title: Current management of premenstrual syndrome and premenstrual dysphoric disorder.
abstract: About 5% of women of reproductive age experience affective or physical premenstrual symptoms that markedly influence work, social activities, or relationships. Prospective charting of symptoms for at least two menstrual cycles is required to facilitate an accurate diagnosis of premenstrual syndrome or premenstrual dysphoric disorder. The optimal treatment plan begins with lifestyle modifications, followed by pharmacotherapy. Evidence from numerous controlled trials has clearly demonstrated that low-dose serotonin reuptake inhibitors, using intermittent or continuous administration, have excellent efficacy with minimal side effects. Modification of the menstrual cycle should be considered only after all other treatment options have failed.
authors.affiliation: Women's Health Concerns Clinic, St. Joseph's Healthcare, Fontbonnne 639, 50 Charlton Avenue East, Hamilton, Ontario L8N 4A6, Canada. mst@mcmaster.ca
authors.forename: L
authors.initials: L
authors.lastname: Born
authors.forename: M
authors.initials: M
authors.lastname: Steiner
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D002118:Calcium / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use*; D019964:Mood Disorders / Q000209:etiology* / Q000628:therapy*; D010789:Phototherapy / Q000379:methods; D008517:Phytotherapy; D011293:Premenstrual Syndrome / Q000523:psychology*; D025101:Vitamin B 6 / Q000627:therapeutic use*; D020950:Vitex
chemical_list: D000928:Antidepressive Agents; D025101:Vitamin B 6; D008274:Magnesium; D002118:Calcium