Effects of peroxidase on hyperlipidemia in mice.
To observe the effects of peroxidase on hyperlipidemia, mice were fed a diet high in cholesterol and fat. At the same time, the mice were given different-purity peroxidase (radish juice, crude radish peroxidase, and horseradish peroxidase), and their serum cholesterol, triglyceride, blood glucose, amylase, and esterase activities, and malondialdehyde in the mouse small intestines and livers, were tested after 15 days on the test diets. The results showed that peroxidase decreased the levels of total serum cholesterol, triglyceride, blood glucose, and lipid peroxidation in the small intestines and livers of hyperlipidemic mice. This suggests that peroxidase may be a contributing factor in the prevention of hyperlipidemia.
Wang
Linsong
L
Life Science College, Henan Normal University, Xinxiang, Henan, (453002), People's Republic of China. wangls2000@263.net
Wei
Liqin
L
Wang
Lin
L
Xu
Cunshuan
C
D000681:Amylases / Q000097:blood; D000818:Animals; D001628:Beverages; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D004950:Esterases / Q000097:blood; D005260:Female; D006735:Horseradish Peroxidase / Q000627:therapeutic use; D006949:Hyperlipidemias / Q000188:drug therapy*; D007421:Intestine, Small / Q000737:chemistry / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000737:chemistry / Q000378:metabolism; D008315:Malondialdehyde / Q000032:analysis; D051379:Mice; D009195:Peroxidase / Q000627:therapeutic use*; D014280:Triglycerides / Q000097:blood; D014675:Vegetables / Q000201:enzymology
D001786:Blood Glucose; D002791:Cholesterol, Dietary; D014280:Triglycerides; D008315:Malondialdehyde; D002784:Cholesterol; D006735:Horseradish Peroxidase; D009195:Peroxidase; D004950:Esterases; D000681:Amylases