Falsely increased prostate-specific antigen concentration attributed to heterophilic antibodies.
We describe a 50-year-old man with a serum total prostatic-specific antigen concentration of 67.6 microg/L (reference range 0-4 microg/L) revealed as part of an annual health check programme. Clinical examination failed to identify any prostatic abnormality, and laboratory investigation indicated positive interference due to heterophilic antibodies.
Camacho
Tomás
T
Laboratorio Lema & Bandin, Vigo, Spain. atcamacho@teleline.es
Mora
Josefina
J
Segura
Ana
A
Guitián
Javier
J
Lema
Fernando
F
Bandín
Jesús
J
Rodríguez-Espinosa
José
J
D000910:Antibodies, Heterophile / Q000276:immunology*; D005189:False Positive Reactions; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood* / Q000276:immunology
D000910:Antibodies, Heterophile; D017430:Prostate-Specific Antigen