Drosophila windpipe codes for a leucine-rich repeat protein expressed in the developing trachea.
The embryonic tracheal system of Drosophila provides an important model for understanding the process of epithelial branching morphogenesis. Here we report the sequence and expression analysis of a novel tracheal gene, named windpipe (wdp). wdp is identical to the predicted gene CG3413 and encodes a transmembrane, leucine-rich repeat family member. wdp transcripts appear abruptly at stage 15 and are restricted to primary tracheal branches that give rise to secondary branches.
Huff
Janice L
JL
Department of Biological Sciences, University of Nevada Las Vegas, 4505 Maryland Parkway, Las Vegas, NV 89154-4004, USA. jhuff@ccmail.nevada.edu
Kingsley
Karl L
KL
Miller
Jennell M
JM
Hoshizaki
Deborah K
DK
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D004625:Embryo, Nonmammalian; D018507:Gene Expression Regulation, Developmental; D007930:Leucine; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D020449:Repetitive Sequences, Amino Acid; D014132:Trachea / Q000196:embryology* / Q000378:metabolism
D029721:Drosophila Proteins; D008565:Membrane Proteins; C456267:wdp protein, Drosophila; D007930:Leucine