Three polymorphisms in the 3' UTR of the TRAIL (TNF-related apoptosis-inducing ligand) gene.
Screening of the TRAIL (TNF-related apoptosis inducing ligand/Apo-2L) gene revealed three single nucleotide polymorphisms (SNPs) in the 3' UTR at nucleotides 1525G/A, 1588G/A, and 1591C/T. Over 50 individuals from each of two populations, Caucasian and African Americans, were genotyped for these three polymorphisms and allele frequencies were determined.
Gray
H L
HL
Department of Human Genetics, The University of Chicago, Chicago, IL 60637, USA.
Sorensen
E L
EL
Hunt
J S
JS
Ober
C
C
D020413:3' Untranslated Regions / Q000235:genetics; D000483:Alleles; D051017:Apoptosis Regulatory Proteins; D005787:Gene Frequency; D006801:Humans; D008562:Membrane Glycoproteins / Q000235:genetics*; D008969:Molecular Sequence Data; D020641:Polymorphism, Single Nucleotide; D053221:TNF-Related Apoptosis-Inducing Ligand; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics*
D020413:3' Untranslated Regions; D051017:Apoptosis Regulatory Proteins; D008562:Membrane Glycoproteins; D053221:TNF-Related Apoptosis-Inducing Ligand; C505653:TNFSF10 protein, human; D014409:Tumor Necrosis Factor-alpha