title: [A study on relationship between hypertension and polymorphism of ACE gene in male Yi people in Liangshan Yi autonomous prefecture, Sichuan].
abstract: OBJECTIVE
  To explore relationship between polymorphism of ACE gene and hypertension.
  
  
  METHODS
  A cross-sectional study was conducted and PCR technique was used to analyze gene polymorphism.
  
  
  RESULTS
  Genotypes DD, ID and II of ACE gene accounted for 13.0% and 9.7%, 50.9% and 48.4%, and 36.1% and 41.9%, respectively, in the normotensives and hypertensives. Frequencies of I and D alleles for ACE gene were 61.6% and 66.1%, and 38.4% and 33.9%, respectively, in the normotensives and hypertensives. There was no significant difference in distribution of II, ID and DD genotypes and I/D allele frequencies of ACE gene between the hypertensives and normotensives in male Yi people.
  
  
  CONCLUSIONS
  Association between polymorphism of ACE gene and hypertension was uncertain.
authors.affiliation: Department of Epidemiology, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100005.
authors.forename: G
authors.initials: G
authors.lastname: Shan
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: C
authors.initials: C
authors.lastname: Qiu
authors.forename: C
authors.initials: C
authors.lastname: Ren
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: P
authors.initials: P
authors.lastname: Wang
authors.forename: Z
authors.initials: Z
authors.lastname: Wu
authors.forename: S
authors.initials: S
authors.lastname: Liao
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Tong
authors.forename: K
authors.initials: K
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002681:China / Q000208:ethnology; D003430:Cross-Sectional Studies; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000201:enzymology* / Q000235:genetics; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D007703:Peptidyl-Dipeptidase A