Monobromoisophakellin, a new bromopyrrole alkaloid from the Caribbean sponge Agelas sp.
A detailed analysis of the chemical constituents of a Caribbean specimen of Agelas sp. was carried out. Four brominated compounds (1-4) were isolated and one of them was identified as a new bromopyrrole metabolite, monobromoisophakellin (1). The structure of 1 was determined using spectroscopic methods. All compounds were tested for their antifeedant activity against the Caribbean reef fish Thalassoma bifasciatum in an aquarium assay.
Assmann
Michael
M
Alfred-Wegener-Institut für Polar- und Meeresforschung, Bremerhaven, Germany.
Köck
Matthias
M
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D000818:Animals; D001966:Bromine / Q000032:analysis*; D017691:Caribbean Region; D002851:Chromatography, High Pressure Liquid; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry* / Q000302:isolation & purification
D000470:Alkaloids; D006576:Heterocyclic Compounds, 4 or More Rings; D011758:Pyrroles; C453921:monobromoisophakellin; D001966:Bromine