title: Eyelid lymphatics I: histochemical comparisons between the monkey and human.
abstract: OBJECTIVE
  To study the lymphatic drainage of the cynomolgus monkey and human eyelid and periocular tissue by means of histochemistry.
  
  
  METHODS
  Eyelid and periocular tissue from three cynomolgus monkeys undergoing sacrifice for glaucoma and retina research purposes and discarded tissue from a wedge resection of one human eyelid were used for histochemical analysis. Lymphatic capillaries were distinguished histochemically in monkey and human eyelids by light microscopy with a 5'-nucleotidase (5'-Nase) staining method. Identification of lymphatic vessels was based on strict morphologic criteria combined with specific 5'-Nase staining.
  
  
  RESULTS
  Histochemical analysis with 5'-nucleotidase revealed a subcutaneous and pretarsal lymphatic plexus in both the human and monkey.
  
  
  CONCLUSIONS
  Histochemical results demonstrate similar lymphatic plexi in the monkey and human. Future studies will help to clarify the lymphatic drainage pathways of monkey and human eyelids.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, USA. briggscook@yahoo.com
authors.forename: Briggs E
authors.initials: BE
authors.lastname: Cook
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Lucarelli
authors.forename: Bradley N
authors.initials: BN
authors.lastname: Lemke
authors.forename: Richard K
authors.initials: RK
authors.lastname: Dortzbach
authors.forename: Paul L
authors.initials: PL
authors.lastname: Kaufman
authors.forename: Lisa
authors.initials: L
authors.lastname: Forrest
authors.forename: Eric
authors.initials: E
authors.lastname: Greene
authors.forename: B'Ann T
authors.initials: BT
authors.lastname: Gabelt
mesh_terms: D015720:5'-Nucleotidase; D000818:Animals; D005143:Eyelids / Q000033:anatomy & histology*; D006801:Humans; D008208:Lymphatic System / Q000033:anatomy & histology* / Q000166:cytology; D008252:Macaca fascicularis; D013194:Staining and Labeling / Q000379:methods
chemical_list: D015720:5'-Nucleotidase