Exploiting antibodies as catalysts: potential therapeutic applications.
In this review, we explore recent developments in the generation of catalytic antibodies and their potential in therapy.
Tellier
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FRE-CNRS n (degree). 2230 Biocatalyze, Faculté des Sciences et des Techniques, 2, rue de la Houssinière, BP 92208, 44322 Nantes, France. Charles.Tellier@chimbio.univ-nantes.fr
D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D017151:Antibodies, Catalytic / Q000737:chemistry / Q000276:immunology / Q000378:metabolism / Q000627:therapeutic use*; D000918:Antibody Specificity; D000937:Antigen-Antibody Reactions; D001323:Autoantibodies / Q000737:chemistry / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D001666:Binding Sites, Antibody; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D015195:Drug Design; D006241:Haptens / Q000276:immunology; D006801:Humans; D006860:Hydrogen Bonding; D007114:Immunization; D009369:Neoplasms / Q000628:therapy; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D014777:Virus Diseases / Q000628:therapy
D000888:Antibodies, Anti-Idiotypic; D017151:Antibodies, Catalytic; D001323:Autoantibodies; D006241:Haptens