[Surgery for lung cancer complicated by bronchial asthma].
OBJECTIVE
To assess surgery for lung cancer complicated by bronchial asthma.


METHODS
Lung hilum denervation was performed for asthma during radical resection of lung cancer. One patient with peripheral bronchogenic carcinoma in the right upper lobe underwent upper lobectomy and extensive dissection of lymph-nodes. Simultaneously, lung hilum denervation was done by complete amputation of the sympathetic and parasympathetic nerves around the lung hilum. Another patient with central bronchogenic carcinoma in the left upper lobe underwent lung autotransplantation. Pneumonectomy was performed, and the tumor parts of the lung were resected subsequently and the preservable parts of the lung were replanted into the bed of the upper lobe.


RESULTS
Follow-up showed that the two patients had been alive with tumor free for 80 months and 17 months respectively and the time of postoperative mechanical ventilation was 4 and 18 hours. The frequency of asthma paroxysm decreased and the severity attenuated. Parameters of blood gas and lung function were improved.


CONCLUSIONS
The poor lung function caused by asthma should not be regarded as a contradiction for the removal of lung cancer. Complete denervation around the lung hilum during the radical resection of lung cancer may contribute to the better treatment of lung cancer and asthma.
Liu
J
J
Department of Thoracic Surgery, People's Hospital, Beijing Medical University, Beijing 100044, China.
Zhang
G
G
Jiang
G
G
Peng
J
J
Wang
D
D
He
Q
Q
D000368:Aged; D001249:Asthma / Q000150:complications / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000601:surgery*; D016040:Lung Transplantation; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy / Q000379:methods; D013562:Sympathectomy; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014628:Vagotomy