Blockade of endothelin receptors reduces diet-induced hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice.
D000818:Animals; D001011:Aorta / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D001057:Apolipoproteins E / Q000172:deficiency*; D001161:Arteriosclerosis / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D001794:Blood Pressure / Q000187:drug effects; D002791:Cholesterol, Dietary; D015243:Cholesterol, VLDL / Q000097:blood; D004032:Diet; D004195:Disease Models, Animal; D065128:Endothelin Receptor Antagonists; D019332:Endothelin-1 / Q000032:analysis / Q000097:blood; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D007189:Indans / Q000494:pharmacology / Q000627:therapeutic use*; D008074:Lipoproteins / Q000097:blood; D008297:Male; D051379:Mice; D014280:Triglycerides / Q000097:blood