title: [Ganglion block in cardiopulmonary bypass surgery].
abstract: Ganglion blockers increase the antinociceptive defense in anesthesiological support of cardiopulmonary bypass operations for mitral and aortic valve failure. Benzohexonium decreased total peripheral vascular resistance, increased cardiac and stroke indexes, and increased systolic potency of the heart. Ganglionar blocking was associated with an increase of systemic oxygen transport, arrhythmias developed rarely, blood concentrations of epinephrine, norepinephrine, ACTH, vasopressin, and leukinferon were lower.
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Gorokhovatskiĭ
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Polushin
authors.forename: G G
authors.initials: GG
authors.lastname: Khubulava
authors.forename: N N
authors.initials: NN
authors.lastname: Shikhverdiev
authors.forename: V A
authors.initials: VA
authors.lastname: Karlov
authors.forename: N A
authors.initials: NA
authors.lastname: Kulikova
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000601:surgery*; D002315:Cardiopulmonary Bypass; D004837:Epinephrine / Q000097:blood; D005260:Female; D005730:Ganglionic Blockers / Q000008:administration & dosage / Q000494:pharmacology*; D006439:Hemodynamics / Q000187:drug effects; D006584:Hexamethonium Compounds / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D009638:Norepinephrine / Q000097:blood; D010100:Oxygen / Q000378:metabolism; D013318:Stroke Volume / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects; D014667:Vasopressins / Q000097:blood
chemical_list: D005730:Ganglionic Blockers; D006584:Hexamethonium Compounds; D014667:Vasopressins; D000324:Adrenocorticotropic Hormone; D010100:Oxygen; C021628:benzohexonium; D009638:Norepinephrine; D004837:Epinephrine