[Subpopulations of TIL in renal cell carcinoma and their clinical significance].
OBJECTIVE
To study the relationship between tumor-infiltrating lymphocytes (TIL) and the prognosis of patients with renal cell carcinoma.


METHODS
Immunohistological chemistry method was employed to semiquantitatively assess the expression of TIL and its subpopulations. The prognostic values of various TIL subpopulations were also evaluated.


RESULTS
T-lymphocyte was the main component of TIL, B-lymphocyte, monocyte, and nature killer (NK) cells were also presented but in relatively small numbers. T-lymphocyte was strongly correlated to the survival probability, but this correlation was not observed between the host survival and TIL or other subpopulations.


CONCLUSIONS
T-lymphocyte can represent the host immunological status and can be used to judge the prognosis of patients with renal cell carcinoma.
Li
Y
Y
Department of Urology, People's Hospital, Beijing Medical University, Beijing 100044.
Hou
S
S
Zhang
X
X
Zhang
G
G
Zhu
J
J
Wang
X
X
D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000737:chemistry; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000276:immunology* / Q000378:metabolism; D016246:Lymphocytes, Tumor-Infiltrating / Q000737:chemistry / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013601:T-Lymphocytes / Q000737:chemistry