Detection of circulating CEA molecules in human sera and leukopheresis of peripheral blood stem cells with E. coli expressed bispecific CEAScFv-streptavidin fusion protein-based immuno-PCR technique.
In this study, a method called bispecific CEAScFv-streptavidin fusion protein-based immuno-PCR technique will be tested experimentally. The application of the bispecific fusion protein-based immuno-PCR technique has the significant advantage that it can be readily applied in the clinical setting, as well as tested as a potential screening tool in high-risk populations of certain types of cancer.
Ren
J
J
Center of Clinical Oncology, Xijing Hospital, The Fourth Military Medical University, Xi'an, China. renjun@fmmu.edu.cn
Ge
L
L
Li
Y
Y
Bai
J
J
Liu
W C
WC
Si
X M
XM
D002272:Carcinoembryonic Antigen / Q000097:blood*; D004926:Escherichia coli / Q000235:genetics*; D006801:Humans; D007937:Leukapheresis; D016133:Polymerase Chain Reaction / Q000379:methods*; D011993:Recombinant Fusion Proteins / Q000235:genetics; D013234:Stem Cells / Q000276:immunology*
D002272:Carcinoembryonic Antigen; D011993:Recombinant Fusion Proteins