Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: diagnosis and treatment.
Prompt recognition of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) and initiation of plasma exchange treatment is critical as it substantially decreases mortality. Nevertheless, death and long-term complications remain common. The recent relaxation of diagnostic criteria has dramatically increased the number of patients treated for clinically suspected TTP-HUS.
George
J N
JN
Department of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City 73190, USA. Jim-George@OUHSC.edu
Vesely
S K
SK
D000465:Algorithms; D005260:Female; D017359:HELLP Syndrome / Q000175:diagnosis; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D010951:Plasma Exchange; D011225:Pre-Eclampsia / Q000175:diagnosis; D011247:Pregnancy; D011696:Purpura, Thrombocytopenic / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D013577:Syndrome