Susceptibilities of Mycobacterium marinum to gatifloxacin, gemifloxacin, levofloxacin, linezolid, moxifloxacin, telithromycin, and quinupristin-dalfopristin (Synercid) compared to its susceptibilities to reference macrolides and quinolones.
The susceptibility pattern of Mycobacterium marinum was determined. Quinupristin-dalfopristin and telithromycin were less active than clarithromycin. Linezolid showed good antimicrobial activity at clinically achievable concentrations. Gatifloxacin, levofloxacin, and moxifloxacin displayed activities similar to those of ciprofloxacin. Gemifloxacin was less active. The Etest method showed variable agreement with the reference method.
Bråbäck
Martin
M
Department of Medical Microbiology, Lund University, University Hospital, S-205 02 Malmö, Sweden.
Riesbeck
Kristian
K
Forsgren
Arne
A
D000081:Acetamides / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024841:Fluoroquinolones; D006801:Humans; D048628:Ketolides; D000069349:Linezolid; D018942:Macrolides; D008826:Microbial Sensitivity Tests; D009165:Mycobacterium Infections, Nontuberculous / Q000382:microbiology; D019910:Mycobacterium marinum / Q000187:drug effects* / Q000254:growth & development; D023303:Oxazolidinones / Q000494:pharmacology*; D014769:Virginiamycin / Q000031:analogs & derivatives / Q000494:pharmacology*
D000081:Acetamides; D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D048628:Ketolides; D018942:Macrolides; D023303:Oxazolidinones; D014769:Virginiamycin; C113825:quinupristin; D000069349:Linezolid; C106791:telithromycin