[Verification of a new processing technology for pilot production of Aconitum coreanum (Lévl.) Raipaics].
The stability and feasibility of a new technology for processing Aconitum coreanum have been tested for pilot production by determining the components, toxicity(LD50) and traditional identification standard. The result shows that the contents of guanfu A and total alkaloid between the small trial and pilot production are slightly different and LD50 are nearly similar. Hypaconitine was not found in all kinds of processed products. The new technology has thus been proved stable and feasible.
Mao
S
S
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700.
Cheng
L
L
Wu
L
L
Lu
Z
Z
Ye
Z
Z
Zhu
D
D
Wang
J
J
D000470:Alkaloids / Q000032:analysis; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000633:toxicity; D005260:Female; D006576:Heterocyclic Compounds, 4 or More Rings; D006358:Hot Temperature; D007928:Lethal Dose 50; D019684:Magnoliopsida / Q000737:chemistry; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*
D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D006576:Heterocyclic Compounds, 4 or More Rings; C040615:Guan-fu base A