title: Cloning and expression analysis of chicken Lix1, a founding member of a novel gene family.
abstract: Limb Expression 1 (Lix1), a founding member of a novel gene family, was identified in a screen for genes transiently and locally expressed during early chicken limb development. Most prominently, Lix1 is transiently expressed in the nascent hindlimb bud between Hamburger-Hamilton stages 15 and 19. Chicken Lix1 transcripts are also found in the basal plate of rhombomeres 3 and 5, in pharyngeal and in foregut mesenchyme and in all facial primordia except for the mandibular arches. Homologs of chick Lix1 exist in human, mouse and Drosophila.
authors.affiliation: Max Planck Institute for Experimental Endocrinology, Foedor-Lynen Strasse 7, 30625, Hannover, Germany.
authors.forename: E C
authors.initials: EC
authors.lastname: Swindell
authors.forename: C
authors.initials: C
authors.lastname: Moeller
authors.forename: C
authors.initials: C
authors.lastname: Thaller
authors.forename: G
authors.initials: G
authors.lastname: Eichele
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000071183:Autophagy-Related Proteins; D002642:Chick Embryo; D003001:Cloning, Molecular; D004330:Drosophila; D020224:Expressed Sequence Tags; D005145:Face / Q000196:embryology; D006614:Hindlimb / Q000196:embryology; D006801:Humans; D008648:Mesoderm / Q000378:metabolism; D051379:Mice; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D017434:Protein Structure, Tertiary; D011506:Proteins; D012333:RNA, Messenger / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D000071183:Autophagy-Related Proteins; C499180:Lix1 protein, mouse; D011506:Proteins; D012333:RNA, Messenger