Type 2 diabetes mellitus in childhood--a global perspective.
Type 2 diabetes mellitus is a group of diseases of different etiologies but similar symptopathology characterized by insulin resistance (insulin insensitivity) of different degrees. It can be associated with specific genetic mutations, with a series of chromosomal abnormalities, with states of lean body or obesity, the latter showing a worrying increase in incidence. The literature on the above is reviewed and a personal opinion is expressed on the prevention and treatment of the above conditions.
Laron
Zvi
Z
Endocrinology and Diabetes Research Unit, Schneider Children's Medical Center, WHO Collaborating Center for the Study of Diabetes in Youth, Tel Aviv University, Israel. laronz@clalit.org.il
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003920:Diabetes Mellitus; D003922:Diabetes Mellitus, Type 1; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D005215:Fasting; D005951:Glucose Tolerance Test; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000097:blood; D009765:Obesity; D012307:Risk Factors
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin