title: Histaminergic regulation of smooth muscles in rabbit pulmonary arteries.
abstract: Histaminergic contractile reactions of smooth muscles in rabbit lobar pulmonary arteries were studied using in vitro mechanographic technique. Histamine via activation of H-receptors induced a dose-dependent constriction of smooth muscle segments, while endothelium inhibited histamine-induced contractile reactions. Histamine increased sensitivity of smooth muscle cells in pulmonary artery to sodium nitroprusside.
authors.affiliation: Siberian State Medical University, Tomsk. kapil@aport.ru
authors.forename: L V
authors.initials: LV
authors.lastname: Kapilevich
authors.forename: Y D
authors.initials: YD
authors.lastname: Anfinogenova
authors.forename: A V
authors.initials: AV
authors.lastname: Nosarev
authors.forename: M B
authors.initials: MB
authors.lastname: Baskakov
authors.forename: I V
authors.initials: IV
authors.lastname: Kovalev
authors.forename: E Y
authors.initials: EY
authors.lastname: D'yakova
authors.forename: M A
authors.initials: MA
authors.lastname: Medvedev
mesh_terms: D000818:Animals; D046508:Culture Techniques; D004155:Diphenhydramine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects / Q000502:physiology; D006632:Histamine / Q000494:pharmacology*; D007537:Isometric Contraction; D009119:Muscle Contraction / Q000187:drug effects; D009126:Muscle Relaxation / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology*; D009599:Nitroprusside / Q000494:pharmacology; D011188:Potassium / Q000494:pharmacology; D011651:Pulmonary Artery / Q000187:drug effects / Q000502:physiology*; D011817:Rabbits; D013314:Stress, Mechanical; D014661:Vasoconstriction / Q000187:drug effects; D014664:Vasodilation / Q000187:drug effects
chemical_list: D009599:Nitroprusside; D006632:Histamine; D004155:Diphenhydramine; D011188:Potassium