title: Branch retinal vein occlusion in a Japanese patient with neurofibromatosis 1.
abstract: BACKGROUND
  To report an Asian patient with branch retinal vein occlusion secondary to neurofibromatosis 1.
  
  
  METHODS
  A 64-year-old woman presented with a loss of vision in her right eye of 9-month duration. A diagnosis of neurofibromatosis 1 was made. A general medical examination showed no abnormalities except the signs of neurofibromatosis 1.
  
  
  METHODS
  Fundus examination of the right eye revealed irregularities of the venous caliber, partial sheathing of the corresponding vein and macular edema. Multiple dilated and tortuous collateral channels and an arteriovenous communication bridged the perfused and nonperfused retina. Fundus examination of the left eye showed a tortuous vein in the temporal region of the fovea. Fluorescein angiography of the right eye confirmed delayed filling in a superotemporal artery and in the corresponding vein. The temporal region of the fovea had large areas of capillary loss. The collaterals were tortuous and mimicked a neovascularization. Fluorescein angiography of the left eye confirmed that the vein in the temporal part of the fovea was tortuous and not leaking. A diagnosis of branch retinal vein occlusion of the superotemporal vein was made.
  
  
  CONCLUSIONS
  Neurofibromatosis 1 should be considered in the differential diagnosis of retinal vascular occlusive disease without other risk factors.
authors.affiliation: Department of Ophthalmology, Asahikawa Medical College, Asahikawa-shi, Hokkaido, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Mori
authors.forename: M
authors.initials: M
authors.lastname: Kawai
authors.forename: E
authors.initials: E
authors.lastname: Sato
authors.forename: S
authors.initials: S
authors.lastname: Igarishi
authors.forename: T
authors.initials: T
authors.lastname: Hikichi
authors.forename: A
authors.initials: A
authors.lastname: Yoshida
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000175:diagnosis / Q000208:ethnology; D012169:Retinal Vein / Q000473:pathology; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000208:ethnology / Q000209:etiology*; D014792:Visual Acuity