title: Prevention of tumor spread by matrix metalloproteinase-9 inhibition: old drugs, new concept.
abstract: In the following review we will discuss some familiar drugs with potential use as adjuvant anti-neoplastic agents. We will highlight their unfamiliar property of being able to inhibit matrix metalloproteinase-9 activity, which has recently been proven to play a key role in cancer spread. These drugs' high-safety profile may allow clinicians to construct new anti-cancer protocols that may prove to be less toxic alternatives to those commonly used.
authors.affiliation: Department of Medicine 'B' and Research Center for Autoimmune Diseases, Sheba Medical Center (affiliated to the Sackler Faculty of Medicine, Tel-Aviv University), 52621, Tel-Hashomer, Israel
authors.forename: Shaul
authors.initials: S
authors.lastname: Lev
authors.forename: Boris
authors.initials: B
authors.lastname: Gilburd
authors.forename: Niza
authors.initials: N
authors.lastname: Lahat
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Shoenfeld