Three-year experience with 4-site intradermal booster vaccination with rabies vaccine for postexposure prophylaxis.
For booster vaccination of previously immunized persons with potential exposure to rabies, the World Health Organization recommends 2 doses of cell-culture vaccine administered intramuscularly or intradermally on days 0 and 3. We believe that four 0.1-mL intradermal booster doses given on a single day could be used at no risk to the recipient. We studied use of a single booster vaccination on day 0 followed by four 0.1-mL intradermal doses of cell-culture rabies vaccines, and we determined that this is a safe, convenient, and economical regimen for postexposure treatment of previously vaccinated individuals.
Tantawichien
T
T
Queen Saovabha Memorial Institute and Division of Infectious Diseases, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. tantawichien_terapong@hotmail.com
Tantawichien
T
T
Supit
C
C
Khawplod
P
P
Sitprija
V
V
D000293:Adolescent; D000328:Adult; D018890:Chemoprevention; D006801:Humans; D007117:Immunization, Secondary; D015994:Incidence; D007271:Injections, Intradermal; D007273:Injections, Intramuscular; D011818:Rabies / Q000453:epidemiology / Q000517:prevention & control*; D011819:Rabies Vaccines / Q000008:administration & dosage* / Q000009:adverse effects; D013785:Thailand / Q000453:epidemiology; D014944:World Health Organization
D011819:Rabies Vaccines