title: Peripheral giant cell granuloma: a case report.
abstract: The peripheral giant cell granuloma is a reactive lesion of the soft tissue of the oral cavity. Clinical appearance ranges from normal tissue coloration to dark red or purplish. These are elevated lesions generally 5-15 mm in diameter. Etiology is considered to be chronic irritation. To decrease the risk of clinical recurrence, treatment is complete excision to include the underlying periosteum. Histologic features of the peripheral giant cell granuloma include multinucleated giant cells with a stroma that may contain osteoblasts, myofibroblasts, macrophages, and Langerhans cells. A case report is presented.
authors: Naval Dental Center, Pearl Harbor, Hawaii, USA. ldbreault@earthlink.net
authors: L G
authors: LG
authors: Breault
authors: E B
authors: EB
authors: Fowler
authors: M J
authors: MJ
authors: Wolfgang
authors: D M
authors: DM
authors: Lewis
mesh_terms: D000328:Adult; D003116:Color; D003728:Dental Calculus / Q000150:complications; D015726:Giant Cells / Q000473:pathology; D005882:Gingival Diseases / Q000473:pathology*; D006097:Granulation Tissue / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000473:pathology*; D006485:Hemosiderin / Q000032:analysis; D006801:Humans; D006965:Hyperplasia; D008297:Male; D010521:Periosteum / Q000601:surgery; D012008:Recurrence; D012307:Risk Factors
chemical_list: D006485:Hemosiderin