Chemical composition and biological activity of the volatiles of Anthemis melampodina and Pluchea dioscoridis.
The volatile fractions obtained by hydrodistillation of the fresh leaves of Anthemis melampodina and Pluchea dioscoridis were analysed by GC-MS technique. Of 38 components identified in the volatile oil of A. melampodina, santolinatriene was the major component (27.33%). The oil was characterized by a high percentage of monoterpene hydrocarbons (49.94%) while sesquiterpene hydrocarbons and oxygenated sesquiterpenes represented only 7.41% and 11.43% of the oil. 36 components were identified in the volatile oil of P. dioscoridis. Farnesol was the major component (16.50%) accompanied by a high percentage of sesquiterpene alcohols. Oxygenated sesquiterpenes (26.43%) and sesquiterpene hydrocarbons (39.43%) represented the main constituents in the oil. P. dioscoridis showed a marked mosquito larvicidal activity against Culex pipiens (LC(50) 71.86 ppm), while A. melampodina was moderately active (LC(50) 139.42 ppm).
Grace
Mary H
MH
Chemistry of Natural and Microbial Products Department, National Research Centre, Dokki, Cairo, Egypt. mhgrace@thewayout.net
D000818:Animals; D019659:Asteraceae; D001681:Biological Assay; D009033:Culicidae / Q000187:drug effects*; D008401:Gas Chromatography-Mass Spectrometry; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry / Q000378:metabolism; D011722:Pyrethrins / Q000494:pharmacology; D012717:Sesquiterpenes / Q000032:analysis
D009822:Oils, Volatile; D011722:Pyrethrins; D012717:Sesquiterpenes; C051001:cyphenothrin