Three tetrahydroisoquinolinedione derivatives.
N-(2-Chlorobenzyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione, C(16)H(12)ClNO(2), crystallizes in P2(1)/n with three crystallographically independent molecules in the asymmetric unit, which differ slightly in conformation, N-(2-bromo-4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione, C(16)H(12)BrNO(2), crystallizes in P2(1)/n with one molecule in the asymmetric unit and N-(2,3-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione, C(15)H(9)Cl(2)NO(2), crystallizes in P2(1)/c with one molecule in the asymmetric unit. In all three structures, the heterocyclic rings adopt approximately planar conformations. The pyridine rings are orthogonal to the substituted phenyl rings. In all three structures, the crystal packing is stabilized by intermolecular C-H...O hydrogen bonds.
Subbiah Pandi
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Department of Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai 600 025, India.
Rajakannan
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Velmurugan
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Parvez
Masood
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Kim
Moon Jib
MJ
Senthilvelan
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Narasinga Rao
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S
D006860:Hydrogen Bonding; D007546:Isoquinolines / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D044005:Tetrahydroisoquinolines
D007546:Isoquinolines; C455524:N-(2-bromo-4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione; C455523:N-(2-chlorobenzyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione; C455525:N-(2-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione; D044005:Tetrahydroisoquinolines