Adenoviruses encoding HPRT correct the biochemical abnormalities fully only in HPRT-deficient human cell lines: importance of species differences.
Southgate
T
T
Molecular Medicine and Gene Therapy Unit, School of Medicine, University of Manchester, GB.
Bain
D
D
Fairbanks
L D
LD
Morelli
A
A
Larregina
A
A
Simmonds
H A
HA
Castro
M
M
Lowenstein
P
P
D000225:Adenine / Q000378:metabolism; D000260:Adenoviruses, Human; D000818:Animals; D002460:Cell Line; D002470:Cell Survival; D018014:Gene Transfer Techniques; D005822:Genetic Vectors; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D019271:Hypoxanthine / Q000378:metabolism; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics*; D051379:Mice; D014527:Uric Acid / Q000378:metabolism; D014532:Uridine Diphosphate Glucose / Q000378:metabolism; D019820:Xanthine / Q000378:metabolism
D019820:Xanthine; D014527:Uric Acid; D019271:Hypoxanthine; D006160:Guanosine Triphosphate; D007041:Hypoxanthine Phosphoribosyltransferase; D000225:Adenine; D014532:Uridine Diphosphate Glucose