New-onset ichthyosis and diabetes in a 14-year-old.
Diabetes has not been linked to acquired ichthyosis or ichthyosis vulgaris. We report a newly diagnosed diabetic 14-year-old girl with bilateral tibial and sacral ichthyosiform plaques and a hemoglobin A1c of 20.1%. The patient had no personal or family history of atopy or ichthyosis and lacked keratosis pilaris or hyperlinear palms. A biopsy specimen of an ichthyosiform plaque showed compact lamellar orthohyperkeratosis and hypogranulosis, histopathology consistent with either ichthyosis vulgaris or acquired ichthyosis. We speculate that our patient's new-onset diabetes induced acquired ichthyosis.
Scheinfeld
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Department of Dermatology, Albert Einstein College of Medicine, Bronx, New York, USA. scheinfeld@rcn.com
Libkind
M
M
Freilich
S
S
D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D005260:Female; D006801:Humans; D007057:Ichthyosis / Q000150:complications* / Q000473:pathology; D016112:Ichthyosis Vulgaris / Q000150:complications / Q000473:pathology; D012867:Skin / Q000473:pathology