[The status of coagulation and lipid blood spectrum in patients with peptic ulcer complicated by ischemic heart disease].
Coagulative blood activity, fibrinogen and lipid spectrum were examined in 130 patients with gastroduodenal pathology. Increase of common blood lipids in 2-3 times was demonstrated in these patients as well as increase of the threeglycerides, blood fibrinogen and cholesterol reduce of high density lipoproteids. Hyperlipidemia was accompanied with blood hypercoagulation. Hypercoagulation was demonstrated in the 1st-2nd-3rd stages of blood coagulation. The common constant of blood coagulation was reduced in 2 times, elasticity of blood clot and coagulation index were increased in 2 times. Fibrinolysis is depressed and homostasis is activated in the patients with peptic ulcer with heart ishemic disease combination. The authors had considered that there is a pathogenetic connection between lipid intracells content and fibrinolytic blood system, as well as intercommunication of hemocoagulation and heart ishemic disease heaviness.
Zvenigorodskaia
L A
LA
Nilova
T V
TV
D000328:Adult; D000368:Aged; D001778:Blood Coagulation Disorders / Q000150:complications*; D008076:Cholesterol, HDL / Q000097:blood; D002908:Chronic Disease; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis / Q000502:physiology; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000150:complications*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood / Q000150:complications*; D010437:Peptic Ulcer / Q000097:blood / Q000150:complications*; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D014280:Triglycerides; D005340:Fibrinogen