Paraneoplastic syndromes associated with lung cancer: a unique case of concomitant subacute cerebellar degeneration and Lambert-Eaton myasthenic syndrome.
We report an unusual case in which a patient with paraneoplastic subacute cerebellar degeneration (a brain disorder resulting from antibody production by a tumor located outside the skull) developed Lambert-Eaton Myasthenic Syndrome (antibody-mediated skeletal muscle weakness) that was not apparent until she underwent surgery. Failure to recognize this disease process can cause life-threatening respiratory distress.
Leonovicz
B M
BM
Department of Anesthesiology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Gordon
E A
EA
Wass
C T
CT
D000368:Aged; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis*; D005260:Female; D006801:Humans; D015624:Lambert-Eaton Myasthenic Syndrome / Q000150:complications / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis*; D020362:Paraneoplastic Cerebellar Degeneration / Q000150:complications / Q000175:diagnosis*; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*