title: Laboratory evaluation of the Sysmex SE-9500 automated haematology analyser.
abstract: The Sysmex SE-9c500 is a new, fully automated haematology analyser, providing a complete blood count (CBC), including a five-part differential count (DC), with flagging of morphological abnormalities. The SE-9500 was evaluated according to guidelines published by the International Committee for Standardisation in Haematology (ICSH). The results demonstrated minimal carryover (< 0.01%) and excellent linearity for WBC, RBC, HGB and platelet (PLT) (r > 0.995). Samples were stable with regard to CBC parameters after storage for up to 48 h at room temperature (RT) and 4 degrees C. Imprecision was generally acceptable for all CBC parameters (CV < 5%). Correlation between the SE-9500 and reference methods was excellent (r > 0.97) for all the major CBC parameters (WBC, RBC, HGB, PLT). There was minimal interference for WBC, RBC, HGB and PLT at high concentrations of bilirubin (BIL=224 micromol/l) or triglyceride (TG=7.78 mmol/l). SE-9500 reference values for CBC parameters are presented. Our results indicate that the SE-9500 is an excellent tool for routine haematological examination.
authors.affiliation: Department of Laboratory Medicine, First University Hospital, West China University of Medical Sciences, Sichuan, China. penglim@mcwcums.com
authors.forename: L
authors.initials: L
authors.lastname: Peng
authors.forename: X
authors.initials: X
authors.lastname: Gao
authors.forename: H
authors.initials: H
authors.lastname: Jiang
authors.forename: Z
authors.initials: Z
authors.lastname: Peng
authors.forename: J
authors.initials: J
authors.lastname: Su
mesh_terms: D000328:Adult; D000368:Aged; D001772:Blood Cell Count / Q000295:instrumentation* / Q000379:methods / Q000592:standards; D001330:Electronic Data Processing; D005260:Female; D017408:Guidelines as Topic; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D006932:Hyperbilirubinemia / Q000097:blood; D006949:Hyperlipidemias / Q000097:blood; D008297:Male; D008875:Middle Aged; D012015:Reference Standards; D015203:Reproducibility of Results