title: [Adaptive thermoregulatory reactions of the rabbit fetus at the end of the intrauterine development].
abstract: The data of permanent simultaneous registration of electrocardiogram, rectal & brown adipose tissue temperatures of the rabbit foetus have been obtained in chronic experiments. The haemodynamic shift in intensity of maternal-placental and foeto-placental blood flow (by female trental injection) led to a decrease in the foetus rectal temperature (0.33 +/- 0.09 degree C in intact foetus and 0.58 +/- 0.27 degree C in retarded foetus, p < 0.05). Both foetuses reacted by rectal temperature decrease (0.65 +/- 0.28 & 0.68 +/- 0.31 degree C, respectively) during immobilisation (by foetus arduan injection). Thus in both series of experimental cooling of foetus, brown fat activation was similar in intact foetus (approximately 53%), but did not change in growth retardation foetus--as a result of its tissue functional immaturity, probably.
authors.affiliation: D. O. Ott Institute of Obstetrics and Gynaecology, Russian Acad. Med. Sci, I. P. Pavlov Institute of Physiology, St. Petersburg, Russia.
authors.forename: L A
authors.initials: LA
authors.lastname: Nazarova
authors.forename: O P
authors.initials: OP
authors.lastname: Petrova
authors.forename: N N
authors.initials: NN
authors.lastname: Konstantinova
mesh_terms: D000222:Adaptation, Physiological; D002001:Adipose Tissue, Brown / Q000502:physiology; D000818:Animals; D001831:Body Temperature; D001833:Body Temperature Regulation; D004562:Electrocardiography; D005260:Female; D005333:Fetus / Q000502:physiology*; D006439:Hemodynamics; D006706:Homeostasis; D009043:Motor Activity; D010431:Pentoxifylline / Q000494:pharmacology; D021041:Placental Circulation / Q000187:drug effects; D011247:Pregnancy; D011817:Rabbits; D014599:Uterus / Q000098:blood supply
chemical_list: D010431:Pentoxifylline