title: [Malignant brain tumors after radiation - glioblastomas after operation and radiation of meningiomas - 2 case reports].
abstract: The authors report 2 cases of glioblastomas subsequent to radiation of intracranial tumors. In the first case, a 47-year old man received radiation therapy after subtotal removal of a temporobasal meningioma. In the second case, a 52-year old women underwent operation of an atypical falcine meningioma and was irradiated postoperatively. - After radiation of meningiomas the development of glioblastomas is described as a rare complication in the literature. A literature analysis of 49 radiation induced tumors revealed that there was no correlation between the radiation dosage and time interval of appearance of the second tumor.
authors.affiliation: Klinik für Neurochirurgie, Helios-Klinikum Erfurt GmbH, Erfurt.
authors.forename: R
authors.initials: R
authors.lastname: Feltz
authors.forename: U
authors.initials: U
authors.lastname: Schalldach
authors.forename: J
authors.initials: J
authors.lastname: Krüger
authors.forename: R
authors.initials: R
authors.lastname: Ruhashya
mesh_terms: D005260:Female; D005909:Glioblastoma / Q000209:etiology*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000532:radiotherapy*; D008579:Meningioma / Q000532:radiotherapy*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors
vernacular_title: Maligne ZNS-Tumoren nach Bestrahlung - Glioblastom nach Operation und Bestrahlung von Meningeomen - zwei Fallberichte.