title: Antimicrobial susceptibilities of 1,730 Haemophilus influenzae respiratory tract isolates in Spain in 1998-1999.
abstract: A beta-lactamase prevalence of 23% was found among 1,730 Haemophilus influenzae isolates. Ampicillin susceptibility was 70%, and 12% of beta-lactamase-negative strains presented diminished susceptibility to ampicillin (BLNAR phenotype). Susceptibility of 90% was found for cefaclor and clarithromycin, whereas it was nearly 100% for cefotaxime, cefixime, azithromycin, and cefuroxime. Ciprofloxacin-resistant (0.1%) and beta-lactamase-positive amoxicillin/clavulanate-resistant (BLPACR) phenotypes (0.1%) are anecdotal so far.
authors.affiliation: Microbiology Department, IDIBAPS, Hospital Cliníc, Barcelona, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Marco
authors.forename: J
authors.initials: J
authors.lastname: García-de-Lomas
authors.forename: C
authors.initials: C
authors.lastname: García-Rey
authors.forename: E
authors.initials: E
authors.lastname: Bouza
authors.forename: L
authors.initials: L
authors.lastname: Aguilar
authors.forename: C
authors.initials: C
authors.lastname: Fernández-Mazarrasa
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D006192:Haemophilus Infections / Q000382:microbiology; D006193:Haemophilus influenzae / Q000187:drug effects* / Q000201:enzymology; D008826:Microbial Sensitivity Tests; D010641:Phenotype; D012141:Respiratory Tract Infections / Q000382:microbiology*; D013030:Spain; D001618:beta-Lactamases / Q000096:biosynthesis
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D001618:beta-Lactamases