title: Endodontic treatment of teeth associated with a large periapical lesion.
abstract: OBJECTIVE
  To report the healing of a large periapical lesion following non-surgical root canal treatment.
  
  
  CONCLUSIONS
  A 12-year-old male with a large periapical lesion around the apices of his mandibular incisors is described. The lesion formed after trauma to the mandibular anterior teeth 5 years previously. During root canal treatment, chlorhexidine gluconate was used for irrigation, and calcium hydroxide was used both for the intracanal dressing and as a base of the root canal sealer. Periapical healing was observed 3 months after obturation and continued at the 12-month review. Key learning points Root canal treatment, including the use of chlorhexidine gluconate and calcium hydroxide for infection control, led to substantial healing of a large periapical lesion. This report confirms that large periapical lesions can respond favourably to non-surgical treatment.
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Ankara University, Turkey. mdartar@hotmail.com
authors.forename: M D
authors.initials: MD
authors.lastname: Oztan
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002126:Calcium Hydroxide / Q000627:therapeutic use; D002648:Child; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003790:Dental Pulp Necrosis / Q000628:therapy; D005500:Follow-Up Studies; D006171:Gutta-Percha / Q000627:therapeutic use; D006801:Humans; D007180:Incisor / Q000293:injuries / Q000473:pathology; D008297:Male; D008334:Mandible; D010483:Periapical Diseases / Q000382:microbiology / Q000628:therapy*; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D012388:Root Canal Irrigants / Q000627:therapeutic use; D012390:Root Canal Therapy / Q000379:methods; D019227:Tooth Apex / Q000473:pathology; D014945:Wound Healing
chemical_list: D000891:Anti-Infective Agents, Local; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; D006171:Gutta-Percha; C010882:chlorhexidine gluconate; D002126:Calcium Hydroxide; D002710:Chlorhexidine