Forecasting the oral absorption behavior of poorly soluble weak bases using solubility and dissolution studies in biorelevant media.
Kostewicz
Edmund S
ES
Institut für Pharmazeutische Technologie. J. W. Goethe Universität, Frankfurt am Main, Germany.
Brauns
Ulrich
U
Becker
Robert
R
Dressman
Jennifer B
JB
D000284:Administration, Oral; D001562:Benzimidazoles / Q000737:chemistry / Q000493:pharmacokinetics; D005544:Forecasting / Q000379:methods*; D006878:Hydroxides / Q000737:chemistry / Q000493:pharmacokinetics; D007408:Intestinal Absorption / Q000502:physiology; D012995:Solubility / Q000187:drug effects; D013656:Taurocholic Acid / Q000737:chemistry / Q000493:pharmacokinetics
D001562:Benzimidazoles; D006878:Hydroxides; C098107:flibanserin; D013656:Taurocholic Acid