Equine rhinitis B virus: a new serotype.
Equine rhinovirus serotype 3 isolate P313/75 was assigned, with an unclassified genus status, to the family PICORNAVIRIDAE: The sequence from the 5' poly(C) tract to the 3' poly(A) tract of P313/75 was determined. The sequence is 8821 bases in length and contains a potential open reading frame for a polyprotein of 2583 amino acids. Sequence comparison and phylogenic analysis suggest that P313/75 is most closely related to the prototype equine rhinitis B virus (ERBV) strain P1436/71, formerly named equine rhinovirus type 2. A high degree of sequence similarity was found in the P2 and P3 regions of the two genomes. However, the deduced amino acid sequences of the P1 region of P313/75 and ERBV strain P1436/71 contained significant differences, which presumably account for the serological segregation of the two viruses. It is suggested that P313/75 can be classified as a new serotype of the genus Erbovirus, tentatively named ERBV2. Seroepidemiological data indicate that ERBV2 infection of horses may be common (24%) in Australia.
Huang
Jin-An
JA
Centre for Equine Virology, School of Veterinary Science, The University of Melbourne, Victoria 3010, Australia1.
Ficorilli
Nino
N
Centre for Equine Virology, School of Veterinary Science, The University of Melbourne, Victoria 3010, Australia1.
Hartley
Carol A
CA
Centre for Equine Virology, School of Veterinary Science, The University of Melbourne, Victoria 3010, Australia1.
Wilcox
Rebbecca S
RS
Centre for Equine Virology, School of Veterinary Science, The University of Melbourne, Victoria 3010, Australia1.
Weiss
Marianne
M
Institute of Veterinary Virology, University of Berne, Berne, Switzerland2.
Studdert
Michael J
MJ
Centre for Equine Virology, School of Veterinary Science, The University of Melbourne, Victoria 3010, Australia1.
D000595:Amino Acid Sequence; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D005537:Aphthovirus / Q000737:chemistry / Q000145:classification* / Q000235:genetics; D001315:Australia / Q000453:epidemiology; D006734:Horse Diseases / Q000453:epidemiology / Q000821:virology*; D006736:Horses; D008969:Molecular Sequence Data; D010850:Picornaviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D011061:Poly A; D011066:Poly C; D017422:Sequence Analysis, DNA; D012703:Serotyping
D000914:Antibodies, Viral; D011061:Poly A; D011066:Poly C