title: STR primer concordance study.
abstract: Over 1500 population database samples comprising African Americans, Caucasians, Hispanics, Native Americans, Chamorros and Filipinos were typed using the PowerPlex 16 and the Profiler Plus/COfiler kits. Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples in which a typing difference due to allele dropout was observed. At the D8S1179 locus in the population samples from Guam, there were 13 examples of allele dropout observed when using the Profiler Plus kit. The data support that the primers used in the PowerPlex 16, Profiler Plus, and COfiler kits are reliable for typing reference samples that are for use in CODIS. In addition, allele frequency databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic.
authors.affiliation: FBI, Laboratory Division, 935 Pennsylvania Avenue, NW, Washington, DC 20535, USA. bbudowle@fbi.gov
authors.forename: B
authors.initials: B
authors.lastname: Budowle
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authors.lastname: Masibay
authors.forename: S J
authors.initials: SJ
authors.lastname: Anderson
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authors.lastname: Barna
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authors.initials: L
authors.lastname: Biega
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authors.lastname: Brenneke
authors.forename: B L
authors.initials: BL
authors.lastname: Brown
authors.forename: J
authors.initials: J
authors.lastname: Cramer
authors.forename: G A
authors.initials: GA
authors.lastname: DeGroot
authors.forename: D
authors.initials: D
authors.lastname: Douglas
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authors.initials: B
authors.lastname: Duceman
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authors.initials: A
authors.lastname: Eastman
authors.forename: R
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authors.lastname: Giles
authors.forename: J
authors.initials: J
authors.lastname: Hamill
authors.forename: D J
authors.initials: DJ
authors.lastname: Haase
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authors.lastname: Janssen
authors.forename: T D
authors.initials: TD
authors.lastname: Kupferschmid
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authors.initials: T
authors.lastname: Lawton
authors.forename: C
authors.initials: C
authors.lastname: Lemire
authors.forename: B
authors.initials: B
authors.lastname: Llewellyn
authors.forename: T
authors.initials: T
authors.lastname: Moretti
authors.forename: J
authors.initials: J
authors.lastname: Neves
authors.forename: C
authors.initials: C
authors.lastname: Palaski
authors.forename: S
authors.initials: S
authors.lastname: Schueler
authors.forename: J
authors.initials: J
authors.lastname: Sgueglia
authors.forename: C
authors.initials: C
authors.lastname: Sprecher
authors.forename: C
authors.initials: C
authors.lastname: Tomsey
authors.forename: D
authors.initials: D
authors.lastname: Yet
mesh_terms: D000483:Alleles; D016208:Databases, Factual; D005554:Forensic Medicine; D005828:Genetics, Population; D006801:Humans; D044469:Racial Groups / Q000235:genetics*; D020080:Tandem Repeat Sequences; D014481:United States