title: [Significance of resistance index and pulsatility index in differential diagnosis of breast neoplasm].
abstract: OBJECTIVE
  To investigate the significance of the resistance index (RI) and pulsatility index (PI) in differential diagnosis between the benign and malignant breast neoplasms.
  
  
  METHODS
  Forty-seven cases of malignant breast tumors, sixty-nine cases of fibroadenomas, seven cases of inflammatory masses and twenty-two cases of mammiplasia were demonstrated on color Doppler flow imaging (CDFI). The measurements of RI and PI of the four groups were recorded respectively and the comparison between benign and malignant neoplasms was made by applying Doppler quantitative analysis.
  
  
  RESULTS
  The color flow was detected in 59.4% of benign breast neoplasms and in 89% of malignant ones respectively (chi 2-test, P < 0.001). There were significant difference between benign and malignant neoplasms on the RI and PI. The malignant neoplasms were characteristic of higher RI (> or = 0.70) and PI (> or = 1.30), which were of satisfactory value for differential diagnosis, amounting to 95.5% of accuracy.
  
  
  CONCLUSIONS
  Combination of both color Doppler analysis and 2D-US might remarkably increase the sensitivity and specificity of differential diagnosis of breast neoplasms. Our results confirmed the significance of color Doppler flow imaging and Doppler quantitative analysis on the differential diagnosis of breast neoplasms.
authors.affiliation: Beijing Hospital, Beijing 100730.
authors.forename: X
authors.initials: X
authors.lastname: Fu
authors.forename: K
authors.initials: K
authors.lastname: Lu
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Huang
authors.forename: Y
authors.initials: Y
authors.lastname: Du
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000098:blood supply; D001943:Breast Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D002277:Carcinoma / Q000098:blood supply / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000098:blood supply / Q000000981:diagnostic imaging; D005348:Fibrocystic Breast Disease / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D008413:Mastitis / Q000000981:diagnostic imaging / Q000503:physiopathology; D008875:Middle Aged; D011673:Pulsatile Flow; D018615:Ultrasonography, Doppler, Color; D016217:Ultrasonography, Mammary; D014655:Vascular Resistance