[New strategy on medical research after completion of genome sequencing].
Real advances in biotechnology made it possible to complete human whole genome sequencing within a short duration. Although the genome includes a huge amount of information about biological functions and the interest is now directed to the study using genomic information, the genomic strategy is not clearly understood. The following 4 studies were therefore presented and discussed about the strategy after the completion of the genomic sequence in the 74th Annual Meeting of Japanese Pharmacological Society: 1) Asthma and atopic dermatitis: models for genetic and genomic investigations of complex genetic diseases, by W.C.O. Cookson (University of Oxford, Asthma Genetics Group, Wellcome Trust Centre for Human Genetics); 2) Molecular classification by global gene expression profiling: application on oncogenomic research, by H. Aburatani (Genome Science Division, Research Center for Advanced Science and Technology, University of Tokyo); 3) Functional genomic search of disease-related genes using microarrays with normalized rat cDNA library, by G. Tsujimoto, et al. (Department of Molecular, Cell Pharmacology, National Children's Medical Research Center: and 4) Acute ischemic change of mRNA expression in the hippocampus by GeneChip array analysis: a starting point for post-genome strategy, by S. Asai, et al.
Ishikawa
K
K
Department of Pharmacology, Nihon University School of Medicine, Tokyo 173-8610, Japan. ishikawa@med.nihon-u.ac.jp
Tsujimoto
G
G
D000818:Animals; D019295:Computational Biology; D020869:Gene Expression Profiling; D015723:Gene Library; D015894:Genome, Human; D023281:Genomics; D005838:Genotype; D006801:Humans; D010641:Phenotype; D017422:Sequence Analysis, DNA