[Morphologic analysis of 14 cases of hepatic angiomyolipoma].
OBJECTIVE
To study the morphology of hepatic angiomyolipoma (HAML).


METHODS
HE staining, PAS staining, immunohistochemistry and electronic microscopy were used to study 10 cases from our department and 4 cases from consultation.


RESULTS
All 14 HAML cases showed perivascular epithelioid cells (PEC) with 4 different types of morphology. They presented characteristic PAS positivity premelanosome like structures and dense body under electronic microscopy. Immunohistochemistry demonstrated positive reaction for both actin and HMB45.


CONCLUSIONS
Light and electronmicroscopic features and immunophenotype of HAML are characteristic of PEC related lesion.
Zhong
D
D
Department of Pathology, Chinese PLA General Hospital, Beijing 100853, China.
Ji
X
X
Li
X
X
D000199:Actins / Q000378:metabolism; D000328:Adult; D018207:Angiomyolipoma / Q000378:metabolism / Q000473:pathology*; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged
D000199:Actins