title: Electroretinogram contact lens electrode with tri-color light-emitting diode.
abstract: OBJECTIVE
  This study was performed to evaluate a new electroretinogram (ERG) contact lens electrode containing four light-emitting diodes (LEDs) that are used for both stimulus and background light.
  
  
  METHODS
  The luminance of each LED could be changed independently and used as stimulus light. Red, blue, bright white, and flickering ERGs were recorded in 12 normal subjects and two patients with progressive cone dystrophy. The long-duration light stimuli separated the on- and off-responses of the ERG. This equipment is not according to the ISCEV standard.
  
  
  RESULTS
  The tri-color LED electrode contact lens can efficiently produce and record ERG responses. Off-responses were recordable separately from on-responses by lengthening the stimulus duration.
  
  
  CONCLUSIONS
  This combined stimulus-electrode system is compact and portable. Combined with the portable amplifier and the recorder, the ERGs can be recorded easily in an operating room, at patients' bedside, and in remote locations away from clinics and hospitals.
authors.affiliation: Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School and Schepens Retina Associates, Boston, Massachusetts, USA. s-miz@jg7.so-net.ne.jp
authors.forename: S
authors.initials: S
authors.lastname: Mizunoya
authors.forename: K
authors.initials: K
authors.lastname: Kuniyoshi
authors.forename: M
authors.initials: M
authors.lastname: Arai
authors.forename: K
authors.initials: K
authors.lastname: Tahara
authors.forename: T
authors.initials: T
authors.lastname: Hirose
mesh_terms: D000328:Adult; D003261:Contact Lenses; D004566:Electrodes; D004596:Electroretinography / Q000295:instrumentation*; D006801:Humans; D008027:Light; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000502:physiology*; D017949:Retinal Cone Photoreceptor Cells / Q000503:physiopathology; D012162:Retinal Degeneration / Q000503:physiopathology