title: Assessment of anti-inflammatory effect of 830nm laser light using C-reactive protein levels.
abstract: The anti-inflammatory effect of non-surgical lasers has been proposed previously, however it was not scientifically proven. One method to assess levels of inflammation is the measurement of C-reactive protein (CRP), which is increased with the course of inflammation. The aim of this study was to assess the effect of 830 nm laser irradiation after the removal of impacted third molars using the CRP as the marker of inflammation. Twelve patients were irradiated with 4.8 J of laser light per session 24 and 48 h after surgery. A control group (N = 12) was treated with a sham laser. Blood samples were taken prior to, and 48 and 72 h after surgery. CRP values were more symmetric and better distributed for the irradiated group (0.320 mg/dl) than for the control (0.862.mg/dl) 48 h after surgery, however there was no statistically significant difference. After 72 h, both groups had statistically similar CRP levels (0.272 and 0.608 mg/dl), because of the normal tendency of decreasing CRP levels.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, PUC-RS, Porto Alegre, RS, Brazil.
authors.forename: A C
authors.initials: AC
authors.lastname: Freitas
authors.forename: A L
authors.initials: AL
authors.lastname: Pinheiro
authors.forename: P
authors.initials: P
authors.lastname: Miranda
authors.forename: F A
authors.initials: FA
authors.lastname: Thiers
authors.forename: A L
authors.initials: AL
authors.lastname: Vieira
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000517:prevention & control*; D028022:Low-Level Light Therapy; D008964:Molar, Third / Q000601:surgery; D018709:Statistics, Nonparametric; D014081:Tooth Extraction / Q000009:adverse effects
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein