title: Increasing incidence of resistance to antimicrobials in Sidamo.
abstract: This study compares the prevailing sensitivity of bacterial isolates to common antimicrobials during the two-year 1985-87, 1990-92 and 1996-97 periods at Yirga Alem Hospital in southern Ethiopia. All specimens were from patients attending the hospital. We studied 1371 specimens, 337,671 and 363 specimens from the periods 1985-87, 1990-92 and 1996-97, respectively. The study confirms earlier observations of widespread resistance to commonly used antibiotics. Significant increases in the rate of resistance during this thirteen-year period were observed for Neisseria gonorrhoea against erythromycin, trimethoprim-sulphamethoxazole and tetracyclines, for Escherichia coli against ampicillin and trimethoprim-sulphamethoxazole and for Proteus species against ampicillin. We observed a decrease in the prevalence of resistance for Klebsiella and Proteus species against chloramphenicol.
authors.affiliation: Yirga Alem Hospital, Yirga Alem, Ethiopia.
authors.forename: A
authors.initials: A
authors.lastname: Belihu
authors.forename: B
authors.initials: B
authors.lastname: Lindtjorn
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D004352:Drug Resistance, Microbial; D005002:Ethiopia; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests; D013997:Time Factors; D014552:Urinary Tract Infections / Q000382:microbiology; D014946:Wound Infection / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents