title: Intermolecular Pauson-Khand reactions of cyclopropene: a general synthesis of cyclopentanones.
abstract: [reaction: see text] The Pauson-Khand reaction of cyclopropene with a variety of terminal alkynes has been studied. The best reaction conditions involve NMO activation in CH(2)Cl(2) at -35 degrees C. In this way, 3-substituted-bicyclo[3.1.0]hex-3-en-2-ones have been obtained in good to excellent yields. As a synthetic application, several types of substituted cyclopentenones have been prepared from these cycloadducts by protocols involving conjugate addition and reductive ring opening.
authors.affiliation: Departament de Química Orgànica, Martí i Franquès, 1-11, Barcelona E-08028, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Marchueta
authors.forename: X
authors.initials: X
authors.lastname: Verdaguer
authors.forename: A
authors.initials: A
authors.lastname: Moyano
authors.forename: M A
authors.initials: MA
authors.lastname: Pericàs
authors.forename: A
authors.initials: A
authors.lastname: Riera