Adventitious agent issues.
Characterised cell banks are likely to be the most virologically satisfactory production system. In the past there have been numerous examples of contamination of biologicals by agents which may be difficult to detect. The certainty with which a cell can be thought satisfactory depends on the efficacy of the available methods of examination.
Minor
P
P
National Institute for Biological Standards and Control, Potters Bar, Herts, UK.
D000818:Animals; D018929:Cell Culture Techniques; D006801:Humans; D014612:Vaccines
D014612:Vaccines