The level of Yop proteins secreted by Yersinia enterocolitica is changed in maltose mutants.
Enteropathogenic Yersinia enterocolitica strains express a set of plasmid-encoded proteins called Yops, involved in pathogenicity. We studied the influence of the maltose system on the production of Yop proteins and found that the level of Yop proteins of Y. enterocolitica O:9 was reduced in the presence of maltose. Transposon insertion mutants impaired with the maltose transport activity showed a decreased level in the production of Yop proteins. The transcription of the yopH gene for YopH phosphatase in these maltose mutants was unchanged and revealed a maltose mutation impaired in the secretion of Yop proteins instead of their expression.
Brzostek
K
K
Institute of Microbiology, Warsaw University, 02-096 Warsaw, Miecznikowa 1, Poland. kbrzostek@biol.uw.edu.pl
Raczkowska
A
A
D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D003470:Culture Media; D004251:DNA Transposable Elements; D015964:Gene Expression Regulation, Bacterial; D008320:Maltose / Q000235:genetics* / Q000378:metabolism*; D009154:Mutation; D017027:Protein Tyrosine Phosphatases / Q000378:metabolism; D014158:Transcription, Genetic; D015008:Yersinia enterocolitica / Q000235:genetics / Q000502:physiology*
D001425:Bacterial Outer Membrane Proteins; D003470:Culture Media; D004251:DNA Transposable Elements; D008320:Maltose; D017027:Protein Tyrosine Phosphatases; C067571:yopH protein, Yersinia