Primary malignant lymphoma of the parotid gland report of three cases.
OBJECTIVE
To document the clinicopathologic features and treatment modalities of primary malignant parotid gland lymphoma, based on three cases diagnosed and treated at Oldchurch Hospital, Romford, UK.


METHODS
Three patients, two with stage II and one with stage IV disease, received primary treatment consisting of chemotherapy following surgical biopsy.


RESULTS
All three patients obtained rapid complete remission during their scheduled chemotherapy. One patient is alive without evidence of disease 12 months from the end of treatment. One patient, a frail, elderly gentleman, died due to massive pneumonia while in complete remission for two months. The third patient, who developed local recurrences in both parotid glands without transformation of his low-grade histology, achieved a second complete remission following chemo- and radiotherapy. All side effects were of a mild nature.


CONCLUSIONS
Malignant lymphoma of the parotid gland is a chemo- and radiosensitive disease.
Stein
M E
ME
Department of Clinical Oncology and Radiotherapy, Oldchurch Hospital, Romford, UK. m_stein@rambam.health.gov.il
Brunnel
A
A
Lewis
D
D
Zidan
J
J
Gershuny
A
A
D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000628:therapy*