Glucose sensing based on interdigitated array microelectrode.
A micro glucose sensor consisting of an interdigitated array gold microelectrode was developed. The interdigitated array structure, which has 10 microns band width and 10 microns band gap, was fabricated in a small region (2.5 x 5 mm2) on a quartz substrate. Glucose oxidase was chemically fixed onto the electrode surface through self-assembled monolayer of 11-mercaptoundecanoic acid; ferroceneacetic acid was used as electron mediator. Electrochemical properties of the glucose oxidase-immobilized microelectrode were investigated by cyclic voltammogram measurements. Results confirmed that the reductive ferroceneacetic acid generated at counter electrode diffuses through a narrow band gap (10 microns) and can reach the working electrode surface.
Jin
P
P
Department of Automation Measurement and Control Engineering, Harbin Institute of Technology, No. 92 West Dazhi Street, Harbin 150001, P.R. China.
Yamaguchi
A
A
Oi
F A
FA
Matsuo
S
S
Tan
J
J
Misawa
H
H
D019342:Acetic Acid / Q000737:chemistry; D025802:Electric Capacitance; D004566:Electrodes; D005296:Ferrous Compounds / Q000737:chemistry; D005947:Glucose / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D005949:Glucose Oxidase / Q000737:chemistry; D006046:Gold; D000075163:Metallocenes; D010100:Oxygen / Q000378:metabolism; D055672:Static Electricity; D013997:Time Factors
D005296:Ferrous Compounds; D000075163:Metallocenes; D006046:Gold; D005949:Glucose Oxidase; D005947:Glucose; D019342:Acetic Acid; D010100:Oxygen; C004998:ferrocene