Reanalysis of the HIV-1 circulating recombinant form A/E (CRF01_AE): evidence of A/E/G recombination.
Circulating recombinant form (CRF) 01_AE caused an extensive HIV-1 epidemic in Thailand and Southeast Asia. Reanalysis of the recombination pattern of CRF01_AE suggested a more complicated pattern of mosaicism consisting of subtypes A, G, and E. These findings provide evidence that CRF01_AE originated from recombination between at least three different subtypes.
Magiorkinis
Gkikas
G
National Retrovirus Reference Center, Department of Hygiene and Epidemiology, Athens University Medical School, Athens, Greece.
Paraskevis
Dimitris
D
Magiorkinis
Emmanouil
E
Vandamme
Anne-Mieke
AM
Hatzakis
Angelos
A
D015497:HIV-1 / Q000145:classification / Q000235:genetics*; D006801:Humans; D009030:Mosaicism; D010802:Phylogeny; D011995:Recombination, Genetic