Does recycling in germinal centres exist?
A general criterion is formulated to decide if the recycling of B cells exists in germinal centre (GC) reactions. The criterion is independent of the selection and affinity maturation process and based solely on total centroblast population arguments. An experimental test is proposed to verify whether the criterion is fulfilled.
Meyer-Hermann
Michael
M
Institut für TheoretischePhysik, Dresden, Germany. meyer-hermann@physik.tu-dresden.de
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D018858:Germinal Center / Q000276:immunology*