Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000201:enzymology* / Q000473:pathology; D002540:Cerebral Cortex / Q000201:enzymology / Q000473:pathology; D004789:Enzyme Activation; D006624:Hippocampus / Q000201:enzymology / Q000473:pathology; D006801:Humans; D048031:JNK Mitogen-Activated Protein Kinases; D008875:Middle Aged; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism*; D048052:Mitogen-Activated Protein Kinase 3; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D009474:Neurons / Q000201:enzymology*; D010766:Phosphorylation; D048051:p38 Mitogen-Activated Protein Kinases