A case of pulmonary hypoplasia associated with intrauterine brainstem necrosis.
An infant with intrauterine brain death accompanied by pulmonary hypoplasia is reported. The fetus was delivered after 36 weeks gestation, 5 weeks after fetal movements ceased. The child died 4 h after birth. Pulmonary hypoplasia and remote brainstem necrosis associated with multicystic encephalomalacia were found at autopsy.


CONCLUSIONS
These findings suggest that damage to brainstem respiratory centres had led to pulmonary hypoplasia through the absence of fetal respiratory movement.
Endo
A
A
Department of Paediatrics, Nihon University School of Medicine, Tokyo, Japan. endo@toshima-hp.metro.tokyo.jp
Minato
M
M
Takada
M
M
Takahashi
S
S
Harada
K
K
Yamada
T
T
Takashima
S
S
D000293:Adolescent; D001344:Autopsy; D001926:Brain Death / Q000000981:diagnostic imaging / Q000473:pathology*; D001933:Brain Stem / Q000000981:diagnostic imaging / Q000473:pathology*; D004678:Encephalomalacia / Q000000981:diagnostic imaging / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities* / Q000473:pathology; D009336:Necrosis; D011247:Pregnancy; D014463:Ultrasonography