[Effects of Streptococcus sanguis on blood composition, blood pressure and cardiac dysfunction in rabbis].
OBJECTIVE
To investigate effect of streptococcus sanguis on blood cell and cardiopulmonary changes.


METHODS
133-79 strains of streptococcus sanguis (aggregation positive) were infused intravenously into rabbits. Before and 5, 10, 20, 30, 45, 60 min after infuse platelets count, leukocytes count, blood pressure and ECG were measured.


RESULTS
After infused intravenously, both platelets and leukocytes count decreased remarkably (P < 0.01, n = 12). The ECG showed ST segment depression (> 0.06 mV). Diphasic blood pressure occurred (first hypertensive then hypotensive).


CONCLUSIONS
Streptococcus sanguis 133-79 strains in circulation system might cause myocardia ischemia, blood pressure changes, peripheral circulation platelets and leukocytes decrease remarkably.
Chen
H
H
Department of Oral Medicine, Affiliated Hospital of Stomatology, Medical School, Zhejiang University, Hangzhou 310031, China.
Zhao
M
M
Li
J
J
D000818:Animals; D001773:Blood Cells / Q000473:pathology*; D001792:Blood Platelets / Q000473:pathology; D001794:Blood Pressure; D004195:Disease Models, Animal; D004562:Electrocardiography; D005260:Female; D007962:Leukocytes / Q000473:pathology; D008297:Male; D017202:Myocardial Ischemia / Q000209:etiology*; D011817:Rabbits; D013290:Streptococcal Infections / Q000503:physiopathology*; D013298:Streptococcus sanguis / Q000502:physiology*