title: Pregnancy outcome after maternal poisoning with brodifacoum, a long-acting warfarin-like rodenticide.
abstract: BACKGROUND
  Brodifacoum is a potent warfarin-like anticoagulant used in many rat-poisoning products. Its availability has led to several reported human ingestions, none previously reported in pregnancy.
  
  
  METHODS
  A woman presented at 22 weeks' gestation in hemorrhagic diathesis, attributed to the ingestion of rat poison containing brodifacoum several days earlier. Aggressive vitamin K therapy controlled the maternal coagulopathy, and no fetal hemorrhage was observed by sonography. Her subsequent prenatal course and delivery were unremarkable, and she was delivered of a healthy infant, who has remained well for at least 1 year.
  
  
  CONCLUSIONS
  In this patient, brodifacoum ingestion in pregnancy caused substantial maternal hemorrhage, but no fetal hemorrhage or teratogenic effects were observed.
authors.affiliation: University of Cincinnati College of Medicine, Department of Obstetrics and Gynecology, OH, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Zurawski
authors.forename: E A
authors.initials: EA
authors.lastname: Kelly
mesh_terms: D015110:4-Hydroxycoumarins / Q000008:administration & dosage / Q000506:poisoning*; D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000139:chemically induced*; D011256:Pregnancy Outcome; D012378:Rodenticides / Q000008:administration & dosage / Q000506:poisoning*; D013406:Suicide, Attempted
chemical_list: D015110:4-Hydroxycoumarins; D012378:Rodenticides; C013418:bromfenacoum