title: Five new iboga alkaloids from Tabernaemontana corymbosa.
abstract: Five new indole alkaloids of the ibogan type (1-5), in addition to 12 other known iboga alkaloids, were obtained from the leaf and stem-bark extract of the Malayan species Tabernaemontana corymbosa, viz., 19(S)-hydroxyibogamine (1), 19-epi-isovoacristine (2), isovoacryptine (3), 3R/S-ethoxyheyneanine (4), and 3R/S-ethoxy-19-epi-heyneanine (5). The structures were determined using NMR and MS analysis and comparison with known related compounds.
authors.affiliation: Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia. tskam@kimia.um.edu.my
authors.forename: Toh-Seok
authors.initials: TS
authors.lastname: Kam
authors.forename: Kooi-Mow
authors.initials: KM
authors.lastname: Sim
mesh_terms: D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D008296:Malaysia; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013237:Stereoisomerism; D030014:Tabernaemontana / Q000737:chemistry*
chemical_list: D026121:Indole Alkaloids