Disinfectant activity against different morphological forms of Helicobacter pylori: first results.
The pathogenic bacterium Helicobacter pylori, which has infected more than one-half of the world's human population, exists in two morphological forms; the viable helical form and the disputed viable-but-not-culturable coccoid form. Infection by the helical form proceeds through the oral-oral route, while that by the coccoid form, if possible at all, is by the faecal-oral and/or the oral-oral route. The present pilot study addresses the question of disinfectant efficacy against both forms of the bacterium.
Gebel
J
J
Institute of Hygiene, University of Bonn, Germany. gebel@meb.uni-bonn.de
Vacata
V
V
Sigler
K
K
Pietsch
H
H
Rechenburg
A
A
Exner
M
M
Kistemann
T
T
D002626:Chemistry, Pharmaceutical; D004202:Disinfectants / Q000737:chemistry / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D004866:Equipment Contamination / Q000517:prevention & control*; D005976:Glutaral / Q000737:chemistry / Q000494:pharmacology*; D017408:Guidelines as Topic; D016480:Helicobacter pylori / Q000145:classification / Q000187:drug effects* / Q000472:pathogenicity; D006801:Humans; D017053:Infection Control / Q000379:methods* / Q000592:standards; D010865:Pilot Projects
D004202:Disinfectants; D005976:Glutaral