title: Long term behavior of lithographically prepared in vitro neuronal networks.
abstract: We measured the long term spontaneous electrical activity of neuronal networks with different sizes, grown on lithographically prepared substrates and recorded with multi-electrode-array technology. The time sequences of synchronized bursting events were used to characterize network dynamics. All networks exhibit scale-invariant Lévy distributions and long-range correlations. These observations suggest that different-size networks self-organize to adjust their activities over many time scales. As predictions of current models differ from our observations, this calls for revised models.
authors.affiliation: School of Physics and Astronomy, Raymond & Beverly Sackler Faculty of Exact Sciences, Tel-Aviv University, Tel-Aviv 69978, Israel.
authors.forename: Ronen
authors.initials: R
authors.lastname: Segev
authors.forename: Morris
authors.initials: M
authors.lastname: Benveniste
authors.forename: Eyal
authors.initials: E
authors.lastname: Hulata
authors.forename: Netta
authors.initials: N
authors.lastname: Cohen
authors.forename: Alexander
authors.initials: A
authors.lastname: Palevski
authors.forename: Eli
authors.initials: E
authors.lastname: Kapon
authors.forename: Yoash
authors.initials: Y
authors.lastname: Shapira
authors.forename: Eshel
authors.initials: E
authors.lastname: Ben-Jacob
mesh_terms: D004566:Electrodes; D008954:Models, Biological; D009415:Nerve Net / Q000502:physiology*; D009474:Neurons / Q000502:physiology