Long-term memory and levels-of-processing in autism.
Prior studies reported that long-term memory (LTM) was basically unimpaired in individuals with autism. However, people with autism have been found to perform worse than ability-matched controls when verbal materials to be remembered are semantically related. In normal subjects, semantic processing of verbal materials facilitates LTM better than 'shallow' (phonological or perceptual) processing, which is known as the levels-of-processing effect. In this study, the relationship between LTM and semantic processing was investigated using a levels-of-processing task. In Study 1, a levels-of-processing task was conducted on healthy volunteers, which confirmed the levels-of-processing effect with our task. In study 2, the same task was conducted on autistic subjects with mild or no mental retardation and ability-matched controls. The levels-of-processing effect was confirmed in the control group. Although overall performance in the two groups was comparable, the levels-of-processing effect was not found in the autistic group. LTM resulting from perceptual processing was better in the autistic group than in the control group, indicating superior "rote memory" in individuals with autism. Furthermore, the pattern of correlations between LTM performance and cognitive measures differed greatly between the two groups. The lack of the levels-of-processing effect, which has not been reported in other psychiatric or neuropathological conditions, suggests an abnormal relationship between semantic memory and episodic memory in individuals with autism.
Toichi
Motomi
M
Division of Child & Adolescent Psychiatry, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, OH, USA. motomi@mbj.sphere.ne.jp
Kamio
Yoko
Y
D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000150:complications* / Q000503:physiopathology; D003071:Cognition; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D008569:Memory Disorders / Q000209:etiology* / Q000503:physiopathology; D008606:Mental Processes; D012660:Semantics