Sexual hormones in HIV-infected patients: the influence of antiretroviral therapy.
A total of 351 determinations of sexual hormones were carried out in 189 HIV-infected men in stable clinical condition. Highly active antiretroviral therapy (HAART) was associated with increased levels of both testosterone and 17beta-estradiol, but not with luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Protease inhibitors were more associated with testosterone, and non-nucleoside reverse transcriptase inhibitors with 17beta-estradiol. The values of both hormones, but not those of LH and FSH, increased with respect to pre-treatment levels in those patients who initiated HAART.
Collazos
Julio
J
Section of Infectious Diseases, Hospital de Galdakao, Vizcaya, Spain.
Martinez
Eduardo
E
Mayo
José
J
Ibarra
Sofia
S
D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects; D004958:Estradiol / Q000097:blood*; D005640:Follicle Stimulating Hormone / Q000097:blood; D015658:HIV Infections / Q000097:blood* / Q000188:drug therapy*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone