[PCR-based detection of HLA-DQ alpha and polymarker loci and their application in forensic science].
Studies were conducted to evaluate the forensic applicability of multiplex amplification of HLA-DQ alpha and PM loci. These loci could be simultaneously typed by reverse dot blot approach where allele specific oligonucleotide probes were immobilized on a nylon membrane strip. Allele and genotype frequencies for HLA-DQ alpha and PM loci were determined in Chinese Han population. The frequency data can be used in individual identification and paternity test.
Lin
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Y
Institute of Forensic Sciences, Ministry of Justice, Shanghai, 200063.
Que
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T
Li
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L
Zhao
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Z
D005260:Female; D005554:Forensic Medicine; D005787:Gene Frequency; D005819:Genetic Markers; D006683:HLA-DQ Antigens / Q000235:genetics*; D059848:HLA-DQ alpha-Chains; D006801:Humans; D008297:Male; D021141:Nucleic Acid Amplification Techniques; D010334:Paternity
D005819:Genetic Markers; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; C069050:HLA-DQA1 antigen