title: Novel steroidal pyrimidyl inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase).
authors.affiliation: Saarland University, P.O. Box 151150, D-66041 Saarbrücken, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Haidar
authors.forename: P B
authors.initials: PB
authors.lastname: Ehmer
authors.forename: R W
authors.initials: RW
authors.lastname: Hartmann
mesh_terms: D000736:Androstenes; D000737:Androstenols / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D020128:Inhibitory Concentration 50; D007654:Ketoconazole / Q000494:pharmacology; D008297:Male; D013254:Steroid 17-alpha-Hydroxylase / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
chemical_list: D000736:Androstenes; D000737:Androstenols; D004791:Enzyme Inhibitors; D013254:Steroid 17-alpha-Hydroxylase; C089740:abiraterone; D007654:Ketoconazole