Griseofulvin-containing medium for simplified diagnosis of dermatophytosis.
By inoculating paired tubes of standard Sabouraud dextrose-chloramphenicol-cycloheximide media, one of which contained in addition 20 micrograms/ml of griseofulvin, 86 of 88 griseofulvin-sensitive dermatophytes were recognized in 226 primary isolation cultures. Most yeast, bacteria, and mold contaminants were not selectively inhibited by the media. The method facilitates the selection of patients for oral griseofulvin therapy by those with relatively little training in mycology.
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Department of Dermatology, University of Miami School of Medicine, Miami, Fla., USA.
Rebell
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D003470:Culture Media; D003881:Dermatomycoses / Q000382:microbiology*; D004821:Epidermophyton / Q000302:isolation & purification; D006118:Griseofulvin / Q000494:pharmacology*; D006801:Humans; D008828:Microbiological Techniques; D008864:Microsporum / Q000302:isolation & purification*; D014249:Trichophyton / Q000302:isolation & purification*
D003470:Culture Media; D006118:Griseofulvin