Cloning, mapping and expression analysis of C15orf4, a novel human gene with homology to the yeast mitochondrial ribosomal protein Ym130 gene.
We have identified C15orf4, a novel human gene showing homology to the yeast mitochondrial ribosomal protein YmL30. C15orf4 encodes a transcript of 1,006 nt with an ORF of 279 amino acids and a predicted protein size of 31.7 kDa. Expression of C15orf4 is enriched in testis. C15orf4 was positioned to chromosome 15q24 by radiation hybrid mapping. We have identified the C15orf4 mouse orthologue as well as homologues in other species.
Carim-Todd
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L
Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Hospital Duran i Reynals, Avda Gran Via s/n, km 2,7 L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Sumoy
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L
Andreu
N
N
Estivill
X
X
Escarceller
M
M
D000595:Amino Acid Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D005800:Genes, Fungal; D006801:Humans; D024101:Mitochondrial Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D009928:Organ Specificity; D012269:Ribosomal Proteins / Q000235:genetics*; D016415:Sequence Alignment; D017385:Sequence Homology
C453839:MRPL46 protein, human; D024101:Mitochondrial Proteins; D012269:Ribosomal Proteins