Solitary fibrous tumour in the deep soft tissue of the neck in a Chinese man.
Originally described in the pleura, solitary fibrous tumour (SFT) is now reported in a variety of extrapleural sites. However, description of SFT in the deep soft tissue of the neck is very rare. In this report, we document the neoplasm, deep to the right platsyma muscle but superficial to the deep fascia just above the clavicle, in an otherwise well 50-year-old Chinese man. Histological examination of the excised specimen disclosed spindle-shaped cells disposed in short fascicles as well as randomly in association with areas of varying cellularity, keloidal hyalinisation of the stroma and haemangiopericytoma-like vessels. The tumour cells were CD34-, bcl-2- and CD99-positive. Since histological features may not accurately predict the biological behaviour of this tumour, careful long-term follow-up is advocated.
Goh
Seng Geok Nicholas
SG
Department of Pathology, Singapore General Hospital.
Chuah
Khoon Leong
KL
Sim
Chee Seng
CS
Ong
Beng Hock
BH
D000071443:12E7 Antigen; D015703:Antigens, CD / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D015815:Cell Adhesion Molecules / Q000032:analysis; D006258:Head and Neck Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D051917:Leukosialin; D008297:Male; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D012795:Sialoglycoproteins / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
D000071443:12E7 Antigen; D015703:Antigens, CD; D014408:Biomarkers, Tumor; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; D051917:Leukosialin; D019253:Proto-Oncogene Proteins c-bcl-2; C465014:SPN protein, human; D012795:Sialoglycoproteins