title: Clinical experience with heart valve homografts in Brazil.
abstract: The purpose of this paper is to describe the development and progress of the first heart valve homograft bank in Brazil as well as to report the 5-year clinical results. The bank was started in 1995 and employs modern techniques of cryopreservation. Organ procurement increased from 11 hearts in 1995 to 138 hearts in 2000. In the beginning of the experience, only 2 hospitals were using these valves, but this increased to 18 centers in 2000. Clinical experience at the major center includes 117 cases of the Ross procedure, 62 aortic homograft implantations, and 18 cases of mitral homografts. Five-year survival after the Ross procedure was 99.1%, and survival free from any kind of complication was 88.8%. No patients are on anticoagulants, and the incidence of thromboembolism was null. We conclude that auto- and homografts are probably the best alternative to aortic valve replacement for young patients in developing countries.
authors.affiliation: Santa Casa de Misericórdia de Curitiba, Pontifícia Universidade Católica do Paraná, Brazil.
authors.forename: F D
authors.initials: FD
authors.lastname: da Costa
authors.forename: M B
authors.initials: MB
authors.lastname: da Costa
authors.forename: I A
authors.initials: IA
authors.lastname: da Costa
authors.forename: R
authors.initials: R
authors.lastname: Poffo
authors.forename: E A
authors.initials: EA
authors.lastname: Sardeto
authors.forename: E
authors.initials: E
authors.lastname: Matte
mesh_terms: D000293:Adolescent; D000328:Adult; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006351:Heart Valves; D006801:Humans; D008297:Male; D008875:Middle Aged; D014015:Tissue Banks / Q000458:organization & administration; D014184:Transplantation, Homologous