Molecular determinants of exocytosis.
Membrane fusion processes occur throughout the cell. Among those, exocytosis of secretory organelles is probably one of the fastest fusion events animal cells can achieve. Structural and functional studies have provided a conceptual framework and a starting point for our mechanistic understanding of how SNARE proteins may contribute to the final step in exocytosis.
Bruns
Dieter
D
Max-Planck-Institute for Biophysical Chemistry, Department of Neurobiology, Am Fassberg 11, 37077 Göttingen, Germany. dbruns@mpibpc.gwdg.de
Jahn
Reinhard
R
D000818:Animals; D005089:Exocytosis / Q000502:physiology*; D006801:Humans; D008561:Membrane Fusion / Q000502:physiology*; D008565:Membrane Proteins / Q000502:physiology*; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins
D008565:Membrane Proteins; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins