Highly selective synthesis of heterosubstituted aromatic sulfamides.
The sulfamide functional group is increasingly relevant in both medicinal and supramolecular chemistry, yet few selective synthetic steps are available for its elaboration. We report here a mild, general, and efficient method for the selective differentiation of N-atom substituents of aromatic sulfamides. [reaction: see text]
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The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, MB-26, La Jolla, California 92037, USA.
Iovine
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Johnson
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Rebek
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D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D013457:Sulfur Compounds / Q000138:chemical synthesis* / Q000737:chemistry
D000577:Amides; D013457:Sulfur Compounds