title: Occupational exposure to endocrine-disrupting pesticides and the potential for developing hormonal cancers.
abstract: It is suspected that endocrine-disrupting pesticides are involved in the development of several cancer and noncancer health risks in humans and wildlife. A large number of pesticides show endocrine-disrupting activities. The potential for human and animal exposure to such pesticides is very high. Farmers, as a group, may be particularly at risk, because they are subject to higher-than-average levels of exposure to pesticides over longer-than-average periods. Recent studies have shown that the incidence of hormone-related organ cancers, or hormonal cancers, is elevated among farmers. Exposure to endocrine-disrupting pesticides, particularly to DDT and phenoxy herbicides, is suspected of involvement in some of these hormonal cancers. There is a clear need for a refined epidemiological study that focuses on specific pesticides, accurately assesses exposure, and then examines any association between pesticides and hormonal cancers among farmers.
authors.affiliation: Department of Environmental Health Sciences, 1667 University Blvd., Ryals Building #309E, University of Alabama, Birmingham, AL 35294-0022, USA.
authors.forename: S
authors.initials: S
authors.lastname: Buranatrevedh
authors.forename: D
authors.initials: D
authors.lastname: Roy
mesh_terms: D000383:Agriculture; D001943:Breast Neoplasms / Q000209:etiology*; D004701:Endocrine Gland Neoplasms / Q000209:etiology*; D004703:Endocrine System / Q000187:drug effects*; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D008297:Male; D016273:Occupational Exposure; D009790:Occupations; D010575:Pesticides / Q000009:adverse effects*; D018570:Risk Assessment
chemical_list: D010575:Pesticides