[Laboratory-based surveillance of salmonellosis of humans in Germany--safety of Salmonella typhimurium and Salmonella enteritidis live vaccines].
The Paul Ehrlich Institute, Langen, in Germany has been licensed different live vaccines of S. Typhimurium and S. Enteritidis for use in the veterinary medicine since I the 90s. The Robert Koch Institute has established a lab-based surveillance system for these live vaccine strains for an evaluation of recent public health safety. Since 2000 all strains of S. Typhimurium and S. Enteritidis from humans were investigated in respect to their phage types and other vaccine markers. 3676 S. Typhimurium strains and 4489 S. Enteritidis strains mainly from Salmonellose patients were investigated after phage typing according to their auxotrophic or antibiotic resistance markers. The live vaccine strains of Zoosaloral, TAD Salmonella vacT or TAD Salmonella vacE and Salmovac SE could not be found from infections in humans.
Rabsch
W
W
Robert-Koch-Institut, Bereich Wernigerode. rabschw@rki.de
Liesegang
A
A
Tschäpe
H
H
D000818:Animals; D001434:Bacteriophage Typing / Q000662:veterinary; D006801:Humans; D011634:Public Health; D012449:Safety; D012480:Salmonella Infections / Q000382:microbiology / Q000517:prevention & control*; D022562:Salmonella Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D012477:Salmonella enteritidis / Q000145:classification / Q000276:immunology*; D012486:Salmonella typhimurium / Q000145:classification / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000009:adverse effects
D022562:Salmonella Vaccines; D014613:Vaccines, Attenuated
Laborgestützte Uberwachung der Salmonellose des Menschen in Deutschland--Beitrag zur Sicherheit von Salmonella Typhimurium- und Salmonella Enteritidis-Lebendimpfstoffen.