title: Management of tuberculosis in a British inner-city population.
abstract: BACKGROUND
  The aim of the study was to investigate the management of patients with tuberculosis (TB) in terms of their utilization of health service resources.
  
  
  METHODS
  An analysis of patient records was carried out in an NHS Trust in East London, United Kingdom, serving a socioeconomically deprived population. The subjects were all residents of Tower Hamlets treated for drug-sensitive TB in the in-patient and out-patient departments of the Trust in 1998.
  
  
  RESULTS
  Of the 62 patients with TB studied, 38 (61 per cent) had an in-patient stay at some stage of their management. Twenty-six of these 38 were admitted acutely ill via the Accident and Emergency Department, 16 having self-presented and 10 after urgent referral by their general practitioner. Only four of the total 62 patients were admitted with previously diagnosed disease, and all four had significant complications necessitating admission. Eight patients were admitted electively for investigation, typically being brief admissions for surgical biopsy. Median in-patient stay was 14 days (range 1-144 days), and in six cases we identified potentially remediable delays in diagnosis and initiation of therapy.
  
  
  CONCLUSIONS
  UK and US guidelines for TB imply out-patient management as the norm. Our study shows a very high rate of in-patient care, largely a consequence of the emergency admission of acutely ill, previously undiagnosed cases. There are public health implications in terms of spread of infection from individuals with advanced disease. The high utilization of expensive in-patient resources has significant implications for purchasers and providers of care for TB in socio-economically deprived areas. Further, the cost-effectiveness of public health interventions aimed at limiting the spread of TB should be assessed by reference to this true, high cost of managing TB, not a low cost based on false assumptions about rates of out-patient versus in-patient care.
authors.affiliation: Department of Respiratory Medicine, Bart's and The London Trust. vlcw@btinternet.com
authors.forename: Veronica L C
authors.initials: VL
authors.lastname: White
authors.forename: Mehjabeen
authors.initials: M
authors.lastname: Paliwalla
authors.forename: Claire J
authors.initials: CJ
authors.lastname: Steves
authors.forename: Deepa
authors.initials: D
authors.lastname: Jadhav
authors.forename: John
authors.initials: J
authors.lastname: Moore-Gillon
mesh_terms: D002391:Catchment Area, Health; D017281:Cost of Illness; D005006:Ethnicity; D006302:Health Services Research; D006760:Hospitalization / Q000706:statistics & numerical data*; D006779:Hospitals, Public / Q000706:statistics & numerical data*; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008131:London / Q000453:epidemiology; D010346:Patient Care Management; D011204:Poverty Areas; D012720:Severity of Illness Index; D013222:State Medicine; D014376:Tuberculosis / Q000191:economics / Q000453:epidemiology* / Q000517:prevention & control / Q000628:therapy*; D019037:Urban Health Services / Q000458:organization & administration / Q000706:statistics & numerical data*; D014600:Utilization Review