title: A laser Doppler study of gingival blood flow variations following periosteal stimulation.
abstract: OBJECTIVE
  Evaluation of the modifications occurring in human gingival blood flow following periosteal stimulation.
  
  
  METHODS
  Laser Doppler was used to measure the gingival blood flow (GBF). The reproducibility of the technique was validated by comparing measures made at intervals of 1 week. Sensitivity was verified by recording GBF before and after injection of an anesthetic containing a vasoconstrictor. Finally, 12 patients were subjected to GBF measurements before and 8 days after periosteal stimulation prior to gingival grafting.
  
  
  RESULTS
  The laser Doppler accurately measured GBF. Measurements made at day 0 and day 7 were not statistically different (p=0.60). After injection of an anesthesic solution containing vasoconstrictor, the laser Doppler recorded a sharp decrease of the GBF (p=0.04). The patient that underwent periosteal stimulation showed statistically significant increases (p=0.02) in GBF before and 1 week post-stimulation.
  
  
  CONCLUSIONS
  Periosteal stimulation induces significant increases in the GBF after 1 week.
authors.affiliation: Department of Periodontics, Faculty of Dental Health, University Henry Poincaré of Nancy, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Ambrosini
authors.forename: Sabine
authors.initials: S
authors.lastname: Cherene
authors.forename: Neal
authors.initials: N
authors.lastname: Miller
authors.forename: Michel
authors.initials: M
authors.lastname: Weissenbach
authors.forename: Jacques
authors.initials: J
authors.lastname: Penaud
mesh_terms: D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage; D004837:Epinephrine / Q000008:administration & dosage; D005260:Female; D005881:Gingiva / Q000098:blood supply* / Q000637:transplantation; D006801:Humans; D007267:Injections; D017078:Laser-Doppler Flowmetry; D008297:Male; D008875:Middle Aged; D010521:Periosteum / Q000293:injuries*; D010865:Pilot Projects; D011677:Punctures / Q000009:adverse effects; D012039:Regional Blood Flow / Q000502:physiology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D013997:Time Factors; D014662:Vasoconstrictor Agents / Q000008:administration & dosage
chemical_list: D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D004837:Epinephrine