Extensive facial clefting in a patient with Goltz syndrome: multidisciplinary treatment of a previously unreported association.
Goltz syndrome is a rare, X-linked dominant, multisystem disorder found almost exclusively in female patients. Although the cutaneous features predominate in most reports, characteristic abnormalities are also frequently present in the musculoskeletal system and facial region. We report a female infant born with a severe form of Goltz syndrome that included an extremely wide facial cleft, an abnormality not previously reported in a patient with this disorder. Her management demonstrates the advantages of a multidisciplinary approach to effectively care for patients with severe craniofacial abnormalities.
Ascherman
Jeffrey A
JA
Department of Surgery, Division of Plastic Surgery, Columbia-Presbyterian Medical Center, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA. jaa7@columbia.edu
Knowles
Sean L
SL
Troutman
Kenneth C
KC
D002972:Cleft Palate / Q000150:complications*; D005147:Facial Bones / Q000002:abnormalities*; D005260:Female; D005489:Focal Dermal Hypoplasia / Q000150:complications*; D006801:Humans; D007223:Infant; D010348:Patient Care Team