title: Fragrance contact dermatitis - a worldwide multicenter investigation (Part III).
abstract: The purpose of this study was to determine the frequency of responses to selected fragrance materials in patients who were fragrance sensitive. 218 fragrance sensitive subjects were evaluated in eight centres worldwide with a fragrance mixture (FM) and 17 less well-studied fragrance materials. Reaction to the fragrance mixture (FM) occurred in 76% of the subjects. The (FM) detected all reactions to nerol and hydroxycitronellol and 93% of the reactions to clove bud oil. Ten fragrance materials were not detected by the FM and deserve further study: benzenepropanol, beta, beta, 3-trimethyl, hexyl-salicylate, dl-citronellol, synthetic ylang ylang oil, benzyl mixture, cyclohexyl-acetate, eugenyl methyl ether, isoeugenyl methyl ether, 3-phenyl-1-propanol, and 3, 7-dimethyl-7-methoxyoctan-2-ol.
authors: Portland, Oregon, USA. portoracle@aol.com
authors: Walter
authors: W
authors: Larsen
authors: Hideo
authors: H
authors: Nakayama
authors: Torkil
authors: T
authors: Fischer
authors: Peter
authors: P
authors: Elsner
authors: Peter
authors: P
authors: Frosch
authors: Desmond
authors: D
authors: Burrows
authors: William
authors: W
authors: Jordan
authors: Stephanie
authors: S
authors: Shaw
authors: John
authors: J
authors: Wilkinson
authors: James
authors: J
authors: Marks
authors: M
authors: M
authors: Sugawara
authors: Marc
authors: M
authors: Nethercott
authors: James
authors: J
authors: Nethercott
mesh_terms: D000328:Adult; D000485:Allergens / Q000009:adverse effects; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010476:Perfume / Q000009:adverse effects*
chemical_list: D000485:Allergens; D010476:Perfume