Indocyanine green angiography in patients with human T cell-lymphotropic virus type 1 uveitis.
OBJECTIVE
To determine the indocyanine green (ICG) angiographic features and to evaluate the choroidal involvement of human T-cell lymphotropic virus type 1 (HTLV-1)-associated uveitis.


METHODS
We performed ICG angiography using scanning laser ophthalmoscopy in 54 eyes of 27 patients (8 men and 19 women) diagnosed with HTLV-1 uveitis. The patient's mean age was 51.5 years with a range of 24-65 years.


RESULTS
The early phase of ICG angiography revealed ICG leakage from the choroidal vessels in the posterior pole, hyperfluorescent spots that which were not detected with fluorescein angiography, and small hypofluorescent lesions in the macula which most likely corresponded to microcirculatory disturbances in the choriocapillaris.


CONCLUSIONS
We suggest that the ICG angiographic findings reflect choroidal lesions such as infiltration with leukocytes and edema. ICG angiography may provide useful information on choroidopathy in HTLV-1 uveitis.
Sakurai
Toshiya
T
Tane Memorial Eye Hospital, Osaka, Japan. sakurai@wonder.ocn.ne.jp
Yukawa
Eiichi
E
Hara
Yoshiaki
Y
Miyata
Norio
N
Mochizuki
Manabu
M
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis; D002199:Capillary Permeability; D002829:Choroid / Q000098:blood supply / Q000473:pathology; D015862:Choroid Diseases / Q000175:diagnosis* / Q000821:virology; D004396:Coloring Agents; D004279:DNA, Viral / Q000032:analysis; D015828:Eye Infections, Viral / Q000175:diagnosis* / Q000821:virology; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D015490:HTLV-I Infections / Q000175:diagnosis* / Q000821:virology; D015368:Human T-lymphotropic virus 1 / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014605:Uveitis / Q000175:diagnosis* / Q000821:virology
D000914:Antibodies, Viral; D004396:Coloring Agents; D004279:DNA, Viral; D007208:Indocyanine Green