[Acute myelogenous leukemia associated with severe esophageal stricture after chemotherapy].
A 41-year-old woman with relapsed acute myelogenous leukemia was treated twice with idarubicin hydrochloride and cytarabine. She developed a 6-cm-long stricture in the lower esophagus 12 days after re-induction therapy. Although she had preceding candida infection, it is suspected that her stricture was caused by mucosal damage due to chemotherapeutic agents. This case suggests that the possibility of esophageal stricture should be considered in patients with swallowing disturbance after intensive chemotherapy.
Yata
Kenichiro
K
Division of Hematology, Department of Medicine, Kawasaki Medical School.
Yamada
Osamu
O
Iwato
Koji
K
Kyo
Taiichi
T
Otsuki
Takemi
T
Nakanishi
Hidekazu
H
Suetsugu
Yoshimasa
Y
Mikami
Makoto
M
Wada
Hideho
H
Yawata
Yoshihito
Y
Sugihara
Takashi
T
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D003561:Cytarabine / Q000008:administration & dosage / Q000009:adverse effects; D004940:Esophageal Stenosis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D015255:Idarubicin / Q000008:administration & dosage / Q000009:adverse effects; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*
D003561:Cytarabine; D015255:Idarubicin