Cytomegalovirus enteritis after autologous peripheral blood stem cell transplantation.
A 61-year-old male with non-Hodgkin's lymphoma (peripheral T-cell lymphoma, unspecified, clinical stage IVb) received autologous peripheral blood stem cell transplantation (PBSCT) during first remission. He was seropositive for cytomegalovirus (CMV) prior to autologous PBSCT. His posttransplant clinical course was complicated by refractory CMV enteritis, which manifested persistent abdominal pain, diarrhea, and bloody stool. Generally, gastrointestinal CMV disease is relatively rare after autologous PBSCT. However, our case indicates that CMV infection must be considered as a differential diagnosis in cases of unexplained hemorrhagic enteritis following autologous PBSCT.
Kozuka
T
T
Second Department of Internal Medicine, Okayama University Medical School, Japan. kozuka@md.okayama-u.ac.jp
Takenaka
K
K
Shinagawa
K
K
Masuda
K
K
Ishihara
T
T
Arimori
Y
Y
Fukunaga
S
S
Maeda
Y
Y
Ishimaru
F
F
Kiura
K
K
Ikeda
K
K
Niiya
K
K
Harada
M
M
D015746:Abdominal Pain; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D003937:Diagnosis, Differential; D003967:Diarrhea; D004751:Enteritis / Q000821:virology*; D006471:Gastrointestinal Hemorrhage; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D014182:Transplantation, Autologous