title: Adhesion induced by mobile binders: dynamics.
abstract: We consider a vesicle bilayer loaded with molecules that can bind (upon contact) with a solid surface, following the classical model of Bell, Dembo, and Bongrand. We are interested in situations where the contact area varies with time: we assume that binders can then migrate via diffusion. The resulting dissipation and lag create a retarded force on the contact line, which could be significant in squeezing or rolling experiments. However, there are two cases where we expect the lag force to be ineffective: (i) separation by shrinking of an adhesive patch (where the Evans "tear out" process turns out to be less costly) and (ii) spontaneous growth of a patch from a point contact. In this last case, the lag force is weak, and we give detailed predictions for the growth laws.
authors.affiliation: PCC Institute Curie, 11 Rue P. et M. Curie, 75005 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Brochard-Wyart
authors.forename: Pierre-Gilles
authors.initials: PG
authors.lastname: de Gennes
mesh_terms: D002448:Cell Adhesion / Q000502:physiology*; D008024:Ligands; D008954:Models, Biological; D014783:Viscosity
chemical_list: D008024:Ligands