title: Growth hormone responses to repeated maximal cycle ergometer exercise at different pedaling rates.
abstract: The present study examined the growth hormone (GH) response to repeated bouts of maximal sprint cycling and the effect of cycling at different pedaling rates on postexercise serum GH concentrations. Ten male subjects completed two 30-s sprints, separated by 1 h of passive recovery on two occasions, against an applied resistance equal to 7.5% (fast trial) and 10% (slow trial) of their body mass, respectively. Blood samples were obtained at rest, between the two sprints, and for 1 h after the second sprint. Peak and mean pedal revolutions were greater in the fast than the slow trial, but there were no differences in peak or mean power output. Blood lactate and blood pH responses did not differ between trials or sprints. The first sprint in each trial elicited a serum GH response (fast: 40.8 +/- 8.2 mU/l, slow: 20.8 +/- 6.1 mU/l), and serum GH was still elevated 60 min after the first sprint. The second sprint in each trial did not elicit a serum GH response (sprint 1 vs. sprint 2, P < 0.05). There was a trend for serum GH concentrations to be greater in the fast trial (mean GH area under the curve after sprint 1 vs. after sprint 2: 1,697 +/- 367 vs. 933 +/- 306 min x mU(-1) x l(-1); P = 0.05). Repeated sprint cycling results in an attenuation of the GH response.
authors.affiliation: Department of Physical Education, Sports Science and Recreation Management, Loughborough University, Loughborough, Leicestershire LE11 3TU, United Kingdom.
authors.forename: K A
authors.initials: KA
authors.lastname: Stokes
authors.forename: M E
authors.initials: ME
authors.lastname: Nevill
authors.forename: G M
authors.initials: GM
authors.lastname: Hall
authors.forename: H K A
authors.initials: HK
authors.lastname: Lakomy
mesh_terms: D000328:Adult; D001642:Bicycling / Q000502:physiology*; D001810:Blood Volume / Q000502:physiology; D005080:Exercise Test; D019382:Human Growth Hormone / Q000097:blood*; D006801:Humans; D008297:Male; D009994:Osmolar Concentration; D013997:Time Factors
chemical_list: D019382:Human Growth Hormone