title: Chronic vulvovaginitis caused by antibiotic-resistant Shigella flexneri in a prepubertal child.
abstract: A 7-year 8-month-old girl was diagnosed with a prolonged course of vulvovaginitis caused by Shigella flexneri. The child was symptomatic with intermittent vaginal bleeding, dysuria and foul smelling vaginal discharge for a 3-year period. Initial attempts to resolve the infection with successive courses of antibiotic therapy using ampicillin, trimethoprim-sulfamethoxazole, cefixime and amoxicillin/clavulanic acid failed. The child's infection was finally resolved by a 14-day course of ciprofloxacin.
authors.affiliation: Department of Pathology, University of Illinois College of Medicine, Chicago, IL 60612, USA.
authors.forename: Maria
authors.initials: M
authors.lastname: Baiulescu
authors.forename: Patricia R
authors.initials: PR
authors.lastname: Hannon
authors.forename: John F
authors.initials: JF
authors.lastname: Marcinak
authors.forename: William M
authors.initials: WM
authors.lastname: Janda
authors.forename: Paul C
authors.initials: PC
authors.lastname: Schreckenberger
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002648:Child; D002908:Chronic Disease; D002939:Ciprofloxacin / Q000627:therapeutic use*; D004351:Drug Resistance; D004405:Dysentery, Bacillary / Q000150:complications*; D005260:Female; D006801:Humans; D012763:Shigella flexneri / Q000302:isolation & purification / Q000472:pathogenicity*; D014848:Vulvovaginitis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin