Etiopathogenesis of inflammatory bowel disease: the importance of the pediatric perspective.
Inflammatory bowel disease (IBD) is now recognized as a common chronic disease affecting children and adolescents. This article will review recent advances made in the fields of genetics, epidemiology, gut ecology, and immunology regarding the etiopathogenesis of IBD, with particular emphasis on the contributions made by pediatric studies. Areas where further study of the pediatric age group would be beneficial will be highlighted.
Oliva-Hemker
Maria
M
Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Johns Hopkins University School of Medicine, Brady 320, 600 N. Wolfe St., Baltimore, MD 21287-2631, USA. moliva@jhmi.edu
Fiocchi
Claudio
C
D002648:Child; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology*