Spontaneous haemoperitoneum from surreptitious ingestion of a rodenticide.
Superwarfarins have progressively replaced warfarin as rodenticides as they are more potent and have a longer anticoagulant activity. Human exposure may be complicated by spontaneous haemorrhage in various sites. We report the case of a 51-year-old woman who was admitted with spontaneous haemoperitoneum and intramural haematoma along the small intestine. After the evidence of a deficit of vitamin K1-dependent clotting factors (II, VII, IX, X), the patient admitted that she was chronically ingesting difenacoum. She was successfully treated with fresh frozen plasma and vitamin K1. Follow-up was not accepted.
Soubiron
L
L
Department of Intensive Care, Cliniques Universitaires St-Luc, Brussels, Belgium.
Hantson
P
P
Michaux
I
I
Lambert
M
M
Mahieu
P
P
Pringot
J
J
D015110:4-Hydroxycoumarins / Q000506:poisoning*; D000925:Anticoagulants / Q000506:poisoning*; D017809:Fatal Outcome; D005260:Female; D006465:Hemoperitoneum / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D012378:Rodenticides / Q000506:poisoning*
D015110:4-Hydroxycoumarins; D000925:Anticoagulants; D012378:Rodenticides; C012903:difenacoum