title: ['Benign' meningioma].
abstract: Meningioma was diagnosed in four women, aged 40, 24, 41 and almost 75 years, respectively. The first of these patients was treated with surgery, the second and third patients underwent surgery followed by conventional radiotherapy because of a tumour residue or dural tail, and the last patient was treated with stereotactic radiosurgery. They recovered well and were followed by means of regular outpatient check-ups. Twenty percent of all primary brain tumours are meningiomas, over 90% of which are benign. Nevertheless, a large hospital-based population study showed a 5-year survival rate of only 70%. Microsurgery is usually the treatment of first choice. However, in about 25% of cases, excision is incomplete and tumour growth almost always continues. Further surgery influences prognosis unfavourably. New sophisticated radiation techniques help to control tumour progression in about 80-90% of cases. This success, however, may be associated with new cranial nerve deficits or panhypopituitarism. Prospective, comparative studies are not available.
authors.affiliation: Afd. Neurochirurgie, Erasmus Universitair Medisch Centrum, Postbus 2040, 3000 CA Rotterdam. wolbers@neuro.fgg.eur.nl
authors.forename: J G
authors.initials: JG
authors.lastname: Wolbers
authors.forename: C J
authors.initials: CJ
authors.lastname: Avezaat
authors.forename: P J
authors.initials: PJ
authors.lastname: Nowak
authors.forename: J M
authors.initials: JM
authors.lastname: Kros
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001929:Brain Edema / Q000209:etiology / Q000517:prevention & control; D003399:Craniotomy; D003907:Dexamethasone / Q000627:therapeutic use; D004827:Epilepsy / Q000209:etiology; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008579:Meningioma / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008866:Microsurgery; D018365:Neoplasm, Residual; D016634:Radiosurgery; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D003907:Dexamethasone