title: [Descending necrotizing mediastinitis. Clinical experience and review of the literature].
abstract: The occurrence of a Descending Necrotizing Mediastinistis (DNM) usually is a consequence of oropharyngeal infections, which ultimately invade the mediastinum via the cervical fasciae. The clinical course is rapid and often fatal, and is associated with severe systemic symptoms, including fever and hypotension. In these cases, an aggressive surgical approach associated with an appropriate antibiotic treatment is mandatory. Personal experience in the treatment of DNM is presented and a review of the current literature is made; moreover an operative algorhythm is presented.
authors.affiliation: Istituto Polidisciplinare di Anestesia, Rianimazione e Terapia Antalgica, Trieste, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Pellis
authors.forename: G
authors.initials: G
authors.lastname: Berlot
authors.forename: V
authors.initials: V
authors.lastname: Giacomarra
authors.forename: M
authors.initials: M
authors.lastname: Bregant
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D013517:Otorhinolaryngologic Surgical Procedures
chemical_list: D000900:Anti-Bacterial Agents