title: The nuclear pore complex.
abstract: Nuclear pore complexes, the conduits for information exchange between the nucleus and cytoplasm, appear broadly similar in eukaryotes from yeast to human. Precisely how nuclear pore complexes regulate macromolecular and ionic traffic remains unknown, but recent advances in the identification and characterization of components of the complex by proteomics and genomics have provided new insights.
authors.affiliation: Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA. s-adam@northwestern.edu
authors.forename: S A
authors.initials: SA
authors.lastname: Adam
mesh_terms: D000818:Animals; D023281:Genomics; D006801:Humans; D022022:Nuclear Pore / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D028861:Nuclear Pore Complex Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D020543:Proteome / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism
chemical_list: D028861:Nuclear Pore Complex Proteins; D020543:Proteome