title: Migraine MLT-down: an unusual presentation of migraine in patients with aspartame-triggered headaches.
abstract: Aspartame, an artificial sweetener added to many foods and beverages, may trigger headaches in susceptible individuals. We report two patients with aspartame-triggered attacks in whom the use of an aspartame-containing acute medication (Maxalt-MLT) worsened an ongoing attack of migraine.
authors.affiliation: The Headache Institute, St. Lukes-Roosevelt Hospital Center, 1000 Tenth Avenue, Suite 1C10, New York, NY 10019, USA.
authors.forename: L C
authors.initials: LC
authors.lastname: Newman
authors.forename: R B
authors.initials: RB
authors.lastname: Lipton
mesh_terms: D000293:Adolescent; D000328:Adult; D001218:Aspartame / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000139:chemically induced / Q000188:drug therapy* / Q000503:physiopathology*; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use; D013549:Sweetening Agents / Q000009:adverse effects* / Q000627:therapeutic use; D014230:Triazoles / Q000009:adverse effects* / Q000627:therapeutic use; D014363:Tryptamines
chemical_list: D017366:Serotonin Receptor Agonists; D013549:Sweetening Agents; D014230:Triazoles; D014363:Tryptamines; C093622:rizatriptan; D001218:Aspartame