The severity of hepatic lesion after intraperitoneal JHMV infection in IFN-gamma deficient mice is parallel to viral replication in hepatocytes in vitro.
Kyuwa
S
S
Division of Microbiology and Genetics, Center for Animal Resources and Development, Kumamoto University, Kumamoto, Japan.
Kawamura
S
S
Shibata
S
S
Machii
K
K
Tagawa
Y
Y
Iwakura
Y
Y
Urano
T
T
D000818:Animals; D002478:Cells, Cultured; D018352:Coronavirus Infections / Q000473:pathology / Q000503:physiopathology / Q000821:virology; D006524:Hepatitis, Viral, Animal / Q000473:pathology / Q000503:physiopathology / Q000821:virology; D022781:Hepatocytes / Q000821:virology*; D007274:Injections, Intraperitoneal; D007371:Interferon-gamma / Q000172:deficiency* / Q000235:genetics; D008099:Liver / Q000473:pathology* / Q000821:virology; D017737:Macrophages, Peritoneal / Q000821:virology; D051379:Mice; D008807:Mice, Inbred BALB C; D018345:Mice, Knockout; D006517:Murine hepatitis virus / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology; D012720:Severity of Illness Index; D014779:Virus Replication
D007371:Interferon-gamma