[Absorption of fat from three dietary sources in rats with lactose induced diarrhea].
Low energy intake is one the most important factors related to nutritional wasting during diarrheal episodes and fat is the macronutrient with the highest energy value. So we intended to seek dietary fat sources, with the highest bioavailability during diarrheal episodes. Three basal (control) and three 42.8% lactose containing diets, used to induce diarrhea, were prepared with corn oil, butterfat or lard. The assay included 48 Sprague-Dawley rats, 28 d of age, initial weights of 65.5 +/- 5.2 g, distributed in 6 groups that received the diets during 15 d. The different types of fat did not affect diet intake, weight gain or fecal losses in rats without diarrhea (control). Low weight gain was found in rats with diarrhea regardless of the type of fat consumed and was related to low diet consumption. Mean fat absorption during diarrhea was as follows: butterfat 84%, lard 87% and corn oil 91%. The latter was related to lower fecal losses and higher fat absorption during the 15 d study. Considering that the three fat sources evaluated are easily purchased and widely accepted, and that nutritional management of subjects with diarrhea includes the intake of energy dense diets, it seems that the use of corn oil in these formulations could offer greater advantages.
González
E G
EG
Universidad Simón Bolívar, Caracas, Venezuela.
Sanchez
G
G
Cioccia
A M
AM
Hevia
P
P
D000818:Animals; D002079:Butter; D003314:Corn Oil / Q000378:metabolism; D003967:Diarrhea / Q000139:chemically induced / Q000178:diet therapy / Q000378:metabolism*; D004041:Dietary Fats / Q000378:metabolism* / Q000627:therapeutic use; D007408:Intestinal Absorption / Q000502:physiology; D007785:Lactose; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013552:Swine
D004041:Dietary Fats; D003314:Corn Oil; D002079:Butter; D007785:Lactose