title: CD45 exon 4 point mutation does not confer susceptibility to type 1 diabetes mellitus or Graves' disease.
abstract: A point mutation in the leukocyte common antigen (CD45, C-->G77, exon 4) was investigated in patients with type 1 diabetes (IDDM), patients with Graves' disease and controls. The distribution did not differ significantly between patients and controls. This CD45 variant does not therefore confer susceptibility to either IDDM or Graves' disease.
authors.affiliation: Medical Department 1, Division of Endocrinology, Centre of Internal Medicine, Johann Wolfgang Goethe University Hospital, Theodor-Stern-Kai 7, D-60590 Frankfurt/Main, Germany.
authors.forename: J P
authors.initials: JP
authors.lastname: Wood
authors.forename: K
authors.initials: K
authors.lastname: Bieda
authors.forename: M
authors.initials: M
authors.lastname: Segni
authors.forename: J
authors.initials: J
authors.lastname: Herwig
authors.forename: M
authors.initials: M
authors.lastname: Krause
authors.forename: K H
authors.initials: KH
authors.lastname: Usadel
authors.forename: K
authors.initials: K
authors.lastname: Badenhoop
mesh_terms: D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D005091:Exons; D020022:Genetic Predisposition to Disease; D006111:Graves Disease / Q000235:genetics*; D006801:Humans; D017493:Leukocyte Common Antigens / Q000235:genetics*; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1
chemical_list: D017493:Leukocyte Common Antigens; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1