Relation between the degree of acetylation and the electrostatic properties of chitin and chitosan.
A series of chitosan/chitin samples with DA's varying between 5.2 and 89% was prepared from the reacetylation under soft conditions of a unique chitosan sample allowing the preservation of the chain distribution. The study of the variation of pH for the same concentration of amine groups, at different ionic strengths, on the scale of DA's allows us to extrapolate the variation of pKa at dissociation degrees (alpha) 0 and 1. A modeling of all the curves was obtained by means of only one equation. Then, for given concentration of chitosan and ionic strength, it is possible to predict the pH of the solution whatever the DA and alpha. The role of DA through the participation of hydrophobic interactions and hydrogen bondings on the electrostatic parameters is discussed. The results allow a better understanding of some physicochemical and biological properties of chitosan and chitin.
Sorlier
P
P
Laboratoire des Materiaux Polymères et des Biomatériaux (UMR-CNRS 5627), ISTIL, Domaine Scientifique de la Doua, 15 Boulevard Latarjet, 69622, Villeurbanne, France.
Denuzière
A
A
Viton
C
C
Domard
A
A
D000107:Acetylation; D000818:Animals; D001704:Biopolymers / Q000737:chemistry; D002686:Chitin / Q000031:analogs & derivatives / Q000737:chemistry*; D048271:Chitosan; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D046911:Macromolecular Substances; D008956:Models, Chemical; D009994:Osmolar Concentration; D012996:Solutions; D055672:Static Electricity
D001704:Biopolymers; D046911:Macromolecular Substances; D012996:Solutions; D002686:Chitin; D048271:Chitosan