[Cardiovascular physiology: recent findings].
The practice, research and teaching of biology have changed considerably over the last few years, largely due to the sequencing of all of the human genome. These changes are of interest to both the researcher and clinician, the physician and surgeon. They involve the tools, genetic transfers and transgenic technology, global methods of analysis of genetic expressions directly generated by the genome programme and computerisation. Several major concepts have evolved: transgenic physiology or reverse physiology which allows study of all functions, especially cardiac, and their determining factors; functional and physiological genomics which allow the study of all changes of genic expression, in cardiac failure for example; physiological convergences in genetics which underline the increasing importance of the physiologist in genetics; pharmacogenetics finally, the genetics which allow better choice of treatment for each individual.
Swynghedauw
B
B
U127-INSERM, hôpital Lariboisière, Paris.
D002320:Cardiovascular Physiological Phenomena; D005786:Gene Expression Regulation; D015894:Genome, Human; D006321:Heart / Q000502:physiology; D006801:Humans; D012984:Software
Physiologie cardiovasculaire: les nouvelles donnes.