title: Cervical intraepithelial dysplasia (CIN 3) and history of herpes genitalis (HSV2) in women living in Attica, Greece.
abstract: This article presents a study on women living in Attica, Greece (an area of 4.5 million inhabitants) who visited the outpatient clinics of two specialized hospitals for a follow-up for cervical intraepithelial neoplasia (CIN 3). A random sample of 170 women with CIN 3 and a control group of 195 women coming from the general population were interviewed. A semi-structured designed questionnaire was used as an instrument for data collection. The aim of the study was to search for a possible correlation between CIN 3 and a past history of herpes genitalis (HSV2) of the women and/or their partners. According to the results, CIN 3 is more frequent among women between 26 and 40 years of age. The majority of the patients (70.3%) reported a past history of HSV2, but only 10.9% of the subjects in the control group had the same medical history (p = 0.000). Sixteen percent of the patients and only 5.3% of the subjects in the control group reported infection of their sexual partners with HSV2. 75 patients (44.6%) stated that they did not know if their sexual partners had a past history of HSV2, while only 27 women (13.3%) in the control group reported the same (p = 0.000). Patients reported more sexual partners than women in the control group.
authors.affiliation: General Peripheral Hospital of Athens, Agios Savas Hospital, Athens, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Sapountzi-Krepia
authors.forename: Z
authors.initials: Z
authors.lastname: Roupa
authors.forename: S
authors.initials: S
authors.lastname: Binioris
authors.forename: M
authors.initials: M
authors.lastname: Tsirintani
authors.forename: S
authors.initials: S
authors.lastname: Darivakis
authors.forename: G
authors.initials: G
authors.lastname: Frangakis
authors.forename: M
authors.initials: M
authors.lastname: Gianniri
authors.forename: G
authors.initials: G
authors.lastname: Vamvakaris
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006115:Greece; D006558:Herpes Genitalis / Q000150:complications*; D018258:Herpesvirus 2, Human; D006801:Humans; D008875:Middle Aged; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000209:etiology*; D002578:Uterine Cervical Dysplasia / Q000209:etiology*