title: Effects of deltamethrin on lipid peroxidation in mice.
abstract: Effects of deltamethrin on lipid peroxidation were investigated for subacute, subchronic and chronic periods. Deltamethrin was given to Swiss Albino mice at 1.5, 2.5, or 7.5 mg/kg. Lipid peroxidation was evaluated by determining malondialdehyde (MDA) levels in plasma, and determining glutathione peroxidase (GSH-Px), superoxide dismutase (Cu-Zn SOD) and catalase activities in erythrocytes on days 15, 45, and 60. MDA levels increased in deltamethrin dosed groups, especially for the subchronic and chronic periods. GSH-Px, Cu-Zn SOD and catalase activities in erythrocytes were decreased at high doses of deltamethrin, especially at the high dose (7.5 mg/kg) deltamethrin group.
authors.affiliation: Ankara University, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Diskapi, Turkey.
authors.forename: Ender
authors.initials: E
authors.lastname: Yarsan
authors.forename: Ali
authors.initials: A
authors.lastname: Bilgili
authors.forename: Murat
authors.initials: M
authors.lastname: Kanbur
authors.forename: Sefa
authors.initials: S
authors.lastname: Celik
mesh_terms: D000818:Animals; D002374:Catalase / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000201:enzymology; D005979:Glutathione Peroxidase / Q000494:pharmacology; D007306:Insecticides / Q000009:adverse effects*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008315:Malondialdehyde / Q000097:blood; D051379:Mice; D009570:Nitriles; D011722:Pyrethrins / Q000009:adverse effects*; D013482:Superoxide Dismutase / Q000494:pharmacology
chemical_list: D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin; D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase