Congenital malaria in a hyperendemic area: a revisit.
Screening of 104 mother-baby pairs for P. falciparum malaria revealed that 29% of mothers from low socio-economic group and 11% of their babies had malaria parasitaemia. The corresponding figures for middle and high socio-economic groups were 15% and 7%, respectively. The parasite densities in the babies were not proportional to maternal load and were generally low, although higher in the low socio-economic group. Maternal pyrimethamine prophylaxis did not appear to protect babies from parasitisation and there was no demonstrable beneficial effect on the babies' birtth-weights.
Olowu
J A
JA
Department of Paediatrics, College of Medicine, University College Hospital, Ibadan, Nigeria.
Sowunmi
A
A
Abohweyere
A E
AE
D000962:Antimalarials / Q000627:therapeutic use; D001724:Birth Weight; D004522:Educational Status; D019353:Endemic Diseases / Q000706:statistics & numerical data*; D005260:Female; D006771:Hospitals, Maternity / Q000706:statistics & numerical data; D006785:Hospitals, University / Q000706:statistics & numerical data; D006786:Hospitals, Urban / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control / Q000706:statistics & numerical data; D016778:Malaria, Falciparum / Q000151:congenital* / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D008297:Male; D008403:Mass Screening; D009035:Mothers / Q000193:education; D020380:Needs Assessment; D010353:Patient Education as Topic; D011159:Population Surveillance; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000453:epidemiology* / Q000517:prevention & control; D015995:Prevalence; D011446:Prospective Studies; D011739:Pyrimethamine / Q000627:therapeutic use; D012307:Risk Factors; D012959:Socioeconomic Factors
D000962:Antimalarials; D011739:Pyrimethamine