Influence of endurance running and recovery diet on intramyocellular lipid content in women: a 1H NMR study.
Using a randomly assigned crossover design, we evaluated the change in intramyocellular lipid stores (IMCL) from baseline after a 2-h treadmill run [67% of maximal oxygen uptake (VO2 max)] and the recovery of IMCL in response to a postexercise very low-fat (10% of energy, LFAT) or moderate-fat (35% of energy, MFAT) recovery diet in seven female runners. IMCL was measured in soleus muscle by use of water-suppressed 1H-NMR spectroscopic imaging before (baseline), after, and approximately 22 h and 70 h after the run. IMCL fell by approximately 25% (P < 0.05) during the endurance run and was dependent on dietary fat content for postexercise recovery (P = 0.038, diet x time interaction). Consumption of the MFAT recovery diet allowed IMCL stores to return to baseline by 22 h and to overshoot (vs. baseline) by 70 h postexercise. In contrast, consumption of the LFAT recovery diet did not allow IMCL stores to return to baseline even by 70 h after the endurance run (P < 0.01 at 70 h). These results suggest that a certain quantity of dietary fat is required to replenish IMCL after endurance running.
Larson-Meyer
D Enette
DE
Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana 70808, USA. larsonde@pbrc.edu
Newcomer
Bradley R
BR
Hunter
Gary R
GR
D000328:Adult; D001769:Blood / Q000378:metabolism; D001853:Bone Marrow / Q000378:metabolism; D018592:Cross-Over Studies; D018752:Diet, Fat-Restricted; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D050356:Lipid Metabolism; D009682:Magnetic Resonance Spectroscopy; D018482:Muscle, Skeletal / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D010807:Physical Endurance; D011522:Protons; D012420:Running / Q000502:physiology*; D016037:Single-Blind Method; D013997:Time Factors
D006728:Hormones; D011522:Protons