[Periodontal regeneration by application of the porous beta-TCP/BMP artificial bone to Class II furcation defects].
OBJECTIVE
To study the regeneration of periodontal tissue after the application of beta-TCP/BMP artificial bone to class II furcation defects.


METHODS
Periodontal defects were produced surgically around premolar teeth in 4 dogs. The flap surgery was performed and the root surfaces were curetted to remove the periodontal ligament and the cementum. A synthetic bioabsorble barrier manufactured from poly DL-lactide was used. The defects were divided into 3 groups (beta-TCP/BMP + PDLLA, PDLLA, control). 12 weeks after surgery, the animals were sacrificed and the teeth with their supporting periodontium were processed for light microscopic evaluation.


RESULTS
The definitive evidences of regeneration were founded both in BMP/GTR group and GTR group, but the BMP/GTR group exhibited more new bone formation, cementum deposition occupying the majority of the furcation defects than the other two groups.


CONCLUSIONS
It was concluded that the beta-TCP/BMP artificial bone can be used in GTR technique to promote periodontal regeneration.
Jia
X
X
Department of Periodontology, School of Stomatology, Hubei Medical University, Wuhan 430079, China.
Fan
M
M
Ren
T
T
D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology; D019485:Bone Morphogenetic Proteins / Q000494:pharmacology*; D001861:Bone Regeneration / Q000187:drug effects*; D018786:Bone Substitutes / Q000494:pharmacology*; D002130:Calcium Phosphates / Q000494:pharmacology*; D004285:Dogs; D017823:Furcation Defects / Q000503:physiopathology / Q000628:therapy*; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D010519:Periodontium / Q000187:drug effects* / Q000502:physiology; D016896:Treatment Outcome
D001672:Biocompatible Materials; D019485:Bone Morphogenetic Proteins; D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate; C018392:tricalcium phosphate