title: The influence of dietary microbial phytase and calcium on the accumulation of cadmium in different organs of pigs.
abstract: A total of 72 barrows (initial body weight 16.7 kg) was used, to evaluate the influence of microbial phytase supplementation alone or in combination with calcium to barley soybean meal diets on the accumulation of cadmium (Cd) in kidney, liver, muscle, brain and bone. The control group received the basal diet with 6 g Ca and a low native Cd concentration of 0.03 mg/kg dry matter (DM). In the experimental groups 2, 3, 4 and 5 dietary cadmium concentration was elevated to 0.78 mg/kg DM. The diet of group 3 was supplemented with 800 U microbial phytase/kg, the diet of group 4 with 6 g Ca/kg. The diet of group 5 contained both supplements. The addition of microbial phytase caused an increase of Cd retention in kidney and liver at 30 and 50 kg body weight. This effect was counteracted by the contemporary addition of calcium. A supplementation of Ca alone showed no effect on the Cd accumulation in kidney and liver. In muscle, brain and bone no effects of phytase and calcium on the accumuLation of Cd could be found.
authors.affiliation: Hohenheim University, Institute of Animal Nutrition, Stuttgart, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Zacharias
authors.forename: H J
authors.initials: HJ
authors.lastname: Lantzsch
authors.forename: W
authors.initials: W
authors.lastname: Drochner
mesh_terms: D010832:6-Phytase / Q000494:pharmacology*; D000818:Animals; D001835:Body Weight; D001842:Bone and Bones / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002104:Cadmium / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism / Q000494:pharmacology*; D001467:Hordeum / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D010833:Phytic Acid / Q000494:pharmacology; D013552:Swine; D014018:Tissue Distribution; D015032:Zinc / Q000494:pharmacology
chemical_list: D002104:Cadmium; D010833:Phytic Acid; D010832:6-Phytase; D015032:Zinc; D002118:Calcium