title: Preoperative chemoembolization for unresectable hepatoblastoma.
abstract: Complete surgical resection offers the only chance for cure in patients with hepatoblastoma (HB). Patients with unresectable lesions are given preoperative chemotherapy in an attempt to create a resectable lesion. We present a case of an 11-month-old with an unresectable stage III HB unresponsive to systemic chemotherapy. Transfemoral hepatic-artery chemoembolization resulted in a surgically resectable tumor. The patient underwent a right trisegmentectomy with complete resection of the tumor and remains tumor-free 24 months postoperatively. Salvage chemoembolization can be an effective preoperative modality to convert an unresectable tumor into a resectable one.
authors.affiliation: Division of Pediatric Surgery, Baystate Medical Center Children's Hospital, Tufts University School of Medicine, Springfield, MA, USA.
authors.forename: David B
authors.initials: DB
authors.lastname: Tashjian
authors.forename: Kevin P
authors.initials: KP
authors.lastname: Moriarty
authors.forename: Richard A
authors.initials: RA
authors.lastname: Courtney
authors.forename: Mark S
authors.initials: MS
authors.lastname: Bean
authors.forename: David A
authors.initials: DA
authors.lastname: Steele
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D016461:Chemoembolization, Therapeutic; D002945:Cisplatin / Q000008:administration & dosage*; D004317:Doxorubicin / Q000008:administration & dosage*; D018197:Hepatoblastoma / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000601:surgery / Q000628:therapy*; D008297:Male; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed
chemical_list: D004317:Doxorubicin; D002945:Cisplatin