[The development of nanoparticles on DNA isolation and purification].
Magnetic nanoparticle is a new solid-support of affinity chromatography. The particle size is small and it has super-paramagnetism. It has large surface area and it can be endowed many reaction groups such as streptavidin, antibody or DNA fragments. The target DNA can be separated in magnetic field. The magnetic nanoparticle is applied in the biomolecular field gradually and it has a very broad prospect of appliance.
Sun
M L
ML
Department of Vascular Surgery, Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China. sml21@263.net
Zhang
H
H
D000906:Antibodies / Q000737:chemistry; D002846:Chromatography, Affinity / Q000379:methods*; D004247:DNA / Q000302:isolation & purification*; D004574:Electromagnetic Fields; D004578:Electron Spin Resonance Spectroscopy / Q000639:trends; D015335:Molecular Probes; D036103:Nanotechnology / Q000639:trends; D010316:Particle Size; D019809:Streptavidin / Q000737:chemistry; D013499:Surface Properties
D000906:Antibodies; D015335:Molecular Probes; D004247:DNA; D019809:Streptavidin