[A study of clinicopathology and lectin immunohistochemistry in unicystic ameloblastoma].
OBJECTIVE
To investigate clinicopathological characteristics of unicystic ameloblastoma and histological markers for differential diagnosis with odontogenic cyst.


METHODS
HE staining and histopathological observation, and lectin UEA-1, BSA-1 immunohistochemistry staining.


RESULTS
40 cases of unicystic ameloblastoma were divided histologically into 3 groups. In odontogenic cysts, most of epithelial lining showed positive binding with UEA-1 and BSA-1, whereas negative reactions were obtained for these two lectins in the epithelial components of unicystic ameloblastoma and solid or multicystic ameloblastoma, except for limited UEA-1 or BSA-1 binding to markedly keratinized tumor cells in several cases of ameloblastomas.


CONCLUSIONS
The unicystic ameloblastoma is a distinct entity which has characteristic clinicopathology. The lectin staining for UEA-1 and BSA-1 is a useful histological aid to differential diagnosis between unicystic ameloblastoma and odontogenic cyst.
Wang
Y
Y
School of Stomatology, Hubei Medical University, Wuhan 430079.
Wang
S
S
Chen
X
X
D000293:Adolescent; D000564:Ameloblastoma / Q000378:metabolism / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D037102:Lectins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009807:Odontogenic Cysts / Q000378:metabolism / Q000473:pathology*; D037121:Plant Lectins
D037102:Lectins; D037121:Plant Lectins; C036850:Ulex europaeus lectins