Will the real integrin please stand up?
Recent structure-function studies of integrins are beginning to unravel the mechanism of signal transduction across the plasma membrane, but controversy exists over the nature of the conformational changes underlying this process.
Liddington
Robert C
RC
Program on Cell Adhesion, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. rlidding@burnham.org
D016023:Integrins / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D015398:Signal Transduction / Q000502:physiology*; D013329:Structure-Activity Relationship
D016023:Integrins