[Delayed effects of ionizing radiation on the skin as a function of dose].
The article contains analysis of experimental and clinical data on delayed effects of different doses of ionizing radiation on the skin which in the row with the bone marrow, lens and other radiosensitive organs and critical tissues is one of the criteria of radiation risk for cosmonauts. According to the existing standard, maximal dose to the skin over the career may not exceed 1200 cSy. However, facts presented in the article testify the necessity to reform the standard since there is high probability of pathology including malignant tumor in delayed period after exposure to 1200 cSy. In view of the available data and present-day international recommendations, the maximal dose to the skin over the space career should not be higher than 600 cSy.
Farber
Iu V
IuV
Shafirkin
A V
AV
D002280:Basal Cell Carcinoma / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011829:Radiation Dosage; D012016:Reference Values; D012878:Skin Neoplasms / Q000209:etiology*