title: Enantioselective hydrolysis of potent amino acid precursors 5-oxazolidinone derivatives.
abstract: Various 5-oxazolidinones have been enantioselectively hydrolysed using PLE and HLE. It has been observed that aromatic derivatives lead to better enantiomeric excesses (up to 91%, and 78% respectively) and that PLE and HLE afford different enantiomers.
authors.affiliation: Department of Chemistry, Middle East Technical University, Ankara, Turkey. tanyeli@metu.edu.tr
authors.forename: C
authors.initials: C
authors.lastname: Tanyeli
authors.forename: B
authors.initials: B
authors.lastname: Sezen
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004950:Esterases / Q000378:metabolism; D006801:Humans; D006868:Hydrolysis; D008049:Lipase / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009904:Optical Rotation; D023303:Oxazolidinones / Q000737:chemistry*; D013237:Stereoisomerism; D013552:Swine
chemical_list: D000596:Amino Acids; D023303:Oxazolidinones; D004950:Esterases; D008049:Lipase