[Moyamoya and Down syndrome: study conducted by meta-analysis].
We present a clinic-epidemiological study of two patients and meta-analysis (period 1977-2000 ) of the co-morbidity of the Down syndrome (DS) and moyamoya syndrome (MMS). Among the 42 patients listed in this survey, meta-analysis permitted to find the highest number of publications by researchers from Japan and United States, followed by Brazil and Italy; prevalence of cerebrovascular disease in suckling and pre school children; first symptomatology was hemiparesis (78.6%), speech disorders (26.2%); ischemic infarction (76.2%); recurring ischemic episodes (62%); bilateral impairment (83.3%). This analysis led to the conclusion that in the clinic-neurological investigation of DS patients with acute hemiparesis episodes, MMS should be included as the most probable diagnosis.
Junqueira
Paulo Alves
PA
Departamento de Neurologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP, Brasil. ppaj@terra.com.br
Moura-Ribeiro
Maria Valeriana L de
MV
D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D002533:Cerebral Angiography; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D009072:Moyamoya Disease / Q000150:complications* / Q000175:diagnosis; D020521:Stroke / Q000150:complications / Q000000981:diagnostic imaging; D014463:Ultrasonography
Síndrome de Down e Moyamoya: estudo através de metanálise.