Visual fields and tiagabine: a quandary.
This case report describes the development of asymptomatic visual field defects (VFDs) in a psychiatric patient with bipolar disorder receiving adjunctive tiagabine treatment. These defects were apparently reversible upon the discontinuation of tiagabine. Controlled clinical trials are indicated to determine if this finding is indicative of a class effect for all GABAergic antiepileptic drugs (AEDs), as already noted with vigabatrin, or if this case represents an incidental finding with tiagabine (41 references).
Kaufman
K R
KR
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite #2200, New Brunswick, NJ 08901, USA. kaufmakr@umdnj.edu
Lepore
F E
FE
Keyser
B J
BJ
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009557:Nipecotic Acids / Q000009:adverse effects*; D012720:Severity of Illness Index; D000078308:Tiagabine; D014786:Vision Disorders / Q000139:chemically induced* / Q000175:diagnosis; D014794:Visual Fields / Q000187:drug effects*
D000927:Anticonvulsants; D009557:Nipecotic Acids; D000078308:Tiagabine