title: [Microcirculation, hemostasis, and hemorheology in influenza and acute respiratory viral infections in patients with hypertension].
abstract: OBJECTIVE
  To study microcirculation (MC), hemostasis (HS) and blood viscosity (BV) in influenza and acute respiratory viral infection (ARVI) in hypertensive patients.
  
  
  METHODS
  The study group consisted of 67 hypertensive patients with influenza or ARVI. 45 influenza and ARVI normotensive subjects served control. HS and BV tests were made, conjunctival biomicroscopy was performed.
  
  
  RESULTS
  Patients with influenza and ARVI in the acute period had distinct perivascular and vascular abnormalities, sludge phenomenon in the majority of postcapillary venules and capillaries. In convalescence microcirculation improved. HS in the acute stage of infections was characterized by fast coagulation, depression of fibrinolysis; in convalescence, a significantly enhanced platelet aggregation was seen. The highest BV occurred at low shift speeds. Hypertensive patients had higher vascular permeability and more severe intravascular changes which presented with disseminated intravascular red cell aggregation, slowing down of blood flow, its partial block. In hypertension there was also significantly higher platelet aggregation, lower disaggregation, higher BV increase in convalescence.
  
  
  CONCLUSIONS
  Hypertensive patients with influenza or ARVI had serious disorders of microcirculation, HS and BV threatening cardiovascular complications in such patients.
authors.forename: B P
authors.initials: BP
authors.lastname: Bogomolov
authors.forename: A V
authors.initials: AV
authors.lastname: Deviatkin
authors.forename: L L
authors.initials: LL
authors.lastname: Efimov
authors.forename: S A
authors.initials: SA
authors.lastname: Mitiushina
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001809:Blood Viscosity; D001991:Bronchitis / Q000097:blood / Q000150:complications / Q000503:physiopathology; D018056:Hemorheology; D006487:Hemostasis; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications / Q000503:physiopathology*; D007251:Influenza, Human / Q000097:blood / Q000150:complications / Q000503:physiopathology; D008833:Microcirculation; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000097:blood* / Q000150:complications / Q000503:physiopathology* / Q000821:virology