Resonance Rayleigh scattering technology as a new method for the determination of the inclusion constant of beta-cyclodextrin.
The interaction of procaine hydrochloride and beta-cyclodextrin in aqueous solution was studied using resonance Rayleigh scattering technology. The molar ratio of the inclusion complex was 1:1 established by spectrophotometry. The resonance Rayleigh scattering technology was first applied in the determination of the beta-cyclodextrin inclusion constant. The inclusion constant of procaine hydrochloride beta-cyclodextrin complex Kf is 1.23 x 10(2) and 1.27 x 10(2) l mol(-1) for method I and 1.15 x 10(2) and 1.21 x 10(2) l mol(-1) for method II. These determination results were in correspondence with the results of the spectrophotometric and fluorescence methods. Therefore, the resonance Rayleigh scattering method can be used as a new technology for the determination of the inclusion constant.
Li
Nianbing
N
Institute of Environmental Chemistry, Southwest China Normal University, Chongqing, People's Republic of China. linb@swnu.edu.cn
Luo
Hongqun
H
Liu
Shaopu
S
Chen
Guonan
G
D003505:Cyclodextrins / Q000032:analysis / Q000737:chemistry*; D007700:Kinetics; D008956:Models, Chemical; D012542:Scattering, Radiation; D013050:Spectrometry, Fluorescence / Q000379:methods*; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D047392:beta-Cyclodextrins; C031215:betadex