Diastereocontrolled synthesis of trans- and cis-meso-cyclopentene aziridines.
[reaction: see text] The synthesis of novel substituted meso-aziridines is described: aziridination of 4-tert-butyldiphenylsilyloxy-cyclopent-1-ene is trans selective using Cu(I)/PhI=NSO(2)Ar and cis selective using PhNMe(3)(+)Br(3)(-)/Chloramine-T.
Caine
Darren
D
Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
O'Brien
Peter
P
Rosser
Clare M
CM