title: Extranodal non-Hodgkin's lymphoma of the maxillofacial region: analysis of 88 consecutive cases.
abstract: Examination of the records of 88 consecutive patients with extranodal maxillofacial non-Hodgkin's lymphoma (ENHL) was undertaken. Each patient's complete record was reviewed. Males outnumbered females by 1.7:1. Age at diagnosis ranged from 22 to 94 years (median 60.0). Affected anatomic sites included: maxillary sinus (22), nasal cavity (8), maxilla (13), mandible (8), salivary glands (14), and other (23). The most common presenting symptom was a non-painful mass. Associated dental symptoms were present in 72 patients and included intraoral swelling, pain, and loose teeth. Treatment included chemotherapy and radiation with a follow-up of 1-25 years. Treatment trends indicate a shift towards multimodal therapy. Non-Hodgkin's lymphoma of the head and neck, if discovered early, has an excellent prognosis.
authors.affiliation: Ontario Cancer Institute/Princess Margaret Hospital,  Department of Oral Pathology, Faculty of Dentistry, University ofToronto, Ontario, Canada M5G-2M9.
authors.forename: W G
authors.initials: WG
authors.lastname: Maxymiw
authors.forename: M
authors.initials: M
authors.lastname: Goldstein
authors.forename: R E
authors.initials: RE
authors.lastname: Wood
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000453:epidemiology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology*; D008297:Male; D008339:Mandibular Neoplasms / Q000453:epidemiology; D008441:Maxillary Neoplasms / Q000453:epidemiology; D008444:Maxillary Sinus Neoplasms / Q000453:epidemiology; D008875:Middle Aged; D009669:Nose Neoplasms / Q000453:epidemiology; D009864:Ontario / Q000453:epidemiology; D011379:Prognosis; D012074:Remission Induction; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000453:epidemiology; D012737:Sex Factors; D016896:Treatment Outcome