[Severe hypokalemia with paralysis in a patient with distal renal tubular acidosis as an initial expression of Sjögren's syndrome].
In a 33-year-old woman with a recent flaccid paralysis of the arms and legs, laboratory tests demonstrated a severe hypokalemia with hyperchloremic metabolic acidosis and abnormally acidified urine. The urinary anion gap was positive in the presence of acidosis, thus establishing the diagnosis of distal renal tubular acidosis. The patient made a full recovery after potassium and alkali replacement. Further investigation revealed Sjögren's syndrome as the underlying cause.
van Daele
P L A
PL
Afd. Inwendige Geneeskunde, Erasmus Medisch Centrum, Dr. Molewaterplein 40, 3015 GD Rotterdam. vandaele@inw3.azr.nl
Zanen
A L
AL
de Ronde
W
W
de Vries-Sluijs
T E M S
TE
Hayes
D P
DP
D000136:Acid-Base Equilibrium; D000141:Acidosis, Renal Tubular / Q000175:diagnosis / Q000209:etiology*; D000328:Adult; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000175:diagnosis / Q000209:etiology*; D009123:Muscle Hypotonia; D010243:Paralysis / Q000209:etiology*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis