title: Carotid-cavernous sinus fistulae in craniofacial trauma: classification and treatment.
abstract: Carotid-cavernous sinus fistulae (CCF) represent pathological communications between the intracavernous internal carotid artery and the cavernous venous sinus. Although trauma is the most common cause of high flow carotid cavernous fistulae, they are relatively uncommon in patients sustaining craniofacial trauma. Nevertheless, CCF require early diagnosis and rapid and effective treatment in order to prevent severe and significant morbidity. Clinical presentation may include pulsatile proptosis, ocular and orbital erythema, chemosis, diplopia, headaches, and visual loss. Cerebral angiography is currently the definitive diagnostic study. Obliteration of the fistula by endovascular techniques is the current mainstay treatment, and direct surgery is reserved for cases that have failed endovascular therapy. This article reviews clinical features, pertinent anatomy, and therapeutic approaches to carotid-cavernous sinus fistulae.
authors.affiliation: Division of Neurological Surgery, N521, University of Missouri Health Sciences Center, One Hospital Drive, Columbia, MO 65212, USA.
authors.forename: D F
authors.initials: DF
authors.lastname: Jimenez
authors.forename: S R
authors.initials: SR
authors.lastname: Gibbs
mesh_terms: D001164:Arteriovenous Fistula / Q000145:classification* / Q000628:therapy; D002343:Carotid Artery, Internal; D002426:Cavernous Sinus; D003229:Conjunctival Diseases / Q000209:etiology; D004172:Diplopia / Q000209:etiology; D004487:Edema / Q000209:etiology; D004621:Embolization, Therapeutic / Q000295:instrumentation / Q000379:methods; D004890:Erythema / Q000209:etiology; D005094:Exophthalmos / Q000209:etiology; D005151:Facial Injuries / Q000150:complications*; D006261:Headache / Q000209:etiology; D006801:Humans; D012886:Skull / Q000293:injuries*; D014786:Vision Disorders / Q000209:etiology