title: Apoptosis-inducing cleavage of caspases by trimidox, an inhibitor of ribonucleotide reductase.
authors.affiliation: Clin. Institute for Med. & Chem. Laboratory Diagnostics, Medical School, University of Vienna, Austria.
authors.forename: M
authors.initials: M
authors.lastname: Fritzer-Szekeres
authors.forename: C
authors.initials: C
authors.lastname: Luxbacher
authors.forename: Z
authors.initials: Z
authors.lastname: Horvath
authors.forename: M
authors.initials: M
authors.lastname: Grusch
authors.forename: G
authors.initials: G
authors.lastname: Krupitza
authors.forename: H L
authors.initials: HL
authors.lastname: Elford
authors.forename: T
authors.initials: T
authors.lastname: Szekeres
mesh_terms: D017209:Apoptosis; D001550:Benzamidines / Q000494:pharmacology*; D053148:Caspase 3; D061945:Caspase Inhibitors; D053938:DNA Fragmentation; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D015870:Gene Expression / Q000187:drug effects; D018922:HL-60 Cells; D006801:Humans; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics; D012264:Ribonucleotide Reductases / Q000037:antagonists & inhibitors*
chemical_list: C074761:3,4,5-trihydroxybenzamidoxime; D001550:Benzamidines; D061945:Caspase Inhibitors; D004791:Enzyme Inhibitors; D016271:Proto-Oncogene Proteins c-myc; D012264:Ribonucleotide Reductases; D011065:Poly(ADP-ribose) Polymerases; C505407:CASP3 protein, human; D053148:Caspase 3