title: Comparative, clinico-epidemiologic study of Schistosoma mansoni infections in travellers and immigrants in Spain.
abstract: The study presented here aimed to contrast the marked clinical differences in the presentation of Schistosoma mansoni-induced infection between immigrants and travellers entering Spain from endemic regions, and to elucidate the therapeutic implications of these infections. A total of 200 African immigrants and 80 travellers with schistosomiasis were included in the study. Among the immigrants, 25 patients were diagnosed with Schistosoma mansoni infection; 15 presented with nonspecific symptoms, and 10 were asymptomatic. Hepatosplenomegaly was observed in nine. Among the travellers, 14 were diagnosed with Schistosoma mansoni infection; four were asymptomatic, four had Katayama syndrome, four had diarrhoea, and two had prostatitis. All of the patients were treated with praziquantel. Patients diagnosed with Katayama syndrome received praziquantel and dexamethasone for 3 days, with the praziquantel treatment being repeated at 3-4 weeks. The significant differences observed in the clinical presentation of Schistosoma mansoni-induced infection, indicate that a well-differentiated therapeutic strategy is required when this infection is diagnosed in a non-immune (traveller) or a semi-immune (immigrant) patient.
authors.affiliation: International Health Commission, Societat Catalana de Medicina Familiar i Comunitària, Area bàsica de Salut el Clot, Institut Català de la Salut, c/Bilbao 305, 08026 Barcelona, Spain. 27543lvs@comb.es
authors.forename: C
authors.initials: C
authors.lastname: Roca
authors.forename: X
authors.initials: X
authors.lastname: Balanzó
authors.forename: J
authors.initials: J
authors.lastname: Gascón
authors.forename: J L
authors.initials: JL
authors.lastname: Fernández-Roure
authors.forename: T
authors.initials: T
authors.lastname: Vinuesa
authors.forename: M E
authors.initials: ME
authors.lastname: Valls
authors.forename: G
authors.initials: G
authors.lastname: Sauca
authors.forename: M
authors.initials: M
authors.lastname: Corachán
mesh_terms: D000328:Adult; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D004641:Emigration and Immigration; D006801:Humans; D011223:Praziquantel / Q000627:therapeutic use; D012550:Schistosoma mansoni / Q000302:isolation & purification*; D012552:Schistosomiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D013030:Spain / Q000453:epidemiology; D014195:Travel
chemical_list: D000871:Anthelmintics; D011223:Praziquantel