Synthesis and Reactions of Calix[4]arene Bisanhydrides(1).
The tetrabenzyl ether, tetra-p-bromobenzenesulfonate, and tetra-p-methylbenzenesulfonate of p-carboxymethylcalix[4]arene in the 1,3-alternate conformation have been converted to the corresponding bisanhydrides. Reactions of the bisanhydrides with alcohols or amines afford calix[4]arenes carrying two carboxymethyl and two carboalkoxymethyl or two amidomethyl groups on the upper rim positions. The substitution pattern that is established confers molecular chirality on the calixarenes.
Sharma
Shiv Kumar
SK
Department of Chemistry, Texas Christian University, Fort Worth, Texas 76129.
Gutsche
C. David
CD