Successful planned pregnancy in a patient with St Jude medical prosthetic mitral valve.
A primiparous woman with a St Jude Medical (SJM) mitral valve prosthesis and receiving anticoagulant drug delivered a healthy male infant by spontaneous normal vaginal delivery. Oral warfarin was replaced by subcutaneous heparin at the 6th week of gestation and the dosage of heparin was adjusted to maintain a partial thromboplastin time between 2.0 and 2.5 times the control value. Treatment with heparin was administered during the first trimester and the last 5 weeks of gestation. Warfarin was used between the 13th and 32nd week. Successful pregnancy and delivery in patients with a SJM mitral valve prostheses is possible with careful maintenance of anticoagulation.
Fukuda
Tsuyoshi
T
Division of Pediatric Cardiology, Kinki University School of Medicine, Osaka, Japan. fukuda@kpcd.med.kindai.ac.jp
Yokoyama
Tatsuo
T
Otaki
Masaki
M
Oku
Hidetaka
H
Shiina
Masami
M
Umemoto
Masahiko
M
D000328:Adult; D002648:Child; D005193:Family Planning Services / Q000379:methods*; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007231:Infant, Newborn; D008943:Mitral Valve; D011247:Pregnancy; D011256:Pregnancy Outcome