title: [Scintigraphic assessment of the small intestine transit. Diagnostic investigation of dysmotility with 99mTc-HIDA].
abstract: Symptoms from the gastro-intestinal tract are common and often difficult to evaluate. Specialised examination techniques are available only at a limited number of clinics. A technique based on biliary scintigraphy when measuring the transit of contents through the small intestine has been developed. The investigation is simple to perform and convenient for the patient. It can be carried out at any clinic equipped with a gamma camera. 30 healthy individuals were examined in order to obtain reference values. 23 patients were examined with scintigraphy in combination with upper gastrointestinal manometry, 10 of whom had abdominal pain and neurogenic or myogenic pseudoobstruction disclosed by manometry. In another 4 patients, slow transit and pain prevailed in conjunction with normal manometric findings. Rapid transit and diarrhoea was found in 3 patients with various abberations on manometry. Of the remaining patients, 4 had slow transit and diarrhoea with intestinal neuropathy and pseudoobstruction, and 2 had slow transit along with endocrinopathies (diabetes, pituitary insufficiency).
authors.affiliation: Sektionen för nuklearmedicin (avdelningen för sjukhusfysik), avdelningen för diagnostisk radiologi, Karolinska sjukhuset, Stockholm. per.gryback@ks.se
authors.forename: Per
authors.initials: P
authors.lastname: Grybäck
authors.forename: Lars
authors.initials: L
authors.lastname: Blomquist
authors.forename: P O
authors.initials: PO
authors.lastname: Schnell
authors.forename: Hans
authors.initials: H
authors.lastname: Jacobsson
authors.forename: Per M
authors.initials: PM
authors.lastname: Hellström
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D000328:Adult; D000368:Aged; D001944:Breath Tests; D003967:Diarrhea / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology; D005772:Gastrointestinal Transit / Q000502:physiology; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D007418:Intestinal Pseudo-Obstruction / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D007421:Intestine, Small / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012016:Reference Values; D019780:Technetium Tc 99m Lidofenin
chemical_list: D019275:Radiopharmaceuticals; D019780:Technetium Tc 99m Lidofenin