title: NF-kappaB in cancer: from innocent bystander to major culprit.
abstract: Nuclear factor of kappaB (NF-kappaB) is a sequence-specific transcription factor that is known to be involved in the inflammatory and innate immune responses. Although the importance of NF-KB in immunity is undisputed, recent evidence indicates that NF-kappaB and the signalling pathways that are involved in its activation are also important for tumour development. NF-kappaB should therefore receive as much attention from cancer researchers as it has already from immunologists.
authors: Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla 92093, USA. karinoffice@ucsd.edu
authors: Michael
authors: M
authors: Karin
authors: Yixue
authors: Y
authors: Cao
authors: Florian R
authors: FR
authors: Greten
authors: Zhi-Wei
authors: ZW
authors: Li
mesh_terms: D000818:Animals; D006801:Humans; D008206:Lymphatic Diseases / Q000378:metabolism; D008954:Models, Biological; D016328:NF-kappa B / Q000096:biosynthesis*; D009369:Neoplasms / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D016328:NF-kappa B