title: Geometric reconstruction for computational mesh generation of arterial bifurcations from CT angiography.
abstract: A methodology for patient-specific model reconstruction and computational mesh generation of arterial bifurcations from angio-CT scans is presented. Three-dimensional models were reconstructed with a level set technique, analyzed with a skeletoning algorithm and automatically decomposed into branches. Cooper scheme was then employed to generate high quality hexahedral mesh. We successfully applied our technique to the carotid bifurcations of two patients affected by severe atherosclerotic plaques. The proposed technique is fast, accurate and reproducible, and can be a useful tool for the evaluation of arterial fluid dynamics within conventional computed tomography investigations.
authors.affiliation: Department of Bioengineering, Clinical Research Center for Rare Diseases Aldo e Cele Daccò, Mario Negri Institute for Pharmacological Research, Villa Camozzi, 24020 Ranica, BG, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Antiga
authors.forename: Bogdan
authors.initials: B
authors.lastname: Ene-Iordache
authors.forename: Lionello
authors.initials: L
authors.lastname: Caverni
authors.forename: Gian Paolo
authors.initials: GP
authors.lastname: Cornalba
authors.forename: Andrea
authors.initials: A
authors.lastname: Remuzzi
mesh_terms: D000368:Aged; D000465:Algorithms; D000792:Angiography / Q000379:methods*; D001158:Arteries / Q000033:anatomy & histology*; D001161:Arteriosclerosis / Q000000981:diagnostic imaging; D016893:Carotid Stenosis / Q000000981:diagnostic imaging; D003287:Contrast Media; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media