title: The FEAR factor.
abstract: The decision to exit from mitosis is a fateful one, and Amon and colleagues have shown that it involves both an early and a late component. The FEAR network initiates the exit machinery, while the previously described MEN pathway maintains it.
authors.affiliation: Department of Biological Sciences, University of Pittsburgh, PA 15260, USA.
authors.forename: William S
authors.initials: WS
authors.lastname: Saunders
mesh_terms: D000705:Anaphase / Q000502:physiology*; D002451:Cell Compartmentation; D018797:Cell Cycle Proteins / Q000502:physiology*; D002466:Cell Nucleolus / Q000502:physiology; D018385:Centrosome / Q000502:physiology; D002842:Chromatids / Q000648:ultrastructure; D015825:Chromosomes, Fungal / Q000378:metabolism / Q000648:ultrastructure; D010450:Endopeptidases; D046911:Macromolecular Substances; D008869:Microtubule-Associated Proteins / Q000502:physiology; D017027:Protein Tyrosine Phosphatases; D016601:RNA-Binding Proteins; D029701:Saccharomyces cerevisiae Proteins / Q000502:physiology*; D064247:Separase; D008941:Spindle Apparatus / Q000502:physiology
chemical_list: C074860:CDC14 protein, S cerevisiae; C513239:CEF1 protein, S cerevisiae; D018797:Cell Cycle Proteins; D046911:Macromolecular Substances; D008869:Microtubule-Associated Proteins; D016601:RNA-Binding Proteins; D029701:Saccharomyces cerevisiae Proteins; C437104:Slk19 protein, S cerevisiae; D017027:Protein Tyrosine Phosphatases; D010450:Endopeptidases; D064247:Separase