title: Iridoid glycosides from Globularia davisiana.
abstract: From the ethanolic extract of the aerial parts of Globularia davisiana, a new iridoid glycoside, davisioside (1), was isolated. Davisioside (1) comprises a rare iridoid aglycone structure with a saturated double bond between C-3 and C-4. Nine known iridoid glycosides, asperuloside (2), alpinoside (3), geniposide (4), globularin (5), globularicisin (6), 10-O-benzoylcatalpol (7), lytanthosalin (8), melampyroside (9), agnuside (10), and three known phenylethanoid glycosides, verbascoside, isoacteoside and leucosceptoside A were also isolated and characterized. The structures of the isolates were established by spectroscopic methods (one-dimensional (1D)- and two-dimensional (2D)-NMR, MS).
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey. icalis@hacettepe.edu.tr
authors.forename: Ihsan
authors.initials: I
authors.lastname: Caliş
authors.forename: Hasan
authors.initials: H
authors.lastname: Kirmizibekmez
authors.forename: Deniz
authors.initials: D
authors.lastname: Taşdemir
authors.forename: Chris M
authors.initials: CM
authors.lastname: Ireland
mesh_terms: D001713:Biphenyl Compounds; D002851:Chromatography, High Pressure Liquid; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D009904:Optical Rotation; D010851:Picrates; D028083:Scrophulariaceae / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared
chemical_list: D001713:Biphenyl Compounds; D039823:Iridoids; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl