Simultaneous development of pheochromocytomas in prepubertal siblings with von Hippel-Lindau syndrome.
We report 2 siblings with a known von Hippel-Lindau mutation who simultaneously developed asymptomatic pheochromocytomas at significantly younger ages than are typically seen in this setting.
Franklin
Sherry Lynn
SL
Division of Endocrinology, Department of Pediatrics, Mattel Children's Hospital at UCLA, Los Angeles, California 90095, USA.
Eisenhofer
Graeme
G
Geffner
Mitchell E
ME
D017668:Age of Onset; D002648:Child; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D009679:Nuclear Family; D010673:Pheochromocytoma / Q000209:etiology / Q000235:genetics* / Q000601:surgery; D006623:von Hippel-Lindau Disease / Q000150:complications / Q000235:genetics* / Q000378:metabolism