title: Sonographic detection of multiple brain abscesses in a newborn with IgA deficiency.
abstract: We report the case of a neonate with selective IgA deficiency and multiple brain abscesses diagnosed with sonography. Brain sonography revealed multiple abscesses in the left hemisphere; the abscesses ranged from 10 to 20 mm. Cultures obtained from the cerebrospinal fluid and blood were positive for Proteus mirabilis. The neonate responded promptly to broad-spectrum antibiotic therapy and had no neurologic sequelae. Because IgA deficiency is associated with infections, we believe it was a predisposing factor for the brain abscesses.
authors.affiliation: Pediatric Clinic, University of Rijeka, Children's Hospital Kantrida, Istarska Street 43, HR-51000 Rijeka, Croatia.
authors.forename: V
authors.initials: V
authors.lastname: Rozmanić
authors.forename: V
authors.initials: V
authors.lastname: Ahel
authors.forename: S
authors.initials: S
authors.lastname: Dessardo
authors.forename: S
authors.initials: S
authors.lastname: Flajsman-Raspor
authors.forename: J
authors.initials: J
authors.lastname: Franulović
authors.forename: M
authors.initials: M
authors.lastname: Gazdik
mesh_terms: D001922:Brain Abscess / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D017098:IgA Deficiency / Q000150:complications*; D007070:Immunoglobulin A / Q000134:cerebrospinal fluid; D007231:Infant, Newborn; D008297:Male; D011512:Proteus Infections / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D011513:Proteus mirabilis / Q000302:isolation & purification; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D007070:Immunoglobulin A