[Clinical characteristics of osteosarcomas and cell aneuploidy in children and adolescents -- retrospective studies].
The relationship between the clinical status skeletal involvement, frequency of metastases and histopathological grading of osteosarcomas 18 children and adolescents and abnormal DNA content (aneuploidy) was analysed. Our findings demonstrate a correlation between Index DNA (DI), percentage of aneuploidy population to histopathological grading and prognosis. No significant correlation was found between aneuploidy and the site of skeletal involvement.
Rytwinski
K
K
Samodzielna Pracownia Cytometrii, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211 Warszawa, Poland. cytometr@imid.med.pl
Rychlowska
M
M
Wnuk
A
A
Klepacka
T
T
Michalak
E
E
D000293:Adolescent; D000782:Aneuploidy; D001859:Bone Neoplasms / Q000235:genetics* / Q000473:pathology*; D002648:Child; D004273:DNA, Neoplasm / Q000032:analysis; D006801:Humans; D012516:Osteosarcoma / Q000235:genetics* / Q000473:pathology* / Q000556:secondary; D011379:Prognosis; D012189:Retrospective Studies
D004273:DNA, Neoplasm