title: Effect of beta-Substituents on the Regioselectivity of the Diazomethane Ring Expansion of alpha-Methyl-alpha-methoxycyclobutanones to Cyclopentanones.
abstract: The ring expansion of 22 differently beta-substituted alpha-methyl-alpha-methoxycyclobutanones by diazomethane was studied. Migration of the less-substituted alpha-carbon was favored with the single exception of a very sterically hindered beta-benzyloxy beta-substituent.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523.
authors.forename: Lisa M.
authors.initials: LM
authors.lastname: Reeder
authors.forename: Louis S.
authors.initials: LS
authors.lastname: Hegedus