[Meta-analysis of risk factors on lung cancer in non-smoking Chinese female].
OBJECTIVE
To evaluate the risk factors of lung cancer in non-smoking Chinese women.


METHODS
The results of 7 case-control studies from 1990 to 1999 were analyzed by Meta-analysis method in this study. The cumulative cases and controls were 1 115 and 1 520, respectively. Der Simonian and Nan Laid model were applied to process data.


RESULTS
The pools OR values of family history of lung cancer, personal history of non-neoplastic lung disease, cooking oil fume pollution, coal pollution and exposure to environmental tobacco smoking (ETS) were 2.87, 2.79, 2.52, 1.42 and 1.64 respectively.


CONCLUSIONS
Family history of lung cancer and personal history of non-neoplastic lung disease might serve as the most important risk factors of female lung cancer in China. There appeared also significantly positive relationship between female lung cancer and the degree of cooking oil fume pollution or pollution of coal burning. The effect on lung cancer of exposure to ETS was uncertain in this study which calls for further investigation. Bias and confounding factors were also discussed in this study.
Zhang
Y
Y
Department of Epidemiology, The Affiliated Medical College of Zhejiang University, Hangzhou 310006, China.
Chen
K
K
Zhang
H
H
D016902:Air Pollution, Indoor; D016022:Case-Control Studies; D003296:Cooking; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects