[Studies on the chemical constituents of Smilax glabra].
Smilax glabra is a well-known traditional Chinese medicine which has been used clinically to prevent leptospirosis, to treat syphilis, and acute bacterial dysentery, etc. Its extracts showed anti-tumor and anti-atherosclerosis activity. A new isoflavone, 7,6'-dihydroxy 3'-methoxy isoflavone (1), along with two known compounds taxifolin (2) and astilbin (3), have been isolated from the roots of Smilax glabra. The structures were elucidated by spectroscopic methods including 2DNMR techniques.
Yi
Y
Y
Jiangsu Province Institute of Materia Medica, China Pharmaceutical University, Nanjing 210009.
Cao
Z
Z
Yang
D
D
Cao
Y
Y
Wu
Y
Y
Zhao
S
S
D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D044948:Flavonols; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification*; D019668:Liliaceae / Q000737:chemistry; D015394:Molecular Structure; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D032281:Smilax / Q000737:chemistry*
C470255:7,6'-dihydroxy-3'-methoxyisoflavone; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D044948:Flavonols; D007529:Isoflavones; C099069:astilbin; D011794:Quercetin; C003377:taxifolin