title: Human herpesvirus 6-associated hemophagocytic syndrome in a healthy adult.
abstract: Virus-associated hemophagocytic syndrome is a fulminant disorder associated with systemic viral infection and characterized pathologically by multiple-organ infiltration of hemophagocytic histiocytes into the lymphoreticular tissues. This is the first report of a previously healthy adult in whom Human herpesvirus 6 reactivation induced this syndrome with severe hemodynamic and respiratory distress.
authors.affiliation: Department of Traumatology, Osaka University Medical School, 2-15, Yamadaoka, Suita-shi, Osaka, 565-0871, Japan. tanaka@hp-emerg.med.osaka-u.ac.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tanaka
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Nishimura
authors.forename: Mikiko
authors.initials: M
authors.lastname: Hakui
authors.forename: Hisashi
authors.initials: H
authors.lastname: Sugimoto
authors.forename: Keiko
authors.initials: K
authors.lastname: Tanaka-Taya
authors.forename: Koichi
authors.initials: K
authors.lastname: Yamanishi
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D004912:Erythrocytes / Q000276:immunology* / Q000821:virology; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage; D015654:Herpesvirus 6, Human / Q000276:immunology*; D006644:Histiocytes / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008297:Male; D010198:Pancytopenia; D010587:Phagocytosis; D012128:Respiratory Distress Syndrome / Q000821:virology*; D019349:Roseolovirus Infections / Q000175:diagnosis* / Q000276:immunology / Q000503:physiopathology; D013577:Syndrome
chemical_list: D000914:Antibodies, Viral; D016179:Granulocyte Colony-Stimulating Factor