title: [Pathogenetic validation of xidiphone use in combined therapy for periodontal diseases].
abstract: It is well grounded for the application of a preparation from group bisphosphonates xydiphone is justified (reasonable). For treatment and preventive maintenance of a tooth stone for want of periodontal inflammation. Is shown on 30 patients with acute parodontitis and at 10--with gingivitis (in a stage of a peaking), that the application of xydiphone will neutralize an alkaline response having a place up to treatment, due to what it(he) exhibits antiseptic of a property. Xydiphone, linking ionized Ca and free Fe, simultaneously hinders with activation of free--radical oxidation, reduces blood-flux and blocks process of crystallization.
authors.forename: A N
authors.initials: AN
authors.lastname: Seleznev
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Petrovich
authors.forename: L N
authors.initials: LN
authors.lastname: Kolobkova
authors.forename: S A
authors.initials: SA
authors.lastname: Kozlov
authors.forename: S S
authors.initials: SS
authors.lastname: Kachkaeva
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002118:Calcium / Q000378:metabolism; D002985:Clinical Protocols; D004359:Drug Therapy, Combination; D012968:Etidronic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005891:Gingivitis / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010084:Oxidation-Reduction; D010518:Periodontitis / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D007501:Iron; D012968:Etidronic Acid; D002118:Calcium
vernacular_title: Patogeneticheskoe obosnovanie primeneniia ksidifona v kompleksnoĭ terapii bolezneĭ parodonta.