[The effects of Polyrhachis vicina on immunoregulation in mice].
OBJECTIVE
To study the immuno-regulatory effects of Polyrhachis vicina Roger(PVR) in mice.


METHODS
By determining the immune function of normal mice and immune function-depressed or enhanced mice after the administration of PVR.


RESULTS
PVR (0.25 g.kg-1.d-1 x 10 d, 0.5 g.kg-1.d-1 x 10 d, 1.5 g.kg-1.d-1 x 10 d, op) had no effects on non-specific immune function (weight of immune organs) and cell immune function (delayed type hypersensitivity, DTH) in normal mice, but could improve the non-specific immune function and fluids immune function (hemolysin assay method) in immune function-depressed mice induced with hydrocortisonun (5 x 10(-2) g.kg-1.d-1 x 5 d). Both depressed DTH and enhanced DTH induced with cyclophosphamide (Cy) at the doses of 80 mg.kg-1.d-1 x 1 d and 250 g.kg-1.d-1 x 10 d ig. respectively were regulated by PVR (1.5 g.kg-1.d-1 x 10 d).


CONCLUSIONS
PVR has immuno-regulatory activities in mice.
Cai
Y
Y
No. 454 Hospital of PLA, Nanjing 210002.
Yu
G
G
D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D001000:Ants; D004342:Drug Hypersensitivity; D006968:Hypersensitivity, Delayed / Q000139:chemically induced / Q000188:drug therapy*; D007107:Immune System / Q000187:drug effects*; D007166:Immunosuppressive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008419:Materia Medica / Q000494:pharmacology* / Q000627:therapeutic use; D051379:Mice; D018345:Mice, Knockout; D010587:Phagocytosis / Q000187:drug effects*
D000276:Adjuvants, Immunologic; D007166:Immunosuppressive Agents; D008419:Materia Medica