title: The effects of dentin permeability on restorative dentistry.
abstract: The permeability properties of dentin determine its sensitivity and the degree of pulpal response to restorative procedure materials and microleakage. Most pulpal reactions are due to bacteria or bacterial products that permeate across dentin. These reactions can be prevented if dentin is sealed with resins as soon as it is exposed. In the future, restorative dentists may employ topical application of biologic growth factors to permeate across dentin to modify the formation of reactionary or reparative dentin, thereby lowering dentin permeability and protecting the pulp.
authors.affiliation: Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, GA 30912-1129, USA. dpashley@mail.mcg.edu
authors.forename: David H
authors.initials: DH
authors.lastname: Pashley
authors.forename: Edna L
authors.initials: EL
authors.lastname: Pashley
authors.forename: Ricardo M
authors.initials: RM
authors.lastname: Carvalho
authors.forename: Franklin R
authors.initials: FR
authors.lastname: Tay
mesh_terms: D003763:Dental Leakage / Q000150:complications; D003793:Dental Restoration, Permanent / Q000009:adverse effects*; D003806:Dentin Permeability; D003807:Dentin Sensitivity / Q000209:etiology*; D003809:Dentin, Secondary / Q000502:physiology; D019234:Dentinal Fluid / Q000502:physiology; D006133:Growth Substances / Q000502:physiology; D006801:Humans; D019279:Resin Cements / Q000009:adverse effects
chemical_list: D006133:Growth Substances; D019279:Resin Cements