[Determination of cortisol in plasma and 24-hour urine of patients with central serous chorioretinopathy].
OBJECTIVE
To study the cortisol levels in patients with central serous chorioretinopathy (CSCR).


METHODS
Endogenous cortisol levels in plasma and urine were determined in 44 patients with CSCR by radioimmunoassay and chromatography, and their results were compared with that of 41 controls.


RESULTS
In acute CSCR, the mean values of the plasma cortisol (296.53 +/- 77.03) ng/ml and 24-hour urine 17-hydroxysteroids (the major metabolite of cortisol metabolism) (12.08 +/- 4.82) mg/24 h revealed significantly higher values in the patient group (P < 0.05).


CONCLUSIONS
Increased levels of endogenous cortisol play a role in the development of CSCR.
Shang
Q
Q
Department of Ophthalmology, The Second Hospital, Hebei Medical University, Shijiazhuang 050000.
Liu
C
C
Wei
S
S
Shi
F
F
Li
Y
Y
Qiao
L
L
D015065:17-Hydroxycorticosteroids / Q000652:urine*; D000328:Adult; D002825:Chorioretinitis / Q000209:etiology / Q000378:metabolism*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged
D015065:17-Hydroxycorticosteroids; D006854:Hydrocortisone