New sesquiterpenes from Ferula ferulaeoides (Steud.) Korovin. VI. Isolation and identification of three new dihydrofuro[2,3-b]chromones.
Three novel 2-prenyl-dihydrofurochromone-type sesquiterpenoid derivatives, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4,8-dimethyl-3(E),7-nonadienyl]-furo[2,3-b]chromone, 2,3-dihydro-7-hydroxy-2S*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E),7-pentenyl]-furo[2,3-b]chromone, and 2,3-dihydro-7-hydroxy-2R*,3R*-dimethyl-2-[4-methyl-5-(4-methyl-2-furyl)-3(E),7-pentenyl]-furo[2,3-b]chromone, were isolated from the roots of Ferula ferulaeoides. The structures were established by comprehensive spectral analysis. The biosynthetic pathway leading to these 2-prenyl-dihydrofurochromone-type sesquiterpenoids is proposed based on their structures.
Nagatsu
Akito
A
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
Isaka
Kimio
K
Kojima
Keisuke
K
Ondognii
Purev
P
Zevgeegiin
Oyun
O
Gombosurengyin
Purevsuren
P
Davgiin
Khishgee
K
Irfan
Baig
B
Iqubal
Choudhary Muhammad
CM
Ogihara
Yukio
Y
D001209:Asia, Central; D002867:Chromones / Q000737:chemistry* / Q000302:isolation & purification; D005309:Ferula / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008986:Mongolia; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry*
D002867:Chromones; D012717:Sesquiterpenes