Intraepithelial gamma delta T cells exposed by functional genomics.
Epithelial tissues house gammadelta T cells, which are important for the mucosal immune system and may be involved in controlling malignancies, infections and inflammation. Whole-genome gene-expression analysis provides a new way to study the signals required for the activation of gammadelta T cells, their mode of action and relationships among cells of the mucosal immune system.
Boismenu
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Department of Immunology, The Scripps Research Institute, North Torrey Pines Road, La Jolla, CA 92037, USA. havran@scripps.edu
Havran
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WL
D020869:Gene Expression Profiling; D006801:Humans; D018928:Immunity, Mucosal; D016131:Lymphocyte Subsets / Q000276:immunology*; D020411:Oligonucleotide Array Sequence Analysis; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology* / Q000502:physiology