title: Doppler myocardial imaging in the assessment of regional myocardial function in longitudinal direction pre- and post-PTCA.
abstract: OBJECTIVE
  Doppler myocardial imaging is potentially a sensitive tool to assess regional myocardial velocities pre- and post-percutaneous transluminal coronary angioplasty (PTCA) as a marker of contractility to evaluate short- to medium-term information on functional myocardial recovery following the release of ischaemia.
  
  
  METHODS
  Thirty patients with single vessel disease were studied to assess regional myocardial peak systolic velocity, systolic velocity time integral and mitral valve plane excursion in longitudinal direction one day pre-, one day post- and 3 months post-PTCA. The patients were assigned to group A with coronary stenoses >70% and group B with stenoses < 70%.
  
  
  RESULTS
  In group A pre-PTCA the ischaemic segments showed a significantly lower peak systolic velocity and velocity time integral compared with the values one day after PTCA (5.8 +/- 1.4 vs 7.7 +/- 1.4cm.s(-1); 1.06 +/- 0.22 vs 1.23 +/-0.28cm;P< 0.03). In contrast, mitral valve plane excursion in this group remained unchanged after PTCA for both the ischaemic and non-ischaemic left ventricular wall. In group B no changes of these parameters and no differences in mitral valve plane excursion of the ischaemic and the non-ischaemic left ventricular wall could be seen.
  
  
  CONCLUSIONS
  With Doppler myocardial imaging it was possible to quantify a number of indices which changed due to the successful release of ischaemia.
authors.affiliation: Linköping Heart Centre, University Hospital Linköping, Sweden. J.Strotmann@gmx.net
authors.forename: J M
authors.initials: JM
authors.lastname: Strotmann
authors.forename: A
authors.initials: A
authors.lastname: Richter
authors.forename: T
authors.initials: T
authors.lastname: Kukulski
authors.forename: J U
authors.initials: JU
authors.lastname: Voigt
authors.forename: S G
authors.initials: SG
authors.lastname: Fransson
authors.forename: B
authors.initials: B
authors.lastname: Wranne
authors.forename: L
authors.initials: L
authors.lastname: Hatle
authors.forename: G R
authors.initials: GR
authors.lastname: Sutherland
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D018619:Echocardiography, Doppler, Pulsed; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000628:therapy; D011446:Prospective Studies