Patient acceptability of and tolerance to a placebo intravaginal ring in hysterectomized women: a pilot study.
OBJECTIVE
To assess the tolerance to and patient acceptability of a placebo intravaginal ring in hysterectomized, postmenopausal women over a 28-day period.


METHODS
Open, single-center.


METHODS
University hospital specialist menopause clinic.


METHODS
A total of 24 healthy postmenopausal women attending menopause clinics at King's College Hospital and the Amarant Centre, London.


METHODS
Discomfort, ring expulsions, bowel, urinary and sexual difficulties associated with the ring and women's overall views on this method.


RESULTS
The major problems with use of the intravaginal ring were patient discomfort, involuntary ring expulsion and sexual partner discomfort. These were experienced by 13, 11 and seven women and their partners, respectively, and resulted in premature discontinuation by three women who suffered discomfort and two women who experienced recurrent involuntary ring expulsion.


CONCLUSIONS
Two-thirds of the patients found the intravaginal ring acceptable, one-third did not.
Spencer
C P
CP
Menopause Clinic, King's College Hospital, London, UK.
Cooper
A J
AJ
Ross
D
D
Ptaszynska
T
T
Graham
J
J
Whitehead
M I
MI
D000282:Administration, Intravaginal; D000328:Adult; D000368:Aged; D003075:Coitus; D016503:Drug Delivery Systems / Q000295:instrumentation; D015914:Estrogen Replacement Therapy / Q000295:instrumentation*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010146:Pain; D017060:Patient Satisfaction; D010865:Pilot Projects; D010919:Placebos; D017698:Postmenopause; D014621:Vagina
D010919:Placebos