Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei.
The indolopyridoquinazoline alkaloid, 3-hydoxyrutaecarpine, was isolated from Leptothyrsa sprucei, along with 8-methoxypsoralen, 5-methoxypsoralen, imperatorin, isoimperatorin, kaempferol 3-O-alpha-L-rhamnopyranoside, clematine and cnidioside B. The usefulness of the gradient 1H-15N HMBC NMR spectroscopy in the structure elucidation of 3-hydroxyrutaecarpine is noted.
Li
X C
XC
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS, USA.
Dunbar
D C
DC
ElSohly
H N
HN
Walker
L A
LA
Clark
A M
AM
D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D011799:Quinazolines / Q000737:chemistry / Q000302:isolation & purification*; D027821:Rutaceae / Q000737:chemistry*; D013057:Spectrum Analysis
C442179:3-hydoxyrutaecarpine; D007211:Indoles; D011799:Quinazolines