Nucleolomics: an inventory of the nucleolus.
In the January 8 issue of Current Biology, two papers from the Lamond and Mann laboratories describe the largest proteomics analysis to date of a cellular compartment, the nucleolus. As a byproduct of this tour de force, a novel nuclear compartment, the paraspeckles, was identified.
Dundr
Miroslav
M
National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Misteli
Tom
T
D000818:Animals; D002466:Cell Nucleolus / Q000502:physiology* / Q000648:ultrastructure; D006801:Humans; D009687:Nuclear Proteins / Q000032:analysis / Q000502:physiology*; D020543:Proteome
D009687:Nuclear Proteins; D020543:Proteome