title: Inverse planning and intensity-modulated radiotherapy in patients with prostate cancer.
abstract: Inverse planning and IMRT are methods with the potential to improve substantially clinical results in radiotherapy of prostate cancer. Available early clinical data demonstrate the feasibility and safety of high-dose IMRT for patients with localized prostate cancer and provide a proof-of-principle that this method improves dose conformality relative to tumor coverage and exposure to normal tissues.
authors.affiliation: Radiologische Klinik, Universitätsklinikum Heidelberg, Deutsches Krebsforschungszentrum (dkfz), Heidelberg, Deutschland. j.debus@dkfz.de
authors.forename: Jürgen
authors.initials: J
authors.lastname: Debus
authors.forename: Dietmar
authors.initials: D
authors.lastname: Zierhut
authors.forename: Bernd
authors.initials: B
authors.lastname: Didinger
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Schlegel
authors.forename: Michael
authors.initials: M
authors.lastname: Wannenmacher
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000379:methods*