Periungal hyperpigmentation induced by cisplatin.
A number of anticancer drugs are known to produce pigmentary changes affecting the skin or nails. Among them, cisplatin (cis-diamminedichloroplatinum)-induced hyperpigmentation has been described previously in only two cases. We describe an unusual case with hyperpigmentation confined to periungal areas of the hands and feet after treatment with cisplatin.
Kim
K J
KJ
Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, 388-1 Poongnap-dong, Songpa-gu, Seoul 138-736, Korea.
Chang
S E
SE
Choi
J H
JH
Sung
K J
KJ
Moon
K C
KC
Koh
J K
JK
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy; D002945:Cisplatin / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D005528:Foot; D006225:Hand; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D008113:Liver Neoplasms / Q000188:drug therapy; D008297:Male
D000970:Antineoplastic Agents; D002945:Cisplatin