title: [Reconstruction of the diaphragm with a polytetrafluoroethylene patch in neonates with congenital diaphragmatic hernia].
abstract: The authors present their experience with the reconstruction of the diaphragm with a synthetic polytetrafluoroethylene patch in a group of 66 neonates with a congenital diaphragmatic hernia. After preoperative stabilization 53 neonates (80%) were operated, simple reconstruction of the diaphragm was made in 39 neonates (74%), reconstruction of the diaphragm with a polytetrafluoroethylene patch was indicated in 14 patients (26%). Nine patients recovered after reconstruction of the diaphragm by a synthetic patch without complications. The only relapse of diaphragmatic hernia when using a patch was recorded in a neonate with a bilateral diaphragmatic hernia, sternal cleft and omphalocele. After simple reconstruction of the diaphragm there was no relapse of hernia. The total mortality in the group was 27% (18 neonates). After surgery five neonates died. Two of them died of serious haemorrhagic complications during extracorporeal membrane oxygenation and three died after operations performed at borderline oxygenation and ventilation values and subsequent deterioration of the general condition. In four of them a polytetrafluoroethylene patch (GORE-TEX) was used. Reconstruction of the diaphragm by a polytetrafluoroethylene patch is a suitable surgical method in the treatment of neonates with a congenital diaphragmatic hernia. Indication for the use of a patch is agenesis of the diaphragm and major diaphragmatic defects with hypoplastic borders. The use of a non-absorbable synthetic patch is from the aspect of the long-term effect on growth and the development of skeletal deformities equivocal and will call for further detailed studies.
authors.affiliation: Klinika dĕtské chirurgie 2. LF UK a FN Motol, Subkatedra dĕtské chirurgie IPVZ, Praha. mrygl@yahoo.com
authors.forename: M
authors.initials: M
authors.lastname: Rygl
authors.forename: K
authors.initials: K
authors.lastname: Pýcha
authors.forename: J
authors.initials: J
authors.lastname: Snajdauf
authors.forename: R
authors.initials: R
authors.lastname: Skába
authors.forename: J
authors.initials: J
authors.lastname: Melichar
authors.forename: J
authors.initials: J
authors.lastname: Janota
authors.forename: Z
authors.initials: Z
authors.lastname: Stranák
mesh_terms: D003964:Diaphragm / Q000601:surgery*; D006548:Hernia, Diaphragmatic / Q000601:surgery*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D011300:Preoperative Care; D013526:Surgical Mesh
chemical_list: D011138:Polytetrafluoroethylene