title: Tissue-specific expression of the Ets gene Xsap-1 during Xenopus laevis development.
abstract: We report the cloning of Xenopus laevis Xsap-1 cDNA, encoding a member of the ternary complex factor subfamily of ETS transcription factors. The expression pattern of Xsap-1 was examined during Xenopus embryogenesis using whole-mount in situ hybridization. Spatial expression of Xsap-1 mRNA is first detected at the animal pole at the mid-blastula stage. During neurulation Xsap-1 is expressed in cells participating in neural tube formation, in the sensorial layer of the epidermal ectoderm, and in an anterior region of the ventral mesoderm. Later, Xsap-1 expression is observed in the eye, ear vesicle, branchial arches, heart, pronephros, in the somites, and the developing nervous system, such as fore-, mid-, and hindbrain as well as in the cranial ganglion X.
authors.affiliation: Institut für Zellbiologie, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Nentwich
authors.forename: F E
authors.initials: FE
authors.lastname: Münchberg
authors.forename: G
authors.initials: G
authors.lastname: Frommer
authors.forename: A
authors.initials: A
authors.lastname: Nordheim
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D018076:DNA, Complementary / Q000378:metabolism; D004475:Ectoderm / Q000378:metabolism; D017403:In Situ Hybridization; D020935:MAP Kinase Signaling System; D008648:Mesoderm / Q000378:metabolism; D008969:Molecular Sequence Data; D009432:Neural Crest / Q000196:embryology; D009474:Neurons / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000096:biosynthesis* / Q000235:genetics; D050783:Proto-Oncogene Proteins c-ets; D020133:Reverse Transcriptase Polymerase Chain Reaction; D026362:Serum Response Factor / Q000378:metabolism; D013997:Time Factors; D014157:Transcription Factors / Q000096:biosynthesis* / Q000235:genetics; D029867:Xenopus Proteins / Q000096:biosynthesis* / Q000235:genetics; D014982:Xenopus laevis
chemical_list: D018076:DNA, Complementary; D011518:Proto-Oncogene Proteins; D050783:Proto-Oncogene Proteins c-ets; D026362:Serum Response Factor; D014157:Transcription Factors; D029867:Xenopus Proteins; C449813:Xsap-1 protein, Xenopus