Analysis of a circular code model.
A circular code has been identified in the protein (coding) genes of both eukaryotes and prokaryotes by using a statistical method called trinucleotide frequency (TF) method [Arquès & Michel (1996). J. theor. Biol. 182, 45-58]. Recently, a probabilistic model based on the nucleotide frequencies with a hypothesis of absence of correlation between successive bases on a DNA strand, has been proposed by Koch & Lehmann [(1997). J. theor. Biol. 189, 171-174] for constructing some particular circular codes. Their interesting method which we call here nucleotide frequency (NF) method, reveals several limits for constructing the circular code observed with protein genes.
Lacan
J
J
Laboratoire d'Informatique de Franche-Comté, Université de Franche-Comté, IUT de Belfort-Montbéliard, Montbéliard, France. jerome.lacan@pu-pm.univ-fcomte.fr
Michel
C J
CJ
D000818:Animals; D003198:Computer Simulation; D005787:Gene Frequency; D005815:Genetic Code; D008957:Models, Genetic; D011336:Probability; D011506:Proteins / Q000235:genetics*; D018911:Trinucleotide Repeats
D011506:Proteins