Patch testing to exclude allergic contact dermatitis caused by povidone-iodine.
Povidone-iodine (polyvinylpyrrolidone-iodine, PVP-I) solution is an effective and safe disinfectant agent used throughout the world; however, prolonged exposure to PVP-I solution may cause irritation or rarely severe skin reactions. When PVP-I as is in the aqueous state is used for patch testing, a false-positive result is likely to arise due to irritation. Patch testing to exclude allergic contact dermatitis caused by PVP-I should be done with dried 10% PVP-I solution, 10% PVP-I gel, 8% sodium thiosulfuric acid and a mixture of 10% PVP-I solution and 8% sodium thiosulfuric acid.
Kozuka
Takehito
T
Department of Dermatology and Allergology, Osaka National Hospital, Osaka, Japan. kozukat@hch.2aq.ne.jp
D000368:Aged; D000891:Anti-Infective Agents, Local / Q000009:adverse effects* / Q000627:therapeutic use; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests / Q000379:methods; D011206:Povidone-Iodine / Q000009:adverse effects* / Q000627:therapeutic use
D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine