[Change of plasma cellular fibronectin values in hypertension disorders of pregnancy].
OBJECTIVE
To investigate change of plasma values of cellular fibronectin (cFN) in pregnant women with hypertension diseases.


METHODS
One hundred and twelve pregnant women were assigned into five groups according to definition of hypertension diseases in pregnancy published by the National Working Group on Hypertension. The values of plasma cFN were measured with enzyme-link immunosorbent assay (ELISA). Statistical tests were performed with Variance Analysis (Scheff's post-hoc).


RESULTS
Plasma cFN values in women of preeclamptic group (12.25 +/- 4.00) mg/L and superimposed preeclamptic group (11.33 +/- 3.74) mg/L were both significantly higher than those of normal group (5.06 +/- 1.33) mg/L (P < 0.01). However, cFN values were not statistically different between women of chronic hypertension or transient hypertension and of normal women (P > 0.05).


CONCLUSIONS
The clinical detection of plasma cFN values appears to be useful in differentiating various hypertension diseases of pregnancy and in selection of relevant treatment regimen.
Zhang
M
M
Department of Obstetrics and Gynecology, Third Affiliated Hospital, Hunan Medical University, Changsha 410013, China.
Xue
M
M
D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D006973:Hypertension / Q000097:blood*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood*
D005353:Fibronectins