Measuring structural changes in the optic nerve head and retinal nerve fibre layer.
OBJECTIVE
Assessing structural changes in the optic nerve is fundamental to the diagnosis and follow-up of glaucoma. Many clinical decisions are based on the determination of stability or non-stability of glaucomatous damage. Retinal nerve fibre layer (RNFL) and optic disc photographs are very useful in clinics but their assessment is based on subjective evaluation.


METHODS
Confocal scanning laser ophthalmoscope and confocal scanning laser polarimetry are available and allow objective and quantitative analysis of the optic nerve. These instruments are currently being assessed for their use in glaucoma follow-up.


CONCLUSIONS
This article summarises their advantages and limitations in performing the difficult task of detecting progression or changes over time.
Antón
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Institute of Applied Ophthalmobiology, University of Valladolid, Valladolid, Hospital de la Esperanza, Universidad Autónoma de Barcelona, Spain. aanton@retemail.es
D003941:Diagnostic Techniques, Ophthalmological; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D007368:Interferometry; D008027:Light; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D014054:Tomography