Methadone may promote HIV replication: study.
Investigators at the University of Pennsylvania School of Medicine have found that HIV replication in vitro is promoted by the opiate methadone. Although this research is a long way from concluding that injection-drug-using HIV patients should avoid methadone treatment, it does raise questions that will need to be answered through further studies.
Douglas
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SD
Section of Immunology, Children's Hospital of Philadelphia, USA.
D006678:HIV / Q000235:genetics / Q000502:physiology*; D016325:HIV Long Terminal Repeat; D006801:Humans; D008691:Methadone / Q000494:pharmacology* / Q000627:therapeutic use; D019713:Receptors, CCR5 / Q000235:genetics; D014779:Virus Replication / Q000187:drug effects*
D019713:Receptors, CCR5; D008691:Methadone