title: Reference intervals for a complete blood count determined on different automated haematology analysers: Abx Pentra 120 Retic, Coulter Gen-S, Sysmex SE 9500, Abbott Cell Dyn 4000 and Bayer Advia 120.
abstract: We processed 317 samples from healthy adult volunteers for a complete blood count, including leukocyte differentials and reticulocyte parameters, through five new-generation haematology analysers: Abx Pentra 120 Retic, Coulter Gen-S, Sysmex SE 9500, Abbott Cell Dyn 4000 and Bayer Advia 120. From these data non-parametric 2.5-97.5 percentile reference intervals were calculated for all parameters on all analysers. Some differences were found compared with previously reported reference intervals. Reference intervals for platelet parameters and reticulocytes agreed with these usually accepted. For red blood cell parameters, including haemoglobin and haematocrit, and white blood cell count, including absolute white blood cell differentials, our calculated reference intervals were in agreement with less frequently cited earlier reports, but were lower compared to the usually accepted reference intervals.
authors.affiliation: Clinical Laboratory, Algemeen Ziekenhuis Middelheim, Antwerpen, Belgium. vandenbossche@mail.com
authors.forename: Jan
authors.initials: J
authors.lastname: Van den Bossche
authors.forename: Katrien
authors.initials: K
authors.lastname: Devreese
authors.forename: Ronald
authors.initials: R
authors.lastname: Malfait
authors.forename: Martine
authors.initials: M
authors.lastname: Van de Vyvere
authors.forename: Annick
authors.initials: A
authors.lastname: Wauters
authors.forename: Hugo
authors.initials: H
authors.lastname: Neeis
authors.forename: Pieter
authors.initials: P
authors.lastname: De Schouwer
mesh_terms: D000328:Adult; D001331:Automation / Q000295:instrumentation; D015982:Bias; D001772:Blood Cell Count / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D015203:Reproducibility of Results