[Studies on inhibiting activities of five antitumour drugs to human cancer cell in vitro with MTT assay].
The inhibiting activities of five antitumour drugs including "An ke su" to human cancer cell lines coming from 19 patients were measured in vitro with MTT assay, which can provide proper antitumor agents for clinical chemotherapy. The evaluation rate of medicine sensitivity is 89.47%, which is same as the result of clinical therapy. This method indicates the response of tumour cells to "An Ke Su" and other agents. Being simple, sensitive and rapid, it proves to be valuable in clinical therapy.
Yan
M
M
Dongfang Hospital, Shanghai Second Medical University, Shanghai 200120.
Lin
H
H
Shen
Y
Y
Wang
Q
Q
D000970:Antineoplastic Agents / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D009369:Neoplasms / Q000473:pathology*; D013778:Tetrazolium Salts; D013844:Thiazoles; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; D013778:Tetrazolium Salts; D013844:Thiazoles; C022616:thiazolyl blue