MR temperature measurement in liver tissue at 0.23 T with a steady-state free precession sequence.
MRI can be used for monitoring temperature during a thermocoagulation treatment of tumors. The aim of this study was to demonstrate the suitability of a 3D steady-state free precession sequence (3D Fast Imaging with Steady-State Precession, 3D TrueFISP) for MR temperature measurement at 0.23 T, and to compare it to the spin-echo (SE) and spoiled 3D gradient-echo (3D GRE) sequences. The optimal flip angle for the TrueFISP sequence was calculated for the best temperature sensitivity in the image signal from liver tissue, and verified from the images acquired during the thermocoagulation of excised pig liver. Factors influencing the accuracy of the measured temperatures are discussed. The TrueFISP results are compared to the calculated values of optimized SE and 3D GRE sequences. The accuracy of TrueFISP in the liver at 0.23 T, in imaging conditions used during thermocoagulation procedures, is estimated to be +/-3.3 degrees C for a voxel of 2.5 x 2.5 x 6 mm(3) and acquisition time of 18 s. For the SE and GRE sequences, with similar resolution and somewhat longer imaging time, the uncertainty in the temperature is estimated to be larger by a factor of 2 and 1.2, respectively.
Germain
D
D
Center for Research in Interventional Imaging, Jouy en Josas, France.
Vahala
E
E
Ehnholm
G J
GJ
Vaara
T
T
Ylihautala
M
M
Savart
M
M
Laurent
A
A
Tanttu
J
J
Saint-Jalmes
H
H
D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D004564:Electrocoagulation; D008099:Liver / Q000502:physiology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012680:Sensitivity and Specificity; D013552:Swine