Subsequent pregnancy experience in patients with molar pregnancy and gestational trophoblastic tumor.
Modern therapy for molar pregnancy and gestational trophoblastic tumors has resulted in high cure rates and preservation of fertility, even in the setting of metastatic disease requiring chemotherapy. Patients and their partners facing future pregnancy after treatment for gestational trophoblastic disease express fear related to risk of disease recurrence and outcome of subsequent pregnancies. Data from the New England Trophoblastic Disease Center on later pregnancies following complete and partial mole as well as persistent gestational trophoblastic tumor show that patients, in general, can anticipate normal subsequent pregnancy outcomes.
Garner
Elizabeth I O
EI
New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Lipson
Elizabeth
E
Bernstein
Marilyn R
MR
Goldstein
Donald P
DP
Berkowitz
Ross S
RS
D005260:Female; D031901:Gestational Trophoblastic Disease / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications / Q000453:epidemiology; D008499:Medical Records; D009364:Neoplasm Recurrence, Local / Q000150:complications / Q000453:epidemiology*; D009511:New England / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D014594:Uterine Neoplasms / Q000150:complications / Q000453:epidemiology*