title: Examples of the role of analytical chemistry in environmental risk management research.
abstract: Analytical chemistry is an important tier of environmental protection and has been traditionally linked to compliance and/or exposure monitoring activities for environmental contaminants. The adoption of the risk management paradigm has led to special challenges for analytical chemistry applied to environmental risk analysis. Namely, methods developed for regulated contaminants may not be appropriate and/or applicable to risk management scenarios. This paper contains examples of analytical chemistry applied to risk management challenges broken down by the analytical approach and analyte for some selected work in our laboratory. Specific techniques discussed include stable association complex electrospray mass spectrometry (cESI-MS), gas chromatography-mass spectrometry (GC-MS), split-flow thin cell (SPLITT) fractionation and matrix-assisted laser desorption time of flight mass spectrometry (MALDI-ToF-MS). Specific analytes include haloacetic acids (HAA9), perchlorate, bromate, triazine degradation products, metal-contaminated colloids and Cryptosporidium parvum oocysts.
authors.affiliation: US Environmental Protection Agency, Office of Research and Development, National Risk Management Research Laboratory, Cincinnati, OH 45268, USA. magnuson.matthew@epa.gov
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Magnuson
authors.forename: Catherine A
authors.initials: CA
authors.lastname: Kelty
authors.forename: Edward T
authors.initials: ET
authors.lastname: Urbansky
authors.forename: James H
authors.initials: JH
authors.lastname: Owens
authors.forename: Keith C
authors.initials: KC
authors.lastname: Kelty
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Speth
mesh_terms: D000085:Acetates / Q000032:analysis; D000818:Animals; D003102:Colloids; D016785:Cryptosporidium parvum / Q000302:isolation & purification; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006540:Herbicides / Q000032:analysis; D013058:Mass Spectrometry / Q000379:methods; D010472:Perchlorates / Q000032:analysis; D018570:Risk Assessment; D017670:Sodium Compounds / Q000032:analysis; D014227:Triazines; D014873:Water Pollutants / Q000032:analysis*
chemical_list: D000085:Acetates; D003102:Colloids; D006540:Herbicides; D010472:Perchlorates; D017670:Sodium Compounds; D014227:Triazines; D014873:Water Pollutants; C031068:sodium perchlorate