title: Monitoring of environmental UV radiation by biological dosimeters.
abstract: As a consequence of the stratospheric ozone layer depletion biological systems can be damaged due to increased UV-B radiation. The aim of biological dosimetry is to establish a quantitative basis for the risk assessment of the biosphere. DNA is the most important target molecule of biological systems having special sensitivity against short wavelength components of the environmental radiation. Biological dosimeters are usually simple organisms, or components of them, modeling the cellular DNA. Phage T7 and polycrystalline uracil biological dosimeters have been developed and used in our laboratory for monitoring the environmental radiation in different radiation conditions (from the polar to equatorial regions). Comparisons with Robertson-Berger (RB) meter data, as well as with model calculation data weighted by the corresponding spectral sensitivities of the dosimeters are presented. Suggestion is given how to determine the trend of the increase in the biological risk due to ozone depletion.
authors.affiliation: Institute of Biophysics, Semmelweis University of Medicine, Budapest, Hungary.
authors.forename: G
authors.initials: G
authors.lastname: Ronto
authors.forename: A
authors.initials: A
authors.lastname: Berces
authors.forename: P
authors.initials: P
authors.lastname: Grof
authors.forename: A
authors.initials: A
authors.lastname: Fekete
authors.forename: T
authors.initials: T
authors.lastname: Kerekgyarto
authors.forename: S
authors.initials: S
authors.lastname: Gaspar
authors.forename: C
authors.initials: C
authors.lastname: Stick
mesh_terms: D017123:Bacteriophage T7 / Q000528:radiation effects*; D004247:DNA / Q000528:radiation effects; D004249:DNA Damage; D005858:Germany; D006115:Greece; D006814:Hungary; D008954:Models, Biological; D009549:Nigeria; D010126:Ozone; D010507:Periodicity; D011740:Pyrimidine Dimers; D011834:Radiation Monitoring / Q000295:instrumentation / Q000379:methods*; D013472:Sunlight; D014466:Ultraviolet Rays; D014498:Uracil / Q000528:radiation effects*
chemical_list: D011740:Pyrimidine Dimers; D014498:Uracil; D010126:Ozone; D004247:DNA