Granular cell tumor of the parotid gland. A case report.
BACKGROUND
Granular cell tumor (GCT) is a relatively uncommon soft tissue tumor of putative Schwann cell origin. This tumor can occur in multiple sites as a small, nontender nodule, but the parotid gland is unusual, and only several cases have been reported.


METHODS
A 46-year-old woman presented with a slowly growing mass in the left preauricular region for three years. Imaging studies confirmed a nodular lesion in the superficial lobe of the left parotid gland. Fine needle aspiration (FNA) cytology revealed scattered cellular clusters and single cells with abundant granular cytoplasm and indistinct cell borders. Background exhibited eosinophilic, granular, cytoplasmic material, and some scattered naked nuclei were also noted. Histologic examination with supportive immunohistochemical and ultrastructural studies confirmed GCT.


CONCLUSIONS
GCT of the parotid gland is very unusual. Recognition of this tumor is important to make a definitive diagnosis before an operation. FNA is useful procedure in GCT of parotid gland for a preoperative diagnosis and proper treatment.
Chae
Seoung Wan
SW
Department of Pathology, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, 94-200, Yeongdungpo-Dong, Yeongdeungpo-Ku, Seoul 150-020, Korea.
Sohn
Jin Hee
JH
Shin
Hyung Sik
HS
D018249:Adenoma, Oxyphilic / Q000175:diagnosis; D008949:Adenoma, Pleomorphic / Q000175:diagnosis; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D016586:Granular Cell Tumor / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology* / Q000648:ultrastructure; D009418:S100 Proteins / Q000032:analysis / Q000276:immunology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D009418:S100 Proteins