Limnantheoside C (20-hydroxyecdysone 3-O-beta-D-glucopyranosyl-[1-->3]-beta-D-xylopyranoside), a phytoecdysteroid from seeds of Limnanthes alba (limnanthaceae).
A new ecdysteroid glycoside, limnantheoside C (20-hydroxyecdysone 3-O-beta-D-glucopyranosyl-[-->3]-beta-D-xylopyranoside [1]), together with limnantheoside A (20-hydroxyecdysone 3-O-beta-D-xylopyranoside [2]) and 20-hydroxyecdysone (3) have been isolated by bioassay/RIA-directed HPLC analyses of a methanol extract of the seedmeal of Limnanthes alba Hartw. ex Benth. The structure of the novel ecdysteroid glycoside (1) was determined unambiguously by UV, LSIMS and a combination of 1D- and 2D-NMR experiments. These three compounds are isolated from Limnanthes alba for the first time.
Meng
Y
Y
Department of Biological Sciences, University of Exeter, Hatherly Laboratories, Devon, UK.
Whiting
P
P
Sik
V
V
Rees
H H
HH
Dinan
L
L
D000818:Animals; D019607:Brassicaceae / Q000737:chemistry*; D002460:Cell Line; D004331:Drosophila melanogaster / Q000187:drug effects; D004440:Ecdysone / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification; D026461:Ecdysteroids / Q000737:chemistry* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology; D008958:Models, Molecular; D015394:Molecular Structure; D011863:Radioimmunoassay; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D012639:Seeds / Q000737:chemistry*
D026461:Ecdysteroids; D006027:Glycosides; D012503:Saponins; C448639:limnantheoside C; D004440:Ecdysone