title: Site-specific recombination with the chromosomal tRNA(Leu) gene by the large conjugative Haemophilus resistance plasmid.
abstract: Characterization of the sequences involved in recombination of the Haemophilus plasmid p1056 with the Haemophilus influenzae chromosome produced evidence indicating site-specific recombination with chromosomal tRNA(Leu). attP sequences identical to those of p1056 were found in six plasmids of diverse origin, suggesting that a family of Haemophilus plasmids recombines with chromosomal tRNA(Leu).
authors.affiliation: Interdepartmental Academic Unit of Infectious Diseases and Microbiology, Oxford University, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.
authors.forename: Ioanna D
authors.initials: ID
authors.lastname: Dimopoulou
authors.forename: Joanne E
authors.initials: JE
authors.lastname: Russell
authors.forename: Zaini
authors.initials: Z
authors.lastname: Mohd-Zain
authors.forename: Rebecca
authors.initials: R
authors.lastname: Herbert
authors.forename: Derrick W
authors.initials: DW
authors.lastname: Crook
mesh_terms: D001435:Bacteriophages / Q000235:genetics; D002876:Chromosomes, Bacterial; D003001:Cloning, Molecular; D003227:Conjugation, Genetic; D024881:Drug Resistance, Bacterial / Q000235:genetics; D006193:Haemophilus influenzae / Q000187:drug effects* / Q000235:genetics / Q000821:virology; D006801:Humans; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics*; D012356:RNA, Transfer, Leu / Q000235:genetics*; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA
chemical_list: D012356:RNA, Transfer, Leu