title: [Endothelial dysfunction in the development of vascular complications in diabetes mellitus].
abstract: Patients with type 1 diabetes, aged 18 to 42 years, were compared to those aged 11 to 22 years. Activities of endothelial vasoactive factors and endothelial and leukocyte adhesion molecules were studied at different stages of development diabetes complications: nephropathy and retinopathy. The findings reveal role of the vasoactive factors in microangiopathy course.
authors.forename: I I
authors.initials: II
authors.lastname: Dedov
authors.forename: M V
authors.initials: MV
authors.lastname: Shestakov
authors.forename: T V
authors.initials: TV
authors.lastname: Kochemasova
authors.forename: I S
authors.initials: IS
authors.lastname: Severina
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Baryshnikov
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000032:analysis; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000378:metabolism*; D003928:Diabetic Nephropathies / Q000209:etiology / Q000378:metabolism*; D003930:Diabetic Retinopathy / Q000209:etiology / Q000378:metabolism*; D019040:E-Selectin / Q000378:metabolism; D019332:Endothelin-1 / Q000378:metabolism; D004730:Endothelium, Vascular / Q000378:metabolism*; D011464:Epoprostenol / Q000378:metabolism; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000378:metabolism; D008833:Microcirculation; D009569:Nitric Oxide / Q000378:metabolism; D013928:Thromboxane A2 / Q000378:metabolism
chemical_list: D015415:Biomarkers; D019040:E-Selectin; D019332:Endothelin-1; D018799:Intercellular Adhesion Molecule-1; D009569:Nitric Oxide; D013928:Thromboxane A2; D011464:Epoprostenol
vernacular_title: Disfunktsiia épiteliia v razvitii sosudistykh oslozhneniĭ sakharnogo diabeta (problemnaia stat'ia).