title: Lithium neurotoxicity.
abstract: Inspite of the advent of newer antimanic drugs, lithium carbonate remains widely used in the treatment and prevention of manic-depressive illness. However care has to be exercised due to its low therapeutic index. The central nervous system and renal system are predominantly affected in acute lithium intoxication and is potentially lethal. The more common side effect involves the central nervous system. It occurs early and is preventable. We describe three cases of lithium toxicity admitted to Johor Bahru Hospital, with emphasis on its neurological preponderance.
authors.affiliation: Department of Psychiatry, Hospital Sultanah Aminah, Johor Bahru.
authors.forename: Y
authors.initials: Y
authors.lastname: Suraya
authors.forename: K Y
authors.initials: KY
authors.lastname: Yoong
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000506:poisoning*; D001714:Bipolar Disorder / Q000188:drug therapy; D002493:Central Nervous System Diseases / Q000139:chemically induced; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced; D016651:Lithium Carbonate / Q000506:poisoning*; D008875:Middle Aged; D009498:Neurotoxins
chemical_list: D000928:Antidepressive Agents; D009498:Neurotoxins; D016651:Lithium Carbonate