title: A case of laryngeal aspergillosis following radiation therapy.
abstract: Primary laryngeal aspergillosis is extremely rare. It is commonly seen as a part of a systemic infection involving the respiratory system in an immunocompromised host. Differential diagnosis is important, as the clinical symptoms are similar to those of malignant laryngeal disease. We describe a 73-year-old man with a history of hoarseness. He had a history of radiotherapy for laryngeal squamous cell carcinoma and had a history of diabetes. Direct laryngoscope and biopsy confirmed the diagnosis of aspergillus. We cauterized the lesion with a CO(2) laser. In the present case, irradiation seemed to have played a more important role in the onset of this disease rather than diabetes.
authors.affiliation: Department of Otorhinolaryngology, Hachiouji Medical Center of Tokyo Medical University, 1163 Tate Hachiouji-shi, Tokyo 193-0944, Japan. yogawa21@hotmail.com
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Nishiyama
authors.forename: Akira
authors.initials: A
authors.lastname: Hagiwara
authors.forename: Takahisa
authors.initials: T
authors.lastname: Ami
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fujita
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yoshida
authors.forename: Mamoru
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis / Q000382:microbiology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D007830:Larynx / Q000382:microbiology* / Q000528:radiation effects*; D053685:Laser Therapy; D008297:Male; D011183:Postoperative Complications; D011878:Radiotherapy / Q000009:adverse effects*