title: A case of subungual reactive eccrine syringofibroadenoma.
abstract: Eccrine syringofibroadenoma (ESFA) is a rare eccrine tumor. We report the case of a 70-year-old woman who had presented a pincer nail deformity on the toes for 55 years and a left painless subungual tumor for 2 years. Histologic examination revealed branching anastomosing strands of epithelial cells with ductal structures in a fibrovascular stroma. The luminal cells showed positive staining for carcinoembryonic antigen, as in acrosyringeal cells and cells of dermal ducts. To our knowledge, our case is the first with a subungual location. In the context of chronic trauma due to a pincer nail, it may be classified in the reactive subtype recently described.
authors.affiliation: Department of Pathology, CHU Saint-Pierre, Brussels, Belgium. anne-theunis@stpierre-bru.be
authors.forename: A
authors.initials: A
authors.lastname: Theunis
authors.forename: J
authors.initials: J
authors.lastname: Andre
authors.forename: F
authors.initials: F
authors.lastname: Forton
authors.forename: J
authors.initials: J
authors.lastname: Wanet
authors.forename: M
authors.initials: M
authors.lastname: Song
mesh_terms: D006607:Adenoma, Sweat Gland / Q000473:pathology*; D000368:Aged; D004439:Eccrine Glands / Q000473:pathology; D005260:Female; D018226:Fibroadenoma / Q000473:pathology*; D006801:Humans; D009262:Nails / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*