Effect of a randomized, controlled trial of exercise on mood and physical function in individuals with fibromyalgia.
OBJECTIVE
To evaluate the effect of exercise on mood and physical function in individuals with fibromyalgia.


METHODS
Subjects were randomly assigned to an exercise (EX) or control (CTL) group. EX subjects participated in 3 30-minute exercise classes per week for 23 weeks. Subjects were tested at entry and at 6, 12, and 23 weeks. Tests included the Beck Depression Inventory (BDI), 6-minute walk, State-Trait Anxiety Inventory (STAI), Mental Health Inventory (MHI), Fibromyalgia Impact Questionnaire (FIQ), Arthritis Self-Efficacy Scale (ASES), and a measure of tender points and knee strength.


RESULTS
Fifty subjects (27 EX, 23 CTL) completed the study, and 31 (15 EX, 16 CTL) met criteria for efficacy analyses. In efficacy analyses, significant improvements were seen for EX subjects in 6-minute walk distances, BDI (total, cognitive/ affective), STAI, FIQ, ASES, and MHI (3 of 5 subscales) scores. These effects were reduced but remained during intent-to-treat analyses.


CONCLUSIONS
Exercise can improve the mood and physical function of individuals with fibromyalgia.
Gowans
S E
SE
Department of Rehabilitation Services, University Health Network, Toronto General Hospital, Ontario, Canada. sue.gowans@uhn.on.ca
deHueck
A
A
Voss
S
S
Silaj
A
A
Abbey
S E
SE
Reynolds
W J
WJ
D000339:Affect; D005081:Exercise Therapy; D005260:Female; D005356:Fibromyalgia / Q000523:psychology* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome