title: Health-related quality of life and treatment satisfaction in Dutch patients with type 2 diabetes.
abstract: OBJECTIVE
  To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction.
  
  
  METHODS
  For a sample of 1,348 type 2 diabetes patients, recruited by 29 general practitioners, we collected data regarding HRQOL. This study was performed as part of a larger European study (Cost of Diabetes in Europe - Type 2 [CODE-2]). We used a generic instrument (Euroqol 5D) to measure HRQOL. Treatment satisfaction was assessed using the Diabetes Treatment Satisfaction Questionnaire.
  
  
  RESULTS
  Patients without complications had an HRQOL (0.74) only slightly lower than similarly aged persons in the general population. Insulin therapy, obesity, and complications were associated with a lower HRQOL, independent of age and sex. Although higher fasting blood glucose and HbA1c levels were negatively associated with HRQOL, these factors were not significant after adjustment for other factors using multivariate analysis. Overall treatment satisfaction was very high. Younger patients, patients using insulin, and patients with higher HbA1c levels were less satisfied with the treatment than other patients.
  
  
  CONCLUSIONS
  Obesity and the presence of complications are important determinants of HRQOL in patients with type 2 diabetes.
authors.affiliation: Institute for Medical Technology Assessment (iMTA), Erasmus University, Rotterdam, the Netherlands. redekop@bmg.eur.nl
authors.forename: W Ken
authors.initials: WK
authors.lastname: Redekop
authors.forename: Marc A
authors.initials: MA
authors.lastname: Koopmanschap
authors.forename: Ronald P
authors.initials: RP
authors.lastname: Stolk
authors.forename: Guy E H M
authors.initials: GE
authors.lastname: Rutten
authors.forename: Bruce H R
authors.initials: BH
authors.lastname: Wolffenbuttel
authors.forename: Louis W
authors.initials: LW
authors.lastname: Niessen
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D001007:Anxiety; D003863:Depression; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology* / Q000523:psychology* / Q000628:therapy; D003927:Diet, Diabetic; D015444:Exercise; D005194:Family Practice; D005260:Female; D006304:Health Status; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D010146:Pain; D017060:Patient Satisfaction; D011788:Quality of Life; D012648:Self Care
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin