Current issues in the biology of AIDS-related lymphoma.
Three important issues have been the focus of much recent attention in the biology of AIDS-related lymphomas. The altered epidemiology in the era of highly active antiretroviral therapy, the role of herpesviruses including human herpesvirus 8 and the molecular genetics of HIV-associated T-cell lymphomas. These topics are covered in this article and their potential application to the clinical management of AIDS-related lymphomas are discussed.
Bower
M
M
Department of Oncology, Chelsea and Westminster Hospital, London, UK. m.bower@ic.ac.uk
Fife
K
K
D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology*; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000235:genetics / Q000503:physiopathology* / Q000821:virology; D015999:Multivariate Analysis