Hemodynamic Responses to ECT After Bilateral Adrenalectomy.
The case of an elderly woman who underwent successful electroconvulsive therapy (ECT) following bilateral adrenalectomy is presented. In contrast to previous animal and human studies, sharp rises in heart rate and blood pressure were observed immediately post seizure, despite pretreatment with nifedipine. These findings indicate that the hemodynamic changes typical of ECT are not necessarily dependent upon increases in circulating epinephrine, and they confirm previous assertions that the therapeutic effect of ECT is not dependent upon intact adrenal function.
Liston
Edward H.
EH
Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, and UCLA Neuropsychiatric Institute and Hospital, Los Angeles, California, USA.
Salk
Jonathan D.
JD