title: Cloning and characterization of a novel isoform of calpastatin in human adult testis.
abstract: OBJECTIVE
  To clone a new gene related to human spermatogenesis.
  
  
  METHODS
  cDNA probes of embryo and adult testis were used to hybridize the cDNA microarray of adult testis, and the clones of differential hybridization were sequenced and analyzed.
  
  
  RESULTS
  A novel isoform of calpastatin exclusively and highly expressed in human adult testis was found.
  
  
  CONCLUSIONS
  A novel isoform of calpastatin expresses in human testis and it is related to spermatogenesis.
authors.affiliation: Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029  China. shajh@njmu.edu.cn
authors.forename: Hu
authors.initials: H
authors.lastname: Zhu
authors.forename: Zuo-Min
authors.initials: ZM
authors.lastname: Zhou
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Li
authors.forename: Hui
authors.initials: H
authors.lastname: Zhu
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Cheng
authors.forename: Yu-Xi
authors.initials: YX
authors.lastname: Shan
authors.forename: Lan-Lan
authors.initials: LL
authors.lastname: Yin
authors.forename: Jia-Hao
authors.initials: JH
authors.lastname: Sha
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D001483:Base Sequence; D002135:Calcium-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D002154:Calpain / Q000037:antagonists & inhibitors*; D003001:Cloning, Molecular; D005333:Fetus; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D020033:Protein Isoforms / Q000235:genetics / Q000378:metabolism; D013091:Spermatogenesis / Q000235:genetics; D013737:Testis / Q000378:metabolism*
chemical_list: D002135:Calcium-Binding Proteins; D020033:Protein Isoforms; C033668:calpastatin; D002154:Calpain