title: Influence of body size and age on maximal diastolic velocity of mitral annulus motion.
abstract: BACKGROUND
  Maximal long-axis relaxation velocity (RV(m)), measured from the mitral annulus motion (MAM), has recently been suggested as an index of left ventricular (LV) diastolic function. M-mode recording and pulsed tissue Doppler have been used. Regarding the M-mode method, reference values have not been presented previously. In the current study, therefore, the influence on RV(m) of such variables as age, body size, heart rate, and blood pressure was investigated to obtain adequate reference values.
  
  
  RESULTS
  Fifty-seven healthy subjects were included in the study. RV(m) was recorded by M-mode echocardiography from apical 4- and 2-chamber views from 4 sites of the mitral annulus. Multiple regression analysis showed that heart rate ought to be taken into account when reference values are calculated for children and adolescents, and age must be considered in adults. For reference values in children and adolescents, the following equation is suggested: RV(m) = 171 - 0.54 x heart rate (SEE = 18.7). In adults over 18 years, the suggested equation is RV(m) = 163 - 1.29 x age (SEE = 8.4.)
authors.affiliation: Department of Anesthesiology, Central Hospital, Karlstad, Sweden. bo.nilsson@liv.se
authors.forename: Bo
authors.initials: B
authors.lastname: Nilsson
authors.forename: Leif
authors.initials: L
authors.lastname: Bojö
authors.forename: Birger
authors.initials: B
authors.lastname: Wandt
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D001824:Body Constitution / Q000502:physiology*; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D003971:Diastole / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000502:physiology*; D012016:Reference Values; D012119:Respiration; D013318:Stroke Volume / Q000502:physiology; D014463:Ultrasonography