Electrophysiological correlates of visual categorization: evidence for cognitive dysfunctions in early Parkinson's disease.
Our aim was to examine the electrophysiological correlates of perceptual categorization in Parkinson's disease (PD). We recorded visual event-related potentials (ERPs) in a natural scene categorization task in drug naive idiopathic PD patients and healthy control subjects. In the control group, there was a significant early difference (150-250 ms poststimulus) between ERPs elicited by pictures containing animals and scenes without animals. In spite of relatively preserved basic-level visual functions, this was not observable in the PD group. These results raise the possibility for striatal contributions to visual categorization and may provide a novel protocol for further clinical studies.
Antal
Andrea
A
Department of Physiology, University of Szeged, Faculty of Medicine, Szeged, Hungary. aantal@gwdg.de
Kéri
Szabolcs
S
Dibó
György
G
Benedek
György
G
Janka
Zoltán
Z
Vécsei
László
L
Bodis-Wollner
Ivan
I
D000368:Aged; D001288:Attention / Q000502:physiology; D003072:Cognition Disorders / Q000209:etiology / Q000523:psychology*; D004569:Electroencephalography; D004585:Electrooculography; D004594:Electrophysiology; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D014796:Visual Perception / Q000502:physiology*