[Multiple subpial transection in surgical treatment of intractable epilepsy].
OBJECTIVE
To increase the effect of epilepsy surgery, we use multiple subpial transection (MST) clinically on the basis of experimental study.


METHODS
We analyzed the seizure type and course of 116 intractable epilepsy patients treated with MST and surgical technique were modified.


RESULTS
100 patients were followed up for 1 to 5 years. Complete control of seizure was obtained in 62 patients (62%), significant reduction (over 75%) in 20 (20%), reduction (over 50%) in 12 (12%), and no change in 6 (6%). The total effective rate was 94%, and the significant effective rate was 82%. No functional defect was found in any patients.


CONCLUSIONS
MST is a effective in surgical treatment of intractable epilepsy and can replace conventional methods. Combined bilateral frontal lobe MST and anterior callosotomy is a good way to treat intractable generalized epilepsy.
Zhao
Q
Q
Neurosurgical Center of Navy General Hospital, Chinese People's Liberation Army, Beijing 100037.
Liu
Z
Z
Li
S
S
Tian
Z
Z
Liu
J
J
Cui
Y
Y
Lin
H
H
Guan
X
X
D000293:Adolescent; D000328:Adult; D002648:Child; D004827:Epilepsy / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*