Muscle heat production and anaerobic energy turnover during repeated intense dynamic exercise in humans.
1. The aim of the present study was to examine muscle heat production, oxygen uptake and anaerobic energy turnover throughout repeated intense exercise to test the hypotheses that (i) energy turnover is reduced when intense exercise is repeated and (ii) anaerobic energy production is diminished throughout repeated intense exercise. 2. Five subjects performed three 3 min intense one-legged knee-extensor exercise bouts (EX1, EX2 and EX3) at a power output of 65 +/- 5 W (mean +/- S.E.M.), separated by 6 min rest periods. Muscle, femoral arterial and venous temperatures were measured continuously during exercise for the determination of muscle heat production. In addition, thigh blood flow was measured and femoral arterial and venous blood were sampled frequently during exercise for the determination of muscle oxygen uptake. Anaerobic energy turnover was estimated as the difference between total energy turnover and aerobic energy turnover. 3. Prior to exercise, the temperature of the quadriceps muscle was passively elevated to 37.02 +/- 0.12 degrees C and it increased 0.97 +/- 0.08 degrees C during EX1, which was higher (P < 0.05) than during EX2 (0.79 +/- 0.05 degrees C) and EX3 (0.77 +/- 0.06 degrees C). In EX1 the rate of muscle heat accumulation was higher (P < 0.05) during the first 120 s compared to EX2 and EX3, whereas the rate of heat release to the blood was greater (P < 0.05) throughout EX2 and EX3 compared to EX1. The rate of heat production, determined as the sum of heat accumulation and release, was the same in EX1, EX2 and EX3, and it increased (P < 0.05) from 86 +/- 8 during the first 15 s to 157 +/- 7 J s(-1) during the last 15 s of EX1. 4. Oxygen extraction was higher during the first 60 s of EX2 and EX3 than in EX 1 and thigh oxygen uptake was elevated (P < 0.05) during the first 120 s of EX2 and throughout EX3 compared to EX1. The anaerobic energy production during the first 105 s of EX2 and 150 s of EX3 was lower (P < 0.05) than in EX1. 5. The present study demonstrates that when intense exercise is repeated muscle heat production is not changed, but muscle aerobic energy turnover is elevated and anaerobic energy production is reduced during the first minutes of exercise.
Krustrup
P
P
Copenhagen Muscle Research Centre, August Krogh Institute, University of Copenhagen, Copenhagen, Denmark.
González-Alonso
J
J
Quistorff
B
B
Bangsbo
J
J
D000328:Adult; D000693:Anaerobiosis / Q000502:physiology*; D000818:Animals; D001831:Body Temperature / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D006358:Hot Temperature; D006801:Humans; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid / Q000097:blood; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology*; D009929:Organ Size / Q000502:physiology; D010101:Oxygen Consumption / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D013848:Thigh / Q000098:blood supply
D019344:Lactic Acid