[Use of local magnitothermia in the treatment of patients with primary-confined skin melanoma].
We studied modifying potentialities of high temperatures in treatment regimens with adjuvant endolymphatic chemo- and interferontherapy of malignant melanoma of the skin. We had previously obtained enough evidence for expediency of adjuvant endolymphatic therapy of primary-localized melanoblastoma of the skin. Added to the preventive treatment regimens were sessions of local magnetothermia. The study was done in patients diagnosed as having primary-localized melanoma of the skin T(2-4) No Mo. A 3-year recurrence-free survival in the control group was (38.2 +/- 1.6)%, in the first study group--(54.2 +/- 5.8)%, in the second study group--(44.3 +/- 13.5)%. The general 3-year survival in the control group was (67.7 +/- 1.5)%, in the first study group--(70.8 +/- 5.5)%, in the second one--(91.7 +/- 5.7)%. In this way, the expediency has been proved of employment of local magnetothermia in treatment regimens to deal with malignant melanoma of the skin.
Korovin
S I
SI
Tolstopiatov
B A
BA
Medinets
Iu R
IuR
Protsenko
V V
VV
Dedkov
A G
AG
Palivets
A Iu
AIu
Smakova
M S
MS
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003606:Dacarbazine / Q000627:therapeutic use; D004574:Electromagnetic Fields; D005260:Female; D006358:Hot Temperature / Q000627:therapeutic use*; D006801:Humans; D007267:Injections; D007370:Interferon Type I / Q000627:therapeutic use; D016898:Interferon-alpha; D008208:Lymphatic System; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000628:therapy*; D008875:Middle Aged; D011994:Recombinant Proteins; D012878:Skin Neoplasms / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate
D000276:Adjuvants, Immunologic; D018906:Antineoplastic Agents, Alkylating; D007370:Interferon Type I; D016898:Interferon-alpha; D011994:Recombinant Proteins; C076799:interferon-alpha 8; D003606:Dacarbazine
Opyt primeneniia lokal'noĭ magnitotermii pri lechenii bol'nykh s pervichno-ogranichennoĭ melanomoĭ kozhi.