Cyclopeptide alkaloids from stems of Paliurus ramossisimus.
Three 13-membered cyclopeptide alkaloids, paliurines G, H and I, together with six known alkaloids, nummularine H, daechuine-S3, paliurines A-C and F, were isolated from the stem of Paliurus ramossisimus by a combination of centrifugal partition chromatography and preparative TLC. Their structures were characterized and established on the basis of spectral analysis. A preliminary study indicated that nummularine H could shorten the methohexital induced sleeping time.
Lee
S S
SS
School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan, Republic of China. shoeilee@ha.mc.ntu.edu.tw
Su
W C
WC
Liu
K C
KC
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000302:isolation & purification; D018547:Plant Stems / Q000737:chemistry; D027823:Rhamnaceae / Q000737:chemistry*
D000470:Alkaloids; D010456:Peptides, Cyclic; C447015:paliurine G; C447014:paliurine H; C447013:paliurine I