title: Is there "cardiovascular drift" during and after simulated orthostasis in humans?
abstract: This study investigates the time course of hemodynamic variables during and after simulated orthostasis (lower body suction at 55mmHg for 30 mins: LBNP-55).  Individual strategies of blood pressure defense could be observed; LBNP-55 increased heart rate and reduced stroke volume, but was non-hypotensive.  During 20 minutes post-LBNP, heart rate was decreased as well as stroke volume index below pre-LBNP values.  The reduced cardiac index together with unchanged mean arterial pressure gave a highly significant increase of peripheral resistance after LBNP.  The validity of stroke volume results under the experimental conditions given needs to be clarified.
authors.affiliation: University of Graz, Department of Physiology, Austria.
authors.forename: H G
authors.initials: HG
authors.lastname: Hinghofer-Szalkay
authors.forename: Z
authors.initials: Z
authors.lastname: László
authors.forename: A
authors.initials: A
authors.lastname: Rössler
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008150:Lower Body Negative Pressure / Q000009:adverse effects*; D008297:Male; D013318:Stroke Volume / Q000502:physiology*; D014655:Vascular Resistance / Q000502:physiology