Balancing acts: respiratory sensations, motor control and human posture.
1. The present brief review covers some novel aspects of integration between respiration and movement of the body. 2. There are potent viscerosomatic reflexes in animals involving small-diameter pulmonary afferents that, when excited, would limit exercise. However, recent studies using lobeline injections to excite pulmonary afferents in awake humans suggest that there is no evoked reflex motoneuronal inhibition. Instead, the noxious respiratory sensations generated by the vagal afferents may be crucial in the decision to stop exercise. 3. While respiratory movements may affect limb movements, the control of the trunk and limbs can involve interaction (and even interference) with key respiratory muscles, such as the diaphragm. Recent studies have revealed that not only does the diaphragm receive feed-forward drive prior to some limb movements, but that it also contracts both phasically and tonically during repetitive limb movements. 4. Thus, challenges to posture can indirectly challenge ventilation, while coordinated diaphragm contraction may contribute to control of the trunk.
Gandevia
S C
SC
Prince of Wales Medical Research Institute, Sydney, Randwick, New South Wales, Australia. S.Gandevia@unsw.edu.au
Butler
J E
JE
Hodges
P W
PW
Taylor
J L
JL
D006801:Humans; D009046:Motor Neurons / Q000502:physiology*; D004856:Postural Balance / Q000502:physiology*; D011187:Posture / Q000502:physiology*; D012119:Respiration