MEN-10700 menarini.
Menarini is investigating the penem beta-lactam antibiotic, MEN-10700, for the potential control of bacterial infections. MEN-10700 compares favorably with other oral beta-lactams against Haemophilus influenzae strains as well as other respiratory pathogens [341073]. The compound has also showed activity against multiple drug-resistant Gram-negative pathogens [341074]. MEN-10700 has a broad spectrum of activity against Gram-positive and Gram-negative bacteria and demonstrates a potency greater than that of imipenem [174404].
Jiraskova
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Charles University Hospital, Department of Ophthalmology, Kralove, Czech Republic. kvasnicka@lfhk.cuni.cz
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D007769:Lactams; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D007769:Lactams; C106870:Men 10700