title: Use of medroxyprogesterone acetate in the treatment of Müllerian adenosarcoma: a case report.
abstract: BACKGROUND
  Müllerianadenosarcoma is a rare pelvic malignancy that most commonly arises from the endometrium. These tumors are relatively insensitive to chemotherapy and radiation and are primarily treated by surgical resection. We report a case of müllerian adenosarcoma arising outside of the uterus from a background of endometriosis treated with a combination of surgical resection and medroxyprogesterone acetate.
  
  
  METHODS
  A 43-year-old woman with a history of endometriosis was diagnosed with advanced extrauterine müllerian adenosarcoma. After suboptimal tumor dubulking surgery she was treated with medroxyprogesterone acetate. Ten months postoperatively she remains without evidence of disease.
  
  
  CONCLUSIONS
  Medroxyprogesterone acetate may be a useful drug in the treatment of advanced müllerian adenosarcoma.
authors.affiliation: Division of Gynecologic Oncology, New York University School of Medicine, New York, New York 10016, USA. hinesb@alum.mit.edu
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Hines
authors.forename: Robert F
authors.initials: RF
authors.lastname: Porges
authors.forename: Kush
authors.initials: K
authors.lastname: Mittal
authors.forename: Franco M
authors.initials: FM
authors.lastname: Muggia
authors.forename: John P
authors.initials: JP
authors.lastname: Curtin
mesh_terms: D018195:Adenosarcoma / Q000188:drug therapy* / Q000601:surgery; D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004715:Endometriosis / Q000150:complications; D005260:Female; D005833:Genital Neoplasms, Female / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000627:therapeutic use*; D018200:Mixed Tumor, Mullerian / Q000188:drug therapy* / Q000601:surgery
chemical_list: D018931:Antineoplastic Agents, Hormonal; D017258:Medroxyprogesterone Acetate