title: Rapid efficacy of highly active antiretroviral therapy in a case of HIV myelitis.
abstract: An HIV-seropositive patient with severe immunodepression was diagnosed as having HIV myelitis. Plasma and cerebrospinal fluid (CSF) HIV-RNA PCR were, respectively, 4.11 and 5.19log(10). After 1 month of treatment with highly active antiretroviral therapy (HAART), there was clinical recovery and both plasma and CSF HIV viral load had decreased considerably. This dramatic improvement was associated with a high concentration of antiviral drugs in the CSF, suggestive of the direct efficacy of HAART on HIV myelitis.
authors.affiliation: Service de Medicine Interne, Ho^pital Saint-Louis, Lavande 6, 1, avenue Claude Vellfaux, F-75475 Cedex 10, Paris, France
authors.forename: L
authors.initials: L
authors.lastname: Michou
authors.forename: C
authors.initials: C
authors.lastname: Sauve
authors.forename: C
authors.initials: C
authors.lastname: Sereni
authors.forename: C
authors.initials: C
authors.lastname: Lamotte
authors.forename: A
authors.initials: A
authors.lastname: Maillard
authors.forename: D
authors.initials: D
authors.lastname: Sereni