title: Magnesium bioavailability from mineral water. A study in adult men.
abstract: OBJECTIVE
  To assess magnesium enteral absorption from a magnesium-rich mineral water.
  
  
  METHODS
  Experimental study.
  
  
  METHODS
  Department of Nuclear Medicine, Brugmann Hospital, Brussels, Belgium.
  
  
  METHODS
  Ten healthy male volunteers in the age range 25-42 y.
  
  
  METHODS
  Each subject completed two sessions in a random order. At one session, they received an oral load of 300 ml of water (containing 1.2 mmol Mg), traced with (28)Mg, and at the other session they received an intravenous injection of (28)Mg, in order to take into account the metabolism of endogenous magnesium. The dietary consumption was further noted on a weekly diary.
  
  
  RESULTS
  The mean bioavailability was 59.1% (s.d.+/-13.6). Magnesium absorption and age were significantly inversely correlated (r=-0.68, P=0.035).
  
  
  CONCLUSIONS
  Magnesium-rich mineral water is a reliable source of magnesium. Our observation of decreased magnesium absorption with age deserves further investigations.
  
  
  BACKGROUND
  The study was sponsored by SEV, Bourg la Reine, France.
authors: Department of Nuclear Medicine, CHU Brugmann-Free University of Brussels, Brussels, Belgium. mverhas@pop.vub.ac.be
authors: M
authors: M
authors: Verhas
authors: V
authors: V
authors: de la Guéronnière
authors: J-M
authors: JM
authors: Grognet
authors: J
authors: J
authors: Paternot
authors: A
authors: A
authors: Hermanne
authors: P
authors: P
authors: Van den Winkel
authors: R
authors: R
authors: Gheldof
authors: P
authors: P
authors: Martin
authors: M
authors: M
authors: Fantino
authors: Y
authors: Y
authors: Rayssiguier
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000367:Age Factors; D001682:Biological Availability; D006801:Humans; D007275:Injections, Intravenous; D007408:Intestinal Absorption / Q000502:physiology*; D007553:Isotope Labeling; D008274:Magnesium / Q000493:pharmacokinetics*; D008297:Male; D008900:Mineral Waters / Q000032:analysis*
chemical_list: D008900:Mineral Waters; D008274:Magnesium