Gastric adenocarcinoma in a patient re-infected with H. pylori after regression of MALT lymphoma with successful anti-H. pylori therapy and gastric resection: a case report.
BACKGROUND
Helicobacter pylori (H. pylori) has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patients with H. pylori infection.


METHODS
We report a patient with PGL in whom the tumor regressed after surgical resection combined with eradication of H. pylori infection. However, he developed GC on follow up; this was temporally associated with recrudescence/re-infection of H. pylori. This is perhaps first report of such occurrence.


CONCLUSIONS
Possible cause and effect relationship between H. pylori infection and both PGL and GC is discussed. This case also documents a unique problem in management of PGL in tropical countries where re-infection with H. pylori is supposed to be high.
Ghoshal
Uday C
UC
Department of Gastroenterology, Seth Sukhlal Karnani Memorial Hospital & Institute of Postgraduate Medical Education and Research, 244, AJC Bose Road, Kolkata 700020, India. ghoshal@sgpgi.ac.in
Guha
Debashish
D
Bandyopadhyay
Santu
S
Pal
Chiranjib
C
Chakraborty
Srikanta
S
Ghoshal
Ujjala
U
Ghosh
Tamal K
TK
Pal
Bhaskar B
BB
Banerjee
Prabir K
PK
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005743:Gastrectomy; D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D008297:Male; D012008:Recurrence; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000209:etiology* / Q000473:pathology / Q000628:therapy
D000900:Anti-Bacterial Agents