Patients with suspected herpes simplex encephalitis: rethinking an initial negative polymerase chain reaction result.
A statewide encephalitis diagnostic project of the California State Department of Health Services found that herpes simplex virus 1 DNA may not be detectable by molecular methods early in the clinical course of herpes simplex encephalitis.
Weil
Ana A
AA
Viral and Rickettsial Disease Laboratory, Division of Communicable Disease Control, California Department of Health Services, Richmond, CA, 94804, USA.
Glaser
Carol A
CA
Amad
Zahwa
Z
Forghani
Bagher
B
D000328:Adult; D000368:Aged; D002648:Child; D018450:Disease Progression; D020803:Encephalitis, Herpes Simplex / Q000175:diagnosis* / Q000821:virology; D005188:False Negative Reactions; D005260:Female; D018259:Herpesvirus 1, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008403:Mass Screening; D016133:Polymerase Chain Reaction / Q000379:methods