title: Human tolerance to acceleration after exposure to weightlessness.
abstract: The major role in the genesis of varying human tolerance to decelerations that follow weightlessness is evidently played by hypodynamic and hydrostatic factors. Long disuse of compensatory antigravity mechanisms in weightlessness may bring about their deconditioning and reduction of their functional capabilities, and may finally affect general tolerance of crewmembers to decelerations. Laboratory experiments demonstrated changes in the human tolerance to Gx accelerations of varying duration (from 3 to 100 days) and tested the efficacy of different countermeasures. A decrease in the human tolerance to +Gx is on the average -2.0g. It should be noted that an elongation of simulated weightlessness (from 7 to 100 days) caused no further decrease in the +Gx tolerance. Our investigations helped to assess the threshold of human tolerance to accelerations after an exposure to simulated weightlessness and to delineate the value of real risk. The tolerance limit to +Gx accelerations which followed simulated weightlessness of the above duration ranged from 9.5 to 13.0g, averaging 11.6 +/- 1.6g. The information on the tolerance of Soviet and American astronauts to decelerations shown during re-entry in real space flights give support to the laboratory results and predictions.
authors.affiliation: Institute of Medical and Biological Problems, Moscow, USSR.
authors.forename: A R
authors.initials: AR
authors.lastname: Kotovskaya
mesh_terms: D000054:Acceleration; D000222:Adaptation, Physiological; D001794:Blood Pressure / Q000502:physiology; D018493:Cardiovascular Deconditioning / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D018471:Hypergravity; D009133:Muscular Atrophy / Q000503:physiopathology; D013026:Space Flight; D014893:Weightlessness; D018474:Weightlessness Simulation