title: Accumulation of stress protein 72 (HSP72) in muscle and spleen of goldfish taken into space.
abstract: Using Western blot analysis, here, we report the levels of HSP72 in several organs from goldfish which were taken into space on the NASA space shuttle. A remarkable accumulation of HSP72 was detected in muscle and spleen of those fish taken into space as compared with controls. These results suggested that the HSP72 induction is a kind of stress response at the molecular level introduced by the space environment consisting of microgravity and/or cosmic radiation as stressors.
authors.affiliation: Department of Biology, Nara Medical University, Kashihara, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ohnishi
authors.forename: K
authors.initials: K
authors.lastname: Tsuji
authors.forename: T
authors.initials: T
authors.lastname: Ohmura
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Nagaoka
authors.forename: A
authors.initials: A
authors.lastname: Takabayashi
authors.forename: A
authors.initials: A
authors.lastname: Takahahsi
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D007758:Ear, Inner / Q000601:surgery; D006054:Goldfish / Q000378:metabolism*; D050884:HSP72 Heat-Shock Proteins; D006360:Heat-Shock Proteins / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D012867:Skin / Q000378:metabolism; D013026:Space Flight; D013154:Spleen / Q000378:metabolism*; D013312:Stress, Physiological / Q000378:metabolism; D014893:Weightlessness
chemical_list: D050884:HSP72 Heat-Shock Proteins; D006360:Heat-Shock Proteins