title: Fractal analysis in the detection of colonic cancer images.
abstract: The aim of this study was to investigate the value of fractal dimension in separating normal and cancerous images, and to examine the relationship between fractal dimension and traditional texture analysis features. Forty-four normal images and 58 cancer images from sections of the colon were analyzed. A "leave-one-out" analysis approach was used to classify the samples into each group. With fractal analysis there was a highly significant difference between groups (p < 0.0001). Correlation and entropy features showed greater differences between the groups (p < 0.0001). Nevertheless, the addition of fractal analysis to the feature analysis improved the sensitivity from 90% to 95% and specificity from 86% to 93%.
authors.affiliation: Department of Electrical and Electronic Engineering, University of Newcastle, Newcastle upon Tyne, UK.
authors.forename: Abdelrahim Nasser
authors.initials: AN
authors.lastname: Esgiar
authors.forename: Raouf N G
authors.initials: RN
authors.lastname: Naguib
authors.forename: Bayan S
authors.initials: BS
authors.lastname: Sharif
authors.forename: Mark K
authors.initials: MK
authors.lastname: Bennett
authors.forename: Alan
authors.initials: A
authors.lastname: Murray
mesh_terms: D016022:Case-Control Studies; D003110:Colonic Neoplasms / Q000473:pathology*; D017709:Fractals; D006801:Humans