title: [Transcranial doppler potentialities in asymptomatic "carotid disease"].
abstract: To elicit Transcranial doppler (TCD) potentialities in asymptomatic hemodynamically significant occlusive carotid diseases, twenty one patients with subclinical severe stenosis (more than 50%) of internal carotid artery (ICA) have been studied. After routine TCD, bilateral embolic monitoring of middle cerebral arteries (MCA) has been carried out. Besides, the functional test with breath-holding for cerebrovascular reserve (CVR) was made in all the patients. Control group consisted of 18 healthy volunteers without any ICA abnormality. The results of the study reveal that CVR--the index of brain circulation autoregulation safety--is more exact marker of its stability than a degree of extracranial carotid stenosis. TCD embolic monitoring of MCA enables not only to diagnose brain embolism but to elicit the embolic source origin (arterio-arterial or cardial). Thus, both TCD with breath-holding and TCD embolic monitoring facilitate identification of patients at high risk of ischemic events, which is important for brain ischemic disease prophylaxis.
authors.forename: A G
authors.initials: AG
authors.lastname: Nazinian
mesh_terms: D000368:Aged; D001921:Brain / Q000098:blood supply; D002339:Carotid Arteries / Q000503:physiopathology*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D005260:Female; D006439:Hemodynamics; D006706:Homeostasis; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods