Myoclonus secondary to withdrawal from transdermal fentanyl: case report and literature review.
Myoclonus is a common and well-described adverse effect of opioids. Most cases reported in the literature have been associated with opioid administration, rather than with opioid withdrawal. We describe a case of myoclonus secondary to withdrawal from transdermal fentanyl. We review the literature regarding myoclonus related to opioid therapy (opioid-induced myoclonus) and withdrawal (opioid withdrawal myoclonus), and discuss possible mechanisms and therapies for these phenomena.
Han
Paul K J
PK
Section of Palliative Care and Medical Ethics Division of General Internal Medicine, University of Pittsburgh Medical Center, 5320 Centre Avenue, Pittsburgh, PA 15232, USA.
Arnold
Robert
R
Bond
Geoffrey
G
Janson
Douglas
D
Abu-Elmagd
Kareem
K
D000279:Administration, Cutaneous; D000328:Adult; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D009207:Myoclonus / Q000139:chemically induced*; D013375:Substance Withdrawal Syndrome
D005283:Fentanyl