title: Myocardial ischaemia in normal patients undergoing elective Caesarean section: a peripartum assessment.
abstract: Incidence rates of electrocardiographic changes during Caesarean section vary from 25 to 60%. To date, no investigator has identified myocardial ischaemia resulting from these changes. We investigated patients undergoing elective Caesarean section using peripartum Holter monitoring and serum analysis of cardiac troponin I (cTnI). Twenty-six patients presenting for elective Caesarean section were studied. Peroperative Holter monitoring continued for 12 h postoperatively, at which time blood samples for cTnI levels were taken. Significant ST changes were recorded in 42% of patients peroperatively and 38.5% of patients postoperatively. Forty-two per cent of patients experienced peroperative chest pain requiring opioid analgesia. Chest pain was significantly associated with abnormal electrocardiogram (ECG) findings. Ischaemic levels of cTnI were recorded in two patients. This study reports, for the first time, myocardial ischaemia (7.69% of patients) arising in conjunction with the ECG changes seen during elective Caesarean section. We also report episodes of significant postoperative ST-segment changes.
authors.affiliation: Department of Anaesthesia, Rotunda Hospital, Parnell Square, Dublin 1, Ireland. cdim@tesco.net
authors.forename: C
authors.initials: C
authors.lastname: Moran
authors.forename: M
authors.initials: M
authors.lastname: Ni Bhuinneain
authors.forename: M
authors.initials: M
authors.lastname: Geary
authors.forename: S
authors.initials: S
authors.lastname: Cunningham
authors.forename: P
authors.initials: P
authors.lastname: McKenna
authors.forename: J
authors.initials: J
authors.lastname: Gardiner
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D002585:Cesarean Section / Q000009:adverse effects*; D015716:Electrocardiography, Ambulatory; D005260:Female; D006339:Heart Rate; D006801:Humans; D007431:Intraoperative Complications / Q000097:blood / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D019990:Perioperative Care; D011183:Postoperative Complications / Q000097:blood / Q000503:physiopathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D019210:Troponin I / Q000097:blood
chemical_list: D015415:Biomarkers; D019210:Troponin I