Viewpoint 9--molecular structure of aqueous interfaces.
In this review we summarize recent progress in our understanding of the structure of aqueous interfaces emerging from molecular level computer simulations.  It is emphasized that the presence of the interface induces specific structural effects which, in turn, influence a wide variety of phenomena occurring near the phase boundaries.  At the liquid-vapor interface, the most probable orientations of a water molecule is such that its dipole moment lies parallel to the interface, one O-H bond points toward the vapor and the other O-H bond is directed toward the liquid.  The orientational distributions are broad and slightly asymmetric, resulting in an excess dipole moment pointing toward the liquid.  These structural preferences persist at interfaces between water and nonpolar liquids, indicating that the interactions between the two liquids in contact are weak.  It was found that liquid-liquid interfaces are locally sharp but broadened by capillary waves.  One consequence of anisotropic orientations of interfacial water molecules is asymmetric interactions, with respect to the sign of the charge, of ions with the water surface.  It was found that even very close to the surface ions retain their hydration shells.  New features of aqueous interfaces have been revealed in studies of water-membrane and water-monolayer systems.  In particular, water molecules are strongly oriented by the polar head groups of the amphiphilic phase, and they penetrate the hydrophilic head-group region, but not the hydrophobic core.  At infinite dilution near interfaces, amphiphilic molecules exhibit behavior different from that in the gas phase or in bulk water.  This result sheds new light on the nature of hydrophobic effect in the interfacial regions.  The presence of interfaces was also shown to affect both equilibrium and dynamic components of rates of chemical reactions.  Applications of continuum models to interfacial problems have been, so far, unsuccessful.  This, again, underscores the importance of molecular-level information about interfaces.
Pohorille
A
A
Department of Pharmaceutical Chemistry, University of California, San Francisco 94143, USA.
Wilson
M A
MA
D003198:Computer Simulation; D007474:Ion Exchange; D008051:Lipid Bilayers / Q000737:chemistry; D008958:Models, Molecular; D009010:Monte Carlo Method; D012996:Solutions / Q000737:chemistry; D013499:Surface Properties; D013500:Surface Tension; D014867:Water / Q000737:chemistry*
D008051:Lipid Bilayers; D012996:Solutions; D014867:Water