title: Egyptian propolis: 2. Chemical composition, antiviral and antimicrobial activities of East Nile Delta propolis.
abstract: Three propolis samples from East Nile Delta, Egypt were collected. Propolis samples were investigated by GC/MS,103 compounds were identified, 20 being new for propolis. Dakahlia propolis was a typical poplar propolis but it contained two new caffeate esters and two new triterpenoids. Ismailia propolis was characterized by the presence of new triterpenic acid methyl esters and it did not contain any aromatic acids, esters and flavonoids. Sharkia propolis was characterized by the presence of caffeate esters only, some di- and triterpenoids. The antiviral (Infectious Bursal Disease Virus and Reo-Virus) and antimicrobial (Staphylococcus aureus; Escherichia coli and Candida albicans) activities of propolis samples were investigated. Dakahlia propolis showed the highest antiviral activity against Infectious Bursal Disease Virus (IBDV) and the highest antibacterial activity against Escherichia coli and the highest antifungal activity against Candida albicans. While Ismailia propolis had the highest antiviral activity against Reo-virus. Sharkia propolis showed the highest antibacterial activity against Staphylococcus aureus and moderate antiviral activity against infectious bursal disease virus and reovirus.
authors.affiliation: Department of Chemistry of Natural Products, National Research Center, Dokki, Giza, Egypt.
authors.forename: Faten K
authors.initials: FK
authors.lastname: Abd El Hady
authors.forename: Ahmed G
authors.initials: AG
authors.lastname: Hegazi
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D002241:Carbohydrates / Q000737:chemistry; D002642:Chick Embryo; D004224:Diterpenes / Q000737:chemistry; D004534:Egypt; D004926:Escherichia coli / Q000187:drug effects; D004952:Esters / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D007243:Infectious bursal disease virus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D011429:Propolis / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D014315:Triterpenes / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000998:Antiviral Agents; D002241:Carbohydrates; D004224:Diterpenes; D004952:Esters; D005419:Flavonoids; D014315:Triterpenes; D011429:Propolis