title: Structural and functional changes in man accompanying the weightlessness in "Skylab" flights: a mathematical approach.
abstract: The present paper reports a kinetic analysis of changes of some physiological parameters, obtained from international literature, after changes in gravitational environment. The overall phenomenology of the adaptation to weightlessness is characterized by a rapid process followed by a slow one. The two processes show half time values differing by about five times. Also in the case of readaptation to gravity, after recovery on the Earth, two well resolved processes, showing different half time values, are observed. It is of interest to notice that the rate of response to weightlessness is lower than that to gravity. Of course, the half time values observed depend on the different physiological parameters considered. In any case, the experimental data suggest a general trend of many adaptive changes, that may all be described by a simple mathematical model.
authors.affiliation: Institute of Chemistry, University of Rome, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Ascenzi
authors.forename: G
authors.initials: G
authors.lastname: Amiconi
authors.forename: A
authors.initials: A
authors.lastname: Scano
mesh_terms: D000222:Adaptation, Physiological; D000337:Aerospace Medicine; D015992:Body Mass Index; D002118:Calcium / Q000378:metabolism / Q000652:urine; D006801:Humans; D008954:Models, Biological; D013026:Space Flight; D013997:Time Factors; D014893:Weightlessness
chemical_list: D002118:Calcium