[Radionuclide pulmonary perfusion imaging in evaluating pulmonary hypertension in patients with congenital heart disease].
OBJECTIVE
To evaluate the degree of pulmonary hypertension in patients with congenital heart disease (CHD) by using radionuclide pulmonary perfusion imaging.


METHODS
The pulmonary perfusion in 81 patients with left to right cardiac shunts was examined by scintigram with macroaggregates of (99m)Tc-labeled human serum albumin (PPS). PPS was analyzed for (1) lung regional radionuclide count (LRC), (2) right upper and lower lung count ratio (RULR), (3) kidney count ratio (KCR). The results were compared with those of cardiac catheterization exam.


RESULTS
There were correlation between mean pulmonary arterial pressure (mPAP), total pulmonary resistance (TPR), and PPS (KCR, RULR with mPAP gamma = 0.25, 0.35; LRC, KCR with TPR gamma = -0.34, 0.29). Five patients repeated PPS test after early operation. There were no changes in PPS.


CONCLUSIONS
The degree of reversibility of pulmonary hypertension in patients with CHD could be quantitatively analysed by PPS.
Pan
S
S
Department of Cardiovascular Surgery, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing 100037.
Xiao
M
M
Liu
Y
Y
Hu
S
S
Shi
R
R
Liu
X
X
Yu
J
J
Li
S
S
Tian
Y
Y
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D007223:Infant; D008168:Lung / Q000098:blood supply / Q000000981:diagnostic imaging*; D008297:Male; D011651:Pulmonary Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin; D055815:Young Adult
D013668:Technetium Tc 99m Aggregated Albumin