title: Maternal and perinatal outcomes in women with gestational diabetes mellitus as compared to nondiabetic controls.
abstract: OBJECTIVE
  To determine maternal and fetal outcomes in pregnancies complicated by gestational diabetes mellitus as compared to nondiabetic pregnancies matched on the basis of age and parity and to study the association between different treatment regimens and fetal outcomes.
  
  
  METHODS
  The records of 128 consecutive pregnancies complicated with gestational diabetes mellitus and 138 nondiabetic controls matched on the basis of age and parity were studied. Patients with gestational diabetes mellitus were treated either with diet only or diet in combination with insulin. Data were collected from medical records of the patients and birth records of the newborns.
  
  
  RESULTS
  Despite treatment, the gestational diabetes mellitus group had a significantly higher frequency of cesarean section, preterm delivery and admission to a neonatal unit (P < .05). Preterm delivery and admission to a neonatal unit were significantly higher in the gestational diabetics treated with diet plus insulin as compared to the diet-only group (P < .05).
  
  
  CONCLUSIONS
  Pregnancies complicated by gestational diabetes mellitus are associated with a higher frequency of adverse maternal and fetal outcomes, and adverse outcomes seems to be more frequent in patients treated with diet plus insulin.
authors.affiliation: Department of Obstetrics and Gynecology, Ege University Faculty of Medicine, Bornova, Izmir 35100, Turkey. sendag@med.ege.edu.tr
authors.forename: F
authors.initials: F
authors.lastname: Sendag
authors.forename: M C
authors.initials: MC
authors.lastname: Terek
authors.forename: I M
authors.initials: IM
authors.lastname: Itil
authors.forename: K
authors.initials: K
authors.lastname: Oztekin
authors.forename: O
authors.initials: O
authors.lastname: Bilgin
mesh_terms: D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D002585:Cesarean Section; D016640:Diabetes, Gestational / Q000150:complications*; D004032:Diet; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007231:Infant, Newborn; D007328:Insulin / Q000627:therapeutic use; D007363:Intensive Care Units, Neonatal; D007752:Obstetric Labor, Premature / Q000209:etiology; D010298:Parity; D011247:Pregnancy; D011256:Pregnancy Outcome; D012307:Risk Factors
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin