title: Diet and drug therapy: a dynamic duo for reducing coronary heart disease risk.
abstract: A large proportion of the United States population requires aggressive low-density lipoprotein (LDL) cholesterol- lowering therapy to meet the new treatment guidelines established by the National Cholesterol Education Program Adult Treatment Panel III. This has further widened the gap between the number of people being treated compared with those who should be treated. Moreover, many people being treated do not meet their LDL cholesterol goal. Diet and healthy lifestyle practices remain the cornerstone of treatment to lower LDL cholesterol. Pharmacologic therapy has assumed an increasingly important role in reaching LDL cholesterol goals. Diet and healthy-lifestyle interventions have been shown to augment the benefits of cholesterol-lowering drugs. Together, this dynamic duo provides the most effective clinical means identified to date for maximally lowering LDL cholesterol levels.
authors.affiliation: Nutrition Department, Pennsylvania State University, S126 Henderson Bldg., University Park, PA 16802, USA.
authors.forename: K F
authors.initials: KF
authors.lastname: Clemmer
authors.forename: A E
authors.initials: AE
authors.lastname: Binkoski
authors.forename: S M
authors.initials: SM
authors.lastname: Coval
authors.forename: G
authors.initials: G
authors.lastname: Zhao
authors.forename: P M
authors.initials: PM
authors.lastname: Kris-Etherton
mesh_terms: D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D008078:Cholesterol, LDL / Q000097:blood*; D003131:Combined Modality Therapy; D003327:Coronary Disease / Q000097:blood / Q000178:diet therapy* / Q000188:drug therapy* / Q000517:prevention & control; D005247:Feeding Behavior; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors