title: Synthesis and stereochemical characterization of diastereomeric nucleoside-phosphorothioselenoates by NMR methods.
abstract: Synthesis and stereochemical characterization of enantiomerically pure nucleoside-phosphorothioselenoates are reported. The effects of solvent and temperature on the vicinal carbon-phosphorus couplings are described and the results are interpreted in terms of conformational changes influenced by stacking interactions between the bases and the phenyl rings.
authors.affiliation: Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Budapest.
authors.forename: M
authors.initials: M
authors.lastname: Kajtár-Peredy
authors.forename: I
authors.initials: I
authors.lastname: Tömösközi
authors.forename: E
authors.initials: E
authors.lastname: Gács-Baitz
mesh_terms: D057927:Hydrophobic and Hydrophilic Interactions; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D018036:Selenium Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D012997:Solvents; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D009705:Nucleosides; D018036:Selenium Compounds; D012997:Solvents