[The expression of TGF-beta receptors on cultured human dental papilla cells].
OBJECTIVE
To observe the expression of TGF-beta receptors on cultured human dental papilla cells and the effects of TGF-beta on TGF-beta receptors of the cells.


METHODS
The expression of TGF-beta receptors on cultured human dental papilla cells and the effects of TGF-beta on TGF-beta receptors of the cells were examined by cell culture and immunohistochemical technique and image analysis.


RESULTS
Type I, type II receptors for TGF-beta in human dental papilla cells were stained strongly and type III was weakly positive. Image analysis indicated that all experimental groups had no obvious difference with control groups (P > 0.05).


CONCLUSIONS
Cultured human dental papilla cells express TGF-beta type I, type II and type III receptors. TGF-beta has no obvious effects on the cell receptor expression.
Zhang
Y
Y
Department of Oral Medicine, School of Stomatology, Fourth Military Medical University, Xi'an 710032, China.
Zhang
Y
Y
Shi
J
J
D030201:Activin Receptors, Type I / Q000096:biosynthesis; D002478:Cells, Cultured; D003771:Dental Papilla / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D017346:Protein Serine-Threonine Kinases; D011509:Proteoglycans / Q000096:biosynthesis; D000077293:Receptor, Transforming Growth Factor-beta Type I; D000077294:Receptor, Transforming Growth Factor-beta Type II; D018125:Receptors, Transforming Growth Factor beta / Q000096:biosynthesis* / Q000145:classification; D016212:Transforming Growth Factor beta / Q000494:pharmacology
D011509:Proteoglycans; D018125:Receptors, Transforming Growth Factor beta; D016212:Transforming Growth Factor beta; C071736:betaglycan; D017346:Protein Serine-Threonine Kinases; D030201:Activin Receptors, Type I; D000077293:Receptor, Transforming Growth Factor-beta Type I; D000077294:Receptor, Transforming Growth Factor-beta Type II