title: Electrical recordings from rat cardiac muscle cells using field-effect transistors.
abstract: Extracellular electrophysiological recordings were made from cardiac cells cultured for up to seven days over microfabricated arrays of field-effect transistors. The recorded signals can be separated mainly into two types of cell transistor couplings: one that can be explained entirely by purely passive circuitry elements, and a second where voltage-gated ion channels contribute greatly to the measured extracellular signal.
authors.affiliation: Max-Planck-Institute for Polymer Research, Ackermannweg 10, D-55128 Mainz, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Sprössler
authors.forename: M
authors.initials: M
authors.lastname: Denyer
authors.forename: S
authors.initials: S
authors.lastname: Britland
authors.forename: W
authors.initials: W
authors.lastname: Knoll
authors.forename: A
authors.initials: A
authors.lastname: Offenhäusser
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002478:Cells, Cultured; D003198:Computer Simulation; D005109:Extracellular Matrix / Q000502:physiology; D015640:Ion Channel Gating / Q000502:physiology; D007473:Ion Channels / Q000502:physiology; D008954:Models, Biological; D009206:Myocardium / Q000166:cytology / Q000378:metabolism*; D051381:Rats; D012828:Silicones / Q000378:metabolism; D014173:Transistors, Electronic
chemical_list: D007473:Ion Channels; D012828:Silicones