Dragon Promoter Finder: recognition of vertebrate RNA polymerase II promoters.
Dragon Promoter Finder (DPF) locates RNA polymerase II promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN). Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs.
Bajic
Vladimir B
VB
BIC-KRDL, Kent Ridge Digital Laboratories, 21, Heng Mui Keng Terrace, Singapore 119613. bajicv@krdl.org.sg
Seah
Seng Hong
SH
Chong
Allen
A
Zhang
Guanglan
G
Koh
Judice L Y
JL
Brusic
Vladimir
V
D000465:Algorithms; D019295:Computational Biology; D030561:Databases, Nucleic Acid; D005091:Exons; D006801:Humans; D007438:Introns; D016571:Neural Networks, Computer; D011401:Promoter Regions, Genetic; D012319:RNA Polymerase II / Q000235:genetics*; D012984:Software
D012319:RNA Polymerase II