title: Values of urine specific gravity for thoroughbred horses treated with furosemide prior to racing compared with untreated horses.
abstract: The distribution of specific gravity values for 2,599 urine samples collected from racing Thoroughbred horses that were known to have received furosemide prior to racing was compared with that for 1,669 urine samples from racing Thoroughbred horses that reportedly had not received furosemide. Values of specific gravity for furosemide-treated horses were significantly lower (P < 0.001) than those for horses that had not received furosemide, and the proportion of horses with urine specific gravity either <1.010 or <1.012 was significantly greater (P < 0.001) among the furosemide-treated horses. These data indicate that evaluation of urine specific gravity would be a useful component of drug testing programs for regulation of furosemide use.
authors.affiliation: Department of Large Animal Medicine, College of Veterinary Medicine, Texas A&M University, College Station 77843-4475, USA.
authors.forename: Noah D
authors.initials: ND
authors.lastname: Cohen
authors.forename: Kenneth E
authors.initials: KE
authors.lastname: Peck
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Smith
authors.forename: Allen C
authors.initials: AC
authors.lastname: Ray
mesh_terms: D000818:Animals; D004232:Diuretics / Q000008:administration & dosage*; D004300:Doping in Sports; D005665:Furosemide / Q000008:administration & dosage*; D006736:Horses; D012016:Reference Values; D012680:Sensitivity and Specificity; D013046:Specific Gravity
chemical_list: D004232:Diuretics; D005665:Furosemide