title: Ortho-Directed Lithiation of omega-Phenoxy Alcohols.
abstract: omega-Phenoxy alcohols, PhO(CH(2))(n)()OH (n = 2-7), have been subjected to metalation with 2 equiv of n-butyllithium in tetrahydrofuran/methylcyclohexane solvent. Reaction of the resulting lithiated compounds with carbon dioxide (n = 2-7), benzaldehyde (n = 2-6), benzophenone (n = 2, 3), dimethylformamide (n = 2), ethyl formate (n = 2), and chlorodiphenylphosphine (n = 3) afforded the corresponding ortho-substituted hydroxyalkoxybenzenes in yields ranging from 45 to 83%. The synthesis is also reported of five new bis[o-(omega-hydroxyalkoxy)phenyl]mercury compounds (n = 2-6), four crystal structures of which have been determined.
authors.affiliation: Institute of Materials Science, NCSR "Democritos", 153 10 Aghia Paraskevi Attikis, Greece.
authors.forename: Constantinos S.
authors.initials: CS
authors.lastname: Salteris
authors.forename: Ioannis D.
authors.initials: ID
authors.lastname: Kostas
authors.forename: Maria
authors.initials: M
authors.lastname: Micha-Screttas
authors.forename: George A.
authors.initials: GA
authors.lastname: Heropoulos
authors.forename: Constantinos G.
authors.initials: CG
authors.lastname: Screttas
authors.forename: Aris
authors.initials: A
authors.lastname: Terzis