The ICP-dependency of resistance to cerebrospinal fluid outflow: a new mathematical method for CSF-parameter calculation in a model with H-TX rats.
The international The simultaneous measurement of the resistance and compliance during a single investigation minimizes the patients exertion. In contrast to the classical method it is not necessary that the ICP reaches a plateau. Our mathematical method diverges with t he description of a pressure dependent slope of the function for the resistance from the static examination models. We proved our mathematical method by the use of a dynamic infusion test in 10 H-Tx rats without hydrocephalus and five hydrocephalic H-Tx rats. For that we are able to take the non linearity of the CSF resorption into consideration.
Meier
U
U
Department of Neurosurgery, Unfallkrankenhaus Berlin, Germany.
Kiefer
M
M
Bartels
P
P
D000818:Animals; D002555:Cerebrospinal Fluid / Q000502:physiology*; D003187:Compliance; D006849:Hydrocephalus / Q000503:physiopathology*; D007427:Intracranial Pressure; D008959:Models, Neurological; D011312:Pressure; D051381:Rats; D012016:Reference Values