Comparison of the ESP and BACTEC systems for testing susceptibilities of Mycobacterium tuberculosis complex isolates to pyrazinamide.
Fifty isolates of Mycobacterium tuberculosis complex were tested for susceptibility to pyrazinamide (PZA) by the ESP (Trek Diagnostic Systems, Westlake, Ohio) and BACTEC (BD Biosciences, Sparks, Md.) test systems. Initial results showed concordance for 48 of the isolates. On retest, the two discordant isolates were resolved in favor of the ESP system. The ESP Myco susceptibility test system generates rapid, reliable PZA test results.
LaBombardi
Vincent J
VJ
Department of Laboratories, St. Vincent's Hospital Manhattan, New York, New York 10011, USA.
D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology*; D002417:Cattle; D003470:Culture Media; D024881:Drug Resistance, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D009163:Mycobacterium bovis / Q000187:drug effects*; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D011718:Pyrazinamide / Q000494:pharmacology*; D011874:Radiometry; D012680:Sensitivity and Specificity
D000995:Antitubercular Agents; D003470:Culture Media; D011718:Pyrazinamide