Long-term results of surgical resection of lung metastases.
Between 1990 and 2000, 56 consecutive patients underwent lung resection for removal of metastatic disease. Mortality, disease-free interval, and overall survival were studied. Only patients with a complete follow-up were included and data were collected conform the protocol of the International Registry of Lung Metastases. The primary tumour in our series was an epithelial tumour in 25 patients (45%), sarcoma in 15 (27%), germ cell tumours in 11 (19%) and melanoma in 5. Operative mortality was 1.4% (1 out of 73 procedures). Germ cell tumours had the best survival (76% at 5 years), and melanoma the worst (0% at 5 years). Multivariate analysis showed that survival for patients who underwent 2 or more metastasectomies was surprisingly good with a 5-year survival rate of 46%. Survival was not related to disease-free interval, multiple lung metastases, or pneumonectomy. It is in accordance with some reports that a short disease-free interval, numerous lung metastases, or recurrence after the first metastasectomy should not preclude patients from operation.
Hendriks
J M
JM
Department of Thoracic and Vascular Surgery, Antwerp University Hospital, Edegem, Belgium. j.hendriks@planetinternet.be
Romijn
S
S
Van Putte
B
B
Eyskens
E
E
Vermorken
J B
JB
Van Marck
E
E
Van Schil
P E
PE
D000293:Adolescent; D000328:Adult; D003110:Colonic Neoplasms / Q000473:pathology; D005260:Female; D018237:Germinoma / Q000556:secondary / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D012509:Sarcoma / Q000601:surgery; D016019:Survival Analysis; D016896:Treatment Outcome