[Mannose receptor].
The mannose receptor (MR) is a calcium-dependent C-type lectin that is expressed on some macrophages, immature dendritic cells, endothelial, and epithelial cells. The most important feature of MR is the capability to distinguish self from non-self molecules through the interaction of multiple CRDs. The purpose of the short review is to summarise the structural and functional properties of MR.
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Zakład Terapii Doświadczalnej Instytutu Immunologii i Terapii Doświadczalnej PAN, Wrocław.
D000818:Animals; D050260:Carbohydrate Metabolism; D006801:Humans; D007239:Infections / Q000276:immunology* / Q000378:metabolism; D037181:Lectins, C-Type; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins; D011956:Receptors, Cell Surface / Q000276:immunology / Q000378:metabolism*; D013329:Structure-Activity Relationship
D037181:Lectins, C-Type; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins; D011956:Receptors, Cell Surface