Magic Angle Spinning NMR for Reaction Monitoring and Structure Determination of Molecules Attached to Multipin Crowns.
The first example of magic angle spinning NMR on crowns has been demonstrated. The ability to monitor a reaction on a crown and to confirm the structure of the reaction product directly on the crown without resorting to chemical cleavage should greatly enhance the utility of this convenient format for combinatorial chemistry.
Chin
Jefferson
J
Preclinical Research, Sandoz Research Institute, Sandoz Pharmaceuticals Corporation Departments of Central Technologies and Combinatorial Chemistry, 59 Route 10, East Hanover, New Jersey 07936 and Chiron Mimotopes Pty Ltd, Victoria 3168, Australia.
Fell
Brad
B
Shapiro
Michael J.
MJ
Tomesch
John
J
Wareing
James R.
JR
Bray
Andrew M.
AM