title: Temporal sequence of response to unilateral GPi pallidotomy of motor symptoms in Parkinson's disease.
abstract: The present study was performed to determine the temporal sequence of the response to unilateral MRI/microelectrode-guided pallidotomy of each cardinal symptom in Parkinson's disease (PD). For this purpose, we performed a quantitative assessment of motor functions in 19 patients with PD at several time points up to 6 months following surgery. We here report that although all the motor signs were significantly improved 6 months after pallidotomy, the temporal sequence of tremor response was different from those of other symptoms.
authors.affiliation: Department of Neurosurgery, Kumamoto University Medical School, Kumamoto, Japan. sgoto@kaiju.medic.kumamoto-u.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Goto
authors.forename: T
authors.initials: T
authors.lastname: Hamasaki
authors.forename: S
authors.initials: S
authors.lastname: Nishikawa
authors.forename: A
authors.initials: A
authors.lastname: Okamura
authors.forename: M
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: N
authors.initials: N
authors.lastname: Soyama
authors.forename: S
authors.initials: S
authors.lastname: Mita
authors.forename: Y
authors.initials: Y
authors.lastname: Ushio
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D004599:Electric Stimulation Therapy / Q000379:methods; D005260:Female; D005917:Globus Pallidus / Q000502:physiology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008839:Microelectrodes; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D019957:Motor Skills Disorders / Q000503:physiopathology / Q000601:surgery; D010300:Parkinson Disease / Q000503:physiopathology* / Q000601:surgery*; D013997:Time Factors