Nanoscale powders and formulations with biocidal activity toward spores and vegetative cells of bacillus species, viruses, and toxins.
Certain formulations of nanoscale powders possess antimicrobial properties. These formulations are made of simple, nontoxic metal oxides such as magnesium oxide (MgO) and calcium oxide (CaO, lime) in nanocrystalline form, carrying active forms of halogens, for example, MgO. Cl2 and MgO. Br2. When these ultrafine powders contact vegetative cells of Escherichia coli, Bacillus cereus, or Bacillus globigii, over 90% are killed within a few minutes. Likewise, spore forms of the Bacillus species are decontaminated within several hours. Dry contact with aflatoxins and contact with MS2 bacteriophage (surrogate of human enterovirus) in water also causes decontamination in minutes.
Koper
Olga B
OB
Nanoscale Material, Inc. (formerly Nantek, Inc.), 1500 Hays Drive, Manhattan, KS 66502, USA.
Klabunde
John S
JS
Marchin
George L
GL
Klabunde
Kenneth J
KJ
Stoimenov
Peter
P
Bohra
Lalit
L
D000348:Aflatoxins / Q000494:pharmacology*; D000818:Animals; D001407:Bacillus / Q000187:drug effects*; D017610:Calcium Compounds / Q000494:pharmacology*; D015169:Colony Count, Microbial; D004202:Disinfectants / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects; D006219:Halogens / Q000494:pharmacology; D017909:Levivirus / Q000187:drug effects*; D008277:Magnesium Oxide / Q000494:pharmacology*; D036103:Nanotechnology; D010087:Oxides / Q000494:pharmacology*; D010316:Particle Size; D011208:Powders; D013170:Spores / Q000187:drug effects*; D014118:Toxins, Biological
D000348:Aflatoxins; D017610:Calcium Compounds; D004202:Disinfectants; D006219:Halogens; D010087:Oxides; D011208:Powders; D014118:Toxins, Biological; D008277:Magnesium Oxide; C016538:lime