Absorbable versus nonabsorbable membranes and bone grafts in the treatment of ligature-induced peri-implantitis defects in dogs: a histometric investigation.
The purpose of this study was to histometrically evaluate an absorbable collagen membrane (Bio-Gide) and a nonabsorbable polytetrafluoroethylene membrane (PTFE), associated with or without bone grafts, regarding "re-osseointegration" after treating ligature-induced peri-implantitis defects in dogs. All mandibular premolars were removed from five 2-year-old mongrel dogs. After 3 months of healing, 3 titanium implants were placed on each side of the mandible. Experimental peri-implantitis was induced with ligatures after abutment connection. Ligatures and abutments were removed after 1 month and the bone defects were randomly assigned to one of the following treatments; debridement alone (DB), debridement plus PTFE membrane associated with mineralized bone graft (Bio-Oss) (GBR+BG-I), debridement plus collagen membrane (Bio-Gide) associated with mineralized bone graft (GBR+BG-II), debridement plus PTFE membrane (GBR-I), debridement plus collagen membrane (GBR-II), or debridement plus mineralized-bone graft (BG). The dogs were sacrificed after 5 months. Data analysis did not reveal significant differences among the treatments regarding the percentage of bone-to-implant contact ("re-osseointegration") within the limits of the threads of the implant (P = .997). Thus, in the treatment of peri-implantitis, debridement alone as well as grafting alone had the same effect as did either membrane.
Nociti
F H
FH
Division of Periodontics, Dental School of Piracicaba, University of Campinas, São Paulo, Brazil. nociti@fop.unicamp.br
Machado
M A
MA
Stefani
C M
CM
Sallum
E A
EA
D020341:Absorbable Implants; D000704:Analysis of Variance; D000818:Animals; D001641:Bicuspid; D001672:Biocompatible Materials / Q000627:therapeutic use; D001857:Bone Matrix / Q000637:transplantation; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods; D003094:Collagen / Q000627:therapeutic use; D003646:Debridement; D000044:Dental Abutments; D015921:Dental Implants; D004195:Disease Models, Animal; D004285:Dogs; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008567:Membranes, Artificial; D008903:Minerals / Q000627:therapeutic use; D016348:Osseointegration; D010518:Periodontitis / Q000473:pathology / Q000601:surgery*; D011138:Polytetrafluoroethylene; D011897:Random Allocation; D013499:Surface Properties; D014025:Titanium; D016896:Treatment Outcome
C106416:Bio-Gide; C077540:Bio-Oss; D001672:Biocompatible Materials; D018786:Bone Substitutes; D015921:Dental Implants; D008567:Membranes, Artificial; D008903:Minerals; D011138:Polytetrafluoroethylene; D003094:Collagen; D014025:Titanium