title: Radioactive gold-198 seeds for the treatment of squamous cell carcinoma in the eyelid of a cat.
abstract: A 19-year-old, speyed, domestic short-hair cat was presented with an eyelid tumour of 3 months duration. Ophthalmic examination revealed a large, raised, ulcerated and bleeding mass affecting the left lower eyelid. The mass was 12 mm x 10 mm in size, extended to the medial canthus and had eroded 10 mm of eyelid margin. Mandibular lymph nodes were not palpably enlarged. A diagnosis of squamous cell carcinoma was confirmed by histologic examination. Due to involvement of more than half the lower eyelid, it was decided that treatment with radioactive gold-198 seeds was appropriate. Nine radioactive gold-198 seeds were implanted, delivering a minimum tumour dose of 65 Gy. Three weeks postoperatively the mass had resolved, with only a small scab remaining. After a further 3 weeks, there was no evidence of the eyelid tumour. Although approximately 7 mm of eyelid margin was absent, this did not cause any clinical signs other than mild conjunctivitis. There was no evidence of the tumour 10 months postoperatively, when the cat was euthanased for unrelated disease.
authors.affiliation: Animal Eye Care, East Malvern, Victoria. chloeh@medeserv.com.au
authors.forename: C
authors.initials: C
authors.lastname: Hardman
authors.forename: R
authors.initials: R
authors.lastname: Stanley
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001918:Brachytherapy / Q000379:methods / Q000662:veterinary; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy / Q000662:veterinary*; D002371:Cat Diseases / Q000473:pathology / Q000532:radiotherapy*; D002415:Cats; D005142:Eyelid Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000662:veterinary*; D005260:Female; D006048:Gold Colloid, Radioactive / Q000627:therapeutic use*; D012449:Safety; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D006048:Gold Colloid, Radioactive