New ursane-type triterpenic esters from the stem bark of Thevetia peruviana.
Phytochemical studies on the stem bark of Thevetia peruviana resulted in the isolation of six new ursane-type triterpenes, named peruvianursenyl acetate A, peruvianursenyl acetate B, isolupenyl acetate, peruvianursenyl acetate C, lupedienyl acetate and peruvianursenyl glucoside along with two known triterpenoids, namely alpha-amyrin acetate and lupeol acetate. The structures of the new phytoconstituents have been established as 23--nor methyl urs-12-en-4 alpha-ethylenic-18 alpha-H-3 beta-yl acetate, urs-5.21-dien-18 alpha-H-3 beta-yl acetate, lup-20 (29)-en-3 alpha-yl acetate, urs-12 en-18 alpha-H-3 beta-yl acetate, lup-5,20 (29)-dien-3 beta-yl acetate, and urs-12-en-18 alpha-H-3-O-beta-D-glucopyranoside, respectively.
Ali
M
M
Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, India. m.ali@mail.usa.com.hascritto
Ravinder
E
E
Ramachandram
R
R
D004952:Esters / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D007194:India; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010084:Oxidation-Reduction; D019441:Plant Epidermis / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D004952:Esters; D007202:Indicators and Reagents; D014315:Triterpenes