Gene structure identification with MyGV using cDNA evidence and protein homologs to improve ab initio predictions.
MyGV is an application to visualize (potentially genome-scale) gene structure annotation and prediction. The output of any external gene prediction program can be easily converted to a generalized format for input into MyGV. The application displays all input simultaneously in graphical representation, with a toggle option for a text-based view. Zooming capabilities allow detailed comparisons for specific genome locations. The tool is particularly helpful for refinement of ab initio predicted gene structures by spliced alignment with cDNA or protein homologs.


BACKGROUND
The program was written in Java and is freely available to non-commercial users by electronic download from http://bioinformatics.iastate.edu/bioinformatics2go/MyGV.
Zhu
Wei
W
Department of Zoology and Genetics, Iowa State University, Ames, IA 50011, USA.
Brendel
Volker
V
D000818:Animals; D001483:Base Sequence; D003626:Data Display; D003628:Database Management Systems; D030541:Databases, Genetic; D030561:Databases, Nucleic Acid; D004330:Drosophila / Q000235:genetics; D016678:Genome; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA / Q000379:methods*; D017385:Sequence Homology; D012984:Software; D014584:User-Computer Interface