title: Acetabular defect reconstruction with impacted morsellized bone grafts or TCP/HA particles. A study on the mechanical stability of cemented cups in an artificial acetabulum model.
abstract: In revision surgery of the acetabulum bone defects can be filled with impacted human morsellized bone grafts. Because of a worldwide limited availability of human bone, alternatives are being considered. In this study we compared the initial stability of acetabular cups after reconstructing a cavitary defect with various compositions of impacted tricalciumphosphate-hydroxyapatite (TCP/HA) particles and mixes of TCP/HA particles and human grafts in a realistic acetabulum model. Primary cemented cups and reconstructions with impacted human cancellous grafts were used as reference. A dynamic load displaced the acetabular cups superomedially. The primary cemented cups showed the highest stability. The cups with impacted human grafts produced the most displacement. All reconstructions with the TCP/HA particles showed a high stability of the cups. However, especially when using large TCP/HA particles this was probably due to a large amount of cement penetration. Mixing TCP/HA particles with human grafts seemed to decrease cement penetration. although still a high stability was obtained. In this perspective, we concluded that TCP/HA particles might be useful as a bone graft extender in the reconstruction of acetabular bone defects.
authors.affiliation: Department of Orthopaedics, University Medical Centre Nijmegen, The Netherlands.
authors.forename: S B T
authors.initials: SB
authors.lastname: Bolder
authors.forename: N
authors.initials: N
authors.lastname: Verdonschot
authors.forename: B W
authors.initials: BW
authors.lastname: Schreurs
authors.forename: P
authors.initials: P
authors.lastname: Buma
mesh_terms: D000077:Acetabulum / Q000601:surgery*; D001843:Bone Cements; D018786:Bone Substitutes / Q000737:chemistry*; D016025:Bone Transplantation; D002130:Calcium Phosphates / Q000737:chemistry*; D006801:Humans; D006882:Hydroxyapatites / Q000737:chemistry*; D008954:Models, Biological
chemical_list: D001843:Bone Cements; D018786:Bone Substitutes; D002130:Calcium Phosphates; D006882:Hydroxyapatites; C094280:hydroxyapatite-tricalciumphosphate composite