title: A reversed phase high performance liquid chromatography method for the analysis of boswellic acids in Boswellia serrata.
abstract: An HPLC method for the separation of boswellic acids, the active constituents in Boswellia serrata resin has been developed. The first accurate determination of 6 individual acids was possible in the resin as well as in multi-component preparations. By using an acidic mobile phase, raised temperature and a 4 microm Synergi MAX-RP 80 A column the acids could be detected at levels as low as 0.9 microg/ml. The study of market products revealed significant variations in the content of these pharmacologically active compounds in commercial samples.
authors.affiliation: National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, Mississippi 38677, USA.
authors.forename: M
authors.initials: M
authors.lastname: Ganzera
authors.forename: I A
authors.initials: IA
authors.lastname: Khan
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry; D029743:Boswellia / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D008515:Medicine, Ayurvedic; D012116:Resins, Plant / Q000032:analysis / Q000737:chemistry; D014315:Triterpenes / Q000032:analysis* / Q000737:chemistry
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D012116:Resins, Plant; D014315:Triterpenes; C049844:salai guggal; C054625:boswellic acid