title: Interferon therapy for orbital infiltration secondary to Erdheim-Chester disease.
abstract: OBJECTIVE
  To describe a 55-year-old male with Erdheim-Chester disease with bilateral orbital infiltration and visual loss who was successfully treated with interferon-alpha.
  
  
  METHODS
  Interventional case report.
  
  
  RESULTS
  The patient was treated with interferon-alpha and had an improvement in his clinical signs, including his visual acuity, after 4 weeks of interferon therapy.
  
  
  CONCLUSIONS
  Interferon-alpha can be effective in the treatment of orbital infiltration secondary to Erdheim-Chester disease.
authors.affiliation: Ophthalmology Section, Department of Plastic Surgery, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. besmaeli@mdanderson.org
authors.forename: B
authors.initials: B
authors.lastname: Esmaeli
authors.forename: A
authors.initials: A
authors.lastname: Ahmadi
authors.forename: R
authors.initials: R
authors.lastname: Tang
authors.forename: J
authors.initials: J
authors.lastname: Schiffman
authors.forename: R
authors.initials: R
authors.lastname: Kurzrock
mesh_terms: D005094:Exophthalmos / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D006099:Granuloma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D010026:Osteosclerosis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate; D014792:Visual Acuity; D014973:Xanthomatosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D016898:Interferon-alpha; D013669:Technetium Tc 99m Medronate