title: Olanzapine associated weight gain, hyperglycemia and neuroleptic malignant syndrome: case report.
abstract: We describe here a case of olanzapine associated weight gain, hyperglycemia and neuroleptic malignant syndrome in a 64 year-old woman with a significant medical history. Eighteen weeks after initiating olanzapine, Mrs X lost glycemic control, exhibited signs and symptoms consistent with neuroleptic malignant syndrome and gained 8.9 kg. We suggest that utilization of olanzapine in the less medically stable geriatric patient be implemented with vigilant monitoring for such complications mentioned above.
authors: Department of Pharmacy, Riverview Hospital, Port Coquitlam, BC, Canada.
authors: Rhonda
authors: R
authors: Malyuk
authors: Bruce
authors: B
authors: Gibson
authors: Ric M
authors: RM
authors: Procyshyn
authors: Nirmal
authors: N
authors: Kang
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000139:chemically induced*; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*; D000077152:Olanzapine; D010890:Pirenzepine / Q000009:adverse effects* / Q000031:analogs & derivatives*; D015430:Weight Gain
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine