title: [Intraocular high pressure in thyroid-associated orbitopathy: physiopathological mechanisms, diagnosis, and management. Three case reports].
abstract: OBJECTIVE
  To determine the mechanisms and treatment of ocular hypertension in patients with thyroid-associated orbitopathy and to differenciate it from glaucomatous damage.
  
  
  METHODS
  Three case reports.
  
  
  METHODS
  Retrospective review of clinical findings, course, and treatment of the three patients.
  
  
  RESULTS
  Elevated intraocular pressure in thyroid-associated orbitopathy observed in the three cases may involve different physiopathological abnormalities such as disturbances of venous circulation, compression by infiltrative muscles, and long corticosteroid use. In the first two cases, defects demonstrated in the perimetry are in consistent with glaucomatous damage. In the third case, visual field abnormalities may be compatible with a glaucomatous disease, but all defects resolved after therapy. Treatement was of the greatest difficulty for the three cases, associating antiglaucomatous medication, steroids, orbital radiotherapy, orbital decompression and extraocular muscle surgery. Intraocular pressure was controlled in all cases.
  
  
  CONCLUSIONS
  Elevated intraocular pressure in thyroid-associated orbitopathy is distinguished from glaucomatous disease by its physiopathological mechanisms, clinical course, visual field defects, and treatment. The management of this hypertension is closely related to the treatment of dysthyroid orbitopathy.
authors.affiliation: Fondation ophtalmologique Adolphe de Rothschild, Paris, France.
authors.forename: H
authors.initials: H
authors.lastname: Ben Ayed
authors.forename: M
authors.initials: M
authors.lastname: Hamedani
authors.forename: C
authors.initials: C
authors.lastname: Bok
authors.forename: P
authors.initials: P
authors.lastname: Barraco
authors.forename: A
authors.initials: A
authors.lastname: Oubaaz
authors.forename: S
authors.initials: S
authors.lastname: Morax
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D012189:Retrospective Studies; D013959:Thyroid Diseases / Q000150:complications*