Expedient, stereocontrolled synthesis of (+)-compactin lactone via intramolecular Reformatsky reaction.
A concise, stereodefined synthesis of compactin lactone is described. Samarium(II) iodide mediated intramolecular Reformatsky reaction is the key step in the synthesis.
Reddy
P Pratap
PP
Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 300, Republic of China.
Yen
Kwang-Fu
KF
Uang
Biing-Jiun
BJ