title: Diastereoselective synthesis of 2H,5H-dihydrofurans by cobalt-mediated cycloisomerization of allyl propargyl ethers. Application to poly-THF molecules.
abstract: Allyl propargyl ethers undergo cobalt-mediated cycloisomerization reactions to form dihydrofurans in good yield and with excellent diastereoselectivity. The reaction works with a range of substrates, and its utility in synthesis is exemplified by the preparation of a bistetrahydrofuran unit. [reaction: see text]
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, QC, Canada H3A 2K6.
authors.forename: A
authors.initials: A
authors.lastname: Ajamian
authors.forename: J L
authors.initials: JL
authors.lastname: Gleason