Development of wheezing disorders and asthma in preschool children.
Recent longitudinal studies have shed light on the pathogenesis and progression of asthma. The patterns of expression of childhood asthma that persist into adult life have been explored. Distinct asthma phenotypes (transient wheezing, nonatopic wheezing, and atopy-associated asthma) have been identified. Defining which children are at risk for persistent asthma could allow for better management and, potentially, for reduced morbidity and mortality.
Martinez
Fernando D
FD
University of Arizona, Tucson, Arizona, USA. fernando@resp-sci.arizona.edu
D000328:Adult; D000367:Age Factors; D000402:Airway Obstruction / Q000503:physiopathology; D001249:Asthma / Q000145:classification / Q000503:physiopathology* / Q000821:virology; D002654:Child Care; D002675:Child, Preschool; D015331:Cohort Studies; D018450:Disease Progression; D005541:Forced Expiratory Volume; D006801:Humans; D006967:Hypersensitivity / Q000150:complications; D007223:Infant; D008137:Longitudinal Studies; D009679:Nuclear Family; D010641:Phenotype; D012135:Respiratory Sounds / Q000503:physiopathology*; D018357:Respiratory Syncytial Virus Infections / Q000150:complications / Q000503:physiopathology