title: Three new dihydroisocoumarins from the Greek endemic species Scorzonera cretica.
abstract: Extracts of the Greek endemic species Scorzonera cretica afforded three new compounds, the dihydroisocoumarin scorzocreticin (1) and its glycosides, scorzocreticoside I (2) and scorzocreticoside II (3), as well as 11 known compounds. The structures of the isolated compounds were elucidated on the basis of spectral data and chemical methods. The absolute configurations of 1-3 were established using circular dichroism.
authors.affiliation: Division of Pharmacognosy, School of Pharmacy, University of Athens, Panepistimioupolis Zografou, GR-15771 Athens, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Paraschos
authors.forename: P
authors.initials: P
authors.lastname: Magiatis
authors.forename: E
authors.initials: E
authors.lastname: Kalpoutzakis
authors.forename: C
authors.initials: C
authors.lastname: Harvala
authors.forename: A L
authors.initials: AL
authors.lastname: Skaltsounis
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D002845:Chromatography; D002942:Circular Dichroism; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006115:Greece; D006868:Hydrolysis; D049934:Isocoumarins; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009793:Ochratoxins / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
chemical_list: D003374:Coumarins; D006027:Glycosides; D049934:Isocoumarins; D009793:Ochratoxins; C446581:scorzocreticin; C446582:scorzocreticoside I; C446583:scorzocreticoside II; C120538:ochracin