EEG patterns in persons exposed to ionizing radiation as a result of the Chernobyl accident: part 1: conventional EEG analysis.
Prospective conventional EEG study was carried out 3-5 and 10-13 years after the Chernobyl accident (1986) in patients who had acute radiation sickness and in emergency workers in 1986 ("liquidators"). Control groups comprised healthy volunteers; veterans of the Afghanistan war with posttraumatic stress disorder; veterans with mild traumatic brain injury; and patients with dyscirculatory encephalopathy. In 3-5 years after irradiation, there were irritated EEG changes with paroxysmal activity shifted to the left frontotemporal region (cortical-limbic overactivation) that were transformed 10-13 years after irradiation toward a low-voltage EEG pattern with excess of fast (beta) and slow (delta) activity together with depression of alpha and theta activity (organic brain damage with inhibition of the cortical-limbic system). Quantitative EEG is likely to be very informative for investigation of dose-effect relationships.
Loganovsky
K N
KN
Department of Neurology, Research Centre for Radition Medicine of Academy of Medical Sciences of Ukraine, Kiev. kosti@morion.kiev.ua
Yuryev
K L
KL
D000328:Adult; D001921:Brain / Q000503:physiopathology / Q000528:radiation effects*; D015331:Cohort Studies; D004307:Dose-Response Relationship, Radiation; D004569:Electroencephalography / Q000528:radiation effects*; D005071:Evoked Potentials / Q000528:radiation effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis* / Q000503:physiopathology; D011210:Power Plants; D011832:Radiation Injuries / Q000175:diagnosis* / Q000503:physiopathology; D018788:Radioactive Hazard Release; D012016:Reference Values; D012066:Relief Work; D014455:Ukraine