title: [The case of Wegener's granulomatosis of the nose, larynx and ear].
abstract: We have described a rare case of Wegener's granulomatosis in our 41-year old patient, located in the nose, larynx and ear. The disease usually presents as a triad of respiratory, vascular and kidney location. It may occur as a rapid or indolent progress. We have shown in our paper diagnostic difficulties connected with this disease. The biopsies of involved organs and blood tests are the best steps of establish proper diagnosis. Antineutrophil cytoplasmic antibodies (ANCA) are typical markers of Wegeners's granulomatosis. The conservative therapy including immunosuppression and surgical treatment (laserotherapy) are main methods of management. Our patient was given antibiotic therapy, and immunosuppressive therapy. Her condition improved during the first hospitalisation. Remission lasted very short, and she was admitted to the hospital again and underwent intensive investigations and therapy. We observed dyspnea caused by subglottic stenosis. The histologic examination of the tracheal mucosa showed granulomatous inflammation. After intensive therapy our patient felt better. She has been in our records till now, we observe no progress of disease. Finally, we would like to pay attention to the fact, that early diagnosis is important to prevent complications such subglottic stenosis which can lead to death.
authors.affiliation: Oddział Laryngologii Szpitala MSWiA w Olsztynie.
authors.forename: I
authors.initials: I
authors.lastname: Wojciechowski
authors.forename: S
authors.initials: S
authors.lastname: Piotrowski
authors.forename: I
authors.initials: I
authors.lastname: Zaniewska-Kulesza
authors.forename: E
authors.initials: E
authors.lastname: Komorowska
mesh_terms: D000328:Adult; D004432:Ear, Middle / Q000473:pathology* / Q000601:surgery; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007830:Larynx / Q000473:pathology* / Q000601:surgery; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery
vernacular_title: Przypadek choroby Wegenera z lokalizacja w obrebie nosa, ucha i krtani.