Testing equality of cause-specific hazard rates corresponding to m competing risks among K groups.
In this paper, a class of tests is developed for comparing the cause-specific hazard rates of m competing risks simultaneously in K (> or = 2) groups. The data available for a unit are the failure time of the unit along with the identifier of the risk claiming the failure. In practice, the failure time data are generally right censored. The tests are based on the difference between the weighted averages of the cause-specific hazard rates corresponding to each risk. No assumption regarding the dependence of the competing risks is made. It is shown that the proposed test statistic has asymptotically chi-squared distribution. The proposed test is shown to be optimal for a specific type of local alternatives. The choice of weight function is also discussed. A simulation study is carried out using multivariate Gumbel distribution to compare the optimal weight function with a proposed weight function which is to be used in practice. Also, the proposed test is applied to real data on the termination of an intrauterine device.
Kulathinal
S B
SB
Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland.
Gasbarra
Dario
D
D005260:Female; D006801:Humans; D007434:Intrauterine Devices / Q000706:statistics & numerical data; D011247:Pregnancy; D011275:Pregnancy, Unwanted; D016016:Proportional Hazards Models; D018570:Risk Assessment