title: Ochratoxin A in cereal-based baby foods: occurrence and safety evaluation.
abstract: Ochratoxin A is a typical cereal contaminant with strong nephrotoxic activity. To estimate the quantity of ochratoxin A that can be taken in by a child in the weaning period, several samples of cereal-based baby foods were analysed. Although most samples analysed contained ochratoxin A in undetectable amounts or below the Italian legal limit of 0.5 microg kg(-1), some irregular products were found. In particular, the analyses of the 119 batches (338 samples) of baby foods considered indicated that: 20 batches (16.8%) contained detectable quantities of ochratoxin A and four of these (3.4% of the total) contained ochratoxin A above the Italian permitted value. All samples coming from agricultural practices based on integrated pest management contained undetectable amounts of ochratoxin A, while approximately 5% of batches coming from conventional and organic agricultural practices were above the legal limit. On the basis of the established provisional tolerable weekly intake (PTWI), there is no significant toxicological risk for a child who occasionally consumes a formula with ochratoxin concentration slightly above the permitted level. However, stricter controls have to be applied to reject the batches containing irregular concentrations of ochratoxin A.
authors.affiliation: Laboratory Toxicology, Department of Pharmacological Sciences, University of Milan, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Beretta
authors.forename: R
authors.initials: R
authors.lastname: De Domenico
authors.forename: A
authors.initials: A
authors.lastname: Gaiaschi
authors.forename: C
authors.initials: C
authors.lastname: Ballabio
authors.forename: C L
authors.initials: CL
authors.lastname: Galli
authors.forename: C
authors.initials: C
authors.lastname: Gigliotti
authors.forename: P
authors.initials: P
authors.lastname: Restani
mesh_terms: D000383:Agriculture / Q000379:methods; D002523:Edible Grain / Q000737:chemistry*; D005504:Food Analysis / Q000379:methods; D005506:Food Contamination; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000032:analysis*; D009183:Mycotoxins / Q000008:administration & dosage / Q000032:analysis*; D009793:Ochratoxins / Q000008:administration & dosage / Q000032:analysis*; D018570:Risk Assessment
chemical_list: D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A