title: Use of the kinetic equilibrium between aminoacyl-tRNA formation and hydrolysis in inhibition assays of aminoacyl-tRNA synthetase.
authors.affiliation: DuPont Pharmaceuticals Company, Experimental Station, Route 141 & Henry Clay Road, Wilmington, Delaware 19880, USA. doug.b.jordan@dupontpharma.com
authors.forename: D B
authors.initials: DB
authors.lastname: Jordan
authors.forename: L M
authors.initials: LM
authors.lastname: Abell
authors.forename: M A
authors.initials: MA
authors.lastname: Picollelli
authors.forename: D R
authors.initials: DR
authors.lastname: Senator
authors.forename: J L
authors.initials: JL
authors.lastname: Mason
authors.forename: M J
authors.initials: MJ
authors.lastname: Rogers
authors.forename: A R
authors.initials: AR
authors.lastname: Rendina
mesh_terms: D000604:Amino Acyl-tRNA Synthetases / Q000032:analysis* / Q000037:antagonists & inhibitors / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D006868:Hydrolysis; D007700:Kinetics; D012346:RNA, Transfer, Amino Acyl / Q000378:metabolism*
chemical_list: D004791:Enzyme Inhibitors; D012346:RNA, Transfer, Amino Acyl; D000604:Amino Acyl-tRNA Synthetases