Level of injury and hormone profiles in spinal cord-injured men.
OBJECTIVE
To evaluate the level of injury and endocrine profiles in men with spinal cord injury (SCI).


METHODS
Seventy-six men with SCI at different levels were studied, using uninjured normal and infertile subjects as controls.


RESULTS
Compared with normal controls, the subjects with SCI (50%) had lower serum levels of luteinizing hormone, follicle-stimulating hormone, and testosterone. Subjects with T8-T11 and T12-L5 injury had the highest and lowest incidence of hormonal abnormalities, respectively. All subjects with hyperprolactinemia (n = 5) had T8-T11 injuries.


CONCLUSIONS
The results of our study indicate that subjects with SCI have an altered central neurotransmitter tone, and the likelihood of these abnormalities (hypogonadotropism) are higher in men with low thoracic SCI.
Safarinejad
M R
MR
Department of Urology, Division of Urology and Renal Transplantation, Military University of Medical Sciences, Air Force Hospital, Tehran, Iran.
D000328:Adult; D016022:Case-Control Studies; D002574:Cervical Vertebrae; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood; D008159:Lumbar Vertebrae; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013119:Spinal Cord Injuries / Q000097:blood* / Q000473:pathology; D013739:Testosterone / Q000097:blood*; D013904:Thoracic Vertebrae
D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone