The cost of antibiotic resistance: effect of resistance among Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudmonas aeruginosa on length of hospital stay.
To assess the effect of antimicrobial resistance on length of hospital stay, a case-control study compared infections due to four nosocomial pathogens. Significantly increased lengths of stay were associated with infections due to methicillin-resistant Staphylococcus aureus, extended-spectrum beta-lactamase-producing Klebsiella pneumoniae, and carbapenem-resistant Acinetobacter baumannii or Pseudomonas aeruginosa. Infections with resistant pathogens are associated with prolonged hospitalization.
D000150:Acinetobacter / Q000187:drug effects / Q000472:pathogenicity; D000368:Aged; D001424:Bacterial Infections / Q000191:economics / Q000453:epidemiology*; D016022:Case-Control Studies; D003428:Cross Infection / Q000191:economics / Q000453:epidemiology*; D004351:Drug Resistance; D017052:Hospital Mortality; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000472:pathogenicity; D007902:Length of Stay / Q000191:economics*; D009519:New York City / Q000453:epidemiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000472:pathogenicity; D013211:Staphylococcus aureus / Q000187:drug effects / Q000472:pathogenicity