title: [Clinical significance of serum levels of medium size molecules in patients with iron deficiency anemia].
abstract: Overall 45 patients (20 men and 25 women) with iron deficiency anemia (IDA) were examined. The content was measured of medium-size molecules (MSM) in the blood serum of patients with different degree IDA. The time-related course was followed of changes in MSM content during the course of treatment of the patients. The control group comprised 22 essentially healthy subjects. The blood serum content of MSM in IDA patients proved to be significantly higher as compared to healthy individuals (P < 0.001). Recordable in the patients was a significant IDA severity-related increase in MSM content. Clinical, diagnostic, and prognostic significance of MSM content in IDA patients is discussed. It is suggested that the foregoing biochemical criterion be used in a comprehensive assessment of degree of severity of the endogenous metabolic intoxication in patients with IDA.
authors.forename: S V
authors.initials: SV
authors.lastname: Vydyborets'
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000097:blood*; D005260:Female; D006801:Humans; D046911:Macromolecular Substances; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight; D010455:Peptides / Q000097:blood*; D012720:Severity of Illness Index
chemical_list: D046911:Macromolecular Substances; D010455:Peptides
vernacular_title: Klinichne znachennia vmistu molekul seredn'oï masy u syrovattsi krovi khvorykh iz zalizodefitsytnoiu anemiieiu.