[Monthly cycles of 1-week therapy with itraconazole for patients with Tinea pedis].
Monthly cycles of 1-week therapy with oral itraconazole at 200 mg daily for tinea pedis was assessed to determine its acceptability to patients. Thirty-four patients (17 men and 17 women) with intractable tinea pedis, with informed consent, took 200 mg of itraconazole once daily for one week over a month period until mycological studies showed negative results for up to 4 months. The overall mycological effectiveness was about 80% after this therapy. Information was also gathered on the influence of this therapy on the patients quality of life by questionnaires. Nineteen (70%) among the 27 patients who answered the questionnaire preferred this 1-week administration of itraconazole over a month-long period compared with continuous daily therapy. Twenty-two (81%) preferred this therapy over topical treatment. We recommend to this therapy be added for the treatment of intractable tinea pedis.
Kobayashi
Hiromi
H
Department of Dermatology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
Mizuno
Nobuyuki
N
Nakanishi
Takeshi
T
Fukai
Kazuyoshi
K
Ishii
Masamitsu
M
Morimoto
Kensuke
K
D000284:Administration, Oral; D000935:Antifungal Agents / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D020551:Pulse Therapy, Drug; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014008:Tinea Pedis / Q000188:drug therapy*
D000935:Antifungal Agents; D017964:Itraconazole