title: Outbreak of nosocomial sepsis and pneumonia in a newborn intensive care unit by multiresistant extended-spectrum beta-lactamase-producing Klebsiella pneumoniae: high impact on mortality.
abstract: We describe a case-control study of a small outbreak of nosocomial sepsis and pneumonia with high mortality due to clonal dissemination of a multiresistant Klebsiella pneumoniae in the neonatal intensive care unit of a Mexican institution. Our study helped to change nosocomial infection control policy in this hospital.
authors.affiliation: Unidad de Investigación Médica en Epidemiología Clínica, Hospital Regional de Zona No. 1, Insituto Mexicano del Seguro Social, Durango.
authors.forename: G
authors.initials: G
authors.lastname: Martinez-Aguilar
authors.forename: C M
authors.initials: CM
authors.lastname: Alpuche-Aranda
authors.forename: C
authors.initials: C
authors.lastname: Anaya
authors.forename: D
authors.initials: D
authors.lastname: Alcantar-Curiel
authors.forename: C
authors.initials: C
authors.lastname: Gayosso
authors.forename: C
authors.initials: C
authors.lastname: Daza
authors.forename: C
authors.initials: C
authors.lastname: Mijares
authors.forename: J C
authors.initials: JC
authors.lastname: Tinoco
authors.forename: J I
authors.initials: JI
authors.lastname: Santos
mesh_terms: D016022:Case-Control Studies; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality*; D004196:Disease Outbreaks; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D007710:Klebsiella Infections / Q000188:drug therapy / Q000453:epidemiology / Q000401:mortality*; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000302:isolation & purification*; D018410:Pneumonia, Bacterial / Q000188:drug therapy / Q000453:epidemiology / Q000401:mortality*; D018805:Sepsis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality*; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001618:beta-Lactamases