title: Laryngo-pharyngeal carcinoma in childhood.
abstract: Laryngo-pharyngeal carcinoma is rare in children. We present two cases of squamous cell carcinoma of the laryngopharynx in children less than 15 years of age. Both patients presented with a prolonged history of symptoms and extensive disease at diagnosis. Early visualisation the vocal cords with flexible larygnoscopy is important in children presenting with symptoms suggestive of laryngeal pathology. Long-term complications of definitive local therapy for laryngopharyngeal carcinoma are important in young children. Evidence from studies in adult patients suggests that adjuvant chemotherapy may play a role in laryngeal preservation in a select group of patients.
authors.affiliation: Clinical Fellow in Haematology and Oncology, Royal Children's Hospital, Melbourne, Australia.
authors.forename: C
authors.initials: C
authors.lastname: Barnes
authors.forename: M
authors.initials: M
authors.lastname: Sexton
authors.forename: A
authors.initials: A
authors.lastname: Sizeland
authors.forename: K
authors.initials: K
authors.lastname: Tiedemann
authors.forename: R G
authors.initials: RG
authors.lastname: Berkowitz
authors.forename: K
authors.initials: K
authors.lastname: Waters
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D002648:Child; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D007828:Laryngoscopy; D008297:Male; D010610:Pharyngeal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy