Vestibular histofluorescence could be due to accumulation of both the antibiotic and its derivative, streptidine, after acute streptomycin treatment in the guinea pig.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D001711:Biotransformation; D002021:Buffers; D005453:Fluorescence; D005557:Formaldehyde; D006146:Guanidines / Q000378:metabolism*; D006168:Guinea Pigs; D006595:Hexosamines / Q000378:metabolism*; D008297:Male; D018613:Microscopy, Confocal; D012996:Solutions; D013050:Spectrometry, Fluorescence; D013307:Streptomycin / Q000378:metabolism*; D016610:Tissue Embedding; D016707:Tissue Fixation; D014722:Vestibule, Labyrinth / Q000378:metabolism*