title: Pulsed electron paramagnetic resonance methods for macromolecular structure determination.
abstract: Pulsed electron paramagnetic resonance (EPR) distance measurement techniques target macromolecular structure elucidation at both the local and global level. Recent developments in pulse microwave technology and high-field EPR have led to the development of a variety of pulsed EPR distance measurement techniques. These methods have emerged as powerful tools for the determination of structure/function relationships in macromolecular systems. In this review article, we discuss recent applications of long-range and short-range EPR distance measurements.
authors.affiliation: Department of Chemistry, Yale University, New Haven, CT 06520, USA. k.lakshmi@yale.edu
authors.forename: K V
authors.initials: KV
authors.lastname: Lakshmi
authors.forename: G W
authors.initials: GW
authors.lastname: Brudvig
mesh_terms: D000818:Animals; D001400:Azurin / Q000031:analogs & derivatives* / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D046911:Macromolecular Substances; D008958:Models, Molecular; D019001:Nitric Oxide Synthase / Q000737:chemistry; D052250:Nitric Oxide Synthase Type III; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry
chemical_list: D046911:Macromolecular Substances; D045322:Photosynthetic Reaction Center Complex Proteins; C012543:rusticyanin; D001400:Azurin; D019001:Nitric Oxide Synthase; D052250:Nitric Oxide Synthase Type III