title: Active constituents isolated from Psoralea glandulosa L. with antiinflammatory and antipyretic activities.
abstract: The antiinflammatory and antipyretic activities of the petroleum ether extract (PEE), dichloromethane extract (DME) and methanol extract (ME1) of the aerial part of Psoralea glandulosa L. (Papilionaceae) were studied. The bioactivity-guided fractionation of the active extracts yielded the isolation of bakuchiol (Bk) from the petroleum ether as the active compound, cyclobakuchiols A and B (Cbk), and angelicin (Ang) from DME.
authors.affiliation: Laboratory of Pharmacognosy, Faculty of Pharmaceutical and Chemical Sciences, University of Chile, PO Box 233, 1-, Santiago, Chile.
authors.forename: C N
authors.initials: CN
authors.lastname: Backhouse
authors.forename: C L
authors.initials: CL
authors.lastname: Delporte
authors.forename: R E
authors.initials: RE
authors.lastname: Negrete
authors.forename: S
authors.initials: S
authors.lastname: Erazo
authors.forename: A
authors.initials: A
authors.lastname: Zuñiga
authors.forename: A
authors.initials: A
authors.lastname: Pinto
authors.forename: B K
authors.initials: BK
authors.lastname: Cassels
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D004987:Ethers; D005260:Female; D006168:Guinea Pigs; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D000432:Methanol; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D029907:Psoralea / Q000737:chemistry*; D011817:Rabbits; D012997:Solvents
chemical_list: D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004987:Ethers; D010936:Plant Extracts; D012997:Solvents; D000432:Methanol