title: SWEET-DB: an attempt to create annotated data collections for carbohydrates.
abstract: Complex carbohydrates are known as mediators of complex cellular events. Concerning their structural diversity, their potential of information content is several orders of magnitude higher in a short sequence than any other biological macromolecule. SWEET-DB (http://www.dkfz.de/spec2/sweetdb/) is an attempt to use modern web techniques to annotate and/or cross-reference carbohydrate-related data collections which allow glycoscientists to find important data for compounds of interest in a compact and well-structured representation. Currently, reference data taken from three data sources can be retrieved for a given carbohydrate (sub)structure. The sources are CarbBank structures and literature references (linked to NCBI PubMed service), NMR data taken from SugaBase and 3D co-ordinates generated with SWEET-II. The main purpose of SWEET-DB is to enable an easy access to all data stored for one carbohydrate structure entering a complete sequence or parts thereof. Access to SWEET-DB contents is provided with the help of separate input spreadsheets for (sub)structures, bibliographic data, general structural data like molecular weight, NMR spectra and biological data. A detailed online tutorial is available at http://www.dkfz.de/spec2/sweetdb/nar/.
authors.affiliation: University Hildesheim, Institute of Physics and Technical Informatics, Marienburger Platz 22, 31141 Hildesheim, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Loss
authors.forename: Peter
authors.initials: P
authors.lastname: Bunsmann
authors.forename: Andreas
authors.initials: A
authors.lastname: Bohne
authors.forename: Annika
authors.initials: A
authors.lastname: Loss
authors.forename: Eberhard
authors.initials: E
authors.lastname: Schwarzer
authors.forename: Elke
authors.initials: E
authors.lastname: Lang
authors.forename: Claus-W
authors.initials: CW
authors.lastname: von der Lieth
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002241:Carbohydrates / Q000737:chemistry*; D003196:Computer Graphics; D016208:Databases, Factual; D005544:Forecasting; D006801:Humans; D021621:Imaging, Three-Dimensional; D016247:Information Storage and Retrieval; D020407:Internet; D019906:Nuclear Magnetic Resonance, Biomolecular; D011134:Polysaccharides / Q000737:chemistry
chemical_list: D002241:Carbohydrates; D011134:Polysaccharides