title: Malignant lesions initially subjected to short-term mammographic follow-up.
abstract: OBJECTIVE
  To determine whether systematically evaluated criteria for probably benign lesions were actually applied to lesions placed into that category.
  
  
  METHODS
  A search of the mammography database yielded 295 cases that were initially followed up with short-term interval mammography but eventually received a biopsy recommendation for the same breast. Of the 83 malignancies (81 patients) for which mammograms and pathology reports were available for review, 51 malignancies corresponded to the lesions for which short-term follow-up was recommended. Each case was retrospectively reviewed to determine whether the lesion followed up represented the subsequently diagnosed malignancy. Each lesion was characterized with appropriate Breast Imaging Reporting and Data System descriptors, based on the mammographic imaging available when short-term follow-up was first recommended. These characteristics were then used to determine if, in retrospect, the mammographic appearance met previously published criteria for probably benign lesions.
  
  
  RESULTS
  Of the 51 malignancies, 23 (45%) appeared mammographically as microcalcifications, 12 (24%) as masses, four (8%) as architectural distortion, and 12 (24%) as developing densities. None fulfilled strict criteria for a probably benign lesion when reviewed in retrospect. Forty-seven (92%) of 51 lesions had already demonstrated progression at the time of follow-up recommendation.
  
  
  CONCLUSIONS
  Short-term mammographic follow-up is often recommended for lesions that, in retrospect, do not fulfill established diagnostic criteria for probably benign lesions.
authors.affiliation: Department of Radiology, Breast Imaging Division, Duke University Medical Center, Hospital South, Rm 24254, Box 3808, Durham, NC 27710, USA. rosen017@mc.duke.edu
authors.forename: Eric L
authors.initials: EL
authors.lastname: Rosen
authors.forename: Jay A
authors.initials: JA
authors.lastname: Baker
authors.forename: Mary Scott
authors.initials: MS
authors.lastname: Soo
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors