[Apoptosis induced by ionizing radiation in TCC cell lines, EJ and BIU-87].
OBJECTIVE
To study the effect of ionizing radiation on the living status of TCC cell lines, EJ and BIU-87.


METHODS
Different doses of X-ray were used on cell lines, EJ and BIU-87, and the cells were observed microscopically by fluorescent staining(EB and AO).


RESULTS
The number of normal living cells declined and apoptotic as well as necrotic cells elevated with increase of radiation doses except for doses equal to or below 100 cGY, Apoptotic and necrotic cells increased as postradiation time delayed.


CONCLUSIONS
The ionizing radiation may induce TCC apoptosis and necrosis.
Yang
B
B
Institute of Urology, Beijing Medical University, Beijing 100034.
Yu
L
L
Ding
Y
Y
D017209:Apoptosis / Q000528:radiation effects*; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D010315:Particle Accelerators; D014407:Tumor Cells, Cultured; D001749:Urinary Bladder Neoplasms / Q000473:pathology*