title: Clear cell myomelanocytic tumor of the thigh: report of a unique case.
abstract: The clear cell myomelanocytic tumor (CCMMT) is a recently reported and very rare member of the perivascular epithelioid cell family of tumors (PEComa). All CCMMTs reported to date have occurred in or immediately adjacent to the falciform ligament/ligamentum teres. We report a case of CCMMT that occurred in the right thigh of a 43-year-old woman. Histologic examination showed the classic features of CCMMT, and immunohistochemical studies confirmed co-expression of smooth muscle actin, HMB-45, and microphthalmia transcription factor.
authors.affiliation: Department of Pathology, Emory University, Atlanta, Georgia 30322, USA. afolpe@bellsouth.net
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Folpe
authors.forename: Jesse K
authors.initials: JK
authors.lastname: McKenney
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Li
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Smith
authors.forename: Sharon W
authors.initials: SW
authors.lastname: Weiss
mesh_terms: D000199:Actins / Q000378:metabolism; D000328:Adult; D018207:Angiomyolipoma / Q000473:pathology; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins / Q000378:metabolism; D003937:Diagnosis, Differential; D015622:Epithelioid Cells / Q000378:metabolism / Q000473:pathology*; D005260:Female; D005487:Foam Cells / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008544:Melanocytes / Q000378:metabolism / Q000473:pathology*; D058950:Melanoma-Specific Antigens; D051739:Microphthalmia-Associated Transcription Factor; D019042:Muscle Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D009363:Neoplasm Proteins / Q000378:metabolism; D012509:Sarcoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D014157:Transcription Factors
chemical_list: D000199:Actins; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins; C497234:MITF protein, human; D058950:Melanoma-Specific Antigens; D051739:Microphthalmia-Associated Transcription Factor; D009363:Neoplasm Proteins; D014157:Transcription Factors