title: Clinical evaluation of an adhesive used as a fissure sealant.
abstract: OBJECTIVE
  To compare the retention of a multi-use bonding agent (OptiBond) to a conventional sealant (Delton) used as pit and fissure sealants.
  
  
  METHODS
  An informed consent was obtained from 38 subjects aged 11-17 yrs. Delton, a self-cured sealant, was applied to 86 teeth, and OptiBond, a dual-cure glass filled adhesive, was applied to 85 teeth, under cotton roll isolation and saliva ejector. Each subject received both sealing materials, randomly assigned to the sides of the mouth. The sealed teeth were followed up to 30 months. Clinical evaluation was performed by two examiners and the retention was classified as failure or success.
  
  
  RESULTS
  Statistical analysis based on a stratified Cox proportional hazards regression model indicated that OptiBond had better clinical performance than Delton (P < 0.001).
authors.affiliation: Department of Dental Materials, School of Dentistry, University of São Paulo, Brazil. rhmgrand@fo.usp.br
authors.forename: R H
authors.initials: RH
authors.lastname: Grande
authors.forename: A C
authors.initials: AC
authors.lastname: de Lima
authors.forename: L E
authors.initials: LE
authors.lastname: Rodrigues Filho
authors.forename: M F
authors.initials: MF
authors.lastname: Witzel
mesh_terms: D000269:Adhesives / Q000737:chemistry / Q000627:therapeutic use; D000293:Adolescent; D001641:Bicuspid; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry / Q000627:therapeutic use; D002648:Child; D016001:Confidence Intervals; D001840:Dental Bonding; D003733:Dental Caries Susceptibility; D017220:Dentin-Bonding Agents / Q000737:chemistry / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008963:Molar; D015588:Observer Variation; D010895:Pit and Fissure Sealants / Q000627:therapeutic use*; D016016:Proportional Hazards Models; D019279:Resin Cements / Q000737:chemistry / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000269:Adhesives; D017220:Dentin-Bonding Agents; C092987:Optibond; D010895:Pit and Fissure Sealants; D019279:Resin Cements; D017438:Bisphenol A-Glycidyl Methacrylate