title: [The effects of BDP on calcium ion in the granular leukocytes in nasal secretions of the patients with allergic rhinitis].
abstract: OBJECTIVE
  To study the effects of beclomethasone dipropionate (BDP) on the inflammatory granular leukocytes in nasal secretions of the patients with allergic rhinitis.
  
  
  METHODS
  The change of intercellular calcium ion of the eosinophils and neutrophils in the nasal secretions were observed under the laser scanning confocal microscopy and technology of fluorescence.
  
  
  RESULTS
  The concentration of intercellular calcium ion either in eosinophils or in neutrophils significantly rose after BDP treatment.
  
  
  CONCLUSIONS
  BDP can rise the concentration of intercellular calcium ion in the granular leukocytes, which may be a factor of the anti-inflammation functions of BDP.
authors.affiliation: Department of Otolaryngology, First Affiliated Hospital of Shantou University Medical College, Shantou 515041.
authors.forename: Zhizhong
authors.initials: Z
authors.lastname: Shen
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.forename: Huige
authors.initials: H
authors.lastname: Wang
authors.forename: Juelong
authors.initials: J
authors.lastname: Lin
authors.forename: Yaowen
authors.initials: Y
authors.lastname: Chen
authors.forename: Dehui
authors.initials: D
authors.lastname: Song
mesh_terms: D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001507:Beclomethasone / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D002478:Cells, Cultured; D004804:Eosinophils / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D009297:Nasal Mucosa / Q000378:metabolism*; D009504:Neutrophils / Q000187:drug effects* / Q000378:metabolism; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D001507:Beclomethasone; D002118:Calcium