title: Treatment of renovascular disease with percutaneous stent insertion: long-term outcomes.
abstract: Renal artery stenosis is a common, progressive cause of hypertension and renal impairment, and is frequently treated with percutaneous transluminal dilatation and stenting. The outcome of this procedure is still being evaluated. The records of 198 consecutive patients who had stents inserted at the Royal Melbourne Hospital were analysed retrospectively, and adequate follow-up information on 148 (75%), in whom a total of 182 renal arteries had been treated was obtained. Technical success was achieved in 144 patients (97%). Complications occurred in 19 patients (13.3%), with major complications occurring in 10 (7.0%) and one death occurring in relation to the procedure. A fall in average systolic blood pressure of 13.2 mmHg (12.1-14.3 mmHg) was seen and a fall in diastolic blood pressure of 10.1 mmHg (9.3-10.9 mmHg), without an increase in the number of antihypertensive drugs used. Renal function remained stable in the majority of patients, particularly those who had minimal baseline renal impairment. Restenosis was common after 6 months, occurring eventually in 29% of screened patients, but was not shown to affect clinical outcomes. Insertion of renal artery stents is a safe and effective treatment for renal artery stenosis.
authors.affiliation: Department of Nephrology, Royal Melbourne Hospital, Melbourne, Australia. vlado@perkovic.net
authors.forename: V
authors.initials: V
authors.lastname: Perkovic
authors.forename: K R
authors.initials: KR
authors.lastname: Thomson
authors.forename: P J
authors.initials: PJ
authors.lastname: Mitchell
authors.forename: R N
authors.initials: RN
authors.lastname: Gibson
authors.forename: N
authors.initials: N
authors.lastname: Atkinson
authors.forename: P L
authors.initials: PL
authors.lastname: Field
authors.forename: G J
authors.initials: GJ
authors.lastname: Becker
mesh_terms: D000800:Angioplasty, Balloon; D001794:Blood Pressure; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D006978:Hypertension, Renovascular / Q000628:therapy*; D008297:Male; D012008:Recurrence; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D015607:Stents; D015996:Survival Rate; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D003404:Creatinine