title: Clinical outcomes of risk-based caries prevention in preschool-aged children.
abstract: OBJECTIVE
  The aim of this study was to evaluate outcomes in young children of risk-based management of dental caries in comparison with routine prevention.
  
  
  METHODS
  The study was carried out in two municipal health centers in Central Finland. The risk-based prevention group consisted of 299 children from Vanha Korpilahti, and the routine prevention group of 226 children from Saarijärvi. The children were 2 yr old at baseline, and they were followed up for 3 yr. All children received regular annual oral health care. In the risk-based prevention group, the presence of mutans streptococci (MS) in plaque (Dentocult-SM strip mutans -test, Orion Diagnostica, Espoo, Finland) and incipient caries lesions were the screening criteria. Additional prevention was targeted at MS-positive subjects twice a year, consisting of health education and application of fluoride varnish. For those who had incipient lesions, 'the high-risk category', additional prevention was given four times a year and this included also chlorhexidine varnish treatments.
  
  
  RESULTS
  The screening and the preventive measures were successfully carried out by specially trained dental assistants. The proportion of children with cavitated caries or fillings was significantly lower in the risk-based than in the routine prevention group. The treatment effect was strongest within the high-risk category: two subjects had to be treated with intensive care for 3 yr to avoid restorative treatment of dental caries by the age of 5 yr in one subject (number needed to treat (NNT) = 2.0; 95% CI 1.4-3.8). The accuracy of screening was evaluated in the routine prevention group and found acceptable.
  
  
  CONCLUSIONS
  The results indicate that in young children, risk-based management of caries seems practical, and prevention of caries can be targeted efficiently to individuals at risk.
authors: Institute of Dentistry, University of Turku, Turku, Finland. kaipie@utu.fi
authors: Kaisu
authors: K
authors: Pienihäkkinen
authors: Jorma
authors: J
authors: Jokela
mesh_terms: D000891:Anti-Infective Agents, Local / Q000008:administration & dosage; D016009:Chi-Square Distribution; D002675:Child, Preschool; D002710:Chlorhexidine / Q000008:administration & dosage; D003731:Dental Caries / Q000517:prevention & control*; D003732:Dental Caries Activity Tests; D003773:Dental Plaque / Q000382:microbiology; D005260:Female; D005460:Fluorides, Topical / Q000008:administration & dosage; D006801:Humans; D016015:Logistic Models; D008297:Male; D008403:Mass Screening; D011313:Preventive Dentistry / Q000379:methods*; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013295:Streptococcus mutans / Q000302:isolation & purification; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D005460:Fluorides, Topical; D002710:Chlorhexidine