Use of rabies vaccines after reconstitution and storage.
Storing freshly reconstituted purified chick embryo rabies vaccine at 4 degrees C for 1 week allowed use of <1 ampoule of 1.0 mL for 1 patient for day 0, 3, and 7 immunizations, representing considerable savings in vaccine and also possibly allowing use of this cost-saving regimen in centers that see <1 rabies-exposed patient daily. The 90-day booster dose mandated in the current intradermal regimen may not be necessary if the day 28 dose is doubled, eliminating 1 clinic visit at no additional cost in vaccine.
Khawplod
Pakamatz
P
Queen Saovabha Memorial Institutes, Thai Red Cross Society and Department of Medicine, King Chulalongkorn University Hospital, Bangkok, Thailand.
Tantawichien
Tanpetch
T
Wilde
Henry
H
Limusanno
Sukunya
S
Tantawichien
Terapong
T
Saikasem
Apinya
A
Raksakate
Somsri
S
D004355:Drug Stability; D004356:Drug Storage; D017048:Health Care Costs; D006801:Humans; D007117:Immunization, Secondary; D011819:Rabies Vaccines / Q000008:administration & dosage* / Q000378:metabolism; D013696:Temperature; D014944:World Health Organization
D011819:Rabies Vaccines