Off-pump coronary artery bypass grafting for acute heparin-induced thrombocytopenia.
Surgical revascularization of coronary arteries is problematic for patients with heparin-induced thrombocytopenia because the available nonheparin anticoagulants cannot be reversed pharmacologically. We used three-vessel off-pump coronary artery bypass grafting in a patient with heparin-induced thrombocytopenia, as it allowed us to use substantially lower doses of nonheparin anticoagulant (danaparoid sodium), compared with procedures requiring cardiopulmonary bypass.
Warkentin
T E
TE
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Dunn
G L
GL
Cybulsky
I J
IJ
D000208:Acute Disease; D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D001026:Coronary Artery Bypass / Q000379:methods*; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000601:surgery*
D000925:Anticoagulants; D006493:Heparin