[A new approach to cholesterol].
Although much is known about hypercholesterolemia and the associated risk for the development of atherosclerosis, very little research has focused on altered cholesterol biosynthesis. Recent discovery that the biochemical basis for the human malformation syndrome, Smith-Lemli-Opitz syndrome appears to lie in altered cholesterol biosynthesis has changed this situation. Cholesterol has an extraordinary important functions in organism. Recommendations to lower serum cholesterol are widespread, yet low serum cholesterol is associated with poorly understood morbidity. Cholesterol is still an enigmatic, essential metabolite and much remains to learn about it.
Bzdúch
V
V
I. detská klinika Detskej fakultnej nemocnice, Bratislava, SR. bzduch@inmail.sk
Behúlová
D
D
Kajaba
I
I
D002784:Cholesterol / Q000096:biosynthesis / Q000172:deficiency / Q000378:metabolism*; D006801:Humans; D006937:Hypercholesterolemia / Q000378:metabolism
D002784:Cholesterol