title: [Neonatal endocarditis due to staphylococcus aureus as a complication of neonatal sepsis].
abstract: We present the case of a newborn with bacterial endocarditis with mitral valve involvement as a complication of late-onset sepsis due to Staphylococcus aureus with associated pyelonephritis and meningitis. The diagnosis was confirmed by echocardiogram and blood culture with growth of S. aureus. Treatment was medical and surgical. Neonatal bacterial endocarditis is extremely difficult to diagnose. The signs and symptoms are usually nonspecific and cannot be distinguished from those of sepsis or congenital heart disease. Consequently, a high degree of suspicion is needed for the early diagnosis of this condition. Echocardiography should be performed in children who present sepsis and heart murmur and even in those with staphylococcemia (sepsis due to S. aureus) without associated heart murmur. This investigation enables an early diagnosis of endocarditis to be made and appropriate treatment to be given without having to wait for the development of signs and symptoms that frequently go undetected.
authors.affiliation: Sección de Neonatología, Hospital del Mar, Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Esteban Torné
authors.forename: L
authors.initials: L
authors.lastname: Molina Ferragut
authors.forename: A
authors.initials: A
authors.lastname: Hernández Estaregui
authors.forename: O
authors.initials: O
authors.lastname: García-Algar
authors.forename: M
authors.initials: M
authors.lastname: Thió Lluch
authors.forename: J
authors.initials: J
authors.lastname: Moreno Hernando
authors.forename: A
authors.initials: A
authors.lastname: Mur Sierra
mesh_terms: D000328:Adult; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D006801:Humans; D008297:Male; D018805:Sepsis / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*