title: [Leishmania (Leishmania) chagasi infection in children from an endemic area of visceral leishmaniasis in the São Luís Island-MA, Brazil].
abstract: A prospective study was undertaken in 648 children with less than 6 years of age in the municipality of Raposa, Maranhão, Brazil, from June 1997 to June 1998, to evaluate the characteristics of the infection by L.(L.)chagasi and verify if there is an association between malnutrition and asymptomatic infection. A standardized questionnaire was used containing socioeconomic, environmental and behavioral data. Montenegro skin reaction (IDRM) with L. amazonensis and Enzyme Linked Immunosorbent Assay (ELISA) test to detect infection, and anthropometric examination were performed. Initial and final prevalence and incidence of infection were 18.6%, 20.6% and 10.8% as measured by IDRM and 13.5%, 34.4% and 28% according to ELISA. The prevalence of chronic malnutrition was 26%. No association was detected between malnutrition and asymptomatic infection by L. (L.) chagasi. More effective control measures are needed in these areas since asymptomatic infection seems to be on the increase.
authors.affiliation: Departamento de Enfermagem, Universidade Federal do Maranhão, São Luís, MA, Brasil. ajmc@elo.com.br
authors.forename: A J
authors.initials: AJ
authors.lastname: Caldas
authors.forename: D R
authors.initials: DR
authors.lastname: Silva
authors.forename: C C
authors.initials: CC
authors.lastname: Pereira
authors.forename: P M
authors.initials: PM
authors.lastname: Nunes
authors.forename: B P
authors.initials: BP
authors.lastname: Silva
authors.forename: A A
authors.initials: AA
authors.lastname: Silva
authors.forename: A
authors.initials: A
authors.lastname: Barral
authors.forename: J M
authors.initials: JM
authors.lastname: Costa
mesh_terms: D001938:Brazil; D002675:Child, Preschool; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D007223:Infant; D007898:Leishmaniasis, Visceral / Q000453:epidemiology*; D008297:Male; D011446:Prospective Studies
vernacular_title: Infecção por Leishmania (Leishmania) chagasi em crianças de uma área endêmica de leishmaniose visceral americana na Ilha de São Luis-MA, Brasil.