title: Molecular cloning of three nonhuman primate follicle stimulating hormone beta-subunit cDNAs.
abstract: The follicle stimulating hormone (FSH) beta-subunit cDNAs were cloned and sequenced for an old world primate, the rhesus monkey (Macaca mulatta), and two New World primates, the common marmoset (Callithrix jacchus) and pygmy marmoset (Cebuella pygmaea). The cDNA and predicted amino acid sequences of the rhesus monkey FSH beta-subunit were related most closely to the human FSH beta-subunit (> 96% identity). The common and pygmy marmosets have identical FSH beta-subunit cDNAs, whereas the marmoset FSH beta-subunit diverges from the rhesus and human molecules with less than 93% identity. These results have significance for the implementation of assisted reproductive technologies in the nonhuman primate as well as the evolution of genes encoding reproductive hormones.
authors: Wisconsin Regional Primate Research Center, University of Wisconsin, Madison 53715-1299, USA.
authors: M J
authors: MJ
authors: Wolfgang
authors: R L
authors: RL
authors: Grendell
authors: T G
authors: TG
authors: Golos
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002144:Callithrix / Q000235:genetics*; D002143:Callitrichinae / Q000235:genetics*; D002417:Cattle; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D005640:Follicle Stimulating Hormone / Q000737:chemistry / Q000235:genetics*; D037201:Follicle Stimulating Hormone, beta Subunit; D006801:Humans; D008253:Macaca mulatta / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data; D021122:Protein Subunits; D012756:Sheep
chemical_list: D018076:DNA, Complementary; D037201:Follicle Stimulating Hormone, beta Subunit; D021122:Protein Subunits; D005640:Follicle Stimulating Hormone