title: Muscle relaxants in paediatric day case surgery.
abstract: It has been estimated that more than 60% of all paediatric surgery is performed on a day case basis. The benefits of this type of surgery in children include reduced costs, avoidance of the stress of hospitalization and less disruption to family life. The growth of day surgery in children has been facilitated by the development of non-depolarizing neuromuscular blocking agents characterized by short and intermediate duration of action and fewer side-effects. The more rapid onset and shorter duration of action of non-depolarizing neuromuscular blocking agents in children should facilitate the use of these agents in place of succinylcholine for day case procedures.
authors.affiliation: Department of Anaesthesia, University of Manchester, Royal Manchester Children's Hospital, Pendlebury, Manchester M27 4HA, UK. george.meakin@man.ac.uk
authors.forename: G H
authors.initials: GH
authors.lastname: Meakin
mesh_terms: D000556:Ambulatory Surgical Procedures; D000732:Androstanols / Q000008:administration & dosage / Q000493:pharmacokinetics; D001279:Atracurium / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007546:Isoquinolines / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D000077590:Mivacurium; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D009467:Neuromuscular Depolarizing Agents / Q000008:administration & dosage / Q000009:adverse effects; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D000077123:Rocuronium; D013390:Succinylcholine / Q000008:administration & dosage / Q000009:adverse effects; D014673:Vecuronium Bromide / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000493:pharmacokinetics
chemical_list: D000732:Androstanols; D007546:Isoquinolines; D009466:Neuromuscular Blocking Agents; D009467:Neuromuscular Depolarizing Agents; D003473:Neuromuscular Nondepolarizing Agents; D001279:Atracurium; D000077590:Mivacurium; D014673:Vecuronium Bromide; C082938:rapacuronium; D013390:Succinylcholine; C101584:cisatracurium; D000077123:Rocuronium