title: Malignant transformation of fibrous dysplasia into chondroblastic osteosarcoma.
abstract: A case of malignant transformation of polyostotic fibrous dysplasia into maxillary chondroblastic osteosarcoma is presented. The clinical, radiographic, CT, MR imaging features and pathological findings of polyostotic fibrous dysplasia and its malignant transformation are described. Malignant transformation of fibrous dysplasia is rare and has not previously been described in the English literature in this location in McCune-Albright syndrome and in the absence of radiation treatment.
authors.affiliation: Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, 401 N 12th Street, Main Hospital, RM 3-417, Richmond, VA 23298-0615, USA. skaushi@hsc.vcu.edu
authors.forename: Shaifali
authors.initials: S
authors.lastname: Kaushik
authors.forename: Wendy R K
authors.initials: WR
authors.lastname: Smoker
authors.forename: William J
authors.initials: WJ
authors.lastname: Frable
mesh_terms: D000293:Adolescent; D002804:Chondroblastoma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005359:Fibrous Dysplasia, Polyostotic / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008441:Maxillary Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D012516:Osteosarcoma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D014057:Tomography, X-Ray Computed