cDNA cloning and characterization of porcine histamine H4 receptor.
The cDNA encoding histamine H4 receptor was cloned from the porcine spleen cDNA library. Porcine H4 receptor, which shares 72% homology with its human counterpart, bound to histamine in receptor-expressing mammalian cells. Isolation of the porcine H4 receptor, which is important for understanding of the pharmacology, will aid in better interpretation of physiological role of this subtype of histamine receptor.
Oda
Tamaki
T
Helix Research Institute, Inc., 1532-3 Yana, Kisarazu, Chiba, 292-0812, Japan.
Matsumoto
Shun-ichiro
S
Masuho
Yasuhiko
Y
Takasaki
Jun
J
Matsumoto
Mitsuyuki
M
Kamohara
Masazumi
M
Saito
Tetsu
T
Ohishi
Takahide
T
Soga
Takatoshi
T
Hiyama
Hideki
H
Matsushime
Hitoshi
H
Furuichi
Kiyoshi
K
D000595:Amino Acid Sequence; D000818:Animals; D016466:CHO Cells; D003001:Cloning, Molecular; D006224:Cricetinae; D018076:DNA, Complementary / Q000235:genetics; D008969:Molecular Sequence Data; D009928:Organ Specificity; D043562:Receptors, G-Protein-Coupled; D011968:Receptors, Histamine / Q000235:genetics* / Q000378:metabolism; D016415:Sequence Alignment; D013552:Swine
D018076:DNA, Complementary; D043562:Receptors, G-Protein-Coupled; D011968:Receptors, Histamine