title: CAPD-associated peritonitis caused by Alcaligenes xylosoxidans sp. xylosoxidans.
abstract: Alcaligenes xylosoxidans is an uncommon cause of peritonitis in patients on maintenance continuous ambulatory peritoneal dialysis (CAPD). Peritonitis caused by A. xylosoxidans usually carries a poor prognosis because of the pathogen's virulence and its universal resistance to most antimicrobial agents. Even after early Tenckhoff catheter removal, the transport property of the peritoneum is often irreversibly damaged, leading to permanent technique failure. We report 2 patients with CAPD-associated peritonitis due to A. xylosoxidans sp. xylosoxidans who were successfully cured with a combination of piperacillin and tazobactam. One of them subsequently returned uneventfully to CAPD.
authors.affiliation: Department of Medicine, Queen Mary Hospital, University of Hong Kong, People's Republic of China.
authors.forename: S
authors.initials: S
authors.lastname: Tang
authors.forename: C C
authors.initials: CC
authors.lastname: Cheng
authors.forename: K C
authors.initials: KC
authors.lastname: Tse
authors.forename: F K
authors.initials: FK
authors.lastname: Li
authors.forename: B Y
authors.initials: BY
authors.lastname: Choy
authors.forename: T M
authors.initials: TM
authors.lastname: Chan
authors.forename: K N
authors.initials: KN
authors.lastname: Lai
mesh_terms: D000328:Adult; D000421:Alcaligenes; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D010397:Penicillanic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000188:drug therapy / Q000382:microbiology*; D010878:Piperacillin / Q000627:therapeutic use; D000078142:Tazobactam
chemical_list: D004791:Enzyme Inhibitors; D010406:Penicillins; D010397:Penicillanic Acid; D000078142:Tazobactam; D010878:Piperacillin