[Effect of products of alphaS1-casein proteolysis on the activity of angiotensin-converting enzyme].
The influence of alpha s1-casein proteolysis products of cow milk on the activity of angiotensin-converting enzyme (ACE) has been investigated. The peptide fraction has been obtained after incubation of alpha s1-casein with different strains Lactococcus lactis ssp. lactis and pepsin. The peptides with low molecular weight has been obtained with the help of a gel filtration. It is shown, that such peptides received with the help of some strains of Lactococcus lactis ssp. lactis and pepsin are capable to inhibit the activity of ACE. A conclusion about possibility of appearing antihypertensive peptides as a result of proteolitic processes in milk products has been made.
Iukalo
V H
VH
Puluy Technical State University, Ternopil, Ukraine. biotech@tu.edu.te.ua
D002364:Caseins / Q000378:metabolism*; D002850:Chromatography, Gel; D006868:Hydrolysis; D013294:Lactococcus lactis / Q000378:metabolism; D010434:Pepsin A / Q000378:metabolism; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*
D002364:Caseins; D007703:Peptidyl-Dipeptidase A; D010434:Pepsin A