title: Study of retrieved acetabular sockets made from high-dose, cross-linked polyethylene.
abstract: Although ultra-high molecular weight polyethylene (UHMWPE) has stable chemical properties, chemical degradation, such as oxidation reaction, progresses with long-term clinical use. The purpose of this study was to investigate the change in properties of polyethylene (PE) in vivo by examining retrieved UHMWPE sockets and high-dose, cross-linked PE (100 Mrad PE) sockets. Twenty retrieved sockets (including 2 100 Mrad PE sockets), which were implanted from 1970 to 1996, were used for analysis. The oxidation index of 100 Mrad PE sockets was approximately the same as that of the normal UHMWPE sockets in worn areas. These long-term clinical results indicate that 100 Mrad PE is sufficiently stable for clinical use and that free radicals would not affect progression of oxidation significantly.
authors.affiliation: H. Oonishi Memorial Joint Replacement Institute, Tominaga Hospital, Osaka-shi, Japan. oons-h@ga2.so-net.ne.jp
authors.forename: H
authors.initials: H
authors.lastname: Oonishi
authors.forename: I C
authors.initials: IC
authors.lastname: Clarke
authors.forename: S
authors.initials: S
authors.lastname: Masuda
authors.forename: H
authors.initials: H
authors.lastname: Amino
mesh_terms: D000077:Acetabulum; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals / Q000737:chemistry; D006622:Hip Prosthesis; D006801:Humans; D010084:Oxidation-Reduction; D011095:Polyethylenes / Q000737:chemistry*
chemical_list: D005609:Free Radicals; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene