title: Multilesional primary cutaneous diffuse large B-cell lymphoma responsive to antibiotic treatment.
abstract: Borrelia burgdorferi infection has been implicated in cutaneous B-cell lymphoma. We report a case of multilesional primary cutaneous large B-cell lymphoma without extracutaneous spread in a patient with elevated B. burgdorferi titers. After antibiotic therapy, clinical remission and a subsequent drop in B. burgdorferi antibody titers were obtained.
authors.affiliation: Department of Dermatology, University Hospital, Zürich, Switzerland.
authors.forename: G F
authors.initials: GF
authors.lastname: Hofbauer
authors.forename: B
authors.initials: B
authors.lastname: Kessler
authors.forename: W
authors.initials: W
authors.lastname: Kempf
authors.forename: F O
authors.initials: FO
authors.lastname: Nestle
authors.forename: G
authors.initials: G
authors.lastname: Burg
authors.forename: R
authors.initials: R
authors.lastname: Dummer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D025065:Borrelia burgdorferi / Q000276:immunology; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000097:blood / Q000276:immunology / Q000517:prevention & control; D016393:Lymphoma, B-Cell / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D012074:Remission Induction; D012867:Skin / Q000187:drug effects / Q000473:pathology; D012878:Skin Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline