title: The use of lymphoscintigraphy and PET in the management of head and neck melanoma.
abstract: OBJECTIVE
  Lymphoscintigraphy with sentinel node dissection and 18 fluoro-2-deoxyglucose positron emission tomography (PET) are being used independently in the management of many intermediate and thick melanomas of the head and neck. We report a series of patients with melanoma of the head and neck with Breslow depths greater than 1.0 mm and clinically negative regional nodes that were evaluated prospectively with PET and lymphoscintigraphy.
  
  
  METHODS
  Between July 1, 1998 and December 30, 2000 PET scans were obtained preoperatively on 18 patients undergoing resection of head and neck melanoma. Lymphoscintigraphy and sentinel node dissection was performed. Resection of the primary lesion was then carried out with adequate margins and the defects were reconstructed.
  
  
  RESULTS
  Sentinel node(s) were found in 17/18 patients (94.4%); 5/18 (27.8%) of cases had metastases. PET detected nodal metastasis preoperatively in 3 patients (16.7%), one of which had a positive sentinel node dissection.
  
  
  CONCLUSIONS
  PET and lymphoscintigraphy offer complimentary ways of evaluation for metastatic melanoma.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, St. Louis University Health Sciences Center, Missouri, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Kokoska
authors.forename: G
authors.initials: G
authors.lastname: Olson
authors.forename: P R
authors.initials: PR
authors.lastname: Kelemen
authors.forename: S
authors.initials: S
authors.lastname: Fosko
authors.forename: F
authors.initials: F
authors.lastname: Dunphy
authors.forename: V J
authors.initials: VJ
authors.lastname: Lowe
authors.forename: B C
authors.initials: BC
authors.lastname: Stack
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D009669:Nose Neoplasms / Q000000981:diagnostic imaging; D021701:Sentinel Lymph Node Biopsy; D014055:Tomography, Emission-Computed