title: Orbital apex syndrome due to aspergillosis: case report.
abstract: We report the case of a 73-year-old female who presented facial numbness and pain in the first division of the trigeminal nerve, ptosis, diplopia and visual loss on the right side for the previous four months. The neurological, radiological and histological examination demonstrated a rare case of invasive fungal aspergillosis of the central nervous system, causing orbital apex syndrome, later transformed in temporal brain abscess. She died ten months later due to respiratory and renal failure in spite of specific antimycotic therapy.
authors.affiliation: Disciplina de Neurocirurgia, Departamento Neurologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, SP, Brasil. yvens@uol.com.br
authors.forename: Y B
authors.initials: YB
authors.lastname: Fernandes
authors.forename: R
authors.initials: R
authors.lastname: Ramina
authors.forename: G
authors.initials: G
authors.lastname: Borges
authors.forename: L S
authors.initials: LS
authors.lastname: Queiroz
authors.forename: M V
authors.initials: MV
authors.lastname: Maldaun
authors.forename: J A
authors.initials: JA
authors.lastname: Maciel
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000150:complications* / Q000473:pathology; D001922:Brain Abscess / Q000382:microbiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009901:Optic Nerve Diseases / Q000209:etiology; D009916:Orbital Diseases / Q000209:etiology* / Q000473:pathology; D013577:Syndrome