title: Chloramphenicol in the 21st century.
abstract: Chloramphenicol use has declined in the UK, despite it remaining highly active against a wide range of bacteria. This article will review the activity, pharmacology, toxicology, uses and potential uses of chloramphenicol in an era of increasing antimicrobial resistance.
authors.affiliation: London and Newham NHS Trusts, Department of Medical Microbiology, Royal London Hospital, London E1 1BB.
authors.forename: David W
authors.initials: DW
authors.lastname: Wareham
authors.forename: Peter
authors.initials: P
authors.lastname: Wilson
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy*; D002701:Chloramphenicol / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D002702:Chloramphenicol Resistance; D006801:Humans; D011500:Protein Synthesis Inhibitors / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D011500:Protein Synthesis Inhibitors; D002701:Chloramphenicol