title: Plasmodium falciparum: pfcrt and DHFR mutations are associated with failure of chloroquine plus proguanil prophylaxis in travelers.
authors.forename: R
authors.initials: R
authors.lastname: Durand
authors.forename: S
authors.initials: S
authors.lastname: Jafari
authors.forename: O
authors.initials: O
authors.lastname: Bouchaud
authors.forename: P
authors.initials: P
authors.lastname: Ralaimazava
authors.forename: A
authors.initials: A
authors.lastname: Keundjian
authors.forename: J
authors.initials: J
authors.lastname: Le Bras
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000494:pharmacology / Q000627:therapeutic use*; D002738:Chloroquine / Q000494:pharmacology / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology / Q000517:prevention & control*; D008565:Membrane Proteins / Q000235:genetics*; D026901:Membrane Transport Proteins; D009154:Mutation; D010963:Plasmodium falciparum / Q000187:drug effects / Q000235:genetics*; D002727:Proguanil / Q000494:pharmacology / Q000627:therapeutic use*; D015800:Protozoan Proteins; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics*; D014195:Travel; D017211:Treatment Failure
chemical_list: D000962:Antimalarials; D008565:Membrane Proteins; D026901:Membrane Transport Proteins; C416369:PfCRT protein, Plasmodium falciparum; D015800:Protozoan Proteins; D002738:Chloroquine; D013762:Tetrahydrofolate Dehydrogenase; D002727:Proguanil