Risk factors and cumulative incidence of anaemia among human immunodeficiency virus-infected children in Uganda.
Anaemia has not been well characterised among HIV-infected children in sub-Saharan Africa. Baseline prevalence and cumulative incidence of anaemia (haemoglobin < 110 g/L) were 91.7% and 100% and, for moderate anaemia (haemoglobin < 90 g/L), were 35.1% and 58.4%, respectively, among 225 HIV-infected children followed from 9 to 36 months of age. Hospitalisation, suspected tuberculosis, malaria and height-for-age Z-score <-2 were significantly associated with moderate anaemia. Moderate anaemia and weight-for-height Z-score <-2 were associated with mortality. Anaemia is common and associated with increased mortality in HIV-infected children.
Clark
T D
TD
Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mmiro
F
F
Ndugwa
C
C
Perry
R T
RT
Jackson
J B
JB
Melikian
G
G
Semba
R D
RD
D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000740:Anemia / Q000150:complications* / Q000453:epidemiology; D000886:Anthropometry; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D015994:Incidence; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D016016:Proportional Hazards Models; D012307:Risk Factors; D015996:Survival Rate; D014454:Uganda / Q000453:epidemiology