[A case of endobronchial sarcoidosis presenting as a polypoid lesion].
A 51-year-old woman was admitted to our hospital because of deterioration of abnormal chest shadows. Though the shadows had been pointed out at another hospital about two years before, no evaluation had been made at that time. A chest CT scan showed multiple small nodular shadows and thickening of the bronchovascular bundles bilaterally, and marked swollen lymph nodes in the axilla, mediastinum, and bilateral the hili of both lungs. Bronchoscopic evaluation revealed bronchial mucosal hypervascularity and a polypoid lesion at the orifice of the right B8b. The transbronchial biopsy specimen of the polypoid lesion showed non-caseating epithelioid cell granulomas in the bronchial mucosa. The bronchoalveolar lavage revealed a increase in the total number of cells including high levels of lymphocytes. Therefore, a diagnosis of sarcoidosis was made. This is a very rare case of endobronchial sarcoidosis. However, biopsy specimens of normal mucosa in sarcoidosis often show a microscopic sarcoid process, so a diagnosis of endobronchial sarcoidosis in this case should be given prudently.
Ishii
Hiroshi
H
Second Department of Internal Medicine, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, Japan.
Mukae
Hiroshi
H
Matsunaga
Yuko
Y
Kakugawa
Tomoyuki
T
Nagata
Towako
T
Kaida
Hideyuki
H
Sakamoto
Noriho
N
Tsurutani
Hiroko
H
Kadota
Jun-ichi
J
Kohno
Shigeru
S
D001706:Biopsy; D001980:Bronchi / Q000473:pathology*; D001984:Bronchial Neoplasms / Q000473:pathology*; D001999:Bronchoscopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*; D012507:Sarcoidosis / Q000473:pathology*