Preterm premature rupture of the fetal membranes complicated by oligohydramnios.
Preterm premature rupture of the fetal membranes complicated by oligohydramnios may have significant impact and sequelae on pregnancy outcome. In this article the role of amniotic fluid in fetal development, especially lung development, is reviewed; complications resulting from oligohydramnios are outlined; and the evaluated therapeutics and management schemes are delineated.
Spong
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Pregnancy and Perinatology Branch, Center for Research for Mothers and Children, NICHD, National Institutes of Health, Bethesda, Maryland, USA. spongc@exchange.nih.gov
D000653:Amniotic Fluid / Q000502:physiology; D005314:Embryonic and Fetal Development; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology; D016104:Oligohydramnios / Q000209:etiology* / Q000628:therapy; D011247:Pregnancy; D011256:Pregnancy Outcome; D012307:Risk Factors