title: [Effect of zinc on the cellular immunity and NK cell activity in acute heat exposed rats].
abstract: To study the effects of zinc on the cellular immunity and NK cell activity in acute heat-exposed rats. Rats were fed with dietary containing high, moderate and low zinc for 15 days. The concentrations of zinc in high, moderate and low zinc dietary are 92.20 mg/kg, 45.61 mg/kg and 21.70 mg/kg respectively. After exposed to acute heat (41.5 degrees C) for 5 min, 30 min and 60 min, the rats were killed and the cellular immunity and NK cell activity were measured. The proliferation of lymphocyte and the NK cell activity were higher in high zinc group than in moderate and low zinc groups no matter the rats were exposed to heat or not. Zinc can improve the cellular immunity and NK cell activity in acute heat exposed rats.
authors.affiliation: Faculty of Medical Service, Second Military Medical University, Shanghai 200433, China.
authors.forename: H
authors.initials: H
authors.lastname: Xu
authors.forename: F
authors.initials: F
authors.lastname: Zhao
authors.forename: J
authors.initials: J
authors.lastname: Guo
authors.forename: C
authors.initials: C
authors.lastname: Ling
mesh_terms: D000818:Animals; D018882:Heat Stress Disorders / Q000276:immunology*; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000276:immunology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D015032:Zinc / Q000494:pharmacology*
chemical_list: D015032:Zinc