title: Circe effect versus enzyme preorganization: what can be learned from the structure of the most proficient enzyme?
authors.affiliation: Department of Chemistry, University of Southern California, 3620 McClintock Av. SGM #418, Los Angeles, CA 90089-1062, USA. warshel@usc.edu
authors.forename: A
authors.initials: A
authors.lastname: Warshel
authors.forename: J
authors.initials: J
authors.lastname: Florián
authors.forename: M
authors.initials: M
authors.lastname: Strajbl
authors.forename: J
authors.initials: J
authors.lastname: Villà
mesh_terms: D001665:Binding Sites; D004563:Electrochemistry; D007700:Kinetics; D008958:Models, Molecular; D009964:Orotidine-5'-Phosphate Decarboxylase / Q000737:chemistry*; D011487:Protein Conformation
chemical_list: D009964:Orotidine-5'-Phosphate Decarboxylase