Fetal intracranial hemorrhage due to antenatal low dose aspirin intake.
Antenatal intake of low dose aspirin is advised for prevention of pregnancy induced hypertension, intrauterine growth retardation and pre-term labour. Aspirin has an anticoagulant effect due to its action on Cyclo-oxygenase and vitamin K dependent coagulation factors. It can readily cross the placental barrier and be a potential cause for bleeding tendency in the fetus. Fetal intracranial hemorrhage, following low dose aspirin administration in a mother and subsequent effect after delivery is being reported.
Sasidharan
C K
CK
Division of Neonatology, Dept. of Pediatrics, IMCH, Medical College, Calicut, Kerala, India.
Kutty
P M
PM
Ajithkumar
Sajith
N
N
D000014:Abnormalities, Drug-Induced / Q000000981:diagnostic imaging*; D000328:Adult; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects*; D002585:Cesarean Section; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D020300:Intracranial Hemorrhages / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008297:Male; D008431:Maternal-Fetal Exchange / Q000187:drug effects*; D011247:Pregnancy; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed; D016216:Ultrasonography, Prenatal
D001241:Aspirin