title: Huge response to letrozole in inoperable T4 breast cancer: a case report.
abstract: A 73 years-old woman presented with locally advanced breast cancer (cT4b cN1 M0, stage IIIB) and atrial flutter. Because of the arrhythmia, chemotherapy or tamoxifen, although malignancy was hormone-sensitive, were discarded. Letrozole was started. Two months later, the breast nodule and skin ulceration cleared up. Surgery was performed. Nowadays, 24 months later, patient does fine, continuing letrozole as adjuvant treatment.
authors.affiliation: Breast Cancer Unit, University Campus Bio-Medico, Rome, Italy. sdicosimo@hotmail.com
authors.forename: S
authors.initials: S
authors.lastname: Di Cosimo
authors.forename: V
authors.initials: V
authors.lastname: Altomare
authors.forename: G
authors.initials: G
authors.lastname: Ferretti
authors.forename: G
authors.initials: G
authors.lastname: Gravante
authors.forename: C
authors.initials: C
authors.lastname: Rabitti
authors.forename: F
authors.initials: F
authors.lastname: Rea
authors.forename: A
authors.initials: A
authors.lastname: Arullani
authors.forename: M
authors.initials: M
authors.lastname: D'Aprile
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000077289:Letrozole; D009570:Nitriles / Q000627:therapeutic use*; D012074:Remission Induction; D014230:Triazoles / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D009570:Nitriles; D014230:Triazoles; D000077289:Letrozole