title: Osteomyelitis caused by Paracoccidioides brasiliensis in a child from the metropolitan area of Rio de Janeiro.
abstract: The authors describe a case of paracoccidioidomycosis in a 7-year-old girl from the city of Rio de Janeiro who initially presented to her physician with a lesion in her calcaneous which was misdiagnosed and treated as bacterial osteomyelitis. Later, cutaneous manifestations, lymph node enlargement, and hepatosplenomegaly developed and biopsy of the skin and cervical lymph nodes showed the fungus which was also present in the sputum. It is emphasized that Paracoccidioides brasiliensis can be the cause of bone lesions in endemic areas of Latin America and that response to treatment with amphotercin B is good.
authors.affiliation: Hospital Universitário Clementino Fraga Filho, Serviço de Doenças Infecciosas e Parasitárias, University Federal do Rio de Janeiro, Brazil. susie@hucff.ufrj.br
authors.forename: S A
authors.initials: SA
authors.lastname: Nogueira
authors.forename: A L
authors.initials: AL
authors.lastname: Guedes
authors.forename: B
authors.initials: B
authors.lastname: Wanke
authors.forename: S
authors.initials: S
authors.lastname: Capella
authors.forename: K
authors.initials: K
authors.lastname: Rodrigues
authors.forename: T F
authors.initials: TF
authors.lastname: Abreu
authors.forename: J C
authors.initials: JC
authors.lastname: Morais
authors.forename: J S
authors.initials: JS
authors.lastname: Lambert
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001938:Brazil; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology*; D010228:Paracoccidioides / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B