title: Coagulase-negative staphylococci as a cause of infections related to intravascular prosthetic devices: limitations of present therapy.
abstract: Coagulase-negative staphylococci (CNS) are an important cause of catheter-related bloodstream infections. This review will shed light on the pathogenesis related to biofilm formation, and will discuss antimicrobial susceptibility of CNS to older and newer antibiotics, as well as therapeutic options.
authors.affiliation: University Medical Center St Radboud, Department of Medical Microbiology, Nijmegen, The Netherlands. t.schulin@mmb.azn.nl
authors.forename: T
authors.initials: T
authors.lastname: Schulin
authors.forename: A
authors.initials: A
authors.lastname: Voss
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D016470:Bacteremia / Q000382:microbiology; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003030:Coagulase / Q000378:metabolism; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D016459:Prosthesis-Related Infections / Q000188:drug therapy* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013210:Staphylococcus / Q000187:drug effects* / Q000201:enzymology
chemical_list: D000900:Anti-Bacterial Agents; D003030:Coagulase