title: [Efficacy of somatostatin analogs in the treatment of neuroendocrine tumours and paraneoplastic syndromes].
abstract: BACKGROUND
  The authors report their experience with octreotide LAR in the adjuvant treatment of 10 patients suffering from neuroendocrine tumours and paraneoplastic syndromes.
  
  
  METHODS
  All patients were studied preoperatively using traditional radiology and scintigraphy using octreoscan.
  
  
  RESULTS
  Octreoscan was positive in all cases for somatostatin receptors. All patients with neuroendocrine tumours underwent surgery of the primary neoplasm; treatment with somatostatin was commenced at a later stage.
  
  
  CONCLUSIONS
  The authors' experience with octreotide LAR proved to be an efficacious means of controlling symptoms and stabilising disease without collateral effects. They conclude by affirming that octreotide LAR represents a valid therapeutic choice in the symptomatic treatment of neuroendocrine tumours.
authors.affiliation: Istituto di Chirurgia Sperimentale, V Divisione di Chirurgia Generale e Tecniche Speciali Chirurgiche, Seconda Università degli Studi, Naples, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Sperlongano
authors.forename: M
authors.initials: M
authors.lastname: De Falco
authors.forename: D
authors.initials: D
authors.lastname: Pisaniello
authors.forename: D
authors.initials: D
authors.lastname: Parmeggiani
authors.forename: U
authors.initials: U
authors.lastname: Parmeggiani
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D015282:Octreotide / Q000627:therapeutic use*; D010257:Paraneoplastic Syndromes / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000627:therapeutic use*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D013004:Somatostatin; D015282:Octreotide
vernacular_title: Efficacia degli analoghi della somatostatina nel trattamento dei tumori neuroendocrini e delle sindromi paraneoplastiche.