[How cells protect themselves against stress?].
The current evidence on the mechanisms underlying cell response to heat shock is reviewed. The response dynamics, induction, and attenuation as well as heat shock proteins and the mechanisms through which they protect cells from stress are considered. The role of these proteins in regulating the signaling cascades, including apoptosis suppression, is shown.
Khlebodarova
T M
TM
Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, 630090 Russia. tamara@bionet.nsc.ru
D000818:Animals; D005786:Gene Expression Regulation; D006360:Heat-Shock Proteins / Q000235:genetics* / Q000378:metabolism*; D018869:Heat-Shock Response / Q000502:physiology*
D006360:Heat-Shock Proteins