A three-state mechanism of integrin activation and signal transduction for integrin alpha(v)beta(3).
Gottschalk
Kay E
KE
Institut für Organische Chemie und Biochemie, TU München, Lichtenbergstrasse, 4 85747 Garching, Germany.
Günther
Robert
R
Kessler
Horst
H
D002118:Calcium / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D018360:Crystallography, X-Ray; D004791:Enzyme Inhibitors / Q000494:pharmacology; D008024:Ligands; D008958:Models, Molecular; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D019030:Receptors, Vitronectin / Q000037:antagonists & inhibitors / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D004791:Enzyme Inhibitors; D008024:Ligands; D009842:Oligopeptides; D019030:Receptors, Vitronectin; C047981:arginyl-glycyl-aspartic acid; D003094:Collagen; D002118:Calcium