title: Chronic total occlusions: experience with fiber-optic guidance technology--optical coherence reflectometry.
abstract: Chronic total occlusions are difficult to treat and continue to challenge the interventional cardiologist. The primary difficulty is safely crossing the total occlusion with a guidewire before any revascularization can begin. One of the main reasons conventional and newer guidewires have not proven effective is simply the lack of visualization to safely steer the guidewire across the occlusion. This limitation can be overcome with new technology using a "forward-looking" fiber-optic guidance. The Safe-Steer TO (Total Occlusion) Crossing System is a new guidance system that uses optical coherence reflectometry to steer a guidewire through total occlusions. Optical coherence reflectometry uses algorithms to determine tissue types (plaque vs arterial wall) by measuring the intensity of the reflection of near-infrared light. The authors' clinical experience with the Safe-Steer System has met considerable success. With their initial 28 patients (7 women, 21 men) with known chronic total occlusions and confirmed ischemia, the primary success rate for the crossing the occlusion was 86% (24/28 cases). The average occluded lesion length was 41.1 +/- 30.8 mm. Our initial clinical experience demonstrates that the optical guidewire is a viable technology in the treatment of chronic total occlusions.
authors.affiliation: Phoenix Heart Center, St. Luke's Medical Center, 525 North 18th St., Suite 504, Phoenix, AZ 85006, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Morales
authors.forename: R R
authors.initials: RR
authors.lastname: Heuser
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D003327:Coronary Disease / Q000473:pathology* / Q000601:surgery*; D005260:Female; D005336:Fiber Optic Technology / Q000295:instrumentation*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D055100:Optical Fibers