title: RWJ-333441 Microcide/RW Johnson.
abstract: Microcide and RW Johnson Pharmaceutical Research Institute are investigating a novel cephalosporin prodrug RWJ-333442 for the potential treatment of bacterial infections. RWJ-333442 is the prodrug of RWJ-333441; it has an improved solubility profile and studies are in progress in human serum, rats and rhesus macaques [382578], [382862], [383594].
authors.affiliation: Charles University Hospital, Department of Ophthalmology, Kralove, Czech Republic. kvasnicka@lfhk.cuni.cz
authors.forename: N
authors.initials: N
authors.lastname: Jiraskova
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002511:Cephalosporins / Q000494:pharmacology*; D007769:Lactams; D011355:Prodrugs / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D007769:Lactams; D011355:Prodrugs; C452865:RWJ-333441