Cutaneous candidosis in immunosuppressed patients.
One-hundred patients with candidosis of the skin, mucous membranes and nail plates (confirmed by cultivation) were examined. Topical or systemic antimycotic treatment was successful in 58 patients. After a complete evaluation, 42 patients were found to suffer from factors supporting candidosis--diabetes mellitus (12), anemia (3) and various local factors (10 patients); 27 patients showed a deficiency in cell-mediated immunity. In addition to intensive antimycotic therapy, successful treatment is affected by the actual immunity level and can be ensured by efficient immunomodulation treatment of immunodeficiency.
Jautová
J
J
Department of Dermatology, Faculty of Medicine, Safárik University, 040 66 Kosice, Slovakia.
Baloghová
J
J
Dorko
E
E
Pilipcinec
E
E
Svický
E
E
Danko
J
J
Tkáciková
L
L
D000908:Antibodies, Fungal / Q000097:blood; D000935:Antifungal Agents / Q000627:therapeutic use; D000936:Antigen-Antibody Complex / Q000097:blood; D002175:Candida / Q000145:classification / Q000472:pathogenicity*; D002179:Candidiasis, Cutaneous / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D016867:Immunocompromised Host; D010587:Phagocytosis; D012307:Risk Factors; D013601:T-Lymphocytes / Q000276:immunology
D000908:Antibodies, Fungal; D000935:Antifungal Agents; D000936:Antigen-Antibody Complex