title: [The role of opisthorchiasis in development of the secondary neurocirculatory dystonia and myocardial metabolic changes].
abstract: OBJECTIVE
  Clarification of opisthorchiasis role in development of secondary neurocirculatory dystonia (NCD) and assessment of myocardial condition in patients with chronic opisthorchiasis (CO) with consideration of the disease duration and intensity of opisthorchotic invasion.
  
  
  METHODS
  The trial enrolled 120 patients with CO, 35 patients with cardial NSD and 33 healthy controls.
  
  
  RESULTS
  In long history of opisthorchiasis and severe invasion, autonomic cardiovascular regulation was abnormal. If CO patients have NCD, myocardial 99mTc-pyrophosphate scintigraphy reveals diffuse metabolic lesion of the myocardium. Long-term autonomic dysregulation of the cardiovascular system in CO and absence of adequate therapy lead to formation of progressive autonomic imbalance syndrome with sympathetic hypertonicity provoking metabolic disturbances of the myocardium.
authors.forename: L I
authors.initials: LI
authors.lastname: Tiukalova
authors.forename: I N
authors.initials: IN
authors.lastname: Posokhov
authors.forename: E I
authors.initials: EI
authors.lastname: Beloborodova
authors.forename: A S
authors.initials: AS
authors.lastname: Alekseeva
mesh_terms: D000328:Adult; D009202:Cardiomyopathies / Q000209:etiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009449:Neurocirculatory Asthenia / Q000209:etiology* / Q000503:physiopathology; D009889:Opisthorchiasis / Q000150:complications*