title: [Desquamative interstitial pneumonia--case report and review of literature].
abstract: A 50-year-old man was admitted to our hospital because diffuse reticulonodular shadows in the bilateral lung fields had deteriorated on chest radiographs during a regular checkup. The bronchoalveolar lavage (BAL) fluid revealed an increase in the total number of cells, including slightly elevated levels of eosinophils and neutrophils. The thoracoscopic lung biopsy specimens showed findings compatible with desquamative interstitial pneumonia (DIP). Corticosteroid therapy was done, and improvement of chest CT findings and pulmonary function were seen. We reviewed the clinical features in seventeen patients with biopsy-proven DIP reported in Japan. All patients have good prognoses and a high frequency of steroid responsiveness. Moreover, many patients were positive for antinuclear antibodies in serological tests, and there was a tendency toward increasing eosinophils in BAL fluids.
authors.affiliation: Second Department of Internal Medicine, Nagasaki University School of Medicine.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishii
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mukae
authors.forename: Yuko
authors.initials: Y
authors.lastname: Matsunaga
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Kakugawa
authors.forename: Towako
authors.initials: T
authors.lastname: Nagata
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kaida
authors.forename: Noriho
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Hiroko
authors.initials: H
authors.lastname: Tsurutani
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kadota
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kohno
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D011379:Prognosis
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone