title: Circulating monocyte chemoattractant protein-1 in heart transplant recipients with cardiac allograft vasculopathy.
abstract: OBJECTIVE
  To evaluate serum Monocyte Chemoattractant Protein-1 (MCP-1) as a biologic marker of cardiac allograft vasculopathy (CAV) in heart transplant recipients (HTR).
  
  
  METHODS
  Serum levels of MCP-1 were measured in 49 HTR with and without CAV.
  
  
  RESULTS
  HTR exhibited significantly higher serum MCP-1 levels than controls. However, no difference was observed according to the existence of CAV.
  
  
  CONCLUSIONS
  Serum MCP-1 levels do not constitute a marker of the CAV occurring after heart transplantation.
authors.affiliation: Service de Biochimie C, Groupe hospitalier Pitié-Salpêtrière, 83 boulevard de l'hôpital, 75013, Paris, France. jean-louis.beaudeux@psl.ap-hop-paris.fr
authors.forename: Jean Louis
authors.initials: JL
authors.lastname: Beaudeux
authors.forename: Richard
authors.initials: R
authors.lastname: Dorent
authors.forename: Maguy
authors.initials: M
authors.lastname: Bernard
authors.forename: Mary
authors.initials: M
authors.lastname: Reagan
authors.forename: Marie José
authors.initials: MJ
authors.lastname: Foglietti
authors.forename: Iradj
authors.initials: I
authors.lastname: Gandjbakhch
authors.forename: Patrice
authors.initials: P
authors.lastname: Cacoub
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood*; D018932:Chemokine CCL2 / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood*; D019040:E-Selectin / Q000097:blood; D004730:Endothelium, Vascular / Q000473:pathology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D019007:P-Selectin / Q000097:blood; D014184:Transplantation, Homologous; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood
chemical_list: D015415:Biomarkers; D018932:Chemokine CCL2; D019040:E-Selectin; D019007:P-Selectin; D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1