title: A unified theory of gene expression.
abstract: The human genome has been called "the blueprint for life." This master plan is realized through the process of gene expression. Recent progress has revealed that many of the steps in the pathway from gene sequence to active protein are connected, suggesting a unified theory of gene expression.
authors.affiliation: Syngenta Central Toxicology Laboratory, Alderley Park, Cheshire SK10 4TJ, United Kingdom.
authors.forename: George
authors.initials: G
authors.lastname: Orphanides
authors.forename: Danny
authors.initials: D
authors.lastname: Reinberg
mesh_terms: D021581:Active Transport, Cell Nucleus / Q000502:physiology; D002843:Chromatin / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D005786:Gene Expression Regulation; D015894:Genome, Human; D006657:Histones / Q000378:metabolism; D006801:Humans; D008957:Models, Genetic; D009687:Nuclear Proteins / Q000378:metabolism; D011401:Promoter Regions, Genetic; D012319:RNA Polymerase II / Q000378:metabolism*; D012323:RNA Processing, Post-Transcriptional
chemical_list: D002843:Chromatin; D004268:DNA-Binding Proteins; D006657:Histones; D009687:Nuclear Proteins; D012319:RNA Polymerase II