title: Virulence factors of Escherichia cofi from cellulitis or colisepticemia lesions in chickens.
abstract: This study was designed to compare virulence factors of cellulitis-derived Escherichia coli to colisepticemic E. coli in order to clarify whether E. coli associated with cellulitis comprise a unique subset of pathogenic E. coli. Isolates were tested for serotype, capsule, aerobactin production, colicin production, the presence of the iss gene, and serum resistance. Untypable isolates made up the greatest percentage of each group. Serotypes O2 and O78 were the most commonly identified among both groups of isolates. No statistical differences in the distribution of aerobactin or colicin production, capsule, or iss gene were observed between groups. Cluster analysis showed that 90% of the E. coli isolates had greater than 42% livability in serum-resistance tests. No separation of colisepticemic vs. cellulitis E. coli isolates was observed on the basis of SR. Colicin production by E. coli was highly correlated with serum resistance (P = 0.0029). These data suggest that cellulitis E. coli have virulence traits similar to those of colisepticemic E. coli.
authors.affiliation: Department of Population, Health and Reproduction, School of Veterinary Medicine, Veterinary Medicine Teaching and Research Center, Tulare, CA 93274, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Jeffrey
authors.forename: L K
authors.initials: LK
authors.lastname: Nolan
authors.forename: K H
authors.initials: KH
authors.lastname: Tonooka
authors.forename: S
authors.initials: S
authors.lastname: Wolfe
authors.forename: C W
authors.initials: CW
authors.lastname: Giddings
authors.forename: S M
authors.initials: SM
authors.lastname: Horne
authors.forename: S L
authors.initials: SL
authors.lastname: Foley
authors.forename: A M
authors.initials: AM
authors.lastname: Lynne
authors.forename: J O
authors.initials: JO
authors.lastname: Ebert
authors.forename: L M
authors.initials: LM
authors.lastname: Elijah
authors.forename: G
authors.initials: G
authors.lastname: Bjorklund
authors.forename: S J
authors.initials: SJ
authors.lastname: Pfaff-McDonough
authors.forename: R S
authors.initials: RS
authors.lastname: Singer
authors.forename: C
authors.initials: C
authors.lastname: Doetkott
mesh_terms: D000818:Animals; D016470:Bacteremia / Q000382:microbiology / Q000662:veterinary*; D015373:Bacterial Typing Techniques / Q000662:veterinary; D002481:Cellulitis / Q000382:microbiology / Q000662:veterinary*; D002645:Chickens; D016000:Cluster Analysis; D003087:Colicins / Q000096:biosynthesis; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000145:classification / Q000302:isolation & purification / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D006877:Hydroxamic Acids; D011201:Poultry Diseases / Q000382:microbiology*; D014774:Virulence
chemical_list: D003087:Colicins; D006877:Hydroxamic Acids; C031819:aerobactin