title: [Thrombosis of the abdominal aorta in a patient with nephrotic syndrome].
abstract: Nephrotic syndrome frequently causes thromboembolic complications in veins. Arterial thrombosis, however, is relatively rare. We report the case of a 47-year-old male with nephrotic syndrome complicated with abdominal aortic thrombosis. The patient complained of pain in the bilateral lower extremities 2 weeks after the development of nephrotic syndrome. The aortogram revealed complete occlusion of the abdominal aorta just below the origin of the inferior mesenteric artery. Necrosis of the legs extended rapidly, and he eventually lost his legs. Among various predisposing factors, hypercoagulability associated with nephrotic syndrome seemed to be responsible for the development of thrombosis. Thrombotic complications are sometimes serious in the nephrotic patient. Assessment for the risk factors is required to warrant prophylactic anticoagulation.
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Kanazawa Medical University, Ishikawa, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Imamura
authors.forename: M
authors.initials: M
authors.lastname: Asaka
authors.forename: A
authors.initials: A
authors.lastname: Saito
authors.forename: H
authors.initials: H
authors.lastname: Okuyama
authors.forename: M
authors.initials: M
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Nakazawa
authors.forename: N
authors.initials: N
authors.lastname: Tomosugi
authors.forename: T
authors.initials: T
authors.lastname: Yuri
authors.forename: I
authors.initials: I
authors.lastname: Ishikawa
mesh_terms: D000671:Amputation, Surgical; D001012:Aorta, Abdominal; D001018:Aortic Diseases / Q000209:etiology*; D001157:Arterial Occlusive Diseases / Q000209:etiology; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D009402:Nephrosis, Lipoid / Q000150:complications*; D019851:Thrombophilia / Q000150:complications; D013927:Thrombosis / Q000209:etiology*