Pharmaceutical considerations in aerosol drug delivery.
Aerosolized drug delivery has been used for over 50 years, but its quality and scope continue to increase. Three factors affect this form of drug delivery: the nebulizer, the compressor, and the actual drug preparation. As technology and knowledge improve, this delivery system also improves. Patients with cystic fibrosis, in particular, can benefit significantly from this form of therapy.
Kuhn
Robert J
RJ
Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington 40536-0293, USA.
D000280:Administration, Inhalation; D000336:Aerosols; D000367:Age Factors; D000617:Aminoglycosides / Q000008:administration & dosage / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002626:Chemistry, Pharmaceutical / Q000379:methods; D003550:Cystic Fibrosis / Q000188:drug therapy; D004304:Dosage Forms; D004305:Dose-Response Relationship, Drug; D004339:Drug Compounding / Q000379:methods*; D016503:Drug Delivery Systems; D006801:Humans; D009330:Nebulizers and Vaporizers; D014031:Tobramycin / Q000008:administration & dosage / Q000627:therapeutic use
D000336:Aerosols; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D004304:Dosage Forms; D014031:Tobramycin