Simple synthesis of climacostol, a defensive secretion by the ciliate Climacostomum virens.
Climacostol [1,3-dihydroxy-5-[(Z)-2'-nonenyl]benzene, 1], a defensive secretion by the protozoan ciliate Climacostomum virens against predators, was synthesized in a 43% overall yield in three steps by starting from methyl 1,3-bis(tert-butyldimethylsilyloxy) phenylacetate (3).
Abe
Y
Y
Department of Mathematics and Science Education, Graduate School of Science, Science University of Tokyo, Japan.
Mori
K
K
D000818:Animals; D001671:Biochemistry / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D016798:Ciliophora / Q000502:physiology*; D009682:Magnetic Resonance Spectroscopy; D012118:Resorcinols / Q000138:chemical synthesis / Q000737:chemistry*
D012118:Resorcinols; C453475:climacostol