The association of pre-eclampsia with the Duffy negative phenotype in women of West African descent.
OBJECTIVE
To investigate whether pre-eclampsia in Curaçao is associated with the Duffy negative phenotype.


METHODS
Retrospective study.


RESULTS
Women with a history of pre-eclampsia had a higher Duffy negative phenotype frequency compared with women with a history of uncomplicated pregnancies (52.8 vs 27.3%, respectively; odds ratio 2.98; 95% CI 1.40-6.32; P = 0.004).


CONCLUSIONS
Pre-eclampsia is associated with the Duffy negative phenotype in women of West-African descent in the island of Curaçao.
Velzing-Aarts
Francien V
FV
Pathology and Laboratory Medicine, Groningen University Hospital, The Netherlands.
van der Dijs
Fey P L
FP
Muskiet
Frits A J
FA
Duits
Ashley J
AJ
D000328:Adult; D000354:Africa, Western / Q000208:ethnology; D001724:Birth Weight; D004375:Duffy Blood-Group System / Q000235:genetics*; D005260:Female; D005865:Gestational Age; D006801:Humans; D008423:Maternal Age; D010298:Parity; D010641:Phenotype; D011225:Pre-Eclampsia / Q000097:blood* / Q000235:genetics; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors
D004375:Duffy Blood-Group System