title: Diagnostic techniques for clinical investigation of laboratory zebrafish.
abstract: Unexpected morbidity and mortality of aquatic animal models represent a significant problem for researchers. The authors outline the basic procedures used to diagnose disease outbreaks in laboratory zebrafish colonies, and provide a basic framework for initiating clinical investigations.
authors.affiliation: Division of Comparative Medicine, Massachusetts Institute of Technology, 77 Massachusetts Ave., Building 16-820, Cambridge, MA 02139, USA.
authors.forename: Keith M
authors.initials: KM
authors.lastname: Astrofsky
authors.forename: Claudia M
authors.initials: CM
authors.lastname: Harper
authors.forename: Arlin B
authors.initials: AB
authors.lastname: Rogers
authors.forename: James G
authors.initials: JG
authors.lastname: Fox
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D019411:Clinical Laboratory Techniques / Q000662:veterinary*; D004196:Disease Outbreaks / Q000662:veterinary*; D005393:Fish Diseases / Q000175:diagnosis*; D006652:Histological Techniques; D015027:Zebrafish