[Serum copper levels in obesity: a study of 32 cases].
Abnormalities of copper distribution in tissues and serum has been described in obese subjects. In this prospective study, we evaluated the seric level of copper by atomic absorption in a group of 32 obese (BMI > or = 30 kg/m2) compared to a group of 32 healthy subjects. We have noted an elevation of serum copper in obese with a middle level of 133 mg/dl significantly superior to the middle level of serum copper of healthy subjects, 108 mg/dl (p < 0.001). In another hand, we have noticed that the levels of serum cooper rise with the BMI. In fact, 58.3% of the obese that have a BMI > or = 40 kg/m2 show a high concentration of serum copper although only 5% of obese with BMI < 40 kg/m2 show this high concentration. This work must be completed by the determination of ceruloplasmin levels in a larger group of obese in order to establish correlations between the serum ceruloplasmin levels, the serum copper levels and the obesity.
Omar
S
S
Service de Biologie Clinique, Institut Salah Azaïez, Bab Saadoun.
Abdennebi
M
M
Ben Mami
F
F
Ghanem
A
A
Azzabi
S
S
Hedhili
A
A
Zouari
B
B
Achour
A
A
Guemira
F
F
D000328:Adult; D015992:Body Mass Index; D002570:Ceruloplasmin / Q000032:analysis; D003300:Copper / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000150:complications* / Q000503:physiopathology
D003300:Copper; D002570:Ceruloplasmin
Le cuivre serique chez l'obese: une etude a propos de 32 cas.