[Pure red cell aplasia after allogeneic peripheral blood stem cell transplantation: a case report and literature review].
OBJECTIVE
To report a case of post-allogeneic peripheral blood stem cell transplantation (allo-PBSCT) pure red cell aplasia(PRCA) and the treatment outcome.


METHODS
A patient with acute non-lymphoblastic leukemia(M2a) was treated with allo-PBSCT. His post-PBSCT PRCA was treated with plasmapheresis(2-3 times weekly) and Epo(3,000 U/day, subcutaneously).


RESULTS
Reticulocyte count (Ret) recovered to 0.01 at day +131 and hemoglobin reached 110 g/L at day +154. Erythroid cells in the bone marrow recovered to 0.25, and BFU-E and CFU-E within normal range. This normalized hematopoiesis remained for over 5 months after the cessation of Epo.


CONCLUSIONS
Post allo-PBSCT PRCA can be successfully treated with plasma exchange and Epo.
Li
C
C
Institute of Hematology and Blood Diseases Hospital, CAMS, PUMC, Tianjin 300020.
Han
M
M
Feng
S
S
D000328:Adult; D004921:Erythropoietin / Q000627:therapeutic use*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D008297:Male; D010951:Plasma Exchange; D012010:Red-Cell Aplasia, Pure / Q000209:etiology* / Q000628:therapy
D004921:Erythropoietin