title: Enzymatically cleavable linker groups in polymer-supported synthesis.
abstract: Access to broadly applicable linker groups that are stable under a variety of reaction conditions and enable the release of target compounds from polymeric supports under the mildest conditions is a major goal in combinatorial chemistry. Here, we summarize the development of enzymatically cleavable linker groups used to prepare a variety of different target molecules on polymeric supports.
authors.affiliation: Max-Planck-Institut für Molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Strasse 11, D-44227 Dortmund, Germany.
authors.forename: Reinhard
authors.initials: R
authors.lastname: Reents
authors.forename: Duraiswamy A
authors.initials: DA
authors.lastname: Jeyaraj
authors.forename: Herbert
authors.initials: H
authors.lastname: Waldmann
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D004798:Enzymes / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011487:Protein Conformation
chemical_list: D004798:Enzymes; D011108:Polymers