Olanzapine-induced agranulocytosis: a case report and review of the literature.
The novel antipsychotic olanzapine has structural and pharmacological properties similar to clozapine. Until recently, no haematological toxicity has been reported with olanzapine use and it was expected to be a safer alternative. The authors report a case of agranulocytosis induced by olanzapine and reviewed the 11 cases reported in the literature.
Tolosa-Vilella
Carles
C
Department of Internal Medicine, Consorci Sanitari Parc Taulí, Sabadell, Barcelona, Spain. ctolosa@cspt.es
Ruiz-Ripoll
Ada
A
Mari-Alfonso
Begoña
B
Naval-Sendra
Elsa
E
D000380:Agranulocytosis / Q000097:blood / Q000139:chemically induced* / Q000503:physiopathology; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D010890:Pirenzepine / Q000009:adverse effects* / Q000031:analogs & derivatives
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine