title: Adverse events of premixed nitrous oxide and oxygen for procedural sedation in children.
abstract: In France, administration of premixed 50% nitrous oxide and oxygen for procedural sedation is under close supervision by the French Drug Agency before final approval for use. We have examined the frequency of adverse events in children sedated with 50% nitrous oxide and oxygen over a broad range of non-specialised facilities. A mean of 0.33% (SD 0.10) children had major adverse events. Thus, premixed 50% nitrous oxide and oxygen seems to be a safe option for procedural sedation in children.
authors.forename: O
authors.initials: O
authors.lastname: Gall
authors.forename: D
authors.initials: D
authors.lastname: Annequin
authors.forename: G
authors.initials: G
authors.lastname: Benoit
authors.forename: E
authors.initials: E
authors.lastname: Glabeke
authors.forename: F
authors.initials: F
authors.lastname: Vrancea
authors.forename: I
authors.initials: I
authors.lastname: Murat
mesh_terms: D000293:Adolescent; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D016292:Procedural Sedation; D000075202:Contraindications; D004338:Drug Combinations; D005602:France; D006801:Humans; D007223:Infant; D009609:Nitrous Oxide / Q000009:adverse effects*; D010100:Oxygen; D011446:Prospective Studies
chemical_list: D018685:Anesthetics, Inhalation; D004338:Drug Combinations; D009609:Nitrous Oxide; D010100:Oxygen