title: Polytetrafluoroethylene-covered stent and coronary artery aneurysms.
abstract: Angiographically detected coronary aneurysms (i.e., coronary segment greater then 1.5 times the normal artery) have an incidence of 0.3%-4.9% among patients undergoing coronary angiography and have been reported after an intervention procedure with a frequency of 2%-10%. The indication for treatment and the best modality still need to be defined. Some authors reported the successful treatment of coronary aneurysms with the polytetrafluoroethylene (PTFE)-covered stent implantation, supporting the role of this strategy. In our institution, from September 1997 to December 1999 eight PTFE-covered stents were implanted to treat seven coronary aneurysms in seven patients. All aneurysms were successfully treated by the PTFE-covered stent. In one case, there was the necessity of an additional PTFE stent to cover the aneurysm completely. In no case did the loss of stent occur. No in-hospital MACE occurred. At 35 +/- 8 (21-44) months, six patients were symptom-free. Angiographic follow-up was performed in all patients at 10 +/- 6 months. Restenosis occurred in one patient (14%) who had repeat percutaneous coronary interventions. This preliminary experience suggests that PTFE-covered stent may be useful in the treatment of coronary artery aneurysms.
authors.affiliation: Laboratory of Interventional Cardiology, Vita-Salute University School of Medicine, San Raffaele Hospital, Milan, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Briguori
authors.forename: Cristiano
authors.initials: C
authors.lastname: Sarais
authors.forename: Ginevra
authors.initials: G
authors.lastname: Sivieri
authors.forename: Takuro
authors.initials: T
authors.lastname: Takagi
authors.forename: Carlo
authors.initials: C
authors.lastname: Di Mario
authors.forename: Antonio
authors.initials: A
authors.lastname: Colombo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D020099:Coated Materials, Biocompatible; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011877:Radionuclide Imaging; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D020099:Coated Materials, Biocompatible; D011138:Polytetrafluoroethylene