title: [Clinical aspects, etiology, pathogenesis, diagnosis and therapy of aseptic bone necrosis--a current analysis of the literature].
abstract: With continuous proliferation of magnetic resonance imaging early detection of avascular bone necrosis becomes progressively important for treatment of early disease stages. The last decades intensified research on the field of ostoenecrosis has lead to different etiopathogenetic models and to new treatment options. Thereby long term results of known operative interventions are now available. Those can be used as a standard of treatment, new innovative techniques (e.g. mosaic arthoplasty or chondrocyte transplantation) might also be added. The goal of this paper is to give a comprehensive review about Osteonecrosis, Osteochondrosis and Osteochondritis dissecans. Respectively the latest literature results we are able to subordinate these to one unit with mechanical stress as a significant etiological factor in common. Knowledge derived form single literature marks are perhaps comprehended to general picture.
authors.affiliation: Schulthess-Klinik Zürich.
authors.forename: R
authors.initials: R
authors.lastname: Dotti
authors.forename: D M
authors.initials: DM
authors.lastname: Müller
authors.forename: A
authors.initials: A
authors.lastname: Benini
mesh_terms: D001842:Bone and Bones / Q000473:pathology; D003937:Diagnosis, Differential; D005271:Femur Head Necrosis / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D006801:Humans; D010007:Osteochondritis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D010008:Osteochondritis Dissecans / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D010020:Osteonecrosis / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery