title: The significance of anti-Müllerian hormone concentration in seminal plasma for spermatogenesis.
abstract: BACKGROUND
  The function of anti-Müllerian hormone (AMH) in seminal plasma in adulthood is uncertain. We examined the significance of seminal AMH for spermatogenesis.
  
  
  METHODS
  We measured seminal concentrations of AMH in 39 oligozoospermic men (mean age +/- SD, 32.7 +/- 4.3 years) and 10 normal volunteers to examine the association of seminal AMH with spermatogenesis. The seminal concentrations of AMH in oligozoospermic men (149.3 +/- 254.0 pmol/l) were significantly lower than in normal men (249.0 +/- 167.7 pmol/l; P +/- 0.0337). Seminal AMH concentration correlated significantly with sperm concentration (r = 0.339, P = 0.0350) and mean testicular volume (r = 0.440, P = 0.246). The serum concentration of LH (r = - 0.365, P = 0.0241), but not FSH, testosterone or estradiol, correlated significantly with AMH concentration in seminal plasma.
  
  
  CONCLUSIONS
  AMH in seminal plasma may be important for sperm production, and is a good marker for Sertoli cell development.
authors.affiliation: Division of Urology, Department of Organ Therapeutics, Kobe University Graduate School of Medicine, Kobe, Japan. masato@med.kobe-u.ac.jp
authors.forename: Masato
authors.initials: M
authors.lastname: Fujisawa
authors.forename: Takafumi
authors.initials: T
authors.lastname: Yamasaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okada
authors.forename: Sadao
authors.initials: S
authors.lastname: Kamidono
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone; D006023:Glycoproteins; D006131:Growth Inhibitors / Q000378:metabolism*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009845:Oligospermia / Q000378:metabolism* / Q000473:pathology; D009929:Organ Size; D009994:Osmolar Concentration; D012016:Reference Values; D012661:Semen / Q000166:cytology / Q000378:metabolism*; D013076:Sperm Count; D013091:Spermatogenesis / Q000502:physiology*; D013735:Testicular Hormones / Q000378:metabolism*; D013737:Testis / Q000473:pathology
chemical_list: D006023:Glycoproteins; D006131:Growth Inhibitors; D013735:Testicular Hormones; D054304:Anti-Mullerian Hormone; D007986:Luteinizing Hormone