Thrombolytic therapy in acute ischemic stroke patients with cardiac thrombus.
The authors describe the outcome of five patients with a cardiac thrombus selected among 183 patients with stroke (2.7 %) who were given IV tissue plasminogen activator (tPA). No early systemic or cerebral embolism occurred. Two patients made a complete recovery at 3 months. Two patients had a moderate outcome. One patient had late recurrent cerebral embolism and died. These data suggest that the presence of a cardiac thrombus is not associated with a high risk of recurrent embolism in patients with stroke who are given IV tPA.
Derex
L
L
Service d'Urgences Neurovasculaires, Hôpital Neurologique, Lyon, France. lderex@yahoo.com
Nighoghossian
N
N
Perinetti
M
M
Honnorat
J
J
Trouillas
P
P
D000368:Aged; D000369:Aged, 80 and over; D000075202:Contraindications; D005260:Female; D006325:Heart Atria; D006352:Heart Ventricles; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000188:drug therapy*; D007262:Infusions, Intravenous; D020766:Intracranial Embolism / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
D010959:Tissue Plasminogen Activator