title: Hemodynamic performance of stentless porcine bioprosthesis and mechanical bileaflet prosthesis using dobutamine stress echocardiography.
abstract: Currently available aortic valve prostheses have satisfactory hemodynamic performance during rest, but with exercise they possess different responses. The objective was to compare the hemodynamic response of the stentless porcine bioprosthesis (SP) and the mechanical bileaflet prosthesis (MB) at rest and during peak exercise using dobutamine stress echocardiography (DSE). DSE was used to evaluate the effective orifice area index (EOAI), peak and mean pressure gradients at rest and during maximum stress in 15 patients with SP (group T, mean age, 30.9 year) and another 15 patients with MB (group M, mean age, 28.6 year). The increment in pressure gradient (mean/peak) was significantly less in patients with SP than those with MB (P <.01). The EOAI did not change with exercise. At rest, both valve substitutes have satisfactory hemodynamics, but during exercise the stentless porcine bioprosthesis has better hemodynamics because it is less obstructive that justifies its use in young population.
authors.affiliation: National Heart Institute, Cardiac Surgery and Cardiology, Imbaba, Cairo, Egypt.
authors.forename: S
authors.initials: S
authors.lastname: Morsy
authors.forename: M
authors.initials: M
authors.lastname: Zahran
authors.forename: M
authors.initials: M
authors.lastname: Usama
authors.forename: K
authors.initials: K
authors.lastname: Elkhashab
authors.forename: I
authors.initials: I
authors.lastname: Abdel-Aziz
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000502:physiology*; D001705:Bioprosthesis; D002302:Cardiac Output / Q000502:physiology*; D002316:Cardiotonic Agents; D004280:Dobutamine; D015150:Echocardiography, Doppler; D025401:Echocardiography, Stress; D005080:Exercise Test; D005260:Female; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011474:Prosthesis Design; D013318:Stroke Volume
chemical_list: D002316:Cardiotonic Agents; D004280:Dobutamine