Spontaneous complex odontoma in a Sprague-Dawley rat.
Complex odontoma from a female Sprague-Dawley rat is described histopathologically. Necropsy revealed a hard (bony), white mass (3.0 x 3.0 x 2.1 cm) on the left mandible. Microscopically, the mass consisted of islands or nests of epithelial and mesenchymal elements that formed abortive tooth structures. In other areas, tooth formation consisted of a pulp cavity lined by layers of odontoblasts, dentin, enamel, and ameloblasts. Concerning all features of normal tooth formation which was differentiated and mineralized yet completely disorganized, the diagnosis of complex odontoma was recommended.
Jang
Dong Deuk
DD
Korea Food and Drug Administration, Department of Pathology, Seoul.
Kim
Chuel-Kyu
CK
Ahn
Byeongwoo
B
Kang
Jin Seok
JS
Nam
Ki Tack
KT
Kim
Dae Joong
DJ
Han
Dong Un
DU
Jung
Kwonil
K
Chung
Han-Kook
HK
Ha
Seung-Kwon
SK
Choi
Changsun
C
Cho
Wan-Seob
WS
Kim
Junghyun
J
Chae
Chanhee
C
D000818:Animals; D005260:Female; D006651:Histocytochemistry / Q000662:veterinary; D008339:Mandibular Neoplasms / Q000473:pathology / Q000662:veterinary*; D009810:Odontoma / Q000473:pathology / Q000662:veterinary*; D051381:Rats; D017207:Rats, Sprague-Dawley