Effect of gaseous media on the balance between cardiac outputs of the right and left ventricles.
Acute experiments on cats showed that mild hypoxia did not disturb the balance between right and left ventricular outputs. Breaching 3% O(2) shifted this balance by reducing right ventricular output in cats with low resistance to hypoxia. Spontaneous breathing hypercapnic gas mixtures shifted this balance towards the left ventricular output. During artificial ventilation under open chest conditions, hypercapnia induced opposite changes and shifted the balance towards the right ventricular output.
Sanotskaya
N V
NV
Laboratory of Respiratory Pathophysiology, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow.
Matsievskii
D D
DD
D000818:Animals; D001011:Aorta / Q000502:physiology; D002415:Cats; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D006352:Heart Ventricles / Q000187:drug effects*; D006439:Hemodynamics; D006632:Histamine / Q000494:pharmacology; D000860:Hypoxia; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009638:Norepinephrine / Q000494:pharmacology; D010100:Oxygen / Q000378:metabolism; D013997:Time Factors; D014662:Vasoconstrictor Agents / Q000494:pharmacology; D016276:Ventricular Function
D014662:Vasoconstrictor Agents; D006632:Histamine; D010100:Oxygen; D009638:Norepinephrine; D004837:Epinephrine