title: Efficacy and cost-effectiveness of bronchial arterial embolisation in the treatment of major haemoptysis.
abstract: OBJECTIVE
  To determine the efficacy and cost-effectiveness of bronchial artery embolisation (BAE) in the treatment of major and massive haemoptysis in HIV-positive and negative patients with pulmonary inflammatory disease.
  
  
  METHODS
  A retrospective review of patients admitted over a period of 24 months to Wentworth Hospital with major haemoptysis treated using BAE.
  
  
  RESULTS
  Eighty-seven patients were treated (77 males, 10 females). Bilateral disease was present in 50 patients (57%). Thirty-two patients were HIV-positive (37%). Embolisation was successfully performed in 77 patients (88.5%), and failed for technical reasons in 10 patients (11.5%). There was only one procedural complication. Fifty-seven patients had a successful outcome, with cessation of haemoptysis within 24 hours (66.5%). Haemoptysis continued in 30 patients (34%) (20 patients embolised and the 10 patients who had failed procedures). Fourteen of these patients (16%) required lobectomy or pneumonectomy as an emergency procedure. Five patients (5.7%) died from respiratory failure or pulmonary haemorrhage. Twenty-four HIV-positive patients were successfully embolised. Costing of BAE, including a 2-day ICU and 3-day ward stay, was R6,720; together with surgical resection the cost was R14,170.
  
  
  CONCLUSIONS
  BAE is an effective treatment for major and/or massive haemoptysis in patients with pulmonary inflammatory disease who are not surgical candidates. Patients who are HIV-positive are able to tolerate the procedure well.
authors.affiliation: Department of Radiology, Wentworth Hospital, University of Natal, Durban.
authors.forename: P
authors.initials: P
authors.lastname: Corr
authors.forename: D
authors.initials: D
authors.lastname: Blyth
authors.forename: C
authors.initials: C
authors.lastname: Sanyika
authors.forename: D
authors.initials: D
authors.lastname: Royston
mesh_terms: D000328:Adult; D001981:Bronchial Arteries; D003362:Cost-Benefit Analysis; D004621:Embolization, Therapeutic / Q000191:economics / Q000379:methods*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006469:Hemoptysis / Q000628:therapy*; D006801:Humans; D008297:Male; D011013:Pneumonectomy; D011014:Pneumonia / Q000150:complications*; D012189:Retrospective Studies; D016896:Treatment Outcome