title: Volume estimation of excimer laser tissue ablation for correction of spherical myopia and hyperopia.
abstract: OBJECTIVE
  To determine the theoretical volumes of ablation for the laser treatment of spherical refractive errors in myopia and hyperopia.
  
  
  METHODS
  The cornea was modeled as a spherical shell. The ablation profiles for myopia and hyperopia were based on an established paraxial formula. The theoretical volumes of the ablated corneal lenticules for the correction of myopia and hyperopia were calculated by two methods: (1) mathematical approximation based on a simplified geometric model and (2) finite integration. These results were then compared for optical zone diameters of 0.5 to 11.00 mm and for initial radii of curvature of 7.5, 7.8, and 8.1 mm.
  
  
  RESULTS
  Referring to a simplified geometrical model, the volume of ablated corneal tissue was estimated to be proportional to the magnitude of treatment (D) and to the fourth power of the treatment diameter (S(4)). For refractive correction of myopia and hyperopia, volume estimations using our formula, V congruent with D. (S/9)(4), were similar to those obtained by finite integration for optical zone diameters of 0.5 to 8.5 mm and for corneal radii of curvature within the clinical range (7.5, 7.8, and 8.1 mm).
  
  
  CONCLUSIONS
  The theoretical volume of corneal tissue ablated within the optical zone for spherical corrections can be accurately approximated by this simplified formula. This may be helpful in evaluating factors that contribute to corneal ectasia after LASIK for myopia and hyperopia. Treatment diameter (S) is the most important determinant of the volume of tissue ablation during excimer laser surgery.
authors: Rothschild Foundation, Paris, France.
authors: Damien
authors: D
authors: Gatinel
authors: Thanh
authors: T
authors: Hoang-Xuan
authors: Dimitri T
authors: DT
authors: Azar
mesh_terms: D048429:Cell Size; D003315:Cornea / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D006956:Hyperopia / Q000473:pathology / Q000601:surgery*; D020731:Keratomileusis, Laser In Situ; D008433:Mathematics; D008962:Models, Theoretical; D009216:Myopia / Q000473:pathology / Q000601:surgery*