Molecular epidemiology of TTV-like mini virus in Norway.
TT virus (TTV), the first human circovirus to be discovered, appears to be present in most people; less is known about the prevalence of the related TTV-like mini virus (TLMV). A sensitive nested PCR, specific for TLMV, detected the virus in 48% of 201 sera (Norwegian blood donors) previously found to have a 90% prevalence of TTV. More samples were either positive for both or negative for both viruses than what would have been expected from a random distribution (p = 0.08). Sequence analysis revealed considerable heterogeneity of Norwegian TLMV as compared to international sequences, suggesting that TLMV is efficiently dispersed in human populations.
Moen
E M
EM
Department of Virology, National Institute of Public Health, Oslo, Norway.
Huang
L
L
Grinde
B
B
D001782:Blood Donors; D018173:Circoviridae Infections / Q000453:epidemiology* / Q000821:virology*; D017925:Circovirus / Q000235:genetics* / Q000302:isolation & purification; D004279:DNA, Viral / Q000097:blood; D006801:Humans; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D009664:Norway / Q000453:epidemiology; D017422:Sequence Analysis, DNA
D004279:DNA, Viral