[A case of severe adult measles pneumonia--efficacy of combination of steroid pulse therapy, high-dose vitamin A and gamma globulins].
A 33 year-old female was admitted with facial, trunk and limb eruptions, conjunctiva intrahemorrhage, Koplik's spots in the pharynx and severe hypoxemia after fever and upper respiratory tract symptom. Infiltrative shadow of the whole right lung was seen on chest radiography. Fine crackles were seen in the lower left lung and in the whole right lung. Severe inflammation and liver dysfunction were indicated by blood test. Measles antibody IgM was high. The abnormal interstitial shadows were confirmed in greater detail by chest computed tomography. Her condition was diagnosed as measles pneumonia. A combination therapy with steroid pulse, high dose vitamin A, and gamma globulin was started, after which the patient gradually improved, indicating the effectiveness of this combination therapy for severe adult measles pneumonia.
Tatsukawa
M
M
Department of General Medicine, Kyushu University Hospital.
Sawayama
Y
Y
Nabeshima
S
S
Hayashi
J
J
Kashiwagi
S
S
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008457:Measles / Q000628:therapy*; D008775:Methylprednisolone / Q000008:administration & dosage*; D011024:Pneumonia, Viral / Q000628:therapy*; D020551:Pulse Therapy, Drug; D014801:Vitamin A / Q000008:administration & dosage*; D005719:gamma-Globulins / Q000008:administration & dosage*
D000893:Anti-Inflammatory Agents; D005719:gamma-Globulins; D014801:Vitamin A; D008775:Methylprednisolone