Proliferative verrucous leukoplakia: a case report.
Proliferative verrucous leukoplakia (PVL) is a particularly aggressive form of oral leukoplakia that is resistant to treatment and presents a high risk of recurrence and malignant transformation. This article describes the microscopic and clinical characteristics of one case of PVL, which initially presented as hyperkeratosis with mild dysplasia and posteriorly developed multifocal areas and verrucous carcinoma despite treatment.
Lopes
M A
MA
Department of Oral Diagnosis, Faculty of Odontology-UNICAMP, São Paulo, Brazil. mal001@dental.umaryland.edu
Pazoki
A E
AE
Ord
R A
RA
D018289:Carcinoma, Verrucous / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007642:Keratosis / Q000473:pathology; D007972:Leukoplakia, Oral / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology; D009364:Neoplasm Recurrence, Local; D012307:Risk Factors; D014062:Tongue Neoplasms / Q000473:pathology