Triterpenes from Mimusops elengi.
Pentacyclic triterpenes (1) and (2) have been isolated from Mimusops elengi and assigned structures 3beta,6beta,19alpha,23-tetrahydroxy-urs-12-ene and 1beta-hydroxy-3beta-hexanoyllup-20 (29)-ene-23, 28-dioic acid, respectively, on the basis of spectroscopic studies including 2D-NMR. The compound 1 showed moderate inhibiting activity against beta-glucuronidase enzyme
Jahan
N
N
International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Pakistan.
Malik
A
A
Mustafa
G
G
Ahmad
Z
Z
Ahmad
S
S
Anis
E
E
Malik
S
S
Shujaat
S
S
Afza
N
N
Atta-Ur-Rahman
D000818:Animals; D002417:Cattle; D002855:Chromatography, Thin Layer; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005966:Glucuronidase / Q000037:antagonists & inhibitors*; D020128:Inhibitory Concentration 50; D008099:Liver; D013058:Mass Spectrometry; D008519:Medicine, Traditional; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010154:Pakistan; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C447719:1beta-hydroxy-3beta-hexanoyllup-20 (29)-ene-23, 28-dioic acid; C447702:3beta,6beta,19alpha,23-tetrahydroxy-urs-12-ene; D004791:Enzyme Inhibitors; D014315:Triterpenes; D005966:Glucuronidase