Adesmia aegiceras: antimicrobial activity and chemical study.
The antimicrobial activity of the ethanolic extract of Adesmia aegiceras was studied by the agar-well diffusion method. Antibacterial activity against Micrococcus luteus and eight pathogenic bacterial strains as well as antifungal activity against Candida albicans, was detected. Bacterial and fungal strains exhibited similar concentration-response curves (EC50 and Rmax values) and similar MIC. The MBC/MIC was about 8. These data would indicate the potential usefulness of the A. aegiceras extract as a microbiostatic, antiseptic or disinfectant agent. Furthermore, chemical study of the bioactive alcoholic extract was performed, which revealed quercetin, isorhamnetin-3-rutinoside, isovitexin, pinitol and chlorogenic acid as its main components.
Agnese
A M
AM
Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Argentina.
Pérez
C
C
Cabrera
J L
JL
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D007887:Fabaceae; D008826:Microbial Sensitivity Tests; D016982:Micrococcus luteus / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018514:Plant Structures / Q000737:chemistry
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010936:Plant Extracts