[Study on toxicity of P-Dichlorobenzene].
The authors studied the toxicity of P-Dichlorobenzene(P-DCB). The results showed that the toxicity of P-DCB was low. It has no accumulation (K > 5), no eye irritation and no skin sensitization effects. But light skin irritation effect was observed. In sub-acute inhalate exposure, damage on the function of liver and kidney was not observed. Genotoxic tests showed that tests in s. typhimurium strains TA98 and TA100 did not show any mutagenic potential. In Chinese hamster lung fibroblast CHL cell test system, it did not cause chromosomal aberrations.
Yin
X
X
Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021, China.
Qin
Y
Y
Guo
Y
Y
Zhang
L
L
D000818:Animals; D002722:Chlorobenzenes / Q000633:toxicity*; D002869:Chromosome Aberrations; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D006168:Guinea Pigs; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D051379:Mice; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
D002722:Chlorobenzenes; D007306:Insecticides; C018511:4-dichlorobenzene