title: Partial alignment of biomolecules: an aid to NMR characterization.
abstract: Partial alignment of biomolecules in solution has added a new dimension to structural investigation by high-resolution NMR methods. Applications to proteins, nucleic acids and carbohydrates now abound. Limitations initially associated with compatibility of biomolecules with the liquid-crystal media commonly used to achieve alignment have begun to disappear. This is, in part, a result of the introduction of a wide variety of new media. Future applications to biologically important problems such as the structural organization of multi-domain proteins and multi-protein assemblies look very promising.
authors.affiliation: Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, USA. jpresteg@ccrc.uga.edu
authors.forename: J H
authors.initials: JH
authors.lastname: Prestegard
authors.forename: A I
authors.initials: AI
authors.lastname: Kishore
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D009696:Nucleic Acids / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment
chemical_list: D002241:Carbohydrates; D009696:Nucleic Acids; D010455:Peptides; D011506:Proteins