title: Contrast-enhanced high in-plane resolution dynamic MRI of the breast. Are there advantages in comparison to standard dynamic MRI?
abstract: OBJECTIVE
  To evaluate the diagnostic advantages of high in-plane resolution contrast-enhanced (CE) magnetic resonance imaging (MRI) of the breast in comparison to standard CE-MRI.
  
  
  METHODS
  Forty-one patients with 51 hypervascularized lesions were selected prospectively after undergoing bilateral standard CE MRI (slice thickness 4 mm, in-plane resolution 1.52 x 1.25 mm2, temporal resolution 81 s). Patients underwent high in-plane resolution CE MRI, either (n=21) a two-dimensional fast-low-angle-shot sequence (slice thickness 4 mm, in-plane resolution 0.76 x 0.63 mm2, temporal resolution 96 s) or (n=20) a SE sequence being used (slice thickness 4 mm, in-plane resolution 0.8 x 0.63 mm2, temporal resolution 115 s).
  
  
  RESULTS
  Histopathology revealed 33 malignant and 18 benign lesions (0.2-2.2 cm). Morphologic characteristics were much better visualized with high in-plane resolution. Additional diagnostic information, however, resulted only in one patient with fibroadenoma due to a better visualization of smooth contours.
  
  
  CONCLUSIONS
  High in-plane resolution provides better visualization of morphologic patterns in comparison to standard dynamic MRI. However, a diagnostic advantage is only rare.
authors: Department of Radiology, Georg-August-University of Göttingen, Robert-Koch-Strasse 40, Germany. soben@med.uni-göttingen.de
authors: Silvia
authors: S
authors: Obenauer
authors: Corinna
authors: C
authors: Schorn
authors: Bruno
authors: B
authors: Stelter
authors: Uwe
authors: U
authors: Fischer
authors: Eckhardt
authors: E
authors: Grabbe
mesh_terms: D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*
chemical_list: D003287:Contrast Media