[Usefulness of low-dose irinotecan for multiple lung metastases of cholangiocellular carcinoma after operation--a case report].
We treated a patient in whom low-dose irinotecan therapy was effective for the treatment of multiple lung metastases of cholangiocellular carcinoma after operation. The patient was a 50-year-old man. He underwent extended right hepatectomy for cholangiocellular carcinoma, and multiple lung metastases occurred 8 months after operation. For the treatment of lung metastases, low-dose irinotecan therapy (70 or 40 mg/week) was carried out. Eighteen months after the lung recurrence, he is still alive with a good quality of life, although the lung metastases have progressed. These results suggest that low-dose irinotecan therapy can be effective for lung metastases of cholangiocellular carcinoma.
Kutomi
Goro
G
First Dept. of Surgery, Sapporo Medical University.
Katsuramaki
Tadashi
T
Mukaiya
Mitsuhiro
M
Hirata
Koichi
K
Shimodan
Mitsuhiro
M
Adachi
Hideaki
H
D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D001650:Bile Duct Neoplasms / Q000473:pathology / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic; D002166:Camptothecin / Q000008:administration & dosage* / Q000031:analogs & derivatives; D018281:Cholangiocarcinoma / Q000188:drug therapy* / Q000556:secondary*; D004334:Drug Administration Schedule; D006498:Hepatectomy; D006801:Humans; D000077146:Irinotecan; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged
D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D002166:Camptothecin