title: Vessel contrast at three Tesla in time-of-flight magnetic resonance angiography of the intracranial and carotid arteries.
abstract: The effects of the increased field strength of 3T on blood vessel contrast in three-dimensional time-of-flight (TOF) MR angiography (MRA) of the intracranial and carotid arteries was evaluated. Bloch equation simulations based on measured longitudinal relaxation times suggested superior blood-to-background contrast might be expected at 3T over 1.5T when using typical 3D TOF MRA parameters. A 15-volunteer study found that 3T was preferable over 1.5T for visualising distal intracranial vessels and the carotid arteries, by providing superior background suppression and excellent fat suppression. The combination of improved background suppression and improved signal-to-noise at 3T, enabled high resolution intracranial 3D TOF MRA with voxel volumes as small as 0.14 mm(3) to be acquired.
authors.affiliation: Departments of Biomedical Engineering, and Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Canada T6G 2G3.
authors.forename: Osama
authors.initials: O
authors.lastname: Al-Kwifi
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Emery
authors.forename: Alan H
authors.initials: AH
authors.lastname: Wilman
mesh_terms: D000328:Adult; D002339:Carotid Arteries / Q000033:anatomy & histology*; D002941:Circle of Willis / Q000033:anatomy & histology*; D006801:Humans; D018810:Magnetic Resonance Angiography; D013997:Time Factors