The ballet of morphogenesis: unveiling the hidden choreographers.
Several recent papers reveal new insights into the mechanisms by which cells turn their perceptions about fate into action, focusing on the role of Wnt signal transduction in cell polarization and migration.
Peifer
Mark
M
Department of Biology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, 27599, USA. peifer@unc.edu
McEwen
Donald G
DG
D000818:Animals; D002465:Cell Movement; D016764:Cell Polarity; D004330:Drosophila; D029721:Drosophila Proteins; D051157:Frizzled Receptors; D018507:Gene Expression Regulation, Developmental; D008565:Membrane Proteins / Q000378:metabolism; D008954:Models, Biological; D009024:Morphogenesis / Q000502:physiology*; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D043562:Receptors, G-Protein-Coupled; D015398:Signal Transduction / Q000502:physiology*; D051153:Wnt Proteins; D014981:Xenopus; D029961:Zebrafish Proteins
D029721:Drosophila Proteins; D051157:Frizzled Receptors; D008565:Membrane Proteins; D011518:Proto-Oncogene Proteins; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D051153:Wnt Proteins; D029961:Zebrafish Proteins; C058784:fz protein, Drosophila