title: Thrombocytopenia and emperipolesis in a patient with hepatitis a infection.
abstract: lmmune thrombocytopenia is a benign, self-limiting disease in children, responding well to treatment and generally associated with viral infections. A 13-year-old girl was admitted to a hospital with the epistaxis and purpura after an attack of jaundice 6 weeks before. The diagnosis of hepatitis A virus (HAV)-induced thrombocytopenia was made. Furthermore, erythrophagocytosis by megakaryocytes was demonstrated in the bone marrow of the patient. Although hematologic complications following hepatitis B and C viruses are commonly reported, the association of hepatitis A virus and thrombocytopenia has rarely been described.
authors.affiliation: Hacettepe University School of Medicine, Department of Pediatrics, Ankara, Turkey. zavcias@yahoo.com
authors.forename: Zekai
authors.initials: Z
authors.lastname: Avci
authors.forename: Tuba
authors.initials: T
authors.lastname: Turul
authors.forename: Ferhat
authors.initials: F
authors.lastname: Catal
authors.forename: Seref
authors.initials: S
authors.lastname: Olgar
authors.forename: Ali
authors.initials: A
authors.lastname: Baykan
authors.forename: Ozlem
authors.initials: O
authors.lastname: Tekfam
authors.forename: A
authors.initials: A
authors.lastname: Gürgey
mesh_terms: D000293:Adolescent; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006506:Hepatitis A / Q000150:complications*; D006801:Humans; D008533:Megakaryocytes / Q000473:pathology*; D009196:Myeloproliferative Disorders / Q000209:etiology* / Q000473:pathology; D010587:Phagocytosis; D013921:Thrombocytopenia / Q000209:etiology*