title: [Hemodynamic and pathologic changes in open abdominal wound after seawater immersion in dog].
abstract: OBJECTIVE
  To study the experimental basis for the treatment to the sick and wounded with abdominal open wound in land warfare and naval battle.
  
  
  METHODS
  Animal model was made with adult dogs to observe the changes of mean artery pressure (MAP), pulmonary capillary wedge pressure (PCWP), central vein pressure (CVP), cardiac output (CO), cardiac index (CI) and pathologic changes of heart, pulmonary, hepatic, nephritic, intestinal, and gastric tissues under the optical and electrical microscope.
  
  
  RESULTS
  Comparing with simple open abdominal, the hemodynamic disorder in open wound after seawater immersion was more serious; with a higher death rate.
  
  
  CONCLUSIONS
  There was differences in hemodynamic and pathologic changes in seawater immersion wound and general wound. The body damaged is seriously when open abdominal wound immersed in seawater. Special measure must be taken in treating open abdominal wound after seawater immersion.
authors.affiliation: Department of General Surgery, Naval General Hospital, Beijing 100037, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: E
authors.initials: E
authors.lastname: Lu
authors.forename: J
authors.initials: J
authors.lastname: Yu
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: D
authors.initials: D
authors.lastname: Wang
authors.forename: Z
authors.initials: Z
authors.lastname: Zhou
mesh_terms: D000007:Abdominal Injuries / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology*; D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D006439:Hemodynamics; D007101:Immersion / Q000503:physiopathology*; D008297:Male; D011897:Random Allocation; D012623:Seawater; D014950:Wounds, Penetrating / Q000150:complications / Q000662:veterinary*