Randomized clinical trials of combined estrogen-androgen preparations: effects on sexual functioning.
OBJECTIVE
To review the randomized controlled trials of the efficacy of combined estrogen-androgen (E-A) preparations on sexual functioning in postmenopausal women.


METHODS
Naturally and surgically menopausal women.


METHODS
Changes in aspects of sexual functioning.


RESULTS
In general, a high degree of agreement exists among the findings of these well-controlled trials that combined E-A preparations enhance psychological well-being as well as sexual desire and interest and, sometimes, increases the frequency of sexual intercourse and orgasm compared with estrogen-alone treatment in both naturally and surgically postmenopausal women.


CONCLUSIONS
In selected cases, combined E-A therapy can enhance the quality of life for both naturally and surgically postmenopausal women.
Sherwin
Barbara B
BB
Departments of Psychology and Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada. bsherwin@ego.psych.mcgill.ca
D000728:Androgens / Q000494:pharmacology*; D000818:Animals; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007989:Libido / Q000187:drug effects* / Q000502:physiology; D017698:Postmenopause / Q000187:drug effects* / Q000502:physiology; D016032:Randomized Controlled Trials as Topic; D012725:Sexual Behavior / Q000187:drug effects* / Q000502:physiology / Q000523:psychology
D000728:Androgens; D004967:Estrogens