title: Comparative analysis of Prx1 and Prx2 expression in mice provides evidence for incomplete compensation.
abstract: The family of paired-related homeobox genes to which Prx1 and Prx2 belong plays an integral role in limb and craniofacial development, as evidenced by both transgenic mice and in situ hybridization data. However, little is known about protein expression of these homeodomain transcription factors. Recent studies in our lab have established the pattern of Prx1 protein expression during normal mouse embryogenesis. Here we present a comparative analysis of Prx1 and Prx2 protein expression in the developing mouse using a novel anti-Prx2 antibody reagent.
authors.affiliation: Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
authors.forename: Elizabeth S
authors.initials: ES
authors.lastname: Chesterman
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Kern
mesh_terms: D000818:Animals; D015153:Blotting, Western; D005314:Embryonic and Fetal Development; D019084:Fluorescent Antibody Technique, Indirect; D018507:Gene Expression Regulation, Developmental; D006321:Heart / Q000196:embryology*; D006614:Hindlimb / Q000196:embryology / Q000378:metabolism; D007150:Immunohistochemistry; D066298:In Vitro Techniques; D051379:Mice; D009206:Myocardium / Q000378:metabolism*; D010544:Peroxidases / Q000276:immunology / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins; D012886:Skull / Q000196:embryology* / Q000378:metabolism
chemical_list: D029701:Saccharomyces cerevisiae Proteins; C410041:PRX1 protein, S cerevisiae; D010544:Peroxidases; C120494:anionic peroxidase