title: Critical illness as a model of hypothalamic ageing.
abstract: In this review we shall consider the endocrine changes seen in the various hypothalamic pituitary-target gland axes at different stages of critical illness and conclude by comparing these changes with those seen in the normal ageing process.
authors.affiliation: Department of Intensive Care Medicine, University Hospital, Gasthuisberg, Catholic University of Leuven, Belgium.
authors.forename: Greet
authors.initials: G
authors.lastname: Van den Berghe
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Shalet
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D016638:Critical Illness; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism*; D007986:Luteinizing Hormone / Q000378:metabolism; D008954:Models, Biological; D010913:Pituitary-Adrenal System / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism; D013739:Testosterone / Q000378:metabolism; D013961:Thyroid Gland / Q000378:metabolism; D013972:Thyrotropin / Q000378:metabolism
chemical_list: D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D013972:Thyrotropin; D013006:Growth Hormone