title: Effect of stimulation parameters on intraoperative spinal cord evoked potential monitoring.
abstract: The purpose of this study was to investigate the effects of the stimulus parameters on spinal cord evoked potential (SCEP) and to recommend a practical epidural stimulation protocol for intraoperative spinal cord monitoring. This prospective study compared the latencies and amplitudes of SCEP obtained on epidural stimulation of 30 patients with scoliosis under anesthesia using different stimulus pulse duration and stimulation rates. SCEP was found to be undetectable with shorter stimulus duration (<0.05 ms). The SCEP latencies did not show any significant difference among different stimulation parameters. However, the SCEP amplitude showed significant changes with differing stimulus durations. The SCEP amplitudes were found to significantly decrease when the pulse durations become shorter than 0.2 ms. Stimulus parameters showed significant effects on SCEP amplitude but not latency. Stimulus rates in the range of 21 to 61 Hz are equivalent for quick and reliable detection of SCEP. Considering the short latency of SCEP, a pulse duration of 0.2 ms is recommended for SCEP using epidural stimulation.
authors.affiliation: Department of Orthopaedic Surgery, The University of Hong Kong, Hong, Kong. yhud@hkusua.hku.hk
authors.forename: Y
authors.initials: Y
authors.lastname: Hu
authors.forename: K D
authors.initials: KD
authors.lastname: Luk
authors.forename: Y W
authors.initials: YW
authors.lastname: Wong
authors.forename: W W
authors.initials: WW
authors.lastname: Lu
authors.forename: J C
authors.initials: JC
authors.lastname: Leong
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D002648:Child; D004558:Electric Stimulation / Q000379:methods; D019054:Evoked Potentials, Motor / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D016343:Monitoring, Intraoperative / Q000379:methods*; D012600:Scoliosis / Q000503:physiopathology* / Q000601:surgery*