title: Blood flow after intraarterial infusion chemotherapy in a patient with advanced cervical cancer.
abstract: We presented a case of locally advanced cervical cancer treated by intraarterial infusion chemotherapy, and evaluated the blood flow of uterine arteries before and after chemotherapy by using a transvaginal ultrasonic color Doppler device. Pulsatility index (PI) of each uterine artery increased after first course of chemotherapy compared to that of before chemotherapy. But PI did not change after second course in spite of a significant reduction in tumor size. Blood flow change assessed by Doppler ultrasound may be a limited but useful parameter for the efficacy of neoadjuvant chemotherapy in patients with cervical cancer.
authors.affiliation: Department of Obstetrics and Gynecology, Tottori Prefectural Central Hospital, Tottori, Japan. onohara@ruby.ocn.ne.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Minagawa
authors.forename: Y
authors.initials: Y
authors.lastname: Onohara
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Tsudo
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001158:Arteries; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007261:Infusions, Intra-Arterial; D008197:Lymph Node Excision; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D017663:Peplomycin / Q000008:administration & dosage; D011673:Pulsatile Flow; D018615:Ultrasonography, Doppler, Color; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000601:surgery; D014599:Uterus / Q000098:blood supply*
chemical_list: D016685:Mitomycin; D017663:Peplomycin; D002945:Cisplatin