title: Activity of faropenem against resistant isolates of Streptococcus pneumoniae.
abstract: An in vitro study of the activity of 9 agents against 181 US pediatric isolates of Streptococcus pneumoniae identified imipenem and faropenem as the most active agents. Overall, faropenem was the most potent oral agent inhibiting 98% of isolates at 1 microg/mL.
authors.affiliation: Center for Research in Anti-infectives and Biotechnology, Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178, USA. jblack1@creighton.edu
authors.forename: J A
authors.initials: JA
authors.lastname: Black
authors.forename: E S
authors.initials: ES
authors.lastname: Moland
authors.forename: S A
authors.initials: SA
authors.lastname: Chartrand
authors.forename: K S
authors.initials: KS
authors.lastname: Thomson
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D007769:Lactams; D008826:Microbial Sensitivity Tests; D013296:Streptococcus pneumoniae / Q000187:drug effects*; D047090:beta-Lactams
chemical_list: D000900:Anti-Bacterial Agents; D007769:Lactams; D047090:beta-Lactams; C107057:fropenem