title: Acinic cell carcinoma of the sublingual gland accompanied by bone formation.
abstract: A rare case of acinic cell carcinoma of the sublingual gland accompanied by bone formation is reported. The patient is a 79-year-old male who was referred to Yokohama Minami Kyosai Hospital with sublingual swelling. A tumor mass, 20 x 10 mm in diameter, was detected on the right side of the floor of the mouth. Computed tomography (CT) revealed a mass lesion with calcification in the sublingual gland. The patient underwent total sialadenectomy of the sublingual gland with conservation of the lingual nerve. Histologically, the lesion showed amylase-positive atypical cells with thyroid gland-like arrangement, and mature bone tissue in the stroma. Based on these findings, the tumor was diagnosed as acinic cell carcinoma accompanied by bone formation. Postoperative recovery was uneventful, and two years after surgery, there are no signs of distant metastases or recurrence.
authors.affiliation: Department of Oral Surgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan. yota@is.icc.u-tokai.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Ota
authors.forename: I
authors.initials: I
authors.lastname: Arai
authors.forename: T
authors.initials: T
authors.lastname: Aoki
authors.forename: H
authors.initials: H
authors.lastname: Yamazaki
authors.forename: K
authors.initials: K
authors.lastname: Karakida
authors.forename: K
authors.initials: K
authors.lastname: Tsukinoki
mesh_terms: D000368:Aged; D018267:Carcinoma, Acinar Cell / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D010012:Osteogenesis; D013362:Sublingual Gland Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed