New developments in childhood celiac disease.
Celiac disease (CD) is one of the most common lifelong disorders in Europe and the United States, in both children and adults. It is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. This review addresses new developments in CD with respect to pediatric patients and emphasizes the need for awareness among health-care professionals. The epidemiology, pathophysiology, diagnosis, and clinical spectrum of CD in children are highlighted.
Catassi
Carlo
C
Center for Celiac Research, Division of Pediatric Gastroenterology and Nutrition, University of Maryland School of Medicine, 685 West Baltimore Street, HSF Building, Room 465, Baltimore, MD 21201, USA.
Fasano
Alessio
A
D000465:Algorithms; D002446:Celiac Disease / Q000175:diagnosis* / Q000276:immunology / Q000503:physiopathology; D002648:Child; D006801:Humans; D007413:Intestinal Mucosa / Q000276:immunology / Q000473:pathology