Limited clinical utility of high-sensitivity plasma C-reactive protein assays.
Many recent studies have shown a relationship between plasma C-reactive protein (CRP) concentrations and risk of cardiovascular disease. However, the intra-individual variation in plasma CRP concentrations is large. Use of plasma CRP measurement in individual patients is likely to result in many being misclassified in their risk status. Use of repeated measurements is not a practical solution to this problem.
Campbell
Bruce
B
Sullivan Nicolaides Pathology Indooroopilly QLD, Australia. B_Campbell@snp.com.au
Badrick
Tony
T
Flatman
Robert
R
Kanowski
David
D
D002097:C-Reactive Protein / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000378:metabolism; D003951:Diagnostic Errors; D006801:Humans; D012307:Risk Factors
D002097:C-Reactive Protein