Age, perfusion test results and dipyridamole reaction.
This retrospective study evaluated 933 patients referred for diagnostic nuclear medicine perfusion testing at 2 outpatient cardiology centers over a 7-month period. None of the patients were able to perform treadmill stress testing, and all received dipyridamole as a pharmacological stress. The authors found that 44% of the patients had an adverse reaction to dipyridamole. A correlational analysis of patients who did and did not have adverse reactions indicated that patients who exhibited some form of adverse reaction to dipyridamole were 10% more likely to have an abnormal perfusion test. In addition, age-group comparisons between patients 70 years or older and those younger than 70 years demonstrated that the younger group had a statistically greater probability of having an adverse reaction to dipyridamole.
Meyers
Art
A
Nuclear Medicine Program, Department of Health Physics, University of Nevada, Las Vegas, USA.
Topham
Lee
L
Ballow
Jim
J
Totah
David
D
Wilke
Reid
R
D000368:Aged; D000375:Aging; D016022:Case-Control Studies; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004176:Dipyridamole / Q000009:adverse effects; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes; D014665:Vasodilator Agents / Q000009:adverse effects
D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D014665:Vasodilator Agents; D004176:Dipyridamole; D017256:Technetium Tc 99m Sestamibi