Protecting the "animal of necessity": limits to inquiry in clinical investigation.
D035843:Biomedical Research; D032781:Codes of Ethics; D017041:Ethics Committees; D028744:Ethics Committees, Research; D004992:Ethics, Medical / Q000266:history*; D004995:Ethics, Professional; D035082:Federal Government; D006076:Government; D033161:Government Regulation; D049711:History, Modern 1601-; D006805:Human Experimentation; D006801:Humans; D007258:Informed Consent; D007603:Jurisprudence; D004364:Pharmaceutical Preparations; D011057:Politics; D011640:Public Policy; D012106:Research / Q000266:history*; D012108:Research Personnel; D012926:Social Control, Formal; D012927:Social Control, Informal; D014481:United States