title: Primary sclerosing cholangitis complicated with idiopathic thrombocytopenic purpura.
abstract: We present a 66-year-old woman with primary sclerosing cholangitis (PSC) complicated with idiopathic thrombocytopenic purpura (ITP). Both PSC and ITP are considered to reflect an immunological disturbance. However, their coexistence is very rare and to the best of our knowledge this is only the second reported case. In Japan, PSC patients are rarely treated with liver transplantation. Fortunately, the present patient underwent successful hepatic transplantation from a brain-dead donor and simultaneous splenectomy. This case emphasizes the importance of liver transplantation as an effective treatment for primary sclerosing cholangitis.
authors.affiliation: Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Sakai
authors.forename: N
authors.initials: N
authors.lastname: Egawa
authors.forename: H
authors.initials: H
authors.lastname: Sakamaki
authors.forename: M
authors.initials: M
authors.lastname: Sanaka
authors.forename: T
authors.initials: T
authors.lastname: Yuyang
authors.forename: T
authors.initials: T
authors.lastname: Kamisawa
authors.forename: N
authors.initials: N
authors.lastname: Sakaki
authors.forename: N
authors.initials: N
authors.lastname: Funata
authors.forename: Y
authors.initials: Y
authors.lastname: Nakazawa
authors.forename: T
authors.initials: T
authors.lastname: Ikegami
authors.forename: Y
authors.initials: Y
authors.lastname: Hashikura
authors.forename: S
authors.initials: S
authors.lastname: Kawasaki
mesh_terms: D000368:Aged; D001706:Biopsy; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015209:Cholangitis, Sclerosing / Q000150:complications* / Q000276:immunology / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D016031:Liver Transplantation; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000209:etiology*; D013156:Splenectomy; D016896:Treatment Outcome