Isoniazid-induced seizures with secondary rhabdomyolysis and associated acute renal failure in a dog.
Isoniazid-induced seizures resulted in rhabdomyolysis and associated acute renal tubular necrosis in a dog. Rhabdomyolysis and myoglobinuric renal failure, although recognised in the dog, are reported infrequently as a consequence of seizures. The clinical presentation of isoniazid toxicity in a dog is described.
Haburjak
J J
JJ
Ocean Avenue Veterinary Hospital, San Francisco, CA 94112, USA.
Spangler
W L
WL
D058186:Acute Kidney Injury / Q000209:etiology / Q000662:veterinary*; D000818:Animals; D000995:Antitubercular Agents / Q000009:adverse effects*; D001774:Blood Chemical Analysis / Q000662:veterinary; D004283:Dog Diseases / Q000139:chemically induced* / Q000209:etiology; D004285:Dogs; D017809:Fatal Outcome; D007538:Isoniazid / Q000009:adverse effects*; D008297:Male; D011379:Prognosis; D012206:Rhabdomyolysis / Q000209:etiology / Q000662:veterinary*; D012640:Seizures / Q000139:chemically induced / Q000150:complications / Q000662:veterinary*
D000995:Antitubercular Agents; D007538:Isoniazid