T memory cells: quality not quantity.
Immunological memory to pathogens is associated with clonal expansion and heightened responsiveness of antigen-specific T cells. Recent work emphasizes that, for efficient protective immunity, qualitative changes in T memory cells are vitally important.
Sprent
Jonathan
J
Department of Immunology, IMM4, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA. jsprent@scripps.edu
D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D007156:Immunologic Memory; D019041:L-Selectin / Q000378:metabolism; D008089:Listeria monocytogenes / Q000276:immunology; D008088:Listeriosis / Q000276:immunology; D051379:Mice; D018448:Models, Immunological; D013601:T-Lymphocytes / Q000276:immunology*
D019041:L-Selectin