title: Extension of breast cancer: comparison of CT and MRI.
abstract: OBJECTIVE
  To compare three-dimensional (3D) helical CT with 3D MRI in the evaluation of intraductal spread of breast cancer.
  
  
  METHODS
  Fifty patients with breast cancer were examined. Tumor size ranged from Tis to T2. The whole breast was scanned by both breath-holding helical CT and MRI with contrast media. Linear or segmental enhancement, and spotty enhancement around the main tumor were considered to indicate ductal carcinoma in situ (DCIS) or ductal spread. These findings were compared with thin section histopathologic data.
  
  
  RESULTS
  Seventeen of 35 patients had intraductal spread with invasive cancer and 15 patients had DCIS. The sensitivity, specificity, and accuracy of 3D CT in detecting intraductal spread or DCIS were 71.9%, 83.3%, and 76.0%, respectively, and those of 3D MRI were 87.5%, 61.1%, and 78.0%. Overestimations numbered three (6.0%) on CT and seven (14.0%) on MRI, and underestimations numbered nine (18.0%) on CT and four (8.0%) on MRI.
  
  
  CONCLUSIONS
  3D helical CT can provide good information about the spread of breast cancer and could be an alternative to 3D MRI for preoperative examination of breast cancer.
authors: Department of Radiology, Miyazaki Medical College, Kiyotake, Japan.
authors: Hiroshi
authors: H
authors: Nakahara
authors: Kiyoshi
authors: K
authors: Namba
authors: Hideyuki
authors: H
authors: Wakamatsu
authors: Ryoji
authors: R
authors: Watanabe
authors: Hidemi
authors: H
authors: Furusawa
authors: Mitsunori
authors: M
authors: Shirouzu
authors: Takafumi
authors: T
authors: Matsu
authors: Chiaki
authors: C
authors: Tanaka
authors: Futoshi
authors: F
authors: Akiyama
authors: Hiromi
authors: H
authors: Ifuku
authors: Mayumi
authors: M
authors: Nakahara
authors: Shozo
authors: S
authors: Tamura
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002278:Carcinoma in Situ / Q000175:diagnosis* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed