Quorum-sensing signals and quorum-sensing genes in Burkholderia vietnamiensis.
Acyl-homoserine lactone (acyl-HSL) quorum sensing is common to many Proteobacteria including a clinical isolate of Burkholderia cepacia. The B. cepacia isolate produces low levels of octanoyl-HSL. We have examined an environmental isolate of Burkholderia vietnamiensis. This isolate produced several acyl-HSLs. The most abundant species was decanoyl-HSL. Decanoyl-HSL in B. vietnamiensis cultures reached concentrations in excess of 20 microM. We isolated a B. vietnamiensis DNA fragment containing a gene for the synthesis of decanoyl-HSL (bviI) and an open reading frame that codes for a putative signal receptor (bviR). A B. vietnamiensis bviI mutant did not produce detectable levels of decanoyl-HSL.
Conway
Barbara-Ann
BA
Department of Microbiology, University of Iowa, Iowa City, Iowa 52242, USA.
Greenberg
E P
EP
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000235:genetics* / Q000378:metabolism; D019117:Burkholderia / Q000235:genetics* / Q000378:metabolism; D005798:Genes, Bacterial
C088386:homoserine lactone; D015107:4-Butyrolactone