title: Gastric emptying after a new, more physiological anti-obesity operation: the Magenstrasse and Mill procedure.
abstract: The Magenstrasse and Mill (M&M) procedure for obesity is designed to preserve normal gastric emptying mechanisms. The hypothesis investigated in this study was that gastric emptying would be normal after the M&M gastroplasty. Gastric emptying studies were performed using both liquid and solid test meals, in ten morbidly obese patients (MO group) and in 13 patients after the M&M procedure (MM group). Seven people of normal weight served as controls and were matched for age, sex and height to the M&M and MO groups. Three years after the M&M procedure, mean (SD) weight loss was 42 (19) kg, with a mean loss of excess weight of 58% (20%). Gastric emptying half-times (t 1/2) are expressed in minutes, as median values (25th and 75th percentiles). The t 1/2 for solids was 97 (85-110) min in the control group, 140 (86-220) min in the MO group and 79 (46-150) min in the MM group. Median gastric emptying for solids was 0.7% (0.6%-0.8%) per minute in the control group, 0.5% (0.3%-0.8%) in the MO group and 0.9% (0.4%-1.4%) in the M&M group. There were no statistically significant differences in the emptying times of the three groups. It is concluded that the M&M procedure achieves acceptable weight loss, while preserving gastric emptying mechanisms and thus minimising possible side-effects such as vomiting, dumping and diarrhoea, which are common complications of gastric bypass procedures.
authors.affiliation: Leeds General Infirmary, UK. homepac@doctors.org.uk
authors.forename: A R
authors.initials: AR
authors.lastname: Carmichael
authors.forename: D
authors.initials: D
authors.lastname: Johnston
authors.forename: M C
authors.initials: MC
authors.lastname: Barker
authors.forename: R F
authors.initials: RF
authors.lastname: Bury
authors.forename: J
authors.initials: J
authors.lastname: Boyce
authors.forename: H
authors.initials: H
authors.lastname: Sue-Ling
mesh_terms: D000284:Administration, Oral; D000328:Adult; D004064:Digestive System / Q000000981:diagnostic imaging; D005260:Female; D005746:Gastric Emptying; D015391:Gastroplasty / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000008:administration & dosage; D013668:Technetium Tc 99m Aggregated Albumin / Q000008:administration & dosage; D016284:Technetium Tc 99m Pentetate / Q000008:administration & dosage
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D016284:Technetium Tc 99m Pentetate