Transient pseudohypoaldosteronism with hyponatremia-hyperkalemia in infant urinary tract infection.
OBJECTIVE
We describe an uncircumcised male infant and a female neonate treated for infant urinary tract infection who had multiple hormonal and electrolyte abnormalities consistent with the diagnosis of transient pseudohypoaldosteronism.


METHODS
We retrospectively reviewed these 2 cases.


RESULTS
In each case successful treatment of infant urinary tract infection was accompanied by the resolution of all hormonal and electrolyte abnormalities, including hyperaldosteronemia, hyperreninemia, hyponatremia and hyperkalemia.


CONCLUSIONS
Because of future renal scarring, decreased renal function and possible hypertension, appropriate hormonal studies should be performed in infants with infant urinary tract infection who also have hyponatremia and hyperkalemia.
Schoen
Edgar J
EJ
Department of Genetics and Division of Research, Kaiser Permanente Medical Care Program of Northern California, Oakland 94611-5693, USA.
Bhatia
Suruchi
S
Ray
G Thomas
GT
Clapp
Wesley
W
To
Trinh T
TT
D002944:Circumcision, Male; D005260:Female; D006801:Humans; D006947:Hyperkalemia / Q000209:etiology* / Q000503:physiopathology; D007010:Hyponatremia / Q000209:etiology* / Q000503:physiopathology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011546:Pseudohypoaldosteronism / Q000150:complications* / Q000503:physiopathology; D012189:Retrospective Studies; D013997:Time Factors; D014552:Urinary Tract Infections / Q000150:complications* / Q000628:therapy