Two signals are better than one: border cell migration in Drosophila.
Recent studies of border cell migration during Drosophila oogenesis demonstrate that the EGFR and PDGFR signaling pathways act in a partially redundant manner to guide this process. Evidence presented shows that PDGFR signaling directs border cell migration via Rac and the Rac activator Mbc/CED-5/Dock180.
Gupta
T
T
HHMI/Department of Molecular Biology, Princeton University, New Jersey 08544, USA.
Schüpbach
T
T
D000818:Animals; D002465:Cell Movement / Q000502:physiology*; D004330:Drosophila / Q000196:embryology*; D005260:Female; D009866:Oogenesis / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*