Nosocomial pneumonia: epidemiology, pathogenesis, diagnosis, treatment and prevention.
Nosocomial pneumonia is the second most common nosocomial infection and the leading cause of death from hospital-acquired infection. Supine body position in mechanically ventilated patients, and cardiopulmonary resuscitation and continuous sedation are significant risk factors for developing nosocomial pneumonia. During the past 2 years some new therapeutic approaches for nosocomial pneumonia and modifications to established therapies have been described, such as optimal pharmacodynamic evaluations, monotherapy versus combination therapy, computer-assisted management programmes and antibiotic rotations.
Lode
Hartmut
H
aDepartment of Chest and Infectious Diseases and bInstitute of Medical Microbiology, Hospital Heckeshorn, affiliated to Freie Universität Berlin, Berlin, Germany.
Raffenberg
Manfred
M
Erbes
Reiner
R
Geerdes-Fenge
Hilte
H
Mauch
Harald
H