title: Treatment of postcatheterisation false aneurysms: ultrasound-guided compression vs ultrasound-guided thrombin injection.
abstract: OBJECTIVE
  to compare the efficacy and cost-effectiveness of ultrasound-guided compression (UGC) with ultrasound-guided thrombin injection (UGTI) for treatment of postcatheterisation arterial false aneurysms (cFA).
  
  
  METHODS
  prospective clinical study using historical controls.
  
  
  METHODS
  we prospectively collected data on 33 consecutive patients diagnosed with cFA larger than 1.5 cm in diameter. These were treated with UGTI. We performed a retrospective review of data on a former group of 33 consecutive historical control patients that were treated by UGC.
  
  
  RESULTS
  the groups were similar in respect of demographic and clinical variables. Thirty patients were suitable for UGC and 33 patients were suitable for UGTI. The success rate for UGC was 26/30 (87%) compared to 33/33 (100%) for UGTI (p<0.05). Thrombosis was achieved during the first treatment session in 7/26 patients treated by UGC, compared to 26/33 in the UGTI group (p<0.0001). Four patients that failed UGC and two patients that were unsuitable for UGC required surgical repair. UGTI as compared to UGC was shorter in duration (25 vs 75 min) and required no sedation. No thromboembolic or systemic complications occurred in either group. Cost analysis revealed savings of $US 517 for each patient treated by UGTI as compared with UGC.
  
  
  CONCLUSIONS
  in our study, UGTI is superior to UGC, and we suggest that UGTI should become the procedure of choice for the treatment of cFA.
authors.affiliation: Department of Vascular Surgery, Assaf Harofeh Medical Center, Zerifin 70300, Israel.
authors.forename: E E
authors.initials: EE
authors.lastname: Weinmann
authors.forename: D
authors.initials: D
authors.lastname: Chayen
authors.forename: Z V
authors.initials: ZV
authors.lastname: Kobzantzev
authors.forename: M
authors.initials: M
authors.lastname: Zaretsky
authors.forename: A
authors.initials: A
authors.lastname: Bass
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D002406:Catheterization, Peripheral / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000293:injuries; D006489:Hemostatic Techniques; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D011312:Pressure; D011446:Prospective Studies; D013917:Thrombin / Q000008:administration & dosage*; D018084:Ultrasonography, Interventional
chemical_list: D006490:Hemostatics; D013917:Thrombin