Methotrexate treatment for refractory subacute cutaneous lupus erythematosus.
Methotrexate is beneficial in rheumatoid arthritis and has been used in small studies of patients with systemic lupus erythematosus. We describe a patient with severe subacute cutaneous lupus erythematosus refractory to therapy with antimalarials and corticosteroids. Treatment with methotrexate resulted in complete clearing of the skin lesions without any side effects.
Kuhn
Annegret
A
Department of Dermatology, Heinrich-Heine-University, Düsseldorf, Germany.
Specker
Christof
C
Ruzicka
Thomas
T
Lehmann
Percy
P
D000328:Adult; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000188:drug therapy* / Q000473:pathology; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use*
D003879:Dermatologic Agents; D008727:Methotrexate