title: Cutis laxa in seven members of a north-Indian family.
abstract: Congenital cutis laxa, characterized by cutaneous laxity and loose skin, may be autosomal dominant or autosomal recessive. The autosomal dominant variety is usually not associated with any systemic defects and has a good prognosis. We report an unusual family in which seven members were affected by the autosomal dominant variant of this disorder. We suggest that close monitoring of the cardiorespiratory systems may be worthwhile to detect any systemic complications, although these complications are rare in the autosomal dominant variant of cutis laxa.
authors.affiliation: Department of Dermatology and Venereology, Government Medical College and Hospital, Chandigarh, India.
authors.forename: Rashmi
authors.initials: R
authors.lastname: Sarkar
authors.forename: Charandeep
authors.initials: C
authors.lastname: Kaur
authors.forename: Amrinder J
authors.initials: AJ
authors.lastname: Kanwar
authors.forename: Srikanta
authors.initials: S
authors.lastname: Basu
mesh_terms: D002648:Child; D003241:Consanguinity; D003483:Cutis Laxa / Q000151:congenital / Q000235:genetics*; D005260:Female; D006801:Humans; D007194:India; D007223:Infant; D008297:Male; D010375:Pedigree