Hydroxysesamone and 2,3-epoxysesamone from roots of Sesamum indicum.
A red naphthoquinone, named hydroxysesamone, was isolated from the roots of Sesamum indicum together with a known yellow naphthoxirene derivative, 2,3-epoxy-2,3-dihydro-5,8-dihydroxy-2-(3-methyl-2-butenyl)-1,4-naphthoquinone, named 2,3-epoxysesamone. The structure of the naphthoquinone was characterized as 2,5,8-trihydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone on the basis of spectral evidence. Full assignments of NMR resonances of 2,3-epoxysesamone were also confirmed by two-dimensional NMR spectroscopic experiments. Chlorosesamone, hydroxysesamone and 2,3-epoxysesamone all showed antifungal activities toward Cladosporium fulvum.
Hasan
A F
AF
Department of Biochemistry and Food Science, Faculty of Agriculture, Kagawa University, Kagawa 761-0795, Japan.
Furumoto
T
T
Begum
S
S
Fukui
H
H
D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002963:Cladosporium / Q000187:drug effects; D004852:Epoxy Compounds / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D009285:Naphthoquinones / Q000737:chemistry* / Q000302:isolation & purification; D029601:Pedaliaceae / Q000737:chemistry*
C447010:2,3-epoxysesamone; D000935:Antifungal Agents; D004852:Epoxy Compounds; D009285:Naphthoquinones; C447009:hydroxysesamone