Right heart obstruction from a balloon-like sinus of Valsalva aneurysm in a patient with Down syndrome.
A 40-year-old man with Down syndrome presented with right heart failure. He was markedly obese and had severe developmental delay. There was marked edema and an early diastolic sound. Transthoracic echocardiography suggested a right heart mass. Transesophageal echocardiography revealed an unruptured balloon-like sinus of Valsalva aneurysm within the right atrium that obstructed the tricuspid orifice. The patient died in hospital of mixed obstructive and/or septic shock.
Lee
S Douglas
SD
St. Michael's Hospital, University of Toronto, Toronto, Canada.
Joseph
Majo
M
Lambert
A Stephane
AS
Mazer
C David
CD
Hutchison
Stuart J
SJ
D000328:Adult; D001014:Aortic Aneurysm / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004314:Down Syndrome; D017548:Echocardiography, Transesophageal; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D012850:Sinus of Valsalva; D018497:Ventricular Dysfunction, Right / Q000209:etiology*; D014694:Ventricular Outflow Obstruction / Q000209:etiology*