[Micturition disturbances in Parkinson's disease. Clinical and urodynamic evaluation].
Urinary dysfunction in idiopathic Parkinson's disease (IPD) has already been described, however its incidence, urodynamic pattern, dependence on the severity of parkinsonism as well as improvement with levodopa treatment are not exactly known. The aim of the study was to evaluate the frequency of urinary disturbances in patients with idiopathic Parkinson's disease and their relationship to treatment with levodopa. The investigation was carried out on 41 IPD patients aged 37-84 (mean 61.6) years. The neurological examination, including evaluation of parkinsonism according to UP-DRS scale was conducted together with the urological tests, including uroflowmetry and cystometry. Patients with infection of the urinary tract and with prostate hypertrophy were excluded from the study. 32 (78%) patients had urinary symptoms: frequency in 27 cases (65%), urgency in 9 cases (21%), urge incontinence in 1 case and dysuria in 1 case. Disorders in urodynamic examination were found in 26 cases (63%); they were: detrusor hyperactivity in 21 cases (51%), prolonged time of micturition in 18 cases (44%) and decrease of maximum flow rate in 19 cases (46%). Detrusor hyperactivity was more frequent in patients with extended parkinsonian motor signs. The results of the examination indicate frequent urinary disturbances (70%) in IPD, which improve during treatment with increased dose of levodopa.
Krygowska-Wajs
Anna
A
Kliniki Neurologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie. krygowska@neuro.cm-uj.krakow.pl
Weglarz
Wiesław
W
Szczudlik
Zygmunt Dobrowolski Andrzej
ZD
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy*; D014555:Urination Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D014563:Urodynamics / Q000187:drug effects
D000978:Antiparkinson Agents; D007980:Levodopa
Zaburzenia oddawania moczu w chorobie parkinsona: ocena kliniczna i urodynamiczna.