title: [Change in refraction and topography after penetrating keratoplasty suture removal].
abstract: OBJECTIVE
  To study the refractive and topographic modifications induced by penetrating keratoplasty suture removal.
  
  
  METHODS
  We prospectively studied 80 corneas from 80 patients who had undergone penetrating keratoplasty. All of the eyes were examined before and after all sutures were removed, respectively at 10.9 5.1 months and 21.5 9.6 months after keratoplasty. Subjective refraction, best spectacle-corrected visual acuity (LogMAR units), keratometry, and corneal topography using the EyeSys 2000((R)) device (axial tangential and refractive power) were recorded. Topographies were classified according to the pattern (Bogan classification) and the asphericity shape (prolate and oblate).
  
  
  RESULTS
  Best spectacle-corrected visual acuity (Log MAR units) increased significantly after suture removal (1.1 1.9 lines, plt; 0.001). Suture removal decreased the subjective cylinder (5.01 D 2.06 with suture, 4.11 2.08 without suture; p=0.009). The change in subjective cylinder correlated with the change in topographic pattern(s)=0.67 p<0.001). Conversely to the "bow tie" patterns, the other topographic patterns were more frequent after suture removal. The change in visual acuity was essentially explained by the change in subjective cylinder(s)=0.40 p=0.002). The average central corneal power decreased significantly after suture removal by 0.83 to 1.81 D (p<0.001), whereas the subjective spherical equivalent increased (hyperopization) (-4.07D 3.73 with suture, -3.48 3.40 without suture; p=0.02). The change in central corneal power significantly correlated with the change in subjective spherical equivalent (r(s)()>0.30 plt; 0.001). The corneal power of the mid-periphery did not significantly change after suture removal. Suture removal significantly modified the asphericity shape distribution. (majority of prolate shape with suture, majority of oblate shape without suture, p<0.001).
  
  
  CONCLUSIONS
  Keratoplasty sutures induce a central bulge in the corneal graft. Suture removal induces a decrease in the subjective cylinder and it increases the subjective spherical equivalent (hyperopization) through a decrease in the central corneal power. Suture removal modifies the corneal topographic pattern and shape. Visual acuity improvement after suture removal is mainly explained by the decrease in subjective astigmatism.
authors.affiliation: Pôle Saint Antoine/CHNO des Quinze -Vingts, Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Touzeau
authors.forename: S
authors.initials: S
authors.lastname: Scheer
authors.forename: V
authors.initials: V
authors.lastname: Borderie
authors.forename: C
authors.initials: C
authors.lastname: Allouch
authors.forename: T
authors.initials: T
authors.lastname: Bourcier
authors.forename: M
authors.initials: M
authors.lastname: Moldovan
authors.forename: L
authors.initials: L
authors.lastname: Laroche
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D019781:Corneal Topography; D005260:Female; D006801:Humans; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011446:Prospective Studies; D012029:Refraction, Ocular; D013537:Sutures