title: Evaluation of high temperature glycation of proteins and peptides by electrospray ionization mass spectrometry.
abstract: Recently Boratyński & Roy (Glycoconjugate J., 1998, 15, 131) described a fast and convenient procedure for the synthesis of glycoconjugates. In the present study we used ESI-MS and circular dichroism as tools to analyze non-enzymatic glycation products of proteins and peptides. We discuss influence of reaction conditions on the rate of glycation of lysozyme. We analyze for the first time collision induced dissociation spectra of the obtained peptide conjugates.
authors: Faculty of Chemistry, University of Wrocław, Poland. stp@wchuwr.chem.uni.wroc.pl
authors: P
authors: P
authors: Stefanowicz
authors: J
authors: J
authors: Boratyński
authors: U
authors: U
authors: Kańska
authors: I
authors: I
authors: Petry
authors: Z
authors: Z
authors: Szewczuk
mesh_terms: D002942:Circular Dichroism; D005998:Glycine / Q000737:chemistry; D008956:Models, Chemical; D009113:Muramidase / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D013696:Temperature
chemical_list: D010455:Peptides; D011506:Proteins; D009113:Muramidase; D005998:Glycine