Impaired set-shifting ability and therapeutic response in obsessive-compulsive disorder.
Set-shifting ability and therapeutic response to serotonin reuptake inhibitors were investigated in 20 patients with obsessive-compulsive disorder. A clear relationship was found between impaired performance on two Wisconsin Card Sorting subtests (categories completed and perseverative errors) and positive treatment response.
Fontenelle
L
L
Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil. lfontenelle@bigfoot.com
Marques
C
C
Engelhardt
E
E
Versiani
M
M
D000328:Adult; D001288:Attention / Q000187:drug effects*; D004193:Discrimination Learning / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D012718:Set, Psychology; D016896:Treatment Outcome
D017367:Selective Serotonin Reuptake Inhibitors