[Studies on the functional anatomy of Golgi-phobic dendrites of spinal motoneurons in rats--different dendroarchitectures of the motoneurons to slow muscle and fast one].
OBJECTIVE
The functional anatomy of Golgi-phobic dendrites (GBD) of spinal motoneurons (Mn) in rats was studied from their postnatal development.


METHODS
Cholera toxin B subunit conjugated with horseradish peroxidase (CB-HRP) retrograde labelling method was mainly used.


RESULTS
In the extensor digitorum longus Mn pool (EDL-Mn) GBD gradually decrease during development and are only a few in adults. The related value of the surface density of the white matter dendrites, most of them are GBD, of the soleus Mn pool (SOL-Mn) is nearly double than that of EDL-Mn.


CONCLUSIONS
GBD of motoneurons might be related to their action patterns, especially the tonic action of slow muscle, such as the soleus. The hypotheis of dual circuits in motor control, the paralateral circuit on GBD regulates control of tonic action and the core circuit on Golgi-philic dendrites (GLD) and somata regulates phasic action, such as on EDL-Mn, has been further enhanced.
Shi
G
G
Institute of Basic Medical Sciences, CAMS and PUMC, Beijing 100005.
Wan
X
X
Tan
H
H
Yang
T
T
D000818:Animals; D002772:Cholera Toxin; D003712:Dendrites / Q000502:physiology*; D006735:Horseradish Peroxidase; D009046:Motor Neurons / Q000166:cytology / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D013116:Spinal Cord / Q000166:cytology*
C052635:cholera toxin, B subunit-horseradish peroxidase; D002772:Cholera Toxin; D006735:Horseradish Peroxidase