Novel synthesis of 2-arylbenzothiazoles mediated by ceric ammonium nitrate (CAN).
[reaction: see text] Cyclization of the intermediate radical formed after initial oxidative coupling between thiophenols and aromatic nitriles leads to the synthesis of a wide range of 2-arylbenzothiazoles.
Tale
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School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Vishnupuri, Nanded-431606, Maharashtra, India. rhtale1@rediffmail.com
D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D052160:Benzothiazoles; D007202:Indicators and Reagents; D009566:Nitrates / Q000737:chemistry; D016877:Oxidants; D010084:Oxidation-Reduction; D013844:Thiazoles / Q000138:chemical synthesis*
D000970:Antineoplastic Agents; D052160:Benzothiazoles; D007202:Indicators and Reagents; D009566:Nitrates; D016877:Oxidants; D013844:Thiazoles; C005465:benzothiazole; C006568:ammonium nitrate