title: Vibrational circular dichroism of gramicidin D in vesicles and micelles.
abstract: The vibrational circular dichroism (VCD) and absorption spectra of gramicidin D in three model membranes (dioctadecyldimethylammonium chloride vesicles, dimyristoyl-phosphatidylcholine vesicles, and sodium dodecyl sulfate micelles) are presented. The absorption and VCD spectra suggest that the stable gramicidin D conformation in the model membranes is different from those in organic solvents. The presence of cations does not change the membrane-bound conformation of gramicidin D.
authors.affiliation: Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, USA.
authors.forename: C
authors.initials: C
authors.lastname: Zhao
authors.forename: P L
authors.initials: PL
authors.lastname: Polavarapu
mesh_terms: D002942:Circular Dichroism; D017666:Deuterium Oxide; D004134:Dimyristoylphosphatidylcholine; D006096:Gramicidin / Q000737:chemistry*; D008081:Liposomes; D008823:Micelles; D000644:Quaternary Ammonium Compounds; D012967:Sodium Dodecyl Sulfate; D013053:Spectrophotometry; D014732:Vibration
chemical_list: D008081:Liposomes; D008823:Micelles; D000644:Quaternary Ammonium Compounds; D006096:Gramicidin; C015831:dimethyldioctadecylammonium; D012967:Sodium Dodecyl Sulfate; D017666:Deuterium Oxide; D004134:Dimyristoylphosphatidylcholine