title: [Language abnormalities in patients with multiple sclerosis].
abstract: BACKGROUND
  Patients suffering from multiple sclerosis (MS) have a high frequency of cognitive deficits. Research has demonstrated impairments in memory, attention, information-processing speed, and executive functions. Although it has been traditionally held that language function is commonly preserved in MS, some studies have demonstrated language impairment in these patients, particularly in tasks of naming and word-generation.
  
  
  OBJECTIVE
  The aim of the study was to examine language functioning in MS, with particular interest in naming ability and verbal fluency.
  
  
  METHODS
  Thirty patients with MS, and 30 neurologically intact normal controls, matched for age and educational level were evaluated. As part of a wider neuropsychological evaluation, all subjects were administered the Boston Naming Tests. To compare performances, a comprehensive classification of error types was devised.
  
  
  RESULTS
  MS patients showed significantly lower performance on both linguistic measures than the control subjects. On the Boston Naming Test, MS patients obtained significant lower scores than controls, with a high rate of semantic errors. Additionally, they tended to show an also high number of visuoperceptual errors. Low scores on naming task correlated with low performance on verbal fluency.
  
  
  CONCLUSIONS
  This study reveals that language function can be impaired in MS, and that naming difficulties are a frequent finding. This naming deficit seems to have a double origin, stemming from disruption at the levels of the perceptual and/or the semantic systems.
authors.affiliation: Servicio de Neurología, Hospital Británico de Buenos Aires, Argentina. drakem@ciudad.com.ar
authors.forename: M A
authors.initials: MA
authors.lastname: Drake
authors.forename: R F
authors.initials: RF
authors.lastname: Allegri
authors.forename: A
authors.initials: A
authors.lastname: Carrá
mesh_terms: D000328:Adult; D006801:Humans; D007806:Language Disorders / Q000209:etiology*; D009103:Multiple Sclerosis / Q000150:complications*; D009483:Neuropsychological Tests