[The effects of the polysaccharides from Dermatocarpon miniatum on oxygen radicals and lipid peroxidation].
OBJECTIVE
To study the effects of Dermatocarpon miniatum (DEM) polysaccharides scavenging oxygen radicals and inhibiting lipid peroxidation.


METHODS
.OH was produced by Fenton reaction and O2-. was produced by the oxidation of pyrogallol. The inhibition to LPO was determined by the colorimetry for testing the relative content of MDA.


RESULTS
DEM polysaccharides could scavenge oxygen radical. The amounts of scavenging 50% (EC50) .OH was 1.72 mg/ml, the EC50 for O2-. was 2.12 mg/ml. DEM polysaccharides could also decrease the content of MDA.


CONCLUSIONS
DEM polysaccharides has the effects of scavenging oxygen radicals and the inhibition to LPO. Its activities showed positive correlation with the amounts.
Jin
J
J
Xi'an Jiao Tong University, Xi'an 710061.
Bian
X
X
Ge
P
P
Jing
H
H
Ding
L
L
Ding
D
D
D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology*; D008011:Lichens / Q000737:chemistry*; D015227:Lipid Peroxidation / Q000187:drug effects*; D011134:Polysaccharides / Q000008:administration & dosage / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism*
D000975:Antioxidants; D011134:Polysaccharides; D017382:Reactive Oxygen Species