[Experimental pathobiochemistry research of the knee joint fluid of ice hockey players and alpine skiers after sport injuries].
26 knee joint fluids, conditioned by injuries, of ice hockey players and alpine skiers had been analysed. The examination of the joint fluids were followed by 17 biochemical parameters, which were fixed before. The analysis of synovial fluid allows a differentiation between an inflamed and non-inflamed process. As a measure for the inflamed enzymatic potence appears the increase of the PMN-Elastase-Concentration with a relative lack of alpha1-Antitrypsin. The proteolytic potence of the PMN-Elastase is additional intensified by the parallel increase of the LDH-Activity and therewith linked to the oxidative tissue damage. Consequently, the altered synovial fluid of traumatised knee joints is an important factor of posttraumatic damage of cartilage. The biochemical analysis of traumatised knee joint fluids heads to identify these enzymes and therewith linked to the chance of treatment with appropriate enzyme inhibitiors. This leads to a reduction or even partly to a prevention of traumatised damage of cartilages.
Büttner
E
E
Praxis für Allgemein- und Sportmedizin, München Schwabing. www.sportmed.de.
Gröger
A
A
Burghart
R
R
D000293:Adolescent; D000328:Adult; D001182:Arthroscopy; D002358:Cartilage, Articular / Q000293:injuries; D003627:Data Interpretation, Statistical; D003937:Diagnosis, Differential; D006688:Hockey / Q000293:injuries*; D006801:Humans; D007124:Immunoenzyme Techniques; D007718:Knee Injuries / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008297:Male; D010196:Pancreatic Elastase / Q000032:analysis; D012106:Research; D012865:Skiing / Q000293:injuries*; D013582:Synovial Fluid / Q000201:enzymology / Q000378:metabolism*; D000515:alpha 1-Antitrypsin / Q000032:analysis
D000515:alpha 1-Antitrypsin; D007770:L-Lactate Dehydrogenase; D010196:Pancreatic Elastase