title: Role of LIM domains in mediating signaling protein interactions.
abstract: LIM domains are double zinc-finger motifs that mediate protein interactions between transcription factors, cytoskeletal and signaling proteins. This review outlines the protein interactions mediated by LIM domains with signaling proteins including tyrosine and serine/threonine kinases and phosphatases.
authors.affiliation: Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Australia. Susan.brown@med.monash.edu.au
authors.forename: S
authors.initials: S
authors.lastname: Brown
authors.forename: I D
authors.initials: ID
authors.lastname: Coghill
authors.forename: M J
authors.initials: MJ
authors.lastname: McGrath
authors.forename: P A
authors.initials: PA
authors.lastname: Robinson
mesh_terms: D000199:Actins / Q000378:metabolism; D016384:Consensus Sequence; D003598:Cytoskeletal Proteins / Q000737:chemistry* / Q000378:metabolism*; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D011493:Protein Kinase C / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D017434:Protein Structure, Tertiary; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D014157:Transcription Factors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D016335:Zinc Fingers
chemical_list: D000199:Actins; D003598:Cytoskeletal Proteins; D014157:Transcription Factors; D011505:Protein-Tyrosine Kinases; D017346:Protein Serine-Threonine Kinases; D011493:Protein Kinase C; D010744:Phosphoric Monoester Hydrolases