title: Bovine pericardial patch angioplasty in carotid endarterectomy.
abstract: Patch angioplasty during carotid endarterectomy (CEA) has been shown to reduce the incidence of both early and late complications. Controversy continues, however, over the ideal patch material. Bovine pericardium (Vascu-Guard Biovascular Inc., Saint Paul, MN) offers an attractive alternative to other patch materials because of its handling and suturing characteristics that are similar to that of autogenous material. This study examines the perioperative and midterm results of bovine pericardial patch angioplasty during CEA. We studied 112 patients who underwent 129 CEAs with bovine pericardial patch angioplasty during an 18-month period. Data were collected regarding demographics, operative indications, perioperative complications, and the occurrence of late adverse outcomes based primarily on follow-up arterial duplex studies. Among this group there were 63 male (56%) and 49 female (44%) patients whose mean age was 71.8 +/- 9.1 years. In these patients there was the typical distribution of atherosclerotic risk factors. Seventy-four patients (66%) had symptomatic disease preoperatively and the remaining 38 patients (34%) were asymptomatic. Temporary cranial nerve palsy occurred in three patients (2%). There were no perioperative strokes, acute occlusions, bleeding episodes requiring reoperation, or deaths. The patients were followed up to 54 months postoperatively with a mean follow-up time of 41.7 +/- 4.4 months. During this period two patients (2%) developed three significant restenoses (70-99%). All required reoperation. There were no asymptomatic occlusions, infections, aneurysms, or rupture. These data demonstrate that bovine pericardial patch angioplasty during CEA is associated with a low incidence of both perioperative and midterm adverse outcomes.
authors.affiliation: Division of Vascular Surgery, Baylor University Medical Center, Dallas, Texas, USA.
authors.forename: B R
authors.initials: BR
authors.lastname: Grimsley
authors.forename: J K
authors.initials: JK
authors.lastname: Wells
authors.forename: G J
authors.initials: GJ
authors.lastname: Pearl
authors.forename: W V
authors.initials: WV
authors.lastname: Garrett
authors.forename: W P
authors.initials: WP
authors.lastname: Shutze
authors.forename: C M
authors.initials: CM
authors.lastname: Talkington
authors.forename: D R
authors.initials: DR
authors.lastname: Gable
authors.forename: B L
authors.initials: BL
authors.lastname: Smith
authors.forename: J E
authors.initials: JE
authors.lastname: Thompson
mesh_terms: D000368:Aged; D001705:Bioprosthesis; D001783:Blood Flow Velocity; D002343:Carotid Artery, Internal / Q000601:surgery; D016893:Carotid Stenosis / Q000503:physiopathology / Q000601:surgery; D016894:Endarterectomy, Carotid / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D010496:Pericardium / Q000637:transplantation*; D011183:Postoperative Complications