Optimization of left ventricular function with carvedilol before high-risk cardiac surgery.
Patients with severe left ventricular dysfunction and symptomatic heart failure caused by ischemic or valvular heart disease face a high morbidity and mortality risk from cardiac surgery. We present data showing that excellent surgical outcome can be achieved after pre-treatment of such patients with carvedilol.
Kotlyar
E
E
Cardiopulmonary Transplant Unit, St. Vincent's Hospital, Sydney, New South Wales, Australia.
Macdonald
P S
PS
Keogh
A M
AM
Arnold
R H
RH
McCaffrey
D J
DJ
Wilson
M K
MK
Spratt
P M
PM
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002227:Carbazoles / Q000627:therapeutic use*; D006348:Cardiac Surgical Procedures / Q000379:methods*; D000077261:Carvedilol; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000627:therapeutic use*; D012307:Risk Factors; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use; D016277:Ventricular Function, Left / Q000187:drug effects*
D000959:Antihypertensive Agents; D002227:Carbazoles; D011412:Propanolamines; D014665:Vasodilator Agents; D000077261:Carvedilol