[Clinical and experimental study on the treatment of endometriosis with dan'e mixture].
OBJECTIVE
To find a medicine to treat endometriosis effectively with less side-effect.


METHODS
Dan'e mixture (DEM, consists of Radix Salviae Miltiorrhizae and Rhizoma Zedoariae) was used to treat 189 cases of endometriosis and the change of symptom and sign, the B ultrasonograph, the anti-endometrium antibody and endometriosis quantitative diagnostic index were observed, another 160 cases were treated with Danazol as control, also using animal model to treat with DEM and Danazol.


RESULTS
One hundred and eighty-nine cases were treated for 9 months. According to National Standards, 39 cases (20.6%) were cured, 67 cases (35.4%) were markedly effective, 67 cases (35.4%) were effective, and 16 cases (8.4%) were ineffective. Compared with 160 cases treated with Danazol for 9 months, the total effective rates were 95% and 91.5% respectively, the difference between them was insignificant. Animal experiments showed the similar results to the clinical ones.


CONCLUSIONS
SZM is a safe and effective medicine to treat endometriosis, which deserves further study and development. It is particularly helpful for diagnosis, treatment and prevention of endometriosis in the early stage.
Cai
L
L
Second Affiliated Hospital, Kunming Medical College, Yunnan (650101).
Shu
Y
Y
Xie
H
H
D000328:Adult; D000818:Animals; D001323:Autoantibodies / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004715:Endometriosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D008517:Phytotherapy; D051381:Rats; D017207:Rats, Sprague-Dawley
D001323:Autoantibodies; D004365:Drugs, Chinese Herbal