title: Early and late outcomes in patients with severe extracranial internal carotid stenosis undergoing carotid endarterectomy.
abstract: OBJECTIVE
  To determine the perioperative and late outcomes for carotid endarterectomy (CEA) in treatment of patients with high-grade stenotic lesions of the extracranial internal carotid artery.
  
  
  METHODS
  Twenty patients underwent 21 CEAs at the Zhongshan Hospital between May 1993 and June 2000. They were 19 men and 1 woman, with a mean age of 64 +/- 9 years. Seven patients were performed for stroke, 11 for transient ischaemic attacks (TIAs) and 2 for asymptomatic disease. Duplex scan was the primary tool of evaluation prior to surgery. Perioperative digital subtraction angiography and magnetic resonance angiography were done for 19 and 18 patients, respectively. The percentage of stenosis was calculated using NASCET criteria. Of the 21 lesions operated, 19 had a stenosis of 70% or greater, 2 had ulcerative lesions with a stenosis ranging from 60% to 69%. All CEAs were performed under cervical block anaesthesia with selective intraoperative shunting and patch angioplasty. The patients were followed up regularly with duplex scan surveillance.
  
  
  RESULTS
  There was no mortality or stroke during 30 days postoperatively. A TIA occurred in one patient and cranial nerve injury in 2 patients perioperatively. All patients were followed up for a mean interval of 31 +/- 20 months (range: 1 - 63 months). The 2-year survival rate and risk of stroke were 92.3% and 0%, respectively, and the 5-year survival rate and risk of stroke were 79.1% and 12.5%, respectively. Two asymptomatic recurrent stenoses ranging from 50% to 60% were detected on follow-up duplex scan.
  
  
  CONCLUSIONS
  For the patients in this study, CEA is associated with an acceptable perioperative outcome as well as a satisfactory long-term beneficial effect in stroke prevention.
authors.affiliation: Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China. guodaqiao@sina.com
authors.forename: Daqiao
authors.initials: D
authors.lastname: Guo
authors.forename: Yuqi
authors.initials: Y
authors.lastname: Wang
authors.forename: Weiguo
authors.initials: W
authors.lastname: Fu
authors.forename: Jianrong
authors.initials: J
authors.lastname: Ye
authors.forename: Fuzhen
authors.initials: F
authors.lastname: Chen
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
mesh_terms: D000368:Aged; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000601:surgery*; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome