title: [Telomerase activity in stool of patients with colorectal cancer].
abstract: OBJECTIVE
  To probe into the method for screening colorectal cancer by the way of stool.
  
  
  METHODS
  Telomerase activity in the stool of patients with colorectal cancer was determined by PCR-TRAP.
  
  
  RESULTS
  The positive rate of telomerase activity in the stool of patients with colorectal cancer was 62.8%. Its sensitivity, specificity and positive predictive value were 62.8%, 95.7%, and 96.4%, respectively. Telomerase activity in stool was not obviously correlated with Duke's stage, lymphatic metastasis and tumor location. Telomerase activity was also found in the stool sample of a patient with colonic adenoma.
  
  
  CONCLUSIONS
  The determination of telomerase activity in the stool of patients with colorectal cancer contributes to the improvement of screening and diagnosis of colorectal cancer.
authors.affiliation: Department of General Surgery, Beijing Military Area General Hospital, Beijing 100700, China.
authors.forename: C
authors.initials: C
authors.lastname: Luo
authors.forename: D
authors.initials: D
authors.lastname: Zhao
authors.forename: J
authors.initials: J
authors.lastname: Qu
mesh_terms: D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000201:enzymology*; D005243:Feces / Q000737:chemistry*; D006801:Humans; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D019098:Telomerase / Q000378:metabolism*
chemical_list: D019098:Telomerase