Determination of antidiabetic activity in Allium cepa (onion) tissue cultures.
Seedling, seedling parts and callus cultures of onion were tested for their antidiabetic activity by feeding the tissue-extracts to diabetic rats. The results indicated much higher antidiabetic activity in callus cultures as compared to natural bulbs of onion. These results may be of pharmaceutical significance since the callus can be used as an alternative source for the isolation of antidiabetic compounds.
Kelkar
S M
SM
Radiation Biology Division, Bhabha Atomic Research Centre, Mumbai, India. kelkar@apsara.barc.ernet.in
Kaklij
G S
GS
Bapat
V A
VA
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000188:drug therapy*; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008297:Male; D019697:Onions / Q000737:chemistry*; D010940:Plant Proteins / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010940:Plant Proteins