title: Hepatic blood flow measurements with arterial and portal blood flow mapping in the human liver by means of xenon CT.
abstract: OBJECTIVE
  The purpose of this work was to quantify arterial and portal blood flows in the human liver and to create blood flow maps by means of xenon CT.
  
  
  METHODS
  Mathematical procedures were developed based on a simplified model having two tissue components: liver tissue and portal organ tissue. Xe-CT studies were performed on 10 healthy volunteers (ages 33.4 +/- 9.8 years), a patient with hepatocellular carcinoma (HCC), and a liver transplant recipient.
  
  
  RESULTS
  Arterial and portal blood flows for the healthy subjects were 36.7 +/- 5.2 and 65.2 +/- 22.0 ml/100 ml/min. In the HCC patient, arterial blood flow was shown to be dominant in the tumoral area. From the results of the liver recipient, it was demonstrated that obtaining lambda values is important for proper evaluation of blood flows.
  
  
  CONCLUSIONS
  Xe-CT can provide substantial information on hepatic blood flow quantitatively and visually with separation of arterial and portal components.
authors.affiliation: Anzai Medical Co, Ltd, Tokyo, Japan. sase@anzai-med.co.jp
authors.forename: Shigeru
authors.initials: S
authors.lastname: Sase
authors.forename: Morito
authors.initials: M
authors.lastname: Monden
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Oka
authors.forename: Keizo
authors.initials: K
authors.lastname: Dono
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Fukuta
authors.forename: Iekedo
authors.initials: I
authors.lastname: Shibata
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008099:Liver / Q000098:blood supply*; D008297:Male; D008962:Models, Theoretical; D012039:Regional Blood Flow; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014978:Xenon
chemical_list: D014978:Xenon