title: Chronic eosinophilic perimyositis with persistent myalgias.
abstract: A 43-year-old man with an 8-year history of hypereosinophilia was evaluated for persistent muscle pain. Methotrexate and corticosteroids were ineffective. Examination, limited by pain even with passive motion, showed only mild weakness. Electromyography and muscle enzymes were normal. A needle muscle biopsy specimen revealed eosinophilic perimyositis. This case illustrates that the diagnosis of eosinophilic perimyositis requires histopathological evaluation, which should be pursued in patients with eosinophilia and persistent myalgia despite normal electromyography and muscle enzymes.
authors.affiliation: Department of Neurology, University of Pittsburgh School of Medicine, BST South, Room S515, Pittsburgh, Pennsylvania 15213, USA.
authors.forename: Sasa A
authors.initials: SA
authors.lastname: Zivkovic
authors.forename: David
authors.initials: D
authors.lastname: Lacomis
authors.forename: Paula R
authors.initials: PR
authors.lastname: Clemens
mesh_terms: D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D004576:Electromyography; D004802:Eosinophilia / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008297:Male; D009220:Myositis / Q000150:complications* / Q000473:pathology*; D010146:Pain / Q000209:etiology* / Q000473:pathology