[Peripheral retinal neovascularization and sarcoidosis: two case reports].
Peripheral retinal neovascularization occurs in approximately 10% of cases of sarcoidosis. Its pathogenesis is unknown, but it probably results from retinal ischemia and/or inflammation. In cases of peripheral retinal neovascularization associated with sarcoidosis, sickle cell disease should be considered, even if sarcoidosis is histologically proved: new vessels seen in sickle cell disease and sarcoidosis may have a very similar pattern. We present two cases with histologically proven sarcoidosis who developed peripheral neovascularization: the first one had no associated disease and new vessels were likely to be related to sarcoidosis; in the second case, hemoglobin electrophoresis revealed hemoglobin SC, and provided diagnosis of sickle cell hemoglobinopathy.
Girmens
J F
JF
Service d'ophtalmologie, Hôpital Avicenne, 125 avenue de Stalingrad, 93009 Bobigny Cedex.
Fajnkuchen
F
F
Badelon
I
I
Chaine
G
G
D000328:Adult; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006450:Hemoglobin SC Disease / Q000150:complications; D006801:Humans; D017075:Laser Coagulation; D008206:Lymphatic Diseases / Q000150:complications*; D008297:Male; D015861:Retinal Neovascularization / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D012507:Sarcoidosis / Q000150:complications*; D017565:Sarcoidosis, Pulmonary / Q000150:complications*; D012871:Skin Diseases / Q000150:complications*; D013997:Time Factors; D014792:Visual Acuity
Néovascularisation périphérique et sarcoïdose.