title: Predictors for success of needle revision of failing filtration blebs.
abstract: OBJECTIVE
  To assess the factors that can predict the success of external needle revision of failing blebs.
  
  
  METHODS
  Retrospective, nonrandomized, comparative case series.
  
  
  METHODS
  Forty-nine eyes of 43 patients who underwent a needle revision of a filtration bleb with 5-fluourouracil (5-FU) by one physician (SVLB) between August 1993 and December 1994.
  
  
  METHODS
  Needle revision of a failing filtration bleb using 5-FU.
  
  
  RESULTS
  The intraocular pressure, glaucoma medications, and any complications.
  
  
  RESULTS
  The risk ratio of fornix-based trabeculectomies compared with limbus-based trabeculectomies was 3.781; P = 0.047. The risk ratios for gender, race, type of glaucoma, lens status, previous surgery, antimetabolite used for the initial trabeculectomy, and preoperative bleb characteristics were not statistically different for any one group.
  
  
  CONCLUSIONS
  Fornix-based trabeculectomies were more likely to fail the needle revisions compared with limbus-based trabeculectomies. None of the five preneedling bleb characteristics showed a propensity toward success or failure. Other demographics such as gender, race, type of glaucoma, previous surgery, antimetabolite used for the initial trabeculectomy, and lens status were also not predictive for success.
authors.affiliation: Department of Ophthalmology, Rush Medical College of Rush University, Chicago, Illinois, USA.
authors.forename: Anjali S
authors.initials: AS
authors.lastname: Hawkins
authors.forename: Jessica K
authors.initials: JK
authors.lastname: Flanagan
authors.forename: Steven V L
authors.initials: SV
authors.lastname: Brown
mesh_terms: D000368:Aged; D000963:Antimetabolites / Q000627:therapeutic use; D003228:Conjunctiva / Q000601:surgery*; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D009339:Needles; D012086:Reoperation; D012189:Retrospective Studies; D012590:Sclera / Q000601:surgery*; D014130:Trabeculectomy / Q000379:methods*; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D000963:Antimetabolites; D005472:Fluorouracil