title: Effect of naked neck gene (NA) and frizzle gene (F) on immunocompetence in chickens.
abstract: 1. A total of 98 birds belonging to 4 genetic groups from two specialised populations--heterozygous naked neck (NA*NA/NA*N) and normally feathered (NA*N/NA*N) from one specialised population and heterozygous frizzle (F*F/F*N) and normally feathered (F*N/F*N) from another specialised population--were evaluated for general immunocompetence by assessing antibody response to SRBC, haemolytic complement level in the serum, in-vivo cell mediated immune (CMI) response to Concanavalin-A (Con-A) and a phagocytic index at 10-12 weeks of age. 2. The naked neck gene did not seem to influence the antibody response to SRBC, CMI to Con-A or the phagocytic index. However, significantly higher haemolytic complement level in serum was observed in birds carrying a copy of the NA mutation as compared to the normally feathered birds. 3. Similar trends were observed for the frizzle gene.
authors: Immunogenetic Laboratory, Central Avian Research Institute, Izatnagar, India.
authors: S
authors: S
authors: Haunshi
authors: D
authors: D
authors: Sharma
authors: L M S
authors: LM
authors: Nayal
authors: D P
authors: DP
authors: Singh
authors: R V
authors: RV
authors: Singh
mesh_terms: D000818:Animals; D002645:Chickens / Q000235:genetics* / Q000276:immunology*; D003168:Complement Fixation Tests / Q000662:veterinary; D003208:Concanavalin A / Q000276:immunology; D005260:Female; D006386:Hemagglutination Tests / Q000662:veterinary; D007121:Immunocompetence / Q000235:genetics* / Q000276:immunology; D008297:Male; D009154:Mutation; D010587:Phagocytosis / Q000276:immunology
chemical_list: D003208:Concanavalin A