title: Characterization and toxicity of Amanita cokeri extract.
abstract: The nonprotein amino acids 2-amino-3-cyclopropylbutanoic acid and 2-amino-5-chloro-4-pentenoic acid were isolated from the mushroom Amanita cokeri. The cyclopropyl amino acid is toxic to the fungus Cercospora kikuchii, the arthropod Oncopeltus fasciatus (milk weed bug), and the bacteria Agrobacterium tumefaciens, Erwinia amylovora, and Xanthomonas campestris. Toxicity to bacteria was reversible by addition of isoleucine to the medium. No toxicity was observed for 2-amino-5-chloro-4-pentenoic acid.
authors.affiliation: Department of Botany, North Carolina State University, Raleigh 27695, USA.
authors.forename: Dennis C
authors.initials: DC
authors.lastname: Drehmel
authors.forename: William Scott
authors.initials: WS
authors.lastname: Chilton
mesh_terms: D016960:Agrobacterium tumefaciens / Q000187:drug effects; D000545:Amanita / Q000737:chemistry*; D000613:Aminobutyrates; D002087:Butyrates / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D005658:Fungi / Q000187:drug effects; D020062:Heteroptera / Q000187:drug effects; D010421:Pentanoic Acids / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D018675:Toxicity Tests
chemical_list: C462300:2-amino-3-cyclopropylbutanoic acid; C465378:2-amino-5-chloro-4-pentenoic acid; D000613:Aminobutyrates; D002087:Butyrates; D010421:Pentanoic Acids