Diagnostics of main coronary artery stenoses and occlusions: multiplane transoesophageal Doppler echocardiographic assessment.
OBJECTIVE
The possibility of using multiplane transoesophageal echocardiography (TEE) and quantitative coronary angiography (QCA) in the diagnostics of stenotic atherosclerosis of the main coronary arteries in a comparative aspect were studied in 94 patients with coronary artery disease (men, mean age 52 +/- 7 years). Coronary arteries stenoses were calculated with Doppler echocardiography using a modified continuity equation: stenosis (%)=100 x(1-prestenotic VTI(d)/stenotic VTI(d)) where prestenotic VTI(d), (cm)=diastolic velocity integral in the prestenotic zone, and stenotic VTI(d), (cm)=in the trans-stenotic zone.


RESULTS
High sensitivity and specificity of TEE in the diagnostics of stenotic and occlusive atherosclerosis of coronary arteries were revealed. They measured 88% and 98% for the left main coronary artery (LMCA), 97% and 67% for the left descending artery (LDA), 95% and 92% for the circumflex artery (CX), 83% and 97% for the right coronary artery (RCA), respectively. A high correlation was found between the results of TEE and QCA in the diagnostics of coronary stenoses which were made for the LMCA (r=0.82P <0.001), LDA (r=0.84, P<0.001), CX (r=0.85,P <0.001), and RCA (r=0.84, P<0.001). We developed Doppler echocardiography criteria for haemodynamically significant stenoses of coronary arteries (>50%) according to a peak diastolic velocity of the coronary blood flow, calculated as 1.4m.s(-1)for the LMCA, 0.9m.s(-1)for the LDA, and 1.1m.s(-1)for the CX. We determined Doppler echocardiography criteria of coronary arteries occlusions such as a 'break' of colour mapping, absence of Doppler spectrum and retrograde blood flow during late diastole.


CONCLUSIONS
Transoesophageal Doppler evaluation of coronary blood flow with application of a modified continuity equation is an accurate, non-invasive method of coronary arteries stenoses diagnostics.
Vrublevsky
A V
AV
Cardiology Research Institute, Tomsk, Russian Academy of Medical Sciences, Siberian Branch, Russia. alexvr@mail.tomsknet.ru
Boshchenko
A A
AA
Karpov
R S
RS
D001783:Blood Flow Velocity; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D003326:Coronary Circulation; D015150:Echocardiography, Doppler; D017548:Echocardiography, Transesophageal; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity