title: The HMMTOP transmembrane topology prediction server.
abstract: The HMMTOP transmembrane topology prediction server predicts both the localization of helical transmembrane segments and the topology of transmembrane proteins. Recently, several improvements have been introduced to the original method. Now, the user is allowed to submit additional information about segment localization to enhance the prediction power. This option improves the prediction accuracy as well as helps the interpretation of experimental results, i.e. in epitope insertion experiments.
  
  
  BACKGROUND
  HMMTOP 2.0 is freely available to non-commercial users at http://www.enzim.hu/hmmtop. Source code is also available upon request to academic users.
authors.affiliation: Institute of Enzymology, BRC, Hungarian Academy of Sciences, H-1518 Budapest, PO Box 7, Hungary. tusi@enzim.hu
authors.forename: G E
authors.initials: GE
authors.lastname: Tusnády
authors.forename: I
authors.initials: I
authors.lastname: Simon
mesh_terms: D000465:Algorithms; D003198:Computer Simulation / Q000706:statistics & numerical data; D003628:Database Management Systems / Q000639:trends; D030562:Databases, Protein / Q000706:statistics & numerical data; D006801:Humans; D008390:Markov Chains; D008565:Membrane Proteins / Q000737:chemistry*; D015233:Models, Statistical; D017433:Protein Structure, Secondary; D012984:Software / Q000639:trends
chemical_list: D008565:Membrane Proteins