Vitamin A, vitamin E and carotenoid status and metabolism during ageing: functional and nutritional consequences (VITAGE PROJECT).
Among the nutritional factors contributing to maintain health during ageing, fat-soluble vitamins (FSV) are crucial to protect against free radical-generated degenerative processes or impaired efficiency of the immune system. However, no sound scientific evidence is able to confirm specific dietary needs in vitamin A, vitamin E and carotenoids for the healthy elderly. VITAGE project aims at providing such evidence by undertaking studies on male volunteers from 3 European countries, aged between 20-75 years. Biomarkers and variables related to status, metabolism and functions will be measured either in steady-state conditions, or during dietary depletion and repletion in FSV. Original, yet already developed, methodologies will provide clear information about the physiological characteristics of vitamin A, vitamin E and carotenoids. Simultaneously, marketing opportunities for FSV-enriched dietetic foods, specifically designed for the elderly will be determined. The scientific and economical evidence obtained in this project will provide the basis to implement a EU nutritional policy towards the elderly and to develop a new sector of dietetic food products.
Rock
E
E
INRA. UMMM. CRNH, Centre de Theix, Saint-Genès Champanelle, France.
Winklhofer-Roob
B M
BM
Ribalta
J
J
Scotter
M
M
Vasson
M P
MP
Brtko
J
J
Brigelius-Flohe
R
R
Bronner
A
A
Azaïs-Braesco
V
V
D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D002338:Carotenoids / Q000378:metabolism*; D005062:European Union; D006801:Humans; D008297:Male; D008875:Middle Aged; D018673:Nutrition Policy; D009751:Nutritional Requirements; D009752:Nutritional Status; D014801:Vitamin A / Q000378:metabolism*; D014810:Vitamin E / Q000378:metabolism*
D014801:Vitamin A; D014810:Vitamin E; D002338:Carotenoids