The potential for adverse drug reactions in elderly patients.
This study examined inappropriately prescribed drugs, inappropriate dosages of drugs, inappropriate combinations of drugs, and numbers of drugs and their potential for causing adverse drug reactions (ADRs) in the elderly. The study also looked at whether the number of diagnoses made a difference in the drugs' potential to cause ADRs. A retrospective audit was made of 146 patients diagnosed with congestive heart failure (CHF) who were admitted to a suburban community agency. Significant correlations were found between the number of medications prescribed and the number of inappropriate medications, the number of medications prescribed and the number of inappropriate dosages of medications, and the number of medications prescribed and the number of potential drug interactions. Multiple diagnoses did not make a difference.
Gallagher
L P
LP
Pace University, Lienhard School of Nursing, Pleasantville, NY 10709, USA. lgallagher@fsmail.pace.edu
D000368:Aged; D000369:Aged, 80 and over; D002317:Cardiovascular Agents / Q000009:adverse effects* / Q000494:pharmacology; D015897:Comorbidity; D004347:Drug Interactions; D005260:Female; D006299:Health Services for the Aged / Q000592:standards*; D006333:Heart Failure / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008485:Medical Audit; D009518:New York / Q000453:epidemiology; D019338:Polypharmacy
D002317:Cardiovascular Agents