title: An MKM-mounted instrument holder for frameless point-stereotactic procedures: a phantom-based accuracy evaluation.
abstract: To enable the use of the Mehrkoordinaten Manipulator (MKM) robotic navigation system for frameless point stereotactic procedures, a new instrument holder is presented. A phantom-based accuracy study was performed in which this new method was compared with frame-based procedures performed using the Brown-Roberts-Wells (BRW) stereotactic frame. The authors acquired computerized tomography scans of a test phantom, consisting of 19 acrylic plastic target rods on a circular base. These images were used in frame-based (BRW) and frameless (MKM) localization experiments. In both cases the authors calculated the distances between the actual target positions and the positions reached stereotactically. The mean application accuracy (target registration error) was 0.68 mm when the BRW frame was used and 0.96 mm when the MKM system was used after manual repositioning of the microscope (p < 0.001). Positioning accomplished using robotics only demonstrated a slightly larger inaccuracy: 1.47 mm (p < 0.005). Because the surgeon is concerned with the largest error in an individual case rather than the mean error in a large number of cases, the mean + three standard deviations was also compared. This value differed very little between the manually positioned MKM system and the BRW frame (2.04 mm and 1.84 mm, respectively). Although repeatability per target appeared to be slightly better when the BRW frame was used, accuracy was more homogeneous over the phantom volume when the MKM system was used (both differences were not significant). In conclusion, the accuracy of point stereotactic procedures performed using an instrument holder attached to the system is comparable with the accuracy of procedures involving a stereotactic frame. Moreover, the frameless techniques and robotic features of the MKM enable a more surgeon- and patient-friendly stereotactic procedure.
authors.affiliation: Department of Neurosurgery and Image Sciences Institute, University Medical Center, Utrecht, The Netherlands. p.willems@neuro.azu.nl
authors.forename: P W
authors.initials: PW
authors.lastname: Willems
authors.forename: H J
authors.initials: HJ
authors.lastname: Noordmans
authors.forename: J W
authors.initials: JW
authors.lastname: Berkelbach van der Sprenkel
authors.forename: M A
authors.initials: MA
authors.lastname: Viergever
authors.forename: C A
authors.initials: CA
authors.lastname: Tulleken
mesh_terms: D001706:Biopsy / Q000295:instrumentation; D001921:Brain / Q000473:pathology* / Q000601:surgery*; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006801:Humans; D019635:Neurosurgical Procedures / Q000295:instrumentation*; D015203:Reproducibility of Results; D013238:Stereotaxic Techniques / Q000295:instrumentation* / Q000592:standards