title: High variability of HTLV-I in a remote population of Gabon as compared to that of a similar population of French Guiana.
abstract: An anomalous high frequency of ATL was observed in a remote 'noir maroons' village of French Guiana. Since it is not clear if HTLV-I is responsible for different frequencies of disease in different geographical areas, we undertook a comparison of the population with a similar one located in Gabon. We found a much higher degree of gp46 surface envelope glycoprotein sequence conservation in the Guianese village than in the Gabonese one.
authors.affiliation: Immunologie Moléculaire et Parasitologie, Université Bordeaux2, France. daniel.moynet@immol.u-bordeaux2.fr
authors.forename: D
authors.initials: D
authors.lastname: Moynet
authors.forename: J F
authors.initials: JF
authors.lastname: Pouliquen
authors.forename: D
authors.initials: D
authors.lastname: Londos-Gagliardi
authors.forename: R P
authors.initials: RP
authors.lastname: Buigues
authors.forename: J F
authors.initials: JF
authors.lastname: Moreau
authors.forename: I
authors.initials: I
authors.lastname: Bedjabaga
authors.forename: M C
authors.initials: MC
authors.lastname: Georges
authors.forename: A
authors.initials: A
authors.lastname: Talarmin
authors.forename: M
authors.initials: M
authors.lastname: Joubert
authors.forename: H
authors.initials: H
authors.lastname: Fleury
authors.forename: P
authors.initials: P
authors.lastname: Vincendeau
authors.forename: B
authors.initials: B
authors.lastname: Guillemain
mesh_terms: D001483:Base Sequence; D017124:Conserved Sequence; D004279:DNA, Viral; D005260:Female; D005616:French Guiana / Q000453:epidemiology; D005681:Gabon / Q000453:epidemiology; D015686:Gene Products, env / Q000235:genetics; D014644:Genetic Variation; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000453:epidemiology / Q000821:virology*; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D015682:Retroviridae Proteins, Oncogenic / Q000235:genetics; D016415:Sequence Alignment
chemical_list: D004279:DNA, Viral; D015686:Gene Products, env; D015682:Retroviridae Proteins, Oncogenic; C055266:gp46 protein, Human T-cell leukemia virus type I