High temporal resolution dynamic contrast MRI in a high risk group for placenta accreta.
Antenatal diagnosis of placenta accreta with MR is not easy even now because T2-weighted images (T2WI) cannot differentiate chorionic villi from decidua basalis. We performed dynamic contrast MRI to study whether trophoblastic villi could be separately demonstrated from the decidua basalis, and whether the contrast resolution between the placenta and myometrium could improve compared to T2WI. Six pregnant women with prior cesarean section were examined at 34-38 gestational weeks. Sagittal T2-weighted images with fast spin echo sequences and dynamic contrast studies with fast field echo sequence every 10-14 s after contrast injection were performed. We analyzed the enhancing pattern of the placenta and compared the contrast between placenta and myometrium. We reviewed medical records to identify complications during the placental delivery and the complications of their newborns. In the early phase after contrast enhancement, multiple foci of the strong lobular enhancement were observed in all cases. Other parts of placenta were slowly but strongly enhanced following them. We speculated that the former corresponded to intervillous space and the latter decidua basalis. The contrast between placenta and myometrium tended to be distinct near the inner cervical os on both T2WI and dynamic contrast study. On the other hand, it was indistinct in the upper part of the uterine body on T2WI despite it was clearly demonstrated on dynamic contrast study. The placentae were delivered without any complication in all cases. Although two neonates showed fetal distress, none of the infant remained any sequelae at the time of the discharge. The other four were well although one of them complicated with meconium staining. As dynamic contrast MRI can differentiate chorionic villi and decidua basalis, and can provide excellent contrast between placenta and myometrium at anywhere within the uterus, it may be a promising technique for antepartum diagnosis of the placenta accreta.
Tanaka
Y O
YO
Department of Radiology, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan. ytanaka@md.tsukuba.ac.jp
Sohda
S
S
Shigemitsu
S
S
Niitsu
M
M
Itai
Y
Y
D002824:Chorionic Villi / Q000473:pathology; D003656:Decidua / Q000473:pathology; D005260:Female; D005865:Gestational Age; D006801:Humans; D007089:Image Enhancement; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D009215:Myometrium / Q000473:pathology; D010920:Placenta / Q000473:pathology; D010921:Placenta Accreta / Q000175:diagnosis*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014327:Trophoblasts / Q000473:pathology