Case report: the management of bone demineralization associated with long-term treatment of multiple paraphilias with long-acting LHRH agonists.
A patient with multiple paraphilias had been successfully treated for 10 years with a long-acting LHRH agonist with complete suppression of deviant sexual activity. However, during treatment, he demonstrated bone demineralization, as documented by serial bone densitometry studies. A treatment regimen was instituted, which resulted in the cessation or partial reversal of bone loss.
Dickey
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Sexual Behaviours Clinic, Gender Identity Clinic, University of Toronto, and Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
D000328:Adult; D018488:Bone Demineralization, Pathologic / Q000139:chemically induced* / Q000175:diagnosis; D015519:Bone Density; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors*; D006801:Humans; D016729:Leuprolide / Q000009:adverse effects*; D008297:Male; D010262:Paraphilic Disorders / Q000188:drug therapy*
D007987:Gonadotropin-Releasing Hormone; D016729:Leuprolide