A hypothesis of the stomatocytosis in individuals with the phenotype Rh(null).
A hypothesis of the stomatocytosis in individuals with the Rh(null) phenotype is proposed on the assumptions that the RhAG polypeptide of the Rh antigenic complex has the function of transporting ammonium and that a previously proposed mechanism of erythrocyte shape control is valid.
Wong
P
P
Department of Oncology, McGill University, Montreal, Quebec, Canada. pwong@med.mcgill.ca
D000641:Ammonia / Q000097:blood; D000743:Anemia, Hemolytic / Q000097:blood; D048429:Cell Size; D004913:Erythrocytes, Abnormal / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008954:Models, Biological; D010641:Phenotype; D012204:Rh-Hr Blood-Group System / Q000097:blood*
D012204:Rh-Hr Blood-Group System; D000641:Ammonia