Nucleophilic trifluoromethylation using trifluoromethyl iodide. A new and simple alternative for the trifluoromethylation of aldehydes and ketones.
A novel method for nucleophilic trifluoromethylation of aldehydes and ketones, based on photoinduced reduction of trifluoromethyl iodide by tetrakis(dimethylamino)ethylene (TDAE), is presented. [reaction: see text]
Aït-Mohand
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Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA.
Takechi
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Médebielle
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Dolbier
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