title: Lyn/CD22/SHP-1 and their importance in autoimmunity.
authors.affiliation: Medical Genome Centre, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia.
authors.forename: Julie
authors.initials: J
authors.lastname: Blasioli
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Goodnow
mesh_terms: D020816:Amino Acid Motifs; D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology; D000818:Animals; D015703:Antigens, CD / Q000276:immunology*; D000944:Antigens, Differentiation, B-Lymphocyte / Q000276:immunology*; D001327:Autoimmune Diseases / Q000276:immunology; D015551:Autoimmunity / Q000276:immunology*; D016175:B-Lymphocyte Subsets / Q000276:immunology*; D020013:Calcium Signaling / Q000276:immunology; D015815:Cell Adhesion Molecules; D005786:Gene Expression Regulation / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D047908:Intracellular Signaling Peptides and Proteins; D037102:Lectins; D008213:Lymphocyte Activation; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D018448:Models, Immunological; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D053824:Protein Tyrosine Phosphatase, Non-Receptor Type 6; D017027:Protein Tyrosine Phosphatases / Q000276:immunology*; D011505:Protein-Tyrosine Kinases / Q000276:immunology; D011947:Receptors, Antigen, B-Cell / Q000276:immunology; D051918:Sialic Acid Binding Ig-like Lectin 2; D015398:Signal Transduction / Q000276:immunology*; D014157:Transcription Factors / Q000378:metabolism; D019061:src-Family Kinases / Q000276:immunology*
chemical_list: D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; C497867:CD22 protein, human; C497868:Cd22 protein, mouse; D015815:Cell Adhesion Molecules; D047908:Intracellular Signaling Peptides and Proteins; D037102:Lectins; D011947:Receptors, Antigen, B-Cell; D051918:Sialic Acid Binding Ig-like Lectin 2; D014157:Transcription Factors; D011505:Protein-Tyrosine Kinases; C060902:lyn protein-tyrosine kinase; D019061:src-Family Kinases; C509249:PTPN6 protein, human; D053824:Protein Tyrosine Phosphatase, Non-Receptor Type 6; D017027:Protein Tyrosine Phosphatases; C509248:Ptpn6 protein, mouse