title: [Color Doppler ultrasound and quantitative histologic study of angiogenesis in ovarian tumors].
abstract: OBJECTIVE
  To investigate whether there is any correlation between minimum resistance index (RImin) and microvessel density (MVD) in ovarian tumors.
  
  
  METHODS
  The intratumor artery RImin of 61 patients with ovarian tumor was measured by color doppler ultra-sound (CDU) preoperatively. MVD identified by von Willebrand factor was evaluated postoperatively. The relationship between RImin and MVD was analyzed.
  
  
  RESULTS
  Compared with the RImin of benign ovarian tumors, the RImin in ovarian cancers was significantly lower (P < 0.001). MVD of ovarian cancer was significantly higher than that of benign tumor both at a 100 magnification (P < 0.01) and a 400 magnification (P < 0.03). There was a significant negative correlation between RImin and MVD at a 100 magnification in benign group (r = -0.67, P < 0.01), in malignant group (r = -0.91, P < 0.01), and in both of groups (r = -0.84, P < 0.01).
  
  
  CONCLUSIONS
  Low RImin reflects high MVD in ovarian tumor.
authors.affiliation: Shandong Provincial Hospital, Jinan 250021, China.
authors.forename: X
authors.initials: X
authors.lastname: Wan
authors.forename: Y
authors.initials: Y
authors.lastname: Su
authors.forename: X
authors.initials: X
authors.lastname: Liu
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology; D018615:Ultrasonography, Doppler, Color / Q000379:methods*