title: Acquired Robertsonian translocations in two leukemia patients.
abstract: Robertsonian translocations were observed in two leukemia patients. The first case was a patient with chronic lymphocytic leukemia, who was found to have a rare Robertsonian translocation der(14;15)(q10;q10). The second case, a patient with acute myeloid leukemia, had multiple Robertsonian translocations: der(15)t(13;15)(q11.1;p11.1), der(14;22)(q10;q10), and dic(21;22)(p11.1;p11.1). Acquired multiple Robertsonian translocations have not been reported previously in leukemia.
authors.affiliation: Department of Biochemistry, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA.
authors.forename: D
authors.initials: D
authors.lastname: Chinnappan
authors.forename: A
authors.initials: A
authors.lastname: Philip
authors.forename: X
authors.initials: X
authors.lastname: Wu
authors.forename: A
authors.initials: A
authors.lastname: Pan
authors.forename: H E
authors.initials: HE
authors.lastname: Wyandt
mesh_terms: D000208:Acute Disease; D000368:Aged; D002882:Chromosomes, Human, Pair 13; D002883:Chromosomes, Human, Pair 14; D002884:Chromosomes, Human, Pair 15; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics*; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D014178:Translocation, Genetic