Tumor-associated tissue eosinophilia of penile cancer.
BACKGROUND
Tumor-associated tissue eosinophilia (TATE) occurs in many kinds of cancer. This study analyzed whether TATE improves the survival of penile cancer patients.


METHODS
In 17 patients with penile cancer, survival was compared between the TATE-positive group and the TATE-negative group. Tissue eosinophils were observed by transmission electron microscopy.


RESULTS
In all cases, 5-year survival was 72.9% in the TATE-positive group (n = 8) and 38.9% in the TATE-negative group (n = 9; P = 0.131). In stage III and IV, it was 60% in the TATE-positive group (n = 5) and 0% in the TATE-negative group (n = 5; P = 0.058). Transmission electron microscopy images revealed the vigorous infiltration of tissue eosinophils.


CONCLUSIONS
It is suggested that TATE improves the survival of patients with advanced penile cancer. However, a greater number of subjects is needed to prove statistical significance.
Ono
Yoshihiro
Y
Department of Urology, Gunma Cancer Center, Gunma University, School of Medicine, Japan. yoshi@econett.co.jp
Ozawa
Masashi
M
Tamura
Yoshimi
Y
Suzuki
Takanori
T
Suzuki
Kazuhiro
K
Kurokawa
Kohei
K
Fukabori
Yoshitatsu
Y
Yamanaka
Hidetoshi
H
D004802:Eosinophilia / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D010412:Penile Neoplasms / Q000150:complications / Q000401:mortality* / Q000473:pathology; D015996:Survival Rate