Preconception seroconversion and maternal seronegativity at delivery do not rule out the risk of congenital toxoplasmosis.
We describe two unusual cases of congenital toxoplasmosis, one occurring after preconception maternal infection with cervical adenopathies and the other occurring after maternal infection at the very end of pregnancy with maternal seronegativity at delivery. These documented cases of congenital toxoplasmosis demonstrate the value of extending the serologic monitoring period during pregnancy, according to the individual clinical context.
Chemla
C
C
Division of Parasitology, Reims Toxoplasmosis Group, Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire, EA2070, IFR 53, Reims 51092, France.
Villena
I
I
Aubert
D
D
Hornoy
P
P
Dupouy
D
D
Leroux
B
B
Bory
J P
JP
Pinon
J M
JM
D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood*; D036861:Delivery, Obstetric; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000469:parasitology; D007223:Infant; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D012307:Risk Factors; D014125:Toxoplasmosis, Congenital / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology*
D000913:Antibodies, Protozoan