title: Botulinum toxin A: successful décolleté rejuvenation.
abstract: BACKGROUND
  Décolleté wrinkles develop with age. In women more than 35 years of age these wrinkles are still transient, but become permanent at about age 50. In a substantial number of women décolleté wrinkles, seem to be associated with an insertion of platysma exceeding the second intercostal space. We report botulinum A toxin therapy of these wrinkles in five patients.
  
  
  OBJECTIVE
  To show the effect of botulinum A toxin on décolleté wrinkles.
  
  
  METHODS
  All five women with décolleté lines treated with botulinum A had different varieties of the platysma muscle inserting deep down beneath the fourth intercostal space. During platysma contraction injection points were marked and a certain dosage of toxin was applied.
  
  
  RESULTS
  Two weeks after therapy a significant improvement of the treated décolleté region was observed.
  
  
  CONCLUSIONS
  These observations indicated that botulinum A toxin can be an effective and safe method in the temporary management of décolleté wrinkles. It should therefore be considered as a new adjuvant treatment in cosmetic décolleté rejuvenation.
authors.affiliation: Department of Dermatology, Heinrich-Heine-University, Düsseldorf, Germany.
authors.forename: Petra Maria
authors.initials: PM
authors.lastname: Becker-Wegerich
authors.forename: Lucie
authors.initials: L
authors.lastname: Rauch
authors.forename: Thomas
authors.initials: T
authors.lastname: Ruzicka
mesh_terms: D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D015595:Skin Aging / Q000187:drug effects / Q000473:pathology; D013909:Thorax; D016896:Treatment Outcome
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A