[Severe thyroid ophthalmopathy related to interferon alpha therapy].
The authors report a case of a 49-year-old patient presenting with dysthyroid ophthalmopathy, who was treated with interferon alpha for chronic hepatitis C. Proptosis appeared 3 months after treatment onset and many complications occurred over more than 1 year. The extreme severity seen in this case is infrequent. After a summary of other ocular damage linked to interferon, the authors suggest that every interferon treatment include a check-up before beginning therapy and regular biological and ophthalmological monitoring.
Binaghi
M
M
Service d'Ophtalmologie, Hospital Henri Mondor, Cedex, France.
Lévy
C
C
Douvin
C
C
Guittard
M
M
Soubrane
G
G
Coscas
G
G
D005260:Female; D006111:Graves Disease / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008875:Middle Aged; D016896:Treatment Outcome
D016898:Interferon-alpha