Functional biosensor systems via surface-nanoengineering of electronic elements.
Bioelectronics is a progressing interdisciplinary research field that involves the integration of biomaterials with electronic transducers such as electrodes, field-effect transistors or piezoelectric crystals. Surface engineering of biomaterials such as enzymes, antigen-antibodies or DNA on the electronic supports controls the electrical properties of the biomaterial/transducer interface and enables the electronic transduction of biorecognition events, or biocatalyzed transformation, on the transducers. The development of biosensor systems of tailored sensitivities and specificities represents a major advance in bioelectronics.
Willner
Itamar
I
Institute of Chemistry, The Hebrew University of Jerusalem, Israel. willnea@vms.huji.ac.il
Willner
Bilha
B
Katz
Eugenii
E
D000937:Antigen-Antibody Reactions; D015374:Biosensing Techniques / Q000379:methods*; D004563:Electrochemistry; D004800:Enzymes, Immobilized; D036103:Nanotechnology / Q000379:methods*
D004800:Enzymes, Immobilized