[Acute experimental pancreatitis in the opossum. The role of prior truncular vagotomy on the inflammatory response].
BACKGROUND
Acute pancreatitis (AP) is a common cause of admission to the emergency room. Its etiopathogeny is poorly understood. The pancreatic inflammatory response in this process is unclear. The influence of the autonomic nervous system is a controversial issue.


OBJECTIVE
To demonstrate the effects of truncular vagotomy on AP due to duodenal distention in the South American opossum. PLACE OF APPLICATION: Department of experimental surgery (Churruca-Visca Hospital) INEUCI (Neuroscience Institute, CONICET, UBA).


METHODS
Male and female South American opossum divided into: a control group (7 animals); group A: truncular vagotomy and pyloroplasty seven days after the onset of AP (7 animals). Group B: truncular vagotomy and pyloroplasty 30 days after provoking AP (7 animals). Group C: truncular vagotomy and pyloroplasty 45 days after the onset of AP (7 animals).


METHODS
Acute pancreatitis was caused by duodenal distention of the second portion by inserting a Foley catheter through a gastrostomy.


CONCLUSIONS
The method of provoking AP is original. The influence of autonomous nervous system is being underestimated in most of the literature available.
García
H A
HA
Sección Cirugía Experimental, Servicio de Cirugía General, Complejo Hospitalario Churruca-Visca.
Tiscornia
O M
OM
Iodice
O
O
Cal
P
P
Gasali
F J
FJ
Maschietto
A
A
Sapin
F
F
Eufemio
G
G
Sutera
S
S
Uchiumi
L
L
Affani
J
J
D000208:Acute Disease; D000818:Animals; D004386:Duodenum / Q000503:physiopathology; D005260:Female; D008297:Male; D009893:Opossums; D010195:Pancreatitis / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D011446:Prospective Studies; D011708:Pylorus / Q000601:surgery; D013997:Time Factors; D015167:Vagotomy, Truncal / Q000379:methods*