title: A huge abdominal mass mimicking ovarian cancer: p53-negative but aneuploid myxoid leiomyosarcoma of the uterus.
abstract: OBJECTIVE
  Less than 20 myxoid leiomyosarcoma cases were reported in literature. Since, these tumors are very rare and may exhibit highly malignant behavior despite their low mitotic index, clinical course and optimum type of therapy of myxoid variant of leiomyosarcoma were not well understood. The goal of this report is to contribute the better understanding of this rare type of tumor.
  
  
  METHODS
  A 39-year-old woman presented with a huge abdominal cystic mass. Laparotomy was performed and frozen section diagnosis was low-grade uterine leiomyosarcoma. TAH-BSO, omentectomy, pelvic lymph node and peritoneal samplings were carried out. No chemotherapy was performed after surgical therapy.
  
  
  RESULTS
  Final histopathological diagnosis was uterine myxoid leiomyosarcoma. The tumor was p53-negative and had aneuploid DNA content. The patient tolerated well the operation and she is alive and free of disease after 24 months of primary surgical treatment.
  
  
  CONCLUSIONS
  Uterine myxoid leiomyosarcoma may present a huge abdominal cystic mass and can be treated successfully with surgery alone.
authors.affiliation: Department of Obstetrics and Gynecology, Cerrahpapa Medical School, Ystanbul University, P.O. Box 11, Cerrahpapa, Fatih, Ystanbul, Turkey. semihkaleli@yahoo.com
authors.forename: S
authors.initials: S
authors.lastname: Kaleli
authors.forename: Z
authors.initials: Z
authors.lastname: Calay
authors.forename: N
authors.initials: N
authors.lastname: Ceydeli
authors.forename: K
authors.initials: K
authors.lastname: Aydýnlý
authors.forename: D
authors.initials: D
authors.lastname: Kösebay
mesh_terms: D000328:Adult; D000782:Aneuploidy; D004247:DNA / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007889:Leiomyoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010051:Ovarian Neoplasms; D016159:Tumor Suppressor Protein p53 / Q000032:analysis*; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
chemical_list: D016159:Tumor Suppressor Protein p53; D004247:DNA