title: Integrating functions at the kinetochore.
abstract: Kinetochore components have catalytic as well as structural activities. New evidence illustrates how these proteins integrate spindle morphogenesis with regulation of the timing and accuracy of chromosome segregation.
authors.affiliation: Department of Biology and Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
authors.forename: Soni L
authors.initials: SL
authors.lastname: Shimoda
authors.forename: Frank
authors.initials: F
authors.lastname: Solomon
mesh_terms: D000705:Anaphase / Q000502:physiology; D000818:Animals; D020090:Chromosome Segregation / Q000502:physiology; D006801:Humans; D018386:Kinetochores / Q000502:physiology*; D046911:Macromolecular Substances; D008870:Microtubules / Q000502:physiology; D008938:Mitosis / Q000502:physiology*; D008941:Spindle Apparatus / Q000502:physiology*
chemical_list: D046911:Macromolecular Substances