title: In vitro gastrointestinal digestion study of pomegranate juice phenolic compounds, anthocyanins, and vitamin C.
abstract: Pomegranate is an important source of bioactive compounds, such as anthocyanins, other phenolic compounds, and ascorbic acid. In the present work an in vitro availability method has been used to assay the influence of the physiological conditions in the stomach and small intestine. This method enables the study of the release of anthocyanins, vitamin C, and total phenols from the pomegranate juice and their transformations during gastrointestinal digestion. Results have shown that pomegranate phenolic compounds are available during the digestion in a quite high amount (29%). Nevertheless, due to pH, anthocyanins are largely transformed into non-red forms and/or degraded (97%), and similar results are obtained for vitamin C (>95% degradation).
authors.affiliation: Laboratorio Fitoquímica, Departamento Ciencia y Tecnología de los Alimentos, CEBAS-CSIC, Apartado 4195, 30080 Murcia, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Pérez-Vicente
authors.forename: Angel
authors.initials: A
authors.lastname: Gil-Izquierdo
authors.forename: Cristina
authors.initials: C
authors.lastname: García-Viguera
mesh_terms: D000872:Anthocyanins / Q000032:analysis / Q000378:metabolism*; D001205:Ascorbic Acid / Q000032:analysis / Q000378:metabolism*; D001628:Beverages; D001682:Biological Availability; D002851:Chromatography, High Pressure Liquid; D004063:Digestion; D004064:Digestive System / Q000378:metabolism; D005638:Fruit / Q000737:chemistry; D066298:In Vitro Techniques; D029594:Onagraceae / Q000737:chemistry*; D010194:Pancreatin / Q000378:metabolism; D010434:Pepsin A / Q000378:metabolism; D010636:Phenols / Q000032:analysis / Q000378:metabolism*
chemical_list: D000872:Anthocyanins; D010636:Phenols; D010194:Pancreatin; D010434:Pepsin A; D001205:Ascorbic Acid