title: Gastroduodenal intussusception due to Peutz-Jeghers syndrome in infancy.
abstract: A case of Peutz-Jeghers Syndrome (PJS) presenting in infancy with gastric-outlet obstruction is described. PJS may become symptomatic at any age and should be suspected when there are obstructive symptoms or gastrointestinal blood loss in a baby with a positive family history. Contrast studies and endoscopy are useful in diagnosis and surveillance. Treatment requires a combination of endoscopy and laparotomy/laparoscopy. Because of the reported cancer risk, we recommend surveillance from the age of diagnosis.
authors.affiliation: Department of Surgery, Prince of Wales Hospital, High Street, Randwick 2031, Australia.
authors.forename: Fred
authors.initials: F
authors.lastname: Boseto
authors.forename: Edward
authors.initials: E
authors.lastname: Shi
authors.forename: John
authors.initials: J
authors.lastname: Mitchell
authors.forename: John
authors.initials: J
authors.lastname: Preddy
authors.forename: Susan
authors.initials: S
authors.lastname: Adams
mesh_terms: D004380:Duodenal Obstruction / Q000209:etiology* / Q000601:surgery; D005260:Female; D017219:Gastric Outlet Obstruction / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007223:Infant; D007443:Intussusception / Q000209:etiology* / Q000601:surgery; D010580:Peutz-Jeghers Syndrome / Q000150:complications*