[Effect of escharectomy during burn shock stage on stress response].
OBJECTIVE
To investigate changes in hormones of plasma and the effect of escharectomy during burn shock stage on early stress response after burn.


METHODS
Sixteen male minipigs were subjected to a 35% TBSA III degree burn injury. The burned minipigs were randomly divided into two groups: escharectomy during burn shock stage group (S group) and escharectomy group after burn shock stage (N group). The sequential changes in plasma levels of insulin, glucagon, cortisol, GH, IGF-I, albumin were analyzed.


RESULTS
The serum concentration of insulin, glucagon, cortisol increased to some degree, whereas the serum concentration of GH, IGF-I decreased obviously after burn. As compared with the N group, no significant difference in the serum concentration of glucagon, cortisol, GH, IGF-I, was observed.


CONCLUSIONS
Escharectomy during burn shock stage could not aggravate stress response after burn.
Hao
D
D
Burn Institute, 304th Hospital, People's Liberation Army, Beijing 100037.
Guo
Z
Z
Chai
J
J
He
L
L
Sheng
Z
Z
D000818:Animals; D002056:Burns / Q000097:blood* / Q000601:surgery; D005934:Glucagon / Q000097:blood; D013006:Growth Hormone / Q000097:blood*; D007328:Insulin / Q000097:blood; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008297:Male; D011897:Random Allocation; D012774:Shock, Traumatic / Q000097:blood* / Q000601:surgery; D016038:Skin Transplantation; D013312:Stress, Physiological / Q000097:blood*; D013552:Swine; D013556:Swine, Miniature
D007328:Insulin; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone; D005934:Glucagon