[The influence of resuscitation with solutions containing different concentrations of sodium on the homeostasis of burn patients during the early postburn stage].
OBJECTIVE
To investigate the influence of resuscitation with solutions containing different concentrations of sodium on the homeostasis of burn patients during the early postburn stage.


METHODS
Thirty-five cases of burn patients inflicted with 50% approximately 100% of TBSA including 20% approximately 88% of 3rd degree burn were enrolled in the study. All the patients studied were divided into A[(Na+) = 174 mmol/L] and B [(Na+) = 130 mmol/L] groups according to different concentrations of sodium in the infusion solution. The input of the fluid, plasma crystal osmotic pressure, plasma ratio of albumin to globulin, urine output and pH value and anasarcous degree were observed during 1 to 5 postburn days (PBDs).


RESULTS
The infusion fluid amount per hour in A group was 20 approximately 30 ml less than that in B group within 3 PBDs. The infused sodium amount in A group was more than that in B group within 5 PBDs. The FENa in A group was in normal range within 5 PBDs, while that in B group was lower than normal. This might be related to different infusion amounts of water and sodium.


CONCLUSIONS
The homeostasis of burn patients could be significantly affected by the water load and the sodium concentration in the resuscitation solution during early postburn stage.
Zhu
S
S
Department of Burns, Changhai Hospital, Second Military Medical University, Shanghai 200433, P. R. China.
Huo
Z
Z
Ge
S
S
D000328:Adult; D002056:Burns / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology; D002712:Chlorides / Q000097:blood; D004305:Dose-Response Relationship, Drug; D005260:Female; D006706:Homeostasis / Q000187:drug effects*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D015532:Rehydration Solutions / Q000494:pharmacology* / Q000627:therapeutic use; D012964:Sodium / Q000097:blood / Q000494:pharmacology* / Q000627:therapeutic use; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome; D014554:Urination / Q000187:drug effects; D014556:Urine
D002712:Chlorides; D015532:Rehydration Solutions; D012964:Sodium; D011188:Potassium