title: MR angiography using spin-lock flow tagging.
abstract: A method for MR angiography using an RF labeling technique is suggested. The method utilizes a slice-selective spin-lock pulse sequence for tagging the spins of inflowing blood. The pulse sequence begins with a spatially selective 90 degrees (x) RF pulse, followed by a nonselective composite locking pulse of 135 degrees (y) - n[360 degrees (y)]-135 degrees (y) and by a 90 degrees (-x) pulse. A spoiler gradient is then applied. A rapid imaging stage, which yields a T(1)rho-weighted signal from the tagged spins, completes the sequence. Untagged spins are thoroughly dephased and consequently suppressed in the image. Thus, contrast is obtained without an injection of a contrast material or image subtraction. Furthermore, the flow of the tagged bolus can be visualized. The sequence was implemented on phantoms and on human volunteers using a 1.5T scanner. The results indicate the feasibility of the suggested sequence.
authors.affiliation: Department of Biomedical Engineering, Technion IIT, Haifa, Israel. haim@biomed.technion.ac.il
authors.forename: H
authors.initials: H
authors.lastname: Azhari
authors.forename: C A
authors.initials: CA
authors.lastname: McKenzie
authors.forename: R R
authors.initials: RR
authors.lastname: Edelman
mesh_terms: D003326:Coronary Circulation; D003331:Coronary Vessels / Q000033:anatomy & histology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography / Q000379:methods*; D019047:Phantoms, Imaging