title: Childhood cancer and parental occupation in the Swedish Family-Cancer Database.
abstract: We used the nationwide Swedish Family-Cancer Database to analyze the risk for common childhood tumors in offspring in relation to parental occupation recorded in the census of 1960. A total of 8158 cancer cases, diagnosed before age 15 between years 1958 and 1996, were included. Standardized incidence ratios were calculated using 52 different parental occupations. Among the maternal occupations, seven were associated with the risk of cancer in offspring. Assistant nurses had an excess of children with leukemia and connective tissue and colon cancers. Children of female cooks had brain cancers at a rate greater than expected. Fifteen different malignancies were associated with children of male workers. Shoe and leathers workers' children had excesses of many tumors. Among the other paternal occupations associated with childhood tumors, miners, quarrymen, and hairdressers were likely to be exposed to harmful dusts and chemicals.
authors.affiliation: Department of Biosciences at Novum, Karolinska Institute, Huddinge, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Mutanen
authors.forename: K
authors.initials: K
authors.lastname: Hemminki
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology; D016273:Occupational Exposure; D009790:Occupations; D010290:Parents; D016012:Poisson Distribution; D012307:Risk Factors; D013548:Sweden / Q000453:epidemiology