Facile formation of chiral calixarene analogs incorporating cystine peptide into the macrocyclic ring.
Chiral calixarene analogs incorporating cystine peptide into their macrocyclic ring were easily prepared by the cyclization reactions of bis(chloromethyl)phenol-formaldehyde oligomers with cystine peptides in moderate yields. Circular dichroism (CD) spectra indicated the existence of the transmission of the chirality from peptide unit to phenol-formaldehyde oligomer moiety.
Ito
Kazuaki
K
Department of Chemistry and Chemical Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Japan. tm382@dipfr.dip.yz.yamagata-u.ac.jp
Tamura
Takafumi
T
Watanabe
Kazuhito
K
Ohba
Yoshihiro
Y
D047250:Calixarenes; D002942:Circular Dichroism; D003553:Cystine / Q000737:chemistry*; D046911:Macromolecular Substances; D010455:Peptides / Q000737:chemistry*; D013237:Stereoisomerism
D046911:Macromolecular Substances; D010455:Peptides; D047250:Calixarenes; D003553:Cystine