Early puberty in adopted children.
Early puberty is frequently observed in adopted children. In various studies, early puberty has been associated with decreased final height. In Europe, studies were undertaken to treat early puberty in adopted children with GnRH agonist. This article reviews the current understanding of early puberty in adopted children, including prevalence, background and treatment options. Data from the European studies are briefly described. Besides auxological aspects, psychological items are addressed as well. Studies on the psychological effect of early puberty in adopted children are reported. Future issues include further study in the mechanism of early puberty in adopted children, evaluation of final height results of the growth studies and quality of life assessments in this specific group of children.
Mul
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Erasmus University Medical Centre/Sophia Children's Hospital (Subdivision Endocrinology), Rotterdam, The Netherlands. Mul@alkg.azr.nl
Oostdijk
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Drop
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D000300:Adoption / Q000523:psychology; D002648:Child; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011629:Puberty, Precocious / Q000188:drug therapy / Q000453:epidemiology* / Q000523:psychology
D007987:Gonadotropin-Releasing Hormone; D013006:Growth Hormone