title: Evaluation of interaction between valproate and baclofen in the formalin test in mice.
abstract: Valproate and baclofen dose-dependently inhibited both phases of the formalin test. Combination of valproate and baclofen exerted the additive antinociceptive effect on both phases of the formalin test.
authors.affiliation: Second University Department of Anaesthesiology and Intensive Therapy, Medical University, Lublin, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Czuczwar
authors.forename: J
authors.initials: J
authors.lastname: Kiś
authors.forename: M
authors.initials: M
authors.lastname: Swiader
authors.forename: W A
authors.initials: WA
authors.lastname: Turski
authors.forename: K
authors.initials: K
authors.lastname: Przesmycki
mesh_terms: D000818:Animals; D001418:Baclofen / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D018682:GABA Agents / Q000494:pharmacology; D051379:Mice; D010147:Pain Measurement / Q000187:drug effects*; D017288:Pain Threshold / Q000187:drug effects*; D014635:Valproic Acid / Q000494:pharmacology*
chemical_list: D018682:GABA Agents; D014635:Valproic Acid; D001418:Baclofen