title: High-resolution CT of the lungs in infants and young children.
abstract: The effects of respiratory motion and imaging at low tidal volumes can easily obscure normal anatomy as well as pathology on high-resolution computed tomography (HRCT) images of the lungs in infants and young children. The benefits of motion-free HRCT in children at full inflation and end exhalation compared with HRCT during quiet breathing has remained largely unexplored. The authors describe the application and benefits of a physiologic, noninvasive technique called controlled-ventilation to obtain high-quality HRCT images of the lungs, similar to those obtained in adults, in uncooperative young children. The availability of this method should result in greater application of HRCT as a clinical and research tool in the evaluation of childhood respiratory disease.
authors.affiliation: Columbus Children's Hospital, Ohio State University, Columbus, OH 43205, USA. flong@chi.osu.edu
authors.forename: F R
authors.initials: FR
authors.lastname: Long
mesh_terms: D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D008397:Masks; D011175:Positive-Pressure Respiration / Q000379:methods*; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed / Q000379:methods*