A new case of acute nonlymphocytic leukemia (French-American-British subtype M1) with double minutes and c-MYC amplification.
Herein, we present a new case of acute nonlymphocytic leukemia (ANLL) French-American-British M1 subtype with presence of multiple double minutes (dmin) derived from the amplification of the c-MYC oncogene. A review of dmins in ANLL is presented.
Rodon
Natàlia
N
Laboratori de Citogenètica i Biologia Molecular, Departament de Patologia, Hospital del Mar, IMAS, Barcelona, Spain.
Solé
Francesc
F
Espinet
Blanca
B
Salido
Marta
M
Zamora
Lourdes
L
Cigudosa
Juan Cruz
JC
Woessner
Soledad
S
Florensa
Lourdes
L
D000368:Aged; D000369:Aged, 80 and over; D002871:Chromosome Banding; D005260:Female; D005784:Gene Amplification; D016259:Genes, myc; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*