Recent advances in hormonal male contraception.
Hormones inhibit fertility in men by suppressing sperm production. Testosterone-enanthate induced azoospermia has proven to provide optimal contraceptive protection. Preliminary studies have shown that testosterone alone or androgen-progestin combinations induce profound sperm suppression in the Eastern and white populations, respectively. Thus, these regimens may represent viable options for male contraception. New long-acting androgen formulations represent a major advancement in this field, allowing for the development of more acceptable and effective regimens.
Meriggiola
M C
MC
Clinic of Obstetrics and Gynecology, S. Orsola-Malpighi Hospital, University of Bologna, Italy. crismeri@med.unibo.it
Costantino
A
A
Cerpolini
S
S
D000728:Androgens / Q000008:administration & dosage; D000988:Antispermatogenic Agents / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D003272:Contraceptive Agents, Male / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D008297:Male; D011372:Progestins / Q000008:administration & dosage; D013091:Spermatogenesis / Q000187:drug effects; D013739:Testosterone / Q000008:administration & dosage
D000728:Androgens; D000988:Antispermatogenic Agents; D003272:Contraceptive Agents, Male; D011372:Progestins; D013739:Testosterone