Full remission of tardive dyskinesia following general anaesthesia.
A 44 year old woman with a severe drug induced tardive dyskinesia had previously been treated with a left thalamotomy and right deep brain stimulation. Thalamotomy abolished the right hemiballismus. Deep brain stimulation caused a moderate reduction of the remaining involuntary movements on the left side. After a minor orthopaedic operation under general anaesthesia, the dyskinesia disappeared completely, even with the deep brain stimulation turned off. The remission has now lasted for 41 months.
Johnsen
Mads
M
Department of Neurosurgery, Haukeland University Hospital, 5021 Bergen, Norway.
Wester
Knut
K
D000328:Adult; D000732:Androstanols / Q000627:therapeutic use; D018681:Anesthetics, General / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology / Q000601:surgery; D004409:Dyskinesia, Drug-Induced / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D005265:Femoral Neck Fractures / Q000601:surgery; D005283:Fentanyl / Q000627:therapeutic use; D005475:Flupenthixol / Q000009:adverse effects*; D006801:Humans; D007530:Isoflurane / Q000627:therapeutic use; D019635:Neurosurgical Procedures; D011954:Receptors, Dopamine / Q000187:drug effects / Q000378:metabolism; D012074:Remission Induction / Q000379:methods; D000077123:Rocuronium; D013788:Thalamus / Q000601:surgery; D013874:Thiopental / Q000627:therapeutic use
D000732:Androstanols; D018681:Anesthetics, General; D014150:Antipsychotic Agents; D011954:Receptors, Dopamine; D007530:Isoflurane; D005475:Flupenthixol; D013874:Thiopental; D005283:Fentanyl; D000077123:Rocuronium