title: [Group-specific antibodies against zearalenone and its metabolites and synthetic analogs].
abstract: Formation kinetics, specificity, and analytical potential of polyclonal antibodies raised in rabbits against BSA conjugates of carboxymethyloxime-zearalanone (CMO-ZAN) and carboxymethyloxime-zearalenone (CMO-ZEN). Preparation of the conjugates involved conversion of CMO-ZAN and CMO-ZEN into activated esters and carbodiimide condensation. Two versions of a group-specific enzyme immunoassay (for zearalenone/alpha-zearalenone and zearalanol/alpha-zearalanol) based on heterologous combination of solid-phase antigens are described (sensitivity, 0.01 ng/ml).
authors.affiliation: All-Russia Research Institute of Veterinary Sanitation, Hygiene, and Ecology, Russian Academy of Agricultural Sciences, Moscow, 123022 Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Burkin
authors.forename: G P
authors.initials: GP
authors.lastname: Kononenko
authors.forename: N A
authors.initials: NA
authors.lastname: Soboleva
mesh_terms: D000818:Animals; D000906:Antibodies / Q000097:blood / Q000276:immunology*; D000918:Antibody Specificity; D007124:Immunoenzyme Techniques / Q000379:methods; D008297:Male; D011817:Rabbits / Q000097:blood / Q000276:immunology*; D014614:Vaccines, Synthetic / Q000737:chemistry / Q000276:immunology; D015025:Zearalenone / Q000276:immunology* / Q000378:metabolism
chemical_list: D000906:Antibodies; D014614:Vaccines, Synthetic; D015025:Zearalenone