[Anaphylactic shock after injection of patent blue for sentinel lymph node biopsy].
After being diagnosed with a melanoma, an 18-year-old woman developed anaphylactic shock following an intracutaneous injection of patent blue during a sentinel lymph node biopsy procedure. Intracutaneous allergy tests revealed positive reactions with patent blue (Bleu patenté V 'Guerbet') as well as with several anaesthetics and morphine. It was concluded that patent blue was the most probable causative agent for the anaphylactic reaction and that the possibility of such a reaction should be taken into consideration during sentinel node procedures. After a few days the operation was completed under epidural anaesthesia with technetium Tc 99m sulphur colloid being used to detect the sentinel node.
van der Horst
J C
JC
Afd. Dermatologie, Ziekenhuis Rijnstate, Postbus 9555, 6800 TA Arnhem.
de Bock
M J
MJ
Klinkenbijl
J H
JH
D000293:Adolescent; D000707:Anaphylaxis / Q000139:chemically induced*; D004396:Coloring Agents / Q000008:administration & dosage / Q000009:adverse effects*; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007267:Injections; D007271:Injections, Intradermal; D008198:Lymph Nodes / Q000473:pathology*; D008545:Melanoma / Q000473:pathology*; D012394:Rosaniline Dyes / Q000008:administration & dosage / Q000009:adverse effects*; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000473:pathology*; D013671:Technetium Tc 99m Sulfur Colloid
D004396:Coloring Agents; D003287:Contrast Media; D012394:Rosaniline Dyes; D013671:Technetium Tc 99m Sulfur Colloid; C008769:sulfan blue