title: Tuberculosis in kudus (Tragelaphus strepsiceros) in the Kruger National Park.
abstract: Five kudus (Tragelaphus strepsiceros), three bulls and two cows, within the Greater Kruger National Park complex, were diagnosed with generalized tuberculosis caused by Mycobacterium bovis. The lesions seen in these animals were similar to those previously reported in kudus and included severe tuberculous lymphadenitis of the nodes of the head and neck (that resulted in noticeable uni- or bilateral swelling beneath the ear), thorax, and the mesentery. All the animals also suffered from severe granulomatous pneumonia. The lesions in the lungs were more severe cranially and had a miliary distribution elsewhere in the lungs. Based on the DNA patterns of the M. bovis isolates, at least some of these kudus were infected with strains commonly present in tuberculous buffaloes, lions, cheetahs, and baboons in the Park whereas other strains from these kudus were quite different and may reflect another source of infection. The presence of tuberculous kudus in the Park is expected to complicate control measures that may be instituted to contain or eradicate the disease in the Park.
authors.affiliation: State Veterinarian, Skukuza, South Africa.
authors.forename: D F
authors.initials: DF
authors.lastname: Keet
authors.forename: N P
authors.initials: NP
authors.lastname: Kriek
authors.forename: R G
authors.initials: RG
authors.lastname: Bengis
authors.forename: A L
authors.initials: AL
authors.lastname: Michel
mesh_terms: D000818:Animals; D000835:Animals, Wild; D000866:Antelopes; D004269:DNA, Bacterial / Q000032:analysis*; D005260:Female; D005838:Genotype; D008297:Male; D009163:Mycobacterium bovis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012150:Polymorphism, Restriction Fragment Length; D013019:South Africa; D014376:Tuberculosis / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D014388:Tuberculosis, Lymph Node / Q000473:pathology / Q000662:veterinary*
chemical_list: D004269:DNA, Bacterial