[Nosocomial catheter-related sepsis secondary to central venous catheters].
OBJECTIVE
To study bacteria and drug sensitivity of catheter-related sepsis (CRS).


METHODS
Between February 1993 and December 1997, 52 patients with central venous catheter-related sepsis were studied retrospectively.


RESULTS
The most common organisms were staphylococcus aureus and staphylococcus epidermis. The bacterial pathogens isolated demonstrated a marked pattern of antibiotic resistance. Gram-positive cocci were sensitive to vancomycin with a sensitivity of 93.3%, and gram-negative bacilli were sensitive to amikacin and ceftazidine with a sensitivity of 51.7%.


CONCLUSIONS
The effective treatment of catheter-related sepsis is removal of infected catheters. Vancomycin and (or) amikacin may be first chosen to treat CRS.
Wu
H
H
Department of Surgery, Zhongshan Hospital, Shanghai Medical University, Shanghai 200032.
Wu
Z
Z
Jin
D
D
Xu
J
J
D000583:Amikacin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D005260:Female; D006088:Gram-Negative Aerobic Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006095:Gram-Positive Cocci / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018805:Sepsis / Q000188:drug therapy / Q000209:etiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000302:isolation & purification; D014640:Vancomycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D014640:Vancomycin; D000583:Amikacin