title: [Pulsatile rotary pumps with low hemolysis].
abstract: As is well known, a pulsatile flow is important in assisted-circulation but it is difficult to produce a pulsatile flow with rotary pump, because excessive hemolysis will be generated. The authors have found that the turbulent shear is the main factor for red cell damage and therefore the key point of pulsatile rotary pumps is to reduce the turbulence by producing a pulsatile flow. In the authors' pulsatile axial pump, the pulsatile flow is obtained by axial reciprocation of constant rotating impeller; the rotation and reciprocation of the impeller are driven separately by a DC motor and a pneumatic device. Though a physiological pulsatile flow could be achieved and turbulence would not increase remarkably because the impeller rotates constantly, a second driver except a DC motor is nevertheless necessary, thus the system will become complicated. In the authors' pulsatile radial pump, a pulsatile flow is achieved by changing the rotating speed of the impeller periodically. Turbulence is minimized by a special design of twisted vanes which enable the blood flow to change its direction rather than its dimension during periodic change of rotating speed. Hemolysis tests demonstrated that the index of hemolysis(IH) of the author's pulsatile radial pump is 0.020, with is slightly more than that of the author's nonpulsatile radial pump(IH = 0.015). Animal experiments indicated that the pulsatile radial pump can assist the circulation of calves for several months without harm to blood elements and organ functions of the recipients.
authors.affiliation: Institute of Biomedical Engineering, Jiangsu University of Science & Technology, Zhenjiang 212013.
authors.forename: K
authors.initials: K
authors.lastname: Qian
authors.forename: P
authors.initials: P
authors.lastname: Zeng
authors.forename: W
authors.initials: W
authors.lastname: Ru
authors.forename: H
authors.initials: H
authors.lastname: Yuan
authors.forename: Z
authors.initials: Z
authors.lastname: Feng
authors.forename: L
authors.initials: L
authors.lastname: Li
mesh_terms: D000818:Animals; D002417:Cattle; D006353:Heart-Assist Devices; D006461:Hemolysis; D011673:Pulsatile Flow