title: [Paroxetine augmentation with risperidone in therapy-resistant depression].
abstract: In a 71 years-old patient, a severe therapy-resistant depressive episode without psychotic symptoms was successfully treated by a combination of paroxetine and risperidone. Previously, several different antidepressants were not effective in ameliorating the depressive symptoms which occurred repeatedly over a period of more than ten years.
authors.affiliation: Zentralinstitut für Seelische Gesundheit, Mannheim.
authors.forename: U
authors.initials: U
authors.lastname: Knopf
authors.forename: P
authors.initials: P
authors.lastname: Hubrich-Ungureanu
authors.forename: J
authors.initials: J
authors.lastname: Thome
mesh_terms: D000368:Aged; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D017374:Paroxetine / Q000008:administration & dosage* / Q000009:adverse effects; D012008:Recurrence; D018967:Risperidone / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D017374:Paroxetine; D018967:Risperidone