title: Bilateral chylothorax due to retrosternal goiter in a patient with non-Hodgkin's lymphoma.
abstract: Chylous pleural effusion, or chylothorax, usually results from obstruction to or disruption of the thoracic duct. Malignant etiologies are the most common cause of chylothorax, lymphoma accounting for the majority of non-traumatic chylous effusions. We report an unusual case of bilateral chylothorax associated with a retrosternal toxic multinodular goiter in a patient with non-Hodgkin's lymphoma. An ablative dose of 131I was administered with apparent initial clinical improvement. The pathogenesis of chylothorax and therapeutic considerations are discussed.
authors.affiliation: Department of Cancer Medicine, Charing Cross Hospital, London, UK.
authors.forename: M
authors.initials: M
authors.lastname: Simmgen
authors.forename: E S
authors.initials: ES
authors.lastname: Newlands
authors.forename: B M
authors.initials: BM
authors.lastname: Southcott
authors.forename: D M
authors.initials: DM
authors.lastname: Vigushin
mesh_terms: D000368:Aged; D002916:Chylothorax / Q000209:etiology* / Q000473:pathology; D005260:Female; D006044:Goiter, Nodular / Q000150:complications* / Q000209:etiology*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D010996:Pleural Effusion / Q000209:etiology; D013249:Sternum / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes