title: The daily pattern of heart rate, body temperature, and locomotor activity in guinea pigs.
abstract: We studied the characteristics of the rhythmicity of heart rate (HR), body temperature (BT), and locomotor activity (LA) in conscious and unrestrained guinea pigs using a telemetry system. HR and/or LA in some guinea pigs clearly showed circadian rhythms, but in others there were no significant daily patterns; BT did not show significant daily rhythms. These results suggest that guinea pigs might have different individual characteristics of rhythmicity, and we should, therefore, be careful when using guinea pigs in chrono-biomedical research. We believe that the results of this study may be useful for future biomedical studies using guinea pigs.
authors.affiliation: Department of Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Akita
authors.forename: K
authors.initials: K
authors.lastname: Ishii
authors.forename: M
authors.initials: M
authors.lastname: Kuwahara
authors.forename: H
authors.initials: H
authors.lastname: Tsubone
mesh_terms: D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D002940:Circadian Rhythm; D006168:Guinea Pigs / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D008124:Locomotion / Q000502:physiology*; D008297:Male; D013686:Telemetry / Q000662:veterinary