title: Posterior capsule opacification with AcrySof and poly(methyl methacrylate) intraocular lenses. Comparative study with a 3-year follow-up.
abstract: OBJECTIVE
  To evaluate whether reports of reduced posterior capsule opacification (PCO) rates with AcrySof intraocular lenses (IOLs) are applicable to a mixed group of cataract patients in everyday surgical practice.
  
  
  METHODS
  Department of Ophthalmology, Kärnsjukhuset, Skövde, Sweden.
  
  
  METHODS
  A retrospective study comparing a study group receiving an AcrySof IOL (n = 145) and a group receiving a poly(methyl methacrylate) (PMMA) IOL (n = 153) was performed. The follow-up was 3 years in both groups. The performance of a neodymium:YAG laser capsulotomy was used as the end point for clinically significant PCO.
  
  
  RESULTS
  Nine capsulotomies (6.2%) were performed in the AcrySof group and 34 (22.2%) in the PMMA group. The difference in the capsulotomy rate between the 2 groups was highly significant (P <.001). The relative risk was 3.6 times higher in the PMMA group.
  
  
  CONCLUSIONS
  There was a significant difference in the frequency of capsulotomy between AcrySof and PMMA IOLs in a mixed group of cataract patients in everyday clinical practice. This finding indicates the importance of the IOL type in PCO formation.
authors.affiliation: Department of Ophthalmology Institute of Clinical Neuroscience, Sahlgrenska University Hospital/Mölndal Hospital, Mölndal, Sweden. karin.sundelin@oft.gu.se
authors.forename: K
authors.initials: K
authors.lastname: Sundelin
authors.forename: Y
authors.initials: Y
authors.lastname: Friberg-Riad
authors.forename: A
authors.initials: A
authors.lastname: Ostberg
authors.forename: J
authors.initials: J
authors.lastname: Sjöstrand
mesh_terms: D000180:Acrylic Resins / Q000009:adverse effects*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials; D002386:Cataract / Q000209:etiology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D007903:Lens Capsule, Crystalline / Q000473:pathology* / Q000601:surgery; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D019904:Polymethyl Methacrylate / Q000009:adverse effects*; D012189:Retrospective Studies
chemical_list: D000180:Acrylic Resins; D001672:Biocompatible Materials; D019904:Polymethyl Methacrylate