title: Anthelmintic activity of essential oil of Ocimum sanctum and eugenol.
abstract: The essential oil of Ocimum sanctum and eugenol, tested in vitro, showed potent anthelmintic activity in the Caenorhabditis elegans model. Eugenol exhibited an ED(50) of 62.1 microg/ml. Eugenol being the predominant component of the essential oil, is suggested as the putative anthelmintic principle.
authors.affiliation: Bioassay Unit, Research and Development Centre, Natural Remedies Pvt. Ltd., Plot No. 5B, Veerasandra Indl. Area, Hosur Road, Bangalore 561 229, India.
authors.forename: M K
authors.initials: MK
authors.lastname: Asha
authors.forename: D
authors.initials: D
authors.lastname: Prashanth
authors.forename: B
authors.initials: B
authors.lastname: Murali
authors.forename: R
authors.initials: R
authors.lastname: Padmaja
authors.forename: A
authors.initials: A
authors.lastname: Amit
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000494:pharmacology*; D017173:Caenorhabditis elegans / Q000187:drug effects*; D005054:Eugenol / Q000494:pharmacology*; D006801:Humans; D018649:Ocimum basilicum; D009822:Oils, Volatile / Q000494:pharmacology*; D021261:Parasitic Sensitivity Tests; D010938:Plant Oils / Q000494:pharmacology*
chemical_list: D000969:Antinematodal Agents; D009822:Oils, Volatile; D010938:Plant Oils; D005054:Eugenol