Hereditary familial vestibular degenerative diseases.
Identification of genes involved in hereditary vestibular disease is growing at a remarkable pace. Mutant mouse technology can be an important tool for understanding the biological mechanism of human vestibular diseases.
Sun
J C
JC
Department of Otolaryngology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. sunj@medicine.wustl.edu
Van Alphen
A M
AM
Wagenaar
M
M
Huygen
P
P
Hoogenraad
C C
CC
Hasson
T
T
Koekkoek
S K
SK
Bohne
B A
BA
De Zeeuw
C I
CI
D000818:Animals; D004398:Dyneins; D005133:Eye Movements; D006801:Humans; D007150:Immunohistochemistry; D051379:Mice; D008817:Mice, Mutant Strains; D000081412:Myosin VIIa; D009218:Myosins / Q000378:metabolism; D015221:Potassium Channels / Q000235:genetics / Q000502:physiology; D012027:Reflex, Vestibulo-Ocular; D051637:Shaker Superfamily of Potassium Channels; D015837:Vestibular Diseases / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology
C000631455:MYO7A protein, human; C000631456:Myo7a protein, mouse; D000081412:Myosin VIIa; D015221:Potassium Channels; D051637:Shaker Superfamily of Potassium Channels; D009218:Myosins; D004398:Dyneins