title: Septum formation in Aspergillus nidulans.
abstract: Filamentous fungi form multicellular hyphae that are partitioned by septa. In A. nidulans, septum formation requires the assembly of a septal band following the completion of mitosis. Recent observations show that this band is a dynamic structure composed of actin, a septin and a formin. In addition, assembly is dependent upon a conserved protein kinase cascade that regulates mitotic exit and septation in yeast. Hyphal differentiation may reflect the regulation of this cascade by cyclin-dependent kinase activity. In this review, the dynamics and regulation underlying the assembly of the septal band are discussed.
authors.affiliation: Plant Science Initiative, N234 Beadle Center, University of Nebraska, Lincoln, NE 68588-0660, USA. sharri1@unlnotes.unl.edu
authors.forename: S D
authors.initials: SD
authors.lastname: Harris
mesh_terms: D001233:Aspergillus nidulans / Q000235:genetics / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D018844:Cyclin-Dependent Kinases / Q000378:metabolism
chemical_list: D018844:Cyclin-Dependent Kinases