title: A case of feline primary hypoadrenocorticism.
abstract: A 2-year-old entire female British Shorthair cat was referred to the University of Bristol for investigation of lethargy, weakness, constipation and hypothermia. Clinical examination revealed a profoundly weak, hypovolaemic and hypothermic cat. Serum biochemistry revealed hyponatraemia, hyperkalaemia and hyperphosphataemia and the urine was isosthenuric. Lack of response to exogenous adrenocorticotrophic hormone confirmed a diagnosis of hypoadrenocorticism. Treatment consisted initially of intravenous fluid therapy and subsequently a combination of fludrocortisone and prednisolone per os. At follow-up, 20 months after the initial diagnosis the cat remained stable and free of clinical signs.
authors.affiliation: Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, Summerhall, Edinburgh, EH9 1QH, UK.
authors.forename: S
authors.initials: S
authors.lastname: Tasker
authors.forename: A D
authors.initials: AD
authors.lastname: MacKay
authors.forename: A H
authors.initials: AH
authors.lastname: Sparkes
mesh_terms: D000224:Addison Disease / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000188:drug therapy; D002415:Cats; D003937:Diagnosis, Differential; D005260:Female; D005438:Fludrocortisone / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D008901:Mineralocorticoids / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D008901:Mineralocorticoids; D011239:Prednisolone; D005438:Fludrocortisone