title: Temporary auxiliary liver transplantation from a living donor to an adult recipient with familial amyloid polyneuropathy.
abstract: A 33-year-old patient with familial amyloid polyneuropathy (FAP) underwent temporary auxiliary partial orthotopic liver transplantation (APOLT) from a living donor with a small-for-size graft. The auxiliary left lobar graft, which weighed only 230 g, was orthotopically transplanted after resection of the recipient's left lobe. The right portal vein was transected to induce compensatory hypertrophy of the left lobar graft. Posttransplant computed tomography showed atrophy of the native liver and hypertrophy of the graft, the volume of which had increased to 446 ml by postoperative day 41. The remnant native liver was removed 6 weeks after APOLT, and there were no signs of liver dysfunction during the postoperative course. Our experience with this case suggests that temporary APOLT is the treatment of choice, guaranteeing a sufficient margin of safety for both donor and recipient, in living donor liver transplants for FAP where the donor's left lobe is disproportionately small.
authors.affiliation: 1st Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan 390-8621.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Ikegami
authors.forename: Seiji
authors.initials: S
authors.lastname: Kawasaki
authors.forename: Yasunari
authors.initials: Y
authors.lastname: Ohno
authors.forename: Hisanao
authors.initials: H
authors.lastname: Chisuwa
authors.forename: Koichi
authors.initials: K
authors.lastname: Urata
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Nakazawa
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Hashikura
authors.forename: Masaru
authors.initials: M
authors.lastname: Terada
authors.forename: Shinichi
authors.initials: S
authors.lastname: Miyagawa
authors.forename: Yo-ichi
authors.initials: Y
authors.lastname: Takei Yi
authors.forename: Takahiko
authors.initials: T
authors.lastname: Tokuda
authors.forename: Shu-ichi
authors.initials: S
authors.lastname: Ikeda Si
mesh_terms: D000328:Adult; D028227:Amyloid Neuropathies, Familial / Q000473:pathology / Q000601:surgery*; D005190:Family; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008099:Liver / Q000033:anatomy & histology; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D020858:Tissue and Organ Harvesting / Q000379:methods