Malignancies arising in oncocytic schneiderian papillomas: a report of 2 cases and review of the literature.
Oncocytic schneiderian papillomas (OSPs) are uncommon benign neoplasms that arise from the sinonasal schneiderian epithelium. Malignancies arising in OSPs are rare, and, to our knowledge, only 14 such instances have been reported in the medical literature. We report 2 additional cases--a small cell carcinoma and a sinonasal undifferentiated carcinoma arising in OSPs and presenting synchronously with the benign neoplasm. The potential for malignant transformation in OSPs is small, but warrants that these papillomas be completely excised to exclude a coexisting carcinoma.
Maitra
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Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. aiims1742@hotmail.com
Baskin
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LB
Lee
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EL
D000368:Aged; D015415:Biomarkers; D001706:Biopsy; D002277:Carcinoma / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000473:pathology*; D009669:Nose Neoplasms / Q000473:pathology* / Q000601:surgery; D010212:Papilloma / Q000473:pathology* / Q000601:surgery; D010256:Paranasal Sinuses / Q000473:pathology*
D015415:Biomarkers; C400901:CAM 5.2 antigen; D007633:Keratins