[Quantitative evaluation of Streptococcus mutans and Candida species and salivary factors in the oral cavity of patient undergoing radiotherapy].
The aim of this study was to quantify the microorganisms Streptococcus mutans and Candida sp in the oral cavity of patients with oropharynx carcinoma, before, during and after radiotherapy, and to correlate the results with salivary factors such as pH, buffer capacity (CT) and flow rate (FS). Saliva samples were collected, diluted and inoculated in SB-20 agar and in Sabouraud agar, for Streptococcus mutans and Candida sp, respectively. Previously to dilution, the concentrated saliva was analyzed, and the salivary factors were determined. After the growth of colonies, the number of microorganisms was determined in CFU/ml. The analysis of the results allowed to conclude that the salivary factors are related to the presence of microorganisms, and that the number of CFU/ml increased as salivary flow rate decreased. The effects of radiation compromised salivary homeostasis and favored the increase of infection by yeasts and bacteria.
Spolidorio
D M
DM
Disciplina de Patologia, Faculdade de Odontologia de Araraquara, UNESP.
Spolidorio
L C
LC
Barbeiro
R H
RH
Höfling
J F
JF
Bernardo
W L
WL
Pavan
S
S
D000704:Analysis of Variance; D002175:Candida / Q000302:isolation & purification*; D002294:Carcinoma, Squamous Cell / Q000382:microbiology* / Q000532:radiotherapy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009959:Oropharyngeal Neoplasms / Q000382:microbiology* / Q000532:radiotherapy; D012463:Saliva / Q000737:chemistry / Q000378:metabolism / Q000382:microbiology*; D013295:Streptococcus mutans / Q000302:isolation & purification*
Avaliação quantitativa de Streptococcus do grupo mutans e Candida sp e fatores salivares na cavidade bucal de pacientes submetidos à radioterapia.