Genetic analysis of HIV type 2 from Ghana and Guinea-Bissau, West Africa.
The phylogenetic variability of part of the long terminal repeat (LTR) region of HIV-2 strains isolated in 1995 from five individuals residing in Bissau, the capital city of Guinea-Bissau, and collected from seven persons from Kumasi, Ghana in 1996-1997, was analyzed. All Guinean samples and all but one Ghanaian sample clustered with HIV-2 subtype A. One Ghanaian sample (14%) was classified as HIV-2 subtype B. This study adds to previous reports on HIV-2 subtype distribution in West Africa indicating local prevalence of HIV-2 subtype B in Ivory Coast and neighboring Ghana.
Ishikawa
K
K
AIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama Shinjuku, Tokyo 162-8640, Japan. kishikaw@nih.go.jp
Janssens
W
W
Banor
J S
JS
Shinno
T
T
Piedade
J
J
Sata
T
T
Ampofo
W K
WK
Brandful
J A
JA
Koyanagi
Y
Y
Yamamoto
N
N
Canas-Ferreira
W F
WF
Adu-Sarkodie
Y
Y
Kurata
T
T
D004279:DNA, Viral / Q000032:analysis; D005869:Ghana / Q000453:epidemiology; D006169:Guinea-Bissau / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology; D016325:HIV Long Terminal Repeat / Q000235:genetics*; D015498:HIV-2 / Q000145:classification* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA
D004279:DNA, Viral