Ether phospholipids affect mast cell histamine release with relative potency similar to that with leukocyte membrane Ca2+-ATPase activity.
Grosman
Nina
N
Department of Pharmacology, The Panum Institute, University of Copenhagen, Denmark. fipe@farmakol.ku.dk
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D000001:Calcimycin / Q000494:pharmacology; D000252:Calcium-Transporting ATPases / Q000037:antagonists & inhibitors*; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006636:Histamine Release / Q000187:drug effects*; D066298:In Vitro Techniques; D007962:Leukocytes / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000378:metabolism*; D010742:Phospholipid Ethers / Q000494:pharmacology*; D010743:Phospholipids / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D003189:p-Methoxy-N-methylphenethylamine / Q000037:antagonists & inhibitors / Q000494:pharmacology
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D010742:Phospholipid Ethers; D010743:Phospholipids; C026659:edelfosine; D000001:Calcimycin; D003189:p-Methoxy-N-methylphenethylamine; C050186:1-hexadecyl-2-methoxyglycero-3-phosphocholine; D000252:Calcium-Transporting ATPases