Inherited bleeding disorders in dermatologic surgery.
BACKGROUND
A patient referred for Mohs micrographic surgery of a basal cell carcinoma had a history of a congenital clotting factor IX deficiency requiring recombinant factor IX replacement.


OBJECTIVE
To examine the management and problems associated with cutaneous surgery in patients with inherited clotting factor deficiencies.


METHODS
Case report and review of the medical literature.


RESULTS
Reconstructive options must be carefully chosen to minimize bleeding in patients with clotting factor deficiencies. Preoperative consultation with a hematologist and coagulation factor replacement both before and after cutaneous surgery prevent excessive hemorrhage.


CONCLUSIONS
Meticulous attention to hemostasis, careful preoperative assessment, and postoperative follow-up minimize complications in patients with known coagulation deficiencies who require cutaneous surgery.
Peterson
S R
SR
Department of Dermatology, University of Texas Health Science Center at Houston, 77030, USA. sraypeterson@hotmail.com
Joseph
A K
AK
D000368:Aged; D002280:Basal Cell Carcinoma / Q000150:complications* / Q000601:surgery; D005164:Factor IX / Q000008:administration & dosage; D002836:Hemophilia B / Q000150:complications* / Q000628:therapy; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control; D006488:Hemostasis, Surgical; D006801:Humans; D008297:Male; D015580:Mohs Surgery; D009669:Nose Neoplasms / Q000150:complications* / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D016038:Skin Transplantation
D005164:Factor IX