title: Challenges at the frontiers of structural biology.
abstract: A recent meeting brought together electron microscopists, crystallographers and modellers to consider the problems facing structural biologists who wish to understand large, subcellular machines, and how the methods should be extended to achieve this goal.
authors.affiliation: Helen R. Saibil is in the Department of Crystallography, Birkbeck College London, Malet Street, London, WC1E 7HX, United Kingdom. h.saibil@mail.cryst.bbk.ac.uk
authors.forename: Helen R
authors.initials: HR
authors.lastname: Saibil
authors.forename: Elena V
authors.initials: EV
authors.lastname: Orlova
mesh_terms: D000818:Animals; D020285:Cryoelectron Microscopy / Q000379:methods; D018360:Crystallography, X-Ray / Q000379:methods; D046911:Macromolecular Substances; D008968:Molecular Conformation; D017356:Synchrotrons
chemical_list: D046911:Macromolecular Substances