Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles.
Bursavich
Matthew G
MG
Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Rich
Daniel H
DH
D016282:Aspartic Acid Endopeptidases / Q000737:chemistry; D001665:Binding Sites; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D018716:Molecular Mimicry; D010455:Peptides / Q000737:chemistry*; D011480:Protease Inhibitors / Q000737:chemistry; D011485:Protein Binding; D011487:Protein Conformation; D013329:Structure-Activity Relationship
D004791:Enzyme Inhibitors; D008024:Ligands; D010455:Peptides; D011480:Protease Inhibitors; D016282:Aspartic Acid Endopeptidases