Bone ultrastructural changes in Bion 11 rhesus monkeys.
Iliac crest biopsies of Bion 11 monkeys were examined by electron microscopy. The flight samples contained a large number of inactive osteoblasts. Together with ultrastructural changes of the rough endoplasmic reticulum and the Golgi complex, the predominance of inactive osteoblasts pointed to a lower rate of specific syntheses.  Some osteoblasts were transformed to fibroblast-like cells. It was found that osteogenesis declined, osteoid mineralization changed, and fibrotic zones developed.
Rodionova
N V
NV
Schmalhauzen Institute of Zoology, Ukrainian Academy of Sciences, Kiev, Ukraine.
Shevel
I M
IM
Oganov
V S
VS
Novikov
V E
VE
Kabitskaya
O E
OE
D000222:Adaptation, Physiological; D000818:Animals; D001842:Bone and Bones / Q000166:cytology / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D007085:Ilium / Q000166:cytology / Q000648:ultrastructure*; D008253:Macaca mulatta; D008297:Male; D008854:Microscopy, Electron; D010006:Osteoblasts / Q000166:cytology / Q000648:ultrastructure*; D010011:Osteocytes / Q000166:cytology / Q000648:ultrastructure*; D010012:Osteogenesis / Q000502:physiology; D013026:Space Flight; D014893:Weightlessness