title: [Lichen sclerosus et atrophicus--diagnostic and therapeutic difficulties].
abstract: The aim of the study was clinical and therapeutic analysis of 61 cases of lichen sclerosus et atrophicus of LSA observed in the last 5 years (1994-1999). The study revealed that lesions in women were usually localized in extragenital areas in contrast to men who had genital changes. Various therapeutic methods were used according to localization and the extent of skin changes. It appears that surgical procedure (circumcision) is the method of first choice in the case of LSA involving preputial area. Systemic therapy with Piascledine and vitamin E seems to be the most efficacious in LSA localized in genital and extragenital skin regions in women. Taking into consideration many diagnostic errors committed by non-dermatologist clinical diagnosis, especially in lesions involving sexual organs, should be confirmed by histopathological examination.
authors.affiliation: Katedry i Kliniki Dermatologii Slaskiej Akademii Medycznej w Katowicach.
authors.forename: L A
authors.initials: LA
authors.lastname: Brzezińska-Wcisło
authors.forename: G T
authors.initials: GT
authors.lastname: Szeremeta-Bazylewicz
authors.forename: E K
authors.initials: EK
authors.lastname: Pierzchała
authors.forename: K
authors.initials: K
authors.lastname: Gilek
authors.forename: D
authors.initials: D
authors.lastname: Urbańska
authors.forename: A
authors.initials: A
authors.lastname: Walaszek
authors.forename: D
authors.initials: D
authors.lastname: Wcisło
authors.forename: S
authors.initials: S
authors.lastname: Figurski
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003879:Dermatologic Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000175:diagnosis / Q000628:therapy; D012737:Sex Factors; D014845:Vulvar Diseases / Q000175:diagnosis / Q000628:therapy
chemical_list: D003879:Dermatologic Agents