title: Spontaneous haemoperitoneum from surreptitious ingestion of a rodenticide.
abstract: Superwarfarins have progressively replaced warfarin as rodenticides as they are more potent and have a longer anticoagulant activity. Human exposure may be complicated by spontaneous haemorrhage in various sites. We report the case of a 51-year-old woman who was admitted with spontaneous haemoperitoneum and intramural haematoma along the small intestine. After the evidence of a deficit of vitamin K1-dependent clotting factors (II, VII, IX, X), the patient admitted that she was chronically ingesting difenacoum. She was successfully treated with fresh frozen plasma and vitamin K1. Follow-up was not accepted.
authors.affiliation: Department of Intensive Care, Cliniques Universitaires St-Luc, Brussels, Belgium.
authors.forename: L
authors.initials: L
authors.lastname: Soubiron
authors.forename: P
authors.initials: P
authors.lastname: Hantson
authors.forename: I
authors.initials: I
authors.lastname: Michaux
authors.forename: M
authors.initials: M
authors.lastname: Lambert
authors.forename: P
authors.initials: P
authors.lastname: Mahieu
authors.forename: J
authors.initials: J
authors.lastname: Pringot
mesh_terms: D015110:4-Hydroxycoumarins / Q000506:poisoning*; D000925:Anticoagulants / Q000506:poisoning*; D017809:Fatal Outcome; D005260:Female; D006465:Hemoperitoneum / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D012378:Rodenticides / Q000506:poisoning*
chemical_list: D015110:4-Hydroxycoumarins; D000925:Anticoagulants; D012378:Rodenticides; C012903:difenacoum