[Ataxic form of Guillain-Barré syndrome associated with anti-GD1b IgG antibody].
A 28-year-old man was admitted after developing acute onset unstable gait following acute enteritis. Neurological examination revealed mild weakness in four limbs, areflexia and ataxia. Serum obtained from the patient during the acute stage contained a high titer of anti-GD1b IgG antibody. Because the patient showed obvious cerebellar ataxia unrelated to muscle weakness, without ophthalmoplegia or proprioceptive sensory disturbance, we concluded that he had ataxic form of Guillain-Barré syndrome (GBS) (Richter, 1962). Although ataxic GBS is not an established conception, one should pay attention to the possible existence of such a rare GBS variant. It is necessary to accumulate additional case reports to clarify the association between ataxic GBS and anti-ganglioside antibodies.
Ichikawa
H
H
Department of Neurology, Showa University School of Medicine.
Susuki
K
K
Yuki
N
N
Kawamura
M
M
D000328:Adult; D015415:Biomarkers / Q000097:blood; D002524:Cerebellar Ataxia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D005732:Gangliosides / Q000276:immunology*; D020275:Guillain-Barre Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D008297:Male; D016896:Treatment Outcome
D015415:Biomarkers; D005732:Gangliosides; D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous; C033851:ganglioside, GD1b