title: Aortic arch advancement: the optimal one-stage approach for surgical management of neonatal coarctation with arch hypoplasia.
abstract: BACKGROUND
  The optimal surgical treatment for neonatal coarctation with aortic arch hypoplasia (NCoAo/AAH) is controversial. Important long-term concerns include arch growth. We report our results obtained with a one-stage radical approach of coarctectomy and aortic arch advancement for NCoAo/AAH.
  
  
  METHODS
  From June 1995 to December 2000, 65 newborns with NcoAo/AAH underwent coarctectomy and aortic arch advancement via a median sternotomy under deep hypothermic circulatory arrest. Patients were classified by diagnosis: group 1, isolated NCoAo/AAH (n = 13); group 2, NCoAo/AAH with ventricular septal defect (n = 20); and group 3, NCoAo/AAH with complex cardiac lesions (n = 32).
  
  
  RESULTS
  The study population included 36 boys and 29 girls. Mean age was 13 +/- 1.7 days (range 1 to 43 days). Mild to moderate left ventricular outflow tract obstruction was present in 15 patients. Mean body weight was 3.4 +/- 0.1 kg (range 1.6 to 5 kg). Eight babies were premature. The mean Z value for the aortic arch was -4 +/- 0.3 (range -2 to -4.5) and for the isthmus -4.5 +/- 0.2 (range -3 to -7). Mean deep hypothermic circulatory arrest time was 28 +/- 2 minutes (range 14 to 60 minutes). Mean intensive care unit stay was 6 +/- 1 days (range 2 to 30 days). There were three early deaths (all in groups 2 and 3) and two late deaths (in group 3) (5-year actuarial survival, 91% +/- 7.9%). There was one recurrence (5-year actuarial freedom from recurrence, 98% +/- 4%). Peak Doppler velocity across the arch in the remaining patients was 1 +/- 0.1 m/s (range 0 to 2.2 m/s).
  
  
  CONCLUSIONS
  Coarctectomy and aortic arch advancement is the optimal surgical method for management of NCoAo/AAH. It has low operative morbidity and mortality and a very low incidence of recoarctation or arch obstruction.
authors: Congenital Heart Surgery Service, Texas Children's Hospital, and Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston 77030-2399, USA.
authors: Mohamed-Adel
authors: MA
authors: Elgamal
authors: E Dean
authors: ED
authors: McKenzie
authors: Charles D
authors: CD
authors: Fraser
mesh_terms: D001013:Aorta, Thoracic / Q000002:abnormalities* / Q000601:surgery*; D001017:Aortic Coarctation / Q000150:complications / Q000601:surgery*; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications / Q000401:mortality; D012008:Recurrence