title: Drosophila windpipe codes for a leucine-rich repeat protein expressed in the developing trachea.
abstract: The embryonic tracheal system of Drosophila provides an important model for understanding the process of epithelial branching morphogenesis. Here we report the sequence and expression analysis of a novel tracheal gene, named windpipe (wdp). wdp is identical to the predicted gene CG3413 and encodes a transmembrane, leucine-rich repeat family member. wdp transcripts appear abruptly at stage 15 and are restricted to primary tracheal branches that give rise to secondary branches.
authors.affiliation: Department of Biological Sciences, University of Nevada Las Vegas, 4505 Maryland Parkway, Las Vegas, NV 89154-4004, USA. jhuff@ccmail.nevada.edu
authors.forename: Janice L
authors.initials: JL
authors.lastname: Huff
authors.forename: Karl L
authors.initials: KL
authors.lastname: Kingsley
authors.forename: Jennell M
authors.initials: JM
authors.lastname: Miller
authors.forename: Deborah K
authors.initials: DK
authors.lastname: Hoshizaki
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D004625:Embryo, Nonmammalian; D018507:Gene Expression Regulation, Developmental; D007930:Leucine; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D020449:Repetitive Sequences, Amino Acid; D014132:Trachea / Q000196:embryology* / Q000378:metabolism
chemical_list: D029721:Drosophila Proteins; D008565:Membrane Proteins; C456267:wdp protein, Drosophila; D007930:Leucine