title: Evidence of a role of endogenous estrogen in the modulation of autonomic nervous system.
abstract: We studied heart rate variability in 14 healthy women before and after oophorectomy compared with 14 matched women who underwent hysterectomy with ovarian conservation. Surgical menopause induced a decline in cardiac vagal modulation with a shift toward sympathetic hyperactivity. Recovery of the baseline condition after 3 months of estrogen replacement therapy in oophorectomized women suggests a role of estrogen in the autonomic nervous control of the cardiovascular system.
authors: Institute of Cardiology, and Department of Obstetrics and Gynecology, University of Cagliari, Sardinia, Italy. mercuro@pacs.unica.it
authors: G
authors: G
authors: Mercuro
authors: A
authors: A
authors: Podda
authors: L
authors: L
authors: Pitzalis
authors: S
authors: S
authors: Zoncu
authors: M
authors: M
authors: Mascia
authors: G B
authors: GB
authors: Melis
authors: G M
authors: GM
authors: Rosano
mesh_terms: D002319:Cardiovascular System / Q000294:innervation; D016022:Case-Control Studies; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000502:physiology*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010052:Ovariectomy; D017698:Postmenopause; D013564:Sympathetic Nervous System / Q000502:physiology*
chemical_list: D004967:Estrogens