Intracranial meningeal melanocytoma associated with ipsilateral nevus of Ota. Case report.
In this report, the authors review the case of a man with a neurocutaneous syndrome. He presented with an intracerebral melanocytoma associated with a blue nevus of the scalp; its location and its appearance during childhood supported the diagnosis of a nevus of Ota. Meningeal melanocytomas are increasingly being diagnosed, but remain rare. Primary meningeal malignant melanoma is the first differential diagnosis to eliminate. Despite their common embryonic origin. the association of a melanocytoma with a nevus of Ota is rare. A nevus of Ota exhibits the same melanocytic proliferation and affects the trigeminal nerve territory. An ocular effect is not always observed. In contrast to an ocular lesion, a nevus of Ota rarely transforms into a malignant melanoma. It is found only among caucasians. During 4 years of follow-up review after surgery, the patient remained asymptomatic. Other than antiepileptic therapy, he received no complementary treatment and cerebral imaging revealed no evidence of recurrence.
Piercecchi-Marti
Marie-Dominique
MD
Department of Forensic Medicine, Centre Hospitalier Régional et Universitaire de Marseille, Timone, France. mpiercecchi@ap-hm.fr
Mohamed
Hicham
H
Liprandi
Agnes
A
Gambarelli
Daniele
D
Grisoli
Francois
F
Pellissier
Jean-François
JF
D000328:Adult; D001706:Biopsy; D062109:Dermatologic Surgical Procedures; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008578:Meninges / Q000473:pathology / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D020752:Neurocutaneous Syndromes / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009507:Nevus of Ota / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery