Rejuvenating views of the ageing process.
Commonly held assumptions about the ageing process have guided and directed research in this important area over many years. Recent evidence, however, from disciplines as diverse as molecular genetics, clinical epidemiology and demography, provide a direct challenge to the validity of many of these assumptions. So, the time is ripe to re-examine these assumptions about the ageing process and to rethink the scientific foundations of the field.
Helfand
Stephen L
SL
School of Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, Connecticut 06030, USA. shelfand@neuron.uchc.edu
Inouye
Sharon K
SK
D000375:Aging / Q000235:genetics* / Q000502:physiology; D000818:Animals; D015870:Gene Expression; D006706:Homeostasis; D006801:Humans; D009154:Mutation; D011157:Population Dynamics