title: Perinatal arrhythmias -- diagnosis and treatment.
abstract: We did a retrospective analysis of the clinical files of 26 neonates with arrhythmia born during the period between January 1994 and February 1999. Fourteen (53.8%) of the neonates were male and 16 (61.5%) had prenatal diagnosis. Four (15.3%) had associated congenital heart disease. Twenty-one (80.7%) had abnormal rhythm and five (19.2%) had cardiac conduction disorder. Digoxin was the therapy of first choice to restore normal rhythm, used in 66.6% of the patients, followed by adenosine (16.6%) and electrical cardioversion (16.6%). An epicardial pacemaker was used in two of the three neonates with complete atrioventricular (AV) block. One neonate died due to cerebral hemorrhage. All the neonates were discharged in a clinically stable condition and 16 (88.8%) of them were medicated with digoxin. In a follow-up period that varied from 0 to 71 months (mean of 30.8 months), two patients had an episode of supraventricular tachycardia (SVT) after treatment withdrawal. Perinatal arrhythmias, although uncommon, can be life-threatening, and hence we consider our experience with these situations worth presenting.
authors.affiliation: Serviços de Cardiologia Pediátrica e Neonatologia Departamento de Pediatria do Hospital de S. João, Porto.
authors.forename: Cláudia
authors.initials: C
authors.lastname: Moura
authors.forename: António
authors.initials: A
authors.lastname: Vieira
authors.forename: Hercília
authors.initials: H
authors.lastname: Guimarães
authors.forename: José Carlos
authors.initials: JC
authors.lastname: Areias
mesh_terms: D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies