[The problem of induced genomic instability in the child body cells under conditions of long-term effect of small radiation doses].
The phenomenological aspects of the genomic instability induced in the descendants of the multi-divided cells having been exposed to the radiation are examined. It is demonstrated that the regularity of the chromosome instability induction do not correspond to the classical conception of the radiation genetics (hit principle and target theory). The mechanisms and the biological significance of this new genetic phenomenon in the child organism under conditions of low-intensive effect of small-dose radiation and its connection with the state of health are discussed.
Suskov
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II
N.I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991 Russia. suskov@vigg.ru
Kuz'mina
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NS
D000328:Adult; D000367:Age Factors; D000818:Animals; D001854:Bone Marrow Cells / Q000528:radiation effects; D002478:Cells, Cultured; D002648:Child; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000528:radiation effects*; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000528:radiation effects; D005260:Female; D005720:Gamma Rays; D016678:Genome; D006801:Humans; D008297:Male; D051379:Mice; D009154:Mutation; D018812:Paternal Exposure; D011210:Power Plants; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000235:genetics*; D018788:Radioactive Hazard Release; D051381:Rats; D013997:Time Factors; D014455:Ukraine; D014466:Ultraviolet Rays
D004247:DNA