title: Measurement of cerebral oxygenation in neonates after vaginal delivery and cesarean section using full-spectrum near infrared spectroscopy.
abstract: To investigate whether or not the mode of delivery produces differences in cerebral oxygenation, cerebral hemoglobin oxygen saturation was measured using full-spectrum near infrared spectroscopy in 26 healthy term newborn infants immediately after birth. Infants in group 1 (n=20) were delivered vaginally, and those in group 2 (n=6) by elective cesarean section. Arterial oxygen saturation in the right hand was also measured simultaneously using a pulse oximeter. Changes in arterial oxygen saturation showed no significant difference between the two groups. The mean+/-S.D. of cerebral hemoglobin oxygen saturation in group 1 increased rapidly after birth, from 29+/-17% at 2 min to 68+/-6% at 8.5 min, followed by an almost constant value (66+/-7% at 15 min). In comparison, cerebral hemoglobin oxygen saturation in group 2 also increased rapidly until 8.5 min, but after this time decreased significantly to 57+/-5% at 15 min after birth. This indicates that the mode of delivery has a marked influence on cerebral oxygenation immediately after birth.
authors.affiliation: Department of Pediatrics Kagawa Medical University, 1750-1 Mikicho, Kitagun, Kagawa 761-0793, Japan. isobe@kms.ac.jp
authors.forename: Kenichi
authors.initials: K
authors.lastname: Isobe
authors.forename: Takashi
authors.initials: T
authors.lastname: Kusaka
authors.forename: Yuka
authors.initials: Y
authors.lastname: Fujikawa
authors.forename: Kensuke
authors.initials: K
authors.lastname: Okubo
authors.forename: Keiko
authors.initials: K
authors.lastname: Nagano
authors.forename: Saneyuki
authors.initials: S
authors.lastname: Yasuda
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kondo
authors.forename: Susumu
authors.initials: S
authors.lastname: Itoh
authors.forename: Konomu
authors.initials: K
authors.lastname: Hirao
authors.forename: Shoju
authors.initials: S
authors.lastname: Onishi
mesh_terms: D002585:Cesarean Section; D036861:Delivery, Obstetric; D006801:Humans; D007231:Infant, Newborn / Q000378:metabolism*; D010100:Oxygen / Q000032:analysis*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D013687:Telencephalon / Q000098:blood supply / Q000378:metabolism*; D013997:Time Factors
chemical_list: D010100:Oxygen