Periocular neurofibrosarcoma in a horse.
A periocular neurofibrosarcoma was debulked and treated with intralesional cisplatin in a 5-year-old Thoroughbred mare. The horse presented with a 1-year history of a large slowly progressing subcutaneous mass over the right supraorbital process. The mass was surgically debulked, and intralesional cisplatin (1.0 mg/cm3) was injected in 3 doses at 2 weeks, 5 weeks, and 8 weeks postoperatively. No recurrence was noted over a 15-month follow-up period. Histopathology of the mass indicated neurofibrosarcoma.
Strubbe
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Animal Eye Specialty Clinic, Stuart, FL 34994 USA.
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D006736:Horses; D018319:Neurofibrosarcoma / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*
D000970:Antineoplastic Agents; D002945:Cisplatin