title: [Clinicopathological study of 52 cases of ameloblastoma of jaw].
abstract: OBJECTIVE
  To observe the relationship between the histologic types, tumor invasion, operation mode and recurrence of ameloblastoma.
  
  
  METHODS
  Using WHO classification (1992) for histological typing of odontogenic tumors, 52 cases of ameloblastoma were studied clinicopathologically.
  
  
  RESULTS
  The 8 pathological types are: follicle formation type, plexiform type, acanthoma type, basal cell type, granular cell type, desmoplastic ameloblastoma, kerato ameloblastoma and ameloblastoma accompanied by bone formation. Recurrence in the 8 above types following surgery were 5/11, 0/5, 7/15, 5/8, 0/3, 0/3, 2/3 and 1/4 respectively. Five cases recurred in 21 patients with tumor cells infiltrating into the connective tissue surrounding the tumors. 12 cases recurred in 16 patients with tumor cells infiltrating thru the capsule into surrounding soft tissue. The recurrence rate in patients who had their tumor enucleated or curetted was 56.5% (13/23). The recurrence rate in the tumors resected together with involved bone segment was 24.1% (7/29). Multiple recurrences occurred in 3 cases whose tumors were not well differentiated and had atypical cells.
  
  
  CONCLUSIONS
  Recurrence was more often seen in the follicular, acanthoma, basaloid, and keratoid types of ameloblastoma. When these tumors invade adjacent soft tissues, the recurrence rate is also higher. Recurrence is linked to conservative surgery and to tumors with low differentiation.
authors.affiliation: Departent of Pathology, Tianjin Cancer Hospital, Tianjin 300060.
authors.forename: S
authors.initials: S
authors.lastname: Liu
authors.forename: A
authors.initials: A
authors.lastname: Yan
authors.forename: A
authors.initials: A
authors.lastname: Feng
authors.forename: L
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000564:Ameloblastoma / Q000473:pathology*; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local