[Cycloferon in treating duodenal ulcers in rats].
The possibility of using cycloferon (interferon inductor) for a complex treatment (in combination with the main drug solcoseryl possessing pronounced therapeutic properties) of duodenum ulcers was experimentally studied in male rats. The experiments showed a considerable difference in the interferon status of animals with model duodenum ulcers treated with cycloferon, solcoseryl, their combination, and placebo (control). The healing effect of solcoseryl administered in combination with cycloferon exceeded that of each component administered separately.
Bul'on
V V
VV
Department of Neuropharmacology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, ul. Akademika Pavlova 12, St. Petersburg, 197376 Russia.
Khnychenko
L K
LK
Sapronov
N S
NS
Kuznetsova
N N
NN
Anikin
V B
VB
arinenko
R Iu
RIu
Kovalenko
A L
AL
Alekseeva
L E
LE
D000166:Acridines / Q000008:administration & dosage / Q000627:therapeutic use*; D000183:Actihaemyl / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy*; D007369:Interferon Inducers / Q000008:administration & dosage / Q000627:therapeutic use*; D015227:Lipid Peroxidation; D008297:Male; D010919:Placebos; D051381:Rats
D000166:Acridines; D007369:Interferon Inducers; D010919:Placebos; D000183:Actihaemyl; C026430:10-carboxymethyl-9-acridanone