title: [Optimization of surgical treatment of suppurative-necrotic lesions of the foot in patients with diabetes mellitus].
abstract: The analysis of treatment results in 559 patients with diabetes mellitus complicated by foot pyonecrotic lesions was carried out. Surgical treatment was performed in 448 patients considering route of infection spread (basic group), conventional methods of treatment were used in 111 patients (control group). It is shown that one of the causes of unsuccessful treatment results was the infection spread from foot to leg by toes tendons and synovial sheaths. The study of microbial contamination in wound exudate, distal and proximal sites of tendons revealed a significant difference in proximal-distal gradient for aerobes (2.8 +/- 0.19 lg/g) and anaerobes (1.71 +/- 0.16 lg/g, p < 0.01). Methods of surgical treatment of foot pyonecrotic lesions allowing for route of infection in patients with diabetes mellitus were developed. Use of these methods allowed to decrease more than 2 times the number of femoral amputations, and to increase the rate of surgical interventions with salvage of limb's support function from 71.2 to 87.7%.
authors.forename: Sh I
authors.initials: ShI
authors.lastname: Karimov
authors.forename: B D
authors.initials: BD
authors.lastname: Babadzhanov
authors.forename: M S
authors.initials: MS
authors.lastname: Islamov
authors.forename: B B
authors.initials: BB
authors.lastname: Zhanibaev
authors.forename: A R
authors.initials: AR
authors.lastname: Babebekov
mesh_terms: D000671:Amputation, Surgical; D001419:Bacteria / Q000302:isolation & purification; D017719:Diabetic Foot / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D006801:Humans; D009336:Necrosis; D013492:Suppuration; D013997:Time Factors