title: Pregnancy and delivery in a patient with metastatic embryonal sarcoma of the liver.
abstract: BACKGROUND
  Embryonal sarcoma of the liver is a rare undifferentiated mesenchymal neoplasm with a grave prognosis.
  
  
  METHODS
  We report a spontaneous uneventful pregnancy in a young woman with recurrent metastatic embryonal sarcoma of the liver after hepatectomy (twice) and radiochemotherapy. The patient chose to continue pregnancy despite her general condition and possible hazards to maternal and fetal well-being. She gave birth to a full-term healthy infant. Her disease recurred shortly after the delivery.
  
  
  CONCLUSIONS
  According to a computerized search of the National Library of Medicine database, from 1966 to present, using the search terms "embryonal (or undifferentiated) sarcoma" and "liver" without language restrictions, this is the first reported case of pregnancy and delivery in a patient with embryonal sarcoma of the liver. It illustrates the clinical and ethical dilemmas associated with this complicated condition.
authors.affiliation: Department of Obstetrics and Gynecology, Oncology, Pathology, Hadassah University Hospital, Ein-Kerem, Jerusalem, Israel. yoels@md.huji.ac.il
authors.forename: Yoel
authors.initials: Y
authors.lastname: Shufaro
authors.forename: Beatrice
authors.initials: B
authors.lastname: Uzieli
authors.forename: Orit
authors.initials: O
authors.lastname: Pappo
authors.forename: Yoram
authors.initials: Y
authors.lastname: Abramov
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000628:therapy*; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000628:therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000628:therapy*; D011256:Pregnancy Outcome; D012509:Sarcoma / Q000473:pathology* / Q000628:therapy*; D012888:Skull Neoplasms / Q000556:secondary* / Q000628:therapy*