Molecular analysis of HLA-DRB1 polymorphism in north-east Spain.
The DRB1* polymorphism in 941 randomly selected individuals from the Umbilical Cord Blood Bank of Barcelona (92.75% of Spanish origin) was determined by sequence-based typing. The HLA profile was similar to that of other Mediterranean populations, with DRB1*0701 and *0301 being the most frequent alleles. This may be a consequence of the mixture of alleles as a result of migration from contiguous geographical areas.
Vidal
S
S
Department of Immunology, Hospital Sant Pau and Institute Rec. Sant Pau, Pare Claret 167, Barcelona 08025, Spain. Svidal@hsp.santpau.es
Morante
M P
MP
Moga
E
E
Mosquera
A M
AM
Querol
S
S
Garcia
J
J
Rodriguez-Sanchez
J l
Jl
D000483:Alleles; D005787:Gene Frequency; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D011110:Polymorphism, Genetic; D013030:Spain
D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains