tRNAs in the spotlight during protein biosynthesis.
High resolution crystal structures of the ribosome provide fascinating insights into perhaps the most sophisticated machine of a cell. Yet, this translational apparatus must have developed from a much more primitive structure. Throughout the evolution of this apparatus, tRNAs have been, and still are, key players in the translation process.
Brosius
J
J
Institute of Experimental Pathology/Molecular Neurobiology, ZMBE, University of Münster, Von-Esmarch-Str. 56, Münster, Germany. RNA.world@uni-muenster.de
D000595:Amino Acid Sequence; D019143:Evolution, Molecular; D008956:Models, Chemical; D008958:Models, Molecular; D010452:Peptide Biosynthesis; D011387:Prokaryotic Cells / Q000378:metabolism; D014176:Protein Biosynthesis / Q000235:genetics*; D017434:Protein Structure, Tertiary; D012333:RNA, Messenger / Q000378:metabolism; D012335:RNA, Ribosomal / Q000096:biosynthesis* / Q000235:genetics; D012343:RNA, Transfer / Q000737:chemistry / Q000378:metabolism*; D012269:Ribosomal Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012270:Ribosomes / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D012333:RNA, Messenger; D012335:RNA, Ribosomal; D012269:Ribosomal Proteins; D012343:RNA, Transfer