title: Early versus late surgery for intractable seizures.
abstract: Certain drug-resistant epilepsies are highly responsive to surgery. Dr. Engel argues that there is no need to pursue exhaustive drug trials with these patients. If the first-line anticonvulsants fail, they should be referred directly to an epilepsy center and considered for surgical treatment.
authors: Department of Neurology, and Brain Research Institute, UCLA School of Medicine, Reed Neurological Research Center, Los Angeles, CA 90095-1769, USA.
authors: Jerome
authors: J
authors: Engel
mesh_terms: D004351:Drug Resistance; D006801:Humans; D019635:Neurosurgical Procedures; D012640:Seizures / Q000601:surgery*