title: Pyoderma vegetans.
abstract: BACKGROUND
  Pyoderma vegetans is a rare condition that is clinically characterized by large verrucous plaques with elevated borders and multiple pustules. The etiology of this disorder remains unknown.
  
  
  OBJECTIVE
  We describe a 24-year-old woman with rapidly evolving pyoderma vegetans. Our patient had the unique additional findings of a highly elevated serum IgE level and a history of hidradenitis suppurativa.
  
  
  CONCLUSIONS
  Pyoderma vegetans is diagnosed on clinical and histological criteria. Differentiation must be made from disorders such as pyoderma gangrenosum, Sweet's syndrome, and deep fungal infections. We illustrate a case of pyoderma vegetans and review the literature on this rare disorder. Clinical and histological criteria for diagnosis are presented, as well as differentiation from some mimicking disorders.
authors.affiliation: Department of Dermatology, New Jersey Medical School, Newark, New Jersey 07103-2714, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Papadopoulos
authors.forename: R A
authors.initials: RA
authors.lastname: Schwartz
authors.forename: R
authors.initials: R
authors.lastname: Kapila
authors.forename: J A
authors.initials: JA
authors.lastname: Samady
authors.forename: Z
authors.initials: Z
authors.lastname: Ruszczak
authors.forename: B K
authors.initials: BK
authors.lastname: Rao
authors.forename: W C
authors.initials: WC
authors.lastname: Lambert
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D017497:Hidradenitis Suppurativa / Q000150:complications; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D011711:Pyoderma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
chemical_list: D007073:Immunoglobulin E