A case of twin pregnancy with complete hydatidiform mole and coexisting fetus following IVF-ET.
Twin pregnancy consisting of complete hydatidiform mole (H-mole) and a coexisting fetus occurs with an estimated incidence of 1 per 22,000-100,000 pregnancies. The incidence of this unusual twin pregnancy with complete H-mole and a coexisting fetus after in vitro fertilization and embryo transfer (IVF-ET) is not thought to be greater than that of general population. We present an unusual twin pregnancy with complete H-mole and a coexisting fetus that occurred following IVF-ET, which was terminated at 21 weeks of gestation and developed into nonmetastatic gestational trophoblastic tumor.
Kwon
Hye-Eun
HE
Department of Obstetrics and Gynecology, College of Medicine, University of Ulsan, Songpa-Gu, Seoul, South Korea.
Park
Eun-Joo
EJ
Kim
Sung-Hoon
SH
Chae
Hee-Dong
HD
Won
Hye-Sung
HS
Kim
Chung-Hoon
CH
Kang
Byung-Moon
BM
D000032:Abortion, Therapeutic; D000033:Abortion, Threatened / Q000209:etiology; D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D003131:Combined Modality Therapy; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D006828:Hydatidiform Mole / Q000188:drug therapy / Q000628:therapy; D007231:Infant, Newborn; D002955:Leucovorin / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D011272:Pregnancy, Multiple; D014592:Uterine Hemorrhage / Q000209:etiology; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000628:therapy
D000964:Antimetabolites, Antineoplastic; D014408:Biomarkers, Tumor; D018997:Chorionic Gonadotropin, beta Subunit, Human; D002955:Leucovorin; D008727:Methotrexate