New method for evaluation of virucidal activity of antiseptics and disinfectants.
Counting culturable viruses adsorbed to cellulose nitrate filters (the VIRADEN method) is proposed as a simple procedure for the evaluation of the virucidal activity of antiseptics and disinfectants. The virucidal activities of two different doses of iodine, chlorine, glutaraldehyde, and chlorhexidine digluconate on poliovirus 1 were tested with a standardized procedure and with the VIRADEN method. The two procedures assayed provided similar results.
Papageorgiou
G T
GT
Microbiology Section, State General Laboratory, Ministry of Health, Nicosia, Cyprus.
Mocé-Llivina
L
L
Jofre
J
J
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D002713:Chlorine / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D006801:Humans; D007455:Iodine / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods; D017955:Poliovirus / Q000187:drug effects* / Q000254:growth & development; D010948:Viral Plaque Assay
D000891:Anti-Infective Agents, Local; D004202:Disinfectants; D002713:Chlorine; D007455:Iodine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine