A mathematical model of the cardiovascular response to +Gz acceleration.
The cardiovascular system is the limiting factor for human tolerance to positive Gz (head-to-foot) acceleration induced during maneuvers of fighter aircrafts.  Safe handling of modern fighter aircrafts with higher acceleration capabilities require the use of countermeasures such as a G-suit or breathing at a positive pressure.  A better understanding of the mechanisms involved in the cardiovascular response to +Gz acceleration would help improve the design and application of protective measures.  This paper presents a simple mathematical model of the cardiovascular system which incorporates arterial and cardiopulmonary baroreflexes, left ventricular-peripheral circulation interaction and decreased venous return.  This model is capable of reproducing observed overall cardiovascular response to +Gz acceleration.
Melchior
F M
FM
Laboratoire de Médecine Aérospatiale, Centre d'Essais en Vol, Brétigny, France.
Srinivasan
R S
RS
Ossard
G
G
Clère J-M
D000054:Acceleration; D017704:Baroreflex / Q000502:physiology*; D001794:Blood Pressure; D002498:Centrifugation; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D013318:Stroke Volume / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*