title: A copper-free Sonogashira coupling reaction in ionic liquids and its application to a microflow system for efficient catalyst recycling.
abstract: [reaction: see text] The PdCl2(PPh3)2-catalyzed Sonogashira coupling reaction, in good to high yields, was performed in an ionic liquid ([BMIm][PF6]) in the absence of a copper salt. The use of an ionic liquid allows for the facile separation and recycling of the catalyst. The application of the above reaction in a microflow system in conjunction with an IMM micromixer was also successful.
authors: Department of Chemistry, Faculty of Arts and Sciences, Osaka Prefecture University, Sakai 599-8531, Japan.
authors: Takahide
authors: T
authors: Fukuyama
authors: Masutaka
authors: M
authors: Shinmen
authors: Satoshi
authors: S
authors: Nishitani
authors: Masaaki
authors: M
authors: Sato
authors: Ilhyong
authors: I
authors: Ryu