1H and (31)P NMR of Pentaammineruthenium(III) Complexes of Exocyclically-Coordinated Adenine and Cytosine Ligands. Evidence for Rotamers with Distinct Acidities.
1H NMR spectra of the paramagnetic complexes [L(NH(3))(5)Ru(III)], where L = derivatives of cytosine-kappa(N4) and adenine-kappa(N6), reveal rotameric isomers with distinct acid-base equilibria. (31)P NMR spectra of the 5'CMPkappa(N4) and 5'AMPkappa(N6) complexes indicate little interaction between the metal and phosphate centers. Differences between the (1)H and (31)P NMR of endo- and exocyclically-coordinated nucleosides and nucleotides are discussed and provide a means of distinguishing exocyclic from endocyclic nitrogen coordination.
Rodriguez-Bailey
V. M.
VM
Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02167.
Clarke
M. J.
MJ