[The prognostic meaning of the selection parameters amniotic fluids samples and frequency occurrence respiratory distress newborn].
Prenatal diagnosis of amniotic fluid enables the evaluation of fetal lungs maturity. The aim of the study is to evaluate prognostic significance of measurement of concentration of lamellar body count (LC) in comparison with other laboratory investigations for prenatal fetal lung maturity evaluation. The study was carried out on 60 amniotic fluid collections obtained by amniocentesis of pregnant women, hospitalized in Polish Mother's Health Centre between August 1998-January 2000. Following tests were performed: phosphatydyloglicerol concentration (PG), concentration of lamellar body (CLC), optical density-reading absorbance in wave length 400, 570, 650 nm. Test PG showed 70% specificity and 100% sensitivity, LC 70% specificity; 100% sensitivity. PG and LC showed good correlation for the assessment of fetal lung maturity. The study involved small number of patients pointed out the necessity of continuation quantitative investigation of LC to confirm diagnostics utility for the assessment of fetal lung maturity.
Swiatkowska
E
E
Instytut Centrum Zdrowia Matki Polki Zakład Diagnostyki Laboratoryjnej ul. Rzgowska 281/289, 338-338 Łódź.
Wilczyński
J
J
Sobczak
M
M
Sałacińska
B
B
D000328:Adult; D000653:Amniotic Fluid / Q000378:metabolism*; D015415:Biomarkers / Q000032:analysis; D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology* / Q000378:metabolism*; D010715:Phosphatidylglycerols / Q000378:metabolism; D011237:Predictive Value of Tests; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011379:Prognosis; D012127:Respiratory Distress Syndrome, Newborn / Q000175:diagnosis* / Q000378:metabolism*; D012680:Sensitivity and Specificity
D015415:Biomarkers; D010715:Phosphatidylglycerols