title: Diverting loop colostomy for the treatment of refractory gastrointestinal bleeding secondary to radiation proctitis.
abstract: Chronic radiation proctitis is an uncommon and serious complication of radiotherapy for pelvic malignancies. It has been suggested that fecal stream diversion decreases bowel irritation, resulting in decreased rectal bleeding. We report on the outcome of patients after a diverting loop colostomy for the treatment of severe radiation proctitis. All consecutive patients with chronic proctitis treated with diverting loop colostomy for bleeding at one institution between October 1991 and June 1999 were studied. Four patients presented with rectal bleeding and diarrhea, and two patients had only bleeding. The mean dose of radiation received was 6,115.11 +/- 955.11 rad. Symptoms of chronic proctitis appeared at varying intervals of time after radiation, ranging from 14 months to 17 years. There were no operative complications. During follow-up (36 +/- 29 months), only one of nine patient continued to bleed. Four patients died during the study (cancer relapse, two patients; heart failure, one patient; one death was caused by severe radiation proctitis). Diverting sigmoid loop colostomy, when performed in properly selected patients with severe bleeding secondary to radiation proctitis refractory to medical management, is well tolerated and effective.
authors.affiliation: Department of General Surgery, Guthrie Clinic/Robert Packer Hospital, One Guthrie Square, Sayre, PA 18840, USA.
authors.forename: J
authors.initials: J
authors.lastname: Ayerdi
authors.forename: K
authors.initials: K
authors.lastname: Moinuddeen
authors.forename: A
authors.initials: A
authors.lastname: Loving
authors.forename: J
authors.initials: J
authors.lastname: Wiseman
authors.forename: N
authors.initials: N
authors.lastname: Deshmukh
mesh_terms: D000368:Aged; D003125:Colostomy / Q000379:methods*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011349:Proctitis / Q000150:complications*; D011832:Radiation Injuries / Q000150:complications*; D012189:Retrospective Studies