title: Multifocal intraocular lens implantation in prepresbyopic patients with unilateral cataract.
abstract: OBJECTIVE
  To evaluate the benefits of implantation of a zonal-progressive multifocal intraocular lens (IOL) in prepresbyopic patients with unilateral cataract.
  
  
  METHODS
  Prospective, nonrandomized, comparative trial.
  
  
  METHODS
  Ninety-five eyes of 95 prepresbyopic patients aged between 14 and 40 years with either multifocal or monofocal IOL implantation at two institutions and with more than 6 months follow-up.
  
  
  METHODS
  Temporal clear corneal phacoemulsification and foldable IOL implantation was performed in all eyes. In 54 patients, a zonal-progressive optic multifocal IOL (Array SA40-N, Allergan, Irvine, CA) was implanted, whereas 41 patients received a monofocal IOL and served as controls.
  
  
  RESULTS
  Preoperative patient demographics, mean postoperative spherical equivalent, astigmatism, and uncorrected and best-corrected distance visual acuities were similar in the two groups. Patients with a multifocal IOL achieved a significantly better uncorrected near visual acuity than patients with monofocal IOL (0.18 versus 0.37; P = 0.0001). With distance correction only, mean near visual acuity was 0.17 versus 0.43 (P = 0.0001). Best-corrected near visual acuity was 0.11 for both groups (P = 0.91), with +1.43 diopters (D) for the multifocal group and +2.35 D for the monofocal group (P = 0.0001). Spectacle dependency differed significantly between the two groups, with 21 patients (51%) of the monofocal group commonly requiring an additional plus add for near tasks compared with 5 patients (9%) in the multifocal group (P = 0.001). Stereopsis was superior in the multifocal group (P < 0.001), with 42 (77%) and 33 (61%) patients with a multifocal IOL responding positively to the Lang and Titmus tests, respectively. In the monofocal group; only 20 (48%) and 9 (22%) patients gave correct answers.
  
  
  CONCLUSIONS
  Multifocal IOL implantation is a viable alternative to monofocal pseudophakia in prepresbyopic patients with unilateral cataract.
authors.affiliation: Department of Ophthalmology, University of Cologne, Joseph-Stelzmannstrasse 9, 50931 Cologne, Germany.
authors.forename: Philipp C
authors.initials: PC
authors.lastname: Jacobi
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Dietlein
authors.forename: Christoph
authors.initials: C
authors.lastname: Lüke
authors.forename: Felix K
authors.initials: FK
authors.lastname: Jacobi
mesh_terms: D000293:Adolescent; D000328:Adult; D002386:Cataract / Q000150:complications*; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D018579:Patient Selection; D018918:Phacoemulsification; D011183:Postoperative Complications; D011305:Presbyopia / Q000150:complications* / Q000601:surgery*; D011446:Prospective Studies; D012449:Safety; D016896:Treatment Outcome; D014792:Visual Acuity