Short-term result of aortic valve replacement with cryopreserved homograft valve in the University of Tokyo Tissue Bank.
The short-term results after aortic root replacement with 11 cryopreserved aortic homografts was examined. Since 1998, the University of Tokyo Tissue Bank has supplied 11 aortic homograft valves. Nine of the recipients were male, and the average age was 51.2 years. Nine out of 11 patients had suffered from a serious condition of native or prosthetic valve infectious endocarditis. All of the patients underwent aortic root replacement, and the blood type between the patient and the homograft was matched in 8 of the patients. Only 1 patient died (9.1%) in the short-term due to sepsis. The preoperative degree of aortic valve regurgitation in all of the cases was third or fourth while the regurgitation disappeared after the operation in all of them. Thinking of the serious condition of our cases preoperatively, the 9.1% operative mortality was quite acceptable. Long-term follow-up is necessary to estimate the quality of the homografts.
Motomura
Noboru
N
Department of Cardiothoracic Surgery, Faculty of Medicine, and University of Tokyo Tissue Bank, University of Tokyo, Tokyo, Japan. n-motomura@umin.ac.jp
Takamoto
Shinichi
S
Murakawa
Tomohiro
T
Yoneda
Noriko
N
Shibusawa
Sakiko
S
Maeda
Katsuhide
K
Suematsu
Yoshihiro
Y
Murakami
Arata
A
Nakajima
Jun
J
Kotsuka
Yutaka
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D015925:Cryopreservation; D004697:Endocarditis, Bacterial / Q000601:surgery*; D005260:Female; D006349:Heart Valve Diseases / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000601:surgery*; D014015:Tissue Banks; D014184:Transplantation, Homologous; D016896:Treatment Outcome