title: Time for total shift to first-trimester screening for Down's syndrome.
authors.affiliation: Reproductive Epidemiology, University of Leeds, LS2 9NZ, Leeds, UK. h.s.cuckle@leeds.ac.uk
authors.forename: H
authors.initials: H
authors.lastname: Cuckle
mesh_terms: D004314:Down Syndrome / Q000175:diagnosis*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis / Q000379:methods*; D000509:alpha-Fetoproteins / Q000302:isolation & purification
chemical_list: D000509:alpha-Fetoproteins