Structured treatment interruptions in HIV/AIDS therapy.
Structured treatment interruption (STI) has been investigated for three distinct clinical scenarios: during acute infection with the goal of immune reconstitution and auto immunization; during chronic infection, to decrease the amount and toxicity of antiretroviral drugs; and during virologic failure to restore response to subsequent antiretroviral therapy. The potential costs and benefits of STI should be determined.
Lisziewicz
Julianna
J
Research Institute for Genetic and Human Therapy, IRCCS Policlinico S. Matteo, P. le Golgi, 2 - 27100, Pavia, Italy. rightpv@tin.it
Lori
Franco
F
D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000191:economics / Q000379:methods*; D018791:CD4 Lymphocyte Count; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D006801:Humans; D010349:Patient Compliance; D012306:Risk; D019562:Viral Load
D019380:Anti-HIV Agents