[Osmotic opening of the hematoencephalic barrier in experiments. Review].
This article describes the mechanism of osmotic opening of the blood-brain barrier (BBB) by intracarotic injection of a hyperosmolar agent (mannitol) and how to test the open BBB by intravital dyes, especially Evans blue.
Kozler
P
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Neurochirurgická klinika 1. LF UK a UVN, subkatedra neurochirurgie IPVZ, Praha.
D001812:Blood-Brain Barrier / Q000187:drug effects / Q000502:physiology*; D001929:Brain Edema / Q000503:physiopathology; D004396:Coloring Agents; D004234:Diuretics, Osmotic / Q000494:pharmacology; D005070:Evans Blue; D006801:Humans; D006982:Hypertonic Solutions / Q000008:administration & dosage; D066298:In Vitro Techniques; D008353:Mannitol / Q000494:pharmacology; D009995:Osmosis; D010539:Permeability
D004396:Coloring Agents; D004234:Diuretics, Osmotic; D006982:Hypertonic Solutions; D008353:Mannitol; D005070:Evans Blue