title: [Pulmonary involvement, pleural effusion, and electrocardiographic abnormality in hypereosinophilic syndrome].
abstract: A 47-year-old man was admitted to our hospital with complaints of cough and shortness of breath. Chest radiography showed infiltration of the right lung and left pleural effusion, the eosinophil count increased notably in the peripheral blood, sputum, and pleural effusion. Transbronchial lung biopsy revealed the invasion of eosinophils like eosinophilic pneumonia. Heart failure easily developed in this patient after the intravenous infusion. Myocardial involvement was suspected, and hypereosinophilic syndrome was diagnosed. After prednisolone was administered, the peripheral blood eosinophil count normalized rapidly, and subsequently, the pleural effusion and infiltration shadows in the lung disappeared.
authors.affiliation: Department of Internal Medicine, National Minami-Okayama Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Kawai
authors.forename: S
authors.initials: S
authors.lastname: Kawahara
authors.forename: A
authors.initials: A
authors.lastname: Tada
authors.forename: A
authors.initials: A
authors.lastname: Kuyama
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: G
authors.initials: G
authors.lastname: Kimura
authors.forename: C
authors.initials: C
authors.lastname: Okada
authors.forename: R
authors.initials: R
authors.lastname: Soda
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Okamoto
authors.forename: M
authors.initials: M
authors.lastname: Nakajima
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004562:Electrocardiography; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D011657:Pulmonary Eosinophilia / Q000150:complications* / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone