[132 grams of tamoxifen: ultrasonographic and MRI appearance of endometrial carcinoma].
Endometrial carcinoma is a rare iatrogenic complication due to the adverse estrogenic like effect of Tamoxifen on the uterine mucosa. We report the delayed case of an endometrial carcinoma after an unusual twleve year long daily administration of Tamoxifen (cumulative dose = 131 g). Endovaginal contrast ultrasound examination (Levovist, Schering, Germany) and MRI appearances are described.
Marcy
P Y
PY
Service de Radiologie, Centre Antoine Lacassagne, 33 avenue de Valombrose, 06189 Nice. pierre-yves.marcy@cal.nice.fnclcc.fr
Largillier
R
R
Bailet
C
C
Hannoun-Lévi
J M
JM
Magné
N
N
D000230:Adenocarcinoma / Q000139:chemically induced* / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000009:adverse effects*; D001918:Brachytherapy; D003131:Combined Modality Therapy; D003287:Contrast Media; D016889:Endometrial Neoplasms / Q000139:chemically induced* / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007049:Iatrogenic Disease; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011134:Polysaccharides; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D013629:Tamoxifen / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors; D014463:Ultrasonography
D018931:Antineoplastic Agents, Hormonal; D003287:Contrast Media; D011134:Polysaccharides; D013629:Tamoxifen; C059891:SHU 508