Posthypoxic myoclonus animal models.
The animal model presented here resembles several of the key features of human myoclonus. Further study of the neuropathology and pharmacology of this animal model will hopefully increase our knowledge of the brain structures and systems affected in this disease and permit testing of therapeutic agents for the significant number of patients who do not respond to current treatments.
Truong
Daniel D
DD
Parkinson's and Movement Disorder Institute, Fountain Valley, California, USA.
Kirby
Michael
M
Kanthasamy
Anumantha
A
Matsumoto
Rae R
RR
D000161:Acoustic Stimulation; D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D004195:Disease Models, Animal; D004569:Electroencephalography; D000860:Hypoxia / Q000150:complications*; D009207:Myoclonus / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology / Q000523:psychology; D051381:Rats