[Disorder of lipid metabolism in visceral fat syndrome--relation to familial combined hyperlipidemia].
'Visceral fat syndrome' is a clinical entity compatible with Syndrome X, Deadly quartet, and insulin resistance syndrome. All of these entities express the pathophysiology of multiple risk factor syndrome in which multiple risks of arteriosclerosis, i.e., hypertension, hyperlipidemia, and glucose intolerance, cluster in an individual. The accumulation of visceral fat plays a crucial role in the pathogenesis of visceral fat syndrome. On the other hand, familial combined hyperlipidemia (FCHL) is a common hyperlipidemia associated with premature arteriosclerosis. The pathogenesis of FCHL is not fully elucidated but the visceral fat accumulation may play an important role in the pathophysiology of FCHL. In this review, we will discuss the relationship between visceral fat syndrome and FCHL.
Ishigami
Masato
M
Department of Internal Medicine and Molecular Science, Graduate School of Medicine.
Nakamura
Tadashi
T
Matsuzawa
Yuji
Y
D005260:Female; D006801:Humans; D006950:Hyperlipidemia, Familial Combined / Q000209:etiology* / Q000235:genetics; D015228:Hypertriglyceridemia / Q000150:complications*; D007333:Insulin Resistance; D008297:Male; D009765:Obesity / Q000150:complications*; D012307:Risk Factors