[Effect of nutritional state on cardiopulmonary exercise performance in patients with chronic obstructive pulmonary disease].
OBJECTIVE
To explore the effect of nutritional state on cardiopulmonary exercise performance of chronic obstructive pulmonary disease (COPD) patients.


METHODS
43 COPD patients and 20 healthy controls performed incremental cardiopulmonary exercise testing with cycle ergometer. Nutritional assessment and routine lung function studies were performed in all subjects before testing.


RESULTS
(1) Compared with the normally nourished COPD group, the malnourished group showed greater reduction in Wmax, VO(2)max, O(2)pulsemax, and AT (P < 0.05), whereas VO(2)/W/V(E) and DImax were higher in the malnourished group (P < 0.05). (2) IBW% was positively correlated with VO(2)max, Wmax, O(2)pulsemax, AT (r = 0.696, 0.432, 0.717, 0.822, P < 0.01), and negatively correlated with DImax and VO(2)/W/V(E) (r = -0.450, -0.640, P < 0.01) in COPD patients.


CONCLUSIONS
Malnutrition adversely affected muscle aerobic capacity and exercise tolerance in COPD patients.
Zhang
Xiaolei
X
Department of Pulmonary Disease, Second Hospital of China Medical University, Shenyang 110004, China.
Li
Shengqi
S
Zhao
Li
L
Chen
Yu
Y
Yang
Shuqin
S
Zhu
Lihua
L
D000328:Adult; D005080:Exercise Test; D017079:Exercise Tolerance; D005260:Female; D005541:Forced Expiratory Volume; D006321:Heart / Q000503:physiopathology*; D006334:Heart Function Tests; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009748:Nutrition Disorders / Q000503:physiopathology; D009752:Nutritional Status; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D011659:Pulmonary Gas Exchange; D012129:Respiratory Function Tests