title: [Proton MRS in a case of intracerebellar epidermoid].
abstract: We report a case of epidermoid, in which proton MR spectroscopy(MRS) provided additional information to MRI. The tumor revealed high signal intensity on T2-weighted images(WI) and low signal intensity on T1 WI. No enhancement was observed. Proton MRS was acquired with the Proton Regional Imaging of Metabolites(PRIME) method(TR/TE/measurements = 2,000 ms/136,272 ms/128 times). Proton MRS revealed lactate(Lac) peak at 1.33 ppm as negative peak at TE 136 ms and positive peak at TE 272 ms. N-acetylaspartate(NAA), creatine/phosphocreatine(Cr) and choline-containing compounds(Cho) were not visible. Lac peak without other peaks such as NAA, Cr, Cho is a unique finding of proton MRS for epidermoid and this could be useful in the differential diagnosis.
authors.affiliation: Department of Neurosurgery, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
authors.forename: Tomonori
authors.initials: T
authors.lastname: Isobe
authors.forename: Akira
authors.initials: A
authors.lastname: Matsumura
authors.forename: Izumi
authors.initials: I
authors.lastname: Anno
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshizawa
authors.forename: Yuji
authors.initials: Y
authors.lastname: Itai
authors.forename: Tadao
authors.initials: T
authors.lastname: Nose
mesh_terms: D000368:Aged; D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D004814:Epidermal Cyst / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D011522:Protons
chemical_list: D011522:Protons