[A randomized clinical study of preoperative chemotherapy for esophageal carcinoma].
OBJECTIVE
To evaluate the effect of preoperative chemotherapy on the prognosis of stage II or III patients with esophageal carcinoma.


METHODS
From February 1991 to June 1994, 50 patients with stage II, III esophageal carcinoma were treated with preoperative combination (CDDP) chemotherapy and compared with 50 patients received operation alone.


RESULTS
The 5-year survival rate of the operation group and preoperative chemotherapy group was 32% and 46%, respectively. The difference was statistically significant.


CONCLUSIONS
Preoperative chemotherapy improves survival of surgically treated esophageal cancer patients.
Wang
C
C
Shanxi Tumor Hospital, Taiyuan 030013, China.
Ding
T
T
Chang
L
L
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011379:Prognosis; D015996:Survival Rate; D016896:Treatment Outcome