Peritoneal dialysis in Asia: an external perspective.
There are almost 30,000 patients maintained on peritoneal dialysis (PD) in Asia, representing about 8% of all Asian dialysis patients. The largest numbers of PD patients are in Japan and China, but the highest PD penetration is in Hong Kong, Korea, and Singapore. Notable features of PD in Asia include the varying rates of use across the different countries. The reasons for this are reviewed here, with particular emphasis on the significance of whether dialysis providers are predominantly private or public. The excellent rates of both patient and technique survival in the richer Asian countries are also examined and interpreted in the context of recent data showing that Asian patients living in North America have generally superior survival on dialysis and better compliance with PD than their Caucasian counterparts. It is concluded that the healthier baseline health status in South East Asian patients, in particular, contributes to their impressive outcomes. The approach to both clearance and ultrafiltration is less aggressive in Asian countries than in the West. Studies looking at the relationship between clearance and clinical outcome in Asia are reviewed and it is concluded that the benefits of higher clearances have been harder to show than in North America because of the relatively better outcomes of the patients. The concern about sclerosing encapsulating peritonitis in Japan particularly is emphasized. The Hong Kong model of dialysis delivery with its high use of PD and the arguments for and against it are also reviewed.
Blake
Peter G
PG
Division of Nephrology, London Health Sciences Centre, University of Western Ontario, Canada. peter.blake@lhsc.on.ca
D001208:Asia / Q000453:epidemiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000628:therapy; D010530:Peritoneal Dialysis / Q000379:methods / Q000401:mortality / Q000706:statistics & numerical data; D006435:Renal Dialysis / Q000706:statistics & numerical data; D015996:Survival Rate; D016896:Treatment Outcome