Successful pregnancy and delivery after testicular sperm extraction despite an undetectable concentration of serum inhibin B in a patient with nonobstructive azoospermia.
OBJECTIVE
To describe a successful pregnancy and delivery after testicular sperm extraction (TESE) despite an undetectable concentration of serum inhibin B in a man with nonobstructive azoospermia.


METHODS
Case report.


METHODS
Obstetrics and gynecology and reproductive biology departments.


METHODS
A 31-year-old woman and a 32-year-old man with nonobstructive azoospermia and an undetectable inhibin B serum level.


METHODS
TESE, testicular spermatozoa cryopreservation, intracytoplasmic sperm injection (ICSI).


METHODS
Pregnancy and delivery.


RESULTS
Successful pregnancy and delivery of a normal healthy child following a third ICSI cycle with frozen-thawed spermatozoa extracted from the testis.


CONCLUSIONS
This case report shows that there is no minimal level of inhibin B below which TESE is always unsuccessful. The delivery of a normal healthy baby is strong evidence to perform TESE in these circumstances.
Guthauser
Bruno
B
Department of Reproductive Biology and Cytogenetics, Centre Hospitalier Poissy Saint Germain, Paris, France.
Bailly
Marc
M
Bergere
Marianne
M
Wainer
Robert
R
Ville
Yves
Y
Selva
Jacqueline
J
D000328:Adult; D015925:Cryopreservation; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007265:Inhibins / Q000097:blood*; D008297:Male; D009845:Oligospermia / Q000097:blood*; D011247:Pregnancy; D020554:Sperm Injections, Intracytoplasmic; D013094:Spermatozoa; D013737:Testis; D020858:Tissue and Organ Harvesting
C422364:inhibin B; D007265:Inhibins