Coregulation of ion channels by neurosteroids and phosphorylation.
This Perspective by Tasker is one of two discussing the regulation of ion channels by neurosteroids. Neurosteroids are steroids synthesized in the brain that act as allosteric modulators of ion-channel activity. The dual regulation of gamma-aminobutyric acid type A (GABA(A)) receptors and voltage-gated calcium channels by phosphorylation and neurosteroids is the focus of this Perspective.
Tasker
J
J
Department of Cell and Molecular Biology, Tulane University, New Orleans, LA, USA. tasker@tulane.edu
D015220:Calcium Channels / Q000502:physiology*; D006728:Hormones / Q000502:physiology*; D010766:Phosphorylation; D013256:Steroids / Q000502:physiology*
D015220:Calcium Channels; D006728:Hormones; D013256:Steroids