Two successful cases of bromide therapy for refractory symptomatic localization-related epilepsy.
Potassium bromide was tried for two children with daily convulsive focal motor seizures with unconsciousness and focal motor seizure status. The treatment resulted in complete cessation of the attacks. It has been reported that bromide is effective for generalized tonic-clonic seizures and not for complex partial seizures, such as convulsive focal motor seizures with unconsciousness. However, our experiences provide evidence that bromide is one of the useful therapeutic agents for intractable symptomatic localization-related epilepsy.
Takayanagi
Masaru
M
Department of Pediatrics, Sendai City Hospital, 3-1 Shimizukoji, Wakabayashi-ku, Sendai, Miyagi, Japan. mtakayanagi@ped.med.tohoku.ac.jp
Yamamoto
Katsuya
K
Nakagawa
Hiroshi
H
Munakata
Mitsutoshi
M
Kato
Rie
R
Yokoyama
Hiroyuki
H
Haginoya
Kazuhiro
K
Iinuma
Kazuie
K
D001965:Bromides / Q000627:therapeutic use*; D002648:Child; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D017680:Potassium Compounds / Q000627:therapeutic use*; D016896:Treatment Outcome; D014474:Unconsciousness
D001965:Bromides; D017680:Potassium Compounds; C039004:potassium bromide