Reversible brain injury in a head-injured patient identified by magnetic resonance imaging and spectroscopy.
Serial MRI studies of a severely head-injured patient showed extensive diffusion abnormalities lasting for 40 days. These were related to initial perfusion abnormalities and improved in parallel with clinical status. Spectroscopy showed diffuse damage and pH changes. Together these data support a role for ischaemia in head injury.
Blamire
A M
AM
MRC Biochemical and Clinical Magnetic Resonance Spectroscopy Unit, John Radcliffe Hospital, Oxford, UK.
Cadoux-Hudson
T
T
Rajagopalan
B
B
D000293:Adolescent; D001642:Bicycling / Q000293:injuries*; D001930:Brain Injuries / Q000175:diagnosis* / Q000503:physiopathology; D004058:Diffusion; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male