title: Invasive Salmonella virchow infection in childhood.
abstract: Salmonella virchow is generally considered to be one of the less invasive non-typhoidal Salmonellae species; however, several invasive cases have previously been reported. We report 3 cases of otherwise healthy children with S. virchow bacteraemia, monoarthritis and prevertebral abscess, only 1 of whom had previously had gastroenteritis. All 3 children responded to antibiotic regimens consisting of cefotaxime for 10 d, ceftriaxone for 3 weeks and ceftriaxone plus clindamycin for 4 weeks, respectively. In conclusion, S. virchow may be a more invasive serotype in immunocompetent children and present with a wider spectrum of manifestations than considered previously.
authors.affiliation: Department of Paediatrics, University of Crete, Heraklion, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Bitsori
authors.forename: E
authors.initials: E
authors.lastname: Galanakis
authors.forename: S
authors.initials: S
authors.lastname: Maraki
authors.forename: M
authors.initials: M
authors.lastname: Raissaki
authors.forename: E
authors.initials: E
authors.lastname: Velivassakis
authors.forename: S
authors.initials: S
authors.lastname: Sbyrakis
mesh_terms: D002439:Cefotaxime / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002981:Clindamycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008297:Male; D012475:Salmonella / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000175:diagnosis* / Q000188:drug therapy*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D002511:Cephalosporins; D002981:Clindamycin; D002443:Ceftriaxone; D002439:Cefotaxime