title: Feeding deterrents from Dictamnus dasycarpus Turcz against two stored-product insects.
abstract: The screening for insecticidal principles from several Chinese medicinal herbs showed that the root bark of Dictamnus dasycarpus possessed significant feeding deterrence against two stored-product insects (Tribolium castaneum and Sitophilus zeamais). From the methanol extract, two feeding deterrents were isolated by bioassay-guided fractionation. The compounds were identified as fraxinellone and dictamnine from their spectroscopic data. Fraxinellone was demonstrated to possess feeding deterrent activity against adults and larvae of T. castaneum as well as S. zeamais adults with EC50 values of 36.4, 29.1, and 71.2 ppm, respectively. Dictamnine was shown to have feeding deterrent activity against adults and larvae of T. castaneum as well as S. zeamais adults with EC50 values of 57.6, 47.9, and 91.7 ppm, respectively.
authors.affiliation: Department of Biological Sciences, National University of Singapore, Block S2, 14 Science Drive 4, Singapore 117543.
authors.forename: Zhi Long
authors.initials: ZL
authors.lastname: Liu
authors.forename: Yuan Jian
authors.initials: YJ
authors.lastname: Xu
authors.forename: Jien
authors.initials: J
authors.lastname: Wu
authors.forename: Swee Hock
authors.initials: SH
authors.lastname: Goh
authors.forename: Shuit Hung
authors.initials: SH
authors.lastname: Ho
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D001572:Benzofurans / Q000302:isolation & purification / Q000494:pharmacology; D005591:Chemical Fractionation; D004435:Eating / Q000187:drug effects; D005506:Food Contamination / Q000517:prevention & control*; D007313:Insecta / Q000254:growth & development*; D007814:Larva / Q000254:growth & development; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D011804:Quinolines; D014231:Tribolium / Q000254:growth & development*
chemical_list: D000470:Alkaloids; D001572:Benzofurans; D010936:Plant Extracts; D011804:Quinolines; C075391:fraxinellone; C026398:dictamnine