[Estimation of platelet counts and their morphological parameters in patients infected by borrelia burgdorferi].
Platelet counts and their morphologic parameters in patients with Lyme borreliosis before and after antibiotic therapy (4 weeks of treatment) were estimated. 30 patients aged 17-60, x = 41 were evaluated: 7 with Erythema migrans, 3 patients with neuroborreliosis in the from Lymphocytic meningitis and 20 ones with Lyme arthritis. Control group consisted of 19 healthy persons aged 34-52, x = 43. Hematologic analyser Coulter MAXM was used for testing PLT, MPV, PCT and PDW. The results indicated that patients with Lyme boreliosis have decreasing platelet count with simultaneously increasing their volume in comparison with healthy control. It may result from the involement of platelets in defense mechanisms of infected host. The decrease of platelet count after the antibiotic treatment in comparison with the control group may be the reflection of influence of antibiotic treatment on thrombopoesis.
Zajkowska
J M
JM
Kliniki Chorób Zakaźnych i Neuroinfekcji, Białymstoku. zajkowsk@kki.net.pl
Hermanowska-Szpakowicz
T
T
Wysocka
J
J
Pancewicz
S
S
Lipska
A
A
Kasprzycka
E
E
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000097:blood* / Q000382:microbiology*; D001792:Blood Platelets / Q000473:pathology*; D025065:Borrelia burgdorferi; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D015787:Erythema Chronicum Migrans / Q000097:blood*; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000097:blood*; D020852:Lyme Neuroborreliosis / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D013997:Time Factors
D000900:Anti-Bacterial Agents
Ocena liczby płytek i ich parametrów morfologicznych u chorych zakazonych Borrelia burgdorferi.