Prevention by lactic acid bacteria of the oxidation of human LDL.
Ether extracts of lactic acid bacteria were analyzed for prevention of the oxidation of erythrocyte membrane and human low-density lipoprotein in vivo. Streptococcus thermophilus 1131 and Lactobacillus delbrueckii subsp. bulgaricus 2038, yogurt starters, were chosen as test-strains, and ether extracts of these cultures were used as samples. Both strain 1131 and strain 2038 produced radical scavengers and inhibited oxidation of erythrocyte membranes and low-density lipoproteins. The antioxidative activity of strain 2038 was higher than that of strain 1131.
Terahara
M
M
Food Functionality Research Institute, Meiji Milk Products Co., Ltd., Higashimurayama, Tokyo, Japan.
Kurama
S
S
Takemoto
N
N
D000328:Adult; D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D002855:Chromatography, Thin Layer; D003300:Copper / Q000737:chemistry; D004910:Erythrocyte Membrane / Q000737:chemistry; D016166:Free Radical Scavengers; D006801:Humans; D066298:In Vitro Techniques; D019344:Lactic Acid / Q000378:metabolism*; D007778:Lactobacillus / Q000737:chemistry*; D008077:Lipoproteins, LDL / Q000737:chemistry*; D008297:Male; D010084:Oxidation-Reduction; D011817:Rabbits; D013291:Streptococcus / Q000737:chemistry*; D017392:Thiobarbituric Acid Reactive Substances / Q000737:chemistry
D000975:Antioxidants; D016166:Free Radical Scavengers; D008077:Lipoproteins, LDL; D017392:Thiobarbituric Acid Reactive Substances; D019344:Lactic Acid; D003300:Copper