title: Prognostic significance of the number of leads with ST depression during an anginal attack in high risk patients with unstable angina.
abstract: OBJECTIVE
  We examined the prognostic significance of electrocardiographic predictors (number of leads with ST depression, maximal ST depression, QT dispersion), C-reactive protein, fibrinogen, myosin light chain 1 and creatine kinase MB fraction in 62 patients with unstable angina showing ST depression during an anginal attack.
  
  
  RESULTS
  During the 90-day follow-up period, 15 patients (24%) exhibited new cardiac events (death, myocardial infarction or urgent revascularization). Using multivariate analysis, the number of leads with ST depression [relative risk 6.305 (95% confidence intervals 1.831-21.71), p<0.01] during an anginal attack was found to be an independent risk factor to predict cardiac events. Other predictors did not have prognostic significance.
  
  
  CONCLUSIONS
  The number of leads with ST depression during an anginal attack is an independent risk predictor for new cardiac events in high risk patients with unstable angina.
authors: Department of Internal Medicine, Nishio Municipal Hospital.
authors: Makoto
authors: M
authors: Saitoh
authors: Teruo
authors: T
authors: Kondoh
authors: Kyoko
authors: K
authors: Wakao
authors: Kazuhisa
authors: K
authors: Kitamura
authors: Shigeru
authors: S
authors: Nomoto
authors: Koh
authors: K
authors: Matsuo
authors: Akira
authors: A
authors: Yamada
authors: Tetsuo
authors: T
authors: Yanagawa
mesh_terms: D000368:Aged; D000789:Angina, Unstable / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology; D002097:C-Reactive Protein / Q000378:metabolism; D016001:Confidence Intervals; D017023:Coronary Angiography; D003402:Creatine Kinase / Q000097:blood; D052279:Creatine Kinase, MB Form; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D008297:Male; D015999:Multivariate Analysis; D018994:Myosin Light Chains / Q000097:blood; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors
chemical_list: D005343:Fibrinolytic Agents; D007527:Isoenzymes; D018994:Myosin Light Chains; C076659:myosin light chain I; D005340:Fibrinogen; D002097:C-Reactive Protein; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form