DNA microarrays for malaria.
DNA microarrays are a powerful tool for the analysis of RNA and DNA composition on a whole-genome scale. The first applications of this technology in parasitology are in place. This review examines the various approaches to Plasmodium transcript-profiling that are being adopted using DNA microarray analysis and discusses additional strategies for obtaining and collating information relevant to the search for drug and vaccine candidates in malaria.
Rathod
Pradipsinh K
PK
Dept. of Chemistry, University of Washington, Seattle, WA 98195, USA. rathod@chem.washington.edu
Ganesan
Karthikeyan
K
Hayward
Rhian E
RE
Bozdech
Zbynek
Z
DeRisi
Joseph L
JL
D000818:Animals; D004351:Drug Resistance / Q000235:genetics; D020869:Gene Expression Profiling; D006801:Humans; D008018:Life Cycle Stages; D016778:Malaria, Falciparum / Q000235:genetics* / Q000517:prevention & control; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D010961:Plasmodium / Q000235:genetics*; D014611:Vaccination