title: [Malignant tumor and hyperfibrinogenemia].
abstract: OBJECTIVE
  To investigate the blood fibrinogen (FIB) content before and after chemotherapy or radiotherapy in 43 malignant tumor patients.
  
  
  METHODS
  COULTER ACL-200 automated coagulation analyzer was used in monitoring FIB in the patients.
  
  
  RESULTS
  The FIB content was significantly higher in malignant tumor patients than that in benign disease patients. Significant reduction was observed after treatment which became elevated again when there was recurrence or metastasis.
  
  
  CONCLUSIONS
  Assessment of FIB not only helps to diagnose cancers but evaluate the therapeutic effect and prognosis also.
authors.affiliation: Department of Clinical Laboratory, Beijing Cancer Hospital, Beijing 100036, China.
authors.forename: Xiuqiao
authors.initials: X
authors.lastname: Liu
authors.forename: Shujuan
authors.initials: S
authors.lastname: Wang
authors.forename: Zhenru
authors.initials: Z
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.forename: Weihui
authors.initials: W
authors.lastname: Wan
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood* / Q000532:radiotherapy; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor; D005340:Fibrinogen