title: Intracranial meningeal involvement in Churg-Strauss syndrome.
abstract: We describe the case of a 54-year-old woman with a clinical diagnosis of Churg-Strauss syndrome (CSS). The patient had a fever of unknown origin, severe headache, progressing left ophthalmoplegia, and visual acuity disturbance. MR imaging revealed diffuse and thick hypointense lesions on T2-weighted images in the frontal meninges and anterior falx cerebri with diffuse enhancement. Similar lesions were also detected in the left superior ophthalmic fissure to the cavernous sinus. Nodular lesions in the fourth ventricle, which might have been the cause of hydrocephalus, were hypointense on T2-weighted images. These MR imaging findings suggested remote granulomatous involvement in the meninges and choroid plexus associated with CSS. To our knowledge, remote meningeal involvement in association with CSS has not been previously reported.
authors.affiliation: Department of Radiology, National Defense Medical College, 3-2 Namiki-Cho, Tokorozawa City, Saitama, Japan 359-8513.
authors.forename: Aya M
authors.initials: AM
authors.lastname: Tokumaru
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Obata
authors.forename: Shinya
authors.initials: S
authors.lastname: Kohyama
authors.forename: Tatsumi
authors.initials: T
authors.lastname: Kaji
authors.forename: Hiromi
authors.initials: H
authors.lastname: Okizuka
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Suzuki
authors.forename: Shoichi
authors.initials: S
authors.lastname: Kusano
mesh_terms: D001921:Brain / Q000473:pathology*; D002426:Cavernous Sinus / Q000473:pathology; D002493:Central Nervous System Diseases / Q000150:complications / Q000175:diagnosis; D002831:Choroid Plexus / Q000473:pathology; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D020546:Fourth Ventricle / Q000473:pathology; D006099:Granuloma / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008578:Meninges / Q000473:pathology*; D008875:Middle Aged