Ovarian capillary hemangioma and stromal luteinization: a case study with hormonal receptor evaluation.
BACKGROUND
Ovarian hemangiomas are rare tumors, most of them asymptomatic, and of the cavernous type. Six of the reported cases were accompanied by stromal luteinization. There is a debate whether these luteinized cells promote the growth of the vascular lesion or just represent a stromal reaction.


METHODS
A 71-year-old female was incidentally found to have a small capillary hemangioma in her left ovary, surrounded by a rim of luteinized stromal cells. Immunohistochemical investigation revealed the presence of estrogen and progesterone receptors in the endothelial cells of the lesion.


CONCLUSIONS
Our histological and immunohistochemical findings, as well as data from the literature, support the view that at least some vascular lesions may result from hormonal stimulation.
Miliaras
D
D
Department of Pathology, General Clinic of Thessaloniki, Aristotelian University, Thessaloniki, Greece.
Papaemmanouil
S
S
Blatzas
G
G
D000230:Adenocarcinoma / Q000601:surgery; D000368:Aged; D003110:Colonic Neoplasms / Q000601:surgery; D005260:Female; D018324:Hemangioma, Capillary / Q000378:metabolism* / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008184:Luteal Cells; D009378:Neoplasms, Multiple Primary; D010051:Ovarian Neoplasms / Q000378:metabolism* / Q000473:pathology*; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone