Non-invasive distension of the small bowel for magnetic-resonance imaging.
Magnetic resonance enteroclysis is a promising technique that allows assessment of the small bowel but needs invasive nasoduodenal intubation. We propose a non-invasive distension method for magnetic-resonance imaging (MRI) in which ispaghula, dissolved in an aqueous solution with meglumine gadoterate taken orally over 4 h forms a viscous hydrogel within the intestinal lumen. MRI results from ten volunteers showed good luminal distension, constant signal homogeneity, optimum demarcation of the bowel content from surrounding tissues, and a low rate of artefacts. Our method permits non-invasive high quality MRI of the small bowel.
Patak
M A
MA
Froehlich
J M
JM
von Weymarn
C
C
Ritz
M A
MA
Zollikofer
C L
CL
Wentz
K
K
D000328:Adult; D002400:Cathartics / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis; D007421:Intestine, Small / Q000187:drug effects*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011620:Psyllium / Q000494:pharmacology*
D002400:Cathartics; D011620:Psyllium