title: A positive antibody screen--an encounter with the Augustine antibody.
abstract: An antibody screen is performed on the blood of patients who may require blood transfusion. If an antibody is detected, it must be identified to avoid transfusing the patient with blood that contains the corresponding antigen. Antibody screens are also performed as part of a prenatal profile to detect antibodies that may cause hemolytic disease of the newborn. In this article we report the detection of a unique antibody to an antigen of high incidence, the anti-Augustine antibody. We describe problems that may occur when this antibody is encountered, including its identification and obtaining suitable transfusion products for the patient. A brief historical review of the clinical significance of this antibody is included in the article.
authors.affiliation: Department of Pathology, Meharry Medical College, School of Medicine, Nashville, Tennessee 37208-3599, USA. robertburnette@gh.nashville.org
authors.forename: Robert E
authors.initials: RE
authors.lastname: Burnette
authors.forename: Kyle
authors.initials: K
authors.lastname: Couter
mesh_terms: D000328:Adult; D044383:Black People / Q000235:genetics; D001789:Blood Group Antigens / Q000276:immunology*; D001788:Blood Grouping and Crossmatching; D002821:Chorioamnionitis / Q000150:complications; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D005313:Fetal Death / Q000276:immunology*; D006801:Humans; D007518:Isoantibodies / Q000032:analysis*; D010641:Phenotype; D011247:Pregnancy; D065227:Transfusion Reaction
chemical_list: D001789:Blood Group Antigens; D007518:Isoantibodies