title: [Functional activity of endotoxin binding factors in chronic viral hepatitis B and C].
abstract: The functional state of cell-mediated and humoral antiendotoxin factors in patients with chronic viral hepatitides B and C has been studied. A decreased content of antibodies to glycolipid of chemotype Re and to Escherichia coli O14 with common enterobacterial antigen was shown to occur in these diseases. In addition, a decreased number of neutrophils, eosinophils and thrombocytes has been noted. The conclusion has been made that patients with chronic hepatitides are not protected from the pathogenic action of endotoxin penetrating from the intestines into the systemic blood stream.
authors.affiliation: State Medical University, Research Institute of Epidemiology and Microbiology, Kazan, Russia.
authors.forename: A S
authors.initials: AS
authors.lastname: Sozinov
authors.forename: I A
authors.initials: IA
authors.lastname: Anikhovskaia
authors.forename: D Sh
authors.initials: DSh
authors.lastname: Enaleeva
authors.forename: O D
authors.initials: OD
authors.lastname: Zinkevich
authors.forename: V G
authors.initials: VG
authors.lastname: Likhoded
authors.forename: I M
authors.initials: IM
authors.lastname: Salakhov
authors.forename: S V
authors.initials: SV
authors.lastname: Tkacheva
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Iakovlev
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000276:immunology; D001792:Blood Platelets / Q000276:immunology; D004731:Endotoxins / Q000276:immunology; D004755:Enterobacteriaceae / Q000276:immunology; D004804:Eosinophils / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology; D006017:Glycolipids / Q000276:immunology; D019694:Hepatitis B, Chronic / Q000097:blood / Q000276:immunology*; D019698:Hepatitis C, Chronic / Q000097:blood / Q000276:immunology*; D006801:Humans; D007958:Leukocyte Count; D009504:Neutrophils / Q000276:immunology; D010976:Platelet Count
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D004731:Endotoxins; D006017:Glycolipids; C055264:Re-glycolipid; C044101:endotoxin, Escherichia coli