[Lung sarcoidosis following instillation of mitomycin C in the urinary bladder].
Intravesical prophylaxis against recurrence of urinary bladder carcinomas using mitomycin C (MMC) has proved to be and effective treatment with few side effects. Previously only two cases of lung toxicity after instillation of MMC into the urinary bladder has been described. We report a 65-year-old man in whom lung sarcoidosis occurred after intravesical administration of MMC. This association has not been reported to date. The clinical picture and the pathogenesis of this lung disease are discussed.
Cuervo Pinna
M A
MA
Servicio de Medicina Interna, Hospital Regional Universitario Infanta Cristina, Badajoz. cuervo@grn.es
Cuervo Pinna
C
C
Macías Castillo
S
S
Bureo Dacal
J C
JC
Espada Alonso
M J
MJ
Pimentel Leo
J
J
D000283:Administration, Intravesical; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage / Q000009:adverse effects*; D017565:Sarcoidosis, Pulmonary / Q000139:chemically induced* / Q000175:diagnosis; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy
D000903:Antibiotics, Antineoplastic; D016685:Mitomycin