Nosocomial endocarditis caused by Corynebacterium amycolatum and other nondiphtheriae corynebacteria.
The nondiphtheriae corynebacteria are uncommon but increasingly recognized as agents of endocarditis in patients with underlying structural heart disease or prosthetic-valves. We describe three cases of nosocomial endocarditis caused by nondiphtheriae corynebacteria, including the first reported case of Corynebacterium amycolatum, endocarditis. These all occurred in association with indwelling intravascular devices.
Knox
Karen L
KL
Department of Microbiology, 1st Floor Jenner Wing, St. George's Hospital, Cranmer Terrace, Tooting, London SW17 0RE, UK. kknox@sghms.ac.uk
Holmes
Alison H
AH
D000368:Aged; D002408:Catheters, Indwelling / Q000009:adverse effects / Q000382:microbiology; D003352:Corynebacterium / Q000302:isolation & purification / Q000472:pathogenicity*; D003354:Corynebacterium Infections / Q000188:drug therapy / Q000382:microbiology*; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D012293:Rifampin / Q000627:therapeutic use; D014640:Vancomycin / Q000627:therapeutic use
D014640:Vancomycin; D012293:Rifampin