title: Virucidal efficacy of four new disinfectants.
abstract: Virucidal efficacy was evaluated for four recently available disinfectants: chlorine dioxide, potassium peroxymonosulfate, a quaternary ammonium compound, and citricidal (grapefruit extract). Sodium hypochlorite (3%) and tap water were used as positive and negative controls respectively. Feline herpesvirus, feline calicivirus, and feline parvovirus were exposed to the manufacturers' recommended dilutions of the evaluated disinfectants. Both chlorine dioxide and potassium peroxymonosulfate completely inactivated the three viruses used in this study. These disinfectants can aid in controlling nosocomial transmission of viruses with less of the deleterious effects of sodium hypochlorite. The quaternary ammonium compound evaluated in this study and citricidal were not effective against feline calicivirus and feline parvovirus.
authors.affiliation: Department of Comparative Medicine, College of Veterinary Medicine, University of Tennessee, Knoxville 37901-1071, USA.
authors.forename: Nasser Z
authors.initials: NZ
authors.lastname: Eleraky
authors.forename: Leon N D
authors.initials: LN
authors.lastname: Potgieter
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Kennedy
mesh_terms: D000818:Animals; D017927:Calicivirus, Feline / Q000187:drug effects; D002371:Cat Diseases / Q000517:prevention & control; D002415:Cats; D017606:Chlorine Compounds / Q000494:pharmacology; D002957:Citrus; D003428:Cross Infection / Q000517:prevention & control / Q000662:veterinary; D004202:Disinfectants / Q000494:pharmacology*; D028301:Feline Panleukopenia Virus / Q000187:drug effects; D006564:Herpesviridae / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010087:Oxides / Q000494:pharmacology; D010545:Peroxides / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D014777:Virus Diseases / Q000517:prevention & control / Q000662:veterinary; D014780:Viruses / Q000187:drug effects*
chemical_list: D017606:Chlorine Compounds; D004202:Disinfectants; D010087:Oxides; D010545:Peroxides; D010936:Plant Extracts; D000644:Quaternary Ammonium Compounds; C038288:peroxymonosulfate; C025109:chlorine dioxide