Influence of antisperm antibodies on T cell adhesion to extracellular matrix proteins in women with a history of unexplained infertility.
beta 1 integrins, receptors responsible for the binding of extracellular matrix proteins, mediate activation, adhesion, migration and differentiation in different tissue compartments. It has been recently demonstrated that integrins are distributed on sperm surface and on T cells, as well. The aim of this study was to establish influence of antisperm antibodies on T cell adhesion to extracellular matrix proteins in women with a history of unexplained infertility.
Jerzak
M
M
Laboratory of Reproductive Immunology, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Rechberger
T
T
Baranowski
W
W
Semczuk
M
M
Górski
A
A
D000328:Adult; D000917:Antibody Formation; D015703:Antigens, CD / Q000276:immunology; D016022:Case-Control Studies; D002448:Cell Adhesion / Q000276:immunology; D024141:Collagen Type IV / Q000276:immunology; D004549:Elastin / Q000276:immunology; D016326:Extracellular Matrix Proteins / Q000276:immunology*; D005260:Female; D005353:Fibronectins / Q000276:immunology; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000276:immunology*; D016023:Integrins / Q000276:immunology*; D008297:Male; D010835:Phytohemagglutinins / Q000378:metabolism; D011247:Pregnancy; D013094:Spermatozoa / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D013755:Tetradecanoylphorbol Acetate / Q000378:metabolism
D015703:Antigens, CD; D024141:Collagen Type IV; D016326:Extracellular Matrix Proteins; D005353:Fibronectins; D016023:Integrins; D010835:Phytohemagglutinins; D004549:Elastin; D013755:Tetradecanoylphorbol Acetate