title: [Assessment of left ventricular function by thallium-201 quantitative gated cardiac SPECT].
abstract: OBJECTIVE
  Present study was designed to evaluate the accuracy of the measurement of left ventricular volume by quantitative gated SPECT (QGS) software using 201T1 and the effect of cutoff frequency of Butterworth prereconstruction filter on the calculation of volume.
  
  
  METHODS
  The RH-2 type cardiac phantom and 20 patients with ischemic heart disease were studied. Left ventricular end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF) were calculated by the QGS software using the various frequency of Butterworth filter. These parameters were evaluated by Simpson's method using left ventriculography (LVG).
  
  
  RESULTS
  The volume of the phantom calculated by QGS was under-estimated by 14%. In the clinical study, EDV and ESV measured by QGS were smaller than those obtained from LVG by 10%. When the cutoff frequency of Butterworth filter was 0.43 cycles/cm, the values measured by QGS were best correlated with those by LVG (EDV: r = 0.80, p < 0.001; ESV: r = 0.86, p < 0.001; EF: r = 0.80, p < 0.001).
  
  
  CONCLUSIONS
  These data suggest that 201Tl quantitative gated cardiac SPECT can estimate myocardial ischemia and left ventricular function simultaneously.
authors.affiliation: Department of Cardiovascular Medicine, Wakayama Medical University. babakira@wakayama-med.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Baba
authors.forename: Takuzo
authors.initials: T
authors.lastname: Hano
authors.forename: Hisashi
authors.initials: H
authors.lastname: Ohmori
authors.forename: Masayo
authors.initials: M
authors.lastname: Ibata
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kawabe
authors.forename: Takashi
authors.initials: T
authors.lastname: Kubo
authors.forename: Keizo
authors.initials: K
authors.lastname: Kimura
authors.forename: Ichiro
authors.initials: I
authors.lastname: Nishio
mesh_terms: D000328:Adult; D000368:Aged; D004569:Electroencephalography; D005260:Female; D015637:Gated Blood-Pool Imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000503:physiopathology; D019047:Phantoms, Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D012984:Software; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D016277:Ventricular Function, Left
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes