title: [Relation between Beta-2-glycoprotein I and hepatitis B virus surface antigen].
abstract: OBJECTIVE
  To clarify the binding character between Beta-2-glycoprotein I (Beta-2-GPI) and HBsAg.
  
  
  METHODS
  Beta-2-GPI was purified from human plasma and labelled with biotin. Solid phase enzyme linked absorbance assay was used to investigate its binding with HBsAg.
  
  
  RESULTS
  Biotinylated Beta-2-GPI was found to bind HBsAg and the reaction could be inhibited by excess unlabelled Beta-2-GPI.
  
  
  CONCLUSIONS
  Beta-2-GPI may play a role in hepatitis B virus infection.
authors.affiliation: Department of Internal Medicine, the First Affiliated Hospital, Norman Bethune University of Medical Sciences, Changchun 130021, China.
authors.forename: Pujun
authors.initials: P
authors.lastname: Gao
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Guo
authors.forename: Like
authors.initials: L
authors.lastname: Qu
authors.forename: Tong
authors.initials: T
authors.lastname: Shi
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zhang
authors.forename: Chun'e
authors.initials: C
authors.lastname: Dong
authors.forename: Hanyi
authors.initials: H
authors.lastname: Yang
mesh_terms: D001665:Binding Sites; D019921:Biotinylation; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006023:Glycoproteins / Q000302:isolation & purification / Q000378:metabolism*; D006514:Hepatitis B Surface Antigens / Q000378:metabolism*; D006515:Hepatitis B virus / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D053482:beta 2-Glycoprotein I
chemical_list: D006023:Glycoproteins; D006514:Hepatitis B Surface Antigens; D053482:beta 2-Glycoprotein I