Structure, conformation, and mechanism in the membrane transport of alkali metal ions by ionophoric antibiotics.
Recent progress in studies of the mechanism of transport of alkali metal ions by ionophoric antibiotics and the structures of alkali metal salts of the ionophores monensin and narasin is reviewed. The structures obtained from 2D NMR experiments in solution provide considerable insights into the mechanisms of transport.
Riddell
Frank G
FG
School of Chemistry, The University of St Andrews, St Andrews, Scotland, UK. fgr@st-and.ac.uk
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D007476:Ionophores; D009682:Magnetic Resonance Spectroscopy; D008670:Metals / Q000737:chemistry*; D008958:Models, Molecular
D000900:Anti-Bacterial Agents; D007476:Ionophores; D008670:Metals