Bladder wall dosimetry for 131I administered activities.
Detailed dosimetric calculations of bladder dose from 131I accumulations are presented, using Monte Carlo simulations and the dynamic bladder model proposed in the recent revision of MIRD Pamphlet No 14. Penetrating radiation and electron dose to the bladder wall inner surface, as well as within the bladder wall, per unit of 131I activity accumulated in the bladder, are calculated for various bladder filling volumes. The effect of backscatter was taken into account for photon dose calculations while electron dose was determined for all the beta spectral components of 131I. Dosimetric results were used to derive simple parameterisation functions of photon and electron dose with respect to bladder filling volume in combination with any bladder physiology model. Calculations of bladder dose per unit of 131I-OIH and 131I-NaI administered activity, using the derived parametrisations, differ by less than 12% from corresponding results given in the recent revision of MIRD Pamphlet No 14.
Likoka
E
E
Physics Department, University of Athens, Ilisia, Greece.
Angelopoulos
A
A
Baras
P
P
Karaiskos
P
P
Pantelis
E
E
Sakelliou
L
L
Dimitriou
P
P
D003198:Computer Simulation; D004583:Electrons; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D008962:Models, Theoretical; D009010:Monte Carlo Method; D017785:Photons; D011874:Radiometry; D012542:Scattering, Radiation; D001743:Urinary Bladder / Q000528:radiation effects*; D014599:Uterus / Q000528:radiation effects
D007457:Iodine Radioisotopes