[A new practical route to stereospecific synthesis of (S)-(-)-ofloxacin].
(S)-(-)-ofloxacin is one of the best fluoroquinolone agents in current clinical use. A new facile practical route with good yield and high optical purity to stereospecific synthesis of (S)-(-)-ofloxacin was described.
Yang
Y
Y
Shanghai Institute of Materia Medica, Shanghai 200031.
Ji
R
R
Hu
Z
Z
Chen
K
K
D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D015242:Ofloxacin / Q000138:chemical synthesis*; D013237:Stereoisomerism
D000890:Anti-Infective Agents; D015242:Ofloxacin