title: [Acoustic analysis of nocturnal bronchial obstruction].
abstract: Patients with obstructive pulmonary disease also have respiratory problems in sleep. The continuous acoustic lung sound detection together with a cardiorespiratory polysomnography allows a synchronous registration of bronchial obstruction as well as vigilance and respiratory parameters in sleep.A total of 20 patients (9 male and 11 female) with known obstructive airway disease and evident diurnal bronchial obstruction were investigated. We did a monitoring in all patients with a nocturnal continuous acoustic lung sound detection together with a cardiorespiratory polysomnography. The mean age was 55 +/- 12 years (range 23 to 74). In all patients acoustic nocturnal bronchial obstructions could be registered. The wheezing-time (time portion of wheezing while sleeping) was 32.1 +/- 27.4 % (mean +/- SD). We could not proof reliable a rhythm of bronchial obstructions. Only 3 patients had increased bronchial obstructions between 3 and 5 AM. The sleep structure was disturbed in 16 of 20 patients with reduced deep sleep, REM sleep and prolonged sleep latency. Knowing about nocturnal bronchial obstructions helps to adapt the antiobstructive therapy. One can expect that an improvement of the respiratory situation also improves sleep quality.
authors.affiliation: Klinik für Innere Medizin, SP Pneumologie und Schlafmedizin, Philipps-Universität, Marburg, Germany. koehleru@mailer.uni-marburg.de
authors.forename: U
authors.initials: U
authors.lastname: Koehler
authors.forename: V
authors.initials: V
authors.lastname: Gross
authors.forename: C
authors.initials: C
authors.lastname: Reinke
authors.forename: T
authors.initials: T
authors.lastname: Penzel
authors.forename: C F
authors.initials: CF
authors.lastname: Vogelmeier
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D012135:Respiratory Sounds / Q000502:physiology*; D012680:Sensitivity and Specificity; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000503:physiopathology; D013018:Sound Spectrography