Mechanisms of allorecognition and organ transplant rejection.
Recognition of mismatched (foreign) alloantigens on the graft by the recipients T cells initiates allograft rejection. This process is mediated by two mayor mechanisms--direct and indirect allorecognition. Both process are being discussed.
Slavcev
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Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic. tosl@medicon.cz
D006084:Graft Rejection; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D016377:Organ Transplantation; D013601:T-Lymphocytes / Q000276:immunology*; D014181:Transplantation Immunology
D006680:HLA Antigens