Peculiarities of myocardial structure in rats with hereditary hypertension reared by normotensive females.
Morphometric analysis revealed no signs of myocardial hypertrophy at the tissue and ultrastructural levels in 3-week-old NISAG rat pups reared by normotensive Wistar females. The severity of myocardial hypertrophy in these animals aging 6 months was similar to that in NISAG rats reared by natural mothers. However, raising conditions during the early ontogeny form compensatory structural changes in the myocardium of rats with genetically determined hypertension.
Korostyshevskaya
I M
IM
Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk. kor@iph.ma.nsc.ru
Maksimov
V F
VF
Markel'
A L
AL
Filyushina
E E
EE
Shmerling
M D
MD
Yakobson
G S
GS
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D006973:Hypertension; D009206:Myocardium / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors