Prosthetic patch infection after carotid endarterectomy.
OBJECTIVE
prospective audit of the management and outcome of prosthetic patch infection after carotid endarterectomy (CEA) at Leicester Royal Infirmary plus review of the literature.


RESULTS
8/936 CEA patients (0.85%) developed a prosthetic patch infection. Responsible organisms included MRSA (n=3), Staphylococcus epidermidis(n=2), haemolytic Streptococcus (n=1), Staphylococcus aureus(n=1) and Pseudomonas (n=1). Early wound complications preceded 4/5 infections presenting within 9 weeks of surgery. In addition to systemic antibiotics and debridement, management included patch removal and: (i) carotid ligation (n=3), vein patch repair (n=1), vein bypass (n=3). One patient had antibiotic irrigation of the in-situpatch. No patient died, one suffered a disabling postoperative stroke and two had temporary cranial nerve injuries. Including this series, a literature review identified 43 prosthetic patch infections, 91% culturing Staphylococci or Streptococci. Cumulative freedom from perioperative stroke/death or re-infection was 65% at 2 years. Patients treated by patch excision and autologous venous reconstruction had the best outcome with a cumulative freedom from perioperative stroke/death or re-infection of 91% at 2 years.


CONCLUSIONS
prosthetic patch infection after CEA is rare. This study emphasises the importance of close surveillance of early wound complications. Surgical decision-making, especially the safety of carotid ligation, was facilitated by access to transcranial Doppler.
Naylor
A R
AR
Department of Vascular Surgery, Leicester Royal Infirmary, Leicester, UK.
Payne
D
D
London
N J M
NJ
Thompson
M M
MM
Dennis
M S
MS
Sayers
R D
RD
Bell
P R F
PR
D001424:Bacterial Infections / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D003428:Cross Infection; D016894:Endarterectomy, Carotid / Q000009:adverse effects*; D006801:Humans; D016343:Monitoring, Intraoperative; D011446:Prospective Studies; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000628:therapy; D011552:Pseudomonas Infections / Q000209:etiology / Q000628:therapy; D013203:Staphylococcal Infections / Q000628:therapy; D013290:Streptococcal Infections / Q000628:therapy; D013526:Surgical Mesh / Q000009:adverse effects*; D017585:Ultrasonography, Doppler, Transcranial