title: Tracheobronchial involvement with Crohn's disease.
abstract: We report the case of a young woman with Crohn's disease of the bowel who presented with a purulent tracheobronchitis and life-threatening upper airway obstruction. Fibreoptic bronchoscopy demonstrated severe tracheal and upper bronchial pseudotumours and stenosis. The role of recent discontinuation of corticosteroids, for quiescent inflammatory bowel disease, in the development of endobronchial disease and the dramatic response in airway patency after reintroduction of prednisolone in this rare complication of Crohn's disease are discussed.
authors.affiliation: Department of Respiratory Medicine, St James's University Hospital, Leeds, UK. pajo@freenetname.co.uk
authors.forename: M T
authors.initials: MT
authors.lastname: Henry
authors.forename: L A
authors.initials: LA
authors.lastname: Davidson
authors.forename: N J
authors.initials: NJ
authors.lastname: Cooke
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001991:Bronchitis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D001999:Bronchoscopy; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use; D012129:Respiratory Function Tests; D014136:Tracheitis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone