title: Bioactive steroidal alkaloid glycosides from Solanum aculeastrum.
abstract: Solanum aculeastrum Dunal was investigated for the presence of molluscicidal compounds. This led to the isolation of solaculine A, from the root bark in addition to known steroidal alkaloids; solamargine and beta-solamarine from the berries. The structures were elucidated by spectroscopic techniques. Molluscicidal activity of the aqueous extracts of the berries and root bark, and the isolated compounds were investigated.
authors.affiliation: Chemistry Department, Kenyatta University, PO Box 43844, Nairobi, Kenya.
authors.forename: Alphonse W
authors.initials: AW
authors.lastname: Wanyonyi
authors.forename: Sumesh C
authors.initials: SC
authors.lastname: Chhabra
authors.forename: Gerald
authors.initials: G
authors.lastname: Mkoji
authors.forename: Udo
authors.initials: U
authors.lastname: Eilert
authors.forename: Wilson M
authors.initials: WM
authors.lastname: Njue
mesh_terms: D000818:Animals; D005638:Fruit / Q000737:chemistry; D008975:Molluscacides / Q000302:isolation & purification / Q000494:pharmacology*; D009844:Oligosaccharides / Q000302:isolation & purification / Q000494:pharmacology; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D012908:Snails / Q000187:drug effects*; D019657:Solanaceae / Q000737:chemistry*; D012991:Solanaceous Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D013256:Steroids / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D008975:Molluscacides; D009844:Oligosaccharides; D012991:Solanaceous Alkaloids; D013256:Steroids; C450167:solaculine A; C026609:beta-solamarine