title: The cause and natural history of isolated urinary retention in young women.
abstract: OBJECTIVE
  Using a questionnaire mailed to patients we evaluated the course and natural history of urinary retention in women, of which the cause is attributed to electromyography abnormality of the striated urethral sphincter. Previously urinary retention in young women has often been considered to be due to multiple sclerosis or a manifestation of a psychogenic disorder.
  
  
  METHODS
  A questionnaire was mailed to 216 women with abnormal sphincter electromyography and urinary retention. Of the 112 responses we analyzed the 91 from those who had been in complete urinary retention.
  
  
  RESULTS
  Mean patient age at the onset of complete retention was 27.7 years (range 10 to 50). No patients had neurological features indicating a cauda equina lesion or central demyelination and none had progressed to features of a general neurological disorder. Mean maximum bladder capacity at the initial episode of complete retention was 1,208 ml. Of the women 65% reported an event that had apparently precipitated urinary retention, most commonly a gynecologic surgical procedure using general anesthesia. Sacral neuromodulation was the only therapeutic intervention that restored voiding.
  
  
  CONCLUSIONS
  The concept of an organic cause of urinary retention in otherwise healthy young women has considerable importance in terms of correct management. Neurological investigation in these women does not reveal underlying neurological disease. It is thought that this disorder is due to a primary failure of relaxation of the striated urethral sphincter.
authors.affiliation: Department of Uro-Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Swinn
authors.forename: Oliver J
authors.initials: OJ
authors.lastname: Wiseman
authors.forename: Eithne
authors.initials: E
authors.lastname: Lowe
authors.forename: Clare J
authors.initials: CJ
authors.lastname: Fowler
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D004576:Electromyography; D005260:Female; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D011795:Surveys and Questionnaires; D014521:Urethra / Q000503:physiopathology; D016055:Urinary Retention / Q000209:etiology* / Q000503:physiopathology