title: First-trimester sonographic diagnosis of distal urethral atresia with megalourethra in VACTERL association.
abstract: Congenital megalourethra is a rare disorder. We present an early case diagnosed in the first trimester. Prenatal ultrasound showed a megalourethra with a normal fetal bladder, hyperechogenic cystic right kidney and single umbilical artery. After termination of pregnancy, necropsy confirmed all sonographic findings and revealed other malformations (spina bifida occulta, anal atresia, tracheo-oesophageal fistula, brachydactylia) resulting in the diagnosis of VACTERL association. The prenatal diagnostician should seek histological examination firstly to confirm his findings and secondly to avoid missing associations and inherited malformations.
authors: Division of Prenatal Medicine, Department of Obstetrics and Gynecology, Medical University of Lübeck, Germany. DrMartinKrapp@web.de
authors: Martin
authors: M
authors: Krapp
authors: Annegret
authors: A
authors: Geipel
authors: Ute
authors: U
authors: Germer
authors: Manuela
authors: M
authors: Krokowski
authors: Ulrich
authors: U
authors: Gembruch
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000473:pathology; D000025:Abortion, Eugenic; D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D005385:Fingers / Q000002:abnormalities; D006801:Humans; D008297:Male; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016135:Spinal Dysraphism; D014138:Tracheoesophageal Fistula / Q000151:congenital; D016216:Ultrasonography, Prenatal; D014521:Urethra / Q000002:abnormalities* / Q000000981:diagnostic imaging