title: Bacterial meningoencephalitis in patients undergoing chronic hemodialysis: two case reports.
abstract: Two patients with bacterial meningoencephalitis (BME) undergoing chronic hemodialysis (HD) are reported. Patient 1 died of bacterial empyema caused by Streptococcus intermedius. Patient 2 was successfully treated by intravenous vancomycin (VCM), panipenem-betamipron and intrathecal VCM. Enterococcus avium from a sacral decubitus ulcer was suggested as a possible pathogen of BME in Patient 2. Autopsy findings in Patient 1 and antimicrobial options in Patient 2 are discussed with a review of the literature. In the two BME patients presented here, sepsis played an important role in their pathogenesis during the chronic HD state.
authors.affiliation: Department of Internal Medicine, Miyazaki Prefectural Hospital of Nobeoka, 882-0835, Miyazaki, Japan.
authors.forename: Chie
authors.initials: C
authors.lastname: Fujimoto
authors.forename: Shogo
authors.initials: S
authors.lastname: Yazawa
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Matsuoka
authors.forename: Akira
authors.initials: A
authors.lastname: Ishihara
authors.forename: Mariko
authors.initials: M
authors.lastname: Hayami
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Kawasaki
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016983:Enterococcus / Q000302:isolation & purification / Q000472:pathogenicity; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008590:Meningoencephalitis / Q000209:etiology* / Q000382:microbiology*; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D013290:Streptococcal Infections / Q000209:etiology* / Q000473:pathology; D013291:Streptococcus / Q000302:isolation & purification / Q000472:pathogenicity
chemical_list: D000900:Anti-Bacterial Agents