title: Characterization of a CCD-based digital x-ray imaging system for small-animal studies: properties of spatial resolution.
abstract: A digital x-ray imaging system was designed for small-animal studies. This system is a fiber-optics taper-coupled imaging system with two CCD arrays uniquely jointed. The x-ray source of the system has a small focal spot of 20 microm. This digital imaging system contains specially designed shelves to provide magnification levels, ranging from 1.5x to 5x. The system is characterized in terms of its properties of spatial resolution. An observer-based spatial resolution measurement was conducted with a line-pair target and a sector test pattern. The modulation transfer function of the system, with different magnifications, was studied by use of a 10-microm lead slit. The average resolutions at 50% and 5% modulations at 1x magnification were measured as 3.9 and 8.4 lp/mm, respectively, where lp indicates line pairs. With 5x magnification, the 50% and the 5% modulations provided 13.2- and 29.9-lp/mm, respectively, average spatial resolutions. The measurements showed consistency between the two individual CCD arrays; the difference in resolution between the two CCDs is less than 1%, even at high magnifications.
authors: Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Norman 73109, USA.
authors: Fabrice
authors: F
authors: Ouandji
authors: Eric
authors: E
authors: Potter
authors: Wei R
authors: WR
authors: Chen
authors: Yuhua
authors: Y
authors: Li
authors: David
authors: D
authors: Tang
authors: Hong
authors: H
authors: Liu
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D005336:Fiber Optic Technology; D006801:Humans; D055100:Optical Fibers; D011856:Radiographic Image Enhancement / Q000295:instrumentation