Delayed graft function. Influence on outcome and strategies for prevention.
Delayed graft function remains a prevalent problem in cadaveric renal transplantation that increases rejection, decreases graft and patient survival, increases the cost of transplantation, and complicates patient management. Although current medical and surgical strategies can reduce the incidence of DGF to 20% or less, newer therapies that focus on nonimmune and immune forms of renal injury are needed to improve outcomes further.
Shoskes
D A
DA
Departments of Urology and Renal Transplantation, Cleveland Clinic Florida, Weston, Florida, USA. dshoskes@urol.com
Shahed
A R
AR
Kim
S
S
D006084:Graft Rejection / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D006085:Graft Survival / Q000502:physiology*; D006801:Humans; D007674:Kidney Diseases / Q000503:physiopathology / Q000601:surgery*; D016030:Kidney Transplantation; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome