title: Inhibition of marine bacteria by extracts of macroalgae: potential use for environmentally friendly antifouling paints.
abstract: Although a total ban on the use of TBT coatings is not expected in the short term, there is a growing need for environmentally safe antifouling systems. A search for new non-toxic antifoulants has been carried out among marine macroalgae. Antifouling activity of aqueous, ethanolic and dichloromethane extracts from 30 marine algae from Brittany coast (France) was examined in vitro against 35 isolates of marine bacteria. About 20% of the extracts were found to be active. The high levels of inhibitory activities against bacteria recorded in some extracts and the absence of toxicity on the development of oyster and sea urchin larvae and to mouse fibroblast growth suggests a potential for novel active ingredients in antifouling preparations.
authors.affiliation: FRE2125 CNRS-MNHN-UBO, Station de Biologie Marine, Muséum National d'Histoire Naturelle-Collége de France, Concarneau. claire_hellio@hotmail.com
authors.forename: C
authors.initials: C
authors.lastname: Hellio
authors.forename: D
authors.initials: D
authors.lastname: De La Broise
authors.forename: L
authors.initials: L
authors.lastname: Dufossé
authors.forename: Y
authors.initials: Y
authors.lastname: Le Gal
authors.forename: N
authors.initials: N
authors.lastname: Bourgougnon
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D018441:Biofilms / Q000187:drug effects*; D056890:Eukaryota / Q000378:metabolism*; D007814:Larva; D008386:Marine Biology; D010125:Ostreidae / Q000187:drug effects / Q000254:growth & development; D010150:Paint / Q000633:toxicity*; D012617:Sea Urchins / Q000187:drug effects / Q000254:growth & development; D014871:Water Microbiology
chemical_list: D000900:Anti-Bacterial Agents