title: Developmental evolution: Hox proteins ring the changes.
abstract: The evolution of body form is believed to involve changes in expression of developmental genes, largely through changes in cis-regulatory elements. Recent studies suggest that changes in the sequences of key developmental regulators, such as the Hox proteins, may also play an important role.
authors.affiliation: Institute of Molecular Biology and Biotechnology (IMBB-FORTH), Vassilika Vouton, 711 10 Iraklio Crete, Greece.
authors.forename: Anastasios
authors.initials: A
authors.lastname: Pavlopoulos
authors.forename: Michalis
authors.initials: M
authors.lastname: Averof
mesh_terms: D000818:Animals; D005075:Biological Evolution; D003445:Crustacea / Q000196:embryology / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000235:genetics* / Q000378:metabolism*; D007313:Insecta / Q000196:embryology / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D014157:Transcription Factors; C066177:Ubx protein, Drosophila; C117261:distal-less protein, insect