317:Nos2 protein, mouse; C012765:bakuchiol