title: High malaria transmission intensity in a village close to Yaounde, the capital city of Cameroon.
abstract: A 2-yr longitudinal malaria study was undertaken in a suburb of Yaounde, the capital city of Cameroon, in the village of Simbock, approximately 2 km from the city limits. This study allowed assessment of malaria transmission intensity and dynamics in this region before implementation of pyrethroid impregnated bed nets through the national vector control program. Anophelines were captured on human volunteers by pyrethrum spray collections and in resting sites outdoors. Malaria vectors were Anopheles funestus Giles, Anopheles gambiae s.s. Giles (M and S forms), Anopheles moucheti Evans, and Anopheles nili Theobald. An. moucheti was the most abundant mosquito captured during the study, accounting for >54% of total anophelines caught. The annual Plasmodium falciparum Welch entomological inoculation rates measured by enzyme-linked immunosorbent assay were 277 infected bites per human for the first year and 368 for the second year. An. gambiae s.s., An. funestus, An. moucheti, and An. nili were responsible for 23.8%, 26.8%, 39.2%, and 10.2% of malaria transmission, respectively. Malaria transmission is perennial throughout the year. All these vectors were highly anthropophagous because only two out of 566 mosquitoes blood-meal tested were not taken on humans.
authors.affiliation: Organisation de Coordination pour la Lutte Contre les Endémies en Afrique Centrale, Yaoundé, Cameroon.
authors.forename: Christophe
authors.initials: C
authors.lastname: Antonio-Nkondjio
authors.forename: Parfait
authors.initials: P
authors.lastname: Awono-Ambene
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Toto
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Meunier
authors.forename: Sylvie
authors.initials: S
authors.lastname: Zebaze-Kemleu
authors.forename: Rose
authors.initials: R
authors.lastname: Nyambam
authors.forename: Charles S
authors.initials: CS
authors.lastname: Wondji
authors.forename: Timoléon
authors.initials: T
authors.lastname: Tchuinkam
authors.forename: Didier
authors.initials: D
authors.lastname: Fontenill
mesh_terms: D000818:Animals; D000852:Anopheles; D002163:Cameroon; D005260:Female; D006801:Humans; D007299:Insect Bites and Stings; D007303:Insect Vectors; D008137:Longitudinal Studies; D016778:Malaria, Falciparum / Q000469:parasitology / Q000635:transmission*; D010963:Plasmodium falciparum / Q000302:isolation & purification; D015800:Protozoan Proteins / Q000032:analysis
chemical_list: D015800:Protozoan Proteins; C041595:circumsporozoite protein, Protozoan