MutS2 family protein from Pyrococcus furiosus.
MutS2 protein of Pyrococcus furiosus has been cloned and over-expressed. Initial characterization reveals that PfuMutS2 possesses a thermostable ATPase activity and a thermostable, nonspecific DNA binding activity. However, PfuMutS2 does not have any detectable mismatch-specific DNA binding activity. It is the first in vitro characterization of an MutS2 family protein.
Vijayvargia
Ravi
R
National Centre for Cell Science, Pune University Campus, Ganeshkhind, Pune 411007, India.
Biswas
Indranil
I
D000251:Adenosine Triphosphatases / Q000235:genetics / Q000378:metabolism; D000595:Amino Acid Sequence; D019843:Archaeal Proteins / Q000235:genetics* / Q000378:metabolism*; D020137:Base Pair Mismatch; D003001:Cloning, Molecular; D004260:DNA Repair; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D004795:Enzyme Stability; D004926:Escherichia coli / Q000235:genetics; D015870:Gene Expression; D019766:Genes, Archaeal; D008969:Molecular Sequence Data; D010641:Phenotype; D020027:Pyrococcus furiosus / Q000235:genetics* / Q000378:metabolism*; D017386:Sequence Homology, Amino Acid; D013696:Temperature
D019843:Archaeal Proteins; D004268:DNA-Binding Proteins; D000251:Adenosine Triphosphatases