title: Does ovarian surgery for endometriomas impair the ovarian response to gonadotropin?
abstract: OBJECTIVE
  To evaluate the ovarian response to stimulation conducted for IVF treatment in women who have undergone conservative surgery for endometriomas.
  
  
  METHODS
  Retrospective study with prospective selection of participants and controls.
  
  
  METHODS
  University infertility clinic.
  
  
  METHODS
  A series of 374 women who underwent in vitro fertilization (IVF). The study group consisted of 85 patients with ovarian endometriomas who had undergone laparoscopic surgery in an attempt to become pregnant, but had failed within a year of surgery. The control group consisted of 289 patients with tubal factor infertility.
  
  
  METHODS
  IVF-embryo transfer procedures.
  
  
  METHODS
  Stimulation parameters, fertilization, implantation, and pregnancy rates were analyzed in both groups.
  
  
  RESULTS
  There was no significant difference between the two groups in stimulation parameters or IVF outcome.
  
  
  CONCLUSIONS
  A total of 820 cycles were analyzed. A similar IVF-ET outcome was observed in patients with endometriosis after ablation of endometriomas compared to women with tubal factors. In conclusion, endometrioma surgery by internal wall vaporization does not impair IVF outcome. The clinical pregnancy rate was respectively 37.4% and 34.6% in the endometriosis group and the control group.
authors.affiliation: Department of Gynecology, Université Catholique de Louvain, Cliniques Universitaires St. Luc, Brussels, Belgium. donnez@gyne.ucl.ac.be
authors.forename: J
authors.initials: J
authors.lastname: Donnez
authors.forename: C
authors.initials: C
authors.lastname: Wyns
authors.forename: M
authors.initials: M
authors.lastname: Nisolle
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D004715:Endometriosis / Q000150:complications / Q000601:surgery*; D005184:Fallopian Tube Diseases / Q000150:complications; D005260:Female; D005307:Fertilization in Vitro; D006062:Gonadotropins / Q000494:pharmacology*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D010535:Laparoscopy; D010049:Ovarian Diseases / Q000150:complications / Q000601:surgery*; D010053:Ovary / Q000187:drug effects* / Q000601:surgery*; D011247:Pregnancy; D018873:Pregnancy Rate; D012016:Reference Values; D012189:Retrospective Studies; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D006062:Gonadotropins