[Relationship between maternal nutritional stetus and intrauterine growth retardation with neonatal visual development disorder].
OBJECTIVE
To investigate the relationship between the maternal nutritional stetus and the occurrence of intrauterine growth retardation (IUGR) with neonatal visual development disorder.


METHODS
Sixty pregnant women closed to expected date of confinement were randomly divided into 2 groups: IUGR and normal control group, each were with 30 cases. Eight kinds of nutritional foods taken by the pregnant women were investigated and scored. The vitamin A concentrations of maternal and umbilical blood were measured with fluorometer method. The concentrations of iron, copper and zinc in maternal and umbilical blood were detected by spectrophotometer. The results of examination with Flash-visual evoked potentials (F-VEP) were recorded by an experienced technician in neonates at 3-7 days after birth and 10 months after follow-up.


RESULTS
Compared with the normal control, the IUGR group had taken less eggs, animal liver and fat pork during pregnancy (P < 0.05), had remarkable lower concentrations of vitamin A and iron in maternal and umbilical blood (P < 0.01), and had a lower umbilical blood zinc concentration (P < 0.05). Meanwhile, neonates with IUGR had obvious delay of the latent period of F-VEP's main positive component (P100) (P < 0.05) and an attenuation of the P100 with when it was measured at 3-7 days after birth and at 10th month after fellow-up (P < 0.01).


CONCLUSIONS
The decreased intake of foods rich in vitamin A, iron, zinc and other nutritional components was closely correlated with IUGR occurrence and resulted in retardation of neonate visal development.
Ying
X
X
Department of Obstetrics and Gynecology, Second Affiliated Hospital, Nanjing Medical University, Nanjing 210011, China.
Chen
Y
Y
Le
H
H
D005074:Evoked Potentials, Visual; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology*; D006801:Humans; D009752:Nutritional Status; D011247:Pregnancy; D011897:Random Allocation; D014786:Vision Disorders / Q000209:etiology*