Effect of low levels of serum vitamin B12 and folic acid on cognitive performance in old age: a population-based study.
We studied the effect of low levels of vitamin B12 and folic acid, alone or combined, on cognitive performance in a population-based sample of 698 older adults (mean age = 68.7 years). No evidence was found for a vitamin-related memory deficit, but research participants with low levels of vitamin B12 exhibited reduced information processing speed relative to participants with normal vitamin B12 levels.
Jelicic
M
M
Department of Psychiatry and Neuropsychology, University of Maastricht, The Netherlands. m.jelicic@psychology.unimaas.nl
Jonker
C
C
Deeg
D J
DJ
D000368:Aged; D000375:Aging / Q000097:blood* / Q000523:psychology; D003072:Cognition Disorders / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D005492:Folic Acid / Q000097:blood*; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D009483:Neuropsychological Tests; D014805:Vitamin B 12 / Q000097:blood*
D005492:Folic Acid; D014805:Vitamin B 12