[Bone complication in diabetes subjects with good metabolic control and without longterm complications: certain problems. Part II. Basal parameters of bone turnover].
The resorption and osteogenesis equilibrium is commonly known basal condition of bone tissue homeostasis. For the purpose of bone turnover analysis in the group of good controlled diabetic patients without any diabetic complications basal biochemical parameters of osteogenesis and resorption were estimated. During low-calcium diet conditions both serum concentration and urine excretion of creatinine, hydroxyproline, hydroxylysine and uric acid were investigated. Serum alkaline phosphatase activity and oxalic acid urine excretion were also measured. As the result of the study the higher serum alkaline phosphatase activity and hydroksyproline urine excretion in type 1 diabetic patients as well as higher hydroxyproline and hydroxylysine urine excretion in type 2 diabetic patients were found.
Zywiec
J
J
Katedra i Kliniki Chorób Wewnetrznych i Diabetologii Slaskiej Akademii Medycznej w Zabrzu.
Grzeszczak
W
W
Pierzchała
K
K
D000469:Alkaline Phosphatase / Q000097:blood; D001862:Bone Resorption / Q000175:diagnosis / Q000209:etiology*; D003401:Creatine / Q000097:blood / Q000652:urine; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism*; D006801:Humans; D006901:Hydroxylysine / Q000097:blood / Q000652:urine; D006909:Hydroxyproline / Q000097:blood / Q000652:urine; D010012:Osteogenesis; D013997:Time Factors
D006901:Hydroxylysine; D000469:Alkaline Phosphatase; D003401:Creatine; D006909:Hydroxyproline