title: Implantable cardioverter-defibrillator endocarditis secondary to Candida albicans.
abstract: The implantable cardioverter-defibrillator (ICD) represents an important advance in the treatment of ventricular arrhythmias, but infection has remained a serious complication of device implantation. Fungal infections associated with these devices are uncommon, with only 4 cases previously reported. We describe a case of ICD-associated endocarditis caused by Candida albicans that was successfully treated with complete device explantation and prolonged antifungal therapy, and we review the features of ICD-related fungal infections.
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, 35294-0006, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Brown
authors.forename: J W
authors.initials: JW
authors.lastname: Baddley
authors.forename: J E
authors.initials: JE
authors.lastname: Sanchez
authors.forename: L H
authors.initials: LH
authors.lastname: Bachmann
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D017147:Defibrillators, Implantable / Q000009:adverse effects*; D004696:Endocarditis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000209:etiology*; D017180:Tachycardia, Ventricular / Q000628:therapy
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B