Asymmetric induction in the 1,3-dipolar cycloaddition of chiral nitrile oxide derived from (2R)-bornane-10,2-sultam.
The efficient preparation of the chiral nitrile oxide derived from N-glyoxyloyl-(2R)-bornane-10,2-sultam is presented. The nitrile oxide was trapped in situ with substituted olefins as dipolarophiles to furnish optically active 2-isoxazolines.
Jóźwik
J
J
Department of Chemistry, University of Warsaw, Warsaw, Poland.
Kosior
M
M
Kiegiel
J
J
Jurczak
J
J