Preparation and antibacterial evaluation of some nitrone derivative and their zirconium (IV) chloride complexes.
Some new complexes of the general formula ZrCl3.L where L = [N-(p-anisole)-alpha-(2-xanthatophenyl)nitrone], L1, and [N-(p-chlorophenyl)-alpha-(2-xanthatophenyl)nitrone], L2, have been prepared and characterized by elemental analysis, i.r. and molar conductances. The antibacterial activities of these compounds have been studied against five species of bacteria in vitro at concentration ranging from 1-10 micrograms/ml. A remarkable activity was exhibited by the ligand L2 against Staph. aureus and Bacillus subtilis.
Khallow
K I
KI
Dept. of Chemistry, College of Education, University of Mosul, Iraq.
Sulayman
K D
KD
Ezzat
S S
SS
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D003470:Culture Media; D008024:Ligands; D009589:Nitrogen Oxides / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared; D015040:Zirconium / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D003470:Culture Media; D008024:Ligands; D009589:Nitrogen Oxides; C015388:nitrones; D015040:Zirconium