[Expression of stress-evoked analgesia, connected with activity of animals in a forced swimming test].
The influence of forced swimming on the development of stress-induced analgesia was studied in 35 SHR mice, 65 NMRI mice, and 23 white outbred male rats. Mice were subjected to swimming conditions (at a temperature of 11 degrees C) for a period of 4 minutes and rats for 6 minutes. Pain thresholds were measured by a footshock. It was shown that behavioral response to acute stress is associated with a change in the pain tolerance threshold: activity of an animal under test conditions positively correlated with stress-induced analgesia. The response to stress and parameters of stress-induced analgesia depend on the genetic factor and age, however, the correlation between the activity during exposure to stress and the extent of stress-induced analgesia conserves in all cases.
Kenunen
O G
OG
Bekhterev Psychoneurological Research Institute, St.-Petersburg.
Prakh'e
I V
IV
Kozlovskié
V L
VL
D000698:Analgesia; D000818:Animals; D008297:Male; D051379:Mice; D010146:Pain; D012684:Sensory Thresholds; D013312:Stress, Physiological / Q000503:physiopathology*; D013550:Swimming
Vyrazhennost' analgezii, vyzvannoé stressom, sviazana s aktivnost'iu zhivotnykh v teste neizbegaemogo plavaniia.