title: Non-invasive distension of the small bowel for magnetic-resonance imaging.
abstract: Magnetic resonance enteroclysis is a promising technique that allows assessment of the small bowel but needs invasive nasoduodenal intubation. We propose a non-invasive distension method for magnetic-resonance imaging (MRI) in which ispaghula, dissolved in an aqueous solution with meglumine gadoterate taken orally over 4 h forms a viscous hydrogel within the intestinal lumen. MRI results from ten volunteers showed good luminal distension, constant signal homogeneity, optimum demarcation of the bowel content from surrounding tissues, and a low rate of artefacts. Our method permits non-invasive high quality MRI of the small bowel.
authors.forename: M A
authors.initials: MA
authors.lastname: Patak
authors.forename: J M
authors.initials: JM
authors.lastname: Froehlich
authors.forename: C
authors.initials: C
authors.lastname: von Weymarn
authors.forename: M A
authors.initials: MA
authors.lastname: Ritz
authors.forename: C L
authors.initials: CL
authors.lastname: Zollikofer
authors.forename: K
authors.initials: K
authors.lastname: Wentz
mesh_terms: D000328:Adult; D002400:Cathartics / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis; D007421:Intestine, Small / Q000187:drug effects*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011620:Psyllium / Q000494:pharmacology*
chemical_list: D002400:Cathartics; D011620:Psyllium