title: Toxic shock syndrome following cessation of prophylactic antibiotics in a child with a 2% scald.
abstract: Toxic shock syndrome (TSS) is a rare but serious complication of burns in children. Symptoms usually start within 3 days of the burn injury and even children with minor burns can be susceptible. Prompt diagnosis and rapid treatment is crucial in limiting the morbidity associated with this condition. We report here a 19-month-old child with a 2% scald who developed TSS following cessation of a 5-day course of flucloxacillin. This case highlights a number of issues regarding the use of prophylactic antibiotics and TSS as well as illustrating the continuing need to educate parents concerning the importance of seeking a prompt medical opinion if the child becomes ill following even a minor burn injury.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Salisbury District Hospital, Odstock, Salisbury, Wiltshire, UK. 1davidjohnson@excite.co.uk
authors.forename: D
authors.initials: D
authors.lastname: Johnson
authors.forename: P D R
authors.initials: PD
authors.lastname: Pathirana
mesh_terms: D001427:Bacterial Toxins; D002056:Burns / Q000150:complications* / Q000382:microbiology; D004768:Enterotoxins / Q000097:blood; D005260:Female; D005436:Floxacillin / Q000627:therapeutic use; D005440:Fluid Therapy; D006801:Humans; D007223:Infant; D010406:Penicillins / Q000627:therapeutic use; D012772:Shock, Septic / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D016038:Skin Transplantation; D013207:Staphylococcal Skin Infections / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D018089:Superantigens
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D010406:Penicillins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; D005436:Floxacillin