[Protein secretion from drug-resistant bacteria--a suitable target for new antibiotics].
This paper reviewed the pathways of bacterial protein secretion and discussed the targets of pathogenic bacteria for antibiotics. Inhibition of protein secretion could lead to the growth decline, morphological alteration, and reduction of bacterial virulence, as well as the deprivation of their drug resistant. It was concluded that protein secretion could be a suitable target for new antibiotic agents.
Guan
J
J
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041. guanjiafa@365.com
Fan
C
C
Liao
L
L
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism*; D015195:Drug Design; D024881:Drug Resistance, Bacterial / Q000502:physiology*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins