title: Resolution of racemic mixtures of carbocyclic analogues of nucleosides and assignment of their absolute configuration.
abstract: Racemic trans-6-chloro-9-[2-(hydroxymethyl)cyclopentyl]purine was resolved using HPLC with a chiral column. The absolute configurations of the enantiomers were determined by NMR studies of their (R)- and (S)-methoxyphenylacetates.
authors.affiliation: Departamento de Química Orgánica, Universidad de Vigo, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Besada
authors.forename: C
authors.initials: C
authors.lastname: Terán
authors.forename: E
authors.initials: E
authors.lastname: Quezada
authors.forename: J M
authors.initials: JM
authors.lastname: Seco
authors.forename: E
authors.initials: E
authors.lastname: Uriarte
mesh_terms: D002851:Chromatography, High Pressure Liquid; D019906:Nuclear Magnetic Resonance, Biomolecular; D009690:Nucleic Acid Conformation; D009705:Nucleosides / Q000737:chemistry / Q000302:isolation & purification*; D011687:Purines / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: C442885:6-chloro-9-(2(hydroxymethyl)cyclopentyl)purine; D009705:Nucleosides; D011687:Purines