Wound healing effects of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica in rats.
The ethanolic extracts of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica were evaluated for their wound healing activity in rats. Wound healing activity was studied using excision and incision wound models in rats following topical application. Animals were divided into four groups with six in each group. Ten percent w/v extract of each plant was prepared in saline for topical application. H. indicum possesses better wound healing activity than P. zeylanicum and A. indica. Tensile strength results indicate better activity of H. indicum on remodeling phase of wound healing.
Reddy
J Suresh
JS
University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506 009 AP, India.
Rao
P Rajeswara
PR
Reddy
Mada S
MS
D000818:Animals; D004353:Drug Evaluation, Preclinical / Q000379:methods / Q000706:statistics & numerical data; D019665:Euphorbiaceae / Q000737:chemistry; D005260:Female; D028162:Heliotropium / Q000737:chemistry; D008297:Male; D008954:Models, Biological; D008517:Phytotherapy / Q000379:methods / Q000706:statistics & numerical data; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D029606:Plumbaginaceae / Q000737:chemistry; D051381:Rats; D011917:Rats, Inbred Lew; D013536:Suture Techniques; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology
D010936:Plant Extracts