[Familial brain abscess as a complication of hereditary hemorrhagic telangiectasia].
The hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease) is an inherited autosomal dominant disease with angiodysplasia of the skin, mucosa, parenchymal organs, and it can affect the central nervous system. In 40% of the cases neurological complications, most frequently intracerebral abscesses occur. In this study, the case history of a patient with central nervous system manifestation of hereditary hemorrhagic telangiectasia showing familiar aggregation of brain abscess will be presented. A young male patient was admitted to Neurological Department because of his first epileptic seizure and progressive right hemispheric symptoms. His examinations showed frontal abscess, which was surgically removed. The frequent nose-bleeding of the patient and recurrent brain abscess in his brother's history provided the possibility of hereditary hemorrhagic telangiectasia. The background of brain abscess were multiple pulmonary arteriovenous malformation, which were embolized by repeated angiography. Familiar brain abscess is very rare. However, in the case of brain abscess especially with familiarity diagnosis of the Rendu-Osler-Weber disease should be considered.
Szöts
M
M
Pécsi Tudományegyetem, Altalános Orvostudományi Kar, Neurológiai Klinika. szots@neuro.pote.hu
Szapáry
L
L
Nagy
F
F
Vetö
F
F
D000328:Adult; D001922:Brain Abscess / Q000209:etiology* / Q000235:genetics; D006801:Humans; D008297:Male; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications*
Hereditaer haemorrhagiás teleangiectasia szövódményeként kialakult agytályog családi halmozódása.