[Technique and results of CT-guided percutaneous bone biopsy].
OBJECTIVE
The aim of the study was to evaluate the feasibility and results of CT-guided percutaneous bone biopsy (PBB) of unknown bone lesions in a representative number of patients.


METHODS
In 92 patients (100 biopsies) with different bone lesions CT-guided PBB was performed.


RESULTS
The rate of technical success, defined as a successful retrieval of a sufficient tissue sample which then was sent for histological evaluation, was 89% (89/100 biopsies). The diagnostic accuracy was defined as a clinically useful histological result and was obtained in 80% (80/100 biopsies). Minor complications (minimal bleedings) occurred in 3% of all biopsies, no special therapy was necessary. Osteolytic lesions (92%) were classified more accurately by PBB than osteoplastic (80%) or mixed lesions (67%). Considering the anticipated dignity of the lesions prior to PBB, the suspected malignant bone lesions had a better diagnostic accuracy of 82% than the suspected benign bone lesions with an accuracy of 50%.


CONCLUSIONS
Due to its universal availability combined with a low risk and a high diagnostic value the PBB of unknown bone lesions can be regarded as a valuable diagnostic tool. However, leave-me-alone lesions should be excluded.
Duda
S H
SH
Abteilung für Radiologische Diagnostik, Radiologische Universitätsklinik, Eberhard-Karls-Universität Tübingen. stephan.duda@med.uni-tuebingen.de
Johst
U
U
Krahmer
K
K
Pereira
P
P
König
C
C
Schäfer
J
J
Huppert
P
P
Schott
U
U
Böhm
P
P
Claussen
C D
CD
D001707:Biopsy, Needle / Q000379:methods*; D001847:Bone Diseases / Q000175:diagnosis / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis / Q000473:pathology; D014057:Tomography, X-Ray Computed