title: [Changes of interleukin-2 and soluble interleukin-2 receptor serum level and multiple organ dysfunction syndrome in severely traumatic patients].
abstract: OBJECTIVE
  To evaluate the role in the changes of interleukin-2 (IL-2) and soluble interleukin-2R (sIL-2R) serum level in the mechanism of post-traumatic multiple organ dysfunction syndrome (MODS).
  
  
  METHODS
  59 severe traumatic patients were divided into MODS group (n = 24) and non-MODS group (n = 35) according to the occurrence of MODS after trauma. The changes in IL-2 and sIL-2R serum level were observed by enzyme linked immunoabsorbed assay (ELISA). Sera from 30 healthy individuals were used as normal controls.
  
  
  RESULTS
  The serum level of sIL-2R was increased and that of IL-2 decreased in 59 traumatic patients. These changes were more marked in the MODS group than in non-MODS group (p < 0.05).
  
  
  CONCLUSIONS
  The changes in IL-2 and sIL-2R serum level after trauma might participate in the mechanism of post-traumatic MODS.
authors.affiliation: Hainan Provincial People's Hospital, Haikou 570311.
authors.forename: Z
authors.initials: Z
authors.lastname: He
authors.forename: S
authors.initials: S
authors.lastname: Wang
authors.forename: Z
authors.initials: Z
authors.lastname: Su
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.forename: J
authors.initials: J
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D016638:Critical Illness; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology*; D015375:Receptors, Interleukin-2 / Q000097:blood*; D014947:Wounds and Injuries / Q000097:blood* / Q000150:complications
chemical_list: D007376:Interleukin-2; D015375:Receptors, Interleukin-2