A window on the physiopathogenesis of seizures in patients with cortical dysplasia.
Cortical dysplasia is found in many cases of intractable epilepsy. Dr. Avoli reports that dysplastic cortex--removed from human brains during seizure surgery--shows abnormal excitability in vitro.
Avoli
Massimo
M
Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, QC, Canada.
Mattia
Donatella
D
Olivier
Andre
A
D002540:Cerebral Cortex / Q000473:pathology*; D004594:Electrophysiology; D006801:Humans; D019579:Neocortex / Q000473:pathology* / Q000502:physiology* / Q000503:physiopathology; D009474:Neurons / Q000473:pathology*; D012640:Seizures / Q000209:etiology / Q000473:pathology*; D013569:Synapses / Q000473:pathology / Q000502:physiology