[Cardiovascular responses to emotional stress during activation of the brain imidazoline receptors].
In alert normotensive and hypertensive (SHR) rats, effects of imidazoline receptor activating compounds of the central nervous system on the level of blood pressure, heart rate and value of arterial baroreceptor reflex at rest and in emotional tension, were investigated. It was shown, that the activation of the cerebral imidazoline receptors leads to an increase in the baroreceptor reflex value (both in resting and in emotional tension) and a decrease in the pressor reaction evoked by emotional affect. No data showing the role of imidazoline receptors in functioning of systems regulating of the initial level of blood pressure were obtained.
Kuz'menko
N V
NV
Research Institute of Cardiology, Russia, 194156, St. Petersburgr, Pr. Parkhomenko, 15.
Pliss
M G
MG
Tsyrlin
V A
VA
D000322:Adrenergic Agonists / Q000494:pharmacology; D000818:Animals; D017704:Baroreflex / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects*; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D006339:Heart Rate / Q000187:drug effects*; D006439:Hemodynamics / Q000187:drug effects; D054755:Imidazoline Receptors; D008297:Male; D051381:Rats; D011918:Rats, Inbred SHR; D018341:Receptors, Adrenergic, alpha-2 / Q000187:drug effects / Q000502:physiology; D011955:Receptors, Drug / Q000819:agonists* / Q000502:physiology; D013045:Species Specificity; D013315:Stress, Psychological / Q000503:physiopathology*
D000322:Adrenergic Agonists; D054755:Imidazoline Receptors; D018341:Receptors, Adrenergic, alpha-2; D011955:Receptors, Drug