title: [A 35-year-old man with gynaecomastia as the first symptom of hyperthyroidism].
abstract: A 35-year-old man suffered painful bilateral gynaecomastia for 2 months due to serious Graves' hyperthyroidism. During treatment with propylthiouracil and levothyroxine, the plasma concentrations of thyroid hormone, sex hormones and sex hormone-binding globulin normalised and the gynaecomastia disappeared. Gynaecomastia occurs in 30 to 40% of men diagnosed with Graves' hyperthyroidism. However, gynaecomastia as a presenting symptom of this autoimmune disease is uncommon.
authors.affiliation: Katholieke Universiteit Leuven, Universitair Ziekenhuis Gasthuisberg, Kliniek en Laboratorium voor Experimentele Geneeskunde en Endocrinologie, Herestraat 49, 3000 Leuven, België.
authors.forename: A
authors.initials: A
authors.lastname: Mullens
authors.forename: A
authors.initials: A
authors.lastname: van den Bruel
authors.forename: D
authors.initials: D
authors.lastname: Vanderschueren
mesh_terms: D000328:Adult; D012739:Gonadal Steroid Hormones / Q000097:blood; D006111:Graves Disease / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006177:Gynecomastia / Q000209:etiology*; D006801:Humans; D008297:Male; D012738:Sex Hormone-Binding Globulin / Q000032:analysis; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D012739:Gonadal Steroid Hormones; D012738:Sex Hormone-Binding Globulin; D013963:Thyroid Hormones