title: Mouse gene knockout and knockin strategies in application to alpha subunits of Gi/Go family of G proteins.
authors.affiliation: Department of Anesthesiology, School of Medicine, University of California, Los Angeles, California 90095, USA.
authors.forename: Meisheng
authors.initials: M
authors.lastname: Jiang
authors.forename: Karsten
authors.initials: K
authors.lastname: Spicher
authors.forename: Guylain
authors.initials: G
authors.lastname: Boulay
authors.forename: Angeles
authors.initials: A
authors.lastname: Martín-Requero
authors.forename: Catherine A
authors.initials: CA
authors.lastname: Dye
authors.forename: Uwe
authors.initials: U
authors.lastname: Rudolph
authors.forename: Lutz
authors.initials: L
authors.lastname: Birnbaumer
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular / Q000379:methods; D019143:Evolution, Molecular; D005091:Exons; D019206:GTP-Binding Protein alpha Subunits, Gi-Go / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D018390:Gene Targeting / Q000379:methods; D005822:Genetic Vectors; D006153:Guanosine Diphosphate / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D020962:Heterotrimeric GTP-Binding Proteins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D019426:Integrases / Q000378:metabolism; D007438:Introns; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D008969:Molecular Sequence Data; D011995:Recombination, Genetic; D015183:Restriction Mapping / Q000379:methods; D013234:Stem Cells / Q000502:physiology; D014764:Viral Proteins / Q000378:metabolism; D010566:Virulence Factors, Bordetella / Q000494:pharmacology; D016335:Zinc Fingers
chemical_list: D014764:Viral Proteins; D010566:Virulence Factors, Bordetella; D006153:Guanosine Diphosphate; D006160:Guanosine Triphosphate; C045073:Cre recombinase; D019426:Integrases; D019206:GTP-Binding Protein alpha Subunits, Gi-Go; D020962:Heterotrimeric GTP-Binding Proteins