Anti-TNF therapies have eliminated the need for steroids in pediatric Crohn's disease: con. Why use a drug with an unknown long-term safety profile if more established therapies will be effective?
Griffiths
A M
AM
IBD Program, Division of Gastroenterology and Nutrition, The Hospital for Sick Children, Toronto, Ontario, Canada. anne.griffiths@sickkids.on.ca
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D002648:Child; D002986:Clinical Trials as Topic; D003424:Crohn Disease / Q000188:drug therapy*; D006801:Humans; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
D000305:Adrenal Cortex Hormones; D000911:Antibodies, Monoclonal; D014409:Tumor Necrosis Factor-alpha