[Protective effects of folium Ginkgo extract on experimental cerebral ischemia of mice].
Folium Ginkgo extract(EGb761) has been proved able to significantly prolong the survival time of mice suffering from cerebral ischemia induced by occluding bilateral common carotids, and reduce the inhibition of cerebral GSH-Px and Na(+)-K(+)-ATPase activities during reperfusion processes of these mice. Pretreatment with EGb761 also helps alleviate the subcellular damages in hippocampus of cerebral ischemic mice.
Wang
H
H
Medical School of Nanjing University, Nanjing 210093.
Wang
Y
Y
Zhao
X
X
Zhang
Z
Z
Miao
Y
Y
D000818:Animals; D002545:Brain Ischemia / Q000201:enzymology* / Q000473:pathology; D005260:Female; D016166:Free Radical Scavengers / Q000494:pharmacology*; D020441:Ginkgo biloba / Q000737:chemistry*; D005979:Glutathione Peroxidase / Q000378:metabolism; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D011897:Random Allocation; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D000096983:Ginkgo Extract
D016166:Free Radical Scavengers; D005979:Glutathione Peroxidase; D010936:Plant Extracts; D000254:Sodium-Potassium-Exchanging ATPase; C063170:Ginkgo biloba extract; D000096983:Ginkgo Extract