Aspiration biopsy of nodular sarcoidosis of the muscle.
The nodular form of muscular sarcoidosis is rare and the condition is often confused with a soft tissue neoplasm. We present a case of nodular muscular sarcoidosis of the right calf in a 52-yr-old woman which was diagnosed by thin-needle aspiration biopsy (TNAB). In this patient, a calf mass was the initial manifestation of sarcoidosis. Contrast-enhanced computed tomographic scans of the calf showed a mass with peripheral ring-like enhancement. T2-weighted magnetic resonance images demonstrated a mass with central hypointensity and marked peripheral hyperintensity. TNAB revealed noncaseating epithelioid cell granulomas in association with multinucleated giant cells. Combined with the radiologic findings, TNAB is considered a useful modality for the diagnosis of nodular muscular sarcoidosis.
Yamamoto
Tetsuji
T
Department of Orthopaedic Surgery, Kobe University School of Medicine, Kobe, Japan. yamatetu@med.kobe-u.ac.jp
Nagira
Keiko
K
Akisue
Toshihiro
T
Marui
Takashi
T
Hitora
Toshiaki
T
Nakatani
Tetsuya
T
Kurosaka
Masahiro
M
Tsukamoto
Ryuko
R
D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D009135:Muscular Diseases / Q000473:pathology*; D012507:Sarcoidosis / Q000473:pathology*; D014057:Tomography, X-Ray Computed