[Allele distribution at the HVR-IgH hypervariable locus in unrelated individuals living in the Ural, Siberia, and northern Kazakhstan].
Allelic polymorphism at a hypervariable locus mapped to the 5'-region of the gene cluster encoding JH segments of human immunoglobulin heavy chain H (IgH-VNTR) was typed in 462 unrelated individuals living in the Urals, Siberia, and Northern Kazakhstan. Molecular characteristics of the three previously unknown IgH-VNTR alleles is presented. The observed genotype frequencies were concordant with those expected under the Hardy-Weinberg distribution. The data obtained can be used in the work of regional forensic laboratories.
Bin'ko
I A
IA
Regional Forensic Bureau, Novosibirsk, 630087 Russia.
Shorokhova
D A
DA
Shvarts
Iu B
IuB
Demakov
S A
SA
Novoselov
V P
VP
D000483:Alleles; D001483:Base Sequence; D001486:Bashkiria; D014644:Genetic Variation; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D007135:Immunoglobulin Variable Region / Q000235:genetics*; D007623:Kazakhstan; D008969:Molecular Sequence Data; D012800:Siberia; D020080:Tandem Repeat Sequences
D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region