Bleeding in a patient receiving platelet aggregation inhibitors.
We describe a patient who experienced intraoperative bleeding after being treated with platelet receptor glycoprotein IIb/IIIa antagonist eptifibatide. We used Sonoclot and Thrombelastograph to monitor antiplatelet effects of eptifibatide.
Waters
J H
JH
Department of General Anesthesiology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. Watersj@ccf.org
Anthony
D G
DG
Gottlieb
A
A
Sprung
J
J
D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery; D000077542:Eptifibatide; D005260:Female; D006470:Hemorrhage / Q000097:blood* / Q000139:chemically induced; D006801:Humans; D010455:Peptides / Q000009:adverse effects*; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D010979:Platelet Function Tests; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D013916:Thrombelastography
D010455:Peptides; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D000077542:Eptifibatide