title: Parasitenone, a new epoxycyclohexenone related to gabosine from the marine-derived fungus Aspergillus parasiticus.
abstract: Bioassay-guided fractionation of an organic extract of the broth from the marine-derived fungus culture of Aspergillus parasiticus led to the isolation and subsequent structural elucidation of a new gabosine derivative, parasitenone (1), and two known benzyl alcohols, 3-chloro-4,5-dihydroxybenzyl alcohol (2) and gentisyl alcohol (3). The benzyl alcohols (2, 3) were identified as the principal free radical scavenging components. Parasitenone (1) also showed moderate activity in the free radical scavenging assay.
authors.affiliation: Department of Chemistry, Pukyong National University, Busan 608-737, Korea. sonbw@pknu.ac.kr
authors.forename: Byeng Wha
authors.initials: BW
authors.lastname: Son
authors.forename: Jin Seok
authors.initials: JS
authors.lastname: Choi
authors.forename: Jung Chul
authors.initials: JC
authors.lastname: Kim
authors.forename: Ki Wan
authors.initials: KW
authors.lastname: Nam
authors.forename: Dong-Soo
authors.initials: DS
authors.lastname: Kim
authors.forename: Hae Young
authors.initials: HY
authors.lastname: Chung
authors.forename: Jung Sook
authors.initials: JS
authors.lastname: Kang
authors.forename: Hong Dae
authors.initials: HD
authors.lastname: Choi
mesh_terms: D000107:Acetylation; D001230:Aspergillus / Q000737:chemistry*; D001592:Benzyl Alcohols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D003512:Cyclohexanones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004852:Epoxy Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007723:Korea; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010084:Oxidation-Reduction; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D001592:Benzyl Alcohols; D003512:Cyclohexanones; D004852:Epoxy Compounds; D016166:Free Radical Scavengers; C461799:parasitenone