Synthesis and stereochemical characterization of diastereomeric nucleoside-phosphorothioselenoates by NMR methods.
Synthesis and stereochemical characterization of enantiomerically pure nucleoside-phosphorothioselenoates are reported. The effects of solvent and temperature on the vicinal carbon-phosphorus couplings are described and the results are interpreted in terms of conformational changes influenced by stacking interactions between the bases and the phenyl rings.
Kajtár-Peredy
M
M
Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Budapest.
Tömösközi
I
I
Gács-Baitz
E
E
D057927:Hydrophobic and Hydrophilic Interactions; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D018036:Selenium Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D012997:Solvents; D013237:Stereoisomerism; D013696:Temperature
D009705:Nucleosides; D018036:Selenium Compounds; D012997:Solvents