title: The technique of synoviorthesis.
abstract: Synoviorthesis (medical synovectomy) is a commonly utilized procedure employed in the management of recurrent intra-articular bleeds and secondary chronic synovitis in haemophilic patients. The procedure involves the intra-articular administration of an agent in order to induce fibrosis in the inflamed synovium so reducing the bleeding tendency. Such agents may either be chemical based (osmic acid, rifampicin) or radioactive (yttrium, gold or phosphorus). Whichever agent is employed care must be taken to avoid extra-articular complications (radiation burn and/or inflammatory reaction) as a result of extravasation or needle track contamination. The most frequently affected joints in haemophilia are the elbows, knees and the ankles, and to a lesser extent the shoulders and hips. This article outlines the techniques of injection of the five aforementioned joints, with details of the anatomical landmarks to perform the injections correctly. Injection of the elbows, knees and ankles may be carried out simply on an out-patient basis under local anaesthesia. However, it is advisable to perform injection of the shoulder or hip under radiographic control in order to ensure accurate placement. Very young children may require either sedation or a general anaesthetic. Strict asepsis is naturally a paramount requirement.
authors.affiliation: Service of Orthopaedics and Traumatology and Haemophilia Centre, La Paz University Hospital, Madrid, Spain. rmerchan@arrakis.es
authors.forename: E C
authors.initials: EC
authors.lastname: Rodriguez-Merchan
authors.forename: N J
authors.initials: NJ
authors.lastname: Goddard
mesh_terms: D001182:Arthroscopy / Q000379:methods*; D006395:Hemarthrosis / Q000150:complications / Q000209:etiology / Q000628:therapy; D006467:Hemophilia A / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007270:Injections, Intra-Articular; D011868:Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000627:therapeutic use; D013585:Synovitis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology
chemical_list: D011868:Radioisotopes; D019275:Radiopharmaceuticals