title: Leg ulcers.
abstract: Skin ulcers of the lower extremities have a chronic, relapsing course and often are difficult to manage. Leg ulcers remain a significant management challenge to health care professionals. This article focuses on the various causes of leg ulcers, with an emphasis on venous disease. Characteristic clinical findings and appropriate treatment options are discussed. Finally, the latest advances in the treatment of venous ulcers and their implications for clinical practice are emphasized.
authors.affiliation: Department of Dermatology and Skin Surgery, Roger Williams Medical Center, Providence, Rhode Island 02908, USA.
authors.forename: Dana
authors.initials: D
authors.lastname: Paquette
authors.forename: Vincent
authors.initials: V
authors.lastname: Falanga
mesh_terms: D003094:Collagen / Q000627:therapeutic use; D006801:Humans; D007871:Leg Ulcer / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D010808:Physical Examination; D017768:Skin, Artificial; D014689:Venous Insufficiency / Q000150:complications; D014945:Wound Healing
chemical_list: C117898:Apligraf; D003094:Collagen