title: [Anaphylaxis after rocuronium: advantage of blood tests for early diagnosis].
abstract: A 56-year-old patient was scheduled for coronary artery bypass surgery, because of a severe coronary artery disease. Soon after induction of anaesthesia, he rapidly developed a cardiovascular collapse with bronchospasm and rash. Specific immunoglobulin E and tryptase measurements supported the diagnosis of grade III anaphylactic shock due to rocuronium bromide. A few days later, a general anaesthesia was administered without muscle relaxant and was uneventful.
authors.affiliation: Service d'anesthésie-réanimation, hôpital cardio-vasculaire et pneumologique Louis Pradel, BP Lyon Monchat, 69394 Lyon, France.
authors.forename: P
authors.initials: P
authors.lastname: Joseph
authors.forename: Y
authors.initials: Y
authors.lastname: Benoit
authors.forename: M
authors.initials: M
authors.lastname: Gressier
authors.forename: P
authors.initials: P
authors.lastname: Blanc
authors.forename: J J
authors.initials: JJ
authors.lastname: Lehot
mesh_terms: D000707:Anaphylaxis / Q000175:diagnosis* / Q000209:etiology*; D000732:Androstanols / Q000009:adverse effects*; D001026:Coronary Artery Bypass; D006403:Hematologic Tests; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007431:Intraoperative Complications / Q000175:diagnosis* / Q000209:etiology*; D008875:Middle Aged; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects*; D011229:Preanesthetic Medication; D000077123:Rocuronium; D012697:Serine Endopeptidases / Q000097:blood; D053802:Tryptases
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D007073:Immunoglobulin E; D012697:Serine Endopeptidases; D053802:Tryptases; D000077123:Rocuronium