Constituents of Lepidium meyenii 'maca'.
The tubers of Lepidium meyenii contain the benzylated derivative of 1,2-dihydro-N-hydroxypyridine, named macaridine, together with the benzylated alkamides (macamides), N-benzyl-5-oxo-6E,8E-octadecadienamide and N-benzylhexadecanamide, as well as the acyclic keto acid, 5-oxo-6E,8E-octadecadienoic acid. The structure elucidation of the isolated compounds was based primarily on 1D and 2D NMR spectroscopic analyses, including 1H-1H COSY, 1H-13C HMQC, 1H-13C HMBC and 1H-1H NOESY experiments, as well as from 1H-15N NMR HMBC correlations for macaridine and N-benzylhexadecanamide.
Muhammad
Ilias
I
National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, University MS 38677, USA. milias@sunset.backbone.olemiss.edu
Zhao
Jianping
J
Dunbar
D Chuck
DC
Khan
Ikhlas A
IA
D000577:Amides / Q000737:chemistry / Q000302:isolation & purification*; D029686:Lepidium / Q000737:chemistry*; D053284:Polyunsaturated Alkamides; D011725:Pyridines / Q000737:chemistry / Q000302:isolation & purification*
D000577:Amides; C450177:N-benzyl-5-oxo-6,8-octadecadienamide; D053284:Polyunsaturated Alkamides; D011725:Pyridines; C450176:macaridine; C450178:N-benzylhexadecanamide