title: Lactic acid bacteria and proteomics: current knowledge and perspectives.
abstract: Lactic acid bacteria (LAB) are widely used in the agro-food industry. Some of the LAB also participate in the natural flora in humans and animals. We review here proteomic studies concerning LAB. Two methods of research can be distinguished. In the first one, a systematic mapping of proteins is attempted, which will be useful for taxonomy and to function assignment of proteins. The second one focuses particularly on proteins whose synthesis is induced by various environmental situations or stresses. However, both approaches are complementary and will give new insights for the use of bacteria in industry, in human health and in the struggle against bacterial pathogens. Interest in LAB is growing, showing thus an increasing concern of their rational use and one can foresee in the near future an increasing use of proteomics as well as genomics.
authors.affiliation: Unité Flore Lactique et Environnement Carné, INRA, 78352 Jouy-en-Josas Cedex, France.
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Champomier-Vergès
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Maguin
authors.forename: Michel-Yves
authors.initials: MY
authors.lastname: Mistou
authors.forename: Patricia
authors.initials: P
authors.lastname: Anglade
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Chich
mesh_terms: D001426:Bacterial Proteins / Q000302:isolation & purification / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D007778:Lactobacillus / Q000378:metabolism*; D009997:Osmotic Pressure; D020543:Proteome
chemical_list: D001426:Bacterial Proteins; D020543:Proteome