title: Retroperitoneal haematoma after paracetamol increased anticoagulation.
abstract: Drugs containing paracetamol are widely used as analgesics but may result in increased anticoagulation in patients who take warfarin, the mechanism being unclear. Retroperitoneal haemorrhage is a serious and well described complication in patients who develop increased anticoagulation; this may result in a femoral neuropathy. Both conservative and surgical treatments have been advocated for this complication.
authors.affiliation: Accident and Emergency Department, St James's University Hospital, Leeds, UK. fandrews@liv.ac.uk
authors.forename: F J
authors.initials: FJ
authors.lastname: Andrews
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects*; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D004357:Drug Synergism; D005260:Female; D020428:Femoral Neuropathy / Q000209:etiology*; D006406:Hematoma / Q000139:chemically induced*; D006801:Humans; D019934:International Normalized Ratio; D008875:Middle Aged; D012187:Retroperitoneal Space; D014859:Warfarin / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen; D014859:Warfarin