title: Predictors of clinical outcome following NIR stent implantation for coronary artery disease: analysis of the results of the First International New Intravascular Rigid-Flex Endovascular Stent Study (FINESS trial).
abstract: BACKGROUND
  Patient and procedural characteristics associated with major adverse cardiac events following balloon angioplasty have been identified. Factors predictive of angiographic restenosis following coronary stent implantation have been reported, although patient variables associated with adverse clinical outcome are not well defined. HYPOTHESIS AND METHODS: To identify predictors of adverse clinical outcome following NIR stent implantation, clinical and angiographic characteristics of patients enrolled in the FINESS Trial were subjected to stepwise logistic regression analysis. From December 1995 through March 1996, NIR stent implantation was attempted in 255 patients (341 lesions) enrolled prospectively in a multicenter registry with broad entry criteria.
  
  
  RESULTS
  On stepwise logistic regression analysis, the presence of multivessel disease, diabetes, and the total length of the stented segment were predictive of major adverse cardiac events during 6-month follow-up. For every 1 mm increase in stent length, the risk for the combined end point of death or myocardial infarction increased by 3%. Lesion length was not predictive of clinical events on multivariate analysis.
  
  
  CONCLUSIONS
  Our data raise the possibility that an attempt to use shorter stents to cover significant stenoses, but not adjacent areas of visible narrowing, may improve outcome.
authors.affiliation: Heart and Vascular Diagnostic Clinic, Livingston, Texas 77351-9998, USA. Jsfeld@LCC.net
authors.forename: Steven
authors.initials: S
authors.lastname: Feld
authors.forename: Yaron
authors.initials: Y
authors.lastname: Almagor
authors.forename: William K
authors.initials: WK
authors.lastname: Vaughn
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Serruys
mesh_terms: D003324:Coronary Artery Disease / Q000628:therapy*; D006801:Humans; D015999:Multivariate Analysis; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome