title: [Craniofacial resection for advanced malignant tumors in oral and maxillofacial region].
abstract: OBJECTIVE
  To investigate the clinical significance of craniofacial resection for advanced malignant tumors of OMS region.
  
  
  METHODS
  Forty-six patients underwent craniofacial resection for malignancies involving the anterior and middle cranial fossa over a 20-year period between June 1978 and December 1997 in our department were evaluated. The extents of cranial resections were anterior cranial fossa in 20 cases, middle crania fossa in 16 cases and anterior and middle skull base in 10 cases. There were 18 patients undergoing orbital exenteration simultaneously. 14 cases had limitted dura resected because of dural involvement.
  
  
  RESULTS
  The survival rate at 3 and 5 years was 48.8% (20/41) and 35.1% (13/37), respectively. The survival rate at 10 years was 20.0% (4/20).
  
  
  CONCLUSIONS
  Our results revealed a considerably fine prospect of craniofacial resection for patients with advanced malignancies in oral and maxillofacial region.
authors.affiliation: School of Stomatology, Shanghai Second Medical University, Shanghai 200011.
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
authors.forename: W
authors.initials: W
authors.lastname: Qiu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000401:mortality / Q000601:surgery*; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000401:mortality / Q000601:surgery*; D012888:Skull Neoplasms / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome