title: [Infectious endocarditis in France today].
abstract: Infectious endocarditis (IE) is an uncommon condition carrying a relatively high mortality and morbidity. Two epidemiological studies, undertaken eight years apart, provide data allowing an appreciation of changes in the epidemiological and clinical profiles of IE. They show a progressive increase in the age of patients affected by IE and a decrease in percentage of IE on native pathological valves and valvular prostheses, compensated by the increase in incidence of IE occurring in patients with no known underlying cardiac disease. Moreover, there has been a change in microbiological profile, with the emergence of Streptococcus bovis and increase in staphylococcal IE, a decrease in IE due to oral streptococci and an improvement in microbiological diagnosis with negative blood cultures. Finally, from the therapeutic point of view, surgery is used more frequently and at an earlier stage of the disease. The global mortality of IE at the end of the initial hospital period remains 16%.
authors.affiliation: Service de cardiologie, CHU Nancy-Brabois.
authors.forename: C
authors.initials: C
authors.lastname: Selton-Suty
authors.forename: T
authors.initials: T
authors.lastname: Doco-Lecompte
authors.forename: Y
authors.initials: Y
authors.lastname: Juillière
authors.forename: B
authors.initials: B
authors.lastname: Hoen
mesh_terms: D000367:Age Factors; D000368:Aged; D004697:Endocarditis, Bacterial / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D005602:France / Q000453:epidemiology; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009026:Mortality; D011379:Prognosis; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000150:complications; D013290:Streptococcal Infections / Q000150:complications; D016985:Streptococcus bovis / Q000302:isolation & purification / Q000472:pathogenicity