Multibranched polyunsaturated and very-long-chain fatty acids of freshwater Israeli sponges.
Very-long-chain and multibranched polyunsaturated fatty acids of three freshwater sponges, Ephydatia syriaca, Nudospongilla sp., and Cortispongilla barroisi, were studied by silver TLC, GC-MS, UV, IR, HRMS, and NMR methods. One hundred and eighty-five conventional fatty acids were identified by GC-MS, out of which five were new multibranched polyunsaturated fatty acids. The freshwater sponges belonging to the family Spongillidae (class Demospongia) were shown to contain novel di-, tri-, and tetramethyl substituted dienoic, tetraenoic, and hexaenoic fatty acids. The compounds gave positive results in a brine shrimp toxicity assay.
Rezanka
Tomás
T
Institute of Microbiology, Vídenská 1083, 142 20, Prague, Czech Republic. rezanka@biomed.cas.cz
Dembitsky
Valery M
VM
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification*; D001156:Artemia / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D002855:Chromatography, Thin Layer; D005231:Fatty Acids, Unsaturated / Q000737:chemistry* / Q000302:isolation & purification*; D005618:Fresh Water; D008401:Gas Chromatography-Mass Spectrometry; D007557:Israel; D007597:Jordan; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D005231:Fatty Acids, Unsaturated