Fat targets for insulin signaling.
Adipose cells control flux of fatty acids to peripheral tissues by storing and hydrolyzing triglyceride under hormonal control. New data reveal that insulin may regulate this process in part by promoting membrane trafficking of intracellular fatty acid transporters FATP1 and FATP4 to the plasma membrane.
Czech
Michael P
MP
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
D017667:Adipocytes / Q000187:drug effects / Q000502:physiology*; D018955:CD36 Antigens; D050612:Fatty Acid Transport Proteins; D005227:Fatty Acids / Q000378:metabolism*; D006801:Humans; D007328:Insulin / Q000502:physiology*; D008562:Membrane Glycoproteins / Q000378:metabolism; D027361:Organic Anion Transporters / Q000378:metabolism
D018955:CD36 Antigens; D050612:Fatty Acid Transport Proteins; D005227:Fatty Acids; D007328:Insulin; D008562:Membrane Glycoproteins; D027361:Organic Anion Transporters; C493572:Slc27a4 protein, mouse