What does the presence of hypertension portend in the Nigerian with non insulin dependent diabetes mellitus.
132 Nigerians with Non Insulin -dependent diabetes mellitus (NIDDM) were divided into two groups (NIDDM) patients with hypertension and those without) and their clinico-laboratory parameters were studied and analyzed. Their mean age (SD) was 59.5+/-9 years. Body mass index (BMI) was 25.2+/-3.5 kg/m2 and the duration of DM was 6.9+/-6 years. The prevalence of hypertension was 55(41.6%) No significant difference were observed in the age, sex ratio and BMI of both groups but the duration of DM showed a statistical difference between the two groups. However, laboratory parameters such as fasting blood glucose, serum urea, creatinine clearance and degree of proteinuria all showed statistically significant difference between the hypertensive and normotensive groups. Also the hypertensive diabetic group were observed to have more end organ damage i.e peripheral neuropathy, diabetic retinopathy and diabetic nephropathy than the normotensive diabetics. We conclude that, hypertension in NIDDM patients has prognostic implications and so more aggressive efforts be made in detecting and controlling hypertension in DM patients.
Ikem
R T
RT
Department of Medicine, College of Health Sciences, Obafemi Awolowo University Ile-Ife.
Akinola
N O
NO
Balogun
M O
MO
Ohwovoriole
A E
AE
Akinsola
A
A
D017677:Age Distribution; D000368:Aged; D044383:Black People; D001786:Blood Glucose / Q000032:analysis; D001806:Blood Urea Nitrogen; D015992:Body Mass Index; D016022:Case-Control Studies; D003404:Creatinine / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism; D003929:Diabetic Neuropathies / Q000145:classification / Q000209:etiology; D003930:Diabetic Retinopathy / Q000145:classification / Q000209:etiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000378:metabolism / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D015995:Prevalence; D011379:Prognosis; D011507:Proteinuria / Q000209:etiology; D012720:Severity of Illness Index; D017678:Sex Distribution
D001786:Blood Glucose; D003404:Creatinine