title: ACE inhibitors vs ARBs: is one class better for heart failure.
abstract: Although angiotensin-converting enzyme (ACE) inhibitors decrease mortality in heart failure, they incompletely suppress angiotensin II with long-term therapy. Since angiotensin receptor blockers (ARBs) block the biologic effects of angiotensin II more completely than ACE inhibitors, they could be beneficial in the treatment of heart failure.
authors.affiliation: Case Western Reserve University School of Medicine, and Louis B. Stokes Cleveland VA Medical Center, Cleveland, OH 44106, USA. med3@po.cwru.edu
authors.forename: Mark E
authors.initials: ME
authors.lastname: Dunlap
authors.forename: Ross C
authors.initials: RC
authors.lastname: Peterson
mesh_terms: D000368:Aged; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D018450:Disease Progression; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D012084:Renin-Angiotensin System / Q000502:physiology; D016896:Treatment Outcome
chemical_list: D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors