title: Marginal papular acrokeratodermas: no racial limitations for a clinical spectrum that responds to acitretin.
abstract: Marginal papular acrokeratoderma (MPA) encompasses a group of disorders that share crateriform, keratotic papules along the margins of the hands and feet. We report a unique case of a Philippino woman, with focal acral hyperkeratosis (FAH) associated with sensorineural hearing loss. The clinical phenotype of FAH (hereditary MPA without elastorrhexis) is expanded and the hypothesis of a racially limited disorder is weakened. Effective treatment of this embarrassing condition with acitretin is demonstrated.
authors.affiliation: Department of Dermatology, Derriford Hospital, Plymouth, UK. tlambiris@hotmail.com
authors.forename: A G
authors.initials: AG
authors.lastname: Lambiris
authors.forename: P L
authors.initials: PL
authors.lastname: Newman
mesh_terms: D017255:Acitretin / Q000627:therapeutic use*; D000169:Acrodermatitis / Q000150:complications / Q000188:drug therapy / Q000208:ethnology / Q000473:pathology*; D000328:Adult; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000150:complications; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D007642:Keratosis / Q000150:complications / Q000188:drug therapy / Q000208:ethnology / Q000473:pathology*
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin