title: Combined corneal lipid and calcium degeneration in a dog with hyperadrenocorticism: a case report.
abstract: Corneal degeneration may occur with a deposition of lipids or calcium, or both. Calcareous and lipid degeneration may be either primary or secondary, associated with systemic diseases such as primary hyperlipidemia, hyperlipidemia associated with hyperadrenocorticism, and hypothyroidism. The authors report a case of bilateral corneal lipid and calcium degeneration in a 7-year-old female Poodle with hyperadrenocorticism. The condition worsened with Lysodren therapy but responded to surgical excision.
authors.affiliation: Veterinary College, São Paulo State University, UNESP, Jaboticabal, SP, Brazil. jllaus@fcav.unesp.br
authors.forename: José L
authors.initials: JL
authors.lastname: Laus
authors.forename: Cristiane
authors.initials: C
authors.lastname: dos Santos
authors.forename: Ivia C
authors.initials: IC
authors.lastname: Talieri
authors.forename: Arianne P
authors.initials: AP
authors.lastname: Oriá
authors.forename: Gervásio H
authors.initials: GH
authors.lastname: Bechara
mesh_terms: D000308:Adrenocortical Hyperfunction / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D002114:Calcinosis / Q000662:veterinary; D003316:Corneal Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D005260:Female; D008064:Lipidoses / Q000662:veterinary; D008939:Mitotane / Q000627:therapeutic use
chemical_list: D018931:Antineoplastic Agents, Hormonal; D008939:Mitotane