Effect of environmental deprivation on anxiety in rats.
Environmental deprivation (ED) induced a significant increase in open-field ambulation, rears, self-groomings, faecal pellets and decrease in activity in centre in Charles Foster albino rats of 30, 45 and 60 days age groups. In elevated plus maze, significant attenuation of open arm time/entries and augmentation of enclosed arm time/entries were noted in ED rats of all the three age groups. Similarly ED rats also showed significant decrease in time spent on open arms, entries, head dips and stretched attend postures in comparison to age matched rats reared under normal environmental conditions. The results indicate that imposition of environmental deprivation in rats' life consistently resulted in significant anxiogenic behaviour on all the tests. However, the anxiogenic effect of ED was less marked when it was imposed at 60th day of life in rats.
Jaiswal
A K
AK
Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. arunjais@rediffmail.com
D000818:Animals; D001007:Anxiety / Q000523:psychology*; D001522:Behavior, Animal / Q000502:physiology*; D005106:Exploratory Behavior / Q000187:drug effects*; D005260:Female; D008297:Male; D018782:Maze Learning; D009043:Motor Activity / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012934:Social Isolation / Q000523:psychology*