Efficient strategy for the synthesis of stereopentad subunits of scytophycin, rifamycin S, and discodermolide.
[reaction: see text] An efficient, simple method has been developed for the stereocontrolled synthesis of polypropionate stereopentads in high enantio- and diastereomeric purities.
BouzBouz
S
S
Laboratoire de Chimie Organique associé au CNRS, ESPCI, 10 rue Vauquelin, 75231 - Paris Cedex 05, France.
Cossy
J
J
D000447:Aldehydes / Q000737:chemistry; D000473:Alkanes; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry; D002219:Carbamates; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis / Q000737:chemistry*; D011753:Pyrones; D012294:Rifamycins / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D000473:Alkanes; D000970:Antineoplastic Agents; D002219:Carbamates; D007783:Lactones; D011714:Pyrans; D011753:Pyrones; D012294:Rifamycins; C080065:scytophycin A; C071229:discodermolide; C032779:rifamycin S