title: Ulcerative colitis complicating pseudomembranous colitis of the right colon.
abstract: A 65-year-old man in the remission stage of ulcerative colitis developed severe bloody diarrhea and high fever. He was treated with imipenem/cilastatin and clindamycin for infectious enterocolitis at a local hospital, but there was no improvement in his condition. Steroid pulse therapy was also ineffective. Colonoscopy revealed pseudomembranous colitis extending from the ascending colon to the cecum, and Clostridium difficile toxin was positive in the feces. The administration of vancomycin in addition to oral steroids resulted in rapid improvement of the condition. Total colonoscopy is recommended for precise diagnosis when patients with ulcerative colitis develop intractable diarrhea during or after antibiotic therapy.
authors: Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
authors: Aiping
authors: A
authors: Wang
authors: Fuminao
authors: F
authors: Takeshima
authors: Maho
authors: M
authors: Ikeda
authors: Ken
authors: K
authors: Ohnita
authors: Hisashi
authors: H
authors: Furusu
authors: Hajime
authors: H
authors: Isomoto
authors: Yohei
authors: Y
authors: Mizuta
authors: Kunihiko
authors: K
authors: Murase
authors: Ikuo
authors: I
authors: Murata
authors: Shigeru
authors: S
authors: Kohno
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D003106:Colon / Q000473:pathology; D003113:Colonoscopy; D004761:Enterocolitis, Pseudomembranous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents