title: Update on the diagnosis and treatment of disorders of calcium regulation.
abstract: The availability of PTH, iCa, PTHrP, and 25OHD assays for evaluation of calcium abnormalities in companion animals has been well received [table: see text] by clinicians and diagnosticians. Use of these assays has heightened awareness that some of these disorders are more common than originally thought. Also, there is added insight of alterations of calcium homeostasis as a consequence of other illness or environmental factors such as diet. Animal counterparts of other disorders of calcium metabolism in people are likely to be identified, and use of these assays should play a significant role. As already emphasized, the foundation of using [table: see text] these assays is first assessing whether the calcium abnormality is of a parathyroid-dependent or parathyroid-independent classification.
authors.affiliation: Diagnostic Endocrinology Section, Animal Health Diagnostic Laboratory, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
authors.forename: K R
authors.initials: KR
authors.lastname: Refsal
authors.forename: A L
authors.initials: AL
authors.lastname: Provencher-Bolliger
authors.forename: P A
authors.initials: PA
authors.lastname: Graham
authors.forename: R F
authors.initials: RF
authors.lastname: Nachreiner
mesh_terms: D000818:Animals; D002118:Calcium / Q000097:blood; D002128:Calcium Metabolism Disorders / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis* / Q000628:therapy; D002415:Cats; D004283:Dog Diseases / Q000175:diagnosis* / Q000628:therapy; D004285:Dogs; D020022:Genetic Predisposition to Disease; D010279:Parathyroid Diseases / Q000209:etiology / Q000662:veterinary*; D010375:Pedigree; D014807:Vitamin D / Q000008:administration & dosage
chemical_list: D014807:Vitamin D; D002118:Calcium