Management of oral disease prior to radiation therapy.
Radiation therapy for malignant tumors of the head and neck is associated with significant side effects involving the oral cavity. For example, radiation therapy leads to reduced vascularity and oxygen tension of the oral hard and soft tissues and also to salivary gland dysfunction. These changes increase the risk of dental decay and oral infections and lead to reduced healing capacity following oral surgery procedures. A severe complication of radiation therapy is osteoradionecrosis of the jaw bone. The purpose of this paper is to review preradiation oral examination and treatment. Patient management regarding oral disease prior to radiation therapy has to accomplish a number of goals: (1) to identify existing oral disease and potential risk of oral disease, (2) to remove infectious dental/oral foci before the start of radiation therapy, (3) to prepare the patient for the expected side effects with information about them, (4) to establish an adequate standard of oral hygiene to meet the increased challenge, (5) to provide a plan for maintaining oral hygiene and fluoride treatment, for oral rehabilitation, and for follow-up and (6) to inform the patient about the availability of any financial support for dental treatment, and finally (7) to establish the necessary multidiciplinary collaboration within the health care system so that oral symptoms and sequelae before, during and after the radiation therapy can be reduced or alleviated. The methods used to accomplish these goals may vary between cancer centers. Each center should have a multidisciplinary team to handle such problems. After the end of radiation therapy most of the dental treatments in our patients are done by private dentists, except for some oral surgery procedures, which are performed in hospital. In our experience, the major challenge in this process is related to (1) informing of the patient, (2) timing the coordination between all the health care workers involved, (3) establishing an adequate schedule for dental treatment and follow-up, and (4) securing patient compliance to prevent or reduce the oral side effects.
Schiødt
Morten
M
Department of Oral and Maxillofacial Surgery, Copenhagen County University Hospital Glostrup, Denmark. mosc@glostruphosp.kbhamt.dk
Hermund
Niels Ulrich
NU
D003729:Dental Care / Q000592:standards; D004307:Dose-Response Relationship, Radiation; D006258:Head and Neck Neoplasms / Q000150:complications / Q000532:radiotherapy; D006801:Humans; D009059:Mouth Diseases / Q000532:radiotherapy*; D009061:Mouth Mucosa / Q000528:radiation effects*; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D009910:Oral Hygiene / Q000592:standards; D010353:Patient Education as Topic; D011878:Radiotherapy; D012307:Risk Factors; D013997:Time Factors; D014076:Tooth Diseases / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D016896:Treatment Outcome