[Study of stress reactivity in offspring of first-generation rats after irradiation of one or both parents].
Three-month old white mongrel rats (F0) were exposed to X-rays (single exposure dose 1 Gy). Their offsprings F1 were subjected to acute hypokinezia for 60 minutes at different periods of life. The changes of the hormonic status were revealed in males F1; in females F1 deviations were not observed. The stress reactivity of males F1 depended on which of the parents was exposed to radiation. After irradiation of both parents or males F0 only the hyporeactivity in senile age was more pronounced their in control animals of the same age. After irradiation of females F0 only a response to stress in male offsprings F1 corresponded to the control values.
Mizina
T Iu
TIu
Research Institute of Biology and Biophysics, Tomsk State University, Tomsk, 634050 Russia. sit@res.tsu.ru
D000367:Age Factors; D000818:Animals; D005260:Female; D018476:Hypokinesia; D008297:Male; D018811:Maternal Exposure; D018812:Paternal Exposure; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental; D011839:Radiation, Ionizing; D051381:Rats; D012737:Sex Factors; D013312:Stress, Physiological / Q000209:etiology / Q000503:physiopathology*; D013997:Time Factors