title: Synthesis of Secondary Amines via N-(Benzoyloxy)amines and Organoboranes.
abstract: A variety of primary amines (R-NH(2)) were converted to their corresponding N-(benzoyloxy)amines (i.e., R-NHOCOPh) under biphasic conditions in excellent yields (63-90%). The intermediate N-(benzoyloxy)amines were converted to their N-ethylamine derivatives upon reaction with triethylborane in THF in good yield (54-89%). These experiments demonstrated the similar chemistry of N-chloro- and N-(benzoyloxy)amines with organoboranes.
authors.affiliation: Center for Diagnostics and Drug Development, Department of Chemistry, University of Central Florida, Orlando, Florida 32816, and Department of Chemistry, University of Florida, Gainesville, Florida 32611.
authors.forename: O.
authors.initials: O
authors.lastname: Phanstiel
authors.forename: Q. X.
authors.initials: QX
authors.lastname: Wang
authors.forename: D. H.
authors.initials: DH
authors.lastname: Powell
authors.forename: M. P.
authors.initials: MP
authors.lastname: Ospina
authors.forename: B. A.
authors.initials: BA
authors.lastname: Leeson