[Treatment of the ocular burn with hormone].
OBJECTIVE
To explore new ways of the management of ocular burn with the use of hormones (human growth hormone and corticosteroid).


METHODS
Twenty-one patients (30 eyes) with ocular burn were enrolled in the study. Nine cases (12 eyes) were treated with routine methods, while in 12 cases (18 eyes) corticosteroid and recombinant human growth hormone (rhGH) were used. The corticosteroid was applied immediately postburn both systemically and topically and continued for 2-4 weeks. But the rhGH was applied after 1 week postburn and continued for 2 weeks. The results in the above two groups were compared.


RESULTS
Compared with those in control group, all the 18 eyes in the 12 patients with ocular burn were saved and cured with the treatments of hormones. There was significantly less incidence of corneal ulceration and perforation and better visual recovery in those treated with the hormones.


CONCLUSIONS
Combined application of corticosteroid and rhGH might be beneficial to the management of patients with ocular burn.
Han
C
C
Department of Burns, Second Affiliated Hospital, Medical School, Zhe Jiang University, Hangzhou 310009, Zhe Jiang Province, P. R. China.
Yao
Y
Y
Yu
C
C
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D002056:Burns / Q000188:drug therapy*; D002057:Burns, Chemical / Q000188:drug therapy*; D005131:Eye Injuries / Q000188:drug therapy*; D005260:Female; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D019382:Human Growth Hormone