Spontaneous clinical regression in chronic lymphocytic leukaemia.
Chronic lymphocytic leukaemia (CLL) is a B-cell disorder, which has a median survival of over 10 years from diagnosis for stage A disease. The natural history of stage A disease is generally indolent or only slowly progressive. It is less well known that CLL may undergo spontaneous regression. We report a series of 10 such cases (eight stage A and two stage B) followed at our institutions.
Thomas
Ranjit
R
Department of Haematology, Western General Hospital, Edinburgh, UK.
Ribeiro
Isabel
I
Shepherd
Patricia
P
Johnson
Peter
P
Cook
Margaret
M
Lakhani
Anil
A
Kaczmarski
Richard
R
Carrington
Patrick
P
Catovsky
Daniel
D
D000368:Aged; D002881:Chromosomes, Human, Pair 12; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D014314:Trisomy