title: The Efficient, Enantioselective Synthesis of Aza Sugars from Amino Acids. 1. The Polyhydroxylated Pyrrolidines.
abstract: Beginning with (+)-serine or (-)-serine, as appropriate, convenient, high-yield, enantioselective synthesis of all eight stereoisomeric 2-hydroxymethyl-3,4-dihydroxypyrrolidines (the enantiomeric pairs of iminoribitol, -arabinitol, -xylitol, and -lyxitol) can be effected. The absolute configuration of the starting amino acid defines the set of azasugars produced.
authors.affiliation: Chemistry Department, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
authors.forename: Yifang
authors.initials: Y
authors.lastname: Huang
authors.forename: David R.
authors.initials: DR
authors.lastname: Dalton
authors.forename: Patrick J.
authors.initials: PJ
authors.lastname: Carroll