title: Fetal heart rate patterns in normal and ritodrine-treated pregnancies, detected by magnetocardiography.
abstract: OBJECTIVE
  The aim of the present study was to test the validity of magnetocardiography in the diagnosis of fetal heart rate arrhythmias in normal pregnancies, as compared to the number of arrhythmias reported in other series, which were detected by use of other diagnostic techniques. We also evaluated the influence of ritodrine on the fetal heart rhythm in pregnancies treated for the risk of preterm labor by means of magnetocardiography, in order to provide preliminary results that could be utilized in the future establishment of magnetocardiography as a screening procedure in the diagnosis and management of fetal arrhythmias.
  
  
  METHODS
  We performed a prospective study on two subgroups of pregnant women: one of 84 women with normal healthy singleton pregnancies and one of 68 pregnant women treated with ritodrine for the risk of preterm labor.
  
  
  RESULTS
  The prevalence of fetal arrhythmias in the first subgroup was 3.5% (3/84), while in the second subgroup the prevalence was 16% (11/68).
  
  
  CONCLUSIONS
  The incidence of fetal arrhythmias detected in our population of normal pregnancies was comparable to that reported in previous studies by use of other techniques. Results gained from the second subgroup, although not comparable to others, owing to lack of similar reports, led us to believe that magnetocardiography's advantages over conventional methods of fetal cardiac surveillance could highlight the technique as a useful screening procedure for the detection of preterm fetuses, which should be submitted to closer investigation, because of the arrhythmias caused by ritodrine infusion.
authors.affiliation: Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, Thrace, Greece.
authors.forename: P G
authors.initials: PG
authors.lastname: Anastasiadis
authors.forename: P
authors.initials: P
authors.lastname: Anninos
authors.forename: E
authors.initials: E
authors.lastname: Assimakopoulos
authors.forename: N
authors.initials: N
authors.lastname: Koutlaki
authors.forename: A
authors.initials: A
authors.lastname: Kotini
authors.forename: G
authors.initials: G
authors.lastname: Galazios
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000175:diagnosis*; D015148:Cardiotocography / Q000592:standards*; D005260:Female; D006340:Heart Rate, Fetal / Q000502:physiology; D006801:Humans; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D011237:Predictive Value of Tests; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced / Q000175:diagnosis*; D011446:Prospective Studies; D012312:Ritodrine / Q000009:adverse effects*; D015149:Tocolytic Agents / Q000009:adverse effects*; D016216:Ultrasonography, Prenatal / Q000592:standards*
chemical_list: D015149:Tocolytic Agents; D012312:Ritodrine