title: CD40 pathway blockade as an approach to immunotherapy.
authors.affiliation: Biogen, Inc.
authors.forename: L C
authors.initials: LC
authors.lastname: Burkly
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology / Q000627:therapeutic use*; D017951:Antigen Presentation; D000938:Antigen-Presenting Cells / Q000276:immunology; D001161:Arteriosclerosis / Q000276:immunology / Q000628:therapy; D001327:Autoimmune Diseases / Q000276:immunology / Q000628:therapy; D019013:CD40 Antigens / Q000235:genetics / Q000276:immunology; D023201:CD40 Ligand / Q000235:genetics / Q000276:immunology* / Q000502:physiology; D015815:Cell Adhesion Molecules / Q000096:biosynthesis / Q000235:genetics; D002450:Cell Communication / Q000276:immunology; D002633:Chemotaxis / Q000502:physiology; D004195:Disease Models, Animal; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology / Q000628:therapy; D005786:Gene Expression Regulation; D006084:Graft Rejection / Q000517:prevention & control; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000276:immunology; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D008213:Lymphocyte Activation / Q000276:immunology; D008211:Lymphocyte Cooperation / Q000276:immunology*; D008252:Macaca fascicularis; D051379:Mice; D018448:Models, Immunological; D005810:Multigene Family; D011658:Pulmonary Fibrosis / Q000276:immunology / Q000628:therapy; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D017154:Stromal Cells / Q000166:cytology / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D014777:Virus Diseases / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D019013:CD40 Antigens; D015815:Cell Adhesion Molecules; D011948:Receptors, Antigen, T-Cell; D023201:CD40 Ligand