[Effects of taurine and extraction of cristata L on serum Zn, Cu and Ca in rats].
Forty rats fed with basic diets were randomly divided into 4 groups. NG group were fed with basic diets. The other three groups were fed with high fat diets. The rats in TA group and EC group were given TA 100 mg/kg or EC 100 mg/kg each day respectively in addition to high fat diet for 8 weeks. The results showed that taurine and extraction of cristata L not only increased the level of red cell SOD and the content of serum Zn (P < 0.05), but also decreased the contents of TC, MDA in the wall of artery and decreased the level of serum LDH significantly (P < 0.05 or P < 0.01). TA and EC increased significantly the content of serum Cu and decreased the ratio of serum Cu to Zn in the high fat diet rats (P < 0.01), and decreased the contents of serum Ca also. The results indicate that TA and EC may play some role in lipid metabolism and inhibit atherosclerosis by regulating the levels of Zn, Cu and Ca in rats.
Li
W
W
Department of Preventive Medicine, Xinxiang Medical College, Xinxiang 453003, China.
Tian
Y
Y
Feng
H
H
Tu
B
B
D000818:Animals; D002118:Calcium / Q000097:blood*; D002784:Cholesterol / Q000378:metabolism; D003300:Copper / Q000097:blood*; D006949:Hyperlipidemias / Q000097:blood; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013654:Taurine / Q000494:pharmacology*; D015032:Zinc / Q000097:blood*
D010936:Plant Extracts; D013654:Taurine; D003300:Copper; D002784:Cholesterol; D015032:Zinc; D002118:Calcium