title: Spontaneous recovery from hypopituitarism in a man with lymphocytic hypophysitis: a case report.
abstract: A 50-year-old man presented with hypopituitarism and a pituitary lesion on magnetic resonance imaging scan. He was diagnosed as having lymphocytic hypophysitis, and replacement therapy with hydrocortisone and thyroxine was started. He regained normal pituitary function after 10 months. Reports of spontaneous recovery from lymphocytic hypophysitis in men are rare. While the natural history of lymphocytic hypophysitis remains elusive and its management is not well established, our report shows that spontaneous resolution may occur with steroid supplementation even in men.
authors.affiliation: Department of Diabetes and Metabolism, Tokyo University Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Noto
authors.forename: K
authors.initials: K
authors.lastname: Tsukamoto
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: K
authors.initials: K
authors.lastname: Takano
authors.forename: T
authors.initials: T
authors.lastname: Fujita
authors.forename: S
authors.initials: S
authors.lastname: Kimura
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D020249:Hormone Replacement Therapy; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000627:therapeutic use; D007018:Hypopituitarism / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D007249:Inflammation / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008214:Lymphocytes; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010900:Pituitary Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D012074:Remission Induction; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D000324:Adrenocorticotropic Hormone; D013974:Thyroxine; D006854:Hydrocortisone