[A comparison of effects of agents stabilizing or destroying the water structure on conformational changes of a DNA molecule in solutions exposed to gamma-irradiation].
It was shown that gamma-irradiation of water-ethanol and water-n-propanol solutions of DNA with doses of 10-30 Gy leads to a fall of the specific volume of the macromolecule upon the cooperative transition at a critical concentration of alcohol in solution at which the destroying of water structure by a nonelectrolyte occurs.
Pastoian
S V
SV
Physical Department, St. Petersburg State University, Ul'yanovskaya ul. 1, Petrodvorets, 198904 Russia.
Sushko
M L
ML
Mel'nik
B S
BS
Rumiantseva
I M
IM
Zyrianova
I M
IM
Zarubina
O P
OP
Frisman
E V
EV
D000433:1-Propanol / Q000737:chemistry; D001718:Birefringence; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry / Q000528:radiation effects*; D000431:Ethanol / Q000737:chemistry; D005720:Gamma Rays; D009690:Nucleic Acid Conformation; D012996:Solutions; D012997:Solvents; D014508:Urea / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D012996:Solutions; D012997:Solvents; D014867:Water; D000431:Ethanol; D014508:Urea; D004247:DNA; D000433:1-Propanol
Sravnenie vliianiia soedineniĭ, stabiliziruiushchikh i razrushaiushchikh strukturu vody, na konformatsionnye izmeneniia molekuly DNK pri gamma-obluchenii ee rastvorov.