Pressure sensation by an anterior pagoda neuron population distributed in multiple ganglia in the leech, Whitmania pigra.
Sensory processing of pressure signals in the central nervous system of the leech, Whitmania pigra, was studied through the interaction between pressure sensory neurons and anterior pagoda neurons. The responses of anterior pagoda neurons to one pulse or a train of pulses in pressure sensory neurons were characterized by the latency and amplitude of excitatory postsynaptic potentials. Here we show that each pressure sensory neuron is able to activate all the anterior pagoda neurons throughout the leech central nervous system. The response patterns of all anterior pagoda neurons were appropriate to the pressure location: in the longitudinal direction the anterior pagoda neuron further away from the pressure sensory neuron had a smaller response with longer latency; inside each ganglion, the anterior pagoda neuron on the contralateral side had a larger response with shorter latency than that on the ipsilateral side. All anterior pagoda neurons excited by pressure sensory neurons comprised a parallel system in which each anterior pagoda neuron was independent from the others. The location information of pressure stimuli was represented through the response of all 40 anterior pagoda neurons covering the whole leech body with a specific pattern of latency and amplitude.
Jin
Wenjun
W
Department of Physiology and Biophysics, College of Life Sciences, Peking University, Beijing 100871, PR China.
Zhang
Ren-Ji
RJ
D000818:Animals; D005724:Ganglia / Q000502:physiology*; D007865:Leeches / Q000502:physiology*; D008564:Membrane Potentials / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D011312:Pressure; D012677:Sensation / Q000502:physiology*