title: Signal-averaged electrocardiographic parameter progression as a marker of increased electrical instability in two cases with an overt form of arrhythmogenic right ventricular cardiomyopathy.
abstract: In arrhythmogenic right ventricular cardiomyopathy (ARVC) the fibrofatty substitution of the RV myocardium constitutes the substrate for reentrant circuits, leading to the onset of ventricular arrhythmias. This pathological process also accounts for "delayed ventricular potentials" that could be recorded as late potentials using the signal-averaged ECG technique (SAECG). This study examined two patients affected by overt forms of ARVC who showed a worsening of the electrical instability associated with a fast progression of SAECG parameters, while all the other clinical findings remained unchanged. This suggests a possible role of SAECG parameter progression as a marker of increased electrical instability.
authors: Department of Cardiology, University of Padua Medical School, Italy.
authors: Barbara
authors: B
authors: Bauce
authors: Cristina
authors: C
authors: Basso
authors: Andrea
authors: A
authors: Nava
mesh_terms: D000293:Adolescent; D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D017180:Tachycardia, Ventricular / Q000209:etiology*