The alpha-D anomer of 5-aza-7-deaza-2'-deoxyguanosine.
In the monohydrate of 2-amino-8-(2-deoxy-alpha-D-erythro-pentofuranosyl)-8H-imidazo[1,2-a][1,3,5]triazin-4-one, C(10)H(13)N(5)O(4) x H(2)O, denoted (I) or alpha Z(d), the conformation of the N-glycosylic bond is in the high-anti range [chi = 87.5 (3)]. The 2'-deoxyribofuranose moiety adopts a C2'-endo,C3'-exo((2')T(3')) sugar puckering (S-type sugar) and the conformation at the C4'-C5' bond is -sc (trans).
Seela
Frank
F
Laboratorium für Organische und Bioorganische Chemie, Institut für Chemie, Universität Osnabrück, Barbarastrasse 7, 49069 Osnabrück, Germany. frank.seela@uni-osnabrueck.de
Rosemeyer
Helmut
H
Melenewski
Alexander
A
Heithoff
Eva-Maria
EM
Eickmeier
Henning
H
Reuter
Hans
H
D001372:Aza Compounds / Q000737:chemistry*; D003849:Deoxyguanosine / Q000031:analogs & derivatives / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation
C455519:5-aza-7-deaza-2'-deoxyguanosine; D001372:Aza Compounds; D003849:Deoxyguanosine