title: [The role of bioactive food additives in therapeutic and prophylactic nutrition].
abstract: The efficiency of therapeutic and prophylactic nutrition (TPN) is determined by its scientific basis. The diets should be created with consideration for pathogenetic mechanisms of the effects of occupational hazards, energy expenditures, ecology of the habitat, national features of nutrition, and unfavorable factors associated with the risk of the underlying and concomitant diseases. Use of bioactive food additives (BFA) essentially facilitated the development and utilization of TPN under conditions of hazardous production and unfavorable ecology. The technology of making a perspective BFA Vitagmal has been developed. Biomedical evaluation of this BFA was carried out: protein, carbohydrate, and mineral metabolism, morphology of organs and tissues in experimental animals fed Vitagmal, and its effects on clinical and physiological status of man were studied. The effect of BFA on the metabolism was studied in patients with metabolic alimentary obesity. The results demonstrated a pronounced health-fortifying antioxidant effect of Vitagmal, which had a favorable impact on cardiovascular and central nervous functions, stimulated the metabolic processes, had a slight "protective effect" in ethanol intoxication, and no side effects. This recommends Vitagmal for wide use in therapeutic and prophylactic medicine.
authors.forename: V A
authors.initials: VA
authors.lastname: Dotsenko
authors.forename: I V
authors.initials: IV
authors.lastname: Medvedeva
authors.forename: E V
authors.initials: EV
authors.lastname: Zhiliakov
mesh_terms: D005503:Food Additives / Q000494:pharmacology* / Q000627:therapeutic use; D006304:Health Status; D006801:Humans; D009752:Nutritional Status / Q000187:drug effects*
chemical_list: D005503:Food Additives