[Clinicopathologic features and prognosis of lymphoepithelioma-like carcinoma of the lung].
OBJECTIVE
To analyze the clinicopathologic features and prognosis of lymphoepithelioma-like carcinoma (LELC) of the lung.


METHODS
26 cases of pulmonary LELC with available long-term follow-up information were compared with 84 cases of pulmonary non-LELC(33 cases of squamous cell carcinoma, 36 cases of adenocarcinoma, 6 cases of adeno-squamous carcinoma and 9 cases of large cell carcinoma) with available long-term follow-up information using Kaplan-Meier method and the generalized Wilcoxon test.


RESULTS
LELC of the lung had a better prognosis than non-LELC (P < 0.05). Further study showed that pulmonary LELC had a significantly better prognosis than adeno-squamous carcinoma and large cell carcinoma. However, there was no significant prognostic differences between pulmonary LELC and squamous cell carcinoma and adenocarcinoma. Tumor recurrence and necrosis (> or = 5% of tumor) were associated with poor prognosis.


CONCLUSIONS
Pulmonary LELC, which is a very rare and unique entity, has a better prognosis after therapy.
Han
A
A
Department of Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou 510089, China.
Xiong
M
M
Gu
Y
Y
Lin
S
S
Xiong
M
M
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011379:Prognosis