3-Deoxy-1beta,20-dihydroxyecdysone from the leaves of Diploclisia glaucescens.
Chemical investigation of methanol extract of the leaves of Diploclisia glaucescens of the family Menispermaceae furnished a new ecdysteroid, 3-deoxy-1beta,20-dihydroxyecdysone. The structure of the new ecdysteroid was established on detailed analysis of spectral data. The 3-deoxy ecdysteroid showed 40% potency of 20-hydroxyecdysone in the spiracle index assay using the fourth instar larvae of the silkworm Bombyx mori.
Jayasinghe
Lalith
L
Institute of Fundamental Studies, Hantana Road, Kandy, Sri Lanka. lalith@ifs.ac.lk
Jayasooriya
Champika P
CP
Oyama
Kiyoshi
K
Fujimoto
Yoshinori
Y
D004440:Ecdysone / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification; D004441:Ecdysterone / Q000737:chemistry; D029583:Menispermaceae / Q000737:chemistry*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry*
C467538:3-deoxy-1,20-dihydroxyecdysone; D004440:Ecdysone; D004441:Ecdysterone