Construction of a bispecific single chain antibody for recruitment of cytotoxic T cells to the tumour stroma associated antigen fibroblast activation protein.
D000818:Animals; D018033:Antibodies, Bispecific / Q000096:biosynthesis* / Q000235:genetics / Q000627:therapeutic use; D000951:Antigens, Neoplasm; D001483:Base Sequence; D014408:Biomarkers, Tumor; D001709:Biotechnology; D017252:CD3 Complex; D016466:CHO Cells; D002460:Cell Line; D003001:Cloning, Molecular; D006224:Cricetinae; D004274:DNA, Recombinant / Q000235:genetics; D010450:Endopeptidases; D018093:Gelatinases; D005822:Genetic Vectors; D006133:Growth Substances / Q000276:immunology*; D006801:Humans; D007167:Immunotherapy; D066298:In Vitro Techniques; D008213:Lymphocyte Activation; D008565:Membrane Proteins; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy*; D012697:Serine Endopeptidases / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D014407:Tumor Cells, Cultured; D000099167:Fibroblast Activation Protein Alpha