title: Lactobacillus fermentum RC-14 inhibits Staphylococcus aureus infection of surgical implants in rats.
abstract: Staphylococcus aureus is a common cause of community and hospital-acquired infections. Moreover, the clinical impact of S. aureus is on the rise because of the global increase in the incidence of multidrug-resistant strains and its growing prevalence as a major cause of surgical infections. As a result, there is a pressing need to identify new antistaphylococcal agents and preventative strategies that will help in the management of these types of infections. This report describes the successful use of a probiotic, Lactobacillus fermentum RC-14, and its secreted biosurfactant to inhibit surgical implant infections caused by S. aureus. L. fermentum RC-14 and its secreted biosurfactant both significantly inhibited S. aureus infection and bacteria adherence to surgical implants.
authors: Hand and Upper Limb Centre, Lawson Health Research Institute, Department of Surgery, University of Western Ontario, London, Canada.
authors: Bing Siang
authors: BS
authors: Gan
authors: Juan
authors: J
authors: Kim
authors: Gregor
authors: G
authors: Reid
authors: Peter
authors: P
authors: Cadieux
authors: Jeffrey C
authors: JC
authors: Howard
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D007778:Lactobacillus / Q000502:physiology*; D008297:Male; D019736:Prostheses and Implants / Q000009:adverse effects*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013203:Staphylococcal Infections / Q000517:prevention & control*; D013211:Staphylococcus aureus / Q000302:isolation & purification*