title: Antecedents of adherence to antituberculosis therapy.
abstract: This correlational study identified antecedents of adherence to antituberculosis (anti-TB) therapy in a convenience sample of 62 English-speaking adults. From a demographic perspective, the study sample was similar to the referent population of TB patients in Georgia. A variety of parametric analyses revealed the following: The mean self-reported adherence score was 92.6% (SD = 3.3). Higher levels of self-reported adherence were associated with an annual income of $11,000 or more, education beyond high school, no current alcohol use, perceived support and absence of barriers to medication taking, strong intentions to adhere, and a high capacity for self-care. Those six variables accounted for 28% of adherence variance, F(6, 44) of 4.3, p = 0.0017. Additionally, belief in the usefulness and benefit of the medications was strongly correlated with intentions to adhere (r = 0.83, p < 0.001), and interpersonal aspects of care was significantly correlated with perceptions of medication utility (r = 0.65, p < 0.001), supports/barriers (r = 0.44, p < 0.001), intentions (r = 0.69, p < 0.001), and self-care (r = -0.42, p < 0.01). Persons who were diagnosed with both TB and human immunodeficiency virus (HIV) reported significantly lower adherence.
authors.affiliation: Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta 30322, USA. nurmmcd@nurse.emory.edu
authors.forename: M
authors.initials: M
authors.lastname: McDonnell
authors.forename: J
authors.initials: J
authors.lastname: Turner
authors.forename: M T
authors.initials: MT
authors.lastname: Weaver
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D003710:Demography; D005260:Female; D005845:Georgia; D006801:Humans; D008297:Male; D010349:Patient Compliance / Q000523:psychology / Q000706:statistics & numerical data*; D012648:Self Care; D012959:Socioeconomic Factors; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents