[Retention of a memory trace of learning induced by a new and extinctive stimulus in C57BL/6J and BALB/c mice].
Influence of preliminary habituation to the experimental box on passive avoidance learning was studied in mice of C57BL/6J and BALB/c strains. The 20-fold preexposure of mice to the environmental stimulus inhibited the acquisition and consequent retention of a memory trace in BALB/c mice and did not affect the acquisition in C57BL/6J mice. Subsequent retention in this strain was facilitated. The interstrain differences are discussed with respect to detected genetically determined types of behavior and exstinctive inhibition at the habituation stage.
Dubrovina
N I
NI
Institute of Physiology, Siberian Division, Russian Academy of Medical Sciences, Novosibirsk.
Loskutova
L V
LV
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D003214:Conditioning, Classical / Q000502:physiology*; D004924:Escape Reaction / Q000502:physiology; D005108:Extinction, Psychological / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013045:Species Specificity