title: Osteoconductive coatings for total joint arthroplasty.
abstract: Osteoconductive calcium phosphate coatings for total joint arthroplasty have been in clinical use since the mid1980s. The basic principles involved and basic science evidence for the efficacy of osteoconductive coatings were examined. Hydroxyapatite coatings provide consistent and better filling with bone of the gaps and spaces around cementless joint components after surgery as compared with porous-coated implant surfaces, resulting in better implant stability. Of all the calcium phosphate coatings, hydroxyapatite coatings have had the most widespread application in hip arthroplasty. Their clinical advantages over more conventional implant surfaces are evident in primary and revision hip arthroplasties. A clinical survival rate in the author's series of 97% at a minimum of 11 years followup for the femoral component in a young active patient population (average age, 53 years) was obtained with no mechanical failures. The average polyethylene wear rate in this group was 0.129 mm/year. In a similar group of young patients with revision arthroplasty using hydroxyapatite-coated femoral components, an 11-year survival rate of 93% was obtained. Histologic analysis of specimens retrieved at autopsy confirmed the excellent bony fixation of components. Advantages of the more recent biomimetic hydroxyapatite coatings were examined.
authors.affiliation: Department of Orthopaedic Surgery, University Hospital of Maastricht, The Netherlands.
authors.forename: Rudolph G T
authors.initials: RG
authors.lastname: Geesink
mesh_terms: D019643:Arthroplasty, Replacement; D019644:Arthroplasty, Replacement, Hip; D002130:Calcium Phosphates / Q000627:therapeutic use; D020099:Coated Materials, Biocompatible; D017886:Durapatite / Q000627:therapeutic use*; D006801:Humans; D012086:Reoperation
chemical_list: D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; D017886:Durapatite; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous