title: Antibacterial diterpenoids from Fabiana densa var. ramulosa.
abstract: A biologically monitored fractionation of the resinous exudate of Fabiana densa Remy var. ramulosa Wedd. led to the isolation of the two new diterpenes: ent-beyer-15-en-18-O-succinate and ent-beyer-15-en-18-O-oxalate as the unique compounds responsible for the observed antibacterial activity of this extract. Their structures were determined by 1D and 2D NMR spectroscopy.
authors: Silvia
authors: S
authors: Erazo
authors: Mercedes
authors: M
authors: Zaldívar
authors: Carla
authors: C
authors: Delporte
authors: Nadine
authors: N
authors: Backhouse
authors: Paola
authors: P
authors: Tapia
authors: Eliana
authors: E
authors: Belmonte
authors: Franco
authors: F
authors: Delle Monarche
authors: Rosa
authors: R
authors: Negrete
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D010070:Oxalates / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D019657:Solanaceae; D013386:Succinates / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D004224:Diterpenes; D010070:Oxalates; D010936:Plant Extracts; D013386:Succinates; C459630:ent-beyer-15-en-18-O-oxalate; C459629:ent-beyer-15-en-18-O-succinate