title: [Ethological examination of Alzheimer's disease model rats treated with bushen yizhi decoction].
abstract: OBJECTIVE
  To explore the ethological improving effect of Bushen Yizhi Decoction (BSYZD) in treating model rat of Alzheimer's disease (AD).
  
  
  METHODS
  Ethologic examination was carried out with Morris water maze on young, aged, AD model, Huperzine A treated and BSYZD treated groups of rats.
  
  
  RESULTS
  In the BSYZD treated group, the escape latency (EL) curve placed between that of the young, aged and AD model, Huperzine A treated group; the percentage of middle circle swim path, the 40 cm circle swimming time, and the platform-crossing times were not different from those in the normal aged group, but were different significantly as compared with the AD model group, P < 0.05.
  
  
  CONCLUSIONS
  BSYZD could ameliorate the behavior deficits of AD model.
authors.affiliation: Department of Neurobiology, Faculty of Anatomy, Shandong Medical University, Jinan 250012.
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Lai
authors.forename: J
authors.initials: J
authors.lastname: Sun
mesh_terms: D000544:Alzheimer Disease / Q000523:psychology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D008297:Male; D018782:Maze Learning; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004365:Drugs, Chinese Herbal