title: Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848.
authors.forename: Marion
authors.initials: M
authors.lastname: Jurk
authors.forename: Florian
authors.initials: F
authors.lastname: Heil
authors.forename: Jörg
authors.initials: J
authors.lastname: Vollmer
authors.forename: Christian
authors.initials: C
authors.lastname: Schetter
authors.forename: Arthur M
authors.initials: AM
authors.lastname: Krieg
authors.forename: Hermann
authors.initials: H
authors.lastname: Wagner
authors.forename: Grayson
authors.initials: G
authors.lastname: Lipford
authors.forename: Stefan
authors.initials: S
authors.lastname: Bauer
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002460:Cell Line; D029721:Drosophila Proteins; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology*; D008562:Membrane Glycoproteins / Q000187:drug effects / Q000235:genetics / Q000276:immunology*; D051379:Mice; D016328:NF-kappa B / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000235:genetics / Q000276:immunology*; D051199:Toll-Like Receptor 7; D051200:Toll-Like Receptor 8; D051193:Toll-Like Receptors; D014162:Transfection
chemical_list: D000276:Adjuvants, Immunologic; D000998:Antiviral Agents; D029721:Drosophila Proteins; D007093:Imidazoles; D008562:Membrane Glycoproteins; D016328:NF-kappa B; D011956:Receptors, Cell Surface; C495348:TLR7 protein, human; C495349:TLR8 protein, human; D051199:Toll-Like Receptor 7; D051200:Toll-Like Receptor 8; D051193:Toll-Like Receptors; C402365:resiquimod