title: Fungal flora and ochratoxin a production in grapes and musts from france.
abstract: Eleven samples of grapes and musts used in red table wines were investigated for the occurrence of potential ochratoxin A (OTA)-producing molds. From these samples, 59 filamentous fungi and 2 yeasts were isolated. Among the 30 genera isolated, Deuteromycetes were the most frequent (70%) followed by Ascomycetes (10%). Six of the eleven grapes samples were contaminated by potentially ochratoxinogenic strains (Penicillium chrysogenum and Aspergillus carbonarius). When cultivated in vitro on solid complex media, the 14 strains of A. carbonarius produced OTA. No other species produced OTA under the same conditions. Among must samples, eight of eleven were found to be contaminated by OTA (concentrations from <10 to 461 ng/L). There is a strong correlation between the presence of ochratoxin-producing strains on grapes and OTA in musts. These findings should be connected with the OTA contamination of human blood in these areas and in France.
authors.affiliation: Groupe pour l'Etude du Devenir des Xénobiotiques dans l'Environnement (GEDEXE), UFR de Pharmacie, Université Joseph Fourier, BP 138, 38243 Meylan Cedex, France.
authors.forename: Lucile
authors.initials: L
authors.lastname: Sage
authors.forename: Serge
authors.initials: S
authors.lastname: Krivobok
authors.forename: Emilie
authors.initials: E
authors.lastname: Delbos
authors.forename: Françoise
authors.initials: F
authors.lastname: Seigle-Murandi
authors.forename: Edmond E
authors.initials: EE
authors.lastname: Creppy
mesh_terms: D005511:Food Handling; D005602:France; D005638:Fruit / Q000382:microbiology*; D005658:Fungi / Q000145:classification* / Q000302:isolation & purification / Q000378:metabolism; D009183:Mycotoxins / Q000096:biosynthesis; D009793:Ochratoxins / Q000096:biosynthesis*
chemical_list: D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A