title: [Ultrastructure changes of liver autolysis].
abstract: Ultra-structure changes of autolysis of hepatocyte were studied using transmission electron microscope(TEM). It was found that autolysis started 0.5 hour after death, with the heterochromatin of nuclei shrinking abnormally and smooth endoplasmic reticulum expanding. The changes developed to distinction after 1 h, and progressed continuously after 2 h, 3 h, 4 h and 5 h. It was found that (1) the mitochondria were swelling, its matrix density decreasing and flocculent dense bodies (FDB) emerging; (2) the rough endoplasmic reticulum and perinuclear cistern were expanding. It was suggested that ultra-structure changes of the autolysis be correlated to the postmortem time.
authors.affiliation: Institute of Forensic Sciences, Ministry of Justice, PR. China, Shanghai 200063.
authors.forename: Z
authors.initials: Z
authors.lastname: Qing
authors.forename: Y
authors.initials: Y
authors.lastname: Gong
authors.forename: Y
authors.initials: Y
authors.lastname: Yu
mesh_terms: D001329:Autolysis / Q000473:pathology*; D005554:Forensic Medicine; D022781:Hepatocytes / Q000648:ultrastructure*; D006801:Humans; D008875:Middle Aged; D013997:Time Factors