title: [Analyzing partial nucleotide and amino acid sequences of Chinese TTV isolates].
abstract: BACKGROUND
  To investigate the prevalence of transfusion transmitted virus (TTV) and its sequence characterization in China.
  
  
  METHODS
  TTV DNA was amplified by Semi-Nested-PCR, and the positive products were sequenced directly.
  
  
  RESULTS
  The homology of partial nucleotide and amino acid sequences of 7 Chinese TTV isolates were 64.7%-98.4% and 62.7%-96.4% respectively when compared with Japanese isolate. Among 7 Chinese TTV isolates, the homology of partial nucleotide and amino acid sequences were 63.5%-98.4% and 60.2%-96.4% respectively. They differently belong to two genotypes and two subgenotypes.
  
  
  CONCLUSIONS
  There exists TTV in China, and there might be several genotypes of Chinese TTV isolates.
authors: Department of Clinical Laboratory, Eastern Hepatobiliary Hospital, The Second Military Medical University, Shanghai 200438, China.
authors: F
authors: F
authors: Fang
authors: H
authors: H
authors: Wang
authors: A
authors: A
authors: Wang
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D005838:Genotype; D006801:Humans; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D022783:Torque teno virus / Q000737:chemistry / Q000235:genetics*