title: Uses and complications of isotretinoin therapy.
abstract: Isotretinoin (13-cis-retinoic acid) is a retinoid that has been used over the past 2 decades to treat a wide variety of dermatologic conditions, some with great success. Although it is beneficial in many skin conditions, the side effects and toxicities of oral retinoids require careful monitoring by experienced physicians. The clinical applications of oral retinoids continue to expand both within and beyond the field of dermatology.
authors.affiliation: Department of Dermatology, 1910 A Alfred Taubman Center, University of Michigan Medical School, Ann Arbor, MI 48109-0314, USA. cellis@umich.edu
authors.forename: C N
authors.initials: CN
authors.lastname: Ellis
authors.forename: K J
authors.initials: KJ
authors.lastname: Krach
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000375:Aging; D003879:Dermatologic Agents / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D015474:Isotretinoin / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy; D012871:Skin Diseases / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000517:prevention & control
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin