title: Intracellular signalling. Key enzyme in leptin-induced anorexia.
authors.affiliation: Division of Metabolism, Endocrinology and Nutrition, University of Washington School of Medicine and Harborview Medical Center, Seattle, Washington 98104, USA.
authors.forename: K D
authors.initials: KD
authors.lastname: Niswender
authors.forename: G J
authors.initials: GJ
authors.lastname: Morton
authors.forename: W H
authors.initials: WH
authors.lastname: Stearns
authors.forename: C J
authors.initials: CJ
authors.lastname: Rhodes
authors.forename: M G
authors.initials: MG
authors.lastname: Myers
authors.forename: M W
authors.initials: MW
authors.lastname: Schwartz
mesh_terms: D000818:Animals; D000855:Anorexia / Q000139:chemically induced / Q000201:enzymology*; D002867:Chromones / Q000494:pharmacology; D004268:DNA-Binding Proteins / Q000378:metabolism; D004435:Eating / Q000187:drug effects; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D007031:Hypothalamus / Q000201:enzymology* / Q000378:metabolism; D007328:Insulin / Q000502:physiology; D020738:Leptin / Q000008:administration & dosage / Q000502:physiology*; D009025:Morpholines / Q000494:pharmacology; D009765:Obesity / Q000201:enzymology / Q000209:etiology; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D000081082:Phosphoinositide-3 Kinase Inhibitors; D051381:Rats; D050796:STAT3 Transcription Factor; D015398:Signal Transduction; D015534:Trans-Activators / Q000378:metabolism; D000521:alpha-MSH / Q000494:pharmacology
chemical_list: D002867:Chromones; D004268:DNA-Binding Proteins; D004791:Enzyme Inhibitors; D007328:Insulin; D020738:Leptin; D009025:Morpholines; D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D050796:STAT3 Transcription Factor; D015534:Trans-Activators; D000521:alpha-MSH; C494088:Stat3 protein, rat; C085911:2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one