title: Fluorinated analogues of tert-butyl alcohol as novel protecting groups for use in fluorous synthesis.
abstract: [reaction--see text] A series of fluorous derivatives of tert-butyl alcohol were prepared and evaluated as reagents for the protection of carboxylic acids for use in fluorous synthesis. Alcohol 3b can be employed efficiently to protect and immobilize medium-size nonpolar carboxylic acids in a fluorous phase.
authors.affiliation: Departamento de Química Orgánica, Facultade de Ciencias, Universidade de Santiago de Compostela, Campus Universitario, 27002 Lugo, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Pardo
authors.forename: A
authors.initials: A
authors.lastname: Cobas
authors.forename: E
authors.initials: E
authors.lastname: Guitián
authors.forename: L
authors.initials: L
authors.lastname: Castedo