title: Massive septic thrombus formation on a superior vena cava indwelling catheter following Torulopsis (Candida) glabrata fungemia.
abstract: Fungal endocarditis is an exceedingly rare complication of indwelling central venous catheters in adults. Here we describe what appears to be the first case of a right atrial thrombus superinfected with the yeast Torulopsis (Candida) glabrata and attached to an indwelling superior vena cava catheter that was not used for parenteral nutrition. A large vegetation-like mass adherent to the catheter tip was visualized by transesophageal echocardiography in a patient who presented with signs of septic pulmonary embolism. Following open-heart surgery, the definitive diagnosis was established by histopathologic examination of the surgical specimen.
authors.forename: Monica T
authors.initials: MT
authors.lastname: Gressianu
authors.forename: Vivek N
authors.initials: VN
authors.lastname: Dhruva
authors.forename: Rohit R
authors.initials: RR
authors.lastname: Arora
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Patel
authors.forename: Santos
authors.initials: S
authors.lastname: Lopez
authors.forename: Ayad K
authors.initials: AK
authors.lastname: Jihayel
authors.forename: Muhamed
authors.initials: M
authors.lastname: Saric
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D017548:Echocardiography, Transesophageal; D004696:Endocarditis / Q000188:drug therapy / Q000209:etiology*; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D008875:Middle Aged; D013927:Thrombosis / Q000473:pathology*
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B