title: Inhibition of artificial secondary caries by fluoride-releasing adhesives on root dentin.
abstract: Fluoride-releasing materials can be expected to inhibit the secondary caries. The aim;of this study was to evaluate the effect of fluoride-releasing adhesives on inhibition of secondary caries in outer and wall lesions. Two commercial fluoride-releasing adhesives, Reactmer bond (RB) and One-up bond F (OB), and a commercial adhesive without fluoride release, Mac-bond II (MB), were used prior to placement of restorative materials without fluoride release, Lite-fil II A (LF) and Estelite (EL), and a fluoride-releasing restorative material, Reactmer paste (RP). Class V cavities prepared on extracted human premolars were restored with various combinations of the materials: MB/EL, OB/EL, RB/LF and RB/RP. The restored teeth were incubated in bacterial medium containing sucrose with Streptoccus mutans for 14 days. Microradiographs of specimens showed no wall lesions in all groups and an acid-resistant layer adjacent to the restoration in the caries-like lesion. OB/EL, RB/LF and RB/RP groups showed thicker layers than the MB/EL group. The RB/RP group formed the shallowest outer lesion among all groups. These results indicate that fluoride-releasing adhesives are effective in the prevention of wall lesions but exhibit little outer lesion inhibition. Therefore, combined restoration using a fluoride-releasing adhesive and fluoride-releasing restorative material should be selected to inhibit secondary caries.
authors.affiliation: Department of Operative Dentistry, Okayama University Dental School, Japan. iota@md.okayama-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Itota
authors.forename: S
authors.initials: S
authors.lastname: Nakabo
authors.forename: Y
authors.initials: Y
authors.lastname: Iwai
authors.forename: N
authors.initials: N
authors.lastname: Konishi
authors.forename: M
authors.initials: M
authors.lastname: Nagamine
authors.forename: Y
authors.initials: Y
authors.lastname: Torii
mesh_terms: D000704:Analysis of Variance; D003188:Composite Resins / Q000737:chemistry*; D003793:Dental Restoration, Permanent / Q000379:methods*; D003804:Dentin / Q000473:pathology; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D005460:Fluorides, Topical / Q000008:administration & dosage*; D005899:Glass Ionomer Cements / Q000737:chemistry; D006801:Humans; D008689:Methacrylates / Q000737:chemistry; D019279:Resin Cements / Q000737:chemistry; D017213:Root Caries / Q000517:prevention & control*; D055502:Secondary Prevention
chemical_list: D003188:Composite Resins; D017220:Dentin-Bonding Agents; D005460:Fluorides, Topical; D005899:Glass Ionomer Cements; C083468:Lite-fil CR; C452442:Mac Bond II; D008689:Methacrylates; C446260:One-Up-Bond F; D019279:Resin Cements; C086113:palfique estelite; C447779:reactmer bond; C465006:reactmer paste