Cannabinoids: a real prospect for pain relief?
Research on the therapeutic potential of cannabinoids has grown dramatically over the past few years. Recent advances include evidence that cannabinoid agonists are antihyperalgesic and antiallodynic in models of neuropathic pain. Development of novel cannabinoid agonists and cannabinoid preparations that are antinociceptive has important implications for the therapeutic use of this class of drugs.
Iversen
Leslie
L
Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
Chapman
Victoria
V
D000818:Animals; D002186:Cannabinoids / Q000378:metabolism / Q000627:therapeutic use*; D006801:Humans; D010146:Pain / Q000188:drug therapy* / Q000378:metabolism; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug / Q000819:agonists / Q000037:antagonists & inhibitors / Q000502:physiology
D002186:Cannabinoids; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug