Multiple mutations at the active site of naphthalene dioxygenase affect regioselectivity and enantioselectivity.
D001665:Binding Sites; D001713:Biphenyl Compounds / Q000378:metabolism; D015153:Blotting, Western; D049308:Dioxygenases; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D006841:Hydrocarbons, Aromatic / Q000378:metabolism*; D007211:Indoles / Q000378:metabolism; D009097:Multienzyme Complexes / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D016297:Mutagenesis, Site-Directed; D009281:Naphthalenes / Q000378:metabolism; D010105:Oxygenases / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D010616:Phenanthrenes / Q000378:metabolism; D011487:Protein Conformation; D011549:Pseudomonas / Q000201:enzymology; D013237:Stereoisomerism; D013379:Substrate Specificity; D014050:Toluene / Q000031:analogs & derivatives* / Q000378:metabolism