[Individuated molecular target chemotherapy].
Developing the technological innovation for genomic and molecular biology rapidly, the strategy of molecular target chemotherapy for cancer is recognized in the medical circles to be defined on the basic science and the ethical society. The novel strategy of the individuated anticancer chemotherapy is growing of geno-projects to be determined of more effective and harmless therapeutic methods for every cancer patients by the individual difference of pharmacogenetics and molecular biology. The new strategy is dependent on the general analysis for the personal life science from pharmacokinetics, pharmacodynamics, and oncogenomics. We summarized the problems and the possibility of the translational research for these strategies from the position of medical oncology.
Yamamoto
Wataru
W
Department of Gastroenterology (Internal Oncology), Toyosu Hospital, Showa University.
Endo
Wataru
W
Sato
Atsushi
A
Matsukawa
Masaaki
M
D000970:Antineoplastic Agents / Q000008:administration & dosage; D020869:Gene Expression Profiling; D015894:Genome, Human; D023281:Genomics; D006801:Humans; D008967:Molecular Biology; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics; D010597:Pharmacogenetics; D010599:Pharmacokinetics
D000970:Antineoplastic Agents