[Tropacin in the treatment of patients with the hyperactive urinary bladder].
OBJECTIVE
To examine effectiveness and tolerance of tropacin in patients with hyperactive urinary bladder (HAUB).


METHODS
62 patients aged between 19 and 82 with hyperactive bladder have received tropacin in a dose 3-10 mg twice a day for 12 weeks. Of them 31 had idiopathic detrusor unstability (IDUS), 10 had sensory urgent disorders (SUD), 21 suffered from detrusor hyperreflexia (DHR).


RESULTS
In IDUS patients 12-week tropacin administration reduced mean daily number of urination from 14.3 to 10.9, mean daily number of episodes of inperative enuresis diminished from 3.9 to 2.2. DHR patients showed the above decrease from 15.2 to 12.7 and 4.1 to 2.2, respectively. In sensory urgency tropacin was less effective.


CONCLUSIONS
Tropacin is effective and safe medicine for treatment of IDUS and DHR.
Krivoborodov
G G
GG
Shvarts
P G
PG
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D014326:Tropanes / Q000009:adverse effects / Q000627:therapeutic use*; D014549:Urinary Incontinence / Q000188:drug therapy; D014555:Urination Disorders / Q000188:drug therapy*
D018727:Muscarinic Antagonists; D014326:Tropanes; C003727:tropacine
Tropatsin v lechenii bol'nykh s giperaktivnym mochevym puzyrem.