Dominant right ventricular infarction: is angioplasty the optimal therapeutic approach?
Approximately 30% of all acute inferior myocardial infarctions (AIMI) are accompanied by acute right ventricular infarction (ARVI) as a consequence of proximal right coronary artery (RCA) occlusion. Fifty per cent of all patients with ARVI manifest hypotension, jugular venous distension, and dyspnoea with clear lung fields, which is then considered as dominant acute RVI (ARVI). The in hospital mortality rate of patients with ARVI who are treated traditionally is very high. Thrombolytic therapy is relatively ineffective, while primary angioplasty is a more recent approach yet to be established as optimal treatment for patients with ARVI. Thirty-eight patients with dominant ARVI were admitted to our CCU over a period of 24 months. The patients were retrospectively divided into 3 groups according to treatment: Group I (n = 16): traditional treatment; Group II (n = 12): thrombolytic therapy (streptokinase); Group III (n = 10): angioplasty after urgent coronarography. We tested the difference in the number of deaths in all groups by the Fisher exact test. There was a significant difference in the number of deaths between Group I and Group III (P < 0.05). Mortality reduction was also noted between Group II and Group III, which, however, proved to be statistically insignificant.
Pintarić
H
H
Division of Cardiology, Department of Internal Medicine, University Hospital Sestre Milosrdnice, Vinogradska 29, CR-10000 Zagreb, Croatia.
Nikolić-Heitzler
V
V
Mihatov
S
S
Vukosavić
D
D
Lukenda
J
J
Radić
B
B
Starcević
B
B
Zigman
M
M
Sharma
M
M
D015906:Angioplasty, Balloon, Coronary; D006352:Heart Ventricles; D006801:Humans; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate; D015912:Thrombolytic Therapy; D016896:Treatment Outcome