title: A study on clinical profile of falciparum malaria in a tertiary care hospital in south India.
abstract: Malaria continues to be a major problem in tropical countries. To study the clinical features and complications of malaria in a tertiary care hospital in south India, records of 183 patients were analysed. Among 86 patients with P. falciparum and mixed infection, 24 (28 per cent) had cerebral malaria and 32 (37 per cent) had hyperbilirubinemia. Twenty-three out of 32 (72 per cent) patients with jaundice had direct hyperbilirubinemia and elevated liver enzymes suggesting hepatocellular damage. Mortality of the order of 10 per cent was seen only in P. falciparum malaria. High incidence of hepatic involvement and hepatorenal failure were the unusual features observed in the study.
authors.affiliation: Department of Clinical Pathology, Christian Medical College and Hospital, Vellore-632 004, India.
authors.forename: V K
authors.initials: VK
authors.lastname: Harris
authors.forename: V S
authors.initials: VS
authors.lastname: Richard
authors.forename: E
authors.initials: E
authors.lastname: Mathai
authors.forename: U
authors.initials: U
authors.lastname: Sitaram
authors.forename: K V
authors.initials: KV
authors.lastname: Kumar
authors.forename: A M
authors.initials: AM
authors.lastname: Cherian
authors.forename: S M
authors.initials: SM
authors.lastname: Amelia
authors.forename: G
authors.initials: G
authors.lastname: Anand
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006505:Hepatitis / Q000150:complications*; D006801:Humans; D006932:Hyperbilirubinemia / Q000150:complications*; D007194:India; D007565:Jaundice / Q000150:complications*; D016779:Malaria, Cerebral / Q000150:complications* / Q000401:mortality; D016778:Malaria, Falciparum / Q000150:complications*; D016780:Malaria, Vivax / Q000150:complications*; D008297:Male; D008499:Medical Records