title: Oesophageal Doppler monitoring overestimates cardiac output during lumbar epidural anaesthesia.
abstract: Oesophageal Doppler monitoring (ODM) has been advocated as a non-invasive means of measuring cardiac output (CO). However, its reliance upon blood flow measurement in the descending aorta to estimate CO is susceptible to error if blood flow is redistributed between the upper and lower body. We hypothesize that lumbar epidural anesthesia (LEA), which causes blood flow redistribution, causes errors in CO estimates. We compared ODM with thermodilution (TD) measurements in fourteen patients under general anaesthesia for radical prostatectomy, who had received an epidural catheter at the intervertebral level L2-L3. Coupled measurements of CO by means of the TD and ODM techniques were performed at baseline (general anaesthetic only) and after epidural administration of 10 ml of 0.25% bupivacaine. The two methods were compared using Bland-Altman analysis: before LEA there was a bias of -0.89 litre min(-1) with limits of agreement ranging between -2.67 and +0.88 litre min(-1). Following lumbar sympathetic block, bias became positive (+0.55 litre min(-1)) and limits of agreement increased to -3.21 and +4.30 litre min(-1). ODM measured a greater increase in CO after LEA (delta=+1.71 (1.19) litre min(-1) (mean (SD)) compared with TD (delta=+0.51 (0.70) litre min(-1)). We conclude that following LEA, measurements with the Oesophageal Doppler Monitor II overestimate CO and show unacceptably high variability. Blood flow redistribution may limit the value of ODM.
authors.affiliation: Department of Anaesthesiology, University Hospitals, Katholieke Universiteit Leuven, U. Z. Gasthuisberg, Leuven, Belgium.
authors.forename: H A
authors.initials: HA
authors.lastname: Leather
authors.forename: P F
authors.initials: PF
authors.lastname: Wouters
mesh_terms: D000368:Aged; D000767:Anesthesia, Epidural; D019162:Anesthetics, Combined; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D017548:Echocardiography, Transesophageal; D006801:Humans; D008161:Lumbosacral Region; D008297:Male; D008875:Middle Aged; D015742:Propofol; D012680:Sensitivity and Specificity; D017409:Sufentanil; D014673:Vecuronium Bromide
chemical_list: D019162:Anesthetics, Combined; D014673:Vecuronium Bromide; D017409:Sufentanil; D015742:Propofol