title: The estimation of a preference-based measure of health from the SF-36.
abstract: This paper reports on the findings of a study to derive a preference-based measure of health from the SF-36 for use in economic evaluation. The SF-36 was revised into a six-dimensional health state classification called the SF-6D. A sample of 249 states defined by the SF-6D have been valued by a representative sample of 611 members of the UK general population, using standard gamble. Models are estimated for predicting health state valuations for all 18,000 states defined by the SF-6D. The econometric modelling had to cope with the hierarchical nature of the data and its skewed distribution. The recommended models have produced significant coefficients for levels of the SF-6D, which are robust across model specification. However, there are concerns with some inconsistent estimates and over prediction of the value of the poorest health states. These problems must be weighed against the rich descriptive ability of the SF-6D, and the potential application of these models to existing and future SF-36 data set.
authors.affiliation: Sheffield Health Economics Group, School of Health and Related Research, University of Sheffield, UK. j.e.brazier@sheffield.ac.uk
authors.forename: John
authors.initials: J
authors.lastname: Brazier
authors.forename: Jennifer
authors.initials: J
authors.lastname: Roberts
authors.forename: Mark
authors.initials: M
authors.lastname: Deverill
mesh_terms: D000203:Activities of Daily Living / Q000145:classification; D006302:Health Services Research; D006304:Health Status; D006801:Humans; D007407:Interviews as Topic; D017059:Models, Econometric; D017060:Patient Satisfaction / Q000191:economics* / Q000706:statistics & numerical data; D019057:Quality-Adjusted Life Years; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D006113:United Kingdom; D026712:Value of Life / Q000191:economics*