title: Two successful cases of bromide therapy for refractory symptomatic localization-related epilepsy.
abstract: Potassium bromide was tried for two children with daily convulsive focal motor seizures with unconsciousness and focal motor seizure status. The treatment resulted in complete cessation of the attacks. It has been reported that bromide is effective for generalized tonic-clonic seizures and not for complex partial seizures, such as convulsive focal motor seizures with unconsciousness. However, our experiences provide evidence that bromide is one of the useful therapeutic agents for intractable symptomatic localization-related epilepsy.
authors.affiliation: Department of Pediatrics, Sendai City Hospital, 3-1 Shimizukoji, Wakabayashi-ku, Sendai, Miyagi, Japan. mtakayanagi@ped.med.tohoku.ac.jp
authors.forename: Masaru
authors.initials: M
authors.lastname: Takayanagi
authors.forename: Katsuya
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Mitsutoshi
authors.initials: M
authors.lastname: Munakata
authors.forename: Rie
authors.initials: R
authors.lastname: Kato
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yokoyama
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Haginoya
authors.forename: Kazuie
authors.initials: K
authors.lastname: Iinuma
mesh_terms: D001965:Bromides / Q000627:therapeutic use*; D002648:Child; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D017680:Potassium Compounds / Q000627:therapeutic use*; D016896:Treatment Outcome; D014474:Unconsciousness
chemical_list: D001965:Bromides; D017680:Potassium Compounds; C039004:potassium bromide