title: [Current clinical aspects of HIV/AIDS].
abstract: OF NEW CLINICAL DEMONSTRATIONS: Since the use of HAART, morbidity and mortality in HIV-infected patients have decreased dramatically. But increased survival in these patients is associated with other diseases (malignant diseases, inflammatory reactions after initiation of HAART) and with drug toxicity (lipodystrophy, mitochondrial toxicity). TRANSMISSION AND REVELATION: Despite widespread information on HIV, new HIV-infected patients with an AIDS-defining illness are still detected. At present, heterosexuality is the most frequent risk factor for HIV-infection (51%). Pneumocystis pneumonia remains the most common opportunistic illness in HIV-infected patients (28%).
authors.affiliation: Service des Maladies infectieuses et tropicales, Groupe Hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, F75013 Paris. valerie.zeller@psl.ap-hop-paris.fr
authors.forename: V
authors.initials: V
authors.lastname: Zeller
authors.forename: E
authors.initials: E
authors.lastname: Caumes
authors.forename: P
authors.initials: P
authors.lastname: Bossi
authors.forename: F
authors.initials: F
authors.lastname: Bricaire
authors.forename: C
authors.initials: C
authors.lastname: Katlama
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D006509:Hepatitis B / Q000150:complications; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D016867:Immunocompromised Host; D008060:Lipodystrophy / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis; D011247:Pregnancy; D011379:Prognosis; D012514:Sarcoma, Kaposi / Q000453:epidemiology; D012878:Skin Neoplasms / Q000453:epidemiology; D012907:Smoking / Q000009:adverse effects
chemical_list: D019380:Anti-HIV Agents