Determination of paralytic shellfish poisoning toxins by high-performance ion-exchange chromatography.
An efficient LC method has been developed for the determination of paralytic shellfish poisoning (PSP) toxins based on ion-exchange chromatographic separation of the toxins followed by electrochemical post-column oxidation and fluorescence detection as well as mass spectrometric (MS) detection. The method can be applied to the determination of PSP toxins in phytoplankton and to control seafood for PSP content.
Jaim
E
E
Department of Food Chemistry, Institute of Nutrition, Friedrich-Schiller-University Jena, Germany. jaime@mampf.ieu.uni-jena.de
Hummert
C
C
Hess
P
P
Luckas
B
B
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D002852:Chromatography, Ion Exchange / Q000379:methods*; D004563:Electrochemistry; D009498:Neurotoxins / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D057096:Shellfish Poisoning; D013050:Spectrometry, Fluorescence
D009498:Neurotoxins