title: Molecular evidence that the aphid-transmitted Tomato mild mottle virus belongs to the Potyviridae family but not the Potyvirus genus.
abstract: Molecular studies have been carried out on Tomato mild mottle virus (TMMV) and 2322 nucleotides of the aphid-transmitted virus have been sequenced. This translates to a 2187 nucleotide open reading frame and a 135 nucleotide untranslated region (UTR) followed by a poly A tail. The sequence is consistent with the NIb and coat protein regions of a member of the Potyviridae family of viruses. Sequence comparisons show this virus to have no close relationship with any previously sequenced aphid-transmitted virus; the highest identity was found with the whitefly-transmitted Ipomoviruses. The vector of transmission and the low level of sequence identity with other aphid-transmitted viruses suggest TMMV does not belong to any existing genus of the Potyviridae family.
authors.affiliation: School of Biological Sciences, University of Bristol, UK.
authors.forename: W A
authors.initials: WA
authors.lastname: Monger
authors.forename: N J
authors.initials: NJ
authors.lastname: Spence
authors.forename: G D
authors.initials: GD
authors.lastname: Foster
mesh_terms: D000818:Animals; D001042:Aphids / Q000821:virology*; D018551:Solanum lycopersicum / Q000821:virology*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010935:Plant Diseases / Q000821:virology*; D019176:Potyviridae / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D017800:Potyvirus / Q000145:classification / Q000235:genetics; D012367:RNA, Viral / Q000032:analysis / Q000235:genetics; D017422:Sequence Analysis, DNA; D020506:Untranslated Regions
chemical_list: D012367:RNA, Viral; D020506:Untranslated Regions