title: An atypical neuropsychological profile of a Korsakoff syndrome patient throughout the follow-up.
abstract: The basis of amnesia in alcoholic Wernicke-Korsakoff syndrome (WKS) has been generally associated with diencephalic lesions and more specifically with lesions of the anterior thalamic nuclei. These brain structures are considered to be involved in encoding/consolidation processes of episodic memory. However, frontal lobe damage responsible for executive function deficits has also been documented. The present report details the nature and extent of amnesia in an alcoholic patients with WKS and which appears to be mainly due to frontal lobe (executive) deficits.
authors.affiliation: Department of Psychiatry, Free University of Brussels, Brugmann Hospital, Brussels, Belgium. xnoel@ulb.ac.be
authors.forename: X
authors.initials: X
authors.lastname: Noël
authors.forename: N
authors.initials: N
authors.lastname: Schmidt
authors.forename: M
authors.initials: M
authors.lastname: Van der Linden
authors.forename: R
authors.initials: R
authors.lastname: Sferrazza
authors.forename: C
authors.initials: C
authors.lastname: Hanak
authors.forename: J
authors.initials: J
authors.lastname: De Mol
authors.forename: C
authors.initials: C
authors.lastname: Kornreich
authors.forename: I
authors.initials: I
authors.lastname: Pelc
authors.forename: P
authors.initials: P
authors.lastname: Verbanck
mesh_terms: D000425:Alcohol Amnestic Disorder / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D020643:Anterior Thalamic Nuclei / Q000473:pathology / Q000503:physiopathology; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D020915:Korsakoff Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D008297:Male; D011939:Mental Recall / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D012153:Retention, Psychology / Q000502:physiology; D014899:Wernicke Encephalopathy / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology