Cloning and characterization of ZAP36, an annexin-like, zymogen granule membrane associated protein, in exocrine pancreas.
ZAP36, a zymogen granule membrane associated protein with 36 kDa, was cloned from both canine and rat pancreas. ZAP36 is found to be a novel member of annexin IV, and showed an apical localization in exocrine pancreas and an ubiquitous expression in epithelial tissues. ZAP36 may be involved in exocytosis in apical regions of polarized cells.
Fukuoka
Shin-Ichi
S
Graduate School of Agriculture, Kyoto University, Uji, Kyoto 611-0011, Japan. fukuoka@food2.kyoto-u.ac.jp
Kern
Horst
H
Kazuki-Sugino
Reiko
R
Ikeda
Yoshiki
Y
D000595:Amino Acid Sequence; D000818:Animals; D017314:Annexin A4 / Q000235:genetics* / Q000378:metabolism; D017302:Annexins / Q000235:genetics* / Q000378:metabolism; D001483:Base Sequence; D003594:Cytoplasmic Granules / Q000378:metabolism; D004285:Dogs; D008969:Molecular Sequence Data; D010179:Pancreas / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA
D017314:Annexin A4; D017302:Annexins; C459883:Anxa4 protein, rat