title: Single breath-hold multi-slab and cine cardiac-synchronized gadolinium-enhanced three-dimensional angiography.
abstract: The rest period of the coronary arteries has been shown to be on the order of 120-160 msec. Restriction of the acquisition window in breath-hold cardiac-synchronized gadolinium-enhanced imaging to this duration limits the amount of sampled k-space data and hence the information when compared with conventional gadolinium-enhanced imaging. Two techniques for gadolinium-enhanced cardiac-synchronized angiography were implemented that acquire additional data during the unused portions of the cardiac cycle. Data acquisition is synchronized with the heart cycle and is restricted to a short period of each heart cycle. In a single breath-hold, a multi-slab acquisition (n = 5) allowed ECG-synchronized imaging of the entire heart or a CINE acquisition (n = 5) provided multiple stacks of images at different phases in the cardiac cycle over a smaller area. Preliminary results acquired in healthy volunteers and patients with aortic disease indicate that additional information can be acquired without an increase in breath-hold duration or a reduction in image quality.
authors.affiliation: Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. james.goldfarb@umdnj.edu
authors.forename: J W
authors.initials: JW
authors.lastname: Goldfarb
authors.forename: A E
authors.initials: AE
authors.lastname: Holland
authors.forename: R R
authors.initials: RR
authors.lastname: Edelman
mesh_terms: D000328:Adult; D000368:Aged; D002932:Cineangiography / Q000379:methods*; D003287:Contrast Media; D017023:Coronary Angiography / Q000379:methods*; D019786:Gadolinium DTPA; D006321:Heart / Q000502:physiology; D006801:Humans; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008875:Middle Aged; D012119:Respiration; D013997:Time Factors
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA