title: [Effect of rotundine on gastric acid and pepsin activity in rats].
abstract: A test was made on the effect of rotundine on the secretion of gastric acid and pepsin activity in rats. Compared with the control group, rotundine(> or = 17.1 mg/kg) inhibited gastric acid and decreased secretion of gastric juice(P < 0.01), but had no influence on pepsin activity. There was a negative relationship between total acidity and pH of gastric juice (r = -0.9818).
authors.affiliation: Department of Clinical Pharmacy, Wuhan Central Railway Hospital, Wuhan 430064.
authors.forename: M
authors.initials: M
authors.lastname: Zhou
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: L
authors.initials: L
authors.lastname: Geng
authors.forename: C
authors.initials: C
authors.lastname: Qu
authors.forename: S
authors.initials: S
authors.lastname: Peng
mesh_terms: D000818:Animals; D001600:Berberine Alkaloids / Q000494:pharmacology*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D008297:Male; D010434:Pepsin A / Q000378:metabolism*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001600:Berberine Alkaloids; C014215:tetrahydropalmatine; D010434:Pepsin A