title: Bilateral submandibular salivary gland swelling--a report of chronic sialodochitis with eosinophilia.
abstract: A case of bilateral swelling of the submandibular salivary glands is presented. The histopathological features were diffuse periductal sclerosis with a lymphoplasmacytic infiltrate which was rich in eosinophils. Some acinar atrophy was seen. Salivary ducts showed mucous and squamous prosoplasia, with focal inspissated mucin. Numerous dilated and congested blood vessels were prominent throughout the stroma. These features overlapped with those of Kimura's disease and angiolymphoid hyperplasia with eosinophils. The features of these conditions and a differential diagnosis are discussed.
authors.affiliation: Division of Oral Pathology, Department of Diagnostic Sciences, Faculty of Health Sciences, University of Stellenbosch, Private Bag XI, Tygerberg. mrda@gerga.sun.ac.za
authors.forename: Mark R
authors.initials: MR
authors.lastname: Darling
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Phillips
authors.forename: Jason H
authors.initials: JH
authors.lastname: Erasmus
mesh_terms: D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000175:diagnosis; D001284:Atrophy; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009077:Mucins / Q000032:analysis; D018987:Salivary Ducts / Q000473:pathology*; D012598:Sclerosis; D012793:Sialadenitis / Q000473:pathology*; D013364:Submandibular Gland Diseases / Q000473:pathology*
chemical_list: D009077:Mucins