Cancer risk associated with residential proximity to industrial sites: a review.
In this study, the authors sought to review available epidemiologic studies of cancer risk and its association with residence in a neighborhood characterized by industrial sites and to discuss options for future study design. The authors attempted to identify all case-control studies published from January 1980 through July 1997 in which investigators examined exposure resulting from residential proximity to an industrial site neighborhood relative to an increased risk of lung, urinary tract, and lymphohematopoietic malignancies. During these years, some authors reported significant associations between lung cancer risk and residential proximity to (a) smelters, (b) complex industrial areas, and (c) other localized emission sources. There was some evidence that leukemia and lymphomas occurred in the neighborhoods that contained industrial sites.
Benedetti
M
M
National Institute of Health (ISS), Rome, Italy.
Iavarone
I
I
Comba
P
P
Lavarone
I
I
D015982:Bias; D016022:Case-Control Studies; D015984:Causality; D002985:Clinical Protocols / Q000592:standards; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D004784:Environmental Monitoring; D015340:Epidemiologic Research Design; D016021:Epidemiologic Studies; D062665:Epidemiological Monitoring; D019337:Hematologic Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D007221:Industry / Q000706:statistics & numerical data*; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D008223:Lymphoma / Q000453:epidemiology* / Q000209:etiology*; D008669:Metallurgy; D015203:Reproducibility of Results; D012111:Residence Characteristics / Q000706:statistics & numerical data*; D012680:Sensitivity and Specificity; D014571:Urologic Neoplasms / Q000453:epidemiology* / Q000209:etiology*