title: The PROSITE database, its status in 2002.
abstract: PROSITE [Bairoch and Bucher (1994) Nucleic Acids Res., 22, 3583-3589; Hofmann et al. (1999) Nucleic Acids Res., 27, 215-219] is a method of identifying the functions of uncharacterized proteins translated from genomic or cDNA sequences. The PROSITE database (http://www.expasy.org/prosite/) consists of biologically significant patterns and profiles designed in such a way that with appropriate computational tools it can rapidly and reliably help to determine to which known family of proteins (if any) a new sequence belongs, or which known domain(s) it contains.
authors.affiliation: Swiss Institute of Bioinformatics, Swiss Institute for Experimental Cancer Research (ISREC), CH-1066 Epalinges /Lausanne, Switzerland.
authors.forename: Laurent
authors.initials: L
authors.lastname: Falquet
authors.forename: Marco
authors.initials: M
authors.lastname: Pagni
authors.forename: Philipp
authors.initials: P
authors.lastname: Bucher
authors.forename: Nicolas
authors.initials: N
authors.lastname: Hulo
authors.forename: Christian J A
authors.initials: CJ
authors.lastname: Sigrist
authors.forename: Kay
authors.initials: K
authors.lastname: Hofmann
authors.forename: Amos
authors.initials: A
authors.lastname: Bairoch
mesh_terms: D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D000818:Animals; D003628:Database Management Systems; D030562:Databases, Protein; D005544:Forecasting; D016247:Information Storage and Retrieval; D020407:Internet; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D016415:Sequence Alignment
chemical_list: D011506:Proteins