Characterization of AC mode scanning ion-conductance microscopy.
A scanning ion-conductance microscope (SICM) with a vibrating probe has been recently developed (vSICM). In this system, the amplitude of the AC ionic current is detected by using a lock-in amplifier locked to the vibration frequency of the probe. Such a scheme allows for a better control of the tip position because the AC ionic current is more sensitive to the probe-surface distance than the DC ionic current used previously. In this paper, we demonstrate the utility of this technique to the imaging of topographically rough specimens and high-resolution imaging over selected small areas. We also show that it is possible to record the DC ionic current simultaneously during the scan, which can reveal additional information not apparent in the images obtained with the AC ionic current.
Pastré
D
D
Department of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, Charlottesville 22908-0736, USA.
Iwamoto
H
H
Liu
J
J
Szabo
G
G
Shao
Z
Z
D004553:Electric Conductivity; D008853:Microscopy / Q000379:methods*