FBG and TC/HDL ratios in type 2 diabetes mellitus.
BACKGROUND
Presence of dyslipidemia, i.e. raised Total Cholesterol (TC) and decreased High Density Lipoproteins (HDL) is an established phenomenon in type 2 diabetes mellitus. Its relationship to the fasting blood sugar (FBG) level in both diabetics and non-diabetics has yet to be established. The present study aims to show such a relationship.


METHODS
150 subjects were selected and divided into two groups, one of 50 controls (non-diabetics), the other of 100 patients with type 2 diabetes mellitus. Their FBG levels were determined by enzyme oxidase method, and their TC and HDL levels were determined using a standard kit method.


RESULTS
FBG and TC:HDL ratios were increased in the patient group (p = < 0.001). Comparison of FBG and TC:HDL ratios revealed a highly significant rise (p = < 0.001) in the patient group. FBG with TC:HDL ratios between both groups showed a positive correlation (r = 0.554).


CONCLUSIONS
The results of the present study suggest an association between FBG and TC:HDL ratios, which may be a contributory factor to the increased prevalence of coronary artery disease in patients with type 2 diabetes mellitus.
Hanif
R
R
Department of Biochemistry, Ayub Medical College, Abbottabad.
Sattar
A
A
Qayum
I
I
D000328:Adult; D000368:Aged; D001786:Blood Glucose; D016022:Case-Control Studies; D008076:Cholesterol, HDL / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D005215:Fasting / Q000097:blood*; D006801:Humans
D001786:Blood Glucose; D008076:Cholesterol, HDL