[Scleredema adultorum in secondary hyperparathyroidism].
Scleredema adultorum, or Buschke's scleredema, belongs to the group of mucinoses. It is characterised by thickened and indurated skin. Histopathology shows thickened dermis with an infiltration of mucin between swollen collagen bundles. There are reports about many associations with scleredema adultorum, e.g., with diabetes mellitus and multiple myeloma. One case is known with associated primary hyperparathyroidism. For the first time we report a case of scleredema adultorum and secondary hyperparathyroidism, in a 46-year-old patient. Both forms of hyperparathyroidism have increased levels of parathormone. Therefore, these increased levels could have an influence on collagen metabolism.
Jacob
N
N
Hautklinik am Klinikum Minden, Portastrasse 7-9, 32423 Minden.
Gleichmann
U
U
Stadler
R
R
D001706:Biopsy; D003094:Collagen / Q000378:metabolism; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism; D012592:Scleredema Adultorum / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D012867:Skin / Q000473:pathology
D009077:Mucins; D003094:Collagen