Cytokinesis: regulated by destruction.
Important transitions in the cell cycle are regulated by ubiquitin-dependent degradation of specific proteins. Recent data indicate that cytokinesis is also regulated by proteolysis.
Glotzer
Michael
M
Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030, Vienna, Austria. mglotzer@nt.imp.univie.ac.at
Dechant
Reinhard
R
D064173:Anaphase-Promoting Complex-Cyclosome; D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D002455:Cell Division; D020090:Chromosome Segregation; D004625:Embryo, Nonmammalian / Q000166:cytology* / Q000378:metabolism*; D008025:Ligases / Q000378:metabolism; D008938:Mitosis; D012617:Sea Urchins / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D008941:Spindle Apparatus / Q000378:metabolism; D025801:Ubiquitin / Q000378:metabolism*; D043743:Ubiquitin-Protein Ligase Complexes
D025801:Ubiquitin; D043743:Ubiquitin-Protein Ligase Complexes; D064173:Anaphase-Promoting Complex-Cyclosome; D008025:Ligases