The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases.
D008841:Actin Cytoskeleton / Q000648:ultrastructure*; D000818:Animals; D019556:COS Cells; D003593:Cytoplasm / Q000378:metabolism; D003599:Cytoskeleton / Q000648:ultrastructure; D004789:Enzyme Activation; D016350:Leucine Zippers; D008840:Microfilament Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D008856:Microscopy, Fluorescence; D008954:Models, Biological; D009154:Mutation; D010750:Phosphoproteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D010766:Phosphorylation; D019000:Phosphotyrosine / Q000378:metabolism; D014162:Transfection; D020742:rhoA GTP-Binding Protein / Q000502:physiology; D018909:src Homology Domains; D019061:src-Family Kinases / Q000378:metabolism*