Short synthesis of novel 9,11-secosterols.
Starting from ergosterol two novel 9,11-secosterols with modified side chains (1a) and (1c) were synthesized via eight main transformations.
Jäälaid
R
R
Institute of Chemistry at Tallinn Technical University, Estonia.
Järving
I
I
Pehk
T
T
Parve
O
O
Lille
U
U
D000818:Animals; D002175:Candida / Q000201:enzymology; D002453:Cell Cycle / Q000187:drug effects; D002855:Chromatography, Thin Layer; D003063:Cnidaria / Q000737:chemistry*; D004800:Enzymes, Immobilized; D005656:Fungal Proteins; D008049:Lipase / Q000378:metabolism; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012632:Secosteroids / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
C446956:24-nor-9,11-seco-11-acetoxy-3,6-dihydroxycholesta-7,22-dien-9-one; C446957:24-nor-9,11-seco-11-oxo-3,6-dihydroxycholesta-7,22-dien-9-one; D004800:Enzymes, Immobilized; D005656:Fungal Proteins; D012632:Secosteroids; C093667:Novozyme 435; D008049:Lipase