The mechanism of action of DNA photolyases.
Structural analysis, biochemistry and model studies have provided new insights into the mechanism of action of photolyases. The light-driven electron and energy transfer events that lead to the photolyase-catalyzed repair of lethal, mutagenic and carcinogenic UV-light-induced DNA lesions have all been examined in the past few years.
Carell
T
T
Philipps-University Marburg, Department of Chemistry, Hans-Meerwein-Street, D-35032 Marburg, Germany. carell@mailer.uni-marburg.de
Burgdorf
L T
LT
Kundu
L M
LM
Cichon
M
M
D002273:Carcinogens; D002384:Catalysis; D004247:DNA / Q000378:metabolism; D004249:DNA Damage / Q000528:radiation effects; D004260:DNA Repair; D004255:Deoxyribodipyrimidine Photo-Lyase / Q000737:chemistry* / Q000502:physiology; D006801:Humans; D008027:Light; D015394:Molecular Structure; D009154:Mutation / Q000528:radiation effects; D010084:Oxidation-Reduction; D011740:Pyrimidine Dimers / Q000378:metabolism*; D013379:Substrate Specificity
D002273:Carcinogens; D011740:Pyrimidine Dimers; D004247:DNA; C098727:pyrimidine(6-4)pyrimidone photolyase; D004255:Deoxyribodipyrimidine Photo-Lyase