title: Clinical and radiographic evaluation of periodontal therapy using enamel matrix derivative (Emdogain).
abstract: The aim of the present study was to evaluate clinical and radiographic outcome following the application of enamel matrix derivative--Emdogain in the treatment of the bone defects due to periodontitis. The study included 25 generally healthy patients with advanced periodontitis. Clinical and radiographic examination was carried out twice: before the procedure and a year after treatment. The following clinical parameters were evaluated: probing pocket depth (PPD), clinical attachment level (CAL) and gingival recession (GR). Defect depth, width and bone defect fill were assessed on the radiographs. A year after surgery the follow-up examination found a significant improvement of clinical parameters. The mean depth of gingival pockets was reduced from 8.76 +/- 1.74 mm to 4.52 +/- 1.56 mm. The mean CAL value was also decreased from 10.72 +/- 1.56 mm to 7.82 +/- 1.68 mm. Analysis of radiographs showed a statistically significant reduction in depth and width of bone defects. Our results indicate a good clinical and radiographic effect following the application of Emdogain in the treatment of periodontal intrabony defects.
authors.affiliation: Department of Conservative Dentistry, Medical Academy of Białystok, Białystok, Poland.
authors.forename: M D
authors.initials: MD
authors.lastname: Pietruska
authors.forename: J K
authors.initials: JK
authors.lastname: Pietruski
authors.forename: W
authors.initials: W
authors.lastname: Stokowska
mesh_terms: D000328:Adult; D001861:Bone Regeneration / Q000187:drug effects; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D011859:Radiography
chemical_list: D003746:Dental Enamel Proteins; C109069:enamel matrix proteins