Circumcision in a combined factor V and factor VIII deficiency using desmopressin (DDAVP).
Combined factor V and VIII deficiency is a rare inherited autosomal recessive single gene disorder commonly seen in the Middle East. Although the factor levels are between 5-30%, several authors have reported that these patients are more prone to bleeding compared to those having an isolated factor deficiency with the same levels. We report an eight-year-old boy with factor V and VIII deficiency who underwent a successful circumcision using desmopressin (DDAVP).
Devecioğlu
Omer
O
Department of Pediatrics, Istanbul Faculty of Medicine, Istanbul University, Turkey.
Eryilmaz
Ertuğrul
E
Celik
Dicle
D
Unüvar
Ayşegül
A
Karakaş
Zeynep
Z
Anak
Sema
S
Ağaoğlu
Leyla
L
D002648:Child; D002944:Circumcision, Male / Q000009:adverse effects*; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D005166:Factor V Deficiency / Q000150:complications*; D006467:Hemophilia A / Q000150:complications*; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D037241:Mannose-Binding Lectins; D008565:Membrane Proteins / Q000235:genetics
D006490:Hemostatics; C084004:LMAN1 protein, human; D037241:Mannose-Binding Lectins; D008565:Membrane Proteins; D003894:Deamino Arginine Vasopressin