Temporal sequence of response to unilateral GPi pallidotomy of motor symptoms in Parkinson's disease.
The present study was performed to determine the temporal sequence of the response to unilateral MRI/microelectrode-guided pallidotomy of each cardinal symptom in Parkinson's disease (PD). For this purpose, we performed a quantitative assessment of motor functions in 19 patients with PD at several time points up to 6 months following surgery. We here report that although all the motor signs were significantly improved 6 months after pallidotomy, the temporal sequence of tremor response was different from those of other symptoms.
Goto
S
S
Department of Neurosurgery, Kumamoto University Medical School, Kumamoto, Japan. sgoto@kaiju.medic.kumamoto-u.ac.jp
Hamasaki
T
T
Nishikawa
S
S
Okamura
A
A
Yoshikawa
M
M
Yamada
K
K
Soyama
N
N
Mita
S
S
Ushio
Y
Y
D000368:Aged; D000704:Analysis of Variance; D004599:Electric Stimulation Therapy / Q000379:methods; D005260:Female; D005917:Globus Pallidus / Q000502:physiology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008839:Microelectrodes; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D019957:Motor Skills Disorders / Q000503:physiopathology / Q000601:surgery; D010300:Parkinson Disease / Q000503:physiopathology* / Q000601:surgery*; D013997:Time Factors