title: Fat-soluble vitamin status is not affected by diacylglycerol consumption.
abstract: OBJECTIVE
  The objective of this study was to examine the effect of dietary diacylglycerol (DAG) on the bioavailability of fat-soluble vitamins in comparison with triacylglycerol (TAG).
  
  
  METHODS
  We conducted a long-term administration test of DAG and TAG in 27 healthy men aged 27-47 years. After measuring baseline values, subjects were randomized into two groups, one group (n = 15) was given DAG and the other (n = 12) was given TAG. Subjects ingested 20 g of DAG or TAG either in mayonnaise or an emulsion drink of their own choice at meals once a day for 12 weeks. At 4, 8 and 12 weeks, fasting blood samples were drawn and serum levels of vitamin A, E, and D were measured.
  
  
  RESULTS
  There were no significant changes in vitamin A levels throughout the study period. Compared to the initial values (using a Student's t test for paired values), significant differences of vitamin E and D were seen at some points during the experiment. According to a two-way repeated measures analysis of variance, however, DAG and TAG (lipid) and time had no effect on fat-soluble vitamin levels.
  
  
  CONCLUSIONS
  Our results indicate that DAG does not affect the absorption of the fat-soluble vitamins in diets.
authors.affiliation: Biological Science Laboratories, Kao Corporation, 2606, Akabane, Ichikai-machi, Haga-gun, Tochigi 321-3497, Japan. 306945@kastanet.kao.co.jp
authors.forename: H
authors.initials: H
authors.lastname: Watanabe
authors.forename: K
authors.initials: K
authors.lastname: Onizawa
authors.forename: S
authors.initials: S
authors.lastname: Naito
authors.forename: H
authors.initials: H
authors.lastname: Taguchi
authors.forename: N
authors.initials: N
authors.lastname: Goto
authors.forename: T
authors.initials: T
authors.lastname: Nagao
authors.forename: N
authors.initials: N
authors.lastname: Matsuo
authors.forename: I
authors.initials: I
authors.lastname: Tokimitsu
authors.forename: T
authors.initials: T
authors.lastname: Yasukawa
authors.forename: R
authors.initials: R
authors.lastname: Tsushima
authors.forename: H
authors.initials: H
authors.lastname: Shimasaki
authors.forename: H
authors.initials: H
authors.lastname: Itakura
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001682:Biological Availability; D004075:Diglycerides / Q000008:administration & dosage*; D004311:Double-Blind Method; D006801:Humans; D007408:Intestinal Absorption; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D014280:Triglycerides / Q000008:administration & dosage*; D014801:Vitamin A / Q000097:blood / Q000493:pharmacokinetics*; D014807:Vitamin D / Q000097:blood / Q000493:pharmacokinetics*; D014810:Vitamin E / Q000097:blood / Q000493:pharmacokinetics*
chemical_list: D004075:Diglycerides; D014280:Triglycerides; D014801:Vitamin A; D014807:Vitamin D; D014810:Vitamin E