title: [A new saikosaponin from Bupleurum chinense DC].
abstract: Bupleurum chinense DC. is a well-known and very important traditional Chinese drug. It is often used to treat common cold with fever, alternating chill and fever, feeling of fullness and oppression in the chest. A new saikosaponin was isolated from Bupleurum chinense DC. and its structure was identified as 3-O-[beta-D-glucopyranosyl (1-->3)-beta-D-fucopyranosyl]-3 beta, 16 alpha, 23, 28-tetrahydroxy-olean-11, 13 (18)-dien-30-oic acid 30-O-[xylityl(1-->1)]-beta-D-glucopyranosyl-6-ester on the basis of chemical and spectral evidence. In addition, three known saikosaponins were isolated and characterized as saikosaponin 1, 2"-O-acetyl-saikosaponin b2 and 2"-O-acetyl-saikosaponin a. All the compounds were isolated from Bupleurum chinense DC. for the first time.
authors.affiliation: School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083.
authors.forename: H
authors.initials: H
authors.lastname: Liang
authors.forename: Y
authors.initials: Y
authors.lastname: Zhao
authors.forename: Y
authors.initials: Y
authors.lastname: Bai
authors.forename: R
authors.initials: R
authors.lastname: Zhang
authors.forename: G
authors.initials: G
authors.lastname: Tu
mesh_terms: D029972:Bupleurum / Q000737:chemistry*; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives*; D012502:Sapogenins / Q000737:chemistry / Q000302:isolation & purification; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D014315:Triterpenes
chemical_list: D012502:Sapogenins; D012503:Saponins; D014315:Triterpenes; C439536:saikosaponin v-1; D009828:Oleanolic Acid; C025759:saikosaponin D