title: [Does radiofrequency ablation of the slow pathway prevent atrial fibrillation in cases of re-entrant intranodal junctional tachycardia?].
abstract: The aim of this study was to assess the effects of ablation of the slow pathway on the eventual occurrence of atrial fibrillation (AF) in cases of intranodal junctional tachycardia (INJT). Two hundred and fifty seven patients were admitted for recurrent paroxysmal junctional tachycardia. The ages ranged from 15 to 87 years (average 54 +/- 16 years). Tachycardia was induced in all patients and the mechanism shown to be INJT in 215 patients. Twelve of these (6%) also had spontaneous paroxysmal AF. It was possible to induce INJT and AF in 23 patients during electrophysiological study (11%): of these patients, 4 had a history of AF associated with INJT. Radiofrequency ablation of the slow pathway was successfully carried out. Patients were followed up for 1 to 6 years (average 3 +/- 2 years). None were prescribed antiarrhythmic drugs. The results showed that of the 12 patients with spontaneous AF before ablation, 8 had recurrence of paroxysmal AF which required reintroduction of an antiarrhythmic treatment and a ninth patient is currently in chronic atrial fibrillation. All but one of the patients were over 65 years of age. The AF recurred 1 month to 4 years after ablation. Of the 19 patients without previous AF but with inducible AF, 2 developed spontaneous paroxysmal AF. Of the patients without previous AF and without inducible AF, 4 aged over 65 went on to develop paroxysmal AF. The authors conclude that radiofrequency ablation of the slow pathway of patients with INJT does not seem to prevent future development of AF in elderly subjects.
authors.affiliation: CHU de Brabois, rue du Morvan, 54500 Vandoeuvre-les-Nancy, France.
authors.forename: B
authors.initials: B
authors.lastname: Brembilla-Perrot
authors.forename: D
authors.initials: D
authors.lastname: Beurrier
authors.forename: P
authors.initials: P
authors.lastname: Houriez
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000209:etiology / Q000517:prevention & control*; D017115:Catheter Ablation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents
vernacular_title: L'ablation de la voie lente par radiofréquence dans les tachycardies jonctionnelles par réentrée intranodale prévient-elle le développement d'une fibrillation auriculaire?