Solution-phase synthesis of aminooxy peptoids in the C to N and N to C directions.
[structure: see text] Aminooxy peptoids, which are potential peptidomimetics, were synthesized by a stepwise monomer assembly. Ns-protected N-substituted aminooxyacetate tert-butyl esters were used as a monomer in both the C to N and the N to C directions. Submonomer synthesis of aminooxy peptoids is also described.
Shin
Injae
I
Department of Chemistry, Yonsei University, Seoul 120-749, Korea. injae@yonsei.ac.kr
Park
Kisoo
K
D000588:Amines / Q000737:chemistry*; D018716:Molecular Mimicry; D010455:Peptides / Q000138:chemical synthesis*; D034444:Peptoids
D000588:Amines; D010455:Peptides; D034444:Peptoids