title: Sarcoma associated with silver coated mechanical heart valve prosthesis.
abstract: Sarcomas can develop in association with foreign material (eg, from Dacron vascular prostheses). We report on a left atrial rhabdomyosarcoma that developed within 1 year of mitral valve replacement by a Silzone-coated St. Jude Medical mechanical heart valve. Tumor resection and redo valve replacement were done. Six months later the patient was alive, but an echocardiogram showed tumor recurrence. Although this is a single case, an association between heart valve prostheses and malignant tumors should be considered.
authors.affiliation: Heart and Diabetes Centre Mecklenburg-Vorpommern, Clinic of Cardiothoracic and Vascular Surgery, Karlsburg, Germany. grubitzsch@t-online.de
authors.forename: H
authors.initials: H
authors.lastname: Grubitzsch
authors.forename: H G
authors.initials: HG
authors.lastname: Wollert
authors.forename: L
authors.initials: L
authors.lastname: Eckel
mesh_terms: D020099:Coated Materials, Biocompatible; D005260:Female; D006325:Heart Atria; D006338:Heart Neoplasms / Q000209:etiology*; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D011474:Prosthesis Design; D012208:Rhabdomyosarcoma / Q000209:etiology*; D012834:Silver
chemical_list: D020099:Coated Materials, Biocompatible; D012834:Silver