title: [Morphological validation of peloidobalneotherapy intensification in patients with duodenal ulcer].
abstract: OBJECTIVE
  To study effectiveness of short courses of intensive peloidobalneotherapy in duodenal ulcer (DU).
  
  
  METHODS
  Esophagogastroduodenoscopy and biopsy before and after the treatment course were made in 124 DU patients. Depending on timing of moor applications, pine and pearl baths, the patients were divided into 2 groups. Patients of group 1 received procedures daily with interval 4-5 hours (intensive course), patients of group 2 were treated each other day.
  
  
  RESULTS
  3-4 weeks of the treatment produced a response in both groups but in group 2 there were no signs of active inflammation in gastric and duodenum mucosa. 2 years later, patients of group 1 had histological evidence of chronic inflammation exacerbation. The latter was absent in group 2.
  
  
  CONCLUSIONS
  An intensive course of peloidobalneotherapy results in attenuation of chronic gastroduodenal inflammation in DU patients.
authors.forename: V S
authors.initials: VS
authors.lastname: Petrakova
authors.forename: O I
authors.initials: OI
authors.lastname: Ugol'nikova
authors.forename: N G
authors.initials: NG
authors.lastname: Kritskaia
authors.forename: E I
authors.initials: EI
authors.lastname: Beloborodova
mesh_terms: D001452:Balneology / Q000379:methods*; D004381:Duodenal Ulcer / Q000473:pathology / Q000628:therapy*; D006801:Humans