title: [Evaluation of the functional state of endotheliocytes of microcirculatory vessels from white rats].
abstract: Using ultrastructural computer tomography, 3-dimensional models of nucleoli of nucleolonemal, intermediate and circular types as well as of their Ag-NOR-protein distribution were developed for the endotheliocytes of the blood vessels of microcirculatory bed in white rats. It was demonstrated that the maturation process was associated with a decline in fibrillar center numbers, in dense fibrillar component and in other nucleolar subcomponents, while their spatial interrelationships were found to undergo significant changes. Dynamics of reorganization of Ag-NOR-protein distribution in these nucleoli also indicates the substantial reduction of transcription.
authors.affiliation: Department of Experimental Anatomy, Institute of Experimental Morphology of Georgian Academy of Sciences, Tbilisi, Georgia.
authors.forename: Iu R
authors.initials: IuR
authors.lastname: Arveladze
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000166:cytology* / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000166:cytology* / Q000648:ultrastructure; D005069:Evaluation Studies as Topic; D008833:Microcirculation; D008854:Microscopy, Electron; D051381:Rats