[Structural-functional characteristics of the air-blood barrier of lungs upon inhalation of low concentrations of lead salt].
Under realization of electronmicroscopic investigation of respiratory department of lungs is shown, that in conditions of influence of low concentration of lead salts on the initial stages both intracellular, and ancellular processes caused stress influence on lungs and underlie the unspecific mechanism of lead action of lead had activated. The further influence of heavy metal results in adaptation of all systems to new conditions of functioning and is qualitatively new condition of a higher structurally functional level. On late stages accumulation of lead in lungs and its injuring action the picture of toxical alveolitis with the subsequent activation of collagen formation and development of interstitial fibrosis followed develops.
Kotsariev
O S
OS
Ukrainian State Research Institute of Medical and Social Problems of Physical Inability, Dniepropetrovsk.
Antoniuk
S V
SV
Lykholat
O A
OA
D000280:Administration, Inhalation; D000818:Animals; D015824:Blood-Air Barrier / Q000187:drug effects*; D005260:Female; D007854:Lead / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000633:toxicity*; D008168:Lung / Q000473:pathology*; D008297:Male; D011650:Pulmonary Alveoli / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000473:pathology; D051381:Rats
D007854:Lead