title: [Midazolam sedation in the general dental practice].
abstract: The general dental practitioner is occasionally confronted with patients who, on the basis of psychological--and often somatic--criteria, are difficult to treat. Medicinal sedation in combination with anxiety reduction may be deemed appropriate for such patients. In the Netherlands inhalation sedation by means of a combination of oxygen and nitrous oxide is generally used. The limitations and disadvantages of this method have directed attention towards sedation by means of midazolam, a quick-acting benzodiazepine. In view of the complications which may accompany the administration of midazolam, the general practitioner working alone or in a group practice is advised against using midazolam sedation. Such use should be reserved for a dentist working in a hospital setting, who is able to consult with a physician regarding the advisability of administering midazolam. Even then, the safety of the patient requires that the practitioners have a proper insight into the physical state of the patient, work according to a protocol and in accordance with clearly defined responsibilities, and provide adequate accommodation during and after treatment.
authors.affiliation: Vakgroep Algemene Ziekteieer en Inwendige Geneeskunde, Academisch Centrum Tandheelkunde Amsterdam (ACTA), Louwesweg 1, 1066 EA Amsterdam.
authors.forename: J
authors.initials: J
authors.lastname: Bertens
authors.forename: L
authors.initials: L
authors.lastname: Abraham-Inpijn
authors.forename: P J
authors.initials: PJ
authors.lastname: Meuwissen
mesh_terms: D000766:Anesthesia, Dental / Q000379:methods; D016854:Dental Anxiety / Q000188:drug therapy*; D003729:Dental Care / Q000379:methods; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D008874:Midazolam / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D012449:Safety
chemical_list: D006993:Hypnotics and Sedatives; D008874:Midazolam