title: [Chronic thromboembolic pulmonary hypertension: diagnostic impact of Multislice-CT and selective Pulmonary-DSA].
abstract: OBJECTIVE
  To evaluate the diagnostic impact of multislice-CT and selective pulmonary DSA in chronic thromboembolic pulmonary hypertension (CTEPH).
  
  
  METHODS
  994 vessel segments of 14 consecutive patients with CTEPH were investigated with multislice-CT (slice thickness 3 mm, collimation 2.5 mm, reconstruction intervall 2 mm) and selective pulmonary DSA (posterior-anterior, 45 degrees oblique, and lateral projection. Analysis was performed by 2 investigators independently for CT and DSA. Diagnostic criteria were occlusions and non-occlusive changes like webs and bands, irregularities of the vessel wall, diameter reduction and thromboembolic depositions at different levels from central pulmonary arteries to subsegmental arteries. Reference diagnosis was made by synopsis of CT and DSA by consensus.
  
  
  RESULTS
  Concerning patency CT and DSA showed concordant findings overall in 88.9 %, 92.9 % for segmental arteries and 85.4 % for subsegmental arteries. Concerning any thromboembolic changes, multislice-CT was significantly inferior to selective DSA (concordance 67.0 % overall, 70.4 % for segments and 63.6 % for subsegments). Non-occlusive changes of the vessels were significantly underdiagnosed by CT (concordance of CT versus DSA: 23.1 %).
  
  
  CONCLUSIONS
  Multislice-CT and selective pulmonary DSA are equivalent for diagnosis of vessel occlusions at the level of segmental and subsegmental arteries. However, for visualisation of the non-occlusive thromboembolic changes of the vessel wall selective pulmonary DSA is still superior compared to multislice-CT. Multislice-CT and selective pulmonary DSA are complementary tools for diagnosis and treatment planning of chronic thromboembolic pulmonary hypertension (CTEPH).
authors.affiliation: Klinik für Radiologie, Johannes Gutenberg-Universitat Mainz, Germany.
authors.forename: M B
authors.initials: MB
authors.lastname: Pitton
authors.forename: G
authors.initials: G
authors.lastname: Kemmerich
authors.forename: S
authors.initials: S
authors.lastname: Herber
authors.forename: F
authors.initials: F
authors.lastname: Schweden
authors.forename: E
authors.initials: E
authors.lastname: Mayer
authors.forename: M
authors.initials: M
authors.lastname: Thelen
mesh_terms: D015901:Angiography, Digital Subtraction / Q000379:methods*; D002908:Chronic Disease; D003627:Data Interpretation, Statistical; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging*; D011651:Pulmonary Artery / Q000000981:diagnostic imaging*; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*