Isolation of drug-resistant tubercle bacilli in cutaneous tuberculosis.
Cutaneous tuberculosis in a teenage boy that did not respond to conventional antitubercular therapy is described. Mycobacterium tuberculosis was recovered on culture and found to be resistant to rifampicin and isoniazid. Gradual regression of the lesions was observed after the addition of streptomycin and ethambutol. Later streptomycin was stopped and the boy was advised to continue ethambutol along with ofloxacin and thioacetazone until complete regression was achieved.
Ramesh
V
V
Department of Dermatology and Microbiology, Safdarjang Hospital, New Delhi, India.
Murlidhar
S
S
Kumar
J
J
Srivastava
L
L
D000293:Adolescent; D000904:Antibiotics, Antitubercular / Q000627:therapeutic use*; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004977:Ethambutol / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification*; D013307:Streptomycin / Q000627:therapeutic use; D014382:Tuberculosis, Cutaneous / Q000188:drug therapy*; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy*
D000904:Antibiotics, Antitubercular; D000995:Antitubercular Agents; D004977:Ethambutol; D013307:Streptomycin