(1R,3S)-Camphoramic acid.
The title chiral compound, 3-aminocarbonyl-1,2,2-trimethylcyclopentane-1-carboxylic acid, C(10)H(17)NO(3), was prepared from (1R,3S)-camphoric acid. The five-membered ring adopts a conformation which is intermediate between a twist and an envelope. Elongations of the C-C bonds and contractions of the C-C-C bond angles are observed within the five-membered ring. A (1)H NMR spectrum was recorded to assist in distinguishing the amide group from the carboxyl group.
Nie
Jing-Jing
JJ
Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China.
Xu
Duan-Jun
DJ
Hu
Zi-Qiang
ZQ
Xu
Yuan-Zhi
YZ
Wu
Jing-Yun
JY
Chiang
Michael Y
MY