title: Congenital absence of the internal carotid artery: case reports and review of the collateral circulation.
abstract: Absence of the internal carotid artery (ICA) is a rare congenital anomaly. The embryology of the ICA and the common collateral pathways associated with its congenital absence are reviewed, with four new cases provided for illustration. While collateral blood flow may allow these patients to remain asymptomatic, two of our patients presented with transient ischemic attacks. Recognition of this anomaly has important implications during planned carotid or transsphenoidal surgery, in thromboembolic disease, and in the surveillance and detection of associated cerebral aneurysms.
authors.affiliation: Department of Neuroradiology, Wake Forest University Baptist Medical Center, Winston-Salem, NC 27157, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Given
authors.forename: F
authors.initials: F
authors.lastname: Huang-Hellinger
authors.forename: M D
authors.initials: MD
authors.lastname: Baker
authors.forename: N B
authors.initials: NB
authors.lastname: Chepuri
authors.forename: P P
authors.initials: PP
authors.lastname: Morris
mesh_terms: D000328:Adult; D002343:Carotid Artery, Internal / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000196:embryology; D002560:Cerebrovascular Circulation; D003097:Collateral Circulation; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D011859:Radiography