Effect of sodium nitroprusside on hemodynamics of corpus cavernosum in Chinese.
OBJECTIVE
To study the effect of sodium nitroprusside (SNP) on the hemodynamics of corpus cavernosum in Chinese men with erectile dysfunction (ED).


METHODS
In 68 ED patients receiving intracavernous injection (ICI) of SNP, the cavernous hemodynamics were studied by Doppler ultrasonography.


RESULTS
The peak flow velocity (PFV), the artery diameter (Ad), the mean velocity of arterial blood (MV) and the vein diameter (Vd) were significantly higher after ICI of SNP than before ICI, but the end diastolic velocity (EDV) did not change significantly.


CONCLUSIONS
The increase in Vd after SNP suggests that the venous outflow is not invariably decreased during penile erection.
Fu
Q
Q
Department of Urology, Shanghai Ninth People's Hospital, Shanghai Second Medical University, China. jamesqfu@yahoo.com.cn
Yao
D H
DH
Jiang
Y Q
YQ
D000328:Adult; D000368:Aged; D002681:China; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020030:Nitric Oxide Donors / Q000008:administration & dosage / Q000494:pharmacology*; D009599:Nitroprusside / Q000008:administration & dosage / Q000494:pharmacology*; D010410:Penile Erection / Q000187:drug effects; D013737:Testis / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000187:drug effects*; D018608:Ultrasonography, Doppler
D020030:Nitric Oxide Donors; D009599:Nitroprusside