The fight against smallpox in Japan.  The value of western medicine proved.
Beukers
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D000486:Allergy and Immunology / Q000266:history*; D049690:History, Ancient; D049692:History, Early Modern 1451-1600; D049691:History, Medieval; D049711:History, Modern 1601-; D007564:Japan; D009426:Netherlands; D012899:Smallpox / Q000266:history*