title: Different measures for assessing stroke outcome: an analysis from the International Stroke Trial in Italy.
abstract: OBJECTIVE
  We sought to assess the relationship between 2 simple questions on recovery (question 1: do you feel that you have made a complete recovery from your stroke?) and dependency (question 2: do you require help from another person for everyday activities?) and the Barthel Index (BI) and Oxford Handicap Scale (OHS), as well as the relationship between BI and OHS, in a large number of Italian stroke survivors who participated in the International Stroke Trial (IST).
  
  
  METHODS
  We used data from 2423 patients interviewed by telephone at 6 months after the event. The kappa statistic, sensitivity, and specificity were calculated for several comparisons. Internal consistency for BI was calculated.
  
  
  RESULTS
  The reliability of the dependency question compared with BI=20 (kappa=0.93) and the reliability of the recovery question compared with OHS=0 (kappa=0.89) were good. Sensitivity of the dependency question in predicting whether patients scored BI >18 was 0.98; sensitivity of the recovery question in predicting whether patients scored OHS=0 was 0.99. The reliability of BI=20 compared with OHS <3 was good (kappa=0.87). Internal consistency of BI was very high (Cronbach's alpha=0.96).
  
  
  CONCLUSIONS
  The 2 simple questions are a good means of evaluating outcome from a patient's view and of dichotomizing the stroke survivor in a time-effective and reliable way.
authors.affiliation: Servizio Malattie Cerebrovascolari, USL 2, Perugia, Italy. istitaly@unipg.it
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Celani
authors.forename: Teresa Anna
authors.initials: TA
authors.lastname: Cantisani
authors.forename: Enrico
authors.initials: E
authors.lastname: Righetti
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Spizzichino
authors.forename: Stefano
authors.initials: S
authors.lastname: Ricci
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D020521:Stroke / Q000175:diagnosis*; D017741:Survivors