[Molecular biological progress of hepatocyte growth factor (HGF)].
Hepatocyte growth factor (HGF) is a multifunctional growth factor which is a heterodimeric glycoprotein molecule. There are three truncated HGF variants: NK1, NK2, NK4. The structure of the promoter of HGF is very complicated, and the expression of HGF is regulated by various factors and regulatory elements. Because of the importance of HGF to human body, the genetic engineering expression and gene therapy investigation of HGF are being done.
Yu
Shui-Liang
SL
College of Life Science, Wuhan University, Wuhan 430072, China.
Yang
Fu-Hua
FH
D000818:Animals; D005786:Gene Expression Regulation; D015316:Genetic Therapy; D014644:Genetic Variation; D017228:Hepatocyte Growth Factor / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D011401:Promoter Regions, Genetic; D015202:Protein Engineering; D012326:RNA Splicing / Q000235:genetics*
D017228:Hepatocyte Growth Factor