Myrsinoic acids B, C and F, anti-inflammatory compounds from Myrsine seguinii.
The methanolic extract of Myrsine seguinii yielded three anti-inflammatory compounds, myrsinoic acids B, C and F, and their structures were elucidated from the spectroscopic data. These compounds suppressed the TPA-induced edema of mouse ear, myrsinoic acid F being the most active (IE 77% at a dose of 0.56 micromol).
Hirota
Mitsuru
M
Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Kami-ina, Nagano, Japan. hirotam@gipmc.shinshu-u.ac.jp
Miyazaki
Shintaro
S
Minakuchi
Tomomi
T
Takagi
Tomoko
T
Shibata
Hisao
H
D000475:Alkenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D001572:Benzofurans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D002839:Chromans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D029623:Primulaceae / Q000737:chemistry*; D013055:Spectrophotometry, Infrared
D000475:Alkenes; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001572:Benzofurans; D002839:Chromans; D010936:Plant Extracts; C468150:myrsinoic acid B; C468151:myrsinoic acid C; C468152:myrsinoic acid F