Innovative medical management with resection for successful treatment of pulmonary mucormycosis despite diagnostic delay.
We present a case of primary pulmonary mucormycosis infection in a renal transplant recipient diagnosed serendipitously by computed tomography scan. Treatment included discontinuation of immunosuppressive regimen, initiation of antifungal therapy with amphotericin B lipid complex, administration of granulocyte-macrophage colony stimulating factor, surgical excision of the involved lobe, and outpatient treatment with amphotericin B with dialysis. The patient ultimately required transplant nephrectomy as a result of immunosuppression discontinuation.
MacKenzie
Karen M
KM
Surgery Department, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.
Baumgarten
Katherine L
KL
Helm
Boyd M
BM
McFadden
P Michael
PM
Deduska
Nicholas J
NJ
Loss
George E
GE
Eason
James D
JD
D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents; D016030:Kidney Transplantation; D008172:Lung Diseases, Fungal / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D011013:Pneumonectomy; D011859:Radiography
D000935:Antifungal Agents; D007166:Immunosuppressive Agents; D000666:Amphotericin B; D016178:Granulocyte-Macrophage Colony-Stimulating Factor