Two new steroidal saponins from "Gualou-xiebai-baijiu-tang" consisting of Fructus trichosanthis and Bulbus allii macrostemi.
Two new steroidal saponins were isolated from the Chinese folk medicine called Gualou-xiebai-baijiu-tang. The structures were determined to be spirost 25(27)-ene-2beta,3beta-diol-3-O-beta-D-glucopyranosyl(1-->2)-beta-D-galactopyranoside and 26-O-beta-D-glucopyranosyl-22alpha-hydroxy-5beta-furost-25(27)-ene-1beta,3beta,6beta,26-tetraol-3-O-beta-D-galactopyranoside, respectively, based on chemical evidences and spectral analysis.
He
Xiangjiu
X
Department of Natural Products Chemistry, Shenyang Pharmaceutical University, P R China.
Qiu
Feng
F
Shoyama
Yukihiro
Y
Tanaka
Hiroyoki
H
Yao
Xinsheng
X
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006868:Hydrolysis; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D010974:Platelet Aggregation / Q000187:drug effects; D011817:Rabbits; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013141:Spiro Compounds / Q000737:chemistry* / Q000302:isolation & purification
C468042:25(27)-ene-2,3-diol-3-O-glucopyranosyl(1-2)-galactopyranoside; C468041:26-O-glucopyranosyl-22alpha-hydroxy-5-furost-25(27)-ene-1,3,6,26-tetraol-3-O-galactopyranoside; D004365:Drugs, Chinese Herbal; D012503:Saponins; D013141:Spiro Compounds