title: Circulating fetal RNA in maternal plasma.
abstract: The discovery of cell-free nucleic acids in plasma has opened up new possibilities for noninvasive clinical diagnosis. We demonstrate the presence of cell-free fetal RNA in maternal plasma, indicating that plasma fetal RNA might be used as a marker for noninvasive prenatal diagnosis.
authors.affiliation: Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR.
authors.forename: L L
authors.initials: LL
authors.lastname: Poon
authors.forename: T N
authors.initials: TN
authors.lastname: Leung
authors.forename: T K
authors.initials: TK
authors.lastname: Lau
authors.forename: Y M
authors.initials: YM
authors.lastname: Lo
mesh_terms: D015415:Biomarkers; D005260:Female; D005333:Fetus / Q000378:metabolism*; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012313:RNA / Q000097:blood*
chemical_list: D015415:Biomarkers; D012313:RNA