title: Bone ultrastructural changes in Bion 11 rhesus monkeys.
abstract: Iliac crest biopsies of Bion 11 monkeys were examined by electron microscopy. The flight samples contained a large number of inactive osteoblasts. Together with ultrastructural changes of the rough endoplasmic reticulum and the Golgi complex, the predominance of inactive osteoblasts pointed to a lower rate of specific syntheses.  Some osteoblasts were transformed to fibroblast-like cells. It was found that osteogenesis declined, osteoid mineralization changed, and fibrotic zones developed.
authors.affiliation: Schmalhauzen Institute of Zoology, Ukrainian Academy of Sciences, Kiev, Ukraine.
authors.forename: N V
authors.initials: NV
authors.lastname: Rodionova
authors.forename: I M
authors.initials: IM
authors.lastname: Shevel
authors.forename: V S
authors.initials: VS
authors.lastname: Oganov
authors.forename: V E
authors.initials: VE
authors.lastname: Novikov
authors.forename: O E
authors.initials: OE
authors.lastname: Kabitskaya
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001842:Bone and Bones / Q000166:cytology / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D007085:Ilium / Q000166:cytology / Q000648:ultrastructure*; D008253:Macaca mulatta; D008297:Male; D008854:Microscopy, Electron; D010006:Osteoblasts / Q000166:cytology / Q000648:ultrastructure*; D010011:Osteocytes / Q000166:cytology / Q000648:ultrastructure*; D010012:Osteogenesis / Q000502:physiology; D013026:Space Flight; D014893:Weightlessness