title: [Biomechanical study on the composite of allogenic decalcified bone matrix gelatin and bone cement].
abstract: OBJECTIVE
  To evaluate the biomechanical properties and structural characteristics of various composites of partially decalcified allogenic bone matrix gelatin and bone cement at different ratios.
  
  
  METHODS
  According to Urist method, partially decalcified allogenic bone matrix gelatin was prepared and mixed with bone cement at different ratios of 0, 400, 500, and 600 mg/g. Then the comparisons of these composites were performed in microstructure, ultimate compression strength and ultimate bending strength properties.
  
  
  RESULTS
  The electronic microscope showed that the bone particles and bone cement were distributed evenly in the composite, irregularly connecting by multiple points; with the increase of bone particles and decrease of bone cement in the composite, there were more and more natural crevices, varying from 100 microns to 400 microns in width, in the biomaterials. Of all the composites with the ratios of 0, 400, 500, and 600 mg/g, the measurements of ultimate compression strength were (71.7 +/- 2.0) MPa, (46.9 +/- 3.3) MPa, (39.8 +/- 4.1) MPa, and (32.2 +/- 3.4) MPa, respectively; and the measurements of ultimate bending strength were (65.0 +/- 3.4) MPa, (38.2 +/- 4.0) MPa, (33.1 +/- 4.3) MPa and (25.3 +/- 4.6) MPa, respectively.
  
  
  CONCLUSIONS
  The composite of partially decalcified allogenic bone matrix gelatin and bone cement has a good biomechanical property and could be easily fabricated and re-shaped, which make it available to be used clinically as an idea bone graft biomaterial.
authors.affiliation: Orthopedic Oncology Institute of People's Liberation Army, Tangdu Hospital, Forth Military Medical University, Xi'an, Shaanxi, P. R. China, 710038.
authors.forename: Yun-Sheng
authors.initials: YS
authors.lastname: Hu
authors.forename: Qing-Yu
authors.initials: QY
authors.lastname: Fan
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.forename: Gao-Jie
authors.initials: GJ
authors.lastname: Liu
authors.forename: Dian-Zhong
authors.initials: DZ
authors.lastname: Zhang
mesh_terms: D001696:Biomechanical Phenomena; D001843:Bone Cements; D018786:Bone Substitutes; D019245:Compressive Strength; D003648:Decalcification Technique; D005780:Gelatin
chemical_list: D001843:Bone Cements; D018786:Bone Substitutes; D005780:Gelatin