[Spontaneous mutagenesis in different strains of mice during aging].
The article is devoted the problem of mutagenesis during aging. There is identical affirmative dynamics of chromosome aberration frequencies in male of transgenic and control non-transgenic mice of age. Spontaneous chromosome aberration frequencies in somatic cells in young age differ in transgenic and control mice more, than in older mice.
Rozenfel'd
S V
SV
Department of Medical Biology and Genetics, I.P. Pavlov St. Petersburg State Medical University, 197089, St. Petersburg, Lva Tolstogo Str., 6/8. biology@spmu.rssi.ru
D000375:Aging / Q000502:physiology*; D000818:Animals; D002274:Carcinogens, Environmental / Q000009:adverse effects*; D002869:Chromosome Aberrations; D004781:Environmental Exposure / Q000009:adverse effects; D006579:Heterozygote; D006720:Homozygote; D051379:Mice; D008810:Mice, Inbred C57BL; D016296:Mutagenesis / Q000502:physiology*; D009857:Oncogenes / Q000235:genetics; D011110:Polymorphism, Genetic
D002274:Carcinogens, Environmental