title: [Influence of hydrocortisone on Schistosoma mansoni development in Biomphalaria glabrata].
abstract: The effect of hydrocortisone on the development of BH strain of S. mansoni in B. glabrata snails is evaluated. Snails in a randomly chosen group were submitted to hydrocortisone during four days. In the second day of hydrocortisone exposure, the snails were exposed, each, to ten S. mansoni miracidia. Another group, not treated with hydrocortisone, was exposed to miracidia and observed in the same manner. Various items of data were observed: the infection rate, survival time, prepatent period and total number of cercariae released. It was found that the snails in the group treated with hydrocortisone had a higher infection rate, shorter prepatent periods, produced more cercariae and also had longer survival times. This suggests that the hydrocortisone in snails induces a decrease in resistance to schistosome infection and facilitates the development of the trematode, while also reducing adverse infection effects, thereby leading to longer snail survival.
authors.affiliation: Departamento de Parasitologia, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, SP, Brasil.
authors.forename: Deborah Regina
authors.initials: DR
authors.lastname: Serrano
authors.forename: Eliana Maria
authors.initials: EM
authors.lastname: Zanotti-Magalhaes
authors.forename: Luiz Augusto
authors.initials: LA
authors.lastname: Magalhaes
authors.forename: José Ferreira de
authors.initials: JF
authors.lastname: Carvalho
mesh_terms: D000818:Animals; D001700:Biomphalaria / Q000469:parasitology*; D006854:Hydrocortisone / Q000494:pharmacology*; D021261:Parasitic Sensitivity Tests; D012550:Schistosoma mansoni / Q000187:drug effects* / Q000254:growth & development*
chemical_list: D006854:Hydrocortisone