title: Sperm motility in the semen analysis affects the outcome of superovulation intrauterine insemination in the treatment of infertile Asian couples with male factor infertility.
abstract: OBJECTIVE
  To ascertain the relationship between the initial and unprocessed sperm parameters and pregnancy rates in SOIUI, for Asian couples with male factor infertility.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  A large government tertiary-care women's hospital with 15,000 deliveries per year.
  
  
  METHODS
  One thousand four hundred and seventy nine couples undergoing 2846 cycles of SOIUI.
  
  
  METHODS
  All couples enrolled in the SOIUI programme were analysed, comparing initial sperm parameters and the post-processed total motile sperm, against pregnancy rates per cycle.
  
  
  METHODS
  Pregnancy rates in relation to initial sperm parameters and post-processed total motile sperm.
  
  
  RESULTS
  Ninety-three percent of the couples had male factor infertility. The average normal forms for these men was 14.7%. Overall pregnancy rate was 12.1% per completed SOIUI cycle. We found a significant drop in pregnancy rates if the percentage of motile sperms in the unprocessed sperm sample fell below 30%. We also found that insemination of at least 1 million motile sperm resulted in a significant increase in pregnancy rates.
  
  
  CONCLUSIONS
  We recommend SOIUI as an effective treatment of suitable couples with male infertility, before embarking on IVF. However, if the initial percentage of motile sperm fell below 30%, or if after processing, the total motile sperm count was fewer than 1 million, these couples should consider in vitro fertilisation.
authors.affiliation: Reproductive Medicine Department, Kandang Kerbau Women's and Children's Hospital, Singapore.
authors.forename: Vincent M S
authors.initials: VM
authors.lastname: Lee
authors.forename: Joycelyn S Y
authors.initials: JS
authors.lastname: Wong
authors.forename: Sheila K E
authors.initials: SK
authors.lastname: Loh
authors.forename: Noel K Y
authors.initials: NK
authors.lastname: Leong
mesh_terms: D000328:Adult; D001208:Asia / Q000208:ethnology; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000208:ethnology / Q000628:therapy*; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D011247:Pregnancy / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012661:Semen / Q000737:chemistry*; D013076:Sperm Count; D013081:Sperm Motility / Q000502:physiology*; D013480:Superovulation / Q000208:ethnology / Q000502:physiology*