title: Serial MRI findings in patient with chronic cryptococcus meningo-encephalitis.
abstract: We describe the serial changes of magnetic resonance imaging (MRI) in a patient with chronic cryptococcus meningo-encephalitis. In the subacute phase, MRI revealed a focal lesion with hyperintensity on T2-weighted image (WI) in the left thalamus. At 11 months after the onset, MRI showed a focal lesion with hyperintensity on T2-WI in the right pons that was enhanced with gadolinium (Gd). At 13 months after the onset, the lesion in the left thalamus became rim enhanced with Gd. After antifungal therapy (amphotericin B and 5-flucytosine), the rim enhancement in the left thalamus and the high signal intensity area in the right pons decreased. Cryptococcoma should be in the differential from other ring enhancing lesions.
authors.affiliation: Department of Neurology, Graduate School of Medicine and Dentistry, Okayama University, Okayama, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Narai
authors.forename: Y
authors.initials: Y
authors.lastname: Manabe
authors.forename: K
authors.initials: K
authors.lastname: Deguchi
authors.forename: K
authors.initials: K
authors.lastname: Iwatsuki
authors.forename: K
authors.initials: K
authors.lastname: Sakai
authors.forename: K
authors.initials: K
authors.lastname: Abe
mesh_terms: D002908:Chronic Disease; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D016919:Meningitis, Cryptococcal / Q000473:pathology*; D008875:Middle Aged; D011149:Pons / Q000473:pathology*; D013788:Thalamus / Q000473:pathology*