[Structural and functional changes in various cells following radiation exposure].
Structural and functional changes in thymocytes, splenocytes and hepatocytes, taking place under gamma-irradiation of cellular suspensions were investigated. It was found that splenocytes begin to lose their functional activity and structural features at a dose of 2 Gy. Increasing the irradiation dose leads to the acceleration of these processes. Thymocytes lose rapidly their functional activity at 2 Gy, but they maintain their structure and membrane parameters even after irradiation with a dose of 10 Gy. In comparison with other cell types, hepatocytes exhibit the greatest stability under the influence of gamma-radiation.
Paranich
A V
AV
Karazin Khar'kov National University, Khar'kov, Ukraine.
Tyslenko
K V
KV
Frolova
N A
NA
Grigorovich
A V
AV
Doroshenko
A O
AO
Roshal'
A D
AD
Aldabaev
Iu V
IuV
Zakrevskiĭ
D I
DI
Svetlakova
N N
NN
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D022781:Hepatocytes / Q000378:metabolism / Q000528:radiation effects*; D066298:In Vitro Techniques; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000378:metabolism; D009928:Organ Specificity; D051381:Rats; D013154:Spleen / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects*; D013950:Thymus Gland / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects*; D024505:Tocopherols / Q000378:metabolism
D008315:Malondialdehyde; D024505:Tocopherols
Strukturno-funktsional'nye izmeneniia v kletkakh razlichnykh tipov posle radiatsionnogo vozdeĭstviia.