title: [Clinical study of sodium hyaluronate in supplementary treatment of comminuted fracture of ankle].
abstract: OBJECTIVE
  To investigate the effects of sodium hyaluronate in supplementary treatment of comminuted fracture of ankle.
  
  
  METHODS
  Thirty-seven patients suffered from comminuted fracture of ankle were operated for restoration by routing methods, and received 2 ml of sodium hyaluronate injection intra-articularly before the closure of incision. The ankle was fixed and given the second intra-articular injection on the 3rd day after operation. Then, the patients were given sodium hyaluronate injection intra-articularly at a week intervals till the paste was removed after 4 weeks. All patients were followed up. The clinical results were evaluated by measuring the symptoms of pain, and the function of walking and other daily living activities.
  
  
  RESULTS
  All the patients were followed up for 6 to 27 months, among them, 30 patients were cured completely without any symptoms, the ankle function for walking and daily living activities was normal, 6 patients felt pain with violent activity or walking exceeding 1 km, one patient suffered from comminuted fracture with compressed depression was not improved due to his ankle being not restored properly.
  
  
  CONCLUSIONS
  Intra-articular injection of sodium hyaluronate is an effective supplementary treatment for comminuted fracture of ankle.
authors.affiliation: Department of Orthopedics, Xinjiang Builders' Hospital, Ulumuqi Xinjiang, P. R. China 830002.
authors.forename: Cheng-wei
authors.initials: CW
authors.lastname: Wang
authors.forename: Li-hua
authors.initials: LH
authors.lastname: Gao
authors.forename: Xiao-yue
authors.initials: XY
authors.lastname: Jin
authors.forename: Ping-bo
authors.initials: PB
authors.lastname: Chen
authors.forename: Guang-ming
authors.initials: GM
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D016512:Ankle Injuries / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D018460:Fractures, Comminuted / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D007270:Injections, Intra-Articular; D008297:Male; D008875:Middle Aged
chemical_list: D006820:Hyaluronic Acid