title: Dopamine effects on pulmonary artery pressure in hypotensive preterm infants with patent ductus arteriosus.
abstract: We investigated the effects of dopamine on pulmonary artery pressure in 18 ventilated hypotensive preterm neonates by using the flow characteristics of the ductal shunt. Dopamine has variable effects on pulmonary/systemic mean arterial pressure ratio with half the neonates showing an increase in pulmonary pressure relative to systemic pressure.
authors.affiliation: Pediatric and Neonatal Critical Care Division, University Hospital of Nantes, France.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Liet
authors.forename: Cécile
authors.initials: C
authors.lastname: Boscher
authors.forename: Christèle
authors.initials: C
authors.lastname: Gras-Leguen
authors.forename: Véronique
authors.initials: V
authors.lastname: Gournay
authors.forename: Thierry
authors.initials: T
authors.lastname: Debillon
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Rozé
mesh_terms: D001794:Blood Pressure / Q000187:drug effects*; D004298:Dopamine / Q000494:pharmacology*; D004374:Ductus Arteriosus, Patent / Q000503:physiopathology*; D015150:Echocardiography, Doppler; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000188:drug therapy* / Q000503:physiopathology; D007231:Infant, Newborn; D007234:Infant, Premature; D011446:Prospective Studies; D011651:Pulmonary Artery / Q000187:drug effects*; D014662:Vasoconstrictor Agents / Q000494:pharmacology*
chemical_list: D014662:Vasoconstrictor Agents; D004298:Dopamine