A simple enantioselective synthesis of serratenediol.
[reaction: see text] A short synthesis of serratenediol is described, which involves a number of powerful key steps including (1) catalytic enantioselective syntheses of the phenyl sulfone and acylsilane shown above, (2) their coupling, and (3) further stereoselective cationic cyclizations.
Zhang
J
J
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Corey
E J
EJ
D013237:Stereoisomerism; D014315:Triterpenes / Q000138:chemical synthesis*
D014315:Triterpenes; C438932:serratenediol