title: Apoptosis: letting slip the dogs of war.
abstract: Recent studies have shown that, during cell death, the protein Omi is released from the mitochondrial intermembrane space into the cytosol, where it augments caspase-dependent apoptosis by blocking inhibitors and may induce caspase-independent cell death via its serine protease activity.
authors.affiliation: Department of Cellular Immunology, La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA.
authors.forename: Beni B
authors.initials: BB
authors.lastname: Wolf
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Green
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D020169:Caspases / Q000378:metabolism; D004789:Enzyme Activation; D000074923:High-Temperature Requirement A Serine Peptidase 2; D051034:Inhibitor of Apoptosis Proteins; D019476:Insect Proteins / Q000235:genetics / Q000378:metabolism; D024101:Mitochondrial Proteins; D008954:Models, Biological; D011506:Proteins; D017386:Sequence Homology, Amino Acid; D012697:Serine Endopeptidases / Q000235:genetics / Q000378:metabolism
chemical_list: D051034:Inhibitor of Apoptosis Proteins; D019476:Insect Proteins; D024101:Mitochondrial Proteins; D011506:Proteins; D012697:Serine Endopeptidases; D000074923:High-Temperature Requirement A Serine Peptidase 2; D020169:Caspases