Biotransformation reactions of five-membered aromatic heterocyclic rings.
Dalvie
Deepak K
DK
Pharmacokinetics, Dynamics and Drug Metabolism, Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, USA. Deepak_k_Dalvie@groton.pfizer.com
Kalgutkar
Amit S
AS
Khojasteh-Bakht
S Cyrus
SC
Obach
R Scott
RS
O'Donnell
John P
JP
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005663:Furans / Q000378:metabolism; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D007093:Imidazoles / Q000378:metabolism; D007211:Indoles / Q000378:metabolism; D007555:Isoxazoles / Q000378:metabolism; D008956:Models, Chemical; D015394:Molecular Structure; D010069:Oxadiazoles / Q000378:metabolism; D010080:Oxazoles / Q000378:metabolism; D011720:Pyrazoles / Q000378:metabolism; D011758:Pyrroles / Q000378:metabolism; D013777:Tetrazoles / Q000378:metabolism; D013830:Thiadiazoles / Q000378:metabolism; D013844:Thiazoles / Q000378:metabolism; D013876:Thiophenes / Q000378:metabolism; D014230:Triazoles / Q000378:metabolism; D015262:Xenobiotics / Q000378:metabolism*
D005663:Furans; D006576:Heterocyclic Compounds, 4 or More Rings; D007093:Imidazoles; D007211:Indoles; D007555:Isoxazoles; D010069:Oxadiazoles; D010080:Oxazoles; D011720:Pyrazoles; D011758:Pyrroles; D013777:Tetrazoles; D013830:Thiadiazoles; D013844:Thiazoles; D013876:Thiophenes; D014230:Triazoles; D015262:Xenobiotics; D003577:Cytochrome P-450 Enzyme System