title: Total intravenous anaesthesia in a patient with familial hypokalaemic periodic paralysis.
abstract: A 35-year-old woman with known familial hypokalaemic periodic paralysis received general anaesthesia for reduction of bilateral breast hyperplasia. Uncomplicated general anaesthesia was performed using a propofol target-controlled infusion, remifentanil infusion and bolus doses of mivacurium with neuromuscular function monitoring. Plasma potassium concentrations were controlled intermittently in the peri-operative period and supplemented to achieve normokalaemia. Despite continuous substitution, an episode of low plasma potassium concentration occurred during the recovery period; this was without any clinical signs of muscle paralysis or respiratory distress.
authors.affiliation: Institute of Anaesthesiology, Triemli City Hospital Zurich, Birmensdorferstr. 497, 8063 Zurich, Switzerland. christoph.hofer@triemli.stzh.ch
authors.forename: C
authors.initials: C
authors.lastname: Hofer
authors.forename: M P
authors.initials: MP
authors.lastname: Zalunardo
authors.forename: A
authors.initials: A
authors.lastname: Zollinger
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid; D000768:Anesthesia, General / Q000379:methods*; D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000097:blood* / Q000150:complications; D007546:Isoquinolines; D000077590:Mivacurium; D003473:Neuromuscular Nondepolarizing Agents; D010245:Paralyses, Familial Periodic / Q000097:blood* / Q000150:complications; D010880:Piperidines; D015742:Propofol; D000077208:Remifentanil
chemical_list: D000701:Analgesics, Opioid; D018686:Anesthetics, Intravenous; D007546:Isoquinolines; D003473:Neuromuscular Nondepolarizing Agents; D010880:Piperidines; D000077590:Mivacurium; D000077208:Remifentanil; D015742:Propofol