[The clinical features of myocardial infarction in patients younger than 35 years and over 45 years of age].
OBJECTIVE
To investigate the clinical features and the characteristics of coronary angiography in young patients with myocardial infarction.


METHODS
27 patients younger than 35 years with myocardial infarction were studied with respect to their history, habit of smoking and drinking and body weight index. Comparison was made between the left ventricular ejection fraction with ultrasound method and X-ray heart/chest ratio in patients with or without thrombolytic therapy. Selective coronary angiography was performed in 23 of the 27 patients.


RESULTS
All of the 27 patients were male. 81.5% of them had smoking index more than 100, 55.5% drinking index more than 150, 51.9% family history of hypertension and 72.2% low blood level of HDL cholesterol. Most of the cardiac accidents took place in the night and morning. 17.4% of the patients had angiographically normal coronary arteries and 30.0% mild stenosis (no significant stenosis). 39.1%, 8.7% and 4.4% of the patients had one-vessel, two-vessel and three- vessel disease respectively. The frequency of patients with left ventricular ejection fraction less than 0.5 was 6.0% in patients with thrombolytic therapy and 33.3% without.


CONCLUSIONS
47.8% of the patients younger than 35 years with myocardial infarction has no or no significant stenosis of the coronary arteries. Heavy smoking is the most important one of relative factors for young patients with myocardial infarction. Other factors include low blood level of HDL cholesterol, drinking index of more than 150 and family history of hypertension in order. Thrombolysis treatment helps to maintain ventricular performance.
Dai
J
J
Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100037.
Gao
R
R
Chen
J
J
Yao
K
K
Yang
Y
Y
Qiao
S
S
Qin
X
X
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000209:etiology; D012907:Smoking / Q000009:adverse effects