[Dobutrex stress echocardiography: clinical and prognostic value, side effects].
OBJECTIVE
To study informative value of dobutrex echocardiography (DEC) in diagnosis of myocardial ischemia and viability, in prognostication of angina pectoris and myocardial infarction (MI), evaluation of DEC side effects.


METHODS
DEC was conducted in 74 patients with unconfirmed diagnosis (they had ischemic heart disease risk factors, atypical cardialgia) and 32 ischemic heart disease patients.


RESULTS
DEC proved to be an effective diagnostic tool in diagnosis of myocardial ischemia in patients with new-onset atypical cardialgia (informative value 73.6%). This test gives prognosis of the disease and improves treatment policy in patients with angina of effort and MI. The most serious and frequent side effects of DEC arising at the highest dobutrex dose were paroxysmal tachycardias (3.76%) and ventricular arrhythmias (6.58%). In most cases (99.1%) they discontinued after the test and did not require antiarrhythmic treatment. Thus, the test is relatively safe.


CONCLUSIONS
Echocardiography with dobutrex load should be used in practical cardiology more intensively.
Medvedeva
V N
VN
Orlova
O I
OI
Shashkov
E L
EL
Medvedev
V N
VN
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D002316:Cardiotonic Agents / Q000009:adverse effects; D004280:Dobutamine / Q000009:adverse effects; D025401:Echocardiography, Stress / Q000009:adverse effects; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*; D011379:Prognosis
D002316:Cardiotonic Agents; D004280:Dobutamine