title: [Is visual assessment of MRI adequate in the investigation of patients with temporal lobe epilepsy? Evaluation of the diagnostic accuracy of the visual assessment of MRI in mesial temporal sclerosis].
abstract: BACKGROUND
  Is visual assessment of MRI adequate in patients with temporal lobe epilepsy? Visual versus quantitative MRI assessment of mesial temporal sclerosis (hippocampal gliosis (HG) and hippocampal atrophy (HA)).
  
  
  METHODS
  The MRIs of 25 patients with temporal lobe epilepsy were assessed visually by three radiologists with different levels of neuroradiological MRI experience (expert, trained, and inexperienced). Diagnosis obtained earlier by T2-relaxometry and volume measurements were considered to be the gold standard.
  
  
  RESULTS
  The diagnostic accuracy of visual assessment was high for unilateral HA, but low for bilateral HA and unilateral and bilateral HG, and it was not better for the expert eye than for the inexperienced. Interobserver agreement on the visual diagnosis of HG and HA (Cohen's Kappa coefficient): 0.49 (HG) and 0.84 (HA). Intraobserver reliability for the expert/trained/inexperienced observer for visual diagnosis (Kappa): 0.83/0.64/0.47 (HG) and 0.88/0.69/0.73 (HA).
  
  
  CONCLUSIONS
  Reproducibility and diagnostic accuracy of visual assessment varied unacceptably from the quantitative MRI-based diagnosis. Quantitative measurements are recommended in patients suspected of MTS.
authors.affiliation: Arhus Universitetshospital, Skejby Sygehus, MR-centret.
authors.forename: J S
authors.initials: JS
authors.lastname: Sørensen
authors.forename: F T
authors.initials: FT
authors.lastname: Jensen
authors.forename: P B
authors.initials: PB
authors.lastname: Andersen
authors.forename: M S
authors.initials: MS
authors.lastname: Nielsen
authors.forename: B
authors.initials: B
authors.lastname: Pedersen
authors.forename: T
authors.initials: T
authors.lastname: Christensen
mesh_terms: D001284:Atrophy; D002983:Clinical Competence; D004833:Epilepsy, Temporal Lobe / Q000473:pathology*; D005911:Gliosis; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods / Q000592:standards*; D015588:Observer Variation; D012598:Sclerosis; D013702:Temporal Lobe / Q000473:pathology*