title: Isotropic beam bouquets for shaped beam linear accelerator radiosurgery.
abstract: In stereotactic radiosurgery and radiotherapy treatment planning, the steepest dose gradient is obtained by using beam arrangements with maximal beam separation. We propose a treatment plan optimization method that optimizes beam directions from the starting point of a set of isotropically convergent beams, as suggested by Webb. The optimization process then individually steers each beam to the best position, based on beam's-eye-view (BEV) critical structure overlaps with the target projection and the target's projected cross sectional area at each beam position. This final optimized beam arrangement maintains a large angular separation between adjacent beams while conformally avoiding critical structures. As shown by a radiosurgery plan, this optimization method improves the critical structure sparing properties of an unoptimized isotropic beam bouquet, while maintaining the same degree of dose conformity and dose gradient. This method provides a simple means of designing static beam radiosurgery plans with conformality indices that are within established guidelines for radiosurgery planning, and with dose gradients that approach those achieved in conventional radiosurgery planning.
authors.affiliation: Southside Cancer Center, Radiation Oncology Department, Jacksonville, FL 32207, USA.
authors.forename: T H
authors.initials: TH
authors.lastname: Wagner
authors.forename: S L
authors.initials: SL
authors.lastname: Meeks
authors.forename: F J
authors.initials: FJ
authors.lastname: Bova
authors.forename: W A
authors.initials: WA
authors.lastname: Friedman
authors.forename: J M
authors.initials: JM
authors.lastname: Buatti
authors.forename: L G
authors.initials: LG
authors.lastname: Bouchet
mesh_terms: D004307:Dose-Response Relationship, Radiation; D006801:Humans; D009010:Monte Carlo Method; D010315:Particle Accelerators / Q000295:instrumentation*; D016634:Radiosurgery / Q000295:instrumentation* / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted