[Inhibitors of the platelet's receptor GPIIb/IIIA. Progress in the treatment of acute myocardial ischemia and future trends].
The possible mechanisms inducing acute coronary obstruction starting from the atherosclerotic plaque are illustrated. The effects of the inhibitors of the platelet's receptor GPIIb/IIIa and the results of the main trials performed using these inhibitors are reported. Finally, the results obtained immediately before their employment in the coronary angioplasty with or without stent's implantation are also reported. The first applications in acute ischemic stroke appear to be favourable too.
Cacciapuoti
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Insegnamento delle Malattie Cardiovascolari, Cattedra di Medicina Interna, Scuola di Specializzazione in Diabetologia e Malattie del Ricambio, Seconda Università degli Studi, Naples, Italy.
D005544:Forecasting; D006801:Humans; D017202:Myocardial Ischemia / Q000188:drug therapy*; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*
D019039:Platelet Glycoprotein GPIIb-IIIa Complex