title: Amyloid-lowering isocoumarins are not direct inhibitors of gamma-secretase.
authors: William P
authors: WP
authors: Esler
authors: Chittaranjan
authors: C
authors: Das
authors: William A
authors: WA
authors: Campbell
authors: W Taylor
authors: WT
authors: Kimberly
authors: Anna Y
authors: AY
authors: Kornilova
authors: Thekla S
authors: TS
authors: Diehl
authors: Wenjuan
authors: W
authors: Ye
authors: Beth L
authors: BL
authors: Ostaszewski
authors: Weiming
authors: W
authors: Xia
authors: Dennis J
authors: DJ
authors: Selkoe
authors: Michael S
authors: MS
authors: Wolfe
mesh_terms: D053829:Amyloid Precursor Protein Secretases; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000235:genetics / Q000378:metabolism; D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000037:antagonists & inhibitors / Q000378:metabolism; D002460:Cell Line; D003374:Coumarins / Q000737:chemistry / Q000378:metabolism*; D010450:Endopeptidases / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000378:metabolism*; D006801:Humans
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D003374:Coumarins; D004791:Enzyme Inhibitors; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human