[Cortical connectivity in schizophrenic patients with positive and negative symptoms ].
The paper is dedicated to the problem of disturbed "connectivity" between different cortical areas in schizophrenic patients with the dominance of "negative" and "positive" symptoms. The architecture of cortical connections in high-frequency range of the beta rhythm (beta 2, 20-40 Hz) was studied in three groups of right-handed men: healthy control group (16 subjects) and schizophrenic patients with the dominance of positive (16 subjects) and negative (22 subjects) symptoms assessed by the SAPS and SANS scales. Two versions of the Intracortical Interaction Mapping (IIM) technique of examination of cortical connections were used. In the 1st version, mean connection frequencies in the beta 2-rhythm for each group were analyzed. In the 2nd version, the most typical for a given group connection frequencies were studied. Additionally, since the IIM technique is rather new, coherence function in the beta 2-rhythm calculated by the standard way was also taken into account. The obtained results made it possible to reveal the derangements in the system of cortical interactions in schizophrenic patients.
Strelets
V B
VB
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.
Novototskiĭ-Vlasov
V Iu
VIu
Golikova
Zh V
ZhV
D001611:Beta Rhythm; D001931:Brain Mapping; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology
Korkovye sviazi u bol'nykh shizofrenieĭ s pozitivnymi i negativnymi simptomami.