title: Evaluation of diagnostic availability of continuous ANP assay and LA/AO ratio in left heart insufficient dogs.
abstract: Left atrial/aorta ratio (LA/AO) by echocardiography and the plasma level of atrial natriuretic peptide (ANP) were measured in 32 dogs with left heart insufficiency. There was a significant correlation between plasma ANP concentration and LA/AO (r=0.66, p<0.001). The authors obtained the result that the degree of expansion of the left atrial diameter seemed to have a close relationship with plasma ANP concentration. Plasma ANP concentration decreased when the clinical signs of the patients improved. However, the LA/AO ratio after treatment did not decrease. From these findings, we concluded that plasma ANP concentration has the possibility to become a significant index in the diagnosis and prognosis of heart disease in dogs.
authors.affiliation: Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Koie
authors.forename: K
authors.initials: K
authors.lastname: Kanayama
authors.forename: T
authors.initials: T
authors.lastname: Sakai
authors.forename: A
authors.initials: A
authors.lastname: Takeuchi
mesh_terms: D000818:Animals; D001011:Aorta / Q000000981:diagnostic imaging; D009320:Atrial Natriuretic Factor / Q000097:blood*; D004283:Dog Diseases / Q000097:blood* / Q000000981:diagnostic imaging*; D004285:Dogs; D004452:Echocardiography / Q000662:veterinary; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging*; D006331:Heart Diseases / Q000097:blood / Q000000981:diagnostic imaging / Q000662:veterinary*; D008297:Male; D013902:Radiography, Thoracic / Q000662:veterinary
chemical_list: D009320:Atrial Natriuretic Factor