title: Genetic analysis of the RcsC sensor kinase from Escherichia coli K-12.
abstract: The Rcs two-component pathway is involved in the regulation of capsule production in Escherichia coli. RcsC is predicted to be the sensor component of this two-component pathway, and in this study we present the first genetic data that support the role of RcsC as a hybrid sensor kinase.
authors.affiliation: Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom. bssdjc@bath.ac.uk
authors.forename: D J
authors.initials: DJ
authors.lastname: Clarke
authors.forename: S A
authors.initials: SA
authors.lastname: Joyce
authors.forename: C M
authors.initials: CM
authors.lastname: Toutain
authors.forename: A
authors.initials: A
authors.lastname: Jacq
authors.forename: I B
authors.initials: IB
authors.lastname: Holland
mesh_terms: D000595:Amino Acid Sequence; D001224:Aspartic Acid / Q000235:genetics / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics; D017124:Conserved Sequence; D004926:Escherichia coli / Q000235:genetics; D029968:Escherichia coli Proteins; D015870:Gene Expression; D005816:Genetic Complementation Test; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins / Q000096:biosynthesis; D006639:Histidine / Q000235:genetics / Q000378:metabolism; D007763:Lac Operon; D008969:Molecular Sequence Data; D009097:Multienzyme Complexes / Q000235:genetics* / Q000378:metabolism; D016296:Mutagenesis; D010749:Phosphoprotein Phosphatases / Q000235:genetics* / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics* / Q000378:metabolism; D011494:Protein Kinases / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D009097:Multienzyme Complexes; C109893:cpsB protein, Streptomyces roseosporus; C489728:rcsC protein, E coli; D001224:Aspartic Acid; D006639:Histidine; D011494:Protein Kinases; D010749:Phosphoprotein Phosphatases; D010744:Phosphoric Monoester Hydrolases