[Effect of daflon on the transcapillary fluid exchange in hindlimbs of anesthesized Wistar rats].
The effect of daflon administration (100 mg/kg/day, p.o., over 8 days) upon the transcapillary fluid shift in the hind extremities of narcotized rats was studied. The effect was evaluated by the arterio-venous difference of the blood density (orthostatic versus antiorthostatic). The treatment reduced the level of fluid filtration from the vascular channel to the interstitial space, but did not affect the level of reabsorption.
Murashov
A N
AN
Department of Fundamental Medicine, Moscow State University, Vorob'evy gory, Moscow, 119899 Russia.
Buriukov
R I
RI
Khokhlova
O N
ON
Medvedev
O S
OS
D000818:Animals; D001769:Blood / Q000187:drug effects; D001826:Body Fluids / Q000378:metabolism*; D002196:Capillaries / Q000378:metabolism; D003720:Densitometry; D004145:Diosmin / Q000494:pharmacology*; D006569:Hesperidin / Q000494:pharmacology*; D006614:Hindlimb / Q000098:blood supply*; D011187:Posture; D051381:Rats; D017208:Rats, Wistar
D004145:Diosmin; D006569:Hesperidin