Successful transplant outcome in a morbidly obese patient with acute myeloblastic leukemia.
We report a case of matched unrelated bone marrow transplant (BMT) in a morbidly obese patient with acute myeloblastic leukaemia. The challenges presented in the management of this case included the calculation of chemotherapy and radiotherapy doses and the acute presentation of obstructive sleep apnea. Despite these difficulties, an ultimately successful outcome was obtained, indicating that although associated with increased risk of peri-transplant morbidity, obesity need not represent a contraindication to BMT.
Ritchie
D S
DS
Department of Clinical Haematology and Medical Oncology, Royal Melbourne Hospital, Australia.
Wirth
A
A
Grigg
A P
AP
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D016026:Bone Marrow Transplantation; D005260:Female; D006085:Graft Survival; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D009767:Obesity, Morbid; D016896:Treatment Outcome; D014916:Whole-Body Irradiation
D000970:Antineoplastic Agents