The incidence of non ulcer dyspepsia and its response to treatment.
BACKGROUND
This study was undertaken to identify Non Ulcer Dyspepsia (NUD) in young patients presenting with peptic ulcer like symptoms. Their response to treatment was also determined.


METHODS
100 patients between the ages of 20-40 of both sexes were included in the study. Investigations done were Chest X-ray Plain Abdominal X-ray, ECG, ESR, LFTs Amylase Abdominal Ultrasound and upper GI endoscopy. All patients then received 6-week therapy with Omeprazole and Helicobacter Pylori eradication with Clarithromycin and Tinidazole.


RESULTS
NUD was by far the most common cause (59%) in both the sexes. Response to therapy was unsatisfactory.


CONCLUSIONS
This relatively newly discovered clinical entity should be kept in mind while dealing with patients presenting with refractory dyspeptic symptoms.
Khan
J
J
Department of Medicine, Ayub Medical College, Abbottabad.
Javed
M
M
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D004415:Dyspepsia / Q000188:drug therapy / Q000453:epidemiology; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy; D016480:Helicobacter pylori / Q000187:drug effects; D006801:Humans; D015994:Incidence; D008297:Male; D009853:Omeprazole / Q000627:therapeutic use; D014011:Tinidazole / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D014011:Tinidazole; D017291:Clarithromycin; D009853:Omeprazole