Methyl psilalate: a new antimicrobial metabolite from Psila boliviensis.
Psila boliviensis (Wedd.) Cabr. yielded a new phenylpropanoid, named methyl psilalate. The structure was established by means of standard spectroscopic techniques. The microbiological evaluation of the compound revealed antibacterial activity against Gram-positive and Gram-negative bacteria.
Erazo
Silvia
S
Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago, Chile. serazo@uchile.cl
Negrete
Rosa
R
Zaldívar
Mercedes
M
Backhouse
Nadine
N
Delporte
Carla
C
Silva
Irina
I
Belmonte
Eliana
E
López-Pérez
José Luis
JL
San Feliciano
Arturo
A
D000447:Aldehydes / Q000737:chemistry / Q000494:pharmacology*; D000475:Alkenes / Q000737:chemistry / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D019659:Asteraceae; D001419:Bacteria / Q000187:drug effects*; D002855:Chromatography, Thin Layer; D007199:Indians, South American; D009682:Magnetic Resonance Spectroscopy; D008519:Medicine, Traditional; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018520:Plant Shoots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
D000447:Aldehydes; D000475:Alkenes; D000900:Anti-Bacterial Agents; D010936:Plant Extracts; C452876:methyl psilalate