title: Delayed-interval delivery in twin pregnancies.
abstract: OBJECTIVE
  To report on pregnancy outcome in six twin pregnancies with delayed-interval delivery in a single maternal-fetal medicine practice.
  
  
  METHODS
  All cases of attempted delayed-interval delivery from January 1988 to August 2000 in a single maternal-fetal medicine practice were retrospectively reviewed. Patients were managed with a treatment protocol that included rescue cerclage after delivery of the first born twin, antibiotics, corticosteroids and tocolysis.
  
  
  RESULTS
  Five of the six twin gestations resulted in viable birth of the second-born twin. One pregnancy had loss of both fetuses before viability. All first-born twins were nonviable. The median pregnancy prolongation achieved following delivery of the first-born, nonviable twin was 93 days, with a range of 23-153. Three of the five viable, second-born twins had a neonatal intensive care nursery stay of 3, 4 and 35 days (mean, 8.4). No infant required a ventilator.
  
  
  CONCLUSIONS
  Based on our analysis of these six cases, the pregnancy prolongation gained resulted in a clinically significant benefit to the second-born twin, without significant morbidity in the mother.
authors.affiliation: Department of Maternal-Fetal Medicine, Shady Grove Adventist Hospital, 9707 Medical Center Drive, Suite 230, Rockville, MD 20850, USA.
authors.forename: Sheri L
authors.initials: SL
authors.lastname: Hamersley
authors.forename: Suzanne K
authors.initials: SK
authors.lastname: Coleman
authors.forename: Niki K
authors.initials: NK
authors.lastname: Bergauer
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Bartholomew
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Pinckert
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D023802:Cerclage, Cervical; D002985:Clinical Protocols; D003131:Combined Modality Therapy; D036861:Delivery, Obstetric / Q000379:methods*; D005260:Female; D005328:Fetal Viability; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013997:Time Factors; D015149:Tocolytic Agents / Q000627:therapeutic use; D014427:Twins
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D015149:Tocolytic Agents