title: [Fitz-Hugh-Curtis syndrome: 2 patients with perihepatitis and sepsis].
abstract: Two women aged 53 and 22 years presented with abdominal pain and signs of sepsis with metabolic acidosis. The first patient had ecchymoses all over her body, the second patient had an enlarged left kidney with wedge-shaped hypo-intense areas on the CT scan. The clinical condition of both women deteriorated. On laparoscopy perihepatitis with fibrin wires ('violin strings') was seen, pathognomonic for Fitz-Hugh-Curtis syndrome. Upon appropriate antibiotic treatment, both patients fully recovered. Although it is common belief that Fitz-Hugh-Curtis syndrome is caused by local spread from the fallopian tubes into the peritoneal cavity, these presentations suggest a haematogenous spread of Neisseria gonorrhoeae as well as Chlamydia trachomatis in the first case, and C. trachomatis in the second case.
authors.affiliation: Diakonessenhuis Utrecht, afd. Microbiologie, Bosboomstraat 1, 3582 KE Utrecht. jkaan@diakhuis.nl
authors.forename: J A
authors.initials: JA
authors.lastname: Kaan
authors.forename: J
authors.initials: J
authors.lastname: Branger
authors.forename: J M A
authors.initials: JM
authors.lastname: van Ampting
authors.forename: P
authors.initials: P
authors.lastname: Speelman
mesh_terms: D000005:Abdomen; D015746:Abdominal Pain; D000138:Acidosis; D000328:Adult; D002690:Chlamydia Infections / Q000150:complications* / Q000188:drug therapy; D002692:Chlamydia trachomatis; D004438:Ecchymosis; D005260:Female; D006069:Gonorrhea / Q000150:complications* / Q000188:drug therapy; D006505:Hepatitis / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009344:Neisseria gonorrhoeae; D018805:Sepsis; D013577:Syndrome
vernacular_title: Het syndroom van Fitz-Hugh-Curtis: 2 patiëntes met perihepatitis en ook sepsis.