abstract: The binding constants of the alpha(1)-foetoprotein of the rat embryo serum for oestrone and oestradiol-17beta have similar values, i.e. 1 x 10(8) M(-1) in average at 25 degrees. There is probably one binding site per mole of binding protein. The high alpha(1)-foetoprotein concentration in the rat embryo serum at 17-19 days of pregnancy explains the exceptionally high levels of fixation of the phenolsteroids by this serum.
authors.affiliation: Laboratoire de Biochimie médicale (Laboratoire Associé no. 87 du CNRS), U.E.R. des Saints-Pères, 45 rue des Saints-Pères, 75--6ème, Paris, France
authors.forename: L
authors.initials: L
authors.lastname: Savu
authors.forename: O
authors.initials: O
authors.lastname: Crepy
authors.forename: M A.
authors.initials: MA
authors.lastname: Guerin
authors.forename: E
authors.initials: E
authors.lastname: Nunez
authors.forename: F
authors.initials: F
authors.lastname: Engelmann
authors.forename: C
authors.initials: C
authors.lastname: Benassayag
authors.forename: M F.
authors.initials: MF
authors.lastname: Jayle
vernacular_title: Etude des constantes de liaison entre les oestrogenes et 1'alpha(1)-foetoproteine de rat.