title: Corneal endotheliitis and idiopathic sudden sensorineural hearing loss.
abstract: OBJECTIVE
  To report a case with corneal endotheliitis and idiopathic sudden sensorineural hearing loss, in which herpes simplex virus type 1 DNA was demonstrated in the trabeculum and the aqueous humor by polymerase chain reaction.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  A 60-year-old man presented with corneal stromal edema in the right eye and sudden bilateral sensorineural hearing loss. The trabeculum excised during trabeculectomy and the aqueous humor were examined for the presence of herpes simplex virus type 1 DNA by polymerase chain reaction.
  
  
  RESULTS
  Polymerase chain reaction demonstrated herpes simplex virus type 1 DNA in the aqueous humor and the trabeculum.
  
  
  CONCLUSIONS
  Herpes simplex virus type 1 may cause corneal endotheliitis and idiopathic sudden sensorineural hearing loss simultaneously.
authors: Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
authors: Tatsuya
authors: T
authors: Mimura
authors: Shiro
authors: S
authors: Amano
authors: Miyuki
authors: M
authors: Nagahara
authors: Tetsuro
authors: T
authors: Oshika
authors: Kazuhito
authors: K
authors: Tsushima
authors: Norimasa
authors: N
authors: Nakanishi
authors: Tsuyoshi
authors: T
authors: Tanino
mesh_terms: D001082:Aqueous Humor / Q000821:virology; D015715:Corneal Edema / Q000209:etiology*; D004279:DNA, Viral / Q000032:analysis; D004728:Endothelium, Corneal / Q000473:pathology*; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D018259:Herpesvirus 1, Human / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D016849:Keratitis, Herpetic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014129:Trabecular Meshwork / Q000821:virology
chemical_list: D004279:DNA, Viral