Gitelman's syndrome first diagnosed as Bartter's syndrome.
A 29-year-old man, who had been treated with potassium, spironolactone and indomethacin for over 9 years, was admitted because of nausea, vomiting, diarrhea and tetany manifestation. At the age of 20, he had been diagnosed as having Bartter's syndrome according to the criteria of the Japanese Ministry of Health and Welfare. Findings on admission were hypokalemia, hypomagnesemia and hypocalciuria. Renal distal fractional reabsorption rates of sodium, chloride and calcium were markedly decreased by administration of furosemide but there was no obvious change with administration of thiazide. These findings indicate that the patient had Gitelman's syndrome rather than Bartter's syndrome.
Tsuchiya
H
H
Diabetes Center and the Department of Medicine, Nagaoka Red Cross Hospital.
Kamoi
K
K
Soda
S
S
Sasaki
H
H
Kobayashi
K
K
Hayashi
M
M
D000328:Adult; D001477:Bartter Syndrome / Q000175:diagnosis*; D001581:Benzothiadiazines; D002118:Calcium / Q000652:urine*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004232:Diuretics; D005665:Furosemide; D006801:Humans; D008274:Magnesium / Q000097:blood*; D008297:Male; D011188:Potassium / Q000097:blood*; D012008:Recurrence; D049993:Sodium Chloride Symporter Inhibitors; D013577:Syndrome
D001581:Benzothiadiazines; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D005665:Furosemide; D008274:Magnesium; D011188:Potassium; D002118:Calcium