Expression of SR-BI (Scavenger Receptor Class B Type I) in turtle (Chrysemys picta) tissues and other nonmammalian vertebrates.
In this study, the tissue distribution of the expression of an HDL-receptor (SR-BI; Scavenger Receptor Class B Type I) was investigated in the turtle using an antiserum to murine SR-BI. Several turtle tissues including liver, heart, small intestine, kidney, oviduct, ovary, and testis were shown to express an 82 kDa membrane protein. In addition, SR-BI expression in livers of other nonmammalian species such as the chicken, frog, goldfish, shark, and skate is also reported. Ovarian SR-BI expression varies seasonally in the turtle as do plasma levels of apoA-I and cholesterol ester. It is possible that changing levels of SR-BI, the receptor for apoA-I, is physiologically relevant to the demands of the turtle ovarian cycle and cholesterol distribution.
Duggan
Annemarie E
AE
Department of Biology, Boston University, Boston, Massachusetts 02215, USA. annemarie_duggan@hms.harvard.edu
Marie
Ronald Ste
RS
Callard
Ian P
IP
D000222:Adaptation, Physiological; D000818:Animals; D000906:Antibodies; D001001:Anura; D015153:Blotting, Western; D018955:CD36 Antigens / Q000096:biosynthesis*; D002645:Chickens; D002784:Cholesterol / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006054:Goldfish; D008565:Membrane Proteins; D051379:Mice; D010053:Ovary / Q000254:growth & development / Q000502:physiology*; D011971:Receptors, Immunologic; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; D051122:Scavenger Receptors, Class B; D012754:Sharks; D014018:Tissue Distribution; D014426:Turtles / Q000502:physiology*
D000906:Antibodies; D018955:CD36 Antigens; D008565:Membrane Proteins; D011971:Receptors, Immunologic; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; C454739:Scarb1 protein, mouse; D051122:Scavenger Receptors, Class B; D002784:Cholesterol