title: Microvascular complications in cystic fibrosis-related diabetes mellitus: a case report.
abstract: CONTEXT, The prevalence of cystic fibrosis-related diabetes mellitus is increasing and is associated with increased survival from cystic fibrosis. CASE REPORT, This study describes a case of the premature onset of disabling and widespread microvascular complications resulting from cystic fibrosis-related diabetes mellitus. Previously asymptomatic retinopathy was diagnosed on recognition of diabetic nephropathy. CONCLUSIONS, The treatment of pulmonary exacerbations has become more complex due to the nephrotoxic potential of intravenous aminoglycoside drugs which are frequently used to control chronic Pseudomonas infection in cystic fibrosis.
authors.affiliation: Adult Cystic Fibrosis Unit, University of Queensland, The Prince Charles Hospital. Chermside, Queensland, Australia.
authors.forename: A I
authors.initials: AI
authors.lastname: Scott
authors.forename: B E
authors.initials: BE
authors.lastname: Clarke
authors.forename: H
authors.initials: H
authors.lastname: Healy
authors.forename: M
authors.initials: M
authors.lastname: D Emden
authors.forename: S C
authors.initials: SC
authors.lastname: Bell
mesh_terms: D000328:Adult; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D003550:Cystic Fibrosis / Q000503:physiopathology*; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003928:Diabetic Nephropathies / Q000175:diagnosis; D005260:Female; D006801:Humans; D007769:Lactams; D008833:Microcirculation / Q000503:physiopathology*; D018410:Pneumonia, Bacterial / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy; D051437:Renal Insufficiency / Q000097:blood / Q000175:diagnosis
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D007769:Lactams