La Crosse virus: replication in vertebrate and invertebrate hosts.
La Crosse virus is maintained in a cycle involving mosquitoes and small mammals. Vertebrate cell infection is generally cytolytic; vector cell infection results in persistent infection. Features of La Crosse virus replication that may permit the virus to traffic between vector and vertebrate hosts and condition different infection outcomes are described.
Borucki
Monica K
MK
USDA, Agricultural Research Service, Animal Disease Research Unit, 3003 ADBF, Washington State University, Pullman, Washington 99164, USA.
Kempf
Brian J
BJ
Blitvich
Bradley J
BJ
Blair
Carol D
CD
Beaty
Barry J
BJ
D000330:Aedes / Q000254:growth & development / Q000821:virology; D000595:Amino Acid Sequence; D000818:Animals; D009033:Culicidae / Q000821:virology*; D018562:Disease Transmission, Infectious; D004670:Encephalitis, California / Q000635:transmission; D006790:Host-Parasite Interactions; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D018062:La Crosse virus / Q000235:genetics* / Q000254:growth & development*; D008322:Mammals / Q000821:virology*; D051379:Mice; D008957:Models, Genetic; D014779:Virus Replication