title: Occupational dermatitis from a one-component naphthalene type epoxy adhesive.
abstract: In an electronics plant, a new one-component naphthalene type epoxy resin was used as an adhesive for reinforcing a circuit board. The resinous part of the adhesive consisted of diglycidyl ether of bisphenol A (DGEBA) and 1,6-bis(2,3-epoxypropoxy)naphthalene type epoxy resins. The hardener was methylhexahydrophthalic anhydride (MHHPA). Of 54 workers, 15 (27.8%) were diagnosed to have work-related dermatitis but were not patch tested. Therefore, it was impossible to determine the specific agent responsible for the worker's symptoms or to distinguish between allergic and irritant contact dermatitis. They worked without protective gloves until they started to develop skin symptoms. The hands were the commonly affected region (13 out of 15 cases). The latent period of dermatitis was very short (mean 2.2 weeks). Of these, 10 cases (66.7%) received medication for dermatitis, and 9 cases (60%) were transferred to other work. The work-related skin symptoms were closely related to the specific tasks, i.e., filling dispensers with the adhesive and manual application of the adhesive to a portion of a circuit board using a dispenser. For occupational hygiene reasons, contact with epoxy resins should be minimized by taking all possible measures into use, including protective gloves. Further studies are required to clarify the allergenicity of 1,6-bis(2,3-epoxypropoxy)naphthalene, since very little is known about the mechanism through which it leads to the symptoms of dermatitis.
authors.affiliation: Matsushita Science Center of Industrial Hygiene, Kadoma, Osaka, Japan.
authors.forename: Kozo
authors.initials: K
authors.lastname: Yokota
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Johyama
authors.forename: Naomi
authors.initials: N
authors.lastname: Matsumoto
authors.forename: Kyohei
authors.initials: K
authors.lastname: Yamaguchi
mesh_terms: D000269:Adhesives / Q000009:adverse effects*; D000293:Adolescent; D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology* / Q000517:prevention & control; D009783:Dermatitis, Occupational / Q000209:etiology* / Q000517:prevention & control; D004852:Epoxy Compounds / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D016273:Occupational Exposure
chemical_list: D000269:Adhesives; D004852:Epoxy Compounds