Pink snapper (Pagrus auratus) as a bioindicator of aquatic. Environmental health in Western Australia.
Pink snapper (Pagrus auratus), an endemic Western Australian fish species, was tested for its potential as a bioindicator of aquatic environmental health. Mixed function oxygenase (MFO) induction (as a biomarker of exposure), and sorbitol dehydrogenase (SDH) activity (as a biomarker of liver damage) were of special interest to the study as these biochemical tools have not been validated for any Western Australian fish species. Juvenile pink snapper were injected intraperitoneally (i.p.) with 0, 10, 100, 500, and 1000 micrograms PCB-126 per kilogram. Fish were sacrificed 10 days postinjection, and livers and blood samples were collected for MFO and SDH analysis, respectively. Doses of 10 and 100 micrograms PCB-126 per kilogram caused the highest MFO induction, while doses of 0 and 1000 micrograms PCB-126 per kilogram did not result in higher MFO activity relative to carrier-injected control fish. SDH activities were not significantly different among treatments indicating that hepatocellular damage was not responsible for the reduced MFO activity at the highest dose. The result of the study demonstrates that pink snapper may potentially be used as a bioindicator species in Western Australia when MFO is used as a biomarker.
Tugiyono
Department of Environmental Biology, Curtin University of Technology, Perth, Western Australia 6845.
Gagnon
M M
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D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D004305:Dose-Response Relationship, Drug; D004784:Environmental Monitoring; D004965:Estrogen Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D007263:Infusions, Parenteral; D007064:L-Iditol 2-Dehydrogenase / Q000032:analysis / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000032:analysis / Q000378:metabolism*; D010473:Perciformes; D011078:Polychlorinated Biphenyls / Q000008:administration & dosage / Q000009:adverse effects*; D014874:Water Pollutants, Chemical / Q000009:adverse effects; D014904:Western Australia
D015415:Biomarkers; D004965:Estrogen Antagonists; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls; D006899:Mixed Function Oxygenases; D007064:L-Iditol 2-Dehydrogenase; C023035:3,4,5,3',4'-pentachlorobiphenyl