Clinical implications of postsurgical adhesions.
Adhesion development can have a major impact on a patient's subsequent health. Adhesions are a significant source of impaired organ functioning, decreased fertility, bowel obstruction, difficult re-operation, and possibly pain. Consequently, their financial sequelae are also extraordinary, with more than one billion dollars spent in the USA in 1994 on the bowel obstruction component alone. Performing adhesiolysis for pain relief appears efficacious in certain subsets of women. Unfortunately even when lysed, adhesions have a great propensity to reform. Adhesions are prevalent in all surgical fields, and nearly any compartment of the body. For treatment of infertility and recurrent pregnancy loss, lysis of intrauterine adhesions results in improved fecundability and decreased pregnancy loss.
Diamond
M P
MP
Division of Reproductive Endocrinology and Infertility, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Freeman
M L
ML
D000328:Adult; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000473:pathology; D007421:Intestine, Small / Q000503:physiopathology; D008297:Male; D017699:Pelvic Pain / Q000191:economics / Q000473:pathology; D011183:Postoperative Complications; D011247:Pregnancy; D000267:Tissue Adhesions / Q000191:economics / Q000503:physiopathology / Q000628:therapy; D014591:Uterine Diseases / Q000209:etiology* / Q000503:physiopathology