title: [True aneurysm of the ascending aorta and/or aortic arch; determinants of late surgical outcome].
abstract: To identify significant predictors of late mortality, multivariate analysis were applied to the clinical outcome of 150 consecutive patients with true aneurysm of the ascending aorta and/or aortic arch operated between January, 1987 and December, 2000. Mean follow-up was 53.0 months with a total of 6,682 patient-months of follow-up. Multivariate analysis revealed that operation date (before December, 1996), presence of preoperative cerebrovascular disease, rupture and postoperative phrenic nerve palsy were independent determinants of late mortality. The overall 5-year and 10-year actuarial survival rates were 66.0% and 48.2%. The 5-year and 10-year event free rate of cardiovascular and/or cerebrovascular death were 88.9% and 71.7%. Preoperative evaluation of the brain, operation prior to aneurysm rupture and phrenic nerve protection during operation is necessary to improve long-term survival rate.
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Tohoku University, Sendai, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tabayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuru
authors.forename: H
authors.initials: H
authors.lastname: Akimoto
authors.forename: A
authors.initials: A
authors.lastname: Iguchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001011:Aorta / Q000601:surgery; D001013:Aorta, Thoracic / Q000601:surgery; D001014:Aortic Aneurysm / Q000401:mortality / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000401:mortality / Q000601:surgery; D019917:Blood Vessel Prosthesis Implantation / Q000401:mortality*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome