Twelve cases of placental chorioangioma. Pregnancy outcome and clinical significance.
BACKGROUND
To determine perinatal complications and pregnancy outcome in 12 women with chorioangioma of placenta.


METHODS
During the period between January 1986 and December 1997, 12 women with histologic diagnosis of chorioangioma of placenta who delivered in our institution were studied. Case-control study was designed. Sixty women with histologic examination of the placenta without chorioangioma were randomly identified as control group matched for maternal age and parity. Statistical analyses included t-test, Chi-square test and Fisher's exact test when appropriate.


RESULTS
Nine cases (75%) were diagnosed postnatal. The mean gestational age was significantly lower and preterm delivery rate was significantly higher among the chorioangioma group (34 vs. 38.8 weeks P<0.0001; 66% vs. 10%; P<0.001 respectively).


CONCLUSIONS
Chorioangioma of the placenta, in a high risk population, although small, is associated with significantly higher risk for preterm delivery. This emphasizes the need for pathologic examination of all placentas of patients with preterm delivery
Bashiri
A
A
Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Furman
B
B
Erez
O
O
Wiznitzer
A
A
Holcberg
G
G
Mazor
M
M
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006391:Hemangioma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007752:Obstetric Labor, Premature / Q000209:etiology; D010922:Placenta Diseases / Q000150:complications* / Q000175:diagnosis; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis; D011256:Pregnancy Outcome