[Effect of amyxin--a domestic analog of tilorone--on characteristics of interferon and immune status of man].
The influence of amyxin, the Russian oral analog of tilorone, on the human interferon and immune status has been evaluated. As revealed by this investigation the administration of amyxin has produced a rise in the content of serum interferon, an increase in the capacity of leukocytes and lymphocytes for synthesizing alpha- and gamma-interferon, the activation of NK and phagocytizing cells of peripheral blood. No essential influence of amyxin on the amount of B and T lymphocytes, their subpopulations and the levels of the main classes of immunoglobulins has been established.
Sel'kova
E P
EP
Botkin City Clinical Hospital, Gamaleya Research Institute of Epidemiology and Microbiology, Ivanovsky Institute of Virology, Moscow, Russia.
Semenenko
T A
TA
Nosik
N N
NN
Iudina
T I
TI
Amarian
M P
MP
Lavrukhina
L A
LA
Pantiukhova
T N
TN
Tarasova
G Iu
GIu
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D006801:Humans; D007369:Interferon Inducers / Q000494:pharmacology*; D016898:Interferon-alpha / Q000097:blood; D007371:Interferon-gamma / Q000097:blood; D007694:Killer Cells, Natural / Q000187:drug effects; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000378:metabolism; D013601:T-Lymphocytes / Q000187:drug effects; D013994:Tilorone / Q000494:pharmacology*
D000276:Adjuvants, Immunologic; D007369:Interferon Inducers; D016898:Interferon-alpha; D007371:Interferon-gamma; D013994:Tilorone