title: Synthesis of 2-alkyl-substituted-N6-methyladenine derivatives as potential adenosine receptor ligand.
abstract: 2-(1-Hexynyl), 2-((E)-1-hexenyl) and 2-(n-hexyl)-N6-methyladenines were synthesized, starting from 2-amino-6-chloropurine using palladium-catalyzed coupling as a key step as potential adenosine receptor ligand.
authors.affiliation: Division of Chemistry and Molecular Engineering, Seoul National University, Korea. hokim9@snu.ac.kr
authors.forename: H O
authors.initials: HO
authors.lastname: Kim
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D018047:Receptors, Purinergic P1 / Q000187:drug effects / Q000378:metabolism
chemical_list: D018047:Receptors, Purinergic P1; D000225:Adenine