Angiotropic large cell lymphoma with imaging characteristics of CNS vasculitis.
This report documents a case of angiotropic large cell lymphoma (ALCL) with imaging characteristics of CNS vasculitis. A 47-year-old man was unresponsive after a 5-month progression of neurologic deterioration and intermittent fevers. MR imaging revealed multiple areas of abnormally increased T2 signal intensity in the cerebral cortex and subcortical white matter. Despite corticosteroid treatment for presumed CNS vasculitis, the patient died. Necropsy revealed a diffuse intravascular malignant mononuclear proliferation consistent with ALCL.
Song
Debbie K
DK
Department of Neurosurgery, University of Michigan Medical Center, Kresge III, 200 Zina Pitcher Place, Ann Arbor, MI 48109, USA.
Boulis
Nicholas M
NM
McKeever
Paul E
PE
Quint
Douglas J
DJ
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002490:Central Nervous System / Q000098:blood supply*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D017809:Fatal Outcome; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D019043:Vascular Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014657:Vasculitis / Q000175:diagnosis*
D000893:Anti-Inflammatory Agents; D011241:Prednisone