title: Pyloric gland-type tubular adenoma superimposed on intraductal papillary mucinous tumor of the pancreas. Pyloric gland adenoma of the pancreas.
abstract: We report a rare case of pyloric gland-type tubular adenoma of the main pancreatic duct. It was a grossly visible polypoid nodule and was composed of closely packed pyloric-type glands. This adenoma was present within an intraductal papillary mucinous adenoma (IPMA). In this IPMA lesion, aggregations of pyloric-type glands were occasionally observed, and most of the cells including ductal lining cells expressed pyloric gland-type mucin. The IPMA of the present case showed more extensive pyloric gland metaplasia or differentiation than commonly noted in IPMAs. We consider this pyloric gland-type tubular adenoma to be derived from a selective growth of IPMA cells showing pyloric gland metaplasia.
authors.affiliation: Department of Pathology, Yamagata University School of Medecine, Yamagata, 990-9585, Japan, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Kato
authors.affiliation: Department of Pathology, Yamagata University School of Medecine, Yamagata, 990-9585, Japan, Japan.
authors.forename: Sunao
authors.initials: S
authors.lastname: Akiyama
authors.affiliation: Department of Pathology, Yamagata University School of Medecine, Yamagata, 990-9585, Japan, Japan.
authors.forename: Teiichi
authors.initials: T
authors.lastname: Motoyama
mesh_terms: D000236:Adenoma / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D000368:Aged; D000911:Antibodies, Monoclonal; D003208:Concanavalin A / Q000032:analysis; D004273:DNA, Neoplasm / Q000032:analysis; D005088:Exocrine Glands / Q000378:metabolism / Q000473:pathology; D042882:Gallstones / Q000209:etiology / Q000473:pathology / Q000601:surgery; D005753:Gastric Mucosa / Q000378:metabolism / Q000473:pathology*; D011905:Genes, ras; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008679:Metaplasia; D009077:Mucins / Q000032:analysis / Q000276:immunology / Q000378:metabolism; D009154:Mutation; D016609:Neoplasms, Second Primary / Q000378:metabolism / Q000473:pathology*; D010183:Pancreatic Ducts / Q000378:metabolism / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D016133:Polymerase Chain Reaction
chemical_list: D000911:Antibodies, Monoclonal; D004273:DNA, Neoplasm; D009077:Mucins; D003208:Concanavalin A