Enantioselective total synthesis of callipeltoside A.
An asymmetric total synthesis of callipeltoside A has been accomplished highlighted by a catalytic enantioselective vinylogous aldol reaction and a boron-mediated anti-aldol reaction influenced by remote stereocontrol.
Evans
David A
DA
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA. evans@chemistry.harvard.edu
Hu
Essa
E
Burch
Jason D
JD
Jaeschke
Georg
G
D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D019380:Anti-HIV Agents / Q000138:chemical synthesis; D000970:Antineoplastic Agents / Q000138:chemical synthesis; D018942:Macrolides; D011161:Porifera / Q000737:chemistry; D013237:Stereoisomerism
D000900:Anti-Bacterial Agents; D019380:Anti-HIV Agents; D000970:Antineoplastic Agents; D018942:Macrolides; C410329:callipeltoside A