[Behavioral disorders caused by acute and chronic manganese intoxications of white rats].
Single per oral administration of manganese chloride induced an obvious reversible diminishing of locomotor activity in white rats as well as deterioration of avoidance response to unconditioned and conditioned stimuli, prolongation of the conditioning latency, and a temporary deterioration of learning. Chronic manganese intoxication produced an irreversible learning disability and a slight memory disorders.
Shukakidze
A
A
Tbilisi State Medical University.
Lazriev
I
I
Mitagvariia
N
N
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects*; D002712:Chlorides / Q000008:administration & dosage / Q000633:toxicity*; D007858:Learning / Q000187:drug effects*; D017895:Manganese Compounds / Q000008:administration & dosage; D008568:Memory / Q000187:drug effects; D051381:Rats; D023382:Toxicity Tests, Acute
D002712:Chlorides; D017895:Manganese Compounds; C025340:manganese chloride
Povedencheskie narusheniia pri ostroĭ i khronicheskoĭ margantsevoĭ intoksikatsiiakh belykh krys.