Isolation and phylogeny of endogenous retrovirus HERV-F family in Old World monkeys. Brief report.
A new human endogenous retroviral family (HERV-F) has recently been identified from human chromosome 7q31.1-q31.3 that was identical to the XA34 cDNA clone isolated from a human glioma cDNA library with an ERV-9 env probe. We investigated pol fragments of the HERV-F family from the Old World monkeys (crab-eating monkey, African green monkey, and baboon) and analyzed these with the HERV-F (Hu-XA34). Fifteen pol fragments of the HERV-F family were detected from the Old World monkeys. They showed a high degree of sequence similarity (81-99%) with that of the HERV-F (Hu-XA34). Phylogenetic analysis of pol fragments with those of the human genome distinctively showed five groups, indicating that HERV-F family could be amplified at least five times after the original integration into the monkey genome or represent integration events independently during primate evolution.
Kim
H S
HS
Division of Biological Sciences, College of Natural Sciences, Pusan National University, Korea. khs307@hyowon.cc.pusan.ac.kr
Hyun
B H
BH
Takenaka
O
O
D000595:Amino Acid Sequence; D000818:Animals; D016663:Cercopithecinae / Q000821:virology*; D002522:Chlorocebus aethiops / Q000821:virology; D020077:Endogenous Retroviruses / Q000235:genetics* / Q000302:isolation & purification*; D015684:Gene Products, pol / Q000235:genetics; D008252:Macaca fascicularis / Q000821:virology; D008969:Molecular Sequence Data; D010215:Papio / Q000821:virology; D010802:Phylogeny; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
D015684:Gene Products, pol