Triterpenoids of the roots of Lavandula stoechas ssp. stoechas.
The roots of Lavandula stoechas ssp. stoechas afforded eleven known triterpenes, two steroids and two aromatics, in addition to two new triterpenes, 18-hydroxy-27-norolean-12,14-dien-30-al-28-oic acid and 3 beta-hydroxy-1-oxo-olean-12-ene-30-al-28-oic acid. Their structures were determined by spectroscopic analyses. The chloroform extract and some isolated compounds were evaluated for their growth inhibitory activity against several mammalian cell lines.
Topçu
G
G
Faculty of Pharmacy, University of Istanbul. Gulacti.Topcu@posta.mam.gov.tr
Ayral
M N
MN
Aydin
A
A
Gören
A C
AC
Chai
H B
HB
Pezzuto
J M
JM
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D027523:Lavandula / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D012997:Solvents; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D014407:Tumor Cells, Cultured; D014421:Turkey
D000972:Antineoplastic Agents, Phytogenic; D012997:Solvents; D014315:Triterpenes