[Structural and functional features of the ovaries as a risk factor for ovarian cancer in infertile women].
In examining 502 female patients with cancer of the ovaries (OC) infertility was identified in 21.9 percent of cases. The prevalent form of infertility was tubal infertility (92.7%), there were but a few instances of the endocrine form (1.8%). The infertile women were studied for their hormonal and receptorial status (receptors of estradiol and progesterone). It has been established that women with the endocrine variant of infertility present with more prominent hormonal inadequacies in the hypophysis-ovaries system and manifest changes in the receptorial status of the ovaries than those with tubal infertility; the findings in the latter have not been shown to be different from controls. In endocrine infertility OC is in fact not encountered, which fact can be related to morphological features of the ovaries giving origin to endocrine disturbances, and to a decline in the receptorial status and absence of ovulation.
Iakimova
T P
TP
Dudnichenko
A S
AS
Kartashov
S M
SM
D000328:Adult; D004958:Estradiol / Q000097:blood / Q000172:deficiency; D005187:Fallopian Tubes / Q000473:pathology; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000209:etiology* / Q000473:pathology; D010053:Ovary / Q000378:metabolism / Q000473:pathology*; D010060:Ovulation / Q000378:metabolism; D010902:Pituitary Gland / Q000378:metabolism; D011374:Progesterone / Q000097:blood / Q000172:deficiency; D011959:Receptors, Estradiol / Q000378:metabolism; D011980:Receptors, Progesterone / Q000378:metabolism; D012307:Risk Factors
D011959:Receptors, Estradiol; D011980:Receptors, Progesterone; D011374:Progesterone; D004958:Estradiol