The first atisane diterpenoids from a liverwort: polyols from Lepidolaena clavigera.
Two new diterpenoids were isolated from the New Zealand liverwort Lepidolaena clavigera. Spectroscopic studies identified the structures as atisanes 1 and 2, with an unprecedented level of oxygenation. This is the first report of the atisane skeleton from a liverwort. Compound 2 showed cytotoxic and insecticidal activity. [structure: see text]
Perry
N B
NB
Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd., Department of Chemistry, University of Otago, Box 56, Dunedin, New Zealand. perryn@crop.cri.nz
Burgess
E J
EJ
Baek
S H
SH
Weavers
R T
RT
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013058:Mass Spectrometry; D008958:Models, Molecular; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry*
D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D007306:Insecticides