title: Safety considerations for in vitro toxicology testing.
abstract: A range of hazards may be encountered in in vitro toxicology laboratory work. Such hazards are primarily chemical reagents for which the level of risk, particularly with long-term exposure, may be difficult to ascertain. Cells and tissues may also present biosafety concerns and it is important that risk assessments are prepared for each procedure before commencing project work. Ideally control measures should be simple and combine the use of appropriate equipment with documented procedures supported by risk assessments. In any laboratory staff and procedures change significantly over time, thus monitoring of procedures (including waste disposal) and a comprehensive training programme for all staff are essential components to assure both the quality and safety of laboratory work.
authors.affiliation: National Institute of Biological Standards and Control, Potters Bar, UK.
authors.forename: B
authors.initials: B
authors.lastname: Jones
authors.forename: G
authors.initials: G
authors.lastname: Stacey
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques / Q000592:standards*; D019411:Clinical Laboratory Techniques / Q000295:instrumentation; D015386:Hazardous Substances / Q000633:toxicity; D006801:Humans; D017744:Medical Waste Disposal; D018570:Risk Assessment; D012449:Safety; D018675:Toxicity Tests / Q000592:standards; D014780:Viruses
chemical_list: D015386:Hazardous Substances; D017744:Medical Waste Disposal