title: Activities of new fluoroquinolones, ketolides, and other antimicrobials against blood culture isolates of viridans group streptococci from across Canada, 2000.
abstract: The rates of nonsusceptibility to penicillin, erythromycin, and clindamycin of 191 blood culture isolates of viridans group streptococci collected from across Canada in 2000 were 36, 42, and 10%, respectively. Although 8% of the strains were resistant to ciprofloxacin (MIC >or= 4 microg/ml), the MICs of gemifloxacin, BMS 284756, telithromycin, and ABT 773 at which 90% of the strains were inhibited were 0.06, 0.06, 0.12, and 0.03 microg/ml, respectively.
authors.affiliation: University of Toronto, Toronto, Canada.
authors.forename: Andrea S
authors.initials: AS
authors.lastname: Gershon
authors.forename: Joyce C S
authors.initials: JC
authors.lastname: de Azavedo
authors.forename: Allison
authors.initials: A
authors.lastname: McGeer
authors.forename: Krystyna I
authors.initials: KI
authors.lastname: Ostrowska
authors.forename: Deirdre
authors.initials: D
authors.lastname: Church
authors.forename: Daryl J
authors.initials: DJ
authors.lastname: Hoban
authors.forename: Godfrey K M
authors.initials: GK
authors.lastname: Harding
authors.forename: Karl
authors.initials: K
authors.lastname: Weiss
authors.forename: Lewis
authors.initials: L
authors.lastname: Abbott
authors.forename: Fiona
authors.initials: F
authors.lastname: Smaill
authors.forename: Marie
authors.initials: M
authors.lastname: Gourdeau
authors.forename: Gilles
authors.initials: G
authors.lastname: Murray
authors.forename: Donald E
authors.initials: DE
authors.lastname: Low
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology; D001769:Blood / Q000382:microbiology*; D002170:Canada; D003470:Culture Media; D024881:Drug Resistance, Bacterial; D024841:Fluoroquinolones; D006801:Humans; D018942:Macrolides; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards; D013290:Streptococcal Infections / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D003470:Culture Media; D024841:Fluoroquinolones; D018942:Macrolides