title: Brugada-like electrocardiographic pattern induced by fever.
abstract: The Brugada syndrome is characterized by a peculiar ST-segment elevation in the right precordial leads and the propensity to develop ventricular arrhythmias. Mutations in a cardiac sodium channel gene have been linked to this syndrome and some experimental data suggest that the dysfunction of the mutated channel can be temperature sensitive. This report describes a patient in whom a typical Brugada ECG pattern developed in relation to fever but could not be reproduced at normal temperature on administration offlecainide. This case suggests that in some patients a Brugada-like ECG may only manifest during a febrile state.
authors.affiliation: Department of Cardiology, University Hospital Virgen de la Arrixaca, Murcia, Spain. danielsaura@wanadoo.es
authors.forename: Daniel
authors.initials: D
authors.lastname: Saura
authors.forename: Arcadi
authors.initials: A
authors.lastname: García-Alberola
authors.forename: Pilar
authors.initials: P
authors.lastname: Carrillo
authors.forename: Domingo
authors.initials: D
authors.lastname: Pascual
authors.forename: Juan
authors.initials: J
authors.lastname: Martínez-Sánchez
authors.forename: Mariano
authors.initials: M
authors.lastname: Valdés
mesh_terms: D000368:Aged; D002037:Bundle-Branch Block / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005334:Fever / Q000150:complications*; D006801:Humans; D008297:Male