title: beta-Thromboglobulin in patients with acute myocardial infarction according to the treatment.
abstract: Many studies report on the increased activity of platelets in patients with heart disease, especially with acute myocardial infarction (MI). The aim of the present study was to evaluate dynamics of beta-thromboglobulin (beta-TG) concentration in patients with MI according to the disease duration and type of treatment. We investigated 29 patients, who were divided into two groups according to the type of treatment. beta-TG concentration was determined using the immunoenzymatic method (ELISA). Blood was taken 1st, 3rd, 5th, 8th and 11th day of infarction. Our results indicate that in the course of myocardial infarction there is a change in platelet activation. The treatment applied affects beta-TG concentration, and the thrombolytic therapy inhibits platelet activation.
authors.affiliation: Department of Clinical Laboratory Diagnostics, Medical Academy of Białystok, Białystok, Poland.
authors.forename: V
authors.initials: V
authors.lastname: Dymicka-Piekarska
authors.forename: H
authors.initials: H
authors.lastname: Kemona
authors.forename: M
authors.initials: M
authors.lastname: Mantur
authors.forename: A
authors.initials: A
authors.lastname: Stogowski
authors.forename: I
authors.initials: I
authors.lastname: Kemona-Chetnik
mesh_terms: D001241:Aspirin / Q000008:administration & dosage; D016022:Case-Control Studies; D005260:Female; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000188:drug therapy; D015539:Platelet Activation / Q000187:drug effects; D013300:Streptokinase / Q000008:administration & dosage; D015912:Thrombolytic Therapy; D001620:beta-Thromboglobulin / Q000378:metabolism*
chemical_list: D001620:beta-Thromboglobulin; D006493:Heparin; D013300:Streptokinase; D001241:Aspirin