title: Leishmania (Viannia) spp. dissemination and tissue tropism in naturally infected dogs (Canis familiaris).
abstract: First evidence is presented for Leishmania (Viannia) spp. dissemination and tissue tropism in the domestic dog. Using PCR and histology, parasites were detected in the conjunctiva, lung, lymph nodes and ovaries of 2 naturally infected Peruvian dogs. The detection of parasites in the blood indicates that parasite dissemination to those organs may have been haematogenous.
authors.affiliation: Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. rreithinger@yahoo.co.uk
authors.forename: Richard
authors.initials: R
authors.lastname: Reithinger
authors.forename: Bronwen E
authors.initials: BE
authors.lastname: Lambson
authors.forename: Douglas C
authors.initials: DC
authors.lastname: Barker
authors.forename: Helen
authors.initials: H
authors.lastname: Counihan
authors.forename: Canales Juan
authors.initials: CJ
authors.lastname: Espinoza
authors.forename: Jamintong Sabino
authors.initials: JS
authors.lastname: González
authors.forename: Clive R
authors.initials: CR
authors.lastname: Davies
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000469:parasitology*; D004285:Dogs; D005260:Female; D005355:Fibrosis / Q000469:parasitology / Q000662:veterinary; D016773:Leishmaniasis, Cutaneous / Q000469:parasitology / Q000662:veterinary*; D008099:Liver / Q000469:parasitology; D008198:Lymph Nodes / Q000469:parasitology; D010053:Ovary / Q000469:parasitology; D018512:Parasitemia / Q000175:diagnosis / Q000662:veterinary; D016133:Polymerase Chain Reaction / Q000379:methods / Q000662:veterinary; D013154:Spleen / Q000469:parasitology