title: Computer-assisted diagnostics: application to prostate cancer.
abstract: Artificial neural networks (ANNs) have only recently been applied to solve problems in the diagnosis, staging, and prediction of treatment outcome in prostate cancer. A literature search provided information on 10 published journal articles that were selected for review and analysis. In all but one of the studies that compared the ANN output with logistic regression modeling, the ANN performed better. Specific training issues for neural networks are discussed and examples provided. We conclude that the continued development and refinement of computer-assisted diagnostic methodology are warranted to enhance conventional statistical approaches to the classification and pattern recognition found in data sets from men either suspected of having or known to have prostate cancer.
authors.affiliation: Department of Urology, The University of Texas-M.D. Anderson Cancer Center, Houston, Texas 77030-4095, USA. rbabaian@mdanderson.org
authors.forename: R J
authors.initials: RJ
authors.lastname: Babaian
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D003936:Diagnosis, Computer-Assisted; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D016571:Neural Networks, Computer; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D016896:Treatment Outcome
chemical_list: D017430:Prostate-Specific Antigen