Urinary trypsin inhibitor levels in the urine of patients with haematological malignancies.
The urinary trypsin inhibitor (UTI) levels in the urine of patients with various haematological malignancies were determined, using automated latex agglutination immunoturbidimetry. The mean UTI levels in urine in acute non-lymphocytic leukaemia, myelodysplastic syndrome, non-Hodgkin's lymphoma, and multiple myeloma groups were significantly elevated, compared with the normal control group. It was found that the UTI level in urine changed from an elevated value to a normal value with haematological improvement by chemotherapy in a patient with myelodysplastic syndrome included in a previous study. These results suggest tha
Takubo
T
T
Clinical Hematology and Clinical Diagnostics, Graduate School of Medicine, Osaka City University, Japan. m3542254@med.osaka-cu.ac.jp
Kumura
T
T
Nakamae
H
H
Aoyama
Y
Y
Koh
K R
KR
Ohta
K
K
Yamane
T
T
Hino
M
M
Kanashima
H
H
Kamitani
T
T
Ohta
T
T
Kuwajima
S
S
Tatsumi
N
N
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology; D014408:Biomarkers, Tumor / Q000276:immunology / Q000652:urine*; D016022:Case-Control Studies; D019337:Hematologic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000652:urine; D006801:Humans; D007841:Latex Fixation Tests / Q000379:methods; D009391:Nephelometry and Turbidimetry / Q000379:methods; D014361:Trypsin Inhibitors / Q000187:drug effects / Q000276:immunology / Q000652:urine*
D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D014361:Trypsin Inhibitors