AAS and AES determination of furaltadone, methadone and trazodone in pharmaceutical formulations.
Ion-associate complexes of furaltadone, methadone and trazodone hydrochlorides with [Cd(SCN)(4)](2-) and [Zn(SCN)(4)](2-) were precipitated and the excess unreacted cadmium or zinc complex was determined. A new method using atomic emission and atomic absorption spectrometry for the determination of the above drugs in pure solutions and in pharmaceutical preparations is given. The drugs can be determined by the affort method in the ranges 7.2-72.16, 6.9-69.18 and 8.1-81.6 microg/ml solutions of the three drugs, respectively.
Khalil
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Department of Chemistry, Faculty of Science, Cairo University, Fayoum Branch, Riyadh 11491, Fayoum, Egypt. s_khalil_99@yahoo.com
El-Ries
M A
MA
D000892:Anti-Infective Agents, Urinary / Q000032:analysis; D000996:Antitussive Agents / Q000032:analysis; D019187:Cadmium Compounds; D002626:Chemistry, Pharmaceutical; D008691:Methadone / Q000032:analysis*; D009581:Nitrofurans / Q000032:analysis*; D023303:Oxazolidinones / Q000032:analysis*; D015203:Reproducibility of Results; D017367:Selective Serotonin Reuptake Inhibitors / Q000032:analysis; D012996:Solutions; D013054:Spectrophotometry, Atomic; D014196:Trazodone / Q000032:analysis*; D017967:Zinc Compounds
D000892:Anti-Infective Agents, Urinary; D000996:Antitussive Agents; D019187:Cadmium Compounds; D008691:Methadone; D009581:Nitrofurans; D023303:Oxazolidinones; D017367:Selective Serotonin Reuptake Inhibitors; D012996:Solutions; D014196:Trazodone; D017967:Zinc Compounds; C007795:furaltadon