title: Genealogical trees, coalescent theory and the analysis of genetic polymorphisms.
abstract: Improvements in genotyping technologies have led to the increased use of genetic polymorphism for inference about population phenomena, such as migration and selection. Such inference presents a challenge, because polymorphism data reflect a unique, complex, non-repeatable evolutionary history. Traditional analysis methods do not take this into account. A stochastic process known as the 'coalescent' presents a coherent statistical framework for analysis of genetic polymorphisms.
authors: Program in Molecular and Computational Biology, University of Southern California, 835 West 37th Street, SHS172, Los Angeles, California 90089-1340, USA.
authors: Noah A
authors: NA
authors: Rosenberg
authors: Magnus
authors: M
authors: Nordborg
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D005828:Genetics, Population; D006801:Humans; D010375:Pedigree; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic; D013269:Stochastic Processes