Transient renal tubulopathy in a Labrador retriever.
A four-month-old male Labrador retriever was presented for polyuria, polydipsia and persistent euglycaemic glucosuria. On referral, diagnostic tests demonstrated abnormal fractional excretions of electrolytes, increased urinary excretion of selected amino acids, mild renal tubular acidosis and mild proteinuria, indicating renal tubular dysfunction. Pyelonephritis was suspected and potentiated amoxycillin was administered. On re-evaluation at six months of age, the dog was no longer polyuric or polydipsic and the metabolic abnormalities associated with the tubulopathy had resolved. Transient Fanconi's syndrome has not previously been reported in small animals. This report demonstrates the potential for recovery of function in cases presenting with renal tubulopathies.
Jamieson
P M
PM
Department of Veterinary Clinical Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian.
Chandler
M L
ML
D000658:Amoxicillin / Q000627:therapeutic use; D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004327:Drinking Behavior; D005198:Fanconi Syndrome / Q000473:pathology / Q000662:veterinary*; D008297:Male; D010406:Penicillins / Q000627:therapeutic use; D011141:Polyuria / Q000209:etiology / Q000662:veterinary
D010406:Penicillins; D000658:Amoxicillin