Prevalence, species distribution and antifungal sensitivity of vaginal yeasts in infertile women.
A total of 326 high vaginal swabs from infertile women attending the Institute of Reproductive Medicine were cultured from June 1999 to May 2000. Candida species was isolated from 42(12.88%) patients. Candida albicans (40.47%) followed by Candida glabrata (38.09%) were the most common isolates. Other species included Candida tropicalis (14.28%) and Candida krusei (7.14%). All isolates were tested for sensitivity by disc diffusion method on Yeast Nitrogen Agar base towards four antifungals. Seven (16.7%) candida strains showed resistance to Fluconazole and 19(45.23%) of the strains showed resistance to Itraconazole, and 4(9.5%) strains showed resistance to Nystatin. There was no resistance to Amphotericin B. Of the 7 strains resistant to Fluconazole, 3 were Candida krusei, 3 were Candida glabrata and 1 was Candida tropicalis.
Verghese
S
S
Department of Microbiology, Institute of Reproductive Medicine, Chennai.
Padmaja
P
P
Asha
M
M
Elizabeth
S J
SJ
Anitha
A
A
Kundavi
K M
KM
Jayanthi
N
N
Varma
T
T
D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D002175:Candida / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D002181:Candidiasis, Vulvovaginal / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D025141:Drug Resistance, Fungal; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications / Q000382:microbiology*
D000935:Antifungal Agents