title: Churg-Strauss syndrome occurring 30 years after the onset of ulcerative colitis.
abstract: Churg-Strauss syndrome (CSS) is a rare pulmonary and systemic vasculitis associated with asthma, with peripheral blood and/or tissue eosinophilia. We report the case of a 53-year-old woman who was admitted to the hospital with pneumonia and coma secondary to right hemisphere intracerebral hemorrhage. Although she recovered from the pneumonia, she remained comatose and had sinusitis and persisting blood eosinophilia. A muscle biopsy revealed eosinophilic vasculitis. The diagnosis of CSS was made and the patient recovered after being treated with prednisone and cyclophosphamide. This case reports the very rare appearance of CSS 30 years after the first appearance of ulcerative colitis and 27 years after the onset of asthma.
authors.affiliation: Critical Care Department, Tzanio General Hospital, Tzani and Afentouli 1, GR-18 536, Piraeus, Greece. prekates@ath.forthnet.gr
authors.forename: Athanasios A
authors.initials: AA
authors.lastname: Prekates
authors.forename: Stylianos E
authors.initials: SE
authors.lastname: Orfanos
authors.forename: Christina J
authors.initials: CJ
authors.lastname: Routsi
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Ch Pantelidaki
authors.forename: Charis S
authors.initials: CS
authors.lastname: Roussos
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000150:complications*; D015267:Churg-Strauss Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003093:Colitis, Ulcerative / Q000150:complications*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D018501:Antirheumatic Agents; D005938:Glucocorticoids; D003520:Cyclophosphamide; D011241:Prednisone