title: Prosthodontic biomaterials and adverse reactions: a critical review of the clinical and research literature.
abstract: Prosthodontic biomaterials include impression materials, luting cements, and restorative materials. They consist of metals and alloys ceramics, and polymer materials and are retained in patients for <60 min or for decades. Oral release of compounds from biomaterials occurs, and adverse reactions may follow dental treatment. Especially in allergically vulnerable patients contact allergy may occur. There are reports from many different countries on contact allergy from gold/palladium alloys, components from polymer-based materials, chromium/cobalt alloys, and nickel. Notifications on adverse reactions in Norway, Sweden, and England are handled by a registry in which patient reactions and occupational exposure are recorded. Data from The Adverse Reaction Unit in Bergen and Umeå have been a most valuable basis in extending knowledge in a field of current interest in dentistry. A review of the clinical and research literature relating to prosthodontic biomaterials and adverse reactions shows that reliable methods seem necessary to expose the frequency of adverse reactions in general dentistry, including prosthodontic treatment.
authors.affiliation: Department of Odontology-Oral Pharmacology, University of Bergen, Norway. henning.lygre@odont.uib.no
authors.forename: Henning
authors.initials: H
authors.lastname: Lygre
mesh_terms: D000818:Animals; D003722:Dental Alloys / Q000009:adverse effects; D003738:Dental Cements / Q000009:adverse effects; D003760:Dental Impression Materials / Q000009:adverse effects; D003764:Dental Materials / Q000009:adverse effects* / Q000737:chemistry; D003776:Dental Porcelain / Q000009:adverse effects; D017266:Dental Prosthesis / Q000009:adverse effects*; D003813:Dentistry; D003877:Dermatitis, Contact / Q000209:etiology; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology; D016273:Occupational Exposure / Q000706:statistics & numerical data
chemical_list: D003722:Dental Alloys; D003738:Dental Cements; D003760:Dental Impression Materials; D003764:Dental Materials; D003776:Dental Porcelain