title: Treatment of fetal congenital complete heart block with maternal administration of beta-sympathomimetics (terbutaline): a case report.
abstract: We report a case of fetal congenital heart block treated with maternal administration of beta-sympathomimetics. The case was diagnosed as fetal complete heart block associated with maternal anti-Ro/SS-A antibody at 22 weeks of gestation. By fetal sonography, the ventricular rate was revealed to be 60 beats/min and mild cardiomegaly was shown. We initiated maternal administration of a sympathomimetic, specifically terbutaline, to prevent fetal heart failure. An increase in the fetal ventricular rate and an improvement in cardiac function were both achieved during the treatment. A viable infant was delivered by an elective cesarean section without complications at term. Maternal administration of the beta-adrenergic agent terbutaline is suggested to be effective for improving fetal congenital heart block in order to prevent heart failure in utero.
authors.affiliation: Department of Obstetrics and Gynecology, Odawara Municipal Hospital, Odawara, Japan. HyoshidaSan@aol.com
authors.forename: H
authors.initials: H
authors.lastname: Yoshida
authors.forename: M
authors.initials: M
authors.lastname: Iwamoto
authors.forename: H
authors.initials: H
authors.lastname: Sakakibara
authors.forename: H
authors.initials: H
authors.lastname: Shigeta
authors.forename: F
authors.initials: F
authors.lastname: Hirahara
authors.forename: K
authors.initials: K
authors.lastname: Sato
mesh_terms: D000328:Adult; D015148:Cardiotocography; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005318:Fetal Heart / Q000000981:diagnostic imaging / Q000187:drug effects; D006327:Heart Block / Q000151:congenital* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006333:Heart Failure / Q000517:prevention & control; D006340:Heart Rate, Fetal / Q000187:drug effects; D006801:Humans; D011295:Prenatal Care; D013566:Sympathomimetics / Q000008:administration & dosage* / Q000627:therapeutic use*; D013726:Terbutaline / Q000008:administration & dosage* / Q000627:therapeutic use*; D016216:Ultrasonography, Prenatal
chemical_list: D013566:Sympathomimetics; D013726:Terbutaline