title: [A case of sarcoidosis involving multiple organs that showed significant improvement as the serum KL-6 level fell after steroid therapy].
abstract: Pulmonary sarcoidosis was diagnosed by transbronchial lung biopsy in a 27-year old man admitted to our hospital in September 1996. In October 1999, bilateral parenchymal findings on chest radiography and the results of pulmonary function tests had significantly deteriorated compared with those of three years before. Since skin, heart, liver, and spleen lesions were also detected, this patient was treated with corticosteroids. The lung parenchymal lesions and the pulmonary function as well as the abnormal findings in other organs showed significantly improvement along with a decrease of the KL-6 level after steroid therapy.
authors.affiliation: Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashiku, Fukuoka 812-8582, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Kuwano
authors.forename: T
authors.initials: T
authors.lastname: Matsuba
authors.forename: M
authors.initials: M
authors.lastname: Kawasaki
authors.forename: K
authors.initials: K
authors.lastname: Yoshida
authors.forename: N
authors.initials: N
authors.lastname: Hagimoto
authors.forename: N
authors.initials: N
authors.lastname: Hara
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D000941:Antigens / Q000097:blood*; D000951:Antigens, Neoplasm; D015415:Biomarkers / Q000097:blood; D009202:Cardiomyopathies / Q000473:pathology; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D008107:Liver Diseases / Q000473:pathology; D008297:Male; D018396:Mucin-1; D009077:Mucins; D011239:Prednisolone / Q000008:administration & dosage*; D017565:Sarcoidosis, Pulmonary / Q000188:drug therapy* / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology; D013158:Splenic Diseases / Q000473:pathology
chemical_list: D000893:Anti-Inflammatory Agents; D000941:Antigens; D000951:Antigens, Neoplasm; D015415:Biomarkers; D006023:Glycoproteins; C060192:MUC1 protein, human; D018396:Mucin-1; D009077:Mucins; D011239:Prednisolone