[Characteristics of arrhythmia and late ventricular potentials in patients with cardiological syndrome X].
OBJECTIVE
A comparative study of late ventricular potentials (LVP) in patients with cardiological syndrome X (SX) and stenotic atherosclerosis of coronary arteries (ACA) as well as their relations with arrhythmia, cardiac contractility, lipid metabolism and morphological characteristics of the myocardium.


METHODS
The examination of 52 SX and 77 ACA patients as well as 17 healthy subjects included coronaroventriculography, bicycle exercise, 24-h ECG monitoring, echocardiography, signal-averaged high-resolution (SAHR) ECG, investigation of blood lipoproteins. Endomyocardial biopsy was made in 5 ACA and 5 SX patients.


RESULTS
No differences were registered between SX and ACA patients by frequency and severity of arrhythmic episodes, percentage of patients with registered LVP, quantitative parameters of SAHR ECG. Frequency of high-gradation ventricular arrhythmia episodes was significantly higher in SX and ACA patients with LVP than such patients free of LVP. SX patients had correlation between parameters of SAHR ECG, myocardial contractility and lipid metabolism. Foci of diffuse cardiosclerosis are most probable anatomic substrate of LVP.


CONCLUSIONS
The risk of prognostically unfavourable high-gradation ventricular arrhythmia episodes in SX and ACA patients is the same. LVP may predict severe ventricular arrhythmia episodes both in SX and ACA patients.
Kostin
V I
VI
Guliaeva
E N
EN
Efremov
S D
SD
Bogdanov
O Iu
OIu
Zinchuk
S F
SF
Nikitina
I I
II
Zinchuk
V G
VG
Dolinchik
T R
TR
Bobrysheva
I V
IV
Karpov
R S
RS
D001145:Arrhythmias, Cardiac / Q000150:complications / Q000503:physiopathology*; D003324:Coronary Artery Disease / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D004452:Echocardiography; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D017566:Microvascular Angina / Q000150:complications / Q000378:metabolism / Q000503:physiopathology*; D008875:Middle Aged; D009200:Myocardial Contraction; D009206:Myocardium / Q000473:pathology; D015635:Radionuclide Ventriculography
D008055:Lipids