title: An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia.
abstract: The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.
authors.affiliation: Department of Anatomy, College of Medicine, The Catholic University of Korea, Seoul 137-701, South Korea.
authors.forename: Mun-Yong
authors.initials: MY
authors.lastname: Lee
authors.forename: Yun-Sik
authors.initials: YS
authors.lastname: Choi
authors.forename: Jeong-Sun
authors.initials: JS
authors.lastname: Choi
authors.forename: Do Sik
authors.initials: DS
authors.lastname: Min
authors.forename: Myung-Hoon
authors.initials: MH
authors.lastname: Chun
authors.forename: Ok Nyu
authors.initials: ON
authors.lastname: Kim
authors.forename: Sang Bok
authors.initials: SB
authors.lastname: Lee
authors.forename: Seong Yun
authors.initials: SY
authors.lastname: Kim
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000737:chemistry; D050957:HSP110 Heat-Shock Proteins; D006360:Heat-Shock Proteins / Q000032:analysis*; D006624:Hippocampus / Q000737:chemistry* / Q000166:cytology; D007150:Immunohistochemistry; D002546:Ischemic Attack, Transient / Q000378:metabolism*; D008297:Male; D017966:Pyramidal Cells / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D050957:HSP110 Heat-Shock Proteins; D006360:Heat-Shock Proteins; C494655:Hspa4 protein, rat