title: Left ventricular dysfunction in children with fulminant enterovirus 71 infection: an evaluation of the clinical course.
abstract: We describe 2 children with typical hand, foot, and mouth disease due to enterovirus 71 infection, 1 of whom died. Both cases were complicated by acute fulminant shock syndrome; the patients had remarkable acute left ventricular dysfunction. The clinical experience indicates that the rapid death associated with fulminant enterovirus rhombencephalitis is the result of rapid cardiogenic shock rather than neurogenic pulmonary edema.
authors.affiliation: Department of Pediatrics, Taichung Veterans General Hospital, Taichung, National Yang-Ming University, Taipei, Taiwan, Republic of China.
authors.forename: Fang-Liang
authors.initials: FL
authors.lastname: Huang
authors.forename: Sheng-Ling
authors.initials: SL
authors.lastname: Jan
authors.forename: Po-Yen
authors.initials: PY
authors.lastname: Chen
authors.forename: Ching-Shiang
authors.initials: CS
authors.lastname: Chi
authors.forename: Teh-Ming
authors.initials: TM
authors.lastname: Wang
authors.forename: Yun-Ching
authors.initials: YC
authors.lastname: Fu
authors.forename: Chi-Ren
authors.initials: CR
authors.lastname: Tsai
authors.forename: Yan
authors.initials: Y
authors.lastname: Chang
mesh_terms: D002675:Child, Preschool; D004770:Enterovirus / Q000472:pathogenicity; D004769:Enterovirus Infections / Q000150:complications* / Q000401:mortality; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012770:Shock, Cardiogenic / Q000209:etiology; D018487:Ventricular Dysfunction, Left / Q000209:etiology* / Q000401:mortality