title: Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2-year surveillance study.
abstract: BACKGROUND
  The reported frequency of recovery of fungi from infected nails varies according to the geographical area.
  
  
  OBJECTIVE
  To establish the nature of the causal agents in a sample of the Libyan population presenting with suspected onychomycosis.
  
  
  METHODS
  Samples were taken from the infected fingernails of 648 patients attending the Tripoli Medical Centre.
  
  
  RESULTS
  Samples from 500 patients proved positive for fungi following culturing, while 476 were potassium hydroxide and culture positive. Of the culture-positive samples, yeasts of the genus Candida (C. albicans, C. parapsilosis, C. glabrata, C. guillermondii and C. tropicalis) were the dominant cause of this condition in women (417 of 434, 96%) but were responsible for only a minority of cases in men (three of 66, 5%). In contrast, dermatophytes (Trichophyton violaceum, T. rubrum, T. mentagrophytes and Microsporum canis) were responsible for this condition in the majority of cases in men (53 of 66, 80%) but only 3% (15 of 434) of cases in women. The mould Aspergillus nidulans was isolated from the nails of 10 (15%) men and two (0.5%) women.
  
  
  CONCLUSIONS
  The data obtained in this study reveal an almost total separation of the aetiological agents responsible for onychomycosis based on gender.
authors.affiliation: Department of Medical Microbiology, Medical College, Al-Fateh University, PO Box 13497, Tripoli, Libya.
authors.forename: M S
authors.initials: MS
authors.lastname: Ellabib
authors.forename: M
authors.initials: M
authors.lastname: Agaj
authors.forename: Z
authors.initials: Z
authors.lastname: Khalifa
authors.forename: K
authors.initials: K
authors.lastname: Kavanagh
mesh_terms: D000293:Adolescent; D000328:Adult; D002175:Candida / Q000302:isolation & purification; D002177:Candidiasis / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006229:Hand Dermatoses / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D008002:Libya / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D014009:Onychomycosis / Q000453:epidemiology / Q000382:microbiology*; D017678:Sex Distribution