A case of metastatic extra-adrenal pheochromocytoma 12 years after surgery.
At the age of 53, a 65-year-old man had been diagnosed with extra-adrenal pheochromocytoma in the retroperitoneum and underwent total tumorectomy. Afterward, he had his serum catecholamine periodically measured in an outpatient clinic. In February 1999, 12 years after surgery, he complained of lower left abdominal pain. Computed tomography and magnetic resonance imaging revealed an osteolytic lesion in thoracic vertebrae 11Th (Th 11). Although his basal serum and urine catecholamines were at normal levels, glucagon injection increased blood pressure and plasma catecholamine levels. 131I-metaiodobenzylguanidine (MIBG) scintigraphy was specifically taken up to Th 11. By bone biopsy, the osteolytic lesion in Th 11 was finally diagnosed with metastasis of pheochromocytoma. For post-operative pheochromocytoma, long-term follow-up involving biochemical tests, including serum catecholamines, and MIBG is needed.
Mori
Shunsuke
S
Second Department of Internal Medicine, Ehime University School of Medicine, Japan.
Okura
Takafumi
T
Kitami
Yutaka
Y
Takata
Yasunori
Y
Nakamura
Michitsugu
M
Watanabe
Sanae
S
Iwata
Takeru
T
Hiwada
Kunio
K
D019797:3-Iodobenzylguanidine; D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010673:Pheochromocytoma / Q000175:diagnosis / Q000556:secondary*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013904:Thoracic Vertebrae; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine