[Anti-inflammatory effect of dichlotazole].
Experiments on various animals showed that dichlotazole, a new triazole derivative, possesses a high antiinflammatory activity and low toxicity. The mechanism of the antiphlogistic effect of dichlotazol is due to its antagonism with respect to mediators of the inflammatory process and the ability of suppressing the increased permeability of capillaries.
Zakirov
A U
AU
Sultanov Research Institute of Pharmaceutical Chemistry, ul. F. Khodzhaeva 40, Tashkent, 700187 Uzbekistan.
Pulatov
Kh Kh
KhKh
Ismatov
D N
DN
Azizov
U M
UM
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use* / Q000633:toxicity; D001169:Arthritis, Experimental / Q000188:drug therapy; D002056:Burns / Q000188:drug therapy; D010538:Peritonitis / Q000188:drug therapy; D051381:Rats; D014230:Triazoles / Q000627:therapeutic use* / Q000633:toxicity
C443659:1-phenyl-(4,4-bis(2,4-dichlorobenzoyloxymethyl)-1,2,3-triazole); D000894:Anti-Inflammatory Agents, Non-Steroidal; D014230:Triazoles
Izuchenie protivovospalitel'nykh svoĭstv dikhlotazola.