title: Soft tissue uptake of Tc99m-MDP in acute lymphoblastic leukemia.
abstract: Acute lymphoblastic leukemia (ALL) is associated rarely with hypercalcemia. This may be due to elevated levels of parathyroid hormone-related peptide (PTHrP). We report a case of an 18-year-old female patient who was presented with a pathological fracture of left intertrochanteric region. Bone scintigraphy was consistent with features of hypercalcemia associated with metastatic calcification. A bone marrow biopsy led to the diagnosis of ALL. The mechanism of hypercalcemia in ALL, metastatic calcification and soft tissue uptake of bone seeking agents in this case are discussed in detail.
authors: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors: Atul
authors: A
authors: Marwah
authors: Rakesh
authors: R
authors: Kumar
authors: Bharathi
authors: B
authors: Dasan J
authors: Saikat
authors: S
authors: Choudhury
authors: Gurupad
authors: G
authors: Bandopadhyaya
authors: Arun
authors: A
authors: Malhotra
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000097:blood; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D014915:Whole-Body Counting
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate