title: The safety of carotid endarterectomy in patients with preoperative renal dysfunction.
abstract: Recent published data suggest that performing carotid endarterectomy (CEA) in patients with renal dysfunction is associated with a prohibitively high perioperative stroke and death rate. On the basis of our experience, we hypothesized that CEA is a safe procedure in patients with renal insufficiency. A retrospective review of one surgeon's CEA experience from 1988 to 1998 was performed. A total of 398 procedures performed on 370 patients were reviewed for patient demographics and adverse events in the 30-day perioperative period. Risk factors, indications for procedure, and degree of stenosis, as well as intraoperative use of shunts, patch angioplasty, drains, completion angiography, and EEG monitoring were compared. Patients were categorized by preoperative creatinine (Cr) levels as normal (Cr <or= 1.5) or abnormal (Cr > 1.5). All data were subjected to statistical analysis. Our results showed that CEA can be performed safely in patients with renal dysfunction with no increase in perioperative stroke or death rate. Performing CEA in patients with renal insufficiency does require preoperative cardiac evaluation and close cardiac monitoring, as there appears to be an increased rate of myocardial infarction in our series.
authors.affiliation: Division of Vascular Surgery, Gonda (Goldschmied) Vascular Center, UCLA Center for Health Sciences, University of California Los Angeles School of Medicine, Los Angeles, CA 90095-6904, USA.
authors.forename: Todd
authors.initials: T
authors.lastname: Reil
authors.forename: Shant
authors.initials: S
authors.lastname: Shekherdimian
authors.forename: Pamela
authors.initials: P
authors.lastname: Golchet
authors.forename: Wesley
authors.initials: W
authors.lastname: Moore
mesh_terms: D000368:Aged; D002340:Carotid Artery Diseases / Q000150:complications / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000401:mortality*; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology*; D011183:Postoperative Complications / Q000453:epidemiology* / Q000401:mortality; D051437:Renal Insufficiency / Q000150:complications*; D012131:Respiratory Insufficiency / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000209:etiology*