title: Granular cell tumor of the parotid gland. A case report.
abstract: BACKGROUND
  Granular cell tumor (GCT) is a relatively uncommon soft tissue tumor of putative Schwann cell origin. This tumor can occur in multiple sites as a small, nontender nodule, but the parotid gland is unusual, and only several cases have been reported.
  
  
  METHODS
  A 46-year-old woman presented with a slowly growing mass in the left preauricular region for three years. Imaging studies confirmed a nodular lesion in the superficial lobe of the left parotid gland. Fine needle aspiration (FNA) cytology revealed scattered cellular clusters and single cells with abundant granular cytoplasm and indistinct cell borders. Background exhibited eosinophilic, granular, cytoplasmic material, and some scattered naked nuclei were also noted. Histologic examination with supportive immunohistochemical and ultrastructural studies confirmed GCT.
  
  
  CONCLUSIONS
  GCT of the parotid gland is very unusual. Recognition of this tumor is important to make a definitive diagnosis before an operation. FNA is useful procedure in GCT of parotid gland for a preoperative diagnosis and proper treatment.
authors.affiliation: Department of Pathology, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, 94-200, Yeongdungpo-Dong, Yeongdeungpo-Ku, Seoul 150-020, Korea.
authors.forename: Seoung Wan
authors.initials: SW
authors.lastname: Chae
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: Sohn
authors.forename: Hyung Sik
authors.initials: HS
authors.lastname: Shin
mesh_terms: D018249:Adenoma, Oxyphilic / Q000175:diagnosis; D008949:Adenoma, Pleomorphic / Q000175:diagnosis; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D016586:Granular Cell Tumor / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D009418:S100 Proteins / Q000032:analysis / Q000276:immunology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D009418:S100 Proteins