title: Bilateral peripheral corneal infiltrates after simultaneous myopic laser in situ keratomileusis.
abstract: We describe a patient with multiple superior corneal infiltrates in both eyes, separated from the limbus by an intervening clear zone, that appeared 1 day after uneventful laser in situ keratomileusis. The overlying epithelium was intact, and the flap and interface were uninvolved. Based on these features, a clinical diagnosis of sterile corneal infiltrates was made and the eyes were treated with topical antibiotics and steroids. The infiltrates resolved during the ensuing weeks without corneal scarring. Good visual acuity was maintained. Recognition of this benign complication is important because aggressive corneal scrapings are not required. The infiltrates appear to be immunogenic in origin, although the exact etiopathogenesis is not clear.
authors.affiliation: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, University Eye Center, Hong Kong Eye Hospital, Hong Kong, China.
authors.forename: Edward Y W
authors.initials: EY
authors.lastname: Yu
authors.forename: Srinivas K
authors.initials: SK
authors.lastname: Rao
authors.forename: Arthur C K
authors.initials: AC
authors.lastname: Cheng
authors.forename: Ricky W K
authors.initials: RW
authors.lastname: Law
authors.forename: Alfred T S
authors.initials: AT
authors.lastname: Leung
authors.forename: Dennis S C
authors.initials: DS
authors.lastname: Lam
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003316:Corneal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003319:Corneal Stroma / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D004359:Drug Therapy, Combination; D005469:Fluorometholone / Q000627:therapeutic use; D005938:Glucocorticoids; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D009184:Mydriatics / Q000627:therapeutic use; D009216:Myopia / Q000601:surgery*; D015242:Ofloxacin / Q000627:therapeutic use; D010656:Phenylephrine / Q000627:therapeutic use; D014331:Tropicamide / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D009184:Mydriatics; D010656:Phenylephrine; D015242:Ofloxacin; D014331:Tropicamide; D005469:Fluorometholone