title: [Interconnection of immunologic indicators of blood and functional parameters of leukocytes in children with relapsing herpesvirus infection].
abstract: Correlations between immunological indices of blood and functional activity of leukocytes were studied in healthy children and those with recurrent Herpes virus infection (RHVI) at the age 3-6 and 7-11 years. Functional activity of leukocytes was assessed by the chemiluminescence test. Both healthy and RHVI children are shown to have age-specific features of blood immunology, leukocyte function and their correlation. In ontogenesis and RHVI relations between immunological indices of blood and functional parameters of leukocytes vary and correlations appear between leukocyte function and cellular, humoral immunity. These findings evidence for differentiation of ontogenetic processes in different links of immunological system, on the one side, and necessitate development of normal age standards which will facilitate diagnosis of immunoreactive disorders in various infections, on the other side.
authors.forename: A A
authors.initials: AA
authors.lastname: Savchenko
authors.forename: L M
authors.initials: LM
authors.lastname: Kurtasova
authors.forename: N A
authors.initials: NA
authors.lastname: Shakina
authors.forename: G B
authors.initials: GB
authors.lastname: Surgutskaia
mesh_terms: D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D006566:Herpesviridae Infections / Q000097:blood* / Q000276:immunology; D006801:Humans; D007962:Leukocytes / Q000276:immunology*; D012008:Recurrence