[Study on chitosan-gelatin/hydroxyapatite composite scaffolds--preparation and morphology].
OBJECTIVE
To prepare chitosan-gelatin/hydroxyapatite (CS-Gel/HA) composite scaffolds, and to investigate the influence of components and preparing conditions to their micromorphology.


METHODS
The CS-Gel/HA composite scaffolds were prepared by phase-separation method. Micromorphology and porosity were detected by using scanning electron microscope and liquid displacement method respectively.


RESULTS
Porous CS-Gel/HA composite scaffolds could be prepared by phase-separation method, and their density and porosity could be controlled by adjusting components and quenching temperature.


CONCLUSIONS
The study suggests the feasibility of using CS-Gel/HA composite scaffolds for the transplantation of autogenous osteoblasts to regenerate bone tissue.
Zhao
F
F
Research Institute of Polymeric Materials, Tianjin University, Tianjin, P.R. China 300072.
Yin
Y J
YJ
Song
X F
XF
D001672:Biocompatible Materials; D002686:Chitin / Q000031:analogs & derivatives*; D048271:Chitosan; D005780:Gelatin; D006882:Hydroxyapatites; D023822:Tissue Engineering
D001672:Biocompatible Materials; D006882:Hydroxyapatites; D002686:Chitin; D005780:Gelatin; D048271:Chitosan