title: Sentinel lymph node biopsy for breast cancer.
abstract: Sentinel lymph node biopsy (SLNB) is an emerging surgical technique to improve lymph node staging for breast cancer. Despite the rapid development of this technique, there remain aspects of SLNB that need to be further defined to provide a standardized approach. Variables, including patient selection, technical details for the performance of SLNB, extent of pathologic evaluation of the sentinel lymph node, and the impact of micrometastases, are areas of controversy. This paper reviews the controversies and discusses available data as well as personal experience and opinion.
authors.affiliation: Department of Surgery, Division of Surgical Oncology, University of California, Davis Cancer Center, 4501 X Street, Sacramento, CA 95817, USA. richard.bold@ucdmc.ucdavis.edu
authors.forename: R J
authors.initials: RJ
authors.lastname: Bold
authors.forename: M
authors.initials: M
authors.lastname: Schlieman
authors.forename: B N
authors.initials: BN
authors.lastname: Fahy
mesh_terms: D000368:Aged; D001365:Axilla; D015706:Bibliometrics; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000556:secondary / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D004396:Coloring Agents; D000075202:Contraindications; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects; D008207:Lymphatic Metastasis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008209:Lymphedema / Q000209:etiology / Q000517:prevention & control; D008408:Mastectomy; D008875:Middle Aged; D009367:Neoplasm Staging; D010348:Patient Care Team; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D021701:Sentinel Lymph Node Biopsy / Q000379:methods / Q000706:statistics & numerical data
chemical_list: D004396:Coloring Agents; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; C025484:iso-sulfan blue