Dose-intensive chemotherapy with syngeneic peripheral blood stem cell support for poor risk germ cell tumor of extragonadal origin: a case report.
A variety of regimens of high-dose chemotherapy with hematopoietic stem cell support for poor risk germ cell tumors have been established. However, a series of chemotherapy steps carried out prior to the harvest sometimes leads to an insufficient number of peripheral blood stem cells. Here, we report a case of a patient who successfully underwent high-dose chemotherapy for the treatment of poor risk extragonadal germ cell tumor by receiving peripheral blood stem cell transplantation donated from his genomically identical twin brother.
Kobayashi
Takashi
T
Department of Urology, Kyoto University Hospital, Kyoto, Japan.
Yamamoto
Shingo
S
Nakamura
Eijiro
E
Kamato
Toshiyuki
T
Kakehi
Yoshiyuki
Y
Ogawa
Osamu
O
Ito
Noriyuki
N
Fukuyama
Takuo
T
Hishizawa
Masakatsu
M
Ichinohe
Tatsuo
T
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008207:Lymphatic Metastasis; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy*; D012307:Risk Factors; D014185:Transplantation, Isogeneic; D016896:Treatment Outcome
D005047:Etoposide; D002945:Cisplatin; D007069:Ifosfamide