title: [Pathologic diagnosis of usual interstitial pneumonia].
abstract: OBJECTIVE
  To discuss pathologic differential diagnosis between UIP and the other types of IPF.
  
  
  METHODS
  The slides (routine and histochemical stain) of 4 autopsy cases of UIP were reviewed.
  
  
  RESULTS
  The most significant characteristic of UIP is that the interstial changes show temporal heterogeneity and variable distribution. The earlier stage of UIP shows an interstitial infiltrate of chronic inflammation cells and the progressive stage appears significant interstitial fibrosis. The honeycomb change and muscular cirrhosis are the characteristics of the end stage.
  
  
  CONCLUSIONS
  For clinical purpose, the distinction of UIP and the other types of IPF is of great significance because of marked differences in the prognosis and therapy.
authors.affiliation: Pathology Department, PUMC Hospital, PUMC, Beijing 100730, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Jiang
authors.forename: H
authors.initials: H
authors.lastname: Liu
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000473:pathology