title: Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A.
abstract: Two enantiomerically pure hydroxymethyl substituted cyclopentene nucleoside analogues (42 and 53) related to carbovir and neplanocin A, respectively, were prepared from the chiral pool of iridoid glucosides. In addition two saturated hydroxymethylated analogues (44 and 45) were obtained from a protected intermediate.
authors: Department of Organic Chemistry, Technical University of Denmark, Lyngby.
authors: Henrik
authors: H
authors: Franzyk
authors: Søren Rosendal
authors: SR
authors: Jensen
authors: Carl Erik
authors: CE
authors: Olsen
authors: Jon Holbech
authors: JH
authors: Rasmussen
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000737:chemistry*; D015224:Dideoxynucleosides / Q000737:chemistry*; D009705:Nucleosides / Q000138:chemical synthesis*
chemical_list: D015224:Dideoxynucleosides; D009705:Nucleosides; C057503:carbovir; C031096:neplanocin A; D000241:Adenosine