title: Occurrence of Neospora caninum antibodies in sera from dogs of the city of São Paulo, Brazil.
abstract: Neospora caninum is an important cause of abortion in dairy cattle worldwide. Dogs are important in the epidemiology of this parasite because they are the only hosts known to excrete N. caninum oocysts. In order to understand the prevalence of N. caninum in dogs, sera from 500 owned dogs and from over 600 feral street dogs from the city of São Paulo, Brazil were assayed for antibodies to N. caninum. Sera were examined by the Neospora agglutination test (NAT) using mouse-derived tachyzoites. Antibodies (> or =1:25) to N. caninum were found in nearly 10% (49/500) of owned dogs and in 25% (151/611) of stray dogs. NAT titers for owned dogs were 1:25 in 28 (5.6%) dogs, 1:50 in 20 (4%) dogs, and > or =1:500 in 1 (0.2%) dog. NAT titers for stray dogs were 1:25 in 79 (12.9%) dogs, 1:50 in 68 (11.1%) dogs, and > or =1:500 in 4 (0.6%) dogs. These data indicate that feral dogs may be important in the epidemiology of N. caninum infection.
authors.affiliation: Faculdade de Medicina Veterinária e Zootecnia, Departamento de Medicina Veterinária Preventiva e Saúde Animal, Universidade de São Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitária, SP 05508-000, São Paulo, Brazil. sgennari@usp.br
authors.forename: S M
authors.initials: SM
authors.lastname: Gennari
authors.forename: L E O
authors.initials: LE
authors.lastname: Yai
authors.forename: S N R
authors.initials: SN
authors.lastname: D'Auria
authors.forename: S M S
authors.initials: SM
authors.lastname: Cardoso
authors.forename: O C H
authors.initials: OC
authors.lastname: Kwok
authors.forename: M C
authors.initials: MC
authors.lastname: Jenkins
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
mesh_terms: D000372:Agglutination Tests / Q000662:veterinary; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D003048:Coccidiosis / Q000097:blood / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood / Q000453:epidemiology* / Q000469:parasitology; D004285:Dogs; D018688:Neospora / Q000276:immunology*; D015995:Prevalence; D016036:Seroepidemiologic Studies
chemical_list: D000913:Antibodies, Protozoan