title: [Significance of platelet CD62p, CD63 assessment in type 2 diabetes mellitus patients with blood stasis].
abstract: OBJECTIVE
  To study the relationship between blood stasis and platelet activation and the influential factors on the latter in type 2 diabetes mellitus (DM) patients.
  
  
  METHODS
  Platelet CD62p, CD63 expressions were determined in 30 patients of type 2 DM with blood stasis, 27 patients of type 2 DM without blood stasis and 20 normal controls by flow cytometry.
  
  
  RESULTS
  CD62p, CD63 levels were significantly higher in type 2 DM with blood stasis group than that without blood stasis group and in normal controls. CD62p was positively correlated with CD63, while positive correlation existed between HbA1c, LDL-C and CD62p in DM patients with blood stasis.
  
  
  CONCLUSIONS
  The increased level of platelet activation was the primary molecular basis in type 2 DM. It was important to perform the Syndrome Differentiation of blood stasis and treatment of activating blood circulation to remove blood stasis in type 2 DM.
authors.affiliation: General Hospital of Jinan Military Region, Jinan (250031).
authors.forename: Z
authors.initials: Z
authors.lastname: Jiang
authors.forename: S
authors.initials: S
authors.lastname: Zhang
authors.forename: T
authors.initials: T
authors.lastname: Kou
mesh_terms: D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000097:blood*; D001792:Blood Platelets / Q000378:metabolism*; D015815:Cell Adhesion Molecules / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D019007:P-Selectin / Q000097:blood*; D010980:Platelet Membrane Glycoproteins; D060149:Tetraspanin 30
chemical_list: D015703:Antigens, CD; C554586:CD63 protein, human; D015815:Cell Adhesion Molecules; D019007:P-Selectin; D010980:Platelet Membrane Glycoproteins; D060149:Tetraspanin 30