title: Hypertrophic pulmonary osteoarthropathy without clubbing of the digits.
abstract: Hypertrophic osteoarthropathy (HOA) typically occurs concurrently with clubbing of the digits, with isolated HOA being reported only rarely. We report two patients with intra-thoracic malignancy in whom HOA, demonstrated on bone scintigraphy, developed in the absence of clubbing. We also report the novel observation of involvement of the metatarsal and metacarpal bones by HOA.
authors.affiliation: Department of Oncology, Concord Hospital, Sydney, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Clarke
authors.forename: L
authors.initials: L
authors.lastname: Barnsley
authors.forename: M
authors.initials: M
authors.lastname: Peters
authors.forename: L
authors.initials: L
authors.lastname: Morgan
authors.forename: H
authors.initials: H
authors.lastname: Van der Wall
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008663:Metacarpus / Q000000981:diagnostic imaging / Q000473:pathology; D008682:Metatarsal Bones / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000000981:diagnostic imaging*; D010522:Periostitis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging