title: An advanced toothbrush with improved plaque removal efficacy.
abstract: OBJECTIVE
  To compare the plaque removal efficacy and safety of a new advanced manual toothbrush, the Oral-B CrossAction, with seven other toothbrushes.
  
  
  METHODS
  Seven independent, cross-over design clinical studies were conducted using the same examiner who was blind to the identity of the test products and treatment assignments. In each study, approximately 75 healthy adult subjects from a general population brushed with their randomly assigned toothbrush (CrossAction or comparison brush) at Visit 1 for 1 min without supervision or instruction in brushing technique. Subjects returned after a 1-week washout period and brushed with the alternate toothbrush (Visit 2). Plaque was evaluated before and after brushing using the Rustogi Modified Navy Plaque Index. Statistical analyses were conducted by an independent statistician who remained blind to the identity of all test products.
  
  
  RESULTS
  Each of the toothbrushes tested provided significant (P < or = 0.0001) reductions in plaque scores after a single brushing. In each of the studies, the CrossAction toothbrush removed significantly (P < or = 0.0001) greater amounts of whole mouth, gingival margin, and approximal plaque than the compared toothbrush. All toothbrushes were found to be safe, with no changes in oral tissues or restorations observed over the course of each study. The results from these studies were consistent, demonstrating that the CrossAction toothbrush significantly enhances the ability of subjects to remove more plaque during normal brushing compared to seven other toothbrushes.
authors.affiliation: BioSci Research Canada Ltd., Mississauga, Ontario.
authors.forename: N C
authors.initials: NC
authors.lastname: Sharma
authors.forename: J G
authors.initials: JG
authors.lastname: Qaqish
authors.forename: H J
authors.initials: HJ
authors.lastname: Galustians
authors.forename: D W
authors.initials: DW
authors.lastname: King
authors.forename: M A
authors.initials: MA
authors.lastname: Low
authors.forename: D M
authors.initials: DM
authors.lastname: Jacobs
authors.forename: D A
authors.initials: DA
authors.lastname: Weber
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D018592:Cross-Over Studies; D003773:Dental Plaque / Q000145:classification / Q000473:pathology / Q000628:therapy*; D003774:Dental Plaque Index; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D005881:Gingiva / Q000473:pathology; D006801:Humans; D008297:Male; D016037:Single-Blind Method; D014070:Tooth / Q000473:pathology; D014099:Toothbrushing / Q000295:instrumentation*; D016896:Treatment Outcome