title: [Primary orthostatic tremor].
abstract: BACKGROUND
  Tremor is frequent in neurologic practice but primary orthostatic tremor was first described in 1984. Its prevalence accounts for around 4% for tremors explored in neurophysiology; in contrast, essential and parkinsonian tremors represent respectively 28 and 22% of these cases.
  
  
  METHODS
  Orthostatic tremor is characterized by its appearance while standing. Walking, sitting, and lying down are unaffected. Clinical examination is normal except for unsteadiness disappearing when walking. Surface electromyography in the standing position is necessary for the diagnosis and shows a regular rapid tremor (frequency around 14 to 18 Hz). Its pathophysiology is unknown.
  
  
  CONCLUSIONS
  Clonazepam is the first-line treatment for orthostatic tremor. In cases of resistance or side effects of this drug orthostatic tremor may be improved by primidone or, as in our case, gabapentin.
authors.affiliation: Service de médecine interne 4, hôpital Louis-Mourier, 178, rue des Renouillers, 92700 Colombes, France. secretariat.medecine4@lmr.ap-hop-paris.fr
authors.forename: A
authors.initials: A
authors.lastname: Pradalier
authors.forename: E
authors.initials: E
authors.lastname: Apartis
authors.forename: D
authors.initials: D
authors.lastname: Vincent
authors.forename: C
authors.initials: C
authors.lastname: Campinos
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D011187:Posture; D014202:Tremor / Q000209:etiology*