title: Severe iron deficiency anemia in 42 pediatric patients.
abstract: The objective of this study was to determine the clinical and laboratory features of children with severe iron deficiency anemia. The authors retrospectively reviewed the charts of 198 children with iron deficiency anemia to ascertain cases of severe iron deficiency anemia. Forty-two children with severe iron deficient anemia were evaluated. The median age was 21 months (range, 7-240 months) at diagnosis and 27 children were 13-24 months of age. For 35 children the major source of calories was derived from cow's milk. The median hemoglobin was 4.6 g/dL (range, 2.1-6 g/dL) and the median serum ferritin was 5 microg/L (range, 1-11 microg/L). Twenty-nine received oral iron and 13 required parked red blood cell transfusions because of co-morbid cardiorespiratory distress. Severe iron deficiency anemia mostly affects children during their second year of life. Oral iron therapy is sufficient for most children, but packed red blood cell transfusions may be needed.
authors.affiliation: Department of Pediatrics, New York Medical College, Valhalla 10595, USA. claudio_sandoval@nymc.edu
authors.forename: Claudio
authors.initials: C
authors.lastname: Sandoval
authors.forename: Emily
authors.initials: E
authors.lastname: Berger
authors.forename: M Fevzi
authors.initials: MF
authors.lastname: Ozkaynak
authors.forename: Oya
authors.initials: O
authors.lastname: Tugal
authors.forename: Somasundaram
authors.initials: S
authors.lastname: Jayabose
mesh_terms: D000293:Adolescent; D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D000818:Animals; D002648:Child; D002675:Child, Preschool; D017707:Erythrocyte Transfusion; D005247:Feeding Behavior; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D007501:Iron / Q000008:administration & dosage; D008892:Milk; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D006454:Hemoglobins; D007501:Iron