title: Pleural small cell carcinoma in pre-existent asbestos related pleural disease.
abstract: Extrapulmonary small cell carcinoma (SCC) is a very rare disease, and a primary pleural manifestation is extremely rare. A case of SCC of the pleura in a 66-year-old man with pre-existent asbestos-related pleural plaques is presented. This is the first case of pleural SCC in a patient with asbestos-induced pleural disease and the third reported case of a pleural SCC. The SCC developed in an area with pre-existent pleural thickening, underlining the need for careful analysis of alterations in the manifestation of pleural disease in patients with asbestos exposition.
authors.affiliation: Department of Pulmonary Diseases, University Medical Center, St. Radboud, Nijmegen, The Netherlands. h.vanderheijden@long.azn.nl
authors.forename: H F M
authors.initials: HF
authors.lastname: van der Heijden
authors.forename: Y F
authors.initials: YF
authors.lastname: Heijdra
authors.forename: J
authors.initials: J
authors.lastname: Bulten
authors.forename: J
authors.initials: J
authors.lastname: Festen
mesh_terms: D000368:Aged; D001194:Asbestos / Q000009:adverse effects*; D018288:Carcinoma, Small Cell / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D010994:Pleura / Q000000981:diagnostic imaging / Q000473:pathology*; D010997:Pleural Neoplasms / Q000209:etiology* / Q000503:physiopathology; D012907:Smoking / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D001194:Asbestos