[Genetic polymorphism of D16S539, D7S820 and D13S317 loci in the Kazak ethnic population].
OBJECTIVE
To analyze the genetic polymorphism of D16S539, D7S820 and D13S317 in Chinese Kazak ethnic population from Xinjiang.


METHODS
One hundred and two unrelated individuals and a sample of families (n=42) were investigated by multiplex amplification, 6% denaturing PAGE and silver staining. And, the obtained allele frequencies were compared with those of other populations.


RESULTS
Eight, seven, eight alleles were observed at the 3 STR loci respectively and the genotypes distributions were in accordance with Hardy-Weinberg equilibrium. The expected heterozygosities for these loci were 0.9439, 0.9356 and 0.9304; the calculated polymorphism formation content (PIC) was 0.9905; the discrimination power (DP), 0.9998; the paternity exclusion (PE), 0.9572. In addition, significant difference was found in comparison with other populations, and in the sample of families (n=42) no new mutations could be found.


CONCLUSIONS
The multiplex examination of 3 STR loci can be used in forensic identification and population genetics research.
Chen
Xueling
X
Department of Medical Immunology, Medical College of Shihezi University, Shihezi, Xinjiang, 832002 P. R. China. xuelingch@sina.com
Huang
Chen
C
Yuan
Yukang
Y
Liu
Riming
R
Xu
Jian
J
Song
Tusheng
T
Li
Shengbin
S
D002681:China / Q000208:ethnology; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences / Q000235:genetics*; D044465:White People / Q000235:genetics