Immunomodulatory effect of tungstate on streptozotocin-induced experimental diabetes in rats.
Immune dysfunction has been found to be associated with diabetes mellitus. Tungstate treatment restored the number and function of immune cells as well as the immunoglobulin level in STZ diabetic rats. This indicated the immunomodulatory effect of tungstate in diabetics and would be effective in inhibiting diabetic-induced alterations.
Palanivel
R
R
Department of Medical Biochemistry, Dr. ALM Postgraduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai 600 113, India.
Sakthisekaran
D
D
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000188:drug therapy* / Q000276:immunology*; D007107:Immune System / Q000166:cytology / Q000187:drug effects*; D007136:Immunoglobulins / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013311:Streptozocin / Q000494:pharmacology; D017973:Tungsten Compounds / Q000494:pharmacology* / Q000627:therapeutic use*
D007136:Immunoglobulins; D017973:Tungsten Compounds; D013311:Streptozocin; C045951:tungstate