title: [Cytogenetic defects in lymphocytes of patients with chronic opisthorchiasis concurrent with Epstein-Barr virus persistence].
abstract: Sixty three patients with chronic opisthorchiasis were cytogenetically, serologically, and biochemically studied. Most patients with opisthorchiasis were found to have higher or high titers of antibodies to Epstein-Barr viral antigens. There was a direct correlation between the titers of antibodies to Epstein-Barr virus capsid antigen and the count of cytogenetically damaged cells. The majority of opisthorchiasis patients with superinvasion, hepatic, pancreatic, and oropharyngeal diseases showed a great increase in the titers of antibodies to Epstein-Barr virus antigens and a high persistence and in the cytogenetically damaged lymphocytes. Opisthorchiasis patients with high antibody titers to Epstein-Barr virus capsid antigens showed a considerable decrease in the parameters of the peripheral antioxidative system.
authors.forename: E N
authors.initials: EN
authors.lastname: Il'inskikh
authors.forename: A V
authors.initials: AV
authors.lastname: Lepekhin
authors.forename: S V
authors.initials: SV
authors.lastname: Ryzhov
authors.forename: I N
authors.initials: IN
authors.lastname: Il'inskikh
authors.forename: N N
authors.initials: NN
authors.lastname: Il'inskikh
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D002213:Capsid / Q000276:immunology; D002869:Chromosome Aberrations; D002908:Chronic Disease; D020031:Epstein-Barr Virus Infections / Q000097:blood* / Q000150:complications / Q000821:virology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D009889:Opisthorchiasis / Q000097:blood* / Q000150:complications; D013601:T-Lymphocytes / Q000473:pathology*
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G