title: Verification of IMRT dose distributions using a water beam imaging system.
abstract: A water beam imaging system (WBIS) has been developed and used to verify dose distributions for intensity modulated radiotherapy using dynamic multileaf collimator. This system consisted of a water container, a scintillator screen, a charge-coupled device camera, and a portable personal computer. The scintillation image was captured by the camera. The pixel value in this image indicated the dose value in the scintillation screen. Images of radiation fields of known spatial distributions were used to calibrate the device. The verification was performed by comparing the image acquired from the measurement with a dose distribution from the IMRT plan. Because of light scattering in the scintillator screen, the image was blurred. A correction for this was developed by recognizing that the blur function could be fitted to a multiple Gaussian. The blur function was computed using the measured image of a 10 cm x 10 cm x-ray beam and the result of the dose distribution calculated using the Monte Carlo method. Based on the blur function derived using this method, an iterative reconstruction algorithm was applied to recover the dose distribution for an IMRT plan from the measured WBIS image. The reconstructed dose distribution was compared with Monte Carlo simulation result. Reasonable agreement was obtained from the comparison. The proposed approach makes it possible to carry out a real-time comparison of the dose distribution in a transverse plane between the measurement and the reference when we do an IMRT dose verification.
authors.affiliation: Department of Radiation Oncology, Stanford University School of Medicine, California 94305-5304, USA. js_li@fccc.edu
authors.forename: J S
authors.initials: JS
authors.lastname: Li
authors.forename: A L
authors.initials: AL
authors.lastname: Boyer
authors.forename: C M
authors.initials: CM
authors.lastname: Ma
mesh_terms: D002138:Calibration; D008027:Light; D015233:Models, Statistical; D009010:Monte Carlo Method; D016011:Normal Distribution; D017785:Photons; D020266:Radiotherapy, Conformal / Q000295:instrumentation* / Q000379:methods*; D012542:Scattering, Radiation; D014867:Water; D014965:X-Rays
chemical_list: D014867:Water