[Analysis of bone mineral density and relevant factors in 781 healthy people aged 15 to 50].
OBJECTIVE
To determine further the age to form peak bone mass (PBM) and the factor influencing it and bone mineral density (BMD) and to find an effective way to prevent from osteoporosis in the elderly.


METHODS
BMD was measured in 781 people aged 15 to 50 years and relevant factors in lifestyle were investigated. Multivariate regression was used to analyze the relationship between BMD and lifestyles and to identify both risk and benefit factors for osteoporosis.


RESULTS
For every ten-kilogram increase in body weight, BMD at varied sites increased by an amount of 0.028 - 0.056 g/cm(2) for males and 0.050 - 0.086 g/cm(2) for females, respectively. During their adolescence for males, for every increase of one grade in physical exercise, BMD at varied sites increased by an amount of 0.034 - 0.078 g/cm(2) in males and BMD at lumbar vertebra in males aged 15 - 24 correlated negatively with their total amount of alcohol drinking, and that at lumbar vertebra and of the whole body increased by about 0.035 g/cm(2) in females, which correlated negatively with their total amount of cigarette smoking. Female BMD at lumbar vertebra correlated reversely with their age of menarche and correlated positively with their average time of breast feeding.


CONCLUSIONS
Increase in physical exercise during puberty could increase PBM for the adolescents and keeping adequate body weight and reducing cigarette smoking and alcohol drinking would benefit for the prevention from age-related osteoporosis.
Qin
L
L
Department of Isotope Research, Sino-Japanese Friendship Hospital, Beijing 100029.
Chen
J
J
Ge
C
C
Ma
H
H
Zhang
W
W
Xiao
Y
Y
Bao
A
A
D015502:Absorptiometry, Photon; D000328:Adult; D001835:Body Weight; D015519:Bone Density; D015444:Exercise; D005260:Female; D006801:Humans; D008019:Life Style; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010024:Osteoporosis / Q000517:prevention & control; D012016:Reference Values; D012044:Regression Analysis; D012494:Sampling Studies; D011795:Surveys and Questionnaires