Linkage analysis in a large family with primary pulmonary hypertension: genetic heterogeneity and a second primary pulmonary hypertension locus on 2q31-32.
Janssen
Bart
B
Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany. Bart_Janssen@med.uni-heidelberg.de
Rindermann
Matthias
M
Barth
Ulrike
U
Miltenberger-Miltenyi
Gabriel
G
Mereles
Derliz
D
Abushi
Adel
A
Seeger
Werner
W
Kübler
Wolfgang
W
Bartram
Claus R
CR
Grünig
Ekkehard
E
D055396:Bone Morphogenetic Protein 2; D052006:Bone Morphogenetic Protein Receptors, Type II; D019485:Bone Morphogenetic Proteins / Q000235:genetics; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D015150:Echocardiography, Doppler; D025401:Echocardiography, Stress; D018740:Genetic Heterogeneity; D008040:Genetic Linkage; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000235:genetics*; D008126:Lod Score; D009154:Mutation; D010375:Pedigree; D017346:Protein Serine-Threonine Kinases / Q000235:genetics; D016212:Transforming Growth Factor beta
C525718:BMP2 protein, human; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D016212:Transforming Growth Factor beta; D017346:Protein Serine-Threonine Kinases; C498218:BMPR2 protein, human; D052006:Bone Morphogenetic Protein Receptors, Type II