[Experimental study of the effect of Hpudiod cream on random flap survival in rats].
OBJECTIVE
To explore the effect of Hpudiod cream on blood circulation of flap.


METHODS
80 rats were casually divided into two groups: the experiment and the control group. A random flap was created on the back of the animal. Flap survival and necrosis were observed in the two groups. The flaps were examined histologically and the capillaries were counted.


RESULTS
On the 5th and 7th day after operation, the distant ends of the flaps necrosed in both groups. On the 5th day there was no significant difference between the two groups in the number of the capillary in the middle of the flap (P > 0.05). On the 7th day, the capillary in the middle of the flap increased in the treatment group(P < 0.05).


CONCLUSIONS
Hpudiod cream can improve the blood circulation of the random flap evidently.
Wang
Y
Y
Third People's Hospital of Datong, Datong 037008, China.
He
Y
Y
Shi
R
R
D000818:Animals; D001775:Blood Circulation / Q000187:drug effects*; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000494:pharmacology*; D008297:Male; D009336:Necrosis; D009824:Ointments; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012869:Skin Absorption / Q000187:drug effects; D013524:Surgical Flaps / Q000098:blood supply* / Q000473:pathology
D006495:Heparin, Low-Molecular-Weight; D009824:Ointments