A meta-analysis of effectiveness of influenza vaccine in persons aged 65 years and over living in the community.
OBJECTIVE
To estimate the effectiveness of inactivated influenza vaccine in persons aged 65 years and over living in the community.


METHODS
A meta-analysis of studies selected using predetermined criteria without language restriction.


CONCLUSIONS
Influenza vaccine was effective in reducing influenza-like illness by 35% (95% confidence interval (CI) 19-47%), hospitalization for pneumonia and influenza by 33% (CI 27-38%), mortality following hospitalization for pneumonia and influenza by 47% (CI 25-62%); and mortality from all causes by 50% (CI 45-56%).
Vu
Trang
T
Victorian Public Health Training Program, Charles Connibere Building, The Royal Melbourne Hospital, Flemington Road, Parkville, Vic. 3050, Australia. trang.vu@mh.org.au
Farish
Stephen
S
Jenkins
Mark
M
Kelly
Heath
H
D000368:Aged; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control; D005060:Europe / Q000453:epidemiology; D006801:Humans; D007252:Influenza Vaccines / Q000494:pharmacology*; D007251:Influenza, Human / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control*; D009656:North America / Q000453:epidemiology; D017063:Outcome Assessment, Health Care
D007252:Influenza Vaccines