title: Preoperative hyperthermochemoradiotherapy for esophageal carcinoma.
abstract: BACKGROUND
  In order to acquire an improved prognosis, preoperative hyperthermia combined with chemotherapy and radiotherapy (HCR) has been performed in our department for patients with esophageal carcinoma.
  
  
  METHODS
  The experimental and clinical investigations that have been continuously performed in our department were introduced with regard to the therapeutic effect brought by HCR for carcinoma, chiefly for esophageal carcinoma.
  
  
  RESULTS
  A series of our investigations have demonstrated the excellent anticancer effect of HCR for esophageal carcinoma.
  
  
  CONCLUSIONS
  Preoperative HCR has contributed to improvements in the prognosis of patients with esophageal carcinoma and is expected to make marked progress in the future with further development of anticancer agents and improvements in the hyperthermia devices.
authors.affiliation: Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Higashi-Ward, Fukuoka, Japan.
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Nozoe
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Saeki
authors.forename: Shuhei
authors.initials: S
authors.lastname: Ito
authors.forename: Takefumi
authors.initials: T
authors.lastname: Ohga
authors.forename: Kaoru
authors.initials: K
authors.lastname: Kitamura
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000401:mortality / Q000601:surgery / Q000628:therapy; D006801:Humans; D006979:Hyperthermia, Induced; D011300:Preoperative Care; D011878:Radiotherapy; D016032:Randomized Controlled Trials as Topic; D015996:Survival Rate
chemical_list: D000970:Antineoplastic Agents