title: Localized alveolar bone necrosis following the use of an arsenical paste: a case report.
abstract: OBJECTIVE
  To describe some toxic effects of arsenic trioxide in the mouth, to condemn its continued use, and present a case in which a tooth was preserved despite significant bony destruction.
  
  
  CONCLUSIONS
  A case is presented in which severe alveolar bone necrosis resulted from leak-age of an arsenical devitalization paste into the periodontium. The tooth was root canal treated before root amputation, and restored with a cuspal coverage restoration. The tooth was observed to be symptomless and functional at the one-year follow-up.
  
  
  CONCLUSIONS
  * Arsenic and its compounds have no place in contemporary endodontics. * Dentists should protect their patients by avoiding the use of arsenic-containing materials and refusing to use products whose constituents are not known. * Localized bone necrosis may not require tooth extraction. Depending on the severity of the case, the tooth may be preserved by a combination of endodontic, periodontal,prosthodontic and maintenance therapies.
authors: Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Turkey. nozmeric1@superonline.com
authors: N
authors: N
authors: Ozmeriç
mesh_terms: D000293:Adolescent; D000539:Alveolar Process / Q000187:drug effects* / Q000601:surgery; D020261:Arsenic Poisoning / Q000209:etiology*; D001152:Arsenicals / Q000009:adverse effects*; D003787:Dental Pulp Devitalization / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008336:Mandibular Diseases / Q000209:etiology / Q000601:surgery; D010020:Osteonecrosis / Q000209:etiology* / Q000601:surgery; D012390:Root Canal Therapy; D014092:Tooth Root / Q000601:surgery
chemical_list: D001152:Arsenicals