Kaposi's sarcoma and cytomegaloviral ileocolitis complicating long-standing Crohn's disease in an HIV-negative patient.
A 67-yr-old woman with a 25-yr history of Crohn's disease, maintained on near-continuous corticosteroids (prednisone 10 mg daily) over a 6-yr period, underwent ileocolic resection for obstruction. Pathology revealed Crohn's disease, multiple nodules of Kaposi's sarcoma, and cytomegalic inclusion bodies with confirmation of cytomegalovirus by shell vial immunofluorescence. Testing for HIV serum antibody has been repeatedly negative. Crohn's disease, Kaposi's sarcoma, and cytomegalovirus have been clinically in remission for 5 yr.
Cohen
R L
RL
Department of Medicine, Veterans Administration Medical Center, New York, New York, USA.
Tepper
R E
RE
Urmacher
C
C
Katz
S
S
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003424:Crohn Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D018023:HIV Seronegativity; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D012514:Sarcoma, Kaposi / Q000150:complications* / Q000175:diagnosis
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011241:Prednisone