Idiopathic thrombocytopenia in Japanese black cattle.
A female Japanese Black cow showed hemorrhage under the mucous membrane of the eye conjunctiva and the vagina, and thrombocytopenia in peripheral blood. The clinical manifestations repeated spontaneously during long-term observation. The clinical findings were stable except for severe periodic bleeding. Prothrombin time, activated partial thromboplastin time and fibrinogen levels were normal. The anti-platelet antibody in the serum was analyzed by indirect platelet coagulation tests. Because the platelets in the micro-plate wells of the subject series showed coagulation up to 1:128, it was judged that anti-platelet antibody was present in the serum. A number of megakaryocytes were recognized in smear samples obtained from bone marrow of the scapula immediately after euthanasia. Therefore, this case was diagnosed as idiopathic thrombocytopenia.
Yasuda
Jun
J
Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Japan.
Okada
Keiji
K
Sato
Jun
J
Sato
Reeko
R
Tachibana
Yuko
Y
Takashima
Keisuke
K
Naito
Yoshihisa
Y
D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000097:blood; D001780:Blood Coagulation Tests / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000473:pathology* / Q000628:therapy; D003229:Conjunctival Diseases / Q000473:pathology / Q000628:therapy / Q000662:veterinary; D017809:Fatal Outcome; D005260:Female; D006406:Hematoma / Q000473:pathology / Q000628:therapy / Q000662:veterinary; D006470:Hemorrhage / Q000662:veterinary; D013921:Thrombocytopenia / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D014623:Vaginal Diseases / Q000473:pathology / Q000628:therapy / Q000662:veterinary
D000888:Antibodies, Anti-Idiotypic