title: A novel method of synthesis of 2,4-diamino-6-arylmethylquinazolines using palladium(0)-catalyzed organozinc chemistry.
authors.affiliation: Dana-Farber Cancer Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA. andre_rosowsky@dfci.harvard.edu
authors.forename: A
authors.initials: A
authors.lastname: Rosowsky
authors.forename: H
authors.initials: H
authors.lastname: Chen
mesh_terms: D002384:Catalysis; D004791:Enzyme Inhibitors / Q000737:chemistry; D005493:Folic Acid Antagonists / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D011743:Pyrimidines / Q000737:chemistry; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D015032:Zinc / Q000737:chemistry
chemical_list: D004791:Enzyme Inhibitors; D005493:Folic Acid Antagonists; D011743:Pyrimidines; D011799:Quinazolines; C013474:2,4-diaminoquinazoline; D010165:Palladium; D015032:Zinc; C024530:piritrexim