title: Nosocomial pneumonia: epidemiology, pathogenesis, diagnosis, treatment and prevention.
abstract: Nosocomial pneumonia is the second most common nosocomial infection and the leading cause of death from hospital-acquired infection. Supine body position in mechanically ventilated patients, and cardiopulmonary resuscitation and continuous sedation are significant risk factors for developing nosocomial pneumonia. During the past 2 years some new therapeutic approaches for nosocomial pneumonia and modifications to established therapies have been described, such as optimal pharmacodynamic evaluations, monotherapy versus combination therapy, computer-assisted management programmes and antibiotic rotations.
authors.affiliation: aDepartment of Chest and Infectious Diseases and bInstitute of Medical Microbiology, Hospital Heckeshorn, affiliated to Freie Universität Berlin, Berlin, Germany.
authors.forename: Hartmut
authors.initials: H
authors.lastname: Lode
authors.forename: Manfred
authors.initials: M
authors.lastname: Raffenberg
authors.forename: Reiner
authors.initials: R
authors.lastname: Erbes
authors.forename: Hilte
authors.initials: H
authors.lastname: Geerdes-Fenge
authors.forename: Harald
authors.initials: H
authors.lastname: Mauch