Adjunctive antipsychotic treatment is necessary for adolescents with psychotic mania.
Adolescents with acute psychotic mania were treated with lithium and adjunctive haloperidol as part of a lithium efficacy study. If the psychosis completely resolved, haloperidol was discontinued after 1 week of therapeutic lithium levels. Our first five subjects experienced a rapid exacerbation of symptoms, which responded to restarting haloperidol. A longer duration of adjunctive antipsychotic treatment is necessary in adolescents with bipolar psychosis.
Kafantaris
V
V
Department of Psychiatry, Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, New York, USA. kafantar@lij.edu
Dicker
R
R
Coletti
D J
DJ
Kane
J M
JM
D000208:Acute Disease; D000293:Adolescent; D000367:Age Factors; D001714:Bipolar Disorder / Q000150:complications* / Q000188:drug therapy*; D002648:Child; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008094:Lithium / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D011581:Psychological Tests; D011618:Psychotic Disorders / Q000150:complications* / Q000188:drug therapy*; D012720:Severity of Illness Index; D013997:Time Factors
D008094:Lithium; D006220:Haloperidol