title: The effects of osmotic and hydrostatic pressures on macromolecular systems.
abstract: Osmotic pressure and hydrostatic pressure can be used effectively to probe the behavior of biologically important macromolecules and their complexes. Using the two techniques requires a theoretical framework as well as knowledge of the more common pitfalls. Both are discussed in this review in the context of several examples.
authors: Enzyme Research Group, Department of Biology, Concordia University, Montreal, QC, Canada. krnbltt@vax2.concordia.ca
authors: Jack A
authors: JA
authors: Kornblatt
authors: M Judith
authors: MJ
authors: Kornblatt
mesh_terms: D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry*; D003576:Electron Transport Complex IV / Q000737:chemistry*; D006801:Humans; D006874:Hydrostatic Pressure; D046911:Macromolecular Substances; D009696:Nucleic Acids / Q000737:chemistry; D009997:Osmotic Pressure; D010751:Phosphopyruvate Hydratase / Q000737:chemistry*; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*
chemical_list: D046911:Macromolecular Substances; D009696:Nucleic Acids; D011506:Proteins; D003577:Cytochrome P-450 Enzyme System; D003576:Electron Transport Complex IV; D010751:Phosphopyruvate Hydratase