[Effect of rotundine on gastric acid and pepsin activity in rats].
A test was made on the effect of rotundine on the secretion of gastric acid and pepsin activity in rats. Compared with the control group, rotundine(> or = 17.1 mg/kg) inhibited gastric acid and decreased secretion of gastric juice(P < 0.01), but had no influence on pepsin activity. There was a negative relationship between total acidity and pH of gastric juice (r = -0.9818).
Zhou
M
M
Department of Clinical Pharmacy, Wuhan Central Railway Hospital, Wuhan 430064.
Li
X
X
Geng
L
L
Qu
C
C
Peng
S
S
D000818:Animals; D001600:Berberine Alkaloids / Q000494:pharmacology*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005750:Gastric Juice / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D008297:Male; D010434:Pepsin A / Q000378:metabolism*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
D001600:Berberine Alkaloids; C014215:tetrahydropalmatine; D010434:Pepsin A