[Mother thyroid status and development of enzymes of initial and final phases of carbohydrate hydrolysis].
The daily treatment of a lactating mother with thyroxine 50 micrograms/100 g b.w. from the first to 21st day of lactation resulted in an increase of the thyroxine level in serum and earlier induction of alpha-glycosidases (pancreatic alpha-amylase and enteral maltase, saccharase) and in the earlier repression of beta-galactosidases (intestinal lactase) in rats. In contrast, sucklings fed by hypothyroid mothers showed a low level of thyroxine and a delayed induction of alpha-glucosidases but ameliorated the repression of lactase.
Kuchkareva
L S
LS
Institute of Physiology and Biophysics, Uzbekistan Republic Acad. Sci., 700095, Tashkent, 1 Niyazova St., Uzbekistan.
Rakhimov
K R
KR
D000818:Animals; D000831:Animals, Newborn; D050260:Carbohydrate Metabolism; D005260:Female; D005959:Glucosidases / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism; D006868:Hydrolysis; D007422:Intestines / Q000201:enzymology / Q000254:growth & development; D043322:Lactase; D007774:Lactation; D008895:Milk, Human / Q000378:metabolism*; D010179:Pancreas / Q000201:enzymology / Q000254:growth & development; D051381:Rats; D017208:Rats, Wistar; D013974:Thyroxine / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology; D000516:alpha-Amylases / Q000378:metabolism; D043324:beta-Fructofuranosidase; D001616:beta-Galactosidase / Q000378:metabolism
D005959:Glucosidases; D006026:Glycoside Hydrolases; D000516:alpha-Amylases; D043322:Lactase; D001616:beta-Galactosidase; D043324:beta-Fructofuranosidase; D013974:Thyroxine