title: Possible antitumor promoters in Spinacia oleracea (spinach) and comparison of their contents among cultivars.
abstract: Spinach leaves were found to contain two potent antitumor promoters as detected by the activity against tumor promoter-induced Epstein-Barr virus activation. The active components were identified as 1-O-alpha-linolenoyl-2-O-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-beta-D-galactopyranosyl-sn-glycerol and 1,2-di-O-alpha-linolenoyl-3-O-beta-D-galactopyranosyl-sn-glycerol by spectroscopic data and some chemical and enzymatic reactions. Their contents significantly varied with the cultivar and with the culture conditions.
authors: Department of Biochemistry and Food Science, Faculty of Agriculture, Kagawa University, Japan.
authors: Rong
authors: R
authors: Wang
authors: Toshio
authors: T
authors: Furumoto
authors: Koichiro
authors: K
authors: Motoyama
authors: Katsuichiro
authors: K
authors: Okazaki
authors: Akira
authors: A
authors: Kondo
authors: Hiroshi
authors: H
authors: Fukui
mesh_terms: D016588:Anticarcinogenic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002460:Cell Line; D004354:Drug Screening Assays, Antitumor; D004591:Electrophoresis, Polyacrylamide Gel; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D005990:Glycerol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006017:Glycolipids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000737:chemistry; D013045:Species Specificity; D016339:Spectrometry, Mass, Fast Atom Bombardment; D018724:Spinacia oleracea / Q000737:chemistry*
chemical_list: C419082:1,2-dilinolenoyl-3-galactopyranosylglycerol; C467711:1-O-linolenoyl-2-O-hexadeca-7,10,13-trienoyl-3-O-galactopyranosylglycerol; D016588:Anticarcinogenic Agents; D005960:Glucosides; D006017:Glycolipids; D005990:Glycerol