Investigations of the reaction mechanisms of 1,2-indanediones with amino acids.
The reaction mechanisms of amino acids with a new class of fluorogenic reagents were investigated. The structures of colored and fluorescent species formed in these reactions were partially confirmed by experimental evidence. Reaction intermediates, C-N-C 1,3-dipoles derived from imines, were trapped with dipolarophiles in 3 + 2 cycloadditions to form spiropyrrolidines.
Petrovskaia
O
O
Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, PA 19104-6323, USA.
Taylor
B M
BM
Hauze
D B
DB
Carroll
P J
PJ
Joullié
M M
MM
D000596:Amino Acids / Q000737:chemistry*; D007189:Indans / Q000737:chemistry*; D011759:Pyrrolidines / Q000737:chemistry; D013141:Spiro Compounds / Q000737:chemistry
C413384:1,2-indanedione; D000596:Amino Acids; D007189:Indans; D011759:Pyrrolidines; D013141:Spiro Compounds