Crystallization and synchrotron X-ray diffraction studies of human interleukin-22.
Human interleukin-22, a novel member of the cytokine family, has been crystallized in hanging drops using the vapour-diffusion technique. Preliminary X-ray diffraction experiments using synchrotron radiation reveal that the protein crystallizes in space group P2(1)2(1)2(1), with unit-cell parameters a = 55.44, b = 61.62, c = 73.43 A, and diffracts beyond 2.00 A resolution.
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Laboratório Nacional de Luz Síncrotron, Caixa Postal 6192, CEP 13083-970, Campinas, SP, Brazil.
Lucchesi
K W
KW
Colau
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Dumoutier
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Renauld
J-C
JC
Polikarpov
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I
D003460:Crystallization; D018360:Crystallography, X-Ray; D006801:Humans; D007378:Interleukins / Q000737:chemistry*; D011487:Protein Conformation; D011994:Recombinant Proteins / Q000737:chemistry; D000097043:Interleukin-22
D007378:Interleukins; D011994:Recombinant Proteins; D000097043:Interleukin-22