title: An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy.
abstract: A 32-year-old woman presenting with a rapidly progressive ALS-like syndrome was found to be HIV positive with a CD4 count of 44/mm(3). The patient recovered completely during 1 year after treatment with nelfinavir, zidovudine, and lamivudine, and recovery is sustained nearly 4 years later. Recovery was accompanied by HIV RNA becoming undetectable in plasma and CSF.
authors.affiliation: Department of Neurology, Beth Israel Medical Center, New York, NY 10003, USA. dmacgow@bethisraelny.org
authors.forename: D J
authors.initials: DJ
authors.lastname: MacGowan
authors.forename: S N
authors.initials: SN
authors.lastname: Scelsa
authors.forename: M
authors.initials: M
authors.lastname: Waldron
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D019259:Lamivudine / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D016472:Motor Neuron Disease / Q000175:diagnosis / Q000188:drug therapy*; D019888:Nelfinavir / Q000627:therapeutic use; D009460:Neurologic Examination / Q000187:drug effects; D016896:Treatment Outcome; D015215:Zidovudine / Q000627:therapeutic use
chemical_list: D019380:Anti-HIV Agents; D019259:Lamivudine; D015215:Zidovudine; D019888:Nelfinavir