[Observation of preventing and treating effect of Salvia miltiorrhiza composita on patients with ischemic coronary heart disease undergoing non-heart surgery].
OBJECTIVE
To observe the preventing and treating effect of Salvia miltiorrhiza composita (SMC) on patients with ischemic coronary heart disease (CHD) undergoing non-heart surgery.


METHODS
The 108 patients were randomly divided into the control group and treatment group. In the treatment group, each patient of 54 were administered SMC intravenously during the operation. ECG, HR, MAP and SpO2 were observed and bleeding quantity was measured perioperatively.


RESULTS
Effective rate of ECG in treatment group was 90.7% (49/54 cases) and the control group was 35.2% (19/54 cases). There was significant difference between the two groups (P < 0.01). HR of the treatment group was no great flutter but control group became faster (P < 0.05). MAP and SpO2 of the two groups were no significant difference perioperatively. There was no significant difference to bleeding quantity between the two groups.


CONCLUSIONS
SMC could effectively improve and protect myocardial ischemia in patients with CHD undergoing non-heart surgery, and no side effect was found.
Zhou
S
S
Shandong University of TCM, Jinan (250014).
Shao
W
W
Duan
C
C
D000368:Aged; D003327:Coronary Disease / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005121:Extremities / Q000601:surgery; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts; D027561:Salvia miltiorrhiza; D014665:Vasodilator Agents / Q000627:therapeutic use*
D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; D014665:Vasodilator Agents