[A study on the risk factors of congenital urogenital malformations].
OBJECTIVE
To explore risk factors for congenital urogenital malformations.


METHODS
A hospital-based category matching case-control study was performed to investigate the characteristics of 95 cases with congenital urogenital malformations and 160 controls. Parents were interviewed for their characteristics before and during conception. Unconditional logistic regression analysis was used for single factor and multivariate analysis to estimate odds ratios and their 95% confidence intervals.


RESULTS
There were 71 male infants in the overall congenital urogenital malformations (Ratio = 74.4%, Chi(2) = 74.863, P = 0.001) identified. Statistically significant associations were calculated for the pregnant women suffering from cold during first and/or second trimester (OR = 7.034, 95% CI = 3.488 - 14.187), for a low birthweight delivery (OR = 4.075, 95% CI = 1.774 - 9.362), for maternal times of pregnancy >/= 2 (OR = 3.133, 95% CI = 1.514 - 6.483) and exposure to occupational detrimental chemicals before pregnancy (OR = 10.496, 95% CI = 1.053 - 104.651).


CONCLUSIONS
The risk factors of congenital urogenital malformations were suffering from cold during first and/or second trimester, male infants, low birthweight delivery, times of pregnancy >/= 2 and exposure to occupational detrimental chemicals before pregnancy.
Wang
J
J
Department of Epidemiology, Public Health College of Haerbin Medical University, Haerbin 150001, China.
Wang
B
B
Zhao
J
J
D001724:Birth Weight; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010298:Parity; D012307:Risk Factors; D012733:Sex Differentiation; D014564:Urogenital Abnormalities / Q000209:etiology*