[Desmoplastic small round cell tumor: report of 2 cases].
OBJECTIVE
To recognize the characteristics of desmoplastic small round cell tumor (DSRCT) and improve the standard of diagnosis.


METHODS
We retrospectively reviewed the clinical data on the treatment of 2 patients with DSRCT in terms of their conditions, tissue sources, pathologic characteristics, immunohistochemical methods, clinical manifestation, diagnosis, treatment and prognosis.


RESULTS
Clinical manifestations were complicated. The 2 patients were mis diagnosed before operation. Their tumors consisted of irregular nests of small and round cells, with nuclear hyperchromatism and scant cytoplasm embedded in a plenty of fibrous connective tissues. The edge of the nest was clear, with different sizes and shapes. Immunohistochemically, the 2 patients were positive for CK or EMA, NSE, des and vim of the epithelium, nerve, muscle and interstitial. They died 9 months after operation.


CONCLUSIONS
The tumor may occur in the abdomen, pelvic cavity and other sites, with different clinical manifestations. Routine examination should be replaced by immunohistochemical test for correct diagnosis of the tumor. Prognosis of most patients is not good.
Hu
Zili
Z
Department of Urology, Second Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing 400010, China.
Leng
Zhi
Z
Zhang
Weili
W
Qiao
Tianyu
T
Yang
Guangyong
G
Xu
Guangyong
G
Liu
Chuan
C
D000293:Adolescent; D018288:Carcinoma, Small Cell / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009372:Neoplasms, Connective Tissue / Q000175:diagnosis*; D012189:Retrospective Studies