title: Combined aerobic and resistance exercise improves glycemic control and fitness in type 2 diabetes.
abstract: We investigated the effect of an 8 week circuit training (CT) program, combining aerobic and resistance exercise, on indices of glycemic control, cardiorespiratory fitness, muscular strength and body composition in 16 subjects (age 52 +/- 2 years) with type 2 diabetes using a prospective randomised crossover protocol. Submaximal exercise heart rate and rate pressure product were significantly lower after training (P<0.05), whilst ventilatory threshold increased (11.8 +/- 0.7 vs 13.8 +/- 0.6 ml kg(-1)min(-1), P<0.001). Muscular strength also increased with training (403 +/- 30 to 456 +/- 31 kg, P<0.001), whilst skinfolds (148.7 +/- 11.5 vs 141.1 +/- 10.7 mm, P<0.05), % body fat (29.5 +/- 1.0 vs 28.7 +/- 1.1%, P<0.05) and waist:hip ratio (99.2 +/- 1.5 vs 97.9 +/- 1.4%, P<0.05) significantly decreased. Concurrently, peak oxygen uptake (P<0.05) and exercise test duration (P<0.001) increased following training, whilst glycated hemoglobin (P<0.05) and fasting blood glucose (P<0.05) decreased. CT is an effective method of training that improved functional capacity, lean body mass, strength and glycemic control in subjects with type 2 diabetes.
authors.affiliation: Department of Human Movement and Exercise Science, The University of Western Australia, Nedlands, WA 6907, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Maiorana
authors.forename: Gerard
authors.initials: G
authors.lastname: O'Driscoll
authors.forename: Carmel
authors.initials: C
authors.lastname: Goodman
authors.forename: Roger
authors.initials: R
authors.lastname: Taylor
authors.forename: Daniel
authors.initials: D
authors.lastname: Green
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D001794:Blood Pressure; D001823:Body Composition; D015992:Body Mass Index; D018592:Cross-Over Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000503:physiopathology; D010809:Physical Fitness / Q000502:physiology*; D015656:Respiratory Mechanics
chemical_list: D001786:Blood Glucose; D008055:Lipids