Efficient enantioselective hydrosilylation of ketones catalyzed by air stable copper fluoride-phosphine complexes.
[reaction: see text] Copper(II) fluoride-chiral diphosphine systems catalyze the hydrosilylation of several ketones with moderate to excellent enantioselectivities. An oxygen acceleration effect was observed and led to a practical protocol with low catalyst loading.
Sirol
S
S
Laboratoire de Chimie Organique et Médicinale, Place Louis Pasteur, 1, Université catholique de Louvain, B-1348 Louvain-La-Neuve, Belgium.
Courmarcel
J
J
Mostefai
N
N
Riant
O
O