Type 4 pilus biogenesis and type II-mediated protein secretion by Vibrio cholerae occur independently of the TonB-facilitated proton motive force.
In Vibrio cholerae, elaboration of toxin-coregulated pilus and protein secretion by the extracellular protein secretion apparatus occurred in the absence of both TonB systems. In contrast, the cognate putative ATPases were required for each process and could not substitute for each other.
Bose
Niranjan
N
Department of Microbiology and Immunology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.
Payne
Shelley M
SM
Taylor
Ronald K
RK
D000251:Adenosine Triphosphatases / Q000502:physiology; D000255:Adenosine Triphosphate / Q000378:metabolism; D001426:Bacterial Proteins / Q000378:metabolism* / Q000502:physiology*; D010861:Fimbriae, Bacterial / Q000502:physiology*; D008565:Membrane Proteins / Q000502:physiology*; D018892:Proton-Motive Force; D014734:Vibrio cholerae / Q000502:physiology*
D001426:Bacterial Proteins; D008565:Membrane Proteins; C057616:tonB protein, Bacteria; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases