title: [Chordoma: atypical mediastinal mass. Report of a case].
abstract: Chordoma is a rare tumor which develops from remnant notochord tissue. Sacro-coccygeal and spheno-occipital localizations predominate. We report a thoracic chordoma of the fifth thoracic vertebra with mediastinal expansion in a 70-year-old woman. Pathology confirmed the diagnosis revealing a lobulated architecture, presence of physaliphorous cells and intracellular mucoid substance. Immunohistochemistry can also be very helpful in atypical cases: positive for anti-cytokeratine, antivimetin and anti-protein S100 antibodies. Spontaneous outcome is fatal. Early and complete resection is the only way to improve prognosis.
authors.affiliation: Service d'Anatomie Pathologique, Hôpital Ibn Sina, Rabat, Maroc.
authors.forename: N
authors.initials: N
authors.lastname: Mahassini
authors.forename: Z
authors.initials: Z
authors.lastname: Bernoussi
authors.forename: F
authors.initials: F
authors.lastname: Toubi
authors.forename: A
authors.initials: A
authors.lastname: Harmouch
authors.forename: J E
authors.initials: JE
authors.lastname: Bourkadi
authors.forename: F
authors.initials: F
authors.lastname: Mansouri
authors.forename: A
authors.initials: A
authors.lastname: el Hachimi
mesh_terms: D000368:Aged; D002817:Chordoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D013125:Spinal Neoplasms / Q000473:pathology*; D013904:Thoracic Vertebrae
vernacular_title: Le chordome: une masse médiastinale atypique. A propos d'un cas.