title: [The antioxidative effect of procyanidins from pine bark in vitro].
abstract: OBJECTIVE
  To assess the antioxidative effect of procyanidins from pine bark on free radical damage.
  
  
  METHODS
  Hemolysis, Malonaldehyde(MDA) level of mice liver homogenates, the conformation changes of irradiated plasmid PUC18 were used as indexes.
  
  
  RESULTS
  Procyanidins could reduce the hemolysis degree of human RBC induced by H2O2 significantly(P < 0.01), reduce the MDA level of mice liver homogenate initiated by VitC/Fe2+ remarkably(P < 0.01), and reduce the degree of single-strain break of plamid PUC18 induced by 60Co gamma significantly(P < 0.01).
  
  
  CONCLUSIONS
  Procyanidins had good antioxidative function. It can prevent RBC membrane, plasmid DNA suffering from oxygen free radical damage in vitro.
authors.affiliation: Medical College of Jinan University, Guangzhou 510632.
authors.forename: C
authors.initials: C
authors.lastname: Lin
authors.forename: J
authors.initials: J
authors.lastname: Jiang
authors.forename: M
authors.initials: M
authors.lastname: Wu
authors.forename: Y
authors.initials: Y
authors.lastname: Yan
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D044946:Biflavonoids; D002392:Catechin / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects*; D008099:Liver / Q000737:chemistry; D008315:Malondialdehyde / Q000032:analysis; D051379:Mice; D028223:Pinus / Q000737:chemistry*; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology; D010957:Plasmids / Q000032:analysis; D044945:Proanthocyanidins
chemical_list: D000975:Antioxidants; D044946:Biflavonoids; D010936:Plant Extracts; D044945:Proanthocyanidins; C017674:procyanidin; D008315:Malondialdehyde; D002392:Catechin