title: [Fournier syndrome: multidisciplinary approach].
abstract: Fournier's gangrene, a form of necrotizing fasciitis, is an uncommon, fulminant, rapidly progressing subcutaneous infection of the scrotum and genito-perineal region, and may occur in all age groups. Most cases involve a mixed synergistic infection of aerobic and anaerobic bacteria, and occur as a result of one of this mechanisms: local trauma, extension from a perineal, periurethral or ischiorectal infection. It is associated with a high mortality rate. Predisposing factors included diabetes mellitus, steroids or chemotherapy, alcohol abuse, malignancy and radiation therapy. This disease requires prompt treatment: early diagnosis, antibiotic therapy, nutritional support, immediate extensive surgical debridement and hyperbaric oxygen therapy. The use of etherologue serum is a valuable adjunct in the therapy of Fournier's gangrene. We report a case of Fournier's syndrome treated with etherologue serum immuno-therapy, together with the conventional multidisciplinary approach. The postoperative course was uneventful and the patient was discharged on day 50 post intervention in good general conditions. The 3 years follow-up showed no recurrence of the disease. In conclusion we remark that the survival can be improved in patients with Fournier's gangrene by multidisciplinary approach.
authors.affiliation: Università degli Studi Magna Graecia Catanzaro Chirurgia Generale.
authors.forename: G
authors.initials: G
authors.lastname: Vescio
authors.forename: M
authors.initials: M
authors.lastname: Battaglia
authors.forename: L
authors.initials: L
authors.lastname: Sommella
authors.forename: G
authors.initials: G
authors.lastname: Gallelli
authors.forename: F
authors.initials: F
authors.lastname: Manzo
authors.forename: S F
authors.initials: SF
authors.lastname: Cristiano
authors.forename: A
authors.initials: A
authors.lastname: Valente
authors.forename: S
authors.initials: S
authors.lastname: Musella
mesh_terms: D003131:Combined Modality Therapy; D018934:Fournier Gangrene / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged
vernacular_title: Sindrome di Fournier: approccio multidisciplinare.