title: Levels of circulating intercellular adhesion molecule-1 in patients with Behçet's disease.
abstract: The purpose of this study was to investigate the possible relationship between circulating intercellular adhesion molecule-1 (cICAM-1) plasma levels and Behçet's disease. Plasma levels of cICAM-1 were measured in 44 patients with Behçet's disease and in 30 healthy controls. cICAM-1 levels were higher in patients with Behçet's disease than in the controls (P=0.001). The difference was more marked between patients with active Behçet's disease and controls (P < 0.001). cICAM-1 levels were also higher in patients with active Behçet's disease than in those with inactive disease (P<0.001). cICAM-1 seems to be related to disease activity in Behçet's disease. It may be useful in assessing disease activity in Behçet's disease, as well as in monitoring response to treatment.
authors.affiliation: Department of Internal Medicine, Ankara, Turkey. ksaglam@gata.edu.tr
authors.forename: Kenan
authors.initials: K
authors.lastname: Saglam
authors.forename: M Ilker
authors.initials: MI
authors.lastname: Yilmaz
authors.forename: Ayse
authors.initials: A
authors.lastname: Saglam
authors.forename: Mete
authors.initials: M
authors.lastname: Ulgey
authors.forename: Fatih
authors.initials: F
authors.lastname: Bulucu
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Baykal
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000097:blood* / Q000503:physiopathology*; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D015331:Cohort Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood*; D008297:Male; D012016:Reference Values; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D018799:Intercellular Adhesion Molecule-1