[Effect of perftoran emulsion ventilation of lungs on the pulmonary surfactant system in patients with acute lung injury syndrome].
The condition was studied of the pulmonary surfactant system in those patients with the syndrome of acute lung injury who had been placed on a partial emulsion ventilation of the lungs. The study of the surface tension of the endobronchial washings was made with the aid of the modified Willihelm balance before the start of the treatment and at post-treatment day 4, 6 and 8. The initial level of surface tension has been found out to be increased by 8.9%. The controlled indices were gradually returning to normal in the wake of the emulsion ventilation of the lungs. Partial emulsion ventilation of the lungs with perftoran makes for a prompt and complete restoration of surface activity of the pulmonary surfactant within 7 days. We consider it essential that a conventional intensive therapy of the acute lung injury syndrome be supplemented by partial emulsion ventilation of the lungs with perftoran.
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D001992:Bronchoalveolar Lavage Fluid; D004655:Emulsions; D005466:Fluorocarbons / Q000494:pharmacology*; D006801:Humans; D011663:Pulmonary Surfactants / Q000187:drug effects* / Q000502:physiology; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000628:therapy*; D013500:Surface Tension; D013577:Syndrome
D004655:Emulsions; D005466:Fluorocarbons; D011663:Pulmonary Surfactants; C063334:perftoran
Vplyv emul'siĭnoï ventyliatsiï lehen' "perftoranom" na surfaktantnu systemu lehen' u khvorykh iz syndromom hostroho lehenevoho poshkodzhennia.