title: Factors associated with delay in the diagnosis of oral cancer.
abstract: Early detection and treatment improve the prognosis for oral cancer. Delays from the onset of symptoms to clinical diagnosis are common. Our aim is to identify factors associated with this delay. Between 1995 and 1998, we interviewed 105 consecutive patients with histologically confirmed oral cancer in Greece. If 21 or more days elapsed from the time the patient noticed major symptoms to a definitive diagnosis, we called it a delay (52% of cases). We used logistic and linear regression to estimate odds ratios of delayed diagnosis and to identify correlates of length of delay, respectively. Former smokers had a 4.3 times greater risk of delayed diagnosis compared with current smokers (95% confidence interval: 1.1-17.1). The length of delay was greater among single patients, non-smokers, or those with stage IV tumors. Clinicians should be advised that delay in the diagnosis of oral cancer occurs frequently, even in individuals who do not smoke heavily.
authors.affiliation: Department of Oral Health Policy & Epidemiology, Harvard School of Dental Medicine, Boston, MA 02115, USA.
authors.forename: W
authors.initials: W
authors.lastname: Pitiphat
authors.forename: S R
authors.initials: SR
authors.lastname: Diehl
authors.forename: G
authors.initials: G
authors.lastname: Laskaris
authors.forename: V
authors.initials: V
authors.lastname: Cartsos
authors.forename: C W
authors.initials: CW
authors.lastname: Douglass
authors.forename: A I
authors.initials: AI
authors.lastname: Zavras
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking; D001835:Body Weight; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000235:genetics; D016022:Case-Control Studies; D016001:Confidence Intervals; D004651:Employment; D005260:Female; D006115:Greece; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D017533:Marital Status; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000235:genetics; D009367:Neoplasm Staging; D016017:Odds Ratio; D009909:Oral Health; D010610:Pharyngeal Neoplasms / Q000175:diagnosis / Q000235:genetics; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking; D018709:Statistics, Nonparametric; D013997:Time Factors