Biliary surgery in sickle cell disease: the Jamaican experience.
Of 62 patients with homozygous sickle cell disease subjected to open cholecystectomy for symptomatic gallstones over a 12-year period at the University Hospital of the West Indies, 25 were males and 37 were females. Of these, 27 were paediatric patients aged 18 years or less, and 35 were adults. Preoperative transfusion was selectively administered. All cases presented with right upper quadrant pain and 15 of 62 with obstructive jaundice. Mucocoele of the gallbladder, empyema of the gallbladder and common bile duct stones were detected in 2, 2, and 23 patients, respectively. Exploration of the common bile duct was necessary in 31 cases and a T-tube sited in 15 cases. Twelve of the 62 patients developed acute chest syndrome post operatively (20%). There were 2 deaths, both occurring in patients who had developed acute chest syndrome; in a 34 year old and a 10 year old patient. Common bile duct related morbidity was proportionately more common in paediatric patients than adults, represented by ductal dilation (48% vs 37%), ductal calculi (44% vs 31%) and retained stones (7% vs 3%).
Duncan
N D
ND
Department of Surgery, Radiology, Anaesthesia and Intensive Care, University Hospital of the West Indies, Jamaica.
Smith
A I
AI
McDonald
A H
AH
Mitchell
D I G
DI
D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications / Q000601:surgery*; D002648:Child; D002763:Cholecystectomy; D002769:Cholelithiasis / Q000209:etiology / Q000601:surgery*; D005260:Female; D006801:Humans; D007563:Jamaica; D008297:Male; D012189:Retrospective Studies