title: Effect of tension-free vaginal tape procedure on urodynamic continence indices.
abstract: OBJECTIVE
  To assess the difference in measured urethral function before and after tension-free vaginal tape procedure (TVT).
  
  
  METHODS
  Women who underwent TVT for genuine stress incontinence with or without intrinsic sphincter deficiency completed this study. Multichannel urodynamic testing was performed preoperatively and 6 weeks postoperatively. Maximum urethral closure pressure and pressure transmission ratio were recorded. Valsalva leak point pressures were determined at 150 mL and at full bladder capacity. Resting and straining urethral angles were measured using the cotton swab technique. Subjects completed both the Incontinence Impact Questionnaire and Urodynamic Distress Inventory preoperatively and postoperatively.
  
  
  RESULTS
  Thirty-five consecutive women were studied. Twenty-three (65.7%) had a preoperative diagnosis of intrinsic sphincter deficiency as defined by maximum urethral closure pressure less than 20 cm H(2)O and/or Valsalva leak point pressure less than 60 cm H(2)O. Subjective and objective success rates were 91% and 83%, respectively. Subjects showed an 86.8% (95% CI 71.9%, 100.0%) improvement in their Incontinence Impact Questionnaire score and a 72.9% (95% CI 62.6%, 83.1%) improvement in their Urodynamic Distress Inventory score. The mean change in maximum urethral closure pressure was -1.3 cm H(2)O (95% CI -5.9, 3.3), whereas the pressure transmission ratio increased 15.7% (95% CI 5.0%, 26.3%). The mean decrease in straining urethral angle was 16.3 degrees (95% CI -23.9 degrees, -8.7 degrees ). Cured subjects demonstrating hypermobility preoperatively continued to do so postoperatively.
  
  
  CONCLUSIONS
  There was a significant increase in pressure transmission ratio, but not maximum urethral closure pressure, after TVT. These changes are similar to those reported after retropubic urethropexy and traditional sling procedures. The effectiveness of the TVT sling does not appear to depend on a clinically significant change in the straining urethral angle.
authors.affiliation: Division of Female Pelvic Medicine and Reconstructive Surgery, Methodist Hospital, Indiana University School of Medicine, Indianapolis, Indiana 46220, USA. nmutone@yahoo.com
authors.forename: N
authors.initials: N
authors.lastname: Mutone
authors.forename: M
authors.initials: M
authors.lastname: Mastropietro
authors.forename: E
authors.initials: E
authors.lastname: Brizendine
authors.forename: D
authors.initials: D
authors.lastname: Hale
mesh_terms: D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D011312:Pressure; D013526:Surgical Mesh; D011795:Surveys and Questionnaires; D014521:Urethra / Q000503:physiopathology*; D014550:Urinary Incontinence, Stress / Q000503:physiopathology* / Q000601:surgery*; D014563:Urodynamics; D014621:Vagina