title: Optimized shielding for space radiation protection.
abstract: Future deep space mission and International Space Station exposures will be dominated by the high-charge and -energy (HZE) ions of the Galactic Cosmic Rays (GCR). A few mammalian systems have been extensively tested over a broad range of ion types and energies. For example, C3H10T1/2 cells, V79 cells, and Harderian gland tumors have been described by various track-structure dependent response models. The attenuation of GCR induced biological effects depends strongly on the biological endpoint, response model used, and material composition. Optimization of space shielding is then driven by the nature of the response model and the transmission characteristics of the given material.
authors.affiliation: NASA Langley Research Center, Hampton, VA 23681, USA. john.w.wilson@larc.nasa.gov
authors.forename: J W
authors.initials: JW
authors.lastname: Wilson
authors.forename: F A
authors.initials: FA
authors.lastname: Cucinotta
authors.forename: M H
authors.initials: MH
authors.lastname: Kim
authors.forename: W
authors.initials: W
authors.lastname: Schimmerling
mesh_terms: D000535:Aluminum; D000818:Animals; D002461:Cell Line, Transformed; D003359:Cosmic Radiation; D004307:Dose-Response Relationship, Radiation; D006243:Harderian Gland / Q000528:radiation effects; D006801:Humans; D006859:Hydrogen; D018499:Linear Energy Transfer; D011835:Radiation Protection / Q000295:instrumentation*; D012062:Relative Biological Effectiveness; D012306:Risk; D012867:Skin / Q000528:radiation effects; D013026:Space Flight / Q000295:instrumentation*
chemical_list: D006859:Hydrogen; D000535:Aluminum