[Immune and interferon system in patients with bronchial asthma].
We studied the levels of acute inflammation phase proteins (AIPP), production of alpha, gamma and serum interferons, the activity of epsilon-receptors of T-lymphocytes in 39 patients with bronchial asthma (BA). Correlations were made with the process severity and basic therapy. We discovered imbalance of immunoregulatory mechanisms: enhanced AIPP synthesis, low production of induced alpha and gamma interferons, elevated concentrations of poor-differentiated T-lymphocytes. This confirms persisting inflammation in BA.
Artem'eva
O V
OV
Kognovitskaia
A I
AI
Iurina
T M
TM
Semenkov
V F
VF
Serova
L D
LD
Chereĭskaia
N K
NK
Slivets
O N
ON
D001249:Asthma / Q000276:immunology* / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology*; D007372:Interferons / Q000097:blood*; D013601:T-Lymphocytes / Q000276:immunology*
D001426:Bacterial Proteins; D007136:Immunoglobulins; D007372:Interferons
Sostoianie immunnoĭ i interferonovoĭ sistem u bol'nykh bronkhial'noĭ astmoĭ.