title: Atypical presentation of risperidone toxicity.
abstract: A new class of antipsychotic medication, the "atypical antipsychotics" are gaining popularity. We report 2 cases of toxicity associated with 1 of these new antipsychotics, risperidone. Both patients presented with fatigue, orthostasis, dry mucous membranes, and the unusual finding of miosis. The pathophysiology and clinical presentation of overdose with this agent are discussed.
authors.affiliation: Department of Emergency Medicine at Cook County Hospital, University of Illinois at Chicago, 60612, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Hodge
authors.forename: M
authors.initials: M
authors.lastname: Jewell
authors.forename: D D
authors.initials: DD
authors.lastname: Gummin
authors.forename: J B
authors.initials: JB
authors.lastname: Leikin
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004244:Dizziness / Q000175:diagnosis; D062787:Drug Overdose / Q000175:diagnosis; D005221:Fatigue / Q000139:chemically induced; D005260:Female; D006801:Humans; D015877:Miosis / Q000139:chemically induced*; D009092:Mucous Membrane / Q000473:pathology; D018967:Risperidone / Q000009:adverse effects*
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone