[Secondary prevention of coronary heart disease. Results from EuroASPIRE I and II in the region of Münster, Germany].
BACKGROUND
EuroASPIRE (European Action on Secondary Prevention through Intervention to Reduce Events) is a European multicenter study on secondary prevention in patients with coronary heart disease (CHD). The first cross-sectional survey was undertaken in 1995/96 among 3569 patients from nine countries. A second cross-sectional survey (EuroASPIRE II) was conducted in 1999/2000 among 5556 patients from 15 countries to evaluate among others whether coronary prevention had improved since the first.


METHODS
The present study was conducted in the region of Münster, Germany, as part of the EuroASPIRE study. Consecutive patients, men and women up to 70 years of age with established CHD, were identified retrospectively. A total of 392 (EuroASPIRE I) and 402 (EuroASPIRE II) patients participated. Information on cardiovascular risk factors, lifestyle and medication were obtained through medical records, interviews and examinations.


RESULTS
Both studies demonstrate a high prevalence of risk factors among CHD patients. At the time of the interview more than 60% of the patients in both surveys had two or more risk factors. The comparison of EuroASPIRE I and II reveals a substantial decrease of 20% in the prevalence of hypercholesterolemia, but an increase in the prevalence of hypertension and obesity. ACE-inhibitors, betablockers and lipid lowering drugs, especially statins, were used more frequently in EuroASPIRE II.


CONCLUSIONS
We conclude that secondary prevention of CHD in the region of Münster like in the other European study regions is less than optimal and has not substantially improved between 1996 and 2000. Potential reasons are discussed.
Heidrich
J
J
Institut für Epidemiologie und Sozialmedizin, Universitätsklinikum Münster, Germany. heidricj@uni-muenster.de
Liese
A D
AD
Kalic
M
M
Winter-Enbergs
A
A
Wellmann
J
J
Roeder
N
N
Kerber
S
S
Breithardt
G
G
Scheld
H H
HH
Kleine-Katthöfer
P
P
Keil
U
U
D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D003430:Cross-Sectional Studies; D005260:Female; D005858:Germany / Q000453:epidemiology; D006293:Health Promotion / Q000639:trends; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors
Sekundärprävention der koronaren Herzkrankheit - Ergebnisse der EuroASPIRE I- und II-Studien in der Region Münster, Germany.