title: Assessment of knee cartilage in cadavers with dual-detector spiral CT arthrography and MR imaging.
abstract: OBJECTIVE
  To assess dual-detector spiral CT arthrography in the evaluation of the entire knee cartilage obtained from cadavers.
  
  
  METHODS
  Two independent observers characterized articular cartilage in 12 cadaver knees in which MR imaging and dual-detector spiral CT arthrography were performed and compared their findings to those found during macroscopic assessment. The sensitivity and specificity of MR imaging and spiral CT arthrography for detecting grade 2A or higher and grade 2B or higher cartilage lesions, the Spearman correlation coefficient between arthrographic and macroscopic grading, and kappa statistics for assessing interobserver reproducibility were determined.
  
  
  RESULTS
  At spiral CT arthrography, sensitivities and specificities ranged between 80% and 88% for the detection of grade 2A or higher cartilage lesions and ranged between 85% and 94% for the detection of grade 2B or higher cartilage lesions. At MR imaging, sensitivities and specificities ranged between 78% and 86% and between 76% and 91% for the detection of grade 2A or higher and grade 2B or higher cartilage lesions, respectively. Spearman correlation coefficients between spiral CT arthrography or MR imaging and macroscopic grading of articular surfaces were 0.797 and 0.702, respectively.
  
  
  CONCLUSIONS
  Dual-detector spiral CT arthrography of the knee is a valuable method for the assessment of open cartilage lesions of the entire knee.
authors.affiliation: Department of Radiology, Cliniques Universitaires St Luc, Université Catholique de Louvain, 10 av Hippocrate, 1200 Brussels, Belgium. vandeberg@rdgn.ucl.ac.be
authors.forename: Bruno C
authors.initials: BC
authors.lastname: Vande Berg
authors.forename: Frédéric E
authors.initials: FE
authors.lastname: Lecouvet
authors.forename: Pascal
authors.initials: P
authors.lastname: Poilvache
authors.forename: Jacques
authors.initials: J
authors.lastname: Jamart
authors.forename: Roland
authors.initials: R
authors.lastname: Materne
authors.forename: Benoit
authors.initials: B
authors.lastname: Lengele
authors.forename: Baudouin
authors.initials: B
authors.lastname: Maldague
authors.forename: Jacques
authors.initials: J
authors.lastname: Malghem
mesh_terms: D000368:Aged; D001175:Arthrography / Q000379:methods*; D002102:Cadaver; D002358:Cartilage, Articular / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed