[Study on the relationship between the bond absorption of chronic periapical periodontitis and PGE2 and TXB2].
OBJECTIVE
To further study the mechanisms of damages and resorption of bone in chronic periapical periodontitis.


METHODS
The quantities and distribution of PGE2 and TXB2 in apical granuloma of chronic periapical periodontitis were analyzed using radio immunization analysis.


RESULTS
The quantities of PGE2 and TXB2 in apical granuloma of chronic periapical periodontitis were significantly (P < 0.05) higher than those in controls.


CONCLUSIONS
The PGE2 has the close relation with the bone resorption of chronic periapical periodontitis during the whole process. Meanwhile, TXB2 also has certain relation with the bond absorption. The quantities of PGE2 and TXB2 are imbalanced.
Chen
J
J
Hangzhou Second People's Hospital, Hangzhou 310015.
Chen
Z
Z
Zhang
L
L
D000293:Adolescent; D000328:Adult; D001862:Bone Resorption / Q000209:etiology*; D002908:Chronic Disease; D015232:Dinoprostone / Q000032:analysis*; D005260:Female; D006099:Granuloma / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010485:Periapical Periodontitis / Q000150:complications* / Q000378:metabolism; D011863:Radioimmunoassay; D013929:Thromboxane B2 / Q000032:analysis*
D013929:Thromboxane B2; D015232:Dinoprostone