title: [Methotrexate--mechanism of action and application].
abstract: The paper present modern views on turnover, mechanism of action and application of methotrexate. Contraindications and the most frequent side effects observed in certain number of patients treated with this drug are discussed.
authors.affiliation: Zespół Reumatologiczny Kliniki Pneumonologii i Alergologii Instytutu Medycyny Wewnetrznej AM w Łodzi.
authors.forename: B
authors.initials: B
authors.lastname: Dabkowska
authors.forename: J
authors.initials: J
authors.lastname: Dabkowski
mesh_terms: D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000494:pharmacology / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000494:pharmacology / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology / Q000627:therapeutic use; D008727:Methotrexate / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D018501:Antirheumatic Agents; D003879:Dermatologic Agents; D004791:Enzyme Inhibitors; D007166:Immunosuppressive Agents; D008727:Methotrexate