title: Alzheimer's vaccine: a cure as dangerous as the disease?
abstract: Studies in transgenic mouse models of Alzheimer's disease suggested the potential for a vaccine development. However, some patients in the human clinical trials developed symptoms of brain inflammation, demonstrating the high risk of a deliberately induced auto-immune response.
authors.affiliation: Neuroimmunological Cell Biology Unit, Interdisciplinary Center for Clinical Research (IZKF), University of Leipzig, Federal Republic of Germany. mueg@medizin.uni-leipzig.de
authors.forename: G
authors.initials: G
authors.lastname: Münch
authors.forename: S R
authors.initials: SR
authors.lastname: Robinson
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects / Q000627:therapeutic use; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000276:immunology; D023582:Alzheimer Vaccines / Q000009:adverse effects* / Q000627:therapeutic use; D016229:Amyloid beta-Peptides / Q000009:adverse effects / Q000627:therapeutic use; D000818:Animals; D004660:Encephalitis / Q000139:chemically induced*; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic / Q000235:genetics / Q000276:immunology
chemical_list: C437846:AN-1792; D000276:Adjuvants, Immunologic; D023582:Alzheimer Vaccines; D016229:Amyloid beta-Peptides