GABA(B) receptors: new tricks by an old dog.
Our understanding of the molecular, structural and pharmacological properties of the GABA(B) receptor has lagged behind that of the GABA(A) receptor for several decades. This situation has changed with the recent cloning of this receptor, revealing an unexpected and highly intriguing complexity of both structure and function.
Hammond
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Department of Anesthesia, University of Iowa, Iowa City 52242, USA. donna-hammond@uiowa.edu
D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D002490:Central Nervous System / Q000378:metabolism; D006801:Humans; D008024:Ligands; D018080:Receptors, GABA-B / Q000737:chemistry / Q000187:drug effects*; D015398:Signal Transduction / Q000187:drug effects
D000700:Analgesics; D008024:Ligands; D018080:Receptors, GABA-B