title: Two-dimensional and M-mode echocardiographic predictors of disease severity in dogs with congenital subaortic stenosis.
abstract: Echocardiographic studies from 50 dogs with congenital subaortic stenosis were examined. The degree of concentric, left-ventricular hypertrophy as assessed by M-mode measurement demonstrated a positive relationship (P<0.05) to disease severity. However, the clinical utility of these measures is hindered by a large amount of individual variation (r2=0.243 to 0.473). Two-dimensional ultrasound was used to compare the cross-sectional area of the left-ventricular outflow tract to the cross-sectional area of the aortic root. The ratio of these two areas demonstrated a strong inverse relationship (P=0.001; r2=0.778) with disease severity. This ratio provides a method of estimating severity of disease by two-dimensional echocardiography.
authors.affiliation: Department of Medicine and Epidemiology, College of Veterinary Medicine, University of California, Davis 95616, USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Oyama
authors.forename: William P
authors.initials: WP
authors.lastname: Thomas
mesh_terms: D000818:Animals; D001947:Breeding; D016022:Case-Control Studies; D021922:Discrete Subaortic Stenosis / Q000000981:diagnostic imaging / Q000662:veterinary*; D004283:Dog Diseases / Q000151:congenital / Q000000981:diagnostic imaging* / Q000473:pathology; D004285:Dogs; D004452:Echocardiography / Q000592:standards / Q000662:veterinary*; D005260:Female; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000662:veterinary*; D008297:Male; D011237:Predictive Value of Tests; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging / Q000662:veterinary