Tissue-specific effects of peptides.
Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures. These peptides produced tissue-specific effects: they stimulated the growth of explants from tissues, whose cytomedins (peptide complexes) were used for chemical synthesis.
Khavinson
V K
VK
St. Petersburg Institute of Bioregulation and Gerontology, Northwestern Division of the Russian Academy of Medical Sciences. ibg@medport.ru
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002540:Cerebral Cortex / Q000166:cytology / Q000187:drug effects; D006133:Growth Substances / Q000494:pharmacology*; D008099:Liver / Q000166:cytology / Q000187:drug effects; D009924:Organ Culture Techniques; D009928:Organ Specificity; D010455:Peptides / Q000494:pharmacology*; D010870:Pineal Gland / Q000166:cytology / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects
D006133:Growth Substances; D010455:Peptides