[Comparison of invasive diagnostic techniques and revascularization therapy of acute coronary syndrome in Hungarian and international databases].
INTRODUCTION, AIMS, METHODS: The databases of large multicentric trials dealing with acute coronary syndrome (OASIS Registry, CORE, PURSUIT, FRAX.I.S.) were analysed.


RESULTS
Significant differences were disclosed comparing the baseline and history characteristics of patients randomized from Eastern or Western Europe. In most investigations the patients from Eastern Europe had a higher prevalence of hypertension, diabetes, angina and myocardial infarction. Invasive diagnostics and revascularization therapy were less frequently used in Eastern than in Western Europe in all the trials. The prevalence of myocardial infarction and the case fatality rate were not uniformly different during the early days, but after 30 days the case fatality rate in Eastern Europe was significantly higher than in Western Europe.


CONCLUSIONS
It is suggested that the differences in demographic and baseline characteristics were only partially responsible for the difference in mortality. The low intervention rate and delayed revascularization may contribute to the high rate of myocardial infarction and mortality in Eastern Europe.
Keltai
Mátyás
M
Altanános Orvostudományi Kar, Kardiológiai Tanszék, Gottsegen György Országos Kardiológiai Intézet, Semmelweis Egyetem, Budapest.
Márkus
Rita
R
Sitkei
Eva
E
Zorándi
Agnes
A
D000208:Acute Disease; D015906:Angioplasty, Balloon, Coronary / Q000706:statistics & numerical data; D001315:Australia / Q000453:epidemiology; D002986:Clinical Trials as Topic; D017023:Coronary Angiography / Q000706:statistics & numerical data; D001026:Coronary Artery Bypass / Q000706:statistics & numerical data; D003327:Coronary Disease / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D016208:Databases, Factual; D048909:Diabetes Complications; D003935:Diagnostic Techniques, Cardiovascular / Q000706:statistics & numerical data*; D005060:Europe / Q000453:epidemiology; D005061:Europe, Eastern / Q000453:epidemiology; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D006973:Hypertension / Q000150:complications; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy; D009204:Myocardial Revascularization / Q000706:statistics & numerical data*; D016032:Randomized Controlled Trials as Topic; D012907:Smoking / Q000009:adverse effects; D013577:Syndrome; D013997:Time Factors; D014481:United States / Q000453:epidemiology