Proton transport mechanism of bacteriorhodopsin as revealed by site-specific mutagenesis and protein sequence variability.
A large share of the current ideas about the mechanism of proton transport by bacteriorhodopsin has emerged from studies of site-specific mutants. This review is an attempt to check some of these ideas against the natural variability in the primary structure of the protein.
Brown
L S
LS
Department of Physiology and Biophysics, University of California, Irvine, California, 92697, USA. lsbrown@uci.edu
D000595:Amino Acid Sequence; D001436:Bacteriorhodopsins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D011522:Protons; D017386:Sequence Homology, Amino Acid
D011522:Protons; D001436:Bacteriorhodopsins