The structures of antioxidant and cytotoxic agents from natural source: anthraquinones and tannins from roots of Rumex patientia.
A new anthraquinone glycoside, emodin-6-O-beta-D-glucopyranoside, and a new simple halogenated flavan-3-ol, 6-chlorocatechin, have been isolated from the roots of Rumex patientia L. together with seven known phenolic compounds. Their structures were elucidated on the basis of spectroscopic methods. Cytotoxic effects and radical scavenging properties of the isolated compounds have been demonstrated.
Demirezer
L O
LO
Faculty of Pharmacy, Department of Pharmacognosy, Hacettepe University, TR-06100 Ankara, Turkey. omurd@hacettepe.edu.tr
Kuruüzüm-Uz
A
A
Bergere
I
I
Schiewe
H J
HJ
Zeeck
A
A
D000880:Anthraquinones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D019664:Polygonaceae / Q000737:chemistry*; D013634:Tannins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000880:Anthraquinones; D000975:Antioxidants; D013634:Tannins