title: Triterpenoid saponins from Mollugo spergula.
abstract: Two novel triterpenoid saponins belonging to a modified hopane group, spergulin A [3-O-(beta-D-xylopyranosyl 4-sulphate)-spergulagenin A] (1) and spergulin B [3-O-[alpha-rhamnopyranosyl (1-->2)-beta-D-xylopyranosyl]-spergulatriol] (4) were isolated from the aerial part of Mollugo spergula along with spergulacin (2) and spergulacin A (3). Their structures and relative stereochemistry were determined by a combination of 2D-NMR (COSY, TOCSY, HETCOR, NOESY and HMBC) and HR-FAB-MS analysis coupled with strategic chemical and enzymatic transformations.
authors.affiliation: Indian Institute of Chemical Biology, 4 Raja S C Mullick Road, Calcutta 700032, India. npsahu@iicb.res.in
authors.forename: N P
authors.initials: NP
authors.lastname: Sahu
authors.forename: K
authors.initials: K
authors.lastname: Koike
authors.forename: S
authors.initials: S
authors.lastname: Banerjee
authors.forename: B
authors.initials: B
authors.lastname: Achari
authors.forename: T
authors.initials: T
authors.lastname: Nikaido
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D012503:Saponins; D014315:Triterpenes