Increased GABA neurotransmission via administration of gamma-vinyl GABA decreased nicotine self-administration in the rat.
Paterson
Neil E
NE
Department of Neuropharmacology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA.
Markou
Athina
A
D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D003216:Conditioning, Operant / Q000187:drug effects; D003864:Depression, Chemical; D005502:Food; D007275:Injections, Intravenous; D008297:Male; D009538:Nicotine / Q000008:administration & dosage / Q000494:pharmacology*; D018722:Nicotinic Agonists / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012054:Reinforcement, Psychology; D012646:Self Administration; D009435:Synaptic Transmission / Q000187:drug effects* / Q000502:physiology*; D020888:Vigabatrin / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D000927:Anticonvulsants; D018722:Nicotinic Agonists; D005680:gamma-Aminobutyric Acid; D009538:Nicotine; D020888:Vigabatrin