title: Benign lymphoid infiltrate of the iris simulating a malignant melanoma.
abstract: OBJECTIVE
  To report a clinicopathologic correlation of an unusual benign lymphocytic iris mass in a patient who had no systemic lymphoproliferative disease.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A 49-year-old man developed a circumscribed, tan lesion in his left iris. The lesion was suspected clinically to be an atypical iris melanoma. Histopathologic studies of the resected mass revealed a solid tumor that was comprised of lymphocytes and histiocytes. Immunohistochemical studies identified that most of the cells were T lymphocytes. The histopathologic diagnosis was atypical lymphoid infiltrate. Workup for systemic lymphoma and Epstein-Barr virus infection was negative.
  
  
  CONCLUSIONS
  Lymphoid infiltrate can manifest as a solitary mass that can simulate an iris melanoma.
authors.affiliation: Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Mithlesh C
authors.initials: MC
authors.lastname: Sharma
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
authors.forename: Ralph C
authors.initials: RC
authors.lastname: Eagle
authors.forename: Hakan
authors.initials: H
authors.lastname: Demirci
authors.forename: Lee
authors.initials: L
authors.lastname: Wiley
mesh_terms: D003937:Diagnosis, Differential; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D015811:Iris Neoplasms / Q000175:diagnosis*; D008223:Lymphoma / Q000175:diagnosis*; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D008875:Middle Aged; D013601:T-Lymphocytes / Q000473:pathology