title: Sarcoidosis with giant parotomegaly.
abstract: We report the case of a 63-year-old man with bilateral parotid gland sarcoidosis. Giant, elastic, hard, subcutaneous tumors had been present on the right parotic and submaxillary regions for 11 years and on the left for 1 year. The patient had had diabetes mellitus for 8 years. Noncaseating epithelioid cell granulomata were revealed histopathologically in the periductal area of the parotid gland. Bilateral hilar lymphadenopathy was noted on chest x-ray studies. Serum levels of lysozyme were increased. Levels of serum angiotensin-converting enzyme were within normal limits. Tuberculin skin reaction was positive. The tumors gradually improved after treatment with oral minocycline. Giant parotomegaly, as it occurred in this case, is very rare.
authors.affiliation: Department of Dermatology, Dokkyo University School of Medicine, Mibu, Tochigi, 321-02, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ohtsuka
authors.forename: A
authors.initials: A
authors.lastname: Yanadori
authors.forename: H
authors.initials: H
authors.lastname: Tabata
authors.forename: A
authors.initials: A
authors.lastname: Yamakage
authors.forename: S
authors.initials: S
authors.lastname: Yamazaki
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000150:complications* / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology; D013363:Submandibular Gland / Q000473:pathology