The 3D's of apoptosis: death, degradation and DIAPs.
Inhibitor of apoptosis proteins (IAPs) are critical regulators of apoptosis. Recent evidence suggests that in some situations, induction of apoptosis initiates general repression of translation, as well as the targeted ubiquitination and degradation of IAPs.
Palaga
Tanapat
T
Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA.
Osborne
Barbara
B
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D029721:Drosophila Proteins / Q000378:metabolism*; D051034:Inhibitor of Apoptosis Proteins; D014176:Protein Biosynthesis / Q000502:physiology*; D025801:Ubiquitin / Q000378:metabolism
C111891:DIAP1 protein, Drosophila; D029721:Drosophila Proteins; D051034:Inhibitor of Apoptosis Proteins; D025801:Ubiquitin