title: Sentinel node staging of early breast cancer using lymphoscintigraphy and the intraoperative gamma detecting probe.
abstract: Lymphoscintigraphy combined with intraoperative gamma-probe detection of sentinel lymph nodes in patients with inoperable early primary breast cancers is effective for staging the disease. The clinical alternative is axillary lymph node dissection, which is a far more invasive procedure and is accompanied by significant morbidity. Accuracy of staging is enhanced by immunohistochemical staining of micrometastases, which pathologists can easily perform for one to three sentinel lymph nodes, but not for 20 to 30 nodes, using axillary dissection procedure. Optimum methodology is presented for performing sentinel lymph node imaging and is important for accurate identification of sentinel node(s).
authors.affiliation: Department of Radiology, Emory University School of Medicine, Veterans Affairs Medical Center, Atlanta, Georgia 30033, USA.
authors.forename: N P
authors.initials: NP
authors.lastname: Alazraki
authors.forename: T
authors.initials: T
authors.lastname: Styblo
authors.forename: S F
authors.initials: SF
authors.lastname: Grant
authors.forename: C
authors.initials: C
authors.lastname: Cohen
authors.forename: T
authors.initials: T
authors.lastname: Larsen
authors.forename: S
authors.initials: S
authors.lastname: Waldrop
authors.forename: J N
authors.initials: JN
authors.lastname: Aarsvold
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D021701:Sentinel Lymph Node Biopsy
chemical_list: D019275:Radiopharmaceuticals