Old and new antibiotics for pediatric pneumonia.
A variety of antibiotics, both parenteral and oral, are available to the clinician caring for a child with pneumonia. Although viral pathogens are the common etiologic agents causing community-acquired pneumonia, significant morbidity and mortality exists from disease caused by bacteria and atypical pneumonia agents. Treatment of nosocomial bacterial pneumonia has become particularly difficult with ever-increasing resistance documented in hospital-acquired organisms. This article discusses antibiotic therapy based on clinical presentation and based on identified pathogens, with a discussion of mechanisms of antibiotic resistance and the newer agents that have been designed to meet this continually evolving challenge.
Bradley
John S
JS
University of California San Diego, School of Medicine, San Diego, CA, USA.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006801:Humans; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000382:microbiology* / Q000517:prevention & control
D000900:Anti-Bacterial Agents