title: Islands of linkage disequilibrium.
abstract: A detailed knowledge of patterns of linkage disequilibrium in human populations is widely seen as a prerequisite for effective population-based disease gene mapping. New data suggest that linkage disequilibrium is highly structured into discrete blocks of sequence separated by hot spots of recombination.
authors.forename: D B
authors.initials: DB
authors.lastname: Goldstein
mesh_terms: D016022:Case-Control Studies; D005826:Genetics, Medical; D006801:Humans; D015810:Linkage Disequilibrium; D011995:Recombination, Genetic