title: [Intestinal lymphoma associated with Behçet disease].
abstract: The association of Behçet's disease and non-Hodgkin's lymphoma is very rare. The first case of primary intestinal lymphoma with intestinal Behçet's disease is reported. A 37 year-old woman had been treated for Behçet's disease with colchicine for 2 years. In July 1997, she developed uveitis and was treated by monthly intravenous pulses of cyclophosphamide for 6 months, but uveitis persisted; so cyclophosphamide was replaced by cyclosporin 300 mg/day. One month later, she suffered from diarrhea. Colonoscopy showed ileocoecal ulcerations. Histological examination of surgical biopsy revealed B large cell type lympocytic malignant lymphoma and vasculitis lesions compatible with intestinal Behçet's disease. Cyclosporin was stopped and treatment with prednisone was instituted. The relationship between non-Hodgkin's lymphoma and immunosuppressive drugs in Behçet's disease is discussed.
authors.affiliation: Service de Médecine Interne, Hôpital La Rabta, 1007 Tunis, Tunisie. houman.habib@rns.tn
authors.forename: M H
authors.initials: MH
authors.lastname: Houman
authors.forename: I
authors.initials: I
authors.lastname: Ben Ghorbel
authors.forename: S
authors.initials: S
authors.lastname: B'Chir-Hamzaoui
authors.forename: M
authors.initials: M
authors.lastname: Lamloum
authors.forename: N
authors.initials: N
authors.lastname: Kchir
authors.forename: M
authors.initials: M
authors.lastname: Miled
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications*