title: Platinum-catalyzed cycloisomerization reactions of enynes.
abstract: PtCl(2) constitutes an efficient and practical catalyst for a set of different atom economical rearrangement reactions of enynes. This includes (i) a formal enyne metathesis reaction delivering 1,3-dienes, (ii) the formation of polycyclic vinylcyclopropane derivatives, and (iii) an unprecedented O-->C allyl shift reaction if unsaturated ethers are employed. Although these transformations produce significantly different structural motifs, they share a common mechanism comprising a cationic manifold triggered by the pi-complexation of Pt(II) onto the alkyne unit of the substrates. Strong experimental support for the proposed mechanism comes from deuterium-labeling studies, a careful analysis of the product distribution pattern, and the fact that in some cases PtCl(2) can be replaced by simple Lewis or Brønsted acids as the catalysts.
authors.affiliation: Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim/Ruhr, Germany. fuerstner@mpi-muelheim.mpg.de
authors.forename: A
authors.initials: A
authors.lastname: Fürstner
authors.forename: F
authors.initials: F
authors.lastname: Stelzer
authors.forename: H
authors.initials: H
authors.lastname: Szillat