Ocular applications of povidone-iodine.
Ocular infections can have devastating consequences and may lead to blindness. Povidone-iodine (PVP-I) has many potential advantages over the currently used drugs, including a broader antibacterial spectrum, it turns the surface of the eye brown for a few minutes, bacterial resistance has not been seen and it is cheaper than other agents. PVP-I has made a significant contribution to pre- and postoperative ocular surgical prophylaxis, ophthalmia neonatorum prophylaxis and treatment of bacterial conjunctivitis. Scientific support for these applications includes studies conducted over the past 17 years, which are reviewed.
Isenberg
S J
SJ
Jules Stein Eye Institute, UCLA Medical Center, Los Angeles, Calif 90095, USA.
Apt
L
L
Campeas
D
D
D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000494:pharmacology*; D003234:Conjunctivitis, Bacterial / Q000188:drug therapy*; D005123:Eye / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D009878:Ophthalmia Neonatorum / Q000517:prevention & control*; D011182:Postoperative Care; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000494:pharmacology*; D011300:Preoperative Care
D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine