[Study on the joint effects of acrylonitrile and alcohol in rats].
In order to learn the joint effects of acrylonitrile and alcohol, acrylonitrile(40 micrograms/g), alcohol (1000 micrograms/g) and the mixed liquid of the both (40, 1000 micrograms/g) were given to rats by gavage for 8 weeks. The results revealed the joint effects of acrylonitrile and alcohol. Hypofunction and structural lesion of hepatocyte were found in the rats. The numbers of white blood cells decreased remarkably in these two groups.
Xiao
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Division of Labor Health, Lanzhou Medical College, Lanzhou 730000, China.
D000181:Acrylonitrile / Q000633:toxicity*; D000818:Animals; D002273:Carcinogens / Q000633:toxicity*; D004357:Drug Synergism; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D007958:Leukocyte Count; D007964:Leukocytosis / Q000139:chemically induced; D008099:Liver / Q000473:pathology; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D002273:Carcinogens; D000431:Ethanol; D000181:Acrylonitrile