Evolution of antimicrobial prophylaxis in obstetric surgery.
Problems concerning antimicrobial prophylaxis in obstetric surgery are reviewed from the first experiences with multiple-dose treatments to the new short-term prophylaxis. With the purpose to evaluate the effectiveness of a short-term scheme, a controlled population of 134 obstetric patients was treated with a double dose of 2 g i.m. of cefotetan. Clinically important infectious complications were not observed.
Orlandi
M C
MC
Istituto di Clinica Ostetrica e Ginecologica, Pisa, Italy.
Melis
G B
GB
Rossini
D
D
Macchia
A
A
Fioretti
P
P
D000328:Adult; D019072:Antibiotic Prophylaxis / Q000639:trends*; D015313:Cefotetan / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D002511:Cephalosporins / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D013513:Obstetric Surgical Procedures / Q000009:adverse effects*; D013530:Surgical Wound Infection / Q000517:prevention & control*
D002511:Cephalosporins; D015313:Cefotetan