title: [Destructed knee in patient with systemic lupus erythematosus treated with total knee arthroplasty: a case report].
abstract: We reported a case of a 61-year-old female with arthritis of right knee associated with systemic lupus erythematosus (SLE). She suffered from SLE at age 31 and felt pain around her right knee at age 60. It gradually increased despite intraarticular injections of steroid and arthroscopic synovectomy. On admission, the range of motion of her right knee was 20 to 135 degrees and remarkable gait disturbance were noted due to the pain. Radiographs of the right knee showed joint space narrowing and bone erosion. YMCK total knee arthroplasty was performed. Operation findings showed smooth and thick synovium and cartilage defect. Histological examination revealed fibrin on surface, proliferad connective tissue and newly development of vasculature. Synovium eroded both cartilage and bone. In SLE, soft tissue contructure was reported to be a main cause of joint dislocation, but there were only a few report of progressive joint destruction due to SLE. In this case, the main cause of joint destruction may be invasion synovium into cartilage and bone.
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University, Fukuura, Kanagawa-ku, Yokohama-city.
authors.forename: M
authors.initials: M
authors.lastname: Yanase
authors.forename: T
authors.initials: T
authors.lastname: Koshino
authors.forename: S
authors.initials: S
authors.lastname: Mitsuhashi
authors.forename: R
authors.initials: R
authors.lastname: Takeuchi
authors.forename: K
authors.initials: K
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Saitoh
mesh_terms: D001168:Arthritis / Q000150:complications / Q000601:surgery*; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged