Synthesis of paucidisperse poly(gamma-benzyl-alpha,L-glutamate) oligomers and star polymers with rigid arms.
The synthesis of highly uniform gamma-benzyl-alpha,L-glutamate (BLG) oligomers via a convergent solution phase approach is reported. BLG oligomers were produced with designed lengths of 4, 8, 12, and 16 as a first step to production of BLG-4-mer and BLG-8-mer rod stars. The star oligomers were purified by size-exclusion chromatography and reversed phase HPLC, and characterized by MALDI-TOF mass spectrometry and reversed phase HPLC. These star-shaped BLG oligomers could be used as initiators for growing larger stars.
Wang
X
X
Department of Chemistry and Macromolecular Studies Group, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Daly
W H
WH
Russo
P
P
Ngu-Schwemlein
M
M
D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D009842:Oligopeptides / Q000138:chemical synthesis / Q000302:isolation & purification / Q000592:standards; D011099:Polyglutamic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000302:isolation & purification / Q000592:standards; D017433:Protein Structure, Secondary; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D009842:Oligopeptides; C003172:poly-gamma-benzyl-L-glutamate; D011099:Polyglutamic Acid