Hydrodynamics of magnetic drug targeting.
Among the proposed techniques for delivering drugs to specific locations within the human body, magnetic drug targeting surpasses due to its non-invasive character and its high targeting efficiency. Although the method has been proposed almost 30 years ago, the technical problems obstruct possible applications. It is the aim of the present work to classify the emerging problems and propose satisfactory answers. A general phenomenological theory is developed and a model case is studied, which incorporates all the physical parameters of the problem.
Voltairas
P A
PA
Department of Computer Science, University of Ioannina, Ioannina 451 10, Greece. pvolter@cs.uoi.gr
Fotiadis
D I
DI
Michalis
L K
LK
D001672:Biocompatible Materials; D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000502:physiology; D003198:Computer Simulation; D004337:Drug Carriers; D016503:Drug Delivery Systems; D005263:Femoral Artery / Q000502:physiology; D018056:Hemorheology / Q000379:methods*; D008280:Magnetics; D008863:Microspheres; D008955:Models, Cardiovascular; D012680:Sensitivity and Specificity; D000267:Tissue Adhesions
D001672:Biocompatible Materials; D004337:Drug Carriers