Comparison of the rheological properties of Advantage-S and Replens.
The rheological properties of Advantage-S and Replens were measured at body (37 degrees C) and room temperature (25 degrees C) over a range of physiologically relevant shear rates. The viscosity of Replens was found to differ from that of Advantage-S, particularly at room temperature. In addition, the two materials differed in their miscibility with a vaginal fluid simulant.
Owen
D H
DH
Department of Biomedical Engineering, Duke University, Durham, NC, USA. dhowen@acpub.duke.edu
Peters
J J
JJ
Katz
D F
DF
D000704:Analysis of Variance; D005260:Female; D005782:Gels / Q000737:chemistry; D006801:Humans; D008055:Lipids; D008153:Lubrication; D017137:Nonoxynol; D012212:Rheology; D013089:Spermatocidal Agents / Q000008:administration & dosage / Q000737:chemistry*; D013696:Temperature; D014621:Vagina / Q000187:drug effects / Q000502:physiology; D014622:Vaginal Creams, Foams, and Jellies / Q000008:administration & dosage / Q000737:chemistry*
D005782:Gels; D008055:Lipids; C085472:Replens; D013089:Spermatocidal Agents; D014622:Vaginal Creams, Foams, and Jellies; D017137:Nonoxynol