Acute myocardial infarction due to left main coronary artery occlusion. Therapeutic strategy.
OBJECTIVE
Acute myocardial infarction due to left main coronary artery occlusion remains catastrophic and mostly fatal due to severe cardiogenic shock and arrhythmia.


METHODS
We studied 13 patients undergoing coronary artery bypass grafting for acute myocardial infarction due to left main coronary artery occlusion to clarify the optimal management of these difficult patients.


RESULTS
In-hospital mortality was 46.2% (6/13). Revascularization was achieved by catheter intervention followed by bypass surgery in 7, and bypass surgery alone in 6. Two bypass surgery patients without catheter intervention had collateral flow to the left coronary artery, with the right coronary artery dominant. The time from onset to recanalization in the survival group was significantly shorter than in the early death group.


CONCLUSIONS
Emergency intervention to preserve left ventricular function or right coronary artery dominant and collateral blood flow to left coronary arteries is important for improving the prognosis of patients with acute myocardial infarction due to left main coronary artery occlusion. If residual left main coronary artery stenosis is significant or other proximal coronary stenosis exists after catheter intervention, early coronary bypass surgery may improve long-term survival.
Shigemitsu
Osamu
O
Department of Emergency Medicine, Oita Medical University, 1-1 Idaigaoka, Hasamamachi, Oita 879-5593, Japan.
Hadama
Tetsuo
T
Miyamoto
Shinji
S
Anai
Hirofumi
H
Sako
Hidenori
H
Iwata
Eriko
E
D000368:Aged; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000150:complications*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D012770:Shock, Cardiogenic / Q000209:etiology; D015996:Survival Rate