[Standard designs of epidemiological studies and their characteristics in ophthalmology].
This text gives an overview on standard epidemiological study designs and their main advantages and limitations concerning clinical and economical aspects, of performance. Ophthalmological examples are used to illustrate the design characteristics of cross-sectional, cohort and case control studies. These designs are compared by the fictitious planning of an epidemiological study to assess the prophylactical relevance of intraocular antibiotics against post-cataract endophthalmitis; general practical hints for the designing of epidemiological studies are given.
Krummenauer
Frank
F
Koordinierungszentrum für Klinische Studien, Germany. krummi @imsd.uni-mainz.de
Kersten
Inga
I
D019072:Antibiotic Prophylaxis / Q000191:economics / Q000706:statistics & numerical data; D016022:Case-Control Studies; D002387:Cataract Extraction / Q000191:economics / Q000706:statistics & numerical data; D015331:Cohort Studies; D003362:Cost-Benefit Analysis; D003430:Cross-Sectional Studies; D009877:Endophthalmitis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D015340:Epidemiologic Research Design; D005128:Eye Diseases / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D005839:Gentamicins / Q000008:administration & dosage / Q000009:adverse effects; D005858:Germany; D006801:Humans; D008137:Longitudinal Studies; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control
D005839:Gentamicins