Accumulation of 67Ga citrate in early pregnancy.
A 26-year-old pregnant woman complained of chest pain and dyspnea and was diagnosed with malignant lymphoma of the mediastinum. To determine the stage of malignant lymphoma, tumor scintigraphy with 67Ga citrate was performed. 67Ga scintigraphy revealed an abnormal accumulation in the center of the pelvic cavity. An artificial abortion was performed, and the early pregnancy obtained from the abortion showed a prominent uptake of 67Ga citrate ex vivo. 67Ga citrate re-examination, which was performed immediately after the abortion, showed no abnormal accumulation in the pelvic cavity. To our knowledge, this is the first medical report on an aborted tissue investigated ex vivo to determine whether it demonstrated increased uptake of 67Ga citrate.
Kurosaki
H
H
Department of Radiology and Radiation Oncology, Gunma University School of Medicine, Maebashi, Japan. kuro@coo.net
Saito
Y
Y
Kawashima
M
M
Ebara
T
T
Yamakawa
M
M
Mitsuhashi
N
N
D000028:Abortion, Induced; D000328:Adult; D001692:Biological Transport; D002951:Citrates / Q000493:pharmacokinetics*; D005260:Female; D005708:Gallium / Q000493:pharmacokinetics*; D005710:Gallium Radioisotopes / Q000493:pharmacokinetics; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging*; D008657:Metabolic Clearance Rate; D010920:Placenta / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics
D002951:Citrates; D005710:Gallium Radioisotopes; D019275:Radiopharmaceuticals; D005708:Gallium; C103850:gallium citrate