title: Surgical ventricular reconstruction and mitral regurgitation: what have we learned from 10 years of experience?
abstract: Ischemic mitral regurgitation is functional, and caused predominantly by ventricular dilatation, with secondary functional changes related to annular dilatation, tethering of leaflets from distension, and intraventricular widening between papillary muscles, in the absence of chordal rupture. The treatment includes dealing with the mitral-ventricular interaction by combining surgical ventricular restoration and coronary bypass grafts (CABGs) to alter fiber orientation and muscle nourishment, with annuloplasty, decreasing left ventricle (LV) cavitary volume to reduce abnormal lengthening for tethering, and narrowing the distance between papillary muscles to restore a more normal transverse diameter. These interventions are performed during surgical ventricular restoration (SVR), and the annuloplasty is performed within the ventricle. The cavitary size after SVR must not be restrictive, and methods of patch angulation to restore an elliptic chamber, and interventions to avoid too small a LV cavity are discussed as we summarize 10 years of experience with SVR in 924 patients, and analyze interventions for mitral insufficiency in a recent 3-year subset of 363 patients. The integrated response to the vessel, ventricle, and valve are the central themes of management.
authors.affiliation: San Donato Hospital, Milano, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Menicanti
authors.forename: M
authors.initials: M
authors.lastname: Di Donato
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass / Q000401:mortality; D018618:Echocardiography, Doppler, Color; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000401:mortality; D012720:Severity of Illness Index; D013318:Stroke Volume / Q000502:physiology; D016019:Survival Analysis; D014656:Vascular Surgical Procedures / Q000401:mortality