Bridged cyclic oligoribonucleotides--towards models for codon-anticodon pairing.
Only three base pairs make up for stable double helices of regular A-type if both helix ends are bridged by flexible non-nucleotide linkers. These cyclic oligoribonucleotides are used as model systems for codon-anticodon pairing in order to reveal base stacking effects arising from structurally relevant bases in the direct neighbourhood of the core triplet duplex.
Micura
R
R
Institute of Chemistry, University of Linz, Altenbergerstr. 69, A-4040 Linz, Austria.
Pils
W
W
Grubmayr
K
K
Ebert
M O
MO
Jaun
B
B
D000926:Anticodon / Q000737:chemistry*; D003062:Codon / Q000737:chemistry*; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D009690:Nucleic Acid Conformation; D009843:Oligoribonucleotides / Q000737:chemistry* / Q000235:genetics
D000926:Anticodon; D003062:Codon; D009843:Oligoribonucleotides