Mechanisms of surfactant exocytosis in alveolar type II cells in vitro and in vivo.
Surfactant secretion must be regulated to maintain a low surface tension in the lung during various conditions such as exercise. In vitro studies reveal a slow, unique exocytotic process at the interface of stimulated and constitutive exocytosis. The exocytotic mechanisms and sites of regulation in vivo, however, are still poorly understood.
Dietl
P
P
Department of Physiology, University of Innsbruck, A-6020 Innsbruck, Austria.
Haller
T
T
Mair
N
N
Frick
M
M
D000818:Animals; D005089:Exocytosis / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D011650:Pulmonary Alveoli / Q000166:cytology / Q000378:metabolism*; D011663:Pulmonary Surfactants / Q000378:metabolism*
D011663:Pulmonary Surfactants