n-3 Polyunsaturated fatty acids, fish, and nonfatal acute myocardial infarction.
BACKGROUND
The relation between n-3 polyunsaturated fatty acids (PUFAs), fish intake, and risk of coronary heart disease is controversial.


RESULTS
An Italian case-control study including 507 patients with nonfatal acute myocardial infarction (AMI) and 478 hospital controls found a multivariate odds ratio (OR) of 0.67 (95% CI, 0.47 to 0.95) for the highest n-3 PUFA intake and 0.68 (95% CI, 0.47 to 0.98) for an intake of >1 portion of fish per week compared with >/=2 portions per week.


CONCLUSIONS
Small amounts of n-3 PUFAs may be inversely related to AMI risk in this low-risk population.
Tavani
A
A
Istituto di Ricerche Farmacologiche "Mario Negri", Istituto di Statistica Medica e Biometria, Università degli Studi di Milano, Milan, Italy. tavani@marionegri.it
Pelucchi
C
C
Negri
E
E
Bertuzzi
M
M
La Vecchia
C
C
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000818:Animals; D016022:Case-Control Studies; D004032:Diet; D015525:Fatty Acids, Omega-3; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage; D005260:Female; D005399:Fishes; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000517:prevention & control; D016017:Odds Ratio; D018570:Risk Assessment; D014280:Triglycerides / Q000008:administration & dosage
D015525:Fatty Acids, Omega-3; D005231:Fatty Acids, Unsaturated; D014280:Triglycerides; C077446:Pikasol