title: Searching for the mountains of the moon: genome scans for atherosclerosis.
abstract: Several research groups have begun mounting large, ambitious family studies to map genes for atherosclerosis, heart disease, and their major risk factors using whole genome linkage and/or disequilibrium scans. Some of the problems, pitfalls, and challenges of this exciting effort are examined and illustrated with lessons from an earlier mapping problem.
authors.affiliation: Division of Biostatistics, Washington University School of Medicine, 660 South Euclid, Box 8067, St. Louis, MO 63110, USA. mike@wubios.wustl.edu
authors.forename: Michael A
authors.initials: MA
authors.lastname: Province
mesh_terms: D001161:Arteriosclerosis / Q000235:genetics*; D002874:Chromosome Mapping / Q000379:methods*; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006331:Heart Diseases / Q000235:genetics; D006801:Humans