[Secretory activity of adrenal glands in the offspring of white rats in conditions of low-intensity radiation effects].
It has been shown that in offsprings of both sex F1, one or both parents (F0) of which were exposed to X-ray radiation at a dose of 1 Gy (the dose rate was 0.4 Gy/min), and in offsprings of 6 generations (F1-F6), parents (F0) of which were placed in to the Chernobyl zone at a pubertal age, the hypertrophy and hyperactivity of isolated adrenals were observed in the different periods of life. The decrease of adrenals' reactivity in response to ACTH (0.1 ED/ml) was found in males of all generations. Most expressed damages of adrenal glands' reactivity were marked in males F6.
Mizina
T Iu
TIu
Research Institute of Biology and Biophysics, Tomsk State University, Tomsk, 634050 Russia. sit@res.tsu.ru
D000311:Adrenal Glands / Q000187:drug effects / Q000473:pathology / Q000502:physiology / Q000528:radiation effects*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000367:Age Factors; D000818:Animals; D003627:Data Interpretation, Statistical; D005260:Female; D006984:Hypertrophy; D008297:Male; D018811:Maternal Exposure; D018812:Paternal Exposure; D011210:Power Plants; D011829:Radiation Dosage; D018788:Radioactive Hazard Release; D051381:Rats; D012737:Sex Factors; D014455:Ukraine
D000324:Adrenocorticotropic Hormone