title: Developmental biology: regulation by selective gene localization.
abstract: Recent studies have shown that, early during sporulation in Bacillus subtilis, the temporary exclusion of 70% of the chromosome from the forespore compartment is critical to the regulated activation of two major transcription factors, sigma(F) and sigma(E).
authors.affiliation: Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111-1800, USA. linc.sonenshein@tufts.edu
authors.forename: Abraham L
authors.initials: AL
authors.lastname: Sonenshein
mesh_terms: D001412:Bacillus subtilis / Q000166:cytology* / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001692:Biological Transport; D002455:Cell Division; D016764:Cell Polarity; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial / Q000235:genetics / Q000502:physiology*; D012808:Sigma Factor; D013171:Spores, Bacterial / Q000166:cytology / Q000235:genetics; D014157:Transcription Factors
chemical_list: D001426:Bacterial Proteins; D012808:Sigma Factor; D014157:Transcription Factors; C092468:spoIIR protein, Bacillus subtilis; C030069:spore-specific proteins, Bacillus