[Effects of xiaopi yishen oral liquid on hypothalamus-pituitary-adrenal gland-thymus axis in stressed rats].
OBJECTIVE
To investigate the effect of Xiaopi Yishen (XPYS) oral liquid on the rats under repeated forced cold water swimming (RFCWS) stress.


METHODS
The changes of serum monoamine, ascorbic acid levels in adrenal gland, monoamine levels in hypothalamus and hypophysis, and thymus index were determined.


RESULTS
XPYS lowered the increasing of serum DA, 5-HT, improved the reducing of ascorbic acid in adrenal gland and NE, HVA, 5-HT, 5-HITT in hypothalamus and hypophysis of RFCWS-stressed rats.


CONCLUSIONS
The mechanism of XPYS is in connection with the regulation of hypothalamus-pituitary-adrenal gland-thymus axis.
Wang
L
L
Beijing University of Traditional Chinese Medicine, Beijing (100029).
Wang
T
T
Kang
C
C
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000503:physiopathology*; D008297:Male; D010913:Pituitary-Adrenal System / Q000187:drug effects / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000503:physiopathology*; D013950:Thymus Gland / Q000187:drug effects / Q000503:physiopathology*
D004365:Drugs, Chinese Herbal