title: Clinical evaluation of Prime & Bond 2.1 for treating cervical dentin hypersensitivity.
abstract: OBJECTIVE
  To evaluate the effectiveness of a "one-bottle" dentin adhesive for reducing or eliminating hypersensitivity in exposed cervical dentin.
  
  
  METHODS
  Eight patients with hypersensitive teeth were enrolled in this clinical trial. The hypersensitive teeth included a total of 22 premolars and anterior teeth with exposed cervical dentin that was sensitive to cold or other stimuli. A single layer of Prime & Bond 2.1, an acetone-based "one-bottle" adhesive, was applied to the cervical dentin and was light-cured. Sensitivity to compressed air and cold stimuli was determined immediately before and after treatment, and at periods ranging to 24 wks after treatment. Patient responses to the stimuli were timed, and were also evaluated by the use of a visual analogue scale.
  
  
  RESULTS
  Application of a single coat of Prime & Bond 2.1 significantly reduced cervical dentin hypersensitivity to both compressed air and cold stimuli immediately after treatment. The reduction in hypersensitivity remained significant at 24 wks after treatment.
authors.affiliation: Dept. of Operative Dentistry, University of North Carolina, Chapel Hill 27599-7450, USA. Ed_Swift@dentistry.unc.edu
authors.forename: E J
authors.initials: EJ
authors.lastname: Swift
authors.forename: K N
authors.initials: KN
authors.lastname: May
authors.forename: S
authors.initials: S
authors.lastname: Mitchell
mesh_terms: D000096:Acetone / Q000627:therapeutic use*; D000328:Adult; D000388:Air; D000704:Analysis of Variance; D001641:Bicuspid / Q000473:pathology; D003080:Cold Temperature; D016001:Confidence Intervals; D003481:Cuspid / Q000473:pathology; D003807:Dentin Sensitivity / Q000517:prevention & control / Q000628:therapy*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000473:pathology; D016018:Least-Squares Analysis; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D017060:Patient Satisfaction; D011109:Polymethacrylic Acids / Q000627:therapeutic use*; D013997:Time Factors; D019237:Tooth Cervix / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D017220:Dentin-Bonding Agents; D011109:Polymethacrylic Acids; C444444:prime and bond 2.1; D000096:Acetone