Meningeal allografts of the 6-day-old rat pineal: a model for a pineal deprived of intracerebral innervation.
Pineals from 6-day-old rats were transplanted into an incised bed of the parietal cortex of adult rats, of which 29 survived 4-5 weeks after transplantation. The pinealocytes and capillaries in the grafts were comparable in structure to those in the control. Grafts were demarcated from the host cortical tissue by a double, meninx plus gland-capsule sheath through which no nerve ingrowth was seen into the graft from the host brain. On the other hand, sympathetic nerves originating from the cervical ganglia reached the grafted pineal along the perivascular spaces of blood vessels, as is the case in situ. On this basis. the present meningeal graft is thought to be a model of the pineal gland surviving without its intracerebral neural control.
Zsarnovszky
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A
Department of Anatomy and Histology, Szent István University, Faculty of Veterinary Science, Budapest, Hungary.
Szalay
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Hajos
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F
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D003714:Denervation; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D008854:Microscopy, Electron; D010296:Parietal Lobe / Q000473:pathology / Q000601:surgery*; D010870:Pineal Gland / Q000473:pathology / Q000637:transplantation*; D051381:Rats; D017208:Rats, Wistar; D014184:Transplantation, Homologous