title: Thalamic stroke secondary to straight sinus thrombosis in a nephrotic child.
abstract: A 7-year-old Chinese boy with steroid-resistant nephrotic syndrome developed thalamic stroke secondary to straight sinus thrombosis. He was hospitalized due to status epilepticus and coma. The child recovered after treatment by low-molecular-weight heparin (LMWH) and warfarin. This case highlights the importance of magnetic resonance imaging with venography in the early diagnosis of cerebral sinus thrombosis (CST) in nephrotic children and the effectiveness of anticoagulation therapy in improving the neurological outcome.
authors.affiliation: Department of Pediatrics, Division of Pediatric Nephrology, Chang Gung Memorial Hospital at Kaohsiung, 123 Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan, Republic of China.
authors.forename: Chih-Chong
authors.initials: CC
authors.lastname: Lin
authors.forename: Chun-Chung
authors.initials: CC
authors.lastname: Lui
authors.forename: You-Lin
authors.initials: YL
authors.lastname: Tain
mesh_terms: D002648:Child; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications*; D012851:Sinus Thrombosis, Intracranial / Q000150:complications* / Q000175:diagnosis; D020521:Stroke / Q000188:drug therapy / Q000209:etiology*; D013786:Thalamic Diseases / Q000188:drug therapy / Q000209:etiology*
chemical_list: D006495:Heparin, Low-Molecular-Weight