title: Crystal structure of calpain and insights into Ca(2+)-dependent activation.
authors.affiliation: Department of Biochemistry, Queen's University, Protein Engineering Network of Centres of Excellence, Kingston, ON, Canada.
authors.forename: Zongchao
authors.initials: Z
authors.lastname: Jia
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Hosfield
authors.forename: Peter L
authors.initials: PL
authors.lastname: Davies
authors.forename: John S
authors.initials: JS
authors.lastname: Elce
mesh_terms: D000818:Animals; D001665:Binding Sites; D002118:Calcium / Q000378:metabolism*; D002154:Calpain / Q000737:chemistry* / Q000378:metabolism*; D018360:Crystallography, X-Ray; D006023:Glycoproteins / Q000737:chemistry / Q000378:metabolism; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D015394:Molecular Structure; D017434:Protein Structure, Tertiary; D021122:Protein Subunits; D051381:Rats
chemical_list: D006023:Glycoproteins; D008565:Membrane Proteins; D021122:Protein Subunits; C410340:calpain activator; C039304:calpain inhibitors; D002154:Calpain; C449000:m-calpain; D002118:Calcium