[Procalcitonin rapid test in surgical patients treated in the intensive care unit].
Procalcitonin test (PCT) has been proposed to check severity of generalized infections or sepsis. The authors measured the PCT values with PCT-Q quick test (BRAHMS DIAGNOSTICA GmbH, Berlin) at 14 surgical patients treated in their intensive care unit (7 sepsis, 4 peritonitis, 2 localized pancreatic abscess, 1 postoperative fever). At 3 septic patients (2 pancreatitis, 1 intestinal necrosis) they measured the PCT levels repeatedly during treatment. In 2 patients with localized pancreatic abscess and in 1 patient with postoperative fever without evidence of infection the PCT levels were low (< 0.5 ng/ml). At 4 patients with peritonitis following gastric or colon perforation the PCT levels were highly elevated (> 10 ng/ml). At 7 patients with severe sepsis the PCT values were high (> 2 ng/ml), except for 1 patient with intestinal necrosis. At this patient the PCT levels were repeatedly low. In 2 septic patients with pancreatitis elevated PCT levels indicated the need for surgery. In most patients PCT was a good indicator of generalized infections. PCT levels measured repeatedly in sepsis were lower than in patients with peritonitis.
Pinkola
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K
Semmelweis Egyetem Altalános Orvostudományi Kar, I. sz. Sebészeti Klinika, 1082 Budapest, Ullói út 78.
Darvas
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K
D000038:Abscess / Q000097:blood; D000328:Adult; D000368:Aged; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D003422:Critical Care / Q000379:methods*; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D007410:Intestinal Diseases / Q000097:blood; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010195:Pancreatitis / Q000097:blood; D019283:Pancreatitis, Acute Necrotizing / Q000097:blood; D010538:Peritonitis / Q000097:blood; D011237:Predictive Value of Tests; D011498:Protein Precursors / Q000097:blood*; D018805:Sepsis / Q000097:blood
C000606589:CALCA protein, human; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide