Clavosolides A and B, dimeric macrolides from the Philippines sponge Myriastra clavosa.
A specimen of the sponge Myriastra clavosa from the Philippines contained two dimeric macrolides, clavosolides A and B. Clavosolide A is a symmetrical dimer, while clavosolide B is rendered unsymmetrical by the replacement of one of the methoxyl groups by a hydroxyl group. The structures of the clavosolides were elucidated by interpretation of spectroscopic data.
Rao
M Rama
MR
Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093-0212, USA.
Faulkner
D John
DJ
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D018942:Macrolides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010679:Philippines; D011161:Porifera / Q000737:chemistry*; D013237:Stereoisomerism
D018942:Macrolides; C455699:clavosolide A; C455700:clavosolide B