Efficacy of school urinary screening for membranoproliferative glomerulonephritis type 1.
OBJECTIVE
In order to evaluate the efficacy of a school urinary screening programme, children with membranoproliferative glomerulonephritis (MPGN) type 1 were studied.


METHODS
A total of 52 patients who had been diagnosed with MPGN type 1 from 1970 to 1997 were studied; 35 were identified after 1974 on screening (group S), and 17 were identified by presenting symptoms (group N), mostly before 1989.


RESULTS
Mean blood pressure was 89 mm Hg in group S and 104 mm Hg in group N; urinary protein excretion was 0.9 g/day in group S and 3.0 g/day in group N. Histopathological evidence of chronic changes was found in six group S and 15 group N patients. No patients in group S had renal insufficiency, but five patients in group N required regular haemodialysis.


CONCLUSIONS
Results suggest that early identification by school urinary screening may enable early management and so improve prognosis of MPGN.
Kawasaki
Y
Y
Department of Pediatrics, Fukushima Medical University School of Medicine, Japan. tomo@fmu.ac.jp
Suzuki
J
J
Nozawa
R
R
Suzuki
H
H
D000293:Adolescent; D001706:Biopsy / Q000379:methods; D002648:Child; D005260:Female; D005455:Fluorescent Antibody Technique / Q000379:methods; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications / Q000473:pathology / Q000652:urine*; D006417:Hematuria / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007668:Kidney / Q000473:pathology; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008854:Microscopy, Electron; D009404:Nephrotic Syndrome / Q000209:etiology; D011507:Proteinuria / Q000209:etiology; D016019:Survival Analysis; D016896:Treatment Outcome