title: Treatment failure due to methicillin-resistant Staphylococcus aureus (MRSA) with reduced susceptibility to vancomycin.
abstract: We report the first instance in Australia of treatment failure due to a strain of methicillin-resistant Staphylococcus aureus (MRSA) with reduced susceptibility to vancomycin--heteroresistant vancomycin-intermediate S. aureus (hVISA). The infection occurred in a 41-year-old man with multiple risk factors. No transmission of the organism to other patients or the environment was detected. This case may herald the beginning of a new phase of staphylococcal resistance in Australia.
authors.affiliation: Austin and Repatriation Medical Centre, Melbourne, VIC. Peter.Ward@armc.org.au
authors.forename: P B
authors.initials: PB
authors.lastname: Ward
authors.forename: P D
authors.initials: PD
authors.lastname: Johnson
authors.forename: E A
authors.initials: EA
authors.lastname: Grabsch
authors.forename: B C
authors.initials: BC
authors.lastname: Mayall
authors.forename: M L
authors.initials: ML
authors.lastname: Grayson
mesh_terms: D000328:Adult; D003428:Cross Infection / Q000517:prevention & control; D004196:Disease Outbreaks / Q000517:prevention & control; D005260:Female; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D013211:Staphylococcus aureus / Q000187:drug effects*; D017211:Treatment Failure; D020713:Vancomycin Resistance; D014739:Victoria / Q000453:epidemiology