title: [Non-functional islet-cell tumor: analysis of 237 cases].
abstract: OBJECTIVE
  To summarize the clinical aspects of nonfunctional islet-cell tumor (NIT) reported in Chinese periodicals.
  
  
  METHODS
  Articles in Chinese on NIT were screened from the Chinese Bio-Medical Database (1981.1 - 1999.10). Data of epidemiology, clinical manifestations, diagnosis, defferential diagnosis, and treatment of NIT were analyzed.
  
  
  RESULTS
  60 articles and 237 cases of NIT were selected. The female to male ratio was 2.9:1. Abdominal mass was the most common clinical symptom. It was difficult for the pre-operative diagnosis of NIT and differentiation from pancreatic tumor or retroperitoneal mass. The malignant rate of NIT was 35%. The five-year survival rate of malignant NIT was 53.1%.
  
  
  CONCLUSIONS
  NIT is rare. It occurs more often in female than in male. The preoperative diagnostic rate is rather low. The prognosis of malignant NIT is favorable. Active treatment is strongly recommended.
authors.affiliation: Department of General Surgery, Peking Union Medical College Hospital, Beijing 100730, China.
authors.forename: Zhiying
authors.initials: Z
authors.lastname: Yang
authors.forename: Ping
authors.initials: P
authors.lastname: Zhao
authors.forename: Zhan
authors.initials: Z
authors.lastname: Liu
authors.forename: Weisong
authors.initials: W
authors.lastname: Tang
authors.forename: Shouxian
authors.initials: S
authors.lastname: Zhong
mesh_terms: D007516:Adenoma, Islet Cell / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D018273:Carcinoma, Islet Cell / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy