Autoimmune-like pancreatitis in thymoma with myasthenia gravis.
A patient with thymoma and myasthenia gravis admitted for surgery presented increased serum levels of pancreatic amylase and lipase. Suspecting a thymoma-related autoimmune disorder, autoantibody serum titers were determined: increased autoantibody titers to acetylcholine receptors, thyroglobulin, thyroperoxidase and pancreatic insulin were detected. After thymectomy the serum levels of pancreatic enzymes decreased rapidly. Myasthenia gravis symptoms also improved. To the best of our knowledge no similar cases have been reported in the literature.
Colaut
Flavio
F
Dept. of Thoracic Surgery, City Hospital of Castelfranco Veneto, 31033 Castefranco Veneto, Treviso.
Toniolo
Lamberto
L
Sperti
Cosimo
C
Pozzobon
Maurizia
M
Scapinello
Antonio
A
Sartori
Carlo Augusto
CA
D000681:Amylases / Q000097:blood; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases; D004796:Clinical Enzyme Tests; D006801:Humans; D008049:Lipase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications*; D010179:Pancreas / Q000201:enzymology; D010195:Pancreatitis / Q000175:diagnosis / Q000276:immunology*; D013902:Radiography, Thoracic; D013934:Thymectomy; D013945:Thymoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D013953:Thymus Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D014057:Tomography, X-Ray Computed
D001323:Autoantibodies; D008049:Lipase; D000681:Amylases