title: Methotrexate treatment for refractory subacute cutaneous lupus erythematosus.
abstract: Methotrexate is beneficial in rheumatoid arthritis and has been used in small studies of patients with systemic lupus erythematosus. We describe a patient with severe subacute cutaneous lupus erythematosus refractory to therapy with antimalarials and corticosteroids. Treatment with methotrexate resulted in complete clearing of the skin lesions without any side effects.
authors.affiliation: Department of Dermatology, Heinrich-Heine-University, Düsseldorf, Germany.
authors.forename: Annegret
authors.initials: A
authors.lastname: Kuhn
authors.forename: Christof
authors.initials: C
authors.lastname: Specker
authors.forename: Thomas
authors.initials: T
authors.lastname: Ruzicka
authors.forename: Percy
authors.initials: P
authors.lastname: Lehmann
mesh_terms: D000328:Adult; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000188:drug therapy* / Q000473:pathology; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D003879:Dermatologic Agents; D008727:Methotrexate