[MR angiography and flow measurement in coronary arteries and coronary bypass grafts].
Better MR image quality of coronary arteries and coronary grafts is the product of increased spatial and temporal resolution. Breathing artifacts could be reduced by implementing breath-holding and navigator techniques. With these developments normal coronary arteries can often be imaged reliably. Several trials have been performed in order to test the reliability of MR angiography to detect coronary artery stenosis. But up to now, sensitivity and specificity have proven to be too low to introduce these techniques in clinical routine. The patency of coronary grafts can be detected reliably using different MR techniques. Coronary flow reserve can be measured using the MR phase contrast technique. This noninvasive approach was tested in diseased coronary arteries and in graft stenoses. A reduced MR coronary flow reserve corresponded to reduced flow reserve measured invasively. Measurement of MR flow reserve in normal and diseased coronary grafts revealed significant differences (3.3 +/- 0.4 vs. 1.3 +/- 0.2).
Voigtländer
T
T
II. Medizinische Klinik und Poliklinik Johannes-Gutenberg-Universität Mainz Langenbeckstr. 1, 55131 Mainz, Germany. voigt@2-med.klinik.uni-mainz.de
Kreitner
K F
KF
Wittlinger
T
T
Petersen
S
S
Horstick
G
G
Kalden
P
P
Meyer
J
J
D001783:Blood Flow Velocity / Q000502:physiology; D001026:Coronary Artery Bypass; D003326:Coronary Circulation / Q000502:physiology*; D003327:Coronary Disease / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D006083:Graft Occlusion, Vascular / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography; D012680:Sensitivity and Specificity