title: [Neuroendocrine dysfunction in female patients with systemic dysplasia of the connective tissue].
abstract: The study covered 119 women with systemic undifferentiated dysplasia of the connective tissue (DCT) aged 14-39 years. All the examinees had vegetative disorders, 26.1% had a neuroendocrine-metabolic form of hypothalamic syndrome (HS), 51.3%--premenopausal syndrome, 65.5%--dysmenorrhea. It was found that women with DCT and HS develop symptoms of neuroendocrine disorders at earlier age than those with HS but free of DCT. Arterial hypertension was registered in 96.8% of patients with DCT and HS, 80.3% of DCT patients with premenopausal syndrome. Central hemodynamics was different in DCT patients without neuroendocrine disorders and with neuroendocrine dysfunction evidencing the role of the latter in development of arterial hypertension in DCT.
authors.forename: M A
authors.initials: MA
authors.lastname: Perekal'skaia
authors.forename: L I
authors.initials: LI
authors.lastname: Makarova
authors.forename: G N
authors.initials: GN
authors.lastname: Vereshchagina
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006964:Hyperpituitarism / Q000150:complications* / Q000503:physiopathology*; D006973:Hypertension / Q000150:complications*; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D008945:Mitral Valve Prolapse / Q000150:complications*; D009372:Neoplasms, Connective Tissue / Q000150:complications* / Q000503:physiopathology*; D010913:Pituitary-Adrenal System / Q000503:physiopathology*