Oral pemphigus vulgaris occurring during pregnancy.
There have been few reports describing the occurrence of pemphigus vulgaris (PV) during pregnancy. The patient described in this case report is interesting because the PV that developed during her pregnancy was confined to her mouth. It has been suggested that prompt treatment with systemic steroids prevents development of PV in cutaneous tissues. In this case, early control of the condition is believed to have eliminated the need for high dose steroids throughout the remainder of the pregnancy. In addition, this therapeutic approach could have contributed to the birth of a baby free of PV. Resolution of the presenting oral symptoms allowed the mother to resume a normal diet, allaying her anxiety about the possible effects of poor nutritional intake on foetal development. Aspects of clinical management considered in this report include the choice of immunosuppressive therapy and the multidisciplinary care involving both dental and obstetric specialists.
Muhammad
Joseph K
JK
Department of Oral Surgery, Medicine and Pathology, University of Wales of Medicine, Cardiff, UK.
Lewis
Michael A O
MA
Crean
St John
SJ
D000284:Administration, Oral; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D005260:Female; D005882:Gingival Diseases / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D009061:Mouth Mucosa / Q000473:pathology; D010348:Patient Care Team; D010392:Pemphigus / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D011239:Prednisolone