[Adrenergic innervation of the myocardium in patients with cardiac syndrome X].
11 syndrome X patients and 8 healthy controls were investigated by myocardial scintigraphy (SPECT) with 123-I-MIBG. Regional defects in cardiac 123-I-MIBG uptake were found in 90% syndrome X patients. Total cardiac 123-I-MIBG uptake appeared significantly higher in syndrome X patients. Perfusion defects on stress 99m-Tc-MIBI scintigraphy were found in 10 syndrome X patients who had also abnormal 123-I-MIBG scintigrams. It is suggested that impairment of efferent cardiac adrenergic nerve fiber function in syndrome X patients may contribute to pathophysiologic and clinical features of syndrome X.
Shevchenko
Iu L
IuL
Tyrenko
V V
VV
Nikitin
A E
AE
Belevitin
A B
AB
Svistov
A S
AS
D019797:3-Iodobenzylguanidine; D000320:Adrenergic Fibers / Q000502:physiology*; D000328:Adult; D005260:Female; D006321:Heart / Q000294:innervation* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D017566:Microvascular Angina / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008875:Middle Aged; D009206:Myocardium; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine; D017256:Technetium Tc 99m Sestamibi
Issledovanie adrenergicheskoĭ innervatsii miokarda u bol'nykh kardial'nym sindromom X.