Anti-GBM nephritis complicating diabetic nephropathy.
There are several reports of glomerulonephritis (GN) in diabetics or patients with diabetic glomerulosclerosis. Cases of rapidly progressive GN where crescentic histologic changes are superimposed on diabetic glomerulosclerosis are very unusual. We report the case of a patient with type I diabetes mellitus, who developed rapidly progressive renal insufficiency. Renal biopsy disclosed anti-glomerular basement membrane nephritis superimposed on classical diabetic glomerulosclerosis.
Curioni
Simona
S
Renal Immunopathology Center, San Carlo Borromeo Hospital, Milan, Italy.
Ferrario
Franco
F
Rastaldi
Maria P
MP
Colleoni
Natale
N
Colasanti
Giuliano
G
D'Amico
Giuseppe
G
D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications* / Q000276:immunology / Q000473:pathology; D003928:Diabetic Nephropathies / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008297:Male; D006435:Renal Dialysis