Genetic heterogeneity of Mycoplasma hominis clinical isolates detected during observation of patients with recurrent urogenital inflammation.
A rapid reproducible effective method for molecular typing of Mycoplasma hominis strains based on random amplified polymorphic DNA (RAPD) technique was developed. RAPD detected genetic heterogeneity of genomes of Mycoplasma hominis clinical isolates and showed changes in the genomes of Mycoplasma hominis clinical isolates from patients with chronic infection.
Soroka
A E
AE
Laboratory of Gene Engineering and Immunogenetics, Institute of Physico-Chemical Medicine, Ministry of Health of Russian Federation, Moscow.
Momynaliev
K T
KT
Taraskina
A M
AM
Savicheva
A M
AM
Govorun
V M
VM
D000293:Adolescent; D000328:Adult; D005260:Female; D052776:Female Urogenital Diseases / Q000382:microbiology*; D014644:Genetic Variation; D016680:Genome, Bacterial; D006801:Humans; D007249:Inflammation / Q000382:microbiology; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000382:microbiology*; D019535:Mycoplasma hominis / Q000145:classification / Q000235:genetics*; D019105:Random Amplified Polymorphic DNA Technique; D012008:Recurrence