[Optimization of oxygen transport with perfluorane emulsion during surgery of lung cancer].
Perfluorane emulsion was included in infusion/transfusion therapy for optimization of oxygen transport. Central hemodynamics was analyzed during the intervention and immediate postoperative period in 80 patients operated on for lung cancer (pneumonectomy, lobectomy, bilobectomy) under conditions of one-lung ventilation. In the control group perfluorane (6 ml/kg) was infused during induction anesthesia. Increased oxygen delivery without increase of cardiac index was observed in the patients treated with perfluorane. Perfluorane had a positive impact on total peripheral resistance during and immediately after the intervention and virtually did not affect other central hemodynamic parameters. Addition of perfluorane to intraoperative infusion therapy improved oxygen budget of operated cancer patients with concomitant therapeutic diseases.
Biriukov
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Petrova
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D000368:Aged; D000768:Anesthesia, General; D001802:Blood Substitutes / Q000008:administration & dosage*; D004655:Emulsions; D005466:Fluorocarbons / Q000008:administration & dosage*; D006438:Hemodilution; D006439:Hemodynamics; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D011013:Pneumonectomy; D012121:Respiration, Artificial
D001802:Blood Substitutes; D004655:Emulsions; D005466:Fluorocarbons; D010100:Oxygen