Inhibitory effects of aromatic herbs on lipid peroxidation and protein oxidative modification of mice brain homogenate by copper in vitro.
Several aromatic herbs were inferred to have inhibitory effects on the generation of oxygen free radicals. It has been demonstrated that free radicals produced by copper produce lipid peroxidation and protein oxidative modification in the brain. The results presented here showed that several aromatic herbs, Caryophylli flos, Cinnamomi cortex, Foeniculi fructus and Zedoariae rhizoma, have inhibitory effects on lipid peroxidation or protein oxidative modification of mice brain homogenate produced by copper in vitro.
Toda
S
S
Department of Pharmaceutical Science, Kansai College of Oriental Medicine, 2-22-1 Wakaba, Kumatori, Sen-nan, Osaka 590-04, Japan. toda@kansai.ac.jp
D000818:Animals; D001921:Brain / Q000187:drug effects; D003300:Copper / Q000037:antagonists & inhibitors / Q000494:pharmacology; D029001:Herbal Medicine; D066298:In Vitro Techniques; D007564:Japan; D015227:Lipid Peroxidation / Q000187:drug effects*; D019684:Magnoliopsida; D008297:Male; D051379:Mice; D008954:Models, Biological; D018384:Oxidative Stress; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D011506:Proteins / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism
D010936:Plant Extracts; D011506:Proteins; D017382:Reactive Oxygen Species; D003300:Copper