Matrix metalloproteinases: a tail of a frog that became a prince.
It is 40 years since the first member of what came to be known as the matrix metalloproteinase (MMP) family was described. Structural, molecular and biochemical approaches have subsequently contributed to piecing together the puzzle of how MMPs work, and how they contribute to various disease processes.
Brinckerhoff
Constance E
CE
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.
Matrisian
Lynn M
LM
D000818:Animals; D003001:Cloning, Molecular; D015971:Gene Expression Regulation, Enzymologic; D049673:History, 20th Century; D006801:Humans; D020782:Matrix Metalloproteinases / Q000737:chemistry / Q000235:genetics / Q000266:history / Q000502:physiology*; D008954:Models, Biological; D008958:Models, Molecular; D011480:Protease Inhibitors / Q000627:therapeutic use
D011480:Protease Inhibitors; D020782:Matrix Metalloproteinases