Fat-soluble vitamin status is not affected by diacylglycerol consumption.
OBJECTIVE
The objective of this study was to examine the effect of dietary diacylglycerol (DAG) on the bioavailability of fat-soluble vitamins in comparison with triacylglycerol (TAG).


METHODS
We conducted a long-term administration test of DAG and TAG in 27 healthy men aged 27-47 years. After measuring baseline values, subjects were randomized into two groups, one group (n = 15) was given DAG and the other (n = 12) was given TAG. Subjects ingested 20 g of DAG or TAG either in mayonnaise or an emulsion drink of their own choice at meals once a day for 12 weeks. At 4, 8 and 12 weeks, fasting blood samples were drawn and serum levels of vitamin A, E, and D were measured.


RESULTS
There were no significant changes in vitamin A levels throughout the study period. Compared to the initial values (using a Student's t test for paired values), significant differences of vitamin E and D were seen at some points during the experiment. According to a two-way repeated measures analysis of variance, however, DAG and TAG (lipid) and time had no effect on fat-soluble vitamin levels.


CONCLUSIONS
Our results indicate that DAG does not affect the absorption of the fat-soluble vitamins in diets.
Watanabe
H
H
Biological Science Laboratories, Kao Corporation, 2606, Akabane, Ichikai-machi, Haga-gun, Tochigi 321-3497, Japan. 306945@kastanet.kao.co.jp
Onizawa
K
K
Naito
S
S
Taguchi
H
H
Goto
N
N
Nagao
T
T
Matsuo
N
N
Tokimitsu
I
I
Yasukawa
T
T
Tsushima
R
R
Shimasaki
H
H
Itakura
H
H
D000328:Adult; D000704:Analysis of Variance; D001682:Biological Availability; D004075:Diglycerides / Q000008:administration & dosage*; D004311:Double-Blind Method; D006801:Humans; D007408:Intestinal Absorption; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D014280:Triglycerides / Q000008:administration & dosage*; D014801:Vitamin A / Q000097:blood / Q000493:pharmacokinetics*; D014807:Vitamin D / Q000097:blood / Q000493:pharmacokinetics*; D014810:Vitamin E / Q000097:blood / Q000493:pharmacokinetics*
D004075:Diglycerides; D014280:Triglycerides; D014801:Vitamin A; D014807:Vitamin D; D014810:Vitamin E