title: Accidental monensin toxicosis in horses in Mozambique.
abstract: Horses on several farms in Mozambique were inadvertently fed with a concentrate containing 69 ppm monensin. The horses developed acute signs of toxicity and several died. The animals were depressed, anorectic and paretic before death. Epistaxis was observed in 1 case. Petechial haemorrhages were present in the muscles, heart, lungs, gastrointestinal tract and spleen in 3 horses necropsied. No significant histopathological cardiac and skeletal muscle lesions were seen, except in 1 case, in which there was focal loss of myofibrils.
authors.affiliation: Department of Pathology, Faculty of Veterinary Medicine, University of Utrecht, The Netherlands. c.bila@vet.uu.nl
authors.forename: C G
authors.initials: CG
authors.lastname: Bila
authors.forename: C L
authors.initials: CL
authors.lastname: Perreira
authors.forename: E
authors.initials: E
authors.lastname: Gruys
mesh_terms: D000821:Animal Feed / Q000506:poisoning; D000818:Animals; D004305:Dose-Response Relationship, Drug; D006734:Horse Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000401:mortality / Q000473:pathology; D006736:Horses; D007476:Ionophores / Q000506:poisoning*; D008985:Monensin / Q000506:poisoning*; D009073:Mozambique / Q000453:epidemiology; D018482:Muscle, Skeletal / Q000473:pathology; D009206:Myocardium / Q000473:pathology
chemical_list: D007476:Ionophores; D008985:Monensin