abstract: From proinsulin-free insulin we obtained maximal purified insulin by means of preparative polyacrylamide electrophoresis (PADE). This substance appears in the analytical PADE as a uniform band and possesses glycine and phenylalanine as N-terminal amino acids. By use of the eviscerated rabbit as testing model, the product displays a higher hypoglycemic activity as compared with the Toronto standard.
authors.affiliation: Institut für Diabetes "Gerhardt Katsch", Bereich experimentelle Diabetesforschung, Karlsburg/Greifswald, DDR
authors.forename: H
authors.initials: H
authors.lastname: Zühlke
authors.forename: H G.
authors.initials: HG
authors.lastname: Lippmann
authors.forename: W
authors.initials: W
authors.lastname: Wilke
authors.forename: R
authors.initials: R
authors.lastname: Menzel
authors.forename: R
authors.initials: R
authors.lastname: Hildmann