title: Diagnosis and management of brain metastases.
abstract: In the past 15 years, significant advancement has been made in the diagnosis and treatment of brain metastases. The distinction between the management of single and multiple brain metastases is an important one. Although radiotherapy remains a mainstay of treatment, especially in multiple brain metastases, surgical resection and stereotactic radiosurgery also have their place in the management of selected patients. Rarely, interstitial radiation or chemotherapy also may be used to treat brain metastases in the setting of relapse.
authors.affiliation: Division of Hematology and Oncology, Department of Medicine, University of Kentucky Chandler Medical Center, Multidisciplinary Lung Cancer Program, Markey Cancer Center, Lexington, Kentucky, USA. smarno0@pop.uky.edu
authors.forename: S M
authors.initials: SM
authors.lastname: Arnold
authors.forename: R A
authors.initials: RA
authors.lastname: Patchell
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001918:Brachytherapy; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000556:secondary / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D009364:Neoplasm Recurrence, Local; D016634:Radiosurgery
chemical_list: D000970:Antineoplastic Agents