Methylated and non methylated thiopurine nucleotide ratio (Me6-MPN/6-TGN): usefulness in the monitoring of azathioprine therapy?
Boulieu
R
R
Université Claude Bernard Lyon 1, Département de Pharmacie Clinique, Pharmacocinétique et d'Evaluation du Médicament, France.
Dervieux
T
T
Gallant
I
I
Sauviat
M
M
Bertocchi
M
M
Mornex
J F
JF
D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use*; D019175:DNA Methylation; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006150:Guanine Nucleotides / Q000378:metabolism*; D016041:Heart-Lung Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D015122:Mercaptopurine / Q000378:metabolism*; D008780:Methyltransferases / Q000378:metabolism; D008875:Middle Aged; D008991:Monitoring, Physiologic; D013873:Thionucleotides / Q000378:metabolism*
D006150:Guanine Nucleotides; D007166:Immunosuppressive Agents; D013873:Thionucleotides; C003964:6-thioguanylic acid; D015122:Mercaptopurine; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D001379:Azathioprine