title: Paradoxical reaction to the treatment of tuberculosis uncovering previously silent meningeal disease.
abstract: The development of paradoxical clinical worsening following initiation of tuberculosis treatment may complicate the clinical course of both HIV-infected and uninfected patients. We report a severe manifestation of the so called paradoxical reaction to the treatment of tuberculosis that unmasked previously silent meningeal disease in a 34-year-old HIV-infected male patient.
authors.affiliation: Department of Clinical Immunology, Hospital Universitário Gaffrée e Guinle, Universidade do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. walter-eyer@unirio.br
authors.forename: Walter A
authors.initials: WA
authors.lastname: Eyer-Silva
authors.forename: Jorge Francisco C
authors.initials: JF
authors.lastname: Pinto
authors.forename: Juçara
authors.initials: J
authors.lastname: Arabe
authors.forename: Carlos Alberto
authors.initials: CA
authors.lastname: Morais-De-Sa
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects*; D000995:Antitubercular Agents / Q000009:adverse effects*; D004347:Drug Interactions; D006801:Humans; D008297:Male; D014390:Tuberculosis, Meningeal / Q000175:diagnosis* / Q000209:etiology
chemical_list: D019380:Anti-HIV Agents; D000995:Antitubercular Agents