title: [Extensive transbasal approach for removal of tumours in the nasal, sphenoid and clival regions].
abstract: OBJECTIVE
  To improve operative results of removal of the tumors in midline cranial base and the reconstruction of defect at frontal base through modification of the operative approach and techniques.
  
  
  METHODS
  Extensive transbasal approach was used in 15 patients with tumours in the nasal, sphenoid and clival regions.
  
  
  RESULTS
  The tumor was removed in 10 patients, near totally removed in 4 and partial removed in 1. The operative results of all patients were excellent except an elderly patient with mild operative morbidity.
  
  
  CONCLUSIONS
  The procedure we used expand the operative indications for the tumors situated at the midline cranial base and improve the operative results. The procedure has advantages such as wide operative space, reliable reconstruction of the frontal base, and no severe complications.
authors.affiliation: Department of Neurosurgery, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025.
authors.forename: J
authors.initials: J
authors.lastname: Shen
authors.forename: J
authors.initials: J
authors.lastname: Hu
authors.forename: B
authors.initials: B
authors.lastname: Hu
authors.forename: G
authors.initials: G
authors.lastname: Li
authors.forename: W
authors.initials: W
authors.lastname: Zhao
authors.forename: K
authors.initials: K
authors.lastname: Cheng
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: C
authors.initials: C
authors.lastname: Pu
authors.forename: Q
authors.initials: Q
authors.lastname: Sun
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D035262:Cranial Fossa, Anterior / Q000601:surgery; D003399:Craniotomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005626:Frontal Sinus / Q000601:surgery; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012888:Skull Neoplasms / Q000473:pathology / Q000601:surgery*; D013101:Sphenoid Sinus / Q000601:surgery