title: [Anesthetic blockade of the greater occipital nerve in migraine prophylaxis].
abstract: Migraine comprises a great many encephalic structures in its pathophysiology with the trigeminal nerve (TN) type being one of the main ones. For the purpose of determining a possible influence of the greater occipital nerve (GON) on migraine behavior, 37 patients who showed this pathology were studied. Using a double blind "cross over" group and submitting those patients to a GON infiltration with bupivacaina 0.5% (BP) and physiological serum 0.9% (PS), the clinical effects were evaluated: subjectively, through a pain analytical visual scale; objectively, by determining the threshold of pain perception (algometry). The comparison between the two groups (BP-PS) and (PS-BP) has shown that the number and duration of the attacks did not show significant statistical differences during the study. The intensity of the attacks was lower in group (BP-PS) only after the second infiltration (p=0.020), in the other moments no differences have been observed between the groups. The conclusion is that the anesthetic blockage with BP on the GON does not change the number of crises and their duration, but it does provokes an intensity reduction after 60 days from the infiltration. The results shown here suggest that GON participates in the cranial nociceptive modulation during crises of migraine without aura.
authors.affiliation: Unidade de Cefaléias, Especialidade e Serviço de Neurologia, Departamento de Clínica Médica, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brasil. piovesan@avalon.sul.com.br
authors.forename: E J
authors.initials: EJ
authors.lastname: Piovesan
authors.forename: L C
authors.initials: LC
authors.lastname: Werneck
authors.forename: P A
authors.initials: PA
authors.lastname: Kowacs
authors.forename: C E
authors.initials: CE
authors.lastname: Tatsui
authors.forename: M C
authors.initials: MC
authors.lastname: Lange
authors.forename: M
authors.initials: M
authors.lastname: Vincent
mesh_terms: D000293:Adolescent; D000328:Adult; D000779:Anesthetics, Local; D002045:Bupivacaine; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D020326:Migraine without Aura / Q000503:physiopathology / Q000517:prevention & control*; D009333:Neck / Q000294:innervation; D009407:Nerve Block; D010147:Pain Measurement; D013126:Spinal Nerve Roots; D013997:Time Factors
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine