Increased fecal IgE among infants in a rural community of Egypt: an analysis of associated risk factors.
Newborns in rural Bilbeis, Egypt were followed to 1-year of age to document the incidence and risk factors associated with the development of fecal IgE. Factors associated with increased fecal IgE included infants aged 3-6 months (relative risk (RR) = 3.28, 95 per cent confidence intervals (CI) = 1.03-13.60, p < 0.05) and mother being vaccinated antenatally (RR = 2.17, CI - 1.01-4.61, p < 0.05). Decreased fecal IgE was observed with consumption of rice (RR = 0.37, CI = 0.12-0.94, p < 0.05), biscuits (RR = 0.43, CI = 0.15-0.99, p < 0.05), potatoes (RR = 0.39, CI = 0.11-0.98, p < 0.05), and fruits and vegetables (RR = 0.20, CI = 0.02-0.80, p < 0.05). After multivariate adjustment, increased risk was observed with consumption of milk pudding (RR = 7.48, CI = 1.54-36.20, p < 0.05) and wet-nursed infants (RR = 2.77, CI = 1.17-6.54, p < 0.05). Infants who were completely breastfed (RR = 0.13, CI = 0.02-0.68, p < 0.05) and infants' family owning a television set (RR = 0.29, CI = 0.12-0.67, p < 0.05) were less likely to develop fecal IgE. Our findings indicate that prelacteal feeding with certain foods, early supplementation of breastfeeding, and sociodemographic factors are associated with increased fecal IgE.
Mahmud
M A
MA
University of Texas School of Public Health/Medical School, Houston, USA.
Marshall
G D
GD
Hossain
M M
MM
Huang
D B
DB
Habib
M
M
DuPont
H L
HL
D000704:Analysis of Variance; D001942:Breast Feeding; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D003906:Developing Countries; D003968:Diarrhea, Infantile / Q000175:diagnosis* / Q000453:epidemiology*; D004534:Egypt / Q000453:epidemiology; D005243:Feces / Q000737:chemistry; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011159:Population Surveillance; D016016:Proportional Hazards Models; D012307:Risk Factors; D012424:Rural Population; D012720:Severity of Illness Index; D012959:Socioeconomic Factors
D007073:Immunoglobulin E