title: Birth of a healthy baby after transfer of embryos that were cryopreserved for 8.9 years.
abstract: OBJECTIVE
  To report successful pregnancy from embryos that had been cryopreserved for 8.9 years.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Fertility clinic of the University of Buenos Aires School of Medicine.
  
  
  METHODS
  A 43-year-old woman with ovarian failure and a 45-year-old man with nonobstructive azoospermia underwent embryo donation.I NTERVENTION(S): Five embryos that had been cryopreserved and stored since 1989 were thawed in 1998 and donated to an infertile couple. Endometrial preparation was performed with 17beta-estradiol and progesterone. The four embryos with better morphologic characteristics were transferred into the uterus.
  
  
  METHODS
  Post-thaw embryo survival, pregnancy, and birth.
  
  
  RESULTS
  Embryo survival was satisfactory as assessed by morphology. Pregnancy was confirmed by ultrasonography. A healthy baby weighing 2120 g was delivered by cesarean section at 36 weeks.
  
  
  CONCLUSIONS
  Human 8-cell embryos may be viable after extended storage and can result in successful pregnancy.
authors: Halitus Instituto Médico Afiliado a la Facultad de Medicina de la Universidad de Buenos Aires, Buenos Aires, Argentina. cquintans@halitus.com
authors: Carlos J
authors: CJ
authors: Quintans
authors: Mónica J
authors: MJ
authors: Donaldson
authors: María Victoria
authors: MV
authors: Bertolino
authors: Hugo
authors: H
authors: Godoy
authors: R Sergio
authors: RS
authors: Pasqualini
mesh_terms: D000328:Adult; D002585:Cesarean Section; D015925:Cryopreservation; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000502:physiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D036801:Parturition; D011247:Pregnancy; D013997:Time Factors; D016216:Ultrasonography, Prenatal