title: Asymmetric synthesis of beta-amino alcohols by reductive cross-coupling of benzylideneamine with planar chiral benzaldehydes.
abstract: [reaction: see text] Samarium iodide mediated reductive cross-coupling of N-tosyl benzylideneamine with benzaldehydes or the corresponding chromium complexes gave syn-beta-amino alcohol derivatives. A dynamic kinetic resolution of a configurationally equilibrated reactive species occurred in the cross-coupling with planar chiral benzaldehyde chromium complexes.
authors.affiliation: Department of Chemistry, Faculty of Integrated Arts and Sciences, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
authors.forename: Yoshie
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Taniguchi
authors.forename: Motokazu
authors.initials: M
authors.lastname: Uemura
mesh_terms: D000588:Amines / Q000737:chemistry; D000605:Amino Alcohols / Q000138:chemical synthesis*; D001547:Benzaldehydes / Q000737:chemistry; D001597:Benzylidene Compounds / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000588:Amines; D000605:Amino Alcohols; D001547:Benzaldehydes; D001597:Benzylidene Compounds; D003432:Cross-Linking Reagents