Bioactive steroidal alkaloid glycosides from Solanum aculeastrum.
Solanum aculeastrum Dunal was investigated for the presence of molluscicidal compounds. This led to the isolation of solaculine A, from the root bark in addition to known steroidal alkaloids; solamargine and beta-solamarine from the berries. The structures were elucidated by spectroscopic techniques. Molluscicidal activity of the aqueous extracts of the berries and root bark, and the isolated compounds were investigated.
Wanyonyi
Alphonse W
AW
Chemistry Department, Kenyatta University, PO Box 43844, Nairobi, Kenya.
Chhabra
Sumesh C
SC
Mkoji
Gerald
G
Eilert
Udo
U
Njue
Wilson M
WM
D000818:Animals; D005638:Fruit / Q000737:chemistry; D008975:Molluscacides / Q000302:isolation & purification / Q000494:pharmacology*; D009844:Oligosaccharides / Q000302:isolation & purification / Q000494:pharmacology; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D012908:Snails / Q000187:drug effects*; D019657:Solanaceae / Q000737:chemistry*; D012991:Solanaceous Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D013256:Steroids / Q000302:isolation & purification / Q000494:pharmacology
D008975:Molluscacides; D009844:Oligosaccharides; D012991:Solanaceous Alkaloids; D013256:Steroids; C450167:solaculine A; C026609:beta-solamarine