What is the role of stimulant laxatives in the management of childhood constipation and soiling?.
BACKGROUND
Constipation is extremely common in childhood and may lead to overflow soiling/encopresis. Standard treatment of the more severe case is to empty the bowels of impacted faeces by the use of oral or rectal laxatives and then maintain regular bowel movements by the continuation of osmotic and stimulant laxatives.


OBJECTIVE
The objective of the review was to determine the effect of stimulant laxative treatment in children with chronic constipation who may also suffer from soiling / encopresis.


METHODS
The Cochrane database of randomised controlled trials was searched. Additional citations were sought by hand searching of paediatric journals and from contact with known professionals in the field.


METHODS
All identified randomised controlled trials (RCTs) which compare the administering of stimulant laxatives to children with either placebo or alternative treatment.


METHODS
No trials were found that met the selection criteria.


RESULTS
No trials were found that adequately met the selection criteria.


CONCLUSIONS
The need exists to establish a secure footing for treatment decisions and adequately sized trials are required to provide comparative data on commonly used drugs.
Price
K J
KJ
Sheffield Children's Hospital, Western Bank, Sheffield, South Yorkshire, UK, S10 2 TH. k.j.price@sheffch-tr.trent.nhs.uk
Elliott
T M
TM
D002400:Cathartics / Q000627:therapeutic use*; D002648:Child; D003248:Constipation / Q000188:drug therapy*; D004688:Encopresis / Q000188:drug therapy*; D006801:Humans
D002400:Cathartics