title: Poor-quality medical research: what can journals do?
abstract: The aim of medical research is to advance scientific knowledge and hence--directly or indirectly--lead to improvements in the treatment and prevention of disease. Each research project should continue systematically from previous research and feed into future research. Each project should contribute beneficially to a slowly evolving body of research. A study should not mislead; otherwise it could adversely affect clinical practice and future research. In 1994 I observed that research papers commonly contain methodological errors, report results selectively, and draw unjustified conclusions. Here I revisit the topic and suggest how journal editors can help.
authors.affiliation: Cancer Research UK/NHS Centre for Statistics in Medicine, Institute of Health Sciences, Old Road, Headington, Oxford OX3 7LF, England. doug.altman@cancer.org.uk
authors.forename: Douglas G
authors.initials: DG
authors.lastname: Altman
mesh_terms: D017712:Peer Review, Research; D017594:Publication Bias; D016032:Randomized Controlled Trials as Topic; D012107:Research Design