Towards genomic and proteomic studies of protein phosphorylation in plant-pathogen interactions.
Phosphorylation is an effective method of post-translational protein modification but understanding its significance is hindered by its biological complexity. Many protein kinases and phosphatases have been identified that connect signal perception mechanisms to plant defence responses. Recent studies of mitogen-activated protein kinases, calcium-dependent protein kinases and other kinases and phosphatases have revealed some important mechanisms, but have also raised new questions. The regulation of any phosphorylation pathway is complex and dynamic. There are many protein kinases and phosphatases in the plant genome, which makes it hard to delineate the phosphorylation machinery fully. Genomics and proteomics have already identified new components and will continue to influence the study of phosphorylation profoundly in plant-pathogen interactions.
Xing
Tim
T
Agriculture and Agri-Food Canada, Cereal Research Centre, Manitoba, R3T 2M9, Winnipeg, Canada. xingtx@em.agr.ca
Ouellet
Thérèse
T
Miki
Brian L
BL
D001419:Bacteria / Q000254:growth & development; D005658:Fungi / Q000254:growth & development; D005818:Genetic Engineering; D018745:Genome, Plant; D023281:Genomics / Q000379:methods*; D007113:Immunity, Innate / Q000235:genetics; D020929:Mitogen-Activated Protein Kinase Kinases / Q000235:genetics / Q000378:metabolism; D020928:Mitogen-Activated Protein Kinases / Q000235:genetics / Q000378:metabolism; D010766:Phosphorylation; D010935:Plant Diseases / Q000235:genetics / Q000382:microbiology; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism* / Q000382:microbiology; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism; D020543:Proteome / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D015003:Yeasts / Q000254:growth & development
D010940:Plant Proteins; D020543:Proteome; D011494:Protein Kinases; D020928:Mitogen-Activated Protein Kinases; D020929:Mitogen-Activated Protein Kinase Kinases