Winging it--actin on the fly.
How actin dynamics might be regulated to generate specific cellular structures during development remains something of a mystery. New insights may be gained from the recent identification of a conserved cofilin phosphatase, Slingshot, which modulates actin dynamics to help control Drosophila wing hair morphogenesis.
Baum
Buzz
B
LICR, Department of Biochemistry and Molecular Biology, University College London, Gower Street, WC1E 6BT, London, United Kingdom.
D000199:Actins / Q000378:metabolism*; D000818:Animals; D004330:Drosophila / Q000196:embryology* / Q000235:genetics / Q000378:metabolism*; D029721:Drosophila Proteins / Q000378:metabolism*; D006197:Hair / Q000196:embryology / Q000378:metabolism; D008840:Microfilament Proteins / Q000378:metabolism; D009024:Morphogenesis; D009154:Mutation; D010766:Phosphorylation; D014921:Wings, Animal / Q000196:embryology* / Q000378:metabolism
D000199:Actins; D029721:Drosophila Proteins; D008840:Microfilament Proteins; C442839:twf protein, Drosophila