[Deiodinase].
The members of deiodinase family including type I, type II and type III deiodinase are seleno-proteins. They play an important role in the regulation of thyroid hormone metabolism. They are different in substrate specificity and sensitivity to inhibitor and kinetics mechanism. Their cDNAs exhibit limited regions of homology, but they have common conserved sequence, TGA codon of selenocysteine and some structures and sequences which are essential for selenocysteine insertion.
Zhang
Z
Z
Institute of Nutrition & Food Hygiene, Chinese Academy of Preventive Medicine, Beijing 100050, China.
Yang
X
X
Xia
Y
Y
Chen
X
X
D000818:Animals; D006801:Humans; D007453:Iodide Peroxidase / Q000235:genetics / Q000502:physiology*
D007453:Iodide Peroxidase