title: Pulsed arterial spin labeling: comparison of multisection baseline and functional MR imaging perfusion signal at 1.5 and 3.0 T: initial results in six subjects.
abstract: Flow-alternating inversion-recovery magnetic resonance imaging was performed at 3.0 T to measure cerebral perfusion during rest and motor activation in six healthy adult volunteers. Results were compared with those at 1.5 T. The mean signal-to-noise ratio for both gray matter and white matter perfusion measured with and without vascular suppression at 3.0 T was significantly (P <.01) higher (n = 6) than that at 1.5 T. Brain perfusion activation maps collected during a motor task showed a substantially larger number of activated pixels (>80%) at 3.0 T, with activation in the supplementary motor area in the 3.0-T data that was not present on 1.5-T perfusion maps.
authors.affiliation: Laboratory of Functional and Molecular Imaging, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Martin N
authors.initials: MN
authors.lastname: Yongbi
authors.forename: Francesco
authors.initials: F
authors.lastname: Fera
authors.forename: Yihong
authors.initials: Y
authors.lastname: Yang
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Frank
authors.forename: Jeff H
authors.initials: JH
authors.lastname: Duyn
mesh_terms: D000328:Adult; D002536:Cerebral Arteries / Q000502:physiology*; D002560:Cerebrovascular Circulation; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male