title: [General intravenous anesthesia with spontaneous respiration for noncavitary interventions in cancer].
abstract: Two new variants of total intravenous anesthesia with spontaneous respiration were used in 307 female patients subjected to noncavitary interventions for cancer and gynecological cancer. The patients were divided into 2 groups: 1) total anesthesia with midasolam, fentanyl, and calipsol and 2) the same + propofol. Preventive analgesia by preoperative injections of peripheral analgesics was carried out in both groups. Both methods proved to be effective, ensuring good protection from traumatic noncavitary oncological operations. Balanced anesthesia with two hypnotics midasolam and propofol should be preferred, as they mutually potentiate their effects and therefore can be used in the minimum doses, thus preventing the probable side effects, minimizing the use of central analgesics, and ruling out the probability of respiration depression.
authors.forename: V E
authors.initials: VE
authors.lastname: Khoronenko
authors.forename: N A
authors.initials: NA
authors.lastname: Osipova
authors.forename: V V
authors.initials: VV
authors.lastname: Petrova
authors.forename: I E
authors.initials: IE
authors.lastname: Sergeeva
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Donskova
authors.forename: N V
authors.initials: NV
authors.lastname: Zhelezkina
authors.forename: L M
authors.initials: LM
authors.lastname: Ivanova
mesh_terms: D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous / Q000379:methods*; D000778:Anesthetics, Dissociative / Q000008:administration & dosage / Q000494:pharmacology; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000494:pharmacology; D001943:Breast Neoplasms / Q000601:surgery*; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage / Q000494:pharmacology; D008197:Lymph Node Excision; D015409:Mastectomy, Radical; D015412:Mastectomy, Segmental; D008874:Midazolam / Q000008:administration & dosage / Q000494:pharmacology; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000601:surgery*
chemical_list: D000778:Anesthetics, Dissociative; D018686:Anesthetics, Intravenous; D007649:Ketamine; D008874:Midazolam; D005283:Fentanyl; D015742:Propofol