title: Intracrevicular application of 0.3% Flurbiprofen gel and 0.3% Triclosan gel as anti inflammatory agent. A comparative clinical study.
abstract: This study compared the anti-inflammatory efficacy of Triclosan and Flurbiprofen in a gel form on clinical parameters of moderate gingivitis cases. The study comprised of 100 sites from 16 volunteers and used split mouth technique. 0.3% Triclosan/0.3% Flurbiprofen gels applied intracrevicularly once daily for one week. Clinical parameters like Plaque index, Gingival index and Bleeding index scores were recorded at 0 day, 4th day and 8th day. The obtained results showed significant reductions in clinical parameters from baseline to 8th day. This indicates local delivery of 0.3% Triclosan/0.3% Flurbiprofen gel can be used as an anti-inflammatory agents either alone or as an adjunct to scaling in periodontal therapy.
authors.affiliation: Department of Periodontics, College of Dental Sciences and Bapuji Dental College, Davangere, India.
authors.forename: D K
authors.initials: DK
authors.lastname: Suresh
authors.forename: K L
authors.initials: KL
authors.lastname: Vandana
authors.forename: D S
authors.initials: DS
authors.lastname: Mehta
mesh_terms: D000293:Adolescent; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D003774:Dental Plaque Index; D005260:Female; D005480:Flurbiprofen / Q000008:administration & dosage*; D005782:Gels; D005881:Gingiva; D005891:Gingivitis / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D008297:Male; D010512:Periodontal Index; D014260:Triclosan / Q000008:administration & dosage*
chemical_list: D000891:Anti-Infective Agents, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005782:Gels; D014260:Triclosan; D005480:Flurbiprofen