Application of the IFBC/ILSI allergenicity assessment decision tree: an industry perspective.
Three case studies are described; each represents a specific application of the IFBC/ILSI decision tree as prescribed by Metcalfe et al. to assess the allergenic potential of foods derived from genetically engineered crop plants. The case studies include high methionine soybean, high oleic soybean and Herculex TM 1 Insect Protected Maize, the results of which support/validate the use of the IFBC/ILSI decision tree for the prescribed applications.
Lamb
Ian C
IC
Regulatory Science and Registration, Pioneer Hi-Bred International, Inc., Johnston, Iowa 50131, USA. ian.lamb@pioneer.com
D000485:Allergens / Q000737:chemistry* / Q000276:immunology*; D015153:Blotting, Western; D018556:Crops, Agricultural / Q000235:genetics*; D003627:Data Interpretation, Statistical; D003663:Decision Trees; D005818:Genetic Engineering; D006801:Humans; D019301:Oleic Acid / Q000378:metabolism; D013025:Glycine max / Q000235:genetics / Q000276:immunology
D000485:Allergens; D019301:Oleic Acid