[Blood-eye barrier in the acute period of experimental severe alkaline burn of the eye by injection of deoxyglucose into the central vein].
The permeability of the blood-eye barrier for 14C-labeled deoxyglucose injected intravenously was studied on a model of severe experimental eye burn in 12 rabbits (24 eyes). The barrier permeability was evaluated by the content of radioactive material in the burnt eye humor in comparison with intact eye. Analysis of radiometric data showed a significant difference in the content of 14C in damaged and intact eyes. The permeability of the blood-eye barrier was increased in the damaged eye, this permeability depending on the concentration of the agent in the blood.
Kucherenko
L V
LV
D000208:Acute Disease; D000468:Alkalies / Q000493:pharmacokinetics; D000818:Animals; D002057:Burns, Chemical / Q000503:physiopathology*; D002199:Capillary Permeability; D002250:Carbon Radioisotopes; D003847:Deoxyglucose / Q000008:administration & dosage*; D005126:Eye Burns / Q000503:physiopathology*; D007275:Injections, Intravenous; D011817:Rabbits; D013997:Time Factors
D000468:Alkalies; D002250:Carbon Radioisotopes; D003847:Deoxyglucose