[Influence of feiliuping No. 2 on platelet surface glycoprotein expression in mid-late stage lung cancer patients].
OBJECTIVE
To explore the influence of Feiliuping NO. 2 (FLP), a Chinese herbal preparation for reinforcing Qi, nourishing Yin, activating blood circulation and detoxifying, on surface glycoprotein expression (SGPE) and activated condition of platelet in mid-late stage lung cancer patients.


METHODS
Changes of platelet surface expression of CD41/CD42a, CD36/TSP, CD62/CD63, CD9 and CD31 were measured before and after FLP treatment by using flow cytometer in 30 cases of mid-late stage lung cancer.


RESULTS
The SGPE and activated condition of platelet in mid-late stage lung cancer patients were significantly higher than those of healthy person, and both could be reduced partly by FLP.


CONCLUSIONS
FLP could influence the SGPE and activate condition of platelet in lung cancer patients.
Zhang
P
P
Guang'anmen Hospital, China Academy of TCM, Beijing (100053).
Piao
B
B
Sun
G
G
D000328:Adult; D000368:Aged; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood* / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000378:metabolism; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000378:metabolism; D010980:Platelet Membrane Glycoproteins / Q000378:metabolism*
D004365:Drugs, Chinese Herbal; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D019038:Platelet Glycoprotein GPIb-IX Complex; D010980:Platelet Membrane Glycoproteins