Intracardiac thrombus in a patient with autoimmune hemolytic anemia leading to a diagnosis of antiphospholipid syndrome.
We report a case of antiphospholipid syndrome (APS) which presented with clinical and laboratory signs of an autoimmune hemolytic anemia (AHA), in the absence of manifestations typically related to APS. The diagnosis of APS was made only after the occurrence of a sudden severe heart failure due to an intraventricular thrombus requiring a surgical approach. An accurate thrombophilic screening is warranted also in patients with apparently idiopathic AHA.
Latagliata
Roberto
R
Dipartimento di Biotecnologie Cellulari ed Ematologia, Università La Sapienza, Roma, Italy.
Celesti
Francesca
F
Bongarzoni
Velia
V
Di Nucci
Giandomenico
G
Torromeo
Concetta
C
Morano
Salvatore Giacomo
SG
Cimino
Giuseppe
G
Alimena
Giuliana
G
D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology*; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000276:immunology; D003328:Coronary Thrombosis / Q000276:immunology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged