title: Synthesis of blood compatible polyamide block copolymers.
abstract: Blood compatibility of polyamides has been improved by introducing amido-amine groups in polymer backbone. Polyamide block-copolymer are synthesized by reacting amine end-capped polyamides with N,N'-methylene-bisacrylamide. Polyamide block-copolymers, thus produced found to have the ability of absorbing heparin. Heparinized polyamide block-copolymers have shown significant improvement in blood compatibility as evident from thrombus formation and hemolysis studies.
authors.affiliation: Centre for Biomedical Engineering, Indian Institute of Technology, New Delhi.
authors.forename: Jai Paul
authors.initials: JP
authors.lastname: Singhal
authors.forename: Alok R
authors.initials: AR
authors.lastname: Ray
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D001769:Blood; D006493:Heparin; D006801:Humans; D066298:In Vitro Techniques; D008422:Materials Testing; D015394:Molecular Structure; D009757:Nylons / Q000138:chemical synthesis* / Q000737:chemistry; D013057:Spectrum Analysis; D013499:Surface Properties; D013927:Thrombosis / Q000517:prevention & control; D014965:X-Rays
chemical_list: D001672:Biocompatible Materials; D009757:Nylons; D006493:Heparin