Spiral-CT-based assessment of tracheal stenoses using 3-D-skeletonization.
OBJECTIVE
Demonstration of a technique for three-dimensional (3-D) assessment of tracheal-stenoses, regarding site, length and degree, based on spiral computed tomography (S-CT).


METHODS
S-CT scanning and automated segmentation of the laryngo-tracheal tract (LTT) was followed by the extraction of the LTT medial axis using a skeletonization algorithm. Orthogonal to the medial axis the LTT 3-D cross-sectional profile was computed and presented as line charts, where degree and length was obtained. Values for both parameters were compared between 36 patients and 18 normal controls separately. Accuracy and precision was derived from 17 phantom studies.


RESULTS
Average degree and length of tracheal stenoses was found to be 60.5% and 4.32 cm in patients compared with minor caliber changes of 8.8% and 2.31 cm in normal controls (p << 0.0001). For the phantoms an excellent correlation between the true and computed 3-D cross-sectional profile was found (p << 0.005) and an accuracy for length and degree measurements of 2.14 mm and 2.53% respectively could be determined. The corresponding figures for the precision were found to be 0.92 mm and 2.56%.


CONCLUSIONS
LTT 3-D cross-sectional profiles permit objective, accurate and precise assessment of LTT caliber changes. Minor LTT caliber changes can be observed even in normals and, in case of an otherwise normal S-CT study, can be regarded as artifacts.
Sorantin
Erich
E
Department of Radiology, University Hospital Graz, Austria. erich.sorantin@kfunigraz.ac.at
Halmai
Csongor
C
Erdöhelyi
Balázs
B
Palágyi
Kálmán
K
Nyúl
László G
LG
Ollé
Krisztián
K
Geiger
Bernhard
B
Lindbichler
Franz
F
Friedrich
Gerhard
G
Kiesler
Karl
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D017143:Fuzzy Logic; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007223:Infant; D008875:Middle Aged; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D036542:Tomography, Spiral Computed / Q000295:instrumentation* / Q000379:methods*; D014135:Tracheal Stenosis / Q000000981:diagnostic imaging*