Quartz crystal analytical sensors: the future of label-free, real-time diagnostics?
Acoustic sensor technologies have a long and prestigious history. However, liquid phase applications based upon thickness shear mode transducers are a relatively recent addition but are nonetheless being rapidly accepted as a broad usage analytical platform upon which to carry out label-free, real-time chemical, biological and pharmaceutical assays. This article discusses the development of thickness shear mode devices, current technologies, with a focus on the breadth of application and the future potential of the technique within the pharmaceutical and biochemical industries.
Pavey
Karl D
KD
School of Pharmacy and Biomolecular Sciences, Cockroft Building, University of Brighton, Moulsecoombe, Brighton, UK. K.D.Pavey@bton.ac.uk
D000162:Acoustics; D001419:Bacteria / Q000302:isolation & purification; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D002477:Cells / Q000166:cytology; D006801:Humans; D007118:Immunoassay / Q000379:methods; D009696:Nucleic Acids / Q000032:analysis / Q000737:chemistry; D011791:Quartz; D012680:Sensitivity and Specificity
D009696:Nucleic Acids; D011791:Quartz