title: Comparison of electroencephalographic dipoles of interictal spikes from prolonged scalp video-electroencephalography and magnetoencephalographic dipoles from short-term recording in children with extratemporal lobe epilepsy.
abstract: We retrospectively compared electroencephalographic (EEG) dipoles of interictal spikes from prolonged video-EEG monitoring with magnetoencephalographic dipoles from short-term recording in four children with extratemporal lobe epilepsy. We analyzed both sets of dipoles using individual interictal spikes and single moving dipole modeling and evaluated the profiles of spike appearance, dipole position, and orientation in EEG and magnetoencephalography. We obtained more than 100 magnetoencephalographic spikes in two patients who manifested frequent interictal EEG spikes throughout both day and night but fewer than 40 magnetoencephalographic spikes in two patients who had interictal EEG spikes mainly during sleep. The dipole positions of EEG and magnetoencephalography were in close proximity and included in the surgical resection area. Most of the dipoles between EEG and magnetoencephalography were oriented perpendicularly. A combination of EEG dipole analysis from prolonged video-EEG monitoring and magnetoencephalographic dipole analysis provides complementary information for presurgical evaluation in children with intractable extratemporal lobe epilepsy.
authors.affiliation: Bloorview Epilepsy Research Program, Toronto, ON. 713643@ican.net
authors.forename: A
authors.initials: A
authors.lastname: Ochi
authors.forename: H
authors.initials: H
authors.lastname: Otsubo
authors.forename: R
authors.initials: R
authors.lastname: Sharma
authors.forename: A
authors.initials: A
authors.lastname: Hunjan
authors.forename: J T
authors.initials: JT
authors.lastname: Rutka
authors.forename: S H
authors.initials: SH
authors.lastname: Chuang
authors.forename: K
authors.initials: K
authors.lastname: Kamijo
authors.forename: T
authors.initials: T
authors.lastname: Yamazaki
authors.forename: P
authors.initials: P
authors.lastname: Quint
authors.forename: L
authors.initials: L
authors.lastname: Kurelowech
authors.forename: D F
authors.initials: DF
authors.lastname: Sobel
authors.forename: M H
authors.initials: MH
authors.lastname: Aung
authors.forename: O C
authors.initials: OC
authors.lastname: Snead
mesh_terms: D000293:Adolescent; D001931:Brain Mapping; D002648:Child; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D017034:Epilepsy, Frontal Lobe / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006801:Humans; D007902:Length of Stay; D015225:Magnetoencephalography; D008297:Male; D008991:Monitoring, Physiologic; D010296:Parietal Lobe / Q000503:physiopathology / Q000601:surgery; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012815:Signal Processing, Computer-Assisted; D014741:Video Recording