[Effect of low doses of low-intensity irradiation on the incidence and progress of spontaneous leukosis in AKR mice].
Development of spontaneous leukosis in AKR mice is accelerated by irradiation with low doses (1.2-2.4 cGy, dose-rate 0.6 cGy/day): the leukoses incidence rate increases, deaths of the animals from leukosis occurs earlier, shortening the average and maximum life-spans of the animals. The dynamics of changes in the mass of organs of the immune systems (thymus and spleen) shown extrema. The moment of reaching the extremum correlates with the maximum rate of animals' deaths.
Burlakova
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EB
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, 119991 Russia. chembio@glas.aps.org
Erokhin
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VN
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D007953:Leukemia, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D051379:Mice; D008806:Mice, Inbred AKR; D013154:Spleen / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology
Vliianie nizkointensivnogo oblucheniia v malykh dozakh na vozniknovenie i razvitie spontannogo leĭkoza u mysheĭ linii AKR.