title: Choledochocholedochostomy conversion to hepaticojejunostomy due to biliary obstruction in liver transplantation.
abstract: Choledochocholedochostomy with tutor (CC-T) or without (CC) is the technique of choice for biliary reconstruction in orthotopic liver transplantation (OLT), however, its rate of complications is high and does not decrease significantly over the years. Biliary obstruction is the most frequent complication and surgical treatment frequently involves conversion to hepaticojejunostomy (H-J). Out of 412 patients (448 OLTs) analyzed retrospectively, 74 (18%) presented biliary complications and 25 (6%) required conversion to H-J because of biliary obstruction, generally due to anastomotic stenosis (17 patients, 68%). Sixteen out of the 25 presented after the first 3 months, and in two patients, stenosis was secondary to arterial thrombosis. Anastomotic stenosis was more frequent in the CC group than in the CC-T group (9.9% versus 2.6%, p < 0.05). Sixteen patients (64%) underwent percutaneous dilatations, but the response was only transitory. There were no postoperative deaths. At the follow-up, three (12%) of the 17 surviving patients presented episodes of cholangitis which required percutaneous dilatations (1), revision of the H-J (1), or conversion to hepaticojejunoduodenostomy (1). Mean survival of patients with H-J was 70.9%, and the actuarial survival rate was 68% at 5 years. This does not differ from the actuarial survival in our series of transplanted patients (65%). CC or CC-T (in selected cases) is an adequate biliary reconstruction for OLT, in spite of the fact that a small number of patients will require conversion to H-J. H-J is an excellent technique of rescue in cases of biliary obstruction that are not possible to resolve by percutaneous dilatations.
authors.affiliation: General and Digestive Surgery, Abdominal Organ Transplant, 12 de Octubre, University Hospital, Madrid, Spain. emorenog@hdoc.insalud.es
authors.forename: R
authors.initials: R
authors.lastname: Gómez
authors.forename: E
authors.initials: E
authors.lastname: Moreno
authors.forename: C
authors.initials: C
authors.lastname: Castellón
authors.forename: I
authors.initials: I
authors.lastname: González-Pinto
authors.forename: C
authors.initials: C
authors.lastname: Loinaz
authors.forename: I
authors.initials: I
authors.lastname: García
mesh_terms: D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical; D001652:Bile Ducts / Q000473:pathology*; D002404:Catheterization; D002768:Choledochostomy; D002779:Cholestasis / Q000601:surgery*; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies