title: Prevalence and predictors of atopy among young Danish adults.
abstract: BACKGROUND
  The prevalence of atopic diseases is increasing in western countries, and environmental exposures in childhood may influence development of atopic sensitization.
  
  
  OBJECTIVE
  To investigate the prevalence and predictors of atopy among young Danish adults.
  
  
  METHODS
  Of 940 invited subjects, aged 19-29 years, complete data were obtained from 525 (56%) subjects. All completed a questionnaire concerning asthma, rhinitis, preschool nursery care, smoking habits, family size, education and employment. A skin prick test was performed, and pulmonary function was measured using standard techniques. Atopy was defined as a positive skin prick test.
  
  
  RESULTS
  The frequency of atopy was 32% (males 43% vs. females 23%, P < 0.001). We found a positive association between atopy and atopic dermatitis (P < 0.05), rhinitis (P < 0.001), itching when eating nuts (P < 0.001) and current asthma (P < 0.001). There was an inverse relation between atopy and having furred pets in childhood (P < 0.05), passive smoking in childhood (P < 0.01) and current passive smoking (P < 0.05). An increasing number of siblings was inversely related to atopy to grass (P < 0.05); however, only an increasing number of older siblings seemed to protect from atopy to grass (P < 0.05). Subjects who had never attended a day-care centre had significantly more atopy to grass (P < 0.05). No significant association was found between atopy and airway infections requiring hospitalization before the age of 5 years, or between atopy and bedroom sharing in childhood.
  
  
  CONCLUSIONS
  Atopy is common among young Danish adults, especially in males. Participants were less likely to be atopic, especially to grass allergen, if they came from large families, had kept furred pets as children, and had been exposed to tobacco smoke.
authors.affiliation: Department of Internal Medicine, Respiratory Unit, Bispebjerg Hospital, Copenhagen, Denmark. linstow@dadlnet.dk
authors.forename: M-L
authors.initials: ML
authors.lastname: Von Linstow
authors.forename: C
authors.initials: C
authors.lastname: Porsbjerg
authors.forename: C S
authors.initials: CS
authors.lastname: Ulrik
authors.forename: S
authors.initials: S
authors.lastname: Nepper-Christensen
authors.forename: V
authors.initials: V
authors.lastname: Backer
mesh_terms: D000328:Adult; D003718:Denmark / Q000453:epidemiology; D005191:Family Characteristics; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D009790:Occupations; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors