Adding two new drug classes improves outcome in salvage therapy.
In patients experiencing treatment failure on an NRTI regimen, adding both a PI and an NNRTI to salvage therapy resulted in significant virologic improvements compared with adding a drug from either class alone.
Havlir
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University of California, San Diego, USA.
D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D018894:Reverse Transcriptase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D016879:Salvage Therapy; D016896:Treatment Outcome; D019562:Viral Load
D019380:Anti-HIV Agents; D018894:Reverse Transcriptase Inhibitors