title: [Molar pregnancy. Retrospective study of 60 cases in Tunisia].
abstract: To identify the epidemiologic, clinical end therapeutic particularities of molar pregnancies in Tunisia. A retrospective study of 60 cases of molar pregnancy Diagnosis of MP was base on elevated urine HCG level and/or histologic examination of uterine revision done for all patients. The incidence of MP is 1/793(60/47624) pregnancies. The mean age of patients was 31.7 years and 16 patients had more than 35 years. The metrorragia is the main symptom (91.6%). Excessive uterine enlargement and lutein ovarian cysts were observed respectively in 57 and 6.6% of cases. Human chorionic gonadotropin level was upper than 50,000 UI/l in 91.4% of cases. Ultrasonography contributed to diagnosis in 82.8% of cases. Histological findings were complete molar in 33 cases and partial molar in 27 cases. 6 of 33 patients having complete molar developed persistent gestational trophoblastic tumor. Actinomycin D induced complete remission in all cases. Molar pregnancy is a relatively common disease in Tunisia. Careful and reliable human chorionic gonadotropin monitoring is essential for the early detection of post molar persistent gestational trophoblastic tumor.
authors.affiliation: Service de gynécologie obstétrique A Hôpital Charles Nicolle, Tunis.
authors.forename: A
authors.initials: A
authors.lastname: Chechia
authors.forename: A
authors.initials: A
authors.lastname: Koubâa
authors.forename: T
authors.initials: T
authors.lastname: Makhlouf
authors.forename: B
authors.initials: B
authors.lastname: Anis
authors.forename: K
authors.initials: K
authors.lastname: Terras
authors.forename: B
authors.initials: B
authors.lastname: Hamouda
authors.forename: F
authors.initials: F
authors.lastname: Mezni
mesh_terms: D000328:Adult; D017668:Age of Onset; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D003609:Dactinomycin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D016021:Epidemiologic Studies; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D015994:Incidence; D011247:Pregnancy; D011379:Prognosis; D012189:Retrospective Studies; D014416:Tunisia / Q000453:epidemiology; D016216:Ultrasonography, Prenatal; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D000903:Antibiotics, Antineoplastic; D003609:Dactinomycin
vernacular_title: Les grossesses môlaires. Etude rétrospective de 60 cas en Tunisie.