Regulatory T cells and allergic asthma.
Because of the characteristic airway inflammation observed in allergic asthma, the pathogenesis of this disease may be due, in part, to a lack of anti-inflammatory and immune suppressive mechanisms. Here, we discuss the possible involvement and therapeutic use of T regulatory cells and their soluble factors in this multifactorial disease.
Yssel
H
H
Inserm U454, CHU Arnaud de Villeneuve, 371 avenue Doyen Gaston Giraud, 34295 Montpellier cedex 5, France. yssel@montp.inserm.fr
Lécart
S
S
Pène
J
J
D000818:Animals; D001249:Asthma / Q000276:immunology*; D015536:Down-Regulation; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000502:physiology*