Effect of prostaglandin E1 on ophthalmic artery velocimetry in a pre-eclamptic woman with visual disturbance caused by retinal arterial narrowing.
We reported the ophthalmic arterial velocimetry and the effect of prostaglandin E1 on that using color Doppler ultrasonography in a 29-year-old pre-eclamptic woman with postpartum weakness of vision due to retinal arterial narrowing. In this case, we found higher pulsatility index and lower mean velocity than that in normal pregnancy. The 30.8% reduction of ophthalmic artery pulsatility index and 53.9% acceleration of mean velocity were observed at 25 min after intravenous administration of prostaglandin E1. Normalization of these values preceded the recovery of vision. These findings suggest a vasodilated effect of prostaglandin E1 on orbital circulation in a pre-eclamptic woman with weakness of vision due to retinal arterial narrowing.
Ohno
Yasumasa
Y
Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Nagoya, Japan. yasumasa@med.nagoya-u.ac.jp
Kawai
Michiyasu
M
Arii
Yoshitaro
Y
Mizutani
Shigehiko
S
D000328:Adult; D000527:Alprostadil / Q000627:therapeutic use*; D001783:Blood Flow Velocity / Q000187:drug effects; D005260:Female; D006801:Humans; D009880:Ophthalmic Artery / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000150:complications / Q000503:physiopathology*; D011247:Pregnancy; D012161:Retinal Artery / Q000503:physiopathology*; D018615:Ultrasonography, Doppler, Color; D014665:Vasodilator Agents / Q000627:therapeutic use*; D014786:Vision Disorders / Q000188:drug therapy / Q000209:etiology*
D014665:Vasodilator Agents; D000527:Alprostadil