[Tumor necrosis factor alpha and interleukin 1-beta in serum of patients with tick-borne encephalitis].
The purpose of this work was to evaluate the changes of IL-1 beta and TNF-alpha serum concentrations among patients with TBE (tick-borne encephalitis) of mild and severe clinical course. The detection of cytokines was performed by immunometric assay twice before and after treatment. There was no significant changes in IL-1 beta serum concentration after treatment in both groups of patients. But concentration of TNF-alpha decreased significantly after treatment in both groups of patients. It seems that changes of TNF-alpha concentration might be helpful in evaluation of efficacy of aseptic central nervous system treatment.
Kondrusik
M
M
Klinika Chorób Zakaznych i Neuroinfekcji AM w Białymstoku.
Pancewicz
S
S
Zajkowska
J
J
Hermanowska-Szpakowicz
T
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D004675:Encephalitis, Tick-Borne / Q000097:blood*; D005260:Female; D006801:Humans; D007375:Interleukin-1 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha