title: Liver: single breath-hold dynamic subtraction CT with multi-detector row helical technology feasibility study.
abstract: Fifty-two patients with known or suspected hypervascular malignancy were examined to determine the technical feasibility of performing single-breath-hold dynamic subtraction computed tomography (CT) of the liver with multi-detector row helical CT. The precontrast and hepatic arterial CT scans, which were acquired during the same breath hold, were subtracted. The mean liver-to-muscle contrast ratio on the precontrast, hepatic arterial, and subtracted images was 1.3, 1.4, and 2.3, respectively. In 13 patients with lesions, the subtracted images showed a 2.5-fold increase in mean lesion contrast compared with the hepatic arterial CT scans.
authors.affiliation: Department of Radiology, Vancouver Hospital and Health Science Center, Vancouver, British Columbia, Canada.
authors.forename: Audrey L
authors.initials: AL
authors.lastname: Spielmann
authors.forename: Rendon C
authors.initials: RC
authors.lastname: Nelson
authors.forename: Carolyn R
authors.initials: CR
authors.lastname: Lowry
authors.forename: G Allan
authors.initials: GA
authors.lastname: Johnson
authors.forename: Gopal
authors.initials: G
authors.lastname: Sundaramoothy
authors.forename: Douglas H
authors.initials: DH
authors.lastname: Sheafor
authors.forename: Erik K
authors.initials: EK
authors.lastname: Paulson
mesh_terms: D000328:Adult; D000368:Aged; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging; D011446:Prospective Studies; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed / Q000379:methods*