The first general method for Z-selective olefination of acylsilanes via ynolate anions providing multisubstituted alkenes.
We have developed the first general method for a stereoselective olefination of acylsilanes via ynolate anions to produce (Z)-beta-silyl-alpha,beta-unsaturated ester, which leads to tri- and tetrasubstituted alkenes.
Shindo
Mitsuru
M
Institute for Medicinal Resources, University of Tokushima, Sho-machi 1, Tokushima 770-8505, Japan. shindo@ph2.tokushima-u.ac.jp
Matsumoto
Kenji
K
Mori
Seiji
S
Shishido
Kozo
K