title: A population-based study of the extent of surgical resection of potentially curable colon cancer.
abstract: BACKGROUND
  We attempted to determine factors contributing to the extent of initial curative resection for colon cancer in a population-based cohort. Total abdominal colectomy with ileorectal anastomosis (TAC-IR) may be considered for young patients or those with a colorectal cancer family history to prevent metachronous lesions and facilitate surveillance.
  
  
  METHODS
  All Ontario patients newly diagnosed with colon cancer over 12 months beginning in July 1997 were staged at the time of surgery. The extent of resection was compared with variables, including familial risk obtained from the Ontario Familial Colon Cancer Registry.
  
  
  RESULTS
  Complete staging was possible for 86% of patients. A total of 1223 patients had a potentially curative resection: 17%, 46%, and 36% were stage I, II, and III, respectively. Patients were more likely to receive a TAC-IR if they were < or = 50 years old (odds ratio [OR], 3.5; 95% confidence interval [CI], 1.8-6.6), if they had a synchronous lesion (OR, 28.37; 95% CI, 12.2-61.2), or if they were at a teaching hospital (OR, 2.8; 95% CI, 1.6-4.7), but not if they had a family history (OR,.7; 95% CI,.3- 1.5).
  
  
  CONCLUSIONS
  Young age, teaching hospital, and multiple cancers but not family history were important factors for performing a TAC-IR.
authors: Department of Surgical Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada. easson.alexandra@uhn.on.ca
authors: Alexandra M
authors: AM
authors: Easson
authors: Michelle
authors: M
authors: Cotterchio
authors: Jacqueline A
authors: JA
authors: Crosby
authors: Heather
authors: H
authors: Sutherland
authors: Darlene
authors: D
authors: Dale
authors: Melyssa
authors: M
authors: Aronson
authors: Eric
authors: E
authors: Holowaty
authors: Steven
authors: S
authors: Gallinger
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003110:Colonic Neoplasms / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009864:Ontario / Q000453:epidemiology; D012042:Registries; D012307:Risk Factors; D016896:Treatment Outcome