A newly recognized syndrome--radiation-related bronchiolitis obliterans and organizing pneumonia. A case report and literature review.
Bronchiolitis obliterans and organizing pneumonia (BOOP) is a syndrome that has been associated with a variety of underlying disorders, including infection, collagen vascular diseases and toxic fume inhalation. Rarely, however, BOOP has been associated with radiation- or chemotherapy-induced pulmonary toxicity. Over the past 3 years, several case series have reported BOOP in the unique setting of radiation in breast cancer patients. This study describes our experience with this newly recognized syndrome and a review of the English-language literature on this syndrome.
Stover
D E
DE
Pulmonary Service, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. stoverd@mskcc.org
Milite
F
F
Zakowski
M
M
D000230:Adenocarcinoma / Q000532:radiotherapy; D001943:Breast Neoplasms / Q000532:radiotherapy; D018549:Cryptogenic Organizing Pneumonia / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000150:complications*; D011832:Radiation Injuries / Q000150:complications*; D012196:Review Literature as Topic; D013577:Syndrome; D016387:Women's Health