Sculpturing new muscle phenotypes.
Changes in the pattern of muscle activity are followed by new patterns of protein synthesis, both in the contractile elements and in the enzymes of energy metabolism.  Although the signal transducers have not been identified, techniques of molecular biology have clearly shown that the adaptive responses are the regulated consequence of differential gene expression.
Babij
P
P
Department of Physiology and Cell Biology, University of Texas Medical School at Houston 77225, USA.
Booth
F W
FW
D000222:Adaptation, Physiological / Q000235:genetics; D000818:Animals; D004274:DNA, Recombinant; D015444:Exercise / Q000502:physiology; D015870:Gene Expression / Q000502:physiology*; D006801:Humans; D024510:Muscle Development; D009124:Muscle Proteins / Q000235:genetics* / Q000502:physiology*; D018482:Muscle, Skeletal / Q000254:growth & development / Q000378:metabolism*; D010641:Phenotype; D014176:Protein Biosynthesis / Q000502:physiology; D012333:RNA, Messenger; D014157:Transcription Factors
D004274:DNA, Recombinant; D009124:Muscle Proteins; D012333:RNA, Messenger; D014157:Transcription Factors