Synthesis and hybridization studies of a 5-aminopentanoic acid nucleobase (APN) dimer.
We have prepared a 5-aminopentanoic acid nucleobase (APN) dimer and investigated its hybridization capabilities to complementary DNA using both UV melting and NMR techniques.
Donaldson
Susan F
SF
Division of Medicinal Chemistry, Ohio State University, Columbus 43210, USA.
Bergmeier
Stephen C
SC
Hines
Jennifer V
JV
Gerdeman
Melinda S
MS
D021542:Amino Acids, Neutral / Q000096:biosynthesis* / Q000737:chemistry / Q000378:metabolism; D018076:DNA, Complementary / Q000378:metabolism; D019281:Dimerization; D009682:Magnetic Resonance Spectroscopy; D009693:Nucleic Acid Hybridization; D014466:Ultraviolet Rays
D021542:Amino Acids, Neutral; D018076:DNA, Complementary; C013809:5-aminovaleric acid