title: [The clinical effects of percutaneous lumbar discectomy combined with sodium hyaluronate in the treatment of lumbar intervertebral disc herniation].
abstract: OBJECTIVE
  To investigate the therapeutic effect of percutaneous lumbar discectomy (PLD) combined with sodium hyaluronate (SH) injection in the treatment of lumbar intervertebral disc herniation.
  
  
  METHODS
  Forty-eight patients suffered from lumbar disc herniation were divided into two groups and treated by PLD combined with SH injection into epidural cavity (treatment group) or single PLD (control group) respectively. All patients were followed up for 24 months. The therapeutic effects in both groups were assessed and compared according to Macnab's criterion.
  
  
  RESULTS
  The patients in the treatment group got much more significant improvement than those in the control group, with shorter therapeutic course and more safety.
  
  
  CONCLUSIONS
  PLD combined with SH injection into epidural cavity is more effective and safety in the treatment of lumbar disc herniation than of pure PLD.
authors.affiliation: Department of Radiology, Second Out-patient Department, First Affiliated Hospital of Harbin Medical University, Harbin Heilongjiang, P. R. China 150001.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Yu-lin
authors.initials: YL
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: Yang
authors.forename: Feng-lin
authors.initials: FL
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017587:Diskectomy, Percutaneous / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D007405:Intervertebral Disc Displacement / Q000188:drug therapy* / Q000601:surgery; D008159:Lumbar Vertebrae / Q000187:drug effects* / Q000601:surgery; D008297:Male; D008875:Middle Aged
chemical_list: D006820:Hyaluronic Acid