title: Vancomycin susceptibility of oxacillin-resistant Staphylococcus aureus isolates causing nosocomial bloodstream infections.
abstract: Nosocomial oxacillin-resistant Staphylococcus aureus (ORSA) bloodstream isolates were tested to determine the prevalence of vancomycin heteroresistance. We screened 619 ORSA nosocomial bloodstream isolates from 36 hospitals between 1997 and 2000. Only one isolate exhibiting heterotypic resistance was detected. Thus, vancomycin heteroresistance in clinical bloodstream isolates remains rare in the United States.
authors.affiliation: Department of Internal Medicine, Medical College of Virginia Campus of Virginia Commonwealth University, Richmond, Virginia 23298, USA. smtallen@hsc.vcu.edu
authors.forename: Sandra M
authors.initials: SM
authors.lastname: Tallent
authors.forename: Tammy
authors.initials: T
authors.lastname: Bischoff
authors.forename: Michael
authors.initials: M
authors.lastname: Climo
authors.forename: Belinda
authors.initials: B
authors.lastname: Ostrowsky
authors.forename: Richard P
authors.initials: RP
authors.lastname: Wenzel
authors.forename: Michael B
authors.initials: MB
authors.lastname: Edmond
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D006760:Hospitalization; D006801:Humans; D008826:Microbial Sensitivity Tests; D010068:Oxacillin / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology; D011159:Population Surveillance; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*; D014481:United States / Q000453:epidemiology; D014640:Vancomycin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D014640:Vancomycin; D010068:Oxacillin