title: A role for antigen in the maintenance of immunological memory.
abstract: The immune system has a memory that it exhibits in the enhanced and augmented responses the second time it meets an antigen. The memory is the result of a number of changes to the system brought about during the primary response. The most important of these changes is the formation of an expanded pool of antigen-specific memory cells. One of the enduring questions in immunology is how these memory cells are maintained for such long periods.
authors.affiliation: Institute of Cell, Animal and Population Biology, University of Edinburgh, Ashworth Laboratories, UK. d.gray@ed.ac.uk
authors.forename: David
authors.initials: D
authors.lastname: Gray
mesh_terms: D000818:Animals; D000941:Antigens; D002470:Cell Survival; D006706:Homeostasis; D006801:Humans; D007156:Immunologic Memory; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology; D018448:Models, Immunological; D014611:Vaccination
chemical_list: D000941:Antigens