title: Asymmetric synthesis of 1-aryl-1,2-ethanediols from arylacetylenes by palladium-catalyzed asymmetric hydrosilylation as a key step.
abstract: Double hydrosilylation of arylacetylenes with trichlorosilane catalyzed first by platinum and second by a chiral monophosphine-palladium complex generated the corresponding 1,2-bis(silyl)-1-arylethanes, the oxidation of which with hydrogen peroxide gave 1-aryl-1,2-diols of high enantiomeric purity (94-98% ee) in high yields.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
authors.forename: Toyoshi
authors.initials: T
authors.lastname: Shimada
authors.forename: Kotaro
authors.initials: K
authors.lastname: Mukaide
authors.forename: Akihiro
authors.initials: A
authors.lastname: Shinohara
authors.forename: Jin Wook
authors.initials: JW
authors.lastname: Han
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi