Growth hormone treatment does not alter lower limb asymmetry in children with Russell-Silver syndrome.
BACKGROUND
Growth hormone (GH) treatment has been proven to have a beneficial effect on growth in children with Russell-Silver syndrome (RSS).


METHODS
We describe 7 prepubertal children with RSS and lower limb asymmetry treated with GH for 3 years.


RESULTS
There was a significant increase in height without any significant change in the asymmetry.


CONCLUSIONS
We conclude that the rapid growth acceleration to GH treatment does not alter the lower limb asymmetry in children with RSS.
Rizzo
V
V
Department of Paediatric Endocrinology, Great Ormond Street Hospital for Children and Middlesex Hospital (UCLH), London, UK.
Traggiai
C
C
Stanhope
R
R
D002648:Child; D002675:Child, Preschool; D000013:Congenital Abnormalities; D005260:Female; D005317:Fetal Growth Retardation / Q000150:complications*; D006130:Growth Disorders / Q000150:complications* / Q000188:drug therapy*; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007870:Leg Length Inequality / Q000150:complications* / Q000473:pathology*; D008297:Male; D013577:Syndrome
D013006:Growth Hormone