[Comparative analysis of the level of gene transcription in two types of HIV-associated lymphoma].
In order to characterize the molecular mechanisms of lymphoma formation in HIV-infected humans, a method of two-staged substractive cloning was used, which adequately detects genes whose expression is increased in cells of one lymphoma in comparison with another. Using this method, we determined the spectrum of genes whose expression was increased in centroblastic non-Hodgkin's lymphoma in comparison with immunoblastic non-Hodgkin's lymphoma. Several gene groups were distinguished in this spectrum; their probable involvement in lymphogenesis is discussed.
Nenasheva
V V
VV
Institute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow.
Maksimov
V V
VV
Nikolaev
A I
AI
Tarantul
V Z
VZ
D018076:DNA, Complementary; D020869:Gene Expression Profiling; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000235:genetics*; D008228:Lymphoma, Non-Hodgkin / Q000145:classification / Q000235:genetics*; D014158:Transcription, Genetic
D018076:DNA, Complementary