title: Postanoxic generalized dystonia improved by bilateral Voa thalamic deep brain stimulation.
abstract: A patient with severe postanoxic dystonia and bilateral necrosis of the basal ganglia, who was confined to a wheelchair, underwent bilateral ventralis oralis anterior deep brain stimulation (Voa-DBS) after 6 weeks of unsuccessful bilateral pallidal DBS (GPi-DBS). After 4 months of high intensity Voa-DBS, cognitively unimpaired, he showed major improvement in dystonia, became ambulant, but committed suicide. Brain examination confirmed the correct location of the electrodes in GPi and Voa on both sides.
authors.affiliation: Department of Neurology, Centre Hospitalia Universitaire Vaudois, Lausanne, Switzerland. joseph.ghika@chuv.hospvc.ch
authors.forename: J
authors.initials: J
authors.lastname: Ghika
authors.forename: J G
authors.initials: JG
authors.lastname: Villemure
authors.forename: J
authors.initials: J
authors.lastname: Miklossy
authors.forename: P
authors.initials: P
authors.lastname: Temperli
authors.forename: E
authors.initials: E
authors.lastname: Pralong
authors.forename: S
authors.initials: S
authors.lastname: Christen-Zaech
authors.forename: C
authors.initials: C
authors.lastname: Pollo
authors.forename: P
authors.initials: P
authors.lastname: Maeder
authors.forename: J
authors.initials: J
authors.lastname: Bogousslavsky
authors.forename: F
authors.initials: F
authors.lastname: Vingerhoets
mesh_terms: D000328:Adult; D001479:Basal Ganglia / Q000473:pathology; D004421:Dystonia / Q000473:pathology / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy*; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D013238:Stereotaxic Techniques; D013788:Thalamus / Q000502:physiology*