title: Primary signet ring cell carcinoma of the urinary bladder successfully treated with intra-arterial chemotherapy alone.
abstract: A 65-year-old man presented with the complaint of gross hematuria. Cystoscopy revealed a sessile tumor on the left bladder wall. It was diagnosed as primary signet ring cell carcinoma of the bladder (T3bN0M0). The patient did not want surgical treatment. Therefore, three courses of arterial infusion of carboplatin were administered at 3-week intervals. Complete remission was obtained and has been maintained for 44 months. Our case appears to be the first report of successful treatment with chemotherapy alone of an infiltrating signet ring cell carcinoma of the bladder.
authors.affiliation: Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hirano
authors.forename: Kazuo
authors.initials: K
authors.lastname: Suzuki
authors.forename: Kimio
authors.initials: K
authors.lastname: Fujita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furuse
authors.forename: Ken
authors.initials: K
authors.lastname: Fukuta
authors.forename: Motoaki
authors.initials: M
authors.lastname: Kitagawa
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Aso
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D016190:Carboplatin / Q000627:therapeutic use*; D018279:Carcinoma, Signet Ring Cell / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin