[Bacteriostatic action of fluorenylidene group derivatives on mycobacteria].
Eight newly synthesized compounds--fluorenyliden derivatives have been studied for their antibacterial activity as to M. tuberculosis H37Rv and different kinds of atypical bacteria. The expressed antimicrobial activity in vitro of 5-[(fluorenyliden-3-hydrason)-aminomethyl]-thioglycolic acid (IR-95.6), lithium salt (fluorenyliden-5-aminomethyl)-thioglycolic acid (LI-15), lithium salt (fluorenyliden-9-hydraside)-thioglycolic acid (LI-75), with respect to M. tuberculosis H37Rv and considerable bacteriostatic action of all the studied substances as to M. fortuitum 23 have been established.
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AV
Lviv Scientific-Research Institute of Epidemiology and Hygiene, 12 Zelena St., Lviv, 79005, Ukraine.
D000995:Antitubercular Agents / Q000494:pharmacology*; D005449:Fluorenes / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects*
D000995:Antitubercular Agents; D005449:Fluorenes
Bakteriostatychna diia pokhidnykh fluorenilidenu na mikobakteriï.