title: Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.
abstract: Recent technological breakthroughs allowing for large-scale analysis of gene transcripts and large-scale monitoring of the immune response with protein chips are revealing new participants in the pathogenesis of multiple sclerosis. Some of these participants may be useful targets for therapy.
authors.affiliation: Department of Neurology and Neurological Sciences, Stanford University School of Medicine, California 94305, USA. steinman@stanford.edu
authors.forename: Lawrence
authors.initials: L
authors.lastname: Steinman
authors.forename: Roland
authors.initials: R
authors.lastname: Martin
authors.forename: Claude
authors.initials: C
authors.lastname: Bernard
authors.forename: Paul
authors.initials: P
authors.lastname: Conlon
authors.forename: Jorge R
authors.initials: JR
authors.lastname: Oksenberg
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D005786:Gene Expression Regulation / Q000276:immunology; D006801:Humans; D018836:Inflammation Mediators / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D009103:Multiple Sclerosis / Q000235:genetics* / Q000276:immunology* / Q000628:therapy; D009186:Myelin Sheath / Q000276:immunology* / Q000473:pathology
chemical_list: D018836:Inflammation Mediators