HIV-1 subtype J recombinant viruses in Spain.
Genetic characterization of HIV-1 was carried out in two women who originated in Cameroon and Equatorial Guinea, respectively, and who were diagnosed more recently as HIV-1 seropositive in Madrid, Spain. Phylogenetic studies showed that the protease-encoding gene from both individuals clustered with subtype J sequences with a high bootstrap. However, env sequences clustered with subtypes A and C, respectively. This work represents the first characterization of HIV-1 containing subtype J-like genomic regions in Spain.
Holguín
Africa
A
Service of Infectious Diseases, Hospital Carlos III, Instituto de Salud Carlos III, 28035 Madrid, Spain.
Alvarez
Amparo
A
Soriano
Vincent
V
D001483:Base Sequence; D002163:Cameroon; D016703:Equatorial Guinea; D005260:Female; D015686:Gene Products, env / Q000235:genetics*; D015658:HIV Infections / Q000175:diagnosis / Q000821:virology; D016333:HIV Protease / Q000235:genetics*; D015497:HIV-1 / Q000145:classification* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D010802:Phylogeny; D013030:Spain
D015686:Gene Products, env; D016333:HIV Protease