title: Prevalence of hepatitis C virus and hepatitis G virus in patients with non-Hodgkin's lymphoma.
abstract: Hepatitis C virus (HCV) and hepatitis G virus (HGV) belong to the same family of flaviviridea. A causative role of HCV infection in the pathogenesis of non-Hodgkin's lymphoma (NHL) has been discussed widely. Little is known about the possible association between NHL and HGV discovered recently. In this study, anti-HCV and HGV-RNA prevalence were investigated in a group of 70 patients with NHL. The results were compared to a control group of 70 age- and sex-matched healthy subjects. One patient in each group (1.4%) was found to be anti-HCV-positive; the difference was not statistically significant (P > 0.05). Five subjects in the patient group (7.1%) were positive for HGV-RNA, while a single subject was positive in the control group (1.4%); the difference was not statistically significant (P > 0.05). Odds ratios for anti-HCV and HGV-RNA were 1 and 5.30, respectively. Our findings suggest that neither HCV nor HGV are causative or contributing factors in the aetiopathogenesis of NHL.
authors: Atatürk University, Faculty of Medicine, Department of Haematology, Erzurum, Turkey. hkaya@atauni.edu.tr
authors: H
authors: H
authors: Kaya
authors: M F
authors: MF
authors: Polat
authors: F
authors: F
authors: Erdem
authors: M
authors: M
authors: Gündogdu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015897:Comorbidity; D005260:Female; D018178:Flaviviridae Infections / Q000453:epidemiology* / Q000821:virology; D029407:GB virus C / Q000302:isolation & purification* / Q000472:pathogenicity; D016174:Hepacivirus / Q000302:isolation & purification* / Q000472:pathogenicity; D006526:Hepatitis C / Q000453:epidemiology*; D018937:Hepatitis C Antibodies / Q000097:blood; D006525:Hepatitis, Viral, Human / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D008111:Liver Function Tests; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012367:RNA, Viral / Q000097:blood; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology
chemical_list: D018937:Hepatitis C Antibodies; D012367:RNA, Viral