[Impaired cardiovascular system in patients with HIV-infection and manifested cytomegalovirus infection].
OBJECTIVE
To assess the condition of the cardiovascular system in HIV-infected patients with manifest cytomegalovirus (CMV) infection.


METHODS
The condition of the cardiovascular system was studied in 21 HIV-infected patients with manifest CMV infection using the following diagnostic methods: clinical, electrocardiographic, echocardiographic, histological ones, measurement of activity of cardiospecific enzymes.


RESULTS
CMV infection the affects functional and morphometric parameters of the cardiac muscle evident as cavity dilatation, increased myocardial mass, low myocardial contractility. CMV is involved in development of dilated cardiomyopathy. Specific therapy with cimeven had a good effect on morphofunctional characteristics of the myocardium.


CONCLUSIONS
Development of manifest CMV infection and affection of cardiovascular system are related.
Filippov
P G
PG
Shakhil'dian
V I
VI
Iushchuk
N D
ND
D017088:AIDS-Related Opportunistic Infections / Q000209:etiology*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D003586:Cytomegalovirus Infections / Q000209:etiology*; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology