title: Outcomes of laparoscopic fundoplication for gastroesophageal reflux disease and paraesophageal hernia.
abstract: BACKGROUND
  Laparoscopic fundoplication has become the standard for operative treatment of gastroesophageal reflux disease (GERD).
  
  
  METHODS
  We reviewed our experience with 1,000 consecutive patients receiving laparoscopic fundoplication for GERD (n = 882) or paraesophageal hernia (n = 118) between October 1991 and July 1999. Patients with achalasia and failed fundoplication were excluded from analysis. All the patients were evaluated preoperatively by upper endoscopy, esophageal manometry, and barium swallow. After 1994, 24-h pH monitoring was performed selectively in patients with extraesophageal symptoms and/or those without erosive esophagitis. There were 490 men 510 women in this review. Their mean age was 49 years. Procedures performed were 360 degrees floppy fundoplication (n = 879), 360 degrees fundoplication without fundus mobilization (Rossetti) (n = 22), 270 degrees posterior fundoplication (n = 96), and anterior fundoplication (n = 2). Esophageal lengthening procedure (Collis gastroplasty) was performed in combination with fundoplication in 15 patients. In seven patients the treatment was converted to open fundoplication.
  
  
  RESULTS
  The average length of hospitalization was 2.2 days, and 136 patients stayed longer than 2 days. Major complications occurred in 21 patients: esophageal perforation (n= 10), acute paraesophageal herniation (n = 4), splenic bleeding (n = 2), cardiac arrest (n = 1), pneumonia (n = 3), and testicular abscess (n = 1). Additional operations were required to manage the complications in 14 patients (70%): Four of these procedures were performed emergently, and 10 patients underwent reoperation between 6 h and 10 days. There were three deaths, all of which involved elderly patients with paraesophageal hernia. There were 35 late failures requiring reoperation for recurrence of GERD or development of new symptoms: The treatment of 32 patients was revised laparoscopically, and 4 patients required laparotomy. Beyond 1 year (median follow-up period, 27 months), 94% of the reviewed patients were satisfied with their surgical outcome.
authors.affiliation: Department of Surgery and Medicine, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Terry
authors.forename: C D
authors.initials: CD
authors.lastname: Smith
authors.forename: G D
authors.initials: GD
authors.lastname: Branum
authors.forename: K
authors.initials: K
authors.lastname: Galloway
authors.forename: J P
authors.initials: JP
authors.lastname: Waring
authors.forename: J G
authors.initials: JG
authors.lastname: Hunter
mesh_terms: D000368:Aged; D001466:Barium Sulfate; D001471:Barrett Esophagus / Q000453:epidemiology; D015897:Comorbidity; D004940:Esophageal Stenosis / Q000453:epidemiology; D005260:Female; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D006304:Health Status; D006551:Hernia, Hiatal / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008365:Manometry; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012086:Reoperation; D016896:Treatment Outcome
chemical_list: D001466:Barium Sulfate