Bacterial contamination of blood components.
Despite considerable advances in the safety of blood components, transfusion associated bacterial infection (TABI) remains an unresolved problem. As yet there are no perfect preventative, screening and/or detection methodologies for eliminating contaminated units. Until a practical, rapid, cost-effective and logistically acceptable test becomes available, we should be satisfied with the choice of various limited solutions that at least partially improve the bacterial safety of blood components. It is also necessary to establish standardised guidelines and agreed upon systematic procedures for the recognition and reporting of the laboratory and clinical evaluation of adverse reactions in recipients of contaminated blood components.
Seghatchian
J
J
National Blood Service, London & SE, Colindale, UK. jerhard.seghatchian@nbs.nhs.uk
D016470:Bacteremia / Q000517:prevention & control / Q000635:transmission; D001419:Bacteria / Q000302:isolation & purification*; D001431:Bacteriological Techniques / Q000191:economics; D001769:Blood / Q000382:microbiology*; D001771:Blood Banks / Q000191:economics / Q000592:standards; D001793:Blood Preservation; D001803:Blood Transfusion / Q000191:economics; D004866:Equipment Contamination; D006801:Humans; D007962:Leukocytes; D018962:Phlebotomy; D011785:Quality Assurance, Health Care; D012449:Safety; D012680:Sensitivity and Specificity; D012867:Skin / Q000382:microbiology; D065227:Transfusion Reaction; D006113:United Kingdom