[Update on differenciated thyroid carcinoma].
Differenciated thyroid carcinomas are the most frequently encountered endocrine tumours. These hormono-dependent carcinomas have a good prognosis. Data derived from molecular biology allowed a better understanding of pathophysiological mechanisms involved in tumorigenesis of thyroid papillar and follicular carcinomas. The use of the works derived from molecular biology also allowed a better diagnostic and therapeutic management of the thyroid cancer patients, particularly using recombinant human TSH. Familial thyroid cancer disease must also be recognised to optimise the clinical managemet of patients and their family.
Karayan
Lucie
L
Service d'endocrinologie-diabétologie, CHU, BP 577, 86021 Poitiers Cedex.
Hadjadj
Samy
S
Larsen
Christian J
CJ
Maréchaud
Richard
R
Kraimps
Jean-Louis
JL
D018263:Adenocarcinoma, Follicular / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics*; D000943:Antigens, Differentiation / Q000378:metabolism; D002291:Carcinoma, Papillary / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics*; D018797:Cell Cycle Proteins / Q000502:physiology; D016193:G1 Phase / Q000235:genetics; D037502:Galectin 3; D016147:Genes, Tumor Suppressor / Q000502:physiology; D006801:Humans; D019656:Loss of Heterozygosity; D009154:Mutation; D009361:Neoplasm Invasiveness; D009363:Neoplasm Proteins / Q000378:metabolism; D011519:Proto-Oncogenes / Q000235:genetics*; D011989:Receptors, Thyrotropin / Q000502:physiology; D011994:Recombinant Proteins; D019098:Telomerase / Q000502:physiology; D016615:Telomere / Q000502:physiology; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics*; D013972:Thyrotropin / Q000502:physiology
D000943:Antigens, Differentiation; D018797:Cell Cycle Proteins; D037502:Galectin 3; D009363:Neoplasm Proteins; D011989:Receptors, Thyrotropin; D011994:Recombinant Proteins; D013972:Thyrotropin; D019098:Telomerase