title: [Tooth development in children with cleft lip and palate. An international inquiry into unilateral cleft lip, jaw and palate].
abstract: In a cross-sectional study of 106 European children with unilateral complete cleft lip, alveolus and palate ranging from 10 to 15 years of age, dental maturity was determined using orthopantomograms. The method and standards (the 50th percentile line) of Demirjian were used. The study shows a significant delay of dental maturity in both male and female cleft-affected patients. This delay in tooth development supports Van Limborgh's theory that the origin of clefts is due to the delayed growth and development of parts of the dentofacial area.
authors.affiliation: Afdeling Orthodontie, Academisch Centrum Tandheelkunde Amsterdam (ACTA).
authors.forename: J P
authors.initials: JP
authors.lastname: Souren
authors.forename: B
authors.initials: B
authors.lastname: Prahl-Andersen
mesh_terms: D000293:Adolescent; D002648:Child; D002971:Cleft Lip / Q000503:physiopathology*; D002972:Cleft Palate / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008445:Maxillofacial Development; D014070:Tooth / Q000254:growth & development*