title: New STR at the D5S373 locus and its relevance in human population studies.
abstract: The genetic analysis of a new trinucleotide repeat (D5S373) was carried out with a view to its application in both individual genetic profiling and human population genetics. In a screening analysis from seven world populations (n = 706) and after nucleotide sequence analysis, up to nine alleles were found corresponding to 8-13 repetitions of a TAA motif. This analysis shows He values ranging between 0.689-0.762. D5S373 reveals interpopulational variability which leads to specific frequency profiles in the major human groups, with alleles 8, 11, l2, and 13 being particularly informative, which suggests the that this marker may be of interest in the biological study of human populations.
authors: Departamento de Antropoloxía, Facultade de Bioloxía, Universidade de Santiago de Compostela, Galicia, Spain. bajlbc95@usc.es
authors: J R
authors: JR
authors: Luis
authors: S
authors: S
authors: Dios
authors: J C
authors: JC
authors: Carril
authors: R
authors: R
authors: Herrera
authors: B
authors: B
authors: Caeiro
mesh_terms: D000354:Africa, Western; D000483:Alleles; D001541:Benin; D002681:China; D002895:Chromosomes, Human, Pair 5; D005260:Female; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D008297:Male; D009018:Morocco; D009850:Oman; D017422:Sequence Analysis, DNA; D013030:Spain; D018911:Trinucleotide Repeats / Q000235:genetics*
chemical_list: D005819:Genetic Markers