Modelling transfer characteristics of vestibular neurons in the fastigial nucleus of the behaving monkey on the basis of canal-otolith interaction.
The interaction of vestibular inputs with different dynamic and spatial behavior, i.e., canal-otolith interaction, leads to spatio-temporal convergence. Vestibular neurons in the fastigial nucleus often exhibit spatio-temporal convergence. The present report demonstrates that the discharge rates of most vestibular neurons in the primate fastigial nucleus can be simulated at different stimulus frequencies and orientations by a simple linear summation of the signals of the semicircular canals and the otoliths. In this way, a number of complex characteristics that depend on frequency, i.e. changing response-vector orientations, large phase changes, absence and presence of spatio-temporal convergence, can be easily explained.
Wilden
Andreas
A
Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistr. 23, 81377 Munich, Germany.
Glasauer
Stefan
S
Kleine
Justus F
JF
Büttner
Ulrich
U
D000200:Action Potentials / Q000502:physiology; D000344:Afferent Pathways / Q000166:cytology / Q000502:physiology*; D000818:Animals; D002529:Cerebellar Nuclei / Q000166:cytology / Q000502:physiology*; D008253:Macaca mulatta / Q000033:anatomy & histology / Q000502:physiology*; D008959:Models, Neurological; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D010037:Otolithic Membrane / Q000166:cytology / Q000502:physiology*; D010812:Physical Stimulation; D004856:Postural Balance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012665:Semicircular Canals / Q000166:cytology / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology; D013569:Synapses / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology