title: Effect of defects on thermal denaturation of DNA oligomers.
abstract: Effect of defects on the melting profile of short heterogeneous DNA chains is calculated using the Peyrard-Bishop Hamiltonian. On-site potential on a defect site is represented by a potential that has only a short-range repulsion and a flat part without well of the Morse potential. Stacking energy between two neigbouring pairs involving a defect site is also modified. The results are found to be in good agreement with the experiments.
authors.affiliation: Department of Physics, Banaras Hindu University, Varanasi 221 005, India.
authors.forename: N
authors.initials: N
authors.lastname: Singh
authors.forename: Y
authors.initials: Y
authors.lastname: Singh
mesh_terms: D004247:DNA / Q000648:ultrastructure*; D006358:Hot Temperature; D006860:Hydrogen Bonding; D015233:Models, Statistical; D008962:Models, Theoretical; D009690:Nucleic Acid Conformation; D013696:Temperature; D013816:Thermodynamics
chemical_list: D004247:DNA