title: Hematological effects of high dose of cortisol on the carp (Cyprinus carpio L.): cortisol effect on the carp blood.
abstract: The level of circulating cortisol and peripheral blood parameters were determined in carp age 2 years (K(2)) 24, 72, and 216 h after a single intraperitoneal injection of a high dose (200 mg x kg(-1) body wt) of hydrocortisone. The most striking effect of cortisol was manifest as a significant change in the percentage composition of leukocytes, whose number per unit volume of blood remained relatively constant. A profound lymphopenia and eosinopenia were compensated for in the general balance by an increased number of circulating promyelocytes and myelocytes as well as metamyelocytes and mature polymorphonuclear neutrophilic granulocytes. The results and their possible reasons are discussed on the background of literature data.
authors.affiliation: Department of Animal Physiology, Zoological Institute, Wrocław University, Cybulskiego 30, 50-205, Wrocław, Poland. wojtasz@biol.uni.wroc.pl
authors.forename: J
authors.initials: J
authors.lastname: Wojtaszek
authors.forename: D
authors.initials: D
authors.lastname: Dziewulska-Szwajkowska
authors.forename: M
authors.initials: M
authors.lastname: Lozińska-Gabska
authors.forename: A
authors.initials: A
authors.lastname: Adamowicz
authors.forename: A
authors.initials: A
authors.lastname: Dzugaj
mesh_terms: D000818:Animals; D002347:Carps / Q000097:blood*; D004804:Eosinophils; D006098:Granulocytes; D006412:Hematopoietic Stem Cells; D006854:Hydrocortisone / Q000008:administration & dosage* / Q000097:blood* / Q000494:pharmacology; D007274:Injections, Intraperitoneal; D007958:Leukocyte Count; D007962:Leukocytes / Q000187:drug effects*; D008214:Lymphocytes; D009504:Neutrophils
chemical_list: D006854:Hydrocortisone