title: Tree-based linkage and association analyses of asthma.
abstract: Tree-based linkage analyses and association studies are introduced and applied for two data sets on asthma from Genetic Analysis Workshop 12. Consistent and strong evidence of linkage and association to markers on chromosomes 1 and 11 is revealed. Linkage to chromosome 16 in one data set and association with D6S276 in the other data set are also detected.
authors.affiliation: Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut, USA.
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: C P
authors.initials: CP
authors.lastname: Tsai
authors.forename: C Y
authors.initials: CY
authors.lastname: Yu
authors.forename: G
authors.initials: G
authors.lastname: Bonney
mesh_terms: D000328:Adult; D001249:Asthma / Q000453:epidemiology / Q000208:ethnology / Q000235:genetics*; D044383:Black People / Q000235:genetics; D002648:Child; D002874:Chromosome Mapping / Q000706:statistics & numerical data*; D002878:Chromosomes, Human, Pair 1; D002880:Chromosomes, Human, Pair 11; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D014644:Genetic Variation / Q000235:genetics; D005828:Genetics, Population; D005858:Germany; D006801:Humans; D008126:Lod Score; D008297:Male; D008432:Mathematical Computing; D014481:United States; D044465:White People / Q000235:genetics; D001741:Black or African American
chemical_list: D005819:Genetic Markers