title: Nuclear xeno-sensors as receptors for cholestatic bile acids: the second line of defense.
authors.forename: Hans H
authors.initials: HH
authors.lastname: Bock
authors.forename: Frank
authors.initials: F
authors.lastname: Lammert
mesh_terms: D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases; D001647:Bile Acids and Salts / Q000378:metabolism*; D002779:Cholestasis / Q000209:etiology / Q000628:therapy; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006801:Humans; D006900:Hydroxylation; D008095:Lithocholic Acid / Q000378:metabolism / Q000633:toxicity; D008107:Liver Diseases / Q000209:etiology / Q000628:therapy; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D000077297:Pregnane X Receptor; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics / Q000502:physiology*; D011987:Receptors, Steroid / Q000235:genetics / Q000502:physiology*
chemical_list: D001647:Bile Acids and Salts; D000077297:Pregnane X Receptor; D018160:Receptors, Cytoplasmic and Nuclear; D011987:Receptors, Steroid; D008095:Lithocholic Acid; D003577:Cytochrome P-450 Enzyme System; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating