[Pulmonary hyalinizing granuloma: a case report and a review of the literature].
OBJECTIVE
To highlight the characteristics of pulmonary hyalinizing granuloma (PHG).


METHODS
One patient with PHG confirmed by pathological assessment was presented and relevant literatures were reviewed.


RESULTS
PHG is a rare disease characterized by multiple bilateral pulmonary nodules. Symptoms include cough, dyspnea, chest pain, hemoptysis, fever and fatigue. Histologically, the nodules consist of haphazard or whorled arrays of lamellar, keloid - like collagen. Evidence suggests that the nodules are the result of a chronic exaggerated immune response.


CONCLUSIONS
PHG should be considered in patients showing multiple bilateral pulmonary nodules. The clinical course of PHG in most patients is benign. At present, there is no effective therapy.
Yang
J
J
Department of Respiratory, Anzhen Hospital, Capital University of Medical Science, Beijing 100029, China.
Liang
Y
Y
Liao
S
S
D017809:Fatal Outcome; D005260:Female; D015769:Granuloma, Respiratory Tract / Q000145:classification / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008168:Lung / Q000473:pathology*; D008875:Middle Aged