title: Acute phase proteins, body temperature and urinary melatonin under the influence of bright and dim light intensities during the daytime.
abstract: Concentrations of five acute phase proteins: C-reactive protein (CRP), alpha 1-antichymotrypsin (ACT), transferin (Tf), alpha 2-macroglobulin (alpha 2-M) and haptoglobin (Hp) as well as glycosylation profiles of alpha 1-antichymotrypsin (ACT) were studied in sera samples with 7 healthy volunteers under the influence of two different light intensities during the daytime dim (100 lx) and bright (3000 lx) light. Concentration of transferin (negative proteins) under the influence of bright light during the daytime decreased significantly. Other proteins have the tendency to increase (positive proteins) under the influence of daytime bright light. The microheterogeneity of ACT did not change under the influence of different light intensities. Melatonin and rectal temperature were also measured simultaneously. Rectal temperature decreased to be lower during the first half of the night and urinary melatonin secretion rate increased to be higher during the night when the subjects spent time under the bright light during the day. Thus, it is concluded that the diurnal bright light exposure may activate some parameters of acute phase proteins, increase nocturnal melatonin secretion and accelerate a fall of rectal temperature during first half period of night sleep.
authors.affiliation: Department of Environmental Health, Nara Women's University. dkanikowska@hotmail.com
authors.forename: D
authors.initials: D
authors.lastname: Kanikowska
authors.forename: Y
authors.initials: Y
authors.lastname: Hirata
authors.forename: K
authors.initials: K
authors.lastname: Hyun
authors.forename: H
authors.initials: H
authors.lastname: Tokura
mesh_terms: D000209:Acute-Phase Proteins / Q000032:analysis*; D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D001831:Body Temperature; D002940:Circadian Rhythm; D005260:Female; D006801:Humans; D008027:Light; D008550:Melatonin / Q000652:urine*
chemical_list: D000209:Acute-Phase Proteins; D000975:Antioxidants; D008550:Melatonin