title: Use of AlloDerm for coverage of radial forearm free flap donor site.
abstract: OBJECTIVE
  To evaluate and discuss the role of acellular human dermal matrix (AlloDerm, LifeCell Corp., Branchburg, NJ) graft for coverage of radial forearm free flap donor site.
  
  
  METHODS
  Prospective, nonrandomized study.
  
  
  METHODS
  Fifty-two consecutive patients underwent harvest of 52 radial forearm fasciocutaneous free flaps. All 52 donor sites were covered by AlloDerm graft. Split-thickness skin graft was not used to reinforce the acellular dermal graft in the series. Clinical phases of healing, duration of healing, and donor site complications were studied.
  
  
  RESULTS
  No donor site complications except seroma formation in five patients was noted. This was treated by conservative measures. Full range of hand motion was allowed in 3 days. Complete healing occurred within 8 to 12 weeks. Scar contracture after complete healing was minimum in all patients. Range of motion of the hand and fingers during flexion, extension, supination, and pronation was identical on the operated and nonoperated sides.
  
  
  CONCLUSIONS
  AlloDerm graft is a viable alternative to split-thickness skin graft for coverage of the radial forearm free flap donor site.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, University of Southern California School of Medicine, Los Angeles, California 90033, USA. Sinha@hsc.usc.edu
authors.forename: Uttam K
authors.initials: UK
authors.lastname: Sinha
authors.forename: Charles
authors.initials: C
authors.lastname: Shih
authors.forename: Kristi
authors.initials: K
authors.lastname: Chang
authors.forename: Dale H
authors.initials: DH
authors.lastname: Rice
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D005542:Forearm / Q000601:surgery*; D006085:Graft Survival; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods; D012680:Sensitivity and Specificity; D016038:Skin Transplantation / Q000379:methods*; D013524:Surgical Flaps; D014945:Wound Healing / Q000502:physiology
chemical_list: C440568:Alloderm; D001672:Biocompatible Materials; D003094:Collagen