title: Effects of quantity and quality of dietary protein on the brain polysome profile in aged rats.
abstract: The purpose of this study was to determine whether the quantity and quality of dietary protein affected the polysome profile of the brain in aged rats. Two experiments were done on three groups of aged rats (30 wk) given the diets containing 20% casein, 5% casein, or 0% casein (experiment 1), and 20% casein, 20% gluten, or 20% gelatin (experiment 2) for 10 d. The aggregation in brain ribosomes declined with a decrease of quantity and quality of dietary protein except in the hippocampus. The RNA concentration (mg RNA/g protein) did not differ among the three groups varying the dietary protein in any brain regions. The results suggest that the higher quantity and quality of dietary protein improves the polysome profile in the brain of aged rats, and that the polysome profile is at least partly related to the mechanism by which the dietary protein affects brain protein synthesis in aged rats.
authors: Department of Home Economics, Aichi University of Education, Kariya, Japan.
authors: Emi
authors: E
authors: Hirano
authors: Sunok
authors: S
authors: Lyou
authors: Kazuyo
authors: K
authors: Tujioka
authors: Miyuki
authors: M
authors: Tanaka
authors: Kazutoshi
authors: K
authors: Hayase
authors: Satoshi
authors: S
authors: Okuyama
authors: Hidehiko
authors: H
authors: Yokogoshi
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000145:classification / Q000592:standards; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism; D011132:Polyribosomes / Q000378:metabolism*; D012313:RNA / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004044:Dietary Proteins; D009419:Nerve Tissue Proteins; D012313:RNA