title: Accidental detection of lupus anticoagulants in children.
abstract: During routine pre-operative evaluation, a 6-month-old infant and an 11-year-old girl were found to have prolonged activated partial thromboplastin time with positive lupus anticoagulants. Both children underwent successful cardiac surgery and had no thrombotic or bleeding complications. A literature search revealed that positive lupus anticoagulants can follow minor infections in otherwise asymptomatic children and are benign and self-limiting. A minority, however, can develop bleeding, thrombosis or an auto-immune disorder.
authors.affiliation: Departments of Child Health and Haematology, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman. gopalax@omantel.net.om
authors.forename: P
authors.initials: P
authors.lastname: Venugopalan
authors.forename: R
authors.initials: R
authors.lastname: Bushra
authors.forename: D
authors.initials: D
authors.lastname: Gravell
mesh_terms: D015415:Biomarkers / Q000097:blood; D006348:Cardiac Surgical Procedures; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D010314:Partial Thromboplastin Time; D011300:Preoperative Care
chemical_list: D015415:Biomarkers; D016682:Lupus Coagulation Inhibitor