Geometric scaling effects in electrical field flow fractionation. 2. Experimental results.
Geometric scaling of microelectrical field flow fractionation (micro-EFFF) systems is investigated experimentally and compared to theory and to macroscale EFFF systems. Experimental results are presented to demonstrate that the miniaturized system operates according to the scaling theory associated with the system. Demonstrated improvements in the channels include increased retention and resolution and decreased peak broadening, electrical time constants, relaxation time, power consumption, and sample size. Additionally, scaling effects related to the compression of separation zones in the miniaturized EFFF systems are discussed.
Gale
Bruce K
BK
Department of Mechanical Engineering, University of Utah, Salt Lake City 84112, USA. gale@mech.utah.edu
Caldwell
Karin D
KD
Frazier
A Bruno
AB
D004566:Electrodes; D004574:Electromagnetic Fields; D013058:Mass Spectrometry / Q000295:instrumentation*; D036103:Nanotechnology