title: The core structure of the lipopolysaccharide from the causative agent of plague, Yersinia pestis.
abstract: The rough-type lipopolysaccharide (LPS) of the plague pathogen, Yersinia pestis, was studied after mild-acid and strong-alkaline degradations by chemical analyses, NMR spectroscopy and electrospray-ionization mass spectrometry, and the following structure of the core region was determined:where L-alpha-D-Hep stands for L-glycero-alpha-D-manno-heptose, Sug1 for either 3-deoxy-alpha-D-manno-oct-2-ulosonic acid (alpha-Kdo) or D-glycero-alpha-D-talo-oct-2-ulosonic acid (alpha-Ko), and Sug2 for either beta-D-galactose or D-glycero-alpha-D-manno-heptose. A minority of the LPS molecules lacks GlcNAc.
authors: N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospekt 47,Moscow 119991, Russia.
authors: Evgeny V
authors: EV
authors: Vinogradov
authors: Buko
authors: B
authors: Lindner
authors: Nina A
authors: NA
authors: Kocharova
authors: Sof'ya N
authors: SN
authors: Senchenkova
authors: Aleksander S
authors: AS
authors: Shashkov
authors: Yuriy A
authors: YA
authors: Knirel
authors: Otto
authors: O
authors: Holst
authors: Tat'yana A
authors: TA
authors: Gremyakova
authors: Rima Z
authors: RZ
authors: Shaikhutdinova
authors: Andrei P
authors: AP
authors: Anisimov
mesh_terms: D002240:Carbohydrate Sequence; D008070:Lipopolysaccharides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009844:Oligosaccharides / Q000737:chemistry; D010930:Plague / Q000382:microbiology; D021241:Spectrometry, Mass, Electrospray Ionization; D015010:Yersinia pestis / Q000737:chemistry*
chemical_list: D008070:Lipopolysaccharides; D009844:Oligosaccharides