title: [Severe metabolic alkalosis following hypokalemia from a paraneoplastic Cushing syndrome].
abstract: Metabolic alkalosis is frequently observed in critically ill patients. Etiologies are numerous but endocrinal causes are rare. We report a case of a patient with severe respiratory insufficiency, metabolic alkalosis and hypokalemia. The evolution was fatal. Further explorations revealed an ectopic Adrenocorticotropine Hormone syndrome. The initial tumor was probably a small cell lung carcinoma.
authors.affiliation: Département d'anesthésie-réanimation, CHU Angers, 4, rue Larrey, 49035 Angers, France. Ladube@chu-angers.fr
authors.forename: L
authors.initials: L
authors.lastname: Dubé
authors.forename: S
authors.initials: S
authors.lastname: Daenen
authors.forename: A
authors.initials: A
authors.lastname: Kouatchet
authors.forename: C
authors.initials: C
authors.lastname: Soltner
authors.forename: P
authors.initials: P
authors.lastname: Alquier
mesh_terms: D000182:ACTH Syndrome, Ectopic / Q000150:complications* / Q000378:metabolism; D000471:Alkalosis / Q000209:etiology* / Q000378:metabolism; D003480:Cushing Syndrome / Q000150:complications* / Q000378:metabolism; D017809:Fatal Outcome; D006801:Humans; D007008:Hypokalemia / Q000150:complications* / Q000209:etiology / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000209:etiology / Q000503:physiopathology