Creutzfeldt-Jakob disease and blood transfusions: a meta-analysis of case-control studies.
A meta-analysis of five published case-control studies that examined the association between previous blood transfusions and Creutzfeld-Jakob disease was performed. The results demonstrated that controls were more likely (p < 0.001, odds ratio = 1.56, 95% confidence interval, 1.22-1.98) to have received previous blood transfusions (18.7%) than Creutzfeld-Jakob disease patients (12.9%), suggesting that selection bias of the control populations had occurred.
Riggs
J E
JE
Department of Neurology, West Virginia University School of Medicine, Morgantown, WV 26506-9180, USA.
Moudgil
S S
SS
Hobbs
G R
GR
D016022:Case-Control Studies; D016009:Chi-Square Distribution; D016001:Confidence Intervals; D007562:Creutzfeldt-Jakob Syndrome / Q000635:transmission*; D006801:Humans; D016017:Odds Ratio; D015983:Selection Bias; D065227:Transfusion Reaction