[Clinical and experimental study on treatment of Helicobacter pylori infected gastritis by xialian yiyou capsule].
OBJECTIVE
To observe the therapeutic effect of Xialian Yiyou Capsule (XLYYC) on helicobacter pylori (HP) infected gastritis to develop the serial Chinese classical recipe.


METHODS
HP infected patients were divided into two groups, 136 patients in the XLYYC group treated with XLYYC and 90 patients in the control group treated with Lizhu Dele Capsule, for 4 weeks as one therapeutic course, the clinical therapeutic effect was observed, and corresponding animal experiments were done.


RESULTS
Clinical effect of the XLYYC group was better than that of the control group in improving clinical symptoms, relieving inflammation of gastric mucosa and eliminating HP (P < 0.05, P < 0.01). Results of animal experiment showed that XLYYC was superior than the control significantly in anti-inflammation, analgesia, stomach emptying and curing gastric ulcer model (P < 0.05, P < 0.01). Without any adverse reaction has been found in acute toxicologic study.


CONCLUSIONS
The therapeutic effect of XLYYC in treating HP infected gastritis was definite and safe, non-toxic.
Ji
A
A
First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000).
Zhao
W
W
Wang
Z
Z
D000293:Adolescent; D000328:Adult; D000368:Aged; D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005756:Gastritis / Q000188:drug therapy* / Q000382:microbiology; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy
D002214:Capsules; D004365:Drugs, Chinese Herbal