Fallopian tube cancer in a BRCA1 mutation carrier: rapid development and failure of screening.
We report a case of fallopian tube cancer that developed in a woman with a germ-line BRCA1 mutation. The notable feature of this case was the extremely rapid growth of the cancer, which precluded early diagnosis. Preventive gynecologic surgery in BRCA1/2 mutation carriers should probably always include bilateral salpingectomy.
Hébert-Blouin
Marie-Noël
MN
Department of Medicine, McGill University Health Centre, McGill University, Montreal, Quebec, Canada.
Koufogianis
Vayia
V
Gillett
Peter
P
Foulkes
William D
WD
D000230:Adenocarcinoma / Q000235:genetics*; D018450:Disease Progression; D005185:Fallopian Tube Neoplasms / Q000235:genetics*; D005260:Female; D019398:Genes, BRCA1; D005820:Genetic Testing; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D010375:Pedigree; D013997:Time Factors