Attempts at formulation of syrup with theophylline.
The aim of this study was attempt to formulate syrup with theophylline. This form of drug would enable easy adjustment of individual doses of drug for therapeutic purposes in children. Due to poor solubility of theophylline in water, attempts at increasing of its solubility by adding special adjuvant substances, which could increase solubility and stabilise the obtained solution, were of particular importance.
Welk
B
B
Department of Biopharmacy, Medical Unviersity of Lódź.
Kurczewska
U
U
Orszulak-Michalak
D
D
D001993:Bronchodilator Agents / Q000008:administration & dosage* / Q000737:chemistry*; D002138:Calibration; D004355:Drug Stability; D007202:Indicators and Reagents; D019999:Pharmaceutical Solutions; D013056:Spectrophotometry, Ultraviolet; D013806:Theophylline / Q000008:administration & dosage* / Q000737:chemistry*
D001993:Bronchodilator Agents; D007202:Indicators and Reagents; D019999:Pharmaceutical Solutions; D013806:Theophylline