A note on the quantitative properties of McGhee-von Hippel model.
Exact closed-form expressions are presented for the properties of the McGhee-von Hippel model of non-specific binding of large ligands to one-dimensional homogeneous lattices. These properties include the midpoint location and the slope at the middle point of the binding isotherms (v varies with ln L plots), the location and magnitude of the maximum, as well as the location of the inflection point, in the Scatchard plots (v/L varies with v plots).
Kong
Yong
Y
CuraGen Corporation, 555 Long Wharf Drive, New Haven, CT 06511, USA. ykong@curagen.com
D000465:Algorithms; D007700:Kinetics; D008024:Ligands; D008962:Models, Theoretical; D013816:Thermodynamics
D008024:Ligands