title: A motivational intervention to improve adherence to treatment of chronic disease.
abstract: OBJECTIVE
  To describe an approach to intervention, based on Motivational Interviewing (MI) and the Transtheoretical Model (TTM) of Change that allows the health care provider to support medication adherence in a client-centered fashion.
  
  
  METHODS
  Review of selected research-based and theoretical articles on MI, TTM, and medication compliance issues.
  
  
  CONCLUSIONS
  Adherence is a complex phenomenon that requires a personalized intervention. The response must focus on clients' readiness to adhere, their sense of self-efficacy in taking medicines in all circumstances, and their personal pros and cons related to adherence.
  
  
  CONCLUSIONS
  Adherence to complex medication regimens is important to long-term treatment of chronic diseases, such as HIV disease. Adherence in HIV is particularly critical to adequately suppress viral replication as well as to prevent opportunistic infections.
authors.affiliation: University of Mississippi, Division of Infectious Diseases, University of Mississippi Medical Center, USA. dkparker@medicine.umsmed.edu
authors.forename: D J
authors.initials: DJ
authors.lastname: Konkle-Parker
mesh_terms: D002908:Chronic Disease / Q000188:drug therapy / Q000451:nursing; D015658:HIV Infections / Q000188:drug therapy / Q000451:nursing; D006801:Humans; D007407:Interviews as Topic; D009042:Motivation; D010349:Patient Compliance; D010353:Patient Education as Topic; D011320:Primary Health Care; D011369:Professional-Patient Relations; D020377:Self Efficacy