title: Antinuclear antibodies (ANA) in Gordon setters with symmetrical lupoid onychodystrophy and black hair follicular dysplasia.
abstract: Antinuclear antibodies (ANA) were demonstrated in 3 out of 10 Gordon setters with symmetrical lupoid onychodystrophy and in 5 out of 13 Gordon setters with black hair follicular dysplasia. Two dogs showed both symmetrical lupoid onychodystrophy and black hair follicular dysplasia, and one of these was ANA positive. The results suggest that symmetrical lupoid onychodystrophy and black hair follicular dysplasia in the Gordon setter might be autoimmune diseases that are pathogenetically related, which might indicate a common genetic predisposition.
authors.affiliation: Department of Immunology and Bloodbank, Trondheim University Hospital, Trondheim, Norway.
authors.forename: J
authors.initials: J
authors.lastname: Ovrebo Bohnhorst
authors.forename: I
authors.initials: I
authors.lastname: Hanssen
authors.forename: T
authors.initials: T
authors.lastname: Moen
mesh_terms: D000818:Animals; D000974:Antibodies, Antinuclear / Q000097:blood*; D001947:Breeding; D003872:Dermatitis / Q000235:genetics / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D004285:Dogs; D005260:Female; D005534:Foot Diseases / Q000235:genetics / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D020022:Genetic Predisposition to Disease; D018859:Hair Follicle / Q000473:pathology*; D006724:Hoof and Claw / Q000473:pathology*; D008297:Male
chemical_list: D000974:Antibodies, Antinuclear