title: A Merkel cell carcinoma of the skin.
abstract: A 79-year old female caucasian patient presented in January 91 with a nodular lesion of the right cheek that had appeared rapidly. The histologic specimen was in favour of a primary neuroendocrine skin tumor, Merkel cell carcinoma-. In March 91, a relapsing nodule had grown up and adenopathies were found on the right parotid and sub-mandibular spaces. An aggressive polychemotherapy was performed for 6 cycles and a complete remission was obtained. In November 91 the sub-mandibular lymph node had reappeared. A complete staging was again performed. After 3 cycles of chemotherapy, a regional radiotherapy completed the treatment. With a follow-up of more than 8 years the patient stays in complete remission in April 2000.
authors.affiliation: Department of Dermatology, Centre Hospitalier de Luxembourg 4, rue Barblé-L-1210 Luxembourg.
authors.forename: J
authors.initials: J
authors.lastname: Reiffers-Mettelock
authors.forename: F
authors.initials: F
authors.lastname: Ries
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015266:Carcinoma, Merkel Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008189:Luxembourg; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D044465:White People