The use of low-power laser irradiation for faster vascularization of tissue transplants.
We studied the effect of low-power laser irradiation on vascularization and take of transplanted rabbit renal and pancreatic tissue in athymic nude mice. The mean size of the transplant and the number of blood vessels in it were higher in irradiated mice compared to nonirradiated controls. Moreover, the organ-specific structure of the transplants was preserved in irradiated mice, but not in the control group. These findings suggest that low-power laser irradiation can be used for promotion of vascularization and take of tissue transplants.
Revazova
E
E
N. N. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow.
Sorokina
Y
Y
Bryzgalov
I
I
Sebastian
J
J
Keller
G
G
Ivanov
A
A
Watson
J
J
D000818:Animals; D016030:Kidney Transplantation / Q000379:methods*; D051379:Mice; D008819:Mice, Nude; D018919:Neovascularization, Physiologic / Q000528:radiation effects*; D016035:Pancreas Transplantation / Q000379:methods; D011817:Rabbits; D013997:Time Factors