title: Buschke-Ollendorff syndrome--differential diagnosis of disseminated connective tissue lesions.
abstract: We report a 5-year-old boy presenting with multiple elastic type nevi and osteopoikilosis who was diagnosed as having Buschke-Ollendorff syndrome at an early age. Connective tissue lesions may present as the main symptom of varying clinical entities with different outcomes. Differential diagnosis includes papular elastorrhexis, fibroelastolytic papules of the neck, papular acne scars, and late onset focal dermal elastosis. Rare genodermatoses, i.e. Buschke-Ollendorff syndrome, pseudoxanthoma elasticum, juvenile hyaline fibromatosis and familiar cutaneous collagenoma should be carefully evaluated to provide appropriate genetic counseling and to avoid unnecessary treatment procedures.
authors.affiliation: Department of Dermatology, University Medical Center Charité, Medical Faculty of the Humboldt University, Schumannstr. 20-21, 10117 Berlin, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Assmann
authors.forename: N
authors.initials: N
authors.lastname: Mandt
authors.forename: C C
authors.initials: CC
authors.lastname: Geilen
authors.forename: U
authors.initials: U
authors.lastname: Blume-Peytavi
mesh_terms: D002675:Child, Preschool; D003240:Connective Tissue Diseases / Q000235:genetics / Q000473:pathology*; D003937:Diagnosis, Differential; D005528:Foot; D006225:Hand; D006579:Heterozygote; D006801:Humans; D008297:Male; D009506:Nevus / Q000235:genetics / Q000473:pathology*; D010023:Osteopoikilosis / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D010641:Phenotype; D011859:Radiography; D013577:Syndrome