Heparin-induced priapism.
Heparin-induced priapism constitutes a special form of pharmaco-induced prolonged erection, but the pathophysiological principles are not yet definitely clear. Heparin-induced antiplatelet-antibodies may lead to the aggregation of thrombocytes and thus alter the penile blood flow leading to low-flow priapism. Alternatively, this condition may be explained by initial high-flow priapism that later turns into ischemic priapism. The question remains whether hemorrhage with subsequent organisation of the hematoma and late fibrosis constitutes a pathogenetic factor. Besides this pathogenetic discussion, this paper presents the differential diagnosis of priapism as well as diagnostic and therapeutic procedures.
Bschleipfer
T H
TH
Department of Urology, Bundeswehrkrankenhaus Ulm, Germany.
Hauck
E W
EW
Diemer
T H
TH
Bitzer
M
M
Kirkpatrick Ch
J
J
Pust
R A
RA
Weidner
W
W
D000328:Adult; D003937:Diagnosis, Differential; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011317:Priapism / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis
D006493:Heparin