title: [Detection of the cutaneous melanomas, their metastasis and relapses by scintigraphies with 99MTC-HMPAO].
abstract: A pilot study was carried out in the Nuclear Medicine Department of the National Institute of Oncology and Radiobiology to learn the diagnostic efficacy of the 99mTc-HMPAO scintigraphy in the detection of cutaneous melanoma, distant and local metastases, in patients with a confirmed histological diagnosis. The planar and/or SPECT scintigraphy was performed in 17 patients and revealed 90% sensitivity for the detection of the disease. We calculated the tumor/background index in all the images obtained and found a value greater than 1 in every case. Thus, we can affirm that the 99mTc-HMPAO accumulation in tumors was higher than the background in all cases. We recommend that this procedure be considered in the follow up of these patients as a new diagnostic method which is very useful in the determination of the patient stage and prognostic evaluation.
authors.affiliation: Departamento de Medicina Nuclear, Instituto Nacional de Oncología y Radiobiología, Ciudad de La Habana, Cuba.
authors.forename: A A
authors.initials: AA
authors.lastname: Collazo De La Maza
authors.forename: M C
authors.initials: MC
authors.lastname: Borrón Molino
authors.forename: W
authors.initials: W
authors.lastname: Quesada Cepero
authors.forename: M
authors.initials: M
authors.lastname: Rebustillo
authors.forename: V
authors.initials: V
authors.lastname: León Landín
authors.forename: I
authors.initials: I
authors.lastname: Sánchez Monzón
authors.forename: R M
authors.initials: RM
authors.lastname: Ortiz
authors.forename: B
authors.initials: B
authors.lastname: Oliver
authors.forename: M
authors.initials: M
authors.lastname: Abreu
authors.forename: J P
authors.initials: JP
authors.lastname: Oliva González
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000000981:diagnostic imaging*; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D010865:Pilot Projects; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D019690:Technetium Tc 99m Exametazime