title: Dentatorubropallidoluysian atrophy with chronic renal failure in a Japanese family.
abstract: We describe a Japanese family with molecularly confirmed DRPLA associated with chronic renal failure of unclear etiology on hemodialysis. The clinical symptoms and laboratory data show that the renal failure in our DRPLA patients is not associated with known familial renal diseases. Thus, we suggest a possible unifying hypothesis that the coexistence of DRPLA and chronic renal failure may be caused by the same etiology.
authors.affiliation: Department of Neurology, Teikyo University School of Medicine, Ichihara Hospital, Ichihara, Japan. ono@med.teikyo-u.ac.jp
authors.forename: Seiitsu
authors.initials: S
authors.lastname: Ono
authors.forename: Kenshi
authors.initials: K
authors.lastname: Kaneda
authors.forename: Megumi
authors.initials: M
authors.lastname: Suzuki
authors.forename: Asako
authors.initials: A
authors.lastname: Tagawa
authors.forename: Natsue
authors.initials: N
authors.lastname: Shimizu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000235:genetics* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D020191:Myoclonic Epilepsies, Progressive / Q000150:complications* / Q000235:genetics*; D010375:Pedigree; D006435:Renal Dialysis; D018911:Trinucleotide Repeats / Q000235:genetics