Identification of HLA-A*11 variant (A*1107) in the Korean population.
We report here a new HLA-A*11 allele, A*1107, identified by sequencing based typing in the Korean population. The full-length sequencing of A*1107 was conducted on cDNA. HLA-A*1107 differs from HLA-A*1101 by a single nucleotide at position 399 of codon 109 in exon3 (TTC-->TTA), leading to an amino acid change from phenylalanine to leucine. But the serological profile of HLA-A*1107 did not exhibit the altered HLA-A11.
Pyo
C W
CW
Catholic Hemopoietic Stem Cell Bank, Seoul, Korea.
Choi
H B
HB
Han
H
H
Hong
Y S
YS
Kim
T G
TG
D000483:Alleles; D000595:Amino Acid Sequence; D001483:Base Sequence; D005805:Genes, MHC Class I; D015234:HLA-A Antigens / Q000235:genetics* / Q000276:immunology; D059870:HLA-A11 Antigen; D006650:Histocompatibility Testing; D006801:Humans; D007723:Korea; D008969:Molecular Sequence Data; D009436:Neural Tube Defects / Q000235:genetics; D020641:Polymorphism, Single Nucleotide; D018807:Polymorphism, Single-Stranded Conformational; D016415:Sequence Alignment
D015234:HLA-A Antigens; D059870:HLA-A11 Antigen