title: [Drug resistant pulmonary tuberculosis: problems of diagnosis and treatment in hospital conditions].
abstract: The number of drug-resistant forms of pulmonary tuberculosis increases every year. The diagnosis of drug resistance of Mycobacterium tuberculosis (MBT) is rather difficult, up-to-date (molecular-and-genetic) methods should be applied. 236 patients with active pulmonary tuberculosis and massive bacterial excretion were investigated in Central Military Clinical Tubercular Hospital. 97 (41.1%) of them had drug resistant MBT (1 drug resistance was revealed in 15.5%, two drugs--in 28.8% and three and more drugs--in 55.7%). Rifampicin resistance was the highest one (40%). The authors propose the complex schemes of drug resistance prophylaxis and decrease in the patients with pulmonary tuberculosis.
authors.forename: V A
authors.initials: VA
authors.lastname: Suslov
authors.forename: V A
authors.initials: VA
authors.lastname: Moskalenko
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D024901:Drug Resistance, Multiple, Bacterial; D006772:Hospitals, Military / Q000706:statistics & numerical data* / Q000639:trends*; D006801:Humans; D008887:Military Medicine; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D016133:Polymerase Chain Reaction / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents
vernacular_title: Lekarstvenno-ustoĭchivyĭ tuberkulez legkikh: voprosy diagnostiki i lecheniia v statsionarnykh usloviiakh.