title: Safety and efficacy of one stage off-pump coronary artery operation and carotid endarterectomy.
abstract: BACKGROUND
  Patients with concomitant occlusive disease of coronary and carotid arteries remain at high risk of perioperative stroke and myocardial infarction. Combined coronary artery bypass grafting on cardiopulmonary bypass and carotid endarterectomy has been shown to give good results for this category of patients. In the present study, we analyzed our results of off-pump coronary artery bypass grafting and carotid endarterectomy as a one-stage procedure.
  
  
  METHODS
  Between January 1997 and December 2000, 82 patients underwent combined off-pump coronary artery bypass grafting and carotid endarterectomy. All patients were evaluated by preoperative carotid duplex scanning and carotid angiography. All patients had more than or equal to 70% carotid artery stenosis. There were 35 asymptomatic patients (42.7%) and 47 symptomatic patients (57.3%). Carotid endarterectomy was performed before coronary artery bypass grafting in all the patients.
  
  
  RESULTS
  There were 66 males (80.5%) and 16 females (19.5%) with a mean age of 63+/-8 years. The average number of grafts was 3.4+/-0.8. There was no hospital mortality. One patient had perioperative myocardial infarction. None of the patients had stroke. One patient had transient neurologic deficit and 1 patient had temporary 12th nerve dysfunction; both recovered completely. There was no incidence of neck wound infection, although 1 patient developed neck hematoma that required reexploration. At a mean follow-up of 2.2+/-0.7 years, 1 patient required contralateral carotid endarterectomy and 1 patient died because of cardiac failure.
  
  
  CONCLUSIONS
  Combined off-pump coronary artery bypass grafting and carotid endarterectomy is a safe and effective procedure in patients with significant concomitant carotid and coronary artery disease.
authors.affiliation: Department of Cardiovascular Surgery, Escorts Heart Institute and Research Centre, New Delhi, India. meharwal@hotmail.com
authors.forename: Zile Singh
authors.initials: ZS
authors.lastname: Meharwal
authors.forename: Anil
authors.initials: A
authors.lastname: Mishra
authors.forename: Naresh
authors.initials: N
authors.lastname: Trehan
mesh_terms: D000368:Aged; D016893:Carotid Stenosis / Q000150:complications* / Q000601:surgery; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000379:methods; D003327:Coronary Disease / Q000150:complications* / Q000601:surgery; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies