title: Skylab experiment M-171 "Metabolic Activity"--results of the first manned mission.
abstract: The experiment was performed to ascertain whether man's ability to perform mechanical work would be altered as a result of exposure to the weightless environment. Skylab II crewmen were exercised on a bicycle ergometer at loads approximating 25%, 50%, and 75% of their maximum oxygen uptake while their physiological responses were monitored. The results of these tests indicate that the crewmen had no significant decrement in their response to exercise during their exposure to zero gravity. Immediately postflight, however, all crewmen demonstrated an inability to perform the programmed exercise with the same metabolic effectiveness as they did both preflight and inflight. The most significant changes were elevated heart rates for the same work load and oxygen consumption (decreased oxygen pulse), decreased stroke volume, and decreased cardiac output at the same oxygen consumption level. It is apparent that the changes occurred inflight, but did not manifest themselves until the crewmen attempted to readapt to the 1-G environment.
authors.affiliation: Biomedical Research Division, NASA Johnson Space Center, Houston, Texas, USA.
authors.forename: E L
authors.initials: EL
authors.lastname: Michel
authors.forename: J A
authors.initials: JA
authors.lastname: Rummel
authors.forename: C F
authors.initials: CF
authors.lastname: Sawin
mesh_terms: D000222:Adaptation, Physiological; D000337:Aerospace Medicine; D001642:Bicycling; D001794:Blood Pressure / Q000502:physiology; D002245:Carbon Dioxide / Q000378:metabolism; D002302:Cardiac Output / Q000502:physiology; D016552:Ergometry / Q000295:instrumentation; D015444:Exercise / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology*; D005082:Physical Exertion; D013026:Space Flight / Q000295:instrumentation*; D014893:Weightlessness
chemical_list: D002245:Carbon Dioxide