title: Is meconium passage a risk factor for maternal infection in term pregnancies?
abstract: OBJECTIVE
  To study the association between meconium and maternal infection.
  
  
  METHODS
  This was a retrospective cohort study of 678 pregnant women. All term deliveries during a 31-month period with meconium passage were included. Each meconium delivery was matched with a consecutive delivery without meconium at the same gestational age.
  
  
  RESULTS
  The overall infection rate was 16%, with 13% of the infections directly related to the pregnancy, labor, and delivery. The endometritis rate was 5%, with 7.1% and 3% in the meconium and no-meconium group, respectively. The chorioamnionitis rate was 8.3%, with 9.5% in the meconium and 7.1% in the no-meconium group. Factors found to be associated with overall obstetric infections had the following odds ratios (ORs) and 95% confidence intervals (CIs): meconium (OR 1.8, 95% CI 1.1, 2.8), internal monitoring (OR 3.4, 95% CI 1.9, 5.9), amnioinfusion (OR 2.0, 95% CI 1.3, 3.3), number of vaginal exams (OR 4.5, 95% CI 2.8, 7.1), length of labor (OR 2.8, 95% CI 1.8, 4.4), and cesarean (OR 3.1, 95% CI 1.9, 5.1). Logistic regression analyses revealed the following ORs and 95% CIs: 1) for endometritis-cesarean (OR 4.2, 95% CI 1.9, 8.9), internal monitoring (OR 2.5, 95% CI 1.1, 5.9), and meconium (OR 2.5, 95% CI 1.1, 5.5), and 2) for chorioamnionitis-length of labor greater than 10 hours (OR 2.7, 95% CI 1.4, 5.6), number of vaginal exams greater than seven (OR 3.4, 95% CI 1.7, 6.6), and use of internal monitors (OR 2.5, 95% CI 1.2, 5.3).
  
  
  CONCLUSIONS
  Meconium passage increases the risk of postpartum endometritis but not chorioamnionitis. Length of labor, internal monitoring, and number of vaginal exams are risk factors for chorioamnionitis.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. allahyar.jazayeri@ttmc.ttuhsc.edu
authors.forename: Allahyar
authors.initials: A
authors.lastname: Jazayeri
authors.forename: Mary K
authors.initials: MK
authors.lastname: Jazayeri
authors.forename: Michelle
authors.initials: M
authors.lastname: Sahinler
authors.forename: Terry
authors.initials: T
authors.lastname: Sincich
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002821:Chorioamnionitis / Q000453:epidemiology*; D015331:Cohort Studies; D004716:Endometritis / Q000453:epidemiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007743:Labor, Obstetric; D016015:Logistic Models; D008413:Mastitis / Q000453:epidemiology; D008470:Meconium; D007744:Obstetric Labor Complications / Q000453:epidemiology*; D010033:Otitis Media / Q000453:epidemiology; D011247:Pregnancy; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000453:epidemiology