title: Risk factors and outcome in 100 patients with aneurysmal subarachnoid hemorrhage.
abstract: OBJECTIVE
  Clinical and surgical outcome of patients with subarachnoid hemorrhage (SAH) due to ruptured aneurysm were assessed in comparison to pre-operative data and risk factors such as previous medical history, clinical presenting condition, CT findings and site of bleeding.
  
  
  METHODS
  We evaluated 100 consecutive patients with aneurysmal SAH. Gender, color, history of hypertension, smoking habit, site and size of aneurysm, admittance and before surgery Hunt Hess scale, need for cerebro-spinal fluid shunt, presence of complications during the surgical procedure, Glasgow Outcome Scale, presence of vasospasm and of rebleeding were assessed and these data matched to outcome. For statistical analysis, we applied the chi-squared test or Fisher's test using the pondered kappa coefficient. Kruskal-Wallis test was used for comparison of continue variables. Tendency of proportion was analyzed through Cochran-Armitage test. Significance level adopted was 5%.
  
  
  RESULTS
  Patients studied were mainly white, female, without previous history of hypertension and non-smokers. Upon hospital admittance, grade 2 of Hunt-Hess scale was most frequently observed (34%), while grade 3 of Fisher scale was the most prevalent. Single aneurysms were most frequent at anterior circulation, between 12 and 24 mm. The most frequent Glasgow Outcome Scale observed was 5 (60%). Hunt Hess upon the moment of surgery and presence of complications during surgical procedure showed positive correlation with clinical outcome (p=0.00002 and p=0.001, respectively). Other variables were not significantly correlated to prognosis. Tendency of proportion was observed between Hunt-Hess scale and Fisher scale.
  
  
  CONCLUSIONS
  Among variables such as epidemiological data, previous medical history and presenting conditions of patients with ruptured aneurysms, the Hunt-Hess scale upon the moment of surgery and the presence of surgical adversities are statistically related to degree of disability.
authors.affiliation: Division of Neurosurgery, Department of Neurology, Faculty of Medical Sciences, State University of Campinas, Campinas, SP, Brazil.
authors.forename: L
authors.initials: L
authors.lastname: Bonilha
authors.forename: E L
authors.initials: EL
authors.lastname: Marques
authors.forename: E F
authors.initials: EF
authors.lastname: Carelli
authors.forename: Y B
authors.initials: YB
authors.lastname: Fernandes
authors.forename: A C
authors.initials: AC
authors.lastname: Cardoso
authors.forename: M V
authors.initials: MV
authors.lastname: Maldaum
authors.forename: G
authors.initials: G
authors.lastname: Borges
mesh_terms: D001938:Brazil / Q000453:epidemiology; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D002532:Intracranial Aneurysm / Q000453:epidemiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011300:Preoperative Care; D011446:Prospective Studies; D012307:Risk Factors; D018709:Statistics, Nonparametric; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology / Q000601:surgery*; D016896:Treatment Outcome