title: Molecular cloning, gene localization, and structure of human cyclin B3.
abstract: Here we describe the molecular cloning of human cyclin B3, its localization, and its structure. It is localized in the subcentromeric region of the X chromosome, still not completely sequenced by the Human Genome Project. This cyclin B3 is unusually large for a mitotic cyclin. Its mRNAs were found in all tissues and were particularly abundant in testis. At least three splice variants were found in the ORF and three variants in the 5'UTR.
authors.affiliation: Laboratoire Arago, CNRS-UMR 7628/Université Paris VI, Banyuls-sur-mer, France.
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Lozano
authors.forename: Eric
authors.initials: E
authors.lastname: Perret
authors.forename: Philippe
authors.initials: P
authors.lastname: Schatt
authors.forename: Cécile
authors.initials: C
authors.lastname: Arnould
authors.forename: Gérard
authors.initials: G
authors.lastname: Peaucellier
authors.forename: André
authors.initials: A
authors.lastname: Picard
mesh_terms: D017398:Alternative Splicing; D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D019926:Cyclin B / Q000096:biosynthesis / Q000737:chemistry* / Q000235:genetics*; D016213:Cyclins / Q000096:biosynthesis / Q000737:chemistry* / Q000235:genetics*; D005091:Exons; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007438:Introns; D008297:Male; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000096:biosynthesis; D016415:Sequence Alignment; D013737:Testis / Q000378:metabolism; D014018:Tissue Distribution; D014960:X Chromosome
chemical_list: C503694:CCNB3 protein, human; D019926:Cyclin B; D016213:Cyclins; D012333:RNA, Messenger