title: The use of contrast-enhanced color Doppler ultrasound in the differentiation of retinal detachment from vitreous membrane.
abstract: OBJECTIVE
  To compare the clinical utility of contrast-enhanced color Doppler US in the differentiation of retinal detachment (RD) from vitreous membrane (VM) with that of various conventional US modalities, and to analyze the enhancement patterns in cases showing an enhancement effect.
  
  
  METHODS
  In 32 eyes examined over a recent two-year period, RD (n=14) and VM (n=18) were confirmed by surgery (n=28) or clinical follow-up (n=4). In all cases, gray-scale, color Doppler, and power Doppler US were performed prior to contrast injection, and after the intravenous injection of Levovist (Schering, Berlin) by hand for 30 seconds at a dose of 2.5 g and a concentration of 300 mg/mL via an antecubital vein, contrast-enhanced color Doppler US was performed. At Doppler US, the diagnostic criterion for RD and VM was whether or not color signals were visualized in membranous structures.
  
  
  RESULTS
  Diagnostic accuracy was 78% at gray-scale US, 81% at color Doppler US, 59% at power Doppler US, and 97% at contrast-enhanced color Doppler US. The sensitivity of color Doppler US to color signals in RD increased from 57% to 93% after contrast enhancement. The enhancement patterns observed were signal accentuation (n=3), signal extension (n=2), signal addition (n=3), and new signal visualization (n=5).
  
  
  CONCLUSIONS
  Contrast-enhanced color Doppler US was the most accurate US modality for differentiating RD from VM, showing a significantly increased signal detection rate in RD.
authors.affiliation: Department of Radiology, Busan Paik Hospital College of Medicine, Inje University, Busan, Korea. hancholi@chollian.net
authors.forename: S S
authors.initials: SS
authors.lastname: Han
authors.forename: S K
authors.initials: SK
authors.lastname: Chang
authors.forename: J H
authors.initials: JH
authors.lastname: Yoon
authors.forename: Y J
authors.initials: YJ
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides / Q000008:administration & dosage; D012163:Retinal Detachment / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color / Q000379:methods*; D020255:Vitreous Detachment / Q000000981:diagnostic imaging*
chemical_list: D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508