Salvinorin C, a new neoclerodane diterpene from a bioactive fraction of the hallucinogenic Mexican mint Salvia divinorum.
Salvinorin C (1), a minor component from a biologically active TLC fraction, was isolated from the leaves of the Mexican mint Salvia divinorum. Its structure was elucidated on the basis of extensive proton and C-13 NMR experiments, as well as by comparison of the NMR data with those of the mono- and diacetate derivatives 5-7 of the major NaBH(4)-reduction product of salvinorin A (2). [structure: see text]
Valdés
L J
LJ
University of Michigan Hospital, Pharmacy Services, Ann Arbor, MI 48109, USA.
Chang
H M
HM
Visger
D C
DC
Koreeda
M
M
D004224:Diterpenes; D045785:Diterpenes, Clerodane; D006213:Hallucinogens / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D027544:Salvia / Q000737:chemistry*
D004224:Diterpenes; D045785:Diterpenes, Clerodane; D006213:Hallucinogens; C442894:salvinorin C