Chemotherapy for advanced non-small cell lung cancer.
Chemotherapy for advanced NSCLC in good performance status has survival benefit, reduces tumour symptoms and can improve quality of life. Future challenges include defining the optimal chemotherapy and incorporating the newer agents to improve patients' outcome. In particular treatment of the elderly and patients with poorer performance status need to be developed with more attention being paid to relief of symptoms and minimising treatment toxicity.
Thatcher
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Christie and Wythenshawe Hospitals, Wilmslow Road, M20 4BX, Manchester, UK. linda.aschcroft@christie-tr.nwest.nhs.uk
D000328:Adult; D000367:Age Factors; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000473:pathology; D006304:Health Status; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D016019:Survival Analysis