Successful low-dose intracavitary irradiation of a Rathke's cleft cyst with colloidal rhenium-186.
Symptomatic recurrence of an histologically verified intra- and suprasellar Rathke's cleft cyst (RCC) was observed 4 months following transsphenoidal microsurgery. The space-occupying cyst was treated by endocavitary irradiation with colloidal rhenium-186 via a previously implanted catheter with an attached subcutaneous reservoir. The calculated dose of 4.4 Gy was able to stop the production of cyst fluid. Follow-up after intracavitary irradiation extends over 13 months. The cyst, with an initial size of 3 x 3 x 4 cm, has been reduced to 1.1 x 1.06 x 1.2 cm. The production of cyst fluid has decreased from 25 - 30 ml within 2 months before treatment to zero. The patient's visual and mental status as well as her quality of life are normal.
Moringlane
J R
JR
Department of Neurosurgery and Nuclear Medicine, University of the Saarland, 66421 Homburg/Saar, Germany.
Alexander
C
C
Kirsch
C M
CM
D001918:Brachytherapy / Q000379:methods*; D002404:Catheterization; D020863:Central Nervous System Cysts / Q000532:radiotherapy*; D003102:Colloids; D005260:Female; D006801:Humans; D008603:Mental Health; D008875:Middle Aged; D011788:Quality of Life; D011868:Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D012211:Rhenium / Q000008:administration & dosage / Q000627:therapeutic use*; D013238:Stereotaxic Techniques; D016896:Treatment Outcome; D014792:Visual Acuity
D003102:Colloids; D011868:Radioisotopes; D012211:Rhenium