title: [Replacement of bone defects with a polyurethane composition with hydroxyapatite high-filling ].
abstract: There have been obtained high-filling polyurethane compositions with hydroxyapatite. Compositions with hydroxyapatite and immunomodulator in the polyurethane base acquire better adhesiveness and improved strength characteristics as evidenced by physical-and-clinical studies made. Modal operations are developed in test animals on bone defects replacing that carry a high mechanical load. Histological studies showed that polyuretane-base high-filling polymeric compositions replace the loss of bone fully, stimulate the processes of bone formation, with no negative responses of the osseous tissue noted.
authors.forename: R A
authors.initials: RA
authors.lastname: Rozhnova
authors.forename: V I
authors.initials: VI
authors.lastname: Bondarchuk
authors.forename: E S
authors.initials: ES
authors.lastname: Savitskaia
authors.forename: E G
authors.initials: EG
authors.lastname: Levenets
authors.forename: V A
authors.initials: VA
authors.lastname: Popov
authors.forename: N A
authors.initials: NA
authors.lastname: Galatenko
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001843:Bone Cements; D001847:Bone Diseases / Q000628:therapy; D017886:Durapatite; D020007:Implants, Experimental; D011140:Polyurethanes; D011817:Rabbits
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D011140:Polyurethanes; D017886:Durapatite
vernacular_title: Zameshchenie kostnykh defektov poliuretanovoĭ kompozitsieĭ s vysokim napoleniem gidroksiapatitom.