[The effects of moderate acute normovolemic hemodilution on intestinal oxygen supply and consumption in anesthetized cats].
OBJECTIVE
To study the effects of moderate acute normovolemic hemodilution on the intestinal blood perfusion and oxygen supply in cats.


METHODS
15 domestic male cats were hemodiluted with Haemaccel. HR, MAP, lactate concentration in superior mesenteric vein (LAC), superior mesenteric artery blood flow (SMABF), superior mesenteric artery and venous blood gas analysis were recorded and the intestinal oxygen delivery (DO(2)), oxygen consumption (VO(2)) and oxygen extraction (EO(2)) were calculated before and after hemodilution.


RESULTS
SMABF increased obviously (P < 0.05), intestinal DO(2) and EO(2) did not change (P > 0.05) but VO(2) increased (P < 0.05), and LAC in superior mesenteric vein did not increase.


CONCLUSIONS
Moderate acute normovolemic hemodilution with Haemaccel do not alter intestinal oxygen delivery by increasing the superior mesenteric blood flow. It means that intestinal mucosa ischemia does not happen during moderate acute normovolemic hemodilution.
Wu
J
J
Department of Anesthesiology, First Affiliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 510081.
Mo
L
L
Tan
J
J
Peng
W
W
D000818:Animals; D001784:Blood Gas Analysis; D002415:Cats; D006438:Hemodilution / Q000379:methods*; D007413:Intestinal Mucosa / Q000378:metabolism*; D008297:Male; D017538:Mesenteric Artery, Superior / Q000502:physiology; D010101:Oxygen Consumption; D011097:Polygeline / Q000627:therapeutic use; D012039:Regional Blood Flow
D011097:Polygeline