Effect of emotional stress in pregnant rats on brain development of their progeny.
We compared 21- and 40-day old rat pups from rats subjected to emotional stress in trimester III and from intact females. The width of the parietal cortex and the size of layer V neuron cytoplasm and nuclei in the anterior parietal lobe and hippocampus were increased in 21-day-old test pups compared to age-matched controls. In 40-day-old test pups, neurons in layers II and V of the parietal lobe and layer II of the anterior parietal lobe and hippocampal neurons were enlarged compared to the control.
Ryzhavskii
B Y
BY
Department of Histology, Far-East State Medical Institute.
Sokolova
T V
TV
Fel'dsherov
Y I
YI
Uchakina
R V
RV
Sapozhnikov
Y A
YA
Malysheva
E N
EN
D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism; D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001835:Body Weight; D001921:Brain / Q000033:anatomy & histology / Q000166:cytology / Q000254:growth & development*; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D006624:Hippocampus / Q000166:cytology / Q000254:growth & development; D008297:Male; D008431:Maternal-Fetal Exchange; D009474:Neurons / Q000166:cytology; D009929:Organ Size; D010053:Ovary / Q000378:metabolism; D010296:Parietal Lobe / Q000166:cytology / Q000254:growth & development; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011270:Pregnancy, Animal / Q000523:psychology*; D012313:RNA / Q000032:analysis; D051381:Rats; D013315:Stress, Psychological; D013737:Testis / Q000378:metabolism; D014018:Tissue Distribution
D012313:RNA; D015096:3-Hydroxysteroid Dehydrogenases