title: CTX-m-3 beta-lactamase-producing Escherichia coli from Greece.
abstract: An Escherichia coli clinical strain resistant to all beta-lactams except carbapenems was isolated in a Greek hospital. Analysis of beta-lactamase content by isoelectric focusing, PCR assays specific for various bla genes, and DNA sequencing showed that the strain produced TEM-1, a Citrobacter freundii AmpC-related cephalosporinase, and CTX-M-3. The blaCTX.M-3 gene was carried by a 120-kb plasmid that was readily transferable to a susceptible E. coli host.
authors: Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
authors: A
authors: A
authors: Mavroidi
authors: E
authors: E
authors: Tzelepi
authors: V
authors: V
authors: Miriagou
authors: D
authors: D
authors: Gianneli
authors: N J
authors: NJ
authors: Legakis
authors: L S
authors: LS
authors: Tzouvelekis
mesh_terms: D016971:Citrobacter freundii / Q000235:genetics; D004351:Drug Resistance; D004926:Escherichia coli / Q000201:enzymology*; D004927:Escherichia coli Infections / Q000382:microbiology; D006115:Greece; D006801:Humans; D007525:Isoelectric Focusing; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000737:chemistry / Q000378:metabolism*
chemical_list: C417271:beta-lactamase CTX-M-3; D001618:beta-Lactamases