title: Carbon dioxide laser and silver halide infrared transmitting fibers for tympanoplasty: an experimental animal model.
abstract: OBJECTIVE
  This study evaluates the effectiveness and safety of fiberoptic carbon dioxide (CO2) laser welding for graft closure of tympanic membrane perforations in an animal model.
  
  
  METHODS
  Tympanic membrane perforation was surgically induced in 11 eardrums of 7 given pigs. A lumbar facial graft was placed over the wound, and albumin drops served as a biologic solder. CO2 laser energy, transmitted through silver halide infrared transmitting fibers, was used for "spot-welding" along the circumference of the graft. The welded sites were evaluated by using a surgical microscope as well as by evaluating the sites histologically.
  
  
  RESULTS
  Healing started 3 to 4 days after surgery and was completed within 3 weeks with the formation of a neotympanum. Some inflammation with granulation tissue was noted in 5 eardrums.
  
  
  CONCLUSIONS
  These preliminary results indicate that CO2 laser tympanoplasty with a fiberoptic delivery system may be a promising new technique for the clinical setting.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery and Laser Research, Rabin Medical Center, Petah Tiqva, Israel.
authors.forename: Z
authors.initials: Z
authors.lastname: Zilker
authors.forename: B I
authors.initials: BI
authors.lastname: Nageris
authors.forename: R
authors.initials: R
authors.lastname: Feinmesser
authors.forename: E
authors.initials: E
authors.lastname: Fridman
authors.forename: A
authors.initials: A
authors.lastname: Ravid
authors.forename: N
authors.initials: N
authors.lastname: Kariv
authors.forename: A
authors.initials: A
authors.lastname: Katzir
mesh_terms: D000818:Animals; D002245:Carbon Dioxide; D005240:Feasibility Studies; D005336:Fiber Optic Technology; D006168:Guinea Pigs; D053685:Laser Therapy / Q000379:methods; D023421:Models, Animal; D009225:Myringoplasty / Q000379:methods*; D018058:Tympanic Membrane Perforation / Q000601:surgery*; D014945:Wound Healing
chemical_list: D002245:Carbon Dioxide