Chloramphenicol in the 21st century.
Chloramphenicol use has declined in the UK, despite it remaining highly active against a wide range of bacteria. This article will review the activity, pharmacology, toxicology, uses and potential uses of chloramphenicol in an era of increasing antimicrobial resistance.
Wareham
David W
DW
London and Newham NHS Trusts, Department of Medical Microbiology, Royal London Hospital, London E1 1BB.
Wilson
Peter
P
D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy*; D002701:Chloramphenicol / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D002702:Chloramphenicol Resistance; D006801:Humans; D011500:Protein Synthesis Inhibitors / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D011500:Protein Synthesis Inhibitors; D002701:Chloramphenicol