title: High-throughput analytical techniques for reaction optimization.
abstract: This review describes recent developments in approaches to high-throughput reaction optimization, as well as the associated analytical techniques. The studies discussed include the use of UV-visible, IR-thermographic and mass spectrometric methods for application in catalyst development, process optimization and materials science. Other methods of potential use in a high-throughput format are also discussed.
authors.affiliation: Astex Technology, 250 Cambridge Science Park, Milton Road, Cambridge, UK CB4 0WE. m.congreve@astex-technology.com
authors.forename: Miles S
authors.initials: MS
authors.lastname: Congreve
authors.forename: Craig
authors.initials: C
authors.lastname: Jamieson
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods* / Q000458:organization & administration*; D013058:Mass Spectrometry; D004364:Pharmaceutical Preparations / Q000032:analysis / Q000138:chemical synthesis / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D004364:Pharmaceutical Preparations