Moderate alcohol consumption and waiting time to pregnancy.
BACKGROUND
Recent research indicates that even a moderate consumption of alcohol in women trying to become pregnant is associated with longer waiting time to pregnancy. The findings, though, are based upon few observations.


METHODS
Self-reported data on alcohol intake and waiting time to pregnancy (0-2, 3-5, 6-12 and >12 months) was used for 39 612 pregnant women, recruited to the Danish National Birth Cohort within the first 24 weeks of pregnancy from 1997 to 2000. Main outcome measures were odds ratios (OR) for a prolonged waiting time to pregnancy according to alcohol intake.


RESULTS
In nulliparous women neither moderate nor high alcohol intake was related with longer waiting time to pregnancy compared with a low intake. In parous women, a modest association was seen only among those with an intake of >14 drinks per week (subfecundity OR 1.3; 95% confidence interval 1.0-1.7). Women who reported no alcohol intake had a slightly longer waiting time (subfecundity OR 1.2; 95% confidence interval 1.1-1.3) than women with a moderate intake of alcohol.


CONCLUSIONS
Our findings do not corroborate recent results suggesting a marked reduction in fecundity associated with a moderate intake of alcohol.
Juhl
M
M
Danish Epidemiology Science Centre at the Department of Epidemiology Research, Statens Serum Institut, 5, Artillerivej, DK-2300 Copenhagen S, Denmark. mju@ssi.dk
Nyboe Andersen
A M
AM
Grønbaek
M
M
Olsen
J
J
D000328:Adult; D000367:Age Factors; D000428:Alcohol Drinking / Q000009:adverse effects*; D015331:Cohort Studies; D003718:Denmark; D005260:Female; D005298:Fertility; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D009765:Obesity / Q000150:complications; D016017:Odds Ratio; D010298:Parity; D011247:Pregnancy; D012907:Smoking / Q000009:adverse effects; D013997:Time Factors