Functional analysis of the yeast genome.
Just as Saccharomyces cerevisiae itself provides a model for so many processes essential to eukaryotic life, we anticipate that the methods and the mindset that have moved yeast biological research "beyond the genome" provide a prototype for making similar progress in other organisms. In this review I describe the experimental processes, results and utility of the current large-scale experimental approaches that use genomic data to provide a functional analysis of the yeast genome.
Ross-Macdonald
P
P
Department of Applied Genomics, Bristol-Myers Squibb Pharmaceutical Research Institute, Hopewell, New Jersey, USA.
D018983:DNA Footprinting; D030541:Databases, Genetic; D015180:Electrophoresis, Gel, Two-Dimensional; D020869:Gene Expression Profiling; D016681:Genome, Fungal; D023281:Genomics / Q000379:methods*; D016254:Mutagenesis, Insertional; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000302:isolation & purification; D017422:Sequence Analysis, DNA; D017384:Sequence Deletion; D020798:Two-Hybrid System Techniques
D029701:Saccharomyces cerevisiae Proteins