Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency.
Haemolytic crisis in glucose-6-phosphate dehydrogenase deficient individuals following topical application of henna occurred in four children: a female neonate (haemoglobin 50 g/l, serum bilirubin 700 micromol/l), who recovered after exchange transfusion; a male infant (haemoglobin 28 g/l) who died despite transfusion; and two preschool children (haemoglobin 40 and 41 g/l respectively).
Raupp
P
P
Department of Paediatrics, Tawam Hospital, Al Ain, United Arab Emirates. raupppeter@hotmail.com
Hassan
J A
JA
Varughese
M
M
Kristiansson
B
B
D000208:Acute Disease; D002675:Child, Preschool; D004396:Coloring Agents / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D005953:Glycogen Storage Disease Type I / Q000097:blood*; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009285:Naphthoquinones / Q000009:adverse effects*
D004396:Coloring Agents; D009285:Naphthoquinones; C005090:lawsone