title: Elective splenectomy in the elderly--perioperative and long-term course.
abstract: BACKGROUND
  The hazards of elective splenectomy in the elderly have not been thoroughly investigated. The aim was to assess such a well-defined cohort with respect to perioperative and long-term outcome.
  
  
  METHODS
  Fifty-two consecutively splenectomised patients during the period 1971-1995, aged 65 years or older, were followed until death (44 cases) or the end of 1999 (8 cases).
  
  
  RESULTS
  No intraoperative deaths occurred, while three patients (5.8%) died postoperatively in the 1970s. Twenty-four patients suffered from thirty-four postoperative complications, dominated by infections and haematomas. No differences were seen comparing patients with and without complications related to the American Society of Anesthesiologists' classes, total transfusion rate, steroid medication, preoperative risk diseases, "giant spleens" or the time period during which the operations were performed. In 69% of the patients, the splenectomy was beneficial. During the long-term follow-up, 25 patients suffered from 59 infectious and thromboembolic episodes and 1 surgical complication. The dominating causes of death were the primary disease (29%), myocardial infarction (20%), sepsis (12%) and cerebrovascular lesions (12%), i.e. not directly related to late effects of the operation.
  
  
  CONCLUSIONS
  High-risk patients older than 65 years with haematological disorders can safely undergo splenectomy with a low mortality rate and a reasonable rate of morbidity. The long-term course demonstrates a fair response rate, minimal surgically related complications, but thromboembolic and infectious events, and the majority of deaths unrelated to late effects of the splenectomy.
authors.affiliation: Department of Surgery, Lund University Hospital, 221 85, Lund, Sweden. birger.palsson@skane.se
authors.forename: B
authors.initials: B
authors.lastname: Pålsson
authors.forename: M
authors.initials: M
authors.lastname: Hallén
authors.forename: E
authors.initials: E
authors.lastname: Nordenström
authors.forename: R
authors.initials: R
authors.lastname: Andersson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D017558:Elective Surgical Procedures; D005260:Female; D005500:Follow-Up Studies; D006402:Hematologic Diseases / Q000601:surgery*; D006801:Humans; D008297:Male; D019990:Perioperative Care; D011183:Postoperative Complications; D013156:Splenectomy / Q000009:adverse effects / Q000401:mortality; D016896:Treatment Outcome