title: Castleman's disease of the buccal mucosa: report of a case and review of the literature of head and neck cases.
abstract: A case of Castleman's disease occurring in the buccal mucosa is described. An 84-year-old woman noticed that a mass in the left buccal mucosa that had been present for half a year. Computed tomography revealed a well-demarcated submucosal tumor, measuring 4.0 x 3.0 x 2.0 cm. The patient received no treatment at this time, and continued growth of the mass was observed. After incisional biopsy, the lesion was surgically removed. Histologically, the tumor consisted of an enlarged lymph node with conspicuous lymph follicles, in which vascular channels and deposits of eosinophilic material were noted. Laboratory examination showed an increase of serum antibody level of cytomegalovirus but of no other viruses. The patient was followed up for 1(1/2) years, with no clinical evidence of recurrence. This is the first report of Castleman's disease presenting in an oral site.
authors.affiliation: Department of Pathology, Faculty of Dentistry, Niigata University, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Maruyama
authors.forename: Natsuko
authors.initials: N
authors.lastname: Hao
authors.forename: Jun
authors.initials: J
authors.lastname: Cheng
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Horino
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohnishi
authors.forename: Masaya
authors.initials: M
authors.lastname: Fukushi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Fujii
authors.forename: Takashi
authors.initials: T
authors.lastname: Saku
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005871:Castleman Disease / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D009059:Mouth Diseases / Q000473:pathology* / Q000601:surgery; D009061:Mouth Mucosa / Q000473:pathology*