title: Hemoglobin adducts in rats chronically exposed to room-aged cigarette sidestream smoke and diesel engine exhaust.
abstract: Under controlled conditions with exaggerated concentrations of environmental aerosols, the biologically effective dose markers suggested in the literature as being specific for ETS (i.e., HPB Hb adducts for TSNA exposure) and DEE (i.e., l-aminopyrene Hb adducts for l-nitropyrene exposure) did not respond. A slight but dose-dependent increase in 4-ABP Hb adduct levels was seen in RASS-exposed rats.
authors.affiliation: INBIFO Institut für biologische Forschung, Cologne, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Stabbert
authors.forename: G
authors.initials: G
authors.lastname: Schepers
authors.forename: W S
authors.initials: WS
authors.lastname: Stinn
authors.forename: H J
authors.initials: HJ
authors.lastname: Haussmann
mesh_terms: D000818:Animals; D001336:Automobiles; D005260:Female; D005742:Gasoline / Q000009:adverse effects*; D006454:Hemoglobins / Q000378:metabolism*; D008297:Male; D011489:Protein Denaturation; D051381:Rats; D017208:Rats, Wistar; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*; D001335:Vehicle Emissions
chemical_list: D005742:Gasoline; D006454:Hemoglobins; D014028:Tobacco Smoke Pollution; D001335:Vehicle Emissions