Prognostic significance of the number of leads with ST depression during an anginal attack in high risk patients with unstable angina.
OBJECTIVE
We examined the prognostic significance of electrocardiographic predictors (number of leads with ST depression, maximal ST depression, QT dispersion), C-reactive protein, fibrinogen, myosin light chain 1 and creatine kinase MB fraction in 62 patients with unstable angina showing ST depression during an anginal attack.


RESULTS
During the 90-day follow-up period, 15 patients (24%) exhibited new cardiac events (death, myocardial infarction or urgent revascularization). Using multivariate analysis, the number of leads with ST depression [relative risk 6.305 (95% confidence intervals 1.831-21.71), p<0.01] during an anginal attack was found to be an independent risk factor to predict cardiac events. Other predictors did not have prognostic significance.


CONCLUSIONS
The number of leads with ST depression during an anginal attack is an independent risk predictor for new cardiac events in high risk patients with unstable angina.
Saitoh
Makoto
M
Department of Internal Medicine, Nishio Municipal Hospital.
Kondoh
Teruo
T
Wakao
Kyoko
K
Kitamura
Kazuhisa
K
Nomoto
Shigeru
S
Matsuo
Koh
K
Yamada
Akira
A
Yanagawa
Tetsuo
T
D000368:Aged; D000789:Angina, Unstable / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology; D002097:C-Reactive Protein / Q000378:metabolism; D016001:Confidence Intervals; D017023:Coronary Angiography; D003402:Creatine Kinase / Q000097:blood; D052279:Creatine Kinase, MB Form; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D008297:Male; D015999:Multivariate Analysis; D018994:Myosin Light Chains / Q000097:blood; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors
D005343:Fibrinolytic Agents; D007527:Isoenzymes; D018994:Myosin Light Chains; C076659:myosin light chain I; D005340:Fibrinogen; D002097:C-Reactive Protein; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form