Recurrent hypersensitivity to Combivir.
The non-nucleoside reverse transcriptase inhibitors (NNRTIs) are commonly used in combination antiretroviral therapy and are associated with hypersensitivity reactions on induction therapy. We report a case of recurrent hypersensitivity associated with Combivir, when there was a delay in determining the cause as the NNRTIs were considered to be the more likely cause.
Winston
Alan
A
Department of GU/HIV Medicine, Chelsea & Westminster Hospital, London SW10 9NH, UK.
McLean
Ken
K
D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects*; D004338:Drug Combinations; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D015497:HIV-1 / Q000187:drug effects; D006801:Humans; D019259:Lamivudine / Q000009:adverse effects*; D012008:Recurrence; D015215:Zidovudine / Q000009:adverse effects*
D019380:Anti-HIV Agents; D004338:Drug Combinations; C109078:lamivudine, zidovudine drug combination; D019259:Lamivudine; D015215:Zidovudine