title: Prenatal exposure to magnetic field increases dopamine levels in the striatum of offspring.
abstract: 1. The putative effects of prenatal exposure to magnetic field (MF) have recently received much interest. In the present study, mice were exposed to a MF of 50 mT during gestation (0-19 days). 2. After the exposure was terminated, mothers and offspring were returned to normal laboratory conditions. We then determined changes in striatal levels of dopamine (DA) and its metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) in the offspring. 3. Our results indicate that prenatal exposure to MF increases levels of DA and DOPAC in the striatum at 4, 8 and 12 weeks postnatally.
authors.affiliation: Neurotoxicology Program, College of Pharmacy, Kangwon National University, Korea Institute of Drug Abuse, Chunchon.
authors.forename: B C
authors.initials: BC
authors.lastname: Lee
authors.forename: G
authors.initials: G
authors.lastname: Bing
authors.forename: W K
authors.initials: WK
authors.lastname: Jhoo
authors.forename: J M
authors.initials: JM
authors.lastname: Yoon
authors.forename: K S
authors.initials: KS
authors.lastname: Kang
authors.forename: E J
authors.initials: EJ
authors.lastname: Shin
authors.forename: W K
authors.initials: WK
authors.lastname: Kim
authors.forename: K H
authors.initials: KH
authors.lastname: Ko
authors.forename: H C
authors.initials: HC
authors.lastname: Kim
mesh_terms: D015102:3,4-Dihydroxyphenylacetic Acid / Q000378:metabolism; D000818:Animals; D003342:Corpus Striatum / Q000196:embryology / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D005333:Fetus / Q000378:metabolism; D008280:Magnetics / Q000009:adverse effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
chemical_list: D015102:3,4-Dihydroxyphenylacetic Acid; D004298:Dopamine