CTX-M-1, CTX-M-3, and CTX-M-14 beta-lactamases from Enterobacteriaceae isolated in France.
Six clinical CTX-M-producing isolates of the family Enterobacteriaceae were detected between 1999 and 2000 in different French hospitals. Two strains produced CTX-M-1 and CTX-M-3 and four strains produced CTX-M-14, a mutant Ala-231-->Val of CTX-M-9. A putative transposable element, ISEcp-1, was located 43 bp upstream of all the bla(CTX-M) genes. Two CTX-M-14-encoding plasmids exhibited similar restriction patterns. The CTX-M-1- and CTX-M-3-encoding plasmids were related to the CTX-M-1- and CTX-M-3-encoding plasmids previously reported in 1990 in France and in 1998 in Poland, respectively.
Dutour
C
C
Laboratoire de Bactériologie, Faculté de Médecine, 63001 Clermont-Ferrand Cedex, France.
Bonnet
R
R
Marchandin
H
H
Boyer
M
M
Chanal
C
C
Sirot
D
D
Sirot
J
J
D004251:DNA Transposable Elements / Q000235:genetics; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics; D029968:Escherichia coli Proteins; D005602:France; D006801:Humans; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D004251:DNA Transposable Elements; D029968:Escherichia coli Proteins; C412613:CTX-M-9 protein, E coli; C417271:beta-lactamase CTX-M-3; C055184:beta-lactamase TEM-3; D001618:beta-Lactamases