title: Continuous epidural infusion of 0.05% bupivacaine plus hydromorphone for labor analgesia: an observational assessment in 1830 parturients.
abstract: We evaluated a continuous epidural infusion containing bupivacaine 0.05% plus the opioid hydromorphone in 1830 women requesting pain relief during labor and delivery. The infusion provided effective analgesia with minimal adverse events for patients differing in parity and at varying stages of labor. Pain relief was maintained in most patients without the need for epidural reinforcement with more concentrated doses of local anesthetic.
authors.affiliation: Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut 06520-8051, USA.
authors.forename: Raymond S
authors.initials: RS
authors.lastname: Sinatra
authors.forename: Steven
authors.initials: S
authors.lastname: Eige
authors.forename: James H
authors.initials: JH
authors.lastname: Chung
authors.forename: K Sam
authors.initials: KS
authors.lastname: Chung
authors.forename: Ferne B
authors.initials: FB
authors.lastname: Sevarino
authors.forename: Ana
authors.initials: A
authors.lastname: Lobo
authors.forename: Lee
authors.initials: L
authors.lastname: Fermo
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Ocampo
mesh_terms: D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D004091:Hydromorphone / Q000008:administration & dosage*; D011247:Pregnancy; D011446:Prospective Studies
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D004091:Hydromorphone; D002045:Bupivacaine