title: Vulval squamous cell carcinoma arising in localized Darier's disease.
abstract: Darier's disease (keratosis follicularis) is a rare vulval lesion and it has been associated with squamous and non-squamous tumors from different origin. A vulval squamous cell carcinoma (SCC) arising in a localized Darier's disease is presented. To our knowledge, this is the first case to report the association of a vulval SCC and a localized Darier's disease. The possibility of delaying or overlooking the diagnosis of a vulval carcinoma is also illustrated. It is suggested to resect the whole lesion of Darier's disease localized to the vulva or take multiple biopsies.
authors.affiliation: Department of Gynecology, Servicio de Ginecología, Hospital de Jove, Avda. Eduardo Castro s/n, 33290 Gijón, Spain. vazquezj@sego.es
authors.forename: Julio
authors.initials: J
authors.lastname: Vázquez
authors.forename: Cristina
authors.initials: C
authors.lastname: Morales
authors.forename: Luis O
authors.initials: LO
authors.lastname: González
authors.forename: María L
authors.initials: ML
authors.lastname: Lamelas
authors.forename: Andrés
authors.initials: A
authors.lastname: Ribas
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D007644:Darier Disease / Q000150:complications*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D014846:Vulvar Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery