title: [A new practical route to stereospecific synthesis of (S)-(-)-ofloxacin].
abstract: (S)-(-)-ofloxacin is one of the best fluoroquinolone agents in current clinical use. A new facile practical route with good yield and high optical purity to stereospecific synthesis of (S)-(-)-ofloxacin was described.
authors.affiliation: Shanghai Institute of Materia Medica, Shanghai 200031.
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: R
authors.initials: R
authors.lastname: Ji
authors.forename: Z
authors.initials: Z
authors.lastname: Hu
authors.forename: K
authors.initials: K
authors.lastname: Chen
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D015242:Ofloxacin / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D000890:Anti-Infective Agents; D015242:Ofloxacin