title: [The role of yaws in the serologic screening of treponematoses in blood donors in Martinique].
abstract: Using TPHA instead of VDRL for syphilis blood-screening since 1995 showed an important increase of positive blood donors in Martinique. Yaws, another treponema disease, has been present on the island until 1975-1980. Usual tests are unable to identify which type--venereal or non venereal--of treponema is involved. Our study, carried out from January 1995 to May 1999, compares actual serological and epidemiological characteristics of TPHA reactive donors to former studies. In our results, the frequency of reactive TPHA is about 1.04% in blood donations. Donors are carrying serological tracks of a past treponema disease with very low rate of antibodies, sometimes linked to yaws. Among donors aged 18 to 30, prevalence is low and is going to become similar to the rate observed in Continental France. This means that this problem will disappear in new donor generations. We suggest the possibility for them to continue blood donation, if their personal preliminary enquiry fits the admission criteria for blood giving.
authors.affiliation: Etablissement français du sang, hôpital Pierre-Zobda Quitman, BP 666, 97261, Fort-de-France, Martinique.
authors.forename: H
authors.initials: H
authors.lastname: Maier
authors.forename: R
authors.initials: R
authors.lastname: Césaire
authors.forename: O
authors.initials: O
authors.lastname: Bera
authors.forename: B
authors.initials: B
authors.lastname: Kerob-Bauchet
authors.forename: A K
authors.initials: AK
authors.lastname: Ould Amar
authors.forename: N
authors.initials: N
authors.lastname: Desbois
authors.forename: G
authors.initials: G
authors.lastname: Follea
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001782:Blood Donors / Q000706:statistics & numerical data*; D002308:Cardiolipins / Q000097:blood; D002784:Cholesterol / Q000097:blood; D003429:Cross Reactions; D003937:Diagnosis, Differential; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008395:Martinique / Q000453:epidemiology; D008403:Mass Screening / Q000706:statistics & numerical data*; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D010713:Phosphatidylcholines / Q000097:blood; D011446:Prospective Studies; D012189:Retrospective Studies; D016036:Seroepidemiologic Studies; D013045:Species Specificity; D013587:Syphilis / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control; D013588:Syphilis Serodiagnosis / Q000379:methods; D014210:Treponema pallidum / Q000276:immunology; D015001:Yaws / Q000175:diagnosis* / Q000453:epidemiology
chemical_list: D000913:Antibodies, Protozoan; D002308:Cardiolipins; D010713:Phosphatidylcholines; C054448:VDRL antigen; D002784:Cholesterol