The molecular mechanism of targeted vesicle transport in cytokinesis.
Recent studies have demonstrated that vesicle transport to cleavage furrow is indispensable for cytokinesis. Some animal and plant cells form distinct structures during cell division known as central spindle and phragmoplast, respectively. Several essential factors involved in the vesicle transport have been isolated so far. SNARE proteins and molecular motors play a central role in this process. For future research of cytokinesis, it is important to investigate these factors as well as cytoskeletal components of the contractile ring in detail. This review focuses on the molecular mechanism of targeted vesicle transport in cytokinesis.
Edamatsu
M
M
Graduate School of Arts and Sciences, University of Tokyo, Japan. cedam@mail.ecc.u-tokyo.ac.jp
D000818:Animals; D001692:Biological Transport; D002455:Cell Division; D022162:Cytoplasmic Vesicles / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism; D020409:Molecular Motor Proteins / Q000378:metabolism; D050600:SNARE Proteins; D008941:Spindle Apparatus / Q000378:metabolism; D033921:Vesicular Transport Proteins
D008565:Membrane Proteins; D020409:Molecular Motor Proteins; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins