title: Comparison of PCDD/F and coplanar PCB concentrations in Japanese human adipose tissue collected in 1970-1971, 1994-1996 and 2000.
abstract: Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and coplanar biphenyls (Co-PCBs) were determined in Japanese human adipose tissues. Temporal trends were assessed by comparing data collected during 1970-1971, 1994-1996 and 2000. Mean TEQ levels of PCDD/Fs in human adipose tissue showed a significant decrease from 31.6 +/- 9.2 pg-TEQ/g fat wt in 1970-1971 to 11.9 +/- 7.4 pg-TEQ/g fat wt in 2000, and coplanar PCBs decreased from 35.4 +/- 21.9 pg-TEQ/g fat wt in 1970-1971 to 15.3 +/- 8.2 pg-TEQ/g fat wt in 2000. However, some PCB congener concentrations did not change during this time. A comparison of data using the latest PCB-TEQ showed no significant changes. Therefore, research on source characterization and monitoring of short-term temporal trends on these compounds should be carried out continuously.
authors.affiliation: National Institute for Environmental Studies, Ibaraki, Japan. choi.jae.won@nies.go.jp
authors.forename: Jae-Won
authors.initials: JW
authors.lastname: Choi
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Miyabara
authors.forename: Shunji
authors.initials: S
authors.lastname: Hashimoto
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Morita
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry*; D001572:Benzofurans / Q000032:analysis / Q000493:pharmacokinetics*; D002102:Cadaver; D000072338:Dibenzofurans, Polychlorinated; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000032:analysis / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000493:pharmacokinetics*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis / Q000493:pharmacokinetics*; D012189:Retrospective Studies; D012989:Soil Pollutants / Q000032:analysis / Q000493:pharmacokinetics*; D014018:Tissue Distribution
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D004785:Environmental Pollutants; D000072317:Polychlorinated Dibenzodioxins; D012989:Soil Pollutants; D011078:Polychlorinated Biphenyls