On the validity of the two-cells model in the analysis of passive electrical properties of gap-junction connected cells.
It is a rather extended practice to derive electrophysiological data (membrane and contact conductances) from experimental data for gap-junction tissues assuming that electrical connections are reduced to cell pairs. It is here shown that, if the length constant is sufficiently large, the mentioned procedure can lead to qualitatively incorrect results.
Andreu
E
E
Instituto de Bioingenieria, Universidad Miguel Hernández, Alicante, Spain.
Fernandez
E
E
Louis
E
E
Ortega
G
G
Sanchez-Andres
J V
JV
D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D002477:Cells / Q000166:cytology*; D003198:Computer Simulation; D004553:Electric Conductivity; D004594:Electrophysiology; D008962:Models, Theoretical; D012160:Retina / Q000166:cytology; D014426:Turtles