title: Effect of sevoflurane on electrocorticogram in normal brain.
abstract: To clarify the epileptogenicity of sevoflurane, electrocorticograms were monitored in seven patients with unruptured cerebral aneurysm under sevoflurane anesthesia. They had no history of epilepsy or other complications. Spike activities on electrocorticography were seen in all seven patients at 3.3% end-tidal sevoflurane. These results suggest that further study is required to evaluate the suitability of sevoflurane for neurosurgical procedures.
authors.affiliation: Department of Neuroanesthesia, Kohnan Hospital, Sendai, Japan.
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Sato
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shamoto
authors.forename: Masato
authors.initials: M
authors.lastname: Kato
mesh_terms: D000368:Aged; D018685:Anesthetics, Inhalation / Q000009:adverse effects / Q000494:pharmacology*; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology*; D004569:Electroencephalography / Q000187:drug effects*; D004827:Epilepsy / Q000139:chemically induced / Q000503:physiopathology; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery; D007432:Intraoperative Period; D008297:Male; D008738:Methyl Ethers / Q000009:adverse effects / Q000494:pharmacology*; D008875:Middle Aged; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane