Handling of computational in vitro/in vivo correlation problems by Microsoft Excel: I. Principles and some general algorithms.
Most computations in the field of in vitro/in vivo correlations can be handled directly by Excel worksheets, without the need for specialized software. Following a summary of Excel features, applications are illustrated for numerical computation of AUC and Mean, Wagner-Nelson and Loo-Riegelman absorption plots, and polyexponential curve fitting.
Langenbucher
Frieder
F
BioVista LLC, Ruechligweg 101, CH-4125, Riehen, Switzerland. mysickaj@ivivc.com
D000465:Algorithms; D008432:Mathematical Computing; D015233:Models, Statistical; D012984:Software / Q000706:statistics & numerical data*