Synthesis of highly functionalised dibenzylglycine derivatives via the Suzuki-Miyaura coupling reaction.
Several alpha,alpha-dibenzylglycine (alpha-benzylphenylalanine) derivatives were prepared by alkylation of the ethyl isocyanoacetate with different benzyl bromide derivatives. Various aryl groups were introduced in the dibenzylglycine moiety via the Suzuki-Miyaura coupling reaction.
Kotha
Sambasivarao
S
Department of Chemistry, Indian Institute of Technology-Bombay, Mumbai 400 076, Powai, India. srk@chem.iitb.ac.in
Behera
Manoranjan
M
Kumar
Ramanatham Vinod
RV
D000478:Alkylation; D001593:Benzyl Compounds / Q000737:chemistry; D005998:Glycine / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D008722:Methods; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D001593:Benzyl Compounds; D010649:Phenylalanine; C097888:N,N-dibenzylglycine; D005998:Glycine; C038682:benzyl bromide