Central nervous system infection during immunosuppression.
Suppression of the immune system by human immunodeficiency virus (HIV) infection or immunosuppressive therapy following transplantation increases susceptibility to CNS infection. Examination of the level and type of immunosuppression, in addition to the clinical and radiologic findings at the time of diagnosis can aid the clinician in determining the most likely etiology of infection. This article discusses how suppression of the host immune status modifies the presentation and diagnosis of selected CNS infections and the recommended treatment for these infections.
Zunt
Joseph R
JR
Department of Neurology, University of Washington School of Medicine, Seattle, Washington 98104, USA. jzunt@u.washington.edu
D001706:Biopsy; D001921:Brain / Q000473:pathology; D002494:Central Nervous System Infections / Q000175:diagnosis / Q000276:immunology* / Q000382:microbiology; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*