title: Modulation of presbycusis: current status and future directions.
abstract: Literature and ideas are reviewed concerning the modulation of presbycusis - the influence of variables that can alter the severity and/or time course of presbycusis or counteract its negative aspects. Eleven topics are identified: variables related to biological aging; genetics; noise-induced hearing loss; moderately augmented acoustic environment; neural plasticity and the central auditory system; neural plasticity and hearing aids; socioeconomic and cultural barriers to hearing aid use; lifestyle (diet, exercise, etc.); medical variables; pharmaceutical interventions for presbycusis, and cognitive variables. It is concluded that the field of otogerontology will best be served by a comprehensive, integrative interaction among basic researchers and clinical scientists who will continue to learn how the auditory problems associated with presbycusis can be intentionally modulated in beneficial ways.
authors.affiliation: Department of Psychology, The Jackson Laboratory, Bar Harbor, ME, USA. jimw@niu.edu
authors.forename: J F
authors.initials: JF
authors.lastname: Willott
authors.forename: T
authors.initials: T
authors.lastname: Hnath Chisolm
authors.forename: J J
authors.initials: JJ
authors.lastname: Lister
mesh_terms: D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology; D000818:Animals; D003072:Cognition Disorders / Q000150:complications; D003469:Culture; D005260:Female; D006310:Hearing Aids; D006317:Hearing Loss, Noise-Induced / Q000150:complications / Q000503:physiopathology / Q000534:rehabilitation; D006801:Humans; D008297:Male; D009473:Neuronal Plasticity / Q000502:physiology; D011304:Presbycusis / Q000150:complications / Q000503:physiopathology* / Q000534:rehabilitation; D051381:Rats; D012720:Severity of Illness Index; D012907:Smoking / Q000009:adverse effects; D014815:Vitamins
chemical_list: D014815:Vitamins