[Ophthalmologic manifestations of systemic vasculitis: report of six cases and review of the literature].
OBJECTIVE
Study of characteristics of ocular involvement in systemic vasculitis.


METHODS
We describe six cases of systemic vasculitis with ocular involvement observed between 1992 and 2000. These cases are compared with those reported in the literature.


RESULTS
Our patients suffered from Wegener's granulomatosis (four cases), periarteritis nodosa and Churg-Strauss syndrome. Ocular manifestations were conjunctivitis, scleritis, orbital pseudotumor, optic neuritis and extraocular muscle palsy. These manifestations are similar to those reported in the literature. Their treatment requires steroids and immunosuppressive drugs. In one of our cases, intravenous immunoglobulins were effective in controlling an optic neuritis.


CONCLUSIONS
Ocular involvement in systemic vasculitis may concern any orbital structure. It usually occurs during the course of vasculitis but may be one of its first manifestations. It requires an appropriate treatment to prevent ophthalmic complications and especially blindness.
Delarbre
X
X
Service de médecine interne, hôpital Gabriel-Montpied, BP 69, 63003 Clermont-Ferrand, France.
André
M
M
Dalens
H
H
Delèvaux
I
I
Lhoste-Trouilloud
A
A
Tridon
A
A
Schmidt
J
J
Chanet
V
V
Piette
J C
JC
Aumaître
O
O
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D005128:Eye Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008875:Middle Aged; D009902:Optic Neuritis / Q000188:drug therapy / Q000209:etiology; D014657:Vasculitis / Q000150:complications*
D000305:Adrenal Cortex Hormones; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents