Preoperative chemoembolization for unresectable hepatoblastoma.
Complete surgical resection offers the only chance for cure in patients with hepatoblastoma (HB). Patients with unresectable lesions are given preoperative chemotherapy in an attempt to create a resectable lesion. We present a case of an 11-month-old with an unresectable stage III HB unresponsive to systemic chemotherapy. Transfemoral hepatic-artery chemoembolization resulted in a surgically resectable tumor. The patient underwent a right trisegmentectomy with complete resection of the tumor and remains tumor-free 24 months postoperatively. Salvage chemoembolization can be an effective preoperative modality to convert an unresectable tumor into a resectable one.
Tashjian
David B
DB
Division of Pediatric Surgery, Baystate Medical Center Children's Hospital, Tufts University School of Medicine, Springfield, MA, USA.
Moriarty
Kevin P
KP
Courtney
Richard A
RA
Bean
Mark S
MS
Steele
David A
DA
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D016461:Chemoembolization, Therapeutic; D002945:Cisplatin / Q000008:administration & dosage*; D004317:Doxorubicin / Q000008:administration & dosage*; D018197:Hepatoblastoma / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000601:surgery / Q000628:therapy*; D008297:Male; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed
D004317:Doxorubicin; D002945:Cisplatin