title: CD4(+) regulatory T cells.
abstract: There is now compelling evidence that CD4(+) T cells that specialize in the suppression of immune responses play a key role in the control of immune pathology. Recently, there have been a number of reports that have provided information on the generation of CD4(+) regulatory T cells in the thymus and in the periphery. These cells have also been identified in humans, paving the way for analysis of the function of CD4(+) regulatory T cells in immune-mediated disease.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford, South Parks Road, OX1 3RE, Oxford, UK. simon.read@path.ox.ac.uk
authors.forename: S
authors.initials: S
authors.lastname: Read
authors.forename: F
authors.initials: F
authors.lastname: Powrie
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D016207:Cytokines / Q000502:physiology; D006801:Humans; D008213:Lymphocyte Activation; D051379:Mice; D015375:Receptors, Interleukin-2 / Q000032:analysis; D016176:T-Lymphocyte Subsets / Q000145:classification; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology
chemical_list: D016207:Cytokines; D015375:Receptors, Interleukin-2