title: Geno3D: automatic comparative molecular modelling of protein.
abstract: Geno3D (http://geno3d-pbil.ibcp.fr) is an automatic web server for protein molecular modelling. Starting with a query protein sequence, the server performs the homology modelling in six successive steps: (i) identify homologous proteins with known 3D structures by using PSI-BLAST; (ii) provide the user all potential templates through a very convenient user interface for target selection; (iii) perform the alignment of both query and subject sequences; (iv) extract geometrical restraints (dihedral angles and distances) for corresponding atoms between the query and the template; (v) perform the 3D construction of the protein by using a distance geometry approach and (vi) finally send the results by e-mail to the user.
authors.affiliation: Institut de Biologie et Chimie des Protéines, IBCP-CNRS UMR 5086, Pôle Bioinformatique Lyonnais, Bioinformatics and structural NMR, 7, Passage du Vercors, 69 367 Lyon Cedex 07, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Combet
authors.forename: Martin
authors.initials: M
authors.lastname: Jambon
authors.forename: Gilbert
authors.initials: G
authors.lastname: Deléage
authors.forename: Christophe
authors.initials: C
authors.lastname: Geourjon
mesh_terms: D000465:Algorithms; D019295:Computational Biology; D003198:Computer Simulation; D020407:Internet; D008958:Models, Molecular; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment / Q000706:statistics & numerical data; D017386:Sequence Homology, Amino Acid
chemical_list: D011506:Proteins