Studies on atrophic change of soleus muscle and its countermeasures in suspended rat.
In the environment of microgravity, the disused atrophy of skeletal muscle, especially leg's muscle, would occur.  The three purposes of this study were:  1.  To observe the dynamic changes of disused atrophy of skeletal muscle under simulated weightlessness; 2.  To approach the mechanism of disused atrophy of muscle; 3.  To approach the countermeasures for reducing the degree of atrophy of muscle.
Zhuang
X C
XC
Institute of Space Medico-Engineerin, Beijing, China.
Sun
Y Z
YZ
Cui
J
J
Zhu
J M
JM
Jiang
C
C
Xiang
Q L
QL
Li
C S
CS
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology; D004558:Electric Stimulation; D018475:Head-Down Tilt; D006614:Hindlimb; D007103:Immobilization; D007259:Infrared Rays; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D018657:Muscle Fibers, Slow-Twitch / Q000502:physiology; D009124:Muscle Proteins / Q000032:analysis; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000473:pathology / Q000503:physiopathology*; D009133:Muscular Atrophy / Q000473:pathology / Q000503:physiopathology* / Q000517:prevention & control; D009929:Organ Size; D051381:Rats; D017207:Rats, Sprague-Dawley; D012039:Regional Blood Flow / Q000187:drug effects / Q000528:radiation effects; D013623:Tail; D013997:Time Factors; D018544:Weightlessness Countermeasures; D018474:Weightlessness Simulation
D004365:Drugs, Chinese Herbal; D009124:Muscle Proteins