[Clinical, biochemical, and morphological characteristics of chronic hepatitis with various etiology].
OBJECTIVE
To investigate clinicomorphological features in patients with chronic diffuse lesions of the liver with consideration of the etiological factor.


METHODS
Clinical, laboratory, serological and pathohistological examinations were performed in 67 patients with chronic hepatitis (CH).


RESULTS
Out of 48 patients with chronic viral hepatitis (CVH), 32(66.6%) demonstrated association of hepatic lesion with alcohol or drug abuse. Knodell activity in the liver was prevalent in drug abusers with CVH. Fat dystrophy and high de Ritis index were typical for alcoholics.


CONCLUSIONS
Viral hepatic lesions associated neither with alcohol nor drug abuse occur only in 1/3 of patients with CH.
Masevich
Ts G
TsG
Ermolaeva
L G
LG
D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000437:Alcoholism / Q000150:complications; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D005234:Fatty Liver / Q000209:etiology; D005260:Female; D006521:Hepatitis, Chronic / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology*; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D019966:Substance-Related Disorders / Q000150:complications
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin