title: In vitro antifungal susceptibilities of Trichosporon species.
abstract: The in vitro activities of amphotericin B, itraconazole, fluconazole, voriconazole, posaconazole, and ravuconazole against 39 isolates of Trichosporon spp. were determined by the NCCLS M27-A microdilution method. The azoles tested appeared to be more potent than amphotericin B. Low minimal fungicidal concentration/MIC ratios were observed for voriconazole, posaconazole, and ravuconazole, suggesting fungicidal activity.
authors.affiliation: Laboratory for Mycology Research, Center for the Study of Emerging and Re-Emerging Pathogens, Division of Infectious Diseases, University of Texas-Houston Medical School, Houston, Texas 77030, USA. Elpida-Niki.I.Paphitou@uth.tmc.edu
authors.forename: Niki I
authors.initials: NI
authors.lastname: Paphitou
authors.forename: Luis
authors.initials: L
authors.lastname: Ostrosky-Zeichner
authors.forename: Victor L
authors.initials: VL
authors.lastname: Paetznick
authors.forename: Jose R
authors.initials: JR
authors.lastname: Rodriguez
authors.forename: Enuo
authors.initials: E
authors.lastname: Chen
authors.forename: John H
authors.initials: JH
authors.lastname: Rex
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D001393:Azoles / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D014250:Trichosporon / Q000187:drug effects*
chemical_list: D000935:Antifungal Agents; D001393:Azoles; D000666:Amphotericin B