GeneNet database: description and modeling of gene networks.
Almost all cellular processes in an organism are controlled by gene networks. Here we report on the analysis of gene networks functioning using two associated methods - data accumulation in GeneNet system and generalized chemical kinetic method for mathematical simulation of gene network functional dynamics. The technology of the usage of these methods is shown on the example of the gene network of macrophage activation.
Kolchanov
Nikolay A
NA
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia.
Nedosekina
Eugenia A
EA
Ananko
Elena A
EA
Likhoshvai
Vitaly A
VA
Podkolodny
Nikolay L
NL
Ratushny
Alexander V
AV
Stepanenko
Irina L
IL
Podkolodnaya
Olga A
OA
Ignatieva
Elena V
EV
Matushkin
Yury G
YG
D000465:Algorithms; D019295:Computational Biology; D003198:Computer Simulation; D004247:DNA / Q000378:metabolism*; D030541:Databases, Genetic; D005786:Gene Expression Regulation; D005796:Genes; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D008213:Lymphocyte Activation / Q000502:physiology; D008264:Macrophages / Q000502:physiology; D011506:Proteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D014584:User-Computer Interface
D011506:Proteins; D012313:RNA; D004247:DNA