[Effect of acupuncture on radial artery hemodynamics. Two controlled studies in pre-exposed and naive healthy subjects].
Palpation of the radial pulses is one of the most important techniques in traditional Chinese medicine. Two double-blind randomised trials of the effects of real and sham acupuncture on radial artery hemodynamics were conducted in 19 patients regularly exposed to acupuncture (sensitised subjects), and in 8 healthy subjects devoid of previous exposure (naive subjects), respectively. Radial artery diameter and pulse waveform was measured with a high-resolution echotracking system and aplanation tonometry, respectively, before and during a 20-minute's acupuncture period. In sensitised patients, arterial diameter significantly increased during real acupuncture, compared to the sham group (+7.5 +/- 2.8% vs -2.9 +/- 2.7%, respectively; p < 0.01). By contrast, in naive subjects, arterial diameter did not change during real or sham acupuncture. In both populations, no significant difference was observed between real and sham acupuncture, concerning the time-course of blood pressure, radial artery distensibility and pressure waveform. Our results demonstrate that real acupuncture can determine an objective vasodilatation of the radial artery in patients regularly exposed to acupuncture, but not in naive subjects.
Boutouyrie
P
P
Service de pharmacologie clinique et EMI-U 0107 INSERM, hôpital européen Georges-Pompidou, 75015 Paris.
Corvisier
R
R
Serreau
R
R
Azizi
M
M
Lemoine
D
D
Laloux
B
B
Hallouin
M C
MC
Laurent
S
S
D015670:Acupuncture Therapy; D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017534:Radial Artery / Q000502:physiology*; D016896:Treatment Outcome; D014664:Vasodilation