title: Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus.
abstract: The authors describe the outcome of five patients with a cardiac thrombus selected among 183 patients with stroke (2.7 %) who were given IV tissue plasminogen activator (tPA). No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moderate outcome. One patient had late recurrent cerebral embolism and died. These data suggest that the presence of a cardiac thrombus is not associated with a high risk of recurrent embolism in patients with stroke who are given IV tPA.
authors.affiliation: Service d'Urgences Neurovasculaires, Hôpital Neurologique, Lyon, France. lderex@yahoo.com
authors.forename: L
authors.initials: L
authors.lastname: Derex
authors.forename: N
authors.initials: N
authors.lastname: Nighoghossian
authors.forename: M
authors.initials: M
authors.lastname: Perinetti
authors.forename: J
authors.initials: J
authors.lastname: Honnorat
authors.forename: P
authors.initials: P
authors.lastname: Trouillas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000075202:Contraindications; D005260:Female; D006325:Heart Atria; D006352:Heart Ventricles; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000188:drug therapy*; D007262:Infusions, Intravenous; D020766:Intracranial Embolism / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
chemical_list: D010959:Tissue Plasminogen Activator