[Spatial tuning curve recording in inferior colliculus during electrical stimulation of the cochlea].
OBJECTIVE
To explore the electrical activity mechanism of auditory center to intracochlear electrical stimulation and provide physiological foundation for spatial encoding of electrical stimulation in multiple channel cochlear implant.


METHODS
The spatial tuning curves(STC) in the inferior colliculus(IC) to monopolar electrical stimulation, bipolar electrical stimulation and tone stimulation in cats were composed by using the single unit and the multi-units cluster recording method.


RESULTS
The bipolar electrical stimulation excited the response in the specific region in IC, which was similar to the response induced by tone stimulation. The monopolar electrical stimulation excited an extensive response and could not provide the spatial encoding.


CONCLUSIONS
Using the bipolar electrical stimulation, the stimulation region is the key point for improving the spatial encoding. The physiological results of spatial encoding of monopolar electrical stimulation contradicted the psychophysical conclusion and the clinical effect of CI patients. The explanation to this needs further studies.
Pan
T
T
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730.
Cao
K
K
Wang
Z
Z
D000818:Animals; D001301:Audiometry, Pure-Tone; D002415:Cats; D003051:Cochlea / Q000502:physiology*; D003054:Cochlear Implants; D004558:Electric Stimulation / Q000379:methods; D007245:Inferior Colliculi / Q000502:physiology*