[Relationship between serum CA125 level and prognosis in the patients with uterine endometrial carcinoma].
OBJECTIVE
To study the relationship between serum CA125 level and prognosis of uterine endometrial carcinoma.


METHODS
The serum CA125 levels in 71 patients with uterine endometrial carcinoma were measured by using microparticle enzyme immunoassay. The relationship between preoperative CA125 levels and surgical pathologic staging, histologic classification, and other prognostic factors was investigated.


RESULTS
(1) The positive rate of serum CA125 in postmenopausal patients was significantly higher than in premenopausal patients. (2) The positive rate of serum CA125 was related to surgical pathologic staging. (3) Serum CA125 level was correlated not only with histological classification but also with other prognosis factors. (4) Increase of serum CA125 after operation predicted the possibility of relapse.


CONCLUSIONS
CA125 is a useful marker in predicting the prognosis of uterine endometrial carcinoma.
Xie
Z
Z
Department of Clinical Laboratory, Beijing Hospital, Beijing 100730, China.
Zhang
J
J
Tan
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018394:CA-125 Antigen / Q000097:blood*; D016889:Endometrial Neoplasms / Q000097:blood / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000097:blood; D017697:Premenopause / Q000097:blood; D011379:Prognosis
D018394:CA-125 Antigen