title: Protein degradation in Alzheimer's disease and aging of the brain.
authors.affiliation: Department of Neurology, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyoku, Kyoto 606-8507, Japan.
authors.forename: Teruyuki
authors.initials: T
authors.lastname: Tsuji
authors.forename: Shun
authors.initials: S
authors.lastname: Shimohama
mesh_terms: D000375:Aging / Q000378:metabolism*; D000544:Alzheimer Disease / Q000235:genetics / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000235:genetics / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D002154:Calpain / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism; D006801:Humans; D020961:Lewy Body Disease / Q000235:genetics / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism*; D010300:Parkinson Disease / Q000235:genetics / Q000378:metabolism; D010766:Phosphorylation; D053764:Presenilin-1; D053766:Presenilin-2; D011499:Protein Processing, Post-Translational; D051843:Synucleins; D025801:Ubiquitin / Q000378:metabolism; D016875:tau Proteins / Q000378:metabolism
chemical_list: D016229:Amyloid beta-Peptides; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; C508853:PSEN1 protein, human; C508861:PSEN2 protein, human; D053764:Presenilin-1; D053766:Presenilin-2; D051843:Synucleins; D025801:Ubiquitin; D016875:tau Proteins; D010450:Endopeptidases; D002154:Calpain