Apolipoprotein E and diets: a case of gene-nutrient interaction?
Apolipoprotein E has key functions in lipoprotein metabolism, and polymorphisms in the apolipoprotein E gene are associated with distinct lipoprotein patterns. The possibility of gene-nutrient interactions for apolipoprotein E has been addressed in many studies. Although results have generally been mixed, the indications for such an interaction have been more common in studies employing a metabolic challenge. Studies directly designed to examine apolipoprotein E gene-nutrient interactions are needed.
Rubin
Jill
J
Department of Medicine, Columbia University, New York, New York, USA.
Berglund
Lars
L
D000818:Animals; D001057:Apolipoproteins E / Q000235:genetics* / Q000378:metabolism; D004042:Dietary Fats, Unsaturated / Q000378:metabolism; D006801:Humans; D008074:Lipoproteins / Q000097:blood / Q000378:metabolism*; D009747:Nutritional Physiological Phenomena / Q000502:physiology*; D011110:Polymorphism, Genetic; D019518:Postprandial Period / Q000502:physiology
D001057:Apolipoproteins E; D004042:Dietary Fats, Unsaturated; D008074:Lipoproteins