[Percutaneous transluminal septal myocardial ablation in patients with hypertrophic obstructive cardiomyopathy: immediately and middle-term follow-up results].
OBJECTIVE
To evaluate the immediate and follow-up results of percutaneous transluminal septal myocardial ablation (PTSMA) in patients with hypertrophic obstructive cardiomyopathy (HOCM).


METHODS
15 patients with HOCM refractory to medication successfully underwent PTSMA under myocardial contrast echocardiography.


RESULTS
The left ventricular outflow gradients (LVOTG) were reduced significantly (77.93 +/- 22.00) mm Hg to (14.8 +/- 15.0) mm Hg (P < 0.0001) immediately with a mean decrease of (5.75 +/- 2.87) mm Hg (P < 0.001) in left ventricular end diastolic pressure. The scores of SAM and mitral regurgition During a mean of 8.6 +/- 3.8(6-22) months follow-up, the patients heart function (NYHA) were greatly improved(3.4 +/- 0.5 vs 1.1 +/- 0.4, P < 0.001), and disappearance of angina pectoris, and exercise endurance improvement with steady hemodynamic improvement.


CONCLUSIONS
PTSMA is effectively non-surgical treatment method for drug-refractory patients with HOCM.
Jiang
T
T
Departmen of Cardiology, Beijing Anzhen Hospital, Beijing 100029, China.
Wu
X
X
Jia
C
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D006328:Cardiac Catheterization / Q000379:methods*; D002312:Cardiomyopathy, Hypertrophic / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome