Oligomerization of deoxynucleoside-bisphosphate dimers:  template and linkage specificity.
Evidence is presented that a poly(U) template selectively favors the oligomerization of the activated, 3'-5' pyrophosphate-linked dimer pdAppdAp, in comparison with the 3'-3' and 5'-5' linked dimers.  In the absence of poly(U), the 5'-5' linked dimer is the most reactive, and chains are formed which are more than 60 monomer units in length.
Visscher
J
J
Laboratory for Exobiology, University of Nijmegen, The Netherlands.
van der Woerd
R
R
Bakker
C G
CG
Schwartz
A W
AW
D003853:Deoxyribonucleosides / Q000032:analysis / Q000138:chemical synthesis*; D019281:Dimerization; D011756:Diphosphates / Q000032:analysis / Q000737:chemistry; D019143:Evolution, Molecular; D009841:Oligonucleotides / Q000032:analysis / Q000138:chemical synthesis*; D010710:Phosphates / Q000032:analysis / Q000378:metabolism*; D011119:Polynucleotides / Q000032:analysis / Q000138:chemical synthesis; D013698:Templates, Genetic
D003853:Deoxyribonucleosides; D011756:Diphosphates; D009841:Oligonucleotides; D010710:Phosphates; D011119:Polynucleotides