title: [Role of phosphate in recurrent calcium lithiasis. A current view].
abstract: OBJECTIVE
  To analyze the biochemical impact of treatment with phosphates in patients with recurrent calcium lithiasis and hypercalciuria.
  
  
  METHODS
  20 patients were selected according to the following criteria: normal renal function, recurrent calcium nephrolithiasis, hypercalciuria, hypophosphatemia, normal calcium and low tubular phosphate reabsorption (TPR). The mean duration of treatment was 7.5 +/- 3.8 months. The pre and post-treatment phosphatemia, calciuria, phosphaturia and TPR were analyzed. The results were analyzed by the Wilcoxon statistical method.
  
  
  RESULTS
  We found a moderate but significant decrease of calciuria (326.5 +/- 52-4 to 266.4 +/- 31.7 mg/24 h), while phosphatemia (2.21 +/- 0.09 to 2.52 +/- 0.30 mg/24 h) and TPR (65.7 +/- 6.3 to 71.3 +/- 4.1) increased significantly. Overall treatment was well-tolerated and no patient abandoned treatment.
  
  
  CONCLUSIONS
  The short-term biochemical results obtained are similar to those reported in the literature. However, definitive conclusions cannot be made since treatment application is not standardized and studies that demonstrate its clinical efficacy are scanty.
authors.affiliation: Servicio de Urología, Hospital Universitario de Valme, Sevilla, España.
authors.forename: M C
authors.initials: MC
authors.lastname: Reina Ruiz
authors.forename: J M
authors.initials: JM
authors.lastname: Conde Sánchez
authors.forename: M
authors.initials: M
authors.lastname: Domínguez Domínguez
authors.forename: J
authors.initials: J
authors.lastname: Espinosa Olmedo
authors.forename: M
authors.initials: M
authors.lastname: García Pérez
mesh_terms: D002118:Calcium / Q000032:analysis*; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000737:chemistry / Q000188:drug therapy*; D008297:Male; D010710:Phosphates / Q000627:therapeutic use*; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D010710:Phosphates; D002118:Calcium