Indications for antireflux surgery in Barrett's.
One of the most common complications of gastroesophageal reflux disease is Barrett's esophagus. Medical therapy for this condition is not very effective and does not seem to be able to control the occurence and progression of the disease. In contrast, there is some evidence that effective antireflux surgery does have a slowing effect on the occurence and the progression of Barrett's esophagus. There is also some evidence that the progression of Barrett's to high-grade dysplasia and carcinoma is less after antireflux surgery than during medical therapy. Antireflux surgery should be considered in patients with Barrett's who have a large hiatal hernia, dysplasia, a weak lower esophageal sphincter pressure, failed medical therapy, noncompliance to medications, and young age.
Klaus
A
A
Department of Surgery, University Hospital Innsbruck, Innsbruck, Austria.
Hinder
R A
RA
D001471:Barrett Esophagus / Q000601:surgery*; D018450:Disease Progression; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006551:Hernia, Hiatal / Q000150:complications; D006801:Humans