Micellar electrokinetic chromatography--from theoretical concepts to real samples (review).
Micellar electrokinetic chromatography (MEKC) is an alternative to liquid chromatographic separations. It is a highly efficient separation technique that is performed with the same experimental set-up as is used for capillary electrophoresis (CE), thus extending the applicability of CE to neutral solutes. MEKC can be regarded as a separation technique with a similar scope to that of reversed-phase high-performance liquid chromatography (RP-HPLC), having advantages over HPLC with regard to the efficiency of the separation system, separation speed, cost, and tolerance to matrix constituents. This paper discusses the applicability of MEKC to real samples and also addresses developments widening the scope of this emerging technique: on-line concentration by stacking or sweeping and sensitive detection schemes.
Pyell
U
U
University GH Kassel, Department of Biology/Chemistry, Germany. pyellute@uni-kassel.de
D000818:Animals; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000295:instrumentation; D004785:Environmental Pollutants / Q000032:analysis; D005504:Food Analysis; D005554:Forensic Medicine; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis
D004785:Environmental Pollutants; D004364:Pharmaceutical Preparations