title: [Sodium cromoglycate in the treatment of food hypersensitivity in children under 3 years of age].
abstract: Dietary elimination is a treatment of first choice in food hypersensitivity. Such therapy is not always enough to stop the disease and introduction of pharmacological treatment is necessary. In prevention and long term treatment antiallergic drugs are recommended. The aim of the study was to assess efficacy and safety of oral sodium cromoglycate in treatment of food hypersensitivity in the youngest children. In our study we examined: the group of 25 children aged 6 months-3 years treated with oral cromolyn sodium during the period 4-20 weeks and 29 children aged 6 months-3 years treated with ketotifen. Symptoms from skin, digestive and respiratory tract, behaviour status were evaluated for drugs efficacy. Cromolyn and ketotifen effected a significant decrease in total symptoms score. The treatment was well tolerated. No serious side effects were noted. The incidents of skin rash, disquiet during the night, diarrhoea and urticaria were only 8 percent. Sodium cromoglycate is safe and effective drug in treatment of food allergy in children; specially in symptoms from gastrointestinal tract and multi-organs allergy.
authors.affiliation: III Klinika Chorób Dzieci AM w Białymstoku.
authors.forename: E
authors.initials: E
authors.lastname: Zur
authors.forename: M
authors.initials: M
authors.lastname: Kaczmarski
mesh_terms: D018926:Anti-Allergic Agents / Q000627:therapeutic use*; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D004205:Cromolyn Sodium / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D005512:Food Hypersensitivity / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007665:Ketotifen / Q000627:therapeutic use*; D008297:Male; D011446:Prospective Studies
chemical_list: D018926:Anti-Allergic Agents; D018927:Anti-Asthmatic Agents; D004205:Cromolyn Sodium; D007665:Ketotifen
vernacular_title: Kromoglikan disodowy w leczeniu nadwrazliwości pokarmowej u dzieci do 3. roku zycia.