title: Mortality and morbidity in reoperation comparing to first intervention in coronary revascularization.
abstract: BACKGROUND
  Coronary artery reoperation represents about 20% of coronary artery operations. In this study we compared mortality and morbidity of first intervention and redo operation.
  
  
  METHODS
  
  
  
  METHODS
  a retrospective study.
  
  
  METHODS
  patients who underwent coronary artery reoperations in a University Cardiac Surgery Division in 1991-1994.
  
  
  METHODS
  our clinical survey was composed of two groups: group A included 44 consecutive patients (mean age 60+/-7 years, males/females=41/3) who underwent a coronary artery reoperation in the years 1991-1994 at the University Cardiac Surgery Division of Turin; group B included 344 patients (mean age 58+/-8 years, males/females=289/55) randomly selected among those who underwent a first coronary operation in the above indicated period of time and centre. All patients had angina pectoris refractory to maximal medical therapy.
  
  
  METHODS
  all patients underwent a coronary artery operation in extracorporeal circulation (ECC), under mild hypothermia (30-32 degrees C), during a single aortic clamp period, with antegrade cold crystalloid cardioplegia (St. Thomas).
  
  
  METHODS
  comparison of clinical preoperative features, risk factors and postoperative mortality and morbidity between the two groups.
  
  
  RESULTS
  In reoperated patients we observed a greater mean akinesis score (p<0.001) and severe left ventricular dysfunction presence (p=0.014). Reoperation mortality was 11.4% against first operation mortality of 3.2% (p=0.03). Female gender (p=0.03), intra-aortic balloon counterpulsation need (p=0.002), adrenaline use (p=0.004) and low cardiac output syndrome (p=0.007) were all perioperative risk factors in group A.
  
  
  CONCLUSIONS
  Coronary artery reoperation involves a higher mortality and morbidity compared to the first operation, especially related to the reduced left ventricular function which characterises the population that undergoes reoperation.
authors.affiliation: Cardiology Division, University of Turin, Molinette Hospital, Turin, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Merlo
authors.forename: E
authors.initials: E
authors.lastname: Aidala
authors.forename: E
authors.initials: E
authors.lastname: La Scala
authors.forename: L
authors.initials: L
authors.lastname: Carrieri
authors.forename: I
authors.initials: I
authors.lastname: Paglia
authors.forename: S
authors.initials: S
authors.lastname: Drago
authors.forename: A
authors.initials: A
authors.lastname: Gagnor
authors.forename: S
authors.initials: S
authors.lastname: Pansini
authors.forename: S
authors.initials: S
authors.lastname: Bergerone
authors.forename: M
authors.initials: M
authors.lastname: Di Summa
authors.forename: G
authors.initials: G
authors.lastname: Trevi
mesh_terms: D001026:Coronary Artery Bypass / Q000401:mortality*; D005112:Extracorporeal Circulation; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012086:Reoperation / Q000401:mortality*; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D018487:Ventricular Dysfunction, Left