title: [Transeptal steroids in necrotizing scleritis].
abstract: OBJECTIVE
  To analyze the efficacy of transeptal corticosteroid injections in necrotizing scleritis as additional treatment to systemic immunosuppressors.
  
  
  METHODS
  Eleven patients with necrotizing scleritis treated with systemic immunosuppressors received transeptal corticosteroid injections during periods of active inflammation.
  
  
  RESULTS
  Transeptal corticosteroid injections in addition to systemic immunosuppressors halted active imflammation in 10 of 11 patients with necrotizing scleritis, showing few side effects. Because of that, there was no need to increase dosage nor to switch systemic immunosuppressors. There was no evidence of scleral perforation, scleral thinning and no cases of staphyloma were observed.
  
  
  CONCLUSIONS
  Systemic immunosuppressors remain as the first choice treatment for necrotizing scleritis; however, transeptal corticosteroid injections may be helpful as additional treatment during periods of active inflammation.
authors.affiliation: Servicio de Oftalmología, Unidad de Inmunología Ocular y Uveítis, Hospital Clínico y Provincial de Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Sainz De La Maza Serra
authors.forename: J
authors.initials: J
authors.lastname: Folch Ramos
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001379:Azathioprine / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007267:Injections / Q000379:methods; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D015423:Scleritis / Q000188:drug therapy*
chemical_list: D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D001379:Azathioprine; D011241:Prednisone; D008727:Methotrexate