[A case of eosinophilic myositis proven by immunohistochemistry using antibodies against eosinophilic granule protein].
A 50-year-old man had been well until three months earlier, when he felt general fatigue, and cutaneous rash with itching. Thereafter a general muscular weakness developed and the patient could not walk for a month. Four weeks before referral to our hospital, he had high fever and could not role over in the bed. On admission, the patient was able to walk. He had no skin rash. Neurologically, he showed mild weakness in proximal muscles. Hematologic examination showed mild eosinophilia and serum creatine kinase was mildly elevated. Needle electromyogram revealed a diffuse myogenic pattern in extremities. Eosinophilic myositis was diagnosed by a biopsy of the left calf muscle showing mild infiltration of eosinophilis which was identified using antibodies against eosinophilic granule protein.
Harada
H
H
Department of Neurology, Institute of Clinical Medicine, University of Tsukuba.
Mochizuki
A
A
Ohkoshi
N
N
Tamaoka
A
A
Shoji
S
S
D001323:Autoantibodies / Q000276:immunology*; D001798:Blood Proteins / Q000276:immunology*; D047091:Eosinophil Granule Proteins; D004802:Eosinophilia / Q000150:complications*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D009220:Myositis / Q000175:diagnosis* / Q000473:pathology; D012260:Ribonucleases
D001323:Autoantibodies; D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D012260:Ribonucleases