title: The TF:VIIa complex: clinical significance, structure-function relationships and its role in signaling and metastasis.
authors.affiliation: The Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
authors.forename: W
authors.initials: W
authors.lastname: Konigsberg
authors.forename: D
authors.initials: D
authors.lastname: Kirchhofer
authors.forename: M A
authors.initials: MA
authors.lastname: Riederer
authors.forename: Y
authors.initials: Y
authors.lastname: Nemerson
mesh_terms: D000818:Animals; D001665:Binding Sites; D001777:Blood Coagulation / Q000502:physiology; D002318:Cardiovascular Diseases / Q000097:blood / Q000503:physiopathology; D002384:Catalysis; D002986:Clinical Trials as Topic; D004285:Dogs; D016228:Endothelial Growth Factors / Q000096:biosynthesis / Q000235:genetics; D004789:Enzyme Activation; D015942:Factor VIIa / Q000737:chemistry / Q000502:physiology*; D005786:Gene Expression Regulation; D006098:Granulocytes / Q000502:physiology; D006801:Humans; D007700:Kinetics; D008222:Lymphokines / Q000096:biosynthesis / Q000235:genetics; D020935:MAP Kinase Signaling System / Q000502:physiology; D046911:Macromolecular Substances; D008958:Models, Molecular; D009362:Neoplasm Metastasis / Q000503:physiopathology*; D009363:Neoplasm Proteins / Q000502:physiology; D011485:Protein Binding; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D015398:Signal Transduction / Q000502:physiology*; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D013816:Thermodynamics; D013925:Thromboplastin / Q000737:chemistry / Q000502:physiology*; D013927:Thrombosis / Q000503:physiopathology; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
chemical_list: D016228:Endothelial Growth Factors; D008222:Lymphokines; D046911:Macromolecular Substances; D009363:Neoplasm Proteins; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D013925:Thromboplastin; D015942:Factor VIIa