title: Atresias of the gastrointestinal tract in an inbred, previously unstudied population.
abstract: Retrospective analysis of the records of newborns with gastrointestinal (GI) atresias in a 16-year period revealed that more than 25% of patients had genetically-influenced atresias. Among these, an appreciable increase was observed in atresias confined to the antral region and in a syndrome of hereditary multiple GI atresias. In the absence of environmental and teratogenic factors, this increase could be due to the traditional social practice of endogamy in this population. However, this clinical finding remains to be supported by relevant prospective genetic studies.
authors.affiliation: Department of Pediatric Surgery, Faculty of Medicine, Al-Arab Medical University, Benghazi, Libya.
authors.forename: D B
authors.initials: DB
authors.lastname: Gahukamble
authors.forename: A R M
authors.initials: AR
authors.lastname: Adnan
authors.forename: Musa
authors.initials: M
authors.lastname: Al-Gadi
mesh_terms: D003241:Consanguinity; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000453:epidemiology / Q000235:genetics*; D008002:Libya / Q000453:epidemiology; D008297:Male; D012189:Retrospective Studies