title: A case of infectious tuberculosis on two long-haul aircraft flights: contact investigation.
abstract: OBJECTIVE
  During a five-week period in 1996, a passenger with highly infectious tuberculosis travelled on five long-haul aircraft flights. We investigated passengers and crew on two of these flights to identify whether transmission of Mycobacterium tuberculosis had occurred.
  
  
  METHODS
  Crew and passengers were identified from airline and immigration records. Contacts were notified of their exposure and invited to attend their local public health clinic. At the clinic, a questionnaire was administered by a public health worker, and a Mantoux skin test was performed. When indicated, a second test was carried out twelve weeks later. Test positivity and conversion were defined according to the 1996 New Zealand tuberculosis control guidelines.
  
  
  RESULTS
  Data were obtained on 206 (87%) of the 238 contacts. Twenty four contacts had a positive Mantoux test result, four of which were conversions. All of these contacts had at least one other major risk factor for a positive result, such as a previous BCG vaccination (n=17) or having lived in a country in which tuberculosis is endemic (n=15). To our knowledge, no contacts have subsequently developed tuberculosis disease.
  
  
  CONCLUSIONS
  The investigation produced inconclusive evidence about the hypothesis that Mycobacterium tuberculosis was transmitted on one or both of these flights.
authors.affiliation: Clinical Trials Research Unit, University of Auckland.
authors.forename: G
authors.initials: G
authors.lastname: Whitlock
authors.forename: L
authors.initials: L
authors.lastname: Calder
authors.forename: H
authors.initials: H
authors.lastname: Perry
mesh_terms: D000328:Adult; D000368:Aged; D000401:Aircraft; D005260:Female; D006801:Humans; D008875:Middle Aged; D014195:Travel; D014374:Tuberculin Test; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000635:transmission*