Palladium-catalyzed stereocontrolled vinylation of azoles and phenothiazine.
[reaction: see text] Vinylation of various azoles (pyrrole, indole, carbazole, and their derivatives) and phenothiazine with vinyl bromides catalyzed by palladium-phosphine complexes results in the respective N-vinylazoles in 30-99% yields. This reaction with cis- and trans-beta-bromostyrenes is stereospecific giving the respective products with full retention of configuration.
Lebedev
Artyom Y
AY
Department of Chemistry, Moscow State University, V-234, Moscow 119899, Russian Federation.
Izmer
Vyatcheslav V
VV
Kazyul'kin
Denis N
DN
Beletskaya
Irina P
IP
Voskoboynikov
Alexander Z
AZ