title: [Factors contributing to roquefortine yield variability during cultivation of penicillium roquefortii].
abstract: Variability in the roquefortine yield was shown to be associated with its consumption by the mycelium during isolation of the end product, which depended on temperature, time of culture liquid storage, and biomass concentration. This was also related to the presence in chloroform of chlorocarbonic acid ethyl ester that reacted with roquefortine.
authors.affiliation: Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow Oblast, 142290 Russia.
authors.forename: D M
authors.initials: DM
authors.lastname: Boĭchenko
authors.forename: N F
authors.initials: NF
authors.lastname: Zelenkova
authors.forename: N G
authors.initials: NG
authors.lastname: Vinokurova
authors.forename: B P
authors.initials: BP
authors.lastname: Baskunov
mesh_terms: D002725:Chloroform / Q000737:chemistry; D004873:Ergolines / Q000032:analysis / Q000737:chemistry / Q000378:metabolism*; D005561:Formates / Q000737:chemistry; D006576:Heterocyclic Compounds, 4 or More Rings; D007211:Indoles; D015394:Molecular Structure; D025282:Mycelium / Q000378:metabolism; D009183:Mycotoxins / Q000032:analysis / Q000378:metabolism*; D010407:Penicillium / Q000254:growth & development / Q000378:metabolism*; D010879:Piperazines; D013696:Temperature; D013997:Time Factors
chemical_list: D004873:Ergolines; D005561:Formates; D006576:Heterocyclic Compounds, 4 or More Rings; D007211:Indoles; D009183:Mycotoxins; D010879:Piperazines; C083354:chlorocarbonic acid; C012536:roquefortine; D002725:Chloroform