Ruthenium-catalyzed olefin metathesis in ionic liquids.
[reaction--see text] Ionic liquid 1-butyl-3-methylimidazoliumhexafluorophosphate ([bmim]PF(6)) is described as an effective medium for ring-closing metathesis (RCM) using Grubbs catalysts. When [bmim]PF(6) was used as solvent, the RCM showed high conversions and a broad substrate tolerance. [bmim]PF(6) and the ruthenium catalyst were recycled after extraction of the product in the organic phase for at least three cycles.
Buijsman
R C
RC
Lead Discovery Unit, N.V. Organon, P.O. Box 20, 5340 BH Oss, The Netherlands. rogier.buijsman@organon.com
van Vuuren
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E
Sterrenburg
J G
JG