title: Treatment of superior limbic keratoconjunctivitis by application of autologous serum.
abstract: OBJECTIVE
  To determine the efficacy of autologous serum drops in the treatment of superior limbic keratoconjunctivitis (SLK).
  
  
  METHODS
  Twenty-two eyes of 11 patients were diagnosed with SLK. All eyes were treated with 20% diluted autologous serum eyedrops 10 times a day in addition to ongoing treatment of dry eye. Fluorescein and rose bengal staining scores, as well as subjective symptom gradings, were performed before and after 4 weeks of therapy.
  
  
  RESULTS
  Nine of the 11 patients responded well to treatment (82%). The average rose bengal and fluorescein score improved ( p < 0.05), and there was subjective improvement.
  
  
  CONCLUSIONS
  Autologous serum application can be used as an alternative mode of therapy in SLK.
authors.affiliation: Department of Ophthalmology, Tokyo Dental College, Ichikawa City, Chiba, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Goto
authors.forename: S
authors.initials: S
authors.lastname: Shimmura
authors.forename: J
authors.initials: J
authors.lastname: Shimazaki
authors.forename: K
authors.initials: K
authors.lastname: Tsubota
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D001769:Blood; D005260:Female; D019793:Fluorescein; D015590:Fluorophotometry; D006801:Humans; D007637:Keratoconjunctivitis / Q000628:therapy*; D016850:Limbus Corneae; D008875:Middle Aged; D012395:Rose Bengal; D013666:Tears / Q000378:metabolism
chemical_list: D012395:Rose Bengal; D019793:Fluorescein