Management of cutaneous leishmaniasis.
There is an urgent need for a safe, effective, easily administered and cheap treatment for cutaneous leishmaniasis. Unfortunately it remains elusive. There have been a number of contributions during the last year, but none will change present day management. The diagnosis of cutaneous leishmaniasis is established on the basis of a typical lesion, a history of exposure and demonstration of the parasite. Molecular methods, usually based on kinetoplast DNA, are being developed and used increasingly to diagnose and type the infecting organism. Pentavalent antimonials remain the mainstay of treatment.
Hepburn
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Department of Dermatology, County Hospital, Lincoln, UK. Neill.Hepburn@ULH.NHS.UK
D000818:Animals; D000965:Antimony / Q000627:therapeutic use; D000967:Antimony Sodium Gluconate / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D006801:Humans; D007891:Leishmania / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D008297:Male; D051379:Mice
D000981:Antiprotozoal Agents; D000965:Antimony; D000967:Antimony Sodium Gluconate