The inhibition of trypsin, plasmin, and thrombin by benzyl 4-guanidinobenzoate and 4'-nitrobenzyl 4-guanidinobenzoate.
The inhibition of the enzymes trypsin, plasmin, and thrombin by benzyl 4-guanidinobenzoate and 4'-nitrobenzyl 4-guanidinobenzoate is caused by acylation of the active site. Second order rate constants were determined.
Markwardt
F
F
Institute of Pharmacology and Toxicology, Medical Academy, Erfurt, GDR
Richter
M
M
Walsmann
P
P
Landmann
H
H