Spectroscopic characterization of selected beta- sheet hairpin models.
The IR and vibrational circular dichroism (VCD) spectra of a model two-stranded beta hairpin are compared to those of a related cyclic two-stranded model, which are both stabilized by DPro- Gly turns. The spectra are compared to ab initio based simulations to support specific assignments of the dominant features and suggest a revised interpretation of the IR and VCD spectra for beta sheet containing proteins.
Hilario
Jovencio
J
Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, 60607- 7061, USA.
Kubelka
Jan
J
Syud
Faisal A
FA
Gellman
Samuel H
SH
Keiderling
Timothy A
TA
D002942:Circular Dichroism; D005799:Genes, Dominant; D010452:Peptide Biosynthesis; D010455:Peptides / Q000737:chemistry; D017433:Protein Structure, Secondary; D013055:Spectrophotometry, Infrared / Q000379:methods*; D017550:Spectroscopy, Fourier Transform Infrared
D010455:Peptides