title: Analysis of the heat shock response of Neisseria meningitidis with cDNA- and oligonucleotide-based DNA microarrays.
abstract: Oligonucleotide- and cDNA-based microarrays comprising a subset of Neisseria meningitidis genes were assessed for study of the meningococcal heat shock response and found to be highly suitable for transcriptional profiling of N. meningitidis. Employing oligonucleotide arrays encompassing the entire genome of N. meningitidis, we analyzed the meningococcal heat shock response on a global scale and identified 55 heat shock-deregulated open reading frames (34 induced and 21 repressed).
authors.affiliation: Institute for Hygiene and Microbiology, University of Würzburg, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Guckenberger
authors.forename: Sebastian
authors.initials: S
authors.lastname: Kurz
authors.forename: Christian
authors.initials: C
authors.lastname: Aepinus
authors.forename: Stephanie
authors.initials: S
authors.lastname: Theiss
authors.forename: Sabine
authors.initials: S
authors.lastname: Haller
authors.forename: Thomas
authors.initials: T
authors.lastname: Leimbach
authors.forename: Ursula
authors.initials: U
authors.lastname: Panzner
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Weber
authors.forename: Hubert
authors.initials: H
authors.lastname: Paul
authors.forename: Alexandra
authors.initials: A
authors.lastname: Unkmeir
authors.forename: Matthias
authors.initials: M
authors.lastname: Frosch
authors.forename: Guido
authors.initials: G
authors.lastname: Dietrich
mesh_terms: D004269:DNA, Bacterial / Q000235:genetics; D018076:DNA, Complementary / Q000235:genetics; D018869:Heat-Shock Response; D009345:Neisseria meningitidis / Q000235:genetics / Q000502:physiology*; D020411:Oligonucleotide Array Sequence Analysis; D009841:Oligonucleotides / Q000235:genetics; D016366:Open Reading Frames
chemical_list: D004269:DNA, Bacterial; D018076:DNA, Complementary; D009841:Oligonucleotides