[The effect of a nonprotein spleen factor on the course of delayed-type hypersensitivity and graft versus host reactions].
The effects of splenoside on the reactions of delayed-type hypersensitivity and graft versus host were investigated. Even single splenoside injection (50 mg/10 g b.w.) increased graft versus host reaction in newborn mice-hybrids F1. Splenoside influences the delayed-type hypersensitivity reaction in dose-depending manner: the dose of 50 mg/10 g increases the reaction and 100 mg/10 g decreases it.
Bykova
L M
LM
V.P. Komisarenko Institute of Endocrinology and Metabolism, Kiev.
Synel'nykova
H L
HL
Oliĭnyk
B V
BV
D000818:Animals; D001685:Biological Factors / Q000008:administration & dosage / Q000494:pharmacology*; D004306:Dose-Response Relationship, Immunologic; D006087:Graft vs Host Reaction / Q000187:drug effects* / Q000276:immunology*; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D009705:Nucleosides / Q000008:administration & dosage / Q000494:pharmacology*; D013154:Spleen / Q000276:immunology / Q000502:physiology
D001685:Biological Factors; D009705:Nucleosides
Perebih reaktsiï hiperchutlyvosti upovil'nenoho typu ta "transplantat proty khaziaïna" pid vplyvom nebilkovoho chynnyka selezinky.