title: Paternity testing using Y-STR haplotypes: assigning a probability for paternity in cases of mutations.
abstract: In parentage testing with male children, Y-chromosomal STR evidence is gaining more and more importance. In some cases, multilocus haplotypes of related persons can differ at a single locus due to a mutation. In this work, a likelihood approach is presented for the calculation of a probability for paternity under consideration of a single mutation event on the Y-chromosome. The new methodology is applied to two case examples.
authors.affiliation: Institute of Legal Medicine, Ludwigs-Maximilans-Universität, München, Germany. burkhard.rolf@rechts.med.uni-muenchen.de
authors.forename: B
authors.initials: B
authors.lastname: Rolf
authors.forename: W
authors.initials: W
authors.lastname: Keil
authors.forename: B
authors.initials: B
authors.lastname: Brinkmann
authors.forename: L
authors.initials: L
authors.lastname: Roewer
authors.forename: R
authors.initials: R
authors.lastname: Fimmers
mesh_terms: D002648:Child; D016172:DNA Fingerprinting / Q000379:methods*; D005260:Female; D005554:Forensic Medicine; D006239:Haplotypes; D006801:Humans; D008297:Male; D009154:Mutation; D010334:Paternity; D010375:Pedigree; D020080:Tandem Repeat Sequences / Q000235:genetics*; D014998:Y Chromosome