title: Intracoronary stent implantation under intracoronary ultrasound guidance with aspirin and ticlopidine therapy.
abstract: OBJECTIVE
  To observe the immediate angiographic and intravascular ultrasound (IVUS) results and their effects on one month clinical outcomes in forty-one patients who submitted to coronary stent deployment with IVUS guidance.
  
  
  METHODS
  All patients were allocated to coronary stent implantation with high inflation pressure. After good angiographic results (< 20% residual stenosis), all patients underwent IVUS and higher-pressure dilatation would be necessary if criteria for optimal coronary stent implantation were not met. The optimal criterion of IVUS for stent implantation was the ratio of intrastent lumen cross-sectional area to the average of the proximal and distal reference lumen cross-sectional areas > or = 80%. All patients had aspirin and ticlopidine therapy on the day of angioplasty and during the one month follow-up period.
  
  
  RESULTS
  Optimal criteria of IVUS were obtained without any further intrastent dilatation in twenty-five patients but intrastent higher-pressure dilatation was performed in fourteen patients whose ultrasound results did not reach the criteria. In these patients, we increased the minimal intrastent lumen area 25.7% (P < 0.05). Thirty-five patients (90%) had good minimal intrastent lumen area of IVUS. There were no deaths, myocardial infarction, acute stent thrombosis or need for revascularization during the study and the one month follow-up.
  
  
  CONCLUSIONS
  Intracoronary stent deployment under IVUS guidance, including combining aspirin and ticlopidine therapy, had beneficial ultrasound results and good clinical outcomes after one month follow-up.
authors.affiliation: Department of Cardiology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China.
authors.forename: D
authors.initials: D
authors.lastname: Zhang
authors.forename: X
authors.initials: X
authors.lastname: Cai
authors.forename: W
authors.initials: W
authors.lastname: Shen
authors.forename: F
authors.initials: F
authors.lastname: Schiele
authors.forename: J P
authors.initials: JP
authors.lastname: Bassand
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001241:Aspirin / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000628:therapy; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents; D013988:Ticlopidine / Q000627:therapeutic use*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods*
chemical_list: D005343:Fibrinolytic Agents; D013988:Ticlopidine; D001241:Aspirin