[Biomechanical study on the composite of allogenic decalcified bone matrix gelatin and bone cement].
OBJECTIVE
To evaluate the biomechanical properties and structural characteristics of various composites of partially decalcified allogenic bone matrix gelatin and bone cement at different ratios.


METHODS
According to Urist method, partially decalcified allogenic bone matrix gelatin was prepared and mixed with bone cement at different ratios of 0, 400, 500, and 600 mg/g. Then the comparisons of these composites were performed in microstructure, ultimate compression strength and ultimate bending strength properties.


RESULTS
The electronic microscope showed that the bone particles and bone cement were distributed evenly in the composite, irregularly connecting by multiple points; with the increase of bone particles and decrease of bone cement in the composite, there were more and more natural crevices, varying from 100 microns to 400 microns in width, in the biomaterials. Of all the composites with the ratios of 0, 400, 500, and 600 mg/g, the measurements of ultimate compression strength were (71.7 +/- 2.0) MPa, (46.9 +/- 3.3) MPa, (39.8 +/- 4.1) MPa, and (32.2 +/- 3.4) MPa, respectively; and the measurements of ultimate bending strength were (65.0 +/- 3.4) MPa, (38.2 +/- 4.0) MPa, (33.1 +/- 4.3) MPa and (25.3 +/- 4.6) MPa, respectively.


CONCLUSIONS
The composite of partially decalcified allogenic bone matrix gelatin and bone cement has a good biomechanical property and could be easily fabricated and re-shaped, which make it available to be used clinically as an idea bone graft biomaterial.
Hu
Yun-Sheng
YS
Orthopedic Oncology Institute of People's Liberation Army, Tangdu Hospital, Forth Military Medical University, Xi'an, Shaanxi, P. R. China, 710038.
Fan
Qing-Yu
QY
Zhou
Yong
Y
Liu
Gao-Jie
GJ
Zhang
Dian-Zhong
DZ
D001696:Biomechanical Phenomena; D001843:Bone Cements; D018786:Bone Substitutes; D019245:Compressive Strength; D003648:Decalcification Technique; D005780:Gelatin
D001843:Bone Cements; D018786:Bone Substitutes; D005780:Gelatin