title: Catabolite repression of Escherichia coli biofilm formation.
abstract: Biofilm formation was repressed by glucose in several species of Enterobacteriaceae. In Escherichia coli, this effect was mediated at least in part by cyclic AMP (cAMP)-cAMP receptor protein. A temporal role for cAMP in biofilm development was indicated by the finding that glucose addition after approximately 24 h failed to repress and generally activated biofilm formation.
authors.affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center at Fort Worth, Fort Worth, Texas 76107-2699, USA.
authors.forename: Debra W
authors.initials: DW
authors.lastname: Jackson
authors.forename: Jerry W
authors.initials: JW
authors.lastname: Simecka
authors.forename: Tony
authors.initials: T
authors.lastname: Romeo
mesh_terms: D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D000242:Cyclic AMP / Q000378:metabolism / Q000494:pharmacology*; D002373:Cyclic AMP Receptor Protein / Q000378:metabolism / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development*; D005947:Glucose / Q000378:metabolism; D006801:Humans
chemical_list: D002373:Cyclic AMP Receptor Protein; D000242:Cyclic AMP; D005947:Glucose