title: Gastric carcinoma resembling submucosal tumor.
abstract: Acase of stomach carcinoma showing features of submucosal tumor is reported. The patient was a 50-year-old man presenting with hematemesis. Endoscopic examination was performed and revealed a submucosal tumor-like lesion with central ulceration in the fornix of the stomach. The biopsy specimen from this lesion showed poorly differentiated adenocarcinoma, and surgery was performed. The tumor, measuring 3.5 x 2.7 cm in size, invaded to the muscularis propria with proliferation of the interstitial connective tissue and lymphoid follicles consisting mainly of B lymphocytes in the submucosal layer. In situ hybridization of tumor tissue for Epstein-Barr virus (EBV)-encoded small RNA1 as target revealed negative results. In stomach carcinoma simulating submucosal tumor, as in this patient, preoperative diagnosis is important to plan treatment strategies.
authors.affiliation: Department of Surgery, Fujinomiya City General Hospital, 3-1 Nishikicho, Fujinomiya, Shizuoka 418-0076, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Umehara
authors.forename: Taizo
authors.initials: T
authors.lastname: Kimura
authors.forename: Tadatoshi
authors.initials: T
authors.lastname: Okubo
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Sano
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Nakai
authors.forename: Satoshi
authors.initials: S
authors.lastname: Oi
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Higashi
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Funai