[Expression of leukemia inhibitory factor in human decidua].
OBJECTIVE
To study the expression and localization of leukemia inhibitory factor (LIF) in human first trimester decidual.


METHODS
By immunohistochemical analysis and in situ hybridization, the LIF mRNA and protein expression were observed in 16 cases of human decidua.


RESULTS
LIF mRNA and protein expressions were observed in all decidual specimens, the glanduar epithelium showed higher LIF expression than in stromal cells.


CONCLUSIONS
Expression of LIF in human decidua may contribute to embryo implantation, maintenance of placental functions and embryonic growth promation.
Wang
L
L
Department of Obstetrics and Gynecology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Shi
C
C
Yu
C
C
D000328:Adult; D003656:Decidua / Q000737:chemistry*; D010064:Embryo Implantation; D005314:Embryonic and Fetal Development; D005260:Female; D006131:Growth Inhibitors / Q000032:analysis* / Q000235:genetics / Q000502:physiology; D006801:Humans; D015850:Interleukin-6; D053605:Leukemia Inhibitory Factor; D008222:Lymphokines / Q000032:analysis* / Q000235:genetics / Q000502:physiology; D011247:Pregnancy; D012333:RNA, Messenger / Q000032:analysis
D006131:Growth Inhibitors; D015850:Interleukin-6; C507837:LIF protein, human; D053605:Leukemia Inhibitory Factor; D008222:Lymphokines; D012333:RNA, Messenger