[Controlled liberation of active principles by means of new galenic formulations].
Drugs inside a conventional galenic form are distributed between specific biological targets and other anatomical tissues. With the aim to obtain a more rational and a better therapeutic, one of the most promising possibilities by using the concept of vectorization: association of an active principle to an appropriate vector with the object to increase its action efficiency and efficacy. By this means, they do not just increase the affinity of the drug to the target but also active principle gets protected from a potentially hostile environment (hydrolytic enzymes, acid pH, etc.). The success in the extension of the applications of the vectorización depends more and more of an appropriate design, for what the fundamental objective of this revision will be the one of presenting the general characteristics and some of the current applications in these new galenic forms.
Murillo
M
M
Departamento de Farmacia y Tecnología Farmacéutica, Universidad de Navarra.
Espuelas
S
S
Prior
S
S
Vitas
A I
AI
Renedo
M J
MJ
Goñi
M M
MM
Irache
J M
JM
Gamazo
C
C
D004337:Drug Carriers / Q000627:therapeutic use; D005544:Forecasting; D006801:Humans; D008081:Liposomes; D010316:Particle Size
D004337:Drug Carriers; D008081:Liposomes