title: [Long-term results of surgery for type A acute aortic dissection].
abstract: The cases of 160 patients (126 men, mean age 57.5 +/- 13.3 years) operated consecutively as an emergency for a Stanford type A dissection of the aorta between 1980 and 2000 were reviewed. The cumulative follow-up was 716.7 patient-years with an average follow-up of 4.51 +/- 5.6 patient-years. The risk factors for early postoperative mortality (up to 3 months), late mortality (> 3 months) and reoperation (cardiac and/or vascular) were determined by multivariate analysis. The hospital mortality was 27.5%. Older ages, obesity, previous cardiac surgery, preoperative shock, medullary, renal or mesenteric ischaemia were significant risk factors for early mortality. The probability of actuarial survival was 66.1 +/- 3.8%, 57.7 +/- 4.2%, 52.2 +/- 4.6% and 45.3 +/- 5.5% respectively at 1, 5, 10 and 15 years. Chronic obstructive airways disease and a more recent operation date were significant risk factors for late mortality. Thirty patients underwent 37 reoperations after an average of 5.7 +/- 4.5 years. The actuarial probability for no reoperation was 96.9 +/- 1.8%, 74.7 +/- 5.3%, 60.8 +/- 6.8% and 39.3 +/- 9.1% at 1, 5, 10 and 15 years respectively. The presence of severe preoperative aortic regurgitation was the only significant risk factor for reoperation. Type A acute dissection of the aorta continues to have a high early mortality and a significant incidence of late complications. Patients with severe aortic regurgitation before surgery are at high risk for reoperation and should probably have more radical aortic repair at the initial operation.
authors.affiliation: Service de chirurgie thoracique et cardiovasculaire, hôpital Henri Mondor, 51 avenue du Mal de Lattre de Tassigny, 94010 Créteil.
authors.forename: M
authors.initials: M
authors.lastname: Kirsch
authors.forename: C
authors.initials: C
authors.lastname: Soustelle
authors.forename: R
authors.initials: R
authors.lastname: Houël
authors.forename: M L
authors.initials: ML
authors.lastname: Hillion
authors.forename: D
authors.initials: D
authors.lastname: Thébert
authors.forename: B
authors.initials: B
authors.lastname: Alimoussa
authors.forename: D
authors.initials: D
authors.lastname: Loisance
mesh_terms: D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D001014:Aortic Aneurysm / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011183:Postoperative Complications; D012307:Risk Factors; D016019:Survival Analysis; D016896:Treatment Outcome