title: TSH secretory pattern and thyroid function in children with growth hormone neurosecretory dysfunction.
abstract: We evaluated the TSH secretory pattern and free T4 in 10 prepubertal children with short stature, normal response to GH provocative tests, and reduced GH integrated concentration (IC-GH) (GH neurosecretory dysfunction). Although their nadir TSH, peak TSH, TSH surge, and free T4 were lower than those of 12 children with short stature and normal IC-GH, none of the differences reached statistical significance. Thus, our results suggest that children with low IC-GH (GH neurosecretory dysfunction) exhibit a TSH secretory pattern and thyroid function similar to those with normal IC-GH.
authors: Department of Pediatrics, University of Maryland School of Medicine, Baltimore, USA.
authors: M F F W
authors: MF
authors: Quevedo
authors: B
authors: B
authors: Pironis
authors: T
authors: T
authors: Palese
authors: D R
authors: DR
authors: Counts
authors: F
authors: F
authors: De Luca
mesh_terms: D001846:Bone Development; D002648:Child; D002675:Child, Preschool; D005260:Female; D006130:Growth Disorders / Q000209:etiology; D019382:Human Growth Hormone / Q000172:deficiency* / Q000378:metabolism; D006801:Humans; D008297:Male; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000503:physiopathology*; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood
chemical_list: D019382:Human Growth Hormone; D013972:Thyrotropin; D013974:Thyroxine