title: Synthesis and Properties of C-Azalyxonucleosides.
abstract: 1-beta-(4-Imidazoyl)- and 1-beta-(5-uracilyl)-1,4-dideoxy-1,4-imino-L-lyxitols were synthesized stereoselectively via a sequential procedure by the addition of the corresponding metal salts of heterocycles, Swern oxidation, reductive aminocyclization, and deprotection. Their structures were determined based on X-ray crystallography. From the NMR measurements of their N-acyl derivatives, two rotational isomers were observed. Their bioassay is also described.
authors.affiliation: Department of Chemistry, Faculty of Science, Graduate School of Science and Technology, and Chemical Analysis Center, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba city 263-8522, Japan.
authors.forename: Atsuya
authors.initials: A
authors.lastname: Momotake
authors.forename: Jun
authors.initials: J
authors.lastname: Mito
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Hideo
authors.initials: H
authors.lastname: Togo
authors.forename: Masataka
authors.initials: M
authors.lastname: Yokoyama