title: [Selective sentinel node biopsy in melanoma using preoperative lymphoscintigraphy location and intraoperative detection gamma probe].
abstract: BACKGROUND
  The experience in detection of sentinel lymph node in melanoma using preoperative scintigraphy and intraoperative gamma probe is referred.
  
  
  METHODS
  We studied 60 patients with stage I-II melanoma who underwent sentinel lymph node biopsy performed using 99m-Tc-labelled sulphur colloid as radioactive tracer. A preoperative scintigraphy was performed and intraoperative gamma probe was used to localize the sentinel node in all cases. Scintigraphy results, effectiveness of intraoperative detection (technical efficacy), pathological results, and follow-up have been studied.
  
  
  RESULTS
  Preoperative detection was 98.3% and the mean basin detected was 1.17. There were multiple basins especially when melanomas were on the trunk. Technical efficacy was 98.4% and intraoperative detection was more difficult in parotid gland region. HMB-45 immunohistochemical staining was essential in pathological studies, in whom 10% were positives. Lymphadenectomy could be avoided in 90% of the patients. Recurrences were not detected during follow-up and metastases were found only in non biopsied cases. Sentinel node biopsy morbidity was significative lesser than that of lymphadenectomy.
  
  
  CONCLUSIONS
  Preoperative scintigraphy and intraoperative gamma probe use to localize sentinel node in melanoma have a high efficacy. They can reveal multiple basins and they allow a more selective surgical approach and a minimal dissection.
authors.affiliation: Cirugía General y del Aparato Digestivo I, Hospital Universitario Virgen de la Arrixaca. Murcia, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Piñero Madrona
authors.forename: J
authors.initials: J
authors.lastname: Martínez Escribano
authors.forename: F
authors.initials: F
authors.lastname: Nicolás Ruiz
authors.forename: E
authors.initials: E
authors.lastname: Martínez Barba
authors.forename: M
authors.initials: M
authors.lastname: Canteras Jordana
authors.forename: J M
authors.initials: JM
authors.lastname: Rodríguez González
authors.forename: P
authors.initials: P
authors.lastname: Sánchez Pedreño
authors.forename: J L
authors.initials: JL
authors.lastname: Navarro Fernández
authors.forename: J
authors.initials: J
authors.lastname: Frías Iniesta
authors.forename: J
authors.initials: J
authors.lastname: Bermejo López
authors.forename: P
authors.initials: P
authors.lastname: Parrilla Paricio
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care; D008198:Lymph Nodes / Q000000981:diagnostic imaging* / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000556:secondary*; D011300:Preoperative Care; D011877:Radionuclide Imaging; D021701:Sentinel Lymph Node Biopsy