title: [The effectiveness of cyclosporin A in the treatment of autoimmune hemolytic anemia and Evans syndrome].
abstract: OBJECTIVE
  To test the therapeutic effectiveness of cyclosporin A (CsA) in combination with corticosteroid in the treatment of autoimmune hemolytic anemia(AIHA) and Evans syndrome.
  
  
  METHODS
  Forty-four cases of AIHA and Evans syndrome were treated with CsA in combination with a conventional regimen (prednisone + danazol) (18 cases) or conventional regimen alone(26 cases).
  
  
  RESULTS
  The complete response rate of CsA group (88.9%) was higher than that of conventional regimen group (57.7%) (P < 0.05), and the relapse rate was lower (3.3% vs 70%) (P < 0.01).
  
  
  CONCLUSIONS
  CsA in combination with conventional regimen can improve the complete response rate and reduce relapse of AIHA and Evans syndrome.
authors.affiliation: Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China.
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.forename: Z
authors.initials: Z
authors.lastname: Shao
authors.forename: L
authors.initials: L
authors.lastname: Jing
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000188:drug therapy*; D016572:Cyclosporine / Q000627:therapeutic use*; D003613:Danazol / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D016572:Cyclosporine; D003613:Danazol; D011241:Prednisone