Scanning electron microscopic description of cellular activity and mineral changes in feline odontoclastic resorptive lesions.
The cellular activity and changes in mineral composition of dental tissues involved in feline odontoclastic resorptive lesions were investigated. Teeth with at least 1 lesion (n = 10) were extracted from 10 different cats that were presented primarily for chronic gingivostomatitis and/or severe periodontal disease. Scanning electron microscopic methods were used to determine the presence of resorptive cells in 8 teeth while 2 teeth were evaluated for pathologic changes in dental mineral composition. Observations were complicated by the presence of organic wear on the dental surfaces, however resorptive cells could be clearly identified in feline odontoclastic resorptive lesions. Resorptive cells had morphologic features indicative of "osteoclast-like" cells or odontoclasts. Resorptive cell activity created a resorption area of darker dentin continuous with physiologic dentin. The darker dentin area seemed poorly mineralized and showed a significantly lower calcium/phosphorous ratio compared with adjacent physiologic denting in 1 tooth. A significantly higher level of magnesium combined with available carbonate ions may have increased the solubility in areas of darker dentin.
Gauthier
O
O
Department of Surgery, National Veterinary School of Nantes, Atlanpole-La Chantrerie, BP 40706, 44307, Nantes, France.
Boudigues
S
S
Pilet
P
P
Aguado
E
E
Heymann
D
D
Daculsi
G
G
D000818:Animals; D002118:Calcium; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D003804:Dentin / Q000737:chemistry* / Q000648:ultrastructure*; D005882:Gingival Diseases / Q000473:pathology / Q000662:veterinary; D008855:Microscopy, Electron, Scanning / Q000662:veterinary; D008903:Minerals / Q000737:chemistry; D010010:Osteoclasts / Q000648:ultrastructure; D010758:Phosphorus; D014081:Tooth Extraction / Q000662:veterinary; D014091:Tooth Resorption / Q000473:pathology / Q000662:veterinary*
D008903:Minerals; D010758:Phosphorus; D002118:Calcium