Synthesis of furo[2,3b]furans and furo[2,3b]pyrans via rhodium-catalyzed tandem hydroformylation/acetalization.
[reaction: see text] Rhodium-catalyzed tandem hydroformylation/acetalization of alpha,omega-alkenediols gives facile access to perhydrofuro[2,3b]furans and perhydrofuro[2,3b]pyrans in good yields. Similarly, benzoannelated tetrahydrofuro[2,3b]furans are obtained by hydroformylation of o-hydroxy cinnamyl alcohols.
Roggenbuck
Rafael
R
Fachbereich Chemie, Organische Chemie I, Universität Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.
Schmidt
Andreas
A
Eilbracht
Peter
P
D000107:Acetylation; D000438:Alcohols / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry; D000478:Alkylation; D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis*; D011714:Pyrans / Q000138:chemical synthesis*; D012238:Rhodium
D000438:Alcohols; D000475:Alkenes; D005663:Furans; D011714:Pyrans; D012238:Rhodium