title: Radiation-associated valvular heart disease in Hodgkin's disease is associated with characteristic thickening and fibrosis of the aortic-mitral curtain.
abstract: Radiation-associated valvular dysfunction is characterized by variable aortic and mitral valve thickening. A review of three patients assessed echocardiographically revealed that radiation-associated valvular dysfunction after radiation treatment for Hodgkin's disease may be characterized by a unique and consistent pattern of thickening of the aortic and mitral valves involving the aortic-mitral curtain.
authors.affiliation: Cardiovascular Division, University of Massachusetts-Memorial Medical Center and University of Massachusetts Medical School, Worcester 01655, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: Brand
authors.forename: C A
authors.initials: CA
authors.lastname: Abadi
authors.forename: G P
authors.initials: GP
authors.lastname: Aurigemma
authors.forename: H L
authors.initials: HL
authors.lastname: Dauerman
authors.forename: T E
authors.initials: TE
authors.lastname: Meyer
mesh_terms: D001021:Aortic Valve / Q000528:radiation effects*; D005260:Female; D006349:Heart Valve Diseases / Q000209:etiology* / Q000401:mortality; D006689:Hodgkin Disease / Q000150:complications* / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000528:radiation effects*; D017564:Radiation Pneumonitis / Q000150:complications* / Q000401:mortality; D017211:Treatment Failure