title: A hemodialysis patient with trazodone-induced parkinsonism.
abstract: A hemodialysis male patient exhibited depressive symptoms and trazodone was prescribed orally. Although his depressive symptoms disappeared, he gradually presented with parkinsonism. His parkinsonism improved within a week after stopping trazodone. The clinical course strongly suggested that it was induced by trazodone. However, there is no report on antidopaminergic side effects of parkinsonism. This case suggests that antidopaminergic effects leading to parkinsonism need to be considered in patients on hemodialysis that are taking trazodone.
authors.affiliation: Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, Tokyo, Japan. fukunisi@prit.go.jp
authors.forename: Isao
authors.initials: I
authors.lastname: Fukunishi
authors.forename: Tateki
authors.initials: T
authors.lastname: Kitaoka
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Shirai
authors.forename: Kyono
authors.initials: K
authors.lastname: Kino
authors.forename: Emiko
authors.initials: E
authors.lastname: Kanematsu
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Sato
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects*; D003863:Depression / Q000188:drug therapy*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D020734:Parkinsonian Disorders / Q000139:chemically induced*; D006435:Renal Dialysis; D014196:Trazodone / Q000009:adverse effects*
chemical_list: D018687:Antidepressive Agents, Second-Generation; D014196:Trazodone