Regio- and stereoselective dimerization of terminal alkynes to enynes catalyzed by a palladium/imidazolium system.
A Palladium/imidazolium chloride system has been used to mediate the dimerization of terminal alkynes to enynes. The combination of 1 mol % Pd(OAc)(2) and 2 mol % IMes.HCl in the presence of Cs(2)CO(3) as base shows high activity and high regio- and steroselectivity for the dimerization of aryl and aliphatic terminal alkynes to enynes.
Yang
Chuluo
C
Department of Chemistry, University of New Orleans, New Orleans, Louisiana 70148, USA. snolan@uno.edu
Nolan
Steven P
SP