Partial sequence analysis of indigenous hepatitis E virus isolated in the United Kingdom.
The first nucleotide sequences of hepatitis E virus (HEV) acquired in the United Kingdom are described. The sequences are novel and are related most closely to HEV isolated from Greece (Greece 2 strain), consistent with their having been derived from an indigenous European virus. HEV was assumed until recently to be rare in the United Kingdom and other industrialised countries and, consequently, hepatitis E may be under-diagnosed in industrialised countries.
Wang
Y
Y
Centre for Hepatology, Royal Free and University College Medical School, University College London, London, United Kingdom.
Levine
D F
DF
Bendall
R P
RP
Teo
C G
CG
Harrison
T J
TJ
D005838:Genotype; D016751:Hepatitis E / Q000821:virology*; D016752:Hepatitis E virus / Q000145:classification / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D013997:Time Factors; D006113:United Kingdom