title: A contact model with ingrowth control for bone remodelling around cementless stems.
abstract: This work presents a computational model for bone remodelling around cementless stems. The problem is formulated as a material optimisation problem considering the bone and stem surfaces to be in contact. To emphasise the behaviour of the bone/stem interface, the computer model detects the existence of bone ingrowth during the remodelling; consequently, the contact conditions are changed for a better interface simulation. The trabecular bone is modelled as a strictly orthotropic material with equivalent properties computed by homogenisation. The distribution of bone relative density is obtained by the minimisation of a function that considers both the bone structural stiffness and the biological cost associated with metabolic maintenance of bone tissue. The situation of multiple load conditions is considered. The remodelling law, obtained from the necessary conditions for an optimum, is derived analytically from the optimisation problem and solved numerically using a suitable finite element mesh. The formulation is applied to an implanted femur. Results of bone density and ingrowth distribution are obtained for different coating conditions. Bone ingrowth does not occur over the entire coated surfaces. Indeed, we observed regions where separation or high relative displacement occurs that preclude bone ingrowth attachment. This prediction of the model is consistent with clinical observations of bone ingrowth. Thus, this model, which detect bone ingrowth and allow modification of the interface conditions, are useful for analysis of existing stems as well as design optimisation of coating extent and location on such stems.
authors.affiliation: IDMEC-Instituto Superior Técnico, Liasboa, Portugal. prfernan@dem.ist.utl.pt
authors.forename: P R
authors.initials: PR
authors.lastname: Fernandes
authors.forename: J
authors.initials: J
authors.lastname: Folgado
authors.forename: C
authors.initials: C
authors.lastname: Jacobs
authors.forename: V
authors.initials: V
authors.lastname: Pellegrini
mesh_terms: D000818:Animals; D015519:Bone Density; D016723:Bone Remodeling / Q000502:physiology*; D020099:Coated Materials, Biocompatible; D005269:Femur / Q000503:physiopathology*; D020342:Finite Element Analysis; D006622:Hip Prosthesis; D006801:Humans; D008954:Models, Biological; D016348:Osseointegration
chemical_list: D020099:Coated Materials, Biocompatible