The role of technetium-99m MAG3 renal imaging in the diagnosis of acute tubular necrosis of native kidneys.
The differential diagnosis for patients with acute renal failure of their native kidneys, as a result of primary intrarenal disease, includes acute tubular necrosis, glomerulonephritis, and interstitial nephritis. The role of MAG3 renography has not been studied in this setting. The authors describe four patients with acute renal failure in whom MAG3 renal imaging reliably identified acute tubular necrosis, as confirmed by follow-up kidney biopsies. In contrast to the poor parenchymal uptake observed in glomerulonephritis and interstitial nephritis, MAG3 shows a distinctive pattern in patients with acute tubular necrosis. For patients with acute renal failure, a renal scan can facilitate decision-making regarding the initiation of therapy.
Blaustein
Daniel A
DA
Department of Internal Medicine, Division of Nephrology, State University of New York, Health Science Center at Brooklyn, New York, USA.
Myint
Maung M
MM
Babu
Krishnan
K
Avram
Morrell M
MM
Chandramouli
Belur S
BS
D058186:Acute Kidney Injury / Q000000981:diagnostic imaging* / Q000209:etiology; D000368:Aged; D003937:Diagnosis, Differential; D005921:Glomerulonephritis / Q000000981:diagnostic imaging; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging*; D007683:Kidney Tubular Necrosis, Acute / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide
D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide