Identification of a major gene regulating complex social behavior.
Colony queen number, a major feature of social organization in fire ants, is associated with worker genotypes at the gene Gp-9. We sequenced Gp-9 and found that it encodes a pheromone-binding protein, a crucial molecular component in chemical recognition of conspecifics. This suggests that differences in worker Gp-9 genotypes between social forms may cause differences in workers' abilities to recognize queens and regulate their numbers. Analyses of sequence evolution indicate that regulation of social organization by Gp-9 is conserved in South American fire ant species exhibiting social polymorphism and suggest that positive selection has driven the divergence between the alleles associated with alternate social organizations. This study demonstrates that single genes of major effect can underlie the expression of complex behaviors important in social evolution.
Krieger
Michael J B
MJ
Department of Entomology, University of Georgia, Athens, GA 30602-2603, USA. mkrieger@arches.uga.edu
Ross
Kenneth G
KG
D000483:Alleles; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D000818:Animals; D001000:Ants / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D001118:Argentina; D001483:Base Sequence; D001522:Behavior, Animal; D005075:Biological Evolution; D001938:Brazil; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D019143:Evolution, Molecular; D005260:Female; D017344:Genes, Insect; D005838:Genotype; D019476:Insect Proteins / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012333:RNA, Messenger / Q000737:chemistry / Q000235:genetics; D012919:Social Behavior; D014481:United States
D002352:Carrier Proteins; C440903:Gp-9 protein, Solenopsis; D019476:Insect Proteins; D012333:RNA, Messenger