Impact of repeated surgical procedures on the incidence and prevalence of latex allergy: a prospective study of 1263 children.
Assessment with questionnaire, skin tests, and immunoglobulin E measurements showed 6 (0.5%) of 1263 children having elective surgery had latex allergy; 50 (4%) others were latex-sensitized. Any previous operation increased the odds of latex sensitization by 13 times; multiple operations had a less marked effect. All children having surgery may need primary prophylaxis for latex.
Hourihane
Jonathan O'B
JO
Immunobiology Unit and Paediatric Epidemiology and Biostatistics Unit, Institute of Child Health, and Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.
Allard
Jonathan M
JM
Wade
Angela M
AM
McEwan
Angus I
AI
Strobel
Stephan
S
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000918:Antibody Specificity / Q000276:immunology; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology* / Q000276:immunology / Q000601:surgery*; D007114:Immunization; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D020315:Latex Hypersensitivity / Q000453:epidemiology* / Q000276:immunology / Q000601:surgery*; D016015:Logistic Models; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012086:Reoperation; D016896:Treatment Outcome
D007073:Immunoglobulin E