title: Prevalence of Helicobacter pylori in the residual stomach after gastrectomy for gastric cancer.
abstract: OBJECTIVE
  In recent years, the role of Helicobacter pylori in gastritis of the residual stomach has attracted much attention. We investigated the prevalence of Helicobacter pylori in the residual stomach after distal gastrectomy for gastric cancer, as well as the correlations between Helicobacter pylori positivity and clinical characteristics or the severity of gastritis in the residual stomach.
  
  
  METHODS
  The subjects were 66 patients with gastric cancer who underwent distal gastrectomy with Billroth I reconstruction at our department. Helicobacter pylori was detected by the 13C-urea breath test, and patients were considered to be Helicobacter pylori-positive if the delta 13C value was > 2.5@1000.
  
  
  RESULTS
  The overall Helicobacter pylori positivity rate of the gastrectomy patients was a high 80.3%, with the rate being especially high in patients under 60 years of age and in those tested less than 5 years after surgery. There was a close relationship between Helicobacter pylori positivity and the severity of gastritis.
  
  
  CONCLUSIONS
  Helicobacter pylori infection appears to cause the development of gastritis. Helicobacter pylori eradication needs to be taken into consideration in the management of Helicobacter pylori-positive patients after gastrectomy.
authors.affiliation: Department of Surgery, Tokyo Women's Medical University, Daini Hospital, 2-1-10 Nishiogu, Arakawa-ku, Tokyo 116-8567, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Katsube
authors.forename: Kenji
authors.initials: K
authors.lastname: Ogawa
authors.forename: Kanako
authors.initials: K
authors.lastname: Hamaguchi
authors.forename: Minoru
authors.initials: M
authors.lastname: Murayama
authors.forename: Soichi
authors.initials: S
authors.lastname: Konnno
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shimakawa
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Naritaka
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Yagawa
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Kajiwara
authors.forename: Motohiko
authors.initials: M
authors.lastname: Aiba
mesh_terms: D000367:Age Factors; D000368:Aged; D001944:Breath Tests; D002247:Carbon Isotopes; D005260:Female; D005743:Gastrectomy; D018530:Gastric Stump; D005756:Gastritis / Q000382:microbiology*; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*; D014508:Urea
chemical_list: D002247:Carbon Isotopes; D014508:Urea