title: Macromolecular complexes: SMN--the master assembler.
abstract: Recent studies indicate that the protein affected in spinal muscular atrophy, SMN, plays a role in the assembly of a number of macromolecular complexes that function in the nucleus, interacting with its partner proteins via their arginine- and glycine-rich domains.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Georgia, Life Sciences Building, Athens, Georgia 30602, USA. mterns@bmb.uga.edu
authors.forename: M P
authors.initials: MP
authors.lastname: Terns
authors.forename: R M
authors.initials: RM
authors.lastname: Terns
mesh_terms: D020541:Coiled Bodies / Q000378:metabolism; D017362:Cyclic AMP Response Element-Binding Protein; D009134:Muscular Atrophy, Spinal / Q000209:etiology*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011485:Protein Binding; D012326:RNA Splicing; D016601:RNA-Binding Proteins; D017411:Ribonucleoproteins, Small Nuclear / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism; D055532:SMN Complex Proteins; D017381:Spliceosomes / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D017362:Cyclic AMP Response Element-Binding Protein; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins; D017411:Ribonucleoproteins, Small Nuclear; D055532:SMN Complex Proteins