title: [The analysis of the cost structures of the treatment of schizophrenia by means of standardized assessment instruments].
abstract: OBJECTIVE
  Aims of the study are the analysis oft the structures and influence factors causing direct costs of schizophrenic diseases by means of international standardized assessment instruments.
  
  
  METHODS
  Annual costs of treatment were assessed for a sample of 258 patients with the diagnosis of schizophrenia (ICD-10 F20) by means of the German version of the CSSRI. For the analysis of cost variance a regression model was computed using functional level (GAF), symptoms (BPRS 4.0), needs for care (CAN), service satisfaction (VSSS) and subjective quality of life (LQoLP) as predictors.
  
  
  RESULTS
  The average yearly treatment costs for the study sample were 12 726,- DM. Costs for sheltered accommodation and for psychiatric inpatient treatment were found to be the largest elements of the entire costs followed by the costs for ambulant medications. Results of the regression analysis show that illness history, the severity of symptoms and the need for care explain the greatest proportion of variance.
  
  
  CONCLUSIONS
  The standardized instruments developed in the project enable a systematic and international comparable assessment of the costs in the treatment of schizophrenic diseases. Furthermore the instruments allow to explain 38 % of the cost variance. The impact of the severity of symptoms under statistical control of the functional impairment and the needs for care suggests that an effective reduction of symptoms could lead to savings in the entire treatment costs. However, the great influence of the illness history and, irrespective of the functional impairment, the need for care show that the possibilities for cost savings in the treatment of schizophrenia are generally low.
authors.affiliation: Universitätsklinik Leipzig, Klinik und Poliklinik für Psychiatrie. kilr@medizin.uni-leipzig.de
authors.forename: R
authors.initials: R
authors.lastname: Kilian
authors.forename: C
authors.initials: C
authors.lastname: Roick
authors.forename: H
authors.initials: H
authors.lastname: Matschinger
authors.forename: S
authors.initials: S
authors.lastname: Bernert
authors.forename: C
authors.initials: C
authors.lastname: Mory
authors.forename: M C
authors.initials: MC
authors.lastname: Angermeyer
mesh_terms: D000293:Adolescent; D000328:Adult; D000553:Ambulatory Care / Q000191:economics; D017281:Cost of Illness; D003362:Cost-Benefit Analysis; D003365:Costs and Cost Analysis; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D008605:Mental Health Services / Q000191:economics*; D008875:Middle Aged; D009313:National Health Programs / Q000191:economics*; D010343:Patient Admission / Q000191:economics; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000191:economics*
vernacular_title: Die Analyse von Kostenstrukturen im Bereich der Schizophreniebehandlung mit einem standardisierten Instrumentarium.