A patient with Wegener's granulomatosis with initial clinical presentations of Henoch-Schönlein purpura.
The initial presentation of a patient with Wegener's granulomatosis was indistinguishable from that of Henoch-Schönlein purpura. The patient presented with skin purpura and pulmonary hemorrhage followed by purpura in the colon. The diagnosis of this patient at that time was Henoch-Schönlein purpura. With time, massive lesions in the sinus and those with cavities in the lung became apparent, and a specimen obtained from the sinus massive lesion was disclosed to be granulomatous inflammation. Retrospectively, the proteinase 3 antineutrophil cytoplasmic antibody turned out to be strongly positive in her stored serum from the time of the initial presentation.
Miyata
M
M
Fukushima Red Cross Hospital, Fukushima Medical University School of Medicine.
Kanno
K
K
Nishimaki
T
T
Sakuma
F
F
Iwatsuki
K
K
Kasukawa
R
R
D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D001324:Autoantigens / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis*; D053146:Myeloblastin; D009195:Peroxidase / Q000276:immunology; D012697:Serine Endopeptidases / Q000276:immunology; D013997:Time Factors
D019268:Antibodies, Antineutrophil Cytoplasmic; D001324:Autoantigens; D009195:Peroxidase; D012697:Serine Endopeptidases; D053146:Myeloblastin