New erythrolides from the Caribbean gorgonian octocoral Erythropodium caribaeorum.
Seven new briarane diterpenes, erythrolides K-Q (1-7), as well as the known compounds erythrolides A, B, C, F, and J have been isolated from samples of the Caribbean gorgonian Erythropodium caribaeorumcollected at Buccoo Reef and Flying Reef, Tobago. The structures of the new compounds were determined by high-resolution 1H and 13C NMR spectroscopy utilizing COSY, HMBC, HMQC, and NOESY experiments. The structures of erythrolides K and P were confirmed and their relative stereochemistry determined by X-ray crystallographic analysis.
Banjoo
Darryl
D
Department of Chemistry, University of the West Indies, St. Augustine, Trinidad and Tobago.
Mootoo
Baldwin S
BS
Ramsewak
Russel S
RS
Sharma
Rawatee
R
Lough
Alan J
AJ
McLean
Stewart
S
Reynolds
William F
WF
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003063:Cnidaria / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism; D014300:Trinidad and Tobago
D004224:Diterpenes