[Current status of complete remission rate of acute leukemia in Shanghai].
OBJECTIVE
To investigate the treatment outcome in newly diagnosed acute leukemia patients.


METHODS
Two thousand five hundred and eighteen patients with acute leukemia registered in Shanghai were retrospectively analyzed.


RESULTS
and


CONCLUSIONS
The overall complete remission (CR) rate of acute leukemia was 60.4%: 51% for acute myeloid leukemia (AML) and 76.7% for acute lymphoid leukemia (ALL). CR rate of childhood ALL was 87.1%, while of elderly AML only 26%. Between 1984 and 1994, CR rates of AML and of ALL were not increased except for that of AML-M(3). Induction regimen was associated with CR rate. All-transretinoic acid was effective for AML-M(3). The VDLP and VDP regimens were more effective than that of VP regimen for ALL patients. There was no significant difference in CR rate between DA and HA regimens for treatment of ALL patients.
D000328:Adult; D000367:Age Factors; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D012074:Remission Induction; D012189:Retrospective Studies