Analysis of human platelet antigen systems in a Moroccan Berber population.
The human platelet alloantigen systems HPA-1, -2, -3, -4, -5 and -6 in a Moroccan Berber population from the Amizmiz region were determined by polymerase chain reaction using sequence-specific primers (PCR-SSP). The gene frequencies obtained from these unrelated Berbers were 0 x 747 and 0 x 252 for HPA-1a and -1b; 0 x 817 and 0 x 182 for HPA-2a and -2b; 0 x 682 and 0 x 317 for HPA-3a and -3b; 1 and 0 x 0 for HPA-4a and -4b; 0 x 8616 and 0 x 1383 for HPA-5a and -5b; 1 and 0 x 0 for HPA-6a and -6b. The Berbers have the highest frequency for the 1b, 2b and 5b alleles of all the populations reported to date and also the lowest frequency for the 3b allele.
Ferrer
G
G
Anthropology Unit, Sciences Faculty, U.A.B.
Muñiz-Diaz
E
E
Aluja
M P
MP
Arilla
M
M
Martinez
C
C
Nogués
R
R
Servin
A
A
Baali
A
A
D016824:Antigens, Human Platelet / Q000145:classification / Q000235:genetics*; D017931:DNA Primers; D005787:Gene Frequency; D006801:Humans; D009018:Morocco / Q000208:ethnology; D016133:Polymerase Chain Reaction / Q000379:methods; D019371:Topography, Medical
D016824:Antigens, Human Platelet; D017931:DNA Primers