Amyloid deposition in basal cell carcinoma: a cause of apparent lack of sensitivity to radiotherapy.
We describe a patient with a large nodular basal cell carcinoma (BCC), which was excised following apparent failure to respond to radiotherapy. Histological examination of the fully excised lesion demonstrated a solid mass of amyloid, which stained positively for cytokeratins, but there was no residual BCC.
Cox
N H
NH
Department of Dermatology, Cumberland Infirmary, Carlisle, UK.
Nicoll
J J
JJ
Popple
A W
AW
D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000601:surgery; D002280:Basal Cell Carcinoma / Q000150:complications* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D009666:Nose; D011836:Radiation Tolerance; D012871:Skin Diseases / Q000150:complications / Q000601:surgery; D012878:Skin Neoplasms / Q000150:complications* / Q000532:radiotherapy / Q000601:surgery; D017211:Treatment Failure