title: Acute quetiapine overdose in an eleven-year-old girl.
abstract: We present a case of acute Quetiapine (SeroQuel) overdose in an 11-y-old girl who ingested 1,300 mg (22.2 mg/kg bw). Initial lethargy developed within I h followed by an episode of agitation and combativeness 3 h after ingestion. After treatment with lorazepam the patient experienced extended somnolence followed by return to normal mental status 16 h after ingestion. No cardiotoxic or laboratory abnormalities were found. This is the first report of acute Quetiapine overdose in an adolescent and suggests a relatively benign clinical course.
authors.affiliation: Department of Emergency Medicine, University of Rochester Medical Center, NY 14642, USA.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Juhl
authors.forename: John G
authors.initials: JG
authors.lastname: Benitez
authors.forename: Susan
authors.initials: S
authors.lastname: McFarland
mesh_terms: D000208:Acute Disease; D014150:Antipsychotic Agents / Q000506:poisoning*; D002648:Child; D003937:Diagnosis, Differential; D003987:Dibenzothiazepines / Q000506:poisoning*; D062787:Drug Overdose / Q000175:diagnosis / Q000628:therapy; D004638:Emergency Treatment; D005260:Female; D006801:Humans; D000069348:Quetiapine Fumarate
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate