title: Acute autoimmune cardiomyopathy in primary antiphospholipid antibody syndrome.
abstract: We present a case of acute pulmonary oedema as the first presentation of autoimmune cardiomyopathy in primary antiphospholipid antibody syndrome in a patient who had no previous cardiac history. Five days of methylprednisolone at 500 mg/day followed by 100 mg/day for 10 days and then a weaning course of oral prednisone resulted in effective resolution of the acute diffuse cardiomyopathy. Her cardiac status became clinically and echocardiographically normal. We illustrate the effectiveness of immunosuppressive therapy as an adjunct to standard anti-failure measures in such presentations and we outline the association between antiphospholipid antibodies and cardiac dysfunction.
authors: Intensive Care Unit, St Vincent's Hospital, Melbourne, Victoria.
authors: R
authors: R
authors: Nagappan
authors: R S
authors: RS
authors: Lodge
mesh_terms: D000208:Acute Disease; D016736:Antiphospholipid Syndrome / Q000150:complications*; D009202:Cardiomyopathies / Q000150:complications* / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011654:Pulmonary Edema / Q000150:complications