[Multidrug-resistant and fluoroquinolone-resistant Salmonella enterica serotype Typhimurium definitive phage type 12 isolated from infantile diarrhea].
A 35-day-old male infant was admitted to our hospital, presenting a high fever, vomiting, and diarrhea. Multidrug-resistant and fluoroquinolon-resistant Salmonella serotype Typhimurium was isolated from his stool. The phage type of the strain was DT12. The strain was resistant to ampicillin, streptomycin, gentamicin, tetracycline, chloramphenicol, sulfamethoxazole-trimethoprim, and fluoroquinolones (levofloxacin; MIC 8 micrograms/ml, norfloxacin; 24 micrograms/ml, ciprofloxacin; 16 micrograms/ml, sparfloxacin; 32 micrograms/ml). He was cured by antibiotic therapy using fosfomycin (< or = 1 microgram/ml). We could not determine a route of infection. Domestic surveillance for fluoroquinolon-resistant Sallmonella is necessary.
Nakaya
H
H
Department of Clinical Center Laboratory, Kansai Medical University.
Yasuhara
A
A
Yoshimura
K
K
Oshihoi
Y
Y
Izumiya
H
H
Watanabe
H
H
D000890:Anti-Infective Agents / Q000494:pharmacology*; D003968:Diarrhea, Infantile / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D024841:Fluoroquinolones; D006801:Humans; D007223:Infant; D008297:Male; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000302:isolation & purification*
D000890:Anti-Infective Agents; D024841:Fluoroquinolones