title: Chemical composition and biological activity of the volatiles of Anthemis melampodina and Pluchea dioscoridis.
abstract: The volatile fractions obtained by hydrodistillation of the fresh leaves of Anthemis melampodina and Pluchea dioscoridis were analysed by GC-MS technique. Of 38 components identified in the volatile oil of A. melampodina, santolinatriene was the major component (27.33%). The oil was characterized by a high percentage of monoterpene hydrocarbons (49.94%) while sesquiterpene hydrocarbons and oxygenated sesquiterpenes represented only 7.41% and 11.43% of the oil. 36 components were identified in the volatile oil of P. dioscoridis. Farnesol was the major component (16.50%) accompanied by a high percentage of sesquiterpene alcohols. Oxygenated sesquiterpenes (26.43%) and sesquiterpene hydrocarbons (39.43%) represented the main constituents in the oil. P. dioscoridis showed a marked mosquito larvicidal activity against Culex pipiens (LC(50) 71.86 ppm), while A. melampodina was moderately active (LC(50) 139.42 ppm).
authors.affiliation: Chemistry of Natural and Microbial Products Department, National Research Centre, Dokki, Cairo, Egypt. mhgrace@thewayout.net
authors.forename: Mary H
authors.initials: MH
authors.lastname: Grace
mesh_terms: D000818:Animals; D019659:Asteraceae; D001681:Biological Assay; D009033:Culicidae / Q000187:drug effects*; D008401:Gas Chromatography-Mass Spectrometry; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry / Q000378:metabolism; D011722:Pyrethrins / Q000494:pharmacology; D012717:Sesquiterpenes / Q000032:analysis
chemical_list: D009822:Oils, Volatile; D011722:Pyrethrins; D012717:Sesquiterpenes; C051001:cyphenothrin