Sepsis: menu of new approaches replaces one therapy for all.
Effective therapies for sepsis are being devised, after many failures. However, instead of a "one therapy for all" approach, management of sepsis will involve a menu of treatments, depending on the presence of inflammatory markers, the severity of disease, and other factors. This article looks at promising new therapies, including recombinant human activated protein C (rhAPC; drotrecogin alfa, Xigris), recently approved by the US Food and Drug Administration.
Larosa
Steven P
SP
Department of Infectious Diseases, The Cleveland Clinic Foundation, OH 44195, USA. larosas@ccf.org
D002986:Clinical Trials as Topic; D006801:Humans; D018805:Sepsis / Q000503:physiopathology* / Q000628:therapy*