Spinal meningioma after treatment for Hodgkin disease. Case report.
Long-term survivors of Hodgkin disease may develop second primary tumors caused by the mutagenic effects of radio- and chemotherapy. The authors describe the case of a 35-year-old woman who presented with an unusual meningioma of the cervical spine 9 years after undergoing combined-modality treatment for Hodgkin disease. To the authors' knowledge, this is the first report of spinal meningioma as a complication of such therapy. Whereas radiation-induced intracranial meningiomas are well described in the literature, treatment-induced meningiomas of the spine have not been widely recognized.
Martin
A J
AJ
Department of Neurosurgery, King's College Hospital, London, United Kingdom. spkaajm@iop.kcl.ac.uk
Hammond
C J
CJ
Dobbs
H J
HJ
Al-Sarraj
S
S
Thomas
N W
NW
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D003131:Combined Modality Therapy / Q000009:adverse effects; D005260:Female; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D008579:Meningioma / Q000209:etiology*; D016609:Neoplasms, Second Primary; D011878:Radiotherapy / Q000009:adverse effects; D013125:Spinal Neoplasms / Q000209:etiology*