title: The effect of tilmicosin on cardiac superoxide dismutase and glutathione peroxidase activities.
abstract: In this study, the effect of tilmicosin on cardiac superoxide dismutase and glutathione peroxidase activities was investigated. Forty male BALB/c mice were used as material. Ten mice served as a control group, and 30 mice were injected with tilmicosin (25 mg/kg body weight, subcutaneously, with a single injection). After drug administration, they were monitored for 3 days. Tilmicosin caused decreases in cardiac superoxide dismutase and glutathione peroxidase activities.
authors.affiliation: Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Yazar
authors.forename: V
authors.initials: V
authors.lastname: Altunok
authors.forename: M
authors.initials: M
authors.lastname: Elmas
authors.forename: B
authors.initials: B
authors.lastname: Traş
authors.forename: A L
authors.initials: AL
authors.lastname: Baş
authors.forename: V
authors.initials: V
authors.lastname: Ozdemir
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D005979:Glutathione Peroxidase / Q000187:drug effects / Q000378:metabolism*; D006321:Heart / Q000187:drug effects*; D018942:Macrolides; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009206:Myocardium / Q000201:enzymology*; D013482:Superoxide Dismutase / Q000187:drug effects / Q000378:metabolism*; D015645:Tylosin / Q000031:analogs & derivatives* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; C052319:tilmicosin; D015645:Tylosin