Successful treatment of AIDS-related disseminated cutaneous sporotrichosis with itraconazole.
Sporotrichosis is a chronic granulomatous mycosis caused by a dimorphic fungus, Sporothrix schenckii. The most common manifestations of infection are lymphocutaneous and fixed-cutaneous types. In the case of immunosuppressed patients, and particularly in patients with acquired immune deficiency syndrome (AIDS), it occurs as disseminated cutaneous disease. This is a report of a 28-year-old male patient who presented with disseminated cutaneous and hematogenous sporotrichosis involving multiple ulcerative, nodular lesions in various body areas. Treatment consisted of 300 mg/d of itraconazole, which resulted in clinical and mycological cure.
Bonifaz
A
A
Dermatology Service and Mycology Department, Hospital General de México OD, Mexico City, Mexico. bonyalx@servidor.unam.mx
Peniche
A
A
Mercadillo
P
P
Saúl
A
A
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D013174:Sporotrichosis / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
D000935:Antifungal Agents; D017964:Itraconazole