[Colon cancer risk factors in Jiashan county, Zhejiang province, the highest incidence area in China].
OBJECTIVE
To investigate the risk factors of colon cancer in the highest incidence area, Jiashan county, providing scientific basis for monitoring and prevention.


METHODS
With a population-based case-control study, 109 colon cancer patients with 1:7 matched controls were interviewed with uniform questionnaires. Conditional logistic regression was used for univariate and multivariate analysis of colon cancer.


RESULTS
Ten years before, high monthly pork consumption (OR = 1.608), high monthly animal oil consumption (OR = 1.391), psychological depression (OR = 9.887), negative emotion (OR = 1.723), lower digestive tract diseases (OR = 4.163), and history of colorectal cancer in the first degree relatives (OR = 3.421) were the main risk factors of colon cancer. At that time, high monthly vegetable consumption was a protective factor for colon cancer (OR = 0.422).


CONCLUSIONS
Colon cancer in Jiashan county was related to dietary factors. The research results support the colon cancer etiological hypothesis of "fat-bile acid" and "deficiency of dietary fibres". Psychological depression, inheritance and lower digestive tract diseases were also correlated with colon cancer.
Wang
X
X
Zhejiang Cancer Institute, Hangzhou 310022, China.
Lei
T
T
Ma
X
X
D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D003110:Colonic Neoplasms / Q000453:epidemiology* / Q000378:metabolism / Q000523:psychology; D005260:Female; D005502:Food; D006801:Humans; D015994:Incidence; D008297:Male; D015999:Multivariate Analysis; D012307:Risk Factors; D011795:Surveys and Questionnaires