title: Evaluation of signal-averaged electrocardiography for clinical diagnosis in arrhythmogenic right ventricular dysplasia.
abstract: Arrhythmogenic right ventricular dysplasia (ARVD) is a heart muscle disorder of unknown etiology that is characterized pathologically by fibrofatty replacement of the right ventricular myocardium. We investigated the relationship between the electrocardiogram (ECG) appearances and signal-averaged ECG (SAECG) in 7 cases with ARVD, and evaluated the usefulness of SAECG as a screening test to detect patients with ARVD. Compared with the conventional 12-lead ECG, the SAECG detects abnormalities at a higher rate in ARVD patients (57% versus 86%). SAECG was more sensitive as a screening test to detect patients with ARVD than 12-lead ECG.
authors.affiliation: Department of Laboratory Medicine, Gunma University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sekiguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Miya
authors.forename: Y
authors.initials: Y
authors.lastname: Kaneko
authors.forename: T
authors.initials: T
authors.lastname: Kanda
authors.forename: Y
authors.initials: Y
authors.lastname: Fukumura
authors.forename: N
authors.initials: N
authors.lastname: Kotajima
authors.forename: J
authors.initials: J
authors.lastname: Tamura
authors.forename: I
authors.initials: I
authors.lastname: Kobayashi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy; D004562:Electrocardiography / Q000379:methods; D004699:Endocardium / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology