The effects of light therapy on mini-mental state examination scores in demented patients.
BACKGROUND
Preliminary evidence suggests that demented patients may experience beneficial effects of light therapy. The authors tested whether bright light therapy (BLT) is capable of improving cognitive functions in patients with Alzheimer-type dementia (AD) or vascular dementia (VD).


METHODS
Twenty-three patients with AD or VD were randomly assigned to either evening BLT or dim light therapy (DLT). Effects of light therapy on cognitive functions were assessed before and after light therapy using Mini-Mental State Examination (MMSE) scores. Body temperature rhythm (BTR) was additionally recorded pre- and posttreatment.


RESULTS
Irrespective of their diagnosis, patients treated with BLT (p =.0012) but not with DLT (p =.73) showed a statistically significant increase in MMSE total scores after light therapy. Evening BLT simultaneously induced a significant phase delay of 56 min on BTR (p =.025).


CONCLUSIONS
Our preliminary results suggest that short-term evening BLT may exert beneficial effects on cognitive functioning in patients with dementia.
Graf
A
A
Department of General Psychiatry, University of Vienna, Vienna, Austria.
Wallner
C
C
Schubert
V
V
Willeit
M
M
Wlk
W
W
Fischer
P
P
Kasper
S
S
Neumeister
A
A
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000628:therapy*; D001831:Body Temperature / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis*; D015140:Dementia, Vascular / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010789:Phototherapy