title: Increase in detrusor wall thickness indicates bladder outlet obstruction (BOO) in men.
abstract: Detrusor wall thickness decreases continuously while the bladder fills to 50% of its capacity and then remains constant until 100%. Therefore, detrusor wall measurements were performed in patients when the bladder was filled to maximum capacity only. Mean detrusor wall thickness for unobstructed (n = 14), equivocal (n=23) and obstructed patients (n=33) were 1.33, 1.62 and 2.4 mm, respectively (P <0.001). With increasing CHESS letters and CHESS numbers, the thickness of the detrusor wall increased as well (P< 0.001). The positive predictive value of detrusor wall measurement (95.5% for a cut-off value greater than or equal to 2 mm) was superior to all other predictors investigated. The thickness of the detrusor wall increases depending on the extent of BOO. Both constrictive and compressive BOO lead to an increase in detrusor wall thickness. BOO is found in 95.5% of men with a detrusor wall thickness greater than or equal to 2 mm. Measuring the thickness of the detrusor wall can be used as a screening test to detect BOO.
authors.affiliation: Department of Urology, Medical School Hannover, Germany. oelke.matthias@mh-hannover.de
authors.forename: Matthias
authors.initials: M
authors.lastname: Oelke
authors.forename: Klaus
authors.initials: K
authors.lastname: Höfner
authors.forename: Birgitt
authors.initials: B
authors.lastname: Wiese
authors.forename: Volker
authors.initials: V
authors.lastname: Grünewald
authors.forename: Udo
authors.initials: U
authors.lastname: Jonas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016022:Case-Control Studies; D003936:Diagnosis, Computer-Assisted; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011336:Probability; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D012016:Reference Values; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D001743:Urinary Bladder / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D001748:Urinary Bladder Neck Obstruction / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D014563:Urodynamics