title: [Allergic alteration of leukocytes in patients with drug intolerance].
abstract: Increased sensitivity to benzylpenicillin, ampicillin, claforan, cefzol, novocain and lidocaine was determined by means of the leukocyte allergic alteration (LAA) test in 599 patients with intolerance reactions to these preparations in their medical history. In most of these patients the test results exceeded 30% and reached 98%, their average values exceeding those in the control group no subjects with no drug intolerance. The LAA test ensured a high level (83%) of the detection of drug intolerance.
authors.affiliation: Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Giunter
authors.forename: E B
authors.initials: EB
authors.lastname: Stepanova
authors.forename: V V
authors.initials: VV
authors.lastname: Sveranovskaia
authors.forename: V B
authors.initials: VB
authors.lastname: Gervazieva
mesh_terms: D048429:Cell Size; D004342:Drug Hypersensitivity / Q000097:blood / Q000175:diagnosis* / Q000276:immunology*; D005456:Fluorescent Dyes; D006801:Humans; D007118:Immunoassay; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology* / Q000473:pathology; D013194:Staining and Labeling
chemical_list: D005456:Fluorescent Dyes