[Effect of electrical stimulation of the trigeminal nucleus caudatus on the blood microvessel permeability in the eye in normal and capsaicin-treated rats].
Electrical stimulation of the trigeminal caudate nucleus increased permeability of the eye blood microvessels in rats. Ten days after capsaicin pre-treatment (total dose 150 mg/kg, s/c for 2 days: 20, 30, 50, 50 mg/kg) the electrical stimulation did not evoke any changes of the microvascular permeability in the eye. The data suggest that the effect of the stimulation is mediated through capsaicin-sensitive neurones of the trigeminal ganglion.
Tolochko
Z S
ZS
Institute of Physiology, Russian Acad. Med. Sci., 4 Timakov st., Novosibirsk 630117, Russia.
D000818:Animals; D002199:Capillary Permeability; D002211:Capsaicin / Q000494:pharmacology*; D004558:Electric Stimulation; D005123:Eye / Q000098:blood supply*; D008297:Male; D008833:Microcirculation; D009474:Neurons / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D014275:Trigeminal Caudal Nucleus / Q000502:physiology*; D012668:Trigeminal Ganglion / Q000502:physiology*
D002211:Capsaicin