title: Surgery for aortic coarctation: a 30 years experience.
abstract: OBJECTIVE
  A retrospective study to review the experience of a single center with surgery for aortic coarctation over a period of 30 years (1970-1999).
  
  
  METHODS
  Criteria for inclusion: (a) aortic coarctation, isolated or associated with congenital heart defect; (b) surgery between 1970 and 1999. Data recorded: (1) date of surgery; (2) age at surgery; (3) associated lesions; (4) surgical technique; (5) simultaneous surgical procedures; (6) early and late surgical results in term of: (a) deaths; (b) need for reoperation because of re-coarctation or other cardiac lesion; (c) residual/recurrent pressure gradient, evaluated at cuff/Doppler at rest; (d) systemic hypertension, requiring medical treatment.
  
  
  RESULTS
  One hundred and forty-one patients underwent surgery for aortic coarctation: 30 neonates, 29 infants, 45 children and 37 adults. Associated lesions were found in 8/37 (=21.6%) adults and in 73/104 (=70.1%) pediatric patients. There were no hospital deaths. During the follow-up there were one late death in the adults group (1/37=2.7%) and three late deaths in the pediatric group (3/104=2.9%), all unrelated with aortic coarctation. Re-operation because of re-coarctation occurred only in ten late survivors of the pediatric group (10/101=9.9%), 9/10 operated on before 1980 (P<0.00001). End-to-end anastomosis, enlarged to the aortic arch in neonates, was associated with the lowest incidence of re-coarctation (P<0.005). A significant (>20 mmHg at rest) pressure gradient was found in none of the adults, and in seven of the 91 pediatric patients (7/91=7.7%) late survivors. Three adults (3/36=8.3%) late survivors are on medical treatment to control systemic hypertension.
  
  
  CONCLUSIONS
  The long-term results of our retrospective study confirm that surgery has to be considered the gold standard for the treatment of aortic coarctation. The interventional angioplasty techniques have to provide long-term outcome at least similar to the results obtained with surgery.
authors.affiliation: Centre Hospitalier Universitaire Vaudois, 46 rue du Bugnon, CH-1011 Lausanne, Switzerland. antonio.corno@chuv.hospvd.ch
authors.forename: A F
authors.initials: AF
authors.lastname: Corno
authors.forename: U
authors.initials: U
authors.lastname: Botta
authors.forename: M
authors.initials: M
authors.lastname: Hurni
authors.forename: M
authors.initials: M
authors.lastname: Payot
authors.forename: N
authors.initials: N
authors.lastname: Sekarski
authors.forename: P
authors.initials: P
authors.lastname: Tozzi
authors.forename: L K
authors.initials: LK
authors.lastname: von Segesser
mesh_terms: D000367:Age Factors; D001017:Aortic Coarctation / Q000150:complications / Q000401:mortality / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000379:methods; D002648:Child; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012189:Retrospective Studies