Preliminary results of Cytos 2 experiment.
Cytos 2 experiment, carried out during the French-Soviet manned flight (July 1982), has studied the antibiotics sensitivity of bacteria cultivated in vitro during the orbital flight. The results show an increase of the antibiotics resistance and a larger thickness of the cellular envelope for the inflight cells. The increase of antibiotics resistance can be related to a stimulating effect of space on the cell growth rate or to changes of the cellular envelope structure.
Tixador
R
R
Groupe de Recherches, Biologiques Spatiales, Universite Paul Sabatier, Toulouse, France.
Richoilley
G
G
Gasset
G
G
Planel
H
H
Moatti
N
N
Lapchine
L
L
Enjalbert
L
L
Raffin
J
J
Bost
R
R
Zaloguev
S N
SN
Bragina
M P
MP
Moroz
A F
AF
Antsiferova
N G
NG
Kirilova
F M
FM
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003091:Colistin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects* / Q000648:ultrastructure; D007612:Kanamycin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010068:Oxacillin / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology; D013026:Space Flight; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000648:ultrastructure; D014893:Weightlessness
D000900:Anti-Bacterial Agents; D010406:Penicillins; D007612:Kanamycin; D004917:Erythromycin; D002701:Chloramphenicol; D010068:Oxacillin; D003091:Colistin