title: Intra-articular hyaluronic acid in the treatment of haemophilic chronic arthropathy.
abstract: We report our preliminary experience with the use of hyaluronic acid (Synvisc) in 29 joints from 25 different haemophilic patients (17 knees, six shoulders, four ankles, one elbow and one hip). All the joints were grade III of our classification, characterized by synovial thickening, axial deformities and muscle atrophy (chronic arthropathy). In view of the very satisfactory results obtained with this procedure, we have substituted Synvisc for the previous use of intra-articular long-standing corticosteroids that we had been used for some years. This method is theoretically more physiological and does not destroy the joint cartilage further, as corticosteroids can.
authors: Unidad de Ortopedia del Centro Nacional de Hemofilia, Banco de Sangre del DC Caracas, Venezuela. feferpal@telcel.net.ve
authors: F
authors: F
authors: Fernández-Palazzi
authors: R
authors: R
authors: Viso
authors: A
authors: A
authors: Boadas
authors: A
authors: A
authors: Ruiz-Sáez
authors: H
authors: H
authors: Caviglia
authors: N Blumenfeld
authors: NB
authors: De Bosch
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005500:Follow-Up Studies; D006395:Hemarthrosis / Q000188:drug therapy*; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D007270:Injections, Intra-Articular; D008875:Middle Aged; D010146:Pain / Q000517:prevention & control; D017060:Patient Satisfaction; D016059:Range of Motion, Articular; D016896:Treatment Outcome
chemical_list: D006820:Hyaluronic Acid