Generalized lichen nitidus successfully treated with an antituberculous agent.
We describe a Japanese girl with generalized lichen nitidus. She had been exposed to Mycobacterium tuberculosis at 6 years of age via her teacher. At 8 years of age, she developed severe contact dermatitis on sun-exposed areas after contact with Japanese lacquer trees. Shortly after, numerous tiny, shiny, flesh-coloured papules developed over the upper part of her body. At 10 years of age, she was exposed to a school outbreak of M. tuberculosis. Her eruption showed no response to topical corticosteroids or oral tranilast, but most of the papules completely disappeared after she had received oral isoniazid for 6 months.
Kubota
Y
Y
Department of Dermatology, School of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.
Kiryu
H
H
Nakayama
J
J
D000995:Antitubercular Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000209:etiology; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000209:etiology; D007538:Isoniazid / Q000627:therapeutic use*; D017513:Lichen Nitidus / Q000188:drug therapy* / Q000473:pathology
D000995:Antitubercular Agents; D007538:Isoniazid