microRNAs: tiny regulators with great potential.
Animal genomes contain an abundance of small genes that produce regulatory RNAs of about 22 nucleotides in length. These microRNAs are diverse in sequence and expression patterns, and are evolutionarily widespread, suggesting that they may participate in a wide range of genetic regulatory pathways.
Ambros
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Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA. vra@dartmouth.edu
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics; D005786:Gene Expression Regulation; D016678:Genome; D035683:MicroRNAs; D016372:RNA, Antisense / Q000235:genetics*; D022661:RNA, Untranslated / Q000235:genetics*
D035683:MicroRNAs; D016372:RNA, Antisense; D022661:RNA, Untranslated