Extensive cerebral venous thrombosis associated with moderate hyperhomocyst(e)inemia and successfully treated with thrombolysis.
Cerebral venous thrombosis (CVT) is a relatively rare condition caused by multiple etiologies, usually secondary to hypercoagulable states. The optimal treatment is controversial, especially in the presence of hemorrhagic infarcts. We describe an unusual patient with extensive CVT associated with moderate hyperhomocyst(e)inemia who was aggressively treated with chemical and mechanical thrombolysis with an excellent outcome.
Chaves
Claudia
C
Department of Neurology, Lahey Clinic, Burlington, Mass, USA. claudia.j.chaves@lahey.org
Voetsch
Barbara
B
Loscalzo
Joseph
J
Caplan
Louis
L
Chavali
Ram
R
D000328:Adult; D002550:Cerebral Veins / Q000473:pathology*; D018450:Disease Progression; D006801:Humans; D020138:Hyperhomocysteinemia / Q000150:complications* / Q000188:drug therapy*; D020767:Intracranial Thrombosis / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D012720:Severity of Illness Index; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D016896:Treatment Outcome
D010959:Tissue Plasminogen Activator