title: Cancer of esophagus: ten years experience at CENAR, Quetta.
abstract: BACKGROUND
  A retrospective study of 659 patients of Ca Esophagus was conducted from 1st January 1990 to 31st December 1999 (10 years) at CENAR Quetta. The aim of this study was to highlight the incidence, early detection, management, and various other parameters of Ca Esophagus.
  
  
  RESULTS
  During this period, 5819 new cases of cancer were registered. Cases of Ca Esophagus constituted 659 (11.32%) in number. It was studied that this cancer was the 3rd most common cancer registered in both sexes at our centre. 65 new cases of Ca Esophagus were registered at CENAR Quetta per annum on an average. Males slightly dominated the females. Maximum number of cases 470 (71.31%), were reported between ages 41-60 years with a median age of 55 years. Maximum number of cases 399 (60.57%), involved lower 3rd of Esophagus. Squamous cell carcinoma was the most common histopathology seen in 574 cases (87.10%). These patients were mainly treated with radiation therapy, palliatively, because by the time they reported, they were found in stage III and beyond. Some patients were also treated with chemotherapy along with radiation, but the overall prognosis was poor. A few patients have also undergone palliative surgery, such as pull through or push through tubes prior to radiotherapy.
  
  
  CONCLUSIONS
  Since the patients presented with late & advanced disease, it is, therefore, recommended that all cases of dysphagia particularly from this region of the country should be thoroughly investigated with the suspicion of Ca Esophagus. It is further suggested that general population be educated about the potential risk factors like smoking, use of naswar, beetle nut chewing, and intake of very hot food & beverages.
authors.affiliation: Centre for Nuclear Medicine and Radiotherapy (CENAR), Quetta.
authors.lastname: Roohullah
authors.forename: A K
authors.initials: AK
authors.lastname: Khursheed
authors.forename: G M
authors.initials: GM
authors.lastname: Burdey
authors.forename: S R
authors.initials: SR
authors.lastname: Hamdani
authors.forename: I
authors.initials: I
authors.lastname: Javaid
authors.forename: S
authors.initials: S
authors.lastname: Kamran
authors.forename: J
authors.initials: J
authors.lastname: Nusrat
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D002294:Carcinoma, Squamous Cell; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors