title: Periodontal disease and periodontal management in patients with cancer.
abstract: Periodontal infection may exacerbate during cancer therapy and may result in oral pain and infection, and systemic infection, which may cause morbidity and can lead to mortality in neutropenic cancer patients. Periodontal disease in head and neck cancer patients treated with radiation therapy may lead to acute and chronic complications. The literature was reviewed by a search of Medline of the National Library of Medicine. The search was conducted to identify publications assessing periodontal disease in cancer patients. In addition, a review of papers referenced in the retrieved papers was conducted to identify additional publications for review. Periodontal disease should be assessed and managed prior to medical treatment of cancer for those with oropharyngeal cancer, and for patients in whom neutropenia may develop during treatment. Pretreatment assessment and management, and maintenance of oral hygiene have been shown to be effective in preventing oral and systemic complications during treatment. A complete oral and periodontal examination is appropriate for all patients planned to receive head and neck radiation therapy and those to be treated with medical protocols that are anticipated to result in neutropenia. Oral and periodontal care must continue following cancer therapy, and requires that the health care provider have an understanding of the malignant disease, oral manifestations of the disease, medical management of the disease, and of the oral complications that may develop.
authors.affiliation: British Columbia Cancer Agency, Vancouver Hospital and Health Sciences Centre, 600 West 10th Avenue, Vancouver, BC, Canada V5Z 4E6. jepstein@bccancer.bc.ca
authors.forename: J B
authors.initials: JB
authors.lastname: Epstein
authors.forename: P
authors.initials: P
authors.lastname: Stevenson-Moore
mesh_terms: D019072:Antibiotic Prophylaxis; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology; D006258:Head and Neck Neoplasms / Q000150:complications* / Q000188:drug therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D006801:Humans; D007938:Leukemia / Q000150:complications / Q000188:drug therapy; D010510:Periodontal Diseases / Q000150:complications* / Q000628:therapy; D011878:Radiotherapy / Q000009:adverse effects; D013283:Stomatitis, Herpetic / Q000209:etiology; D014081:Tooth Extraction; D019172:Transplantation Conditioning / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents