title: Sequence structure of 12 novel Y chromosome microsatellites and PCR amplification strategies.
abstract: In this work, we present sequencing data for 12 recently reported Y STR loci (DYS434, DYS435, DYS436, DYS437, DYS438, DYS439, GATA A10, GATA 7.1, GATA 7.2, GATA C4, GATA H4, GATA A4), as well as the PCR multiplex strategies we implemented for their detection. Sequenced allelic ladders were constructed and a nomenclature for these new systems is proposed based on the sequence structure and following ISFG recommendations.GATA A4 and DYS439 are likely the same STR. They have the same STR structure and the alleles are always the same in the same individuals.Sequence polymorphisms were observed in the GATA C4 and DYS437 STRs. The variation in DYS437 was associated with a specific population group and is very interesting not only for forensic genetics but also for anthropological studies.
authors.affiliation: Institute of Legal Medicine, University of Santiago de Compostela, E-15705 Santiago de Compostela, Galicia, Spain.
authors.forename: A
authors.initials: A
authors.lastname: González-Neira
authors.forename: M
authors.initials: M
authors.lastname: Elmoznino
authors.forename: M V
authors.initials: MV
authors.lastname: Lareu
authors.forename: P
authors.initials: P
authors.lastname: Sánchez-Diz
authors.forename: L
authors.initials: L
authors.lastname: Gusmão
authors.forename: M
authors.initials: M
authors.lastname: Prinz
authors.forename: A
authors.initials: A
authors.lastname: Carracedo
mesh_terms: D000483:Alleles; D001483:Base Sequence; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences; D009626:Terminology as Topic; D014998:Y Chromosome / Q000235:genetics*