title: Aryl-aryl coupling reaction using a novel and highly active palladium reagent prepared from Pd(OAc)2, 1,3-bis[diphenylphosphino]propane (DPPP), and Bu3P.
abstract: A palladium-assisted coupling reaction of aryl triflate with arene was investigated, and a novel Pd reagent prepared from equimolar Pd(OAc)2, 1,3-Bis[diphenylphosphino]propane (DPPP), and Bu3P was developed. This method is useful for intramolecular biaryl coupling reactions, not only between aryl triflate and arene (triflate-amide), but also between aryl halide and arene (halo-amide).
authors.affiliation: Faculty of Pharmaceutical Sciences, Okayama University, Japan. harayama@pharm.okayama-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Harayama
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Akiyama
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Nakano
authors.forename: Hiromi
authors.initials: H
authors.lastname: Nishioka
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Abe
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Takeuchi
mesh_terms: D003500:Cyclization; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D011407:Propane / Q000031:analogs & derivatives / Q000737:chemistry*
chemical_list: D006841:Hydrocarbons, Aromatic; D007202:Indicators and Reagents; D009942:Organometallic Compounds; D010720:Phosphines; C043255:tri-n-butylphosphine; C467590:1,3-bis(diphenylphosphino)propane; D010165:Palladium; D011407:Propane