title: Sex differences in length of survival with malignant astrocytoma, but not with glioblastoma.
abstract: In a retrospective analysis based on a malignant glioma databank, we describe effects of age, sex and diagnosis upon survival in patients with malignant cerebral glioma with a pre-treatment Karnofsky-index of 60 or more. All patients had been treated with 55-60Gy radiotherapy and nitrosurea-based adjuvant chemotherapy. We found an age-dependent sex effect upon survival in grade III astrocytoma patients, but not with glioblastoma.
authors.affiliation: Department of Neurology, Otto-von-Guericke-University, Magdeburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Diete
authors.forename: T
authors.initials: T
authors.lastname: Treuheit
authors.forename: K
authors.initials: K
authors.lastname: Dietzmann
authors.forename: U
authors.initials: U
authors.lastname: Schmidt
authors.forename: C W
authors.initials: CW
authors.lastname: Wallesch
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001254:Astrocytoma / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D001932:Brain Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D005260:Female; D005909:Glioblastoma / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012737:Sex Factors; D015996:Survival Rate