Vibrational circular dichroism of gramicidin D in vesicles and micelles.
The vibrational circular dichroism (VCD) and absorption spectra of gramicidin D in three model membranes (dioctadecyldimethylammonium chloride vesicles, dimyristoyl-phosphatidylcholine vesicles, and sodium dodecyl sulfate micelles) are presented. The absorption and VCD spectra suggest that the stable gramicidin D conformation in the model membranes is different from those in organic solvents. The presence of cations does not change the membrane-bound conformation of gramicidin D.
Zhao
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C
Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, USA.
Polavarapu
P L
PL
D002942:Circular Dichroism; D017666:Deuterium Oxide; D004134:Dimyristoylphosphatidylcholine; D006096:Gramicidin / Q000737:chemistry*; D008081:Liposomes; D008823:Micelles; D000644:Quaternary Ammonium Compounds; D012967:Sodium Dodecyl Sulfate; D013053:Spectrophotometry; D014732:Vibration
D008081:Liposomes; D008823:Micelles; D000644:Quaternary Ammonium Compounds; D006096:Gramicidin; C015831:dimethyldioctadecylammonium; D012967:Sodium Dodecyl Sulfate; D017666:Deuterium Oxide; D004134:Dimyristoylphosphatidylcholine