[Spongiform encephalitis].
The authors present a personal interpretation of the pathogeny of prionic processes, showing the role played by heredity. They also present the very surprising fact that a protein codified by a mutant gene can act as transmissible agent in a serious illness opening new chapters to the pathology of a series of important diseases. This is a completely new perspective in the biology.
Domínguez Carmona
M
M
Domínguez de la Calle
M
M
D000367:Age Factors; D000368:Aged; D000818:Animals; D002417:Cattle; D003062:Codon; D007562:Creutzfeldt-Jakob Syndrome / Q000235:genetics / Q000473:pathology; D006224:Cricetinae; D004195:Disease Models, Animal; D005091:Exons; D020022:Genetic Predisposition to Disease; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D009154:Mutation; D011110:Polymorphism, Genetic; D018621:PrPC Proteins / Q000096:biosynthesis / Q000235:genetics* / Q000378:metabolism; D017096:Prion Diseases / Q000235:genetics* / Q000473:pathology / Q000635:transmission; D011328:Prions / Q000235:genetics*; D051381:Rats; D012608:Scrapie / Q000235:genetics; D012756:Sheep; D013569:Synapses / Q000378:metabolism; D013997:Time Factors
D003062:Codon; D018621:PrPC Proteins; D011328:Prions
Encefalitis espongiformes.