title: Comparison of urinary albumin excretion rate in overnight urine and albumin creatinine ratio in spot urine in diabetic patients in general practice.
abstract: OBJECTIVE
  To evaluate whether measurement of albumin creatinine ratio (ACR) on a spot urine specimen can replace a timed overnight collection of urine albumin excretion rate (UAER) in patients with diabetes in primary care.
  
  
  METHODS
  Patients with diabetes attending Rønvik Health Centre were asked to bring a timed overnight collection of urine for measurement of UAER. They were also asked to void a urine specimen for measurement of albumin creatinine ratio.
  
  
  METHODS
  Primary health care.
  
  
  METHODS
  One-hundred-and-six persons with diabetes (47 women, 59 men) aged 13 to 78 years.
  
  
  RESULTS
  The sensitivity and specificity of ACR with cut-off values of 2.5 mg/mmol for men and 3.5 mg/mmol for women compared to UAER with cut-off value of 20 mg/24 h was 90%.
  
  
  CONCLUSIONS
  Spot urine ACR analysed on a DCA 2000 can replace a timed (overnight) collection of urine and measurement of UAER when diabetic patients are reviewed in general practice. This simplifies procedures for the patient as a timed urine collection is no longer necessary. Another advantage is that the results are available after 7 min.
authors.affiliation: Rønvik Health Centre, Bodø, Norway. tclaudi@online.no
authors.forename: T
authors.initials: T
authors.lastname: Claudi
authors.forename: J G
authors.initials: JG
authors.lastname: Cooper
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000419:Albuminuria; D003404:Creatinine / Q000652:urine*; D003920:Diabetes Mellitus / Q000652:urine*; D003955:Diagnostic Tests, Routine / Q000379:methods*; D005194:Family Practice / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009664:Norway; D012680:Sensitivity and Specificity
chemical_list: D003404:Creatinine