Hyponatremia associated with sertraline and fluoxetine: a case report.
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a rare but serious adverse effect of the selective serotonin reuptake inhibitors (SSRIs). Although many case reports describe this association, few report the effect of rechallenge with another SSRI. We present a case of an elderly patient who developed hyponatremia with sertraline and SIADH when rechallenged with fluoxetine.
Raphael
Kalani
K
University of Hawaii, John A. Burns School of Medicine, USA.
Tokeshi
Jinichi
J
D000368:Aged; D000369:Aged, 80 and over; D000928:Antidepressive Agents / Q000009:adverse effects*; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects; D003866:Depressive Disorder / Q000188:drug therapy; D005473:Fluoxetine / Q000009:adverse effects*; D006801:Humans; D007010:Hyponatremia / Q000209:etiology* / Q000628:therapy; D007177:Inappropriate ADH Syndrome / Q000209:etiology* / Q000628:therapy; D008297:Male; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects*; D020280:Sertraline / Q000009:adverse effects*; D016896:Treatment Outcome
D000928:Antidepressive Agents; D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline