Triptans in the treatment of basilar migraine and migraine with prolonged aura.
OBJECTIVE
To report on the use of triptans in migraine with prominent neurologic symptoms.


BACKGROUND
As stated in their package inserts, the triptans are contraindicated in patients with basilar or familial hemiplegic migraine, and physicians are reluctant to prescribe these drugs to other patients with prominent or prolonged aura.


METHODS
We evaluated 13 patients with basilar migraine, familial hemiplegic migraine, or migraine with prominent or prolonged aura who had received triptans.


RESULTS
Excellent; no adverse events.


CONCLUSIONS
The contraindication of triptans in basilar migraine should be reconsidered. Similarly, prominent or prolonged aura may not represent a reasonable contraindication to triptan therapy.
Klapper
J
J
Colorado Neurology and Headache Center, Denver, CO 80218, USA.
Mathew
N
N
Nett
R
R
D000293:Adolescent; D000328:Adult; D000075202:Contraindications; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy* / Q000235:genetics; D020325:Migraine with Aura / Q000188:drug therapy* / Q000235:genetics; D023303:Oxazolidinones / Q000627:therapeutic use; D010375:Pedigree; D017366:Serotonin Receptor Agonists / Q000494:pharmacology / Q000627:therapeutic use*; D018170:Sumatriptan / Q000627:therapeutic use*; D014230:Triazoles / Q000627:therapeutic use*; D014363:Tryptamines
D023303:Oxazolidinones; D017366:Serotonin Receptor Agonists; D014230:Triazoles; D014363:Tryptamines; C089750:zolmitriptan; C093622:rizatriptan; D018170:Sumatriptan