title: [The effect of the intra- and extracellular metabolites of microorganisms isolated from various ecotopes on the catalase activity of Staphylococcus aureus 6538P].
abstract: The cell extracts (i.e., intracellular metabolites) and culture liquids (i.e., extracellular metabolites) of microorganisms isolated from various ecotopes were found to inhibit the catalase activity of Staphylococcus aureus ATCC 6538P, which resulted in a considerable inhibition of the growth of metabolite-treated S. aureus cells by hydrogen peroxide. The inhibitory effect of microbial metabolites on S. aureus catalase can be considered as a mechanism of intercellular interactions responsible for the formation of microbiocenoses.
authors.affiliation: Institute of Cellular and Intracellular Symbiosis, Ural Division, Russian Academy of Sciences, ul. Pionerskaya 11, Orenburg, 460000 Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Bukharin
authors.forename: A V
authors.initials: AV
authors.lastname: Sgibnev
authors.forename: S V
authors.initials: SV
authors.lastname: Cherkasov
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Ivanov
mesh_terms: D001685:Biological Factors / Q000494:pharmacology*; D002374:Catalase / Q000037:antagonists & inhibitors*; D003470:Culture Media; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000201:enzymology* / Q000254:growth & development
chemical_list: D001685:Biological Factors; D003470:Culture Media; D004791:Enzyme Inhibitors; D006861:Hydrogen Peroxide; D002374:Catalase