Topographical layout of hand, eye, calculation, and language-related areas in the human parietal lobe.
To identify subdivisions of the human parietal cortex, we collected fMRI data while ten subjects performed six tasks: grasping, pointing, saccades, attention, calculation, and phoneme detection. Examination of task intersections revealed a systematic anterior-to-posterior organization of activations associated with grasping only, grasping and pointing, all visuomotor tasks, attention and saccades, and saccades only. Calculation yielded two distinct activations: one unique to calculation in the bilateral anterior IPS mesial to the supramarginal gyrus and the other shared with phoneme detection in the left IPS mesial to the angular gyrus. These results suggest human homologs of the monkey areas AIP, MIP, V6A, and LIP and imply a large cortical expansion of the inferior parietal lobule correlated with the development of human language and calculation abilities.
Simon
Olivier
O
Unité INSERM 334, IFR 49, Service Hospitalier Frédéric Joliot, CEA/DSV, Orsay, France.
Mangin
Jean François
JF
Cohen
Laurent
L
Le Bihan
Denis
D
Dehaene
Stanislas
S
D000328:Adult; D000818:Animals; D001288:Attention / Q000502:physiology; D001931:Brain Mapping; D003071:Cognition / Q000502:physiology*; D005260:Female; D000882:Haplorhini; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D008953:Models, Anatomic; D009068:Movement / Q000502:physiology*; D010296:Parietal Lobe / Q000033:anatomy & histology* / Q000502:physiology*; D012438:Saccades; D013850:Thinking / Q000502:physiology*