title: Medical informatics: searching for underlying components.
abstract: OBJECTIVE
  To discuss unifying principles that can provide a theory for the diverse aspects of work in medical informatics. If medical informatics is to have academic credibility, it must articulate a clear theory that is distinct from that of computer science or of other related areas of study.
  
  
  RESULTS
  The notions of reusable domain antologies and problem-solving methods provide the foundation for current work on second-generation knowledge-based systems. These abstractions are also attractive for defining the core contributions of basic research in informatics. We can understand many central activities within informatics in terms defining, refining, applying, and evaluating domain ontologies and problem-solving methods.
  
  
  CONCLUSIONS
  Construing work in medical informatics in terms of actions involving ontologies and problem-solving methods may move us closer to a theoretical basis for our field.
authors.affiliation: Stanford University School of Medicine, Stanford, California, USA. musen@Stanford.EDU
authors.forename: M A
authors.initials: MA
authors.lastname: Musen
mesh_terms: D007254:Information Science; D008490:Medical Informatics / Q000193:education / Q000379:methods / Q000639:trends; D008491:Medical Informatics Applications