Additive activation of hepatic NF-kappaB by ethanol and hepatitis B protein X (HBX) or HCV core protein: involvement of TNF-alpha receptor 1-independent and -dependent mechanisms.
D000079:Acetaldehyde / Q000494:pharmacology; D000818:Animals; D015703:Antigens, CD / Q000235:genetics / Q000502:physiology; D002478:Cells, Cultured; D000431:Ethanol / Q000494:pharmacology*; D019204:GTP-Binding Proteins / Q000378:metabolism; D005822:Genetic Vectors / Q000235:genetics; D005838:Genotype; D006515:Hepatitis B virus / Q000235:genetics; D022781:Hepatocytes / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D051550:I-kappa B Kinase; D020672:I-kappa B Proteins / Q000235:genetics / Q000502:physiology; D008099:Liver / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D016328:NF-kappa B / Q000187:drug effects* / Q000378:metabolism; D037342:Pertussis Toxin; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000502:physiology; D018124:Receptors, Tumor Necrosis Factor / Q000235:genetics / Q000502:physiology; D047888:Receptors, Tumor Necrosis Factor, Type I; D047889:Receptors, Tumor Necrosis Factor, Type II; D015398:Signal Transduction / Q000187:drug effects; D015534:Trans-Activators; D014162:Transfection; D014407:Tumor Cells, Cultured; D014758:Viral Core Proteins / Q000235:genetics / Q000502:physiology*; D054334:Viral Regulatory and Accessory Proteins / Q000235:genetics / Q000502:physiology*; D010566:Virulence Factors, Bordetella / Q000494:pharmacology; D000097782:NF-kappaB-Inducing Kinase