title: The 3D's of apoptosis: death, degradation and DIAPs.
abstract: Inhibitor of apoptosis proteins (IAPs) are critical regulators of apoptosis. Recent evidence suggests that in some situations, induction of apoptosis initiates general repression of translation, as well as the targeted ubiquitination and degradation of IAPs.
authors.affiliation: Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA.
authors.forename: Tanapat
authors.initials: T
authors.lastname: Palaga
authors.forename: Barbara
authors.initials: B
authors.lastname: Osborne
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D029721:Drosophila Proteins / Q000378:metabolism*; D051034:Inhibitor of Apoptosis Proteins; D014176:Protein Biosynthesis / Q000502:physiology*; D025801:Ubiquitin / Q000378:metabolism
chemical_list: C111891:DIAP1 protein, Drosophila; D029721:Drosophila Proteins; D051034:Inhibitor of Apoptosis Proteins; D025801:Ubiquitin