title: [Sepsis and septic shock: a turmoil of inflammatory mediators with difficult therapeutic management].
abstract: Sepsis and septic shock continue being a topic of enormous interest for their high frequency, and for not existing a decrease in the figures of mortality in spite of the new acquired knowledges relation with their physiopathology and the advances arisen in the diverse applied treatments. The purpose of the present study is to update the present notions in the specialized literature, trying to summarize the complex existent interaction among different mediators of double character: exogenous and endogenous, and to enunciate the possible causes for those that the novel treatments applied in the sepsis continue not to be very promising.
authors: Departamento de Cirugía, Facultad de Medicina, Universidad Complutense, Madrid.
authors: H J
authors: HJ
authors: Durán Giménez-Rico
authors: M A
authors: MA
authors: Aller Reyero
authors: L
authors: L
authors: Lorente Ruigómez
authors: L
authors: L
authors: Durán Giménez-Rico
authors: J
authors: J
authors: Arias Pérez
authors: H
authors: H
authors: Durán Sacristán
mesh_terms: D006801:Humans; D018836:Inflammation Mediators; D018805:Sepsis / Q000276:immunology* / Q000628:therapy; D012772:Shock, Septic / Q000276:immunology* / Q000628:therapy
chemical_list: D018836:Inflammation Mediators