Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).
Photochemotherapy with psoralens and UVA (PUVA) is widely used in the treatment of psoriasis and many other skin conditions. Cutaneous adverse reactions to 8-methoxypsoralen (8-MOP) appear to be rare and may be difficult to distinguish from phototoxicity or UV-induced polymorphic light eruption. We describe a patient who had a systemic allergic contact dermatitis to 8-MOP develop during her second course of PUVA treatment for psoriasis.
Ravenscroft
J
J
Department of Dermatology, Leeds General Infirmary, England. ravo@compuserve.com
Goulden
V
V
Wilkinson
M
M
D000328:Adult; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008730:Methoxsalen / Q000009:adverse effects*; D011701:PUVA Therapy / Q000009:adverse effects*; D010328:Patch Tests; D011565:Psoriasis / Q000188:drug therapy*
D008730:Methoxsalen