Two cases of bronchial asthma after treatment with amiodarone.
Amiodarone is a highly effective antiarrhythmic agent for the prevention of life-threatening arrhythmias. Two cases are described of patients who developed bronchial asthma after treatment with amiodarone. The bronchial asthma resolved after the dose of amiodarone was decreased in both patients. To our knowledge, an association between amiodarone and severe bronchial asthma has previously been reported only once in the medical literature. Physicians should note that amiodarone may cause bronchospasm in susceptible patients.
Imamura
H
H
First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan. imamura@hsp.md.shinshu-u.ac.jp
Kinoshita
O
O
Maruyama
K
K
Izawa
A
A
Uchikawa
S I
SI
Kumazaki
S
S
Takahashi
W
W
Yokoseki
O
O
Yazaki
Y
Y
Koizumi
T
T
Kubo
K
K
D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008297:Male
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone