title: In defense of Phase I trials.
authors.forename: V
authors.initials: V
authors.lastname: Lévy
authors.forename: S
authors.initials: S
authors.lastname: Chevret
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D017321:Clinical Trials, Phase I as Topic; D004992:Ethics, Medical; D006801:Humans; D020714:Maximum Tolerated Dose; D009369:Neoplasms / Q000188:drug therapy; D017410:Practice Guidelines as Topic
chemical_list: D000970:Antineoplastic Agents