title: SQUID biomagnetometry of the uterine arteries in normal and pre-eclamptic pregnancies.
abstract: OBJECTIVE
  This study was designed to investigate the hemodynamics of the uteroplacental circulation in normal and pre-eclamptic pregnancies using the biomagnetometer SQUID.
  
  
  METHODS
  Twenty-two pregnancies complicated by pre-eclampsia and 49 normal pregnancies were included in this study. All were near term. Biomagnetic signals were recorded from the uterine arteries. After statistical Fourier analysis, the findings were designated in terms of spectral amplitudes as high (140-300 fT/square root of Hz), low (50-110 fT/square root of Hz) and borderline (111-139 fT/square root of Hz).
  
  
  RESULTS
  The uterine artery waveforms and the corresponding spectral densities were of high amplitudes in most (89.7%) normal pregnancies and of low amplitudes in most (81.8%) pregnancies complicated by pre-eclampsia (p < 0.005). These findings were of statistical significance and were correlated with fetal heart rate (FHR) monitoring, pH, Apgar score at 1 and 5 minutes and birth weight percentiles: high amplitude cases were related with normal FHR patterns, pH > 7.25, Apgar score > 7 and birth weight > 75th percentile, while low amplitude recordings were connected with abnormal FHR patterns, pH < 7.25, Apgar score < 7, and birth weight < 10th percentile (8 cases) and < 50th percentile (10 cases).
  
  
  CONCLUSIONS
  Biomagnetic measurement of the uterine artery flow, is a promising procedure in assessing fetal health, especially in high-risk pregnancies.
authors.affiliation: Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
authors.forename: P
authors.initials: P
authors.lastname: Anastasiadis
authors.forename: P A
authors.initials: PA
authors.lastname: Anninos
authors.forename: A
authors.initials: A
authors.lastname: Kotini
authors.forename: K
authors.initials: K
authors.lastname: Avgidou
authors.forename: G
authors.initials: G
authors.lastname: Galazios
authors.forename: V
authors.initials: V
authors.lastname: Liberis
mesh_terms: D000293:Adolescent; D000328:Adult; D001034:Apgar Score; D001724:Birth Weight; D001783:Blood Flow Velocity / Q000502:physiology; D005260:Female; D006340:Heart Rate, Fetal; D006801:Humans; D007231:Infant, Newborn; D008280:Magnetics; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D014599:Uterus / Q000098:blood supply*