title: Accuracy of stool antigen test in posteradication assessment of Helicobacter pylori infection.
abstract: Our aim was to evaluate the accuracy of HpSA test in the diagnosis of Helicobacter pylori infection after the end of eradication therapy. In all 106 H. pylori-positive patients (55 men and 51 women, mean age 51 years, range 19-82) were treated with a course of eradicating regimen. [13C]Urea breath test (UBT) and HpSA were performed four weeks after stopping the treatment. The diagnostic accuracy of HpSA was evaluated in comparison with the results of [13C]UBT. In 90 patients (85%) H. pylori was eradicated according to [13C]urea breath test. After eradication, sensitivity of HpSA was 87.5%, specificity 95.5%, positive predictive value 77.8%, negative predictive value 97.7%, and diagnostic accuracy 94.3%. HpSA is a valuable test in the posteradication assessment of H. pylori infection.
authors.affiliation: Department of Gastroenterology, Cardarelli Hospital, Napolis, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Manes
authors.forename: A
authors.initials: A
authors.lastname: Balzano
authors.forename: G
authors.initials: G
authors.lastname: Iaquinto
authors.forename: C
authors.initials: C
authors.lastname: Ricci
authors.forename: M M
authors.initials: MM
authors.lastname: Piccirillo
authors.forename: N
authors.initials: N
authors.lastname: Giardullo
authors.forename: A
authors.initials: A
authors.lastname: Todisco
authors.forename: M
authors.initials: M
authors.lastname: Lioniello
authors.forename: D
authors.initials: D
authors.lastname: Vaira
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D001944:Breath Tests; D002247:Carbon Isotopes; D005243:Feces / Q000382:microbiology*; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000188:drug therapy; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014508:Urea
chemical_list: D000942:Antigens, Bacterial; D002247:Carbon Isotopes; D014508:Urea