title: Efficient synthesis of 3-furanosyl-6'-furanosylphosphinate through a tandem sequential radical process.
abstract: The sodium salt of hypophosphorous acid is shown to act as a double radical precursor in a double, sequential radical addition on 3-exo-methylenefuranose derivative 14 and 4-ethylenefuranose 10 to furnish phosphinates 18d in good overall yields. Unambiguous structural assignment establishes the high diastereoselection of the process.
authors.affiliation: Laboratoire des Fonctions Azotées et Oxygénées Complexes, UMR 6014 CNRS, Université de Rouen, IRCOF, Rue Tesnière, F-76821 Mont Saint Aignan, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Dubert
authors.forename: Arnaud
authors.initials: A
authors.lastname: Gautier
authors.forename: Eric
authors.initials: E
authors.lastname: Condamine
authors.forename: Serge R
authors.initials: SR
authors.lastname: Piettre