title: An efficient synthesis of morpholin-2-one derivatives using glycolaldehyde dimer by the Ugi multicomponent reaction.
abstract: A new one-pot procedure for the efficient synthesis of novel 3-substituted morpholin-2-one-5-carboxamide derivatives using commercially available glycolaldehyde dimer as a bifunctional component with various alpha-amino acids and isocyanides by the Ugi five-center three-component reaction (U-5C-3CR) was developed. [reaction: see text]
authors.affiliation: Biochemicals Research Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea.
authors.forename: Y B
authors.initials: YB
authors.lastname: Kim
authors.forename: E H
authors.initials: EH
authors.lastname: Choi
authors.forename: G
authors.initials: G
authors.lastname: Keum
authors.forename: S B
authors.initials: SB
authors.lastname: Kang
authors.forename: D H
authors.initials: DH
authors.lastname: Lee
authors.forename: H Y
authors.initials: HY
authors.lastname: Koh
authors.forename: Y
authors.initials: Y
authors.lastname: Kim