Biological and morphological changes in worms in mixed infection of Schistosoma mansoni and S. haematobium in hamsters.
Hamsters infected with Schistosoma mansoni and S. haematobium either simultaneously or after maturation of an initial infection with either schistosome species were examined to estimate the biological and morphological changes under mixed infection conditions. The results indicate a high level of acquired resistance. The degree of immunity was evidenced by the significant reduction in the worm load as well as in the size of mature worms. Some disturbance was observed in the worm distribution. The results are important for epidemiological and immunological uses, as well as in development of a vaccine from one species that might be effective against both species.
el-Assal
Faiza M
FM
Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt.
el-Nahal
Hussen M
HM
el-Garhy
Manal E
ME
Hassan
Soad I
SI
Zalat
Rabab S
RS
D000818:Animals; D006224:Cricetinae; D007113:Immunity, Innate; D012548:Schistosoma haematobium / Q000033:anatomy & histology / Q000276:immunology*; D012550:Schistosoma mansoni / Q000033:anatomy & histology / Q000276:immunology*; D012553:Schistosomiasis haematobia / Q000276:immunology* / Q000469:parasitology / Q000517:prevention & control; D012555:Schistosomiasis mansoni / Q000276:immunology* / Q000469:parasitology / Q000517:prevention & control; D014611:Vaccination