title: Giant inflammatory polyposis of the descending colon associated with a Crohn's disease-like colitis.
abstract: A case of giant inflammatory polyposis associated with a localized inflammatory bowel disease of the descending colon in a 49-year-old man is presented. Lower abdominal distension rapidly appeared without any previous history of gastrointestinal disease. Two months later, he underwent a left hemicolectomy. Postoperative recovery was complete and he remains in good health more than 2 years later. The resected colon showed a giant and bizarre polyposis measuring up to 12 cm in length and 2 cm in height and covering the entire circumference of the colon. The polyposis consisted of narrow worm- or noodle-like polyps that bridged over the irregularly shaped ulcers, which sometimes extended into muscularis propria. Although longitudinal ulcers or scars, stricture, and a cobble-stone appearance were not observed, transmural inflammation and deep fissures were found in the interpolypoid area. From these findings, this case seems to be more similar to Crohn's disease than other inflammatory bowel diseases.
authors.affiliation: Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan. kos180@tm.hama-med.ac.jp
authors.forename: Isao
authors.initials: I
authors.lastname: Kosugi
authors.forename: Toyohiro
authors.initials: T
authors.lastname: Tada
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Tsutsui
authors.forename: Yoko
authors.initials: Y
authors.lastname: Sato
authors.forename: Takamori
authors.initials: T
authors.lastname: Mitsui
authors.forename: Ippei
authors.initials: I
authors.lastname: Itazu
mesh_terms: D003092:Colitis / Q000209:etiology / Q000473:pathology*; D003106:Colon / Q000473:pathology* / Q000601:surgery; D003110:Colonic Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D003111:Colonic Polyps / Q000150:complications / Q000473:pathology* / Q000601:surgery; D003424:Crohn Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome