title: Functional outcomes and quality of life in patients with brain tumours: a review of the literature.
abstract: OBJECTIVE
  To review the literature with respect to functional outcomes and quality of life as it pertains to individuals with brain tumours.
  
  
  RESULTS
  Most functional outcome papers have focused on acute inpatient rehabilitation. In general, patients with brain tumours have comparable rates of functional gains as other models of neurologic disability. Tumour type and concomitant treatment do not impact functional outcome. Functional independence may predict survivability in certain populations. Numerous instruments are used to measure the multiple facets of quality of life. Depression, anger and fatigue can impact both physical and psychological aspects of quality of life. The physical and functional aspects can vary depending on the tumour type. Treatment regimens can negatively impact quality of life.
  
  
  CONCLUSIONS
  Brain tumour patients experience changes in function and quality of life during their disease course. Rehabilitation services may offer a unique opportunity to influence both functional outcome and more closely assess quality of life in these individuals.
authors.affiliation: Rehabilitation and Research Center, Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, Medical College of Virginia Hospitals, Richmond, VA 23298, USA.mehuang@hsc.vcu.edu
authors.forename: M E
authors.initials: ME
authors.lastname: Huang
authors.forename: J
authors.initials: J
authors.lastname: Wartella
authors.forename: J
authors.initials: J
authors.lastname: Kreutzer
authors.forename: W
authors.initials: W
authors.lastname: Broaddus
authors.forename: L
authors.initials: L
authors.lastname: Lyckholm
mesh_terms: D001932:Brain Neoplasms / Q000523:psychology* / Q000534:rehabilitation*; D006801:Humans; D017063:Outcome Assessment, Health Care; D011788:Quality of Life / Q000523:psychology; D020127:Recovery of Function