title: Dose-intensive chemotherapy with syngeneic peripheral blood stem cell support for poor risk germ cell tumor of extragonadal origin: a case report.
abstract: A variety of regimens of high-dose chemotherapy with hematopoietic stem cell support for poor risk germ cell tumors have been established. However, a series of chemotherapy steps carried out prior to the harvest sometimes leads to an insufficient number of peripheral blood stem cells. Here, we report a case of a patient who successfully underwent high-dose chemotherapy for the treatment of poor risk extragonadal germ cell tumor by receiving peripheral blood stem cell transplantation donated from his genomically identical twin brother.
authors.affiliation: Department of Urology, Kyoto University Hospital, Kyoto, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Shingo
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Eijiro
authors.initials: E
authors.lastname: Nakamura
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kamato
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kakehi
authors.forename: Osamu
authors.initials: O
authors.lastname: Ogawa
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Ito
authors.forename: Takuo
authors.initials: T
authors.lastname: Fukuyama
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Hishizawa
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Ichinohe
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008207:Lymphatic Metastasis; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy*; D012307:Risk Factors; D014185:Transplantation, Isogeneic; D016896:Treatment Outcome
chemical_list: D005047:Etoposide; D002945:Cisplatin; D007069:Ifosfamide