GABAergic and NPY-Y(1) network in the medial amygdala: a neuroanatomical basis for their functional interaction.
We used Y(1)R/LacZ transgenic mice to investigate the interaction between NPY, GABA and Y(1) receptors in the amygdala. Immunolabeling of GABA and NPY positive neurons and histochemical staining of beta-galactosidase revealed NPY and GABA colocalization and close contacts of NPY-positive fibers with GABAergic neurons also expressing the Y(1)R/LacZ transgene.
Oberto
A
A
Sezione di Farmacologia, Dipartimento di Anatomia, Farmacologia e Medicina Legale, Università di Torino, Via Pietro Giuria 13, 10125, Torino, Italy.
Panzica
G C
GC
Altruda
F
F
Eva
C
C
D000679:Amygdala / Q000033:anatomy & histology* / Q000378:metabolism*; D000818:Animals; D015870:Gene Expression / Q000502:physiology; D008297:Male; D051379:Mice; D008822:Mice, Transgenic; D009415:Nerve Net / Q000378:metabolism; D009478:Neuropeptide Y / Q000378:metabolism / Q000502:physiology*; D018079:Receptors, GABA / Q000378:metabolism / Q000502:physiology*; D017476:Receptors, Neuropeptide Y / Q000378:metabolism / Q000502:physiology*
D009478:Neuropeptide Y; D018079:Receptors, GABA; D017476:Receptors, Neuropeptide Y; C097212:neuropeptide Y-Y1 receptor