[Clinical study on treatment of incipient diabetic nephropathy by integrated traditional Chinese and Western medicine].
OBJECTIVE
To explore the curative effect of integrated traditional Chinese and western medicine (TCM-WM) on incipient diabetic nephropathy (DN).


METHODS
One hundred patients with incipient DN were randomly divided into two groups, the treatment group (50 cases) was treated with TCM-WM therapy, which was carried out by using Jiangtang Janshenling (JTJSL) capsule, a Chinese preparation for supplementing Qi and nourishing Yin, on the basis of controlling blood glucose with western medicine effectively. The 50 patients in the control group were treated with western medicine alone. The course of treatment was three months. Changes of symptoms, signs, and related laboratory parameters were observed before and after treatment.


RESULTS
The total effective rate in the treatment group was 90% while that in the control group was 58%, the difference between two groups was significant (P < 0.05). The related parameters including 24 hours urinary albumin excretion, blood sugar, microalbuminuria, blood and urine beta 2-microglobulin, blood lipids, and hemorrheology levels were all improved after treatment in the treatment group (P < 0.05 or P < 0.01).


CONCLUSIONS
The curative effect of TCM-WM was better than that of western medicine alone in treating incipient DN.
Bian
F
F
Department of Endocrinology, People's Hospital of Cangzhou, Hebei 061000.
Zhao
P
P
Zhang
Z
Z
D000328:Adult; D000368:Aged; D002214:Capsules; D003928:Diabetic Nephropathies / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008687:Metformin / Q000627:therapeutic use*; D008875:Middle Aged; D019413:Qi; D016710:Yin Deficiency / Q000188:drug therapy
D002214:Capsules; D004365:Drugs, Chinese Herbal; D007004:Hypoglycemic Agents; D008687:Metformin