title: In vitro antiplasmodial activity of extracts of Argentinian plants.
abstract: Fifteen extracts from nine selected Argentine medicinal plants were tested for their antiplasmodial activity in vitro by assessing their ability to inhibit the uptake of [3H]-hypoxanthine into the Plasmodium falciparum K1 pyrimethamine/chloroquine resistant strain. The methanol extract of Satureja parvifolia showed good antiplasmodial activity (IC(50) 3 microg/ml). Inhibition of the growth of P. falciparum was also observed with aqueous extracts of Buddleja globosa and S. parvifolia.
authors: IQUJMEFA (UBA-CONICET), Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junin 956, Buenos Aires, Argentina.
authors: S
authors: S
authors: Debenedetti
authors: L
authors: L
authors: Muschietti
authors: C
authors: C
authors: van Baren
authors: M
authors: M
authors: Clavin
authors: A
authors: A
authors: Broussalis
authors: V
authors: V
authors: Martino
authors: P J
authors: PJ
authors: Houghton
authors: D
authors: D
authors: Warhurst
authors: J
authors: J
authors: Steele
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D001118:Argentina; D004351:Drug Resistance; D020128:Inhibitory Concentration 50; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D010963:Plasmodium falciparum / Q000187:drug effects*
chemical_list: D000962:Antimalarials; D010936:Plant Extracts