Difficulties in diagnosis and treatment of ectopic ACTH-producing tumors of the chest.
It is widely accepted that surgery is the first choice treatment for ACTH-secreting tumors, most of them being lung or bronchial tumors. However, the localization of such lesions is rather difficult and it needs a compelling work-up. Here we present the results of different hormonal and imaging investigations and the surgical outcome of three patients with ectopic Cushing's syndrome.
Dall'Asta
Chiara
C
Institute of Endocrine Sciences, University of Milan, Ospedale Maggiore IRCCS - pad. Granelli Via F. Sforza 35, 20122 Milan, Italy.
Santambrogio
Luigi
L
Castellani
Massimo
M
Ambrosi
Bruno
B
D000182:ACTH Syndrome, Ectopic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery*; D000328:Adult; D001984:Bronchial Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism*; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging