title: [Illustration of elasticity differences using MR-elastography].
abstract: Differences of elasticity in tissue phantoms with inclusions of different elasticity were mapped by means of MR elastography (MRE). This new magnetic resonance imaging technique is based on the phase shift of the MR signal by switching a motion sensitizing magnetic field gradient simultaneously with the coupling of a shear wave. Wave patterns showing snapshots of the shear wave that propagates through the investigated substance were depicted in tomographic phase images. It was investigated wether a visualization of differences in elasticity of soft tissues was possible on the basis of differences in the wavelength. For this purpose, tissue phantoms with cylindrical inclusions were produced from agar gels, with agar concentrations between 1.0 and 1.5%. The diameters of the inclusions were of the order of a few centimetres. For diameters as small as 4 cm, there were still distinct differences in the wavelength between the matrix and the inclusion. The results of our study suggest that this technique has the potential for future application as an additional imaging method for tumor detection.
authors.affiliation: Sektion für Experimentelle Kemspinresonanz des ZNS, Abteilung für Neuroradiologie, Eberhard-Karls-Universität Tübingen.
authors.forename: U
authors.initials: U
authors.lastname: Hamhaber
authors.forename: F A
authors.initials: FA
authors.lastname: Grieshaber
authors.forename: J
authors.initials: J
authors.lastname: Nagel
authors.forename: U
authors.initials: U
authors.lastname: Klose
mesh_terms: D000362:Agar; D004548:Elasticity; D005782:Gels; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis; D019047:Phantoms, Imaging; D013314:Stress, Mechanical
chemical_list: D005782:Gels; D000362:Agar