title: [Nitrogen oxide in the pathogenesis of glaucoma and cataract].
abstract: The content of nitrite (final metabolite of nitroradical) was measured in aqueous humor of patients with glaucoma and cataract. The level of NO formation is increased at the initial stage of glaucoma and decreases with the disease progress. A direct correlation between the level of nitrite in aqueous humor and coefficient of easiness of its discharge was detected. Cataract is associated with a high level of nitrite in intraocular fluid. The results are discussed from the viewpoint of ocular hydro--and hemodynamic regulation and NO involvement in the free radical oxidation reactions, playing an important role in the pathogenesis of both diseases.
authors.forename: N I
authors.initials: NI
authors.lastname: Kurysheva
authors.forename: I K
authors.initials: IK
authors.lastname: Tomilova
authors.forename: E L
authors.initials: EL
authors.lastname: Kadykova
authors.forename: A I
authors.initials: AI
authors.lastname: Deev
authors.forename: S B
authors.initials: SB
authors.lastname: Nazarov
authors.forename: N D
authors.initials: ND
authors.lastname: Nagornova
authors.forename: V P
authors.initials: VP
authors.lastname: Artamonov
mesh_terms: D000328:Adult; D000368:Aged; D001082:Aqueous Humor / Q000737:chemistry*; D002386:Cataract / Q000209:etiology* / Q000378:metabolism; D005260:Female; D005609:Free Radicals; D005901:Glaucoma / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009573:Nitrites / Q000032:analysis*; D009589:Nitrogen Oxides / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D005609:Free Radicals; D009573:Nitrites; D009589:Nitrogen Oxides
vernacular_title: Oksid azota v patogeneze glaukomy i katarakty.