[Glycyrrhizinic Acid Reference Standard (Control 001) of National Institute of Health Sciences].
The raw material of glycyrrhizinic acid was examined for preparation of the "Glycyrrhizinic Acid Reference Standard". The analytical data obtained were: UV spectrum: lambda max, 251 nm; and specific absorbance (E1ca1%) in ethanol at 251 nm, 146; IR spectrum, specific absorptions at 1714, 1655, 1215, and 1170 cm-1; and the spectrum of raw material was consistent with that of Standard (Control 991). Also, thin-layer chromatography, no impurity was detected; high-performance liquid chromatography, several impurities were detected. The amount of each impurity was estimated at less than 0.2% and total amount of impurities was less than 0.4%. Based on the above results, the candidate material was authorized as the Glycyrrhizinic Acid Reference Standard (Control 001) of the National Institute of Health Sciences.
Koide
T
T
Iwata
M
M
Maekawa
K
K
Saito
H
H
Tanimoto
T
T
Okada
S
S
D002851:Chromatography, High Pressure Liquid; D019695:Glycyrrhizic Acid / Q000032:analysis / Q000592:standards*; D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards; D012015:Reference Standards
D019695:Glycyrrhizic Acid