title: Vaticanol C, a novel resveratrol tetramer, inhibits cell growth through induction of apoptosis in colon cancer cell lines.
abstract: A novel resveratrol tetramer, vaticanol C, isolated from the stem bark of Vatica rassak markedly suppressed cell growth through induction of apoptosis, which was characterized by nuclear changes and DNA ladder formation, in three different human colon cancer cell lines.
authors.affiliation: Gifu Pharmaceutical University, Mitahora-higashi, Japan.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Ito
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Akao
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Tanaka
authors.forename: Munekazu
authors.initials: M
authors.lastname: Iinuma
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nozawa
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D003110:Colonic Neoplasms / Q000188:drug therapy*; D004273:DNA, Neoplasm / Q000187:drug effects; D006801:Humans; D008970:Molecular Weight; D019441:Plant Epidermis / Q000737:chemistry; D000077185:Resveratrol; D013267:Stilbenes / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004273:DNA, Neoplasm; D013267:Stilbenes; C459559:vaticanol C; D000077185:Resveratrol