[Periodontal regeneration enhanced by BMP and GTR technique].
OBJECTIVE
To evaluate the effects of BMP on the repair of animal periodontal defects by using GTR technique.


METHODS
30 experimental mandibular buccal alveolar periodontal defects were produced surgically around premolar and molar teeth in 8 young mongrel dogs. The exposed root surfaces were curetted to remove the periodontal ligament and the cementum. The defects were devided into 3 equal groups (collagen, collagen + BMP, control). The results were examined histologically 1 month and 3 months respectively.


RESULTS
In experimental groups the JE downgrowth was inhibital in the early healing, and the new attachment formation was promoted while comparing with the controls. Compound membrane (with BMP) showed the capacity to support more new bone and cementum formation than the other two groups.


CONCLUSIONS
It is suggested that exogenous BMP can be used in GTR technique to promote periodontal regeneration.
Wang
Q
Q
College of Stomatology, Fourth Military Medical University, Xi'an 710032.
Wu
Z
Z
Shi
J
J
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000494:pharmacology*; D001861:Bone Regeneration / Q000187:drug effects*; D004285:Dogs; D008297:Male; D010519:Periodontium / Q000502:physiology*
D019485:Bone Morphogenetic Proteins