title: Therapy of postoperative stroke: report of intra-arterial thrombolysis of a hyperacute embolic stroke 5 days following CABG.
abstract: Intra-arterial (IA) recombinant tissue plasminogen activator (rt-PA) is an investigational treatment for acute stroke. We report a case of IA thrombolysis of a hyperacute middle cerebral artery stroke 5 days after coronary artery bypass graft surgery. Despite a serious extracranial bleeding complication (hemothorax), immediate thrombolysis with IA rt-PA led to near complete resolution of the neurological deficit and a favorable outcome.
authors.affiliation: Section of Neurology, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA. khasani@medscape.com
authors.forename: S
authors.initials: S
authors.lastname: Khasani
authors.forename: S R
authors.initials: SR
authors.lastname: Ramee
authors.forename: R A
authors.initials: RA
authors.lastname: Felberg
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000188:drug therapy* / Q000209:etiology*; D007261:Infusions, Intra-Arterial; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology*; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D010959:Tissue Plasminogen Activator