Mycobacterium avium intracellulare otitis media.
Atypical mycobacterial infections of the middle ear are extremely rare. To our knowledge, only eight cases have been reported in the literature, five of which involve Mycobacterium avium intracellulare. We present a case of culture-proven, M. avium intracellulare otomastoiditis in an 8-year-old boy with common variable immunodeficiency syndrome. The patient clinically presented with pain and otorrhea. The histopathology was marked by acid-fast bacilli-laden histiocytes. Consideration of this entity in the differential diagnosis of chronic, recalcitrant otorrhea can lead to timely diagnosis, treatment, an decreased morbidity.
Trupiano
J K
JK
Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Prayson
R A
RA
D002648:Child; D002908:Chronic Disease; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008417:Mastoiditis / Q000382:microbiology* / Q000473:pathology; D015269:Mycobacterium avium Complex / Q000302:isolation & purification* / Q000472:pathogenicity; D015270:Mycobacterium avium-intracellulare Infection / Q000150:complications* / Q000276:immunology / Q000473:pathology; D009894:Opportunistic Infections / Q000150:complications* / Q000276:immunology / Q000382:microbiology / Q000473:pathology