[The relationship between maternal infection with human parvovirus B19 and fetal death and congenital malformation].
OBJECTIVE
To study the relationship between matanal infection with human parvovirus B19 and fetal death and congenital malformation.


METHODS
B19-DNA was detected by Polymerase Chain Reaction (PCR) in blood samples from 335 pregnant women. The pregnant outcomes were followed.


RESULTS
In 335 pregnant women, 67 cases were B19-DNA positive and 268 cases were B19-DNA regative. There were four fetal deaths and one anencephalus in B19-DNA positive group. There was no fetal deaths or congenital malformation in B19-DNA negative group. The difference is significant (P < 0.05).


CONCLUSIONS
Maternal infection with human parvovirus B19 may contribute to fetal death and congenital malformation.
Li
B
B
Department of Obstetrics and Gynecology, Central Hospital of Xi'an City, 710003 China.
Qu
X
X
Wang
S
S
D000013:Congenital Abnormalities / Q000453:epidemiology*; D005260:Female; D005313:Fetal Death / Q000453:epidemiology*; D006801:Humans; D010322:Parvoviridae Infections / Q000150:complications / Q000453:epidemiology; D016732:Parvovirus B19, Human; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D011256:Pregnancy Outcome