title: Age, perfusion test results and dipyridamole reaction.
abstract: This retrospective study evaluated 933 patients referred for diagnostic nuclear medicine perfusion testing at 2 outpatient cardiology centers over a 7-month period. None of the patients were able to perform treadmill stress testing, and all received dipyridamole as a pharmacological stress. The authors found that 44% of the patients had an adverse reaction to dipyridamole. A correlational analysis of patients who did and did not have adverse reactions indicated that patients who exhibited some form of adverse reaction to dipyridamole were 10% more likely to have an abnormal perfusion test. In addition, age-group comparisons between patients 70 years or older and those younger than 70 years demonstrated that the younger group had a statistically greater probability of having an adverse reaction to dipyridamole.
authors.affiliation: Nuclear Medicine Program, Department of Health Physics, University of Nevada, Las Vegas, USA.
authors.forename: Art
authors.initials: A
authors.lastname: Meyers
authors.forename: Lee
authors.initials: L
authors.lastname: Topham
authors.forename: Jim
authors.initials: J
authors.lastname: Ballow
authors.forename: David
authors.initials: D
authors.lastname: Totah
authors.forename: Reid
authors.initials: R
authors.lastname: Wilke
mesh_terms: D000368:Aged; D000375:Aging; D016022:Case-Control Studies; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004176:Dipyridamole / Q000009:adverse effects; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes; D014665:Vasodilator Agents / Q000009:adverse effects
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D014665:Vasodilator Agents; D004176:Dipyridamole; D017256:Technetium Tc 99m Sestamibi