The role of Th1/Th2 polarization in mucosal immunity.
Mucosal immunity relies on the delicate balance between antigen responsiveness and tolerance. The polarization of T helper cells plays a key role in maintaining or disrupting this equilibrium.
Neurath
Markus F
MF
Laboratory of Immunology, I. Department of Medicine, University of Mainz, Mainz, Germany. neurath@1-med-klinik.uni-mainz.de
Finotto
Susetta
S
Glimcher
Laurie H
LH
D000818:Animals; D001249:Asthma / Q000276:immunology; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D016764:Cell Polarity; D006801:Humans; D018928:Immunity, Mucosal / Q000502:physiology*; D015212:Inflammatory Bowel Diseases / Q000276:immunology; D018448:Models, Immunological; D018417:Th1 Cells / Q000276:immunology / Q000502:physiology*; D018418:Th2 Cells / Q000276:immunology / Q000502:physiology*