title: Expression of MUL, a gene encoding a novel RBCC family ring-finger protein, in human and mouse embryogenesis.
abstract: We studied the expression of MUL, a gene encoding a novel member of the RING-B-Box-Coiled Coil family of zinc finger proteins that underlies the human inherited disorder, Mulibrey nanism. In early human and mouse embryogenesis MUL is expressed in dorsal root and trigeminal ganglia, liver and in epithelia of multiple tissues.
authors.affiliation: Folkhälsan Institute of Genetics and Department of Medical Genetics, Biomedicum Helsinki, Haartmaninkatu 8, 00014 University of Helsinki, Helsinki, Finland.
authors.forename: A E
authors.initials: AE
authors.lastname: Lehesjoki
authors.forename: V A
authors.initials: VA
authors.lastname: Reed
authors.forename: R
authors.initials: R
authors.lastname: Mark Gardiner
authors.forename: N D
authors.initials: ND
authors.lastname: Greene
mesh_terms: D000818:Animals; D004392:Dwarfism / Q000235:genetics; D004848:Epithelium / Q000196:embryology; D005727:Ganglia, Spinal / Q000196:embryology; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D017403:In Situ Hybridization; D008099:Liver / Q000196:embryology; D051379:Mice; D009687:Nuclear Proteins / Q000235:genetics*; D012668:Trigeminal Ganglion / Q000196:embryology; D000070584:Tripartite Motif Proteins; D044767:Ubiquitin-Protein Ligases; D016335:Zinc Fingers / Q000235:genetics
chemical_list: D009687:Nuclear Proteins; D000070584:Tripartite Motif Proteins; C411745:TRIM37 protein, human; D044767:Ubiquitin-Protein Ligases