title: Surface-active phospholipid in total hip arthroplasty.
abstract: This is the first report of surface-active phospholipid as the boundary lubricant in total hip arthroplasty. Aspirate and rinsings from the bearing surfaces of 25 revision operations and one primary surgery were analyzed from 3 weeks to 26 years postoperatively. All samples contained substantial amounts of surface-active phospholipids ranging from 14 to 4186 microg. These findings indicate that synoviocytes continue producing the lubricant in significant quantities after arthroplasty surgery independent of the type of joint replacement and its fixation. Surface-active phospholipid was found on all bearing surfaces analyzed including polyethylene, stainless steel, chrome cobalt, alumina, zirconia, and titanium.
authors.affiliation: Wrightington Hospital for Joint Disease, Appley Bridge, Wigan, United Kingdom.
authors.forename: Bodo
authors.initials: B
authors.lastname: Purbach
authors.forename: Brian A
authors.initials: BA
authors.lastname: Hills
authors.forename: B Michael
authors.initials: BM
authors.lastname: Wroblewski
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D006622:Hip Prosthesis; D006801:Humans; D010743:Phospholipids / Q000032:analysis*; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000378:metabolism; D012086:Reoperation; D013582:Synovial Fluid / Q000737:chemistry
chemical_list: D010743:Phospholipids