Antidiabetic principles of natural medicines. V. Aldose reductase inhibitors from Myrcia multiflora DC. (2): Structures of myrciacitrins III, IV, and V.
Following the characterization of myrciacitrins I and II and myrciaphenones A and B, three new flavanone glucosides, myrciacitrins III, IV, and V, were isolated from the leaves of Brazilian Myrcia multiflora. The structures of new myrciacitrins were elucidated on the basis of physicochemical and chemical evidence. Myrciacitrins were found to show potent inhibitory activity on aldose reductase.
Matsuda
Hisashi
H
Kyoto Pharmaceutical University, Japan.
Nishida
Norihisa
N
Yoshikawa
Masayuki
M
D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors*; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology*; D015394:Molecular Structure; D029590:Myricaceae / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry
D004791:Enzyme Inhibitors; D005419:Flavonoids; D007004:Hypoglycemic Agents; D000449:Aldehyde Reductase