Preclinical phase of polycythemia vera in pregnancy.
BACKGROUND
In some cases, complications of pregnancy are related to thrombophilia. We describe a preclinical phase of polycythemia vera.


METHODS
A woman, who experienced perinatal deaths in her first two pregnancies, was diagnosed with polycythemia vera during antenatal counseling for a third pregnancy. During this pregnancy, phlebotomies, low molecular weight heparin, and low-dose aspirin treatments resulted in the delivery of a healthy baby.


CONCLUSIONS
Polycythemia vera is a rare condition in women of childbearing age and can exist in a preclinical phase for many years. During pregnancy, it can cause severe but preventable thrombotic complications of placental origin.
Subtil
D
D
Hôpital Jeanne de Flandre and Hôpital Cardiologique, Centre Hospitalier Régional et Universitaire de Lille, Lille Cedex, France. d-subtil@chru-lille.fr
Deruelle
P
P
Trillot
N
N
Jude
B
B
D003376:Counseling; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011087:Polycythemia Vera / Q000175:diagnosis* / Q000628:therapy; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000628:therapy; D011256:Pregnancy Outcome