title: G protein signaling and asymmetric cell division.
abstract: Asymmetric cell division depends on the polarization of the dividing cell for the correct alignment of the mitotic spindle and the localization of cytoplasmic determinants. Receptor-independent activation of heterotrimeric G proteins by the Drosophila GoLoco protein Partner of Inscuteable seems to represent a novel mechanism to control these events.
authors.affiliation: Institut für Genetik, Heinrich-Heine Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany. knust@uni-duesseldorf.de
authors.forename: E
authors.initials: E
authors.lastname: Knust
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins; D002455:Cell Division; D002462:Cell Membrane / Q000378:metabolism; D002478:Cells, Cultured; D004330:Drosophila; D029721:Drosophila Proteins; D019204:GTP-Binding Proteins / Q000378:metabolism* / Q000502:physiology*; D019476:Insect Proteins / Q000378:metabolism; D008954:Models, Biological; D010641:Phenotype; D011485:Protein Binding; D015398:Signal Transduction
chemical_list: D018797:Cell Cycle Proteins; D029721:Drosophila Proteins; D019476:Insect Proteins; C405164:Pins protein, Drosophila; D019204:GTP-Binding Proteins