title: AKT plays a central role in tumorigenesis.
authors.affiliation: Human Genetics Program, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA. JR_Testa@fccc.edu
authors.forename: J R
authors.initials: JR
authors.lastname: Testa
authors.forename: A
authors.initials: A
authors.lastname: Bellacosa
mesh_terms: D000818:Animals; D017209:Apoptosis; D002471:Cell Transformation, Neoplastic; D006801:Humans; D010766:Phosphorylation; D017346:Protein Serine-Threonine Kinases; D011505:Protein-Tyrosine Kinases / Q000235:genetics / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000235:genetics* / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt; D014407:Tumor Cells, Cultured
chemical_list: D011518:Proto-Oncogene Proteins; D011505:Protein-Tyrosine Kinases; C494918:AKT1 protein, human; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt