Dental disease indices and caries related oral microflora in children with phenylketonuria.
The purpose of this study was to investigate the dental caries, plaque and gingivitis indices and caries related oral flora in children with classic phenylketonuria. Forty-one children at The Great Ormond Street Hospital for Children and controls were included in the study. The main findings were: No significant difference in the decayed, missing and filled surfaces of the primary and permanent teeth between the phenylketonuria children and the controls. A significantly greater mean plaque score for the control children compared with the phenylketonuria children (p < 0.01) for the permanent teeth only. A significantly greater number of white opacities in the permanent teeth of the phenylketonuria group compared with the control group (p < 0.02). No significant differences in the caries related microflora.
Lucas
V S
VS
Department of Oral Medicine, Eastman Dental Institute for Oral Health Care Sciences, University of London, 256 Gray's Inn Road, London WC1X 8LD.
Contreras
A
A
Loukissa
M
M
Roberts
G J
GJ
D002176:Candida albicans / Q000254:growth & development; D002327:Cariostatic Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000150:complications / Q000382:microbiology*; D003743:Dental Enamel / Q000002:abnormalities; D003773:Dental Plaque / Q000150:complications / Q000382:microbiology; D003774:Dental Plaque Index; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D005891:Gingivitis / Q000150:complications; D006801:Humans; D007778:Lactobacillus / Q000254:growth & development; D008297:Male; D010512:Periodontal Index; D010661:Phenylketonurias / Q000150:complications*; D012463:Saliva / Q000382:microbiology; D013223:Statistics as Topic; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000254:growth & development*; D014076:Tooth Diseases / Q000150:complications*; D014094:Tooth, Deciduous / Q000473:pathology
D002327:Cariostatic Agents; D005459:Fluorides