title: Gastrointestinal transit of solid radiopaque markers in large and giant breed growing dogs.
abstract: Observations on food tolerance in dogs have shown that some breeds, especially the giant breeds, have a greater digestive sensitivity. One of the consequences common in these breeds is a higher faecal water content and a poor faecal quality. This could be explained, at least in part, by limited digestive capacity and function in giant breed dogs. In this report, the gastric emptying that represents one parameter of the digestive function was studied in large and giant breed dogs during their growth. Six Great Danes (GD) and six Giant Schnauzers (GS) were fed small radiopaque markers mixed with a test diet at 12, 22 and 36 weeks of age. Abdominal radiographs were made every 30 min for a period of 4 h and then hourly until 12 h. At 12 weeks of age, the gastric emptying pattern was similar in both breeds. However, from 22 weeks of age, the gastric emptying of the GD was significantly more rapid than that of GS. The gastric emptying of small markers tended to slow down in growing dogs, especially in GS. A significant positive correlation between the gastric emptying time of 50% of markers and the body weight was found. These results show that GD have a lower gastric retention time of foods, which could lead to a poor digestion and an altered absorption of nutrients. These could explained why digestive function and sensitivity could be different in dogs from different sizes and breeds.
authors.affiliation: Laboratory of nutrition and endocrinology, National Veterinary School of Nantes, BP 40706, 44307 Nantes Cedex 3, France.
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.forename: F
authors.initials: F
authors.lastname: Stambouli
authors.forename: L
authors.initials: L
authors.lastname: Martin
authors.forename: H
authors.initials: H
authors.lastname: Dumon
authors.forename: V
authors.initials: V
authors.lastname: Biourge
authors.forename: P
authors.initials: P
authors.lastname: Nguyen
mesh_terms: D000367:Age Factors; D000821:Animal Feed; D000818:Animals; D015415:Biomarkers / Q000032:analysis; D001824:Body Constitution / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D004032:Diet / Q000662:veterinary; D004285:Dogs / Q000378:metabolism / Q000502:physiology*; D005260:Female; D005746:Gastric Emptying / Q000502:physiology*; D005772:Gastrointestinal Transit / Q000502:physiology*; D007420:Intestine, Large / Q000378:metabolism / Q000502:physiology*; D007421:Intestine, Small / Q000378:metabolism / Q000502:physiology*; D011860:Radiography, Abdominal / Q000379:methods / Q000662:veterinary; D013997:Time Factors
chemical_list: D015415:Biomarkers