title: Innovative medical management with resection for successful treatment of pulmonary mucormycosis despite diagnostic delay.
abstract: We present a case of primary pulmonary mucormycosis infection in a renal transplant recipient diagnosed serendipitously by computed tomography scan. Treatment included discontinuation of immunosuppressive regimen, initiation of antifungal therapy with amphotericin B lipid complex, administration of granulocyte-macrophage colony stimulating factor, surgical excision of the involved lobe, and outpatient treatment with amphotericin B with dialysis. The patient ultimately required transplant nephrectomy as a result of immunosuppression discontinuation.
authors.affiliation: Surgery Department, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.
authors.forename: Karen M
authors.initials: KM
authors.lastname: MacKenzie
authors.forename: Katherine L
authors.initials: KL
authors.lastname: Baumgarten
authors.forename: Boyd M
authors.initials: BM
authors.lastname: Helm
authors.forename: P Michael
authors.initials: PM
authors.lastname: McFadden
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Deduska
authors.forename: George E
authors.initials: GE
authors.lastname: Loss
authors.forename: James D
authors.initials: JD
authors.lastname: Eason
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents; D016030:Kidney Transplantation; D008172:Lung Diseases, Fungal / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D011013:Pneumonectomy; D011859:Radiography
chemical_list: D000935:Antifungal Agents; D007166:Immunosuppressive Agents; D000666:Amphotericin B; D016178:Granulocyte-Macrophage Colony-Stimulating Factor