Infections in solid organ transplant recipients.
Studies published within the past year have highlighted the potential morbidity associated with polyomaviruses and novel herpesviruses (e.g. human herpesvirus-6, 7 and -8). Although antiviral therapy has not been shown to be effective for polyomaviruses, attempts at management of human herpesvirus-6 and -8 infections with antiviral agents appear anecdotally promising. Bacterial infections remain the most frequently occurring infections in transplant recipients, and the challenges that face the transplant care providers pertain to a striking rise in antimicrobial resistance among these pathogens. Effective prophylaxis and management of invasive mould infections continue to be the focus of clinical studies, but an optimal approach remains elusive.
Singh
Nina
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Infectious Disease Section, VA Medical Center, Pittsburgh, Pennsylvania, USA.