title: Drug use and sexual risk behavior among gay and bisexual men who attend circuit parties: a venue-based comparison.
abstract: BACKGROUND
  HIV risk behavior among urban gay/bisexual men has recently increased. High-risk sexual activity and drug use may be particularly high during circuit party (CP) weekends, during which gay/bisexual men congregate for social activities and dancing.
  
  
  OBJECTIVE
  To compare prevalence of risk behaviors during CP weekends with those during non-CP weekends.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  295 gay/bisexual men from the San Francisco Bay Area.
  
  
  METHODS
  Drug use and sexual risk behavior during a San Francisco CP weekend, a CP weekend held in another geographic area (distant weekends), and two non-CP weekends.
  
  
  RESULTS
  During their most recent distant CP weekend, 80% of participants used methylenedioxymethamphetamine (ecstasy), 66% ketamine, 43% crystal methamphetamines, 29% gamma-hydroxybutyrate or gamma-butyrolactone (GHB/GBL), 14% sildenafil (Viagra), and 12% amyl nitrites (poppers); 53% used four or more drugs. Drug use prevalence was greater during CP than non-CP weekends ( p <.001). Unprotected anal sex with partners of unknown or opposite HIV serostatus was most prevalent during distant CP weekends, reported by 21% of HIV-positive and 9% of HIV-negative participants. In multivariate analysis, predictors of unprotected anal sex with opposite or unknown HIV serostatus partners included being HIV-positive (odds ratio [OR], 3.2; 95% confidence interval [CI], 1.4-7.5), and weekend use of crystal methamphetamines (OR 2.4; 95% CI, 1.1-4.9), sildenafil (OR, 3.8; 95% CI, 2.0-7.3), and amyl nitrites (OR, 2.2; 95% CI, 1.3-4.0).
  
  
  CONCLUSIONS
  Prevalence of high-risk activity during these weekends suggests significant potential for HIV transmission in this population. Public health programs in communities hosting CPs should aim to reduce rates of drug use and sexual risk behavior among CP participants, especially HIV-positive men.
authors.affiliation: HIV Research Branch, San Francisco Department of Public Health, San Francisco, California 94102-6033, USA. Grant_Clolfax@dph.sf.ca.us
authors.forename: G N
authors.initials: GN
authors.lastname: Colfax
authors.forename: G
authors.initials: G
authors.lastname: Mansergh
authors.forename: R
authors.initials: R
authors.lastname: Guzman
authors.forename: E
authors.initials: E
authors.lastname: Vittinghoff
authors.forename: G
authors.initials: G
authors.lastname: Marks
authors.forename: M
authors.initials: M
authors.lastname: Rader
authors.forename: S
authors.initials: S
authors.lastname: Buchbinder
mesh_terms: D000328:Adult; D001727:Bisexuality; D003430:Cross-Sectional Studies; D015658:HIV Infections / Q000453:epidemiology*; D006693:Holidays; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D012309:Risk-Taking; D012495:San Francisco / Q000453:epidemiology; D012725:Sexual Behavior; D019966:Substance-Related Disorders / Q000453:epidemiology*; D011795:Surveys and Questionnaires