title: Diterpenes and other constituents from Croton draco (Euphorbiaceae).
abstract: Croton draco (Euphorbiaceae) from Guadalupe, San José, Costa Rica was collected in July 1992 and phytochemically studied (leaves, seeds, wood, bark, sap and flowers separately). Commonly known compounds such as 1-hydroxyjunenol, p-hydroxybenzaldehyde, p-methoxybenzoic acid, 3,4,5-trimethoxycinnamyl alcohol, the coumarin scopoletin, the nor-terpenoids 9-dehydrovomifoliol and 2,3-dihydrovomifoliol were obtained. Taspine, two aporphinic alkaloids, the diterpenes 9(11)-dehydrokaurenic acid, hardwikiic acid, the corresponding new 12-oxo derivative as well as five clerodanes and a phorbol ester were also isolated. Three clerodanes were not previously described and their NMR spectroscopical data and MS fragmentation patterns are reported.
authors.affiliation: Escuela de Química and CIPRONA (Centro de Investigación de Productos Naturales), Universidad de Costa Rica, 2060, Costa Rica. renato@calzada.equi.ucr.ac.cr
authors.forename: R M
authors.initials: RM
authors.lastname: Murillo
authors.forename: J
authors.initials: J
authors.lastname: Jakupovic
authors.forename: J
authors.initials: J
authors.lastname: Rivera
authors.forename: V H
authors.initials: VH
authors.lastname: Castro
mesh_terms: D004224:Diterpenes / Q000032:analysis*; D019665:Euphorbiaceae / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D004224:Diterpenes