[Anemia and thrombocytopenia of uncertain etiology].
A 35-year-old male patient with long lasting HIV infection presented with confusion, haemolytic anaemia and thrombocytopenia. After a stable course over 7 days he suddenly developed coma and cardiogenic shock and died. Autopsy revealed thrombotic thrombocytopenic purpura with fibrin-rich deposits in the microvasculature of the brain, heart and pancreas. The pathogenesis and differential diagnosis of this fulminant disease are discussed.
Colombo
E
E
Medizinische Klinik A, Universität Basel.
Krause
M
M
Moch
H
H
D000328:Adult; D000743:Anemia, Hemolytic / Q000209:etiology* / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D015658:HIV Infections / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008168:Lung / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000473:pathology; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis* / Q000473:pathology; D012770:Shock, Cardiogenic / Q000175:diagnosis / Q000473:pathology; D013921:Thrombocytopenia / Q000209:etiology* / Q000473:pathology