Calcifying lupus panniculitis in a patient with subacute cutaneous lupus erythematosus: response to diltiazem and chloroquine.
Lupus panniculitis has been reported to occur with a frequency of 2-3% in patients with lupus erythematosus (LE). It is most often reported in association with lesions of discoid LE. We describe a patient with subacute cutaneous LE who developed calcified nodules that were histopathologically consistent with lupus panniculitis. She was treated with a combination of chloroquine and diltiazem with a good therapeutic response. The addition of diltiazem may be beneficial in patients with calcified nodules of lupus panniculitis.
Morgan
K W
KW
Department of Medicine, University of Louisville School of Medicine, Kentucky, USA.
Callen
J P
JP
D000328:Adult; D001707:Biopsy, Needle; D002114:Calcinosis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D002738:Chloroquine / Q000008:administration & dosage*; D004110:Diltiazem / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D015435:Panniculitis, Lupus Erythematosus / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
D002738:Chloroquine; D004110:Diltiazem