title: Complex karyotype in a low grade phyllodes tumor of the breast.
abstract: Cytogenetic analysis of a phyllodes tumor of low grade malignancy disclosed the karyotype 52-55,XX, -1,+5,+7,+9,+10,+11,-15,+18,-19,+20,der(21)t(1;21)(p13;q22),+mar1x 2-4,+mar2[cp18]/46,XX. This study shows that a complex chromosome karyotype can be found in low-grade phyllodes tumors and is not necessarily a sign of extreme malignancy of these neoplasms.
authors.affiliation: Department of Surgical Pathology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA. jladesich@kumc.edu
authors.forename: James
authors.initials: J
authors.lastname: Ladesich
authors.forename: Ivan
authors.initials: I
authors.lastname: Damjanov
authors.forename: Diane
authors.initials: D
authors.lastname: Persons
authors.forename: William
authors.initials: W
authors.lastname: Jewell
authors.forename: Teresa
authors.initials: T
authors.lastname: Arthur
authors.forename: Jennifer
authors.initials: J
authors.lastname: Rogana
authors.forename: Barbara
authors.initials: B
authors.lastname: Davoren
mesh_terms: D001706:Biopsy; D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D003557:Phyllodes Tumor / Q000235:genetics* / Q000473:pathology