title: An Internet-ready database for prospective randomized clinical trials of high-dose-rate brachytherapy for adenocarcinoma of the prostate.
abstract: OBJECTIVE
  To demonstrate a new interactive Internet-ready database for prospective clinical trials in high-dose-rate (HDR) brachytherapy for prostate cancer.
  
  
  METHODS
  An Internet-ready database was created that allows common data acquisition and statistical analysis. Patient anonymity and confidentiality are preserved. These data forms include all common elements found from a survey of the databases. The forms allow the user to view patient data in a view-only or edit mode. Eight linked forms document patient data before and after receiving HDR therapy. The pretreatment forms are divided into four categories: staging, comorbid diseases, external beam radiotherapy data, and signs and symptoms. The posttreatment forms separate data by HDR implant information, HDR medications, posttreatment signs and symptoms, and follow-up data. The forms were tested for clinical usefulness.
  
  
  CONCLUSIONS
  This Internet-based database enables the user to record and later analyze all relevant medical data and may become a reliable instrument for the follow-up of patients and evaluation of treatment results.
authors: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. pdevlin@lroc.harvard.edu
authors: Phillip M
authors: PM
authors: Devlin
authors: Christina R
authors: CR
authors: Brus
authors: Julia
authors: J
authors: Kazakin
authors: Ronald B
authors: RB
authors: Mitchell
authors: D Jeffrey
authors: DJ
authors: Demanes
authors: Gregory
authors: G
authors: Edmundson
authors: Michael
authors: M
authors: Gribble
authors: Gary S
authors: GS
authors: Gustafson
authors: Douglas A
authors: DA
authors: Kelly
authors: Luis A
authors: LA
authors: Linares
authors: Alvaro A
authors: AA
authors: Martinez
authors: Timothy P
authors: TP
authors: Mate
authors: Subir
authors: S
authors: Nag
authors: Carlos A
authors: CA
authors: Perez
authors: Jaynath G
authors: JG
authors: Rao
authors: Rodney R
authors: RR
authors: Rodriguez
authors: Daniel
authors: D
authors: Shasha
authors: Prabhakar
authors: P
authors: Tripuraneni
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy*; D001918:Brachytherapy; D016208:Databases, Factual; D006801:Humans; D020407:Internet; D008297:Male; D008499:Medical Records; D011446:Prospective Studies; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D016032:Randomized Controlled Trials as Topic; D012984:Software; D014584:User-Computer Interface