title: Ultrasound-guided skeletal biopsies.
abstract: OBJECTIVE
  Percutaneous biopsy of skeletal lesions is a widely used diagnostic technique that involves fluoroscopic or computerized tomography guidance. The objective of this report is to describe the use of ultrasonography in the guidance of percutaneous biopsy of skeletal lesions.
  
  
  METHODS
  We employed ultrasound to guide percutaneous biopsy in 65 skeletal lesions in 63 patients (30 male and 33 female) whose ages ranged from 1 to 82 years (mean 47.2 years ). The lesions were divided into four groups: group 1 ( n=41) were lytic with a soft tissue mass, group 2 ( n=14) were lytic with a disrupted cortex without a soft tissue mass, group 3 ( n=4) were lytic with an intact cortex and group 4 ( n=6) were sclerotic lesions. Different techniques and materials were used in each group.
  
  
  RESULTS
  Cytologic assessment obtained the diagnosis in 50 cases, (success rate 76.9%), histology in 56 cases (86.1%) and a combination of both in 60 cases (92.3%). There were no complications.
  
  
  CONCLUSIONS
  Ultrasound is a highly accurate and safe method of guidance in percutaneous biopsy of bone lesions, either lytic or sclerotic, because it can identify subtle changes in the cortical and the associated soft tissue component.
authors.affiliation: Department of Radiology, Hospital General Universitario de Alicante, C/ Pintor Baeza, s/n. 03010, Alicante, Spain. sgils@coma.es
authors.forename: S
authors.initials: S
authors.lastname: Gil-Sánchez
authors.forename: S F
authors.initials: SF
authors.lastname: Marco-Doménech
authors.forename: J
authors.initials: J
authors.lastname: Irurzun-López
authors.forename: P
authors.initials: P
authors.lastname: Fernández-García
authors.forename: P
authors.initials: P
authors.lastname: de la Iglesia-Cardeña
authors.forename: S
authors.initials: S
authors.lastname: Ambit-Capdevila
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D018615:Ultrasonography, Doppler, Color