title: Aortic root replacement in a patient with vancomycin-resistant Enterococcus faecium endocarditis and leukemia.
abstract: Vancomycin-resistant Enterococcus faecium endocarditis is rare and usually occurs in immunocompromised patients. We describe a patient with hairy-cell leukemia and vancomycin-resistant E faecium endocarditis. The patient presented with severe aortic insufficiency. He underwent aortic root replacement with a cryopreserved aortic homograft and was treated with a combination of quinupristin/dalfopristin, ampicillin, and gentamicin.
authors.affiliation: Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN 55902, USA.
authors.forename: I E
authors.initials: IE
authors.lastname: Konstantinov
authors.forename: K J
authors.initials: KJ
authors.lastname: Zehr
mesh_terms: D000208:Acute Disease; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000382:microbiology / Q000601:surgery*; D004697:Endocarditis, Bacterial / Q000150:complications / Q000188:drug therapy*; D016984:Enterococcus faecium / Q000187:drug effects; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000150:complications*; D008297:Male; D020713:Vancomycin Resistance