An etiological investigation of domestic cats with conjunctivitis and upper respiratory tract disease in Japan.
Chlamydophila felis (C. felis), feline herpesvirus-1 (FHV-1) and feline calicivirus (FCV) were detected in 39 (59.1%), 11 (16.7%) and 14 (21.2%) cats respectively, from 66 domestic cats presented with conjunctivitis and upper respiratory tract disease (URTD) in 9 prefectures of Japan. Dual and multiple infections were found in 7 (10.6%) cats with both C. felis and FHV-1, 10 (15.2%) cats with both C. felis and FCV, and 1 (1.5%) cat with all three agents. C. felis was isolated from 11 (28.2%) of 39 PCR positive cats. Antigenic difference was found in a 96 kDa protein of our isolates and Fe/145 strain isolated in USA. In conclusion, C. felis is the most common agent of feline conjunctivitis and URTD, and the coinfection with C. felis, FHV-1 and FCV are also common in cats in Japan.
Cai
Yan
Y
Department of Veterinary Microbiology, Faculty of Agriculture, Gifu University, Japan.
Fukushi
Hideto
H
Koyasu
Saori
S
Kuroda
Etsuko
E
Yamaguchi
Tsuyoshi
T
Hirai
Katsuya
K
D000818:Animals; D000940:Antigenic Variation; D015153:Blotting, Western / Q000662:veterinary; D017250:Caliciviridae Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D017927:Calicivirus, Feline / Q000235:genetics / Q000302:isolation & purification; D002371:Cat Diseases / Q000453:epidemiology / Q000382:microbiology* / Q000821:virology; D002415:Cats; D023501:Chlamydophila / Q000235:genetics / Q000302:isolation & purification; D023521:Chlamydophila Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D003231:Conjunctivitis / Q000150:complications / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006564:Herpesviridae / Q000235:genetics / Q000302:isolation & purification; D006566:Herpesviridae Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D007564:Japan / Q000453:epidemiology; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012140:Respiratory Tract Diseases / Q000150:complications / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*
D004269:DNA, Bacterial