Anti-neutrophil cytoplasmic antibodies in echinococcus granulosus hydatid disease.
The authors studied the presence of ANCA, evaluated by indirect immunofluorescence (IIF) and ELISA for anti-lactoferrin (LF), and anti-myeloperoxidase antibodies (anti-MPO), in sera of 69 patients with cystic echinococcosis (CE). According to Caremani's classification, 27 patients were considered to have active cysts and 42 patients were considered to have inactive cysts. ANCA were detected in 9 out of 27 patients (33.3%) with active cysts and in 3 out of 42 patients (7.1%) with inactive cysts. Differences between the two groups were statistically significant (P < 0.05). Anti-LF antibodies were found in seven patients (10.14%) and anti-MPO antibodies in ten patients (14.5%).
De Rosa
F G
FG
Department of Infectious Diseases, University of Turin, Ospedale Amedeo di Savoia, Corso Svizzera 164, 10149, Turin, Italy.
Amoroso
A
A
Teggi
A
A
Paparo
S B
SB
Franchi
C
C
Ferri
G M
GM
Caccavo
D
D
Afeltra
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000096:biosynthesis / Q000097:blood*; D001323:Autoantibodies / Q000097:blood; D002648:Child; D002675:Child, Preschool; D004443:Echinococcosis / Q000276:immunology*; D004444:Echinococcosis, Hepatic / Q000276:immunology; D004445:Echinococcosis, Pulmonary / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007781:Lactoferrin / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009195:Peroxidase / Q000276:immunology
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D009195:Peroxidase; D007781:Lactoferrin