New onset systemic lupus erythematosus with pheochromocytoma.
We describe a patient with positive antinuclear and anti-Smith antibodies, proteinuria, and thrombocytopenia suggesting systemic lupus erythematosus (SLE). During hospitalization, the patient developed labile hypertension, tachycardia, and intermittent fever. A computer tomography scan of the abdomen showed an extraadrenal mass, which was confirmed as a pheochromocytoma. After removal of the pheochromocytoma, the patient's symptoms resolved and her serology normalized. Previous case reports describe SLE patients with adrenal pheochromocytomas that presented many years after the diagnosis of lupus. This is a novel case of pheochromocytoma discovered at the onset of SLE, with resolution of SLE manifestations shortly after its removal.
Lin
Antony T H
AT
Department of Medicine, UCLA School of Medicine, USA.
Min
Yoon
Y
Clements
Philip J
PJ
Morris
Robert
R
Shayestehfar
Babak
B
Mankin
Leonard
L
Wong
Andrew L
AL
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D000315:Adrenalectomy; D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D010673:Pheochromocytoma / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones