Regulating microtubule properties by modifying their organizing minus ends.
In the November 2001 issue of Developmental Cell, Vogel et al. describe that the budding yeast gamma-tubulin, Tub4p, is phosphorylated at a conserved tyrosine in G1 phase of the cell cycle. The results suggest that gamma-tubulin phosphorylation regulates the number and dynamics of microtubules.
Usui
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The Beatson Institute for Cancer Research, CRC Beatson Laboratories, G61 1BD, Glasgow, United Kingdom.
Schiebel
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D002453:Cell Cycle / Q000502:physiology; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D022101:Microtubule-Organizing Center / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism*; D010766:Phosphorylation; D029701:Saccharomyces cerevisiae Proteins; D014404:Tubulin / Q000235:genetics / Q000378:metabolism*
D005656:Fungal Proteins; D029701:Saccharomyces cerevisiae Proteins; C100764:TUB4 protein, S cerevisiae; D014404:Tubulin