Aspergillus cholangitis: A late complication after Kasai portoenterostomy.
Ascending bacterial cholangitis can be a recurring complication in older children and adolescents who have undergone successful surgery for biliary atresia. The authors describe a 19-year-old girl with a history of recurrent late-onset, febrile cholangitis in whom persistent jaundice developed. Aspergillus terreus was isolated from her biliary fluid obtained at percutaneous transhepatic cholangiography. Despite prolonged external biliary drainage and systemic amphotericin B therapy, the fungus was not eliminated from her biliary system. Aspergillus cholangitis can occur in the portoenterostomy patient and may be highly resistant to conventional therapy.
Erdman
Steven H
SH
Sections of Gastroenterology & Nutrition and Infectious Diseases, the Department of Pediatrics, Steele Memorial Children's Research Center, University of Arizona, Tucson, AZ, USA.
Barber
Brent J
BJ
Barton
Leslie L
LL
D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002761:Cholangitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004766:Enterostomy / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006932:Hyperbilirubinemia / Q000601:surgery; D007223:Infant