Contrast-enhanced high in-plane resolution dynamic MRI of the breast. Are there advantages in comparison to standard dynamic MRI?
OBJECTIVE
To evaluate the diagnostic advantages of high in-plane resolution contrast-enhanced (CE) magnetic resonance imaging (MRI) of the breast in comparison to standard CE-MRI.


METHODS
Forty-one patients with 51 hypervascularized lesions were selected prospectively after undergoing bilateral standard CE MRI (slice thickness 4 mm, in-plane resolution 1.52 x 1.25 mm2, temporal resolution 81 s). Patients underwent high in-plane resolution CE MRI, either (n=21) a two-dimensional fast-low-angle-shot sequence (slice thickness 4 mm, in-plane resolution 0.76 x 0.63 mm2, temporal resolution 96 s) or (n=20) a SE sequence being used (slice thickness 4 mm, in-plane resolution 0.8 x 0.63 mm2, temporal resolution 115 s).


RESULTS
Histopathology revealed 33 malignant and 18 benign lesions (0.2-2.2 cm). Morphologic characteristics were much better visualized with high in-plane resolution. Additional diagnostic information, however, resulted only in one patient with fibroadenoma due to a better visualization of smooth contours.


CONCLUSIONS
High in-plane resolution provides better visualization of morphologic patterns in comparison to standard dynamic MRI. However, a diagnostic advantage is only rare.
Obenauer
Silvia
S
Department of Radiology, Georg-August-University of Göttingen, Robert-Koch-Strasse 40, Germany. soben@med.uni-göttingen.de
Schorn
Corinna
C
Stelter
Bruno
B
Fischer
Uwe
U
Grabbe
Eckhardt
E
D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*
D003287:Contrast Media