title: Alpha1-antitrypsin deficiency--a model for conformational diseases.
authors.affiliation: Department of Hematology, University of Cambridge, Cambridge Institute for Medical Research, Cambridge, United Kingdom. rwc1000@cam.ac.uk
authors.forename: Robin W
authors.initials: RW
authors.lastname: Carrell
authors.forename: David A
authors.initials: DA
authors.lastname: Lomas
mesh_terms: D003704:Dementia / Q000209:etiology / Q000628:therapy; D004646:Emphysema / Q000209:etiology; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology; D008954:Models, Biological; D009154:Mutation; D019636:Neurodegenerative Diseases / Q000209:etiology / Q000628:therapy; D011480:Protease Inhibitors / Q000378:metabolism*; D011487:Protein Conformation; D015843:Serpins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D000515:alpha 1-Antitrypsin / Q000737:chemistry; D019896:alpha 1-Antitrypsin Deficiency / Q000378:metabolism*
chemical_list: D011480:Protease Inhibitors; D015843:Serpins; D000515:alpha 1-Antitrypsin; D010450:Endopeptidases