title: Testicular tissue extraction in a young male with 47,XXY Klinefelter's syndrome: potential strategy for preservation of fertility.
abstract: OBJECTIVE
  To describe a case involving the cryopreservation of testis tissue retrieved from a 15-year-old male teenager with Klinefelter's syndrome.
  
  
  METHODS
  Case report.
  
  
  METHODS
  An academic medical center.
  
  
  METHODS
  A 15-year-old boy with Klinefelter's syndrome.
  
  
  METHODS
  Microsurgical testis sperm extraction with cryopreservation of harvested tissue.
  
  
  METHODS
  Spermatozoa within testis tissue.
  
  
  RESULTS
  Successful extraction and cryopreservation of three vials of sperm-containing testis tissue. No effect on subsequent testosterone levels.
  
  
  CONCLUSIONS
  Testis tissue extraction in the adequately virilized but azoospermic young male with 47, XXY Klinefelter's syndrome may be a strategy to preserve future biological paternity.
authors.affiliation: Division of Urology, Boston University School of Medicine, Boston, Massachusetts, USA.
authors.forename: M N
authors.initials: MN
authors.lastname: Damani
authors.forename: R
authors.initials: R
authors.lastname: Mittal
authors.forename: R D
authors.initials: RD
authors.lastname: Oates
mesh_terms: D000293:Adolescent; D015925:Cryopreservation; D005298:Fertility; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000235:genetics / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D008866:Microsurgery; D013094:Spermatozoa; D013737:Testis / Q000601:surgery*; D020858:Tissue and Organ Harvesting