title: Novel conversion of 1,2-disubstituted cis-epoxides to one-carbon homologated allylic alcohols using dimethylsulfonium methylide.
abstract: [reaction: see text] The treatment of cis-epoxides with an excess of dimethylsulfonium methylide affords one-carbon homologated allylic alcohols in good to excellent yields.
authors.affiliation: Department of Medicinal Chemistry, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leics, LE11 5RH, United Kingdom. lilian.alcaraz@astrazeneca.com
authors.forename: L
authors.initials: L
authors.lastname: Alcaraz
authors.forename: A
authors.initials: A
authors.lastname: Cridland
authors.forename: E
authors.initials: E
authors.lastname: Kinchin