title: Clinical studies of bioabsorbable poly-L-lactide sternal coaptation pins.
abstract: BACKGROUND
  Median sternotomy has become the most commonly used incision in cardiac surgery. Since sternal dehiscence, however, is a major complication, we used bioabsorbable poly-L-lactide (P-L-LA) sternal coaptation pins for sternal closure to prevent it.
  
  
  METHODS
  From February 1998 to October 1999, 99 patients (64 men, 35 women; mean age, 63+/-1.2 years) underwent median sternotomy for cardiac surgery using sternal coaptation pins. Nineteen patients had diabetes mellitus and seven had renal failure. In closure, two sternal pins were inserted into the bone marrow of the sternum, one into the manubrium, the other into the body, and the sternum was sutured with five stainless steel wires.
  
  
  RESULTS
  Five patients died in the hospital. The causes of death were cardiac failure in two patients, respiratory problem in two and perforation of the stomach in one. The average length of hospitalization was 2 4.5+/-2.5 days. Sternal dehiscence occurred in one patient and mediastinitis in four. There was no bleeding from the bone marrow and no complication related to the use of the sternal pins.
  
  
  CONCLUSIONS
  P-L-LA sternal pins were easy to insert and may be effective in preventing dehiscence of the sternum.
authors.affiliation: Division of Cardiovascular Surgery, National Toyohashi, Higashi Hospital, Aichi, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Okawa
authors.forename: N
authors.initials: N
authors.lastname: Ishida
authors.forename: M
authors.initials: M
authors.lastname: Toyama
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
mesh_terms: D020341:Absorbable Implants; D000368:Aged; D000369:Aged, 80 and over; D001858:Bone Nails; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011091:Polyesters; D013249:Sternum / Q000601:surgery*; D013529:Surgical Wound Dehiscence / Q000209:etiology
chemical_list: D011091:Polyesters; C033616:poly(lactide)