title: Fast MR imaging and ultrafast MR imaging of fetal central nervous system abnormalities.
abstract: The aims of this study were two: (1) to compare the efficacy of fast MRI (breath-hold fast spin-echo T2-weighted and fast gradient-echo T1-weighted sequence) and ultrafast MRI (half-Fourier acquisition single-shot turbo spin-echo sequence) in evaluation of fetal central nervous system (CNS) abnormalities at late gestational age, and (2) to compare the capability of fast MRI and ultrafast MRI to assess fetal CNS abnormalities with that of prenatal ultrasonography (US). Forty-nine women with fetuses at gestational ages of 26-39 weeks underwent fast MRI (29 patients) or ultrafast MRI (20 patients). In detection of motion artifact, visualization of the lateral and 4th ventricles, and differentiation between gray and white matter in cerebral hemispheres, ultrafast MRI was significantly superior to fast MRI (p< 0.0001, Mann-Whitney U test). In 25 of 43 cases, US and MR diagnoses were the same and consistent with postnatal diagnosis. In 10 of 43 cases, MRI demonstrated findings additional to or different from those of US, and MR findings were confirmed postnatally. MRI, particularly ultrafast MRI, is useful for demonstrating CNS abnormalities in situations in which US is suggestive but not definitive.
authors.affiliation: Department of Radiology, Osaka City General Hospital, Osaka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Shakudo
authors.forename: Y
authors.initials: Y
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Mochizuki
authors.forename: T
authors.initials: T
authors.lastname: Manabe
authors.forename: K
authors.initials: K
authors.lastname: Mura
authors.forename: R
authors.initials: R
authors.lastname: Matsu
authors.forename: J
authors.initials: J
authors.lastname: Oda
authors.forename: R
authors.initials: R
authors.lastname: Yamada
mesh_terms: D000757:Anencephaly / Q000175:diagnosis; D002490:Central Nervous System / Q000002:abnormalities*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005865:Gestational Age; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011247:Pregnancy; D011296:Prenatal Diagnosis