Hyperplasia of pulmonary artery smooth muscle cells is causally related to overexpression of the serotonin transporter in primary pulmonary hypertension.
Eddahibi
Saadia
S
INSERM U492 et Departement de Physiologie, Créteil, France.
Humbert
Marc
M
Fadel
Elie
E
Raffestin
Bernadette
B
Darmon
Michèle
M
Capron
Frédérique
F
Simonneau
Gérald
G
Dartevelle
Philippe
P
Hamon
Michel
M
Adnot
Serge
S
D002352:Carrier Proteins / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D002455:Cell Division; D002478:Cells, Cultured; D015870:Gene Expression; D020022:Genetic Predisposition to Disease; D006801:Humans; D006965:Hyperplasia; D006976:Hypertension, Pulmonary / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D008168:Lung / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D026901:Membrane Transport Proteins; D009131:Muscle, Smooth, Vascular / Q000473:pathology*; D009419:Nerve Tissue Proteins; D011110:Polymorphism, Genetic; D011651:Pulmonary Artery / Q000378:metabolism / Q000473:pathology*; D012701:Serotonin / Q000502:physiology; D050486:Serotonin Plasma Membrane Transport Proteins
D002352:Carrier Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins; D012701:Serotonin