Inflammatory bowel disease: dogmas and heresies.
Perception of a disease state by the practising physician is based on how easily the diagnosis can be made and how predictable the outcome of the chosen therapy is. The academic investigator perceives the same disease based on how well its cause and mechanism are understood, and how rational pathophysiology-based treatments are. Because of incomplete knowledge, neither the practising physician nor the academic investigator are comfortable in dealing with inflammatory bowel disease, and both seek help in the dogmas and heresies inevitably associated with chronic disease of unknown aetiology.
Fiocchi
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Division of Gastroenterology, University Hospitals of Cleveland, Case Western Reserve University School of Medicine, Ohio 44106-4952, USA. cxf18@po.cwru.edu
D000818:Animals; D003093:Colitis, Ulcerative / Q000235:genetics / Q000276:immunology / Q000503:physiopathology* / Q000628:therapy; D003424:Crohn Disease / Q000235:genetics / Q000276:immunology / Q000503:physiopathology* / Q000628:therapy; D006801:Humans