Ocular involvement in Takayasu's arteritis: response to cyclophosphamide therapy.
OBJECTIVE
To report a Takayasu's arteritis (TA) case with an intense ocular involvement and the response to monthly bolus of Cyclophosphamide.


METHODS
Case report and literature review.


RESULTS
Cyclophosphamide was useful to improve the TA symptoms without any additional treatment and any secondary effects. When this therapy was discontinued the ocular symptoms progressed.


CONCLUSIONS
Although no definitive therapy has been established, Cyclophosphamide intravenous bolus may be useful to improve ocular symptoms of Takayasu's Arteritis, specially in early stages. There are not adequate descriptions in the literature concerning the effect of this treatment on the ocular manifestations of TA.
Rodríguez-Hurtado
Francisco J
FJ
Service of Ophthalmology, Virgen de las Nieves, University Hospital, Granada, Spain. frodriguezhu@nexo.es
Sabio
J M
JM
Lucena
J
J
Jiménez-Alonso
J
J
D000328:Adult; D000792:Angiography; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use*; D005128:Eye Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D006801:Humans; D013625:Takayasu Arteritis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*
D003520:Cyclophosphamide