Birth of a healthy baby after transfer of embryos that were cryopreserved for 8.9 years.
OBJECTIVE
To report successful pregnancy from embryos that had been cryopreserved for 8.9 years.


METHODS
Case report.


METHODS
Fertility clinic of the University of Buenos Aires School of Medicine.


METHODS
A 43-year-old woman with ovarian failure and a 45-year-old man with nonobstructive azoospermia underwent embryo donation.I NTERVENTION(S): Five embryos that had been cryopreserved and stored since 1989 were thawed in 1998 and donated to an infertile couple. Endometrial preparation was performed with 17beta-estradiol and progesterone. The four embryos with better morphologic characteristics were transferred into the uterus.


METHODS
Post-thaw embryo survival, pregnancy, and birth.


RESULTS
Embryo survival was satisfactory as assessed by morphology. Pregnancy was confirmed by ultrasonography. A healthy baby weighing 2120 g was delivered by cesarean section at 36 weeks.


CONCLUSIONS
Human 8-cell embryos may be viable after extended storage and can result in successful pregnancy.
Quintans
Carlos J
CJ
Halitus Instituto Médico Afiliado a la Facultad de Medicina de la Universidad de Buenos Aires, Buenos Aires, Argentina. cquintans@halitus.com
Donaldson
Mónica J
MJ
Bertolino
María Victoria
MV
Godoy
Hugo
H
Pasqualini
R Sergio
RS
D000328:Adult; D002585:Cesarean Section; D015925:Cryopreservation; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000502:physiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D036801:Parturition; D011247:Pregnancy; D013997:Time Factors; D016216:Ultrasonography, Prenatal