title: Cell inactivation by beryllium, boron and carbon ions at the low-energy irradiation facility of the Naples University.
abstract: The 3MV HVEC TTT-3 Tandem accelerator at the University of Naples, already used for radiobiological studies with protons and alpha particles, was set up for irradiation of biological samples with low energy carbon, boron, and beryllium beams. Radiobiological characterisation and study of these ion beams is essential in hadrontherapy (correction of hadrotherapy) to understand, for example, the possible biological effect of the target fragmentation products. Furthermore in space radiation biology we need to know the biological effects of heavy ions, a component of cosmic radiation that can contribute to the radiobiological risk when long sojourns in space are concerned. V79 Chinese hamster cells were irradiated with the different ions and the resulting cell inactivation data are reported.
authors.affiliation: Servizio di Radioprotezione, Universita di Napoli "Federico II" Complesso universitario di Monte S. Angelo, Napoli, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Scampoli
authors.forename: M
authors.initials: M
authors.lastname: Casale
authors.forename: M
authors.initials: M
authors.lastname: Durante
authors.forename: G
authors.initials: G
authors.lastname: Grossi
authors.forename: M
authors.initials: M
authors.lastname: Pugliese
authors.forename: G
authors.initials: G
authors.lastname: Gialanella
mesh_terms: D000818:Animals; D001608:Beryllium; D001895:Boron; D002244:Carbon; D002470:Cell Survival / Q000528:radiation effects*; D002478:Cells, Cultured / Q000528:radiation effects; D006224:Cricetinae; D003412:Cricetulus; D004307:Dose-Response Relationship, Radiation; D020450:Heavy Ions; D010315:Particle Accelerators; D012062:Relative Biological Effectiveness
chemical_list: D002244:Carbon; D001895:Boron; D001608:Beryllium