title: Deblurring subject to nonnegativity constraints when known functions are present with application to object-constrained computerized tomography.
abstract: The reconstruction of tomographic images is often treated as a linear deblurring problem. When a high-density, man-made metal object is present somewhere in the image field, it is a deblurring problem in which the unknown function has a component that is known except for some location and orientation parameters. We first address general linear deblurring problems in which a known function having unknown parameters is present. We then show how the resulting iterative solution can be applied to tomographic imaging in the presence of man-made foreign objects, and we apply the result, in particular, to X-ray computed tomography imaging used in support of brachytherapy treatment of advanced cervical cancer.
authors.affiliation: Department of Electrical Engineering, Washington University, St. Louis, MO 63130-4899, USA. dls@ee.wustl.edu
authors.forename: D L
authors.initials: DL
authors.lastname: Snyder
authors.forename: J A
authors.initials: JA
authors.lastname: O'Sullivan
authors.forename: B R
authors.initials: BR
authors.lastname: Whiting
authors.forename: R J
authors.initials: RJ
authors.lastname: Murphy
authors.forename: J
authors.initials: J
authors.lastname: Benac
authors.forename: J A
authors.initials: JA
authors.lastname: Cataldo
authors.forename: D G
authors.initials: DG
authors.lastname: Politte
authors.forename: J F
authors.initials: JF
authors.lastname: Williamson
mesh_terms: D016477:Artifacts; D001918:Brachytherapy; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D019047:Phantoms, Imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy