title: [Detection of the genotypic heterogeneity of Ixodes persulcatus Schulze (Acari: Ixodidae) of the North-West region of Russia and characteristics of distribution of tick-borne pathogens causing Lyme disease and Ehrlichia infections in various genotypes].
abstract: The heterogeneity of the Ixodes persulcatus population in the vicinity of Saint Petersburg was estimated by using malate dehydrogenase (MDH) isoenzyme. There are six MDH genotypes carrying 3 alleles in the Ixodes persulcatus population. The prevalence of Borrelia and Ehrlichia species in the study genotypes was analyzed. There was a difference in the prevalence and intensity of infection. The greatest abundance of Borrelia was described in the genotypes to Genogroup 1 (with allele 1). Among them, heterozygous ticks were most intensively infected. Polymerase chain reaction identified species pathogenic for man. These included 3 species of Borrelia: B. afzelii, B. garinii, and B. burgdorferi sensu stricto and 2 species of Ehrlichia muris and HGE agent. The author are the first to describe HGE agent and B. burgdorfei ss encountered in Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Semenov
authors.forename: A N
authors.initials: AN
authors.lastname: Alekseev
authors.forename: E V
authors.initials: EV
authors.lastname: Dubinina
authors.forename: U
authors.initials: U
authors.lastname: Kaufmann
authors.forename: R M
authors.initials: RM
authors.lastname: Jensen
mesh_terms: D000818:Animals; D001898:Borrelia / Q000145:classification / Q000235:genetics; D004197:Disease Reservoirs; D004536:Ehrlichia / Q000145:classification / Q000235:genetics*; D005455:Fluorescent Antibody Technique; D005838:Genotype; D006801:Humans; D007527:Isoenzymes / Q000235:genetics; D018884:Ixodes / Q000235:genetics* / Q000382:microbiology*; D008291:Malate Dehydrogenase / Q000235:genetics; D016133:Polymerase Chain Reaction; D012426:Russia
chemical_list: D007527:Isoenzymes; D008291:Malate Dehydrogenase