A novel rearrangement to 1,2,4-triazolo[1,5-a]quinoxalines.
Reactions of benzyl bromide or benzyl cinnamate with N-(benzotriazol-1-ylmethyl)arylimidoyl chlorides (2a,b) in the presence of t-BuOK occur with opening of the benzotriazole ring affording 1,2,4-triazolo[1,5-a]quinoxalines (3a,b). A possible reaction mechanism is discussed.
Katritzky
Alan R
AR
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, 32611-7200, USA. katritzky@chem.ufl.edu
Huang
Tian-Bao
TB
Denisko
Olga V
OV
Steel
Peter J
PJ