title: Submillimeter-wave phonon modes in DNA macromolecules.
abstract: A detailed investigation of phonon modes in DNA macromolecules is presented. This work presents experimental evidence to confirm the presence of multiple dielectric resonances in the submillimeter-wave spectra (i.e., approximately 0.01-10 THz) obtained from DNA samples. These long-wave (i.e., approximately 1-30 cm(-1)) absorption features are shown to be intrinsic properties of the particular DNA sequence under study. Most importantly, a direct comparison of spectra between different DNA samples reveals a large number of modes and a reasonable level of sequence-specific uniqueness. This work establishes the initial foundation for the future use of submillimeter-wave spectroscopy in the identification and characterization of DNA macromolecules.
authors.affiliation: U.S. Army Research Laboratory, Army Research Office, Research Triangle Park, North Carolina 27709, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Woolard
authors.forename: T R
authors.initials: TR
authors.lastname: Globus
authors.forename: B L
authors.initials: BL
authors.lastname: Gelmont
authors.forename: M
authors.initials: M
authors.lastname: Bykhovskaia
authors.forename: A C
authors.initials: AC
authors.lastname: Samuels
authors.forename: D
authors.initials: D
authors.lastname: Cookmeyer
authors.forename: J L
authors.initials: JL
authors.lastname: Hesler
authors.forename: T W
authors.initials: TW
authors.lastname: Crowe
authors.forename: J O
authors.initials: JO
authors.lastname: Jensen
authors.forename: J L
authors.initials: JL
authors.lastname: Jensen
authors.forename: W R
authors.initials: WR
authors.lastname: Loerop
mesh_terms: D001703:Biophysics / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D008962:Models, Theoretical; D009690:Nucleic Acid Conformation; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D004247:DNA