[The loss of endothelial cells after perforating keratoplasty--clinical study].
OBJECTIVE
To determine endothelial cell loss rate after penetrating keratoplasty. To determine for low long this rate remain high.


METHODS
We have three groups of patients. First group consists of 15 patients without ophthalmic pathology. The second group consists of 15 patients, after cataract surgery. The Third group consists of 20 patients after penetrating keratoplasty, 10 of them with edematous keratoplasty and 10 with keratoconus or central leucoma. Every patient was examined with direct specular microscopy, after 1, 3, 6, 9, 12, 15 and 18 months.


RESULTS
In the first group we can't determine an endothelial cell loss. In the second group the endothelial cell loss was 4% per month, 5.9% per month, then the value become normal. In the third endothelial cell was continuous within all intervals.


CONCLUSIONS
After penetrating keratoplasty there is a significant endothelial cell loss that continues over 18 month.
Zemba
M
M
Räncea
C
C
Bobeico
V
V
Ciucă
C
C
Brătulescu
M
M
Mazilu
M
M
D002452:Cell Count; D002470:Cell Survival / Q000502:physiology*; D004728:Endothelium, Corneal / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D011183:Postoperative Complications / Q000473:pathology*