Signaling proteins as innovative targets for antineoplastic therapy: our experience with the signaling protein c-myc.
Cimoli
G
G
Department of Oncology Biology and Genetics, University of Genoa, Italy.
Bagnasco
L
L
Pescarolo
M P
MP
Avignolo
C
C
Melchiori
A
A
Pasa
S
S
Biasotti
B
B
Taningher
M
M
Parodi
S
S
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001549:Benzamides; D066246:ErbB Receptors / Q000037:antagonists & inhibitors; D006801:Humans; D000068877:Imatinib Mesylate; D010741:Phospholipases A; D010879:Piperazines / Q000494:pharmacology; D017368:Protein Prenylation / Q000187:drug effects; D011506:Proteins / Q000187:drug effects* / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000187:drug effects; D016271:Proto-Oncogene Proteins c-myc / Q000187:drug effects; D016283:Proto-Oncogene Proteins p21(ras); D011743:Pyrimidines / Q000494:pharmacology; D018168:Receptors, Retinoic Acid / Q000187:drug effects; D000072482:Retinoic Acid Receptor alpha; D015398:Signal Transduction / Q000187:drug effects*; D000068878:Trastuzumab; D018631:ras Proteins
D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D001549:Benzamides; C117307:KRAS protein, human; D010879:Piperazines; D011506:Proteins; D011518:Proto-Oncogene Proteins; D016271:Proto-Oncogene Proteins c-myc; D011743:Pyrimidines; C000607071:RARA protein, human; D018168:Receptors, Retinoic Acid; D000072482:Retinoic Acid Receptor alpha; D000068877:Imatinib Mesylate; D066246:ErbB Receptors; C433809:PLAAT1 protein, human; D010741:Phospholipases A; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins; D000068878:Trastuzumab