The influence of temperature, salt and pH on the inhibitory effect of reuterin on Escherichia coli.
The inhibitory effect of reuterin on Escherichia coli K12 was investigated at different conditions of temperature (10-30 degrees C), pH (4.5-6.5), and NaCl (0.5-3% (w/v)). The maximum specific growth rate as a function of the different environmental conditions was modelled with a polynomial model. At increasing temperatures, there was an increasing effect of reuterin, whereas neither pH nor salt showed interactions with the effect of reuterin. The model was validated against new experimental data and proved to perform satisfactorily based on the bias and accuracy factors.
Rasch
Maria
M
Department of Dairy and Food Science, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark. mra@kvl.dk
D000447:Aldehydes; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development*; D005985:Glyceraldehyde / Q000031:analogs & derivatives; D006131:Growth Inhibitors / Q000096:biosynthesis / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008954:Models, Biological; D011309:Preservation, Biological / Q000379:methods*; D011407:Propane; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012965:Sodium Chloride / Q000494:pharmacology*; D013696:Temperature
D000447:Aldehydes; D000900:Anti-Bacterial Agents; D006131:Growth Inhibitors; C047158:3-hydroxypropionaldehyde; D005985:Glyceraldehyde; D012965:Sodium Chloride; D011407:Propane