NRTI induced mitochondrial toxicity as a mechanism for HAART related lipodystrophy: fact or fiction?
Walker
U A
UA
Medizinische Universitätsklinik, Freiburg, Germany and Onze Lieve Vrouwe Gasthuis, Amsterdam, the Netherlands. uwalker@mm61.ukl.uni-freiburg.de
Brinkman
K
K
D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D004272:DNA, Mitochondrial / Q000187:drug effects* / Q000378:metabolism; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D008060:Lipodystrophy / Q000139:chemically induced* / Q000503:physiopathology*; D008928:Mitochondria / Q000187:drug effects* / Q000378:metabolism; D018894:Reverse Transcriptase Inhibitors / Q000009:adverse effects*
D004272:DNA, Mitochondrial; D018894:Reverse Transcriptase Inhibitors