Update on the epidemiology and transmission of Pneumocystis carinii.
Although Pneumocystis carinii pneumonia is one of the leading causes of morbidity and mortality among patients with the acquired immunodeficiency syndrome, many questions about its epidemiology and transmission remain unanswered. Whereas traditional theory postulates that the disease results from reactivation of latent infection, recent data suggest that active acquisition of infection, either through environmental exposure or person-to-person transmission, may occur. This review summarizes the current state of knowledge about the epidemiology and transmission of P. carinii and reports on evolving techniques that may improve our understanding of this organism in the future.
Morris
Alison
A
Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA. morrisam@msx.upmc.edu
Beard
C Ben
CB
Huang
Laurence
L
D000818:Animals; D002675:Child, Preschool; D004783:Environmental Microbiology; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D011010:Pneumocystis / Q000254:growth & development; D011020:Pneumonia, Pneumocystis / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission*; D051381:Rats