title: Modulation of insulin signaling in human skeletal muscle in response to exercise.
abstract: Exercise is widely recommended for the treatment of obesity, insulin resistance, and type II diabetes mellitus. Recent discoveries in the molecular and cellular regulation of insulin-mediated glucose metabolism in skeletal muscle have provided a deeper understanding of how exercise modulates insulin action.
authors: Department of Reproductive Biology, Case Western Reserve University School of Medicine at MetroHealth Medical Center, Cleveland, Ohio 44109-1998, USA. jpk10@po.cwru.edu
authors: John P
authors: JP
authors: Kirwan
authors: Ming
authors: M
authors: Jing
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D015444:Exercise / Q000502:physiology*; D006006:Glycogen Synthase / Q000502:physiology; D006801:Humans; D007328:Insulin / Q000502:physiology*; D007333:Insulin Resistance / Q000502:physiology; D018482:Muscle, Skeletal / Q000378:metabolism*; D019869:Phosphatidylinositol 3-Kinases / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D007328:Insulin; D006006:Glycogen Synthase; D019869:Phosphatidylinositol 3-Kinases