Melanoma-associated retinopathy and recurrent exudative retinal detachments in a patient with choroidal melanoma.
OBJECTIVE
To report a patient who presented with photopsias, night blindness, exudative retinal detachments, and melanoma-associated retinopathy in her right eye 23 years after the left eye was enucleated for a choroidal melanoma.


METHODS
Assessment of fundus findings, fluorescein angiograms, and electroretinograms.


RESULTS
The patient had recurrent exudative detachments of the macula in her right eye and electroretinogram responses consistent with the diagnosis of melanoma-associated retinopathy. The abdominal computed tomography (CT) scan was negative, but 13 months later, CT scanning revealed many masses in her liver. Fine-needle biopsy confirmed the diagnosis of metastatic melanoma.


CONCLUSIONS
To our knowledge, this is the first report of melanoma-associated retinopathy in a patient with a previous choroidal melanoma.
Zacks
D N
DN
Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA. David_Zacks@meei.harvard.edu
Pinnolis
M K
MK
Berson
E L
EL
Gragoudas
E S
ES
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002830:Choroid Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D004596:Electroretinography; D005122:Exudates and Transudates; D017809:Fatal Outcome; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000209:etiology; D008545:Melanoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012008:Recurrence; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014792:Visual Acuity
D000970:Antineoplastic Agents