[Effect of antenatal and postnatal hypoxia on the central nervous system and its correction with peptide hormones].
Ante- and postnatal acute hypoxia significantly aggravated the postnatal development. The posthypoxic behaviour patterns included hyperactivity and training ability inhibition typical for the attention deficit syndrome. A preventive injection of peptide constellation significantly improved the posthypoxic postnatal development and abolished the most of the negative modifications of behavioural patterns.
Maslova
M V
MV
M. V. Lomonosov State University, 119899, Vorobievy Gory, Moscow, Russia.
Maklakova
A S
AS
Sokolova
N A
NA
Ahmarin
I P
IP
Goncharenko
E N
EN
Krushinskaia
Ia V
IaV
D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives / Q000494:pharmacology*; D000818:Animals; D000831:Animals, Newborn; D001288:Attention; D001522:Behavior, Animal / Q000187:drug effects*; D001921:Brain / Q000187:drug effects* / Q000254:growth & development / Q000502:physiology; D004723:Endorphins / Q000494:pharmacology*; D005260:Female; D000860:Hypoxia / Q000150:complications*; D010100:Oxygen / Q000502:physiology*; D010446:Peptide Fragments / Q000494:pharmacology*; D011247:Pregnancy; D011248:Pregnancy Complications; D011297:Prenatal Exposure Delayed Effects; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*
D004723:Endorphins; D010446:Peptide Fragments; D013973:Thyrotropin-Releasing Hormone; C041128:beta-casomorphin 7; C048487:ACTH (4-7), Pro-Gly-Pro-; D000324:Adrenocorticotropic Hormone; D010100:Oxygen
Vliianie na tsentral'nuiu nervnuiu sistemu ante- i postnatal'noĭ gipoksii i ikh korrektsiia peptidnymi gormonami.