Diagnosis and surgical treatment of posterior fossa solid hemangioblastomas.
OBJECTIVE
To elucidate the diagnosis and surgical treatment of the posterior fossa solid hemangioblastomas (PFSHs).


METHODS
The data from 22 patients with PFSHs verified by surgery and pathology were analyzed retrospectively and a review of relevant literature was conducted.


RESULTS
The preoperative definitive diagnosis rate was 13/22. Total tumor removal was achieved in 20 patients. Two of the 22 patients died after surgery, one of brain-stem injury and the other from an intracranial hemorrhage. Twenty patients were followed up for 2 months to 8 years (average, 2 years). Kamofsky scale was > or = 80 in 15 patients, 60-70 in 1 patient and not measured in 4 patients who died during follow-up. The causes of death were pneumonia (2 patients) and purulent meningitis (2).


CONCLUSIONS
MRI and DSA (digital subtraction angiography) are major preoperative diagnostic modalities for PFSH, but PFSH remains a challenging benign neoplasm. Special microsurgical techniques and improved operative manipulation can improve surgical efficacy.
Zhou
L
L
Department of Neurosurgery, Huashan Hospital, Shanghai Medical University, Shanghai 200040, China. lfzhou@shmu.edu.cn
Du
G
G
D000328:Adult; D000368:Aged; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D003388:Cranial Fossa, Posterior; D018325:Hemangioblastoma / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D012196:Review Literature as Topic; D015996:Survival Rate; D016896:Treatment Outcome