Prunolides A, B, and C: Novel Tetraphenolic Bis-Spiroketals from the Australian Ascidian Synoicum prunum.
Three novel tetraphenolic bis-spiroketals, prunolides A-C (1, 3, and 4) have been isolated from the Australian ascidian Synoicum prunum. The structures were determined from NMR spectroscopic data and from an X-ray analysis of prunolide A. The prunolides contain a unique 1,6,8-trioxadispiro[4.1.4.2]trideca-3,10,12-triene-2,9-dione carbon skeleton. The known compound rubrolide A (5) was also isolated.
Carroll
Anthony R.
AR
Queensland Pharmaceutical Research Institute, Griffith University, Brisbane, Australia 4111.
Healy
Peter C.
PC
Quinn
Ronald J.
RJ
Tranter
Carolyn J.
CJ