title: Immunomodulation of phytohormones and functional proteins in plant cells.
abstract: Recombinant antibodies expressed ectopically in plant cells recognize their corresponding antigens and can therefore bind specifically to phytohormones and proteins in vivo. The generation of antibody-antigen complexes interferes with the functions of the targets and affects the phenotype of transgenic plants. Recombinant antibodies can accumulate in different cell compartments and organs of transgenic plants at different stages of development. High levels of expression of specific, high-affinity antibodies are required for immunomodulation. Here, we discuss several models and examples of the antibody-mediated modulation of phytohormone and protein functions in terms of their potential for plant research.
authors.affiliation: Institut für Pflanzengenetik und Kulturpflanzenforschung Gatersleben, Corrensstrasse 3, D-06466 Gatersleben, Germany. conradu@ipk-gatersleben.de
authors.forename: U
authors.initials: U
authors.lastname: Conrad
authors.forename: R
authors.initials: R
authors.lastname: Manteuffel
mesh_terms: D000040:Abscisic Acid / Q000276:immunology* / Q000378:metabolism; D000906:Antibodies / Q000235:genetics / Q000276:immunology* / Q000494:pharmacology; D006360:Heat-Shock Proteins / Q000235:genetics / Q000276:immunology; D007135:Immunoglobulin Variable Region / Q000235:genetics / Q000276:immunology; D019684:Magnoliopsida / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D010937:Plant Growth Regulators / Q000276:immunology* / Q000378:metabolism; D030821:Plants, Genetically Modified; D011994:Recombinant Proteins; D015398:Signal Transduction
chemical_list: D000906:Antibodies; D006360:Heat-Shock Proteins; D007135:Immunoglobulin Variable Region; D010937:Plant Growth Regulators; D011994:Recombinant Proteins; D000040:Abscisic Acid