title: The cardiovascular response to insertion of the intubating laryngeal mask airway.
abstract: Sixty-one patients received a standardised anaesthetic and were randomly assigned to three groups: tracheal intubation via direct laryngoscopy, tracheal intubation via an intubating laryngeal mask airway with immediate removal of the device, and tracheal intubation via an intubating laryngeal mask airway with delayed removal. The cardiovascular response to intubation was of a similar magnitude in all groups, although delayed removal of the intubating laryngeal mask airway was associated with a second pressor response. Norepinephrine changed significantly over time following direct laryngoscopy and following immediate removal of the intubating laryngeal mask airway, but not after delayed removal. The findings of this study do not support using the intubating laryngeal mask instead of direct laryngoscopy purely to decrease the response to intubation.
authors.affiliation: Anaesthetic Department, Kings College Hospital, London SE5 9RS, UK.
authors.forename: A
authors.initials: A
authors.lastname: Choyce
authors.forename: M S
authors.initials: MS
authors.lastname: Avidan
authors.forename: A
authors.initials: A
authors.lastname: Harvey
authors.forename: C
authors.initials: C
authors.lastname: Patel
authors.forename: C
authors.initials: C
authors.lastname: Timberlake
authors.forename: K
authors.initials: K
authors.lastname: Sarang
authors.forename: L
authors.initials: L
authors.lastname: Tilbrook
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D001794:Blood Pressure; D020878:Device Removal; D004837:Epinephrine / Q000097:blood; D005260:Female; D006339:Heart Rate; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods; D017214:Laryngeal Masks; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D011446:Prospective Studies; D016037:Single-Blind Method; D013997:Time Factors
chemical_list: D009638:Norepinephrine; D004837:Epinephrine