Epilepsy in the elderly.
The active prevalence rate of epilepsy among persons over 65 years of age is approximately 1.5%, about twice the rate in younger adults. Treatment of epilepsy in the elderly is complicated by alterations in drug metabolism, use of concomitant medications, and multiple medical problems. Drug interactions are a major issue, and a full knowledge of the isoenzyme profile and protein-binding characteristics of each drug (antiepileptic and other) must be known.
Leppik
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MINCEP Epilepsy Care, 5775 Wayzata Boulevard, Suite 200, Minneapolis, MN 55416, USA.
D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use*; D004827:Epilepsy / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans
D000927:Anticonvulsants