Determinants of spike timing-dependent synaptic plasticity.
Recent studies show that the precise timing of presynaptic inputs and postsynaptic action potentials influences the strength and sign of synaptic plasticity. In this issue of Neuron, Sjöström and colleagues (2001) determine how this so-called spike timing-dependent plasticity depends on the frequency and strength of the presynaptic inputs.
Stuart
G J
GJ
John Curtin School of Medical Research, Australian National University, Canberra, Australia.
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000502:physiology*