RNAi targeting an animal virus: news from the front.
Although many eukaryotic organisms exhibit RNA interference, its role as an antiviral pathway is established only for plants. A recent paper demonstrates that it also acts in animals, and reveals a viral suppressor of this process.
Lindenbach
Brett D
BD
Center for the Study of Hepatitis C, Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10021, USA.
Rice
Charles M
CM
D000818:Animals; D004331:Drosophila melanogaster; D016153:Genes, Suppressor / Q000502:physiology*; D012313:RNA; D016372:RNA, Antisense / Q000502:physiology*; D034741:RNA, Small Interfering; D014780:Viruses / Q000235:genetics*; D019892:eIF-2 Kinase / Q000235:genetics / Q000378:metabolism
D016372:RNA, Antisense; D034741:RNA, Small Interfering; D012313:RNA; D019892:eIF-2 Kinase