title: Trypanosoma evansi experimental infection in the South American coati (Nasua nasua): clinical, parasitological and humoral immune response.
abstract: The course of Trypanosoma evansi infection in coatis (Carnivora, Procionidae) was followed for 262 days. Parasites were detected in all infected animals from day 2 post infection until the end of the study. No correlation between temperature and parasitemia was observed. Animals of the infected group demonstrated depression, weakness, lethargy and pale mucous membranes. Indirect fluorescent antibody tests detected anti-T. evansi antibodies within 7 to 14 days post infection and showed high levels until the end of the experimental period. The persistent parasitemia in coati and their relative tolerance to clinical signs suggested that this species develops a chronic disease and plays an important role in the epidemiology of trypanosomosis due to T. evansi in enzootic regions.
authors.affiliation: Via de acesso Prof. Paulo Donato Castellane, s/n 14.884.900, /SP, Jaboticabal, Brazil.
authors.forename: H M
authors.initials: HM
authors.lastname: Herrera
authors.forename: L P
authors.initials: LP
authors.lastname: Aquino
authors.forename: R F
authors.initials: RF
authors.lastname: Menezes
authors.forename: L C
authors.initials: LC
authors.lastname: Marques
authors.forename: M A
authors.initials: MA
authors.lastname: Moraes
authors.forename: K
authors.initials: K
authors.lastname: Werther
authors.forename: R Z
authors.initials: RZ
authors.lastname: Machado
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000096:biosynthesis* / Q000097:blood; D002335:Carnivora / Q000469:parasitology*; D002353:Carrier State / Q000276:immunology / Q000469:parasitology / Q000662:veterinary; D002908:Chronic Disease; D004197:Disease Reservoirs / Q000662:veterinary; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D018512:Parasitemia / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*; D013997:Time Factors; D014345:Trypanosoma; D014352:Trypanosomiasis / Q000276:immunology / Q000469:parasitology / Q000662:veterinary*
chemical_list: D000913:Antibodies, Protozoan