title: Hepatobiliary manifestations of cystic fibrosis in children: correlation of CT and US findings.
abstract: METHODS
  Abdominal US and CT scans of 50 pediatric cystic fibrosis (CF) patients were evaluated to search for specific data that can be attributed to the involvement of the hepatobiliary system. The liver findings of the two patients who were HBs antigen carriers were excluded from the study.
  
  
  RESULTS
  30 out of 48 patients had at least one abnormal finding of liver on CT and/or US. Although increased echogenicity of the liver was detected in 24 of 48 patients (50%), only six of these (12%) were regarded as steatosis according to CT criteria of low attenuation values. CT and US scans both showed unique multilobular fatty pattern, described as "pseudomasses" in three patients. Increased periportal echogenicity was seen in 18 (37%) patients on US, while CT could not demonstrate any sign of increased periportal thickness. Findings of cirrhosis were present in five patients with either modalities. Lymph nodes of less than 10-15 mm in diameter were detected at the hepatico-duodenal ligament in 18 (37%) patients. Anomalies of the gallbladder (absence or microgallbladder or stone) were detected in 12 cases (24%).
  
  
  CONCLUSIONS
  Although US is the most widely used modality in CF patients, CT and US correlation will help to better delineate the abnormalities between steatosis and periportal fibrosis and increase the sensitivity of the imaging methods to achieve the most accurate diagnosis.
authors.affiliation: Department of Radiology, Hacettepe University School of Medicine, Sihhiye, Ankara TR-06100, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Akata
authors.forename: Okan
authors.initials: O
authors.lastname: Akhan
authors.forename: Ugur
authors.initials: U
authors.lastname: Ozcelik
authors.forename: Mustafa N
authors.initials: MN
authors.lastname: Ozmen
authors.forename: Levent
authors.initials: L
authors.lastname: Oguzkurt
authors.forename: Mithat
authors.initials: M
authors.lastname: Haliloglu
authors.forename: Ayhan
authors.initials: A
authors.lastname: Göcmen
mesh_terms: D000293:Adolescent; D001659:Biliary Tract / Q000000981:diagnostic imaging* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D011859:Radiography; D014463:Ultrasonography