title: Is coasting effective for preventing ovarian hyperstimulation syndrome in patients receiving a gonadotropin-releasing hormone antagonist during an in vitro fertilization cycle?
abstract: OBJECTIVE
  To report two cases of coasting during receipt of GnRH antagonists.
  
  
  METHODS
  Case report.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  One 27-year-old and one 28-year-old woman, both with risk factors for the ovarian hyperstimulation syndrome (OHSS).
  
  
  METHODS
  Two IVF treatments during which hMG treatment was stopped until E2 decreased to a safer level during receipt of GnRH antagonist.
  
  
  METHODS
  Development of OHSS and pregnancy.
  
  
  RESULTS
  Embryos were transferred in both women. Neither woman developed OHSS and one ongoing pregnancy was obtained.
  
  
  CONCLUSIONS
  Coasting is feasible when a GnRH antagonist is used during IVF. Further studies are needed to evaluate its preventive role in OHSS.
authors.affiliation: IVF Center, Department of Obstetrics and Gynecology, St. Peter University Hospital, Rue Haute, 322, 1000, Brussels, Belgium. annick.delvigne@yucom.be
authors.forename: A
authors.initials: A
authors.lastname: Delvigne
authors.forename: C
authors.initials: C
authors.lastname: Carlier
authors.forename: S
authors.initials: S
authors.lastname: Rozenberg
mesh_terms: D000328:Adult; D004334:Drug Administration Schedule; D004958:Estradiol / Q000097:blood; D005240:Feasibility Studies; D005260:Female; D005307:Fertilization in Vitro; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors*; D006801:Humans; D008596:Menotropins / Q000008:administration & dosage* / Q000627:therapeutic use; D016471:Ovarian Hyperstimulation Syndrome / Q000517:prevention & control*; D011247:Pregnancy; D018873:Pregnancy Rate
chemical_list: D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D008596:Menotropins