title: Highlights of latest American College of Cardiology and American Heart Association Guidelines for Management of Patients with Acute Myocardial Infarction.
abstract: The recently published American College of Cardiology/American Heart Association Guidelines for the Management of Patients with Acute Myocardial Infarction stress 3 major points: (1) the prehospital phase from the onset of symptoms to definitive therapy in the emergency department must be shortened by 50% in order to reduce further the estimated 30% mortality rate for all patients in the community who suffer an acute myocardial infarction; (2) a more widespread use of thrombolytic agents is warranted because of the demonstrated, extremely time-dependent benefit to survivorship: the sooner it is given, the better the outcome; and (3) the administration of aspirin (160-325 mg) daily for an indefinite period is perhaps the most important therapy for a patient with acute myocardial infarction. Long-term therapy with lipid-lowering Statin drugs and angiotensin-converting enzyme inhibitor agents are gaining increasing evidence-based data to support their perpetual use as well.
authors.affiliation: Boston Medical Center, Boston University School of Medicine, Boston, MA 02118, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Ryan
authors.forename: Rowlens M
authors.initials: RM
authors.lastname: Melduni
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000572:American Heart Association; D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008790:Metoprolol / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000175:diagnosis / Q000628:therapy*; D017410:Practice Guidelines as Topic; D014336:Troponin / Q000097:blood
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D015415:Biomarkers; D005343:Fibrinolytic Agents; D014336:Troponin; D006493:Heparin; D003402:Creatine Kinase; D008790:Metoprolol; D001241:Aspirin