Experimental gastric carcinogenesis related to Helicobacter pylori.
In this paper, we present our research on the lipid A of Helicobacter pylori, an experimental study using the Mongolian gerbil model and experimental carcinogenesis using the mouse model to evaluate roles of host factors and bacterial factors which are related to the pathogenicity of Helicobacter pylori including gastric carcinogenesis. Future study on bacterial factors and host factors may give more insight into the role of Helicobacter pylori in gastric carcinogenesis.
Shimoyama
T
T
Department of Gastroenterology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan.
Fukuda
Y
Y
Sakagami
T
T
Yamamoto
N
N
Kashihara
W
W
Okui
M
M
Tanida
N
N
Tamura
K
K
D000818:Animals; D005756:Gastritis / Q000382:microbiology; D005849:Gerbillinae; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori / Q000145:classification; D008050:Lipid A / Q000737:chemistry; D051379:Mice; D008810:Mice, Inbred C57BL; D023421:Models, Animal; D013274:Stomach Neoplasms / Q000382:microbiology*
D008050:Lipid A