title: Features of age-related macular degeneration on optical coherence tomography.
abstract: OBJECTIVE
  To describe Optical Coherence Tomographic (OCT) findings in age-related macular lesions.
  
  
  METHODS
  We selected 6 patients with characteristic features of age-related macular disease on OCT, 4 of whom presented with Choroidal New Vessels (CNV). OCT is analogous to ultrasound, except that light is used instead of sound. The reflected light is analysed with the technique of low-coherence interferometry.
  
  
  RESULTS
  Classic CNV present with well-defined boundaries on OCT, whereas occult CNV can present with well- or poorly defined boundaries. Findings in Chronic Central Serous Chorioretinopathy (CSCR) and Adult Onset Vitelliform Dystrophy (AOVD) need angiographic correlation when compared to findings in CNV.
  
  
  CONCLUSIONS
  OCT cannot replace conventional diagnostic techniques in exsudative Age-related Macular Degeneration. Although it accurately depicts associated changes and especially the associated serous detachment in macular disease, the imaging of neovascular membranes faces limited penetration and resolution. The interpretation of the tomograms requires further clinico-histological correlation.
authors.affiliation: Department of Ophthalmology, Ghent University.
authors.forename: W
authors.initials: W
authors.lastname: Van Kerckhoven
authors.forename: B
authors.initials: B
authors.lastname: Lafaut
authors.forename: I
authors.initials: I
authors.lastname: Follens
authors.forename: J J
authors.initials: JJ
authors.lastname: De Laey
mesh_terms: D000368:Aged; D002825:Chorioretinitis / Q000175:diagnosis; D020256:Choroidal Neovascularization / Q000175:diagnosis* / Q000601:surgery; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D053685:Laser Therapy; D008028:Light Coagulation; D008268:Macular Degeneration / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D012008:Recurrence