[Selective intraarterial infusion chemotherapy using a combined MRI-angiography system for head and neck cancers].
We performed selective intraarterial infusion chemotherapy using a combined MRI-angiography system for head and neck cancers. In three patients, three or five infusions of CDDP (100 mg/body) were administered to the feeding arteries selectively. For the evaluation of drug distribution, MRI during arteriography through the infusion pump was performed before CDDP administration. When a distribution mismatch was found, arterial selection was attempted again under a mechanically unstable C-arm system, and further evaluation under an MR system was carried out. Thus, more ideal treatment could be provided. We consider MRI during arteriography to be useful in assessing for distribution during intraarterial chemotherapy.
Mori
Harushi
H
Department of Radiology, Graduate School of Medicine, University of Tokyo.
Hayashi
Naoto
N
Aoki
Shigeki
S
Masumoto
Tomohiko
T
Yoshikawa
Takeharu
T
Abe
Osamu
O
Ohtomo
Kuni
K
Yuge
Tadashi
T
Kaga
Kimitaka
K
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002945:Cisplatin / Q000008:administration & dosage*; D006258:Head and Neck Neoplasms / Q000188:drug therapy*; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged
D000970:Antineoplastic Agents; D002945:Cisplatin