[Brain monoamine oxidase in prematurely aging OXYS rats].
Rats OXYS with manifestations of genetically determined premature aging and OXYR free from these manifestation were studied. Eight month old OXYS and OXYR rats were characterized by similar brain stem MAO A and MAO B activities and their control at the transcription level. In hemispheres of 8 month old OXYS rats MAO A activity was higher than in OXYR. Emotional stress did not affect either MAO A or MAO B in brain stem of the two strains, and lowered MAO A activity in hemispheres of OXYS rats.
Voĭtenko
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Institute of Cytology and Genetics, Siberian Branch, Russian Acad. Sci., Lavrenteva 10 av., 630090, Novosibirsk, Russia.
D000375:Aging / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology*; D005838:Genotype; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism; D008297:Male; D008995:Monoamine Oxidase / Q000235:genetics / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013315:Stress, Psychological / Q000201:enzymology; D014158:Transcription, Genetic
D007527:Isoenzymes; D008995:Monoamine Oxidase
Monoaminoksidaza mozga pri starenii u prezhdevremenno stareiushchikh krys linii OXYS.