T(2)-shortening by strongly magnetized spheres: a chemical exchange model.
It is shown that a chemical exchange model can reproduce nuclear magnetic relaxation caused by diffusion of water molecules near strongly magnetized particles. The agreement is based on the similarity (but not equivalence) of the respective "visit-limiting" mechanisms in the echo-limited regime. The model leads to a single equation that predicts relaxation behavior in both the motional-averaging and visit-limited regimes. When combined with the static-dephasing regime equation, the result is a simple theory (for spheres) that covers the entire range of diffusion times.
Brooks
Rodney A
RA
Neuroimaging Branch, NINDS, National Institutes of Health, Bethesda, Maryland, USA. RodneyABrooks@cs.com
D004058:Diffusion; D005110:Extracellular Space / Q000378:metabolism; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008432:Mathematical Computing; D008962:Models, Theoretical