title: Perfectly monodisperse microbubbling by capillary flow focusing.
abstract: Here we report a simple microfluidics phenomenon which allows the efficient mass production of micron size gas bubbles with a perfectly monodisperse and controllable diameter. It resorts on a self-excited breakup phenomenon (which locks at a certain frequency) of a short gas microligament coflowing in a focused liquid stream. In this work, we describe the physics of the phenomenon and obtain closed expressions for the bubble diameter as a function of the liquid and gas properties, geometry, and flow parameters, from a large set of experimental results.
authors.affiliation: Escuela Superior de Ingenieros, Universidad de Sevilla, Camino de los Descubrimientos s/n, 41092 Sevilla, Spain.
authors.forename: A M
authors.initials: AM
authors.lastname: Gañán-Calvo
authors.forename: J M
authors.initials: JM
authors.lastname: Gordillo
mesh_terms: D001671:Biochemistry / Q000379:methods; D016503:Drug Delivery Systems; D005740:Gases / Q000737:chemistry*
chemical_list: D005740:Gases