title: Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample.
abstract: The comorbidity of current and lifetime DSM-IV anxiety and mood disorders was examined in 1,127 outpatients who were assessed with the Anxiety Disorders Interview Schedule for DSM-IV: Lifetime version (ADIS-IV-L). The current and lifetime prevalence of additional Axis I disorders in principal anxiety and mood disorders was found to be 57% and 81%, respectively. The principal diagnostic categories associated with the highest comorbidity rates were mood disorders, posttraumatic stress disorder (PTSD), and generalized anxiety disorder (GAD). A high rate of lifetime comorbidity was found between the anxiety and mood disorders; the lifetime association with mood disorders was particularly strong for PTSD, GAD, obsessive-compulsive disorder, and social phobia. The findings are discussed in regard to their implications for the classification of emotional disorders.
authors.affiliation: Center for Anxiety and Related Disorders, Boston University, Massachusetts 02215-2013, USA. tabrown@bu.edu
authors.forename: T A
authors.initials: TA
authors.lastname: Brown
authors.forename: L A
authors.initials: LA
authors.lastname: Campbell
authors.forename: C L
authors.initials: CL
authors.lastname: Lehman
authors.forename: J R
authors.initials: JR
authors.lastname: Grisham
authors.forename: R B
authors.initials: RB
authors.lastname: Mancill
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000175:diagnosis / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index