title: Laparoscopic adrenalectomy for pheochromocytoma.
abstract: BACKGROUND
  Laparoscopic adrenalectomy for Conn's syndrome, Cushing's disease, cortisol-producing adenomas, and nonfunctioning adenomas has been well established. This study was intended to evaluate the clinical outcomes of patients undergoing laparoscopic adrenalectomy for pheochromocytoma, and to assess the efficacy and safety of a minimally invasive approach.
  
  
  METHODS
  Data were collected prospectively on all patients undergoing laparoscopic adrenalectomy for pheochromocytoma over a 5-year period.
  
  
  RESULTS
  In this study, 39 consecutive patients underwent laparoscopic resection of a pheochromocytoma: 38 adrenal (23 left, 15 right) and 1 extraadrenal paraganglioma. There were no conversions to open surgery. The mean tumor size was 5.2 cm (range, 2-12.1 cm). Average operative time was 159 min (range, 100-265 min), and average estimated blood loss was 72 ml (range, 30-350 ml). Intraoperative hypertension (systolic blood pressure > 170 mmHg) occurred in 67% of the patients, and hypotension (systolic blood pressure < 90 mmHg) in 39% of the patients. The mean length of stay was 2.1 days (range, 1-4 days). There were three minor postoperative complications. During a mean follow-up period of 14 months, there were no mortalities or recurrences of endocrinopathy.
  
  
  CONCLUSIONS
  Laparoscopic resection of pheochromocytomas can be accomplished safely despite frequent episodes of hemodynamic variability equal to those of historic open control subjects. A short hospital stay with expedient recovery,minimal wound complications, and lack of endocrinopathy recurrence makes a minimally invasive approach the procedure of choice for the management of pheochromoctyoma.
authors.affiliation: Department of General Surgery, Carolinas Medical Center, Charlotte, NC 28232, USA.
authors.forename: K W
authors.initials: KW
authors.lastname: Kercher
authors.forename: A
authors.initials: A
authors.lastname: Park
authors.forename: B D
authors.initials: BD
authors.lastname: Matthews
authors.forename: G
authors.initials: G
authors.lastname: Rolband
authors.forename: R F
authors.initials: RF
authors.lastname: Sing
authors.forename: B T
authors.initials: BT
authors.lastname: Heniford
mesh_terms: D000315:Adrenalectomy / Q000379:methods*; D000328:Adult; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010673:Pheochromocytoma / Q000601:surgery*; D011446:Prospective Studies