A tense time for the nuclear envelope.
When many cells divide, the nuclear envelope poses a problem: the spindle microtubules can't access the chromosomes. Two recent papers in Cell describe how the spindle solves this problem by literally pulling open the nucleus at the beginning of mitosis.
Aitchison
John D
JD
Institute for Systems Biology, 1441 North 34th Street, Seattle, WA, USA.
Rout
Michael P
MP
D000818:Animals; D006801:Humans; D008870:Microtubules / Q000502:physiology*; D008938:Mitosis; D009685:Nuclear Envelope / Q000502:physiology*; D009687:Nuclear Proteins / Q000502:physiology; D010766:Phosphorylation; D017510:Protein Folding
D009687:Nuclear Proteins