title: Distemper outbreak and its effect on African wild dog conservation.
abstract: In December 2000, an infectious disease spread through a captive breeding group of African wild dogs (Lycaon pictus) in Tanzania, killing 49 of 52 animals within 2 months. The causative agent was identified as Canine distemper virus (CDV) by means of histologic examination, virus isolation, reverse transcriptase-polymerase chain reaction analysis, and nucleotide sequencing. This report emphasizes the importance of adequate protection against infectious diseases for the successful outcome of captive breeding programs of endangered species.
authors.affiliation: Seal Rehabilitation and Research Centre, Pieterburen, The Netherlands.
authors.forename: Marco W G
authors.initials: MW
authors.lastname: van de Bildt
authors.forename: Thijs
authors.initials: T
authors.lastname: Kuiken
authors.forename: Aart M
authors.initials: AM
authors.lastname: Visee
authors.forename: Sangito
authors.initials: S
authors.lastname: Lema
authors.forename: Tony R
authors.initials: TR
authors.lastname: Fitzjohn
authors.forename: Albert D M E
authors.initials: AD
authors.lastname: Osterhaus
mesh_terms: D000818:Animals; D000835:Animals, Wild / Q000821:virology; D004196:Disease Outbreaks / Q000517:prevention & control; D004216:Distemper / Q000401:mortality* / Q000517:prevention & control*; D004217:Distemper Virus, Canine / Q000302:isolation & purification*; D004285:Dogs; D006078:Government Programs; D013636:Tanzania; D014765:Viral Vaccines / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014765:Viral Vaccines