title: Evolution of the membrane guanylate cyclase transduction system.
abstract: Almost four decades of research in the field of membrane guanylate cyclases is discussed in this review. Primarily, it focuses on the chronological development of the field, recognizes major contributions of the original investigators, corrects certain misplaced facts, and projects its future trend.
authors.affiliation: Departments of Cell Biology, SOM and NJMS, University of Medicine and Dentistry of New Jersey, Stratford 08084, USA. sharmark@umdnj.edu
authors.forename: Rameshwar K
authors.initials: RK
authors.lastname: Sharma
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000201:enzymology*; D019143:Evolution, Molecular; D006162:Guanylate Cyclase / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008958:Models, Molecular; D011487:Protein Conformation; D017382:Reactive Oxygen Species / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D017382:Reactive Oxygen Species; D011956:Receptors, Cell Surface; D000255:Adenosine Triphosphate; D006162:Guanylate Cyclase; D002118:Calcium