title: Incidence of asthma diagnosis and self-reported allergy in relation to the school environment--a four-year follow-up study in schoolchildren.
abstract: METHODS
  In schools, the indoor air quality is often poor and there is growing concern about its impact on the pupils' health.
  
  
  OBJECTIVE
  To study the incidence of asthma diagnosis and self-reported allergy in schoolchildren in relation to the school environment.
  
  
  METHODS
  Data on asthma and allergies were collected through a postal questionnaire answered in 1993 and 1997 by 1347 (78%) pupils (initially aged 7-13 years) in 39 randomly chosen schools. Indoor pollutants were measured in about 100 classrooms in 1993 and 1995. Relationships between indoor pollutants and incidence of asthma diagnosis and self-reported allergy were studied by multiple logistic regression, adjusting for age, sex, atopy and smoking.
  
  
  RESULTS
  The incidence of asthma diagnosis was higher in pupils attending schools with more settled dust and more cat allergen (Fel d 1) in this dust. Incidence of self-reported furry pet allergy was higher in schools with more respirable particles. Among children without a history of atopy, a new asthma diagnosis was more common at higher concentrations of formaldehyde and total moulds in the classroom air.
  
  
  CONCLUSIONS
  A school environment with more dust, cat allergen, formaldehyde and moulds may affect the incidence of asthma and sensitivity to furry pets in schoolchildren.
authors.affiliation: Department of Medical Sciences/Occupational and Environmental Medicine, Uppsala University, Sweden. greta.smedje@medsci.uu.se
authors.forename: G
authors.initials: G
authors.lastname: Smedje
authors.forename: D
authors.initials: D
authors.lastname: Norbäck
mesh_terms: D000293:Adolescent; D000391:Air Microbiology; D016902:Air Pollution, Indoor / Q000009:adverse effects / Q000032:analysis*; D000485:Allergens / Q000032:analysis; D000818:Animals; D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D002415:Cats; D002648:Child; D004285:Dogs; D004391:Dust / Q000032:analysis; D005260:Female; D005557:Formaldehyde / Q000032:analysis; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D016015:Logistic Models; D008297:Male; D012574:Schools; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology
chemical_list: D000485:Allergens; D004391:Dust; D005557:Formaldehyde