Defects of the insulin receptor substrate (IRS) system in human metabolic disorders.
D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology* / Q000235:genetics; D006801:Humans; D007328:Insulin / Q000502:physiology; D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008659:Metabolic Diseases / Q000209:etiology; D051379:Mice; D018345:Mice, Knockout; D008954:Models, Biological; D010750:Phosphoproteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D011110:Polymorphism, Genetic; D017434:Protein Structure, Tertiary