title: [Transmaxillary approach for surgical removal of the invasive skull base tumors].
abstract: OBJECTIVE
  To investigate the capable use of transmaxillary approach for surgical removal of invasive skull base tumors, the indications and the key points of this approach.
  
  
  METHODS
  From November 1998 to July 2001, 27 consecutive patients with skull base tumor were operated through transmaxillary approach, including 6 patients with nasopharyngeal carcinoma, 5 with nasopharyngeal angiofibroma, 5 with nasopharyngeal cystadenocarcinoma, 2 with olfactory neuroblastoma, 2 with poorly differentiated carcinoma, 2 with sarcoma, 1 with maxillary carcinoma, 2 with schwannoma, and 2 with chordoma. Most of them (18/27) were recurrent tumor and 17/27 tumors involved important intracranial structures. All patients were followed up 2 - 33 months (average 16 months) and the clinical data was reviewed.
  
  
  RESULTS
  The tumors could be totally removed in all patients. There were no operative mortality and morbidity. After operation, 2 patients died of cancer recurrence in 5 and 8 months separately. One patient had metastasis to the lungs 11 months after operation. Two patients had local recurrence in 7 and 12 months postoperation seperately and live with the tumor now. The rest patients are back to their routine life.
  
  
  CONCLUSIONS
  Transmaxillary approach facilitates the surgical removal of invasive skull base tumors. The exposure is wide. The lesion as well as the important anatomy structures can be viewed directly and clearly. The tumor removal could be done more thoroughly and safely. This approach is suitable for the patients in whom tumor involves the skull base extensively and may be difficult to deal with by other approaches.
authors.affiliation: Department of Neurosurgery, China-Japan Friendship Hospital, Beijing 100029, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Guo
authors.forename: Yongfa
authors.initials: Y
authors.lastname: Qi
authors.forename: Zhen'gang
authors.initials: Z
authors.lastname: Xu
authors.forename: Yulin
authors.initials: Y
authors.lastname: Yin
authors.forename: Sixun
authors.initials: S
authors.lastname: Zhang
authors.forename: Huancong
authors.initials: H
authors.lastname: Zuo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009361:Neoplasm Invasiveness; D019635:Neurosurgical Procedures; D019292:Skull Base Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*