New synthesis of L-FMAU from L-arabinose.
A new synthesis of 2'-deoxy-2'-fluoro-5-methyl-beta-L-arabinofuranosyl uracil (13, L-FMAU) was achieved in 10 steps from L-arabinose.
Sznaidman
Marcos L
ML
Division of Organic Chemistry, Triangle Pharmaceuticals Inc., RTP, North Carolina 27717, USA.
Almond
Merrick R
MR
Pesyan
Amir
A
D001086:Arabinofuranosyluracil / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D001089:Arabinose / Q000737:chemistry*
D001086:Arabinofuranosyluracil; D001089:Arabinose; C034935:clevudine