Changes in the chemical composition of surfactant-like particles secreted by rat small intestine in response to different dietary fats.
Consumption of dietary oil, viz., corn, fish, coconut, or olive, induced the secretion of surfactant-like particles (SLP) in rat intestine. These lipoprotein particles differ in (i) levels of alkaline phosphatase activity, (ii) lipid composition, and (iii) FA composition in response to feeding of different oils. The secreted particles had similar buoyancy (1.07-1.08 g/mL) and cholesterol/phospholipid molar ratios (0.61-0.72) except that feeding coconut oil to rats produced SLP with a low (0.18) cholesterol/phospholipid molar ratio compared to control animals. It is concluded from these observations that feeding different oils induces the secretion of lipoprotein particles in rat intestine with different chemical compositions.
Kalra
Seema
S
Department of Biochemistry, Panjab University, Chandigarh, India.
Mahmood
Safrun
S
Nagpaul
J P
JP
Mahmood
Akhtar
A
D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism; D000818:Animals; D002784:Cholesterol / Q000032:analysis; D004041:Dietary Fats / Q000494:pharmacology*; D005227:Fatty Acids / Q000032:analysis; D007421:Intestine, Small / Q000187:drug effects* / Q000378:metabolism*; D008297:Male; D009821:Oils / Q000494:pharmacology; D010743:Phospholipids / Q000032:analysis / Q000097:blood; D051381:Rats; D017208:Rats, Wistar; D013501:Surface-Active Agents / Q000737:chemistry* / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood
D004041:Dietary Fats; D005227:Fatty Acids; D009821:Oils; D010743:Phospholipids; D013501:Surface-Active Agents; D014280:Triglycerides; D002784:Cholesterol; D000469:Alkaline Phosphatase