title: Intracavitary therapy of noninvasive transitional cell carcinomas of the upper urinary tract. A review of the literature.
abstract: Noninvasive (stages Ta, T1, Tis) transitional cell carcinomas of the upper urinary tract are suitable for a conservative therapeutic approach. Intracavitary therapy (alone or as adjuvant treatment) has recently been proposed and successfully used by some authors. Even though bacillus Calmette-Guérin is the most frequent agent employed, chemotherapeutic drugs, such as mitomycin C and thiotepa, have also been successfully used. The current information available in the literature is therefore reviewed. According to the data available, intracavitary therapy is a worthwhile conservative therapeutic option for noninvasive upper urinary tract urotheliomas with acceptable side effects. For this reason it may be included in the routine urological armamentarium.
authors.affiliation: Department of Urology, University of Padua Medical School, Via Giustiniani, 2, I-35128 Padua, Italy. bassipf@unipd.it
authors.forename: P
authors.initials: P
authors.lastname: Bassi
authors.forename: M
authors.initials: M
authors.lastname: Iafrate
authors.forename: F
authors.initials: F
authors.lastname: Longo
authors.forename: A
authors.initials: A
authors.lastname: Iannello
authors.forename: G
authors.initials: G
authors.lastname: Mostaccio
authors.forename: A
authors.initials: A
authors.lastname: Ingrassia
authors.forename: M
authors.initials: M
authors.lastname: Repele
authors.forename: I M
authors.initials: IM
authors.lastname: Tavolini
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D001500:BCG Vaccine / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000628:therapy*; D006801:Humans; D007680:Kidney Neoplasms / Q000628:therapy*; D014516:Ureteral Neoplasms / Q000628:therapy*; D001749:Urinary Bladder Neoplasms / Q000628:therapy*
chemical_list: D000276:Adjuvants, Immunologic; D001500:BCG Vaccine