title: Further evidence of association between behavioral inhibition and social anxiety in children.
abstract: OBJECTIVE
  The authors sought to examine psychopathological correlates of behavioral inhibition in young offspring of parents with panic disorder and/or major depression.
  
  
  METHODS
  Behavioral inhibition, determined by using standard laboratory observations, was assessed in four groups of children (age 2-6 years): 129 children of parents with both panic disorder and major depression, 22 children of parents with panic disorder alone, 49 children of parents with major depression alone, and 84 comparison children of parents with neither panic disorder nor major depression. Psychopathology in children > or =5 years was compared between children with behavioral inhibition (N=64) and without (N=152).
  
  
  RESULTS
  Social anxiety disorder (social phobia or avoidant disorder) was significantly more likely to be found in the children with behavioral inhibition (17%) than in those without (5%). Noninhibited children were significantly more likely than inhibited children to have disruptive behavior disorders (20% versus 6%, respectively) and had higher scores on the attention problems scale of the Child Behavior Checklist (mean=52.1 versus 50.8).
  
  
  CONCLUSIONS
  This study adds to the growing literature suggesting an association between behavioral inhibition and social anxiety disorder and an inverse relationship between inhibition and disruptive behavior disorders.
authors.affiliation: Department of Psychiatry, Massachusetts General Hospital, Boston, 02114, USA.
authors.forename: J
authors.initials: J
authors.lastname: Biederman
authors.forename: D R
authors.initials: DR
authors.lastname: Hirshfeld-Becker
authors.forename: J F
authors.initials: JF
authors.lastname: Rosenbaum
authors.forename: C
authors.initials: C
authors.lastname: Hérot
authors.forename: D
authors.initials: D
authors.lastname: Friedman
authors.forename: N
authors.initials: N
authors.lastname: Snidman
authors.forename: J
authors.initials: J
authors.lastname: Kagan
authors.forename: S V
authors.initials: SV
authors.lastname: Faraone
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000145:classification* / Q000453:epidemiology; D002648:Child; D002652:Child Behavior / Q000145:classification / Q000523:psychology; D016241:Child of Impaired Parents; D002675:Child, Preschool; D015897:Comorbidity; D019955:Conduct Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D007266:Inhibition, Psychological; D008297:Male; D016584:Panic Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology; D010290:Parents / Q000523:psychology; D010552:Personality Assessment; D010698:Phobic Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D013694:Temperament / Q000145:classification*