title: Profile of familial breast cancer in Alexandria, Egypt.
abstract: Nearly two thirds of the cancers which will appear in the next 25 years will occur due to unawareness of the public. In a population genetic study in Alexandria, Egypt, we found that the parents of 20% of the population are first degree cousins. Out of 9,587 female cancer cases registered in the last 10 years by the Alexandria Cancer Registry, 3250 (33%) were breast cancer. Twelve percent of breast cancer patients had a positive first-degree relative family history of cancer. Familial breast cancer (FBC) occurred at a younger age, ranging from 23-74 years, with a median equal to 46.5 years compared to 35-76 years, with a median of 54.5 years, in non-familial cases. The aim of this work was to show how familial cancer registries can produce useful data, helping to develop a data base of familial cancer, for the primary care program to control the morbidity of breast cancer in females by identification of those with a positive family history of cancer who are at a high risk of developing breast cancer.
authors.affiliation: Medical Statistics Department, Medical Research Institute, Alexandria University, El-Hadara, Egypt. cmtalex@alexnet.com.eg
authors.forename: R
authors.initials: R
authors.lastname: Bedwani
authors.forename: M
authors.initials: M
authors.lastname: Abdel-Fattah
authors.forename: M
authors.initials: M
authors.lastname: El-Shazly
authors.forename: A
authors.initials: A
authors.lastname: Bassili
authors.forename: A
authors.initials: A
authors.lastname: Zaki
authors.forename: H A
authors.initials: HA
authors.lastname: Seif
authors.forename: W
authors.initials: W
authors.lastname: Weber
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D003241:Consanguinity; D003278:Contraceptives, Oral, Hormonal; D016208:Databases, Factual; D003710:Demography; D004534:Egypt / Q000453:epidemiology; D005260:Female; D006801:Humans; D007774:Lactation; D008875:Middle Aged; D009386:Neoplastic Syndromes, Hereditary / Q000453:epidemiology*; D012042:Registries; D017584:Reproductive History; D012189:Retrospective Studies; D012306:Risk
chemical_list: D003278:Contraceptives, Oral, Hormonal