title: Eosinophilic cystitis in a 4-year-old boy: successful long-term treatment with cyclosporin A.
abstract: A 4-year-old Jewish boy presented with dysuria, urinary dribbling, increased urinary frequency, and new onset of diurnal enuresis. An infiltrating solid mass involving the entire bladder wall was found. Biopsy revealed "tumor-forming" eosinophilic cystitis, a rare bladder lesion of unclear cause. Antitoxocariasis treatment was unsuccessful. High-dose corticosteroids failed. The child's clinical condition and bladder sonographic findings continued to deteriorate. Treatment with cyclosporin A was given for 8 months, with a complete clinical, radiologic, and histopathologic cure and no side effects. Two years of follow-up showed a complete recovery.
authors.affiliation: Department of Pediatrics, Meir General Hospital, Sapir Medical Center, Kfar Saba, Israel. avip2@clalit.org.il
authors.forename: A
authors.initials: A
authors.lastname: Pomeranz
authors.forename: A
authors.initials: A
authors.lastname: Eliakim
authors.forename: Y
authors.initials: Y
authors.lastname: Uziel
authors.forename: G
authors.initials: G
authors.lastname: Gottesman
authors.forename: V
authors.initials: V
authors.lastname: Rathaus
authors.forename: T
authors.initials: T
authors.lastname: Zehavi
authors.forename: B
authors.initials: B
authors.lastname: Wolach
mesh_terms: D002675:Child, Preschool; D016572:Cyclosporine / Q000627:therapeutic use*; D003556:Cystitis / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D004802:Eosinophilia / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine