Analyses of the evolutionary distribution of Salmonella translocated effectors.
The type III secretion system encoded by Salmonella pathogenicity island 2 (SPI2) translocates Salmonella translocated effectors (STE) into host cells. STE are encoded by genes outside of SPI2. The distribution of STE loci within the salmonellae was investigated. In contrast to the SPI2 locus that is conserved within Salmonella enterica, STE loci show a variable distribution. In addition to other virulence determinants, the possession of various sets of STE loci may contribute to the different host ranges and pathogenic potentials of S. enterica serovars.
Hansen-Wester
Imke
I
Institut für Klinische Mikrobiologie, Immunologie und Hygiene, FAU Erlangen-Nürnberg, Erlangen, Germany.
Stecher
Bärbel
B
Hensel
Michael
M
D001426:Bacterial Proteins; D005075:Biological Evolution; D022761:Gene Transfer, Horizontal; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006023:Glycoproteins / Q000235:genetics; D019779:Salmonella enterica / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity*; D012703:Serotyping
D001426:Bacterial Proteins; D006023:Glycoproteins; C421862:SifA protein, Salmonella