Radiation-induced meningiomas.
High dose radiation-induced meningiomas are a rare, severe and late complication of craniospinal radiotherapy for brain tumors. Radiation-induced meningiomas are, according to the literature, several times more frequent than radiogenic gliomas and sarcomas. It is suggested that every new case of radiogenic meningioma has to be reported to elucidate this particular pathologic entity with its many grey areas. In addition to high dose radiation-induced meningiomas, intracranial meningiomas were observed in patients who underwent low-dose radiation for tinea capitis in childhood, applied en mass to immigrants coming to Israel from the North Africa and the Middle East during the 1950. Authors summarize the data on radiogenic meningiomas from the literature and, as the previous radiotherapy may confer a low, but life-long risk for meningioma occurrence, they suggest that surveillance MRI after high dose cerebrospinal radiotherapy should be extended to several (3-5) decades after radiotherapy.
Boljesíkova
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Department of Radiotherapy, St Elisabeth Cancer Institute, Bratislava, Slovak Republic. ebolijasi@ousa.sk
Chorvath
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D002493:Central Nervous System Diseases / Q000150:complications / Q000532:radiotherapy; D006801:Humans; D008579:Meningioma / Q000150:complications / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*