title: Disseminated strongyloidiasis in nephrotic syndrome.
abstract: Strongyloides stercoralis is endemic in the southwestern islands Amami and Ryukyu in Japan. Systemic strongyloidiasis occurs in immunocompromised hosts. We report here on a 60-year-old patient with minimal-change nephrotic syndrome (MCNS) without eosinophilia or HTLV-I infection. She was treated with corticosteroid for MCNS and died of disseminated strongyloidiasis. The patient developed systemic purpura, ileus, respiratory distress, malabsorption, pancytopenia, pulmonary hemorrhage and sepsis due to Escherichia coli before death. Massive infestation with Strongyloides stercoralis was disclosed by autopsy, and the larvae was considered as a pathomechanism or exacerbating agent of nephrotic syndrome in endemic areas.
authors.affiliation: Kidney Center, Fukuoka University Hospital, Second Department of Pathology, School of Medicine, Fukuoka University, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Morimoto
authors.forename: H
authors.initials: H
authors.lastname: Kaneoka
authors.forename: Y
authors.initials: Y
authors.lastname: Sasatomi
authors.forename: Y Nakai
authors.initials: YN
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Murata
authors.forename: S
authors.initials: S
authors.lastname: Ogahara
authors.forename: N
authors.initials: N
authors.lastname: Sakata
authors.forename: S
authors.initials: S
authors.lastname: Takebayashi
authors.forename: S
authors.initials: S
authors.lastname: Naito
authors.forename: T
authors.initials: T
authors.lastname: Saito
mesh_terms: D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000473:pathology; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D011507:Proteinuria / Q000209:etiology; D013322:Strongyloidiasis / Q000150:complications* / Q000175:diagnosis
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone