Synthesis of a potential tetrasaccharide ligand for E-selectin.
A potential tetrasaccharide ligand for E-selectin, (Na(+-)O(3)SO-3)Galbeta-(1-->4)[Fucalpha-(1-->3)]Glcbeta-(1-->6)Gal, an analogue of the ovarian cystadenoma glycoprotein tetrasaccharide fragment, was synthesized in a highly practical way.
Qin
Zhi Hui
ZH
National Research Laboratory of Natural and Biomimetic Drugs, Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100083, PR China.
Liu
Hong
H
Li
Hui
H
Cai
Meng Shen
MS
Li
Zhong Jun
ZJ
D001665:Binding Sites; D019040:E-Selectin / Q000378:metabolism*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000378:metabolism
D019040:E-Selectin; D008024:Ligands; D009844:Oligosaccharides