title: Carbamazepine-induced acute granulomatous interstitial nephritis.
abstract: A 79-year-old man, newly started on carbamazepine, presented with rash, eosinophilia and liver dysfunction progressing to acute renal failure despite discontinuation of the anti-epileptic agent. Percutaneous renal biopsy revealed acute granulomatous interstitial nephritis, which responded successfully to high-dose oral steroid therapy.
authors: Department of Renal Medicine, Hope Hospital, Salford, UK. jan.hegarty@ticketbox.net
authors: J
authors: J
authors: Hegarty
authors: M
authors: M
authors: Picton
authors: G
authors: G
authors: Agarwal
authors: A
authors: A
authors: Pramanik
authors: P A
authors: PA
authors: Kalra
mesh_terms: D000208:Acute Disease; D000368:Aged; D000927:Anticonvulsants / Q000009:adverse effects*; D001706:Biopsy; D002220:Carbamazepine / Q000009:adverse effects*; D003875:Drug Eruptions / Q000175:diagnosis; D006099:Granuloma / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000473:pathology; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced*
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine