Measurement of breast density with dual X-ray absorptiometry: feasibility.
Dual x-ray absorptiometry (DXA) was used to quantify breast density with a phantom and with cadaveric breasts. With DXA, percentage of fat correlated with percentage of glandular density of the phantom (r > 0.998) and with density at mammography (r(adjusted) = 0.83). DXA precision (SD) was 0.5% without and 1.1% with breast repositioning. DXA devices can be used to accurately and precisely estimate breast tissue density.
Shepherd
John A
JA
Department of Radiology, Osteoporosis and Arthritis Research Group, University of California at San Francisco, 94143, USA. john.shepherd@oarg.ucsf.edu
Kerlikowske
Karla M
KM
Smith-Bindman
Rebecca
R
Genant
Harry K
HK
Cummings
Steve R
SR
D015502:Absorptiometry, Photon / Q000295:instrumentation*; D000273:Adipose Tissue / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D001940:Breast / Q000033:anatomy & histology*; D002102:Cadaver; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D019047:Phantoms, Imaging; D012044:Regression Analysis