title: Parathyroid hyperplasia: an unusual cause of neonatal hypercalcemia.
abstract: Primary hyperparathyroidism (PHPT) in infants is caused by parathyroid chief cell hyperplasia. Patients present with symptoms of chronic hypercalcemia, such as failure to thrive, irritability, abdominal pain, and anorexia. Medical therapy is inadequate, often resulting in chronic hypercalcemia or death. Partial or total surgical removal of the parathyroid gland is the preferred treatment. We describe a case of a 7-month-old infant with PHPT secondary to hyperplasia successfully treated with a subtotal parathyroidectomy.
authors.affiliation: Children's Hospital of New Orleans, LSU Health Sciences Center, Division of Otolaryngology, 200 Henry Clay Ave, New Orleans LA 70118, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Payne
authors.forename: D L
authors.initials: DL
authors.lastname: Suskind
authors.forename: A
authors.initials: A
authors.lastname: Vargas
authors.forename: R
authors.initials: R
authors.lastname: Craver
authors.forename: D C
authors.initials: DC
authors.lastname: Liu
mesh_terms: D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006961:Hyperparathyroidism / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D006965:Hyperplasia / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D007223:Infant; D010280:Parathyroid Glands / Q000473:pathology / Q000601:surgery; D016105:Parathyroidectomy