title: [Prediction and diagnosis of drug intolerance in patients with purulent infection and burn disease].
abstract: The immunological study was made in which the drug sensitivity index according to S. M. Demyanenko was estimated in 76 patients (24 women and 52 men aged 17-73 years): in patients with soft tissue purulent infection (group 1, n = 46) and surface thermal burns (degree III-IV) of 40% body surface (group 2, n = 30). Patients with satisfactory drug tolerance served control (16 patients of group 1 and 10 ones of group 2). Correlations between humoral and cellular immunity parameters and drug sensitivity index were studied. The results may serve a basis for development of early and adequate correction of immunological disorders in the above patients, of drug-related complications caused by immunological imbalance.
authors.forename: L V
authors.initials: LV
authors.lastname: Elagina
authors.forename: A M
authors.initials: AM
authors.lastname: Svetukhin
authors.forename: A A
authors.initials: AA
authors.lastname: Alekseev
authors.forename: L A
authors.initials: LA
authors.lastname: Blatun
authors.forename: M G
authors.initials: MG
authors.lastname: Krutikov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002056:Burns / Q000188:drug therapy*; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013492:Suppuration
chemical_list: D000900:Anti-Bacterial Agents