title: Human parvovirus B19 in cord blood of premature infants.
abstract: We investigated whether intrauterine parvovirus B19 infection is associated with premature birth by evaluating parvovirus B19 antibodies and DNA in umbilical cord blood from 76 premature infants. We performed enzyme-linked immunoadsorbent (ELISA) and polymerase chain reaction (PCR) assays to detect B19-specific IgM antibodies and parvovirus DNA. No parvovirus DNA was detected in cord blood sera, and no sample was positive for anti-parvovirus B19 IgM antibodies. Parvovirus appears unlikely to lead to premature birth.
authors.affiliation: Department of Pediatrics, Yamaguchi University School of Medicine, Yamaguchi, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Koga
authors.forename: T
authors.initials: T
authors.lastname: Matsuoka
authors.forename: K
authors.initials: K
authors.lastname: Katayama
authors.forename: K
authors.initials: K
authors.lastname: Takeda
authors.forename: M
authors.initials: M
authors.lastname: Nakata
authors.forename: M
authors.initials: M
authors.lastname: Sase
authors.forename: H
authors.initials: H
authors.lastname: Kato
authors.forename: S
authors.initials: S
authors.lastname: Furukawa
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D004279:DNA, Viral / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005312:Fetal Blood / Q000276:immunology / Q000821:virology*; D005315:Fetal Diseases / Q000821:virology; D005865:Gestational Age; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007231:Infant, Newborn; D007234:Infant, Premature; D007752:Obstetric Labor, Premature / Q000209:etiology; D010322:Parvoviridae Infections / Q000150:complications / Q000821:virology; D016732:Parvovirus B19, Human / Q000276:immunology / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D011247:Pregnancy
chemical_list: D000914:Antibodies, Viral; D004279:DNA, Viral; D007070:Immunoglobulin A; D007075:Immunoglobulin M