Optically active cyclic hexapeptides with covalently attached pyrene probes: selective alkaline earth metal ion recognition using excimer emission.
[structure: see text] The synthesis of two optically active pyrene-modified cyclic hexapetides and their selectivity toward the complexation of alkaline earth metal ions are reported. Complexation was studied by optical and chiroptical methods. The cyclic peptides are forming 2:1 sandwich complexes with the metal ions.
Strauss
Jörg
J
Institut für Organische Chemie, Universität Regensburg, Universitätsstrasse 31, D-93053 Regensburg.
Daub
Jörg
J
D002118:Calcium / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry; D008673:Metals, Alkaline Earth / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D015335:Molecular Probes / Q000737:chemistry; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism; D009904:Optical Rotation; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000378:metabolism; D011721:Pyrenes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D017186:Titrimetry
D005456:Fluorescent Dyes; D008673:Metals, Alkaline Earth; D015335:Molecular Probes; D009842:Oligopeptides; D010456:Peptides, Cyclic; D011721:Pyrenes; D002118:Calcium