[Effects of intraperitoneal injection of low-dose CDDP on 3 patients with ascites owing to peritonitis carcinomatosa of gastric and colorectal carcinoma].
Three patients received intraperitoneal chemotherapy of low-dose CDDP for carcinomatous ascites due to gastric and colorectal carcinoma. Intraperitoneal injection of CDDP (30-50 mg) was given and the patients underwent systemic chemotherapy. As a result, the QOL of all patients was improved. Adverse effects of Grade 1 were observed in 1 case (nausea). This intraperitoneal chemotherapy seems to be safe and effective for ascites due to peritonitis carcinomatosa.
Kitani
K
K
Dept. of Surgery, Yao Municipal Hospital.
Morimoto
T
T
Shibata
N
N
Amano
K
K
Nakahira
S
S
Morita
S
S
Tanaka
T
T
Nomura
T
T
Okuda
H
H
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002945:Cisplatin / Q000008:administration & dosage*; D015179:Colorectal Neoplasms / Q000150:complications*; D005260:Female; D006801:Humans; D007274:Injections, Intraperitoneal; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D010538:Peritonitis / Q000188:drug therapy* / Q000209:etiology; D013274:Stomach Neoplasms / Q000150:complications*
D000970:Antineoplastic Agents; D002945:Cisplatin