title: Prenatal diagnosis of partial agenesis of the corpus callosum in a fetus with thanatophoric dysplasia type 2.
abstract: A fetus with thanatophoric dysplasia type 2 (TD2) associated with cloverleaf skull and abnormal development of the corpus callosum is reported. This case represents the first prenatal direct visualization of a partial agenesis of the corpus callosum (ACC) using high-resolution ultrasonography and colour power Doppler, which was confirmed by post-mortem magnetic resonance imaging (MRI). The causal link between cloverleaf skull in TD and partial ACC is discussed.
authors: Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Medical Faculty of the Humboldt-University, Berlin, Germany. kkalache@med.wayne.edu
authors: Karim D
authors: KD
authors: Kalache
authors: Katarina
authors: K
authors: Lehmann
authors: Rabih
authors: R
authors: Chaoui
authors: Dietmar E
authors: DE
authors: Kivelitz
authors: Stefan
authors: S
authors: Mundlos
authors: Rainer
authors: R
authors: Bollmann
mesh_terms: D000025:Abortion, Eugenic; D000328:Adult; D061085:Agenesis of Corpus Callosum; D001927:Brain Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D011247:Pregnancy; D013796:Thanatophoric Dysplasia / Q000150:complications / Q000473:pathology*; D016216:Ultrasonography, Prenatal