title: Selenium levels in biological matrices in adult population of Mumbai, India.
abstract: Selenium (Se) levels in whole blood, serum, urine, muscle and saliva of Mumbai adults have been estimated by differential pulse cathodic stripping voltammetry (DPCSV); the detection limit of Se is 0.05 ng ml(-1). The reliability of estimation is further assessed through the analysis of Standard Reference Materials. The Se levels in whole blood (n = 35) and blood serum (n = 201) of the Mumbai adult population is 99.6 and 100 ng ml(-1); approximately 34.8% of the population have serum Se levels between 80 and 100 ng ml(-1). The blood serum levels of Se for Mumbai adults are comparable to those of whole blood. The mean concentration of Se in urine on a 24-h basis is 5.2 ng ml(-1). Muscle and saliva of the Mumbai adult population contain 195.4 ng g(-1) and 2 ng ml(-1) of Se, respectively. A good correlation between serum Se and dietary Se is observed with a correlation coefficient of 0.89.
authors.affiliation: Environmental Assessment Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
authors.forename: R
authors.initials: R
authors.lastname: Raghunath
authors.forename: R M
authors.initials: RM
authors.lastname: Tripathi
authors.forename: S
authors.initials: S
authors.lastname: Mahapatra
authors.forename: S
authors.initials: S
authors.lastname: Sadasivan
mesh_terms: D000328:Adult; D004032:Diet; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D018482:Muscle, Skeletal / Q000737:chemistry; D012016:Reference Values; D012463:Saliva / Q000737:chemistry; D012643:Selenium / Q000032:analysis / Q000493:pharmacokinetics*; D014018:Tissue Distribution
chemical_list: D012643:Selenium