title: Retention of configuration on the oxidative addition of P-H bond to platinum (0) complexes: the first straightforward synthesis of enantiomerically pure P-chiral alkenylphosphinates via palladium-catalyzed stereospecific hydrophosphinylation of alkynes.
abstract: The oxidative addition of pure (R(P))-menthyl phenylphosphinate 1 to a platinum (0) complex proceeds readily with retention of configuration at the chiral phosphorus center which was unambiguously confirmed by an X-ray analysis. In the presence of a catalytic amount of palladium, the hydrophosphinylation of a variety of alkynes with 1 also takes place stereospecifically, with retention of configuration, affording high yields of the corresponding vinylphosphinates bearing a single chirality at phosphorus.
authors.affiliation: National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 5, Tsukuba, Ibaraki 305-8565, Japan. libiao-han@aist.go.jp
authors.forename: Li-Biao
authors.initials: LB
authors.lastname: Han
authors.forename: Chang-Qiu
authors.initials: CQ
authors.lastname: Zhao
authors.forename: Shun-ya
authors.initials: SY
authors.lastname: Onozawa Sy
authors.forename: Midori
authors.initials: M
authors.lastname: Goto
authors.forename: Masato
authors.initials: M
authors.lastname: Tanaka
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry; D008968:Molecular Conformation; D009944:Organoplatinum Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D010721:Phosphinic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D009944:Organoplatinum Compounds; D010721:Phosphinic Acids; D010165:Palladium; D006859:Hydrogen