Enantioselective synthesis of ancepsenolide and its analogs.
Ancepsenolide (1a-s) and the enantiomer (1a-r) were respectively synthesized from (S)- and (R)-2-[(R)-O-MEM-mandeloyloxylpropanal (3a-s and 3a-r) and diisopropyl hexadecanedioate (5). The analogs (1b, 2a and 2b) were synthesized by a similar method.
Takai
K
K
Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Kamiina, Nagano, Japan.
Iriye
R
R
D015107:4-Butyrolactone / Q000031:analogs & derivatives; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism
D005663:Furans; D007202:Indicators and Reagents; C004511:butenolide; D015107:4-Butyrolactone