title: A comparison of the cytologic and histologic features of meningiomas in four dogs.
abstract: The cytologic and histologic features of 2 intracranial and 2 spinal (extramedullary cervical) canine meningiomas were compared. Cerebrospinal fluid analysis in 2 cases revealed mild, mixed cell pleocytosis, primarily composed of small lymphocytes and monocytoid cells, with a moderate increase in total protein concentration. Cytologic features suggestive of meningioma included cells with both epithelial and mesenchymal characteristics and a tendency towards cell clustering. Tumor location also was useful in making a diagnosis. The 4 meningiomas differed histologically from one another, and included angioblastic, psammomatous, meningotheliomatous, and microcystic anaplastic types, which conformed to a classification scheme for human meningiomas. The classification scheme could not be applied to cytologic specimens.
authors.affiliation: Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA. kzimmerm@vt.edu
authors.forename: Kurt L
authors.initials: KL
authors.lastname: Zimmerman
authors.forename: Holly S.
authors.initials: HS
authors.lastname: Bender
authors.forename: G. Daniel
authors.initials: GD
authors.lastname: Boon
authors.forename: M. Renee
authors.initials: MR
authors.lastname: Prater
authors.forename: Catherine E.
authors.initials: CE
authors.lastname: Thorn
authors.forename: Don
authors.initials: D
authors.lastname: Prater
authors.forename: John L.
authors.initials: JL
authors.lastname: Robertson
authors.forename: Geoffrey K.
authors.initials: GK
authors.lastname: Saunders
authors.forename: D. Phillip
authors.initials: DP
authors.lastname: Sponenberg
authors.forename: Karen D.
authors.initials: KD
authors.lastname: Inzana
authors.forename: Otto I.
authors.initials: OI
authors.lastname: Lanz
authors.forename: Eric
authors.initials: E
authors.lastname: Wright