title: [Changes of serum cardiac troponin T in patients undergoing cardiac surgery].
abstract: We detected the changes of serum cardiac troponin T(cTn T) content and serum cardiac enzyme activities in 15 patients with cardiopulmonary bypass during cardiac operation. The central venous blood samples were collected to measure the serum concentration of cTn T by enzyme immunoassay methods and activities of lactate dehydrogenase(LDH), creatine kinase(CK), and creatine kinase isoenzyme(CK-MB) by biochemical methods. The content of cTn T and activities of LDH, CK, and CK-MB increased significantly after cardiac surgery. There was positive correlation between cTn T and aortic cross clamping time (r = 0.6014, P < 0.05), but there was no correlation between CK-MB and aortic cross clamping time (r = 0.4712, P > 0.05). We conclude that serum cTn T and CK-MB can monitor cardiac ischemic reperfusion injury and can evaluate myocardial protection methods during cardiac operation, but cTn T is better than CK-MB.
authors.affiliation: Department of Anesthesiology, Xiangya Hospital, Hunan Medical University, Changsha 410008.
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Cai
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Tan
mesh_terms: D000293:Adolescent; D000328:Adult; D001219:Aspartate Aminotransferases / Q000097:blood; D002315:Cardiopulmonary Bypass; D002648:Child; D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood; D052279:Creatine Kinase, MB Form; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000097:blood* / Q000601:surgery; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D009206:Myocardium / Q000201:enzymology; D020107:Troponin T / Q000097:blood*
chemical_list: D007527:Isoenzymes; D020107:Troponin T; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form