A working model for the time sequence of genetic changes in breast tumorigenesis.
Singletary
S Eva
SE
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston 77030, USA.
D000818:Animals; D017209:Apoptosis; D001943:Breast Neoplasms / Q000235:genetics*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000235:genetics; D002453:Cell Cycle; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D018844:Cyclin-Dependent Kinases / Q000037:antagonists & inhibitors / Q000235:genetics; D016213:Cyclins / Q000235:genetics; D005260:Female; D016147:Genes, Tumor Suppressor / Q000502:physiology; D019254:Genes, bcl-2 / Q000502:physiology; D018773:Genes, erbB-1 / Q000502:physiology; D006801:Humans; D008957:Models, Genetic; D009362:Neoplasm Metastasis / Q000235:genetics; D009857:Oncogenes / Q000502:physiology; D013997:Time Factors; D014407:Tumor Cells, Cultured
D016213:Cyclins; D018844:Cyclin-Dependent Kinases