title: MEN-10700 menarini.
abstract: Menarini is investigating the penem beta-lactam antibiotic, MEN-10700, for the potential control of bacterial infections. MEN-10700 compares favorably with other oral beta-lactams against Haemophilus influenzae strains as well as other respiratory pathogens [341073]. The compound has also showed activity against multiple drug-resistant Gram-negative pathogens [341074]. MEN-10700 has a broad spectrum of activity against Gram-positive and Gram-negative bacteria and demonstrates a potency greater than that of imipenem [174404].
authors.affiliation: Charles University Hospital, Department of Ophthalmology, Kralove, Czech Republic. kvasnicka@lfhk.cuni.cz
authors.forename: N
authors.initials: N
authors.lastname: Jiraskova
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D007769:Lactams; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D007769:Lactams; C106870:Men 10700