title: Usefulness of power Doppler and contrast-enhanced sonography in the differentiation of hyperechoic renal masses.
abstract: BACKGROUND
  In a prospective study, we compared power Doppler with and without contrast medium in the depiction of vascularity for the characterization of hyperechoic renal lesions.
  
  
  METHODS
  Forty-one hyperechoic renal expansive lesions (29 benign, 12 malignant) in 32 patients were studied with power-Doppler ultrasonography before and after administration of an echo-enhancing agent (Levovist Schering AG, Berlin, Germany). Vascular architecture of the lesions was categorized into five different patterns.
  
  
  RESULTS
  Power Doppler ultrasonography showed vascular structures in 25 lesions. The study enhanced with Levovist showed vascularity in eight of 16 lesions not seen on the unenhanced study. The characterization of vascular patterns with unenhanced power Doppler ultrasonography improved diagnostic accuracy compared with gray-scale ultrasonography (59% vs. 32%). The combination of B mode and power Doppler produced even greater diagnostic accuracy (78%), independent of the administration of echo-enhancing agent. Levovist administration was useful in the differential diagnosis between pseudotumor and neoplasm.
  
  
  CONCLUSIONS
  The use of sonographic contrast agent did not increase the diagnostic accuracy of power Doppler in the differential diagnosis of hyperechoic renal lesions but was advantageous for the characterization of suspected pseudomasses.
authors.affiliation: Institute of Radiological Sciences, Policlinico G. Martino, University of Messina, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ascenti
authors.forename: G
authors.initials: G
authors.lastname: Zimbaro
authors.forename: S
authors.initials: S
authors.lastname: Mazziotti
authors.forename: M
authors.initials: M
authors.lastname: Gaeta
authors.forename: N
authors.initials: N
authors.lastname: Settineri
authors.forename: E
authors.initials: E
authors.lastname: Scribano
mesh_terms: D018207:Angiomyolipoma / Q000000981:diagnostic imaging; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides; D018608:Ultrasonography, Doppler
chemical_list: D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508