Familial Mediterranean fever in 2 Japanese families.
We describe 3 Japanese patients in 2 families with familial Mediterranean fever (FMF) as determined by gene analysis. FMF is an ethnically related, genetic disease, occurring commonly in some Mediterranean populations. The FMF gene (MEFV) mutation found in our patients is M694I. The patients may be remote from East Asian extraction.
Shinozaki
Koji
K
Department of Pediatrics, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.
Agematsu
Kazunaga
K
Yasui
Kozo
K
Nagumo
Haruo
H
Naitoh
Hajime
H
Naganuma
Kuniaki
K
Komiyama
Atsushi
A
D000293:Adolescent; D000328:Adult; D004252:DNA Mutational Analysis; D010505:Familial Mediterranean Fever / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D007564:Japan; D020125:Mutation, Missense; D010375:Pedigree; D017354:Point Mutation