title: Staple-line ulcer in the ileal reservoir following restorative proctocolectomy.
abstract: OBJECTIVE
  Following restorative proctocolectomy, seven cases with staple line ulcer around the pouch anal anastomosis and/or staple line in the ileal pouch were experienced. Their clinical, endoscopical characteristics were analyzed.
  
  
  METHODS
  The patients noted anal bleeding following restorative proctocolectomy were examined with colonofiberscopy and histological study was conducted.
  
  
  RESULTS
  Staple line ulcer was seens in seven cases (2.3%, 7/304). The onset was immediate or within 2 months postoperatively in 5 cases. Bleeding occurred in all the patients and lower abdominal pain, anal pain, increased bowel movements and anal fissure were seen frequently. Ulcers were linear along the staple line and there were no cases complicated by simultaneous pouchitis. Most of the patients responded to treatments with metronidazol, 5-ASA, and topical or oral steroids, although one patient required ligation of bleeding ulcer and two complicated perianal excoriation required ileostomy.
  
  
  CONCLUSIONS
  Staple line ulcer should be recognized as different complication to pouchitis.
authors: Department of Surgery, Yokohama City Hospital, Yokohama, Japan.
authors: Tsuneo
authors: T
authors: Fukushima
authors: Akira
authors: A
authors: Sugita
authors: Kazutaka
authors: K
authors: Koganei
authors: Shoichi
authors: S
authors: Fujii
authors: Masaru
authors: M
authors: Shinozaki
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000601:surgery; D000328:Adult; D003093:Colitis, Ulcerative / Q000601:surgery; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016737:Proctocolectomy, Restorative / Q000009:adverse effects* / Q000379:methods; D017792:Surgical Stapling / Q000009:adverse effects*; D014456:Ulcer / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology