Information processing in bacterial chemotaxis.
Motile bacteria respond to attractants and repellents in their environment by changing their movement. Stock et al. describe the similarities of the bacterial chemotaxis signaling system to eukaryotic signaling cascades. Also included is a discussion of how the ordered signaling complex of the receptor, the kinase CheA, and the kinase regulator CheW can be thought of as a primitive "probrain" to allow the integration of signals to produce the optimal cellular response.
Stock
Jeffry B
JB
Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. jstock@princeton.edu
Levit
Mikhail N
MN
Wolanin
Peter M
PM
D000818:Animals; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D002633:Chemotaxis / Q000502:physiology*; D004926:Escherichia coli / Q000502:physiology; D029968:Escherichia coli Proteins; D000071677:Histidine Kinase; D008565:Membrane Proteins / Q000502:physiology; D000072236:Methyl-Accepting Chemotaxis Proteins; D015398:Signal Transduction / Q000502:physiology
D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins; D000071677:Histidine Kinase; C000607608:cheA protein, E coli