title: Hemodiafiltration for vancomycin overdose in a patient with end-stage renal failure.
abstract: A 17-year-old anuric female patient with end-stage renal failure received a massive overdose of vancomycin and was treated with high-flux hemodiafiltration, as described in this report. The hemodiafiltration procedure with a polysulfone membrane was performed 3 times. The vancomycin concentration was decreased from 101 mg/l to 16.59 mg/l at the end of the procedure. No adverse effects were noted from either vancomycin or hemodiafiltration. Hemodiafiltration with a high-flux polysulfone membrane is a novel and safe treatment modality for vancomycin overdose in pediatric patients.
authors.affiliation: Department of Pediatric Nephrology, Ege University Medical School, Bornova, full blockzmir, Turkey. Iakil@veezy.com
authors.forename: I O
authors.initials: IO
authors.lastname: Akil
authors.forename: S
authors.initials: S
authors.lastname: Mir
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000097:blood; D001672:Biocompatible Materials; D062787:Drug Overdose / Q000150:complications / Q000628:therapy; D005260:Female; D017583:Hemodiafiltration / Q000295:instrumentation; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008508:Medication Errors; D008567:Membranes, Artificial; D010538:Peritonitis / Q000188:drug therapy; D011108:Polymers; D013450:Sulfones; D014640:Vancomycin / Q000009:adverse effects* / Q000097:blood
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011108:Polymers; D013450:Sulfones; C017662:polysulfone P 1700; D014640:Vancomycin