Effect of defects on thermal denaturation of DNA oligomers.
Effect of defects on the melting profile of short heterogeneous DNA chains is calculated using the Peyrard-Bishop Hamiltonian. On-site potential on a defect site is represented by a potential that has only a short-range repulsion and a flat part without well of the Morse potential. Stacking energy between two neigbouring pairs involving a defect site is also modified. The results are found to be in good agreement with the experiments.
Singh
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Department of Physics, Banaras Hindu University, Varanasi 221 005, India.
Singh
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Y
D004247:DNA / Q000648:ultrastructure*; D006358:Hot Temperature; D006860:Hydrogen Bonding; D015233:Models, Statistical; D008962:Models, Theoretical; D009690:Nucleic Acid Conformation; D013696:Temperature; D013816:Thermodynamics
D004247:DNA