title: The influence of cisplatinum and goserelinum on the magnesium and calcium level in rat serum.
abstract: The influence of cisplatinum and goserelinum on the magnesium and calcium concentration in rat serum has been studied. The cisplatinum induces decrease in serum magnesium concentration (to 70%), and calcium concentration (to 63%). Goserelinum activity was similar to cisplatinum activity. The magnesium concentration decreased to 60%, and calcium to 44%. In condition of cisplatinum and goserelinum activity the hypomagnesemia and hypocalcemia were noted.
authors.affiliation: Department of Human Physiology, Medical University of Lublin.
authors.forename: L
authors.initials: L
authors.lastname: Klukowska
authors.forename: A
authors.initials: A
authors.lastname: Nadulska
authors.forename: S
authors.initials: S
authors.lastname: Dyba
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D002118:Calcium / Q000097:blood*; D002945:Cisplatin / Q000494:pharmacology*; D017273:Goserelin / Q000494:pharmacology*; D006996:Hypocalcemia / Q000139:chemically induced; D008274:Magnesium / Q000097:blood*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000970:Antineoplastic Agents; D017273:Goserelin; D008274:Magnesium; D002945:Cisplatin; D002118:Calcium