The gut microflora and intestinal epithelial cells: a continuing dialogue.
The mammalian intestinal epithelium effectively performs its physiological functions in a microbe-rich environment, while the prokaryotic population thrives amidst efficient cellular defenses. Recent delineation of the mechanisms by which bacteria communicate with their eukaryotic hosts and the cellular sites that microbial signals act in may shed light on these complex interactions.
Neish
Andrew S
AS
Epithelial Pathobiology Unit, Department of Pathology, Emory University School of Medicine, 105F Whitehead Bld, 615 Michaels Street, Atlanta, GA 30322, USA. aneish@emory.edu
D018407:Bacterial Physiological Phenomena; D004755:Enterobacteriaceae / Q000502:physiology; D004847:Epithelial Cells / Q000382:microbiology; D006790:Host-Parasite Interactions; D006801:Humans; D007249:Inflammation / Q000276:immunology / Q000382:microbiology; D007375:Interleukin-1 / Q000378:metabolism; D007413:Intestinal Mucosa / Q000276:immunology / Q000382:microbiology* / Q000502:physiology; D008954:Models, Biological; D016328:NF-kappa B / Q000378:metabolism; D018124:Receptors, Tumor Necrosis Factor / Q000378:metabolism
D007375:Interleukin-1; D016328:NF-kappa B; D018124:Receptors, Tumor Necrosis Factor