[Breast feeding and treatment with antidepressive agents. A literature review].
Depression after delivery occurs frequently and, apart from being very painful, it may cause disturbance in the child's development. A number of these depressions are so severe that medical antidepressant treatment is indicated. This raises the question whether this kind of treatment should call for interruption of breast-feeding. The problem is, however, that breast-feeding is of major importance to the child, as well as to the mother. A review of present knowledge about the excretion of antidepressants in breast milk and the reports on the possible effects on the child would be useful, in order to create a qualified basis for decision-making, together with the patient, on whether or not to interrupt the breast-feeding. Furthermore, examination of the references would result in concrete guidelines for the most appropriate way of dealing with the treatment, if it is decided to continue the breast-feeding.
Videbech
Poul
P
Institut for psykiatrisk grundforskning, afdeling for biologisk psykiatri, Psykiatrisk Hospital i Arhus, DK-8240 Risskov.
D000928:Antidepressive Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D001942:Breast Feeding / Q000009:adverse effects; D002657:Child Development / Q000187:drug effects*; D019052:Depression, Postpartum / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008895:Milk, Human / Q000737:chemistry*; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics
D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D017367:Selective Serotonin Reuptake Inhibitors