title: [Severe mitral insufficiency caused by the rupture of the chordae tendinae in acromegaly. Report of a case].
abstract: Cardiovascular disease is a common finding in patients with acromegaly. In such patients, heart failure frequently leads to death. Cardiovascular manifestations of acromegaly include cardiomegaly and very often hypertension, coronary atherosclerosis, and diabetes. Primary valvular disease is less commonly observed. Because it is not clear whether acromegaly-related cardiomyopathy is a specific entity and since there are not many necropsy reports regarding mitral valve prolapse in acromegalic patients, we report the case of severe mitral regurgitation due to rupture of the chordae tendinae in a patient with mitral valve prolapse and acromegaly.
authors.affiliation: Unità Operativa di Cardiologia Ospedale degli Infermi Via Settembrini, 2 47900 Rimini.
authors.forename: S
authors.initials: S
authors.lastname: Ripa
authors.forename: L
authors.initials: L
authors.lastname: Caccamo
authors.forename: P C
authors.initials: PC
authors.lastname: Amati
authors.forename: F
authors.initials: F
authors.lastname: Bologna
authors.forename: G C
authors.initials: GC
authors.lastname: Piovaccari
mesh_terms: D000172:Acromegaly / Q000097:blood / Q000150:complications*; D013006:Growth Hormone / Q000097:blood; D006341:Heart Rupture / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000209:etiology*; D008945:Mitral Valve Prolapse / Q000150:complications*
chemical_list: D013006:Growth Hormone