[Combined effect of immobilization stress and gamma-irradiation on the blood-forming system in mice].
Experiments with mice BALB/C were aimed at studying effects of immobilization stress and consecutive total gamma-irradiation at the dose of 2.0 Gy. Disorders in the blood system were shown to be a function of phase of the general adaptation syndrome (GAS). Acute gamma-irradiation on the stage of GAS resistance inhibited adaptive and compensatory potentials of the blood-forming system, whereas chronic stress by itself increased the spontaneous rate of chromosomal aberrations in nucleus-containing bone marrow cells in experimental animals.
Muratova
M Iu
MIu
Vorozhtsov
S V
SV
Abrosimova
A N
AN
Kartashov
K V
KV
D000222:Adaptation, Physiological / Q000502:physiology; D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations; D005720:Gamma Rays; D007103:Immobilization; D007958:Leukocyte Count; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011833:Radiation Injuries, Experimental / Q000097:blood* / Q000150:complications*; D013158:Splenic Diseases / Q000209:etiology* / Q000503:physiopathology; D013315:Stress, Psychological / Q000097:blood*; D013952:Thymus Hyperplasia / Q000209:etiology* / Q000503:physiopathology