The 677C-->T mutation of the methylene-tetrahydrofolate reductase gene in the pathogenesis of osteonecrosis of the femoral head.
Zalavras
Charalampos G
CG
Department of Orthopedic Surgery, LAC + USC Medical Center, University of Southern California, Los Angeles, USA.
Malizos
Konstantinos N
KN
Dokou
Eleni
E
Vartholomatos
George
G
D000328:Adult; D000483:Alleles; D019943:Amino Acid Substitution; D003062:Codon / Q000235:genetics; D005260:Female; D005271:Femur Head Necrosis / Q000235:genetics*; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006115:Greece / Q000453:epidemiology; D006720:Homozygote; D006801:Humans; D020138:Hyperhomocysteinemia / Q000235:genetics; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D020125:Mutation, Missense; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000172:deficiency / Q000235:genetics*; D017354:Point Mutation; D012307:Risk Factors; D019851:Thrombophilia / Q000235:genetics
D003062:Codon; D000587:Oxidoreductases Acting on CH-NH Group Donors; D042965:Methylenetetrahydrofolate Reductase (NADPH2)