Gastric carcinoma resembling submucosal tumor.
Acase of stomach carcinoma showing features of submucosal tumor is reported. The patient was a 50-year-old man presenting with hematemesis. Endoscopic examination was performed and revealed a submucosal tumor-like lesion with central ulceration in the fornix of the stomach. The biopsy specimen from this lesion showed poorly differentiated adenocarcinoma, and surgery was performed. The tumor, measuring 3.5 x 2.7 cm in size, invaded to the muscularis propria with proliferation of the interstitial connective tissue and lymphoid follicles consisting mainly of B lymphocytes in the submucosal layer. In situ hybridization of tumor tissue for Epstein-Barr virus (EBV)-encoded small RNA1 as target revealed negative results. In stomach carcinoma simulating submucosal tumor, as in this patient, preoperative diagnosis is important to plan treatment strategies.
Umehara
Yasuhiko
Y
Department of Surgery, Fujinomiya City General Hospital, 3-1 Nishikicho, Fujinomiya, Shizuoka 418-0076, Japan.
Kimura
Taizo
T
Okubo
Tadatoshi
T
Sano
Yoshihiko
Y
Nakai
Katsuhiko
K
Oi
Satoshi
S
Higashi
Yukihiro
Y
Funai
Kazuhito
K