Persistent polyclonal B-cell lymphocytosis.
We present a case of persistent polyclonal B-cell lymphocytosis (PPBL). This syndrome is characterized by a persistent lymphocytosis with circulating atypical binucleated lymphocytes. The patient had serological evidence of a previous EBV infection, had raised polyclonal serum IgM levels and was a heavy smoker. No malignancy was detected.
Ide
L
L
Department of Haematology, Laboratory Medicine, University Hospital Gasthuisberg, Leuven, Belgium. Nancy.Boeckx@uz.kuleuven.ac.be
Dekoninck
A
A
Verburgh
E
E
Goossens
W
W
Brusselmans
C
C
Boeckx
N
N
Emonds
M P
MP
Vandekerckhove
P
P
D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology*; D020031:Epstein-Barr Virus Infections; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008218:Lymphocytosis / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D012907:Smoking
D007075:Immunoglobulin M