title: [Treatment outcome after surgical management of osseous breast carcinoma metastases. Preventive stabilization vs. management after pathological fracture].
abstract: AIM OF THE STUDY, METHOD: The advantages of a prophylactic care of fracture-endangered, osseous metastasis of the mammary cancer stand opposite to the perioperative risk and to conservative alternatives. As a pathologic fracture cannot surely be excluded while performing a conservative proceeding, a retrospective trial was set up to compare the results of treatment after a pathologic fracture (n = 35) with those undergoing a prophylactic attendance (n = 44).
  
  
  RESULTS
  The intraoperative, cardio-pulmonary complications were distributed in balance totally amounting to 20.3% (n = 16). Intraoperative complications concerning surgical procedure (n = 3) exclusively occurred within the fracture group. Generally, postoperative complications arose in 20.3% (n = 16) of all cases, in which the patients belonging to the fracture group were increasingly afflicted [28.6% (n = 11/35) vs. 11.4% (n = 5/44); p < 0.02]. While there were no differences between both groups concerning the postoperative, surgery-technical complications, significantly more patients (91.8% [n = 40/44]) of the prophylactic-care group achieved a complete postoperative usability of the operated area than in the fracture-group [74.3% (n = 26/35)] (p < 0.05). The average survival time tended to be longer within the prophylactic-care group [19.3 +/- 15.6 month (prophylactic-care group) vs. 15.0 +/- 16.9 month (fracture group)].
  
  
  CONCLUSIONS
  The prophylactic treatment of fracture endangered, osseous metastasis of the mammary cancer leads to reduction of the general, postoperative complications compared to the patients with a pathologic fracture. Further, those patients have a better chance to recover full mobility after surgery. Considering the long survival time after the incidence of osseous metastasis at the mammary cancer a prophylactic treatment represents the method of first choice compared with the conservative treatment which persistently contains the risk of fracturing.
authors.affiliation: Klinik und Poliklinik für Orthopädie, Universität zu Köln, Josef-Stelzmann-Str. 9, 50924 Köln, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Popken
authors.forename: J
authors.initials: J
authors.lastname: Schmidt
authors.forename: H
authors.initials: H
authors.lastname: Oegur
authors.forename: U J
authors.initials: UJ
authors.lastname: Göhring
authors.forename: D P
authors.initials: DP
authors.lastname: König
authors.forename: F
authors.initials: F
authors.lastname: Braatz
authors.forename: M H
authors.initials: MH
authors.lastname: Hackenbroch
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery; D005593:Fracture Fixation, Internal; D017102:Fracture Healing / Q000502:physiology; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000401:mortality / Q000517:prevention & control / Q000601:surgery*; D006620:Hip Fractures / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery; D006801:Humans; D006810:Humeral Fractures / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery; D008875:Middle Aged; D011788:Quality of Life; D011859:Radiography; D012189:Retrospective Studies; D015996:Survival Rate
vernacular_title: Behandlungsergebnisse nach operativer Versorgung ossärer Mammakarzinommetastasen. Prophylaktische Stabilisierung vs. Versorgung nach pathologischer Fraktur.