title: Late intracaval and intracardiac leiomyomatosis following hysterectomy for benign myomas treated by surgery and GnRH agonist.
abstract: BACKGROUND
  The aim of this study was to report an exceptional case of a patient presenting with intracaval and intracardiac leiomyomatosis treated by combined surgical and medical treatment.
  
  
  METHODS
  A 48-year-old presented with intracaval and intracardiac leiomyomatosis (IL) discovered 6 years following a total hysterectomy with ovarian conservation for myomas. Surgical resection of the pelvic myomas and intracaval leiomyomatosis was performed during the same surgical procedure. Given the presence of a small tumor residuum in the pelvic cavity, postoperative medical treatment based on a gonadotropin-releasing hormone (GnRH) agonist was delivered for 1 year. The patient was followed-up using clinical examination and systematic CT scan. Ten months following the end of medical treatment, she is still in good health and the pelvic residuum has stabilized.
  
  
  CONCLUSIONS
  Patients with pelvic tumor combined with IL could be treated using a one-stage surgical procedure. In cases of incomplete surgical resection, medical treatment based on GnRH agonist could be successfully delivered.
authors.affiliation: Department of Gynecologic Surgery, Institut Gustave Roussy, Villejuif Cédex, 94805, France. morice@igr.fr
authors.forename: P
authors.initials: P
authors.lastname: Morice
authors.forename: A
authors.initials: A
authors.lastname: Chapelier
authors.forename: P
authors.initials: P
authors.lastname: Dartevelle
authors.forename: D
authors.initials: D
authors.lastname: Castaigne
authors.forename: C
authors.initials: C
authors.lastname: Lhommé
mesh_terms: D018229:Angiomyoma / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D005260:Female; D006338:Heart Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007044:Hysterectomy; D018231:Leiomyomatosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D016729:Leuprolide / Q000627:therapeutic use*; D008875:Middle Aged; D010386:Pelvic Neoplasms / Q000188:drug therapy / Q000601:surgery; D019043:Vascular Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D016729:Leuprolide