title: Psychiatric diagnoses among Mission Indian children with and without a parental history of alcohol dependence.
abstract: OBJECTIVE
  The primary goal was to determine whether Mission Indian children of alcoholics (COAs) have higher rates of psychiatric disorders than Mission Indian non-COAs. A secondary goal was to explore associations of other familial variables with rates of childhood psychiatric disorders.
  
  
  METHODS
  Psychiatric diagnoses were obtained from the primary caregiver, using the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA), for 117 (63 female) Mission Indian children; 81 of the children were interviewed directly. Of the 117 subjects, 92 (79%) were COAs and 25 (21%) were not.
  
  
  RESULTS
  There were no differences in rates of psychiatric disorders between COAs and non-COAs. Living in a household without a mother was associated with a higher rate of separation anxiety disorder, and living in a household without a father was associated with a higher rate of both oppositional defiant disorder and separation anxiety disorder.
  
  
  CONCLUSIONS
  Parental alcohol dependence does not appear to relate to increased psychopathology among Mission Indian children, but living in a single parent household may be associated with increased rates of some psychiatric disorders.
authors.affiliation: Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Gilder
authors.forename: Tamara L
authors.initials: TL
authors.lastname: Wall
authors.forename: Cindy L
authors.initials: CL
authors.lastname: Ehlers
mesh_terms: D000293:Adolescent; D000437:Alcoholism / Q000453:epidemiology / Q000235:genetics* / Q000523:psychology*; D016009:Chi-Square Distribution; D002648:Child; D005260:Female; D006801:Humans; D007198:Indians, North American / Q000235:genetics / Q000523:psychology* / Q000706:statistics & numerical data; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology / Q000235:genetics / Q000523:psychology*