title: Computer-assisted ECG interpretation for confirmation of premature atrial complexes.
abstract: Current programs for computerized ECG analysis are not interactive. We developed custom software for computer-assisted ECG interpretation that functioned interactively with an observer directing the computerized process. The software was first used for recognition of PACs superimposed on ST-T waveforms. The interactive process included 6 steps. 1) The computer displayed the 12-lead ECG and the user selected the most frequent QRS-T waveforms for averaging. 2) The computer generated and displayed the averaged QRS-T waveform. 3) The user selected waveforms suspected to have PACs superimposed on the ST-T segments. 4) The computer generated and displayed the difference waveform by subtracting the average waveform from the suspect waveforms. 5) The user recognized and p-waves in the difference waveform and marked the onset and offset by positioning the cursor and clicking. 6) The computer then measured p-wave amplitudes, durations, and areas and displayed the recognized p-wave. The program was developed using digital data from 2 ECGs and tested on 39 ECGs with suspected PACs and 26 control ECGs.
  
  
  RESULTS
  The software and user interaction recognized 79 PACs in the suspect group. Control ECGs were analyzed using 3 complexes with the same leads and onsets as the test group. Of the 79 PACs found in the suspect group, mean values included an area under the curve of 4.0 +/- 3.2 microV-s for the test group versus 0.4 +/- 0.4 microV-s for the control (P < 0.001) and peak-to-trough voltage amplitudes of 104 +/- 66 microV versus 15 +/- 7 microV for the control (P < 0.001). The average time of onset of the premature complexes was 282 +/- 120 msec, and their duration was 100 +/- 28 msec.
  
  
  CONCLUSIONS
  Custom software combined the superior human pattern recognition with the digital signal processing of the computer. This enhanced recognition of ectopic atrial activity.
authors.affiliation: Department of Medicine, Section of Cardiology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
authors.forename: C W
authors.initials: CW
authors.lastname: Musser
authors.forename: T W
authors.initials: TW
authors.lastname: Simmons
authors.forename: W K
authors.initials: WK
authors.lastname: Haisty
mesh_terms: D018880:Atrial Premature Complexes / Q000175:diagnosis*; D004562:Electrocardiography; D006801:Humans; D012815:Signal Processing, Computer-Assisted; D012984:Software