title: Bullous eruptions caused by extravasation of mannitol--a case report.
abstract: Extravasation is one of the common complications seen with intravenous infusion. We bring forward a case of subcutaneous mannitol extravasation, which caused swelling and multiple cutaneous bullous eruptions in the hand and forearm during craniotomy. Treatment consisting of elevation of the affected extremity and application of silver sulfadiazine ointment twice daily to the injured area was successful. The possible mechanisms relevant to extravasation and its tissue damage are reviewed and discussed. Selecting proper intravenous infusion site, using pliable catheters and frequent inspection are important steps for prevention of extravasation.
authors.affiliation: First Department of Anesthesiology, Chang-Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan, R.O.C. kowaung@sinamail.com
authors.forename: K A
authors.initials: KA
authors.lastname: Chang
authors.forename: B
authors.initials: B
authors.lastname: Jawan
authors.forename: H N
authors.initials: HN
authors.lastname: Luk
authors.forename: S T
authors.initials: ST
authors.lastname: Fung
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000368:Aged; D003875:Drug Eruptions / Q000209:etiology* / Q000628:therapy; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications*; D005260:Female; D006801:Humans; D008353:Mannitol / Q000009:adverse effects*
chemical_list: D008353:Mannitol