title: [Cellular surgery with laser in ophthalmology. A review].
abstract: This is a review of a number of laser methods, allowing to realize strongly localized, atraumatic, molecular, cellular, and subcellular microeffects. New instruments are the laser tweezers and the laser knife to be used with a microscope (microscopical surgery). Laser tweezers allow fixation, by means of the radiation pressure of molecular, cellular, and subcellular elements, of diameters as small as 1 microm. These may be irradiated atraumatically by means of short-pulsed lasers. A reversible damage of the cell membrane allows to introduce living genetic material into living cells and to reversibly modify their genetic behaviour. Micromanipulation/irradiation of living cells by means of the short-pulse laser method of living cells may be optimal in in-vivo fertilization experiments. Short-pulse laser methods have been tentatively introduced in ophthalmology and highly localized effects have been realized in the trabecular meshwork for the treatment of glaucoma and in the retina in retinal pathology.
authors.affiliation: Lindenhofspital, CH Bern.
authors.forename: F
authors.initials: F
authors.lastname: Fankhauser
mesh_terms: D006801:Humans; D053685:Laser Therapy; D013508:Ophthalmologic Surgical Procedures / Q000295:instrumentation / Q000379:methods*; D009885:Ophthalmology / Q000639:trends