title: Spare post-exposure prophylaxis with round-the-clock HIV testing of the source patient.
abstract: After occupational exposures, immediate HIV testing of source patients may avoid the unnecessary use of post-exposure prophylaxis (PEP). Two time periods were compared. Before the availability of 24 h a day immediate testing, PEP was initiated after 12.6% of exposures, compared with 3.7% during the second period. The adjusted relative odds ratio of PEP during the second compared with the first period, was 0.23. The availability of immediate HIV testing limits unnecessary occupational PEP.
authors.affiliation: Division of Infectious Diseases, University Hospital, Lausanne, Switzerland.
authors.forename: G
authors.initials: G
authors.lastname: Greub
authors.forename: A
authors.initials: A
authors.lastname: Maziéro
authors.forename: P
authors.initials: P
authors.lastname: Bürgisser
authors.forename: A
authors.initials: A
authors.lastname: Telenti
authors.forename: P
authors.initials: P
authors.lastname: Francioli
mesh_terms: D015492:AIDS Serodiagnosis; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000175:diagnosis / Q000517:prevention & control* / Q000635:transmission; D006282:Health Personnel; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional; D016273:Occupational Exposure; D010361:Patients; D013997:Time Factors
chemical_list: D015483:HIV Antibodies