[Blood infrared spectrometry in progressive myodystrophy].
Twenty four patients with various progressive myodistrophy (PMD) types have been examined. Initial and follow-up blood counts, using infrared spectrometry, were carried out. All the patients had phospholipid dysbolism. Its level positively correlated with myodistrophy severity. Phospholipid level decrease was associated with membrane permeability increase. The authors consider phospholipid dysfunction as one of the key PMD pathogenetic mechanisms. Blood infrared spectrometry is recommended for PMD severity determination, in diagnosis and therapy which is pathogenetically substantiated.
Gerasimova
M M
MM
Dudkina
N A
NA
Kargapolov
A V
AV
D000328:Adult; D002463:Cell Membrane Permeability; D018450:Disease Progression; D004912:Erythrocytes / Q000737:chemistry*; D005260:Female; D006801:Humans; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000378:metabolism; D009136:Muscular Dystrophies / Q000097:blood* / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D012720:Severity of Illness Index; D013055:Spectrophotometry, Infrared / Q000379:methods
D008563:Membrane Lipids; D010743:Phospholipids