Rhabdomyolysis with acute renal failure probably related to the interaction of atorvastatin and delavirdine.
Castro
Jose G
JG
Gutierrez
Luis
L
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis / Q000201:enzymology; D019380:Anti-HIV Agents / Q000009:adverse effects* / Q000493:pharmacokinetics; D000924:Anticholesteremic Agents / Q000009:adverse effects* / Q000493:pharmacokinetics; D000069059:Atorvastatin; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects*; D020008:Delavirdine / Q000009:adverse effects* / Q000493:pharmacokinetics; D004347:Drug Interactions; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy; D006538:Heptanoic Acids / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects* / Q000493:pharmacokinetics; D006937:Hypercholesterolemia / Q000150:complications / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D006899:Mixed Function Oxygenases / Q000187:drug effects*; D011758:Pyrroles / Q000009:adverse effects* / Q000493:pharmacokinetics; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000175:diagnosis / Q000201:enzymology
D019380:Anti-HIV Agents; D000924:Anticholesteremic Agents; D006538:Heptanoic Acids; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011758:Pyrroles; D003577:Cytochrome P-450 Enzyme System; D000069059:Atorvastatin; D020008:Delavirdine; D006899:Mixed Function Oxygenases; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A