Beyond the proteome: non-coding regulatory RNAs.
A variety of RNA molecules have been found over the last 20 years to have a remarkable range of functions beyond the well-known roles of messenger, ribosomal and transfer RNAs. Here, we present a general categorization of all non-coding RNAs and briefly discuss the ones that affect transcription, translation and protein function.
Szymański
Maciej
M
Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14, 61-704 Poznań, Poland.
Barciszewski
Jan
J
D000818:Animals; D004303:Dosage Compensation, Genetic; D016678:Genome; D018392:Genomic Imprinting / Q000235:genetics; D006801:Humans; D014176:Protein Biosynthesis / Q000235:genetics; D021382:Protein Sorting Signals / Q000235:genetics; D011506:Proteins / Q000502:physiology; D020543:Proteome / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D022661:RNA, Untranslated / Q000235:genetics*; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*; D017423:Sequence Analysis, RNA / Q000379:methods; D015533:Transcriptional Activation / Q000235:genetics
D021382:Protein Sorting Signals; D011506:Proteins; D020543:Proteome; D012333:RNA, Messenger; D022661:RNA, Untranslated