[Use of cytoflavin for correction of complications of myocardial infarction].
The possibility of using a combined preparation cytoflavine was studied on rats with myocardial infarction induced by coronary artery occlusion. The drug produces a positive action upon the energy exchange and the lipid peroxidation process and normalizes functioning of the system of antioxidant protection of the ischemized myocardium. Cytoflavine treatment led to a more favorable course of ischemic and necrotic processes and optimum organization of the necrosis zones.
Bul'on
V V
VV
Department of Neuropharmacology, Institute of Experimental Medicine, Russian Academy of Medical Sciences, ul. akademika Pavlova 12, St. Petersburg, 197376 Russia.
Khnychenko
L K
LK
Sapronov
N S
NS
Kovalenko
A L
AL
Alekseeva
L E
LE
D000818:Animals; D004338:Drug Combinations; D004734:Energy Metabolism; D005260:Female; D005486:Flavin Mononucleotide / Q000627:therapeutic use*; D007290:Inosine Diphosphate / Q000627:therapeutic use*; D015227:Lipid Peroxidation; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D009536:Niacinamide / Q000627:therapeutic use*; D051381:Rats; D019802:Succinic Acid / Q000627:therapeutic use*
D004338:Drug Combinations; D009536:Niacinamide; D005486:Flavin Mononucleotide; D007290:Inosine Diphosphate; D019802:Succinic Acid