title: The first atisane diterpenoids from a liverwort: polyols from Lepidolaena clavigera.
abstract: Two new diterpenoids were isolated from the New Zealand liverwort Lepidolaena clavigera. Spectroscopic studies identified the structures as atisanes 1 and 2, with an unprecedented level of oxygenation. This is the first report of the atisane skeleton from a liverwort. Compound 2 showed cytotoxic and insecticidal activity. [structure: see text]
authors.affiliation: Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd., Department of Chemistry, University of Otago, Box 56, Dunedin, New Zealand. perryn@crop.cri.nz
authors.forename: N B
authors.initials: NB
authors.lastname: Perry
authors.forename: E J
authors.initials: EJ
authors.lastname: Burgess
authors.forename: S H
authors.initials: SH
authors.lastname: Baek
authors.forename: R T
authors.initials: RT
authors.lastname: Weavers
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013058:Mass Spectrometry; D008958:Models, Molecular; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D007306:Insecticides