A rare form of hypothyroidism.
Secondary hypothyroidism is extremely rare. In the majority of cases, there is a genetic (gene mutations) or structural (mass effect or infiltration) basis for central hypothyroidism, and there is simultaneous deficiency of other adenohypophysial hormones. Isolated deficiency of thyrotropin is even rarer. This report features the case of a woman who had isolated thyrotropin deficiency, with the remainder of the anterior pituitary hormones being normal. The various causes of central hypothyroidism and the role of the thyrotropin-releasing hormone test are briefly described.
Basaria
Shehzad
S
Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
Braga
Milena
M
D016903:Drug Monitoring; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000172:deficiency*; D013973:Thyrotropin-Releasing Hormone / Q000502:physiology; D013974:Thyroxine / Q000008:administration & dosage
D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin; D013974:Thyroxine