title: Recurrent arterial thrombosis in a child: primary antiphospholipid antibody syndrome.
abstract: Antiphospholipid antibody syndrome (APS) is characterized by the association of recurrent arterial or venous thrombosis or recurrent fetal wastage and the presence of circulating antiphospholipid antibodies, detected as anticardiolipin antibodies or lupus anticoagulant. The authors report an 8-year-old girl, who presented with central retinal artery occlusion and live do reticularis and was diagnosed as APS. Despite the proper anticoagulant treatment she had several cerebral ischemic events and died 29 months after the diagnosis. A larger number of pediatric case investigations will be required for better understanding and treating this rare thrombotic disorder.
authors.affiliation: Department of Pediatric Hematology, Ankara University, School of Medicine, Turkey.
authors.forename: Zümrüt
authors.initials: Z
authors.lastname: Uysal
authors.forename: Figen
authors.initials: F
authors.lastname: Doğu
authors.forename: A Emin
authors.initials: AE
authors.lastname: Kürekçi
authors.forename: Vildan Koşan
authors.initials: VK
authors.lastname: Culha
authors.forename: Gülhis
authors.initials: G
authors.lastname: Deda
authors.forename: Mesiha
authors.initials: M
authors.lastname: Ekim
authors.forename: Nejat
authors.initials: N
authors.lastname: Akar
authors.forename: Mehmet
authors.initials: M
authors.lastname: Erterm
authors.forename: Aydan
authors.initials: A
authors.lastname: Ikincioğullari
authors.forename: Emel
authors.initials: E
authors.lastname: Babacan
authors.forename: Sevgi
authors.initials: S
authors.lastname: Gözdaşoğlu
mesh_terms: D017153:Antibodies, Anticardiolipin / Q000097:blood; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D002648:Child; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D012008:Recurrence; D015356:Retinal Artery Occlusion / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D017445:Skin Diseases, Vascular / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000473:pathology
chemical_list: D017153:Antibodies, Anticardiolipin