title: Modulating the profit motive to meet needs of the less-developed world.
abstract: The success, despite the problems, of academic/industrial collaborations over the past decade owes much to the profit motive. However, market-driven research and development has little to offer patients in the less-developed world. Some flexibility has already been demonstrated on drugs for orphan (rare or under-researched) diseases. Many diseases in less-developed countries are not rare. Academic researchers should be encouraging the establishment of funding for basic and clinical research that is directed at patients' needs in the less-developed world and that is independent of a commercial ethos.
authors.affiliation: Mario Negri Institute for Pharmacological Research, Bergamo, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Schieppati
authors.forename: G
authors.initials: G
authors.lastname: Remuzzi
authors.forename: S
authors.initials: S
authors.lastname: Garattini
mesh_terms: D000046:Academic Medical Centers / Q000191:economics*; D035843:Biomedical Research; D003906:Developing Countries; D004345:Drug Industry / Q000191:economics*; D006801:Humans; D009965:Orphan Drug Production / Q000191:economics* / Q000331:legislation & jurisprudence; D012106:Research / Q000191:economics*; D014944:World Health Organization