Synthesis and analytical evaluation by voltammetric studies of some new indole-3-propionamide derivatives.
Some biologically important and melatonin-related indole-3-propionamide derivatives were synthesized. The compounds synthesized were analyzed and characterized first by NMR and mass spectrometry and then investigated by analytical voltammetric techniques. Based on this study a simple, rapid and sensitive voltammetric method was developed for the determination of the indole derivatives that are readily oxidized at the carbon-based electrodes. The oxidative behavior of the indole derivatives was studied as a function of pH at a glassy carbon electrode. The characteristics of the corresponding electrode reaction were discussed.
Süzen
S
S
Department of Pharmaceutical Chemistry, Faculty of Pharmacy (Eczacilik), Ankara University, Tandoğan, Turkey. sibel@pharmacy.ankara.edu.tr
Ateş-Alagöz
Z
Z
Demircigil
B T
BT
Ozkan
S A
SA
D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry
D000577:Amides; D007211:Indoles