[Hyperthermia combined with radiation therapy in the treatment of cancer patients].
Hyperthermia [HT] combined with radiation therapy [XRT] has been confirmed in several randomized studies to be more effective then XRT alone in various cancers. In this study we presented our experience using this combined modality. One hundred and fifty one HT sessions in 40 fields were delivered to 24 patients with breast cancer, melanoma and other tumors. Twelve patients [83 HT in 19 HT fields] were followed-up in a single institution. Complete and partial responses were seen in 9/19 [47%] and 8/19 [42%] HT fields during 2-12 months. Additional 2 HT fields were treated on an adjuvant basis [one due to positive deep surgical margins and the other due to a second local recurrence in chest wall]. We conclude that HT-XRT is an effective treatment and should widely be used in appropriately selected cancer patients.
Ben-Yosef
Rami
R
Radiobiology and Hyperthermia Laboratory, Radiotherapy Unit, Division of Oncology, Tel-Aviv Souraski Medical Center, Tel-Aviv.
D001943:Breast Neoplasms / Q000532:radiotherapy / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008545:Melanoma / Q000532:radiotherapy / Q000628:therapy; D009369:Neoplasms / Q000532:radiotherapy / Q000628:therapy*; D012878:Skin Neoplasms / Q000532:radiotherapy / Q000628:therapy; D016896:Treatment Outcome