Meiosis: how to create a specialized cell cycle.
During the meiotic cell cycle, a single round of DNA replication precedes two nuclear divisions. Recent work has shown that the proteins controlling the mitotic cell cycle are either replaced by homologous proteins only expressed during the meiotic cell cycle or modulated by meiosis-specific factors to bring about this specialized cell cycle.
Lee
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Center for Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, E17-233, 40 Ames Street, Cambridge, MA 02139, USA.
Amon
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D000818:Animals; D002453:Cell Cycle; D002503:Centromere / Q000502:physiology; D002842:Chromatids / Q000235:genetics; D020090:Chromosome Segregation; D016193:G1 Phase; D016195:G2 Phase; D018386:Kinetochores / Q000502:physiology; D008540:Meiosis; D008957:Models, Genetic; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics; D012568:Schizosaccharomyces / Q000166:cytology / Q000235:genetics; D012854:Sister Chromatid Exchange