[Administration of exogenous surfactant in premature very low birth weight infants with RDS].
A retrospective study is carried out with the aim of establishing the effect from surfactant therapy on pulmonary function, survival and complication from intensive therapy on VLBWI with RDS. 67 premature infants below 1500 grams are included in the study divided in 3 groups: I gr.--27 babies treated with Corosurf; II gr.--16 babies treated with Exosurf; III gr.--24 control babies without surfactant. The results show that in spite of relatively lower gestational age and higher incidence of inborn infection in group I, Curosurf treated babies spend shortest time on mechanical ventilation and oxygen therapy showing lower incidence of BPD, IVH and mortality rate.
Iarŭkova
N
N
Vakrilova
L
L
Slŭncheva
B
B
Dancheva
S
S
Popivanova
A
A
Emilova
Z
Z
Dimitrov
A
A
Chernev
T
T
Nikolov
A
A
D016022:Case-Control Studies; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D010100:Oxygen / Q000627:therapeutic use; D011663:Pulmonary Surfactants / Q000627:therapeutic use*; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D012189:Retrospective Studies; D013997:Time Factors
D011663:Pulmonary Surfactants; D010100:Oxygen