Ischemic heart disease associated with protein C deficiency.
Three patients of ischemic heart disease associated with protein C deficiency are reported. Although delayed diagnosis of protein C deficiency resulted in the failure of repeated interventions, coronary artery bypass grafting performed after making the correct diagnosis has led to satisfactory mid-term results under strict anticoagulation therapy. The level of protein C should be measured more frequently in the field of ischemic heart disease and earlier diagnosis of its deficiency should be made, because measurement of protein C does not cost much.
Ninomiya
M
M
Department of Cardiovascular Surgery, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, Japan. mikio-ninomiya@par.odn.ne.jp
Makuuchi
H
H
Ohtsuka
T
T
Takamoto
S
S
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001780:Blood Coagulation Tests; D001026:Coronary Artery Bypass; D023903:Coronary Restenosis / Q000097:blood / Q000175:diagnosis / Q000628:therapy; D003328:Coronary Thrombosis / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D020151:Protein C Deficiency / Q000097:blood / Q000175:diagnosis* / Q000628:therapy