[Analyzing partial nucleotide and amino acid sequences of Chinese TTV isolates].
BACKGROUND
To investigate the prevalence of transfusion transmitted virus (TTV) and its sequence characterization in China.


METHODS
TTV DNA was amplified by Semi-Nested-PCR, and the positive products were sequenced directly.


RESULTS
The homology of partial nucleotide and amino acid sequences of 7 Chinese TTV isolates were 64.7%-98.4% and 62.7%-96.4% respectively when compared with Japanese isolate. Among 7 Chinese TTV isolates, the homology of partial nucleotide and amino acid sequences were 63.5%-98.4% and 60.2%-96.4% respectively. They differently belong to two genotypes and two subgenotypes.


CONCLUSIONS
There exists TTV in China, and there might be several genotypes of Chinese TTV isolates.
Fang
F
F
Department of Clinical Laboratory, Eastern Hepatobiliary Hospital, The Second Military Medical University, Shanghai 200438, China.
Wang
H
H
Wang
A
A
D000595:Amino Acid Sequence; D001483:Base Sequence; D005838:Genotype; D006801:Humans; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D022783:Torque teno virus / Q000737:chemistry / Q000235:genetics*