title: Myoclonus secondary to withdrawal from transdermal fentanyl: case report and literature review.
abstract: Myoclonus is a common and well-described adverse effect of opioids. Most cases reported in the literature have been associated with opioid administration, rather than with opioid withdrawal. We describe a case of myoclonus secondary to withdrawal from transdermal fentanyl. We review the literature regarding myoclonus related to opioid therapy (opioid-induced myoclonus) and withdrawal (opioid withdrawal myoclonus), and discuss possible mechanisms and therapies for these phenomena.
authors.affiliation: Section of Palliative Care and Medical Ethics Division of General Internal Medicine, University of Pittsburgh Medical Center, 5320 Centre Avenue, Pittsburgh, PA 15232, USA.
authors.forename: Paul K J
authors.initials: PK
authors.lastname: Han
authors.forename: Robert
authors.initials: R
authors.lastname: Arnold
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Bond
authors.forename: Douglas
authors.initials: D
authors.lastname: Janson
authors.forename: Kareem
authors.initials: K
authors.lastname: Abu-Elmagd
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D009207:Myoclonus / Q000139:chemically induced*; D013375:Substance Withdrawal Syndrome
chemical_list: D005283:Fentanyl