Quantification of coronary artery calcium using multidetector CT and a retrospective ECG-gating reconstruction algorithm.
OBJECTIVE
The purpose of our study was to evaluate the quality of and motion artifacts on multidetector CT scans and to compare the results with those of and on electron beam CT scans for the assessment of coronary calcium scores.


METHODS
First, 20 volunteers were scanned using multidetector CT. We compared the signal-to-noise ratio in the heart, motion artifacts at the heart border, and the highest CT values in the regions of the coronary arteries using single-sector and multisector reconstruction algorithms. Next, 60 patients with coronary calcified deposits underwent both multidetector CT and electron beam CT. We compared coronary calcium scores determined with multidetector CT using the two algorithms (thresholds of 90 and 130 H) with those determined using electron beam CT.


RESULTS
The signal-to-noise ratio was higher and motion artifacts were reduced when we used the multisector algorithm. The highest CT value in the region of the coronary arteries exceeded 90 H in one of 55 arteries on the multisector algorithm images and 17 of 55 arteries on single-sector algorithm images (chi-square test, p < 0.01). In coronary calcium scoring, correlation coefficients ranged from 0.920 to 0.992 (Pearson's product moment) and from 0.932 to 0.969 (Spearman's rank correlation coefficient).


CONCLUSIONS
Multidetector CT with a retrospective ECG-gating algorithm (multisector reconstruction) produced cardiac images with fewer motion artifacts and showed a high correlation with coronary calcium scores determined using electron beam CT. Therefore, multidetector CT is a potential tool for coronary calcium scoring.
Horiguchi
J
J
Department of Radiology, Hiroshima University School of Medicine, 1-2-3, Kasumi-cho, Minami-ku, Hiroshima, 734-8551, Japan.
Nakanishi
T
T
Ito
K
K
D000328:Adult; D000465:Algorithms; D002114:Calcinosis / Q000000981:diagnostic imaging; D002118:Calcium / Q000032:analysis*; D003327:Coronary Disease / Q000000981:diagnostic imaging; D003331:Coronary Vessels / Q000737:chemistry*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
D002118:Calcium