title: Stimulation of the growth of human tumor by low-power laser irradiation.
abstract: We studied the effect of low-power laser on the growth of human gastric adenocarcinoma transplanted to athymic mice. Irradiation shortened the latency of tumor growth in recipients from 4-6 months to 21-24 days. After 17 serial passages on athymic mice, the size of tumor node in irradiated recipients on day 33 after transplantation was 161.1 mm(3) (vs. 10.2 mm(3) in nonirradiated mice). These findings suggest that low-power laser irradiation can stimulate the growth of metastases in patients with a history of malignancy.
authors.affiliation: Department of Plastic and Reconstruction Surgery, University of California at Los Angeles School of Medicine, USA.
authors.forename: E
authors.initials: E
authors.lastname: Revazova
authors.forename: I
authors.initials: I
authors.lastname: Bryzgalov
authors.forename: I S
authors.initials: IS
authors.lastname: Ivanov
authors.forename: J
authors.initials: J
authors.lastname: Sebastian
authors.forename: G
authors.initials: G
authors.lastname: Keller
authors.forename: J
authors.initials: J
authors.lastname: Watson
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000818:Animals; D002455:Cell Division / Q000528:radiation effects; D006801:Humans; D007834:Lasers; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D011829:Radiation Dosage; D013274:Stomach Neoplasms / Q000473:pathology*; D013997:Time Factors