title: [Sentinel lymph node excision. Treatment method of the N0 neck in patients with oral and oropharyngeal carcinoma].
abstract: BACKGROUND
  The clinically non-metastatic neck is an unsolved problem in the treatment of oral and oropharyngeal squamous cell carcinomas. A rational procedure is looked for which is neither exaggerated nor neglects the needed safety.
  
  
  METHODS
  15 patients with primary squamous cell carcinomas of the oral cavity and the oropharynx, staging T1-4N0M0 were examined. After peritumoral intramucodermal injection of tc99m-labeled colloidal albumin the lymphoscintigraphy using gamma-camera imaging prior and hand-held gamma-probe during operation were used for identification of the nodes. Selective sentinel lymph node exstirpation was followed by radical tumor resection.
  
  
  RESULTS
  In all cases (n = 41) lymph nodes could be detected, 40 of them were sentinel lymph nodes, distributed to all neck levels, in 5 cases bilateral drainage. 92.5% of sentinel lymph nodes could be actually removed. All but 1 (97.5%) were true-negative. In the positive case modified radical neck dissection harvested another affected node.
  
  
  CONCLUSIONS
  Methodically seen, the sentinel procedure works well and might lead to reduced post-surgical morbidity in about 50% of patients with oral cancer. To date, the procedure should be confined to studies with special requirements to diagnostics and subsequent treatment.
authors.affiliation: Klinik und Poliklinik für Kiefer- und Plastische Gesichtschirurgie, Johann Wolfgang Goethe-Universität Frankfurt am Main. A.Kovacs@em.uni-frankfurt.de
authors.forename: A F
authors.initials: AF
authors.lastname: Kovács
authors.forename: P
authors.initials: P
authors.lastname: Acker
authors.forename: U
authors.initials: U
authors.lastname: Berner
authors.forename: J H
authors.initials: JH
authors.lastname: Risse
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D010039:Otorhinolaryngologic Neoplasms / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D021701:Sentinel Lymph Node Biopsy