Drug-induced lupus erythematosus by amiodarone.
We report a case with typical clinical features of drug-induced lupus erythematosus, together with verrucous endocarditis and pleuropericardial effusion, due to amiodarone treatment. After cessation of amiodarone treatment, the patient recovered completely.
Sheikhzadeh
Abdalhamid
A
Segeberger Heart Centre, Am Kurpark 1, D-23795 Bad-Segeberg, Germany. urschaefer@hotmail.com
Schäfer
Ulrich
U
Schnabel
Armin
A
D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis; D004696:Endocarditis / Q000139:chemically induced; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000139:chemically induced; D010996:Pleural Effusion / Q000139:chemically induced; D011239:Prednisolone / Q000627:therapeutic use
D000889:Anti-Arrhythmia Agents; D000893:Anti-Inflammatory Agents; D000974:Antibodies, Antinuclear; D005340:Fibrinogen; D002097:C-Reactive Protein; D011239:Prednisolone; D000638:Amiodarone