title: Animal study on lung injury caused by simulant segmented shock waves.
abstract: OBJECTIVE
  To study the lung injury caused by segmented shock waves.
  
  
  METHODS
  A total of 60 rabbits and 20 rats were used in this study. The process of transmission of shock waves was divided into three phases, i.e., the recompression phase (RP), the decompression phase (DP) and the underpressure phase (UP). And the recompression wave (RW), the decompression wave (DW) a nd the underpressure wave (UW) simulated the three phases, respectively, generated by the equipment designed by us. The RW test, DW test and UW test were respectively applied to the animals. And lung injuries caused by segmented shock waves were discussed.
  
  
  RESULTS
  Under the experimental conditions, the RW did not cause obvious lung injury, but the DW could cause different severities of lung injuries. The greater the decompression ranged and the shorter the decompression duration was adopted, the more severe the lung injury was observed. The UW, to some extent, could cause obvious lung injury.
  
  
  CONCLUSIONS
  It suggests that lung injury under shock waves probably occurs during the DP primarily. It probably does not cause direct obvious lung injury during the RP, but significantly influences the capability of causing lung injury during the DP.
authors.affiliation: Research Institute of Surgery/Daping Hospital, Third Military Medical University, Chongqing 400042, China.
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: X
authors.initials: X
authors.lastname: Ning
authors.forename: H
authors.initials: H
authors.lastname: Xu
authors.forename: K
authors.initials: K
authors.lastname: Xiao
mesh_terms: D000818:Animals; D008096:Lithotripsy / Q000009:adverse effects*; D011312:Pressure; D011817:Rabbits; D051381:Rats; D012128:Respiratory Distress Syndrome / Q000209:etiology* / Q000503:physiopathology*; D015599:Trauma Severity Indices