Translation termination: a ghost ballet?
In the October 5th issue of Cell, clarify the end of translation on a eubacterial mRNA. By elucidating the molecular choreography of class I and class II release factors within the ribosome, they show how the steps around the release of nascent protein are ordered.
Yarus
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Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.
D004926:Escherichia coli / Q000235:genetics; D006153:Guanosine Diphosphate / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D010454:Peptide Termination Factors / Q000378:metabolism*; D014176:Protein Biosynthesis; D012343:RNA, Transfer / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism
D010454:Peptide Termination Factors; D006153:Guanosine Diphosphate; D006160:Guanosine Triphosphate; D012343:RNA, Transfer