Somatotopic organization of the medial wall of the cerebral hemispheres: a 3 Tesla fMRI study.
Somatotopic organization of the human medial wall of the cerebral hemispheres was studied using functional MRI conducted at high field strength (3 T) with fine spatial resolution ( approximately 2 mm). Healthy subjects performed paced, repetitive movements of the fingers and toes. Within the supplementary motor area (SMA), two regions were identified: finger movements activated a region rostral and superior to that for toe movements. Two activation foci were also identified in the cingulate motor area: toe movements activated a region rostral and ventral to that activated by finger movements. All foci were located between the anterior and posterior commissures. Our results confirm previous human and non-human primate studies regarding the rostral-caudal organization of the SMA and CMA. The dorsal-ventral organization of the CMA, however, appears to be divergent from results derived from cortical stimulation studies conducted in non-human primates.
Mayer
A R
AR
Section of Neuropsychology, Department of Neurology, Medical College of Wisconsin, 9200 W. Wisconsin Ave., Milwaukee, WI 53226, USA.
Zimbelman
J L
JL
Watanabe
Y
Y
Rao
S M
SM
D000328:Adult; D001931:Brain Mapping; D005260:Female; D005385:Fingers / Q000294:innervation* / Q000502:physiology; D006179:Gyrus Cinguli / Q000033:anatomy & histology* / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000033:anatomy & histology* / Q000502:physiology; D009068:Movement / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology; D014034:Toes / Q000294:innervation* / Q000502:physiology