Spiral breakup in an array of coupled cells: the role of the intercellular conductance.
We study numerically how the intercellular conductance affects the process of spiral breakup in an array of coupled excitable cells. The cell dynamics are described by the Aliev-Panfilov model, and the intercellular connection is made via Ohmic elements. We find that decreasing intercellular conductance can prevent the breaking up of a spiral wave into a complex spatiotemporal pattern. We study the mechanism of this effect and show that the breakup disappears because of increasing the diastolic interval of an initial spiral wave.
Panfilov
A V
AV
Department of Theoretical Biology, Utrecht University, Padualaan 8, Utrecht, 3584 CH, The Netherlands.
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D004553:Electric Conductivity; D006801:Humans; D008954:Models, Biological; D009206:Myocardium / Q000166:cytology*