title: Pancreaticoduodenectomy for perforated gastric malignant lymphoma: report of a case.
abstract: We herein report the case of a 65-year old man with gastroduodenal malignant lymphoma (diffuse large B-cell type) accompanied with a bulbar perforation. A pancreaticoduodenectomy was performed because the duodenal second portion and pancreatic head were involved. However, extensive lymphadenectomy was not carried out because many lymph nodes were involved. The postoperative course was uneventful and CHOP therapy (pirarubicin 30 mg/m2, cyclophosphamide 500 mg/m2, vincristine 1 mg/m2, prednisolone 30 mg/m2) was started 1 month after surgery. Seven cycles of CHOP therapy markedly reduced the residual lesions including lymph nodes, and a computed tomography scan after the final chemotherapy revealed no obvious lesions. Complete remission was obtained and the patient was discharged 9 months after surgery.
authors.affiliation: Second Department of Surgery, Hamamatsu University School of Medicine, Japan.
authors.forename: Tuyoshi
authors.initials: T
authors.lastname: Shoji
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Konno
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Tanaka
authors.forename: Megumi
authors.initials: M
authors.lastname: Baba
authors.forename: Kinji
authors.initials: K
authors.lastname: Kamiya
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kaneko
authors.forename: Akira
authors.initials: A
authors.lastname: Igarashi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nakamura
mesh_terms: D000368:Aged; D004386:Duodenum / Q000473:pathology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology / Q000601:surgery*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000601:surgery*; D008297:Male; D009361:Neoplasm Invasiveness; D010166:Palliative Care; D010179:Pancreas / Q000473:pathology; D016577:Pancreaticoduodenectomy; D012422:Rupture, Spontaneous; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery*