title: [C1-esterase inhibitor in ACE inhibitor-induced severe angioedema of the tongue].
abstract: Angio-oedema are often massive but temporary swellings of the soft tissue of the face or the throat, which can also affect other regions of the human body (e.g. the skin or internal organs). An oedema of the face and throat represents a life-threatening situation. Apart from the clinical condition of the patient and detailed knowledge of the medical history (incl. medical applications), the treatment should depend on the different pathogenesis. In this reported case, we describe the severe clinical development of an angio-oedema under a long-term treatment with an ACE-inhibitor, which in the end was only successfully treated with the application of a C1 inhibitor concentrate.
authors.affiliation: Klinik für Anaesthesie und Intensivmedizin, Klinikum Südstadt Rostock.
authors.forename: O
authors.initials: O
authors.lastname: Steinbach
authors.forename: R
authors.initials: R
authors.lastname: Schweder
authors.forename: B
authors.initials: B
authors.lastname: Freitag
mesh_terms: D000402:Airway Obstruction / Q000139:chemically induced / Q000188:drug therapy; D000799:Angioedema / Q000139:chemically induced* / Q000188:drug therapy / Q000235:genetics; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D003174:Complement C1 Inactivator Proteins / Q000627:therapeutic use*; D003422:Critical Care; D004359:Drug Therapy, Combination; D004656:Enalapril / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008875:Middle Aged; D012307:Risk Factors; D014060:Tongue Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000235:genetics
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D003174:Complement C1 Inactivator Proteins; D004656:Enalapril