title: Superior vena cava syndrome.
abstract: Approximately 15,000 cases of superior vena cava (SVC) obstruction are diagnosed in the United States annually. Malignancies (primarily lung cancer) are the underlying cause of 80-85% of cases, leaving 15-20% caused by various benign conditions, including sclerosing mediastinitis (the diagnosis in our case). Thrombolytic therapy and major advances in vascular techniques in recent years have improved the outcome and lessened the morbidity of SVC obstruction. However, even though a benign condition, sclerosing mediastitinis is a dynamic, ongoing fibrotic condition that seldom can be totally removed surgically. It frequently causes recurrent episodes of SVC obstruction, requiring further repetitive vascular procedures that can result in major morbidity and even mortality.
authors.affiliation: Country Life Insurance Company, PO Box 2000, Bloomington, IL 61702-2000, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Bilyeu
mesh_terms: D002637:Chest Pain / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D007352:Insurance, Life; D008297:Male; D008480:Mediastinitis / Q000150:complications / Q000628:therapy; D008875:Middle Aged; D011379:Prognosis; D013479:Superior Vena Cava Syndrome / Q000191:economics / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*