Fused cinnolines: synthesis and biological activity.
Cinnolines, in general, have been reviewed in details over the last decades. Fused cinnolines have shown remarkable biological activities. Some fused cinnolines received approval as bioactive drug or still in advanced clinical trials. This is prompted the need to review fused cinnolines from the synthetic and biological points of view.
Bekhit
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Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Egypt.
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D011804:Quinolines