title: Extramedullary plasmacytoma of the larynx: a case report.
abstract: Of head and neck malignancies extramedullary plasmacytoma occurs in less than 1% cases. It is the rarest primary laryngeal malignancy. A 65-year-old man presented with dry cough and breathlessness for last 6 months. Direct laryngoscopic examination showed a gray-white submucosal mass in the subglottic region. Histopathological examination showed presence of pseudostratified columnar epithelium with underlying stroma having mature and immature plasma cells. The cells were mono to bi-nucleated having eccentric nuclei and condensed spoke like chromatin. Few cells had centrally placed nuclei with small but conspicuous nucleoli. Some cells resembling Reed-Sternberg cells were also seen. The patient was successfully treated with primary radical radiotherapy and showed no signs of local recurrence after a 12-month follow-up.
authors.affiliation: Department of Radiation Therapy, The Gujarat Cancer and Research Institute, Ahmedabad.
authors.forename: G K
authors.initials: GK
authors.lastname: Maheshwari
authors.forename: H A
authors.initials: HA
authors.lastname: Baboo
authors.forename: U
authors.initials: U
authors.lastname: Gopal
authors.forename: N M
authors.initials: NM
authors.lastname: Shah
mesh_terms: D000368:Aged; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D010954:Plasmacytoma / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy