title: [Acute experimental pancreatitis in the opossum. The role of prior truncular vagotomy on the inflammatory response].
abstract: BACKGROUND
  Acute pancreatitis (AP) is a common cause of admission to the emergency room. Its etiopathogeny is poorly understood. The pancreatic inflammatory response in this process is unclear. The influence of the autonomic nervous system is a controversial issue.
  
  
  OBJECTIVE
  To demonstrate the effects of truncular vagotomy on AP due to duodenal distention in the South American opossum. PLACE OF APPLICATION: Department of experimental surgery (Churruca-Visca Hospital) INEUCI (Neuroscience Institute, CONICET, UBA).
  
  
  METHODS
  Male and female South American opossum divided into: a control group (7 animals); group A: truncular vagotomy and pyloroplasty seven days after the onset of AP (7 animals). Group B: truncular vagotomy and pyloroplasty 30 days after provoking AP (7 animals). Group C: truncular vagotomy and pyloroplasty 45 days after the onset of AP (7 animals).
  
  
  METHODS
  Acute pancreatitis was caused by duodenal distention of the second portion by inserting a Foley catheter through a gastrostomy.
  
  
  CONCLUSIONS
  The method of provoking AP is original. The influence of autonomous nervous system is being underestimated in most of the literature available.
authors.affiliation: Sección Cirugía Experimental, Servicio de Cirugía General, Complejo Hospitalario Churruca-Visca.
authors.forename: H A
authors.initials: HA
authors.lastname: García
authors.forename: O M
authors.initials: OM
authors.lastname: Tiscornia
authors.forename: O
authors.initials: O
authors.lastname: Iodice
authors.forename: P
authors.initials: P
authors.lastname: Cal
authors.forename: F J
authors.initials: FJ
authors.lastname: Gasali
authors.forename: A
authors.initials: A
authors.lastname: Maschietto
authors.forename: F
authors.initials: F
authors.lastname: Sapin
authors.forename: G
authors.initials: G
authors.lastname: Eufemio
authors.forename: S
authors.initials: S
authors.lastname: Sutera
authors.forename: L
authors.initials: L
authors.lastname: Uchiumi
authors.forename: J
authors.initials: J
authors.lastname: Affani
mesh_terms: D000208:Acute Disease; D000818:Animals; D004386:Duodenum / Q000503:physiopathology; D005260:Female; D008297:Male; D009893:Opossums; D010195:Pancreatitis / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D011446:Prospective Studies; D011708:Pylorus / Q000601:surgery; D013997:Time Factors; D015167:Vagotomy, Truncal / Q000379:methods*