title: [Benign intracranial hypertension resulting from corticosteroid withdrawal: case report].
abstract: We report a case of benign intracranial hypertension (BIH) resulting from corticosteroid withdrawal. A 36-year-old woman was admitted to hospital because of an intractable headache. A neurological examination on admission showed no abnormalities other than a headache and nausea. CT, MRI, and angiogram examinations showed no abnormalities. Hematological and laboratory data were also normal. Continuous monitoring of her cerebrospinal fluid (CSF) pressure showed a value of over 25 mmHg during sleep, but papilledema was not observed. A diagnosis of BIH was made, with corticosteroid withdrawal considered to be the most probable cause. The patient was given isosorbide solution for 3 months. However, her clinical condition continued to deteriorate; she eventually began to develop visual loss, photopsia, and memory disturbances. She underwent lumboperitoneal shunt surgery, which immediately eliminated the headache, photopsia, and memory disturbances. She regained her vision over a five-month period. BIH should be considered as a differential diagnosis when an intractable headache develops after corticosteroid withdrawal, especially in young women.
authors.affiliation: Department of Neurosurgery, Haibara General Hospital, 2887-1 Hosoe, Haibara-cho, Haibara-gun, Shizuoka 421-0493, Japan.
authors.forename: Kuniyasu
authors.initials: K
authors.lastname: Saigusa
authors.forename: Hidenori
authors.initials: H
authors.lastname: Takei
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Shishido
authors.forename: Jun
authors.initials: J
authors.lastname: Ohki
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Naoe
authors.forename: Kikuo
authors.initials: K
authors.lastname: Ohno
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005260:Female; D020773:Headache Disorders / Q000209:etiology; D006801:Humans; D011239:Prednisolone / Q000009:adverse effects*; D011559:Pseudotumor Cerebri / Q000139:chemically induced*; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone