About some physical mechanisms of statistics of radiation-induced effects formation and non-linear cell response in low dose area.
A new cascade-stochastic approach to solve the direct and inverse problems of radiation-induced effect statistics in track biodetectors is presented in this paper. The analysis of the experimental data has made it possible to establish a non-linear nature of the "dose-effect" dependence in low dose area. For the first time, a new determination of the relative biological efficiency and quality coefficient of ionizing radiation in area of low doses are proposed.
Rusov
V
V
Department of Theoretical and Experimental Nuclear Physics, Odessa Polytechnic University, Shevchenko av I, Odessa 65044, Ukraine. siiis@e.net.ua
Zelentsova
T
T
Melentchuk
I
I
Beglaryan
M
M
D002467:Cell Nucleus / Q000528:radiation effects*; D002843:Chromatin / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D018499:Linear Energy Transfer; D008214:Lymphocytes / Q000528:radiation effects*; D048629:Micronuclei, Chromosome-Defective; D015233:Models, Statistical; D017711:Nonlinear Dynamics; D011829:Radiation Dosage; D012062:Relative Biological Effectiveness; D013269:Stochastic Processes
D002843:Chromatin