Homogeneity of asthma genome scan results.
Three different samples of families with asthmatic patients, the German data set and the CSGA data set subdivided into Caucasian and African American groups, were analyzed using the maximum lod score statistic. Although different scores were obtained in each sample, the Wald's likelihood homogeneity test did not reveal any significant genetic heterogeneity. This may be due to the very large variance of the model-free linkage statistics.
Babron
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INSERM U535, Batiment Gregory Pincus, 80 rue du Général Leclerc, 94276 Le Kremlin-Bicêtre, France.
Selinger-Leneman
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Dizier
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Clerget-Darpoux
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D000328:Adult; D000483:Alleles; D001249:Asthma / Q000453:epidemiology / Q000208:ethnology / Q000235:genetics*; D044383:Black People / Q000235:genetics; D002648:Child; D002874:Chromosome Mapping; D005787:Gene Frequency; D018740:Genetic Heterogeneity; D005819:Genetic Markers / Q000235:genetics; D005828:Genetics, Population; D016678:Genome; D005858:Germany; D006801:Humans; D008126:Lod Score; D008957:Models, Genetic; D044465:White People / Q000235:genetics; D001741:Black or African American
D005819:Genetic Markers