title: [State of local immunity in patients with inflammatory diseases of the spine].
abstract: The paper presents the results of examination of spinal fluid in tuberculous spondylitis (n = 83), its sequelae (n = 58), spinal osteomyelitis (n = 25) for the levels of tuberculosis antibodies (TAb) by applying the routine enzyme immunoassay, specially adapted to this biological object, and immunoglobulins. A relationship was found between TAb detection and the rate of the process and the severity of a spinal cord lesion. Forty one patients had severe spinal cord disorders (paraplegia and deep paraparesis). To detect TAb in CF is shown to be of differential diagnostic value. There is new evidence for impaired blood-brain and immunological barriers in active tuberculosis in the spine with spinal cord compression.
authors.forename: R I
authors.initials: RI
authors.lastname: Shenderova
authors.forename: V V
authors.initials: VV
authors.lastname: Oleĭnik
authors.forename: O A
authors.initials: OA
authors.lastname: Iakunova
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000097:blood / Q000134:cerebrospinal fluid; D007074:Immunoglobulin G / Q000097:blood / Q000134:cerebrospinal fluid; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000276:immunology; D013117:Spinal Cord Compression / Q000209:etiology; D014399:Tuberculosis, Spinal / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G