title: Effect of aerobic and resistance exercise on central hemodynamic responses in severe chronic heart failure.
abstract: Exercise is now considered an important component of management in chronic heart failure (CHF), but little is known about central hemodynamic changes that occur during different exercise modalities in these patients. Seventeen patients (ejection fraction 25 +/- 2%) undertook brachial artery and right heart catheterization and oxygen consumption assessment at rest, during submaximal and peak cycling (Cyc), and during submaximal upper and lower limb resistance exercise. Cardiac output (CO) increased relative to baseline during peak Cyc (P < 0.05) but did not change during submaximal Cyc or upper or lower limb exercise. Heart rate (HR) was lowest during upper limb exercise and progressively increased during lower limb exercise, submaximal Cyc, and peak Cyc, with significant differences between each of these (P < 0.01). Conversely, stroke volume (SV) decreased during submaximal Cyc and lower limb exercise and was lower during peak and submaximal Cyc and lower limb exercise than during upper limb exercise (P < 0.05). CHF patients are dependent on increases in HR to increase CO during exercise when SV may decline. Resistance exercise, performed at appropriate intensity, induces a similar hemodynamic burden to aerobic exercise in patients with CHF.
authors.affiliation: Department of Human Movement and Exercise Science, The University of Western Australia, Crawley 6009, Australia.
authors.forename: Craig
authors.initials: C
authors.lastname: Cheetham
authors.forename: Daniel
authors.initials: D
authors.lastname: Green
authors.forename: Julie
authors.initials: J
authors.lastname: Collis
authors.forename: Lawrence
authors.initials: L
authors.lastname: Dembo
authors.forename: Gerard
authors.initials: G
authors.lastname: O'Driscoll
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D001132:Arm / Q000502:physiology; D001642:Bicycling; D006328:Cardiac Catheterization; D002908:Chronic Disease; D015444:Exercise / Q000502:physiology*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy / Q000503:physiopathology*; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007866:Leg / Q000502:physiology; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D013318:Stroke Volume / Q000502:physiology; D014891:Weight Lifting / Q000502:physiology
chemical_list: D000319:Adrenergic beta-Antagonists