[Trans-endoscopic treatment of recurrent gastroduodenal ulcers by a combination therapy with lysozyme, molecular iodine and poly-iodides].
Pathogenesis substantiation and clinical efficiency of transendoscopic treatment of the patients with gastroduodenal ulcers relapse by lysozyme compound with molecular iodine and polyiodides are presented in this paper. The relapse of peptic ulcer was accompanied by lysozyme decrease and helicobacter's sowing increase in stomach and duodenal mucosa, as well as activity mucosa flora increase, especially in periulcer's region. This fact has drown near ulcer's defect and infected wound. Significant microbicidal and sorptional effects to the revealed strains of microorganisms, mucous membrane barrier properties increase and shortening of the peptic ulcer's scarring time on 8 days were demonstrated after transendoscopic treatment of the peptic ulcer with iodine lysozyme 3-4 times.
Bazlov
S N
SN
Chernin
V V
VV
Egorova
E N
EN
Strelets
E V
EV
Chervinets
V M
VM
D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D003131:Combined Modality Therapy; D004724:Endoscopy / Q000379:methods*; D005753:Gastric Mucosa / Q000382:microbiology; D006801:Humans; D007454:Iodides / Q000627:therapeutic use*; D009113:Muramidase / Q000627:therapeutic use*; D010437:Peptic Ulcer / Q000382:microbiology / Q000628:therapy*; D055502:Secondary Prevention
D000891:Anti-Infective Agents, Local; D007454:Iodides; D009113:Muramidase