title: Polyvalent contact allergy to corticosteroids: a report of two cases.
abstract: Two cases of positive allergic reactions to eight patch-tested corticosteroid substances are reported. The patients were middle-aged women with a long history of contact dermatitis who had used topical corticosteroids for years. Pure corticosteroid substances were tested in therapeutic and 1% concentrations in ethanol and petrolatum. The intensity of reactions was different depending on the vehicle and concentration. Patients with hypersensitivity to several corticosteroid substances represent an important therapeutic problem.
authors.affiliation: Department of Dermatology, St Anne's, Hospital, Masaryk University, Brno, Czech Republic. sekr.dvk@fnusa.cz
authors.forename: V
authors.initials: V
authors.lastname: Semrádová
authors.forename: E
authors.initials: E
authors.lastname: Dastychová
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D003429:Cross Reactions; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D003879:Dermatologic Agents / Q000009:adverse effects*; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D010328:Patch Tests
chemical_list: D000893:Anti-Inflammatory Agents; D003879:Dermatologic Agents; D005938:Glucocorticoids