title: Planetary biology--paleontological, geological, and molecular histories of life.
abstract: The history of life on Earth is chronicled in the geological strata, the fossil record, and the genomes of contemporary organisms. When examined together, these records help identify metabolic and regulatory pathways, annotate protein sequences, and identify animal models to develop new drugs, among other features of scientific and biomedical interest. Together, planetary analysis of genome and proteome databases is providing an enhanced understanding of how life interacts with the biosphere and adapts to global change.
authors: Department of Chemistry, University of Florida, Gainesville FL, 32611-7200, USA. benner@chem.ufl.edu
authors: Steven A
authors: SA
authors: Benner
authors: M Daniel
authors: MD
authors: Caraco
authors: J Michael
authors: JM
authors: Thomson
authors: Eric A
authors: EA
authors: Gaucher
mesh_terms: D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D000818:Animals; D003062:Codon; D030541:Databases, Genetic; D018534:Earth, Planet; D019143:Evolution, Molecular; D005580:Fossils; D020440:Gene Duplication; D016678:Genome; D055593:Geological Phenomena; D005844:Geology; D006801:Humans; D019369:Life; D010163:Paleontology; D010600:Pharmacology; D011506:Proteins / Q000737:chemistry / Q000502:physiology; D020543:Proteome; D012106:Research
chemical_list: D003062:Codon; D011506:Proteins; D020543:Proteome