Synthesis of marine sponge bisindole alkaloids dihydrohamacanthins.
[structure: see text] A convergent synthesis of the marine sponge bisindole alkaloids dihydrohamacanthins is described. The synthesis centers on the construction of 3,5- and 3,6-linked pyrazinones and their reduction to the requisite piperazinones with sodium cyanoborohydride.
Miyake
Fumiko Y
FY
Oregon State University, Department of Chemistry, Corvallis, Oregon 97331, USA.
Yakushijin
Kenichi
K
Horne
David A
DA
D000818:Animals; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011161:Porifera
D026121:Indole Alkaloids