Glucopyranosides derived from 6-aryl-5-cyano-2-(methylthio)pyrimidin-4(3H)ones.
The reaction of 2,3.4,6-tetra-O-acetyl-alpha-D-glucopyranosyl bromide with a 6-aryl-5-cyano-2-(methylthio)pyrimidin-4(3H)one in aqueous acetone in the presence of KOH furnishes a 4-(beta-D-glucopyranosyloxy)pyrimidine and a 3-(beta-D-glucopyranosyl)pyrimidine as the major and minor product. respectively.
Abdou
Ibrahim M
IM
Department of Chemistry, Georgia State University, Atlanta 30303, USA.
Attia
Adel M
AM
Strekowski
Lucjan
L
D005960:Glucosides / Q000138:chemical synthesis / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*
D005960:Glucosides; D011743:Pyrimidines