[Pyrethroid exposure following indoor treatments with a dog flea powder].
Pyrethroid exposure following indoor treatments with a dog flea powder.


METHODS
A 42 year old woman reported hair loss, gastrointestinal and non-specific symptoms. The patient has lived in a council flat and kept a dog who had been regularly treated with pyrethroid containing flea powder.


METHODS
The biological monitoring of pyrethroid meta-bolites in urine was performed using gas chromatography-mass spectrometry. The values at admission and follow-up after 4 weeks were highly elevated. Inspection of the flat revealed a humid and cramped dwelling.


METHODS
We recommended redevelopment and cleaning of the dwelling and the avoidance of ectoparasiticide use.


CONCLUSIONS
To our knowledge this is the first documented case of high indoor pyrethroid exposure following the use of ectoparasiticides with domestic animals. Pyrethroids can cause neurotoxic symptoms and skin irritation. There are few data concerning chronic effects. The causal connection between pyrethroid exposure and symptoms remains unclear and poses a great problem in environmental medicine.
Schulze
M
M
Umweltmedizinisches Zentrum, Klinikum Augsburg, Germany. umweltmedizin@klinikum-augsburg.de
Helber
B
B
Hardt
J
J
Ehret
W
W
D000328:Adult; D016902:Air Pollution, Indoor / Q000009:adverse effects* / Q000032:analysis; D000506:Alopecia Areata / Q000139:chemically induced* / Q000652:urine; D000818:Animals; D003937:Diagnosis, Differential; D004285:Dogs / Q000469:parasitology*; D004784:Environmental Monitoring; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced* / Q000652:urine; D006801:Humans; D026023:Permethrin / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D005423:Siphonaptera
D026023:Permethrin