title: An expanding role for cardiopulmonary bypass in trauma.
abstract: OBJECTIVE
  To analyze experience at the McGill University Health Centre with cardiopulmonary bypass (CPB) in trauma, complemented by a review of the literature to define its role globally and outline indications for its expanded use in trauma management.
  
  
  METHODS
  All available published English-language articles from peer reviewed journals, located using the MEDLINE database. Chapters from relevant, current textbooks were also utilized.
  
  
  METHODS
  Nine relevant case reports, original articles or reviews pertaining to the use of CPB in trauma.
  
  
  METHODS
  Original data as well as authors' opinions pertinent to the application of CPB to trauma were extracted, incorporated and appropriately referenced in our review.
  
  
  RESULTS
  Overall mortality in the selected series of CPB used in the trauma setting was 44.4%. Four of 5 survivors had CPB instituted early (first procedure in operative management) whereas 3 of 4 deaths involved late institution of CPB.
  
  
  CONCLUSIONS
  Although CPB has traditionally been used in the setting of cardiac trauma alone, a better understanding of its potential benefit in noncardiac injuries will likely make for improved outcomes in the increasingly diverse number of severely injured patients seen in trauma centres today. Further studies by other trauma centres will allow for standardized indications for the use of CPB in trauma.
authors.affiliation: Division of General Surgery, McGill University, Montreal, Que.
authors.forename: Talat S
authors.initials: TS
authors.lastname: Chughtai
authors.forename: Miroslav S
authors.initials: MS
authors.lastname: Gilardino
authors.forename: David M
authors.initials: DM
authors.lastname: Fleiszer
authors.forename: David C
authors.initials: DC
authors.lastname: Evans
authors.forename: Rea A
authors.initials: RA
authors.lastname: Brown
authors.forename: David S
authors.initials: DS
authors.lastname: Mulder
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001808:Blood Vessels / Q000293:injuries; D001980:Bronchi / Q000293:injuries / Q000601:surgery; D002315:Cardiopulmonary Bypass / Q000379:methods; D005260:Female; D006335:Heart Injuries / Q000601:surgery; D006801:Humans; D007035:Hypothermia / Q000601:surgery; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation; D012131:Respiratory Insufficiency / Q000601:surgery; D012769:Shock / Q000601:surgery; D014132:Trachea / Q000293:injuries / Q000601:surgery; D014947:Wounds and Injuries / Q000601:surgery*; D014949:Wounds, Nonpenetrating / Q000601:surgery; D014950:Wounds, Penetrating / Q000601:surgery