title: Amino(hydroxymethyl)cyclopentanetriols, an emerging class of potent glycosidase inhibitors--Part I: Synthesis and evaluation of beta-D-pyranoside analogues in the manno, gluco, galacto, and GlcNAc series.
authors.affiliation: Institut für Organische Chemie, Universität Stuttgart, Pfaffenwaldring 55, 70569 Stuttgart, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Kleban
authors.forename: P
authors.initials: P
authors.lastname: Hilgers
authors.forename: J N
authors.initials: JN
authors.lastname: Greul
authors.forename: R D
authors.initials: RD
authors.lastname: Kugler
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Picasso
authors.forename: P
authors.initials: P
authors.lastname: Vogel
authors.forename: V
authors.initials: V
authors.lastname: Jäger
mesh_terms: D000117:Acetylglucosamine / Q000737:chemistry; D000606:Amino Sugars / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D005690:Galactose / Q000737:chemistry; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006027:Glycosides / Q000737:chemistry; D020128:Inhibitory Concentration 50; D007700:Kinetics; D008358:Mannose / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D000606:Amino Sugars; D003517:Cyclopentanes; D004791:Enzyme Inhibitors; D006027:Glycosides; C013904:cyclopentane-1,2,3-triol; D006026:Glycoside Hydrolases; D008358:Mannose; D000117:Acetylglucosamine; D005690:Galactose