title: Synthesis of Phosphoramides for the Lewis Base-Catalyzed Allylation and Aldol Addition Reactions.
abstract: Both chiral and achiral phosphoramides of diverse structure were prepared from diamines by the coupling to phosphorus(V) or phosphorus(III) reagents. Several enantiopure 1,2-diphenyl-1,2-ethanediamine analogues have been prepared by the reductive coupling of the corresponding N-silylimine with NbCl(4)(THF)(2) and subsequent resolution by the formation of diastereomeric menthyl carbamates. (S,S)-N,N'-Di-(1-naphthyl)-1,2-diphenyl-1,2-ethanediamine 15 was prepared by the arylation of (S,S)-1,2-diphenyl-1,2-ethanediamine with naphthyl iodide.
authors.affiliation: Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, Illinois 61801.
authors.forename: Scott E.
authors.initials: SE
authors.lastname: Denmark
authors.forename: Xiping
authors.initials: X
authors.lastname: Su
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Nishigaichi
authors.forename: Diane M.
authors.initials: DM
authors.lastname: Coe
authors.forename: Ken-Tsung
authors.initials: KT
authors.lastname: Wong
authors.forename: Stephen B. D.
authors.initials: SB
authors.lastname: Winter
authors.forename: Jun Young
authors.initials: JY
authors.lastname: Choi