title: The first stereoselective Ficini-Claisen rearrangement using chiral ynamides.
abstract: The first asymmetric Ficini-Claisen rearrangement using chiral ynamides is described. At relatively low temperatures, the Ficini-Claisen rearrangement can be efficiently promoted by p-nitrobenzenesulfonic acid leading to high diastereoselectivity for a range of different allylic alcohols and chiral ynamides. [reaction: see text]
authors.affiliation: Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
authors.forename: Jason A
authors.initials: JA
authors.lastname: Mulder
authors.forename: Richard P
authors.initials: RP
authors.lastname: Hsung
authors.forename: Michael O
authors.initials: MO
authors.lastname: Frederick
authors.forename: Michael R
authors.initials: MR
authors.lastname: Tracey
authors.forename: Craig A
authors.initials: CA
authors.lastname: Zificsak