Connection topology dependence of synchronization of neural assemblies on class 1 and 2 excitability.
Two main classes of excitable neurons are analyzed in terms of connection topology and strength of the coupling in a network of neurons. In both cases, we measure the degree of synchronization and responsiveness of the neural assembly. Class 2 excitability presents a fast wave-like propagation of the activity pattern, strong frequency dependence on the connection topology and a good level of synchronization regardless of the topology. On the other hand, class 1 excitability shows a strong dependence of the wave propagation speed and the synchronization degree on the connection topology, in addition no frequency adaptation is observed. We conclude that both types of neural excitability endow the neural assembly with very different dynamical properties. Although, for simplicity reasons, no inhibition has been included in our study, the emergent properties described in this paper may help to determine the class of excitability underlying a neural assembly.
Lago-Fernández
L F
LF
ETS. de Ingeniería Informática, Universidad Autónoma de Madrid, Spain. luis.lago@ii.uam.es
Corbacho
F J
FJ
Huerta
R
R
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D001683:Biological Clocks / Q000502:physiology; D003344:Cortical Synchronization; D006801:Humans; D008959:Models, Neurological; D009415:Nerve Net / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*