title: [Cytochrome P450 2C19 gene polymorphism in four Chinese nationality populations].
abstract: OBJECTIVE
  To study the cytochrome P450 2C19(CYP2C19) gene polymorphism in 4 Chinese nationality populations.
  
  
  METHODS
  The genotypes of the unrelated Miao, Buyi, Tu and Dulong subjects were analyzed by polymerase chain reaction and restriction fragment length polymorphism (RFLP).
  
  
  RESULTS
  CYP2C19*2 allele frequencies were 0.291, 0.329, 0.315 and 0.349 in Miao, Buyi, Tu and Dulong population, respectively. The four populations were consistent with Hardy-Weinberg expectations (P>0.05).
  
  
  CONCLUSIONS
  The frequencies of CYP2C19*2 were in agreement with those of other published data on Asian, but were different from those data on European and African.
authors.affiliation: National Research Institute for Family Planning, Beijing, 100081 P. R. China. Zhsong2@hotmail.com
authors.forename: Song
authors.initials: S
authors.lastname: Zhang
authors.forename: Zhaowen
authors.initials: Z
authors.lastname: Dong
authors.forename: Li
authors.initials: L
authors.lastname: Tang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhou
authors.forename: Zhanpeng
authors.initials: Z
authors.lastname: Wu
mesh_terms: D001189:Aryl Hydrocarbon Hydroxylases; D044466:Asian People / Q000235:genetics; D044383:Black People / Q000235:genetics; D002681:China / Q000208:ethnology; D065731:Cytochrome P-450 CYP2C19; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D006899:Mixed Function Oxygenases / Q000235:genetics*; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D044465:White People / Q000235:genetics
chemical_list: D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19