title: Citalopram treatment of minor depression in elderly men: an open pilot study.
abstract: Antidepressant pharmacotherapy in elderly patients is challenging. The authors examined the use of citalopram to treat late-life minor depression. Ten men (mean age: 73+/-2 years) with DSM-IV Minor Depression were administered citalopram 20 mg/day. Efficacy was measured with the Geriatric Depression Scale (GDS), the Montgomery-Asberg Depression Rating Scale (MADRS), and the Clinical Global Impressions of Severity (CGI-S) scales. Citalopram was well tolerated, and GDS, MADRS, and CGI-S scores decreased after 12 weeks. These findings indicate that citalopram is safe and effective in the treatment of late-life minor depression.
authors: Department of Psychiatry, University of Cincinnati College of Medicine, and the Cincinnati VAMC, Cincinnati, OH 45267-0559, USA.
authors: John W
authors: JW
authors: Kasckow
authors: Jeff
authors: J
authors: Welge
authors: Brendan T
authors: BT
authors: Carroll
authors: Arthur
authors: A
authors: Thalassinos
authors: Sonia
authors: S
authors: Mohamed
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D015283:Citalopram / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009820:Ohio; D010044:Outpatient Clinics, Hospital; D010865:Pilot Projects; D011446:Prospective Studies
chemical_list: D018687:Antidepressive Agents, Second-Generation; D015283:Citalopram