title: D2-lymphadenectomy improves the survival of patients with peritoneal cytology-positive gastric cancer.
abstract: BACKGROUND
  According to the current Japanese Classification of Gastric Cancer, patients with peritoneal cytology-positive (CY1) gastric cancer are classified as stage IV and the curative potential of resection for these patients is regarded as non-curative.
  
  
  METHODS
  We compared the clinical outcome of CY1 patients (n=55) with those of patients with other non-curative factors (n=87), to clarify the optimal surgical strategy for CY1 patients.
  
  
  RESULTS
  The 5-year survival rate of CY1 patients was 10.8%, which was significantly better than that observed in the patients with the other non-curative factors. Among CY1 cases, survival outcome of the patients with lymph node metastasis limited to within group 2 was significantly better than the patients with group 3 lymph node metastasis.
  
  
  CONCLUSIONS
  These results suggested that gastrectomy combined with extended lymphadenectomy should be recommended for patients with gastric cancer who have positive peritoneal cytology as the only non-curative factor.
authors.affiliation: Department of Surgery, Tochigi Cancer Center, Utsunomiya, Japan. tinada@tcc.pref.tochigi.jp
authors.forename: Takao
authors.initials: T
authors.lastname: Inada
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Ogata
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Kubota
authors.forename: Masami
authors.initials: M
authors.lastname: Ishihara
authors.forename: Moriaki
authors.initials: M
authors.lastname: Tomikawa
authors.forename: Jiro
authors.initials: J
authors.lastname: Ando
authors.forename: Iwao
authors.initials: I
authors.lastname: Ozawa
authors.forename: Shoichi
authors.initials: S
authors.lastname: Hishinuma
authors.forename: Hideaki
authors.initials: H
authors.lastname: Shimizu
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Kotake
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010529:Peritoneal Cavity / Q000473:pathology*; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome