Acute renal failure following ingestion of wild mushrooms.
We describe three cases of acute renal failure in young men who ingested wild mushrooms with the intent of producing hallucinations. Two cases remained dialysis dependent and, in these cases, renal biopsy revealed tubulointerstitial nephritis and fibrosis. Similar cases have been reported in other countries, but not in Australia. The most recognized mushroom nephrotoxin is orellanine, however the causative mushroom species and the actual toxin involved in these cases are unknown.
Mount
P
P
Department of Nephrology, Austin & Repatriation Medical Centre, Heidelberg, Victoria, Australia. Peter.Mount@armc.org.au
Harris
G
G
Sinclair
R
R
Finlay
M
M
Becker
G J
GJ
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives* / Q000506:poisoning*; D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009145:Mushroom Poisoning / Q000150:complications / Q000175:diagnosis*; D009395:Nephritis, Interstitial / Q000150:complications / Q000175:diagnosis*; D006435:Renal Dialysis / Q000379:methods; D018570:Risk Assessment; D016896:Treatment Outcome; D014739:Victoria
C030076:orellanine; D015082:2,2'-Dipyridyl