title: Response to paclitaxel and carboplatin in metastatic salivary gland cancer: a case report.
abstract: BACKGROUND
  Malignant tumors of the salivary gland are rare entities that are treated primarily by surgical resection. For patients with recurrent or unresectable disease, options include radiation therapy or chemotherapy; however, responses are few and of short duration. Patients with metastatic disease have been treated with chemotherapy, but, again, response rates have been low and of short duration.
  
  
  METHODS
  A 52-year-old man was seen with a mass on his tongue. A biopsy revealed adenocarcinoma of a minor salivary gland. Ten months after surgical resection, neck dissection, and radiation therapy, the patient was found to have metastatic disease to the lung. Chemotherapy was initiated with carboplatin and paclitaxel.
  
  
  RESULTS
  The patient obtained a complete response after six cycles of carboplatin and paclitaxel.
  
  
  CONCLUSIONS
  The use of carboplatin and paclitaxel in the setting of metastatic salivary gland cancer is a viable option.
authors.affiliation: Hematology and Oncology, Cardinal Bernadin Cancer Center, Loyola University Medical Center, 2160 South First Avenue, Maywood, Illinois, USA.
authors.forename: Janet C
authors.initials: JC
authors.lastname: Ruzich
authors.forename: Marlyn C
authors.initials: MC
authors.lastname: Ciesla
authors.forename: Joseph I
authors.initials: JI
authors.lastname: Clark
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use*; D012468:Salivary Gland Neoplasms / Q000188:drug therapy* / Q000556:secondary; D016896:Treatment Outcome
chemical_list: D016190:Carboplatin; D017239:Paclitaxel