title: Neurological outcome and quality of life after stroke due to vertebral artery dissection.
abstract: BACKGROUND
  Vertebral artery dissection is a well-recognized cause of posterior circulation stroke for which there is relatively little information on long-term outcomes. Quality of life (QOL) is an important patient-centred outcome measure.
  
  
  METHODS
  Stroke due to vertebral artery dissection was conservatively defined by neuroimaging documentation. Thirty sequential cases were identified based on a retrospective database and chart review with prospective follow-up. Surviving patients completed the Short Form-36 (SF-36) and the Stroke-Specific Quality of Life (SSQOL) scales and were subsequently examined neurologically and scored on the National Institutes of Health Stroke Scale (NIHSS). Comparisons were made between outcome on the stroke scale and QOL scales and between outcome on the SF-36 and the Canadian population.
  
  
  RESULTS
  There was discordance between outcomes recorded on a standard stroke scale and QOL measures with more patients scoring poorly on QOL measures. QOL was low in one third of the survivors. Overall QOL was significantly lower than the general population.
  
  
  CONCLUSIONS
  Stroke due to vertebral artery dissection results in poorer outcomes on patient-centred QOL measures than on a standard stroke scale.
authors.affiliation: Department of Clinical Neurosciences, University of Calgary, Foothills Hospital, Alta., Canada.
authors.forename: Diana
authors.initials: D
authors.lastname: Czechowsky
authors.forename: Michael D
authors.initials: MD
authors.lastname: Hill
mesh_terms: D000328:Adult; D000368:Aged; D002533:Cerebral Angiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011788:Quality of Life; D012008:Recurrence; D012720:Severity of Illness Index; D020521:Stroke / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality; D016019:Survival Analysis; D020217:Vertebral Artery Dissection / Q000150:complications* / Q000175:diagnosis / Q000401:mortality