[Relationship between EGG and the dynamic process of motion sickness induced by optokinetic vection].
OBJECTIVE
To investigate the correlation between Electrogastrography (EGG) and the occurrence of nausea or/and vomit as well as the development of motion sickness (MS) induced by optokinetic stimulation (OPS) and to provide a clue and method for prediction and prevention of MS.


METHODS
Twenty male subjects, aged from 18 to 25 years, performed the test only once with the optokinetic drum rotated around a vertical axis at the speed of 60 degrees/s for 15 min. Nausea and EGG signals were observed and recorded.


RESULTS
(1)Both the increment of tachygastric percentage and the decrement of primary wave percentage of EGG in eleven subjects with nausea were significantly larger than those in nine subjects with no nausea (both P < 0.001). (2)The circular vection preceded the changes of EGG in eleven subjects with nausea while the MS scores in eleven subjects with nausea were higher than those in nine subjects with no nausea (P < 0.001). (3)During the rotation of drum, the decrement of primary wave percentage or the increment of tachygastria percentage also preceded the occurrence of nausea in eleven subjects with nausea (both P < 0.01).


CONCLUSIONS
(l)The changes of EGG in subjects with nausea were significantly greater than those of EGG in subjects with no nausea. (2)There was a close relationship between circular vection or illusory self-rotation and EGG changes as well as the occurring of nausea induced by OPS. (3)Changes of EGG preceded the nausea of MS induced by OPS.
Zhang
H
H
Institute of Space Medico-Engineering, Beijing, China.
Yang
F
F
Liu
Z Q
ZQ
Zhang
F S
FS
Peng
Y K
YK
Yang
T D
TD
D000293:Adolescent; D000328:Adult; D004594:Electrophysiology; D006801:Humans; D008297:Male; D009041:Motion Sickness / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D009325:Nausea / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D009903:Optical Illusions; D010775:Photic Stimulation; D012399:Rotation / Q000009:adverse effects*; D013270:Stomach / Q000502:physiology*; D014839:Vomiting / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control