title: Tachycardia and convulsions induced by accidental intravascular ropivacaine injection during sciatic block.
abstract: Ropivacaine, a recently introduced local anesthetic of the amide family (1), seems to show less toxicity than bupivacaine (2-4). Nevertheless, both neurologic and cardiovascular toxicities are possible. Six cases of ropivacaine-induced convulsions have previously been reported (5-10), of which three cases also showed cardiovascular toxicity. In three cases, total plasma concentrations were measured (Table 1).
authors.affiliation: Department of Anesthesia and Intensive Care, Begin Military Hospital, Saint Mande, France. cpetitjeans@wanadoo.fr
authors.forename: F
authors.initials: F
authors.lastname: Petitjeans
authors.forename: G
authors.initials: G
authors.lastname: Mion
authors.forename: M
authors.initials: M
authors.lastname: Puidupin
authors.forename: J P
authors.initials: JP
authors.lastname: Tourtier
authors.forename: C
authors.initials: C
authors.lastname: Hutson
authors.forename: J M
authors.initials: JM
authors.lastname: Saissy
mesh_terms: D000328:Adult; D000577:Amides / Q000009:adverse effects* / Q000097:blood; D000779:Anesthetics, Local / Q000009:adverse effects* / Q000097:blood; D006801:Humans; D008297:Male; D009407:Nerve Block / Q000009:adverse effects*; D000077212:Ropivacaine; D012584:Sciatic Nerve; D012640:Seizures / Q000139:chemically induced*; D013610:Tachycardia / Q000139:chemically induced*
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine