title: Stereoselective formal synthesis of pseudodistomin C.
abstract: [reaction: see text] Trisubstituted benzenesulfonylmethylpiperidine 4, in which the substituents are all cis to each other, is a direct synthetic precursor of the cytotoxic marine alkaloid pseudodistomin C; it has been synthesized with total diastereoselectivities from (S)-pyroglutaminol.
authors.affiliation: Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette, France. nicole.langlois@icsn.cnrs-gif.fr
authors.forename: Nicole
authors.initials: N
authors.lastname: Langlois
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis*; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D010880:Piperidines / Q000138:chemical synthesis*; D013237:Stereoisomerism; D014561:Urochordata / Q000737:chemistry
chemical_list: D000470:Alkaloids; D000970:Antineoplastic Agents; D010880:Piperidines; C449039:pseudodistomin C