EEG mapping and functional MRI in presurgical epilepsy evaluation.
The major goal of presurgical epilepsy evaluation is the correct and precise identification of the epileptic focus. Functional magnetic resonance imaging (fMRI) and EEG source analysis (EEG mapping) are two recent developments that are increasingly used in this particular clinical context. fMRI yields anatomically precise information but low temporal resolution, whereas the inverse situation is true for EEG mapping. Important complementary information is therefore obtained by integrating the results from each technique. Recent advances in these two fields are discussed, with particular reference to epileptic focus localization. Such a combined approach is shown to be a powerful tool, in particular in patients with non-lesional and/or extratemporal epilepsy still considered to be difficult surgical candidates.
Seeck
M
M
Laboratory of Presurgical Epilepsy Evaluation "Functional Neurology and Neurosurgery". Program of the University Hospitals Lausanne and Geneva, Switzerland. margitta.seeck@hcuge.ch
Michel
C M
CM
Spinelli
L
L
Lazeyras
F
F
D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology / Q000601:surgery; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging