title: [A short tandem repeat polymorphism in the inducible nitric oxide synthase gene in Chinese population].
abstract: Polymorphism of the (CCTTT)n repeat, a short tandem repeats (STR) located in promoter region of the inducible nitric oxide synthase (iNOS) gene, was analyzed in a total of 316 Chinese healthy subjects. Twelve alleles and forty-nine genotypes were identified. Three alleles that had not been reported previously, namely 17-repeats, 18-repeats and 19-repeats, were found in Chinese population. Mendelian inheritance of the allele in a family composed of three generations was determined. Some of the observed allele frequency of this STR locus in Chinese differed significantly from that of Caucasians in England.
authors: Department of Biochemistry & Molecular Biology, Institute of Radiation Medicine, Beijing 100850, China. lvx@nic.bmi.ac.cn
authors: Xing
authors: X
authors: Lü
authors: Ping
authors: P
authors: Lu
authors: Rui-Yun
authors: RY
authors: Xing
authors: Qi-Yun
authors: QY
authors: Sun
authors: Ze-Wu
authors: ZW
authors: Qiu
authors: Li
authors: L
authors: Han
authors: Xu-Bin
authors: XB
authors: Zhou
authors: Xiao-Fei
authors: XF
authors: Zheng
mesh_terms: D000293:Adolescent; D000328:Adult; D000483:Alleles; D001483:Base Sequence; D002681:China / Q000208:ethnology; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D019001:Nitric Oxide Synthase / Q000235:genetics*; D052247:Nitric Oxide Synthase Type II; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences; D044465:White People
chemical_list: C496319:NOS2 protein, human; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II