title: Latent inhibition deficits in high-schizotypal normals: symptom-specific or anxiety-related?
abstract: Latent inhibition (LI) is the phenomenon in which subjects who have repeatedly experienced an irrelevant stimulus perform more poorly on a new learning task with that stimulus than with a novel stimulus, presumably because of a decline in stimulus-specific attention. The present article reviews the literature on LI deficits in high-schizotypal normal subjects and schizophrenic patients. Although LI-deficits have been thought to be specific to these groups, evidence is presented that the effects may be related to the anxiety components of high-schizotypality and related pathologies.
authors.affiliation: Department of Psychology, Tel Aviv University, Ramat Aviv 69978, Israel. braunh1@freud.tau.ac.il
authors.forename: H
authors.initials: H
authors.lastname: Braunstein-Bercovitz
authors.forename: T
authors.initials: T
authors.lastname: Rammsayer
authors.forename: H
authors.initials: H
authors.lastname: Gibbons
authors.forename: R E
authors.initials: RE
authors.lastname: Lubow
mesh_terms: D001007:Anxiety / Q000175:diagnosis* / Q000235:genetics / Q000523:psychology; D001288:Attention; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D007266:Inhibition, Psychological; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D012016:Reference Values; D012559:Schizophrenia / Q000175:diagnosis* / Q000235:genetics; D012565:Schizophrenic Psychology; D012569:Schizotypal Personality Disorder / Q000175:diagnosis* / Q000235:genetics / Q000523:psychology