A concise, modular synthesis of chiral peraza-macrocycles using chiral aziridines.
[reaction: see text] Novel chiral peraza-macrocycles were synthesized from chiral aziridines as a common building block. Efficient syntheses of chiral [26]-N(6), [12]-N(4), [9]-N(3), and [14]-N(4) systems were accomplished.
Kim
B Moon
BM
Center for Molecular Catalysis, School of Chemistry and Molecular Engineering, Seoul National University, Seoul 151-747, Korea. kimbm@snu.ac.kr
So
Soon Mog
SM
Choi
Hye Jin
HJ