Relationship between cadmium concentration in rice and renal dysfunction in individual subjects of the Jinzu River basin determined using a logistic regression analysis.
We investigated the association between the Cd concentration in rice and renal dysfunction in individuals living in the Cd-polluted Jinzu River basin, using a logistic regression analysis. In the cases of logistic regression analysis for people (1) who had either resided in the present hamlet since birth or who had moved there from a non-polluted area and for those (2) who had resided in the present hamlet since birth, except for glucosuria in males, all partial correlation coefficients between the Cd concentration in rice and occurrence of abnormal urinary findings were statistically significant in both sexes. The allowable level of Cd concentration in rice was calculated by substituting the abnormality rates of urinary findings of the controls in the 40-49, 50-59 and 60-69 year age groups into the logistic regression formula for people (3). The value for subjects aged 50 years was 0.13 and 0.17 ppm for males and females, respectively, with regard to proteinuria and 0.15 and 0.10 ppm for males and females, respectively, with regard to proteinuria+glucosuria.
Watanabe
Yoshitaka
Y
Department of Occupational and Environmental Medicine, Graduate School of Medicine (A2), Chiba University, 1-8-1 Inohana, Chuohku, 260-8670, Chiba, Japan.
Kobayashi
Etsuko
E
Okubo
Yasushi
Y
Suwazono
Yasushi
Y
Kido
Teruhiko
T
Nogawa
Koji
K
D000328:Adult; D000367:Age Factors; D000368:Aged; D002105:Cadmium Poisoning / Q000453:epidemiology* / Q000652:urine; D005260:Female; D005506:Food Contamination; D006029:Glycosuria / Q000453:epidemiology; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007674:Kidney Diseases / Q000453:epidemiology* / Q000652:urine; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012275:Oryza / Q000506:poisoning*; D011507:Proteinuria / Q000453:epidemiology; D012737:Sex Factors; D014874:Water Pollutants, Chemical / Q000506:poisoning*
D014874:Water Pollutants, Chemical