title: Glomerulocystic kidney disease (GCKD) associated with Henoch-Schoenlein purpura: a case report and a review of adult cases of GCKD.
abstract: We report on a 71-year-old male with Henoch-Schoenlein purpura (HSP) who developed glomerulocystic kidney disease (GCKD) without congenital abnormality. He had mild renal dysfunction. Renal biopsy findings showed mild proliferation of mesangial cells and matrixes, and tubular atrophy, interstitial fibrosis, cystic dilation of Bowman's capsule and atrophy of the glomerular tuft. The deposition of IgA and C3 in the mesangial area was observed with the fluorescent antibody technique. Therefore he was diagnosed with GCKD-associated HSP. This was the oldest patient among the previous case reports and the patient was the first case to be reported for concurrent GCKD and HSP. In this study, we also reviewed the patient to previously reported adult patients with GCKD.
authors.affiliation: Second Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Miyazaki
authors.forename: M
authors.initials: M
authors.lastname: Miyazaki
authors.forename: N
authors.initials: N
authors.lastname: Yoshizuka
authors.forename: O
authors.initials: O
authors.lastname: Sasaki
authors.forename: A
authors.initials: A
authors.lastname: Furusu
authors.forename: Y
authors.initials: Y
authors.lastname: Horita
authors.forename: T
authors.initials: T
authors.lastname: Taguchi
authors.forename: T
authors.initials: T
authors.lastname: Harada
authors.forename: Y
authors.initials: Y
authors.lastname: Ozono
authors.forename: S
authors.initials: S
authors.lastname: Kohno
mesh_terms: D000368:Aged; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications* / Q000175:diagnosis; D052177:Kidney Diseases, Cystic / Q000150:complications* / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology*; D008297:Male