Inhalation therapy: new delivery systems.
The objective of this article is to provide an overview of recent advances in inhalation drug delivery. Problems, advantages, limitations, and developments encountered by different inhalation devices and the agents used in these for the purpose of pulmonary delivery are discussed. A critical appraisal is presented and finally the future directions especially in research of the inhaled therapeutics and aerosols are described.
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Rush-Presbyterian-St. Luke's Center, Rush University, Department of Pharmacology, Chicago, Illinois 60612-3515, USA.
D000280:Administration, Inhalation; D000336:Aerosols; D000818:Animals; D019540:Area Under Curve; D001682:Biological Availability; D002626:Chemistry, Pharmaceutical; D016503:Drug Delivery Systems; D005260:Female; D006207:Half-Life; D006801:Humans; D008657:Metabolic Clearance Rate; D009297:Nasal Mucosa / Q000378:metabolism*; D010599:Pharmacokinetics
D000336:Aerosols