The beta-hexosaminidase story in Toronto: from enzyme structure to gene mutation.
Mahuran
D J
DJ
The Research Institute, The Hospital for Sick Children and Department of Laboratory Medicine and Pathobiology University of Toronto, Ontario, Canada. hex@sickkids.on.ca
Gravel
R A
RA
D000595:Amino Acid Sequence; D002170:Canada; D005260:Female; D049673:History, 20th Century; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009154:Mutation; D010375:Pedigree; D011499:Protein Processing, Post-Translational; D017386:Sequence Homology, Amino Acid; D013329:Structure-Activity Relationship; D013661:Tay-Sachs Disease / Q000201:enzymology / Q000235:genetics / Q000266:history*; D001619:beta-N-Acetylhexosaminidases / Q000737:chemistry / Q000235:genetics / Q000266:history*
D001619:beta-N-Acetylhexosaminidases