title: Calcium hydroxide root canal dressing. Histopathological evaluation of periapical repair at different time periods.
abstract: The objective of this study was to evaluate periapical and apical repair using calcium hydroxide root canal dressings for different lengths of times in teeth with induced chronic periapical lesions. A total of 61 root canals of maxillary and mandibular premolars from 4 dogs were used. After mechanical preparation of the root canals using the crown-down technique, and 5.25% NaOCl as irrigating solution, the apical foramen was enlarged in all cases. A calcium hydroxide root canal dressing was applied. The control group did not receive a root canal dressing. The animals were killed at 7, 15 or 30 days. After histological preparation, serial sections were stained with hematoxylin-eosin and Mallory's trichrome. The best histopathological results occurred at 15 and 30 days, and the worst results occurred at 7 days and in the control group.
authors.affiliation: Department of Endodontics, School of Dentistry of Araraquara, UNESP, Araraquara, SP, Brazil. secendo@foar.unesp.br
authors.forename: Mario Roberto
authors.initials: MR
authors.lastname: Leonardo
authors.forename: Frank Ferreira
authors.initials: FF
authors.lastname: Silveira
authors.forename: Léa Assed Bezerra da
authors.initials: LA
authors.lastname: Silva
authors.forename: Mário
authors.initials: M
authors.lastname: Tanomaru Filho
authors.forename: Lidia Sabbag
authors.initials: LS
authors.lastname: Utrilla
mesh_terms: D016301:Alveolar Bone Loss / Q000188:drug therapy; D000818:Animals; D002126:Calcium Hydroxide / Q000008:administration & dosage*; D016009:Chi-Square Distribution; D002908:Chronic Disease; D003739:Dental Cementum / Q000187:drug effects; D004285:Dogs; D010485:Periapical Periodontitis / Q000188:drug therapy*; D010486:Periapical Tissue / Q000187:drug effects*; D010513:Periodontal Ligament / Q000187:drug effects; D012388:Root Canal Irrigants / Q000008:administration & dosage*; D013997:Time Factors; D019227:Tooth Apex / Q000187:drug effects*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D012388:Root Canal Irrigants; D002126:Calcium Hydroxide