An immunosuppressive tryptophan-derived alkaloid from Lepidagathis cristata.
An immunosuppressive, tryptophan-derived alkaloid cristatin A (1), and two known compounds, cycloartenol and stigmasta-5,11(12)-diene-3 beta-ol, were isolated from the whole plant Lepidagathis cristata Willd. The structures of the isolates were established by interpretation of their spectral data.
Ravikanth
V
V
Indian Institute of Chemical Technology, Hyderabad, 500 007India.
Niranjan Reddy
V L
VL
Ramesh
P
P
Prabhakar Rao
T
T
Diwan
P V
PV
Khar
A
A
Venkateswarlu
Y
Y
D027901:Acanthaceae / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D007166:Immunosuppressive Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008214:Lymphocytes / Q000187:drug effects; D051379:Mice; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes; D014364:Tryptophan / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*
D000470:Alkaloids; D007166:Immunosuppressive Agents; D010840:Phytosterols; D014315:Triterpenes; C447012:cristatin A; D014364:Tryptophan; C100089:cycloartenol