title: Chronic alcoholism: a common risk factor in oral cancer and alcoholic cirrhosis.
abstract: Oral cancer and alcoholic cirrhosis are relatively common diseases encountered in medical and dental practices. This article reviews the clinical, pathophysiological, and epidemiological characteristics of these two conditions. A major risk factor common to both oral cancer and alcoholic cirrhosis is the excessive use of alcohol. A challenge for practitioners and researchers is to become mindful of the connection between oral cancer and alcoholic cirrhosis. Earlier studies exploring these relationships and potential mechanisms are discussed.
authors.affiliation: Department of Pediatric Dentistry, Louisiana State University, School of Dentistry, New Orleans, Louisiana, USA.
authors.forename: T M
authors.initials: TM
authors.lastname: Perkins
authors.forename: I
authors.initials: I
authors.lastname: Perkins
mesh_terms: D000079:Acetaldehyde / Q000009:adverse effects; D000328:Adult; D000437:Alcoholism / Q000150:complications*; D044383:Black People; D002273:Carcinogens / Q000009:adverse effects; D000431:Ethanol / Q000009:adverse effects; D005260:Female; D022781:Hepatocytes / Q000187:drug effects; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000209:etiology* / Q000503:physiopathology; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D015996:Survival Rate
chemical_list: D002273:Carcinogens; D000431:Ethanol; D000079:Acetaldehyde