title: Chemotaxonomic features associated with flavonoids of cannabinoid-free cannabis (Cannabis sativa subsp. sativa L.) in relation to hops (Humulus lupulus L.).
abstract: The major flavonoids present in the leaves and flowers of the cannabinoid-free cannabis (Cannabis sativa subsp. sativa L.) cultivars Felina and Futura are orientin (1), vitexin (2), luteolin-7-O-beta-D-glucuronide (3), and apigenin-7-O-beta-D-glucuronide (4), while prenylated flavonoids, to which the potent estrogenicity of hops (Humilus lupulus L.) is associated, are absent. The different composition of flavonoids has chemotaxonomic value.
authors.affiliation: Ghent University, Faculty of Pharmaceutical Sciences, Laboratory of Pharmacognosy and Phytochemistry, Belgium.
authors.forename: Gerd
authors.initials: G
authors.lastname: Vanhoenacker
authors.forename: Philippe
authors.initials: P
authors.lastname: Van Rompaey
authors.forename: Denis
authors.initials: D
authors.lastname: De Keukeleire
authors.forename: Pat
authors.initials: P
authors.lastname: Sandra
mesh_terms: D047310:Apigenin; D002188:Cannabis / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004967:Estrogens / Q000378:metabolism; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry; D005966:Glucuronidase / Q000378:metabolism; D006801:Humans; D027582:Humulus / Q000737:chemistry*; D006868:Hydrolysis; D047311:Luteolin; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011960:Receptors, Estrogen / Q000187:drug effects; D012441:Saccharomyces cerevisiae; D021241:Spectrometry, Mass, Electrospray Ionization; D001617:beta-Glucosidase / Q000378:metabolism
chemical_list: D004967:Estrogens; D005419:Flavonoids; D005960:Glucosides; D011960:Receptors, Estrogen; C456097:apigenin-7-O-glucuronide; C456096:luteolin-7-O-glucuronide; D047310:Apigenin; C032731:vitexin; D001617:beta-Glucosidase; D005966:Glucuronidase; C065886:orientin; D047311:Luteolin