title: Perianal ulcerations from topical steroid use.
abstract: Topical steroids play an extremely important role in the treatment of various dermatologic conditions. Use of topical steroids must be approached with caution, however, as they can have serious side effects. We report a case of iatrogenic perianal ulcers caused by twice-daily application of Lotrisone (clotrimazole and betamethasone dipropionate) in the perianal region. High-potency topical steroids should be used sparingly and briefly in intertriginous areas.
authors.affiliation: Department of Dermatology, University of Cincinnati, College of Medicine, Ohio 45267-0523, USA. brianadams@pol.net
authors.forename: Brian B
authors.initials: BB
authors.lastname: Adams
authors.forename: Pranav B
authors.initials: PB
authors.lastname: Sheth
mesh_terms: D000279:Administration, Cutaneous; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001004:Anus Diseases / Q000188:drug therapy; D001623:Betamethasone / Q000008:administration & dosage / Q000009:adverse effects*; D002081:Buttocks; D002177:Candidiasis / Q000188:drug therapy; D003022:Clotrimazole / Q000008:administration & dosage / Q000009:adverse effects*; D003920:Diabetes Mellitus; D003937:Diagnosis, Differential; D004338:Drug Combinations; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid; D012651:Self Medication; D012883:Skin Ulcer / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology
chemical_list: D000935:Antifungal Agents; D004338:Drug Combinations; C452620:Lotrisone; D001623:Betamethasone; D003022:Clotrimazole