title: A case of intramedullary spinal cord tumor producing human chorionic gonadotropin.
abstract: We experienced a case of a persistent trophoblastic disease associated with gradually progressive Brown-Sequard syndrome, which was found to be due to a primary intramedullary spinal cord germinoma with syncytiotrophoblastic giant cells (STGC). We performed both chemotherapy and radiotherapy on separate occasions. Although the chemotherapy appeared to be ineffective, radiotherapy resulted in the disappearance of spinal cord lesions for four years. We reported a case of intramedullary spinal cord germinoma with STGC for which radiotherapy was a better therapeutic modality.
authors.affiliation: Department of Neurology, School of Medicine, Keio University, Tokyo, Japan. tsasaki@med.keio.ac.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Sasaki
authors.forename: Takahiro
authors.initials: T
authors.lastname: Amano
authors.forename: Masaki
authors.initials: M
authors.lastname: Takao
authors.forename: Mamoru
authors.initials: M
authors.lastname: Shibata
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Shigematsu
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Fukuuchi
mesh_terms: D000328:Adult; D020295:Brain Stem Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000532:radiotherapy; D006063:Chorionic Gonadotropin / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000532:radiotherapy
chemical_list: D006063:Chorionic Gonadotropin