title: Remnant lipoproteins and atherogenesis.
abstract: Remnant lipoproteins are reported to play a causative role in atherogenesis. They consist of chylomicron remnants and very low-density lipoprotein remnants. They are heterogeneous in composition and metabolic pathway and are rapidly taken up from the circulation as soon as they are formed in normal lipid metabolism. These characteristics make it difficult to separate and subsequently analyze remnant lipoproteins. Recently, however, we developed a simple and reliable immunoseparation method to separate remnant lipoproteins, and the cellular mechanism(s) by which they contribute to atherogenesis have been elucidated.
authors.affiliation: Department of Applied Genetics, Medical Research Institute, Tokyo Medical and Dental University, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Kawakami
authors.forename: M
authors.initials: M
authors.lastname: Yoshida
authors.forename: A
authors.initials: A
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: Y
authors.initials: Y
authors.lastname: Yasukochi
authors.forename: K
authors.initials: K
authors.lastname: Shimokado
authors.forename: F
authors.initials: F
authors.lastname: Numano
mesh_terms: D001161:Arteriosclerosis / Q000097:blood* / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D008074:Lipoproteins / Q000097:blood* / Q000378:metabolism
chemical_list: D008074:Lipoproteins