title: The effectiveness of muscle flaps for the treatment of prosthetic graft sepsis.
abstract: The objective of this study was to assess the efficacy and reliability of muscle flaps in the treatment of prosthetic graft sepsis. A retrospective analysis was performed to assess the outcome of all patients with prosthetic graft sepsis who were treated with a muscle flap at Groote Schuur Hospital between January of 1991 and July of 2000. The specific end points studied were flap survival, limb salvage rate, and mortality. A total of 27 muscle flaps were raised to cover 24 sites of graft sepsis in 21 patients. Twenty-five flaps were performed primarily and two secondarily. The mortality rate was zero. Limb salvage was achieved in 15 of 21 patients (71 percent), with no recurrent sepsis after an average follow-up period of 36 months. The groin was the most common site of infection, with an 86 percent incidence. Eighteen sartorius flaps were raised in the groin. Seventeen of the 18 sartorius flaps survived (94 percent), and a 71 percent limb salvage was achieved with no recurrent sepsis after 36 months of follow-up. This series supports the use of muscle flaps for the treatment of prosthetic graft sepsis. The sartorius flap has been shown to be reliable as a flap in the groin, with successful limb salvage in the majority of patients.
authors.affiliation: Departments of Plastic and Reconstructive Surgery and General Surgery, University of Cape Town, Groote Schuur Hospital, Cape Town, Africa. rgraham@uctgsh1.uct.ac.za
authors.forename: Roger G
authors.initials: RG
authors.lastname: Graham
authors.forename: Patrick O
authors.initials: PO
authors.lastname: Omotoso
authors.forename: Donald A
authors.initials: DA
authors.lastname: Hudson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001807:Blood Vessel Prosthesis; D005260:Female; D006085:Graft Survival; D006119:Groin; D006801:Humans; D007866:Leg / Q000098:blood supply* / Q000601:surgery; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000601:surgery*; D012189:Retrospective Studies; D018805:Sepsis / Q000601:surgery*; D013524:Surgical Flaps; D014656:Vascular Surgical Procedures
chemical_list: D011093:Polyethylene Terephthalates; D011138:Polytetrafluoroethylene