Pneumocystis carinii f. sp. hominis is not infectious for SCID mice.
The infectious power of Pneumocystis carinii f. sp. hominis was explored by inoculating SCID mice intranasally with either P. carinii f. sp. hominis or P. carinii f. sp. muris isolates. Only mice inoculated with mouse parasites developed Pneumocystis pneumonia, as assessed by microscopy and PCR. These results suggest that humans do not contract pneumocystosis from animals.
Durand-Joly
Isabelle
I
Ecologie du Parasitisme, Institut Pasteur de Lille, 1 rue du Prof-Calmette-BP 245, 59019 Lille, France. isabelle.joly@pasteur-lille.fr
Aliouat
El Moukhtar
el M
Recourt
Céline
C
Guyot
Karine
K
François
Nadine
N
Wauquier
Michèle
M
Camus
Daniel
D
Dei-Cas
Eduardo
E
D000818:Animals; D006801:Humans; D008253:Macaca mulatta; D051379:Mice; D016513:Mice, SCID; D011010:Pneumocystis / Q000145:classification* / Q000472:pathogenicity; D011020:Pneumonia, Pneumocystis / Q000635:transmission*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D015047:Zoonoses / Q000635:transmission