Pseudophomins A and B, a class of cyclic lipodepsipeptides isolated from a Pseudomonas species.
The crystal structures of pseudophomins A and B, with primary structures beta-hydroxydecanoyl-L-Leu-D-Glu-D-allo-Thr-D-Ile-D-Leu-D-Ser-L-Leu-D-Ser-L-Ile monohydrate, C(55)H(97)N(9)O(16).H(2)O, and beta-hydroxydodecanoyl-L-Leu-D-Glu-D-allo-Thr-D-Ile-D-Leu-D-Ser-L-Leu-D-Ser-L-Ile monohydrate, C(57)H(101)N(9)O(16).H(2)O, new cyclic lipodepsipeptides isolated from Pseudomonas fluorescens strain BRG100, have been solved. The absolute configuration of pseudophomin A has been determined from anomalous dispersion and the stereochemistry of the beta-hydroxy acid group is R.
Quail
J Wilson
JW
Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon, SK, Canada S7N 5C9. quail@sask.usask.ca
Ismail
Nargis
N
Pedras
M Soledade C
MS
Boyetchko
Susan M
SM
D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008074:Lipoproteins / Q000737:chemistry*; D008958:Models, Molecular; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification; D011487:Protein Conformation; D011549:Pseudomonas / Q000737:chemistry*
D008074:Lipoproteins; D009842:Oligopeptides; D010456:Peptides, Cyclic; C460380:pseudophomin A; C460381:pseudophomin B