N-3 fatty acids and cardiac function after myocardial infarction in Denmark.
In order to evaluate the effect of marine n-3 polyunsaturated fatty acids (n-3 PUFA) on systolic left ventricular function, we investigated the effect of daily supplementation with 5.2 g n-3 PUFA for 12 weeks in 55 patients with a recent myocardial infarction in a double blind placebo-controlled design. Left ventricular function was assessed by transthoracal echo-cardiography and plasma concentration of proANP and N-terminal proANP. No effect of n-3 PUFA could be demonstrated on these indices of left ventricular function.
Skou
H A
HA
Department of Medicine, Hjørring Hospital, Denmark. helleskou@hotmail.com
Toft
E
E
Christensen
J H
JH
Hansen
J B
JB
Dyerberg
J
J
Schmidt
E B
EB
D000368:Aged; D019587:Dietary Supplements; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D004452:Echocardiography; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D011336:Probability; D012016:Reference Values; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology
D015525:Fatty Acids, Omega-3