title: [Noninvasive cardiac diagnosis for quantifying scarring, ischemia and pump function within the scope of a study. 20 useful facets in routine cardiology nuclear medicine practice].
abstract: Myocardial perfusion SPECT (MPS) commonly is interpreted qualitatively and not quantitatively. Most of the prognostic literature is based on a semi-quantitative visual analysis (SQA) of MPS. However, data about the comparison between the SQA and coronary angiography (cath) is lacking. We therefore evaluated 167 patients who underwent MPS and subsequent cath. SQA using a 20 segment model was used for MPS interpretation. Patients with a small to moderate amount of ischemia (SDS < or = 4; mean 1.2 +/- 1.5) and with extensive ischemia (SDS > 4; mean 9.6 +/- 4.7) were then compared with respect to clinical and cath variables. Patients with extensive ischemia had more advanced CAD as demonstrated by several cath variables (more often triple vessel and LAD-disease). SQA therefore is a useful tool for MPS interpretation and decision making in patients with (suspected) CAD.
authors.affiliation: Abteilung für Kardiologie und Institut für Nuklearmedizin, Universitätskliniken, Kantonsspital Basel.
authors.forename: M J
authors.initials: MJ
authors.lastname: Zellweger
authors.forename: M
authors.initials: M
authors.lastname: Gutmann
authors.forename: J
authors.initials: J
authors.lastname: Müller-Brand
authors.forename: M E
authors.initials: ME
authors.lastname: Pfisterer
mesh_terms: D000368:Aged; D002921:Cicatrix / Q000000981:diagnostic imaging*; D017023:Coronary Angiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*; D011379:Prognosis; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*