title: Biological stereoselective reduction of 3,3,5-trimethylcyclohexanone by Glomerella cingulata.
abstract: The microbial transformation of 3,3,5-trimethylcyclohexanone was investigated using the plant pathogenic fungus, Glomerella cingulata. With this organism 3,3,5-trimethylcyclohexanone gave the corresponding cis- and trans-3,3,5-trimethylcyclohexanols with the ratio of 20:1 forming the cis-isomer highly stereoselectively, upon 5 days incubation together with 3,3,5-trimethyl-2-cyclohexen-1-one (isophrone) as a minor product.
authors.affiliation: Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka-shi, Osaka 577-8502, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Okamura
authors.forename: H
authors.initials: H
authors.lastname: Kameoka
authors.forename: M
authors.initials: M
authors.lastname: Miyazawa
mesh_terms: D001203:Ascomycota / Q000378:metabolism*; D001711:Biotransformation; D003512:Cyclohexanones / Q000378:metabolism*; D013237:Stereoisomerism
chemical_list: D003512:Cyclohexanones; C438457:3,3,5-trimethylcyclohexanone