Suppression of reflex saliva from rat parotid gland following intracerebroventricular injection of hypertonic NaCl and sucrose.
These effects were studied in conscious rats. Salivary volume and flow rate induced by eating solid diet were decreased by both the hypertonic solutions, compared with the effects of normal saline. This finding suggests that central osmotic perception affects parotid salivary secretion in rats.
Ito
Kayoko
K
Department of Physiology, Kyushu Dental College, 2-6-1 Manazuru, Kokurakita-ku, 803-8580, Kitakyushu, Japan.
Morikawa
Masao
M
Inenaga
Kiyotoshi
K
D000818:Animals; D006982:Hypertonic Solutions; D007276:Injections, Intraventricular; D008297:Male; D008845:Microinjections; D009997:Osmotic Pressure; D010306:Parotid Gland / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D012018:Reflex / Q000187:drug effects*; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage / Q000494:pharmacology*; D012472:Salivation / Q000187:drug effects*; D012636:Secretory Rate / Q000187:drug effects; D012965:Sodium Chloride / Q000008:administration & dosage / Q000494:pharmacology; D013223:Statistics as Topic; D013395:Sucrose / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D014882:Water-Electrolyte Balance
D006982:Hypertonic Solutions; D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride; D013395:Sucrose