title: Hypercalcemia induced by parathyroid hormone-related peptide after treatment of carcinoma.
abstract: Squamous cell carcinoma of the head and neck is a rare cause of humoral hypercalcemia of malignancy. This paraneoplastic syndrome is usually one of the presenting symptoms of the disease. We report a case of squamous cell carcinoma of the oral cavity that presumably elaborated parathyroid hormone-related peptide (PTH-rP) and caused hypercalcemia only after radiotherapy and chemotherapy.
authors.affiliation: Department of Medicine, Huron Hospital, Cleveland Clinic Health System, OH 44112, USA.
authors.forename: Alina
authors.initials: A
authors.lastname: Gover
authors.forename: P Dileep
authors.initials: PD
authors.lastname: Kumar
authors.forename: Leon A
authors.initials: LA
authors.lastname: Brown
authors.forename: Keyvan
authors.initials: K
authors.lastname: Ravakhah
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D002294:Carcinoma, Squamous Cell / Q000378:metabolism* / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D009062:Mouth Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000628:therapy; D009384:Paraneoplastic Endocrine Syndromes / Q000209:etiology; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins / Q000378:metabolism*; D011878:Radiotherapy / Q000009:adverse effects
chemical_list: C470121:PTHLH protein, human; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins