title: [Histamine-1 and -2 receptors in hepatic tissues of cirrhotic patients with portal hypertension].
abstract: OBJECTIVE
  To study histamine-1 and histamine-2 receptors in hepatic tissues of cirrhotic patients with portal hypertension.
  
  
  METHODS
  Light autoradiography was used.
  
  
  RESULTS
  The density of histamine-2 (H-2) receptors (cirrhotic patients/controls) in hepatocytes was 168.4 +/- 22.6/511.9 +/- 37.6 (P < 0.01), in hepatic vein 238.8 +/- 40.7/313.0 +/- 52.4 (P < 0.01), in hepatic artery 55.6 +/- 7.1/175.4 +/- 26.1 (P < 0.01), and in portal vein 52.0 +/- 5.4/166.4 +/- 17.7 (P < 0.01). The density of histamine-1 receptors in hepatocytes, hepatic vein, hepatic artery and portal vein was not statistically changed between cirrhotic patients and controls (P > 0.05).
  
  
  CONCLUSIONS
  The density of H-2 receptors in hepatic tissues of cirrhotic patients decreased significantly.
authors.affiliation: Department of General Surgery, 252nd Hospital of People's Liberation Army, Baoding 071000.
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
authors.forename: X
authors.initials: X
authors.lastname: Leng
authors.forename: H
authors.initials: H
authors.lastname: Feng
authors.forename: F
authors.initials: F
authors.lastname: Ma
authors.forename: B
authors.initials: B
authors.lastname: Wang
mesh_terms: D000328:Adult; D001345:Autoradiography; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications*; D008099:Liver / Q000378:metabolism*; D008103:Liver Cirrhosis / Q000150:complications / Q000378:metabolism*; D008875:Middle Aged; D011969:Receptors, Histamine H1 / Q000378:metabolism*; D011970:Receptors, Histamine H2 / Q000378:metabolism*
chemical_list: D011969:Receptors, Histamine H1; D011970:Receptors, Histamine H2