One-step ethynylation of silyl enol ether with chlorosilylethyne.
[reaction: see text] In the presence of GaCl(3), silyl enol ethers are ethynylated at the alpha-carbon atom with chlorotrimethylsilylethyne. This reaction can provide alpha-ethynylated aryl ketones possessing acidic alpha-protons without isomerization to conjugated allenyl ketones.
Arisawa
Mieko
M
Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Sendai 980-8578, Japan.
Amemiya
Ryo
R
Yamaguchi
Masahiko
M