title: Living related kidney transplantation in a 15-year-old patient with type I hyperoxaluria: a case report.
abstract: The following is a case report of a patient with type I hyperoxaluria who received a living related renal transplant for end-stage renal disease. The deficiency or complete absence of the hepatic enzyme alanine glyoxalate aminotransferase characterizes type I hyperoxaluria. When deficient, an overproduction of oxalate occurs, which then can be deposited in multiple end-organ systems. When performing surgery on a patient with type I hyperoxaluria, the anesthetist needs to be aware that these patients can have a host of problems ranging from cardiovascular anomalies to end-stage renal disease. A careful assessment of each system needs to be performed, along with vigilant planning of the anesthetic regimen. Through proper planning and implementation, a safe and effective anesthetic usually can be performed.
authors.affiliation: Western Pennsylvania Hospital, Pittsburgh, Pa., USA.
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Weir
authors.forename: Jerry
authors.initials: J
authors.lastname: Ciancione
authors.forename: John
authors.initials: J
authors.lastname: O'Donnell
mesh_terms: D000293:Adolescent; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000601:surgery*; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D009719:Nurse Anesthetists