[Diagnostic significance of sleep EEG in children with febrile seizures].
To obtain effective criteria for febrile seizures (FS) differential diagnosis and prognosis, clinical examination and EEG recorded during wakefulness and daytime sleep were studied in 75 FS children and 15 controls aged from 6 months to 6 years. According to duration, frequency and complications of FS, all patients were divided into three groups: "simple" FS (n = 35), "complex" FS (n = 25) and "afebrile seizures" (AFS), i.e. those who developed non-febrile seizures after febrile ones (n = 15). In waking state EEG, epileptic activity was found in only 60% of AFS patients. During sleep stages I-III, in 84% of the patients with complex FS as well as in all AFS patients generalized discharges of (poly) spike-waves and (or) focal spikes were detected. Paroxysmal changes, atypical scalp distribution, vertex-potentials and sleep spindles generalization as well as insertion of spikes into arousal-rhythms were determined as additional criteria for unfavorable FS course. In the patients with main features of sympathetic-adrenal reaction during febrile paroxysms, complicated FS course was not found. EEG examination during sleep in children with FS increases an efficacy of differential disease diagnosis. Epileptic discharge detection, along with exposure of paroxysmal transformation of physiological sleep EEG transients, that may be earlier sign of epileptic dysfunction, are recommended for proper prevention and treatment of FS.
Kovelenova
M V
MV
Rozhkov
V P
VP
Guzeva
V I
VI
D001143:Arousal / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D003294:Seizures, Febrile / Q000175:diagnosis*; D012895:Sleep, REM / Q000502:physiology*
Diagnostichekoe znachenie EEG sna u deteĭ s febril'nymi sudorogami.