title: Preparation of delta-Chloro-alpha-allenyl Ketones by Acylation of 3-Buten-1-ynes.
abstract: AlCl(3)-mediated acylation of 3-buten-1-yne derivatives with acyl chlorides yields a mixture of 5-chloro-2,3-pentadienones and 3-chloro-2,4-pentadienones. The proportion of allenyl ketones vs conjugated dienic ketones depends on the substitution pattern of the starting enyne. Acylation of 5-acetoxy-3-buten-1-ynes leads to the corresponding allenyl ketones (6-acetoxy-5-chloro-2,3-pentadienones).
authors.affiliation: Laboratoire de Synthèse Organique, URA au CNRS no. 1411, Centre. de St-Jérôme, Av. Esc. Normandie-Niemen, 13397 Marseille Cedex 20, France.
authors.forename: Christiane
authors.initials: C
authors.lastname: Santelli-Rouvier
authors.forename: Sophie
authors.initials: S
authors.lastname: Lefrère
authors.forename: Maurice
authors.initials: M
authors.lastname: Santelli