Severe pulmonary hypertensive vascular disease in two newborns with aneurysmal vein of galen.
Arteriovenous malformation of the vein of Galen (AVG) is a rare entity in the newborn with a high morbidity and mortality. We present two cases of fatal AVG with persistent pulmonary hypertension of the newborn and significant pulmonary hypertension documented by autopsy histopathology. The pathophysiology is reviewed and a proposed mechanism of the association between AVG and pulmonary hypertension is discussed.
Dahdah
N S
NS
Department of Pediatrics, Division of Cardiology, MetroHealth Medical Center, Case Western Reserve University, 2500 MetroHealth Drive, Cleveland, OH 44109, USA. ndahdah@pol.net
Alesseh
H
H
Dahms
B
B
Saker
F
F
D002550:Cerebral Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D007231:Infant, Newborn; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D016216:Ultrasonography, Prenatal