[Hereditary cancer: identification, genetic heterogeneity, medico-genetic consult].
The paper deals with a role of inherited factors responsible for the occurrence of malignant tumors. Inherited types of cancer are shown to occur virtually at its sites and averaged 5-15%. Formalized criteria for identifying inherited cancer diseases and their etiological and genetic heterogeneity are presented. A role of genes that genetically predispose to particular forms of cancer is shown, which allows for early (preclinical) diagnosis and prevention of cancer diseases.
Gar'kavtseva
R F
RF
Kazubskaia
T P
TP
Liubchenko
L N
LN
Kozlova
S I
SI
Belev
N F
NF
Sel'chuk
V Iu
VIu
D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease; D006801:Humans; D009369:Neoplasms / Q000235:genetics*