title: Effects of mirtazapine on the levels of exogenous histamine in the plasma of the cat.
abstract: Effects of the antidepressant drug mirtazapine on plasma levels and on the kinetics of injected histamine were studied in the cat. In the dose of 0.6 mg/kg mirtazapine did not affect the characteristics of the elimination curve of histamine. The higher dose of mirtazapine (1.2 mg/kg) prevented the increase of plasma histamine levels.
authors.affiliation: Department of Pharmacology and Experimental Toxicology, Medical Faculty, Ljubljana, Slovenia.
authors.forename: M
authors.initials: M
authors.lastname: Arko
authors.forename: T I
authors.initials: TI
authors.lastname: Florjanc
mesh_terms: D000818:Animals; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology; D002415:Cats; D005260:Female; D006632:Histamine / Q000097:blood / Q000493:pharmacokinetics*; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D008803:Mianserin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D000078785:Mirtazapine
chemical_list: D000929:Antidepressive Agents, Tricyclic; D006634:Histamine H1 Antagonists; D008803:Mianserin; D006632:Histamine; D000078785:Mirtazapine