Vasculitic neuropathies.
Vasculitis typically affects the 50- to 400-micron vessels of the vasa nervorum, leading to randomly distributed ischemia along the course of the nerve. This, in turn, leads to a distinctive picture, multiple mononeuropathy, as a frequent but not invariant clinical consequence of vasculitis. The diagnosis of vasculitic neuropathy is usually made by biopsy histologic confirmation. The response to treatment varies among different vasculitides; vasculitis restricted to the peripheral nervous system is often especially responsive.
Griffin
J W
JW
Department of Neurology, Hopkins University School of Medicine, Baltimore, Maryland, USA. jgriffi@jhmi.edu
D006801:Humans; D009336:Necrosis; D010523:Peripheral Nervous System Diseases / Q000150:complications / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy