title: Advances DNA vaccines.
abstract: Extraordinary advances in biotechnology make DNA vaccines the most promising area of vaccinology. This article reviews the public health impact of vaccines in the 20th century, summarizes immunologic concepts, and updates the status of DNA vaccine development and its impact on clinical practice.
authors.affiliation: US Centers for Disease Control and Prevention, National Center for Infectious Diseases, International Emerging Infections Program, Bangkok, Thailand.
authors.forename: James Mark
authors.initials: JM
authors.lastname: Simmerman
mesh_terms: D003141:Communicable Diseases / Q000276:immunology*; D006801:Humans; D007114:Immunization / Q000379:methods* / Q000639:trends; D019444:Vaccines, DNA / Q000276:immunology* / Q000627:therapeutic use*; D014614:Vaccines, Synthetic / Q000276:immunology
chemical_list: D019444:Vaccines, DNA; D014614:Vaccines, Synthetic