title: [Effect of laser exposure on hemostatic parameters in the preagonal and post-resuscitation period].
abstract: Effects of intravascular low-intensive laser exposure of the blood on the hemostasis during acute blood loss and the early postresuscitation period after 4-min clinical death were studied on narcotized dogs (8-17 kg) of both sexes with different initial levels of heparin. During the preagonal period laser exposure caused hypercoagulation in animals with initial heparin content below 60 micrograms/ml. This acceleration of blood clotting prevented a drop in the activity of antithrombin III and hypercoagulation by the third hour of postresuscitation period. In animals with initial heparin content more than 60 micrograms/ml laser exposure caused hypocoagulation in the presence of reduced activity of antithrombin III by the third hour of the resuscitation period.
authors.forename: N E
authors.initials: NE
authors.lastname: Iakovleva
authors.forename: L A
authors.initials: LA
authors.lastname: Liapina
authors.forename: I S
authors.initials: IS
authors.lastname: Novoderzhkina
authors.forename: A K
authors.initials: AK
authors.lastname: Kirsanova
authors.forename: V L
authors.initials: VL
authors.lastname: Kozhura
mesh_terms: D000818:Animals; D000990:Antithrombin III / Q000378:metabolism; D004285:Dogs; D005260:Female; D006487:Hemostasis / Q000528:radiation effects*; D007834:Lasers; D008297:Male; D012151:Resuscitation
chemical_list: D000990:Antithrombin III