Metabolism of the food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes.
Langouët
S
S
INSERM U456, Faculté de Pharmacie, Rennes, France.
Welti
D H
DH
Kerriguy
N
N
Fay
L B
LB
Guengerich
F P
FP
Guillouzo
A
A
Turesky
R J
RJ
D019388:Cytochrome P-450 CYP1A2 / Q000378:metabolism*; D022781:Hepatocytes / Q000166:cytology / Q000378:metabolism; D006801:Humans; D015394:Molecular Structure; D009153:Mutagens / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D010084:Oxidation-Reduction; D011810:Quinoxalines / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D009153:Mutagens; D011810:Quinoxalines; C036990:2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline; D019388:Cytochrome P-450 CYP1A2