title: Bromonium ion-promoted glycosidic bond formation and simultaneous bromination of an activated aryl aglycon.
abstract: N-Bromosuccinimide (NBS) together with a catalytic amount of Me(3)SiOTf was found to be effective for the activation of thioglycosides. Concurrently with formation of the glycosidic bond, bromination took place on the activated aromatic ring of a 4-methoxyphenyl aglycon.
authors.affiliation: Department of Bioorganic Chemistry, School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083, PR China.
authors.forename: Zhi-Hui
authors.initials: ZH
authors.lastname: Qin
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Meng-Shen
authors.initials: MS
authors.lastname: Cai
authors.forename: Zhong-Jun
authors.initials: ZJ
authors.lastname: Li
mesh_terms: D001966:Bromine / Q000737:chemistry*; D001974:Bromosuccinimide / Q000737:chemistry*; D004187:Disaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013863:Thioglucosides / Q000737:chemistry*
chemical_list: D004187:Disaccharides; D013863:Thioglucosides; D001974:Bromosuccinimide; D001966:Bromine