Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain).
Extracts from 44 species of seaweed from Gran Canaria (Canary Islands, Spain) were screened for the production of antibacterial and antifungal compounds against a panel of gram-negative and gram-positive bacteria, mycobacteria, yeasts and fungi. A total of 28 species displayed antibacterial activity, of which six also showed antifungal activity. Asparagopsis taxiformis and Cymopolia barbata were the species with the strongest activities against the broadest spectrum of target microorganisms. All the species with antibacterial activity were active against gram-positive bacteria, whereas only two species, A. taxiformis and Osmundea hybrida, were active against mycobacteria. The production of secondary metabolites with antimicrobial activities by the macroalgae was also studied under different conditions, although no common trend for bioactivity was observed.
González del Val
A
A
Center for Basic Research, Merck Research Laboratories, Merck Sharp & Dohme de España, Madrid. ant_gonzalez@merck.com
Platas
G
G
Basilio
A
A
Cabello
A
A
Gorrochategui
J
J
Suay
I
I
Vicente
F
F
Portillo
E
E
Jiménez del Río
M
M
Reina
G G
GG
Peláez
F
F
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D019149:Bioreactors; D004352:Drug Resistance, Microbial; D012624:Seaweed / Q000737:chemistry / Q000145:classification / Q000378:metabolism*; D013030:Spain
D000900:Anti-Bacterial Agents