Turn formation initiated by a bissulfoximine motif: synthesis and structural investigation.
[reaction: see text] Bissulfoximines containing heterochiral SulfCO-SulfCO units may be used as molecular templates, which induce U-shaped conformations in peptidelike structures. The synthesis of such molecules has been investigated, and the structural requirements of this new turn motif have been identified.
Bolm
Carsten
C
Institut für Organische Chemie der RWTH Aachen, Professor-Pirlet-Str.1, D-52056 Aachen, Germany. carsten.bolm@oc.rwth-aachen.de
Müller
Dirk
D
Hackenberger
Christian P R
CP
D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation
D007097:Imines