Effects of small peptides or amino acids infused to a perfused area of the skin of Angora goats on mohair growth.
The effect of infusing dipeptides or their amino acids on mohair growth of Angora goats was investigated using a skin perfusion technique. Seven Angora wethers (average BW 24 +/- 2.5 kg) were implanted bilaterally with silicon catheters into the superficial branches of the deep circumflex iliac artery and vein and carotid artery. The experiment consisted of three 28-d phases. In the first 14 d of Phases 1 and 3, saline was infused into deep circumflex iliac arteries supplying skin and in Phase 2 a mixture of dipeptides (methionine-leucine [Met-Leu], lysine-leucine [Lys-Leu]) was infused into the artery on one side, and free amino acids were administered on the other side. Infusion rates of peptides were 0.85 mg/h Met-Leu and 0.85 mg/h Lys-Leu in 2.4 mL saline. Infusion rates of amino acids were 0.474 mg/h Lys, 0.483 mg/h Met, and 0.743 mg/h Leu in 2.4 mL saline. A 100-cm2 area within the perfused region was used to determine mohair growth. Two weeks after the cessation of infusions, perfused areas were shorn. Clean mohair production from the dipeptide- and amino acids-perfused regions were similar (4.21 vs 4.35 g/[100 cm2 +/- 28 d], respectively; P > 0.05). However, clean mohair production during dipeptides and amino acids infusions was greater (P < 0.01) than that observed during saline infusions (3.63 g/[100 cm2 +/- 28 d]). There were no significant differences between dipeptides and free amino acids in concentrations of various hormones and metabolites in blood from deep circumflex iliac veins (P > 0.05). In conclusion, the studied small dipeptides and amino acids similarly increased mohair fiber growth, presumably through supplying limiting amino acids directly to the fiber follicle.
Puchala
R
R
E (Kika) de la Garza Institute for Goat Research, Langston University, OK 73050, USA. rpuchala@yahoo.com
Pierzynowski
S G
SG
Wuliji
T
T
Goetsch
A L
AL
Sahlu
T
T
Lachica
M
M
Soto-Navarro
S A
SA
D000596:Amino Acids / Q000008:administration & dosage* / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D004151:Dipeptides / Q000008:administration & dosage* / Q000378:metabolism / Q000494:pharmacology; D006041:Goats / Q000502:physiology*; D006197:Hair / Q000187:drug effects / Q000254:growth & development*; D007930:Leucine / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology; D008239:Lysine / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology; D008297:Male; D008715:Methionine / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology; D010477:Perfusion / Q000379:methods / Q000662:veterinary; D012867:Skin / Q000098:blood supply / Q000378:metabolism
D000596:Amino Acids; D004151:Dipeptides; D008715:Methionine; D007930:Leucine; D008239:Lysine