title: Analyses of the roles of the three cheA homologs in chemotaxis of Vibrio cholerae.
abstract: The Vibrio cholerae genome revealed the presence of multiple sets of chemotaxis genes, including three cheA gene homologs. We found that the cheA-2, but not cheA-1 or cheA-3, gene is essential for chemotaxis under standard conditions. Loss of chemotaxis had no effect on virulence factor expression in vitro.
authors.affiliation: Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
authors.forename: Khoosheh K
authors.initials: KK
authors.lastname: Gosink
authors.forename: Reiji
authors.initials: R
authors.lastname: Kobayashi
authors.forename: Ikuro
authors.initials: I
authors.lastname: Kawagishi
authors.forename: Claudia C
authors.initials: CC
authors.lastname: Häse
mesh_terms: D001426:Bacterial Proteins; D002633:Chemotaxis; D017353:Gene Deletion; D005798:Genes, Bacterial; D005816:Genetic Complementation Test; D015151:Immunoblotting; D008565:Membrane Proteins / Q000032:analysis / Q000235:genetics / Q000378:metabolism*; D000072236:Methyl-Accepting Chemotaxis Proteins; D014734:Vibrio cholerae / Q000378:metabolism* / Q000472:pathogenicity; D014774:Virulence
chemical_list: D001426:Bacterial Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins