title: Sonographic diagnosis of spina bifida at 12 weeks: heading towards indirect signs.
abstract: Retrospective examination of ultrasound images obtained at 12 weeks of gestation in two fetuses with spina bifida demonstrated retraction of the frontal bones, resulting in an acorn-shaped head, the cerebral peduncles appearing parallel to each other. These craniocerebral signs may improve the accuracy of first-trimester diagnosis of spina bifida by sonography.
authors.affiliation: Department of Obstetrics and Gynaecology, Centre Hospitalier de Poissy St-Germain, Poissy, France.
authors.forename: O
authors.initials: O
authors.lastname: Buisson
authors.forename: B
authors.initials: B
authors.lastname: De Keersmaecker
authors.forename: M V
authors.initials: MV
authors.lastname: Senat
authors.forename: J P
authors.initials: JP
authors.lastname: Bernard
authors.forename: G
authors.initials: G
authors.lastname: Moscoso
authors.forename: Y
authors.initials: Y
authors.lastname: Ville
mesh_terms: D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016135:Spinal Dysraphism / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal