Hydroxyl radical scavenging activity of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid.
Exogenous hydroxyl radical treatments increased the levels of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid (ODAP) in grass pea seedlings. Lipid peroxidation initiated by hydroxyl radicals can be alleviated when grass pea seedlings were pretreated with exogenous ODAP, suggesting that ODAP might act as an hydroxyl radical scavenger in vivo. Competing with salicylate for hydroxyl radicals in the hydroxyl radical generating/detecting system, ODAP's in vitro hydroxyl radicals scavenging activity was assessed to confirm this result, and the role of ODAP as an effective hydroxyl radical scavenger is discussed.
Gongke
Z
Z
The State Key Laboratory of Arid Agroecology, Lanzhou University, 730000, Lanzhou, PR China. gkzhou@263.net
Yingzhen
K
K
Kairong
C
C
Zhixiao
L
L
Yafu
W
W
D000599:Amino Acids, Diamino / Q000378:metabolism*; D005296:Ferrous Compounds / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000378:metabolism*; D005609:Free Radicals / Q000378:metabolism / Q000494:pharmacology; D017665:Hydroxyl Radical / Q000378:metabolism / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology; D008315:Malondialdehyde / Q000378:metabolism*; D018532:Pisum sativum / Q000187:drug effects / Q000378:metabolism*; D010944:Plants / Q000187:drug effects / Q000378:metabolism
D000599:Amino Acids, Diamino; D005296:Ferrous Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; C100126:oxalyldiaminopropionic acid; D017665:Hydroxyl Radical; D008315:Malondialdehyde