title: Bone and Tl-201 scintigraphy in a case of hereditary multiple exostoses.
abstract: A 17-year-old girl with hereditary multiple exostoses, who was thought to have malignant transformation of an exostotic lesion, was examined by bone and Tl-201 chloride scintigraphy. Scintigraphy showed markedly intense uptake by the lesion, whereas Tl-201 imaging did not. Bone scintigraphy revealed intense to moderate uptake in other exostotic lesions, but none was apparent on the Tl-201 study. The lesion was resected and the histopathologic diagnosis was osteochondroma. Negative findings of Tl-201 scintigraphy may not exclude the possibility of chondrosarcoma, and the utility of this method may be limited. However, Tl-201 scintigraphy appears to have a useful role in differentiating malignant transformation from benign osteochondroma in hereditary multiple exostoses.
authors.affiliation: Department of Radiology, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Tani
authors.forename: S
authors.initials: S
authors.lastname: Tsuchimochi
authors.forename: Y
authors.initials: Y
authors.lastname: Nakabeppu
authors.forename: M
authors.initials: M
authors.lastname: Nakajo
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000000981:diagnostic imaging; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002813:Chondrosarcoma / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005097:Exostoses, Multiple Hereditary / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D011877:Radionuclide Imaging; D013793:Thallium; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes; C027549:thallium chloride; D013793:Thallium