[Nasal allergenic provocation test].
This is a method to evaluate both specific sensitivity to allergens in the nasal mucosa, IgE-mediated hypersensitivity, and antiinflammatory and antiallergic drugs efficacy, whose objectives are for research in diagnosis and treatment. The method is based in allergen extracts delivery in the nasal mucosa and the post-challenge measurement of rhinitis symptoms, vasoactive mediators release quantification and nasal obstruction degree evaluated by rhinomanometry. Nasal allergen challenge is a procedure of diagnostic and therapeutic evaluation usefulness, that must be performed in selected patients, in adequate facilities, by experts physicians, with standardised allergen dosages, in an specific nasal area, with objective measurements (rhinomanometry, mediators and secretions of the allergic response) and symptoms scoring that allow get reliable results in patients with allergic rhinitis under study.
Becerril Angeles
M H
MH
Servicio de alergia e inmunología clínica, Hospital de Especialidades, Centro Médico Nacional La Raza, IMSS.
Pérez López
A
A
Azuara Pliego
E
E
D000485:Allergens; D006801:Humans; D009299:Nasal Provocation Tests; D012680:Sensitivity and Specificity
D000485:Allergens