New bioactive cyclopentenone derivatives as inhibitors of the IL-6 dependent signal transduction.
Weidler
M
M
Institute für Biotechnologie und Wirkstoff-Forschung e V. (IBWF), Kaiserslautern, Germany.
Rether
J
J
Anke
T
T
Erkel
G
G
Sterner
O
O
D001203:Ascomycota / Q000378:metabolism; D006528:Carcinoma, Hepatocellular; D003517:Cyclopentanes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D015870:Gene Expression / Q000187:drug effects; D017930:Genes, Reporter; D006801:Humans; D015850:Interleukin-6 / Q000494:pharmacology*; D019169:Jurkat Cells; D008113:Liver Neoplasms; D009682:Magnetic Resonance Spectroscopy; D015398:Signal Transduction / Q000187:drug effects*; D014407:Tumor Cells, Cultured; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
D003517:Cyclopentanes; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; C013905:cyclopentenone