[Menadione and roboxin as inducers of immunomodulating activity of erythrocyte stroma].
The erythrocyte stroma of intact rats treated with riboxin can be used, after an additional extracorporal treatment with menadione, as a transaphthogenic softly acting immunostimulant. Introduced into rats with a secondary experimental immunodeficient syndrome caused by indomethacin or gentamycin, this stroma leads to normalization of the humoral immune response to ram erythrocytes.
Uteshev
B S
BS
Pharmacology Department, State Medical University, ul. Ostrovityanova 1, Moscow, 117437 Russia.
Konollia
N A
NA
Prokopenko
L G
LG
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects* / Q000276:immunology; D007290:Inosine Diphosphate / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D017154:Stromal Cells / Q000187:drug effects* / Q000276:immunology; D024483:Vitamin K 3 / Q000494:pharmacology*
D000276:Adjuvants, Immunologic; D024483:Vitamin K 3; D007290:Inosine Diphosphate