title: INCLUSive: integrated clustering, upstream sequence retrieval and motif sampling.
abstract: INCLUSive allows automatic multistep analysis of microarray data (clustering and motif finding). The clustering algorithm (adaptive quality-based clustering) groups together genes with highly similar expression profiles. The upstream sequences of the genes belonging to a cluster are automatically retrieved from GenBank and can be fed directly into Motif Sampler, a Gibbs sampling algorithm that retrieves statistically over-represented motifs in sets of sequences, in this case upstream regions of co-expressed genes.
authors.affiliation: ESAT_ SISTA/COSIC, KULeuven, Kasteelpark Arenberg 10, 3001 Leuven-Heverlee, Belgium. Gert.Thijs@esat.kuleuven.ac.be
authors.forename: Gert
authors.initials: G
authors.lastname: Thijs
authors.forename: Yves
authors.initials: Y
authors.lastname: Moreau
authors.forename: Frank
authors.initials: F
authors.lastname: De Smet
authors.forename: Janick
authors.initials: J
authors.lastname: Mathys
authors.forename: Magali
authors.initials: M
authors.lastname: Lescot
authors.forename: Stephane
authors.initials: S
authors.lastname: Rombauts
authors.forename: Pierre
authors.initials: P
authors.lastname: Rouze
authors.forename: Bart
authors.initials: B
authors.lastname: De Moor
authors.forename: Kathleen
authors.initials: K
authors.lastname: Marchal
mesh_terms: D000465:Algorithms; D016000:Cluster Analysis; D019295:Computational Biology; D030541:Databases, Genetic; D020869:Gene Expression Profiling / Q000706:statistics & numerical data; D005810:Multigene Family; D020411:Oligonucleotide Array Sequence Analysis / Q000706:statistics & numerical data*; D012984:Software