title: High incidence and increasing prevalence of MS in Enna (Sicily), southern Italy.
abstract: Twenty years after a first survey, a follow-up study was performed on the prevalence of MS in Enna (Sicily), southern Italy. The prevalence of definite MS rose from 53 to 120.2 per 100,000 population. The incidence of definite MS for the period 1986 to 1995 was 5.7 per 100,000 per year. The innermost part of Sicily shows an elevated prevalence of MS, second only to Sardinia in the Mediterranean area.
authors.affiliation: Department of Neuroscience, Azienda Unita Sanitaria Locale 2, Caltanissetta, Italy.
authors.forename: L M
authors.initials: LM
authors.lastname: Grimaldi
authors.forename: G
authors.initials: G
authors.lastname: Salemi
authors.forename: G
authors.initials: G
authors.lastname: Grimaldi
authors.forename: A
authors.initials: A
authors.lastname: Rizzo
authors.forename: R
authors.initials: R
authors.lastname: Marziolo
authors.forename: C
authors.initials: C
authors.lastname: Lo Presti
authors.forename: D
authors.initials: D
authors.lastname: Maimone
authors.forename: G
authors.initials: G
authors.lastname: Savettieri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology*; D012802:Sicily / Q000453:epidemiology; D019371:Topography, Medical