Malignant rhabdoid tumour of the kidney occurring simultaneously with a brain tumour: a report of two cases and review of the literature.
Malignant rhabdoid tumour of the kidney (MRTK), an uncommon aggressive neoplasm of children, is now recognised as a separate entity from Wilms' tumour with distinct clinical and pathological features. MRTK is unique in its significant association with primary brain tumours or brain metastases. We report two cases, aged 2 and 6 months, of MRTK occurring concurrently with a brain tumour. Radical nephrectomy and ventriculo-peritoneal shunting were performed. Both patients expired 2 and 6 months later despite receiving aggressive post-operative chemotherapy and radiotherapy.


CONCLUSIONS
malignant rhabdoid tumour of the kidney is an uncommon neoplasm of early childhood with a poor prognosis. Due to its significant association with brain tumours or early brain metastases, concurrent brain computer tomographic examination is essential for all patients with this disease.
Luo
Chih-Cheng
CC
Department of Paediatric Surgery, Chang Gung Children's Hospital, 5 Fu-Hsin Street, Kweishan 333, Taoyuan, Taiwan. lifen@adm.cgmh.org.tw
Lin
Jer-Nan
JN
Jaing
Tang-Her
TH
Yang
Chao-Ping
CP
Hsueh
Chuen
C
D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary; D018335:Rhabdoid Tumor / Q000473:pathology*; D018227:Sarcoma, Clear Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed