title: Dual X-ray absorptiometry of hip, heel ultrasound, and densitometry of fingers can discriminate male patients with hip fracture from control subjects: a comparison of four different methods.
abstract: Few studies have examined different bone densitometry techniques to determine male hip fracture risk. We conducted a case-control study of 31 noninstitutionalized men, mean age 77 yr, with a first hip fracture and compared the results with 68 randomly selected age-matched control subjects. The methods used were dual X-ray absorptiometry (DXA) of the proximal femur, quantitative ultrasound (QUS) of the heel and fingers, and radiographic absorptiometry of the fingers. Case patients had significantly lower values (4-17%; p < 0.01) for all methods. The odds ratios for every SD reduction in bone values were 4.8 (95% confidence interval [CI]: 2.3-9.9) for DXA of the femoral neck, 2.2 (95% CI: 1.2-3.9) for QUS of the heel, 2.0 (95% CI: 1.2-3.3) for QUS of the phalanges, and 3.1 (95% CI: 1.5-6.6) for radiographic absorptiometry of the phalanges. The results indicate a strong capability of DXA of the femoral neck to distinguish between men with a first hip fracture and control subjects. Furthermore, ultrasound of the heel and fingers as well as radiographic absorptiometry proved capable of discriminating men with hip fractures from control subjects.
authors.affiliation: Department of Surgery, Orthopedic Unit, University Hospital, Uppsala, Sweden. Anna.Ekman@ortopedi.uu.se
authors.forename: Anna
authors.initials: A
authors.lastname: Ekman
authors.forename: Karl
authors.initials: K
authors.lastname: Michaëlsson
authors.forename: Marianne
authors.initials: M
authors.lastname: Petrén-Mallmin
authors.forename: Sverker
authors.initials: S
authors.lastname: Ljunghall
authors.forename: Hans
authors.initials: H
authors.lastname: Mallmin
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D002111:Calcaneus / Q000000981:diagnostic imaging*; D016022:Case-Control Studies; D005269:Femur / Q000000981:diagnostic imaging* / Q000502:physiology; D005385:Fingers / Q000000981:diagnostic imaging*; D006620:Hip Fractures / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D008297:Male; D012372:ROC Curve; D012680:Sensitivity and Specificity; D014463:Ultrasonography