title: Development of hypertensive status in NISAG rats reared by normotensive Wistar rats.
abstract: Parameters of the cardiovascular system and the content of corticosterone, thyrotrophin, thyroxin, and triiodothyronine in the plasma, and norepinephrine in the myocardium were determined in male NISAG rats (hereditary stress-induced arterial hypertension) reared by normotensive Wistar rats. Cross-rearing of hypertensive rat pups by normotensive females attenuated arterial hypertension with a tendency to normalization of the examined parameters. This confirms the possibility of modifying hypertensive phenotype by changing the conditions of the early postnatal development.
authors.affiliation: Institute of Physiology, Siberian Division of the Russian Academy of Medical Science.
authors.forename: G S
authors.initials: GS
authors.lastname: Yakobson
authors.forename: A R
authors.initials: AR
authors.lastname: Antonov
authors.forename: A L
authors.initials: AL
authors.lastname: Markel'
authors.forename: S Y
authors.initials: SY
authors.lastname: Amstislavskii
authors.forename: A G
authors.initials: AG
authors.lastname: Taranov
authors.forename: M G
authors.initials: MG
authors.lastname: Yakobson
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001794:Blood Pressure; D003345:Corticosterone / Q000097:blood; D004562:Electrocardiography; D005260:Female; D006973:Hypertension / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D066298:In Vitro Techniques; D008297:Male; D009638:Norepinephrine / Q000032:analysis; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine; D003345:Corticosterone; D009638:Norepinephrine