Apolipoprotein E gender effects on cognitive performance in age-associated memory impairment.
Among 100 individuals with age-associated memory impairment (AAMI), APOE E4 carriers performed worse on memory. However, when subjects were considered by gender, this effect was only observed in females. APOE E4 may have a more robust cognitive influence on female than on male individuals with AAMI.
Bartrés-Faz
David
D
Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Catalunya, Spain. dbartres@psi.ub.es
Junqué
Carme
C
Moral
Pedro
P
López-Alomar
Antoni
A
Sánchez-Aldeguer
Josep
J
Clemente
Imma C
IC
D000368:Aged; D000375:Aging / Q000502:physiology*; D001057:Apolipoproteins E / Q000235:genetics*; D003071:Cognition / Q000502:physiology*; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000235:genetics* / Q000523:psychology*; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology; D012727:Sex Characteristics
D001057:Apolipoproteins E