title: [Study on hepatitis C virus genotyping in some parts of China].
abstract: OBJECTIVE
  To study the genotypes of hepatitis C virus in some parts of China.
  
  
  METHODS
  Twenty-seven sera of plasma donors from Guan county of Hebei province, Zhoukou district of Henan province, and 36 patients with chronic hepatitis C from Beijing and Qingdao cities were tested for HCV RNA by Amplicor PCR kit. Thirty-six of 38 HCV RNA positive sera were further genotyped, using INNO-LiP A HCV II kit.
  
  
  RESULTS
  The HCV RNA positive rates of plasma donors and patients with chronic hepatitis C were 48.15% (13/27) and 69.44% (25/36) respectively. Genotyping data from 13 plasma donors and 23 patients with chronic hepatitis C showed that 29 (80.55%) were 1b, 5 (13.89%) were genotype 2, and 2 (5.56%) remained untyped.
  
  
  CONCLUSIONS
  1b seemed to be the prevalent HCV genotype in some parts of China.
authors.affiliation: Department of Microbiology, School of Basic Medicine, Beijing University, Beijing 100083, China.
authors.forename: H
authors.initials: H
authors.lastname: Zhuang
authors.forename: L
authors.initials: L
authors.lastname: Tracy
authors.forename: Y
authors.initials: Y
authors.lastname: Cui
mesh_terms: D005838:Genotype; D016174:Hepacivirus / Q000145:classification* / Q000235:genetics; D019698:Hepatitis C, Chronic / Q000821:virology*; D006801:Humans; D012367:RNA, Viral / Q000097:blood
chemical_list: D012367:RNA, Viral