title: Retrospective study of management of uterine sarcomas at Oxford 1990-1998: role of adjuvant treatment.
abstract: We report a retrospective study of 47 consecutive patients with uterine sarcoma treated at the Churchill Hospital in Oxford between 1990-1998. The mainstay of treatment was surgery with adjuvant chemotherapy and radiotherapy reserved for selected patients with early stage disease. Overall 1 and 2 year survival was 49% and 30% respectively compared with 73% and 55% in the group who received adjuvant chemotherapy/radiotherapy. Median survival was 11 months for the group as a whole compared to 32.9 months in the adjuvant therapy group. This is a retrospective review with small numbers and considerable selection bias, however, given the poor survival of patients with this disease, adjuvant treatment should be considered in future trials of patients with uterine sarcoma.
authors.affiliation: Department of Clinical Oncology, Churchill Hospital, Oxford, UK.
authors.forename: P J
authors.initials: PJ
authors.lastname: Riddle
authors.forename: C B
authors.initials: CB
authors.lastname: Echeta
authors.forename: S
authors.initials: S
authors.lastname: Manek
authors.forename: B A
authors.initials: BA
authors.lastname: Lavery
authors.forename: F M L
authors.initials: FM
authors.lastname: Charnock
authors.forename: I
authors.initials: I
authors.lastname: Mackenzie
authors.forename: T S
authors.initials: TS
authors.lastname: Ganesan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D012509:Sarcoma / Q000628:therapy*; D006113:United Kingdom; D014594:Uterine Neoplasms / Q000628:therapy*