title: [Septic shock with liver abscess in an immunocompetence patient. Presentation of an unusual Fusobacterium nucleatum infection].
abstract: BACKGROUND
  Fusobacterium septicemia with septic metastasis is a very rare and potentially serous condition when complicated by septic shock. Most cases have been described in patients with humoral immunity disorders and/or severe underlying chronic disease.
  
  
  METHODS
  A 24-year-old immunocompetent woman with a tonsil infection developed F. nucleatum septic shock with liver abscess formation. Outcome was rapidly favorable with antibiotic treatment and adapted intensive care, probably favored by the absence of an associated immune deficit.
  
  
  CONCLUSIONS
  Despite its low incidence, F. nucleatum should be entertained as a possible cause of septicemia originating from a pelviperitoneal, pulmonary with abscess formation, or upper airway infection. Proper diagnosis is essential due to the risk of poor prognosis. Fusobacterium nucleatum is a commensal strictly anaerobic bacteria of the buccal cavity. It can cause dental and upper airway infections. Septicemia with secondary localization of F. nucleatum is very rare and the severity depends on the presence of associate septic shock. The immunopathological implications of these infections remain to be elucidated.
authors.affiliation: Service de réanimation infectieuse, Hôpital Bichat, 46 rue H. Huchard, F75018 Paris.
authors.forename: N
authors.initials: N
authors.lastname: Mémain
authors.forename: K
authors.initials: K
authors.lastname: Arvaniti
authors.forename: F
authors.initials: F
authors.lastname: Bruneel
authors.forename: C
authors.initials: C
authors.lastname: Leport
authors.forename: M
authors.initials: M
authors.lastname: Wolff
authors.forename: B
authors.initials: B
authors.lastname: Regnier
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D005674:Fusobacterium Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D016967:Fusobacterium nucleatum / Q000302:isolation & purification / Q000472:pathogenicity*; D006801:Humans; D007362:Intensive Care Units; D008100:Liver Abscess / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D012772:Shock, Septic / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D014069:Tonsillitis / Q000150:complications
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Choc septique avec abcès hépatiques chez une patiente immunocompétente. Présentation inhabituelle d'infection à Fusobacterium nucleatum.