[The percentage of free prostate specific antigen used in detecting prostate cancer].
OBJECTIVE
To evaluate the value of the percentage of free prostate specific antigen in detecting prostate cancer.


METHODS
Serum free prostate specific antigen (F-PSA) and total PSA were measured with immunoradiometric assay, and the free/total PSA ratio was calculated. In 117 patients, 31 had prostate carcinoma and 86 BPH.


RESULTS
The free/total PSA ratio was lower in patients with prostate cancer than in those with BPH. If the total serum PSA level was limited with in 4 - 10 ng/ml, the free/total PSA ratio can be used in the differential diagnosis of prostate cancer and BPH except total PSA.


CONCLUSIONS
The free/total PSA ratio can be used in the differential diagnosis of prostate cancer and BPH, especially when serum PSA level is limited with in 4 - 10 ng/ml.
Yang
L
L
Department of Urology, Huashan Hospital, Shanghai Medical University, Shanghai 200040.
Fang
Z
Z
Song
J
J
Deng
S
S
D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D006801:Humans; D015592:Immunoradiometric Assay; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D017430:Prostate-Specific Antigen / Q000097:blood*; D011470:Prostatic Hyperplasia / Q000175:diagnosis*; D011471:Prostatic Neoplasms / Q000175:diagnosis*
D017430:Prostate-Specific Antigen