title: Alterations of systolic left ventricular twist after acute myocardial infarction.
abstract: We sought to characterize the alterations of left ventricular (LV) twist after acute myocardial infarction in humans and to study their relationship to usual parameters of LV function. Systolic LV twist was measured by color tissue Doppler echocardiography (TDE) in 34 patients after anterior myocardial infarction and in 20 controls. In a subset of controls and patients, the assessment of LV twist by TDE was validated against magnetic resonance (MR) tissue tagging with good agreement between the two methods. Myocardial ischemia was responsible for a decrease in LV twist in infarct patients (P < 0.01). The decrease in LV twist was correlated with the extent of the asynergic area and global LV function as assessed by LV cineangiography (P < 0.001). Thus acute myocardial ischemia is responsible for a decrease in LV twist that is related to global LV function. Color TDE is a promising technique for straightforward assessment of LV twist in humans.
authors.affiliation: Fédération de Cardiologie, Henri Mondor University Hospital, 51 Av du Mal De Lattre de Tassigny, 94010 Créteil, France. jgarot@free.fr
authors.forename: Jérôme
authors.initials: J
authors.lastname: Garot
authors.forename: Olivier
authors.initials: O
authors.lastname: Pascal
authors.forename: Benoît
authors.initials: B
authors.lastname: Diébold
authors.forename: Geneviève
authors.initials: G
authors.lastname: Derumeaux
authors.forename: Bernhard L
authors.initials: BL
authors.lastname: Gerber
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Dubois-Randé
authors.forename: João A C
authors.initials: JA
authors.lastname: Lima
authors.forename: Pascal
authors.initials: P
authors.lastname: Guéret
mesh_terms: D000208:Acute Disease; D003971:Diastole / Q000502:physiology; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology*; D010210:Papillary Muscles / Q000503:physiopathology*; D012016:Reference Values; D012907:Smoking; D013599:Systole / Q000502:physiology*; D016277:Ventricular Function, Left / Q000502:physiology*