title: Developments in ion mobility spectrometry-mass spectrometry.
abstract: Ion mobility spectrometry (IMS) has been used for over 30 years as a sensitive detector of organic compounds. The following is a brief review of IMS and its principles with an emphasis on its usage when coupled to mass spectrometry. Since its inception, IMS has been interfaced with quadrupole, time-of-flight, and Fourier-transform ion cyclotron resonance mass spectrometry. These hybrid instruments have been employed for the analysis of a variety of target analytes, including biomolecules, explosives, chemical warfare degradation products, and illicit drugs.
authors.affiliation: Weber State University, Department of Criminal Justice, Ogden, Utah 84408-1206, USA.
authors.forename: D C
authors.initials: DC
authors.lastname: Collins
authors.forename: M L
authors.initials: ML
authors.lastname: Lee