Pharmacodynamic monitoring of lymphocyte proliferation and TGF-beta 1 expression at cyclosporine a (CyA) trough levels (C(0)) and 2 hours after intake (C(2)) of CyA in human renal allograft recipients.
Böhler
T
T
Department of Nephrology, Charité Campus Mitte, Humboldt-University, Berlin, Germany.
Budde
K
K
Schneider
M
M
Eliazyfer
S
S
Dell
K
K
Einecke
G
G
Diekmann
F
F
Fritsche
L
L
Mai
I
I
Neumayer
H H
HH
Waiser
J
J
D015703:Antigens, CD / Q000276:immunology; D017252:CD3 Complex / Q000276:immunology; D016572:Cyclosporine / Q000097:blood / Q000494:pharmacology / Q000627:therapeutic use*; D016903:Drug Monitoring / Q000379:methods; D006801:Humans; D007166:Immunosuppressive Agents / Q000097:blood / Q000494:pharmacology / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000276:immunology* / Q000502:physiology; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D008657:Metabolic Clearance Rate; D016212:Transforming Growth Factor beta / Q000096:biosynthesis / Q000097:blood; D014184:Transplantation, Homologous
D015703:Antigens, CD; D017252:CD3 Complex; D007166:Immunosuppressive Agents; D016212:Transforming Growth Factor beta; D016572:Cyclosporine