title: Non-occlusive mesenteric ischemia: etiology, diagnosis, and interventional therapy.
abstract: Non-occlusive mesenteric ischemia (NOMI) compromises all forms of mesenteric ischemia with patent mesenteric arteries. It generally affects patients over 50 years of age suffering from myocardial infarction, congestive heart failure, aortic insufficiency, renal or hepatic disease and patients following cardiac surgery. Non-occlusive disease accounts for 20-30% of all cases of acute mesenteric ischemia with a mortality rate of the order of 50%. Acute abdominal pain may be the only early presenting symptom of mesenteric ischemia. Non-invasive imaging modalities, such as CT, MRI, and ultrasound, are able to evaluate the aorta and the origins of splanchnic arteries. Despite the technical evolution of those methods, selective angiography of mesenteric arteries is still the gold standard in diagnosing peripheral splanchnic vessel disease. In early non-occlusive mesenteric ischemia, as opposed to occlusive disease, there is no surgical therapy. It is known that mesenteric vasospasm persists even after correction of the precipitating event. Vasospasm frequently responds to direct intra-arterial vasodilator therapy, which is the only treatment that has been shown to be effective.
authors.affiliation: Department of Radiology, Städtisches Klinikum Karlsruhe, Academic Teaching Hospital of the University of Freiburg, Moltkestrasse 90, 76133 Karlsruhe, Germany. markus.trompeter@t-online.de
authors.forename: Markus
authors.initials: M
authors.lastname: Trompeter
authors.forename: Thurid
authors.initials: T
authors.lastname: Brazda
authors.forename: Christopher T
authors.initials: CT
authors.lastname: Remy
authors.forename: Thomas
authors.initials: T
authors.lastname: Vestring
authors.forename: Peter
authors.initials: P
authors.lastname: Reimer
mesh_terms: D000792:Angiography; D003937:Diagnosis, Differential; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D017078:Laser-Doppler Flowmetry; D008279:Magnetic Resonance Imaging; D008638:Mesenteric Arteries / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D014665:Vasodilator Agents