title: [48XXYY Klinefelter's syndrome with recurrent foot ulcers: a case report].
abstract: A case of 48XXYY Klinefelter's syndrome diagnosed with foot ulcers, in a 43-year-old man, is reported. He presented to the Department of Dermatology in our hospital with the chief complaint of recurrent foot ulcers. He was referred to us because of atrophic external genitalia. The present condition and endocrinological examination suggested Klinefelter's syndrome. Chromosomal analysis revealed that his chromosomal type is 48XXYY. This is the 24th case of Klinefelter's syndrome with 48XXYY chromosome and is the 5th case associated with foot ulcers in Japan. Here we report this case together with a brief review of the previously reported cases.
authors.affiliation: Department of Urology, Osaka Koseinenkin Hospital.
authors.forename: Yasuteru
authors.initials: Y
authors.lastname: Noda
authors.forename: Daizo
authors.initials: D
authors.lastname: Oka
authors.forename: Norihide
authors.initials: N
authors.lastname: Tei
authors.forename: Shingo
authors.initials: S
authors.lastname: Takada
authors.forename: Takuo
authors.initials: T
authors.lastname: Koide
authors.forename: Susumu
authors.initials: S
authors.lastname: Miyajima
authors.forename: Natsuko
authors.initials: N
authors.lastname: Okada
mesh_terms: D016523:Foot Ulcer / Q000209:etiology*; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000150:complications* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D012008:Recurrence