Rapid disease progression and the rate of spread of the HIV epidemic.
Traditional HIV epidemic models suggest that rapid disease progression may lead to reduced transmission because of a decreased time for the spread of the virus. We present a transmission model structured by age and duration of infection, and propose that rapid disease progression may lead to higher viraemia at a younger age, when individuals are more sexually active. We suggest that rapid disease progression should be considered as a factor in the scale of the HIV epidemic in Africa.
Davenport
M P
MP
School of Pathology, University of New South Wales, Kensington, Australia.
Post
J J
JJ
D000328:Adult; D004196:Disease Outbreaks; D018450:Disease Progression; D015658:HIV Infections / Q000453:epidemiology* / Q000503:physiopathology*; D006801:Humans; D015994:Incidence; D012725:Sexual Behavior