Integrating functions at the kinetochore.
Kinetochore components have catalytic as well as structural activities. New evidence illustrates how these proteins integrate spindle morphogenesis with regulation of the timing and accuracy of chromosome segregation.
Shimoda
Soni L
SL
Department of Biology and Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Solomon
Frank
F
D000705:Anaphase / Q000502:physiology; D000818:Animals; D020090:Chromosome Segregation / Q000502:physiology; D006801:Humans; D018386:Kinetochores / Q000502:physiology*; D046911:Macromolecular Substances; D008870:Microtubules / Q000502:physiology; D008938:Mitosis / Q000502:physiology*; D008941:Spindle Apparatus / Q000502:physiology*
D046911:Macromolecular Substances