A study to evaluate the antimicrobial activity of feracrylum and its comparison with povidone-iodine.
Feracrylum, a water-soluble polymer of polyacrylic acid is known for its hemostatic property. Present work is an effort to evaluate its minimum inhibitory concentration (MIC) and compare it with the MIC of povidone-iodine. Ten different species of pathogenic microorganisms were selected, strains of which were obtained from Haffkine Institute. The organisms were maintained under appropriate culture media. The MIC of Freracrylum was determined by using tube culture method where its activity was compared against a standard antimicrobial agent providone-iodine. The study parameters showed that Feracrylum exhibits antimicrobial activity against a wide variety of microorganisms and its efficacy is comparable to that of povidone-iodine.
Bhagwat
A M
AM
Themis Chemicals Limited, CB Patel Research Centre, Mumbai.
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Burli
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Karki
S G
SG
D000180:Acrylic Resins / Q000494:pharmacology*; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D011206:Povidone-Iodine / Q000494:pharmacology*; D014242:Trichoderma / Q000187:drug effects*
D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; C049492:Feracryl; D011206:Povidone-Iodine