title: [Analysis of MDMA and PCP by GC-MS from patients admitted to the critical care medical center].
abstract: In our country, abuse of methamphetamine has increased. Furthermore, dealings of other drugs by using internet have increased. But, the poison cases of 3,4-methylenedioxymethamphetamine (MDMA) and phencyclidine (PCP) have never been reported in our country. We report an MDMA poison case and a PCP poison case. We could detect MDMA, MDA or PCP by GC-MS from urine and serum of patients admitted to the critical care medical center of Nippon Medical School. Case 1: A 23-year-old foreign female was admitted to our hospital because of disturbance of consciousness. Her friend said that she had been found lying on the floor of the bathroom after taking a tablet. The screening test by Triage showed AMP positive. Not methamphetamine but MDMA and MDA were detected from urine and serum of the patient by GC-MS. Case 2: A 27-year-old foreign female was admitted to our hospital because of restlessness and excitement. Her friend said that she had become restless and excited after taking 15-30 tablets of Tylenol. The screening by Triage showed BZO and PCP positive. Not acetaminophen but PCP was detected in the patient's sample by GC-MS. Drug abuse has expanded to Japan over the border. New responses to abuse drugs with respect to medical treatment and drug analyses should be established.
authors.affiliation: Department of Legal Medicine, Nippon Medical School.
authors.forename: Makoto
authors.initials: M
authors.lastname: Nihira
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Hayakawa
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamada
authors.forename: Makiko
authors.initials: M
authors.lastname: Hayashida
authors.forename: Youkichi
authors.initials: Y
authors.lastname: Ohno
authors.forename: Masato
authors.initials: M
authors.lastname: Miyauchi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D003422:Critical Care; D004636:Emergency Service, Hospital; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007564:Japan; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000097:blood* / Q000506:poisoning*; D010622:Phencyclidine / Q000097:blood* / Q000506:poisoning*; D015813:Substance Abuse Detection / Q000379:methods*
chemical_list: D010622:Phencyclidine; D018817:N-Methyl-3,4-methylenedioxyamphetamine