title: [Treatment of syphilis in pregnancy and its perinatal prognosis].
abstract: OBJECTIVE
  To investigate the effects of treatment of syphilis in pregnancy on perinatal prognosis.
  
  
  METHODS
  Patients of syphilis in pregnancy from Hainan Provincial People's Hospital and Haikou Municipal Maternal and Child Health Center during 1995.1 to 2001.1 were collected for retrospective analysis. Pregnant women with syphilis were divided into treated group and untreated group according to whether they received penicillin anti-syphilis treatment or not during pregnancy.
  
  
  RESULTS
  The total number of deliveries in the 2 hospitals during that period was 18,701, and 61 out of 9,805 women screened for syphilis were positive, giving an incidence of 6.2/1000. The perinatal mortality rates were 11.2% in treated group and 83.3% in untreated group, and incidences of congenital syphilis were 17.6% and 72.7% respectively.
  
  
  CONCLUSIONS
  Syphilis in pregnancy is a serious complication to harm the fetus. Screening of syphilis during pregnancy is necessary, and penicillin treatment is effective which may reduce the perinatal mortality rate and the birth of congenital syphilis baby.
authors.affiliation: Department of Obstetrics and Gynecology, Provincial People's Hospital of Hainan, Haikou 570311, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Xu
authors.forename: X
authors.initials: X
authors.lastname: Lu
authors.forename: Y
authors.initials: Y
authors.lastname: Ling
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D011379:Prognosis; D012189:Retrospective Studies; D013587:Syphilis / Q000150:complications / Q000188:drug therapy*