The associations of viral and mycoplasmal antibody titers with respiratory disease and weight gain in feedlot calves.
Blood samples from 32 groups of calves (n = 700) were taken on arrival and after 28-35 days at the feedlot. Eleven groups were housed in feedlots in Ontario, and 21 groups in feedlots in Alberta. Serum antibody titers to bovine viral diarrhea virus (BVDV), bovine respiratory syncytial virus (BRSV), parainfluenza virus type 3 (PIV-3), infectious bovine rhinotracheitis virus (IBRV), Mycoplasma dispar and M. bovis, plus data on bovine corona virus (BCV) from a previous study were investigated for their association with the risk of bovine respiratory disease (BRD), and with 28-day weight change, both before and after controlling for titers to Pasteurella haemolytica and Haemophilus somnus. Exposure to IBRV and M. bovis was infrequent, and although exposure to PIV-3 was more common, none of these agents had important associations with BRD. Higher titers to BVDV, BRSV, and BCV on arrival were associated with reduced risks of BRD and increased weight gains. However, there was some variation in these relationships and higher arrival titers to BVDV and BRSV in a subset of the calves were associated with increased risks of BRD. Titer increases to BVDV were associated with a higher risk of BRD and lower weight gains. Titer increases to BRSV were not usually associated with the occurrence of BRD, but titer increases to BRSV in a subset of calves that were vaccinated against BRSV, on arrival, were associated with an elevated risk of BRD. Of all the agents studied, BVDV had the most consistent associations with elevated risk of BRD and lower weight gains. Higher BRSV arrival titers were related to lower risk of BRD and higher weight gains; in some instances titer increases to BRSV were associated with higher BRD risk. Higher titers to BCV on arrival were related to reduced risks of BRD. Practical ways of adequately preventing the negative effects of these agents are still needed.
Martin
S W
SW
Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario.
Nagy
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E
Armstrong
D
D
Rosendal
S
S
D000818:Animals; D000831:Animals, Newborn; D000907:Antibodies, Bacterial / Q000032:analysis* / Q000276:immunology; D000914:Antibodies, Viral / Q000032:analysis* / Q000276:immunology; D016022:Case-Control Studies; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000382:microbiology* / Q000821:virology; D009175:Mycoplasma Infections / Q000276:immunology / Q000662:veterinary; D012140:Respiratory Tract Diseases / Q000276:immunology / Q000382:microbiology / Q000662:veterinary* / Q000821:virology; D015430:Weight Gain
D000907:Antibodies, Bacterial; D000914:Antibodies, Viral