Stage I vitamin D-deficiency rickets mimicking pseudohypoparathyroidism type II.
The clinical presentation and biochemical features of stage I vitamin D-deficiency rickets (VDR) and pseudohypoparathyroidism (PHP) type II are quite similar. These 2 entities have therefore often been mistaken for one another. We report our experience with 2 cases of stage I VDR that were originally diagnosed as PHP type II. The report provides an insight into the pathophysiology of VDR and PHP and thus allows for better differentiation between the 2 disease entities. It has become essential for pediatricians to recognize VDR owing to its resurgence in developed countries.
Srivastava
Tarak
T
Section of Nephrology and Bone and Mineral Disorders Clinic, The Children's Mercy Hospital, University of Missouri at Kansas City 64108, USA.
Alon
Uri S
US
D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D008297:Male; D010281:Parathyroid Hormone / Q000502:physiology; D011547:Pseudohypoparathyroidism / Q000175:diagnosis* / Q000503:physiopathology; D012279:Rickets / Q000175:diagnosis* / Q000503:physiopathology
D010281:Parathyroid Hormone