title: TAFI antigen and D-dimer levels during normal pregnancy and at delivery.
abstract: We have investigated whether the levels of thrombin-activatable fibrinolysis inhibitor (TAFI) were correlated with D-dimer levels during pregnancy and at delivery. From the 10th week of pregnancy to delivery, 519 samples from 144 women (mean age 29.3 +/- 5, range 19-43) were obtained. We confirm the gradual increase of D-dimer levels, and provide reference intervals for D-dimer measurements throughout normal pregnancy. TAFI levels increased moderately during pregnancy but no inverse correlation with D-dimer levels was observed.
authors.affiliation: Department of Gynaecology and Obstetrics, Lausanne University Hospital, Lausanne, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Chabloz
authors.forename: G
authors.initials: G
authors.lastname: Reber
authors.forename: F
authors.initials: F
authors.lastname: Boehlen
authors.forename: P
authors.initials: P
authors.lastname: Hohlfeld
authors.forename: P
authors.initials: P
authors.lastname: de Moerloose
mesh_terms: D002352:Carrier Proteins / Q000097:blood*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D007743:Labor, Obstetric / Q000097:blood; D026901:Membrane Transport Proteins; D011247:Pregnancy / Q000097:blood*; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012044:Regression Analysis; D029701:Saccharomyces cerevisiae Proteins; D018709:Statistics, Nonparametric
chemical_list: C409889:ARN2 protein, S cerevisiae; D002352:Carrier Proteins; D005338:Fibrin Fibrinogen Degradation Products; D026901:Membrane Transport Proteins; D029701:Saccharomyces cerevisiae Proteins; C036309:fibrin fragment D