title: High dose rate endovascular brachytherapy in aorto-iliac lesion for the prevention of restenosis.
abstract: This study examined the applicability of endovascular brachytherapy to larger del arteries such as the abdominal aorta and iliac artery. Endovascular brachytherapy using an Ir-192 HDR source was administered 11 times to nine patients who had undergone percutaneous transluminal angioplasty (PTA) between 1995 and 1999. The follow-up lasted 13 to 55 months after treatment (median, 24 months). Eight of the 11 lesions have been controlled so far. Although one case developed thrombus inside the stent five months later, recanalization was achieved by means of retreatment. One patient who underwent low-dose irradiation (6 Gy) without stent implantation showed restenosis five months after treatment. We used a centering catheter that did not block the blood stream for exact centering of the radiation source in larger vessels such as the abdominal aorta. Although endovascular brachytherapy is a promising and safe procedure, careful follow-up is needed to detect untoward reactions such as thrombosis.
authors: Department of Radiology, Toyonaka Municipal Hospital, Japan.
authors: Hideya
authors: H
authors: Yamazaki
authors: Kaname
authors: K
authors: Tomoda
authors: Hiroya
authors: H
authors: Shiomi
authors: Munehiro
authors: M
authors: Maeda
authors: Shuji
authors: S
authors: Kawata
authors: Atsuya
authors: A
authors: Okada
authors: Takamichi
authors: T
authors: Murakami
authors: Hironobu
authors: H
authors: Nakamura
authors: Eiichi
authors: E
authors: Tanaka
authors: Takehiro
authors: T
authors: Inoue
authors: Toshihiko
authors: T
authors: Inoue
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001018:Aortic Diseases / Q000532:radiotherapy*; D001157:Arterial Occlusive Diseases / Q000532:radiotherapy*; D001918:Brachytherapy / Q000379:methods*; D003251:Constriction, Pathologic / Q000517:prevention & control; D006801:Humans; D006965:Hyperplasia / Q000517:prevention & control; D007083:Iliac Artery; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D008297:Male; D017539:Tunica Intima
chemical_list: D007496:Iridium Radioisotopes