title: Solitary fibrous tumour in the deep soft tissue of the neck in a Chinese man.
abstract: Originally described in the pleura, solitary fibrous tumour (SFT) is now reported in a variety of extrapleural sites. However, description of SFT in the deep soft tissue of the neck is very rare. In this report, we document the neoplasm, deep to the right platsyma muscle but superficial to the deep fascia just above the clavicle, in an otherwise well 50-year-old Chinese man. Histological examination of the excised specimen disclosed spindle-shaped cells disposed in short fascicles as well as randomly in association with areas of varying cellularity, keloidal hyalinisation of the stroma and haemangiopericytoma-like vessels. The tumour cells were CD34-, bcl-2- and CD99-positive. Since histological features may not accurately predict the biological behaviour of this tumour, careful long-term follow-up is advocated.
authors: Department of Pathology, Singapore General Hospital.
authors: Seng Geok Nicholas
authors: SG
authors: Goh
authors: Khoon Leong
authors: KL
authors: Chuah
authors: Chee Seng
authors: CS
authors: Sim
authors: Beng Hock
authors: BH
authors: Ong
mesh_terms: D000071443:12E7 Antigen; D015703:Antigens, CD / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D015815:Cell Adhesion Molecules / Q000032:analysis; D006258:Head and Neck Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D051917:Leukosialin; D008297:Male; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D012795:Sialoglycoproteins / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000071443:12E7 Antigen; D015703:Antigens, CD; D014408:Biomarkers, Tumor; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; D051917:Leukosialin; D019253:Proto-Oncogene Proteins c-bcl-2; C465014:SPN protein, human; D012795:Sialoglycoproteins