title: Habitual fat intake and basal fat oxidation in obese and non-obese Caucasians.
abstract: OBJECTIVE
  To examine the relationship between habitual fat intake and basal fat oxidation in obese and non-obese Caucasian men and women.
  
  
  METHODS
  Habitual fat intake was assessed by 7-day weighed dietary records and resting fat oxidation was determined after an overnight fast in 132 weight stable non-diabetic subjects (38 males, 94 females). All subjects were characterized for weight, height, waist-to-hip ratio, physical activity, plasma glucose and insulin response to an oral glucose load, plasma catecholamine and leptin levels. Under-reporters, defined according to plausibility of the relationship between energy expenditure and energy intake, were excluded from the analyses.
  
  
  RESULTS
  The mean age was 53.1+/-10.6 y (19-72 y) and mean body mass index (BMI) was 30.7+/-5.8 kg/m(2) (19.4-45.8 kg/m(2)). Sixty-eight subjects were obese (BMI>30 kg/m(2)). Univariate regression analysis revealed a significant, albeit modest, relationship between absolute fat intake and BMI (r(2)=0.06; P<or=0.05) but not between fat intake and fat mass (r(2)=0.026; P=0.08). However, multiple regression analysis revealed significant effects of body fat mass (FM) and sex on basal fat oxidation (bFO) explaining 33% of the variation of bFO (P<or=0.0001; radical s.e.=18.0 g/24 h). In univariate regression analysis, habitual fat intake was significantly related to adjusted fat oxidation, explaining 12% of the variation (P<or=0.0001; radical s.e.=11.7 g/24 h).
  
  
  CONCLUSIONS
  Habitual fat intake has a significant, albeit modest, effect on basal fat oxidation, even when adjusted for sex and body FM. The rather modest effect of habitual fat intake on fat oxidation may in part explain the increased propensity to gain FM on a high-fat diet.
authors.affiliation: German Institute of Human Nutrition, Division of Biochemistry and Physiology of Nutrition, Potsdam-Rehbrücke, Germany.
authors.forename: I
authors.initials: I
authors.lastname: Kunz
authors.forename: U
authors.initials: U
authors.lastname: Schorr
authors.forename: K
authors.initials: K
authors.lastname: Römmling
authors.forename: S
authors.initials: S
authors.lastname: Klaus
authors.forename: A M
authors.initials: AM
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000368:Aged; D001481:Basal Metabolism; D001786:Blood Glucose / Q000378:metabolism; D002395:Catecholamines / Q000097:blood; D015930:Diet Records; D004041:Dietary Fats / Q000008:administration & dosage*; D002149:Energy Intake; D004734:Energy Metabolism; D015444:Exercise; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D010084:Oxidation-Reduction
chemical_list: D001786:Blood Glucose; D002395:Catecholamines; D004041:Dietary Fats; D007328:Insulin; D020738:Leptin