[The effect of Codonopsis pilosula (Franch.) Nannf. on gastric acid, serum gastrin and plasma somatostatin concentration in dogs].
The results were obtained by oral administration of the decoction of Codonopsis pilosula in three different doses(10 g, 20 g, 40 g) to 5 dogs with Heidenhain pouch. No significant changes occurred in the acidity output of Heidenhain pouch and plasma somatostatin concentration out of the oral administration (P > 0.05). A significant increase occurred in serum gastrin concentration (P < 0.05 or P < 0.01) 150 min after a dose of 10 g, 90 min and 150 min after doses of 20 g, and 30 min, 60 min, and 150 min after doses of 40 g.
Chen
S
S
Second Clinical College of China Medical University, Shenyang 110003.
Zhou
Z
Z
Sun
S
S
Li
Y
Y
Li
X
X
D000818:Animals; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism; D005755:Gastrins / Q000097:blood*; D019684:Magnoliopsida / Q000737:chemistry; D008297:Male; D010946:Plants, Medicinal; D013004:Somatostatin / Q000097:blood*
D004365:Drugs, Chinese Herbal; D005755:Gastrins; D013004:Somatostatin