Synthesis of new pyrroles and their biological activities.
Coumarino acid hydrazides and acid hydrazide of 2-oxy 3, 5, 6-trichloropyridine were prepared in two steps. These acid hydrazides on condensation with Acetonyl acetone i.e. 2,5-hexanedione yields new pyrroles. These pyrroles showed good to moderate antimicrobial activities against Alternaria brassicicola, Aspergillus niger, E. coli and Lactobacillus.
Chavan
V P
VP
Department of Chemistry, Dr. B. A. Marathwada University, Aurangabad 431 004, India.
Mane
A S
AS
Bhawsar
S B
SB
Hangarge
R V
RV
Shingare
M S
MS
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000639:trends; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology*
D000890:Anti-Infective Agents; D000935:Antifungal Agents; D011758:Pyrroles