Uraemic gangrene syndrome: is parathyroidectomy always necessary?
This report presents a case of uraemic gangrene syndrome with multiple ulcerations and calcium (Ca) deposits in the vessel walls. High-dosage oral calcium carbonate (CaCO3) treatment alone resulted in rapid wound healing with decreased serum phosphorus (P), Ca x P product and parathormone and only slightly increased Ca levels. We suggest that this should be the first choice of treatment in such cases because positive clinical response can achieve symptom-free status for the patient until kidney transplantation, thus making parathyroidectomy unnecessary.
Scharrer
K
K
Department of Dermatology, Central Military Hospital, Budapest, Hungary.
Mako
J
J
Vajda
A
A
Baló-Bangat
J M
JM
D000328:Adult; D002119:Calcium Carbonate / Q000008:administration & dosage / Q000627:therapeutic use*; D005734:Gangrene / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000188:drug therapy* / Q000601:surgery*; D008297:Male; D016105:Parathyroidectomy; D013577:Syndrome; D014511:Uremia / Q000150:complications*
D002119:Calcium Carbonate