[127 cases of pulmonary fungal infection].
OBJECTIVE
To find out the clinical features, therapeutic outcome, prognosis and the major predisposing diseases of pulmonary fungal infection(PFI).


METHODS
127 cases with PFI were retrospectively analyzed.


RESULTS
Various predisposing diseases were found in 95% of total cases, among them, COPD, systemic lupus erythromatus(SLE), leukemia and chronic renal disease were main predisposing diseases. Primary pulmonary fungal infection was rare. All the clinical manifestations of PFI were not specific, reontgenographic features showed mainly bronchitis type(61%). Monilia (Candida) was ranked the first pathogen (79.5%). The mortality of PIF was high. Chronic renal and hematological diseases might be the risk factors for mortality (RR, relative rate, 5.14).


CONCLUSIONS
PFI is an important cause of the secondary infection in many diseases. The clinical features of PFI is non-specific and the morbidity is rising. Clinicians should pay more attention to it.
Qian
X
X
Department of Respiratory Disease, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhu
Y
Y
Xu
W
W
D001991:Bronchitis / Q000150:complications / Q000382:microbiology; D002175:Candida / Q000302:isolation & purification; D002177:Candidiasis / Q000150:complications / Q000382:microbiology* / Q000401:mortality; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D007938:Leukemia / Q000150:complications; D008168:Lung / Q000382:microbiology / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000150:complications / Q000382:microbiology* / Q000401:mortality; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications; D015996:Survival Rate