[Unexpected high plasma level of drugs. Blocked transporter can be the cause].
Fromm
M F
MF
Dr. Margarete-Fischer-Bosch-Institut für Klinische Pharmakologie, Stuttgart. martin.fromm@ikp-stuttgart.de
D000889:Anti-Arrhythmia Agents / Q000097:blood / Q000378:metabolism; D001682:Biological Availability; D001693:Biological Transport, Active; D001812:Blood-Brain Barrier; D001814:Blood-Testis Barrier; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004077:Digoxin / Q000097:blood / Q000378:metabolism; D004347:Drug Interactions; D005260:Female; D006023:Glycoproteins / Q000378:metabolism; D006801:Humans; D008297:Male; D006899:Mixed Function Oxygenases / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000097:blood* / Q000378:metabolism*; D011802:Quinidine / Q000378:metabolism
D000889:Anti-Arrhythmia Agents; D006023:Glycoproteins; D004364:Pharmaceutical Preparations; D004077:Digoxin; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; D011802:Quinidine