title: Tumor-associated tissue eosinophilia of penile cancer.
abstract: BACKGROUND
  Tumor-associated tissue eosinophilia (TATE) occurs in many kinds of cancer. This study analyzed whether TATE improves the survival of penile cancer patients.
  
  
  METHODS
  In 17 patients with penile cancer, survival was compared between the TATE-positive group and the TATE-negative group. Tissue eosinophils were observed by transmission electron microscopy.
  
  
  RESULTS
  In all cases, 5-year survival was 72.9% in the TATE-positive group (n = 8) and 38.9% in the TATE-negative group (n = 9; P = 0.131). In stage III and IV, it was 60% in the TATE-positive group (n = 5) and 0% in the TATE-negative group (n = 5; P = 0.058). Transmission electron microscopy images revealed the vigorous infiltration of tissue eosinophils.
  
  
  CONCLUSIONS
  It is suggested that TATE improves the survival of patients with advanced penile cancer. However, a greater number of subjects is needed to prove statistical significance.
authors.affiliation: Department of Urology, Gunma Cancer Center, Gunma University, School of Medicine, Japan. yoshi@econett.co.jp
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Ono
authors.forename: Masashi
authors.initials: M
authors.lastname: Ozawa
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Tamura
authors.forename: Takanori
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Suzuki
authors.forename: Kohei
authors.initials: K
authors.lastname: Kurokawa
authors.forename: Yoshitatsu
authors.initials: Y
authors.lastname: Fukabori
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Yamanaka
mesh_terms: D004802:Eosinophilia / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D010412:Penile Neoplasms / Q000150:complications / Q000401:mortality* / Q000473:pathology; D015996:Survival Rate