[A rapid method for detecting interconnections between functionally and/or evolutionary close biological sequences].
It is now common practice to retrieve, by key words, highly specialized selections of sequences from general-purpose databases such as EMBL, GenBank, etc. The sequences included in a selection are often interconnected, which means that there are duplications, embeddings, intersections, homology, common structural elements. Knowledge of these interconnections is necessary for further processing of the sequences. We propose a rapid (single scan) method for identification of such interconnections by means of complexity analysis that generalizes the Lempel-Ziv approach. Analysis of a selection of 5'-flanking regions of vertebrate growth hormone genes from EMBL is presented as an example.
Gusev
V D
VD
Department of Computer Science, Cardiff University, PO. Box 916, Cardiff, CF24 3XF, UK. gusev@math.nsc.ru
Nemytikova
L A
LA
Chuzhanova
N A
NA
D030561:Databases, Nucleic Acid; D019143:Evolution, Molecular; D012091:Repetitive Sequences, Nucleic Acid
Bystryĭ metod vyiavleniia vzaimosviazeĭ v podborkakh funktsional'no i/ili évoliutsionno blizkikh biologicheskikh tekstov.