UGT1A1 polymorphism predicts irinotecan toxicity: evolving proof.
Mani
S
S
Medicine/Oncology, Weiler/AECOM Room 2S-63 1825 Eastchester Road Bronx, NY 10461, USA. smani@montefiore.org
D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000378:metabolism; D002166:Camptothecin / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000378:metabolism; D020719:Glucuronides / Q000378:metabolism; D014453:Glucuronosyltransferase / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D000077146:Irinotecan; D011110:Polymorphism, Genetic; D000099148:UGT1A1 Enzyme
D000972:Antineoplastic Agents, Phytogenic; D002166:Camptothecin; D020719:Glucuronides; D014453:Glucuronosyltransferase; D000077146:Irinotecan; D000099148:UGT1A1 Enzyme