Influence of sodium bis(oxalato)oxovanadate(IV) on phospholipids in liver Golgi fractions from control and streptozotocin-diabetic rats.
(1) Both vanadyl oxalate and streptozotocin (STZ) caused in comparison with untreated control statistically significant increase (P<0.001 and P<0.02) of PLs (micromoles of P(i) per mg of protein) in rat liver Golgi-rich membrane fraction. (2) The diabetic, vanadium treated rats (D+V) showed lower than control-treated (C+V) content of PLs in these fractions. (3) Three experimental groups of rats: control-treated (P<0.01), diabetic treated with vanadium (P<0.05) and untreated diabetic (P<0.02), had a higher percentage of PI (phosphatidylinositol) in comparison with untreated-control animals.
Kordowiak
A M
AM
Department of Animal Biochemistry, Institute of Molecular Biology, Jagiellonian University, al. Mickiewicza 3, 31-120, Cracow, Poland.
Dudek
B
B
Gryboś
R
R
D000818:Animals; D015415:Biomarkers; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D005260:Female; D005700:Galactosyltransferases / Q000378:metabolism; D006056:Golgi Apparatus / Q000187:drug effects / Q000378:metabolism*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008566:Membranes / Q000187:drug effects / Q000378:metabolism; D010070:Oxalates / Q000494:pharmacology*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014638:Vanadates / Q000494:pharmacology*
D015415:Biomarkers; D010070:Oxalates; D010743:Phospholipids; C106817:bis(oxalato)oxovanadate(IV); D014638:Vanadates; D005700:Galactosyltransferases