"On" response dysfunction in multifocal posterior pigment epitheliopathy.
OBJECTIVE
To determine the electroretinographic properties of one patient with multifocal posterior pigment epitheliopathy.


METHODS
Rod and cone electroretinograms (ERGs) and photopic ERGs elicited by long-duration stimuli were studied in a patient with multifocal posterior pigment epitheliopathy.


RESULTS
The amplitudes of both the rod and cone ERGs were significantly reduced. Photopic ERGs elicited by long-duration stimuli demonstrated that the b-wave ("on" response) was abolished but the d-wave ("off" response) was reduced by only amplitude.


CONCLUSIONS
The ERG findings in multifocal posterior pigment epitheliopathy indicate that there is dysfunction not only of the photoreceptors but also in the signal transmission specific for the "on" pathway.
Imaizumi
Masamoto
M
Department of Ophthalmology, Oita Medical University, Hasama-machi, Oita-ken, Japan.
Matsumoto
Celso Soiti
CS
Kimoto
Ken-Ichi
K
Furushima
Masatoshi
M
Nakatsuka
Kazuo
K
D004596:Electroretinography; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D010786:Photoreceptor Cells / Q000503:physiopathology*; D010857:Pigment Epithelium of Eye / Q000503:physiopathology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000503:physiopathology*; D014785:Vision, Ocular; D014795:Visual Pathways / Q000503:physiopathology*