title: Cytokinesis: regulated by destruction.
abstract: Important transitions in the cell cycle are regulated by ubiquitin-dependent degradation of specific proteins. Recent data indicate that cytokinesis is also regulated by proteolysis.
authors.affiliation: Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030, Vienna, Austria. mglotzer@nt.imp.univie.ac.at
authors.forename: Michael
authors.initials: M
authors.lastname: Glotzer
authors.forename: Reinhard
authors.initials: R
authors.lastname: Dechant
mesh_terms: D064173:Anaphase-Promoting Complex-Cyclosome; D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D002455:Cell Division; D020090:Chromosome Segregation; D004625:Embryo, Nonmammalian / Q000166:cytology* / Q000378:metabolism*; D008025:Ligases / Q000378:metabolism; D008938:Mitosis; D012617:Sea Urchins / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D008941:Spindle Apparatus / Q000378:metabolism; D025801:Ubiquitin / Q000378:metabolism*; D043743:Ubiquitin-Protein Ligase Complexes
chemical_list: D025801:Ubiquitin; D043743:Ubiquitin-Protein Ligase Complexes; D064173:Anaphase-Promoting Complex-Cyclosome; D008025:Ligases