title: The Salmonella pathogenicity island-1 type III secretion system.
abstract: Salmonella pathogenicity island 1 (SPI1) encodes a type III secretion system that is required for virulence during the intestinal phase of infection. The expression of SPI1 genes is controlled by many global regulatory pathways that affect the expression/activity of transcriptional regulators encoded on SPI1.
authors.affiliation: Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA.
authors.forename: C P
authors.initials: CP
authors.lastname: Lostroh
authors.forename: C A
authors.initials: CA
authors.lastname: Lee
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D007422:Intestines / Q000382:microbiology; D051379:Mice; D012481:Salmonella Infections, Animal / Q000382:microbiology*; D012486:Salmonella typhimurium / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity*; D015398:Signal Transduction
chemical_list: D001426:Bacterial Proteins; C419942:Spi1 protein, Salmonella