SPiD: a subtilis protein interaction database.
BACKGROUND
Protein-protein interactions are a potential source of valuable clues in determining the functional role of as yet uncharacterized gene products in metabolic pathways. Graph-like structures emerging from the accumulation of interaction data make it difficult to maintain a consistent and global overview by hand. Bioinformatics tools are needed to perform this graph visualization while maintaining a link to the experimental data.


RESULTS
"SPiD" is an online database for exploring networks of interacting proteins in Bacillus subtilis characterized by the two-hybrid system. Graphical displays of interaction networks are created dynamically as users interactively navigate through these networks. Third party applications can interface the database through a Common Object Request Broker Architecture (CORBA) tier.


BACKGROUND
SPiD is available through its web site at http://www-mig.versailles.inra.fr/bdsi/SPiD, and through an Interoperable Object Reference (IOR) and its associated Interface Definition Language (IDL).


BACKGROUND
hoebeke@versailles.inra.fr
Hoebeke
M
M
Unité Mathématique, Informatique & Génome, INRA CRV, Route de St. Cyr, F-78026 Versailles Cedex, France. hoebeke@versailles.inra.fr
Chiapello
H
H
Noirot
P
P
Bessières
P
P
D001412:Bacillus subtilis / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D030562:Databases, Protein; D020407:Internet; D020798:Two-Hybrid System Techniques
D001426:Bacterial Proteins