[Diagnostic accuracy of frequency doubling perimetry].
OBJECTIVE
To evaluate the capacity of Frequency Doubling Perimetry (FDP) to classify normal subjects and patients with glaucoma.


METHODS



METHODS
cross sectional. 54 glaucoma patients (mean age 65 S.D. 9.3 years) and 54 normal subjects matched in age (64.2 S.D. 9.8 years) were examined. Normal subjects showed an intra-ocular pressure (IOP) of </= 21 mmHg, a normal optic disc appearance (disc stereophotos) and normal standard perimetry (Humphrey II, 24-2 full threshold or SITA standard programs). Glaucoma subjects presented an IOP>21 mmHg, a glaucomatous optic nerve and a glaucomatous standard perimetry. One eye per patient was selected at random. All were examined using FDP C-20-5 and N-30 programs. Sensitivity, specificity and receiver operating feature curves (ROC) for N-30 parameters were calculated. A quantitative correlation with standard perimetry (Pearson) was calculated as well.


RESULTS
Sensitivity and specificity for C-20-5 resulted in 74% and 96% respectively and 88% and 92% respectively for N-30. ROC area for mean deviation was 0.85 and 0.93 for the standard pattern deviation. Standard deviation in the FDP pattern showed a strong linear correlation with the Humphrey 24-2 standard deviation pattern (r(2)= 0.76, P<0.001).


CONCLUSIONS
The FDP N-30 could classify normal and glaucoma subjects with a high sensitivity and specificity. There was strong correlation between FDP and standard perimetry parameters.
Andrada
M T
MT
Hospital General de Segovia e Instituto Universitario de Oftalmobiología Aplicada, Universidad de Valladolid, Valladolid, España.
Bernaldo De Quirós
P
P
Villegas
R S
RS
Antón
A
A
D000368:Aged; D003430:Cross-Sectional Studies; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D058609:Visual Field Tests / Q000379:methods*