Frequency of isolation of Staphylococcus lugdunensis in consecutive urine cultures and relationship to urinary tract infection.
Recent reports associate Staphylococcus lugdunensis with severe infection in humans. The frequency of this microorganism in urine cultures is unknown. Five hundred isolates of coagulase-negative staphylococci (CoNS) were recovered from 4,652 consecutive urine specimens submitted for culture to the Mayo Clinic Microbiology Laboratory. Thirty-one (6%) of 500 isolates of CoNS were identified as S. lugdunensis. In no case was S. lugdunensis isolated in pure culture; 29 (94%) of 31 S. lugdunensis isolates were part of mixed nonpathogenic flora. Medical records were reviewed for 30 of the 31 patients from whom these 31 isolates were isolated. Twenty-one (70%) of the 30 evaluable patients were not treated with antibiotics; the remaining 9 (30%) of 30 patients were treated with antibiotics that may be effective against S. lugdunensis. S. lugdunensis may be an unrecognized yet infrequent cause of urinary tract infection.
Haile
D T
DT
Mayo Medical School, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
Hughes
J
J
Vetter
E
E
Kohner
P
P
Snyder
R
R
Patel
R
R
Cockerill
F R
FR
D000368:Aged; D001431:Bacteriological Techniques; D003030:Coagulase / Q000378:metabolism; D003470:Culture Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology*; D013210:Staphylococcus / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity*; D014552:Urinary Tract Infections / Q000382:microbiology*; D014556:Urine / Q000382:microbiology*
D003030:Coagulase; D003470:Culture Media