Conduction system in cardiac amyloidosis: two cases succumbed to cardiac arrest.
The present article reports the histological study of the conduction system in 2 cases of cardiac amyloidosis. The discrepant anatomical and clinical evidence yet confirmed the need for accurate ECG controls in all cases. Indeed, while in the first case evident lesions of the conduction system were revealed by surface ECGs, the second case did not exhibit significant ECG abnormalities but the right atrium and the His bundle showed slight fibro-amyloid involvement, as potential forerunners of high-risk arrhythmias.
Stefani
M
M
Institute of Anatomic Pathology, University of Milan, Milan, Italy. michele.stefani@unimi.it
Angiero
F
F
Rossi
L
L
D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology*; D003951:Diagnostic Errors; D004562:Electrocardiography; D005260:Female; D006323:Heart Arrest / Q000209:etiology*; D006329:Heart Conduction System / Q000473:pathology*; D006331:Heart Diseases / Q000473:pathology*; D006801:Humans; D008875:Middle Aged