title: Synthesis of some A- and D-ring fused steroidal pyrazoles, isoxazoles and pyrimidines.
abstract: The preparation of steroidal heterocycles containing pyrazole, isoxazole and pyrimidine rings fused to the 2,3- and 16,17-positions of the steroid nucleus is described. These were prepared by the reaction of hydrazine, hydroxylamine and guanidine, respectively, with 2-ethoxymethylene-3-oxo- or 16-ethoxymethylene-17-oxo- or 2-bis(methylthio)methylene-3-oxo- or 16-bis(methylthio)methylene-17-oxo-steroids.
authors.affiliation: Department of Chemistry, Manipur University, Canchipur-795 003, Manipur, India. warjeetl@dte.vsnl.net.in
authors.forename: Warjeet S
authors.initials: WS
authors.lastname: Laitonjam
authors.forename: Tombisana S
authors.initials: TS
authors.lastname: Rajkumar
authors.forename: Brajakishor S
authors.initials: BS
authors.lastname: Chingakham
mesh_terms: D019791:Guanidine / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D006834:Hydrazines / Q000737:chemistry; D019811:Hydroxylamine / Q000737:chemistry; D007555:Isoxazoles / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011720:Pyrazoles / Q000138:chemical synthesis*; D011743:Pyrimidines / Q000138:chemical synthesis*; D017550:Spectroscopy, Fourier Transform Infrared; D013256:Steroids / Q000138:chemical synthesis*
chemical_list: D006571:Heterocyclic Compounds; D006834:Hydrazines; D007555:Isoxazoles; D011720:Pyrazoles; D011743:Pyrimidines; D013256:Steroids; C029424:hydrazine; D019811:Hydroxylamine; D019791:Guanidine