Vesicle tethers promoting fusion machinery assembly.
In a recent issue of the Journal of Cell Biology, Shorter et al. demonstrate that p115, a vesicle tethering protein, binds specific SNAREs, key components of the membrane fusion machinery, and uncover that this interaction promotes the assembly of the fusion machinery.
Söllner
Thomas H
TH
Cellular Biochemistry and Biophysics Program, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10021, USA.
D002352:Carrier Proteins / Q000378:metabolism*; D022162:Cytoplasmic Vesicles / Q000378:metabolism*; D000077614:Golgi Matrix Proteins; D008561:Membrane Fusion / Q000502:physiology*; D008565:Membrane Proteins / Q000378:metabolism*; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins
D002352:Carrier Proteins; D000077614:Golgi Matrix Proteins; D008565:Membrane Proteins; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins; C091580:vesicular transport factor p115