title: Safety of steroid injections in the treatment of nasofrontal recess obstruction.
abstract: A retrospective review was undertaken to determine if steroid injection is a safe and effective intervention in the management of chronic nasofrontal recess obstruction. Seventy-four patients were identified who had undergone prior endoscopic sinus surgery and subsequently developed nasofrontal recess obstruction that was treated with injection of Kenalog 20 mg/mL (Bristol-Myers Squibb Co., Princeton, NJ) directly into the polyps or fibrosis. The study included 38 men and 36 women with a mean age of 45.4 years. These patients collectively underwent 687 injections, an average of 9.3 injections per patient. The indication was polyposis in 70 patients and fibrosis in 17 patients, with 13 sharing both indications. These patients also required 112 office procedures to maintain nasofrontal recess patency, an average of 1.5 procedures per patient. Three patients eventually required frontal sinus obliteration. The mean follow-up period from the initial injection was 50.1 months, and no complications were reported. Therefore, nasofrontal steroid injection appears to be safe and effective in the treatment of nasofrontal recess obstruction.
authors.affiliation: Department of Otolaryngology and Bronchoesophagology, Rush-Presbyterian-St Luke's Medical Center, Rush Medical College, Chicago, Illinois, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Dutton
authors.forename: R M
authors.initials: RM
authors.lastname: Bumsted
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D005626:Frontal Sinus / Q000473:pathology / Q000601:surgery; D015522:Frontal Sinusitis / Q000150:complications* / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000150:complications* / Q000188:drug therapy* / Q000601:surgery; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D013256:Steroids