The relationship between pressure ulcers and skin blood flow response after a local cold provocation.
OBJECTIVE
To study the relationship between an impaired blood flow response after a local cold stimulus, testing nerve regulation of the local blood flow response, and an increased risk of developing pressure ulcers.


METHODS
An observational, longitudinal, prospective study.


METHODS
Dutch nursing home.


METHODS
Eighty-two newly admitted somatic nursing home patients, age 60 years and older.


METHODS
A local cold stimulus (17 degrees C) applied to the trochanter major.


METHODS
On admission, blood flow response to a local cold stimulus. As the stimulus was withdrawn, the temperature measured at the skin increased asymptotically toward the final temperature, T(f). The velocity of this rise was characterized by the time constant, tau, of the process. On admission, and weekly during a 4-week follow-up period, the presence or absence of pressure ulcers was verified.


RESULTS
The blood flow response time correlated significantly with the risk of developing pressure ulcers. The patients who developed pressure ulcers during the follow-up period had a significantly longer response time than the patients who did not.


CONCLUSIONS
Malfunction of the nervous regulatory mechanisms of the local blood flow is partially responsible for an increased susceptibility to pressure ulcer formation.
van Marum
Rob J
RJ
Department of General Practice, Nursing Home Medicine and Social Medicine/Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands. rvmarum@knmg.nl
Meijer
Jan H
JH
Ribbe
Miel W
MW
D003080:Cold Temperature; D005260:Female; D006801:Humans; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D003668:Pressure Ulcer / Q000503:physiopathology*; D011446:Prospective Studies; D012039:Regional Blood Flow / Q000502:physiology; D012867:Skin / Q000098:blood supply*; D012881:Skin Temperature; D014661:Vasoconstriction