Distribution of Trypanosoma congolense in infected multimammate rats (Mastomys coucha): light and electron microscopical studies.
In an attempt to determine whether Trypanosoma congolense occurs both within and outside the blood vessels in an infected animal host, multimammate rats (Mastomys coucha) were infected with T. congolense and samples from spleen, lymph nodes, bone marrow, liver, kidney, lungs, brain, heart, intestines, ovaries and testes were collected. The tissue samples were fixed and processed for light and electron microscopical examination. In all the tissues examined, trypanosomes were found only within the lumen of large and small blood vessels, capillaries and sinuses. It is concluded that following entry into the blood circulation after intra-peritoneal infection of M. coucha, T. congolense remains restricted to the bloodstream.
Ojok
L
L
Department of Veterinary Pathology, Faculty of Veterinary Medicine, Makerere University, P.O. Box 7062, Kampala, Uganda. vetpath@infocom.co.ug
Kaeufer-Weiss
I
I
Weiss
E
E
D000818:Animals; D008854:Microscopy, Electron; D009115:Muridae; D051381:Rats; D012376:Rodent Diseases / Q000469:parasitology / Q000473:pathology; D014348:Trypanosoma congolense / Q000254:growth & development* / Q000648:ultrastructure; D014353:Trypanosomiasis, African / Q000097:blood / Q000469:parasitology* / Q000473:pathology