Anomalies of the inferior vena cava in patients with iliac venous thrombosis.
BACKGROUND
Cases of deep venous thrombosis in the lower extremities triggered by abnormalities of the vena cava have been reported.


OBJECTIVE
To describe anomalies of the inferior vena cava in patients with deep venous thrombosis.


METHODS
Prospective, consecutive case series.


METHODS
University Hospital, Graz, Austria.


METHODS
97 patients with deep venous thrombosis.


METHODS
Sonography, venography, or both to diagnose deep venous thrombosis; magnetic resonance angiography to image the inferior vena cava.


METHODS
Anomalies of the inferior vena cava imaged by magnetic resonance angiography.


RESULTS
31 of 97 patients showed thrombotic occlusion of iliac veins (common and external iliac vein [ n = 29] or external iliac vein [ n = 2]). Five of 31 patients (3 men, 2 women) had an anomaly of the inferior vena cava. Anomalies were missing inferior vena cava, hypoplastic hepatic segment, and missing renal or postrenal segments. Patients with anomalies were significantly younger than the 92 patients without (mean age+/-SD, 25+/-6 years vs. 53+/-19 years; P = 0.002). In 2 patients with anomalies, the thrombotic occlusion was recurrent.


CONCLUSIONS
An anomaly of the inferior vena cava should be suspected if thrombosis involving the iliac veins is seen in patients 30 years of age or younger. Patients with both an anomaly and thrombosis may be at higher risk for thrombotic recurrence.
Obernosterer
Andrea
A
Division of Angiology, Department of Internal Medicine, Karl-Franzens University, Auenbruggerplatz 15, 8036 Graz, Austria. andrea.obernosterer@kfunigraz.ac.at
Aschauer
Manuela
M
Schnedl
Wolfgang
W
Lipp
Rainer W
RW
D000328:Adult; D000368:Aged; D006801:Humans; D007084:Iliac Vein / Q000000981:diagnostic imaging; D018810:Magnetic Resonance Angiography; D008875:Middle Aged; D011446:Prospective Studies; D012008:Recurrence; D012307:Risk Factors; D014463:Ultrasonography; D014682:Vena Cava, Inferior / Q000002:abnormalities* / Q000000981:diagnostic imaging; D020246:Venous Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging