[CAAX peptidomimetics: their farnesyltransferase inhibition activity and antitumor effect].
Ohkanda
Junko
J
Department of Chemistry, Yale University, 225 Prospect St., New Haven, CT 06520, USA.
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000502:physiology; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D017209:Apoptosis; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D006801:Humans; D018716:Molecular Mimicry; D010455:Peptides / Q000737:chemistry*; D018631:ras Proteins
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D010455:Peptides; D019883:Alkyl and Aryl Transferases; C083291:geranylgeranyltransferase type-I; D051231:Farnesyltranstransferase; D018631:ras Proteins