title: [Ultra-fast opiate detoxification under general anesthesia: preliminary results of the Liege protocol].
abstract: Many studies support the hypothesis of a substantial benefit in inducing an Opiate Receptor Blockade through a Rapid Opiate Detoxification under general Anaesthesia (RODA) in opiate dependent patients. However, prospective studies and long term evaluation of the technique are lacking. In order to evaluate long-term abstinence rates after a RODA among a sample of opiate addicts, a study was started in March 1999 at the University of Liège. To date, 45 patients were evaluated (mean age: 29 +/- 5 years) with a mean opiate dependence duration of 8 +/- 4 years. Most of them were both heroin and methadone dependent; 42.2% of them were included while 31.1% did not complete the whole inclusion procedure and 26.7% were excluded. None experienced severe withdrawal symptoms. At six months, abstinence rate was 67% and 46% at one year. These preliminary results suggest the interest of the procedure in carefully selected patients.
authors.affiliation: Service de Psychiatrie et de Psychologie médicale, Université de Liège.
authors.forename: E
authors.initials: E
authors.lastname: Pinto
authors.forename: J
authors.initials: J
authors.lastname: Reggers
authors.forename: M
authors.initials: M
authors.lastname: Delhez
authors.forename: S
authors.initials: S
authors.lastname: Fuchs
authors.forename: I
authors.initials: I
authors.lastname: Venneman
authors.forename: M
authors.initials: M
authors.lastname: Lamy
authors.forename: M
authors.initials: M
authors.lastname: Ansseau
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D001530:Belgium; D002985:Clinical Protocols; D005260:Female; D006801:Humans; D008297:Male; D009293:Opioid-Related Disorders / Q000628:therapy*; D013997:Time Factors