title: The role of plant panallergens in sensitization to natural rubber latex.
abstract: Latex allergy represents an increasing occupational problem, mainly among healthcare workers. An association between latex allergy and hypersensitivity to some plant foods, particularly fruits (the latex-fruit syndrome), has been established. Class I chitinases with an N-terminal hevein-like domain from avocado, chestnut, banana and other foods, and latex hevein seem to be the allergens responsible for the cross-reactions involved in the latex-fruit syndrome. The potential role of other latex allergens, such as profilin, Hev b 5, Hev b 7 and beta-1,3-glucanases, in the co-sensitization to latex and plant foods is also discussed.
authors.affiliation: Unidad de Bioquímica, Departamento de Biotecnología, E.T.S. Ingenieros Agrónomos, Madrid, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Salcedo
authors.forename: A
authors.initials: A
authors.lastname: Diaz-Perales
authors.forename: R
authors.initials: R
authors.lastname: Sanchez-Monge
mesh_terms: D000485:Allergens / Q000276:immunology*; D000595:Amino Acid Sequence; D002688:Chitinases / Q000276:immunology / Q000378:metabolism; D003429:Cross Reactions; D005030:Ethylenes / Q000494:pharmacology; D005512:Food Hypersensitivity / Q000276:immunology; D006801:Humans; D007840:Latex / Q000276:immunology; D020315:Latex Hypersensitivity / Q000209:etiology*; D008969:Molecular Sequence Data; D010944:Plants / Q000276:immunology*
chemical_list: D000485:Allergens; D005030:Ethylenes; D007840:Latex; C036216:ethylene; D002688:Chitinases