title: [Systemic manifestations of chronic hepatitis C].
abstract: It's well known that hepatitis C virus (HCV) related chronic liver disease may be associated with various extra hepatic disorders. These manifestations can revealed the hepatic disease. We review the available data on the conditions and asses their clinical implications: vascular, cutaneous, articular, neurological or renal disorders. There is no correlation between these extra hepatic manifestations and the severity of liver disease. Several recent studies have established a strong link between HCV infection and essential mixed cryoglobulinemia but some other extra hepatic associations are just fortuitous. Others datas are necessary to better analyze these extra hepatic disorders and to offer the beneficial treatment of patients with chronic hepatitis C.
authors.affiliation: Service de médecine interne à l'EPS Habib Thameur de Tunis.
authors.forename: S
authors.initials: S
authors.lastname: Kochbati
authors.forename: F
authors.initials: F
authors.lastname: Boussema
authors.forename: A
authors.initials: A
authors.lastname: Kilani
authors.forename: G
authors.initials: G
authors.lastname: Ben Amor
authors.forename: F
authors.initials: F
authors.lastname: Ben Dahmen
authors.forename: N
authors.initials: N
authors.lastname: Khamassi
authors.forename: S
authors.initials: S
authors.lastname: Ben Rhouma
authors.forename: O
authors.initials: O
authors.lastname: Cherif
authors.forename: M M
authors.initials: MM
authors.lastname: Kchir
authors.forename: L
authors.initials: L
authors.lastname: Rokbani
mesh_terms: D003449:Cryoglobulinemia / Q000209:etiology*; D015673:Fatigue Syndrome, Chronic / Q000209:etiology; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D009422:Nervous System Diseases / Q000209:etiology; D012216:Rheumatic Diseases / Q000209:etiology; D012859:Sjogren's Syndrome / Q000209:etiology; D012871:Skin Diseases / Q000209:etiology*; D014652:Vascular Diseases / Q000209:etiology*