title: [Schoenlein-Henoch purpura in adulthood (gastrointestinal manifestation and endoscopy)].
abstract: During a 15-year-period 62 adult patients were admitted with diagnosis of Schoenlein-Henoch purpura in our hospital. 25 female and 37 male patients ranged from 30-87 years (mean: 59.5 years) presenting with cutaneous, joint, renal and particularly abdominal involvement were investigated retrospectively. During the course of the disease, all patients developed purpuric rash (100 %), 14 (22,5 %) patients had joint symptoms and renal involvement occurred in 12 (19,3 %) patients. In this study, we discuss 15 (24 %) patients with gastrointestinal symptoms appearing in Henoch's purpura. Analysis of the gastrointestinal clinical features revealed: Abdominal pain 13 (86 %), massive colorectal bleeding 3 (20 %), occult blood loss 10 (66 %) vomiting 6 (40 %) and diarrhea in 3 (20 %) patients. Surgical consultation was obtained for 4 of the 15 patients and laparotomy was performed in 2 patients. All the patients underwent lower and upper endoscopic examination, in 3 cases the authors saw purpuric mucosal lesions in duodenum and in 8 patients were also found coin-like elevated lesions, additionally, biopsy from colonic lesions showed leukocytoclastic vasculitis. It is concluded that endoscopy may play a very important role in the diagnosis and treatment of Schoenlein-Henoch purpura.
authors.affiliation: Abteilung für Innere Medizin III, Gastroenterologie, Kálmán-Pándy-Krankenhaus, Semmelweis-Strasse 1, Gyula H-5700. novak@pandy.hu
authors.forename: J
authors.initials: J
authors.lastname: Novák
authors.forename: J
authors.initials: J
authors.lastname: Márki-Zay
authors.forename: Z
authors.initials: Z
authors.lastname: Csiki
authors.forename: J
authors.initials: J
authors.lastname: Sebesi
authors.forename: A
authors.initials: A
authors.lastname: Takáts
authors.forename: S
authors.initials: S
authors.lastname: Sipka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged