title: Thymic carcinoids in multiple endocrine neoplasia-type 1.
abstract: We report a case of a 45-year-old man with thymic carcinoids in multiple endocrine neoplasm-type 1. Extended total thymectomy was performed through a median sternotomy, and the mediastinal regional lymph nodes and fibroadipose tissue were dissected. Multiple endocrine neoplasm-type 1 related thymic carcinoids are rare and have a poor prognosis. The efficacy of radiotherapy and chemotherapy for prolonging survival is limited, and an aggressive surgical approach with complete excision of the tumor with resection of the peripheral tissues and dissection of the mediastinal lymph nodes seems to be the best available treatment today. We have found that this practice of thymectomy at an early stage in combination with genetic and effective radiological treatment can be effective for multiple endocrine neoplasm-type 1 patients.
authors.affiliation: Department of Thoracic Surgery, Hiroshima Prefectural Hospital, 1-5-54 Ujinakanda, Minami-ku, Hiroshima 734-8530, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hirai
authors.forename: Y
authors.initials: Y
authors.lastname: Hamanaka
authors.forename: N
authors.initials: N
authors.lastname: Mitsui
authors.forename: H
authors.initials: H
authors.lastname: Kumagai
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
mesh_terms: D002276:Carcinoid Tumor / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018761:Multiple Endocrine Neoplasia Type 1 / Q000473:pathology*; D013953:Thymus Neoplasms / Q000473:pathology*