title: [Adenocarcinoma of the cervix--stage IB: results of treatment and prognostic factors].
abstract: The study presents the results of treatment of 63 women with stage IB adenocarcinoma of the cervix. The treatment consist of radical Wertheim-Meigs hysterectomy with adjuvant brachytherapy or external beam irradiation. A statistical analysis with Kaplan-Meier and cox model was conducted to assess the influence of selected prognostic factors on survival. After 5-year long follow-up 73.4% of patients were alive without recurrence. The results of univariate analysis showed that metastatic pelvic nodes, cervical tumor size of more than 4 cm and the presence of microscopic parametrial infiltration had a statistically significant negative influence on survival. In a multivariate analysis tumor size of more than 4 cm and microscopic parametrial involvement had an independent negative impact on survival (relative risk of death--12.1 and 15.7).
authors.affiliation: Kliniki Nowotworów Narzadów Płciowych Kobiecych Centrum Onkologii-Instytutu w Warszawie.
authors.forename: G
authors.initials: G
authors.lastname: Panek
authors.forename: M
authors.initials: M
authors.lastname: Bidziński
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000628:therapy*; D000328:Adult; D000368:Aged; D001918:Brachytherapy / Q000379:methods; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011379:Prognosis; D016499:Radioimmunotherapy / Q000379:methods; D018714:Radiotherapy, Adjuvant; D012307:Risk Factors; D015996:Survival Rate; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000628:therapy*