title: Safety of lyophilized SAG2 oral rabies vaccine in collared lemmings.
abstract: Fifteen collared lemmings (Dicrostonyx groenlandicus) were exposed to a lyophilized oral rabies vaccine designed to immunize wild carnivore populations. No animals contracted rabies from the vaccine as determined by the absence of clinical signs after 37 days and lack of rabies virus in brain tissue determined by the fluorescent antibody (FA) test. These results suggest that collared lemmings would not contract rabies if they ingested this lyophilized vaccine in the wild during bait vaccination programs for arctic foxes (Alopex lagopus).
authors.affiliation: Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska 99775-7000, USA. ffehf@uaf.edu
authors.forename: Erich H
authors.initials: EH
authors.lastname: Follmann
authors.forename: Donald G
authors.initials: DG
authors.lastname: Ritter
authors.forename: Donald W
authors.initials: DW
authors.lastname: Hartbauer
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D003411:Arvicolinae; D001921:Brain / Q000821:virology; D005455:Fluorescent Antibody Technique; D011818:Rabies / Q000517:prevention & control / Q000662:veterinary*; D011819:Rabies Vaccines / Q000008:administration & dosage* / Q000276:immunology; D011820:Rabies virus / Q000276:immunology*; D012376:Rodent Diseases / Q000517:prevention & control*; D012449:Safety
chemical_list: D000914:Antibodies, Viral; D011819:Rabies Vaccines