[Effects of human immunodeficiency virus infection on pregnancy outcome].
OBJECTIVE
To investigate the effects of human immunodeficiency virus (HIV) infection on the pregnancy outcome and the incidence of vertical transmission in HIV-positive pregnant women.


METHODS
86 cases of HIV-positive pregnant women and their infants were evaluated retrospectively, and HIV antibody in peripheral blood was detected using enzyme linked immunosorbent assay (ELISA).


RESULTS
Compared with normal control group, the incidences of abortion, preterm birth, low birth weight and small for gestational age babies were 9.3%, 14.0%, 16.3% and 10.5%, respectively (P < 0.05); the occurrence of conditional infections of reproductive tract was also higher (P < 0.05); and the incidence of vertical transmission was 12.8% (P < 0.01).


CONCLUSIONS
HIV infection in pregnant women markedly increases the risks of abortion, preterm birth, low birth weight and small for gestational age babies, and elevates the incidence of conditional infections of reproductive tract. The incidence of vertical transmission was 12.8%. These data support that it is very important to provide prenatal care to HIV-infected pregnant women and prevent pregnant women from HIV infection.
Dong
J
J
Department of Obstetrics and Gynecology, Second Hospital of Shandong University, Jinan 250033, China.
Ma
Y
Y
Ma
Y
Y
D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000635:transmission*; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D018445:Infectious Disease Transmission, Vertical; D007752:Obstetric Labor, Premature / Q000209:etiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious