title: A novel use of Grubbs' carbene. Application to the catalytic deprotection of tertiary allylamines.
abstract: [reaction--see text] The first examples accounting for the catalytic deprotection of allylic amines by using reagents different from palladium catalysts have been achieved via Grubbs' carbene-mediated reaction. The current mechanistic hypothesis invokes a nitrogen-assisted ruthenium-catalyzed isomerization, followed by hydrolysis of the enamine intermediate. We believe that an unprecedented mode of ring opening of the ruthenacyclobutane was involved.
authors.affiliation: Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040-Madrid, Spain. alcaideb@quim.ucm.es
authors.forename: B
authors.initials: B
authors.lastname: Alcaide
authors.forename: P
authors.initials: P
authors.lastname: Almendros
authors.forename: J M
authors.initials: JM
authors.lastname: Alonso
authors.forename: M F
authors.initials: MF
authors.lastname: Aly