Chronic alcoholism: a common risk factor in oral cancer and alcoholic cirrhosis.
Oral cancer and alcoholic cirrhosis are relatively common diseases encountered in medical and dental practices. This article reviews the clinical, pathophysiological, and epidemiological characteristics of these two conditions. A major risk factor common to both oral cancer and alcoholic cirrhosis is the excessive use of alcohol. A challenge for practitioners and researchers is to become mindful of the connection between oral cancer and alcoholic cirrhosis. Earlier studies exploring these relationships and potential mechanisms are discussed.
Perkins
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Department of Pediatric Dentistry, Louisiana State University, School of Dentistry, New Orleans, Louisiana, USA.
Perkins
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D000079:Acetaldehyde / Q000009:adverse effects; D000328:Adult; D000437:Alcoholism / Q000150:complications*; D044383:Black People; D002273:Carcinogens / Q000009:adverse effects; D000431:Ethanol / Q000009:adverse effects; D005260:Female; D022781:Hepatocytes / Q000187:drug effects; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000209:etiology* / Q000503:physiopathology; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D015996:Survival Rate
D002273:Carcinogens; D000431:Ethanol; D000079:Acetaldehyde