[One-week application of terbinafine cream compared with four-week application in treatment of Tinea pedis].
The possibility of one-week application of terbinafine cream for tinea pedis was studied in a double-blind test at four institutes, comparing four-week application as a control. Of a total of forty-three patients studied, nineteen were randomized into a four-week application group, Group I, and twenty into a one-week application group, Group II. Group I was evaluated as moderate to extremely useful in twelve (63.2%) of the nineteen patients and Group II in twelve (60.0%) of the twenty patients. No statistical differences were observed between two groups. These findings appeared to indicate that the short term, one-week application of terbinafine cream had results equivalent to the four-week application. This short-term treatment which aids in improving patient compliance and reducing the total amount of drug applied, thus lowering drug cost, is viewed as a useful way of treating tinea pedis.
Sugiura
M
M
Department of Dermatology, Shimizu City Hospital, 1231 Miyakami, Shimizu-shi, Shizuoka 424-8638, Japan.
Hata
Y
Y
Fukuda
T
T
Ishizaki
S
S
Hanyaku
H
H
Naka
W
W
Harada
T
T
Nishikawa
T
T
D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000008:administration & dosage*; D004304:Dosage Forms; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009281:Naphthalenes / Q000008:administration & dosage*; D000077291:Terbinafine; D013997:Time Factors; D014008:Tinea Pedis / Q000188:drug therapy*; D016896:Treatment Outcome
D000935:Antifungal Agents; D004304:Dosage Forms; D009281:Naphthalenes; D000077291:Terbinafine