A novel ophthalmic presentation of the Proteus syndrome.
OBJECTIVE
To report a patient with the Proteus syndrome who had ocular complications not previously described in the literature.


METHODS
Single observational case report.


METHODS
Retrospective review of the medical record and review of the literature.


RESULTS
The 26-year-old man has systemic features fulfilling the diagnostic criteria for the Proteus syndrome. His ocular abnormalities are myopia, mild calcific band keratopathy, cataract, abnormal vitreous structure, vitreous hemorrhage, a large chorioretinal mass, and a resolved serous retinal detachment.


CONCLUSIONS
Ocular complications are frequently reported in patients with the Proteus syndrome. Few of the patients reported in the literature have had comprehensive ocular examination by an ophthalmologist. Our patient is unique because he has been examined by ophthalmologists from childhood, and it is clear that the ocular findings may change with time. As far as we are aware, calcific band keratopathy, abnormal vitreous structure, and chorioretinal hamartoma associated with serous retinal detachment and vitreous hemorrhage have not previously been described.
Sheard
Richard M
RM
Department of Ophthalmology, Addenbrooke's Hospital, Cambridge, England.
Pope
F Michael
FM
Snead
Martin P
MP
D000328:Adult; D002114:Calcinosis / Q000175:diagnosis; D002386:Cataract / Q000175:diagnosis; D003316:Corneal Diseases / Q000175:diagnosis; D005124:Eye Abnormalities / Q000175:diagnosis*; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D009216:Myopia / Q000175:diagnosis; D016715:Proteus Syndrome / Q000175:diagnosis*; D012163:Retinal Detachment / Q000175:diagnosis; D012189:Retrospective Studies; D014823:Vitreous Hemorrhage / Q000175:diagnosis