title: A versatile structural domain analysis server using profile weight matrices.
abstract: The WEB tool "AnDom" assigns to a given protein sequence all experimentally determined structural domains contained within it, including multidomain and large proteins. The server uses profile specific matrices from custom generated multiple sequence alignments of all known SCOP domains (SCOP version 1.50). Prediction time is short allowing numerous applications for structural genomics including investigation of complex eucaryotic protein families. The WWW server is at http://www.bork.embl-heidelberg.de/AnDom, and profiles can be downloaded at ftp.bork.embl-heidelberg.de/pub/users/ schmidt/AnDom.
authors.affiliation: EMBL, Postfach 102209, D-69012 Heidelberg, Germany.
authors.forename: Steffen
authors.initials: S
authors.lastname: Schmidt
authors.forename: Peer
authors.initials: P
authors.lastname: Bork
authors.forename: Thomas
authors.initials: T
authors.lastname: Dandekar
mesh_terms: D000595:Amino Acid Sequence; D030562:Databases, Protein; D008969:Molecular Sequence Data; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D017386:Sequence Homology, Amino Acid
chemical_list: D011506:Proteins