title: [Effect of low-intensity electromagnetic fields of industrial frequency on the ultrastructure and proliferative activity of rat's thymus cells].
abstract: Effects of two types of low-intensity electromagnetic fields (EMF) of industrial frequency (50 Hz) on the fine structure and proliferative activity of thymic cells in white rats were studied. It was found that a weak EMF with a prevailing electrical component (380-480 V/m, 120-140 nT1) did not affect the DNA synthesis intensity. An EMF with a stronger magnetic induction (10-15 V/m, 800-1500 nT1) diminished the glucose-6-phosphate dehydrogenase activity and proliferative processes in cultured stimulated lymphocytes. Electron microscopic investigation of the thymus after both types of exposure revealed an accumulation of lymphocytes with pyknotic nuclei and electron-dense cytoplasm, as well as hypoplasia of the vascular endothelium. At the same time, EMF with a prevailing magnetic component produced a more marked negative effect on the ultrastructure of thymic cells, which indicated a lowered secretory activity of epitheliocytes.
authors.affiliation: Institute of Physiology, National Academy of Sciences, Minsk, 220072 Belarus. biblio@fizio.bas-net.by
authors.forename: T I
authors.initials: TI
authors.lastname: Zhitkevich
authors.forename: T B
authors.initials: TB
authors.lastname: Bokut'
authors.forename: N I
authors.initials: NI
authors.lastname: Netukova
mesh_terms: D000818:Animals; D002455:Cell Division / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004574:Electromagnetic Fields; D008297:Male; D016273:Occupational Exposure; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000528:radiation effects* / Q000648:ultrastructure*
vernacular_title: Vliianie nizkointensivnykh élektromagnitnykh poleĭ promyshlennoĭ chastoty na ul'trastrukturu i proliferativnuiu aktivnost' kletok timusa krys.