Incidence of human immunodeficiency virus among male-to-female transgendered persons in San Francisco.
OBJECTIVE
To estimate HIV incidence among male-to-female transgendered persons (MtF transgendered persons) who repeatedly tested for HIV antibodies at public San Francisco counseling and testing sites between July 1997 and June 2000.


METHODS
HIV seroconversions were identified and person-time of observation were estimated using the date and result of the current test and the self-reported date and result of the previous test. Factors independently associated with HIV seroconversion were determined using multivariable proportional hazard analysis.


RESULTS
HIV incidence was 7.8 per 100 person-years (95% confidence intervals [CI], 4.6-12.3) based on 13 seroconversions among 155 repeat testers with 167.7 person-years of observation. African-American race/ethnicity (adjusted relative hazard ratio [HR], 5.0; 95% CI, 1.5-16.2) and unprotected receptive anal intercourse (HR, 3.9; 95% CI, 1.2-13.1) were independent predictors of HIV seroconversion.


CONCLUSIONS
HIV is currently spreading at an extremely high rate among MtF transgendered persons in San Francisco, especially those who are African Americans.
Kellogg
T A
TA
Department of Public Health, San Francisco, California, USA. Tim_Kellogg@dph.sf.ca.us
Clements-Nolle
K
K
Dilley
J
J
Katz
M H
MH
McFarland
W
W
D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012495:San Francisco / Q000453:epidemiology; D014189:Transsexualism
D015483:HIV Antibodies