Synthetic studies of psilocin analogs having either a formyl group or bromine atom at the 5- or 7-position.
Psilocin analogs having either a formyl group (9-12) or a bromine atom (13-18) at the 5- or 7-position have been prepared for the first time. Syntheses of 5- and 7-bromo derivatives of 4-hydroxy- (23, 24, 28) and 4-benzyloxyindole-3-carbaldehyde (19, 25, 29, 30), 4-benzyloxyindole-3-acetonitriles (20, 31), and 4-benzyloxy-N,N-dimethyltryptamine (32, 34, 35) have also been established.
Yamada
Fumio
F
Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.
Tamura
Mayumi
M
Hasegawa
Atsuko
A
Somei
Masanori
M
D001966:Bromine / Q000737:chemistry*; D005561:Formates / Q000138:chemical synthesis* / Q000737:chemistry; D011562:Psilocybin / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry
D005561:Formates; C106724:oxomethylium; D011562:Psilocybin; C009105:psilocin; D001966:Bromine