Role of amiodarone in reducing atrial fibrillation after cardiac surgery in adults.
Atrial fibrillation is a common occurrence after cardiac surgery and the source of financial expenditure and complications. A critical literature review was undertaken to examine the use of amiodarone therapy to prevent or manage atrial fibrillation after cardiac surgery. Evidence strongly suggests that perioperative treatment of cardiac patients with amiodarone may reduce the incidence of atrial fibrillation with minimal adverse effects. Further study is warranted to determine the optimal timing and dosing, for the drug's most cost-effective use.
Haan
Constance K
CK
The Cardiovascular Center of the University of Florida Health Science Center at Jacksonville, 32209, USA. connie.haan@jax.ufl.edu
Geraci
Stephen A
SA
D000328:Adult; D000638:Amiodarone / Q000009:adverse effects / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D001026:Coronary Artery Bypass; D004311:Double-Blind Method; D004341:Drug Evaluation; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D011183:Postoperative Complications / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic
D000638:Amiodarone