title: [Clinical characteristics of endocarditis running with viral hepatitis in intravenous drug abusers].
abstract: Viral hepatitis (VH) was diagnosed in 65% of patients with infectious endocarditis (IE) abusing intravenous narcotic drugs. VH caused recurrent course of IE in 8% examinees. The virusological tests of the blood for HBs-antigen or antibodies to viral hepatitis C were positive in 39 patients (group 1) and negative in 21 patients (group 2). VHB, VHC, VHB + VHC were diagnosed in 15, 57 and 28% patients, respectively. An acute course of IE was observed in 72% patients from group 1 and 76% patients from group 2, respectively, subacute course--in 20 and 24%, respectively, recurrent in 8% and 0%, respectively. IE patients with VH often had thrombohemorrhagic complications. DIC syndrome was detected in 25 and 4% patients, hemophthisis--in 33 and 28%, nephritis--in 71 and 48% patients, acute cerebral ischemia--in 7 and 4%, acute myocardial infarction--in 71 and 4%, hypocoagulation--in 53 and 8%, hypercoagulation--in 29 and 50% patients from group 1 and 2, respectively.
authors.forename: A A
authors.initials: AA
authors.lastname: Demin
authors.forename: V P
authors.initials: VP
authors.lastname: Drobyshev
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Vel'ter
mesh_terms: D000293:Adolescent; D000328:Adult; D004696:Endocarditis / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D015819:Substance Abuse, Intravenous / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology