title: The effect of indigenous Neem Azadirachta indica [correction of (Adirachta indica)] mouth wash on Streptococcus mutans and lactobacilli growth.
abstract: Neem is one of the most widely researched tropical tree, with almost all it's parts being put for a variety of uses. In the present study, the antibacterial effect of Neem mouthwash against salivary levels of streptococcus mutans and lactobacillus has been tested over a period of 2 months. Also it's effect in reversing incipient carious lesions was assessed. While streptococcus mutans was inhibited by Neem mouthwashes, with or without alcohol as well as chlorhexidine, lactobacillus growth was inhibited by chlorhexidine alone. The initial data appears to prove it's effect in inhibiting S. mutans and reversing incipient carious lesions, longer term clinical trials are essential.
authors.affiliation: Dept. of Pedodontics & Preventive Dentistry, College of Dental Surgery, Manipal 570 119, India.
authors.forename: A
authors.initials: A
authors.lastname: Vanka
authors.forename: S
authors.initials: S
authors.lastname: Tandon
authors.forename: S R
authors.initials: SR
authors.lastname: Rao
authors.forename: N
authors.initials: N
authors.lastname: Udupa
authors.forename: P
authors.initials: P
authors.lastname: Ramkumar
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002648:Child; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use; D015169:Colony Count, Microbial; D003731:Dental Caries / Q000517:prevention & control; D003777:Dental Prophylaxis; D000431:Ethanol / Q000627:therapeutic use; D005500:Follow-Up Studies; D005989:Glycerides / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007194:India; D007778:Lactobacillus / Q000187:drug effects* / Q000254:growth & development; D009067:Mouthwashes / Q000627:therapeutic use*; D014677:Pharmaceutical Vehicles; D010919:Placebos; D010938:Plant Oils / Q000008:administration & dosage / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000737:chemistry*; D012463:Saliva / Q000382:microbiology; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000187:drug effects* / Q000254:growth & development; D013729:Terpenes / Q000008:administration & dosage / Q000627:therapeutic use*; D014197:Trees / Q000737:chemistry
chemical_list: D000891:Anti-Infective Agents, Local; D005989:Glycerides; D009067:Mouthwashes; D014677:Pharmaceutical Vehicles; D010919:Placebos; D010938:Plant Oils; D013729:Terpenes; D000431:Ethanol; C002443:neem oil; D002710:Chlorhexidine