Callosotomy patients exhibit temporal uncoupling during continuous bimanual movements.
Rhythmic bimanual movements are highly constrained in the temporal domain, with the gestures of the two hands tightly synchronized. Previous studies have implicated a subcortical locus for temporal coupling based on the observation that these constraints persist in callosotomy patients. We now report that such coupling is restricted to movements entailing a discrete event (such as a movement onset). Three callosotomy patients exhibited a striking lack of temporal coupling during continuous movements, with the two hands oscillating at non-identical frequencies. We propose a subcortical locus of temporal coupling for movements involving discrete events. In contrast, synchronization between the hands during continuous movements depends on interhemispheric transmission across the corpus callosum.
Kennerley
Steven W
SW
University of California, Berkeley, 3210 Tolman Hall #1650, Berkeley, California 94720, USA.
Diedrichsen
Jörn
J
Hazeltine
Eliot
E
Semjen
Andras
A
Ivry
Richard B
RB
D000328:Adult; D003337:Corpus Callosum / Q000502:physiology* / Q000601:surgery*; D006225:Hand; D006801:Humans; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D013997:Time Factors