Therapy for recurrent respiratory papillomatosis.
Human papillomaviruses types 6 or 11 are aetiological agents of recurrent respiratory papillomatosis, a disease characterized by benign exophytic tumours usually on the vocal cords. Surgery debulks the tumours, but these growths generally recur at regular intervals. Adjunct medical treatments, aimed at containing the virus and growth of tumours, include indole-3-carbinol or its dimer diindolylmethane, interferon, photodynamic therapy and others. Preventive and therapeutic vaccines hold promise for eliminating the virus.
Auborn
Karen J
KJ
Department of Otolaryngology, Long Island Jewish Medical Center, Albert Einstein College of Medicine, New Hyde Park, NY, USA. kauborn@nshs.edu
D000077404:Cidofovir; D003596:Cytosine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D007822:Laryngeal Neoplasms / Q000628:therapy*; D008175:Lung Neoplasms / Q000628:therapy*; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D063065:Organophosphonates; D009943:Organophosphorus Compounds / Q000627:therapeutic use; D010212:Papilloma / Q000628:therapy*; D027383:Papillomaviridae; D010778:Photochemotherapy; D014827:Vocal Cords
D063065:Organophosphonates; D009943:Organophosphorus Compounds; D003596:Cytosine; D007372:Interferons; D000077404:Cidofovir