[The sleep apnea syndrome in hypophyseal disorders with the exception of acromegaly].
The aim of the study was to ascertain the occurrence of the sleep apnoea syndrome (SAS) in patients after pituitary afunctional adenoma operation or in patients with other affection in sella turcica region except acromegaly patients. Eighty-one patients were addressed. Sixteen patients (eight men, eight women) underwent the examination; the rest of them had no interest to be explored. Afunctional pituitary adenoma was diagnosed in twelve patients, afunctional pituitary adenoma and subsequently optic glioma in one patient, craniopharyngioma in one patient, prolactinoma in one patient and undifferentiated cystic pituitary tumour in one patient. Neurological examination was done in all patients (standardized sleep questionnaire was included). SAS was quantified using PolyMESAM. Severity of SAS were set up from the value of M index (M = ODI.delta saturation; ODI--oxygen desaturation index). Mild SAS: 40 < M < 100; middle SAS: 100 < M < 210; severe SAS: M > 210. SAS was diagnosed in 13 patients: mild SAS in three of them (average value of M index: 81.0 +/- 12.7), moderate SAS in seven patients (average value of M index: 129.0 +/- 18.7) and severe SAS in three patients (average value of M index: 790.0 +/- 563.0). Therapy by continuous positive airway pressure (CPAP) was recommended in six patients. Five of them continue in using of CPAP--four patients with good compliance. The occurrence of SAS was 16.05% in measured group, higher than in normal population.
Pretl
M
M
Neurologická klinika, 1. lékarské fakulty Univerzity Karlovy a Vseobecné fakultní nemocnice v Praze, Katerinská 30, 120 00 Praha 2-Nové Mĕsto, Czech Republic. mpretl@lf1.cuni.cz
Weiss
V
V
Sonka
K
K
Marek
J
J
Dostálová
S
S
Rambousek
P
P
Homolka
J
J
D000172:Acromegaly; D000236:Adenoma / Q000150:complications / Q000601:surgery; D003397:Craniopharyngioma / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications* / Q000601:surgery; D017286:Polysomnography; D015175:Prolactinoma / Q000150:complications; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000175:diagnosis