title: Leopard-spot pattern of yellowish subretinal deposits in central serous chorioretinopathy.
abstract: OBJECTIVE
  To describe clinical and angiographic features of patients with central serous chorioretinopathy (CSC) who had yellowish subretinal deposits forming a reticulated leopard-spot pattern during fluorescein angiography.
  
  
  METHODS
  We conducted case studies using the clinical and photographic records of 5 patients.
  
  
  RESULTS
  All 5 patients were older men between the ages of 68 and 81 years who had been treated with corticosteroids and had bilateral CSC. Nine eyes of the 5 patients developed yellowish deposits in a reticulated pattern in the macular region under the chronic detached neurosensory retina. The pattern of leopard-spot deposits was well demonstrated on the fluorescein angiogram, with hypofluorescence in most of the deposits and hyperfluorescence from atrophy of the retinal pigment epithelium. Later phases of the fluorescein angiographic study showed leaks from the retinal pigment epithelium. During the indocyanine green angiography evaluation of 4 patients, all had bilateral multifocal patches of hyperfluorescence in the midphase, findings typical of CSC.
  
  
  CONCLUSIONS
  Yellowish deposits forming a reticulated leopard-spot pattern may occur under the neurosensory retina and are associated with chronic neurosensory detachment caused by CSC. All patients were older men being treated with corticosteroids. This report described a newly recognized finding: the subretinal deposition of a yellowish material in a leopard-spot pattern in eyes with CSC.
authors.affiliation: Vitreous-Retina-Macula Consultants of New York, 519 E 72nd St, Suite 203, New York, NY 10021, USA. vrmny@aol.com
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iida
authors.forename: Richard F
authors.initials: RF
authors.lastname: Spaide
authors.forename: Anton
authors.initials: A
authors.lastname: Haas
authors.forename: Lawrence A
authors.initials: LA
authors.lastname: Yannuzzi
authors.forename: Lee M
authors.initials: LM
authors.lastname: Jampol
authors.forename: Robert L
authors.initials: RL
authors.lastname: Lesser
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015862:Choroid Diseases / Q000150:complications / Q000175:diagnosis*; D005122:Exudates and Transudates; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology; D012164:Retinal Diseases / Q000150:complications / Q000175:diagnosis*