title: A simple and efficient chemoselective method for the catalytic deprotection of acetals and ketals using bismuth triflate.
abstract: Bismuth triflate is a highly efficient catalyst (0.1-1 mol %) for the deprotection of acetals and ketals. The procedure is very facile and selective for acetals derived from ketones and conjugated aldehydes. tert-Butyldimethylsilyl ethers are stable to the reaction conditions. The highly catalytic nature of bismuth triflate and the use of a relatively nontoxic solvent system (THF/H(2)O) make this procedure particularly attractive for large-scale synthesis.
authors.affiliation: Department of Chemistry, Illinois Wesleyan University, Bloomington, Illinois 61701, USA.
authors.forename: Marc D
authors.initials: MD
authors.lastname: Carrigan
authors.forename: Dusan
authors.initials: D
authors.lastname: Sarapa
authors.forename: Russell C
authors.initials: RC
authors.lastname: Smith
authors.forename: Laura C
authors.initials: LC
authors.lastname: Wieland
authors.forename: Ram S
authors.initials: RS
authors.lastname: Mohan