Levodopa-induced ocular dyskinesias in Parkinson's disease.
Levodopa-induced ocular dyskinesias are very uncommon. Usually they occur simultaneously with limb peak-dose choreatic dyskinesias. We report on a patient with leftward and upward deviations of gaze during the peak effect of levodopa, and hypothesize that a severe dopaminergic denervation in the caudate nucleus is needed for the appearance of these levodopa-induce ocular dyskinesias.
Linazasoro
Gurutz
G
Centro de Neurología y Neurocirugía funcional Clínica Quirón San Sebastián, Spain. neurotax@jet.es
Van Blercom
Nadege
N
Lasa
Asier
A
Indakoetxea
Begoña
B
Ruiz
Javier
J
D000978:Antiparkinson Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015835:Ocular Motility Disorders / Q000139:chemically induced* / Q000175:diagnosis; D010300:Parkinson Disease / Q000188:drug therapy*
D000978:Antiparkinson Agents; D007980:Levodopa