title: Genotypic analysis by 27A DNA fingerprinting of Candida albicans strains isolated during an outbreak in a neonatal intensive care unit.
abstract: We describe an outbreak of Candida albicans systemic infection involving five premature infants in a neonatal intensive care unit. Molecular and epidemiologic characterization of all C. albicans isolates was performed by DNA fingerprinting with the 27A probe. This genotypic analysis demonstrated that the isolates were identical, providing evidence for the circulation of a unique C. albicans strain.
authors.affiliation: Institute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Boccia
authors.forename: Brunella
authors.initials: B
authors.lastname: Posteraro
authors.forename: Marilena
authors.initials: M
authors.lastname: La Sorda
authors.forename: Giovanni
authors.initials: G
authors.lastname: Vento
authors.forename: Piero Giuseppe
authors.initials: PG
authors.lastname: Matassa
authors.forename: Alessia
authors.initials: A
authors.lastname: Tempera
authors.forename: Stefano
authors.initials: S
authors.lastname: Petrucci
authors.forename: Giovanni
authors.initials: G
authors.lastname: Fadda
mesh_terms: D000046:Academic Medical Centers; D002176:Candida albicans / Q000145:classification / Q000235:genetics*; D002177:Candidiasis / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D016172:DNA Fingerprinting / Q000379:methods*; D004271:DNA, Fungal / Q000235:genetics*; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D005838:Genotype; D016519:Hospitals, Religious; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000453:epidemiology / Q000382:microbiology*; D019102:Infant, Very Low Birth Weight; D017053:Infection Control; D007363:Intensive Care Units, Neonatal; D017720:Molecular Epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012384:Rome / Q000453:epidemiology
chemical_list: D004271:DNA, Fungal