In vitro tests to evaluate potential biological activity in natural substances.
The biological activity of polysaccharides from the mycelia of 40 Basidiomycetes was studied using an uncommon toxicity test technique, the planaria bioassay, and the better known potato disk bioassay. The results showed the utility of this duo of 'in vitro' tests as a preliminary screening of the toxicity of substances that are present in aqueous fungal extracts.
Nano
G M
GM
Dipartimento di Scienza e Tecnologia del Farmaco, Universita' di Torino, Via Pietro Giuria, 9 10125, Torino, Italy. gianmario.nano@unito.it
Binello
A
A
Bianco
M A
MA
Ugazio
G
G
Burdino
S
S
D016960:Agrobacterium tumefaciens / Q000187:drug effects*; D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001487:Basidiomycota; D008826:Microbial Sensitivity Tests / Q000592:standards; D008517:Phytotherapy; D010932:Planarians / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology; D010941:Plant Tumors; D011134:Polysaccharides / Q000494:pharmacology*; D012680:Sensitivity and Specificity; D011198:Solanum tuberosum
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010936:Plant Extracts; D011134:Polysaccharides