[Effect of hyperlipidemia on auditory brain stem responses].
OBJECTIVE
To investigate the effects of increasing stimulus rate (ISR) of sound stimulation in ABR test and obtain experimental data for clinical use on the early diagnosis of hyperlipidemia (HL), neurologically and audiologically asymptomatic patients.


METHODS
30 random samples of HL patients who have normal blood pressure and no symptoms of circulatory system and nerve system were selected. As control group, another 30 men were selected. The clicks stimuli were presented at rates of 10/s and 50/s respectively in ABR test.


RESULTS
By the "ABR 10/s test" mode, the ABR showed no differences between two groups (P > 0.05). The net effect of ISR (50/s) on interpeak latency difference (IPLD) of ABR was significantly greater in the hyperlipidemic patients for IPLD(I-V) and IPLD(I-III). In HL group, the effects were compared between retina angiosclerosis patients and no retina angiosclerosis patients and the same result was observed.


CONCLUSIONS
ISR of ABR indicates a trend of subclinical impairments of brain stem function in hyperlipidemic patients, probably due to ischemia accelerated by their condition.
Zhang
Hua
H
Department of Otolaryngology, Fourth Hospital of Hangzhou, Hangzhou 310002.
Wang
Wei
W
D000368:Aged; D002545:Brain Ischemia / Q000175:diagnosis; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged