The concentration of plasma triacylglycerols in horses fed diets containing either medium chain triacylglycerols or an isoenergetic amount of starch or cellulose.
In a Latin square design, six horses were fed hay and concentrates with isoenergetic amounts of either starch, cellulose or medium chain triacylglycerols (MCT). The dietary variables provided on average 22% of total dietary net energy. Plasma triacylglycerols and other variables of lipid metabolism were determined. The experimental periods lasted 21 days. Blood samples were taken just before the morning meal and three and six hours later. The diet rich in MCT significantly raised the plasma level of triacylglycerols when compared to either the starch- or cellulose-rich diet. The plasma concentrations of 3-hydroxybutyrate, total cholesterol and phospholipids were significantly higher when the horses were fed the ration with MCT instead of either cellulose or starch. Postprandial insulin concentrations were lowest for the MCT diet, and concentrations of free fatty acids were highest. Lipoprotein lipase activity was not significantly different for the three diets. Our study does not support the idea that cellulose feeding generates sufficient acetic acid in the caecum and colon, so that it would enhance the provision of cytosolic acetyl-CoA which in turn would stimulate hepatic fatty acid synthesis and then raise plasma triacylglycerols.
Hallebeek
J M
JM
Department of Nutrition, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.152, 3508 TD Utrecht, The Netherlands. halleb@vet.uu.nl
Beynen
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AC
D020155:3-Hydroxybutyric Acid / Q000097:blood; D000818:Animals; D002482:Cellulose / Q000008:administration & dosage* / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D005227:Fatty Acids / Q000096:biosynthesis; D005260:Female; D006736:Horses / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D010743:Phospholipids / Q000097:blood; D011897:Random Allocation; D013213:Starch / Q000008:administration & dosage* / Q000378:metabolism; D014280:Triglycerides / Q000008:administration & dosage* / Q000097:blood* / Q000737:chemistry / Q000378:metabolism
D005227:Fatty Acids; D010743:Phospholipids; D014280:Triglycerides; D002482:Cellulose; D013213:Starch; D002784:Cholesterol; D020155:3-Hydroxybutyric Acid