Carboxy-terminal region involved in activity of Escherichia coli TolC.
The Escherichia coli TolC acts as a channel tunnel in the transport of various molecules across the outer membrane. Partial-deletion studies of tolC revealed that the region extending from the 50th to the 60th amino acid residue from the carboxy terminus plays an important role in this transport activity of TolC.
Yamanaka
H
H
Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro, Tokushima 770-8514, Japan.
Izawa
H
H
Okamoto
K
K
D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry* / Q000502:physiology; D001427:Bacterial Toxins / Q000378:metabolism; D001692:Biological Transport; D004768:Enterotoxins / Q000378:metabolism; D004926:Escherichia coli / Q000502:physiology*; D029968:Escherichia coli Proteins; D026901:Membrane Transport Proteins; D013329:Structure-Activity Relationship
D001425:Bacterial Outer Membrane Proteins; D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; D026901:Membrane Transport Proteins; C034151:heat stable toxin (E coli); C073126:tolC protein, E coli