title: Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor.
abstract: The crystal structure of a cyclic form of a mutant of bovine pancreatic trypsin inhibitor has been solved at 1.0 A resolution. The protein was synthesized by native chemical ligation and its structure is almost indistinguishable from the previously described recombinant form of the same mutant; however, the new loop containing the former termini became much better ordered.
authors.affiliation: Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute at Frederick, MD 21702, USA.
authors.forename: I
authors.initials: I
authors.lastname: Botos
authors.forename: Z
authors.initials: Z
authors.lastname: Wu
authors.forename: W
authors.initials: W
authors.lastname: Lu
authors.forename: A
authors.initials: A
authors.lastname: Wlodawer
mesh_terms: D000818:Animals; D007611:Aprotinin / Q000737:chemistry*; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D004220:Disulfides; D008958:Models, Molecular; D009154:Mutation; D017510:Protein Folding; D017434:Protein Structure, Tertiary; D011994:Recombinant Proteins / Q000737:chemistry; D013997:Time Factors
chemical_list: D004220:Disulfides; D011994:Recombinant Proteins; D007611:Aprotinin