title: [Multidrug-resistant and fluoroquinolone-resistant Salmonella enterica serotype Typhimurium definitive phage type 12 isolated from infantile diarrhea].
abstract: A 35-day-old male infant was admitted to our hospital, presenting a high fever, vomiting, and diarrhea. Multidrug-resistant and fluoroquinolon-resistant Salmonella serotype Typhimurium was isolated from his stool. The phage type of the strain was DT12. The strain was resistant to ampicillin, streptomycin, gentamicin, tetracycline, chloramphenicol, sulfamethoxazole-trimethoprim, and fluoroquinolones (levofloxacin; MIC 8 micrograms/ml, norfloxacin; 24 micrograms/ml, ciprofloxacin; 16 micrograms/ml, sparfloxacin; 32 micrograms/ml). He was cured by antibiotic therapy using fosfomycin (< or = 1 microgram/ml). We could not determine a route of infection. Domestic surveillance for fluoroquinolon-resistant Sallmonella is necessary.
authors.affiliation: Department of Clinical Center Laboratory, Kansai Medical University.
authors.forename: H
authors.initials: H
authors.lastname: Nakaya
authors.forename: A
authors.initials: A
authors.lastname: Yasuhara
authors.forename: K
authors.initials: K
authors.lastname: Yoshimura
authors.forename: Y
authors.initials: Y
authors.lastname: Oshihoi
authors.forename: H
authors.initials: H
authors.lastname: Izumiya
authors.forename: H
authors.initials: H
authors.lastname: Watanabe
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D003968:Diarrhea, Infantile / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D024841:Fluoroquinolones; D006801:Humans; D007223:Infant; D008297:Male; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000302:isolation & purification*
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones