Palladium-catalyzed coupling of two alkynes and an alkenyl iodide: formation of pentasubstituted fulvenes.
[reaction: see text]. Disubstituted alkynes reacted with alkenyl iodide in the presence of a catalytic amount of Pd(OAc)2 and Ag2CO3 to give pentasubstituted fulvene derivatives in excellent yields. Other Ag salts such as AgNO3, AgBF4, and AgOTf are not effective, whereas a combination of AgNO3 and K2CO3 has a remarkable effect on the formation of fulvene.
Kotora
M
M
Catalysis Research Center and Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo 060 -0811, Japan.
Matsumura
H
H
Gao
G
G
Takahashi
T
T