title: 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline: a novel and chemoselective tert-butoxycarbonylation reagent.
abstract: [reaction: see text] The use of 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI) as tert-butoxycarbonylation reagent for aromatic and aliphatic amine hydrochlorides and phenols in the absence of a base has been demonstrated. The reactions proceed chemoselectively in high yield under mild conditions.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tohoku Pharmaceutical University, Sendai 981-8558, Japan.
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Ouchi
authors.forename: Yukako
authors.initials: Y
authors.lastname: Saito
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Hiroki
authors.initials: H
authors.lastname: Takahata