title: Modified synthesis of 11-[14C]-clozapine.
abstract: The reported synthetic pathway of 8-chloro-11-(4-methyl-1-piperazinyl)-11-[14C]-5H-dibenzo[b,e][1,4]diazapine (clozapine) was modified in several steps. The synthetic pathway was shortened by 60% and the total yield was increased from 6% to 23%.
authors.affiliation: Nuclear Research Center/AEOI, Chemical Division, Tehran, Iran. hmatloubi@seai.neda.net.ir
authors.forename: H
authors.initials: H
authors.lastname: Matloubi
authors.forename: M
authors.initials: M
authors.lastname: Ghandi
authors.forename: M R
authors.initials: MR
authors.lastname: Zarrindast
authors.forename: N
authors.initials: N
authors.lastname: Saemian