title: Brain MRI findings in influenza A-associated acute necrotizing encephalopathy of childhood.
abstract: Acute necrotizing encephalopathy following influenza A is frequently reported from Japan and Taiwan but is very rarely seen in Western countries. We describe a 10-year-old boy with acute necrotizing encephalopathy, who developed symmetrical thalamic and brain stem lesions seen on magnetic resonance imaging (MRI). Serological confirmation of influenza A was made 2 weeks after the onset of symptoms. The child made a full recovery. This case is interesting because of its rarity in European countries, the striking brain MRI findings and the good neurological outcome.
authors.affiliation: Second Department of Paediatrics, University of Athens, 'P & A Kyriakou' Children's Hospital, Athens, Greece. ppk@otenet.gr
authors.forename: K A
authors.initials: KA
authors.lastname: Voudris
authors.forename: A
authors.initials: A
authors.lastname: Skaardoutsou
authors.forename: I
authors.initials: I
authors.lastname: Haronitis
authors.forename: E A
authors.initials: EA
authors.lastname: Vagiakou
authors.forename: P M
authors.initials: PM
authors.lastname: Zeis
mesh_terms: D001933:Brain Stem / Q000473:pathology; D002648:Child; D004292:Dominance, Cerebral / Q000502:physiology; D004830:Epilepsy, Tonic-Clonic / Q000175:diagnosis; D005500:Follow-Up Studies; D006801:Humans; D009980:Influenza A virus; D007251:Influenza, Human / Q000175:diagnosis*; D004684:Leukoencephalitis, Acute Hemorrhagic / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D013788:Thalamus / Q000473:pathology