In vitro and in silico analysis of the predicted human MOB gene encoding a phylogenetically conserved transmembrane protein.
A novel evolutionary conserved human MOB gene of seven exons is predicted on the chromosome 10. MOB is supposed to express predominately in brain. At least three types of MOB transcripts are proposed. A protein encoded by MOB is five-pass transmembrane molecule.
Vladychenskaya
I P
IP
Department of Human Molecular Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Kurchatov sq., 2, 123182, Moscow, Russia. irinavl@img.ras.ru
Dergunova
L V
LV
Limborska
S A
SA
D000595:Amino Acid Sequence; D000818:Animals; D015152:Blotting, Northern; D002874:Chromosome Mapping; D002879:Chromosomes, Human, Pair 10 / Q000235:genetics*; D003001:Cloning, Molecular; D017124:Conserved Sequence / Q000235:genetics; D020451:Contig Mapping; D018076:DNA, Complementary; D005091:Exons / Q000235:genetics; D006801:Humans; D066298:In Vitro Techniques; D008526:Medulla Oblongata / Q000502:physiology*; D008565:Membrane Proteins / Q000737:chemistry / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins; D010363:Pattern Recognition, Automated; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017855:Transferases (Other Substituted Phosphate Groups)
D018076:DNA, Complementary; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; C455440:SGMS1 protein, human; D017855:Transferases (Other Substituted Phosphate Groups)