[Clinical and experimental study on the treatment of myelodysplastic syndromes with fuzheng quxie tablet].
OBJECTIVE
To study the mechanism of Fuzheng Quxie Tablet (FZQXT) in treating myelodysplastic syndromes (MDS).


METHODS
Thirty-three cases of MDS were treated with FZQXT, changes of peripheral blood cells, morphology of bone marrow smear, bone marrow pathology and immunology were monitored before and after treatment. The effects of FZQXT on hematopoietic stem cells of mice were also observed.


RESULTS
The remission rate and total effective rate were 24.24% and 72.72% respectively. FZQXT had obvious effect in promoting the proliferation of colony forming unit-erythrocytes (CFU-E).


CONCLUSIONS
The beneficial effect of FZQXT in treating refractory anemia might be reached through promoting the proliferation of erythrocytic hematopoietic stem cells.
Wang
Z
Z
Department of Hematology, Xiyuan Hospital, China Academy of TCM, Beijing (100091).
Ma
R
R
Zheng
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002455:Cell Division; D002648:Child; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D015672:Erythroid Precursor Cells / Q000166:cytology; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000188:drug therapy*
D004365:Drugs, Chinese Herbal