title: Revascularization of an immature permanent tooth with  apical periodontitis and sinus tract.
abstract: A necrotic immature mandibular second premolar with periapical involvement in a 13-year-old patient was treated. Instead of the standard root canal treatment protocol and apexification, antimicrobial agents were used in the canal, after which the canal was left empty. Radiographic examination showed the start of apical closure 5 months after the completion of the antimicrobial protocol. Thickening of the canal wall and complete apical closure was confirmed 30 months after the treatment, indicating the revascularization potential of a young permanent tooth pulp into a bacteria-free root canal space.
authors.affiliation: Department of Dentistry, Tohoku Welfare Pension Hospital, Sendai, Japan.
authors.forename: S I
authors.initials: SI
authors.lastname: Iwaya
authors.forename: M
authors.initials: M
authors.lastname: Ikawa
authors.forename: M
authors.initials: M
authors.lastname: Kubota
mesh_terms: D000293:Adolescent; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001641:Bicuspid / Q000293:injuries; D002939:Ciprofloxacin / Q000627:therapeutic use; D003751:Dental Fistula / Q000209:etiology* / Q000628:therapy; D003782:Dental Pulp / Q000098:blood supply* / Q000293:injuries; D003790:Dental Pulp Necrosis / Q000150:complications* / Q000209:etiology / Q000601:surgery; D003809:Dentin, Secondary / Q000378:metabolism; D005260:Female; D006801:Humans; D008334:Mandible; D008795:Metronidazole / Q000627:therapeutic use; D018919:Neovascularization, Physiologic; D010485:Periapical Periodontitis / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D011670:Pulpectomy; D014082:Tooth Fractures / Q000150:complications* / Q000503:physiopathology
chemical_list: D000891:Anti-Infective Agents, Local; D008795:Metronidazole; D002939:Ciprofloxacin