title: [Lisch nodules: description of 2 clinical cases and their significance].
abstract: We report two cases of Lisch nodules in both eyes in two women. It was the only ocular manifestation of their Von Recklinghausen disease. The other general signs of their disease were cutaneous neurofibromas. Lisch nodules are melanocytic hamartomas consisting of melanocytic cells containing various quantities of pigment. They can be found in 90 to 100% of neurofibromatosis patients over 6 years of age. They are practically pathognomonic of type 1 neurofibromatosis and their finding is an important diagnostic argument. They must be distinguished from other iris nodules: nevus, melanoma, inflammatory nodules, and development anomalies.
authors.affiliation: Service d'Ophtalmologie, CHU de Fort de France, Hôpital Pierre Zobda Quitman, BP 632, 97261 Fort de France.
authors.forename: L
authors.initials: L
authors.lastname: Menard
authors.forename: G
authors.initials: G
authors.lastname: Magnaval
authors.forename: A
authors.initials: A
authors.lastname: Donnio
authors.forename: L
authors.initials: L
authors.lastname: Ayeboua
authors.forename: R
authors.initials: R
authors.lastname: Richer
authors.forename: H
authors.initials: H
authors.lastname: Merle
mesh_terms: D000328:Adult; D005260:Female; D006222:Hamartoma / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007499:Iris Diseases / Q000175:diagnosis* / Q000209:etiology; D008875:Middle Aged; D017253:Neurofibromatoses / Q000150:complications*