title: [Hormonal replacement therapy in Spain].
abstract: BACKGROUND
  The consumption of hormonal replacement therapy (HRT) in Spain is not known. Therefore, we have conducted a study to know the mean features of that consumption and to find out the prevalence of use among women older than 40.
  
  
  METHODS
  To know the consumption, we have used the information contained in ECOM database from the Ministry of Health regarding medicines sold to the Spanish Health System. Also, data gathered by the General Practitioner Sentinel Network of Castilla y León had been used. The data of consumption are presented in daily defined dose per 1000 women more than 40 years (DHD); prevalence of use per year and for ages was also estimated.
  
  
  RESULTS
  The HRT consumption in Spain throughout the National Health System was 6,94 DHD in 1989 and 39.92 DHD in 1999. The percentage of women using this therapy was 0.7% in 1989 and 3,4 in 1999; the group 50-54 years had the highest prevalence of use, 10,84% (IC 95%, 10.66-11.01).
  
  
  CONCLUSIONS
  The release into the market of those transdermal forms of HRT facilitated an increase in the consumption. Nonetheless, the proportion of postmenopausal women on HRT in Spain is lower than that of the other countries from the European Union. The proportion of women treated with estrogens and progestins is also small compared with current recommendations.
authors.affiliation: Instituto de Farmacoepidemiología, Facultad de Medicina, Universidad de Valladolid, Spain.
authors.forename: Mikhail
authors.initials: M
authors.lastname: Benet Rodríguez
authors.forename: Alfonso
authors.initials: A
authors.lastname: Carvajal García-Pando
authors.forename: Javier
authors.initials: J
authors.lastname: García Del Pozo
authors.forename: Ana
authors.initials: A
authors.lastname: Alvarez Requejo
authors.forename: Tomás
authors.initials: T
authors.lastname: Vega Alonso
mesh_terms: D000328:Adult; D015914:Estrogen Replacement Therapy / Q000706:statistics & numerical data*; D004967:Estrogens; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000502:physiology*; D015995:Prevalence; D013030:Spain
chemical_list: D004967:Estrogens
vernacular_title: Tratamiento hormonal sustitutivo en España. Un estudio de utilización.