title: Effectiveness of second-generation fibrin glue in endonasal operations.
abstract: We evaluated the efficacy and safety of the Quixil fibrin sealant after its application to endonasal operative sites. A total of 153 patients underwent nasal surgery. The rate of hemorrhagic complications was compared in the group with nasal packing and in the group in whom fibrin glue was used to stop postoperative bleeding. Our results indicate that the application of Quixil fibrin glue to the operative sites in various endonasal operations provides effective hemostasis and sealing. This fibrin glue is a more effective hemostatic agent than foam nasal packing and provides no complications, as can occur with packing. Patients with hypertension have no greater risk for postoperative bleeding if Quixil is used.
authors: Department of Otolaryngology, Assaf Harofeh Medical Center, Israel. shteren20@hotmail.com
authors: Michael
authors: M
authors: Vaiman
authors: Ephraim
authors: E
authors: Eviatar
authors: Samuel
authors: S
authors: Segal
mesh_terms: D000328:Adult; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000601:surgery; D009668:Nose Diseases / Q000601:surgery*; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D011446:Prospective Studies; D013630:Tampons, Surgical
chemical_list: D015718:Fibrin Tissue Adhesive; D006490:Hemostatics