Complicated nosocomial pneumonia due to Legionella pneumophila in an immunocompromised child.
An immunocompromised child developed necrotizing pneumonia with BAL cultures growing Legionella pneumophila resistant to treatment, including erythromycin and rifampicin. Ciprofloxacin and clarithromycin reversed the clinical course; their use as first-line drugs is justifiable and a high index of suspicion for the occurrence of legionellosis is warranted.
Trübel
Hubert K F
HK
Department of Pediatrics, Private University of Witten/Herdecke, Wuppertal, Germany. hubert.trubel@yale.edu
Meyer
Heinz G W
HG
Jahn
Bernhard
B
Knuf
Markus
M
Kamin
Wolfgang
W
Huth
Ralf G
RG
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D002939:Ciprofloxacin / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D003428:Cross Infection / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D016867:Immunocompromised Host; D016952:Legionella pneumophila / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D009748:Nutrition Disorders / Q000150:complications; D018410:Pneumonia, Bacterial / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D017291:Clarithromycin