title: Granulocyte colony stimulating factor treatment for delayed recovery of ticlopidine-related neutropenia.
abstract: We describe the case of a patient who developed neutropenia associated with sepsis and endophthalmitis after ticlopidine therapy for coronary stenting. The neutropenia did not resolve until granulocyte colony stimulating factor (G-CSF) was given. This uncommon case brings to attention the need for the immediate use of G-CSF in patients with delayed recovery from drug-related neutropenia and severe infection.
authors.affiliation: Department of Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan.
authors.forename: M J
authors.initials: MJ
authors.lastname: Hung
authors.forename: C H
authors.initials: CH
authors.lastname: Wang
authors.forename: W J
authors.initials: WJ
authors.lastname: Cherng
mesh_terms: D009877:Endophthalmitis / Q000150:complications; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000139:chemically induced* / Q000188:drug therapy*; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D018805:Sepsis / Q000150:complications; D013988:Ticlopidine / Q000009:adverse effects*
chemical_list: D010975:Platelet Aggregation Inhibitors; D016179:Granulocyte Colony-Stimulating Factor; D013988:Ticlopidine