title: Recurrent giant longitudinal duodenal ulcer with massive hemorrhage in a Helicobacter pylori-negative patient.
abstract: A 67-year-old man, in whom a linear ulcer running from the duodenal bulb to the descending part had been noted 3 years previously, was admitted to our hospital because of abdominal pain and melena. Duodenoscopy revealed a bleeding giant longitudinal ulcer, which was more extensive than before. Tests for Helicobacter pylori (Hp) were negative. The ulcer was cured by endoscopic hemostasis and repeated blood transfusions. Attention must be paid to Hp-negative post-bulbar duodenal ulcers because of the frequent complications including hemorrhage.
authors.affiliation: Department of Internal Medicine, Miyoshi Prefectural Hospital, Tokushima, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fujimoto
authors.forename: I
authors.initials: I
authors.lastname: Shimizu
authors.forename: T
authors.initials: T
authors.lastname: Horie
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: M
authors.initials: M
authors.lastname: Okazaki
authors.forename: M
authors.initials: M
authors.lastname: Niki
authors.forename: T
authors.initials: T
authors.lastname: Shiraishi
authors.forename: S
authors.initials: S
authors.lastname: Fujiwara
authors.forename: M
authors.initials: M
authors.lastname: Murata
authors.forename: K
authors.initials: K
authors.lastname: Yamamoto
authors.forename: A
authors.initials: A
authors.lastname: Iuchi
authors.forename: A
authors.initials: A
authors.lastname: Hino
authors.forename: S
authors.initials: S
authors.lastname: Ito
mesh_terms: D000368:Aged; D001528:Behcet Syndrome / Q000175:diagnosis; D001803:Blood Transfusion; D017091:Colitis, Ischemic / Q000175:diagnosis; D003424:Crohn Disease / Q000175:diagnosis; D003937:Diagnosis, Differential; D004381:Duodenal Ulcer / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D004384:Duodenoscopy; D004564:Electrocoagulation; D016481:Helicobacter Infections / Q000175:diagnosis; D016480:Helicobacter pylori; D006487:Hemostasis; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010438:Peptic Ulcer Hemorrhage / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D000077423:Polidocanol; D011092:Polyethylene Glycols / Q000627:therapeutic use; D011899:Ranitidine / Q000627:therapeutic use; D012008:Recurrence; D013274:Stomach Neoplasms / Q000175:diagnosis; D014385:Tuberculosis, Gastrointestinal / Q000150:complications; D015043:Zollinger-Ellison Syndrome / Q000175:diagnosis
chemical_list: D006635:Histamine H2 Antagonists; D000077423:Polidocanol; D011092:Polyethylene Glycols; D011899:Ranitidine