title: Treatment of recurrent auricle pseudocyst with intralesional injection of minocycline: a report of two cases.
abstract: Pseudocyst of the auricle (PCA) is characterized by asymptomatic and fluctuant swelling of the external ear and frequent relapses despite various therapeutic approaches. We describe two patients with recurrent PCA who were successfully treated with intralesional injection of 1 mg/mL of minocycline hydrochloride (minocycline), 2 or 3 times at 2-week intervals. Intralesional injection of minocycline may be a new therapeutic choice for conservative management of PCA, especially in recurrent cases. The mechanisms of minocycline action that may have led to reduction of the cystic lesions are discussed.
authors.affiliation: Department of Dermatology, Fukushima Medical University School of Medicine, Fukushima, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Oyama
authors.forename: M
authors.initials: M
authors.lastname: Satoh
authors.forename: K
authors.initials: K
authors.lastname: Iwatsuki
authors.forename: F
authors.initials: F
authors.lastname: Kaneko
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002357:Cartilage Diseases / Q000188:drug therapy*; D004423:Ear / Q000473:pathology*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage* / Q000627:therapeutic use; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline