title: A study of glaucoma after penetrating keratoplasty.
abstract: OBJECTIVE
  To identify the incidence and risk factors associated with the development of glaucoma after penetrating keratoplasty.
  
  
  METHODS
  A retrospective study was carried out in 228 patients who underwent penetrating keratoplasty from January 1995 to January 2000 at the Cornea Section of the Ophthalmology Service at the School of Medicine, Federal University of Uberlândia MG, Brazil. Follow-up time ranged from 4 to 60 months (mean, 17.14 +/- 13.65).
  
  
  RESULTS
  Two hundred twenty-eight patients undergoing penetrating keratoplasty were evaluated and 49 (21.5%) developed glaucoma. Risk factors for developing glaucoma were bullous keratopathy [relative risk (RR) = 2.1774), herpesvirus (RR = 1.8979), and trauma (RR = 1.0575). Mean intraocular pressure before transplantation was 15.26 +/- 5.37 mm Hg. Intraocular pressure after transplantation ranged from 22 to 58 mm Hg, with a mean value of 30.04 +/- 7.06 mm Hg. Thirty-six (73.5%) patients had medical treatment, 10 (20.4%) had medical and surgical treatment, and three (6.1%) had surgical treatment. Final intraocular pressure ranged from 4 to 34 mm Hg (mean, 16.79 +/- 5.36).
  
  
  CONCLUSIONS
  The incidence of glaucoma after penetrating keratoplasty is high, and the risk factors include aphakic/pseudophakic bullous keratopathy, herpes simplex virus, and trauma.
authors.affiliation: Department of Ophthalmology, School of Medicine, Federal University of Uberlândia, Minas Gerais, Brazil. franca@centershop.com.br
authors.forename: Edimar Tiago
authors.initials: ET
authors.lastname: França
authors.forename: Enyr Saran
authors.initials: ES
authors.lastname: Arcieri
authors.forename: Rafael Saran
authors.initials: RS
authors.lastname: Arcieri
authors.forename: Flavio Jaime
authors.initials: FJ
authors.lastname: Rocha
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005901:Glaucoma / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors