title: Functional changes in temporal lobe activity during transient global amnesia.
abstract: The integrity of temporal lobe activity during and after recovery from transient global amnesia (TGA) was assessed in a case study using functional MRI. TGA was associated with scene-encoding deficits in a temporolimbic circuit that recovered over time. Frontoparietal areas recruited during the amnesic state may signify a compensatory reliance on visuospatial or working memory strategies. Reduction of extrastriate cortex responses over repeated testing sessions possibly indicates intact visual priming in TGA.
authors.affiliation: Center for Cognitive Neuroscience, Duke University, Durham, NC 27708-0999, USA. klabar@duke.edu
authors.forename: Kevin S
authors.initials: KS
authors.lastname: LaBar
authors.forename: Darren R
authors.initials: DR
authors.lastname: Gitelman
authors.forename: Todd B
authors.initials: TB
authors.lastname: Parrish
authors.forename: M Marsel
authors.initials: MM
authors.lastname: Mesulam
mesh_terms: D000328:Adult; D020236:Amnesia, Transient Global / Q000175:diagnosis* / Q000503:physiopathology; D001921:Brain / Q000502:physiology / Q000503:physiopathology; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D020127:Recovery of Function / Q000502:physiology