title: Liver involvement in alpha1-antitrypsin-deficient phenotypes PiSZ and PiMZ.
abstract: The long-term outcome of 3 PiSZ and 57 PiMZ children affected by alpha1-antitrypsin deficiency-associated liver involvement during infancy was assessed. At 5 and 10 y of age all PiSZ and PiMZ children exhibited normal levels of liver enzymes. All families, except one, were deterred from smoking following counselling.
  
  
  CONCLUSIONS
  Transient liver involvement observed during early infancy is likely to be a benign self-limiting process.
authors.affiliation: Department of Paediatrics, Regional Hospital, Bozen, Italy. pediat@asbz.provincia.bz.it
authors.forename: K
authors.initials: K
authors.lastname: Pittschieler
mesh_terms: D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008099:Liver / Q000503:physiopathology*; D015997:Neonatal Screening; D010641:Phenotype; D019896:alpha 1-Antitrypsin Deficiency / Q000503:physiopathology*