title: [Severe thyroid ophthalmopathy related to interferon alpha therapy].
abstract: The authors report a case of a 49-year-old patient presenting with dysthyroid ophthalmopathy, who was treated with interferon alpha for chronic hepatitis C. Proptosis appeared 3 months after treatment onset and many complications occurred over more than 1 year. The extreme severity seen in this case is infrequent. After a summary of other ocular damage linked to interferon, the authors suggest that every interferon treatment include a check-up before beginning therapy and regular biological and ophthalmological monitoring.
authors.affiliation: Service d'Ophtalmologie, Hospital Henri Mondor, Cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Binaghi
authors.forename: C
authors.initials: C
authors.lastname: Lévy
authors.forename: C
authors.initials: C
authors.lastname: Douvin
authors.forename: M
authors.initials: M
authors.lastname: Guittard
authors.forename: G
authors.initials: G
authors.lastname: Soubrane
authors.forename: G
authors.initials: G
authors.lastname: Coscas
mesh_terms: D005260:Female; D006111:Graves Disease / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D016898:Interferon-alpha