title: Thermal synthesis and hydrolysis of polyglyceric acid.
abstract: Polyglyceric acid was synthesized by thermal condensation of glyceric acid at 80 degrees in the presence and absence of two mole percent of sulfuric acid catalyst.  The acid catalyst accelerated the polymerization over 100-fold and made possible the synthesis of insoluble polymers of both L- and DL-glyceric acid by heating for less than 1 day.  Racemization of L-glyceric acid yielded less than 1% D-glyceric acid in condensations carried out at 80 degrees C with catalyst for 1 day and without catalyst for 12 days.  The condensation of L-glyceric acid yielded an insoluble polymer much more readily than condensation of DL-glyceric acid.  Studies of the hydrolysis of poly-DL-glyceric acid revealed that it was considerably more stable under mild acidic conditions compared to neutral pH.  The relationship of this study to the origin of life is discussed.
authors.affiliation: The Salk Institute for Biological Studies, San Diego, CA 92138, USA.
authors.forename: A L
authors.initials: AL
authors.lastname: Weber
mesh_terms: D019418:Evolution, Chemical; D005985:Glyceraldehyde / Q000737:chemistry; D005988:Glyceric Acids / Q000032:analysis / Q000138:chemical synthesis* / Q000737:chemistry; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D000069497:Origin of Life; D011091:Polyesters / Q000138:chemical synthesis*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D012995:Solubility; D013464:Sulfuric Acids
chemical_list: D005988:Glyceric Acids; D011091:Polyesters; D011108:Polymers; D013464:Sulfuric Acids; C053491:polyglyceric acid; D005985:Glyceraldehyde; C042971:glyceric acid; C033158:sulfuric acid