title: Demodicidosis revisited.
abstract: Demodex mites are common commensals of the pilosebaceous unit in mammals. In humans, only two species (Demodex folliculorum and D. brevis) have been identified and have been implied to play a role in at least three facial conditions: pityriasis folliculorum, rosacea-like demodicidosis and so-called "demodicidosis gravis". However, there is no consensus to what degree the mites are causative of the skin pathology and how they might contribute to the disease. This review presents a demodicidosis case, discusses the clinical features of Demodex infestation in man and reviews its pathogenetic implications and the therapeutic options.
authors.affiliation: Department of Dermatology, University of Leipzig, Germany. baib@vz.uni-leipzig.de
authors.forename: B
authors.initials: B
authors.lastname: Baima
authors.forename: M
authors.initials: M
authors.lastname: Sticherling
mesh_terms: D000328:Adult; D017677:Age Distribution; D000818:Animals; D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000469:parasitology / Q000473:pathology; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage; D008924:Mite Infestations / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D008925:Mites / Q000145:classification*; D011379:Prognosis; D012307:Risk Factors; D012393:Rosacea / Q000175:diagnosis; D017678:Sex Distribution; D016896:Treatment Outcome
chemical_list: D008795:Metronidazole