title: Successful explantation of a ventricular assist device following fulminant influenza type A-associated myocarditis.
abstract: We report a case of fulminant myocarditis associated with refractory ventricular fibrillation following influenza A infection. Histologic examination was consistent with myocarditis and serology confirmed the viral etiology. The patient was supported with biventricular assist devices for 20 days during which her refractory ventricular fibrillation resolved spontaneously. This is the first documented case of resolution of prolonged ventricular fibrillation while on a ventricular assist device. This case suggests those patients with fulminant viral myocarditis and refractory ventricular arrhythmias may be supported successfully with ventricular assist devices until myocardial recovery takes place.
authors.affiliation: Division of Infectious Diseases, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA. pmcgover@mail.med.upenn.edu
authors.forename: Paul C
authors.initials: PC
authors.lastname: McGovern
authors.forename: Susan
authors.initials: S
authors.lastname: Chambers
authors.forename: Emily A
authors.initials: EA
authors.lastname: Blumberg
authors.forename: Michael A
authors.initials: MA
authors.lastname: Acker
authors.forename: Suman
authors.initials: S
authors.lastname: Tiwari
authors.forename: Jeffery K
authors.initials: JK
authors.lastname: Taubenberger
authors.forename: Alysia
authors.initials: A
authors.lastname: Carboni
authors.forename: Carol
authors.initials: C
authors.lastname: Twomey
authors.forename: Evan
authors.initials: E
authors.lastname: Loh
mesh_terms: D000328:Adult; D004869:Equipment Safety; D005260:Female; D006353:Heart-Assist Devices; D006801:Humans; D009980:Influenza A virus; D007251:Influenza, Human; D009205:Myocarditis / Q000601:surgery* / Q000821:virology*; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000295:instrumentation; D014693:Ventricular Fibrillation / Q000209:etiology* / Q000601:surgery*