Flavonoids from Tephrosia aequilata.
From the roots of the plant Tephrosia aequilata Baker, five flavonoids were isolated of which, 3,4:8,9-dimethylenedioxypterocarpan is reported for the first time. Its structure and those of the already known flavonoids were established by physical and spectroscopic analysis. Application of 2D NMR techniques was useful for complete characterization of the new pterocarpan as well as the other known flavonoids.
Tarus
Paul K
PK
Chemistry Department, Kenyatta University, PO Box 43844, Nairobi, Kenya.
Machocho
Alex K
AK
Lang'at-Thoruwa
Caroline C
CC
Chhabra
Sumesh C
SC
D000818:Animals; D002460:Cell Line; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D020128:Inhibitory Concentration 50; D007630:Kenya; D007893:Leishmania donovani / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D010963:Plasmodium falciparum / Q000187:drug effects; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D031304:Tephrosia / Q000737:chemistry*; D014345:Trypanosoma / Q000187:drug effects / Q000254:growth & development
D005419:Flavonoids; D010936:Plant Extracts