title: Cohort study of near-miss maternal mortality and subsequent reproductive outcome.
abstract: OBJECTIVE
  To determine the aetiology and outcome of near-miss mortality in obstetrical patients and the subsequent reproductive outcome where fertility is conserved.
  
  
  METHODS
  Retrospective cohort study of 51,576 women delivered at a University teaching hospital of whom 50 required transfer for critical care.
  
  
  RESULTS
  Over the 12 year study period 1988-1999, 50 women required transfer for intensive care (0.97/1000) and there were three maternal deaths (5.8/100,000). The main indications for transfer were hypertensive disease (32%), haemorrhage (24%) and maternal cardiac disease (24%). The perinatal mortality rate was 14%. Thirty two women conserved their fertility potential and 16 had subsequent healthy liveborn children.
  
  
  CONCLUSIONS
  This study of near-miss maternal mortality reminds us of the need for continuing vigilance in the provision of obstetrical care. The successful reproductive outcome highlights the resilience of many women to adverse events in pregnancy but the high loss of fertility potential reflects the physical and psychological morbidity incurred.
authors.affiliation: Division of Obstetrics and Gynaecology, St. Michael's Hospital, University of Bristol, Southwell St., Bristol BS2 8EG, UK. d.j.murphy@bristol.ac.uk
authors.forename: Deirdre J
authors.initials: DJ
authors.lastname: Murphy
authors.forename: Pauline
authors.initials: P
authors.lastname: Charlett
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003422:Critical Care; D005260:Female; D005298:Fertility; D006331:Heart Diseases / Q000150:complications / Q000628:therapy; D006470:Hemorrhage / Q000150:complications / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000628:therapy; D007226:Infant Mortality; D007231:Infant, Newborn; D008428:Maternal Mortality; D011247:Pregnancy; D011248:Pregnancy Complications / Q000401:mortality*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome