title: Toxoplasma encephalitis in HIV: case report.
abstract: In Tanzania, no data are available on the prevalence of brain infection by toxoplasma in HIV-infected patients. A case of a 35-year old man with fulminant toxoplasma encephalitis (TE) is reported for the first time. TE was not suspected clinically in our patient who presented with a one week history of severe headache and treated empirically with antimalarial drugs. TE was diagnosed postmortem histologically by haematoxylin-eosin and immunohistochemical stain with P30 antibody for toxoplasma antigen. The findings in our case support the suggestion that a high index of suspicion for TE should be maintained in HIV-infected patients presenting with focal neurological symptoms. The case highlights the importance of autopsy studies in not only documenting a toxoplasma brain lesion but also in increasing the awareness for its diagnosis in HIV-infected patients in Tanzania and other developing countries.
authors: Department of Forensic Medicine, Kumamoto University School of Medicine, Japan.
authors: P M
authors: PM
authors: Ng'walali
authors: K
authors: K
authors: Kibayashi
authors: M P
authors: MP
authors: Mbonde
authors: A M
authors: AM
authors: Makata
authors: J N
authors: JN
authors: Kitinya
authors: S
authors: S
authors: Tsunenari
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000473:pathology*; D000328:Adult; D004660:Encephalitis / Q000150:complications / Q000473:pathology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008297:Male; D014123:Toxoplasmosis / Q000473:pathology*