title: Intact prototype learning in schizophrenia.
abstract: In this study, we examined executive functions and visual prototype learning in patients with schizophrenia (n=22) and matched healthy control subjects (n=20). The patients demonstrated marked perseveration in the Wisconsin Card Sorting Test (WCST), whereas they successfully learned prototypes of dot-pattern category exemplars. These findings are against the hypothesis of a pure generalized cognitive dysfunction in schizophrenia, providing preliminary evidence for intact neocortical mechanisms related to perceptual classification functions.
authors.affiliation: University of Szeged, Department of Psychiatry, 6725 Semmelweis u. 6, Szeged, Hungary. szkeri@phys.szote.u-szeged.hu
authors.forename: S
authors.initials: S
authors.lastname: Kéri
authors.forename: O
authors.initials: O
authors.lastname: Kelemen
authors.forename: G
authors.initials: G
authors.lastname: Benedek
authors.forename: Z
authors.initials: Z
authors.lastname: Janka
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002540:Cerebral Cortex / Q000503:physiopathology; D003072:Cognition Disorders / Q000209:etiology* / Q000503:physiopathology; D004193:Discrimination Learning; D005260:Female; D006801:Humans; D008297:Male; D010364:Pattern Recognition, Visual; D012559:Schizophrenia / Q000150:complications / Q000503:physiopathology; D012565:Schizophrenic Psychology