title: Pyoderma gangrenosum in two siblings: a familial predisposition.
abstract: We report pyoderma gangrenosum in two siblings with onset during childhood and no associated systemic abnormalities. The patients were born of nonconsanguineous, healthy parents. Treatment with oral corticosteroids produced an excellent clinical response, followed by recurrence after cessation of therapy. Steroids were restarted in combination with dapsone to prevent further recurrence.
authors.affiliation: Department of Dermatology and Venereology, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India. shaifalikhandpur@hotmail.com
authors.forename: S
authors.initials: S
authors.lastname: Khandpur
authors.forename: S
authors.initials: S
authors.lastname: Mehta
authors.forename: B S
authors.initials: BS
authors.lastname: Reddy
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001707:Biopsy, Needle; D002648:Child; D004423:Ear; D005260:Female; D005500:Follow-Up Studies; D005528:Foot; D006801:Humans; D008297:Male; D009679:Nuclear Family; D017511:Pyoderma Gangrenosum / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology*; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones