Variation within the vat(E) allele of Enterococcus faecium isolates from retail poultry samples.
In a survey of retail meat samples, twelve quinupristin-dalfopristin-resistant (MICs, > or =4 mg/liter) Enterococcus faecium isolates that carried a vat(E) gene were recovered. DNA sequence comparison revealed five new variations in the vat(E) allele among 12 isolates, which were designated vat(E-4) through vat(E-8); two isolates had vat(E-1). There was no correlation between the number of base changes and the quinupristin-dalfopristin MIC.
Simjee
S
S
Division of Animal and Food Microbiology, Center for Veterinary Medicine, U.S. Food and Drug Administration, Laurel, MD 20708, USA. ssimjee@cvm.fda.gov
McDermott
P F
PF
Wagner
D D
DD
White
D G
DG
D000123:Acetyltransferases; D000483:Alleles; D000595:Amino Acid Sequence; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D016984:Enterococcus faecium / Q000235:genetics* / Q000302:isolation & purification; D014644:Genetic Variation; D008969:Molecular Sequence Data; D011202:Poultry Products / Q000382:microbiology*; D017386:Sequence Homology, Amino Acid
D001426:Bacterial Proteins; D000123:Acetyltransferases; C084756:streptogramin A acetyltransferase, Enterococcus faecium