title: Group II phospholipase A2 content of tears in patients with senile cataract and primary open-angle glaucoma.
abstract: OBJECTIVE
  To determine the group II phospholipase A2 (PLA2) content of tears in patients with senile cataract or primary open-angle glaucoma (POAG) and to compare it with the PLA2 content of tears in age-matched healthy controls.
  
  
  METHODS
  The PLA2 concentration of tears was measured with time-resolved fluoroimmunoassay in 21 patients with senile cataract, 23 patients with POAG and in 40 healthy controls.
  
  
  RESULTS
  The PLA2 content of tears was 38.3+/-30.1 microg/ml in patients with senile cataract, 32.1+/-22.3 microg/ml in patients with POAG, and 36.6+/-31.1 microg/ml in healthy controls. There were no significant differences between the patient and the control groups.
  
  
  CONCLUSIONS
  We conclude that neither senile cataract nor POAG has any effect on the PLA2 content of tears.
authors.affiliation: Department of Ophthalmology, University of Turku, Finland.
authors.forename: V V
authors.initials: VV
authors.lastname: Aho
authors.forename: T J
authors.initials: TJ
authors.lastname: Nevalainen
authors.forename: V
authors.initials: V
authors.lastname: Paavilainen
authors.forename: K M
authors.initials: KM
authors.lastname: Saari
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000201:enzymology*; D005260:Female; D015200:Fluoroimmunoassay; D005902:Glaucoma, Open-Angle / Q000201:enzymology*; D054501:Group II Phospholipases A2; D006801:Humans; D008297:Male; D008875:Middle Aged; D010741:Phospholipases A / Q000378:metabolism*; D054467:Phospholipases A2; D013666:Tears / Q000201:enzymology*
chemical_list: D010741:Phospholipases A; D054501:Group II Phospholipases A2; D054467:Phospholipases A2