Uveitis in a child: masquerade syndrome revisit.
We present a case of relapsing acute lymphoblastic leukemia (ALL) in the anterior chamber, uveitis masquerade syndrome, which was confirmed by anterior chamber paracentesis and aqueous fluid cytology. Three months previously, the patient developed anterior uveitis without hematologic relapse. The uveitis responded well to topical steroid. After anterior chamber paracentesis, bone marrow relapse was detected. High doses of chemotherapy were prescribed. Ocular radiation was planned but the patient developed septicemia and expired. In our opinion, paracentesis should be performed without delay when uveitis develops in ALL, regardless of systemic relapse. Ocular manifestation may be the only sign of leukemic relapse or may present several months prior to systemic relapse.
Atchaneeyasakul
L O
LO
Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Tarinvorakup
P
P
Trinavarat
A
A
Dulayajinda
D
D
Uiprasertkul
M
M
D000287:Administration, Topical; D000970:Antineoplastic Agents / Q000008:administration & dosage; D002648:Child; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017254:Leukemic Infiltration; D019152:Paracentesis; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy; D018570:Risk Assessment; D013256:Steroids / Q000008:administration & dosage; D013577:Syndrome; D014606:Uveitis, Anterior / Q000188:drug therapy* / Q000473:pathology*
D000970:Antineoplastic Agents; D013256:Steroids