New experimental model of multiple myeloma.
NSO/1 (P3x63Ay 8Ut) and SP20 myeloma cells were inoculated to BALB/c OlaHsd mice. NSO/1 cells allowed adequate stage-by-stage monitoring of tumor development. The adequacy of this model was confirmed in experiments with conventional cytostatics: prospidium and cytarabine caused necrosis of tumor cells and reduced animal mortality.
Telegin
G B
GB
Branch of M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Pushchino. telegin@fibkh.serpukhov.su
Kalinina
A R
AR
Ponomarenko
N A
NA
Ovsepyan
A A
AA
Smirnov
S V
SV
Tsybenko
V V
VV
Homeriki
S G
SG
D000818:Animals; D004195:Disease Models, Animal; D051379:Mice; D008807:Mice, Inbred BALB C; D009101:Multiple Myeloma