title: Multimodality image-guided epilepsy surgery.
abstract: Co-registration of imaging modalities in the diagnosis of epilepsy is now commonly used in major epilepsy centres. However, the incorporation of these registrations into an image-guided system has only recently been developed. Using techniques of segmentation, surface matching and/or voxel-based matching, we have been able to co-register FLAIR MRI, SPECT, PET, and subdural grids into the 3-D space of the volumetric MRI and use these images on the StealthStation Image-Guided System to resect these foci. This greatly aids the surgeon in performing a more precise tailoring of the cortical resection so as to maximize the excision of the epileptogenic zone while minimizing the impact on eloquent cortex and epileptogenic foci.
authors.affiliation: Department of Neurosurgery, The Victorian Epilepsy Centre at St Vincent's Hospital, 41 Victoria Pde, Fitzroy, Victoria 3065, Australia. murphyma@svhm.org.au
authors.forename: M
authors.initials: M
authors.lastname: Murphy
authors.forename: T J
authors.initials: TJ
authors.lastname: O'Brien
authors.forename: K
authors.initials: K
authors.lastname: Morris
authors.forename: M J
authors.initials: MJ
authors.lastname: Cook
mesh_terms: D000328:Adult; D004567:Electrodes, Implanted; D004827:Epilepsy / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013238:Stereotaxic Techniques; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon