Effect of YM-40461, a novel surfactant secretagogue, on chronic obstructive pulmonary diseases and similar symptoms in guinea pigs.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001784:Blood Gas Analysis; D016535:Bronchial Hyperreactivity / Q000139:chemically induced / Q000517:prevention & control; D001991:Bronchitis / Q000139:chemically induced / Q000517:prevention & control; D006168:Guinea Pigs; D000860:Hypoxia / Q000139:chemically induced / Q000517:prevention & control; D008297:Male; D010671:Phenylurea Compounds / Q000627:therapeutic use*; D029424:Pulmonary Disease, Chronic Obstructive / Q000139:chemically induced / Q000188:drug therapy*; D012129:Respiratory Function Tests; D013458:Sulfur Dioxide; D013501:Surface-Active Agents / Q000627:therapeutic use*