D-psicose is a rare sugar that provides no energy to growing rats.
D-Psicose (D-ribo-2-hexulose), a C-3 epimer of D-fructose, is present in small quantities in commercial carbohydrate complexes and agricultural products. We have previously reported that D-psicose supplements in diets suppressed hepatic lipogenic enzyme activity The lower fat accumulation in rats fed D-psicose may be due to lower lipogenesis in the liver. The present study examined the energy available in D-psicose for rat growth. Male Wistar rats received 7 g daily of a basal diet to which fixed amounts of sucrose, D-fructose, or D-psicose (0.5-2.0 g) were added for 20 d. Body weight gain and body energy gain increased with increases in sucrose and D-fructose, but not with D-psicose. One gram of sucrose, D-fructose, and D-psicose produced a net energy gain of 2.29, 1.76, and 0.007 kcal, respectively. The efficiency of energy deposition from D-psicose was 0.3% that of sucrose. The energy value of D-psicose was effectively zero. These results suggest that D-psicose is a rare sugar providing zero energy that may be useful in sweeteners for obese people as an aid for weight reduction.
Matsuo
Tatsuhiro
T
Faculty of Agriculture, Kagawa University, Japan. matsuo@ag.kagawa-u.ac.jp
Suzuki
Hiroo
H
Hashiguchi
Mineo
M
Izumori
Ken
K
D000818:Animals; D001823:Body Composition / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D002432:Cecum / Q000378:metabolism; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D019587:Dietary Supplements; D002149:Energy Intake / Q000502:physiology*; D005243:Feces; D005632:Fructose / Q000008:administration & dosage*; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013395:Sucrose / Q000008:administration & dosage; D013997:Time Factors
D004040:Dietary Carbohydrates; C003243:psicose; D005632:Fructose; D013395:Sucrose; D009584:Nitrogen