Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signaling.
D000818:Animals; D002454:Cell Differentiation; D002470:Cell Survival; D002478:Cells, Cultured; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology*; D006609:High Mobility Group Proteins / Q000235:genetics / Q000502:physiology*; D006627:Hirschsprung Disease / Q000235:genetics; D006801:Humans; D017403:In Situ Hybridization; D051379:Mice; D009154:Mutation; D009432:Neural Crest / Q000166:cytology* / Q000502:physiology; D020890:Neuregulin-1 / Q000235:genetics / Q000502:physiology; D009457:Neuroglia / Q000166:cytology* / Q000502:physiology; D010641:Phenotype; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D055757:SOXE Transcription Factors; D015398:Signal Transduction; D013234:Stem Cells / Q000166:cytology / Q000502:physiology; D014157:Transcription Factors; D014849:Waardenburg Syndrome / Q000235:genetics