title: [Allergic reactions to local anesthetics].
abstract: In this article type I and type IV allergic reactions evoked by local anaesthetics are discussed. Contact dermatitis (type IV) reactions are mainly caused by local anaesthetics of the ester-type like procaine. Both contact dermatitis and anaphylactic reactions (type I) can be caused by anaesthetics of the amide-type (e.g. lidocaine), but these reactions are rare. Intra- and epicutaneous tests can be useful to prove allergy, but sometimes provocation tests are necessary. Many reactions are not caused by an allergic mechanism.
authors.affiliation: Afdeling Arbeidsdermatologie/Dermato allergologie, Academisch Ziekenhuis Vrije Universiteit te Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam.
authors.forename: D P
authors.initials: DP
authors.lastname: Bruynzeel
mesh_terms: D000707:Anaphylaxis / Q000209:etiology / Q000276:immunology; D000766:Anesthesia, Dental / Q000009:adverse effects; D000779:Anesthetics, Local / Q000009:adverse effects* / Q000276:immunology; D017449:Dermatitis, Allergic Contact / Q000209:etiology; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000276:immunology; D006801:Humans; D006968:Hypersensitivity, Delayed; D006969:Hypersensitivity, Immediate
chemical_list: D000779:Anesthetics, Local
vernacular_title: Allergische reacties op lokale anaesthetica.