[Application of mitomycin C in glaucoma filtration surgery].
OBJECTIVE
To investigate the efficacy and the complication of glaucoma filtration surgery with intraoperative mitomycin C.


METHODS
Between April 1994 and February 1996, 33 eyes of 28 patients underwent filtration procedures with intraoperative mitomycin C. Then a follow up of mean 6.65 months (range, 1-12 months) was taken.


RESULTS
The Class I success rate was 72.7% when the intraocular pressure (IOP) was less or equal to 2.79 kPa without glaucoma medicine. The Class II success rate was 24.2% when the IOP was controlled with topical glaucoma medicine. In the postoperative period, persistant hypotony developed in 4 eyes, and hypotony-related maculopathy developed in 2 of these eyes. No conjunctival wound leak and endophthalmitis was present.


CONCLUSIONS
Intraoperative mitomycin C in glaucoma filtration surgery can increase the success rate, while it is associated with a higher incidence of complications such as hypotony.
Wu
J
J
Beijing Tongren Hospital, Beijing 100730.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D018463:Filtering Surgery; D005500:Follow-Up Studies; D015812:Glaucoma, Angle-Closure / Q000188:drug therapy* / Q000601:surgery; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000009:adverse effects / Q000627:therapeutic use*; D015814:Ocular Hypotension / Q000209:etiology
D016685:Mitomycin