Unilateral central retinal artery occlusion following intravenous streptokinase.
A 38-year-old male with acute myocardial infraction who had received streptokinase presented with acute painless diminution of vision in the left eye. Examination revealed features of central retinal artery occlusion on the left side with vision of perception of light. Treatment in the form of systemic and local intraocular pressure lowering agents, retrobulbar xanthinol nicotinate and systemic injection of B-complex resulted in improvement of vision to counting fingers up to one meter. In this case thrombolytic therapy itself led to embolism into the left central retinal artery resulting in its occlusion and eventually optic atrophy and blindness.
Potdar
N A
NA
Department of Ophthalmology, B.Y.L. Nair Hospital, Mumbai - 400 008, India.
Shinde
C A
CA
Murthy
G G
GG
Ingole
A B
AB
D000328:Adult; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy*; D015356:Retinal Artery Occlusion / Q000139:chemically induced*; D013300:Streptokinase / Q000008:administration & dosage* / Q000009:adverse effects* / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D013300:Streptokinase