title: A low stiffness composite biologically fixed prosthesis.
abstract: The current authors addressed the question whether stress-induced adaptive bone remodeling of the proximal femur is a necessary consequence after total hip reconstruction with extensively biologically-fixed femoral components. A novel total hip femoral component was designed to simultaneously achieve stable skeletal fixation, structural durability, and reduced femoral stress shielding. This implant allowed for proximal and distal canal filling, yet was significantly less rigid than all-metallic femoral stems crafted of either cobalt chromium or titanium alloy. A cohort of 366 patients (386 hips) treated at 21 institutions worldwide now have been followed up a mean of 2.4 years postoperatively (range, 3 months-6 years). Two hundred sixty-eight patients have 2 years minimum followup. To date, no femoral implants have failed to achieve bone ingrowth and none have required revision. The implants appear radiographically well-fixed with no progressive radiolucencies or osteolysis. Radiostereometric analysis studies on one subset of patients showed stable initial fixation and minimal stem micromotion. Dual energy xray absorptiometry analysis on another subset of patients revealed excellent periprosthetic bone mineral density retention. Compared with more rigid metal implants, this design shows reduced proximal femoral bone loss secondary to stress-mediated bone resorption.
authors.affiliation: The Anderson Orthopaedic Clinic, Arlington, VA, USA.
authors.forename: A H
authors.initials: AH
authors.lastname: Glassman
authors.forename: R D
authors.initials: RD
authors.lastname: Crowninshield
authors.forename: R
authors.initials: R
authors.lastname: Schenck
authors.forename: P
authors.initials: P
authors.lastname: Herberts
mesh_terms: D015502:Absorptiometry, Photon; D015519:Bone Density; D001862:Bone Resorption; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000517:prevention & control; D011446:Prospective Studies; D011474:Prosthesis Design