Preliminary evaluation of the hypoglycemic effect of some Brazilian medicinal plants.
The hypoglycemic effect of five Brazilian medicinal plants (Epidendrum monsenii, Marrubium vulgare, Rheedia gardneriana, Rubus imperialis and Wedelia paludosa) was studied on alloxan-induced diabetic rats. The extract of these plants was intragastrically administered to diabetic rats. The results showed that all plants studied (except R. gardneriana) significantly lowered the blood glucose. These results suggest that these four medicinal plants could be an adjuvant agent in the treatment of diabetes mellitus.
Novaes
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AP
Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), Centro de Ensino Superior em Ciências da Saúde (CCS), Universidade do Vale do Itajaí, UNIVALI, Rua Uruguai 458, 88302-202, Itajaí, SC, Brazil.
Rossi
C
C
Poffo
C
C
Pretti Júnior
E
E
Oliveira
A E
AE
Schlemper
V
V
Niero
R
R
Cechinel-Filho
V
V
Bürger
C
C
D000496:Alloxan; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001938:Brazil; D002855:Chromatography, Thin Layer; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000496:Alloxan