[Pharmacodynamics study of suanzaoren decoction extracted by different technological process].
OBJECTIVE
To select the optimal technological process for Suanzaoren decoction.


METHODS
The effects of extracts from different technological processes on spontaneous motion and sleep time in mice induced by pentobarbital sodium (subthreshold dosage) were studied.


RESULTS
Both the decoction and 95% alcohol extract of Suanzaoren possess sedative and hypnotic effects.


CONCLUSIONS
Suanzaoren aqueous decoction was selected as the optimal technological process.
Li
Y
Y
Shenyang Pharmaceutical University, Shenyang 110016.
Wang
R
R
Chen
M
M
Wang
Z
Z
Bi
K
K
D000818:Animals; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D005260:Female; D005638:Fruit / Q000737:chemistry; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D010936:Plant Extracts / Q000302:isolation & purification / Q000493:pharmacokinetics*; D012890:Sleep / Q000187:drug effects; D013678:Technology, Pharmaceutical / Q000379:methods*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D006993:Hypnotics and Sedatives; D010936:Plant Extracts; C045965:suanzaorentang