Sventrin, a new bromopyrrole alkaloid from the Caribbean sponge Agelas sventres.
A detailed analysis of the secondary metabolites of a specimen of Agelas sventres was carried out here for the first time. The chemistry of Agelas sponges is dominated by bromopyrrole derivatives. Besides three known bromopyrrole metabolites, a new compound, sventrin (1), was isolated and its structure identified using spectroscopic methods. Sventrin (1) was shown to be a feeding deterrent compound against a common omnivorous reef fish.
Assmann
M
M
Alfred-Wegener-Institut für Polar- und Meeresforschung, Am Handelshafen 12, D-27570 Bremerhaven, Germany..
Zea
S
S
Köck
M
M
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D001444:Bahamas; D002264:Carboxylic Acids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D005247:Feeding Behavior / Q000187:drug effects; D005399:Fishes; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
C446563:4,5-dibromopyrrole-2-carboxylic acid; D000470:Alkaloids; D002264:Carboxylic Acids; D011758:Pyrroles; C446562:sventrin; C050529:hymenidin; C077209:oroidin