title: 5-Bromo-2'-deoxyuridine efficiently suppresses division potential of the yeast Saccharomyces cerevisiae.
abstract: We established a thymidine-auxotrophic strain of the yeast Saccharomyces cerevisiae to examine biological effects of thymidine analogues. 5-Bromo-2'-deoxyuridine efficiently suppressed the division potential of yeast showing morphology similar to senescent cells.
authors.affiliation: Division of Biochemistry, Kihara Institute for Biological Research and Graduate School of Integrated Science, Yokohama City University, Yokohama, Japan.
authors.forename: Michihiko
authors.initials: M
authors.lastname: Fujii
authors.forename: Hisasi
authors.initials: H
authors.lastname: Ito
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Suzuki
authors.forename: Noritaka
authors.initials: N
authors.lastname: Adachi
authors.forename: Dai
authors.initials: D
authors.lastname: Ayusawa
mesh_terms: D001973:Bromodeoxyuridine / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D007700:Kinetics; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000187:drug effects / Q000254:growth & development*; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors
chemical_list: D001973:Bromodeoxyuridine; D013936:Thymidine