title: Synchronous rectal and esophageal cancer associated with prurigo chronica multiformis: report of a case.
abstract: The skin lesions that appear in association with internal malignancies are called dermadromes or paraneoplastic cutaneous disorders. These skin changes characteristically develop with progression of the internal malignancy. A 75-year-old Japanese man who had been diagnosed as having prurigo chronica multiformis, a form of dermadrome, 5 years previously was referred to our hospital for further investigation. On admission, numerous itchy red papules were present on the right side of the abdomen and the inner aspect of both thighs. Intensive screening for internal malignancies revealed advanced rectal cancer and early esophageal cancer. After surgical resection, the skin lesions improved without any treatment. To the best of our knowledge, this is the first case of synchronous double cancers associated with prurigo chronica multiformis.
authors.affiliation: Department of Surgery, Osaka National Hospital, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Motoori
authors.forename: T
authors.initials: T
authors.lastname: Tsujinaka
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
authors.forename: K
authors.initials: K
authors.lastname: Fujitani
authors.forename: N
authors.initials: N
authors.lastname: Kikkawa
mesh_terms: D000368:Aged; D002908:Chronic Disease; D003082:Colectomy; D004938:Esophageal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D016629:Esophagectomy; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000601:surgery; D011536:Prurigo / Q000209:etiology*; D012004:Rectal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D012075:Remission, Spontaneous