[Study of thromboplastin sensitivity].
Comparative analysis of foreign and Russian thromboplastins demonstrated differences in the notions "activity" and "sensitivity" and the significance of low value of International Index of Sensitivity (IIS). Sensitivity of thromboplastin manufactured by RENAM Firm, Russia (IIS = 1.5) to deficiency of prothrombin factors II, VII, X has been demonstrated, which means that this thromboplastin can be used for diagnosis of deficiency of each of these factors. The authors consider that testing of thromboplastin sensitivity to factor VII is the main criterion of its fitness for monitoring anticoagulant therapy.
Kachalova
N D
ND
Prostakova
T M
TM
Kozlov
A A
AA
D000818:Animals; D006801:Humans; D011817:Rabbits; D012015:Reference Standards; D013925:Thromboplastin / Q000592:standards*
D013925:Thromboplastin