title: Primary pigmented malignant schwannoma in the posterior mediastinum.
abstract: This paper describes a rare case of primary pigmented malignant schwannoma arising from the sympathetic trunk in the posterior mediastinum. A 30-year-old woman underwent a thoracoscopic tumor extirpation. A primary pigmented malignant schwannoma was diagnosed histologically. The tumor presented fascicles and whorls of pigmented plump spindle cells and positive immunoreactivity to S-100 protein, vimentin, and HMB-45. Postoperative radiotherapy of the mediastinum was performed. Our case demonstrates the successful thoracoscopic resection and postoperative radiation treatment of a malignant schwannoma.
authors.affiliation: Department of Cardiothoracic Surgery, Westphalian Wilhelms University-Hospital of Munster, Albert-Schweitzer-Strasse 33, 48129 Munster, Germany. markus.rothenberger@thgms.uni-muenster.de
authors.forename: M
authors.initials: M
authors.lastname: Rothenburger
authors.forename: M
authors.initials: M
authors.lastname: Semik
authors.forename: C
authors.initials: C
authors.lastname: Schmidt
authors.forename: A
authors.initials: A
authors.lastname: Hoffmeier
authors.forename: C
authors.initials: C
authors.lastname: August
authors.forename: H H
authors.initials: HH
authors.lastname: Scheld
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D009442:Neurilemmoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D010858:Pigmentation