Role of hematopoietic growth factors in angiogenesis.
In early ontogeny, hematopoiesis is closely associated with angiogenesis. This article reviews recent studies of the effect of hematopoietic growth factors on several endothelial cell functions together with recent findings about angiogenesis and antiangiogenic therapies in hematopoietic malignancies such as leukemia, lymphoma and myeloma.
Ribatti
D
D
Department of Human Anatomy and Histology, University of Bari Medical School, Bari, Italy. ribatti@antomia.uniba.it
Vacca
A
A
De Falco
G
G
Ria
R
R
Roncali
L
L
Dammacco
F
F
D000818:Animals; D004730:Endothelium, Vascular / Q000378:metabolism / Q000502:physiology; D019337:Hematologic Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D006410:Hematopoiesis / Q000276:immunology / Q000502:physiology; D016298:Hematopoietic Cell Growth Factors / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D009389:Neovascularization, Pathologic / Q000188:drug therapy / Q000503:physiopathology / Q000517:prevention & control; D018919:Neovascularization, Physiologic / Q000187:drug effects / Q000502:physiology*
D016298:Hematopoietic Cell Growth Factors