title: Benefit of pacing and beta-blockers in idiopathic repetitive polymorphic ventricular tachycardia.
abstract: An 18-year-old woman presented with recurrent exercise-induced syncopal episodes and severe systolic dysfunction. ECG monitoring disclosed repetitive polymorphic ventricular complexes, paroxysms of bidirectional ventricular tachycardia, and nonsustained bursts of slow polymorphic ventricular tachycardia that increased in length and rate during exercise. Ventricular arrhythmias were refractory to medical treatment, which included verapamil and beta-blockers. Addition of permanent atrial pacing to beta-blocker therapy suppressed the arrhythmias and reversed systolic impairment in the following months.
authors.affiliation: Laboratory of Electrophysiology, Division of Cardiology, Insular University Hospital, Las Palmas, Spain. npc@jet.es
authors.forename: N
authors.initials: N
authors.lastname: Pérez-Castellano
authors.forename: J C
authors.initials: JC
authors.lastname: Rodríguez
authors.forename: O
authors.initials: O
authors.lastname: Medina
authors.forename: V
authors.initials: V
authors.lastname: Nieto
mesh_terms: D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D002304:Cardiac Pacing, Artificial; D003937:Diagnosis, Differential; D004562:Electrocardiography; D015444:Exercise; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011110:Polymorphism, Genetic; D012008:Recurrence; D013575:Syncope / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D017180:Tachycardia, Ventricular / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists