title: [Study on the application of random amplified polymorphic DNA in Yersinia pestis genotyping].
abstract: OBJECTIVE
  To study the type of 103 Y. pestis strains that isolated from different plague foci and different ecological types.
  
  
  METHODS
  Random amplified polymorphic DNA (RAPD) was used.
  
  
  RESULTS
  Y. pestis were divided into two RAPD types: most strains that isolated from elsewhere in the country belonged to RAPD-1 type, while most strains that isolated from Qinghai province were RAPD-2 type.
  
  
  CONCLUSIONS
  The genome structures of different ecotype Y. pestis were different providing the foundation of further research and prevention of plague.
authors.affiliation: Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing 102206, China.
authors.forename: F
authors.initials: F
authors.lastname: Huang
authors.forename: D
authors.initials: D
authors.lastname: Yu
authors.forename: R
authors.initials: R
authors.lastname: Hai
authors.forename: H
authors.initials: H
authors.lastname: Cai
mesh_terms: D000818:Animals; D002681:China; D005838:Genotype; D006801:Humans; D019105:Random Amplified Polymorphic DNA Technique / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D015010:Yersinia pestis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification