[Analysis of pregnancy rates after treatment of tubal pregnancy with systemic methotrexate].
OBJECTIVE
To analyse the pregnancy rate after treatment of tubal pregnancy with the systemic methotrexate (MTX) injection.


METHODS
From March 1985 to August 1999, 129 women with confirmed unruptured tubal pregnancy, and desiring to conceive were selected. Among them 60 women were successfully treated with systemic MTX, and 69 with unilateral salpingectomy. All cases were followed up for 1-15 years.


RESULTS
The rates of subsequent intrauterine pregnancies (IUP) in the MTX group was 73% (44 cases) and of recurrent extrauterine pregnancies (EP) was 8% (5 cases). Among 69 patients treated by salpingectomy, the rates of IUP and EP was 70% (48 cases) and 4% (3 cases) respectively. The differences between the two groups were not statistically significant.


CONCLUSIONS
The effect of conservative management with MTX was similar to those of salpingectomy. The rate of subsequent pregnancy did not increased.
Li
M
M
Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing 100029, China.
Bian
M
M
Wang
J
J
D000328:Adult; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D018873:Pregnancy Rate; D011274:Pregnancy, Tubal / Q000188:drug therapy* / Q000601:surgery
D008727:Methotrexate