New methodologies for the oxidation of Fischer carbene complexes: synthesis of hydrazides.
[reaction: see text] We report new, high-yield methodologies for oxidizing Fischer carbenes, particularly hydrazinocarbene complexes. The reagents traditionally used to oxidize Fischer carbenes have failed because of the stability of hydrazinocarbene complexes and the easy oxidation of formed hydrazides in the reaction conditions. The three newly developed methodologies are very mild, fast, efficient, and complementary. Differently functionalized hydrazinocarbene complexes can be oxidized to afford new hydrazides.
Perdicchia
Dario
D
Dipartimento di Chimica Organica e Industriale, Università degli Studi di Milano, Via C. Golgi, 19, I-20133 Milan, Italy. dario.perdicchia@unimi.it
Licandro
Emanuela
E
Maiorana
Stefano
S
Vandoni
Barbara
B
Baldoli
Clara
C