Profound T-lymphocytopenia and cryptococcemia in a human immunodeficiency virus-seronegative patient with disseminated tuberculosis.
A 47-year-old human immunodeficiency virus-seronegative West African man who presented in extremis with cachexia, lymphadenopathy, multiple organ dysfunction, and marked T-lymphocytopenia received the diagnosis of disseminated tuberculosis, cryptococcal pneumonia, and cryptococcemia. His subsequent course and our review of the literature suggest that the profound T-lymphocytopenia and ensuing cryptococcal disease were likely attributable to disseminated tuberculosis.
Zaharatos
G J
GJ
Division of Medical Microbiology, Montréal General Hospital, McGill University Health Centre, Montréal, Quebec, H3G 1A4, Canada.
Behr
M A
MA
Libman
M D
MD
D003453:Cryptococcosis / Q000209:etiology*; D018023:HIV Seronegativity; D006801:Humans; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000209:etiology*; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000150:complications*; D014397:Tuberculosis, Pulmonary / Q000150:complications*