Corneal endotheliitis and idiopathic sudden sensorineural hearing loss.
OBJECTIVE
To report a case with corneal endotheliitis and idiopathic sudden sensorineural hearing loss, in which herpes simplex virus type 1 DNA was demonstrated in the trabeculum and the aqueous humor by polymerase chain reaction.


METHODS
Interventional case report.


METHODS
A 60-year-old man presented with corneal stromal edema in the right eye and sudden bilateral sensorineural hearing loss. The trabeculum excised during trabeculectomy and the aqueous humor were examined for the presence of herpes simplex virus type 1 DNA by polymerase chain reaction.


RESULTS
Polymerase chain reaction demonstrated herpes simplex virus type 1 DNA in the aqueous humor and the trabeculum.


CONCLUSIONS
Herpes simplex virus type 1 may cause corneal endotheliitis and idiopathic sudden sensorineural hearing loss simultaneously.
Mimura
Tatsuya
T
Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
Amano
Shiro
S
Nagahara
Miyuki
M
Oshika
Tetsuro
T
Tsushima
Kazuhito
K
Nakanishi
Norimasa
N
Tanino
Tsuyoshi
T
D001082:Aqueous Humor / Q000821:virology; D015715:Corneal Edema / Q000209:etiology*; D004279:DNA, Viral / Q000032:analysis; D004728:Endothelium, Corneal / Q000473:pathology*; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D018259:Herpesvirus 1, Human / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D016849:Keratitis, Herpetic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014129:Trabecular Meshwork / Q000821:virology
D004279:DNA, Viral