title: JSNP: a database of common gene variations in the Japanese population.
abstract: JSNP is a repository of Japanese Single Nucleotide Polymorphism (SNP) data, begun in 2000 and developed through the Prime Minister's Millennium Project. The aim of this undertaking is to identify and collate up to 150 000 SNPs from the Japanese population, located in genes or in adjacent regions that might influence the coding sequence of the genes. The project has been carried out by a collaboration between the Human Genome Center (HGC) in the Institute of Medical Science (IMS) at the University of Tokyo and the Japan Science and Technology Corporation (JST). JSNP serves as both a storage site for the Japanese SNPs obtained from the ongoing project and as a facility for public dissemination to allow researchers access to high quality SNP data. A primary motivation of the project is the construction of a basic data set to identify relationships between polymorphisms and common diseases or the reaction to drugs. As such, emphasis has been placed on the identification of SNPs that lie in candidate regions which may affect phenotype but which would not necessarily directly cause disease. Unrestricted access to JSNP and any associated files is available at http://snp.ims.u-tokyo.ac.jp/.
authors.affiliation: Bioinformatics Division, Japan Science and Technology Corporation (JST), 5-3 Yonban-cho, Chiyoda-ku, Tokyo 102-0081, Japan.
authors.forename: Mika
authors.initials: M
authors.lastname: Hirakawa
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Tanaka
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Masako
authors.initials: M
authors.lastname: Kuroda
authors.forename: Toshihisa
authors.initials: T
authors.lastname: Takagi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakamura
mesh_terms: D002877:Chromosomes, Human; D003196:Computer Graphics; D003628:Database Management Systems; D030541:Databases, Genetic; D064420:Drug-Related Side Effects and Adverse Reactions; D005544:Forecasting; D030342:Genetic Diseases, Inborn / Q000235:genetics; D014644:Genetic Variation; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D007564:Japan; D020641:Polymorphism, Single Nucleotide