Distribution of angiotensin converting enzyme gene polymorphism among Northern Hans, Dahurs, and Ewenks.
OBJECTIVE
To observe the polymorphism of angiotensin-converting enzyme (ACE) gene in Northern Hans, Dahurs, and Ewenkis of China.


METHODS
The polymerase chain reaction was used to type the insertion/deletion polymorphism at intron 16 of ACE gene among 90 Northern Hans, 84 Dahurs, and 64 Ewenkis individuals. The experiment displayed the distribution in three kinds of ACE genotype: ID (heterozygotes of insertion and deletion), DD (homozygotes of deletion), and II (homozytes of insertion).


RESULTS
In Northern Hans the percentages of the distributing ACE I/D genotype were ID 27.8 %, DD 17.8 %, and II 54.4 %. The I/D genotype frequency of Dahurs individuals were ID 60.7 %, DD 26.2 %, and II 13.1 %. The Ewenkis genotype frequency were ID 70.3 %, DD 21.9 %, and II 7.8 %.


CONCLUSIONS
The polymorphism of ACE gene of Northern Hans is different from that of Dahurs and Ewenkis in China.
Zhang
Y M
YM
The Research Institute of Cardiovascular Diseases, Zhongshan Hospital of Fudan University, Shanghai 200032, China.
Zhang
L Y
LY
Wang
K Q
KQ
Ge
J B
JB
D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D005006:Ethnicity; D005838:Genotype; D006801:Humans; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D011110:Polymorphism, Genetic
D007703:Peptidyl-Dipeptidase A