title: Ringer-Lactate solution versus isotonic saline solution on mucociliary function after nasal septal surgery.
abstract: Irrigation with isotonic saline is one of the most frequently used solutions after nasal surgery. However, the effect of saline solutions on mucociliary clearance is not well known. In a previous study, it was found that isotonic saline solution had a negative effect on ciliary beat frequency but Ringer-Locke solution had no effect in vitro. In this study we compared the effects of Ringer-Lactate solution and isotonic saline solution on mucociliary transport time before, and after, nasal septal surgery in patients with nasal septal deviation. We found that patients who used Ringer-Lactate solution as irrigation after surgery had a significantly better mucociliary transport time than the patients using isotonic saline solution (p < 0.05). In conclusion, it is better to use Ringer-Lactate solution instead of 0.9 per cent saline solution for nasal irrigation.
authors.affiliation: Department of Otorhinolaryngology-- Head and Neck Surgery, Mersin University, Faculty of Medicine, Mersin, Turkey. muunal@hotmail.com
authors.forename: M
authors.initials: M
authors.lastname: Unal
authors.forename: K
authors.initials: K
authors.lastname: Görür
authors.forename: C
authors.initials: C
authors.lastname: Ozcan
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007552:Isotonic Solutions; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance; D009300:Nasal Septum / Q000601:surgery*; D009667:Nose Deformities, Acquired / Q000503:physiopathology / Q000601:surgery*; D011184:Postoperative Period; D000077325:Ringer's Lactate; D012439:Saccharin; D012965:Sodium Chloride; D007507:Therapeutic Irrigation
chemical_list: D007552:Isotonic Solutions; D000077325:Ringer's Lactate; D012965:Sodium Chloride; D012439:Saccharin