Prevalence of human papillomavirus in elderly women with cervical cancer.
To investigate the relation between the prevalence of human papillomavirus (HPV) and age in cervical cancer patients, material from 93 patients with Ia-IIb cervical carcinoma was analyzed for the presence of HPV by both type-specific and general primer polymerase chain reaction. Patients were divided into 2 groups: 64 years or younger, and 65 years and older. There was no statistically significant difference in either the prevalence of HPV DNA or distribution of genotypes amongst the 2 groups. Therefore, HPV detection can be equally well used in the management and follow-up of elderly cervical cancer patients.
Baay
M F
MF
Department of Medical Oncology, University of Antwerp, Wilrijk, Belgium. Marc.Baay@uia.ua.ac.be
Tjalma
W A
WA
Weyler
J
J
Pattyn
G G
GG
Lambrechts
H A
HA
Goovaerts
G
G
Baekelandt
M
M
Buytaert
P
P
Van Marck
E A
EA
Lardon
F
F
Vermorken
J B
JB
D000368:Aged; D000375:Aging; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D027383:Papillomaviridae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery / Q000821:virology*
D004279:DNA, Viral