title: Adenocarcinoma of the nonpigmented ciliary epithelium: report of two cases with immunohistochemical findings.
abstract: BACKGROUND
  Acquired neoplasms arising from the nonpigmented ciliary epithelium (NPCE) are much less common than uveal melanocytic proliferations. We report two cases of acquired neoplasms arising from the NPCE with immunohistochemical findings.
  
  
  METHODS
  Case reports.
  
  
  CONCLUSIONS
  Patient 1 was a 39-year-old man who presented with a pigmented mass behind the iris and secondary exudative retinal detachment. The eye also developed neovascular glaucoma. Patient 2 was a 44-year-old woman with a ciliary body mass but without symptoms. Both of these tumors were classified histologically as low-grade adenocarcinomas of the NPCE from specimens successfully removed by iridocyclectomy. Immunohistochemical findings confirmed the origin of the tumor cells; however, some changes in the immunoreactivity to cytokeratin AE1 and epithelial membrane antigen were found.
authors.affiliation: Department of Ophthalmology, Nagoya University School of Medicine, Japan. terasaki@med.nagoya-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Terasaki
authors.forename: T
authors.initials: T
authors.lastname: Nagasaka
authors.forename: M
authors.initials: M
authors.lastname: Arai
authors.forename: T
authors.initials: T
authors.lastname: Harada
authors.forename: Y
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D002924:Ciliary Body / Q000473:pathology*; D004847:Epithelial Cells; D005260:Female; D006801:Humans; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D014604:Uveal Neoplasms / Q000473:pathology*