title: Rheumatoid arthritis. The genetic components.
abstract: Rheumatoid arthritis is a multifactorial disease, with genetic, environmental, and stochastic components to its susceptibility. The search for susceptibility genes is still in progress. Preliminary results suggest the involvement of multiple genes, each with relatively modest effect. Genes within the major histocompatibility complex appear to have the strongest influence on disease susceptibility.
authors.affiliation: Division of Biology and Human Genetics, North Shore University Hospital, Manhasset, New York, USA.
authors.forename: Damini
authors.initials: D
authors.lastname: Jawaheer
authors.forename: Peter K
authors.initials: PK
authors.lastname: Gregersen
mesh_terms: D001172:Arthritis, Rheumatoid / Q000453:epidemiology / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D015995:Prevalence
chemical_list: D006680:HLA Antigens