title: [Locus Delta in the Notch signaling system: organization and pleiotropic function during Drosophila development].
abstract: Delta locus is the important component of the Delta-Notch signaling system implicating in a general mechanism of local cell signaling. Delta and Notch encode the evolutionary conserved cell surface proteins that interact and function as ligand (DELTA) and receptor (NOTCH) in a wide variety of cell fate specification events during oogenesis, embryogenesis and metamorphosis.
authors.forename: I S
authors.initials: IS
authors.lastname: Gubenko
mesh_terms: D000818:Animals; D004330:Drosophila / Q000235:genetics* / Q000254:growth & development; D029721:Drosophila Proteins; D019143:Evolution, Molecular; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000502:physiology; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins / Q000502:physiology*; D011956:Receptors, Cell Surface / Q000378:metabolism; D051880:Receptors, Notch; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; C497759:N protein, Drosophila; D011956:Receptors, Cell Surface; D051880:Receptors, Notch; C064045:delta protein