title: [Prognosis of retinoblastoma. Report of 50 cases].
abstract: OBJECTIVE
  The aim of this study was to analyze the factors influencing the prognosis of retinoblastoma.
  
  
  METHODS
  In 50 children with retinoblastoma, 69 eyes were reviewed. All patients had a full ophthalmic examination, a B-scan ultrasound, a computerized tomography scan and a pediatric examination. We performed enucleation in 47 eyes (with a histopathological study), external beam irradiation in 16 eyes, curitherapy in 4 eyes, cryotherapy in 3 eyes, and adjuvant chemotherapy in 7 cases.
  
  
  RESULTS
  The global survival rate was 87.5%. The main aggravating factors were: the size of the tumor and the extraretinal involvement with extension within the chroid, the sclera, and the optic nerve.
  
  
  CONCLUSIONS
  The prognosis of retinoblastoma mainly depends on the extraretinal invasion.
authors.affiliation: Service du Pr S. Ayed, Institut Hédi Raïes d'Ophtalmologie de Tunis, Bab Saadoun, Tunis.
authors.forename: H
authors.initials: H
authors.lastname: Bouguila
authors.forename: I
authors.initials: I
authors.lastname: Malek
authors.forename: C
authors.initials: C
authors.lastname: Boujemâa
authors.forename: M
authors.initials: M
authors.lastname: Mouelhi
authors.forename: F
authors.initials: F
authors.lastname: Daghfous
authors.forename: L
authors.initials: L
authors.lastname: Nacef
authors.forename: S
authors.initials: S
authors.lastname: Ayed
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D019572:Retinal Neoplasms / Q000175:diagnosis / Q000401:mortality; D012175:Retinoblastoma / Q000175:diagnosis / Q000401:mortality; D012189:Retrospective Studies; D015996:Survival Rate