Oily chemoembolization of pancreatic head adenocarcinoma.
Oily chemoembolization is a known method of treatment for hepatic malignancies but was never used for pancreatic cancer. We report the case of a 48-year-old patient with unresectable adenocarcinoma of the pancreatic head treated by repeated chemoembolizations of the feeding (gastroduodenal) artery with gemcitabine-in-lipiodol. After 10 procedures there was a marked decrease in tumor. Radiologic examinations showed no signs of viable tumor. The patient is alive and symptom-free 22 months after the start of treatment. Oily chemoembolization should be investigated as a technically simple, safe, and potentially effective palliative management of unresectable pancreatic head carcinoma.
Tarazov
P G
PG
St. Petersburg Research Institute of Roentgenology and Radiation Therapy, Russia. crirr@peterlink.ru
Pavlovskij
A V
AV
Granov
D A
DA
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000628:therapy*; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D016461:Chemoembolization, Therapeutic; D003131:Combined Modality Therapy; D003287:Contrast Media / Q000008:administration & dosage; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D003287:Contrast Media; D003841:Deoxycytidine; D007459:Iodized Oil; D000093542:Gemcitabine