Salvia miltiorrhiza and ischemic diseases.
The demonstration of beneficial effects of salvia miltiorrhiza (DanShen) on ischemic diseases has revolutionized the management of angina pectoris, myocardial infarction (MI) or stroke in Chinese society. Experimental studies have shown that DanShen dilated coronary arteries, increased coronary blood flow, and scavenged free radicals in ischemic diseases, so that it reduced the cellular damage from ischemia and improved heart functions. Clinical trials also indicated that DanShen was an effective medicine for angina pectoris, MI, and stroke. This review will focus on DanShen's effects in angina pectoris, MI and stroke.
Ji
X Y
XY
Department of Pharmacology, Faculty of Medicine, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260.
Tan
B K
BK
Zhu
Y Z
YZ
D000787:Angina Pectoris / Q000188:drug therapy; D000818:Animals; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D016166:Free Radical Scavengers / Q000627:therapeutic use; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy; D017202:Myocardial Ischemia / Q000188:drug therapy*; D010936:Plant Extracts; D010974:Platelet Aggregation / Q000187:drug effects; D027561:Salvia miltiorrhiza; D020521:Stroke / Q000188:drug therapy; D014665:Vasodilator Agents / Q000627:therapeutic use
D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D010936:Plant Extracts; D014665:Vasodilator Agents