Left ventricular dysfunction in children with fulminant enterovirus 71 infection: an evaluation of the clinical course.
We describe 2 children with typical hand, foot, and mouth disease due to enterovirus 71 infection, 1 of whom died. Both cases were complicated by acute fulminant shock syndrome; the patients had remarkable acute left ventricular dysfunction. The clinical experience indicates that the rapid death associated with fulminant enterovirus rhombencephalitis is the result of rapid cardiogenic shock rather than neurogenic pulmonary edema.
Huang
Fang-Liang
FL
Department of Pediatrics, Taichung Veterans General Hospital, Taichung, National Yang-Ming University, Taipei, Taiwan, Republic of China.
Jan
Sheng-Ling
SL
Chen
Po-Yen
PY
Chi
Ching-Shiang
CS
Wang
Teh-Ming
TM
Fu
Yun-Ching
YC
Tsai
Chi-Ren
CR
Chang
Yan
Y
D002675:Child, Preschool; D004770:Enterovirus / Q000472:pathogenicity; D004769:Enterovirus Infections / Q000150:complications* / Q000401:mortality; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012770:Shock, Cardiogenic / Q000209:etiology; D018487:Ventricular Dysfunction, Left / Q000209:etiology* / Q000401:mortality