title: Using a bidimensional t test to compare simultaneous activations in functional brain MRI.
abstract: The aim of functional brain magnetic resonance imaging studies is to determine which regions of the brain are related to a given specific task. Different methods can be used to extract the functional signal and there is currently no consensus for this operation. Measures based on correlation are only relevant for a single task. In this paper, we propose a method based on a multivariable Student's t test that permits the comparison of the results of successive activations. This technique allows a qualitative analysis of complex tasks, making possible to deal with both similar and different activated cortical areas.
authors.affiliation: Department of Radiology, Hôpital d'Instruction des Armées du Val de Grâce, 74 Bd Port Royal, F75230, Paris, France. sabbherv@mail.pf
authors.forename: P
authors.initials: P
authors.lastname: Sabbah
authors.forename: F
authors.initials: F
authors.lastname: Zana
authors.forename: C
authors.initials: C
authors.lastname: Nioche
authors.forename: Y S
authors.initials: YS
authors.lastname: Cordoliani
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015999:Multivariate Analysis