[Syndecan-1 (CD138): an immunohistochemical marker of plasma cell tumors].
The immunohistochemical detection of syndecan-1 (belonging to the cluster CD138) is a sensitive and reliable method for identifying normal and neoplastic plasma cells. It may be used in paraffin-embedded bone marrow specimens, as well as in extramedullary tumours of unknown origin. The three anaplastic tumours reported by us in the lymph node, the gingiva, and pleura were negative for other markers, but the syndecan-1 positivity elucidated their plasmocytic histogenesis.
Fakan
F
F
Siklův patologicko-anatomický ústav Lékarské fakulty UK a Fakultní nemocnice, Plzen.
Boudová
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L
Hejda
C
C
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008562:Membrane Glycoproteins / Q000032:analysis*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000737:chemistry / Q000175:diagnosis; D010954:Plasmacytoma / Q000737:chemistry / Q000175:diagnosis*; D011509:Proteoglycans / Q000032:analysis*; D053668:Syndecan-1; D053667:Syndecans
D014408:Biomarkers, Tumor; D008562:Membrane Glycoproteins; D011509:Proteoglycans; C508241:SDC1 protein, human; D053668:Syndecan-1; D053667:Syndecans
Syndecan-1 (CD138): imunohistochemický marker nádorů z plazmatických bunĕk.