Epidemic strains of Shigella sonnei biotype g carrying integrons.
Class 2 integrons (Tn7) were found in all randomly selected epidemic (n = 27) and preepidemic (n = 13) strains of multiresistant Shigella sonnei biotype g. A class 1 integron was also found in two epidemic strains. Gene cassettes within these integrons account for resistance to commonly used therapeutic agents.
McIver
Christopher J
CJ
Virology Division, Department of Microbiology, SEALS, Prince of Wales Hospital, Randwick, New South Wales 2031, Australia.
White
Peter A
PA
Jones
Louisa A
LA
Karagiannis
Tom
T
Harkness
Jock
J
Marriott
Deborah
D
Rawlinson
William D
WD
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004196:Disease Outbreaks; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D004405:Dysentery, Bacillary / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D019426:Integrases / Q000235:genetics*; D008297:Male; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction; D012764:Shigella sonnei / Q000145:classification* / Q000235:genetics*
D000900:Anti-Bacterial Agents; D019426:Integrases; C115006:integron integrase IntI1