title: Intrathecal baclofen therapy for spastic hypertonia.
abstract: Intrathecal baclofen is perhaps the most effective treatment for significant spasticity regardless of the origin. For appropriately selected patients, it can provide qualitative and quantitative improvements in quality of life. This article discusses the practical aspects and patient selection, trial, implant, and ongoing management of patients with intrathecal baclofen pump therapy.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Baylor College of Medicine/University of Texas, Houston, Texas, USA.
authors.forename: C B
authors.initials: CB
authors.lastname: Ivanhoe
authors.forename: A H
authors.initials: AH
authors.lastname: Tilton
authors.forename: G E
authors.initials: GE
authors.lastname: Francisco
mesh_terms: D001418:Baclofen / Q000008:administration & dosage / Q000627:therapeutic use*; D002547:Cerebral Palsy / Q000150:complications; D062787:Drug Overdose; D018755:GABA Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007278:Injections, Spinal; D009103:Multiple Sclerosis / Q000150:complications; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology; D018579:Patient Selection; D013119:Spinal Cord Injuries / Q000150:complications
chemical_list: D018755:GABA Agonists; D001418:Baclofen