Meningioma metastatic to thyroid gland.
OBJECTIVE
To describe the first reported case of meningioma metastasizing to and completely infiltrating the thyroid gland.


METHODS
We present a detailed case report, including radiographic, histologic, and immunostaining findings, in a patient with an atypical meningioma who had a progressively enlarging thyroid mass that proved to be a metastatic meningioma.


RESULTS
A 49-year-old man had a meningioma in the parieto-occipital region that had spread locally to the scalp and bone by the time of surgical resection. Local recurrence during the following year prompted repeated surgical resection, tumor embolization, radiotherapy, and chemotherapy. Despite aggressive therapy, the tumor progressed. A thyroid mass was first noted 2 years after the meningioma was diagnosed. Enlargement of the mass caused airway obstruction, necessitating an emergency thyroidectomy. Histologic examination of the thyroidectomy specimen showed that the thyroid gland had been extensively replaced by metastatic meningioma.


CONCLUSIONS
To our knowledge, this is the first reported case of metastatic meningioma extensively infiltrating the thyroid gland. This case report expands the spectrum of tumors that metastasize to the thyroid gland.
Hasan
R
R
Department of Medicine, Division of Endocrinology and Metabolism, New York Medical College and Westchester Medical Center, Valhalla, NY 10595.
Marshall
M C
MC
Medhi
M
M
Arshad
A
A
Braun
A
A
Panageas
E
E
D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008579:Meningioma / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011878:Radiotherapy; D012086:Reoperation; D013964:Thyroid Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D013965:Thyroidectomy; D014057:Tomography, X-Ray Computed
D000970:Antineoplastic Agents