title: Cationic microparticles are an effective delivery system for immune stimulatory cpG DNA.
authors.affiliation: Immunology and Infectious Diseases, Chiron Corporation, Emeryville, California 94608, USA.
authors.forename: M
authors.initials: M
authors.lastname: Singh
authors.forename: G
authors.initials: G
authors.lastname: Ott
authors.forename: J
authors.initials: J
authors.lastname: Kazzaz
authors.forename: M
authors.initials: M
authors.lastname: Ugozzoli
authors.forename: M
authors.initials: M
authors.lastname: Briones
authors.forename: J
authors.initials: J
authors.lastname: Donnelly
authors.forename: D T
authors.initials: DT
authors.lastname: O'Hagan
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage* / Q000494:pharmacology*; D000327:Adsorption; D000818:Animals; D002412:Cations; D000077286:Cetrimonium; D002593:Cetrimonium Compounds; D018899:CpG Islands; D004247:DNA / Q000008:administration & dosage* / Q000494:pharmacology*; D004337:Drug Carriers; D016503:Drug Delivery Systems; D005260:Female; D015683:Gene Products, gag / Q000276:immunology; D015488:HIV Antigens / Q000276:immunology; D015699:HIV Envelope Protein gp120 / Q000276:immunology; D015497:HIV-1 / Q000276:immunology; D007118:Immunoassay; D007273:Injections, Intramuscular; D019344:Lactic Acid; D051379:Mice; D008807:Mice, Inbred BALB C; D008863:Microspheres; D011100:Polyglycolic Acid; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers; D011498:Protein Precursors / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D002412:Cations; D002593:Cetrimonium Compounds; D004337:Drug Carriers; D015683:Gene Products, gag; D015488:HIV Antigens; D015699:HIV Envelope Protein gp120; D011108:Polymers; D011498:Protein Precursors; C059767:p55 gag precursor protein, Human immunodeficiency virus 1; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid; D004247:DNA; D000077286:Cetrimonium