title: Reactive dienes: intramolecular aromatic oxidation of 3-(2-hydroxyphenyl)-propionic acids.
abstract: [reaction: see text] Treatment of 3-(2-hydroxyphenyl)-propionic acids with a hypervalent iodine reagent in the presence of a dienophile initiates a tandem intramolecular aromatic oxidation/Diels-Alder reaction. Herein we report (1) investigations on the scope and limitations of this novel reaction combination and (2) preliminary diastereoselectivity studies using alpha- and beta-substituted acids.
authors.affiliation: Sterling Chemistry Laboratory, Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107, USA.
authors.forename: Ioana
authors.initials: I
authors.lastname: Drutu
authors.forename: Jón T
authors.initials: JT
authors.lastname: Njardarson
authors.forename: John L
authors.initials: JL
authors.lastname: Wood