title: Color encoding of the two-dimensional echocardiograms to analyze the echo texture of thickened mitral leaflets.
abstract: OBJECTIVE
  The visual identification of different brightness of two-dimensional echocardiograms has natural limitations. The aim of this study was to perform a color-encoding technique on the echocardiograms and to evaluate whether the thickened mitral valve due to different etiologies may exhibit different colors and textures.
  
  
  METHODS
  Two-dimensional echocardiograms in parasternal long axis view in late diastole were digitized in 28 patients with thickened mitral valves and 14 age-matched control subjects. These 28 patients included 14 patients with mitral valve prolapse (MVP) and 14 patients with rheumatic change of mitral valve (RMV). The mean gray level of the anterior mitral valve and the skewness of the histogram of gray level distribution of the anterior mitral valve were studied in all cases.
  
  
  RESULTS
  A significantly greater mean gray level of mitral valves in patients with RMV (114 +/- 20, p < 0.001) and lesser mean gray level in patients with MVP (49 +/- 12, p = 0.041) compared to that of control subjects (62 +/- 18) were noted. The mitral valves of the echocardiograms of patients with MVP tended to show a blue-to-green color, while those of RMV tended to show a yellow-to-orange color by this image processing system. Significant differences in skewness of the gray level distribution of mitral valves in control vs RMV (p = 0.001), control vs MVP (p = 0.005), and RMV vs MVP (p < 0.001) were also found.
  
  
  CONCLUSIONS
  This study demonstrates that the thickened mitral valves due to MVP and RMV may exhibit different colors and textures. Digital image processing can provide additional information to conventional echocardiograms in characterizing different echo textures of the heart valves.
authors.affiliation: Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan, Republic of China. sllin@isca.vghks.gov.tw
authors.forename: S L
authors.initials: SL
authors.lastname: Lin
authors.forename: S T
authors.initials: ST
authors.lastname: Young
authors.forename: C P
authors.initials: CP
authors.lastname: Liu
authors.forename: H T
authors.initials: HT
authors.lastname: Chaing
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D018618:Echocardiography, Doppler, Color / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging*; D008945:Mitral Valve Prolapse / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012214:Rheumatic Heart Disease / Q000000981:diagnostic imaging*