Synthesis and characterization of three new Cu(II)-dipeptide complexes.
Three new copper(II) complexes of stoichiometry [Cu(L-dipeptide)].nH(2)O, containing as ligands the dipeptides L-alanine-L-isoleucine, L-alanine-L-threonine and L-alanine-L-tyrosine were prepared. They were characterized by single crystal X-ray diffractometry, and electronic and infrared spectroscopy. In all cases, the Cu(II) cation has essentially the same elongated square pyramidal coordination, being equatorially cis coordinated by a N(2)O(2) arrangement of ligand atoms and axially by a carbonyl oxygen atom. The compounds show rather similar polymeric structures which resemble those recently reported for the [Cu(ala-val)] and [Cu(ala-phe)] complexes. The electronic and infrared spectra are briefly discussed on the basis of the structural peculiarities of the complexes. Superoxide dismutase (SOD)-like activity was also tested for the compounds.
Facchin
Gianella
G
Cátedra de Química Inorgánica, Facultad de Química, Universidad de la República, Montevideo, Uruguay.
Torre
María H
MH
Kremer
Eduardo
E
Piro
Oscar E
OE
Castellano
Eduardo E
EE
Baran
Enrique J
EJ
D000818:Animals; D002417:Cattle; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004151:Dipeptides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000378:metabolism; D004912:Erythrocytes; D008958:Models, Molecular; D008968:Molecular Conformation; D013055:Spectrophotometry, Infrared; D013482:Superoxide Dismutase / Q000378:metabolism
D004151:Dipeptides; D003300:Copper; D013482:Superoxide Dismutase