When can cytomegalovirus prophylaxis and maintenance therapy be stopped in HIV disease?
Highly active antiretroviral therapy (HAART) can restore immune responses to a variety of pathogens, including cytomegalovirus. Following successful HAART, prophylaxis and maintenance therapy for cytomegalovirus can safely be stopped in selected patients. However, the risk of cytomegalovirus disease progression recurs if HAART fails, and so these patients require careful monitoring.
Deayton
Jane R.
JR
Department of Virology, Royal Free and University College Medical School, London, UK.
Griffiths
Paul D.
PD