Disseminated Paecilomyces lilacinus infection in a patient with AIDS.
We describe a case of disseminated Paecilomyces lilacinus infection occurring in a patient with advanced HIV infection. P lilacinus is a ubiquitous environmental fungus that has been associated with infection in various immunocompromised hosts, in patients with invasive medical devices, and in contact-lens wearers. The clinical features, morphologic characteristics, and response to antifungal therapy in our patient are similar to findings reported in disseminated infection due to Penicillium marneffei, another opportunistic fungal infection in HIV-infected patients. We believe this to be the first report of infection with P lilacinus in a patient with AIDS.
Lovell
Roger D
RD
Department of Medicine, Carolinas Medical Center, Charlotte, NC, USA.
Moll
Matthew
M
Allen
James
J
Cicci
Leigh Goodwin
LG
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D010143:Paecilomyces / Q000302:isolation & purification*
D000935:Antifungal Agents; D000666:Amphotericin B