Cervical cancer screening from Pap smear to human papillomavirus DNA testing.
Human papillomavirus (HPV) types 16 and 18 are strongly associated with cervical cancer. Testing of HPV DNA in cervical specimens offers an useful option in triaging women with equivocal Pap smear diagnosis such as atypical squamous cells of undetermined significance.
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Department of General Internal Medicine, S70, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195, USA.
Xu
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D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008403:Mass Screening; D065006:Papanicolaou Test; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000150:complications / Q000175:diagnosis*; D014218:Triage / Q000379:methods; D014481:United States; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000821:virology; D014626:Vaginal Smears
D004279:DNA, Viral