title: Changes in cell morphology and cell-to-cell adhesion induced by extracellular Ca2+ in cultured taste bud cells.
abstract: Cell morphology and cell-to-cell adhesion of taste bud cells were significantly altered by extracellular Ca2+ during in vitro culture. Under high Ca2+ condition (above 0.5 mM), the cells were tightly associated with each other and formed packed aggregates. Under low Ca2+ condition (below 0.1 mM), the cells were dispersed and had an elongated shape. These two forms were reversible and specifically dependent on Ca2+. The results indicate that extracellular Ca2+ regulates cell shape and cell-to-cell adhesion of taste bud cells.
authors: Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
authors: Mikiya
authors: M
authors: Kishi
authors: Yasufumi
authors: Y
authors: Emori
authors: Yoshinori
authors: Y
authors: Tsukamoto
authors: Keiko
authors: K
authors: Abe
mesh_terms: D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects*; D002478:Cells, Cultured; D051381:Rats; D013650:Taste Buds / Q000187:drug effects* / Q000378:metabolism
chemical_list: D002118:Calcium