title: Bengazoles C-G from the Sponge Jaspis sp. Synthesis of the Side Chain and Determination of Absolute Configuration.
abstract: Five new antifungal bengazoles (C-G) were isolated and fully characterized from a marine sponge of the genus Jaspis sp. Bengazoles C-G, together with the known bengazoles A and B, comprise a homologous series of n, iso, and anteiso fatty acid esters (C(13)-C(16)) of the same heterocyclic bis(oxazolyl)methanol parent. The complete relative and absolute configurations of the bengazoles were determined by application of the modified Mosher method and interpretation of exciton coupling in the CD spectra of the tetra-p-bromobenzoate derivatives of bengazole A and that of a model tetrol synthesized in seven steps from L-fucose.
authors.affiliation: Department of Chemistry, University of California, Davis, California 95616.
authors.forename: Philip A.
authors.initials: PA
authors.lastname: Searle
authors.forename: Rowena K.
authors.initials: RK
authors.lastname: Richter
authors.forename: Tadeusz F.
authors.initials: TF
authors.lastname: Molinski