title: Synthesis and antiviral evaluation of some new glycosylthioureas containing a quinazolinone nucleus.
abstract: A new synthesis of glycosylthioureas containing a quinazolinone nucleus is described utilizing per-O-acetylglycopyranosylisothiocyanates and several aminoquinazolinones as starting compounds. Structural proofs of these compounds are provided from elemental analyses, IR, 1H and 13C NMR spectra and mass spectra. The biological activity of these compounds has been studied.
authors: Chemistry Department, Faculty of Science, Tanta University, Egypt.
authors: Mohamed A
authors: MA
authors: Saleh
authors: Mohamed F
authors: MF
authors: Abdel-Megged
authors: Mohamed A
authors: MA
authors: Abdo
authors: Abdel-Basset M
authors: AB
authors: Shokr
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002247:Carbon Isotopes / Q000737:chemistry / Q000378:metabolism; D006678:HIV / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D009858:Oncogenic Viruses / Q000187:drug effects; D011799:Quinazolines / Q000378:metabolism*; D013055:Spectrophotometry, Infrared; D013890:Thiourea / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D002247:Carbon Isotopes; D011799:Quinazolines; D013890:Thiourea