[Comparison of the results of functional tests used in non-invasive examination of endothelial function].
OBJECTIVE
To analyze results of two tests used in non-invasive assessment of endothelial function: D. Celermajer test (T1) and reactive hyperemia test (T2).


METHODS
Ultrasound investigation (7.5 MHz) was employed to measure brachial artery (BA) diameter, blood flow rate and its volume at rest above the site of occlusion (T1) and under it (T2). Control group consisted of 30 men with risk factors for atherosclerosis.


RESULTS
Peak value of the diameter dilation was within 10% in both tests, the difference being insignificant. The same dilatation of BA can be explained by different shift effect on the endothelium: in T1 the shift disturbance was longer while in T2 it was more intensive.


CONCLUSIONS
To reveal endothelial dysfunction, the site of occlusion and location of the artery are not very important. However, because the shift disturbance time is different it is desirable to use the same test modification in one trial protocol.
Martsinkevich
G I
GI
Kovalenko
I A
IA
Sokolov
A A
AA
Kim
V N
VN
D000328:Adult; D001161:Arteriosclerosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D001783:Blood Flow Velocity; D016022:Case-Control Studies; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D006940:Hyperemia / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D012307:Risk Factors; D018084:Ultrasonography, Interventional; D014664:Vasodilation