title: [A patient with recurrent breast cancer whose liver metastasis regressed following combined use of weekly docetaxel and MPA.5'-DFUR].
abstract: A 28-year-old woman who was 10 months pregnant was diagnosed with left breast cancer. She received preoperative chemotherapy and underwent mastectomy after parturition. Endocrine therapy and adjuvant CMF and CAF was administered, but a bone metastasis appeared 2 years later and a liver metastasis 3 years later. Weekly docetaxel and MPA plus 5'-DFUR combination therapy were successively and simultaneously administered. The liver tumor regressed, and the survival time was prolonged by 1 year and 6 months. This case suggests that the combined use of both therapies was safe for the patient in serious bad condition and had a strong antitumor effect.
authors.affiliation: Dept. of Surgery, Yamanashi Prefectural Central Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Nakagomi
authors.forename: Y
authors.initials: Y
authors.lastname: Miyauchi
authors.forename: J
authors.initials: J
authors.lastname: Okuda
authors.forename: S
authors.initials: S
authors.lastname: Muto
authors.forename: H
authors.initials: H
authors.lastname: Akaike
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Mitui
authors.forename: I
authors.initials: I
authors.lastname: Ashizawa
authors.forename: S
authors.initials: S
authors.lastname: Chiba
authors.forename: M
authors.initials: M
authors.lastname: Nakazawa
authors.forename: K
authors.initials: K
authors.lastname: Imamura
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy* / Q000556:secondary*; D000077143:Docetaxel; D004334:Drug Administration Schedule; D019008:Drug Resistance, Neoplasm; D005260:Female; D005467:Floxuridine / Q000008:administration & dosage; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage / Q000031:analogs & derivatives; D043823:Taxoids
chemical_list: D043823:Taxoids; D005467:Floxuridine; D000077143:Docetaxel; D017258:Medroxyprogesterone Acetate; D017239:Paclitaxel; C025034:doxifluridine