title: A prospective randomized trial of endoscopic versus conventional harvesting of the saphenous vein in coronary artery bypass surgery.
abstract: OBJECTIVE
  Our objectives were (1) to determine whether minimally invasive endoscopic harvesting of the saphenous vein reduces morbidity due to postoperative wound infection and pain with improved cosmetic results and mobilization as compared with the conventional technique and (2) to compare the histologic properties of the saphenous veins harvested conventionally and endoscopically.
  
  
  METHODS
  One hundred forty-four patients undergoing coronary artery bypass grafting were randomized to have vein harvesting performed by either the conventional (n = 72) or an endoscopic (n = 72) minimally invasive technique.
  
  
  RESULTS
  Vein harvest time (open leg wound time) was significantly reduced in the endoscopic group (27.6 vs 64.4 minutes; P <.0001). The rate of leg wound infection was significantly reduced in the endoscopic group (4.3%) as compared with the conventional group (24.6%), a relative risk reduction of 83% (95% confidence interval: 36%-129%; P =.0006). The majority of infections (84.2%) occurred after hospital discharge. Postoperative leg pain, mobilization, and overall patient satisfaction were also significantly improved in the endoscopic group. Double blinded histologic assessment of harvested vein (n = 28) showed no evidence of any clinically important significant damage to the specimens in either group.
  
  
  CONCLUSIONS
  In this prospective randomized trial, endoscopic harvesting of the saphenous vein significantly reduced postoperative leg wound complications, including infection, and improved patient satisfaction as compared with the conventional harvesting technique. There were no significant histologic differences between the conventional and endoscopically harvested saphenous veins.
authors.affiliation: Department of Surgery, University of Western Ontario, London, Ontario, Canada.
authors.forename: Bob
authors.initials: B
authors.lastname: Kiaii
authors.forename: Byung C
authors.initials: BC
authors.lastname: Moon
authors.forename: David
authors.initials: D
authors.lastname: Massel
authors.forename: Yves
authors.initials: Y
authors.lastname: Langlois
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Austin
authors.forename: Andrea
authors.initials: A
authors.lastname: Willoughby
authors.forename: C
authors.initials: C
authors.lastname: Guiraudon
authors.forename: Craig R
authors.initials: CR
authors.lastname: Howard
authors.forename: L Ray
authors.initials: LR
authors.lastname: Guo
mesh_terms: D001026:Coronary Artery Bypass; D004311:Double-Blind Method; D004724:Endoscopy; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000453:epidemiology; D017060:Patient Satisfaction; D011446:Prospective Studies; D012501:Saphenous Vein / Q000637:transplantation*; D013530:Surgical Wound Infection / Q000453:epidemiology; D020858:Tissue and Organ Harvesting; D016138:Walking