Glyceroglycolipids from Serratula strangulata.
The rhizomes of Serratula strangulata yielded three glyceroglycolipids, i.e. 1,2-di-O-(9Z,12Z,15Z-octadecatrienoyl)-3-O-(6-amine-6-deoxy-alpha-D-glucosyl)-glycerol, 1,2-di-O-(9Z,12Z,15Z-octadecatrienoyl)-3-O-(6-p-hydroxy-phenyl-propionamido-6-deoxy-alpha-D-glucosyl)-glycerol and 1,2-di-O-(9Z,12Z,15Z-octadecatrienoyl)-3-O-[alpha-D-glucose(1-6)-beta-D-allose]-glycerol, as well as a known sesquiterpene lactone and three known phytoecdysones. Their structures were elucidated on the basis of spectral data, especially by 2D NMR spectroscopic methods and chemical conversion. These compounds exhibited significant antibacterial and antitumor activities.
Dai
J Q
JQ
National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, Gansu, People's Republic of China. daij1@21cn.edu.cn
Zhu
Q X
QX
Zhao
C Y
CY
Yang
L
L
Li
Y
Y
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D001412:Bacillus subtilis / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D004187:Disaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D005990:Glycerol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D014407:Tumor Cells, Cultured
C447024:1,2-di-O-(9,12,15-octadecatrienoyl)-3-O-(6-amine-6-deoxy-glucosyl)-glycerol; C447025:1,2-di-O-(9Z,12Z,15Z-octadecatrienoyl)-3-O-(glucose(1-6)-allose)-glycerol; D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D004187:Disaccharides; D005990:Glycerol