Inhibiting effect of beta-cyclodextrin on thymine dimerization photosensitized by para-aminobenzoic acid.
Beta-cyclodextrin can act as an efficient inhibitor of the photosensitized dimerization of thymine by para-aminobenzoic acid (PABA) in aqueous solution. This can be explained by considering the formation of an inclusion complex between PABA and beta-cyclodextrin.
Nowakowska
Maria
M
Faculty of Chemistry, Jagiellonian University, Kraków, Poland. nowakows@chemia.uj.edu.pl
Grebosz
Mirosław
M
Smoluch
Mirosława
M
Tatara
Wiktor
W
D010129:4-Aminobenzoic Acid / Q000009:adverse effects*; D003505:Cyclodextrins / Q000494:pharmacology*; D004336:Drug Antagonism; D007700:Kinetics; D017319:Photosensitizing Agents / Q000009:adverse effects; D020011:Protective Agents / Q000494:pharmacology; D011740:Pyrimidine Dimers / Q000819:agonists / Q000037:antagonists & inhibitors*; D013473:Sunscreening Agents / Q000009:adverse effects*; D013941:Thymine / Q000737:chemistry / Q000378:metabolism / Q000528:radiation effects; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D017319:Photosensitizing Agents; D020011:Protective Agents; D011740:Pyrimidine Dimers; D013473:Sunscreening Agents; D047392:beta-Cyclodextrins; C031215:betadex; D013941:Thymine; D010129:4-Aminobenzoic Acid