Walking the walk: migration and other common themes in blood and vascular development.
In this issue of Cell, a study by N. Cho and coworkers provides insight into the role of vascular endothelial growth factor (VEGF) signaling in Drosophila hematopoiesis. Their work suggests that an ancestral function of VEGF was to guide blood cell migration and highlights the conservation of at least one aspect of VEGF signaling during evolution.
Traver
David
D
Children's Hospital, Howard Hughes Medical Institute, Harvard University Medical School, Boston, MA 02115, USA.
Zon
Leonard I
LI
D000818:Animals; D001773:Blood Cells / Q000166:cytology; D001808:Blood Vessels / Q000166:cytology / Q000196:embryology; D002465:Cell Movement / Q000502:physiology; D016228:Endothelial Growth Factors / Q000502:physiology; D008222:Lymphokines / Q000502:physiology; D018919:Neovascularization, Physiologic / Q000502:physiology; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D016228:Endothelial Growth Factors; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors