The skin-lightening effects of artocarpin on UVB-induced pigmentation.
This study was conducted to evaluate the effects of the prenylated flavonol artocarpin from the heartwood of Artocarpus incisus on ultraviolet (UV)-induced hyperpigmentation of guinea pig skin. An efficient lightening effect was observed following topical application of artocarpin to UV-stimulated hyperpigmented dorsal skins of brownish guinea pigs.
Shimizu
Kuniyoshi
K
Department of Forestry and Forest Products Science, Faculty of Agriculture, Kyushu University, Fukuoka, Japan. shimizu@agr.kyushu-u.ac.jp
Kondo
Ryuichiro
R
Sakai
Kokki
K
Takeda
Norio
N
Nagahata
Tetsuji
T
D000818:Animals; D001104:Arbutin / Q000494:pharmacology; D002352:Carrier Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006168:Guinea Pigs; D037102:Lectins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D037241:Mannose-Binding Lectins; D008543:Melanins / Q000378:metabolism* / Q000528:radiation effects; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000378:metabolism; D029586:Moraceae; D037121:Plant Lectins; D011753:Pyrones / Q000494:pharmacology; D012880:Skin Pigmentation / Q000187:drug effects* / Q000528:radiation effects; D014466:Ultraviolet Rays
D002352:Carrier Proteins; D037102:Lectins; D037241:Mannose-Binding Lectins; D008543:Melanins; D037121:Plant Lectins; D011753:Pyrones; C090683:artocarpin lectin; C011890:kojic acid; D001104:Arbutin; D014442:Monophenol Monooxygenase