title: Effects of acidum vitamin A on tyrosinase activity.
abstract: OBJECTIVE
  To investigate the effect of acidum vitamin A on tyrosinase activity and provide experimental evidence for therapy of pigment disorder of skin.
  
  
  METHODS
  Tyrosinase activity was estimated by measuring the rate of oxidation of DL-dopa.
  
  
  RESULTS
  The levels of tyrosinase activity in the acidum vitamin A group were significantly greater than those of the control group (P < 0.01).
  
  
  CONCLUSIONS
  Tyrosinase activity can be increasingly induced by acidum vitamin A.
authors.affiliation: Department of Dermatology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: W
authors.initials: W
authors.lastname: Zhu
mesh_terms: D006801:Humans; D014442:Monophenol Monooxygenase / Q000235:genetics / Q000378:metabolism*; D010858:Pigmentation / Q000187:drug effects; D018168:Receptors, Retinoic Acid / Q000187:drug effects / Q000502:physiology; D014212:Tretinoin / Q000494:pharmacology*
chemical_list: D018168:Receptors, Retinoic Acid; D014212:Tretinoin; D014442:Monophenol Monooxygenase