title: Microgravity simulations with human lymphocytes in the free fall machine and in the random positioning machine.
abstract: The purpose of this paper is to present the results obtained in our laboratory with both instruments, the FFM [free fall machine] and the RPM [random positioning machine], to compare them with the data from earlier experiments with human lymphocytes conducted in the FRC [fast rotating clinostat] and in space. Furthermore, the suitability of the FFM and RPM for research in gravitational cell biology is discussed.
authors.affiliation: Space Biology, ETH Zurich, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Schwarzenberg
authors.forename: P
authors.initials: P
authors.lastname: Pippia
authors.forename: M A
authors.initials: MA
authors.lastname: Meloni
authors.forename: G
authors.initials: G
authors.lastname: Cossu
authors.forename: M
authors.initials: M
authors.lastname: Cogoli-Greuter
authors.forename: A
authors.initials: A
authors.lastname: Cogoli
mesh_terms: D002478:Cells, Cultured; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006112:Gravitation; D006801:Humans; D008213:Lymphocyte Activation; D008940:Mitotic Index; D012399:Rotation; D013601:T-Lymphocytes / Q000502:physiology*; D014893:Weightlessness; D018474:Weightlessness Simulation / Q000295:instrumentation* / Q000379:methods