Interferon therapy for orbital infiltration secondary to Erdheim-Chester disease.
OBJECTIVE
To describe a 55-year-old male with Erdheim-Chester disease with bilateral orbital infiltration and visual loss who was successfully treated with interferon-alpha.


METHODS
Interventional case report.


RESULTS
The patient was treated with interferon-alpha and had an improvement in his clinical signs, including his visual acuity, after 4 weeks of interferon therapy.


CONCLUSIONS
Interferon-alpha can be effective in the treatment of orbital infiltration secondary to Erdheim-Chester disease.
Esmaeli
B
B
Ophthalmology Section, Department of Plastic Surgery, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. besmaeli@mdanderson.org
Ahmadi
A
A
Tang
R
R
Schiffman
J
J
Kurzrock
R
R
D005094:Exophthalmos / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D006099:Granuloma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D010026:Osteosclerosis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate; D014792:Visual Acuity; D014973:Xanthomatosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
D016898:Interferon-alpha; D013669:Technetium Tc 99m Medronate