title: Step-by-step control by MALDI-TOF MS of an oligonucleotide synthesis on standard CPG solid-support.
abstract: MALDI-TOF mass spectrometry was used to monitor DNA solid-phase synthesis on long-chain alkylamine controlled-pore glass (LCAA-CPG) with a standard succinyl linker between the solid support and the growing oligonucleotide.
authors.affiliation: Lab. de Chimie Organique Biomoléculaire de Synthèse, UMR 5625 CNRS-UM2, Université Montpellier II, Place E. Bataillon, 34095, Montpellier, France.
authors.forename: A
authors.initials: A
authors.lastname: Meyer
authors.forename: F
authors.initials: F
authors.lastname: Debart
authors.forename: J L
authors.initials: JL
authors.lastname: Imbach
authors.forename: J J
authors.initials: JJ
authors.lastname: Vasseur
mesh_terms: D005898:Glass / Q000737:chemistry; D009841:Oligonucleotides / Q000138:chemical synthesis*; D009943:Organophosphorus Compounds / Q000737:chemistry; D017422:Sequence Analysis, DNA / Q000379:methods; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
chemical_list: D009841:Oligonucleotides; D009943:Organophosphorus Compounds; C434331:phosphoramidite