[Ethological examination of Alzheimer's disease model rats treated with bushen yizhi decoction].
OBJECTIVE
To explore the ethological improving effect of Bushen Yizhi Decoction (BSYZD) in treating model rat of Alzheimer's disease (AD).


METHODS
Ethologic examination was carried out with Morris water maze on young, aged, AD model, Huperzine A treated and BSYZD treated groups of rats.


RESULTS
In the BSYZD treated group, the escape latency (EL) curve placed between that of the young, aged and AD model, Huperzine A treated group; the percentage of middle circle swim path, the 40 cm circle swimming time, and the platform-crossing times were not different from those in the normal aged group, but were different significantly as compared with the AD model group, P < 0.05.


CONCLUSIONS
BSYZD could ameliorate the behavior deficits of AD model.
Wang
H
H
Department of Neurobiology, Faculty of Anatomy, Shandong Medical University, Jinan 250012.
Lai
S
S
Sun
J
J
D000544:Alzheimer Disease / Q000523:psychology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D008297:Male; D018782:Maze Learning; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal