title: SPiD: a subtilis protein interaction database.
abstract: BACKGROUND
  Protein-protein interactions are a potential source of valuable clues in determining the functional role of as yet uncharacterized gene products in metabolic pathways. Graph-like structures emerging from the accumulation of interaction data make it difficult to maintain a consistent and global overview by hand. Bioinformatics tools are needed to perform this graph visualization while maintaining a link to the experimental data.
  
  
  RESULTS
  "SPiD" is an online database for exploring networks of interacting proteins in Bacillus subtilis characterized by the two-hybrid system. Graphical displays of interaction networks are created dynamically as users interactively navigate through these networks. Third party applications can interface the database through a Common Object Request Broker Architecture (CORBA) tier.
  
  
  BACKGROUND
  SPiD is available through its web site at http://www-mig.versailles.inra.fr/bdsi/SPiD, and through an Interoperable Object Reference (IOR) and its associated Interface Definition Language (IDL).
  
  
  BACKGROUND
  hoebeke@versailles.inra.fr
authors.affiliation: Unité Mathématique, Informatique & Génome, INRA CRV, Route de St. Cyr, F-78026 Versailles Cedex, France. hoebeke@versailles.inra.fr
authors.forename: M
authors.initials: M
authors.lastname: Hoebeke
authors.forename: H
authors.initials: H
authors.lastname: Chiapello
authors.forename: P
authors.initials: P
authors.lastname: Noirot
authors.forename: P
authors.initials: P
authors.lastname: Bessières
mesh_terms: D001412:Bacillus subtilis / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D030562:Databases, Protein; D020407:Internet; D020798:Two-Hybrid System Techniques
chemical_list: D001426:Bacterial Proteins