title: Anti-mosquito ovary antibodies reduce the fecundity of Anopheles stephensi (Diptera:Insecta).
abstract: Rabbit antibodies to five antigens (AJ** 29, 35, 43, 64, and 80 kDa) derived from the ovaries of Anopheles stephensi tended to reduce the number of eggs produced. Ingestion of anti-mosquito ovary antibodies did not show a detectable effect on the mortality of mosquitoes. Antisera raised against An. stephensi ovaries showed cross-reactivity in other tissues and in the ovaries of other Anopheles spp. by Western blotting. The results indicate that anti-mosquito ovary antibodies have the potential to disrupt the reproductive physiology of mosquitoes, and indicate the need for further studies with target antigens.
authors.affiliation: Department of Biosciences, Maharshi Dayanand University, Rohtak 124001, Haryana, India. gakharsk@yahoo.co.in
authors.forename: S K
authors.initials: SK
authors.lastname: Gakhar
authors.forename: A
authors.initials: A
authors.lastname: Jhamb
authors.forename: M
authors.initials: M
authors.lastname: Gulia
authors.forename: R
authors.initials: R
authors.lastname: Dixit
mesh_terms: D000818:Animals; D000852:Anopheles / Q000276:immunology / Q000502:physiology*; D000906:Antibodies / Q000097:blood / Q000276:immunology*; D000941:Antigens / Q000276:immunology; D015153:Blotting, Western; D005247:Feeding Behavior; D005260:Female; D005298:Fertility; D010053:Ovary / Q000276:immunology; D011817:Rabbits
chemical_list: D000906:Antibodies; D000941:Antigens