[Hallucinations caused by paroxetine taken together with a levodopa-carbidopa preparation].
A 79-year-old woman suffering from Parkinson's disease, for which she was taking a levodopa-carbidopa preparation, was prescribed the selective serotonin reuptake inhibitor paroxetine 20 mg once daily. After taking the first tablet she started to suffer from visual hallucinations. Once she stopped taking the paroxetine, the hallucinations ceased immediately. A link between the paroxetine and the hallucinations seemed likely, with a possible interaction between the paroxetine and the levodopa-carbidopa combination.
Freijzer
P L
PL
Huisartsenpraktijk Richtershagen, C. Looierstraat 3-04, 7131 DJ Lichtenvoorde.
Brenninkmeijer
J H E
JH
D000368:Aged; D000978:Antiparkinson Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002230:Carbidopa / Q000008:administration & dosage / Q000627:therapeutic use; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D006212:Hallucinations / Q000139:chemically induced*; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage / Q000627:therapeutic use; D010300:Parkinson Disease / Q000188:drug therapy*; D017374:Paroxetine / Q000009:adverse effects* / Q000627:therapeutic use; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use
D000978:Antiparkinson Agents; D002230:Carbidopa; D007980:Levodopa; D017374:Paroxetine; D017367:Selective Serotonin Reuptake Inhibitors
Hallucinaties veroorzaakt door paroxetine bij gebruik van de combinatie levodopa-carbidopa.