[Effect of total saponins of Panax notoginseng (TSPNS) on myocardial intracellular Ca2+ and activity of calcium pump of membrane of sarcoplasmic reticulum in SHR].
A comparative study was conducted on the action of TSPNS, NS and Captopril in treating SHR, with WKY of similar ages taken as normal control. The results demonstrate that TSPNS helps increase the effect of calcium pump on the membrane of sarcoplasmic reticulum, decrease the myocardial intracellular Ca2+ and reduce the mass of the left ventricular muscle.
Feng
P
P
Zhejiang Traditional Chinese Medical College, Affiliated Hospital, Hangzhou 310006.
Jiang
H
H
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D009206:Myocardium / Q000166:cytology / Q000378:metabolism*; D005894:Panax / Q000737:chemistry*; D010946:Plants, Medicinal; D011897:Random Allocation; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D012519:Sarcoplasmic Reticulum / Q000378:metabolism
D012503:Saponins; D000252:Calcium-Transporting ATPases; D002118:Calcium