An elderly patient with DCIS of the breast effectively treated with toremifene alone.
An elderly patient with breast cancer received toremifene monotherapy for one year, and about 60% tumor remission rate was obtained. Since viability of the residual tumor was suspected on ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI), lumpectomy was performed under local anesthesia. The histopathological diagnosis was ductal carcinoma in situ (DCIS). The patient did not undergo axillary lymph node dissection or systemic chemotherapy. The patient is alive without disease under postoperative radiotherapy and toremifene treatment. Toremifene monotherapy and/or preoperative adjuvant therapy with toremifene alone may be useful methods for elderly patients with breast cancer considering the patients' quality of life.
Hamada
Norihiko
N
Department of Radiology, Hosogi Hospital, Kochi 780-8535, Japan.
Ogawa
Yasuhiro
Y
Nishioka
Akihito
A
Kariya
Shinji
S
Terashima
Masako
M
Yoshida
Shoji
S
Tanaka
Yohsuke
Y
Inomata
Taisuke
T
D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011788:Quality of Life; D014057:Tomography, X-Ray Computed; D017312:Toremifene / Q000627:therapeutic use*; D016896:Treatment Outcome; D014463:Ultrasonography
D017312:Toremifene