title: Pharmacologic prophylaxis and treatment of stress ulcers in critically ill patients.
abstract: Most clinicians agree that critically ill patients are at significant risk of developing stress-related ulcers and may have already developed mucosal lesions even if they are asymptomatic. Many options, including new pharmacologic advances, are available for the treatment and prophylaxis of stress-related ulcers; therefore, all critically ill patients should receive prophylaxis, even if they do not require treatment. Nutrition may play a significant role in the future in preventing stress-related ulcers. By improving stores of critical elements such as antioxidants, vitamins, and minerals before surgery, patients may lower the risk of developing stress ulcers. Critical care clinicians are critical in preventing and treating stress-related ulcers and should be vigilant in their patient care.
authors.affiliation: School of Nursing, Florida State University, Tallahassee 32306-4310, USA. jflanner@mailer.fsu.edu
authors.forename: Jeanne
authors.initials: J
authors.lastname: Flannery
authors.forename: Denise A
authors.initials: DA
authors.lastname: Tucker
mesh_terms: D000863:Antacids / Q000627:therapeutic use*; D003422:Critical Care; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D010437:Peptic Ulcer / Q000188:drug therapy / Q000209:etiology / Q000451:nursing / Q000517:prevention & control; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications*
chemical_list: D000863:Antacids; D006635:Histamine H2 Antagonists