Synthesis and antimicrobial activity of some imidazo-[1,2-a]pyridine-2- carboxylic acid arylidenehydrazide derivatives.
Imidazo[1,2-a]pyridine-2-carboxylic acid, ethyl esters were reacted with hydrazine hydrate to furnish imidazo[1,2-a]pyridine-2-carboxylic acid hydrazide. The hydrazides formed were treated with various aldehydes to obtain 28 imidazo[1,2-a]pyridine-2-carboxylic acid arylidenehydrazides. Antimicrobial activity of the compounds were examined.
Turan-Zitouni
G
G
Anadolu University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Eskisehir, Turkey.
Blache
Y
Y
Güven
K
K
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D007093:Imidazoles