Role of lipopolysaccharide susceptibility in the innate immune response to Salmonella typhimurium infection: LPS, a primary target for recognition of Gram-negative bacteria.
Lipopolysaccharide is an important recognition marker by virtue of which the innate immune system senses and reacts against Gram-negative bacteria invading the LPS susceptible host. This review deals with the factors affecting LPS susceptibility and with the role of the latter in the course and outcome of Salmonella typhimurium infection.
Freudenberg
M A
MA
Max Planck Institute for Immunobiology, Stübeweg 51, 79 108 Freiburg i. Breisgau, Germany. freudenberg@immunbio.mpg.de
Merlin
T
T
Gumenscheimer
M
M
Kalis
C
C
Landmann
R
R
Galanos
C
C
D000818:Animals; D006090:Gram-Negative Bacteria / Q000276:immunology / Q000472:pathogenicity; D006801:Humans; D007113:Immunity, Innate; D008070:Lipopolysaccharides / Q000276:immunology* / Q000378:metabolism / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D012481:Salmonella Infections, Animal / Q000276:immunology* / Q000382:microbiology; D012486:Salmonella typhimurium / Q000276:immunology / Q000472:pathogenicity*
D008070:Lipopolysaccharides