Microbiologic evaluation of commercial probiotics.
OBJECTIVE
To evaluate contents of commercial probiotic products marketed for veterinary or human administration.


METHODS
Microbiologic culture assay.


METHODS
8 veterinary probiotics and 5 human probiotics.


METHODS
Quantitative bacteriologic culture was performed on all products, and isolates were identified via biochemical characteristics. Comparison of actual contents versus label claims was performed.


RESULTS
Label descriptions of organisms and concentrations accurately described the actual contents of only 2 of 13 products. Five veterinary products did not specifically list their contents. Most products contained low concentrations of viable organisms. Five products did not contain 1 or more of the stated organisms, and 3 products contained additional species. Some products contained organisms with no reported probiotic effects; some of these organisms could be pathogens.


CONCLUSIONS
Most commercial veterinary probiotic preparations are not accurately represented by label claims. Quality control appears to be poor for commercial veterinary probiotics.
Weese
J Scott
JS
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada.
D000818:Animals; D001419:Bacteria / Q000254:growth & development*; D015169:Colony Count, Microbial / Q000662:veterinary; D004348:Drug Labeling / Q000592:standards; D006801:Humans; D019936:Probiotics / Q000592:standards*; D011786:Quality Control