title: Multienzyme complexes of eukaryotic aminoacyl-tRNA synthetases.
abstract: Eukaryotic aminoacyl-tRNA synthetases, unlike their prokaryotic counterparts, may occur as high-Mr multienzyme complexes. Recently, successful purification of synthetase complexes makes possible the elucidation of the structural organization of these high-Mr complexes. Although their physiological significance remains unknown, recent studies suggest some possible functional roles for these complexes.
authors.affiliation: Department of Biochemistry, School of Medicine, Loma Linda University, California 92350, USA.
authors.forename: C V
authors.initials: CV
authors.lastname: Dang
authors.forename: C V
authors.initials: CV
authors.lastname: Dang
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D000604:Amino Acyl-tRNA Synthetases / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D000818:Animals; D004789:Enzyme Activation; D004795:Enzyme Stability; D005057:Eukaryotic Cells / Q000201:enzymology*; D008970:Molecular Weight; D009097:Multienzyme Complexes / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D010944:Plants; D020836:Protein Structure, Quaternary
chemical_list: D000596:Amino Acids; D009097:Multienzyme Complexes; D000604:Amino Acyl-tRNA Synthetases