Identification of the configuration of neosartorin by long-range nuclear Overhauser effect measurements.
The relative configuration of the two xanthene units of neosartorin, a new ergochrome biosynthesised by the soil mould Neosartorya fischeri, was determined using a 1D double-pulsed field gradient spin-echo NOESY experiment. It was found that both units have the same relative stereochemistry. Long-range nonbonding interactions between the substituents of different xanthene units stabilise the nonplanar configuration of the two aromatic rings A and A' connecting both monomer units of neosartorin.
Liptaj
T
T
Slovak University of Technology, Faculty of Chemical Technology, Central Laboratories, Bratislava, Slovakia. liptaj@chtf.stuba.sk
Pham
T N
TN
Proksa
B
B
Uhrín
D
D