title: A genome-activating N-terminal coat protein peptide of alfalfa mosaic virus is able to activate infection by RNAs 1, 2 and 3 but not by RNAs 1 and 2. Further support for the messenger release hypothesis.
abstract: An N-terminal genome-activating peptide of 25 amino acid residues of alfalfa mosaic virus coat protein was unable to activate the incomplete viral genome consisting of RNAs 1 and 2. The messenger release hypothesis predicts that RNA 3 must complement such an inoculum in order to produce RNA 4 that will trigger the process. This is shown indeed to be the case.
authors.affiliation: Institute of Molecular Plant Sciences, Gorlaeus Laboratories, Leiden University, The Netherlands.
authors.forename: E M J
authors.initials: EM
authors.lastname: Jaspars
authors.forename: C J
authors.initials: CJ
authors.lastname: Houwing
mesh_terms: D017794:Alfalfa mosaic virus / Q000235:genetics / Q000502:physiology*; D000595:Amino Acid Sequence; D002213:Capsid / Q000737:chemistry / Q000378:metabolism*; D036022:Capsid Proteins; D016679:Genome, Viral; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis / Q000378:metabolism; D010935:Plant Diseases / Q000821:virology*; D011485:Protein Binding; D011523:Protoplasts / Q000821:virology; D012333:RNA, Messenger / Q000032:analysis; D012367:RNA, Viral / Q000737:chemistry / Q000378:metabolism*; D014779:Virus Replication
chemical_list: D036022:Capsid Proteins; D010455:Peptides; D012333:RNA, Messenger; D012367:RNA, Viral; C095691:coat protein, Alfalfa mosaic virus