title: [Current aspects of hepatotoxicity in occupational medicine].
abstract: A large number of chemical agents encountered occupationally are known as potential hepatotoxins. The practical relevance of these results should be considered critically for the individual case and under usual work layout. In this paper the current state of knowledge for hepatotoxicity in occupational medicine is described. Different diagnostical methods and criteria for suspected chemical-induced liver injury are shown. The paper focuses on the potential hepatotoxic effects of chronic exposures to solvents, since these substances are used in a large variety of modern places of work. On the basis of field studies in occupationally exposed workers the potential hepatotoxical effects of mixtures of solvents are discussed. Recommendations for medical surveillance places of work are proposed.
authors.affiliation: Institut und Poliklinik für Arbeits- und Sozialmedizin der Universität Heidelberg, Germany. Joerg_Hoffmann@med.uni-heidelberg.de
authors.forename: J
authors.initials: J
authors.lastname: Hoffmann
authors.forename: G
authors.initials: G
authors.lastname: Triebig
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008111:Liver Function Tests; D008403:Mass Screening; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012997:Solvents / Q000009:adverse effects*
chemical_list: D000395:Air Pollutants, Occupational; D012997:Solvents
vernacular_title: Aktuelle arbeitsmedizinische Aspekte zur Hepatotoxizität von Arbeitsstoffen.