Small artery remodeling and significance in the development of hypertension.
The structure of the resistance vessels is altered (remodeled) in individuals with high blood pressure (essential hypertension). The structure is dependent not only on blood pressure but also on blood flow and hormonal environment. Vascular biology is providing increased knowledge of the mechanisms involved and thus contributing to our understanding of the pathophysiology of the disease.
Mulvany
Michael J
MJ
Department of Pharmacology, University of Aarhus, 8000 Aarhus C, Denmark.
D000818:Animals; D001158:Arteries / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000473:pathology* / Q000503:physiopathology*