Chemoenzymatic Synthesis of Both Enantiomers of cis-6-(Hydroxymethyl)- and cis,cis-4-Hydroxy-6-(hydroxymethyl)pipecolic Acids.
Both enantiomers of cis-6-(hydroxymethyl)- and cis,cis-4-hydroxy-6-(hydroxymethyl)pipecolic acids, piperidine-based nonproteinogenic amino acids, have been synthesized from starting materials obtained from enzymatic desymmetrizations.
Chênevert
Robert
R
Département de chimie, Faculté des sciences et de génie, Université Laval, Québec (Québec), Canada G1K 7P4.
Morin
Marie-Pascale
MP