title: Can traumacel be used in the treatment of chronic wounds?
abstract: Traumacel (calcium salt of oxidised cellulose) has previously only been used in the treatment of acute wounds. To assess its safety and effectiveness in the management of chronic wounds a 12-week pilot study was undertaken which involved 11 patients with 15 non-healing leg ulcers and assessed ulcer size, ulcer pain and degree of exudate. Five ulcers healed within the study period. Significant pain relief was experienced by three patients. Use of the dressing did not appear to be related to a reduction in exudate. No patients experienced sensitisation to the product or had to be withdrawn because of adverse effects. Traumacel was found to be safe in the management of chronic ulceration, and appeared to promote healing in some recalcitrant ulcers.
authors.affiliation: Department of Wound Healing, Churchill Hospital, Oxford, UK.
authors.forename: D
authors.initials: D
authors.lastname: Hofman
authors.forename: J
authors.initials: J
authors.lastname: Wilson
authors.forename: S
authors.initials: S
authors.lastname: Poore
authors.forename: G
authors.initials: G
authors.lastname: Cherry
authors.forename: T
authors.initials: T
authors.lastname: Ryan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012867:Skin / Q000293:injuries*; D014574:Uronic Acids / Q000627:therapeutic use*; D014947:Wounds and Injuries / Q000188:drug therapy*
chemical_list: D014574:Uronic Acids; C018402:traumacel