title: [A case of gastric cancer with multiple liver metastases responding to TS-1].
abstract: We report the case of a 58-year-old male with Stage IV gastric cancer accompanied by multiple liver metastases, which responded to chemotherapy using TS-1. The patient was treated with daily oral administration of 120 mg TS-1 for 4 weeks followed by 2 weeks rest as 1 cycle. After 4 cycles, most of the liver metastases had disappeared and serum CEA level was reduced from 140 to 53.9. The patient received chemotherapy at our outpatient clinic for 9 months during which time there was no regrowth after the first treatment. The current case suggests that TS-1 may have a potent therapeutic efficacy in cases of advanced gastric cancer.
authors.affiliation: Dept. of Surgery, Osaka Rosai Hospital.
authors.forename: Takashi
authors.initials: T
authors.lastname: Emoto
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Fujikawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Fujii
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Yoshioka
authors.forename: Eisaku
authors.initials: E
authors.lastname: Hamada
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Naka
authors.forename: Takamitu
authors.initials: T
authors.lastname: Komaki
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000188:drug therapy* / Q000556:secondary*; D000284:Administration, Oral; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D011725:Pyridines / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid