title: Primary lymphoma of bilateral external auditory canals.
abstract: We report a rare case of primary lymphoma originating in the bilateral external auditory canals. A 49-year-old man presented with cauliflower-like tumors on both of his external auditory canals. Immunohistopathologic examination and immunoglobulin heavy chain gene rearrangement studies led to a diagnosis of B-cell lymphoma. He had no other systemic involvement. After chemotherapy, total gross tumor removal by surgery was achieved, and no recurrence has been detected during 1 year of follow-up. To our knowledge, this is the third case of malignant lymphoma originating in the external auditory canal to be reported in the literature, and this is the first report that includes immunohistochemical findings of fresh tissue.
authors.affiliation: Department of Otolaryngology, University Hospital, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, Oita-gun, Oita 879-5593, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Shuto
authors.forename: Tomoyo
authors.initials: T
authors.lastname: Ueyama
authors.forename: Masashi
authors.initials: M
authors.lastname: Suzuki
authors.forename: Goro
authors.initials: G
authors.lastname: Mogi
mesh_terms: D004424:Ear Canal / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D004428:Ear Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D013506:Otologic Surgical Procedures / Q000379:methods; D014057:Tomography, X-Ray Computed