title: [Wilm's tumor. Diagnostic capacities of magnetic resonance imaging. MRI-pathomorphological comparison].
abstract: The accuracy of magnetic resonance imaging (MRI) in the diagnosis of Wilms' tumor (WT) and in the evaluation of preoperative chemotherapy (PCH) efficiency was investigated and compared with histopathological data of 56 children and infants with proven retroperitoneum neoplasma (WT--49, neuroblastoma--6, congenital mesoblastic nephroma--1). The author described the WT MRI-semiotics in general and in particular for its changes during the preoperative chemotherapy. The formula for calculation of tumor reduction index is suggested. The MRI sensitivity (100%), specificity (77.8%) and accuracy (91.1%) are detected. The high positive correlation level between the MRI and pathologic findings, concerning WT dimensions, pseudocapsule presence and safety, tumor structure secondary alterations and tumor spreading was found. At the same time, the specific MRI criteria for the different histological types of WT were not found. MRI is confirmed to be an accurate tool for diagnostic monitoring of patients with WT and other retroperitoneum neoplasms.
authors.affiliation: Rostov State Medical University, Ministry of Health of the Russian Federation.
authors.forename: V
authors.initials: V
authors.lastname: Dombrovskii
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D012680:Sensitivity and Specificity; D009396:Wilms Tumor / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology