title: [Rheumatoid purpura in adults and parvovirus B19 infection: fortuitous association or parvovirus B19-induced vasculitis?].
abstract: BACKGROUND
  Henoch-Schoenlein purpura has been reported to be associated with parvovirus B19 infection, particularly in children and rarely in adults. We report the case of a 42-year-old patient presenting with this association.
  
  
  METHODS
  A 42-year-old patient was admitted to our medical center because of lower limb purpura. Henoch-Schoenlein purpura diagnosis was confirmed on histological findings (kidney biopsy) and concomitantly parvovirus B19 infection was proved by serological test (IgM+). Association of Henoch-Schoenlein purpura and parvovirus B19 infection has already been described. However, none of the reported studies demonstrated clearly the link between these two diseases. With regard to this observation, we wonder about the systematic use of the parvovirus B19 serological test in patients presenting first Henoch-Schoenlein purpura. Indeed, parvovirus B19-induced vasculitis is habitually controlled with intravenous immunoglobulins.
  
  
  CONCLUSIONS
  A prospective study should explore the link between Henoch-Schoenlein purpura and primary parvovirus B19 infection. Moreover, we should evaluate intravenous immunoglobulins' efficacy in Henoch-Schoenlein purpura associated with active parvovirus B19 infection in order to improve the prognosis of this disease.
authors.affiliation: Service de médecine interne, hôpital Claude-Huriez, CHRU, rue Polonovski, 59037 Lille, France.
authors.forename: T
authors.initials: T
authors.lastname: Quéméneur
authors.forename: M
authors.initials: M
authors.lastname: Lambert
authors.forename: A L
authors.initials: AL
authors.lastname: Fauchais
authors.forename: V
authors.initials: V
authors.lastname: Queyrel
authors.forename: U
authors.initials: U
authors.lastname: Michon-Pasturel
authors.forename: E
authors.initials: E
authors.lastname: Hachulla
authors.forename: P Y
authors.initials: PY
authors.lastname: Hatron
authors.forename: B
authors.initials: B
authors.lastname: Devulder
mesh_terms: D000328:Adult; D001706:Biopsy; D006801:Humans; D011695:IgA Vasculitis / Q000209:etiology / Q000473:pathology / Q000821:virology*; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007668:Kidney / Q000473:pathology; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications* / Q000175:diagnosis; D016732:Parvovirus B19, Human / Q000276:immunology / Q000472:pathogenicity*; D012698:Serologic Tests
chemical_list: D016756:Immunoglobulins, Intravenous