title: Cerebellopontine angle tumor composed of Schwann and meningeal proliferations.
abstract: Tumors found in the cerebellopontine angle are predominantly vestibular schwannomas. Mixed tumors found within the cerebellopontine angle are thought to be exceedingly rare and exclusively associated with neurofibromatosis 2. We report a case of a mixed tumor composed of Schwann and meningeal cell proliferations in a patient who was not diagnosed as having neurofibromatosis 2. Mixed tumors composed of neoplastic Schwann and meningeal cells have rarely been reported. However, new evidence indicates that these mixed tumors may be more common than was previously thought and may have an interrelated mechanism of pathogenesis. Although the case we describe does not fulfill the current diagnostic criteria for neurofibromatosis 2, a presumptive diagnosis was given, suggesting that the current diagnostic criteria for neurofibromatosis 2 may be too narrow.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, The University of Iowa, Iowa City, USA.
authors.forename: A F
authors.initials: AF
authors.lastname: Chen
authors.forename: R N
authors.initials: RN
authors.lastname: Samy
authors.forename: B J
authors.initials: BJ
authors.lastname: Gantz
mesh_terms: D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002530:Cerebellopontine Angle / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000601:surgery; D016518:Neurofibromatosis 2 / Q000175:diagnosis; D009464:Neuroma, Acoustic / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed