Spermatotoxic effect of carbendazim.
Carbendazim, suspended in sunflower oil, was administered to Wistar male rats through an oral intubation at a daily dose of 25 mg/kg body weight for 48 days, and the cauda epididymal sperm were analysed on day 49 for counts, motility and abnormalities. The study indicates that carbendazim affects the cauda epididymal sperm as seen in decreased sperm counts, inhibition of motility and increased incidence of abnormalities.
Akbarsha
M A
MA
Department of Animal Science, School of Life Sciences, Bharathidasan University, Tiruchirappalli, India.
Kadalmani
B
B
Girija
R
R
Faridha
A
A
Hamid
K S
KS
D000818:Animals; D001562:Benzimidazoles / Q000633:toxicity*; D002219:Carbamates; D004822:Epididymis / Q000187:drug effects; D005659:Fungicides, Industrial / Q000633:toxicity*; D008297:Male; D051381:Rats; D013076:Sperm Count; D013081:Sperm Motility / Q000187:drug effects; D013083:Sperm Transport / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects*
D001562:Benzimidazoles; D002219:Carbamates; D005659:Fungicides, Industrial; C006698:carbendazim