title: [Effectiveness of zopiclone in disorders of initiating and maintaining sleep. Results of a drug monitoring study in 811 general practices].
abstract: METHODS
  In a drug monitoring study with 811 participating general practitioners, safety and tolerability of zopiclone were studied in 2416 patients with disorders of initiating and maintaining sleep.
  
  
  RESULTS
  In general, zopiclone was efficient in all forms of insomnia; the subjective sleep duration was prolonged for 2 hours on average. Patients without somatic complaints or comorbidity showed the greatest benefit. Daytime well-being and vigilance were in general not impaired. Drug related adverse events occurred rarely; the great majority of the participating physicians rated the treatment with zopiclone as efficient and acceptable.
  
  
  CONCLUSIONS
  In this drug monitoring study, zopiclone proved an efficient hypnotic for the treatment of disorders of initiating and maintaining sleep.
authors.affiliation: Klinik und Poliklinik für Psychiatrie und Psychotherapie der Technischen Universität München.
authors.forename: M H
authors.initials: MH
authors.lastname: Wiegand
authors.forename: G
authors.initials: G
authors.lastname: Roszinsky-Köcher
authors.forename: B
authors.initials: B
authors.lastname: Schwalb
authors.forename: W
authors.initials: W
authors.lastname: Fischer
authors.forename: M W
authors.initials: MW
authors.lastname: Eckert
mesh_terms: D000328:Adult; D000368:Aged; D053961:Azabicyclo Compounds; D003627:Data Interpretation, Statistical; D016903:Drug Monitoring; D005194:Family Practice; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007319:Sleep Initiation and Maintenance Disorders / Q000175:diagnosis / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone
vernacular_title: Die Effektivität von Zopiclon bei Ein- und Durchschlafstörungen. Ergebnisse einer Anwendungsbeobachtung in 811 Hausarztpraxen.