title: Results of the MXM Digisonic auditory brainstem implant clinical trials in Europe.
abstract: OBJECTIVE
  To assess the potential benefit of the MXM auditory brainstem implant for patients with neurofibromatosis type 2.
  
  
  METHODS
  Retrospective case review.
  
  
  METHODS
  Tertiary referral centers.
  
  
  METHODS
  Fourteen patients with neurofibromatosis type 2 and bilateral acoustic neuromas underwent implantation with the MXM auditory brainstem implant during surgery to remove the second-side tumor.
  
  
  RESULTS
  There were no complications related to the auditory brainstem implantation. Auditory sensations were present for 12 of 14 patients (86%). Global results indicated an improved quality of life for the patients receiving auditory sensations, in part because of their auditory orientation within the environment. Eighty-nine percent of patients tested with an open-set sentence test demonstrated enhancement of speech understanding as a result of lip-reading improvement when auditory brainstem implant sound was combined with lip-reading. A few patients (36%) had some speech understanding in sound-only mode. One patient was able to have limited phone conversations.
  
  
  CONCLUSIONS
  These results indicate that significant auditory benefit can be derived from the MXM auditory brainstem implant.
authors.affiliation: Department of Otorhinolaryngology, University of Lille, Lille, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Vincent
authors.forename: Carlo
authors.initials: C
authors.lastname: Zini
authors.forename: Angelo
authors.initials: A
authors.lastname: Gandolfi
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Triglia
authors.forename: William
authors.initials: W
authors.lastname: Pellet
authors.forename: Eric
authors.initials: E
authors.lastname: Truy
authors.forename: Georges
authors.initials: G
authors.lastname: Fischer
authors.forename: Maurizio
authors.initials: M
authors.lastname: Maurizi
authors.forename: Mario
authors.initials: M
authors.lastname: Meglio
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Lejeune
authors.forename: François-Michel
authors.initials: FM
authors.lastname: Vaneecloo
mesh_terms: D000293:Adolescent; D000328:Adult; D001307:Auditory Perception / Q000502:physiology; D002986:Clinical Trials as Topic; D003638:Deafness / Q000209:etiology / Q000601:surgery; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016518:Neurofibromatosis 2 / Q000150:complications; D009464:Neuroma, Acoustic / Q000150:complications; D013506:Otologic Surgical Procedures / Q000379:methods; D011182:Postoperative Care; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome