title: Cellular signalling pathways: new targets in leukaemia therapy.
authors.affiliation: Department of Hematology/Oncology, The University of Illinois at Chicago, IL, USA.
authors.forename: Farhad
authors.initials: F
authors.lastname: Ravandi
authors.forename: Moshe
authors.initials: M
authors.lastname: Talpaz
authors.forename: Hagop
authors.initials: H
authors.lastname: Kantarjian
authors.forename: Zeev
authors.initials: Z
authors.lastname: Estrov
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D002460:Cell Line; D016207:Cytokines / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005786:Gene Expression Regulation; D006801:Humans; D007378:Interleukins / Q000276:immunology / Q000378:metabolism; D053613:Janus Kinase 1; D007938:Leukemia / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D010766:Phosphorylation; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D020794:Receptor Protein-Tyrosine Kinases / Q000187:drug effects / Q000378:metabolism; D018121:Receptors, Cytokine / Q000378:metabolism*; D050794:STAT1 Transcription Factor; D015398:Signal Transduction / Q000187:drug effects*; D015534:Trans-Activators / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism
chemical_list: D000911:Antibodies, Monoclonal; D016207:Cytokines; D004268:DNA-Binding Proteins; D004791:Enzyme Inhibitors; D007378:Interleukins; D018121:Receptors, Cytokine; D050794:STAT1 Transcription Factor; C494079:STAT1 protein, human; D015534:Trans-Activators; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases; C507904:JAK1 protein, human; D053613:Janus Kinase 1