title: [Pharma clinics. Medication of the month. Imiquimod (Aldara): an immunomodulator for the skin].
abstract: Imiquimod is the first drug of a new therapeutic class encompassing cutaneous immune response modifiers. This molecule induces the synthesis and release of macrophage-related cytokines. It boosts some local immune responses. These properties are used to treat cutaneous viral condylomas. Other prospective therapeutic goals are presently scrutinized.
authors.affiliation: Service de Dermatopathologie, Université de Liège.
authors.forename: T
authors.initials: T
authors.lastname: Hermanns-Lê
authors.forename: A F
authors.initials: AF
authors.lastname: Nikkels
authors.forename: I
authors.initials: I
authors.lastname: Uhoda
authors.forename: L
authors.initials: L
authors.lastname: Petit
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology* / Q000627:therapeutic use; D000634:Aminoquinolines / Q000494:pharmacology* / Q000627:therapeutic use; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D000077271:Imiquimod; D008264:Macrophages / Q000276:immunology; D012871:Skin Diseases / Q000188:drug therapy* / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D016207:Cytokines; D000077271:Imiquimod
vernacular_title: Pharma clinics. Le médicament du mois. L'imiquimod (Aldara): un immunomodulateur pour la peau.