Electric current density imaging of tablet dissolution.
The Electric current density imaging technique (CDI) was used to monitor the dissolution of and ion migration from tablets of different acids in agar-agar gel. Conventional MRI cannot monitor these processes, since it can only show changes in the size of the tablet during the dissolving process. CDI traces the dissolved ions thanks to changes in conductivity.
Mikac
Ursa
U
Jozef Stefan Institute, Jamova 39, Ljubljana, Slovenia.
Demsar
Alojz
A
Sersa
Igor
I
Demsar
Franci
F
D004560:Electricity; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012995:Solubility; D012996:Solutions / Q000032:analysis / Q000737:chemistry; D013607:Tablets / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D013997:Time Factors
D012996:Solutions; D013607:Tablets