title: Ileal perforation in diffuse intestinal Behçet disease: report of a case.
abstract: Intestinal ulcers in Behçet disease tend to cause perforation, and postoperative recurrence is common with a high mortality rate. The optimal therapeutic strategy has yet to be elucidated, particularly in cases of diffuse intestinal involvement. We herein present a case of diffuse intestinal Behçet disease with ileal perforation. A 57-year-old Japanese woman was referred to our institution with complaints of intractable oral ulcers and abdominal pain. The patient underwent an emergency laparotomy for perforated peritonitis in spite of the intravenous administration of prednisolone (1.5 mg/kg) under total parenteral nutrition. Macroscopically, an inflamed ileum measuring 1.6 m in length was resected, including a 1-cm perforated ulceration. Innumerable small and deep ulcers were also observed, consisting of nonspecific inflammation. The patient has been free from any recurrence of intestinal ulcers while being treated with prednisolone, colchicine, and a low-residue diet for 1.5 years.
authors: Department of Internal Medicine, Kyushu Central Hospital, Fukuoka, Japan.
authors: Kazuoki
authors: K
authors: Hizawa
authors: Hidenobu
authors: H
authors: Kai
authors: Hirofumi
authors: H
authors: Hasegawa
authors: Tsukane
authors: T
authors: Nakahara
authors: Kimihiro
authors: K
authors: Akagi
authors: Keiichiro
authors: K
authors: Iwai
authors: Sadafumi
authors: S
authors: Tamiya
authors: Takayuki
authors: T
authors: Matsumoto
mesh_terms: D001528:Behcet Syndrome / Q000150:complications* / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000209:etiology* / Q000628:therapy; D007410:Intestinal Diseases / Q000209:etiology / Q000628:therapy; D007416:Intestinal Perforation / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D014456:Ulcer / Q000209:etiology / Q000628:therapy