title: Bilateral papilloedema associated with lumbo-sacral intraspinal tumor.
abstract: OBJECTIVE
  To study the possible mechanism of bilateral papilloedema associated with intraspinal tumor at the lumbo-sacral level.
  
  
  METHODS
  Three cases were reported. Detailed clinical history was evaluated. Patients were followed up for 2, 3 and 5 months after resection of the tumor. Related literature was reviewed.
  
  
  RESULTS
  Papilloedema was soon resolved and the level of protein in the cerebrospinal fluid (CSF) decreased significantly after resection of tumor. These indicated a close relationship between papilloedema, CSF protein and intraspinal tumor.
  
  
  CONCLUSIONS
  This is the first report of papilloedema associated with a lumbo-sacral intraspinal tumor in Chinese literature. The high level of protein in CSF may be the cause of both papilloedema and increased intracranial pressure. In patients with bilateral papilloedema, if no intracranial cause could be found, lumbo-sacral intraspinal tumor should be considered.
authors.affiliation: Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: Y
authors.initials: Y
authors.lastname: Lao
authors.forename: Y
authors.initials: Y
authors.lastname: Guo
authors.forename: H
authors.initials: H
authors.lastname: Guo
mesh_terms: D000328:Adult; D002555:Cerebrospinal Fluid / Q000737:chemistry; D005260:Female; D006801:Humans; D007427:Intracranial Pressure; D008161:Lumbosacral Region; D008297:Male; D010211:Papilledema / Q000209:etiology*; D011506:Proteins / Q000032:analysis; D013120:Spinal Cord Neoplasms / Q000134:cerebrospinal fluid / Q000150:complications* / Q000503:physiopathology
chemical_list: D011506:Proteins