title: Homeotic regeneration of eye in amphibian tadpoles and its enhancement by vitamin A.
abstract: After removal of both the lateral eyes of external gill stage tadpoles of the toad Bufo melanostictus, the pineal organ gets transformed into a median eye. This type of transformation occurs in tadpoles of both control and vitamin A treated groups. However, vitamin A increases the likelihood of homeotic regeneration (57% in the control group and 71% in the vitamin A treated group). Histological studies showed that the newly transformed median eye developed from the pineal organ. The pineal eye so developed possessed all components of a normal eye such as a retina, sensory cells and lens.
authors.affiliation: Developmental Biology Laboratory, Department of Zoology, Dungar College, Bikaner 334 001, India. pca1@123India.com
authors.forename: O P
authors.initials: OP
authors.lastname: Jangir
authors.forename: D S
authors.initials: DS
authors.lastname: Shekhawat
authors.forename: A
authors.initials: A
authors.lastname: Prakash
authors.forename: K K
authors.initials: KK
authors.lastname: Swami
authors.forename: P
authors.initials: P
authors.lastname: Suthar
mesh_terms: D000818:Animals; D002025:Bufonidae / Q000254:growth & development*; D005801:Genes, Homeobox; D007814:Larva / Q000187:drug effects* / Q000502:physiology; D012038:Regeneration / Q000187:drug effects* / Q000235:genetics; D014801:Vitamin A / Q000494:pharmacology*
chemical_list: D014801:Vitamin A