title: Cedronolactone E, a novel C(19) quassinoid from Simaba cedron.
abstract: A novel pentacyclic C(19) quassinoid, cedronolactone E (1), was isolated from the wood of Simaba cedron. Its structure was elucidated by interpretation of spectroscopic data.
authors.affiliation: Tokyo University of Pharmacy and Life Science, 1432-1 Horihouchi, Hachioji, Tokyo 192-0392, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hitotsuyanagi
authors.forename: A
authors.initials: A
authors.lastname: Ozeki
authors.forename: H
authors.initials: H
authors.lastname: Itokawa
authors.forename: S
authors.initials: S
authors.lastname: de Mello Alves
authors.forename: K
authors.initials: K
authors.lastname: Takeya
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001938:Brazil; D002853:Chromatography, Liquid; D004354:Drug Screening Assays, Antitumor; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D007941:Leukemia P388; D051379:Mice; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D036702:Quassins; D029641:Simaroubaceae / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014934:Wood
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D006576:Heterocyclic Compounds, 4 or More Rings; D036702:Quassins; C446584:cedronolactone E