Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells.
D000818:Animals; D019393:Arrestin / Q000378:metabolism*; D019390:Arrestins / Q000494:pharmacology; D002478:Cells, Cultured; D017868:Cyclic AMP-Dependent Protein Kinases / Q000378:metabolism*; D034281:Dynamins; D004705:Endocytosis / Q000187:drug effects; D054774:G-Protein-Coupled Receptor Kinase 5; D020558:GTP Phosphohydrolases / Q000494:pharmacology*; D005910:Glioma / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000166:cytology / Q000196:embryology; D010750:Phosphoproteins / Q000494:pharmacology; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D051381:Rats; D044402:Receptor, Serotonin, 5-HT2A; D018343:Receptors, Adrenergic, beta-2 / Q000187:drug effects / Q000378:metabolism; D011985:Receptors, Serotonin / Q000187:drug effects / Q000378:metabolism*; D014407:Tumor Cells, Cultured; D051552:beta-Adrenergic Receptor Kinases