Effect of three resuscitation procedures on respiratory and metabolic adaptation to extra uterine life in newborn calves.
The purpose of this study was to evaluate the effects of three resuscitation procedures on respiratory and metabolic adaptation to extra-uterine life during the first 24 h after birth in healthy newborn calves. Twenty-four newborn calves were randomly grouped into four categories: six calves did not receive any specific resuscitation procedure and were considered as controls (C); six received pharyngeal and nasal suctioning immediately after birth by use of a hand-powered vacuum pump (SUC); six received five litres of cold water poured over their heads immediately after birth (CW) and six were housed in a calf pen with an infrared radiant heater for 24 h after birth (IR). Calves were examined at birth, 5, 15, 30, 45 and 60 min, 2, 3, 6, 12 and 24 h after birth and the following measurements were recorded: physical and clinical examination, arterial blood gas analysis, pulmonary function tests using the oesophageal balloon catheter technique, arterial and venous blood acid-base balance analysis, jugular venous blood sampling for determination of metabolic, haematological and passive immune transfer variables. SUC was accompanied by improved pulmonary function efficiency and by a less pronounced decrease in body temperature. The "head shaking movement" and the subsequent temporary increase in total pulmonary resistance as well as the greater lactic acidosis due to CW were accompanied by more efficient, but statistically non-significant, pulmonary gas exchanges. IR allowed maintenance of higher body temperature without requiring increased catabolism of energetic stores. IR also caused a change in breathing pattern which contributed to better distribution of the ventilation and to slightly improved gas exchange. The results indicate that use of SUC, CW and IR modified respiratory and metabolic adaptation during the first 24 h after birth without side-effects. These resuscitation procedures should be recommended for their specific indication, i.e. cleansing of fetal fluid from upper airways, hypothermal stimulation of breathing and prevention of heat losses.
Uystepruyst
Ch
Ch
Laboratory for Functional Investigation, Department of Physiology, Faculty of Veterinary Medicine, University of Liège, Belgium. christophe.uysterprust@ulg.ac.be
Coghe
J
J
Dorts
Th
T
Harmegnies
N
N
Delsemme
M-H
MH
Art
T
T
Lekeux
P
P
D000136:Acid-Base Equilibrium; D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn / Q000097:blood / Q000276:immunology / Q000502:physiology*; D001784:Blood Gas Analysis / Q000662:veterinary; D002417:Cattle / Q000097:blood / Q000276:immunology / Q000502:physiology*; D003080:Cold Temperature; D006403:Hematologic Tests / Q000662:veterinary; D006358:Hot Temperature; D007116:Immunization, Passive / Q000662:veterinary; D011897:Random Allocation; D012129:Respiratory Function Tests / Q000662:veterinary; D015656:Respiratory Mechanics; D012151:Resuscitation / Q000379:methods / Q000662:veterinary*; D013396:Suction / Q000662:veterinary; D013997:Time Factors