[CD8-positive, CD30-negative cutaneous T-cell lymphoma simulating pyoderma gangrenosum].
Ulcerated primary cutaneous lymphomas are not rare, but the clinical manifestation as a pyoderma gangrenosum look-alike is extraordinary. CD8-positive lymphomas are rare, unclassifiable tumours with variable prognosis. We report on a 49-year-old patient with a large ulcerated primary cutaneous lymphoma on the left chest wall presenting as pyoderma gangrenosum. With immunohistochemical staining, most lymphocytes were shown to be CD8-positive. The CD30 antigen was not expressed. After radiotherapy with complete skin irradiation, the lymphoma regressed completely. The patient has been free of relapse for 28 months so far.
Dueck
D
D
Krankenhaus Neukölln, Abteilung für Dermatologie und Venerologie, Rudower Strasse 48, 12351 Berlin.
Hermes
B
B
Audring
H
H
Kohl
P K
PK
D016827:CD8 Antigens / Q000032:analysis*; D003937:Diagnosis, Differential; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis*; D008214:Lymphocytes / Q000473:pathology; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D017511:Pyoderma Gangrenosum / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy
D016827:CD8 Antigens; D017730:Ki-1 Antigen