[Study on hepatitis C virus genotyping in some parts of China].
OBJECTIVE
To study the genotypes of hepatitis C virus in some parts of China.


METHODS
Twenty-seven sera of plasma donors from Guan county of Hebei province, Zhoukou district of Henan province, and 36 patients with chronic hepatitis C from Beijing and Qingdao cities were tested for HCV RNA by Amplicor PCR kit. Thirty-six of 38 HCV RNA positive sera were further genotyped, using INNO-LiP A HCV II kit.


RESULTS
The HCV RNA positive rates of plasma donors and patients with chronic hepatitis C were 48.15% (13/27) and 69.44% (25/36) respectively. Genotyping data from 13 plasma donors and 23 patients with chronic hepatitis C showed that 29 (80.55%) were 1b, 5 (13.89%) were genotype 2, and 2 (5.56%) remained untyped.


CONCLUSIONS
1b seemed to be the prevalent HCV genotype in some parts of China.
Zhuang
H
H
Department of Microbiology, School of Basic Medicine, Beijing University, Beijing 100083, China.
Tracy
L
L
Cui
Y
Y
D005838:Genotype; D016174:Hepacivirus / Q000145:classification* / Q000235:genetics; D019698:Hepatitis C, Chronic / Q000821:virology*; D006801:Humans; D012367:RNA, Viral / Q000097:blood
D012367:RNA, Viral