title: High-resolution CT of drug-induced lung disease.
abstract: Drug-induced pulmonary toxicity is increasing and early diagnosis is important because of the associated morbidity and mortality. Diagnosis is often difficult and is usually based on a history of drug therapy and exclusion of infection, radiation pneumonitis, and recurrence of the underlying disease. Although HRCT findings are frequently nonspecific, diagnosis can be facilitated by an understanding of the most common histopathologic and radiologic manifestations of drug-induced lung injury and knowledge of the drugs usually involved.
authors.affiliation: Department of Radiology, MD Anderson Cancer Center, Houston, Texas 77098, USA. jerasmus@di.mdacc.tmc.edu
authors.forename: Jeremy J
authors.initials: JJ
authors.lastname: Erasmus
authors.forename: H Page
authors.initials: HP
authors.lastname: McAdams
authors.forename: Santiago E
authors.initials: SE
authors.lastname: Rossi
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002317:Cardiovascular Agents / Q000009:adverse effects*; D018549:Cryptogenic Organizing Pneumonia / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced / Q000000981:diagnostic imaging; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging* / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D002317:Cardiovascular Agents