title: CAP1 expression is developmentally regulated in Xenopus.
abstract: We have cloned and characterized a Xenopus member of the cyclase associated protein (CAP) gene family. xCAP1 is expressed as a maternal transcript, but is up-regulated prior to gastrulation and subsequently localizes to head mesenchyme, lens, otic vesicle, and trunk mesoderm including the pronephros. At different stages, the gene also appears to differentiate surface from deep (sensorial) ectoderm. As in Drosophila, Xenopus CAP1 is expressed in the developing eye, specifically in the differentiating lens. However, in distinction to Drosophila, Xenopus CAP1 does not express in periodically arrayed neural bands.
authors.affiliation: Department of Biological Sciences, University of Windsor, 401 Sunset, Windsor, Ontario, Canada, N9B 3P4.
authors.forename: F
authors.initials: F
authors.lastname: KhosrowShahian
authors.forename: A V
authors.initials: AV
authors.lastname: Hubberstey
authors.forename: M J
authors.initials: MJ
authors.lastname: Crawford
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000096:biosynthesis* / Q000235:genetics; D003001:Cloning, Molecular; D003598:Cytoskeletal Proteins; D029721:Drosophila Proteins; D005123:Eye / Q000196:embryology; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D008840:Microfilament Proteins; D012333:RNA, Messenger / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012697:Serine Endopeptidases; D013997:Time Factors; D015854:Up-Regulation; D014981:Xenopus; D029867:Xenopus Proteins
chemical_list: C410502:Capt protein, Drosophila; D018797:Cell Cycle Proteins; D003598:Cytoskeletal Proteins; D029721:Drosophila Proteins; D008840:Microfilament Proteins; D012333:RNA, Messenger; D029867:Xenopus Proteins; C108632:Cap1 protein, Xenopus; D012697:Serine Endopeptidases