title: [Aminoglycoside antibiotics and post-antibiotic effects].
abstract: BACKGROUND
  Man has been fighting diseases for centuries. One of the major battles is against microorganisms and diseases they cause. A health education course was organized on prescribing aminoglycoside antibiotics and postantibiotic effect. The aim of the course was to change the prescription habits in our colleagues. The postantibiotic effect of aminoglycoside antibiotics as well as impact of subinhibiting doses on duration of postantibiotic effect requires modification of previous therapeutic protocols. Single daily dose has the same or even greater effect than multiple daily doses. The toxicity of aminoglycosides is not increased and remains the same or smaller in single daily regimens.
  
  
  RESULTS
  The single daily dose regimen of aminoglycosides has been used in 63.6% of cases in Clinic for Infectious Diseases of the Clinical Center of Novi Sad, 41.2% in Outpatient Health Care Center of Novi Sad "Liman" and this regimen has not been used in General Practice Department, Children's Health Care Department and Ear, Nose and Throat Clinic at all. The twice daily regimen has been used instead.
  
  
  CONCLUSIONS
  Doctors are aware of the postantibiotic effect, but vast majority are still bound to their old habits in regard to prescribing antibiotics. Our educational course failed to achieve its goal.
authors.affiliation: Klinika za infektivne bolesti, Klinicki centar, Novi Sad, Medicinski fakultet, Novi Sad. stefanns@eunet.yu
authors.forename: Sandra
authors.initials: S
authors.lastname: Stefan-Mikić
authors.forename: Ana
authors.initials: A
authors.lastname: Sabo
authors.forename: Milotka
authors.initials: M
authors.lastname: Fabri
authors.forename: Ana
authors.initials: A
authors.lastname: Gobor-Fodor
authors.forename: Marija
authors.initials: M
authors.lastname: Vasović
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development; D004334:Drug Administration Schedule; D004363:Drug Utilization; D006801:Humans
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents