title: Specific interactions of deprotonated carboxylic group with uracil and thymine provoke diketo-->keto-enol tautomeric transition in bases.
abstract: The 1H NMR and MNDO/H calculation data combined indicate the uracil and thymine tautomeric transitions from the ground diketo tautomeric state to the high-energy keto-enol one stimulated by specific interaction with carboxylate ion in anhydrous DMSO, which is blocked by base methylation at the 1 or 3 positions.
authors.affiliation: Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv.
authors.forename: S P
authors.initials: SP
authors.lastname: Samijlenko
authors.forename: I V
authors.initials: IV
authors.lastname: Kondratyuk
authors.forename: A L
authors.initials: AL
authors.lastname: Potyahaylo
authors.forename: A V
authors.initials: AV
authors.lastname: Stepanyugin
authors.forename: D M
authors.initials: DM
authors.lastname: Hovorun
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013816:Thermodynamics; D013941:Thymine / Q000737:chemistry*; D014498:Uracil / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D014498:Uracil; D013941:Thymine