title: Room-Temperature Palladium-Catalyzed Amination of Aryl Bromides and Chlorides and Extended Scope of Aromatic C-N Bond Formation with a Commercial Ligand.
abstract: The reactions of aryl bromides with amines occurs at room temperature when using Pd(0) and P(t-Bu)(3) in a 1:1 ratio, and the reactions of aryl chlorides occur at room temperature or 70 degrees C. The arylation of indoles and the new arylation of carbamates also occur when using P(t-Bu)(3) as ligand.
authors.affiliation: Department of Chemistry, Yale University P.O. Box 208107, New Haven, Connecticut 06520-8107.
authors.forename: John F.
authors.initials: JF
authors.lastname: Hartwig
authors.forename: Motoi
authors.initials: M
authors.lastname: Kawatsura
authors.forename: Sheila I.
authors.initials: SI
authors.lastname: Hauck
authors.forename: Kevin H.
authors.initials: KH
authors.lastname: Shaughnessy
authors.forename: Luis M.
authors.initials: LM
authors.lastname: Alcazar-Roman