title: Electromechanical assessment of left ventricular function following successful percutaneous coronary revascularization.
abstract: Percutaneous electromechanical mapping was applied to evaluate the impact of coronary revascularization on electrical and mechanical parameters in patients with prior myocardial infarction. In 15 patients with prior (> or = 4 weeks) myocardial Q-wave infarction and regional wall motion abnormalities, left ventricular endocardial mapping was performed immediately prior to percutaneous coronary revascularization. Patients underwent repetitive mapping during 6-month follow-up angiography with good revascularization results in all patients. Mean regional unipolar electrogram (UP) amplitude of all regions remained unchanged (10.4 +/- 4.2 mV prerevascularization vs. 10.2 +/- 4.4 mV postrevascularization), whereas mean local shortening (LS) of all regions increased from 6.0% +/- 5.8% to 9.7% +/- 5.3% (P < 0.001). The percentage of electromechanical match regions (LS < 6% and UP < 9 mV) remained unchanged after revascularization (15% vs. 10%; NS), whereas the percentage of mismatch regions (LS < 6% and UP > 9 mV) declined from 38% to 10% (P < 0.0001). We conclude that electromechanical mapping allows the sensitive detection of improved mechanical function after successful revascularization. Electrical activity remains unchanged 6 months after revascularization and the number of regions with an electromechanical mismatch decrease.
authors.affiliation: Department of Cardiology, Medizinische Klinik I, University Hospital, RWTH Aachen, Germany.
authors.forename: K C
authors.initials: KC
authors.lastname: Koch
authors.forename: M
authors.initials: M
authors.lastname: Wenderdel
authors.forename: C
authors.initials: C
authors.lastname: Stellbrink
authors.forename: P
authors.initials: P
authors.lastname: Hanrath
authors.forename: J
authors.initials: J
authors.lastname: vom Dahl
mesh_terms: D000368:Aged; D018780:Body Surface Potential Mapping; D004594:Electrophysiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000601:surgery; D009204:Myocardial Revascularization; D016277:Ventricular Function, Left / Q000502:physiology*