Rasmussen's syndrome associated with chronic brain stem encephalitis.
We report a 3-year-old boy with a clinical picture of Rasmussen's encephalitis who had clinical, radiological and pathological evidence of brain stem involvement resulting in death. In addition, there were unexpected neuropathological findings of severe bilateral mesial temporal sclerosis. We discuss the novel finding of brain stem involvement in this condition and the association with mesial temporal sclerosis.
McDonald
D
D
Department of Neurology, Our Lady's Hospital For Sick Children and Royal College of Surgeons in Ireland Medical School, Dublin.
Farrell
McMenamin
J
J
D001921:Brain / Q000473:pathology; D001933:Brain Stem / Q000473:pathology; D002644:Chickenpox / Q000175:diagnosis / Q000473:pathology; D002675:Child, Preschool; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000473:pathology; D004660:Encephalitis / Q000175:diagnosis* / Q000473:pathology; D018792:Encephalitis, Viral / Q000175:diagnosis / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D013702:Temporal Lobe / Q000473:pathology