A radical scavenging farnesylhydroquinone from a marine-derived fungus Penicillium sp.
Farnesylhydroquinone (1) has been isolated from the mycelium of a marine-derived fungus of the genus Penicillium. The structure of the compound (1) has been elucidated by spectral method. The compound 1 exhibits potent radical scavenging activity (IC50 12.5 microM) against the DPPH.
Son
Byeng Wha
BW
Department of Chemistry, Pukyong National University, Busan, Korea. sonbw@pknu.ac.kr
Kim
Jung Chul
JC
Choi
Hong Dae
HD
Kang
Jung Sook
JS
D001713:Biphenyl Compounds; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification; D005609:Free Radicals / Q000737:chemistry; D006873:Hydroquinones / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D016877:Oxidants / Q000737:chemistry; D010407:Penicillium / Q000737:chemistry*; D010851:Picrates / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D006873:Hydroquinones; D016877:Oxidants; D010851:Picrates; C464535:farnesylhydroquinone; C004931:1,1-diphenyl-2-picrylhydrazyl