title: Apolipoprotein E4 and tau allele frequencies among Choctaw Indians.
abstract: Apolipoprotein genotyping and tau haplotyping were carried out on a series of cases with dementia and controls from the Choctaw Nation of Oklahoma. Both the Apolipoprotein E4 allele frequency and the tau H2 haplotype frequency were low in the Choctaw compared with Caucasians and there was the possibility that the association between dementia and the E4 allele was weaker than in Caucasians.
authors: Department of Health Promotion Sciences, University of Oklahoma, Oklahoma City 73190, USA.
authors: J Neil
authors: JN
authors: Henderson
authors: Richard
authors: R
authors: Crook
authors: Julia
authors: J
authors: Crook
authors: John
authors: J
authors: Hardy
authors: Luisa
authors: L
authors: Onstead
authors: Linda
authors: L
authors: Carson-Henderson
authors: Pat
authors: P
authors: Mayer
authors: Bea
authors: B
authors: Parker
authors: Ronald
authors: R
authors: Petersen
authors: Birdie
authors: B
authors: Williams
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000208:ethnology* / Q000235:genetics* / Q000378:metabolism; D053327:Apolipoprotein E4; D001057:Apolipoproteins E / Q000235:genetics* / Q000378:metabolism; D001921:Brain / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D004252:DNA Mutational Analysis; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005820:Genetic Testing; D005838:Genotype; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009825:Oklahoma / Q000208:ethnology; D044465:White People / Q000235:genetics; D016875:tau Proteins / Q000235:genetics* / Q000378:metabolism
chemical_list: D053327:Apolipoprotein E4; D001057:Apolipoproteins E; D005819:Genetic Markers; D016875:tau Proteins