Type B1 thymoma in multiple endocrine neoplasia type 1 (MEN-1) syndrome.
OBJECTIVE
Multiple endocrine neoplasia (MEN) syndromes include a group of disorders characterized by the neoplastic transformation of two or more endocrine tissues. In type 1 syndrome (MEN-1), pituitary, parathyroid and pancreatic islet tumors are most frequently represented. Thymic neoplasms are also rarely associated, and thymectomy during subtotal or total parathyroidectomy should always be considered.


METHODS
The authors describe a rare case of a 22-year-old male who presented a type B1 thymoma without myasthenia gravis associated to hyperparathyroidism, corticoadrenal adenoma and three neuroendocrine pancreatic lesions (somatostatinoma, glucagonoma and insulinoma).
De Toma
G
G
Department of Surgery Pietro Valdoni, University of Rome La Sapienza, Italy. detoma@uniroma1.it
Plocco
M
M
Nicolanti
V
V
Brozzetti
S
S
Letizia
C
C
Cavallaro
A
A
D000328:Adult; D006801:Humans; D008297:Male; D018761:Multiple Endocrine Neoplasia Type 1 / Q000473:pathology*; D011859:Radiography; D013945:Thymoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology