Nomograms for clinically localized prostate cancer. Part I: radical prostatectomy.
Many nomograms are currently available for patients' and physicians' use for prediction of pathologic stage based on preoperative parameters, such as prostate-specific antigen (PSA) level, clinical stage (tumor, node, metastasis), and Gleason score from prostate biopsy specimen. Based on the probability of final pathologic stage as well as patient comorbidity and life expectancy, patients and physicians can decide whether definitive local therapy, systemic therapy, or palliative therapy would be most appropriate. Nomograms have also been developed based on preoperative parameters for prediction of biochemical recurrence-free survival outcome following surgery. These nomograms can help patients understand the long-term cancer cure rates after radical prostatectomy.
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James Buchanan Brady Urological Institute, the Department of Urology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
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Alan W
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D000465:Algorithms; D006801:Humans; D008017:Life Expectancy; D008297:Male; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D016571:Neural Networks, Computer; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate
D017430:Prostate-Specific Antigen