Bitemporal epileptiform discharges induced by bupropion: a case report.
We report the case of a 44-year-old right-handed woman who experienced her first convulsion while taking bupropion. Electroencephalography showed frequent bilateral independent temporal lobe epileptiform discharges that resolved when bupropion was discontinued. This is the first well-documented case of epileptiform discharges induced by bupropion in humans.
Shah
G D
GD
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Hirsch
L J
LJ
D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects*; D016642:Bupropion / Q000009:adverse effects*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D012640:Seizures / Q000139:chemically induced* / Q000503:physiopathology; D013702:Temporal Lobe / Q000187:drug effects / Q000503:physiopathology*
D018687:Antidepressive Agents, Second-Generation; D016642:Bupropion