Optic nerve involvement in neuro-Behcet's disease.
BACKGROUND
To report the ocular manifestations of neuro-Behcet's disease.


METHODS
A 34-year-old woman had recurrent meningitis. She developed diplopia, headache, and ataxia, and was diagnosed as having neuro-Behcet's disease.


METHODS
Imaging revealed two infarct foci in the transitional midbrain and pons. After treatment with prednisolone and colchicine, the diplopia resolved. Two years later, a scotoma developed in the right eye, in which the best-corrected visual acuity was 4/200. Papillitis and a prepapillary vitreous opacity were seen in the right fundus. These findings disappeared 11 days after subconjunctival steroid injections and increased colchicine. Her vision gradually improved to 20/20 two months later.


CONCLUSIONS
Neuro-Behcet's disease may manifest with transient optic neuritis and prepapillary vitreous opacity.
Nakamura
Toru
T
Department of Ophthalmology, Gunma University School of Medicine, Maebashi, Japan.
Takahashi
Kyoichi
K
Kishi
Shoji
S
D000328:Adult; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D003078:Colchicine / Q000627:therapeutic use; D004172:Diplopia / Q000175:diagnosis; D004359:Drug Therapy, Combination; D005128:Eye Diseases / Q000175:diagnosis; D005260:Female; D006261:Headache / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D009900:Optic Nerve / Q000473:pathology*; D009902:Optic Neuritis / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D014822:Vitreous Body / Q000473:pathology
D011239:Prednisolone; D003078:Colchicine