title: The Kapakahines, Cyclic Peptides from the Marine Sponge Cribrochalina olemda.
abstract: Four cyclic peptides, kapakahines A-D, were isolated from the marine sponge Cribrochalina olemda. Their structures including complete stereochemistry were elucidated by spectral analysis and chemical degradation. The unique structural feature of these peptides is the lack of an amide linkage between two tryptophan residues. Instead the ring is closed by a bond from the indole nitrogen of Trp-1 to the beta-carbon of Trp-2.
authors.affiliation: Harbor Branch Oceanographic Institution, Inc.,(2) 5600 North U.S. 1, Fort Pierce, Florida 34936.
authors.forename: Bryan K. S.
authors.initials: BK
authors.lastname: Yeung
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Nakao
authors.forename: Robin B.
authors.initials: RB
authors.lastname: Kinnel
authors.forename: John R.
authors.initials: JR
authors.lastname: Carney
authors.forename: Wesley Y.
authors.initials: WY
authors.lastname: Yoshida
authors.forename: Paul J.
authors.initials: PJ
authors.lastname: Scheuer
authors.forename: Michelle
authors.initials: M
authors.lastname: Kelly-Borges