title: Preliminary results of the FRO project: chromosomal abnormalities in primary uveal melanoma.
abstract: Uveal melanoma is the most common primary intraocular tumor in adults in the western world. Recent studies indicate that the presence of cytogenetic abnormalities in tumor cells is strongly linked with prognosis. The purpose of this project is the detection of chromosomal abnormalities in a series of frozen tumors (retrospective study) and of fresh tumor tissues (prospective study) and to correlate these results with other prognostic factors and survival.
authors.affiliation: Dienst Oogziekten, St Rafaël UZ Leuven.
authors.forename: D
authors.initials: D
authors.lastname: Cools
authors.forename: M
authors.initials: M
authors.lastname: Debiec-Rychter
authors.forename: R
authors.initials: R
authors.lastname: Parys-Van Ginderdeuren
authors.forename: A
authors.initials: A
authors.lastname: Hagemeijer-Hausman
authors.forename: J
authors.initials: J
authors.lastname: Van den Oord
authors.forename: W
authors.initials: W
authors.lastname: Spileers
mesh_terms: D000328:Adult; D001706:Biopsy; D002869:Chromosome Aberrations; D002893:Chromosomes, Human, Pair 3; D002896:Chromosomes, Human, Pair 6; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D007621:Karyotyping; D008545:Melanoma / Q000473:pathology*; D011446:Prospective Studies; D012189:Retrospective Studies; D014604:Uveal Neoplasms / Q000235:genetics* / Q000473:pathology*