title: Stomal recurrence after total laryngectomy for squamous cell carcinoma of the larynx.
abstract: OBJECTIVE
  Stomal recurrence after total laryngectomy is one of the most serious issues in the management of laryngeal carcinoma. The management of stomal recurrence, including chemotherapy, radiotherapy, and surgery, has been reported as unsatisfactory.
  
  
  METHODS
  From 1985 to 1995, 69 patients underwent total laryngectomy for the treatment of laryngeal cancer at the University of Tokyo Hospital. To identify the risk factors for stomal recurrence, we analyzed these patients according to various clinicopathological factors.
  
  
  RESULTS
  Stomal recurrence developed in 6 of 69 patients who underwent total laryngectomy for laryngeal carcinoma. Statistical analysis reveals that primary site, preoperative tracheotomy, and paratracheal lymph node metastasis are significant risk factors for stomal recurrence.
  
  
  CONCLUSIONS
  Intensive follow-up should be performed for patients with glottic carcinoma who had preoperative tracheotomy, paratracheal lymph node metastasis, or both to detect stomal recurrence at an early stage.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Japan. yimauchi-tky@umin.ac.jp
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Imauchi
authors.forename: Ken
authors.initials: K
authors.lastname: Ito
authors.forename: Esao
authors.initials: E
authors.lastname: Takasago
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Nibu
authors.forename: Masashi
authors.initials: M
authors.lastname: Sugasawa
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ichimura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D009367:Neoplasm Staging; D011184:Postoperative Period; D011300:Preoperative Care; D012307:Risk Factors; D016879:Salvage Therapy; D014134:Tracheal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000556:secondary; D014140:Tracheotomy