title: [A study of Humphrey three zone screening to detect visual field of the patients with pituitary macroadenomas].
abstract: OBJECTIVE
  To evaluate the clinical application of Humphrey three zone screening in detecting the visual field of the patients with pituitary macroadenomas (PMA).
  
  
  METHODS
  There were two groups in the study. The PMA group: 128 PMA cases were selected who had symptoms of visual problem and been diagnosed with computer tomography (CT) or magnetic resonance (MR) and without apparent opacity of refractive medium. The low myopia group: thirty cases with low myopia and without other eye diseases were included. Humphrey three zone screening method was used to detect the 76-points in the central 30 degree visual fields of the patients of the two groups.
  
  
  RESULTS
  In PMA group, 99.2% of the 128 patients and 87.1% of their eyes had visual field defect. 86.7% of the patients had the visual field defect mainly located at the temporal side and showed or tended to have a medial vertical limit. In detecting abnormality of the patients, three zone screening test had a sensitivity of 99.2% (percent of cases with true visual field defect identified by the field test). The mean test duration of each eye is (5.8 +/- 2.2) minutes. In low myopia group, two eyes of two patients had visual field defect. In testing the normal group, three zone screening test had a specificity of 93.3% (percent of cases without true visual field defect appropriately identified by the field test).
  
  
  CONCLUSIONS
  Humphrey three zone screening has very high sensitivity and specificity in detecting visual field, and it is simple, fast and practical for detecting the visual field of the patients with PMA. It plays an important role in implying diagnosis and avoiding misdiagnosis of PMA.
authors.affiliation: Department of Ophthalmology, Second Affiliated Hospital, Guangzhou Medical College, Guangzhou 510260, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Fang
authors.forename: Q
authors.initials: Q
authors.lastname: Huang
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000236:Adenoma / Q000150:complications*; D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications*; D014786:Vision Disorders / Q000150:complications / Q000175:diagnosis*; D014792:Visual Acuity; D014794:Visual Fields