title: Recurrent pneumonia due to persistent Chlamydia pneumoniae infection.
abstract: Two cases of recurrent pneumonia due to Chlamydia pneumoniae are described. C. pneumoniae was continuously detected from the nasopharynx in both patients by the polymerase chain reaction and/or culture even with appropriate antibiotic therapy during the first episode. After eradication of C. pneumoniae with long-term macrolide therapy, the respiratory symptoms of both patients completely disappeared and no relapse was observed. These data indicate that new treatment strategies may be necessary to eradicate the organism in patients prone to persistent infection.
authors.affiliation: Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Miyashita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukano
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hara
authors.forename: Koichiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Niki
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Matsushima
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002690:Chlamydia Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D018942:Macrolides; D008297:Male; D018410:Pneumonia, Bacterial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D011859:Radiography; D012008:Recurrence; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides