Simple, efficient chemoenzymatic synthesis of (S)-5-(tert-butyldimethylsilyloxy)-2-cyclohexenone and enantiomeric ketone intermediates of 19-nor-1alpha,25-dihydroxyvitamin D(3).
Kalkote
U R
UR
Division of Organic Chemistry: Technology, National Chemical Laboratory, Pune, India. kalkote@dalton.ncl.res.in
Ghorpade
S R
SR
Chavan
S P
SP
Ravindranathan
T
T
D002117:Calcitriol / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D002384:Catalysis; D003512:Cyclohexanones / Q000138:chemical synthesis; D007659:Ketones / Q000138:chemical synthesis; D008049:Lipase / Q000378:metabolism; D013237:Stereoisomerism
D003512:Cyclohexanones; D007659:Ketones; C083610:1,25-dihydroxy-19-norvitamin D3; D008049:Lipase; D002117:Calcitriol