title: MDB: the Metalloprotein Database and Browser at The Scripps Research Institute.
abstract: The Metalloprotein Database and Browser (MDB; http://metallo.scripps.edu) at The Scripps Research Institute is a web-accessible resource for metalloprotein research. It offers the scientific community quantitative information on geometrical parameters of metal-binding sites in protein structures available from the Protein Data Bank (PDB). The MDB also offers analytical tools for the examination of trends or patterns in the indexed metal-binding sites. A user can perform interactive searches, metal-site structure visualization (via a Java applet), and analysis of the quantitative data by accessing the MDB through a web browser without requiring an external application or platform-dependent plugin. The MDB also has a non-interactive interface with which other web sites and network-aware applications can seamlessly incorporate data or statistical analysis results from metal-binding sites. The information contained in the MDB is periodically updated with automated algorithms that find and index metal sites from new protein structures released by the PDB.
authors.affiliation: The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Jesus M
authors.initials: JM
authors.lastname: Castagnetto
authors.forename: Sean W
authors.initials: SW
authors.lastname: Hennessy
authors.forename: Victoria A
authors.initials: VA
authors.lastname: Roberts
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Getzoff
authors.forename: John A
authors.initials: JA
authors.lastname: Tainer
authors.forename: Michael E
authors.initials: ME
authors.lastname: Pique
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D003196:Computer Graphics; D003628:Database Management Systems; D030562:Databases, Protein; D016247:Information Storage and Retrieval; D020407:Internet; D008024:Ligands; D008667:Metalloproteins / Q000737:chemistry* / Q000378:metabolism; D008670:Metals / Q000378:metabolism; D014584:User-Computer Interface
chemical_list: D008024:Ligands; D008667:Metalloproteins; D008670:Metals