title: Leukoderma acquisitum centrifugum. An unusual case.
abstract: A case is presented of a 9-year-old girl who developed a depigmented halo around a pigmented tumor of the skin on her shoulder. She also developed widespread metastases in the ipsilateral axillary lymph nodes, lungs, and, presumably, liver, and subsequently died of her disease. Histologic interpretations of the nature of the cutaneous tumor and axillary metastases are given and the suggestion made that the skin lesion was a malignant melanoma. Should this interpretation be correct, this case represents the first of its kind in which a lesion in a child with the clinical features of a halo nevus proved to be a fatal malignant melanoma.
authors.affiliation: Department of Laboratories, Long Island Jewish Hospital, New Hyde Park, NY, USA.
authors.forename: L
authors.initials: L
authors.lastname: Shapiro
authors.forename: A W
authors.initials: AW
authors.lastname: Kopf
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000473:pathology*; D008545:Melanoma / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*