Effect of short-term feed restriction and refeeding on serum concentrations of leptin, luteinizing hormone and insulin in ovariectomized gilts.
Ovariectomized gilts were either placed on full feed (FF) or restricted to one-third of the full feed amount (RST) for 7 days. Blood samples were taken through jugular catheters every 15 min for 4 h at the end of the 7-day period. Then dietary treatments were reversed and 7 days later samples were taken as before. Serum concentrations of leptin, insulin and luteinizing hormone (LH) were determined by radioimmunoassay. LH pulse frequency and mean serum leptin and insulin concentrations were lower (P < 0.01) in RST than FF gilts. Reversal of treatment reversed the patterns of hormone secretion. These results confirm previous observations that feed restriction can inhibit pulsatile LH secretion and also decrease leptin and insulin secretion.
Whisnant
C S
CS
Department of Animal Science, North Carolina State University, P.O. Box 7621, Raleigh 27695, USA. scott_whisnant@ncsu.edu
Harrell
R J
RJ
D000818:Animals; D005260:Female; D005502:Food; D005508:Food Deprivation; D007328:Insulin / Q000097:blood*; D020738:Leptin / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood*; D010052:Ovariectomy; D010507:Periodicity; D013552:Swine / Q000097:blood*
D007328:Insulin; D020738:Leptin; D007986:Luteinizing Hormone