Worldwide incidence of multidrug-resistant tuberculosis.
Planning for tuberculosis (TB) control requires an assessment of the number and distribution of drug-resistant cases. This study used results of resistance surveys from 64 countries, together with data predictive of resistance rates from 72 others, to estimate the number of new multidrug-resistant (MDR) TB cases that occurred in 2000. By these methods, an estimated 273,000 (95% confidence limits, 185,000 and 414,000) new cases of MDR TB occurred worldwide in 2000, 3.2% of all new TB cases. The analysis provides the first comprehensive set of estimates of the MDR TB burden by country and globally.
Dye
Christopher
C
Communicable Diseases, World Health Organization, 1211 Geneva 27, Switzerland. dyec@who.int
Espinal
Marcos A
MA
Watt
Catherine J
CJ
Mbiaga
Cyrille
C
Williams
Brian G
BG
D006801:Humans; D015994:Incidence; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000453:epidemiology*