title: A computational study of the hemodynamics after "edge-to-edge" mitral valve repair.
abstract: Edge-to-edge mitral valve repair consists in suturing the free edge of the leaflets to re-establish coaptation in prolapsing valves. The leaflets are frequently sutured at the middle and a double orifice valve is created. In order to study the hemodynamic implications, a parametric model of the left heart has been developed. Different valve areas and shapes have been investigated. Results show that the simplified Bernoulli formula provides a good estimation of the pressure drop and that the pressure drop may be predicted on the basis of the pre-operative geometric and hemodynamics data by means of customized models.
authors.affiliation: Department of Bioengineering, Politecnico di Milano and CeBITeC, IRCCS San Raffaele and Politecnico di Milano, Milan, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Redaelli
authors.forename: G
authors.initials: G
authors.lastname: Guadagni
authors.forename: R
authors.initials: R
authors.lastname: Fumero
authors.forename: F
authors.initials: F
authors.lastname: Maisano
authors.forename: O
authors.initials: O
authors.lastname: Alfieri
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure; D003198:Computer Simulation; D020342:Finite Element Analysis; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D008943:Mitral Valve / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D008945:Mitral Valve Prolapse / Q000503:physiopathology* / Q000601:surgery*; D008955:Models, Cardiovascular