title: The role of deoxycytidine kinase in gemcitabine cytotoxicity.
authors.affiliation: Department Oncology, University Hospital, VU Amsterdam, The Netherlands.
authors.forename: C L
authors.initials: CL
authors.lastname: van der Wilt
authors.forename: J R
authors.initials: JR
authors.lastname: Kroep
authors.forename: A M
authors.initials: AM
authors.lastname: Bergman
authors.forename: W J
authors.initials: WJ
authors.lastname: Loves
authors.forename: E
authors.initials: E
authors.lastname: Alvarez
authors.forename: I
authors.initials: I
authors.lastname: Talianidis
authors.forename: S
authors.initials: S
authors.lastname: Eriksson
authors.forename: C J
authors.initials: CJ
authors.lastname: van Groeningen
authors.forename: H M
authors.initials: HM
authors.lastname: Pinedo
authors.forename: G J
authors.initials: GJ
authors.lastname: Peters
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000633:toxicity*; D018931:Antineoplastic Agents, Hormonal / Q000494:pharmacology; D015179:Colorectal Neoplasms / Q000201:enzymology / Q000473:pathology; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000633:toxicity*; D003842:Deoxycytidine Kinase / Q000235:genetics / Q000378:metabolism*; D003907:Dexamethasone / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005260:Female; D015870:Gene Expression; D005938:Glucocorticoids / Q000494:pharmacology; D018922:HL-60 Cells; D006801:Humans; D011493:Protein Kinase C / Q000037:antagonists & inhibitors; D012333:RNA, Messenger / Q000378:metabolism; D012264:Ribonucleotide Reductases / Q000037:antagonists & inhibitors*; D019311:Staurosporine / Q000494:pharmacology; D014407:Tumor Cells, Cultured; D020298:U937 Cells; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D018931:Antineoplastic Agents, Hormonal; D004791:Enzyme Inhibitors; D005938:Glucocorticoids; D012333:RNA, Messenger; D003841:Deoxycytidine; D003907:Dexamethasone; D012264:Ribonucleotide Reductases; D003842:Deoxycytidine Kinase; D011493:Protein Kinase C; D019311:Staurosporine; D000093542:Gemcitabine