A new predictor of improvement in regional left ventricular function assessed by ST/HR slope derived from ST elevation on exercise testing in patients with healed myocardial infarction.
This study evaluates the clinical usefulness of ST/HR slope derived from ST elevation on exercise to predict the improvement in regional wall motion following coronary revascularization in patients with healed myocardial infarction. We studied 58 patients with a diseased, infarct-related and single-vessel coronary artery. The decline calculated from the final 12 data points relating ST-segment elevation to heart rate during exercise were derived (ST/HR slope). Hypokinesis in the infarcted region was assessed by the centerline method and expressed in terms of standard deviations (SD/chord). The increase more than 30% of the SD/chord, which was defined as the improvement in regional wall motion, was seen in 23 of the 30 patients with a ST/HR slope of > or = 5.0 (microV/bpm), and in 4 of the 28 patients with a ST/HR slope <5.0 (microV/bpm) (P <.0001). Thus, a ST/HR slope derived from ST elevation on exercise identifies subgroups of patients who show a good recovery of regional wall motion.
Nakano
Fumio
F
First Department of Internal Medicine, Kagoshima University, Sakuagaoka, Kagoshima, Japan.
Hamasaki
Shuichi
S
Tahara
Minoru
M
Kihara
Koichi
K
Kamekou
Masahiro
M
Tsurugida
Masanori
M
Yoshitama
Takashi
T
Ishida
Sanemasa
S
Yoshikawa
Akiko
A
Kataoka
Tetsurou
T
Saihara
Keishi
K
Minagoe
Shinichi
S
Tei
Chuwa
C
D000328:Adult; D000368:Aged; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013793:Thallium; D016277:Ventricular Function, Left / Q000502:physiology*
D013793:Thallium