Effects of inhaled corticosteroids on growth in asthmatic children.
This article presents a brief review of the effects of inhaled corticosteroids on growth in children with asthma. All currently available inhaled corticosteroids, where there is adequate data, have been shown to cause significant growth suppression in children in a dose-dependent manner. It is now apparent that there are differences in the growth-suppressive effects of different corticosteroids. Recent evidence confirms that the growth-suppressive effects are short lived and that, at conventional doses, inhaled corticosteroids do not affect final attained adult height.
Creese
K H
KH
Cystic Fibrosis/Respiratory Unit, Department of Child Health, University Hospital of Wales, Cardiff CF14 4XW, UK.
Doull
I J
IJ
D000280:Administration, Inhalation; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D002669:Child Welfare; D004305:Dose-Response Relationship, Drug; D006128:Growth / Q000187:drug effects*; D006801:Humans; D013997:Time Factors; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones