title: The connectivity index 25 years after.
abstract: We review the developments following introduction of the connectivity indices as molecular descriptors in multiple linear regression analysis (MLRA) for structure-property-activity studies. We end the review with discussion of results obtained with applications of the variable connectivity index. A comparison is made between some results obtained with the traditional topological indices and the variable connectivity index.
authors.affiliation: Department of Mathematics and Computer Science, Drake University, Des Moines, IA 50014, USA.
authors.forename: M
authors.initials: M
authors.lastname: Randić
mesh_terms: D016014:Linear Models; D015394:Molecular Structure; D015999:Multivariate Analysis; D013329:Structure-Activity Relationship