Perspectives-- Focus on statins: lipid-lowering mechanisms and beyond.
Recent large-scale clinical trials have confirmed that statin-induced lipid modification can significantly reduce cardiovascular morbidity and mortality. Statins are now the drugs of choice in lipid management but fail to meet the criteria for an ideal therapy in several respects. Therefore, the search continues for lipid modifying treatments that meet even higher standards. Lipid-lowering drugs currently in development may meet these more exacting standards and together with complementary methods could ultimately form ideal combination therapy. (c) 2001 by CHF, Inc.
Auer
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IInd Med. Department with Cardiology and Intensive Care, General Hospital, Wels, Austria.
Berent
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Eber
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