title: [A case of Mycobacterium intracellulare infection complicated by immotile cilia syndrome].
abstract: A 25-year-old woman with a history of immotile cilia syndrome (ICS) was admitted to our hospital with dyspnea. Chest roentgenography revealed dense infiltrates in both lower lung fields in addition to bronchiectasis and small nodular opacities, which had been observed previously. Transbronchial lung biopsy demonstrated evidence of non-caseating epithelioid cell granuloma. Sputum specimens were examined, and isolates were identified as Mycobacterium intracellulare. The patient was given antituberculous therapy and clarithromycin, which induced clinical improvement. It is well known that bronchial mucociliary transport is severely impaired in patients with ICS. However, to our knowledge, cases of M. intracellulare infection complicated by ICS have not been reported in Japan. We must pay close attention to the concurrence of these diseases.
authors.affiliation: Fifth Department of Internal Medicine, Hyogo College of Medicine, 1-1, Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: O
authors.initials: O
authors.lastname: Kitada
authors.forename: T
authors.initials: T
authors.lastname: Nakae
authors.forename: K
authors.initials: K
authors.lastname: Aragane
authors.forename: T
authors.initials: T
authors.lastname: Kodama
authors.forename: D
authors.initials: D
authors.lastname: Ihaku
authors.forename: T
authors.initials: T
authors.lastname: Nakagomi
authors.forename: N
authors.initials: N
authors.lastname: Takenaka
authors.forename: S
authors.initials: S
authors.lastname: Jin
authors.forename: M
authors.initials: M
authors.lastname: Nagasawa
authors.forename: M
authors.initials: M
authors.lastname: Sugita
mesh_terms: D000328:Adult; D002925:Ciliary Motility Disorders / Q000150:complications*; D005260:Female; D006801:Humans; D015270:Mycobacterium avium-intracellulare Infection / Q000209:etiology*