Regioselective oxidation of phenols to o-quinones with o-iodoxybenzoic acid (IBX).
[reaction: see text] An efficient regioselective method for oxidation of phenols to o-quinones is reported. When this procedure is combined with a subsequent reduction, it proves to be useful for the construction of a variety of catechols.
Magdziak
Derek
D
Department of Chemistry and Biochemistry, University of California at Santa Barbara, Santa Barbara, California 93106, USA.
Rodriguez
Andy A
AA
Van De Water
Ryan W
RW
Pettus
Thomas R R
TR
D002396:Catechols / Q000138:chemical synthesis; D007462:Iodobenzenes; D007463:Iodobenzoates / Q000737:chemistry; D010084:Oxidation-Reduction; D010636:Phenols / Q000737:chemistry; D011809:Quinones / Q000138:chemical synthesis*
D002396:Catechols; D007462:Iodobenzenes; D007463:Iodobenzoates; D010636:Phenols; D011809:Quinones; C476101:o-iodoxybenzoic acid