Nowadays it is preceptive to perform chromosomal studies with high resolution G-bands and FISH techniques when necessary.
Martínez-Frías
M L
ML
Rodríguez
L
L
López
F
F
Bermejo
E
E
Rodríguez-Pinilla
E
E
D000015:Abnormalities, Multiple / Q000235:genetics / Q000473:pathology; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D003398:Craniosynostoses / Q000473:pathology; D020732:Cytogenetic Analysis / Q000379:methods*; D003937:Diagnosis, Differential; D006228:Hand Deformities, Congenital / Q000473:pathology; D016142:Holoprosencephaly / Q000473:pathology; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D013577:Syndrome