Adociasulfates 1, 7, and 8: New Bioactive Hexaprenoid Hydroquinones from the Marine Sponge Adocia sp.
Adociasulfate 1 (1), adociasulfate 7 (2), and adociasulfate 8 (3), which are inhibitors of proton pump activity in hen bone-derived membrane vesicles, were isolated from an extract of the sponge Adocia sp. (Chalinidae). Structure elucidation by 2D-NMR spectroscopy revealed that they are novel hexaprenoid hydroquinone sulfates.
Kalaitzis
John A.
JA
Queensland Pharmaceutical Research Institute, Griffith University, Brisbane 4111, Australia, and Queensland Museum, South Brisbane, Queensland 4101, Australia.
de Almeida Leone
Priscila
P
Harris
Lisa
L
Butler
Mark S.
MS
Ngo
Anna
A
Hooper
John N. A.
JN
Quinn
Ronald J.
RJ