title: Cyt1Aa from Bacillus thuringiensis subsp. israelensis is toxic to the diamondback moth, Plutella xylostella, and synergizes the activity of Cry1Ac towards a resistant strain.
abstract: The Bacillus thuringiensis subsp. israelensis cytolytic protein Cyt1Aa was found to be toxic to an insecticide-susceptible laboratory population of Plutella xylostella. Cry1Ac-resistant populations of P. xylostella showed various degrees of resistance to Cyt1Aa. Cyt1Aa/Cry1Ac mixtures showed a marked level of synergism in the Cry1Ac-resistant populations.
authors.affiliation: Department of Biological Sciences, Imperial College of Science, Technology and Medicine, Silwood Park, Ascot, Berkshire SL5 7PY, United Kingdom.
authors.forename: A H
authors.initials: AH
authors.lastname: Sayyed
authors.forename: N
authors.initials: N
authors.lastname: Crickmore
authors.forename: D J
authors.initials: DJ
authors.lastname: Wright
mesh_terms: D000818:Animals; D001413:Bacillus thuringiensis / Q000378:metabolism*; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins / Q000378:metabolism / Q000633:toxicity*; D001427:Bacterial Toxins; D004357:Drug Synergism; D004731:Endotoxins / Q000378:metabolism / Q000633:toxicity*; D006460:Hemolysin Proteins; D007305:Insecticide Resistance; D009036:Moths / Q000187:drug effects
chemical_list: D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004731:Endotoxins; D006460:Hemolysin Proteins; C030956:insecticidal crystal protein, Bacillus Thuringiensis