Reactive metabolite screen for reducing candidate attrition in drug discovery.
Chen
W G
WG
Drug Metabolism Development, Pfizer Central Research, Groton, CT 06340, USA.
Zhang
C
C
Avery
M J
MJ
Fouda
H G
HG
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D008862:Microsomes, Liver / Q000378:metabolism*