Modeling Huntington's disease in cells, flies, and mice.
D000818:Animals; D030801:Animals, Genetically Modified; D017209:Apoptosis / Q000502:physiology; D017173:Caenorhabditis elegans; D002461:Cell Line, Transformed / Q000378:metabolism; D002478:Cells, Cultured / Q000378:metabolism / Q000473:pathology; D003342:Corpus Striatum / Q000378:metabolism / Q000473:pathology; D003546:Cysteine Endopeptidases / Q000502:physiology; D004195:Disease Models, Animal; D004331:Drosophila melanogaster; D005314:Embryonic and Fetal Development / Q000235:genetics; D005326:Fetal Proteins / Q000502:physiology; D005799:Genes, Dominant; D005804:Genes, Lethal; D000882:Haplorhini; D006801:Humans; D000071058:Huntingtin Protein; D006816:Huntington Disease / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D007668:Kidney; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D016202:N-Methylaspartate / Q000494:pharmacology; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000172:deficiency / Q000235:genetics / Q000502:physiology; D009474:Neurons / Q000378:metabolism / Q000473:pathology; D009687:Nuclear Proteins / Q000737:chemistry / Q000172:deficiency / Q000235:genetics / Q000502:physiology; D016716:PC12 Cells / Q000378:metabolism; D010446:Peptide Fragments / Q000235:genetics; D025941:Protein Interaction Mapping; D051381:Rats; D018911:Trinucleotide Repeats