title: Cerium(III) chloride promoted highly regioselective ring opening of epoxides and aziridines using NaN(3) in acetonitrile: a facile synthesis of 1,2-azidoalcohols and 1,2-azidoamines.
abstract: A convenient and efficient synthesis of 1,2-azidoalcohols and 1,2-azidoamines has been achieved by ring opening of epoxides and aziridines using cerium(III) chloride and sodium azide in acetonitrile. The reaction is highly regioselective and afforded the corresponding products in good to excellent yields under mild and neutral reaction conditions. The method is very rapid and equally compatible for both epoxides and aziridines.
authors.affiliation: Organic Division I, Indian Institute of Chemical Technology, Hyderabad 500 007, India. sabitha@iict.ap.nic.in
authors.forename: Gowravaram
authors.initials: G
authors.lastname: Sabitha
authors.forename: R Satheesh
authors.initials: RS
authors.lastname: Babu
authors.forename: M
authors.initials: M
authors.lastname: Rajkumar
authors.forename: J S
authors.initials: JS
authors.lastname: Yadav