title: Biochemistry. DNA building block reinvented.
authors.affiliation: MRC Centre for Protein Engineering, Hills Road, Cambridge CB2 2QH, UK. agm@mrc-lmb.cam.ac.uk
authors.forename: Alexey G
authors.initials: AG
authors.lastname: Murzin
mesh_terms: D001419:Bacteria / Q000201:enzymology; D001665:Binding Sites; D018360:Crystallography, X-Ray; D003856:Deoxyuracil Nucleotides / Q000378:metabolism; D015195:Drug Design; D004791:Enzyme Inhibitors; D019143:Evolution, Molecular; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D016480:Helicobacter pylori / Q000201:enzymology*; D006801:Humans; D008780:Methyltransferases / Q000737:chemistry / Q000378:metabolism; D008958:Models, Molecular; D010802:Phylogeny; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D015800:Protozoan Proteins / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D013763:Tetrahydrofolates / Q000378:metabolism; D020124:Thermotoga maritima / Q000201:enzymology*; D013938:Thymidine Monophosphate / Q000096:biosynthesis*; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*
chemical_list: D003856:Deoxyuracil Nucleotides; D004791:Enzyme Inhibitors; D015800:Protozoan Proteins; D013763:Tetrahydrofolates; D005182:Flavin-Adenine Dinucleotide; D013938:Thymidine Monophosphate; C030371:5,6,7,8-tetrahydrofolic acid; C007267:2'-deoxyuridylic acid; D008780:Methyltransferases; C024841:ribothymidyl synthase; D013940:Thymidylate Synthase