title: [Digital full field mammography: comparison between radiographic direct magnification and digital monitor zooming].
abstract: OBJECTIVE
  Our goal was to compare digital magnification mammograms with images zoomed from the digital contact mammogram in patients with microcalcifications.
  
  
  METHODS
  Fifty-five patients with 57 microcalcification clusters were evaluated with a FFDM system (Senographe 2000D, GE). In addition to a digital contact mammogram, a digital direct magnification mammogram (factor 1.8 [MAG1.8]) and an image zoomed from the contact mammogram with a magnification factor of 1.8 [ZOOM1.8] were obtained in each patient. The image quality (perfect = 5 points to inadequate = 1 point) and the characterization of microcalcifications (BI-RADS 2-5) were evaluated by 4 readers. The results were compared to histopathologic findings in 35 patients (37 lesions) and follow-up in 20 patients.
  
  
  RESULTS
  Histopathology revealed 16 benign and 21 malignant lesions. 20 patients had benign changes verified by long-term follow-up. Image quality of direct magnification FFDM was assessed superior (4.44 points) to zoomed images (4.14 points). Sensitivity was superior for direct magnification (97.5%) in comparison to the zoomed images (96.3%). However, specificity (MAG1.8: 34.3%, ZOOM1.8: 40%), PPV (MAG1.8: 47.5%, ZOOM1.8: 49.8%) and accuracy (MAG1.8: 58.1%, ZOOM1.8: 61.2%) were better with zooming technique. Deviation steps from best BI-RADS assessment were 0.45 for MAG1.8 and 0.44 for ZOOM1.8.
  
  
  CONCLUSIONS
  In patients with mammographic microcalcifications, monitor zooming of the digital contact mammogram is equivalent to direct magnification FFDM. Therefore, monitor zooming allows a reduction of the radiation exposure and an optimization of the work-flow.
authors.affiliation: Abteilung Diagnostische Radiologie, Georg-August-Universität Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen. uwe.fischer-weende@t-online.de
authors.forename: U
authors.initials: U
authors.lastname: Fischer
authors.forename: F
authors.initials: F
authors.lastname: Baum
authors.forename: S
authors.initials: S
authors.lastname: Obenauer
authors.forename: M
authors.initials: M
authors.lastname: Funke
authors.forename: K P
authors.initials: KP
authors.lastname: Hermann
authors.forename: E
authors.initials: E
authors.lastname: Grabbe
mesh_terms: D001941:Breast Diseases / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008327:Mammography / Q000295:instrumentation*; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D011856:Radiographic Image Enhancement / Q000295:instrumentation*; D011858:Radiographic Magnification / Q000295:instrumentation*; D012680:Sensitivity and Specificity
vernacular_title: Digitale Vollfeldmammographie: Vergleich zwischen radiographischer Direktvergrösserung und digitalem Monitorzooming.