[The routine coagulation tests along with activated protein C resistance (APC-R) in population of women applying for oral contraceptives].
The routine coagulation tests along with activated protein C resistance (APC-R) were studied in North-Eastern Poland women, applying for oral contraceptives. The APTT, PT and fibrinogen concentration were evaluated in 128 women, aged 20-40 years, by means of nephelometric method. For estimation of APC-R, Coatest APC Resistance V test was used. The abnormalities in routine coagulation test were found in 13.3% of studied women. The resistance to activated protein C was observed among 4.3% of women with normal results of routine coagulation tests. The thrombotic event occurred in one of five APC-R positive woman. There was no correlation between APC-V ratio and APTT, PT or fibrinogen values.
Kostecka
I
I
Zakład Diagnostyki Hematologicznej Samodzielny Publiczny Szpital Kliniczny Akademii Medycznej w Białymstoku.
Dabrowska
M
M
Osada
J
J
Suchowierska
M
M
Wołczyński
S
S
D020016:Activated Protein C Resistance / Q000097:blood* / Q000175:diagnosis*; D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects*; D001780:Blood Coagulation Tests; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011044:Poland; D012307:Risk Factors; D012680:Sensitivity and Specificity
D003278:Contraceptives, Oral, Hormonal