Pioneering work in vertebrate neural development.
Control of directional axon growth is fundamental to correct wiring in the nervous system, and glia are thought to play an important role. New work in the zebrafish lateral line shows that glia are not required for axonal pathfinding but are required for normal mature nerve organization.
Stemple
Derek L
DL
Division of Developmental Biology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom.
D000818:Animals; D030801:Animals, Genetically Modified; D001369:Axons / Q000502:physiology; D019521:Body Patterning; D002465:Cell Movement; D009154:Mutation; D009414:Nerve Growth Factors / Q000378:metabolism; D009420:Nervous System / Q000196:embryology*; D009432:Neural Crest / Q000166:cytology; D009457:Neuroglia / Q000502:physiology; D014714:Vertebrates / Q000254:growth & development*; D015027:Zebrafish / Q000196:embryology / Q000235:genetics
D009414:Nerve Growth Factors