[Application of total intravenous anesthesia with propofol in laparoscopic cholecystectomy: specific properties of propofol as an antioxidant].
The authors reveal the formation of free radicals in biologic objects stressing upon the influence of Propofol (Diprivan; Zeneca; London, UK) as an intravenous agent during laparoscopic cholecystectomy (LCCE) lipid peroxidation. Some LCCE surgical details help this process resulting in free radical synthesis. The antioxidant effect of Propofol in vitro constitutes a peculiar interest. This generates idea that Propofol may be used as an anesthetic or as a sedative in patients with disturbances in free radical formation.
Khinev
S
S
Tsoneva
D
D
Dafinova
K
K
Lozanov
R
R
D018686:Anesthetics, Intravenous; D000975:Antioxidants / Q000494:pharmacology; D017081:Cholecystectomy, Laparoscopic / Q000379:methods; D016166:Free Radical Scavengers / Q000008:administration & dosage; D006801:Humans; D015742:Propofol / Q000008:administration & dosage; D013050:Spectrometry, Fluorescence
D018686:Anesthetics, Intravenous; D000975:Antioxidants; D016166:Free Radical Scavengers; D015742:Propofol