Cutaneous malignant fibrous histiocytoma with the characteristics of different variants.
We report the case of a 50-year-old woman with cutaneous malignant fibrous histiocytoma (MFH) on the right hypogastric region. A purplish-red blood-filled tumor, approximately 40 mm in diameter, was detected on the region. A histopathologic analysis of the excised tumor showed that it extended from the upper dermis to the subcutaneous tissue over the fascia and, furthermore, that a variety of cells, from highly atypical spindle shaped to histiocytelike, were embedded in the collagenous stroma without forming a capsule. The storiform pattern was not significant. In addition, an area occupied primarily by multinucleated giant cells and rich in vascular components was observed in the deep portion of the tumor that came into contact with the bloody contents. Based on these findings, the patient was diagnosed as having a cutaneous MFH exhibiting the characteristics of different variants.
Kakizoe
Eiichi
E
Kakizoe Clinic of Dermatology, Kurume, Japan.
Kakizoe
Fukuko
F
Kakizoe
Kenji
K
Okunishi
Hideki
H
D000005:Abdomen; D001706:Biopsy; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery