Studies on constituents from Chamaecyparis pisifera and antibacterial activity of diterpenes.
In the course of our research for biologically active constituents from coniferous plants, a chromone derivative (1) and an abietane derivative (2) were isolated along with several diterpenes from Chamaecyparis pisifera. Structures of the new compounds were determined to be 5,7-dihydroxy-2-(1-acetyl-2-methoxycarbonylethyl)-chromone and rel-(8R,10R,20S)-8,10,20-trihydroxy-9(10-->20)-abeo-abieta-9,13-dien-12-one by means of spectral methods including two-dimensional NMR experiments. Some of these abietane-type compounds isolated from this plants showed antibacterial activitv against the gram-positive bacteria Staphylococcus aureus and Bacillus subtilis.
Xiao
D
D
College of Forestry and Horticulture, Sichuan Agricultural University Yaan, PR China.
Kuroyanagi
M
M
Itani
T
T
Matsuura
H
H
Udayama
M
M
Murakami
M
M
Umehara
K
K
Kawahara
N
N
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D029780:Chamaecyparis / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry
D000900:Anti-Bacterial Agents; D004224:Diterpenes; D010936:Plant Extracts