Prediction of human pharmacokinetics based on preclinical in vitro and in vivo data.
Lavé
T
T
F.-Hoffmann-La Roche Inc, Drug Discovery Support, PRBN 68/329, Grenzacherstrasse 124, 4070 Basel, Switzerland. thierry.lave@roche.com
Luttringer
O
O
Zuegge
J
J
Schneider
G
G
Coassolo
P
P
Theil
F P
FP
D015195:Drug Design; D004345:Drug Industry / Q000379:methods; D006801:Humans; D015233:Models, Statistical; D016571:Neural Networks, Computer; D010599:Pharmacokinetics; D013997:Time Factors