Meconium thorax: A case of Bochdalek hernia and cecal perforation in a neonate with Job's syndrome.
Meconium peritonitis most often is associated with congenital intestinal obstruction and meconium ileus. Uncommonly, other etiologies are identified. Hyperimmunoglobulin E syndrome (Job's syndrome) is a rare genetic disorder that is characterized by recurrent staphylococcal respiratory and skin infections in addition to elevated serum IgE levels. There have been 2 previously reported cases of intestinal complications associated with Job's syndrome. The current case is the third such case and is the first report of meconium peritonitis in a patient with hyperimmunoglobulin E syndrome. The patient presented with a meconium thorax as a result of a concurrent congenital diaphragmatic hernia.
Butterworth
Sonia A
SA
University of British Columbia, Vancouver, British Columbia, Canada.
Webber
Eric M
EM
D002432:Cecum / Q000002:abnormalities; D003108:Colonic Diseases / Q000150:complications* / Q000601:surgery; D005260:Female; D006548:Hernia, Diaphragmatic / Q000150:complications* / Q000601:surgery; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D007416:Intestinal Perforation / Q000150:complications* / Q000601:surgery; D008297:Male; D008470:Meconium; D009130:Muscle, Smooth / Q000002:abnormalities; D010538:Peritonitis / Q000209:etiology*; D011247:Pregnancy; D013896:Thoracic Diseases / Q000150:complications* / Q000601:surgery