title: Effect of exercise training at different intensities on fat metabolism of obese men.
abstract: The present study investigated the effect of exercise training at different intensities on fat oxidation in obese men. Twenty-four healthy male obese subjects were randomly divided in either a low- [40% maximal oxygen consumption (VO(2 max))] or high-intensity exercise training program (70% VO(2 max)) for 12 wk, or a non-exercising control group. Before and after the intervention, measurements of fat metabolism at rest and during exercise were performed by using indirect calorimetry, [U-(13)C]palmitate, and [1,2-(13)C]acetate. Furthermore, body composition and maximal aerobic capacity were measured. Total fat oxidation did not change at rest in any group. During exercise, after low-intensity exercise training, fat oxidation was increased by 40% (P < 0.05) because of an increased non-plasma fatty acid oxidation (P < 0.05). High-intensity exercise training did not affect total fat oxidation during exercise. Changes in fat oxidation were not significantly different among groups. It was concluded that low-intensity exercise training in obese subjects seemed to increase fat oxidation during exercise but not at rest. No effect of high-intensity exercise training on fat oxidation could be shown.
authors.affiliation: Department of Human Biology, Nutrition, Toxicology, and Environmental Research Institute, Maastricht University, 6200 MD Maastricht, The Netherlands.
authors.forename: Dorien P C
authors.initials: DP
authors.lastname: van Aggel-Leijssen
authors.forename: Wim H M
authors.initials: WH
authors.lastname: Saris
authors.forename: Anton J M
authors.initials: AJ
authors.lastname: Wagenmakers
authors.forename: Joan M
authors.initials: JM
authors.lastname: Senden
authors.forename: Marleen A
authors.initials: MA
authors.lastname: van Baak
mesh_terms: D000328:Adult; D015444:Exercise / Q000502:physiology; D005223:Fats / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D010806:Physical Education and Training; D012146:Rest
chemical_list: D005223:Fats