[Immunochemical homology of HIV-1 envelope proteins and human apolipoprotein AI].
Immunochemical homology of envelope HIV proteins and human apolipoprotein A-I was for the first time detected by ELISA. Immunochemical reactions between antibodies to apoA-I and HIV envelope proteins and between apoA-I and anti-HIV antibodies present in the blood of AIDS patients were shown. These data suggest that the homology of surface HIV proteins and human apoA-I can lead to competitive relationships impeding the involvement of human apoA-I in gene expression regulation.
Panin
L E
LE
Kostina
N E
NE
Poteriaeva
O N
ON
Fediuk
N V
NV
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000276:immunology; D016632:Apolipoprotein A-I / Q000276:immunology / Q000378:metabolism*; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D015483:HIV Antibodies / Q000276:immunology; D015699:HIV Envelope Protein gp120 / Q000276:immunology / Q000378:metabolism*; D015700:HIV Envelope Protein gp41 / Q000276:immunology / Q000378:metabolism*; D015497:HIV-1 / Q000378:metabolism*; D006801:Humans; D011485:Protein Binding
D016632:Apolipoprotein A-I; D015483:HIV Antibodies; D015699:HIV Envelope Protein gp120; D015700:HIV Envelope Protein gp41