title: Manoyl oxide alpha-arabinopyranoside and grindelic acid diterpenoids from Grindelia integrifolia.
abstract: Two new manoyl oxide-alpha-arabinopyranoside diterpenoids, 15-hydroxy-13-epi-manoyl oxide-14-O-alpha-L-arabinopyranoside (tarapacol-14-O-alpha-L-arabinopyranoside) (1) and 15-acetoxy-13-epi-manoyl oxide-14-O-alpha-L-arabinopyranoside (tarapacol-15-acetate-14-O-alpha-L-arabinopyranoside) (2), as well as a new grindelic acid derivative, 19-hydroxygrindelic acid (3), together with five known diterpenoids (tarapacol, tarapacanol A, grindelic acid, methyl grindeloate, 3beta-hydroxygrindelic acid, 4) were isolated from the aerial parts of Grindelia integrifolia. The structures of 1-3 were elucidated by spectral data analysis.
authors.affiliation: Department of Chemistry, Faculty of Science, El-Minia University, El-Minia 61519, Egypt. abdellaahmed@yahoo.com
authors.forename: A A
authors.initials: AA
authors.lastname: Ahmed
authors.forename: A A
authors.initials: AA
authors.lastname: Mahmoud
authors.forename: U M
authors.initials: UM
authors.lastname: Ahmed
authors.forename: A A
authors.initials: AA
authors.lastname: El-Bassuony
authors.forename: M H
authors.initials: MH
authors.lastname: Abd El-Razk
authors.forename: P W
authors.initials: PW
authors.lastname: Pare
authors.forename: J
authors.initials: J
authors.lastname: Karchesy
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
chemical_list: C440970:15-acetoxy-13-epi-manoyl oxide-14-O-alpha-L-arabinopyranoside; C440969:15-hydroxy-13-epi-manoyl oxide-14-O-arabinopyranoside; C440971:19-hydroxygrindelic acid; C440972:3-hydroxygrindelic acid; D004224:Diterpenes; D006027:Glycosides