Cocaine-contaminated allogeneic bone marrow transplantation.
Should a person with history of drug addiction be categorically denied as a bone marrow donor? The answer to the question is controversial. We report a case of allogeneic bone marrow transplantation for refractory acute myeloid leukemia preceded by essential thrombocythemia. The donor used cocaine and marijuana the night before the bone marrow harvest.
Keung
Y K
YK
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Tex., USA. ykeung@wfubmc.edu
Morgan
D
D
Cobos
E
E
D000744:Anemia, Hemolytic, Autoimmune / Q000209:etiology; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000209:etiology; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D019970:Cocaine-Related Disorders; D003561:Cytarabine / Q000008:administration & dosage; D003630:Daunorubicin / Q000008:administration & dosage; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D008297:Male; D002189:Marijuana Abuse; D008875:Middle Aged; D012008:Recurrence; D016879:Salvage Therapy; D013920:Thrombocythemia, Essential; D014019:Tissue Donors; D009927:Tissue and Organ Procurement / Q000592:standards*; D014184:Transplantation, Homologous / Q000009:adverse effects
D003561:Cytarabine; D003630:Daunorubicin