Cutis laxa in seven members of a north-Indian family.
Congenital cutis laxa, characterized by cutaneous laxity and loose skin, may be autosomal dominant or autosomal recessive. The autosomal dominant variety is usually not associated with any systemic defects and has a good prognosis. We report an unusual family in which seven members were affected by the autosomal dominant variant of this disorder. We suggest that close monitoring of the cardiorespiratory systems may be worthwhile to detect any systemic complications, although these complications are rare in the autosomal dominant variant of cutis laxa.
Sarkar
Rashmi
R
Department of Dermatology and Venereology, Government Medical College and Hospital, Chandigarh, India.
Kaur
Charandeep
C
Kanwar
Amrinder J
AJ
Basu
Srikanta
S
D002648:Child; D003241:Consanguinity; D003483:Cutis Laxa / Q000151:congenital / Q000235:genetics*; D005260:Female; D006801:Humans; D007194:India; D007223:Infant; D008297:Male; D010375:Pedigree