title: Pericardiectomy for constrictive pericarditis: is prolonged inotropic support a bad omen?
abstract: Sixty-seven patients who underwent pericardiectomy for constrictive pericarditis at JIPMER, Pondicherry between 1987 and 1998 were the subjects of the study. Pre-operatively 70% of cases were in the New York Heart Association classes III and IV categories with clinical signs suggestive of constriction ie, raised jugular venous pressure in 99%, pleural effusion in 77%, pedal oedema in 61% and ascites in 55% of the cases. Seventy-five per cent of the cases underwent pericardiectomy through a median sternotomy and the rest via left anterolateral thoracotomy. Low cardiac output was evidenced in 70% of cases postoperatively which was managed by early institution and prolonged use of inotropes. There was 9% mortality especially in the early part of the experience. Tuberculous pathology was confirmed histologically in 57% cases. Sixty-three per cent of cases are presenting in follow-up in New York Heart Association class I. Prolonged use of inotropes instituted early in postoperative period is recommended to prevent postoperative ventricular dysfunction with adrenaline being the preferred inotrope. It is concluded that postoperative New York Heart Association class and long term survival were not significantly influenced by pre-operative New York Heart Association class, operative approach or peri-operative low cardiac output syndrome requiring prolonged inotropic support.
authors.affiliation: Department of Cardiothoracic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.
authors.forename: A
authors.initials: A
authors.lastname: Kohli
authors.forename: K S
authors.initials: KS
authors.lastname: Rao
authors.forename: M
authors.initials: M
authors.lastname: Nachiappan
authors.forename: M A
authors.initials: MA
authors.lastname: Geelani
authors.forename: J
authors.initials: J
authors.lastname: Balachander
authors.forename: A
authors.initials: A
authors.lastname: Bannerjee
authors.forename: T K
authors.initials: TK
authors.lastname: Jayakumar
authors.forename: P
authors.initials: P
authors.lastname: Alam
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D010492:Pericardiectomy / Q000009:adverse effects*; D010494:Pericarditis, Constrictive / Q000601:surgery; D018754:Ventricular Dysfunction / Q000209:etiology* / Q000517:prevention & control*
chemical_list: D002316:Cardiotonic Agents