title: Association of body mass index with respiratory symptoms and atopy: results from the European Community Respiratory Health Survey.
abstract: BACKGROUND
  There are several reports showing that obese adults report more respiratory symptoms suggestive of asthma than those who are not obese.
  
  
  OBJECTIVE
  To determine the association of body mass index with respiratory symptoms and atopy in young adults
  
  
  METHODS
  Information collected from 15,454 participants in the European Community Respiratory Health Survey, a multicentre cross-sectional survey of young adults, was analysed to determine the association of body mass index with respiratory symptoms and atopy.
  
  
  RESULTS
  Men and women with a body mass index of greater than 30 were at an increased risk of wheeze with shortness of breath compared with those with a body mass of 20-24.99 (OR in men 1.85, 95% confidence interval 1.41-2.42; OR in women 2.03, 95% confidence interval 1.59-2.58). Similar associations were observed for other symptoms suggestive of asthma. Body mass index was not associated with 'hayfever or nasal allergies', specific IgE to house dust mite, grass or cat or with total IgE in men or women.
  
  
  CONCLUSIONS
  Reported associations of body mass index with symptoms suggestive of asthma are unlikely to be explained by a higher risk of atopy in the obese. Alternative explanations must be sought.
authors.affiliation: Department of Public Health Sciences, London, UK. deborah.jarvis@kcl.ac.uk
authors.forename: D
authors.initials: D
authors.lastname: Jarvis
authors.forename: S
authors.initials: S
authors.lastname: Chinn
authors.forename: J
authors.initials: J
authors.lastname: Potts
authors.forename: P
authors.initials: P
authors.lastname: Burney
mesh_terms: D000328:Adult; D000485:Allergens / Q000009:adverse effects / Q000276:immunology; D000818:Animals; D000918:Antibody Specificity / Q000276:immunology; D001249:Asthma / Q000453:epidemiology / Q000276:immunology*; D015992:Body Mass Index; D002415:Cats; D003430:Cross-Sectional Studies; D003625:Data Collection; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology / Q000276:immunology*; D007114:Immunization; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D008297:Male; D009765:Obesity / Q000453:epidemiology / Q000276:immunology; D039981:Pyroglyphidae / Q000276:immunology; D012111:Residence Characteristics; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000276:immunology
chemical_list: D000485:Allergens; D007073:Immunoglobulin E