Assessing eosinophil count as a marker of immune activation among human immunodeficiency virus-infected persons in sub-Saharan Africa.
In 611 human immunodeficiency virus-infected persons who had not yet begun to receive antiretroviral therapy, we evaluated the linear association between absolute eosinophil count (as a surrogate for immune response to helminthic infection) and CD4+ T cell count, and between absolute eosinophil count and log virus load. Overall, no significant correlations were observed between eosinophil count and CD4+ T cell count, or between eosinophil count and log virus load.
Chorba
T L
TL
Projet RETRO-CI, Abidjan, Côte d'Ivoire. TLC2@cdc.gov
Nkengasong
J
J
Roels
T H
TH
Monga
B
B
Maurice
C
C
Maran
M
M
Djomand
G
G
D000328:Adult; D017954:Africa South of the Sahara / Q000453:epidemiology; D015415:Biomarkers; D015496:CD4-Positive T-Lymphocytes; D004804:Eosinophils / Q000276:immunology*; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology / Q000276:immunology*; D006373:Helminthiasis / Q000209:etiology / Q000276:immunology; D006801:Humans; D008297:Male
D015415:Biomarkers