Virulence factors of clinical isolates of Aeromonas caviae.
The mechanism of pathogenicity of 13 Aeromonas caviae strains isolated from fecal specimens of children with diarrhea was examined. Isolates possessed several virulence agents. Six of 13 isolates produced cholera-like toxin, all strains exhibited adhesive ability and secreted catecholate siderophores. Six isolates were able to grow in heat-inactivated serum. Production of hemolysins was not detected. The isolates had relatively high values of LD50 in a mouse model, which suggests that there is no linkage between pathogenicity to mice and the diarrheagenic ability of the isolates.
Mokracka
J
J
Department of Microbiology, Institute of Experimental Biology, A. Mickiewicz University, 617 01 Poznań, Poland.
Krzymińska
S
S
Szczuka
E
E
D000333:Aeromonas / Q000254:growth & development / Q000302:isolation & purification / Q000472:pathogenicity*; D000818:Animals; D001422:Bacterial Adhesion; D001427:Bacterial Toxins / Q000096:biosynthesis / Q000276:immunology; D002648:Child; D002772:Cholera Toxin / Q000276:immunology; D003470:Culture Media; D003967:Diarrhea / Q000382:microbiology*; D004195:Disease Models, Animal; D005243:Feces / Q000382:microbiology; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006801:Humans; D007583:Jejunum / Q000382:microbiology; D007928:Lethal Dose 50; D051379:Mice; D011817:Rabbits; D017262:Siderophores; D014774:Virulence
D001427:Bacterial Toxins; D003470:Culture Media; D017262:Siderophores; D002772:Cholera Toxin