[Effect of intracellular ATP on La(3+)-induced aggregation and fusion of human erythrocytes].
The influence of intracellular ATP level on the aggregation and fusion of human erythrocytes, induced by La3+ in the concentration range 20-330 microM was studied. The aggregation of intact red blood cells differs from that of cells with increased and decreased contents of ATP. Incubation of erythrocyte aggregates at 37 degrees C did not lead to cell fusion. At the same time, incubation of erythrocyte aggregates with decreased and increased ATP contents in the presence of La3+ induced a pronounced cell fusion.
Sheremet'ev
Iu A
IuA
Nizhnii Novgorod State Agricultural Academy, pr. Gagarina 97, Nizhnii Novgorod, 603107 Russia.
Sheremet'eva
A V
AV
D000255:Adenosine Triphosphate / Q000378:metabolism*; D002449:Cell Aggregation / Q000187:drug effects; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000502:physiology; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology; D006801:Humans; D007811:Lanthanum / Q000494:pharmacology*; D008561:Membrane Fusion / Q000187:drug effects
D007811:Lanthanum; D000255:Adenosine Triphosphate