title: Persistence of secretory antiamoebic antibodies in patients with past invasive intestinal or hepatic amoebiasis.
abstract: In the present work, it was demonstrated that in amoebic dysentery and amoebic liver abscess patients, the secretory response is long-lasting (> 12 months); and 50% of amoebic dysentery patients developed circulating antiamoebic IgG in comparison with 100% of amoebic liver abscess individuals. A total of 83% of these individuals developed high levels of serum anti-Entamoeba histolytica IgA. However, only 10.4% of the dysentery patients showed this anti-E. histolytica antibody isotype in serum. There was no correlation between secretory and serum antiamoebic response, suggesting independent inductive and effector sites in both compartments.
authors.affiliation: Departamento de Medicina Experimental, Facultad de Medicina, UNAM, México DF, México.
authors.forename: O
authors.initials: O
authors.lastname: Valenzuela
authors.forename: F
authors.initials: F
authors.lastname: Ramos
authors.forename: P
authors.initials: P
authors.lastname: Morán
authors.forename: E
authors.initials: E
authors.lastname: González
authors.forename: A
authors.initials: A
authors.lastname: Valadez
authors.forename: A
authors.initials: A
authors.lastname: Gómez
authors.forename: E I
authors.initials: EI
authors.lastname: Melendro
authors.forename: M
authors.initials: M
authors.lastname: Ramiro
authors.forename: O
authors.initials: O
authors.lastname: Muñoz
authors.forename: C
authors.initials: C
authors.lastname: Ximénez
mesh_terms: D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D004404:Dysentery, Amebic / Q000276:immunology*; D004748:Entamoeba histolytica / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007071:Immunoglobulin A, Secretory / Q000032:analysis*; D007074:Immunoglobulin G / Q000097:blood; D008101:Liver Abscess, Amebic / Q000276:immunology*; D008875:Middle Aged; D012463:Saliva / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G