title: Recurrent lentigo maligna melanoma: regression associated with local azelaic acid 20%.
abstract: Azelaic acid has been used to treat different hyperpigmentary disorders because of its antimelanocyte activity. The efficacy of azelaic acid in the treatment of lentigo maligna and melanoma has already been described and this local treatment is considered by some as an alternative agent when other forms of therapy are not realisable. Here we report a case of a patient with local recurrence of a stage IV lentigo maligna melanoma of the cheek which cleared after treatment with azelaic acid cream 20%.
authors.affiliation: Department of Dermatology, Erasme University Hospital, Brussels, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Vereecken
authors.forename: M
authors.initials: M
authors.lastname: Heenen
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002610:Cheek; D003879:Dermatologic Agents / Q000627:therapeutic use*; D003998:Dicarboxylic Acids / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000188:drug therapy*; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D003879:Dermatologic Agents; D003998:Dicarboxylic Acids; C010038:azelaic acid