title: Ground-based experiments complement microgravity flight opportunities in the investigation of the effects of space flight on the immune response:  is protein kinase C gravity sensitive?
abstract: This manuscript briefly reviews ground-based and flight experiments, discusses how those experiments complement each other, and details how those experiments lead us to speculate about the gravity-sensitive nature of protein kinase C.
authors.affiliation: Division of Biology, NSCORT, Kansas State University, Manhattan 66506, USA.
authors.forename: S K
authors.initials: SK
authors.lastname: Chapes
authors.forename: K M
authors.initials: KM
authors.lastname: Woods
authors.forename: J W
authors.initials: JW
authors.lastname: Armstrong
mesh_terms: D000818:Animals; D007111:Immunity, Cellular / Q000502:physiology*; D008214:Lymphocytes; D008264:Macrophages; D009504:Neutrophils; D011493:Protein Kinase C / Q000502:physiology*; D013026:Space Flight; D014409:Tumor Necrosis Factor-alpha; D014893:Weightlessness; D018474:Weightlessness Simulation
chemical_list: D014409:Tumor Necrosis Factor-alpha; D011493:Protein Kinase C