title: A comparative study of oral lichen planus and leukoplakia in two Argentine populations.
abstract: Oral Lichen Planus and Leukoplakia are two precancerous lesions of great relevance in oral pathology. A total of 4183 patients from the National University of Córdoba (UNC) and 4838 patients from the University of Buenos Aires (UBA) who had been admitted to the corresponding Oral Pathology Departments were analyzed. Of the total number of patients, 476 corresponded to Lichen Planus cases and 418 to Leukoplakia cases. Of the 476 Lichen Planus cases, 330 came from UBA and 146 from UNC, whereas of the 418 cases of Leukoplakia, 284 came from UNC and 134 from UBA. These differences were statistically significant (p < 0.02). Distribution according to sex and age was similar for Lichen Planus and Leukoplakia patients from both Oral Pathology Departments. The association between diabetes and Lichen Planus was similar for both centers, 11.5% for UNC and 14% for UBA. Similarly, no differences were found in terms of the association with tobacco consumption and dental microtrauma. Twenty-two percent of UNC patients were smokers whereas only 11% of UBA patients were smokers. This finding could explain the larger amount of Leukoplakia in UNC. The differences in the incidence of Lichen Planus could be attributed to the fact that the Buenos Aires population is under greater stress and the higher incidence of Leukoplakia in UNC could be related to the smoking habits of this population.
authors.affiliation: Department of Clinical Pathology, Faculty of Dentistry, National University of Córdoba.
authors.forename: F L
authors.initials: FL
authors.lastname: Femopase
authors.forename: M V
authors.initials: MV
authors.lastname: Binagui
authors.forename: S
authors.initials: S
authors.lastname: López de Blanc
authors.forename: M
authors.initials: M
authors.lastname: Gandolfo
authors.forename: H E
authors.initials: HE
authors.lastname: Lanfranchi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001118:Argentina / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007972:Leukoplakia, Oral / Q000453:epidemiology / Q000209:etiology*; D017676:Lichen Planus, Oral / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012907:Smoking / Q000009:adverse effects; D013315:Stress, Psychological / Q000150:complications; D014504:Urban Health