title: Minimally invasive parathyroid surgery.
abstract: The standard bilateral neck exploration in primary hyperparathyroidism (HPTH) has been challenged in the recent years by the general trend toward less invasive surgery. The development of more reliable preoperative imaging techniques such as Sestamibi scanning and high definition ultrasonography coupled with improvements in intraoperative rapid assays of intact parathyroid hormone have allowed unilateral explorations in most patients with primary HPTH. This article reviews the currently available preoperative parathyroid localization studies as well as the currently used minimally invasive parathyroidectomy (MIP) techniques, such as open approaches, radioguided surgery and endoscopic procedures. While some techniques are more popular than others, careful selection of patients with primary HPTH has resulted in comparable cure rates to the standard bilateral parathyroid exploration.
authors.affiliation: Division of Surgical Oncology and Endocrinology, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA. Sanziana.roman@yale.edu
authors.forename: S
authors.initials: S
authors.lastname: Roman
authors.forename: R
authors.initials: R
authors.lastname: Udelsman
mesh_terms: D015415:Biomarkers / Q000097:blood; D004724:Endoscopy / Q000379:methods; D006801:Humans; D006961:Hyperparathyroidism / Q000601:surgery*; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D010281:Parathyroid Hormone / Q000097:blood; D016105:Parathyroidectomy / Q000379:methods*
chemical_list: D015415:Biomarkers; D010281:Parathyroid Hormone