title: Rigid registration of 3-D ultrasound with MR images: a new approach combining intensity and gradient information.
abstract: We present a new image-based technique to rigidly register intraoperative three-dimensional ultrasound (US) with preoperative magnetic resonance (MR) images. Automatic registration is achieved by maximization of a similarity measure which generalizes the correlation ratio, and whose novelty is to incorporate multivariate information from the MR data (intensity and gradient). In addition, the similarity measure is built upon a robust intensity-based distance measure, which makes it possible to handle a variety of US artifacts. A cross-validation study has been carried out using a number of phantom and clinical data. This indicates that the method is quite robust and that the worst registration errors are of the order of the MR image resolution.
authors.affiliation: INRIA-Projet Epidaure, Sophia Antipolis, France. aroche@sophia.inria.fr
authors.forename: A
authors.initials: A
authors.lastname: Roche
authors.forename: X
authors.initials: X
authors.lastname: Pennec
authors.forename: G
authors.initials: G
authors.lastname: Malandain
authors.forename: N
authors.initials: N
authors.lastname: Ayache
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology; D004453:Echoencephalography / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D007223:Infant; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures / Q000295:instrumentation; D019047:Phantoms, Imaging; D013997:Time Factors