title: Diet and exercise in type 2 diabetes mellitus.
abstract: The question is no longer whether diet and exercise can benefit the individual with type 2 diabetes. Rather, the type and duration of exercise the magnitude of the effects on glycemic control, insulin sensitivity, and on risk factors for cardiovascular disease must be considered in determining the feasibility and acceptability of an intervention program. It is now clear that regular physical exercise is important in both the prevention and treatment of type 2 diabetes. The benefits of exercise are many and include increased energy expenditure, which, combined with dietary restriction, leads to decreased body fat, increased insulin sensitivity, improved long-term glycemic control, improved lipid profiles, lower blood pressure, and increased cardiovascular fitness. Persons with type 2 diabetes often find it difficult to exercise and are at increased risk for injury or exacerbation of underlying diseases or diabetic complications. Therefore, before starting an exercise program, all patients with type 2 diabetes should have a complete history and physical examination, with particular attention to evaluation of cardiovascular disease, medications that may affect glycemic control during or after exercise, and diabetic complications including retinopathy, nephropathy, and neuropathy. Exercise programs should be designed to start slowly, build up gradually, and emphasize moderately intense exercise performed at least three times a week and preferably five to seven times a week for best results.
authors.affiliation: Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: O
authors.initials: O
authors.lastname: Hamdy
authors.forename: L J
authors.initials: LJ
authors.lastname: Goodyear
authors.forename: E S
authors.initials: ES
authors.lastname: Horton
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000502:physiology; D001794:Blood Pressure; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology* / Q000517:prevention & control; D004032:Diet; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009004:Monosaccharide Transport Proteins / Q000502:physiology
chemical_list: D001786:Blood Glucose; D008055:Lipids; D009004:Monosaccharide Transport Proteins