Alternariosis after liver transplantation.
Alternaria is a saprophytic fungus that is increasingly recognized as a human pathogen, particularly in immunocompromised hosts, including solid-organ transplant recipients. Although combined surgical and medical treatment seem to be useful in the management of this infection, an optimal antifungal therapy remains to be defined. Only four cases of alternariosis after orthotopic liver transplantation have been reported. We describe an additional case and review the literature on infections due to Alternaria in organ transplant recipients, with special emphasis on treatment.
Benito
N
N
Institut Clínic d' Infeccions i Inmunologia, IDIBAPS, Hospital Clínic, Universitat de Barcelona, Spain. nbenito@clinic.ub.es
Moreno
A
A
Puig
J
J
Rimola
A
A
D000528:Alternaria; D000935:Antifungal Agents / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D017964:Itraconazole / Q000627:therapeutic use; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D016559:Tacrolimus / Q000009:adverse effects
D000935:Antifungal Agents; D007166:Immunosuppressive Agents; D017964:Itraconazole; D016559:Tacrolimus