title: Traumatic hypopituitarism due to maternal uterine leiomyomas.
abstract: Hypopituitarism has been associated with different types of head trauma including traumatic delivery. We report a case of hypopituitarism in a boy with a history of induced traumatic labor associated with maternal uterine leiomyomas. He also had head and face deformations that were apparently caused by spatial restriction due to the enlarging leiomyomas while the patient was growing in utero. Trauma to the pituitary stalk could have occurred by cerebral entrapment and the pressures of labor. Although hypopituitarism has been associated with traumatic delivery and breech delivery, there are no reported cases related to uterine leiomyomas.
authors.affiliation: Division of Pediatric Endocrinology, Metabolism and Nutrition, Mayo Clinic, Rochester, MN 55905, USA. minutti.carla@mayo.edu
authors.forename: C Z
authors.initials: CZ
authors.lastname: Minutti
authors.forename: D
authors.initials: D
authors.lastname: Zimmerman
mesh_terms: D001720:Birth Injuries / Q000473:pathology; D019465:Craniofacial Abnormalities / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D007231:Infant, Newborn; D007889:Leiomyoma / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D007744:Obstetric Labor Complications; D010902:Pituitary Gland / Q000293:injuries / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D014594:Uterine Neoplasms / Q000150:complications*