MHC class I genes of the tree shrew Tupaia belangeri.
Two MHC class I cDNA sequences from the tree shrew (Tupaia belangeri), Tube-W01 and Tube-W02, have been isolated which are probably derived from classical class I genes. Expression of the tupaia class I genes was investigated in several organs, in particular the brain, in which slightly different amounts of class I transcripts are detectable in different areas. Gene tree analysis performed with Tube-W01 and Tube-W02, and including class I sequences derived from other orders, indicated that the tupaia sequences cluster differently from Primates, Carnivora, Artiodactyla, Perissodactyla, and Rodentia, but might be related to Lagomorpha class I genes.
Flügge
Perris
P
Abteilung Immungenetik, Universität Göttingen, Heinrich-Düker-Weg 12, 37073 Göttingen, Germany.
Fuchs
Eberhard
E
Günther
Eberhard
E
Walter
Lutz
L
D000595:Amino Acid Sequence; D000818:Animals; D020869:Gene Expression Profiling; D005805:Genes, MHC Class I / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D012333:RNA, Messenger / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D014418:Tupaiidae / Q000235:genetics* / Q000276:immunology
D012333:RNA, Messenger