The expression of gbx-2 during zebrafish embryogenesis.
Gbx-2 is a homeobox gene essential for normal development of the midbrain and the anterior hindbrain. Zebrafish gbx-2 shares an overall similarity of 67.8, 68.1, 60.6 and 66.5% in amino acid sequence to human, mouse, chick and Xenopus Gbx-2, respectively. The expression of zebrafish gbx-2 is initially, before the completion of epiboly, restricted to the prospective posterior midbrain. The expression remains detectable until the end of pharyngula period. The gbx-2 mRNA is also detected in the otic vesicles, the dorsoposterior telencephalon, the rostral branchial arches, the pronephric duct and median fin fold.
Su
Ying
Y
Protein Science Laboratory of the MOE, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, People's Republic of China.
Meng
Anming
A
D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000196:embryology*; D002642:Chick Embryo; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000096:biosynthesis*; D006801:Humans; D017403:In Situ Hybridization; D051379:Mice; D008969:Molecular Sequence Data; D016372:RNA, Antisense / Q000096:biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D014018:Tissue Distribution; D029867:Xenopus Proteins; D015027:Zebrafish; D029961:Zebrafish Proteins
C084958:GBX2 protein, human; C513180:Gbx2 protein, Xenopus; C513182:Gbx2 protein, mouse; D018398:Homeodomain Proteins; D016372:RNA, Antisense; D012333:RNA, Messenger; D029867:Xenopus Proteins; D029961:Zebrafish Proteins; C513181:gbx2 protein, zebrafish