Effects of acidum vitamin A on tyrosinase activity.
OBJECTIVE
To investigate the effect of acidum vitamin A on tyrosinase activity and provide experimental evidence for therapy of pigment disorder of skin.


METHODS
Tyrosinase activity was estimated by measuring the rate of oxidation of DL-dopa.


RESULTS
The levels of tyrosinase activity in the acidum vitamin A group were significantly greater than those of the control group (P < 0.01).


CONCLUSIONS
Tyrosinase activity can be increasingly induced by acidum vitamin A.
Li
H
H
Department of Dermatology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Zhu
W
W
D006801:Humans; D014442:Monophenol Monooxygenase / Q000235:genetics / Q000378:metabolism*; D010858:Pigmentation / Q000187:drug effects; D018168:Receptors, Retinoic Acid / Q000187:drug effects / Q000502:physiology; D014212:Tretinoin / Q000494:pharmacology*
D018168:Receptors, Retinoic Acid; D014212:Tretinoin; D014442:Monophenol Monooxygenase