title: Identification of the cockroach neuropeptide Pea-CAH-II as a second adipokinetic hormone in the firebug Pyrrhocoris apterus.
abstract: A new member of the AKH/RPCH family was isolated from the corpora cardiaca of the firebug Pyrrhocoris apterus. It is the second adipokinetic peptide identified in this species. The peptide was characterized and its structure was deduced from the multiple MS(N) electrospray mass spectra as that of an octapeptide with the sequence pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-NH(2.) The peptide differs from the original P. apterus AKH (Pya-AKH) by one amino acid in position 3. Topical application and/or injection of the peptide induced lipid mobilization, but was inactive in mobilization of carbohydrates.
authors.affiliation: Institute of Entomology, Academy of Sciences, Branisovská 31, CZ-370 05, Ceské Budejovice, Czech Republic. kodrik@entu.cas.cz
authors.forename: Dalibor
authors.initials: D
authors.lastname: Kodrík
authors.forename: Petr
authors.initials: P
authors.lastname: Simek
authors.forename: Ludek
authors.initials: L
authors.lastname: Lepsa
authors.forename: Radomír
authors.initials: R
authors.lastname: Socha
mesh_terms: D000818:Animals; D003058:Cockroaches / Q000737:chemistry*; D020062:Heteroptera / Q000737:chemistry*; D007301:Insect Hormones / Q000302:isolation & purification*; D009479:Neuropeptides / Q000302:isolation & purification*; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives
chemical_list: D007301:Insect Hormones; C062950:Led-CC-II peptide; D009479:Neuropeptides; C451509:Pea-CAH-II neuropeptide; C069011:adipokinetic hormone, beetle; D011761:Pyrrolidonecarboxylic Acid