Microsatellite characterization of Plasmodium falciparum from cerebral and uncomplicated malaria patients in southern Vietnam.
If parasite genotype influences the clinical course of malaria, we expect that isolates from patients with similar pathology would be more closely related than would be expected by chance. To explore this prediction, we typed nine microsatellite markers in sympatric Plasmodium falciparum isolates from cerebral and uncomplicated malaria patients from Vietnam. Temporal structure and linkage disequilibrium were also examined in this data set.
Ferreira
Marcelo U
MU
Department of Parasitology, Institute for Biomedical Sciences, University of São Paulo, Av. Prof. lineu Prestes 1374, 05508-900 São Paulo (SP), Brazil. muferrei@usp.br
Nair
Shalini
S
Hyunh
Thien Van
TV
Kawamoto
Fumihiko
F
Anderson
Timothy J C
TJ
D000818:Animals; D002874:Chromosome Mapping; D006801:Humans; D015810:Linkage Disequilibrium; D016779:Malaria, Cerebral / Q000175:diagnosis*; D016778:Malaria, Falciparum / Q000175:diagnosis*; D018895:Microsatellite Repeats; D010802:Phylogeny; D010963:Plasmodium falciparum / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D014744:Vietnam