title: SUMO wrestling with specificity.
abstract: A new structure reveals how substrates are recognized for conjugation to the ubiquitin-like protein SUMO, a posttranslational modification that functions in activation of transcription factors, nuclear import, and cell division.
authors: Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132, USA.
authors: Andrew P
authors: AP
authors: VanDemark
authors: Christopher P
authors: CP
authors: Hill
mesh_terms: D001665:Binding Sites; D020690:GTPase-Activating Proteins / Q000737:chemistry* / Q000378:metabolism; D008025:Ligases / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D025842:SUMO-1 Protein / Q000737:chemistry* / Q000378:metabolism; D025801:Ubiquitin / Q000378:metabolism; D044763:Ubiquitin-Conjugating Enzymes; D000098843:Ubiquitin-Conjugating Enzyme UBC9
chemical_list: D020690:GTPase-Activating Proteins; D025842:SUMO-1 Protein; D025801:Ubiquitin; D044763:Ubiquitin-Conjugating Enzymes; D008025:Ligases; D000098843:Ubiquitin-Conjugating Enzyme UBC9