[Activity of glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R) and superoxide dismutase in the brain tumors].
The aim of the study was to estimate the activity of glutathione peroxydase, glutathione reductase and superoxide dysmutase in the brain tumours. The activity of GSH-Px was evaluated with the use of spectrophotometry, GSSG-R was evaluated based on the Mize and Langdon method, and SOD-1 with Sykes et al. method. The 55 specimens (45 specimens of neoplasm and 10 specimens of healthy brain tissue) were studied. The statistical analysis revealed significant increase of enzymes within the brain tumours in comparison to the healthy brain tissue.
Dudek
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Klinika Neurochirurgii Akademii Medycznej w Białymstoku. lebkowski@usa.net
Farbiszewski
R
R
Michno
T
T
Łebkowski
W J
WJ
Kozłowski
A
A
D001932:Brain Neoplasms / Q000201:enzymology* / Q000601:surgery; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism*; D005980:Glutathione Reductase / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013482:Superoxide Dismutase / Q000378:metabolism*
D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase