[Determination of triacontanol and octacosanol in fenglasu and fenglasu capsules by capillary gas chromatography].
OBJECTIVE
The method was established for the determination of triacontanol and octacosanol in fenglasu and fenglasu capsules.


METHODS
The solvent was chloroform. The internal standard was hexatriacontanol. Using SIMPLCITY-1 capillary column, flame ionization detector was specified, injector temperature was 300 degrees C, and the column temperature rise by programming. [Initial temperature was 240 degrees C, maintaining 1 min and then rising the temperature (5 degrees C.min-1) to 300 degrees C for 15 min]. The flow rate of Nitrogen was 27 ml.min-1.


RESULTS
The calibration curves were linear in the range of 0.4-1.6 mg/ml for triacontanol(r = 0.999), 0.2-0.6 mg/ml for octacosanol(r = 0.9996) respectively. The average recovery (n = 9) was 99.2% for triacontanol (RSD = 1.15%), 99.91% for octacosanol (RSD = 1.40%).


CONCLUSIONS
The method is rapid, accurate and reliable for the quality control of fenglasu and fenglasu capsules.
Wang
S
S
Guangzhou Baiyunshan Pharmaceutical Factory, Guangzhou 510515.
Ye
F
F
D002214:Capsules; D002849:Chromatography, Gas; D005233:Fatty Alcohols / Q000032:analysis*; D008516:Medicine, Chinese Traditional / Q000592:standards*; D011786:Quality Control
D002214:Capsules; D005233:Fatty Alcohols; C047578:1-triacontanol; C044309:1-octacosanol