title: A case of intraductal papillary-mucinous carcinoma of the pancreas with the onset of acute pancreatitis.
abstract: Intraductal papillary-mucinous carcinoma of the pancreas has been reported with increasing frequency. We report a case with intraductal papillary-mucinous carcinoma of the pancreas and discuss surgical treatment and current imaging modalities. A case with intraductal papillary-mucinous carcinoma was analyzed by radiological findings and clinical course. A 47-year-old man developed abdominal pain and nausea. Computed tomography showed a diffusely dilated main pancreatic duct. Duodenoscopy showed a patulous orifice of the pancreas with massive mucus secretion, but the pancreatic juice was not positive for malignant cells. Endoscopic retrograde cholangiopancreatography revealed a markedly dilated pancreatic duct extending from the body to the tail of the pancreas. Distal pancreatectomy was performed with splenectomy and lymph nodes dissection. Histopathological diagnosis was intraductal papillary-mucinous carcinoma. Endoscopic retrograde cholangiopancreatography is useful for diagnosing intraductal papillary mucin-producing tumors. To avoid unnecessary total pancreatectomy and preserve pancreatic function, intraoperative frozen section examination is widely available for the surgical treatment of intraductal papillary mucin-producing tumors.
authors.affiliation: Department of Surgery, Tone Chuo Hospital, 1855-1, Higashiharashinmachi, Numata-City, Gunma 378-0053, Japan.
authors.forename: Kunio
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Tsuzuki
authors.forename: Tetsu
authors.initials: T
authors.lastname: Ando
authors.forename: Masao
authors.initials: M
authors.lastname: Sekihara
authors.forename: Takashi
authors.initials: T
authors.lastname: Hara
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Ishibashi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Ohno
authors.forename: Minako
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kuwano
mesh_terms: D000208:Acute Disease; D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000601:surgery; D000231:Adenocarcinoma, Papillary / Q000150:complications* / Q000601:surgery; D021441:Carcinoma, Pancreatic Ductal / Q000150:complications* / Q000601:surgery; D002760:Cholangiopancreatography, Endoscopic Retrograde; D005629:Frozen Sections; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000601:surgery; D010195:Pancreatitis / Q000150:complications*; D014057:Tomography, X-Ray Computed