title: Acute pancreatitis secondary to isotretinoin-induced hyperlipidemia.
abstract: Isotretinoin is a vitamin-A derivative most commonly utilized in the treatment of severe recalcitrant nodulocystic acne. Derangement of lipid metabolism leading to increased triglyceride and cholesterol level has been reported after taking this drug. We report the case of a 43-year-old female with no identifiable risk factor for pancreatitis who developed acute pancreatitis associated with hyperlipidemia while being treated with isotretinoin for hidradenitis suppurativa. To our knowledge, this is the third reported case of isotretinoin-induced hyperlipidemia leading to acute pancreatitis.
authors.affiliation: St. Anthony Hospital, 608 NW 9th Street, Suite 4100, Oklahoma City, OK 73102, USA.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Jamshidi
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Obermeyer
authors.forename: Satish
authors.initials: S
authors.lastname: Govindaraj
authors.forename: Armand
authors.initials: A
authors.lastname: Garcia
authors.forename: Abdul
authors.initials: A
authors.lastname: Ghani
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D017497:Hidradenitis Suppurativa / Q000188:drug therapy; D006801:Humans; D006949:Hyperlipidemias / Q000139:chemically induced* / Q000150:complications*; D015474:Isotretinoin / Q000009:adverse effects* / Q000627:therapeutic use; D010195:Pancreatitis / Q000209:etiology*
chemical_list: D015474:Isotretinoin