Timing of analog research in medicinal chemistry.
Analog research plays an important role in medicinal chemistry. Having identified a new target in molecular biology many similar lead compounds are synthesized resulting in closely related products on the market. Another approach is the further optimising of an existing drug in order to improve on the original. In some cases these two approaches overlap. The question of timing and the importance of analog research are analyzed in this paper.
Fischer
J
J
Research Laboratory of Gedeon Richter Ltd., Budapest, Hungary.
Gere
A
A
D000818:Animals; D006801:Humans; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D010600:Pharmacology / Q000639:trends*; D012106:Research
D004364:Pharmaceutical Preparations