title: Bone response to radio frequency sputtered calcium phosphate implants and titanium implants in vivo.
abstract: The objective of this study was to evaluate the effect of radio frequency sputtered calcium phosphate (CaP) coatings of titanium (Ti) implants on the bond strength at the bone-implant interface and percent bone contact length. Cylindrical coated or noncoated implants (4.0-mm diameter by 8-mm long) were implanted for 3 and 12 weeks. At 3 weeks after implant placement, the ultimate interfacial strengths for as-deposited CaP-coated and heat-treated CaP-coated implants were 2.29 +/- 0.14 MPa and 1.28 +/- 0.04 MPa, respectively. These ultimate interfacial strength values at 3 weeks were statistically greater than the mean ultimate interfacial strength for control Ti implants (0.67 +/- 0.13 MPa). At 12 weeks after implant placement, no statistical differences in the mean ultimate interfacial strengths were observed between the as-deposited CaP-coated, heat-treated CaP-coated, and control Ti implants. Histomorphometric evaluation indicated greater percent bone contact lengths for the as-deposited CaP-coated implants compared with the heat-treated CaP-coated and control Ti implants 3 and 12 weeks after implant placement.
authors.affiliation: Department of Restorative Dentistry, Division of Biomaterials, University of Texas Health Science Center at San Antonio, Texas 78284-7890, USA. ong@uthscsa.edu
authors.forename: J L
authors.initials: JL
authors.lastname: Ong
authors.forename: K
authors.initials: K
authors.lastname: Bessho
authors.forename: R
authors.initials: R
authors.lastname: Cavin
authors.forename: D L
authors.initials: DL
authors.lastname: Carnes
mesh_terms: D000818:Animals; D001846:Bone Development; D001842:Bone and Bones; D002130:Calcium Phosphates; D004285:Dogs; D008297:Male; D019736:Prostheses and Implants; D011846:Radio Waves; D014025:Titanium
chemical_list: D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; D014025:Titanium; C485829:calcium phosphate, dibasic, anhydrous