QSAR correlations of the algistatic activity of 5-amino-1-aryl-1H-tetrazoles.
The algistatic activity of 20 substituted 5-amino-1-aryl-1H-tetrazoles was correlated with the second order Kier and Hall index, the XY shadow on the XY rectangle and the total hybridization component of the molecular dipole by the CODESSA program in a three parameter equation with r2 = 0.9330.
Katritzky
A R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, P.O. Box 11720, Gainesville, FL 32611-7200, USA.
Jain
R
R
Petrukhin
R
R
Denisenko
S
S
Schelenz
T
T
D056890:Eukaryota / Q000187:drug effects*; D016014:Linear Models; D021281:Quantitative Structure-Activity Relationship; D013777:Tetrazoles / Q000737:chemistry / Q000494:pharmacology*
D013777:Tetrazoles