Papillon-Lefevre syndrome: a case report of four affected siblings.
Four siblings, products of a consanguineous marriage, had palmoplantar keratoderma and loss of teeth. In addition, 3 of the siblings had psoriasiform plaques on their elbows and/or knees and 1 had intracranial calcifications. To our knowledge, this is the second largest reported number of affected members in a family with Papillon-Lefevre syndrome, a rare genodermatosis.
Angel
Tiffany A
TA
Department of Dermatology, Baylor College of Medicine, Houston, TX 77030, USA.
Hsu
Sylvia
S
Kornbleuth
Steven I
SI
Kornbleuth
Joseph
J
Kramer
E Michael
EM
D000328:Adult; D003241:Consanguinity; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010214:Papillon-Lefevre Disease / Q000473:pathology; D011565:Psoriasis / Q000175:diagnosis