title: Mediated biosensors.
abstract: Direct electrode transfer between enzyme and the electrode in biosensors requires high efficiency therefore, synthetic replacement for oxygen led to the development of enzyme mediators and modified electrodes in biosensor fabrication. In this context, a number of electron acceptors and complexes have been used. Present paper gives an overview of various methodologies involved in the mediated systems, their merits and wide applications.
authors.affiliation: Biomolecular Electronics and Conducting Polymer Research Group, National Physical Laboratory, Dr. K.S. Krishnan Marg, New Delhi 110 012, India. achaubey@csnpl.ren.nic.in
authors.forename: Asha
authors.initials: A
authors.lastname: Chaubey
authors.forename: B D
authors.initials: BD
authors.lastname: Malhotra
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D002384:Catalysis; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods; D004566:Electrodes; D004579:Electron Transport; D004800:Enzymes, Immobilized / Q000737:chemistry* / Q000378:metabolism*; D008956:Models, Chemical; D010084:Oxidation-Reduction
chemical_list: D004800:Enzymes, Immobilized