Lipase polystyrene giant amphiphiles.
A new type of giant amphiphilic molecule has been synthesized by covalently connecting a lipase enzyme headgroup to a maleimide-functionalized polystyrene tail (40 repeat units). The resulting biohybrid forms catalytic micellar rods in water.
Velonia
Kelly
K
Department of Organic Chemistry, NSR Center, University of Nijmegen, Toernooiveld 1, NL-6525 ED Nijmegen, The Netherlands.
Rowan
Alan E
AE
Nolte
Roeland J M
RJ
D005656:Fungal Proteins; D006863:Hydrogen-Ion Concentration; D008049:Lipase / Q000737:chemistry*; D008958:Models, Molecular; D011137:Polystyrenes / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*
D005656:Fungal Proteins; D011137:Polystyrenes; D013501:Surface-Active Agents; D008049:Lipase; C431349:lipase B, Candida antarctica