title: Prunolides A, B, and C: Novel Tetraphenolic Bis-Spiroketals from the Australian Ascidian Synoicum prunum.
abstract: Three novel tetraphenolic bis-spiroketals, prunolides A-C (1, 3, and 4) have been isolated from the Australian ascidian Synoicum prunum. The structures were determined from NMR spectroscopic data and from an X-ray analysis of prunolide A. The prunolides contain a unique 1,6,8-trioxadispiro[4.1.4.2]trideca-3,10,12-triene-2,9-dione carbon skeleton. The known compound rubrolide A (5) was also isolated.
authors.affiliation: Queensland Pharmaceutical Research Institute, Griffith University, Brisbane, Australia 4111.
authors.forename: Anthony R.
authors.initials: AR
authors.lastname: Carroll
authors.forename: Peter C.
authors.initials: PC
authors.lastname: Healy
authors.forename: Ronald J.
authors.initials: RJ
authors.lastname: Quinn
authors.forename: Carolyn J.
authors.initials: CJ
authors.lastname: Tranter