[Gena types of Shigella enterotoxins of S. flexneri 2a].
OBJECTIVE
To identify homogenous clones of S. flexneri 2a, using gene distribution polymorphism of Shigella enterotoxin 1 (set 1) and Shigella enterotoxin 2 (set 2) in a Shigellosis outbreak caused by S. flexneri 2a.


METHODS
In addition to field epidemiological investigation, 43 strains of S. flexneri 2a were determined by polymerase chain reaction (PCR).


RESULTS
The 43 strains (1 from food, 1 from a carrier, 41 from patients) were divided into 3 clones (set1 +/set2 + for 39 strains, set1 -/set2 + for 1, set1 +/set2 - for 3 strains).


CONCLUSIONS
This outbreak was caused by S. flexneri 2a. The route of transmission was contaminated-food borne. Some sporadic cases were noticed during the outbreak. The method used in this study was satisfactory to the identification of S. flexneri 2a.
Bai
S
S
Department of Infectious diseases, The 253th Hospital of PLA, Hohhot, 010051, China.
Li
X
X
Xia
G
G
Yuan
H
H
Zheng
W
W
Wang
H
H
D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D004405:Dysentery, Bacillary / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D005838:Genotype; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D022621:Shiga Toxin / Q000235:genetics*; D012763:Shigella flexneri / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
D022621:Shiga Toxin