Management of advanced-stage ovarian cancer: median survival rate about 2-3 years.
(1) Most cases of ovarian cancer are diagnosed at an advanced stage (peritoneal extension beyond the pelvis or distant metastases). (2) The standard treatment is surgery followed by chemotherapy with paclitaxel + platinum salt. Data favouring carboplatin over cisplatin in this setting are of poor quality. (3) There is no standard second-line chemotherapy regimen.
D016190:Carboplatin / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D019468:Disease Management; D005260:Female; D005602:France; D006801:Humans; D015201:Meta-Analysis as Topic; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000628:therapy*; D015996:Survival Rate
D016190:Carboplatin; D002945:Cisplatin