Ethics of clinical research in the developing world.
Many commentators believe that all clinical-trial participants must receive a level of care equivalent to the world's best. Using HIV/AIDS research as an example, we show how this 'Uniform Care Requirement' can undermine biomedical research aimed at improving global health, and then we point towards a more rational and balanced approach to ethical assessment.
Killen
Jack
J
National Institutes of Health, 9000 Rockville Pike, Bethesda, 20892 Maryland, USA. jkillen@niaid.nih.gov
Grady
Christine
C
Folkers
Gregory K
GK
Fauci
Anthony S
AS
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D023241:Antiretroviral Therapy, Highly Active; D002986:Clinical Trials as Topic; D003906:Developing Countries; D004992:Ethics, Medical; D006801:Humans