title: [Sex-related differences in blood and gonad levels of testosterone in silver fox fetuses].
abstract: The mass of silver fox fetuses of both sexes, their gonads, and adrenals, and the levels of testosterone in blood serum and in gonads and adrenals were determined from day 31 of gestation and every five days thereafter until its termination. Marked sex-related differences were revealed: the blood and gonad levels of testosterone in male fetuses were much higher than those in female fetuses. The fetal adrenals contained significantly less testosterone than the gonads. No sex-related differences in the content of testosterone in the fetal adrenals were found. No differences were found in the body and adrenal mass in female and male fetuses at all the developmental stages studied, while the mass of ovaries exceeded that of testes from day 45 of gestation. The data obtained suggest sex dimorphism in the production of testosterone by gonads in silver foxes appears after day 35 and appears to correspond to the period of morphological differentiation of gonads.
authors.affiliation: Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, pr. Akademika Lavrent'eva 10, Novosibirsk, 630090 Russia.
authors.forename: L V
authors.initials: LV
authors.lastname: Osadchuk
mesh_terms: D000311:Adrenal Glands / Q000196:embryology / Q000502:physiology; D000818:Animals; D001835:Body Weight; D005260:Female; D005589:Foxes / Q000196:embryology* / Q000502:physiology*; D008297:Male; D009929:Organ Size; D010053:Ovary / Q000196:embryology / Q000378:metabolism*; D011247:Pregnancy; D011270:Pregnancy, Animal; D012737:Sex Factors; D013737:Testis / Q000196:embryology / Q000378:metabolism*; D013739:Testosterone / Q000097:blood / Q000378:metabolism*
chemical_list: D013739:Testosterone