HIV vaccine development in the nonhuman primate model of AIDS.
Development of a prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine is a leading priority in biomedical research. Much of this work has been done with the nonhuman primate model of AIDS. In a historical context, vaccine studies, which use this model, are summarized and discussed.
Smith
Stephen M
SM
Saint Michael's Medical Center and The New Jersey Medical School - UMDNJ, Newark, NJ, USA. ssmith1824@aol.com
D016915:AIDS Vaccines; D000163:Acquired Immunodeficiency Syndrome / Q000628:therapy*; D000818:Animals; D004195:Disease Models, Animal; D005822:Genetic Vectors / Q000627:therapeutic use; D006801:Humans; D007111:Immunity, Cellular; D011323:Primates; D018449:SAIDS Vaccines; D016097:Simian Acquired Immunodeficiency Syndrome / Q000628:therapy; D014764:Viral Proteins / Q000276:immunology
D016915:AIDS Vaccines; D018449:SAIDS Vaccines; D014764:Viral Proteins