[The application of solid phase extraction for systematic toxicological analysis of abuse drugs].
A new column was developed in this research. It contains a proprietary bonded silica sorbent that exhibits mixed extraction mechanism. A single-column solid-phase extraction procedure was also developed for the screening of acidic, neutral and basic abuse drugs. The recovery of all 7 tested drugs exceeded 60%. The extraction mechanism for different abuse drugs on the new column was explored and was compared with on other columns. It is suggested that this column be effective in systematic toxicological analysis and better than other columns.
Wu
H
H
Institute of Forensic Science, PRC, Shanghai 200063.
Huang
Z
Z
Shen
M
M
D014150:Antipsychotic Agents / Q000032:analysis*; D001462:Barbital / Q000032:analysis; D002746:Chlorpromazine / Q000032:analysis; D003975:Diazepam / Q000032:analysis; D006993:Hypnotics and Sedatives / Q000032:analysis*
D014150:Antipsychotic Agents; D006993:Hypnotics and Sedatives; D001462:Barbital; D003975:Diazepam; D002746:Chlorpromazine