title: [Immunological aspects of the clinical pathogenesis of the inflammatory processes of the adnexa uteri].
abstract: Immunological aspects are highlighted of origination and course of chronic inflammatory process. The presented data show that a chronic inflammatory process originates and is maintained at the expense of disturbances in one or several components of the immune system realizing defence of the body against infections, and if these failures are not detected this can be due to inadequate methodological approaches or because of impossibility of identifying the existing inadequacy at the present stage of development of science. The existing congenital failures of immunity compensated by activation of synergic components of the system, with time and under exposure to adverse environmental factors, can bring about a cumulative effect leading to a phenotypical manifestation of the primary defect and to an increased infection case rate, including organs of the female reproductive system.
authors.forename: V N
authors.initials: VN
authors.lastname: Zaporozhan
authors.forename: V V
authors.initials: VV
authors.lastname: Bespoiasnaia
authors.forename: E V
authors.initials: EV
authors.lastname: Grushetskaia
mesh_terms: D002908:Chronic Disease; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D006801:Humans; D007154:Immune System Diseases / Q000150:complications / Q000151:congenital / Q000276:immunology; D007247:Infertility, Female / Q000209:etiology / Q000276:immunology; D000292:Pelvic Inflammatory Disease / Q000150:complications / Q000276:immunology* / Q000382:microbiology; D010641:Phenotype