Neutrophils in anti-cancer immunological strategies: old players in new games.
This review highlights the new "immunological identity" of neutrophils within the cytokine network and their role in biology of diseases, particularly in tumor biology. The latest preclinical evidence of their involvement in anti-cancer immunotherapeutic and prophylactic strategies will be discussed with particular reference to the real possibilities of transferring experimental results to a clinical setting.
di Carlo
E
E
Department of Oncology and Neurosciences, G. d'Annunzio University of Chieti, 66100 Chieti, Italy.
Iezzi
M
M
Pannellini
T
T
Zaccardi
F
F
Modesti
A
A
Forni
G
G
Musiani
P
P
D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007167:Immunotherapy; D009369:Neoplasms / Q000473:pathology / Q000628:therapy*; D009504:Neutrophils / Q000276:immunology* / Q000378:metabolism / Q000502:physiology
D016207:Cytokines