title: A rare cause of intracranial hemorrhage: factor X deficiency.
abstract: Congenital factor X deficiency is a rare inherited coagulation disorder, characterized by prolonged prothrombin time and partial thromboplastin time. For the definite diagnosis, specific factor X level should be investigated. We describe a patient with factor X deficiency who had intracranial hemorrhage. Hematologic tests showed prolonged prothrombin time, partial thromboplastin time, and a factor X level of 5%. The patient's hemorrhage resolved with fresh frozen plasma replacement. In this article, we discuss the clinical features and management of factor X deficiency.
authors.affiliation: Department of Pediatric Emergency Istanbul University Institute of Child Health, Istanbul, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Citak
authors.forename: R
authors.initials: R
authors.lastname: Uçsel
authors.forename: M
authors.initials: M
authors.lastname: Karaböcüoglu
authors.forename: A
authors.initials: A
authors.lastname: Unüvar
authors.forename: N
authors.initials: N
authors.lastname: Uzel
mesh_terms: D003241:Consanguinity; D005171:Factor X Deficiency / Q000097:blood / Q000150:complications* / Q000151:congenital / Q000628:therapy; D006801:Humans; D007223:Infant; D020300:Intracranial Hemorrhages / Q000097:blood / Q000209:etiology*; D008297:Male; D010314:Partial Thromboplastin Time; D011517:Prothrombin Time