Disintegration or altering of intact mitochondria or digitonin inner membrane + matrix particles causes an increase in K(+)-linked release of protons. This effect is not obtainable in the case of outer membranes. It is assumed, that also the inner membrane + matrix possesses exchange sites for K(+), which are freely accessible for the potassium ion if the structural integrity is damaged. The outer layer of inner membrane seems to be a barrier for the K(+)-movement.
Lutze
G
G
Physiol.-chem. Institut der Medizinischen Akademie Madgeburg, DDR
Liese
W
W
Kunz
W
W
Uber die beziehungen zwischen einem energieunabhängigen K(+)-H(+)-austausch und der strukturellen integrität von mitochondrien und membranpartikeln.