[Inhibitory effect of conjugated linoleic acid on human gastric carcinoma cell line].
The effects of conjugated linoleic acid (CLA) on human gastric carcinoma cell line (SGC-7901) were studied in cell culture. The four levels of CLA in medium were designed as 25, 50, 100 and 200 mumol/L, and the dissolvent control being ethane. The result displayed that CLA could inhibit the cell proliferation, cellular mitosis, cell clone formation and DNA synthesis and induce cellular differentiation of SGC-7901 cells.
Liu
J
J
Public Health School of Harbin Medical University, Harbin 150001, China.
Chen
B
B
Liu
R
R
Lu
G
G
D000230:Adenocarcinoma / Q000473:pathology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D008041:Linoleic Acids / Q000494:pharmacology*; D013274:Stomach Neoplasms / Q000473:pathology*; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D008041:Linoleic Acids