Adaptation through translocation.
Papers by and, in this issue of Neuron, describe how massive and rapid translocation of specific elements of the phototransduction cascades in different phyla, namely, the G protein (transducin) in vertebrate rods and light-sensitive TRPL channels in the microvillar rhabdomeres of Drosophila, contribute to photoreceptor adaptation.
Hardie
Roger
R
Department of Anatomy, Cambridge University, Downing Street, Cambridge CB2 3DY, United Kingdom.
D000221:Adaptation, Ocular / Q000502:physiology*; D000818:Animals; D002148:Calmodulin-Binding Proteins / Q000378:metabolism*; D029721:Drosophila Proteins; D008565:Membrane Proteins / Q000378:metabolism*; D021381:Protein Transport / Q000502:physiology; D017948:Retinal Rod Photoreceptor Cells / Q000378:metabolism; D015293:Transducin / Q000378:metabolism*; D050051:Transient Receptor Potential Channels
D002148:Calmodulin-Binding Proteins; D029721:Drosophila Proteins; D008565:Membrane Proteins; D050051:Transient Receptor Potential Channels; C074192:trpl protein, Drosophila; D015293:Transducin