[Effect of the enteric sorbent noolit on the psychoemotional status in mice].
The enterosorbent noolit (representing a mineral matrix base with immobilized lithium and silicon compounds) significantly affects the psychoemotional state of mice with depression model induced by prolonged social emotional stress. Noolit administration produces a pronounced anxiolytic and antidepressant effect and reduced the level of behavioral deficiency in the test animals.
Borodin
Iu I
IuI
Institute of Clinical and Experimental Lymphology, Siberian Division, Russian Academy of Medical Sciences, ul. Timakova, 2, Novosibirsk, 630117 Russia.
Rachkovskaia
L N
LN
Tenditnik
M V
MV
Shurlygina
A V
AV
Kudriavtseva
N N
NN
Trufakin
V A
VA
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D003863:Depression / Q000209:etiology / Q000523:psychology / Q000628:therapy*; D016061:Enterosorption / Q000379:methods*; D008094:Lithium / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008903:Minerals; D012825:Silicon / Q000627:therapeutic use; D013315:Stress, Psychological / Q000150:complications
D008903:Minerals; D008094:Lithium; D012825:Silicon