Eradicative effect of cotrimoxazole and quinolones on non-typhoid salmonellae.
Opinions on antibiotic treatment of salmonella gastroenteritis are still different. Many authors support an opinion that antimicrobial treatment has no effect on salmonella elimination. The authors of the study have tried to prove that fluoroquinolones shorten the elimination of salmonellae and therefore they are useful not only for the treatment of salmonella gastroenteritis in immunocompromised patients to prevent sepsis and extraintestinal manifestations of the infection, but also for eradication of salmonellae in food industry workers, whose carrier state might exclude them from their work. (Tab. 3, Ref. 10.)
Wawruch
M
M
Institute of Pharmacology, Medical Faculty, Comenius University, Bratislava, Slovakia. wawruch@hotmail.com
Harnicarova
A
A
Macekova
L
L
Tisonova
J
J
Biss
B
B
Kriska
M
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D015242:Ofloxacin / Q000627:therapeutic use*; D015366:Pefloxacin / Q000627:therapeutic use*; D012189:Retrospective Studies; D012475:Salmonella / Q000187:drug effects; D012478:Salmonella Food Poisoning / Q000188:drug therapy; D012480:Salmonella Infections / Q000188:drug therapy*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D015366:Pefloxacin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D015242:Ofloxacin