title: Intraradicular space: what happens within roots of infected teeth?
abstract: The pulpo-dentine complex is normally protected from exogenous substances in the oral cavity by the overlying enamel or cementum. Dental caries, dental trauma, enamel/dentine cracks, and restorative procedures commonly breach the integrity of enamel or cementum and may allow infection of the pulpo-dentine complex to occur, possibly leading to pulp and periapical inflammatory disease. Infection of the intraradicular space is a complex and dynamic process involving interactions between host and microbial factors. An understanding of these factors has led to the development of endodontic techniques that offer predictable success.
authors.affiliation: Dental School, University of Otago, Dunedin, New Zealand.
authors.forename: R M
authors.initials: RM
authors.lastname: Love
mesh_terms: D003731:Dental Caries / Q000503:physiopathology; D003739:Dental Cementum / Q000503:physiopathology; D003743:Dental Enamel / Q000293:injuries; D003782:Dental Pulp / Q000382:microbiology / Q000503:physiopathology; D003786:Dental Pulp Cavity / Q000382:microbiology; D003788:Dental Pulp Diseases / Q000382:microbiology / Q000503:physiopathology*; D003793:Dental Restoration, Permanent / Q000009:adverse effects; D003804:Dentin / Q000293:injuries / Q000382:microbiology / Q000503:physiopathology; D006801:Humans; D010483:Periapical Diseases / Q000382:microbiology / Q000503:physiopathology*; D010485:Periapical Periodontitis / Q000209:etiology; D011671:Pulpitis / Q000209:etiology; D012390:Root Canal Therapy; D018677:Tooth Injuries / Q000503:physiopathology; D014092:Tooth Root / Q000382:microbiology / Q000503:physiopathology*; D016896:Treatment Outcome