title: Specific immunoglobulins in serum of newborn lambs fed with a single dose of colostrum containing anti-peroxidase IgG.
abstract: The apparent efficiency of absorption and the decrease of specific colostral IgG after its passage into the blood stream were determined in newborn lambs fed with a single dose of colostrum containing anti-peroxidase IgG at 30 minutes, 12 hours and 24 hours after birth. When colostrum was given at 30 minutes after birth, a value of 16.9+/-4.0 per cent of anti-peroxidase IgG ingested appeared in lamb circulation. This percentage was reduced to 9.8+/-0.8 per cent when the feeding was done at 12 hours after birth and no specific IgG was detected in lambs fed at 24 hours after birth. The concentration of anti-peroxidase IgG in lambs' serum declined quickly within 96 hours of age to about 48 per cent of the initial value, and afterwards the level decreased slowly reaching a value of 10 per cent at 32 days of age. This behaviour probably reflects the protein distribution and use of absorbed antiperoxidase IgG.
authors.affiliation: Tecnología y Bioquímica de los Alimentos, Facultad de Veterinaria, Universidad de Zaragoza, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Dominguez
authors.forename: M D
authors.initials: MD
authors.lastname: Perez
authors.forename: P
authors.initials: P
authors.lastname: Puyol
authors.forename: L
authors.initials: L
authors.lastname: Sanchez
authors.forename: M
authors.initials: M
authors.lastname: Calvo
mesh_terms: D000042:Absorption; D000818:Animals; D000831:Animals, Newborn; D000918:Antibody Specificity; D000941:Antigens / Q000276:immunology; D003126:Colostrum / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D006735:Horseradish Peroxidase / Q000276:immunology*; D007074:Immunoglobulin G / Q000008:administration & dosage / Q000097:blood / Q000276:immunology*; D007408:Intestinal Absorption / Q000276:immunology; D011247:Pregnancy; D012756:Sheep / Q000276:immunology*; D013997:Time Factors
chemical_list: D000941:Antigens; D007074:Immunoglobulin G; D006735:Horseradish Peroxidase