title: Pierre Robin sequence: a series of 117 consecutive cases.
abstract: A series of 117 cases of Pierre Robin Sequence are classified as isolated (48%), syndromic (35%), and with associated anomalies (17%); the latter group had a poor long-term prognosis. In isolated Pierre Robin Sequence, familial cases and a high incidence of twins were noted. Among syndromic Pierre Robin Sequence, 4 syndromes represent more than 50% of the diagnoses.
authors.affiliation: Department of Genetics, Necker Enfants-Malades Hospital, Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Holder-Espinasse
authors.forename: V
authors.initials: V
authors.lastname: Abadie
authors.forename: V
authors.initials: V
authors.lastname: Cormier-Daire
authors.forename: C
authors.initials: C
authors.lastname: Beyler
authors.forename: Y
authors.initials: Y
authors.lastname: Manach
authors.forename: A
authors.initials: A
authors.lastname: Munnich
authors.forename: S
authors.initials: S
authors.lastname: Lyonnet
authors.forename: G
authors.initials: G
authors.lastname: Couly
authors.forename: J
authors.initials: J
authors.lastname: Amiel
mesh_terms: D002675:Child, Preschool; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D010375:Pedigree; D010855:Pierre Robin Syndrome / Q000175:diagnosis* / Q000235:genetics* / Q000401:mortality; D011379:Prognosis; D015996:Survival Rate