Diabetic cataract of the musk shrew (Suncus murinus, Insectivora) exhibiting spontaneous non-insulin dependent diabetes mellitus (NIDDM).
The EDS colony, developed as a new laboratory colony of the musk shrew, is characterized by a high incidence of early-onset spontaneous non-insulin dependent diabetes mellitus (NIDDM). In this colony, a few diabetic shrews exhibited a cataract at 1 month after the onset of diabetes, and all diabetic shrews had bilateral cataracts at 5 months after the onset of diabetes. In contrast, cataractous animals were never observed among non-diabetic shrews. These results suggest that the cataract in the EDS colony is a diabetic complication.
Ohno
T
T
Institute for Laboratory Animal Research, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
Kitoh
J
J
Tanaka
S
S
Nishimura
M
M
Namikawa
T
T
D000818:Animals; D000830:Animals, Laboratory; D002386:Cataract / Q000453:epidemiology / Q000209:etiology* / Q000662:veterinary*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000662:veterinary*; D004195:Disease Models, Animal; D005260:Female; D015994:Incidence; D008297:Male; D012788:Shrews; D013997:Time Factors