title: A method of simulating dynamic multileaf collimators using Monte Carlo techniques for intensity-modulated radiation therapy.
abstract: A method of modelling the dynamic motion of multileaf collimators (MLCs) for intensity-modulated radiation therapy (IMRT) was developed and implemented into the Monte Carlo simulation. The simulation of the dynamic MLCs (DMLCs) was based on randomizing leaf positions during a simulation so that the number of particle histories being simulated for each possible leaf position was proportional to the monitor units delivered to that position. This approach was incorporated into an EGS4 Monte Carlo program, and was evaluated in simulating the DMLCs for Varian accelerators (Varian Medical Systems, Palo Alto. CA, USA). The MU index of each segment, which was specified in the DMLC-control data, was used to compute the cumulative probability distribution function (CPDF) for the leaf positions. This CPDF was then used to sample the leaf positions during a real-time simulation, which allowed for either the step-shoot or sweeping-leaf motion in the beam delivery. Dose intensity maps for IMRT fields were computed using the above Monte Carlo method, with its accuracy verified by film measurements. The DMLC simulation improved the operational efficiency by eliminating the need to simulate multiple segments individually. More importantly, the dynamic motion of the leaves could be simulated more faithfully by using the above leaf-position sampling technique in the Monte Carlo simulation.
authors.affiliation: Department of Radiation Physics. The University of Texas MD Anderson Cancer Center, Houston, USA. hliu@mdanderson.org
authors.forename: H H
authors.initials: HH
authors.lastname: Liu
authors.forename: F
authors.initials: F
authors.lastname: Verhaegen
authors.forename: L
authors.initials: L
authors.lastname: Dong
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D003198:Computer Simulation; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008962:Models, Theoretical; D009010:Monte Carlo Method; D009369:Neoplasms / Q000532:radiotherapy; D010315:Particle Accelerators; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D020266:Radiotherapy, Conformal / Q000379:methods*; D011882:Radiotherapy, High-Energy; D012542:Scattering, Radiation