title: Computing DIT from energy expenditure measures in a respiratory chamber: a direct modeling method.
abstract: The possibility of computing Diet Induced Thermogenesis (DIT) is an important feature of metabolic investigations. However, methodological problems have affected the determination of DIT in the indirect calorimetric chamber. DIT has been commonly estimated by regressing energy expenditure on a measure of physical activity. Although used for many years as the only feasible approach to calculate DIT in a respiratory chamber, this traditional method has been criticized because of an apparent underestimation of the DIT, but no alternative method has been suggested so far. The present work proposes to estimate DIT directly by means of a mathematical model. This approach also allows to simultaneously estimate other parameters, namely resting energy expenditure (REE), physical activity (PA) and physical exercise (PE).
authors.affiliation: CNR, Centro Fisiopatologia Shock, Laboratorio di Biomatematica, Roma, Italy. simeonem@umich.edu
authors.forename: S
authors.initials: S
authors.lastname: Marino
authors.forename: A
authors.initials: A
authors.lastname: De Gaetano
authors.forename: A
authors.initials: A
authors.lastname: Giancaterini
authors.forename: D
authors.initials: D
authors.lastname: Giordano
authors.forename: M
authors.initials: M
authors.lastname: Manco
authors.forename: A V
authors.initials: AV
authors.lastname: Greco
authors.forename: G
authors.initials: G
authors.lastname: Mingrone
mesh_terms: D000328:Adult; D000886:Anthropometry; D002153:Calorimetry, Indirect; D002940:Circadian Rhythm / Q000502:physiology; D003198:Computer Simulation; D004734:Energy Metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008432:Mathematical Computing; D008875:Middle Aged; D009767:Obesity, Morbid / Q000503:physiopathology; D022722:Thermogenesis / Q000502:physiology*