title: Progress of visual dysfunction in Parkinson's disease.
abstract: Studies on progression of Parkinson's disease (PD) mainly focus on the nigrostriatal dopaminergic decline, but not on the visual system. We determined progression of (i) disturbed color vision, assessed with the Farnsworth-Munsell 100 Hue test (FMT) and (ii) intensity of PD in 18 patients. Significant differences occurred between (i) initial FMT error scores and follow-up results 3 years later (P=0.002) and analogously (ii) scored intensity of PD (P=0.002). A relation between computed differences of FMT error scores and rated activities of daily living appeared. Deterioration of color vision progresses in PD.
authors.affiliation: Department of Neurology, St Josef-Hospital, Ruhr-University of Bochum, 44791 Bochum, Germany. thomas.mueller@ruhr-uni-bochum.de
authors.forename: T
authors.initials: T
authors.lastname: Müller
authors.forename: D
authors.initials: D
authors.lastname: Woitalla
authors.forename: S
authors.initials: S
authors.lastname: Peters
authors.forename: K
authors.initials: K
authors.lastname: Kohla
authors.forename: H
authors.initials: H
authors.lastname: Przuntek
mesh_terms: D003118:Color Perception; D003119:Color Perception Tests; D003117:Color Vision Defects / Q000145:classification / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D018450:Disease Progression; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000503:physiopathology*