Nausea and vomiting of pregnancy. Evidence-based treatment algorithm.
OBJECTIVE
One of my patients suffers from a moderate-to-severe form of morning sickness. She responded only partially to doxylamine and pyridoxine (Dicletin), and I wish to try adding another medication. What should my priority be?


CONCLUSIONS
An algorithm used by Motherisk to manage thousands of patients takes a hierarchical approach to this condition. This approach is evidence based with regard to fetal safety as well as efficacy.
Levichek
Zina
Z
Hospital for Sick Children, Toronto, Ont.
Atanackovic
Gardana
G
Oepkes
Dick
D
Maltepe
Carolyn
C
Einarson
Adrienne
A
Magee
Laura
L
Koren
Gideon
G
D000328:Adult; D000465:Algorithms; D000932:Antiemetics / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D009325:Nausea / Q000209:etiology / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology / Q000628:therapy*; D014839:Vomiting / Q000209:etiology / Q000628:therapy*
D000932:Antiemetics