Myasthenia gravis and disorders of neuromuscular transmission.
Myasthenia gravis is a disorder of neuromuscular transmission that occurs in congenital and acquired autoimmune forms. Acquired myasthenia gravis is probably the most common neuromuscular disorder in dogs that can be diagnosed and treated. An early, accurate diagnosis and appropriate therapy is of utmost importance to a good clinical outcome in this disorder. This article focuses on the diagnosis and treatment of acquired myasthenia gravis in dogs and cats with brief discussions of other disorders of neuromuscular transmission, including congenital myasthenia gravis, tick paralysis, botulism, and organophosphate intoxication.
Shelton
G Diane
GD
Department of Pathology, School of Medicine, University of California, San Diego, La Jolla 92093-0612, USA. gshelton@ucsd.edu
D000818:Animals; D002371:Cat Diseases / Q000151:congenital / Q000175:diagnosis*; D002415:Cats; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000151:congenital / Q000175:diagnosis*; D004285:Dogs; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000662:veterinary*; D010808:Physical Examination / Q000662:veterinary*