title: The importance of obesity in diabetes and its treatment with sibutramine.
abstract: Weight gain is a known risk factor for the development of type 2 diabetes and even modest weight reduction can reduce the risk of developing diabetes, so controlling body weight is an important public health goal in the fight against diabetes and its comorbidities. Weight reduction is also a cornerstone of diabetes management, improving glycaemic control and reducing other risk factors associated with this disease. Pharmacotherapies such as sibutramine contribute to the management of type 2 diabetes in overweight and obese patients.
authors.affiliation: Department of Diabetology, Metabolism and Clinical Nutrition, Faculty of Medicine, University Hospital Antwerp, Belgium. luc.van.gaal@uza.be
authors.forename: L F
authors.initials: LF
authors.lastname: Van Gaal
authors.forename: F W
authors.initials: FW
authors.lastname: Peiffer
mesh_terms: D001067:Appetite Depressants / Q000494:pharmacology / Q000627:therapeutic use*; D003503:Cyclobutanes / Q000494:pharmacology / Q000627:therapeutic use*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000517:prevention & control*; D006442:Glycated Hemoglobin / Q000187:drug effects; D006801:Humans; D009765:Obesity / Q000150:complications / Q000517:prevention & control*; D015431:Weight Loss
chemical_list: D001067:Appetite Depressants; D003503:Cyclobutanes; D006442:Glycated Hemoglobin; C058254:sibutramine