title: Oxidative stress during vitamin A-induced abnormal tail regeneration in the tadpoles of Polypedates maculatus.
abstract: Vitamin A and its derivatives inhibit normal tail regeneration in amphibians. The most remarkable effect is the development of limbs at the cut end of the tail in anurans. Prior to ectopic limb development, there is an abnormal tail regeneration in the treated tadpoles. The purpose of the present study was to compare oxidative stress condition in the regenerated tail of normal and vitamin A (10I U/ml, 72 h) treated tadpoles. The present findings show a hyper-oxidative stress condition in the regenerated tail of the vitamin A-treated tadpoles of the Indian jumping frog, Polypedates maculatus (Anura: Rhacophoridae).
authors.affiliation: Developmental Biology Laboratory, Department of Zoology, Utkal University, -751004, Bhubaneswar, India. mahap_pk@sify.com
authors.forename: Pravati Kumari
authors.initials: PK
authors.lastname: Mahapatra
authors.forename: Priyambada
authors.initials: P
authors.lastname: Mohanty-Hejmadi
authors.forename: Gagan B N
authors.initials: GB
authors.lastname: Chainy
mesh_terms: D000818:Animals; D001001:Anura / Q000502:physiology*; D002374:Catalase / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D005978:Glutathione / Q000378:metabolism; D006614:Hindlimb / Q000002:abnormalities; D006861:Hydrogen Peroxide / Q000378:metabolism; D007814:Larva / Q000166:cytology / Q000502:physiology; D015227:Lipid Peroxidation; D018384:Oxidative Stress; D012038:Regeneration / Q000187:drug effects* / Q000502:physiology; D013482:Superoxide Dismutase / Q000378:metabolism; D013623:Tail / Q000187:drug effects* / Q000502:physiology; D014801:Vitamin A / Q000494:pharmacology*
chemical_list: D014801:Vitamin A; D006861:Hydrogen Peroxide; D002374:Catalase; D013482:Superoxide Dismutase; D005978:Glutathione