title: [Monthly cycles of 1-week therapy with itraconazole for patients with Tinea pedis].
abstract: Monthly cycles of 1-week therapy with oral itraconazole at 200 mg daily for tinea pedis was assessed to determine its acceptability to patients. Thirty-four patients (17 men and 17 women) with intractable tinea pedis, with informed consent, took 200 mg of itraconazole once daily for one week over a month period until mycological studies showed negative results for up to 4 months. The overall mycological effectiveness was about 80% after this therapy. Information was also gathered on the influence of this therapy on the patients quality of life by questionnaires. Nineteen (70%) among the 27 patients who answered the questionnaire preferred this 1-week administration of itraconazole over a month-long period compared with continuous daily therapy. Twenty-two (81%) preferred this therapy over topical treatment. We recommend to this therapy be added for the treatment of intractable tinea pedis.
authors.affiliation: Department of Dermatology, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Mizuno
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakanishi
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Fukai
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Ishii
authors.forename: Kensuke
authors.initials: K
authors.lastname: Morimoto
mesh_terms: D000284:Administration, Oral; D000935:Antifungal Agents / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D020551:Pulse Therapy, Drug; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014008:Tinea Pedis / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole