Association studies of cytosolic phospholipase A2 polymorphisms and schizophrenia among two independent family-based samples.
An association between the cytosolic phospholipase A2 locus (cPLA2) and schizophrenia has been reported using two polymorphic DNA markers. In an attempt to replicate these results, two independent family-based samples were ascertained from the United States and India (86 and 159 families, respectively). No significant associations were detected in either sample.
Chowdari
K V
KV
Department of Psychiatry, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
Brandstaetter
B
B
Semwal
P
P
Bhatia
T
T
Deshpande
S
S
Reddy
R
R
Wood
J
J
Weinberg
C R
CR
Thelma
B K
BK
Nimgaonkar
V L
VL
D001483:Base Sequence; D044383:Black People / Q000235:genetics; D016009:Chi-Square Distribution; D003600:Cytosol / Q000201:enzymology; D017931:DNA Primers; D005190:Family; D005787:Gene Frequency; D005838:Genotype; D054513:Group IV Phospholipases A2; D006801:Humans; D010741:Phospholipases A / Q000235:genetics*; D054467:Phospholipases A2; D011061:Poly A / Q000235:genetics; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012559:Schizophrenia / Q000201:enzymology / Q000235:genetics*; D014481:United States; D044465:White People / Q000235:genetics; D001741:Black or African American
D017931:DNA Primers; D011061:Poly A; D010741:Phospholipases A; D054513:Group IV Phospholipases A2; D054467:Phospholipases A2