Small intestinal morphology in weaned piglets fed a diet containing spray-dried porcine plasma.
The hypothesis tested in this study was that the reported beneficial effects of spray-dried porcine plasma (SDPP) on piglet post-weaning performance and health are associated with a trophic effect on small intestinal mucosa. At 24 days of age, the piglets of seven sows were assigned to one of three treatment groups. One group continued to be suckled. The other two groups were weaned and offered a diet containing either 15 per cent SDPP or casein. From each treatment group, one piglet was anaesthetised and samples were taken from the small intestinal wall at 26, 28 and 31 days of age. There were no significant effects of SDPP versus casein on villus length. On average, there was less mitotic activity in the SDPP -fed piglets than in those fed casein on days 4 and 7 after weaning. As less mitotic activity leads to less immature enterocytes, this may provide a mechanism for the reported beneficial effects of SDPP on performance and health.
van Dijk
A J
AJ
Co-operative Central Laboratory CCL-Nutricontrol of Cehave Landbouwbelang, 5460 AC Veghel, The Netherlands. Albert.van.dijk@CCL-Nutricontrol.nl
Niewold
T A
TA
Margry
R J
RJ
van den Hoven
S G
SG
Nabuurs
M J
MJ
Stockhofe-Zurwieden
N
N
Beynen
A C
AC
D000821:Animal Feed; D000818:Animals; D001798:Blood Proteins / Q000008:administration & dosage* / Q000378:metabolism; D001835:Body Weight; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000378:metabolism; D005260:Female; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism; D007421:Intestine, Small / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D011897:Random Allocation; D013552:Swine / Q000033:anatomy & histology / Q000378:metabolism*
D001798:Blood Proteins; D004044:Dietary Proteins