title: Ambulatory blood pressure monitoring in Uygur centenarians.
abstract: Cross-sectional surveillance was carried out in long-lived Uygur in China to investigate blood pressure (BP) and pulse rate (PR) variation in centenarians. The study group comprised 33 centenarians (age > or = 100 years), 103 longevous subjects (age 90-99 years) and 100 elderly (age 65-70 years) subjects. Office BP was measured, and 24-h noninvasive ambulatory blood pressure monitoring (ABPM) was performed. The office BP was higher and hypertension occurred more frequently in the centenarians than in either the longevous or elderly subjects. Mean 24-h systolic and diastolic BP was higher in the centenarians than in the other 2 groups. However, mean 24-h PR did not differ between them. Day-night differences in systolic BP decreased, and the non-dipper-type BP pattern was common in the centenarians (79.1% vs 68% and 63.6% in longevous and elderly subjects, respectively). Circadian BP was characterized by 3 peaks in longevous subjects and multiple peaks in centenarians. Morning rising and nocturnal dipping of BP were observed in both longevous and elderly subjects. In conclusion, BP in longevous and elderly Uygur was characterized by circadian rhythmicity, but the nocturnal fall in BP was not seen in centenarians. Differences in day-night BP and circadian rhythmicity may decrease with advancing age, especially in centenarians.
authors: 2nd Department of Medicine, Itabashi Hospital, Nihon University School of Medicine, Tokyo, Japan.
authors: Medet
authors: M
authors: Jumabay
authors: Yukio
authors: Y
authors: Ozawa
authors: Hiroshi
authors: H
authors: Kawamura
authors: Satoshi
authors: S
authors: Saito
authors: Yoichi
authors: Y
authors: Izumi
authors: Hiromi
authors: H
authors: Mitsubayashi
authors: Yuji
authors: Y
authors: Kasamaki
authors: Tomohiro
authors: T
authors: Nakayama
authors: Masum
authors: M
authors: Mahumut
authors: Zuheng
authors: Z
authors: Cheng
authors: Shezhen
authors: S
authors: Wang
authors: Katsuo
authors: K
authors: Kanmatsuse
mesh_terms: D000368:Aged; D000369:Aged, 80 and over / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002681:China; D002940:Circadian Rhythm / Q000502:physiology*; D003430:Cross-Sectional Studies; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male