Multivariate regression analysis on early mortality after orthotopic liver transplantation.
OBJECTIVE
To identify the risk factors relating to early mortality after orthotopic liver transplantation.


METHODS
Clinical data of 37 adult patients undergoing liver transplantation were retrospectively collected and divided into two groups: the survived group and the death group (survival time<30 d). The relationship between multivariate risk factors and early mortality after orthotopic liver transplantation were analyzed by stepwise logistic regression.


RESULTS
The survival rate was 73%. Early mortality rate was 27%. APACAE III, preoperative serum creatinine level and interoperative bleeding quantity had a significant independent association with early mortality. (R=0.1841, 0.2056 and 0.3738).


CONCLUSIONS
APACHE III,preoperative serum creatinine level and interoperative bleeding quantity are significant risk factors relating to early mortality after orthotopic liver transplantation. To improve the recipient's preoperative critical condition and renal function and to reduce interoperative bleeding quantity could lower the early mortality after orthotopic liver transplantation.
Qian
Ye-Ben
YB
Department of hepatic biliary surgery, first affiliated hospital An Hui Medical University, HeFei 230022, AnHui Province, China. ayqianyb@163.net
Cheng
Gui-Hua
GH
Huang
Jie-Fu
JF
D018806:APACHE; D000328:Adult; D016063:Blood Loss, Surgical / Q000401:mortality; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007668:Kidney / Q000502:physiology; D016031:Liver Transplantation / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate
D003404:Creatinine