title: Pregnancy/implantation rates as related to age following transfer of frozen embryos produced by ICSI.
abstract: A study has suggested that one drawback of ICSI is that if these embryos are cryopreserved they have lower implantation rates after thawing and transfer as compared to other frozen embryos derived from conventional oocyte insemination. Other studies have not shown such adverse effects on pregnancy rates following frozen embryo transfer (ET) of embryos formed by ICSI. The study presented here evaluated the largest number of frozen ET cycles of embryos following ICSI, which were compared to couples having frozen ET with embryos formed by conventional insemination. In women age 39 and younger, the clinical, viable, pregnancy rates and implantation rates were very similar. Similar rates were reached for the older group. These data convincingly demonstrate that fertilization by ICSI does not adversely effect the implanting capacity of frozen-thawed embryos.
authors.affiliation: The University of Medicine/Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Check
authors.forename: J H
authors.initials: JH
authors.lastname: Check
authors.forename: D
authors.initials: D
authors.lastname: Summers-Chase
authors.forename: K
authors.initials: K
authors.lastname: Swenson
authors.forename: W
authors.initials: W
authors.lastname: Yuan
mesh_terms: D000328:Adult; D000367:Age Factors; D015925:Cryopreservation; D010064:Embryo Implantation / Q000502:physiology*; D004624:Embryo Transfer; D004622:Embryo, Mammalian; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D013094:Spermatozoa