Nosological study of Borna disease virus infection in race horses.
To investigate the prevalence of diseases in the Borna disease virus (BDV) antibody positive race horses, we undertook seroepidemiological studies of BDV infection on 125 culled race horses in Hokkaido, Japan. The serological study disclosed the presence of antibodies only to BDV-p40 or -p24 in 19.2% (24/125) and 3.2% (4/125) of culled horses, respectively. Antibodies to both BDV-p40 and -p24 were found in 24.0% (30/125) of these horses. Of particular note was the finding that locomotorium disorders were detectable at a significantly higher rate in BDV antibody positive horses than that in the seronegative horses. These results imply that BDV infection may possibly contribute to an increase in the incidence rate of locomotorium disorders in race horses.
Hagiwara
Katsuro
K
Department of Veterinary Microbiology, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan. k-hagi@rakuno.ac.jp
Okamoto
Minoru
M
Kamitani
Wataru
W
Takamura
Shiki
S
Taniyama
Hiroyuki
H
Tsunoda
Nobuo
N
Tanaka
Hidetoshi
H
Iwai
Hiroshi
H
Ikuta
Kazuyoshi
K
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001890:Borna Disease / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D001891:Borna disease virus / Q000235:genetics / Q000276:immunology* / Q000302:isolation & purification; D001921:Brain / Q000821:virology; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D006734:Horse Diseases / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D006736:Horses; D017403:In Situ Hybridization / Q000662:veterinary; D007564:Japan / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D012367:RNA, Viral / Q000032:analysis; D016036:Seroepidemiologic Studies; D013177:Sports
D000914:Antibodies, Viral; D012367:RNA, Viral