title: Biomedicine. Under pressure.
authors.affiliation: Department of Ophthalmology, University of Alberta, Edmonton, T6G 2S2 Alberta, Canada.
authors.forename: James S
authors.initials: JS
authors.lastname: Friedman
authors.forename: Michael A
authors.initials: MA
authors.lastname: Walter
mesh_terms: D000483:Alleles; D001189:Aryl Hydrocarbon Hydroxylases; D018797:Cell Cycle Proteins; D002874:Chromosome Mapping; D002924:Ciliary Body / Q000378:metabolism; D065633:Cytochrome P-450 CYP1B1; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics; D003598:Cytoskeletal Proteins; D005136:Eye Proteins / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics* / Q000502:physiology*; D005260:Female; D015870:Gene Expression; D008040:Genetic Linkage; D005902:Glaucoma, Open-Angle / Q000235:genetics*; D006023:Glycoproteins / Q000235:genetics; D006056:Golgi Apparatus / Q000737:chemistry; D006801:Humans; D008297:Male; D026901:Membrane Transport Proteins; D009154:Mutation; D020125:Mutation, Missense; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics* / Q000502:physiology*; D010375:Pedigree; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D014129:Trabecular Meshwork / Q000378:metabolism; D035582:Transcription Factor TFIIIA; D000099179:Myocilin
chemical_list: D001189:Aryl Hydrocarbon Hydroxylases; D018797:Cell Cycle Proteins; D065633:Cytochrome P-450 CYP1B1; D003577:Cytochrome P-450 Enzyme System; D003598:Cytoskeletal Proteins; D005136:Eye Proteins; D006023:Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D012333:RNA, Messenger; D035582:Transcription Factor TFIIIA; D000099179:Myocilin; C409460:OPTN protein, human; C585496:CYP1B1 protein, human