title: Synthesis of Six-Membered Compounds by Environmentally Friendly Cyclization Using Indirect Electrolysis.
abstract: [Ni(cyclam)](ClO(4))(2)-catalyzed indirect electroreduction of olefinic bromides produced six-membered compounds in low to high yields. The synthetic intermediate 49 of Ipecac and Corynanthe alkaloids was obtained in 88% yield in a highly stereoselective manner. Lactam 66, the synthetic precursor of tacamonine, was prepared in 49% yield as a mixture of two diastereoisomers. The electrolysis of the bromoacetates gave the debrominated compounds in good yields.
authors.affiliation: Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-77, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Ihara
authors.forename: Akira
authors.initials: A
authors.lastname: Katsumata
authors.forename: Fumihito
authors.initials: F
authors.lastname: Setsu
authors.forename: Yuji
authors.initials: Y
authors.lastname: Tokunaga
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Fukumoto