title: Trigeminal neuropathy in dogs: a retrospective study of 29 cases (1991-2000).
abstract: The medical records of 29 dogs unable to close their mouths due to flaccid paralysis or paresis of the muscles innervated by the mandibular branch of the trigeminal nerve, were reviewed. Idiopathic trigeminal neuropathy was diagnosed in 26 dogs based on complete resolution of clinical signs and lack of any long-term neurological disease. Of these dogs, golden retrievers were overrepresented. No age, sex, or seasonal predispositions were identified. Trigeminal sensory innervation deficits were observed in 35% (9/26), facial nerve deficits were observed in 8% (2/26), and Horner's syndrome was observed in 8% (2/26) of dogs. Electromyographic examination of the muscles of mastication revealed abnormalities in seven of nine dogs. Results of cerebrospinal fluid analysis were abnormal in seven of eight dogs. Corticosteroid therapy did not affect the clinical course of the disease. Mean time to recovery was 22 days. Lymphosarcoma, Neospora caninum infection, and severe polyneuritis of unknown origin were diagnosed in three of 29 dogs at necropsy.
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, The University of Pennsylvania, Philadelphia 19104-6010, USA.
authors.forename: Philipp D
authors.initials: PD
authors.lastname: Mayhew
authors.forename: William W
authors.initials: WW
authors.lastname: Bush
authors.forename: Eric N
authors.initials: EN
authors.lastname: Glass
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D004285:Dogs; D004576:Electromyography / Q000662:veterinary; D005260:Female; D008297:Male; D010414:Pennsylvania / Q000453:epidemiology; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D020433:Trigeminal Nerve Diseases / Q000453:epidemiology / Q000662:veterinary*