title: [Acute tubular necrosis with acute renal failure during the first month of treatment with 5-amino-salicylate (Pentasa(R))].
abstract: We report a case of acute tubular necrosis in a patient with Crohn's disease treated by 5-amino-salicylate (Pentasa(R)) since one month. Normalization of renal biological parameters occurred rapidly after treatment withdrawal. This case raises the question of the optimal modalities of monitoring of renal function during treatment with 5-amino-salicylate.
authors.affiliation: Service d'Hépato-Gastroentérologie, Centre Hospitalier Intercommunal Poissy/Saint Germain, 10, rue du champ Gaillard, 78303 Poissy Cedex, France.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Beaulieu
authors.forename: Philippe
authors.initials: P
authors.lastname: Rocher
authors.forename: Daniel
authors.initials: D
authors.lastname: Hillion
authors.forename: Dominique
authors.initials: D
authors.lastname: Nochy
authors.forename: Ruth
authors.initials: R
authors.lastname: Tennenbaum
authors.forename: René-Louis
authors.initials: RL
authors.lastname: Vitte
authors.forename: Claude
authors.initials: C
authors.lastname: Eugène
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007684:Kidney Tubules / Q000187:drug effects / Q000473:pathology*; D008297:Male; D019804:Mesalamine / Q000009:adverse effects*; D008875:Middle Aged; D009336:Necrosis
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine
vernacular_title: Insuffisance rénale aiguë par nécrose tubulaire aiguë au cours du premier mois de traitement par l'acide 5-amino-salicylique (Pentasa(R)).