title: Fatal overdose with trazodone: case report and literature review.
abstract: A fatal case of suicide with trazodone alone in a 40-year-old patient is reported. Life-threatening arrhythmias, such as torsades de pointes and complete AV block, are recorded. Blood collected at admission contained a trazodone toxic concentration of 25.4 micrograms/mL. The patient developed multiple organ failure and died less than 24 hours after his admission to the emergency department. The authors discuss the effects of overdose of trazodone, a well-known safe antidepressant drug.
authors.affiliation: Cardiology Department, Jolimont Hospital, 7100 Haine Saint Paul, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: de Meester
authors.forename: G
authors.initials: G
authors.lastname: Carbutti
authors.forename: L
authors.initials: L
authors.lastname: Gabriel
authors.forename: J M
authors.initials: JM
authors.lastname: Jacques
mesh_terms: D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000506:poisoning*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D004562:Electrocardiography; D006801:Humans; D008297:Male; D013405:Suicide; D014196:Trazodone / Q000506:poisoning*
chemical_list: D018687:Antidepressive Agents, Second-Generation; D014196:Trazodone