title: Flow instabilities in a graft anastomosis: a study of the instantaneous velocity fields.
abstract: The major cause of arterial bypass graft failure is intimal hyperplasia. Fluctuating wall shear stresses in the graft, which are associated with disturbed flow, are believed to be important factors in the development and localization of intimal hyperplasia. This study, based upon water as the working fluid, has investigated the flow structure inside a 30 degree Y-junction with different fillet radii at the intersection between the graft and the host artery at various Reynolds numbers and distal outlet segment (DOS) to proximal outlet segment (POS) flow ratios. The structure of the flow has been investigated experimentally using particle image velocimetry (PIV). The two-dimensional instantaneous velocity fields confirm the existence of a very complex flow, especially in the toe and heel regions for the different fillet radii and clearly identify features such as sinks, sources, vortices and strong time dependency.
authors.affiliation: Division of Mechanical Engineering and Energy Studies, Cardiff School of Engineering, Cardiff University, Wales, UK.
authors.forename: C J
authors.initials: CJ
authors.lastname: Bates
authors.forename: D M
authors.initials: DM
authors.lastname: O'Doherty
authors.forename: D
authors.initials: D
authors.lastname: Williams
mesh_terms: D000714:Anastomosis, Surgical; D001783:Blood Flow Velocity / Q000502:physiology*; D001026:Coronary Artery Bypass; D006084:Graft Rejection; D006801:Humans; D006965:Hyperplasia; D017539:Tunica Intima / Q000473:pathology; D006113:United Kingdom