RWJ-333441 Microcide/RW Johnson.
Microcide and RW Johnson Pharmaceutical Research Institute are investigating a novel cephalosporin prodrug RWJ-333442 for the potential treatment of bacterial infections. RWJ-333442 is the prodrug of RWJ-333441; it has an improved solubility profile and studies are in progress in human serum, rats and rhesus macaques [382578], [382862], [383594].
Jiraskova
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Charles University Hospital, Department of Ophthalmology, Kralove, Czech Republic. kvasnicka@lfhk.cuni.cz
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002511:Cephalosporins / Q000494:pharmacology*; D007769:Lactams; D011355:Prodrugs / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D007769:Lactams; D011355:Prodrugs; C452865:RWJ-333441