title: Cholestatic fibrosing hepatitis and hepatitis B after bone marrow transplantation.
abstract: In the setting of transplantation and chronic hepatitis B viral infection there is a unique histological feature termed cholestatic fibrosing hepatitis. The use of nucleoside analogues in the treatment of this condition has been successful. We describe a case of cholestatic fibrosing hepatitis, which occurred after intense immunosuppression for graft versus host disease in a patient with bone marrow transplantations. She was commenced on lamivudine therapy and showed good clinical, biochemical and virological response. However she succumbed due to sepsis.
authors.affiliation: Department of Medicine, Hospital Kuala Lumpur.
authors.forename: R L
authors.initials: RL
authors.lastname: Suresh
authors.forename: I
authors.initials: I
authors.lastname: Merican
authors.forename: K M
authors.initials: KM
authors.lastname: Chang
authors.forename: S M
authors.initials: SM
authors.lastname: Yong
authors.forename: V
authors.initials: V
authors.lastname: Purusothaman
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002779:Cholestasis / Q000209:etiology*; D005260:Female; D006505:Hepatitis / Q000209:etiology*; D006509:Hepatitis B / Q000209:etiology*; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology*