title: Syntheses of (+/-)-homoepibatidine analogues.
abstract: Syntheses of (+/-)-homoepibatidine analogues (2), which contain the 8-azabicyclo [3.2.1]octane ring system, were achieved by using palladium-catalyzed reductive-coupling reaction from 3 and the analgesic activity was tested by Mouse writhing antinociceptive assay.
authors.affiliation: College of Pharmacy, SungKyunKwan University, Suwon, Korea.
authors.forename: Yong-Hyun
authors.initials: YH
authors.lastname: Kim
authors.forename: Chang-Young
authors.initials: CY
authors.lastname: Oh
authors.forename: Kee-Young
authors.initials: KY
authors.lastname: Lee
authors.forename: Yiu-Suk
authors.initials: YS
authors.lastname: Lee
authors.forename: Young-Hoon
authors.initials: YH
authors.lastname: Jung
authors.forename: Hyun-Ju
authors.initials: HJ
authors.lastname: Park
authors.forename: Won-Hun
authors.initials: WH
authors.lastname: Ham
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000494:pharmacology; D002384:Catalysis; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018722:Nicotinic Agonists / Q000138:chemical synthesis* / Q000494:pharmacology; D010165:Palladium; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D018712:Analgesics, Non-Narcotic; D019086:Bridged Bicyclo Compounds, Heterocyclic; D007202:Indicators and Reagents; D018722:Nicotinic Agonists; D011725:Pyridines; D010165:Palladium; C082748:epibatidine