Radioprotection of DNA by biochemical mechanisms.
The title of this presentation should be understood as having two facets: the preservation of genetic information and function by protecting the DNA from the deleterious effects of radiation by reducing the degree of damage, is one important task.  Yet another, which may be as important, is the utilization of biochemical entities whose function is to repair damages which have already been formed in DNA, thus enhancing the protection of living cells.
Riklis
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Nuclear Research Center, Negev, Beer Sheva, Israel.
D004999:Amifostine / Q000494:pharmacology; D000818:Animals; D002460:Cell Line; D002468:Cell Physiological Phenomena; D002477:Cells / Q000187:drug effects / Q000528:radiation effects*; D003543:Cysteamine / Q000494:pharmacology; D004249:DNA Damage / Q000187:drug effects / Q000502:physiology*; D011088:DNA Ligases / Q000502:physiology; D004260:DNA Repair / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D009536:Niacinamide / Q000494:pharmacology / Q000502:physiology; D011836:Radiation Tolerance / Q000187:drug effects / Q000502:physiology; D011837:Radiation-Protective Agents / Q000737:chemistry / Q000145:classification / Q000494:pharmacology*
D011837:Radiation-Protective Agents; D009536:Niacinamide; D003543:Cysteamine; D011088:DNA Ligases; D004999:Amifostine