Population-based strategies for outreach screening of urogenital Chlamydia trachomatis infections: a randomized, controlled trial.
The effect of 2 population-based outreach screening strategies that used in-home sampling was compared with usual care practices for Chlamydia trachomatis infection. All 30,439 persons 21-23 years old in Aarhus County, Denmark, were divided randomly into 3 groups: group 1 (n=4500) had a home sampling kit mailed directly to their centrally registered home address; group 2 (n=4500) had a reply card mailed to their home address with which a home sampling kit could be ordered; and group 3 (n=21,439) had access to usual care. For women in groups 1 and 2, the relative risks of being tested were 4.1 (95% confidence interval [CI], 3.8-4.4) and 3.5 (95% CI, 3.2-3.9), respectively, compared with usual care. The corresponding figures for men were 19.1 (95% CI, 16.0-22.8) and 11.8 (95% CI, 9.8-14.2), respectively. Both screening strategies were highly effective, but men benefited the most from having the home sampling kit provided directly.
Andersen
Berit
B
Research Unit and Department of General Practice, Aarhus University, Aarhus C 8000, Denmark. ba@alm.au.dk
Olesen
Frede
F
Møller
Jens K
JK
Østergaard
Lars
L
D002690:Chlamydia Infections / Q000453:epidemiology*; D002692:Chlamydia trachomatis; D005260:Female; D052776:Female Urogenital Diseases / Q000453:epidemiology*; D006801:Humans; D008297:Male; D052801:Male Urogenital Diseases; D015995:Prevalence