title: Patients with suspected herpes simplex encephalitis: rethinking an initial negative polymerase chain reaction result.
abstract: A statewide encephalitis diagnostic project of the California State Department of Health Services found that herpes simplex virus 1 DNA may not be detectable by molecular methods early in the clinical course of herpes simplex encephalitis.
authors.affiliation: Viral and Rickettsial Disease Laboratory, Division of Communicable Disease Control, California Department of Health Services, Richmond, CA, 94804, USA.
authors.forename: Ana A
authors.initials: AA
authors.lastname: Weil
authors.forename: Carol A
authors.initials: CA
authors.lastname: Glaser
authors.forename: Zahwa
authors.initials: Z
authors.lastname: Amad
authors.forename: Bagher
authors.initials: B
authors.lastname: Forghani
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D018450:Disease Progression; D020803:Encephalitis, Herpes Simplex / Q000175:diagnosis* / Q000821:virology; D005188:False Negative Reactions; D005260:Female; D018259:Herpesvirus 1, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008403:Mass Screening; D016133:Polymerase Chain Reaction / Q000379:methods