Drug use in renal failure.
A number of medications used in the presence of renal disease require dose adjustments be made. The health care professional should know a drug's route of elimination, the percentage of protein binding, and the percentage of a normal dose removed by dialysis. This information is a guideline and should be used to start therapy. The clinician must understand that individual adjustments are the rule rather than the exception.
Haney
Sharon L
SL
Department of Surgery, Transplant Services, Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina 27157, USA. shaney@wfubmc.edu
D058186:Acute Kidney Injury / Q000188:drug therapy / Q000378:metabolism / Q000451:nursing; D004358:Drug Therapy; D006207:Half-Life; D006801:Humans; D007408:Intestinal Absorption; D007668:Kidney / Q000502:physiology*; D010599:Pharmacokinetics; D014018:Tissue Distribution