title: Analgesic/abortive overuse and misuse in chronic daily headache.
abstract: The frequent use (> 15 times/month) of medication for the treatment of acute migraine attacks may cause medication overuse headache. This kind of headache can be caused by the intake of combination analgesics, opioids, ergot alkaloids, and triptans. The delay between first intake and daily headache is shortest for triptans (1 to 2 years), longer for ergots (3 years), and longest for analgesics (5 years). Treatment includes drug withdrawal followed by structured acute therapy and initiation of migraine prophylactic treatment.
authors.affiliation: Department of Neurology, University Essen, Hufelandstr. 55, Essen 45122, Germany. h.diener@uni-essen.de
authors.forename: H C
authors.initials: HC
authors.lastname: Diener
authors.forename: Z
authors.initials: Z
authors.lastname: Katasarva
mesh_terms: D000700:Analgesics / Q000009:adverse effects* / Q000627:therapeutic use; D020773:Headache Disorders / Q000139:chemically induced* / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D019966:Substance-Related Disorders / Q000503:physiopathology / Q000628:therapy*
chemical_list: D000700:Analgesics