title: Obsessive--compulsive disorder and psychosis.
abstract: OBJECTIVE
  To study the phenomenology, treatment, course, and outcome of patients with comorbid obsessive-compulsive disorder (OCD) and psychotic features.
  
  
  METHODS
  A retrospective chart analysis was conducted on 15 patients with OCD with psychotic features. Data were collected regarding patient demographics, psychiatric diagnosis, duration of illness, treatment details, and clinically determined outcome over time.
  
  
  RESULTS
  Obsessive doubts, washing, and checking compulsions were the most commonly seen obsessive-compulsive (OC) symptoms. Of the patients, 53% had first-rank symptoms, and 77% showed significant improvement on treatment with a combination of antipsychotic and antiobsessional drugs.
  
  
  CONCLUSIONS
  The observed improvement on treatment with a combination of antiobsessional and antipsychotic drugs supports the use of combination treatment in patients who have both OC and psychotic symptoms.
authors.affiliation: Department of Psychiatry, National Institute Of Mental Health and Neurosciences, Hosur Road, Bangalore 560029, Karnataka, India.
authors.forename: V
authors.initials: V
authors.lastname: Ganesan
authors.forename: T C
authors.initials: TC
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Khanna
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001521:Behavior Therapy / Q000379:methods; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D012189:Retrospective Studies; D018967:Risperidone / Q000627:therapeutic use*
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone