Synthesis and structure determination of some oxadiazole-2-thione and triazole-3-thione galactosides.
The syntheses of 5-pyridyl-3(beta-D-galactopyranosyl)-1,3,4-oxadiazole-2-thiones 3a-3c and 5-pyridyl-2(beta-D-galactopyranosyl)-4-benzyl-1,2, 4-triazole-3-thiones 6a-6c are reported. The existence of N-galactosides--not S-galactosides--was proven by IR and 15N NMR spectroscopy. The structures of the final products and the intermediates were elucidated by IR, 1H, 13C and 15N NMR spectroscopy and mass spectrometry.
Ahmad
R
R
Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan.
Iqbal
R
R
Akhtar
H
H
Zia-ul-Haq
Duddeck
H
H
Stefaniak
L
L
Sitkowski
J
J
D002855:Chromatography, Thin Layer; D005697:Galactosides / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010069:Oxadiazoles / Q000138:chemical synthesis / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013871:Thiones / Q000138:chemical synthesis / Q000737:chemistry*; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry*
D005697:Galactosides; D010069:Oxadiazoles; D013871:Thiones; D014230:Triazoles