title: Central anticholinergic syndrome in a child undergoing circumcision.
abstract: We describe one of the few pediatric cases of central anticholinergic syndrome (CAS) in an 8-year-old boy undergoing elective surgery. Deep sedation, inadequate response to stimuli and reduced muscular tone of the upper airway resulting in airway obstruction were the clinical manifestations of CAS. The symptoms resolved immediately after administration of physostigmine. This case illustrates the importance of considering central anticholinergic syndrome as a differential diagnosis in children if prolonged sedation after general anesthesia occurs.
authors.affiliation: Klinik für Anästhesiologie, Universitätsklinikum der RWTH, Aachen, Germany. uta.schultz@post.rwth-aachen.de
authors.forename: U
authors.initials: U
authors.lastname: Schultz
authors.forename: R
authors.initials: R
authors.lastname: Idelberger
authors.forename: R
authors.initials: R
authors.lastname: Rossaint
authors.forename: W
authors.initials: W
authors.lastname: Buhre
mesh_terms: D000758:Anesthesia / Q000009:adverse effects*; D002493:Central Nervous System Diseases / Q000139:chemically induced*; D002648:Child; D002944:Circumcision, Male / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010276:Parasympatholytics / Q000009:adverse effects*; D010830:Physostigmine / Q000627:therapeutic use; D013577:Syndrome
chemical_list: D010276:Parasympatholytics; D010830:Physostigmine