Persistent migrainous visual phenomena might be responsive to lamotrigine.
Two patients with migraine reported having experienced persistent auralike visual phenomena for months to years. All laboratory investigations were normal except for occipital hypoperfusion on the brain single photon emission computed tomography. After lamotrigine treatment for 2 weeks, they both had a resolution of the visual symptoms. Persistent migrainous visual phenomena are potentially benign and probably a status of spontaneous aura.
Chen
W T
WT
Neurological Institute, Taipei Veterans General Hospital and the Department of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan.
Fuh
J L
JL
Lu
S R
SR
Wang
S J
SJ
D000328:Adult; D005260:Female; D006801:Humans; D000077213:Lamotrigine; D008875:Middle Aged; D020325:Migraine with Aura / Q000000981:diagnostic imaging / Q000188:drug therapy*; D009778:Occipital Lobe / Q000098:blood supply / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals; D012039:Regional Blood Flow; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014227:Triazines / Q000627:therapeutic use*
D019275:Radiopharmaceuticals; D014227:Triazines; D019690:Technetium Tc 99m Exametazime; D000077213:Lamotrigine