Synthesis of a globotetraose trimer.
The synthesis is described of a globotetraose trimer in 74% yield by the reaction of tris(2-aminoethyl)amine with the hydrophobic squaric decyl ester glycoside of globotetraose. The synthesis was readily monitored and purified using reversed phase HPLC. Unreacted squaric decyl ester globotetraoside was recovered rendering the method highly economical.
Bergh
Anders
A
Organic and Bioorganic Chemistry, Lund University, PO Box 124, SE-221 00 Lund, Sweden.
Bhattacharyya
Sumita
S
Nilsson
Ulf J
UJ
D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D005915:Globosides / Q000138:chemical synthesis*; D008969:Molecular Sequence Data
D005915:Globosides; C035968:globotetraose