Rapid and versatile synthesis of functionalized polyhydroxylated fragments.
[reaction: see text] The condensation between a functionalized allylstannane and alpha-alkoxyaldehydes allows rapid access to complex and selectively protected trihydroxylated synthons. The stereocontrol of this process is strongly dependent upon the nature and the amount of the Lewis acid employed.
Leroy
Bernard
B
Université catholique de Louvain, Département de Chimie, Bâtiment Lavoisier, Place Louis Pasteur 1, B-1348 Louvain-la-Neuve, Belgium. marko@chim.ucl.ac.be
Markó
István E
IE
D000447:Aldehydes / Q000737:chemistry*; D000498:Allyl Compounds / Q000737:chemistry*; D006900:Hydroxylation; D007202:Indicators and Reagents; D008968:Molecular Conformation; D009947:Organotin Compounds / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D000498:Allyl Compounds; D007202:Indicators and Reagents; D009947:Organotin Compounds