Facile palladium(0)-catalyzed ring expansion reactions of hydroxy methoxyallenyl cyclic compounds via hydropalladation.
Palladium(0)-catalyzed one-atom ring expansion of various hydroxy methoxyallenyl compounds has been achieved in excellent yields without the use of aryl halides. Hydroxy methoxyallenylisoindolinones, -indanones, and -phthalans have been readily converted to the corresponding isoquinolones, naphthoquinones, and isochromanones in the presence of P(o-tolyl)(3).
Nagao
Yoshimitsu
Y
Faculty of Pharmaceutical Sciences, The University of Tokushima, Sho-machi, Tokushima 770-8505, Japan. ynagao@ph2.tokushima-u.ac.jp
Ueki
Akiharu
A
Asano
Kazunori
K
Tanaka
Satoru
S
Sano
Shigeki
S
Shiro
Motoo
M