[Recurrence, metastasis and complications of stage I and II endometrial neoplasms treated by different therapeutic modalities].
OBJECTIVE
To make an approach to the relationship between recurrence, metastasis and complication of stage I and II endometrial carcinoma treated by 4 different therapeutic modalities.


METHODS
To compare the rates of recurrence, metastasis and complication in 4 treatment groups (surgery, full-dose preoperative intracavitary irradiation, non-full dose preoperative intracavitary irradiation and radiation alone).


RESULTS
Recurrence and metastasis in surgery, full-dose preoperative intracavitary irradiation, non full-dose preoperative intracavitary and radiotherapy alone groups were 19.8%, 8.1%, 22.2% and 34.6%, respectively. The recurrent rates of vaginal stump were 6.2%, 1.6%, 11.1% and 11.5%, respectively. The rates of proctitis and cystitis in full dose preoperative intracavitary irradiation group were 3.2% and 3.2%, 2.8 and 0.0% in non-full dose preoperative intracavitay irradiation group, and 0.0% and 3.8% in radiotherapy alone group.


CONCLUSIONS
The rates of recurrence and metastasis in full-dose preoperative intracavitary irradiation group were the lowest compared with other groups and incidence of complication was also low. This therapeutic method is the optimal choice for the treatment of endometrial carcinoma with stage I and II.
Sun
J
J
Department of Gynecologic Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing Union Medical College, Beijing 100021, China.
Sheng
X
X
Zhou
C
C
D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011878:Radiotherapy / Q000009:adverse effects; D015996:Survival Rate