title: [Analysis of genetico-demographic structure of rural populations living near the Semipalatinsk nuclear test site].
abstract: Rural populations neighboring the Semipalatinsk nuclear test site were used as a model to develop and test an integrated population-genetic approach to analysis of the medical genetic situation and environmental conditions in the areas studied. The contributions of individual factors of population dynamics into the formation of the genetic load were also assessed. The informative values of some genetic markers were estimated. Based on these estimates, a mathematical model was constructed that makes it possible to calculate numerical scores for analysis of the genetic loads in populations differing in environmental exposure.
authors.affiliation: Republican Research Center for Maternal and Children's Health Protection, Almaty, 480020 Kazakhstan.
authors.forename: G S
authors.initials: GS
authors.lastname: Sviatova
authors.forename: G M
authors.initials: GM
authors.lastname: Berezina
authors.forename: G Zh
authors.initials: GZh
authors.lastname: Abil'dinova
mesh_terms: D003710:Demography; D004781:Environmental Exposure; D005828:Genetics, Population; D007623:Kazakhstan; D008962:Models, Theoretical; D009689:Nuclear Warfare; D011848:Radioactive Pollutants; D012424:Rural Population
chemical_list: D011848:Radioactive Pollutants
vernacular_title: Analiz genetiko-demograficheskoĭ struktury sel'skikh populiatsiĭ, prilegaiushchikh k semipalatinskomu ispytatel'nomu poligonu.