[Treatment with fluvoxamine against self-injury and aggressive behavior in autistic children].
Five autistic children underwent fluovoxamine administration. Their self-injury and aggressive behaviors did not respond psychotherapy and other medication with haloperidol, carbamazepine. The improvement of the behaviors was excellent in two patients, and partial in one patient. In a patient who received a combination of haloperidol and fluvoxamine, fluvoxamine treatment was discontinued because of severe drowsiness and could not continue. The other patients showed no obvious side effects. These results suggest that fluvoxamine treatment may be indicated for self-injury and aggressive behaviors in autistic children.
Yokoyama
Hiroyuki
H
Department of Pediatrics, Tohoku University School of Medicine, Sendai, Miyagi.
Hirose
Mieko
M
Haginoya
Kazuhiro
K
Munakata
Mitsutoshi
M
Iinuma
Kazuie
K
D000374:Aggression / Q000187:drug effects*; D001321:Autistic Disorder / Q000523:psychology*; D002648:Child; D002652:Child Behavior / Q000187:drug effects*; D002675:Child, Preschool; D016666:Fluvoxamine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016728:Self-Injurious Behavior / Q000188:drug therapy*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
D016666:Fluvoxamine; D017367:Selective Serotonin Reuptake Inhibitors