[Immunomodulating effect of electromagnetic waves on production of tumor necrosis factor in mice with various rates of neoplasm growth].
The effects of low-density centimeter waves (8.15-18 GHz, 1 microW/cm2, 1 h daily for 14 days; MW) on tumor necrosis factor production in macrophages of mice with different growth rate of a cancer solid model produced after hypodermic injection of Ehrlich carcinoma ascites cells into hind legs were studied. After irradiation, an increase in the concentration of tumor necrosis factor in immunocompetent cells of healthy and, specially, of tumor-bearing animals was observed; and the effect of stimulation was higher upon exposure of mice carrying rapidly growing tumors. We suggest that the significant immunomodulating effect of low-density microwaves can be utilized for tumor growth suppression.
Glushkova
O V
OV
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russia.
Novoselova
E G
EG
Sinotova
O A
OA
Vrublevskaia
V V
VV
Fesenko
E E
EE
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D004574:Electromagnetic Fields; D017737:Macrophages, Peritoneal / Q000378:metabolism; D008297:Male; D051379:Mice; D013601:T-Lymphocytes / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis*
D014409:Tumor Necrosis Factor-alpha