The triad of bilateral retinoblastoma, dysplastic naevus syndrome and multiple cutaneous malignant melanomas: a case report and review of the literature.
We report a case of a patient with the triad of retinoblastoma, dysplastic naevus syndrome (DNS) and multiple cutaneous melanomas. The combination of retinoblastoma and DNS is a significant risk factor for the development of cutaneous melanoma. This risk extends to family members. We recommend that survivors of (inherited) retinoblastoma and their relatives are closely screened for the presence of dysplastic naevi.
Belt
P J
PJ
Department of Plastic and Reconstructive Surgery, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia. pbelt@plasticsurgery.org.au
Smithers
M
M
Elston
T
T
D000328:Adult; D004416:Dysplastic Nevus Syndrome / Q000473:pathology*; D015353:Eye Enucleation; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D019572:Retinal Neoplasms / Q000473:pathology* / Q000601:surgery; D012175:Retinoblastoma / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology*