Growth of the fetal lens and orbit.
OBJECTIVE
To present normal lens and orbital measurement ranges by gestational age.


METHODS
Three hundred and thirty-five women with uneventful pregnancies were evaluated from the 15th to the 40th week of gestation. Lens and orbital measurements were added to routine biometric measurements for normal fetuses.


RESULTS
A strong linear correlation was observed between gestational age (GA) and lens diameter (R(2)=0.89; P<0.0001), circumference (R(2)=0.89; P<0.0001), and surface (R(2)=0.90; P<0.0001). A linear correlation was also found between GA and orbital diameter (R(2)=0.92; P<0.0001), circumference (R(2)=0.92; P<0.0001) and surface (R(2)=0.95; P<0.0001). A linear growth function was observed between biparietal diameter and both lens diameter (R(2)=0.90; P<0.0001) and orbital diameter (R(2)=0.94; P<0.0001).


CONCLUSIONS
Lens and orbital measurements provide normative data for fetal growth and development. These data may be also helpful in detecting fetal ocular anomalies.
Dilmen
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G
Department of Radiology, Faculty of Medicine, University of Fatih, Emek, Ankara, Turkey. akoktener@yahoo.com
Köktener
A
A
Turhan
N O
NO
Tez
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S
D005314:Embryonic and Fetal Development; D005123:Eye / Q000196:embryology; D005124:Eye Abnormalities / Q000000981:diagnostic imaging; D005260:Female; D005865:Gestational Age; D006801:Humans; D007908:Lens, Crystalline / Q000033:anatomy & histology / Q000196:embryology*; D009915:Orbit / Q000033:anatomy & histology / Q000196:embryology*; D011247:Pregnancy; D012044:Regression Analysis; D016216:Ultrasonography, Prenatal