title: Comparative performance of herpes simplex virus type 2-specific serologic assays from Meridian Diagnostics and MRL diagnostics.
abstract: MRL Diagnostics and Meridian Diagnostics have recently designed herpes simplex virus type 2 (HSV-2)-specific enzyme immunoassays for HSV-2 antibody detection. Blood donor sera were assayed for HSV-2 antibodies by both methods. The sensitivity, specificity, and efficiency were 97.9, 95.4, and 95.9% for the MRL assay and 83.2, 98.2, and 95.5% for the Meridian assay, respectively.
authors.affiliation: Department of Clinical Laboratory Sciences, University of Kentucky, Lexington, Kentucky 40536-0298, USA. jaribes@uky.edu
authors.forename: J A
authors.initials: JA
authors.lastname: Ribes
authors.forename: M
authors.initials: M
authors.lastname: Hayes
authors.forename: A
authors.initials: A
authors.lastname: Smith
authors.forename: J L
authors.initials: JL
authors.lastname: Winters
authors.forename: D J
authors.initials: DJ
authors.lastname: Baker
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D006558:Herpes Genitalis / Q000175:diagnosis* / Q000821:virology; D018258:Herpesvirus 2, Human / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
chemical_list: D000914:Antibodies, Viral; D011933:Reagent Kits, Diagnostic