[Dynamic left ventricular obstruction associated with a pheochromocytoma reversible after tumor ablation].
The association of dynamic left ventricular outflow tract obstruction and pheochromocytoma is rare with only about fifteen previously reported cases in the literature. The association may be the result of chronic increased catecholamine secretion which induces intra-ventricular obstruction in a hypertrophied ventricle due to hypertension. The authors report a new case in which the intraventricular gradient on Doppler echocardiography was particularly high at 120 mmHg. The gradient totally regressed after removal of the pheochromocytoma. The finding of a systolic murmur in a patient with pheochromocytoma should lead to the prescription of Doppler echocardiography and diagnosis of left ventricular tract obstruction must lead to the association of betablocker and alphablocker therapy before surgery. The removal of the pheochromocytoma is usually followed by the complete regression of left intraventricular obstruction, as in this case.
Gallet
B
B
Service de cardiologie, centre hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prudhon, 95107 Argenteuil.
Quintard
H
H
Fruchaud
J
J
Hiltgen
M
M
D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000601:surgery*; D002395:Catecholamines / Q000378:metabolism / Q000494:pharmacology; D003937:Diagnosis, Differential; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008875:Middle Aged; D010673:Pheochromocytoma / Q000150:complications* / Q000601:surgery*; D018487:Ventricular Dysfunction, Left / Q000209:etiology*; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery
D002395:Catecholamines