title: Dental disease indices and caries related oral microflora in children with phenylketonuria.
abstract: The purpose of this study was to investigate the dental caries, plaque and gingivitis indices and caries related oral flora in children with classic phenylketonuria. Forty-one children at The Great Ormond Street Hospital for Children and controls were included in the study. The main findings were: No significant difference in the decayed, missing and filled surfaces of the primary and permanent teeth between the phenylketonuria children and the controls. A significantly greater mean plaque score for the control children compared with the phenylketonuria children (p < 0.01) for the permanent teeth only. A significantly greater number of white opacities in the permanent teeth of the phenylketonuria group compared with the control group (p < 0.02). No significant differences in the caries related microflora.
authors.affiliation: Department of Oral Medicine, Eastman Dental Institute for Oral Health Care Sciences, University of London, 256 Gray's Inn Road, London WC1X 8LD.
authors.forename: V S
authors.initials: VS
authors.lastname: Lucas
authors.forename: A
authors.initials: A
authors.lastname: Contreras
authors.forename: M
authors.initials: M
authors.lastname: Loukissa
authors.forename: G J
authors.initials: GJ
authors.lastname: Roberts
mesh_terms: D002176:Candida albicans / Q000254:growth & development; D002327:Cariostatic Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000150:complications / Q000382:microbiology*; D003743:Dental Enamel / Q000002:abnormalities; D003773:Dental Plaque / Q000150:complications / Q000382:microbiology; D003774:Dental Plaque Index; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D005891:Gingivitis / Q000150:complications; D006801:Humans; D007778:Lactobacillus / Q000254:growth & development; D008297:Male; D010512:Periodontal Index; D010661:Phenylketonurias / Q000150:complications*; D012463:Saliva / Q000382:microbiology; D013223:Statistics as Topic; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000254:growth & development*; D014076:Tooth Diseases / Q000150:complications*; D014094:Tooth, Deciduous / Q000473:pathology
chemical_list: D002327:Cariostatic Agents; D005459:Fluorides