Pharmacotherapy in congestive heart failure: Vasopeptidase inhibition and its role in congestive heart failure.
Vasopeptidase inhibition--that is, the dual inhibition of ACE and neutral endopeptidase-reduces blood pressure in a potent manner. Preliminary studies suggest that vasopeptidase inhibition can also effectively treat congestive heart failure. Additional corroborating studies to support the use of vasopeptidase inhibition in heart failure are now underway. (c)2000 by CHF, Inc.
Sica
D A
DA
Division of Clinical Pharmacology and Hypertension, Medical College of Virginia of Virginia Commonwealth University, Richmond, VA 23298.