title: Gonadal tumor with granulosa cell tumor features in an adult testis.
abstract: Granulosa cell tumor is almost exclusively an ovarian tumor. Rare cases of granulosa cell tumor have been reported involving the testes. We report a testicular gonadal stromal tumor with granulosa cell differentiation in a 54-year-old white man. The tumor was discovered by an ultrasound evaluation for left hydrocele. The patient was clinically asymptomatic. On frozen section, the initial impression was a malignant lymphoma. Final histology on the orchiectomy specimen showed a gonadal stromal tumor with granulosa cell features. Immunohistochemical studies excluded malignant lymphoma and germ cell tumors, consistent with a stromal tumor. This case report illustrates the challenges for the pathologist in making an accurate diagnosis in unusual testicular tumors.
authors.affiliation: Lilian and Henry M. Stratton-Hans Popper Department of Pathology, The Mount Sinai School of Medicine, The Mount Sinai Medical Center, New York, NY 10029, USA.
authors.forename: Beverly Y
authors.initials: BY
authors.lastname: Wang
authors.forename: David S
authors.initials: DS
authors.lastname: Rabinowitz
authors.forename: Roberto C
authors.initials: RC
authors.lastname: Granato
authors.forename: Pamela D
authors.initials: PD
authors.lastname: Unger
mesh_terms: D003951:Diagnostic Errors; D005629:Frozen Sections; D006106:Granulosa Cell Tumor / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology*