title: Relative biological effectiveness and microdosimetry of a mixed energy field of protons up to 200 MeV.
abstract: We have studied radiation effects utilizing the new 250 MeV Synchrotron at Loma Linda University Medical Center. In this paper we present the data collected for the survival of Chinese hamster lung (V79) cells, that were irradiated with a beam of mixed energy protons up to 200 MeV. The RBE for protons, when compared to 60Co gamma rays, ranged from a low of 1.2 at the high energy portion of the field to 1.3+ at the low energy portion of the field. These results are consistent with the measured lineal energy (microdosimetric) spectra.
authors.affiliation: East Carolina University, Greenville, NC 27858, USA.
authors.forename: J B
authors.initials: JB
authors.lastname: Robertson
authors.forename: J M
authors.initials: JM
authors.lastname: Eaddy
authors.forename: J O
authors.initials: JO
authors.lastname: Archambeau
authors.forename: G B
authors.initials: GB
authors.lastname: Coutrakon
authors.forename: D W
authors.initials: DW
authors.lastname: Miller
authors.forename: M F
authors.initials: MF
authors.lastname: Moyers
authors.forename: J V
authors.initials: JV
authors.lastname: Siebers
authors.forename: J M
authors.initials: JM
authors.lastname: Slater
authors.forename: J F
authors.initials: JF
authors.lastname: Dicello
mesh_terms: D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects; D002478:Cells, Cultured / Q000528:radiation effects*; D003037:Cobalt Radioisotopes; D006224:Cricetinae; D005720:Gamma Rays; D018499:Linear Energy Transfer; D010315:Particle Accelerators; D019047:Phantoms, Imaging; D011522:Protons; D011829:Radiation Dosage; D012062:Relative Biological Effectiveness
chemical_list: D003037:Cobalt Radioisotopes; D011522:Protons