title: Factors associated with measles complications in Gweru, Zimbabwe.
abstract: OBJECTIVE
  To investigate factors associated with complications or death among measles cases.
  
  
  METHODS
  A cross-sectional study.
  
  
  METHODS
  Health facilities in the city of Gweru, Zimbabwe.
  
  
  METHODS
  Six hundred and thirty seven measles cases randomly selected from measles surveillance data.
  
  
  METHODS
  (a) Associations of respiratory complications and diarrhoea with death among complicated cases; (b) associations of age at infection, gender of cases and vaccination status of cases with occurrence of either respiratory complications or diarrhoea or death among measles cases.
  
  
  RESULTS
  Among cases with respiratory complications, twenty two (29%) had died, while five (5%) had died among those with diarrhoea (OR=7.06,95% CI=2.55-22.35, p<0.001). On rates of respiratory complications among cases, age groups 24-59 and 60+ months were protective by 57% (95% CI=11-79%) and 76% (95% CI=52-88%) respectively compared to the age group <24 months, and vaccination was protective by 42% (95% CI=2-65%) compared to those unvaccinated. Concerning rates of diarrhoea among cases, the age group 60+ months was protective by 80% (95% CI=62-89%) compared to age group <60 months, while vaccination was protective by 64% (95% CI=42-77%) compared to those unvaccinated. With respect to rates of mortality among cases, age was protective by six per cent (95% CI=3-9 %) for every year older.
  
  
  CONCLUSIONS
  It was concluded that: (a) the risk of death was higher in cases with respiratory complications than diarrhoea; (b) the risk of complications and death was inversely related to age at infection and older age groups were protective against occurrence of complications or death; (c) the risk of complications was higher in unvaccinated cases and vaccination was protective against occurrence of complications.
authors: Department of Community Medicine, University of Zimbabwe Medical School, Avondale, Harare.
authors: T
authors: T
authors: Marufu
authors: S
authors: S
authors: Siziya
authors: M
authors: M
authors: Tshimanga
authors: S
authors: S
authors: Murugasampillay
authors: E
authors: E
authors: Mason
authors: B
authors: B
authors: Manyame
mesh_terms: D000367:Age Factors; D002675:Child, Preschool; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008457:Measles / Q000150:complications* / Q000453:epidemiology; D012141:Respiratory Tract Infections / Q000209:etiology; D012307:Risk Factors; D012737:Sex Factors; D015996:Survival Rate; D015030:Zimbabwe / Q000453:epidemiology