CNS access of selected H3-antagonists: ex vivo binding study in rats.
Ballabeni
V
V
Instituto di Farmacologia e Farmacognosia, Facoltà di Farmacia, Università di Parma, Italy.
Impicciatore
M
M
Bertoni
S
S
Magnanini
F
F
Zuliani
V
V
Vacondio
F
F
Barocelli
E
E
D000818:Animals; D002490:Central Nervous System / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006168:Guinea Pigs; D006633:Histamine Antagonists / Q000008:administration & dosage / Q000494:pharmacology*; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D066298:In Vitro Techniques; D007276:Injections, Intraventricular; D010424:Pentobarbital / Q000494:pharmacology; D051381:Rats; D011969:Receptors, Histamine H1 / Q000187:drug effects / Q000378:metabolism; D011970:Receptors, Histamine H2 / Q000187:drug effects / Q000378:metabolism; D018100:Receptors, Histamine H3 / Q000187:drug effects*; D012890:Sleep / Q000187:drug effects; D013329:Structure-Activity Relationship; D013997:Time Factors
D006633:Histamine Antagonists; D006993:Hypnotics and Sedatives; D011969:Receptors, Histamine H1; D011970:Receptors, Histamine H2; D018100:Receptors, Histamine H3; D010424:Pentobarbital