title: [Study on perinatal group B Streptococcus carriers and the maternal and neonatal outcome].
abstract: OBJECTIVE
  To investigate the group B streptococcus (GBS) colonization rate and the relationship between vaginal colonization of GBS and the maternal and neonatal outcome.
  
  
  METHODS
  3% TH selective broth media were used for culture of GBS. The vaginal samples were collected during different pregnant periods (before 20 weeks' gestation; 20-28 weeks; after 34 weeks' gestation) and other samples from different sites after labor (including neonatal throat, ear, umbilicus and placenta, umbilical blood, maternal blood, etc).
  
  
  RESULTS
  The GBS carrier rate in 1 039 pregnant women was 11.07% (115/1,039). The colonization rate of different treating times was 29.73% (test three times), 15.50% (test twice) and 9.86% (test one time) respectively. The carrier rate of three-time-test was significantly higher than that of two times test (P < 0.01) and that of only one time (P < 0.01). The carrier rate in three periods was 16.84% (< 20 weeks), 18.40% (20-28 weeks) and 14.90% (> 34 weeks) respectively. Obstetric complications associated with GBS carrier were similar with those of non-carrier. Neonatal carrier rate was 9.95%. The neonatal carrier rate in the group of carrier mothers was higher than that of non-carrier mothers (14.29%:7.26%). The rate of neonatal pneumonia and the upper respiratory tract infection in GBS-carrier-mother was higher than that of non-carrier mothers (11.01%:9.71%; 8.27%: 6.07%) while it was similar in neonatal carrier group and non-carrier group (20.00%:14.92%; 10.00%:4.97%).
  
  
  CONCLUSIONS
  GBS might be one of vaginal pathogens in Chinese women, but it is not severe enough to threaten the health of pregnant women and their newborns.
authors.affiliation: Department of Obsterics, Beijing Obstetric and Gynecology Hospital, Medical Science of Capital University, Beijing 100006, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Ma
authors.forename: L
authors.initials: L
authors.lastname: Wu
authors.forename: X
authors.initials: X
authors.lastname: Huang
mesh_terms: D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000382:microbiology*; D007743:Labor, Obstetric; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology* / Q000517:prevention & control; D011256:Pregnancy Outcome; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D014472:Umbilicus / Q000382:microbiology; D014621:Vagina / Q000382:microbiology*