Dissociation of different conformations of ubiquitin ions.
The fragmentation pathways of different conformations of three charge states of ubiquitin ions are examined using ion mobility/collisional activation/time-of-flight techniques. Mass spectra for fragments for different conformers of a single charge state appear to be identical (within the experimental reproducibility). These results are consistent with a mechanism in which different conformers of each charge state rearrange to similar dissociation transition states prior to fragment formation.
Badman
Ethan R
ER
Department of Chemistry, Indiana University, Bloomington 47405, USA.
Hoaglund-Hyzer
Cherokee S
CS
Clemmer
David E
DE
D008401:Gas Chromatography-Mass Spectrometry; D008968:Molecular Conformation; D021241:Spectrometry, Mass, Electrospray Ionization; D025801:Ubiquitin / Q000737:chemistry*
D025801:Ubiquitin