title: Serum calcium and magnesium concentrations and the use of a calcium-magnesium-borogluconate solution in the treatment of Friesian mares with retained placenta.
abstract: The purpose of the present study was to compare serum calcium and magnesium concentrations in mares with or without a retained placenta (RP) and to evaluate treatment of mares with RP with oxytocin versus oxytocin combined with Ca-Mg-borogluconate solution. Blood samples were obtained within 12 h of foaling from Friesian mares with and without an RP (n = 90 and 65, respectively). Serum Ca and Mg concentrations were analyzed by atomic absorption spectrophotometry. In total, we treated 112 cases of RP in 101 Friesian mares by infusion of either oxytocin dissolved in saline solution or oxytocin dissolved in Ca-Mg-borogluconate solution. We defined RP as the failure to expel all or a part of the fetal membranes up to 3 h after delivery of the foal. We defined a positive response to the treatment as the passage of the entire placenta within 2 h after the infusion. Mares with RP had significantly lower serum calcium levels within 12 h of foaling than mares without RP. Serum magnesium levels showed no difference. Sixty-four percent of the mares treated with oxytocin in Ca-Mg-borogluconate solution responded positively to the treatment, compared to 44% of the mares treated with oxytocin in saline solution (P < 0.05).
authors: Veterinary Practice Mid-Fryslân, Akkrum, The Netherlands. sevinga@xs4all.nl
authors: M
authors: M
authors: Sevinga
authors: H W
authors: HW
authors: Barkema
authors: J W
authors: JW
authors: Hesselink
mesh_terms: D000818:Animals; D001888:Boric Acids / Q000008:administration & dosage* / Q000627:therapeutic use; D002118:Calcium / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D005260:Female; D006734:Horse Diseases / Q000097:blood* / Q000188:drug therapy*; D006736:Horses; D008274:Magnesium / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D010121:Oxytocin / Q000008:administration & dosage / Q000627:therapeutic use; D018457:Placenta, Retained / Q000097:blood / Q000188:drug therapy / Q000662:veterinary*; D011247:Pregnancy; D012965:Sodium Chloride; D012996:Solutions
chemical_list: D001888:Boric Acids; D012996:Solutions; D012965:Sodium Chloride; D010121:Oxytocin; C034286:borogluconate; D008274:Magnesium; D002118:Calcium