title: Antibiotic resistance and sero-groups of shigella among paediatric out-patients in southwest Ethiopia.
abstract: OBJECTIVE
  To determine the prevalence of Shigella sero-groups and resistance pattern of isolates to commonly used antibiotics in Jimma.
  
  
  METHODS
  Cross-sectional survey.
  
  
  METHODS
  The study was conducted in Jimma, southwest Ethiopia.
  
  
  METHODS
  A total of 384 paediatric out-patients with diarrhoea aged 14 years and below were studied.
  
  
  METHODS
  Stool specimens were collected from children presenting with diarrhoea using Cary-Blair transport medium and buffer treated swabs from Jimma hospital and Jimma health centre. Isolation, biochemical characterisation, sero-grouping and antibiotic sensitivity testing were performed according to standard methodology in the Microbiology laboratory of Jimma University.
  
  
  RESULTS
  Out of the 77 Shigella strains isolated, sero-group A comprised 29.9%, B 40.3%, C 19.5% and D 10.4%. Among all Shigella sero-groups, highest resistance was encountered to tetracycline (63.6%), ampicillin (70.1%), cephalothin (57.1%), trimethoprim-sulphamethoxazole (32.5%) and chloramphenicol (40.3%) whileleast resistance was observed to gentamicin (1.3%), polymyxin B (3.9%) and nalidixic acid (6.5%).
  
  
  CONCLUSIONS
  Gentamicin, polymyxin B and nalidixic acid were found to be the drugs of choice for cases related with shigellosis.
authors: Department of Medical Microbiology and Parasitology, Jimma University, Ethiopia.
authors: A
authors: A
authors: Mache
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D024881:Drug Resistance, Bacterial; D004405:Dysentery, Bacillary / Q000453:epidemiology* / Q000382:microbiology; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010045:Outpatients; D015995:Prevalence; D012703:Serotyping; D012760:Shigella / Q000145:classification* / Q000187:drug effects