Progressive intrathoracic lymphadenopathy: EBV associated non-Hodgkin's lymphoma.
A 30 year old man presented with late stage HIV disease and intrathoracic lymphadenopathy. Histology of a mediastinal biopsy suggested infective follicular hyperplasia or a peripheral T cell lymphoma. Subsequently, Epstein-Barr virus (EBV) infection was demonstrated in lymphocytes in the biopsy. Later, hepatosplenomegaly and peripheral lymphadenopathy developed. Histology of a cervical lymph node biopsy showed EBV associated diffuse large B cell (non-Hodgkin's) lymphoma.
Miller
R F
RF
Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, University College London, UK.
Jones
E L
EL
Duddy
M J
MJ
Shahmanesh
M
M
D017088:AIDS-Related Opportunistic Infections / Q000150:complications*; D000328:Adult; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D006529:Hepatomegaly / Q000821:virology; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000821:virology*; D016393:Lymphoma, B-Cell / Q000821:virology*; D008297:Male; D013163:Splenomegaly / Q000821:virology