In ovo peptide YY and epidermal growth factor administration and their effects on growth and yolk utilization in neonatal meat-type chickens (Gallus domesticus).
The effects of in ovo peptide YY (PYY) or epidermal growth factor (EGF) administration on chick growth, yolk absorption and yolk stalk function in posthatch (0-5 days) meat-type or broiler chicks were determined. At Day 18 of incubation, treated eggs were injected into the air cell with 100 microl of either PYY (Trial 1) or EGF (Trial 2) at a dosage of 600 microg/kg egg weight. Saline-treated control eggs were injected similarly with 0.9% saline. At hatch, 200 microl of (51)Cr-labeled microspheres were injected into chick yolk sacs. Epidermal growth factor increased ileal wet weight adjusted for body weight as well as ileal serosal dry matter. Body weight, feed consumption and excreta weight per bird, and relative weights of the yolk sac, intestine and liver were significantly affected by age of the chick in both trials. Relative radioactivity of the yolk sac, yolk stalk, blood, liver, and kidneys were affected by bird age in Trial 2; however, there were no significant effects due to PYY or EGF treatments on relative radioactivity of the tissues and organs examined. These data suggest that PYY and EGF had no effect on yolk absorption or yolk stalk function through 5 days in the posthatch chick.
Peebles
E D
ED
Department of Poultry Science, Mississippi State University, Mississippi State, MS 39762, USA. dpeebles@poultry.msstate.edu
Croom
J
J
Maslin
W R
WR
Whitmarsh
S K
SK
Daniel
L R
LR
Taylor
I L
IL
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002645:Chickens; D004530:Egg Yolk / Q000187:drug effects; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D007422:Intestines / Q000187:drug effects / Q000196:embryology; D008099:Liver / Q000187:drug effects / Q000196:embryology; D009929:Organ Size / Q000187:drug effects; D010063:Ovum / Q000187:drug effects*; D019894:Peptide YY / Q000494:pharmacology*; D013997:Time Factors
D019894:Peptide YY; D004815:Epidermal Growth Factor