title: [The biological distribution of thrombosis in the year 2000].
abstract: Acquired or genetic risk factors for thrombosis are present in about fifty per cent of the patients with venous thromboembolic disease. In order to evaluate the contribution of genetic defects in the pathogenesis of thrombosis, the laboratory investigation will include search for the factor V Leiden and prothrombin Leiden mutations, and for antithrombin, protein C and protein S hereditary deficiencies. Search for antiphospholipid antibodies and factor VIII plasma levels measurements will be also performed.
authors.affiliation: Service d'Hématologie biologique A-Hôpital Européen Georges Pompidou, 20, rue Leblanc, 75908 Paris, France. martine.alhenc-gelas@hop.egp.ap-hop-paris.fr
authors.forename: M
authors.initials: M
authors.lastname: Alhenc-Gelas
mesh_terms: D017152:Antibodies, Antiphospholipid / Q000097:blood; D005169:Factor VIII / Q000032:analysis; D006801:Humans; D009154:Mutation; D012307:Risk Factors; D013927:Thrombosis / Q000175:diagnosis / Q000235:genetics / Q000276:immunology; D020246:Venous Thrombosis / Q000175:diagnosis / Q000235:genetics / Q000276:immunology
chemical_list: D017152:Antibodies, Antiphospholipid; D005169:Factor VIII
vernacular_title: Le bilan biologique de thrombose en l'an 2000.