title: Thromboembolism in orthopaedics--observation and experiment.
abstract: Surgical science has evolved from the meticulously recorded anatomical and pathological experiments applied by Hunter to the use of large observational studies and randomised clinical trials. These modern epidemiological techniques, supported by appropriate statistics, are helping us to answer many questions in surgery. Perhaps nowhere in surgery have these techniques been applied as thoroughly as in orthopaedic thromboembolism.
authors: Department of Orthopaedic Surgery, Southampton University Hospitals, UK.
authors: David
authors: D
authors: Warwick
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D016001:Confidence Intervals; D004812:Epidemiologic Methods; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D009140:Musculoskeletal Diseases / Q000453:epidemiology / Q000601:surgery*; D019637:Orthopedic Procedures / Q000009:adverse effects*; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D018401:Sample Size; D013923:Thromboembolism / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight