title: IL12B polymorphism and type 1 diabetes in the Italian population: a case-control study.
abstract: A polymorphism in the interleukin 12B gene was recently reported to be strongly associated with type 1 diabetes in 422 Australian and British families. We analyzed the same polymorphism in 470 Italian type 1 diabetic patients and 544 matched control subjects and found no evidence of association with the disease.
authors.affiliation: Institute of Cell Biology, CNR, Campus Buzzati-Traverso, Monterotondo, Rome, Italy. lnistico@ibc.rm.cnr.it
authors.forename: Lorenza
authors.initials: L
authors.lastname: Nisticò
authors.forename: Gabriele
authors.initials: G
authors.lastname: Giorgi
authors.forename: Mara
authors.initials: M
authors.lastname: Giordano
authors.forename: Andrea
authors.initials: A
authors.lastname: Galgani
authors.forename: Antonio
authors.initials: A
authors.lastname: Petrone
authors.forename: Sandra
authors.initials: S
authors.lastname: D'Alfonso
authors.forename: Massimo
authors.initials: M
authors.lastname: Federici
authors.forename: Umberto
authors.initials: U
authors.lastname: Di Mario
authors.forename: Paolo
authors.initials: P
authors.lastname: Pozzilli
authors.forename: Raffaella
authors.initials: R
authors.lastname: Buzzetti
authors.forename: Isabella
authors.initials: I
authors.lastname: Cascino
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006239:Haplotypes; D006801:Humans; D018664:Interleukin-12 / Q000235:genetics*; D007558:Italy / Q000453:epidemiology; D008297:Male; D011110:Polymorphism, Genetic; D012307:Risk Factors
chemical_list: D018664:Interleukin-12