[Poorly tolerated or genuinely allergic? How to properly assess food allergies].
Massive immune reactions to certain foods may be traced back to immunological, but also to non-immunological mechanisms. The diagnostic work-up must therefore aim to distinguish an allergy from other inflammatory, neoplastic or immunoregulative disorders. The most common form of gastrointestinal-mediated allergy form are the IgE-mediated reactions of the immediate type (Type 1 allergy). The routine diagnostic investigation includes history-taking, a daily diary of foods eaten, skin tests and antibody determination. The diagnosis of an allergy is often complicated by the multitude of possible manifestation sites, a possibly localized effect, and variations in the depth of allergic processes. To confirm the diagnosis, an oral provocative test should always be performed.
Raithel
M
M
Medizinische Klinik I der Universität Erlangen-Nürnberg. Martin.Raithel@med1.imed.uni-erlangen.de
Weidenhiller
M
M
Abel
R
R
Nabe
A
A
Hahn
E G
EG
D000284:Administration, Oral; D000485:Allergens / Q000276:immunology; D000906:Antibodies / Q000097:blood; D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007428:Intradermal Tests; D011852:Radioallergosorbent Test
D000485:Allergens; D000906:Antibodies; D007073:Immunoglobulin E