title: HIV-1 subtypes in Yugoslavia.
abstract: To gain insight concerning the genetic diversity of HIV-1 viruses associated with the HIV-1 epidemic in Yugoslavia, 45 specimens from HIV-1-infected individuals were classified into subtypes by sequence-based phylogenetic analysis of the polymerase (pol) region of the viral genome. Forty-one of 45 specimens (91.2%) were identified as pol subtype B, 2 of 45 as subtype C (4.4%), 1 of 45 as CRF01_AE (2.2%), and 1 as CRF02_AG recombinant (2.2%). Nucleotide divergence among subtype B sequences was 4.8%. Results of this study show that among HIV-1-infected patients in Yugoslavia subtype B predominates (91.5%), whereas non-B subtypes are present at a low percentage, mostly related to travel abroad.
authors.affiliation: Institute of Microbiology and Immunology, Medical School, University of Belgrade, DrSubotica 1, 11000 Belgrade, Yugoslavia. nasta@eunet.yu
authors.forename: Maja
authors.initials: M
authors.lastname: Stanojevic
authors.forename: Anna
authors.initials: A
authors.lastname: Papa
authors.forename: Evagelia
authors.initials: E
authors.lastname: Papadimitriou
authors.forename: Sonja
authors.initials: S
authors.lastname: Zerjav
authors.forename: Djordje
authors.initials: D
authors.lastname: Jevtovic
authors.forename: Dubravka
authors.initials: D
authors.lastname: Salemovic
authors.forename: Tanja
authors.initials: T
authors.lastname: Jovanovic
authors.forename: Antonis
authors.initials: A
authors.lastname: Antoniadis
mesh_terms: D000328:Adult; D001483:Base Sequence; D005260:Female; D015684:Gene Products, pol / Q000235:genetics*; D014644:Genetic Variation; D015658:HIV Infections / Q000821:virology; D015497:HIV-1 / Q000145:classification* / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D010802:Phylogeny; D011995:Recombination, Genetic; D015022:Yugoslavia
chemical_list: D015684:Gene Products, pol