title: Serum antioxidant status of civil aircrew.
abstract: Objective. To study the serum antioxidant status in civil aircrew members who had more than 4000 h of cumulative flight hours, therefore exposed to a higher dose of cosmic radiation comparing to the dose received by ground residents. Method. Differences in the serum levels of total antioxidant capacity (TAOC), superoxide dismutase (SOD) and malondialdehyde (MDA) were investigated in 230 crew members, 37 local ground residents in Xinjiang, and 37 ground residents in Tianjin. Result. Significantly higher levels of all the three serum indexes were found in civil aircrew members. Serum levels of TAOC and SOD were higher in Xinjiang than in Tianjin ground residents, although no difference was found for MDA. Positive correlations were observed among the three serum indexes in this study. Conclusion. The elevated serum level of MDA in civil aircrew members deserves a proper attention by health care policy makers.
authors.affiliation: Nankai University School of Medicine, Tianjin, China.
authors.forename: J K
authors.initials: JK
authors.lastname: Liu
authors.forename: W R
authors.initials: WR
authors.lastname: Chen
authors.forename: H L
authors.initials: HL
authors.lastname: Zhang
authors.forename: Y J
authors.initials: YJ
authors.lastname: Feng
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: Y
authors.initials: Y
authors.lastname: Guo
authors.forename: S Y
authors.initials: SY
authors.lastname: Duan
authors.forename: X T
authors.initials: XT
authors.lastname: Peng
authors.forename: T P
authors.initials: TP
authors.lastname: Sun
authors.forename: B S
authors.initials: BS
authors.lastname: Jia
mesh_terms: D000328:Adult; D000337:Aerospace Medicine; D000367:Age Factors; D000975:Antioxidants / Q000032:analysis* / Q000528:radiation effects; D001359:Aviation; D003359:Cosmic Radiation; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood* / Q000528:radiation effects; D008875:Middle Aged; D012737:Sex Factors; D013482:Superoxide Dismutase / Q000097:blood* / Q000528:radiation effects
chemical_list: D000975:Antioxidants; D008315:Malondialdehyde; D013482:Superoxide Dismutase