title: "On" response dysfunction in multifocal posterior pigment epitheliopathy.
abstract: OBJECTIVE
  To determine the electroretinographic properties of one patient with multifocal posterior pigment epitheliopathy.
  
  
  METHODS
  Rod and cone electroretinograms (ERGs) and photopic ERGs elicited by long-duration stimuli were studied in a patient with multifocal posterior pigment epitheliopathy.
  
  
  RESULTS
  The amplitudes of both the rod and cone ERGs were significantly reduced. Photopic ERGs elicited by long-duration stimuli demonstrated that the b-wave ("on" response) was abolished but the d-wave ("off" response) was reduced by only amplitude.
  
  
  CONCLUSIONS
  The ERG findings in multifocal posterior pigment epitheliopathy indicate that there is dysfunction not only of the photoreceptors but also in the signal transmission specific for the "on" pathway.
authors.affiliation: Department of Ophthalmology, Oita Medical University, Hasama-machi, Oita-ken, Japan.
authors.forename: Masamoto
authors.initials: M
authors.lastname: Imaizumi
authors.forename: Celso Soiti
authors.initials: CS
authors.lastname: Matsumoto
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Kimoto
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Furushima
authors.forename: Kazuo
authors.initials: K
authors.lastname: Nakatsuka
mesh_terms: D004596:Electroretinography; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000503:physiopathology*; D010857:Pigment Epithelium of Eye / Q000503:physiopathology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000503:physiopathology*; D014785:Vision, Ocular; D014795:Visual Pathways / Q000503:physiopathology*