Optical imaging of neural activity in multiple auditory cortical fields of guinea pigs.
Neural activity of multiple fields in the auditory cortex of anesthetized guinea pigs in response to pure tones was visualized by optical recording using a voltage-sensitive dye (RH795). Ten auditory fields were identified based on the tonotopic organization and response latency: the core fields consisting of the primary (AI) and secondary (AII) fields and surrounding belt areas consisting of dorso-anterior (DA), dorsal (D), dorso-posterior (DP), posterior (P), ventro-posterior (VP), ventro-medial (VM), ventro-anterior (VA) and ventral (V) fields. Tonotopic organization was observed in all the fields apart from DA, D, DP and V. Spatio-temporal displays suggest that the auditory information spreads from the core fields of AI and AII to belt fields via three distinct (dorsocaudal, caudal and ventrorostral) pathways.
Horikawa
J
J
Department of Neurophysiology, Tokyo Medical and Dental University, Kanda-surugadai 2-3-10, Chiyoda-ku, Tokyo 101-0062, Japan.
Hess
A
A
Nasu
M
M
Hosokawa
Y
Y
Scheich
H
H
Taniguchi
I
I
D000161:Acoustic Stimulation; D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000502:physiology*; D001931:Brain Mapping / Q000295:instrumentation / Q000379:methods*; D001330:Electronic Data Processing / Q000295:instrumentation / Q000379:methods*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005456:Fluorescent Dyes; D006168:Guinea Pigs; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D008856:Microscopy, Fluorescence / Q000295:instrumentation / Q000379:methods; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D013343:Styrenes
D005456:Fluorescent Dyes; C096453:RH 795; D013343:Styrenes