title: Nickel-promoted alkylative or arylative carboxylation of alkynes.
abstract: [reaction: see text]. Nickel-promoted alkylative or arylative carboxylation of terminal alkynes via a carbon dioxide fixation process was investigated. In the presence of a stoichiometric amount of a zero-valent nickel complex, the reaction of alkynes with CO2 gave a nickelacycle, which was reacted with various organozinc reagents under very mild conditions to provide beta,beta'-disubstituted, alpha,beta-unsaturated carboxylic acids in a highly regio- and stereoselective manner.
authors.affiliation: Graduate School of Pharmaceutical Scieneces, Hokkaido University, Sapporo 060-0812, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Takimoto
authors.forename: K
authors.initials: K
authors.lastname: Shimizu
authors.forename: M
authors.initials: M
authors.lastname: Mori