Alpha-smooth-muscle actin in and contraction of porcine dental pulp cells.
The finding of expression of a muscle actin isoform, alpha-smooth-muscle actin (SMA), by the stromal cells of several tissues prompted this study of SMA expression by cells derived from the porcine dental pulp. The SMA content of the cells increased with time in culture. These SMA-containing cells were found to have the capability to contract a collagen-glycosaminoglycan analog of extracellular matrix in vitro.
Brock
D P
DP
Harvard School of Dental Medicine, Boston, MA, USA.
Marty-Roix
R
R
Spector
M
M
D000199:Actins / Q000032:analysis* / Q000235:genetics / Q000502:physiology; D000704:Analysis of Variance; D000818:Animals; D000911:Antibodies, Monoclonal; D015153:Blotting, Western; D002452:Cell Count; D002478:Cells, Cultured; D002809:Chondroitin Sulfates / Q000737:chemistry / Q000378:metabolism; D024042:Collagen Type I / Q000737:chemistry / Q000378:metabolism; D004247:DNA / Q000032:analysis; D003782:Dental Pulp / Q000166:cytology / Q000378:metabolism*; D005109:Extracellular Matrix / Q000378:metabolism*; D005612:Freeze Drying; D005786:Gene Expression Regulation; D007150:Immunohistochemistry; D016062:Porosity; D020033:Protein Isoforms / Q000032:analysis / Q000235:genetics / Q000502:physiology; D013223:Statistics as Topic; D017154:Stromal Cells / Q000378:metabolism; D013499:Surface Properties; D013552:Swine
D000199:Actins; D000911:Antibodies, Monoclonal; D024042:Collagen Type I; D020033:Protein Isoforms; D002809:Chondroitin Sulfates; D004247:DNA