Highly accelerating effect of lewis acids on ruthenium(II)-catalyzed radical addition reactions.
The intramolecular ruthenium(II)-catalyzed radical addition of the trichloroacetyl pendant group to the 2-oxazolone skeleton is greatly enhanced in the presence of catalytic Lewis acids including rare earth metal triflates, thus providing a convenient route to a highly potential chiral synthon for vic-amino alcohols.
Hoshimoto
Shigeki
S
Faculty of Pharmaceutical Sciences, Kumamoto University, Japan.
Matsunaga
Hirofumi
H
Wada
Masako
M
Kunieda
Takehisa
T
D000143:Acids / Q000737:chemistry*; D002384:Catalysis; D009682:Magnetic Resonance Spectroscopy; D012428:Ruthenium / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment
D000143:Acids; D012428:Ruthenium