AngioDB: database of angiogenesis and angiogenesis-related molecules.
Angiogenesis is the formation of new capillaries sprouting from pre-existing vessels. Angiogenesis occurs in a variety of normal physiological and pathological conditions and is regulated by a balance of stimulatory and inhibitory angiogenic factors. The control of this balance may fail and result in the formation of a pathologic capillary network during the development of many diseases. Therefore, we developed the angiogenesis database (AngioDB), which can provide a signaling network of angiogenesis-related biomolecules in human. Each record of AngioDB consisted of 12 fields and was developed by using a relational database management system. For the retrieval of data, Active Server Page (ASP) technology was integrated in this system. Users can access the database by a query or imagemap browsing program. The retrieving system also provides a list of angiogenesis-related molecules classified by three categories, and the database has an external link to NCBI databases. AngioDB is available via the Internet at http://angiodb.snu.ac.kr/.
Sohn
Tae-Kwon
TK
Graduate Program of Bioinformatics, Department of Molecular Biology, Pusan National University, Pusan 609-735, Korea.
Moon
Eun-Joung
EJ
Lee
Seok-Ki
SK
Cho
Hwan-Gue
HG
Kim
Kyu-Won
KW
D000595:Amino Acid Sequence; D043925:Angiogenesis Inducing Agents / Q000145:classification / Q000235:genetics*; D020533:Angiogenesis Inhibitors / Q000145:classification / Q000235:genetics*; D001483:Base Sequence; D003196:Computer Graphics; D030562:Databases, Protein; D005544:Forecasting; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D009389:Neovascularization, Pathologic; D018919:Neovascularization, Physiologic; D015398:Signal Transduction; D018511:Systems Integration
D043925:Angiogenesis Inducing Agents; D020533:Angiogenesis Inhibitors