Statistical gene mapping of traits in humans--hypertension as a complex trait: is it amenable to genetic analysis?
Gene mapping refers to the localization of disease genes on the human gene map. The currently used mathematical methods for gene mapping are outlined and compared. The example of Gilles de la Tourette syndrome is discussed in detail.
Nothnagel
Michael
M
Laboratory of Statistical Genetics, Rockefeller University, New York, NY 10021-6399, USA.
Ott
Jürg
J
D002874:Chromosome Mapping / Q000379:methods* / Q000706:statistics & numerical data; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D006973:Hypertension / Q000235:genetics; D008957:Models, Genetic; D016571:Neural Networks, Computer; D005879:Tourette Syndrome / Q000235:genetics
D005819:Genetic Markers