title: Pulmonary resection in metastatic uterine and cervical malignancies.
abstract: OBJECTIVE
  Although thoracotomy for removal of pulmonary metastasis is well documented in a wide variety of solid tumors, data are sparse regarding management of patients with gynecologic malignancies metastatic to the lung.
  
  
  METHODS
  We retrospectively reviewed the Roswell Park Cancer Institute experience between 1982 and 1999. Of 82 eligible patients with gynecologic tumors metastatic and confined to the lung, 25 underwent pulmonary resection.
  
  
  RESULTS
  There were 60 uterine and 22 cervix cancer patients with pulmonary metastases. Among patients with uterine cancer primaries undergoing pulmonary resection (n = 19) median survival was 26 months. Uterine cancer patients who underwent surgical resection for leiomyosarcomas (n = 11) had a median survival of 25 months compared to 46 months in patients with adenocarcinoma (n = 6, P = 0.02). Median survival in cervix cancer patients undergoing resection for pulmonary metastases (n = 6) was 36 months.
  
  
  CONCLUSIONS
  Pulmonary resection may provide a survival advantage for selected patients with uterine and cervical malignancies with metastases isolated to the lung.
authors.affiliation: Department of Surgical Oncology, Roswell Park Cancer Institute and SUNY at Buffalo, 14263, USA. Timothy.Anderson@RoswellPark.org
authors.forename: T M
authors.initials: TM
authors.lastname: Anderson
authors.forename: J J
authors.initials: JJ
authors.lastname: McMahon
authors.forename: C E
authors.initials: CE
authors.lastname: Nwogu
authors.forename: M W
authors.initials: MW
authors.lastname: Pombo
authors.forename: J D
authors.initials: JD
authors.lastname: Urschel
authors.forename: D L
authors.initials: DL
authors.lastname: Driscoll
authors.forename: S B
authors.initials: SB
authors.lastname: Lele
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000556:secondary / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery*; D008875:Middle Aged; D012189:Retrospective Studies; D013908:Thoracotomy; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*