title: Acute versus chronic sodium bicarbonate ingestion and anaerobic work and power output.
abstract: BACKGROUND
  The aim of this study was to compare and contrast the effects of acute versus chronic sodium bicarbonate ingestion.
  
  
  METHODS
  
  
  
  METHODS
  Eight male, (mean+/-SE): age, 20.8+/-0.4 yrs; height, 179.6+/-0.6 cm; body mass, 79.4+/-0.85 kg, Sigma7skf, 48.6+/-4.8 mm, VO2max=55.9+/-0.8 ml x kg(-1) x min(-1)) volunteer subjects, ingested NaHCO3 in either a dose of 0.5 g x kg(-1) body mass acutely or the same dose daily over a period of six days in order to determine whether there were any differences in performance of 90 sec maximal cycling ergometry.
  
  
  METHODS
  After subjects undertook an initial control (C) test session, all were then randomly assigned to one of two groups, acute or chronic NaHCO3 ingestion. Subjects in the acute ingestion (AI) group completed their supplemented test on day one, and then on the following day. Chronic ingestion (CI) subjects completed the test after one day of chronic ingestion as well as following six days of bicarbonate ingestion. Following ten days rest, subjects repeated the protocol in the opposite group.
  
  
  METHODS
  Blood samples were taken pre- and postingestion, daily, and pre- and postexercise and were analysed for, pH, Base excess (BE), HCO3-, PO2, PCO2, Na+, K+, Cl-, and lactate.
  
  
  RESULTS
  Both the chronic (CI) and acute ingestion (AI) groups were significantly different to the control (C) value (p<0.001 and p<0.05, respectively).
  
  
  CONCLUSIONS
  We would suggest using chronic ingestion as a means to improve high intensity work rather than the acute ingestion of sodium bicarbonate. The ingestion of sodium bicarbonate, over a period of six days, significantly improved work output two days after bicarbonate ingestion ceased.
authors.affiliation: Department of Sport and Exercise Science, University of Bath, Bath, England, UK. l.mcnaughton@bath.ac.uk
authors.forename: L
authors.initials: L
authors.lastname: Mc Naughton
authors.forename: D
authors.initials: D
authors.lastname: Thompson
mesh_terms: D000136:Acid-Base Equilibrium; D000328:Adult; D015308:Anaerobic Threshold; D000704:Analysis of Variance; D004573:Electrolytes; D015444:Exercise / Q000502:physiology*; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008297:Male; D017693:Sodium Bicarbonate / Q000097:blood / Q000494:pharmacology*
chemical_list: D004573:Electrolytes; D019344:Lactic Acid; D017693:Sodium Bicarbonate