title: [Chagasic cardiopathy in Tehuantepec. Preliminary report].
abstract: American trypanosomosis was described in the state of Oaxaca, Mexico in 1936, and is probably endemic in rural areas. However, there is no information regarding chronic disease in the Isthmus of Tehuantepec, previous to this report.
  
  
  OBJECTIVE
  To identify the prevalence of American trypanosomosis and its consequences, such as the chronic chagas cardiomyopathy (CCC) among patients who were evaluated by the cardiology service in two general hospitals in Salina Cruz in the state of Oaxaca which is the main city of the Tehuantepec Region.
  
  
  METHODS
  Consecutive patients referred to the two cardiology services were identified as primary dilated myocardiopathy after a complete clinical and epidemiological history, chest roengentgram, EKG and echocardiogram. Blood was obtained through venipuncture and samples were studied for anti-Trypanosoma cruzi antibodies using validated indirect immunofluorescence, ELISA and Western blot assays.
  
  
  RESULTS
  Over a two period in which 540 cardiologic patients were examined, 16 (2.4% cases) of primary dilated cardiomyopathy were diagnosed and 13 (81%) of these were seropositive for anti-T. cruzi and therefore, fulfilled epidemiological and clinical criteria for chronic chagasic cardiomyopathy (CCC).
  
  
  CONCLUSIONS
  American trypanosomosis and CCC were diagnosed in cases of dilated cardiomyopathy within a geographical area where, there is an important distribution of triatomine bugs infected and Trypanosoma cruzi. Infection caused a progressive heart disease in this population exposed to insect vectors due to poor housing and sanitary conditions. The present study points out the need for further epidemiological studies in the Tehuantepec region.
authors.affiliation: Hospital General de PEMEX, México, D.F.
authors.forename: R M
authors.initials: RM
authors.lastname: Moreno López
authors.forename: L
authors.initials: L
authors.lastname: Sánchez Paredes
authors.forename: L
authors.initials: L
authors.lastname: Muñoz Jiménez
authors.forename: V M
authors.initials: VM
authors.lastname: Monteón
authors.forename: P A
authors.initials: PA
authors.lastname: Reyes López
mesh_terms: D000368:Aged; D002598:Chagas Cardiomyopathy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence