title: Computerized calculation of biological potency: presentation of the interactive computer program "POTENCY" (assays: "2 + 2" doses, "3 + 3" doses, "twin cross-over assay" and "probit analysis" ("2 + 2" doses).
abstract: Paper presents the interactive computer program "POTENCY" written in BASIC program language, based on the algorithm for classifying biological assays using the assays: "2 + 2" doses, "3 + 3" doses, twin cross-over assay and probit analysis ("2 + 2" doses) described in Yugoslav Pharmacopeia (Ph. Jug. IV). The program execution is presented by assay examples of biological potency calculation described in European Pharmacopeia (Eur. Ph. 1997). The assay-examples have simultaneously been the measure of program execution correctness.
authors.affiliation: Pharmaceutical Factory GALENIKA a.d., Quality Control Center, Dept. Biological Control, Beograd-Zemun, Yugoslavia.
authors.forename: M B
authors.initials: MB
authors.lastname: Arambasić
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D018592:Cross-Over Studies; D004305:Dose-Response Relationship, Drug; D008954:Models, Biological; D015233:Models, Statistical; D010600:Pharmacology; D018401:Sample Size