A case of Rosai-Dorfman disease involving the lacrimal gland in an elderly patient.
Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a rare disease characterised by benign proliferation of histiocytes, with painless lymph node enlargement and frequent extranodal involvement. Orbital involvement occurs in 11% of cases and onset of the disease is typically in the first two decades of life. A benign course is usual, but in some cases blindness or fatality may result. We present a case with late onset at age 78 years and lacrimal gland involvement, and review the literature on this disease.
Beckingsale
Peter
P
Eyelid, Lacrimal and Orbital Clinic, Royal Brisbane Hospital, Brisbane, QLD, Australia.
Sullivan
Timothy
T
Whitehead
Kevin
K
D000368:Aged; D005260:Female; D015618:Histiocytosis, Sinus / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed