Integrin adhesion: when is a kinase a kinase?
Recent genetic studies in the worm Caenorhabditis elegans and fruitfly Drosophila have revealed the essential role integrin-linked kinase plays in integrin adhesion - but it apparently acts in this role as an adaptor rather than a kinase.
Zervas
Christos G
CG
Department of Anatomy, University of Cambridge, Tennis Court Road, CB2 1QR, Cambridge, UK.
Brown
Nicholas H
NH
D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology* / Q000196:embryology / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D002448:Cell Adhesion; D004330:Drosophila / Q000201:enzymology / Q000378:metabolism; D022001:Focal Adhesions; D016023:Integrins / Q000378:metabolism*; D046911:Macromolecular Substances; D009132:Muscles / Q000166:cytology / Q000196:embryology / Q000201:enzymology / Q000378:metabolism; D011485:Protein Binding; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D000099200:Scaffold Protein ILK
D002352:Carrier Proteins; D016023:Integrins; D046911:Macromolecular Substances; D017346:Protein Serine-Threonine Kinases; D000099200:Scaffold Protein ILK