[The role of cytokines in cardiovascular diseases].
Cytokines are the regulatory peptides produced, excreted and influencing function of many cells types in human including endothelium and cardiomyocytes. This is why their role in the etiopathology of cardiovascular diseases is so important and new discoveries confirm their contribution to it. Cytokines worsen the outcome of heart failure, intensify remodeling of vascular wall after PTCA and provoke instability of atherosclerotic plaque. On the other hand some of their properties like ability to force neovascularisation in the ischaemic parts of heart are already used in clinical trials. New discoveries considering cytokines are sure to bring us near to better understanding of their role in cardiovascular disease pathology and new ways of therapy.
Kuliczkowski
W
W
Katedra i Klinika Kardiologii AM we Wrocławiu.
D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D009130:Muscle, Smooth / Q000378:metabolism; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000378:metabolism* / Q000601:surgery; D010982:Platelet-Derived Growth Factor / Q000378:metabolism
D016207:Cytokines; D010982:Platelet-Derived Growth Factor