title: A short synthesis of (+/-)-epiasarinin.
abstract: [reaction: see text] Epiasarinin, an endo-endo furofuran, has been synthesized from piperonal via a five-step route with good stereocontrol. The sequence involves Darzens condensation, alkenyl epoxide-dihydrofuran rearrangement, and a Lewis acid mediated cyclization.
authors.affiliation: Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, UK.
authors.forename: David J
authors.initials: DJ
authors.lastname: Aldous
authors.forename: Anne J
authors.initials: AJ
authors.lastname: Dalençon
authors.forename: Patrick G
authors.initials: PG
authors.lastname: Steel
mesh_terms: D005663:Furans / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy
chemical_list: D005663:Furans; D007202:Indicators and Reagents; C454643:epiasarinin