False-positive results caused by cotton swabs in commercial Aspergillus antigen latex agglutination test.
While testing for Aspergillus spp. using a commercially available latex agglutination test on a brain biopsy wrapped in a cotton swab, false-positive results were obtained. Subsequent application of the test on lavage samples obtained using cotton and synthetic swabs resulted positive with the cotton swabs only. This suggests that epitopes cross-reactive with Aspergillus galactomannan may be present in cotton.
Dalle
F
F
Laboratoire de Parasitologie et Mycologie, Hôpital du Bocage, Dijon, France.
Lopez
J
J
Caillot
D
D
Cuisenier
B
B
Ecarnot
Laubriet A
LA
Dumont
L
L
Bonnin
A
A
D000946:Antigens, Fungal / Q000032:analysis / Q000097:blood*; D001228:Aspergillosis / Q000175:diagnosis; D001230:Aspergillus / Q000276:immunology* / Q000302:isolation & purification; D003429:Cross Reactions; D005189:False Positive Reactions; D006801:Humans; D007841:Latex Fixation Tests / Q000379:methods*; D016921:Meningitis, Fungal / Q000382:microbiology*; D016133:Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods
D000946:Antigens, Fungal