[The phospholipid spectrum of platelet membranes in patients with COPD in the abating exacerbation phase].
Clinical and laboratory studies have been performed in 120 patients with chronic obstructive diseases of the lung (CODL) and in 35 healthy individuals in order to determine the content of different phospholipid fractions in the platelet membranes and their proportions at the beginning of their medical rehabilitation after pulmonological hospital treatment (recurrent exacerbation). It has been found that membranosystemic disorders in CODL represent a major pathogenetic link in the vicious circle of disease progression and the routine therapy is low effective and has no membrane-repairing effect. This makes it necessary to develop and search for new pathogenetic treatments of CODL, which are to exert a membranotropic effects on the whole body.
Zoirova
N I
NI
Chekina
E B
EB
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D003627:Data Interpretation, Statistical; D006801:Humans; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood*; D029424:Pulmonary Disease, Chronic Obstructive / Q000097:blood* / Q000503:physiopathology / Q000534:rehabilitation; D012008:Recurrence; D013147:Spirometry
D010743:Phospholipids