title: Emergency dialysis in neonatal metabolic crises.
abstract: Metabolic crises in children with inborn errors of metabolism are caused by the accumulation of neurotoxic metabolites. Rapid elimination of these metabolites is apparently crucial to prevent irreversible neuronal damage; long-term outcome is correlated with the rate of toxin removal during the crisis. The usefulness of different blood purification techniques for removing accumulated neurotoxins is reviewed in this manuscript.
authors.affiliation: Division of Pediatric Nephrology, Children's Hospital, University of Heidelberg, Im Neuenheimer Feld 150, 69120 Heidelberg, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Daschner
authors.forename: Franz
authors.initials: F
authors.lastname: Schaefer
mesh_terms: D004632:Emergency Medical Services; D006464:Hemoperfusion; D006801:Humans; D007231:Infant, Newborn; D008661:Metabolism, Inborn Errors / Q000628:therapy*; D010530:Peritoneal Dialysis; D016060:Sorption Detoxification