title: Block the FAS, lose the fat.
authors.forename: Charles V
authors.initials: CV
authors.lastname: Mobbs
authors.forename: Hideo
authors.initials: H
authors.lastname: Makimura
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D019440:Anti-Obesity Agents / Q000494:pharmacology*; D002569:Cerulenin / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D064429:Fatty Acid Synthases / Q000037:antagonists & inhibitors*; D006801:Humans; D007031:Hypothalamus / Q000187:drug effects / Q000503:physiopathology; D051379:Mice; D008820:Mice, Obese; D008954:Models, Biological; D009765:Obesity / Q000188:drug therapy* / Q000201:enzymology* / Q000503:physiopathology
chemical_list: C406734:4-methylene-2-octyl-5-oxofuran-3-carboxylic acid; D019440:Anti-Obesity Agents; D004791:Enzyme Inhibitors; D002569:Cerulenin; D064429:Fatty Acid Synthases; D015107:4-Butyrolactone