title: Cherubism and its charlatans.
abstract: Cherubism is a rare hereditary condition characterised by progressive cystic proliferation of the mandible and maxilla in childhood, followed by post-pubertal involution of the process and jaw remodelling in adulthood. Its name is derived from the cherubic appearance that results from the jaw hypertrophy. Here, we present the case of a young boy with cherubism, in the context of his pedigree, to illustrate the clinical characteristics and their variable expression. We also seek to distinguish cherubism from central giant cell granuloma and giant cell tumour of the jaws, with which it holds a false synonymity.
authors.affiliation: The Craniofacial and Plastic Surgery Department, Temple Street Children's Hospital, Dublin, Ireland.
authors.forename: D A
authors.initials: DA
authors.lastname: Lannon
authors.forename: M J
authors.initials: MJ
authors.lastname: Earley
mesh_terms: D002116:Calcitonin / Q000627:therapeutic use; D002636:Cherubism / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D002648:Child; D003937:Diagnosis, Differential; D018212:Giant Cell Tumor of Bone / Q000175:diagnosis / Q000188:drug therapy; D006101:Granuloma, Giant Cell / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007571:Jaw Diseases / Q000175:diagnosis / Q000188:drug therapy; D007573:Jaw Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D010375:Pedigree; D019651:Plastic Surgery Procedures / Q000379:methods*
chemical_list: D002116:Calcitonin