title: [Mechanisms of generating calcium signals in exocrine acinar cells].
abstract: Review. Modern data about mechanisms of generation of the calcium signals in the exocrine acinar cells are presented. The mechanisms of inositol-1,4,5-trisphosphate- and Ca(2+)-induced Ca2+ release from intracellular stores of the acinar cells and mechanisms their influx from extracellular medium are described. The mechanisms which initiate Ca2+ oscillations and their role in the secretion of the fluid and enzymes by acinar cells are discussed.
authors.affiliation: Research Institute of Physiology, Taras Shevchenko Kiev University, Kiev.
authors.forename: P M
authors.initials: PM
authors.lastname: Shevchuk
authors.forename: V K
authors.initials: VK
authors.lastname: Rybal'chenko
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D020013:Calcium Signaling / Q000502:physiology*; D005088:Exocrine Glands / Q000166:cytology* / Q000378:metabolism*; D015544:Inositol 1,4,5-Trisphosphate / Q000378:metabolism; D051379:Mice
chemical_list: D015544:Inositol 1,4,5-Trisphosphate; D002118:Calcium