title: [Osteo-odonto-kerato-prosthesis. Radiographic, CT and MR features].
abstract: OBJECTIVE
  Osteo-odonto-keratoprosthesis, a complex eye surgery technique devised by Strampelli, provides a valuable opportunity to restore vision in patients with severe corneal opacification (chemical or thermal burns, bullous keratopathy, severe keratitis, consequences of perforating injuries) in whom corneal transplant or the insertion of synthetic prostheses is contraindicated because of the high risk of rejection. Successful implantation of corneal prostheses in these patients was clearly dependent on the use of perfectly biocompatible materials to support the optic. Strampelli demonstrated that thin autologous tooth sections, complete with alveolar-dental ligament fulfilled these requirements, and integrated perfectly with the eye tissues without any risk of rejection. This study aims to present the radiological aspects and postoperative outcome of 13 patients who received osteo-odonto-keratoprosthesis (bilateral in 11 cases and monolateral in 2) evaluated by plain radiography, CT and MRI.
  
  
  METHODS
  Between 1993 and 2001 we evaluated 13 patients who had undergone Strampelli's osteo-odonto-keratoprosthesis, using CT, plain radiography and MRI. All patients were examined by plain radiography; 11 patients were also examined by CT and 8 also by MRI. The time interval between surgery and the radiological evaluation ranged from 3 to 13 years with a mean follow-up of 5 years and 9 months.
  
  
  RESULTS
  All patients underwent periodic clinical and imaging examinations in the post-operative period to evaluate the osteo-dental implant and to study trophism of the transplant. No post-operative complications, either cicatricial, inflammatory or of any other nature, were clinically suspected. Only two patients showed partial reabsorption of the osteo-dental lamina - evident both on plain film and CT - 10 and 12 years after surgery. Vision was restored in all the patients, with visual acuity of 10/10 in 7 cases.
  
  
  CONCLUSIONS
  Plain radiography allows to correctly evaluate the position of the prosthesis and detect possible displacements or variations in thickness, but it fails to visualize intraocular soft tissues. Besides allowing visualization and study of the prosthesis, CT also allows optimal evaluation of the intra-orbital structures and early detection of the presence and extension of inflammatory complications that may undermine outcome of the procedure. MRI is similar to CT in its capacity to evaluate intra-orbital tissues, but has the advantage of allowing greater contrast resolution thanks to the use of different types of sequences. However, because of the long image acquisition times, this method is subject to movement artifacts that are less evident in the CT examination which, especially if performed using the spiral technique, has very short image acquisition times.
authors.affiliation: Fondazione Biomedica Europea, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Bellelli
authors.forename: A
authors.initials: A
authors.lastname: Avitto
authors.forename: M
authors.initials: M
authors.lastname: Liberali
authors.forename: F
authors.initials: F
authors.lastname: Iannetti
authors.forename: L
authors.initials: L
authors.lastname: Iannetti
authors.forename: V
authors.initials: V
authors.lastname: David
mesh_terms: D001672:Biocompatible Materials; D003315:Cornea / Q000601:surgery*; D003318:Corneal Opacity / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D019736:Prostheses and Implants / Q000009:adverse effects; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014070:Tooth; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D001672:Biocompatible Materials