title: Ancient schwannoma arising in a lymph node: report of a case and review of the literature.
abstract: We report a case of an intranodal schwannoma in a 79-year-old woman. The patient underwent a left colectomy for a colonic adenocarcinoma, with regional lymph node dissection. Macroscopic examination of the specimen revealed a well-circumscribed 4 cm nodule located in the pericolic fat. Macroscopically, it was interpreted as a metastatic lymph node. Microscopically, the nodule was composed of a proliferation of bland spindle cells, was immunohistochemically positive for S100 protein, and negative for smooth muscle actin, desmin, and cytokeratin. The pathological findings led to the diagnosis of a very rare case of primary schwannoma of the lymph node.
authors.affiliation: Servizio di Anatomia ed Istologia Patologica, Ospedale Santa Maria Nuova, Reggio Emilia, Italy. piana.simonetta@Asmn.re.it
authors.forename: S
authors.initials: S
authors.lastname: Piana
authors.forename: M C
authors.initials: MC
authors.lastname: Gelli
authors.forename: A
authors.initials: A
authors.lastname: Cavazza
authors.forename: L
authors.initials: L
authors.lastname: Serra
authors.forename: G
authors.initials: G
authors.lastname: Gardini
mesh_terms: D000005:Abdomen; D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D003110:Colonic Neoplasms / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000737:chemistry / Q000473:pathology*; D009378:Neoplasms, Multiple Primary; D009442:Neurilemmoma / Q000737:chemistry / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor