title: A practical six-step synthesis of (S)-camptothecin.
abstract: An asymmetric synthesis of (S)-camptothecin (1) has been accomplished in six steps starting from two commercially available heterocycles. [reaction: see text]
authors.affiliation: Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA. daniel_comins@ncsu.edu
authors.forename: D L
authors.initials: DL
authors.lastname: Comins
authors.forename: J M
authors.initials: JM
authors.lastname: Nolan
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis* / Q000737:chemistry; D002166:Camptothecin / Q000138:chemical synthesis* / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D006571:Heterocyclic Compounds; D002166:Camptothecin