Dextrin as excipient in pharmaceutical preparations.
The addition of commercial dextrins to aqueous solvents in thin layer chromatography on cellulose increases the Rf values of azodyes such as methyl orange. The increase is less than with cyclodextrins but shows that dextrins also form supramolecular complexes. This should be considered when dextrins are used as "inert" excipients in pharmacy.
Lederer
M
M
Institut de Chimie Minérale et Analytique, BCH, Université de Lausanne, Switzerland.
Leipzig-Paganini
E
E
D001391:Azo Compounds / Q000737:chemistry; D002241:Carbohydrates / Q000737:chemistry; D002482:Cellulose / Q000737:chemistry; D002855:Chromatography, Thin Layer; D003912:Dextrins / Q000737:chemistry*; D005079:Excipients / Q000737:chemistry*; D007202:Indicators and Reagents; D012965:Sodium Chloride / Q000737:chemistry; D013213:Starch / Q000737:chemistry
D001391:Azo Compounds; D002241:Carbohydrates; D003912:Dextrins; D005079:Excipients; D007202:Indicators and Reagents; D012965:Sodium Chloride; C100258:methyl orange; D002482:Cellulose; D013213:Starch; C109691:microcrystalline cellulose