Mass spectrometric studies of 2-aryl-5-acetylthiazole derivatives.
Electron ionisation mass spectrometry was usefully used to characterize structurally 2-aryl-5-acetylthiazole derivatives in the gas phase. The compounds show characteristic fragmentation pathways depending on the chemical nature of the substituent at position 2, consisting mainly in the cleavage of both the 1,2- and 3,4-bonds of the thiazole ring. Liquid secondary ion mass spectrometry was applied to study the effects of protonation on the gas-phase unimolecular reactions of this class of compound. Tandem mass spectrometric experiments, carried out on molecular and protonated molecular ions, and also on fragment ions produced in the source, allowed the elucidation of gas-phase decompositions of low-internal energy ions.
Giorgi
Gianluca
G
Centro Interdipartimentale di Analisi e Determinazioni Strutturali, Università degli Studi di Siena, Via Aldo Moro, 53100 Siena, Italy. gianluca.giorgi@unisi.it
Salvini
Laura
L
Attanasi
Orazio A
OA
Guidi
Barbara
B
Santeusanio
Stefania
S
D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D013844:Thiazoles / Q000032:analysis / Q000737:chemistry*
D013844:Thiazoles