Inverse planning and intensity-modulated radiotherapy in patients with prostate cancer.
Inverse planning and IMRT are methods with the potential to improve substantially clinical results in radiotherapy of prostate cancer. Available early clinical data demonstrate the feasibility and safety of high-dose IMRT for patients with localized prostate cancer and provide a proof-of-principle that this method improves dose conformality relative to tumor coverage and exposure to normal tissues.
Debus
Jürgen
J
Radiologische Klinik, Universitätsklinikum Heidelberg, Deutsches Krebsforschungszentrum (dkfz), Heidelberg, Deutschland. j.debus@dkfz.de
Zierhut
Dietmar
D
Didinger
Bernd
B
Schlegel
Wolfgang
W
Wannenmacher
Michael
M
D000230:Adenocarcinoma / Q000532:radiotherapy*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000379:methods*