title: A validated high performance liquid chromatographic method for the analysis of Goldenseal.
abstract: Goldenseal (Hydrastis canadensis L.) has emerged as one of the top ten herbal supplements on the worldwide market. A rapid, simple and validated high performance liquid chromatographic method, with photodiode array detection, has been developed for the analysis of commercial Goldenseal products. Samples were treated by sonication with acidified methanol/water. The method was validated for LOD, LOQ, linearity, reproducibility and recovery with good results.
authors.affiliation: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 60612, USA.
authors.forename: Wenkui
authors.initials: W
authors.lastname: Li
authors.forename: John F
authors.initials: JF
authors.lastname: Fitzloff
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D044182:Benzylisoquinolines; D001599:Berberine / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D028321:Plant Preparations / Q000032:analysis*; D015203:Reproducibility of Results
chemical_list: D000470:Alkaloids; D044182:Benzylisoquinolines; D028321:Plant Preparations; D001599:Berberine; C013024:hydrastine