title: The effect of tranexamic acid on the quality of life of women with heavy menstrual bleeding.
abstract: OBJECTIVE
  To investigate whether medical treatment with tranexamic acid would increase the quality of life of women with heavy menstrual bleeding.
  
  
  METHODS
  This open, uncontrolled usage study included 849 women diagnosed with heavy menstrual bleeding and considered eligible for tranexamic-acid treatment. The condition of the women was investigated at baseline and after the first and the third treated menstruation. Quality of life and subjectively experienced state of health were assessed with the aid of a questionnaire. Satisfaction with the treatment was registered.
  
  
  RESULTS
  After the third menstruation, 80% of the women were satisfied with the treatment. Impairment of social activities and impairment at work were greatly reduced by the treatment. Substantial improvements were also recorded with regard to alertness, productivity, cleanliness, spirits, action radius and overall well-being. Adverse reactions to the drug used for the treatment were few and non-serious.
  
  
  CONCLUSIONS
  Medical treatment with tranexamic acid increases quality of life for women with heavy menstrual bleeding.
authors.affiliation: Fruenklinik Friedrich-Ebert-krankenhaus, Friesenstrasse 11, 24531, Neumünster, Germany.
authors.forename: U H
authors.initials: UH
authors.lastname: Winkler
mesh_terms: D000293:Adolescent; D000328:Adult; D000933:Antifibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008595:Menorrhagia / Q000188:drug therapy*; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life; D014148:Tranexamic Acid / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000933:Antifibrinolytic Agents; D006454:Hemoglobins; D014148:Tranexamic Acid