title: [Penetrating keratoplasty in active herpes simplex stromal keratitis].
abstract: OBJECTIVE
  To evaluate the efficacy of penetrating keratoplasty (PKP) in treating active herpes simplex stromal keratitis.
  
  
  METHODS
  PKP was performed on 59 patients with quiescent and 66 patients with active herpes simplex stromal keratitis. The results and complications of herpes simplex keratitis (HSK) in the quiescent group were compared with that of the HSK active group.
  
  
  RESULTS
  No clinical or statistical significant differences in visual outcome, graft transparent rate and recurrent rate of HSK after operation were identified between the active and quiescent groups.
  
  
  CONCLUSIONS
  When the pre- and intra-operative managements of PKP are properly performed on active HSK, the same results as that performed on quiescent HSK can be obtained, and it can reduce the complications and shorten the duration of the disease.
authors.affiliation: Shandong Eye Institute & Hospital, Shandong Acdemy of Medical Sciences, Qingdao 266071, China.
authors.forename: X
authors.initials: X
authors.lastname: Dong
authors.forename: W
authors.initials: W
authors.lastname: Shi
authors.forename: L
authors.initials: L
authors.lastname: Xie
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use; D003319:Corneal Stroma / Q000187:drug effects / Q000601:surgery* / Q000821:virology; D005260:Female; D006801:Humans; D016849:Keratitis, Herpetic / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D015948:Keratoplasty, Penetrating / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir