Clinical experience with human immunodeficiency virus-infected older patients in the era of effective antiretroviral therapy.
New therapies for human immunodeficiency virus (HIV)-infected patients suggest the need to examine whether these therapies are as effective in older patients as in younger patients. Fifty-two patients aged >/=50 years were compared with 52 patients aged <50 years for changes in CD4(+) counts, viral loads, opportunistic disease, hospitalizations, drug side effects, and death. No differences were found, except for higher rates of candidiasis in younger patients. Antiretroviral therapy seems to be equally effective in older and younger patients.
Grimes
Richard M
RM
Department of Management and Policy Sciences, School of Public Health, University of Texas-Houston Health Science Center, Houston, TX, 77225, USA. rgrimes@sph.uth.tmc.edu
Otiniano
Max E
ME
Rodriguez-Barradas
Maria C
MC
Lai
Dejian
D
D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged
D019380:Anti-HIV Agents