title: Morphological coupling in development: lessons from prokaryotes.
abstract: At certain junctures in development, gene transcription is coupled to the completion of landmark morphological events. We refer to this dependence on morphogenesis for gene expression as "morphological coupling." Three examples of morphological coupling in prokaryotes are reviewed in which the activation of a transcription factor is tied to the assembly of a critically important structure in development.
authors.affiliation: Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
authors.forename: D Z
authors.initials: DZ
authors.lastname: Rudner
authors.forename: R
authors.initials: R
authors.lastname: Losick
mesh_terms: D000818:Animals; D001412:Bacillus subtilis / Q000166:cytology / Q000502:physiology; D018407:Bacterial Physiological Phenomena; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D018816:Genes, cdc; D009024:Morphogenesis / Q000502:physiology*; D012098:Reproduction / Q000235:genetics / Q000502:physiology; D012808:Sigma Factor / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D013171:Spores, Bacterial / Q000502:physiology
chemical_list: D012808:Sigma Factor