title: Neonatal congenital heart disease and "complex" heart failure.
abstract: Hypoplastic left heart syndrome is a complex conglomerate of congenital cardiac abnormalities encountered in early life. Heart failure compensation and survival are intricately dependent on maintenance of ductal patency and avoidance of hyperoxic ventilation. While medical therapy is woefully inadequate, the staged Norwood procedure or cardiac transplantation remain the better options for treatment. Critically dependent on surgical outcomes, 5-year survival appears better with cardiac transplantation.
authors.affiliation: Cardiomyopathy and Heart Transplantation Center, Ochsner Clinic Foundation, New Orleans, LA 70121, USA.
authors.forename: Adam E
authors.initials: AE
authors.lastname: Berman
authors.forename: Theresa
authors.initials: T
authors.lastname: Roca
authors.forename: Patricia
authors.initials: P
authors.lastname: Uber
authors.forename: Mandeep
authors.initials: M
authors.lastname: Mehra
mesh_terms: D006328:Cardiac Catheterization; D016638:Critical Illness / Q000628:therapy; D006344:Heart Septal Defects, Atrial / Q000175:diagnosis / Q000601:surgery* / Q000628:therapy; D016027:Heart Transplantation; D006439:Hemodynamics; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000175:diagnosis / Q000601:surgery* / Q000628:therapy; D007223:Infant; D007231:Infant, Newborn