The end of the beginning for pluripotent stem cells.
Pluripotent stem cells can be expanded seemingly indefinitely in culture, maintain a normal karyotype and have the potential to generate any cell type in the body. As such they represent an incredible resource for the repair of diseased or damaged tissues in our bodies. These cells also promise to open a new window into the embryonic development of our species.
Donovan
P J
PJ
Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. pdonovan@lac.jci.tju.edu
Gearhart
J
J
D000818:Animals; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D002460:Cell Line; D003257:Consumer Product Safety; D004622:Embryo, Mammalian / Q000166:cytology; D005544:Forecasting; D006801:Humans; D051379:Mice; D023421:Models, Animal; D033581:Stem Cell Transplantation; D013234:Stem Cells