[Significance of 99mTc-labeled perfusion agents in the simultaneous assessment of myocardial perfusion and cardiac function].
Simultaneous assessment of left ventricular myocardial perfusion and systolic function was accomplished by utilizing ECG-gated myocardial perfusion SPECT. This development in nuclear cardiology will be attributed to the recent advances in new 99mTc-labeled perfusion agents, multi-detector SPECT system and software for automatic edge-detection of the left ventricle. In this article, we described about the clinical utilities of this method in detecting "hibernating myocardium," severe coronary artery disease patients with exercise-induced LV dysfunction, in predicting functional recovery after reperfusion therapy for acute myocardial infarction patients and in diagnosing patients with right heart diseases.
Ishida
Yoshio
Y
D003326:Coronary Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004562:Electrocardiography; D015637:Gated Blood-Pool Imaging; D006801:Humans; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D012720:Severity of Illness Index; D012984:Software; D013599:Systole; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D016277:Ventricular Function, Left
D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin; D017256:Technetium Tc 99m Sestamibi