[Familial occurrence of hearing loss following streptomycin (SM) treatment].
References data indicate the probability of inheritance of predisposition to post-streptomycin hearing loss. Ototoxicity after SM is transmitted by women. It is considered as autosomal dominant inheritance, but the transmission to the next generation is not explained by the Mendelian inheritance rule. The aim of our presentation is showing different kinds of hearing loss after SM occurring in siblings with probable inherited susceptibility to SM.
Niedzielska
G
G
Klinika Otolaryngologii Dzieciecej, Foniatrii i Audiologii Akademii Medycznej w Lublinie.
Katska
E
E
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003638:Deafness / Q000139:chemically induced* / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D008875:Middle Aged; D013307:Streptomycin / Q000009:adverse effects* / Q000627:therapeutic use; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D013307:Streptomycin
Rodzinne wystepowanie niedosłuchu odbiorczego zwiazanego z leczeniem streptomycyna.