title: [Changes of human recombination bone morphogenetic protein-2 in bone and marrow in tail suspended rats].
abstract: OBJECTIVE
  To study human recombination bone morphogenetic protein-2 (rhBMP-2) change in bone and marrow under simulated weightlessness.
  
  
  METHODS
  5 SD rats were tail suspended for 14, 28 d with another 5 freely active rats as control. Histological samples were in situ hybridized.
  
  
  RESULTS
  rhBMP-2 expression of bone and marrow were lower in tail suspended rats than control levels (P < 0.05). rhBMP-2 expression tail suspended rats in 14 day were higher than that in 28 day suspended group (P < 0.05).
  
  
  CONCLUSIONS
  rhBMP-2 levels in rats bone and marrow were lower after tail suspension.
authors.affiliation: Department of Oral Pathology, Stomatological collage, The Fourth Military Medical University, Xi'an 710032, China.
authors.forename: C J
authors.initials: CJ
authors.lastname: Fu
authors.forename: L J
authors.initials: LJ
authors.lastname: Yang
authors.forename: X S
authors.initials: XS
authors.lastname: Cao
authors.forename: X Z
authors.initials: XZ
authors.lastname: Chen
authors.forename: L F
authors.initials: LF
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000378:metabolism*; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000235:genetics / Q000378:metabolism*; D001842:Bone and Bones / Q000378:metabolism*; D015870:Gene Expression; D019417:Hindlimb Suspension; D006801:Humans; D051381:Rats; D017207:Rats, Sprague-Dawley; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism*; D016212:Transforming Growth Factor beta; D018474:Weightlessness Simulation
chemical_list: C525718:BMP2 protein, human; C525720:Bmp2 protein, rat; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; C499469:recombinant human bone morphogenetic protein-2