title: Visualization of inner ear dysplasias in patients with sensorineural hearing loss.
abstract: OBJECTIVE
  We evaluated a data acquisition and post-processing protocol for inner ear (IE) assessment by MR imaging in patients, suffering from various labyrinth malformations.
  
  
  METHODS
  MR IE studies of 158 consecutive patients (316 IEs) suffering from sensorineural hearing loss without evidence of an acoustic neurinoma were reviewed for pathologies of the IE and internal acoustic meatus. High-resolution MR data of all abnormal IE studies (n=45) were post-processed to previously standardized 3D volume rendered (VR) reconstructions.
  
  
  RESULTS
  In 9 patients (5.7%) the following IE dysplasias were detected: malformation of the cochlea (6 IEs), vestibulum (4 IEs), semicircular canals (12 IEs) and vestibular aqueduct/endolymphatic sac (10 IEs). One patient showed evidence of an aplasia of the vestibulocochlear nerve. In 4 patients multiple IE dysplasias were encountered. Comprehensive 3D visualization of all labyrinthine dysplasias was achieved by the use of two VR reconstructions. The overall time for bilateral IE assessment amounted to 30-35 min.
  
  
  CONCLUSIONS
  The imaging protocol allows for rapid and comprehensive visualization of various IE dysplasias, based on a limited number of VR reconstructions.
authors.affiliation: Neuroradiology Section, Department of Radiology, Charité Campus Mitte, Humboldt University, Berlin, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Klingebiel
authors.forename: U
authors.initials: U
authors.lastname: Bockmühl
authors.forename: M
authors.initials: M
authors.lastname: Werbs
authors.forename: B
authors.initials: B
authors.lastname: Freigang
authors.forename: W
authors.initials: W
authors.lastname: Vorwerk
authors.forename: N
authors.initials: N
authors.lastname: Thieme
authors.forename: R
authors.initials: R
authors.lastname: Lehmann
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D007758:Ear, Inner / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology*; D005069:Evaluation Studies as Topic; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007759:Labyrinth Diseases / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography; D015203:Reproducibility of Results; D013997:Time Factors