title: [Therapeutic effect of gefin, a new antiviral drug, in experimental genital herpes ].
abstract: Antiviral activity of Gefin was studied in guinea pigs infected with herpes simplex virus (HSV-2). Up to 54.9% animals challenged with HSV survived after 7-day treatment with Gefin (3 local applications a day). The prospects of further trials of the drug in HSV genital herpes are discussed.
authors.forename: L M
authors.initials: LM
authors.lastname: Alimbarova
authors.forename: I F
authors.initials: IF
authors.lastname: Barinskiĭ
authors.forename: K K
authors.initials: KK
authors.lastname: Kuz'min
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D004195:Disease Models, Animal; D017245:Foscarnet / Q000627:therapeutic use*; D006168:Guinea Pigs; D006558:Herpes Genitalis / Q000188:drug therapy*; D018258:Herpesvirus 2, Human; D008297:Male
chemical_list: D000998:Antiviral Agents; D017245:Foscarnet