[Hydrodynamic and biochemical effects of hypothermic perfusion of isolated kidney according to the type of pump].
OBJECTIVE
To study on isolated kidney perfusions by means of a self-designed computer-controlled organ perfusion system the hydrodynamic and biochemical effects of two types of pumps: a self-designed vacuum powered tubular pump and a classical roller pump.


METHODS
Experimental study performed on 12 right mini-pig kidneys. After transperitoneal bilateral nephrectomy, organs are perfused with Eurocollins solution in a randomised manner with one type of pump. The system records continuously perfusion pressure, flow and renal resistance.


RESULTS
Medium renal vascular resistance was significantly lower in vacuum powered tubular pump perfusions. LDH level in the solution showed correlation with perfusion flow.


CONCLUSIONS
Vacuum powered tubular pump increases renal flow and lowers renal vascular resistance significantly in comparison to roller pump. LDH level in the solution is related to good-quality hydrodynamic perfusion parameter values.
Lledó García
E
E
Servicio de Urología, Fundación Hospital Alcorcón, Alcorcón, Madrid.
Hernández Fernández
C
C
Llorente Abarca
C
C
del Cañizo López
J F
JF
D000818:Animals; D007036:Hypothermia, Induced; D007668:Kidney / Q000502:physiology*; D010477:Perfusion / Q000295:instrumentation*; D013556:Swine, Miniature
Efectos hidrodinámicos y bioquímicos de la perfusión hipotérmica de riñón aislado según el tipo de bomba utilizada.