title: Modelling and simulation to support the design of a Dutch Protein Crystallization Facility.
abstract: This paper reports on the progress made in the development of the Netherlands Protein Crystallization Facility.  The facility allows two crystallization techniques:  Vapour diffusion and micro-dialysis.  The design and development is accompanied by a project in which it tried to model and simulate the events which occur during the vapour diffusion process within the crystallization cell.
authors.affiliation: Comprimo B.V., Amsterdam, The Netherlands.
authors.forename: F
authors.initials: F
authors.lastname: Eckhard
authors.forename: F
authors.initials: F
authors.lastname: Hegge
authors.forename: H P
authors.initials: HP
authors.lastname: Willemsen
mesh_terms: D000596:Amino Acids / Q000032:analysis; D003198:Computer Simulation; D018481:Convection; D003460:Crystallization; D004058:Diffusion; D004867:Equipment Design; D017551:Microdialysis / Q000295:instrumentation / Q000379:methods*; D008956:Models, Chemical; D009426:Netherlands; D011506:Proteins / Q000032:analysis / Q000737:chemistry*; D013696:Temperature; D014835:Volatilization; D014893:Weightlessness
chemical_list: D000596:Amino Acids; D011506:Proteins