Electrogastrography in children with cystic fibrosis.
Patients with cystic fibrosis often develop upper gastrointestinal symptoms, which may be due to abnormal gastric motor function. The aim of the study is to determine the characteristics of gastric electrical activity in patients with cystic fibrosis and to compare electrogastrography patterns in symptomatic and asymptomatic patients. Electrogastrography was recorded in 14 symptomatic and 8 asymptomatic children with CF. Both 30-min baseline and 30-min postprandial recordings was obtained. Dominant frequency cycles per minute, rhythm index, and power in decibels were obtained for the fasting and postprandial periods. The percentage of normal gastric waves was not affected by the meal and was significantly low in symptomatic and asymptomatic cystic fibrosis patients. Tachygastria was the most frequent dysrhythmia in both groups. Decreased postprandial power was seen in three symptomatic patients and one patient had no change. The percentage of normal gastric slow waves was low in symptomatic and asymptomatic cystic fibrosis patients. Tachygastria was the most frequent dysrhythmia. Decreased postprandial power was seen only in symptomatic patients.
Aktay
Atiye Nur
AN
Division of Pediatric Gastroenterology, The Children's Hospital of Wisconsin and The Medical College of Wisconsin, Milwaukee 53226, USA.
Splaingard
Mark L
ML
Miller
Tami
T
Freeman
Mary Ellen
ME
Hoeppner
Heidi
H
Werlin
Steven L
SL
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000503:physiopathology*; D004594:Electrophysiology; D005215:Fasting; D006801:Humans; D008297:Male; D019518:Postprandial Period; D011930:Reaction Time; D013270:Stomach / Q000503:physiopathology*