Non-bacterial thrombotic endocarditis.
A 63-year-old man presented with cachexia and confusion. He was found to have culture-negative endocarditis affecting his aortic valve. Despite treatment with broad-spectrum antibiotics and extensive investigation for an underlying cause, he suffered a large cerebral infarct and died. At post-mortem he was found to have non-bacterial thrombotic endocarditis and a metastatic signet-ring carcinoma.
Markides
V
V
National Heart & Lung Institute, Imperial College School of Medicine, Waller Cardiac Department, St Mary's Hospital, South Wharf Road, London W2 1NY, UK.
Nihoyannopoulos
P
P
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000473:pathology*; D017548:Echocardiography, Transesophageal; D004696:Endocarditis / Q000175:diagnosis / Q000209:etiology*; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis; D006801:Humans; D020767:Intracranial Thrombosis / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed