Synthesis and antibacterial activity of pyridyl thioureas and arylthiosemicarbazones.
[N-(2-pyridyl)-N'-(4-(un) substituted] thioureas and (substitutedaryl)thiosemicarbazones were synthesised and evaluated for their antibacterial activity. All aryl thiosemicarbazones showed good activity against Aeromonas hydrophilia and Salmonella typhimurium. But none of the pyridyl thioureas showed any prominent activity against tested bacteria.
Kumar
K S
KS
Department of Pharmaceutics, Institute of Technology, Banaras Hindu University, Varanasi, India.
Singh
S K
SK
Pandeya
S N
SN
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005658:Fungi / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000494:pharmacology*; D013890:Thiourea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D013882:Thiosemicarbazones; D013890:Thiourea