title: Tn7: smarter than we thought.
abstract: A notable feature of transposable elements--segments of DNA that can move from one position to another in genomes--is that they are highly prevalent, despite the fact that their translocation can result in mutation. The bacterial transposon Tn7 uses an elaborate system of target-site selection pathways that favours the dispersal of Tn7 in diverse hosts as well as minimizing its negative effects.
authors.affiliation: Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Peters
authors.forename: N L
authors.initials: NL
authors.lastname: Craig
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D001426:Bacterial Proteins / Q000502:physiology; D004247:DNA / Q000737:chemistry*; D004251:DNA Transposable Elements / Q000235:genetics* / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000502:physiology; D029968:Escherichia coli Proteins; D008954:Models, Biological; D008957:Models, Genetic
chemical_list: D001426:Bacterial Proteins; D004251:DNA Transposable Elements; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; C098908:TnsA protein, E coli; C069633:TnsB protein, E coli; C074940:TnsC protein, E coli; D000255:Adenosine Triphosphate; D004247:DNA