title: [Glycyrrhizinic Acid Reference Standard (Control 001) of National Institute of Health Sciences].
abstract: The raw material of glycyrrhizinic acid was examined for preparation of the "Glycyrrhizinic Acid Reference Standard". The analytical data obtained were: UV spectrum: lambda max, 251 nm; and specific absorbance (E1ca1%) in ethanol at 251 nm, 146; IR spectrum, specific absorptions at 1714, 1655, 1215, and 1170 cm-1; and the spectrum of raw material was consistent with that of Standard (Control 991). Also, thin-layer chromatography, no impurity was detected; high-performance liquid chromatography, several impurities were detected. The amount of each impurity was estimated at less than 0.2% and total amount of impurities was less than 0.4%. Based on the above results, the candidate material was authorized as the Glycyrrhizinic Acid Reference Standard (Control 001) of the National Institute of Health Sciences.
authors.forename: T
authors.initials: T
authors.lastname: Koide
authors.forename: M
authors.initials: M
authors.lastname: Iwata
authors.forename: K
authors.initials: K
authors.lastname: Maekawa
authors.forename: H
authors.initials: H
authors.lastname: Saito
authors.forename: T
authors.initials: T
authors.lastname: Tanimoto
authors.forename: S
authors.initials: S
authors.lastname: Okada
mesh_terms: D002851:Chromatography, High Pressure Liquid; D019695:Glycyrrhizic Acid / Q000032:analysis / Q000592:standards*; D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards; D012015:Reference Standards
chemical_list: D019695:Glycyrrhizic Acid