title: Enantioselective Synthesis of (+)-Isobretonin A.
abstract: An enantioselective synthesis of (+)-isobretonin A is described. The chiral glycerol moiety was enantioselectively prepared by reduction of an optically active beta-keto sulfoxide. The all-trans trienic part of the molecule was stereoselectively synthesized via reductive elimination of a 1,6-dibenzoate 2,4-diene with sodium amalgam.
authors.affiliation: Laboratoire de Stéréochimie associé au CNRS, Ecole Européenne de Chimie, Polymères et Matériaux (ECPM), Université Louis Pasteur, 1 rue Blaise Pascal, 67008 Strasbourg, France.
authors.forename: Guy
authors.initials: G
authors.lastname: Solladié
authors.forename: Marc
authors.initials: M
authors.lastname: Adamy
authors.forename: Françoise
authors.initials: F
authors.lastname: Colobert