TGF-beta-mediated control of allergen-specific T-cell responses.
Control of allergen-specific response by suppressive cytokines involves several layers of regulation, including secretion of the cytokine, deviation of cytokine expression by altered T-cell differentiation, immediate (de-) phosphorylation events upon binding of suppressive cytokines, and laterations in susceptibility of suppression.
Schmidt-Weber
Carsten B
CB
Swiss Institute of Allergy and Asthma Research, Obere Str. 22, CH-7270, Davos, Switzerland. csweber@siaf.unizh.ch
Kunzmann
Steffen
S
Blaser
Kurt
K
D000485:Allergens / Q000276:immunology*; D000818:Animals; D016207:Cytokines / Q000502:physiology; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D016212:Transforming Growth Factor beta / Q000502:physiology*
D000485:Allergens; D016207:Cytokines; D016212:Transforming Growth Factor beta