Inclusion complex of conjugated linoleic acid (CLA) with cyclodextrins.
Conjugated linoleic acid (CLA) inclusion complexes with alpha-cyclodextrin (alpha-CD), beta-cyclodextrin (beta-CD), and gamma-cyclodextrin (gamma-CD) (designated CLA/CDs inclusion complexes) were prepared to determine the mole ratio of CLA complexed with CDs and the oxidative stability of CLA in the CLA/CDs inclusion complexes. When measured by GC, (1)H NMR, and T(1) value analyses, 1 mole of CLA was complexed with 5 mol of alpha-CD, 4 mol of beta-CD, and 2 mol of gamma-CD. The oxidation of CLA induced at 35 degrees C for 80 h was completely prevented by the formation of CLA/CDs inclusion complexes.
Park
Cherl W
CW
Division of Applied Life Sciences and Institute of Agriculture and Life Sciences, Graduate School, Gyeongsang National University, Chinju 660-701, Korea.
Kim
Seck J
SJ
Park
Sook J
SJ
Kim
Jeong H
JH
Kim
Jung K
JK
Park
Gu B
GB
Kim
Jeong O
JO
Ha
Yeong L
YL
D002849:Chromatography, Gas; D003505:Cyclodextrins / Q000737:chemistry*; D004355:Drug Stability; D019787:Linoleic Acid / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D047391:alpha-Cyclodextrins; D047392:beta-Cyclodextrins; D047408:gamma-Cyclodextrins
D003505:Cyclodextrins; D047391:alpha-Cyclodextrins; D047392:beta-Cyclodextrins; D047408:gamma-Cyclodextrins; D019787:Linoleic Acid; C031215:betadex; C023792:gamma-cyclodextrin; C032613:alpha-cyclodextrin