title: Contribution of vitamin C administration for increasing lipolysis.
abstract: This experiment was designed to investigate whether addition of vitamin C to the solution used in tumescent technique of liposuction might increase lipolysis and whether increased fibrosis might improve skin retraction where liposuction did not work properly and the skin had poor retraction ability. Eighteen Sprague-Dawley rats were used in two groups. Both inguinal fat pads of rats with their vascular structures were elevated and the right inguinal fat pad was injected with 1 cc tumescent solution as a control and the left fat pad with a 1 cc vitamin C-tumescent solution. Histopathological examination showed that all fat pads injected with tumescent solution had normal adipocytes. Those injected with vitamin C-tumescent were shown to have extreme fibrosis and occasional adipocytes.
authors.affiliation: adanalig@yahoo.com
authors.forename: Dilek
authors.initials: D
authors.lastname: Senen
authors.forename: Gokhan
authors.initials: G
authors.lastname: Adanali
authors.forename: Meltem
authors.initials: M
authors.lastname: Ayhan
authors.forename: Metin
authors.initials: M
authors.lastname: Görgü
authors.forename: Bülent
authors.initials: B
authors.lastname: Erdogan
mesh_terms: D000273:Adipose Tissue / Q000166:cytology / Q000187:drug effects*; D000772:Anesthesia, Local; D000779:Anesthetics, Local; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage*; D004837:Epinephrine; D005355:Fibrosis; D008012:Lidocaine; D015187:Lipectomy / Q000379:methods*; D008066:Lipolysis; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000187:drug effects / Q000473:pathology
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D001205:Ascorbic Acid; D004837:Epinephrine