title: [Experimental study of osseointegrated dental implants placed into fresh extraction sockets in dogs].
abstract: OBJECTIVE
  To investigate the better way in treating bone defects around implants.
  
  
  METHODS
  12 mongrel dogs, pure titanium implants were immediately inserted in the mesial roots of the second, third and fourth mandibular premolar sockets. The defects around implants were separately filled with demineralized freeze-dried bone allograft (DFDBA), demineralized freeze-dried allocancellous in combination with bBMP (bBMP compound bone) and nothing.
  
  
  RESULTS
  Histologic observation showed that bone defects around implants were substituted by new bone in DFDBA group at 12 weeks and in bBMP compound bone group at 8 weeks, and also the osseointegration were obtained between implants and bone, but bone defects were only filled about 3/5 in no graft group at 12 weeks.
  
  
  CONCLUSIONS
  Immediate implants could obtain good osseointegration if the defects around implants were treated properly and the right technique was used, and also the use of bBMP compound bone could promote obviously bone formation in defects around implants.
authors.affiliation: College of Stomatology, Fourth Military Medical University, Xi'an 710032.
authors.forename: B
authors.initials: B
authors.lastname: Lu
authors.forename: B
authors.initials: B
authors.lastname: Liu
authors.forename: Q
authors.initials: Q
authors.lastname: Sun
mesh_terms: D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use; D016025:Bone Transplantation; D002417:Cattle; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D004285:Dogs; D020007:Implants, Experimental; D008334:Mandible / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D008963:Molar / Q000601:surgery; D016348:Osseointegration / Q000187:drug effects; D014081:Tooth Extraction; D020390:Tooth Socket / Q000601:surgery*
chemical_list: D019485:Bone Morphogenetic Proteins; D015921:Dental Implants