title: Polarization oxygen sensor: a template for a class of fluorescence-based sensors.
abstract: We describe a novel oxygen polarization sensor based on a single molecule that changes the observed anisotropy of its emission with variation of the oxygen concentration. The approach is demonstrated both in solution and in solid films. A simple mathematical description of the sensor is included and experimentally verified. The technique demonstrated here creates opportunity for development of a new class of polarization-based dyes and sensors.
authors.affiliation: Department of Chemical and Biochemical Engineering, University of Maryland, Baltimore County, Baltimore 21250, USA.
authors.forename: Yordan
authors.initials: Y
authors.lastname: Kostov
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Gryczynski
authors.forename: Govind
authors.initials: G
authors.lastname: Rao
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D002138:Calibration; D005454:Fluorescence Polarization / Q000295:instrumentation; D010100:Oxygen / Q000032:analysis*
chemical_list: D010100:Oxygen