Ugibohlin: a new dibromo-seco-isophakellin from Axinella carteri.
Chemical investigation of a marine sponge, Axinella carteri, collected on a reed slope of Talakanen Island, Phillipines, has afforded the new metabolite ugibohlin (1), along with its known cyclic derivative dibromoisophakellin (2). Structure elucidation of the isolated metabolites involved high-field 2D NMR spectroscopy including (1)H-(1)H COSY, HSQC, and HMBC. Revised chemical shift assignments are provided for 2.
Goetz
G H
GH
Pharmacia Corporation, 700 Chesterfield Parkway North, Chesterfield, Missouri 63198, USA. gilles.h.goetz@pharmacia.com
Harrigan
G G
GG
Likos
J
J
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010679:Philippines; D011161:Porifera / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000470:Alkaloids; D011758:Pyrroles; C446599:ugibohlin