[A case of transitional cell carcinoma of the urinary bladder with high serum level of CEA and CA19-9].
An 85-year-old male with asymptomatic gross hematuria was diagnosed with invasive bladder tumor, transitional cell carcinoma grade 3. Serum levels of CEA and CA19-9 were elevated and histological examination revealed expression of both markers in the cytoplasm of cancer cells. Out of therapeutic options, intra-arterial chemotherapy and radiotherapy were selected because of his age. During the treatment, serum levels of CEA and CA19-9 decreased along with reduction of tumor size. These serum markers have been reported to be elevated in 10 to 60% of patients with bladder tumor and are useful markers for evaluation of the treatment as suggested in the present case.
Inai
H
H
Department of Urology, Institute of Clinical Medicine, University of Tsukuba.
Shimazui
T
T
Yamamoto
T
T
Yamauchi
A
A
Uchida
K
K
Takeshima
H
H
Akaza
H
H
D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000097:blood*; D018395:CA-19-9 Antigen / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood*; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D006801:Humans; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000276:immunology*
D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen