Chondrosarcoma of the skull base.
OBJECTIVE
Sarcomas of the skull base are challenging, potentially lethal tumors. Prognosis is considered poor. The present report reviews treatment options and presents a case of treatment with en bloc resection of the temporal bone and adjacent skull base.


METHODS
Single case report and literature review.


RESULTS
Extensive skull base resection for chondrosarcoma can be performed successfully and may be curative.


CONCLUSIONS
There is a role for en bloc resection of large areas of the skull base for treatment of chondrosarcoma. It appears that treatment combining surgery and radiation therapy is most likely to be effective.
Neff
Brian
B
Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, 1721 Pine Street, Philadelphia, PA 19103, U.S.A.
Sataloff
Robert Thayer
RT
Storey
Leslie
L
Hawkshaw
Mary
M
Spiegel
Joseph R
JR
D000328:Adult; D002813:Chondrosarcoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D003399:Craniotomy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011183:Postoperative Complications / Q000209:etiology / Q000601:surgery; D011379:Prognosis; D012086:Reoperation; D019291:Skull Base / Q000473:pathology / Q000601:surgery; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D013701:Temporal Bone / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed