[Long-term efficacy of vaccination against hepatitis B in newborns: 13 years' follow-up].
OBJECTIVE
To evaluate long-term efficacy of hepatitis B vaccination in newborns.


METHODS
In the past 13 years we followed up the children who had been immunized with hepatitis B vaccine at birth in 1986 every other year. At each follow-up visit, every child was tested for HBsAg, anti-HBs and anti-HBc.


RESULTS
HBsAg positive rate of these birth cohort was low (range between 0.46% and 0.98%) during 13 years' follow-up. Long-term efficacy of the vaccination in preventing HBsAg carriage was confirmed.


CONCLUSIONS
Thirteen years later no booster was after needed.
Wu
W
W
Shanghai Huangpu District Center for Disease Control and Prevention, Shanghai 200011, China.
Sun
C
C
Jiang
M
M
Xu
Y
Y
Zhang
G H
GH
Liu
C B
CB
Cao
H L
HL
Lin
X M
XM
Xu
Z Y
ZY
D005260:Female; D005500:Follow-Up Studies; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014611:Vaccination
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines