Inflammation in acute coronary syndromes.
Extensive evidence supports a pathogenic role for both local and systemic inflammation in acute coronary syndromes. However, several important questions remain unanswered. Is the observed inflammatory process a precursor or a consequence of coronary plaque rupture? Is the inflammatory component of unstable coronary disease a potential therapeutic target? Finally, do infectious agents have a pathogenic role in coronary atherosclerosis and acute coronary syndromes?
Mulvihill
N T
NT
Department of Cardiology, St James's Hospital, Dublin 8, Republic of Ireland. mulvihin@hotmail.com
Foley
J B
JB
D000789:Angina, Unstable / Q000473:pathology; D015415:Biomarkers; D002097:C-Reactive Protein / Q000378:metabolism; D015815:Cell Adhesion Molecules / Q000378:metabolism; D003324:Coronary Artery Disease / Q000150:complications / Q000473:pathology; D003328:Coronary Thrombosis / Q000473:pathology; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000150:complications; D009203:Myocardial Infarction / Q000473:pathology; D017202:Myocardial Ischemia / Q000209:etiology / Q000473:pathology*; D014777:Virus Diseases / Q000150:complications
D015415:Biomarkers; D015815:Cell Adhesion Molecules; D016207:Cytokines; D002097:C-Reactive Protein