[Biocompatibility studies on bioactive glass ceramics and polylactic acid combined with cultured bone marrow stromal cells in vitro].
OBJECTIVE
To study the biocompatibility on bioactive glass ceramics (BGC) and polylactic acid (PLA) combined with cultured bone marrow stromal cells (BMSCs) in bone tissue engineering.


METHODS
BMSCs were cultured combined with BGC and PLA in vitro, and the morphological characters, cell proliferation, protein content, and alkaline phosphatase activity were detected.


RESULTS
BMSCs could be attached to and extended on both BGC and PLA, and normally grown, proliferated, had active function. BGC could promote cell proliferation.


CONCLUSIONS
The results show that both BGC and PLA have good biocompatibility with BMSCs, they can be used as biomaterials for cell transplantation in tissue engineering.
Jin
D
D
Department of Orthopedic and Trauma Surgery, Nanfang Hospital, the First Military Medical University, Guangzhou Guangdong, P. R. China 510515.
Pei
G X
GX
Wang
Q
Q
D000818:Animals; D001672:Biocompatible Materials; D001854:Bone Marrow Cells / Q000166:cytology*; D002478:Cells, Cultured; D002516:Ceramics; D019344:Lactic Acid; D011091:Polyesters; D011108:Polymers; D011817:Rabbits; D017154:Stromal Cells / Q000166:cytology; D023822:Tissue Engineering
D001672:Biocompatible Materials; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide); C023506:Glass ceramics