Vegetative pyoderma gangrenosum in chronic renal failure.
We report the case of a 58-year-old woman with painful recurrent erythematous lesions on both legs of 6 months' duration. The patient had been treated with haemodialysis for chronic renal failure for the previous 10 years. Physical examination revealed pea-sized erythematous nodules with sinus formation and discharge of bloody pus, which yielded neither bacterial nor fungal cells in culture. These lesions healed leaving cribriform scars, after bed rest, topical disinfection and systemic and in some areas intralesional corticosteroids. Cases of pyoderma gangrenosum are usually classified as one of four clinical variants: ulcerative, pustular, bullous and vegetative. Our case might correspond to a vegetative form in view of the development of sinuses, neutrophilic abscesses and palisading granuloma, even though no ulceration was observed.
Goto
M
M
Department of Dermatology, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, Oita-gun, Oita 879-5593, Japan. gotomizu@oita-med.ac.jp
Okamoto
O
O
Fujiwara
S
S
Yanagi
T
T
Komada
S
S
Yokoyama
S
S
Takayasu
S
S
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D017511:Pyoderma Gangrenosum / Q000188:drug therapy / Q000209:etiology*; D006435:Renal Dialysis; D013256:Steroids; D016896:Treatment Outcome; D014605:Uveitis / Q000209:etiology
D000893:Anti-Inflammatory Agents; D013256:Steroids