Chemotherapy-induced nausea and vomiting.
Nausea and vomiting (N&V) is among the most distressing side effects of chemotherapy, despite the development of more efficacious antiemetic agents. As many as 60% of patients who receive cancer chemotherapy experience some degree of N&V. However, the actual incidence is difficult to determine with accuracy because of the variety of drugs, doses, and health conditions of the patients who receive cancer treatments. This article examines the state of the science related to chemotherapy-induced nausea and vomiting and reviews both pharmacologic and behavioral strategies that have demonstrated efficacy in managing these distressing symptoms.
Bender
Catherine M
CM
University of Pittsburgh School of Nursing, 3500 Victoria Street, Room 415, Victoria Building, Pittsburgh, PA 15261, USA. cbe100@pitt.edu
McDaniel
Roxanne W
RW
Murphy-Ende
Kathleen
K
Pickett
Mary
M
Rittenberg
Cynthia N
CN
Rogers
Miriam P
MP
Schneider
Susan M
SM
Schwartz
Rowena N
RN
D000932:Antiemetics / Q000008:administration & dosage / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000529:Complementary Therapies / Q000379:methods; D006801:Humans; D009325:Nausea / Q000139:chemically induced* / Q000517:prevention & control* / Q000523:psychology; D012702:Serotonin Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D014839:Vomiting / Q000139:chemically induced* / Q000517:prevention & control* / Q000523:psychology
D000932:Antiemetics; D000970:Antineoplastic Agents; D012702:Serotonin Antagonists