title: Multi-institutional experience with buccal mucosa onlay urethroplasty for bulbar urethral reconstruction.
abstract: OBJECTIVE
  Buccal mucosa has been advocated as an ideal graft material for urethral reconstruction. We report our multicenter experience with buccal mucosa ventral onlay urethroplasty for complex bulbar urethral reconstruction in adults.
  
  
  METHODS
  A retrospective analysis of patients who had undergone buccal onlay urethroplasty at 4 military medical treatment facilities participating in the Uniformed Services Urology Research Group was performed. The database generated included demographic data, genitourinary history, preoperative symptoms (American Urological Association symptom score), preoperative urinary flow rate, stricture length and operative statistics. Postoperative followup data included symptom score, flow rate, retrograde urethrogram results, and complications.
  
  
  RESULTS
  A total of 53 patients (average age 32 years, range 17 to 64) underwent buccal mucosa graft urethroplasty between January, 1996 and March, 1998 for refractory strictures. Sixteen patients had undergone an average of 2.2 prior endoscopic procedures (range 1 to 7). Average stricture length was 3.6 plus or minus standard deviation 1.8 cm. (range 2 to 7.5) as measured on preoperative retrograde urethrogram. Followup averaged 25 months (range 11 to 40 months). Average symptom scores decreased from 21.2 (range 14 to 33) preoperatively to 5.4 (range 3 to 8) postoperatively (p <0.001). Average peak urinary flow rates increased from 7.9 preoperatively to 30.1 ml. per second postoperatively (p <0.001). Postoperative retrograde urethrograms were available for 34 patients and were normal in 24. The overall complication rate was 5.4%. Three patients required endoscopic incisions. One patient has a recurrent narrowing and treatment is considered a failure. There were 4 sacculations (7.5%) and 6 narrowings, 3 of which required further treatment. Of the patients 50 required no additional procedures (94.3%).
  
  
  CONCLUSIONS
  Buccal mucosa grafts used as a ventral onlay for bulbar urethral reconstruction yield reproducibly excellent results with minimal morbidity and low complication rates. Longer followup will be required to confirm the durability of our results.
authors.affiliation: Department of Urology and Oral and Maxillofacial Surgery, Naval Medical Center, San Diego, San Diego, California 94121-0738, USA.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Kane
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Tarman
authors.forename: Duncan J
authors.initials: DJ
authors.lastname: Summerton
authors.forename: Craig E
authors.initials: CE
authors.lastname: Buchmann
authors.forename: John F
authors.initials: JF
authors.lastname: Ward
authors.forename: Keith J
authors.initials: KJ
authors.lastname: O'Reilly
authors.forename: Henry
authors.initials: H
authors.lastname: Ruiz
authors.forename: J Brantley
authors.initials: JB
authors.lastname: Thrasher
authors.forename: Burk
authors.initials: B
authors.lastname: Zorn
authors.forename: Carolyn
authors.initials: C
authors.lastname: Smith
authors.forename: Allen F
authors.initials: AF
authors.lastname: Morey
mesh_terms: D000293:Adolescent; D000328:Adult; D002610:Cheek; D006801:Humans; D008875:Middle Aged; D009061:Mouth Mucosa / Q000637:transplantation*; D019651:Plastic Surgery Procedures; D014521:Urethra / Q000601:surgery*; D014525:Urethral Stricture / Q000601:surgery*