title: Post-operative paraplegia following spinal cord infarction.
abstract: Thoracic epidural analgesia is a frequently utilised technique. Neurological complications are uncommon, but of grave consequence with significant morbidity. Spinal cord infarction following epidural anaesthesia is rare. We present a case where a hypertensive patient underwent an elective sigmoid colectomy under combined general/epidural anaesthesia for a suspected malignant abdominal mass. An epidural infusion was used for intra-operative and post-operative analgesia. During surgery, the blood pressure was labile and she was hypotensive. Postoperatively, the patient became confused, pyrexial and tachycardic and developed systemic inflammatory response syndrome requiring intensive care management. She developed a flaccid paralysis at L3 level with areflexia, analgesia and impaired sensation. A spinal cord infarct in the region of the conus extending into the thoracic cord was diagnosed. Complications of epidural anaesthesia are easily recognised when they develop immediately; their relationship to the anaesthesia and the post-operative period may be misjudged or underestimated when they appear after a delay, if neurological signs are masked by lack of patient cooperation and drowsiness or if the epidural anaesthesia is prolonged by long-acting drugs. New neurological deficits should be evaluated promptly to document the evolving neurological status and further testing or intervention should be arranged if appropriate. The association with epidural anaesthesia as a cause of paraplegia is reviewed. The aetiological factors that may have contributed to this tragic neurological complication are discussed.
authors.affiliation: Department of Anaesthesia, Royal Cornwall Hospital, Truro, Cornwall, England.
authors.forename: L
authors.initials: L
authors.lastname: Weinberg
authors.forename: W R
authors.initials: WR
authors.lastname: Harvey
authors.forename: R J
authors.initials: RJ
authors.lastname: Marshall
mesh_terms: D000767:Anesthesia, Epidural / Q000009:adverse effects*; D003082:Colectomy; D005260:Female; D006801:Humans; D007238:Infarction / Q000150:complications* / Q000209:etiology; D008875:Middle Aged; D010264:Paraplegia / Q000209:etiology*; D011183:Postoperative Complications / Q000209:etiology*; D013119:Spinal Cord Injuries / Q000150:complications* / Q000209:etiology