[Macrocytic anemia and neurological signs due to vitamin B-12 deficiency in a breast-fed infant of a strict vegetarian mother].
Vitamin B12 deficiency is a very rare disease of infants and young children in Europe. Authors report a case of a 9.5-month-old infant who was exclusively breast-fed by his vegan mother and developed serious vitamin B12 deficiency in form of neurological regression, repetitive vomiting, drowsiness, dysphagia, obstipation, and tremor. A few days after intramuscular vitamin substitution his abnormal signs improved dramatically, hematological restitution was reached in six weeks. Authors describe the hematological and neurological signs, the diagnostic and differential-diagnostic pitfalls, therapy, prognosis, and prevention of this condition. Beside reviewing the literature they emphasize the importance of early recognition and intervention and the need of an appropriate doctor-parent cooperation in this disease.
Fogarasi
A
A
Neurológiai Osztály, Magyarországi Református Egyház Bethesda Gyermekkórháza, Budapest.
Neuwirth
M
M
Békési
A
A
Bocskai
E
E
D000328:Adult; D000748:Anemia, Macrocytic / Q000209:etiology*; D001942:Breast Feeding; D003937:Diagnosis, Differential; D014676:Diet, Vegetarian / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D008297:Male; D009468:Neuromuscular Diseases / Q000209:etiology*; D011379:Prognosis; D014805:Vitamin B 12 / Q000008:administration & dosage; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control
D014805:Vitamin B 12
Anyai vegan diéta talaján kialakult csecsemókori B12-vitaminhiányos macrocytaer anaemia idegrendszeri tünetekkel.