Intake and hedonics of calcium and sodium during pregnancy and lactation in the rat.
These experiments sought to distinguish whether increased calcium intake during pregnancy and lactation in the rat is due to arousal of a specific calcium appetite, with altered taste hedonics, as occurs with sodium depletion, to reduced taste sensitivity, or to the hyperdipsia of reproduction. We find that, during pregnancy and lactation, CaCl(2) intake is not increased more (in fact less) than intakes of control tastants, MgCl(2) and quinine HCl, and multiparous dams do not have a greater calcium intake than primaparous dams. Changes in taste reactivity to CaCl(2) and to NaCl do not correlate with changes in intake of these minerals during pregnancy or lactation, suggesting that alterations in hedonics or sensitivity do not explain the increased intake of these minerals. Taken together with the increased intake of all the tastants, it may be that the increased intakes of calcium and sodium during reproduction are not due to respective specific appetites or to a general mineral appetite but rather to the reproduction-increased ingestion that may meet all the dam's increased mineral and nutrient requirements. Differences in the degree of increased intakes of tastes may be due to specific alterations in their transduction during reproduction.
Leshem
M
M
Department of Psychology, University of Haifa, Haifa, 31905, Israel. micah.leshem@psy.haifa.ac.il
Levin
T
T
Schulkin
J
J
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D002136:Calcium, Dietary / Q000494:pharmacology*; D004326:Drinking / Q000502:physiology; D004435:Eating / Q000187:drug effects; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D007774:Lactation / Q000523:psychology*; D015636:Magnesium Chloride / Q000494:pharmacology; D010298:Parity / Q000502:physiology; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000523:psychology*; D011803:Quinine; D051381:Rats; D017207:Rats, Sprague-Dawley; D012982:Sodium, Dietary / Q000494:pharmacology*; D013395:Sucrose; D013649:Taste / Q000187:drug effects
D002136:Calcium, Dietary; D012982:Sodium, Dietary; D015636:Magnesium Chloride; D013395:Sucrose; D011803:Quinine