Risk factors for vancomycin-resistant Enterococcus (VRE) infection in colonized patients with cancer.
To determine the risk factors for vancomycin-resistant Enterococcus (VRE) infection in colonized patients with cancer, we conducted a case-control study. According to multivariate analysis, the only significant factors were neutropenia (< 500 cells/mm3) for more than 1 week and the use of oral vancomycin. Therefore, colonized neutropenic patients with cancer who have previously used oral vancomycin are most prone to VRE infection.
Husni
Rola
R
The University of Texas M.D. Anderson Cancer Center, Department of Infectious Diseases, Infection Control and Employee Health, Houston, Texas 77030, USA.
Hachem
Ray
R
Hanna
Hend
H
Raad
Issam
I
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000150:complications / Q000453:epidemiology*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology*; D016983:Enterococcus / Q000187:drug effects* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D012307:Risk Factors; D013781:Texas / Q000453:epidemiology; D014640:Vancomycin / Q000009:adverse effects; D020713:Vancomycin Resistance
D014640:Vancomycin