[Hashimoto's thyroiditis in "struma ovarii". Case report and review of the literature].
Struma ovarii, a teratoma in which thyroid tissue is the predominant or sole component account for 2.7% of all ovarian tumors. Pathogenesis is unclear. In addition to symptoms and signs caused by the presence of a mass, struma may be associated with a number of unusual clinical manifestations. Ascitis occurs in approximately one third of the cases, Meigs' syndrome occasionally and hyperthyroidism in only about 5% of cases. Thyroiditis is an occasional finding and Hashimotos' thyroiditis is rare in struma ovarii. The struma may resemble normal thyroid tissue, a thyroid adenoma or thyroid carcinoma. The treatment is surgical and the outcome generally favorable. This paper reports the first clinical case of a patient with Hashimoto's thyroiditis in a pure struma ovarii associated with positive specific antithyroid antibodies in the absence of symptoms and signs due to thyroid disease.
Bonadio
A G
AG
Dipartimento di Oncologia, Divisione di Anatomia Patologica I, Università degli Studi, Pisa, Italy.
D001323:Autoantibodies / Q000276:immunology; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013330:Struma Ovarii / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013967:Thyroiditis, Autoimmune / Q000209:etiology* / Q000276:immunology / Q000473:pathology / Q000601:surgery
D001323:Autoantibodies; C056626:thyroid microsomal antibodies