title: Hyalinizing clear cell carcinoma of minor salivary gland: case report.
abstract: Hyalinizing clear cell carcinoma is a low-grade neoplasm of the minor salivary gland composed exclusively of epithelial cells and not myoepithelial cells. It predominantly affects the oral cavity of adult females. It is microscopically characterized by hyalinizing stroma and clear cells, which are typically positive for cytokeratin markers and negative for S 100 and smooth muscle actin (SMA). Cystic degeneration can also be present. Pathologists should be aware of this new entity so as not to misdiagnose otherwise. To our knowledge, this is the first case report of its kind from Malaysia.
authors.affiliation: Department of Pathology, Hospital Universiti Sains Malaysia (HUSM), Kubang Kerian, Kelantan, Malaysia. madhavan@kb.usm.my
authors.forename: Madhavan
authors.initials: M
authors.lastname: Manoharan
authors.forename: Nor Hayati
authors.initials: NH
authors.lastname: Othman
authors.forename: Abdul Rani
authors.initials: AR
authors.lastname: Samsudin
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology*; D000328:Adult; D005260:Female; D006801:Humans; D008296:Malaysia; D009060:Mouth Floor / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000473:pathology*