Microarray analysis indicates that pulmonary edema fluid from patients with acute lung injury mediates inflammation, mitogen gene expression, and fibroblast proliferation through bioactive interleukin-1.
Olman
Mitchell A
MA
Department of Medicine, Division of Pulmonary and Critical Care Medicine, the University of Alabama, Birmingham, AL 35294, USA. Olman@uab.edu
White
Kimberly E
KE
Ware
Lorraine B
LB
Cross
Michael T
MT
Zhu
Sha
S
Matthay
Michael A
MA
D001826:Body Fluids / Q000502:physiology*; D002448:Cell Adhesion; D002455:Cell Division; D005347:Fibroblasts / Q000378:metabolism / Q000502:physiology*; D015870:Gene Expression; D006801:Humans; D007249:Inflammation; D007375:Interleukin-1 / Q000502:physiology*; D008168:Lung / Q000473:pathology; D008934:Mitogens / Q000235:genetics* / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis; D011650:Pulmonary Alveoli / Q000378:metabolism; D011654:Pulmonary Edema / Q000209:etiology / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D012128:Respiratory Distress Syndrome / Q000150:complications*
D007375:Interleukin-1; D008934:Mitogens