title: Vitamin A, vitamin E and carotenoid status and metabolism during ageing: functional and nutritional consequences (VITAGE PROJECT).
abstract: Among the nutritional factors contributing to maintain health during ageing, fat-soluble vitamins (FSV) are crucial to protect against free radical-generated degenerative processes or impaired efficiency of the immune system. However, no sound scientific evidence is able to confirm specific dietary needs in vitamin A, vitamin E and carotenoids for the healthy elderly. VITAGE project aims at providing such evidence by undertaking studies on male volunteers from 3 European countries, aged between 20-75 years. Biomarkers and variables related to status, metabolism and functions will be measured either in steady-state conditions, or during dietary depletion and repletion in FSV. Original, yet already developed, methodologies will provide clear information about the physiological characteristics of vitamin A, vitamin E and carotenoids. Simultaneously, marketing opportunities for FSV-enriched dietetic foods, specifically designed for the elderly will be determined. The scientific and economical evidence obtained in this project will provide the basis to implement a EU nutritional policy towards the elderly and to develop a new sector of dietetic food products.
authors.affiliation: INRA. UMMM. CRNH, Centre de Theix, Saint-Genès Champanelle, France.
authors.forename: E
authors.initials: E
authors.lastname: Rock
authors.forename: B M
authors.initials: BM
authors.lastname: Winklhofer-Roob
authors.forename: J
authors.initials: J
authors.lastname: Ribalta
authors.forename: M
authors.initials: M
authors.lastname: Scotter
authors.forename: M P
authors.initials: MP
authors.lastname: Vasson
authors.forename: J
authors.initials: J
authors.lastname: Brtko
authors.forename: R
authors.initials: R
authors.lastname: Brigelius-Flohe
authors.forename: A
authors.initials: A
authors.lastname: Bronner
authors.forename: V
authors.initials: V
authors.lastname: Azaïs-Braesco
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D002338:Carotenoids / Q000378:metabolism*; D005062:European Union; D006801:Humans; D008297:Male; D008875:Middle Aged; D018673:Nutrition Policy; D009751:Nutritional Requirements; D009752:Nutritional Status; D014801:Vitamin A / Q000378:metabolism*; D014810:Vitamin E / Q000378:metabolism*
chemical_list: D014801:Vitamin A; D014810:Vitamin E; D002338:Carotenoids