[Diagnostic value of serum creatine kinase MB in patients with cardiac damage after electric injuries].
OBJECTIVE
To investigate the incidence of cardiac damage and the diagnostic value of serum myocardial enzyme following electric injuries.


METHODS
32 patients with electrical contact injuries were evaluated by serial electrocardiograms (ECG), creatine kinase (CK) and creatine kinase MB isoenzyme (CK-MB) determinations. The patients were divided into two groups according to the ECG.


RESULTS
17 patients showed abnormal ECG (Group A), and 15 normal ECG (Group B). Positive correlations were noted between CK, CK-MB and the size of electric burns. The difference of serum CK-MB and 1.1% of total CK (CK-MB in skeletal muscle) was defined as CK-MB difference. CK, CK-MB, CK-MB/total CK ratio and the CK-MB difference were significantly higher in group A than in group B (all P < 0.05). The CK-MB difference of 88% (15/17) patients in group A was more than 25 U/L, whereas that was 6.7% (1/15) in group B (P < 0.01). Six patients with CK-MB difference greater than 100 U/L had obvious cardiac damage.


CONCLUSIONS
Cardiac damage is a common complication of electric injuries. The cardiac damage could be estimated by serum CK-MB, particularly by the CK-MB difference. The CK-MB difference might be a useful indicator for evaluating the severity of the cardiac damage.
Zhang
B
B
Burn Department, Central Hospital Affiliated to Shenyang Medical College, Shenyang 110024.
Yang
Y
Y
Tian
Y
Y
Li
G
G
Zhang
X
X
Li
M
M
Hao
Z
Z
D000293:Adolescent; D000328:Adult; D000368:Aged; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D003402:Creatine Kinase / Q000097:blood*; D052279:Creatine Kinase, MB Form; D004556:Electric Injuries / Q000150:complications*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D012720:Severity of Illness Index
D007527:Isoenzymes; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form