title: Optimization of left ventricular function with carvedilol before high-risk cardiac surgery.
abstract: Patients with severe left ventricular dysfunction and symptomatic heart failure caused by ischemic or valvular heart disease face a high morbidity and mortality risk from cardiac surgery. We present data showing that excellent surgical outcome can be achieved after pre-treatment of such patients with carvedilol.
authors.affiliation: Cardiopulmonary Transplant Unit, St. Vincent's Hospital, Sydney, New South Wales, Australia.
authors.forename: E
authors.initials: E
authors.lastname: Kotlyar
authors.forename: P S
authors.initials: PS
authors.lastname: Macdonald
authors.forename: A M
authors.initials: AM
authors.lastname: Keogh
authors.forename: R H
authors.initials: RH
authors.lastname: Arnold
authors.forename: D J
authors.initials: DJ
authors.lastname: McCaffrey
authors.forename: M K
authors.initials: MK
authors.lastname: Wilson
authors.forename: P M
authors.initials: PM
authors.lastname: Spratt
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002227:Carbazoles / Q000627:therapeutic use*; D006348:Cardiac Surgical Procedures / Q000379:methods*; D000077261:Carvedilol; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000627:therapeutic use*; D012307:Risk Factors; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use; D016277:Ventricular Function, Left / Q000187:drug effects*
chemical_list: D000959:Antihypertensive Agents; D002227:Carbazoles; D011412:Propanolamines; D014665:Vasodilator Agents; D000077261:Carvedilol