title: Keratoelastoidosis marginalis.
abstract: BACKGROUND
  Keratoelastoidosis marginalis is a rare disease that is a variant of solar elastosis. Long-term ultraviolet radiation exposure and chronic trauma secondary to manual labor are considered to be inciting factors.
  
  
  OBJECTIVE
  To outline the clinical and histological features of this disorder.
  
  
  METHODS
  We report two cases and review the literature.
  
  
  RESULTS
  Both patients had persistence of their disease despite multiple topical treatment regimens.
  
  
  CONCLUSIONS
  Keratoelastoidosis marginalis is a chronic and progressive disease that is difficult to treat. The differential includes focal acral hyperkeratosis and acrokeratoelastoidosis.
authors.affiliation: Department of Dermatology, Wake Forest University, Winston-Salem, North Carolina, USA.
authors.forename: Yebabe M
authors.initials: YM
authors.lastname: Mengesha
authors.forename: John D
authors.initials: JD
authors.lastname: Kayal
authors.forename: Robert A
authors.initials: RA
authors.lastname: Swerlick
mesh_terms: D005260:Female; D006229:Hand Dermatoses / Q000473:pathology*; D006801:Humans; D007642:Keratosis / Q000473:pathology*; D008875:Middle Aged