Calix[4]arenes linked to multiple bidentate N-donors: potential ligands for synthetic modeling of multinuclear metalloenzymes.
A series of calix[4]arenes incorporating three or four bidentate diamines or pyridylamines attached at the "upper rim" were synthesized via practical protocols. Proof of structure was obtained in one instance by X-ray crystallography. These molecules are designed for general use as ligands for the preparation of multinuclear active site models of metalloenzymes. [reaction: see text]
Spencer
Douglas J E
DJ
Department of Chemistry, Center for Metals in Biocatalysis, University of Minnesota, 207 Pleasant Street SE, Minneapolis, MN 55455, USA.
Johnson
Bryan J
BJ
Johnson
Brian J
BJ
Tolman
William B
WB
D000478:Alkylation; D047250:Calixarenes; D018360:Crystallography, X-Ray; D004798:Enzymes / Q000737:chemistry*; D008024:Ligands; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy; D008667:Metalloproteins / Q000737:chemistry*; D008958:Models, Molecular; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014019:Tissue Donors
D004798:Enzymes; D008024:Ligands; D046911:Macromolecular Substances; D008667:Metalloproteins; D047250:Calixarenes