title: [Oral antidiabetics and lipids].
abstract: Lipid abnormalities are a key factor in the vascular risk of type 2 diabetes. In this review, we briefly consider lipid abnormalities associated with type 2 diabetes. The effects of the main oral antidiabetic agents (sulphonylureas and glinides analogues, metformin, inhibitors of alpha-glucosidase) on lipoproteins are described. Thiazolidinedione (pioglitazone and rosiglitazone) effects on lipid metabolism, as well as their effects on mechanisms involved in the promotion of atherosclerosis are discussed.
authors.affiliation: Service d'Endocrinologie, Diabétologie et Maladies Métaboliques, Hôpital du Bocage, F - 21034 Dijon Cedex.
authors.forename: B
authors.initials: B
authors.lastname: Verges
mesh_terms: D000284:Administration, Oral; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D050356:Lipid Metabolism
chemical_list: D007004:Hypoglycemic Agents