Genetic determinants of bone mineral content in premature infants.
Genetic determinants of bone mineral content in prematurely born children at 3 months and 9-11 years of age were studied. The findings suggest that multiple genes are involved in the regulation of site specific bone mass accumulation during childhood.
Backström
M C
MC
Department of Paediatrics, Vasa Central Hospital, Sandviksgatan 1-3, FIN-65110 Vasa, Finland. maria.backstrom@pp1.inet.fi
Mahonen
A
A
Ala-Houhala
M
M
Sievänen
H
H
Mäenpää
P
P
Koivisto
A M
AM
Olkku
A
A
Mäki
R
R
Mäki
M
M
D015502:Absorptiometry, Photon / Q000379:methods; D000483:Alleles; D000704:Analysis of Variance; D001835:Body Weight; D015519:Bone Density / Q000235:genetics*; D002648:Child; D004587:Electrophoresis, Agar Gel / Q000379:methods; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology*; D007334:Insulin-Like Growth Factor I / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D012150:Polymorphism, Restriction Fragment Length; D018167:Receptors, Calcitriol / Q000235:genetics; D011960:Receptors, Estrogen / Q000235:genetics
D018167:Receptors, Calcitriol; D011960:Receptors, Estrogen; D007334:Insulin-Like Growth Factor I