[A case-control study of risk factors for type 2 diabetes mellitus].
OBJECTIVE
The prevalence of type 2 diabetes mellitus is increasing so to investigate the relation between insulin resistance and development of type 2 diabetes mellitus.


METHODS
A 1:1 pair-matched case-control study was conducted with diagnostic criteria recommended by WHO. Controls matched with cases by age, sex, race and resident place. Information on demographic, history of disease, life-style were obtained through questionnaire. Variables including fasting blood glucose (FBG), fasting blood insulin (FBI), total cholesterol (TC), triglyceride (TG), waist-to-hip ratio (WHR), waist-to-thigh ratio (WTR) were measured for every subject. Conditional logistics regression was used for data analysis.


RESULTS
The results showed that insulin resistance, history of hypertension and waist-to-hip ratio were associated with type 2 diabetes mellitus. The values of OR were 1.530 (95% CI: 1.234-1.896), 4.833 (95% CI: 1.966-11.703), 21.996 (95% CI: 5.461-88.593), respectively.


CONCLUSIONS
Insulin resistance was risk factor causing type 2 diabetes mellitus, independent of other risk factors.
Ma
J
J
Public Health College, Tianjin Medical University, Tianjin 300070, China.
Wang
J
J
Wang
Z
Z
D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D012307:Risk Factors