Leishmania (Viannia) spp. dissemination and tissue tropism in naturally infected dogs (Canis familiaris).
First evidence is presented for Leishmania (Viannia) spp. dissemination and tissue tropism in the domestic dog. Using PCR and histology, parasites were detected in the conjunctiva, lung, lymph nodes and ovaries of 2 naturally infected Peruvian dogs. The detection of parasites in the blood indicates that parasite dissemination to those organs may have been haematogenous.
Reithinger
Richard
R
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. rreithinger@yahoo.co.uk
Lambson
Bronwen E
BE
Barker
Douglas C
DC
Counihan
Helen
H
Espinoza
Canales Juan
CJ
González
Jamintong Sabino
JS
Davies
Clive R
CR
D000818:Animals; D004283:Dog Diseases / Q000469:parasitology*; D004285:Dogs; D005260:Female; D005355:Fibrosis / Q000469:parasitology / Q000662:veterinary; D016773:Leishmaniasis, Cutaneous / Q000469:parasitology / Q000662:veterinary*; D008099:Liver / Q000469:parasitology; D008198:Lymph Nodes / Q000469:parasitology; D010053:Ovary / Q000469:parasitology; D018512:Parasitemia / Q000175:diagnosis / Q000662:veterinary; D016133:Polymerase Chain Reaction / Q000379:methods / Q000662:veterinary; D013154:Spleen / Q000469:parasitology