Relative and absolute stereochemistry of the didemnaketals, metabolites of a Palauan ascidian, Didemnum sp.
[structure: see text] The absolute stereochemistry of the heptaprenoids didemnaketals B (2) and C (3), isolated from a Palauan ascidian, was determined using a combination of degradation and derivatization experiments, chiral shift methods, and comparison of fragments to known compounds.
Salomon
Christine E
CE
Scripps Institution of Oceanography, UCSD, 9500 Gilman Drive, La Jolla 92093-0212, USA.
Williams
David H
DH
Lobkovsky
Emil
E
Clardy
Jon C
JC
Faulkner
D John
DJ
D000818:Animals; D019380:Anti-HIV Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D018360:Crystallography, X-Ray; D004952:Esters / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D015497:HIV-1 / Q000187:drug effects; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D013141:Spiro Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D014561:Urochordata / Q000737:chemistry*
D019380:Anti-HIV Agents; D004952:Esters; D007202:Indicators and Reagents; D013141:Spiro Compounds