Testicular tissue extraction in a young male with 47,XXY Klinefelter's syndrome: potential strategy for preservation of fertility.
OBJECTIVE
To describe a case involving the cryopreservation of testis tissue retrieved from a 15-year-old male teenager with Klinefelter's syndrome.


METHODS
Case report.


METHODS
An academic medical center.


METHODS
A 15-year-old boy with Klinefelter's syndrome.


METHODS
Microsurgical testis sperm extraction with cryopreservation of harvested tissue.


METHODS
Spermatozoa within testis tissue.


RESULTS
Successful extraction and cryopreservation of three vials of sperm-containing testis tissue. No effect on subsequent testosterone levels.


CONCLUSIONS
Testis tissue extraction in the adequately virilized but azoospermic young male with 47, XXY Klinefelter's syndrome may be a strategy to preserve future biological paternity.
Damani
M N
MN
Division of Urology, Boston University School of Medicine, Boston, Massachusetts, USA.
Mittal
R
R
Oates
R D
RD
D000293:Adolescent; D015925:Cryopreservation; D005298:Fertility; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000235:genetics / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D008866:Microsurgery; D013094:Spermatozoa; D013737:Testis / Q000601:surgery*; D020858:Tissue and Organ Harvesting