[Metastatic gastric calcifications and bronchial neuroendocrine tumor].
We report the case of a 38 year-old man admitted for the treatment of a neuroendocrine carcinoma of the lung with multiple bone metastases. At the diagnosis, the serum biochemistry revealed an evidence of malignant hypercalcemia with acute renal impairment. At this point, a Tc 99-m MDP bone scan was performed and showed intense uptake throughout the gastric walls. The patient underwent a repeat bone scan after normalization of biochemistry; no more abnormal uptake was noted in the stomach. Hypercalcemia is an abnormality of the calcium metabolism frequently associated with malignant condition. Metastatic calcification results from increased accumulation of the calcium-phosphate salts in different tissues related to a local physiological alcalinity. Usually reversible, metastatic calcifications appear as various extraskeletal uptake at Tc 99-m MDP bone scan.
Schmitz
N
N
Service de pneumologie, Hôpital Lyautey, Hôpitaux Universitaires de Strasbourg.
Moreau
L
L
Pauli
G
G
Quoix
E
E
D000328:Adult; D001984:Bronchial Neoplasms / Q000473:pathology*; D002114:Calcinosis / Q000150:complications*; D006801:Humans; D008297:Male; D018358:Neuroendocrine Tumors / Q000556:secondary*; D013272:Stomach Diseases / Q000150:complications; D013274:Stomach Neoplasms / Q000150:complications* / Q000556:secondary*
Calcifications métastatiques gastriques et tumeur neuroendocrine bronchique.