title: [Legionellosis in HIV-1 infected patients. 4 case reports].
abstract: BACKGROUND
  Contrary to patients exhibiting cellular immunodepression, legionellosis is rare in HIV-infected patients. We report 4 cases.
  
  
  METHODS
  Four men aged 41 to 48 were infected by HIV-1. Three of them were treated with antiretroviral therapy. The clinical and biological manifestations were unspecific. Evolution was favourable with adapted antibiotic therapy (erythromycine for three patients and ciprofloxacine for the fourth).
  
  
  CONCLUSIONS
  Legionella pneumophila serotype Lp1 remains the principle etiological agent. Frequent use of contrimoxazole in prophylaxis against pneumocystosis and toxoplasmosis, macrolides, rifamycines and fluoroquinolones in the preventive and curative treatment of mycobacterioses, and the relative conservation of monocyte/macrophage function and immune repair with efficient antiretroviral therapy, may explain the low prevalence of this disease in HIV infections.
authors.affiliation: Services de Maladies Infectieuses et Tropicales, Hôpital Pitié-Salpêtrière, 47-83 bd de l'Hôpital, Paris.
authors.forename: D
authors.initials: D
authors.lastname: Sène
authors.forename: Ph
authors.initials: P
authors.lastname: Bossi
authors.forename: L
authors.initials: L
authors.lastname: Thomas
authors.forename: J
authors.initials: J
authors.lastname: Ghosn
authors.forename: V
authors.initials: V
authors.lastname: Zeller
authors.forename: E
authors.initials: E
authors.lastname: Caumes
authors.forename: C
authors.initials: C
authors.lastname: Katlama
authors.forename: F
authors.initials: F
authors.lastname: Bricaire
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000627:therapeutic use; D004917:Erythromycin / Q000008:administration & dosage / Q000627:therapeutic use; D015497:HIV-1; D006801:Humans; D007877:Legionnaires' Disease / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D004917:Erythromycin