title: Inverted papilloma: a review of 53 cases.
abstract: OBJECTIVE
  To assess the surgical management of patients with inverted nasal papilloma over a 14-year period.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Tertiary health care center.
  
  
  RESULTS
  Fifty-three patients (38 males, 15 females) with an average age of 49.8 years were treated. Overall recurrence rate was 28% and a malignant association of 9% was shown. Recurrence rates varied from 27% in patients with more extensive disease involvement treated by lateral rhinotomy and medial maxillectomy, to 30% in patients with less extensive disease treated conservatively. Of the 5 patients with associated malignancy, 3 (6% of all patients) are likely to have undergone malignant transformation.
  
  
  CONCLUSIONS
  Aggressive initial management remains the therapeutic aim in this condition.
authors.affiliation: Department of Otolaryngology, University of Cape Town, Groote Schuur Hospital, Observatory, South Africa.
authors.forename: M A
authors.initials: MA
authors.lastname: Thorp
authors.forename: M F
authors.initials: MF
authors.lastname: Oyarzabal-Amigo
authors.forename: J H
authors.initials: JH
authors.lastname: du Plessis
authors.forename: S L
authors.initials: SL
authors.lastname: Sellars
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009364:Neoplasm Recurrence, Local; D009669:Nose Neoplasms / Q000601:surgery*; D018308:Papilloma, Inverted / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies