Cerebral protection before, during and after neurosurgical procedures.
Not only the pathology but also the neurosurgical procedure itself can lead to an impairment of cerebral structures. This may cause neurological symptoms like confusion, disorientation or cognitive deficits which have hardly been noticed until now. Neuroprotective substances can help to reduce this. As an example of the effectiveness, based on our own experiences and international trials, two different medical drugs, Nimodipine and Cerebrolysin, are presented. In conclusion one has to realize that nowadays neurosurgeons have to focus their interest more and more to neuroprotective adjuvant treatment possibilities.
Matula
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Neurosurgical Department, University of Vienna, Austria. Christian-Matula@univie.ac.at
Schoeggl
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D000596:Amino Acids / Q000627:therapeutic use*; D001925:Brain Damage, Chronic / Q000209:etiology / Q000517:prevention & control*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003072:Cognition Disorders / Q000209:etiology / Q000517:prevention & control*; D003244:Consciousness Disorders / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D019635:Neurosurgical Procedures / Q000009:adverse effects; D009553:Nimodipine / Q000627:therapeutic use*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control*; D011229:Preanesthetic Medication; D016634:Radiosurgery / Q000009:adverse effects; D013345:Subarachnoid Hemorrhage / Q000150:complications; D020301:Vasospasm, Intracranial / Q000209:etiology / Q000517:prevention & control*
D000596:Amino Acids; D002121:Calcium Channel Blockers; D018696:Neuroprotective Agents; C006952:cerebrolysin; D009553:Nimodipine