Neonatal encephalopathy in the term infant: neuroimaging and inflammatory cytokines.
The interrelationship between inflammation and ischemia is complex and poorly understood in the developing nervous system. In the preterm newborn, maternal infection may predispose to white matter injury and may be associated with cytokine elevation. In the term infant, few studies exist linking elevation of cytokines with encephalopathy and poor neurodevelopmental outcome. This review discusses the interplay among inflammatory cytokines, neonatal encephalopathy, and neuroimaging parameters.
Foster-Barber
Audrey
A
Neonatal Brain Disorders Laboratory, Department of Neurology, University of California at San Francisco, San Francisco, California 94143-0114, USA. dmf@itsa.ucsf.edu
Ferriero
Donna M
DM
D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000097:blood / Q000209:etiology*; D001930:Brain Injuries / Q000209:etiology*; D002547:Cerebral Palsy / Q000175:diagnosis* / Q000209:etiology; D016207:Cytokines / Q000097:blood / Q000502:physiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D011247:Pregnancy
D016207:Cytokines