title: Relationships between event-related potentials (P300) and activities of daily living in Parkinson's disease.
abstract: The correlation between event-related potentials (P300) and activities of daily living was studied in Parkinson's disease. The P300 of 30 patients with Parkinson's disease and 118 normal subjects were recorded. All patients were evaluated by the Mini-Mental State, Kana-hiroi Test, word fluency, Raven's Coloured Progressive Matrices, Osaka Memory Scale, revised Wechsler Adult Intelligence Scale, self-rating depression scale, state-trait anxiety inventory, and Functional Independence Measure. Eight patients showed prolonged P300 latencies. P300 latency showed relationships to the Mini-Mental State (p < 0.05) and cognitive items of the Functional Independence Measure (p < 0.05). P300 amplitude showed a relationship to performance IQ (p < 0.005), Raven's Coloured Progressive Matrices (p < 0.01) and motor items of the Functional Independence Measure (p < 0.05). It was concluded that P300 should be useful in predicting difficulties with activities of daily living in patients with Parkinson's disease.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Wakayama Medical University, Wakayama, Japan. maeshima@wakayama-med.ac.jp
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Maeshima
authors.forename: Toru
authors.initials: T
authors.lastname: Itakura
authors.forename: Norihiko
authors.initials: N
authors.lastname: Komai
authors.forename: Tomoko
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Akitaka
authors.initials: A
authors.lastname: Ueyoshi
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D018913:Event-Related Potentials, P300; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology*; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales