[Effect of thyroliberin on contractility and electrical activity of isolated bovine lymphangions].
The role of regulatory peptides is the least explored part in the field of humoral regulation of lymphatics. In this paper we continue a systematic investigation of their effects on the lymphatic vessels of various animals. The effect of thyroliberin was studied on bovine mesenteric lymphatics. The isolated lymphatics contractility and smooth muscle cell electrical activity were investigated. Thyroliberin in ultra low concentrations (1 x 10(-13)-1 x 10(-18) M) exerts a considerable stimulating effect. The mechanism of the theroliberin ultra-low concentrations action and a possibility of the medical usage of the obtained results, are discussed.
Lelekova
T V
TV
Mechnikov Medical Academy, St. Petersburg.
Petunov
S G
SG
Sanzhieva
L Ts
LTs
Ashmarin
I P
IP
Orlov
R S
RS
D000818:Animals; D002417:Cattle; D004594:Electrophysiology; D066298:In Vitro Techniques; D008208:Lymphatic System / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008643:Mesentery; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology / Q000502:physiology*
D013973:Thyrotropin-Releasing Hormone
Deĭstvie tiroliberina na sokratitel'nuiu i élektricheskuiu aktivnost' izolirovannykh limfangionov byka.