Electrochemical behavior of thiamine on a self-assembled gold electrode and its square-wave voltammetric determination in pharmaceutical preparations.
The electrochemical behavior of thiamine on a self-assembled electrode of L-cysteine (Cys/SAM/Au) has been investigated and Cys/SAM/Au can be used to detect thiamine using square-wave voltammetry (SWV). At pH 11.40 Britton-Robinson buffer, thiamine exhibits a well-defined anodic peak on Cys/SAM/Au. Under the optimized conditions, the anodic peak current of SWV was linear with the content of thiamine in the range of 1.1 x 10(-8) - 2.2 x 10(-6) mol/L; the detection limit was 5.5 x 10(-9) mol/L. The method was successfully applied to the determination of thiamine in pharmaceutical preparations.
Wan
Qijin
Q
Department of Chemistry, Hubei Normal University, Huangshi, P R China. qijinwan@hs.hb.cninfo.net
Yang
Nianjun
N
Ye
Yongkang
Y
D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods; D004566:Electrodes; D006046:Gold / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D013831:Thiamine / Q000032:analysis* / Q000737:chemistry*
D004364:Pharmaceutical Preparations; D006046:Gold; D013831:Thiamine