Anetoderma in a systemic lupus erythematosus patient with anti-PCNA and antiphospholipid antibodies.
Anetoderma is a rare elastolytic disorder included within the group of cutaneous atrophies. Its pathogenesis is not yet clearly established, but immunological mechanisms could play an important role in dermal elastolysis. It has been associated with different autoantibodies and autoimmune disorders. We present a case of anetoderma in a systemic lupus erythematosus patient with anti-proliferating-cell-nuclear-antigen and antiphospholipid antibodies, highlighting the peculiarities of such an association.
Alvarez-Cuesta
C C
CC
Department of Dermatology, Hospital Central de Asturias, University of Oviedo, Spain. cesarcos@ole.com
Raya-Aguado
C
C
Fernández-Rippe
M L
ML
Sánchez
T S
TS
Pérez-Oliva
N
N
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D017152:Antibodies, Antiphospholipid / Q000097:blood; D004547:Elastic Tissue / Q000473:pathology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology / Q000473:pathology; D008297:Male; D018809:Proliferating Cell Nuclear Antigen / Q000276:immunology; D012871:Skin Diseases / Q000150:complications* / Q000276:immunology / Q000473:pathology
D000974:Antibodies, Antinuclear; D017152:Antibodies, Antiphospholipid; D018809:Proliferating Cell Nuclear Antigen