title: Malnutrition interferes with the unique lymphadenopathy induced in Lewis rats by metallic tin.
abstract: Metallic tin powder injected into Lewis rats caused marked enlargement of draining lymph nodes with prominent hyperplasia of plasma cells. A low level of dietary protein (8%) or deficiency of choline interfered with the cellular proliferation and reduced the size of the nodes by nearly one-third compared to a normal protein diet (20%). A high level of protein in the diet (50%) did not augment the effect of metallic tin powder beyond that achieved by a level usually considered adequate (20%).
authors.affiliation: Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.
authors.forename: Seymour
authors.initials: S
authors.lastname: Levine
authors.forename: Arthur
authors.initials: A
authors.lastname: Saltzman
mesh_terms: D000818:Animals; D002796:Choline Deficiency / Q000473:pathology; D004032:Diet; D005260:Female; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000139:chemically induced* / Q000473:pathology*; D009748:Nutrition Disorders / Q000473:pathology*; D009929:Organ Size / Q000187:drug effects; D010950:Plasma Cells / Q000473:pathology; D051381:Rats; D011917:Rats, Inbred Lew; D014001:Tin
chemical_list: D014001:Tin