Determination of caffeine in pharmaceutical preparations by the linear absorbances method.
In this work a fast Linear Absorbance Method for the determination of caffeine in pharmaceutical preparations in the presence of paracetamol or acetylsalicylic acid is presented. The determination of acetylsalicylic acid or paracetamol is also possible by means of a tabulated parameter fB, which values are included in this paper. The method avoids the use of separation steps or multicalibration methods. The determination was carried out in commercial preparations with good results.
Pascual-Martí
M C
MC
Departamento de Química Analítica, Facultad de Químicas, Universitat de Valencia, Burjassot, Valencia, Spain. Carmen.Pascual@uv.es
Llobat-Estellés
M
M
Roig-Marco
M I
MI
D000082:Acetaminophen / Q000032:analysis; D000465:Algorithms; D001241:Aspirin / Q000032:analysis; D002110:Caffeine / Q000032:analysis*; D002138:Calibration; D004338:Drug Combinations; D013056:Spectrophotometry, Ultraviolet
D004338:Drug Combinations; D000082:Acetaminophen; D002110:Caffeine; D001241:Aspirin