[Clinical study on effect of Chinese herbal medicine on liver damage caused by hepatic artery chemoembolization].
OBJECTIVE
To observe the effect of Chinese herbal medicine on hepatic artery chemoembolization caused liver damage.


METHODS
One hundred and ten patients, who received hepatic artery chemoembolization, were divided into two groups, 60 patients in the treated group were treated with Qinggan Jiedu Sanjie Decoction and the other 50 Patients in the control group treated with routine western medicine. The changes of liver function, cirrhosis incidence and exacerbation rate of both groups were observed.


RESULTS
The total liver function deterioration rate of the treated group, according to Child's grading standard, was 46.67%, while that of the control group was 68.00%, the former was much lower than the latter (P < 0.05). The cirrhosis incidence and exacerbation rate in the treated group were 35.00% (7/20) and 50.00% (20/40) respectively, while in the control group, they were 65.00% (13/20) and 76.67% (23/30) respectively. The difference between the two groups was also significant (P < 0.05).


CONCLUSIONS
Qinggan Jiedu Sanjie Decoction has some effect on alleviating and preventing hepatic damage caused by hepatic artery chemoembolization.
Liu
C
C
Zhaoqing Municipal Hospital of TCM, Guangdong (526020).
Cai
Y
Y
Huang
Z
Z
D000328:Adult; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D008107:Liver Diseases / Q000209:etiology / Q000517:prevention & control*; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage
D016685:Mitomycin; D004317:Doxorubicin; D002945:Cisplatin