[The current situation and future of extracellular matrix materials for bone tissue engineering].
The requirements of ideal extracellular matrix materials for bone tissue engineering were stated, and the advantages and disadvantages of bioceramics, biodegradable synthetic polymers and natural polymers were analyzed. Based on these, we highlight a point that the ideal extracellular matrix materials for bone tissue engineering should be made up of bioceramics materials, synthetic polymers or natural polymers. These materials should possess a morphological structure of three-dimensional foam and have a self-mediated drug delivery system of bone growth factors. The design and manufacture of such compound extracellular matrix materials for bone tissue engineering is a very important and urgent challenge.
Zheng
L
L
Department of Laboratory Medicine, Nanfang Hospital, First Military Medical University, Guangzhou 510515.
Wang
Q
Q
D001672:Biocompatible Materials; D018786:Bone Substitutes; D002516:Ceramics; D005109:Extracellular Matrix; D011108:Polymers; D023822:Tissue Engineering
D001672:Biocompatible Materials; D018786:Bone Substitutes; D011108:Polymers