CT of emphysema.
This article focuses on three main topics: (1) the importance of emphysema as a serious respiratory disease, (2) qualitative assessment of emphysema using CT, and (3) the emerging importance of quantitative CT in the evaluation of patients with emphysema for surgery and drug therapy. CT also can identify the major anatomic subtypes of emphysema. CT is critical in the assessment of patients with the potential for lung volume reduction surgery. CT may well be superior to pulmonary function tests in the longitudinal assessment of current and proposed drug therapies for the treatment of emphysema.
Newell
John D
JD
Department of Radiology, University of Colorado Health Sciences Center, Denver, USA. newellj@njc.org
D000280:Administration, Inhalation; D000284:Administration, Oral; D000368:Aged; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008168:Lung / Q000473:pathology; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D018579:Patient Selection; D010919:Placebos; D011656:Pulmonary Emphysema / Q000145:classification / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000601:surgery; D016032:Randomized Controlled Trials as Topic; D012129:Respiratory Function Tests; D012907:Smoking / Q000009:adverse effects; D014057:Tomography, X-Ray Computed / Q000379:methods; D014212:Tretinoin / Q000627:therapeutic use; D000515:alpha 1-Antitrypsin / Q000008:administration & dosage / Q000627:therapeutic use; D019896:alpha 1-Antitrypsin Deficiency / Q000150:complications
D010919:Placebos; D000515:alpha 1-Antitrypsin; D014212:Tretinoin