title: Petrobactin, a photoreactive siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus.
abstract: Petrobactin is a bis-catecholate, alpha-hydroxy acid siderophore produced by the oil-degrading marine bacterium Marinobacter hydrocarbonoclasticus. The Fe(III)-complexed form of petrobactin is photoreactive in natural sunlight, mediated by the Fe(III)-citrate moiety. The reaction results in decarboxylation of the petrobactin ligand and reduction of Fe(III) to Fe(II). This report is one of the first to show the photoreactivity of Fe(III)-siderophores mediated by the ferric ion-alpha-hydroxy acid group. The demonstration of light-mediated decarboxylation of an Fe(III)-siderophore complex raises questions about a possible functional role for photoreactivity in siderophore-mediated iron uptake.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Barbeau
authors.forename: Guangping
authors.initials: G
authors.lastname: Zhang
authors.forename: David H
authors.initials: DH
authors.lastname: Live
authors.forename: Alison
authors.initials: A
authors.lastname: Butler
mesh_terms: D001549:Benzamides; D020563:Gammaproteobacteria / Q000737:chemistry / Q000378:metabolism*; D008401:Gas Chromatography-Mass Spectrometry; D019906:Nuclear Magnetic Resonance, Biomolecular; D010578:Petroleum / Q000378:metabolism*; D017262:Siderophores / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D001549:Benzamides; D010578:Petroleum; D017262:Siderophores; C450699:petrobactin