title: How to calculate lead concentration and concentration uncertainty in XRF in vivo bone lead analysis.
abstract: The authors provide a substantial correction for calculating estimates of lead concentration and uncertainty for in vivo X-ray fluorescent bone analysis with Cd-109 source. Based on general principles, they provide mathematical techniques for propagation of uncertainties in XRF analysis. They give additional considerations for lowering the detection limit and improving spectral data quality.
authors.affiliation: Charles R. Drew University of Medicine & Science, Toxicology Research Laboratory, Environmental Research Center, Los Angeles, CA 90059, USA. vlkondra@cdrewu.edu
authors.forename: V S
authors.initials: VS
authors.lastname: Kondrashov
authors.forename: S J
authors.initials: SJ
authors.lastname: Rothenberg
mesh_terms: D001699:Biometry; D001842:Bone and Bones / Q000737:chemistry*; D003627:Data Interpretation, Statistical; D006801:Humans; D007854:Lead / Q000032:analysis*; D013052:Spectrometry, X-Ray Emission / Q000706:statistics & numerical data*
chemical_list: D007854:Lead