title: Design of near-infrared imaging probe with the assistance of ultrasound localization.
abstract: A total of 364 optical source-detector pairs were deployed uniformly over a 9 cm x 9 cm probe area initially, and then the total pairs were reduced gradually to 60 in experimental and simulation studies. For each source-detector configuration, three-dimensional (3-D) images of a 1-cm-diameter absorber of different contrasts were reconstructed from the measurements made with a frequency-domain system. The results have shown that more than 160 source-detector pairs are needed to reconstruct the absorption coefficient to within 60% of the true value and appropriate spatial and contrast resolution. However, the error in target depth estimated from 3-D images was more than 1 cm in all source-detector configurations. With the a priori target depth information provided by ultrasound, the accuracy of the reconstructed absorption coefficient was improved by 15% and 30% on average, and the beam width was improved by 24% and 41% on average for high- and low-contrast cases, respectively. The speed of reconstruction was improved by ten times on average.
authors.affiliation: Department of Electrical and Computer Engineering, University of Connecticut, Storrs 06269, USA. zhu@engr.uconn.edu
authors.forename: Q
authors.initials: Q
authors.lastname: Zhu
authors.forename: N G
authors.initials: NG
authors.lastname: Chen
authors.forename: D
authors.initials: D
authors.lastname: Piao
authors.forename: P
authors.initials: P
authors.lastname: Guo
authors.forename: X
authors.initials: X
authors.lastname: Ding