Axon guidance: growth cones make an unexpected turn.
Axonal growth cones can turn in response to minute concentration differences in extracellular guidance cues. Surprising new work suggests that these cues might steer the growth cone by inducing rapid local changes in protein levels.
Dickson
Barry J
BJ
Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030 Vienna, Austria. dickson@nt.imp.univie.ac.at
Senti
Kirsten-André
KA
D000818:Animals; D001369:Axons / Q000502:physiology*; D020439:Growth Cones / Q000502:physiology*; D009414:Nerve Growth Factors / Q000378:metabolism*; D000075388:Netrin-1; D012270:Ribosomes / Q000378:metabolism; D025521:Tumor Suppressor Proteins
D009414:Nerve Growth Factors; D025521:Tumor Suppressor Proteins; D000075388:Netrin-1