title: Recurrent stroke as a manifestation of primary angiitis of the central nervous system in a patient infected with human immunodeficiency virus.
abstract: BACKGROUND
  Cerebral vasculitis in patients infected with human immunodeficiency virus (HIV) is usually related to additional or secondary infectious agents other than neoplastic diseases or HIV itself.
  
  
  OBJECTIVE
  To describe a 31-year-old patient infected with HIV who presented with 2 recurrent, acute episodes of neurologic impairment in a 5-month period.
  
  
  METHODS
  Comparison of clinical and histologic data between the present case and previously published cases.
  
  
  METHODS
  Community hospital.
  
  
  METHODS
  A 31-year-old, HIV-infected patient with recurrent strokes and chronic lymphocytic meningitis.
  
  
  METHODS
  After ruling out cardiac embolisms and coagulation disorders, the presence of central nervous system vasculitis, probably secondary to an infectious process, was suspected based on the clinical examination and cerebrospinal fluid abnormalities.
  
  
  RESULTS
  Necropsy findings suggest the diagnosis of primary angiitis of the central nervous system, and the only infectious agent that could be found was HIV.
  
  
  CONCLUSIONS
  Histologic studies were compatible with a diagnosis of primary angiitis of the central nervous system, but the pathogenic role of HIV in the genesis of the vasculitic process cannot be elucidated.
authors.affiliation: Department of Internal Medicine, Corporació Sanitària Parc Taulí, Parc Taulí s/n, Sabadell, 08208 Barcelona, Spain. msala@cspt.es
authors.forename: Carmen
authors.initials: C
authors.lastname: Nogueras
authors.forename: Montserrat
authors.initials: M
authors.lastname: Sala
authors.forename: Mercè
authors.initials: M
authors.lastname: Sasal
authors.forename: Jaume
authors.initials: J
authors.lastname: Viñas
authors.forename: Natalia
authors.initials: N
authors.lastname: Garcia
authors.forename: Maria-Rosa
authors.initials: MR
authors.lastname: Bella
authors.forename: Manuel
authors.initials: M
authors.lastname: Cervantes
authors.forename: Ferran
authors.initials: F
authors.lastname: Segura
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D015658:HIV Infections; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008587:Meningitis, Viral / Q000150:complications / Q000473:pathology; D012008:Recurrence; D020521:Stroke / Q000209:etiology*; D020293:Vasculitis, Central Nervous System / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000821:virology*