title: Total knee replacement in haemophilia.
abstract: We believe that total knee replacement (TKR) is a safe and effective procedure for the management of haemophiliac joint arthropathy; however, the increased risk of infection and non-infective complications remain a cause for concern. TKR in haemophilic patients carries with it an increased risk of post-operative infection in comparison to non-haemophiliac patients. Those patients at particular risk are the HIV-positive haemophiliac patients whose CD4 count is less than 200 cells mm-3. The latest techniques have gone a long way to reducing the complication rate and to achieving results that match those of a similar non-haemophiliac population.
authors: Department of Orthopaedics, Royal Free Hospital School of Medicine, London, UK.
authors: N J
authors: NJ
authors: Goddard
authors: E C
authors: EC
authors: Rodriguez-Merchan
authors: J D
authors: JD
authors: Wiedel
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects / Q000706:statistics & numerical data; D006395:Hemarthrosis / Q000517:prevention & control / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications* / Q000628:therapy / Q000821:virology; D006801:Humans; D016896:Treatment Outcome