title: Serological evidence of herpesvirus infection in gibbons.
abstract: BACKGROUND
  Herpesviruses are not only infectious agents of worldwide distribution in humans, but have also been demonstrated in various non-human primates as well. Seventy-eight gibbons were subjected to serological tests by ELISA for herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), Epstein-Barr virus (EBV) and cytomegalovirus (CMV).
  
  
  RESULTS
  The prevalence of IgG antibodies against HSV-1, HSV-2, EBV and CMV was 28.2%, 28.2%, 14.1% and 17.9%, respectively.
  
  
  CONCLUSIONS
  Antigenic cross-reactivity is expected to exist between the human herpesviruses and gibbon herpesviruses. Gibbons have antibodies to human herpesviruses that may reflect zoonotic infection with human herpesviruses or infection with indigenous gibbon herpesviruses. Therefore, it is difficult to draw concrete conclusions from serological studies alone. Identification should be based on further isolation and molecular characterization of viruses from seropositive animals.
authors.affiliation: Interdepartment of Microbiology, Faculty of Graduate Studies, Chulalongkorn University, Bangkok 10330, Thailand. kamol.s@chula.ac.th
authors.forename: Kamol
authors.initials: K
authors.lastname: Sakulwira
authors.forename: Apiradee
authors.initials: A
authors.lastname: Theamboonlers
authors.forename: Phingphol
authors.initials: P
authors.lastname: Charoonrut
authors.forename: Parntep
authors.initials: P
authors.lastname: Ratanakorn
authors.forename: Yong
authors.initials: Y
authors.lastname: Poovorawan
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D003429:Cross Reactions; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000097:blood; D020031:Epstein-Barr Virus Infections / Q000097:blood; D006566:Herpesviridae Infections / Q000097:blood*; D018259:Herpesvirus 1, Human / Q000276:immunology*; D018258:Herpesvirus 2, Human / Q000276:immunology*; D004854:Herpesvirus 4, Human / Q000276:immunology; D006922:Hylobates; D012698:Serologic Tests
chemical_list: D000914:Antibodies, Viral