title: [Morphofunctional changes in the pineal gland during adaptation to hypothermia].
abstract: The influence of hypothermal stress (+4 degrees during 3 h) on the ways of serotonin metabolism in pineal gland and its structure has been studied in dynamics on adult male Wistar rats. It has been revealed that melatonin-producing epiphyseal function suffers from phase changes in dynamics of adaptation--significant rising during 15 min. after beginning of the experiment, rehabilitation up to normal--in 30 min, and fast suppressing--in 3 hrs. Suppressing of the functional pineal activity is not due to switched serotonin metabolism with melatonin and new indoles release, but to a partial pinealocytes breaking from their active function.
authors.forename: L A
authors.initials: LA
authors.lastname: Bondarenko
authors.forename: G I
authors.initials: GI
authors.lastname: Gubina-Vakulik
mesh_terms: D008735:5-Methoxytryptamine / Q000378:metabolism; D000222:Adaptation, Physiological; D000818:Animals; D003080:Cold Temperature; D005470:Fluorometry; D006897:Hydroxyindoleacetic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D008297:Male; D008550:Melatonin / Q000378:metabolism; D010870:Pineal Gland / Q000166:cytology* / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000031:analogs & derivatives* / Q000378:metabolism
chemical_list: D012701:Serotonin; C001736:5-methoxyindoleacetic acid; D008735:5-Methoxytryptamine; D006897:Hydroxyindoleacetic Acid; D008550:Melatonin; C006389:N-acetylserotonin