title: Study of the patency of small arterial branches after stent placement with an experimental in vivo model.
abstract: OBJECTIVE
  The patency of intracranial perforating arteries after stent placement is unknown despite the general clinical use of intracranial arterial stenting.
  
  
  METHODS
  We deployed stainless steel stents in the abdominal aorta across the lumbar artery in eight normal rabbits in which the diameters of the abdominal arterial vessels were similar to those of human intracranial arteries. We evaluated the patency via angiographic and scanning electron microscopic methods 3 months after stent placement. Histopathologic evaluation was also performed for one rabbit.
  
  
  RESULTS
  The lumbar arteries were patent, even when stent struts crossed the ostium, except in one rabbit in which intimal dissection occurred intraoperatively. The scanning electron microscopy showed that the regenerative endothelium had grown onto the strut at the ostium of the lumbar artery.
  
  
  CONCLUSIONS
  We confirmed the patency of the lumbar arteries in this study by using normal rabbits. Thus, intracranial stenting may not pose a risk of occluding perforating arteries of the same diameter of the lumbar artery, even if stent struts cover the ostium.
authors.affiliation: Department of Neurological Surgery, Kansai College of Oriental Medicine, Osaka, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Masuo
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Terada
authors.forename: Gary
authors.initials: G
authors.lastname: Walker
authors.forename: Mitsuharu
authors.initials: M
authors.lastname: Tsuura
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tohya
authors.forename: Michio
authors.initials: M
authors.lastname: Kimura
authors.forename: Kunio
authors.initials: K
authors.lastname: Nakai
authors.forename: Toru
authors.initials: T
authors.lastname: Itakura
mesh_terms: D000009:Abdominal Muscles / Q000098:blood supply; D000818:Animals; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging; D001158:Arteries / Q000000981:diagnostic imaging; D002536:Cerebral Arteries; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D011859:Radiography; D013193:Stainless Steel; D015607:Stents; D014463:Ultrasonography; D014654:Vascular Patency
chemical_list: D013193:Stainless Steel