[Levels of proinflammatory cytokines (Il-1 alpha, Il-6, TNF-alpha) in the semen plasma of male partners of infertile couples].
In semen plasma of 46 male partners of infertile couples the levels of proinflammatory cytokines such as IL-1 alpha, IL-6, TNF-alpha were quantified. The studied group was divided according to the number of leucocytes in an ejaculate into two subgroups (> 10(6)/ml and below 10(6)/ml). The levels of the studied cytokines were significantly elevated (p < 0.05) in patients with higher leucocyte count in the ejaculate. Testing the immunologic markers may be helpful in diagnostic process considering male partners of infertile couples.
Sikorski
R
R
III Katedry i Kliniki Ginekologii AM w Lublinie.
Kapeć
E
E
Krzemiński
A
A
Zaleska
W
W
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007375:Interleukin-1 / Q000378:metabolism*; D015850:Interleukin-6 / Q000378:metabolism*; D008297:Male; D012661:Semen / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
D015415:Biomarkers; D007375:Interleukin-1; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha