Ultrastructural differentiation of cardiomyocytes of the zebrafish during the 8-26-somite stages.
We report cellular hypertrophy, mitochondrial proliferation and differentiation, myofibrillogenesis, and junctional maturation in cardiac progenitor cells between the 8 and 26-somite stages of the zebrafish, Danio rerio. However, coordinated contraction in embryonic cardiomyocytes did not occur until 26-somite stage when 'developed' intercalated discs, rooted sarcomeres, and a well-established sarcoplasmic reticulum had differentiated.
Wanga
J
J
Department of Biology, Howard University, Washington, DC, USA.
Eckberg
W R
WR
Anderson
W A
WA
D000818:Animals; D002454:Cell Differentiation; D048429:Cell Size / Q000502:physiology; D004625:Embryo, Nonmammalian / Q000166:cytology* / Q000502:physiology; D005314:Embryonic and Fetal Development; D005260:Female; D006321:Heart / Q000196:embryology* / Q000502:physiology; D007365:Intercellular Junctions / Q000502:physiology / Q000648:ultrastructure; D008297:Male; D008929:Mitochondria, Heart / Q000502:physiology / Q000648:ultrastructure; D009200:Myocardial Contraction / Q000502:physiology; D009206:Myocardium / Q000648:ultrastructure*; D012518:Sarcomeres / Q000502:physiology / Q000648:ultrastructure; D012519:Sarcoplasmic Reticulum / Q000502:physiology / Q000648:ultrastructure; D019170:Somites; D015027:Zebrafish / Q000196:embryology*