title: Therapeutic drug monitoring in antituberculosis chemotherapy: clinical perspectives.
abstract: BACKGROUND
  Therapeutic drug monitoring (TDM) represents an area where multidisciplinary service is rendered for optimization of clinical care, through enabling maximum drug therapeutic efficacy and minimum drug toxicity. This is a recently developed field for antituberculosis chemotherapy. The other goals of TDM principally include study and management of pharmacokinetic drug-drug and drug-disease interactions as well as the evaluation of new fixed-dose combinations (FDC) developed for treatment of tuberculosis.
  
  
  CONCLUSIONS
  In the years to come, with the advancement in knowledge, technology and expertise, it is hoped that TDM, as a novel paradigm of care in tuberculosis, may gain expanding indications and reach a new horizon.
authors.affiliation: Tuberculosis and Chest Unit, Grantham Hospital, 125 Wong Chuk Hang Road, Aberdeen, Hong Kong, China.
authors.forename: W W
authors.initials: WW
authors.lastname: Yew
mesh_terms: D000995:Antitubercular Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use; D004347:Drug Interactions; D016903:Drug Monitoring / Q000379:methods*; D006801:Humans; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents