title: Enterococcal eschars in cutaneous T-cell lymphoma tumors: a distinct clinical entity.
abstract: Cutaneous T-cell lymphomas (CTCL) are extranodal non-Hodgkin's T-cell lymphomas that present in the skin, the most common form being mycosis fungoides. The progression of disease is associated with acquired immunodeficiency and increased susceptibility to infections. Ten CTCL patients presented with dark brown to black eschars overlying ulcerated tumors that cultured positive for Enterococcus and healed with appropriate antibiotic therapy. Enterococcal infections in CTCL tumors may be recognized as a distinct clinical entity requiring specific intervention.
authors.affiliation: Section of Dermatology, Division of Internal Medicine Specialties, M.D. Anderson Cancer Center, Houston, TX 77005, USA. mduvic@mdanderson.org
authors.forename: M
authors.initials: M
authors.lastname: Duvic
authors.forename: A M
authors.initials: AM
authors.lastname: Feasel
authors.forename: C A
authors.initials: CA
authors.lastname: Schwartz
authors.forename: J C
authors.initials: JC
authors.lastname: Cather
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D016983:Enterococcus / Q000302:isolation & purification*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents