Specificity of gene regulation.
The physiologically coordinated expression of our genome requires exquisite regulation of gene specificity. Recent advances demonstrate that this formidable task is accomplished by diverse mechanisms and networks that operate at distinct levels within the nucleus.
Emerson
Beverly M
BM
Salk Institute, Regulatory Biology Laboratory, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. emerson@salk.edu
D000818:Animals; D002467:Cell Nucleus / Q000502:physiology; D002843:Chromatin / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology*; D006801:Humans; D008957:Models, Genetic; D009687:Nuclear Proteins / Q000378:metabolism; D009707:Nucleosomes / Q000378:metabolism; D010448:Peptide Initiation Factors / Q000378:metabolism; D011401:Promoter Regions, Genetic; D011487:Protein Conformation; D012319:RNA Polymerase II / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic / Q000502:physiology
D002843:Chromatin; D009687:Nuclear Proteins; D009707:Nucleosomes; D010448:Peptide Initiation Factors; D014157:Transcription Factors; D012319:RNA Polymerase II