title: Impact of linear alkyl benzene sulphonate (LAS) on phosphatase activity in testis of the teleostean fish, Heteropneustes fossilis (Bloch).
abstract: Fishes are sensitive indicators of pollutants present in water.These pollutants cause various physical and physiological alterations in fishes. In the present work alteration in the activity of acid and alkaline phosphatase was evaluated in testicular tissue of fresh water fish Heteropneustes fossilis exposed to LC50 value of linear alkyl benzene sulphonate (LAS) for different exposure periods [24 h, 48 h, 72 h and 96 h] With increase in the concentration of chemical LAS, the activity of acid phosphatase (ACP) was reported elevated while a significant fall in the activity of alkaline phosphatase (ACP) was recorded for same exposure period. Elevated activity of ACP, one of the important hydrolases of lysosomes, is quite suggestive of bringing about gross necrosis and dysarchitecture. ALP is involved in various metabolic activities including gonadal maturation and as such decreased activity of this enzyme is definitely one of the important causative factors for reproductive impairment of the fish.
authors.affiliation: Department of Zoology, University of Lucknow, India. sat060523@rediffmail.com
authors.forename: S P
authors.initials: SP
authors.lastname: Trivedi
authors.forename: M
authors.initials: M
authors.lastname: Kumar
authors.forename: A
authors.initials: A
authors.lastname: Mishra
authors.forename: I
authors.initials: I
authors.lastname: Banerjee
authors.forename: A
authors.initials: A
authors.lastname: Soni
mesh_terms: D000135:Acid Phosphatase / Q000187:drug effects / Q000494:pharmacology*; D000469:Alkaline Phosphatase / Q000187:drug effects / Q000494:pharmacology*; D017738:Alkanesulfonic Acids / Q000009:adverse effects*; D000818:Animals; D002397:Catfishes / Q000502:physiology*; D007928:Lethal Dose 50; D008247:Lysosomes; D008297:Male; D013501:Surface-Active Agents / Q000009:adverse effects*; D013737:Testis / Q000201:enzymology; D014874:Water Pollutants, Chemical / Q000009:adverse effects*
chemical_list: D017738:Alkanesulfonic Acids; D013501:Surface-Active Agents; D014874:Water Pollutants, Chemical; C030641:alkylbenzyl sulfonic acid; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase