Level of serum cytokines in biliary gastritis and erosive gastritis with Helicobacter pylori coinfection.
The aim of this study was evaluation of serum cytokines level in patients with biliary and erosive gastritis. 50 patients were admitted to this study: 20 with biliary, 20 with erosive gastritis and 10 as the control group. In all patients serum levels of Il-8, Il-6R, Il-2R were evaluated. In each group half patients were infected by Helicobacter pylori, and the second half were uninfected. Mean level of Il-8 in patients with biliary gastritis was higher than in those in the control group, and was more increased in Helicobacter pylori infected patients than in uninfected ones. In erosive gastritis accompanied by Helicobacter pylori infection mean level of Il-8 was higher than in uninfected patients for which the level was normal. Serum Il-6R levels in biliary gastritis with infection by Helicobacter pylori were higher than in biliary gastritis without infection. These values were statistically significant vs. the control group. In erosive gastritis accompanied by Helicobacter pylori mean level of Il-6R was higher than in the control group, but was normal in patients without Helicobacter pylori. We noticed no influence of Helicobacter pylori infection on Il-2R levels in patients with biliary gastritis and erosive gastritis. These levels were normal in all groups of patients. In conclusion, in biliary gastritis we found the levels of Il-8, Il-6R higher than in erosive gastritis. Particularly significantly high levels of Il-8, Il-6R were observed in gastritis accompanied by Helicobacter pylori infection.
Cichoz-Lach
H
H
Department of Gastroenterology, Medical University of Lublin.
Słomka
M
M
Celiński
K
K
Baczek
A
A
D000328:Adult; D000368:Aged; D016207:Cytokines / Q000097:blood*; D005260:Female; D005756:Gastritis / Q000097:blood*; D016481:Helicobacter Infections / Q000097:blood*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged
D016207:Cytokines