title: Gingival metastasis in lung cancer.
abstract: Gingival metastasis is an extremely rare manifestation of lung cancer, and exhibits rapid growth with various clinical symptoms. Physicians must appropriately manage patients with lung cancer who develop gingival metastasis. Clinical records of patients with lung cancer treated at the Department of Internal Medicine II, Okayama University Hospital, between 1976 and 1998 were retrospectively reviewed. The medical literature was searched by Medline to identify reports of gingival metastasis from lung cancer. Three of 729 (0.41%) lung cancer patients developed gingival metastasis in our hospital between 1976 and 1998, and 9 additional cases of this type of metastasis were found in the literature. All were male, and median age was 57.5 years (range, 47 to 70). There were no clear correlations between development of gingival metastasis and either histologic type or location of the primary lesion. Chemotherapy or radiotherapy was effective for treatment of gingival metastasis, and the quality of life was improved. However, survival after development of gingival metastasis was very short, with median survival of only 4 months.
authors.affiliation: Department of Medicine II, Okayama University Medical School, Okayama 700-8558, Japan. motoyuki@cb3.so-net.ne.jp
authors.forename: Motoyuki
authors.initials: M
authors.lastname: Tanaka
authors.forename: Akio
authors.initials: A
authors.lastname: Hiraki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ueoka
authors.forename: Akihiro
authors.initials: A
authors.lastname: Bessho
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kiura
authors.forename: Nagio
authors.initials: N
authors.lastname: Takigawa
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kodani
authors.forename: Kazuyo
authors.initials: K
authors.lastname: Miyatake
authors.forename: Noboru
authors.initials: N
authors.lastname: Hamada
authors.forename: Takumi
authors.initials: T
authors.lastname: Kishimoto
authors.forename: Mitsune
authors.initials: M
authors.lastname: Tanimoto
authors.forename: Mine
authors.initials: M
authors.lastname: Harada
mesh_terms: D000368:Aged; D005887:Gingival Neoplasms / Q000401:mortality* / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D014057:Tomography, X-Ray Computed