Synthesis and structural study of pyrimidyl carbocyclic analogues of nucleosides based on cyclopentene rings.
A series of 1,2-disubstituted carbonucleoside analogues of pyrimidine and 5-halopyrimidines with the unsaturated carbocycle cyclopentene was synthesized. AIM theory was applied to analyse the conformational and electronic effects of 5-halogenation.
Terán
C
C
Vigo University, Vigo, Spain.
Gonzalez Moa
M J
MJ
Mosquera
R
R
Santana
L
L
D003517:Cyclopentanes / Q000138:chemical synthesis / Q000737:chemistry*; D008956:Models, Chemical; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry
D003517:Cyclopentanes; D011741:Pyrimidine Nucleosides