title: Does conservative surgical approach improve early and late outcome in patients with acute type A aortic dissection?
abstract: OBJECTIVE
  Acute type A aortic dissection (AAAD) represents an emergency in cardiac surgery that requires immediate treatment to prevent death due to its fatal complications. The surgical approach is dependent on the involvement of AAAD.
  
  
  METHODS
  Sixty-one patients were operated for AAAD at our clinic. 48 (78.7%) were male and 13 (21.3%) were female with a mean age of 51+/-12.3 yr (range, 21-80 yr). Only the ascending aorta was replaced in 33 (54.1%) patients (Group I) and aortic arch replacement was included in 28 (45.9%) patients (Group II). The aortic valve was preserved in 43 (70.5%) patients (Group A) and replaced in 18 (29.5%) patients (Group B).
  
  
  RESULTS
  Early mortality rate was 23% (14/61). Multivariate analysis revealed that previous cardiac operations (P=0.048), renal complications (P=0.024), pump time (P=0.024), and cardiac complications (P=0.017) were significantly factors increasing early mortality. Late mortality rate was 8.5% (4/47) and multivariate analysis revealed that pulmonary complication (P=0.015) was the only statistically significant independent risk factor. Arch replacement or aortic valve replacement was not a predictor for early or late mortality. Cumulative survival was 73.8+/-5.63% at 1 yr and 68.3+/-6.46% at 7.5 yr. Cumulative survival was not different between groups (P>0.05).
  
  
  CONCLUSIONS
  Both radical and conservative surgical approaches in AAAD do not differ in mean of early or late results. Surgery before development of hemodynamic instability and prevention of other system complications improves the outcome of surgical treatment in AAAD.
authors.affiliation: Department of Cardiovascular Surgery, Koşuyolu Heart and Research Hospital, Istanbul, Turkey. imkkirali@yahoo.com
authors.forename: Kaan
authors.initials: K
authors.lastname: Kirali
authors.forename: Denyan
authors.initials: D
authors.lastname: Mansuroğlu
authors.forename: Murat B
authors.initials: MB
authors.lastname: Rabuş
authors.forename: Vedat
authors.initials: V
authors.lastname: Erentuğ
authors.forename: Altuğ
authors.initials: A
authors.lastname: Tuncer
authors.forename: Esat
authors.initials: E
authors.lastname: Akinci
authors.forename: Gökhan
authors.initials: G
authors.lastname: Ipek
authors.forename: Omer
authors.initials: O
authors.lastname: Işik
authors.forename: Cevat
authors.initials: C
authors.lastname: Yakut
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000150:complications* / Q000401:mortality / Q000601:surgery*; D001014:Aortic Aneurysm / Q000150:complications* / Q000401:mortality / Q000601:surgery*; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000601:surgery; D006348:Cardiac Surgical Procedures; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D011237:Predictive Value of Tests; D012086:Reoperation; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography