title: Trace element levels in whole blood and serum from Swedish adolescents.
abstract: Blood and serum samples from 372 15-year-old adolescents were collected in two cities in Sweden and analyzed by inductively coupled plasma mass spectrometry (ICP-MS). The objective was to (1) determine the levels of 13 elements in blood and serum from the teenagers; and (2) for each element, investigate the correlation between the concentrations in blood and serum. The concentrations in blood and serum were generally in line with that usually reported for the essential elements Co, Cu, Zn and Se, and generally low for the 'non-essential' elements Cd, Hg, Pb. The median concentrations were in blood and serum, respectively: of Co 0.31 and 0.48 microg/l, Cu 0.92 and 1.0 mg/l, Zn 6.1 and 0.99 mg/l, Se 110 and 100 microg/l, Rb 2.8 and 0.24 mg/l, Hg 1.1 and 0.44 microg/l, Pb 16 and 0.33 microg/l. The median concentration of W in blood was <0.2 microg/l (below the detection limit) and in serum 0.087 microg/l. The median concentrations of Cd, Rh, Pd, Pt and Tl were below the detection limits. Statistically significant correlations were found between the concentrations in blood and serum for Co, Cu, Zn, Se, Rb, W, Hg and Pb. The levels presented in this study constitute baseline levels or levels generally not exceeded in adolescents for 13 elements, including essential, ubiquitous toxic, and rare elements.
authors.affiliation: Department of Pharmacology and Toxicology, Swedish University of Agricultural Sciences, Uppsala. ebba.barany@farmtox.slu.se
authors.forename: Ebba
authors.initials: E
authors.lastname: Bárány
authors.forename: Ingvar A
authors.initials: IA
authors.lastname: Bergdahl
authors.forename: Lars-Eric
authors.initials: LE
authors.lastname: Bratteby
authors.forename: Thomas
authors.initials: T
authors.lastname: Lundh
authors.forename: Gösta
authors.initials: G
authors.lastname: Samuelson
authors.forename: Andrejs
authors.initials: A
authors.lastname: Schütz
authors.forename: Staffan
authors.initials: S
authors.lastname: Skerfving
authors.forename: Agneta
authors.initials: A
authors.lastname: Oskarsson
mesh_terms: D000293:Adolescent; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D019216:Metals, Heavy / Q000097:blood*; D013548:Sweden; D014131:Trace Elements / Q000097:blood*; D014505:Urban Population
chemical_list: D019216:Metals, Heavy; D014131:Trace Elements