title: A freehand elastographic imaging approach for clinical breast imaging: system development and performance evaluation.
abstract: A prototype freehand elastographic imaging system has been developed for clinical breast imaging. The system consists of a fast data acquisition system, which is able to capture sequences of intermediate frequency echo frames at full frame rate from a commercial ultrasound scanner whilst the breast is deformed using hand-induced transducer motion. Two-dimensional echo tracking was used in combination with global distortion compensation and multi-compression averaging to minimise decorrelation noise incurred when stress is applied using hand-induced transducer motion. Experiments were conducted on gelatine phantoms to evaluate the quality of elastograms produced using the prototype system relative to those produced using mechanically induced transducer motion. The strain sensitivity and contrast-to-noise ratio of freehand elastograms compared favourably with elastograms produced using mechanically induced transducer motion. However, better dynamic range and signal-to-noise ratio was achieved when elastograms were created using mechanically induced transducer motion. Despite the loss in performance incurred when stress is applied using hand-induced transducer motion, it was concluded that the prototype system performed sufficiently well to warrant clinical evaluation.
authors.affiliation: Institute of Cancer Research, Sutton Surrey, UK. marvin.m.doyley@dartmouth.edu
authors.forename: M M
authors.initials: MM
authors.lastname: Doyley
authors.forename: J C
authors.initials: JC
authors.lastname: Bamber
authors.forename: F
authors.initials: F
authors.lastname: Fuechsel
authors.forename: N L
authors.initials: NL
authors.lastname: Bush
mesh_terms: D004548:Elasticity; D004867:Equipment Design; D005260:Female; D006801:Humans; D008962:Models, Theoretical; D019047:Phantoms, Imaging; D012815:Signal Processing, Computer-Assisted; D014159:Transducers; D016217:Ultrasonography, Mammary / Q000295:instrumentation* / Q000379:methods