title: Nurse-led weaning from mechanical ventilation: where's the evidence?
abstract: BACKGROUND
  Several authors have suggested clinical protocols as a means of shortening ventilation time and the important role of the nurse in reducing ventilation time has also been highlighted. Despite the many references in the literature to reducing weaning times using clinical protocols, it is not clear whether nurse-led weaning strategies hasten weaning from mechanical ventilation compared with physician-led care.
  
  
  OBJECTIVE
  to systematically review the published literature to answer the question: Does nurse-led weaning from mechanical ventilation reduce duration of ventilation compared with doctor-led care?
  
  
  METHODS
  MEDLINE, CINHAL, EMBASE, Cochrane Library, Best Evidence, hand search, expert opinion, controlled trials register.
  
  
  METHODS
  randomized controlled trials (RCTs) and cohort studies where nurses or respiratory therapists lead the weaning from mechanical ventilation; duration of ventilation must be stated.
  
  
  METHODS
  performed by the author, who extracted data on statistical significance of the difference in duration of ventilation between control and trial groups, complication rates (such as reintubation) and mortality.
  
  
  RESULTS
  statistical synthesis was not attempted but narrative synthesis was performed.
  
  
  RESULTS
  only 1 randomized controlled trial and 2 cohort studies were found where nurses or respiratory therapists led weaning using a protocol. Two studies showed reduction in ventilation time without additional complications; the third study had the weakest evidence, because it was retrospective, and showed no difference between control and treatment groups.
  
  
  CONCLUSIONS
  There is limited evidence suggesting that nurse-led weaning may reduce ventilation time; however, it is not clear whether it was the nurse-led aspect or the clinical protocol that produced the effect.
authors.affiliation: The Florence Nightingale School of Nursing & Midwifery, Kings College London, & ITU, Royal Free Hospital, UK.
authors.forename: A M
authors.initials: AM
authors.lastname: Price
mesh_terms: D002985:Clinical Protocols / Q000592:standards; D015331:Cohort Studies; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D013997:Time Factors; D015300:Ventilator Weaning / Q000379:methods / Q000451:nursing*