[A clinical prospective study on maternal-fetal transfusion transmitted virus infection].
OBJECTIVE
To observe the transfusion transmitted virus (TTV) infection rate in gravidas and parturients, and explore the route of maternal-fetal transmission.


METHODS
TTV infection was detected by nest-polymerase chain reaction (n-PCR) in the serum of 60 healthy gravidas and parturientes. Once parturient infection was identified, the latices and the umbilical blood were examined for TTV infection as well. Meanwhile, a group of non-pregnant healthy women was tested as control.


RESULTS
The infection rate of observation group was 28.33%, while in the control group it was 7.57%. The difference of the two groups was significant (P < 0.001). Of the TTV positive parturientes, TTV infection rate of their latices was 27.27%, but none of the umbilical blood samples showed TTV positive.


CONCLUSIONS
The TTV infection rate of gravidas and parturientes is higher than that of non-pregnant healthy women. TTV can infect newborns through latices, however, there is no vertical maternal-fetal transmission.
Chen
H
H
Department of Gynecology and Pediatrics, 175th Hospital of People's Liberation Army, Zhangzhou, Fujian Province 363000, China.
Wang
Y
Y
Pei
F
F
D004266:DNA Virus Infections / Q000635:transmission*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008895:Milk, Human / Q000821:virology; D011247:Pregnancy; D011446:Prospective Studies; D022783:Torque teno virus