title: Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniques.
abstract: OBJECTIVE
  To evaluate risks of cranial ultrasound abnormalities among very-low-birth-weight (VLBW) infants conceived with fertility therapy (ovulation induction only or with assisted reproductive techniques [ART]) and of multiple gestation pregnancies.
  
  
  METHODS
  The incidences of cranial ultrasound abnormalities in 1473 VLBW infants conceived with and without fertility therapy and born of multiple versus singleton pregnancies were compared, using logistic regression models.
  
  
  RESULTS
  Infants conceived with ART were less likely to have intraventricular hemorrhage (IVH). Twins and triplets had risks of cranial ultrasound abnormalities similar to those of singletons. Twins and triplets conceived with ART were at lower risk of IVH.
  
  
  CONCLUSIONS
  VLBW infants conceived with ART do not appear to be at increased risk of cranial ultrasound abnormalities. Likewise, twins and triplets were not at increased risk of these abnormalities.
authors.affiliation: Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
authors.forename: Jane E
authors.initials: JE
authors.lastname: Stewart
authors.forename: Elizabeth N
authors.initials: EN
authors.lastname: Allred
authors.forename: Margaret
authors.initials: M
authors.lastname: Collins
authors.forename: Jodi
authors.initials: J
authors.lastname: Abbott
authors.forename: Alan
authors.initials: A
authors.lastname: Leviton
authors.forename: Nigel
authors.initials: N
authors.lastname: Paneth
authors.forename: M Lynne
authors.initials: ML
authors.lastname: Reuss
authors.forename: Mervyn
authors.initials: M
authors.lastname: Susser
authors.forename: Thomas
authors.initials: T
authors.lastname: Hegyi
authors.forename: Mark
authors.initials: M
authors.lastname: Hiatt
authors.forename: Ulana
authors.initials: U
authors.lastname: Sanocka
authors.forename: Farrokh
authors.initials: F
authors.lastname: Shahrivar
authors.forename: Linda J
authors.initials: LJ
authors.lastname: Van Marter
authors.forename: Petra
authors.initials: P
authors.lastname: Banogan
authors.forename: David
authors.initials: D
authors.lastname: Genest
authors.forename: Debra
authors.initials: D
authors.lastname: Heller
authors.forename: Susan
authors.initials: S
authors.lastname: Shen-Schwarz
authors.forename: Olaf
authors.initials: O
authors.lastname: Dammann
authors.forename: Karl C K
authors.initials: KC
authors.lastname: Kuban
authors.forename: Marcello
authors.initials: M
authors.lastname: Pagano
mesh_terms: D001925:Brain Damage, Chronic / Q000000981:diagnostic imaging; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging* / Q000453:epidemiology; D015986:Confounding Factors, Epidemiologic; D004453:Echoencephalography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging* / Q000453:epidemiology; D019102:Infant, Very Low Birth Weight; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging / Q000453:epidemiology; D016015:Logistic Models; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011256:Pregnancy Outcome; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects; D018570:Risk Assessment; D014310:Triplets; D014427:Twins