[Functional status of the intima and thrombocytic hemostasis in patients with symptoms of atherosclerosis of the cerebral and peripheral vessels].
The indices characterizing the state of lipid metabolism, endothelium of arteries and thrombocytic hemostasis were investigated. It was shown that in the zone of atherosclerotic stenosis of the arteries there were marked transformations of the endothelium followed by a decrease of their anticoagulatory properties. The cause and effect relationship between the disturbed thrombocytic hemostasis and lesions of the endothelium in atherosclerosis was confirmed. It is these factors which are the cause of frequent thromboembolic complications, especially in patients with lesions of the cerebral arteries. It is necessary to include methods of correction of the disturbed thrombocytic hemostasis in the complex treatment of patients with atherosclerosis.
Sedov
V M
VM
Shliakhto
E V
EV
Gordeev
N A
NA
Pizin
V M
VM
Sergeeva
E G
EG
Zinov'eva
N A
NA
D000368:Aged; D001161:Arteriosclerosis / Q000503:physiopathology* / Q000628:therapy; D001792:Blood Platelets / Q000502:physiology*; D001808:Blood Vessels / Q000473:pathology* / Q000503:physiopathology; D001921:Brain / Q000098:blood supply*; D006487:Hemostasis; D006801:Humans; D008875:Middle Aged; D017539:Tunica Intima / Q000503:physiopathology*
Funktsional'noe sostoianie intimy i trombotsitarnogo gemostaza u bol'nykh s proiavleniiami ateroskleroza mozgovykh i perifericheskikh sosudov.