Efficacy of once-daily clindamycin hydrochloride in the treatment of superficial bacterial pyoderma in dogs.
Twenty-one dogs with canine superficial bacterial pyoderma were treated with clindamycin at a dosage of approximately 11 mg/kg body weight, q 24 hours, given orally for 14 to 42 days. All dogs were reexamined on days 14, 28, and, if necessary, 42 and given a clinical score of excellent (i.e., complete remission), good (i.e., primary lesions resolved but secondary lesions evident), fair (i.e., partial improvement but primary lesions still evident), or poor (i.e., no improvement or worsening of the lesions). A clinical score of excellent was obtained in 71.4% (15/21) of the dogs in this study within 14 to 28 days.
Bloom
P B
PB
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Veterinary Medical Center, Michigan State University, East Lansing 48824-1314, USA.
Rosser
E J
EJ
D000284:Administration, Oral; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000494:pharmacology; D002981:Clindamycin / Q000008:administration & dosage* / Q000494:pharmacology; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004334:Drug Administration Schedule; D005260:Female; D008297:Male; D008826:Microbial Sensitivity Tests; D011711:Pyoderma / Q000188:drug therapy / Q000662:veterinary*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000662:veterinary*; D013210:Staphylococcus / Q000187:drug effects; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D002981:Clindamycin