[Blue-red macules and pseudoatrophic macules in neurofibromatosis 1].
BACKGROUND
Blue-red macules are exception during neurofibromatosis 1. Between October 1988 and March 2000 in our cohort of patients, we systematically looked for these lesions.


METHODS
Presence and number of blue-red macules were evaluated. Biopsies and photographs were proposed to patients.


RESULTS
Forty-four patients out of 583 (39 y; range: 20-66 y) (7.5 p. 100; CI 95 p. 100: 5.5-9.8 p. 100) had blue-red macules mainly on the trunk. Histologically, blue-red macules corresponded to neurofibromatous tissue infiltrating capillary blood vessels and venules.


CONCLUSIONS
Blue-red macules are a peculiar type of neurofibroma and can therefore be considered as a criterion for the diagnosis of neurofibromatosis 1.
Zeller
J
J
Service de Dermatologie, Hôpital Henri-Mondor (AP-HP), Université Paris XII, 94010 Créteil.
Wechsler
J
J
Revuz
J
J
Wolkenstein
P
P
D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000175:diagnosis* / Q000473:pathology; D010781:Photography; D012867:Skin / Q000473:pathology*
Taches violines ou macules pseudo-atrophiques neurofibromateuses au cours de la neurofibromatose 1.