title: Ring-Opening Cycloaddition of Aziridines to Ketenimines.
abstract: The Lewis acid-catalyzed addition of aziridines to ketenimines gave substituted pyrrolidonimines in 47-87% yields. The hard Lewis acid LiClO(4) proved to be superior to the soft [(PhCN)(2)PdCl(2)], affording higher yields under milder conditions. The reaction is regioselective and occurs with complete stereoselectivity using [(PhCN)(2)PdCl(2)] and with a small amount of racemization in the case of LiClO(4).
authors.affiliation: Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, Ontario, Canada K1N 6N5.
authors.forename: Heiko
authors.initials: H
authors.lastname: Maas
authors.forename: Corinne
authors.initials: C
authors.lastname: Bensimon
authors.forename: Howard
authors.initials: H
authors.lastname: Alper