Complex karyotype in a low grade phyllodes tumor of the breast.
Cytogenetic analysis of a phyllodes tumor of low grade malignancy disclosed the karyotype 52-55,XX, -1,+5,+7,+9,+10,+11,-15,+18,-19,+20,der(21)t(1;21)(p13;q22),+mar1x 2-4,+mar2[cp18]/46,XX. This study shows that a complex chromosome karyotype can be found in low-grade phyllodes tumors and is not necessarily a sign of extreme malignancy of these neoplasms.
Ladesich
James
J
Department of Surgical Pathology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA. jladesich@kumc.edu
Damjanov
Ivan
I
Persons
Diane
D
Jewell
William
W
Arthur
Teresa
T
Rogana
Jennifer
J
Davoren
Barbara
B
D001706:Biopsy; D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D003557:Phyllodes Tumor / Q000235:genetics* / Q000473:pathology