[Brown fat tissue in humans].
Brown adipose tissue (BAT) is universally present in mammals. Thermal production in such tissue is physiologically important for maintaining temperature homeostasis and regulation of body mass in small-size homoiotherms. At present it is clearly established that unlike other large mammals, brown adipose in man and primates is retained throughout the whole postnatal othogenesis. Therefore, BAT appears as a possible effector of pharmacogenetic protection from human excessive adiposis. Systematic reserach of various functioning aspects of this unique organ of mammals were started abroad as early as 1960-es, and are actively developing at present. Domestic research of energy circulation physiology and of thermoregulation developed mostly outside the brown adipose tissue. Therefore, the principal objective of this publication is to draw attention of experimental and clinical researches to an intriguing aspect of the issue of energy circulation in humans--the issue of brown adipose functioning.
Medvedev
L N
LN
Pedagogical University, Krasnoyarsk.
Elsukova
E I
EI
D017667:Adipocytes / Q000378:metabolism; D002001:Adipose Tissue, Brown / Q000033:anatomy & histology / Q000378:metabolism / Q000502:physiology*; D000310:Adrenal Gland Neoplasms / Q000378:metabolism; D000818:Animals; D001831:Body Temperature; D002352:Carrier Proteins / Q000378:metabolism; D003480:Cushing Syndrome / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism; D004734:Energy Metabolism; D006801:Humans; D007231:Infant, Newborn; D007473:Ion Channels; D008565:Membrane Proteins / Q000378:metabolism; D024101:Mitochondrial Proteins; D010673:Pheochromocytoma / Q000378:metabolism; D011943:Receptors, Adrenergic, beta / Q000502:physiology; D013398:Sudden Infant Death; D013564:Sympathetic Nervous System / Q000502:physiology; D022722:Thermogenesis / Q000502:physiology; D000071256:Uncoupling Protein 1
D002352:Carrier Proteins; D007473:Ion Channels; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D011943:Receptors, Adrenergic, beta; D000071256:Uncoupling Protein 1