[Preoperative ultrasound evaluation of myometrial invasion in patients with endometrial carcinoma].
OBJECTIVE
To evaluate the diagnostic accuracy of preoperative transvaginal sonography in the detection of myometrial invasion in endometrial cancer patients classified by the grade of disease.


METHODS
Prospective multicenter study.


METHODS
Department of Obstetrics and Gynaecology, Medical Faculty, Palacky University, Olomouc, Czech Republic.


METHODS
In the period 1998-2001, 195 patients from 10 cooperating centers in the Czech Republic were enrolled in the RHOCE (risk of hysteroscopy in endometrial cancer) study. Sixteen patients did not meet the vaginal sonography study criteria (insufficient surgical staging, missing ultrasound examination). Sonographic results in 179 patients were categorized as M0--absence of infiltration (n = 97), M1--infiltration less than 1/2 myometrial depth (n = 61), M2--infiltration greater than 1/2 myometrial depth (n = 21). The final histopathology report of myoinvasion was used as a golden standard.


RESULTS
We proved lower accuracy of vaginal sonography in detecting myometrial invasion in patients with higher grade of disease.


CONCLUSIONS
Based on these data, the value of preoperative vaginal sonography as the sole criterion in the decision to perform extensive surgical procedures is questionable and warrants further evaluation.
Pilka
R
R
Gynekologicko-porodnická klinika LF UP Olomouc.
Kudela
M
M
Dzvincuk
P
P
D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000601:surgery; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D009215:Myometrium / Q000000981:diagnostic imaging* / Q000473:pathology; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography