Impairment of constructive memory in schizophrenia.
Episodic memories are characterized by a specific state of awareness, conscious recollection, which allows subjects to mentally relive past events. They are not a literal reproduction of the past but instead depend on constructive processes. Patients with schizophrenia exhibit a specific impairment of conscious recollection. The aim of this study was to investigate the role of constructive processes into defective conscious recollection of patients with schizophrenia. An experiential approach to false recognition and related states of awareness was used. Thirty patients with schizophrenia, who were matched with 30 normal subjects, studied lists of words semantically related to a non-presented theme word (critical lure). On a recognition memory task with both previously presented words and non presented critical lures, they were asked to give Remember, Know or Guess responses to items that were recognized on the basis of conscious recollection, familiarity or guessing, respectively. Patients with schizophrenia recognized fewer studied words and critical lures than normal subjects. This deficit was restricted to memories associated with conscious recollection as indicated by a decrease in Remember responses, but not Know and Guess responses. Our results indicate that patients with schizophrenia exhibit an impaired conscious recollection, whether memories are true or false. They provide evidence that schizophrenia impairs the mere construction of conscious recollection.
Huron
Caroline
C
CNRS UMR 7593, Pavillon Clérambault, Hôpital de la Salpétrière, Paris, France.
Danion
Jean-Marie
JM
D000328:Adult; D003243:Consciousness; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000209:etiology* / Q000523:psychology*; D012094:Repression, Psychology; D012559:Schizophrenia / Q000150:complications*