title: Ileal pouch-anal anastomosis for ulcerative colitis: the University of Puerto Rico experience.
abstract: OBJECTIVE
  To review the experience with ileal pouch-anal anastomosis surgery for ulcerative colitis at the University Hospital.
  
  
  BACKGROUND
  As many as 40% of patients with ulcerative colitis (UC) and 75% with Crohn's disease (CD) require some surgery for their disease. The number of patients referred to our clinics for evaluation and management of Inflammatory Bowel Disease (IBD) has risen in the past seven years. A multidisciplinary IBD service has been created at the University Hospital for the care of these patients, leading to a dramatic increase in the number of surgeries performed for IBD. Over the past decade the ileal pouch-anal anastomosis (IPAA) has emerged as the procedure of choice in most patients with ulcerative colitis requiring total colectomy for management of their disease. Even though the procedure is associated with a considerable morbidity rate, it has become very popular since it avoids the need for a permanent stoma and presumably rids the patient of disease and subsequent cancer risk.
  
  
  RESULTS
  Twenty-five patients were identified as having IPAA for ulcerative colitis between 1993-2000. Indications for surgery were intractability and toxic megacolon. Complications were pouchitis in 11/25 (44%), anastomotic stricture in 6/25 (24%), small bowel obstruction in 4/25 (16%), and pouch failure in 2/25 (8%). Other complications included wound abscess in 1/25 (4%), and sexual dysfunction in 1/25 (4%) patients. There was no mortality; the patients' quality of life was rated as greatly improved in 14 of 17 patients interviewed (82.4%) and 16 of 17 said they would recommend the surgery to others (94.1%).
  
  
  CONCLUSIONS
  The results of IPAA surgery, morbidity, mortality, and patient satisfaction in our series were similar to other centers around the world.
authors.affiliation: Inflammatory Bowel Disease Service, Department of Medicine, University of Puerto Rico School of Medicine, Medical Sciences Campus.
authors.forename: R
authors.initials: R
authors.lastname: Vendrell
authors.forename: M
authors.initials: M
authors.lastname: Iñesta
authors.forename: R
authors.initials: R
authors.lastname: Mera
authors.forename: J
authors.initials: J
authors.lastname: Iturrino
authors.forename: A
authors.initials: A
authors.lastname: Soto
authors.forename: M
authors.initials: M
authors.lastname: Mas
authors.forename: J J
authors.initials: JJ
authors.lastname: Lojo
authors.forename: E A
authors.initials: EA
authors.lastname: Torres
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011183:Postoperative Complications; D019449:Pouchitis / Q000209:etiology; D016737:Proctocolectomy, Restorative; D011647:Puerto Rico; D011788:Quality of Life