title: Prospective randomized comparison of laparoscopic-assisted vaginal hysterectomy (LAVH) with abdominal hysterectomy (AH) for the treatment of the uterus weighing >200 g.
abstract: BACKGROUND
  Laparoscopic-assisted vaginal hysterectomy (LAVH) can be used for the vaginal removal of large uteri (200 g), which are conventionally treated with an abdominal approach (AH).
  
  
  METHODS
  Forty-eight women with a sonographically estimated uterine weight of >200 g were prospectively randomized to undergo either LAVH (n = 28) or AH (n = 20).
  
  
  RESULTS
  The median uterus weight was 334 g for LAVH vs 428 g for AH (not significant). The median operative time (133 vs 132 min) and duration of recuperation (42 vs 42 days) were similar. LAVH was associated with significantly less intraoperative blood loss (median, 200 vs 600 ml; p < 0.05), a lower pain index at postoperative day 4 (median [who scale], 0 VS 5; P < 0.05), a lower decrease in hemoglobin (median,-0.6 VS -1.55 MG/DL; P < 0.05), and a lower decrease in hematocrit (median, -0.03% VS -0.07%; P < 0.05). There were no significant differences in the frequency of postoperative complications (14.3% for LAVH VS 30% for AH). Although all LAVH patients who answered the questionnaire said they would undergo the same procedure again, only 45% of the AH group were satisfied (P < 0.05).
  
  
  CONCLUSIONS
  For the treatment of uteri >200 g, LAVH has several advantages over AH: lower postoperative morbidity, quicker short-term recuperation, and better patient acceptance.
authors.affiliation: Department of Gynecology, Friedrich Schiller University, Bachstrasse 18, 07740 Jena, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Schütz
authors.forename: M
authors.initials: M
authors.lastname: Possover
authors.forename: A
authors.initials: A
authors.lastname: Merker
authors.forename: W
authors.initials: W
authors.lastname: Michels
authors.forename: A
authors.initials: A
authors.lastname: Schneider
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical / Q000503:physiopathology; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects / Q000379:methods; D007045:Hysterectomy, Vaginal / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D008875:Middle Aged; D009929:Organ Size / Q000502:physiology; D011446:Prospective Studies; D011897:Random Allocation; D016896:Treatment Outcome; D014463:Ultrasonography; D014599:Uterus / Q000000981:diagnostic imaging