title: [Double-pump implantation chemotherapy for hepatic metastasis from colorectal cancer].
abstract: OBJECTIVE
  To evaluate the value of infusion chemotherapy by pump implantation via hepatic artery or portal vein or both (double-pump chemotherapy, DPC) for hepatic metastasis from colorectal cancer.
  
  
  METHODS
  Thirty patients with hepatic metastasis from colorectal cancer were divided into three groups: 1. Group I-DPC (12 patients). 2. Group II-hepatic artery implantation chemotherapy (10 patients) and 3. Group III-portal vein implantation chemotherapy (8 patients).
  
  
  RESULTS
  Response rate was 66.7% in group I, 60% in group II and 37.5% in group III. The 0.5-, 1-, 2-year survival rates were 100.0%, 75.0%, 41.7% in group I, 90.0%, 60.0%, 30.0% in group II and 87.5%, 50.0%, 25.0% in group III.
  
  
  CONCLUSIONS
  Double pump implantation chemotherapy is effective in treating hepatic metastasis from colorectal cancer. It is better than hepatic artery or portal vein pump-implantation chemotherapy alone.
authors.affiliation: 309th Hospital, PLA, Beijing 100091, China.
authors.forename: Jianmiao
authors.initials: J
authors.lastname: He
authors.forename: Yongdong
authors.initials: Y
authors.lastname: Pu
authors.forename: Zhidong
authors.initials: Z
authors.lastname: Zhu
authors.forename: Zhiyu
authors.initials: Z
authors.lastname: Cao
authors.forename: Bo
authors.initials: B
authors.lastname: Yang
authors.forename: Liguo
authors.initials: L
authors.lastname: Dong
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004358:Drug Therapy / Q000379:methods; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D007262:Infusions, Intravenous; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D013812:Therapeutics