title: A clinical study evaluating a new chairside and take-home whitening system.
abstract: This study evaluated the efficacy of tooth color modifications with a 15% hydrogen peroxide in-office whitening system when applied for a 30-, 45-, or 60-minute period and combined with a 10% carbamide peroxide take-home system. Twenty-four patients participated in this randomized, parallel clinical evaluation. Six maxillary anterior teeth with a shade of A3 or darker were selected. Patients were randomly divided into 3 groups of 8: Group I patients received a 30-minute application, Group II received a 45-minute application, and Group III received a 60-minute application of the initial in-office treatment. All patients returned at 24 hours for shade evaluation and receipt of a whitening tray with a 10% carbamide peroxide for 7 consecutive days. Patients returned at 24 hours, 72 hours, and on the 8th day of take-home treatment for shade evaluation. Kruskal-Wallis ANOVA showed no statistically significant difference between the groups (P > .10) at completion of treatment. When all three groups were combined, a mean shade change > 8 was seen. No significant difference existed for tooth color modifications when varied application times of 30-, 45- or 60-minute in-office whitening with 15% hydrogen peroxide was used in combination with 10% carbamide peroxide take-home whitening.
authors.affiliation: Advanced Technology Center, Department of Restorative Dentistry, Tufts University School of Dentistry, Boston, Massachusetts, USA.
authors.forename: A
authors.initials: A
authors.lastname: Papathanasiou
authors.forename: D
authors.initials: D
authors.lastname: Bardwell
authors.forename: G
authors.initials: G
authors.lastname: Kugel
mesh_terms: D000704:Analysis of Variance; D000077463:Carbamide Peroxide; D003742:Dental Devices, Home Care; D003807:Dentin Sensitivity / Q000139:chemically induced; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage / Q000009:adverse effects; D015588:Observer Variation; D010545:Peroxides / Q000008:administration & dosage / Q000009:adverse effects; D014073:Tooth Bleaching / Q000009:adverse effects / Q000379:methods*; D014508:Urea / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D004338:Drug Combinations; D010545:Peroxides; D000077463:Carbamide Peroxide; D014508:Urea; D006861:Hydrogen Peroxide