title: Pleomorphic adenoma of the lachrymal gland: presentation of a clinical case of relapse.
abstract: Pleomorphic adenoma affecting the lachrymal gland requires a well-grounded clinical and therapeutic protocol to avoid the risk of malignant transformation or disease recurrence, which is quite dangerous at this site. The authors present a clinical case of pleomorphic adenoma recurrence affecting the right lachrymal gland in a patient who first underwent a biopsy, with subsequent resection of the neoplasm. The authors also review the clinical and radiological features enabling a differential diagnosis and describe the radical "exenteratio orbitae" surgery for pleomorphic adenoma recurrence 7 years after the first operation, which was performed because of total derangement of the orbital cavity. The patient remains disease-free 5 years after this surgical treatment. Therefore, it turns out that an incisional biopsy carries a higher biological cost for the patient.
authors.affiliation: Maxillofacial Surgery Division, La Sapienza University, Rome, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Becelli
authors.forename: Andrea
authors.initials: A
authors.lastname: Carboni
authors.forename: Andrea
authors.initials: A
authors.lastname: Cassoni
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Renzi
authors.forename: Giorgio
authors.initials: G
authors.lastname: Iannetti
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology / Q000601:surgery*; D001706:Biopsy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000209:etiology*; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D017233:Orbit Evisceration