[Observations on prostate histology in 50 young and middle aged men. Its implication on clinical pathological diagnosis].
OBJECTIVE
To investigate the morphology and the relationship between the prostate and the adjacent structures in order to clarify its significance in histopathological diagnosis.


METHODS
By means of light microscopy, and in part by electron microscopy and immunohistochemistry, the histology of 50 normal prostates were observed.


RESULTS
The parenchymal component can be divided into four zones, i.e. peripheral zone, central zone, transitional zone and periurethral gland region, each characterized by its own anatomical and histological features.


CONCLUSIONS
This 4 zone division of prostate has more clinical significance than the traditional division of the prostate. A good knowledge of the normal structure of the prostate has great practical significance in pathologic diagnosis.
Ma
J
J
Department of Pathology, Friendship Hospital, Beijing 100050.
Huang
S
S
Zhang
C
C
Shao
Q
Q
D000135:Acid Phosphatase / Q000032:analysis; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D008854:Microscopy, Electron; D010338:Pathology, Clinical / Q000379:methods; D011467:Prostate / Q000033:anatomy & histology* / Q000737:chemistry / Q000648:ultrastructure; D017430:Prostate-Specific Antigen / Q000032:analysis
C121278:CK-34 beta E12; D007633:Keratins; D000135:Acid Phosphatase; D017430:Prostate-Specific Antigen