[Risk factors for the acquisition of Pseudomonas aeruginosa in a surgical intensive care unit].
OBJECTIVE
To investigate the risk factors for the acquisition (infection and/or colonization) of Pseudomonas aeruginosa, which is frequently associated with nosocomial infections, in a surgical intensive care unit in Dijon.


METHODS
A retrospective case-control study was performed on 57 cases matching with 114 controls, between December 1996 and February 1999. The statistical method used was a conditional multiple logistic regression model.


RESULTS
Three groups of variables were studied (patient characteristics--invasive procedures--previous administration of antibiotics). The multiple logistic regression analysis confirmed 3 risk factors: duration of sedation, infection with another bacteria and cranio-encephalic trauma. These factors are commonly involved in nosocomial infections.


CONCLUSIONS
This study confirms the interest of infection control measures and the prevention of nosocomial infections, especially in cranio-encephalic trauma. The hypothetical relationship between acquisition of Pseudomonas aeruginosa and previous administration of antibiotics was not confirmed. A more powerful study would perhaps specify this relationship.
Duchamp
Claudine Belpoids
CB
Service d'épidémiologie et d'hygiène hospitalières, Hôpital du Bocage.
Neuwirth
Catherine
C
Milesi-Defrance
Nadine
N
Aho
Ludwig Serge
LS
D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D006259:Craniocerebral Trauma / Q000150:complications; D003428:Cross Infection; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000209:etiology* / Q000473:pathology; D011550:Pseudomonas aeruginosa / Q000472:pathogenicity*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors
D000900:Anti-Bacterial Agents