Transfusion-mediated Yersinia enterocolitica septicemia in an adult patient with beta-thalassemia.
We report a case of transfusion-mediated Yersinia enterocolitica septicemia in a 43-y-old woman with homozygous beta-thalassemia. Two h after transfusion of 3 units of red blood cells the patient suffered high-grade fever and shaking chills. Y. enterocolitica serotype O3 grew in blood cultures. Prolonged treatment with i.v. ceftriaxone plus ciprofloxacin led to a favorable outcome. Transfusion-associated Y. enterocolitica septicemia has not previously been reported in an adult beta-thalassemic patient from the Mediterranean area. Our report is particularly important, because of the high incidence of chronically transfused thalassemic patients in Mediterranean countries.
Roussos
A
A
Department of Internal Medicine, General Hospital Sotiria, Athens, Greece.
Stambori
M
M
Aggelis
P
P
Kanavaki
S
S
Garzonis
P
P
Makarona
M
M
Kapralos
C
C
Karambela
S
S
Dalamaga
A
A
Ferti
A
A
D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D065227:Transfusion Reaction; D016896:Treatment Outcome; D015009:Yersinia Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D015008:Yersinia enterocolitica / Q000302:isolation & purification*; D017086:beta-Thalassemia / Q000628:therapy*
D000890:Anti-Infective Agents; D002511:Cephalosporins; D002939:Ciprofloxacin; D002443:Ceftriaxone