title: Ruptured epidermoid cyst and haematoma of spleen: a diagnostic clue of high levels of serum carcinoembryonic antigen, carbohydrate antigen 19-9 and Sialyl Lewis x.
abstract: Splenic epidermoid cyst is a rare disease and that with haematoma is even more rare. The case of epidermoid cyst of the spleen is described, in a 36-year-old Japanese female, manifesting as left hypochondralgia and rupture of the cyst. Clinical features were splenic lesion 14 cm in diameter and consisting of round-hypovascular and crescent-hypervascular sublesions. Extravasation of cystic fluid was detected in abdominal cavity Preoperative diagnosis was difficult due to such uncommon features, however high levels of serum tumour markers (carcinoembryonic antigen, carbohydrate antigen 19-9, Sialyl Lewis x) strongly suggested epidermoid cyst. Laparotomic splenectomy and cholecystectomy were performed for splenic lesion and gallstones, and serum tumour markers decreased following surgery. Pathological diagnosis of the round-hypovascular lesion was epidermoid cyst and crescent-hypervascular lesion was haemorrhage (haematoma).
authors.affiliation: Department of Gastroenterology, Tachikawa General Hospital, Nagaoka, Niigata, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsubayashi
authors.forename: K
authors.initials: K
authors.lastname: Kuraoka
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Yokota
authors.forename: Y
authors.initials: Y
authors.lastname: Iiri
authors.forename: K
authors.initials: K
authors.lastname: Shichijo
authors.forename: T
authors.initials: T
authors.lastname: Tada
authors.forename: K
authors.initials: K
authors.lastname: Satoh
authors.forename: H
authors.initials: H
authors.lastname: Kijima
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D018395:CA-19-9 Antigen / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002763:Cholecystectomy / Q000379:methods; D002769:Cholelithiasis / Q000150:complications* / Q000601:surgery; D004814:Epidermal Cyst / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006406:Hematoma / Q000150:complications* / Q000601:surgery; D006801:Humans; D010535:Laparoscopy; D009844:Oligosaccharides / Q000032:analysis; D012422:Rupture, Spontaneous; D000080506:Sialyl Lewis X Antigen; D013156:Splenectomy / Q000379:methods; D013158:Splenic Diseases / Q000150:complications* / Q000175:diagnosis / Q000601:surgery
chemical_list: D015415:Biomarkers; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen; D009844:Oligosaccharides; D000080506:Sialyl Lewis X Antigen