Executive function profile of children with attention deficit hyperactivity disorder.
We explored the neuropsychological profile for executive functions of children with attention deficit hyperactivity disorder (ADHD) to assess whether problems associated with the two most cited relevant processes--inhibition and attentional problems--were the core of any executive function difficulty. A battery of executive function tests was administered to 31 children with a clinical diagnosis of ADHD and to 33 normal control participants, all aged between 7 and 12. The executive function battery encompassed a number of tasks, selected because each had multiple measures: a sustained attention reaction time task, a related vigilance task, an adaptation of the Hayling Sentence Completion Test, an adaptation of the Brixton Spatial Rule Attainment Test, a Letter Fluency task, a number Stroop task, and an "n-back" working memory task. The overall pattern of the results fit well with those obtained in previous studies as far as abnormalities of the ADHD group in the domain of inhibitory processes, attentional functions, and executive functions. The children with ADHD, although performing well on baseline tasks, performed more poorly than the controls on all the experimental tasks with one borderline exception: Letter Fluency, where the children with ADHD showed a very different pattern than most adult frontal lobe subgroups. However, there was no specific impairment on measures of inhibitory processes. In addition, strategy generation and use were severely affected in the ADHD group. Particular findings fitted well with disorders of a high-level effort system and of a monitoring system.
Shallice
Tim
T
Institute of Cognitive Neuroscience, University College London, England. t.shallice@ucl.ac.uk
Marzocchi
Gian Marco
GM
Coser
Silvano
S
Del Savio
Maria
M
Meuter
Renata F
RF
Rumiati
Raffaella I
RI
D000704:Analysis of Variance; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology*; D016022:Case-Control Studies; D002648:Child; D002755:Choice Behavior; D003072:Cognition Disorders / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology*; D004193:Discrimination Learning; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D009483:Neuropsychological Tests; D011340:Problem Solving; D011597:Psychomotor Performance; D011930:Reaction Time; D013647:Task Performance and Analysis