Definition of intracellular pathogens.
Most microorganisms are destroyed by the host tissues through processes which usually involve phagocytosis and lysosomal disruption. However, some organisms are capable of growing inside macrophages and avoiding destruction. This paper describes the normal phagocytic process and how it is avoided by certain viruses, bacteria and protozoa, and the complex cycle of intracellular replication by species of Chlamydia.
Orfila
Jeanne
J
Laboratoire de Bactériologie---Immunologie Générale, Centre Hospitalier Régional d'Amiens, France.