Prenatal ultrasonographic diagnosis of nasal bone abnormalities in three fetuses with Down syndrome.
Facial abnormalities are common in neonates with Down syndrome. This report describes nasal bone abnormalities in 3 unselected fetuses with Down syndrome detected prenatally by ultrasonography. Two of the fetuses had ultrasonographically undetectable nasal bones and 1 had a nasal bone measurement that was below the 2.5th percentile of the normal distribution for that gestational age.
Sonek
Jiri D
JD
Department of Obstetrics and Gynecology, Ohio State University, Dayton, Ohio, USA.
Nicolaides
Kypros H
KH
D000328:Adult; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging; D004314:Down Syndrome / Q000175:diagnosis*; D005260:Female; D006801:Humans; D009295:Nasal Bone / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D011296:Prenatal Diagnosis; D016216:Ultrasonography, Prenatal