title: Surgery for pulmonary aspergilloma in post-tuberculous vs. immuno-compromised patients.
abstract: OBJECTIVE
  To compare the outcome of surgical resection for aspergilloma between patients with post-tuberculous complex and neutropenia.
  
  
  METHODS
  We retrospectively reviewed our surgical experience with pulmonary resection for aspergilloma in 30 patients. Of the 20 patients with complex aspergilloma complicating healed tuberculosis (group 1), 14 were male and six were female with an average age of 54 years (SD 7). The indication for surgery was recurrent haemoptysis in all and there were 17 lobectomies, two pneumonectomies and one bilateral lobectomy. There were ten patients with acute myeloid or lymphoid leukemia (group 2), six male and four female with an average age of 26 years (SD 4). Twelve lesions required lobectomy in eight and wedge excision in four.
  
  
  RESULTS
  In group 1 there was one post-operative death (5%), in a patient with massive haemoptysis and completely destroyed lungs with bilateral upper lobe aspergilloma secondary to pneumonia. Morbidity accounted for 25% (five patients), two required re-exploration for bleeding, two had prolonged air leak more than 7 days and one developed empyema. The later was treated with drainage and rib resection. One patient had recurrence of haemoptysis during the follow up period (mean 42 months). In group 2 there was no mortality or morbidity and six patients proceeded to bone marrow transplantation with no complication or recurrence.
  
  
  CONCLUSIONS
  Surgical resection for pulmonary aspergilloma in selected patients provides the best chance of cure. Pulmonary resection for post-tuberculous complex aspergilloma is associated with higher morbidity than resection for immuno-compromised patients.
authors.affiliation: King Khalid University Hospital, P.O. Box 18097, Riyadh 11415, Saudi Arabia. kkattan@kfshrc.edu.sa
authors.forename: K
authors.initials: K
authors.lastname: Al-Kattan
authors.forename: M
authors.initials: M
authors.lastname: Ashour
authors.forename: W
authors.initials: W
authors.lastname: Hajjar
authors.forename: M
authors.initials: M
authors.lastname: Salah El Din
authors.forename: M
authors.initials: M
authors.lastname: Fouda
authors.forename: A
authors.initials: A
authors.lastname: Al Bakry
mesh_terms: D000328:Adult; D000368:Aged; D001228:Aspergillosis / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000000981:diagnostic imaging / Q000601:surgery*; D009894:Opportunistic Infections / Q000000981:diagnostic imaging / Q000601:surgery*; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000601:surgery; D012086:Reoperation; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging / Q000601:surgery*