Synthesis and Reactions of 3-(Nosyloxy)-2-keto Esters.
A series of 3-(nosyloxy)-2-keto esters 7a-j were prepared from the corresponding alpha-keto esters by conversion to the trimethylsilyl enol ether and reaction with p-nitrobenzenesulfonyl peroxide. Conversion of these materials to 1,2,3-trifunctionalized compounds is described, and comparison of their properties with isomeric 2-(nosyloxy)-3-keto esters is discussed.
Hoffman
Robert V.
RV
Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003-0001.
Johnson
M. Catherine
MC
Okonya
John F.
JF