title: Review article: the non-inherited gastrointestinal polyposis syndromes.
abstract: The non-inherited gastrointestinal polyposis syndromes represent a group of rare disorders characterized by the presence of multiple, non-adenomatous polyps on the gastrointestinal mucosa occurring in unrelated patients. We present here a review of the clinical and histo- pathological aspects of the syndromes to include the Cronkhite-Canada syndrome, hyperplastic polyposis and lipomatous polyposis. While infrequently encountered, these diseases can have devastating clinical effects that may be aggravated by delays in diagnosis and treatment. Prompt accurate diagnosis and treatment of these uncommon disorders depend on a sound working knowledge of the distinct clinical and pathological features described herein.
authors.affiliation: Department of Internal Medicine and Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL 32224, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: Ward
authors.forename: H C
authors.initials: HC
authors.lastname: Wolfsen
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004338:Drug Combinations; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D006965:Hyperplasia / Q000473:pathology* / Q000628:therapy*; D007417:Intestinal Polyps / Q000473:pathology* / Q000628:therapy*; D018529:Nutritional Support; D013577:Syndrome
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D006633:Histamine Antagonists