title: Haemolytic anaemia after oral self-giving of naphthalene-containing oil.
abstract: A clinical case of suicide attempt by means of oral self-giving of naphthalene-containing oil in an old man was reported. Clinical features showed haemolytic anaemia supported by a decrease of haemoglobin concentration and red blood cell count, an increase of bilirubin (prevalently indirect) and lactate dehydrogenase and very low levels of haptoglobin. Methaemoglobin (metHb) measured at admission to the Emergency Room and 19 days after poisoning was still above normal limits. No deficiency of glucose-6-phosphate dehydrogenase was detected. The clinical manifestations ameliorated after treatment with concentrated red blood cells and ascorbic acid, with fast normalization of metHb. The clinical picture appeared almost normal 1 month after poisoning. The clinical diagnosis was 'haemolytic anaemia caused by naphthalene'. Absence of glucose-6-phosphate dehydrogenase deficiency probably reduced the severity of poisoning.
authors.affiliation: Department of Environmental Medicine and Public Health, University of Padova, Via Giustiniani 2, 35128 Padova, Italy. andrea@trevisan.unipd.it
authors.forename: A
authors.initials: A
authors.lastname: Trevisan
authors.forename: M
authors.initials: M
authors.lastname: Rossi di Schio
authors.forename: M
authors.initials: M
authors.lastname: Pieno
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000743:Anemia, Hemolytic / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy; D001205:Ascorbic Acid / Q000627:therapeutic use; D001663:Bilirubin / Q000097:blood; D004906:Erythrocyte Count; D017707:Erythrocyte Transfusion; D006801:Humans; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced / Q000473:pathology; D009281:Naphthalenes / Q000008:administration & dosage / Q000506:poisoning*; D009821:Oils; D013406:Suicide, Attempted
chemical_list: D009281:Naphthalenes; D009821:Oils; C031721:naphthalene; D001205:Ascorbic Acid; D001663:Bilirubin