The influence of vitamin B2 intake on the activation coefficient of erythrocyte glutation reductase in the elderly.
OBJECTIVE
To evaluate the influence of dietetic vitamin B2 on the activation coefficient of erythrocyte glutation reductase (alpha-EGR) of a group of elderly people.


METHODS
The study subjects were 133, independently-living elderly people, between 65 and 90 years of age. A dietetic study was performed using a 7-day food record. Riboflavin status was measured by determining the alpha-EGR.


RESULTS
Some 23.9% of subjects had riboflavin intakes lower than those recommended. At the biochemical level, 9.8% of subjects (7.7% of men and of 10.6% women) showed alpha-EGR>1.2. Those subjects with riboflavin intakes below 90% of those recommended showed significantly higher alpha-EGR levels (1.15+/-0.16), an indication of a poorer riboflavin status at the biochemical level. Those with greater intakes showed lower alpha-EGR values (1.05+/-0.10). Furthermore, the mean consumption of dairy products (an important source of this vitamin) by subjects is insuficiente (341.1+/-159.8 g/day, 2.1+/-1 servings/day). The data show that those with riboflavin intakes below those recommended took 204.7+/-89.4 g/day of milk products (1.3+/-0.5 servings/day) compared to the 384+/-153.1 g/day (2.4+/-1 servings/day) (p<0.001) consumed by those with higher riboflavin intakes.


CONCLUSIONS
Although the mean riboflavin intake is acceptable, there remain some insufficiencies that require attention. It would seem advisable to recommend the elderly increase their intake of milk products. This would be especially important for subjects who take less than two rations per day.
López-Sobaler
A M
AM
Departamento de Nutrición, Facultad de Farmacia, Universidad Complutense de Madrid, Spain. asobaler@farm.ucm.es
Ortega
R M
RM
Quintas
M E
ME
Navarro
A R
AR
Aparicio
A
A
Gomez-Rodriguez
N
N
Cocho
M
M
Requejo
A M
AM
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism*; D015930:Diet Records; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005980:Glutathione Reductase / Q000032:analysis*; D006801:Humans; D008297:Male; D009752:Nutritional Status / Q000187:drug effects; D011446:Prospective Studies; D012256:Riboflavin / Q000032:analysis*; D013030:Spain
D005980:Glutathione Reductase; D012256:Riboflavin