title: Primary breast lymphoma successfully treated with combination therapy including local radiation therapy: a report of two cases.
abstract: Recently, a combination of local irradiation and chemotherapy has been suggested as a standardized treatment for localized lymphoma. However, it has been difficult to establish a standard treatment for localized primary breast lymphoma simply because of its rarity. We report two cases of primary breast lymphoma successfully treated with a combination therapy including local radiation therapy. A 46-year-old woman with stage I primary breast lymphoma was irradiated with 30 Gy to the involved breast by 4 MV X-rays and 9 Gy to the involved field by electron beam after tumorectomy. Then three cycles of CHOP therapy were performed. She has been well and has shown no evidence of disease for 58 months. A 72-year-old woman with stage II primary breast lymphoma was treated with three cycles of CHOP therapy followed by irradiation with 40 Gy per breast by 4 MV X-rays. She is well and has been disease-free for 49 months. We suggest that a combination of local irradiation and short course of chemotherapy can be useful in the treatment of primary breast lymphoma.
authors: Department of Radiology, Maebashi Red Cross Hospital, Japan.
authors: Yoshiyuki
authors: Y
authors: Suzuki
authors: Jun
authors: J
authors: Ito
authors: Masatoshi
authors: M
authors: Hasegawa
authors: Susumu
authors: S
authors: Katano
authors: Junichi
authors: J
authors: Saito
authors: Hideaki
authors: H
authors: Ito
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000188:drug therapy / Q000532:radiotherapy*; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D011882:Radiotherapy, High-Energy; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone