Ultrapulse CO2 used for the successful treatment of basal cell carcinomas found in patients with basal cell nevus syndrome.
BACKGROUND
Basal cell nevus syndrome (BCNS) is an inherited condition marked by multiple basal cell carcinomas (BCCs) associated with several other abnormalities. Various treatment modalities have been used to eradicate these tumors. However, recurrences and scarring limit their use.


OBJECTIVE
To evaluate the treatment of multiple BCCs associated with BCNS.


METHODS
We describe three cases of BCNS in which multiple BCCs were effectively treated with ultrapulse CO2 laser. Postoperative Mohs micrographic surgical sections (thin sections looking for residual tumor) verified complete histologic clearance of the tumors.


RESULTS
All three patients were effectively treated with ultrapulse CO2 laser. Minimal scarring was noted at follow-up.


CONCLUSIONS
Ultrapulse CO2 laser can be used to effectively treat small BCCs in low-risk areas associated with BCNS with minimal posttreatment scarring.
Nouri
Keyvan
K
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA. Knouri@med.miami.edu
Chang
Attica
A
Trent
Jennifer T
JT
Jiménez
Gloria P
GP
D000293:Adolescent; D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000532:radiotherapy*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000532:radiotherapy*; D012878:Skin Neoplasms / Q000532:radiotherapy*