title: Glucose sensing based on interdigitated array microelectrode.
abstract: A micro glucose sensor consisting of an interdigitated array gold microelectrode was developed. The interdigitated array structure, which has 10 microns band width and 10 microns band gap, was fabricated in a small region (2.5 x 5 mm2) on a quartz substrate. Glucose oxidase was chemically fixed onto the electrode surface through self-assembled monolayer of 11-mercaptoundecanoic acid; ferroceneacetic acid was used as electron mediator. Electrochemical properties of the glucose oxidase-immobilized microelectrode were investigated by cyclic voltammogram measurements. Results confirmed that the reductive ferroceneacetic acid generated at counter electrode diffuses through a narrow band gap (10 microns) and can reach the working electrode surface.
authors.affiliation: Department of Automation Measurement and Control Engineering, Harbin Institute of Technology, No. 92 West Dazhi Street, Harbin 150001, P.R. China.
authors.forename: P
authors.initials: P
authors.lastname: Jin
authors.forename: A
authors.initials: A
authors.lastname: Yamaguchi
authors.forename: F A
authors.initials: FA
authors.lastname: Oi
authors.forename: S
authors.initials: S
authors.lastname: Matsuo
authors.forename: J
authors.initials: J
authors.lastname: Tan
authors.forename: H
authors.initials: H
authors.lastname: Misawa
mesh_terms: D019342:Acetic Acid / Q000737:chemistry; D025802:Electric Capacitance; D004566:Electrodes; D005296:Ferrous Compounds / Q000737:chemistry; D005947:Glucose / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D005949:Glucose Oxidase / Q000737:chemistry; D006046:Gold; D000075163:Metallocenes; D010100:Oxygen / Q000378:metabolism; D055672:Static Electricity; D013997:Time Factors
chemical_list: D005296:Ferrous Compounds; D000075163:Metallocenes; D006046:Gold; D005949:Glucose Oxidase; D005947:Glucose; D019342:Acetic Acid; D010100:Oxygen; C004998:ferrocene