The prevalence of high-grade prostatic intraepithelial neoplasia in surgical resection specimens: an Indian experience.
BACKGROUND
To the authors' knowledge there is a paucity of literature regarding the prevalence of high-grade prostatic intraepithelial neoplasia (HGPIN) in the Indian subcontinent. The objective of the current study was to document the prevalence of HGPIN in a low-risk Indian population.


METHODS
SA total of 110 prostate specimens (61 taken from the test group and 49 taken from the control group) were studied to document the prevalence of HGPIN in a low-risk Indian population.


RESULTS
None of the benign prostate samples were found to harbor HGPIN, whereas 85.24% of the samples from malignant prostates did so.


CONCLUSIONS
SA strong correlation between HGPIN and invasive carcinoma was observed, a finding that reinforces the view that HGPIN is a strong indicator of concurrent invasive prostate carcinoma.
Desai
Sangeeta B
SB
Department of Pathology, Tata Memorial Hospital, Mumbai, India. sangeetabdesai@rediffmail.com
Borges
Anita M
AM
D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D019048:Prostatic Intraepithelial Neoplasia / Q000453:epidemiology*; D011471:Prostatic Neoplasms / Q000453:epidemiology*