title: Preparation and cytotoxic activity of some new rhodomycin derivatives bearing modifications in the sugar moiety.
abstract: The synthesis and structural determination of a number of new rhodomycin derivatives, modified in the sugar part are described. The cytotoxicity against leukemic L1210 cells of these compounds is reported, along with beta-rhodomycinone and two regioisomers of the above compounds, which were isolated during the synthetic procedure.
authors: University of Athens, Department of Pharmacy, Greece.
authors: Nectarios
authors: N
authors: Algiannis
authors: Nicole
authors: N
authors: Pouli
authors: Panagiotis
authors: P
authors: Marakos
authors: Alexios-Leandros
authors: AL
authors: Skaltsounis
authors: Jean-Claude
authors: JC
authors: Florent
authors: Elisabeth M
authors: EM
authors: Perchellet
authors: Bonnie J
authors: BJ
authors: Sperfslage
authors: Corbin J
authors: CJ
authors: McIlvain
authors: Jean-Pierre
authors: JP
authors: Perchellet
mesh_terms: D000818:Animals; D018943:Anthracyclines / Q000494:pharmacology*; D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000494:pharmacology; D007939:Leukemia L1210 / Q000188:drug therapy*; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; C004977:rhodomycin