title: Secondary metabolites from Centaurea deusta with antimicrobial activity.
abstract: The aerial parts of Centaurea deusta Ten. afforded in addition to several known compounds, mainly sesquiterpene lactones, one new eudesmanolide and one new elemane derivative. Structures of the new compounds were elucidated by spectroscopic methods. The in vitro antifungal and antibacterial activities of the isolated compounds was tested, using the microdilution method. All compounds tested showed high antifungal activity.
authors.affiliation: Department of Pharmacognosy, School of Pharmacy, University of Athens, Panepistimiopolis, Zografou, Greece.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Karioti
authors.forename: Helen
authors.initials: H
authors.lastname: Skaltsa
authors.forename: Diamanto
authors.initials: D
authors.lastname: Lazari
authors.forename: Marina
authors.initials: M
authors.lastname: Sokovic
authors.forename: Begoña
authors.initials: B
authors.lastname: Garcia
authors.forename: Catherine
authors.initials: C
authors.lastname: Harvala
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology; D001230:Aspergillus / Q000187:drug effects; D019659:Asteraceae / Q000378:metabolism*; D007783:Lactones / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D015394:Molecular Structure; D010407:Penicillium / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D007783:Lactones; D012717:Sesquiterpenes