Chronic sensory neuronopathy associated with human T-cell lymphotropic virus type I infection.
We described two patients with chronic sensory neuronopathy who had anti-HTLV-I antibody in serum and cerebrospinal fluid but no signs of myelopathy. A sural nerve specimen revealed severe degeneration of myelinated and unmyelinated axons. The second patient had subclinical Sjögren's syndrome suggestive of a possible link among human T-cell lymphotropic virus type I (HTLV-I), Sjögren's syndrome and sensory neuronopathy, respectively. The broad spectrum of neurologic disorders associated with HTLV-I infection now would include chronic sensory neuronopathy.
Shimazaki
Rie
R
Third Department of Internal Medicine, Oita Medical University, Hasama 1-1, 879-5593, Oita, Japan.
Ueyama
Hidetsugu
H
Mori
Toshio
T
Mori
Miyuki
M
Fujimoto
Shin
S
Kumamoto
Toshihide
T
Tsuda
Tomiyasu
T
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001706:Biopsy; D016516:CD4-CD8 Ratio; D048429:Cell Size; D002908:Chronic Disease; D005260:Female; D015490:HTLV-I Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D009431:Neural Conduction; D010523:Peripheral Nervous System Diseases / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D012021:Reflex, Abnormal; D012217:Rheumatoid Factor / Q000097:blood; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis; D013497:Sural Nerve / Q000473:pathology
D000914:Antibodies, Viral; D012217:Rheumatoid Factor