title: Apocrine adenocarcinoma in a golden hamster.
abstract: An apocrine adenocarcinoma was observed in the subcutis of the abdomen of golden hamster. Histologically, the tumor cells irregularly formed multiple layers of cysts and some detached cells were presented in the cystic space. PAS stain with alpha-amylase digestion revealed PAS-positive alpha-amylase-resistant granules in the cytoplasm. Immunohistochemically, cytokeratin was demonstrated in the tumor cells. By electron microscopy, the tumor cells had an oval nucleus with invagination, abundant cytoplasmic organelles and microvilli protruding into the intercellular spaces.
authors.affiliation: Department of Veterinary Pathology, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Urayama
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Shibuya
authors.forename: W
authors.initials: W
authors.lastname: Shirai
authors.forename: M
authors.initials: M
authors.lastname: Matsutani
authors.forename: R
authors.initials: R
authors.lastname: Yamazaki
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D000818:Animals; D001050:Apocrine Glands / Q000473:pathology* / Q000648:ultrastructure; D006224:Cricetinae; D017809:Fatal Outcome; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008854:Microscopy, Electron / Q000662:veterinary; D012376:Rodent Diseases / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*