[The isolation and drug susceptibility of penicillin resistant Streptococcus pneumoniae in Guangzhou].
OBJECTIVE
To investigate the isolation rate and drug susceptibility of PRSP in Guangzhou and in vitro antimicrobial activities of 8 antimicrobial agents against PRSP.


METHODS
MICs were tested by E-test.


RESULTS
Of 102 strains of Streptococcus pneumoniae, 12 strains were low-level resistant against penicillin (isolation rate 11.8%) and the antimicrobial activites of 5 drugs (augmentin, cefaclor, ceftriaxone, cefuraxime, ofloxaxin) against them were within their MICs, augmentin and ceftriaxone being the most powerful. They were resistant to azithromicin, oxacillin and penicillin.


CONCLUSIONS
The isolation rate of Penicillin resistant Streptococcus pneumoniae was not high in Guangzhou, but it may increase with the extensive use of antimicrobial agents, which deserves much attention.
Tang
Y
Y
Department of Respiratory Medicine, Third Affiliated Hospital of Sun Yatsen University of Medical Sciences, Guangzhou 510630.
Zhu
J
J
Zhang
K
K
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002681:China; D006801:Humans; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance / Q000502:physiology*; D013296:Streptococcus pneumoniae / Q000187:drug effects / Q000302:isolation & purification* / Q000502:physiology
D000900:Anti-Bacterial Agents