title: Long-term impact of treatment in women diagnosed with bulimia nervosa.
abstract: OBJECTIVE
  Both cognitive-behavioral therapy (CBT) and antidepressant medication have demonstrated efficacy in the treatment of bulimia nervosa. However, data concerning the long-term impact of such treatments have been limited. This study sought to determine if treatment with CBT and antidepressant medication was associated with better long-term outcome among women diagnosed with bulimia nervosa.
  
  
  METHODS
  Women (N = 101) who completed a controlled treatment study of bulimia nervosa participated in follow-up assessments approximately 10 years later.
  
  
  RESULTS
  Women who received treatment with CBT or antidepressant medication or both reported improved social adjustment at long-term follow-up compared with women randomized to the placebo condition.
  
  
  CONCLUSIONS
  Treatments with demonstrated efficacy for short-term outcome appear to improve psychosocial function at long-term follow-up among women initially diagnosed with bulimia nervosa.
authors.affiliation: Department of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA. pkeel@wjh.harvard.edu
authors.forename: Pamela K
authors.initials: PK
authors.lastname: Keel
authors.forename: James E
authors.initials: JE
authors.lastname: Mitchell
authors.forename: Traci L
authors.initials: TL
authors.lastname: Davis
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Crow
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D002032:Bulimia / Q000523:psychology / Q000628:therapy*; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use*; D012917:Social Adjustment; D013997:Time Factors
chemical_list: D000929:Antidepressive Agents, Tricyclic; D007099:Imipramine