Use of the kinetic equilibrium between aminoacyl-tRNA formation and hydrolysis in inhibition assays of aminoacyl-tRNA synthetase.
Jordan
D B
DB
DuPont Pharmaceuticals Company, Experimental Station, Route 141 & Henry Clay Road, Wilmington, Delaware 19880, USA. doug.b.jordan@dupontpharma.com
Abell
L M
LM
Picollelli
M A
MA
Senator
D R
DR
Mason
J L
JL
Rogers
M J
MJ
Rendina
A R
AR
D000604:Amino Acyl-tRNA Synthetases / Q000032:analysis* / Q000037:antagonists & inhibitors / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D006868:Hydrolysis; D007700:Kinetics; D012346:RNA, Transfer, Amino Acyl / Q000378:metabolism*
D004791:Enzyme Inhibitors; D012346:RNA, Transfer, Amino Acyl; D000604:Amino Acyl-tRNA Synthetases