[Unexpected diagnosis of thorotrast-induced cirrhosis].
It is presented the clinical case of a 73 year old man admitted to hospital with dyspnea and productive cough. Clinico-instrumental investigations demonstrated monolateral pleural effusion and ascites in a severe cirrhotic chronic liver failure. After evacuation of the pleural and peritoneal effusion, chest radiography showed the presence of a double accumulation of radiopaque material in left cervical region and in left paramediastinic site. Chest and abdominal CT scan showed a systemic accumulation of this material in liver, spleen and glands. The characteristics of the iperreflecting substance accumulated were compatible with that of Thorotrast. In the mean time, a prostate cancer with skeletal metastases was diagnosed. Despite therapy, the chronic liver failure causes a rapid deterioration of clinical conditions, with irreversible hepatic coma and death.
Bo
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Sezione di Geriatria, Dipartimento di Discipline Medico-chirurgiche, Università, Torino.
Grassone
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D
Fabris
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F
D000368:Aged; D003287:Contrast Media / Q000009:adverse effects*; D017809:Fatal Outcome; D006801:Humans; D008103:Liver Cirrhosis / Q000139:chemically induced*; D017093:Liver Failure / Q000139:chemically induced*; D008297:Male; D013911:Thorium Dioxide / Q000009:adverse effects*
D003287:Contrast Media; D013911:Thorium Dioxide
Una inattesa diagnosi di cirrosi da Thorotrast.