title: Optically Active Axially Chiral Anilide and Maleimide Derivatives as New Chiral Reagents: Synthesis and Application to Asymmetric Diels-Alder Reaction.
abstract: New axially chiral N-acryl-N-allyl-o-tert-butylanilide and N-(o-tert-butylphenyl)-2-methylmaleimide with high optical purity and definite absolute configurations were prepared from o-tert-butylaniline and (S)-O-acetyl lactic acid or (R)-2-methylsuccinic acid, respectively. Iodine- or Lewis acid-mediated asymmetric Diels-Alder reaction of these axially chiral compounds with various dienes proceeded with high endo and diastereofacial selectivity.
authors.affiliation: Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo 196, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Kitagawa
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Izawa
authors.forename: Kiyonobu
authors.initials: K
authors.lastname: Sato
authors.forename: Akira
authors.initials: A
authors.lastname: Dobashi
authors.forename: Takeo
authors.initials: T
authors.lastname: Taguchi
authors.forename: Motoo
authors.initials: M
authors.lastname: Shiro