Design and characterization of a novel "family-shuffling" technology adapted to membrane enzyme: application to P450s involved in xenobiotic metabolism.
Abécassis
V
V
Centre de Génétique Moléculaire, CNRS, Gif-sur-Yvette, France.
Pompon
D
D
Truan
G
G
D002462:Cell Membrane / Q000201:enzymology; D019363:Cytochrome P-450 CYP1A1 / Q000235:genetics / Q000378:metabolism*; D019388:Cytochrome P-450 CYP1A2 / Q000235:genetics / Q000378:metabolism*; D015870:Gene Expression; D015723:Gene Library; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D012441:Saccharomyces cerevisiae; D015262:Xenobiotics
D015262:Xenobiotics; D019363:Cytochrome P-450 CYP1A1; D019388:Cytochrome P-450 CYP1A2