title: Postorgasmic illness syndrome: two cases.
abstract: We describe the symptoms of a postejaculatory syndrome in two men with spontaneous ejaculations. The syndrome consists of severe fatigue, intense warmth, and a flulike state, with generalized myalgia. These symptoms occur rapidly after ejaculation and only disappear after 4 to 7 days. The symptoms are so severe that sexual activity is avoided. The cluster of symptoms is named postorgasmic illness syndrome (POIS). To date, no explanation has been offered for the etiology and pathogenesis of the symptoms, and the prevalence is unknown. Both cases are presented to draw attention to this syndrome for further research regarding etiology, pathogenesis, and treatment.
authors: Department of Psychiatry and Neurosexology, Leyenburg Hospital, Leyweg 275, 2545 CH The Hague, The Netherlands. post@m-waldinger.demon.nl
authors: Marcel D
authors: MD
authors: Waldinger
authors: Dave H
authors: DH
authors: Schweitzer
mesh_terms: D000328:Adult; D000726:Androgen Antagonists / Q000627:therapeutic use*; D004542:Ejaculation; D005485:Flutamide / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020018:Sexual Dysfunctions, Psychological / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology*; D012803:Sick Role; D013577:Syndrome; D013997:Time Factors
chemical_list: D000726:Androgen Antagonists; D005485:Flutamide