The balance of power in RNA trafficking.
In the past two years, several different RNA trafficking pathways have been characterized in oligodendrocytes; similar trafficking pathways have been discovered in neuronal and retroviral systems; co-assembly of multiple different RNAs into the same granules has been analyzed as a mechanism for coordinating gene expression; and a new hypothesis for RNA trafficking, based on the balance of power between kinesin and dynein in individual RNA granules, has been proposed.
Carson
J H
JH
Department of Biochemistry, University of Connecticut Health Center, Farmington, CT 06030, USA. jcarson@nso2.uchc.edu
Cui
H
H
Barbarese
E
E
D000818:Animals; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D006801:Humans; D009836:Oligodendroglia / Q000502:physiology; D021381:Protein Transport / Q000235:genetics* / Q000502:physiology; D012313:RNA / Q000502:physiology*; D012261:Ribonucleoproteins / Q000235:genetics / Q000502:physiology
D034441:Heterogeneous-Nuclear Ribonucleoproteins; D012261:Ribonucleoproteins; D012313:RNA