[Comparative characterization of the antigenic composition of M. leprae and M. lufu].
The antigenic structure of M. leprae and M. lufu was comparatively studied for the first time. M. lufu was found to have M. leprae-specific protein with a molecular weight of 36 kDa. M. leprae and M. lufu were similar in their fractional composition of proteins and an antibody response to determinants with equal molecular weights in patients with different forms of leprosy and its varying severity. The findings may improve a diagnostic system in leprosy by using M. lufu antigens as an alternative.
Salamatina
O S
OS
Diachina
M N
MN
Iushchenko
A A
AA
Chernousova
L N
LN
Kalinina
O N
ON
Parshin
M P
MP
D000942:Antigens, Bacterial / Q000032:analysis*; D003470:Culture Media; D003622:Dapsone / Q000494:pharmacology; D004586:Electrophoresis; D006801:Humans; D015151:Immunoblotting; D007917:Leprostatic Agents / Q000494:pharmacology; D007918:Leprosy / Q000188:drug therapy / Q000382:microbiology*; D008970:Molecular Weight; D009161:Mycobacterium / Q000187:drug effects / Q000276:immunology* / Q000302:isolation & purification; D009166:Mycobacterium leprae / Q000187:drug effects / Q000276:immunology* / Q000302:isolation & purification
D000942:Antigens, Bacterial; D003470:Culture Media; D007917:Leprostatic Agents; D003622:Dapsone
Sravnitel'naia kharakteristika antigennogo sostava M. leprae i M.lufu.