Flow cytometric analysis of a localized malignant mesothelioma.
Malignant mesothelioma usually presents as a diffuse neoplasm. We report a localized malignant mesothelioma in the parietal pleura of a patient who was not exposed to asbestos. A complete clinical, pathologic, and immunohistochemical description is provided. Flow cytometric analysis showed an aneuploid DNA content in neoplastic cells. The patient is alive and well 8 months after complete surgical resection. Localized malignant mesothelioma must be included in the differential diagnosis in chest wall-based neoplasms.
Gómez-Román
José Javier
JJ
Department of Anatomical Pathology, University Hospital, Marqués de Valdecilla, National Health Institute, Medical Faculty, Cantabria University, Santander, Spain. apagrj@humv.es
Mons-Lera
Roberto
R
Olmedo
Isabel Seco
IS
Val-Bernal
José Fernando
JF
D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000032:analysis; D003937:Diagnosis, Differential; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008654:Mesothelioma / Q000737:chemistry / Q000235:genetics / Q000473:pathology*; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology*
D004273:DNA, Neoplasm