title: Addressing the challenge of intergroup studies in oncology: the EORTC experience. European Organisation for Research and Treatment of Cancer.
abstract: Intergroup studies are conducted by more than one clinical research group. There are several difficulties that hamper in practice the possibility of conducting such trials, as all interested parties will have to address unusual and complex issues. These are mainly related to differences in size, interests, motivations and means among different research organisations. The EORTC recognises the importance to promote intergroup collaboration providing to all interested groups the necessary expertise and organisational support to conduct intergroup studies. The role of the EORTC evolved from the spontaneous organisations of intergroup trials to the definition of a basic set of principles and criteria that groups have to fulfil to participate in intergroup trials. Recently, a specific EORTC Intergroup Office started its activity devoted to solve the issues related to the intergroup co-operation. This office will have an increasing role to promote and help in conducting intergroup studies.
authors.affiliation: EORTC Data Center, Avenue E. Mounier 83, 1200, Brussels, Belgium. azu@eortc.be
authors.forename: A
authors.initials: A
authors.lastname: Zurlo
authors.forename: P
authors.initials: P
authors.lastname: Therasse
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods*; D005060:Europe; D006801:Humans; D007390:International Agencies / Q000458:organization & administration*; D007391:International Cooperation; D008495:Medical Oncology / Q000458:organization & administration*; D015337:Multicenter Studies as Topic / Q000379:methods*