title: Ménière's disease and delayed endolymphatic hydrops in children.
abstract: In order to study the characteristics of pediatric patients (< or = 15 years at onset) with endolymphatic hydrops disorders, we selected 5 patients with Ménière's disease (MD) and 3 patients with delayed endolymphatic hydrops (DEH) from 7418 patients who had visited the Neurotological Clinic of the Toyama Medical and Pharmaceutical University Hospital between 1979 and 1999. Clinical features were characterized as follows: (i) pediatric MD patients were rare, comprising approximately 1.5% of all the 337 MD patients in the sample; (ii) a fluctuating hearing loss, strong positive response in glycerol test, high SP/AP amplitude ratio in electrocochleography and moderate positive response in furosemide vestibulo-ocular reflex test were recorded; (iii) in 2 of the 5 pediatric MD patients, vertiginous attacks had persisted for a long period and they had undergone surgical procedures (sac operation and vestibular neurectomy); and (iv) the ipsilateral type of DEH was observed in 2/3 children, and contralateral DEH in 1/3.
authors.affiliation: Health Services Facility for the Aged Amenity Nobukiyo, Toyama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Mizukoshi
authors.forename: H
authors.initials: H
authors.lastname: Shojaku
authors.forename: S
authors.initials: S
authors.lastname: Aso
authors.forename: M
authors.initials: M
authors.lastname: Asai
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
mesh_terms: D000293:Adolescent; D001300:Audiometry, Evoked Response; D002648:Child; D004232:Diuretics / Q000627:therapeutic use; D004322:Drainage; D018159:Endolymphatic Hydrops / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005665:Furosemide / Q000627:therapeutic use; D006311:Hearing Disorders / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology; D012189:Retrospective Studies
chemical_list: D004232:Diuretics; D005665:Furosemide