[Clinic intervention study on urogenital mycoplasma infection of pregnant women].
OBJECTIVE
To explore the hypothesis of pathogenic relationship between urogenital mycoplasma infection and adverse perinatal outcomes.


METHODS
Four hundred and eighty-eight mycoplasma-positive pregnant women detected by culture method were randomly divided into erythromycine-intervention group and non-intervention group. Comparison was made on rate of reverse sero-conversion, of vertical transmission to mycoplasma and adverse perinatal outcomes incidence between groups.


RESULTS
Ureaplasma urealyticum sero-conversion rate and rate of vertical-transmission in intervention group were significantly lower than in non-intervention group (P < 0.05). The incidences rates of preturm labor, post partum fever, puerperal infection and neonate pneumonia in intervention group were significantly lower than in non-intervention group (P < 0.05).


CONCLUSIONS
Erythromycin is effective in control of ureaplasma urealyticum infection among pregnant women through cutting off vertical transmission passway and lowering adverse perinatal outcomes against ureaplasma urealyticum.
Ye
Y
Y
Tongji Hospital, Tongji University, Shanghai, 200065, China.
Tu
S
S
Li
H
H
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004917:Erythromycin / Q000627:therapeutic use*; D005260:Female; D052776:Female Urogenital Diseases / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D009175:Mycoplasma Infections / Q000188:drug therapy* / Q000382:microbiology / Q000635:transmission; D018743:Perinatal Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D004917:Erythromycin