title: Quality of life in patients with urinary diversion after operation for locally advanced rectal cancer.
abstract: OBJECTIVE
  When locally advanced or recurrent rectal cancer involves the bladder or prostate, curative treatment often requires pelvic exenteration. The aim was to assess the quality of life (QoL) in disease-free patients with urinary diversion after extensive surgery for advanced rectal cancer.
  
  
  METHODS
  Twelve patients with urinary diversion (cases) were compared with 25 randomly selected patients given the same treatment, but without urinary diversion (controls). An age- and gender-adjusted general population was identified (reference). QoL was assessed with the EORTC questionnaires QLQ-C30, QLQ-CR38, and parts of the QLQ-BLM30.
  
  
  RESULTS
  The cases did not report significantly worse overall QoL than the controls or the reference population. Both cases and controls had low mean scores of sexual function, and high mean scores of male sexual problems. In the nine cases that had two stomas, overall QoL was not worse than in the control or reference groups.
  
  
  CONCLUSIONS
  Tumour-free patients did not report worse QoL scores than the controls or the general population, despite most having two stomas and low sexual function. Fear of reducing the patient's QoL should not be a major contraindication when surgery with urinary diversion is warranted to obtain curative resection.
authors.affiliation: Department of Clinical Cancer Research, The Norwegian Radium Hospital, N-0310 Oslo, Norway. m.g.guren@klinmed.uio.no
authors.forename: M G
authors.initials: MG
authors.lastname: Guren
authors.forename: J N
authors.initials: JN
authors.lastname: Wiig
authors.forename: S
authors.initials: S
authors.lastname: Dueland
authors.forename: K M
authors.initials: KM
authors.lastname: Tveit
authors.forename: S D
authors.initials: SD
authors.lastname: Fosså
authors.forename: H
authors.initials: H
authors.lastname: Waehre
authors.forename: K E
authors.initials: KE
authors.lastname: Giercksky
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003559:Cystostomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009664:Norway; D011183:Postoperative Complications; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000601:surgery*; D018709:Statistics, Nonparametric