title: Electrogenerated base-induced N-acylation of chiral oxazolidin-2-ones. Part 2.
abstract: An improved and efficient electrochemical N-acylation of chiral oxazolidin-2-ones has been achieved. The generation of the nitrogen anion is obtained under mild conditions and without addition of base or probase, by direct electrolysis of a solution of MeCN-TEAP containing the oxazolidinone. Acylation agents (acid chlorides or anhydrides) were added at the end of the electrolysis. N-Acylated products were isolated in high to excellent yields.
authors.affiliation: Dipartimento Ingegneria Chimica, Materiali, Materie Prime e Metallurgia, Università La Sapienza, via Castro Laurenziano, 7, I-00161 Roma, Italy. marta.feroci@uniroma1.it
authors.forename: Marta
authors.initials: M
authors.lastname: Feroci
authors.forename: Achille
authors.initials: A
authors.lastname: Inesi
authors.forename: Laura
authors.initials: L
authors.lastname: Palombi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Sotgiu