title: Regioselective synthesis of 3-alkylindoles mediated by zinc triflate.
abstract: Zinc triflate was found to be an effective reagent for the C3-alkylation of indoles by alkyl halides in the presence of Hünig's base and tetrabutylammonium iodide. This new method for indole alkylation proceeds by a S(N)1-like pathway, and is general for allylic, benzylic, and tertiary halides.
authors.affiliation: Department of Chemistry, University of Southampton, Southampton SO17 1BJ, United Kingdom.
authors.forename: Xiuwen
authors.initials: X
authors.lastname: Zhu
authors.forename: A
authors.initials: A
authors.lastname: Ganesan