Clindamycin phosphate 1% gel in acne vulgaris.
A 12-week study compared Clindagel, a unique water-based gel formulation of clindamycin phosphate 1%, administered once daily, and Cleocin T, a slightly different gel formulation indicated for twice-daily use, in the treatment of acne vulgaris. Clindagel was safe and effective and equivalent to Cleocin T gel, albeit with a better tolerability profile. Clindagel is a viable alternative to Cleocin T gel.
Rizer
R L
RL
TJ Stephens & Associates, Colorado Springs, Colorado 80915, USA.
Sklar
J L
JL
Whiting
D
D
Bucko
A
A
Shavin
J
J
Jarratt
M
M
D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000891:Anti-Infective Agents, Local / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002981:Clindamycin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D003257:Consumer Product Safety; D004311:Double-Blind Method; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D005782:Gels; D002981:Clindamycin; C007084:clindamycin phosphate