title: Adhesion formation: intraperitoneal catheters in surgical practice.
abstract: To compare the adhesion formation, in a rat model, of commercially available materials used as intraperitoneal catheters in clinical practice, pieces of polyurethane, Teflon, silicone, and polyvinyl chloride (PVC) were placed intraperitoneally in 36 female Wistar rats randomly assigned into four groups. Adhesion development was quantitated according to Nair's classification system (NCS). According to NCS, polyurethane showed the least adhesion formation, while the highest scores were found in the PVC group. Comparing the thickness and the firmness of adhesions in the four groups, significant differences were found, with the polyurethane group developing none or filmy and mild adhesions. In contrast, almost all the rats in the Teflon group developed thick and dense adhesions. Thus, polyurethane caused the least adhesion formation among the four materials evaluated, and can be used more extensively for the construction of catheters for prolonged intraperitoneal use.
authors.affiliation: 1st Propaedeutic Surgical Clinic, University of Athens, Hippocrateio Hospital, Greece.
authors.forename: George C
authors.initials: GC
authors.lastname: Zografos
authors.forename: Kreon M
authors.initials: KM
authors.lastname: Simeonidis
authors.forename: Aikaterini S
authors.initials: AS
authors.lastname: Parasi
authors.forename: Evangelos G
authors.initials: EG
authors.lastname: Messaris
authors.forename: Evangelos E
authors.initials: EE
authors.lastname: Menenakos
authors.forename: Ismene A
authors.initials: IA
authors.lastname: Dontas
authors.forename: Kiriaki C
authors.initials: KC
authors.lastname: Marti
authors.forename: George A
authors.initials: GA
authors.lastname: Androulakis
mesh_terms: D000818:Animals; D002404:Catheterization / Q000009:adverse effects*; D005260:Female; D010532:Peritoneal Diseases / Q000209:etiology*; D011138:Polytetrafluoroethylene / Q000009:adverse effects; D011140:Polyurethanes / Q000009:adverse effects; D011143:Polyvinyl Chloride / Q000009:adverse effects; D011183:Postoperative Complications / Q000517:prevention & control; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D012828:Silicones; D000267:Tissue Adhesions / Q000209:etiology
chemical_list: D011140:Polyurethanes; D012828:Silicones; D011138:Polytetrafluoroethylene; D011143:Polyvinyl Chloride