[Modification of damaging effect of ultraviolet radiation on peritoneal macrophage membranes in mice].
Different factors modificating damaging effect of middle-wave ultraviolet radiation (lambda max = 306 nm) on mice peritoneal macrophage plasma membranes were studied. It was shown that damaging effect of ultraviolet declined when the cells were simultaneously treated by red light (lambda max = 713 nm). This protective effect increased when a red component of light became greater and achieved almost 100% when it consisted 28.6%. It was also found that the decrease in intra- and extracellular pH led to the decrease in damaging effect of UVR. The increase of pH bring to an elevation of UVR destructive effect.
Pirutin
S K
SK
Lomonosov Moscow State University, Biology Faculty, Biophysical Department, Moscow, 119899 Russia. pirutin@aport.ru
Turovetskiĭ
V B
VB
Kudriashov
Iu B
IuB
Rubin
A B
AB
D000584:Amiloride / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000528:radiation effects*; D002478:Cells, Cultured; D006863:Hydrogen-Ion Concentration; D007476:Ionophores / Q000494:pharmacology; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000528:radiation effects*; D051379:Mice; D008985:Monensin / Q000494:pharmacology; D018696:Neuroprotective Agents / Q000494:pharmacology; D011829:Radiation Dosage; D014466:Ultraviolet Rays
D007476:Ionophores; D018696:Neuroprotective Agents; D000584:Amiloride; D008985:Monensin; C039614:ethylisopropylamiloride