[Clinical and experimental study on treatment of acute catarrhal otitis media with eryanling oral liquid].
OBJECTIVE
To study the clinical effect and mechanism of Eryanling (EYL) oral liquid in treating acute catarrhal otitis media (ACOM).


METHODS
Sixty-eight cases (89 ears) of ACOM in the treated group were treated with EYL and compared with 34 cases (44 ears) in the control group treated with cephalexinum. Experimental study of effect of EYL on immune function in mice and non-suppurative otitis guinea pig was also conducted.


RESULTS
The total effective rate of the treated group and the control group was 91.0% and 84.1% respectively, and their rate of curing 80.9% and 70.5% respectively, though the effect in the former was better, statistic analysis showed no significance between them. The effect initiated obviously earlier in the treated group than that in the control group. Results of experimental study suggested that EYL could strengthen the nonspecific immune function, cellular immune function and humoral immune function in mice, and reduce the degree of inflammatory exudation and mucosa swollen in guinea pig.


CONCLUSIONS
EYL has good therapeutic effect in treating ACOM.
Zhang
H
H
Xiyuan Hospital, China Academy of TCM, Beijing 100091.
Li
S
S
Liu
R
R
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D051379:Mice; D008875:Middle Aged; D010034:Otitis Media with Effusion / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D008517:Phytotherapy; D014432:Tympanic Membrane / Q000473:pathology
D004365:Drugs, Chinese Herbal