title: Novel intraoperative cerebral blood flow monitoring by laser-Doppler scanner.
abstract: Laser-Doppler (LD) flowmetry was used to measure tissue perfusion non-invasively and continuously during neurosurgical operations using an LD scanner. Scanning was usually completed in 20 seconds. Measurements were processed in software to provide a color-coded image of the tissue perfusion. Moreover, the measurement data, expressed in LD-units, could be used for statistical data analysis. No physical contact was necessary between the scanning device and the exposed brain tissue. The imager provided two-dimensional microvascular flow maps non-invasively and quantitatively during brain operations, and could show the CO2 reactivity in the vessels. LD scanning flowmetry is a promising intraoperative monitoring method for cerebral blood flow changes.
authors.affiliation: Department of Neurosurgery, Nara Medical University, Kashihara, Nara. nakasehi@nmu-gw.naramed-u.ac.jp
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakase
authors.forename: Takanobu
authors.initials: T
authors.lastname: Kaido
authors.forename: Shuzo
authors.initials: S
authors.lastname: Okuno
authors.forename: Tohru
authors.initials: T
authors.lastname: Hoshida
authors.forename: Toshisuke
authors.initials: T
authors.lastname: Sakaki
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical; D001783:Blood Flow Velocity; D001921:Brain / Q000098:blood supply / Q000601:surgery; D002245:Carbon Dioxide / Q000097:blood; D002560:Cerebrovascular Circulation; D003116:Color; D003196:Computer Graphics; D003626:Data Display; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation*; D020768:Middle Cerebral Artery / Q000601:surgery; D016343:Monitoring, Intraoperative / Q000295:instrumentation*; D009072:Moyamoya Disease / Q000150:complications / Q000601:surgery; D010781:Photography; D020521:Stroke / Q000209:etiology / Q000601:surgery; D013699:Temporal Arteries / Q000601:surgery
chemical_list: D002245:Carbon Dioxide