title: Pancreatic mass caused by Mycobacterium tuberculosis with reduced drug sensitivity.
abstract: Pancreatic tuberculosis is a rare condition which should be considered in patients with a pancreatic mass, particularly if the patient is young, not jaundiced, from an area of high TB prevalence with a normal ERCP. We report a case of pancreatic tuberculosis due to Mycobacterium tuberculosis with reduced sensitivity to rifampicin and isoniazid, that was treated with rifabutin, ciprofloxacin, ethambutol and pyrazinamide following clinical failure of first-line therapy. The case presented illustrates the importance of obtaining material for culture and sensitivity testing in cases of suspected TB.
authors.affiliation: Regional Infectious Diseases Unit, Western General Hospital, Edinburgh EH4 2XU, UK.
authors.forename: G
authors.initials: G
authors.lastname: Small
authors.forename: D
authors.initials: D
authors.lastname: Wilks
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000494:pharmacology* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification; D010182:Pancreatic Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy*; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents