title: Metachronous contralateral germ cell tumor 7 years after management of testicular intraepithelial neoplasia by chemotherapy and multiple control biopsies.
abstract: We report about a metachronous germ cell tumor 7 years after chemotherapy of advanced testicular cancer and contralateral testicular intraepithelial neoplasia (TIN). Chemotherapy can not safely eradicate TIN. The safest treatment for TIN remains low dose radiation.
authors.affiliation: Department of Urology, University of Essen, Medical School, Germany.
authors.forename: C
authors.initials: C
authors.lastname: von Ostau
authors.forename: S
authors.initials: S
authors.lastname: Krege
authors.forename: M
authors.initials: M
authors.lastname: Hartmann
authors.forename: H
authors.initials: H
authors.lastname: Rübben
mesh_terms: D000328:Adult; D001706:Biopsy; D002278:Carcinoma in Situ / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000473:pathology; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D013737:Testis / Q000473:pathology*; D013997:Time Factors; D016896:Treatment Outcome