Cystosarcoma phyllodes of the prostate with rhabdomyoblastic differentiation.
A 36-year-old man presented with recurrent urinary obstruction and an enlarged, partially cystic prostate tumour on ultrasonography. Microscopically, the tumour was composed of cystically dilated ducts with leaf-like stromal projections in the lumen. A portion of the stroma was very cellular with atypia and a high mitotic rate. In addition, there was a small focus with well differentiated rhabdomyoblasts. This case is the second description of a cystosarcoma phyllodes of the prostate with rhabdomyoblasts differentiation. With radical surgery and chemotherapy only partial remission could be obtained.
De Raeve
H
H
Department of Surgical Pathology, University Hospital Antwerp, Edegem, Belgium.
Jeuris
W
W
Wyndaele
J J
JJ
Van Marck
E
E
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008297:Male; D009364:Neoplasm Recurrence, Local; D003557:Phyllodes Tumor / Q000473:pathology* / Q000628:therapy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000628:therapy; D012208:Rhabdomyosarcoma / Q000473:pathology* / Q000628:therapy; D017154:Stromal Cells / Q000473:pathology
D004317:Doxorubicin; D007069:Ifosfamide