Role of nitric oxide in ovulation, meiotic maturation of oocytes, and implantation in mice.
Nitric oxide synthase blockers inhibited meiotic maturation of oocytes, decreased the count of oocytes during hormonal stimulation of superovulation, and increased embryonic death in experimental females mated with intact males.
Blashkiv
T V
TV
Department of Immunology and Cytosera, A. A. Bogomolets Institute of Physiology, Ukrainian Academy of Sciences, Kiev. imm@serv.biph.iev.ua
Korniichuk
A N
AN
Voznesenskaya
T Y
TY
Pornichenko
A G
AG
D000818:Animals; D010064:Embryo Implantation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005260:Female; D006062:Gonadotropins / Q000494:pharmacology; D051379:Mice; D008808:Mice, Inbred CBA; D019331:NG-Nitroarginine Methyl Ester / Q000494:pharmacology; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase; D009865:Oocytes / Q000378:metabolism*; D010053:Ovary / Q000502:physiology; D010060:Ovulation / Q000378:metabolism*; D013997:Time Factors
D004791:Enzyme Inhibitors; D006062:Gonadotropins; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D019331:NG-Nitroarginine Methyl Ester