Monoamine oxidase activity, lipid peroxidation, and morphological changes in human hypothalamus during aging.
Progressive gliosis of the hypothalamus during aging in humans is accompanied by activation of monoamine oxidase B activity, intensification of lipid peroxidation, and inhibition of SDH. Density of capillaries decreases. The role of monoamine oxidase B in the induction of lipid peroxidation is discussed.
Shemyakov
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SE
Department of Human Anatomy, Chelyabinsk State Medical Academy.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism / Q000473:pathology; D015536:Down-Regulation; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000378:metabolism / Q000473:pathology; D015227:Lipid Peroxidation; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000378:metabolism*; D013385:Succinate Dehydrogenase / Q000378:metabolism
D013385:Succinate Dehydrogenase; D008995:Monoamine Oxidase