A unique group of self-splicing introns in bacteriophage T4.
We describe in this review, the salient splicing features of group I introns of bacteriophage T4 and propose, a hypothetical model to fit in the self-splicing of nrdB intron of T4 phage. Occurrence of non-coding sequences in prokaryotic cells is a rare event while it is common in eukaryotic cells, especially the higher eukaryotes. Therefore, T4 bacteriophage can serve as a good model system to study the evolutionary aspects of splicing of introns. Three genes of T4 phage were found to have stretches of non-coding sequences which belonged to the group IA type introns of self-splicing nature.
Khan
A U
AU
Interdisciplinary Biotechnology Unit, A M U Aligarh, India. asaduk@usa.net
Ajamaluddin
M
M
Ahmad
M
M
D017122:Bacteriophage T4 / Q000235:genetics*; D001483:Base Sequence; D007438:Introns / Q000235:genetics*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012326:RNA Splicing / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics*
D012367:RNA, Viral