Comparison between the role of discontinuities in cardiac conduction and in a one-dimensional hardware model.
In real electrophysiological experiments, irregularities in the extracellular excitation spread are believed to depend on cardiac tissue microstructure. An electronic hardware model was developed to analyze this dependence by placing some inhomogeneities (slow propagation areas) in the medium. The position of such inhomogeneities is correlated with abnormal delays and irregularities measured in signal propagation.
deCastro
M
M
Grupo de Fisica No Lineal, Facultad de Fisica, Universidad Santiago de Compostela, 15706 Santiago de Compostela, Spain. uscfmmcr@cesga.es
Hofer
E
E
Muñuzuri
A P
AP
Gómez-Gesteira
M
M
Plank
G
G
Schafferhofer
I
I
Pérez-Muñuzuri
V
V
Pérez-Villar
V
V
D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D004594:Electrophysiology; D006168:Guinea Pigs; D006329:Heart Conduction System / Q000502:physiology*; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D015398:Signal Transduction