title: Synthesis and evaluation of new triazolobenzothiazole derivatives as potential anti-tubercular agents.
abstract: A series of sulfonamides and S-benzyl derivatives of substituted/unsubstituted S-triazolo-(3,4,-b)-benzothiazole-3-thiones were synthesized. These triazolobenzolobenzothiazole derivatives were evaluated for antitubercular activity against H37Rv strain of Mycobacterium tuberculosis. A number of promising compounds have been obtained.
authors.affiliation: Department of Chemotherapy, Haffkine Institute, Mumbai, India.
authors.forename: S D
authors.initials: SD
authors.lastname: Paranjape
authors.forename: A S
authors.initials: AS
authors.lastname: Bobade
authors.forename: B G
authors.initials: BG
authors.lastname: Khadse
mesh_terms: D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D000995:Antitubercular Agents; D013844:Thiazoles; D014230:Triazoles