title: Estimation of left ventricular recovery level based on the motor current waveform analysis on circulatory support with centrifugal blood pump.
abstract: In a mock circulatory loop simulating the left heart bypass using a centrifugal blood pump, analysis of the motor current waveform of the centrifugal pump was performed to derive a useful parameter to evaluate the status of ventricular function. The relationship between the peak, amplitude, and the peak of the fundamental frequency of the power spectral density of the periodic motor current waveform (MCpsdP) that reflected the pulsatile ventricular pressure, and the peak of the left ventricular pressure (LVP) was examined. Although both peak and amplitude of the motor current waveform showed an excellent correlation with the peak LVP, they failed to predict the opening of the aortic valve. The MCpsdP that corresponds to the frequency of the heart rate showed an excellent correlation with the peak LVP throughout the LVP levels, but the slope between them changed with the opening of the aortic valve. Thus, it is possible to follow the change in the LVP and detect even the opening of the aortic valve, and, hence, the recovery of the left ventricle. However, the slope of the linear regression equation varied, depending on the pump speed. This result implies that the MCpsdP can be possibly used to follow the change of ventricular function during circulatory assistance with a centrifugal blood pump as well as to control the pump speed in response to varying ventricular function.
authors.affiliation: Department of Applied Electronic Engineering, Tokyo Denki University, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Uemura
authors.forename: N
authors.initials: N
authors.lastname: Watanabe
authors.forename: K
authors.initials: K
authors.lastname: Ohuchi
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: Y
authors.initials: Y
authors.lastname: Fukui
authors.forename: T
authors.initials: T
authors.lastname: Sakamoto
authors.forename: S
authors.initials: S
authors.lastname: Takatani
mesh_terms: D002498:Centrifugation; D004867:Equipment Design; D006339:Heart Rate / Q000502:physiology; D006353:Heart-Assist Devices; D018056:Hemorheology; D016014:Linear Models; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D012815:Signal Processing, Computer-Assisted; D016277:Ventricular Function, Left / Q000502:physiology*; D017725:Ventricular Pressure