title: Levels of thermostable direct hemolysin produced by Vibrio parahaemolyticus O3:K6 and other serovars grown anaerobically with the presence of a bile acid.
abstract: Twenty-three V. parahaemolyticus strains, including 12 pandemic O3:K6 strains, were examined for their growth and production of thermostable direct hemolysin (TDH) under an anaerobic culture condition with or without presence of a bile acid, taurocholic acid (TCA). Both bacterial growth and TDH production were markedly enhanced by TCA for a majority of the strains, but the scale of the TDH production was disproportionately greater than that of the corresponding growth for 14 strains. Such enhancement was, however, not specific to the pandemic strains.
authors.affiliation: Department of Bioscience, Graduate School of Science and Technology, Kobe University, Rokko-dai 1-1-I, Nada-ku, Kobe, 657-8501, Japan.
authors.forename: Ro
authors.initials: R
authors.lastname: Osawa
authors.forename: Eiji
authors.initials: E
authors.lastname: Arakawa
authors.forename: Tadayuki
authors.initials: T
authors.lastname: Okitsu
authors.forename: Shiro
authors.initials: S
authors.lastname: Yamai
authors.forename: Haruo
authors.initials: H
authors.lastname: Watanabe
mesh_terms: D000332:Aerobiosis; D001427:Bacterial Toxins / Q000096:biosynthesis*; D001647:Bile Acids and Salts; D003470:Culture Media; D016521:Electrophoresis, Gel, Pulsed-Field; D005516:Food Microbiology; D005838:Genotype; D006460:Hemolysin Proteins / Q000096:biosynthesis*; D006801:Humans; D007214:Indonesia; D007564:Japan; D007723:Korea; D012623:Seawater; D013656:Taurocholic Acid; D013785:Thailand; D014481:United States; D014735:Vibrio Infections / Q000382:microbiology; D014736:Vibrio parahaemolyticus / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*
chemical_list: D001427:Bacterial Toxins; D001647:Bile Acids and Salts; D003470:Culture Media; D006460:Hemolysin Proteins; C068489:thermostable direct hemolysin; D013656:Taurocholic Acid