title: Post-exposure rabies treatment in pigs.
abstract: A rabid dog invaded a Thai pig farm and severely mauled 11 adult pigs. This offered an opportunity to study efficacy of a human type post-exposure vaccine regimen with and without rabies immunoglobulin. A commercial veterinary tissue culture rabies vaccine and equine rabies immune globulin were used. All pigs survived for 1 year following the exposure. All animals developed detectable rabies neutralizing antibodies on day 7 and levels over 0.5IU/ml on day 14. This small study suggests that post-exposure rabies treatment using a proven human regimen, applied to valuable farm animals, can be safe and effective.
authors.affiliation: Queen Saovabha Memorial Institute, Thai Red Cross Society, 1871 Rama IV Road, Bangkok 10330, Thailand.
authors.forename: Channarong
authors.initials: C
authors.lastname: Mitmoonpitak
authors.forename: Sukunya
authors.initials: S
authors.lastname: Limusanno
authors.forename: Pakamatz
authors.initials: P
authors.lastname: Khawplod
authors.forename: Veera
authors.initials: V
authors.lastname: Tepsumethanon
authors.forename: Henry
authors.initials: H
authors.lastname: Wilde
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D004285:Dogs; D011818:Rabies / Q000628:therapy / Q000662:veterinary*; D011819:Rabies Vaccines / Q000627:therapeutic use; D013552:Swine; D013553:Swine Diseases / Q000628:therapy*
chemical_list: D000914:Antibodies, Viral; D011819:Rabies Vaccines