The effects of magnitude and frequency of distraction forces on tissue regeneration in distraction osteogenesis of the mandible.
Callus distraction has become an accepted treatment procedure to lengthen hypoplastic mandibles in humans. For this purpose, extraoral and intraoral devices have been applied successfully. The effects of the distraction vector, distractor stability, and rate and frequency of callus distraction on the regenerating tissues have been examined in various studies. In an experimental animal trial on pigs (n = 12), a newly developed microhydraulic osteodistractor was tested. The animals were evenly assigned to two groups to perform a continuous and noncontinuous osteodistraction of the mandible. Initially, the forces necessary to distract the pig mandibles were recorded from a noncontinuous distraction procedure; the results were then used to perform continuous bone distraction. Besides testing the new distractor, the study proved that in continuous osteodistraction, intramembranous bone regeneration occurred, whereas in noncontinuous osteodistraction the bone regeneration process followed a chondroid ossification. In continuous osteodistraction, the bone regeneration proceeded at a higher speed with the lower distraction forces compared with noncontinuous distraction, thereby reducing the consolidation period. Clinical and microscopical results are presented.
Kessler
Peter A
PA
Department of Oral and Maxillofacial Surgery, University of Erlangen-Nuremberg, Germany. Peter.kessler@mkg.imed.uni-erlangen.de
Merten
Hans A
HA
Neukam
Friedrich W
FW
Wiltfang
Jörg
J
D000818:Animals; D001696:Biomechanical Phenomena; D001861:Bone Regeneration; D005260:Female; D008334:Mandible / Q000473:pathology / Q000502:physiology* / Q000601:surgery; D019857:Osteogenesis, Distraction; D011312:Pressure; D013552:Swine