title: The effect of midazolam premedication on discharge time in pediatric patients undergoing general anesthesia for dental restorations.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the effect of oral premedication with midazolam on recovery times of children undergoing dental restorations under general anesthesia.
  
  
  METHODS
  The records of 106 children (1.2-11.3 years, ASA I or II) undergoing ambulatory dental restorations were randomly selected and retrospectively reviewed: 50 subjects received midazolam (M) 0.5 mg/kg orally approximately 30 minutes prior to their procedure and 56 control subjects received no premedication (C). General anesthesia consisted primarily of inhalational anesthesia. Time in the operating room (OR), post-anesthesia care unit (PACU) and same day surgery (SDS) were determined and compared between groups.
  
  
  RESULTS
  Both groups were similar with respect to age and weight. There were no significant differences between groups in time spent in the OR, PACU or SDS (p>0.05). In a subset of children having shorter dental procedures (OR time < or =75 minutes, n=29), there remained no significant difference in discharge times between groups.
  
  
  CONCLUSIONS
  Preoperative administration of oral midazolam does not delay discharge of children undergoing general anesthesia for dental rehabilitation.
authors.affiliation: Department of Pediatric Dentistry, University of Utah School of Medicine, Primary Children's Medical Center, Salt Lake City, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Horgesheimer
authors.forename: C G
authors.initials: CG
authors.lastname: Pribble
authors.forename: R A
authors.initials: RA
authors.lastname: Lugo
mesh_terms: D000553:Ambulatory Care; D000556:Ambulatory Surgical Procedures; D000762:Anesthesia Recovery Period; D000766:Anesthesia, Dental; D000768:Anesthesia, General; D000769:Anesthesia, Inhalation; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003793:Dental Restoration, Permanent; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000627:therapeutic use*; D007223:Infant; D016014:Linear Models; D008297:Male; D008874:Midazolam / Q000008:administration & dosage / Q000627:therapeutic use*; D009294:Narcotics / Q000627:therapeutic use; D009873:Operating Rooms; D010351:Patient Discharge; D011229:Preanesthetic Medication; D011997:Recovery Room; D012189:Retrospective Studies; D013223:Statistics as Topic; D018709:Statistics, Nonparametric; D013997:Time Factors; D014081:Tooth Extraction
chemical_list: D006993:Hypnotics and Sedatives; D009294:Narcotics; D008874:Midazolam