title: Cystic fibrosis in a child from Syria.
abstract: We describe a Syrian child with typical features of severe cystic fibrosis (CF) phenotype and a positive sweat test. DNA analysis confirmed homozygosity for the delta F508 mutation on chromosome 7. This report stresses the need to draw attention to and consider CF in Arab populations. The frequency and distribution of delta F508 in the Middle East are reviewed.
authors.affiliation: Department of Pediatrics, Hamad Medical Corporation, Doha, Qatar. atiqa@qatar.net.qa
authors.forename: A Abdul
authors.initials: AA
authors.lastname: Wahab
authors.forename: I A
authors.initials: IA
authors.lastname: Janahi
authors.forename: S
authors.initials: S
authors.lastname: Hebi
authors.forename: M
authors.initials: M
authors.lastname: al-Hamed
authors.forename: M
authors.initials: M
authors.lastname: Kambouris
mesh_terms: D018912:Arabs; D002897:Chromosomes, Human, Pair 7; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000208:ethnology; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D009154:Mutation; D013593:Syria
chemical_list: C505032:CFTR protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator