title: Glial processes are glued to synapses via Ca(2+)-permeable glutamate receptors.
abstract: Bergmann glia in the cerebellum elaborately ensheathe Purkinje cell dendrites and synapses, and express high levels of Ca(2+)-permeable glutamate receptors (GluRs). Suppression of the Ca(2+) permeability by virus-mediated GluR2 transfer has revealed that GluR-mediated Ca(2+) signaling is essential to maintain both structural and functional connections between the glial cell and the glutamatergic synapses.
authors.affiliation: Dept of Anatomy, Hokkaido University School of Medicine, 060-8638, Sapporo, Japan. watamasa@med.hokudai.ac.jp
authors.forename: Masahiko
authors.initials: M
authors.lastname: Watanabe
mesh_terms: D027322:Amino Acid Transport System X-AG / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D018698:Glutamic Acid / Q000378:metabolism; D006801:Humans; D009457:Neuroglia / Q000378:metabolism* / Q000648:ultrastructure; D009473:Neuronal Plasticity / Q000502:physiology; D011689:Purkinje Cells / Q000166:cytology / Q000378:metabolism*; D018091:Receptors, AMPA / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D027322:Amino Acid Transport System X-AG; D018091:Receptors, AMPA; D018698:Glutamic Acid; D002118:Calcium