Preoperative hyperthermochemoradiotherapy for esophageal carcinoma.
BACKGROUND
In order to acquire an improved prognosis, preoperative hyperthermia combined with chemotherapy and radiotherapy (HCR) has been performed in our department for patients with esophageal carcinoma.


METHODS
The experimental and clinical investigations that have been continuously performed in our department were introduced with regard to the therapeutic effect brought by HCR for carcinoma, chiefly for esophageal carcinoma.


RESULTS
A series of our investigations have demonstrated the excellent anticancer effect of HCR for esophageal carcinoma.


CONCLUSIONS
Preoperative HCR has contributed to improvements in the prognosis of patients with esophageal carcinoma and is expected to make marked progress in the future with further development of anticancer agents and improvements in the hyperthermia devices.
Nozoe
Tadahiro
T
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi-Ward, Fukuoka, Japan.
Saeki
Hiroshi
H
Ito
Shuhei
S
Ohga
Takefumi
T
Kitamura
Kaoru
K
D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000401:mortality / Q000601:surgery / Q000628:therapy; D006801:Humans; D006979:Hyperthermia, Induced; D011300:Preoperative Care; D011878:Radiotherapy; D016032:Randomized Controlled Trials as Topic; D015996:Survival Rate
D000970:Antineoplastic Agents