Fungal infections: correlation with previous treatment and use of antimycogram.
From July 1987 to November 1988, 427 strains of mycetes (2.3% out of all microbiological samples) were isolated; 280 of these strains (146 from 84 in-patients, 134 from out-patients) were clinically relevant, and the cause of serious or systemic infections in 47 in-patients. Candida sp. (albicans and non-albicans) were the most frequently isolated (62% in-patients, 72% out-patients): Torulopsis sp., more frequent among in-patients (28% against 16%), were responsible for a limited hospital epidemic. 108 antimycograms were done; 7 patients had antimycotic treatment. In our hands antimycograms were useful in tracing hospital fungal infections. Before mycoses were detected, 78% of in-patients were on antibiotic treatment: 54 on 3rd generation cephalosporins, which seem to foster the outburst of fungi. The authors discuss the phenomenon and suggest some interpretation.
Grandis
C
C
Divisione di Medicina Generale, Ospedale degli Infermi, Rivoli (TO), Italy.
Balagna
M E
ME
Malandrino
M
M
Marocco
A
A
D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000302:isolation & purification / Q000472:pathogenicity; D002177:Candidiasis / Q000188:drug therapy / Q000453:epidemiology; D003428:Cross Infection; D006801:Humans; D009181:Mycoses / Q000188:drug therapy* / Q000453:epidemiology; D012189:Retrospective Studies
D000935:Antifungal Agents