title: Group A streptococcal meningitis: report of a case and review of literature since 1976.
abstract: Group A streptococcal (GAS) invasive disease has become increasingly common in recent years. However, acute bacterial meningitis caused by this pathogen is unusual. We report a case of GAS meningitis in a previously healthy 21/2-year-old child associated with a dramatically rapid course and fatal outcome. A literature review of previously reported cases is presented. This case serves as a reminder that GAS can cause severe meningitis in otherwise healthy hosts.
authors.affiliation: Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA.
authors.forename: A K
authors.initials: AK
authors.lastname: Shetty
authors.forename: L R
authors.initials: LR
authors.lastname: Frankel
authors.forename: Y
authors.initials: Y
authors.lastname: Maldonado
authors.forename: D A
authors.initials: DA
authors.lastname: Falco
authors.forename: D B
authors.initials: DB
authors.lastname: Lewis
mesh_terms: D000293:Adolescent; D000328:Adult; D015984:Causality; D002443:Ceftriaxone / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016920:Meningitis, Bacterial / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D010406:Penicillins / Q000627:therapeutic use; D013297:Streptococcus pyogenes; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D010406:Penicillins; D014640:Vancomycin; D002443:Ceftriaxone