The role of ceramide in receptor- and stress-induced apoptosis studied in acidic ceramidase-deficient Farber disease cells.
D000970:Antineoplastic Agents / Q000494:pharmacology; D017209:Apoptosis; D020169:Caspases / Q000378:metabolism; D002478:Cells, Cultured; D002518:Ceramides / Q000494:pharmacology / Q000502:physiology*; D002675:Child, Preschool; D004249:DNA Damage; D003630:Daunorubicin / Q000494:pharmacology; D004317:Doxorubicin / Q000494:pharmacology; D005260:Female; D005347:Fibroblasts / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D002517:Galactosylgalactosylglucosylceramidase / Q000172:deficiency*; D005720:Gamma Rays / Q000009:adverse effects; D006801:Humans; D007700:Kinetics; D008214:Lymphocytes / Q000187:drug effects / Q000473:pathology; D016464:Lysosomal Storage Diseases / Q000201:enzymology / Q000473:pathology*; D019311:Staurosporine / Q000494:pharmacology; D019014:fas Receptor / Q000502:physiology*