Immune-mediated haemolytic anaemia in two sibling cats associated with multicentric lymphoblastic infiltration.
Immune-mediated haemolytic anaemia associated with multicentric lymphoblastic infiltration is reported in two sibling cats. Both cats presented at under 16 months of age with clinical signs of acute anaemia. In each case there was autoagglutination, a positive Coombs' test and the anaemia was regenerative. At presentation, both cats were negative for FeLV antigen. In each case, the disease proved fatal within 2 months of the initial diagnosis. In both cases, T-lymphoblastic infiltration of bone marrow, liver and spleen was found at post-mortem examination.
Gunn-Moore
D A
DA
Department of Pathology and Microbiology, University of Bristol, Langford, BS40 5DU, UK.
Day
M J
MJ
Graham
M E
ME
Cue
S M
SM
Harbour
D A
DA
D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D002371:Cat Diseases / Q000175:diagnosis* / Q000276:immunology; D002415:Cats; D003298:Coombs Test / Q000662:veterinary; D017809:Fatal Outcome; D008099:Liver / Q000473:pathology; D008213:Lymphocyte Activation; D008297:Male; D013154:Spleen / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology