Chemical constituents and biological activities of Zanthoxylum usambarense.
Bioassay-guided fractionation of the dichloromethane extracts of the roots and the bark of Zanthoxylum usambarense led to the isolation of two physiologically active compounds, i.e. canthin-6-one 1 (fungicide) and pellitorine 4 (insecticide). Together with oxychelerythrine 2, norchelerythrine 3, (+)-sesamin 5 and (+)-piperitol-3,3-dimethylallyl ether 6, they were isolated for the first time from this plant.
He
Weidong
W
Department of Organic Chemistry, Faculty of Agricultural and Applied Biological Sciences, University of Gent, Coupure Links 653, B-9000 Gent, Belgium.
Van Puyvelde
Luc
L
De Kimpe
Norbert
N
Verbruggen
Luc
L
Anthonissen
Kristel
K
Van der Flaas
Mark
M
Bosselaers
Jan
J
Mathenge
Simon G
SG
Mudida
Francis P
FP
D000818:Animals; D002243:Carbolines; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D005659:Fungicides, Industrial / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006793:Houseflies / Q000187:drug effects; D026121:Indole Alkaloids; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009287:Naphthyridines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D026023:Permethrin / Q000494:pharmacology; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D053284:Polyunsaturated Alkamides; D027821:Rutaceae
D002243:Carbolines; D005231:Fatty Acids, Unsaturated; D005659:Fungicides, Industrial; D026121:Indole Alkaloids; D007211:Indoles; D007306:Insecticides; D009287:Naphthyridines; D010936:Plant Extracts; D053284:Polyunsaturated Alkamides; C453379:canthin-6-one; D026023:Permethrin; C008778:pellitorine