title: Signet-ring-cell carcinoma of the ampulla of Vater: a case report.
abstract: We encountered a rare variant of carcinoma of the ampulla of Vater in a 68-year-old man with postprandial abdominal pain and nausea. Ultrasonography and computed tomography showed a dilated common bile duct and main pancreatic duct. At duodenoscopy, the papilla of Vater was enlarged, and biopsy specimens taken from the papilla revealed signet-ring-cell carcinoma. Endoscopic ultrasonography showed a hypoechoic tumor without pancreatic invasion. Pylorus-preserving pancreatoduodenectomy was performed. Histologic examination of resected specimens indicated lymphatic and vascular invasion, but surgical margins were tumor-free. The patient is alive and disease-free 10 months after the operation.
authors: Department of Surgery, Kin-I-Kyo Chuou Hospital, 15-1, 10-jo, 2-chome, Fushiko, Higashi-ku, Sapporo, Hokkaido, 007-8505 Japan.
authors: Takashi
authors: T
authors: Hara
authors: Hideaki
authors: H
authors: Kawashima
authors: Masahiro
authors: M
authors: Ishigooka
authors: Motoya
authors: M
authors: Kashiyama
authors: Setsuji
authors: S
authors: Takanashi
authors: Yoshio
authors: Y
authors: Hosokawa
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000368:Aged; D014670:Ampulla of Vater; D018279:Carcinoma, Signet Ring Cell / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D003135:Common Bile Duct / Q000473:pathology; D003138:Common Bile Duct Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D010183:Pancreatic Ducts / Q000473:pathology; D016577:Pancreaticoduodenectomy