Amniotic membrane graft for late-onset glaucoma filtering leaks.
OBJECTIVE
To evaluate the effectiveness and safety of amniotic membrane graft in the management of late-onset filtering bleb leaks after trabeculectomy with mitomycin C.


METHODS
Prospective, noncomparative, interventional case reports.


METHODS
Two eyes of two patients with late-onset filtering bleb leak received an amniotic membrane graft.


RESULTS
In both patients, bleb leaks were closed successfully with amniotic membrane graft, and bleb function was maintained during the follow-up period of 34 and 14 months, respectively.


CONCLUSIONS
Amniotic membrane graft may be considered an alternative method for treating late-onset filtering bleb leaks while maintaining bleb function. As the number of cases was small, more cases need to be accumulated to verify the usefulness of this technique.
Kee
Changwon
C
Department of Ophthalmology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea. cwkee@ophthalmology.org
Hwang
Jeong-Min
JM
D000328:Adult; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use; D011183:Postoperative Complications / Q000601:surgery*; D011446:Prospective Studies; D014130:Trabeculectomy / Q000009:adverse effects*; D016896:Treatment Outcome; D014792:Visual Acuity
D016685:Mitomycin