title: Synthesis of the liposidomycin diazepanone nucleoside.
abstract: [structure: see text] The synthesis of the liposidomycin degradation product 4 from D-glucose establishes its stereochemistry as 5'S,6'S and, by incorporation of the earlier diazepanone relative stereochemical assignment, establishes the absolute stereochemistry of the liposidomycins 1 and 2 as 5'S,6'S,2'''S,3'''S.
authors.affiliation: Department of Chemistry & Chemical Biology, Rutgers The State University of New Jersey, Piscataway, New Jersey 08854-8087, USA.
authors.forename: Spencer
authors.initials: S
authors.lastname: Knapp
authors.forename: Gregori J
authors.initials: GJ
authors.lastname: Morriello
authors.forename: George A
authors.initials: GA
authors.lastname: Doss
mesh_terms: D001381:Azepines / Q000138:chemical synthesis*; D003500:Cyclization; D004791:Enzyme Inhibitors / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010458:Peptidyl Transferases / Q000037:antagonists & inhibitors*; D014498:Uracil / Q000031:analogs & derivatives / Q000138:chemical synthesis*
chemical_list: C451485:6'-(5-carboxy-1,4-dimethyl-3-oxo-2H,3H-1,4-diazepin-2-yl)uracil; D001381:Azepines; D004791:Enzyme Inhibitors; D014498:Uracil; D010458:Peptidyl Transferases