Muscle structural capacity for oxygen flux from capillary to fiber mitochondria.
The concept of major functional resistance to O2 flux at the capillary-fiber interface implies that muscle structural capacity for O2 flux from capillary to fiber mitochondria needs to be assessed in terms of capillary surface per fiber surface. Morphological data support this notion and show the importance of assessing the size of the capillary-fiber interface relative to muscle fiber O2 demand.
Mathieu-Costello
Odile
O
Department of Medicine, University of California, San Diego, La Jolla 92093-0623, USA. odile@ucsd.edu
Hepple
Russell T
RT
D000818:Animals; D002196:Capillaries / Q000378:metabolism; D015444:Exercise / Q000502:physiology; D006801:Humans; D008931:Mitochondria, Muscle / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology; D010805:Physical Conditioning, Animal / Q000502:physiology
D010100:Oxygen