title: An infected hip prosthesis in a dog diagnosed with a 99mTc-ciprofloxacin (infecton) scan.
abstract: This case report describes the use of the 99mTc-labeled radiopharmaceutical ciprofloxacin (Infecton) in a case of hip prosthesis loosening in a dog. Serial planar radiographs were not conclusive, and culture of the synovial fluid was negative. Antibiotic treatment did not result in improvement of the lameness. Scintigraphy was performed with 99-Tc-Infecton, a tracer claimed to be specific for infection. Antibiotic treatment was interrupted 6 weeks prior to the examination. Planar and tomographic images at 3 h and at 24 h postinjection showed increased activity along the acetabulum and the proximal femoral bone surrounding the femoral prosthesis, indicating focal infection. Bacteriology performed after removal of the implant revealed Pseudomonas aeruginosa.
authors.affiliation: Department of Medical Imaging, Faculty of Veterinary Medicine, University Ghent, Merelbeke, Belgium.
authors.forename: K
authors.initials: K
authors.lastname: Peremans
authors.forename: F
authors.initials: F
authors.lastname: De Winter
authors.forename: L
authors.initials: L
authors.lastname: Janssens
authors.forename: F
authors.initials: F
authors.lastname: Dumont
authors.forename: H
authors.initials: H
authors.lastname: Van Bree
authors.forename: R
authors.initials: R
authors.lastname: Dierckx
mesh_terms: D000818:Animals; D002939:Ciprofloxacin / Q000031:analogs & derivatives*; D004283:Dog Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D005260:Female; D006622:Hip Prosthesis / Q000662:veterinary*; D015609:Organotechnetium Compounds; D011475:Prosthesis Failure / Q000662:veterinary*; D011552:Pseudomonas Infections / Q000000981:diagnostic imaging / Q000662:veterinary*; D011877:Radionuclide Imaging
chemical_list: D015609:Organotechnetium Compounds; C431804:Technetium Tc 99m ciprofloxacin; D002939:Ciprofloxacin