title: Replacement of the intervening amino acid sequence of a Syk-binding diphosphopeptide by a nonpeptide spacer with preservation of high affinity.
authors.affiliation: Department of Medicinal Chemistry, Utrecht Institute of Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Dekker
authors.forename: Nico J
authors.initials: NJ
authors.lastname: de Mol
authors.forename: Jeroen
authors.initials: J
authors.lastname: van Ameijde
authors.forename: Marcel J E
authors.initials: MJ
authors.lastname: Fischer
authors.forename: Rob
authors.initials: R
authors.lastname: Ruijtenbeek
authors.forename: Frank A M
authors.initials: FA
authors.lastname: Redegeld
authors.forename: Rob M J
authors.initials: RM
authors.lastname: Liskamp
mesh_terms: D000595:Amino Acid Sequence; D004792:Enzyme Precursors / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D047908:Intracellular Signaling Peptides and Proteins; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010748:Phosphopeptides / Q000138:chemical synthesis* / Q000378:metabolism / Q000502:physiology; D011505:Protein-Tyrosine Kinases / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D020349:Surface Plasmon Resonance; D000072377:Syk Kinase
chemical_list: D004792:Enzyme Precursors; D047908:Intracellular Signaling Peptides and Proteins; D010748:Phosphopeptides; D011994:Recombinant Proteins; D011505:Protein-Tyrosine Kinases; D000072377:Syk Kinase