[Effect of concentration of spermatozoids on fertilization of oocytes and human embryo development in vitro].
The correlation between sperm insemination concentrations, rates of normal and abnormal fertilization and embryo development was investigated. For male factor patients fertilization rates are significantly lower than for female factor. We have found the increased fertilization rate for male factor, if insemination concentration increased from 10 x 10(4) to 15 x 10(4) per 1 ml. In cases of severe male factor infertility the concentration of sperm of 30 x 10(4) per 1 ml had no effect. We have found no difference in abnormal rates of fertilization, when the number of sperm increased in male factor. The correlation between the frequency of polysperm zygote and slightly increased insemination concentration was observed in patients with normal sperm.
Vorob'eva
O A
OA
D. O. Ott Institute of Obstetrics and Gynecology RAMN, St. Petersburg.
Leont'eva
O A
OA
D047108:Embryonic Development; D005314:Embryonic and Fetal Development; D005260:Female; D005298:Fertility; D006801:Humans; D008297:Male; D009865:Oocytes / Q000166:cytology*; D011247:Pregnancy; D013076:Sperm Count; D013084:Sperm-Ovum Interactions; D013094:Spermatozoa / Q000166:cytology*