[Neurochemical characteristics of the ventromedial hypothalamus and anti-aversive effects of anxiolytic agents in various anxiety models].
Neurochemical analysis using anxiosedative and anxioselective agents injected into the hypothalamus revealed that antiaversive action of camprione is only realised under conditions of domineering fear motivation whereas that of chlordiazepoxide, phenibut, indoter may also be realised under conditions of negative stressful zoo-social impacts mediated by serotonin.
Talalaenko
A N
AN
Gorky Medical University, Donetsk, 83003, Ilyich Ave., 16, Ukraine.
Pankrat'ev
D V
DV
Goncharenko
N V
NV
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000596:Amino Acids / Q000819:agonists / Q000037:antagonists & inhibitors / Q000494:pharmacology; D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001007:Anxiety / Q000209:etiology / Q000378:metabolism*; D001362:Avoidance Learning / Q000187:drug effects; D015306:Biogenic Monoamines / Q000819:agonists / Q000037:antagonists & inhibitors / Q000494:pharmacology; D002707:Chlordiazepoxide / Q000494:pharmacology; D065127:Dopamine D2 Receptor Antagonists; D018756:GABA Antagonists / Q000494:pharmacology; D006247:Harmine / Q000031:analogs & derivatives* / Q000494:pharmacology; D007033:Hypothalamus, Middle / Q000378:metabolism*; D008845:Microinjections; D010879:Piperazines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology; D051381:Rats; D011963:Receptors, GABA-A / Q000187:drug effects; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors; D018490:Serotonin Agents / Q000494:pharmacology; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000494:pharmacology
D000317:Adrenergic alpha-Antagonists; D000596:Amino Acids; D014151:Anti-Anxiety Agents; D015306:Biogenic Monoamines; D065127:Dopamine D2 Receptor Antagonists; D018756:GABA Antagonists; D010879:Piperazines; D011743:Pyrimidines; D011963:Receptors, GABA-A; D016194:Receptors, N-Methyl-D-Aspartate; D018490:Serotonin Agents; C082647:Kampirone; D006247:Harmine; D005680:gamma-Aminobutyric Acid; D002707:Chlordiazepoxide; C005010:harman; C008842:4-amino-3-phenylbutyric acid
Neĭrokhimicheskie osobennosti ventromedial'nogo gipotalamusa v realizatsii antiaversionnykh éffektov anksiolitikov na razlichnykh modeliakh trevogi.