title: [Inhalation sedation with nitrous oxide in dental extraction].
abstract: OBJECTIVE
  To study the advantages of nitrous oxide sedation in teeth extraction.
  
  
  METHODS
  112 patients were randomly allocated to four groups: 1) 60 mmol/L nitrous oxide, 2) 60 mmol/L nitrous oxide with estazolam, 3) 40 mmol/L nitrous oxide, 4) 40 mmol/L nitrous oxide with estazolam. The nitrous oxide was used for conscious sedation as an adjunct to local anaesthesia. 53 patients of control group underwent dental extraction with local anaesthesia only.
  
  
  RESULTS
  The postoperative MDAS scores of experimental group decreased and was significantly superior to control group (P < 0.01). The patients of experimental group showed a certain levels of sedation and partial amnesia. 97 of the 112 patients (86.62%) preferred inhalation sedation with nitrous oxide. There was no difference between the anxiolytic effects, sedative effects, amnestic effects of the four groups (P > 0.05). Estazolam as preoperative medieation did not show obvious coeffect with nitrous oxide.
  
  
  CONCLUSIONS
  Inhalation sedation with nitrous oxide can provide effects of goodquality antianxiery, sadation, amnesia in dental extraction.
authors.affiliation: Department of Stomatology, Beijing Tongren Hospital, Beijing 100730.
authors.forename: Y
authors.initials: Y
authors.lastname: Sun
authors.forename: D
authors.initials: D
authors.lastname: Qi
authors.forename: B
authors.initials: B
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D000766:Anesthesia, Dental; D018685:Anesthetics, Inhalation / Q000494:pharmacology*; D006801:Humans; D008875:Middle Aged; D009609:Nitrous Oxide / Q000494:pharmacology*; D014081:Tooth Extraction
chemical_list: D018685:Anesthetics, Inhalation; D009609:Nitrous Oxide