title: Type B1 thymoma in multiple endocrine neoplasia type 1 (MEN-1) syndrome.
abstract: OBJECTIVE
  Multiple endocrine neoplasia (MEN) syndromes include a group of disorders characterized by the neoplastic transformation of two or more endocrine tissues. In type 1 syndrome (MEN-1), pituitary, parathyroid and pancreatic islet tumors are most frequently represented. Thymic neoplasms are also rarely associated, and thymectomy during subtotal or total parathyroidectomy should always be considered.
  
  
  METHODS
  The authors describe a rare case of a 22-year-old male who presented a type B1 thymoma without myasthenia gravis associated to hyperparathyroidism, corticoadrenal adenoma and three neuroendocrine pancreatic lesions (somatostatinoma, glucagonoma and insulinoma).
authors.affiliation: Department of Surgery Pietro Valdoni, University of Rome La Sapienza, Italy. detoma@uniroma1.it
authors.forename: G
authors.initials: G
authors.lastname: De Toma
authors.forename: M
authors.initials: M
authors.lastname: Plocco
authors.forename: V
authors.initials: V
authors.lastname: Nicolanti
authors.forename: S
authors.initials: S
authors.lastname: Brozzetti
authors.forename: C
authors.initials: C
authors.lastname: Letizia
authors.forename: A
authors.initials: A
authors.lastname: Cavallaro
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D018761:Multiple Endocrine Neoplasia Type 1 / Q000473:pathology*; D011859:Radiography; D013945:Thymoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology