title: [Different therapeutic approaches for chronic diffuse liver lesions using ornicetil, lactulose, etimizol and corinfar].
abstract: Different therapeutic regimens were tried in 67 patients with hepatic cirrhosis and in 54 patients with chronic hepatitis depending on the leading pathological syndrome. Treatment schemes involved the use of the drug ornicetil in patients having acute episodes of portal systemic encephalopacy, lactulose in those presenting with an increased content of ammonia in the blood and symptoms of chronic portal systemic encephalopacy; etimizol was given to those patients with an apperant antioxidant imbalance. Differentiated approaches to the institution of curative measures permitted improving considerably the patients' medical rehabilitation, achieving regression of pathological manifestations. It has been found out that the above drugs exert a positive effect on the cytolytic and mesenchimal-inflammatory syndromes and will, we believe, come to be widely used for treating diffuse lesions of the liver.
authors.forename: Ie M
authors.initials: IeM
authors.lastname: Neĭko
authors.forename: Z M
authors.initials: ZM
authors.lastname: Mytnyk
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Holovach
mesh_terms: D005042:Etimizol / Q000627:therapeutic use*; D006501:Hepatic Encephalopathy / Q000188:drug therapy; D006521:Hepatitis, Chronic / Q000188:drug therapy; D006801:Humans; D007792:Lactulose / Q000627:therapeutic use*; D008103:Liver Cirrhosis / Q000188:drug therapy; D008107:Liver Diseases / Q000188:drug therapy*; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D009952:Ornithine / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D007792:Lactulose; C002118:ornithine alpha-ketoglutarate; D009952:Ornithine; D009543:Nifedipine; D005042:Etimizol
vernacular_title: Dyferentsiĭovani pidkhody do likuvannia khronichnykh dyfuznykh urazhen' pechinky iz zastosuvanniam ornitsetylu, laktulozy, etymizolu ta korynfaru.