title: Successful treatment of two dogs with allergic dermatitis by anti-allergic peptides (MS-antigen).
abstract: The effects of non-specific immunotherapy with anti-allergic peptides extracted from the urine of human allergic patients (MS-antigen), in two dogs with allergic dermatitis (AD) have been described. Clinically, severe pruritus accompanied by secondary bacterial pyoderma did not respond to conventional therapy with systemic antibiotics. The first clinical change appeared as a significant reduction in pruritus within 3 months, around the time of the 15th injection in both cases. The clinical condition was stabilized after 5 months, allowing the gradual withdrawal of concurrent therapies and an increase of injection intervals. The correlation between the results of intradermal skin tests before and after treatment and the improvement of clinical signs was not obvious.
authors.affiliation: Gifu University, Veterinary Medical Teaching Hospital, Japan.
authors.forename: Song-Jung
authors.initials: SJ
authors.lastname: Park
authors.forename: Naoko
authors.initials: N
authors.lastname: Yoshida
authors.forename: Koji
authors.initials: K
authors.lastname: Nishifuji
authors.forename: Maiko
authors.initials: M
authors.lastname: Sekiguchi
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Momoi
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Fukada
authors.forename: Toshiroh
authors.initials: T
authors.lastname: Iwasaki
mesh_terms: D000818:Animals; D000941:Antigens / Q000627:therapeutic use*; D003876:Dermatitis, Atopic / Q000276:immunology / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs; D006801:Humans; D007167:Immunotherapy / Q000662:veterinary*; D008297:Male; D010455:Peptides / Q000276:immunology*; D011537:Pruritus / Q000276:immunology / Q000662:veterinary
chemical_list: D000941:Antigens; D010455:Peptides