Potentiating potassium nitrate's desensitization with dimethyl isosorbide.
Desensitization of hypersensitive teeth by the combination of dimethyl isosorbide (DMI) and potassium nitrate (KNO3) is more effective than when KNO3 is used alone. KNO3/DMI work together to desensitize hypersensitive teeth at a higher, quicker, and more profound and lasting level.
Hodosh
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D000328:Adult; D003080:Cold Temperature; D003802:Dentifrices / Q000627:therapeutic use; D003804:Dentin / Q000187:drug effects; D003807:Dentin Sensitivity / Q000145:classification / Q000188:drug therapy*; D004338:Drug Combinations; D004357:Drug Synergism; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007547:Isosorbide / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D009566:Nitrates / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D010710:Phosphates / Q000627:therapeutic use; D017680:Potassium Compounds / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D018709:Statistics, Nonparametric; D013997:Time Factors; D014099:Toothbrushing / Q000295:instrumentation; D014110:Touch / Q000187:drug effects
D003802:Dentifrices; D004338:Drug Combinations; D009566:Nitrates; D010710:Phosphates; D017680:Potassium Compounds; C097427:Sensodyne; D005459:Fluorides; C023844:potassium nitrate; D007547:Isosorbide