title: Relationship of comorbidity, age and perioperative complications in patients undergoing radical prostatectomy.
abstract: OBJECTIVE
  To investigate the prevalence and distribution of comorbidity and its association with perioperative complications in patients undergoing radical prostatectomy (RPE).
  
  
  METHODS
  In 431 unselected RPE patients, the American Society of Anesthesiologists Physical Status classification (ASA-PS), the New York Heart Association classification of cardiac insufficiency (NYHA), the classification of angina pectoris of the Canadian Cardiovascular Society (CCS), height, weight, the body mass index (BMI), and the number of concomitant diseases (NCD) were assessed and related to perioperative cardiovascular complications.
  
  
  RESULTS
  In RPE patients less than 70 years old, comorbidity rose nearly continuously with increasing age. However, after reaching an age of 70 years, the proportion of NYHA-0 patients increased (60-64 years, 86%; 65-69 years, 85%; >or=70 years, 87%). Furthermore, the severe comorbidities decreased in patients selected for RPE aged 70 or more years. There was a nonsignificant trend towards higher comorbidity in patients with perioperative cardiovascular complications.
  
  
  CONCLUSIONS
  These data suggest that documentation of the distribution of ASA-PS, CCS, NYHA and of concomitant diseases might be helpful to characterize the general health status and the degree of selection of prostate cancer treatment populations especially in series with a high portion of patients aged 70 or more years. Concerning perioperative complications, the individual predictive value of comorbidity seems to be poor in the radical prostatectomy setting.
authors.affiliation: Department of Urology, University Clinics Carl Gustav Carus, Technical University of Dresden, Germany. Michael.Froehner@mailbox.tu-dresden.de
authors.forename: M
authors.initials: M
authors.lastname: Froehner
authors.forename: R
authors.initials: R
authors.lastname: Litz
authors.forename: A
authors.initials: A
authors.lastname: Manseck
authors.forename: O W
authors.initials: OW
authors.lastname: Hakenberg
authors.forename: S
authors.initials: S
authors.lastname: Leike
authors.forename: D M
authors.initials: DM
authors.lastname: Albrecht
authors.forename: M P
authors.initials: MP
authors.lastname: Wirth
mesh_terms: D000367:Age Factors; D000368:Aged; D000787:Angina Pectoris / Q000453:epidemiology*; D002318:Cardiovascular Diseases / Q000453:epidemiology; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D015995:Prevalence; D011468:Prostatectomy / Q000009:adverse effects*; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000601:surgery*; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology; D012189:Retrospective Studies; D013923:Thromboembolism / Q000453:epidemiology