Regulation of tumor necrosis factor-alpha production by a fungal metabolite, PR 1388.
Ichikawa
K
K
Exploratory Medicinal Sciences, PGRD, Nagoya Laboratories, Pfizer Pharmaceuticals Inc., Aichi, Japan. katsuomi.ichikawa@japan.pfizer.com
Inagaki
T
T
Kojima
Y
Y
Nakamura
T
T
Nishida
H
H
Ueno
Y
Y
Kojima
N
N
D000818:Animals; D001203:Ascomycota / Q000737:chemistry / Q000378:metabolism*; D001681:Biological Assay; D004224:Diterpenes / Q000378:metabolism* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008070:Lipopolysaccharides / Q000494:pharmacology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000096:biosynthesis*
D004224:Diterpenes; D008070:Lipopolysaccharides; C447460:PR 1388; D014409:Tumor Necrosis Factor-alpha