The role of signal systems in cell gravisensitivity.
Reception of physical environmental signals caused by alteration of the gravitation field leads to the shift of morpho-physiological cell characteristics.  The gravity influence on a cell may be direct or non direct, its extent varying in dependence of the cell model applied.  Direct influences are more pronounced in vitro, while non direct influences are usually expressed in the community of unicellular organisms (in vivo).  Gravity affects morphogenesis processes, such as locomotion, adhesion, intercellular contacts, etc.  At the same time, all the processes named are under control of cell integral systems of the signal transduction.  Minor disturbances in this system coming from the environment, due to amplification, may provide significant modulations of the signals.  So, studies of this system at the level of molecular cell reception is of great interest.  Results of flight and model experiments are discussed in the present manuscript.
Tairbekov
M G
MG
Institute of Biomedical Problems, Moscow, Russia.
D000818:Animals; D002118:Calcium / Q000502:physiology; D002450:Cell Communication / Q000502:physiology; D002468:Cell Physiological Phenomena; D003599:Cytoskeleton / Q000502:physiology; D019204:GTP-Binding Proteins / Q000502:physiology; D006112:Gravitation; D018466:Gravity Sensing / Q000502:physiology*; D010944:Plants; D015398:Signal Transduction / Q000502:physiology*; D013026:Space Flight; D014893:Weightlessness
D019204:GTP-Binding Proteins; D002118:Calcium