Antimicrobial susceptibilities of clinical Desulfovibrio isolates.
The antimicrobial susceptibilities of 16 clinical isolates of Desulfovibrio spp. were determined. All or most isolates were susceptible to imipenem (MIC(90) [MIC at which 90% of the isolates tested were inhibited], 0.5 microg/ml), metronidazole (MIC(90), 0.25 microg/ml), clindamycin (MIC(90), 4 microg/ml), and chloramphenicol (MIC(90), 16 microg/ml) but were resistant or intermediate to penicillin G (MIC(90), 64 microg/ml), piperacillin (MIC(90), 256 microg/ml), piperacillin-tazobactam (MIC(90), 256 microg/ml), cefoxitin (MIC(90), >256 microg/ml), and cefotetan (MIC(90), 64 microg/ml). Among isolates with decreased susceptibility to beta-lactams (n = 15), only six were beta-lactamase positive and susceptible to amoxicillin-clavulanate and ticarcillin-clavulanate.
Lozniewski
A
A
Laboratoire de Bactériologie, Hôpital Central, CHU, 29 Avenue du Maréchal de Lattre de Tassigny, 54035 Nancy Cedex, France.
Labia
R
R
Haristoy
X
X
Mory
F
F
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002701:Chloramphenicol / Q000494:pharmacology; D002981:Clindamycin / Q000494:pharmacology; D003901:Desulfovibrio / Q000187:drug effects*; D004338:Drug Combinations; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010400:Penicillin G / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D008795:Metronidazole; D002981:Clindamycin; D002701:Chloramphenicol; D015378:Imipenem; D010400:Penicillin G