title: Convenient Synthesis of N-Benzyl-1,4-dihydropyridines, Cyclohexenones, and Bicyclo[3.3.1]nonan-3-one Derivatives from 1-Aza-1,3-butadienes.
abstract: Readily available 1-aza-1,3-butadienes (enimines) react with methyl acetoacetate and acetylacetone in the presence of catalytic amounts of lithium iodide to form in high yields unsymmetrically substituted 1,4-dihydropyridines or cyclohexenones. The reaction pathway depends on the structure of the enimine used. This divergence was not observed when the enimines were reacted with dimethyl 1,3-acetonedicarboxylate to provide bicyclo[3.3.1]nonane-3-one derivatives in excellent yields in a remarkably stereoselective reaction.
authors.affiliation: Science Institute, University of Iceland, Dunhaga 3, IS-107 Reykjavik, Iceland.
authors.forename: Jon K. F.
authors.initials: JK
authors.lastname: Geirsson
authors.forename: Jonina F.
authors.initials: JF
authors.lastname: Johannesdottir