Possible triggering effect of cytomegalovirus infection on systemic lupus erythematosus.
We report on a patient with systemic lupus erythematosus (SLE) who showed elevated titers of IgM antibodies to cytomegalovirus (CMV), suggesting CMV infection at the onset of SLE. Serum CMV antigens were also detected in the patient. These findings raise the possibility that CMV infection may be related to the onset of SLE in certain patients.
Nawata
M
M
Department of Medicine, Juntendo University Izu-Nagaoka Hospital, Shizuoka, Japan.
Seta
N
N
Yamada
M
M
Sekigawa
I
I
Lida
N
N
Hashimoto
H
H
D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis*; D001774:Blood Chemical Analysis; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D016133:Polymerase Chain Reaction; D011239:Prednisolone / Q000008:administration & dosage; D018570:Risk Assessment
D000914:Antibodies, Viral; D004279:DNA, Viral; D011239:Prednisolone