title: [Turbidimetric express method in the assessment of the hemostasis parameters in patients with prosthetic bileaflet heart valves].
abstract: Thirty patients of medium (47 +/- 3) years of age with prosthetic bileaflet heart valves without any specific complications of the I-II functional classes and with the postoperative period after mitral (11) and aortal (19) valve replacements during (2.52 +/- 0.48) years were studied. The defects of coagulation and fibrinolytic systems were found in 9 patients with high prothrombin index (93.21 +/- 9.8)% and low INR (0.9-1.7). The activation of fibrinolysis, low platelets, hypofibrinogenemia, D-dimer which are the risk factors of thrombogenic complications were found in these patients. The updated turbo-dynamic express-method which helps to activate fibrinolysis in short terms and to make its correction is proposed.
authors.forename: T F
authors.initials: TF
authors.lastname: Subbotina
authors.forename: P I
authors.initials: PI
authors.lastname: Orlovskiĭ
authors.forename: N N
authors.initials: NN
authors.lastname: Petrishchev
authors.forename: V V
authors.initials: VV
authors.lastname: Gritsenko
authors.forename: D N
authors.initials: DN
authors.lastname: Doĭnikov
authors.forename: V P
authors.initials: VP
authors.lastname: Faenkova
authors.forename: T V
authors.initials: TV
authors.lastname: Vavilova
authors.forename: M I
authors.initials: MI
authors.lastname: Kandinskaia
authors.forename: D A
authors.initials: DA
authors.lastname: Polezhaev
mesh_terms: D001021:Aortic Valve; D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D003627:Data Interpretation, Statistical; D005260:Female; D005342:Fibrinolysis; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006487:Hemostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D009391:Nephelometry and Turbidimetry; D011516:Prothrombin / Q000032:analysis; D012307:Risk Factors; D013927:Thrombosis / Q000209:etiology; D013997:Time Factors
chemical_list: D011516:Prothrombin