Modulation of the synchronization between cells in visual cortex by contextual targets.
It has been suggested that synchronization of action potentials encodes diverse features of a single image. However, properties of the synchronization, which occurs on a time scale of approximately 1-5 ms, are still poorly understood. We have tested the modulation of synchronization by manipulating the contextual targets introduced in the surround of the receptive field. Experiments were carried out on anaesthetized cats prepared for multiunit and single-cell recordings in area 17. Initially, a patch of sine-wave drifting grating was positioned over the overlapping receptive fields of several neurons. If this coherent motion produced a significant synchronization in cross-correlograms, contextual targets were added. The first contextual stimuli were two sine-wave patches placed above and below the central compound receptive field. Only the contrast of contextual targets changed. Results show that the larger the differential contrast the higher the synchronization. The second contextual stimulus was a lateral shift of a sine-wave patch. Data show that the wider the distance between the central and peripheral patches the better the synchronization. Furthermore, results suggest that the synchrony pattern computed by cross correlating multiunit recordings from two sites differs when the cross correlation is carried out between individual units belonging to each multiunit recording. Together with our previous results it appears that synchronization is stimulus dependent and its strength increases with larger disparities included in the whole stimulating image.
Bretzner
F
F
Département de Sciences Biologiques, Université de Montréal C.P. 6128, Succursale Centre-ville, Montréal, Québec, Canada H3C 3J7.
Aïtoubah
J
J
Shumikhina
S
S
Tan
Y F
YF
Molotchnikoff
S
S
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002415:Cats; D015350:Contrast Sensitivity / Q000502:physiology; D003344:Cortical Synchronization; D009039:Motion Perception / Q000502:physiology; D009415:Nerve Net / Q000502:physiology; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology*; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology; D012684:Sensory Thresholds / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology*