title: Benzodiazepine discontinuation difficulties in panic disorder: conceptual model and outcome for cognitive-behavior therapy.
abstract: There is consistent support for the efficacy of cognitive-behavior therapy (CBT) to aid the successful discontinuation of benzodiazepine (BZ) medication in patients with panic disorder, and help these individuals maintain treatment gains while off medication. In this article, we provide a conceptual model for BZ discontinuation difficulties in patients with panic disorder. Outcome studies are reviewed, and are placed in the context of other evidence for the efficacy of CBT in patients with this disorder.
authors.affiliation: Harvard Medical School and Massachusetts General Hospital, 15 Parkman St., Boston, MA 02114, USA. MOTTO@PARTNERS.ORG
authors.forename: M W
authors.initials: MW
authors.lastname: Otto
authors.forename: J J
authors.initials: JJ
authors.lastname: Hong
authors.forename: S A
authors.initials: SA
authors.lastname: Safren
mesh_terms: D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001569:Benzodiazepines; D015928:Cognitive Behavioral Therapy / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D016584:Panic Disorder / Q000523:psychology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines