title: Autoimmune thyroiditis in infants with Down's syndrome.
abstract: Children with Down's syndrome are at high risk of thyroid dysfunction, including autoimmune thyroiditis. We describe two infants with Down's syndrome in whom chronic autoimmune thyroiditis was diagnosed at ages 5 months and 8 months. We suggest that follow-up of thyroid function and thyroid autoantibodies should be started from infancy in Down's syndrome to prevent further deterioration of mental development and growth.
authors.affiliation: Institute of Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah Tiqva. shalitin@netvision.net.il
authors.forename: Shlomit
authors.initials: S
authors.lastname: Shalitin
authors.forename: Moshe
authors.initials: M
authors.lastname: Phillip
mesh_terms: D001323:Autoantibodies / Q000097:blood; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013961:Thyroid Gland / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use
chemical_list: D001323:Autoantibodies; D013972:Thyrotropin; D013974:Thyroxine