Long-term immunosuppression and drug interactions.
1. Early patient and graft survival are excellent after liver transplantation. 2. The focus must be on reducing toxicity associated with long-term immunosuppression. 3. Available new drugs offer the potential to reduce toxicity by combination therapy or replacement of toxic agents. 4. Individual patient immunosuppressive protocols should be developed. 5. Drug interactions are common and the source of significant morbidity.
Levy
G A
GA
Multi Organ Transplant Program, Toronto General Hospital, University of Toronto, Ontario, Canada. glfgl2@attglobal.net
D004347:Drug Interactions; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use; D016031:Liver Transplantation; D013997:Time Factors
D007166:Immunosuppressive Agents