[Safety and efficacy of an early deambulation protocol after PTCA with an angio-seal device].
BACKGROUND
In order to assess the efficacy and safety of an early deambulation (1-2 h) protocol after coronary angioplasty using the Angio-seal collagen plug, we analyzed a consecutive series of patients treated with this device versus a reference group treated with mechanical compression.


METHODS
Two hundred and seven coronary angioplasty patients were included from February to August 2000. Ninety-eight were treated with mechanical compression and one hundred and nine with the Angio-seal collagen plug. All patients were followed at discharge and fifteen days after surgery.


RESULTS
Eighty percent of the patients receiving the Angio-seal device achieved immediate hemostasis (< 1 min). In patients with mechanical compression hemostasis was achieved within 30 min in 68.3%, whereas 25.5% of patients required more than 40 min. First deambulation in the Angio-seal group was achieved within 2 h in 94.5% of the patients. The incidence of major complications was low in both groups (1 case in the Angio-seal group and 2 in the C-clamp group) without statistically significant differences. The Angio-seal group showed a lower incidence of overall vascular complications as compared to the C-clamp group (4.6% vs. 14.3%; p = 0.02).


CONCLUSIONS
Following our protocol, an early deambulation strategy after coronary angioplasty with the use of the Angio-seal collagen plug was feasible, safe and efficacious.
André
M L
ML
Unidad de Cardiología Intervencionista del Instituto Gallego de Medicina Técnica, Hospital do Meixoeiro, Vigo.
Goicolea
J
J
Argibay
V
V
Vázquez
A
A
Guillén
P
P
Gómez
M
M
Ruiz
R
R
Sanmartín
M
M
Mantilla
R
R
D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D016022:Case-Control Studies; D004434:Early Ambulation / Q000295:instrumentation*; D005263:Femoral Artery; D006488:Hemostasis, Surgical / Q000295:instrumentation*; D006801:Humans; D008875:Middle Aged; D013997:Time Factors