Relationship between nuchal translucency at 11-14 weeks and nuchal fold at 20-24 weeks of gestation.
OBJECTIVE
To examine the relationship between the measurement of nuchal translucency in the first trimester and nuchal fold in the second trimester in normal pregnancy.


METHODS
This was a prospective study of 592 singleton pregnancies. Fetal nuchal translucency was measured at 11-14 weeks of gestation and nuchal fold at 20-24 weeks of gestation. Linear regression models were used to assess the relationship between nuchal translucency and nuchal fold after adjustment for gestational age.


RESULTS
There was no significant association between nuchal translucency and nuchal fold thickness.


CONCLUSIONS
It is possible that measurement of nuchal translucency and nuchal fold may provide an independent contribution in screening for trisomy 21.
Salomon
L J
LJ
Service de Gynécologie-Obstétrique, Centre Hospitalier Intercommunal de Poissy-St Germain, 10 rue du Champ Gaillard, 78300 Poissy, France.
Bernard
J P
JP
Taupin
P
P
Benard
C
C
Ville
Y
Y
D004314:Down Syndrome / Q000000981:diagnostic imaging*; D005260:Female; D005865:Gestational Age; D006801:Humans; D016014:Linear Models; D009333:Neck / Q000196:embryology*; D011247:Pregnancy; D011446:Prospective Studies; D016216:Ultrasonography, Prenatal