Tuberculosis in patients with myelodysplastic syndromes.
OBJECTIVE
The purpose of our study was to describe radiological manifestations of tuberculosis in patients with myelodysplastic syndromes.


METHODS
Chest radiographs and CTs of 12 patients with tuberculosis among 195 consecutive patients with myelodysplastic syndrome, proved by bone marrow biopsy, were reviewed. Six of the 12 patients presented with tuberculosis and were subsequently found to have myelodysplastic syndrome.


RESULTS
Chest radiographs and CTs revealed pulmonary tuberculosis in all 12 patients and extrapulmonary tuberculous involvement in six (50%). Initial chest radiographic findings of pulmonary tuberculosis included a primary pattern (n = 6), a post-primary pattern (n = 3), a miliary pattern (n = 1), atypical infiltrates (n = 1) and normal radiograph (n = 1). Tuberculosis involved extrathoracic lymph nodes (n = 5), liver (n = 2), spleen (n = 2), kidney (n = 2), bowel (n = 2), pericardium (n = 2) peritoneum (n = 1) and rib (n = 1).


CONCLUSIONS
Tuberculosis is a relatively common cause of infection in patients with myelodysplastic syndromes. The radiological appearance of pulmonary tuberculosis in myelodysplastic syndromes is often a primary pattern, and there is frequently extrapulmonary involvement.
Kim
Hyo-Cheol
HC
Department of Radiology, Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Korea.
Goo
Jin Mo
JM
Kim
Hyun Beom
HB
Lee
Joon Woo
JW
Seo
Joon Beom
JB
Im
Jung-Gi
JG
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging; D008297:Male; D008477:Mediastinal Diseases / Q000000981:diagnostic imaging; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000000981:diagnostic imaging* / Q000382:microbiology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014376:Tuberculosis / Q000150:complications / Q000000981:diagnostic imaging*; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging