[Intracranial artery occlusive diseases in patients with hypertension and diabetes mellitus].
OBJECTIVE
To investigate risk effects of hypertension (HT) and diabetes mellitus (DM) to intracranial artery occlusive lesions.


METHODS
845 patients (South group) visiting the First Affiliated Hospital of Zhejiang University, and 2325 patients (North group) visiting the Peking Union Medical College Hospital were assessed respeitively. All the patients underwent transcranial Doppler detection to discover intracranial occlusive artery lesions. Age, sex, hypertension (HT) and diabetes mellitus (DM) were included in the analysis.


RESULTS
Among the patients > or = 50 years old, the frequencies of middle cerebral artery(MCA) occlusive diseases were: 6.96%, 11.43%, 20.59% and 1.75% in South; 6.24%, 11.18%, 13.51% and 1.95% in North, when suffering from HT, DM, both of HT and DM(MIX), or neither of them(Nor). The risk ratios of HT, DM, MIX were: 4.0, 6.5 and 11.8 in South; 3.2, 5.7 and 6.9 in North; and 2.9, 16.9 and 37.3 when combining South and North. There were no statistical differences of frequencies of MCA occlusive lesions under HT, DM and MIX between the South and North. Multi-variable logistic regression analysis showed that HT and DM were significant and independent predictors for MCA occlusive lesion. The details of other cerebral arteries were canceled here.


CONCLUSIONS
Hypertension and diabetes mellitus may contribute to the development of occlusive lesions of the cerebral arteries in Chinese people.
Liu
Y
Y
Department of Neurology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China.
Huang
Y
Y
Wang
B
B
D000328:Adult; D000367:Age Factors; D000368:Aged; D002536:Cerebral Arteries / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology; D002681:China / Q000453:epidemiology; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D012737:Sex Factors; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods