title: The prediction of the structural class of protein: application of the measure of diversity.
abstract: Based on the concept that the structural class of a protein is mainly determined by its secondary structure sequence, a new algorithm for prediction of the structural class of a protein is proposed. By use of the number of alpha -helices, beta -strands, and betaalphabeta fragments, the structural class of a protein can be predicted by an algorithm based on the increment of diversity (ID), in which the sole prediction parameter-the increment of diversity is used as the index of prediction of structural class of a protein. The results indicate that the high rates of correct prediction are obtained for complete set (standard set) from Brookhaven Protein Data Bank-CD ROM (PDB) published in October 1995 and the test set newly released from Brookhaven Protein Data Bank-CD ROM (PDB) before July 1998, respectively.
authors.affiliation: Laboratory of Theoretical Biophysics, Inner Mongolia University, Hohhot, 010021, China. qzli@mail.imu.edu.cn
authors.forename: Q Z
authors.initials: QZ
authors.lastname: Li
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Lu
mesh_terms: D000465:Algorithms; D000818:Animals; D030562:Databases, Protein; D008956:Models, Chemical; D017433:Protein Structure, Secondary