title: Hereditary familial vestibular degenerative diseases.
abstract: Identification of genes involved in hereditary vestibular disease is growing at a remarkable pace. Mutant mouse technology can be an important tool for understanding the biological mechanism of human vestibular diseases.
authors.affiliation: Department of Otolaryngology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. sunj@medicine.wustl.edu
authors.forename: J C
authors.initials: JC
authors.lastname: Sun
authors.forename: A M
authors.initials: AM
authors.lastname: Van Alphen
authors.forename: M
authors.initials: M
authors.lastname: Wagenaar
authors.forename: P
authors.initials: P
authors.lastname: Huygen
authors.forename: C C
authors.initials: CC
authors.lastname: Hoogenraad
authors.forename: T
authors.initials: T
authors.lastname: Hasson
authors.forename: S K
authors.initials: SK
authors.lastname: Koekkoek
authors.forename: B A
authors.initials: BA
authors.lastname: Bohne
authors.forename: C I
authors.initials: CI
authors.lastname: De Zeeuw
mesh_terms: D000818:Animals; D004398:Dyneins; D005133:Eye Movements; D006801:Humans; D007150:Immunohistochemistry; D051379:Mice; D008817:Mice, Mutant Strains; D000081412:Myosin VIIa; D009218:Myosins / Q000378:metabolism; D015221:Potassium Channels / Q000235:genetics / Q000502:physiology; D012027:Reflex, Vestibulo-Ocular; D051637:Shaker Superfamily of Potassium Channels; D015837:Vestibular Diseases / Q000235:genetics* / Q000378:metabolism / Q000503:physiopathology
chemical_list: C000631455:MYO7A protein, human; C000631456:Myo7a protein, mouse; D000081412:Myosin VIIa; D015221:Potassium Channels; D051637:Shaker Superfamily of Potassium Channels; D009218:Myosins; D004398:Dyneins