title: The measurement of three dimensional dose distribution of a ruthenium-106 ophthalmological applicator using magnetic resonance imaging of BANG polymer gels.
abstract: The BANG (MGS Research Inc., Guilford, CT) polymer gel has been used as a dosimeter to determine the three-dimensional (3D) dose distribution of a ruthenium-106 (Ru-106) ophthalmologic applicator. An eye phantom made of the BANG gel was irradiated with the Ru-106 source for up to 1 h. The phantom and a set of calibration vials were scanned simultaneously in a GE 1.5 T MR imager using the Hahn spin-echo pulse sequence with a TR of 2000 ms and two TEs of 20 ms and 100 ms. The T(2) values were evaluated on a pixel-by-pixel basis using custom-built software on a DEC alpha workstation and converted to dose using calibration data. Depth doses and isodose lines of the Ru-106 eye-plaque were generated. It is concluded that the BANG gel dosimetry offers the potential for measuring the 3D dose distributions of an ophthalmologic applicator, with high spatial resolution and relatively good accuracy.
authors.affiliation: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, New York 10021, USA. chanm@mskcc.org
authors.forename: M F
authors.initials: MF
authors.lastname: Chan
authors.forename: A Y
authors.initials: AY
authors.lastname: Fung
authors.forename: Y C
authors.initials: YC
authors.lastname: Hu
authors.forename: C S
authors.initials: CS
authors.lastname: Chui
authors.forename: H
authors.initials: H
authors.lastname: Amols
authors.forename: M
authors.initials: M
authors.lastname: Zaider
authors.forename: D
authors.initials: D
authors.lastname: Abramson
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D005134:Eye Neoplasms / Q000532:radiotherapy*; D005782:Gels; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008545:Melanoma / Q000532:radiotherapy*; D019047:Phantoms, Imaging; D011108:Polymers; D011834:Radiation Monitoring / Q000295:instrumentation*; D019572:Retinal Neoplasms / Q000532:radiotherapy; D012175:Retinoblastoma / Q000532:radiotherapy; D012429:Ruthenium Radioisotopes
chemical_list: C106521:BANG polymer gel; D005782:Gels; D011108:Polymers; D012429:Ruthenium Radioisotopes