Current perspectives in the recognition and management of psoriatic arthritis: implications for integrated patient care.
Psoriatic arthritis (PsA), a chronic and debilitating spondyloarthropathy, is believed to affect as many as 30% of those with psoriasis. The use of tumor necrosis factor (TNF) inhibitors shows promise in the treatment of PsA and psoriasis. Etanercept, the first TNF inhibitor to be approved for use in PsA, inhibits the proinflammatory cytokine TNF in both conditions, making it possible for the clinician to prescribe a single agent to manage both the joint manifestations of PsA and the cutaneous manifestations of psoriasis. Etanercept has been shown to be well tolerated, even for long-term use, and is potentially superior to disease-modifying antirheumatic drugs.
Ruderman
Eric M
EM
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D015535:Arthritis, Psoriatic / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D019033:Delivery of Health Care, Integrated / Q000458:organization & administration*; D018450:Disease Progression; D006304:Health Status; D006801:Humans; D011379:Prognosis; D011788:Quality of Life; D014481:United States
D000893:Anti-Inflammatory Agents