title: Continuous protein recovery from whey using liquid-solid circulating fluidized bed ion-exchange extraction.
abstract: A liquid-solid circulating fluidized bed (LSCFB) continuous ion-exchange extraction system has been investigated for total protein recovery from whey solutions under various operating conditions. The effectiveness of a dynamic seal was evaluated between the riser and the downcomer, and the best conditions for the establishment of this seal were established. Start-up studies indicated that the system is robust and stable. Under optimal conditions, a productivity of 8.2 g of total protein removed per hour per kilogram of resin was achieved with a protein removal efficiency of 78.4%. However, higher overall protein recovery of up to 90% was also achieved under other conditions, with lower protein concentration in the effluent and a lower overall productivity.
authors.affiliation: Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, ON, Canada N6A 5B9.
authors.forename: Qingdao
authors.initials: Q
authors.lastname: Lan
authors.forename: Amarjeet
authors.initials: A
authors.lastname: Bassi
authors.forename: Jing-Xu Jesse
authors.initials: JX
authors.lastname: Zhu
authors.forename: Argyrios
authors.initials: A
authors.lastname: Margaritis
mesh_terms: D019149:Bioreactors; D004867:Equipment Design; D008894:Milk Proteins / Q000302:isolation & purification* / Q000493:pharmacokinetics; D008956:Models, Chemical; D012212:Rheology; D012680:Sensitivity and Specificity; D000067816:Whey Proteins
chemical_list: D008894:Milk Proteins; D000067816:Whey Proteins