Blood concentration of milnacipran in a case of a fatal automobile accident.
A fatal automobile accident involving milnacipran and ethyl alcohol is reported. The drug was identified and quantitated in blood by high-performance liquid chromatography-diode-array detection. The concentration of milnacipran in peripheral blood was 3.15 microg/mL exceeded 10.5 times the therapeutic concentration. The blood ethyl alcohol level was 1.3 g/L.
Rop
Pok P
PP
Laboratoire de Police Scientifique de Marseille, France.
Sournac
Marie H
MH
Burle
Joelle
J
Fornaris
Monique
M
Coiffait
Philippe E
PE
D000063:Accidents, Traffic; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects; D000928:Antidepressive Agents / Q000009:adverse effects / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D003521:Cyclopropanes / Q000009:adverse effects / Q000097:blood*; D004347:Drug Interactions; D000431:Ethanol / Q000009:adverse effects / Q000097:blood; D017809:Fatal Outcome; D005260:Female; D005554:Forensic Medicine / Q000379:methods; D006801:Humans; D000078764:Milnacipran; D015813:Substance Abuse Detection / Q000379:methods
D000928:Antidepressive Agents; D003521:Cyclopropanes; D000431:Ethanol; D000078764:Milnacipran