title: Chemotherapy-induced nausea and vomiting.
abstract: Nausea and vomiting (N&V) is among the most distressing side effects of chemotherapy, despite the development of more efficacious antiemetic agents. As many as 60% of patients who receive cancer chemotherapy experience some degree of N&V. However, the actual incidence is difficult to determine with accuracy because of the variety of drugs, doses, and health conditions of the patients who receive cancer treatments. This article examines the state of the science related to chemotherapy-induced nausea and vomiting and reviews both pharmacologic and behavioral strategies that have demonstrated efficacy in managing these distressing symptoms.
authors.affiliation: University of Pittsburgh School of Nursing, 3500 Victoria Street, Room 415, Victoria Building, Pittsburgh, PA 15261, USA. cbe100@pitt.edu
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Bender
authors.forename: Roxanne W
authors.initials: RW
authors.lastname: McDaniel
authors.forename: Kathleen
authors.initials: K
authors.lastname: Murphy-Ende
authors.forename: Mary
authors.initials: M
authors.lastname: Pickett
authors.forename: Cynthia N
authors.initials: CN
authors.lastname: Rittenberg
authors.forename: Miriam P
authors.initials: MP
authors.lastname: Rogers
authors.forename: Susan M
authors.initials: SM
authors.lastname: Schneider
authors.forename: Rowena N
authors.initials: RN
authors.lastname: Schwartz
mesh_terms: D000932:Antiemetics / Q000008:administration & dosage / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000529:Complementary Therapies / Q000379:methods; D006801:Humans; D009325:Nausea / Q000139:chemically induced* / Q000517:prevention & control* / Q000523:psychology; D012702:Serotonin Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D014839:Vomiting / Q000139:chemically induced* / Q000517:prevention & control* / Q000523:psychology
chemical_list: D000932:Antiemetics; D000970:Antineoplastic Agents; D012702:Serotonin Antagonists