title: Sleep problems in a very old population: drug use and clinical correlates.
abstract: BACKGROUND
  Complaints of disturbed or dissatisfied sleep are common among older people. This study aimed to evaluate the prevalence of sleep problems in very old persons and its relation to physical and mental health and drug use.
  
  
  METHODS
  This is a cross-sectional analysis of sleep problems in a population of old persons living in Stockholm, Sweden. There were 641 subjects aged 81+ years; 77.8% were women, 91.4% were noninstitutionalized, and 68.6% lived alone. All persons underwent a comprehensive medical and psychiatric interview and examination. Sleep problems were assessed using the Clinical Psychopathological Rating Scale (CPRS). Covariates included chronic medical conditions, depression, dementia, pain, self-rated health, activities of daily living, use of hypnotics-sedatives, use of other psychotropic drugs, and use of nonpsychotropic drugs.
  
  
  RESULTS
  More than one third of subjects were identified with sleep problems. They were more common among women and persons using a higher number of drugs. Poor self-rated health, depression, and pain were related to the presence of sleep problems. Among persons with sleep problems and depression, only 19.2% used antidepressants, and 46.2% used hypnotics-sedatives. Among persons with sleep problems and pain, 63.2% used analgesics, and 47.0% used hypnotics-sedatives. One or more chronic diseases, use of hypnotics-sedatives, use of other psychotropic drugs, and use of nonpsychotropic drugs were also related to sleep problems. After multivariate analysis, factors significantly related to sleep problems were female gender, depression, pain, and hypnotic-sedative use.
  
  
  CONCLUSIONS
  Sleep problems were common in this very old population. These results suggest the importance of carefully assessing an older person's complaints to accurately diagnose and effectively treat sleep problems.
authors.affiliation: NEUROTEC, Karolinska Institute, Stockholm, Sweden. Maria.Stella.T.Giron@neurotec.ki.se
authors.forename: Maria Stella T
authors.initials: MS
authors.lastname: Giron
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Forsell
authors.forename: Cecilia
authors.initials: C
authors.lastname: Bernsten
authors.forename: Mats
authors.initials: M
authors.lastname: Thorslund
authors.forename: Bengt
authors.initials: B
authors.lastname: Winblad
authors.forename: Johan
authors.initials: J
authors.lastname: Fastbom
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D003430:Cross-Sectional Studies; D003863:Depression / Q000150:complications; D004363:Drug Utilization; D005260:Female; D006304:Health Status; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D008603:Mental Health; D010146:Pain / Q000150:complications; D015995:Prevalence; D017678:Sex Distribution; D012893:Sleep Wake Disorders / Q000453:epidemiology* / Q000209:etiology; D013548:Sweden
chemical_list: D006993:Hypnotics and Sedatives