title: Normalization of auditory evoked potential and visual evoked potential in patients with idiot savant.
abstract: OBJECTIVE
  To investigate the variations of auditory evoked potentials (AEP) and visual evoked potentials (VEP) of patients with idiot savant (IS) syndrome.
  
  
  METHODS
  Both AEP and VEP were recorded from 7 patients with IS syndrome, 21 mentally retarded (MR) children without the syndrome and 21 normally age-matched controls, using a Dantec concerto SEEG-16 BEAM instrument.
  
  
  RESULTS
  Both AEP and VEP of MR group showed significantly longer latencies (P1 and P2 latencies of AEP, P < 0.01; N1 and N2 latencies of VEP, P < 0.01/0.05), lower P2 amplitudes (P < 0.01) and higher P3 amplitudes (P < 0.01), as compared with normal controls. But none of above-mentioned changes was found with IS group. Almost all MR patients (90.1%) presented P4 component in both AEP and VEP, which was also in sharp contrast with its incidence in other 2 groups (IS: 14.3%; normal controls: 9.5%).
  
  
  CONCLUSIONS
  Patients with idiot savant syndrome presented normalized AEP and VEP.
authors.affiliation: Shanghai Institute of Mental Health, Shanghai 200030, China.
authors.forename: X
authors.initials: X
authors.lastname: Chen
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: F
authors.initials: F
authors.lastname: Lou
authors.forename: J
authors.initials: J
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D002648:Child; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology*; D008297:Male; D013577:Syndrome