title: Low-pressure hydrocephalic state complicating hemispherectomy: a case report.
abstract: Low-pressure hydrocephalic state (LPHS) has only recently been described as a distinct clinical entity occurring in patients with bioatrophic lesions of the brain. We report a patient in whom this syndrome developed after subtotal hemispherectomy for intractable epilepsy.
  
  
  METHODS
  A 30-year-old man developed cerebrospinal fluid (CSF) rhinorrhea after subtotal hemispherectomy. After repair of the CSF dural fistula, clinical and radiological features of an LPHS developed. After external ventricular drainage for 26 days, a programmable low-pressure shunt system was instituted.
  
  
  RESULTS
  Worsening neurologic status and ventriculomegaly in the face of normal intraventricular pressures is diagnostic of this condition. The clinical status clearly correlated with ventricular size and not ventricular pressure.
  
  
  CONCLUSIONS
  LPHS is a clinically significant perioperative complication that rarely occurs after large brain excisions. Restoration of the baseline brain compliance is critical in the management of this condition.
authors.affiliation: Department of Neurosurgery, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia 5000. roymercy@hotmail.com
authors.forename: Roy Thomas
authors.initials: RT
authors.lastname: Daniel
authors.forename: Gabriel Y F
authors.initials: GY
authors.lastname: Lee
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Halcrow
mesh_terms: D000328:Adult; D001921:Brain / Q000601:surgery*; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D002557:Cerebrospinal Fluid Shunts; D004827:Epilepsy / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D007427:Intracranial Pressure / Q000502:physiology; D007431:Intraoperative Complications / Q000175:diagnosis / Q000453:epidemiology; D008279:Magnetic Resonance Imaging; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome