title: Comparative study of permanganate oxidation reactions of nucleotide bases by spectroscopy.
abstract: The permanganate oxidation of free nucleotide bases was successfully studied in aqueous solution of tetraethylammonium chloride using spectroscopic techniques. The reaction was highly selective toward thymine and uracil, less with cytosine, very little reaction on guanine, and no reaction on adenine.
authors.affiliation: Genomic Disorders Research Centre, University of Melbourne, 7th Floor, Daly Wing, 41 Victoria Parade, Fitzroy, Melbourne, Victoria 3065, Australia. chinhbui@mail.medstv.unimelb.edu.au
authors.forename: Chinh T
authors.initials: CT
authors.lastname: Bui
authors.forename: Richard G H
authors.initials: RG
authors.lastname: Cotton
mesh_terms: D000225:Adenine / Q000737:chemistry / Q000378:metabolism; D003596:Cytosine / Q000737:chemistry / Q000378:metabolism; D006147:Guanine / Q000737:chemistry / Q000378:metabolism; D007700:Kinetics; D017895:Manganese Compounds / Q000737:chemistry / Q000378:metabolism*; D008722:Methods; D010084:Oxidation-Reduction / Q000187:drug effects; D010087:Oxides / Q000737:chemistry / Q000378:metabolism*; D011196:Potassium Permanganate / Q000737:chemistry / Q000378:metabolism; D011687:Purines / Q000737:chemistry / Q000378:metabolism*; D011743:Pyrimidines / Q000737:chemistry / Q000378:metabolism*; D013057:Spectrum Analysis; D013941:Thymine / Q000737:chemistry / Q000378:metabolism; D014498:Uracil / Q000737:chemistry / Q000378:metabolism
chemical_list: D017895:Manganese Compounds; D010087:Oxides; D011687:Purines; D011743:Pyrimidines; D011196:Potassium Permanganate; C048856:permanganic acid; D014498:Uracil; D006147:Guanine; D003596:Cytosine; D000225:Adenine; D013941:Thymine