title: [Treatment with fluvoxamine against self-injury and aggressive behavior in autistic children].
abstract: Five autistic children underwent fluovoxamine administration. Their self-injury and aggressive behaviors did not respond psychotherapy and other medication with haloperidol, carbamazepine. The improvement of the behaviors was excellent in two patients, and partial in one patient. In a patient who received a combination of haloperidol and fluvoxamine, fluvoxamine treatment was discontinued because of severe drowsiness and could not continue. The other patients showed no obvious side effects. These results suggest that fluvoxamine treatment may be indicated for self-injury and aggressive behaviors in autistic children.
authors.affiliation: Department of Pediatrics, Tohoku University School of Medicine, Sendai, Miyagi.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yokoyama
authors.forename: Mieko
authors.initials: M
authors.lastname: Hirose
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Haginoya
authors.forename: Mitsutoshi
authors.initials: M
authors.lastname: Munakata
authors.forename: Kazuie
authors.initials: K
authors.lastname: Iinuma
mesh_terms: D000374:Aggression / Q000187:drug effects*; D001321:Autistic Disorder / Q000523:psychology*; D002648:Child; D002652:Child Behavior / Q000187:drug effects*; D002675:Child, Preschool; D016666:Fluvoxamine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016728:Self-Injurious Behavior / Q000188:drug therapy*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
chemical_list: D016666:Fluvoxamine; D017367:Selective Serotonin Reuptake Inhibitors