title: Alkaloids from Cynanchum komarovii with inhibitory activity against the tobacco mosaic virus.
abstract: A pyrroloisoquinoline alkaloid, 2,3-dimethoxy-6-(3-oxo-butyl)-7,9,10,11,11a,12-hexahydrobenzo[f]pyrrolo[1,2-b]isoquinoline (1), whose structure was determined by spectroscopic methods, was isolated from the aerial parts of Cynanchum komarovii, together with two known alkaloids, 7-demethoxytylophorine (2) and 7-demethoxytylophorine N-oxide (3). Alkaloids 2 and 3 had antiviral activities against tobacco mosaic virus.
authors.affiliation: Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071People's Republic of China.
authors.forename: T
authors.initials: T
authors.lastname: An
authors.forename: R Q
authors.initials: RQ
authors.lastname: Huang
authors.forename: Z
authors.initials: Z
authors.lastname: Yang
authors.forename: D K
authors.initials: DK
authors.lastname: Zhang
authors.forename: G R
authors.initials: GR
authors.lastname: Li
authors.forename: Y C
authors.initials: YC
authors.lastname: Yao
authors.forename: J
authors.initials: J
authors.lastname: Gao
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D029062:Apocynaceae / Q000737:chemistry*; D014027:Tobacco Mosaic Virus / Q000187:drug effects*
chemical_list: D000470:Alkaloids; D000998:Antiviral Agents