[Specific aspects of hemostasis and lipid peroxidation in thrombocyte membranes during expedition and shift organization of labor].
The aim of the present study is to investigate dynamics of the hemostasis system and structural and functional state of thrombocyte membranes by the LPO and AOD parameters under the conditions of expedition and shift organization of labour of worker tripping from the West Siberia middle latitudes to the Far North. A trend to hypocoagulemia and increases in LPO and AOD reactions were characteristic of the type-1 (adaptive) reaction. The type-2 (hypotensive) reaction included a trend to hypercoagulemia, an increase in LPO and a decrease in AOD reactions in thrombocyte membranes as well as a hypertensive reaction during the whole shift period. The type-3 (asthenic) reaction was described by hypocoagulemia, an increase in the amount of LPO products with a simultaneous decrease in the AOD activity and asthenic sleep disturbance.
Agadzhanian
N A
NA
Fateeva
N M
NM
Ermakova
N V
NV
Kolpakov
V V
VV
D000328:Adult; D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D001792:Blood Platelets / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology*; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D012892:Sleep Deprivation; D014937:Work