The influence of selected bioadhesive polymers on physical-chemical properties of stomatological dressing.
Dressings made from polyvinyl alcohol (PAV) and Hydroxypropylmethylcellulose (HPMC) with the addition of glycerol (GLY) differ in adhesiveness and the time of wash out in water, both characteristics depended on polymer and GLY concentration. The research on the release speed which is applied in topical therapy of chlorhexidine digluconate antiseptic in biopharmaceutical model proved the existence of close to rectilinear relation between the amount of released substance and release time for selected formulations.
Pluta
J
J
Department of Dispensing Pharmacy, Wroclaw Medical University.
Karolewicz
B
B
D000268:Adhesiveness; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D003692:Delayed-Action Preparations / Q000008:administration & dosage*; D005990:Glycerol; D065347:Hypromellose Derivatives; D008422:Materials Testing; D008747:Methylcellulose / Q000031:analogs & derivatives*; D010511:Periodontal Dressings; D011108:Polymers; D011142:Polyvinyl Alcohol; D012212:Rheology
D000891:Anti-Infective Agents, Local; D003692:Delayed-Action Preparations; D011108:Polymers; D065347:Hypromellose Derivatives; D011142:Polyvinyl Alcohol; D008747:Methylcellulose; C010882:chlorhexidine gluconate; D005990:Glycerol; D002710:Chlorhexidine