Studies on the constituents of a Brazilian folk infusion. Isolation and structure elucidation of new triterpene saponins from Ilex amara leaves.
The isolation of three new triterpene saponins 3beta-O-beta-D-glucopyranosyl-(1-->3)-alpha-L-2-O-acetylarabinopyranosylolean-12-en-28-oic acid 28-O-beta-D-glucopyranosyl ester (2), 3beta-O-beta-D-glucopyranosyl-(1-->2)-alpha-L-O-arabinopyranosylurs-12-en-28-oic acid (3), and 3beta-O-beta-D-glucopyranosyl-(1-->2)-beta-D-O-galactopyranosylurs-12-en-28-oic acid (4) together with five known saponins and one flavonoid glycoside from the aqueous infusion of Ilex amara (Vellozo) Loes. leaves is reported. All structures were elucidated by spectroscopic methods, including the concerted application of one-dimensional (1H, TOCSY, 13C, and 13C DEPT NMR) and two-dimensional NMR techniques (DQF-COSY, HSQC, and HMBC).
Pezzuto de Andrade
Fabio Donisete
FD
Universidade Estadual Paulista, Instituto de Química de Araraquara, C. Postal 355, 14801-970 Araraquara, SP, Brazil.
Piacente
Sonia
S
Pizza
Cosimo
C
Vilegas
Wagner
W
D001938:Brazil; D002851:Chromatography, High Pressure Liquid; D030017:Ilex / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008519:Medicine, Traditional; D018515:Plant Leaves / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D014315:Triterpenes / Q000737:chemistry*
D012503:Saponins; D014315:Triterpenes