Tetra-trifluoroethoxyl zinc phthalocyanine: potential photosensitizer for use in the photodynamic therapy of cancer.
Tetra(trifluoroethoxyl) zinc phthalocyanine, which could be dissolved in most organic solvents, was synthesized. The compound displays a good photocytotoxicity on myeloma cells and Chinese hamster ovary cells in vitro in the presence of the emulsifying agent F68.
Gao
L
L
Institute of Pesticides and Pharmaceuticals, East China University of Science and Technology, Shanghai 200237, China.
Qian
X
X
Zhang
L
L
Zhang
Y
Y
D000818:Animals; D016466:CHO Cells; D002452:Cell Count; D002470:Cell Survival / Q000187:drug effects; D006224:Cricetinae; D007211:Indoles / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure; D009101:Multiple Myeloma; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000737:chemistry / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D007211:Indoles; D009942:Organometallic Compounds; D017319:Photosensitizing Agents