Future of melatonin as a therapeutic agent.
Report of the round table conference summarizing the International Symposium on "Melatonin: Clinical Significance and Therapeutic Applications" is presented in this article. Some sleep disorders and circadian rhythm disturbances are the widely accepted indications for melatonin treatment. However, other possibilities for use of melatonin in the therapy should be also taken into account, including a co-treatment in cancer patients and free radical-related diseases. All aspects of the possible therapeutic use of melatonin as well as its safety, dosage, side effects and contraindications are discussed herein based on the round table conference and they are presented in this paper.
Karasek
Michal
M
Clinic of Endocrinology, Polish Mother's Memorial Hospital - Research Institute, Lodz, Poland. karasek@csk.am.lodz.pl
Reiter
Russel J
RJ
Cardinali
Daniel P
DP
Pawlikowski
Marek
M
D000818:Animals; D000075202:Contraindications; D016166:Free Radical Scavengers; D006801:Humans; D008550:Melatonin / Q000009:adverse effects / Q000627:therapeutic use*; D012893:Sleep Wake Disorders / Q000188:drug therapy
D016166:Free Radical Scavengers; D008550:Melatonin