Comparative evaluation of diclofenac and dexamethasone following strabismus surgery.
OBJECTIVE
To compare efficacy of topical diclofenac sodium 0.1% with dexamethasone 0.1% following strabismus surgery.


METHODS
In this study, 58 patients undergoing strabismus surgery were evaluated. They were randomized into two groups: 29 patients received topical 0.1% diclofenac (Group A), and 29 patients received 0.1% dexamethasone (Group B) for 4 weeks. The baseline parameters were similar in both groups. At each visit comprehensive ocular examination was performed to record patient discomfort, conjunctival inflammation, gap, and intraocular pressure. Follow-up visits were at 1 week, 2 weeks, and 4 weeks, postoperatively.


RESULTS
There was no statistically significant difference in the rate of resolution of the inflammation, conjunctival healing, and intraocular pressure except rise of intraocular pressure at the fourth postoperative week in group B (P value <0.001).


CONCLUSIONS
The results of this study suggest that diclofenac may be used as an alternative to dexamethasone after strabismus surgery.
Dadeya
Subhash
S
Guru Nanak Eye Center, Maulana Azad Medical College, New Delhi, India.
Kamlesh
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use*; D004008:Diclofenac / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D007429:Intraocular Pressure / Q000187:drug effects; D009883:Ophthalmic Solutions; D010149:Postoperative Pain / Q000188:drug therapy*; D011446:Prospective Studies; D011897:Random Allocation; D013285:Strabismus / Q000601:surgery*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D009883:Ophthalmic Solutions; D004008:Diclofenac; D003907:Dexamethasone