Synthesis, antimicrobial and molluscicidal activities of new benzimidazole derivatives.
A series of benzimidazole Schiff's bases, thiosemicarbazides were synthesized, azole ring systems as 1,3,4-triazole, 1,3,4-oxadiazole were prepared. 1-Methylbenzimidazole incorporated to substituted dithio-carbamate, thiophenol, diethylamine via acetamido group were synthesized. A series of pyrimidinobenzimidazoles, triazinobenz-imidazoles, and 2-(acetonylamino)-1-methylbenzimidazole were prepared. The antimicrobial and molluscicidal activities of some newly prepared compounds were carried out.
Nofal
Z M
ZM
Therapeutical Chemistry Dept, National Research Centre, Dokki, Cairo, Egypt.
Fahmy
H H
HH
Mohamed
H S
HS
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology* / Q000633:toxicity; D001700:Biomphalaria / Q000502:physiology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003470:Culture Media; D005658:Fungi / Q000187:drug effects; D007202:Indicators and Reagents; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008975:Molluscacides / Q000138:chemical synthesis* / Q000633:toxicity*; D013055:Spectrophotometry, Infrared
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001562:Benzimidazoles; D003470:Culture Media; D007202:Indicators and Reagents; D008975:Molluscacides