title: Clinical presentation of community-acquired Chlamydia pneumoniae pneumonia in adults.
abstract: OBJECTIVE
  To investigate the clinical presentation of community-acquired Chlamydia pneumoniae pneumonia in adults.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Kawasaki Medical School Hospital, Kawasaki Medical School Kawasaki Hospital, and Kurashiki Daiichi Hospital in Japan.
  
  
  METHODS
  Forty patients with community-acquired pneumonia with C pneumoniae as the only pathogen identified admitted to three hospitals between April 1996 and March 2001 and their clinical presentations were compared to patients with Streptococcus pneumoniae and Mycoplasma pneumoniae pneumonia.
  
  
  METHODS
  The diagnosis of C pneumoniae infection was based on isolation and serologic testing of antibodies by the microimmunofluorescence test.
  
  
  RESULTS
  The clinical presentations, except for shortness of breath, were similar for the three major etiologic agents. The mean temperature of C pneumoniae patients on hospital admission was 37.9 degrees C, which was lower than that of patients with S pneumoniae and M pneumoniae. The mean WBC count on hospital admission was lower in the patients with C pneumoniae (mean, 9,100/microL) than in those with S pneumoniae pneumonia but higher than in those with M pneumoniae pneumonia. No patients required respiratory support or admission to an ICU, and no deaths occurred among the C pneumoniae pneumonia patients.
  
  
  CONCLUSIONS
  Our results indicate that C pneumoniae pneumonia as a single etiologic agent is mild and that the underlying conditions and clinical symptoms closely resemble those of S pneumoniae pneumonia. However, the physical examinations, laboratory findings, and prognostic factors of the C pneumoniae patients resembled those of patients with M pneumoniae pneumonia.
authors.affiliation: Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Okayama, Japan. nao@med.kawasaki-m.ac.jp
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Miyashita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukano
authors.forename: Niro
authors.initials: N
authors.lastname: Okimoto
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hara
authors.forename: Koichiro
authors.initials: K
authors.lastname: Yoshida
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Niki
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Matsushima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D023521:Chlamydophila Infections / Q000175:diagnosis* / Q000382:microbiology; D016993:Chlamydophila pneumoniae; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies