title: Gastrointestinal side effects of NSAIDs - pharmacoeconomic implications.
abstract: NSAIDs are frequently used as analgesics. They have a high incidence of GI adverse effects that have both social and economic costs. These costs impose a considerable strain on healthcare resources. This review discusses the epidemiology and economic cost of these adverse GI events. It also highlights the variability in risk and the impact of newer drugs. Risk stratification and the subsequent guided use of NSAIDs is likely to limit the pharmacoeconomic implications.
authors.affiliation: Medicines Monitoring Unit, Ninewells Hospital, Dundee, UK. chris@memo.dundee.ac.uk
authors.forename: Christopher L
authors.initials: CL
authors.lastname: Sheen
authors.forename: Thomas M
authors.initials: TM
authors.lastname: MacDonald
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000191:economics*; D017281:Cost of Illness; D005767:Gastrointestinal Diseases / Q000139:chemically induced* / Q000191:economics* / Q000453:epidemiology; D006801:Humans
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal