title: [Precancerous conditions and neoplasms of the anal area].
abstract: Classification of this lesions could be done concerning localisation and histological type. Squamous cell carcinoma of the anal canal are the most often to be found, but overall neoplasias in this region are very seldom. The most important role in pathogenesis seems to play infection with HPV viruses. Symptoms are in the beginning unspecific and similar to other common proctological diseases. Proctological diagnostic procedures are to be combined with cytological methods. Therapeutic management depends on malignant potential of the lesions and contains local excision, total operation and combined radiochemotherapy, which is today considered standard therapy of squamous cell carcinoma of the anal canal.
authors.affiliation: Proktologisches Institut München-Ost, Chirurgische Privatklinik Bogenhausen, Denninger Strasse 44, 81679 München.
authors.forename: D
authors.initials: D
authors.lastname: Geile
authors.forename: G
authors.initials: G
authors.lastname: Osterholzer
authors.forename: J
authors.initials: J
authors.lastname: Müller
mesh_terms: D001003:Anal Canal / Q000473:pathology / Q000601:surgery; D001005:Anus Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D009367:Neoplasm Staging; D011230:Precancerous Conditions / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D018714:Radiotherapy, Adjuvant