title: Intracardiac thrombus in a patient with autoimmune hemolytic anemia leading to a diagnosis of antiphospholipid syndrome.
abstract: We report a case of antiphospholipid syndrome (APS) which presented with clinical and laboratory signs of an autoimmune hemolytic anemia (AHA), in the absence of manifestations typically related to APS. The diagnosis of APS was made only after the occurrence of a sudden severe heart failure due to an intraventricular thrombus requiring a surgical approach. An accurate thrombophilic screening is warranted also in patients with apparently idiopathic AHA.
authors.affiliation: Dipartimento di Biotecnologie Cellulari ed Ematologia, Università La Sapienza, Roma, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Latagliata
authors.forename: Francesca
authors.initials: F
authors.lastname: Celesti
authors.forename: Velia
authors.initials: V
authors.lastname: Bongarzoni
authors.forename: Giandomenico
authors.initials: G
authors.lastname: Di Nucci
authors.forename: Concetta
authors.initials: C
authors.lastname: Torromeo
authors.forename: Salvatore Giacomo
authors.initials: SG
authors.lastname: Morano
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Cimino
authors.forename: Giuliana
authors.initials: G
authors.lastname: Alimena
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology*; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000276:immunology; D003328:Coronary Thrombosis / Q000276:immunology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged