title: Synthesis of new pryridyl alcohols and their use as catalysts in the asymmetric addition of diethylzinc to aldehydes.
abstract: Optically active new pyridyl alcohols 1-4, which can be easily synthesized by the reaction of (+)-camphor or (-)-menthone with lithiated pyridine derivatives, were applied as chiral ligands in the asymmetric addition of diethylzinc to aldehydes. Good yields with up to 94.0% enantiomeric excesses were observed in these reactions.
authors.affiliation: Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P.R. China.
authors.forename: Qianyong
authors.initials: Q
authors.lastname: Xu
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Wu
authors.forename: Xinfu
authors.initials: X
authors.lastname: Pan
authors.forename: Albert S C
authors.initials: AS
authors.lastname: Chan
authors.forename: Teng-Kuei
authors.initials: TK
authors.lastname: Yang