[Cardiomyogenesis in Rana ridibunda tadpoles during metamorphosis in normal conditions and after exposure to various concentrations of cadmium ions].
During metamorphosis period Rana ridibunda ventricular cardiomyocytes possess strong ability to adapt to altering developmental conditions, certain peculiarities of differentiation were observed during this process, cell death and mitotic activity increases. The action of different concentrations of cadmium ions on Rana ridibunda larvae changes interrelation and intensity of basic processes of cardiac muscular histogenesis, leading to differentiation disorders, suppression of proliferative activity and intensification of cardiomyocytes death.
Rudenko
E Iu
EIu
Department of Histology and Embryology, State Medical University of Samara.
Iamshchikov
N V
NV
D000818:Animals; D002104:Cadmium / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000187:drug effects / Q000254:growth & development*; D007814:Larva; D008675:Metamorphosis, Biological; D011895:Rana ridibunda / Q000254:growth & development*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D014874:Water Pollutants, Chemical; D002104:Cadmium