title: Off-pump coronary artery bypass grafting for elderly patients.
abstract: BACKGROUND
  The use of off-pump coronary artery bypass grafting (CABG) has recently become widespread, and it has been proven to be less invasive and to facilitate early recovery. In this study, we investigated the efficacy of off-pump CABG for patients aged 75 years or more.
  
  
  METHODS
  A retrospective chart review was carried out for patients who underwent isolated off-pump and on-pump CABG at Shin-Tokyo Hospital between January 1997 and December 2000. The patients' demographic, operative data, and postoperative results were collected.
  
  
  RESULTS
  The off-pump group consisted of 60 men and 44 women with a mean age of 78.8 years, and the on-pump group consisted of 54 men and 20 women with a mean age of 77.6 years. Distal anastomoses were significantly fewer in the off-pump group (2.4 in off-pump group versus 3.7 in on-pump group), but total arterial bypass was more frequently achieved in off-pump group (82.7% versus 25.7%). Intubation time (8.4 versus 18.4 hours), intensive care unit stay (2.2 versus 3.5 days), and postoperative stay (13.8 versus 20.0 days) were significantly shorter in the off-pump group than in the on-pump group (p < 0.05). The frequency of the occurrence of major complications was significantly lower in the off-pump group than the on-pump group, especially in regard to postoperative stroke and respiratory failure (p < 0.05). Multivariate analysis showed that off-pump CABG significantly reduced patient recovery period and the incidence of postoperative complications. Early follow-up results, cardiac event-free and survival rates, did not significantly differ between the two groups.
  
  
  CONCLUSIONS
  Off-pump CABG is safe for the elderly patient. Off-pump CABG successfully facilitates early recovery and reduces the incidence of postoperative complications among elderly patients.
authors.affiliation: Department of Cardiovascular Surgery, Kobari General Hospital, Noda City, Chiba, Japan. genex@nifty.com
authors.forename: H
authors.initials: H
authors.lastname: Hirose
authors.forename: A
authors.initials: A
authors.lastname: Amano
authors.forename: A
authors.initials: A
authors.lastname: Takahashi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002315:Cardiopulmonary Bypass; D002423:Cause of Death; D015897:Comorbidity; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000401:mortality / Q000601:surgery*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D019060:Minimally Invasive Surgical Procedures; D009203:Myocardial Infarction / Q000401:mortality; D011183:Postoperative Complications / Q000401:mortality*; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis