Pancreatic disease in the elderly.
Pancreatic diseases occur in patients of every age. Older individuals suffer more often from gallstone related acute pancreatitis, ischaemic and idiopathic acute pancreatitis, whereas alcohol-induced acute pancreatitis occurs only in a minority of cases. Similarly, alcohol-related chronic pancreatitis in elderly people is rare and late-onset idiopathic chronic pancreatitis is the most common form of the disease. This form of chronic pancreatitis is characterized by faster progression to endocrine and exocrine pancreatic insufficiency and less severe pain compared to the clinical picture found in younger patients. Ductal pancreatic adenocarcinomas, which are responsible for more than 90% of exocrine pancreatic tumours, are typically a disease of the elderly patient. Today pancreatic resection still offers the only hope for cure and also can be performed safely in elderly patients. Age, by itself, is not a reason for withholding surgical intervention from an individual patient. Today, denial of pancreatic resection is much more likely to be based on severe co-morbidity.
Gloor
Beat
B
Department of Visceral and Transplantation Surgery, Inselspital, University of Bern, Switzerland.
Ahmed
Zulfiqar
Z
Uhl
Waldemar
W
Büchler
Markus W
MW
D000208:Acute Disease; D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D000368:Aged; D002908:Chronic Disease; D006801:Humans; D010180:Pancreatectomy; D010182:Pancreatic Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D010195:Pancreatitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy