Neuronal plasticity of interrelated cerebellar and cortical networks.
The comprehension of the cerebellar physiology is rapidly changing in particular because of the demonstration of the cerebellar importance on cognition. In the present paper, recent data on cerebro cerebellar interactions is reviewed, particularly focusing on cerebellar influences over the neurophysiology of primary motor and primary sensory cortices. The cerebellar role in implicit learning and in sensory data processing is analysed and discussed. It is proposed that the cerebellum could control cortical plastic changes by modulating cortical excitability in a discrete topographic manner and that this mechanism could induce the coupling between significant sensory inputs and definite motor outputs considered as the neurobiological substrate for implicit learning.
Molinari
M
M
Rehabilitation Hospital and Research Institute, Santa Lucia Foundation, Via Ardeatina 306, 00179, Rome, Italy. m.molinari@hsantalucia.it
Filippini
V
V
Leggio
M G
MG
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D004525:Efferent Pathways / Q000502:physiology; D006801:Humans; D007858:Learning; D009044:Motor Cortex / Q000502:physiology; D009473:Neuronal Plasticity; D013003:Somatosensory Cortex / Q000502:physiology