title: A mimicking enzyme analogue for chemical sensors.
abstract: An artificial enzyme analogue of Nafion/lead-ruthenium oxide pyrochlore (Py) chemically modified electrode (NPyCME) is synthesized by in situ precipitation through blocking of Nafion's hydrophilic zones. The catalytically active Py sites covered with a hydrophobic core of Nafion resemble an enzymatic structure. Moreover, the NPyCME obeys the Michaelis-Menten mechanism for the oxidation of many organic and biological molecules. This Account highlights aspects of the preparation, characterization, and application of the NPyCME.
authors.affiliation: Department of Chemistry, National Chung-Hsing University, Taichung 402, Taiwan. jmzen@dragon.nchu.edu.tw
authors.forename: J M
authors.initials: JM
authors.lastname: Zen
authors.forename: A S
authors.initials: AS
authors.lastname: Kumar
mesh_terms: D015374:Biosensing Techniques; D002384:Catalysis; D005465:Fluorocarbon Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D007854:Lead / Q000737:chemistry; D009556:Niobium / Q000737:chemistry; D010087:Oxides / Q000138:chemical synthesis / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry
chemical_list: D005465:Fluorocarbon Polymers; D010087:Oxides; D009556:Niobium; D007854:Lead; C040402:perfluorosulfonic acid; D012428:Ruthenium