title: TMCompare: transmembrane region sequence and structure.
abstract: TMCompare is an alignment and visualization tool for comparison of sequence information for membrane proteins contained in SWISS-PROT entries, with structural information contained in PDB files. The program can be used for: detection of breaks in alpha helical structure of transmembrane regions; examination of differences in coverage between PDB and SWISS-PROT files; examination of annotation differences between PDB files and associated SWISS-PROT files; examination and comparison of assigned PDB alpha helix regions and assigned SWISS-PROT transmembrane regions in linear sequence (one letter code) format; examination of these differences in 3D using the CHIME plugin, allowing; analysis of the alpha and non-alpha content of transmembrane regions.
  
  
  BACKGROUND
  TMCompare is available for use through selection of a query protein via the internet (http://www.membraneproteins.org/TMCompare)
  
  
  BACKGROUND
  tmcompare@membraneproteins.org
authors.affiliation: Bioinformatics Laboratory, Embrapa-Genetic Resources and Biotechnology, Parque Estação Biológico Final Av. W/5 Norte CEP: 70770-900, Caixa Postal: 02372 Brasilia-DF, Brazil. tmcompare@membraneproteins.org
authors.forename: R C
authors.initials: RC
authors.lastname: Togawa
authors.forename: J F
authors.initials: JF
authors.lastname: Antoniw
authors.forename: J G
authors.initials: JG
authors.lastname: Mullins
mesh_terms: D001665:Binding Sites; D016208:Databases, Factual; D006801:Humans; D008565:Membrane Proteins / Q000032:analysis*; D011487:Protein Conformation; D016415:Sequence Alignment / Q000379:methods*; D012984:Software
chemical_list: D008565:Membrane Proteins