title: [Endoscopic resection of malignant melanomas of the uvea after preoperative stereotactic single dose convergence irradiation with the Leksell gamma knife].
abstract: In cases of large volume and highly prominent melanomas of the uvea, it is rare for conventional methods of radiation therapy to enable salvage of the globe or even residual functionality of the affected eye. Complications due to the massive amount of accumulated necrotic tissue often necessitate subsequent enucleation of the blinded eye. Tumor-destroying, single-dose convergence irradiation (radiosurgery) of such tumors applied shortly before endoresection can represent a possible therapeutic alternative in these types of cases.
authors.affiliation: Universitätsklinikum Essen, Zentrum für Augenheilkunde, Abteilung für Erkrankungen des hinteren Augenabschnitts, Hufelandstrasse 55, 45122 Essen. bornfeld@uni-essen.de
authors.forename: N
authors.initials: N
authors.lastname: Bornfeld
authors.forename: S
authors.initials: S
authors.lastname: Talies
authors.forename: G
authors.initials: G
authors.lastname: Anastassiou
authors.forename: H
authors.initials: H
authors.lastname: Schilling
authors.forename: A
authors.initials: A
authors.lastname: Schüler
authors.forename: G A
authors.initials: GA
authors.lastname: Horstmann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009887:Ophthalmoscopy; D011183:Postoperative Complications / Q000175:diagnosis; D016634:Radiosurgery; D018714:Radiotherapy, Adjuvant; D014604:Uveal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*