Multiple-channel microchips for high-throughput DNA analysis by capillary electrophoresis.
Capillary electrophoresis on microfabricated multiple-channel chips has great potential for high-throughput analysis. This review focuses on multiple-channel chips used for high-throughput DNA analysis. It covers progress in the design and fabrication of multiple-channel chips and detection schemes used on these chips. Applications are concentrated on DNA fragment sizing, genotyping, and sequencing.
Gao
Q
Q
Molecular Dynamics, Sunnyvale, CA 94085, USA.
Shi
Y
Y
Liu
S
S
D000818:Animals; D004247:DNA / Q000032:analysis*; D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000592:standards; D004867:Equipment Design; D005838:Genotype; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation* / Q000379:methods; D017422:Sequence Analysis, DNA
D004247:DNA