Treatment strategy and perioperative risk in patients with idiopathic thrombocytopenic purpura undergoing cardiac surgery.
Patients suffering from idiopathic thrombocytopenic purpura undergoing cardiac surgery with extracorporeal circulation may be at increased risk for postoperative bleeding complications. Therefore, different treatment strategies, such as conservative treatment, splenectomy, transfusion of platelet concentrates and therapy with immunoglobulins have been proposed. We report on our experiences with preoperative immunoglobulin treatment in selected patients with special regard on the optimal dosage.
Christiansen
S
S
Department of Cardiothoracic Surgery, Westfälische Wilhelms-Universität, Albert-Schweitzer-Strasse 33, 48149 Münster, Germany. stefan.christiansen@thgms.uni-muenster.de
Redmann
K
K
Schmid
C
C
Scheld
H H
HH
D000368:Aged; D006348:Cardiac Surgical Procedures; D000075202:Contraindications; D005112:Extracorporeal Circulation; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care; D010976:Platelet Count; D011300:Preoperative Care; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000150:complications*; D012307:Risk Factors