[Captopril angioscintigraphic test in the screening for renovascular hypertension in the light of long-term own observation (1098-2001)].
In 430 patients (pts) with hypertension (209F + 221M, mean age 46 +/- 13 yrs) screening value of the captopril angioscintigraphic test (CAT) was evaluated in years 1986-2001 in the diagnosis of renovascular hypertension (RVHT). Captopril renin test (CRT) and CAT were performed simultaneously in all 430 pts. Classical renal angiography was performed in 95 pts suspected for RVHT on the basis of clinical anamnesis and positive result at least one of captopril tests. Results were as follows. The critical renal artery stenosis (RAS) was found in 47 pts. At least one positive captopril test was found in 42 from 47 pts with critical RAS in angiography. CRT was found to be more sensitive and CAT more specific for hemodynamically significant RAS. The absence of false positive results of CAT as well as considerable percentage of false positive results of CRT stress the importance of isotopic test as the screening test for the diagnosis of RVT. Simplicity of the test, availability as well as immediately obtained result allow to propose CAT as a routine ambulatory screening test for RVHT.
Smoszna
J
J
Stembrowicz
Z
Z
Wańkowicz
Z
Z
D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors; D002216:Captopril; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D006978:Hypertension, Renovascular / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging* / Q000209:etiology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
D000806:Angiotensin-Converting Enzyme Inhibitors; D002216:Captopril