title: [Principle and biological applications of protein chip system].
abstract: Protein chip system is a next generation chip technology, which can be used as one of the most important tools for proteomics research. Protein chip system uses different methods to immobilize proteins and detect protein binding on sensor chips from DNA chip system. Protein chip system has a very wide range of applications, including protein interaction study, discovery of disease marker, differential protein expression profiling, peptide mapping, and protein purification.
authors.affiliation: Biomolecule Research Team, Korea Basic Science Institute, Taejon.
authors.forename: K S
authors.initials: KS
authors.lastname: Ha
mesh_terms: D020869:Gene Expression Profiling; D005819:Genetic Markers; D006031:Glycosylation; D007700:Kinetics; D008024:Ligands; D025202:Molecular Diagnostic Techniques; D020411:Oligonucleotide Array Sequence Analysis; D010766:Phosphorylation; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D020543:Proteome; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D020349:Surface Plasmon Resonance
chemical_list: D005819:Genetic Markers; D008024:Ligands; D011506:Proteins; D020543:Proteome