[Microscopic measurement of the surgical resection margins of laryngeal carcinomas].
OBJECTIVE
To investigate the relationship between the primary sites of laryngeal carcinomas and the surgical resection margins, to obtain quantitative data of the safe distance of surgical margins for supraglottic and glottic carcinomas.


METHODS
In this series, 33 cases of surgical specimens of laryngeal carcinomas were examined and measured microscopically by means of cutting strips of tissues adjacent to the tumor and longitudinal serial sections.


RESULTS
The pattern and extent of invasion of supraglottic carcinoma were quite different from those of glottic carcinoma. Under microscopic measurement, the tumor invasion distance in 95% of the supraglottic carcinoma samples was within 10.52 mm, while that of 95% of the glottic carcinoma samples was within 4.41 mm.


CONCLUSIONS
The local invasion of laryngeal carcinomas appears to be primary tumor site-dependent. The safe distance of surgical resection margins may be set at 12.52 mm and 6.41 mm for supraglottic and glottic carcinomas, respectively.
Sun
Y
Y
Department of Otorhinolaryngology, Medical School of Zhejiang University, Hangzhou 310009, China.
Yang
B
B
D000328:Adult; D000368:Aged; D005931:Glottis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods / Q000592:standards; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness