CT and MRI appearances of methotrexate leucoencephalopathy.
Methotrexate is a well recognised cause of diffuse symmetrical leucoencephalopathy. The widespread use of the drug in chemotherapeutic regimes necessitates awareness of this complication. A case report and a brief literature review is presented.
Wilks
Michael J
MJ
Radiology Department, The Queen Elizabeth Hospital, Woodville, South Australia, Australia. kat@esc.net.au
Tie
Mark L H
ML
Pozza
Christopher H
CH
D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008727:Methotrexate / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate