title: Diffusion tensor brain imaging and tractography.
abstract: Diffusion-tensor MR imaging is a promising tool to evaluate white-matter integrity by quantitative and graphic maps including neural fiber tractogram. Current challenges afoot are to obtain higher quality diffusion-weighted MR images (high SNR, isotropic voxel, and high spatial resolution), to create a robust mathematical framework to process the data, to construct a user-friendly computer-based algorithm, to reveal determinants of diffusion process, and to establish analytical methodology.
authors: Department of Radiology, Shiga University of Medical Science, Otsu, Shiga, Japan.
authors: Ryuta
authors: R
authors: Ito
authors: Susumu
authors: S
authors: Mori
authors: Elias R
authors: ER
authors: Melhem
mesh_terms: D000326:Adrenoleukodystrophy / Q000175:diagnosis / Q000473:pathology; D000818:Animals; D001812:Blood-Brain Barrier / Q000502:physiology*; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D002547:Cerebral Palsy / Q000175:diagnosis / Q000473:pathology; D004058:Diffusion; D016142:Holoprosencephaly / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D051379:Mice; D009412:Nerve Fibers / Q000473:pathology*; D009434:Neural Pathways / Q000473:pathology