title: [The percentage of free prostate specific antigen used in detecting prostate cancer].
abstract: OBJECTIVE
  To evaluate the value of the percentage of free prostate specific antigen in detecting prostate cancer.
  
  
  METHODS
  Serum free prostate specific antigen (F-PSA) and total PSA were measured with immunoradiometric assay, and the free/total PSA ratio was calculated. In 117 patients, 31 had prostate carcinoma and 86 BPH.
  
  
  RESULTS
  The free/total PSA ratio was lower in patients with prostate cancer than in those with BPH. If the total serum PSA level was limited with in 4 - 10 ng/ml, the free/total PSA ratio can be used in the differential diagnosis of prostate cancer and BPH except total PSA.
  
  
  CONCLUSIONS
  The free/total PSA ratio can be used in the differential diagnosis of prostate cancer and BPH, especially when serum PSA level is limited with in 4 - 10 ng/ml.
authors.affiliation: Department of Urology, Huashan Hospital, Shanghai Medical University, Shanghai 200040.
authors.forename: L
authors.initials: L
authors.lastname: Yang
authors.forename: Z
authors.initials: Z
authors.lastname: Fang
authors.forename: J
authors.initials: J
authors.lastname: Song
authors.forename: S
authors.initials: S
authors.lastname: Deng
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D006801:Humans; D015592:Immunoradiometric Assay; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D017430:Prostate-Specific Antigen / Q000097:blood*; D011470:Prostatic Hyperplasia / Q000175:diagnosis*; D011471:Prostatic Neoplasms / Q000175:diagnosis*
chemical_list: D017430:Prostate-Specific Antigen