[Malignant tumor and hyperfibrinogenemia].
OBJECTIVE
To investigate the blood fibrinogen (FIB) content before and after chemotherapy or radiotherapy in 43 malignant tumor patients.


METHODS
COULTER ACL-200 automated coagulation analyzer was used in monitoring FIB in the patients.


RESULTS
The FIB content was significantly higher in malignant tumor patients than that in benign disease patients. Significant reduction was observed after treatment which became elevated again when there was recurrence or metastasis.


CONCLUSIONS
Assessment of FIB not only helps to diagnose cancers but evaluate the therapeutic effect and prognosis also.
Liu
Xiuqiao
X
Department of Clinical Laboratory, Beijing Cancer Hospital, Beijing 100036, China.
Wang
Shujuan
S
Wu
Zhenru
Z
Sun
Wei
W
Wan
Weihui
W
D014408:Biomarkers, Tumor / Q000378:metabolism*; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood* / Q000532:radiotherapy; D011379:Prognosis
D014408:Biomarkers, Tumor; D005340:Fibrinogen