Influence of UV radiation and nitrosamines on the induction of mycotoxins synthesis by nontoxigenic moulds isolated from feed samples.
The effects of UV radiation and nitrosamines on the induction of mycotoxin biosynthesis by some nontoxigenic moulds isolated from feed samples collected from Egypt and Poland was investigated. Nontoxigenic strains of Aspergillus flavus P-63, A. niger EN-200 and A. ochraceus P-157 synthesized mycotoxins (aflatoxins and ochratoxin, A) after exposure to near UV radiation for 120-210 min. Nitrosamines (DMNA and DENA) at 30 up to 1000 ppm induced the synthesis of aflatoxins by nontoxigenic species of A. flavus ES-255 and P-63 and A. niger EN 200. Near-UV radiation and nitrosamines had no influence on the induction of mycotoxin synthesis by Penicillium and Fusarium isolates. All nontoxigenic strains of Aspergilli which synthesized aflatoxins in the presence of 1000 ppm nitrosamines, also synthesized continuously aflatoxins during the next fifteen generations. Near-UV radiation and nitrosamines had a mutagenic effect on the induction of mycotoxins synthesis by nontoxigenic moulds.
Aziz
Nagy H
NH
National Center for Radiation Research and Technology, 3 Ahmed El Zumor St., 8th Sector, P.O. Box 29, Nasr City, Cairo, 113701 Nasr City Cairo, Egypt.
Smyk
B
B
D001230:Aspergillus / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D005516:Food Microbiology; D005670:Fusarium / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D009183:Mycotoxins / Q000096:biosynthesis*; D009602:Nitrosamines / Q000494:pharmacology*; D010407:Penicillium / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D013997:Time Factors; D014466:Ultraviolet Rays
D009183:Mycotoxins; D009602:Nitrosamines