Juncenolide A, a new briarane from the Taiwanese Gorgonian Junceella juncea.
Fractionation of the acetone extract of Junceella juncea collected in Taiwan resulted in the isolation of a new briarane, designated juncenolide A (1). The structure of 1 was determined on the basis of 2D NMR techniques, including COSY, HSQC, HMBC, and NOESY experiments, and was also confirmed by X-ray crystallographic analysis.
Shen
Ya-Ching
YC
Institute of Marine Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung, Taiwan, Republic of China. ycshen@mail.nsysu.edu.tw
Lin
Yu-Chi
YC
Chiang
Michael Y
MY
D000818:Animals; D003063:Cnidaria / Q000737:chemistry*; D003110:Colonic Neoplasms; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020128:Inhibitory Concentration 50; D007624:KB Cells; D013058:Mass Spectrometry; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013055:Spectrophotometry, Infrared; D013624:Taiwan; D014407:Tumor Cells, Cultured / Q000187:drug effects
D004224:Diterpenes; C449757:juncenolide A