title: [ENU induced mutagenesis-large-scale study of gene mutagenesis and function].
abstract: ENU mutagenesis is becoming one of the most powerful approaches for large-scale study of gene function. The mechanism of ENU mutagenesis, factors that affect mutation rates, the strategies of the ENU mutagenesis, screening for the phenotypes, related researches and recent progresses were introduced.
authors.affiliation: Center of Laboratory Animals, Academy of Military Medical Sciences, Beijing 100071, China.
authors.forename: Y S
authors.initials: YS
authors.lastname: Sun
authors.forename: X
authors.initials: X
authors.lastname: Yang
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D005038:Ethylnitrosourea / Q000633:toxicity*; D005838:Genotype; D006801:Humans; D051379:Mice; D016296:Mutagenesis; D013234:Stem Cells / Q000187:drug effects
chemical_list: D005038:Ethylnitrosourea