Identification of Aichi virus infection by measurement of immunoglobulin responses in an enzyme-linked immunosorbent assay.
Using inhibitory enzyme-linked immunosorbent assay, seroconversions to Aichi virus were detected in 24 (42.9%) of 56 patients with gastroenteritis in six outbreaks. Virus-specific immunoglobulin M (IgM) was detected in convalescent-phase sera from 7 of 24 patients. Of the other 17 patients, 12 developed a significant increase in both IgA and IgG levels and 5 developed a significant increase in IgG alone.
Yamashita
T
T
Department of Microbiology, Aichi Prefectural Institute of Public Health, Nagare 7-6, Tsuji-machi, Kita-ku, Nagoya 462-8576, Japan. tyamashita@hi-ho.ne.jp
Ito
M
M
Tsuzuki
H
H
Sakae
K
K
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D004196:Disease Outbreaks; D004797:Enzyme-Linked Immunosorbent Assay; D005517:Foodborne Diseases; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D010125:Ostreidae / Q000821:virology; D010849:Picornaviridae / Q000145:classification* / Q000235:genetics / Q000276:immunology*; D010850:Picornaviridae Infections / Q000453:epidemiology* / Q000821:virology
D000914:Antibodies, Viral; D007136:Immunoglobulins