[Bicarbonate versus acetate hemodialysis: effects on the acid-base status].
BACKGROUND
Metabolic acidosis is an inevitable complication of chronic renal failure and one the major goals of haemodialysis (HD) treatment is correction of acidosis. The main aim of study was to compare effects of bicarbonate versus (vs) acetate HD on acid-base.


METHODS
A sample of 36 patients (pts) was done, 20 males and 16 females, aged 52.4 +/- 12.7 years, duration on HD 46.8 +/- 40.2 months, 15 pts on acetate and 21 pts on bicarbonate HD. We determined the parameters of acid-base before and after HD, electrolyte status, Kt/V and URR.


RESULTS
At start of HD: pH-7.33 +/- 0.04; pCO2-4.95 +/- 0.5 kPa; HCO3 19.1 +/- 1.9 mmol/L on bicarbonate HD vs. pH-7.33 +/- 0.03; pCO2-4.81 +/- 0.4kPa; HCO3(-)-18.7 +/- 2.0 mmol/L on acetate HD. At the end of session: pH-7.45 +/- 0.02; pCO2-5.07 +/- 0.4 kPa; HCO3(-)-26.3 +/- 1.5 mmol/L on bicarbonate HD vs. pH-7.43 +/- 0.03; pCO2-4.55 +/- 0.3 kPa; HCO3(-)-22.6 +/- 1.8 mmol/L on acetate HD.


CONCLUSIONS
Bicarbonate as a physiological buffer is much efficient in correction of metabolic acidosis and should be preferred in HD treatment.
Avdic
E
E
Institut za nefrologiju, KCU Sarajevo.
Suljevic
E
E
Helac-Cvijetic
D
D
D000085:Acetates; D000136:Acid-Base Equilibrium; D001639:Bicarbonates; D005260:Female; D015312:Hemodialysis Solutions; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods
D000085:Acetates; D001639:Bicarbonates; D015312:Hemodialysis Solutions
Bikarbonatna naspram acetatne hemodijalize: ucinci na acido-bazni status.