title: A new trihydroxy fatty acid from the ascomycete, Chinese truffle Tuber indicum.
abstract: From the chloroform/methanol extract of the fruiting bodies of the ascomycete Chinese truffle Tuber indicum Cooke et Massee, a new trihydroxylated monounsaturated fatty acid (1) has been isolated. The structure of this new linoleic acid-derived metabolite was established as 9,10,11-trihydroxy-(12Z)-12-octadecenoic acid by means of spectroscopic and chemical methods. The fatty acid composition of the chloroform-soluble fraction of this fungus was analyzed by gas chromatography-mass spectrometry. The content of the predominant unsaturated fatty acids (oleic and linoleic acids) is as high as 68%. The use of dimethyl disulfide adduct was effective in the determination of the position of the double bond, and the glycol oxidation fission reaction with sodium metaperiodate supported on silica gel was helpful in establishing the location of the trihydroxylic groups in the new fatty acid.
authors.affiliation: College of Life Sciences, Northwest Science & Technology University of Agriculture and Forestry, Yangling, Shaanxi, People's Republic of China. jinminggao@sohu.com
authors.forename: J M
authors.initials: JM
authors.lastname: Gao
authors.forename: C Y
authors.initials: CY
authors.lastname: Wang
authors.forename: A L
authors.initials: AL
authors.lastname: Zhang
authors.forename: J K
authors.initials: JK
authors.lastname: Liu
mesh_terms: D001203:Ascomycota / Q000737:chemistry* / Q000378:metabolism; D002681:China; D005227:Fatty Acids / Q000096:biosynthesis / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
chemical_list: D005227:Fatty Acids