title: MR-guided percutaneous core biopsy of small breast lesions: first experience with a vertically open 0.5T scanner.
abstract: OBJECTIVE
  The growing use of highly sensitive but only moderate specific breast MRI requires the development of both minimal-invasive as well as precise biopsy systems. The aim of the study was to prove the accuracy and feasibility of a biopsy procedure carried out in prone position in a vertically opened MR imager.
  
  
  METHODS
  The biopsies were carried out in 21 women with lesions visible on MRI alone using an open breast coil with an integrated biopsy device. A 14 G coaxial needle was placed under near real-time MRI-guidance. After the tip of this needle was verified in contact with the lesion, we used a non MR-compatible, but MR-safe biopsy gun with a 16 G canula to take four to eight cores.
  
  
  RESULTS
  We found eight malignant and 12 benign lesions. In one patient the procedure was not successful. In case of malignancy, the operation confirmed the diagnosis in all cases. The 12/21 patients with benign lesions have been followed without evidence of lesions growth over eight to 28 months.
  
  
  CONCLUSIONS
  The described procedure allows MRI-guided minimal invasive core biopsy of small breast lesions (five to 17 mm) with a high degree of accuracy.
authors.affiliation: Department of Diagnostic Radiology, University of Leipzig, Leipzig, Germany. schneidj@medizin.uni-leipzig.de
authors.forename: Jens P
authors.initials: JP
authors.lastname: Schneider
authors.forename: Thomas
authors.initials: T
authors.lastname: Schulz
authors.forename: Lars C
authors.initials: LC
authors.lastname: Horn
authors.forename: Steffen
authors.initials: S
authors.lastname: Leinung
authors.forename: Frank
authors.initials: F
authors.lastname: Schmidt
authors.forename: Thomas
authors.initials: T
authors.lastname: Kahn
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods*; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged