A case of hypereosinophilic syndrome presenting mid-ventricular obstruction.
A 59-year-old man with hypereosinophilic syndrome (HES) who had been maintained with low-dose prednisolone for 5 years developed the characteristic features of hypertrophic cardiomyopathy. Left ventricular endomyocardial biopsy revealed no eosinophilic infiltration but extensive myocardial fibrosis. Cardiac involvement in HES presents as endocardial fibrosis, resulting in a clinical presentation of restrictive cardiomyopathy. HES heart disease can also present dilated cardiomyopathy, but myocardial hypertrophy has only rarely been noted in conjunction with HES. This report concerns a patient with HES who had clinical and hemodynamic evidence of asymmetric septal hypertrophy with mid-ventricular obstruction.
Nakaoka
Yoshikazu
Y
Department of Molecular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Iwahori
Kota
K
Kunisada
Keita
K
Fujio
Yasushi
Y
Izumi
Masahiro
M
Osugi
Tomoaki
T
Oshima
Yuichi
Y
Hirota
Hisao
H
Yamauchi-Takihara
Keiko
K
D009202:Cardiomyopathies / Q000473:pathology*; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005355:Fibrosis; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology