title: Management of anogenital lichen sclerosus.
abstract: Lichen sclerosus (LS) is a skin condition that affects genital and extra genital epithelia in both males and females of all ages and it may occur in association with other autoimmune disease. Currently, the first line effective treatment is an ultra-potent topical corticosteroid. The long-term sequelae of LS include scarring, malignancy, which is rare, and psychosexual disfunction, which is common.
authors.affiliation: St Johns Institute of Dermatology, St Thomas' Hospital, London, UK.
authors.forename: S M
authors.initials: SM
authors.lastname: Neill
authors.forename: C M
authors.initials: CM
authors.lastname: Ridley
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001004:Anus Diseases / Q000188:drug therapy / Q000523:psychology / Q000601:surgery; D002990:Clobetasol / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000188:drug therapy* / Q000523:psychology / Q000601:surgery; D008297:Male; D010409:Penile Diseases / Q000188:drug therapy / Q000523:psychology / Q000601:surgery; D020018:Sexual Dysfunctions, Psychological / Q000209:etiology / Q000628:therapy; D014845:Vulvar Diseases / Q000188:drug therapy / Q000523:psychology / Q000601:surgery
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D002990:Clobetasol