title: Unexpected response of a pulmonary blastoma on radiotherapy: a case report and review of the literature.
abstract: Pulmonary blastoma (PB) is a rare malignant tumor of the lung. Treatment is primarily surgical, although, combination chemotherapy has been reported to result in objective responses in inoperable tumors or after incomplete resections. To our knowledge, this is the first report of a very radiosensitive PB, which showed major tumor reduction after several fractions of radiotherapy without further tumor regression after additional chemotherapy with cisplatin and etoposide. The literature on the treatment of PB is reviewed.
authors.affiliation: Department of Pulmonology, Respiratory Oncology Unit, University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium. veerle.surmont@uz.kuleuven.ac.be
authors.forename: Veerle F
authors.initials: VF
authors.lastname: Surmont
authors.forename: Rob J
authors.initials: RJ
authors.lastname: van Klaveren
authors.forename: Peter J C M
authors.initials: PJ
authors.lastname: Nowak
authors.forename: Pieter E
authors.initials: PE
authors.lastname: Zondervan
authors.forename: Henk C
authors.initials: HC
authors.lastname: Hoogsteden
authors.forename: Jan P
authors.initials: JP
authors.lastname: van Meerbeeck
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D004847:Epithelial Cells / Q000473:pathology; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D018202:Pulmonary Blastoma / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D017154:Stromal Cells / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D005047:Etoposide; D002945:Cisplatin