[Morphometrical and immunohistochemical characteristics of the vascular component of the communication systems in the central and peripheral zones of breast cancer nodes before and after radiation therapy].
Communicative systems are involved in morphogenesis of breast cancer. Intensive local irradiation, on the one hand, results in the death of a part of tumor cells in the central zones of breast tumor node. On the other hand, it stops local immune and, consequently, cytolytic reactions in the periarteriolar zones and inhibits these reactions in the pericapillary zones. Therefore, tumor cells in these zones survive and may proliferate.
Golubev
O A
OA
Smolensk Regional Institute of Pathology, 214018, Smolensk.
D000328:Adult; D001943:Breast Neoplasms / Q000098:blood supply* / Q000473:pathology* / Q000532:radiotherapy; D002455:Cell Division; D002470:Cell Survival; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000276:immunology / Q000473:pathology* / Q000532:radiotherapy; D013601:T-Lymphocytes / Q000473:pathology / Q000528:radiation effects
D007070:Immunoglobulin A
Morfometricheskaia i immunogistokhimicheskaia kharakteristika sosudistogo komponenta kommunikatsionnykh sistem v tsentral'nykh i perifericheskikh zonakh opukholevykh uzlov raka molochnoĭ zhelezy do i posle luchevoĭ terapii.