Reversal of airflow obstruction and improvement in cystic lesions with treatment of HIV associated PCP.
A 54-year-old Japanese male smoker in whom lung function had been normal developed airflow obstruction coincident with the development of human immunodeficiency virus (HIV)-associated Peumocystis carinii pneumonia (PCP). Chest high resolution computed tomography (HRCT) revealed cystic lesions involving the upper lung fields. Both cystic lesions and airflow obstruction improved simultaneously with treatment of PCP and acquired immunodeficiency syndrome (AIDS). Bronchiolar PCP lesions creating a check-valve mechanism may explain these reversible changes.
Tanigaki
T
T
Department of Medicine, Tokai University School of Medicine, Isehara, Kanagawa, 259-1193 Japan. tanigaki@is.icc.u-tokai.ac.jp
Nishiya
K
K
Kuwahira
I
I
Matsuyama
S
S
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D000402:Airway Obstruction / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D003560:Cysts / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*