Thiopurine methyl transferase: activity and genotyping in patients with acute lymphoblastic leukemia.
Brouwer
C
C
Center for Pediatric Oncology S.E. Netherlands, University Medical Center St Radboud, Department of Pediatrics, Nijmegen.
Keizer-Garritsen
J J
JJ
Lambooy
L H
LH
Ament
K
K
Ter Riet
P G
PG
De Abreu
R A
RA
Bökkerink
J P
JP
Van Wering
E R
ER
Van Der Does-Van Den Berg
A
A
Veerman
A J
AJ
Trijbels
J P
JP
D000483:Alleles; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D002648:Child; D005260:Female; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D008297:Male; D015122:Mercaptopurine / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D008780:Methyltransferases / Q000235:genetics* / Q000378:metabolism*; D009154:Mutation; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000201:enzymology* / Q000235:genetics
D000964:Antimetabolites, Antineoplastic; D015122:Mercaptopurine; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D008727:Methotrexate