title: Statistical analysis of the relationship between translation initiation AUG context and gene expression level in humans.
abstract: The preference for the optimal nucleotide of the mammalian translation initiation AUG context [GCCGCC(A/G)CCaugG] is generally more pronounced in the highly expressed genes than in the transcription factor genes at the -9 through -1 positions in humans. The influence of amino acid preference on the nucleotide choice at the +4 position was also examined.
authors: The Kansai Electric Power Co, Technical Research Center, Amagasaki, Hyogo, Japan. K448482@kepco.co.jp
authors: Hitoshi
authors: H
authors: Miyasaka
authors: Shozo
authors: S
authors: Kanai
authors: Satoshi
authors: S
authors: Tanaka
authors: Hideo
authors: H
authors: Akiyama
authors: Masahiko
authors: M
authors: Hirano
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D005786:Gene Expression Regulation / Q000235:genetics*; D006801:Humans; D010442:Peptide Chain Initiation, Translational / Q000235:genetics*; D014176:Protein Biosynthesis / Q000235:genetics*; D012269:Ribosomal Proteins / Q000737:chemistry / Q000235:genetics; D014157:Transcription Factors
chemical_list: D000596:Amino Acids; D012269:Ribosomal Proteins; D014157:Transcription Factors