title: Inflammatory bowel disease in Greece-- a hospital-based clinical study of 172 consecutive patients.
abstract: BACKGROUND
  It has been suggested that inflammatory bowel disease (IBD) has a milder course in Greece than in other Western countries. The purpose of our study was to assess the clinical picture of IBD in a hospital-based sample of IBD patients, followed from January 1986 to May 2001.
  
  
  METHODS
  Retrospective study of 172 patients: 130 with UC followed up for 1-360 months (mean 66+/-57 months) and 42 with CD for 1-240 months (mean: 51.85+/-63.68 months).
  
  
  RESULTS
  63 UC patients (48%) required hospitalization, 30 (23%) on the first attack; 72 (55%) had left sided colitis and 23 (18%) pancolitis; in 6 cases, (5%), surgical intervention was indicated at onset, 4 (3%) were operated. During FU, 15 patients (11.5%) were operated, 4 (3%) as medical emergencies, 3 (2%) due to colon cancer, the others for intractable colitis or long-standing disease; 5 patients (4%) developed toxic dilation of the colon, 3 (2%) developed colon cancer and 4 (4%) extraintestinal malignancies. 7 patients (5%) died; 2 (1.5%) due to the disease and the remainder for other causes. 19 CD patients (45%) had ileocolitis and 14 (33%) colitis; 22 (52%) needed hospitalization on the first attack. In 12 patients (29%) surgical intervention was required on initial onset or during FU. One patient developed colon cancer (2%). Two men died (5%) from myocardial infarction.
  
  
  CONCLUSIONS
  IBD does not have a milder course in Greece than in other European populations.
authors.affiliation: Department of Pathophysiology,Gastroenterology Section, University of Athens Medical School, "Laiko" General Hospital, Athens, Greece. aarchim@hotmail.com
authors.forename: Athanasios J
authors.initials: AJ
authors.lastname: Archimandritis
authors.forename: Dimitris
authors.initials: D
authors.lastname: Kourtesas
authors.forename: Stavros
authors.initials: S
authors.lastname: Sougioultziz
authors.forename: Apostolos
authors.initials: A
authors.lastname: Giontzis
authors.forename: Pantelis
authors.initials: P
authors.lastname: Grigoriadis
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Davaris
authors.forename: Michalis
authors.initials: M
authors.lastname: Tzivras
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000453:epidemiology; D003424:Crohn Disease / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006115:Greece; D006761:Hospitals; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D013997:Time Factors