Cellular and molecular basis for the formation of lamina-specific thalamocortical projections.
The neocortex is composed of a characteristic layered structure, which is a basis of extrinsic and intrinsic cortical connections. In recent years the cellular and molecular mechanisms, which are responsible for the formation of lamina-specific connections, have been explored by extensive molecular and in vitro studies. This article attempts to address what cell-cell interactions are required for axonal targeting and what molecules regulate cellular events, focusing upon the development of the thalamocortical projection.
Yamamoto
Nobuhiko
N
Division of Biophysical Engineering, Graduate School of Engineering Science, Osaka University, Toyonaka, Osaka 560-8531, Japan. nob-yama@bpe.es.osaka-u.ac.jp
D000818:Animals; D001369:Axons / Q000502:physiology; D002540:Cerebral Cortex / Q000166:cytology* / Q000502:physiology*; D006801:Humans; D009434:Neural Pathways / Q000166:cytology / Q000502:physiology; D013788:Thalamus / Q000166:cytology* / Q000502:physiology*