title: Ubiquitylation in plants: a post-genomic look at a post-translational modification.
abstract: In this article, we summarize Arabidopsis genes encoding ubiquitin, ubiquitin-activating enzyme (E1), ubiquitin-conjugating enzymes (E2s) and an additional selected set of proteins related to ubiquitylation. We emphasize comparisons to components from Saccharomyces cerevisiae, with occasional reference to animals. Among the E1 and E2s, Arabidopsis usually has two to four probable orthologs to one yeast gene. Also, Arabidopsis has genes with no likely ortholog in yeast, although they often have potential orthologs in animals. The large number of components with known function in ubiquitylation indicates that this process plays a complex role in cellular physiology.
authors.affiliation: Institute of Botany, University of Vienna, Rennweg 14, A-1030 Vienna, Austria. bachmair@s1.botanik.unvie.ac.at
authors.forename: A
authors.initials: A
authors.lastname: Bachmair
authors.forename: M
authors.initials: M
authors.lastname: Novatchkova
authors.forename: T
authors.initials: T
authors.lastname: Potuschak
authors.forename: F
authors.initials: F
authors.lastname: Eisenhaber
mesh_terms: D017360:Arabidopsis / Q000145:classification / Q000235:genetics*; D005800:Genes, Fungal; D017343:Genes, Plant; D008025:Ligases / Q000145:classification / Q000235:genetics*; D011499:Protein Processing, Post-Translational; D012441:Saccharomyces cerevisiae / Q000145:classification / Q000235:genetics*; D025801:Ubiquitin / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D044764:Ubiquitin-Activating Enzymes; D044763:Ubiquitin-Conjugating Enzymes; D044767:Ubiquitin-Protein Ligases
chemical_list: D025801:Ubiquitin; D044763:Ubiquitin-Conjugating Enzymes; D044767:Ubiquitin-Protein Ligases; D008025:Ligases; D044764:Ubiquitin-Activating Enzymes