title: Non diethylstilbesterol induced vaginal adenosis--a case series and review of literature.
abstract: Non diethylstilbestrol induced vaginal adenosis has a reported incidence of about 10% in adult women. Although in some, it may be an insignificant coincidental finding, it is probably under-diagnosed even in symptomatic women. Little is known about the aetiology, pathogenesis, symptomatology and management of this poorly understood condition. Our experience with the four cases of vaginal adenosis unrelated to diethylstilbestrol (DES) exposure and a review of the literature will probably shed some light on this, as it still remains an enigma in gynaecological oncology.
authors.affiliation: Specialist Registrar, Obstetrics and Gynaecology, Hartlepool General Hospital, UK.
authors.forename: I
authors.initials: I
authors.lastname: Chattopadhyay
authors.forename: D J
authors.initials: DJ
authors.lastname: Cruickshan
authors.forename: M
authors.initials: M
authors.lastname: Packer
mesh_terms: D000328:Adult; D002273:Carcinogens; D004054:Diethylstilbestrol / Q000009:adverse effects; D004848:Epithelium / Q000473:pathology; D004968:Estrogens, Non-Steroidal / Q000009:adverse effects; D005260:Female; D006801:Humans; D008679:Metaplasia; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology*; D014621:Vagina / Q000187:drug effects / Q000473:pathology*; D014625:Vaginal Neoplasms / Q000139:chemically induced / Q000473:pathology*
chemical_list: D002273:Carcinogens; D004968:Estrogens, Non-Steroidal; D004054:Diethylstilbestrol