Bipseudophakia: clinicopathological correlation of a dropped lens.
OBJECTIVE
To examine postmortem human globes containing an anterior chamber and a posterior chamber intraocular lens (IOL).


METHODS
Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Charleston, South Carolina, USA.


METHODS
The globes were sectioned at the equator, and the anterior and posterior segments were macroscopically examined. Gross photographs were taken using the Miyake-Apple posterior photographic technique. Histological sections were cut and stained with hematoxylin and eosin, periodic acid-Schiff, and Masson's trichrome.


RESULTS
Histopathological findings included a large Soemmering's ring, a tear in the posterior capsule, 1 haptic of the anterior chamber IOL displaced into the iridectomy, thin and atrophic corneal epithelium, separation of Bowman's layer and stroma by fibrovascular tissue, and atrophy of the retinal ganglion cell layer and nerve fiber layer.


CONCLUSIONS
In cases in which secondary IOL implantation is indicated, removing the dislocated IOL appears to be a reasonable choice.
Izak
Andrea M
AM
Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA.
Apple
David J
DJ
Werner
Liliana
L
Trivedi
Rupal H
RH
Pandey
Suresh K
SK
Macky
Tamer A
TA
Schmidbauer
Josef M
JM
Marsh
Peter
P
D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000473:pathology*; D005548:Foreign-Body Migration / Q000209:etiology / Q000473:pathology*; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D011475:Prosthesis Failure; D019591:Pseudophakia / Q000150:complications / Q000473:pathology*; D012086:Reoperation; D014822:Vitreous Body / Q000473:pathology*