title: [Characterization of Vibrio cholerae eltor in the city of Kazan in 2001].
abstract: Information on V. cholerae eltor isolated in the focus of cholera in Kazan in 2001 at different periods of the outbreak is presented. The identity of strains isolated from patients, vibriocarriers and environmental objects, including their antibioticograms (sensitivity to cyprofloxacin and resistance to trimethoprim--sulfamethoxazole, streptomycin, furazolidone and nalidixic acid, which may be regarded as markers), is shown. Variable tandem repetitions in the DNA of 30 isolates strains of different origin have been determined. The results of this determination make it possible to classify all these strains as one genotype, which confirms the suggestion on the circulation of one subclone of the infective agent of cholera in the focus. As revealed in this investigation, the isolated strains are labile with respect to diagnostic phage eltor, while ctx+ strains are resistant to phage eltor ctx+.
authors.affiliation: Ministry of Health, Russian Federation, Moscow.
authors.forename: G G
authors.initials: GG
authors.lastname: Onishchenko
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Lomov
authors.forename: B N
authors.initials: BN
authors.lastname: Mishan'kin
authors.forename: B L
authors.initials: BL
authors.lastname: Mazrukho
authors.forename: L S
authors.initials: LS
authors.lastname: Podosinnikova
authors.forename: T A
authors.initials: TA
authors.lastname: Kudriakova
authors.forename: E A
authors.initials: EA
authors.lastname: Moskvitina
authors.forename: S O
authors.initials: SO
authors.lastname: Vodop'ianov
authors.forename: I V
authors.initials: IV
authors.lastname: Ryzhko
authors.forename: E S
authors.initials: ES
authors.lastname: Kazakova
authors.forename: I N
authors.initials: IN
authors.lastname: Sharova
authors.forename: E A
authors.initials: EA
authors.lastname: Plotnikova
authors.forename: N A
authors.initials: NA
authors.lastname: Davydova
authors.forename: E G
authors.initials: EG
authors.lastname: Abramova
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Korolev
authors.forename: I S
authors.initials: IS
authors.lastname: Shestialtynova
authors.forename: D M
authors.initials: DM
authors.lastname: Sharifulina
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Kuriaeva
authors.forename: E F
authors.initials: EF
authors.lastname: Iumangulova
authors.forename: A V
authors.initials: AV
authors.lastname: Chernyshova
authors.forename: T V
authors.initials: TV
authors.lastname: Bugorkova
authors.forename: T G
authors.initials: TG
authors.lastname: Rusakova
authors.forename: A L
authors.initials: AL
authors.lastname: Maslenikova
authors.forename: M V
authors.initials: MV
authors.lastname: Milova
authors.forename: L I
authors.initials: LI
authors.lastname: Zakharova
authors.forename: T G
authors.initials: TG
authors.lastname: Bilalova
authors.forename: A G
authors.initials: AG
authors.lastname: Shut'ko
authors.forename: G V
authors.initials: GV
authors.lastname: Kachkina
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000627:therapeutic use; D015415:Biomarkers; D002771:Cholera / Q000188:drug therapy / Q000453:epidemiology / Q000378:metabolism*; D002939:Ciprofloxacin / Q000627:therapeutic use; D004352:Drug Resistance, Microbial / Q000235:genetics; D005664:Furazolidone / Q000378:metabolism; D005838:Genotype; D006801:Humans; D009268:Nalidixic Acid / Q000378:metabolism; D012426:Russia / Q000453:epidemiology; D013307:Streptomycin / Q000378:metabolism; D013420:Sulfamethoxazole / Q000378:metabolism; D014296:Trimethoprim Resistance / Q000235:genetics; D014734:Vibrio cholerae / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D015415:Biomarkers; D009268:Nalidixic Acid; D002939:Ciprofloxacin; D005664:Furazolidone; D013420:Sulfamethoxazole; D013307:Streptomycin