[Early use of Chinese drug rhodiola compound for patients with post-trauma and inflammation in prevention of ALI/ARDS].
OBJECTIVE
To evaluate the effects of the Chinese drug rhodiola on the preventive treatment of acute lung injury (ALI) caused by post-traumatic/inflammatory and thoracic-cardiovascular operations.


METHODS
104 patients who coincide with their diagnosis and standard scale were divided randomly in to single number groups A(1), B(1), C(1) and D(1) (early preventive treatment group EG) and double number groups A(2), B(2), C(2) and D(2) (control group CG). The treatment of primary disease both in EG and CG was similar, but in EG four grams of rhodiola compound (RCO) were used every day for a period of 3-15 days since admission and 5-7 days after operation. The indicators related to ALI in each groups were measured.


RESULTS
PaO(2), AaDO(2) and hemorheology were significant in EG than in CG (P < 0.05) or (P < 0.01). The complication rate of ARDS was decreased about of 50.0% in EG than in CG.


CONCLUSIONS
Early use of RCO may protect against major risk factors of ALI/ARDS caused by massive trauma/infection and thoracic-cardio-operations.
Zhang
S
S
Department of Thoracic Cardiovasc Surgery, General Hospital of Lanzhou Unit, People's Liberation Army, Lanzhou 730050.
Gao
W
W
Xu
K
K
Guo
Y
Y
Lin
S
S
Xue
X
X
Lu
G
G
Li
N
N
Liu
H
H
Liu
W
W
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011446:Prospective Studies; D012128:Respiratory Distress Syndrome / Q000188:drug therapy / Q000517:prevention & control*; D029771:Rhodiola
D004365:Drugs, Chinese Herbal