Mild conversion of alcohols to alkyl halides using halide-based ionic liquids at room temperature.
[reaction--see text] Alcohols were efficiently converted to alkyl halides using 1-n-butyl-3-methylylimidazolium halides (ionic liquids) in the presence of Brønsted acids at room temperature. The alkyl halide products were easily isolated from the reaction mixture via simple decantation or extraction, and the 1-n-butyl-3-methylimidazolium cation could be recycled for further uses.
Ren
R X
RX
Max Tishler Laboratory of Organic Chemistry, Department of Chemistry, Wesleyan University, Middletown, Connecticut 06459, USA. rren@wesleyan.edu
Wu
J X
JX