Treatment-resistant depression: when antidepressant drug intolerance may indicate food intolerance.
OBJECTIVE
To describe a patient with food intolerance probably contributing to depressive symptoms, intolerance to psychotropic medication and treatment resistance.


METHODS
The case vignette and investigatory procedures are detailed.


RESULTS
The patient's course improved considerably with an elimination diet.


CONCLUSIONS
The prevalence of food intolerance as a contributing factor to depressive disorders requires clarification. Clinicians should be aware of the possible syndrome and that it may be worsened by psychotropic medication.
Parker
Gordon
G
School of Psychiatry, University of New South Wales, Sydney, Australia. g.parker@unsw.edu.au
Watkins
Tim
T
D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D005512:Food Hypersensitivity / Q000209:etiology* / Q000523:psychology*; D006801:Humans; D008297:Male; D017211:Treatment Failure
D000928:Antidepressive Agents