title: Crohn's disease presenting as a breast abscess: a case report.
abstract: A case of cutaneous Crohn's disease (CD) involving the areola-nipple region of both breasts in a 45-year-old woman is reported. The lesion had initially been diagnosed and treated as a simple abscess. Histopathological examination, however, showed granulomatous inflammation with eosinophils suggesting extraintestinal CD. The patient also had a minor area of cutaneous CD localized at the umbilicus and severe anogenital lesions. Twenty-six years previously the woman had undergone a course of sulphasalazine treatment together with steroid enema for chronic inflammatory colitis, but the colitis had been inactive for 25 years. Treatment with sulphasalazine, metronidazole, prednisolone and azothioprine had only minor effect on the skin lesions. CD is a systemic disorder and the most prominent manifestations may be extraintestinal.
authors.affiliation: Department of Medicine, Roskilde County Hospital in Køge (RASK), Denmark. karin.ladefoged@dadlnet.dk
authors.forename: K
authors.initials: K
authors.lastname: Ladefoged
authors.forename: E
authors.initials: E
authors.lastname: Balslev
authors.forename: G B
authors.initials: GB
authors.lastname: Jemec
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000473:pathology; D001941:Breast Diseases / Q000175:diagnosis* / Q000473:pathology; D003106:Colon / Q000473:pathology; D003424:Crohn Disease / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012867:Skin; D012871:Skin Diseases / Q000175:diagnosis* / Q000473:pathology