Nasal administration of Schistosoma mansoni egg antigens-cholera toxin B subunit conjugate to infected mice reduces immunopathology and mortality.
Sun
J B
JB
Department of Medical Microbiology and Immunology, Göteborg University, Sweden.
Li
B L
BL
Lakew
M
M
Grzych
J M
JM
Capron
A
A
Czerkinsky
C
C
Holmgren
J
J
D000281:Administration, Intranasal; D000818:Animals; D000947:Antigens, Helminth / Q000008:administration & dosage*; D002772:Cholera Toxin / Q000008:administration & dosage*; D005260:Female; D006099:Granuloma / Q000473:pathology / Q000517:prevention & control; D000922:Immunotoxins / Q000008:administration & dosage*; D007376:Interleukin-2 / Q000096:biosynthesis; D007377:Interleukin-3 / Q000096:biosynthesis; D015847:Interleukin-4 / Q000096:biosynthesis; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology; D008107:Liver Diseases / Q000473:pathology / Q000517:prevention & control; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D008807:Mice, Inbred BALB C; D010063:Ovum / Q000276:immunology; D012550:Schistosoma mansoni / Q000276:immunology*; D012555:Schistosomiasis mansoni / Q000276:immunology / Q000473:pathology / Q000628:therapy*
D000947:Antigens, Helminth; D000922:Immunotoxins; D007376:Interleukin-2; D007377:Interleukin-3; D015847:Interleukin-4; D002772:Cholera Toxin