Experiments with micro-organisms and human cell cultures in the Zond 5 and Zond 7 flights.
Lysogenic strains of Escherichia coli were exposed to space conditions aboard the flight of Zond 5 and Zond 7. Space flight factors appeared to affect the state of episome systems of bacteria, as judged by data obtained with F-Lac+ donor cells which also carried genetic markers for threonine and leucine. Observations on phage induction are discussed and compared with results obtained aboard Biosatellite 2. A number of monolayer cultures of human cells (HeLa cells, fibroblasts, and A-1 cells) were repeatedly exposed to the space environment. In one instance, HeLa 19 cells increased in size after exposure to space conditions, a change which appeared to be genetically stable. HeLa 19 cells which were carried on six separate space flights showed a higher viability than corresponding cultures which were exposed only once aboard Zond 5.
Zhukov-Verezhnikov
N N
NN
USSR.
Volkov
M N
MN
Maisky
I N
IN
Rybakov
N I
NI
Guberniev
M A
MA
Podoplelov
I I
II
Kulagin
A N
AN
Aniskin
E D
ED
Rybakova
K D
KD
Sharyi
N I
NI
Voronkova
I P
IP
Saxonov
P P
PP
Kopyev
V Y
VY
Antipov
V V
VV
Kozlov
V A
VA
Parfyonov
G P
GP
Orlovsky
V I
VI
D002468:Cell Physiological Phenomena; D048429:Cell Size; D002478:Cells, Cultured; D003359:Cosmic Radiation; D004926:Escherichia coli; D005347:Fibroblasts; D006367:HeLa Cells; D006801:Humans; D008940:Mitotic Index; D010957:Plasmids / Q000235:genetics / Q000502:physiology*; D013026:Space Flight; D014775:Virus Activation / Q000235:genetics / Q000502:physiology*; D014893:Weightlessness