Ancient schwannoma arising in a lymph node: report of a case and review of the literature.
We report a case of an intranodal schwannoma in a 79-year-old woman. The patient underwent a left colectomy for a colonic adenocarcinoma, with regional lymph node dissection. Macroscopic examination of the specimen revealed a well-circumscribed 4 cm nodule located in the pericolic fat. Macroscopically, it was interpreted as a metastatic lymph node. Microscopically, the nodule was composed of a proliferation of bland spindle cells, was immunohistochemically positive for S100 protein, and negative for smooth muscle actin, desmin, and cytokeratin. The pathological findings led to the diagnosis of a very rare case of primary schwannoma of the lymph node.
Piana
S
S
Servizio di Anatomia ed Istologia Patologica, Ospedale Santa Maria Nuova, Reggio Emilia, Italy. piana.simonetta@Asmn.re.it
Gelli
M C
MC
Cavazza
A
A
Serra
L
L
Gardini
G
G
D000005:Abdomen; D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D003110:Colonic Neoplasms / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000737:chemistry / Q000473:pathology*; D009378:Neoplasms, Multiple Primary; D009442:Neurilemmoma / Q000737:chemistry / Q000473:pathology*
D014408:Biomarkers, Tumor