Use of Conjugated Dienones in Cyclialkylations: The Total Syntheses of (+/-)-Barbatusol, (+/-)-Pisiferin, (+/-)-Deoxofaveline, (+/-)-Xochitlolone, and (+/-)-Faveline.
Concise syntheses of five tricyclic diterpenoids are reported. The key reaction in each synthesis is a cyclialkylation of a functionalized arene with a Lewis acid-activated conjugated dienone to generate a 6,7,6-fused tricycle.
Majetich
George
G
Department of Chemistry, The University of Georgia, Athens, Georgia 30602.
Hicks
Rodgers
R
Zhang
Yong
Y
Tian
Xinrong
X
Feltman
Terry Lee
TL
Fang
Jing
J
Duncan
Sam
S