A direct comparison of noninvasive coronary angiography by electron beam tomography and navigator-echo-based magnetic resonance imaging for the detection of restenosis following coronary angioplasty.
OBJECTIVE
To compare electron beam tomography (EBT) with MR imaging (MRI) for detection of restenosis after coronary angioplasty (PTCA).


METHODS
One hundred eighteen patients after PTCA were investigated. By EBT, 50 axial images were acquired (3-mm slice thickness, 120-160 mL radiographic contrast agent). MRI was performed using respiratory-gated sequences (24-48 cross-sections, 2-mm slice thickness, 20 mL Gd-DTPA). EBT and MRI images were evaluated concerning high-grade post-PTCA restenosis (> or = 70%) and validated against coronary angiography.


RESULTS
In EBT, 28 patients and in MRI, 31 patients were not evaluable. In the remaining patients, sensitivity for restenosis detection was 90% in EBT (17/19) and 73% in MRI (11/15; P = 0.370). In EBT, specificity was significantly higher (66% vs. 49%, P = 0.043). Overall accuracy was 71% for EBT and 53% for MRI (P = 0.014).


CONCLUSIONS
For the detection of high-grade restenosis after PTCA, EBT demonstrated significantly higher accuracy than MRI.
Ropers
Dieter
D
Department of Internal Medicine, Biometry, and Epidemiology, University of Erlangen-Nuernberg, Erlangen, Germany. dieter.ropers@rzmail.uni-erlangen.de
Regenfus
Matthias
M
Stilianakis
Nikolaos
N
Birke
Susanne
S
Kessler
Winfried
W
Moshage
Werner
W
Laub
Gerhard
G
Daniel
Werner G
WG
Achenbach
Stephan
S
D015906:Angioplasty, Balloon, Coronary; D003287:Contrast Media; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000175:diagnosis*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D019786:Gadolinium DTPA