The peptides of alpha-aminosuberic acid II. Synthesis of deamino-dicarba-eel-calcitonin sequence 1-9.
The paper describes the synthesis of Asu6-octapeptide derivatives by condensing two alternative pentapeptide fragments with Asu-containing tripeptides. After partial deprotection these linear peptides compounds are subject to cyclization experiments aimed to give the N-terminal [1-9] sequence of deamino-dicarba-eel calcitonin. This is a key substance for the semi-synthesis of the respective analogues of eel calcitonin.
Gut
V
V
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague.
Cerovský
V
V
Zertová
M
M
Körblová
E
E
Malon
P
P
Stocker
H
H
Wünsch
E
E
D000595:Amino Acid Sequence; D000600:Amino Acids, Dicarboxylic / Q000737:chemistry*; D002116:Calcitonin / Q000737:chemistry*; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry*
D000600:Amino Acids, Dicarboxylic; D010446:Peptide Fragments; C019146:2-aminosuberic acid; D002116:Calcitonin