[Relationship between dyspnea and quality of life with body mass index and pulmonary function in patients with chronic obstructive airways disease and emphysema].
BACKGROUND
We aimed to evaluate the differences in pulmonary function, quality of life (CVRS) and dyspnea in patients with chronic obstructive pulmonary disese (COPD) and emphysema according to the body mass index (BMI). Moreover, we analyzed the relation between BMI, pulmonary function, CVRS and dyspnea.


METHODS
This was a prospective, 12-months study including 20 patients with COPD and emphysema. They were classified in group A (BMI < 21 kg/m(2) group B (BMI >= 21 kg/m(2)). We performed pulmonary function tests and determined the levels of dyspnea and CVRS according to a scale of dyspnea and a CVRS questionnaire.


RESULTS
Seven patients had a BMI < 21 kg/m(2) and it was >=21 kg/m(2) in 13 patients. DLCO in group A patients was lower than in group B. After a multiple regression analysis, the FVC accounted for 52% of dyspnea variability. Both PEM and dyspnea were the parameters that better predicted the CVRS.


CONCLUSIONS
Patients with COPD and emphysema with a VMI < 21 kg/m(2) have a lower DLCO than patients with a BMI >= 21 kg/m(2). In our patients, dyspnea sensation depended on the FVC. In addition,the CVRS depended on dyspnea sensation and PEM.
González Constán
E
E
Servicio de Neumología. Hospital Universitario Dr. Peset. Valencia.
Herrejón Silvestre
A
A
Inchaurraga Alvarez
I
I
Palop Medina
J
J
Blanquer Olivas
R
R
D000368:Aged; D015992:Body Mass Index; D004417:Dyspnea / Q000209:etiology*; D004646:Emphysema / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D011788:Quality of Life; D012119:Respiration
Relación de la disnea y la calidad de vida con el índice de masa corporal y la función pulmonar en pacientes con enfermedad pulmonar obstructiva crónica tipo enfisema.