Improved executive functioning following repetitive transcranial magnetic stimulation.
The cognitive effects of active and sham repetitive transcranial magnetic stimulation (rTMS) were examined in 19 middle-aged and elderly patients with refractory depression. Patients received either active (n = 9) or sham (n = 10) rTMS targeted at the anterior portion of the left middle frontal gyrus. Patients in the active rTMS group improved significantly on a test of cognitive flexibility and conceptual tracking (Trail Making Test-B).
Moser
D J
DJ
Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA 52240, USA. David.Moser@uiowa.edu
Jorge
R E
RE
Manes
F
F
Paradiso
S
S
Benjamin
M L
ML
Robinson
R G
RG
D000368:Aged; D001921:Brain / Q000473:pathology; D003866:Depressive Disorder / Q000473:pathology / Q000523:psychology* / Q000628:therapy*; D004574:Electromagnetic Fields; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology*