Ovarian Sertoli-Leydig cell tumor: success with salvage therapy.
A case of metastatic ovarian Sertoli-Leydig cell tumor is presented. The patient achieved a complete pathologic response with four courses of cisplatin, vinblastine and bleomycin chemotherapy. Recurrence of the tumor was detected with elevated serum alpha-fetoprotein. After surgical debulking, the recurrence was treated with intra-arterial cisplatin and intravenous etoposide with pelvic radiation therapy followed by intravenous doxorubicin and cyclophosphamide. The patient is alive and disease free 75 months after initial diagnosis, 4 years after salvage therapy.
Finan
M.A.
MA
Division of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, FloridaDivision of Medicine, M.D. Anderson Hospital and Tumor Institute, Houston, Texas, USA.
Roberts
W.S.
WS
Kavanagh
J.J.
JJ