title: Origin and minimization of residual motion-related artifacts in navigator-corrected segmented diffusion-weighted EPI of the human brain.
abstract: Motion sensitivity in diffusion-weighted imaging (DWI) can be effectively suppressed using single-shot echo-planar imaging (EPI). However, segmented (multishot) EPI is often used to increase resolution and reduce spatial distortions, which in turn increases susceptibility to brain motion. The sources of these residual motion artifacts in navigator-echo-corrected segmented EPI images of the brain were investigated. The results indicate that the dominant source of these artifacts is cardiac pulsation with occasional involuntary movement of the subject. The relationship between the cardiac cycle and motion artifacts shows that optimum timing for the data acquisition is possible. In addition it is shown that the effects of involuntary motion can be removed by swapping k-space data between redundant datasets.
authors.affiliation: Department of Radiology, Division of MRI Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
authors.forename: Hangyi
authors.initials: H
authors.lastname: Jiang
authors.forename: Xavier
authors.initials: X
authors.lastname: Golay
authors.forename: Peter C M
authors.initials: PC
authors.lastname: van Zijl
authors.forename: Susumu
authors.initials: S
authors.lastname: Mori
mesh_terms: D016477:Artifacts; D001783:Blood Flow Velocity; D001921:Brain / Q000033:anatomy & histology*; D017536:Carotid Artery, Common / Q000033:anatomy & histology; D017352:Echo-Planar Imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009038:Motion