Radiation-associated valvular heart disease in Hodgkin's disease is associated with characteristic thickening and fibrosis of the aortic-mitral curtain.
Radiation-associated valvular dysfunction is characterized by variable aortic and mitral valve thickening. A review of three patients assessed echocardiographically revealed that radiation-associated valvular dysfunction after radiation treatment for Hodgkin's disease may be characterized by a unique and consistent pattern of thickening of the aortic and mitral valves involving the aortic-mitral curtain.
Brand
M D
MD
Cardiovascular Division, University of Massachusetts-Memorial Medical Center and University of Massachusetts Medical School, Worcester 01655, USA.
Abadi
C A
CA
Aurigemma
G P
GP
Dauerman
H L
HL
Meyer
T E
TE
D001021:Aortic Valve / Q000528:radiation effects*; D005260:Female; D006349:Heart Valve Diseases / Q000209:etiology* / Q000401:mortality; D006689:Hodgkin Disease / Q000150:complications* / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000528:radiation effects*; D017564:Radiation Pneumonitis / Q000150:complications* / Q000401:mortality; D017211:Treatment Failure