[Inhalation anesthesia with halogen-containing anesthetics in children].
The study was carried out in 158 children aged 3-16 years operated on in an inpatient setting. The patients were divided into 3 groups with different types of induction narcosis: 1) ethrane inhalation up to 3 vol% and N2O with O2 in 1:1 ratio (56 pts); 2) fluothane up to 3.5 vol% and N2O with O2 in 2:1 ratio (87 pts), and 3) isoflurane inhalation up to 3 vol% and N2O with O2 in 1:1 ratio (15 children). Central hemodynamics, cardiointervalograms, and external respiration function were studied. Ethrane and isoflurane induction was longer (4-12 min) than fluothane induction (3-5 min). Anesthesia with ethrane and isoflurane in combination with N2O with O2 led to a less pronounced reaction of the central hemodynamics than fluothane anesthesia, which led to a decrease of the sympathic tone and increase in the activity of the parasympathetic component of the autonomic nervous system. Analyzing a vast scope of clinical material on the use of inhalation anesthetics and all the pros and contras, the authors conclude that inhalation anesthetics can be used in children.
Ostreĭkov
I F
IF
Pivovarov
S A
SA
Babaev
B D
BD
Shishkov
M V
MV
D000293:Adolescent; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D004737:Enflurane / Q000008:administration & dosage*; D006439:Hemodynamics; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage*; D012119:Respiration
D018685:Anesthetics, Inhalation; D004737:Enflurane; D007530:Isoflurane