title: [Tumor necrosis factor alpha and interleukin 1-beta in serum of patients with tick-borne encephalitis].
abstract: The purpose of this work was to evaluate the changes of IL-1 beta and TNF-alpha serum concentrations among patients with TBE (tick-borne encephalitis) of mild and severe clinical course. The detection of cytokines was performed by immunometric assay twice before and after treatment. There was no significant changes in IL-1 beta serum concentration after treatment in both groups of patients. But concentration of TNF-alpha decreased significantly after treatment in both groups of patients. It seems that changes of TNF-alpha concentration might be helpful in evaluation of efficacy of aseptic central nervous system treatment.
authors.affiliation: Klinika Chorób Zakaznych i Neuroinfekcji AM w Białymstoku.
authors.forename: M
authors.initials: M
authors.lastname: Kondrusik
authors.forename: S
authors.initials: S
authors.lastname: Pancewicz
authors.forename: J
authors.initials: J
authors.lastname: Zajkowska
authors.forename: T
authors.initials: T
authors.lastname: Hermanowska-Szpakowicz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004675:Encephalitis, Tick-Borne / Q000097:blood*; D005260:Female; D006801:Humans; D007375:Interleukin-1 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha