[Risks in hysteroscopy in patients with endometrial carcinoma--a prospective clinical study].
OBJECTIVE
The evaluation of the risk of hysteroscopy (HSC) in patients with endometrial carcinoma with regard to the dissemination of disease and the deterioration of its prognosis.


METHODS
A prospective multicentric study.


METHODS
Department of Obstetrics and Gynaecology and Institute of Pathology of the Palacky Univerzity Medical School and University Hospital, Olomouc; Obstetrical and Gynecological Departments of collaborating hospitals.


METHODS
Two groups of patients with endometrial carcinoma were compared on the basis of cytological examinations from the peritoneal cavity. The study group (n = 156) consisted of patients whose diagnosis was made on the base of HSC and targeted biopsy. The control group (n = 71) included patients with the classical D&C. Both groups were comparable as to the distribution of clinical stages of the disease (P < 0.05). Cytological examinations were performed from the fluid obtained by the puncture of the cul de sac at the end of the HSC procedure and from the peritoneal lavage at the beginning of the following operation. Results of both groups were compared and statistically evaluated.


CONCLUSIONS
The comparison of the cytological findings from the punctures of the cul de sac after the HSC and from the lavages at the following operation did not show an increased penetration of malignant cells from the uterus into the abdominal cavity. Similarly, the comparison of cytological findings from the peritoneal lavages after HSC and probatory curettage did not show a statistically significant difference between both groups. We assume that HSC does not increase the risk of dissemination of tumour cells into the peritoneal cavity and does not deteriorate the prognosis of the disease.
Kudela
M
M
Gynekologicko-porodnická klinika, UP LF a FN Olomouc.
Pilka
R
R
Dzvincuk
P
P
Lubuský
D
D
Dusková
M
M
D002277:Carcinoma / Q000175:diagnosis*; D003581:Cytodiagnosis; D004107:Dilatation and Curettage; D016889:Endometrial Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000009:adverse effects*; D009366:Neoplasm Seeding; D011446:Prospective Studies; D012307:Risk Factors