title: ToothPrint, a proteomic database for dental tissues.
abstract: Increasing demand exists to disseminate and integrate proteomic data as proteome analysis assumes a commanding role in the postgenome era. Databases on the World Wide Web are an effective means to share information obtained from two-dimensional gels and allied proteomic approaches. Here we report the establishment of ToothPrint, a proteomic database for dental tissues accessed at http://toothprint.otago.ac.nz. Using developing rat enamel as a prototype, ToothPrint provides a variety of functionally relevant data (ligand binding, subcellular localisation, developmental regulation) in addition to protein identification maps. Features designed to enhance usability of the website and simplify its computing requirements are also outlined. Customized for mineralizing tissues, ToothPrint should prove to be an effective bioinformatic resource for investigations of dental biology.
authors.affiliation: Department of Biochemistry, University of Otago, Dunedin, New Zealand. mike.hubbard@stonebow.otago.ac.nz
authors.forename: M J
authors.initials: MJ
authors.lastname: Hubbard
authors.forename: M J
authors.initials: MJ
authors.lastname: Faught
authors.forename: B H
authors.initials: BH
authors.lastname: Carlisle
authors.forename: P A
authors.initials: PA
authors.lastname: Stockwell
mesh_terms: D000818:Animals; D030562:Databases, Protein; D003746:Dental Enamel Proteins / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification; D015180:Electrophoresis, Gel, Two-Dimensional; D020407:Internet; D020543:Proteome; D051381:Rats; D012984:Software
chemical_list: D003746:Dental Enamel Proteins; D020543:Proteome