title: [A case of transitional cell carcinoma of the urinary bladder with high serum level of CEA and CA19-9].
abstract: An 85-year-old male with asymptomatic gross hematuria was diagnosed with invasive bladder tumor, transitional cell carcinoma grade 3. Serum levels of CEA and CA19-9 were elevated and histological examination revealed expression of both markers in the cytoplasm of cancer cells. Out of therapeutic options, intra-arterial chemotherapy and radiotherapy were selected because of his age. During the treatment, serum levels of CEA and CA19-9 decreased along with reduction of tumor size. These serum markers have been reported to be elevated in 10 to 60% of patients with bladder tumor and are useful markers for evaluation of the treatment as suggested in the present case.
authors.affiliation: Department of Urology, Institute of Clinical Medicine, University of Tsukuba.
authors.forename: H
authors.initials: H
authors.lastname: Inai
authors.forename: T
authors.initials: T
authors.lastname: Shimazui
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: A
authors.initials: A
authors.lastname: Yamauchi
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: H
authors.initials: H
authors.lastname: Takeshima
authors.forename: H
authors.initials: H
authors.lastname: Akaza
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000097:blood*; D018395:CA-19-9 Antigen / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood*; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000276:immunology*
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen