Medical treatment of silent myocardial ischemia.
The pathophysiology of silent ischemia remains unclear, but it is extremely prevalent in patients with coronary artery disease. Stress testing is the preferred method of detection, but Holter monitoring is reliable in recording ischemia during daily life and in evaluating therapy. Prognosis is adversely affected by silent ischemia, whether the patient is symptomatic or asymptomatic. A variety of pharmacologic agents can reduce the ischemic burden, and data suggest that such therapy improves prognosis, although not as much as coronary artery revascularization.
Cohn
P F
PF
Cardiology, State University of New York, Health Sciences Center at Stony Brook, Stony Brook, New York 11794-8171, USA.
D000787:Angina Pectoris / Q000503:physiopathology / Q000628:therapy; D002908:Chronic Disease; D006439:Hemodynamics; D006801:Humans; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis