The molecular and supramolecular structures of four 1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazolines.
The supramolecular structures of the title compounds, 2-phenyl-5-p-tolyl-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(23)H(21)N(3), (I), 5-(4-bromophenyl)-2-phenyl-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(22)H(18)BrN(3), (II), 2-(4-chlorophenyl)-5-phenyl-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(22)H(18)ClN(3), (III), and 5-(4-bromophenyl)-2-(4-chlorophenyl)-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(22)H(17)BrClN(3), (IV), are of two general types. Compounds (I), (II) and (III) form base-paired dimers via N-H.N hydrogen bonds, where (I) and (II) are isomorphous, while in (IV), there are no conventional hydrogen bonds.
Low
John Nicolson
JN
Department of Chemistry, University of Aberdeen, Meston Walk, Old Aberdeen AB24 3UE, Scotland. jnlow111@hotmail.com
Cobo
Justo
J
Nogueras
Manuel
M
Sánchez
Adolfo
A
Torres
Harlen
H
Insuasty
Braulio
B
D000596:Amino Acids / Q000037:antagonists & inhibitors; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry; D018360:Crystallography, X-Ray; D019281:Dimerization; D007166:Immunosuppressive Agents / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D011799:Quinazolines / Q000138:chemical synthesis / Q000737:chemistry*
D000596:Amino Acids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D011720:Pyrazoles; D011799:Quinazolines