title: Predictors of house-dust-mite allergen concentrations in dry regions in Australia.
abstract: BACKGROUND
  House-dust-mite allergen content differs between houses and is thought to be a function of the housing characteristics and furnishing choices that affect indoor microclimate and mite proliferation. The importance of these features may differ with regional climates.
  
  
  METHODS
  Concentrations of mite allergen were analysed as a function of housing features. Information on housing features was collected by questionnaire in 50 houses in two towns in a dry inland region of Australia. Mite allergen (Der p 1) was measured by ELISA in dust samples collected on five occasions over 2 years from beds and floors.
  
  
  RESULTS
  Der p 1 was detected in all houses. Many housing features did not influence mite allergen concentrations. However, the presence of evaporative cooling increased mite allergen by 3.34-fold in beds (P=0.007) and 3.94-fold in floors (P=0.003). Mite allergen was threefold higher in mattresses >5 years old, and synthetic and feather duvets tended to have higher and lower levels of mite allergen, respectively.
  
  
  CONCLUSIONS
  In houses in dry, inland regions of Australia, evaporative cooling and older mattresses are associated with higher concentrations of mite allergen. Alternative forms of air conditioning to evaporative cooling may be useful for control of mite allergen in dry regions.
authors.affiliation: The Institute of Respiratory Medicine, Royal Prince Alfred Hospital and University of Sydney, Missenden Road Post Office, NSW 2050, Sydney, Australia.
authors.forename: C H
authors.initials: CH
authors.lastname: Vanlaar
authors.forename: S H
authors.initials: SH
authors.lastname: Downs
authors.forename: T Z
authors.initials: TZ
authors.lastname: Mitakakis
authors.forename: J D
authors.initials: JD
authors.lastname: Leuppi
authors.forename: N G
authors.initials: NG
authors.lastname: Car
authors.forename: J K
authors.initials: JK
authors.lastname: Peat
authors.forename: G B
authors.initials: GB
authors.lastname: Marks
mesh_terms: D000485:Allergens / Q000032:analysis*; D000818:Animals; D039741:Antigens, Dermatophagoides; D001315:Australia; D003430:Cross-Sectional Studies; D004391:Dust / Q000032:analysis*; D004780:Environment, Controlled; D004797:Enzyme-Linked Immunosorbent Assay; D006023:Glycoproteins / Q000032:analysis*; D008925:Mites
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D004391:Dust; D006023:Glycoproteins