[Hormone therapies in pregnancy].
Maternal endocrine disorders can have detrimental effects on the fetus and the pregnancy can affect the course of a pre-exisiting endocrinopathy or induce the onset of one of these disorders. Therapies for endocrine disorders are not always safe to administer during pregnancy. Before administering any therapy to the mother, the effects on the fetus, the degree of placental trespassing as well as the potential damaging effects must be assessed. An accurate evaluation of the risks/benefits of any drug to be used on the mother is needed, assessing above all a potential theratogenic effect. In this review, the incidence of the main endocrine disorders, their evolution during pregnancy, their effects on mothers and fetuses and new acquisition on the treatment during pregnancy are discussed.
Tommaselli
G A
GA
Dipartimento di Ginecologia, Ostetricia e Fisiopatologia della Riproduzione Umana, Università degli Studi di Napoli, Federico II, Napoli, Italy.
Pellicano
M
M
Guida
M
M
Palomba
S
S
Savarese
F
F
Nola
B
B
Ferrara
C
C
Lapadula
C
C
Nappi
C
C
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000172:Acromegaly / Q000188:drug therapy; D000224:Addison Disease / Q000188:drug therapy; D000328:Adult; D002648:Child; D003480:Cushing Syndrome / Q000188:drug therapy; D003919:Diabetes Insipidus / Q000188:drug therapy; D004700:Endocrine System Diseases / Q000188:drug therapy*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006728:Hormones / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy; D006961:Hyperparathyroidism / Q000188:drug therapy; D006980:Hyperthyroidism / Q000188:drug therapy; D007011:Hypoparathyroidism / Q000188:drug therapy; D007037:Hypothyroidism / Q000188:drug therapy; D007231:Infant, Newborn; D010911:Pituitary Neoplasms / Q000188:drug therapy / Q000601:surgery; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy / Q000601:surgery; D015175:Prolactinoma / Q000188:drug therapy / Q000601:surgery; D018570:Risk Assessment
D006728:Hormones