title: A new case of acute idiopathic frosted branch angiitis in Europe.
abstract: METHODS
  A 20-year-old male with no history of any systemic or eye disease developed loss of visual acuity in both eyes. White exudates surrounding the retinal veins from the posterior pole to the periphery, retinal edema and hemorrhages in both eyes were evident on ophthalmoscopy. Fluorescein angiography showed leakage of the dye from the veins and extensive staining of the vein walls. A diagnosis of acute frosted branch angiitis was made. Systemic examination revealed axillary, submandibular and inguinal lymphadenopathies. VCA IgM antibody for Epstein-Barr virus was negative and IgG positive. Biopsy was taken of an axillary lymph node; a non-specific inflammatory reaction was found on anatomopathologic study. The patient was started on 90 mg prednisolone daily. After two weeks retinal vasculitis had improved and the lymphadenopathies soon resolved. Small, hard exudates were present in the posterior pole during absorption of the retinal edema and resolution of the vascular inflammation. Systemic prednisolone were reduced progressively and definitively withdrawn two months later. The patient's visual acuity was 20/25 in both eyes. No fibrotic scar tissue or atrophic lesions were noted in either fundus.
  
  
  CONCLUSIONS
  We report a new case of acute frosted branch angiitis with an onset and favorable clinical course similar to previous reports. We found the additional presence of lymphadenopathies but have been unable to establish a possible causal agent. To our knowledge, apart from a recent case of frosted branch angiitis-like response in Greece, the present case is the first reported in western Europe.
authors.affiliation: Department of Ophthalmology, University Hospital Arnau de Vilanova, Lleida, Spain. v_huerva@wanadoo.es
authors.forename: V
authors.initials: V
authors.lastname: Huerva
authors.forename: T
authors.initials: T
authors.lastname: Puig
authors.forename: M C
authors.initials: MC
authors.lastname: Sánchez
authors.forename: C
authors.initials: C
authors.lastname: Jurjo
authors.forename: J
authors.initials: J
authors.lastname: Asenjo
mesh_terms: D000208:Acute Disease; D000328:Adult; D005122:Exudates and Transudates; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000188:drug therapy; D008269:Macular Edema / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012166:Retinal Hemorrhage / Q000175:diagnosis / Q000188:drug therapy; D031300:Retinal Vasculitis / Q000175:diagnosis* / Q000188:drug therapy; D012169:Retinal Vein / Q000187:drug effects / Q000473:pathology*; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone