title: Randomized comparison of remifentanil-propofol with a sciatic-femoral nerve block for out-patient knee arthroscopy.
abstract: OBJECTIVE
  To evaluate preparation and discharge times as well as the anaesthesia-related costs of out-patient knee arthroscopy performed with a combined sciatic-femoral nerve block, or a propofol-remifentanil general anaesthetic.
  
  
  METHODS
  With Ethics Committee approval and written informed consent, 40 healthy patients were pre-medicated with intravenous midazolam (0.05 mg kg(-1)) and ketoprofen (50 mg). They were then randomly allocated to receive either a combined sciatic-femoral nerve block with 25 mL mepivacaine 2% (15 mL for the femoral nerve, 10 mL for the sciatic nerve) (PNB group, n = 20), or a general anaesthetic with a continuous intravenous infusion of remifentanil (0.1-0.3 microgkg(-1) min(-1)) and propofol (target plasma concentration 2-4 microg mL(-1)) with a laryngeal mask airway (GA group, n = 20).
  
  
  RESULTS
  The median (range) preparation time was 16 (10-28)min in the PNB group and 13 (8-22)min in the GA group (P = 0.015). Ten PNB patients were directly discharged to the day-surgery unit after the procedure as compared with one GA patient (P = 0.003). Discharge from the postanaesthesia care unit (PACU) required 5 (5-20) min in the PNB group and 23 (7-95) min in the GA group (P = 0.001). Home discharge criteria were fulfilled after 277 (150-485) min in the PNB group and 170 (100-400) min in the GA group (P = 0.005). Costs related to the time spent in the PACU were lower for the PNB group (1.10 euro, range Euro 0-22 euro) compared with the GA group (30 euro, range 0-176 euro) (P = 0.0005). There were no differences in total costs: PNB group 158 euro (range 105-194 euro) versus GA group 160 euro (range 101-238 euro) (P = 0.61).
  
  
  CONCLUSIONS
  In patients undergoing out-patient knee arthroscopy, the length of stay in the PACU can be shorter after a sciatic-femoral nerve block with a small volume of mepivacaine 2% compared with a propofol-remifentanil anaesthetic, and there is an increased likelihood that they will bypass the first phase of the postoperative recovery.
authors: Vita Salute University, Department of Anaesthesiology, IRCCS H. San Raffaele, Milano, Italy. casati.andrea@hsr.it
authors: A
authors: A
authors: Casati
authors: G
authors: G
authors: Cappelleri
authors: M
authors: M
authors: Berti
authors: G
authors: G
authors: Fanelli
authors: P
authors: P
authors: Di Benedetto
authors: G
authors: G
authors: Torri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General / Q000191:economics; D018686:Anesthetics, Intravenous; D001182:Arthroscopy; D003365:Costs and Cost Analysis; D005260:Female; D005267:Femoral Nerve; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000191:economics; D010880:Piperidines; D015742:Propofol; D011446:Prospective Studies; D011997:Recovery Room; D000077208:Remifentanil; D012584:Sciatic Nerve
chemical_list: D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil; D015742:Propofol