[Bone marrow hematopoiesis in polymer composite implants in long-term bone marrow cultures].
The morphological composition of cells on implants made of different composition materials was studied on the model of long-term bone marrow cultures at cultivation for 28 days. Three samples of materials were investigated: polymethyl methacrylate (PMMC), PMMC with hydroxyapatite (HA) and PMMC with HA and subsequent processing with supercritical carbon dioxide. A gradual rise in total number of cells was observed on the implants for 4 weeks as well as increasing number of stromal and hemopoietic cells. With increasing time of cultivation the share of stromal cells was growing while the percent of hemopoietic cells fell. The greater number of hemopoietic cells was observed on the samples of the implants made from composites containing HA vs implants made from the initial PMMC.
Volozhin
A I
AI
Pesin
R S
RS
Lebedev
V G
VG
Popov
V K
VK
Roginskiĭ
V V
VV
Deshevoĭ
Iu B
IuB
D000818:Animals; D001672:Biocompatible Materials; D001854:Bone Marrow Cells / Q000166:cytology*; D003188:Composite Resins; D046508:Culture Techniques; D017886:Durapatite; D006410:Hematopoiesis; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D019904:Polymethyl Methacrylate; D013997:Time Factors
D001672:Biocompatible Materials; D003188:Composite Resins; D019904:Polymethyl Methacrylate; D017886:Durapatite