Levels of circulating intercellular adhesion molecule-1 in patients with Behçet's disease.
The purpose of this study was to investigate the possible relationship between circulating intercellular adhesion molecule-1 (cICAM-1) plasma levels and Behçet's disease. Plasma levels of cICAM-1 were measured in 44 patients with Behçet's disease and in 30 healthy controls. cICAM-1 levels were higher in patients with Behçet's disease than in the controls (P=0.001). The difference was more marked between patients with active Behçet's disease and controls (P < 0.001). cICAM-1 levels were also higher in patients with active Behçet's disease than in those with inactive disease (P<0.001). cICAM-1 seems to be related to disease activity in Behçet's disease. It may be useful in assessing disease activity in Behçet's disease, as well as in monitoring response to treatment.
Saglam
Kenan
K
Department of Internal Medicine, Ankara, Turkey. ksaglam@gata.edu.tr
Yilmaz
M Ilker
MI
Saglam
Ayse
A
Ulgey
Mete
M
Bulucu
Fatih
F
Baykal
Yavuz
Y
D000328:Adult; D001528:Behcet Syndrome / Q000097:blood* / Q000503:physiopathology*; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D015331:Cohort Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D008297:Male; D012016:Reference Values; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
D015415:Biomarkers; D018799:Intercellular Adhesion Molecule-1