title: Intravesical epirubicin treatment following TUR in superficial bladder tumours.
abstract: OBJECTIVE
  To evaluate the effectiveness and tolerability of intravesical epirubicin treatment to prevent recurrence and progression of superficial bladder tumor after TUR.
  
  
  METHODS
  44 patients with superficial bladder tumor, 28 primary and 16 recurrent cases were given 50 mg intravesical epirubicin once a week for 8 weeks after TUR. Recurrent cases had not been treated by any intravesical agent before. Follow-up was done by cystoscopy, urine cytology and random biopsies.
  
  
  RESULTS
  Local recurrence after treatment was found in 14.28% and 18.75%, and recurrence in another area was found in 21.42% and 31.25% of the primary and recurrent tumor groups respectively. Total recurrence in both groups was 40.91%. No systemic toxicity was observed and local side effects were treated symptomatically.
  
  
  CONCLUSIONS
  Intravesical epirubicin after TUR for superficial bladder tumors especially for the primary ones, is a reliable method that provides effective prophylaxis with tolerable side effects.
authors.affiliation: S.S.K. Ankara Hospital 1, Urology Clinic, Ankara, Turkey. mai2603@superonline.com
authors.forename: M A
authors.initials: MA
authors.lastname: Imamoğlu
authors.forename: H
authors.initials: H
authors.lastname: Bakirtaş
authors.forename: O
authors.initials: O
authors.lastname: Yiğitbaşi
authors.forename: H
authors.initials: H
authors.lastname: Ersoy
authors.forename: A N
authors.initials: AN
authors.lastname: Sertçelik
mesh_terms: D000283:Administration, Intravesical; D000328:Adult; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000517:prevention & control* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D015251:Epirubicin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000517:prevention & control*; D011182:Postoperative Care; D014521:Urethra; D001749:Urinary Bladder Neoplasms / Q000517:prevention & control* / Q000601:surgery; D013520:Urologic Surgical Procedures
chemical_list: D000903:Antibiotics, Antineoplastic; D015251:Epirubicin