title: Toward an analogue of the transition state of preD3-D3 isomerization: stereoselective synthesis of linearly fused 6-8-6 carbocyclic systems.
abstract: [reaction: see text] A stereoselective synthesis of 6-8-6 fused carbocyclic systems based on enol alkylation, ketone allylation, RCM, and Heck cyclization was developed to obtain compounds with a carbon framework that mimics the putative transition structure of the isomerization of previtamin D3 to vitamin D3.
authors: Departamento de Química Orgánica e Unidade Asociada ó C.S.I.C., Facultade de Química, Universidade de Santiago, 15782 Santiago de Compostela, Spain.
authors: Eva M
authors: EM
authors: Codesido
authors: J Ramón
authors: JR
authors: Rodríguez
authors: Luis
authors: L
authors: Castedo
authors: Juan R
authors: JR
authors: Granja
mesh_terms: D002762:Cholecalciferol / Q000031:analogs & derivatives* / Q000737:chemistry*; D007202:Indicators and Reagents; D007536:Isomerism; D008958:Models, Molecular; D010084:Oxidation-Reduction; D011084:Polycyclic Aromatic Hydrocarbons / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007202:Indicators and Reagents; D011084:Polycyclic Aromatic Hydrocarbons; D002762:Cholecalciferol; C025168:previtamin D(3)