TMS triflate-catalyzed cleavage of prenyl (3-methylbut-2-enyl) ester.
[reaction: see text] Prenyl (3-methylbut-2-enyl) ester is catalytically cleaved by TMS triflate affording carboxylic acid and isoprene in high yield under mild conditions with high chemoselectivity without causing epimerization of the neighboring chiral center.
Nishizawa
Mugio
M
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. mugi@ph.bunri-u.ac.jp
Yamamoto
Hirofumi
H
Seo
Ken
K
Imagawa
Hiroshi
H
Sugihara
Takumichi
T