[Pelvic and spinal giant metastases from thyroid carcinomas: report of 8 cases].
OBJECTIVE
We report 8 cases of giant metastases in 7 patients with a pelvis or spinal localization in patients with differentiated carcinoma of the thyroid gland.


METHODS
Surgery was indicated for major functional disorders: pathological fracture, neurological complications. All patients were treated by embolization, tumor resection and reconstruction. All patients were given suppressive doses of thyroid hormones and 6 received complementary radiotherapy. Radioactive iodine, 100 mCu was also given in 5 cases. Outcome was analyzed retrospectively.


RESULTS
Two postoperative infections were successfully treated by surgical cleaning in one operation. There were no surgery-related neurological complications. One patient died in the immediate postoperative period due to the cancer. Mean follow-up in the other patients was 4 years. Functional outcome was excellent without local recurrence or mechanical complications.


CONCLUSIONS
These results suggest that surgical resection of giant bone metastases from thyroid carcinomas can provide favorable functional outcome similar to that achieved for small-sized metastases.
Gagey
O
O
Service d'Orthopédie, Hôpital Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre Cedex. olivier.gagey@bct.ap-hop-paris.fr
Court
C
C
Ziad
N
N
Schlumberger
M
M
D018263:Adenocarcinoma, Follicular / Q000556:secondary* / Q000601:surgery; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010384:Pelvic Bones; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000556:secondary* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000473:pathology*