title: Clinical and experimental observation of glistening in acrylic intraocular lenses.
abstract: OBJECTIVE
  To determine whether or not glistening particles in implanted acrylic intraocular lenses (IOL) increase with the passage of time.
  
  
  METHODS
  Prospective clinical study: Glistenings were evaluated in 31 patients (49 eyes) with implanted acrylic IOL, the emphasis being on when glistening first became evident and subsequent changes in the number of glistening particles.
  
  
  METHODS
  IOLs were monitored for any changes that occurred with the passage of time as they were immersed first in a 50 degrees C saline solution and then in another saline solution with a temperature of 35 degrees C.
  
  
  RESULTS
  Prospective clinical study: Glistening phenomenon was observed in 28 IOLs (57%) 2 to 16 months after implantation (mean = 6.6 months). Glistenings reached their peak in number within a few months of formation in all cases, showing no further increase thereafter.
  
  
  METHODS
  Glistening particles first appeared on the 10th day of the experiment in sizes ranging from 3 to 10 microm in diameter. They remained at the same level for the next 60 days without showing any increase.
  
  
  CONCLUSIONS
  Glistening formation in acrylic IOLs was found to stabilize within a few months after appearance. The method of our experiment proved reliable in producing, in a relatively short period of time, glistening similar to that found in patients.
authors.affiliation: Miyata Eye Clinic, Hiroshima-shi, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Miyata
authors.forename: N
authors.initials: N
authors.lastname: Uchida
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: S
authors.initials: S
authors.lastname: Yaguchi
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000150:complications; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D011475:Prosthesis Failure; D013997:Time Factors; D014617:Vacuoles / Q000473:pathology*
chemical_list: D000180:Acrylic Resins