Antibodies as effectors.
Antibodies are critical in protection against extracellular microbial pathogens. Although antibodies also play a role in transplant/tumor rejection and in autoimmune disease, this paper focuses on defense against bovine infections. Effector mechanisms of different bovine isotypes, subisotypes and allotypes are discussed. The importance of antigen specificity is also stressed.
Corbeil
L B
LB
Department of Pathology, School of Medicine, University of California, 200W. Arbor Dr., San Diego, CA 92103-8416, USA. lcorbeil@ucsd.edu
D000818:Animals; D000906:Antibodies / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D006192:Haemophilus Infections / Q000276:immunology / Q000662:veterinary; D007074:Immunoglobulin G / Q000145:classification / Q000276:immunology; D007132:Immunoglobulin Isotypes / Q000276:immunology; D014245:Trichomonas Infections / Q000276:immunology
D000906:Antibodies; D007074:Immunoglobulin G; D007132:Immunoglobulin Isotypes