title: Combined transplantation of the heart, lung, and liver.
abstract: Combined transplantation of the heart, lung, and liver may be indicated in patients with either end-stage respiratory failure complicated by advanced liver disease or end-stage liver failure complicated by advanced lung disease. A retrospective review of nine patients who underwent combined heart-lung-liver transplantation in Cambridge (1986-99) was carried out. The 1-year and 5-year actuarial survival was 56% and 42%, respectively. Combined heart-lung-liver transplantation is a feasible option for a few patients and has a 5-year survival similar to heart-lung transplantation but with a lower incidence of acute and chronic rejection.
authors.forename: R K
authors.initials: RK
authors.lastname: Praseedom
authors.forename: K D
authors.initials: KD
authors.lastname: McNeil
authors.forename: C J
authors.initials: CJ
authors.lastname: Watson
authors.forename: G J
authors.initials: GJ
authors.lastname: Alexander
authors.forename: R Y
authors.initials: RY
authors.lastname: Calne
authors.forename: J
authors.initials: J
authors.lastname: Wallwork
authors.forename: P J
authors.initials: PJ
authors.lastname: Friend
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002423:Cause of Death; D002648:Child; D005260:Female; D006085:Graft Survival; D016027:Heart Transplantation; D006801:Humans; D016031:Liver Transplantation; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome