title: Highly selective synthesis of heterosubstituted aromatic sulfamides.
abstract: The sulfamide functional group is increasingly relevant in both medicinal and supramolecular chemistry, yet few selective synthetic steps are available for its elaboration. We report here a mild, general, and efficient method for the selective differentiation of N-atom substituents of aromatic sulfamides. [reaction: see text]
authors.affiliation: The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, MB-26, La Jolla, California 92037, USA.
authors.forename: F
authors.initials: F
authors.lastname: Hof
authors.forename: P M
authors.initials: PM
authors.lastname: Iovine
authors.forename: D W
authors.initials: DW
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Rebek
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D013457:Sulfur Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000577:Amides; D013457:Sulfur Compounds