title: Scytonemin--a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases.
authors.affiliation: University of California Santa Barbara, Department of Ecology, Evolution, and Marine Biology, 93106, USA. Christopher.S.Stevenson@gsk.com
authors.forename: C S
authors.initials: CS
authors.lastname: Stevenson
authors.forename: E A
authors.initials: EA
authors.lastname: Capper
authors.forename: A K
authors.initials: AK
authors.lastname: Roshak
authors.forename: B
authors.initials: B
authors.lastname: Marquez
authors.forename: K
authors.initials: K
authors.lastname: Grace
authors.forename: W H
authors.initials: WH
authors.lastname: Gerwick
authors.forename: R S
authors.initials: RS
authors.lastname: Jacobs
authors.forename: L A
authors.initials: LA
authors.lastname: Marshall
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins; D002455:Cell Division / Q000187:drug effects; D000458:Cyanobacteria / Q000737:chemistry; D004730:Endothelium, Vascular / Q000166:cytology; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D007211:Indoles / Q000494:pharmacology* / Q000627:therapeutic use; D007249:Inflammation / Q000188:drug therapy / Q000201:enzymology* / Q000473:pathology*; D007527:Isoenzymes / Q000037:antagonists & inhibitors; D008297:Male; D051379:Mice; D010636:Phenols / Q000494:pharmacology* / Q000627:therapeutic use; D010860:Pigments, Biological; D011493:Protein Kinase C / Q000037:antagonists & inhibitors; D064546:Protein Kinase C beta; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins; D011994:Recombinant Proteins; D014471:Umbilical Veins; D000097869:Polo-Like Kinase 1
chemical_list: D018797:Cell Cycle Proteins; D004791:Enzyme Inhibitors; D007211:Indoles; D007527:Isoenzymes; D010636:Phenols; D010860:Pigments, Biological; D011493:Protein Kinase C; D064546:Protein Kinase C beta; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins; D011994:Recombinant Proteins; D000097869:Polo-Like Kinase 1; C083368:scytonemin