The effect of adnexal surgery on the ovarian response to stimulation in in vitro fertilization.
OBJECTIVE
The effect of adnexal surgery on ovarian function is a controversial issue of high clinical significance. The purpose of this study was to assess the effect of adnexal surgery on ovarian function.


METHODS
All patients who underwent adnexal surgery in our department during an 8-year period (all records were obtained from the hospital database between January 1991 and December 1998) were cross-matched with our in vitro fertilization (IVF) database. We compared the baseline hormonal levels and the patients' response to IVF stimulation (assessed by the total amount of gonadotropins, maximal estradiol (E2) levels, number of retrieved and fertilized oocytes).


RESULTS
Sixty-four consecutive patients who underwent adnexal surgery were compared with 68 matched controls. Neither of the analyzed parameters were affected by the tubal surgery.


CONCLUSIONS
We conclude from our study adnexal surgery is not detrimental to ovarian function.
Shulman
Adrian
A
In Vitro Fertilization Unit, Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Aviv University, 52621, Tel Hashomer, Israel. adrian@netvision.net.il
Marom
Hadar
H
Oelsner
GabI
G
Horowitz
Ariel
A
Ben-Nun
Isaac
I
Mashiach
Shlomo
S
Dor
Jehoshua
J
D000290:Adnexa Uteri / Q000601:surgery*; D000328:Adult; D016022:Case-Control Studies; D004624:Embryo Transfer / Q000706:statistics & numerical data; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy; D010535:Laparoscopy / Q000009:adverse effects; D007813:Laparotomy / Q000009:adverse effects; D009865:Oocytes / Q000502:physiology; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D012489:Salpingostomy / Q000009:adverse effects
D004958:Estradiol