Sleeve-related thrombosis: a new form of catheter-related thrombosis.
In a detailed study of central venous catheter-related sleeve and thrombosis in experimental animals, a new form of thrombosis was detected and termed sleeve-related thrombosis. A silastic catheter was placed in the jugular vein and the anterior vena cava of 22 rabbits and 54 rats. After intervals of 1, 3, 7 days, 2, 3, 4 weeks and 1, 2, 4, 6 months the veins were examined by light microscopy and by transmission electron microscopy. In about 50% of the rats a thrombus was observed at the end of the catheter sleeve. Consecutive cutting allowed the visualization of a transition from a sleeve via part of sleeve and part of thrombus to a pure thrombus. This thrombus was separated from the vein wall and could not be considered a mural thrombus. As the thrombus was only attached to the terminal part of the organized catheter sleeve we propose the name sleeve-related thrombosis.
Xiang
D Z
DZ
Centre for Experimental Surgery and Anaesthesiology, University Hospital, Catholic University, Louvain, Belgium.
Verbeken
E K
EK
Van Lommel
A T
AT
Stas
M
M
De Wever
I
I
D000818:Animals; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D006651:Histocytochemistry; D007601:Jugular Veins; D008854:Microscopy, Electron; D023421:Models, Animal; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D013927:Thrombosis / Q000209:etiology* / Q000473:pathology; D013997:Time Factors; D014684:Venae Cavae