title: Funipuncture for fetocide in late termination of pregnancy.
abstract: The most widely used method for fetocide in late termination of pregnancy for fetal abnormalities (TOPFA) consists of injecting of potassium chloride (KCl) into the fetal heart and is likely to be painful after 22 weeks of gestation. We studied ten consecutive women undergoing TOPFA between 22 and 38 weeks. This technique for fetocide consisted of a single umbilical vein puncture under ultrasound guidance with injections of sufentanil 5 microg followed by KCl 2 g. No electrocardiographic modifications could be observed and maternal plasma potassium levels did not show any significant variation throughout the procedure. Fetal umbilical phlebotomy for fetal analgesia followed by fetocide therefore appears to be a safe procedure for the mother and allows the fetus to die without pain when late termination of pregnancy (TOP) is indicated.
authors: Department of Obstetrics and Gynecology, CHI Poissy, France.
authors: M V
authors: MV
authors: Senat
authors: C
authors: C
authors: Fischer
authors: Y
authors: Y
authors: Ville
mesh_terms: D000015:Abnormalities, Multiple; D000025:Abortion, Eugenic / Q000379:methods*; D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D005260:Female; D005313:Fetal Death / Q000139:chemically induced*; D005333:Fetus / Q000002:abnormalities*; D005865:Gestational Age; D006801:Humans; D007275:Injections, Intravenous; D008431:Maternal-Fetal Exchange; D011189:Potassium Chloride / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000506:poisoning*; D011247:Pregnancy; D017409:Sufentanil / Q000008:administration & dosage / Q000627:therapeutic use; D014471:Umbilical Veins
chemical_list: D000701:Analgesics, Opioid; D011189:Potassium Chloride; D017409:Sufentanil