title: Hemodialysis is as effective as hemoperfusion for drug removal in carbamazepine poisoning.
abstract: Although most authors recommend charcoal hemoperfusion (CHP) for the removal of carbamazepine (CBZ) in acute CBZ poisoning, we present a case where we had the chance to compare CHP with hemodialysis (HD). A 50-year-old white man with normal renal function ingested an unknown quantity of CBZ with lithium. He was dialyzed for 3 h and his serum CBZ level was reduced by 27.7%. Four hours later he also had a 3-hour CHP which further reduced his CBZ level by 25.3%. Therefore we conclude that HD with high-flux dialyzers is at least as effective as CHP for the removal of CBZ from the blood after CBZ intoxication.
authors.affiliation: Cleveland Clinic Florida, Fort Lauderdale, FL 33309, USA. tapolyai@innocent.com
authors.forename: Mihály
authors.initials: M
authors.lastname: Tapolyai
authors.forename: Maureen
authors.initials: M
authors.lastname: Campbell
authors.forename: Kathleen
authors.initials: K
authors.lastname: Dailey
authors.forename: Szilvia
authors.initials: S
authors.lastname: Udvari-Nagy
mesh_terms: D000927:Anticonvulsants / Q000506:poisoning*; D002220:Carbamazepine / Q000506:poisoning*; D002606:Charcoal; D006464:Hemoperfusion; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
chemical_list: D000927:Anticonvulsants; D002606:Charcoal; D002220:Carbamazepine