Outbreak of Empedobacter brevis endophthalmitis after cataract extraction.
BACKGROUND
We present a series of patients who were operated upon on the same day by the same surgeon. All of those patients developed postoperative endophthalmitis due to Empedobacter brevis - a bacterium hitherto unknown in ophthalmologic literature.


METHODS
Twelve patients were referred because of endophthalmitis after cataract extraction. The patients' files were studied and the intraoperative and postoperative outcome was analysed.


RESULTS
Twelve patients (five male, seven female, mean age 75 years) presented 1-6 days after uncomplicated cataract extraction. Although some suffered from medical or ophthalmological diseases there was no association with the severity of the endophthalmitis. Eleven patients required vitrectomy, seven as primary procedure, one primary with extraction of the lens and three secondary after anterior chamber lavage and intravitreal antibiotics. In three cases vitrectomy had to be repeated together with extraction of the intraocular lens. There were two postoperative retinal detachments that required silicon oil and in one case an encircling band. Mean visual acuity rose from 0.02 to 0.47 by 9 months after operation. Empedobacter brevis was found in the anterior chamber and in the vitreous in all except one patient.


CONCLUSIONS
In high-volume cataract surgery endemic endophthalmitis is always possible. Sources of infection may be anything from the lens to the sterilisation process, the latter being the primary suspect in our series. Prompt, adequate and (if necessary) aggressive treatment by vitreous surgery may lead to favourable results.
Janknecht
P
P
Department of Ophthalmology, Albert-Ludwigs University of Freiburg, Killianstrasse 9, 79106 Freiburg, Germany.
Schneider
C M
CM
Ness
T
T
D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002387:Cataract Extraction; D003131:Combined Modality Therapy; D004196:Disease Outbreaks; D009877:Endophthalmitis / Q000453:epidemiology* / Q000382:microbiology / Q000628:therapy; D015818:Eye Infections, Bacterial / Q000453:epidemiology* / Q000382:microbiology / Q000628:therapy; D005260:Female; D005417:Flavobacterium / Q000302:isolation & purification*; D005858:Germany / Q000453:epidemiology; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000382:microbiology / Q000628:therapy; D012086:Reoperation; D014821:Vitrectomy; D014822:Vitreous Body / Q000382:microbiology
D000900:Anti-Bacterial Agents