title: Clinical study on 53 cases of cadaveric kidney transplantation at Osaka City University Hospital.
abstract: BACKGROUND
  In this study, we examined the effects of nonimmunological factors on cadaver kidney transplant.
  
  
  METHODS
  Fifty-three cadaver kidney transplant recipients were studied. They were divided into two groups, Group I ( donor age<60, n=38 ) and Group II ( donor age > or = 60, n=15). These patients were studied to determine whether donor age and recipient Body Mass Index (BMI) affected transplant outcome.
  
  
  RESULTS
  The 3 and 5-year overall graft / patient survival was 80.6 / 100% and 72.7 97.3%, respectively. The best S-Cr after transplantation was significantly (p<0.05) lower in Group I compared to Group II. The 1, 5 and 8-year graft survival was significantly (p<0.05) better in Group I. In the low BMI patients of Group II, 5-year graft survival was significantly (p<0.01) better than high BMI patients.
  
  
  CONCLUSIONS
  An aged cadaver donor was a risk factor for decreased posttransplant renal functions and lower graft survival. However, if a recipient with a low BMI can be selected, the outcome of cadaver kidney transplants from aged donors may be improved.
authors.affiliation: Department of Urology, Osaka City University, Graduate School of Medicine, Osaka, Japan. nakatani@msic.med.osaka-cu.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Nakatani
authors.forename: T
authors.initials: T
authors.lastname: Kim
authors.forename: J
authors.initials: J
authors.lastname: Uchida
authors.forename: N
authors.initials: N
authors.lastname: Kumada
authors.forename: K
authors.initials: K
authors.lastname: Tsuchida
authors.forename: Y
authors.initials: Y
authors.lastname: Takemoto
authors.forename: K
authors.initials: K
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Kishimoto
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002102:Cadaver; D006084:Graft Rejection; D006085:Graft Survival; D006785:Hospitals, University; D006801:Humans; D016030:Kidney Transplantation / Q000401:mortality