Hepatitis C virus related cryoglobulinemic glomerulonephritis.
A 46 years male presented with skin rash and acute nephritic syndrome. He had history of jaundice four months back. Rheumatoid factor and cryoglobulins were present in the serum. Although anti-HCV antibodies were negative, HCV RNA was detected by polymerase chain reaction. Kidney biopsy showed membranoproliferative glomerulonephritis and thrombi in the lumen of the glomerular capillary loops. His renal functions improved with steroids.
Bhowmik
D
D
Department of Nephrology, All India Institute of Medical Sciences, New Delhi.
Padmanabhan
S
S
Dinda
A
A
Modi
G
G
Gupta
S
S
Agarwal
S K
SK
Tiwari
S C
SC
Dash
S C
SC
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D003449:Cryoglobulinemia / Q000188:drug therapy / Q000209:etiology*; D005500:Follow-Up Studies; D015432:Glomerulonephritis, Membranoproliferative / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D016174:Hepacivirus / Q000235:genetics; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012367:RNA, Viral / Q000032:analysis; D013997:Time Factors
D000893:Anti-Inflammatory Agents; D012367:RNA, Viral; D011239:Prednisolone