Community-acquired bacteremic Acinetobacter pneumonia in tropical Australia is caused by diverse strains of Acinetobacter baumannii, with carriage in the throat in at-risk groups.
Acinetobacter isolates from eight subjects with community-acquired Acinetobacter pneumonia (CAAP), a major cause of fatal community-acquired pneumonia in tropical Australia, were phenotypically and genotypically confirmed by pulsed-field gel electrophoresis analysis to be broadly diverse Acinetobacter baumannii strains. Wet-season throat carriage of A. baumannii was found in 10% of community residents with excess levels of alcohol consumption, the major at-risk group for CAAP.
Anstey
Nicholas M
NM
Menzies School of Health Research, Royal Darwin Hospital, Northern Territory Clinical School, Darwin, Northern Territory, Australia. anstey@menzies.edu.au
Currie
Bart J
BJ
Hassell
Marilyn
M
Palmer
Didier
D
Dwyer
Brian
B
Seifert
Harald
H
D000150:Acinetobacter / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D000151:Acinetobacter Infections / Q000382:microbiology; D000428:Alcohol Drinking; D001315:Australia; D016470:Bacteremia / Q000382:microbiology*; D002353:Carrier State / Q000382:microbiology*; D017714:Community-Acquired Infections / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D010614:Pharynx / Q000382:microbiology*; D018410:Pneumonia, Bacterial / Q000382:microbiology*; D012307:Risk Factors; D014329:Tropical Climate