[Serum lipids, lipoprotein and stroke].
The serum levels of lipids and lipoproteins were measured in 180 consecutive patients with acute stroke(90 hemorrhagic stroke, 90 ischemic stroke) and 107 age- and sex-matched controls. As compared with the control group, hemorrhagic group had lower levels of total cholesterol(TC) (P < 0.05), low density lipoprotein-cholesterol(LDL-C) (P < 0.01) and Lp(a) (P < 0.05) while the ischemic group had higher serum TC(P < 0.05), LDL-C(P < 0.01), Lp(a) (P < 0.01) and lower high density lipoprotein-cholesterol(HDL-C) (P < 0.05) and ApoAI(P < 0.01). Multiple factor logistic regression showed that cigarette smoking, hypertension and family history of stroke were the common risk factors for both hemorrhagic and ischemic stroke, and that lowered TC and elevated LP(a) levels were independent risk factors for hemorrhagic stroke and ischemic stroke respectively.
Peng
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Department of Cardiology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Zhao
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S
D000328:Adult; D000368:Aged; D016632:Apolipoprotein A-I / Q000097:blood; D002543:Cerebral Hemorrhage / Q000097:blood*; D002544:Cerebral Infarction / Q000097:blood; D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D017270:Lipoprotein(a) / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000097:blood*
D016632:Apolipoprotein A-I; D017270:Lipoprotein(a); D008075:Lipoproteins, HDL; D002784:Cholesterol