title: Placental insufficiency and maternal death caused by advanced stage of breast cancer in third trimester.
abstract: We describe a case with placental, and general metastases, resulting in transient intrauterine and general hypoxia, and with additionally clinical features similar to HELLP syndrome. A patient in the third trimester with dyspnea at rest developed right heart failure during c-section. During emergency thoracotomy the patient went into generalized shock and died after intense CPR. Placental insufficiency was based on a multilocal metastatic event, decreasing the utero-placental perfusion.
authors.affiliation: Department of Obstetrics & Gynecology, University of Vienna, General Hospital, Währinger Gürtel 18-20, A-1090, Vienna, Austria. rainer.lehner@akh-wien.ac.at
authors.forename: R
authors.initials: R
authors.lastname: Lehner
authors.forename: H
authors.initials: H
authors.lastname: Strohmer
authors.forename: S
authors.initials: S
authors.lastname: Jirecek
authors.forename: N
authors.initials: N
authors.lastname: Goharkhay
authors.forename: B
authors.initials: B
authors.lastname: Tringler
authors.forename: M
authors.initials: M
authors.lastname: Barrada
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000150:complications* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D009362:Neoplasm Metastasis / Q000473:pathology*; D010927:Placental Insufficiency / Q000209:etiology* / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D011263:Pregnancy Trimester, Third