title: A tandem Michael addition ring-closure route to the metabotropic receptor ligand alpha-(hydroxymethyl)glutamic acid and its gamma-alkylated derivatives.
authors.affiliation: Georgetown University Medical Center, Drug Discovery Program, 3970 Reservoir Road NW, Washington, DC 20007-2197, USA.
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: J L
authors.initials: JL
authors.lastname: Flippen-Anderson
authors.forename: A P
authors.initials: AP
authors.lastname: Kozikowski
mesh_terms: D003460:Crystallization; D003500:Cyclization; D005971:Glutamates / Q000138:chemical synthesis*; D008024:Ligands; D015394:Molecular Structure; D018094:Receptors, Metabotropic Glutamate / Q000819:agonists* / Q000037:antagonists & inhibitors
chemical_list: C449086:(hydroxymethyl)glutamic acid; D005971:Glutamates; D008024:Ligands; D018094:Receptors, Metabotropic Glutamate; C025648:2-methylglutamic acid; C011859:hydroxyglutamic acid