title: Synthesis and interaction with copper(II) cations of cyano- and aminoresorcin[4]arenes.
abstract: Following our studies on resorcin[4]arenes, we synthesized new macrocycles containing cyanomethyl and aminomethyl side chains. Three stereoisomers (2a-c) of the former were obtained by BF3*Et2O tetramerization of the corresponding trans-cinnamic acid derivative and were shown to be in the 1,2-alternate, cone, and 1,3-alternate conformations. Conversely, the tetraamino derivative 6a in the cone conformation was prepared from the corresponding tetrabromide 3a. The interactions with Cu(II) cations of the new compounds were analyzed by measurements of 1H NMR and EPR spectra in parallel with molecular modeling calculations.
authors.affiliation: Dip. di Studi di Chimica e Tecnologia delle Sostanze Biologicamente Attive, Università La Sapienza, P. le A. Moro 5, I-00185 Roma, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Botta
authors.forename: Giuliano
authors.initials: G
authors.lastname: Delle Monache
authors.forename: Giovanni
authors.initials: G
authors.lastname: Zappia
authors.forename: Domenico
authors.initials: D
authors.lastname: Misiti
authors.forename: Maria Camilla
authors.initials: MC
authors.lastname: Baratto
authors.forename: Rebecca
authors.initials: R
authors.lastname: Pogni
authors.forename: Eszter
authors.initials: E
authors.lastname: Gacs-Baitz
authors.forename: Maurizio
authors.initials: M
authors.lastname: Botta
authors.forename: Federico
authors.initials: F
authors.lastname: Corelli
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Manetti
authors.forename: Andrea
authors.initials: A
authors.lastname: Tafi