title: Motor dominant neuropathy in Sjögren's syndrome: report of two cases.
abstract: Most of the peripheral neuropathies in Sjögren's syndrome (SS) are sensory- or autonomic-dominant. In this report, we present two cases of a rare type of neuropathy, motor dominant neuropathy, in SS. One showed signs similar to those of Guillain-Barré syndrome, and the other showed signs characteristic of chronic inflammatory demyelinating polyradiculoneuropathy. These patients received i.v. immunoglobulin therapy. To our knowledge, this is the first report indicating that i.v. immunoglobulin has beneficial effects on motor dominant neuropathy in SS.
authors.affiliation: Third Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Mochizuki
authors.forename: Keiko
authors.initials: K
authors.lastname: Kamakura
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Masaki
authors.forename: Akira
authors.initials: A
authors.lastname: Hirata
authors.forename: Ryohji
authors.initials: R
authors.lastname: Nakamura
authors.forename: Kazuo
authors.initials: K
authors.lastname: Motoyoshi
mesh_terms: D000368:Aged; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D020275:Guillain-Barre Syndrome / Q000175:diagnosis; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D018908:Muscle Weakness / Q000209:etiology; D009188:Myelitis, Transverse / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D009431:Neural Conduction; D011115:Polyneuropathies / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis; D011239:Prednisolone / Q000627:therapeutic use; D011782:Quadriplegia / Q000209:etiology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis; D013116:Spinal Cord / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology
chemical_list: D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D011239:Prednisolone; D008775:Methylprednisolone