[The aging of the brain: relationship of difference between left and right cerebral hemisphere potential and motor asymmetry of mice].
Difference between left and right cerebral hemisphere potential (mV) is biophysical reflection of brain asymmetry. Cymbate changes of constant potential run during the life in both hemisphere of brain of mice. Number turning on the right of 10 attempt in T maze is a quantitative criteria of functional motor asymmetry. Manifest right asymmetry of behavior of mice observe only from 12 to 17 month old. Ambylateral behavior is character to animals younger and older this period. Thus, as difference between left and right cerebral hemisphere potential both motor asymmetry have nonlinear change with age. Coefficient of correlation between this parameters equal -0.42 for young (3-7 month) mice, +0.53 for old (21-28 month) mice. But this coefficient is near zero for mice from 11 to 19 month old. Results of our research show, that quality change in brain run in middle age.
Solov'eva
A S
AS
N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4, Kosygina Str., Moscow 119991. soloviova@mtu-net.ru
Obukhova
L K
LK
D000367:Age Factors; D000375:Aging / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology*; D051379:Mice; D009048:Motor Skills / Q000502:physiology*