title: Ruthenium-catalyzed olefin metathesis in ionic liquids.
abstract: [reaction--see text] Ionic liquid 1-butyl-3-methylimidazoliumhexafluorophosphate ([bmim]PF(6)) is described as an effective medium for ring-closing metathesis (RCM) using Grubbs catalysts. When [bmim]PF(6) was used as solvent, the RCM showed high conversions and a broad substrate tolerance. [bmim]PF(6) and the ruthenium catalyst were recycled after extraction of the product in the organic phase for at least three cycles.
authors.affiliation: Lead Discovery Unit, N.V. Organon, P.O. Box 20, 5340 BH Oss, The Netherlands. rogier.buijsman@organon.com
authors.forename: R C
authors.initials: RC
authors.lastname: Buijsman
authors.forename: E
authors.initials: E
authors.lastname: van Vuuren
authors.forename: J G
authors.initials: JG
authors.lastname: Sterrenburg