title: Periampullary tumors. Analysis of 319 consecutive cases submitted to preoperative endoscopic biliary drainage.
abstract: BACKGROUND
  During the last 2 decades, endoscopic retrograde cholangiopancreatography (ERCP) has been widely used for the diagnosis of periampullary tumors and the preoperative or definitive treatment of jaundice.
  
  
  METHODS
  We performed a retrospective analysis of 319 consecutive patients (184 men and 135 women with an average age of 66.5 years) who underwent ERCP for periampullary tumors between 1987 and 1999.
  
  
  RESULTS
  Endoscopic internal biliary drainage was successful in 293 patients (92%), with some differences due to the origin of the tumor. There were five complications (1.5%), including four bleeds and one retroduodenal perforation. There were no deaths related to the endoscopic drainage. Eighty-four patients underwent pancreaticoduodenectomy. The postoperative morbidity rate was 23%, and the overall mortality rate was 4.8%.
  
  
  CONCLUSIONS
  ERCP is a valid technique for the detailed preoperative assessment of periampullary tumors. It is also a safe method for internal biliary drainage.
authors.affiliation: Department of General Surgery, Catholic University School of Medicine, Largo A. Gemelli, 8-00168 Rome, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Coppola
authors.forename: M E
authors.initials: ME
authors.lastname: Riccioni
authors.forename: S
authors.initials: S
authors.lastname: Ciletti
authors.forename: L
authors.initials: L
authors.lastname: Cosentino
authors.forename: V
authors.initials: V
authors.lastname: Ripetti
authors.forename: P
authors.initials: P
authors.lastname: Magistrelli
authors.forename: A
authors.initials: A
authors.lastname: Picciocchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003138:Common Bile Duct Neoplasms / Q000601:surgery*; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D016896:Treatment Outcome