title: [Absence of a decrease in nocturnal arterial pressure as an independent prognostic factor in hypertension].
abstract: Considerable evidence has accumulated indicating that the lack of the normal nocturnal fall in blood pressure (non-dipper) may represent an important prognostic factor in hypertension. This review focuses on clinical studies showing close association between a non-dipper pattern of blood pressure and cardiovascular events such as glomerular capillary hypertension, cerebrovascular events, left ventricular hypertrophy and ventricular arrhythmias. A close relationship between impairment of the circadian rhythm of blood pressure and that of natriuresis is described. The therapeutic profit from the knowledge that a given patient is a non-dipper and/or salt-sensitive is illustrated.
authors.affiliation: Ustav patologické fyziologie LF UP, Olomouc.
authors.forename: J
authors.initials: J
authors.lastname: Veselý
mesh_terms: D001794:Blood Pressure / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000209:etiology; D002940:Circadian Rhythm; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D011379:Prognosis; D012307:Risk Factors; D017673:Sodium Chloride, Dietary / Q000494:pharmacology
chemical_list: D017673:Sodium Chloride, Dietary