Histo and cyto-pathologic diagnoses at a rural hospital in Kenya.
BACKGROUND
Cancer has emerged as one of the common causes of morbidity and mortality in rural areas and as a major cause of premature deaths.


OBJECTIVE
To provide histo-pathology and cyto-pathology data in a rural district hospital and highlight on the common malignancies seen in a rural setting in Kenya.


METHODS
Prospective study.


METHODS
Histopathology Department, Machakos Provincial Hospital, Machakos district, Kenya.


METHODS
Two hundrend and sixty eight patients referred to Machakos laboratory for histopathology, fine needle aspirate or pap smear cyto-pathology were analysed.


METHODS
Staining with routine stains such Pap stain, Haeomatoxylin and Eosin was effective method of making a primary accurate and definitive histo-pathology and cyto-pathology diagnosis in a rural district hospital setting.


RESULTS
Histo-pathology biopsies comprised 71.6% of the total slides seen. Pap smear cervical cytology comprised 13.8% while fine needle aspirate and post- mortem biopsies comprised 12.3%, 2.2% respectively. The commonest histo-pathology biopsies seen were breast comprising 24% of the total cases, followed by endometrium contributing 14.9%, then followed by skin 11.5%, lymph node 11.5%, cervical 11%, and gastrointestinal 6.3%. Most of pap smear cyto-pathology showed evidence of infection comprising 54% while fine needle aspirate infections and malignancy showed equal rate 24% of all cyto-pathology seen during this study.


CONCLUSIONS
This is the first time histo-pathology and cyto-pathology data have been provided from a rural district hospital setting in Kenya. The malignant and pre-malignant pattern seen at Machakos General Hospital may be used to gain a broader picture of the common malignant conditions prevalent in any defined population in this country. This also serves as an important cancer epidemiological data in this region during the period of study.
Mutuma
G Z
GZ
Kenya Medical Research Institute, Centre forClinical Research, Nairobi.
D001706:Biopsy; D005260:Female; D006769:Hospitals, General; D006780:Hospitals, Rural; D006801:Humans; D007630:Kenya; D009369:Neoplasms / Q000473:pathology* / Q000601:surgery; D011230:Precancerous Conditions / Q000473:pathology; D011446:Prospective Studies