Recovery of an unusual fusogenic herpes simplex virus type 2 strain from a clinical specimen.
A highly unusual herpes simplex virus type 2 strain, strain Burr, was isolated from a female genital tract clinical specimen. This virus induced remarkably rapid and extensive syncytium formation in Vero cells involving hundreds of cells but was less fusion active in HEp-2 cells, MRC-5 cells, and mink lung cells. Virus-infected cells produced the glycoproteins gB, gC, gD and gE.
Johnson
F Brent
FB
Department of Microbiology, Brigham Young University, Provo, Utah 84602, USA. brent_johnson@byu.edu
D000818:Animals; D002459:Cell Fusion; D002522:Chlorocebus aethiops; D005260:Female; D015726:Giant Cells / Q000502:physiology; D006558:Herpes Genitalis / Q000175:diagnosis*; D018258:Herpesvirus 2, Human / Q000145:classification / Q000302:isolation & purification*; D006801:Humans; D014709:Vero Cells