Breast lymphoma associated with breast implants: two case-reports and a review of the literature.
Breast lymphoma is a rare entity consisting mostly of B-cell lymphomas that affects older women. Very few cases of breast lymphomas of T-cell origin have been reported. Even fewer cases of breast lymphomas have been reported in women who have received breast implants. Silicone, a frequent component of breast implants, has been extensively investigated as a possible etiologic agent for some neoplasias and autoimmune disorders, including non-Hodgkin's lymphoma. We herein report two unusual cases of anaplastic large cell lymphoma of T-cell phenotype developing in the breasts of women who had received breast implants.
Gaudet
Guylaine
G
Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
Friedberg
Jonathan W
JW
Weng
Andrew
A
Pinkus
Geraldine S
GS
Freedman
Arnold S
AS
D000368:Aged; D000369:Aged, 80 and over; D015703:Antigens, CD / Q000032:analysis; D018427:Breast Implants / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D016403:Lymphoma, Large B-Cell, Diffuse / Q000139:chemically induced / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D020034:Silicone Gels / Q000009:adverse effects
D015703:Antigens, CD; D020034:Silicone Gels