Occupational and environmental risks of spontaneous abortions around a smelter.
BACKGROUND
This study represents part of a follow-up study on reproductive outcome around a smelter in Sweden.


METHODS
Employees at the smelter, a random sample including neighbors of the smelter and referents were analyzed by a register study, covering 1982-1990, a questionnaire study performed in 1992 and a case-referent study with cases of spontaneous abortions and live borns as referents. Risk factors were studied by logistic regression. A validity-study between register and questionnaire data on spontaneous abortions and legal abortions was completed.


RESULTS
The studies showed no risk increase for the exposed groups of smelter workers and neighbors compared to the reference group, 10, 11, and 12%, respectively. A validation of the data on abortions between register and questionnaire data showed good agreement.


CONCLUSIONS
We found no increase of spontaneous abortion associated to smelter work or to living close to the smelter which could be a result of radically reduced emissions.
Wulff
Marianne
M
Department of Epidemiology, Public Health and Clinical Medicine, Umeå University, Sweden. marianne.wulff@epiph.umu.se
Högberg
Ulf
U
Stenlund
Hans
H
D000022:Abortion, Spontaneous / Q000453:epidemiology / Q000209:etiology*; D000328:Adult; D003430:Cross-Sectional Studies; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008019:Life Style; D016015:Logistic Models; D008669:Metallurgy; D016273:Occupational Exposure / Q000009:adverse effects*; D011247:Pregnancy; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology; D014798:Vital Statistics