The action of mercury on cell membranes.
The action of mercuric chloride and methyl mercuric chloride on the membrane lateral domain organization of bovine, equine, and canine erythrocytes was studied. Electron paramagnetic resonance (EPR) spectra of spin-labeled erythrocytes were analyzed with respect to their lateral domain structure. Continuous alteration of the membrane domain populations revealed that mercuric compounds affect the membrane via the evolution of toxic events in the cells.
Schara
M
M
J. Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.
Nemec
M
M
Falnoga
I
I
Kobal
A B
AB
Kveder
M
M
Svetek
J
J
D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000187:drug effects*; D004285:Dogs; D004578:Electron Spin Resonance Spectroscopy; D004912:Erythrocytes / Q000378:metabolism; D006736:Horses; D008627:Mercuric Chloride / Q000494:pharmacology*; D008767:Methylmercury Compounds / Q000494:pharmacology*; D017434:Protein Structure, Tertiary; D013045:Species Specificity; D013997:Time Factors
D008767:Methylmercury Compounds; D008627:Mercuric Chloride; C004925:methylmercuric chloride