title: [Transgenic cattle constitute a breakthrough in production of innovative medicine. From milk to medicine].
abstract: The continuously increasing demand for biomolecules, e.g. human proteins, for applications in human health care, is one of the main driving forces for the development of safe, large-scale production systems. One very promising approach is the production of biomolecules in the milk of transgenic cattle. By using nuclear transfer technology, transgenic cattle can be generated in a very safe and efficient manner, thereby offering a significant time reduction when compared to conventional breeding methods. As a result, that the transgenic cattle platform offers an efficient, safe and cost-effective method for producing large amounts of biopharmaceuticals, which is essential to the development of innovative health care products.
authors.affiliation: Pharming Technologies B.V., Leiden.
authors.forename: M
authors.initials: M
authors.lastname: Salaheddine
authors.forename: E
authors.initials: E
authors.lastname: Thole
authors.forename: M
authors.initials: M
authors.lastname: Brink
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D030801:Animals, Genetically Modified; D001702:Biopharmaceutics; D002417:Cattle; D005260:Female; D018014:Gene Transfer Techniques; D008297:Male; D008892:Milk / Q000737:chemistry*; D008894:Milk Proteins; D053652:Nuclear Transfer Techniques; D011994:Recombinant Proteins / Q000096:biosynthesis*; D012449:Safety
chemical_list: D008894:Milk Proteins; D011994:Recombinant Proteins