title: [Effects of glutamate on transient outward potassium current of dissociated hippocampal neurons in ca1 sector in rats].
abstract: The effects of glutamate on the transient outward potassium current of dissociated hippocampal CA(1) neurons of 7-10 d rats were studied by the whole-cell patch clamp technique. It was found that glutamate could block the transient potassium current in a dose- and time-dependent manner. The effect was partly voltage-dependent. These results suggest that glutamate may decrease the membrane conductance of K(+) channels in hippocampal neurons.
authors.affiliation: Department of Neurology, Central Hospital of Jiangmen District, Jiangmen 529071.
authors.forename: C Q
authors.initials: CQ
authors.lastname: Xu
authors.forename: Z M
authors.initials: ZM
authors.lastname: Zhang
authors.forename: Z L
authors.initials: ZL
authors.lastname: Xia
authors.forename: C H
authors.initials: CH
authors.lastname: Wu
authors.forename: P A
authors.initials: PA
authors.lastname: Zhou
mesh_terms: D000818:Animals; D004594:Electrophysiology; D005260:Female; D005971:Glutamates / Q000494:pharmacology*; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D009474:Neurons / Q000502:physiology; D015221:Potassium Channels / Q000502:physiology*; D051381:Rats
chemical_list: D005971:Glutamates; D015221:Potassium Channels