Improved sample extraction and clean-up for the GC-MS determination of BADGE and BFDGE in vegetable oil.
A straightforward method was established for the determination of migration contaminants in olive oil with a special focus on the two can-coating migration compounds bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE). The preferred sample preparation was a single liquid-liquid extraction of compounds from the oil into 20% (v/v) methanol in acetonitrile, followed by clean-up with solid-phase extraction on aminopropyl bonded to silica. This purification procedure selectively removed all free fatty acids from the extracts without removing phenolic compounds of interest. The solid-phase extraction columns were used many times by implementing a procedure of washing out the strongly retained fatty acids with 2% acetic acid in methanol. Gas chromatography coupled with full scan (m/z 33-700) electron ionization mass spectrometry was used for the determination of several model compounds in olive oil samples. BADGE and BFDGE could be determined in the 0.05-2 mg kg(-1) range in oil samples with a relative SD of <6% (six replicates). The method was used in an enforcement campaign for the Norwegian Food Control Authority to analyse vegetable oil samples from canned fish-in-oil.
Brede
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C
Naeringsmiddeltilsynet for Midt-Rogaland, Forusbeen 3, N-4033 Stavanger, Norway. cato.brede@nmt-mrog.rl.no
Skjevrak
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I
Herikstad
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H
Anensen
E
E
Austvoll
R
R
Hemmingsen
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T
D000818:Animals; D001559:Benzhydryl Compounds; D002273:Carcinogens / Q000032:analysis*; D004852:Epoxy Compounds / Q000032:analysis*; D005399:Fishes; D005506:Food Contamination / Q000032:analysis*; D018857:Food Packaging; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D010938:Plant Oils / Q000737:chemistry*; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D002273:Carcinogens; D004852:Epoxy Compounds; D010938:Plant Oils; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds; C423722:bisphenol F diglycidyl ether