title: [MR-angiography with contrast bolus vs digital angiography in peripheral arterial occlusive disease of the legs].
abstract: OBJECTIVE
  Aim of our study was to compare MR Angiography and Digital Angiography in the diagnosis of peripheral vascular occlusive disease.
  
  
  METHODS
  Forty-five patients underwent both MRA and DSA examination of the peripheral arterial district. We employed a 1.5 Tesla MRI unit using 3D FSPGR T1-w sequence on coronal scan plane (TR=5.2 ms; TE=1.5 ms; slice=1.5/3 mm; FOV=48 cm; matrix 384x512; TA=16/24 s), before and after automatic iv injection of Gd-DTPA BMA (0.15/0.3 mmol/kg) with a flow rate of 2 ml/s. We evaluated the vascular district from renal to medio-distal tibial arteries. The acquisition of this arterial district required a semi-automatic movement of the examination table. Qualitative and quantitative analyses were carried out according to MIP reconstructions. DSA evaluation, considered as the gold standard, was performed by trans-femoral access using a 4-5F catheter.
  
  
  RESULTS
  The MRA examination detected 246 steno-occlusive lesions while 285 were identified with DSA. No statistically significant differences were found among the various degrees of stenotic lesions detected by the two METHODS. The MRA examination had specificity and sensitivity values of: 100% and 84,8% for the iliac axes; 98,9% and 94,3% for the femoral district; 100% and 84,9% for the popliteal district; 97% and 89% for tibial vessels.
  
  
  CONCLUSIONS
  MRA showed a high diagnostic accuracy close to that of DSA. On the basis of our short experience we believe that MRA will be a useful method in the detection of various degrees of peripheral artery occlusive diseases reserving DSA for the therapeutical step.
authors.affiliation: Istituto di Radiologia, Università degli Studi, L'Aquila, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Di Cesare
authors.forename: A V
authors.initials: AV
authors.lastname: Giordano
authors.forename: B
authors.initials: B
authors.lastname: Santarelli
authors.forename: G
authors.initials: G
authors.lastname: Cariello
authors.forename: L
authors.initials: L
authors.lastname: Marsili
authors.forename: A
authors.initials: A
authors.lastname: Barile
authors.forename: L
authors.initials: L
authors.lastname: Ronzino
authors.forename: C
authors.initials: C
authors.lastname: Masciocchi
mesh_terms: D000368:Aged; D000792:Angiography / Q000379:methods; D001157:Arterial Occlusive Diseases / Q000175:diagnosis*; D002908:Chronic Disease; D003287:Contrast Media; D006801:Humans; D007866:Leg / Q000098:blood supply*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008875:Middle Aged
chemical_list: D003287:Contrast Media