[The role of monocytes stimulated with LPS on CD69 expression in T lymphocytes of patients with non-atopic asthma].
CD69 molecule is the earliest antigen of T lymphocytes activation. We have studied the ex-pression of CD69 on LPS-stimulated T cells in nonatopic bronchial asthma. We have found that CD69 expression on freshly isolated peripheral blood T cells in nonatopic asthma patients was increased compare to control group (4.74 +/- 1.55/3.05 +/- 1.31) and the difference was statistically significant (p < 0.01). Monocytes added to nonstimulated T cell cultures increased 3-4 times the expression of CD69 and about 10-times in LPS-stimulated T lymphocytes.
Moniuszko
Tadeusz
T
Klinika Alergologii i Chorób Wewnetrznych Akademii Medycznej w Białymstoku.
Rutkowski
Ryszard
R
Tatarczuk-Krawiel
Anetta
A
Stasiak-Barmuta
Anna
A
Siergiejko
Zenon
Z
D015703:Antigens, CD / Q000276:immunology*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology*; D001249:Asthma / Q000276:immunology*; D005260:Female; D006801:Humans; D037181:Lectins, C-Type; D008070:Lipopolysaccharides / Q000276:immunology; D008213:Lymphocyte Activation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D000099192:CD69 Antigens
D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D037181:Lectins, C-Type; D008070:Lipopolysaccharides; D000099192:CD69 Antigens
Wpływ monocytów stymulowanych LPS na ekspresje CD69 na limfocytach T u chorych na astme nieatopowa.