[Comparative evaluation of a latex agglutination test, two Elisa tests and a Western blot test for the serodiagnosis of human trichinellosis].
Serology is a helpful test for the diagnosis of human trichinellosis because clinical signs of this disease (fever and myalgias) are non specific. A lot of techniques have been studied but very few are commercialized and have been comparatively evaluated. We report here the performances of 4 commercially available kits: two Elisa tests, one western blot test & one latex agglutination test. The specificity and sensitivity of the different tests were assayed on 60 sera from patients with a proven trichinellosis and on 70 controls. The four tests had a 100% sensitivity. The specificity was of 98.6% for the western blot, of 93% for the latex agglutination test and of 87 & 77% for the two Elisa tests. Cross reactions are mainly observed in patients with other helminthic infections.
Andiva
S
S
Laboratoire de parasitologie-mycologie, Hôpital Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris.
Yera
H
H
Haeghebaert
S
S
Tourte-Schaefer
C
C
Magnaval
J F
JF
Dupouy-Camet
J
J
D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007841:Latex Fixation Tests; D012680:Sensitivity and Specificity; D014235:Trichinellosis / Q000097:blood* / Q000175:diagnosis*