Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor.
The crystal structure of a cyclic form of a mutant of bovine pancreatic trypsin inhibitor has been solved at 1.0 A resolution. The protein was synthesized by native chemical ligation and its structure is almost indistinguishable from the previously described recombinant form of the same mutant; however, the new loop containing the former termini became much better ordered.
Botos
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I
Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute at Frederick, MD 21702, USA.
Wu
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Z
Lu
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Wlodawer
A
A
D000818:Animals; D007611:Aprotinin / Q000737:chemistry*; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D004220:Disulfides; D008958:Models, Molecular; D009154:Mutation; D017510:Protein Folding; D017434:Protein Structure, Tertiary; D011994:Recombinant Proteins / Q000737:chemistry; D013997:Time Factors
D004220:Disulfides; D011994:Recombinant Proteins; D007611:Aprotinin