title: Proteins involved in the production and perception of oligosaccharides in relation to plant and animal development.
abstract: Chitin oligosaccharides and their derivatives are involved in developmental and defence-related signalling pathways. Major advances include the structural identification of lectins involved in development that bind chitin oligosaccharides and the links between chitin oligosaccharide and hyaluronan synthesis. Also, recent advances in the understanding of the biological role of oligosaccharides are summarised in a model for multistep glycan recognition.
authors.affiliation: Leiden University, Institute of Molecular Plant Sciences, The Netherlands.
authors.forename: P P
authors.initials: PP
authors.lastname: van der Holst
authors.forename: H R
authors.initials: HR
authors.lastname: Schlaman
authors.forename: H P
authors.initials: HP
authors.lastname: Spaink
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001081:Apyrase / Q000378:metabolism; D002240:Carbohydrate Sequence; D002686:Chitin / Q000096:biosynthesis / Q000737:chemistry; D002688:Chitinases / Q000235:genetics / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000235:genetics / Q000378:metabolism; D006128:Growth; D006801:Humans; D037102:Lectins / Q000378:metabolism; D008954:Models, Biological; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000096:biosynthesis* / Q000737:chemistry; D063245:Plant Development; D037121:Plant Lectins; D011506:Proteins / Q000378:metabolism*; D011509:Proteoglycans / Q000096:biosynthesis / Q000737:chemistry; D018125:Receptors, Transforming Growth Factor beta / Q000096:biosynthesis / Q000737:chemistry; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction
chemical_list: D037102:Lectins; D009844:Oligosaccharides; D037121:Plant Lectins; D011506:Proteins; D011509:Proteoglycans; D018125:Receptors, Transforming Growth Factor beta; D002686:Chitin; C071736:betaglycan; D006026:Glycoside Hydrolases; D002688:Chitinases; D001081:Apyrase