title: Malleus fixation: clinical and histopathologic findings.
abstract: The goals of this study were to review important clinical and histopathologic features of malleus fixation. Ten clinical cases and 10 histopathologic cases of malleus fixation were identified. For the clinical cases, preoperative clinical data, surgical findings, and preoperative and postoperative audiometric findings were reviewed. Ninety percent of the clinical cases achieved significant reduction of the air-bone gap after operation. Two thirds of these cases had an air-bone gap of 10 dB or less, and the remainder had air-bone gaps between 20 and 28 dB after operation. For the temporal bone cases, clinical data, histopathologic findings, and other otologic diagnoses were reviewed. Malleus fixation can be idiopathic or a result of trauma, chronic otitis media, or developmental anomalies. It is a cause of hearing loss that is likely to be more common than the number of diagnoses would indicate. Certain audiometric findings may lead one to suspect the diagnosis. The surgical approach used depends on the individual anatomy, and surgery is usually highly effective in improving hearing.
authors.affiliation: Department of Otology and Laryngology, Harvard Medical School and the Massachusetts Eye and Ear Infirmary, Boston, USA.
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Harris
authors.forename: Ritvik P
authors.initials: RP
authors.lastname: Mehta
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Nadol
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001299:Audiometry; D001844:Bone Conduction; D002648:Child; D002908:Chronic Disease; D005260:Female; D006314:Hearing Loss, Conductive / Q000175:diagnosis / Q000209:etiology*; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008307:Malleus / Q000293:injuries / Q000473:pathology*; D008875:Middle Aged; D010001:Osteitis Deformans; D010026:Osteosclerosis / Q000150:complications* / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D010033:Otitis Media / Q000150:complications; D010173:Palpation; D015995:Prevalence; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013201:Stapes Surgery; D016896:Treatment Outcome; D014433:Tympanoplasty