title: Role of gammadelta T cells in protecting normal airway function.
abstract: Since their discovery 15 years ago, the role of gammadelta T cells has remained somewhat elusive. Responses of gammadelta T cells have been found in numerous infectious and non-infectious diseases. New evidence points to gammadelta T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of gammadelta T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.
authors.affiliation: National Jewish Medical and Research Center, Denver, Colorado 80206, USA.
authors.forename: W K
authors.initials: WK
authors.lastname: Born
authors.forename: M
authors.initials: M
authors.lastname: Lahn
authors.forename: K
authors.initials: K
authors.lastname: Takeda
authors.forename: A
authors.initials: A
authors.lastname: Kanehiro
authors.forename: R L
authors.initials: RL
authors.lastname: O'Brien
authors.forename: E W
authors.initials: EW
authors.lastname: Gelfand
mesh_terms: D000818:Animals; D007109:Immunity; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000378:metabolism*; D012137:Respiratory System / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000502:physiology; D013601:T-Lymphocytes / Q000502:physiology*
chemical_list: D016692:Receptors, Antigen, T-Cell, gamma-delta