The importance of postprandial glucose to treatments and outcomes in patients with type 2 diabetes.
A primary goal in the management of diabetes is to prevent its long-term complications through the attainment of tight glycemic control, a complex and incompletely understood metabolic process that involves the interaction of the pancreas, insulin-responsive peripheral tissues, and the liver in regulating fasting blood glucose (FBG) and postprandial glucose (PPG) levels. Whereas much of the clinical management of type 2 diabetes has focused on FBG by measurement of blood glucose levels and glycated hemoglobin levels, mounting evidence has formed strong associations between PPG, the temporally immediate physiological management of a glucose load, and diabetes progression, management, and complications. Application of the research may enable health care systems and providers to more closely mimic a normal glycemic response in individuals with type 2 diabetes, leading to improved clinical outcomes and cost control.
Herman
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ME
The Zitter Group, Oakland, California, USA. mherman@zitter.com
Moore
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D001786:Blood Glucose / Q000032:analysis*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000188:drug therapy*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007003:Hypoglycemia / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000494:pharmacology / Q000627:therapeutic use; D010349:Patient Compliance; D010353:Patient Education as Topic; D019518:Postprandial Period; D016896:Treatment Outcome; D014481:United States
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents