title: Low complication rate during intraperitoneal therapy through a totally implanted peritoneal access port in patients with ovarian cancer.
abstract: Fifty-three patients with histologically proven ovarian cancer were treated with intraperitoneally administered cisplatin or human recombinant interferon-alpha through a totally implanted peritoneal access port. A total of 281 treatment courses were given. No complications related to surgical implantation of the port were seen. Infectious complications, intra-abdominal problems or subcutaneous drug extravasation did not occur. In two patients the number of treatment courses was limited due to inflow obstruction. A totally implanted peritoneal access port proves to be a reliable route for the intraperitoneal treatment of patients with ovarian cancer. The strict aseptic technique we used contributes to its safety by preventing intra-abdominal infections.
authors.affiliation: Department of Medical Oncology and Gynaecology, University Hospital Groningen, The Netherlands.
authors.forename: A.G.
authors.initials: AG
authors.lastname: Nanninga
authors.forename: P.H.B.
authors.initials: PH
authors.lastname: Willemse
authors.forename: H.
authors.initials: H
authors.lastname: Boonstra
authors.forename: E.G.E.
authors.initials: EG
authors.lastname: De Vries