Role of adrenal stress hormones in forming lasting memories in the brain.
Recent experiments investigating the effects of adrenal stress hormones on memory provide extensive evidence that epinephrine and glucocorticoids modulate long-term memory consolidation in animals and human subjects. Release of norepinephrine and activation of beta-adrenoceptors within the basolateral amygdala is critical in mediating adrenal stress hormone regulation of memory consolidation.
McGaugh
James L
JL
Center for the Neurobiology of Learning and Memory and Department of Neurobiology and Behavior, University of California, Irvine, California 92697-3800, USA.
Roozendaal
Benno
B
D000305:Adrenal Cortex Hormones / Q000378:metabolism* / Q000502:physiology; D000679:Amygdala / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D001921:Brain / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D005938:Glucocorticoids / Q000378:metabolism; D006801:Humans; D008568:Memory; D011941:Receptors, Adrenergic / Q000378:metabolism; D013315:Stress, Psychological / Q000378:metabolism*
D000305:Adrenal Cortex Hormones; D005938:Glucocorticoids; D011941:Receptors, Adrenergic; D004837:Epinephrine