title: Spectroscopic characterization of selected beta- sheet hairpin models.
abstract: The IR and vibrational circular dichroism (VCD) spectra of a model two-stranded beta hairpin are compared to those of a related cyclic two-stranded model, which are both stabilized by DPro- Gly turns. The spectra are compared to ab initio based simulations to support specific assignments of the dominant features and suggest a revised interpretation of the IR and VCD spectra for beta sheet containing proteins.
authors.affiliation: Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, 60607- 7061, USA.
authors.forename: Jovencio
authors.initials: J
authors.lastname: Hilario
authors.forename: Jan
authors.initials: J
authors.lastname: Kubelka
authors.forename: Faisal A
authors.initials: FA
authors.lastname: Syud
authors.forename: Samuel H
authors.initials: SH
authors.lastname: Gellman
authors.forename: Timothy A
authors.initials: TA
authors.lastname: Keiderling
mesh_terms: D002942:Circular Dichroism; D005799:Genes, Dominant; D010452:Peptide Biosynthesis; D010455:Peptides / Q000737:chemistry; D017433:Protein Structure, Secondary; D013055:Spectrophotometry, Infrared / Q000379:methods*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D010455:Peptides