Distribution of tissue kallikrein in the integumental blood vessel system of wild mammals.
The study demonstrates tissue kallikrein with the help of a very sensitive immunohistochemical B-SA method in smooth muscle cells and myocytes / pericytes of the wall of subepidermal arterioles and capillaries of 17 mammalian species from 6 different orders. Positive immunoreactions could also be detected in the wall of blood vessels near to and between hair follicles and skin glands. The reaction staining in subepidermal blood vessels was particularly distinct in animals with a vital epidermis that was significantly thicker than 20 microm. The results obtained are discussed with special regard to the general skin biology of the wild mammals studied, considering comparative hair coat density and normal hazards to the integument.
Meyer
W
W
Anatomisches Institut, Tierärztliche Hochschule Hannover, Germany. wilfried.meyer@tiho-hannover.de
D000818:Animals; D000835:Animals, Wild; D001808:Blood Vessels / Q000201:enzymology*; D005260:Female; D018859:Hair Follicle / Q000098:blood supply; D007150:Immunohistochemistry; D008297:Male; D008322:Mammals / Q000378:metabolism*; D012867:Skin / Q000098:blood supply; D014018:Tissue Distribution; D020840:Tissue Kallikreins / Q000378:metabolism*
D020840:Tissue Kallikreins