title: [Correlation between IL-6 levels and polymerized human serum albumin ceptor (PHSAR) in serum of chronic hepatitis patients].
abstract: BACKGROUND
  To investigate the relationship between interleukin-6 (IL-6) levels in serum and HBV replication and the role of IL-6 in liver damage in chronic hepatitis B patients.
  
  
  METHODS
  Detected IL-6 levels and polymerized human serum albumin receptor (PHSA-R) in serum of different type of HBV markers positive patients and of different degree of chronic hepatitis B patients.
  
  
  RESULTS
  The results showed that the serum IL-6 levels were increased significantly in PHSA-R positive patients than in PHSA-R negative patients in chronic hepatitis B (P<0.01). The serum IL-6 levels were correlated with the levels of PHSA-R (r=0.694, P<0.01), and the degree of symptoms.
  
  
  CONCLUSIONS
  This study suggested that the IL-6 levels in serum of hepatitis B patients correlated HBV replication and the degree of liver damage, serum IL-6 levels may be used as a value indicating of HBV replication, the degree of symptoms and the effect of treatment.
authors: 323rd Hospital of PLA, Xi'an 710054, China.
authors: Zhiqing
authors: Z
authors: Li
authors: Ruiquan
authors: R
authors: Wei
authors: Boquan
authors: B
authors: Jin
mesh_terms: D000328:Adult; D000368:Aged; D006515:Hepatitis B virus / Q000502:physiology; D019694:Hepatitis B, Chronic / Q000097:blood*; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008875:Middle Aged; D017457:Receptors, Albumin / Q000097:blood*; D014779:Virus Replication
chemical_list: D015850:Interleukin-6; D017457:Receptors, Albumin