[A case of Pneumocystis carinii pneumonia with pulmonary cysts and increased level of serum KL-6].
In August, 1999, a 46-year-old man with fever, cough, and dyspnea was admitted to a hospital. On the basis of the clinical and radiographic findings, bacterial pneumonia was suspected. Antibiotics were not effective, because of atypical lymphocytes in the peripheral blood and positive anti-human T-cell leukemia virus antibody, and he was transferred to our hospital. A chest radiograph and a CT scan revealed bilateral ground-glass opacities with huge multiple cysts. Intensive treatment of Pneumocystis carinii pneumonia associated with human T-cell leukemia was unsuccessful. Pneumocystis carinii was found in the bronchoalveolar lavage fluid. Human T-cell leukemia and Pneumocystis carinii pneumonia were diagnosed. In this case, numerous pulmonary cysts were progressing rapidly, the largest cyst being 8.7 cm in diameter, and the largest cyst in our experience either in clinical practice or in reading of the literature in Pneumocystis carinii pneumonia. The maximum serum KL-6 was markedly increased to 15,200 U/ml, which is the highest level reported for Pneumocystis carinii pneumonia.
Ominami
S
S
Department of Respiratory Disease, University of Occupational and Environmental Health, Kitakyushu.
Hayashi
T
T
Yoshii
C
C
Matsumoto
Y
Y
Itoh
T
T
Kawajiri
T
T
Imanaga
T
T
Kido
M
M
D000941:Antigens; D000951:Antigens, Neoplasm; D003560:Cysts / Q000150:complications*; D006023:Glycoproteins; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications; D008171:Lung Diseases / Q000150:complications*; D008297:Male; D008875:Middle Aged; D018396:Mucin-1; D009077:Mucins; D011020:Pneumonia, Pneumocystis / Q000097:blood / Q000150:complications*
D000941:Antigens; D000951:Antigens, Neoplasm; D006023:Glycoproteins; C060192:MUC1 protein, human; D018396:Mucin-1; D009077:Mucins