[Functional activity of endotoxin binding factors in chronic viral hepatitis B and C].
The functional state of cell-mediated and humoral antiendotoxin factors in patients with chronic viral hepatitides B and C has been studied. A decreased content of antibodies to glycolipid of chemotype Re and to Escherichia coli O14 with common enterobacterial antigen was shown to occur in these diseases. In addition, a decreased number of neutrophils, eosinophils and thrombocytes has been noted. The conclusion has been made that patients with chronic hepatitides are not protected from the pathogenic action of endotoxin penetrating from the intestines into the systemic blood stream.
Sozinov
A S
AS
State Medical University, Research Institute of Epidemiology and Microbiology, Kazan, Russia.
Anikhovskaia
I A
IA
Enaleeva
D Sh
DSh
Zinkevich
O D
OD
Likhoded
V G
VG
Salakhov
I M
IM
Tkacheva
S V
SV
Iakovlev
M Iu
MIu
D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000276:immunology; D001792:Blood Platelets / Q000276:immunology; D004731:Endotoxins / Q000276:immunology; D004755:Enterobacteriaceae / Q000276:immunology; D004804:Eosinophils / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology; D006017:Glycolipids / Q000276:immunology; D019694:Hepatitis B, Chronic / Q000097:blood / Q000276:immunology*; D019698:Hepatitis C, Chronic / Q000097:blood / Q000276:immunology*; D006801:Humans; D007958:Leukocyte Count; D009504:Neutrophils / Q000276:immunology; D010976:Platelet Count
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D004731:Endotoxins; D006017:Glycolipids; C055264:Re-glycolipid; C044101:endotoxin, Escherichia coli