Diterpenes and other constituents from Croton draco (Euphorbiaceae).
Croton draco (Euphorbiaceae) from Guadalupe, San José, Costa Rica was collected in July 1992 and phytochemically studied (leaves, seeds, wood, bark, sap and flowers separately). Commonly known compounds such as 1-hydroxyjunenol, p-hydroxybenzaldehyde, p-methoxybenzoic acid, 3,4,5-trimethoxycinnamyl alcohol, the coumarin scopoletin, the nor-terpenoids 9-dehydrovomifoliol and 2,3-dihydrovomifoliol were obtained. Taspine, two aporphinic alkaloids, the diterpenes 9(11)-dehydrokaurenic acid, hardwikiic acid, the corresponding new 12-oxo derivative as well as five clerodanes and a phorbol ester were also isolated. Three clerodanes were not previously described and their NMR spectroscopical data and MS fragmentation patterns are reported.
Murillo
R M
RM
Escuela de Química and CIPRONA (Centro de Investigación de Productos Naturales), Universidad de Costa Rica, 2060, Costa Rica. renato@calzada.equi.ucr.ac.cr
Jakupovic
J
J
Rivera
J
J
Castro
V H
VH
D004224:Diterpenes / Q000032:analysis*; D019665:Euphorbiaceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*
D004224:Diterpenes