[The relationship between prostate cancer and multi-estimating results of prostate-specific antigen].
OBJECTIVE
To analyze the relationship between prostate cancer and multi-estimating results of prostate-specific antigen (PSA).


METHODS
In accordance with the results of 76 cases checked on PSA over 2 years, univariate and multivariate analysis were performed in prostate cancer connected with PSA, PSA density (PSAD), PSA velocity (PSAV), age-specific PSA (PSA-age), and free to total PSA ratio (fPSA/tPSA) by means of t test, Chi-square test, and logistic regression.


RESULTS
Of the 76 cases observed, 16 were diagnosed with prostate cancer. By univariate analysis, all factors of PSA, PSAD, PSAV, age-PSA and fPSA/t PSA showed conspicuous correlations with prostate cancer. However, in multivariate analysis, only did fPSA/t PSA (P = 0.006) with regressive ratio being positive number and PSAD (P = 0.018) with regressive ratio being negative number reveal statistical differences with prostate cancer.


CONCLUSIONS
In multi-estimating results of PSA, fPSA/t PSA as a risk factor and PSAD as a protective factor were more correspondant with the principle for screen test of prostate cancer.
Wang
Y
Y
Department of Urology, General Hospital, Bengang Iron & Steel Co, Benxi 117000, China.
Huang
C
C
Zhang
J
J
D000368:Aged; D016009:Chi-Square Distribution; D005163:Factor Analysis, Statistical; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017430:Prostate-Specific Antigen; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D012307:Risk Factors
D017430:Prostate-Specific Antigen