Energy dependent interaction of oligomycin and dicyclo hexylcarbodiimide with the mitochondrial membrane.
The characteristics of the oligomycin and DCCD inhibitions of energy linked reactions supported by ATP, indicate that the inhibition is increased by the presence of ATP. It is proposed that such an effect can be attributed to an energy linked change in the structure of some component of the ATPase, facilitating oligomycin interaction with the membrane.
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Istituto di Patologia Generale, Università di Padova, Padova, Italy
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