Implementing randomization procedures in the asthma clinical research network.
Randomization is a required component for the success of most controlled clinical trials. To ensure that the benefits of randomization are realized, well defined and carefully planned procedures must be put in place prior to the start of a trial. This paper presents a detailed account of the registration and randomization procedures implemented for the first four clinical trials of the Asthma Clinical Research Network.
Kunselman
S J
SJ
Department of Health Evaluation Sciences, College of Medicine, Pennsylvania State University, Hershey, PA 17033-0855, USA.
Armstrong
T J
TJ
Britton
T B
TB
Forand
P E
PE
D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000420:Albuterol / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011786:Quality Control; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012106:Research; D000068299:Salmeterol Xinafoate
D000318:Adrenergic beta-Agonists; D000068299:Salmeterol Xinafoate; D000420:Albuterol