title: [Perforated peptic ulcers].
abstract: Two hundred forty-eight patients were operated for perforated peptic ulcer between 1983 and 1998. Of the patients 112 (45.1%) had chronic, 34 (13.7%) had acute ulcer history and 102 (41.2%) had no ulcer history. Of the patients 228 (92.0%) had duodenal, 9 (3.6%) had juxtapyloric, 6 (2.4%) had marginal, and 5 (2.0%) had antral ulcer. Forty two patients (16.9%) admitted within 12 hours and 206 patients (83.1%) between 12 hours and six days after perforation. Simple closure and omental patch was performed in 32 patients (12.9%) who had severe concomitant illness and 126 (50.8%) intraabdominal sepsis, truncal vagotomy + pyloroplasty in 32 (12.9%), simple closure + omental patch + truncal vagotomy + gastroenterostomy in 34 (13.7%), simple closure + omental patch + parietal cell vagotomy in 21 (8.5%), truncal vagotomy + antrectomy in 3 (1.2%). Patients who didn't have definitive procedure received H2 receptor blockers or proton pomp inhibitors. One hundred ninety-three patients (77.8%) underwent endoscopic control. Two of 53 patients with definitive procedure (3.8%) and 34 of 140 patients (24.3%) with simple closure had recurrence. Two patients in simple closure group underwent parietal cell vagotomy, the others received medical treatment. The recurrence rate was significantly higher in simple closure group (p < 0.01).
authors.affiliation: Atatürk Universitesi Tip Fakültesi Genel Cerrahi Anabilim Dali, Erzurum. abalik@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Balik
authors.forename: F
authors.initials: F
authors.lastname: Celebi
authors.forename: M
authors.initials: M
authors.lastname: Başoğlu
authors.forename: I
authors.initials: I
authors.lastname: Yildirgan
authors.forename: S
authors.initials: S
authors.lastname: Dalga
authors.forename: K Y
authors.initials: KY
authors.lastname: Polat
authors.forename: D
authors.initials: D
authors.lastname: Oren
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D002648:Child; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000150:complications*; D004638:Emergency Treatment / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000453:epidemiology* / Q000473:pathology / Q000517:prevention & control / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D013276:Stomach Ulcer / Q000150:complications*; D014421:Turkey / Q000453:epidemiology
chemical_list: D000897:Anti-Ulcer Agents