title: Multiple Bowen's disease of the fingers.
abstract: We describe herein a case of multiple Bowen's disease that developed on the left hand fingers of an 80-year-old male patient who had practiced as a gynecologist. PCR-based analysis indicated that the lesion contained human papillomavirus (HPV) type 18 DNA. Topical application of bleomycin and liquid nitrogen cryotherapy were effective in treating this case. After treatment, histopathologically no atypical cells were seen throughout the epidermis.
authors.affiliation: Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.
authors.forename: Miyuki
authors.initials: M
authors.lastname: Ota
authors.forename: Makoto
authors.initials: M
authors.lastname: Kawashima
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Mitsuishi
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000369:Aged, 80 and over; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D001761:Bleomycin / Q000008:administration & dosage; D001913:Bowen's Disease / Q000188:drug therapy / Q000473:pathology*; D005385:Fingers; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000903:Antibiotics, Antineoplastic; D001761:Bleomycin