Cyclic red blood cell destruction in thalassemia.
A retrospective analysis of time series of hemoglobin (Hb) destruction of 24 children (11 males and 13 females) with thalassemia from the age of 6 to 12 years showed that the Hb destruction rate typically oscillated with an average period of 50 days. A possible relation between the periodism and the severity of the disease is also suggested.
Giani
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U
Department of Preventive Medical Sciences, Faculty of Medicine, University of Naples, Italy. ugiani@cds.unina.it
Filosa
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D001803:Blood Transfusion; D002648:Child; D004912:Erythrocytes / Q000502:physiology*; D005260:Female; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D008297:Male; D010507:Periodicity; D012189:Retrospective Studies; D013789:Thalassemia / Q000097:blood* / Q000503:physiopathology / Q000628:therapy; D013997:Time Factors
D006454:Hemoglobins