title: Detection of recurrent nasopharyngeal carcinomas with positron emission tomography using 18-fluoro-2-deoxyglucose in patients with indeterminate magnetic resonance imaging findings after radiotherapy.
abstract: OBJECTIVE
  The aim of this study was to evaluate the effectiveness of positron emission tomography (PET) using 18-fluoro-2-deoxyglucose (FDG) to detect recurrent nasopharyngeal carcinomas (NPC) when magnetic resonance imaging (MRI) findings are indeterminate.
  
  
  METHODS
  After radiotherapy, 28 NPC patients with indeterminate MRI findings were included. MRI, FDG-PET, and biopsy were performed at least 4 months after radiotherapy and within 1 week. The final results were based on histopathologic findings and a clinical follow-up of at least 6 months.
  
  
  RESULTS
  For detecting recurrent NPC in indeterminate MRI findings, the sensitivity, specificity and accuracy of FDG-PET were 100.0%, 92.9% and 96.4%, respectively.
  
  
  CONCLUSIONS
  Based on these results, we can recommend FDG-PET for detecting recurrent NPC when MRI findings are indeterminate.
authors.affiliation: Department of Otolaryngology, China Medical College Hospital, Taichung, Taiwan.
authors.forename: M H
authors.initials: MH
authors.lastname: Tsai
authors.forename: Y C
authors.initials: YC
authors.lastname: Shiau
authors.forename: C H
authors.initials: CH
authors.lastname: Kao
authors.forename: Y Y
authors.initials: YY
authors.lastname: Shen
authors.forename: C C
authors.initials: CC
authors.lastname: Lin
authors.forename: C C
authors.initials: CC
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D011859:Radiography; D019275:Radiopharmaceuticals; D012008:Recurrence; D014055:Tomography, Emission-Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18