[Motor-evoked potential in investigating neurologic function during spinal cord ischemia and reperfusion injury].
OBJECTIVE
To investigate the method monitoring the neurologic function of spinal cord ischemia and reperfusion injury.


METHODS
Motor-evoked potentials (MEP)were monitored at different time points during ischemia and reperfusion of the lumbar spinal cord of the rat.


RESULTS
MEP latency increased 15 minutes after ischemia (P < 0.01) and MEP amplitude decreased 25 minutes after ischemia (P < 0.01). MEP disappeared 40 minutes after ischemia and reappeared 5 minutes after reperfusion, but the latency was still longer and the amplitude was lower than the normal value (P < 0.01). The amplitude returned to normal 2 hours after reperfusion (P > 0.05) in contrast to the latency. 24 hours after reperfusion, the amplitude decreased again, and motor function of rat hind limbs was more decreased than that at early time of reperfusion (P < 0.05).


CONCLUSIONS
MEP is a sensitive index for spinal cord ischemia and reperfusion injury.
Yu
Z
Z
Department of Orthopaedics, Third Teaching Hospital of Beijing Medical University, Beijing 100083.
Liu
Z
Z
Dang
G
G
D000818:Animals; D019054:Evoked Potentials, Motor / Q000502:physiology*; D006614:Hindlimb / Q000294:innervation / Q000503:physiopathology; D007511:Ischemia / Q000503:physiopathology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D015427:Reperfusion Injury / Q000503:physiopathology*; D013116:Spinal Cord / Q000098:blood supply*