title: Post-RT CT results as a predictive model for the necessity of planned post-RT neck dissection in patients with cervical metastatic disease from squamous cell carcinoma.
abstract: OBJECTIVE
  To establish whether the extent of neck disease on postradiation therapy (RT) computed tomography (CT) can predict the likelihood of positive neck nodes and, thereby, the necessity of planned post-RT neck dissection.
  
  
  METHODS
  Ninety-five patients who underwent post-RT neck dissection within 2 months for squamous cell carcinoma of the head and neck were eligible. Of the 95 patients, 37 (32.7%) of 113 hemineck specimens were pathologically positive. On post-RT CT imaging studies, the number and size of lymph nodes >1 cm were recorded. Internal focal defects and the likelihood of extracapsular spread were graded.
  
  
  RESULTS
  If lymph nodes on post-RT CT were < or = 15 mm, free of significant internal focal low-attenuation or calcification, and without imaging evidence of extracapsular spread, the surgical hemineck specimen was positive in 1 (3.4%) of the 29 hemineck specimens. A focal low-attenuation defect (p = 0.0078) and evidence of extracapsular spread (p = 0.0721) seen in the residual nodal mass on CT were independent predictors of a positive surgical specimen by multivariate analysis.
  
  
  CONCLUSIONS
  CT findings on post-RT neck studies can help predict the likelihood of residual disease and, thereby, the necessity of planned post-RT neck dissection.
authors.affiliation: Department of Radiology, University of Florida College of Medicine, Gainesville, FL 32610, USA.
authors.forename: Hiroya
authors.initials: H
authors.lastname: Ojiri
authors.forename: William M
authors.initials: WM
authors.lastname: Mendenhall
authors.forename: Scott P
authors.initials: SP
authors.lastname: Stringer
authors.forename: Patches L
authors.initials: PL
authors.lastname: Johnson
authors.forename: Anthony A
authors.initials: AA
authors.lastname: Mancuso
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed