[Role of polypeptide growth factors in the regulation of epidermal keratinocyte proliferation].
The growth factors, cytokines, adhesive molecules and extracellular matrix components play the leading role in the processes of intercellular interactions. Literary data on structure and mechanisms of functioning of the growth factors and their receptors are summarised in the present review. Some aspects of regulatory functions of such growth factors as EGF, TGFalpha, TGFbeta, FGF, KGF, AR, and HGF in these processes in epidermis keratinocytes both in vivo and in vitro as example were also considered.
Gusak
V K
VK
Vasil'ev
R G
RG
Zubov
D A
DA
Slipchenko
I O
IO
Korchak
O M
OM
Popandopulo
A G
AG
D000818:Animals; D002455:Cell Division / Q000502:physiology; D006133:Growth Substances / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D015603:Keratinocytes / Q000502:physiology*; D010455:Peptides / Q000378:metabolism*; D017978:Receptors, Growth Factor / Q000378:metabolism
D006133:Growth Substances; D010455:Peptides; D017978:Receptors, Growth Factor
Rol' polipeptidnykh faktorov rosta v reguliatsii proliferatsii keratinotsitov epidermisa.