title: Danazol therapy in factor X deficiency.
abstract: Factor X (FX) deficiency is a rare coagulation disorder that usually presents with bleeding manifestations and is treated with fresh frozen plasma or prothrombin complex concentrates. We report a case of FX deficiency in which the patient presented with bleeding as well as thrombosis. The patient responded to Danazol and relapsed when the drug was stopped. The occurrence of thrombosis in FX deficiency and the role of Danazol in coagulopathies are reviewed.
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Mukhopadhyay
authors.forename: R
authors.initials: R
authors.lastname: Saxena
authors.forename: R
authors.initials: R
authors.lastname: Kashyap
authors.forename: V P
authors.initials: VP
authors.lastname: Choudhry
mesh_terms: D000328:Adult; D003613:Danazol / Q000008:administration & dosage* / Q000627:therapeutic use; D005171:Factor X Deficiency / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D011877:Radionuclide Imaging; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology
chemical_list: D003613:Danazol