[A case of squamous cell carcinoma of the oral floor showing a complete response to oral administration of UFT].
A 73-year-old male with squamous cell carcinoma of the oral floor (T1N0M0), who had not consented to radical treatment was treated with UFT by oral administration alone. After commencement of the administration, tumor remission was observed at 2 weeks and disappeared clinically at 8 weeks. The total period of oral administration of UFT was twenty-three months, and the total dose was 186.5 g as tegafur. Major adverse effects were pigmentation of hands and liver dysfunction. He remains under observation, and there is no evidence of tumor recurrence.
Ikeda
H
H
Second Dept. of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry.
Kitamura
A
A
Uehara
M
M
Tobita
T
T
Ohba
S
S
Nonaka
M
M
Fujisawa
A
A
Inokuchi
T
T
D000284:Administration, Oral; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D004338:Drug Combinations; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000188:drug therapy*; D012074:Remission Induction; D005641:Tegafur / Q000627:therapeutic use*; D014498:Uracil / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D004338:Drug Combinations; C096910:UFT(R) drug; D005641:Tegafur; D014498:Uracil