Continuous epidural infusion of 0.05% bupivacaine plus hydromorphone for labor analgesia: an observational assessment in 1830 parturients.
We evaluated a continuous epidural infusion containing bupivacaine 0.05% plus the opioid hydromorphone in 1830 women requesting pain relief during labor and delivery. The infusion provided effective analgesia with minimal adverse events for patients differing in parity and at varying stages of labor. Pain relief was maintained in most patients without the need for epidural reinforcement with more concentrated doses of local anesthetic.
Sinatra
Raymond S
RS
Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut 06520-8051, USA.
Eige
Steven
S
Chung
James H
JH
Chung
K Sam
KS
Sevarino
Ferne B
FB
Lobo
Ana
A
Fermo
Lee
L
Ocampo
Carlos A
CA
D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D004091:Hydromorphone / Q000008:administration & dosage*; D011247:Pregnancy; D011446:Prospective Studies
D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D004091:Hydromorphone; D002045:Bupivacaine