title: Color Doppler ultrasonography in the differentiation of uterine sarcomas from uterine leiomyomas.
abstract: OBJECTIVE
  The aim of this study was to investigate uterine vascularity in cases of uterine leiomyomas and uterine sarcomas, as well as to determine the efficiency of uterine blood flow analysis in differentiating between them.
  
  
  METHODS
  Transvaginal color and pulsed Doppler findings obtained from 117 patients with histologically proven uterine leiomyoma and 12 with uterine sarcoma were retrospectively assessed.
  
  
  RESULTS
  The mean intratumoral resistance index (RI) and pulsatility index (PI) were significantly lower and the intratumoral peak systolic velocity (PSV) was significantly higher in patients with sarcomas than in patients with uterine leiomyomas. Marked reduction of RI and PI and increased PSV could be found in 14 of the leiomyoma cases which showed large size and/or necrotic, degenerative and inflammatory changes. When a cut-off value of 0.5 for the RI was considered, the detection rate for uterine sarcoma was 67% and the false-positive rate was 11.8%.
  
  
  CONCLUSIONS
  These results suggest that the intratumoral RI detected by color and pulsed Doppler ultrasonography in themselves could be poor for the preoperative differential diagnosis of uterine sarcoma.
authors.affiliation: Department of Obstetrics and Gynaecology, Semmelweis University Medical School, Budapest, Hungary.
authors.forename: I
authors.initials: I
authors.lastname: Szabó
authors.forename: A
authors.initials: A
authors.lastname: Szánthó
authors.forename: L
authors.initials: L
authors.lastname: Csabay
authors.forename: Z
authors.initials: Z
authors.lastname: Csapó
authors.forename: K
authors.initials: K
authors.lastname: Szirmai
authors.forename: Z
authors.initials: Z
authors.lastname: Papp
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D019160:Endosonography / Q000379:methods*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D011336:Probability; D012189:Retrospective Studies; D012509:Sarcoma / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color / Q000379:methods; D014594:Uterine Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology