title: [Aspects of colchicine therapy. 1: Pharmacology, toxicology, classic indications].
abstract: Colchicine has been traditionally used for the treatment of gout. Many observations discuss the prophylactic and/or therapeutic action of colchicine upon a whole range of other diseases. The first part of the overview deals with the pharmacology, and toxicology and the classical indications.
authors.affiliation: Zentrum für Innere Medizin, Universität Giessen, Kerckhoff Klinik-Rheumatologie, Bad Nauheim. Uwe.Lange@kerckhoff.med.uni-giessen.de
authors.forename: Uwe
authors.initials: U
authors.lastname: Lange
authors.forename: Christian
authors.initials: C
authors.lastname: Schumann
authors.forename: Klaus L
authors.initials: KL
authors.lastname: Schmidt
mesh_terms: D003078:Colchicine / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D010505:Familial Mediterranean Fever / Q000188:drug therapy; D006073:Gout / Q000188:drug therapy*; D006074:Gout Suppressants / Q000493:pharmacokinetics / Q000627:therapeutic use* / Q000633:toxicity; D006801:Humans; D051437:Renal Insufficiency / Q000188:drug therapy
chemical_list: D006074:Gout Suppressants; D003078:Colchicine