title: Further supporting evidence of beneficial subthalamic stimulation in Parkinson's patients.
abstract: Twenty-two patients with Parkinson's disease were treated by implanting electrodes in the subthalamic nucleus. The follow-up evaluation was conducted at one (22 patients) and two years (9 patients). Significant improvement in the Unified PD Rating Scale scores was found. Tremor diminished 100% in the on drug/on stimulation and 70% off drug/on stimulation state. Rigidity decreased by 68% in the on drug/on stimulation and by 52% in off drug/on stimulation state. Subthalamic stimulation is reliable.
authors.affiliation: Neurología Experimental, Departamento Investigación, Hospital Ramón y Cajal, Madrid 28034, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Figueiras-Méndez
authors.forename: I
authors.initials: I
authors.lastname: Regidor
authors.forename: C
authors.initials: C
authors.lastname: Riva-Meana
authors.forename: C M
authors.initials: CM
authors.lastname: Magariños-Ascone
mesh_terms: D000368:Aged; D004599:Electric Stimulation Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000628:therapy*; D020531:Subthalamic Nucleus / Q000502:physiology*; D016896:Treatment Outcome