Tamoxifen therapy in steroid-resistant Riedels disease.
Riedels thyroiditis is a rare chronic inflammatory disorder characterised by extensive fibrosis of the thyroid gland and sometimes the surrounding tissues. We report a case of Riedels Thyroiditis in a middle aged female presenting with goitre, stridor and dyspnoea. She initially responded to corticosteroid treatment and subsequently to tamoxifen. The rationale for these treatments are discussed.
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Department of Ear, Nose and Throat, Crosshouse Hospital, Kilmarnock.
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Dempster
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D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D005260:Female; D005355:Fibrosis; D006801:Humans; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D020845:Selective Estrogen Receptor Modulators / Q000627:therapeutic use*; D013629:Tamoxifen / Q000627:therapeutic use*; D013967:Thyroiditis, Autoimmune / Q000188:drug therapy* / Q000473:pathology
D000893:Anti-Inflammatory Agents; D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen; D011239:Prednisolone