Miniaturized biochemical sensing devices based on planar bilayer lipid membranes.
Methods of in-vitro artificial formation of bilayer lipid membranes (BLM) and their analytical applications are reviewed, on the basis of 122 literature references. Different techniques for preparation of free-suspended planar BLMs, and gel-, filter-, and solid-supported systems are presented. The analytical applications developed are based on direct interaction of analytes with chemically unmodified BLMs, and with systems modified by use of redox mediators, ionophores, ion-channel forming species, enzymes, antibodies, or DNA.
Trojanowicz
M
M
Department of Chemistry, Warsaw University, Poland. trojan@chem.uw.edu.pl
D015374:Biosensing Techniques / Q000295:instrumentation*; D004563:Electrochemistry; D008051:Lipid Bilayers / Q000138:chemical synthesis / Q000737:chemistry / Q000592:standards; D008832:Microchemistry / Q000295:instrumentation*; D012680:Sensitivity and Specificity
D008051:Lipid Bilayers