Focal epileptiform activity in the brain: detection with spike-related functional MR imaging--preliminary results.
The purpose of this study was to develop a spike-related functional magnetic resonance (MR) imaging method to detect epileptic brain activity. Correlations between simultaneous spike-related functional MR imaging and electroencephalographic (EEG) recordings were performed in 10 patients with focal epilepsy. Postprocessing techniques were implemented to eliminate contamination of the EEG recording from ballistocardiography and the echo-planar MR imaging sequence. A diagnostic EEG recording was achieved during functional MR imaging. Spike location correlated with the site of blood oxygen level-dependent signal increase. Spike-related functional MR imaging is a promising technique for detecting focal epileptic brain activity.
Jäger
Lorenz
L
Institute of Clinical Radiology, University of Munich, Klinikum Grosshadern, Marchioninistrasse 15, 81366 Munich, Germany. jaeger@ikra.med.uni-muenchen.de
Werhahn
Konrad J
KJ
Hoffmann
Alexander
A
Berthold
Sophia
S
Scholz
Verena
V
Weber
Jürgen
J
Noachtar
Soheyl
S
Reiser
Maximilian
M
D000328:Adult; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged