Helicobacter pylori and nonsteroidal anti-inflammatory drugs: synergy or null effect?
Both Helicobacter pylori infection and nonselective, nonsteroidal anti-inflammatory drugs (NSAIDs) contribute to a greater risk of gastric and duodenal ulcers, ulcer complications, and gastrointestinal bleeding. Prospective investigations are needed to learn what is the net effect of the combination of H pylori and NSAIDs.
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D004381:Duodenal Ulcer / Q000139:chemically induced / Q000209:etiology; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced / Q000209:etiology; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D017063:Outcome Assessment, Health Care; D013276:Stomach Ulcer / Q000139:chemically induced / Q000209:etiology; D014481:United States
D000894:Anti-Inflammatory Agents, Non-Steroidal