Remarkably selective iridium catalysts for the elaboration of aromatic C-H bonds.
Arylboron compounds have intriguing properties and are important building blocks for chemical synthesis. A family of Ir catalysts now enables the direct synthesis of arylboron compounds from aromatic hydrocarbons and boranes under "solventless" conditions. The Ir catalysts are highly selective for C-H activation and do not interfere with subsequent in situ transformations, including Pd-mediated cross-couplings with aryl halides. By virtue of their favorable activities and exceptional selectivities, these Ir catalysts impart the synthetic versatility of arylboron reagents to C-H bonds in aromatic and heteroaromatic hydrocarbons.
Cho
Jian-Yang
JY
Department of Chemistry, Michigan State University, East Lansing, MI 48824, USA.
Tse
Man Kin
MK
Holmes
Daniel
D
Maleczka
Robert E
RE
Smith
Milton R
MR
D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D008024:Ligands
D001896:Boron Compounds; D006841:Hydrocarbons, Aromatic; D008024:Ligands; D007495:Iridium; D002244:Carbon; D006859:Hydrogen