title: Association between birthweight and body mass index at 3 years of age.
abstract: BACKGROUND
  Obesity in children is one of the risk factors for adulthood obesity, which then leads to the development of chronic diseases such as hypertension, hyperlipidemia and diabetes. In this study, we identified significant factors associating with the body mass index (BMI) at 3 years of age from the perinatal characteristics of children.
  
  
  METHODS
  A total of 588 children were included in the study. The BMI at 3 years of age was examined in conjunction with the possible variables such as parents' smoking status during pregnancy, parents' age at birth, gestational age, sibling number and live birth order, sex, birthweight, BMI at 1 month of age, weight gain during the first month of life and feeding method at 1 month of age.
  
  
  RESULTS
  Univariate analysis showed that birthweight (P<0.0001), weight gain during the first month of life (P=0.0012) and BMI at 1 month of age (P<0.0001) were significantly associated with the BMI at 3 years of age. Of these factors, birthweight and weight gain during the first month of life were the independent factors correlating with the BMI at 3 years by multivariate analysis (P<0.0001 and P=0.0095, respectively).
  
  
  CONCLUSIONS
  Infants with higher birthweight and/or greater weight gain during the first month of life may have a risk of being overweight at 3 years of age.
authors.affiliation: Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: A
authors.initials: A
authors.lastname: Matsuzaki
authors.forename: R
authors.initials: R
authors.lastname: Kuromaru
authors.forename: N
authors.initials: N
authors.lastname: Kinukawa
authors.forename: Y
authors.initials: Y
authors.lastname: Nose
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Hara
mesh_terms: D000367:Age Factors; D000704:Analysis of Variance; D001724:Birth Weight; D015992:Body Mass Index; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000254:growth & development*; D008297:Male; D009765:Obesity / Q000453:epidemiology; D012307:Risk Factors; D018709:Statistics, Nonparametric; D015430:Weight Gain / Q000502:physiology*