title: Depolymerization of N-succinyl-chitosan by hydrochloric acid.
abstract: N-Succinyl-chitosan (1) was depolymerized with 7.5 M aqueous HCl at room temperature or 3.3 M aqueous HCl at 40 degrees C and the molecular weights (MW) of the products were determined by size-exclusion chromatography-multi angle light scattering (SEC-MALS) and their viscometric features were investigated. The intrinsic viscosity ([eta]) obtained at the concentration of 0.1-0.3% (w/v) in saline showed a linear relationship between log[eta] and log MW, which provided the coefficients in the Mark-Houwink equation.
authors.affiliation: Department of Drug Delivery Research, Hoshi University, Tokyo, Japan. d711@hoshi.ac.jp
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kato
authors.forename: Hiraku
authors.initials: H
authors.lastname: Onishi
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Machida
mesh_terms: D001704:Biopolymers / Q000737:chemistry* / Q000302:isolation & purification; D002686:Chitin / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification; D048271:Chitosan; D002850:Chromatography, Gel / Q000379:methods; D019281:Dimerization; D006851:Hydrochloric Acid / Q000737:chemistry*; D008027:Light; D008970:Molecular Weight; D012542:Scattering, Radiation; D012996:Solutions / Q000737:chemistry; D014783:Viscosity
chemical_list: D001704:Biopolymers; C118639:N-succinyl-chitosan; D012996:Solutions; D002686:Chitin; D048271:Chitosan; D006851:Hydrochloric Acid