Gelatinous transformation of bone marrow from a starch-free diet.
Gelatinous marrow transformation is characterized by marrow hypoplasia, fat atrophy, and gelatinous material deposition, and usually develops as a hematologic complication of chronic wasting disorders. Most of the cases associated with severe nutritional deficiency were seen in anorexia nervosa due to a depletion of protein or fat. This report describes a case of gelatinous transformation attributed to a specific restriction of carbohydrates in diet. The hematologic deficiency was eventually recovered after the patient resumed a regular starch-containing diet. This brief report illustrates the potential side effect of the compulsive dietary behavior on the hematologic system.
Wang
C
C
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, University of Toronto, Toronto, Canada. cwang@mtsinai.on.ca
Amato
D
D
Fernandes
B
B
D000328:Adult; D001853:Bone Marrow / Q000473:pathology*; D004032:Diet / Q000009:adverse effects*; D005780:Gelatin; D006801:Humans; D008297:Male; D013213:Starch / Q000008:administration & dosage*
D005780:Gelatin; D013213:Starch