title: [Update on differenciated thyroid carcinoma].
abstract: Differenciated thyroid carcinomas are the most frequently encountered endocrine tumours. These hormono-dependent carcinomas have a good prognosis. Data derived from molecular biology allowed a better understanding of pathophysiological mechanisms involved in tumorigenesis of thyroid papillar and follicular carcinomas. The use of the works derived from molecular biology also allowed a better diagnostic and therapeutic management of the thyroid cancer patients, particularly using recombinant human TSH. Familial thyroid cancer disease must also be recognised to optimise the clinical managemet of patients and their family.
authors.affiliation: Service d'endocrinologie-diabétologie, CHU, BP 577, 86021 Poitiers Cedex.
authors.forename: Lucie
authors.initials: L
authors.lastname: Karayan
authors.forename: Samy
authors.initials: S
authors.lastname: Hadjadj
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Larsen
authors.forename: Richard
authors.initials: R
authors.lastname: Maréchaud
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Kraimps
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics*; D000943:Antigens, Differentiation / Q000378:metabolism; D002291:Carcinoma, Papillary / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics*; D018797:Cell Cycle Proteins / Q000502:physiology; D016193:G1 Phase / Q000235:genetics; D037502:Galectin 3; D016147:Genes, Tumor Suppressor / Q000502:physiology; D006801:Humans; D019656:Loss of Heterozygosity; D009154:Mutation; D009361:Neoplasm Invasiveness; D009363:Neoplasm Proteins / Q000378:metabolism; D011519:Proto-Oncogenes / Q000235:genetics*; D011989:Receptors, Thyrotropin / Q000502:physiology; D011994:Recombinant Proteins; D019098:Telomerase / Q000502:physiology; D016615:Telomere / Q000502:physiology; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000235:genetics*; D013972:Thyrotropin / Q000502:physiology
chemical_list: D000943:Antigens, Differentiation; D018797:Cell Cycle Proteins; D037502:Galectin 3; D009363:Neoplasm Proteins; D011989:Receptors, Thyrotropin; D011994:Recombinant Proteins; D013972:Thyrotropin; D019098:Telomerase