Dendritic supports in organic synthesis.
An overview is presented of the recent developments in the use of dendritic supports in organic synthesis. Examples are presented of the application of dendritic supports in both liquid- and solid-phase organic synthesis. In liquid-phase synthesis, soluble dendrimers are used as the substrate support, while in solid-phase synthesis, 'dendronized' insoluble resins are used for this purpose. Selected examples of the synthesis of compound libraries on dendritic supports via combinatorial techniques are discussed.
Klein Gebbink
Robertus J M
RJ
Debye Institute, Department of Metal-Mediated Synthesis, Utrecht University, The Netherlands. r.j.m.kleingebbink@chem.uu.nl
Kruithof
Cornelis A
CA
van Klink
Gerard P M
GP
Van Koten
Gerard
G
D001709:Biotechnology / Q000379:methods; D002625:Chemistry, Organic / Q000379:methods*; D020650:Combinatorial Chemistry Techniques / Q000379:methods; D046911:Macromolecular Substances; D011108:Polymers / Q000138:chemical synthesis*
D046911:Macromolecular Substances; D011108:Polymers