title: The prevalence of high-grade prostatic intraepithelial neoplasia in surgical resection specimens: an Indian experience.
abstract: BACKGROUND
  To the authors' knowledge there is a paucity of literature regarding the prevalence of high-grade prostatic intraepithelial neoplasia (HGPIN) in the Indian subcontinent. The objective of the current study was to document the prevalence of HGPIN in a low-risk Indian population.
  
  
  METHODS
  SA total of 110 prostate specimens (61 taken from the test group and 49 taken from the control group) were studied to document the prevalence of HGPIN in a low-risk Indian population.
  
  
  RESULTS
  None of the benign prostate samples were found to harbor HGPIN, whereas 85.24% of the samples from malignant prostates did so.
  
  
  CONCLUSIONS
  SA strong correlation between HGPIN and invasive carcinoma was observed, a finding that reinforces the view that HGPIN is a strong indicator of concurrent invasive prostate carcinoma.
authors.affiliation: Department of Pathology, Tata Memorial Hospital, Mumbai, India. sangeetabdesai@rediffmail.com
authors.forename: Sangeeta B
authors.initials: SB
authors.lastname: Desai
authors.forename: Anita M
authors.initials: AM
authors.lastname: Borges
mesh_terms: D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D019048:Prostatic Intraepithelial Neoplasia / Q000453:epidemiology*; D011471:Prostatic Neoplasms / Q000453:epidemiology*