Total synthesis of isoroquefortine C.
A short and efficient total synthesis of isoroquefortine C, the 3,12-(Z)-isomer of roquefortine C, from L-tryptophan methyl ester hydrochloride and 4(5)-(hydroxy)methylimidazole hydrochloride is described.
Schiavi
Bruno M
BM
Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, USA.
Richard
David J
DJ
Joullié
Madeleine M
MM
D004873:Ergolines / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings; D007211:Indoles; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry; D010879:Piperazines; D013055:Spectrophotometry, Infrared
D004873:Ergolines; D006576:Heterocyclic Compounds, 4 or More Rings; D007211:Indoles; D010879:Piperazines; C012536:roquefortine