[Validation and approaches to correction of hemorheologic disorders in patients with gastrointestinal cancer].
A total of 237 patients were examined: 127 with gastric cancer and 110 with colonic cancer, 99 women and 138 men, mean age 57.5 years. Erythrocyte deformability and aggregation were studied by original methods. Red blood, protein metabolism, and endogenous intoxication parameters were evaluated by routine laboratory tests. Increased aggregation and volume of erythrocytes and decrease of their deformability and hemoglobin content in parallel with hypo- and dysproteinemia and increased level of endogenous intoxication were observed in all patients with gastrointestinal cancer. Correction of these disorders by intravenous laser exposure of the blood essentially improved the erythron status and protein metabolism and decreased endotoxicosis. Infusion/transfusion therapy also notably improved the erythron function and decreased endogenous intoxication. Analysis of the results of surgery showed decreased incidence of complications and lethal outcomes, which was due to methods of corrective therapy.
Karabanov
G N
GN
Karimov
A I
AI
Ogiĭ
I I
II
Gantsev
K Sh
KSh
Khalikov
R A
RA
Ishmuratova
R Sh
RSh
D001769:Blood / Q000528:radiation effects*; D001803:Blood Transfusion; D003627:Data Interpretation, Statistical; D004906:Erythrocyte Count; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000097:blood* / Q000601:surgery*; D006400:Hematocrit; D018056:Hemorheology; D006801:Humans; D007834:Lasers; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D011183:Postoperative Complications / Q000517:prevention & control