Preparation and antimalarial activities of "trioxaquines", new modular molecules with a trioxane skeleton linked to a 4-aminoquinoline.
Dechy-Cabaret
O
O
Laboratoire de Chimie de Coordination du CNRS 205 route de Narbonne, 31077 Toulouse, France.
Benoit-Vical
F
F
Robert
A
A
Meunier
B
B
D000634:Aminoquinolines / Q000138:chemical synthesis / Q000494:pharmacology*; D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis* / Q000494:pharmacology*; D002738:Chloroquine / Q000494:pharmacology; D002951:Citrates / Q000138:chemical synthesis / Q000494:pharmacology*; D004351:Drug Resistance; D066298:In Vitro Techniques; D010963:Plasmodium falciparum / Q000187:drug effects*; D012717:Sesquiterpenes / Q000138:chemical synthesis / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000634:Aminoquinolines; D000962:Antimalarials; D002951:Citrates; C452564:ODC188; C452565:ODC218; D012717:Sesquiterpenes; D002738:Chloroquine; C001920:4-aminoquinoline