title: Potential rebreathing after continuous positive airway pressure failure during sleep.
abstract: BACKGROUND
  Continuous positive airway pressure (CPAP) is widely applied as a home treatment during sleep. Conventional CPAP devices are based on a blower to generate nasal pressure and to maintain air washout from the circuit. Because common CPAP systems do not incorporate alarms, failure in the device or in the electric supply could result in rebreathing.
  
  
  OBJECTIVE
  To assess the potential rebreathing to which a patient could be subjected after CPAP failure.
  
  
  METHODS
  Four conventional CPAP devices, PV100 (Breas Medica; Molnlycke, Sweden), CP90 (Taema; Antony, France), and SoloPlus and BiPAP (Respironics, Murrysville, PA), and three common exhalation ports (Whisper Swivel [Respironics], Plateau [Respironics], and 4-mm orifice) were tested in a bench study. Rebreathing after failure was assessed by measuring the resistance of the exhalation port (REP) and the resistance of the tubing plus CPAP device (RTUB), and by measuring O(2) and CO(2) concentrations in the nasal mask in a subject breathing through a CPAP system.
  
  
  RESULTS
  REP was much higher (approximately 30 cm H(2)O x s/L) than RTUB (approximately 1 cm H(2)O x s/L). Most (approximately 90%) of the breathing tidal volume would flow from/to the tubing plus CPAP device, which represents a dead space (> or = 0.5 L) similar to the patient's tidal volume. After CPAP failure, end-tidal O(2) in the mask changed from 16.8 to 9.2% and end-tidal CO(2) in the mask changed from 4.2 to 6.2%. By contrast, O(2) and CO(2) did not change when a nonrebreathing valve was placed in the mask.
  
  
  CONCLUSIONS
  Common CPAP systems run a risk of inducing rebreathing in case of failure. This risk could be easily avoided by including a passive valve in the apparatus.
authors.affiliation: Unitat de Biofísica i Bioenginyeria, Facultat de Medicina, Universitat de Barcelona, Spain. farre@medicina.ub.es
authors.forename: Ramon
authors.initials: R
authors.lastname: Farré
authors.forename: Josep M
authors.initials: JM
authors.lastname: Montserrat
authors.forename: Eugeni
authors.initials: E
authors.lastname: Ballester
authors.forename: Daniel
authors.initials: D
authors.lastname: Navajas
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008176:Lung Volume Measurements; D008397:Masks; D011175:Positive-Pressure Respiration / Q000295:instrumentation*; D020181:Sleep Apnea, Obstructive / Q000628:therapy*