Sequoiatones C-f, constituents of the redwood endophyte Aspergillus parasiticus.
Aspergillus parasiticus, a fungal isolate from a coast redwood tree (Sequoia sempervirens), has been shown to produce four new compounds, sequoiatones C-F (1-4). The structures of these compounds, all of which are cytotoxic to brine shrimp, were deduced by spectral analysis.
Stierle
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Department of Chemistry and Geochemistry, Montana Tech of the University of Montana, Butte, MT 59701, USA. astierle@mtech.edu
Stierle
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Bugni
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D000818:Animals; D001156:Artemia / Q000187:drug effects; D001230:Aspergillus / Q000737:chemistry*; D002140:California; D032462:Cycadopsida / Q000737:chemistry*; D006574:Heterocyclic Compounds, 2-Ring / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship; D018675:Toxicity Tests
D006574:Heterocyclic Compounds, 2-Ring; C440689:sequoiatone C; C440691:sequoiatone D; C440692:sequoiatone E; C440690:sequoiatone F