title: Megaprepuce associated with vesicoureteric reflux.
abstract: OBJECTIVE
  To describe 4 patients in whom megaprepuce was associated with vesicoureteric reflux (VUR).
  
  
  METHODS
  Four boys aged 6, 4, 5 and 7 months, respectively, presented with dribbling of urine, gross penile swelling and inability to void spontaneously. The first 3 patients had a history of documented urinary tract infection. Micturating cystourethrogram (MCUG) revealed grade III VUR on the right in the first patient, grade V on the left in the second patient, grade III on the right and grade IV in both moieties of left duplex system in the third patient and bilateral grade III in the fourth patient. All patients underwent circumcision.
  
  
  RESULTS
  Follow-up MCUG demonstrated complete resolution of VUR in 2 patients after circumcision. One patient with bilateral VUR showed resolution of VUR on right side but persistence of VUR into the lower moiety of left duplex system after circumcision. Vesicoureteric reflux was downgraded from grade 5 to grade 3 after circumcision in one patient.
  
  
  CONCLUSIONS
  These cases demonstrate for the first time the association of megaprepuce with VUR. VUR associated with megaprepuce is usually resolved after circumcision.
authors.affiliation: National Children's Hospital, Tallaght, Dublin, Ireland.
authors.forename: S
authors.initials: S
authors.lastname: Cascio
authors.forename: E
authors.initials: E
authors.lastname: Colhoun
authors.forename: P
authors.initials: P
authors.lastname: Puri
mesh_terms: D002944:Circumcision, Male; D006801:Humans; D007223:Infant; D008297:Male; D010409:Penile Diseases / Q000150:complications* / Q000601:surgery; D012720:Severity of Illness Index; D014552:Urinary Tract Infections / Q000209:etiology; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis / Q000209:etiology*