Parenteral infusion of a lactating woman with intralipid: changes in milk and plasma fatty acids.
A nursing woman afflicted with short bowel syndrome received parenteral infusions of Intralipid. In the morning following 2 nights of infusion, samples of milk and blood were taken; additional samples were taken the morning after 1 and 2 nights of no infusion. The fatty acid composition of these samples was determined by gas chromatography. The Intralipid infusion contained 51.5% linoleic acid (C18:2). The C18:2 content of the milk was highest (14%) after each infusion and dropped to about 10% on days 1 and 2. Inverse changes were seen in stearic acid (C18:0). The C18:2 content of the plasma showed little change, remaining at about 23%. These results provide further direct evidence that the composition of milk fatty acids can be influenced by changes in the composition of external sources of fatty acids to the lactating mother.
Jensen
R G
RG
Department of Nutritional Sciences, University of Connecticut, Storrs 06269-4017, USA.
Lammi-Keefe
C J
CJ
MacBurney
M
M
Wijendran
V
V
D002849:Chromatography, Gas; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage*; D005227:Fatty Acids / Q000032:analysis* / Q000097:blood; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D007700:Kinetics; D007774:Lactation; D019787:Linoleic Acid / Q000032:analysis / Q000097:blood; D008895:Milk, Human / Q000737:chemistry*; D012778:Short Bowel Syndrome / Q000628:therapy; D013229:Stearic Acids / Q000032:analysis / Q000097:blood
D005217:Fat Emulsions, Intravenous; D005227:Fatty Acids; D013229:Stearic Acids; C031183:stearic acid; D019787:Linoleic Acid