Computerised planimetric and stereological analyses of histological and cytological parameters in dysplastic atrophic epithelium and carcinoma.
This report analysed two lesions, of the Oral cavity, (atrophic dysplastic epithelium and oral squamous cell carcinoma) using computerized planimetry and point counting stereological methods. Three cytological, and histological parameters were analysed at a time. Results indicate a significant difference between the cell size, and nucleocytoplasmic ratio's of the two lesions when analysed (P<0.0001). The nuclear area measurement did not differ when the figure for the two lesions were compared. Study confirms the efficacy of objective analyses of tissue pathology of the oral cavity.
Lawoyin
J O
JO
Dept. of Oral Pathology/Oral Medicine, University College Hospital Ibadan, Nigeria.
MacDonald
D G
DG
D000368:Aged; D000369:Aged, 80 and over; D001284:Atrophy; D002452:Cell Count; D002467:Cell Nucleus / Q000473:pathology* / Q000648:ultrastructure*; D048429:Cell Size; D003584:Cytological Techniques / Q000379:methods* / Q000592:standards; D003593:Cytoplasm / Q000473:pathology / Q000648:ultrastructure; D003936:Diagnosis, Computer-Assisted / Q000379:methods* / Q000592:standards; D004848:Epithelium; D005260:Female; D006652:Histological Techniques / Q000379:methods* / Q000592:standards; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D009062:Mouth Neoplasms / Q000145:classification / Q000473:pathology*; D015588:Observer Variation; D011230:Precancerous Conditions / Q000145:classification / Q000473:pathology*