title: Impact of bulk cardiac motion on right coronary MR angiography and vessel wall imaging.
abstract: The purpose of this study was to investigate the impact of in-plane coronary artery motion on coronary magnetic resonance angiography (MRA) and coronary MR vessel wall imaging. Free-breathing, navigator-gated, 3D-segmented k-space turbo field echo ((TFE)/echo-planar imaging (EPI)) coronary MRA and 2D fast spin-echo coronary vessel wall imaging of the right coronary artery (RCA) were performed in 15 healthy adult subjects. Images were acquired at two different diastolic time periods in each subject: 1) during a subject-specific diastasis period (in-plane velocity <4 cm/second) identified from analysis of in-plane coronary artery motion, and 2) using a diastolic trigger delay based on a previously implemented heart-rate-dependent empirical formula. RCA vessel wall imaging was only feasible with subject-specific middiastolic acquisition, while the coronary wall could not be identified with the heart-rate-dependent formula. For coronary MRA, RCA border definition was improved by 13% (P < 0.001) with the use of subject-specific trigger delay (vs. heart-rate-dependent delay). Subject-specific middiastolic image acquisition improves 3D TFE/EPI coronary MRA, and is critical for RCA vessel wall imaging.
authors.affiliation: Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave., Boston, MA 02215, USA.
authors.forename: W Y
authors.initials: WY
authors.lastname: Kim
authors.forename: M
authors.initials: M
authors.lastname: Stuber
authors.forename: K V
authors.initials: KV
authors.lastname: Kissinger
authors.forename: N T
authors.initials: NT
authors.lastname: Andersen
authors.forename: W J
authors.initials: WJ
authors.lastname: Manning
authors.forename: R M
authors.initials: RM
authors.lastname: Botnar
mesh_terms: D000328:Adult; D017023:Coronary Angiography / Q000379:methods*; D003331:Coronary Vessels / Q000033:anatomy & histology* / Q000502:physiology; D003971:Diastole / Q000502:physiology; D017352:Echo-Planar Imaging; D005260:Female; D006321:Heart / Q000502:physiology*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged