title: Fast method for the localisation of current dipoles in the human brain.
abstract: A fast algorithm for localising multiple current dipoles in the human brain by measuring the external magnetic field is presented. A genetic algorithm is used first for rough estimate of locations. To speed up the global optimisation algorithm, an explicit solution for a spherical head model is used for the rough estimation. This rough estimate is then used as a start for a fine search using a gradient-based algorithm, in which a boundary element solution for a realistic brain-shaped head model is used. Numerical simulation indicates that the present algorithm converges three-four times faster than an algorithm using a brain-shaped head model in all the steps.
authors.affiliation: State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, People's Republic of China. lijun@coer.zju.edu.cn
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: H
authors.initials: H
authors.lastname: Zhu
authors.forename: S
authors.initials: S
authors.lastname: He
mesh_terms: D000465:Algorithms; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D004594:Electrophysiology; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods*; D008953:Models, Anatomic