title: Changes of brain response induced by simulated weightlessness.
abstract: The characteristics change of brain response was studied during 15 degrees head-down tilt (HDT) comparing with 45 degrees head-up tilt (HUT).  The brain responses evaluated included the EEG power spectra change at rest and during mental arithmetic, and the event-related potentials (ERPs) of somatosensory, selective attention and mental arithmetic activities. The prominent feature of brain response change during HDT revealed that the brain function was inhibited to some extent.  Such inhibition included that the significant increment of "40Hz" activity during HUT arithmetic almost disappeared during HDT arithmetic, and that the positive-potential effect induced by HDT presented in all kinds of ERPs measured, but the slow negative wave reflecting mental arithmetic and memory process was elongated.  These data suggest that the brain function be affected profoundly by the simulated weightlessness, therefore, the brain function change during space flight should be studied systematically.
authors.affiliation: Institute of Space Medico-Engineering, Beijing, China.
authors.forename: J
authors.initials: J
authors.lastname: Wei
authors.forename: G
authors.initials: G
authors.lastname: Yan
authors.forename: Z
authors.initials: Z
authors.lastname: Guan
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D004585:Electrooculography; D005071:Evoked Potentials; D005072:Evoked Potentials, Auditory; D005073:Evoked Potentials, Somatosensory; D018475:Head-Down Tilt / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D012677:Sensation / Q000502:physiology*; D013647:Task Performance and Analysis; D013977:Tibia / Q000294:innervation; D018474:Weightlessness Simulation