A novel alkaloid serantrypinone and the spiro azaphilone daldinin D from Penicillium thymicola.
The novel quinazoline metabolite serantrypinone (1) has been isolated from an isolate of the microfungus Penicillium thymicola together with daldinin D (2), a new peracetylated spiro azaphilone derivative. The structures of 1 and 2 were elucidated by analysis of spectroscopic data, including 2D NMR, and comparison with literature data.
Romero Ariza
M
M
Department of Organic Chemistry, University of Granada, Avdn. Fuentenueva, Spain.
Larsen
T O
TO
Petersen
B O
BO
Duus
J Ø
JØ
Christophersen
C
C
Barrero
A F
AF
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D007211:Indoles; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010407:Penicillium / Q000737:chemistry*; D011714:Pyrans; D011799:Quinazolines / Q000737:chemistry / Q000302:isolation & purification*; D013056:Spectrophotometry, Ultraviolet; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification*
D000470:Alkaloids; D007211:Indoles; D011714:Pyrans; D011799:Quinazolines; D013141:Spiro Compounds; C446565:daldinin D; C446564:serantrypinone