title: [Dust exposure and cancer risk associated with amphibolite mining and processing].
abstract: Mining and processing of amphibolite is associated with workers' exposure to dust containing asbestos minerals (actinolite, tremolite) and with the presence of respirable fibers, i.e. small particles above 5 microns long and below 3 microns in diameter (with length-to-diameter ratio higher than 3:1). Results of epidemiological and laboratory studies show that such dust may be responsible for the development of cancer in dust-exposed people. This work reports the measurement results of concentrations of total dust, respirable fibers and mineral composition of samples collected in plant mining and processing amphibolite rock. Based on the results, cumulated exposure was calculated for the 10-, 20- and 30-year exposure periods. The cumulated exposure was classified into two categories: 0.1-1.0 f/cm3 years and 1.0-10 f/cm3. x years. It has been found that mining and processing of amphibolite is associated with increased risk of death from mesothelioma--11.2 x 10(-5) (crushers--10 years of exposure) to 240.0 x 10(-5) (miners--30 years of exposure). The risk of excessive mortality from lung cancer was not high (below 1. x 10(-4)) for all workplaces and periods of exposure.
authors.affiliation: Zakładu Zagrozeń Chemicznych i Pyłowych Pracownia Aerozoli i Mikroklimatu Instytutu Medycyny Pracy im. prof. J. Nofera w Łodzi.
authors.forename: H
authors.initials: H
authors.lastname: Woźniak
authors.forename: E
authors.initials: E
authors.lastname: Wiecek
authors.forename: G
authors.initials: G
authors.lastname: Bielichowska-Cybula
authors.forename: B
authors.initials: B
authors.lastname: Opalska
mesh_terms: D000328:Adult; D017636:Asbestos, Amphibole / Q000009:adverse effects* / Q000032:analysis; D002273:Carcinogens / Q000009:adverse effects* / Q000032:analysis; D004391:Dust / Q000009:adverse effects* / Q000032:analysis; D004784:Environmental Monitoring; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced; D008452:Maximum Allowable Concentration; D008654:Mesothelioma / Q000139:chemically induced; D008906:Mining; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis; D011044:Poland; D018570:Risk Assessment; D013997:Time Factors
chemical_list: D017636:Asbestos, Amphibole; D002273:Carcinogens; D004391:Dust; C036431:ferroactinolite; C005846:tremolite
vernacular_title: Narazenie na pył oraz ryzyko nowotworowe zwiazane z wydobyciem i przerobem amfibolitu.