title: NOESY on neurotoxins: NMR and conformational assignments of picrotoxins.
abstract: Nuclear Overhauser effect spectroscopy (NOESY) gave full assignments of the 1H-NMR spectra of the picrotoxane neurotoxins tutin, hyenanchin, picrotoxinin and picrotin, as well as the solution conformations of these compounds, consistent with molecular modelling. Fully assigned 13C-NMR data are reported.
authors.affiliation: New Zealand Institute for Crop and Food Research Ltd, Department of Chemistry, University of Otago, PO Box 56, Dunedin, New Zealand. perryn@crop.cri.nz
authors.forename: N B
authors.initials: NB
authors.lastname: Perry
authors.forename: M
authors.initials: M
authors.lastname: Aiyaz
authors.forename: D S
authors.initials: DS
authors.lastname: Kerr
authors.forename: R J
authors.initials: RJ
authors.lastname: Lake
authors.forename: M T
authors.initials: MT
authors.lastname: Leach
mesh_terms: D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008968:Molecular Conformation; D009498:Neurotoxins / Q000737:chemistry*; D010852:Picrotoxin / Q000031:analogs & derivatives* / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry*; D054830:Sesterterpenes
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings; D009498:Neurotoxins; D010852:Picrotoxin; D012717:Sesquiterpenes; D054830:Sesterterpenes; C442493:hyenanchin; C022961:picrotoxinin; C009614:tutin; C411705:picrotin