Evaluation, selection, and follow-up of live kidney donors: a review of current practice in French renal transplant centres.
BACKGROUND
A resurgence of interest in the concept of live-donor renal transplantation has prompted a closer look at methods of live donor evaluation, selection, and follow-up. The aim of this study was to describe these methods in all 46 French renal transplant centres.


METHODS
Questionnaires were sent to all chief renal physicians.


RESULTS
The survey was completed by 78% of centres, which accounted for 95% of all live-donor renal transplants carried out in France in 1995 and 1996. There was a substantial variation in all three steps of live-donor management. For example, we observed variations in the screening for specific short- or long-term risk factors (especially cardiovascular or thrombotic risk factors and diabetes). In addition the exclusion criteria differed, especially the cut-off age for donation, which ranged from 45 to 75 years. The composition of teams evaluating and selecting potential donors and the role of the potential donors in the decision-making process varied greatly among centres. Finally, we observed less variation in the methods of donor follow-up.


CONCLUSIONS
The current survey revealed a marked disparity in the management of live donors in France. It raises the question of whether these practices should be codified into a set of guidelines for live-donor transplantation.
Gabolde
M
M
Laboratoire d'Ethique médicale et de Santé publique, Faculté de Médecine Necker, Université Paris V, France. martine.gabolde@bct.ap-hop-paris.fr
Hervé
C
C
Moulin
A M
AM
D000328:Adult; D000368:Aged; D003625:Data Collection; D005500:Follow-Up Studies; D005602:France; D006801:Humans; D016030:Kidney Transplantation; D019520:Living Donors; D008875:Middle Aged; D018579:Patient Selection; D011795:Surveys and Questionnaires; D009927:Tissue and Organ Procurement