Cyclopamine as a potential therapeutic agent for treatment of tumors related to hedgehog pathway mutations.
Miller
Stanley J
SJ
Johns Hopkins University, Baltimore, Maryland, USA.
Yu
Thomas C
TC
D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D053823:Hedgehog Proteins; D006801:Humans; D008517:Phytotherapy; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000235:genetics; D015534:Trans-Activators / Q000235:genetics; D014703:Veratrum; D014704:Veratrum Alkaloids / Q000494:pharmacology / Q000627:therapeutic use*
D000972:Antineoplastic Agents, Phytogenic; D053823:Hedgehog Proteins; D015534:Trans-Activators; D014704:Veratrum Alkaloids; C000541:cyclopamine