title: From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS.
authors.affiliation: Ludwig Institute for Cancer Research and Department of Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA. dcleveland@ucsd.edu
authors.forename: D W
authors.initials: DW
authors.lastname: Cleveland
authors.forename: J D
authors.initials: JD
authors.lastname: Rothstein
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics* / Q000503:physiopathology* / Q000628:therapy; D000818:Animals; D001253:Astrocytes / Q000502:physiology; D053148:Caspase 3; D020169:Caspases / Q000378:metabolism; D016923:Cell Death; D003300:Copper / Q000378:metabolism; D016228:Endothelial Growth Factors / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008222:Lymphokines / Q000235:genetics / Q000378:metabolism; D008958:Models, Molecular; D008959:Models, Neurological; D009046:Motor Neurons / Q000502:physiology*; D016900:Neurofilament Proteins / Q000235:genetics / Q000378:metabolism; D010084:Oxidation-Reduction; D017434:Protein Structure, Tertiary; D013482:Superoxide Dismutase / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D000072105:Superoxide Dismutase-1; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D015032:Zinc / Q000378:metabolism
chemical_list: D016228:Endothelial Growth Factors; D008222:Lymphokines; D016900:Neurofilament Proteins; C000606290:SOD1 protein, human; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D003300:Copper; D013482:Superoxide Dismutase; D000072105:Superoxide Dismutase-1; C505407:CASP3 protein, human; D053148:Caspase 3; D020169:Caspases; D015032:Zinc