title: Ischemic stroke therapy.
abstract: Stroke is the most common life-threatening neurologic disease and the leading cause of serious long-term disability. The advent of new treatment options for selected patients suffering ischemic stroke (such as systemic administration of tissue plasminogen activator or catheter-guided intra-arterial thrombolysis), the structural reorganization of patient care facilities into stroke units, and interdisciplinary cerebrovascular centers have broadened the scope of possible therapeutic interventions in the acute and post-acute phase after cerebral ischemia. This review summarizes currently available and recommended treatment modalities for acute ischemic stroke from an interdisciplinary perspective, including medical, neurointerventional, and neurosurgical therapies.
authors.affiliation: The Neurological Institute, Columbia University College of Physicians and Surgeons, 710 West 168th Street, New York, New York 10032, USA.
authors.forename: C
authors.initials: C
authors.lastname: Stapf
authors.forename: J P
authors.initials: JP
authors.lastname: Mohr
mesh_terms: D000208:Acute Disease; D002544:Cerebral Infarction / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D004185:Disability Evaluation; D006757:Hospital Units; D006801:Humans; D011379:Prognosis; D015996:Survival Rate; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage
chemical_list: D010959:Tissue Plasminogen Activator