title: Cardiorespiratory fitness and stroke mortality in men.
abstract: OBJECTIVE
  We examined the association between cardiorespiratory fitness and stroke mortality in men.
  
  
  METHODS
  This is a prospective cohort study. We followed 16,878 men, ages 40-87 yr, who had a complete medical evaluation including a maximal treadmill exercise test and self-reported health habits. There were 32 stroke deaths during an average of 10 yr of follow-up (167,961 man-yr).
  
  
  RESULTS
  After adjustment for age and examination year, there was an inverse association between cardiorespiratory fitness and stroke mortality (P = 0.005 for trend). This association remained after further adjustment for cigarette smoking, alcohol intake, body mass index, hypertension, diabetes mellitus, and parental history of coronary heart disease (P = 0.02 for trend). High-fit men (most fit 40%) had 68% (95% CI: 0.12, 0.82) and moderate-fit men had 63% (95% CI: 0.17, 0.83) lower risk of stroke mortality when compared with low-fit men (least fit 20%), respectively.
  
  
  CONCLUSIONS
  Moderate and high levels of cardiorespiratory fitness were associated with lower risk of stroke mortality in men in the Aerobics Center Longitudinal study population.
authors.affiliation: Department of Sports and Exercise Sciences, West Texas A & M University, Canyon, TX, USA.
authors.forename: Chong Do
authors.initials: CD
authors.lastname: Lee
authors.forename: Steven N
authors.initials: SN
authors.lastname: Blair
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002320:Cardiovascular Physiological Phenomena; D015331:Cohort Studies; D015444:Exercise / Q000502:physiology; D005500:Follow-Up Studies; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D010809:Physical Fitness / Q000502:physiology*; D011446:Prospective Studies; D012143:Respiratory Physiological Phenomena; D012306:Risk; D020521:Stroke / Q000401:mortality*; D014481:United States / Q000453:epidemiology