title: Systemic capillary leak syndrome.
abstract: A 40-year-old woman was referred to our hospital with severe hypovolemic shock and anasarca. The laboratory findings showed marked hemoconcentration and a decrease in total serum protein with the presence of monoclonal IgG-lambda. She had had a similar episode of generalized edema 2 years previously. We diagnosed the patient as having typical systemic capillary leak syndrome (SCLS) and she improved gradually after infusion of albumin-containing fluid. SCLS is a very rare condition caused by unexplained episodic capillary hyperpermeability. Its treatment has remained largely supportive and the prognosis is generally poor. Awareness of SCLS is necessary for improvement of the outcome.
authors.affiliation: Department of Internal Medicine, Nagaoka Red Cross Hospital.
authors.forename: Shotetsu
authors.initials: S
authors.lastname: Kawabe
authors.forename: Takako
authors.initials: T
authors.lastname: Saeki
authors.forename: Hajime
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Masaaki
authors.initials: M
authors.lastname: Nagai
authors.forename: Ryuji
authors.initials: R
authors.lastname: Aoyagi
authors.forename: Shoji
authors.initials: S
authors.lastname: Miyamura
mesh_terms: D000328:Adult; D019559:Capillary Leak Syndrome / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans