Trichosporon asahii: an unusual cause of invasive infection in neonates.
Trichosporon asahii causes white piedra, an infection of hair shafts and onychomycosis in immunocompetent patients, as well as various localized or disseminated invasive infections in immunodeficient hosts. We describe a 26-week gestation 890-g vaginally delivered female neonate who had severe respiratory distress syndrome and on the sixth day of life developed Klebsiella pneumoniae sepsis. At the same time two blood cultures were positive for T. asahii. The neonate was also colonized with T. asahii in the pharynx and perineum. The infant was successfully treated with conventional amphotericin B.
Panagopoulou
Paraskevi
P
Third Department of Pediatrics, Aristotle University of Thessaloniki, Greece.
Evdoridou
Joanna
J
Bibashi
Evangelia
E
Filioti
Joanna
J
Sofianou
Danai
D
Kremenopoulos
George
G
Roilides
Emmanuel
E
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D007710:Klebsiella Infections / Q000150:complications; D007711:Klebsiella pneumoniae / Q000302:isolation & purification / Q000472:pathogenicity; D009181:Mycoses / Q000188:drug therapy / Q000473:pathology*; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology; D018805:Sepsis; D014250:Trichosporon / Q000302:isolation & purification* / Q000472:pathogenicity*
D000935:Antifungal Agents; D000666:Amphotericin B