[Does resection of pituitary adenoma and radiotherapy cure the patient's symptoms?].
Today, pituitary adenomas are readily amenable to surgical treatment, and complication rates are low. With the exception of prolactin-producing adenomas, transsphenoidal or transcranial surgery is usually the treatment of choice. Indications for surgery are considered to be visual field deficits, functional disorders of the optomotor cranial nerves, or hypo-/hyperfunction of the pituitary. If treatment leads to normalization of the secretory dynamics, the long-term prognosis is favorable. If residual tumor or persistent overproduction of pituitary hormones is detected postoperatively, radiotherapy is applied. Endoscopic surgical procedures, intra-operative imaging and peri-operative determination of hormone levels enable the radicality of tumor removal to be further increased.
Buchfelder
M
M
Ltd. Oberarzt der Neurochirurgischen Klinik mit Poliklinik, Universität Erlangen-Nürnberg. buchfelder@nch.imed.uni-erlangen.de
D000172:Acromegaly / Q000601:surgery; D000236:Adenoma / Q000532:radiotherapy* / Q000601:surgery*; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000097:blood / Q000378:metabolism; D003131:Combined Modality Therapy; D003480:Cushing Syndrome / Q000601:surgery; D006801:Humans; D009347:Nelson Syndrome / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D010911:Pituitary Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D015175:Prolactinoma / Q000532:radiotherapy* / Q000601:surgery*; D011879:Radiotherapy Dosage
D000324:Adrenocorticotropic Hormone