title: Dragon Promoter Finder: recognition of vertebrate RNA polymerase II promoters.
abstract: Dragon Promoter Finder (DPF) locates RNA polymerase II promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN). Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs.
authors.affiliation: BIC-KRDL, Kent Ridge Digital Laboratories, 21, Heng Mui Keng Terrace, Singapore 119613. bajicv@krdl.org.sg
authors.forename: Vladimir B
authors.initials: VB
authors.lastname: Bajic
authors.forename: Seng Hong
authors.initials: SH
authors.lastname: Seah
authors.forename: Allen
authors.initials: A
authors.lastname: Chong
authors.forename: Guanglan
authors.initials: G
authors.lastname: Zhang
authors.forename: Judice L Y
authors.initials: JL
authors.lastname: Koh
authors.forename: Vladimir
authors.initials: V
authors.lastname: Brusic
mesh_terms: D000465:Algorithms; D019295:Computational Biology; D030561:Databases, Nucleic Acid; D005091:Exons; D006801:Humans; D007438:Introns; D016571:Neural Networks, Computer; D011401:Promoter Regions, Genetic; D012319:RNA Polymerase II / Q000235:genetics*; D012984:Software
chemical_list: D012319:RNA Polymerase II