[Comparison between therapeutic effect of Risperidone in treating different traditional Chinese medicine syndrome types of first-episode schizophrenia].
OBJECTIVE
To study the therapeutic effect, side effects and cognize improvement of Risperidone in treating different TCM Syndrome-types of first-episode schizophrenia.


METHODS
Applying Risperidone to treat first-episode schizophrenics who were divided into Phlegm-Dampness type, Phlegm-Fire type and other types in TCM, and observing them with PANSS, TESS and Wisconsin Card Sorting Test (WCST).


RESULTS
It is important to assess the therapeutic effect of patient with Fire Syndrome or without. Insomnia is the most prevalent side effect, while akathisia in Phlegm-Fire type is the most serious side effect, cognition deficiency in Phlegm-Dampness type is the most serious before treatment, and reduction of total card number of WCST in Phlegm-Fire type is significant after treatment (P < 0.05).


CONCLUSIONS
It is the best way to use Risperidone combined with TCM Syndrome Differentiation so as to elevate the efficacy.
Cao
X
X
Beijing Anding Hospital, Capital University of Medical Sciences, Beijing (100088).
Wang
W
W
D000293:Adolescent; D000328:Adult; D003937:Diagnosis, Differential; D018492:Dopamine Antagonists / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*; D012702:Serotonin Antagonists / Q000627:therapeutic use
D018492:Dopamine Antagonists; D012702:Serotonin Antagonists; D018967:Risperidone