title: Subcortical dementia associated with striking enlargement of the Virchow-Robin spaces and transneural degeneration of the left mammillo-thalamic tract.
abstract: We report a case of subcortical dementia in a 68-year-old woman. MR examination of the patient's brain revealed two types of alterations as a possible cause of the dementia, both anomalous in respect of their entity and incidence: the first was a striking enlargement of the Virchow-Robin spaces, and the second an anterograde transneural degeneration of the left mammillo-thalamic tract and mammillary body secondary to a lacunar infarction of the ipsilateral anterior thalamus.
authors.affiliation: Department of Neuroradiology, Neurological Institute Fondazione C. Mondino, Pavia, Italy. uggetti@mondino.it
authors.forename: C
authors.initials: C
authors.lastname: Uggetti
authors.forename: M G
authors.initials: MG
authors.lastname: Egitto
authors.forename: A
authors.initials: A
authors.lastname: Pichiecchio
authors.forename: E
authors.initials: E
authors.lastname: Sinforiani
authors.forename: M S
authors.initials: MS
authors.lastname: Bevilacqua
authors.forename: A
authors.initials: A
authors.lastname: Cavallini
authors.forename: G
authors.initials: G
authors.lastname: Micieli
mesh_terms: D000368:Aged; D020643:Anterior Thalamic Nuclei / Q000473:pathology*; D015140:Dementia, Vascular / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008326:Mammillary Bodies / Q000473:pathology*; D009410:Nerve Degeneration / Q000473:pathology*