title: Hyperbaric oxygen may reduce gas bubbles in decompressed prawns by eliminating gas nuclei.
abstract: It is accepted that gas bubbles grow from preexisting gas nuclei in tissue. The possibility of eliminating gas nuclei may be of benefit in preventing decompression sickness. In the present study, we examined the hypothesis that hyperbaric oxygen may replace the resident gas in the nuclei with oxygen and, because of its metabolic role, eliminate the nuclei themselves. After pretreatment with oxygen, prawns were 98% saturated with nitrogen before explosive decompression at 30 m/min. Ten transparent prawns were exposed to four experimental profiles in a crossover design: 1) 10-min compression to 203 kPa with air; 2) 10-min compression with oxygen; 3) 10-min compression with oxygen to 203 kPa followed by 12 min air at 203 kPa; and 4) 10 min in normobaric oxygen followed by compression to 203 kPa with air. Bubbles were measured after explosive decompression. We found that pretreatment with hyperbaric oxygen (profile C) significantly reduces the number of bubbles and bubble volume. We suggest that hyperbaric oxygen eliminates bubble nuclei in the prawn.
authors.affiliation: Israel Naval Medical Institute, Israel Defense Force Medical Corps, Haifa 31080, Israel. yehuda_a@maoz.org.il
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Arieli
authors.forename: Ran
authors.initials: R
authors.lastname: Arieli
authors.forename: Amit
authors.initials: A
authors.lastname: Marx
mesh_terms: D000818:Animals; D018592:Cross-Over Studies; D033364:Decapoda; D003664:Decompression / Q000379:methods*; D005740:Gases / Q000037:antagonists & inhibitors*; D006931:Hyperbaric Oxygenation; D008863:Microspheres; D009584:Nitrogen / Q000494:pharmacology; D010100:Oxygen / Q000494:pharmacology; D013997:Time Factors
chemical_list: D005740:Gases; D009584:Nitrogen; D010100:Oxygen