Congenital erythrocytosis with increased erythropoietin level.
The term "absolute erythrocytosis" denotes a heterogeneous group of disorders characterized by an increased red blood cell mass. The authors describe a 20-month-old girl with absolute erythrocytosis. Erythropoietin levels were found to be extremely increased, although extensive evaluation failed to reveal a cause for such an inappropriate increase. Of interest is also the documentation of spontaneous erythroid colony formation in the patient's bone marrow cultures. Although such a finding is considered typical of polycythemia vera, the diagnostic criteria of this myeloproliferative disorder were not met.
Athanasiou-Metaxa
Miranda
M
First Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital, Greece. miranda@med.auth.gr
Economou
Marina
M
Tsantali
Chaido
C
Koussi
Afroditi
A
Gombakis
Nikos
N
D001853:Bone Marrow / Q000473:pathology; D003114:Colony-Forming Units Assay; D003937:Diagnosis, Differential; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D005296:Ferrous Compounds / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D018962:Phlebotomy; D011086:Polycythemia / Q000097:blood / Q000151:congenital* / Q000628:therapy
D005296:Ferrous Compounds; D004921:Erythropoietin; C020748:ferrous sulfate