title: Triterpenes from Mimusops elengi.
abstract: Pentacyclic triterpenes (1) and (2) have been isolated from Mimusops elengi and assigned structures 3beta,6beta,19alpha,23-tetrahydroxy-urs-12-ene and 1beta-hydroxy-3beta-hexanoyllup-20 (29)-ene-23, 28-dioic acid, respectively, on the basis of spectroscopic studies including 2D-NMR. The compound 1 showed moderate inhibiting activity against beta-glucuronidase enzyme
authors.affiliation: International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Pakistan.
authors.forename: N
authors.initials: N
authors.lastname: Jahan
authors.forename: A
authors.initials: A
authors.lastname: Malik
authors.forename: G
authors.initials: G
authors.lastname: Mustafa
authors.forename: Z
authors.initials: Z
authors.lastname: Ahmad
authors.forename: S
authors.initials: S
authors.lastname: Ahmad
authors.forename: E
authors.initials: E
authors.lastname: Anis
authors.forename: S
authors.initials: S
authors.lastname: Malik
authors.forename: S
authors.initials: S
authors.lastname: Shujaat
authors.forename: N
authors.initials: N
authors.lastname: Afza
authors.lastname: Atta-Ur-Rahman
mesh_terms: D000818:Animals; D002417:Cattle; D002855:Chromatography, Thin Layer; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005966:Glucuronidase / Q000037:antagonists & inhibitors*; D020128:Inhibitory Concentration 50; D008099:Liver; D013058:Mass Spectrometry; D008519:Medicine, Traditional; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010154:Pakistan; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C447719:1beta-hydroxy-3beta-hexanoyllup-20 (29)-ene-23, 28-dioic acid; C447702:3beta,6beta,19alpha,23-tetrahydroxy-urs-12-ene; D004791:Enzyme Inhibitors; D014315:Triterpenes; D005966:Glucuronidase