title: Pelvic organ prolapse: a review.
abstract: Pelvic organ prolapse is a common medical problem in parous women. This condition usually refers to a combination of deficiencies of the pelvic organs as they relate to support mechanisms of the vaginal wall. Symptoms vary--an accurate diagnosis requires a careful and complete physical examination with attention directed toward the pelvis and perineum. Although many patients will not require surgical treatment for pelvic organ prolapse, a comprehensive approach to repair in which all of the anatomic defects affecting support are addressed is necessary for successful treatment. Patients presenting with pelvic organ prolapse often provide some of the most complex, challenging, and rewarding cases in reconstructive pelvic surgery. This article addresses the definitions and classifications, prevalence and risk factors, and anatomy and pathophysiology relevant to pelvic organ prolapse. Discussion also includes diagnosis and approaches to management (surgical and nonsurgical) of anterior vaginal wall prolapse, cystourethrocele, apical vaginal prolapse, uterine prolapse and enterocele, posterior vaginal wall prolapse, rectocele, and pelvic floor relaxation and perineal laxity, with indications for and approaches to surgery, along with possible complications.
authors.affiliation: Division of Urology, Department of Surgery, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, Pa., USA. erovner@mail.med.upenn.edu
authors.forename: E S
authors.initials: ES
authors.lastname: Rovner
mesh_terms: D005260:Female; D013509:Gynecologic Surgical Procedures; D006547:Hernia / Q000175:diagnosis / Q000503:physiopathology; D059685:Herniorrhaphy; D006801:Humans; D017773:Pelvic Floor / Q000503:physiopathology / Q000601:surgery; D020047:Rectocele / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D014596:Uterine Prolapse / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D014621:Vagina / Q000503:physiopathology / Q000601:surgery