title: Primary arthroplasty of infected hips and knees in special cases using antibiotic-loaded bone-cement for fixation.
abstract: As a consequence of successful 1-stage exchange of infected joint prostheses, we decided to treat bacterial infection of the hip or knee by joint resection, synovectomy, and primary implantation of a hip or stabilized knee prosthesis. Since 1984, we have performed this procedure on 51 hips and 32 knees. All operations were preceded by identification of the causative organism and choice of appropriate antibiotics for addition to the bone-cement. The long-term rate of success corresponds to that of 1-stage exchange of infected prostheses. The different anatomic conditions at the hip and knee have to be taken into consideration. This treatment is restricted to special cases and should be performed only in specialized clinics with competent assistance from a bacteriologist.
authors.affiliation: Endo-Klinik, Hamburg, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Siegel
authors.forename: L
authors.initials: L
authors.lastname: Frommelt
authors.forename: W
authors.initials: W
authors.lastname: Runde
authors.forename: E
authors.initials: E
authors.lastname: Engelbrecht
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001843:Bone Cements; D016503:Drug Delivery Systems; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements