Primary malignant melanoma arising in a cystic necrotic ovarian teratoma.
Cystic ovarian teratomas are common tumours. Malignant melanoma developing in a teratoma, however, is an extremely rare diagnosis. To date, only 24 cases have been reported in the literature. A 56-year-old patient underwent laparotomy for an ovarian tumour. Histopathologic examination revealed a primary malignant melanoma within a cystic necrotic teratoma, possibly arising from uveal cells. An extraovarian primary melanoma could not been found. After 7 months of operation metastasis to the vertebral column occurred, 2 months later liver metastases were diagnosed. The patient died of the disease 14 months after initial diagnosis.
Moehrle
M
M
Department of Dermatology, University of Tuebingen, Liebermeisterstr 25, 72076, Tübingen, Germany. matthias.moehrle@med.uni-tuebingen.de
Fischbach
H
H
Nuessle
B
B
Rassner
G
G
D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D013724:Teratoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery