title: [Uterine rupture on unscarred uterus following labor induction for 2(nd) trimester termination of pregnancy with oral misoprostol: conservative management].
abstract: Uterine rupture occurred at 25 weeks amenorrhea during pregnancy termination by misoprostol for fetal polykystosis. Rupture occurred on an unscared uterus after administration of significant accumulated doses of oral misoprostol (1400 g). The patient was managed conservatively and carried a subsequent pregnancy six months after the intervention. This accident occurs in 0.1% to 1% of the cases (0.59% in our experience) and only rare cases have been attributed to the use of misprostol. Clinicians should be particularly careful in patients with prior cesarean section or a weakened uterus.
authors.affiliation: Fédération de Gynécologie-Obstétrique, CHU Toulouse-La Grave, place Lange, 31052 Toulouse, France.
authors.forename: B
authors.initials: B
authors.lastname: Letourneur
authors.forename: O
authors.initials: O
authors.lastname: Parant
authors.forename: V
authors.initials: V
authors.lastname: Tofani
authors.forename: A
authors.initials: A
authors.lastname: Berrebi
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000009:adverse effects*; D000028:Abortion, Induced / Q000009:adverse effects*; D000328:Adult; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000009:adverse effects*; D016595:Misoprostol / Q000008:administration & dosage / Q000009:adverse effects*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D014597:Uterine Rupture / Q000209:etiology* / Q000628:therapy*
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D016595:Misoprostol
vernacular_title: Rupture utérine sur utérus sain au cours d'une interruption médicale de grossesse du 2(e) trimestre par misoprostol.