title: A Novel Asymmetric Route to the 1,3-Disubstituted Tetrahydroisoquinoline, (-)-Argemonine.
abstract: Chiral bicyclic lactam 13 was converted to the natural product (-)-argemonine 9 in six steps. This novel route to argemonine represents a general strategy for the preparation of chiral 1,3-disubstituted tetrahydroisoquinolines.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523.
authors.forename: Michael J.
authors.initials: MJ
authors.lastname: Munchhof
authors.forename: A. I.
authors.initials: AI
authors.lastname: Meyers