An autopsy case of intravascular lymphomatosis with dermatomyositis.
A 62-year-old man was admitted to hospital with general malaise, arthralgia, edema, and high-grade fever. He was diagnosed as dermatomyositis because of typical skin rashes and muscle weakness. His symptoms were improved by high-doses of prednisolone and cyclosporin A, with the exception of the skin rash over the back. High-grade fever developed again when tapering prednisolone. His condition deteriorated gradually. Paresthesia, hypothyroidism, metabolic acidosis, and disseminated intravascular coagulopathy occurred, and he died eight months after the first admission. Postmortem examination revealed intravascular proliferation of atypical mononuclear cells in the lumens of small vessels in all organs. Intravascular lymphomatosis (B cell type) was diagnosed.
Aoki
Akiko
A
First Department of Internal Medicine, Yokohama City University School of Medicine, Yokohama.
Okamura
Mayumi
M
Ueda
Atsuhisa
A
Ohno
Shigeru
S
Hagiwara
Eri
E
Tsuji
Takashi
T
Misumi
Midori
M
Kawachi
Kae
K
Sasaki
Tetsuo
T
Inoue
Yuko
Y
Ishigatsubo
Yoshiaki
Y
D001344:Autopsy; D003882:Dermatomyositis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014652:Vascular Diseases / Q000150:complications* / Q000473:pathology