title: Novel nucleosides with vinyl fluoride or vinyl bromide moiety as open-chain analogs of neplanocin A.
abstract: Novel nucleosides with vinyl fluoride and vinyl bromide were designed, synthesized and evaluated their antiviral activities against poliovirus, HSV, HIV, and HBV.
authors.affiliation: College of Pharmacy, Sookmyung Women's University, Seoul 140-742, Korea.
authors.forename: M H
authors.initials: MH
authors.lastname: Choi
authors.forename: C K
authors.initials: CK
authors.lastname: Lee
authors.forename: L S
authors.initials: LS
authors.lastname: Jeong
authors.forename: M W
authors.initials: MW
authors.lastname: Chun
authors.forename: H D
authors.initials: HD
authors.lastname: Kim
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009705:Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology*; D014753:Vinyl Compounds / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D009705:Nucleosides; D014753:Vinyl Compounds; C016829:vinyl fluoride; C031096:neplanocin A; C003763:vinyl bromide; D000241:Adenosine