title: Postural tachycardia syndrome in a 28-year-old Japanese woman.
abstract: Postural tachycardia syndrome is defined as the development of orthostatic symptoms without orthostatic hypotension. We report a 28-year-old female patient with postural tachycardia syndrome who exhibited palpitation, low-grade fever and weight loss. Evaluation of autonomic nervous system functions showed that cardiovagal function was normal. Sweat response to acetylcholine was decreased. Excessive blood pressure elevation was seen in phase IV of the Valsalva maneuver. Pathophysiologic factors in this case were considered to be alpha adrenergic denervation and beta adrenergic hyperresponsiveness. It is important that this syndrome be widely recognized and properly diagnosed.
authors.affiliation: First Department of Medicine, Wakayama University of Medical Science.
authors.forename: Y
authors.initials: Y
authors.lastname: Kishi
authors.forename: H
authors.initials: H
authors.lastname: Sasaki
authors.forename: T
authors.initials: T
authors.lastname: Kondo
authors.forename: K
authors.initials: K
authors.lastname: Ogawa
authors.forename: H
authors.initials: H
authors.lastname: Yamasaki
authors.forename: M
authors.initials: M
authors.lastname: Nishi
authors.forename: K
authors.initials: K
authors.lastname: Nanjo
mesh_terms: D000316:Adrenergic alpha-Agonists; D000328:Adult; D001341:Autonomic Nervous System / Q000503:physiopathology*; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D009638:Norepinephrine; D011187:Posture; D013610:Tachycardia / Q000175:diagnosis* / Q000503:physiopathology*; D018667:Tilt-Table Test; D014636:Valsalva Maneuver
chemical_list: D000316:Adrenergic alpha-Agonists; D009638:Norepinephrine