title: Interlobar lymph node metastases according to primary tumor location in lung cancer.
abstract: Interlobar lymph node metastases were analyzed in consecutive 284 lung cancer patients with lobar-hilar and mediastinal lymph node dissection. Interlobar lymph node metastases were observed in 46 (16.2%) patients with no difference between right and left cases. On the right side, there was a significant difference in the frequency of inferior interlobar lymph node metastases between upper lobe and middle/lower lobe tumors (P=0.0004), but no difference in the frequencies of superior ones according to primary site. On the left, there was a significant difference in the frequency of interlobar lymph node metastases between upper lobe and lower lobe tumors (P=0.0021). In per-segment analyses, the frequency of inferior interlobar lymph node metastases in segments 1-3 and 6 was significantly lower than in the other total segments (P<0.0001) on the right, and that of interlobar lymph node metastases in the upper division segments (S1-3) was significantly lower than in the other total segments (P=0.0008) on the left. Even limited to one lobe, the patterns of interlobar lymph node metastases were different among the segments in the right lower lobe and the left upper lobe.
authors.affiliation: Department of Chest Surgery, Fukui Red Cross Hospital, 2-4-1 Tsukimi, Fukui 918-8501, Japan. akiray@mitene.or.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Yamanaka
authors.forename: Takashi
authors.initials: T
authors.lastname: Hirai
authors.forename: Ayuko
authors.initials: A
authors.lastname: Takahashi
authors.forename: Fumio
authors.initials: F
authors.lastname: Konishi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging