title: Amniotic membrane graft for late-onset glaucoma filtering leaks.
abstract: OBJECTIVE
  To evaluate the effectiveness and safety of amniotic membrane graft in the management of late-onset filtering bleb leaks after trabeculectomy with mitomycin C.
  
  
  METHODS
  Prospective, noncomparative, interventional case reports.
  
  
  METHODS
  Two eyes of two patients with late-onset filtering bleb leak received an amniotic membrane graft.
  
  
  RESULTS
  In both patients, bleb leaks were closed successfully with amniotic membrane graft, and bleb function was maintained during the follow-up period of 34 and 14 months, respectively.
  
  
  CONCLUSIONS
  Amniotic membrane graft may be considered an alternative method for treating late-onset filtering bleb leaks while maintaining bleb function. As the number of cases was small, more cases need to be accumulated to verify the usefulness of this technique.
authors.affiliation: Department of Ophthalmology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea. cwkee@ophthalmology.org
authors.forename: Changwon
authors.initials: C
authors.lastname: Kee
authors.forename: Jeong-Min
authors.initials: JM
authors.lastname: Hwang
mesh_terms: D000328:Adult; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use; D011183:Postoperative Complications / Q000601:surgery*; D011446:Prospective Studies; D014130:Trabeculectomy / Q000009:adverse effects*; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D016685:Mitomycin