title: Three cases of bacteremia caused by Vibrio cholerae O1 in Blantyre, Malawi.
abstract: We report three fatal cases of bacteremia (two adults, one neonate) caused by Vibrio cholerae O1 (Ogawa), which occurred in the context of a community outbreak of cholera diarrhea in Blantyre, Malawi. Only four cases of invasive disease caused by V. cholerae O1 have previously been reported. We describe the clinical features associated with these rare cases and discuss their significance.
authors.affiliation: Queen Elizabeth Central hospital, Blantyre, Malawi.
authors.forename: M A
authors.initials: MA
authors.lastname: Gordon
authors.forename: A L
authors.initials: AL
authors.lastname: Walsh
authors.forename: S R
authors.initials: SR
authors.lastname: Rogerson
authors.forename: K C
authors.initials: KC
authors.lastname: Magomero
authors.forename: C E
authors.initials: CE
authors.lastname: Machili
authors.forename: J E
authors.initials: JE
authors.lastname: Corkill
authors.forename: C A
authors.initials: CA
authors.lastname: Hart
mesh_terms: D000368:Aged; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology* / Q000503:physiopathology; D001426:Bacterial Proteins; D002771:Cholera / Q000453:epidemiology / Q000382:microbiology* / Q000503:physiopathology; D002772:Cholera Toxin / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology* / Q000503:physiopathology; D004196:Disease Outbreaks; D017809:Fatal Outcome; D005260:Female; D016680:Genome, Bacterial; D006801:Humans; D007231:Infant, Newborn; D008295:Malawi / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D014157:Transcription Factors / Q000235:genetics; D014734:Vibrio cholerae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D014157:Transcription Factors; C499324:toxR protein, Vibrio cholerae; C066719:toxR protein, bacteria; D002772:Cholera Toxin