title: A case of fetal parvovirus B19 myocarditis, terminal cardiac heart failure, and perinatal heart transplantation.
abstract: We report a case of fetal cardiomegaly secondary to myocarditis as a result of intrauterine parvovirus B19 infection. The fetus was delivered through caesarean section because of increasing deterioration of cardiac function at 33 + 3 weeks with reverse flow in the ductus venosus. Four weeks later, a cardiac transplantation was carried out because of therapy-resistant dilative cardiomyopathy. This case shows that fetal parvovirus B19 infection may occur without anemia and myocarditis and does not always result in spontaneous reformation of a dilated heart and normal recovery. It may become the determining prognostic factor for the child.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Kiel, Germany. vkaisenberg@email.uni-kiel.de
authors.forename: C S
authors.initials: CS
authors.lastname: von Kaisenberg
authors.forename: G
authors.initials: G
authors.lastname: Bender
authors.forename: J
authors.initials: J
authors.lastname: Scheewe
authors.forename: S W
authors.initials: SW
authors.lastname: Hirt
authors.forename: M
authors.initials: M
authors.lastname: Lange
authors.forename: J
authors.initials: J
authors.lastname: Stieh
authors.forename: H H
authors.initials: HH
authors.lastname: Kramer
authors.forename: W
authors.initials: W
authors.lastname: Jonat
mesh_terms: D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000209:etiology* / Q000601:surgery*; D005260:Female; D005315:Fetal Diseases / Q000821:virology*; D005865:Gestational Age; D016027:Heart Transplantation; D006801:Humans; D009205:Myocarditis / Q000150:complications / Q000000981:diagnostic imaging / Q000821:virology*; D010322:Parvoviridae Infections / Q000821:virology*; D016732:Parvovirus B19, Human; D011247:Pregnancy; D016216:Ultrasonography, Prenatal