title: Synthesis and antimycobacterial activity of [5-(pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives.
abstract: [5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed a feable activity against a strain of Mycobacterium tuberculosis and a strain of Mycobacterium avium.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università, di Trieste, Italy. mamolo@univ.trieste.it
authors.forename: M G
authors.initials: MG
authors.lastname: Mamolo
authors.forename: V
authors.initials: V
authors.lastname: Falagiani
authors.forename: D
authors.initials: D
authors.lastname: Zampieri
authors.forename: L
authors.initials: L
authors.lastname: Vio
authors.forename: E
authors.initials: E
authors.lastname: Banfi
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects; D013329:Structure-Activity Relationship; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D013830:Thiadiazoles