Tensions in antibiotic prescribing: pitting social concerns against the interests of individual patients.
BACKGROUND
To reduce the prevalence of antibiotic-resistant bacteria in the community, physicians must optimize their use of antibiotics. However, optimal use from the perspective of the community (reserving newer agents for future use) is not always consistent with optimal use from the perspective of the individual patient (prescribing newer, broader agents).


OBJECTIVE
To identify preferred patterns of antibiotic prescribing for patients with community-acquired pneumonia (CAP), measure explicit attitudes toward antibiotics and antibiotic resistance, and determine the relationship between these prescribing patterns and attitudes.


METHODS
Cross-sectional anonymous mail survey.


METHODS
National random sample of 400 generalist physicians (general internal medicine and family practice) and 429 infectious diseases specialists.


METHODS
Rank ordering of antibiotic preferences for a hypothetical outpatient with CAP and reasons for antibiotic selection. Endorsement of attitudes regarding antibiotic prescribing decisions and resistance.


RESULTS
Both generalists and infectious diseases specialists were more likely to prefer newer, broader drugs for the treatment of CAP compared to older agents still recommended by national guidelines. Physicians rated the issue of contributing to antibiotic resistance lowest among 7 determinants of their choices.


CONCLUSIONS
Despite national guidelines and increasing public awareness, the public health concern of contributing to the problem of antibiotic resistance does not exert a strong impact on physician prescribing decisions for CAP. Future efforts to optimize antibiotic prescribing decisions will need to consider options for increasing the impact of public health issues on the patient-oriented decisions of individual physicians.
Metlay
Joshua P
JP
Philadelphia Veterans Affairs Medical Center, University of Pennsylvania School of Medicine, 712 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA. jmetlay@cceb.med.upenn.edu
Shea
Judy A
JA
Crossette
Linda B
LB
Asch
David A
DA
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001291:Attitude of Health Personnel; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000188:drug therapy; D003430:Cross-Sectional Studies; D003625:Data Collection; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D004352:Drug Resistance, Microbial; D004363:Drug Utilization / Q000706:statistics & numerical data* / Q000639:trends; D005194:Family Practice / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000188:drug therapy*; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D014481:United States
D000900:Anti-Bacterial Agents