title: Technical advances and pitfalls on the way to human cloning.
abstract: There exists a widespread consensus that the cloning of human beings to term would be detrimental to both the mother and child and of little value to society. However, the ambition of a few organisations and the recent advances in cellular and molecular technologies that led to the cloning of Dolly the sheep, for example, have meant that such a procedure will be possible if not illegal in the near future. The science associated with the cloning technologies practiced in other mammalian species reported to date provide important advances in our understanding of how cells function during early developmental processes and commit themselves to specific developmental pathways. However, many technological insufficiencies remain. Both technological advances and several of the associated insufficiencies are outlined in this review.
authors.affiliation: Monash Institute of Reproduction and Development, Centre for Early Human Development, 27-31 Wright St, Clayton 3168, Australia.
authors.forename: Richard
authors.initials: R
authors.lastname: Mollard
authors.forename: Mark
authors.initials: M
authors.lastname: Denham
authors.forename: Alan
authors.initials: A
authors.lastname: Trounson
mesh_terms: D000818:Animals; D019976:Cloning, Organism / Q000379:methods*; D006801:Humans; D008928:Mitochondria / Q000378:metabolism; D053652:Nuclear Transfer Techniques; D009865:Oocytes / Q000502:physiology*; D016615:Telomere / Q000378:metabolism