[Indices of cell-mediated immunity in patients with pulmonary tuberculosis presenting with different haptoglobin phenotypes].
A comprehensive immunological evaluation was conducted together with phenotyping of haptoglobin (Hp) in 373 patients with freshly detected pulmonary tuberculosis. A marked suppression of T-cellular and antituberculous immunity has been shown to be the case in those patients presenting with Hp 2-2 phenotype of haptoglobin, which fact suggests to us a linkage between the bodily immunity status in patients with pulmonary tuberculosis and genetically determined blood marker.
Platonova
I L
IL
Sakhelashvili
M I
MI
D015415:Biomarkers / Q000097:blood*; D001782:Blood Donors; D015331:Cohort Studies; D006242:Haptoglobins / Q000032:analysis*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D010641:Phenotype; D013601:T-Lymphocytes / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000276:immunology*
D015415:Biomarkers; D006242:Haptoglobins