title: A case of cutaneous delayed-type allergy to oral dexamethasone and to betamethasone.
abstract: Corticosteroids are drugs that may cause allergic contact dermatitis, but systemic allergic reactions to these drugs are rare. A 29-year-old man developed a maculopapular rash during an oral therapy with betamethasone. Patch tests demonstrated a delayed-type allergy to dexamethasone, betamethasone and fluocortolone. Oral, intramuscular or topical provocation tests with other corticosteroids - deflazacort, hydrocortisone, methylprednisolone, fluticasone dipropionate, triamcinolone and prednisone - were all negative. This demonstrates that a patient with a systemic allergy to a group of corticosteroids can tolerate those of other groups.
authors.affiliation: Department of Allergology, Policlinico 'A. Gemelli', Università Cattolica del Sacro Cuore, Roma, Italia.
authors.forename: Eleonora
authors.initials: E
authors.lastname: Nucera
authors.forename: Alessandro
authors.initials: A
authors.lastname: Buonomo
authors.forename: Emanuela
authors.initials: E
authors.lastname: Pollastrini
authors.forename: Tiziana
authors.initials: T
authors.lastname: De Pasquale
authors.forename: Massimiliona
authors.initials: M
authors.lastname: Del Ninno
authors.forename: Chiara
authors.initials: C
authors.lastname: Roncallo
authors.forename: Domenico
authors.initials: D
authors.lastname: Schiavino
authors.forename: Giampiero
authors.initials: G
authors.lastname: Patriarca
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects; D001623:Betamethasone / Q000008:administration & dosage / Q000009:adverse effects*; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D004342:Drug Hypersensitivity; D005500:Follow-Up Studies; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced*; D008297:Male; D010035:Otitis Media, Suppurative / Q000188:drug therapy; D010328:Patch Tests; D018570:Risk Assessment
chemical_list: D000893:Anti-Inflammatory Agents; D003907:Dexamethasone; D001623:Betamethasone