Novel ceramides from the fungus Lactarium volemus.
Two novel ceramides, lactariamides A (N-2'-hydroxytetracosanoyl-2-amino-3,4-epoxyoctadecan-1-ol (1)) and B ((4E,8E)-N-2'-hydroxyoctadecanoyl-2-amino-9-methyl-4,8-octadecadine-1,3-diol (2)), were isolated from the fungus Lactarium volemus, together with a known compound, cerebroside D (3). Their structures were determined on the basis of chemical evidence and spectral methods.
Yue
J M
JM
Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 294 Taiyuan Road, Shanghai, 200031, People's Republic of China. jmyue@mail.shcnc.ac.cn
Fan
C Q
CQ
Xu
J
J
Sun
H D
HD
D000363:Agaricales / Q000737:chemistry*; D002518:Ceramides / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D002554:Cerebrosides; D002681:China; D002845:Chromatography; D002855:Chromatography, Thin Layer; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
D002518:Ceramides; D002554:Cerebrosides; C438630:cerebroside D; C438629:lactariamide A; C438631:lactariamide B