Malignant deciduoid mesothelioma of the pleura: report of two cases with long survival.
OBJECTIVE
To present two rare cases of malignant mesotheliomas with deciduoid features arising in the pleura, both with long survival.


RESULTS
These two cases of deciduoid mesotheliomas were observed in adult patients (one 73-year-old male and one 23-year-old female). Only the male had a history of occupational asbestos exposure, whereas the woman had a history of familial mesothelioma. A deciduoid morphology was predominant and focal areas with tubular-papillary features were noted. The tumour cells were positive for cytokeratins, HMBE-1, calretinin, EMA and mitochondrion antibodies. The follow-up data did not suggest a particularly poor prognosis; the mean survival observed was 23 months (17 and 39 months, respectively).


CONCLUSIONS
This deciduoid mesothelioma histological subtype does not appear to represent an unfavourable prognostic category.
Serio
G
G
Department of Pathological Anatomy and Genetics, University of Bari, Bari, Italy. g.serio@anatopat.uniba.it
Scattone
A
A
Pennella
A
A
Giardina
C
C
Musti
M
M
Valente
T
T
Pollice
L
L
D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D064032:Calbindin 2; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis; D019394:Ki-67 Antigen / Q000032:analysis; D008297:Male; D008654:Mesothelioma / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D008928:Mitochondria / Q000276:immunology; D010997:Pleural Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D064030:S100 Calcium Binding Protein G / Q000032:analysis; D016019:Survival Analysis; D013997:Time Factors
D000906:Antibodies; C576764:CALB2 protein, human; D064032:Calbindin 2; D019394:Ki-67 Antigen; D064030:S100 Calcium Binding Protein G; D007633:Keratins