title: A bold new direction for environmental health research.
abstract: The biotechnology revolution has opened new opportunities for addressing current inadequacies in decision making regarding environmental health. Strategic investments need to be made (1) to develop high-throughput technologies that could accelerate toxicity testing and generate a mechanistic understanding of toxicity, (2) to incorporate individual susceptibility into risk assessments, and (3) to establish a rational basis for testing and regulatory decision making. New initiatives of the National Institute of Environmental Health Sciences, including the Environmental Genome Project and the Toxicogenomics Center, are discussed.
authors.affiliation: National Institute of Environmental Health Sciences and the National Toxicology Program, Research Triangle Park, NC, USA. olden@niehs.nih.gov
authors.forename: K
authors.initials: K
authors.lastname: Olden
authors.forename: J
authors.initials: J
authors.lastname: Guthrie
authors.forename: S
authors.initials: S
authors.lastname: Newton
mesh_terms: D003657:Decision Making; D004782:Environmental Health / Q000639:trends*; D006291:Health Policy; D006801:Humans; D009152:Mutagenicity Tests / Q000379:methods; D012107:Research Design; D018570:Risk Assessment; D014481:United States