Unilateral choanal atresia in identical twins: case report and literature review.
Choanal atresia is postulated to be secondary to an abnormality of the rupture of the buccopharyngeal membrane during the embryological period. This condition usually occurs sporadically, but has been described in siblings and successive generations. The genetics remain unclear. We present monozygotic twins with identical findings of unilateral choanal atresia and no other associated anomalies. To our knowledge, this is the first report of such an occurrence.
Chia
Stanley H
SH
Division of Otolaryngology, University of California San Diego Medical Center, 200 W. Arbor Drive #8891, San Diego 92103, USA. stanchia@yahoo.com
Carvalho
Daniela S
DS
Jaffe
Debra M
DM
Pransky
Seth M
SM
D000477:Alkylating Agents / Q000627:therapeutic use; D002648:Child; D002754:Choanal Atresia / Q000175:diagnosis / Q000235:genetics / Q000601:surgery; D004200:Diseases in Twins; D004724:Endoscopy; D006801:Humans; D008297:Male; D016685:Mitomycin / Q000627:therapeutic use; D013517:Otorhinolaryngologic Surgical Procedures; D014057:Tomography, X-Ray Computed; D014430:Twins, Monozygotic
D000477:Alkylating Agents; D016685:Mitomycin