[Estimation of LC50 of chemicals to rainbow trout by fragment constant method].
A fragment constant model for prediction of 96 h LC50 of chemicals to rainbow trout was developed based on measured experimental data of 258 chemicals collected from the literature. The accuracy and the robustness of the model were discussed. The coefficient of determination of the model is 0.9495 and the mean residual is 0.42 log-unit. The model is robust for both individual chemical or chemical class.
Xi
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X
Dept of Urban and Environ Sci., Peking University, MOE Lab. of Earth Surface Processes, Beijing 100871, China.
Xu
F
F
Cao
J
J
Tao
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S
D000818:Animals; D007928:Lethal Dose 50; D017686:Oncorhynchus mykiss; D021281:Quantitative Structure-Activity Relationship; D012044:Regression Analysis