[Effect of Azospirillum brasilense lectin on the kinetics of lymph nodes cell populations and cytokine status in experimental animals].
The complex study of the influence of A. brasilense Sp 7 lectin with carbohydrate specificity to L-fucose and D-galactose on the dynamics of cell populations in different structural functional zones of the white mice mesentery, as well as on the capacity of immunocompetent cells of mesenterial lymph nodes for synthesizing cytokines (interleukin-1, interleukin-6 and tumor necrosis factor), was carried out. A single oral administration of bacterial lectin in a dose of 4.5 micrograms produced a pronounced immunostimulating effect.
Nikitina
V E
VE
Institute of Biochemistry and Physiology of Plants and Microorganisms, State Medical University, Chernyshevsky State University, Saratov.
Bugaeva
I O
IO
Ponomareva
E G
EG
Tikhomirova
E I
EI
Bogomolova
N V
NV
D000818:Animals; D015806:Azospirillum brasilense; D002453:Cell Cycle / Q000187:drug effects; D016207:Cytokines / Q000187:drug effects* / Q000378:metabolism*; D037102:Lectins / Q000302:isolation & purification / Q000494:pharmacology*; D008198:Lymph Nodes / Q000166:cytology* / Q000187:drug effects*; D018655:Lymphocyte Count; D008297:Male; D051379:Mice
D016207:Cytokines; D037102:Lectins