title: Comparing pressures required to abolish snoring and sleep apnea.
abstract: OBJECTIVE
  Snoring and obstructive sleep apnea share similar pathogenesis and similar response to treatment with continuous positive airway pressure (CPAP). The purpose of this study was to compare pressures required to abolish apneas (POSA) with pressures required to abolish snoring (PSNOR).
  
  
  METHODS
  Cross-sectional, nonrandomized cohort study.
  
  
  METHODS
  Sleep disorders clinic at St Michael's Hospital - a tertiary referral centre and a teaching hospital of the University of Toronto, Toronto, Ontario.
  
  
  METHODS
  Unselected consecutive 441 patients with confirmed sleep apnea who were undergoing a CPAP titration study in the sleep laboratory.
  
  
  METHODS
  Nocturnal polysomnography using CPAP titration protocol, which required incremental increases in pressure until snoring and apnea were abolished or a maximum pressure of 16 cm H2O was attained. PSNOR and POSA were recorded and compared.
  
  
  RESULTS
  Mean (+/- SD) pressures required to abolish snoring and apnea were: PSNOR 8.3+/-2.57 cm H2O and POSA 7.9+/-2.72 cm H2O (P<0.0001). In 75% of patients, the PSNOR was within +/-1 cm H2O of the POSA; in 92%, it was within +/-2 cm H2O; and in 97%, it was within +/-3 cm H2O.
  
  
  CONCLUSIONS
  Empirically increasing pressure by 2 cm H2O in patients on CPAP who continue to snore may abolish snoring and apnea without the necessity of another titration study.
authors.affiliation: University of Toronto, Toronto, Canada. victor.hoffstein@utoronto.ca
authors.forename: V
authors.initials: V
authors.lastname: Hoffstein
authors.forename: Z
authors.initials: Z
authors.lastname: Oliver
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011175:Positive-Pressure Respiration / Q000379:methods*; D012891:Sleep Apnea Syndromes / Q000503:physiopathology / Q000517:prevention & control*; D012913:Snoring / Q000503:physiopathology / Q000517:prevention & control*; D016896:Treatment Outcome