Serum TNF-alpha level in the neoplasm patients qualified for surgical treatment.
The aim of the study was to analyze serum tumor necrosis factor alpha (TNF-alpha) levels in patients with different neoplasm types qualified for surgical treatment and to evaluate their possible correlations with circulating immune complexes (CIC), IgG, IgM, and the complement (C) compounds: C1 inhibitor (C1i), C3c and C4 levels. Studies were performed in sera from 30 neoplasm patients before surgical treatment and in 10 persons from a control group (CG) with no malignancy. Serum TNF-alpha levels were measured with the Cytogen ELISA kit. Average TNF-alpha levels measured in neoplastic patient groups qualified for surgical treatment were not significantly different from the average TNF-alpha level in the CG group.
Gendek-Kubiak
H
H
Department of Histology and Embryology, Medical University of Lódź, Poland. gawot@bg.am.lodz.pl
Grzegorczyk
J
J
Gendek
E G
EG
Kowalski
M L
ML
Berner
J
J
D003165:Complement System Proteins / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D009369:Neoplasms / Q000276:immunology* / Q000601:surgery; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014409:Tumor Necrosis Factor-alpha; D003165:Complement System Proteins