Results of the MXM Digisonic auditory brainstem implant clinical trials in Europe.
OBJECTIVE
To assess the potential benefit of the MXM auditory brainstem implant for patients with neurofibromatosis type 2.


METHODS
Retrospective case review.


METHODS
Tertiary referral centers.


METHODS
Fourteen patients with neurofibromatosis type 2 and bilateral acoustic neuromas underwent implantation with the MXM auditory brainstem implant during surgery to remove the second-side tumor.


RESULTS
There were no complications related to the auditory brainstem implantation. Auditory sensations were present for 12 of 14 patients (86%). Global results indicated an improved quality of life for the patients receiving auditory sensations, in part because of their auditory orientation within the environment. Eighty-nine percent of patients tested with an open-set sentence test demonstrated enhancement of speech understanding as a result of lip-reading improvement when auditory brainstem implant sound was combined with lip-reading. A few patients (36%) had some speech understanding in sound-only mode. One patient was able to have limited phone conversations.


CONCLUSIONS
These results indicate that significant auditory benefit can be derived from the MXM auditory brainstem implant.
Vincent
Christophe
C
Department of Otorhinolaryngology, University of Lille, Lille, France.
Zini
Carlo
C
Gandolfi
Angelo
A
Triglia
Jean-Michel
JM
Pellet
William
W
Truy
Eric
E
Fischer
Georges
G
Maurizi
Maurizio
M
Meglio
Mario
M
Lejeune
Jean-Paul
JP
Vaneecloo
François-Michel
FM
D000293:Adolescent; D000328:Adult; D001307:Auditory Perception / Q000502:physiology; D002986:Clinical Trials as Topic; D003638:Deafness / Q000209:etiology / Q000601:surgery; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016518:Neurofibromatosis 2 / Q000150:complications; D009464:Neuroma, Acoustic / Q000150:complications; D013506:Otologic Surgical Procedures / Q000379:methods; D011182:Postoperative Care; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome