Bowel perforation due to gastrointestinal autonomic nerve tumour associated with neurofibromatosis type 1.
Gastrointestinal autonomic nerve (GAN) tumours form a distinct subcategory of gastrointestinal stromal tumours, and are thought to originate from the enteric autonomic plexus. To date, a total of 45 cases have been documented in the literature; a few of these cases were associated with neurofibromatosis type 1 (NF-1). Bowel perforation due to other gastrointestinal stromal tumours has been reported only twice, but never in association with a GAN tumour. We describe a 40-year-old woman with NF-1 who had bowel perforation due to a GAN tumour. The patient underwent radical surgical resection and remained tumour free for at least 4 years, which may indicate a good prognosis.
Odeh
M
M
Department of Internal Medicine B, Bnai Zion Medical Centre and Technion Faculty of Medicine, Israel Institute of Technology, Haifa, Israel.
Misselevich
I
I
Oliven
A
A
D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000601:surgery; D010524:Peripheral Nervous System Neoplasms / Q000150:complications* / Q000601:surgery; D011379:Prognosis