Eudesmanolides, aromatic derivatives, and other constituents from Carpesium cernuum.
A new eudesmanolide 13-hydroxy-4 alpha H-eudesman-5,7(11)-dien-12,8 beta-olide (1) and a new aromatic derivative 3-methyl-8-acetoxy-9,10-diisobutanoyloxy-p-cymene (6), along with ten known compounds were isolated from the roots of Carpesium cernuum L. Their structures were elucidated by spectral methods (IR, EIMS, FAB-MS, 1D and 2D NMR). Compound 2, 3 and compound 10 exhibited moderate antibacterial activity against Bacillus subtilis, Escherichia coli and Staphylococcus aureus.
Yang
C
C
Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, People's Republic of China.
Zhu
Q X
QX
Zhang
Q
Q
Wang
Q
Q
Jia
Z J
ZJ
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D012717:Sesquiterpenes