Voltage-gated sodium channels.
Increased knowledge of the molecular diversity of sodium channel alpha- and beta-subunits, and their distribution of expression have been highlights of the past year. The development of subtype-specific channel blockers remains elusive, but the discovery of selective inhibitors such as mu-conotoxins promises useful antagonists in the near future.
Wood
J N
JN
Department of Biology, University College, London, UK. J.Wood@ucl.ac.uk
Baker
M
M
D000818:Animals; D006801:Humans; D015640:Ion Channel Gating / Q000187:drug effects / Q000502:physiology*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology; D015222:Sodium Channels / Q000187:drug effects / Q000502:physiology*
D015222:Sodium Channels