title: Seroprevalence of Helicobacter pylori among the diabetic population in Bangladesh: a comparative serological study on the newly diagnosed and older diabetics.
abstract: This prospective study was designed to find out the prevalence of H. pylori infection among the diabetic population in Bangladesh with a comparison between the newly diagnosed and older diabetics. For this study 520 diabetic patients: 152 (29%) newly diagnosed and 368 (71%) older diabetics of both sexes (250 male, 270 female) with a mean age of 58.5 +/- 12.04 years (range 10-70 years), were selected randomly from out and in-patient departments of BIRDEM, Dhaka. Mean fasting and 2 hours post load blood glucose level of the studied population was 10.53 +/- 4.08 mmol/L and 18.35 +/- 9.44 mmol/L respectively. The mean duration of the newly diagnosed diabetics was 0.44 +/- 0.35 years (range 2 days-1 year) and 6.78 +/- 5.45 (range 1-30) years for the older diabetics. H. pylori infection was defined as a true positive ELISA test result of > 1.5 standard deviation above the cut-off values of 15 AU/ml for adults and 10 AU/ml for children for anti H. pylori IgG. Of the studied population 441 (84.8%)--132 newly diagnosed and 309 (83.96%) older diabetics were seropositive for H. pylori infection. No significant differences were observed between the newly diagnosed and older diabetics (86.84% Vs 83.96%; p > 0.05).
authors.affiliation: Deptt. of Gastrointestinal, Liver and Pancreatic Diseases, BSMMU, Dhaka.
authors.forename: M A
authors.initials: MA
authors.lastname: Miah
authors.forename: M T
authors.initials: MT
authors.lastname: Rahman
authors.forename: M
authors.initials: M
authors.lastname: Hasan
authors.forename: A K
authors.initials: AK
authors.lastname: Khan
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D001459:Bangladesh / Q000453:epidemiology; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis; D004415:Dyspepsia / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D017678:Sex Distribution; D012959:Socioeconomic Factors; D013997:Time Factors
chemical_list: D001786:Blood Glucose