An ocular cat-scratch disease patient positive for cytoplasmic anti-neutrophil cytoplasmic antibody.
BACKGROUND
We report a case of ocular cat-scratch disease with permanent vision reduction in a patient who was cytoplasmic anti-neutrophil cytoplasmic antibody (C-ANCA) positive.


METHODS
Case report and review of the literature.


RESULTS
While taking steroids and antibiotics, a 52-year-old man with uveitis associated with cat-scratch disease developed retinal vein occlusion and a macular exudate. His final visual acuity was poor because of residual macular degeneration and optic atrophy. Serum C-ANCA increased and decreased in parallel with ocular inflammatory activity.


CONCLUSIONS
C-ANCA is an indicator of vasculitis and may be useful as an indicator of severe cat-scratch disease.
Fukushima
H
H
Numaga
J
J
Yoshimoto
M
M
Kato
S
S
Kawashima
H
H
D000667:Ampicillin / Q000627:therapeutic use; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D002372:Cat-Scratch Disease / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy; D004359:Drug Therapy, Combination; D015818:Eye Infections, Bacterial / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009902:Optic Neuritis / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D012170:Retinal Vein Occlusion / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy; D012173:Retinitis / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D014605:Uveitis / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy
D019268:Antibodies, Antineutrophil Cytoplasmic; D015415:Biomarkers; D000667:Ampicillin; D011239:Prednisolone