Novel steroidal pyrimidyl inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase).
Haidar
S
S
Saarland University, P.O. Box 151150, D-66041 Saarbrücken, Germany.
Ehmer
P B
PB
Hartmann
R W
RW
D000736:Androstenes; D000737:Androstenols / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D020128:Inhibitory Concentration 50; D007654:Ketoconazole / Q000494:pharmacology; D008297:Male; D013254:Steroid 17-alpha-Hydroxylase / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
D000736:Androstenes; D000737:Androstenols; D004791:Enzyme Inhibitors; D013254:Steroid 17-alpha-Hydroxylase; C089740:abiraterone; D007654:Ketoconazole