title: [Study on the needle biopsies of 100 prostatic adenocarcinoma].
abstract: OBJECTIVE
  To study the morphological diagnostic criteria of prostatic adenocarcinoma in needle biopsy.
  
  
  METHODS
  250 cases of prostatic needle biopsy including 100 cases of adenocarcinoma were observed retrospectively. The diagnostic significance of 20 parameters of morphological criteria including the architectural changes, cytologic features, invasion and some additional histologic features (intraepithelial neoplasm, intraluminal crystelloid body, intraluminal basophilic mucin secretion, collagen nodule and coagulative necrosis) were analyzed.
  
  
  RESULTS
  All 20 parameters of morphological criteria had practical significance in pathologic diagnosis, the most significant ones being architectural changes, prominent nucleoli, perineural and stromal invasion.
  
  
  CONCLUSIONS
  The diagnosis of prostatic adenocarcinoma is based on a constellation of cytologic and architectural features.
authors.affiliation: Department of Pathology, Shanghai Sixth People's Hospital, Shanghai 200233, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Jiang
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.forename: J
authors.initials: J
authors.lastname: Zhou
authors.forename: L
authors.initials: L
authors.lastname: Liu
authors.forename: G
authors.initials: G
authors.lastname: Bian
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology*