Treatment of alcohol withdrawal with gabapentin.
Gabapentin is an anticonvulsant agent, also effective in the treatment of mood disorders and anxiety disorders. Three cases of alcohol withdrawal treated with gabapentin are presented. All patients received gabapentin 400 mg tid for 3 days, 400 mg bid for 1 day, and finally 400 mg for 1 day. Withdrawal symptoms subsided and no adverse effects were observed. The possible effectiveness of gabapentin in the treatment of alcohol withdrawal warrants further investigation by systematic and well-designed studies.
Bozikas
Vasilis
V
First Department of Psychiatry, Aristotle University of Thessaloniki, Greece.
Petrikis
Petros
P
Gamvrula
Katerina
K
Savvidou
Ioanna
I
Karavatos
Athanasios
A
D000085:Acetates / Q000627:therapeutic use*; D000328:Adult; D000588:Amines; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D003509:Cyclohexanecarboxylic Acids; D000431:Ethanol / Q000009:adverse effects*; D000077206:Gabapentin; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000188:drug therapy / Q000209:etiology; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*; D005680:gamma-Aminobutyric Acid
D000085:Acetates; D000588:Amines; D014151:Anti-Anxiety Agents; D003509:Cyclohexanecarboxylic Acids; D000431:Ethanol; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin