title: Seroepidemiological study of Helicobacter pylori infection in asymptomatic people in South Korea.
abstract: BACKGROUND
  Helicobacter pylori infection occurs throughout the world and causes gastroduodenal diseases in all age groups. The prevalence of H. pylori infection varies between countries and races. The aim of this study was to evaluate the seroprevalence of H. pylori infection in asymptomatic healthy people in South Korea.
  
  
  METHODS
  From March 1998 to October 1998, 5732 asymptomatic subjects who responded to the self-assessment questionnaires from 54 hospitals in South Korea were enrolled in this study. The serum levels of antibodies for H. pylori immunoglobulinG were measured by using an ELISA test.
  
  
  RESULTS
  The overall seroprevalence of H. pylori infection was 46.6% and there was no statistical difference between males (47.2%) and females (45.9%). In adults, a significant difference was observed between genders. According to the geographic areas, the high prevalent provinces were Kangwon (53.4%), Cheju (52.9%) and Cholla province (50.6%); Seoul (41.9%) was the lowest prevalent area. The seroprevalence increased with age and was highest when patients were aged in their 40s (78.5%). The characteristic feature of our study was that the infection rate was steeply increased in three age groups (10-12 year olds, 16-19 year olds and those aged in their 20s). In Seoul, there was no difference in the prevalence rate among the districts studied.
  
  
  CONCLUSIONS
  This nation-wide seroprevalence of H. pylori infection in South Korea was 46.6%, which showed the transition from a developing country to a developed country. More studies on the epidemiological factors and the route of transmission of H. pylori infection should be warranted.
authors.affiliation: Kangdong Sacred Heart Hospital, Seoul, Korea. bacter@www.hallym.or.jp
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: H Y
authors.initials: HY
authors.lastname: Kim
authors.forename: N Y
authors.initials: NY
authors.lastname: Kim
authors.forename: S W
authors.initials: SW
authors.lastname: Kim
authors.forename: J G
authors.initials: JG
authors.lastname: Kim
authors.forename: J J
authors.initials: JJ
authors.lastname: Kim
authors.forename: I H
authors.initials: IH
authors.lastname: Roe
authors.forename: J K
authors.initials: JK
authors.lastname: Seo
authors.forename: J G
authors.initials: JG
authors.lastname: Sim
authors.forename: H
authors.initials: H
authors.lastname: Ahn
authors.forename: B C
authors.initials: BC
authors.lastname: Yoon
authors.forename: S W
authors.initials: SW
authors.lastname: Lee
authors.forename: Y C
authors.initials: YC
authors.lastname: Lee
authors.forename: I S
authors.initials: IS
authors.lastname: Chung
authors.forename: H Y
authors.initials: HY
authors.lastname: Jung
authors.forename: W S
authors.initials: WS
authors.lastname: Hong
authors.forename: K W
authors.initials: KW
authors.lastname: Choi
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D016481:Helicobacter Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D016480:Helicobacter pylori / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007223:Infant; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D016036:Seroepidemiologic Studies
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G