Cerebral cryptococcal granuloma in a cat.
A 7-year-old cat was presented for seizures. Cerebrospinal fluid cytology and serology were consistent with a diagnosis of toxoplasmosis. The cat was treated with clindamycin but seizures continued and additional neurological signs developed over 6 months. A mass lesion was identified in the left cerebral hemisphere using magnetic resonance imaging (MRI). The lesion enhanced after gadolidium and a tumour was considered likely. Histologically, the lesion proved to be a cryptococcal granuloma and retrospective serology confirmed that the cat had cryptococcosis at its initial presentation. This report provides the first description in the veterinary literature of the MRI appearance of a cerebral cryptococcoma and emphasises the importance of performing cryptococcal antigen determination in cats with signs of intracranial disease.
Foster
S F
SF
Department of Veterinary Clinical Sciences, The University of Sydney, NSW, Australia.
Charles
J A
JA
Parker
G
G
Krockenberger
M
M
Churcher
R M
RM
Malik
R
R
D000818:Animals; D002371:Cat Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000473:pathology; D002415:Cats; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000175:diagnosis / Q000662:veterinary*; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D016919:Meningitis, Cryptococcal / Q000175:diagnosis / Q000662:veterinary*