Sputum isolation of Wangiella dermatitidis in patients with cystic fibrosis.
We report a case of invasive fungal pulmonary infection in a cystic fibrosis patient. Clinical deterioration coincided with isolation of Wangiella dermatitidis from her sputum, and treatment with amphotericin B followed by voriconazole resulted in clinical improvement and sterilization of the sputum. This case suggests that W. dermatitidis may be an etiologic agent of invasive pulmonary disease in the cystic fibrosis population.
Diemert
D
D
Department of Medicine, University of Alberta, Edmonton, Canada.
Kunimoto
D
D
Sand
C
C
Rennie
R
R
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003550:Cystic Fibrosis / Q000150:complications*; D005093:Exophiala / Q000302:isolation & purification*; D005260:Female; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D008172:Lung Diseases, Fungal / Q000188:drug therapy / Q000382:microbiology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D011743:Pyrimidines / Q000627:therapeutic use; D013183:Sputum / Q000382:microbiology; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D000666:Amphotericin B; D065819:Voriconazole