Accidental detection of lupus anticoagulants in children.
During routine pre-operative evaluation, a 6-month-old infant and an 11-year-old girl were found to have prolonged activated partial thromboplastin time with positive lupus anticoagulants. Both children underwent successful cardiac surgery and had no thrombotic or bleeding complications. A literature search revealed that positive lupus anticoagulants can follow minor infections in otherwise asymptomatic children and are benign and self-limiting. A minority, however, can develop bleeding, thrombosis or an auto-immune disorder.
Venugopalan
P
P
Departments of Child Health and Haematology, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman. gopalax@omantel.net.om
Bushra
R
R
Gravell
D
D
D015415:Biomarkers / Q000097:blood; D006348:Cardiac Surgical Procedures; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D010314:Partial Thromboplastin Time; D011300:Preoperative Care
D015415:Biomarkers; D016682:Lupus Coagulation Inhibitor