title: Dynamic localization of proteins and DNA during a bacterial cell cycle.
abstract: A cellular differentiation programme that culminates in an asymmetric cell division is an integral part of the cell cycle in the bacterium Caulobacter crescentus. Recent work has uncovered mechanisms that ensure the execution of many events at different times during the cell cycle and at specific places in the cell. Surprisingly, in this one-micron bacterial cell, the dynamic spatial disposition of regulatory proteins, structural proteins and specific regions of the chromosome are important components of both cell-cycle progression and the generation of daughter cells with different cell fates.
authors: Genencor International Inc., 925 Page Mill Road, Palo Alto, California 94304-1013, USA.
authors: Rasmus B
authors: RB
authors: Jensen
authors: Sherry C
authors: SC
authors: Wang
authors: Lucy
authors: L
authors: Shapiro
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D016935:Caulobacter crescentus / Q000166:cytology* / Q000235:genetics / Q000378:metabolism*; D002453:Cell Cycle; D002455:Cell Division; D002876:Chromosomes, Bacterial; D004269:DNA, Bacterial / Q000378:metabolism*; D004268:DNA-Binding Proteins; D008954:Models, Biological; D015398:Signal Transduction; D014157:Transcription Factors
chemical_list: D001426:Bacterial Proteins; C097706:CtrA protein, Caulobacter; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins; D014157:Transcription Factors