title: [Clinical study of 17 patients with cheiro-oral-pedal syndrome].
abstract: BACKGROUND
  To characterize the clinical features, etiology and prognosis in cheiro-oral-pedal syndrome.
  
  
  METHODS
  Descriptive study of 17 patients with cheiro-oral-pedal syndrome included in the Sagrat Cor Hospital of Barcelona Stroke Registry over a 11 year period.
  
  
  RESULTS
  Cheiro-oral-pedal syndrome was present in 6 patients (35%), cheiro-oral syndrome in 10 (59%) and isolated oral syndrome in 1 (6%). Cheiro-oral-pedal syndrome was caused by a lacunar infarct in 88% of patients and by atherotrombotic infarcts in 12%. Cheiro-oral-pedal syndrome accounted for 0.7% of all acute strokes (n = 2.244), 1% of all cerebral infarcts (n = 1.649), 3.5% of all lacunar infarcts (n = 422) and 18.5% of all pure sensory lacunar infarcts (n = 80). Thalamus (n = 13), internal capsule (n = 2), striatocapsular involvement (n = 1) and fronto-parietal involvement (n = 1) were the cerebral topographies. Absence of in hospital mortality and absence or mild neurological deficit at discharge from the hospital were present in all the patients.
  
  
  CONCLUSIONS
  Lacune hypothesis is present in cheiro-oral-pedal syndrome. Cheiro-oral-pedal syndrome was caused by a lacunar infarct in 88% of patients. The thalamic topography is the most frequent and the prognosis in cheiro-oral-pedal syndrome is good.
authors.affiliation: Unidad de Patología Vascular Cerebral, Servicio de Neurología, Hospital del Sagrat Cor, Barcelona, Spain. aarboixd@meditex.es
authors.forename: Adrià
authors.initials: A
authors.lastname: Arboix
authors.forename: Josefina
authors.initials: J
authors.lastname: Tomàs
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020520:Brain Infarction / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome