Toward the creation of NMR databases in chiral solvents: bidentate chiral NMR solvents for assignment of the absolute configuration of acyclic secondary alcohols.
The absolute configuration of acyclic secondary alcohols can be established from analysis of the chemical shift behaviors of the adjacent carbons in bidentate chiral solvents (R,R)- and (S,S)-1d as formulated in the boxed illustration.
Kobayashi
Yoshihisa
Y
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
Hayashi
Nobuyuki
N
Kishi
Yoshito
Y
D000438:Alcohols / Q000737:chemistry*; D016208:Databases, Factual; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D012997:Solvents / Q000737:chemistry*; D013237:Stereoisomerism
D000438:Alcohols; D012997:Solvents