title: [Primary lymphoma of the spleen: clinical analysis of 23 cases].
abstract: OBJECTIVE
  To investigate the best diagnostic and therapeutic method for primary lymphoma of the spleen.
  
  
  METHODS
  Clinicopathologic features of 23 patients treated from January 1956 to August 1999 were analyzed retrospectively.
  
  
  RESULTS
  All patients but one for exploration only (96%) underwent resection of the tumor. They accepted chemotherapy after operation. 23 patients were confirmed pathologically. B-cell type non-Hodgkin's lymphoma was noted in 21 patients and T-cell letion in 2. According to Ahman's staging, 9 patients belonged to stage I, 8 stage II, and 6 stage III. The 5-year survival rates were 50%, 40% and 16% respectively.
  
  
  CONCLUSIONS
  The diagnosis of splenic lymphoma is dependent mainly on B-ultrasound examination and CT scanning. Splenectomy combined with chemotherapy may provide optimum therapy for patients with splenic lymphoma.
authors.affiliation: Department of Hepatobiliary Surgery, Cancer Hospital, Tianjin Medical University, Tianjin 300060, China.
authors.forename: Rupeng
authors.initials: R
authors.lastname: Zhang
authors.forename: Dianchang
authors.initials: D
authors.lastname: Wang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Sun
authors.forename: Xishan
authors.initials: X
authors.lastname: Hao
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004358:Drug Therapy; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*