Ectopic D-type cyclin expression induces not only DNA replication but also cell division in Arabidopsis trichomes.
Although the mechanisms controlling the two cell-cycle checkpoints G(1)-S and G(2)-M are well studied, it remains elusive how they are linked in higher eukaryotes. In animals, D-type cyclins have been implicated in the control of cell-cycle progression in mitotic as well as in endoreduplicating cells. By contrast, we show that the expression of the D-type cyclin CYCD3;1 in endoreduplicating Arabidopsis trichome cells not only induced DNA replication but also cell divisions.
Schnittger
Arp
A
Zentrum für Molekularbiologie der Pflanzen, Entwicklungsgenetik, Universität Tübingen, Auf der Morgenstelle 3, 72076 Tübingen, Germany.
Schöbinger
Ulrike
U
Bouyer
Daniel
D
Weinl
Christina
C
Stierhof
York-Dieter
YD
Hülskamp
Martin
M
D017360:Arabidopsis / Q000235:genetics*; D002453:Cell Cycle; D002455:Cell Division; D056741:Cyclin D; D016213:Cyclins / Q000096:biosynthesis*; D004247:DNA / Q000096:biosynthesis* / Q000378:metabolism; D005966:Glucuronidase / Q000378:metabolism; D008938:Mitosis; D009693:Nucleic Acid Hybridization; D012313:RNA / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction
D056741:Cyclin D; D016213:Cyclins; D012313:RNA; D004247:DNA; D005966:Glucuronidase