Transcriptional control: an activating role for arginine methylation.
A rare histone modification, arginine methylation, has been linked to activation of hormone-responsive genes. Interestingly, methylation of a lysine residue in the same histone is present prior to hormone activation, but is excluded from the active loci.
Davie
Judith K
JK
Department of Biochemistry and Molecular Biology, U.T. M.D. Anderson Cancer Center, Houston, Texas 77030, USA.
Dent
Sharon Y R
SY
D000818:Animals; D001120:Arginine / Q000378:metabolism*; D019175:DNA Methylation; D006728:Hormones / Q000502:physiology; D015533:Transcriptional Activation / Q000502:physiology*
D006728:Hormones; D001120:Arginine