Sulfasalazine for alopecia areata.
Sulfasalazine is used as a therapy for various autoimmune conditions, including psoriasis; its effectiveness is presumed to be the result of its immunomodulatory effects. We have treated patients with severe alopecia areata with sulfasalazine as part of our dermatology practice and have noticed cosmetically acceptable regrowth in 23% of patients in whom a response could be determined. In view of its good safety profile, sulfasalazine may be considered for systemic treatment of severe alopecia areata.
Ellis
Charles N
CN
Department of Dermatology, 1910 A. Alfred Taubman Center, University of Michigan Medical School, Ann Arbor, MI 48109-0314, USA.
Brown
Margaret F
MF
Voorhees
John J
JJ
D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy* / Q000235:genetics; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008875:Middle Aged; D012460:Sulfasalazine / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D012460:Sulfasalazine