Peroxisome proliferator-activated receptor (PPAR) modulators: diabetes and beyond.
Peroxisome proliferator-activated receptors (PPARs) are a class of ligand modulated transcription factors with a prominent role in the regulation of metabolic processes. This report is intended to provide a limited introduction to the PPAR field, sketched with reference to one early series of PPAR ligands.
Jones
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Department of Basic Chemistry, Merck Research Laboratories, Merck & Co. Inc. P.O. Box 2000, Rahway, New Jersey 07065, USA. brian_jones@merck.com
D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism*; D006801:Humans; D018160:Receptors, Cytoplasmic and Nuclear / Q000187:drug effects*; D014157:Transcription Factors / Q000187:drug effects*
D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors