[Pancreatic elastase 1].
Pancreatic elastase 1 is secreted from pancreatic acinar cells as one of the digestive enzymes. Pancreatic elastase 1 is present in serum in a complex formation with alpha 1-antitrypsin, and is measured by immunological methods. Serum pancreatic elastase 1 increases in acute pancreatitis and chronic relapsing pancreatitis. As the serum level remains high for a long period after acute pancreatitis, serum pancreatic elastase 1 is also a tumor marker for the detection of early pancreatic cancer.
Ogawa
M
M
Department of Surgery II, Kumamoto University Medical School.
D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D004796:Clinical Enzyme Tests / Q000379:methods; D006801:Humans; D007841:Latex Fixation Tests; D010196:Pancreatic Elastase / Q000097:blood*; D010190:Pancreatic Neoplasms / Q000175:diagnosis*; D010195:Pancreatitis / Q000175:diagnosis; D011863:Radioimmunoassay
D015415:Biomarkers; D010196:Pancreatic Elastase