Normalization of nomenclature for peptide motifs as ligands of modular protein domains.
We propose a normalization of symbols and terms used to describe, accurately and succinctly, the detailed interactions between amino acid residues of pairs of interacting proteins at protein:protein (or protein:peptide) interfaces. Our aim is to unify several diverse descriptions currently in use in order to facilitate communication in the rapidly progressing field of signaling by protein domains. In order for the nomenclature to be convenient and widely used, we also suggest a parallel set of symbols restricted to the ASCII format allowing accurate parsing of the nomenclature to a computer-readable form. This proposal will be reviewed in the future and will therefore be open for the inclusion of new rules, modifications and changes.
Aasland
Rein
R
Department of Molecular Biology, University of Bergen, 5020 Bergen, Norway. aasland@mbi.uib.no
Abrams
Charles
C
Ampe
Christophe
C
Ball
Linda J
LJ
Bedford
Mark T
MT
Cesareni
Gianni
G
Gimona
Mario
M
Hurley
James H
JH
Jarchau
Thomas
T
Lehto
Veli Pekka
VP
Lemmon
Mark A
MA
Linding
Rune
R
Mayer
Bruce J
BJ
Nagai
Makoto
M
Sudol
Marius
M
Walter
Ulrich
U
Winder
Steve J
SJ
D001665:Binding Sites; D008024:Ligands; D010455:Peptides / Q000737:chemistry* / Q000145:classification; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D009626:Terminology as Topic; D018909:src Homology Domains
D008024:Ligands; D010455:Peptides; D011506:Proteins