title: Description of fourteen new DRB alleles found in a stem cell donor registry.
abstract: Fourteen DRB alleles, DRB1*0705, DRB1*11014, DRB1*1134, DRB1*1136, DRB1*1141, DRB1*1335, DRB1*1337, DRB1*1338, DRB1*1342, DRB1*1343, DRB1*1349, DRB1*1510, DRB3*0105, and DRB5*0103, are described. Among them, eleven are variants which differ by only one nucleotide from previously described alleles, including one silent variant (DRB1*11014). Alleles, DRB1*0705, DRB1*1335 and DRB3*0105, display unique sequence motifs that have never been observed in DRB alleles.
authors.affiliation: Department of Pediatrics, Georgetown University, Washington, DC, USA.
authors.forename: T F
authors.initials: TF
authors.lastname: Tang
authors.forename: Y-S
authors.initials: YS
authors.lastname: Lin
authors.forename: F-M
authors.initials: FM
authors.lastname: Robbins
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.forename: D
authors.initials: D
authors.lastname: Sintasath
authors.forename: G
authors.initials: G
authors.lastname: Coquillard
authors.forename: A
authors.initials: A
authors.lastname: Huang
authors.forename: U
authors.initials: U
authors.lastname: Heine
authors.forename: J
authors.initials: J
authors.lastname: Ng
authors.forename: R J
authors.initials: RJ
authors.lastname: Hartzman
authors.forename: C K
authors.initials: CK
authors.lastname: Hurley
mesh_terms: D000483:Alleles; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D059826:HLA-DRB3 Chains; D059847:HLA-DRB5 Chains; D006801:Humans; D012042:Registries; D017422:Sequence Analysis, DNA; D013234:Stem Cells; D014019:Tissue Donors
chemical_list: D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D059826:HLA-DRB3 Chains; D059847:HLA-DRB5 Chains