Mortality due to ventilator-associated pneumonia: impact of medical versus surgical ICU admittance status.
OBJECTIVE
The purpose of this study was to compare the prognosis of medical versus surgical patients developing ventilator-associated pneumonia (VAP).


METHODS
An observational cohort study included 125 consecutive patients exhibiting VAP. Incidence of death occurred at two different times: during intensive care unit (ICU) stay and during hospital stay.


RESULTS
Eighty-seven patients were included in the medical group and 38 in the surgical group. On ICU admission and at the time of VAP onset, most collected data, such as demographic parameters, severity of underlying diseases, and current illness, risk factors forVAP development andVAP characteristics were similar in the two groups. Mortality rates during ICU and hospital stays were not significantly different in medical (49%, 56%) and surgical (55%, 61%) groups. In multivariate logistic regression model adjusting for main factors of VAP mortality, surgical admittance status demonstrated no significant impact on mortality assessed during ICU stay (AOR = 1.6; 0.6 - 4.3 CI) and during hospital stay (AOR = 1.6; 0.6 - 4.2 CI).


CONCLUSIONS
In this series, after adjustment for mortality confounding factors, medical versus surgical admittance status was not a significant determinant of VAP mortality.
Leroy
O
O
Service de Réanimation Médicale et Maladies Infectieuses, Université de Lille, Centre Hospitalier, Tourcoing 59208, France.
Sanders
V
V
Girardie
P
P
Devos
P
P
Yazdanpanah
Y
Y
Georges
H
H
Beaucaire
G
G
D000368:Aged; D015331:Cohort Studies; D003422:Critical Care; D005260:Female; D005602:France / Q000453:epidemiology; D006302:Health Services Research; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D010343:Patient Admission; D018410:Pneumonia, Bacterial / Q000209:etiology / Q000382:microbiology / Q000401:mortality*; D011379:Prognosis; D012307:Risk Factors; D012122:Ventilators, Mechanical / Q000009:adverse effects*