title: Preliminary characteristics of the prothrombin converting enzyme from venom of Stephen's banded snake (Hoplocephalus stephensii).
abstract: Stephen's banded snake (Hoplocephalus stephensii) is an infrequently encountered Australian elapid species. The crude venom contains coagulant activity and the component responsible is a prothrombin activator requiring factor V for activity. SDS-PAGE of the isolated native protein revealed two bands at 23 and 36 kDa. These findings indicate that the procoagulant is similar to that found in the Australian tiger snake (Notechis scutatus) and thus resembles factor Xa.
authors.affiliation: Flinders University School of Medicine, Bedford Park, Australia.
authors.forename: S A
authors.initials: SA
authors.lastname: Weinstein
authors.forename: V
authors.initials: V
authors.lastname: Williams
authors.forename: J
authors.initials: J
authors.lastname: White
mesh_terms: D000818:Animals; D003029:Coagulants / Q000302:isolation & purification*; D020147:Coagulation Protein Disorders / Q000097:blood; D004546:Elapid Venoms / Q000737:chemistry* / Q000201:enzymology; D004591:Electrophoresis, Polyacrylamide Gel; D015951:Factor Xa / Q000302:isolation & purification*; D005260:Female; D008297:Male; D014914:Whole Blood Coagulation Time
chemical_list: D003029:Coagulants; D004546:Elapid Venoms; D015951:Factor Xa