title: Difficulties using the Franco-Italian Glossary in assessing toxicity of cervical cancer treatment.
abstract: Shakespeare TP, Ferrier AJ, Holecek MJ, Jagavkar RS, Stevens MJ. Difficulties using the Franco-Italian Glossary in assessing toxicity of cervical cancer treatment. Int J Gynecol Cancer 1998; 8: 51-55 We assessed the toxicities of patients treated for cervical cancer using the revised Franco-Italian Glossary (FIG). A total of 69 separate complications were appraised in 47 patients; however, only 43.5% of these side-effects could be accurately graded. In all, 56.5% of toxicities could not be scored for a variety of reasons: (1) the FIG does not account for all possible complications of cervical cancer treatment; (2) some important toxicities are regarded as too minor to be graded; (3) subjective assessment of some side-effects did not allow consensus to be reached when assigning a grade; (4) we could not accurately score toxicities using the FIG in a retrospective manner. Previous studies utilizing the FIG retrospectively have noted few problems with its use, with no indication of the number of toxicities unable to be graded. In view of the inability to grade the majority of complications in the present study in an accurate manner, we conclude that the revised FIG requires detailed data that are best collected prospectively and that several minor modifications of the glossary should be considered. Results of studies using the glossary retrospectively should be viewed with caution.
authors.affiliation: Department of Radiation Oncology; Department of Obstetrics and Gynaecology, The Royal North Shore Hospital of Sydney, St. Leonards, New South Wales, Australia.
authors.forename: T. P.
authors.initials: TP
authors.lastname: Shakespeare
authors.forename: A. J.
authors.initials: AJ
authors.lastname: Ferrier
authors.forename: M. J.
authors.initials: MJ
authors.lastname: Holecek
authors.forename: R. S.
authors.initials: RS
authors.lastname: Jagavkar
authors.forename: M. J.
authors.initials: MJ
authors.lastname: Steven