Replication, recombination, and repair: going for the gold.
DNA recombination is now appreciated to be integral to DNA replication and cell survival. Recombination allows replication to successfully maneuver through the roadblocks of damaged or collapsed replication forks. The signals and controls that permit cells to transition between replication and recombination modes are now being identified.
Klein
Hannah L
HL
Department of Biochemistry, New York University School of Medicine, New York, NY 10016, USA. hannah.klein@md.nyu.edu
Kreuzer
Kenneth N
KN
D000818:Animals; D005075:Biological Evolution; D004247:DNA / Q000235:genetics / Q000378:metabolism*; D004261:DNA Replication / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D009687:Nuclear Proteins / Q000378:metabolism*; D011995:Recombination, Genetic / Q000502:physiology*; D016615:Telomere / Q000378:metabolism
D009687:Nuclear Proteins; D004247:DNA