Incidence of primary extranodal lymphoma involving gastrointestinal tract by histological type at Ilorin.
We report 21 cases of primary extranodal lymphoma of the gastrointestinal tract over a period of 10 years (1986-1995) at the Department of Morbid Anatomy and Histopathology, University of Ilorin Teaching Hospital, Ilorin, Kwara State of Nigeria. This represents 6% of the total gastrointestinal tract malignancies diagnosed during same period. All were Non Hodgkin's Lymphoma. The ages ranged from 4 to 60 years, while the mean age was 23 years. Male to female ratio was 4:3. The anatomic sites involved were stomach 4, (19%), small intestine 13, (62%), and large intestine 4, (19%). There was no single case of rectal lymphoma. The histological types were Burkitt's lymphoma 9 (42.8%), diffuse mixed (small and large) cells 4 (19.1%), diffuse large cells 4 (9.1%), small lymphocytic cells, 2 (9.5%) and large immunoblastic cells 2 (9.5%). All the cases of Burkitt's lymphoma occurred under 20 years of age. Distribution into prognostic groups (grades) according to working formulation for clinical usage was low grade, 2 (9.5%), intermediate grade, 8 (38.1%) and High grade, 22 (52.4%). We conclude that extranodal malignant lymphoma involving the gastrointestinal tract is not rare and should be considered for differential diagnosis in gastrointestinal tract malignancies.
Afolayan
E A
EA
Department of Morbid Anatomy and Histopathology, University of Ilorin Teaching Hospital, Ilorin, Nigeria.
Anjorin
A S
AS
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002051:Burkitt Lymphoma / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000145:classification* / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000453:epidemiology; D008223:Lymphoma / Q000145:classification* / Q000453:epidemiology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000453:epidemiology; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000453:epidemiology; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D012189:Retrospective Studies; D017678:Sex Distribution