title: Hyperintense basal ganglia on T1-weighted magnetic resonance images in a patient with common variable immunodeficiency associated with elevated serum manganese.
abstract: The authors report on a 32-year-old man with common variable immunodeficiency and high signal intensity in basal ganglia on T1-weighted images. No signal alteration on T2-weighted and postcontrast images was observed. The patient had elevated levels of manganese in the serum. The authors conclude that the unusual hyperintensity in the basal ganglia area on T1-weighted images resulted from manganese deposition due to liver dysfunction.
authors.affiliation: Department of Neurology, Medical University of Lodz, 22 Kopcinskiego Street, 90-153 Lodz, Poland.
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Siger-Zajdel
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Selmaj
mesh_terms: D000328:Adult; D001479:Basal Ganglia / Q000473:pathology*; D017074:Common Variable Immunodeficiency / Q000097:blood / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008345:Manganese / Q000097:blood*
chemical_list: D008345:Manganese