title: Robinlin: a novel bioactive homo-monoterpene from Robinia pseudoacacia L. (Fabaceae).
abstract: A bioactivity-directed fractionation of the ethanolic extracts of Robinia pseudoacacia L. (Fabaceae) afforded robinlin (1), a novel homo-monoterpene. The structure of 1 was elucidated by spectral analyses of the parent compound as well as its derivatives; 1 showed strong bioactivity in the brine shrimp lethality test (BST).
authors.affiliation: Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, School of Science, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: F
authors.initials: F
authors.lastname: Tian
authors.forename: C J
authors.initials: CJ
authors.lastname: Chang
authors.forename: J B
authors.initials: JB
authors.lastname: Grutzner
authors.forename: D E
authors.initials: DE
authors.lastname: Nichols
authors.forename: J L
authors.initials: JL
authors.lastname: McLaughlin
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D001156:Artemia / Q000187:drug effects*; D002470:Cell Survival / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D007887:Fabaceae / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D039821:Monoterpenes; D013729:Terpenes / Q000737:chemistry* / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D039821:Monoterpenes; D013729:Terpenes; C439164:robinlin