title: Continuous subcutaneous insulin infusion: a comprehensive review of insulin pump therapy.
abstract: A tremendous amount of data suggest that near-normal glycemic control prevents or delays complications of diabetes, which has led to a dramatic increase in continuous subcutaneous insulin infusion (CSII) or insulin pump use. In this article, the data supporting CSII in type 1 diabetes is reviewed, and the advantages and disadvantages of CSII are analyzed. In addition, CSII use in specific situations is examined, including during childhood and pregnancy and while exercising. The published articles suggest that CSII provides better glycemic control than does conventional therapy and comparable to or slightly better control than multiple daily injections. The use of CSII may be especially indicated during pregnancy or for preconception care and for diabetes presenting in childhood or adolescence.
authors.affiliation: Diabetes and Metabolic Diseases Center, Section of Endocrinology, Christiana Care Health Services, 700 Lea Blvd, Suite 300, Wilmington, DE 19802, USA. JLenhard@ChristianaCare.org
authors.forename: M J
authors.initials: MJ
authors.lastname: Lenhard
authors.forename: G D
authors.initials: GD
authors.lastname: Reeves
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D004867:Equipment Design; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007328:Insulin / Q000008:administration & dosage* / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D011247:Pregnancy
chemical_list: D007328:Insulin