title: Estimating historical respirable crystalline silica exposures for Chinese pottery workers and iron/copper, tin, and tungsten miners.
abstract: Collaborative studies of Chinese workers, using over four decades of dust monitoring data, are being conducted by the National Institute for Occupational Safety and Health (NIOSH) and Tongji Medical University in China. The goal of these projects is to establish exposure-response relationships for the development of diseases such as silicosis or lung cancer in cohorts of pottery and mine workers. It is necessary to convert Chinese dust measurements to respirable silica measurements in order to make results from the Chinese data comparable to other results in the literature. This article describes the development of conversion factors and estimates of historical respirable crystalline silica exposure for Chinese workers. Ambient total dust concentrations (n>17000) and crystalline silica concentrations (n=347) in bulk dust were first gathered from historical industrial hygiene records. Analysis of the silica content in historical bulk samples revealed no trend from 1950 up to the present. During 1988-1989, side-by-side airborne dust samples (n=143 pairs) were collected using nylon cyclones and traditional Chinese samplers in 20 metal mines and nine pottery factories in China. These data were used to establish conversion factors between respirable crystalline silica concentrations and Chinese total dust concentrations. Based on the analysis of the available evidence, conversion factors derived from the 1988-1989 sampling campaign are assumed to apply to other time periods in this paper. The conversion factors were estimated to be 0.0143 for iron/copper, 0.0355 for pottery factories, 0.0429 for tin mines, and 0.0861 for tungsten mines. Conversion factors for individual facilities within each industry were also calculated. Analysis of variance revealed that mean conversion factors are significantly different among facilities within the iron/copper industry and within the pottery industry. The relative merits of using facility-specific conversion factors, industry-wide conversion factors, or a weighted average of the two are discussed. The exposure matrix of the historical Chinese total dust concentrations was multiplied by these conversion factors to obtain an exposure matrix of historical respirable crystalline silica concentrations.
authors.affiliation: National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, US Department of Health and Human Services, 1095 Willowdale Road, Morgantown, WV 26505, USA. zaz3@cdc.gov
authors.forename: Z
authors.initials: Z
authors.lastname: Zhuang
authors.forename: F J
authors.initials: FJ
authors.lastname: Hearl
authors.forename: J
authors.initials: J
authors.lastname: Odencrantz
authors.forename: W
authors.initials: W
authors.lastname: Chen
authors.forename: B T
authors.initials: BT
authors.lastname: Chen
authors.forename: J Q
authors.initials: JQ
authors.lastname: Chen
authors.forename: M A
authors.initials: MA
authors.lastname: McCawley
authors.forename: P
authors.initials: P
authors.lastname: Gao
authors.forename: S C
authors.initials: SC
authors.lastname: Soderholm
mesh_terms: D000395:Air Pollutants, Occupational / Q000032:analysis*; D002516:Ceramics; D002681:China; D003300:Copper; D004391:Dust / Q000032:analysis*; D006801:Humans; D008906:Mining; D018401:Sample Size; D012680:Sensitivity and Specificity; D012822:Silicon Dioxide / Q000032:analysis*; D014414:Tungsten
chemical_list: D000395:Air Pollutants, Occupational; D004391:Dust; D012822:Silicon Dioxide; D003300:Copper; D014414:Tungsten