Psychiatric genetics: a frightful chromosome.
A duplication of part of chromosome 15q, apparently inherited in a non-Mendelian fashion, has been found to be strongly associated with phobic disorders. This unusual genetic mechanism may partly explain the heritability of phobias and other complex traits.
Flint
J
J
Wellcome Trust Centre for Human Genetics, University of Oxford, OX3 7BN, UK. jf@molbiol.ox.ac.uk
D002869:Chromosome Aberrations; D002884:Chromosomes, Human, Pair 15; D020440:Gene Duplication; D008040:Genetic Linkage; D006801:Humans; D007593:Joint Instability / Q000235:genetics; D010698:Phobic Disorders / Q000235:genetics*