Paroxysmal dystonia with thalamic lesion in multiple sclerosis.
Paroxysmal dystonia (PD) is a usually painful, unilateral dystonic posture, precipitated by voluntary movement, tactile stimulation, startling noise or hyperventilation. We describe two cases of paroxysmal dystonia in multiple sclerosis, both with a critically localized lesion in the thalamus, contralateral to the paroxysmal symptoms. Only one other case of paroxysmal dystonia with a demyelinated lesion of the thalamus has been reported previously.
Zenzola
A
A
Department of Neurological Science, Second Neurological Clinic, Policlinico, University of Bari, Italy.
De Mari
M
M
De Blasi
R
R
Carella
A
A
Lamberti
P
P
D000293:Adolescent; D004421:Dystonia / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D013786:Thalamic Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D013788:Thalamus / Q000473:pathology / Q000503:physiopathology*; D016896:Treatment Outcome