title: [Pancreas-preserving total duodenectomy due to familial adenomatous polyposis in 4 patients].
abstract: In 4 patients with familial adenomatous polyposis (FAP) and multiple severe dysplastic adenomas in the duodenum (a 42-year-old woman and 3 men aged 44, 53 and 33 years, respectively), pancreas-preserving total duodenectomy (PPTD) was carried out. In 2 of the patients, serious early post-operative complications arose (leakage and haemorrhage of the gastrojejunostomy, respectively), and 1 patient developed a late complication (attacks of pancreatitis). During the 1-5-year follow-up period, small villous adenomas were seen in the jejunum (neoduodenum) of 1 of the patients. PPTD is a technically possible procedure which allows targeted treatment to be carried out if duodenum polyps are found upon endoscopic examination.
authors.affiliation: Academisch Ziekenhuis Rotterdam-Dijkzigt, Dr. Molewaterplein 40, 3015 GD Rotterdam.
authors.forename: J L M
authors.initials: JL
authors.lastname: Konsten
authors.forename: G
authors.initials: G
authors.lastname: Kazemier
authors.forename: J
authors.initials: J
authors.lastname: Dees
authors.forename: C H J
authors.initials: CH
authors.lastname: van Eijck
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000601:surgery*; D000328:Adult; D004379:Duodenal Neoplasms / Q000601:surgery*; D004386:Duodenum / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas; D010195:Pancreatitis / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D016896:Treatment Outcome