title: Moving to the routine management of pre symptomatic lung cancer.
abstract: Lung cancer is the world's leading cause of cancer death. Since progress in the treatment of this cancer has been exceedingly slow, the upswing in tobacco consumption in many sectors becomes even more tragic. One area for cautious optimism is the recent pilot reports of improved early lung cancer detection using new spiral CT techniques from institutions in Japan and New York. The prospect of improved early detection in a major cancer raises a number of public health concerns and highlights the importance of critical validation of this proposed new tool. From experience with early detection-based management of other cancers, it is evident that the entire process of detection, case validation, intervention, monitoring and public education needs to be carefully developed. The International Association for the Study of Lung Cancer has worked with the National Cancer Institute over the last decade to nurture interest and expertise in conducting population-based management of early lung cancer. A distillation of this process up to the current time is reviewed in this manuscript.
authors.affiliation: Intervention Section, Center for Cancer Research, NCI, NIH, Bethesda, MD 20850, USA. mulshinej@bprb.nci.nih.gov
authors.forename: J L
authors.initials: JL
authors.lastname: Mulshine
authors.forename: S
authors.initials: S
authors.lastname: Hong
authors.forename: A
authors.initials: A
authors.lastname: Martínez
authors.forename: J
authors.initials: J
authors.lastname: Tauler
authors.forename: I
authors.initials: I
authors.lastname: Avis
authors.forename: M S
authors.initials: MS
authors.lastname: Tockman
authors.forename: L M
authors.initials: LM
authors.lastname: De Luca
authors.forename: M E
authors.initials: ME
authors.lastname: Placke
authors.forename: F
authors.initials: F
authors.lastname: Cuttitta
mesh_terms: D019468:Disease Management; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D008403:Mass Screening; D009367:Neoplasm Staging; D010353:Patient Education as Topic; D011634:Public Health; D014057:Tomography, X-Ray Computed