Outbreak of nosocomial sepsis and pneumonia in a newborn intensive care unit by multiresistant extended-spectrum beta-lactamase-producing Klebsiella pneumoniae: high impact on mortality.
We describe a case-control study of a small outbreak of nosocomial sepsis and pneumonia with high mortality due to clonal dissemination of a multiresistant Klebsiella pneumoniae in the neonatal intensive care unit of a Mexican institution. Our study helped to change nosocomial infection control policy in this hospital.
Martinez-Aguilar
G
G
Unidad de Investigación Médica en Epidemiología Clínica, Hospital Regional de Zona No. 1, Insituto Mexicano del Seguro Social, Durango.
Alpuche-Aranda
C M
CM
Anaya
C
C
Alcantar-Curiel
D
D
Gayosso
C
C
Daza
C
C
Mijares
C
C
Tinoco
J C
JC
Santos
J I
JI
D016022:Case-Control Studies; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality*; D004196:Disease Outbreaks; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D007710:Klebsiella Infections / Q000188:drug therapy / Q000453:epidemiology / Q000401:mortality*; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000302:isolation & purification*; D018410:Pneumonia, Bacterial / Q000188:drug therapy / Q000453:epidemiology / Q000401:mortality*; D018805:Sepsis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality*; D001618:beta-Lactamases / Q000096:biosynthesis*
D001618:beta-Lactamases