Pierre Robin sequence: a series of 117 consecutive cases.
A series of 117 cases of Pierre Robin Sequence are classified as isolated (48%), syndromic (35%), and with associated anomalies (17%); the latter group had a poor long-term prognosis. In isolated Pierre Robin Sequence, familial cases and a high incidence of twins were noted. Among syndromic Pierre Robin Sequence, 4 syndromes represent more than 50% of the diagnoses.
Holder-Espinasse
M
M
Department of Genetics, Necker Enfants-Malades Hospital, Paris, France.
Abadie
V
V
Cormier-Daire
V
V
Beyler
C
C
Manach
Y
Y
Munnich
A
A
Lyonnet
S
S
Couly
G
G
Amiel
J
J
D002675:Child, Preschool; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D010375:Pedigree; D010855:Pierre Robin Syndrome / Q000175:diagnosis* / Q000235:genetics* / Q000401:mortality; D011379:Prognosis; D015996:Survival Rate