Analysis of pharmacoeconomics of sedation and analgesia.
Intravenous sedation and analgesia are cornerstones of the pharmacologic management of the critically ill, mechanically ventilated adult patient. No conclusive evidence exists to support any single optimal sedative or analgesic regimen in this heterogeneous population. The role of cost effectiveness in the process of selecting a regimen is explored with a review of the literature, followed by proposed cost-effectiveness models and recommendations for the clinical practitioner.
Wittbrodt
E T
ET
Department of Pharmacy Practice and Pharmacy Administration, Philadelphia College of Pharmacy, Philadelphia, Pennsylvania, USA.
D000700:Analgesics / Q000191:economics*; D016292:Procedural Sedation / Q000191:economics*; D003362:Cost-Benefit Analysis; D016527:Drug Costs; D006801:Humans; D006993:Hypnotics and Sedatives / Q000191:economics*; D007362:Intensive Care Units / Q000191:economics* / Q000706:statistics & numerical data; D007902:Length of Stay; D008874:Midazolam / Q000191:economics; D015742:Propofol / Q000191:economics; D012121:Respiration, Artificial
D000700:Analgesics; D006993:Hypnotics and Sedatives; D008874:Midazolam; D015742:Propofol