title: Epithelioid hemangioendothelioma of the stomach: clinical-pathological features, nosologic setting, and surgical therapy. Report of a case.
abstract: Vascular tumors of the stomach represent 0.9%-3.3% of all gastric neoplasms. A 41-year-old man was admitted to our department with a 3-month history of early postprandial epigastric pain, sluggish digestion, nausea, asthenia, and occasional alimentary emesis. Preoperative staging detected a submucosal neoformation in the prepyloric zone, which narrowed the lumen, without any infiltrative features; a wedge gastric resection was performed and the definitive diagnosis was an epithelioid hemangioendothelioma of stomach. An 8-month follow up did not show any relapse of the disease. The term hemangioendothelioma is controversial because of disagreements regarding the nosologic setting and treatment. As a result, the latest WHO classification calls such neoplasms "borderline." The correct diagnosis depends on the histological findings supported by immunohistochemistry. Surgery represents the treatment of choice; however, a conservative approach is preferred whenever possible. However, due to the borderline biological behavior of this neoplasm, it is important that detailed clinical evaluations be carried out for such patients along with a thorough follow-up.
authors: Department of Human Pathology, University of Messina, Policlinico Universitario, Italy.
authors: Antonino
authors: A
authors: Versaci
authors: Antonio
authors: A
authors: Macri
authors: Giuseppe
authors: G
authors: Scuderi
authors: Grazia
authors: G
authors: Leonello
authors: Francesco
authors: F
authors: Fedele
authors: Antonio
authors: A
authors: Certo
authors: Marialuisa
authors: M
authors: Terranova
authors: Ciro
authors: C
authors: Famulari
mesh_terms: D000328:Adult; D018323:Hemangioendothelioma, Epithelioid / Q000145:classification / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D011706:Pyloric Antrum; D013274:Stomach Neoplasms / Q000145:classification / Q000473:pathology / Q000601:surgery*; D009626:Terminology as Topic