title: Intravascular-ultrasound-guided percutaneous transluminal coronary angioplasty/provisional stent implantation strategy: impact on long-term clinical follow-up.
abstract: Two hundred and eighty-four consecutive patients with 438 native coronary artery stenoses were enrolled prospectively in a study of intravascular ultrasound (IVUS)-guided percutaneous transluminal coronary angioplasty (PTCA) with provisional stenting: (1) aggressive lesion-site media-to-media balloon-sizing; (2) IVUS-assessment of residual lumen dimensions to identify optimal PTCA results (minimum lumen area = 65% of the average of the proximal and distal reference lumen areas or = 6.0 mm(2) and no major dissection); and (3) liberal stent crossover. Overall, 206 stenoses in 134 patients (47%) were treated with PTCA alone. Reasons for crossover were flow-limiting or lumen-compromising dissections in 28% of patients and suboptimal IVUS minimum lumen area in 72% of patients. At one year, 8% of stenoses in the PTCA group and 16% in the stent crossover group required revascularization. In approximately half of the patients treated using an IVUS-guided aggressive PTCA strategy, stent implantation could be avoided without sacrificing an increase in acute complications or worse clinical outcome.
authors.affiliation: Department of Cardiology, Institute Dante Pazzaneze, São Paulo, Brazil.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Abizaid
authors.forename: Augusto D
authors.initials: AD
authors.lastname: Pichard
authors.forename: Gary S
authors.initials: GS
authors.lastname: Mintz
authors.forename: Andrea S
authors.initials: AS
authors.lastname: Abizaid
authors.forename: Roxana
authors.initials: R
authors.lastname: Mehran
authors.forename: Amanda
authors.initials: A
authors.lastname: Sousa
authors.forename: Eduardo
authors.initials: E
authors.lastname: Sousa
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon