title: The first total synthesis of N1999-A2: absolute stereochemistry and stereochemical implications into DNA cleavage.
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, and CREST, JST Sendai 980-8578, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Ashizawa
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Sugiura
authors.forename: M
authors.initials: M
authors.lastname: Nagaoka
authors.forename: M J
authors.initials: MJ
authors.lastname: Lear
authors.forename: M
authors.initials: M
authors.lastname: Hirama
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D004247:DNA / Q000737:chemistry / Q000187:drug effects*; D004249:DNA Damage; D053281:Enediynes; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000494:pharmacology*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D000970:Antineoplastic Agents; D053281:Enediynes; D004852:Epoxy Compounds; C437375:N1999-A2; D009281:Naphthalenes; D004247:DNA