[Bacterial distribution and antimicrobial resistance monitoring of surgical infection].
OBJECTIVE
To study the antimicrobial resistance of surgical isolates in Wuhan area.


METHODS
The diameters of the inhibition zones of surgical isolates around antibiotic susceptibility test discs at 13 hospitals in Wuhan were computerfiled and analysed by the software of "WHONET-3" according to NCCLS published in 1993.


RESULTS
A total of 957 surgical isolates were collected in 1996. S. aureus, P. aeruginosa, E. coli and CNS were the main microorganisms. 12.4% of S. aureus was resistant to oxacillin and to other antimicrobials as well. Most strains of Enterobacteriaceae were resistant to ampicillin, with a resistant rate of more than 75%, but 93% for klebsiella sp. Imipenem, ceftazidime, amikacin and ciprofloxacin were most active agents against Gram (-) bacilli including Enterobacteriaceae and glucose nonfermenters.


CONCLUSIONS
Antimicrobial resistance should be seriously considered during surgical therapy and prophylaxis with antimicrobial agents. The tendency to antimicrobial resistance of clinical isolates should be followed up continuously.
Shen
Z
Z
Contagious Department, Tongji Hospital, Tongji Medical University, Wuhan 430030.
Wang
H
H
Song
P
P
Sun
Z
Z
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D002681:China; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D013530:Surgical Wound Infection / Q000382:microbiology*
D000900:Anti-Bacterial Agents