title: Successful en bloc resection of a large superficial gastric cancer by using sodium hyaluronate and electrocautery incision forceps.
abstract: BACKGROUND
  The advisability of endoscopic mucosal resection (EMR) for treatment of large superficial gastric cancers has been challenged. For more reliable en bloc resection, a new method of EMR was developed that uses a viscous substance, sodium hyaluronate, and two newly designed devices.
  
  
  METHODS
  A large superficial gastric cancer was treated with this new EMR technique. Sodium hyaluronate was injected into the submucosa and mucosal incisions were made with a needle-knife. The newly developed incision forceps and flat-ended transparent hood were used for submucosal incisions.
  
  
  RESULTS
  The large cancer was successfully resected endoscopically as a single piece of mucosa 6 cm in diameter without complication. Histopathologic evaluation of the specimen confirmed that the resection was curative.
  
  
  CONCLUSIONS
  EMR with sodium hyaluronate along with two new devices may be a reliable method for en bloc resection of large superficial gastric lesions.
authors.affiliation: Department of Gastroenterology, Jichi Medical School, Tochigi, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Sekine
authors.forename: T
authors.initials: T
authors.lastname: Higashizawa
authors.forename: K
authors.initials: K
authors.lastname: Kihira
authors.forename: Y
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Y
authors.initials: Y
authors.lastname: Hosoya
authors.forename: K
authors.initials: K
authors.lastname: Ido
authors.forename: K
authors.initials: K
authors.lastname: Saito
authors.forename: K
authors.initials: K
authors.lastname: Sugano
mesh_terms: D000368:Aged; D004564:Electrocoagulation / Q000295:instrumentation*; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage; D008297:Male; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*
chemical_list: D006820:Hyaluronic Acid