title: [Lateralizing and localizing signs and symptoms of epileptic seizures: significance and application in clinical practice].
abstract: This report reviews the lateralising and localising signs of epileptic seizures in respect to the differential diagnosis of epilepsy. The lateralising value of epileptic signs and symptoms can frequently be derived from the neuroanatomy. Focal clonic, focal tonic, and versive seizures as well as ictal unilateral dystonia are associated with a seizure onset zone in the contralateral hemisphere. Postictal nose wiping is performed with the hand ipsilateral to the epileptogenic zone. Similarly, unilateral blinking points to an ipsilateral seizure onset. Automatisms with preserved consciousness, ictal speech, and vomiting correlate to an epileptogenic zone in the non-dominant hemisphere, while postictal dysphasia is produced by seizures arising from the dominant hemisphere. Lateralising and localising signs and symptoms of epileptic seizures are of great help in the differential diagnosis of epilepsy from the first diagnosis of epileptic events to presurgical video-EEG monitoring.
authors.affiliation: Interdisziplinäres Epilepsie-Zentrum am Klinikum, Philipps-Universität Marburg, Klinik für Neurologie, Rudolf-Bultmann-Strasse 8, 35033 Marburg. rosenow@mailer.uni-marburg.de
authors.forename: F
authors.initials: F
authors.lastname: Rosenow
authors.forename: H M
authors.initials: HM
authors.lastname: Hamer
authors.forename: S
authors.initials: S
authors.lastname: Knake
authors.forename: N
authors.initials: N
authors.lastname: Katsarou
authors.forename: B
authors.initials: B
authors.lastname: Fritsch
authors.forename: W H
authors.initials: WH
authors.lastname: Oertel
authors.forename: K
authors.initials: K
authors.lastname: Shiratori
authors.forename: H O
authors.initials: HO
authors.lastname: Lüders
mesh_terms: D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004292:Dominance, Cerebral; D004827:Epilepsy / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D009460:Neurologic Examination / Q000379:methods; D013239:Stereotyped Behavior