title: Multi-slice computed tomography as a screening tool for colon cancer, lung cancer and coronary artery disease.
abstract: Recent promising trials that use low-dose CT for the early detection of lung cancer have reinvigorated the interest in screening approaches. At the same time the development of fast image acquisition techniques, such as multislice CT, have sparked renewed interest in cardiac imaging within the radiological community. In addition to special cardiac capabilities, multislice CT has several other features such as high acquisition speed and low-dose requirements that may make this modality a universal radiological screening tool. Non-invasive disease detection is the radiologist's domain. In this paper we identify criteria for effective screening and apply these criteria to screening approaches with multislice CT when used for detection of three disease entities: colon cancer; lung cancer; and cardiovascular disease.
authors.affiliation: Institute of Clinical Radiology, University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81377 Munich, Germany. schoepf@ikra.med.uni-muenchen.de
authors.forename: U J
authors.initials: UJ
authors.lastname: Schoepf
authors.forename: C R
authors.initials: CR
authors.lastname: Becker
authors.forename: N A
authors.initials: NA
authors.lastname: Obuchowski
authors.forename: G F
authors.initials: GF
authors.lastname: Rust
authors.forename: B M
authors.initials: BM
authors.lastname: Ohnesorge
authors.forename: G
authors.initials: G
authors.lastname: Kohl
authors.forename: S
authors.initials: S
authors.lastname: Schaller
authors.forename: M T
authors.initials: MT
authors.lastname: Modic
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
mesh_terms: D003110:Colonic Neoplasms / Q000000981:diagnostic imaging*; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008403:Mass Screening; D014057:Tomography, X-Ray Computed / Q000379:methods*