Antiinflammatory property of the leaves of Gongronema latifolium.
An aqueous extract of the dried leaves of Gongronema latifolium was studied for its antiinflammatory activity. The extract significantly (p < 0.05) inhibited carrageenan-induced rat paw oedema, carrageen-induced leucocyte migration in rats and dye leakage induced by intraperitoneal injection of acetic acid in mice. These results demonstrate the antiinflammatory property of G. latifolium.
Morebise
Olugbenga
O
Department of Biochemistry, College of Health Sciences, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
Fafunso
Michael A
MA
Makinde
J Modupe
JM
Olajide
Olumayokun A
OA
Awe
E O
EO
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D029062:Apocynaceae; D002199:Capillary Permeability / Q000187:drug effects; D002351:Carrageenan; D002464:Cell Migration Inhibition; D004305:Dose-Response Relationship, Drug; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control*; D005260:Female; D008297:Male; D051379:Mice; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts; D002351:Carrageenan