title: Two primary intracranial tumors of different histology: report of a case with a choroid plexus papilloma and a concurrent vestibular schwannoma in the cerebellopontine angle.
abstract: A very rare case of multiple primary intracranial tumors is reported. A 41-year-old female patient was referred for surgery with a cerebellopontine angle (CPA) tumor. Medical history and MRI study showed typical findings of a right acoustic neuroma with a hydrocephalus. Neurological, dermatological, and ocular examinations revealed no evidence of neurofibromatosis. During surgery, a red-colored cauliflower like mass was found in the right CPA. The roof of the fourth ventricle could be seen through the lateral recess after removal of the tumor. Another mass, a 1.5-cm sized schwannoma protruding through the right internal auditory meatus, was removed by the transmeatal approach. Although the tumor masses were in contact and compressed against each other, there was a clear demarcation between them. Histological examination confirmed that the first mass was a typical choroid plexus papilloma with fibrovascular core, and that the second was a schwannoma. The patient recovered without any new neurological deficit. Result of a Medline search indicated that this rare combination of multiple primary tumors has not been reported previously.
authors.affiliation: Department of Neurosurgery, Yongdong Severance Hospital, Yonsei University College of Medicine, Kangnam P.O. Box 1217, Seoul 135-720, Korea. kyusung@yumc.yonsei.ac.kr
authors.forename: Kyu-Sung
authors.initials: KS
authors.lastname: Lee
authors.forename: Eui Kyo
authors.initials: EK
authors.lastname: Seo
mesh_terms: D000328:Adult; D016545:Choroid Plexus Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009442:Neurilemmoma / Q000473:pathology*; D010212:Papilloma / Q000473:pathology*; D000160:Vestibulocochlear Nerve Diseases / Q000473:pathology*