title: Concise synthesis and enzymatic resolution of L-(+)-homophenylalanine hydrochloride.
abstract: The N-acetyl-homophenylalanine ethyl ester was synthesized by a simple three-step-reaction strategy. L-(+)-homophenylalanine hydrochloride with 98% ee was obtained through a kinetic resolution process using industrial enzyme alcalase. Compared with other methods, this strategy has the advantage of economical and simple procedure giving high product optical purity.
authors.affiliation: Department of Chemical Engineering, Chemistry and Environmental Science, New Jersey Institute of Technology, University Heights, Newark 07102, USA.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhao
authors.forename: Robert G
authors.initials: RG
authors.lastname: Luo
authors.forename: Dean
authors.initials: D
authors.lastname: Wei
authors.forename: Sanjay V
authors.initials: SV
authors.lastname: Malhotra