Liver transplantation for factor VII deficiency.
Factor VII deficiency is a serious, potentially lethal disorder of blood coagulation caused by a defect in hepatic factor VII synthesis. We report two children, sisters, both with severe, recurrent hemorrhagic complications from factor VII deficiency, successfully treated with orthotopic liver transplantation. Postoperatively, they remain symptom free with normal coagulation profiles.
Levi
D
D
Department of Surgery, University of Miami/Jackson Memorial Medical Center, FL, USA.
Pefkarou
A
A
Fort
J A
JA
DeFaria
W
W
Tzakis
A G
AG
D002648:Child; D002675:Child, Preschool; D005168:Factor VII Deficiency / Q000150:complications / Q000601:surgery*; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D016031:Liver Transplantation; D012008:Recurrence; D016896:Treatment Outcome