Myelopathy in primary Sjögren's syndrome: diagnostic and therapeutic aspects.
We report a patient with a myelopathy in primary Sjögren's syndrome, proven by salivary gland biopsy and specific antibodies. Under steroid medication, the patient had a remitting and relapsing clinical course. The severity of clinical symptoms correlated with a transient contrast uptake in spinal magnetic resonance imaging. Under a treatment with azathioprine and prednisone the patient has suffered no relapse within the last 20 months. Although this is only a case report, the combination of azathioprine and prednisone may be a valuable medication in chronic cases of Sjögren's syndrome with neurologic symptoms.
Hermisson
M
M
Department of Neurology, University of Tübingen Medical School, Germany.
Klein
R
R
Schmidt
F
F
Weller
M
M
Küker
W
W
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001379:Azathioprine / Q000008:administration & dosage; D001706:Biopsy; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D007223:Infant; D008279:Magnetic Resonance Imaging; D011239:Prednisolone / Q000008:administration & dosage; D012859:Sjogren's Syndrome / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D013118:Spinal Cord Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D011239:Prednisolone; D001379:Azathioprine