Chemoselective heterocyclization and pharmacological activities of new heterocycles--a review. Part V-Synthesis of biocidal 4-thiazolidinones derivatives.
4-Thiazolidinones have been reported to possess biological activity especially fungicidal activity. With an intention to prepare some more 4-thiazolidinones as drugs for anti HIV and anticancer activity, we have synthesized some more 4-thiazolidinones by the action of mercaptoacetic acid on Schiff's base and/or heterocyclization of N-substituted thioureas with monochloracetic acid. Characterization of 4-thiazolidinone was deduced upon elemental and spectral analysis.
Abdel-Rahman
R M
RM
Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo, Egypt.
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology*
D000890:Anti-Infective Agents; D006571:Heterocyclic Compounds; D013844:Thiazoles