Kinetochore function: the complications of becoming attached.
Kinetochores are specialized protein complexes assembled on centromeric DNA that connect to spindle microtubules and mediate proper chromosome segregation during cell division. Recent results have implicated specific kinetochore proteins in microtubule attachment.
Van Hooser
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AA
Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3200, USA. aaronvan@uclink.berkeley.edu
Heald
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R
D005656:Fungal Proteins / Q000378:metabolism*; D018386:Kinetochores / Q000378:metabolism*; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins; D004718:Saccharomycetales / Q000378:metabolism; D008941:Spindle Apparatus / Q000378:metabolism
D005656:Fungal Proteins; D008869:Microtubule-Associated Proteins; C112472:NDC80 protein, S cerevisiae; D009687:Nuclear Proteins; D029701:Saccharomyces cerevisiae Proteins