Cancer proteomics: from signaling networks to tumor markers.
Along with the great strides that have been made towards understanding cancer, has come a realization of the complexity of molecular events that lead to malignancy. Proteomics-based approaches, which enable the quantitative investigation of both cellular protein expression levels and protein-protein interactions involved in signaling networks, promise to define the molecules controlling the processes involved in cancer.
Simpson
R J
RJ
Laboratory, Ludwig Institute for Cancer Research/Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. richard.simpson@ludwig.edu.au
Dorow
D S
DS
D000818:Animals; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods; D023281:Genomics / Q000379:methods / Q000639:trends; D006801:Humans; D008967:Molecular Biology / Q000379:methods; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism*; D025941:Protein Interaction Mapping / Q000379:methods* / Q000639:trends; D011506:Proteins / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D020798:Two-Hybrid System Techniques
D011506:Proteins