title: Endocrine disruption caused by two common pollutants at "acceptable" concentrations.
abstract: This report focuses on the impact of low concentrations of two purported endocrine-disrupting xenobiotic compounds, nonylphenol and methoxychlor, on two freshwater teleosts of the genus Xiphophorus, X. maculatus, commonly known as the platyfish, and X. helleri, commonly known as the swordtail. Nonylphenol exposure increased mortality rates, elicited stress behaviors, decreased body weight and significantly hampered gonadal development and reproductive function. Methoxychlor exposure elicited stress behaviors, decreased body weight and significantly retarded sexual development. This report demonstrates that, even at "acceptable" concentrations, these compounds pose a serious threat to our aquatic ecosystems.
authors.affiliation: State University of New York at Farmingdale, Farmingdale, NY 11735, USA.
authors.forename: Lucia
authors.initials: L
authors.lastname: Magliulo
authors.forename: Martin P
authors.initials: MP
authors.lastname: Schreibman
authors.forename: Jessica
authors.initials: J
authors.lastname: Cepriano
authors.forename: Jacquline
authors.initials: J
authors.lastname: Ling
mesh_terms: D000818:Animals; D003532:Cyprinodontiformes / Q000254:growth & development*; D004702:Endocrine Glands / Q000187:drug effects* / Q000473:pathology; D005260:Female; D007306:Insecticides / Q000633:toxicity; D008297:Male; D008731:Methoxychlor / Q000633:toxicity; D010636:Phenols / Q000633:toxicity; D012098:Reproduction / Q000187:drug effects*; D012741:Sexual Maturation / Q000187:drug effects*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D007306:Insecticides; D010636:Phenols; D014874:Water Pollutants, Chemical; C025256:nonylphenol; D008731:Methoxychlor