title: Advanced pairwise structure alignments of proteins and analysis of conformational changes.
abstract: BACKGROUND
  Comparing the 3D structures of two proteins or analyzing the structural changes undergone by a protein upon ligand binding or when it crystallizes under different conditions, can be both tricky and tedious, especially when the two proteins are distantly related, or when the structural changes are complex. Readily accessible tools for performing these tasks automatically and reliably should therefore be welcome.
  
  
  RESULTS
  We describe a web interface to several automatic procedures for performing pairwise structure superposition in a flexible manner, for detailed analyses of conformational changes and for displaying the results in a pictorial fashion.
  
  
  BACKGROUND
  This interface can be accessed at the Brussels and Cuba Web sites, respectively: http://www.ucmb.ulb.ac.be/SCMBB/Tools.htmland http://bio.cigb.edu.cu.
authors.affiliation: Center for Genetic Engineering and Biotechnology, Ave. 31 between Avenues 158 and 190, Cubanacán, City of Havana, 10600 Cuba.
authors.forename: Maria Elena
authors.initials: ME
authors.lastname: Ochagavia
authors.forename: Jean
authors.initials: J
authors.lastname: Richelle
authors.forename: Shoshana J
authors.initials: SJ
authors.lastname: Wodak
mesh_terms: D000465:Algorithms; D002352:Carrier Proteins / Q000737:chemistry*; D016000:Cluster Analysis; D021621:Imaging, Three-Dimensional / Q000379:methods; D020407:Internet; D008958:Models, Molecular; D010363:Pattern Recognition, Automated; D011487:Protein Conformation; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods; D014584:User-Computer Interface
chemical_list: D002352:Carrier Proteins; C037853:glutamine transport proteins