Synthesis and photophysical properties of new conjugated fluorophores designed for two-photon-excited fluorescence.
[structure: see text] Novel elongated push-push fluorophores (e.g., 9) were synthesized by 2-fold Sonogashira or Wittigminus signHorner reactions. Modulation of the length and topology of the conjugated connectors allows tuning of their photophysical properties. In addition, their photoluminescence can be adjusted by playing on polarity. Derivatives combining enhanced two-photon absorption cross section (sigma2) in the visible red and high fluorescence quantum yield (Phi) have been obtained. Such fluorophores hold promise for nonlinear imaging of biological systems.
Mongin
Olivier
O
Synthèse et ElectroSynthèse Organiques (CNRS, UMR 6510), Université de Rennes 1, Campus de Beaulieu, Bât. 10A, F-35042 Rennes Cedex, France.
Porrès
Laurent
L
Moreaux
Laurent
L
Mertz
Jerome
J
Blanchard-Desce
Mireille
M