title: Autologous peripheral stem cell transplantation for aggressive hemophagocytic syndrome associated with T-cell lymphoma: case study and review.
abstract: Hemophagocytic syndrome (HPS) is a rare clinical presentation infrequently associated with lymphoproliferative disorders. We describe a 29-year-old male with aggressive HPS and T-cell lymphoma managed successfully with high-dose chemotherapy and autologous peripheral stem cell transplantation (APSCT), in remission at 41 months of follow-up. In reviewing the literature, this case illustrates the 2nd longest surviving individual post stem cell transplant for aggressive HPS.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
authors.forename: Davinder S
authors.initials: DS
authors.lastname: Jassal
authors.forename: Ken
authors.initials: K
authors.lastname: Kasper
authors.forename: Carmen
authors.initials: C
authors.lastname: Morales
authors.forename: Morel
authors.initials: M
authors.lastname: Rubinger
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D018380:Hematopoietic Stem Cell Transplantation; D015616:Histiocytosis, Non-Langerhans-Cell / Q000150:complications / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000150:complications*; D008297:Male; D012074:Remission Induction; D012867:Skin / Q000098:blood supply / Q000473:pathology; D013154:Spleen / Q000473:pathology; D013601:T-Lymphocytes / Q000473:pathology; D014182:Transplantation, Autologous