title: Psoriasis in infancy: therapy with calcipotriene ointment.
abstract: Psoriasis in infancy is often more therapeutically challenging than atopic and seborrheic dermatitis. The generalized nature of psoriasis and the intensity of inflammation often reduce the efficacy of topical corticosteroids. Furthermore, involvement of intertriginous skin and the presence of scalp disease limit the potency of the topical steroids that can be prescribed. We report on an infant treated with topical calcipotriene for infantile psoriasis who experienced greater benefit than he had with standard corticosteroid medications. Laboratory testing for calcium metabolism was normal during the course of therapy. We conclude that calcipotriene can be a safe and effective therapy for psoriasis in early infancy.
authors.affiliation: Department of Dermatology, St. Luke's-Roosevelt Hospital Center, New York, New York 10025, USA.
authors.forename: L B
authors.initials: LB
authors.lastname: Travis
authors.forename: N B
authors.initials: NB
authors.lastname: Silverberg
mesh_terms: D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007229:Infant Welfare; D008297:Male; D009824:Ointments; D011565:Psoriasis / Q000151:congenital* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D009824:Ointments; C055085:calcipotriene; D002117:Calcitriol