[Prenatal corticoid therapy in hypertensive syndromes of pregnancies and its effects in maternal blood pressure].
OBJECTIVE
To evaluate the behaviour of blood pressure among hypertensive pregnants during glucocorticoid therapy (LIGGINS scheme) in order to accelerate the maturity of fetal lung.


METHODS
In a retrospective study, 27 pregnant with a story of hypertensive disorder, between 24 and 34 weeks, during glucocorticoid cycle were avaluated. For this matter, statistical analisis were performed using the means of systolic (SBP) and diastolic blood pressure during the therapy days, on the day before and on the day after. The results were statistically analyzed with F statistic test ( significant if p<005)


RESULTS
There was no statistical variance in blood pressure levels, neither in SBP nor in DBP. There was no difficulty in clinical controls and no change in antihypertensive drugs related to glucocorticoid therapy.


CONCLUSIONS
Our results show observe the safety of glucocorticoid therapy among pregnant women with hypertensive disorders related to the possible raising of the blood pressure levels.
Sass
N
N
Hospital e Maternidade Escola Doutor Mário de Moraes Altenfelder Silva, São Paulo, SP. nelsonsa.alp@zaz.com.br
Cançado
R R
RR
Oliveira
M L
ML
Torloni
M R
MR
D000305:Adrenal Cortex Hormones / Q000494:pharmacology* / Q000627:therapeutic use; D001623:Betamethasone / Q000494:pharmacology / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects*; D003907:Dexamethasone / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D005325:Fetal Organ Maturity / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008168:Lung / Q000196:embryology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology*; D011295:Prenatal Care; D012189:Retrospective Studies; D013577:Syndrome
D000305:Adrenal Cortex Hormones; D003907:Dexamethasone; D001623:Betamethasone