Growth mechanism of the bacterial flagellar filament.
The growth of the bacterial flagellar filament occurs at its distal end by self-assembly of flagellin transported from the cytoplasm through the narrow central channel of the flagellum. The cap at the growing end is essential for its growth, remaining stably attached while permitting the flagellin insertion. The structure of the cap-filament analyzed by electron cryomicroscopy suggested a cap rotation mechanism to promote the flagellin self-assembly.
Yonekura
Koji
K
Protonic NanoMachine Project, ERATO, JST, Seika, Kyoto, Japan. yone@npn.jst.go.jp
Maki-Yonekura
Saori
S
Namba
Keiichi
K
D001426:Bacterial Proteins / Q000378:metabolism; D020285:Cryoelectron Microscopy; D005407:Flagella / Q000378:metabolism* / Q000648:ultrastructure; D005408:Flagellin / Q000378:metabolism; D012486:Salmonella typhimurium / Q000254:growth & development* / Q000648:ultrastructure
D001426:Bacterial Proteins; D005408:Flagellin; C076733:FlaD protein, Bacteria