Local drug delivery in the treatment of periodontitis.
The current data suggest that local delivery of antimicrobials into the periodontal pocket can improve periodontal health. However, they do not provide a superior result to scaling and root planing. In conjunction with scaling and root planing, the adjunctive use of local drug delivery devices may enhance the results in sites which do not respond to conventional therapy.
Stanford
T W
TW
Department of Periodontics, TAMUS-Baylor College of Dentistry, USA.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D002710:Chlorhexidine / Q000008:administration & dosage; D004318:Doxycycline / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004342:Drug Hypersensitivity / Q000209:etiology; D004352:Drug Resistance, Microbial; D006801:Humans; D008911:Minocycline / Q000008:administration & dosage; D010514:Periodontal Pocket / Q000378:metabolism; D010518:Periodontitis / Q000188:drug therapy*; D013752:Tetracycline / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D013752:Tetracycline; D008911:Minocycline; D004318:Doxycycline; D002710:Chlorhexidine