title: A STR mutation in a heteropaternal twin case.
abstract: A heteropaternal male twin case with two men being alleged fathers was investigated as requested by the Court. Up to 37 PCR-based polymorphic DNA systems were studied in this case which was complicated by a paternal ACTBP2 mutation detected in one twin. This is the first report on a STR mutation in a double paternity case where both biological fathers were indisputably identified. The STR systems enable the resolution of these complex genetic relationships even in a case where a mutation in one STR locus was encountered.
authors.affiliation: Department of Legal Medicine, Faculty of Medicine, University of Lisbon, Av. Prof. Egas Moniz, 1649-028 Lisbon, Portugal. hgeada@mail.telepac.pt
authors.forename: H
authors.initials: H
authors.lastname: Geada
authors.forename: T
authors.initials: T
authors.lastname: Ribeiro
authors.forename: R M
authors.initials: RM
authors.lastname: Brito
authors.forename: R
authors.initials: R
authors.lastname: Espinheira
authors.forename: B
authors.initials: B
authors.lastname: Rolf
authors.forename: C
authors.initials: C
authors.lastname: Hohoff
authors.forename: B
authors.initials: B
authors.lastname: Brinkmann
mesh_terms: D016172:DNA Fingerprinting; D005260:Female; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats; D009154:Mutation; D010334:Paternity; D020080:Tandem Repeat Sequences / Q000235:genetics*; D014429:Twins, Dizygotic / Q000235:genetics*