title: Evidence for excess long-term mortality after treated subarachnoid hemorrhage.
abstract: OBJECTIVE
  The purpose of this study was to examine the long-term mortality rate of patients with aneurysmal subarachnoid hemorrhage (SAH) compared with that of the general population.
  
  
  METHODS
  Aneurysmal SAH patients who were treated for ruptured aneurysm from 1977 through 1998 in a tertiary referral center (n=1537) were followed up for a median of 7.5 years. Dates and causes of death were determined. Standardized mortality ratios (observed/expected deaths) according to age, sex, and Glasgow Outcome Scale at 12 months after surgery were calculated.
  
  
  RESULTS
  The mortality rate among patients with good recovery at 12 months was twice that of the general population. The excess mortality appeared to be most evident in younger age groups. Cerebrovascular and cardiovascular diseases were the principal causes of premature death. The result was similar among patients without preexisting cardiovascular diseases at the time of SAH.
  
  
  CONCLUSIONS
  Aneurysmal SAH patients have an excess mortality rate even after successful treatment of ruptured aneurysms. Therefore, aneurysmal SAH should be viewed more as one aspect of a chronic general vascular disease, and more attention should be given to treatment of risk factors and long-term follow-up of these patients.
authors.affiliation: Department of Neurosurgery, University Hospital of Kuopio, Kuopio, Finland. antti.ronkainen@kuh.fi
authors.forename: A
authors.initials: A
authors.lastname: Ronkainen
authors.forename: M
authors.initials: M
authors.lastname: Niskanen
authors.forename: J
authors.initials: J
authors.lastname: Rinne
authors.forename: T
authors.initials: T
authors.lastname: Koivisto
authors.forename: J
authors.initials: J
authors.lastname: Hernesniemi
authors.forename: M
authors.initials: M
authors.lastname: Vapalahti
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003710:Demography; D005260:Female; D005387:Finland / Q000453:epidemiology; D005500:Follow-Up Studies; D023261:Glasgow Outcome Scale / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D017678:Sex Distribution; D013345:Subarachnoid Hemorrhage / Q000401:mortality* / Q000628:therapy*; D015996:Survival Rate; D013995:Time; D016896:Treatment Outcome; D014505:Urban Population