Progress in HIV vaccine development.
Recent advances in HIV vaccine development include initiation of the first efficacy trials and substantial expansion of the preclinical pipeline. Several preclinical candidate vaccines have induced strong cellular immune responses and provided impressive protection against AIDS in non-human primate models; however, candidates that induce broadly neutralizing antibodies remain elusive.
Johnston
M I
MI
Division of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-7628, USA. pjohnston@niaid.nih.gov
Flores
J
J
D016915:AIDS Vaccines / Q000009:adverse effects / Q000138:chemical synthesis / Q000627:therapeutic use*; D000818:Animals; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data / Q000639:trends*; D004353:Drug Evaluation, Preclinical / Q000706:statistics & numerical data / Q000639:trends*; D015658:HIV Infections / Q000188:drug therapy / Q000821:virology; D006801:Humans; D013678:Technology, Pharmaceutical / Q000639:trends
D016915:AIDS Vaccines