title: Typhoid fever in Malaysian children.
abstract: A prospective study of 102 children with bacteriologically confirmed typhoid fever, admitted to Hospital Universiti Sains Malaysia over 5 years was conducted. The average age at presentation was 91.3 (range 6 - 159) months. Fever (900%), abdominal pain (56%) and diarrhoea (44%) were common symptoms. Findings included: hepatomegaly (85.3%), splenomegaly (27.5%), anaemia (31%), leukopenia (15%). thrombocytopenia (26%), positive Widal (62.5%) and Typhidot test (96%). Patients were treated with ampicillin (n = 54) or chloramphenicol (n = 49) and 1/3 developed complications like hepatitis (n = 19), bone marrow suppression (n = 8) and paralytic ileus (n = 7). A patient with splenomegaly, thrombocytopenia or leukopenia was at higher risk of developing complications.
authors.affiliation: Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Kuching.
authors.forename: A S
authors.initials: AS
authors.lastname: Malik
authors.forename: R H
authors.initials: RH
authors.lastname: Malik
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D011446:Prospective Studies; D014435:Typhoid Fever / Q000150:complications / Q000453:epidemiology* / Q000628:therapy