Immunoprophylaxis in pertussis.
Pertussis is one of the common paediatric infectious diseases and an important public health problem specially so in the developing countries. An effective vaccine against this disease is available and given along with diphtheria and tetanus toxoids. However, the association of systemic, especially the neurological, complications have made it a controversial agent. The preparation of vaccine, its complications and mechanism of production of complications are presented.
Deb
M
M
Department of Microbiology, Lady Hardinge Medical College, New Delhi-110001.
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D001886:Bordetella pertussis / Q000276:immunology; D004195:Disease Models, Animal; D006801:Humans; D009422:Nervous System Diseases / Q000139:chemically induced; D010567:Pertussis Vaccine / Q000008:administration & dosage / Q000009:adverse effects* / Q000737:chemistry / Q000276:immunology*; D010566:Virulence Factors, Bordetella / Q000276:immunology; D014917:Whooping Cough / Q000276:immunology* / Q000517:prevention & control*
D000942:Antigens, Bacterial; D010567:Pertussis Vaccine; D010566:Virulence Factors, Bordetella