Anti-inflammatory drugs. X. Hydrated pyrrolidinium [2-[(2,6-dichlorophenyl)amino]phenyl]acetate(HP.D.H2O).
In the solid-state structure of the title compound, C(4)H(10)N(+).C(14)H(10)Cl(2)NO(2)(-).H(2)O, the asymmetric unit contains one cation, one anion and a water molecule. There is a network of hydrogen bonds which is similar to that found in the hydrated diethylammonium diclofenac salt. A comparison is made of the molecular conformation of the anions in the two related structures.
Castellari
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C
Dipartimento di Chimica G. Ciamician, Universitá di Bologna, Via Selmi 2, 40126 Bologna, Italy.
Comelli
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F
Ottani
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D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004008:Diclofenac / Q000737:chemistry; D006860:Hydrogen Bonding; D008958:Models, Molecular; D011759:Pyrrolidines / Q000737:chemistry / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011759:Pyrrolidines; C441504:hydrated pyrrolidinium (2-((2,6-dichlorophenyl)amino)phenyl)acetate; D004008:Diclofenac