[Tissular cestodiasis: role of helper type 1 and 2 t-lymphocytes].
Cysticercosis and hydatidosis are parasitic diseases caused by larvae of Taenia solium and Echinococcus sp., respectively. Parasitic diseases are useful models for in vivo studies of effector functions of T helper cell subsets 1 and 2, (called Th1 and Th2 on the basis of the pattern of cytokines they produce). The polarization to Th1 or Th2 is related to protective or permissive immune responses in these diseases. The role of Th1 and Th2 lymphocytes in tissue cestodiasis (cysticercosis and hydatidosis) has been studied in experimentally infected mice and in human patients; study results suggest that in individuals with cysticercosis or hydatidosis, the cellular immune response is polarized to Th2, while individuals in whom parasites are killed or their growth is limited, have an immune cellular response that is polarized towards Th1. The English version of this paper is available at: http://www.insp.mx/salud/index.html.
López-Moreno
Héctor Samuel
HS
Departamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Avenida Instituto Politécnico Nacional No. 2508, México, D.F., México. hlopez@mail.cinvestav.mx
D000818:Animals; D003551:Cysticercosis / Q000276:immunology*; D004195:Disease Models, Animal; D004443:Echinococcosis / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D051379:Mice; D008815:Mice, Inbred Strains; D018417:Th1 Cells / Q000502:physiology*; D018418:Th2 Cells / Q000502:physiology*
Cestodiasis tisulares: participación de los linfocitos T cooperadores 1 y 2.