title: [Long-term therapeutic effects of extended radical resection and radical resection of cancer of cardia and stomach fundus].
abstract: OBJECTIVE
  To study the best range of radical resection in the treatment of cancer of the cardia and fundus of stomach.
  
  
  METHODS
  418 patients with cancer of the cardia and fundus of stomach underwent radical resection. Of them 192 were treated by extended radical resection (extended group), and 226 by radical resection (radical group). The 5-year and 10-year survival rates were followed up and compared in the two groups.
  
  
  RESULTS
  Analysis failed to demonstrate significant difference between the two operations for TNM stage I and II (P > 0.05). For stage III, however, the 5-year and 10-year survival rates in the extended group increased by 14.2% and 15.9% as compared with those in the radical group (P < 0.05). The two groups survival rates were similar for stage IV (P > 0.05).
  
  
  CONCLUSIONS
  To completely clean the lymph nodes of splenic hilus and artery and improve long-term survival rate, extended radical resection including spleen and body and tail of the pancreas should be recommended for stage III patients with cancer of the cardia and fundus of stomach when their serosa was involved or lymph node metastasis took place.
authors.affiliation: Department of Oncology, Affiliated Union Hospital, Fujian Medical University, Fuzhou 350001, China.
authors.forename: C
authors.initials: C
authors.lastname: Huang
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Lu
authors.forename: Z
authors.initials: Z
authors.lastname: Zheng
authors.forename: X
authors.initials: X
authors.lastname: Wu
authors.forename: G
authors.initials: G
authors.lastname: Guan
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: Z
authors.initials: Z
authors.lastname: Zheng
mesh_terms: D002299:Cardia; D013505:Digestive System Surgical Procedures; D005260:Female; D005743:Gastrectomy; D005748:Gastric Fundus; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate