title: Serum TNF-alpha level in the neoplasm patients qualified for surgical treatment.
abstract: The aim of the study was to analyze serum tumor necrosis factor alpha (TNF-alpha) levels in patients with different neoplasm types qualified for surgical treatment and to evaluate their possible correlations with circulating immune complexes (CIC), IgG, IgM, and the complement (C) compounds: C1 inhibitor (C1i), C3c and C4 levels. Studies were performed in sera from 30 neoplasm patients before surgical treatment and in 10 persons from a control group (CG) with no malignancy. Serum TNF-alpha levels were measured with the Cytogen ELISA kit. Average TNF-alpha levels measured in neoplastic patient groups qualified for surgical treatment were not significantly different from the average TNF-alpha level in the CG group.
authors.affiliation: Department of Histology and Embryology, Medical University of Lódź, Poland. gawot@bg.am.lodz.pl
authors.forename: H
authors.initials: H
authors.lastname: Gendek-Kubiak
authors.forename: J
authors.initials: J
authors.lastname: Grzegorczyk
authors.forename: E G
authors.initials: EG
authors.lastname: Gendek
authors.forename: M L
authors.initials: ML
authors.lastname: Kowalski
authors.forename: J
authors.initials: J
authors.lastname: Berner
mesh_terms: D003165:Complement System Proteins / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D009369:Neoplasms / Q000276:immunology* / Q000601:surgery; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014409:Tumor Necrosis Factor-alpha; D003165:Complement System Proteins