Childhood methanol ingestion treated with fomepizole and hemodialysis.
Fomepizole (4-methylpyrazole; Antizol) is used increasingly in the treatment of methanol toxicity in adults. Little experience exists with this drug in the pediatric population, however. We present a case of methanol poisoning in a child in whom the use of fomepizole averted intravenous ethanol infusion and the attendant side effects of this therapy.
Brown
M J
MJ
Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Shannon
M W
MW
Woolf
A
A
Boyer
E W
EW
D000328:Adult; D000931:Antidotes / Q000627:therapeutic use*; D002675:Child, Preschool; D000077604:Fomepizole; D006801:Humans; D008297:Male; D000432:Methanol / Q000506:poisoning*; D011041:Poisoning / Q000188:drug therapy; D011720:Pyrazoles / Q000627:therapeutic use*; D006435:Renal Dialysis / Q000379:methods*
D000931:Antidotes; D011720:Pyrazoles; D000077604:Fomepizole; D000432:Methanol