title: [Association of atypical pulmonary TB, polyserositis, severe leukopenia and panniculitis. Case report].
abstract: Many reports have associated tuberculosis with haematological abnormalities. These reports suggest that severe pulmonary tuberculosis, if associated with reduced tissue cellular reaction, may cause blood discrasias. Anemia was present in 32 percent of patients. Leucopenia with neutropenia and lymphopenia was observed in 15 percent in patients with very severe clinical tuberculosis. Active tuberculosis was associated with significant reductions in absolute numbers of total T, T4 and B lymphocytes, but there were no significant differences in total T8 counts. T4 lymphopenia causes reversal of T4/T8 ratio. Also, many histopathologic diagnosis of panniculitis have been reported in tuberculosis patients--the incidence of panniculitis caused by tuberculosis was 8.2%. We present a case of secondary pulmonary tuberculosis with atypically Rx changes, associated with polyserositis and severe leucopenia, which debuted with a panniculitis.
authors.affiliation: Serviciul de hematologie, Spitalul Colţea.
authors.forename: F
authors.initials: F
authors.lastname: Mihălţan
authors.forename: A
authors.initials: A
authors.lastname: Lupu
authors.forename: D
authors.initials: D
authors.lastname: Ungureanu
authors.forename: G
authors.initials: G
authors.lastname: Halic
authors.forename: C
authors.initials: C
authors.lastname: Badea
authors.forename: C
authors.initials: C
authors.lastname: Marcu
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D007866:Leg; D007970:Leukopenia / Q000209:etiology; D008231:Lymphopenia / Q000097:blood / Q000209:etiology*; D015434:Panniculitis / Q000188:drug therapy / Q000209:etiology*; D010493:Pericarditis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D011241:Prednisone / Q000627:therapeutic use; D011859:Radiography; D014396:Tuberculosis, Pleural / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents; D007538:Isoniazid; D011241:Prednisone