title: Guideline for the management of heart failure caused by systolic dysfunction: Part I. Guideline development, etiology and diagnosis.
abstract: Over the past decade, the conceptual understanding of heart failure has changed significantly. Several large clinical trials have demonstrated that pharmacologic interventions can dramatically reduce the morbidity and mortality associated with heart failure. These trials have extended the therapeutic paradigm for treating heart failure beyond the goal of limiting congestive symptoms of volume overload. This two-part article presents an evidence-based guideline to assist primary care physicians in evaluating and treating patients with heart failure. Part I describes the new paradigm of heart failure and offers guidance for diagnostic testing. Part II presents a treatment guideline.
authors.affiliation: Department of Family Medicine, University of Michigan Medical School, Ann Arbor, USA. wchavey@umich.edu
authors.forename: W E
authors.initials: WE
authors.lastname: Chavey
authors.forename: C S
authors.initials: CS
authors.lastname: Blaum
authors.forename: B E
authors.initials: BE
authors.lastname: Bleske
authors.forename: R V
authors.initials: RV
authors.lastname: Harrison
authors.forename: S
authors.initials: S
authors.lastname: Kesterson
authors.forename: J M
authors.initials: JM
authors.lastname: Nicklas
mesh_terms: D019317:Evidence-Based Medicine; D006333:Heart Failure / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D017410:Practice Guidelines as Topic; D012720:Severity of Illness Index; D013318:Stroke Volume; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000503:physiopathology