Five new chromones possessing monoamine oxidase inhibitory activity from an ascomycete, Chaetomium quadrangulatum.
Five novel chromones (1,4-benzopyran-4-ones), among which three are tetracyclic and one contains a sulfonyl group, have been isolated from an Ascomycete, Chaetomium quadrangulatum, as monoamine oxidase inhibitory features, and named chaetoquadrins A (1)-E (5).
Fujimoto
Haruhiro
H
Graduate School of Pharmaceutical Sciences, Chiba University, Japan. fujimoto@p.chiba-u.ac.jp
Nozawa
Masato
M
Okuyama
Emi
E
Ishibashi
Masami
M
D001203:Ascomycota / Q000737:chemistry*; D002867:Chromones / Q000737:chemistry / Q000494:pharmacology*; D002942:Circular Dichroism; D009682:Magnetic Resonance Spectroscopy; D008996:Monoamine Oxidase Inhibitors / Q000737:chemistry / Q000494:pharmacology*
D002867:Chromones; D008996:Monoamine Oxidase Inhibitors