One case each of recurrent meningitis and hemoperitoneum infection with Ralstonia mannitolilytica.
Two clinical cases of infection with Ralstonia mannitolilytica are described: a recurrent meningitis on an implanted intraventricular catheter and an infected hemoperitoneum as a complication of a cholangiocarcinoma. The strains were first misidentified as Pseudomonas fluorescens and Burkholderia cepacia. Further testing lead to the identification as Ralstonia pickettii biovar 3/"thomasii," which was recently shown to represent a separate species, R. mannitolilytica (List editor N. Weiss, Int. J. Syst. Evol. Microbiol. 51:795-796, 2001), originally described as R. mannitolytica (De Baere et al., Int. J. Syst. Evol. Microbiol. 51:547-558, 2001). R. mannitolilytica can be distinguished from all described Ralstonia species by its acidification of D-arabitol and mannitol and by its lack of nitrate reduction and of alkalinization of tartrate. In order to determine the true prevalence of infections with this species, colistin-resistant "P. fluorescens" strains and strains growing on B. cepacia selective medium deserve further attention.
Vaneechoutte
M
M
Department of Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium. Mario.Vaneechoutte@rug.ac.be
De Baere
T
T
Wauters
G
G
Steyaert
S
S
Claeys
G
G
Vogelaers
D
D
Verschraegen
G
G
D000328:Adult; D020562:Betaproteobacteria / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D002408:Catheters, Indwelling / Q000009:adverse effects; D002552:Cerebral Ventricles; D018281:Cholangiocarcinoma / Q000150:complications; D004275:DNA, Ribosomal / Q000032:analysis; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006465:Hemoperitoneum / Q000382:microbiology*; D006801:Humans; D016920:Meningitis, Bacterial / Q000382:microbiology*; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012008:Recurrence; D017422:Sequence Analysis, DNA
D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S