Antimicrobial use prior to the acquisition of multiresistant bacteria.
We assessed whether patients who acquired methicillin-resistant Staphylococcus aureus (MRSA) had less exposure to antimicrobial agents than did those who acquired Enterobacteriaceae that produced extended-spectrum beta-lactamase (ESbetaL). In a 6-month, prospective study, ESbetaL carriers had received antimicrobial therapy more often than had MRSA carriers. Amoxicillin-clavulanic acid, fluoroquinolones, and third-generation cephalosporins, especially ceftazidime, had been prescribed more often for ESbetaL carriers than for MRSA carriers.
Eveillard
Matthieu
M
Department of Bacteriology, Hygiene and Infection Control, Hôpital Nord, Amiens, France.
Schmit
Jean-Luc
JL
Eb
François
F
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002353:Carrier State; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D017723:Drug Utilization Review; D004756:Enterobacteriaceae Infections / Q000188:drug therapy* / Q000382:microbiology; D005602:France; D006785:Hospitals, University; D006801:Humans; D016106:Methicillin Resistance; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification
D000900:Anti-Bacterial Agents