Experiments on ion channels at high pressure.
Ion channels are distinctive membrane proteins which provide a gated pathway for diffusing ions. High pressure (<100 MPa) affects the kinetics of gating but not the conductance of the channel. Dynamic structural studies of channels at high pressure are, thus far, conspicuously absent but functional properties are studied at the single channel level with the patch clamp technique.
Macdonald
Alister G
AG
Department of Biomedical Sciences, University of Aberdeen, Scotland, Aberdeen, UK. amacdonald@abdn.ac.uk
D007473:Ion Channels / Q000502:physiology*; D011312:Pressure
D007473:Ion Channels