Thermal therapies in interventional MR imaging. Focused ultrasound.
MR image-guided focused ultrasound (FUS) provides an entirely noninvasive approach for local thermal therapies. MR imaging allows target definition and continuous temperature mapping. Therefore, the heating procedure can be controlled spatially and temporally based on automatic feedback to the FUS apparatus. Phased-array ultrasound technology will further help the development. MR imaging/FUS may be applied not only for tissue ablation, but also for local drug delivery, gene therapy, and drug activation.
Moonen
C T
CT
Résonance Magnétique des Systèmes Biologiques, UMR 5536 CNRS/Victor Segalen University Bordeaux 2, Bordeaux, France. moonen@rmsb.u-bordeaux2.fr
Quesson
B
B
Salomir
R
R
Vimeux
F C
FC
de Zwart
J A
JA
van Vaals
J J
JJ
Grenier
N
N
Palussière
J
J
D000818:Animals; D006979:Hyperthermia, Induced; D008279:Magnetic Resonance Imaging; D011817:Rabbits; D015641:Radiography, Interventional; D013552:Swine; D014464:Ultrasonic Therapy