title: Evaluation of diagonal earlobe crease as a marker of coronary artery disease: the use of this sign in pre-operative assessment.
abstract: In this study, we examined the usefulness of the earlobe crease sign as a marker of coronary artery disease in the pre-operative assessment of patients. We were interested in evaluating this sign for use in emergency patients. We investigated 530 patients, aged > 40 years, undergoing elective surgery. If the electrocardiogram was abnormal or the patient reported symptoms suggesting coronary artery disease, further cardiac examinations were performed. Patients who demonstrated evidence of coronary artery disease in the additional investigations or had a clear history of coronary artery disease were classified as the abnormal coronary group. Other patients with no history and/or normal investigations were classified as the normal coronary group. The assessment of earlobe crease sign was performed prior to anaesthesia, and the sensitivity, specificity and positive predictive value of this sign were calculated. We found that the sensitivity and specificity was high regardless of age, except for specificity in patients > 70 years old. The data suggest that the earlobe crease sign may be a useful marker for the presence of coronary artery disease in patients undergoing emergency operations in which little or no history and investigations are available. However, more work is required to assess the use of this sign in other ethnic groups.
authors.affiliation: Department of Anaesthesiology, Osaka University Faculty of Medicine (D-7), 2-2, Yamada-oka, Suita Osaka, 565-0871, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kuri
authors.forename: Y
authors.initials: Y
authors.lastname: Hayashi
authors.forename: K
authors.initials: K
authors.lastname: Kagawa
authors.forename: K
authors.initials: K
authors.lastname: Takada
authors.forename: T
authors.initials: T
authors.lastname: Kamibayashi
authors.forename: T
authors.initials: T
authors.lastname: Mashimo
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D003327:Coronary Disease / Q000150:complications* / Q000175:diagnosis*; D004426:Ear Deformities, Acquired / Q000209:etiology*; D004431:Ear, External / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011300:Preoperative Care / Q000379:methods*; D012680:Sensitivity and Specificity