title: Agenesis of gallbladder in symptomatic patients.
abstract: Three women and one man among 771 patients, who underwent laparotomy with diagnosis of symptomatic gallbladder disease over a period of 5 years, were found to have agenesis of the gallbladder. Preoperative ultrasonography suggested cholelithiasis in all the four patients; three patients with jaundice had choledocholithiasis in addition. The absence of gallbladder was established by meticulous operative exploration and carefully repeated ultrasonography in postoperative period. The patients having choledocholithiasis underwent choledocholithotomy, while the fourth patient had no definitive procedure. One patient expired on 17th postoperative day following biliary leak, septicemia and liver failure. Another two patients were well and symptom free, while the fourth patient remained symptomatic. Awareness of the possibility of agenesis of gallbladder may allow the surgeon to attempt confirmation of diagnosis by non-operative methods and avoid surgical exploration in specific instances.
authors.affiliation: Department of Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal. bhupendrakjain@hotmail.com
authors.forename: B K
authors.initials: BK
authors.lastname: Jain
authors.forename: D N
authors.initials: DN
authors.lastname: Das
authors.forename: R K
authors.initials: RK
authors.lastname: Singh
authors.forename: R
authors.initials: R
authors.lastname: Kukreti
authors.forename: P
authors.initials: P
authors.lastname: Dargan
mesh_terms: D015746:Abdominal Pain / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D000328:Adult; D002769:Cholelithiasis / Q000000981:diagnostic imaging; D002779:Cholestasis / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005704:Gallbladder / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D006801:Humans; D007813:Laparotomy / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D015996:Survival Rate; D014463:Ultrasonography