title: Sensitivity of spiral computed tomography scanning for detecting intraocular foreign bodies.
abstract: OBJECTIVE
  The purpose of this study is to determine whether 3-mm computed tomography (CT) cuts are equivalent to 1-mm CT cuts for detecting small intraocular foreign bodies (IOFBs).
  
  
  METHODS
  Experimental instrument validation study.
  
  
  METHODS
  Seventy-two porcine eyes were divided into three groups. Each group had 0.5 ml of human blood injected into the vitreous cavity and were surgically implanted with IOFBs.
  
  
  METHODS
  Each eye was surgically implanted with 0.5-mm metallic, 0.5-mm glass, or 0.5-mm stone IOFBs. Two additional eyes were left without IOFBs to serve as negative controls.
  
  
  METHODS
  Axial CT images of both 3-mm and 1-mm thickness were obtained and analyzed in masked fashion by two separate neuroradiologists.
  
  
  RESULTS
  The sensitivity for detecting 0.5-mm metallic, 0.5-mm glass, and 0.5-mm stone IOFBs with 3-mm CT images was 100%. The sensitivity for detecting 0.5-mm metallic, 0.5-mm glass, and 0.5-mm stone IOFBs with 1-mm CT images was also 100% (confidence interval, 95%; range, 0.88-1.00). Two negative control eyes without IOFBs were also correctly evaluated by the neuroradiologists.
  
  
  CONCLUSIONS
  With modern spiral CT scanning, 3-mm cuts are as sensitive as 1-mm cuts for detecting small metallic, glass, and stone IOFBs.
authors.affiliation: Associated Retinal Consultants, P.C. , R6007 Reichert Health Building, 5333 McAuley Drive, Ypsilanti, MI 48197, USA.
authors.forename: A B
authors.initials: AB
authors.lastname: Dass
authors.forename: P J
authors.initials: PJ
authors.lastname: Ferrone
authors.forename: Y R
authors.initials: YR
authors.lastname: Chu
authors.forename: M
authors.initials: M
authors.lastname: Esposito
authors.forename: L
authors.initials: L
authors.lastname: Gray
mesh_terms: D000818:Animals; D005129:Eye Foreign Bodies / Q000000981:diagnostic imaging*; D015807:Eye Injuries, Penetrating / Q000000981:diagnostic imaging*; D023421:Models, Animal; D012680:Sensitivity and Specificity; D013552:Swine; D014057:Tomography, X-Ray Computed; D014822:Vitreous Body / Q000000981:diagnostic imaging / Q000293:injuries*