title: Mizoroki-Heck type reaction of organoboron reagents with alkenes and alkynes. A Pd(II)-catalyzed pathway with Cu(OAc)2 as an oxidant.
abstract: [reaction: see text]. In contrast to the Pd(0)-catalyzed mechanism by Uemura, Mizoroki-Heck type reaction of boronic acids is found to proceed under a Pd(II)-mediated pathway using a catalytic amount of Pd(OAc)2 in the presence of Cu(OAc)2 as an oxidant. Treatment of a variety of alkenes with boronic acids, boronates, and sodium tetraphenylborate furnishes beta-arylated and alkenylated products in good to excellent yields. The reactions with norbornene, norbornadiene, and diphenylacetylene are also performed to give 1:2 or 2:1 coupling products.
authors.affiliation: Chemical Resources Laboratory, Tokyo Institute of Technology, Nagatsuta, Yokohama, Japan.
authors.forename: X
authors.initials: X
authors.lastname: Du
authors.forename: M
authors.initials: M
authors.lastname: Suguro
authors.forename: K
authors.initials: K
authors.lastname: Hirabayashi
authors.forename: A
authors.initials: A
authors.lastname: Mori
authors.forename: T
authors.initials: T
authors.lastname: Nishikata
authors.forename: N
authors.initials: N
authors.lastname: Hagiwara
authors.forename: K
authors.initials: K
authors.lastname: Kawata
authors.forename: T
authors.initials: T
authors.lastname: Okeda
authors.forename: H F
authors.initials: HF
authors.lastname: Wang
authors.forename: K
authors.initials: K
authors.lastname: Fugami
authors.forename: M
authors.initials: M
authors.lastname: Kosugi