A convenient preparation of 3-substituted furans: synthesis of perillene and dendrolasin.
A variety of 3-substituted furans, including the natural products perillene and dendrolasin, are obtained in good yield via reductive annulation of 1,1,1-trichloroethyl propargyl ethers using catalytic Cr(II) regenerated by Mn/TMSCl. [reaction: see text]
Barma
D K
DK
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9038, USA.
Kundu
Abhijit
A
Baati
Rachid
R
Mioskowski
Charles
C
Falck
J R
JR
D000080462:Acyclic Monoterpenes; D000478:Alkylation; D002712:Chlorides; D017608:Chromium Compounds; D005663:Furans / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D039821:Monoterpenes
D000080462:Acyclic Monoterpenes; D002712:Chlorides; D017608:Chromium Compounds; D005663:Furans; D007202:Indicators and Reagents; D039821:Monoterpenes; C454810:dendrolasin; C090823:perillene; C017133:chromous chloride