Parotid and submandibular/sublingual salivary flow during high dose radiotherapy.
It was studied whether differences in acute radiosensitivity exist between parotid and submandibular/sublingual glands. The results revealed that salivary flow rates decreased dramatically during the first 2 weeks of radiotherapy. Neither recovery nor significant differences were observed between the production of saliva from the parotid and submandibular/sublingual glands during the 13 weeks observation period.
Burlage
F R
FR
Department of Radiotherapy, University Hospital, P.O. Box 30.0019700 RB, Groningen, The Netherlands.
Coppes
R P
RP
Meertens
H
H
Stokman
M A
MA
Vissink
A
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012469:Salivary Glands / Q000528:radiation effects*; D012472:Salivation / Q000528:radiation effects*; D014987:Xerostomia / Q000150:complications