Ion-channel sensing of ferricyanide anion based on a supported bilayer lipid membrane.
Ferricyanide anion has usually been used as a marker of ion-channel sensors. In this work we first found that ferricyanide, itself, can act as a stimulus to regulate the permeability of sBLM prepared from didodecyldimethylammonium bromide (a kind of synthetic lipid) on a GC electrode. We used cyclic voltammetry and a.c. impedance to investigate this phenomenon. The interaction between sBLM and ferricyanide concerns time. Furthermore, we developed a sensor for ferricyanide anion. The ion-channel sensor is highly sensitive. It can detect ferricyanide concentration as low as 5 microM.
Han
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X
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Jilin, People's Republic of China.
Wang
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E
D000838:Anions / Q000737:chemistry; D015374:Biosensing Techniques / Q000379:methods*; D002244:Carbon / Q000737:chemistry; D017097:Electric Impedance; D004566:Electrodes; D005292:Ferricyanides / Q000737:chemistry*; D007473:Ion Channels / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods; D013997:Time Factors
D000838:Anions; D005292:Ferricyanides; D007473:Ion Channels; D008051:Lipid Bilayers; C007931:hexacyanoferrate III; D002244:Carbon