title: Escherichia coli O157 infections and unpasteurised milk.
abstract: We report on two children with Escherichia coli O157 infection, one of whom developed haemolytic uraemic syndrome (HUS). Both had drunk raw cows  or goats  milk in the week before their illness. Molecular subtyping identified a sorbitol fermenting Escherichia coli O157:H isolate from a dairy cow. This isolate differed from Shiga toxin producing O157:H strains isolated from the 6 year old boy with HUS. This result underlines the need to search for other causes of infection, despite documented consumption of unpasteurised milk. In the second patient, human sorbitol non-fermenting O157:H isolates and animal isolates from goats were indistinguishable. The isolation of indistinguishable sorbitol non-fermenting Escherichia coli O157:H from contact animals supports the association between HUS and consumption of raw goats  milk, and re-emphasises the importance of pasteurising milk.
authors.affiliation: National Reference Laboratory for Enterohaemorrhagic Escherichia coli at the Federal Public Health Laboratory, Innsbruck, Austria.
authors.forename: F
authors.initials: F
authors.lastname: Allerberger
authors.forename: M
authors.initials: M
authors.lastname: Wagner
authors.forename: P
authors.initials: P
authors.lastname: Schweiger
authors.forename: H P
authors.initials: HP
authors.lastname: Rammer
authors.forename: A
authors.initials: A
authors.lastname: Resch
authors.forename: M P
authors.initials: MP
authors.lastname: Dierich
authors.forename: A W
authors.initials: AW
authors.lastname: Friedrich
authors.forename: H
authors.initials: H
authors.lastname: Karch
mesh_terms: D000818:Animals; D002417:Cattle; D002648:Child; D003967:Diarrhea / Q000382:microbiology*; D004927:Escherichia coli Infections / Q000382:microbiology*; D019453:Escherichia coli O157 / Q000302:isolation & purification*; D006041:Goats; D006463:Hemolytic-Uremic Syndrome / Q000382:microbiology; D006801:Humans; D008297:Male; D008892:Milk / Q000382:microbiology*