[The relationship between operation on gastrointestinal cancer and single cells metastasis via portal vein].
OBJECTIVE
To confirm the effect of radical operation on single cells metastasis of gastrointestinal cancer.


METHODS
One hundred and seventy two patients with gastrointestinal cancer were divided randomly into group I (111 cases, ordinary operation) and group II (61 cases, operation after ligation of drained vessels). Catheters were inserted into the portal vein during operation. Blood was aspirated and contrifugated. Anti-EMA monoclonal antibody marked the cancer cells, which were shown by ABC immunohistochemical staining.


RESULTS
In the examinate group, 72 cases of gastrointestinal cancer were found positive cells among 111 cases (positive rate 64.9%). In the control group, 61 cases were tested and 13 cases were found positive cells (positive rate 21.3%) with a highly significant difference between the two groups (P < 0.005).


CONCLUSIONS
Ligating the relative blood vessel before the radical operation can prevent single cancer cells from metastasis via portal vein.
Zhao
Z
Z
Department of General Surgery, Beithune International Peace Hospital, Shijiazhuang 050082.
Wang
S
S
Jiao
X
X
Chen
J
J
Hou
H
H
Shao
S
S
Wang
W
W
D000328:Adult; D000368:Aged; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating; D011169:Portal Vein / Q000473:pathology