title: Uterine perfusion and hormonal pattern in patients with polycystic ovary syndrome.
abstract: OBJECTIVE
  To evaluate whether polycystic ovary syndrome (PCOS) patients with different pulsatility index (PI) of uterine artery showed differences in their hormonal pattern.
  
  
  METHODS
  Eighty-eight PCOS-affected patients and 15 controls were submitted to Doppler flow measurement of uterine artery; LH, FSH PRL, estradiol, and androgens concentration determination; and BMI evaluation during early follicular phase.
  
  
  RESULTS
  The mean PI of uterine artery of PCOS patients was significantly higher than control group (2.97 +/- 0.9 vs. 1.89 +/- 0.2 respectively). The distribution of the PI'values was significantly different in the PCOS-affected patients and in control group. The plasma levels of DHEAS and BMI were significantly higher in PCOS patients with PI > or = 3 than in PCOS patients with PI < 3.
  
  
  CONCLUSIONS
  High resistance in the uterine artery is present in PCOS patients, but a wide range PI values of uterine artery is present. BMI and DHEAS seem to be factors interfering with uterine perfusion.
authors.affiliation: Department of Obstetrics and Gynecology, University of Cagliari, Ospedale San Giovanni di Dio, Via Ospedale 46, 09124, Cagliari, Italy. gimeli@tin.it
authors.forename: S
authors.initials: S
authors.lastname: Ajossa
authors.forename: S
authors.initials: S
authors.lastname: Guerriero
authors.forename: A M
authors.initials: AM
authors.lastname: Paoletti
authors.forename: M
authors.initials: M
authors.lastname: Orrù
authors.forename: S
authors.initials: S
authors.lastname: Floris
authors.forename: M
authors.initials: M
authors.lastname: Mannias
authors.forename: G B
authors.initials: GB
authors.lastname: Melis
mesh_terms: D000328:Adult; D000728:Androgens / Q000097:blood; D001158:Arteries / Q000502:physiology; D001835:Body Weight; D016022:Case-Control Studies; D003687:Dehydroepiandrosterone / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D011085:Polycystic Ovary Syndrome / Q000378:metabolism* / Q000503:physiopathology*; D011388:Prolactin / Q000097:blood; D012039:Regional Blood Flow; D014599:Uterus / Q000098:blood supply*
chemical_list: D000728:Androgens; D006728:Hormones; D003687:Dehydroepiandrosterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone