title: GABAergic pretectal terminals contact GABAergic interneurons in the cat dorsal lateral geniculate nucleus.
abstract: Anterograde tracing techniques combined with postembedding immunocytochemical staining were used to determine the gamma amino butyric acid (GABA) content of pretectogeniculate (PT-LGN) terminals and their postsynaptic targets. The results provide evidence that PT-LGN terminals are GABAergic and that they contact GABAergic interneurons. These results corroborate previous anatomical studies and support the idea that the PT-LGN projection functions to disinhibit thalamocortical cells in the dorsal lateral geniculate nucleus.
authors.affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville, School of Medicine, 500 S. Preston Street, Louisville, KY 40292, USA.
authors.forename: Siting
authors.initials: S
authors.lastname: Wang
authors.forename: Michael
authors.initials: M
authors.lastname: Eisenback
authors.forename: Aygul
authors.initials: A
authors.lastname: Datskovskaia
authors.forename: Martin
authors.initials: M
authors.lastname: Boyce
authors.forename: Martha E
authors.initials: ME
authors.lastname: Bickford
mesh_terms: D000818:Animals; D002415:Cats; D005260:Female; D005829:Geniculate Bodies / Q000502:physiology / Q000648:ultrastructure*; D007395:Interneurons / Q000502:physiology / Q000648:ultrastructure*; D009475:Neurons, Afferent / Q000737:chemistry / Q000502:physiology; D017729:Presynaptic Terminals / Q000502:physiology / Q000648:ultrastructure*; D013477:Superior Colliculi / Q000502:physiology / Q000648:ultrastructure*; D014795:Visual Pathways / Q000502:physiology / Q000648:ultrastructure; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
chemical_list: D005680:gamma-Aminobutyric Acid