title: Acute infantile haemorrhagic oedema associated with hepatitis A.
abstract: Acute infantile haemorrhagic oedema (AIHO) is characterised by purpura, ecchymosis and inflammatory oedema of the face and extremities. It is seen in children aged 4-24 months. The atiology is not known. We report a case of AIHO diagnosed by skin biopsy demonstrating leukocyte-elastic vasculitis. Laboratory studies showed positive hepatitis A IgM and IgG antibodies. The liver function tests were normal, indicating subclinical hepatitis. Cryoglobulinaemia was detected, suggesting that the disease was related to hepatitis A.
authors.affiliation: Department of Pediatrics, Zeynep Kamil Hospital, Istanbul, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Bozaykut
authors.forename: E
authors.initials: E
authors.lastname: Atay
authors.forename: Z
authors.initials: Z
authors.lastname: Atay
authors.forename: I Ozahi
authors.initials: IO
authors.lastname: Ipek
authors.forename: M
authors.initials: M
authors.lastname: Akin
authors.forename: E
authors.initials: E
authors.lastname: Dursun
mesh_terms: D000208:Acute Disease; D004487:Edema / Q000821:virology*; D005260:Female; D006506:Hepatitis A / Q000150:complications*; D006801:Humans; D007223:Infant; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000821:virology*