Lack of human papillomavirus types 16 and 18 DNA in esophageal squamous carcinoma cell lines.
OBJECTIVE
To assess the role of human papillomavirus (HPV) in the carcinogenesis of the esophageal carcinomas in a high-incidence geographical area in Northern China.


METHODS
The presence of HPV types 16 and 18 DNA in the three esophageal carcinoma cell lines was examined by type-specific polymerase chain reaction (PCR).


RESULTS
No HPV type 16 and 18 DNA was found in any of the three esophageal carcinoma cell lines.


CONCLUSIONS
The results suggest that the role of HPV in human esophageal carcinogenesis in a high-incidence geographical area remains to be elucidated.
Zheng
J
J
Department of Cell Biology, Cancer Institute, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China. zhengjie@jlonline.com
Fu
M
M
Wang
X
X
Lin
C
C
Wu
M
M
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis*; D004938:Esophageal Neoplasms / Q000473:pathology / Q000821:virology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000145:classification / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000821:virology; D016133:Polymerase Chain Reaction; D014407:Tumor Cells, Cultured; D014412:Tumor Virus Infections / Q000821:virology
D004279:DNA, Viral