[The development and application of computer-aided bone histomorphometry system].
The aim of this study is to develop a Computer-aided Bone Histomorphometry System. The method is based on the Micro-graphical Digital System composed of microscope, digital camera, computer and related programs. The methodology was developed to measure the basic data on each image of visual field of hard bone tissue with computer-assistance. Following this, the parameters of bone volume, bone structure and bone metabolism were calculated based on the standardization of bone histomorphometry. Such method has been used in the experimental and clinical studies of osteoporosis to predict the fracture risk and evaluate the drug effect.
Tang
T
T
Department of Orthopaedics, Shanghai Ninth People's Hospital, Shanghai Second Medical University, Shanghai 200011.
Dai
K
K
Gu
D
D
Xue
W
W
Liao
W
W
D015519:Bone Density; D001842:Bone and Bones / Q000033:anatomy & histology* / Q000378:metabolism; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation; D010024:Osteoporosis / Q000175:diagnosis; D012984:Software