[Maternal plasma and amniotic fluid interleukin-6 and tumor necrosis factor-alpha levels in imminent preterm labor].
METHODS
Our purpose was to investigate the maternal plasma and amniotic fluid interleukin-6 and tumor necrosis factor-alpha levels in women with imminent preterm labour.


METHODS
The present study was designed to evaluate IL-6 and TNF-alpha levels in 93 pregnant women with threatened preterm labour and 40 women with normal pregnancy. Maternal blood samples were collected by routine forearm venipuncture at admission during routine laboratory tests. Amniotic fluid was collected through hysterectomy during caesarean delivery from women at term but not in labour and by amniotomy or hysterectomy from women with preterm labour.


RESULTS
Maternal plasma and amniotic fluid IL-6 and TNF-alpha concentrations were significantly elevated in women with preterm labour (premature rupture of membranes and uterine contractions) compared to gestationally matched, non-labouring controls.
Bielecki
M
M
Klinika Połoznictwa Akademii Medycznej w Białymstoku.
Zdrodowska
J
J
Bielecki
D A
DA
Bodzenta-Łukaszyk
A
A
Jarocki
S
S
D000653:Amniotic Fluid / Q000276:immunology*; D016022:Case-Control Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000276:immunology; D006801:Humans; D015850:Interleukin-6 / Q000097:blood / Q000378:metabolism*; D007752:Obstetric Labor, Premature / Q000097:blood / Q000276:immunology*; D011247:Pregnancy; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha