title: Central venous catheter-related Rhodotorula rubra fungemia.
abstract: With the increased use of indwelling central venous catheters, increasing numbers of cases of Rhodotorula fungemia have been observed in patients with neoplasia and neutropenia. In most patients with catheter-related Rhodotorula fungemia, the condition has been treated with broadspectrum antibiotics. We report two cases of central venous catheter-related Rhodotorula rubra fungemia that occurred in patients with acute myeloblastic leukemia. Both patients were in a state of neutropenia. One patient was treated with amphotericin B and his central venous catheter was removed, but he died of Klebsiella pneumoniae bacteremia. The other patient was treated with amphotericin B and discharged, with a central venous catheter, after recovery from neutropenia. Although the management of catheter-related Rhodotorula fungemia infections remains controversial, resolution of the underlying disease is more important than catheter removal for recovery from Rhodotorula rubra fungemia.
authors.affiliation: Division of Infectious Diseases, Asan Medical Center, Poongnap-dong, Songpa-gu, Seoul 138-736, Korea. yskim@amc.seoul.kr
authors.forename: Jin-Won
authors.initials: JW
authors.lastname: Chung
authors.forename: Baek-Nam
authors.initials: BN
authors.lastname: Kim
authors.forename: Yang Soo
authors.initials: YS
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012248:Rhodotorula / Q000302:isolation & purification*
chemical_list: D000666:Amphotericin B