title: Measles in Thai adults: three case reports and management of contact cases.
abstract: We report on three adults (one nurse and two medical students) diagnosed as having measles. All the patients presented with fever, cough, conjunctival injection and rash. They contracted measles from pediatric patients who had been treated at Chulalongkorn Hospital in the previous two weeks. Physical examination revealed Koplik's spots on the oral mucosa and typical maculopapular rash. The diagnosis was confirmed by viral isolation. Measles IgG antibodies were measured in 36 medical students who were in close contact with patient 2 and measles vaccines were given. Thirty-three specimens had positive measles IgG, two had equivocal results and one had negative result. The student with negative measles IgG eventually developed measles (patient 3). Except for patient 2 and 3, no further cases of measles were seen among the contacts.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. chitsanu.p@chula.ac.th
authors.forename: C
authors.initials: C
authors.lastname: Pancharoen
authors.forename: S
authors.initials: S
authors.lastname: Wachirarojpaisan
authors.forename: S
authors.initials: S
authors.lastname: Pattamadilok
authors.forename: S
authors.initials: S
authors.lastname: Likitnukul
authors.forename: U
authors.initials: U
authors.lastname: Thisyakorn
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000302:isolation & purification; D016358:Contact Tracing; D005260:Female; D006801:Humans; D008297:Male; D008457:Measles / Q000175:diagnosis* / Q000276:immunology / Q000517:prevention & control; D008458:Measles Vaccine; D009726:Nurses; D010356:Patient Isolation; D013337:Students, Medical; D013785:Thailand
chemical_list: D000914:Antibodies, Viral; D008458:Measles Vaccine; C040901:rubella antibodies