title: Serum soluble interleukin 2 receptor levels and radiological progression in early rheumatoid arthritis.
abstract: OBJECTIVE
  To investigate the association between serum soluble interleukin 2 receptor (sIL-2R) levels and radiological changes in patients with early rheumatoid arthritis (RA).
  
  
  METHODS
  sIL-2R levels from 155 patients with active RA were measured by immunoassay over a 2 year period and the associations with radiological change and other measures of disease activity were analyzed.
  
  
  RESULTS
  The area under the curve for sIL-2R is weakly associated with the change in the modified Larsen score over a 2 year period; this is weaker than the association of radiological change with serum C-reactive protein.
  
  
  CONCLUSIONS
  We found no significant association of sIL-2R levels with erosive change in early RA.
authors.affiliation: Rheumatology Department, University Hospital of Wales and School of Medicine, Cardiff, UK. jeremy.camilleri@uhw-tr.wales.nhs.uk
authors.forename: J P
authors.initials: JP
authors.lastname: Camilleri
authors.forename: N
authors.initials: N
authors.lastname: Amos
authors.forename: B D
authors.initials: BD
authors.lastname: Williams
authors.forename: P
authors.initials: P
authors.lastname: Emery
authors.forename: L A
authors.initials: LA
authors.lastname: Williams
authors.forename: J D
authors.initials: JD
authors.lastname: Jessop
mesh_terms: D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001175:Arthrography; D015415:Biomarkers / Q000097:blood; D018450:Disease Progression; D005260:Female; D006801:Humans; D007596:Joints / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000097:blood*; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D015375:Receptors, Interleukin-2