title: Clinical study of acute low-tone sensorineural hearing loss: survey and analysis of glycerol test and orthostatic test.
abstract: Fifty patients (14 men and 36 women ranging in age from 16 to 66 years) with acute low-tone sensorineural hearing loss (ALHL) were retrospectively analyzed in this study. The glycerol test and the orthostatic test were performed. On the glycerol test, 43.8% of 16 ears of the 14 men and 33.3% of 39 ears of the 36 women with ALHL had a positive result. On the orthostatic test, 42.9% of the 14 men and 52.7% of the 36 women with ALHL had a positive result. In addition, 28.6% of the 14 men and 33.3% of the 36 women had hypotension with a systolic blood pressure of 100 mm Hg or less. Our results suggest that endolymphatic hydrops as shown by the glycerol test and an underlying autonomic imbalance and/or insufficient blood circulation as shown by the orthostatic test may be important factors in the causation of ALHL.
authors.affiliation: Department of Otolaryngology, Yamanashi Medical University, Japan.
authors.forename: Izuru
authors.initials: I
authors.lastname: Nozawa
authors.forename: Shun-ichi
authors.initials: S
authors.lastname: Imamura
authors.forename: Akihito
authors.initials: A
authors.lastname: Mizukoshi
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Honda
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Okamoto
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D018159:Endolymphatic Hydrops / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005990:Glycerol / Q000008:administration & dosage; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000150:complications* / Q000175:diagnosis; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D005990:Glycerol