title: An elderly patient with DCIS of the breast effectively treated with toremifene alone.
abstract: An elderly patient with breast cancer received toremifene monotherapy for one year, and about 60% tumor remission rate was obtained. Since viability of the residual tumor was suspected on ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI), lumpectomy was performed under local anesthesia. The histopathological diagnosis was ductal carcinoma in situ (DCIS). The patient did not undergo axillary lymph node dissection or systemic chemotherapy. The patient is alive without disease under postoperative radiotherapy and toremifene treatment. Toremifene monotherapy and/or preoperative adjuvant therapy with toremifene alone may be useful methods for elderly patients with breast cancer considering the patients' quality of life.
authors.affiliation: Department of Radiology, Hosogi Hospital, Kochi 780-8535, Japan.
authors.forename: Norihiko
authors.initials: N
authors.lastname: Hamada
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Ogawa
authors.forename: Akihito
authors.initials: A
authors.lastname: Nishioka
authors.forename: Shinji
authors.initials: S
authors.lastname: Kariya
authors.forename: Masako
authors.initials: M
authors.lastname: Terashima
authors.forename: Shoji
authors.initials: S
authors.lastname: Yoshida
authors.forename: Yohsuke
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Taisuke
authors.initials: T
authors.lastname: Inomata
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011788:Quality of Life; D014057:Tomography, X-Ray Computed; D017312:Toremifene / Q000627:therapeutic use*; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D017312:Toremifene