title: Topographic analysis of corneal regularity after penetrating keratoplasty.
abstract: OBJECTIVE
  To evaluate the accuracy of the Holladay Diagnostic Summary of the EyeSys Corneal Analysis System in predicting the corneal visual acuity potential in patients who have undergone penetrating keratoplasty (PKP).
  
  
  METHODS
  Astigmatism patterns, refractive and topographic astigmatism, best spectacle-corrected visual acuity (BSCVA), and hard contact lens (HCL) visual acuity of 54 patients were analyzed 3 months after PKP and compared with the Potential Corneal Acuity (PCA) value predicted by the Holladay Diagnostic Summary.
  
  
  RESULTS
  Qualitative patterns of astigmatism (p = 0.01) and refractive (p = 0.002) and topographic (p = 0.0002) astigmatism were significantly correlated with PCA values. Using HCL visual acuities to correct the BSCVA (HCL-corrected BSCVA) for noncorneal causes of reduced vision, we found that the PCA values of 48.1% of the patients were within one line of the HCL-corrected BSCVA; 81.5% were within two lines; and 93.0% were within three lines.
  
  
  CONCLUSIONS
  The Holladay PCA measurement may be useful in the postoperative evaluation of the optical quality of the central corneal surface in patients who have undergone PKP.
authors.affiliation: Department of Ophthalmology, New England Eye Center and Tufts University School of Medicine, Boston, Massachusetts, U.S.A.
authors.forename: Pierre E
authors.initials: PE
authors.lastname: Demers
authors.forename: Roger F
authors.initials: RF
authors.lastname: Steinert
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Gould
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001251:Astigmatism / Q000175:diagnosis*; D003315:Cornea / Q000473:pathology*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000473:pathology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012029:Refraction, Ocular; D015203:Reproducibility of Results; D014792:Visual Acuity