Acute disseminated encephalomyelitis and poststreptococcal acute glomerulonephritis.
We experienced the case of a boy suffering from acute disseminated encephalomyelitis and concomitant acute glomerulonephritis. The multiple lesions observed on MR images, which located mainly in the cortical gray matter, quickly responded to methyl prednisolone pulse therapy. Renal biopsy confirmed the diagnosis of poststreptococcal acute glomerulonephritis. Streptococcus pyogenes was identified by pharyngeal culture, and the infection was serologically confirmed. We speculated that S. pyogenes infection was coincidentally involved in both diseases.
Ito
Shu-ichi
S
Department of Pediatrics, Yokohama City University Medical Center, 4-57, Urafune-cho, Minami-ku, 232-0024 Japan. sk-ito@tb3.so-net.ne.jp
Nezu
Atsuo
A
Matsumoto
Chizuru
C
Aihara
Yukoh
Y
Yokota
Shumpei
S
D000208:Acute Disease; D001706:Biopsy; D001921:Brain / Q000382:microbiology / Q000473:pathology; D002648:Child; D004673:Encephalomyelitis, Acute Disseminated / Q000382:microbiology* / Q000473:pathology; D005921:Glomerulonephritis / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D013290:Streptococcal Infections / Q000150:complications*; D013297:Streptococcus pyogenes / Q000302:isolation & purification