Statistical analysis of ionic current fluctuations in membrane channels.
The statistical analysis of an ionic current signal recorded from a single channel of a biological membrane is presented. We find the main characteristics of the ionic current probability density, the closed- and open-state distributions, and the autocorrelation function of the current recordings by using procedures based on the kernel and tail estimators, the bootstrap methodology; and the Zipf plots. The results provide evidence for the non-Markovian character of the channel kinetics of the investigated data.
Mercik
S
S
Institute of Physics, Wroclaw University of Technology, 50-370 Wroclaw, Poland. mercik@rainbow.if.pwr.wroc.pl
Weron
K
K
Siwy
Z
Z
D000818:Animals; D002462:Cell Membrane / Q000502:physiology*; D006110:Grasshoppers / Q000502:physiology; D007473:Ion Channels / Q000502:physiology*; D007700:Kinetics; D008564:Membrane Potentials / Q000502:physiology; D008954:Models, Biological; D015233:Models, Statistical; D018485:Muscle Fibers, Skeletal / Q000502:physiology; D018408:Patch-Clamp Techniques / Q000379:methods; D011336:Probability; D013977:Tibia / Q000502:physiology; D013997:Time Factors
D007473:Ion Channels