Cross-reaction of human chorionic gonadotrophin in Immulite 2000 luteinizing hormone assay.
METHODS
The cross-reactivity of human chorionic gonadotrophin (hCG) in the new DPC Immulite 2000 luteinizing hormone immunoassay was studied using sera from healthy pregnant women and pooled serum spiked with hCG standard IRP 75/537.


CONCLUSIONS
Significant positive bias was seen in sera from pregnant women and in IRP 75/537 spiked serum.
Vivekanandan
S
S
Department of Chemical Pathology, Barnet and Chase Farm Hospitals, Barnet, UK. svivek@barnet-chase-tr.nhs.uk
Andrew
Charles E
CE
D000568:Amenorrhea / Q000097:blood / Q000175:diagnosis; D000918:Antibody Specificity; D015982:Bias; D006063:Chorionic Gonadotropin / Q000097:blood* / Q000276:immunology*; D003429:Cross Reactions / Q000276:immunology*; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods* / Q000592:standards; D007986:Luteinizing Hormone / Q000097:blood* / Q000276:immunology*; D011247:Pregnancy; D011258:Pregnancy Tests / Q000379:methods / Q000592:standards; D011933:Reagent Kits, Diagnostic / Q000592:standards*
D006063:Chorionic Gonadotropin; D011933:Reagent Kits, Diagnostic; D007986:Luteinizing Hormone