[Digestive and transport functions of the small intestine in patients with complicated duodenal ulcer following organ-sparing operations].
A detailed study was undertaken of the functional state of cavital, membranous digestion and carbohydrate absorption in patients with duodenal ulcer before the truncal vagotomy with antrumectomy as per Billroth I (B-I TVT-AE) and Billroth II (B-II TVT-AE) and in different terms after surgery (at day 7 to 12, 6 months, 12 months, 2 to 5 years); concurrently, alpha-amylolytic activity of the small intestine content was measured together with different links of the carbohydrates digestive-transport conveyer with the aid of the carbohydrate loading tests. TVT-AE patients with complicated duodenal ulcer demonstrated a decrease in secretion of pancreatic alpha-amylase in the small intestine cavity, with the ability being secured of the pancreas to gradually normalize the post-B-I TVT-AE enzyme secretion while B-II TVT-AE failed to bring about such an effect. Different links of the carbohydrates digestive-transport conveyer tend to change in different ways. The post-B-I TVT-AE cavital digestion and absorption are noted to change to a small degree, with the membranous hydrolysis increasing by 25 to 30 percent versus the preoperative level. The post-B-II TVT-AE cavital hydrolysis comes to be significantly decreased while the membranous hydrolysis and absorption strikingly increased coming up to 50 percent of the preoperative level. The obtained findings suggest to us the importance of detection of those disorders of the small intestine absorptive function developing in the wake of the outlined operations--they are to be taken account of in choosing most adequate poly-, oligo-, and monosaccharides ratios in the carbohydrate component of the diet to be adopted in patients with postvagotomy syndromes.
Usmanov
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D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000209:etiology*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000378:metabolism; D011184:Postoperative Period; D011706:Pyloric Antrum / Q000601:surgery; D015167:Vagotomy, Truncal; D000516:alpha-Amylases / Q000378:metabolism
D000516:alpha-Amylases