Addition of organozinc species to cyclic 1,3-diene monoepoxide.
[reaction: see text] The reaction of organozinc reagents (ZnEt(2), ZnPh(2)) with cyclic 1,3-diene monoepoxides in the presence of CF(3)COOH gave the cis-addition products. Lewis acids such as (CF(3)CO(2))(2)Zn and ZnCl(2) mediated the nucleophilic addition of ZnEt(2) to cyclooctadiene monoepoxide with high stereoselectivity.
Xue
Song
S
Department of Chemistry, University of Science and Technology of China, Hefei, 230026, P R China. xuesong@ustc.edu.cn
Li
Yali
Y
Han
Kaizhen
K
Yin
Wen
W
Wang
Meng
M
Guo
Qingxiang
Q