Diagnosis of epizootic bovine abortion in Nevada and identification of the vector.
In the 43 years since the first description in California, epizootic bovine abortion (EBA) has been considered but not definitively diagnosed as a cause of late-term abortions on Nevada ranches. Examination of aborted full-term bovine fetuses obtained from Nevada ranches revealed gross abnormalities consistent with EBA (enlarged lymph nodes, petechial hemorrhages of the oral mucosa and conjunctiva, ascites, and splenohepatomegaly), and EBA was confirmed by histologic examination of fetal tissues. The histologic thymic changes were characteristic of EBA and included severe histocytic thymusitis with depletion of thymocytes, interlobular hemorrhage, and fibrinocellular exudation. The gross enlargement of lymph nodes was the result of cortical follicular hyperplasia and histiocytic lymphadenitis. In addition, widespread, predominately nonsuppurative histologic lesions typical of EBA were observed in most organs, including the brain, lung, heart, liver, and spleen. Furthermore, the presence of Ornithodorus coriaceus, the argasid tick vector of EBA, was established by tick collection using CO2 traps. The tick was identified on ranches and in geographic areas (northern and northwestern counties of Nevada) coincident with diagnosis of multiple cases of EBA. This study establishes the presence of EBA as a cause of late-term abortion in Nevada. Additionally, identification of the EBA tick vector, O. coriaceus, in the same areas as the abortions provides strong evidence that the disease is endemic.
Hall
Mark R
MR
Department of Animal Biotechnology, College of Agriculture, Biotechnology and Natural Resources, University of Nevada, Reno 89557, USA.
Hanks
Donald
D
Kvasnicka
William
W
Bosomworth
Alan
A
Smith
Harry
H
Stott
Jeffrey L
JL
Blanchard
Myra T
MT
Anderson
Mark L
ML
D000034:Abortion, Veterinary / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission; D000818:Animals; D001179:Arthropod Vectors; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D008208:Lymphatic System / Q000473:pathology; D009505:Nevada / Q000453:epidemiology; D026861:Ornithodoros / Q000472:pathogenicity*; D011247:Pregnancy; D013984:Tick Infestations / Q000662:veterinary*