title: [Clinical pathological study of lingual squamous cell carcinoma].
abstract: OBJECTIVE
  To investigate the pathological characteristics of lingual squamous cell carcinoma of younger patients under 40 years old.
  
  
  METHODS
  Routine histological examination and immunohistochemistry. Carcinoma tissues from patients over 70 years old were used as control.
  
  
  RESULTS
  In younger patients the grade II carcinoma was more common; tumor tissue was more invasive and there was more lymphnode metastasis than in old patients. Stronger p53 expression and weaker CK13 staining were more seen in young patients than old.
  
  
  CONCLUSIONS
  The lingual squamous cell carcinoma of young patients may be more aggressive than of old patients.
authors.affiliation: Department of Pathology, Peking University School of Stomatology, Beijing 100081, China.
authors.forename: X
authors.initials: X
authors.lastname: Han
authors.forename: Y
authors.initials: Y
authors.lastname: Gao
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology*; D003402:Creatine Kinase / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D014062:Tongue Neoplasms / Q000378:metabolism / Q000473:pathology*; D016159:Tumor Suppressor Protein p53 / Q000032:analysis
chemical_list: D016159:Tumor Suppressor Protein p53; D003402:Creatine Kinase