title: Virulence factors of clinical isolates of Aeromonas caviae.
abstract: The mechanism of pathogenicity of 13 Aeromonas caviae strains isolated from fecal specimens of children with diarrhea was examined. Isolates possessed several virulence agents. Six of 13 isolates produced cholera-like toxin, all strains exhibited adhesive ability and secreted catecholate siderophores. Six isolates were able to grow in heat-inactivated serum. Production of hemolysins was not detected. The isolates had relatively high values of LD50 in a mouse model, which suggests that there is no linkage between pathogenicity to mice and the diarrheagenic ability of the isolates.
authors.affiliation: Department of Microbiology, Institute of Experimental Biology, A. Mickiewicz University, 617 01 Poznań, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Mokracka
authors.forename: S
authors.initials: S
authors.lastname: Krzymińska
authors.forename: E
authors.initials: E
authors.lastname: Szczuka
mesh_terms: D000333:Aeromonas / Q000254:growth & development / Q000302:isolation & purification / Q000472:pathogenicity*; D000818:Animals; D001422:Bacterial Adhesion; D001427:Bacterial Toxins / Q000096:biosynthesis / Q000276:immunology; D002648:Child; D002772:Cholera Toxin / Q000276:immunology; D003470:Culture Media; D003967:Diarrhea / Q000382:microbiology*; D004195:Disease Models, Animal; D005243:Feces / Q000382:microbiology; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D006801:Humans; D007583:Jejunum / Q000382:microbiology; D007928:Lethal Dose 50; D051379:Mice; D011817:Rabbits; D017262:Siderophores; D014774:Virulence
chemical_list: D001427:Bacterial Toxins; D003470:Culture Media; D017262:Siderophores; D002772:Cholera Toxin