Lumpidin, a novel biomarker of some ochratoxin a producing penicillia.
The novel compound lumpidin (1) has been isolated as a major compound from an isolate of Penicillium nordicum. Compound 1 is a diketopiperazine with a unique ring system likely to be a condensate of one mole each of L-tryptophan, L-phenylalanine, and L-homo-proline. The fact that 1 has been detected from only three out of sixteen isolates of P. nordicum indicates that lumpidin-producing isolates might represent a separate and third ochratoxin A producing Penicillium species.
Larsen
T O
TO
The Mycology Group, BioCentrum-DTU, Søltofts Plads, Technical University of Denmark, 2800 Lyngby, Denmark. thomas.o.larsen@biocentrum.dtu.dk
Petersen
B O
BO
Duus
J Ø
JØ
D015415:Biomarkers / Q000032:analysis* / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009793:Ochratoxins / Q000096:biosynthesis*; D010407:Penicillium / Q000737:chemistry* / Q000378:metabolism; D010879:Piperazines / Q000737:chemistry / Q000302:isolation & purification*
D015415:Biomarkers; D007093:Imidazoles; D009793:Ochratoxins; D010879:Piperazines; C439410:lumpidin; C025589:ochratoxin A