Operational reversibility is a key aspect of carcinogenesis.
The article highlighted in this issue is "Reversibility and Persistence of Di-2-Ethylhexyl Phthalate (DEHP)- and Phenobarbital-Induced Hepatocellular Changes In Rodents," by Jason S. Isenberg, Lisa M. Kamendulis, David C. Ackley, Jacqueline H. Smith, George Pugh, Jr., Arthur W. Lington, Richard H. McKee, and James E. Klaunig (pp. 192-199).
Goodman
J I
JI
Department of Pharmacology and Toxicology, B-440 Life Sciences Building, Michigan State University, East Lansing, MI 48824, USA. goodman3@pilot.msu.edu
D000818:Animals; D002471:Cell Transformation, Neoplastic; D004051:Diethylhexyl Phthalate / Q000378:metabolism / Q000494:pharmacology*; D017629:Gap Junctions / Q000187:drug effects; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D051379:Mice; D010634:Phenobarbital / Q000494:pharmacology*
D004051:Diethylhexyl Phthalate; D010634:Phenobarbital