Validation of a modified GTNM classification in peri-junctional oesophago-gastric carcinoma and its use as a prognostic indicator.
OBJECTIVE
A modified GTNM classification (with additional T and N subdivisions) has been used for many years. The aim of this paper was to validate this classification in a group of patients with oesophago-gastric carcinoma and to see if the more detailed information may be useful.


METHODS
The 3-year survival of 139 consecutive patients who survived resection has been related to the individual values of the modified and international classifications.


RESULTS
A step-wise reduction in the survival was found with increasing values of G, T, N and M. The international T3 value yielded a 17.7% survival rate, when subdivided, rates of 37.5%, 17.3% and 3.2% were found. The international N1 value yielded a rate of 12.9% which subdivided into rates of 25.0%, 18.7% and 7.5%.


CONCLUSIONS
If these results are repeated in a larger and more detailed study, this modified classification may provide added information when discussing prognosis and management.
Dickson
G H
GH
Department of Gastroenterology, Worthing Hospital, West Sussex, BN11 2DH, UK. geo.m@talk21.com
Singh
K K
KK
Escofet
X
X
Kelley
K
K
D002277:Carcinoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D018572:Disease-Free Survival; D004739:England / Q000453:epidemiology; D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D016629:Esophagectomy; D004943:Esophagogastric Junction; D006801:Humans; D009367:Neoplasm Staging / Q000379:methods*; D011379:Prognosis; D015203:Reproducibility of Results; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate