Nickel-catalyzed highly regio- and chemoselective cocyclotrimerization of propiolates with allenes: a novel route to polysubstituted benzene derivatives.
The Ni(dppe)Br(2)/Zn system effectively catalyzes the cocyclotrimerization of propiolates with allenes. The reaction is highly regio- and chemoselective to afford polysubstituted benzene derivatives in good to excellent yields. [reaction: see text]
Shanmugasundaram
M
M
Department of Chemistry, Tsing Hua University, Hsinchu, Taiwan 300.
Wu
M S
MS
Cheng
C H
CH