title: Reversal of Phen-Fen associated valvular regurgitation documented by serial echocardiography.
abstract: We report a case of anorexigen-associated moderate to severe aortic and mitral regurgitation in which the regression of lesions was marked and well documented over more than 2 years. The stability of our patient, as well as the degree of regression of regurgitation documented in our patient, and others, suggests it is prudent both to observe such patients and to avoid operation until such observation has been carried out.
authors.affiliation: Department of Medicine, Stanford University School of Medicine, CA, USA.
authors.forename: Randall
authors.initials: R
authors.lastname: Vagelos
authors.forename: Michael
authors.initials: M
authors.lastname: Jacobs
authors.forename: Richard L
authors.initials: RL
authors.lastname: Popp
authors.forename: David
authors.initials: D
authors.lastname: Liang
mesh_terms: D001067:Appetite Depressants / Q000009:adverse effects*; D004452:Echocardiography; D005260:Female; D005277:Fenfluramine / Q000009:adverse effects*; D006349:Heart Valve Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D010645:Phentermine / Q000009:adverse effects*; D020127:Recovery of Function
chemical_list: D001067:Appetite Depressants; D005277:Fenfluramine; D010645:Phentermine