The message and the messenger: delivering RNA in neurons.
Synaptic plasticity results in enduring changes in synaptic function. Localized protein synthesis is part of this process. Kosik and Krichevsky describe how a dynamic macromolecular structure, the RNA granule, may be a key element contributing to changes in protein production leading to synaptic plasticity.
Kosik
Kenneth S
KS
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. kosik@rics.bwh.harvard.edu
Krichevsky
Anna M
AM
D003594:Cytoplasmic Granules / Q000378:metabolism; D009474:Neurons / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D012323:RNA Processing, Post-Transcriptional / Q000502:physiology
D012313:RNA