Dapsone in rosacea fulminans.
Rosacea fulminans is a rare disease with female predominance characterized by abrupt onset of pustules, papules, and confluent nodules on the face. The conventional treatment consists of systemic glucocorticoids and isotretinoin. We present the case of a 56-year-old woman with a marked facial papulopustular eruption that had followed an initial period of severe seborrhoea. Conventional treatment produced no clear improvement. Dapsone treatment achieved complete healing in 5 weeks.
Bormann
G
G
Department of Dermatology and Venerology, Martin-Luther-University Halle-Wittenberg, (Saale), Germany. gisela.bormann@medizin.uni-halle.de
Gaber
G
G
Fischer
M
M
Marsch
W C
WC
D000284:Administration, Oral; D001707:Biopsy, Needle; D002927:Cimetidine / Q000008:administration & dosage; D003622:Dapsone / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005148:Facial Dermatoses / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D012393:Rosacea / Q000175:diagnosis* / Q000188:drug therapy*; D012720:Severity of Illness Index; D016896:Treatment Outcome
D002927:Cimetidine; D003622:Dapsone