title: Synthesis of cyclic dienamide using ruthenium-catalyzed ring-closing metathesis of ene-ynamide.
abstract: [reaction: see text] Ring-closing metathesis of ene-ynamide using the second-generation Grubbs' catalyst produced nitrogen-containing heterocycles, which have dienamide moieties, in high yields. Diels-Alder reaction of the cyclized product and dienophile proceeded smoothly to afford a bi- or tricyclic compound.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
authors.forename: Nozomi
authors.initials: N
authors.lastname: Saito
authors.forename: Yukako
authors.initials: Y
authors.lastname: Sato
authors.forename: Miwako
authors.initials: M
authors.lastname: Mori
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D001685:Biological Factors / Q000138:chemical synthesis; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry
chemical_list: D000475:Alkenes; D000480:Alkynes; D000577:Amides; D001685:Biological Factors; D006571:Heterocyclic Compounds; D012428:Ruthenium