title: Ethics of clinical research in the developing world.
abstract: Many commentators believe that all clinical-trial participants must receive a level of care equivalent to the world's best. Using HIV/AIDS research as an example, we show how this 'Uniform Care Requirement' can undermine biomedical research aimed at improving global health, and then we point towards a more rational and balanced approach to ethical assessment.
authors.affiliation: National Institutes of Health, 9000 Rockville Pike, Bethesda, 20892 Maryland, USA. jkillen@niaid.nih.gov
authors.forename: Jack
authors.initials: J
authors.lastname: Killen
authors.forename: Christine
authors.initials: C
authors.lastname: Grady
authors.forename: Gregory K
authors.initials: GK
authors.lastname: Folkers
authors.forename: Anthony S
authors.initials: AS
authors.lastname: Fauci
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D023241:Antiretroviral Therapy, Highly Active; D002986:Clinical Trials as Topic; D003906:Developing Countries; D004992:Ethics, Medical; D006801:Humans