Sequencing of porcine enterovirus groups II and III reveals unique features of both virus groups.
The molecular classification of the porcine enterovirus (PEV) groups II and III was investigated. The sequence of the almost complete PEV-8 (group II) genome reveals that this virus has unique L and 2A gene regions. A reclassification of this group into a new picornavirus genus is suggested. PEV group III viruses are typical enteroviruses. They differ from other enteroviruses by a prolonged stem-loop D of the 5'-cloverleaf structure.
Krumbholz
Andi
A
Institut für Virologie, Klinikum der Friedrich-Schiller-Universität, 07745 Jena, Germany.
Dauber
Malte
M
Henke
Andreas
A
Birch-Hirschfeld
Eckhard
E
Knowles
Nick J
NJ
Stelzner
Axel
A
Zell
Roland
R
D020413:3' Untranslated Regions; D020121:5' Untranslated Regions; D000818:Animals; D001483:Base Sequence; D004771:Enteroviruses, Porcine / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D012367:RNA, Viral; D013552:Swine
D020413:3' Untranslated Regions; D020121:5' Untranslated Regions; D012367:RNA, Viral