title: [Universal newborn hearing screening program in Würzburg. Experience with more than 4000 newborns and the influence of non-pathological factors on the test results].
abstract: BACKGROUND
  The BERAphon(R) method employing a special headphone and the time-course step-stimulus algorithm offers a quick and reliable tool for universal hearing screening in newborns. An ABR-based universal newborn hearing screening program has been established in Würzburg since August, 1997. Until August 2001, 4115 newborns have undergone primary and/or control-screening with the BERAphon(R). The validity of this method was further examined by testing the effects of non-pathological factors such as gender, age, Apgar score, pH value of the umbilical cord, head circumference and duration of pregnancy on the ABR wave V latency in 415 infants.
  
  
  RESULTS
  Out of 3930 infants who were primary screened, 27 infants were diagnosed to have hearing loss. Furthermore, hearing loss was detected in 35 out of 185 infants referred for control screening. Non-pathological factors showed a minor effect on the test results. Apgar score, gender or chronological age did not have any significant effects on the latency of wave V. Duration of pregnancy, pH value of the umbilical cord or head circumference showed a significant but weak correlation with wave V latency.
  
  
  CONCLUSIONS
  Only non-pathological factors related to maturation had a minor effect on ABR measurements using the time-course-step-stimulus algorithm. The BERAphon(R) method has proven to be a reliable, robust method giving information related to the hearing threshold and accordingly can be used reliably for hearing screening in newborn infants.
authors.affiliation: Bayerische Julius-Maximilians-Universität, Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Würzburg, Germany. hnok038@mail.uni-wuerzburg.de
authors.forename: W E
authors.initials: WE
authors.lastname: Shehata-Dieler
authors.forename: R
authors.initials: R
authors.lastname: Dieler
authors.forename: G
authors.initials: G
authors.lastname: Wenzel
authors.forename: R
authors.initials: R
authors.lastname: Keim
authors.forename: D
authors.initials: D
authors.lastname: Singer
authors.forename: Ch
authors.initials: Ch
authors.lastname: von Deuster
mesh_terms: D001300:Audiometry, Evoked Response; D001933:Brain Stem / Q000503:physiopathology; D003638:Deafness / Q000151:congenital* / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening; D011237:Predictive Value of Tests; D011247:Pregnancy; D012307:Risk Factors