title: Management of long-term failure after colon interposition for benign disease.
abstract: OBJECTIVE
  To assess causes and treatment of late failures of colon interposition.
  
  
  METHODS
  We reviewed the charts of 6 patients who underwent one or more revisions of a colonic interposition at a mean of 16 years after colon interposition (CI).
  
  
  RESULTS
  Symptoms of problems with the CI were dysphagia (67%), regurgitation (67%), pneumonia (40%), and chest pain (33%). Findings that accounted for failure were colonic redundancy (67%), and gastrocolonic reflux (50%). Approach was resection of redundant colon or management of reflux. Four patients underwent segmental resection of the colon preserving blood supply. Three patients had gastric resection or diversion of bile and acid for management of reflux. Treatment was successful in all patients.
  
  
  CONCLUSIONS
  Late failure of colon interposition is secondary to conduit redundancy and severe reflux. Resection of redundant colon will correct colonic redundancy. Gastric resection or diversion of bile and acid corrects gastrocolonic reflux.
authors.affiliation: Department of Surgery, Oregon Health Sciences University, Portland, OR 97201, USA.
authors.forename: John S
authors.initials: JS
authors.lastname: Domreis
authors.forename: Blair A
authors.initials: BA
authors.lastname: Jobe
authors.forename: Ralph W
authors.initials: RW
authors.lastname: Aye
authors.forename: Karen E
authors.initials: KE
authors.lastname: Deveney
authors.forename: Brett C
authors.initials: BC
authors.lastname: Sheppard
authors.forename: Clifford W
authors.initials: CW
authors.lastname: Deveney
mesh_terms: D003106:Colon / Q000637:transplantation*; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D004935:Esophageal Diseases / Q000601:surgery*; D016629:Esophagectomy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012086:Reoperation; D013997:Time Factors; D017211:Treatment Failure