[Specific anti-Yersinia G- and M-antibodies in healthy blood donors and in patients with alimentary intoxication].
The work deals with the results of determination of specific antibodies in blood donors of Moscow and Tula and in patients with alimentary toxicoinfection, made with the use of enzyme immunoassay on the basis of Yersinia enterocolitica lipopolysaccharides (LPS), serovars O3 and O9. The sera of patients with alimentary toxicoinfection were found to yield positive reactions with Y. enterocolitica LPS in 35.9% of cases (the number of such reactions obtained with blood donor sera was 3 times less). The presence of cross reactions between Y. enterocolitica LPS and the microsomal antigens of the thyroid gland was established. A high detection rate of antibodies to the microsomal antigens of the thyroid gland among blood donors of Tula was registered.
Lebed'
N E
NE
Mechnikov Researh Institute for Vaccines and Sera, Moscow, Russia.
Poddubikov
A V
AV
Iastrebova
N E
NE
Vaneeva
N P
NP
Bogacheva
E A
EA
Zakharova
N E
NE
D000907:Antibodies, Bacterial / Q000097:blood*; D000918:Antibody Specificity; D001782:Blood Donors; D003429:Cross Reactions; D005517:Foodborne Diseases / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D008070:Lipopolysaccharides / Q000276:immunology; D008861:Microsomes / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology / Q000648:ultrastructure; D015008:Yersinia enterocolitica / Q000276:immunology*
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008070:Lipopolysaccharides