Organophosphorus compounds and esterases: current research topics concerning the toxicity of and protection against organophosphates.
This brief review describes the reactions of organophosphorus compounds with cholinesterases, neuropathy target esterase, and phosphoric triester hydrolases with respect to their toxicity. It also describes antidotes, protectors, and decontaminating agents against organophosphates.
Reiner
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Institute for Medical Research and Occupational Health, Zagreb, Croatia. ereiner@imi.hr
D000818:Animals; D000931:Antidotes / Q000737:chemistry; D002265:Carboxylic Ester Hydrolases / Q000737:chemistry; D002802:Cholinesterases / Q000737:chemistry; D004950:Esterases / Q000737:chemistry*; D006801:Humans; D009943:Organophosphorus Compounds / Q000737:chemistry* / Q000633:toxicity; D010091:Oximes / Q000737:chemistry
D000931:Antidotes; D009943:Organophosphorus Compounds; D010091:Oximes; D004950:Esterases; C022635:serine esterase; D002265:Carboxylic Ester Hydrolases; C021859:neurotoxic esterase; D002802:Cholinesterases