[Effects of tripterygium wilfordii polyglyco - sidium on intraocular inflammatory reaction after intraocular lens implantation].
OBJECTIVE
The effects of tripterygium wilfordii polyglyco - sidium (TWP) on intraocular inflammatory reaction after extracapsular cataract extraction and intraocular lens (IOL) implantation were studied.


METHODS
120 cases with senile cataract were divided into two groups: (1) Patients received TWP after IOL implantation; (2) patients received prednisone after IOL implantation. The slit - lamp was used to observe inflammatory cells and fibrinous exudate in the aqueous humor and cellular deposits on IOL on the 1st, 3rd, 7th and 14th postoperative days.


RESULTS
The study indicated that on the 1st, 3rd, 7th and 14th postoperative days the inflammatory cells and fibrinous exudate in the aqueous humor and cellular deposits on IOL were significantly lower in TWP - treated group than that in steroid - treated group (P < 0.05).


CONCLUSIONS
TWP is effective in reducing postoperative anterior ocular inflammation after extracapsular cataract extraction and IOL implantation. The TWP is more effective than the steroid in suppressing postoperative intraocular inflammatory reaction.
Zhou
Z
Z
Department of Ophthalmology, No. 304 Hospital, Beijing 100037.
He
S
S
Liang
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D009877:Endophthalmitis / Q000188:drug therapy*; D005260:Female; D006027:Glycosides / Q000627:therapeutic use*; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011183:Postoperative Complications / Q000188:drug therapy*; D029757:Tripterygium
D006027:Glycosides