title: [Challenges in the treatment of patients with type 2 diabetes mellitus and obesity].
abstract: The current treatment of obesity generally fails in the long term and the optimized control of diabetes represents a difficult challenge requiring a multi-disciplinary approach and a high degree of motivation by the therapeutic team, the patient and the patient's family. When diabetes is associated with obesity, quite a frequent phenomenon, the treatment of these patients represents a true clinical challenge. Although far from perfect, there are currently several therapeutic weapons available in the armoury. Non-pharmacological treatment, fundamentally a low calorie diet and its multiple variations, anti-glycaemia and anti-obesity drugs, and surgical treatment or a combination of these therapeutic strategies present various difficulties and pose several questions. The characteristics of each are analyzed with their pros and cons and their implication in weight loss, control of glycaemia, reduction in the associated cardiovascular risk factors, morbidity and mortality.
authors.affiliation: Unidad de Endocrinología y Diabetes, Servicio de Medicina Interna, Hospital Universitari Sant Joan de Reus, Sant Joan, s/n, 43201 Reus.
authors.forename: J M
authors.initials: JM
authors.lastname: Manzanares Errazu
mesh_terms: D019440:Anti-Obesity Agents / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000628:therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D009765:Obesity / Q000150:complications / Q000628:therapy*; D015431:Weight Loss
chemical_list: D019440:Anti-Obesity Agents; D007004:Hypoglycemic Agents
vernacular_title: Desafíos en el tratamiento del paciente con diabetes mellitus tipo 2 y obesidad.