Direct absorption of acylated anthocyanin in purple-fleshed sweet potato into rats.
Absorption of acylated anthocyanins in purple-fleshed sweet potato (Ipomoea batatas cv. Ayamurasaki) in rats was studied to obtain evidence that the acylated anthocyanins themselves could exert a physiological function in vivo. Peonidin 3-caffeoylsophoroside-5-glucoside (Pn 3-Caf*sop-5-glc) in purple-fleshed sweet potato was directly absorbed into rat and present as an intact acylated form in plasma. After oral administration of the purple-fleshed sweet potato anthocyanin (PSA) concentrate containing 38.9 micromol of Pn 3-Caf*sop-5-glc/kg of body weight, Pn 3-Caf*sop-5-glc was detected in the plasma, and the C(max) value and t(max) were estimated as 50.0 +/- 6.8 nmol/Lof plasma and 30 min, respectively. Furthermore, the plasma antioxidant capacity was significantly elevated from 58.0 +/- 12.0 to 89.2 +/- 6.8 micromol of Trolox equivalent/L of plasma 30 min after the administration of the PSA concentrate.
Suda
Ikuo
I
National Agricultural Research Center for Kyushu Okinawa Region, National Agricultural Research Organization, Nishigoshi, Kikuchi, Kumamoto 861-1192, Japan. ikuosu@affrc.go.jp
Oki
Tomoyuki
T
Masuda
Mami
M
Nishiba
Yoichi
Y
Furuta
Shu
S
Matsugano
Kazusato
K
Sugita
Koichi
K
Terahara
Norihiko
N
D000042:Absorption; D000215:Acylation; D000818:Animals; D000872:Anthocyanins / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D000975:Antioxidants / Q000032:analysis; D001578:Benzopyrans / Q000097:blood / Q000493:pharmacokinetics; D002851:Chromatography, High Pressure Liquid; D027723:Ipomoea batatas / Q000737:chemistry*; D007700:Kinetics; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D000872:Anthocyanins; D000975:Antioxidants; D001578:Benzopyrans; C103379:peonidin 3-O-(6-O-caffeyl-2-O-glucopyranosyl-beta-glucopyranosyl)-5-O-glucoside