title: A novel phosphate chemosensor utilizing anion-induced fluorescence change.
abstract: [structure: see text] The neutral receptor N,N'-bis[3,5-di[(1-pyrenylmethyl)carbamoyl]benzyl] pyridine-2,6-dicarbamide (2) provides a pseudo-tetrahedron cleft and multiple hydrogen bondings to form a 1:1 complex with phosphate ion in a highly selective manner, by comparison with other anions (F(-), Cl(-), Br(-), SCN(-), AcO(-), NO(3)(-), ClO(4)(-), and HSO(4)(-)). The binding strength can be inferred from the emission intensity ratio of the pyrene monomer (lambda(max) 377 nm) to the excimer (lambda(max) 477 nm). Fluorescence titration, X-ray analysis, and NMR studies support a proposed complexation model.
authors.affiliation: Department of Chemistry, National Taiwan University, Taipei, Taiwan 106, Republic of China.
authors.forename: Jen-Hai
authors.initials: JH
authors.lastname: Liao
authors.forename: Chao-Tsen
authors.initials: CT
authors.lastname: Chen
authors.forename: Jim-Min
authors.initials: JM
authors.lastname: Fang
mesh_terms: D018360:Crystallography, X-Ray; D005453:Fluorescence; D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010710:Phosphates / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D007202:Indicators and Reagents; C451484:N,N'-bis(3,5-di-((1-pyrenylmethyl)carbamoyl)benzyl)pyridine-2,6-dicarbamide; D010710:Phosphates; D011721:Pyrenes; D011725:Pyridines