Obsessive-compulsive disorder (OCD) patients are impaired in remembering temporal order and in judging their own performance.
Obsessive-compulsive disorder (OCD) has been related to frontostriatal dysfunction, but some inconsistencies between studies and a relative paucity of neuropsychological research still characterizes the study of OCD. We compared 28 patients with OCD and matched healthy controls on two neuropsychological tests sensitive to frontal dysfunction: temporal ordering and a "feeling-of-doing" (FOD) judgment about ordering. The OCD group performed significantly worse than controls in the temporal ordering task despite showing normal recognition memory. Patients were also impaired in "feeling-of-doing" judgments suggesting they have a lack of self-awareness of their performance. Thus, the results of the current study reinforces previous research that indicates that OCD patients fail on tasks that require adequate functioning of the frontal-striatal pathways.
Jurado
M A
MA
Dpt. Psiquiatria i Psicobiologia clínica, Universitat de Barcelona, Spain. ajurado@psi.ub.es
Junqué
C
C
Vallejo
J
J
Salgado
P
P
Grafman
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D001364:Awareness / Q000502:physiology*; D003342:Corpus Striatum / Q000503:physiopathology; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D009434:Neural Pathways / Q000503:physiopathology; D009483:Neuropsychological Tests; D009771:Obsessive-Compulsive Disorder / Q000503:physiopathology* / Q000523:psychology; D012647:Self-Assessment; D012691:Serial Learning / Q000502:physiology*; D014706:Verbal Learning / Q000502:physiology