Spondylolisthesis in osteogenesis imperfecta due to pedicle elongation: report of two cases.
METHODS
Two cases of spondylolisthesis due to severe elongation of pedicles in osteogenesis imperfecta are reported.


OBJECTIVE
To describe an unusual type of spondylolisthesis and its successful management.


BACKGROUND
Spondylolisthesis is known to occur in osteogenesis imperfecta. Reports in the literature are few. Pedicle elongation resulting in spondylolisthesis has only been reported once. There is no report of a successful treatment of this type of spondylolisthesis resulting from pedicle elongation.


METHODS
Two adolescent girls suffering from osteogenesis imperfecta presented with lower back pain and thoracic scoliosis. One of them had high-grade spondylolisthesis of L3-L4, L4-L5, and L5-S1, with a thoracic scoliosis. She was treated with anterior interbody fusion L3 to sacrum without instrumentation. Later, progression of her scoliosis required combined anterior and posterior instrumented fusion T1 to L1. The other girl presented with L5 spondylolisthesis and thoracic scoliosis. She has back pain as well as neurologic symptoms in her legs and is waiting for surgery.


RESULTS
At the 3-year follow-up the operated patient is symptom-free from her spine and there has been no progression of either deformity.


CONCLUSIONS
High-grade spondylolisthesis due to elongation of pedicle in osteogenesis imperfecta is uncommon. Anterior interbody fusion of all the involved motion segments has produced good pain relief and arrested deformity progression at the 3-year follow-up.
Basu
P S
PS
Whittington Hospital, London, UK. parthabasu@lineone.net
Hilali Noordeen
M H
MH
Elsebaie
H
H
D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D010013:Osteogenesis Imperfecta / Q000150:complications / Q000473:pathology* / Q000601:surgery; D012600:Scoliosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods; D013168:Spondylolisthesis / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome