title: Echinodolides A and B, new cembrane diterpenoids with an eight-membered lactone ring from the leaves of Echinodorus macrophyllus.
abstract: Two new cembrane diterpenoids with an eight-membered lactone ring, echinodolides A (1) and B (2), were isolated from the leaves of the Brazilian medicinal plant Echinodorus macrophyllus ("Chapéu-de-couro"), and the structures and relative stereochemistry were elucidated from their spectroscopic data.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Shigemori
authors.forename: Sayaka
authors.initials: S
authors.lastname: Shimamoto
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Sekiguchi
authors.forename: Ayumi
authors.initials: A
authors.lastname: Ohsaki
authors.forename: Jun'ichi
authors.initials: J
authors.lastname: Kobayashi
mesh_terms: D001938:Brazil; D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D019684:Magnoliopsida / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
chemical_list: D004224:Diterpenes; D007783:Lactones; C449852:echinodolide A; C449853:echinodolide B