[A research on chemical dynamic changes and drug efficacy of shengmaisan compound prescription: chemical researches on shengmaisan prescription(II)].
The content changes of 5-hydroxymethyl-2-furaldehyde(5-HMF), a new compound reported in the previous paper, in eight prescriptions of different composition were further determined by HPLC with a view to find the chemical dynamic changes and compatibility of medicines. The contents of 5-HMF in different combinations of Radix Ophiopogonis and Fructus Schisandrae, different boiling times and boiling frequency were examined. The results indicated that 5-HMF was produced in the boiling process of Radix Ophiopogonis and Fructus Schisandra combined. The contents of 5-HMF would increase with the increase of Radix Ophiopogonis amount, reaching the highest value after 1.5 h boiling and two times of boiling.
Zhu
D
D
Department of Chinese Medicinal Prescription, China Pharmaceutical University, Nanjing 210038.
Li
Z
Z
Yan
Y
Y
Zhu
J
J
D004338:Drug Combinations; D004339:Drug Compounding; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005662:Furaldehyde / Q000031:analogs & derivatives* / Q000032:analysis*; D019668:Liliaceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C008046:5-hydroxymethylfurfural; D005662:Furaldehyde