Tuberous sclerosis.
Tuberous sclerosis (TS) is an autosomal dominant disorder with a significant range of clinical expression. Renal, pulmonary, central nervous system, and cardiac complications may result in severe morbidity. Early recognition of the syndrome is important to ensure prompt identification of systemic involvement. We review the clinical features of tuberous sclerosis and discuss recent advances in our understanding of its pathogenesis and appropriate management.
Harris-Stith
Ronea
R
Department of Internal Medicine, Wilford Hall Medical Center, Lackland Air Force Base, San Antonio, Texas, USA.
Elston
Dirk M
DM
D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D005148:Facial Dermatoses / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012720:Severity of Illness Index; D017678:Sex Distribution; D014402:Tuberous Sclerosis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*