title: Lemierre's syndrome as a consequence of acute supraglottitis.
abstract: Lemierre's syndrome comprises internal jugular vein thrombosis following oropharyngeal sepsis and is a rare and serious condition. It is most commonly caused by the anaerobe Fusobacterium necrophorum and typically presents as metastatic sepsis to the lungs and joints. Thrombosis is demonstrated by computed tomography (CT) of the neck, and it is routinely treated with intravenous antibiotics and anti-coagulation. We describe a case of Lemierre's syndrome following acute supraglottitis. The clinical features were of retrograde intracranial thrombosis, rather than the more usual metastatic sepsis.
authors.affiliation: Department of Ear, Nose and Throat Surgery, Wexham Park Hospital, Slough, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: Hope
authors.forename: Nigel
authors.initials: N
authors.lastname: Bleach
authors.forename: Sabour
authors.initials: S
authors.lastname: Ghiacy
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D005260:Female; D005931:Glottis; D006801:Humans; D020767:Intracranial Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*; D007601:Jugular Veins / Q000000981:diagnostic imaging; D007827:Laryngitis / Q000150:complications*; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*