title: [Role of disrupting the antioxidant status of the body in forming the endogenous intoxication syndrome in patients with toxic and terminal stages of peritonitis].
abstract: Fifty-one patients with diffuse peritonitis were treated. 40 of these presented with the toxic stage and 11 had terminal stage with lethal outcomes. Studies of the antioxidant status showed an important role of lipid peroxidation metabolites in the formation of endogenous intoxication during the early postoperative period, manifesting, among other things, by decreased albumin transporting function. Analysis of correlations showed some relationships in the studied parameters which can be used in complex with other values in clinical laboratory diagnosis of endotoxicosis severity in peritonitis and in evaluation of the time course of this condition during intensive care. It can serve as a prognostic criterion of peritonitis development and outcome.
authors.forename: V G
authors.initials: VG
authors.lastname: Vasil'kov
authors.forename: L G
authors.initials: LG
authors.lastname: Shikunova
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Kelina
authors.forename: N V
authors.initials: NV
authors.lastname: Bezruchko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D010538:Peritonitis / Q000378:metabolism* / Q000473:pathology; D018805:Sepsis / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology
chemical_list: D000975:Antioxidants