title: [Role of antibiotic prophylaxis in ambulatory cystoscopy].
abstract: BACKGROUND
  There has been a great deal of discussion regarding the necessity of antibiotic prophylaxis in transurethral cystoscopy. In order to clarify this complicated issue, a randomized prospective study was performed on 126 patients planned for cystoscopy.
  
  
  METHODS
  126 patients who underwent urethrocystoscopy and did not have pyuria and bacteriuria were included and divided randomly into 2 groups: group 1 received 400 mg of norfloxacine and group 2 nothing. Urinalysis were performed on all patients 3 days after the examination. Statistical analyses were performed using Chi 2 test and the level of significance was set at 5%.
  
  
  RESULTS
  The global rate of infection was 5%. In the group 1 the incidence of infection was 3% (2/67) vs 5.1% (5/59) in group 2. There were no significant differences in the incidence in the background factor between the 2 groups of patients (p > 0.05).
  
  
  CONCLUSIONS
  Prophylactic administration of antibiotic before cystoscopy does not decrease the incidence of urinary tract incidence and it is not necessarily in patients with sterile urine.
authors.affiliation: Service d'Urologie, CHU Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes.
authors.forename: T
authors.initials: T
authors.lastname: Karmouni
authors.forename: K
authors.initials: K
authors.lastname: Bensalah
authors.forename: A
authors.initials: A
authors.lastname: Alva
authors.forename: J J
authors.initials: JJ
authors.lastname: Patard
authors.forename: B
authors.initials: B
authors.lastname: Lobel
authors.forename: F
authors.initials: F
authors.lastname: Guillé
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000556:Ambulatory Surgical Procedures; D019072:Antibiotic Prophylaxis; D003558:Cystoscopy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014552:Urinary Tract Infections / Q000209:etiology / Q000517:prevention & control*