title: Comparison of accuracy and safety of computed tomography guided and unguided transthoracic fine needle aspiration biopsy in diagnosis of lung lesions.
abstract: OBJECTIVE
  To study the accuracy and safety of CT guided and unguided transthoracic fine needle aspiration biopsy in diagnosis of lung lesions.
  
  
  METHODS
  The study was carried out in 79 hospitalised patients during the period 1997-1999. In 52 patients having peripheral and large sized lung lesion (> 5 cm in diameter) in chest X-ray unguided FNAB was performed and in the rest 27 patients having relatively central and small sized lesion (< 5 cm). CT guided FNAB was performed. Also in 15 patients having two times failed unguided aspiration, CT guided FNAB was performed.
  
  
  RESULTS
  The diagnostic yield of unguided aspiration was 71.1% (37 out of 52). Out of 37 patients 29 (78.3%) had malignant lesion and eight (21.6%) non-malignant lesion. Sensitivity and specificity for detecting malignancy was 90.6% and 100% respectively. Complications were seen in 10 patients (19.3%). Diagnostic yield of CT guided FNAB was 95.2% (40 out of 42), 33 (82.5 %) had malignant lesion, seven (17.5%) had benign lesion. Sensitivity and specificity for detecting malignancy was 97.1% and 100% respectively. Minor complications were seen in three patients (7.1%).
  
  
  CONCLUSIONS
  It was concluded that CT guided
authors.affiliation: Department of TB and Chest Diseases, SCB Medical College, Cuttack.
authors.forename: B K
authors.initials: BK
authors.lastname: Dash
authors.forename: S K
authors.initials: SK
authors.lastname: Tripathy
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008171:Lung Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D015641:Radiography, Interventional / Q000009:adverse effects / Q000592:standards*; D014057:Tomography, X-Ray Computed / Q000009:adverse effects / Q000592:standards*