Palate ulcer due to mucormycosis.
Mucormycosis is caused by fungi of the order Mucorales and is one of the most rapidly fatal fungal infections known to man. Rhinocerebral mucormycosis is the most common type and its extension to the orbit and brain is quite usual. Location of mucormycosis on the palate is a rare and late occurrence. A case of deep hard palate ulcer due to sinonasal mucormycosis in a 79-year-old man is reported. He was successfully treated with a combination of surgical debridement and systemic liposomal amphotericin B administration for six weeks. By presenting this case report we would like to point out that mucormycosis should be included in the differential diagnosis of hard palate ulcers.
Kyrmizakis
Dionysios E
DE
Department of Otolaryngology, University of Crete, Greece. dkyrmiz@yahoo.com
Doxas
Panagiotis G
PG
Hajiioannou
Jiannis K
JK
Papadakis
Chariton E
CE
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D004338:Drug Combinations; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D019226:Oral Ulcer / Q000188:drug therapy / Q000382:microbiology*; D021362:Palate, Hard / Q000382:microbiology*; D010713:Phosphatidylcholines / Q000627:therapeutic use; D010715:Phosphatidylglycerols / Q000627:therapeutic use
D000935:Antifungal Agents; D004338:Drug Combinations; D010713:Phosphatidylcholines; D010715:Phosphatidylglycerols; C068538:liposomal amphotericin B; D000666:Amphotericin B