High spatial resolution in vivo 2D (1)H magnetic resonance spectroscopic imaging of human muscles with a band-selective technique.
This report demonstrates a 2D (1)H magnetic resonance spectroscopic imaging (MRSI) technique that can address some technical difficulties often encountered in MRS studies of human muscles. A preliminary application of this whole-slice technique in human skeletal muscles demonstrates clearly noticeable differences in (1)H metabolite spectra between different human muscles. This observation illustrates the importance of multi-voxel and high spatial resolution in a heterogeneous environment. This technique is robust, can be easily implemented on a commercial MR scanner, and should prove useful for investigators in both basic and clinical (1)H MRS studies.
Hu
J
J
Department of Radiology, Wayne State University, Detroit, MI 48201, USA. jhu@med.wayne.edu
Jiang
Q
Q
Xia
Y
Y
Zuo
C
C
D000328:Adult; D000368:Aged; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000378:metabolism*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation