title: Rasmussen's encephalitis: a role for autoimmune cytotoxic T lymphocytes.
abstract: The present review describes advances in Rasmussen's encephalitis (also known as Rasmussen's syndrome), an unihemispheric intractable epileptic disease with persistent inflammation. Specific attention is given to the recent recognition of cytotoxicity by CD8+/granzyme-B-positive T lymphocytes as a new pathogenic mechanism of neuronal damage.
authors.affiliation: Brain Research Institute, Division of Neuroimmunology, University of Vienna, Vienna, Austria.
authors.forename: Jan
authors.initials: J
authors.lastname: Bauer
authors.forename: Christian G
authors.initials: CG
authors.lastname: Bien
authors.forename: Hans
authors.initials: H
authors.lastname: Lassmann
mesh_terms: D000906:Antibodies / Q000276:immunology; D020274:Autoimmune Diseases of the Nervous System / Q000276:immunology* / Q000473:pathology; D004660:Encephalitis / Q000209:etiology* / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D009474:Neurons / Q000378:metabolism; D018091:Receptors, AMPA / Q000276:immunology / Q000378:metabolism; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology* / Q000378:metabolism
chemical_list: D000906:Antibodies; D018091:Receptors, AMPA; C104723:glutamate receptor ionotropic, AMPA 3