Benign lymphoid infiltrate of the iris simulating a malignant melanoma.
OBJECTIVE
To report a clinicopathologic correlation of an unusual benign lymphocytic iris mass in a patient who had no systemic lymphoproliferative disease.


METHODS
Case report.


RESULTS
A 49-year-old man developed a circumscribed, tan lesion in his left iris. The lesion was suspected clinically to be an atypical iris melanoma. Histopathologic studies of the resected mass revealed a solid tumor that was comprised of lymphocytes and histiocytes. Immunohistochemical studies identified that most of the cells were T lymphocytes. The histopathologic diagnosis was atypical lymphoid infiltrate. Workup for systemic lymphoma and Epstein-Barr virus infection was negative.


CONCLUSIONS
Lymphoid infiltrate can manifest as a solitary mass that can simulate an iris melanoma.
Sharma
Mithlesh C
MC
Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Shields
Carol L
CL
Shields
Jerry A
JA
Eagle
Ralph C
RC
Demirci
Hakan
H
Wiley
Lee
L
D003937:Diagnosis, Differential; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D015811:Iris Neoplasms / Q000175:diagnosis*; D008223:Lymphoma / Q000175:diagnosis*; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D008875:Middle Aged; D013601:T-Lymphocytes / Q000473:pathology