Paradoxical reaction to the treatment of tuberculosis uncovering previously silent meningeal disease.
The development of paradoxical clinical worsening following initiation of tuberculosis treatment may complicate the clinical course of both HIV-infected and uninfected patients. We report a severe manifestation of the so called paradoxical reaction to the treatment of tuberculosis that unmasked previously silent meningeal disease in a 34-year-old HIV-infected male patient.
Eyer-Silva
Walter A
WA
Department of Clinical Immunology, Hospital Universitário Gaffrée e Guinle, Universidade do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. walter-eyer@unirio.br
Pinto
Jorge Francisco C
JF
Arabe
Juçara
J
Morais-De-Sa
Carlos Alberto
CA
D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects*; D000995:Antitubercular Agents / Q000009:adverse effects*; D004347:Drug Interactions; D006801:Humans; D008297:Male; D014390:Tuberculosis, Meningeal / Q000175:diagnosis* / Q000209:etiology
D019380:Anti-HIV Agents; D000995:Antitubercular Agents