From proinsulin-free insulin we obtained maximal purified insulin by means of preparative polyacrylamide electrophoresis (PADE). This substance appears in the analytical PADE as a uniform band and possesses glycine and phenylalanine as N-terminal amino acids. By use of the eviscerated rabbit as testing model, the product displays a higher hypoglycemic activity as compared with the Toronto standard.
Zühlke
H
H
Institut für Diabetes "Gerhardt Katsch", Bereich experimentelle Diabetesforschung, Karlsburg/Greifswald, DDR
Lippmann
H G.
HG
Wilke
W
W
Menzel
R
R
Hildmann
R
R