title: In vivo evidence for brain-to-blood efflux transport of valproic acid across the blood-brain barrier.
authors.affiliation: Graduate School of Pharmaceutical Sciences, University of Tokyo, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
authors.forename: Atsuyuki
authors.initials: A
authors.lastname: Kakee
authors.forename: Hitomi
authors.initials: H
authors.lastname: Takanaga
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Hosoya
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Sugiyama
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Terasaki
mesh_terms: D000818:Animals; D001812:Blood-Brain Barrier / Q000187:drug effects / Q000502:physiology*; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000502:physiology; D018682:GABA Agents / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D015233:Models, Statistical; D021381:Protein Transport; D051381:Rats; D017207:Rats, Sprague-Dawley; D014635:Valproic Acid / Q000494:pharmacology*
chemical_list: D018682:GABA Agents; D014635:Valproic Acid