title: Diffusion- and perfusion-weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM).
abstract: To monitor changes of brain tissue metabolism in acute demyelinating encephalitis (ADEM), we examined a patient with suspected ADEM by serial MRI including diffusion- and perfusion-weighted imaging (DWI, PWI). Within the inflammatory tissue, the apparent diffusion coefficients were reduced, normal, and increased. Perfusion varied between reduced and normal values, except for small hyperperfused regions. Combining standard MRI with DWI and PWI may elucidate different overlapping phases in cerebral inflammation.
authors.affiliation: Department of Medical Informatics, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Berlin, Germany. bernarding@ukbf.fu-berlin.de
authors.forename: Johannes
authors.initials: J
authors.lastname: Bernarding
authors.forename: Jürgen
authors.initials: J
authors.lastname: Braun
authors.forename: Hans-Christian
authors.initials: HC
authors.lastname: Koennecke
mesh_terms: D000328:Adult; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis* / Q000378:metabolism*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male