Phenolic glycosides from Phagnalon rupestre.
Analysis of the butanol-soluble fraction from the methanolic extract of the aerial parts of Phagnalon rupestre (Asteraceae) has led to the isolation of seven phenolic compounds. Three have been identified on the basis of their NMR spectra as new natural compounds: the lignan 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyl-tetrahydrofuran-4-O-beta-glucopyranoside (1), the prenylhydroquinone glycoside 1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3'-hydroxy-3'-methylbutyl) benzene (2) and the acetophenone glycoside 12-O-beta-glucopyranosyl-9beta,12-dihydroxytremetone (3). The known flavonoids apigenin-7-O-beta-glucoside, luteolin-7-O-beta-glucoside, luteolin-7-O-beta-glucuronide and the acetophenone picein were also isolated.
Góngora
Luis
L
Departament de Farmacologia, Facultat de Farmàcia, Universitat de València, Avinguda Vicent Andrés Estellés s/n, 46100 Burjassot, València, Spain.
Máñez
Salvador
S
Giner
Rosa M
RM
Carmen Recio
M
M
Gray
Alexander I
AI
Ríos
José Luis
JL
D000098:Acetophenones / Q000737:chemistry*; D019659:Asteraceae / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D017705:Lignans / Q000737:chemistry*; D008968:Molecular Conformation; D018520:Plant Shoots / Q000737:chemistry; D011809:Quinones / Q000737:chemistry*
D000098:Acetophenones; D006027:Glycosides; D017705:Lignans; D011809:Quinones; C038699:acetophenone