Skeletal dysplasias and their effect on the respiratory system.
Children with skeletal dysplasia frequently have pulmonary disease which can be life threatening. These pulmonary problems are due to multiple aetiologies including thoracic and craniofacial anomalies predisposing to restrictive lung disease, upper airway obstruction and central apnoea. Recognition of pulmonary disease and early intervention improves the survival and quality of life for these children.
Mogayzel
P J
PJ
Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins School of Medicine, Baltimore, MD 21287-2533, USA. mogayzel@mail.jhmi.edu
Marcus
C L
CL
D001848:Bone Diseases, Developmental / Q000150:complications* / Q000503:physiopathology* / Q000628:therapy; D002648:Child; D006801:Humans; D008171:Lung Diseases / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy; D012137:Respiratory System / Q000503:physiopathology*