title: Rabbitfish ("aras"): an unusual source of ciguatera poisoning.
abstract: BACKGROUND
  Ciguatera poisoning is the commonest fish-borne seafood intoxication. It is endemic to warm water tropical areas and is caused by consumption of bottom-dwelling shore reef fish, mostly during spring and summer. The causative agent, ciguatoxin, is a heat-stable ester complex that becomes concentrated in fish feeding on toxic dinoflagellates. The common clinical manifestations are a combination of gastrointestinal and neurologic symptoms. Severe poisoning may be associated with seizures and respiratory paralysis.
  
  
  OBJECTIVE
  To describe a series of patients who sustained ciguatera poisoning in an uncommon region and from an unexpected source.
  
  
  METHODS
  Two families complained of a sensation of "electrical currents," tremors, muscle cramps, nightmares, hallucinations, agitation, anxiety and nausea of varying severity several hours after consuming rabbitfish ("aras"). These symptoms lasted between 12 and 30 hours and resolved completely. The temporal relationship to a summer fish meal, the typical clinical manifestations along with the known feeding pattern of the rabbitfish suggested ciguatera poisoning.
  
  
  CONCLUSIONS
  The Eastern Mediterranean basin is an unusual region and the rabbitfish an unusual source for ciguatera poisoning. There are no readily available and reliable means for detecting ciguatoxin in humans. A high index of suspicion is needed for diagnosis and a thorough differential diagnosis is essential to eliminate other poisonings, decompression sickness and encephalitis. Supportive therapy is the mainstay of treatment.
authors.affiliation: Israel Poison Information Center, Rambam Medical Center, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
authors.forename: Bianca
authors.initials: B
authors.lastname: Raikhlin-Eisenkraft
authors.forename: Yedidia
authors.initials: Y
authors.lastname: Bentur
mesh_terms: D000328:Adult; D000818:Animals; D001007:Anxiety / Q000139:chemically induced; D002675:Child, Preschool; D036841:Ciguatera Poisoning; D004325:Dreams; D005260:Female; D005400:Fishes, Poisonous; D006212:Hallucinations / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D009120:Muscle Cramp / Q000139:chemically induced; D009325:Nausea / Q000139:chemically induced; D011595:Psychomotor Agitation / Q000209:etiology; D014202:Tremor / Q000139:chemically induced