6-Aminopyridine-3-thiol.
The title compound, C(5)H(6)N(2)S, is a simple but novel pyridinethiol of pharmacological interest. The molecule is planar. The crystal packing is dominated by hydrophobic contacts and a pair of hydrogen-bond interactions between the amino group of one pyridine molecule and the ring N atom of a neighbouring base, stabilizing the structure.
Sabino
J R
JR
Instituto de Física de São Carlos, Universidade de São Paulo, Av. Trabalhador Sancarlense 400, Caixa Postal 369, CEP 13560-970, São Carlos SP, Brazil. jrsabino@if.sc.usp.br
da Silva
C H T P
CH
Yonashiro
M
M
D000631:Aminopyridines / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D012556:Schistosomicides / Q000138:chemical synthesis / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D014344:Trypanocidal Agents / Q000138:chemical synthesis / Q000737:chemistry*
C454604:6-aminopyridine-3-thiol; D000631:Aminopyridines; D012556:Schistosomicides; D013438:Sulfhydryl Compounds; D014344:Trypanocidal Agents