title: [Disseminated intravascular coagulation(DIC)].
abstract: Disseminated intravascular coagulation (DIC) remains a multifaced syndrome, which may develop with different background and aetiology into venous thromboembolism (mainly chronic, paraneoplastic DIC) or into severe bleeding, factor consumption, thrombocytopenia (i.e. gynaecological acute DIC) or may appear as microthrombotic organ hypoperfusion, organ-failure and necrosis (septic DIC variant). The understanding and consideration of pathogenetic events promotes better identification and interpretation of DIC syndrome and its categories, render more adequate diagnostics and therapy available. The vast majority of new data accumulated in the septic type of DIC, and this general review also tries to put the major emphasis on sepsis-DIC link, laboratory diagnosis and apparent new therapeutic approaches.
authors.affiliation: Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Orvostudományi Kar II. Belgyógyászati Klinika.
authors.forename: M
authors.initials: M
authors.lastname: Udvardy
mesh_terms: D000208:Acute Disease; D002908:Chronic Disease; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism / Q000628:therapy; D006801:Humans; D011379:Prognosis
vernacular_title: Disszeminált intravascularis coagulatio (DIC).