Successful medical treatment of two patients with eosinophilic oesophagitis.
OBJECTIVE
Significant oesophageal eosinophilia is associated with oesophagitis and gastroesophageal reflux (GER). Eosinophilic oesophagitis is a rare disease that causes thickening of the oesophageal wall, narrowing of the oesophageal lumen, and severe motor disturbance.


RESULTS
Two 12 yr-old patients with eosinophilic oesophagitis were studied prospectively. Clinical and investigation details are presented. Elemental formula was administered until complete remission of disease. Final outcome was assessed after 3 months on regular diet with exclusion of specific allergic components. Both patients responded to the dietary manipulation.


CONCLUSIONS
Eosinophilic oesophagitis must be included in the differential diagnosis when dealing with oesophageal strictures of unknown or unclear aetiology. Elimination diet therapy plays a crucial role in ameliorating the course of the illness. Blood eosinophilia correlates with therapeutic response and with improvement of the disease.
De Agustin
J C
JC
Madrid, Spain.
Sanz
N
N
Canals
M J
MJ
Alvarez
E
E
Morales
J L
JL
Soler
J
J
Ollero
J C
JC
Vazquez
J
J
D001466:Barium Sulfate; D002648:Child; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000175:diagnosis / Q000178:diet therapy* / Q000473:pathology; D004940:Esophageal Stenosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000178:diet therapy*; D004941:Esophagitis / Q000000981:diagnostic imaging / Q000178:diet therapy* / Q000473:pathology; D004947:Esophagus / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology; D005526:Food, Formulated; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011859:Radiography; D016896:Treatment Outcome
D001466:Barium Sulfate