[Neoplastic morphologic transformations and their normal analogs].
The mechanisms of possible cytoskeletal reorganizations leading to morphological transformations of cells of two types, epitheliocytes and fibroblasts, are discussed. It is suggested that the non-transformed cells of these types can exist in two morphological forms, sedentary and migratory, and that genetic changes occurring with carcinogenesis block the ability of cells to undergo transitions from the sedentary form to the migratory one.
Vasil'ev
Iu M
IuM
D002465:Cell Movement; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D006801:Humans