title: Suicide in teenagers: assessment, management, and prevention.
abstract: Adolescents who kill themselves invariably have an underlying psychiatric disorder. Biological markers are not yet clinically useful for identifying adolescents at risk, and there is a paucity of research data on the effectiveness of behavioral intervention for suicidal teenagers. A case of a 16-year-old scholar and athlete is presented to illustrate how multiple risk factors and a family diathesis often go undetected, resulting in tragic consequences. Psychiatric, familial, genetic, and social risk factors of adolescent suicide are reviewed, and the efficacy of lithium and antidepressant pharmacotherapy in reducing suicide rates is discussed. The importance of screening adolescent patients for depression is emphasized. Although teenage suicide is rare and hard to predict, identifying and treating adolescents at risk is essential to further reduce teenage suicide.
authors.affiliation: National Institute of Mental Health, 3N238 Bldg 10, 9000 Rockville Pike, Bethesda, MD 20892, USA. zametkin@mail.nih.gov
authors.forename: A J
authors.initials: AJ
authors.lastname: Zametkin
authors.forename: M R
authors.initials: MR
authors.lastname: Alter
authors.forename: T
authors.initials: T
authors.lastname: Yemini
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000928:Antidepressive Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D003866:Depressive Disorder / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D005260:Female; D006760:Hospitalization; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D000297:Psychology, Adolescent; D011613:Psychotherapy; D012307:Risk Factors; D012701:Serotonin / Q000378:metabolism; D013405:Suicide / Q000523:psychology; D014365:Tryptophan Hydroxylase / Q000235:genetics; D000092864:Suicide Prevention
chemical_list: D000928:Antidepressive Agents; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D014365:Tryptophan Hydroxylase