[Granulomatous slack skin: partial remission following intralesional administration of interferon-alpha and PUVA].
Granulomatous slack skin (GSS) is a rare cutaneous T-cell lymphoma which typically runs a protracted and indolent course. On histopathological assessment lymphoid infiltrates with multinucleated giant cells in the dermis and subcutis with elastophagocytosis can be observed. Skin lesions are characterized by pendulous folds. We report on the successful response of the lesions to intralesional interferon alpha combined with PUVA.
Schmook
T
T
Dermatologische Klinik, Universitätsspital Zürich, Gloriastrasse 31, CH-8091 Zürich.
Hofbauer
G
G
Kempf
W
W
Burg
G
G
Dummer
R
R
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D016898:Interferon-alpha / Q000008:administration & dosage*; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D011701:PUVA Therapy; D012074:Remission Induction; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors
D000970:Antineoplastic Agents; D016898:Interferon-alpha