title: Effect of acidosis on contractile function of mesenterial lymphatic vessels in bulls.
abstract: Extracellular normocapnic acidosis inhibited spontaneous phasic contractile activity and reduced the tone of isolated bovine mesenterial lymphatic vessels. Acidosis induced dilation of lymphatic vessels due to activation of ATP-sensitive potassium channels in myocyte membrane and stimulation of NO production by endotheliocytes.
authors.affiliation: Department of Normal Physiology, I. I. Mechnikov State Medical Academy, St. Petersburg. lobov@infran.ru
authors.forename: G I
authors.initials: GI
authors.lastname: Lobov
authors.forename: N A
authors.initials: NA
authors.lastname: Kubyshkina
mesh_terms: D000138:Acidosis / Q000503:physiopathology*; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D017609:Barium Compounds / Q000494:pharmacology; D002417:Cattle; D002712:Chlorides / Q000494:pharmacology; D005905:Glyburide / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008208:Lymphatic System / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008643:Mesentery; D009119:Muscle Contraction / Q000502:physiology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*
chemical_list: D000889:Anti-Arrhythmia Agents; D017609:Barium Compounds; D002712:Chlorides; C024986:barium chloride; D005905:Glyburide