title: Intracranial aneurysms: experience in treating 500 patients.
abstract: OBJECTIVE
  To summarize the experience in surgical treatment of patients with intracranial aneurysms.
  
  
  METHODS
  The measures used in the treatment of 500 patients with intracranial aneurysms were retrospectively reviewed with regard to timing of surgery, induced-hypotensive anesthesia, brain protection combined with temporal occlusion of the feeding artery, dynamically monitoring of transcranial Doppler ultrasound, antivasospasm treatment, techniques of direct surgery, and endovascular embolization.
  
  
  RESULTS
  In 465 patients undergoing surgery, intraoperative rupture was observed in 27(6.2%), postoperative death in 13 (2.7%), hemipalsy in 8(2.2%), and vegetative state in 2 (5.0%). The operative mortality was 3.8% in 210 patients before 1990, while 1.9% in 255 patients after 1990.
  
  
  CONCLUSIONS
  The outcome of patients with intracranial aneurysms can be markedly improved by comprehensive measures.
authors.affiliation: Department of Neurosurgery, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Ding
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.forename: A
authors.initials: A
authors.lastname: Duan
authors.forename: Y
authors.initials: Y
authors.lastname: Hua
authors.forename: J
authors.initials: J
authors.lastname: Cao
authors.forename: R
authors.initials: R
authors.lastname: Zhao
authors.forename: G
authors.initials: G
authors.lastname: Xu
authors.forename: J
authors.initials: J
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies