title: [Application of total intravenous anesthesia with propofol in laparoscopic cholecystectomy: specific properties of propofol as an antioxidant].
abstract: The authors reveal the formation of free radicals in biologic objects stressing upon the influence of Propofol (Diprivan; Zeneca; London, UK) as an intravenous agent during laparoscopic cholecystectomy (LCCE) lipid peroxidation. Some LCCE surgical details help this process resulting in free radical synthesis. The antioxidant effect of Propofol in vitro constitutes a peculiar interest. This generates idea that Propofol may be used as an anesthetic or as a sedative in patients with disturbances in free radical formation.
authors.forename: S
authors.initials: S
authors.lastname: Khinev
authors.forename: D
authors.initials: D
authors.lastname: Tsoneva
authors.forename: K
authors.initials: K
authors.lastname: Dafinova
authors.forename: R
authors.initials: R
authors.lastname: Lozanov
mesh_terms: D018686:Anesthetics, Intravenous; D000975:Antioxidants / Q000494:pharmacology; D017081:Cholecystectomy, Laparoscopic / Q000379:methods; D016166:Free Radical Scavengers / Q000008:administration & dosage; D006801:Humans; D015742:Propofol / Q000008:administration & dosage; D013050:Spectrometry, Fluorescence
chemical_list: D018686:Anesthetics, Intravenous; D000975:Antioxidants; D016166:Free Radical Scavengers; D015742:Propofol