Effect of Semecarpus anacardium nuts on lipid peroxidation.
Alcoholic extract of pericarp showed significant protection against FeSO4 induced lipid peroxidation, as compared with whole native nut and seeds. Mechanism of action may be through metal chelation or activation of endogenous antioxidant enzymes, because the extract did not show hydroxyl and super oxide anion scavenging property. Further in vitro experiments against FeSO4, it did not maintain the level of reduced glutathione.
Tripathi
Y B
YB
Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. yamini@banaras.ernet.in
Singh
A V
AV
D027926:Anacardiaceae / Q000196:embryology*; D000818:Animals; D005296:Ferrous Compounds / Q000494:pharmacology; D015227:Lipid Peroxidation / Q000187:drug effects; D051379:Mice; D012639:Seeds
D005296:Ferrous Compounds; C020748:ferrous sulfate