Two new 2'-oxygenated flavones from Andrographis elongata.
Two new 2'-oxygenated flavones, 5,2',6'-trihydroxy-7-methoxyflavone (3) and skullcapflavone I 2'-O-beta-D-(4"-E-cinnamyl) glucopyranoside (5), together with three known flavones, 7-O-methylwogonin (1), skullcapflavone I (2) and skullcapflavone I 2'-O-beta-D-glucopyranoside (4) were isolated from the whole plant of Andrographis elongata, and the structures were elucidated by FAB-MS and one- and two-dimensional (1D- and 2D)-NMR spectral studies including 1H-1H correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond connectivity (HMBC) and rotating frame Overhauser enhancement spectroscopy (ROESY) experiments, and chemical studies.
Jayakrishna
G
G
Department of Chemistry, Sri Venkateswara University, Tirupati, India.
Harikishore
P
P
Rao
C V
CV
Gunasekar
D
D
Blond
A
A
Bodo
B
B
D027901:Acanthaceae / Q000737:chemistry*; D000107:Acetylation; D003890:Desiccation; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
C454667:5,2',6'-trihydroxy-7-methoxyflavone; D005419:Flavonoids; D005960:Glucosides; D010936:Plant Extracts; C454668:skullcapflavone I 2'-O-(4''-cinnamyl)glucopyranoside