N-acetylcysteine in acute cardiology: 10 years later: what do we know and what would we like to know?!
N-acetylcysteine (NAC) is known in a variety of branches of medicine. This paper addresses in detail the action of NAC as it is emerging from research and clinical trials over the past decade in cardiology, giving rise to new concepts. The result is a process resembling creation of a mosaic from individual pieces. Also, the role of NAC in acute cardiology, during acute reperfusion in particular, is defined.
Sochman
Jan
J
Intensive care Unit, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.jan.sochman@medicon.cz
D000111:Acetylcysteine / Q000494:pharmacology* / Q000627:therapeutic use; D002309:Cardiology / Q000639:trends; D002986:Clinical Trials as Topic; D016166:Free Radical Scavengers / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy / Q000503:physiopathology; D015428:Myocardial Reperfusion Injury / Q000503:physiopathology* / Q000517:prevention & control; D018384:Oxidative Stress / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000378:metabolism; D016277:Ventricular Function, Left / Q000187:drug effects
D016166:Free Radical Scavengers; D017382:Reactive Oxygen Species; D000111:Acetylcysteine