title: Aggressive pituitary tumors in MEN1: do they refute the two-hit model of tumorigenesis?
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Marx
authors.forename: Lynnette K
authors.initials: LK
authors.lastname: Nieman
mesh_terms: D006801:Humans; D008954:Models, Biological; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications*; D010911:Pituitary Neoplasms / Q000150:complications* / Q000503:physiopathology*; D012720:Severity of Illness Index