Some problems in the detection of strong mutagen MX formed by chlorinating the aromatic acids and phenolic compounds.
Ten compounds with aromatic acid and phenolic structure were chlorinated at laboratory conditions and MX analysis by GC/MS at scan mode. None of these compounds produced MX, which is contrary to the results of other researchers. The whole procedure was investigated and it was found that the results obtained at scan mode was more reliable than at SIM mode because of the possible interference. The structural characteristic of the precursors of MX is proposed.
Junhe
Lu
L
State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, People's Republic of China.
Huixia
Zou
Z
Chengyong
Yang
Y
Zirui
Yu
Y
Jinqi
Zhang
Z
D024322:Amino Acids, Aromatic / Q000737:chemistry; D004784:Environmental Monitoring / Q000379:methods*; D005663:Furans / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D009153:Mutagens / Q000032:analysis*; D010636:Phenols / Q000737:chemistry; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014874:Water Pollutants, Chemical / Q000032:analysis*
D024322:Amino Acids, Aromatic; D005663:Furans; D009153:Mutagens; D010636:Phenols; D014874:Water Pollutants, Chemical; C054121:3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone