title: Depressive disorders preceding temporal lobe epilepsy.
abstract: In this study, we investigated three female patients given a diagnosis of temporal lobe epilepsy preceded by depression. It is notable that all the patients complained of abnormal sensations, either in the throat or oral. The depression in the three patients showed no improvement with antidepressants, but carbamazepine was effective for both epileptic seizures and depression. EEG should be performed on patients who develop antidepressant treatment-refractory depression accompanied by hypochondriacal complaints.
authors.affiliation: Laboratory of Molecular and Cellular Pathology, Hokkaido University Graduate School of Medicine, Kita 15, Nishi 7, Kita-ku, Sapporo, 060-8638, Japan. ugn58203@nifty.com
authors.forename: Shin
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Tamaki
authors.initials: T
authors.lastname: Miyamoto
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Morita
authors.forename: Motoji
authors.initials: M
authors.lastname: Yasuda
mesh_terms: D000368:Aged; D000657:Amoxapine / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy / Q000209:etiology*; D004351:Drug Resistance; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: D000927:Anticonvulsants; D000928:Antidepressive Agents; D018687:Antidepressive Agents, Second-Generation; D002220:Carbamazepine; D000657:Amoxapine