title: Selective cross-linking to the adenine of the TA interrupting site within the triple helix.
abstract: The triplex-forming oligonucleotide incorporating the new nucleoside derivative (2) that connects the 2-amino-6-vinylpurine moiety to the 2-deoxyribose unit with an ethyl spacer has exhibited highly selective cross-linking reaction to the adenine of the TA interrupting site within the triple helix.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Fumi
authors.initials: F
authors.lastname: Nagatsugi
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Matsuyama
authors.forename: Minoru
authors.initials: M
authors.lastname: Maeda
authors.forename: Shigeki
authors.initials: S
authors.lastname: Sasaki
mesh_terms: D000225:Adenine / Q000737:chemistry*; D020029:Base Pairing / Q000187:drug effects; D003432:Cross-Linking Reagents; D003596:Cytosine / Q000737:chemistry; D003855:Deoxyribose / Q000737:chemistry*; D007202:Indicators and Reagents; D009691:Nucleic Acid Denaturation; D009841:Oligonucleotides / Q000737:chemistry*; D011687:Purines / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: C432203:2-amino-6-vinylpurine; D003432:Cross-Linking Reagents; D007202:Indicators and Reagents; D009841:Oligonucleotides; D011687:Purines; D014753:Vinyl Compounds; D003855:Deoxyribose; D003596:Cytosine; D000225:Adenine