title: [Stereotactic vacuum core biopsy of clustered microcalcifications classified as B1-RADS 3].
abstract: OBJECTIVE
  Evaluation of stereotactic vacuum core biopsy of clustered microcalcifications categorized as BI-RADS 3.
  
  
  METHODS
  86 patients with microcalcifications BI-RADS 3 (probably benign, < 3% malignant) underwent a stereotactic vacuum core biopsy (Mammotome, Fa. Ethicon Endo-Surgery Breast Care) using a digital stereotactic unit (Mammotest, Fa. Fischer Imaging). The removal of the calcifications was judged by two radiologists in consensus and classified as complete (100%), major (55-99%) or incomplete (< 50%).
  
  
  RESULTS
  4/86 patients could not be evaluated by vacuum core biopsy due to the localization of the microcalcifications close to the skin or lack of detection. In 40/82 cases a complete, in 38/82 a major, and in 4/82 a incomplete removal was achieved. Histology revealed 67 cases of fibrocystic changes, 4 papillomas, 4 fibroadenomas, 4 cases of atypical ductal hyperplasia (ADH), and 3 ductal carcinomas in situ (DCIS), one of these with a minimal-invasive tumor component. Patient with ADH were advised to undergo surgical biopsy. Histology revealed complete removal. 7 patients had complications or side-effects.
  
  
  CONCLUSIONS
  Percutaneous vacuum core biopsy is a reliable minimal-invasive diagnostic method to come to the final diagnosis in patients with clustered microcalcifications categorized BI-RADS 3. However, if malignancy is proven (about 4% of our cases) an open biopsy is necessary.
authors.affiliation: Abt. Röntgendiagnostik I, Klinikum der Georg-August-Universität, Göttingen. soben@med.uni-goettingen.de
authors.forename: S
authors.initials: S
authors.lastname: Obenauer
authors.forename: U
authors.initials: U
authors.lastname: Fischer
authors.forename: F
authors.initials: F
authors.lastname: Baum
authors.forename: S
authors.initials: S
authors.lastname: Dammert
authors.forename: L
authors.initials: L
authors.lastname: Füzesi
authors.forename: E
authors.initials: E
authors.lastname: Grabbe
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods*; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002114:Calcinosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D006965:Hyperplasia; D008279:Magnetic Resonance Imaging; D008327:Mammography / Q000379:methods*; D008875:Middle Aged; D018300:Papilloma, Intraductal / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013238:Stereotaxic Techniques; D013997:Time Factors