Preterm infants born at less than 31 weeks' gestation have improved growth in cycled light compared with continuous near darkness.
OBJECTIVE
Our purpose was to evaluate the benefits of cycled light (CL) versus near darkness (ND) on health in preterm infants born at <31 weeks' gestational age.


METHODS
Randomized, interventional study comparing infants receiving (1) CL from birth, (2) CL at 32 weeks' postconceptional age (PCA), and (3) CL at 36 weeks' PCA in transition for discharge home. Statistical significance was assessed with segmented mixed general linear models, analysis of covariance, general estimating equations, chi(2), and Fisher's exact procedure.


RESULTS
Infants receiving CL at birth and 32 weeks' PCA gained weight faster than infants not receiving CL until 36 weeks' PCA. There were no differences among the groups in length of hospitalization stay or number of ventilator days, but the power was low for these variables.


CONCLUSIONS
These findings suggest that CL has significant weight gain benefits over ND, and there are no short-term advantages of ND over cycled light for health in preterm infants.
Brandon
Debra H
DH
Duke University School of Nursing, Duke Perinatal Research Institute, Durham, North Carolina 27710, USA.
Holditch-Davis
Diane
D
Belyea
Michael
M
D001835:Body Weight; D002940:Circadian Rhythm; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development*; D007363:Intensive Care Units, Neonatal; D007902:Length of Stay; D008027:Light; D012121:Respiration, Artificial; D012178:Retinopathy of Prematurity; D013997:Time Factors