title: Glycosidation of alkylamino-alkan-1-ol. A simple and convenient synthesis of glycosylated cationic lipids.
abstract: Starting from long chain alkylamino-alkan-1-ol a series of amino glycolipids were synthesized. This procedure allows a short and convenient preparation of glycosylated cationic lipids for gene delivery.
authors.affiliation: Laboratoire de Chimie Bioorganique et de Biotechnologie Moléculaire et Cellulaire. UMR 7001 CNRS-ENSCP-Aventis-Gencell. 11, rue Pierre et Marie Curie, 75231 Cedex, Paris, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Jacopin
authors.forename: Marie-José
authors.initials: MJ
authors.lastname: Egron
authors.forename: Daniel
authors.initials: D
authors.lastname: Scherman
authors.forename: Jean
authors.initials: J
authors.lastname: Herscovici
mesh_terms: D002412:Cations / Q000138:chemical synthesis / Q000737:chemistry; D006017:Glycolipids / Q000138:chemical synthesis* / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry*; D006031:Glycosylation; D008055:Lipids / Q000737:chemistry; D011073:Polyamines / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D002412:Cations; D006017:Glycolipids; D006027:Glycosides; D008055:Lipids; D011073:Polyamines