[Preliminary studies on chemical constituents and pharmacological action of Eclipta prostrata L].
OBJECTIVE
To study the pharmacologically active components of Eclipta prostrata.


METHODS
The components were extracted by alcohol and isolated by silica gel column and subjected to pharmacological screening.


RESULTS
Four compounds were isolated from E. prostrata, of which two were identified as stigmasterol and alpha-terthienyl.


CONCLUSIONS
alpha-Terthienyl was isolated from the plant for the first time. The EtOAc part of alcoholic extraction exhibits significant hepatoprotective activity against carbon terachloride-induced liver injury in rats.
Han
Y
Y
Jiangsu Provincial Institute of Materia Medica, Nanjing 210009.
Xia
C
C
Cheng
X
X
Xiang
R
R
Liu
H
H
Yan
Q
Q
Xu
D
D
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D019659:Asteraceae / Q000737:chemistry*; D002252:Carbon Tetrachloride Poisoning; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology* / Q000209:etiology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology*; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry*; D011897:Random Allocation; D013265:Stigmasterol / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D004365:Drugs, Chinese Herbal; D013265:Stigmasterol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase