[From structural to functional genomics: theoretical and applied aspects].
The paper considers the results of studies of human genome and several eukariotic genomes, which have led to the establishment of the new genetic subject Structural Genomics and some other scientific areas. Particular attention is given to Proteomics considered to be the most developed section of Functional Genomics. The systems approach is ascertained to underlie proteomic strategy to study the protein products of gene expression with an ultimate goal of drawing up complete protein indices for definite organisms, such as proteomes, human proteomes in particular. The studies carried out at the Research Center of Medical Genetics, Russian Academy of Medical Sciences, have been used as an example to show that advances in Functional Genomics and the data of proteomic studies may be employed both for solution of theoretical problems and for different applied purposes (for development of diagnostic methods, for control of products derived from genetically modified plants, as well as during cellular therapy).
Shishkin
S S
SS
D015894:Genome, Human; D006801:Humans; D020543:Proteome
D020543:Proteome
Ot strukturnoĭ genomiki k funktsional'noĭ: teoreticheskie i prikladnye aspekty.