Selenium in the neonate.
Selenium is a trace element of tremendous importance in human health. It is a constituent of the antioxidant enzyme. Glutathione peroxidase and therefore is vital to antioxidant defense. Several diseases of the neonate have been shown to be caused at least in part by oxygen free radicals. These include bronchopulmonary dysplasia retinopathy of prematurity necrotising enterocolitis patient ductus arteriosus and neuronal injury of hypoxic ischemic encephalopathy. Good selenium nutrition is therefore of key importance to antioxidant defense in the neonate. The communique reviews the important role that selenium might play in neonatal health & disease.
Gathwala
Geeta
G
Department of Pediatrics, Pt. Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana. g_gathwala@sify.com
Yadav
O P
OP
D000975:Antioxidants / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology* / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D012643:Selenium / Q000172:deficiency* / Q000378:metabolism
D000975:Antioxidants; D017382:Reactive Oxygen Species; D005979:Glutathione Peroxidase; D012643:Selenium