title: Ferredoxins of the third kind.
abstract: Most low-potential ferredoxins (Fds) are of the well-known [2Fe-2S] plant or [4Fe-4S] bacterial type. Yet, an additional class of [2Fe-2S] Fds has been recognized on the basis of sequence and spectroscopic idiosyncrasies. A recent crystal structure has confirmed the uniqueness of this third kind of Fd, and shown that these proteins display an unexpected structural similarity to thioredoxin. The properties of these thioredoxin-like [2Fe-2S] Fds are summarized, and hypotheses concerning their function are discussed.
authors.affiliation: Laboratoire de Bioénergétique Cellulaire et Pathologique, Département de Biologie Moléculaire et Structurale, CEA-Grenoble, 38054, Grenoble, France. jaques.meyer@cea.fr
authors.forename: J
authors.initials: J
authors.lastname: Meyer
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry; D018360:Crystallography, X-Ray; D005288:Ferredoxins / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011487:Protein Conformation; D017510:Protein Folding; D017434:Protein Structure, Tertiary; D017386:Sequence Homology, Amino Acid; D013053:Spectrophotometry
chemical_list: D001426:Bacterial Proteins; D005288:Ferredoxins