title: Beesiosides A-F, six new cycloartane triterpene glycosides from Beesia calthaefolia.
abstract: Six new cycloartane triterpene glycosides (1-6), beesiosides A-F, were isolated from whole plants of Beesia calthaefolia, and their structures were elucidated on the basis of extensive NMR experiments and chemical methods. Beesiosides A-F were assigned as (20S,24R)-epoxy-9,19-cyclolanostane-3beta,16beta,18,25-tetraol-3-O-beta-D-xylopyranoside (1), (20S,24R)-epoxy-9,19-cyclolanostane-3beta,12beta,16beta,18,25-pentaol-3-O-beta-D-xylopyranoside (2), (20S,24R)-epoxy-9,19-cyclolanostane-3beta,12alpha,16beta,18,25-pentaol-3-O-beta-D-xylopyranoside (3), (20S,24R)-16beta-acetoxy-20,24-epoxy-9,19-cyclolanostane-3beta,12alpha,18,25-tetraol-3-O-beta-D-xylopyranoside (4), (20S,24R)-epoxy-9,19-cyclolanostane-3beta,15alpha,16beta,18,25-pentaol-3-O-beta-D-xylopyranoside (5), and (20S,24R)-16beta-acetoxy-20,24-epoxy-9,19-cyclolanostane-3beta,12beta,25-triol-3-O-beta-D-xylopyranoside (6), respectively.
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, People's Republic of China. jianhuaju@hotmail.com
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Ju
authors.forename: Dong
authors.initials: D
authors.lastname: Liu
authors.forename: Geng
authors.initials: G
authors.lastname: Lin
authors.forename: Xu-dong
authors.initials: XD
authors.lastname: Xu
authors.forename: Bing
authors.initials: B
authors.lastname: Han
authors.forename: Jun-shan
authors.initials: JS
authors.lastname: Yang
authors.forename: Guang-zhong
authors.initials: GZ
authors.lastname: Tu
authors.forename: Li-bin
authors.initials: LB
authors.lastname: Ma
mesh_terms: D002855:Chromatography, Thin Layer; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D006868:Hydrolysis; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D029626:Ranunculaceae / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D006027:Glycosides; D012503:Saponins; D014315:Triterpenes; C085352:cycloartane