Identification of human herpesvirus 6 latency-associated transcripts.
Four kinds of latency-associated transcripts of human herpesvirus 6 were identified which were detected only in latently infected cells. Although they were oriented in the same direction as the immediate-early 1 and 2 (IE1/IE2) genes and shared their protein-coding region with IE1/IE2, their transcription start sites and exon(s) were latency associated.
Kondo
Kazuhiro
K
Department of Microbiology, Osaka University Medical School, Suita-City, Osaka 565-0871, Japan. kkondo@micro.med.osaka-u.ac.jp
Shimada
Kazuya
K
Sashihara
Junji
J
Tanaka-Taya
Keiko
K
Yamanishi
Koichi
K
D002460:Cell Line; D002478:Cells, Cultured; D015654:Herpesvirus 6, Human / Q000502:physiology*; D006801:Humans; D017874:Immediate-Early Proteins / Q000235:genetics* / Q000378:metabolism; D008264:Macrophages / Q000821:virology; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000378:metabolism; D014158:Transcription, Genetic; D017735:Virus Latency
D017874:Immediate-Early Proteins; D012333:RNA, Messenger