title: Wavefront analysis of higher-order aberrations in patients with cataract.
abstract: OBJECTIVE
  To determine local refractive changes and higher-order aberrations in patients with nuclear or cortical cataract.
  
  
  METHODS
  Osaka University Medical School, Osaka, Japan.
  
  
  METHODS
  Wavefront analysis of both ocular and corneal aberrations was performed with the Hartmann-Shack aberrometer in 2 patients, a 22-year-old woman with bilateral developmental nuclear cataract and a 68-year-old woman with mild bilateral cortical cataract.
  
  
  RESULTS
  Case 1 showed a delay in the wavefront that caused a myopic shift in the central pupillary area in both eyes, associated with the nuclear cataract. The spherical-like aberration (right eye, 36%; left eye, 21%) was greater than the coma-like aberration in both eyes. Case 2 showed an advancement of the wavefront that caused a hyperopic shift, especially in the lower temporal pupillary area, that was associated with the cortical cataract. The coma-like aberration (right eye, 63%; left eye, 52%) was greater than the spherical-like aberration in both eyes. The polarity of the third-order spherical aberration was negative in Case 1 and positive in Case 2. Corneal higher-order aberrations were small and had a different distribution than ocular higher-order aberrations in both patients.
  
  
  CONCLUSIONS
  The Hartmann-Shack aberrometer was useful in detecting local refractive changes and higher-order aberrations in patients with mild cataract. The polarity and the absolute value of ocular higher-order aberrations may be useful parameters to characterize eyes with cataract.
authors.affiliation: Department of Applied Medical Engineering, Osaka University Medical School, Osaka, Japan.
authors.forename: Teruhito
authors.initials: T
authors.lastname: Kuroda
authors.forename: Takashi
authors.initials: T
authors.lastname: Fujikado
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Maeda
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Oshika
authors.forename: Yoko
authors.initials: Y
authors.lastname: Hirohara
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Mihashi
mesh_terms: D000328:Adult; D000368:Aged; D002386:Cataract / Q000150:complications / Q000175:diagnosis*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000175:diagnosis* / Q000209:etiology; D007904:Lens Cortex, Crystalline / Q000473:pathology*; D007907:Lens Nucleus, Crystalline / Q000473:pathology*; D009216:Myopia / Q000175:diagnosis* / Q000209:etiology