title: Radiofrequency ablation for unresectable hepatic tumors.
abstract: BACKGROUND
  Radiofrequency ablation (RFA) is a relatively new treatment for unresectable hepatic tumors. The purpose of this analysis was to examine the frequency of complications and local recurrence associated with RFA.
  
  
  METHODS
  Patients who underwent RFA of hepatic tumors with curative intent were included in this study. At laparotomy, RFA was performed using intraoperative ultrasound guidance. Computed tomography scans were obtained in the immediate postoperative period and every 3 to 6 months thereafter.
  
  
  RESULTS
  Forty patients underwent RFA for 122 hepatic tumors. Thirty-one patients had metastatic lesions from colorectal cancer; 9 had other liver tumors. Complications occurred in 8 patients. With 9.5 months median follow-up, 6 patients had local recurrence of their ablated tumors.
  
  
  CONCLUSIONS
  Our initial experience shows that RFA can effectively eradicate unresectable hepatic tumors. The rate and severity of complications appear acceptable. However, further study is necessary to assess long-term recurrence rates and effect on overall survival.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, University of Louisville, Louisville, KY 40202, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Wong
authors.forename: M J
authors.initials: MJ
authors.lastname: Edwards
authors.forename: C
authors.initials: C
authors.lastname: Chao
authors.forename: D
authors.initials: D
authors.lastname: Simpson
authors.forename: K M
authors.initials: KM
authors.lastname: McMasters
mesh_terms: D017115:Catheter Ablation; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications; D016896:Treatment Outcome