Genotypic analysis by 27A DNA fingerprinting of Candida albicans strains isolated during an outbreak in a neonatal intensive care unit.
We describe an outbreak of Candida albicans systemic infection involving five premature infants in a neonatal intensive care unit. Molecular and epidemiologic characterization of all C. albicans isolates was performed by DNA fingerprinting with the 27A probe. This genotypic analysis demonstrated that the isolates were identical, providing evidence for the circulation of a unique C. albicans strain.
Boccia
Stefania
S
Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy.
Posteraro
Brunella
B
La Sorda
Marilena
M
Vento
Giovanni
G
Matassa
Piero Giuseppe
PG
Tempera
Alessia
A
Petrucci
Stefano
S
Fadda
Giovanni
G
D000046:Academic Medical Centers; D002176:Candida albicans / Q000145:classification / Q000235:genetics*; D002177:Candidiasis / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D016172:DNA Fingerprinting / Q000379:methods*; D004271:DNA, Fungal / Q000235:genetics*; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D005838:Genotype; D016519:Hospitals, Religious; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000453:epidemiology / Q000382:microbiology*; D019102:Infant, Very Low Birth Weight; D017053:Infection Control; D007363:Intensive Care Units, Neonatal; D017720:Molecular Epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012384:Rome / Q000453:epidemiology
D004271:DNA, Fungal