An ecological risk assessment for spinosad use on cotton.
Spinosad is a reduced-risk insecticide with a novel mode of action that provides an alternative to older classes of insecticides such as organophosphates, carbamates and pyrethroids. A comprehensive ecological risk assessment for spinosad use in US cotton crops is presented within a framework of tiered levels of refinement following the guidelines of the US EPA for ecological risk assessments. Toxicity information for a variety of species is documented and utilized, environmental concentrations estimated, and risk characterizations in the form of risk quotients are quantified. Results indicate that spinosad use in cotton does not exceed the most conservative Tier I levels of concern (LOC) values for groundwater, mammals and birds or acute risk to aquatic organisms. Use of very conservative Tier I screening methods resulted in exceeding LOC values for chronic exposure for some aquatic organisms, thus prompting further refinement. When the exposure prediction was refined using less conservative, Tier II mechanistic environmental fate transport models to predict offsite transport and environmental concentrations, chronic risk was not predicted for these species. Spinosad is acutely toxic to bees under laboratory conditions, but toxicity of residue studies and field studies indicate that under actual use conditions the impact on bees is minimal.
Cleveland
Cheryl B
CB
Dow AgroSciences, 9330 Zionsville Rd, Indianapolis, IN 46268, USA. cbcleveland@dowagro.com
Mayes
Monte A
MA
Cryer
Steven A
SA
D000818:Animals; D000835:Animals, Wild; D003411:Arvicolinae; D001516:Bees / Q000187:drug effects; D001717:Birds; D002240:Carbohydrate Sequence; D003621:Daphnia / Q000187:drug effects; D004338:Drug Combinations; D004784:Environmental Monitoring / Q000379:methods*; D005399:Fishes; D005618:Fresh Water / Q000737:chemistry; D003368:Gossypium / Q000187:drug effects*; D007313:Insecta / Q000187:drug effects; D007306:Insecticides / Q000008:administration & dosage / Q000737:chemistry / Q000633:toxicity*; D007448:Invertebrates / Q000187:drug effects; D018942:Macrolides / Q000008:administration & dosage / Q000737:chemistry / Q000633:toxicity*; D008322:Mammals; D051379:Mice; D008954:Models, Biological; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009835:Oligochaeta / Q000187:drug effects; D010944:Plants / Q000187:drug effects; D018570:Risk Assessment / Q000379:methods*; D012788:Shrews; D023382:Toxicity Tests, Acute
D004338:Drug Combinations; D007306:Insecticides; D018942:Macrolides; C415329:spinosad