title: Endocarditis Caused by Multiply Resistant Bacteroides fragilis: Case Report and Review.
abstract: A 78-year-old woman developed fatal endocarditis of her prosthetic aortic valve, caused by Bacteroides fragilis fragilis, and associated with ovarian carcinoma. The strain showed multiple antibiotic resistance, including resistance to beta-lactam agents and combinations with beta-lactamase inhibitors. Seventeen previously described cases of endocarditis caused by Bacteroides spp. have been found in the literature. The mean age of the 18 patients was 50.3 years, the gastro-intestinal tract was the most common site of associated disease, embolism occured in ten cases and eight patients died. Previous isolates showed the antibiotic susceptibility customarily associated with the B. fragilis group.
authors.affiliation: Service de Microbiologie, Hôpital Broussais, Paris.
authors.forename: Olivier
authors.initials: O
authors.lastname: Lortholary
authors.forename: Annie
authors.initials: A
authors.lastname: Buu-Hoï
authors.forename: Isabelle
authors.initials: I
authors.lastname: Podglajen
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Boucherie
authors.forename: Isabelle
authors.initials: I
authors.lastname: Pipien
authors.forename: Laurent
authors.initials: L
authors.lastname: Gutmann
authors.forename: Jacques
authors.initials: J
authors.lastname: Acar