Directional specificity of prostate stromal to epithelial cell communication via FGF7/FGFR2 is set by cell- and FGFR2 isoform-specific heparan sulfate.
Kan
M
M
Uematsu
F
F
Wu
X
X
Wang
F
F
D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D002465:Cell Movement / Q000187:drug effects; D004847:Epithelial Cells / Q000502:physiology*; D051523:Fibroblast Growth Factor 7; D005346:Fibroblast Growth Factors / Q000502:physiology*; D006497:Heparan Sulfate / Q000494:pharmacology*; D008297:Male; D011467:Prostate / Q000166:cytology; D020033:Protein Isoforms; D020794:Receptor Protein-Tyrosine Kinases / Q000502:physiology*; D051497:Receptor, Fibroblast Growth Factor, Type 2; D017468:Receptors, Fibroblast Growth Factor / Q000502:physiology*; D017154:Stromal Cells / Q000502:physiology*
D051523:Fibroblast Growth Factor 7; D005346:Fibroblast Growth Factors; D006497:Heparan Sulfate; D020033:Protein Isoforms; D020794:Receptor Protein-Tyrosine Kinases; D051497:Receptor, Fibroblast Growth Factor, Type 2; D017468:Receptors, Fibroblast Growth Factor