Identification of essential residues involved in the glutamate binding pocket of the group II metabotropic glutamate receptor.
D000596:Amino Acids / Q000378:metabolism; D001643:Bridged Bicyclo Compounds / Q000494:pharmacology; D002478:Cells, Cultured; D004594:Electrophysiology; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels; D018698:Glutamic Acid / Q000378:metabolism*; D016244:Guanosine 5'-O-(3-Thiotriphosphate) / Q000378:metabolism; D006801:Humans; D008958:Models, Molecular; D017354:Point Mutation; D015221:Potassium Channels / Q000235:genetics / Q000502:physiology; D024661:Potassium Channels, Inwardly Rectifying; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D018094:Receptors, Metabotropic Glutamate / Q000819:agonists / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*; D013462:Sulfur Radioisotopes