The role of Helicobacter pylori in paediatrics.
Helicobacter pylori is a bacterium that colonizes the human stomach, especially during childhood. Although it has been studied intensively during the past decade, many controversies still exist on many important issues, including the clinical relevance of virulence factors, indications for treatment, recommended procedures for diagnosis and the typical symptom profile, among others. The lack of double-blind, placebo-controlled studies in children illustrates the paucity of hard scientific data, and is the major reason for differences in opinion. Therefore, the present review of literature published during the past 2 years raises many questions.
Vandenplas
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Academic Children's Hospital, Free University of Brussels, Brussels, Belgium. pedvsy@az.vub.ac.be
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D016481:Helicobacter Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D016480:Helicobacter pylori / Q000472:pathogenicity / Q000502:physiology*; D006801:Humans; D007223:Infant; D010372:Pediatrics