Familial resemblance of bone mineral density between females 18 years and older and their mothers.
Potential determinants of bone mass were investigated in a group of 70 young females (mean age 26.6 years), daughters of women studied in premenopause. Nutritional data, leisure physical activity level, lifestyle habits as well as familial similarities were assessed. The daughters' bone mineral density (BMD), measured by dual-energy absorptiometry, was significantly correlated with their body mass index (BMI) (r = 0.22), dietary vitamin D intake (r = 0.19) and their mothers' BMD (r = 0.44). Multiple regression analysis indicated that only the mothers' BMD remained an independent predictor of bone mass. Mother-daughter correlations were also observed for body weight (r = 0.24), height (r = 0.39), BMI (r = 0.29), dietary calcium intake (r = 0.20), and calcium (r = 0.20) or vitamin D (r = 0.25) intakes from dairy products. Hence, these observations support the evidence that mothers' BMD is the strongest predictor of bone mass of young women in their third decade.
Picard
D
D
Department of Nuclear Medicine, Hôpital Saint-Luc and Université de Montréal, Montreal, QC.
Imbach
A
A
Couturier
M
M
Lepage
R
R
Picard
M
M
D000328:Adult; D001823:Body Composition / Q000235:genetics*; D001827:Body Height / Q000235:genetics; D015992:Body Mass Index; D001835:Body Weight / Q000235:genetics; D015519:Bone Density / Q000235:genetics*; D002170:Canada; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008875:Middle Aged; D009035:Mothers; D015596:Nutrition Assessment; D010024:Osteoporosis / Q000235:genetics*; D010375:Pedigree; D017697:Premenopause / Q000502:physiology; D012044:Regression Analysis