title: The molecular and supramolecular structures of four 1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazolines.
abstract: The supramolecular structures of the title compounds, 2-phenyl-5-p-tolyl-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(23)H(21)N(3), (I), 5-(4-bromophenyl)-2-phenyl-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(22)H(18)BrN(3), (II), 2-(4-chlorophenyl)-5-phenyl-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(22)H(18)ClN(3), (III), and 5-(4-bromophenyl)-2-(4-chlorophenyl)-1,5,6,10b-tetrahydropyrazolo[1,5-c]quinazoline, C(22)H(17)BrClN(3), (IV), are of two general types. Compounds (I), (II) and (III) form base-paired dimers via N-H.N hydrogen bonds, where (I) and (II) are isomorphous, while in (IV), there are no conventional hydrogen bonds.
authors: Department of Chemistry, University of Aberdeen, Meston Walk, Old Aberdeen AB24 3UE, Scotland. jnlow111@hotmail.com
authors: John Nicolson
authors: JN
authors: Low
authors: Justo
authors: J
authors: Cobo
authors: Manuel
authors: M
authors: Nogueras
authors: Adolfo
authors: A
authors: Sánchez
authors: Harlen
authors: H
authors: Torres
authors: Braulio
authors: B
authors: Insuasty
mesh_terms: D000596:Amino Acids / Q000037:antagonists & inhibitors; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry; D018360:Crystallography, X-Ray; D019281:Dimerization; D007166:Immunosuppressive Agents / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D011799:Quinazolines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D011720:Pyrazoles; D011799:Quinazolines