Orthomolecular oncology: a mechanistic view of intravenous ascorbate's chemotherapeutic activity.
The effect of vitamin C in cancer has been a subject of great controversy; mainly because of the inconsistent results obtained by oral intakes of ascorbate when used as an anticancer agent. We believe the intravenous application of ascorbate will provide more consistent results in cancer patients since Vitamin C blood levels attained are substantially higher in a range proven cytotoxic to malignant cells. In this article we will present and discuss our proposed mechanism on the chemotherapeutic activity exhibited by ascorbate.
González
Michael J
MJ
University of Puerto Rico, Medical Sciences Campus, School of Public Health, Dept. Human Development, Nutrition Program, RECNAC II Project, GPO Box 365067, San Juan, PR, USA.
Miranda-Massari
Jorge R
JR
Mora
Edna M
EM
Jiménez
Ivonne Z
IZ
Matos
María Isabel
MI
Riordan
Hugh D
HD
Casciari
Joseph J
JJ
Riordan
Neil H
NH
Rodríguez
Marielys
M
Guzmán
Angelik
A
D000975:Antioxidants / Q000008:administration & dosage*; D001205:Ascorbic Acid / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D009369:Neoplasms / Q000188:drug therapy*; D009974:Orthomolecular Therapy
D000975:Antioxidants; D001205:Ascorbic Acid