title: Direct electrochemistry of cytochrome c at a glassy carbon electrode modified with single-wall carbon nanotubes.
abstract: The electrochemistry of horse heart cytochrome c was studied by cyclic voltammetry at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). A pair of well-defined redox waves was obtained in cytochrome c aqueous solution at an activated SWNT film-modified electrode. The optimal conditions for activating the SWNT film-modified electrode has been determined. The electrode reaction of cytochrome c is a diffusion-controlled process. The peak current increases linearly with the concentration of cytochrome c in the range from 3.0 x 10(-5)-7.0 x 10(-4) M. The detection limit is 1.0 x 10(-5) M. The activated SWNT film was characterized by scanning electron microscopy. Furthermore, interaction of cytochrome c with adenine was characterized by electrochemical and spectral methods.
authors.affiliation: College of Chemistry and Molecular Engineering, Peking University, Beijing, People's Republic of China.
authors.forename: Jianxiu
authors.initials: J
authors.lastname: Wang
authors.forename: Meixian
authors.initials: M
authors.lastname: Li
authors.forename: Zujin
authors.initials: Z
authors.lastname: Shi
authors.forename: Nanqiang
authors.initials: N
authors.lastname: Li
authors.forename: Zhennan
authors.initials: Z
authors.lastname: Gu
mesh_terms: D000225:Adenine / Q000378:metabolism; D000818:Animals; D003574:Cytochrome c Group / Q000032:analysis / Q000737:chemistry* / Q000378:metabolism; D004563:Electrochemistry; D004566:Electrodes; D006736:Horses; D006863:Hydrogen-Ion Concentration; D036103:Nanotechnology / Q000295:instrumentation; D010084:Oxidation-Reduction; D011485:Protein Binding; D012680:Sensitivity and Specificity; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D003574:Cytochrome c Group; D000225:Adenine