Absorption of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides after oral application of Echinacea purpurea tincture.
Alkamides are suspected to contribute to the activity of Echinacea preparations. In preliminary experiments a quantification method for dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human blood has been developed by which it was possible to detect dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides in human blood after oral application of Echinacea purpurea mother tincture.
Dietz
B
B
Heilmann
J
J
Bauer
R
R
D000284:Administration, Oral; D000813:Anilides / Q000737:chemistry / Q000493:pharmacokinetics; D001682:Biological Availability; D020900:Echinacea; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000493:pharmacokinetics*; D006801:Humans; D010936:Plant Extracts / Q000737:chemistry / Q000493:pharmacokinetics; D018517:Plant Roots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D053284:Polyunsaturated Alkamides
C452804:2,4,8,10-dodecatetraenoic acid isobutylamide; D000813:Anilides; D005231:Fatty Acids, Unsaturated; D010936:Plant Extracts; D053284:Polyunsaturated Alkamides; C034595:benzanilide