title: Complications associated with bone cementing for the treatment of giant cell tumors of bone.
abstract: Aretrospective review was conducted of giant cell tumors treated between 1984 and 1998 using the technique of aggressive curettage through a large bone window followed by acrylic cement reconstruction. Fifteen patients with a mean follow-up time of 46 months (range, 24-188 months) were identified. One patient had a local recurrence 24 months postoperatively. All the patients showed a radiolucent zone at the bone-cement interface up to 2.5 mm in width during the first 6 months after operation. However, the radiolucent zones were nonprogressive and did not affect the stability of the bone cement. Osteoarthritis of the knee joint occurred 14 years postoperatively in one patient with an intraarticular fracture at presentation. A stress fracture occurred in one patient who had the largest tumor in the distal femur. Acrylic cement reconstruction is a safe and effective procedure that provides local adjuvant therapy. Giant cell tumors with an associated intraarticular fracture remain a challenging problem to treat.
authors.affiliation: Department of Orthopaedic Surgery, Sapporo Medical University, South-1, West-16, Sapporo 060-8543, Japan.
authors.forename: Takuro
authors.initials: T
authors.lastname: Wada
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Kaya
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nagoya
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kawaguchi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Isu
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Yamashita
authors.forename: Shinya
authors.initials: S
authors.lastname: Yamawaki
authors.forename: Seiichi
authors.initials: S
authors.lastname: Ishii
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001843:Bone Cements / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D019904:Polymethyl Methacrylate / Q000009:adverse effects* / Q000627:therapeutic use; D011183:Postoperative Complications / Q000209:etiology*; D011859:Radiography; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate