title: Chromatic contrast thresholds as a prognostic test for visual improvement after macular hole surgery: color vision and macular hole surgery outcome.
abstract: OBJECTIVE
  To evaluate the relationship between preoperative chromatic contrast thresholds, postoperative visual acuities (VA), and visual improvement after macular hole surgery.
  
  
  METHODS
  A consecutive series of patients with Stage II to IV macular holes was studied before macular hole surgery. Preoperative chromatic contrast thresholds, VA, and reading acuity were analyzed in relation to the postoperative visual function. The chromatic contrast thresholds were measured using a computerized cathode ray tube-based system along red-green and tritan confusion axes.
  
  
  RESULTS
  Preoperative and postoperative chromatic contrast thresholds were elevated significantly in affected eyes (P < 0.001). Preoperative VA showed a strong correlation with postoperative VA (r = 0.66, P < 0.001) but a weak correlation with visual improvement (r = -0.33, P = 0.03). Red-green contrast threshold correlated strongly with both the distance visual improvement (r = -0.77, P < 0.001) and reading visual improvement (r = -0.61, P < 0.001). Tritan contrast threshold, however, showed a slightly weaker correlation (distance: r = -0.63, P < 0.001; reading: r = -0.47, P < 0.005).
  
  
  CONCLUSIONS
  These results suggest that chromatic contrast thresholds, especially the red-green contrast threshold, represent a better prognostic guide for visual improvement after macular hole surgery than VA measurement.
authors.affiliation: Vision Research Department, Sussex Eye Hospital, Brighton, United Kingdom.
authors.forename: W K
authors.initials: WK
authors.lastname: Poon
authors.forename: G L
authors.initials: GL
authors.lastname: Ong
authors.forename: L G
authors.initials: LG
authors.lastname: Ripley
authors.forename: A G
authors.initials: AG
authors.lastname: Casswell
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003118:Color Perception / Q000502:physiology*; D003119:Color Perception Tests; D015350:Contrast Sensitivity / Q000502:physiology*; D019773:Epiretinal Membrane / Q000601:surgery; D005260:Female; D005466:Fluorocarbons / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016684:Prone Position; D011446:Prospective Studies; D012167:Retinal Perforations / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012684:Sensory Thresholds / Q000502:physiology; D016896:Treatment Outcome; D014821:Vitrectomy
chemical_list: D005466:Fluorocarbons; C042852:perflutren