title: NUREBASE: database of nuclear hormone receptors.
abstract: Nuclear hormone receptors are an abundant class of ligand activated transcriptional regulators, found in varying numbers in all animals. Based on our experience of managing the official nomenclature of nuclear receptors, we have developed NUREBASE, a database containing protein and DNA sequences, reviewed protein alignments and phylogenies, taxonomy and annotations for all nuclear receptors. The reviewed NUREBASE is completed by NUREBASE_DAILY, automatically updated every 24 h. Both databases are organized under a client/server architecture, with a client written in Java which runs on any platform. This client, named FamFetch, integrates a graphical interface allowing selection of families, and manipulation of phylogenies and alignments. NUREBASE sequence data is also accessible through a World Wide Web server, allowing complex queries. All information on accessing and installing NUREBASE may be found at http://www.ens-lyon.fr/LBMC/laudet/nurebase.html.
authors.affiliation: Laboratoire de Biologie Moléculaire et Cellulaire, CNRS UMR 5665, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France.
authors.forename: Jorge
authors.initials: J
authors.lastname: Duarte
authors.forename: Guy
authors.initials: G
authors.lastname: Perrière
authors.forename: Vincent
authors.initials: V
authors.lastname: Laudet
authors.forename: Marc
authors.initials: M
authors.lastname: Robinson-Rechavi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003628:Database Management Systems; D030562:Databases, Protein; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D008024:Ligands; D010802:Phylogeny; D017434:Protein Structure, Tertiary; D018160:Receptors, Cytoplasmic and Nuclear / Q000737:chemistry / Q000235:genetics*; D016415:Sequence Alignment; D018511:Systems Integration; D009626:Terminology as Topic
chemical_list: D008024:Ligands; D018160:Receptors, Cytoplasmic and Nuclear