Synthesis and cytotoxicities of mannose conjugated S-nitroso-N-acetylpenicillamine (SNAP).
A series of mannose conjugated S-nitroso-N-acetylpenicillamines (SNAPs) has been synthesized, and their cytotoxicities were assessed for DU 145 human prostate cancer cells and Hela R cancer cells.
Wu
Xuejun
X
Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
Tang
Xiaoping
X
Xian
Ming
M
Brauschweiger
Paul G
PG
Wang
Peng George
PG
D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008358:Mannose / Q000737:chemistry*; D013058:Mass Spectrometry; D009569:Nitric Oxide / Q000032:analysis; D026423:S-Nitroso-N-Acetylpenicillamine / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D009569:Nitric Oxide; D026423:S-Nitroso-N-Acetylpenicillamine; D008358:Mannose