title: Isoflavone content of the soy based supplements.
abstract: A large number of soy isoflavone products with indications of possible health effects are available on the market. Fifteen different soy based products were analyzed using high performance liquid chromatography (HPLC) with coulometric electrode array detector to determine the total amount of isoflavones in aglycones after the hydrolysis and identify the different forms of the isoflavone conjugates. The aim of the study was to evaluate how well the isoflavone content data supplied by the producers correspond to our analysis results. Only one product contained isoflavones measured in aglycones the same amount as was the value given by the producer. The total amount of the isoflavones in aglycones ranged from 0.121 to 201 mg/g. Measured amounts of isoflavones in aglycones after the hydrolysis were in general lower than the values in the product labels. Product data were often confusing and the concrete amount of isoflavones was difficult to find out.
authors.affiliation: Department of Clinical Chemistry, Folkhälsan Research Center, University of Helsinki, PO Box 63, Fin-00014 Helsinki, Finland. tarja.nurmi@uku.fi
authors.forename: T
authors.initials: T
authors.lastname: Nurmi
authors.forename: W
authors.initials: W
authors.lastname: Mazur
authors.forename: S
authors.initials: S
authors.lastname: Heinonen
authors.forename: J
authors.initials: J
authors.lastname: Kokkonen
authors.forename: H
authors.initials: H
authors.lastname: Adlercreutz
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods / Q000706:statistics & numerical data; D019587:Dietary Supplements / Q000032:analysis*; D004341:Drug Evaluation; D007529:Isoflavones / Q000032:analysis*; D013025:Glycine max / Q000737:chemistry*
chemical_list: D007529:Isoflavones