title: [Cytological history of 148 women presenting with invasive cervical cancer].
abstract: OBJECTIVE
  The aim of this study was to analyse the cytological history of women presenting with invasive cervical cancer.
  
  
  METHODS
  Retrospective study of 148 patients treated for invasive cervical cancer in three hospitals of the North Pas de Calais in France.
  
  
  RESULTS
  The average age of patients was 49 (26-86). Squamous carcinomas represented 81% of cases (120/148), adenocarcinomas 17% (25/148) and adenosquamous carcinomas 2% (3/148). 36.5% of patients (54/148) had never had a Pap smear. 34.5% (51/148) had had an occasional Pap smear (the last one dated of more than three years). 8.1% (12/148) were lost for follow up after a positive Pap smear. 3.4% (5/148) were treated for cervical dysplasia less than three years before the diagnosis of the cervical cancer. 17.5% (26/148) had had a Pap smear reported as negative less than three years before the diagnosis of the cervical cancer. In this last group, squamous carcinomas represented 57.7% of cases (15/26), adenocarcinomas 38.5% (10/26) and adenosquamous carcinomas 3.8% (1/26). 18 Pap smears of 26 reported as negative less than three years before the diagnosis of the cancer were reviewed. These Pap smears came from 11 patients presenting with squamous carcinoma and seven other presenting with adenocarcinoma. After review, 15 Pap smears were reported as false negatives and two as true negatives. The review was not possible in one case.
  
  
  CONCLUSIONS
  In this study, the failures of cervical cancer screening were essentially attributed to the lack or the insufficiency of screening and the existence of false negatives of the cytology.
authors: Clinique de gynécologie-obstétrique et néonatologie, hôpital Jeanne-de-Flandre, CHRU de Lille, 59037 Lille, France. ndaye@club-internet.fr
authors: N
authors: N
authors: Mubiayi
authors: E
authors: E
authors: Bogaert
authors: F
authors: F
authors: Boman
authors: E
authors: E
authors: Leblanc
authors: D
authors: D
authors: Vinatier
authors: J L
authors: JL
authors: Leroy
authors: D
authors: D
authors: Querleu
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018196:Carcinoma, Adenosquamous / Q000175:diagnosis* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000592:standards / Q000706:statistics & numerical data; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D065006:Papanicolaou Test; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014626:Vaginal Smears / Q000706:statistics & numerical data