Embryo transfer on day 3 using low versus high fluid volume.
OBJECTIVE
To assess the success of in vitro fertilization when embryos were transferred with low or high fluid volume.


METHODS
A total of 191 consecutive embryo transfer cycles were performed with low (15-20 microl, n=94) or with high (40-50 microl, n=97) fluid volume at an University-based IVF center. In a retrospective analysis, differences in the pregnancy rate were compared by the two-tailed t-test.


RESULTS
There was no significant difference with regard to patients' age, number of previous attempts, number of oocytes recovered and fertilization rate. Compared to low fluid volume, a high volume for loading the transfer catheter resulted in significantly higher pregnancy (40% versus 23%, P=0.012) and implantation rate (24.4% versus 14.7%, P=0.011).


CONCLUSIONS
For transfer of embryos on day 3 the amount of fluid volume for transfer has a significant impact on pregnancy and implantation rates.
Montag
Markus
M
Department of Endocrinology and Reproductive Medicine, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany. m.montag@uni-bonn.de
Kupka
Markus
M
van der Ven
Katrin
K
van der Ven
Hans
H
D000328:Adult; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies; D012996:Solutions; D020554:Sperm Injections, Intracytoplasmic; D013997:Time Factors
D012996:Solutions