Central venous catheter-related Rhodotorula rubra fungemia.
With the increased use of indwelling central venous catheters, increasing numbers of cases of Rhodotorula fungemia have been observed in patients with neoplasia and neutropenia. In most patients with catheter-related Rhodotorula fungemia, the condition has been treated with broadspectrum antibiotics. We report two cases of central venous catheter-related Rhodotorula rubra fungemia that occurred in patients with acute myeloblastic leukemia. Both patients were in a state of neutropenia. One patient was treated with amphotericin B and his central venous catheter was removed, but he died of Klebsiella pneumoniae bacteremia. The other patient was treated with amphotericin B and discharged, with a central venous catheter, after recovery from neutropenia. Although the management of catheter-related Rhodotorula fungemia infections remains controversial, resolution of the underlying disease is more important than catheter removal for recovery from Rhodotorula rubra fungemia.
Chung
Jin-Won
JW
Division of Infectious Diseases, Asan Medical Center, Poongnap-dong, Songpa-gu, Seoul 138-736, Korea. yskim@amc.seoul.kr
Kim
Baek-Nam
BN
Kim
Yang Soo
YS
D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012248:Rhodotorula / Q000302:isolation & purification*
D000666:Amphotericin B