[Cancer procoagulant activity in cases of esophageal, stomach and colorectal cancer considering progression degree and histological type of cancer].
The cancer procoagulant activity has been evaluated in homogenates of esophagal, stomach and colorectal cancer tissues and in the blood serum of patients with these neoplasms's. Activity of CP was significantly higher in examined material than in control. The correlation between CP activity and progression degree as well as histological type was affirmed. The higher activity of CP in homogenates as well as in serum was observed in cases with higher degree of clinical progression and smaller activity of this enzyme corresponded with lower degree of the cancer progression. The highest activity of CP was observed in the cases of adenocarcinoma whereas the lowest in cases of squamous cell carcinoma. Higher activity of CP in homogenates of examined tissues correlated with higher activity of this enzyme in the serum. Activity of CP depended on the tissue localisation of the cancer and the highest was in the cases of stomach cancers whereas the lowest was in the cases of esophagal cancer.
Kozuszko
B
B
Białostocki Ośrodek Onkologiczny, Akademia Medyczna w Białymstoku.
Skrzydlewski
Z
Z
Sulkowska
M
M
Snarska
J
J
Kozłowski
M
M
Skrzydlewska
E
E
Zalewski
B
B
D000230:Adenocarcinoma / Q000097:blood* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000097:blood* / Q000473:pathology; D015179:Colorectal Neoplasms / Q000097:blood* / Q000473:pathology; D003546:Cysteine Endopeptidases / Q000097:blood*; D004938:Esophageal Neoplasms / Q000097:blood* / Q000473:pathology; D006801:Humans; D009363:Neoplasm Proteins / Q000097:blood*; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000097:blood* / Q000473:pathology
D009363:Neoplasm Proteins; D003546:Cysteine Endopeptidases; C030910:cancer procoagulant
Aktywność prokoagulanta nowotworowego w przypadkach raka przełyku, zoładka i jelita grubego z uwzglednieniem stopnia klinicznego zaawansowania i typu histologicznego nowotworu.