Tremor associated with benign IgM paraproteinaemic neuropathy successfully treated with gabapentin.
We describe a 76-year-old patient with a severe tremor due to chronic demyelinating neuropathy associated with a benign IgM paraproteinaemia that was successfully treated with gabapentin. The patient reached the full dose of 1,200 mg/day of gabapentin without side effects and showed a significant therapy-related improvement of tremor and disability, as judged by the Fahn Tolosa Marin Rating Scale.
Saverino
A
A
Department of Neurological Sciences and Vision, University of Genoa, Genoa, Italy.
Solaro
C
C
Capello
E
E
Trompetto
C
C
Abbruzzese
G
G
Schenone
A
A
D000085:Acetates / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D000588:Amines; D000978:Antiparkinson Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003509:Cyclohexanecarboxylic Acids; D005260:Female; D000077206:Gabapentin; D006225:Hand; D006801:Humans; D007075:Immunoglobulin M; D010265:Paraproteinemias / Q000150:complications* / Q000188:drug therapy*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014202:Tremor / Q000209:etiology*; D005680:gamma-Aminobutyric Acid
D000085:Acetates; D000588:Amines; D000978:Antiparkinson Agents; D003509:Cyclohexanecarboxylic Acids; D007075:Immunoglobulin M; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin