title: A new predictor of improvement in regional left ventricular function assessed by ST/HR slope derived from ST elevation on exercise testing in patients with healed myocardial infarction.
abstract: This study evaluates the clinical usefulness of ST/HR slope derived from ST elevation on exercise to predict the improvement in regional wall motion following coronary revascularization in patients with healed myocardial infarction. We studied 58 patients with a diseased, infarct-related and single-vessel coronary artery. The decline calculated from the final 12 data points relating ST-segment elevation to heart rate during exercise were derived (ST/HR slope). Hypokinesis in the infarcted region was assessed by the centerline method and expressed in terms of standard deviations (SD/chord). The increase more than 30% of the SD/chord, which was defined as the improvement in regional wall motion, was seen in 23 of the 30 patients with a ST/HR slope of > or = 5.0 (microV/bpm), and in 4 of the 28 patients with a ST/HR slope <5.0 (microV/bpm) (P <.0001). Thus, a ST/HR slope derived from ST elevation on exercise identifies subgroups of patients who show a good recovery of regional wall motion.
authors.affiliation: First Department of Internal Medicine, Kagoshima University, Sakuagaoka, Kagoshima, Japan.
authors.forename: Fumio
authors.initials: F
authors.lastname: Nakano
authors.forename: Shuichi
authors.initials: S
authors.lastname: Hamasaki
authors.forename: Minoru
authors.initials: M
authors.lastname: Tahara
authors.forename: Koichi
authors.initials: K
authors.lastname: Kihara
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kamekou
authors.forename: Masanori
authors.initials: M
authors.lastname: Tsurugida
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshitama
authors.forename: Sanemasa
authors.initials: S
authors.lastname: Ishida
authors.forename: Akiko
authors.initials: A
authors.lastname: Yoshikawa
authors.forename: Tetsurou
authors.initials: T
authors.lastname: Kataoka
authors.forename: Keishi
authors.initials: K
authors.lastname: Saihara
authors.forename: Shinichi
authors.initials: S
authors.lastname: Minagoe
authors.forename: Chuwa
authors.initials: C
authors.lastname: Tei
mesh_terms: D000328:Adult; D000368:Aged; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013793:Thallium; D016277:Ventricular Function, Left / Q000502:physiology*
chemical_list: D013793:Thallium