title: [Heroin prescribing: Is there scientific evidence of its efficacy for the treatment of its dependence?].
abstract: It is in the United Kingdom where medical prescription of opiates has been more widely used. Although these practice had been increasing until the sixties, several factors caused a decreased since then, so that it is currently 1.6% of all maintenance programmes, becoming methadone prescription more important. Mainly through studies conducted in Switzerland, the debate over the appropriateness of this practice. In such studies, it appears that heroin prescription supports important improvements in the patients outcome, as it is associated with better retention rates, a reduction in abuse of illicit substances, and improvements in patients health and social aspects. However, methodological limitations of these studies and ambiguous results of studies carried out in other countries, make it difficult to determine the effectiveness or efficacy of this pharmacotherapy, so that more studies are needed to scientifically justify this practice.
authors.affiliation: Servicio de Psiquiatría. Hospital Clínico Universitario de Valencia, Spain. GHAROC@nexo.es
authors.forename: G
authors.initials: G
authors.lastname: Haro
authors.forename: J
authors.initials: J
authors.lastname: Martínez-Raga
authors.forename: M
authors.initials: M
authors.lastname: Castellano
authors.forename: F
authors.initials: F
authors.lastname: Bolinches
authors.forename: P
authors.initials: P
authors.lastname: de Vicente
authors.forename: J C
authors.initials: JC
authors.lastname: Valderrama
mesh_terms: D003932:Heroin / Q000627:therapeutic use*; D006556:Heroin Dependence / Q000188:drug therapy*; D006801:Humans; D009294:Narcotics / Q000627:therapeutic use*; D012106:Research; D013557:Switzerland; D006113:United Kingdom
chemical_list: D009294:Narcotics; D003932:Heroin
vernacular_title: Prescripción médica de heroína: existe evidencia científica de su eficacia en el tratamiento de la dependencia de la misma?