[Disseminated actinic keratoses. Comparison of topical photodynamic therapy with 5-aminolevulinic acid and topical 5% imiquimod cream].
We report on a 75-year-old woman with skin type I suffering for 20 years from multiple actinic keratoses of areas exposed to the sun. The skin of her forearms was treated on one side with imiquimod 5% cream over 4 weeks and on the contralateral side with photodynamic therapy (PDT) using topical 5-aminolevulinic acid (ALA). Both sides showed good clinical response after 3-months follow-up, suggesting that these modalities can be effectively used for treating widespread multiple actinic keratoses.
Cerburkovas
O
O
Universitätsklinik für Dermatologie und Venerologie, Otto-von-Guericke-Universität Magdeburg.
Krause
M
M
Ulrich
J
J
Bonnekoh
B
B
Gollnick
H
H
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000368:Aged; D000622:Aminolevulinic Acid / Q000008:administration & dosage*; D000634:Aminoquinolines / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D000077271:Imiquimod; D007634:Keratitis / Q000188:drug therapy*; D009824:Ointments; D010778:Photochemotherapy; D010787:Photosensitivity Disorders / Q000188:drug therapy*; D017319:Photosensitizing Agents / Q000008:administration & dosage*; D013997:Time Factors
D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D009824:Ointments; D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid; D000077271:Imiquimod