title: Polycystic kidney disease as a new risk factor for coronary events.
abstract: BACKGROUND
  The association between coronary and/or other arterial aneurysms and polycystic kidney disease is well known. While myocardial infarction is a possible complication of atheroscletotic coronary aneurysms, it is reasonable to assume that CA in patients with PKD may make them prone for a similar complication.
  
  
  OBJECTIVE
  To evaluate the possible occurrence of CA and MI in first-order relatives of a patient with PKD, CA and MI.
  
  
  METHODS
  We studied 12 family members: 2 parents, 8 sisters and 2 brothers of a young woman who was incidentally diagnosed as having a MI, while her mother was known to have PKD. We used electrocardiogram, thallium-image test, and transthoracic echocardiography to determine MI, ultrasonography of the kidney to determine PKD, and coronary angiography and ventriculography to determine CA and MI, respectively.
  
  
  RESULTS
  PKD was detected in seven family members, while CA and MI were found in five and three of them, respectively.
  
  
  CONCLUSIONS
  In a family with PKD we detected a high prevalence of CA, with MI as a complication of the latter.
authors.affiliation: Department of Medicine A, Hillel Yaffe Medical Center, Hadera, Israel. library@hillel-yaffe.health.gov.il
authors.forename: Rasmi
authors.initials: R
authors.lastname: Magadle
authors.forename: Paltiel
authors.initials: P
authors.lastname: Weiner
authors.forename: Marinella
authors.initials: M
authors.lastname: Rabner
authors.forename: Miri
authors.initials: M
authors.lastname: Mizrahi-Reuveni
authors.forename: Avi
authors.initials: A
authors.lastname: Davidovich
mesh_terms: D000328:Adult; D000368:Aged; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology* / Q000235:genetics; D017023:Coronary Angiography; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics; D007690:Polycystic Kidney Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics; D015635:Radionuclide Ventriculography; D012307:Risk Factors; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes