Recent advances in pharmacokinetic applications of capillary electrophoresis.
This article reviews recent capillary electrophoresis (CE)-based assays which were published for pharmacokinetic studies. Both the advantages and disadvantages of these CE-based assays are discussed based on their feasibility and the significance towards the better understanding of pharmacokinetics. In addition, as a future outlook, novel assays such as immunoaffinity CE and chip-based CE for analyzing drugs in biological fluids are summarized in view of their potential for pharmacokinetic applications.
Sung
W C
WC
Department of Chemistry, National Cheng Kung University, Tainan, Taiwan.
Chen
S H
SH
D004586:Electrophoresis / Q000379:methods*; D006801:Humans; D010599:Pharmacokinetics