Microtubules, motors, and mRNA localization mechanisms: watching fluorescent messages move.
Proper spatial and temporal localization of specific mRNAs is pivotal in the early stages of development. To dissect the mechanisms of localization, several groups are employing advanced fluorescence microscopy to track RNA movements in live oocytes and embryos.
Saxton
W M
WM
Department of Biology, Indiana University, Bloomington, IN 47405, USA.
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D004330:Drosophila / Q000196:embryology* / Q000254:growth & development; D005456:Fluorescent Dyes / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism*; D020409:Molecular Motor Proteins / Q000378:metabolism*; D009865:Oocytes / Q000502:physiology*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*
D005456:Fluorescent Dyes; D020409:Molecular Motor Proteins; D012333:RNA, Messenger