Sequential multilocus fluorescence in situ hybridization can detect complex patterns of increased gene dosage at the single cell level in tissue sections.
Walch
A
A
Institute of Pathology, Technische Universität München, Munich, Germany. axel.walch@lrz.tum.de
Bink
K
K
Hutzler
P
P
Böwering
K
K
Letsiou
I
I
Zitzelsberger
H
H
Braselmann
H
H
Stein
H
H
Höfler
H
H
Werner
M
M
D000818:Animals; D018628:Gene Dosage; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods; D008867:Microtomy