title: Mechanisms of pathogenesis in herpetic immunoinflammatory ocular lesions.
abstract: This article reviews possible mechanisms by which ocular infections with herpes simplex virus result in a blinding immunoinflammatory lesion in the cornea. We conclude that this immunoinflammatory response involves multiple immune mechanisms including autoimmunity.
authors.affiliation: Department of Microbiology, University of Tennessee, M409, Walter Life Sciences Building, Knoxville, TN 37996-0845, USA.
authors.forename: Shilpa P
authors.initials: SP
authors.lastname: Deshpande
authors.forename: Mei
authors.initials: M
authors.lastname: Zheng
authors.forename: Sujin
authors.initials: S
authors.lastname: Lee
authors.forename: Barry T
authors.initials: BT
authors.lastname: Rouse
mesh_terms: D000818:Animals; D015551:Autoimmunity / Q000276:immunology*; D006801:Humans; D016849:Keratitis, Herpetic / Q000276:immunology* / Q000473:pathology / Q000821:virology; D051379:Mice; D008807:Mice, Inbred BALB C; D016513:Mice, SCID; D008822:Mice, Transgenic; D018139:Simplexvirus / Q000276:immunology* / Q000472:pathogenicity