title: Early thrombolysis in stroke due to basilar artery occlusion.
abstract: Basilar artery occlusion is usually associated with a poor prognosis. Nevertheless, intra-arterial thrombolysis has been shown to improve clinical outcome in selected cases. We report the case of a 29-year-old patient who suffered a severe ischemic stroke due to basilar artery occlusion and who was treated with intra-arterial thrombolysis within 3 h of symptoms onset; treatment was followed by an almost full functional recovery. The young age of the patient, short segment occlusion in the middle tract of the artery, good collateral supply, and early recanalization may account for the favorable prognosis.
authors.affiliation: Department of Neuroscience, Neurologic Clinic, University of Pisa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Orlandi
authors.forename: G
authors.initials: G
authors.lastname: Moscato
authors.forename: R
authors.initials: R
authors.lastname: Padolecchia
authors.forename: F
authors.initials: F
authors.lastname: Sartucci
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000494:pharmacology; D001488:Basilar Artery / Q000000981:diagnostic imaging / Q000473:pathology; D001933:Brain Stem / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D020526:Brain Stem Infarctions / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D004334:Drug Administration Schedule; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020127:Recovery of Function / Q000187:drug effects; D015912:Thrombolytic Therapy / Q000379:methods*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D017585:Ultrasonography, Doppler, Transcranial; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D014859:Warfarin / Q000494:pharmacology
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D014859:Warfarin; D006493:Heparin; D014568:Urokinase-Type Plasminogen Activator