title: [Preimplantation genetic diagnosis].
abstract: Preimplantation genetic diagnosis is a very early form of prenatal diagnosis aimed at eliminating embryos carrying serious genetic diseases before implantation. The basic techniques currently used involve embryo biopsy, the polymerase chain reaction and fluorescence in situ hybridization. In the current review, a number of problems arising from the use of these technologies as well as the possible solutions and new developments are discussed.
authors.affiliation: Reproductive Medical Center, First Affiliated Hospital, Sun Yat-Sen University Sciences, Guangzhou, Guangdong, 510080 P. R. China. Jiaozexu@yahoo.com
authors.forename: Zexu
authors.initials: Z
authors.lastname: Jiao
authors.forename: Guanglun
authors.initials: G
authors.lastname: Zhuang
mesh_terms: D020732:Cytogenetic Analysis; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D011247:Pregnancy; D019836:Preimplantation Diagnosis; D020401:Primed In Situ Labeling