Synchronous benign and malignant salivary gland tumors in ipsilateral glands: a report of two cases and a review of literature.
BACKGROUND
Ipsilateral salivary gland tumors of different histologic types are rare and make up less than 0.3% of all salivary gland neoplasms. Only nine cases of synchronous benign and malignant ipsilateral parotid gland tumors have been described in the literature.


METHODS
Two additional cases of synchronous benign and malignant neoplasms in the parotid gland are reported and discussed with a review of literature.


RESULTS
Our first case describes a pleomorphic adenoma and a salivary duct carcinoma, an entity not previously reported in the literature. The second case documents the most common benign and malignant ipsilateral parotid gland neoplasm reported in this case series, a Warthin's tumor and a mucoepidermoid carcinoma.


CONCLUSIONS
Synchronous salivary gland tumors exhibiting both benign and malignant components are uncommonly observed, with only nine cases published to date. We describe two additional cases of a synchronous benign and malignant ipsilateral parotid gland tumor.
Curry
Jonathan L
JL
Department of Pathology, Loyola University Medical Center, Loyola University Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA. jcurry3@luc.edu
Petruzzelli
Guy J
GJ
McClatchey
Kenneth D
KD
Lingen
Mark W
MW
D000235:Adenolymphoma / Q000473:pathology; D008949:Adenoma, Pleomorphic / Q000473:pathology; D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D018277:Carcinoma, Mucoepidermoid / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010307:Parotid Neoplasms / Q000473:pathology; D018987:Salivary Ducts; D012468:Salivary Gland Neoplasms / Q000473:pathology*