title: New anti-HSV therapeutics target the helicase-primase complex.
authors.forename: Clyde S
authors.initials: CS
authors.lastname: Crumpacker
authors.forename: Priscilla A
authors.initials: PA
authors.lastname: Schaffer
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D004265:DNA Helicases / Q000037:antagonists & inhibitors*; D019915:DNA Primase; D004261:DNA Replication / Q000187:drug effects; D004279:DNA, Viral / Q000096:biosynthesis; D006561:Herpes Simplex / Q000188:drug therapy*; D006801:Humans; D046911:Macromolecular Substances; D018139:Simplexvirus / Q000187:drug effects / Q000502:physiology; D014764:Viral Proteins; D014779:Virus Replication / Q000187:drug effects
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D046911:Macromolecular Substances; D014764:Viral Proteins; D019915:DNA Primase; C062021:helicase-primase, Human herpesvirus 1; D004265:DNA Helicases; D000212:Acyclovir