title: Arylation of halogenated pyrimidines via a Suzuki coupling reaction.
abstract: The Suzuki coupling reaction has been used extensively for the synthesis of a wide variety of unsymmetrical biaryl compounds. We have extended this reaction to demonstrate the utility of preparing monophenyl-, diphenyl-, or triphenylpyrimidine depending on the reaction conditions. Further, it has been shown that chloropyrimidine substrates are preferable over iodo-, bromo-, or fluoropyrimidines.
authors.affiliation: Malcolm H. Filson Laboratories, Department of Chemistry, Central Michigan University, Mt. Pleasant, Michigan 48859, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Schomaker
authors.forename: T J
authors.initials: TJ
authors.lastname: Delia