Molecular and cellular biology of Borna disease virus infection.
Borna disease virus (BDV) is a noncytolytic, neurotropic RNA virus that causes neurobehavioral disorders in a wide variety of warm-blooded animals. Recent evidence has revealed that BDV uses a unique strategy in its transcription and replication and directly affects cellular functions of infected central nervous systems. BDV research will provide new insights not only into the biology of neurotropic RNA virus but also into neuropsychiatry.
Tomonaga
Keizo
K
Department of Virology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan. tomonaga@biken.osaka-u.ac.jp
Kobayashi
Takeshi
T
Ikuta
Kazuyoshi
K
D000818:Animals; D001890:Borna Disease / Q000473:pathology / Q000821:virology*; D001891:Borna disease virus / Q000737:chemistry / Q000235:genetics* / Q000502:physiology*; D015967:Gene Expression Regulation, Viral; D016679:Genome, Viral; D011485:Protein Binding; D021381:Protein Transport; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism; D014779:Virus Replication
D014764:Viral Proteins