title: Transmetalation of palladium enolate and its application in palladium-catalyzed homocoupling of alkynes: a room-temperature, highly efficient route to make diynes.
abstract: A novel pathway for the homocoupling reaction has been achieved using a similar protocol as the cross-coupling reaction. Ethyl bromoacetate is chosen to initiate the coupling reaction through oxidative addition to a Pd(0) species, and an PdBr(enolate) intermediate is formed. This intermediate can undergo double transmetalation with an alkynyl copper reagent, and reductive elimination produces a variety of diynes in high yields.
authors.affiliation: Department of Chemistry, Pennsylvania State University, 152 Davey Laboratory, University Park, Pennsylvania 16802, USA.
authors.forename: Aiwen
authors.initials: A
authors.lastname: Lei
authors.forename: Manisha
authors.initials: M
authors.lastname: Srivastava
authors.forename: Xumu
authors.initials: X
authors.lastname: Zhang