title: Cryphonectric acid and other minor metabolites from a hypovirulent strain of Cryphonectria parasitica.
abstract: Investigations carried out on secondary metabolites produced in culture by a hypovirulent strain of Cryphonectria parasitica allowed the isolation of several compounds which were characterized by NMR analysis and derivatization reactions. The most abundant metabolite was a new compound, called cryphonectric acid (1). Other metabolites were diaporthin, the only known phytotoxic compound isolated from both virulent and hypovirulent strains of C. parasitica, (+)-orthosporin, and L-p-hydroxyphenyllactic acid (HOPLA). Root growth activity of the purified compounds was evaluated both on tomato seedlings and maize subapical segments.
authors.affiliation: Istituto di Patologia Vegetale, Università degli Studi, 20123 Milano, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Arnone
authors.forename: Gemma
authors.initials: G
authors.lastname: Assante
authors.forename: Gianluca
authors.initials: G
authors.lastname: Nasini
authors.forename: Sara
authors.initials: S
authors.lastname: Strada
authors.forename: Annamaria
authors.initials: A
authors.lastname: Vercesi
mesh_terms: D001203:Ascomycota / Q000737:chemistry*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D020128:Inhibitory Concentration 50; D018551:Solanum lycopersicum / Q000187:drug effects / Q000254:growth & development; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010666:Phenylpropionates / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D063245:Plant Development; D018517:Plant Roots / Q000187:drug effects / Q000254:growth & development; D010944:Plants / Q000187:drug effects; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D003313:Zea mays / Q000187:drug effects / Q000254:growth & development
chemical_list: D001572:Benzofurans; D010666:Phenylpropionates; D011753:Pyrones; C449755:cryphonectric acid; C437445:orthosporin; C001418:4-hydroxyphenyllactic acid; C437444:diaporthin