title: Absence of ST7 mutations in tumor-derived cell lines and tumors.
abstract: The gene ST7 has been proposed as the multi-tissue tumor-suppressor gene (TSG) at chromosome 7q31.1. However, we have sought and failed to detect the truncating mutations reported to exist in this gene.
authors.affiliation: The Cancer Research Campaign Laboratories, Beatson Institute for Cancer Research, Switchback Road, Bearsden, Glasgow, G61 1BD, UK.
authors.forename: K A
authors.initials: KA
authors.lastname: Hughes
authors.forename: A F
authors.initials: AF
authors.lastname: Hurlstone
authors.forename: E S
authors.initials: ES
authors.lastname: Tobias
authors.forename: R
authors.initials: R
authors.lastname: McFarlane
authors.forename: D M
authors.initials: DM
authors.lastname: Black
mesh_terms: D002897:Chromosomes, Human, Pair 7; D016147:Genes, Tumor Suppressor; D006801:Humans; D019656:Loss of Heterozygosity; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation; D018807:Polymorphism, Single-Stranded Conformational; D014407:Tumor Cells, Cultured
chemical_list: D008565:Membrane Proteins