[Celiac disease can be associated with severe neurological symptoms. Analysis of gliadin antibodies should be considered in suspected cases].
Celiac disease can be associated with a wide spectrum of neurological and psychiatric symptoms (cerebellar ataxia, neuromuscular manifestations, epilepsy, dementia), even in the absence of malabsorption or gastrointestinal symptoms. The case of a 72-year-old man with a rapidly progressive, lethal encephalopathy secondary to celiac disease is reported, together with a review of documented neurological symptoms in celiac disease. The aetiology of these neurological symptoms is unknown, although immunological mechanisms are suspected.
Bruzelius
M
M
Medicinkliniken, Område medicin, Ostersunds lasarett.
Liedholm
L J
LJ
Hellblom
M
M
D000368:Aged; D000906:Antibodies / Q000032:analysis*; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D002524:Cerebellar Ataxia / Q000175:diagnosis / Q000209:etiology / Q000276:immunology; D003937:Diagnosis, Differential; D005684:Gait; D005903:Gliadin / Q000276:immunology*; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D009468:Neuromuscular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology
D000906:Antibodies; D005903:Gliadin