title: [Differentiated carcinoma of the thyroid in children and adolescents].
abstract: OBJECTIVE
  Evaluation of resection "à la demande" for differentiated thyroid carcinoma in young patients.
  
  
  METHODS
  From 1963 to 1996, 70 differentiated thyroid carcinomas were observed in young patients (mean age: 16 years, range: 9-19 years). Three had pulmonary metastases. Resections were 39 extra-capsular lobo-isthmectomies (56%), 11 total lobo-isthmectomies with contra lateral subtotal lobectomies (16%), and 20 total thyroïdectomies "de nécessité" (28%). Lymph node resection was unilateral in 41 cases (58%), bilateral in 23 (33%), and more extended in 5 (7%). In tracheal (n = 8), esophageal (n = 4) or bilateral inferior laryngeal nerve involvement (n = 6), the visceral extension was preserved and surgery completed with postoperative external radiotherapy. In patients with pulmonary métastases surgery was completed with I131. Two patients were lost of follow-up. The others were evaluated from 5 years to 28 years later.
  
  
  RESULTS
  There were no postoperative deaths, no laryngeal palsy except those existing before surgery. In 6 patients, resection was complicated by permanent hypoparathyroidism. In the follow-up, the death of two patients was not correlated with the thyroid carcinoma. Five patients who had a recurrence were reoperated and were alive without any sign of recurrence. All the patients were alive.
  
  
  CONCLUSIONS
  These results suggest that in children and adolescent patients, without previous irradiation, a surgical procedure "à la demande" is justified. Preservation of tracheal, esophageal or laryngeal involvement, followed by postoperative radiotherapy was associated with good results.
authors.affiliation: Service de chirurgie cervicofaciale, centre anticancéreux de Shanghai, République populaire de Chine.
authors.forename: Y
authors.initials: Y
authors.lastname: Wu
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000532:radiotherapy / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002291:Carcinoma, Papillary / Q000532:radiotherapy / Q000601:surgery*; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery; D008297:Male; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D012737:Sex Factors; D013964:Thyroid Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D013965:Thyroidectomy; D013997:Time Factors
chemical_list: D007457:Iodine Radioisotopes