CT and MRI findings of cyclosporine-related encephalopathy and hypertensive encephalopathy.
We present the MRI and CT findings of one child with cyclosporine-related encephalopathy, and one child with hypertensive encephalopathy following cyclosporine-related encephalopathy. The imaging findings were shown well on T2-weighted and fluid-attenuated inversion recovery (FLAIR) MR images. Cyclosporine-related encephalopathy was distributed predominantly in the posterior white matter. Hypertensive encephalopathy showed similar changes of CT attenuation, but with wider distribution. These two disorders seem to have the same pathogenesis.
Yamamoto
Akira
A
1-2 Higashitakada-cho, Mibu, Nakagyo-ku, Kyoto-shi, Kyoto-fu, Japan. MXA00205@nifty.ne.jp
Hayakawa
Katsumi
K
Houjyou
Makoto
M
D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging*; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis*; D002648:Child; D002669:Child Welfare; D016572:Cyclosporine / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D020343:Hypertensive Encephalopathy / Q000139:chemically induced* / Q000175:diagnosis*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D011183:Postoperative Complications / Q000209:etiology; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure
D007166:Immunosuppressive Agents; D016572:Cyclosporine