Role of gammadelta T cells in protecting normal airway function.
Since their discovery 15 years ago, the role of gammadelta T cells has remained somewhat elusive. Responses of gammadelta T cells have been found in numerous infectious and non-infectious diseases. New evidence points to gammadelta T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of gammadelta T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.
Born
W K
WK
National Jewish Medical and Research Center, Denver, Colorado 80206, USA.
Lahn
M
M
Takeda
K
K
Kanehiro
A
A
O'Brien
R L
RL
Gelfand
E W
EW
D000818:Animals; D007109:Immunity; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000378:metabolism*; D012137:Respiratory System / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000502:physiology; D013601:T-Lymphocytes / Q000502:physiology*
D016692:Receptors, Antigen, T-Cell, gamma-delta