Protein-losing enteropathy in systemic lupus erythematosus: report of a severe, persistent case and review of pathophysiology.
Protein-losing enteropathy (PLE) is a rare manifestation of systemic lupus erythematosus (SLE). We report a severe and resistant case of PLE, discuss pathophysiology and possible role of cytokines in the disease process. We also present a review of the current literature.
Yazici
Y
Y
Hospital for Special Surgery, Weill Medical College of Cornell University, New York, USA. yaziciy@hss.edu
Erkan
D
D
Levine
D M
DM
Parker
T S
TS
Lockshin
M D
MD
D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000378:metabolism; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008775:Methylprednisolone / Q000627:therapeutic use; D011504:Protein-Losing Enteropathies / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D003520:Cyclophosphamide; D008775:Methylprednisolone