title: [Studies on synthesis and bioactivity of 2-alkenyl-4(1H)-quinolone].
abstract: Three 2-alkenyl-4(1H)-quinolone compounds(I-III) were synthesized by two methods. III is a new compound from Evodia rutaecarpa and was synthesized through the reaction of the aldehyde intermediate(5) with Wittig reagent. The other two compounds were synthesized for the first time. These compounds showed vasodilating and antibacteria effects in pharmacological tests.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050.
authors.forename: Y
authors.initials: Y
authors.lastname: Tang
authors.forename: K
authors.initials: K
authors.lastname: Wu
authors.forename: X
authors.initials: X
authors.lastname: Feng
authors.forename: L
authors.initials: L
authors.lastname: Huang
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000897:Anti-Ulcer Agents / Q000138:chemical synthesis / Q000494:pharmacology; D015363:Quinolones / Q000138:chemical synthesis* / Q000494:pharmacology; D027821:Rutaceae / Q000737:chemistry; D014665:Vasodilator Agents / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D000897:Anti-Ulcer Agents; D015363:Quinolones; D014665:Vasodilator Agents