[Confined placental mosaicism: definition, consequences and outcome].
Confined placental mosaicism (CPM) occurs in approximately 2 per cent of viable pregnancies studies by chorionic villus sampling. The great majority of pregnancies with confined placental mosaicism proceed uneventfully, resulting in normal liveborn infants. However, a few specific chromosomal abnormalities have been associated with fetal growth retardation. Fetal karyotype should be checked by amniocentesis and such pregnancies should have careful ultrasound follow-up.
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Service de Gynécologie-Obstétrique (Pr Cabrol), Maternité Port-Royal, 123, boulevard de Port-Royal, 75014 Paris.
D000649:Amniocentesis; D001706:Biopsy; D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations; D005260:Female; D005317:Fetal Growth Retardation / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D010920:Placenta; D011247:Pregnancy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis; D014327:Trophoblasts; D024182:Uniparental Disomy