title: Structure and function of the eukaryotic ribosome: the next frontier.
abstract: As the catalytic and regulatory centers of protein synthesis in cells, ribosomes are central to many aspects of cell and structural biology. Recent work highlights the unique properties and complexity of eukaryotic ribosomes and their component rRNAs and proteins.
authors: Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, CT 06520, USA. jennifer.doudna@yale.edu
authors: Jennifer A
authors: JA
authors: Doudna
authors: Virginia L
authors: VL
authors: Rath
mesh_terms: D000818:Animals; D020134:Catalytic Domain / Q000235:genetics; D005057:Eukaryotic Cells / Q000378:metabolism*; D006801:Humans; D007425:Intracellular Membranes / Q000201:enzymology / Q000648:ultrastructure; D015394:Molecular Structure; D014176:Protein Biosynthesis / Q000235:genetics*; D011506:Proteins / Q000235:genetics / Q000648:ultrastructure; D012335:RNA, Ribosomal / Q000235:genetics* / Q000648:ultrastructure; D012269:Ribosomal Proteins / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure; D012270:Ribosomes / Q000201:enzymology / Q000235:genetics* / Q000648:ultrastructure; D018406:Virus Physiological Phenomena
chemical_list: D011506:Proteins; D012335:RNA, Ribosomal; D012269:Ribosomal Proteins