title: Pityriasis versicolor rubra.
abstract: We report six typical cases with pityriasis versicolor (PV) rubra, with a background of collagen diseases in five cases and none in one case. Two cases of systemic lupus erythematosus (SLE) and one case of systemic scleroderma (SSc) had both PV rubra and nigra on the trunk. Diagnosis of superficial infections of PV was made by microscopic examination of skin scrapings following KOH, and many small whitish colonies were obtained in Sabouraud's slant agar medium culture containing cycloheximide with olive oil in all cases. Malassezia sympodialis was isolated from the scales of two different lesions at a 6 week-interval in a same person (a 32 year-old male without SLE nor SSc) by the method of Makimura et al. [5], although the other five cases were not examined for the isolation. Histopathological features of the lesion on the dorsum of the trunk showed no epidermal hyperplasia without elongation of rete ridges and no inflammatory cell infiltration in the dermis, however there was only dilatation of small blood vessels in the dermis, which was reconfirmed capillaroscopically. In the horny layers, several yeastlike and fine filamentous structures were seen which were positive with PAS and Grocott stains. Both clinical and histological features led us to speculate PV rubra. All the patients were treated with anti-fungal ointment, and the lesions diminished in less than 2 weeks. No recurrence has been seen in any of the cases. This PV rubra may be independent from PV nigra, although Horiuchi [2] suggested the earlier lesion occurs in advance of PV alba or nigra.
authors.affiliation: Department of Dermatology, Prefectural Gifu Hospital, 4-6-1 Noishiki, Gifu City, 500-8717, Japan.
authors.forename: Manubu
authors.initials: M
authors.lastname: Maeda
authors.forename: Koi Chi
authors.initials: KC
authors.lastname: Makimura
authors.forename: Hideyo
authors.initials: H
authors.lastname: Yamaguchi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008290:Malassezia / Q000302:isolation & purification*; D008297:Male; D008825:Miconazole / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications; D012867:Skin / Q000382:microbiology; D013684:Telangiectasis / Q000209:etiology* / Q000503:physiopathology; D014010:Tinea Versicolor / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology
chemical_list: D008825:Miconazole; C020382:isoconazole