Therapeutic potential of bone morphogenetic proteins.
Recently, there has been substantial progress in the area of bone morphogenetic protein (BMP) research. This review serves as an up-to-date summary of the history of BMPs, the mechanisms of BMP signalling and the role of BMPs in adipose, kidney, liver, bone and nervous system. The potential of BMPs as therapeutic agents will also be discussed.
Azari
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K
Bone Tissue Engineering Center, Carnegie Mellon University, 125 Smith Hall, 5000 Forbes Avenue, Pittsburgh, PA 15213, USA. kodiazari@yahoo.com
Doll
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Sfeir
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Hollinger
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D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000145:classification / Q000378:metabolism / Q000627:therapeutic use*; D006801:Humans
D019485:Bone Morphogenetic Proteins