title: Constituents of Burasaïa madagascarensis: a new clerodane-type diterpene.
abstract: From an ethanol extract of the stems of Burasaïa madagascarensis Thouars (Menispermaceae) were isolated N-acetylnornuciferine and two clerodane-type diterpenes, one of them, epicordatine, being new. The structures were established by the interpretation of the spectral data. All the described compounds exhibited weak antimalarial activity.
authors: Lengo
authors: L
authors: Mambu
authors: Voahangy
authors: V
authors: Ramanandraibe
authors: Marie Thérèse
authors: MT
authors: Martin
authors: Alain
authors: A
authors: Blond
authors: Philippe
authors: P
authors: Grellier
authors: François
authors: F
authors: Frappier
mesh_terms: D000818:Animals; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D045785:Diterpenes, Clerodane; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D019271:Hypoxanthine / Q000493:pharmacokinetics; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000378:metabolism; D014316:Tritium
chemical_list: D004224:Diterpenes; D045785:Diterpenes, Clerodane; D005663:Furans; D010936:Plant Extracts; C459632:epicordatine; C459633:penianthic acid, methyl ester; D014316:Tritium; D019271:Hypoxanthine