title: Separation of tanshinones from Salvia miltiorrhiza bunge by multidimensional counter-current chromatography.
abstract: Analytical and preparative high-speed counter-current chromatography (HSCCC) was successfully used for the isolation and purification of tanshinones from the roots of Salvia miltiorrhiza Bunge. Using multidimensional HSCCC, four major components including tanshinone IIA (16 mg), tanshinone I (10 mg), dihydrotanshinone I (7 mg) and cryptotanshinone (11 mg) were isolated each at high purity of over 95%.
authors.affiliation: Beijing Institute of New Technology Application, PR China.
authors.forename: Guilian
authors.initials: G
authors.lastname: Tian
authors.forename: Tianyou
authors.initials: T
authors.lastname: Zhang
authors.forename: Yabin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Ito
mesh_terms: D045784:Abietanes; D002851:Chromatography, High Pressure Liquid; D003377:Countercurrent Distribution / Q000379:methods*; D010616:Phenanthrenes / Q000302:isolation & purification*; D027544:Salvia / Q000737:chemistry*
chemical_list: D045784:Abietanes; D010616:Phenanthrenes; C021751:tanshinone