[Effect of the water deprivation during pregnancy on the water-salt tissue composition and kidney function in the rat offspring of the first and second generation].
Rats were subjected to intermittent water restriction from the 1st day of pregnancy until delivery. Water, sodium, and potassium contents in the liver, brain, skeletal muscles, heart, kidneys, and subcutaneous fat tissue were determined in the litter. Water and sodium contents in 30-day old rats of the 1st and 2nd generation were found to be comparable to the control values. Water loading resulted in weaker diuretic responses in the former rats as compared with the control. No differences in the renal response were revealed in adult rats.
Kushner
S R
SR
Pedagogical University, Novosibirk, 630126, Russia.
Iglina
N G
NG
Aĭzman
R I
RI
D000818:Animals; D000831:Animals, Newborn; D004231:Diuresis; D005260:Female; D007668:Kidney / Q000502:physiology*; D007677:Kidney Function Tests; D009928:Organ Specificity; D011188:Potassium / Q000032:analysis; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000032:analysis; D014867:Water / Q000032:analysis; D014868:Water Deprivation; D014882:Water-Electrolyte Balance
D014867:Water; D012964:Sodium; D011188:Potassium
Vliianie vodnoĭ deprivatsii v period beremennosti krys na vodno-solevoĭ sostav tkaneĭ i funktsii pochek potomstva pervogo i vtorogo pokoleniĭ.