Polycythemia vera in a 12-year-old girl: a case report.
A case of a 12-year-old girl presenting with headache and splenomegaly and fulfilling the diagnostic criteria of polycythemia vera is reported. Her peripheral blood values were as follows: hemoglobin 18 g/dL, red blood cells 7,000,000/mm3, while blood cells 22,000/mm, and platelets 1,248,000/mm3. Phlebotomy was performed initially but was ineffective. Afterward 100 mg/kg per day aspirin and 30/mg/kg per day hydroxyurea were given. The patient has been asypmtomatic for 1 year and her recent hemoglobin level is 15.5 g/dL, platelet count 922,000/mm3, and white blood cell 12,800/mm3. Polycythemia vera is an extremely uncommon disease in childhood and for this reason its treatment is not well established.
Turker
Meral
M
SSK Tepecik Teaching Hospital, Clinics of Pediatrics, Yenisehir Izmir, Turkey.
Ozer
Esra Arun
EA
Oniz
Haldun
H
Atabay
Berna
B
Yaprak
Isin
I
D001241:Aspirin / Q000627:therapeutic use; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D007958:Leukocyte Count; D018962:Phlebotomy; D010976:Platelet Count; D011087:Polycythemia Vera / Q000175:diagnosis* / Q000188:drug therapy; D013163:Splenomegaly
D006454:Hemoglobins; D001241:Aspirin; D006918:Hydroxyurea