title: Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria.
abstract: Levels of soluble CD30 (sCD30) in serum were elevated in patients with Plasmodium falciparum malaria but showed decline following treatment. The levels of sCD30 in serum were correlated significantly with the expression of gamma interferon by peripheral T cells. These data suggest that CD30(+) cells are upregulated during a malaria attack and that they may play a regulating role at the site of inflammation.
authors: Center for Medical Parasitology, Department of Infectious Diseases, Copenhagen University Hospital and Institute for Medical Microbiology and Immunology, University of Copenhagen, Copenhagen, Denmark. kkcmp@rh.dk
authors: Kåre
authors: K
authors: Kemp
authors: Jørgen A L
authors: JA
authors: Kurtzhals
authors: Bartholomew D
authors: BD
authors: Akanmori
authors: Victoria
authors: V
authors: Adabayeri
authors: Bamenla Q
authors: BQ
authors: Goka
authors: Charlotte
authors: C
authors: Behr
authors: Lars
authors: L
authors: Hviid
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002648:Child; D005869:Ghana; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis; D017730:Ki-1 Antigen / Q000097:blood*; D016778:Malaria, Falciparum / Q000097:blood / Q000276:immunology*; D010963:Plasmodium falciparum / Q000276:immunology; D012995:Solubility; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology
chemical_list: D017730:Ki-1 Antigen; D007371:Interferon-gamma