Early detection of infantile pre-type 1 diabetes case with transient hyperglycemia.
The patient was an infant with transient hyperglycemia and decreased endogenous insulin secretion on intravenous glucose tolerance test (IVGTT) with the appearance of IA-2 autoantibodies (IA-2Ab), and we speculated that he was in the prediabetes stage. To our knowledge, this is the first case reported to be diagnosed as type 1 diabetes prior to clinical onset in Japan.
Hirai
Hiroki
H
Department of Pediatrics, Ehime University School of Medicine, Shigenobu, 791-0295, Ehime, Japan.
Kaino
Yukikazu
Y
Ito
Takuo
T
Takemoto
Koji
K
Ishimaru
Asako
A
Watanabe
Shohei
S
Kida
Kaichi
K
D001323:Autoantibodies / Q000097:blood; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000276:immunology; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology*; D008297:Male; D011236:Prediabetic State / Q000175:diagnosis* / Q000276:immunology; D015203:Reproducibility of Results; D014839:Vomiting
D001323:Autoantibodies; D006442:Glycated Hemoglobin; C096322:ICA512 autoantibody