title: Crystal engineering of hydroxy group hydrogen bonding: design and synthesis of new diol lattice inclusion hosts.
abstract: The diols 7-11 have been synthesized, and their X-ray crystal structures determined, to learn how to influence and control lattice hydroxy group hydrogen bonding using crystal engineering ideas. To obtain new lattice inclusion hosts precise structural rules can be defined which enable the necessary supramolecular interactions to be duplicated. In this manner the helical tubuland 10 and ellipsoidal clathrate 11 hosts were obtained for the first time and their chloroform inclusion compounds characterized. New synthetic routes were utilized to obtain the bicyclo[3.3.2]decane and 9-thiatricyclo[4.3.1.1(3,8)]undecane frameworks present in these compounds. The solid-state conformations of bicyclo[3.3.2]decane derivatives 9 and 10 are compared with prior predictions and studies made on this uncommon ring system.
authors: School of Chemistry, The University of New South Wales, Sydney 2052, New South Wales, Australia.
authors: Sungho
authors: S
authors: Kim
authors: Roger
authors: R
authors: Bishop
authors: Donald C
authors: DC
authors: Craig
authors: Ian G
authors: IG
authors: Dance
authors: Marcia L
authors: ML
authors: Scudder