title: The influence of tumor necrosis factor-alpha and interleukin-10 gene promoter polymorphism on the inflammatory response in experimental human endotoxemia.
abstract: In this study, we show that there is no correlation between tumor necrosis factor-alpha gene promoter polymorphism at position -308, interleukin-10 gene promoter polymorphism at position -1082, and the cytokine levels they produce in the human endotoxemia model.
authors.affiliation: Intensive and Respiratory Care Unit, Department of Internal Medicine, Groningen University Hospital, Groningen, The Netherlands. j.w.fijen@int.azg.nl
authors.forename: J W
authors.initials: JW
authors.lastname: Fijen
authors.forename: J E
authors.initials: JE
authors.lastname: Tulleken
authors.forename: B G
authors.initials: BG
authors.lastname: Hepkema
authors.forename: T S
authors.initials: TS
authors.lastname: van der Werf
authors.forename: J J
authors.initials: JJ
authors.lastname: Ligtenberg
authors.forename: J G
authors.initials: JG
authors.lastname: Zijlstra
mesh_terms: D000328:Adult; D019446:Endotoxemia / Q000097:blood / Q000235:genetics / Q000276:immunology*; D006801:Humans; D016753:Interleukin-10 / Q000097:blood / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis / Q000235:genetics*
chemical_list: D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10