The role of dyslipidemia and statins in venous thromboembolism.
Recent studies have proposed an association between hyperlipidemia and venous thromboembolism (VTE). We review the epidemiological evidence linking dyslipidemia with VTE and examine several possible underlying mechanisms. We discuss the possible role of HMG CoA reductase inhibitors (statins) in the prevention and treatment of VTE and suggest future directions for research.
Ray
Joel G
JG
Department of Medicine, University of Toronto, Toronto, and Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. rayjg@mcmaster
Rosendaal
Frits R
FR