title: [Influence of surgical methods on survival and recurrence of stage I endometrial carcinoma].
abstract: OBJECTIVE
  To determine the influence of different surgical procedure on post-operative survival rate and recurrence of stage I endometrial carcinoma.
  
  
  METHODS
  From 1986 to 1996, 110 patients with stage I endometrial carcinoma surgically treated in our hospital were studied retrospectively. They were divided into three groups, including total hysterectomy plus bilateral salpingo-oophorectomy (group A), radical or modified radical hysterectomy (group B) and total hysterectomy plus bilateral salpingo-oophorectomy or radical hysterectomy or modified radical hysterectomy + pelvic lymphadenectomy (group C). Survival and recurrent rates were analysed according to the follow-up data.
  
  
  RESULTS
  Five-year survival rate of the three groups are 89.5%, 90.5% and 95.1% respectively (P > 0.05). Of the 71 cases followed up for more than two years, 9 relapsed. The recurrent rates were 12.7%. Seven relapsed within three years after operation. Eight patients had local recurrence and 5 had distant metastasis. Recurrent rates of three groups are 13.9%, 9.1% and 12.5% (P > 0.05), local recurrent rates are 13.9%, 9.1% and 8.3% (P > 0.05), distant metastasis rates are 2.8%, 9.1% and 12.5% respectively (P > 0.05) with no statistical significance.
  
  
  CONCLUSIONS
  Surgical method is not the main factor influenced the survive of stage I endometrial carcinoma. Radical operation or lymphadenectomy will not increase the survival rate of stage I endometrial carcinoma significantly. The purpose of such operation is to find out the exact stage and the possible prognosis. Distant metastasis is remarkable, and should be considered in the adjuvant therapy.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors.forename: Jinsong
authors.initials: J
authors.lastname: Gao
authors.forename: Keng
authors.initials: K
authors.lastname: Shen
authors.forename: Jinghe
authors.initials: J
authors.lastname: Lang
authors.forename: Huifang
authors.initials: H
authors.lastname: Huang
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Lingya
authors.initials: L
authors.lastname: Pan
mesh_terms: D000328:Adult; D000368:Aged; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012189:Retrospective Studies; D016019:Survival Analysis; D015996:Survival Rate