Synthesis and biological evaluation of S-glycosylated pyridines.
The formation of thioglycosides 7a-j and 10a-j via the reaction of sodium salts of thiopyridines 3a-e with glycosyl bromides 6a,b has been studied. Comparison with the products obtained from silylated thiopyridines 8a-e and peracetylated sugars 9a,b is made. 13C NMR was utilized to elucidate the proposed structures of the products.
Attia
Adel M E
AM
Department of Chemistry, Faculty of Education, University of Tanta (Kafr El-Sheikh Branch), Egypt.
D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000494:pharmacology; D002460:Cell Line; D006031:Glycosylation; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology
D019380:Anti-HIV Agents; D011725:Pyridines