title: Theta oscillations in the hippocampus.
abstract: Theta oscillations represent the "on-line" state of the hippocampus. The extracellular currents underlying theta waves are generated mainly by the entorhinal input, CA3 (Schaffer) collaterals, and voltage-dependent Ca(2+) currents in pyramidal cell dendrites. The rhythm is believed to be critical for temporal coding/decoding of active neuronal ensembles and the modification of synaptic weights. Nevertheless, numerous critical issues regarding both the generation of theta oscillations and their functional significance remain challenges for future research.
authors.affiliation: Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey and Neurological Institute of New Jersey, Newark, NJ 07102, USA. buzsaki@axon.rutgers.edu
authors.forename: György
authors.initials: G
authors.lastname: Buzsáki
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001683:Biological Clocks / Q000502:physiology; D018891:Dentate Gyrus / Q000502:physiology; D006624:Hippocampus / Q000166:cytology / Q000502:physiology*; D006801:Humans; D008959:Models, Neurological; D009473:Neuronal Plasticity / Q000502:physiology; D011950:Receptors, Cholinergic / Q000378:metabolism; D011963:Receptors, GABA-A / Q000378:metabolism; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism; D013826:Theta Rhythm
chemical_list: D011950:Receptors, Cholinergic; D011963:Receptors, GABA-A; D016194:Receptors, N-Methyl-D-Aspartate