title: Quantification of interpoint topographic correlations of threshold values in glaucomatous visual fields.
abstract: OBJECTIVE
  The authors sought to quantify neighboring and distant interpoint correlations of threshold values within the visual field in patients with glaucoma.
  
  
  METHODS
  Visual fields of patients with confirmed or suspected glaucoma were analyzed (n = 255). One eye per patient was included. Patients were examined using the 32 program of the Octopus 1-2-3. Linear regression analysis among each of the locations and the rest of the points of the visual field was performed, and the correlation coefficient was calculated. The degree of correlation was categorized as high (r(2) > 0.66), moderate (0.66 > or = r(2) > 0.33), or low (r(2) < or = 0.33). The standard error of threshold estimation was calculated.
  
  
  RESULTS
  Most locations of the visual field had high and moderate correlations with neighboring points and with distant locations corresponding to the same nerve fiber bundle. Locations of the visual field had low correlations with those of the opposite hemifield, with the exception of locations temporal to the blind spot. The standard error of threshold estimation increased from 0.6 to 0.9 dB with an r(2) reduction of 0.1.
  
  
  CONCLUSIONS
  Locations of the visual field have highest interpoint correlation with neighboring points and with distant points in areas corresponding to the distribution of the retinal nerve fiber layer. The quantification of interpoint correlations may be useful in the design and interpretation of visual field tests in patients with glaucoma.
authors.affiliation: Ophthalmology Department, University of La Laguna, Tenerife, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: González de la Rosa
authors.forename: Marta
authors.initials: M
authors.lastname: González-Hernández
authors.forename: Maximino
authors.initials: M
authors.lastname: Abraldes
authors.forename: Augusto
authors.initials: A
authors.lastname: Azuara-Blanco
mesh_terms: D005260:Female; D005901:Glaucoma / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis / Q000503:physiopathology; D012684:Sensory Thresholds; D014786:Vision Disorders / Q000175:diagnosis* / Q000503:physiopathology; D058609:Visual Field Tests / Q000379:methods; D014794:Visual Fields