title: Type 2 diabetes in obese white children.
abstract: We report four white adolescents aged 13 to 15 years (three females, one male) from the south and west region of England who presented with type 2 diabetes mellitus associated with significant obesity (body mass index more than +3SDS) in the past two years. Although these are the first reported obese, white cases from the UK to present with diabetes, we believe this clinical scenario will become more prevalent given the epidemic of childhood obesity in this country.
authors.affiliation: The Royal Hospital for Children, The Paul O'Gorman Building, Upper Maudlin Street, Bristol BS2 8BJ, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Drake
authors.forename: A
authors.initials: A
authors.lastname: Smith
authors.forename: P R
authors.initials: PR
authors.lastname: Betts
authors.forename: E C
authors.initials: EC
authors.lastname: Crowne
authors.forename: J P H
authors.initials: JP
authors.lastname: Shield
mesh_terms: D000293:Adolescent; D001645:Biguanides / Q000627:therapeutic use; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D009765:Obesity
chemical_list: D001645:Biguanides