title: Use of CO2 laser in the treatment of periungual fibromas associated with tuberous sclerosis.
abstract: BACKGROUND
  Tuberous sclerosis complex is an autosomal dominant disorder with variable clinical expression. In severe forms it may involve almost any organ system. Periungual fibromas are a common cutaneous manifestation and a frequent source of cosmetic and functional concern. Current treatment involves surgical excision of the lesions.
  
  
  OBJECTIVE
  To evaluate laser vaporization of periungual fibromas and to compare results to the standard surgical treatment.
  
  
  METHODS
  A patient with tuberous sclerosis and recurrent periungual fibromas was treated with a continuous wave CO2 laser in sequential focused and defocused modes at 10-15 W.
  
  
  RESULTS
  Laser treatment required approximately 10 seconds per lesion and produced no intraoperative bleeding. The wounds healed well with good cosmetic results.
  
  
  CONCLUSIONS
  Though similar to conventional surgery in terms of cosmetic satisfaction, CO2 laser presents a viable alternative to surgery through significantly reduced treatment time and amount of bleeding.
authors.affiliation: Department of Dermatology, University of Illinois College of Medicine, Chicago, Illinois, USA.
authors.forename: Alexander L
authors.initials: AL
authors.lastname: Berlin
authors.forename: Robin C
authors.initials: RC
authors.lastname: Billick
mesh_terms: D002245:Carbon Dioxide; D005260:Female; D005350:Fibroma / Q000209:etiology / Q000601:surgery*; D005385:Fingers; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D009260:Nail Diseases / Q000209:etiology / Q000601:surgery*; D012878:Skin Neoplasms / Q000209:etiology / Q000601:surgery*; D014034:Toes; D014402:Tuberous Sclerosis / Q000150:complications*
chemical_list: D002245:Carbon Dioxide