title: Carcinomatous meningitis as a clinical manifestation of pancreatic carcinoma.
abstract: Carcinomatous meningitis (CM) is clinically less common than brain metastasis or spinal cord compression, having dire consequences for both the quality of life and the overall survival of patients with solid tumors. It occurs in about 5% of all adult cancer patients, but autopsies may double this number. If leukemia and lymphoma are excluded, most cases are due to breast cancer, lung cancer and melanoma. In this report, we describe a 49-year-old male patient with metastatic pancreatic adenocarcinoma who developed carcinomatous meningitis. To our knowledge, this is only the second case of carcinomatous meningitis secondary to a pancreatic carcinoma described so far.
authors.affiliation: Chemotherapy Unit, Jules Bordet Institute, Brussels, Belgium. fabiano.ferreira@bordet.be
authors.forename: A F
authors.initials: AF
authors.lastname: Ferreira Filho
authors.forename: F
authors.initials: F
authors.lastname: Cardoso
authors.forename: A
authors.initials: A
authors.lastname: Di Leo
authors.forename: A
authors.initials: A
authors.lastname: Awada
authors.forename: V D
authors.initials: VD
authors.lastname: da Silva
authors.forename: R B
authors.initials: RB
authors.lastname: Tovar
authors.forename: G
authors.initials: G
authors.lastname: Schwartsmann
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D008581:Meningitis / Q000188:drug therapy / Q000209:etiology* / Q000532:radiotherapy; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy