title: [The molecular mechanism of aging and longevity and the function of Sir2 proteins].
authors.forename: S
authors.initials: S
authors.lastname: Imai
mesh_terms: D000375:Aging / Q000378:metabolism / Q000473:pathology / Q000502:physiology*; D000818:Animals; D006570:Heterochromatin / Q000502:physiology; D006655:Histone Deacetylases / Q000502:physiology*; D006801:Humans; D008136:Longevity; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D015398:Signal Transduction; D038281:Silent Information Regulator Proteins, Saccharomyces cerevisiae; D056564:Sirtuin 1; D056565:Sirtuin 2; D037761:Sirtuins; D015534:Trans-Activators / Q000502:physiology*
chemical_list: D006570:Heterochromatin; D038281:Silent Information Regulator Proteins, Saccharomyces cerevisiae; D015534:Trans-Activators; C087778:SIR2 protein, S cerevisiae; C447939:SIRT1 protein, human; D056564:Sirtuin 1; D056565:Sirtuin 2; D037761:Sirtuins; D006655:Histone Deacetylases