title: Hypertensive pontine microhemorrhage.
abstract: OBJECTIVE
  This study investigated whether the topography of hypertensive pontine microhemorrhages (hPMHs) resembles that of larger primary pontine hemorrhages.
  
  
  METHODS
  Sixty-nine consecutive patients with small-vessel disease underwent imaging with gradient-echo MRI, and 27 patients with hPMH were detected. Lesion size and location along the rostrocaudal (longitudinal), lateral (coronal), and anteroposterior (sagittal) axes were determined.
  
  
  RESULTS
  A total of 52 hPMHs were identified in the 27 patients (mean, 1.93+/-2.4 per patient). The lesions showed a nonrandom distribution, with a propensity to occur in the middle pons in the rostrocaudal axis, posterior half of the basis pontis in the anteroposterior axis, and central subdivision within the lateral axis. The area of hPMH ranged from 1.3 to 19.0 mm2 (mean, 5.06+/-3.72 mm2). The size of hPMH did not vary as a function of lesion location.
  
  
  CONCLUSIONS
  Previous studies reported that primary pontine hemorrhages tend to occur in the middle pons and at the junction of basis pontis and tegmentum. Therefore, topographical correspondences between large and small pontine hemorrhages may provide evidence that the 2 lesions share some etiological basis. Further investigation may determine whether hPMHs portend future symptomatic primary pontine hemorrhages.
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Jee-Hyang
authors.initials: JH
authors.lastname: Jeong
authors.forename: Soo Jin
authors.initials: SJ
authors.lastname: Yoon
authors.forename: Sue J
authors.initials: SJ
authors.lastname: Kang
authors.forename: Kyung Gyu
authors.initials: KG
authors.lastname: Choi
authors.forename: Duk L
authors.initials: DL
authors.lastname: Na
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D015140:Dementia, Vascular / Q000150:complications / Q000175:diagnosis*; D003710:Demography; D017352:Echo-Planar Imaging; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis*; D020300:Intracranial Hemorrhages / Q000145:classification / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D008833:Microcirculation / Q000473:pathology; D008875:Middle Aged; D009483:Neuropsychological Tests; D011149:Pons / Q000098:blood supply* / Q000473:pathology; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index