title: Information processing in bacterial chemotaxis.
abstract: Motile bacteria respond to attractants and repellents in their environment by changing their movement. Stock et al. describe the similarities of the bacterial chemotaxis signaling system to eukaryotic signaling cascades. Also included is a discussion of how the ordered signaling complex of the receptor, the kinase CheA, and the kinase regulator CheW can be thought of as a primitive "probrain" to allow the integration of signals to produce the optimal cellular response.
authors: Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. jstock@princeton.edu
authors: Jeffry B
authors: JB
authors: Stock
authors: Mikhail N
authors: MN
authors: Levit
authors: Peter M
authors: PM
authors: Wolanin
mesh_terms: D000818:Animals; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D002633:Chemotaxis / Q000502:physiology*; D004926:Escherichia coli / Q000502:physiology; D029968:Escherichia coli Proteins; D000071677:Histidine Kinase; D008565:Membrane Proteins / Q000502:physiology; D000072236:Methyl-Accepting Chemotaxis Proteins; D015398:Signal Transduction / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins; D000071677:Histidine Kinase; C000607608:cheA protein, E coli