title: Bamboo node: primary vocal fold lesion as evidence of autoimmune disease.
abstract: Descriptions of vocal fold lesions related to autoimmune diseases are rare in the literature, and focus mainly on rheumatoid nodules. This is the first report in which autoimmune diseases were promptly suspected by the observation of a unique white transverse submucosal lesion in the vocal fold during clinical examination. This lesion, reported only in autoimmune disease, has been called the bamboo node and its features are different from those of rheumatoid nodules. We report here on two patients who did not have a diagnosis of systemic disease before investigation of their main complaint of hoarseness. At the patients' first visit, vocal fold bamboo nodes were seen in the vocal fold and the otolaryngologist suspected the presence of an autoimmune disease. We requested clinical investigation to clarify our suspicion that there was an underlying systemic disease. After the investigation, both patients were shown to have autoimmune disease, Sjögren's syndrome and systemic lupus erythematous, respectively. This paper emphasizes the important role of the otolaryngologist in the detection of these unique lesions in the vocal folds through the conventional laryngeal methods. These methods consisted of direct observation with a rigid laryngeal endoscope and investigation of the patient's distinctive vibratory pattern by means of laryngeal stroboscopy. The method of treatment we used to obtain the best outcome in terms of voice improvement is also discussed.
authors.affiliation: Department of Otolaryngology, University of Tokyo, Japan. murano@m.u-tokyo.ac.jp
authors.forename: E
authors.initials: E
authors.lastname: Murano
authors.forename: Y
authors.initials: Y
authors.lastname: Hosako-Naito
authors.forename: N
authors.initials: N
authors.lastname: Tayama
authors.forename: T
authors.initials: T
authors.lastname: Oka
authors.forename: M
authors.initials: M
authors.lastname: Miyaji
authors.forename: M
authors.initials: M
authors.lastname: Kumada
authors.forename: S
authors.initials: S
authors.lastname: Niimi
mesh_terms: D000328:Adult; D005260:Female; D006685:Hoarseness / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology*; D008875:Middle Aged; D012720:Severity of Illness Index; D012859:Sjogren's Syndrome / Q000150:complications* / Q000276:immunology*; D014827:Vocal Cords / Q000473:pathology*