title: Gastroduodenal ulceration in cats: eight cases and a review of the literature.
abstract: Gastroduodenal ulceration (GU) and blood loss was diagnosed in eight cats and compared with 25 previously reported cases of feline GU. Cats with GU presented in a critical condition. Clinical signs consistent with gastrointestinal bleeding were infrequently identified although anaemia was a common finding. Non-neoplastic causes of feline GU tended to have a shorter clinical course with ulcers confined to the stomach. Conversely, cats with tumour-associated GU usually had a more protracted clinical course, weight loss, and ulcers located in the stomach for gastric tumours and the duodenum for extra-intestinal tumours. In this series, definitive diagnosis was possible for cats with neoplasia (gastric tumours and gastrinoma), however, it was difficult to precisely identify the underlying aetiology in cats with non-neoplastic GU. Prompt stabilisation with a compatible blood transfusion, surgical debridement or resection, antibiotic and antiulcer therapy, and treatment of the underlying disease, if identified, was successful in the majority of cases. The prognosis for cats with appropriately managed GU depended on the underlying aetiology, but even cats with neoplasia could be successfully palliated for prolonged periods.
authors.affiliation: University Veterinary Centre Sydney, Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia.
authors.forename: J M
authors.initials: JM
authors.lastname: Liptak
authors.forename: G B
authors.initials: GB
authors.lastname: Hunt
authors.forename: V R D
authors.initials: VR
authors.lastname: Barrs
authors.forename: S F
authors.initials: SF
authors.lastname: Foster
authors.forename: P L C
authors.initials: PL
authors.lastname: Tisdall
authors.forename: C R
authors.initials: CR
authors.lastname: O'Brien
authors.forename: R
authors.initials: R
authors.lastname: Malik
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D001803:Blood Transfusion / Q000662:veterinary; D002371:Cat Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D002415:Cats; D003937:Diagnosis, Differential; D004638:Emergency Treatment / Q000662:veterinary; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000150:complications / Q000628:therapy / Q000662:veterinary*; D008297:Male; D010437:Peptic Ulcer / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents