[Peripheral nerve regeneration under immunosuppression].
OBJECTIVE
To discuss peripheral nerve regeneration under immunosuppression.


METHODS
Current research trends about relationship between peripheral nerve injury and immunoreaction, the experimental result of nerve regeneration after using various immunosuppressors, and the clinical findings after human allogenous hand transplantation were extensively reviewed.


RESULTS
Peripheral nerve regeneration was accelerated under immunosuppression.


CONCLUSIONS
Peripheral nerve injury may induce immunoreaction, which inhibit nerve regeneration and function recovery.
Chen
Guo-Fen
GF
Department of Orthopedic & Trauma, Nanfang Hospital, First Millitary Medical University, Guangzhou, Guangdong, P. R. China 510515.
Gu
Li-Qiang
LQ
Pei
Guo-Xian
GX
D016572:Cyclosporine / Q000494:pharmacology; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D009416:Nerve Regeneration / Q000187:drug effects / Q000276:immunology*; D059348:Peripheral Nerve Injuries; D016559:Tacrolimus / Q000494:pharmacology
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D016559:Tacrolimus