title: [The effect of a nonprotein spleen factor on the course of delayed-type hypersensitivity and graft versus host reactions].
abstract: The effects of splenoside on the reactions of delayed-type hypersensitivity and graft versus host were investigated. Even single splenoside injection (50 mg/10 g b.w.) increased graft versus host reaction in newborn mice-hybrids F1. Splenoside influences the delayed-type hypersensitivity reaction in dose-depending manner: the dose of 50 mg/10 g increases the reaction and 100 mg/10 g decreases it.
authors.affiliation: V.P. Komisarenko Institute of Endocrinology and Metabolism, Kiev.
authors.forename: L M
authors.initials: LM
authors.lastname: Bykova
authors.forename: H L
authors.initials: HL
authors.lastname: Synel'nykova
authors.forename: B V
authors.initials: BV
authors.lastname: Oliĭnyk
mesh_terms: D000818:Animals; D001685:Biological Factors / Q000008:administration & dosage / Q000494:pharmacology*; D004306:Dose-Response Relationship, Immunologic; D006087:Graft vs Host Reaction / Q000187:drug effects* / Q000276:immunology*; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D009705:Nucleosides / Q000008:administration & dosage / Q000494:pharmacology*; D013154:Spleen / Q000276:immunology / Q000502:physiology
chemical_list: D001685:Biological Factors; D009705:Nucleosides
vernacular_title: Perebih reaktsiï hiperchutlyvosti upovil'nenoho typu ta "transplantat proty khaziaïna" pid vplyvom nebilkovoho chynnyka selezinky.