title: Short-term outcome and prognosis of acute low-tone sensorineural hearing loss by administration of steroid.
abstract: Acute low-tone hearing loss (ALHL) is a typical type of hearing loss in Ménière's disease and thought to be caused by endolymphatic hydrops in the inner ear. We treated 40 patients with ALHL by administration of the steroid and the early outcome and prognosis of the hearing level was retrospectively evaluated. The prognosis was generally determined within 7-10 days after administration of steroid. High-dose steroid cured some patients who failed to recover with low-dose steroid therapy. Our results showed that steroid is one of the effective therapies for ALHL and supported that etiology of ALHL involves an immune response.
authors.affiliation: Department of Otolaryngology, Yamagata University School of Medicine, Yamagata, Japan. tafuse@med.id.yamagata-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Fuse
authors.forename: M
authors.initials: M
authors.lastname: Aoyagi
authors.forename: T
authors.initials: T
authors.lastname: Funakubo
authors.forename: A
authors.initials: A
authors.lastname: Sakakibara
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
mesh_terms: D000208:Acute Disease; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006319:Hearing Loss, Sensorineural / Q000188:drug therapy* / Q000276:immunology*; D006801:Humans; D007275:Injections, Intravenous; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013256:Steroids; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D013256:Steroids