title: Evaluation of the efficacy of two leishmanins in asymptomatic dogs.
abstract: There are few studies in dogs concerning leishmanin skin test. We evaluated and compared the efficacy of two leishmanin preparations for the detection of dog Leishmania cellular-mediated immunity. Clinically healthy dogs living in an endemic area were studied. A leishmanin preparation 1 (3 x 10(8) promastigotes/ml) was superior to a leishmanin preparation 2 (5 x 10(6) promastigotes/ml), measured as the percentage of positive reactions and the diameter of the induced induration. The leishmanin skin test is a valuable tool, although the results show that the degree of response, as it has been shown in human beings, depends on the preparation used.
authors.affiliation: Facultat de Veterinària, Departament de Farmacologia i de Terapèutica, Universitat Autònoma de Barcelona, Edifici V, Bellaterra, E-08193 Barcelona, Spain. lsolano@quiro.uab.es
authors.forename: L
authors.initials: L
authors.lastname: Solano-Gallego
authors.forename: J
authors.initials: J
authors.lastname: Llull
authors.forename: M
authors.initials: M
authors.lastname: Arboix
authors.forename: L
authors.initials: L
authors.lastname: Ferrer
authors.forename: J
authors.initials: J
authors.lastname: Alberola
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D004283:Dog Diseases / Q000276:immunology* / Q000469:parasitology; D004285:Dogs; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000662:veterinary; D007111:Immunity, Cellular; D007891:Leishmania; D007896:Leishmaniasis / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D012680:Sensitivity and Specificity; D012867:Skin / Q000276:immunology; D012882:Skin Tests / Q000662:veterinary
chemical_list: D000953:Antigens, Protozoan; C032127:leishmanin