One gene and one outcome? No way.
The world of molecular diagnostics is undergoing major change because of both technical advances and the availability of rapidly expanding genetic databases generated by the study of human genomics. These resources comprise an extraordinary opportunity to decipher the biological importance of genetic aberrations, and link our understanding with clinical utility. The challenge lies in sorting through the information and developing effective strategies to advance molecular diagnostics.
Chanock
Stephen
S
Section on Genomic Variation, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. sc83a@nih.gov
Wacholder
Sholom
S
D005819:Genetic Markers / Q000235:genetics; D005826:Genetics, Medical / Q000379:methods* / Q000639:trends*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods* / Q000639:trends*; D010353:Patient Education as Topic; D020641:Polymorphism, Single Nucleotide / Q000235:genetics
D005819:Genetic Markers