Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients.
We compared the clinical and laboratory features of human immunodeficiency virus (HIV)- and non-HIV-infected patients with penicilliosis marneffei. HIV-infected patients had a higher incidence of fungemia. A total of 85.7% of the HIV-negative patients had underlying diseases including hematologic malignancies or had received therapy with corticosteroids or cytotoxic agents. By a Penicillium marneffei-specific mannoprotein Mp1p enzyme-linked immunosorbent assay, serum antigen titers were found to be higher in HIV-positive patients, whereas serum antibody levels were found to be higher in HIV-negative patients.
Wong
S S
SS
Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong.
Wong
K H
KH
Hui
W T
WT
Lee
S S
SS
Lo
J Y
JY
Cao
L
L
Yuen
K Y
KY
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000908:Antibodies, Fungal / Q000097:blood; D000946:Antigens, Fungal / Q000032:analysis; D002648:Child; D003470:Culture Media; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016469:Fungemia / Q000175:diagnosis / Q000382:microbiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology*; D010407:Penicillium / Q000254:growth & development / Q000302:isolation & purification*
D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D003470:Culture Media