title: [Fernand Widal syndrome: apropos of 2 cases].
abstract: The Fernand Widal syndrome combines a nasal polyposis, an asthma and aspirin sensitivity. It remains a nosological entity often unrecognized because of the trivialization of aspirin in-take on the one hand the other its etiopathogenesis which has not yet been clarified because of the inhibition of the cyclo-oxygenase. In actual fact the aspirin molecule has yet to reveal all its secrets (advantages and disadvantages). We report 2 cases of Fernand Widal syndrome observed in 2 women in their thirties with a notion of atopy in one at the Pneumophtisiology clinic at the Fann University Hospital in Dakar. The confirmed diagnosis was based on oral provocative test in addition to suggestive clinical signs which emphasize the classical triad with a chronological appearance more or less typical. The best treatment could combine inhaled corticotherapy, nasalization of sinus cavities, antihistaminics, no aspirin in take and educating the patient.
authors.affiliation: Service de Pneumophtisiologie C.H.U. de FANN BP: 5035 Dakar/Fann.
authors.forename: M
authors.initials: M
authors.lastname: Ndiaye
authors.forename: A A
authors.initials: AA
authors.lastname: Hane
authors.forename: M
authors.initials: M
authors.lastname: Ndir
authors.forename: O
authors.initials: O
authors.lastname: Ba
authors.forename: S
authors.initials: S
authors.lastname: Cissokho
authors.forename: M
authors.initials: M
authors.lastname: Kandji
authors.forename: S
authors.initials: S
authors.lastname: Ndiaye
authors.forename: A
authors.initials: A
authors.lastname: Diatta
authors.forename: A
authors.initials: A
authors.lastname: Niang
authors.forename: Y
authors.initials: Y
authors.lastname: Dia
authors.forename: R
authors.initials: R
authors.lastname: Diouf
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000209:etiology; D001241:Aspirin / Q000009:adverse effects* / Q000494:pharmacology; D001249:Asthma / Q000139:chemically induced* / Q000209:etiology; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects*; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000150:complications*; D015523:Maxillary Sinusitis / Q000150:complications; D009298:Nasal Polyps / Q000209:etiology*; D012221:Rhinitis, Allergic, Perennial / Q000150:complications; D007319:Sleep Initiation and Maintenance Disorders / Q000150:complications; D013577:Syndrome
chemical_list: D016861:Cyclooxygenase Inhibitors; D001241:Aspirin