title: Effect of sucrose and safflower oil preloads on short term appetite and food intake of young men.
abstract: The effects of carbohydrate and fat on satiety have been examined primarily through meal composition studies. The purpose of this study was to compare the effects of pure sucrose and safflower oil, isovolumetric beverage preloads, on appetite (measured every 15 minutes by visual analogue scales) and food intake 60 minutes later. Young men consumed 0, 418, 836 and 1254 kJ of sucrose in the first two experiments and these same doses of safflower oil in the third. Finally, the largest doses of sucrose and safflower oil were compared. Sucrose, but not safflower oil, suppressed average appetite compared with control. In experiment 2, food intake was reduced (p<0.05) by 518 kJ after the 418 and 836 kJ preloads and by 1129 kJ after the 1254 kJ sucrose preload. Only the 1254 kJ dose of safflower oil significantly suppressed food intake by 480 kJ in the third experiment. When the 1254 kJ doses were compared directly, sucrose suppressed food intake by 653 kJ compared with control where as safflower oil did not. It is concluded that, in the short-term, sucrose produces a dose dependent reduction in appetite and food intake that is greater than that produced by safflower oil.
authors.affiliation: Department of Nutritional Sciences, University of Toronto, Toronto, Canada.
authors.forename: D M
authors.initials: DM
authors.lastname: Woodend
authors.forename: G H
authors.initials: GH
authors.lastname: Anderson
mesh_terms: D000328:Adult; D001066:Appetite / Q000187:drug effects*; D015992:Body Mass Index; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects*; D006801:Humans; D008297:Male; D012450:Safflower Oil / Q000494:pharmacology*; D012527:Satiation; D013395:Sucrose / Q000494:pharmacology*
chemical_list: D013395:Sucrose; D012450:Safflower Oil