Probable mother-to-infant transmission of Pneumocystis carinii f. sp. hominis infection.
A mother and her 4.5-week-old infant had Pneumocystis carinii pneumonia contemporaneously. Genotyping of P. carinii f. sp. hominis DNA at three independent loci showed the same genotype in samples from mother and infant. These data suggest transmission of P. carinii organisms from the mother to her infant.
Miller
Robert F
RF
Department of Sexually Transmitted Diseases, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School, University College, London, United Kingdom.
Ambrose
Helen E
HE
Novelli
Vas
V
Wakefield
Ann E
AE
D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D004271:DNA, Fungal / Q000032:analysis; D005260:Female; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D011010:Pneumocystis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D011020:Pneumonia, Pneumocystis / Q000382:microbiology / Q000635:transmission*; D016133:Polymerase Chain Reaction
D004271:DNA, Fungal