Oxidant injury in coronary heart disease (Part-I).
Oxidative stress damages the heart through a series of reactions beginning with lipid peroxidation, the main process behind atherosclerosis. Antioxidant supplementation has some beneficial effects by binding with metal ions or catalysts to prevent oxidative lipid peroxidation and chain production.
Pandya
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Department of Medicine, Maryland General Hospital, 827 Linden Avenue, Baltimore, MD 21201, USA.
D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000378:metabolism; D001161:Arteriosclerosis / Q000378:metabolism / Q000473:pathology; D003327:Coronary Disease / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000378:metabolism / Q000473:pathology; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation; D009206:Myocardium / Q000378:metabolism*; D018384:Oxidative Stress
D000975:Antioxidants; D005609:Free Radicals