Structural remodeling of the synapse in response to physiological activity.
Synaptic actin has now been shown to change shape in response to stimulation. The cytoskeleton may therefore be pivotal in integrating molecular and morphological changes associated with synaptic plasticity and coordinating such changes across pre- and postsynaptic compartments.
Huntley
George W
GW
Fishberg Research Center for Neurobiology, The Mount Sinai School of Medicine, 1425 Madison Avenue, New York, NY 10029, USA. george.huntley@mssm.edu
Benson
Deanna L
DL
Colman
David R
DR
D000199:Actins / Q000502:physiology*; D000818:Animals; D003599:Cytoskeleton / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology; D013569:Synapses / Q000502:physiology*
D000199:Actins