The first glycosides isolated from propolis: diterpene rhamnosides.
Two diterpene glycosides, ent-8(17)-labden-15-O-alpha-L-rhamnoside and ent-8(17)-labden-15-O-(3'-O-acetyl)-alpha-L-rhamnoside (new natural compounds) were isolated from propolis from El Salvador. The compounds showed significant antibacterial activity and moderate toxicity to Artemia salina nauplii. These are the first glycosides reported in bee glue.
Popova
M
M
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia.
Bankova
V
V
Tsvetkova
I
I
Naydenski
C
C
Silva
M V
MV
D000818:Animals; D001156:Artemia / Q000187:drug effects; D033364:Decapoda / Q000187:drug effects; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D008958:Models, Molecular; D010063:Ovum / Q000187:drug effects; D011429:Propolis / Q000737:chemistry*; D012210:Rhamnose / Q000737:chemistry* / Q000302:isolation & purification
D004224:Diterpenes; D006027:Glycosides; D011429:Propolis; D012210:Rhamnose