Cytomegalovirus pneumonia: high-resolution CT findings in ten non-AIDS immunocompromised patients.
OBJECTIVE
To describe the HRCT findings of cytomegalovirus (CMV) pneumonia in non-AIDS immunocompromised patients


METHODS
This retrospective study involved the ten all non-AIDS immunocompromised patients with biopsy-proven CMV pneumonia and without other pulmonary infection encountered at our Medical Center between January 1997 and May 1999. HRCT scans were retrospectively analysed by two chest radiologists and decisions regarding the findings were reached by consensus.


RESULTS
The most frequent CT pattern was ground-glass opacity, seen in all patients, with bilateral patchy (n = 8) and diffuse (n = 2) distribution. Other findings included poorly-defined small nodules (n = 9) and consolidation (n = 7). There was no zonal predominance. The small nodules, bilateral in eight cases and unilateral in one, were all located in the centrilobular region. Consolidation (n = 7), with patchy distribution, was bilateral in five of seven patients (71%). Pleural effusion and bilateral areas of thickened interlobular septa were seen in six patients (60%).


CONCLUSIONS
CMV pneumonia in non-AIDS immunocompromised patients appears on HRCT scans as bilateral mixed areas of ground-glass opacity, poorly defined centrilobular small nodules, and consolidation. Interlobular septal thickening and pleural effusion are frequently associated.
Moon
J H
JH
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. kslee@smc.samsung.co.kr
Kim
E A
EA
Lee
K S
KS
Kim
T S
TS
Jung
K J
KJ
Song
J H
JH
D003586:Cytomegalovirus Infections / Q000000981:diagnostic imaging* / Q000276:immunology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000000981:diagnostic imaging* / Q000276:immunology / Q000821:virology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*