title: [Pulmonary mucormycosis caused by Cunninghamella bertholletiae in a non-immunocompromised woman].
abstract: A 74-year-old woman was admitted for further examination because of an abnormal nodular shadow and thickening of the bronchovascular bundle in the left upper lobe on chest radiography and CT. The findings from a transbronchial biopsy specimen were not conclusive. A thoracoscopic lung biopsy specimen revealed a fungal infection, and partial resection of S1 + 2 of the left upper lobe was carried out. In the dilated bronchus, mucus of high viscosity was seen. Lymphocytes and plasma cells had infiltrated into the bronchioles and alveoli. Fungus was cultured from the mucus, and the morphological characteristics showed Cunninghamella bertholletiae. Pulmonary mucormycosis caused by C. bertholletiae in a non-immunocompromised person is very rare. Furthermore, this patient also had a wheeze, eosinophilia, elevation of the serum IgE level, and was positive for specific IgE to Mucor. We therefore consider that this case was an incomplete type of allergic bronchopulmonary fungusis (ABPF).
authors.affiliation: Department of Respiratory Medicine, Fukuroi Municipal Hospital, 2515-1 Kuno, Fukuroi, Shizuoka 437-0061, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Sato
authors.forename: H
authors.initials: H
authors.lastname: Gemma
authors.forename: T
authors.initials: T
authors.lastname: Sano
authors.forename: T
authors.initials: T
authors.lastname: Ono
authors.forename: E
authors.initials: E
authors.lastname: Atsumi
authors.forename: I
authors.initials: I
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Chida
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D000368:Aged; D020093:Cunninghamella; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008172:Lung Diseases, Fungal / Q000382:microbiology* / Q000473:pathology; D009091:Mucormycosis / Q000382:microbiology* / Q000473:pathology