[Multiple bladder inverted papillomas].
OBJECTIVE
To describe the clinical and histological findings of the unusual involvement of the urinary bladder by multiple inverted papillomas of transitional cells.


RESULTS
A 53-year-old male presented with obstructive symptoms and gross hematuria lasting for one year. Ultrasound examination of the urinary bladder demonstrated two polypoid masses. Transurethral resection was performed and histopathological examination of specimens showed a subepithelial, non-atypical cell proliferation arranged in a trabecular pattern. DNA-ploidy showed diploid population and ki-67 determination revealed a low proliferation index.


CONCLUSIONS
Multiple inverted papillomas of the urinary bladder are very rare. Histological examination is essential for the definitive diagnosis. Determination of DNA-ploidy and proliferative index may be useful for appropriate management of this disease.
Márquez Moreno
A J
AJ
Servicio de Radiodiagnóstico, Servicio de Anatomía Patológica, Hospital Clínico, Málaga, España.
Julve Villalta
E
E
Alonso Dorrego
J M
JM
Rubio Garrido
F J
FJ
Blanes Berenguel
A
A
Matilla Vicente
A
A
D006801:Humans; D008297:Male; D008875:Middle Aged; D018308:Papilloma, Inverted / Q000175:diagnosis*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*