title: The skin-lightening effects of artocarpin on UVB-induced pigmentation.
abstract: This study was conducted to evaluate the effects of the prenylated flavonol artocarpin from the heartwood of Artocarpus incisus on ultraviolet (UV)-induced hyperpigmentation of guinea pig skin. An efficient lightening effect was observed following topical application of artocarpin to UV-stimulated hyperpigmented dorsal skins of brownish guinea pigs.
authors.affiliation: Department of Forestry and Forest Products Science, Faculty of Agriculture, Kyushu University, Fukuoka, Japan. shimizu@agr.kyushu-u.ac.jp
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Shimizu
authors.forename: Ryuichiro
authors.initials: R
authors.lastname: Kondo
authors.forename: Kokki
authors.initials: K
authors.lastname: Sakai
authors.forename: Norio
authors.initials: N
authors.lastname: Takeda
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Nagahata
mesh_terms: D000818:Animals; D001104:Arbutin / Q000494:pharmacology; D002352:Carrier Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006168:Guinea Pigs; D037102:Lectins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D037241:Mannose-Binding Lectins; D008543:Melanins / Q000378:metabolism* / Q000528:radiation effects; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000378:metabolism; D029586:Moraceae; D037121:Plant Lectins; D011753:Pyrones / Q000494:pharmacology; D012880:Skin Pigmentation / Q000187:drug effects* / Q000528:radiation effects; D014466:Ultraviolet Rays
chemical_list: D002352:Carrier Proteins; D037102:Lectins; D037241:Mannose-Binding Lectins; D008543:Melanins; D037121:Plant Lectins; D011753:Pyrones; C090683:artocarpin lectin; C011890:kojic acid; D001104:Arbutin; D014442:Monophenol Monooxygenase