[Characteristics of activity of "fast" and "slow" Purkinje cells of the cerebellum].
In the guinea pig cerebellar cortex, three types of Purkinje cells were identified according to the properties of complex spikes: fast, intermediate, and slow cells. Fast Purkinje cells have following properties as compared with slow Purkinje cells: (i) salient components with short intervals in complex impulses (on the average, five components with a period of about 2 ms versus two components with a period of about 4 ms); (ii) a short duration of simple spikes (in the average, 2.13 +/- 0.53 ms versus 3.9 +/- 0.65 ms) and a quick restoration of their amplitude after preceding simple spikes (in the mean, 2.83 +/- 0.75 ms versus 11.0 +/- 2.82 ms); and (iii) a more pronounced rebound in the auto-correlation histogram of simple spikes (3.09 +/- 2.12 versus 1.45 +/- 0.36) and a short-latency excitation of simple spikes after complex spikes (2.81 +/- 1.64 versus 1.26 +/- 0.52). A decrease of interspike intervals in simple spike activity of all Purkinje cells was revealed (5.25 +/- 2.71 ms versus 9.71 +/- 3.48 ms in activity fragments without complex spikes). It is supposed that the properties of complex spikes depend on the type of Purkinje cells and may be one of the basic factors determining the interactions between the inputs of climbing and parallel fibers in Purkinje cells.
Podladchikova
L N
LN
Kogan Research Institute of Neurocybernetics, pr. Stachki 194/1, Rostov-na-Donu, 344090 Russia.
Bondar'
G G
GG
Dunin-Barkovskiĭ
V L
VL
D000818:Animals; D002525:Cerebellar Cortex / Q000166:cytology*; D004594:Electrophysiology; D006168:Guinea Pigs; D011689:Purkinje Cells / Q000502:physiology*