title: Role of laparoscopy in the treatment of endometriosis-associated infertility.
abstract: Endometriosis is assumed to be one of the causative factors of infertility, although the mechanism remains to be elucidated. Mechanical factors distorting the pelvic anatomy and/or changes in the biochemical and cellular environment in the peritoneal cavity are possible contributing factors impairing fertility. Laparoscopy is a widely used diagnostic and therapeutic means of treating endometriosis-associated infertility. However, pregnancy outcome after laparoscopy varies depending on preexisting tubal adhesions and endometriosis. Without tubal adhesions, the pregnancy rate is essentially the same irrespective of the presence or stages of endoemetriosis. Minimal/mild endometriosis benefited the most from laparoscopic manipulation when tubal adhesions were present. On the other hand, IVF-ET outcome of patients who previously underwent laparoscopy was not influenced by preexisiting tubal adhesions and endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Tokyo, Japan. yutakaos-tky@umin.ac.jp
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Osuga
authors.forename: Kaori
authors.initials: K
authors.lastname: Koga
authors.forename: Osamu
authors.initials: O
authors.lastname: Tsutsumi
authors.forename: Tetsu
authors.initials: T
authors.lastname: Yano
authors.forename: Masonori
authors.initials: M
authors.lastname: Maruyama
authors.forename: Koji
authors.initials: K
authors.lastname: Kugu
authors.forename: Mikio
authors.initials: M
authors.lastname: Momoeda
authors.forename: Yuji
authors.initials: Y
authors.lastname: Taketani
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*; D010535:Laparoscopy / Q000379:methods*; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D011247:Pregnancy / Q000706:statistics & numerical data*; D011256:Pregnancy Outcome; D012680:Sensitivity and Specificity; D016896:Treatment Outcome