title: Anaphylactoid reaction to etomidate: report of a case.
abstract: We report an anaphylactoid reaction to etomidate twice in a 60-year-old male with coronary artery disease and peripheral vascular disease. Following the first anaphylactoid reaction, the patient developed myocardial infarction. In addition, the patient's blood was moderately positive for latex antibodies, which made the differential diagnosis difficult. We concluded that the patient had anaphylactoid reaction to etomidate due to the temporal relationship to induction with the drug. The patient did not manifest similar reaction to other induction drugs used for other surgeries. The patient recovered from both incidents of anaphylactoid reaction to etomidate following intravenous administration of epinephrine and fluids.
authors.affiliation: Richard L. Roudebush Veterans Administration Medical Center, and Department of Anesthesia, Indiana University Medical Center, Indianapolis, IN 46202, USA. sreenivasa.moorthy@med.va.gov
authors.forename: S S
authors.initials: SS
authors.lastname: Moorthy
authors.forename: B
authors.initials: B
authors.lastname: Laurent
authors.forename: P
authors.initials: P
authors.lastname: Pandya
authors.forename: V
authors.initials: V
authors.lastname: Fry
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D018686:Anesthetics, Intravenous / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D005045:Etomidate / Q000009:adverse effects*; D006801:Humans; D007431:Intraoperative Complications; D020315:Latex Hypersensitivity / Q000150:complications / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology
chemical_list: D018686:Anesthetics, Intravenous; D005045:Etomidate