Modified radical vaginal hysterectomy with or without laparoscopic nerve-sparing dissection: a comparative study.
OBJECTIVE
Nerve-sparing dissection of the lateral portion of the cardinal ligament (paracervical lymphadenectomy) has been recently developed with the goal of reducing the late urinary adverse effects of radical hysterectomy without impairing the outcome. This work has been carried out in order to investigate the influence of additional paracervical lymph node dissection at the time of laparoscopically assisted modified radical hysterectomy on outcome and urinary sequelae.


METHODS
A total of 95 patients underwent a modified radical hysterectomy using a combined laparoscopic and vaginal approach since 1991. In 47 of these patients treated since 1996 an additional laparoscopic paracervical lymphadenectomy was performed. The operative, postoperative, and survival outcomes were assessed. In 60 patients, 32 and 28 in the groups of patients with or without paracervical dissection, respectively, a careful interview on urinary symptoms was conducted by an independent investigator.


RESULTS
Paracervical dissection involves no operative complication and lenghthens the postoperative urinary retention, but has no adverse influence on long-term urinary discomfort. The yield of paracervical dissection is negligible for small tumors: no positive node was found in 38 patients with tumors less than 2 cm in diameter. The outcome of patients after minimal access surgery for tumors less than 2 cm is excellent whether or not a paracervical dissection has been performed.


CONCLUSIONS
Paracervical dissection does not worsen the late urinary symptoms after vaginal radical hysterectomy. It has a limited value in the surgical management of small-size (less than 2 cm) cervical cancers, although it may prevent long-term lateropelvic recurrences.
Querleu
Denis
D
Department of Gynecologic Oncology, University of Lille II, Centre Oscar Lambret, 2 avenue Frédéric Combemale, Lille, 59020, France. d-querleu@o-lambret.fr
Narducci
Fabrice
F
Poulard
Valery
V
Lacaze
Sophie
S
Occelli
Bruno
B
Leblanc
Eric
E
Cosson
Michel
M
D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects / Q000379:methods*; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods; D008022:Ligaments / Q000294:innervation / Q000601:surgery; D008197:Lymph Node Excision / Q000379:methods; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000209:etiology; D016055:Urinary Retention / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000601:surgery*