Biomaterials to prevent nosocomial infections: is silver the gold standard?
Although many antimicrobial biomaterials have shown promising activity in vitro, few anti-infective prosthetic devices manufactured from these materials have yet achieved any degree of success in clinical trials. Controversy surrounds the exploitation of antibiotics in these materials and the microbiological methods that have been used in the clinical trials on the devices.
Stickler
David J.
DJ
Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, UK.