alpha-Naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6.
D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases; D001571:Benzoflavones / Q000378:metabolism / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D065607:Cytochrome P-450 Enzyme Inhibitors; D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004917:Erythromycin / Q000378:metabolism; D004958:Estradiol / Q000378:metabolism; D006900:Hydroxylation; D008297:Male; D008745:Methylation; D008862:Microsomes, Liver / Q000187:drug effects* / Q000201:enzymology; D011817:Rabbits; D011994:Recombinant Proteins; D013629:Tamoxifen / Q000378:metabolism