title: Survivors of childhood cancers: implications for obstetric anaesthesia.
abstract: Treatment of many childhood malignancies involves surgery, radiotherapy and chemotherapy. If the child survives, normal physical development can be impaired and abnormalities with anaesthetic implications may be present. We discuss two women with a range of problems who presented for obstetric anaesthesia, having survived childhood malignancies. Common features included anthracycline cardiotoxicity and short stature. Both patients received incremental spinal anaesthesia in order to titrate the dose of local anaesthetic required to produce an adequate block height and to minimize cardiovascular instability.
authors.affiliation: Academic Unit of Anaesthesia, Leeds General Infirmary, UK.
authors.forename: H
authors.initials: H
authors.lastname: Gorton
authors.forename: R
authors.initials: R
authors.lastname: Wilson
authors.forename: A
authors.initials: A
authors.lastname: Robinson
authors.forename: G
authors.initials: G
authors.lastname: Lyons
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects; D002585:Cesarean Section; D002648:Child; D005260:Female; D006130:Growth Disorders / Q000150:complications / Q000209:etiology; D006331:Heart Diseases / Q000139:chemically induced; D006801:Humans; D007223:Infant; D009369:Neoplasms / Q000628:therapy*; D011247:Pregnancy; D017741:Survivors
chemical_list: D000903:Antibiotics, Antineoplastic