Oxygen saturation measurement of calf muscle during exercise in intermittent claudication.
OBJECTIVE
to evaluate the oxygen saturation of the calf muscle measured by means of spatially resolved spectroscopy (SRS) in claudicants.


METHODS
a total of 150 legs in 84 consecutive patients with calf claudication were studied by SRS. Oxygen saturation (SmO(2)) and the relative changes in oxygenated haemoglobin (HbO(2)) and deoxygenated haemoglobin (Hb) of the gastrocnemius muscle were measured during a treadmill walking test (2.4 km/h, 12%, 5 min).


RESULTS
exercise was associated with a decrease in HbO(2) and an increase in Hb. There was no difference in SmO(2) at rest among all groups. The decrease oxygen saturation correlated well with the severity of symptoms of IC.


CONCLUSIONS
muscle oxygen saturation measurement by SRS can be used clinically to provide objective information regarding the severity of IC.
Komiyama
T
T
Division of Vascular Surgery, Department of Surgery, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan.
Onozuka
A
A
Miyata
T
T
Shigematsu
H
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007383:Intermittent Claudication / Q000097:blood* / Q000503:physiopathology*; D007866:Leg / Q000098:blood supply* / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000502:physiology; D010100:Oxygen / Q000097:blood*; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013057:Spectrum Analysis; D013997:Time Factors
D006454:Hemoglobins; D010100:Oxygen