Demodicidosis revisited.
Demodex mites are common commensals of the pilosebaceous unit in mammals. In humans, only two species (Demodex folliculorum and D. brevis) have been identified and have been implied to play a role in at least three facial conditions: pityriasis folliculorum, rosacea-like demodicidosis and so-called "demodicidosis gravis". However, there is no consensus to what degree the mites are causative of the skin pathology and how they might contribute to the disease. This review presents a demodicidosis case, discusses the clinical features of Demodex infestation in man and reviews its pathogenetic implications and the therapeutic options.
Baima
B
B
Department of Dermatology, University of Leipzig, Germany. baib@vz.uni-leipzig.de
Sticherling
M
M
D000328:Adult; D017677:Age Distribution; D000818:Animals; D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000469:parasitology / Q000473:pathology; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage; D008924:Mite Infestations / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D008925:Mites / Q000145:classification*; D011379:Prognosis; D012307:Risk Factors; D012393:Rosacea / Q000175:diagnosis; D017678:Sex Distribution; D016896:Treatment Outcome
D008795:Metronidazole