title: Large strain behaviour of brain tissue in shear: some experimental data and differential constitutive model.
abstract: In this paper, some experimental measurements of the behaviour of bovine brain tissue under large shear strains in vitro are reported, and a constitutive model which is consistent with the data is developed. It was determined that brain tissue is not strain-time separable, showing slower relaxation at higher strains, and that the stresses in shear are not linear with increasing shear strain. The new constitutive model is a differential model, including both an "elastic" term, of the Mooney type and a nonlinear viscoelastic term. The latter allows for the change in relaxation behaviour with strain, by modifying an upper convected multimode Maxwell model with a damping function. The model shows good agreement with the experimental shear results and could be used to describe other types of data.
authors.affiliation: Department of Mechanical and Mechatronic Engineering, University of Sydney, Australia. bilston@mech.eng.usyd.edu.au
authors.forename: L E
authors.initials: LE
authors.lastname: Bilston
authors.forename: Z
authors.initials: Z
authors.lastname: Liu
authors.forename: N
authors.initials: N
authors.lastname: Phan-Thien
mesh_terms: D000818:Animals; D001921:Brain / Q000503:physiopathology*; D002417:Cattle; D019295:Computational Biology; D004548:Elasticity; D066298:In Vitro Techniques; D008954:Models, Biological; D012212:Rheology; D013314:Stress, Mechanical; D014783:Viscosity