Elements in erythrocytes of population with different thyroid hormone status.
The contents of elements K, Ca, Fe, Cu, Zn, Se, and Rb in erythrocytes of 78 cases with different thyroid hormone status have been measured by proton-induced X-ray emission and neutron activation analysis. According to the status of thyroid hormones T3, T4, TSH, FT3, and FT4 detected by radioimmunoassay, the experiment subjects were divided into four groups (i.e., hyperthyroid, hypothyroid, critical [one of thyroid hormones was abnormal], and normal). Elements contents and hormones levels of four groups were analyzed by one-way analysis of variance and correlation using an SPSS/PC statistical package. The results showed that the Se contents of four groups were not significantly different (p<0.05). Zn content of hypothyroid group was significantly higher than those of hyperthyroid and critical groups. The Zn content of the normal group was higher than that of the hypothyroid group and lower than that of the hyperthyroid and critical groups. In the hyperthyroid group, there were significant correlations between elements contents and thyroid hormones levels (except TSH), but not between elements contents and levels of thyroid hormones. However, in the hypothyroid group, relatively strong correlations have been found between elements contents and thyroid hormones levels, especially between Zn and the T3/T4 ratio, and between Zn and TSH.
Liu
N
N
Institute of High Energy Physics, Chinese Academy of Sciences, Beijing.
Liu
P
P
Xu
Q
Q
Zhu
L
L
Zhao
Z
Z
Wang
Z
Z
Li
Y
Y
Feng
W
W
Zhu
L
L
D000818:Animals; D002118:Calcium / Q000097:blood; D002417:Cattle; D003300:Copper / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism*; D006111:Graves Disease / Q000097:blood; D006801:Humans; D007455:Iodine / Q000097:blood; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D007501:Iron / Q000097:blood; D009502:Neutrons; D010125:Ostreidae; D011188:Potassium / Q000097:blood; D011522:Protons; D011863:Radioimmunoassay; D012413:Rubidium / Q000097:blood; D012643:Selenium / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood*; D014131:Trace Elements / Q000097:blood*; D014965:X-Rays; D015032:Zinc / Q000097:blood
D007457:Iodine Radioisotopes; D011522:Protons; D013963:Thyroid Hormones; D014131:Trace Elements; D003300:Copper; D007455:Iodine; D007501:Iron; D012643:Selenium; D015032:Zinc; D012413:Rubidium; D011188:Potassium; D002118:Calcium