title: Symptomatic reversal of peripheral neuropathy in patients with diabetes.
abstract: Forty-nine consecutive subjects with established diabetic peripheral neuropathy were treated with monochromatic near-infrared photo energy (MIRE) to determine if there was an improvement of sensation. Loss of protective sensation characterized by Semmes-Weinstein monofilament values of 4.56 and above was present in 100% of subjects (range, 4.56 to 6.45), and 42 subjects (86%) had Semmes-Weinstein values of 5.07 or higher. The ability to discriminate between hot and cold sensation was absent (54%) or impaired (46%) in both groups prior to the initiation of MIRE treatment. On the basis of Semmes-Weinstein monofilament values, 48 subjects (98%) exhibited improved sensation after 6 treatments, and all subjects had improved sensation after 12 treatments. Therefore, MIRE may be a safe, drug-free, noninvasive treatment for the consistent and predictable improvement of sensation in diabetic patients with peripheral neuropathy of the feet.
authors.affiliation: The Medical Center of Aurora, Aurora, CO, USA.
authors.forename: Alan B
authors.initials: AB
authors.lastname: Kochman
authors.forename: Dale H
authors.initials: DH
authors.lastname: Carnegie
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Burke
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003929:Diabetic Neuropathies / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D010789:Phototherapy / Q000379:methods; D011446:Prospective Studies; D012677:Sensation; D016896:Treatment Outcome