New excitement in cognitive space: between place cells and spatial memory.
Hippocampal principal neurons-'place cells'-exhibit location-specific firing. Recent work addresses the link between place cell activity and hippocampal memory function. New tasks that challenge spatial memory allow recording from single neurons, as well as ensembles of neurons, during memory computations, and insights into the cellular mechanisms of spatial memory are beginning to emerge.
Moser
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Neuroscience Unit and Department of Psychology, Norwegian University of Science and Technology, 7489 Trondheim, Norway. edvard.moser@svt.ntnu.no
Paulsen
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D000818:Animals; D003071:Cognition / Q000502:physiology*; D006624:Hippocampus / Q000166:cytology / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology; D013028:Space Perception / Q000502:physiology*