The retinal input to calbindin-D28k-defined subdivisions in macaque inferior pulvinar.
Several studies have provided evidence for direct retinal input to the pulvinar of macaques monkeys, but there is no general agreement regarding the extent of this projection. Moreover, it is not known how retinal input correlates with chemoarchitectonic subdivisions recently recognized within the large, classical divisions of the pulvinar. The potential implications of this correlation have become more evident after reports that chemoarchitectonic subdivisions of the inferior pulvinar (PI) have specific patterns of connections with cortical visual areas. We have therefore re-examined the retino-PI projection using intraocular injections of horseradish peroxides, and correlated it with pulvinar subdivisions revealed using an antibody for calbindin-D28k. Retinal projections were found preferentially within the medial subdivision of the PI, with some involvement of the posterior and central calbindin-D28k defined subdivisions.
O'Brien
B J
BJ
Neuroanatomie, Max Planck Institut fur Hirnforchung, Deutschordenstrasse 46 D-60528, Frankfurt, Germany.
Abel
P L
PL
Olavarria
J F
JF
D000818:Animals; D064026:Calbindins; D006735:Horseradish Peroxidase; D007150:Immunohistochemistry; D008251:Macaca / Q000033:anatomy & histology* / Q000378:metabolism; D008252:Macaca fascicularis; D008254:Macaca nemestrina; D015335:Molecular Probes; D017729:Presynaptic Terminals / Q000378:metabolism / Q000648:ultrastructure*; D020649:Pulvinar / Q000166:cytology* / Q000378:metabolism; D012160:Retina / Q000166:cytology* / Q000378:metabolism; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*; D014795:Visual Pathways / Q000166:cytology* / Q000378:metabolism; D014796:Visual Perception / Q000502:physiology*
D064026:Calbindins; D015335:Molecular Probes; D064030:S100 Calcium Binding Protein G; D006735:Horseradish Peroxidase