title: On the diagnosis of polycythaemia vera as assessed in the health and medical care in the Västra Götaland region, Sweden.
abstract: OBJECTIVE
  The aim was to assess how the diagnosis of polycythaemia vera (PV) was established and to study to which extent the classic Polycythemia Vera Study Group (PVSG) criteria and the revised criteria for the diagnosis of PV as proposed by Pearson and Messinezy in 1996 (PM criteria) were fulfilled when the diagnosis of PV was made.
  
  
  METHODS
  A questionnaire was sent to physicians in charge of haematological patients at the departments of medicine in 12 hospitals in the Health and Medical Care in the Västra Götaland Region (VGR), Sweden, with a population of 1.5 million inhabitants; they were asked to provide reports as regards all patients with an unequivocal diagnosis of PV during a 5-year period from January 1994 to December 1998.
  
  
  METHODS
  Full reports were obtained from six hospitals, which serve about 1.1 million inhabitants. The results from a total of 129 PV patients, 62 from two university hospitals (UHs) and 67 from four county hospitals (CHs), were the subject of the present analysis. Results. It was shown that measurement of the red cell mass (RCM) had been carried out in 61 of 62 (98%) patients in UHs compared with 24 of 67 (36%) patients at CHs (P < 0.01). By using ultrasound imaging and/or scintigraphy the spleen size had been determined in 55 of 62 (89%) patients at UHs and in 24 of 67 (36%) patients at CHs (P < 0.01). At the UHs, arterial oxygen saturation had been measured in 32 of 62 (52%) patients; the corresponding figure for the CH patients was 22 of 67 (33%). Plasma or serum erythropoietin (EPO) concentrations had been measured in 44 of 62 (71%) of PV patients at UHs and in 31 of 67 (46%) of patients at CHs; in all these cases the EPO concentrations were subnormal or not measurable.
  
  
  CONCLUSIONS
  At the UHs only 37% of the PV patients fulfilled the PVSG criteria for the diagnosis of PV whereas the corresponding figure for CHs was 4% (P < 0.01). The adherence to PM criteria was, however, 71% at UHs compared with 16% at CHs (P < 0.01).
authors.affiliation: Haematology Section, Department of medicine, Sahlgrenska University hospital, Göteborg, Sweden. peter.l.johansson@vgregion.se
authors.forename: P
authors.initials: P
authors.lastname: Johansson
authors.forename: B
authors.initials: B
authors.lastname: Andréasson
authors.forename: S
authors.initials: S
authors.lastname: Safai-Kutti
authors.forename: C
authors.initials: C
authors.lastname: Rhedin
authors.forename: L
authors.initials: L
authors.lastname: Vilén
authors.forename: J
authors.initials: J
authors.lastname: Väärt
authors.forename: J
authors.initials: J
authors.lastname: Kutti
mesh_terms: D000328:Adult; D004911:Erythrocyte Volume; D004921:Erythropoietin / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D011087:Polycythemia Vera / Q000175:diagnosis*; D011795:Surveys and Questionnaires; D013548:Sweden
chemical_list: D004921:Erythropoietin