title: Selective cleavage of Cbz-protected amines.
abstract: Under conditions of catalytic Ni(0) and in most cases just over 1 equiv of Me(2)NH.BH(3)/K(2)CO(3) or Cs(2)CO(3), a Cbz-protected nitrogen, which is part of a heteroaromatic ring, can be chemospecifically cleaved without affecting a Cbz group on an originally basic amine. [reaction: see text]
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106, USA. lipshutz@chem.ucsb.edu
authors.forename: B H
authors.initials: BH
authors.lastname: Lipshutz
authors.forename: S S
authors.initials: SS
authors.lastname: Pfeiffer
authors.forename: A B
authors.initials: AB
authors.lastname: Reed