LTP gets culture.
In a recent breakthrough, a methodology has been developed for studying persistent enhancement of excitatory synaptic transmission in primary cultures of hippocampus. Results from the use of this method have already pointed to a previously unsuspected differential role for synaptic versus extrasynaptic NMDA receptors in lasting synaptic potentiation.
Salter
M W
MW
Programmes in Brain and Behaviour and Cell Biology, Hospital for Sick Children, Toronto, Canada. mike.salter@utoronto.ca
D000818:Animals; D002478:Cells, Cultured; D006624:Hippocampus / Q000166:cytology* / Q000502:physiology*; D017774:Long-Term Potentiation / Q000502:physiology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology
D016194:Receptors, N-Methyl-D-Aspartate