title: ECT for the treatment of psychiatric symptoms in Basedow's disease.
abstract: To treat psychiatric symptoms associated with hyperthyroidism, we administered electroconvulsive therapy (ECT) to a patient with Basedow's disease. After unsuccessful treatment with an oral antithyroid drug, neuroleptics, and mood stabilizer, the patient recovered completely after three ECTs and did not relapse in the 40-day follow-up period. Although hyperthyroidism has been considered to induce psychiatric symptoms by enhancement of the sensitivity and turnover in catecholaminergic neurotransmission, we suggest another possible mechanism, involving translational and activational regulation of functional proteins in the brain.
authors.affiliation: Department of Psychiatry, Jichi Medical School, Minamikawachi, Tochigi. nibrin@jichi.ac.jp
authors.forename: Masashi
authors.initials: M
authors.lastname: Nibuya
authors.forename: Hisashi
authors.initials: H
authors.lastname: Sugiyama
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Shioda
authors.forename: Kenshi
authors.initials: K
authors.lastname: Nakamura
authors.forename: Koichi
authors.initials: K
authors.lastname: Nishijima
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000209:etiology / Q000628:therapy*; D003221:Confusion / Q000209:etiology / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000523:psychology*; D006801:Humans; D010554:Personality Disorders / Q000209:etiology / Q000628:therapy; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents