A new galloylglucoside from Cleyera ochnacea DC.
A new galloylglucoside, 3-hydroxy-5-methylphenol 1-O-beta-D-(6'-galloyl)glucopyranoside (1) was isolated from Cleyera ochnacea DC. (Theaceae). Its structure was elucidated on the basis of chemical and spectral analysis. Compound 1 showed inhibitory activity against rat cerebellar nitric oxide synthase (NOS).
Iwakawa
T
T
Aburahi Laboratories, Shionogi & Co, Ltd, Koka, Shiga, Japan.
Tanaka
Y
Y
Takashima
A
A
D000818:Animals; D002531:Cerebellum / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D047348:Hydrolyzable Tannins; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D052247:Nitric Oxide Synthase Type II; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D051381:Rats; D013634:Tannins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D028242:Theaceae / Q000737:chemistry*
D004791:Enzyme Inhibitors; D005960:Glucosides; D047348:Hydrolyzable Tannins; D010936:Plant Extracts; D013634:Tannins; C060474:glucogallin; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; C496318:Nos2 protein, rat