title: Tarsorrhaphy: clinical experience from a cornea practice.
abstract: OBJECTIVE
  To evaluate indications, success rate, and complications of tarsorrhaphy in a cohort of cornea and external disease patients.
  
  
  METHODS
  In this study, charts of patients who underwent tarsorrhaphies from January 1, 1995, to September 30, 2000, were retrospectively evaluated. Information reviewed included patient age and sex, indication for tarsorrhaphy, duration of signs and symptoms before tarsorrhaphy, time to epithelial healing after tarsorrhaphy, type of tarsorrhaphy (temporary/permanent), complications, timing of tarsorrhaphy removal, recurrence of signs and symptoms after complete or partial opening of the tarsorrhaphy, number of tarsorrhaphies needed to be replaced or extended, and duration of follow up.
  
  
  RESULTS
  Seventy-seven patients were included in this study. Indications for a tarsorrhaphy were persistent epithelial defects or other ocular surface problems associated with neurotrophic ulcers, penetrating keratoplasty (PK), postinfection, exposure keratopathy, surgery other than PK, dry eye syndrome, radiation keratopathy, ocular cicatricial pemphigoid, Stevens-Johnson syndrome, entropion, and application of tissue adhesive. The epithelial defects in 70 (90.9%) of the 77 eyes completely resolved. Overall, the mean duration of signs and symptoms before tarsorrhaphy was 89.8 +/- 27.8 days, and time-to-healing after tarsorrhaphy was 18.0 +/- 2.0 days. The difference between the duration of the signs and symptoms before tarsorrhaphy and time-to-healing after tarsorrhaphy was statistically significant ( p = 0.01). Of the 77 tarsorrhaphies, 24 (31.2%) were temporary and 53 (68.8%) were permanent. Complications after tarsorrhaphy included trichiasis, adhesion between upper and lower lids after tarsorrhaphy lysis, premature opening of the temporary tarsorrhaphy, pyogenic granuloma, and keloid formation of the eyelid.
  
  
  CONCLUSIONS
  Tarsorrhaphy is a very effective and safe procedure in the management of nonhealing epithelial defects and other surface problems, with a 90.9% success rate and only minor complications.
authors.affiliation: Cornea Service, Wills Eye Hospital, Department of Ophthalmology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: C B
authors.initials: CB
authors.lastname: Cosar
authors.forename: E J
authors.initials: EJ
authors.lastname: Cohen
authors.forename: C J
authors.initials: CJ
authors.lastname: Rapuano
authors.forename: M
authors.initials: M
authors.lastname: Maus
authors.forename: R P
authors.initials: RP
authors.lastname: Penne
authors.forename: J C
authors.initials: JC
authors.lastname: Flanagan
authors.forename: P R
authors.initials: PR
authors.lastname: Laibson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003316:Corneal Diseases / Q000601:surgery*; D005143:Eyelids / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D016896:Treatment Outcome; D014945:Wound Healing