[Chordoma: atypical mediastinal mass. Report of a case].
Chordoma is a rare tumor which develops from remnant notochord tissue. Sacro-coccygeal and spheno-occipital localizations predominate. We report a thoracic chordoma of the fifth thoracic vertebra with mediastinal expansion in a 70-year-old woman. Pathology confirmed the diagnosis revealing a lobulated architecture, presence of physaliphorous cells and intracellular mucoid substance. Immunohistochemistry can also be very helpful in atypical cases: positive for anti-cytokeratine, antivimetin and anti-protein S100 antibodies. Spontaneous outcome is fatal. Early and complete resection is the only way to improve prognosis.
Mahassini
N
N
Service d'Anatomie Pathologique, Hôpital Ibn Sina, Rabat, Maroc.
Bernoussi
Z
Z
Toubi
F
F
Harmouch
A
A
Bourkadi
J E
JE
Mansouri
F
F
el Hachimi
A
A
D000368:Aged; D002817:Chordoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D013125:Spinal Neoplasms / Q000473:pathology*; D013904:Thoracic Vertebrae
Le chordome: une masse médiastinale atypique. A propos d'un cas.