title: Expression of super cervical ganglion-10 (SCG-10) mRNA in the monkey cerebral cortex during postnatal development.
abstract: We used Northern blot analysis to measure SCG10 mRNA expression in various areas of the monkey cerebral cortex during postnatal development. In all areas, SCG10 mRNA expression was highest immediately after birth, decreased sharply until postnatal day 70 (P70) and then decreased slowly until the adult stage. Expression levels were similar in all areas at all time points during development, including the adult stage. These findings confirm that axonal growth in the monkey cerebral cortex is most vigorous before or during the perinatal period, progresses similarly in all areas until P70, and continues at lower levels during late development.
authors.affiliation: Systems Neuroscience Group, Neuroscience Research Institute, National Institute of Advanced Industrial Science and Technology, Umezono, Tsukuba, Ibaraki 305-8568, Japan. t.oishi@aist.go.jp
authors.forename: Takao
authors.initials: T
authors.lastname: Oishi
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Higo
authors.forename: Keiji
authors.initials: K
authors.lastname: Matsuda
authors.forename: Motoharu
authors.initials: M
authors.lastname: Hayashi
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D002540:Cerebral Cortex / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*; D019922:GAP-43 Protein / Q000235:genetics / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000235:genetics; D008251:Macaca / Q000254:growth & development* / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D009414:Nerve Growth Factors / Q000235:genetics*; D016501:Neurites / Q000378:metabolism; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D017397:Prefrontal Cortex / Q000166:cytology / Q000254:growth & development / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism*; D013003:Somatosensory Cortex / Q000166:cytology / Q000254:growth & development / Q000378:metabolism; D014793:Visual Cortex / Q000166:cytology / Q000254:growth & development / Q000378:metabolism
chemical_list: D019922:GAP-43 Protein; D009414:Nerve Growth Factors; D012333:RNA, Messenger; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases