title: Primary Sjögren's syndrome initially manifested by optic neuritis: MRI findings.
abstract: We herein describe the MRI findings in a patient clinically diagnosed with primary Sjögren's syndrome (SjS) initially manifested by retrobulbar optic neuritis. A 63-year-old woman suddenly had left ocular pain and progressive visual disturbance. MR T2-weighted images revealed hyperintensity in the left optic nerve, with swelling. Contrast-enhanced T1-weighted images showed no abnormal enhancement. Follow-up MRI 6 months after admission revealed no significant changes in the affected optic nerve. To our knowledge, optic neuritis as a complication of SjS has been reported in ten patients [1, 2, 3, 4, 5, 6] and MRI findings in only one of them [6]. We thought MR images were useful for visualizing optic nerve involvement in SjS and observing its course.
authors.affiliation: Department of Radiology, National Defense Medical College, Tokorozawa-City, Saitama, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kadota
authors.forename: A M
authors.initials: AM
authors.lastname: Tokumaru
authors.forename: K
authors.initials: K
authors.lastname: Kamakura
authors.forename: S
authors.initials: S
authors.lastname: Kohyama
authors.forename: H
authors.initials: H
authors.lastname: Okizuka
authors.forename: T
authors.initials: T
authors.lastname: Kaji
authors.forename: S
authors.initials: S
authors.lastname: Kusano
mesh_terms: D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009900:Optic Nerve / Q000473:pathology; D009902:Optic Neuritis / Q000150:complications / Q000175:diagnosis*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis