The ionic mechanisms of conduction in cardiac tissue.
Computer simulations are used to characterize conduction of the cardiac action potential under the following conditions: 1. Acute myocardial ischemia, 2. Reduced membrane excitability, 3. Reduced intercellular coupling, and 4. Propagation through inhomogeneous tissue structures.
Rudy
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Cardiac Bioelectricity Research and Training Center (CBRTC), Case Western Reserve University, Cleveland, OH 44106-7207, USA. yxr@po.cwru.edu
D000200:Action Potentials; D003198:Computer Simulation; D017629:Gap Junctions / Q000502:physiology; D006329:Heart Conduction System / Q000502:physiology*; D006801:Humans; D007473:Ion Channels / Q000502:physiology
D007473:Ion Channels