title: [Changes in local humoral immunity during stomach ulcer healing with laser and drug therapy].
abstract: The increase of the contents of serum IgA, IgG, IgM on the edge of long non-cicatrizing gastric ulcer was determined. At the same time the level of SIgA decreased in comparison with unaltered gastric mucosa. It is shown that the immunoglobulin content in the healed ulcer cicatrice depended on treatment method. The medicamentous therapy was accompanied by lowering of the contents of IgG, IgA, SIgA and by some increase of IgM level. The laser therapy is characterized by lowering of IgA, IgG, IgM level on a background of significant increase of SIgA content. The local humoral immunity after laser therapy was the same as in persons with unaltered gastric mucosa.
authors.affiliation: Central Research Institute of Gastroenterology, Moscow.
authors.forename: G N
authors.initials: GN
authors.lastname: Sokolova
authors.forename: T M
authors.initials: TM
authors.lastname: Tsaregorodtseva
authors.forename: M M
authors.initials: MM
authors.lastname: Zotina
mesh_terms: D000328:Adult; D000368:Aged; D000863:Antacids / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D000917:Antibody Formation; D003131:Combined Modality Therapy; D005753:Gastric Mucosa / Q000276:immunology / Q000473:pathology; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D028022:Low-Level Light Therapy; D008875:Middle Aged; D009942:Organometallic Compounds / Q000627:therapeutic use; D013270:Stomach / Q000276:immunology* / Q000473:pathology; D013276:Stomach Ulcer / Q000188:drug therapy / Q000276:immunology* / Q000628:therapy*
chemical_list: D000863:Antacids; D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D009942:Organometallic Compounds; C002791:bismuth tripotassium dicitrate
vernacular_title: Izmenenie mestnogo gumoral'nogo immuniteta v protsesse zazhivleniia iazv zheludka pod vliianiem lazernoĭ i medikamentoznoĭ terapii.