title: Cell engulfment, no sooner ced than done.
abstract: Three genes, ced-2, ced-5, and ced-10, are required for both cell corpse engulfment and distal tip cell migration in C. elegans. Recently, a fourth gene, ced-12, has been identified that is required for these two processes. ced-12 encodes a novel, conserved adaptor molecule involved in the activation of Rho/Rac/CDC42-like GTPases.
authors.affiliation: Max-Planck-Institute of Neurobiology, Martinsried, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Conradt
mesh_terms: D000818:Animals; D051017:Apoptosis Regulatory Proteins; D017173:Caenorhabditis elegans; D029742:Caenorhabditis elegans Proteins; D002352:Carrier Proteins / Q000502:physiology; D003598:Cytoskeletal Proteins; D015801:Helminth Proteins / Q000502:physiology*; D008565:Membrane Proteins / Q000502:physiology*; D010587:Phagocytosis / Q000502:physiology*; D011494:Protein Kinases / Q000502:physiology*; D011518:Proto-Oncogene Proteins; D050737:Proto-Oncogene Proteins c-crk; D020744:rac GTP-Binding Proteins
chemical_list: D051017:Apoptosis Regulatory Proteins; C407268:CED-10 protein, C elegans; C438369:CED-12 protein, C elegans; C111579:CED-5 protein, C elegans; D029742:Caenorhabditis elegans Proteins; D002352:Carrier Proteins; D003598:Cytoskeletal Proteins; D015801:Helminth Proteins; D008565:Membrane Proteins; D011518:Proto-Oncogene Proteins; D050737:Proto-Oncogene Proteins c-crk; D011494:Protein Kinases; D020744:rac GTP-Binding Proteins