title: Vitamin D(3): synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D(3) analogues.
abstract: The synthesis and biological activities of seco C-9,11,21-trisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) analogues (D-ring analogues) are described.
authors.affiliation: Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan 281 S4, B-9000 Gent, Belgium.
authors.forename: Yusheng
authors.initials: Y
authors.lastname: Wu
authors.forename: Katrien
authors.initials: K
authors.lastname: Sabbe
authors.forename: Pierre
authors.initials: P
authors.lastname: De Clercq
authors.forename: Maurits
authors.initials: M
authors.lastname: Vandewalle
authors.forename: Roger
authors.initials: R
authors.lastname: Bouillon
authors.forename: Annemieke
authors.initials: A
authors.lastname: Verstuyf
mesh_terms: D000818:Animals; D002460:Cell Line; D002762:Cholecalciferol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D018167:Receptors, Calcitriol / Q000187:drug effects; D013552:Swine
chemical_list: C468811:C-9,11,21-trisnor-17-methyl-1, 25-dihydroxyvitamin D3; D018167:Receptors, Calcitriol; D002762:Cholecalciferol