title: [Allele distribution at the HVR-IgH hypervariable locus in unrelated individuals living in the Ural, Siberia, and northern Kazakhstan].
abstract: Allelic polymorphism at a hypervariable locus mapped to the 5'-region of the gene cluster encoding JH segments of human immunoglobulin heavy chain H (IgH-VNTR) was typed in 462 unrelated individuals living in the Urals, Siberia, and Northern Kazakhstan. Molecular characteristics of the three previously unknown IgH-VNTR alleles is presented. The observed genotype frequencies were concordant with those expected under the Hardy-Weinberg distribution. The data obtained can be used in the work of regional forensic laboratories.
authors.affiliation: Regional Forensic Bureau, Novosibirsk, 630087 Russia.
authors.forename: I A
authors.initials: IA
authors.lastname: Bin'ko
authors.forename: D A
authors.initials: DA
authors.lastname: Shorokhova
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Shvarts
authors.forename: S A
authors.initials: SA
authors.lastname: Demakov
authors.forename: V P
authors.initials: VP
authors.lastname: Novoselov
mesh_terms: D000483:Alleles; D001483:Base Sequence; D001486:Bashkiria; D014644:Genetic Variation; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D007623:Kazakhstan; D008969:Molecular Sequence Data; D012800:Siberia; D020080:Tandem Repeat Sequences
chemical_list: D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region