title: Additional wide resection of malignant soft tissue tumors.
abstract: Forty-five patients with soft tissue sarcomas received additional wide resections after they were treated with simple excision by a primary physician. Of the patients in the current study, 26 were male and 19 were female; all were treated between 1986 and 1998 for malignant soft tissue tumors. The mean followup was 7.1 +/- 3.4 years. The mean time from first excision to additional wide resection was 8 weeks, and for 90% of the patients it was within 12 weeks. In deciding the surgical margin for an additional operation, enhanced computed tomography scans and magnetic resonance images were done. Four (8.8%) patients had local recurrences that required a second resection and had no evidence of disease at latest followup. Four (8.8%) patients had distant metastases but did not have local recurrences. Three patients died of lung metastases. The overall 5-year survival rate of the patients was 93%, and the overall 5-year disease-free rate was 84%. It seems that tumors treated adequately by wide resection in an additional operation have results as good as tumors treated with a primary wide resection.
authors.affiliation: Nagoya University School of Medicine, Department of Orthopaedic Surgery, Japan.
authors.forename: Hideshi
authors.initials: H
authors.lastname: Sugiura
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Takahashi
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Katagiri
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nishida
authors.forename: Hiroatsu
authors.initials: H
authors.lastname: Nakashima
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yonekawa
authors.forename: Hisashi
authors.initials: H
authors.lastname: Iwata
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002648:Child; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D012509:Sarcoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D012680:Sensitivity and Specificity; D012983:Soft Tissue Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D013514:Surgical Procedures, Operative / Q000379:methods*; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome