A case of contact urticaria syndrome due to di(2-ethylhexyl) phthalate (DOP) in work clothes.
We previously reported a case of contact urticaria syndrome (CUS) due to di(2-ethylhexyl) phthalate (DOP) in a polyvinyl chloride (PVC) grip on cotton gloves. The patient reported in this previous paper was careful not to have any contact with PVC products in his daily life or in his working environment. He discontinued the use of protective gloves with a PVC grip that was the cause of CUS. When working, he used cotton gloves without a PVC grip. We prescribed antihistamines which slightly improved his condition. However, when he wore work clothes while on duty, CUS relapsed. This condition was severe and made him feel anxious. When we advised him to wear a cotton shirt under his work clothes, the contact urticaria did not develop. We suspected that some component of the work clothes was the cause of his symptoms. A prick test with the extract solution of his work clothes showed a wheal and flare at the 15 min reading. The common component of the grip and the work clothes was found by analysis to be DOP.
Sugiura
Keiji
K
Department of Environmental Dermatology, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550 Japan.
Sugiura
Mariko
M
Hayakawa
Ritsuko
R
Shamoto
Mikihiro
M
Sasaki
Kazumi
K
D004051:Diethylhexyl Phthalate / Q000009:adverse effects* / Q000032:analysis; D017575:Gloves, Protective / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D010968:Plasticizers / Q000009:adverse effects*; D011143:Polyvinyl Chloride / Q000737:chemistry; D011481:Protective Clothing / Q000009:adverse effects*; D013577:Syndrome; D014581:Urticaria / Q000139:chemically induced*
D010968:Plasticizers; D011143:Polyvinyl Chloride; D004051:Diethylhexyl Phthalate