title: Congenital tumours and tumour-like lesions in domestic animals. 1. Cattle. A review.
abstract: The literature on congenital tumours and tumour-like lesions in calves was reviewed. Lesions were subdivided by their anatomical distribution and in addition also according to their histologic-pathogenetic nature. As a result of the latter method, four main groups were formed covering most of the lesions described so far: malignant lymphomas, mesotheliomas, hamartomas and embryonic tumours. Most lesions were of mesenchymal structure, carcinomas being extremely rare. Some findings may point to early genetic events, for instance twin calves both affected with malignant lymphoma and related calves with congenital facial neurofibromatosis. An external factor, asbestos, is suspected to play a role in the genesis of peritoneal mesotheliomatosis. The effects of congenital tumours on their hosts were often considerable: death by generalization (malignant lymphomas), ascites (mesotheliomas) or the growth of large abdominal tumours (nephroblastomas, mixed tumours). The latter two conditions often caused dystocia.
authors.affiliation: Faculty of Veterinary Medicine, Utrecht University, The Netherlands.
authors.forename: W
authors.initials: W
authors.lastname: Misdorp
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002417:Cattle; D002418:Cattle Diseases / Q000151:congenital* / Q000473:pathology*; D004781:Environmental Exposure; D020022:Genetic Predisposition to Disease; D009369:Neoplasms / Q000151:congenital* / Q000473:pathology / Q000662:veterinary*