title: Feline hyperthyroidism: advances towards novel molecular therapeutics.
abstract: Feline hyperthyroidism is the most common endocrine disorder of the elderly cat. Traditionally, the disease is treated by surgical thyroidectomy, medical management with antithyroid drugs or radiation therapy using iodine-131. However, none of these treatments is ideal and molecular therapeutics may offer novel methods of treating the disease. This article reviews the background of, and preliminary investigations into, the development of a transcriptionally targeted somatic gene therapy strategy for the treatment of this feline condition.
authors.affiliation: Molecular Therapeutics Research Group, Division of Small Animal Clinical Studies, Faculty of Veterinary Medicine, University of Glasgow.
authors.forename: L
authors.initials: L
authors.lastname: Blackwood
authors.forename: D J
authors.initials: DJ
authors.lastname: Argyle
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000628:therapy*; D002415:Cats; D015316:Genetic Therapy / Q000662:veterinary*; D006980:Hyperthyroidism / Q000188:drug therapy / Q000662:veterinary*; D014162:Transfection / Q000662:veterinary*