title: Outcome of gastric bypass patients.
abstract: BACKGROUND
  The authors analyzed previously studied outcomes of Roux-en-Y gastric bypass (RYGBP), examined pre-surgical factors of post-surgical outcomes, and examined some of the psychosocial benefits.
  
  
  METHODS
  A retrospective chart review was conducted of 138 patients who underwent RYGBP between 1997 and 2000. Pre-surgical BMI, cholesterol, blood pressure, creatinine, number of antidepressant/glycemic drugs, and hemoglobin were recorded. Post-surgical follow-up was reviewed to examine changes.
  
  
  RESULTS
  Statistically significant changes were found in BMI, hypertension, cholesterol and glycemic control. Surgery was found to reduce creatinine from a pre-surgery average of 1.14 to 1.01 (n = 11, p = .0015)). Patients with early post-operative complications (defined as length of stay > 6 days or re-hospitalization within 1 month following surgery) had an average BMI of 57.58 (n = 23) vs a BMI of 49.9 (n = 103) in those who did not experience any complications (p = 0.0004). There was a statistically significant decrease in the rate of anti-depressant use following surgery. 49 patients were on antidepressants before surgery vs 38 following surgery (p = .0016).
  
  
  CONCLUSIONS
  RYGBP significantly improves hypertension, hyperlipidemia and type II diabetes, and may also improve kidney function. Patients with higher pre-surgical BMIs are at greater risk for post-surgical complications. Postoperative antidepressant use appears to decrease.
authors.affiliation: University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Holzwarth
authors.forename: Darren
authors.initials: D
authors.lastname: Huber
authors.forename: Alicia
authors.initials: A
authors.lastname: Majkrzak
authors.forename: Basir
authors.initials: B
authors.lastname: Tareen
mesh_terms: D000293:Adolescent; D000328:Adult; D000713:Anastomosis, Roux-en-Y / Q000009:adverse effects / Q000523:psychology; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000523:psychology / Q000601:surgery*; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects* / Q000523:psychology*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000523:psychology / Q000601:surgery*; D006973:Hypertension / Q000150:complications / Q000523:psychology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000523:psychology* / Q000601:surgery*; D017063:Outcome Assessment, Health Care; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D015431:Weight Loss
chemical_list: D006454:Hemoglobins