title: Development of fermentation process for rDNA products.
abstract: Fermentation process development for recombinant DNA-derived products is becoming increasingly important in the current commercial and regulatory framework. This article provides an overview of the current approach to process development, and the contribution of developmental data to final process validation is highlighted. Cited literature is restricted to between 1995 and 2001.
authors.affiliation: Cangene Corporation, 3403 American Drive, Misissauga, Ontario, L4V 1T4, Canada. doug_cossar@Cangene.com
authors.forename: D
authors.initials: D
authors.lastname: Cossar
mesh_terms: D001709:Biotechnology / Q000379:methods*; D004274:DNA, Recombinant / Q000096:biosynthesis*; D005285:Fermentation; D011994:Recombinant Proteins / Q000096:biosynthesis*; D015203:Reproducibility of Results
chemical_list: D004274:DNA, Recombinant; D011994:Recombinant Proteins