title: Population-based survey of antimicrobial susceptibility and serotype distribution of Streptococcus pneumoniae from meningitis patients in Salvador, Brazil.
abstract: Penicillin-nonsusceptible strains were isolated from 15% of 303 individuals with pneumococcal meningitis identified during a 4-year surveillance study in Salvador, Brazil. The estimated rate of coverage of the seven-valent conjugate vaccine was 74% among patients <5 years of age and 94% among those infected with nonsusceptible isolates, indicating that the use of conjugate vaccines may be an approach to the control of emerging penicillin resistance in Brazil.
authors.affiliation: Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Brazil.
authors.forename: Joice Neves
authors.initials: JN
authors.lastname: Reis
authors.forename: Soraia Machado
authors.initials: SM
authors.lastname: Cordeiro
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Coppola
authors.forename: Kátia
authors.initials: K
authors.lastname: Salgado
authors.forename: Maria G S
authors.initials: MG
authors.lastname: Carvalho
authors.forename: Lúcia M
authors.initials: LM
authors.lastname: Teixeira
authors.forename: Terry A
authors.initials: TA
authors.lastname: Thompson
authors.forename: Richard R
authors.initials: RR
authors.lastname: Facklam
authors.forename: Mitermayer G
authors.initials: MG
authors.lastname: Reis
authors.forename: Albert I
authors.initials: AI
authors.lastname: Ko
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008586:Meningitis, Pneumococcal / Q000453:epidemiology* / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D011159:Population Surveillance; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents