[Desquamative interstitial pneumonia--case report and review of literature].
A 50-year-old man was admitted to our hospital because diffuse reticulonodular shadows in the bilateral lung fields had deteriorated on chest radiographs during a regular checkup. The bronchoalveolar lavage (BAL) fluid revealed an increase in the total number of cells, including slightly elevated levels of eosinophils and neutrophils. The thoracoscopic lung biopsy specimens showed findings compatible with desquamative interstitial pneumonia (DIP). Corticosteroid therapy was done, and improvement of chest CT findings and pulmonary function were seen. We reviewed the clinical features in seventeen patients with biopsy-proven DIP reported in Japan. All patients have good prognoses and a high frequency of steroid responsiveness. Moreover, many patients were positive for antinuclear antibodies in serological tests, and there was a tendency toward increasing eosinophils in BAL fluids.
Ishii
Hiroshi
H
Second Department of Internal Medicine, Nagasaki University School of Medicine.
Mukae
Hiroshi
H
Matsunaga
Yuko
Y
Kakugawa
Tomoyuki
T
Nagata
Towako
T
Kaida
Hideyuki
H
Sakamoto
Noriho
N
Tsurutani
Hiroko
H
Kadota
Jun-ichi
J
Kohno
Shigeru
S
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D011379:Prognosis
D000893:Anti-Inflammatory Agents; D011239:Prednisolone