title: Diagnostic value of history and physical examination in patients suspected of lumbosacral nerve root compression.
abstract: OBJECTIVE
  To evaluate patient characteristics, symptoms, and examination findings in the clinical diagnosis of lumbosacral nerve root compression causing sciatica.
  
  
  METHODS
  The study involved 274 patients with pain radiating into the leg. All had a standardised clinical assessment and magnetic resonance (MR) imaging. The associations between patient characteristics, clinical findings, and lumbosacral nerve root compression on MR imaging were analysed.
  
  
  RESULTS
  Nerve root compression was associated with three patient characteristics, three symptoms, and four physical examination findings (paresis, absence of tendon reflexes, a positive straight leg raising test, and increased finger-floor distance). Multivariate analysis, analysing the independent diagnostic value of the tests, showed that nerve root compression was predicted by two patient characteristics, four symptoms, and two signs (increased finger-floor distance and paresis). The straight leg raise test was not predictive. The area under the curve of the receiver-operating characteristic was 0.80 for the history items. It increased to 0.83 when the physical examination items were added.
  
  
  CONCLUSIONS
  Various clinical findings were found to be associated with nerve root compression on MR imaging. While this set of findings agrees well with those commonly used in daily practice, the tests tended to have lower sensitivity and specificity than previously reported. Stepwise multivariate analysis showed that most of the diagnostic information revealed by physical examination findings had already been revealed by the history items.
authors.affiliation: Department of Neurology, Maastricht University Hospital, Maastricht, The Netherlands. pvr@sneu.azm.nl
authors.forename: P C A J
authors.initials: PC
authors.lastname: Vroomen
authors.forename: M C T F M
authors.initials: MC
authors.lastname: de Krom
authors.forename: J T
authors.initials: JT
authors.lastname: Wilmink
authors.forename: A D M
authors.initials: AD
authors.lastname: Kester
authors.forename: J A
authors.initials: JA
authors.lastname: Knottnerus
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D009460:Neurologic Examination; D010808:Physical Examination; D011237:Predictive Value of Tests; D011843:Radiculopathy / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D012585:Sciatica / Q000209:etiology*; D012680:Sensitivity and Specificity