Distribution of rotavirus G and P types in north and south Indian children with acute diarrhoea in 1998-99.
VP7 and VP4 genotypes of 82 rotavirus strains from children with acute diarrhoea during November 1998-January 1999, in 4 Indian towns, were determined by reverse-transcription PCR. Overall, 68/82 (83%) could be VP7- and 52/82 (63%) VP4-typed. Geographical differences in rotavirus circulation have implications for future vaccination strategies.
Kang
G
G
Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632004, India. gkang@cmcvellore.ac.in
Raman
T
T
Green
J
J
Gallimore
C I
CI
Brown
D W
DW
D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology; D004797:Enzyme-Linked Immunosorbent Assay; D005838:Genotype; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D016133:Polymerase Chain Reaction / Q000379:methods; D012401:Rotavirus / Q000145:classification* / Q000235:genetics; D012400:Rotavirus Infections / Q000453:epidemiology*