Insulin lispro update.
This paper provides a review of the literature and clinical studies for insulin lispro and updated information on its advantages over regular insulin for various populations of people with diabetes.



Information was gathered from a search of Medline articles and from review of clinical studies.



Patients in various special populations using insulin lispro, with proper adjustment of basal insulin, had a greater reduction in hemoglobin A1C and fewer episodes of hypoglycemia than patients on regular insulin.



More recently published literature shows that due to its faster onset and shorter duration of action, insulin lispro is useful for not only lowering A1C values, but also for reducing hypoglycemic events in various populations with diabetes, including pediatric and pregnant patients, those with gastroparesis, and insulin pump users.
Meece
Jerry D
JD
Washington State University, College of Pharmacy, Department of Pharmacy Practice, Pullman, Washington, USA.
Campbell
R Keith
RK
Director of Clinical Services at Plaza Pharmacy and Wellness Center in Gainseville, Texas
D001786:Blood Glucose / Q000378:metabolism; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D061268:Insulin Lispro; D016239:MEDLINE
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; D061268:Insulin Lispro