title: Perioperative features of coronary artery bypass grafting in patients aged 75 years or older.
abstract: OBJECTIVE
  Coronary artery bypass grafting (CABG) is well established as an effective operation to overcome ischemic heart disease; however, the number of aged patients with a high operative risk undergoing this procedure has increased in recent years. This retrospective study evaluates our experience of performing CABG in a consecutive series of patients aged 75 years or older.
  
  
  METHODS
  To assess the hospital mortality and morbidity associated with this procedure, we retrospectively analyzed 49 patients aged 75 years or older (Elderly Group) who underwent CABG and compared the results with those of 88 patients aged 65-74 years (Control Group) who underwent CABG during the same period. Patients were examined for cerebrovascular diseases, and those with significant stenosis underwent pulsatile cardiopulmonary bypass. To avoid pulmonary complications, patients were extubated early.
  
  
  RESULTS
  The Control Group had a significantly higher incidence of arterial grafts than the Elderly Group (0.8 +/- 0.5 versus 0.3 +/- 0.5; p < 0.0001). The Elderly Group had a significantly higher incidence of postoperative complications than the Control Group, with supraventricular arrhythmia in 57.1% versus 28.4%, (p = 0.0009), delirium in 36.7% versus 11.4%, (p = 0.0004), pneumonia in 6.1% versus 0%, (p = 0.0439), and intubation duration of 88.3 +/- 212.5 hours versus 37.2 +/- 92 hours (p = 0.0296), respectively. However, there was no significant difference in hospital mortality between the two groups, being 8.2% versus, 2.3%, in the Elderly group and Control Group, respectively (p = 0.1867).
  
  
  CONCLUSIONS
  These findings indicated that when elderly patients were appropriately managed, CABG could be performed with an acceptably low risk to mortality.
authors: First Department of Surgery, Yamaguchi University School of Medicine, Minami-Kogushi, Ube, Yamaguchi 755-8505, Japan.
authors: Toshiro
authors: T
authors: Kobayashi
authors: Kimikazu
authors: K
authors: Hamano
authors: Akihito
authors: A
authors: Mikamo
authors: Haruhiko
authors: H
authors: Okada
authors: Hidenori
authors: H
authors: Gohra
authors: Masaki
authors: M
authors: Miyamoto
authors: Tatsuro
authors: T
authors: Oda
authors: Kensuke
authors: K
authors: Esato
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass / Q000401:mortality; D017558:Elective Surgical Procedures; D004630:Emergencies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D009203:Myocardial Infarction / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome