[The treatment of colorectal liver metastases: good 5 year survival chance after partial liver resection at the Rotterdam University Hospital, 1984/1999].
OBJECTIVE
To evaluate the results of partial liver resection in patients with liver metastases.


METHODS
Retrospective.


METHODS
All of the patients who underwent a partial liver resection at the Rotterdam University Hospital during the period June 1984-August 1999 due to one or more metastases of a colorectal carcinoma were traced in the computerised hospital archive. Data concerning the primary tumour, the diagnostics carried out, the liver resection carried out and the clinical outcome after the operation were analysed using the statistical software SPSS. The actuarial survival was determined according to the Kaplan-Meier method.


RESULTS
In total 163 patients underwent an operation: 108 men and 55 women, with a mean age of 58 years (range: 32-77). Postoperative morbidity occurred in 34 patients (21%), mostly infections and gall leakage. During the hospital admission 10 patients died (6%). In the follow-up period, mean 30.2 months (median: 23.8) there was a recurrence of colorectal carcinoma in 82 of the patients (50%). The actuarial 5-year survival chance was 37%. The only statistically significant unfavourable prognosis factor for survival, was a larger tumour volume in the liver at the time of the hepatectomy.
Vlot
J
J
Afd. Algemene Heelkunde, Erasmus Medisch Centrum, Postbus 2040, 3000 CA Rotterdam.
Kazemier
G
G
Heijsterkamp
J
J
Tilanus
H W
HW
van der Sijp
J R M
JR
Ijzermans
J N M
JN
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications / Q000401:mortality; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome