title: The effects of light therapy on mini-mental state examination scores in demented patients.
abstract: BACKGROUND
  Preliminary evidence suggests that demented patients may experience beneficial effects of light therapy. The authors tested whether bright light therapy (BLT) is capable of improving cognitive functions in patients with Alzheimer-type dementia (AD) or vascular dementia (VD).
  
  
  METHODS
  Twenty-three patients with AD or VD were randomly assigned to either evening BLT or dim light therapy (DLT). Effects of light therapy on cognitive functions were assessed before and after light therapy using Mini-Mental State Examination (MMSE) scores. Body temperature rhythm (BTR) was additionally recorded pre- and posttreatment.
  
  
  RESULTS
  Irrespective of their diagnosis, patients treated with BLT (p =.0012) but not with DLT (p =.73) showed a statistically significant increase in MMSE total scores after light therapy. Evening BLT simultaneously induced a significant phase delay of 56 min on BTR (p =.025).
  
  
  CONCLUSIONS
  Our preliminary results suggest that short-term evening BLT may exert beneficial effects on cognitive functioning in patients with dementia.
authors.affiliation: Department of General Psychiatry, University of Vienna, Vienna, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Graf
authors.forename: C
authors.initials: C
authors.lastname: Wallner
authors.forename: V
authors.initials: V
authors.lastname: Schubert
authors.forename: M
authors.initials: M
authors.lastname: Willeit
authors.forename: W
authors.initials: W
authors.lastname: Wlk
authors.forename: P
authors.initials: P
authors.lastname: Fischer
authors.forename: S
authors.initials: S
authors.lastname: Kasper
authors.forename: A
authors.initials: A
authors.lastname: Neumeister
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000628:therapy*; D001831:Body Temperature / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis*; D015140:Dementia, Vascular / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010789:Phototherapy