title: [Diagnostic significance of de Ritis coefficient and leukocytic intoxication index in victims with open fractures of mandible].
abstract: Despite great differences in the patients with complicated and uncomplicated mandibular fractures, the activity of serum transaminases reflects the severity of damage to osteomuscular tissue and time course of development of inflammatory reaction. The leukocytic intoxication index (LII) characterizes stress reaction of the blood system during the first hours and development of inflammation in later periods of the posttraumatic period. The ratio of de Ritis coefficient/LII indicates the level of endogenous intoxication, cell membrane permeability, development and time course of the inflammatory process. Hence, these parameters are diagnostically and prognostically significant for predicting the outcome of the posttraumatic period and serve as criteria for development of optimal treatment algorithms.
authors.forename: N V
authors.initials: NV
authors.lastname: Novosiadlaia
authors.forename: R A
authors.initials: RA
authors.lastname: Belovolova
authors.forename: V E
authors.initials: VE
authors.lastname: Novgorodskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D017102:Fracture Healing / Q000502:physiology; D005597:Fractures, Open / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000209:etiology; D007958:Leukocyte Count; D008297:Male; D008337:Mandibular Fractures / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D008875:Middle Aged; D000637:Transaminases / Q000097:blood*
chemical_list: D000637:Transaminases