title: Anesthetic considerations in the patient with a heart transplant.
abstract: As programs to increase the awareness of organ donation grow, more patients undergo cardiac transplantation. Because immunosuppressive therapy and postoperative care are improved, the 1-year survival rate of these patients has increased to more than 80%. Not surprisingly, these patients may, either coincidentally or as a result of medications, require other procedures using anesthesia, frequently at hospitals other than the highly specialized institution that performed the transplant. Because the denervated heart responds differently than the normal heart to many perioperative drugs, physicians, including cardiologists who are frequently consulted preoperatively, must have a special awareness of the particular problems in this group of patients.
authors.affiliation: Department of Anesthesiology, Texas Tech University Medical Center, Lubbock, TX 79430, USA.
authors.forename: Nishan
authors.initials: N
authors.lastname: Ashary
authors.forename: Alan D
authors.initials: AD
authors.lastname: Kaye
authors.forename: Amr R
authors.initials: AR
authors.lastname: Hegazi
authors.forename: Elizabeth A M
authors.initials: EA
authors.lastname: M  Frost
mesh_terms: D000758:Anesthesia / Q000009:adverse effects / Q000379:methods; D000777:Anesthetics / Q000009:adverse effects* / Q000627:therapeutic use; D004347:Drug Interactions; D005260:Female; D006084:Graft Rejection; D006085:Graft Survival; D006333:Heart Failure / Q000401:mortality / Q000601:surgery; D016027:Heart Transplantation / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D019990:Perioperative Care; D011379:Prognosis; D018570:Risk Assessment; D016019:Survival Analysis; D014181:Transplantation Immunology
chemical_list: D000777:Anesthetics; D007166:Immunosuppressive Agents