title: [Incidence of carcinomas in goiters and their combination with Hashimoto's thyroiditis].
abstract: In the investigated group 300 patients were operated for a thyropathy mostly struma nodosa, tumours were proved in 69 cases; 38 of them were carcinomas of various extent and 3 of them were combined with Hashinoto's lymphomatous goitre. The overwhelming majority of the carcinomas were papillary carcinomas (22 cases). The incidence of papillary carcinoma in Hashimoto's goitre was about 8%; this fact calls for more attention to autoaggressive thyroiditis both in examination of surgical material, and during autopsies in middle-aged women, where this thyroiditis is often clinically silent. Our results suggest an increase in the incidence of carcinoma in Hashimoto's goitre and the generally accepted rarity of this coincidence is questioned. We recorded also a lower incidence of medullary carcinoma than the worldwide average and a more frequent incidence of mixed-type carcinoma.
authors.affiliation: II. chirurgická klinika LF MU, Brno. r.staffa@email.cz
authors.forename: R
authors.initials: R
authors.lastname: Staffa
authors.forename: E
authors.initials: E
authors.lastname: Jandousová
authors.forename: J
authors.initials: J
authors.lastname: Leypold
authors.forename: P
authors.initials: P
authors.lastname: Gladis
authors.forename: E
authors.initials: E
authors.lastname: Cerný
authors.forename: K
authors.initials: K
authors.lastname: Husek
mesh_terms: D000236:Adenoma / Q000150:complications; D002277:Carcinoma / Q000150:complications*; D005260:Female; D006042:Goiter / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000150:complications*; D013967:Thyroiditis, Autoimmune / Q000150:complications