title: Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity.
abstract: The green tea extract AR25 is an 80% ethanolic dry extract standardized at 25% catechins expressed as epigallocatechin gallate (EGCG). In vitro, green tea extract AR25 exerts a direct inhibition of gastric and pancreatic lipases and a stimulation of thermogenesis. In an open study, the effects of extract AR25 were evaluated in moderately obese patients. After 3 months, body weight was decreased by 4.6% and waist circumference by 4.48%. These results suggest the green tea extract AR25 to be a natural product for the treatment of obesity, which exerts its activity by several ways: inhibition of lipases and stimulation of thermogenesis.
authors.affiliation: Laboratoires Arkopharma, Carros, France. r-d@arkopharma.com
authors.forename: P
authors.initials: P
authors.lastname: Chantre
authors.forename: D
authors.initials: D
authors.lastname: Lairon
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D028241:Camellia sinensis; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D013662:Tea
chemical_list: D010936:Plant Extracts; D013662:Tea; C465546:green tea extract AR25