title: Synthesis and evaluation of antiviral activity of higher homologues of xylo-carbocyclic nucleosides.
abstract: New carbocyclic nucleosides with purine (compounds 3a and 3b), and 8-azapurine (compounds 3c and 3d) as base were prepared and assayed for in vitro activity.
authors.affiliation: Depto. Química Orgánica, Universidad de Santiago, E-15706, Santiago de Compostela, Spain.
authors.forename: O
authors.initials: O
authors.lastname: Caamaño
authors.forename: M J
authors.initials: MJ
authors.lastname: Figueira
authors.forename: F
authors.initials: F
authors.lastname: Fernández
authors.forename: M D
authors.initials: MD
authors.lastname: García
authors.forename: M I
authors.initials: MI
authors.lastname: Nieto
authors.forename: E
authors.initials: E
authors.lastname: De Clercq
authors.forename: J
authors.initials: J
authors.lastname: Balzarini
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D008968:Molecular Conformation; D011684:Purine Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology*; D011687:Purines / Q000138:chemical synthesis / Q000494:pharmacology; D014994:Xylose / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D000998:Antiviral Agents; D011684:Purine Nucleosides; D011687:Purines; C015008:triazolopyrimidinone; D014994:Xylose