title: Paget's disease of the vulva: results of different conservative treatments.
abstract: OBJECTIVE
  To evaluate three conservative treatments for vulvar Paget's disease: wide excision, laser alone, or limited surgery associated with laser.
  
  
  METHODS
  A retrospective analysis of 52 patients treated with wide excision (31 cases), limited surgery, and peripheral laser [Br J Obstet Gynecol 1995;102:359], or laser alone [Gynecol Oncol 1975;3:46].
  
  
  RESULTS
  Mean time to recurrence was 1+/-0.6 years after laser alone, 1.9+/-1.5 years after the association limited excision and peripheral laser, and 2.7+/-1 years after wide excision alone. At 1 year recurrence rates were 67% after laser alone, 33% after the association laser plus surgery, and 23% after wide excision.
  
  
  CONCLUSIONS
  Conservative management preserves vulvar anatomy and function, but recurrence rates are high.
authors.affiliation: Department of Obstetrics and Gynecology, Maternité Centre Hospitalier Intercommunal, Intercommunal Hospital of Creteil, 40 Avenue de Verdun, 94010 Cedex, Creteil, France.
authors.forename: C
authors.initials: C
authors.lastname: Louis-Sylvestre
authors.forename: B
authors.initials: B
authors.lastname: Haddad
authors.forename: B J
authors.initials: BJ
authors.lastname: Paniel
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D010145:Paget Disease, Extramammary / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000601:surgery*