BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.
BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through its web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.


BACKGROUND
Source code is available under the GNU public license at http://bioinformatics.fccc.edu/
Grant
J D
JD
Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. jd_grant@fccc.edu
Dunbrack
R L
RL
Manion
F J
FJ
Ochs
M F
MF
D003195:Computer Communication Networks; D003205:Computing Methodologies; D003628:Database Management Systems; D030541:Databases, Genetic; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D009317:National Library of Medicine (U.S.); D017421:Sequence Analysis; D014481:United States