Single clone bearing chromosomal aberrations in amniotic fluid culture.
We present our data concerning a single clone bearing chromosomal aberration obtained by routine amniocentesis in 2340 parturients. Single clone chromosomal aberrations in amniocytes were more commonly observed in chromosomes 8,18,21,22,X and as supernumeric marker chromosome. No correlation has been found between the incidental chromosomal changes observed in one or two cells of the cultured amniocytes and obstetrical and demographic parameters.
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Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben Gurion University of Negev, Beer-Sheva, Israel. samits@bezeqint.net
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D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology*; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002887:Chromosomes, Human, Pair 18; D002891:Chromosomes, Human, Pair 21; D002892:Chromosomes, Human, Pair 22; D002898:Chromosomes, Human, Pair 8; D002999:Clone Cells / Q000648:ultrastructure*; D005260:Female; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D014960:X Chromosome