title: [Cerebral venous thrombosis and factor V Leiden mutation].
abstract: OBJECTIVE
  To investigate the relationship between factor V Leiden mutation and cerebral venous thrombosis in China.
  
  
  METHODS
  20 patients and 50 controls of Chinese origin were studied by polymerase chain reaction followed by Mnl I restriction enzyme analysis.
  
  
  RESULTS
  The PCR products of all the people supervised were digested to three segments with the length of 37 bp, 67 bp, and 116 bp. No factor V Leiden mutation was found in any subjects.
  
  
  CONCLUSIONS
  Factor V Leiden mutation is not a crucial risk factor of cerebral venous thrombosis.
authors.affiliation: Department of Neurology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Meng
authors.forename: Chuanqiang
authors.initials: C
authors.lastname: Pu
mesh_terms: D000328:Adult; D002539:Cerebral Arterial Diseases / Q000235:genetics*; D005165:Factor V / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D012307:Risk Factors; D020246:Venous Thrombosis / Q000235:genetics*
chemical_list: C095381:factor V Leiden; D005165:Factor V