[Lipid lowering treatment of patients with atherosclerotic disease of the lower extremities].
Patients with critical peripheral ischaemia have a significant mortality rate of up to 50% within 4-5 years of surgical vascular reconstruction. This poor survival rate is due to concomitant coronary and cerebrovascular atherosclerotic disease. Large randomised trials have shown that dyslipidaemia is easily modifiable in patients both with and without established coronary artery disease, with significant reductions in cardiovascular morbidity and mortality. Although none of these trials directly measured peripheral vascular status, there is every indication that conclusions submitted for patients with ischaemic heart disease can be translated to patients with peripheral arterial disease (PAD). The object of this review was therefore to divulge the current evidence available, which supports active treatment of dyslipidaemia in patients with PAD.
Bismuth
J
J
Amtssygehuset i Gentofte, karkirurgisk afdeling B. jbismuth@yahoo.com
Kofoed
S C
SC
Sillesen
H H
HH
D001161:Arteriosclerosis / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D003327:Coronary Disease / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D019317:Evidence-Based Medicine; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D007511:Ischemia / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D007866:Leg / Q000098:blood supply*; D016491:Peripheral Vascular Diseases / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D012307:Risk Factors
D000960:Hypolipidemic Agents
Lipidsaenkende behandling af patienter med aterosklerotisk sygdom i underekstremiteterne.