Interrelation between different stages of atherogenesis in rabbits with high and low resistance to dyslipidemia.
Changes in lipid metabolism and morphofunctional state of neuroregulatory and circulatory systems during dyslipidemia were studied in rabbits with high and low resistance to this risk factor. It was found that impairment of neuroregulatory systems plays an important role in initiation and progression of microcirculatory disorders and atherosclerosis. Atherogenic index is the most informative parameter for evaluation of pathological changes in the vascular system during dyslipidemia.
Kobozeva
L P
LP
Laboratory of Experimental Pathomorphology, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow.
Klimenko
E D
ED
Michunskaya
A B
AB
Pozdnyakov
O P
OP
D000818:Animals; D001161:Arteriosclerosis / Q000378:metabolism* / Q000473:pathology*; D006949:Hyperlipidemias / Q000473:pathology*; D007031:Hypothalamus / Q000378:metabolism; D050356:Lipid Metabolism; D008297:Male; D010902:Pituitary Gland / Q000378:metabolism; D011817:Rabbits; D012307:Risk Factors; D013997:Time Factors