title: Beneficial therapeutic effects of physical training and relaxation therapy in women with coronary syndrome X.
abstract: OBJECTIVE
  New types of illness are being identified continuously. Owing to the demands for evidence-based practice, physiotherapeutic interventions need to be investigated scientifically prior to application in a new patient population. Coronary syndrome X (syndrome X) is a chronic pain disorder with exercise-induced chest pain despite angiographically normal coronary arteries. Patients with syndrome X constitute a therapeutic problem with considerable residual morbidity associated with functional limitation and reduced quality of life. Therefore, the aim of the present study was to investigate the effects of physical training and relaxation therapy on exercise capacity and quality of life in patients with syndrome X.
  
  
  METHODS
  A single-blind, randomized controlled trial design was used. Twenty-four female patients aged 41-65 years were randomly assigned to three groups: A, B and C. All groups were similar at baseline for physical fitness level. Group A performed physical training for eight weeks at 50% of baseline VO2max and group B participated in relaxation therapy for eight weeks. Group C acted as control subjects without any intervention. Before and after the eight-week periods, subjects were assessed by means of several measures of exercise capacity and quality of life.
  
  
  RESULTS
  The measured variables did not change in the control group during the eight weeks. VO2max (< 0.02), work rate (< 0.002) and distance walked during six minutes (< 0.003) increased only after physical training. The tolerated exertion during six minutes of walking (< 0.05) and the health-related quality of life, measured both by the Stress and Crisis Inventory (SCI) and the Sickness Impact Profile (SIP) (< 0.04), improved after both physical training and relaxation therapy. The general coping capacity, measured by the Sense of Coherence (SOC) questionnaire, remained unchanged in all the groups.
  
  
  CONCLUSIONS
  Female patients with syndrome X benefit from physical training in terms of exercise capacity and quality of life and from relaxation therapy in terms of quality of life.
authors: Department of Physical Therapy, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden. raija.tyni-lenne@physio.hs.sll.se
authors: Raija
authors: R
authors: Tyni-Lenne
authors: Signe
authors: S
authors: Stryjan
authors: Björn
authors: B
authors: Eriksson
authors: Margareta
authors: M
authors: Berglund
authors: Christer
authors: C
authors: Sylven
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D017566:Microvascular Angina / Q000534:rehabilitation*; D008875:Middle Aged; D011788:Quality of Life; D012064:Relaxation Therapy; D016037:Single-Blind Method