title: Acute mania and hemichorea.
abstract: A 61-year-old man suddenly became euphoric and talkative. Later the same day, he developed hemichoreic movements of the left limbs. The patient fulfilled the DSM-IV criteria for a manic episode by abnormally and persistently elevated mood, decreased need for sleep, high distractibility, pressured speech, increased goal-directed activity, and hypersexuality. The mood changes persisted for several weeks. Magnetic resonance imaging of the brain showed a right thalamic infarction. The co-occurrence of hemichorea and mania caused by focal thalamic lesion is very rare. It may be explained by dysfunction in basal ganglia thalamocortical circuitry.
authors.affiliation: Department of Neurology, Hillel Yaffe Medical Center, Hadera, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Inzelberg
authors.forename: P
authors.initials: P
authors.lastname: Nisipeanu
authors.forename: D
authors.initials: D
authors.lastname: Joel
authors.forename: M
authors.initials: M
authors.lastname: Sarkantyus
authors.forename: R L
authors.initials: RL
authors.lastname: Carasso
mesh_terms: D000208:Acute Disease; D001714:Bipolar Disorder / Q000175:diagnosis*; D002819:Chorea / Q000175:diagnosis*; D005059:Euphoria; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013788:Thalamus / Q000473:pathology