title: Pulmonary vein gas analysis for assessing donor lung function.
abstract: BACKGROUND
  Radial artery oxygenation (PaO2) is the standard method for assessing potential lung donors. This study was proposed to assess the use of pulmonary vein gases (PvO2) in selection of donor lung for transplantation.
  
  
  METHODS
  We studied 170 lungs from 85 consecutive donors. Lungs were classified into group A, PaO2 and PvO2 > 300 mm Hg; group B, PaO2 < 300 mm Hg, and PvO2 > 300 mm Hg; and group C, PvO2 < 300 mm Hg.
  
  
  RESULTS
  Lungs retrieved from group A and group B were used for transplantation. Allograft function, assessed by the arterial and alveolar oxygen tension ratio, was similar at 12 hours and at 24 hours after operation (0.69, 0.73, vs 0.70, 0.71, for groups A and B, respectively (p = 0.8, 0.7, respectively). Similar radiologic appearance was seen in both groups (p = 0.2). Median duration of intubation was also similar (p = 0.6). The 30-day mortality rate was 12% versus 11.3% (p = 0.8), and 1-year survival rate was 80% versus 82% (p = 0.8) for recipient received lungs from group A and B donors, respectively.
  
  
  CONCLUSIONS
  Selective pulmonary veins analysis gives an accurate assessment of individual gas exchange in comparison with arterial PaO2, identifying more potential donor lungs for transplantation.
authors.affiliation: Transplant Unit, Wythenshawe Hospital, Manchester, United Kingdom. tarekaziz55@hotmail.com
authors.forename: Tarek M
authors.initials: TM
authors.lastname: Aziz
authors.forename: Ahmed
authors.initials: A
authors.lastname: El-Gamel
authors.forename: Rasheed A G
authors.initials: RA
authors.lastname: Saad
authors.forename: Marcello
authors.initials: M
authors.lastname: Migliore
authors.forename: Colin S
authors.initials: CS
authors.lastname: Campbell
authors.forename: Nizar A
authors.initials: NA
authors.lastname: Yonan
mesh_terms: D000328:Adult; D002423:Cause of Death; D005260:Female; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D016040:Lung Transplantation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis; D011659:Pulmonary Gas Exchange / Q000502:physiology; D011667:Pulmonary Veins; D015996:Survival Rate; D014019:Tissue Donors
chemical_list: D010100:Oxygen