title: Hepatoprotective properties of aqueous extract from Pentaphylloides fruticosa during chronic toxic hepatitis.
abstract: Hepatoprotective properties of Pentaphylloides fruticosa L. aqueous extract were studied using rat model of chronic toxic hepatitis. The preparation normalized alanine aminotransferase activity and bilirubin concentration in the plasma. Aqueous extract of Pentaphylloides fruticosa produced a protective effect on microsomal metabolism of xenobiotics and lipid peroxidation activity in the plasma and microsomal liver fraction.
authors.affiliation: Institute of Clinical and Experimental Lymphology, Siberian Division of the Russian Academy of Medical Science, Novosibirsk. kolpakov@hospitall68.nsc.ru
authors.forename: M A
authors.initials: MA
authors.lastname: Kolpakov
authors.forename: O R
authors.initials: OR
authors.lastname: Grek
authors.forename: Y V
authors.initials: YV
authors.lastname: Bashkirova
authors.forename: M S
authors.initials: MS
authors.lastname: Lyubarskii
authors.forename: Y R
authors.initials: YR
authors.lastname: Ravilova
mesh_terms: D000818:Animals; D001663:Bilirubin / Q000378:metabolism; D002251:Carbon Tetrachloride / Q000633:toxicity; D006521:Hepatitis, Chronic / Q000188:drug therapy*; D015227:Lipid Peroxidation; D008099:Liver / Q000187:drug effects*; D008862:Microsomes, Liver / Q000378:metabolism; D010936:Plant Extracts / Q000627:therapeutic use*; D051381:Rats; D013997:Time Factors; D015262:Xenobiotics / Q000494:pharmacology
chemical_list: D010936:Plant Extracts; D015262:Xenobiotics; D002251:Carbon Tetrachloride; D001663:Bilirubin