title: Angiogenic factors and bladder cancer.
abstract: Angiogenesis is required for the growth as well as expansion of a solid tumor. It has been reported that tumor angiogenesis may be triggered after an increase in the level of angiogenic factors and a concomitant decrease in the level of angiogenic inhibitors. Of all potential pro-angiogenic mediators of bladder cancer, VEGF and bFGF appear to be most relevant in terms of physiology. To date, it appears that the angiogenic factors and inhibitors may play an important role in the diagnosis and prognosis of bladder cancer.
authors.affiliation: Department of Surgery, Cancer Hospital/Cancer Institute, Fu Dan University, Shanghai, 200032, P. R. China.
authors.forename: Zhi-Ming
authors.initials: ZM
authors.lastname: Shao
authors.forename: Mai
authors.initials: M
authors.lastname: Nguyen
mesh_terms: D043925:Angiogenesis Inducing Agents / Q000502:physiology*; D000818:Animals; D006801:Humans; D009389:Neovascularization, Pathologic / Q000209:etiology* / Q000378:metabolism*; D001749:Urinary Bladder Neoplasms / Q000378:metabolism* / Q000473:pathology* / Q000503:physiopathology
chemical_list: D043925:Angiogenesis Inducing Agents