title: Successful cardiac transplantation after Novacor implantation in a HIT II-patient using heparin.
abstract: The anticoagulative management of patients tested positive for heparin-induced thrombocytopenia type II (HIT II) and requiring cardiac surgery has been difficult until now. A special challenge arises, when left ventricular assist devices have to be implanted for bridging to cardiac transplantation. We report on the anticoagulative management of such a patient, based on the consideration of HIT II-pathophysiology and using heparin for Novacor LVAD implantation and cardiac transplantation.
authors.affiliation: Klinik und Poliklinik fur Thorax-, Herz- und Gefässchirurgie, Westfälische Wilhelms Universität Münster, Münster, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Christiansen
authors.forename: U R
authors.initials: UR
authors.lastname: Jahn
authors.forename: J
authors.initials: J
authors.lastname: Meyer
authors.forename: H H
authors.initials: HH
authors.lastname: Scheld
authors.forename: H
authors.initials: H
authors.lastname: Van Aken
authors.forename: D
authors.initials: D
authors.lastname: Hammel
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D002311:Cardiomyopathy, Dilated; D004797:Enzyme-Linked Immunosorbent Assay; D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013921:Thrombocytopenia / Q000139:chemically induced*
chemical_list: D000925:Anticoagulants; D006493:Heparin