title: An aggressive treatment for aggressive digital papillary adenocarcinoma.
abstract: Aggressive digital papillary adenoma (ADPA) and adenocarcinoma (ADPAca) are adnexal tumors that are not often recognized because of their rarity. We present a rare case of ADPAca involving the left middle finger of a 43-year-old man. Histopathological features of ADPAca are distinct from those of other eccrine sweat gland tumors; however, ADPAca may be misdiagnosed particularly for a metastasis of papillary adenocarcinoma originating in the colon, thyroid, or breast. Clinicopathological correlation is essential to ule out a possible risk of metastatic carcinoma of the skin. Recognition of these tumors is important because of a potential risk of local recurrence nd distant metastases. Aggressive surgical treatment consisting of digit amputation is advocated in the treatment of ADPAca.
authors.affiliation: Department of Dermatology, University of Wales College of Medicine, Cardiff, South Wales, United Kingdom.
authors.forename: H Serhat
authors.initials: HS
authors.lastname: Inaloz
authors.forename: G K
authors.initials: GK
authors.lastname: Patel
authors.forename: Arthur G
authors.initials: AG
authors.lastname: Knight
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000671:Amputation, Surgical; D001706:Biopsy; D002272:Carcinoembryonic Antigen / Q000032:analysis; D005385:Fingers / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D009418:S100 Proteins / Q000032:analysis; D013544:Sweat Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D013545:Sweat Glands / Q000473:pathology
chemical_list: D002272:Carcinoembryonic Antigen; D009418:S100 Proteins