Analyses of the roles of the three cheA homologs in chemotaxis of Vibrio cholerae.
The Vibrio cholerae genome revealed the presence of multiple sets of chemotaxis genes, including three cheA gene homologs. We found that the cheA-2, but not cheA-1 or cheA-3, gene is essential for chemotaxis under standard conditions. Loss of chemotaxis had no effect on virulence factor expression in vitro.
Gosink
Khoosheh K
KK
Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
Kobayashi
Reiji
R
Kawagishi
Ikuro
I
Häse
Claudia C
CC
D001426:Bacterial Proteins; D002633:Chemotaxis; D017353:Gene Deletion; D005798:Genes, Bacterial; D005816:Genetic Complementation Test; D015151:Immunoblotting; D008565:Membrane Proteins / Q000032:analysis / Q000235:genetics / Q000378:metabolism*; D000072236:Methyl-Accepting Chemotaxis Proteins; D014734:Vibrio cholerae / Q000378:metabolism* / Q000472:pathogenicity; D014774:Virulence
D001426:Bacterial Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins