Pattern formation in the zebrafish retina.
During the past 15 years, the zebrafish has become established as a genetic model organism to study vertebrate development. It is particularly well suited for the analysis of the retina, and several genetic screens have yielded a large number of mutants affecting retinal development. Most of these mutants still await thorough analysis and molecular characterization, but work on a handful of genes has already generated interesting results that shed some light on patterning mechanisms employed in the vertebrate retina.
Neumann
C J
CJ
Developmental Biology Programme, EMBL, Meyerhofstrasse 1, Postfach 10.2209, D-69012 Heidelberg, Germany. carl.neumann@embl-heidelburg.de
D000818:Animals; D001341:Autonomic Nervous System / Q000196:embryology*; D019521:Body Patterning; D002454:Cell Differentiation; D053823:Hedgehog Proteins; D008565:Membrane Proteins / Q000378:metabolism; D023421:Models, Animal; D051880:Receptors, Notch; D012160:Retina / Q000196:embryology*; D015398:Signal Transduction; D015534:Trans-Activators / Q000235:genetics* / Q000502:physiology; D015027:Zebrafish / Q000196:embryology*
D053823:Hedgehog Proteins; D008565:Membrane Proteins; D051880:Receptors, Notch; D015534:Trans-Activators