title: [Stimulatory effect of sodium deoxycholate on alpha-ergocryptine productivity of Claviceps purpurea 94002 (EKPN94002)].
abstract: The stimulation of sodium deoxycholate (SDC) on alpha-ergocryptine production of Claviceps purpurea strain 94002 (EKPN94002) was investigated. Preliminary results indicated that SDC, as a stimulator and at appropriate concentrations, could obviously increase the extracellular and the total production levels of the ergot alkaloid. Satisfied results were obtained when 6.0 mg.L-1 of SDC was present in the seed and fermentation media. The possible mechanism was discussed.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050.
authors.forename: P
authors.initials: P
authors.lastname: Zhu
authors.forename: H X
authors.initials: HX
authors.lastname: He
authors.forename: S Z
authors.initials: SZ
authors.lastname: Chen
mesh_terms: D002967:Claviceps / Q000378:metabolism*; D003840:Deoxycholic Acid / Q000494:pharmacology*; D004873:Ergolines / Q000378:metabolism*
chemical_list: D004873:Ergolines; D003840:Deoxycholic Acid; C100269:ergocryptine