Soft tissue uptake of Tc99m-MDP in acute lymphoblastic leukemia.
Acute lymphoblastic leukemia (ALL) is associated rarely with hypercalcemia. This may be due to elevated levels of parathyroid hormone-related peptide (PTHrP). We report a case of an 18-year-old female patient who was presented with a pathological fracture of left intertrochanteric region. Bone scintigraphy was consistent with features of hypercalcemia associated with metastatic calcification. A bone marrow biopsy led to the diagnosis of ALL. The mechanism of hypercalcemia in ALL, metastatic calcification and soft tissue uptake of bone seeking agents in this case are discussed in detail.
Marwah
Atul
A
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Kumar
Rakesh
R
Dasan J
Bharathi
B
Choudhury
Saikat
S
Bandopadhyaya
Gurupad
G
Malhotra
Arun
A
D000293:Adolescent; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000097:blood; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D014915:Whole-Body Counting
D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate