title: [Comparison of the efficacy of two different iron supplements for anemia prevention in piglets].
abstract: In a randomized, confirmatory study performed between July and October 2000 the efficacy of two iron products in preventing iron deficiency anaemia was compared. A total of 102 newborn piglets from ten litters were treated intramuscularly with 200 mg iron as iron dextran per ml, or 200 mg iron as gleptoferron per ml. For true comparison, piglets within a litter of a sow were subdivided into pairs on the basis of birth weight (one pair of the two heaviest piglets, et cetera). Within a pair, treatment with the iron supplements was randomly allocated. One group of piglets was injected at an age of 1 day (experiment 1) and the other group of piglets was injected at an age of 3 days (experiment 2). The piglets were weighed and blood samples were taken at an age of 18 days (experiment 1) or at an age of 19 days (experiment 2). Average daily weight gain and haemoglobin concentrations of both treatment groups were compared. Both products were very effective in preventing anaemia. No significant differences could be found between the two formulations. It can be concluded that iron-dextran and gleptoferron can be used with similar effect for anaemia prevention in piglets.
authors.affiliation: Dierenarts, Registratie-afdeling, Eurovet Animal Health B.V., Postbus 179, 5530 AD Bladel. a.vermeer@eurovet-ah.com
authors.forename: J E M
authors.initials: JE
authors.lastname: Vermeer
authors.forename: A H C
authors.initials: AH
authors.lastname: Kuijpers
authors.forename: A R W
authors.initials: AR
authors.lastname: Elbers
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000517:prevention & control / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D001835:Body Weight / Q000187:drug effects; D004338:Drug Combinations; D005260:Female; D007273:Injections, Intramuscular / Q000662:veterinary; D007501:Iron / Q000008:administration & dosage* / Q000494:pharmacology; D007505:Iron-Dextran Complex / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D008297:Male; D013400:Sugar Acids / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D013552:Swine; D013553:Swine Diseases / Q000097:blood / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D004338:Drug Combinations; D013400:Sugar Acids; C037905:gleptoferron; D007505:Iron-Dextran Complex; D007501:Iron