title: Abnormal T lymphocyte signal transduction in systemic lupus erythematosus.
authors.affiliation: Section on Rheumatology & Clinical Immunology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, N.C., USA. gmkammer@wfubmc.edu
authors.forename: Gary M
authors.initials: GM
authors.lastname: Kammer
authors.forename: George C
authors.initials: GC
authors.lastname: Tsokos
mesh_terms: D021581:Active Transport, Cell Nucleus; D000818:Animals; D001327:Autoimmune Diseases / Q000235:genetics / Q000276:immunology*; D020013:Calcium Signaling; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics; D051786:Cyclic AMP Response Element Modulator; D017868:Cyclic AMP-Dependent Protein Kinases / Q000172:deficiency / Q000502:physiology; D004268:DNA-Binding Proteins / Q000502:physiology; D004195:Disease Models, Animal; D020022:Genetic Predisposition to Disease; D006801:Humans; D015544:Inositol 1,4,5-Trisphosphate / Q000502:physiology; D007376:Interleukin-2 / Q000096:biosynthesis; D007527:Isoenzymes / Q000502:physiology; D017493:Leukocyte Common Antigens / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000235:genetics / Q000276:immunology*; D020935:MAP Kinase Signaling System; D008565:Membrane Proteins / Q000276:immunology; D051379:Mice; D019463:Mice, Inbred MRL lpr; D018448:Models, Immunological; D016328:NF-kappa B / Q000172:deficiency / Q000378:metabolism; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D012097:Repressor Proteins; D015398:Signal Transduction / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D051996:Transcription Factor RelA
chemical_list: D004268:DNA-Binding Proteins; D007376:Interleukin-2; D007527:Isoenzymes; D008565:Membrane Proteins; D016328:NF-kappa B; D011948:Receptors, Antigen, T-Cell; D012097:Repressor Proteins; D051996:Transcription Factor RelA; C054979:antigen T cell receptor, zeta chain; D051786:Cyclic AMP Response Element Modulator; D015544:Inositol 1,4,5-Trisphosphate; D017868:Cyclic AMP-Dependent Protein Kinases; D017493:Leukocyte Common Antigens