Andes virus and first case report of Bermejo virus causing fatal pulmonary syndrome.
Two suspected hantavirus pulmonary syndrome (HPS) cases from Bolivia occurred in May and July 2000 and were confirmed by enzyme-linked immunosorbent assay (ELISA)-ANDES using N-Andes recombinant antigen serology. Clot RNAs from the two patients were subjected to reverse transcription-polymerase chain reaction (PCR) amplification and sequencing. We describe two characterized cases of HPS. One was caused by infection with Bermejo virus and the other with Andes Nort viral lineage, both previously obtained from Oligoryzomys species. This is the first report of molecular identification of a human hantavirus associated with Bermejo virus.
Padula
Paula
P
Instituto Nacional de Enfermedades Infecciosas, Buenos Aires, Argentina. ppadula@cvtci.com.ar
Della Valle
Marcelo González
MG
Alai
María Garcia
MG
Cortada
Pedro
P
Villagra
Mario
M
Gianella
Alberto
A
D000328:Adult; D001838:Bolivia; D017809:Fatal Outcome; D006476:Orthohantavirus / Q000235:genetics / Q000302:isolation & purification*; D018804:Hantavirus Pulmonary Syndrome / Q000175:diagnosis / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D017422:Sequence Analysis, DNA