Effect of aging on multifocal oscillatory potentials.
Multifocal oscillatory potentials (m-OPs) are thought to reflect rod-cone interactions. We examined the effect of age on the topography of the m-OP responses out to an eccentricity of 30 deg. Fifty-eight normal subjects were studied, aged between 13.6 and 58.8 yr. The data show a linear decrease in amplitude and a linear increase in latency with age, which is significant for most potentials. The decrease is uniform over the retina. These results suggest that an age-related impairment is occurring at or before the inner retina.
Kurtenbach
Anne
A
Department of Pathophysiology of Vision and Neuro-ophthalmology, University Eye Hospital, Tübingen, Germany. anne.kurtenbach@uni-tuebingen.de
Weiss
Monika
M
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology*; D002648:Child; D004594:Electrophysiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009991:Oscillometry; D011930:Reaction Time; D017949:Retinal Cone Photoreceptor Cells / Q000502:physiology*; D017948:Retinal Rod Photoreceptor Cells / Q000502:physiology*