title: Localized laryngotracheobronchial amyloidosis: case report and review of the literature.
abstract: Although localized laryngotracheobronchial amyloidosis is rare, the otolaryngologist--head and neck surgeon should be familiar with this condition. Its characteristic appearance can suggest its presence in a patient who has the typical initial symptoms. Biopsies during direct laryngoscopy and bronchoscopy can play both a diagnostic and therapeutic role. After an appropriate examination to rule out systemic involvement, the patient should be managed with conservative surgery, although the use of a CO2 laser might be more efficacious than conventional surgery. With appropriate diagnosis and treatment, patients should expect a favorable prognosis. In this article, we describe a new case of localized laryngotracheobronchial amyloidosis in a 67-year-old woman, and we review the literature on this subject.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, P.O. Box 250582, 150 Ashley Ave., Charleston, SC 29425, USA. clarkm@musc.edu
authors.forename: J M
authors.initials: JM
authors.lastname: Clark
authors.forename: M C
authors.initials: MC
authors.lastname: Weissler
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis / Q000601:surgery*; D012720:Severity of Illness Index; D014133:Tracheal Diseases / Q000175:diagnosis / Q000601:surgery*