In situ preparation of beta-D-1-O-hydroxylamino carbohydrate polymers mediated by galactose oxidase.
[reaction: see text] Galactose oxidase produced a C-6 aldehyde in various terminal-containing galactose hydroxylamines for the simultaneous in situ generation of an A-B type condensation for the construction of unique oxime polymers. Molecular weights of the corresponding polymers were determined to be in the range of 4200-8900 g/mol, respectively. This indicates that approximately 20-25 sugar units were incorporated in these unique polymers.
Andreana
Peter R
PR
Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489, USA.
Xie
Wenhua
W
Cheng
Huai N
HN
Qiao
Lei
L
Murphy
Dennis J
DJ
Gu
Qu-Ming
QM
Wang
Peng G
PG
D000447:Aldehydes / Q000138:chemical synthesis; D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D005692:Galactose Oxidase / Q000737:chemistry*; D006898:Hydroxylamines / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010091:Oximes / Q000138:chemical synthesis; D011108:Polymers / Q000138:chemical synthesis
D000447:Aldehydes; D006898:Hydroxylamines; D010091:Oximes; D011108:Polymers; D005692:Galactose Oxidase