title: Increased frequency of HCV but not HBV infection in type 2 diabetic patients in Turkey.
abstract: The aim of this study was to investigate the prevalence of hepatitis B and hepatitis C virus infections in type 2 diabetic patients in Gaziantep, Turkey. Six hundred and ninety-two type 2 diabetic patients and 1014 healthy blood donors were included in the study. No significant difference was found between type 2 diabetic patients and the control group for seropositivity of HBsAg (5.3% vs 5.1%, p>0.05). In contrast, anti-HCV was significantly more frequent in type 2 diabetic patients (7.5% vs 0.1%, p>0.0001). We found no significant difference for HBsAg seropositivity between type 2 diabetic patients with a disease duration of 12 months or less, but anti-HCV seropositivity was significantly more frequent in diabetic patients with a longer disease duration (p<0.05). We suggest that HCV infection is not a trigger factor for type 2 diabetes mellitus but is frequently associated with it.
authors.affiliation: Department of Internal Medicine, University of Gaziantep, School of Medicine, Turkey.
authors.forename: V
authors.initials: V
authors.lastname: Okan
authors.forename: M
authors.initials: M
authors.lastname: Araz
authors.forename: S
authors.initials: S
authors.lastname: Aktaran
authors.forename: T
authors.initials: T
authors.lastname: Karsligil
authors.forename: I
authors.initials: I
authors.lastname: Meram
authors.forename: Z
authors.initials: Z
authors.lastname: Bayraktaroglu
authors.forename: F
authors.initials: F
authors.lastname: Demirci
mesh_terms: D000328:Adult; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000201:enzymology; D005260:Female; D006514:Hepatitis B Surface Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000453:epidemiology; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013997:Time Factors; D000637:Transaminases / Q000097:blood; D014421:Turkey / Q000453:epidemiology
chemical_list: D006514:Hepatitis B Surface Antigens; D000637:Transaminases