title: Genotoxicological effects of some phenoxyherbicides and their metabolites on Bacillus subtilis M45 Rec- and H17 Rec+ strains.
abstract: Because they are used in a number of commercial preparations phenoxyacetic acids and their salts can occur in wastewater. During their degradation genotoxic substances may be created. The results of investigations of biodegradability and genotoxicity of some phenoxyherbicides are presented. Commercial formulations of 2,4-D (Aminopielik 720) and MCPA (Chwastox Extra) were the substrates studied. Biodegradation tests were conducted according to OECD guidelines for testing of chemicals--confirmatory test (OECD Method 303 A). Genotoxicity tests were conducted with Bacillus subtilis strains according to the method of [Chemical Mutagens, vol. 6, Plenum Press. New York, 1980, p. 149]. Genotoxicity of biodegradation products was also studied. Both commercial formulations were biodegradable. Aminopielik 720 was potentially genotoxic but only at great concentrations while Chwastox Extra was not genotoxic. Biodegradation products of neither compound were genotoxic.
authors: Department of Environmental Biotechnology, Technical University of Silesia, Gliwice, Poland.
authors: Elzbieta
authors: E
authors: Grabińska-Sota
authors: Ewa
authors: E
authors: Wiśniowska
authors: Joanna
authors: J
authors: Kalka
authors: Beata
authors: B
authors: Scieranka
mesh_terms: D000085:Acetates / Q000009:adverse effects* / Q000378:metabolism; D001412:Bacillus subtilis / Q000235:genetics*; D001673:Biodegradation, Environmental; D006540:Herbicides / Q000009:adverse effects* / Q000378:metabolism; D009152:Mutagenicity Tests; D014874:Water Pollutants, Chemical / Q000009:adverse effects* / Q000378:metabolism
chemical_list: D000085:Acetates; D006540:Herbicides; D014874:Water Pollutants, Chemical; C415326:phenoxyacetic acid