Evidence for a three stranded complex between poly I and poly C.
The conditions for the formation of a triple stranded semi-protonated complex between polyinosinic (poly (I)) and polycytidylic acid (poly (C)) are described. From potentiometric titrations and mixing curves, the stoichiometry and a phase-transition diagram is established between the partly protonated triple stranded and the unprotonated and completely protonated double helical complexes.
Thiele
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Service de Biochimie, Département de Biologie, Centre d'Etudes Nucléaires de Saclay, B.P. no. 2, 91 -, Gif-sur-Yvette, France
Guschlbauer
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