Diuretic activity of Fabiana patagonica in rats.
A pharmacological evaluation of the diuretic activity of Fabiana patagonica Speg. (Solanaceae) was carried out in isotonic saline loaded rats. The data reported in the present work indicate that the acetone extract and infusion of the aerial part of Fabiana patagonica showed a moderate diuretic activity. This activity could be due, in part, to the presence of oleanolic acid isolated as the major metabolite of F. patagonica.
Alvarez
M E
ME
Departamento de Química Orgánica, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, San Luis, Argentina.
María
A O M
AO
Saad
J R
JR
D000818:Animals; D004232:Diuretics / Q000494:pharmacology*; D005260:Female; D005665:Furosemide / Q000494:pharmacology; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D018520:Plant Shoots / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D019657:Solanaceae; D013997:Time Factors; D014554:Urination / Q000187:drug effects*
D004232:Diuretics; D010936:Plant Extracts; D005665:Furosemide