title: Long-term results of laparoscopic antireflux surgery.
abstract: BACKGROUND
  It is estimated that laparoscopic antireflux surgery has replaced the open approach in centers worldwide. Findings show it to be an established treatment option for chronic gastroesophageal reflux disease with an excellent clinical outcome and success rates between 85% and 95%. This prospective study aimed to evaluate surgical outcome and analysis of failure after 500 laparoscopic antireflux procedures followed up for as long as 5 years.
  
  
  METHODS
  Between September 1993 and May 2000, 500 laparoscopic antireflux procedures were performed in our surgical unit. In 345 patients, a laparoscopic "floppy" Nissen fundoplication was performed, and in 155 patients, a Toupet fundoplication was carried out with standard mobilization of the upper part of the gastric fundus and with division of the short gastric vessels. Preoperative and postoperative data including 24-h pH monitoring, esophageal manometry, and analysis of failure were prospectively reviewed.
  
  
  RESULTS
  Conversion to open surgery was necessary in two patients (0.4%). Morbidity was 7%, including 24 patients (4.8%) for whom a laparoscopic redoprocedure was necessary because of failed primary intervention. There was no mortality. During a follow-up period of 3 months to 5 years, 24-h pH monitoring and esophageal manometry showed normal values in 95% of the patients including patients who had undergone redosurgery.
  
  
  CONCLUSIONS
  The results of the current study demonstrate that laparoscopic antireflux surgery is feasible and effective, and that it can be performed safely without mortality and with low morbidity, yielding good to excellent results over a follow-up period up to 5 years.
authors: Department of General Surgery, Hospital Zell am See, A-5700 Zell am See, Austria. FAGZELLAMSEE@yahoo.com
authors: F A
authors: FA
authors: Granderath
authors: T
authors: T
authors: Kamolz
authors: U M
authors: UM
authors: Schweiger
authors: M
authors: M
authors: Pasiut
authors: C F
authors: CF
authors: Haas
authors: H
authors: H
authors: Wykypiel
authors: R
authors: R
authors: Pointner
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication / Q000379:methods / Q000706:statistics & numerical data; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011446:Prospective Studies; D012086:Reoperation / Q000379:methods / Q000706:statistics & numerical data; D016896:Treatment Outcome