title: [A specific property of microvasomotion in the guinea pig cochlea].
abstract: OBJECTIVE
  To investigate specific property of vasomotion in cochlear microvessels and its response to the endothelium-derived relaxation factor (EDRF).
  
  
  METHODS
  The dynamic changes of cochlea microvessels were observed using intravital microscopy and measured by the microcirculatory image processing system. The frequency and amplitude of vasomotion were analyzed with fast Fourier transform (FFT) according to the diameter changes.
  
  
  RESULTS
  The vasomotion of cochlear arteriole with a small amplitude existed in normal condition. The diameter changed from (10.41 +/- 3.03) microns to (12.29 +/- 1.9) microns with a mean value of (11.2 +/- 2.7) microns. The specific property of vasomotion was characterized by a frequency (0.021 +/- 0.002) Hz and amplitude of (0.37 +/- 0.11) micron. The contraction index was determined as 0.42 +/- 0.17. The vasomotion was significantly enhanced after the administration of EDRF.
  
  
  CONCLUSIONS
  The vasomotion existed in the cochlea and EDRF can increase the cochlear blood flow by improving the vasomotion.
authors.affiliation: First Affiliated Hospital, Henan Medical University, Zhengzhou 450052.
authors.forename: X
authors.initials: X
authors.lastname: Shi
authors.forename: M
authors.initials: M
authors.lastname: Dong
authors.forename: S
authors.initials: S
authors.lastname: Jiang
mesh_terms: D000818:Animals; D001120:Arginine / Q000494:pharmacology*; D001160:Arterioles / Q000187:drug effects; D001783:Blood Flow Velocity; D003051:Cochlea / Q000098:blood supply*; D004912:Erythrocytes / Q000502:physiology; D005260:Female; D006168:Guinea Pigs; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D012039:Regional Blood Flow; D014661:Vasoconstriction / Q000187:drug effects
chemical_list: D001120:Arginine