title: [Effect of escharectomy during burn shock stage on stress response].
abstract: OBJECTIVE
  To investigate changes in hormones of plasma and the effect of escharectomy during burn shock stage on early stress response after burn.
  
  
  METHODS
  Sixteen male minipigs were subjected to a 35% TBSA III degree burn injury. The burned minipigs were randomly divided into two groups: escharectomy during burn shock stage group (S group) and escharectomy group after burn shock stage (N group). The sequential changes in plasma levels of insulin, glucagon, cortisol, GH, IGF-I, albumin were analyzed.
  
  
  RESULTS
  The serum concentration of insulin, glucagon, cortisol increased to some degree, whereas the serum concentration of GH, IGF-I decreased obviously after burn. As compared with the N group, no significant difference in the serum concentration of glucagon, cortisol, GH, IGF-I, was observed.
  
  
  CONCLUSIONS
  Escharectomy during burn shock stage could not aggravate stress response after burn.
authors.affiliation: Burn Institute, 304th Hospital, People's Liberation Army, Beijing 100037.
authors.forename: D
authors.initials: D
authors.lastname: Hao
authors.forename: Z
authors.initials: Z
authors.lastname: Guo
authors.forename: J
authors.initials: J
authors.lastname: Chai
authors.forename: L
authors.initials: L
authors.lastname: He
authors.forename: Z
authors.initials: Z
authors.lastname: Sheng
mesh_terms: D000818:Animals; D002056:Burns / Q000097:blood* / Q000601:surgery; D005934:Glucagon / Q000097:blood; D013006:Growth Hormone / Q000097:blood*; D007328:Insulin / Q000097:blood; D007334:Insulin-Like Growth Factor I / Q000378:metabolism*; D008297:Male; D011897:Random Allocation; D012774:Shock, Traumatic / Q000097:blood* / Q000601:surgery; D016038:Skin Transplantation; D013312:Stress, Physiological / Q000097:blood*; D013552:Swine; D013556:Swine, Miniature
chemical_list: D007328:Insulin; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone; D005934:Glucagon