title: [Prenatal manifestation of a congenital glioblastoma - Case report].
abstract: In prenatal ultrasound screening, internal hydrocephalus and intracranial bleeding of the fetus are considered as primary diagnostic signs for a congenital brain tumor. We report the prenatal sonographic diagnosis of a congenital glioblastoma due to acute fetal internal hydrocephalus in the 37th week of gestation. After birth, the tumor's hyperechoic appearance on ultrasound was indistinguishable from intracranial bleeding. Diagnosis of a congenital glioblastoma (WHO stage IV) was confirmed by subtotal tumorectomy in the 9th week of life. In the international literature, only 6 cases of prenatally diagnosed glioblastomas have so far been reported, all of which associated with sonographically diagnosed fetal hydrocephalus. Further sonographic signs for a brain tumor are the tumor mass itself, a polyhydramnion, enlarged biparietal diameters and head circumferences, as well as suspected intracranial bleeding.
authors.affiliation: Universitätsfrauenklinik Ulm, Germany. sabine@schindelmann.de
authors.forename: S
authors.initials: S
authors.lastname: Schindelmann
authors.forename: G
authors.initials: G
authors.lastname: Sandner
authors.forename: N
authors.initials: N
authors.lastname: Harbeck
authors.forename: G
authors.initials: G
authors.lastname: Debus
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000151:congenital / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D005909:Glioblastoma / Q000151:congenital* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000601:surgery; D007223:Infant; D007231:Infant, Newborn; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D016216:Ultrasonography, Prenatal