title: Intrauterine left chamber myocardial infarction of the heart and hydrops fetalis in the recipient fetus due to twin-to-twin transfusion syndrome.
abstract: A rare complication of twin-to-twin transfusion syndrome (TTTS) is described: myocardial infarction of the recipient fetus. Myocardial infarction and hydrops are considered to be consequences of hypertension in the recipient. No other organs were affected. Pathological signs of intrauterine hypertension were estimated by the thickness of vessel walls and signs of hypertrophied myocardial cells. In the heart of the recipient fetus there was a chronic myocardial infarction near the apex cordis on the anterior wall with an aneurysm 4x5 mm in diameter. Diagnosis was based on light microscopic examination. The poor myocardial systolic function resulted in hydrops. Since the mother was administered beta sympathomimetics in therapeutic doses the contribution of the drug to the myocardial infarction is uncertain, but we would like to suggest this as a possible adverse effect in TTTS. The present case is the first reported myocardial infarction in connection with the syndrome.
authors.affiliation: 1st Department of Obstetrics and Gynaecology, Semmelweis University Budapest, Hungary. Tamas.Marton@bhamwomens.thenhs.com
authors.forename: Tamás
authors.initials: T
authors.lastname: Marton
authors.forename: Júlia
authors.initials: J
authors.lastname: Hajdú
authors.forename: Ervin
authors.initials: E
authors.lastname: Hruby
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Papp
mesh_terms: D000318:Adrenergic beta-Agonists / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D005260:Female; D005330:Fetofetal Transfusion / Q000150:complications* / Q000473:pathology; D006801:Humans; D015160:Hydrops Fetalis / Q000150:complications*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications* / Q000473:pathology; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D012312:Ritodrine / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000318:Adrenergic beta-Agonists; D012312:Ritodrine