Methods for the synthesis of unnatural amino acids.
A wide variety of methods have been used to prepare unnatural amino acids. This review covers methods reported between 2000 and the early part of 2001. Some of the approaches discussed are applications of established methods, but emphasis has been given to new approaches that could be generally applicable to large-scale syntheses, including catalytic reactions such as the Strecker reaction and biological approaches.
Ager
D J
DJ
RCCorp, PO BOX 59049, Schaumburg, IL 60195-0049, USA.
Fotheringham
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IG
D000596:Amino Acids / Q000096:biosynthesis / Q000138:chemical synthesis*; D002384:Catalysis; D003500:Cyclization; D004798:Enzymes / Q000737:chemistry; D007202:Indicators and Reagents; D013237:Stereoisomerism; D000637:Transaminases / Q000737:chemistry
D000596:Amino Acids; D004798:Enzymes; D007202:Indicators and Reagents; D000637:Transaminases