title: Central nervous system infections in the rainforest zone of Nigeria.
abstract: OBJECTIVE
  To ascertain incidence rates of central nervous system infections and provide information for health care planners.
  
  
  METHODS
  A two-stage screening through supervised case referrals and diagnostic evaluation at referral centre to establish a register of CNS infections.
  
  
  METHODS
  A rural community in the rainforest zone of Nigeria with land area of 186500 m2, average daily temperature of 28 degrees C, annual rainfall of 2080 mm, adult population of 109851 and served by 26 primary, three secondary and twelve comprehensive care facilities. More than two per cent of the populations live in waterlogged areas.
  
  
  METHODS
  Adults aged sixteen years and above, constituting incident cases of CNS infections.
  
  
  METHODS
  Incident CNS infections per 100,000 populations averaged over a two year observational period.
  
  
  RESULTS
  Incidence rates were 3.6, 4.1, 2.3, 09, 1.8, 0.9 for acute bacterial meningitis, aseptic meningitis, rabies encephalitis, non-rabies encephalitis, tuberculous meningitis and chronic non-tuberculous meningoencephalitis, respectively. Syphilitic neuroarthropathy had 0.46.
  
  
  CONCLUSIONS
  Mortality from acute pyogenic meningitis and tuberculous meningitis remained distressingly high. Aseptic meningitis had the highest incidence rate, yet remained inadequately emphasised. Rabies encephalitis was the third commonest cause of CNS infection in the area.
authors.affiliation: School of Midwifery, Ollh Ihiala, Department of Medicine (Neurology/Unit), Nnamdi Azikiwe University Teaching Hospital Nnewi and Department of Surgery, University of Nigeria Teaching Hospital, Enugu, Nigeria.
authors.forename: C M
authors.initials: CM
authors.lastname: Nwosu
authors.forename: G E
authors.initials: GE
authors.lastname: Njeze
authors.forename: C
authors.initials: C
authors.lastname: Opara
authors.forename: C
authors.initials: C
authors.lastname: Nwajuaku
authors.forename: C K
authors.initials: CK
authors.lastname: Chukwurah
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002494:Central Nervous System Infections / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D003906:Developing Countries; D004569:Electroencephalography; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D020380:Needs Assessment; D009549:Nigeria / Q000453:epidemiology; D011159:Population Surveillance; D012017:Referral and Consultation; D012042:Registries; D012307:Risk Factors; D012423:Rural Health / Q000706:statistics & numerical data*; D017678:Sex Distribution; D014329:Tropical Climate; D014330:Tropical Medicine