title: Unique management of stage 4S neuroblastoma complicated by massive hepatomegaly: case report and review of the literature.
abstract: Stage 4S neuroblastoma is an unusual malignancy that has an excellent prognosis, except in young infants. A 2-month-old with 4S neuroblastoma complicated by massive hepatomegaly, managed by abdominal decompression surgery and a negative-pressure dressing system is presented. Diffuse alveolar hemorrhage also developed, which was treated with high-dose corticosteroids.
authors: Department of Pediatrics, Tripler Army Medical Center, Hawaii, USA. roberste@ohsu.edu
authors: Stephen
authors: S
authors: Roberts
authors: Kevin
authors: K
authors: Creamer
authors: Braden
authors: B
authors: Shoupe
authors: Yolanda
authors: Y
authors: Flores
authors: Daniel
authors: D
authors: Robie
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery*; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000310:Adrenal Gland Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001942:Breast Feeding; D016190:Carboplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004750:Enteral Nutrition; D005047:Etoposide / Q000008:administration & dosage; D006470:Hemorrhage / Q000209:etiology; D006529:Hepatomegaly / Q000209:etiology*; D006801:Humans; D007223:Infant; D007813:Laparotomy / Q000379:methods*; D008113:Liver Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D008171:Lung Diseases / Q000209:etiology / Q000628:therapy; D008297:Male; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000150:complications / Q000188:drug therapy / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D009779:Occlusive Dressings; D010198:Pancytopenia / Q000209:etiology; D010289:Parenteral Nutrition, Total; D011175:Positive-Pressure Respiration; D011183:Postoperative Complications / Q000188:drug therapy; D018805:Sepsis / Q000150:complications; D013526:Surgical Mesh; D014618:Vacuum
chemical_list: D000305:Adrenal Cortex Hormones; D005047:Etoposide; D016190:Carboplatin