The art and design of genetic screens: Arabidopsis thaliana.
Molecular genetic studies rely on well-characterized organisms that can be easily manipulated. Arabidopsis thaliana--the model system of choice for plant biologists--allows efficient analysis of plant function, combining classical genetics with molecular biology. Although the complete sequence of the Arabidopsis genome allows the rapid discovery of the molecular basis of a characterized mutant, functional characterization of the Arabidopsis genome depends on well-designed forward genetic screens, which remain a powerful strategy to identify genes that are involved in many aspects of the plant life cycle.
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Damian R
DR
Institute of Plant Biology, University of Zürich, Zollikerstrasse 107, CH-8008 Zürich, Switzerland.
Grossniklaus
Ueli
U
D000483:Alleles; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development; D015870:Gene Expression; D017930:Genes, Reporter; D005818:Genetic Engineering; D014644:Genetic Variation; D018745:Genome, Plant; D008957:Models, Genetic; D008967:Molecular Biology; D016254:Mutagenesis, Insertional; D009154:Mutation; D010641:Phenotype; D030821:Plants, Genetically Modified