title: Treatment of postparotidectomy salivary fistula with botulinum toxin.
abstract: We report on the successful treatment with botulinum toxin type A local injections of a salivary fistula that occurred after superficial parotidectomy. In a 58-year-old woman, transcutaneous discharge of saliva in the preauricular region had persisted in spite of 2 surgical revisions. Moreover, facial weakness and synkinesis had developed as a result of an iatrogenic lesion that had occurred at the time of primary surgery and required immediate reanastomosis of the main nerve trunk. Botulinum toxin A was injected into the deep lobe of the remaining parotid gland under ultrasonographic guidance. Additionally, botulinum toxin A was injected into the left orbicularis oculi muscle in order to improve the synkinesis. No adverse effects were observed. The sialorrhea was stopped for 11 months, and the synkinesis of the facial muscles was reduced significantly for 4 months. We conclude that botulinum toxin A injection is a successful alternative for the treatment of chronic salivary fistula.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, University of Cologne, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Guntinas-Lichius
authors.forename: C
authors.initials: C
authors.lastname: Sittel
mesh_terms: D000235:Adenolymphoma / Q000601:surgery*; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007267:Injections; D008875:Middle Aged; D010305:Parotid Diseases / Q000175:diagnosis / Q000188:drug therapy*; D010306:Parotid Gland / Q000187:drug effects; D010307:Parotid Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy*; D012008:Recurrence; D012086:Reoperation; D012467:Salivary Gland Fistula / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D019274:Botulinum Toxins, Type A