title: Synthesis of cis- and trans-5,8-dihydroxy-5,6,7,8-tetrahydro-1,4-naphthoquinone.
abstract: Cis- and trans-5,8-dihydroxy-5,6,7,8-tetrahydro-1,4-naphthoquinone (1a, 1b) were for the first time synthesized from 5,8-dihydroxy-1,4-naphthoquinone (naphthazazine) (6) as a starting material and racemic triol (3) was first synthesized from 7. The configuration of 1a was determined by X-ray analysis.
authors.affiliation: School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan. arimas@pharm.kitasato-u.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Arima
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada Konda
authors.forename: K
authors.initials: K
authors.lastname: Takeda
authors.forename: H
authors.initials: H
authors.lastname: Takayanagi
authors.forename: Y
authors.initials: Y
authors.lastname: Harigaya
mesh_terms: D018360:Crystallography, X-Ray; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D008958:Models, Molecular; D009285:Naphthoquinones / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: C450641:5,8-dihydroxy-5,6,7,8-tetrahydro-1,4-naphthoquinone; D007202:Indicators and Reagents; D009285:Naphthoquinones