Diastolic function in hypertension.
Diastolic dysfunction in patients with hypertension may present as asymptomatic findings on noninvasive testing, or as fulminant pulmonary edema, despite normal left ventricular systolic function. Up to 40% of hypertensive patients presenting with clinical signs of congestive heart failure have normal systolic left ventricular function. In this article we review the pathophysiologic factors affecting diastolic function in individuals with diastolic function, current and emerging tools for measuring diastolic function, and current concepts regarding the treatment of patients with diastolic congestive heart failure.
Phillips
R A
RA
Department of Medicine, Lenox Hill Hospital, 100 East 77th Street, New York, NY 10021, USA. rphillips@lenoxhill.net
Diamond
J A
JA
D001794:Blood Pressure / Q000502:physiology*; D006333:Heart Failure / Q000209:etiology / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology* / Q000628:therapy; D012307:Risk Factors; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000628:therapy; D016277:Ventricular Function, Left / Q000502:physiology*