title: Endophthalmitis associated with extrusion of a ganciclovir implant.
abstract: OBJECTIVE
  To report a case of endophthalmitis with associated scleral defect after intravitreal positioning of a ganciclovir implant.
  
  
  METHODS
  Interventional case report. A 39-year-old woman developed acute endophthalmitis 1 month after insertion of a ganciclovir implant. The eye was enucleated.
  
  
  RESULTS
  Pathologic examination of the enucleated globe revealed an intrascleral location of the implant suture tab and a vitreous abscess.
  
  
  CONCLUSIONS
  Intraocular infection resulted from a scleral gap containing a foreign body (surgical implant). Appropriate surgical techniques should minimize the risk of ganciclovir implant extrusion.
authors.affiliation: Department of Ophthalmology, New York University Medical Center, New York, New York 100116, USA. norman.charles@med.nyu.edu
authors.forename: Norman C
authors.initials: NC
authors.lastname: Charles
authors.forename: Lars
authors.initials: L
authors.lastname: Freisberg
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy; D000208:Acute Disease; D000328:Adult; D000998:Antiviral Agents; D017726:Cytomegalovirus Retinitis / Q000188:drug therapy; D004343:Drug Implants / Q000009:adverse effects*; D009877:Endophthalmitis / Q000175:diagnosis / Q000209:etiology*; D015353:Eye Enucleation; D005260:Female; D005548:Foreign-Body Migration / Q000150:complications* / Q000175:diagnosis; D015774:Ganciclovir; D006801:Humans; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000209:etiology*
chemical_list: D000998:Antiviral Agents; D004343:Drug Implants; D015774:Ganciclovir