title: [A study on the prevention of selenite cataract with taurine].
abstract: OBJECTIVE
  To evaluate the prevention of selenite cataract with taurine.
  
  
  METHODS
  A prior injection of taurine was given intraperitoneally to Wistar rats 2 days before the selenite challenge and a following daily injection of taurine was needed until the experiment was finished. All of the rats were examined under a split-lamp microscope on selected days.
  
  
  RESULTS
  0.5% taurine showed no effect on lenses, 1%, 2% and 4% taurine could delay the development of nuclear opacity, and 2% and 4% taurine could also delay the development of cortical opacity.
  
  
  CONCLUSIONS
  Taurine can prevent the development of selenite cataract. Its effect is dose-dependent.
authors.affiliation: Beijing Institute of Ophthalmology, Beijing 100730.
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Chen
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002386:Cataract / Q000517:prevention & control*; D004305:Dose-Response Relationship, Drug; D051381:Rats; D017208:Rats, Wistar; D018038:Sodium Selenite / Q000633:toxicity*; D013654:Taurine / Q000627:therapeutic use*
chemical_list: D013654:Taurine; D018038:Sodium Selenite