The impact of microwave-assisted organic chemistry on drug discovery.
Microwave-assisted organic synthesis (MAOS) is rapidly becoming recognized as a valuable tool for easing some of the bottlenecks in the drug discovery process. This article outlines the basic principles behind the technology and summarizes the areas in which microwave technology has made an impact, to date.
Wathey
Bernard
B
BioFocus, 130, Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent, UK ME9 8AZ. bwathey@biofocus.com
Tierney
Jason
J
Lidström
Pelle
P
Westman
Jacob
J
D002625:Chemistry, Organic / Q000295:instrumentation*; D008872:Microwaves; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification; D010600:Pharmacology / Q000295:instrumentation*; D013242:Sterilization
D004364:Pharmaceutical Preparations