Trisomy 4 as the sole cytogenetic abnormality in a Waldenström macroglobulinemia.
We report a case of Waldenström macroglobulinemia with trisomy 4 as the sole cytogenetic abnormality. Trisomy 4 has been reported previously in Waldenström macroglobulinemia, but only in conjunction with multiple chromosomal aberrations. Trisomy 4 has been reported in other hematologic malignancies including acute myeloid and lymphoid leukemias.
Rivera
Ada I
AI
Department of Pathology and Laboratory Medicine, Tulane Health Sciences Center, New Orleans, LA 70131, USA.
Li
Marilyn M
MM
Beltran
German
G
Krause
John R
JR
D000368:Aged; D015703:Antigens, CD / Q000378:metabolism; D001772:Blood Cell Count; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations; D002894:Chromosomes, Human, Pair 4 / Q000235:genetics*; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D014314:Trisomy / Q000235:genetics*; D008258:Waldenstrom Macroglobulinemia / Q000235:genetics* / Q000473:pathology
D015703:Antigens, CD