Innovative pharmacologic approaches to cardiopulmonary resuscitation.
The survival rate of patients undergoing cardiopulmonary resuscitation is 5 to 15%. New cardiopulmonary resuscitation treatment approaches under investigation include the use of vasopressin as a vasopressor, amiodarone for the treatment of ventricular tachyarrhythmias, and adenosine antagonists (i.e., theophylline) for bradyasystolic rhythms. More innovative approaches include the use of thyroid hormone and endothelin.
Kelsch
T
T
Department of Medicine, New York Medical College, Westchester County Medical Center, Valhalla, New York, USA.
Kikuchi
K
K
Vahdat
S
S
Frishman
W H
WH
D000572:American Heart Association; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000592:standards / Q000627:therapeutic use*; D016887:Cardiopulmonary Resuscitation / Q000592:standards; D002318:Cardiovascular Diseases / Q000628:therapy; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy / Q000592:standards; D019332:Endothelin-1 / Q000627:therapeutic use; D006801:Humans; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D014486:United States Food and Drug Administration
D000889:Anti-Arrhythmia Agents; D019332:Endothelin-1