[The effect of prednisolone on the regeneration of condylar cartilage of the rabbit].
OBJECTIVE
To investigate the effect of the prednisolone on the condylar cartilage regeneration.


METHODS
A full-thickness defect without penetrating the subchondral compact bone was made in the condylar cartilage of the adult rabbits, and prednisolone(25 mg) was applied locally. The reparative tissue was observed histologically and histochemically.


RESULTS
The compact bone in the area of the defect of the condylar cartilage showed hyperplasia, and the defect was filled with compact bone at the end of twelve weeks.


CONCLUSIONS
Prednisolone is able to repair the defect of the condylar cartilage.
Yao
X
X
Center for TMD, School of Stomatology, Beijing Medical University, Beijing 100081, China.
Ma
X
X
Zhang
Z
Z
D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects; D002358:Cartilage, Articular / Q000187:drug effects* / Q000293:injuries / Q000503:physiopathology; D005938:Glucocorticoids / Q000494:pharmacology*; D008297:Male; D008335:Mandibular Condyle / Q000187:drug effects* / Q000293:injuries / Q000503:physiopathology; D011239:Prednisolone / Q000494:pharmacology*; D011817:Rabbits; D013997:Time Factors
D005938:Glucocorticoids; D011239:Prednisolone