Spontaneous regression of retinal astrocytic hamartoma in a patient with tuberous sclerosis.
OBJECTIVE
To report the complete regression of a retinal astrocytic hamartoma in conjunction with tuberous sclerosis.


METHODS
Observational case report.


METHODS
A 12-year-old boy with tuberous sclerosis, diagnosed early in life, was found to have a retinal astrocytic hamartoma in his left eye. He had bilateral optic atrophy because of long-standing increased intracranial pressure due to a cerebral giant cell astrocytoma. He was followed on a yearly basis with fundus photography and fluorescein angiography.


RESULTS
At the time of initial presentation, the minimally elevated intraretinal tumor measured 2 x 1.5 mm. A year later, the same tumor measured 1.5 x 1 mm. Two years after initial presentation, the tumor totally disappeared.


CONCLUSIONS
This patient has demonstrated that retinal astrocytic hamartoma may undergo spontaneous regression.
Kiratli
Hayyam
H
Ocular Oncology Service, Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey. hkiratli@hacettepe.edu.tr
Bilgiç
Sevgül
S
D001253:Astrocytes / Q000473:pathology; D002648:Child; D005451:Fluorescein Angiography; D006222:Hamartoma / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009896:Optic Atrophy / Q000473:pathology; D010781:Photography; D012075:Remission, Spontaneous; D012164:Retinal Diseases / Q000175:diagnosis / Q000503:physiopathology*; D012189:Retrospective Studies; D014402:Tuberous Sclerosis / Q000503:physiopathology*