title: Association studies of cytosolic phospholipase A2 polymorphisms and schizophrenia among two independent family-based samples.
abstract: An association between the cytosolic phospholipase A2 locus (cPLA2) and schizophrenia has been reported using two polymorphic DNA markers. In an attempt to replicate these results, two independent family-based samples were ascertained from the United States and India (86 and 159 families, respectively). No significant associations were detected in either sample.
authors.affiliation: Department of Psychiatry, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
authors.forename: K V
authors.initials: KV
authors.lastname: Chowdari
authors.forename: B
authors.initials: B
authors.lastname: Brandstaetter
authors.forename: P
authors.initials: P
authors.lastname: Semwal
authors.forename: T
authors.initials: T
authors.lastname: Bhatia
authors.forename: S
authors.initials: S
authors.lastname: Deshpande
authors.forename: R
authors.initials: R
authors.lastname: Reddy
authors.forename: J
authors.initials: J
authors.lastname: Wood
authors.forename: C R
authors.initials: CR
authors.lastname: Weinberg
authors.forename: B K
authors.initials: BK
authors.lastname: Thelma
authors.forename: V L
authors.initials: VL
authors.lastname: Nimgaonkar
mesh_terms: D001483:Base Sequence; D044383:Black People / Q000235:genetics; D016009:Chi-Square Distribution; D003600:Cytosol / Q000201:enzymology; D017931:DNA Primers; D005190:Family; D005787:Gene Frequency; D005838:Genotype; D054513:Group IV Phospholipases A2; D006801:Humans; D010741:Phospholipases A / Q000235:genetics*; D054467:Phospholipases A2; D011061:Poly A / Q000235:genetics; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012559:Schizophrenia / Q000201:enzymology / Q000235:genetics*; D014481:United States; D044465:White People / Q000235:genetics; D001741:Black or African American
chemical_list: D017931:DNA Primers; D011061:Poly A; D010741:Phospholipases A; D054513:Group IV Phospholipases A2; D054467:Phospholipases A2