Radial glial cells. are they really glia?
During the development of the cerebral cortex, radial glia serve as a scaffold to support and direct neurons during their migration. This view is now changing in the light of emerging evidence showing that these cells have a much more dynamic and diverse role. A recent series of studies has provided strong support for their role as precursor cells in the ventricular zone that generate cortical neurons and glia, in addition to providing migration guidance.
Parnavelas
J G
JG
Department of Anatomy and Developmental Biology, University College London, London WC1E 6BT, United Kingdom. j.parnavelas@ucl.ac.uk
Nadarajah
B
B
D000818:Animals; D001253:Astrocytes / Q000737:chemistry / Q000145:classification* / Q000166:cytology; D015415:Biomarkers / Q000032:analysis; D001717:Birds / Q000033:anatomy & histology / Q000196:embryology; D002454:Cell Differentiation; D019070:Cell Lineage; D002490:Central Nervous System / Q000166:cytology* / Q000196:embryology; D002540:Cerebral Cortex / Q000166:cytology / Q000196:embryology; D002642:Chick Embryo; D017930:Genes, Reporter; D005904:Glial Fibrillary Acidic Protein / Q000235:genetics; D049452:Green Fluorescent Proteins; D006801:Humans; D008164:Luminescent Proteins / Q000032:analysis; D008322:Mammals / Q000033:anatomy & histology / Q000196:embryology; D051379:Mice; D008822:Mice, Transgenic; D009419:Nerve Tissue Proteins / Q000032:analysis; D009474:Neurons / Q000166:cytology; D051381:Rats; D011993:Recombinant Fusion Proteins / Q000032:analysis; D013234:Stem Cells / Q000166:cytology
D015415:Biomarkers; D005904:Glial Fibrillary Acidic Protein; D008164:Luminescent Proteins; D009419:Nerve Tissue Proteins; D011993:Recombinant Fusion Proteins; D049452:Green Fluorescent Proteins