[The application of BTA stat in the diagnosis of bladder tumor and hematuria].
OBJECTIVE
To analyze the value of the Bard BTA Stat for the diagnosis of bladder tumor and hematuria in order to find a new, noninvasive examination method.


METHODS
BTA Stat, an one step monoclonal antibody immunofluorescence analysis that qualitatively detects the presence of bladder tumor associated antigen (hCFHrp), was used. 65 patients with hematuria, 71 patients with bladder transitional cell carcinoma, and 10 normal people underwent voided urine BTA Stat analysis.


RESULTS
The specificity of the technique for patients with bladder transitional cell carcinoma and hematuria was 84.6% and 31.1% respectively, with a sensitivity of 73.7% and 90.0% respectively.


CONCLUSIONS
BTA Stat was considered a convenient, rapid and noninvasive method in the diagnosis of bladder tumor. However, the results were interfered by the presence of erythrocyte in urine, infection, urinary lithiasis. This method is proved to be useful in the surveillance of bladder tumor.
Wang
X
X
Department of Urology, People's Hospital, Beijing Medical University, Beijing 100044.
Xu
K
K
Zhu
J
J
Hou
S
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000951:Antigens, Neoplasm / Q000652:urine; D014408:Biomarkers, Tumor / Q000652:urine*; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis*; D005260:Female; D006417:Hematuria / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; C112999:bladder tumor-associated antigen