[Light inhibits tyrosine kinase in rod outer segments in vitro].
It was shown that short-term (10 min) light exposure of dark-adapted retinal rod outer segments (ROS) leads to a threefold inhibition of the tyrosine kinase activity. Tyrosine kinase activity in the ROS from bleached retinas is by 30% lower than in the dark-adapted ROS. Prolonged illumination (60 min) of the dark-adapted ROS restores the tyrosine kinase activity to the level of ROS from the bleached retinas.
Sholukh
A M
AM
Institute of Photobiology, National Academy of Sciences of Belarus, ul. Akademicheskaya 27, Minsk, 220072 Belarus. sholukh@bas07.bas-net.by
Artamonov
I D
ID
Baranova
L A
LA
Lipkin
V M
VM
Volotovskiĭ
I D
ID
D000818:Animals; D002417:Cattle; D003623:Dark Adaptation; D066298:In Vitro Techniques; D008027:Light; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D012374:Rod Cell Outer Segment / Q000201:enzymology / Q000528:radiation effects*
D011505:Protein-Tyrosine Kinases