Interleukin-4 production in BALB/c mice immunized with Anisakis simplex.
We investigated the interleukin (IL-4) levels in BALB/c mice immunized with Anisakis extract in single or multiple doses and in mice orally infected with a larva. From animals immunized maximum responses were obtained with the multiple doses with an only IL-4 peak. Conversely, in the mice inoculated with a larva per os, the IL-4 levels showed two peaks of different rates.
Perteguer
M J
MJ
Departamento de Parasitología, Facultad de Farmacia, Universidad Complutense, Madrid, España.
Cuéllar
C
C
D000818:Animals; D017129:Anisakiasis / Q000276:immunology / Q000378:metabolism*; D017163:Anisakis / Q000276:immunology / Q000378:metabolism*; D000947:Antigens, Helminth / Q000276:immunology / Q000378:metabolism; D004797:Enzyme-Linked Immunosorbent Assay; D007074:Immunoglobulin G / Q000096:biosynthesis; D015847:Interleukin-4 / Q000096:biosynthesis* / Q000097:blood; D007814:Larva / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C
D000947:Antigens, Helminth; D007074:Immunoglobulin G; D015847:Interleukin-4