Molecular identity and regulation of renal potassium channels.
K channels are ubiquitous in animal cells, where they are involved in a variety of physiological functions. In epithelial cells of the kidney, K channels are primarily involved in maintaining membrane potential, recycling and secreting K and regulating cell volume. As many renal K channels have now been studied or identified at the molecular level by means of a variety of approaches, including patch-clamp recordings, cDNA cloning and immunohistochemistry, the purpose of this review is to summarize what is presently known about the molecular identity of renal K channels with an emphasis on their regulatory properties.
Noulin
J F
JF
Groupe de recherche en transport membranaire, Department of Physiology, Université de Montréal, Montréal, QC, H3C3J7, Canada. jean-yves.lapointe@umontreal.ca
Brochiero
E
E
Coady
M J
MJ
Laprade
R
R
Lapointe
J Y
JY
D000818:Animals; D006801:Humans; D007684:Kidney Tubules / Q000502:physiology*; D015221:Potassium Channels / Q000737:chemistry* / Q000145:classification / Q000502:physiology*
D015221:Potassium Channels