title: Circling mouse, a spontaneous mutant in the inner ear.
abstract: A spontaneous mutant was established in the ICR mouse strain. The affected mice became hyperactive at about 7 days of age, and then showed circling behavior. The body weight decreased significantly 2 weeks after birth, and developmental defects were revealed in the middle ear, cochlea, cochlear nerve, and semicircular canal areas. The mutation was inherited by an autosomal single recessive gene and is referred to as cir.
authors.affiliation: Laboratory Animal Center, Catholic Research Institutes of Medical Science, Catholic Medical College, Seoul 137-701, Korea.
authors.forename: Jeong Woong
authors.initials: JW
authors.lastname: Lee
authors.forename: Zae Young
authors.initials: ZY
authors.lastname: Ryoo
authors.forename: Eun Ju
authors.initials: EJ
authors.lastname: Lee
authors.forename: Sung Hwa
authors.initials: SH
authors.lastname: Hong
authors.forename: Won Ho
authors.initials: WH
authors.lastname: Chung
authors.forename: Hoon Taek
authors.initials: HT
authors.lastname: Lee
authors.forename: Kil Saeng
authors.initials: KS
authors.lastname: Chung
authors.forename: Tae Yoon
authors.initials: TY
authors.lastname: Kim
authors.forename: Yang Seok
authors.initials: YS
authors.lastname: Oh
authors.forename: Jun Gyo
authors.initials: JG
authors.lastname: Suh
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D001835:Body Weight; D003051:Cochlea / Q000002:abnormalities; D007758:Ear, Inner / Q000002:abnormalities*; D005260:Female; D005808:Genes, Recessive; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D008817:Mice, Mutant Strains / Q000033:anatomy & histology / Q000235:genetics* / Q000502:physiology; D010375:Pedigree; D010641:Phenotype