title: [Increased Neisseria gonorrhoeae quinolone resistance in Amsterdam].
abstract: In addition to a rise in the number of cases of gonorrhoea, the susceptibility of Neisseria gonorrhoeae to antibiotics is also a cause for concern. After a period of high resistance rates to penicillin and tetracycline between 1985 and 1995, resistance rates have dropped considerably in recent years, probably due to changes in treatment regimens. However, recently we have seen an increasing number of quinolone-resistant N. gonorrhoeae isolates in Amsterdam, the Netherlands, a development that has previously been reported in other parts of the world. Some form of national resistance monitoring for gonococci is therefore urgently required to allow timely detection of changes in N. gonorrhoeae resistance.
authors.affiliation: Afd. Streeklaboratorium voor de Volksgezondheid en Bijzonder Instituut voor de Virologie, Gemeentelijke Geneeskundige en Gezondheidsdienst (GG&GD), Nieuwe Achtergracht 100, 1018 WT Amsterdam. ppeerbooms@gggd.amsterdam.nl
authors.forename: P G
authors.initials: PG
authors.lastname: Peerbooms
authors.forename: J
authors.initials: J
authors.lastname: Spaargaren
authors.forename: J S
authors.initials: JS
authors.lastname: Fennema
authors.forename: I
authors.initials: I
authors.lastname: Cairo
authors.forename: R A
authors.initials: RA
authors.lastname: Coutinho
mesh_terms: D042462:4-Quinolones; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D006069:Gonorrhea / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000302:isolation & purification; D009426:Netherlands / Q000453:epidemiology; D015995:Prevalence
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents
vernacular_title: Toename van chinolonresistentie bij Neisseria gonorrhoeae in Amsterdam.