title: Effect of agitation intensity on the exo-biopolymer production and mycelial morphology in Cordyceps militaris.
abstract: OBJECTIVE
  The influence of agitation intensity on Cordyceps militaris morphology and exo-biopolymer production was investigated in a 5 litre stirred vessel using a six-blade Rushton turbine impeller.
  
  
  RESULTS
  The mycelial morphology of C. militaris was characterized by means of image analysis, which included mean diameter, circularity, roughness and compactness of the pellets. The morphological parameters of the pellets grown under different stirring conditions were significantly different, which correspondingly altered exo-biopolymer production yields.
  
  
  CONCLUSIONS
  The compactness of the pellets was found to be the most critical parameter affecting exo-biopolymer biosynthesis; more compact pellets were formed at 150 rev min(-1) with maximum exo-biopolymer production (15 g l(-1)).
  
  
  CONCLUSIONS
  The results of this study suggest that morphological change of pellets is a good indicator for identifying the cell activity for exo-biopolymer production.
authors.affiliation: Department of Biotechnology, Taegu University, Kyungsan, Kyungbuk, Korea.
authors.forename: J P
authors.initials: JP
authors.lastname: Park
authors.forename: Y M
authors.initials: YM
authors.lastname: Kim
authors.forename: S W
authors.initials: SW
authors.lastname: Kim
authors.forename: H J
authors.initials: HJ
authors.lastname: Hwang
authors.forename: Y J
authors.initials: YJ
authors.lastname: Cho
authors.forename: Y S
authors.initials: YS
authors.lastname: Lee
authors.forename: C H
authors.initials: CH
authors.lastname: Song
authors.forename: J W
authors.initials: JW
authors.lastname: Yun
mesh_terms: D001704:Biopolymers / Q000096:biosynthesis*; D019149:Bioreactors; D018929:Cell Culture Techniques / Q000379:methods; D005285:Fermentation; D006999:Hypocreales / Q000166:cytology / Q000378:metabolism
chemical_list: D001704:Biopolymers