title: Effectiveness of two fluoride dentifrices to arrest root carious lesions.
abstract: OBJECTIVE
  To compare the effectiveness of Prevident 5000 Plus (5,000 ppm F) and Colgate Winterfresh Gel (1100 ppm F) to arrest root carious lesions.
  
  
  METHODS
  201 subjects with at least one root carious lesion were recruited from dental school patients. They were randomly assigned to use either Prevident 5000 Plus (5000 ppm F) or Colgate Winterfresh Gel (1100 ppm F) as sodium fluoride in the same silica base. Measurements of lesion hardness, area, distance from the gingival margin, cavitation and plaque were recorded at baseline and after 3 months by a single examiner.
  
  
  RESULTS
  After 3 months 38% of subjects using Prevident 5000 Plus and 10% using Winterfresh Gel had one or more lesions that had become hard (P < 0.001). Non-cavitated lesions at baseline were more likely to become hard than cavitated lesions. Compared to the Winterfresh group there was significant increase in the distance from the base of the lesion to the gingival margin and plaque scores were reduced in those using Prevident 5000 Plus.
authors.affiliation: Dental School, Royal Victoria Hospital, Queen's University, Belfast, Northern Ireland, United Kingdom. e.lynch@mds.qmw.ac.uk
authors.forename: E
authors.initials: E
authors.lastname: Lynch
authors.forename: A
authors.initials: A
authors.lastname: Baysan
authors.forename: R
authors.initials: R
authors.lastname: Ellwood
authors.forename: R
authors.initials: R
authors.lastname: Davies
authors.forename: L
authors.initials: L
authors.lastname: Petersson
authors.forename: P
authors.initials: P
authors.lastname: Borsboom
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D045424:Complex Mixtures; D003773:Dental Plaque / Q000517:prevention & control; D003774:Dental Plaque Index; D003802:Dentifrices / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use*; D005500:Follow-Up Studies; D005881:Gingiva / Q000473:pathology; D005891:Gingivitis / Q000517:prevention & control; D006244:Hardness; D006801:Humans; D008297:Male; D008875:Middle Aged; D017213:Root Caries / Q000473:pathology / Q000517:prevention & control*; D012822:Silicon Dioxide; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000627:therapeutic use; D013223:Statistics as Topic; D014089:Tooth Remineralization; D016896:Treatment Outcome
chemical_list: D002327:Cariostatic Agents; C408633:Colgate Winterfresh Fluoride Gel; D045424:Complex Mixtures; D003802:Dentifrices; D012822:Silicon Dioxide; D012969:Sodium Fluoride; D005459:Fluorides