Clinical study on 53 cases of cadaveric kidney transplantation at Osaka City University Hospital.
BACKGROUND
In this study, we examined the effects of nonimmunological factors on cadaver kidney transplant.


METHODS
Fifty-three cadaver kidney transplant recipients were studied. They were divided into two groups, Group I ( donor age<60, n=38 ) and Group II ( donor age > or = 60, n=15). These patients were studied to determine whether donor age and recipient Body Mass Index (BMI) affected transplant outcome.


RESULTS
The 3 and 5-year overall graft / patient survival was 80.6 / 100% and 72.7 97.3%, respectively. The best S-Cr after transplantation was significantly (p<0.05) lower in Group I compared to Group II. The 1, 5 and 8-year graft survival was significantly (p<0.05) better in Group I. In the low BMI patients of Group II, 5-year graft survival was significantly (p<0.01) better than high BMI patients.


CONCLUSIONS
An aged cadaver donor was a risk factor for decreased posttransplant renal functions and lower graft survival. However, if a recipient with a low BMI can be selected, the outcome of cadaver kidney transplants from aged donors may be improved.
Nakatani
T
T
Department of Urology, Osaka City University, Graduate School of Medicine, Osaka, Japan. nakatani@msic.med.osaka-cu.ac.jp
Kim
T
T
Uchida
J
J
Kumada
N
N
Tsuchida
K
K
Takemoto
Y
Y
Yamamoto
K
K
Kishimoto
T
T
D000328:Adult; D015992:Body Mass Index; D002102:Cadaver; D006084:Graft Rejection; D006085:Graft Survival; D006785:Hospitals, University; D006801:Humans; D016030:Kidney Transplantation / Q000401:mortality