title: Serum amyloid A and high-density lipoprotein cholesterol: serum markers of inflammation in sarcoidosis and other systemic disorders.
abstract: Hypocholesterolemia has been observed in several inflammatory diseases such as rheumatoid arthritis, myeloproliferative disorders, systemic lupus erythematosus and sarcoidosis. Serum amyloid A is an acute-phase reactant that is related to the high-density lipoprotein cholesterol. This review discusses the relationship between the activation of the cells of the monocyte-macrophage system, determined by the serum amyloid A levels, and the lipid metabolism, measured as alterations in plasma lipoprotein concentrations. The mechanisms of this association during acute inflammation are also discussed in this review.
authors.affiliation: Internal Medicine Service, Ciutat Sanitària i Universitària de Bellvitge, Consell de Cent 218, 08011 Barcelona, Spain. asalazar@csub.scs.es
authors.forename: A
authors.initials: A
authors.lastname: Salazar
authors.forename: X
authors.initials: X
authors.lastname: Pintó
authors.forename: J
authors.initials: J
authors.lastname: Mañá
mesh_terms: D001053:Apolipoproteins / Q000097:blood*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000276:immunology; D015415:Biomarkers; D008076:Cholesterol, HDL / Q000097:blood*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology; D009196:Myeloproliferative Disorders / Q000097:blood / Q000276:immunology; D012507:Sarcoidosis / Q000097:blood* / Q000276:immunology*; D000685:Serum Amyloid A Protein
chemical_list: D001053:Apolipoproteins; D015415:Biomarkers; D008076:Cholesterol, HDL; D000685:Serum Amyloid A Protein