One week of exposure to 50 Hz, vertical magnetic field does not reduce urinary 6-sulphatoxymelatonin excretion of male wistar rats.
The effect of exposure to 100 or 50 microT, 50 Hz, vertical magnetic field on the excretion of 6-sulphatoxymelatonin (6SM) in the nocturnal urine of rats was studied. Twelve male Wistar rats were kept under 12:12 hr light:dark conditions. The nocturnal urine of animals was collected in metabolic cages over 4 consecutive weeks. The concentration of 6SM in the rat urine was measured by 125I radioimmunoassay and normalized to creatinine concentration. After the first week of urine collection, 6 rats were exposed to 100 microT or 50 microT flux density magnetic fields (MF) for 8 hr daily for 1 week. It was found that the excretion of the primary metabolite of melatonin in the urine, 6SM, did not show statistically significant changes during and after magnetic field exposure.
Bakos
József
J
Department of Non-ionizing Radiation, National "Frédéric Joliot-Curie" Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary.
Nagy
Noémi
N
Thuróczy
György
G
Szabó
László D
LD
D000818:Animals; D008280:Magnetics; D008297:Male; D008550:Melatonin / Q000031:analogs & derivatives* / Q000378:metabolism / Q000652:urine*; D023421:Models, Animal; D017440:Photoperiod; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
C054513:6-sulfatoxymelatonin; D008550:Melatonin