title: The added value of transvaginal sonohysterography over transvaginal sonography alone in women with known or suspected leiomyoma.
abstract: OBJECTIVE
  To assess whether sonohysterography provides added diagnostic value over transvaginal sonography in patients with suspected or known myomas by comparing diagnostic confidence, interobserver agreement, accuracy, and change in diagnoses when 2 independent observers interpreted transvaginal sonography alone and later interpreted transvaginal sonography and sonohysterography together.
  
  
  METHODS
  Hard copy images from 72 women were interpreted independently by 2 sonologists on separate occasions, rating parameters (abnormal uterus, myoma in any location, submucous myoma, classification of location of a submucous myoma with respect to the uterine cavity, myoma remote from the cavity, adenomyosis, and focal and diffuse endometrial lesions) on a scale of 1 to 5 (1 indicated definitely no; 2, probably no; 3, uncertain; 4, probably yes; and 5, definitely yes). Correlation was made with clinical and imaging follow-up, surgery, and pathologic examination.
  
  
  RESULTS
  The added information provided by sonohysterography resulted in improved diagnostic confidence for most parameters. Interobserver agreement was markedly improved for the diagnosis and location of submucous myomas and focal endometrial lesions. Sensitivity values for submucous myomas and focal endometrial lesions were 100% and 90% for transvaginal sonography and sonohysterography together and 100% and 70% for transvaginal sonography alone.
  
  
  CONCLUSIONS
  We found that sonohysterography does provide additional information over transvaginal sonography alone and is an important adjunct to transvaginal sonography in symptomatic women with known or suspected myomas, particularly before surgical or medical therapy.
authors.affiliation: Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Becker
authors.forename: Anna S
authors.initials: AS
authors.lastname: Lev-Toaff
authors.forename: Emilia P
authors.initials: EP
authors.lastname: Kaufman
authors.forename: Ethan J
authors.initials: EJ
authors.lastname: Halpern
authors.forename: Maria Isabel
authors.initials: MI
authors.lastname: Edelweiss
authors.forename: Alfred B
authors.initials: AB
authors.lastname: Kurtz
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging* / Q000453:epidemiology; D015588:Observer Variation; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology; D014599:Uterus / Q000000981:diagnostic imaging