title: Compartment syndromes.
abstract: The compartment syndrome is defined as  a condition in which high pressure within a closed fascial space (muscle compartment) reduces capillary blood perfusion below the level necessary for tissue viability'.  This condition occurs in acute and chronic (exertional) forms, and may be secondary to a variety of causes.  The end-result of an extended period of elevated intramuscular pressure may be the development of irreversible tissue injury and Volkmann's contracture.  The goal of treatment of the compartment syndrome is the reduction of intracompartmental pressure thus facilitating reperfusion of ischaemic tissue and this goal may be achieved by decompressive fasciotomy.  Controversy exists regarding the critical pressure-time thresholds for surgical decompression and the optimal diagnostic methods of measuring intracompartmental pressures.  This paper will update and review some current knowledge regarding the pathophysiology, aetiology, diagnosis, and treatment of the acute compartment syndrome.
authors.affiliation: University of California, Division of Orthopaedics and Rehabilitation, San Diego.
authors.forename: S J
authors.initials: SJ
authors.lastname: Mubarak
authors.forename: R A
authors.initials: RA
authors.lastname: Pedowitz
authors.forename: A R
authors.initials: AR
authors.lastname: Hargens
mesh_terms: D002196:Capillaries / Q000502:physiology; D003161:Compartment Syndromes / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology*; D009132:Muscles / Q000098:blood supply / Q000502:physiology* / Q000503:physiopathology; D005082:Physical Exertion / Q000502:physiology; D011312:Pressure; D015427:Reperfusion Injury / Q000503:physiopathology