title: Impaired set-shifting ability and therapeutic response in obsessive-compulsive disorder.
abstract: Set-shifting ability and therapeutic response to serotonin reuptake inhibitors were investigated in 20 patients with obsessive-compulsive disorder. A clear relationship was found between impaired performance on two Wisconsin Card Sorting subtests (categories completed and perseverative errors) and positive treatment response.
authors.affiliation: Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil. lfontenelle@bigfoot.com
authors.forename: L
authors.initials: L
authors.lastname: Fontenelle
authors.forename: C
authors.initials: C
authors.lastname: Marques
authors.forename: E
authors.initials: E
authors.lastname: Engelhardt
authors.forename: M
authors.initials: M
authors.lastname: Versiani
mesh_terms: D000328:Adult; D001288:Attention / Q000187:drug effects*; D004193:Discrimination Learning / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D012718:Set, Psychology; D016896:Treatment Outcome
chemical_list: D017367:Selective Serotonin Reuptake Inhibitors