title: FtsK: Maxwell's Demon?
abstract: FtsK, which links chromosome segregation and cell division in E. coli, has now been shown to be an ATP-dependent DNA translocase. It also activates XerCD-dependent recombination, converting chromosome dimers into monomers, by switching the order of strand cleavage by the recombinase subunits.
authors.affiliation: Institute of Cell and Molecular Biology, University of Edinburgh, Scotland.
authors.forename: William D
authors.initials: WD
authors.lastname: Donachie
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D000705:Anaphase / Q000502:physiology; D001407:Bacillus / Q000502:physiology; D001426:Bacterial Proteins / Q000502:physiology; D002876:Chromosomes, Bacterial / Q000378:metabolism* / Q000648:ultrastructure; D004254:DNA Nucleotidyltransferases / Q000502:physiology; D004269:DNA, Bacterial / Q000378:metabolism*; D004926:Escherichia coli / Q000502:physiology; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000502:physiology*; D019426:Integrases; D008565:Membrane Proteins / Q000737:chemistry / Q000502:physiology*; D011487:Protein Conformation; D045522:Recombinases; D011995:Recombination, Genetic; D012808:Sigma Factor; D014157:Transcription Factors
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; C096452:FtsK protein, E coli; D008565:Membrane Proteins; D045522:Recombinases; D012808:Sigma Factor; D014157:Transcription Factors; C092468:spoIIR protein, Bacillus subtilis; C030069:spore-specific proteins, Bacillus; D000255:Adenosine Triphosphate; D004254:DNA Nucleotidyltransferases; D019426:Integrases; C115006:integron integrase IntI1