[Acetylcholine receptor antibodies in patients with myasthenia].
Acethylcholine receptor (AChR) antibodies in patients with myasthenia were studied for the first time in Russia with radioimmuno-assay application. Seronegative result (antibody titer lower than 0.2 nmol/l) was obtained for 33% of the patients and seropositive one (antibody titer higher than 0.2 nmol/l)--for 67%. AChR antibodies level varied from 1.9 to 115.0 nmol/l. The AChR antibodies were found more frequently and in higher titers in women than in men. Correlation analysis revealed strong correlation between AChR antibodies level and severity of myasthenia.
Neretin
V Ia
VIa
Kotov
S V
SV
Gekht
B M
BM
Agafonov
B V
BV
Lokhmiuller
G
G
Sidorova
O P
OP
Sepp
E K
EK
Shcherbakova
N I
NI
Kalinenkova
S G
SG
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000453:epidemiology / Q000276:immunology* / Q000601:surgery; D011182:Postoperative Care; D011300:Preoperative Care; D011950:Receptors, Cholinergic / Q000276:immunology*; D012720:Severity of Illness Index; D013934:Thymectomy
D000906:Antibodies; D011950:Receptors, Cholinergic