title: MRI for the evaluation of scleral invasion and extrascleral extension of uveal melanomas.
abstract: OBJECTIVE
  To study the diagnostic value of MRI for the detection of scleral infiltration and extrascleral extension of uveal melanoma.
  
  
  METHODS
  Twelve consecutive patients with clinically suspected large uveal melanoma were examined by MRI. All of the patients underwent enucleation or exenteration. The clinical and histopathological findings were compared.
  
  
  RESULTS
  The clinical diagnosis of uveal malignant melanoma was confirmed by histology in each case. MRI allowed detection of scleral infiltration with a sensitivity of 100% and a specificity of 50%. For extrascleral extension, MRI had a sensitivity of 100% and specificity of 89%.
  
  
  CONCLUSIONS
  Using fat suppression technique and enhancement with contrast medium, MRI proved to be a valuable ancillary method for the assessment of scleral infiltration and extrascleral extension.
authors.affiliation: Second Department of Ophthalmology, Faculty Medicine, Semmelweis University, Budapest, Hungary.
authors.forename: Zsuzsa
authors.initials: Z
authors.lastname: Récsán
authors.forename: Kinga
authors.initials: K
authors.lastname: Karlinger
authors.forename: Magdolna
authors.initials: M
authors.lastname: Fodor
authors.forename: Attila
authors.initials: A
authors.lastname: Zalatnai
authors.forename: Melitta
authors.initials: M
authors.lastname: Papp
authors.forename: György
authors.initials: G
authors.lastname: Salacz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005134:Eye Neoplasms / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000473:pathology*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011237:Predictive Value of Tests; D015422:Scleral Diseases / Q000473:pathology*; D012680:Sensitivity and Specificity; D014604:Uveal Neoplasms / Q000473:pathology*