title: Renal vascular resistance in progressive systemic sclerosis: evaluation with duplex Doppler ultrasound.
abstract: The study was planned to evaluate renal vascular resistance by means of duplex Doppler ultrasonography in patients with progressive systemic sclerosis (PSS) with or without signs of renal involvement. Twenty-two female patients with PSS (mean age 38.5 +/- 17.3 years) and 20 age-matched (mean age 36.7 +/- 7.2 years) female healthy controls participated to the study. Doppler indices of renal vascular resistance--resistive index (RI), pulsative index (PI), and systolic-to-diastolic flow velocities ratio (S/D ratio)--were determined on main renal artery and interlobar artery. RI, PI and S/D ratio were found to be increased in PSS patients with signs of renal involvement as compared to those without renal manifestations and healthy controls (p<0.0001 for all groups). Doppler indices of renal vascular resistance were closely related to the duration of the disease, age, and plasma renin activity. Doppler ultrasound is a useful and informative technique in the monitoring of PSS patients with renal involvement.
authors.affiliation: Department of Radiology, Cukurova University, Medical Faculty, Adana, Turkey. kairgeldy@usa.net
authors.forename: K S
authors.initials: KS
authors.lastname: Aikimbaev
authors.forename: A
authors.initials: A
authors.lastname: Canataroğlu
authors.forename: S
authors.initials: S
authors.lastname: Ozbek
authors.forename: A
authors.initials: A
authors.lastname: Usal
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001783:Blood Flow Velocity / Q000502:physiology; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology; D008875:Middle Aged; D011673:Pulsatile Flow / Q000502:physiology; D012044:Regression Analysis; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D012079:Renal Circulation / Q000502:physiology*; D012083:Renin / Q000097:blood; D012595:Scleroderma, Systemic / Q000097:blood / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D018616:Ultrasonography, Doppler, Duplex; D014655:Vascular Resistance / Q000502:physiology*
chemical_list: D003404:Creatinine; D012083:Renin