ent-Kaurane and beyerane diterpenoids from Excoecaria agallocha.
The roots of Excoecaria agallocha yielded four new diterpenoids, ent-3 beta,20-epoxy-3 alpha,6 alpha-dihydroxykaur-16-ene (agallochin F) (1), 3beta,20-epoxy-3 alpha-hydroxybeyer-15-ene (agallochin G) (2), 3 beta,20:15R,16S-diepoxy-3 alpha-beyeranol (agallochin H) (3), and 3 beta,20-epoxy-3 alpha,6 alpha-dihydroxy-18-nor-beyer-15-ene (agallochin I) (4), along with three known derivatives, 2-acetoxy-1,15-beyeradiene-3,12-dione (5), 2-hydroxy-1,15-beyeradiene-3,12-dione (6), and ent-kauran-16 beta-ol-3-one. The structures of 1-4 were determined by spectroscopic (NMR and MS) data interpretation.
Anjaneyulu
Ammanamanchi S R
AS
School of Chemistry, Andhra University, Visakhapatnam-530 003, India. anjaneyuasr@yahoo.com
Rao
Vadali Lakshmana
VL
Sreedhar
Karanam
K
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D007194:India; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D004224:Diterpenes