Patients with congenital abnormality of platelet aggregation induced by Ca(2+) ionophores may have a defect of the platelet P2Y(12) receptor for ADP.
Cattaneo
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M
Lecchi
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A
D000244:Adenosine Diphosphate / Q000097:blood; D001791:Blood Platelet Disorders / Q000097:blood*; D000001:Calcimycin / Q000494:pharmacology; D006801:Humans; D007476:Ionophores / Q000494:pharmacology; D008565:Membrane Proteins; D010974:Platelet Aggregation / Q000502:physiology*; D018048:Receptors, Purinergic P2 / Q000097:blood*; D058925:Receptors, Purinergic P2Y12
D007476:Ionophores; D008565:Membrane Proteins; C548576:P2RY12 protein, human; D018048:Receptors, Purinergic P2; D058925:Receptors, Purinergic P2Y12; D000001:Calcimycin; D000244:Adenosine Diphosphate