title: Enantiomeric separation of drugs and herbicides on a beta-cyclodextrin-bonded stationary phase.
abstract: A chemically bonded beta-cyclodextrin chiral stationary phase for HPLC was prepared in a "one pot" process by the reaction of a phenylated beta-cyclodextrin with silica gel. Various racemic analytes such as drugs (aminoalcohol adrenergic beta-blockers, benzodiazepine anxiolytics, arylpropionic acid antiinflammatory agents) and herbicides (aryloxypropionic acids and esters) were separated on the prepared material. The column showed good chiral recognition ability for most of the solutes tested when using heptane and either 2-propanol or chloroform as organic mobile phase modifiers.
authors.affiliation: Laboratoire d' Analyse Organique Fonctionnelle, Faculte de Chimie, U.S.T.H.B, 16111 El Alia, Alger, Algeria. a.badjah@arn.dz
authors.forename: Fairouz
authors.initials: F
authors.lastname: Tazerouti
authors.forename: Ahmed Yacine
authors.initials: AY
authors.lastname: Badjah-Hadj-Ahmed
authors.forename: Brahim Youcef
authors.initials: BY
authors.lastname: Meklati
authors.forename: Pilar
authors.initials: P
authors.lastname: Franco
authors.forename: Cristina
authors.initials: C
authors.lastname: Minguillon