Acute abdomen during adjuvant chemotherapy: superior mesenteric artery thrombosis associated with CMF chemotherapy.
We report a case of superior mesenteric artery thrombosis in a 57-year-old woman undergoing chemotherapy for T1N1M0, breast cancer. Although cancer itself is associated with an increased risk of thrombotic events, treatment with chemotherapy and/or tamoxifen in breast cancer patients increases this risk. Most cases reported are of venous thromboembolism; arterial events are rare.
Sugden
E M
EM
Churchill Hospital, Oxford, Banbury, UK.
Griffiths
C L
CL
Greywoode
G I
GI
Lewis
S M
SM
D000006:Abdomen, Acute / Q000139:chemically induced*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D017024:Chemotherapy, Adjuvant; D003520:Cyclophosphamide / Q000009:adverse effects*; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D017538:Mesenteric Artery, Superior / Q000187:drug effects; D008641:Mesenteric Vascular Occlusion / Q000139:chemically induced*; D008727:Methotrexate / Q000009:adverse effects*; D008875:Middle Aged; D013927:Thrombosis / Q000139:chemically induced*
D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate