[Effect of calcium and cristata L extracts on bone mineral density and urinary mineral of rats].
In order to study the effect of cristata L for preventing fluoride toxicity, forty male SD rats were randomly divided into five groups. The control group(NC) was fed with staple feed stuff and tap water, the other four groups were fed with staple feed-stuff and high fluorine water. Except the high fluorine group(F), the other groups were fed with cristata L(FC), high calcium(FCa) and cristata L with high calcium(FCCa) respectively. The results showed that the serum calcium, urinary sodium, calcium, hydroxyproline(HOP) and fluorine contents of high fluorine groups were higher than that of control group; and the urinary calcium content of high calcium group was higher than that of control group. The body weight, BMC and BMD of high fluorine groups was lower than that of control group. The weight of groups FC, FCa and FCCa were significantly higher than that of group F. The BMC and BMD of group FCCa were significantly higher than that of group F. This implies that the food high in fluorine can affect the bone mineral density and urinary minerals of rats, the food supplemented with calcium can reduce the effect of high fluorine, and the food supplemented with both calcium and cristata L is better.
Li
W
W
Xinxiang Medical College, Xinxiang 453003, China.
Yuan
Z
Z
D000818:Animals; D015519:Bone Density / Q000187:drug effects*; D002118:Calcium / Q000494:pharmacology* / Q000652:urine; D005458:Fluoride Poisoning / Q000517:prevention & control*; D005459:Fluorides / Q000652:urine*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
D010936:Plant Extracts; D005459:Fluorides; D002118:Calcium