title: The BIMDA shuttle flight mission:  a low cost microgravity payload.
abstract: This paper presents the design, operation and experiment protocol of the Bioserve sponsored flights of the ITA Materials Dispersion Apparatus Payload (BIMDA) flown on the Space Shuttle on STS-37. The BIMDA payload represents a joint effort between ITA (Instrumentation Technology Associates, Inc.) and Bioserve Space Technologies, a NASA Center for the Commercial Development of Space, to investigate the methods and commercial potential of biomedical and fluid science applications in the microgravity environment of space. The BIMDA payload, flown in a Refrigerator/Incubator Module (R/IM) in the Orbiter middeck, consists of three different devices designed to mix fluids in space; four Materials Dispersion Apparatus (MDA) Minilabs developed by ITA, six Cell Syringes, and six Bioprocessing Modules both developed by NASA JSC and Bioserve. The BIMDA design and operation reflect user needs for late access prior to launch (<24 h) and early access after landing (<2 h). The environment for the payload is temperature controlled by the R/IM. The astronaut crew operates the payload and documents its operation. The temperature of the payload is recorded automatically during flight. The flight of the BIMDA payload is the first of two development flights of the MDA on the Space Shuttle. Future commercial flights of ITA's Materials Dispersion Apparatus on the Shuttle will be sponsored by NASA's Office of Commercial Programs and will take place over the next three years. Experiments for the BIMDA payload include research into the following areas: protein crystal growth, thin film membrane casting, collagen formation, fibrin clot formation, seed germination, enzymatic catalysis, zeolite crystallization, studies of mixing effects of lymphocyte functions, and solute diffusion and transport.
authors.affiliation: ITA Inc., Exton, PA 19341, USA.
authors.forename: J
authors.initials: J
authors.lastname: Holemans
authors.forename: J M
authors.initials: JM
authors.lastname: Cassanto
authors.forename: T W
authors.initials: TW
authors.lastname: Moller
authors.forename: V A
authors.initials: VA
authors.lastname: Cassanto
authors.forename: A
authors.initials: A
authors.lastname: Rose
authors.forename: M
authors.initials: M
authors.lastname: Luttges
authors.forename: D
authors.initials: D
authors.lastname: Morrison
authors.forename: P
authors.initials: P
authors.lastname: Todd
authors.forename: R
authors.initials: R
authors.lastname: Stewart
authors.forename: R Z
authors.initials: RZ
authors.lastname: Korszun
authors.forename: G
authors.initials: G
authors.lastname: Deardorff
mesh_terms: D001709:Biotechnology / Q000295:instrumentation* / Q000379:methods; D003362:Cost-Benefit Analysis; D003460:Crystallization; D004780:Environment, Controlled; D004867:Equipment Design; D011506:Proteins / Q000737:chemistry; D012107:Research Design; D013026:Space Flight / Q000191:economics / Q000295:instrumentation*; D018531:Spacecraft; D014481:United States; D018557:United States National Aeronautics and Space Administration; D014893:Weightlessness
chemical_list: D011506:Proteins