title: [Influence of flavonoid of Astragalus membranaceus's stem and leaves on the function of cell mediated immunity in mice].
abstract: OBJECTIVE
  To investigate the immune regulation of flavonoid of Astragalus membranaceus's stem and leaves (FAM).
  
  
  METHODS
  Changes of total T cell count and subsets in mice were determined by monoclonal antibody assay before and after treatment with FAM, and the LAK activity was tested simultaneously by isotope technique.
  
  
  RESULTS
  FAM could promote the proliferation of lymphocytes induced by ConA, raise the T cell count and regulate the T cell subsets disorder, elevate the LAK activity induced by IL-2.
  
  
  CONCLUSIONS
  FAM possesses the effect of immune stimulation and immune regulation in treating immunosuppressive mice. This study provides the experimental basis for clinical application of FAM.
authors.affiliation: Heilongjiang University of TCM, Harbin (150040).
authors.forename: Y
authors.initials: Y
authors.lastname: Jiao
authors.forename: J
authors.initials: J
authors.lastname: Wen
authors.forename: X
authors.initials: X
authors.lastname: Yu
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D027883:Astragalus Plant; D027885:Astragalus propinquus; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology*; D005260:Female; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D015979:Killer Cells, Lymphokine-Activated / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D018520:Plant Shoots / Q000737:chemistry; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; C027492:Huang Qi