[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin].
We describe a case of thoracic aortic aneurysm complicated by chronic disseminated intravascular coagulation (DIC). Initially the DIC was controlled successfully by administration of gabexate mesilate and dalteparin. However, because these drugs were given intravenously, the patient could not be discharged. Subsequently, the DIC was treated successfully by changing to orally administered camostat mesilate, warfarin and aspirin, which allowed the patient to leave hospital.
Fukuda
Naofumi
N
Division of Hematology, Department of Medicine, Yamaguchi Prefecture Central Hospital.
Shimohakamada
Yoko
Y
Nakamori
Yoshitaka
Y
Tominaga
Takayuki
T
Shinohara
Kenji
K
Takahashi
Toru
T
Oeda
Eiichi
E
Sato
Yutaka
Y
D000284:Administration, Oral; D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage*; D017545:Aortic Aneurysm, Thoracic / Q000150:complications / Q000188:drug therapy*; D001241:Aspirin / Q000008:administration & dosage*; D002908:Chronic Disease; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004952:Esters; D016670:Gabexate / Q000031:analogs & derivatives*; D006146:Guanidines / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D014859:Warfarin / Q000008:administration & dosage*
D000925:Anticoagulants; D004952:Esters; D006146:Guanidines; C034532:camostat; D016670:Gabexate; D014859:Warfarin; D001241:Aspirin