[Prevalence of hiatal hernia and chronic esophagitis in adult asthmatic patients].
BACKGROUND
The association among asthma, hiatus hernia, oesophagitis and gastro-oesophageal reflux has been reported as etiologic factor that alters the clinical evolution of the asthma.


METHODS
Prospective, longitudinal and comparative study was developed. 90 patients were incoming with persistent light and moderate asthma, of allergic etiology. By the 6 months of immune-allergic treatment the clinical answer was valued being classified in two groups: Group A: 40 patients with intermittent light asthma and group B: 50 patients with persistent severe moderate asthma. In both groups they were submitted to an endoscopy for the diagnosis of esophageal pathology, with biopsies in the 3 esophageal thirds. They registered symptoms of gastro-oesophageal reflux.


RESULTS
72 women and 28 men, age average 35.9 years. There was hiatus hernia in 33 patients, 12 of the group A and 21 of the B. Upper oesophagitis in 21 patients, 8 of the group A and 13 of the B. Symptoms of gastro-oesophageal reflux in 71 patients, 29 of the group A and 42 of the B. The association among hiatus hernia, oesophagitis and gastro-oesophageal reflux was observed in 12 patients, 2 of the group A and 10 of the B (p < 0.05).


CONCLUSIONS
The association of symptoms among gastro-oesophageal reflux, hiatus hernia and upper oesophagitis, is bigger in the patients with bad answer to the anti-asthmatic treatment; they are justified to endoscopy study and biopsies of the upper oesophagus (in the group of patients with bad response and symptoms of gastro-oesophageal reflux) when 24 hours pH-monitoring is not available.
Mogica Martínez
M D
MD
Servicio de alergia e inmunologia clínica, Hospital de Especialidades, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social.
Paredes Cruz
E
E
Tenorio Pastrana
M A
MA
Rodríguez Castellón
J
J
Molina Ortiz
C
C
del Rosario Canseco Raymundo
M
M
López Durán
J L
JL
Becerril Angeles
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000453:epidemiology; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D015897:Comorbidity; D004351:Drug Resistance; D004942:Esophagitis, Peptic / Q000453:epidemiology* / Q000209:etiology; D004945:Esophagoscopy; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000453:epidemiology; D006551:Hernia, Hiatal / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D007167:Immunotherapy; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D015995:Prevalence; D012720:Severity of Illness Index; D012907:Smoking / Q000453:epidemiology; D016896:Treatment Outcome
D018927:Anti-Asthmatic Agents
Prevalencia de hernia hiatal y esofagitis crónica en pacientes asmáticos adultos.