title: [Primitive neuroectodermal tumor of bone and soft tissue].
abstract: OBJECTIVE
  To study the pathological characteristics of primitive neuroectodermal tumor (PNET) of bone and soft tissue.
  
  
  METHODS
  Five patients with bone and soft tissue of PNET (2 men and 3 women) were studied by light microscope and immunohistochemistry. The age of the patients was 18, 18, 43, 14, 32 years and the primary sites of involvement were the ilium (n = 2), axillary fossa (n = 1), condyle of femur (n = 1), and diploe (n = 1). X-ray films showed bone osteolytic destruction, and no periosteal reaction or calcification. Surgery was performed in the patients.
  
  
  RESULTS
  All patients received combined chemotherapy and 3 received radiotherapy. Three patients died of metastatic tumor of lung 20, 13, and 5 months after invasion. 1 patient metastatic tumor of lung 20 months after invasion, and 1 patient bone extensive metastasis 1.5 months after surgery.
  
  
  CONCLUSIONS
  The treatment of PNET of bone and soft tissue awaits further study.
authors.affiliation: Department of Orthopaedics, First Hospital of Beijing Medical University, Beijing 100034.
authors.forename: Z
authors.initials: Z
authors.lastname: Fang
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Na
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: X
authors.initials: X
authors.lastname: Shi
authors.forename: Z
authors.initials: Z
authors.lastname: Xing
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D018242:Neuroectodermal Tumors, Primitive / Q000473:pathology* / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000628:therapy