Galli-Galli disease: an unrecognized entity or an acantholytic variant of Dowling-Degos disease?
Galli-Galli disease is an inherited disease characterized by slowly progressive and disfiguring reticulate hyperpigmentation of the flexures, clinically and histopathologically diagnostic for Dowling-Degos disease, but also associated with suprabasal, nondyskeratotic acantholysis. A few patients exhibiting these features have been described, mainly in the non-English-language literature, which suggests that Galli-Galli disease is not an entity of its own, as originally thought, but is an acantholytic variant of Dowling-Degos disease. We report a typical case of Galli-Galli disease, which supports this concept.
Braun-Falco
M
M
Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München, Biedersteinerstrasse 29, 80802 Munich, Germany. mbf@krz.tum.de
Volgger
W
W
Borelli
S
S
Ring
J
J
Disch
R
R
D000051:Acantholysis / Q000175:diagnosis / Q000473:pathology*; D003872:Dermatitis / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000473:pathology; D010859:Pigmentation Disorders / Q000175:diagnosis / Q000473:pathology*