Congenital hemihypertrophy and pheochromocytoma, not a coincidental combination?
We describe a 19-year-old female, known to have congenital hemihypertrophy, who presented with bilateral benign pheochromocytoma. This is the second time that this combination has been reported in the literature. We speculate that the combination of congenital hemihypertrophy and pheochromocytoma is not coincidental and could be part of the clinical spectrum of the Beckwith-Wiedemann syndrome.


CONCLUSIONS
in patients with congenital hemihypertrophy, the physician should be aware of the symptoms of pheochromocytoma. Besides screening for abdominal tumours, analysis of plasma and/or urinary catecholamines and/or their metabolites should be considered.
van den Akker
Erica L T
EL
Department of Paediatric Endocrinology, Sophia Childrens Hospital, Erasmus University Medical Centre, Rotterdam, The Netherlands. vandenakker@alkg-azr.nl
de Krijger
Ronald R
RR
de Herder
Wouter W
WW
Drop
Stenvert L S
SL
D000306:Adrenal Cortex Neoplasms / Q000473:pathology; D000311:Adrenal Glands / Q000473:pathology*; D000328:Adult; D001506:Beckwith-Wiedemann Syndrome / Q000473:pathology*; D002395:Catecholamines / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000151:congenital; D010673:Pheochromocytoma / Q000097:blood / Q000473:pathology* / Q000652:urine
D002395:Catecholamines