title: Stroke related to carotid artery dissection in a young patient with Takayasu arteritis, systemic lupus erythematosus and antiphospholipid antibody syndrome.
abstract: Autoimmune diseases are rarely the cause of stroke even in the young age group in association with cervical artery dissection and collagen vascular diseases. Takayasu arteritis is a chronic, idiopathic, inflammatory disease that primarily affects large vessels, such as the aorta and its main branches. Takayasu arteritis rarely coexists with systemic lupus erythematosus, and only few cases have been reported in association with the presence of antiphospholipid antibodies. We describe a young patient with right internal carotid artery dissection and subsequent stroke who presented with all three syndromes. Although this patient met the diagnostic criteria for each syndrome, systemic lupus erythematosus, Takayasu arteritis and the antiphospholipid antibody syndrome, it remains unlikely that the three disorders are not related. We suggest a single disimmune disorder may have led to carotid artery dissection.
authors.affiliation: Stroke Unit, Department of Neuroscience, Unit of Internal Medicine and Oncological Sciences, University of Perugia, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Caso
authors.forename: M
authors.initials: M
authors.lastname: Paciaroni
authors.forename: L
authors.initials: L
authors.lastname: Parnetti
authors.forename: G
authors.initials: G
authors.lastname: Cardaioli
authors.forename: L
authors.initials: L
authors.lastname: Biscarini
authors.forename: A E
authors.initials: AE
authors.lastname: Acciarini
authors.forename: S
authors.initials: S
authors.lastname: Rubino
authors.forename: V
authors.initials: V
authors.lastname: Gallai
mesh_terms: D000328:Adult; D020215:Carotid Artery, Internal, Dissection / Q000150:complications*; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D020521:Stroke / Q000209:etiology*; D013625:Takayasu Arteritis / Q000150:complications*