title: The inflammatory polyp-fold complex in children.
abstract: The inflammatory polyp-fold complex (IPFC) is an uncommon endoscopic or radiologic finding in children. In this complex, an inflammatory polyp at the gastroesophageal junction is present, often in continuity with a prominent gastric fold. Histologically, there is an inflammatory infiltrate in otherwise benign gastric and esophageal mucosa. We report four cases of IPFC in children, all associated with reflux esophagitis. In two patients who underwent repeat endoscopy, acid suppression therapy led to a decrease in the size of the polyp and histologic improvement of esophagitis. Four case studies in children with IPFC are presented, followed by a literature review of this endoscopic finding as it applies to children.
authors.affiliation: Division of Pediatric Gastroenterology and Nutrition, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA. pbishop@ped.umsmed.edu
authors.forename: Phyllis R
authors.initials: PR
authors.lastname: Bishop
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Nowicki
authors.forename: Charu
authors.initials: C
authors.lastname: Subramony
authors.forename: Paul H
authors.initials: PH
authors.lastname: Parker
mesh_terms: D000293:Adolescent; D002648:Child; D016145:Endoscopy, Digestive System; D004935:Esophageal Diseases / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D004942:Esophagitis, Peptic / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D007249:Inflammation / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D008297:Male; D011127:Polyps / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D013272:Stomach Diseases / Q000150:complications* / Q000473:pathology* / Q000628:therapy