A case of a methadone-induced movement disorder.
OBJECTIVE
To increase awareness of the possibility of opioid induced movement disorders.


METHODS
A university-affiliated Veterans Affairs Hospital.


METHODS
A patient with upper extremity pain due to complex regional pain syndrome type I (reflex sympathetic dystrophy).


METHODS
Attempted pain control with methadone.


CONCLUSIONS
After failing many attempts at control, the authors were able to provide their patient significant pain relief from her complex regional pain syndrome type I using methadone. Unfortunately, the patient eventually developed a movement disorder, characterized by tremor, choreiform movements, and a gait abnormality, probably related to this opioid. The authors conclude that, while this type of movement disorder is uncommon, clinicians need to be aware of opioid-induced movement disorders, because they are disturbing to patients and often easily treated.
Clark
J D
JD
Veterans Affairs Palo Alto Health Care System, California 94304, USA. djclark@stanford.edu
Elliott
J
J
D000328:Adult; D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000627:therapeutic use; D002819:Chorea / Q000150:complications*; D005260:Female; D005684:Gait / Q000187:drug effects*; D006801:Humans; D008691:Methadone / Q000009:adverse effects* / Q000627:therapeutic use; D012019:Reflex Sympathetic Dystrophy / Q000188:drug therapy; D014202:Tremor / Q000139:chemically induced*
D000701:Analgesics, Opioid; D008691:Methadone