Helicobacter and gastric MALT lymphoma.
Helicobacter pylori infection is a pre-MALT lymphoma condition. H pylori eradication leads to complete remission in 80% of low grade stage E1 lymphomas, with a yearly recurrence rate of approximately 5%. The possibility for complete remission in high grade lymphomas needs to be investigated in prospective studies. In addition, the significance of persistent B cell monoclonality (stable disease? danger of relapse? regression of monoclonality?) needs to be investigated in follow up studies.
Stolte
M
M
Institut für Pathologie, Klinikum Bayreuth, 95445 Bayreuth, Germany. pathologie.klinikum@bnbt.de
Bayerdörffer
E
E
Morgner
A
A
Alpen
B
B
Wündisch
T
T
Thiede
C
C
Neubauer
A
A
D000818:Animals; D001706:Biopsy; D018450:Disease Progression; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D005756:Gastritis / Q000188:drug therapy / Q000382:microbiology*; D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology