title: Recurrent osseous metaplasia of the cervix after loop electrosurgical excision.
abstract: BACKGROUND
  Osseous metaplasia of the uterus is a rare pathologic entity usually affecting the endometrial cavity without cervical extension. It has been reported after abortion, in cases of chronic endometritis, and as a result of metabolic disorders as hypervitaminosis D, hyperparathyroidism, hypercalcemia, and hyperphosphatemia.
  
  
  METHODS
  A woman developed osseous metaplasia of the cervix shortly after loop electrosurgical excision procedure (LEEP) for severe cervical dysplasia. Normal transvaginal ultrasonograms before the LEEP, and failure to detect osseous metaplasia after histologic review of the tissue obtained from that procedure indicate that the osseous metaplasia had been induced by the LEEP. The heterotopic bone formation rapidly recurred after initial removal. Her serum calcium, phosphorus, and vitamin D levels were normal.
  
  
  CONCLUSIONS
  LEEP may result in healing with metaplastic bone formation.
authors.affiliation: Department of Gynecology and Obstetrics, The Cleveland Clinic Foundation, Cleveland, Ohio, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Bedaiwy
authors.forename: J M
authors.initials: JM
authors.lastname: Goldberg
authors.forename: C V
authors.initials: CV
authors.lastname: Biscotti
mesh_terms: D000328:Adult; D001842:Bone and Bones; D002584:Cervix Uteri / Q000473:pathology*; D002828:Choristoma / Q000473:pathology*; D004598:Electrosurgery; D005260:Female; D006801:Humans; D008679:Metaplasia; D012008:Recurrence; D002577:Uterine Cervical Diseases / Q000473:pathology*; D002578:Uterine Cervical Dysplasia / Q000601:surgery*