title: RanBP1, a velocardiofacial/DiGeorge syndrome candidate gene, is expressed at sites of mesenchymal/epithelial induction.
abstract: RanBP1, a velocardiofacial syndrome/DiGeorge syndrome candidate gene, is expressed in the frontonasal processes, branchial arches, aortic arches, and limb buds. At these sites, RanBP1 apparently coincides with neural crest-derived mesenchymal cells. In addition, RanBP1 is expressed in the forebrain as well as in hindbrain regions previously associated with crest-derived mesenchymal cells.
authors.affiliation: Department of Cell and Molecular Physiology and UNC Neuroscience Center, CB#7545, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Maynard
authors.forename: Gloria T
authors.initials: GT
authors.lastname: Haskell
authors.forename: Naina
authors.initials: N
authors.lastname: Bhasin
authors.forename: James M
authors.initials: JM
authors.lastname: Lee
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Gassman
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Lieberman
authors.forename: Anthony-Samuel
authors.initials: AS
authors.lastname: LaMantia
mesh_terms: D000818:Animals; D001011:Aorta / Q000196:embryology; D004062:DiGeorge Syndrome / Q000235:genetics; D004627:Embryonic Induction / Q000235:genetics; D004848:Epithelium / Q000196:embryology*; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D018878:Limb Buds; D008648:Mesoderm; D051379:Mice; D008813:Mice, Inbred ICR; D009687:Nuclear Proteins / Q000235:genetics* / Q000378:metabolism; D020931:ran GTP-Binding Protein / Q000235:genetics* / Q000378:metabolism
chemical_list: D009687:Nuclear Proteins; C091775:ran-binding protein 1; D020931:ran GTP-Binding Protein