title: Treatment of canine lymphoma by veterinarians in first opinion practice in England.
abstract: A survey of canine lymphoma treatment strategies by veterinarians in first opinion practice was undertaken by sending questionnaires to 1000 randomly selected, first opinion small animal veterinary practices throughout England. Completed replies were received from 382 veterinarians. Ninety-five per cent of respondents had diagnosed canine lymphoma in the preceding 12 months. Eighty-seven per cent of respondents treated at least 50 per cent of the cases of canine lymphoma they diagnosed. A multidrug combination of vincristine, cyclophosphamide and prednisolone (COP) was the treatment protocol most commonly used. A doxorubicin-based treatment protocol was used by 2 per cent of respondents to treat canine lymphoma initially. The study suggests that, despite several reports of improved survival times with doxorubicin-based protocols, most veterinarians in first opinion practice in England treat canine lymphoma with COP.
authors.affiliation: Queen's Veterinary School Hospital, University of Cambridge.
authors.forename: R J
authors.initials: RJ
authors.lastname: Mellanby
authors.forename: M E
authors.initials: ME
authors.lastname: Herrtage
authors.forename: J M
authors.initials: JM
authors.lastname: Dobson
mesh_terms: D000328:Adult; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004317:Doxorubicin / Q000008:administration & dosage; D004739:England; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D011239:Prednisolone / Q000008:administration & dosage; D011379:Prognosis; D014730:Veterinary Medicine / Q000706:statistics & numerical data*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone