title: Uptake of acetaldehyde-modified (ethylated) low-density lipoproteins by mouse peritoneal macrophages.
abstract: The uptake of acetaldehyde-modified (ethylated) low-density lipoproteins (LDLs) by murine peritoneal macrophages is described and compared with the uptake of acetylated LDLs. The fluorescent marker DiI was used. No competition between ethylated and acetylated LDLs was observed. Ethylated LDL uptake was not inhibited by polyinosinic acid or fucoidin. Our conclusion is that uptake of ethylated and acetylated LDLs can be done by two different receptors.
authors.affiliation: Department of Genetics, Institute of Psychiatry and Neurology, Sobieskiego 1/9, 02-957, Warsaw, Poland. wehr@ipin.edu.pl
authors.forename: Hanna
authors.initials: H
authors.lastname: Wehr
authors.forename: Ewa
authors.initials: E
authors.lastname: Mirkiewicz
authors.forename: Maria
authors.initials: M
authors.lastname: Rodo
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Bednarska-Makaruk
mesh_terms: D000079:Acetaldehyde / Q000378:metabolism*; D000107:Acetylation; D000818:Animals; D006801:Humans; D008077:Lipoproteins, LDL / Q000378:metabolism*; D017737:Macrophages, Peritoneal / Q000378:metabolism*; D008297:Male; D051379:Mice
chemical_list: D008077:Lipoproteins, LDL; D000079:Acetaldehyde