title: Nonoperative management of acute spinal cord injury.
abstract: Advances in transport, imaging, and stabilization of the injured patient have made the topic of acute management more important than ever in patients with spinal cord injury. Optimal treatment requires prompt delivery of care for life-threatening respiratory and hemodynamic events in a manner that will not further damage the unstable spinal elements. The application of these treatment principles broadly to injured patients is necessitated by our inability to determine, on an acute basis, those patients who might eventually recover meaningful neurologic function from those who will not. Therefore, nonoperative management of acute spinal cord injury requires consideration of two goals: 1) the preservation of the patient's life and 2) optimizing the potential for recovery of neurologic function. The first consideration requires not only an understanding of the novel systemic consequences of spinal cord injury but also of treatments directed at combating them. The second includes the application of resuscitative measures without further damaging the spinal cord and, in some cases, the use of traction and immobilization. In the past these efforts were aimed primarily at increasing the survival rate of patients with spinal cord injury, whereas current care may also play an important role in the eventual recovery of neurologic function. Despite many advances in our understanding of the basic mechanisms of paralysis, clinical management of spinal cord injury remains a significant challenge and one that requires continuing efforts at improving acute and postacute therapies.
authors.affiliation: Department of Neurological Surgery, Laboratory for Spinal Cord Injury Repair, Loyola University Medical Center, 2160 South First Avenue, Maywood, Illinois 60153, USA. rnockel@lumc.edu
authors.forename: R P
authors.initials: RP
authors.lastname: Nockels
mesh_terms: D000208:Acute Disease; D004632:Emergency Medical Services; D006439:Hemodynamics; D006801:Humans; D007103:Immobilization; D007442:Intubation, Intratracheal; D009460:Neurologic Examination; D003668:Pressure Ulcer / Q000209:etiology / Q000517:prevention & control; D013119:Spinal Cord Injuries / Q000150:complications / Q000628:therapy*; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control