title: Epigenetics: monoallelic expression in the immune system.
abstract: Epigenetic modifications to DNA and chromatin programme important genome functions including gene expression, chromosomal architecture and stability, and the maintenance of developmental states. Recent findings further implicate epigenetic modifications in the control of allelic choice in the immune system.
authors.affiliation: MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. car@mrc-lmb.cam.ac.uk
authors.forename: Cristina
authors.initials: C
authors.lastname: Rada
authors.forename: Anne C
authors.initials: AC
authors.lastname: Ferguson-Smith
mesh_terms: D000483:Alleles; D002454:Cell Differentiation; D002455:Cell Division; D004254:DNA Nucleotidyltransferases / Q000378:metabolism; D004261:DNA Replication; D005786:Gene Expression Regulation; D015321:Gene Rearrangement; D007107:Immune System / Q000378:metabolism*; D008214:Lymphocytes / Q000166:cytology / Q000378:metabolism*; D045567:VDJ Recombinases
chemical_list: D004254:DNA Nucleotidyltransferases; D045567:VDJ Recombinases