title: Frequency of isolation of Staphylococcus lugdunensis in consecutive urine cultures and relationship to urinary tract infection.
abstract: Recent reports associate Staphylococcus lugdunensis with severe infection in humans. The frequency of this microorganism in urine cultures is unknown. Five hundred isolates of coagulase-negative staphylococci (CoNS) were recovered from 4,652 consecutive urine specimens submitted for culture to the Mayo Clinic Microbiology Laboratory. Thirty-one (6%) of 500 isolates of CoNS were identified as S. lugdunensis. In no case was S. lugdunensis isolated in pure culture; 29 (94%) of 31 S. lugdunensis isolates were part of mixed nonpathogenic flora. Medical records were reviewed for 30 of the 31 patients from whom these 31 isolates were isolated. Twenty-one (70%) of the 30 evaluable patients were not treated with antibiotics; the remaining 9 (30%) of 30 patients were treated with antibiotics that may be effective against S. lugdunensis. S. lugdunensis may be an unrecognized yet infrequent cause of urinary tract infection.
authors.affiliation: Mayo Medical School, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
authors.forename: D T
authors.initials: DT
authors.lastname: Haile
authors.forename: J
authors.initials: J
authors.lastname: Hughes
authors.forename: E
authors.initials: E
authors.lastname: Vetter
authors.forename: P
authors.initials: P
authors.lastname: Kohner
authors.forename: R
authors.initials: R
authors.lastname: Snyder
authors.forename: R
authors.initials: R
authors.lastname: Patel
authors.forename: F R
authors.initials: FR
authors.lastname: Cockerill
mesh_terms: D000368:Aged; D001431:Bacteriological Techniques; D003030:Coagulase / Q000378:metabolism; D003470:Culture Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology*; D013210:Staphylococcus / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity*; D014552:Urinary Tract Infections / Q000382:microbiology*; D014556:Urine / Q000382:microbiology*
chemical_list: D003030:Coagulase; D003470:Culture Media