title: Placental site trophoblastic tumor (PSTT) in mother and child: first report of PSTT in infancy.
abstract: BACKGROUND
  To the authors' knowledge, placental site trophoblastic tumors occurring simultaneously in mother and infant have not previously been reported.
  
  
  METHODS
  The clinicopathologic features of metastatic placental site trophoblastic tumor in a mother and her 4-month-old son are described.
  
  
  RESULTS
  The disease in the infant was aggressive, and he died in multiorgan failure within 5 weeks of hospital admission. Autopsy showed widespread metastases to liver, lungs, pleura, kidney, mesentery and lymph nodes. The mother, who had a uterine tumor and lung metastases, was treated with chemotherapy and hysterectomy and has no evidence of disease 26 months post-treatment.
  
  
  CONCLUSIONS
  This report shows that placental site trophoblastic tumors can metastasize in both mother and child.
authors.affiliation: Pediatric Surgical Service, Department of Surgery, The National Hospital, Rikshospitalet, Oslo, Norway. tom.monclair@rikshospitalet.no
authors.forename: Tom
authors.initials: T
authors.lastname: Monclair
authors.forename: Vera M
authors.initials: VM
authors.lastname: Abeler
authors.forename: Janne
authors.initials: J
authors.lastname: Kaern
authors.forename: Lisa
authors.initials: L
authors.lastname: Walaas
authors.forename: Bernward
authors.initials: B
authors.lastname: Zeller
authors.forename: Carsten
authors.initials: C
authors.lastname: Hilstrøm
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007223:Infant; D008113:Liver Neoplasms / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary; D008297:Male; D011247:Pregnancy; D018245:Trophoblastic Tumor, Placental Site / Q000473:pathology / Q000556:secondary / Q000601:surgery; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery