title: Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients.
abstract: We compared the clinical and laboratory features of human immunodeficiency virus (HIV)- and non-HIV-infected patients with penicilliosis marneffei. HIV-infected patients had a higher incidence of fungemia. A total of 85.7% of the HIV-negative patients had underlying diseases including hematologic malignancies or had received therapy with corticosteroids or cytotoxic agents. By a Penicillium marneffei-specific mannoprotein Mp1p enzyme-linked immunosorbent assay, serum antigen titers were found to be higher in HIV-positive patients, whereas serum antibody levels were found to be higher in HIV-negative patients.
authors.affiliation: Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong.
authors.forename: S S
authors.initials: SS
authors.lastname: Wong
authors.forename: K H
authors.initials: KH
authors.lastname: Wong
authors.forename: W T
authors.initials: WT
authors.lastname: Hui
authors.forename: S S
authors.initials: SS
authors.lastname: Lee
authors.forename: J Y
authors.initials: JY
authors.lastname: Lo
authors.forename: L
authors.initials: L
authors.lastname: Cao
authors.forename: K Y
authors.initials: KY
authors.lastname: Yuen
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000908:Antibodies, Fungal / Q000097:blood; D000946:Antigens, Fungal / Q000032:analysis; D002648:Child; D003470:Culture Media; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016469:Fungemia / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology*; D010407:Penicillium / Q000254:growth & development / Q000302:isolation & purification*
chemical_list: D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D003470:Culture Media