[Expression of p-glycoprotein in malignant solid human tumors].
One of the main causes of cancer resistance to chemotherapy is multidrug resistance. The role of P-glyco-protein in different solid human cancers was assessed by taking into account clinico-pathological parameters. The application of inhibitors when multidrug resistance appeared was discussed. The participation of other proteins and enzymes in adding resistance to the cancer cells was stressed.
Grelewski
Piotr G
PG
Katedry i Zakładu immunologii Klinicznej AM we Wrocławiu.
Bar
Julia K
JK
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000378:metabolism*; D018432:Drug Resistance, Multiple; D019008:Drug Resistance, Neoplasm; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism*
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1