Dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil associated toxicity.
van Kuilenburg
A B
AB
Academic Medical Center, University of Amsterdam, Emma Children's Hospital, The Netherlands.
Haasjes
J
J
Van Lenthe
H
H
Zoetekouw
L
L
Waterham
H R
HR
Vreken
P
P
van Gennip
A H
AH
D000483:Alleles; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil / Q000009:adverse effects*; D006579:Heterozygote; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000166:cytology / Q000187:drug effects; D010088:Oxidoreductases / Q000172:deficiency / Q000235:genetics*
D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil