title: Cold denaturation of proteins under high pressure.
abstract: The advantageous usage of the high pressure technique in studies of cold denaturation of proteins is reviewed, with a brief explanation of the theoretical background of this universal phenomenon. Various experimental results are presented and discussed, explaining the plausible image of the cold denatured state of proteins. In order to understand more clearly this phenomenon and protein structure transition in general, several studies on model polymer systems are also reviewed.
authors: Laboratory for Biopolymer Chemistry, Department of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo, Kyoto, Japan. kunugi@ipc.kit.ac.jp
authors: Shigeru
authors: S
authors: Kunugi
authors: Naoki
authors: N
authors: Tanaka
mesh_terms: D000818:Animals; D003080:Cold Temperature; D008958:Models, Molecular; D011108:Polymers; D011312:Pressure; D011489:Protein Denaturation; D011506:Proteins / Q000737:chemistry*
chemical_list: D011108:Polymers; D011506:Proteins