title: Langerhans cell histiocytosis in a child while in remission for acute lymphocytic leukemia.
abstract: The occurrence of Langerhans cell histiocytosis (LCH) and malignancy in the same patient is rare. When LCH occurs concomitantly with acute leukemia, distinct temporal patterns often exist; acute myelogenous leukemia (AML) typically succeeds LCH, whereas acute lymphocytic leukemia (ALL) usually precedes it. We report a case of LCH developing in a child while in remission for ALL. Unique features of this case include the disseminated nature of the LCH and the death of the patient from LCH rather than ALL.
authors.affiliation: Department of Dermatology, The University Texas Medical Branch at Galveston, 77555-0783, USA.
authors.forename: L R
authors.initials: LR
authors.lastname: Chiles
authors.forename: M M
authors.initials: MM
authors.lastname: Christian
authors.forename: D K
authors.initials: DK
authors.lastname: McCoy
authors.forename: H K
authors.initials: HK
authors.lastname: Hawkins
authors.forename: A H
authors.initials: AH
authors.lastname: Yen
authors.forename: S S
authors.initials: SS
authors.lastname: Raimer
mesh_terms: D001415:Back; D002675:Child, Preschool; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D012871:Skin Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology