Merkel cell carcinoma of the parotid gland associated with Warthin tumour: report of two cases.
OBJECTIVE
Two cases of Merkel cell carcinoma occurring simultaneously and in close association with a Warthin tumour of the parotid gland are reported.


RESULTS
The patients were a 65-year-old man and a 70-year-old man, respectively. The Merkel cell carcinoma component was immunoreactive for chromogranin and keratin 20 and contained neuroendocrine-type granules at the ultrastructural level.


CONCLUSIONS
The histogenesis of this heretofore undescribed combination is discussed.
Fornelli
A
A
Dipartimento di Oncologia, Sezione di Anatomia Istologia e Citologia Patologica della Università di Bologna, Bologna, Italy.
Eusebi
V
V
Pasquinelli
G
G
Quattrone
P
P
Rosai
J
J
D000235:Adenolymphoma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D000368:Aged; D015266:Carcinoma, Merkel Cell / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D002864:Chromogranins / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007381:Intermediate Filament Proteins / Q000032:analysis; D053554:Keratin-20; D008297:Male; D008854:Microscopy, Electron; D010307:Parotid Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure
D002864:Chromogranins; D007381:Intermediate Filament Proteins; C507499:KRT20 protein, human; D053554:Keratin-20