Looking at soluble CD23 levels to predict lymphoma.
As we noted in our first article on lymphoma, there isn't any quick and simple test to diagnose or predict which PHAs will develop this cancer. Nor are there any symptoms that specifically occur from having lymphoma. To try to remedy the situation, researchers in Italy have been monitoring levels of the a protein called soluble CD23 (sCD23) in the blood and fluid surrounding the brain--cerebrospinal fluid (CSF). They have found higher-than-normal levels of sCD23 in the CSF of PHAs who have brain lymphoma.
D014408:Biomarkers, Tumor / Q000097:blood*; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000097:blood / Q000175:diagnosis*; D011237:Predictive Value of Tests; D017455:Receptors, IgE / Q000097:blood*; D014481:United States
D014408:Biomarkers, Tumor; D017455:Receptors, IgE