Expression of alpha tubulin during the dimorphic transition of Paracoccidioides brasiliensis.
In this study we analyzed the expression of (alpha-tubulin during the dimorphic transition of the human-pathogenic fungus Paracoccidioides brasiliensis. The alpha-tubulin from P. brasiliensis was recognized by a commercially available anti-tubulin antibody and was developmentally regulated during the dimorphic form transition. We detected at least two alpha-tubulin isoforms in the mycelial state and only one isoform in the yeast forms. This finding suggests specific roles for the alpha-tubulin isoforms in P. brasiliensis's yeast and mycelial forms.
Silva
W P
WP
Laboratório de Biologia Molecular, ICB II, Universidade Federal de Goiás, Goiânia, Brazil.
Soares
R B
RB
Jesuino
R S
RS
Izacc
S M
SM
Felipe
M S
MS
Soares
C M
CM
D025282:Mycelium / Q000737:chemistry; D010228:Paracoccidioides / Q000737:chemistry* / Q000254:growth & development / Q000378:metabolism; D020033:Protein Isoforms; D014404:Tubulin / Q000032:analysis* / Q000096:biosynthesis
D020033:Protein Isoforms; D014404:Tubulin