title: Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction.
abstract: OBJECTIVE
  To evaluate the effect of supernumerary preovulatory follicular reduction as an approach to avoid multiple pregnancies in ovulation induction or superovulation cycles.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Tertiary referral center.
  
  
  METHODS
  In 26 cycles, 24 patients underwent ovulation induction or superovulation with either clomiphene citrate or hMG.
  
  
  METHODS
  Selective follicle aspiration was performed before hCG administration.
  
  
  METHODS
  Clinical pregnancy rate and numbers of multiple pregnancies.
  
  
  RESULTS
  A mean number of 4.5 follicles with a diameter > or =15 mm and a mean number of 4.5 follicles with a diameter < or =14 mm were observed before hCG administration. A mean number of 2.3 follicles with a diameter > or =15 mm and a mean number of 1.8 follicles with a diameter < or =14 mm were aspirated before the hCG administration. Seven singleton pregnancies (26.9% per cycle) ensued from the treatment.
  
  
  CONCLUSIONS
  Aspiration of supernumerary follicles after ovulation induction or superovulation seems to be a valid approach to avoid multiple pregnancies without affecting pregnancy rate.
authors.affiliation: Centre for Reproductive Medicine, Dutch-speaking Brussels Free University, Brussels, Belgium. lriaaoc@az.vub.ac.be
authors.forename: C
authors.initials: C
authors.lastname: Albano
authors.forename: P
authors.initials: P
authors.lastname: Platteau
authors.forename: D
authors.initials: D
authors.lastname: Nogueira
authors.forename: R
authors.initials: R
authors.lastname: Cortvrindt
authors.forename: J
authors.initials: J
authors.lastname: Smitz
authors.forename: P
authors.initials: P
authors.lastname: Devroey
mesh_terms: D000328:Adult; D005260:Female; D005498:Follicular Phase; D006801:Humans; D006080:Ovarian Follicle / Q000601:surgery*; D010062:Ovulation Induction / Q000009:adverse effects*; D011247:Pregnancy; D018873:Pregnancy Rate; D011272:Pregnancy, Multiple; D012189:Retrospective Studies; D013396:Suction