Sex differences in length of survival with malignant astrocytoma, but not with glioblastoma.
In a retrospective analysis based on a malignant glioma databank, we describe effects of age, sex and diagnosis upon survival in patients with malignant cerebral glioma with a pre-treatment Karnofsky-index of 60 or more. All patients had been treated with 55-60Gy radiotherapy and nitrosurea-based adjuvant chemotherapy. We found an age-dependent sex effect upon survival in grade III astrocytoma patients, but not with glioblastoma.
Diete
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S
Department of Neurology, Otto-von-Guericke-University, Magdeburg, Germany.
Treuheit
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T
Dietzmann
K
K
Schmidt
U
U
Wallesch
C W
CW
D000328:Adult; D000367:Age Factors; D000368:Aged; D001254:Astrocytoma / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D001932:Brain Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D005260:Female; D005909:Glioblastoma / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012737:Sex Factors; D015996:Survival Rate