title: Dying trajectory in the last year of life: does cancer trajectory fit other diseases?
abstract: OBJECTIVE
  To examine differences in the pattern of functional decline among persons dying of cancer and other leading noncancer causes of death.
  
  
  METHODS
  Mortality followback survey of next of kin listed on death certificate.
  
  
  METHODS
  Probability sample of all deaths in the United States.
  
  
  METHODS
  Next of kin for 3,614 decedents that represented 914,335 deaths.
  
  
  METHODS
  Days of difficulty with activities of daily living and mobility in the last year of life.
  
  
  RESULTS
  Relative to other decedents, patients with cancer experienced an increased rate of functional impairment beginning as late as 5 months prior to death. For example, only 13.9% of patients with cancer had difficulty getting out of bed or a chair 1-year prior to death. This increased from 22.2% to 63.0% in the last five months of life. In contrast, decedents from other diseases had higher rates of functional impairment 1 year prior to death (approximately 35% had difficulty getting out of bed or chair) and they manifested a more gradual increase in the level of functional decline (approximately 50% had difficulty getting out of bed). Precipitous functional decline was associated with hospice involvement and dying at home.
  
  
  CONCLUSIONS
  Persons dying of cancer experienced sharp functional decline in the last months of life whereas other decedents' have a more gradual decline. The more precipitous functional decline was associated with hospice involvement and dying at home.
authors.affiliation: Department of Community Health, Center for Gerontology and Health Care Research, Brown University School of Medicine, Providence, Rhode Island, USA. Joan_Teno@brown.edu
authors.forename: J M
authors.initials: JM
authors.lastname: Teno
authors.forename: S
authors.initials: S
authors.lastname: Weitzen
authors.forename: M L
authors.initials: ML
authors.lastname: Fennell
authors.forename: V
authors.initials: V
authors.lastname: Mor
mesh_terms: D000203:Activities of Daily Living; D003625:Data Collection; D003643:Death; D003644:Death Certificates; D003920:Diabetes Mellitus / Q000401:mortality / Q000503:physiopathology; D018450:Disease Progression; D006333:Heart Failure / Q000401:mortality / Q000503:physiopathology; D017051:Hospice Care / Q000706:statistics & numerical data; D006801:Humans; D009369:Neoplasms / Q000401:mortality* / Q000503:physiopathology*; D011379:Prognosis; D029424:Pulmonary Disease, Chronic Obstructive / Q000401:mortality / Q000503:physiopathology; D020521:Stroke / Q000401:mortality / Q000503:physiopathology; D014481:United States / Q000453:epidemiology