ER dislocation: Cdc48p/p97 gets into the AAAct.
Misfolded or unassembled proteins present in the lumen of the endoplasmic reticulum are exported to the cytosol and degraded. Recent studies have implicated a complex containing the AAA ATPase Cdc48p/p97 in the export process.
Lord
J Michael
JM
Department of Biological Sciences, University of Warwick, CV4 7AL, Coventry, UK.
Ceriotti
Aldo
A
Roberts
Lynne M
LM
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001693:Biological Transport, Active; D018797:Cell Cycle Proteins / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D000074405:Valosin Containing Protein
D018797:Cell Cycle Proteins; D011506:Proteins; D000251:Adenosine Triphosphatases; D000074405:Valosin Containing Protein