[Circadian and ultradian cycles in narcolepsy].
In narcolepsy, homeostatic process is preserved while sleep/wake circadian process is impaired. Other circadian components (body temperature, endocrine secretions, subjective sleepiness) are preserved. This circadian system weakness permits the occurrence of a very strong ultradian component, modulating sleep/wake rhythm. So, a 4 hour ultradian rhythmicity of Slow Wave Activity, and a 2 hour NREM/REM cycle longer than in normal subjects, has been evidenced in narcoleptic patients. These circadian and ultradian alterations can explain a major part of the narcoleptic symptoms.
Espa
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INSERM E-9930, Hôpital La Colombière, Montpellier Service de Neurologie B, Hôpital Gui de Chauliac, Montpellier.
Besset
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A
D000204:Activity Cycles / Q000502:physiology*; D001921:Brain / Q000503:physiopathology; D002940:Circadian Rhythm / Q000502:physiology*; D004569:Electroencephalography; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D009290:Narcolepsy / Q000503:physiopathology*; D012894:Sleep Stages / Q000502:physiology*
Processus ultradien et circadien dans la narcolepsie.