title: [Hypoxemia secondary to inferior vena cava return into left atrium].
abstract: The case of a right-to-left shunt-induced hypoxemia with an abnormal return of the inferior vena cava (AIVCR) into the left atrium (LA) is reported in a 30-year-old male with cyanosis and polycythemia. The chest X ray and the lung CT scan was normal. Spirometry was normal but the transfert-CO coefficient (KCO) was lowered. Hypoxemia was observed at rest and worsening during exercise. The alveolo-arterial oxygen tension difference under hyperoxia was increased (56 kPa). Contrast echocardiography (CEch) suggested the presence of an AIVCR with a right-to-left shunt only observed by the inferior route. The inferior vena cava (IVC) angiography and the magnetic resonance imaging demonstrated an AIVCR characterized by a direct drainage of IVC in the left atrium. The good tolerance can be explained by the association of AIVCR with an inter-auricular septal defect resulting in a left-to-right shunt which partially corrected the right-to-left shunt. After surgical treatment, arterial blood gases normalized, KCO remained low and CEch became negative.
authors.affiliation: Service d'Exploration Fonctionnelle Respiratoire, Hôpital Cardio-vasculaire et Pneumologique Louis Pradel, BP Lyon-Montchat, 69394 Lyon, France.
authors.forename: A H
authors.initials: AH
authors.lastname: Nassiri
authors.forename: B
authors.initials: B
authors.lastname: Gentil
authors.forename: M
authors.initials: M
authors.lastname: Barthelet
authors.forename: D
authors.initials: D
authors.lastname: Revel
authors.forename: J
authors.initials: J
authors.lastname: Ninet
authors.forename: J F
authors.initials: JF
authors.lastname: Cordier
authors.forename: J Y
authors.initials: JY
authors.lastname: Bayle
mesh_terms: D000015:Abnormalities, Multiple; D000328:Adult; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D008297:Male; D014682:Vena Cava, Inferior / Q000002:abnormalities*
vernacular_title: Hypoxémie secondaire à un abouchement de la veine cave inférieure dans l'oreillette gauche.