[Clinical observation of the effect of shuxinsu capsule in treating angina pectoris].
OBJECTIVE
To observe the therapeutic effect of Shuxinsu capsule (SXSC) in treating angina pectoris patients.


METHODS
One hundred and fifty angina pectoris patients were divided into two groups. Group A (80 cases), randomly divided into two subgroups, SXSC treated and Yixin oral liquid (YXOL) control group, each group consisted of 40 cases. Group B (70 cases) was an openly treated group (OTG).


RESULTS
17 cases were markedly effective in the SXSC treated group in relieving the symptoms, effective were 16, the total effective rate was 82.50%, while in the control group, the markedly effective cases, the effective cases and the total effective rate were 13, 16 and 72.50% respectively; there was significant difference between these two groups (u = 1.99, P < 0.05). In the treated group (SXSC and OTG) of 110 cases, the markedly effective, effective cases on ECG were 34 and 30 respectively. The total effective rate was 58.18%, higher than that of the control group, which was 55.00%, but the difference was insignificant. The activity of SOD in RBC and the amount of plasma LPO were significantly different after treatment in the SXSC group. Both of the medications had effect to reduce serum total cholesterol (TC) and triglyceride (TG), the TC was lower and high density lipoprotein-cholesterol (HDL-C) higher significantly after treatment in the SXSC group.


CONCLUSIONS
SXSC has significant effect on angina pectoris.
Li
H
H
Xiyuan Hospital, China Academy of TCM, Beijing (100091).
Cui
L
L
Zhou
W
W
D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D002214:Capsules; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005894:Panax / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D012503:Saponins / Q000302:isolation & purification / Q000627:therapeutic use
D002214:Capsules; D004365:Drugs, Chinese Herbal; D012503:Saponins