title: FIP: a highly automated beamline for multiwavelength anomalous diffraction experiments.
abstract: FIP is a French Collaborating Research Group (CRG) beamline at the European Synchrotron Radiation Facility (ESRF) dedicated exclusively to crystallography of biological macromolecules, with a special emphasis on multiwavelength anomalous diffraction data collection in the 0.7-1.81 A wavelength range. The optics, consisting of long cylindrical grazing-angle mirrors associated with a cryocooled double-crystal monochromator, delivers an optimal beam in the corresponding energy range. The high level of automation, which includes automated crystal centring, automated data-collection management and data processing, makes the use of this beamline very easy. This is illustrated by the large number of challenging structures that have been solved since 1999.
authors.affiliation: Laboratoire de Cristallographie et Cristallogenèse des Protèines (LCCP), Institut de Biologie Structurale J.-P. Ebel CEA-CNRS, 41 Rue Jules Horowitz, 38027 Grenoble CEDEX 1, France.
authors.forename: M
authors.initials: M
authors.lastname: Roth
authors.forename: P
authors.initials: P
authors.lastname: Carpentier
authors.forename: O
authors.initials: O
authors.lastname: Kaïkati
authors.forename: J
authors.initials: J
authors.lastname: Joly
authors.forename: P
authors.initials: P
authors.lastname: Charrault
authors.forename: M
authors.initials: M
authors.lastname: Pirocchi
authors.forename: R
authors.initials: R
authors.lastname: Kahn
authors.forename: E
authors.initials: E
authors.lastname: Fanchon
authors.forename: L
authors.initials: L
authors.lastname: Jacquamet
authors.forename: F
authors.initials: F
authors.lastname: Borel
authors.forename: A
authors.initials: A
authors.lastname: Bertoni
authors.forename: P
authors.initials: P
authors.lastname: Israel-Gouy
authors.forename: J L
authors.initials: JL
authors.lastname: Ferrer
mesh_terms: D001331:Automation / Q000295:instrumentation / Q000379:methods; D002138:Calibration; D003461:Crystallography; D004581:Electronics; D005602:France; D005615:Freezing; D006801:Humans; D009250:NADP Transhydrogenases / Q000737:chemistry; D039502:Nuclear Cap-Binding Protein Complex / Q000737:chemistry; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D016187:Receptors, Granulocyte-Macrophage Colony-Stimulating Factor / Q000737:chemistry; D018123:Receptors, Interleukin / Q000737:chemistry; D012984:Software; D013050:Spectrometry, Fluorescence; D017356:Synchrotrons / Q000295:instrumentation*; D013696:Temperature; D014961:X-Ray Diffraction / Q000295:instrumentation* / Q000379:methods*
chemical_list: D039502:Nuclear Cap-Binding Protein Complex; D011506:Proteins; D016187:Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; D018123:Receptors, Interleukin; D009250:NADP Transhydrogenases