title: Clinicopathologic study of 16 cases of primary tubal malignancy.
abstract: Sixteen cases of primary carcinoma of the fallopian tube were diagnosed and treated at Queen Mary Hospital, Hong Kong from July 1972 to June 1992 constituting 0.26% of the total gynecologic malignancies seen during that period. The average age was 61 years and the most common presenting symptom was abnormal vaginal bleeding. Preoperative diagnosis is difficult; in only one case was a diagnosis of malignancy made by cervical smear. An adnexal mass was detected in 13 of the cases (81.3%) either by clinical examination and/or ultrasonography. Therapy consisted of surgical resection, usually followed by various combinations of adjuvant radiation therapy and chemotherapy. The cumulative survival was 62%. In addition to the typical form of adenocarcinoma, one case of squamous cell carcinoma and a case of multifocal endometrioid adenocarcinoma were observed. One case of an apparently usual form of adenocarcinoma recurred as a heterologous malignant mixed Müllerian tumor 2 years after diagnosis. This series further emphasises the wide range of differentiation possible in the Müllerian system and the variety of neoplasms which may arise from it.
authors.affiliation: Departments of Pathology and Obstetrics and Gynaecology, University of Hong Kong; Department of Pathology, Kwong Wah Hospital.
authors.forename: A.N.Y.
authors.initials: AN
authors.lastname: Cheung
authors.forename: H.Y.S.
authors.initials: HY
authors.lastname: Ngan
authors.forename: D.
authors.initials: D
authors.lastname: Cheng
authors.forename: R.J.
authors.initials: RJ
authors.lastname: Collins
authors.forename: E.
authors.initials: E
authors.lastname: Gwi
authors.forename: L.C.
authors.initials: LC
authors.lastname: Wong
authors.forename: H.K.
authors.initials: HK
authors.lastname: Ma