title: Cloning of a novel homeobox (NK-7.1) containing gene, DmHboxNK-7.1, from Drosophila melanogaster.
abstract: We have cloned a novel Drosophila melanogaster homeobox (Hbox) containing gene, NK-7.1 (Dm.HboxNK-7.1), which is located at 88B3 on the chromosome map, and is 1.5 kb downstream of the spn-B gene. The newly identified gene is expressed at high levels in the embryo, is switched off during larval and pupal stages, and is expressed again in the adult. The Hbox is highly similar to NK-1/S59 (Drosophila) and NK-3/bap (Drosophila). The amino acid (aa) identity ratios (%) were 58 between NK-7.1 and NK-1/S59, and between NK-7.1 and NK-3/bap. The other characteristic structures are the presence of homopolymeric aa stretches consisting of Q, N, and E.
authors.affiliation: Department of Genetics, Osaka University Medical School, Japan. sakoyama@genetic.med.osaka-u.ac.jp
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Sakoyama
authors.forename: Ikuko
authors.initials: I
authors.lastname: Mizuta
authors.forename: Akihiro
authors.initials: A
authors.lastname: Fukunaga
authors.forename: Masanobu
authors.initials: M
authors.lastname: Michinomae
authors.forename: Phillip R
authors.initials: PR
authors.lastname: Smith
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D018076:DNA, Complementary; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D005801:Genes, Homeobox; D017344:Genes, Insect; D018398:Homeodomain Proteins / Q000235:genetics*; D008969:Molecular Sequence Data
chemical_list: D018076:DNA, Complementary; D029721:Drosophila Proteins; D018398:Homeodomain Proteins; C466199:NK7.1 protein, Drosophila