HDAC's at work: everyone doing their part.
The interplay between histone acetyltransferases (HATs) and histone deacetylases (HDACs) is key to the dynamics of chromatin structure and function. A recent report of genome-wide, microarray maps of histone acetylation has uncovered the intragenic targets for six different yeast HDACs and has led to the discovery of new heterochromatin-like domains.
Peterson
Craig L
CL
Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
D000107:Acetylation; D000123:Acetyltransferases / Q000502:physiology*; D000818:Animals; D002843:Chromatin / Q000502:physiology*; D020869:Gene Expression Profiling; D051548:Histone Acetyltransferases; D006655:Histone Deacetylases / Q000502:physiology*; D020411:Oligonucleotide Array Sequence Analysis; D029701:Saccharomyces cerevisiae Proteins; D013329:Structure-Activity Relationship; D015003:Yeasts / Q000201:enzymology
D002843:Chromatin; D029701:Saccharomyces cerevisiae Proteins; D000123:Acetyltransferases; D051548:Histone Acetyltransferases; D006655:Histone Deacetylases