title: Melanoma-associated retinopathy and recurrent exudative retinal detachments in a patient with choroidal melanoma.
abstract: OBJECTIVE
  To report a patient who presented with photopsias, night blindness, exudative retinal detachments, and melanoma-associated retinopathy in her right eye 23 years after the left eye was enucleated for a choroidal melanoma.
  
  
  METHODS
  Assessment of fundus findings, fluorescein angiograms, and electroretinograms.
  
  
  RESULTS
  The patient had recurrent exudative detachments of the macula in her right eye and electroretinogram responses consistent with the diagnosis of melanoma-associated retinopathy. The abdominal computed tomography (CT) scan was negative, but 13 months later, CT scanning revealed many masses in her liver. Fine-needle biopsy confirmed the diagnosis of metastatic melanoma.
  
  
  CONCLUSIONS
  To our knowledge, this is the first report of melanoma-associated retinopathy in a patient with a previous choroidal melanoma.
authors.affiliation: Retina Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA. David_Zacks@meei.harvard.edu
authors.forename: D N
authors.initials: DN
authors.lastname: Zacks
authors.forename: M K
authors.initials: MK
authors.lastname: Pinnolis
authors.forename: E L
authors.initials: EL
authors.lastname: Berson
authors.forename: E S
authors.initials: ES
authors.lastname: Gragoudas
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002830:Choroid Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D004596:Electroretinography; D005122:Exudates and Transudates; D017809:Fatal Outcome; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000209:etiology; D008545:Melanoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012008:Recurrence; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014792:Visual Acuity
chemical_list: D000970:Antineoplastic Agents