title: Attitudes toward genetic testing in patients with colorectal cancer.
abstract: OBJECTIVE
  The purpose of this study was to examine risk perceptions and interest in genetic testing among African American and White patients with colorectal cancer.
  
  
  METHODS
  In this cross-sectional study, 98 patients with colorectal cancer participated in a brief structured telephone interview. Information was collected on knowledge and risk perceptions regarding colorectal cancer genetics, health behaviors, knowledge about the availability of genetic testing, and interest in genetic testing for colorectal cancer susceptibility.
  
  
  RESULTS
  Sixty-one percent of the participants were worried about their relatives' risk of colorectal cancer, and 64% were concerned about being a colorectal cancer susceptibility gene carrier. Although 81% of the participants reported that they had never heard about a genetic test for colorectal cancer susceptibility, 72% stated that they would want to take the test if it were available. Predictors of intention to have a genetic test were younger age, less advanced stage of disease, and more frequent thoughts about colorectal cancer being hereditary.
  
  
  CONCLUSIONS
  These results suggest that the demand for genetic testing may be great, despite a general lack of knowledge about colorectal cancer genetics and the potential risks and limitations of testing. Education and counseling about cancer genetics and genetic testing may clarify misconceptions about hereditary colorectal cancer and help patients with colorectal cancer and their family members make informed decisions about whether to undergo testing.
authors.affiliation: University of Utah College of Nursing, 10 South, 2000 East Front Street, Salt Lake City, UT 84112, USA.
authors.forename: A Y
authors.initials: AY
authors.lastname: Kinney
authors.forename: Y A
authors.initials: YA
authors.lastname: Choi
authors.forename: B
authors.initials: B
authors.lastname: DeVellis
authors.forename: R
authors.initials: R
authors.lastname: Millikan
authors.forename: E
authors.initials: E
authors.lastname: Kobetz
authors.forename: R S
authors.initials: RS
authors.lastname: Sandler
mesh_terms: D000328:Adult; D001741:Black or African American / Q000193:education / Q000523:psychology*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health / Q000208:ethnology*; D015179:Colorectal Neoplasms / Q000208:ethnology / Q000235:genetics* / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics / Q000523:psychology; D005820:Genetic Testing / Q000523:psychology* / Q000592:standards*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009657:North Carolina; D010353:Patient Education as Topic; D011237:Predictive Value of Tests; D012307:Risk Factors; D011795:Surveys and Questionnaires; D044465:White People / Q000193:education / Q000523:psychology*