title: Bromo-boronolactonization of olefins.
abstract: Exposure of a variety of mono- and disubstituted ortho-alkenylarylboronic acids to NBS in THF/H(2)O under neutral conditions affords bromo-boronolactones, in some instances, with exceptional regiocontrol. The adducts, analogous to those formed by carboxylic acids, are shown to be useful synthetic intermediates.
authors.affiliation: Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9038, USA. j.flack@utsouthwestern.edu
authors.forename: J R
authors.initials: JR
authors.lastname: Falck
authors.forename: M
authors.initials: M
authors.lastname: Bondlela
authors.forename: S K
authors.initials: SK
authors.lastname: Venkataraman
authors.forename: D
authors.initials: D
authors.lastname: Srinivas
mesh_terms: D000475:Alkenes / Q000737:chemistry; D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis*
chemical_list: D000475:Alkenes; D001896:Boron Compounds; D001897:Boronic Acids; D007783:Lactones