Molecular diagnosis of viral hepatitis.
Molecular biology-based assays are invaluable tools for the management of chronic viral hepatitis. They can be used to test blood donations, diagnose active infection, help to establish the prognosis, guide treatment decisions, and assess the virological response to therapy. This article reviews current molecular biology-based techniques and assays, and their practical use in the management of hepatitis B and C virus infection.
Pawlotsky
Jean-Michel
JM
Department of Virology (EA 3489), Henri Mondor Hospital, University of Paris XII, 51 avenue du Maréchal de Lattre de Tassigny, 94010 Créteil, France. jean-michel.pawlotsky@hmn.ap-hop-paris.fr
D004279:DNA, Viral / Q000032:analysis; D016679:Genome, Viral; D016174:Hepacivirus / Q000235:genetics; D006509:Hepatitis B / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D006515:Hepatitis B virus / Q000235:genetics; D006526:Hepatitis C / Q000175:diagnosis* / Q000628:therapy / Q000821:virology; D006801:Humans; D008967:Molecular Biology / Q000379:methods*; D012367:RNA, Viral / Q000032:analysis
D004279:DNA, Viral; D012367:RNA, Viral