title: [Indications for splenectomy in the surgical treatment of gastric cancer].
abstract: The extent of lymphadenectomy in the treatment of gastric cancer is still a matter of debate. Splenectomy, which has to be performed using the common surgical techniques to remove the lymph nodes of the splenic hilus, is part of this problem. The indications for splenectomy in the treatment of gastric cancer are examined, considering the results in terms of operative mortality and morbidity and long term survival. The Authors analyze a consecutive series of 129 patients who underwent total gastrectomy with D2 or D3 lymphadenectomy for gastric cancer. Forty-seven splenectomies were performed among 79 patients submitted to total gastrectomy. Splenectomy did not influence the perioperative mortality. Morbidity was higher in the patients who underwent splenectomy (33.3%) than in the patients without splenectomy (28.12%). This difference was not statistically significant. Five-year survival was higher in the group that did not undergo splenectomy (37.6% vs 27%) without any significant difference. Also considering the results in literature, splenectomy is associated with an increase in morbidity, and, for some authors, also in mortality, without any significant improvement in long-term survival. The indication for splenectomy in gastric cancer is based on an accurate evaluation of the localization and the depth of the parietal infiltration of the tumor.
authors.affiliation: U.C.O. di Clinica Chirurgica Generale e Terapia Chirurgica, Dipartimento Universitario Clinico di Scienze Chirurgiche Generali, Anestesiologiche e Medicina Intensiva, Scuola di Specializzazione in Chirurgia Generale, Università degli Studi di Trieste.
authors.forename: M
authors.initials: M
authors.lastname: Bortul
authors.forename: G
authors.initials: G
authors.lastname: Guarino
authors.forename: L
authors.initials: L
authors.lastname: Calligaris
authors.forename: M
authors.initials: M
authors.lastname: Roseano
mesh_terms: D000368:Aged; D006801:Humans; D011183:Postoperative Complications / Q000453:epidemiology; D013156:Splenectomy / Q000009:adverse effects; D013274:Stomach Neoplasms / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate