title: Surgical outcomes of deep sclerectomy with collagen implant.
abstract: We evaulated the effectiveness and adverse effects of deep sclerectomy with collagen implant (DSCI), which is a kind of nonpenetrating filtering surgery. In this retrospective study, DSCI was performed in 15 eyes of 11 glaucoma patients. An trabeculo-Descemet's membrane (TDM) window is created by a deep sclerokeratectomy, and the collagen implant is placed in the sclera bed under a superficial flap (deep sclerectomy with collagen implant). In 3 of 15 eyes the DSCI was intraoperatively converted to conventional filtering surgery for a large perforation of the TDM. These eyes were not included in the results of the surgical outcomes. The mean age of the patients was 50.3 +/- 14.4 years, and the mean follow-up period was 11.1 +/- 5.9 months. A diagnosis of chronic open angle glaucoma was made in 7 eyes and a diagnosis of secondary glaucoma in 5 eyes. The mean preoperative IOP was 25.8 +/- 11.9 mmHg, the immediate postoperative IOP was 6.4 +/- 2.9 mmHg, and at the final follow-up, the IOP was 11.9 +/- 2.5 mmHg. The IOP in 5 eyes was under 6 mmHg temporarily. However, there was no serious complication such as shallow anterior chamber. DSCI is considered to be a good surgical procedure that has similar surgical outcomes to a conventional trabeculectomy without serious complications.
authors.affiliation: Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: C Y
authors.initials: CY
authors.lastname: Kim
authors.forename: H R
authors.initials: HR
authors.lastname: Chang
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
authors.forename: Y J
authors.initials: YJ
authors.lastname: Hong
mesh_terms: D000328:Adult; D000368:Aged; D003094:Collagen / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005901:Glaucoma / Q000209:etiology / Q000601:surgery*; D005902:Glaucoma, Open-Angle / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures; D019736:Prostheses and Implants; D012189:Retrospective Studies; D012590:Sclera / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D003094:Collagen