Concomitant focal fibrocartilaginous dysplasia of the tibia and eosinophilic granuloma of the jaw in a child.
This 2-year-old child presented with concomitant eosinophilic granuloma of the lower jaw and focal fibrocartilaginous dysplasia of the right tibia. Her eosinophilic granuloma was diagnosed on the basis of the clinical picture, imaging studies and the characteristic histologic appearance. Focal fibrocartilaginous dysplasia was revealed incidentally during the eosinophilic granuloma staging process. After chemotherapy, all signs of eosinophilic granuloma subsided, but focal fibrocartilaginous dysplasia remained without signs of clinical or radiographic progression. The importance of differentiating these two conditions is stressed in order to avoid ineffective and inappropriate treatment of focal fibrocartilaginous dysplasia.
Postovsky
Sergey
S
Department of Pediatric Hematology Oncology, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Militianu
Daniela
D
Bialik
Victor
V
Vlodavsky
Eugene
E
Elhasid
Ronit
R
Peled
Micha
M
Arush
Myriam Weyl Ben
MW
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D001707:Biopsy, Needle; D002675:Child, Preschool; D004803:Eosinophilic Granuloma / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007573:Jaw Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology; D016896:Treatment Outcome