Cataract surgery in allogeneic bone marrow transplant recipients with graft-versus-host disease(1).
OBJECTIVE
To study the outcomes of cataract surgery in allogeneic bone marrow transplant recipients with documented graft-versus-host disease (GVHD) and to elucidate the concomitant ocular surface problems often encountered in these patients.


METHODS
W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.


METHODS
This retrospective study comprised 12 cataract surgeries in 7 patients with GVHD) after allogeneic bone marrow transplantation. In particular, visual acuity improvement, surgical complications, and problems associated with concomitant ocular surface disease were reviewed.


RESULTS
The mean visual acuity improved significantly from 20/46 (logMAR 0.32) preoperatively to 20/21 (logMAR 0.02) postoperatively (P <.005). The mean postoperative follow-up was 23 months (range 3 to 48 months). All patients had dry eyes, and 3 had conjunctival cicatrization with mild keratinization. No patient had postoperative corneal breakdown.


CONCLUSIONS
With aggressive management of dry eyes and other ocular surface problems, cataract surgery had excellent outcomes in patients with GVHD.
Penn
Esther A
EA
W.K. Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, Michigan 48105, USA.
Soong
H Kaz
HK
D000328:Adult; D001082:Aqueous Humor / Q000378:metabolism; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002386:Cataract / Q000209:etiology*; D015352:Dry Eye Syndromes / Q000209:etiology / Q000378:metabolism; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011183:Postoperative Complications; D012189:Retrospective Studies; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D014792:Visual Acuity