title: Pediatric reference ranges for osteocalcin measured by the Immulite analyzer.
abstract: Pediatric reference ranges for osteocalcin measured by a new, fully automated, chemiluminescent immunometric assay on the Immulite immunoanalyzer are presented. Samples from 627 children, ranging from newborns to 18 years of age, were measured. Osteocalcin values are generally higher in children than in adults, highest levels being reached during the puberty growth spurt at about 12 years in girls and 14 years in boys, thereafter rapidly declining towards adult levels.
authors.affiliation: Univ-Kinderklinik, Freiburg, Germany. sey@kikli.ukl.uni-freiburg.de
authors.forename: H H
authors.initials: HH
authors.lastname: Seydewitz
authors.forename: M
authors.initials: M
authors.lastname: Henschen
authors.forename: W
authors.initials: W
authors.lastname: Kühnel
authors.forename: M
authors.initials: M
authors.lastname: Brandis
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000704:Analysis of Variance; D001774:Blood Chemical Analysis / Q000295:instrumentation / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods*; D007223:Infant; D007231:Infant, Newborn; D008163:Luminescent Measurements; D008297:Male; D015675:Osteocalcin / Q000097:blood*; D011627:Puberty / Q000097:blood; D012016:Reference Values
chemical_list: D015675:Osteocalcin