Absence of ST7 mutations in tumor-derived cell lines and tumors.
The gene ST7 has been proposed as the multi-tissue tumor-suppressor gene (TSG) at chromosome 7q31.1. However, we have sought and failed to detect the truncating mutations reported to exist in this gene.
Hughes
K A
KA
The Cancer Research Campaign Laboratories, Beatson Institute for Cancer Research, Switchback Road, Bearsden, Glasgow, G61 1BD, UK.
Hurlstone
A F
AF
Tobias
E S
ES
McFarlane
R
R
Black
D M
DM
D002897:Chromosomes, Human, Pair 7; D016147:Genes, Tumor Suppressor; D006801:Humans; D019656:Loss of Heterozygosity; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation; D018807:Polymorphism, Single-Stranded Conformational; D014407:Tumor Cells, Cultured
D008565:Membrane Proteins