Performance characteristics of VIDAS and directigen respiratory syncytial virus (RSV) antigen detection assays and culture for the identification of RSV in respiratory specimens.
In a comparison of the Directigen and VIDAS respiratory syncytial virus antigen detection assays with viral culture, the sensitivity, specificity, positive and negative predictive values, and testing efficiency were 86, 93.1, 82.7, 94.6, and 91.2% for Directigen; 96.1, 90.8, 80.3, 98.3, and 92.3% for VIDAS; and 88.2, 100, 100, 95.7, and 96.8% for viral culture, respectively.
Ribes
Julie A
JA
Department of Pathology and Laboratory Medicine, MS-117 Medical Center, 800 Rose Street, University of Kentucky, Lexington, KY 40536-0293, USA. jaribes@uky.edu
Seabolt
John Pat
JP
Overman
Sue B
SB
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D002460:Cell Line; D006801:Humans; D008253:Macaca mulatta; D011237:Predictive Value of Tests; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis*; D012136:Respiratory Syncytial Viruses / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D014407:Tumor Cells, Cultured; D014773:Virology / Q000379:methods
D000956:Antigens, Viral