title: Effect of ingestion of honey on symptoms of rhinoconjunctivitis.
abstract: BACKGROUND
  Allergic rhinoconjunctivitis is a common disorder, affecting >20% of people of all socioeconomic strata. Despite this high prevalence, relatively few sufferers seek professional medical help, presumably because of a widespread reliance on complementary remedies.
  
  
  OBJECTIVE
  We investigated the widely held belief among allergy-sufferers that regular ingestion of honey ameliorates the symptoms of allergic rhinoconjunctivitis.
  
  
  METHODS
  The study was conducted at the University of Connecticut Health Center's Lowell P. Weicker General Clinical Research Center. Thirty-six participants who complained of allergic rhinoconjunctivitis were recruited. All recruits were scratch-tested at entry for common aeroallergens. The cohort was randomly assigned to one of three groups, with one receiving locally collected, unpasteurized, unfiltered honey, the second nationally collected, filtered, and pasteurized honey, and the third, corn syrup with synthetic honey flavoring. They were asked to consume one tablespoonful a day of the honey or substitute and to follow their usual standard care for the management of their symptoms. All participants were instructed to maintain a diary tracking 10 subjective allergy symptoms, and noting the days on which their symptoms were severe enough to require their usual antiallergy medication.
  
  
  RESULTS
  Neither honey group experienced relief from their symptoms in excess of that seen in the placebo group.
  
  
  CONCLUSIONS
  This study does not confirm the widely held belief that honey relieves the symptoms of allergic rhinoconjunctivitis.
authors.affiliation: Department of Pathology, UConn Health Center, Farmington 06030-3105, USA. rajan@neuron.uchc.edu
authors.forename: T V
authors.initials: TV
authors.lastname: Rajan
authors.forename: Howard
authors.initials: H
authors.lastname: Tennen
authors.forename: Richard L
authors.initials: RL
authors.lastname: Lindquist
authors.forename: Leonard
authors.initials: L
authors.lastname: Cohen
authors.forename: J
authors.initials: J
authors.lastname: Clive
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D003233:Conjunctivitis, Allergic / Q000628:therapy*; D004311:Double-Blind Method; D005260:Female; D006722:Honey; D006801:Humans; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000628:therapy*; D012882:Skin Tests; D016896:Treatment Outcome