Recurrence of Wegener's granulomatosis 13 years after renal transplantation.
Wegener's granulomatosis (WG) can cause renal failure, requiring long-term renal replacement therapy. Renal transplantation in patients with WG is successful, but the risk for recurrence of the disease necessitates continued vigilance. We report a patient that originally presented with acute renal failure secondary to a pauci-immune focal necrotizing crescentic glomerulonephritis. Subsequent nasal involvement and serologic tests for antineutrophil cytoplasmic antibodies suggested a diagnosis of WG.
Fan
S L
SL
Department of Nephrology, Bart's and The London Hospital, Whitechapel, London, UK.
Lewis
K E
KE
Ball
E
E
Dodd
S
S
Raftery
M J
MJ
Yaqoob
M M
MM
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D014890:Granulomatosis with Polyangiitis / Q000628:therapy*; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D055502:Secondary Prevention
D019268:Antibodies, Antineutrophil Cytoplasmic; D015415:Biomarkers; D011239:Prednisolone