[Effects of wobenzyme on the blood proteinase-inhibitory system in elderly and senile patients with gastric and duodenal peptic ulcers].
The studies were made in 31 patient with gastric and duodenal peptic ulcer aged from 60 to 82 years. It has been ascertained that exacerbation of the condition is accompanied by decline in the lysis of azoalbumin (low-molecular proteins), by a decrease in the blood serum concentration of alpha 2-macroglobulin in the presence of an increased lysis of azocol (colagenolytic activity of the blood) and the blood serum content of aldehyde- and ketone derivatives. Administration of wobenzym and erbisol against the background of a differentiated basic therapy makes for improvement of the condition of the blood proteinase-inhibitory system, with the protein oxidative modification processes being on the decrease.
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D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D000418:Albumins / Q000378:metabolism; D000447:Aldehydes / Q000097:blood; D001391:Azo Compounds / Q000032:analysis; D001685:Biological Factors / Q000627:therapeutic use; D003094:Collagen / Q000032:analysis; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy*; D006801:Humans; D006867:Hydrolases / Q000627:therapeutic use*; D007659:Ketones / Q000097:blood; D008297:Male; D008875:Middle Aged; D010084:Oxidation-Reduction; D011480:Protease Inhibitors / Q000097:blood*; D012431:Rutin / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000188:drug therapy*; D000511:alpha-Macroglobulins / Q000032:analysis
D000276:Adjuvants, Immunologic; D000418:Albumins; D000447:Aldehydes; D001391:Azo Compounds; D001685:Biological Factors; D004338:Drug Combinations; D007659:Ketones; D011480:Protease Inhibitors; D000511:alpha-Macroglobulins; C031460:azoalbumin; C096287:erbisol; C028470:Azocoll; D012431:Rutin; C023295:Wobenzym; D003094:Collagen; D006867:Hydrolases