Picometer-scale dynamical x-ray imaging of single DNA molecules.
Time-resolved dynamical x-ray imaging of individual DNA molecules with picometer-scale precision is demonstrated for the first time. Diffracted x-ray tracking (DXT), a single-molecule experiment with x rays, monitors the rotating motions, rather than the translational motions, of a labeled nanocrystal. DXT can obtain information about the dynamics of single molecules through a quantitative analysis, since the signals from DXT are independent of the chemical conditions.
Sasaki
Y C
YC
Biomedical Group, Japan Synchrotron Radiation Research Institute, SPring-8, Mikazuki, Hyogo 679-5198, Japan. ycsasaki@spring8.or.jp
Okumura
Y
Y
Adachi
S
S
Suda
H
H
Taniguchi
Y
Y
Yagi
N
N
D004247:DNA / Q000737:chemistry*; D014961:X-Ray Diffraction
D004247:DNA