title: Fiber-optic biosensors--an overview.
abstract: This article reviews progress and developments during the past five years in the field of optical fiber biosensors. Because of the expense and time constraints associated with modern laboratory analysis, there is a growing need for real-time, low-cost technology that can be used industrially, environmentally, and clinically, and to monitor food processing. Miniaturization, integrated systems, and multianalyte determination have become key aspects of sensor development and efforts in this direction will also be discussed, with some pointers to likely directions of future research in the area. The review will provide information about the analytical characteristics and applications of fiber-optic biosensors classified depending on the biorecognition element employed - enzymes, whole cells, antibodies, nucleic acids, and biomimetic polymers.
authors.affiliation: Optical Sensors Group, Department of Analytical Chemistry, Faculty of Chemistry, Universidad Complutense de Madrid, 28040 Madrid, Spain.
authors.forename: Dolores
authors.initials: D
authors.lastname: Marazuela
authors.forename: María Cruz
authors.initials: MC
authors.lastname: Moreno-Bondi
mesh_terms: D015374:Biosensing Techniques; D004798:Enzymes / Q000378:metabolism; D005336:Fiber Optic Technology; D007118:Immunoassay / Q000295:instrumentation; D018716:Molecular Mimicry; D009696:Nucleic Acids / Q000032:analysis; D055100:Optical Fibers
chemical_list: D004798:Enzymes; D009696:Nucleic Acids