title: In vitro activities of new quinolones against Brucella melitensis isolated in a tertiary-care hospital in Turkey.
abstract: We have evaluated the in vitro activities of seven fluoroquinolones against 69 strains of Brucella melitensis. According to their minimum inhibitory concentration for 90% growth (MIC(90)) values, the most active agent was found to be sparfloxacin (MIC(90) 0.12 mg/L) followed by levofloxacin, ciprofloxacin, ofloxacin (MIC(90) 0.50 mg/L) and grepafloxacin (MIC(90) 1 mg/L), gemifloxacin (MIC(90) 2 mg/L) and gatifloxacin (MIC(90) 4 mg/L).
authors.affiliation: Department of Medicine and Section of Infectious Diseases, Hacettepe University School of Medicine, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Kocagöz
authors.forename: M
authors.initials: M
authors.lastname: Akova
authors.forename: B
authors.initials: B
authors.lastname: Altun
authors.forename: D
authors.initials: D
authors.lastname: Gür
authors.forename: G
authors.initials: G
authors.lastname: Hasçelik
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D017347:Brucella melitensis / Q000187:drug effects* / Q000302:isolation & purification / Q000502:physiology; D002006:Brucellosis / Q000188:drug therapy; D024881:Drug Resistance, Bacterial; D024841:Fluoroquinolones; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests; D014421:Turkey
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones