title: Evaluation of glucoiberin reference material from Iberis amara by spectroscopic fingerprinting.
abstract: Increasing worldwide regulations require increased efforts toward validation of analytical and pharmacological reference materials. A detailed survey of glucoiberin, a prototype lead constituent of therapeutic value, using 1D/2D NMR, MS, and X-ray spectroscopy provided precise phytochemical data for structure assignment. Quantitative reference validation was achieved by the recently proposed qNMR method.
authors.affiliation: Zentralinstitut Arzneimittelforschung (ZA) GmbH, Kranzweiherweg 10, 53489 Sinzig, Germany.
authors.forename: Birgit
authors.initials: B
authors.lastname: Jaki
authors.forename: Otto
authors.initials: O
authors.lastname: Sticher
authors.forename: Markus
authors.initials: M
authors.lastname: Veit
authors.forename: Roland
authors.initials: R
authors.lastname: Fröhlich
authors.forename: Guido F
authors.initials: GF
authors.lastname: Pauli
mesh_terms: D002794:Choline / Q000031:analogs & derivatives* / Q000737:chemistry; D018360:Crystallography, X-Ray; D005961:Glucosinolates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology / Q000592:standards; D013058:Mass Spectrometry; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D012015:Reference Standards; D012639:Seeds / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D005961:Glucosinolates; C457341:glucoiberin; C010330:sinigrin; D002794:Choline; C003313:sinalbin