Accelerating code to function: sizing up the protein production line.
High-throughput biology has been pioneered by genomics through the application of robotics to expedite DNA-sequencing projects. Advances in high-throughput protein methods are needed to drive the protein production line for high-throughput structural and functional analysis of newly discovered genes. This will require the development and application of a variety of recombinant-protein expression systems to produce the diversity of proteins from both humans and model organisms.
Gilbert
Michele
M
Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, California 94550, USA.
Albala
Joanna S
JS
D000818:Animals; D001331:Automation; D016367:Baculoviridae / Q000378:metabolism; D019976:Cloning, Organism / Q000379:methods; D006801:Humans; D014176:Protein Biosynthesis; D011506:Proteins / Q000032:analysis* / Q000235:genetics; D020543:Proteome / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics; D011994:Recombinant Proteins / Q000032:analysis / Q000096:biosynthesis
D011506:Proteins; D020543:Proteome; D011994:Recombinant Proteins