Is there an upper age limit for bone marrow transplantation?
Advances in hematopoietic cell transplantation have reduced the toxicity of both allogeneic and autologous transplantation. Decisions regarding the feasibility of transplantation should be individualized, and based upon physiological rather than chronological age.
Popplewell
L L
LL
Division of Hematology and Bone Marrow Transplantation, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
Forman
S J
SJ
D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D000368:Aged; D016026:Bone Marrow Transplantation / Q000009:adverse effects / Q000379:methods; D002908:Chronic Disease; D006086:Graft vs Host Disease / Q000209:etiology; D019337:Hematologic Neoplasms / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods; D006801:Humans; D008212:Lymphocyte Depletion; D008875:Middle Aged; D011379:Prognosis; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D016896:Treatment Outcome