Separation of N-alkyl phenothiazine sulfones by HPTLC using an optimum mobile phase.
In high performance thin layer chromatography some form of optimization is necessary if complete separation of all components is required. The selection of mobile phase composition is one of the most important components of an optimization strategies. The aim of this paper is the separation of the N-alkyl phenothiazine sulfones by high performance thin layer chromatography using an optimum mobile phase system. The optimum composition of mobile phase (toluene-ethyl ether-chloroform, 30:50:20, v/v) are given by the maximum of objective function (F(obj)=10.6110).
Cimpoiu
Claudia
C
Faculty of Chemistry and Chemical Engineering, 'Babes-Bolyai' University, 11 Arany Janos, 3400, Cluj-Napoca, Romania
Hodisan
Sorin
S
Toşa
Monica
M
Paizs
Csaba
C
Majdik
Cornelia
C
Irimie
Florin-Dan
FD
D000465:Algorithms; D000478:Alkylation; D002855:Chromatography, Thin Layer; D010640:Phenothiazines / Q000032:analysis*; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet; D013450:Sulfones
D010640:Phenothiazines; D012997:Solvents; D013450:Sulfones