title: Bacteriophage SP6 is closely related to phages K1-5, K5, and K1E but encodes a tail protein very similar to that of the distantly related P22.
abstract: The lytic salmonella phage SP6 encodes a tail protein with a high degree of sequence similarity to the tail protein of the biologically unrelated lysogenic salmonella phage P22. The SP6 tail gene is flanked by an upstream region that contains a promoter and a downstream region that contains a putative Rho-independent transcription terminator, giving it a cassette or modular structure almost identical to the structure of the tail genes of coliphages K1E, K5, and K1-5. It now appears that SP6, K1-5, K5, and K1E are very closely related but have different tail fiber proteins, giving them different host specificities.
authors.affiliation: Laboratory of Biochemical Genetics, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.
authors.forename: Dean
authors.initials: D
authors.lastname: Scholl
authors.forename: Sankar
authors.initials: S
authors.lastname: Adhya
authors.forename: Carl R
authors.initials: CR
authors.lastname: Merril
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003090:Coliphages / Q000235:genetics*; D004265:DNA Helicases / Q000235:genetics; D012321:DNA-Directed RNA Polymerases / Q000235:genetics; D008969:Molecular Sequence Data; D012483:Salmonella Phages / Q000235:genetics*; D017376:Viral Tail Proteins / Q000737:chemistry / Q000235:genetics*; D014771:Virion / Q000235:genetics
chemical_list: D017376:Viral Tail Proteins; D012321:DNA-Directed RNA Polymerases; D004265:DNA Helicases