title: [Effect of stearoylethanolamine on composition of various classes of lipids in rat heart tissue under ischemia-reperfusion].
abstract: The effect N-stearoilethanolamines on lipide classes and their fatty acid composition was studied in the isolated rat heart under ischemia--reperfusion. It was shown that the amount of cholesterol esters increased at ischemia--reperfusion by 4.6 fold. The addition of 10(-7) M, 10(-6) M and 10(-5) M of N-stearoilethanolamines into perfused solution prevented these negative consequences of the myocardium ischemic injury. The addition of N-stearoilethanolamines decreased the quantity oleinic (18:1 omega 9) and free n-6 fatty acids. N-stearoilethanolamine lowered the amount of short chain saturated fatty acids and also polyunsaturated n-6 fatty acids in cholesterol esters. As well the lipide composition of perfused solutions was also investigated.
authors.affiliation: Palladin Institute of Biochemistry, National Academy of Science of Ukraine, Kyiv.
authors.forename: M V
authors.initials: MV
authors.lastname: Artamonov
authors.forename: N M
authors.initials: NM
authors.lastname: Hula
authors.forename: V M
authors.initials: VM
authors.lastname: Klimashevs'kyĭ
authors.forename: O D
authors.initials: OD
authors.lastname: Zhukov
authors.forename: V M
authors.initials: VM
authors.lastname: Marhitych
authors.forename: V V
authors.initials: VV
authors.lastname: Frol'kys
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000737:chemistry*; D004983:Ethanolamines / Q000494:pharmacology*; D005227:Fatty Acids / Q000737:chemistry*; D005231:Fatty Acids, Unsaturated / Q000737:chemistry*; D066298:In Vitro Techniques; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D015427:Reperfusion Injury / Q000378:metabolism*; D013229:Stearic Acids / Q000494:pharmacology*
chemical_list: D004983:Ethanolamines; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; C408368:N-stearoylethanolamine; D013229:Stearic Acids; D002784:Cholesterol