Anti-stress and anti-fatigue effects of fermented rice bran.
The anti-stress and anti-fatigue effects on rats and mice of a hot water extract of rice bran fermented with Saccharomyces cerevisae IFO 2346 were investigated. Oral administration (1 g/kg/day) of the hot water extract of fermented rice bran (FRB) inhibited major changes in the weight of the adrenal, thymus, spleen and thyroid, showing an anti-stress effect. The hot water extract of FRB also inhibited increases in the GPT and LDH activity, cholesterol and glucose in the serum. The administration (1 g/kg/day) for 2 weeks significantly prolonged the swimming time, resulting in an increase in the anti-fatigue effect. It is considered from these results that FRB had anti-stress and anti-fatigue effects.
Kim
K M
KM
School of Food Biotechnology, Woosong University, Daejeon, Korea.
Yu
K W
KW
Kang
D H
DH
Koh
J H
JH
Hong
B S
BS
Suh
H J
HJ
D000276:Adjuvants, Immunologic / Q000378:metabolism / Q000494:pharmacology; D019883:Alkyl and Aryl Transferases / Q000097:blood; D000818:Animals; D000880:Anthraquinones / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D004187:Disaccharides / Q000097:blood; D005221:Fatigue / Q000517:prevention & control*; D005936:Glucans / Q000378:metabolism / Q000494:pharmacology*; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009929:Organ Size; D051381:Rats; D017207:Rats, Sprague-Dawley; D013312:Stress, Physiological / Q000517:prevention & control*; D013550:Swimming; D017855:Transferases (Other Substituted Phosphate Groups) / Q000097:blood
D000276:Adjuvants, Immunologic; D000880:Anthraquinones; D001786:Blood Glucose; D004187:Disaccharides; D005936:Glucans; C065495:rice bran saccharide; C064333:ruberythric acid; D002784:Cholesterol; D007770:L-Lactate Dehydrogenase; D019883:Alkyl and Aryl Transferases; C112459:geranylpyrophosphate olivetolate geranyltransferase; D017855:Transferases (Other Substituted Phosphate Groups); C106504:UDP-GlcNAc-undecaprenyl phosphate N-acetylglucosaminyl 1-phosphate transferase