title: Zeaxanthin and menaquinone-7 biosynthesis in Sphingobacterium multivorum via the methylerythritol phosphate pathway.
abstract: Feeding of [1-(13)C]glucose, [U-(13)C(6)]glucose, [3-(13)C]alanine and [1-(13)C]acetate to Sphingobacterium multivorum showed that this bacterium utilizes the methylerythritol phosphate pathway for the biosynthesis of menaquinone-7 and zeaxanthin, a carotenoid of industrial importance. Differential incorporation of the labeled precursors gave some insight into the preferred carbon sources involved in isoprenoid biosynthesis.
authors.affiliation: Université Louis Pasteur/CNRS, Institut Le Bel, Strasbourg Cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Rosa-Putra
authors.forename: A
authors.initials: A
authors.lastname: Hemmerlin
authors.forename: J
authors.initials: J
authors.lastname: Epperson
authors.forename: T J
authors.initials: TJ
authors.lastname: Bach
authors.forename: L H
authors.initials: LH
authors.lastname: Guerra
authors.forename: M
authors.initials: M
authors.lastname: Rohmer
mesh_terms: D000085:Acetates / Q000378:metabolism; D000409:Alanine / Q000378:metabolism; D002070:Butadienes / Q000737:chemistry / Q000378:metabolism; D002247:Carbon Isotopes / Q000378:metabolism; D004896:Erythritol / Q000031:analogs & derivatives* / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000254:growth & development / Q000378:metabolism*; D045782:Hemiterpenes; D010420:Pentanes; D024482:Vitamin K 2 / Q000031:analogs & derivatives* / Q000378:metabolism*; D024341:Xanthophylls; D065146:Zeaxanthins; D019207:beta Carotene / Q000031:analogs & derivatives* / Q000096:biosynthesis*
chemical_list: D000085:Acetates; D002070:Butadienes; D002247:Carbon Isotopes; D045782:Hemiterpenes; D010420:Pentanes; D024341:Xanthophylls; D065146:Zeaxanthins; D019207:beta Carotene; C005059:isoprene; D024482:Vitamin K 2; C062629:menaquinone 7; D005947:Glucose; D000409:Alanine; D004896:Erythritol