title: Gene therapy: a strategy for the treatment of inherited muscle diseases?
abstract: The emergence of new vectors of viral origin (recombinant adeno-associated viruses, second and third generation adenoviruses) and a new potential source of cells for transplantation (muscle-derived stem cells) are broadening the panel of therapeutic options for myopathies. Although the perfect gene-transfer method(s) have not yet been found, recent findings will certainly constitute a strong knowledge base for future clinical trials.
authors.affiliation: Human Genetics Unit, CHUL Research Center, Laval University, Ste-Foy, Quebec, Canada.
authors.forename: P A
authors.initials: PA
authors.lastname: Moisset
authors.forename: J P
authors.initials: JP
authors.lastname: Tremblay
mesh_terms: D000818:Animals; D015316:Genetic Therapy; D006801:Humans; D018482:Muscle, Skeletal / Q000502:physiology; D009135:Muscular Diseases / Q000235:genetics* / Q000628:therapy*