Synthesis and spectroscopic properties of a new class of strongly fluorescent dipyrrinones.
A new, highly fluorescent (Phi(F) > or = 0.8) chromophore has been synthesized in one step from dipyrrinones by reaction with N,N-carbonyldiimidazole to form the 3H,5H-dipyrrolo[1,2-c:2',1'-f]pyrimidine-3,5-dione nucleus.
Brower
Justin O
JO
Department of Chemistry, University of Nevada, Reno, NV 89557-0020, USA.
Lightner
David A
DA
D001663:Bilirubin / Q000031:analogs & derivatives / Q000138:chemical synthesis; D002625:Chemistry, Organic / Q000379:methods; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D011744:Pyrimidinones / Q000138:chemical synthesis*; D011758:Pyrroles / Q000138:chemical synthesis*; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship
C462721:3H,5H-dipyrrolo(1,2-c - 2',1'-f)pyrimidine-3,5-dione; D005456:Fluorescent Dyes; D006575:Heterocyclic Compounds, 3-Ring; D011744:Pyrimidinones; D011758:Pyrroles; D001663:Bilirubin