title: Chromatin assembly: the kinetochore connection.
abstract: An unexpected new role for the chromatin assembly factor CAF-1 and the histone-regulating Hir proteins has been discovered in budding yeast. Both protein complexes are required together for building functional kinetochores.
authors.affiliation: University of Cambridge, Department of Zoology, Downing Street, CB2 3EJ, Cambridge, UK. tk1@mole.bio.cam.ac.uk
authors.forename: Torsten
authors.initials: T
authors.lastname: Krude
mesh_terms: D002135:Calcium-Binding Proteins / Q000235:genetics / Q000378:metabolism; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D002503:Centromere / Q000378:metabolism; D002843:Chromatin / Q000378:metabolism / Q000502:physiology*; D056504:Chromatin Assembly Factor-1; D002868:Chromosomal Proteins, Non-Histone; D020090:Chromosome Segregation / Q000502:physiology*; D004261:DNA Replication; D004271:DNA, Fungal / Q000096:biosynthesis; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D018386:Kinetochores / Q000378:metabolism / Q000502:physiology*; D064246:Mad2 Proteins; D016296:Mutagenesis; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D012097:Repressor Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins
chemical_list: C533593:CHAF1B protein, human; C092746:CSE4 protein, S cerevisiae; D002135:Calcium-Binding Proteins; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D002843:Chromatin; D056504:Chromatin Assembly Factor-1; D002868:Chromosomal Proteins, Non-Histone; D004271:DNA, Fungal; D004268:DNA-Binding Proteins; D005656:Fungal Proteins; C078808:HIR1 protein, S cerevisiae; C577695:MAD2 protein, S cerevisiae; D064246:Mad2 Proteins; D009687:Nuclear Proteins; D012097:Repressor Proteins; D029701:Saccharomyces cerevisiae Proteins