title: Identification of Mycobacterium avium subsp. paratuberculosis in biopsy specimens from patients with Crohn's disease identified by in situ hybridization.
abstract: Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract of unknown etiology. We report on the presence of cell wall-deficient Mycobacterium avium subsp. paratuberculosis in 35 of 48 paraffin-embedded tissue specimens from 33 patients with Crohn's disease by in situ hybridization with IS900 as a probe.
authors.affiliation: Dipartimento di Scienze Biomediche, Sezione di Microbiologia Sperimentale e Clinica, Università degli studi di Sassari, 07100 Sassari, Italy. sechila@ssmain.uniss.it
authors.forename: L A
authors.initials: LA
authors.lastname: Sechi
authors.forename: M
authors.initials: M
authors.lastname: Mura
authors.forename: F
authors.initials: F
authors.lastname: Tanda
authors.forename: A
authors.initials: A
authors.lastname: Lissia
authors.forename: A
authors.initials: A
authors.lastname: Solinas
authors.forename: G
authors.initials: G
authors.lastname: Fadda
authors.forename: S
authors.initials: S
authors.lastname: Zanetti
authors.forename: M
authors.initials: M
authors.lastname: Manuela
authors.forename: T
authors.initials: T
authors.lastname: Francesco
authors.forename: L
authors.initials: L
authors.lastname: Amelia
authors.forename: S
authors.initials: S
authors.lastname: Antonello
authors.forename: F
authors.initials: F
authors.lastname: Giovanni
authors.forename: Z
authors.initials: Z
authors.lastname: Stefania
mesh_terms: D001706:Biopsy; D003424:Crohn Disease / Q000382:microbiology*; D015342:DNA Probes; D004251:DNA Transposable Elements / Q000235:genetics*; D004064:Digestive System / Q000382:microbiology*; D006801:Humans; D017403:In Situ Hybridization; D016927:Mycobacterium avium subsp. paratuberculosis / Q000145:classification* / Q000235:genetics
chemical_list: D015342:DNA Probes; D004251:DNA Transposable Elements