title: Water or antiseptic for periurethral cleaning before urinary catheterization: a randomized controlled trial.
abstract: BACKGROUND
  Despite a lack of empiric data to support the practice, traditionally, antiseptic solutions have been used to clean the periurethral area before inserting an indwelling catheter. The purpose of this study was to compare urinary colonization rates of subjects whose periurethral area was cleaned with water versus chlorhexidine 0.1% before the insertion of an indwelling urinary catheter.
  
  
  METHODS
  Obstetric patients who required urinary catheterization as part of their routine care were randomly assigned to either the "water" or "chlorhexidine" group with a sealed envelope. A sterile specimen of urine was collected 24 hours after insertion of the catheter.
  
  
  RESULTS
  Of the 436 patients (86.2%) with complete data (water group, 219; antiseptic group, 217), 38 (8.7%) had urinary tract bacteriuria >10(6) cfu/L. Rates of urinary tract infection were similar in each group (water group, 8.2%; antiseptic group, 9.2%; odds ratio 1.13; 95% confidence interval 0.58-2.21).
  
  
  CONCLUSIONS
  The practice of periurethral cleaning with an antiseptic did not decrease the rates of bacteriuria in this population and is probably not useful.
authors.affiliation: Nursing and Women's Health Research Centre, Royal Brisbane Hospital, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Webster
authors.forename: R H
authors.initials: RH
authors.lastname: Hood
authors.forename: C A
authors.initials: CA
authors.lastname: Burridge
authors.forename: M L
authors.initials: ML
authors.lastname: Doidge
authors.forename: K M
authors.initials: KM
authors.lastname: Phillips
authors.forename: N
authors.initials: N
authors.lastname: George
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D004203:Disinfection / Q000379:methods*; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D011247:Pregnancy; D014521:Urethra / Q000382:microbiology*; D014546:Urinary Catheterization / Q000379:methods*; D014867:Water
chemical_list: D000891:Anti-Infective Agents, Local; D014867:Water; C010882:chlorhexidine gluconate; D002710:Chlorhexidine