title: The role of the ventrolateral nucleus of the thalamus in the switching of descending influences to motor activity in the rat.
abstract: Studies on rats showed that the facilitating influence of preliminary transection of the rubrospinal tract on recovery of motor activity and operant reflexes disrupted by lesioning of the red nucleus was more apparent when lesioning was chemical than when lesioning was electrolytic. This is due to the survival of cerebellothalamic fibers to the ventrolateral nucleus of the thalamus after chemical lesioning of the red nucleus with quinolinic acid. It was also shown that preliminary lesioning of the ventrolateral thalamic nucleus strongly hindered the switching of motor activity under the control of the corticospinal tract in rats subjected to section of the rubrospinal tract and lesioning of the red nucleus.
authors.affiliation: Laboratory for Central Nervous System Physiology, L. A. Orbeli Institute of Physiology, Armenian National Academy of Sciences, Erevan.
authors.forename: V V
authors.initials: VV
authors.lastname: Fanardzhyan
authors.forename: E V
authors.initials: EV
authors.lastname: Papoyan
authors.forename: V I
authors.initials: VI
authors.lastname: Pogosyan
authors.forename: O V
authors.initials: OV
authors.lastname: Gevorkyan
mesh_terms: D000818:Animals; D002529:Cerebellar Nuclei / Q000166:cytology / Q000502:physiology; D003216:Conditioning, Operant / Q000502:physiology; D005260:Female; D008297:Male; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D009498:Neurotoxins / Q000633:toxicity; D004856:Postural Balance / Q000187:drug effects / Q000502:physiology; D017378:Quinolinic Acid / Q000633:toxicity; D051381:Rats; D012012:Red Nucleus / Q000166:cytology / Q000187:drug effects / Q000502:physiology; D013116:Spinal Cord / Q000187:drug effects / Q000502:physiology; D020651:Ventral Thalamic Nuclei / Q000166:cytology / Q000187:drug effects / Q000502:physiology*
chemical_list: D009498:Neurotoxins; D017378:Quinolinic Acid