Mycobacterium doricum sp. nov.
A novel mycobacterial species is described in this study. The strain was isolated from the cerebrospinal fluid of a severely immunocompromised AIDS patient. It was scotochromogenic and slow-growing. Characteristic features for its differentiation from other mycobacteria are its lipid pattern and the unique gene sequences within the hypervariable regions of the 16S rDNA. The strain shows susceptibility to current antimycobacterial drugs. The pathogenicity of the novel mycobacterium and its clinical significance are not certain, as the neurological symptoms of the patient could also be due to concomitant infection with Cryptococcus neoformans. The name Mycobacterium doricum sp. nov. is proposed for the novel mycobacterium; the type strain is strain FI-13295T (= DSM 44339T = CIP 106867T).
Tortoli
E
E
Piersimoni
C
C
Kroppenstedt
R M
RM
Montoya-Burgos
J I
JI
Reischl
U
U
Giacometti
A
A
Emler
S
S
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D001483:Base Sequence; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D004275:DNA, Ribosomal / Q000235:genetics; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D009161:Mycobacterium / Q000737:chemistry / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D009164:Mycobacterium Infections / Q000382:microbiology*; D009171:Mycolic Acids / Q000032:analysis; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
D004275:DNA, Ribosomal; D005227:Fatty Acids; D009171:Mycolic Acids; D012336:RNA, Ribosomal, 16S