title: Landau-Kleffner syndrome (acquired epileptic aphasia) in a Nigerian child.
abstract: Epilepsy is one of the commonest disorders presenting the neurological clinics in developing countries. There are attendant complications especially in untreated or poorly treated cases. In this article, we report an uncommon complication known as Landau-Kleffner syndrome in a Nigerian girl. The syndrome, typically seen in children consists of an acquired aphasia frequently associated with clinical seizures and paroxysmal electroencephalographic (EEG) accompaniment. There had been no adequate neuropathlogical correlations to explain the symptomatology; thus, various forms of pathogenesis have been ascribed to the syndrome. The clinical seizure is easily controlled by an antiepileptic; but speech recovery is variable, and this is usually poor in cases presenting one or two years after onset.
authors.affiliation: Department of Psychiatry, College of Medicine, University of Lagos, P.M.B. 12003, Lagos, Nigeria.
authors.forename: O F
authors.initials: OF
authors.lastname: Aina
authors.forename: O
authors.initials: O
authors.lastname: Morakinyo
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D002675:Child, Preschool; D002746:Chlorpromazine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D005260:Female; D006801:Humans; D018887:Landau-Kleffner Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D009549:Nigeria
chemical_list: D000927:Anticonvulsants; D014150:Antipsychotic Agents; D002220:Carbamazepine; D002746:Chlorpromazine