[Amniocentesis and chorionic villi biopsy. A 10-year material].
OBJECTIVE
The aim of the study was to evaluate the prenatal diagnosis at a secondary referral hospital.


METHODS
A retrospective study was carried out on 1752 women examined by amniocentesis (AC) (n = 1037) or chorion villus sampling (CVS) (n = 715) at Randers Centralsygehus from 1 April 1987 to 31 December 1996.


RESULTS
A cytogenetic diagnosis was made in 99.8% of the AC group and 99.4% of the CVS group. Complications, recorded as either spontaneous abortion, bleeding/threatening abortion, pain/contractions or amniotic fluid leakage, were seen in 1.9%, 3.3%, 2.9%, and 2.3% after AC and 1.8%, 7.3%, 3.4%, and 0% after CVS. There were significantly more re-examinations after CVS when the procedure was carried out by less experienced operators (p < 0.003), whereas experience did not influence the number of re-examinations after AC (p = 0.8).


CONCLUSIONS
The frequency of complications during prenatal procedures performed over a period of ten years was comparable with that reported in other studies. It is expedient and safe to perform prenatal examinations at a secondary referral hospital where currently 200 procedures are performed each year.
Ejskjaer
K V
KV
Randers Centralsygehus, gynaekologisk obstetrisk afdeling. k.ejskjaer@dadlnet.dk
Sørensen
A U
AU
Johannesen
P L
PL
Praest
J
J
D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects / Q000706:statistics & numerical data; D015193:Chorionic Villi Sampling / Q000009:adverse effects / Q000706:statistics & numerical data; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D003718:Denmark; D005260:Female; D030342:Genetic Diseases, Inborn / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D006801:Humans; D008423:Maternal Age; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000473:pathology; D018566:Pregnancy, High-Risk; D012189:Retrospective Studies