Evaluation of the efficacy of two leishmanins in asymptomatic dogs.
There are few studies in dogs concerning leishmanin skin test. We evaluated and compared the efficacy of two leishmanin preparations for the detection of dog Leishmania cellular-mediated immunity. Clinically healthy dogs living in an endemic area were studied. A leishmanin preparation 1 (3 x 10(8) promastigotes/ml) was superior to a leishmanin preparation 2 (5 x 10(6) promastigotes/ml), measured as the percentage of positive reactions and the diameter of the induced induration. The leishmanin skin test is a valuable tool, although the results show that the degree of response, as it has been shown in human beings, depends on the preparation used.
Solano-Gallego
L
L
Facultat de Veterinària, Departament de Farmacologia i de Terapèutica, Universitat Autònoma de Barcelona, Edifici V, Bellaterra, E-08193 Barcelona, Spain. lsolano@quiro.uab.es
Llull
J
J
Arboix
M
M
Ferrer
L
L
Alberola
J
J
D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D004283:Dog Diseases / Q000276:immunology* / Q000469:parasitology; D004285:Dogs; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000662:veterinary; D007111:Immunity, Cellular; D007891:Leishmania; D007896:Leishmaniasis / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D012680:Sensitivity and Specificity; D012867:Skin / Q000276:immunology; D012882:Skin Tests / Q000662:veterinary
D000953:Antigens, Protozoan; C032127:leishmanin