title: [Acetylcholine receptor antibodies in patients with myasthenia].
abstract: Acethylcholine receptor (AChR) antibodies in patients with myasthenia were studied for the first time in Russia with radioimmuno-assay application. Seronegative result (antibody titer lower than 0.2 nmol/l) was obtained for 33% of the patients and seropositive one (antibody titer higher than 0.2 nmol/l)--for 67%. AChR antibodies level varied from 1.9 to 115.0 nmol/l. The AChR antibodies were found more frequently and in higher titers in women than in men. Correlation analysis revealed strong correlation between AChR antibodies level and severity of myasthenia.
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Neretin
authors.forename: S V
authors.initials: SV
authors.lastname: Kotov
authors.forename: B M
authors.initials: BM
authors.lastname: Gekht
authors.forename: B V
authors.initials: BV
authors.lastname: Agafonov
authors.forename: G
authors.initials: G
authors.lastname: Lokhmiuller
authors.forename: O P
authors.initials: OP
authors.lastname: Sidorova
authors.forename: E K
authors.initials: EK
authors.lastname: Sepp
authors.forename: N I
authors.initials: NI
authors.lastname: Shcherbakova
authors.forename: S G
authors.initials: SG
authors.lastname: Kalinenkova
mesh_terms: D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000453:epidemiology / Q000276:immunology* / Q000601:surgery; D011182:Postoperative Care; D011300:Preoperative Care; D011950:Receptors, Cholinergic / Q000276:immunology*; D012720:Severity of Illness Index; D013934:Thymectomy
chemical_list: D000906:Antibodies; D011950:Receptors, Cholinergic