title: A case of NK/T-cell lymphoma complicated by a squamous cell carcinoma of hard palate during combination chemotherapy and radiation therapy.
abstract: NK/T-cell lymphoma, which often shows an angiocentric growth pattern, is a distinct clinicopathologic entity highly associated with Epstein-Barr virus. The disease is characterized by a destruction of the upper respiratory tract, particularly the nasal cavity, palate and paranasal sinuses. Interestingly, NK/T-cell lymphoma is closely linked to a variety of complications, such as hemophagocytic syndrome, second primary cancer, sepsis and bleeding. Here we report a case of a 50-year-old man diagnosed initially as NK/T-cell lymphoma of the oropharynx and who developed a second primary carcinoma of the hard palate during combination chemotherapy and radiation therapy.
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Hang Lak
authors.initials: HL
authors.lastname: Lee
authors.forename: Myung Ju
authors.initials: MJ
authors.lastname: Ahn
authors.forename: Jung Hye
authors.initials: JH
authors.lastname: Choi
authors.forename: Woon Hyun
authors.initials: WH
authors.lastname: Jun
authors.forename: Young Yuel
authors.initials: YY
authors.lastname: Lee
authors.forename: In Soon
authors.initials: IS
authors.lastname: Kim
authors.forename: Il Young
authors.initials: IY
authors.lastname: Choi
authors.forename: Se Jin
authors.initials: SJ
authors.lastname: Jang
authors.forename: Yong Wook
authors.initials: YW
authors.lastname: Park
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D006801:Humans; D007694:Killer Cells, Natural; D016399:Lymphoma, T-Cell / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000628:therapy; D009959:Oropharyngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D010157:Palatal Neoplasms / Q000473:pathology* / Q000628:therapy