[Frequency of stable chromosomal aberrations determined by FISH in 49 Chernobyl nuclear accident liquidators exposed to various doses of radiation].
FISH technique was tested on the 49 liquidators of the Chernobyl Accident. Groups were formed according to average group exposure doses and/or individual ones determined by the method of EPR. The essential variability of spontaneous and irradiation-induced frequencies of reciprocal translocations was observed. In groups with the lowest EPR-doses (below 25 cGy) the average cytogenetic dose was considerably higher then doses determined by EPR-method. The best coincidences between average in-group EPR- and FISH-doses were in the group with 25-50 cGy doses for "acute irradiation" model and in the group with 50-100 cGy and higher for "chronic irradiation" model.
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D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations / Q000528:radiation effects*; D003743:Dental Enamel / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000379:methods; D008297:Male; D008875:Middle Aged; D011210:Power Plants; D011834:Radiation Monitoring; D018788:Radioactive Hazard Release; D012189:Retrospective Studies; D014455:Ukraine