title: [Changing susceptibility patterns of surgical site infection pathogens after the introduction of modern perioperative chemotherapy in the emergency surgery clinic].
abstract: 993 surgical site infection aerobic pathogens are isolated over a six-year period (I.1994-I.2000) by the Microbiology Laboratory at University Hospital "Tzaritza Joana". 224 (22.6%) of them are isolated from patients undergoing abdominal surgery in the Emergency Surgery Clinic. The period covers 3 years before the introduction of current single-dose perioperative prophylaxis (i.e. under the conditions of long-term one) as well as the next 3 years following its introduction in the Emergency Surgery Clinic. The changes of pathogens susceptibility patterns to single-dose drug schemes in both hospital elective abdominal surgery and emergency surgery clinics are followed during the whole period. Our microbial susceptibility data support the ecological expedience of single-dose approach categorically.
authors.forename: D
authors.initials: D
authors.lastname: Tonev
authors.forename: D
authors.initials: D
authors.lastname: Viiachki
authors.forename: I
authors.initials: I
authors.lastname: Viiachki
authors.forename: D
authors.initials: D
authors.lastname: Ivanova
authors.forename: N
authors.initials: N
authors.lastname: Khadzhieva
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000900:Anti-Bacterial Agents; D019072:Antibiotic Prophylaxis / Q000379:methods* / Q000706:statistics & numerical data; D001420:Bacteria, Aerobic / Q000302:isolation & purification; D002031:Bulgaria; D004334:Drug Administration Schedule; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D017558:Elective Surgical Procedures; D004636:Emergency Service, Hospital; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006785:Hospitals, University; D006801:Humans; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative / Q000379:methods* / Q000706:statistics & numerical data; D013530:Surgical Wound Infection / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents