Concentration-effect relationship for antimicrobial drugs.
The many relevant pharmacokinetic aspects influencing the relationship between antimicrobial drug concentration in the blood and at infection site with their pharmacodynamic effects are discussed, with particular regard to rules upon which clinical treatment modalities are based.
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Dipartimento di Farmacologia Preclinica e Clinica, Università degli Studi, Firenze, Italy.
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D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics* / Q000494:pharmacology*; D001424:Bacterial Infections / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D008962:Models, Theoretical
D000900:Anti-Bacterial Agents