Vitamin D(3): synthesis of seco-C-9,11-bisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) analogues.
The synthesis and biological properties of seco-C-9,11-bisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) novel D-ring analogues are described.
Wu
Yusheng
Y
Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan 281 S4, B-9000 Gent, Belgium.
De Clercq
Pierre
P
Vandewalle
Maurits
M
Bouillon
Roger
R
Verstuyf
Annemieke
A
D000818:Animals; D002762:Cholecalciferol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D051379:Mice; D018167:Receptors, Calcitriol / Q000187:drug effects; D013552:Swine
C468812:C-9,11-bisnor-17-methyl-1, 25-dihydroxyvitamin D3; D018167:Receptors, Calcitriol; D002762:Cholecalciferol