Characteristics of a cholera outbreak, patterns of Vibrio cholerae and antibiotic susceptibility testing in rural Malawi.
The cumulative cholera attack rate in an epidemic in Malawi in 1999/2000 was 59/100,000 population, case-fatality rate 4%, and 98% of all cases presenting to health facilities required intravenous therapy. Microbiological studies showed high resistance of Vibrio cholerae to commonly recommended antibiotics, predominant Ogawa serotypes and no O139 isolates.
Zachariah
R
R
Department of Infectious Diseases, Reference Centre, Central Hospital, Rue Barble, Luxembourg. msflblantyre@malawi.net
Harries
A D
AD
Arendt
V
V
Nchingula
D
D
Chimtulo
F
F
Courteille
O
O
Kirpach
P
P
D000328:Adult; D002771:Cholera / Q000453:epidemiology*; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests / Q000379:methods; D014734:Vibrio cholerae / Q000187:drug effects