title: [Cranioplasty using the patient's autogenous bone preserved by freezing--an examination of post-operative infection rates].
abstract: The current technique for cranioplasty using artificial bone requires further improvement with regard to infection, strength and comfort through good fitting. We have carried out cranioplasty using the patient's autogenous bone flap obtained during first surgery. It was immersed in 200 mg of Amikacin Sulphate, and frozen at -16 degrees C until its use in cranioplasty. From 1980 to 1998, cranioplasty has been carried out on 206 patients. They consisted of 118 males and 88 females, and their age ranged in our institute from 1 to 81; average age 51.1. Ruptured aneurysm (48%), head injury (14%), intracranial hemorrhage (23%) and cerebral infarction (12%) were the major causes requiring decompression surgery. We analyse the bone preservation period and the time between cranioplasty and the onset of infection. The infection rates per bone preservation periods, the causes of decompression and age groups are studied. Of the 208 case studies, infection necessitating bone removal or debridement was noted in 8 cases (3.88%). Average bone preservation period in the infected group was 31.1 days as compared with 54.9 days for the non-infected group (p < 0.05). Not patient age but the type of head injury is also a significant factor in post cranioplasty infection.
authors.affiliation: Department of Neurosurgery, Fuji Brain Institute and Hospital, Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Nagayama
authors.forename: Gakushi
authors.initials: G
authors.lastname: Yoshikawa
authors.forename: Ken
authors.initials: K
authors.lastname: Somekawa
authors.forename: Michihiro
authors.initials: M
authors.lastname: Kohno
authors.forename: Hiromu
authors.initials: H
authors.lastname: Segawa
authors.forename: Keiji
authors.initials: K
authors.lastname: Sano
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Shiokawa
authors.forename: Isamu
authors.initials: I
authors.lastname: Saito
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016025:Bone Transplantation; D002648:Child; D002675:Child, Preschool; D015925:Cryopreservation / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D012886:Skull / Q000601:surgery*; D013530:Surgical Wound Infection / Q000453:epidemiology*; D014182:Transplantation, Autologous