title: Preadolescent children of substance-dependent fathers with antisocial personality disorder: psychiatric disorders and problem behaviors.
abstract: We compared psychiatric disorders and problem behavior scores in pre-adolescent children of fathers with alcohol or other drug dependence and ASP (SD+/ASP+), children whose fathers had substance dependence without ASP (SD+/ASP-), and children whose fathers were without either disorder (SD-/ASP-). SD+/ASP+ children showed elevated rates of major depression, conduct disorder, attention deficit hyperactivity disorder, oppositional defiant disorder, and separation anxiety disorder when compared to SD+/ASP- and SD-/ASP- children. SD+/ASP+ children had higher internalizing and externalizing problem behavior scores than the other two groups of children. The results suggest that SD+/ASP+ children are at significant risk for internalizing and externalizing psychopathology.
authors.affiliation: Department of Psychiatry, Temple University School of Medicine, Philadelphia, Pa., USA. Moss_h@mail.trc.upenn.edu
authors.forename: H B
authors.initials: HB
authors.lastname: Moss
authors.forename: D A
authors.initials: DA
authors.lastname: Baron
authors.forename: T L
authors.initials: TL
authors.lastname: Hardie
authors.forename: M M
authors.initials: MM
authors.lastname: Vanyukov
mesh_terms: D000987:Antisocial Personality Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D002648:Child; D002653:Child Behavior Disorders / Q000453:epidemiology / Q000523:psychology*; D016241:Child of Impaired Parents / Q000523:psychology*; D005220:Fathers / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012959:Socioeconomic Factors; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*