title: Mapping the SRY gene in Microtus cabrerae: a vole species with multiple SRY copies in males and females.
abstract: The SRY gene is a single-copy, male-specific gene, located on the Y chromosome in most mammals. However, recently we have described the presence of multiple polymorphic copies of this gene in both males and females of the vole species Microtus cabrerae. Here, we present the chromosomal localization of SRY gene copies in this species by fluorescent in situ hybridization (FISH). This technique localized these gene copies in the short arm, and hence in the euchromatic region, of the Y chromosome. Furthermore, several copies of the SRY gene are located on the X chromosome. These copies are spread along the entire heterochromatic region of the X chromosome, occupying the whole short arm, the centromeric region, and the pericentromeric region of the long arm.
authors.affiliation: Departamento de Psicobiología, Facultad Ciencias de la Educación, Universidad de A Coruña, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Fernández
authors.forename: María José L
authors.initials: MJ
authors.lastname: Barragán
authors.forename: Mónica
authors.initials: M
authors.lastname: Bullejos
authors.forename: Juan Alberto
authors.initials: JA
authors.lastname: Marchal
authors.forename: Sergio
authors.initials: S
authors.lastname: Martínez
authors.forename: Rafael
authors.initials: R
authors.lastname: Díaz de la Guardia
authors.forename: Antonio
authors.initials: A
authors.lastname: Sánchez
mesh_terms: D000818:Animals; D003411:Arvicolinae / Q000235:genetics*; D005260:Female; D018628:Gene Dosage; D024282:Genes, sry; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D014960:X Chromosome; D014998:Y Chromosome