title: [Testicular feminization, germinal tumor, NK lymphoma: what is the relationship?].
abstract: METHODS
  The authors report the case of a ten-year-old girl, who had been treated for a malignant germinal tumour five years before, presenting with a leukaemia-like syndrome associating bone pain, liver and spleen nodules and bone marrow involvement. The cyto-pathological analysis showed undifferentiated cells and CD56 and protein S100 were found as the only positive markers. The child received several subsequent lines of chemotherapy and ultimately died of the disease.
  
  
  CONCLUSIONS
  Particular cytogenetic abnormalities were observed (iso1q10, iso6p10) and were in favor of an unusual NK cell lymphoma.
  
  
  CONCLUSIONS
  This analysis revealed a XY genotype (testicular feminization syndrome).
authors.affiliation: Unité d'hémato-oncologie, hôpital des enfants, BP 3119, 31026 Toulouse, France.
authors.forename: M P
authors.initials: MP
authors.lastname: Castex
authors.forename: A I
authors.initials: AI
authors.lastname: Bertozzi
authors.forename: H
authors.initials: H
authors.lastname: Rubie
authors.forename: B
authors.initials: B
authors.lastname: Domenech
authors.forename: E
authors.initials: E
authors.lastname: Duchayne
authors.forename: J
authors.initials: J
authors.lastname: Selves
authors.forename: N
authors.initials: N
authors.lastname: Dastugue
authors.forename: M
authors.initials: M
authors.lastname: Danjoux
authors.forename: E
authors.initials: E
authors.lastname: Kulhein
authors.forename: P
authors.initials: P
authors.lastname: Galinier
authors.forename: A
authors.initials: A
authors.lastname: Robert
mesh_terms: D013734:Androgen-Insensitivity Syndrome / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D019002:CD56 Antigen / Q000235:genetics; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000473:pathology; D002648:Child; D005260:Female; D005838:Genotype; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology; D007938:Leukemia / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D009418:S100 Proteins / Q000235:genetics; D013724:Teratoma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology
chemical_list: D019002:CD56 Antigen; D009418:S100 Proteins