title: An efficient chemical synthesis of nicotinamide riboside (NAR) and analogues.
abstract: A simple and efficient synthesis of nicotinamide riboside (NAR) 1 and derivatives 4 and 5 via trimethylsilyl trifluoromethanesulfonate (TMSOTf)-mediated N-glycosilation followed by spontaneous deacetylation by treating with methanol is reported.
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, Osaka Prefecture University, 1-1 Gakuen-cho, Sakai, 599-8531, Osaka, Japan. tanimori@biochem.osakafu-u.ac.jp
authors.forename: Shinji
authors.initials: S
authors.lastname: Tanimori
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ohta
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Kirihata
mesh_terms: D000107:Acetylation; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D011726:Pyridinium Compounds
chemical_list: D011726:Pyridinium Compounds; C018613:nicotinamide-beta-riboside; D009536:Niacinamide