title: Lanthony 15-Hue Desaturated Test for screening of early color vision defects in uncomplicated juvenile diabetes.
abstract: OBJECTIVE
  To identify the most appropriate test for screening of early color vision abnormalities in uncomplicated juvenile diabetes.
  
  
  METHODS
  Enrolled in this study were 39 diabetic adolescents, characterized by optimal Early Treatment Diabetic Retinopathy Study criteria for visual acuity, transparent dioptric means and angiographically normal retinas. Color vision was examined with Standard Pseudoisochromatic Plates (Part 2, SPP2), Roth 28-Hue Test (R28), Farnsworth-Munsell 100-Hue Tests (FM100), and Lanthony 15-Hue Desaturated Test (L15). Color confusion score (CCS) and desaturation angle (DSAT) were measured on L15 only. Thirty-nine normal subjects served as a control group. Poor metabolic control was an exclusion criteria.
  
  
  RESULTS
  CCS was significantly higher in the patients than in the controls (37.8 +/- 11.1 vs 0 +/- P < .001) and normal scores were found in only 4 diabetic patients. DSAT values were spread, not showing a well-defined axis of the defect. The results of FM100 were clinically reliable but affected by a longer execution time. R28 and SPP2 demonstrated a low sensitivity, as all patients scored normally with both tests.
  
  
  CONCLUSIONS
  Impaired color vision is a common observation even in patients with uncomplicated juvenile diabetes. Our results indicate that L15 is the most suitable test for screening of early color vision abnormalities in these subjects.
authors.affiliation: Institute of Ophthalmology, University La Sapienza, Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Giusti
mesh_terms: D000293:Adolescent; D003119:Color Perception Tests / Q000379:methods*; D003117:Color Vision Defects / Q000175:diagnosis* / Q000503:physiopathology; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D015351:Vision Screening / Q000379:methods*; D014792:Visual Acuity
chemical_list: D006442:Glycated Hemoglobin