title: [Sudden death during anesthesia: human error, drug related or cardiac death?].
abstract: We carried out a retrospective analysis of 1500 forensic autopsies following sudden unexpected cardiac death. This analysis showed a group of 43 cases that could have been related to surgery and/or anaesthesia. Pathological examination revealed the existence of cardiac lesions in 40 cases: arrhythmogenic right ventricular cardiomyopathy (14 cases), coronary artery disease (9 cases), cardiomyopathy (8 cases), structural abnormalities of the His bundle (7 cases), mitral valve prolapse (1 case) and acute myocarditis (1 case). These disorders are compatible with a paroxysmal (rhythmic) phenomenon at the origin of the cardiac arrest. Identification of the cause of death in a patient who was presumed to be at low risk may provide major relief to the patient's family and the medical staff.
authors.affiliation: Service d'Anatomie et de Cytologie Pathologique, Hôpital L. Pradel, 69394, Lyon, France.
authors.forename: A
authors.initials: A
authors.lastname: Tabib
authors.forename: L
authors.initials: L
authors.lastname: Chalabreysse
authors.forename: C
authors.initials: C
authors.lastname: Barel
authors.forename: C
authors.initials: C
authors.lastname: Duracher
authors.forename: R
authors.initials: R
authors.lastname: Loire
authors.forename: D
authors.initials: D
authors.lastname: Malicier
authors.forename: A
authors.initials: A
authors.lastname: Miras
authors.forename: S
authors.initials: S
authors.lastname: Thilhet-Coartet
authors.forename: B
authors.initials: B
authors.lastname: Bui-Xuan
authors.forename: Q
authors.initials: Q
authors.lastname: Timour
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000758:Anesthesia / Q000009:adverse effects*; D000777:Anesthetics / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D003645:Death, Sudden / Q000209:etiology*; D016757:Death, Sudden, Cardiac / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008508:Medication Errors / Q000401:mortality*; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000777:Anesthetics