title: [Clostridium difficile bacteremia].
abstract: BACKGROUND
  Extra-digestive manifestations of Clostridium difficile infection are very uncommon. Exceptional cases of C. difficile bacteremia or severe sepsis have been described in intensive care patients, demonstrating the capacity of this agent to generate generalized infection.
  
  
  METHODS
  C. difficile bacteremia occurred in a 66-year-old immunodepressed patient treated for acute myeloblastic leukemia. Bacteremia was associated with a abscess of the anal margin. Outcome was favorable after treatment with metronidosole.
  
  
  CONCLUSIONS
  Clostridium difficile is generally selected by prior antibiotic treatment. It is the principal agent of nosocomial diarrhea. In immunodepressed patients, systemic dissemination is a rare but possible development.
authors.affiliation: Service de microbiologie, CH. Valenciennes.
authors.forename: A
authors.initials: A
authors.lastname: Duthilly
authors.forename: K
authors.initials: K
authors.lastname: Blanckaert
authors.forename: B
authors.initials: B
authors.lastname: Thielemans
authors.forename: M
authors.initials: M
authors.lastname: Simon
authors.forename: C
authors.initials: C
authors.lastname: Cattoen
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000209:etiology* / Q000473:pathology; D016360:Clostridioides difficile / Q000472:pathogenicity*; D004761:Enterocolitis, Pseudomembranous / Q000150:complications*; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D008795:Metronidazole
vernacular_title: Bactériémie à Clostridium difficile.