title: Typical carcinoid tumor of the larynx occurring with otalgia: a case report.
abstract: Neuroendocrine neoplasms of the larynx comprise a rare group of tumors that have a controversial history with regard to their classification. The World Health Organization categorizes these tumors as typical carcinoids, atypical carcinoids, small-cell neuroendocrine carcinomas, and paragangliomas. Atypical carcinoids and small-cell neuroendocrine carcinomas are the more common. Only 13 cases of typical carcinoid have been reported. Local excision is sufficient for typical carcinoids and paragangliomas, but atypical carcinoids require neck dissection because of their tendency to metastasize. Small-cell neuroendocrine carcinomas are not cured by local excision, and these patients have the worst prognosis (5-year survival: 5%); their treatment is limited to chemo- and radiotherapy. Because of these variations in tumor behavior and treatment, it is essential that otolaryngologists and pathologists to be able to correctly identify the specific type of tumor in order to optimize patient treatment and survival. We report a case of typical carcinoid and review the pertinent literature on this subject.
authors.affiliation: Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Kentucky College of Medicine, 800 Rose St., Lexington, KY 40536-0298, USA. j.cuzzourt@att.net
authors.forename: Jeremy C
authors.initials: JC
authors.lastname: Cuzzourt
authors.forename: John C
authors.initials: JC
authors.lastname: Pezold
authors.forename: C Warren
authors.initials: CW
authors.lastname: Dunn
mesh_terms: D001707:Biopsy, Needle; D002276:Carcinoid Tumor / Q000150:complications / Q000473:pathology* / Q000601:surgery; D004433:Earache / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D010148:Intractable Pain / Q000209:etiology; D012720:Severity of Illness Index; D016896:Treatment Outcome