title: Deficits in behavioral responding to regulatory challenges after lesions of ventrobasal thalamus in rats.
abstract: Electrolytic lesions of the posteromedial portion of the ventrobasal thalamic complex of rats impaired the feeding response to glucoprivation produced by systemic injection of 2-deoxy-D-glucose and the sodium appetite induced by injections of desoxycorticosterone, and produced abnormally low water intake in the absence of food. Drinking elicited by intracellular dehydration was not consistently affected. Lesions of the ventral anterior nucleus of the thalamus only impaired the feeding response to glucoprivation. The behavioral changes observed after posterior ventrobasal thalamic damage may be related to a disruption of gustatory, visceral, and somatosensory thalamic connections with the corpus striatum and neocortex.
authors.affiliation: Department of Psychology, Emory University, Atlanta, GA 30322, USA.
authors.forename: D B
authors.initials: DB
authors.lastname: Neill
authors.forename: J L
authors.initials: JL
authors.lastname: Kaufman
mesh_terms: D000818:Animals; D001066:Appetite / Q000502:physiology*; D001786:Blood Glucose / Q000378:metabolism*; D001931:Brain Mapping; D003342:Corpus Striatum / Q000502:physiology; D004435:Eating / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology; D008297:Male; D019579:Neocortex / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012965:Sodium Chloride / Q000008:administration & dosage*; D013649:Taste / Q000502:physiology; D020651:Ventral Thalamic Nuclei / Q000502:physiology*
chemical_list: D001786:Blood Glucose; D012965:Sodium Chloride