Inhibition of HIV replication by A77 1726, the active metabolite of leflunomide, in combination with pyrimidine nucleoside reverse transcriptase inhibitors.
Hossain
M M
MM
Margolis
D M
DM
D000814:Aniline Compounds / Q000097:blood / Q000494:pharmacology*; D019380:Anti-HIV Agents / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D003437:Crotonates; D006678:HIV / Q000187:drug effects / Q000502:physiology*; D016655:HIV Core Protein p24 / Q000096:biosynthesis; D018023:HIV Seronegativity; D006801:Humans; D006885:Hydroxybutyrates / Q000097:blood / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007555:Isoxazoles / Q000097:blood / Q000494:pharmacology*; D000077339:Leflunomide; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D009570:Nitriles; D018894:Reverse Transcriptase Inhibitors / Q000097:blood / Q000627:therapeutic use*; D014052:Toluidines; D014779:Virus Replication / Q000187:drug effects*; D015215:Zidovudine / Q000494:pharmacology*
D000814:Aniline Compounds; D019380:Anti-HIV Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D003437:Crotonates; D016655:HIV Core Protein p24; D006885:Hydroxybutyrates; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; D018894:Reverse Transcriptase Inhibitors; D014052:Toluidines; C527525:teriflunomide; D015215:Zidovudine; D000077339:Leflunomide