title: Predictors of advanced stage colorectal cancer diagnosis: results of a population-based study.
abstract: While colon cancer is a leading cause of morbidity and mortality among men and women, little is known about demographic variables associated with advanced stage diagnosis at diagnosis. We examined the relationship of age, gender, income, education, marital status, smoking status, urban versus rural residence, and proximal versus distal tumor location on stage at diagnosis. Data from Florida statewide cancer registry for the year 1994 with over 8,933 cases of colorectal cancer was analyzed. Using multivariate analysis, an odds ratio of being diagnosed with advanced stage disease was determined for each demographic variable. We found a significantly increased probability (P < .05) of diagnosis with advanced stage disease for distal lesions in middle-aged persons, smokers, and those with higher education or lower income status. If these findings are verified, they may suggest a group that warrants targeted screening intervention or programs over and above today's current colorectal screening recommendations.
authors.affiliation: Department of Family Medicine, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa 33612, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Campbell
authors.forename: J M
authors.initials: JM
authors.lastname: Ferrante
authors.forename: E C
authors.initials: EC
authors.lastname: Gonzalez
authors.forename: R G
authors.initials: RG
authors.lastname: Roetzheim
authors.forename: N
authors.initials: N
authors.lastname: Pal
authors.forename: A
authors.initials: A
authors.lastname: Herold
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000517:prevention & control; D000367:Age Factors; D000368:Aged; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D004493:Education; D005260:Female; D006801:Humans; D007182:Income; D008297:Male; D017533:Marital Status; D009367:Neoplasm Staging; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking