title: Randomized clinical trials in melanoma.
abstract: Efforts to improve the survival of patients with metastatic melanoma have led to 67 prospective randomized clinical trials investigating the use of agents comprising three main areas of therapy: systemic chemotherapy-based regimens, immunotherapy, and vaccine therapy
authors.affiliation: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. spanknek@mskcc.org
authors.forename: Kathryn
authors.initials: K
authors.lastname: Spanknebel
authors.forename: Larissa
authors.initials: L
authors.lastname: Temple
authors.forename: Spiros
authors.initials: S
authors.lastname: Hiotis
authors.forename: Alice
authors.initials: A
authors.lastname: Yeh
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Coit
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D008495:Medical Oncology; D008545:Melanoma / Q000556:secondary / Q000628:therapy*; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic