title: Pharmacological actions and therapeutic uses of cannabis and cannabinoids.
abstract: This review highlights the pharmacology, pharmacokinetics, pharmacological actions, therapeutic uses and adverse effects of cannabinoids. The effect of cannabinoids on anaesthesia is mentioned briefly. Important advances have taken place in cannabinoid research over the last few years and have led to the discovery of novel ligands. The possible clinical applications of these ligands and the direction of future research are discussed.
authors.affiliation: Anaesthesia & Pain Management, Department of Anaesthesia, Grampian University Hospitals, Aberdeen AB25 2ZN, UK.
authors.forename: R N
authors.initials: RN
authors.lastname: Kumar
authors.forename: W A
authors.initials: WA
authors.lastname: Chambers
authors.forename: R G
authors.initials: RG
authors.lastname: Pertwee
mesh_terms: D000758:Anesthesia; D002186:Cannabinoids / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D002188:Cannabis / Q000009:adverse effects; D004347:Drug Interactions; D006801:Humans; D009128:Muscle Spasticity / Q000188:drug therapy; D010146:Pain / Q000188:drug therapy; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D002186:Cannabinoids; D010936:Plant Extracts