Dual activity of fluoroquinolones against Streptococcus pneumoniae: the facts behind the claims.
Smith
Heather J
HJ
Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Manitoba, Canada. smithhj14@hotmail.com
Nichol
Kimberly A
KA
Hoban
Daryl J
DJ
Zhanel
George G
GG
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D027081:DNA Gyrase / Q000235:genetics / Q000378:metabolism; D027101:DNA Topoisomerase IV / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004791:Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D024841:Fluoroquinolones; D006801:Humans; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D059005:Topoisomerase II Inhibitors
D000890:Anti-Infective Agents; D004791:Enzyme Inhibitors; D024841:Fluoroquinolones; D059005:Topoisomerase II Inhibitors; D027101:DNA Topoisomerase IV; D027081:DNA Gyrase