title: Synchronous vulvar and breast cancer.
abstract: Synchronous vulvar and breast cancer is rare. A 44-year-old women presented with a lesion in the right labia majora and right upper quadrant breast lump. After work-up, she underwent radical wide local vulvar excision and modified radical mastectomy with axillary lymph node dissection. The pathology of the vulva revealed moderately-differentiated squamous cell carcinoma and that of the breast infiltrating ductal carcinoma. Only two such cases have been previously reported: one was an elderly patient and the second a young patient with HIV infection. Our patient is a young and healthy woman making her presentation a unique and rare case.
authors.affiliation: Department of Obstetrics and Gynecology, American University of Beirut Medical Center, P.O. Box 113-6044-6A, Beirut, Lebanon. aa06@aub.edu.lb
authors.forename: A
authors.initials: A
authors.lastname: Abu-Musa
authors.forename: A
authors.initials: A
authors.lastname: Khalil
authors.forename: G
authors.initials: G
authors.lastname: Ghaziri
authors.forename: M
authors.initials: M
authors.lastname: Seoud
authors.forename: J
authors.initials: J
authors.lastname: Abbas
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001365:Axilla; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D009378:Neoplasms, Multiple Primary; D011878:Radiotherapy; D011980:Receptors, Progesterone / Q000032:analysis; D013629:Tamoxifen / Q000627:therapeutic use; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000601:surgery / Q000628:therapy
chemical_list: D004965:Estrogen Antagonists; D011980:Receptors, Progesterone; D013629:Tamoxifen