Apoptosis-inducing cleavage of caspases by trimidox, an inhibitor of ribonucleotide reductase.
Fritzer-Szekeres
M
M
Clin. Institute for Med. & Chem. Laboratory Diagnostics, Medical School, University of Vienna, Austria.
Luxbacher
C
C
Horvath
Z
Z
Grusch
M
M
Krupitza
G
G
Elford
H L
HL
Szekeres
T
T
D017209:Apoptosis; D001550:Benzamidines / Q000494:pharmacology*; D053148:Caspase 3; D061945:Caspase Inhibitors; D053938:DNA Fragmentation; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D015870:Gene Expression / Q000187:drug effects; D018922:HL-60 Cells; D006801:Humans; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics; D012264:Ribonucleotide Reductases / Q000037:antagonists & inhibitors*
C074761:3,4,5-trihydroxybenzamidoxime; D001550:Benzamidines; D061945:Caspase Inhibitors; D004791:Enzyme Inhibitors; D016271:Proto-Oncogene Proteins c-myc; D012264:Ribonucleotide Reductases; D011065:Poly(ADP-ribose) Polymerases; C505407:CASP3 protein, human; D053148:Caspase 3