title: Induction of ResDE-dependent gene expression in Bacillus subtilis in response to nitric oxide and nitrosative stress.
abstract: Transcription of ResDE-controlled genes in Bacillus subtilis was induced by sodium nitroprusside and nitric oxide. This induction requires the sensor kinase ResE and the response regulator ResD. Among members of the ResDE regulon, only the flavohemoglobin gene was induced by nitrosative stress via both a ResDE-dependent mechanism and an unidentified ResDE-independent mechanism.
authors.affiliation: Department of Biochemistry and Molecular Biology, OGI School of Science and Engineering, Oregon Health and Science University, Beaverton, Oregon 97006-8921, USA. mnakano@bmb4.ogi.edu
authors.forename: Michiko M
authors.initials: MM
authors.lastname: Nakano
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D004268:DNA-Binding Proteins; D015964:Gene Expression Regulation, Bacterial / Q000187:drug effects*; D006420:Hemeproteins / Q000235:genetics; D009569:Nitric Oxide / Q000494:pharmacology*; D009599:Nitroprusside / Q000494:pharmacology; D018085:Regulon / Q000187:drug effects; D014157:Transcription Factors; D014158:Transcription, Genetic / Q000187:drug effects
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D006420:Hemeproteins; C100386:ResD protein, Bacillus subtilis; D014157:Transcription Factors; D009599:Nitroprusside; D009569:Nitric Oxide