title: Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies.
authors.affiliation: School of Biological & Chemical Science, Medicinal Chemistry Group, The University of Newcastle, Callaghan, NSW 2308, Australia. amcclusk@mail.newcastle.edu.au
authors.forename: Adam
authors.initials: A
authors.lastname: McCluskey
authors.forename: Alistair T R
authors.initials: AT
authors.lastname: Sim
authors.forename: Jennette A
authors.initials: JA
authors.lastname: Sakoff
mesh_terms: D000475:Alkenes / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D002193:Cantharidin / Q000737:chemistry / Q000627:therapeutic use; D018360:Crystallography, X-Ray; D016572:Cyclosporine / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D052998:Microcystins; D008958:Models, Molecular; D019319:Okadaic Acid / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D010456:Peptides, Cyclic / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D010749:Phosphoprotein Phosphatases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D011090:Polyenes; D011714:Pyrans; D011753:Pyrones; D013141:Spiro Compounds; D013329:Structure-Activity Relationship
chemical_list: D000475:Alkenes; D000903:Antibiotics, Antineoplastic; D000935:Antifungal Agents; D004791:Enzyme Inhibitors; D052998:Microcystins; D010456:Peptides, Cyclic; D011090:Polyenes; D011714:Pyrans; D011753:Pyrones; D013141:Spiro Compounds; C053079:tautomycin; D019319:Okadaic Acid; D016572:Cyclosporine; C049865:cyanoginosin-LA; D010749:Phosphoprotein Phosphatases; D002193:Cantharidin; C040313:fostriecin