Self-assembly of molecular capsules in polar solvents.
[structure: see text] We present a novel type of molecular capsule formed by self-organization of calix[4]arenes with several oppositely charged functional groups located at their upper rims. In highly polar solvents, the complementary half-spheres form stable 1:1 complexes with association constants of up to 7 x 10(5) M(-)(1) in methanol. The cavity inside the capsules is large enough for the inclusion of small aliphatic or (hetero)aromatic guest molecules.
Zadmard
Reza
R
Fachbereich Chemie, Universität Marburg, Hans-Meerwein-Strasse 35032, Germany.
Schrader
Thomas
T
Grawe
Thomas
T
Kraft
Arno
A
D047250:Calixarenes; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003198:Computer Simulation; D007202:Indicators and Reagents; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009010:Monte Carlo Method; D012997:Solvents; D021241:Spectrometry, Mass, Electrospray Ionization
D007202:Indicators and Reagents; D046911:Macromolecular Substances; D012997:Solvents; D047250:Calixarenes