Membrane-associated MMP regulators: novel cell adhesion tumor suppressor proteins?
Matrix metalloproteinases are enzymes that regulate tissue behavior by interactions with extracellular matrix proteins. RECK, a membrane-anchored inhibitor of MMPs was recently characterized for its role in development, tissue homeostasis, and for tumor angiogenesis.
Weaver
Valerie M
VM
Department of Pathology and Laboratory Medicine, University of Pennsylvania, 3340 Smith Walk, Philadelphia, PA 19104, USA.
D002448:Cell Adhesion / Q000502:physiology; D005057:Eukaryotic Cells / Q000166:cytology / Q000201:enzymology; D020782:Matrix Metalloproteinases / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000378:metabolism*
D025521:Tumor Suppressor Proteins; D020782:Matrix Metalloproteinases