title: Clinical verification of a unilateral otolith test.
abstract: In a previous study we reported promising results for a new test to differentiate in vivo unilateral otolith functions. That study pointed to a need for further validation on known  pathological cases.  In this presentation we will detail the results gathered on a group of clinically verified vestibular defectives (verum) and a normal (control) group. The subjects in the verum group were former patients of the ENT clinic of the university hospital.  These subjects had usually suffered from neurinoma of the VIIth cranial nerve or inner ear infections.  All had reguired surgical intervention including removal of the vestibular system.  The patients were contacted usually two or more years postoperatively.  A group of students from the pre- and clinical phase of medical training served as control.  Both groups were subjected to standardized clinical tests.  These tests served to reconfirm the intra- or postoperative diagnosis of unilateral vestibular loss in the verum group.  In the control group they had to establish the normalcy of the responses of the vestibular system.  Both groups then underwent testing on our eccentric rotary chain in the manner described before.  Preliminary results of the trials indicate that this test may indeed for the first time offer a chance to look at isolated otolith apparati in vivo.
authors.affiliation: Johannes-Gutenberg University, Dept. Physiology.
authors.forename: J
authors.initials: J
authors.lastname: Wetzig
authors.forename: K
authors.initials: K
authors.lastname: Hofstetter-Degen
authors.forename: J
authors.initials: J
authors.lastname: Maurer
authors.forename: R J
authors.initials: RJ
authors.lastname: von Baumgarten
mesh_terms: D000328:Adult; D000368:Aged; D004198:Disease Susceptibility; D007758:Ear, Inner / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010037:Otolithic Membrane / Q000502:physiology*; D011434:Proprioception / Q000502:physiology*; D012399:Rotation / Q000009:adverse effects*; D018489:Space Motion Sickness / Q000209:etiology / Q000503:physiopathology; D013647:Task Performance and Analysis; D014724:Vestibular Function Tests