title: Minimal number of chromatographic test parameters for the characterisation of reversed-phase liquid chromatographic stationary phases.
abstract: This paper focuses on the classification or differentiation of RP-HPLC columns based on measured chromatographic properties. A chemometric study has been conducted on a published data set consisting of 85 RP-HPLC columns and on a data set consisting of 47 self-tested columns. Principal component analysis enables determination of the number of parameters necessary for a rational differentiation. The results show that reducing the number of parameters for such differentiation still allows classification of the columns just as a higher number did. It is shown that three test parameters produce a classification similar to that obtained with five parameters.
authors.affiliation: Vrije Universiteit Brussel, Department of Pharmaceutical and Biomedical Analysis, Belgium.
authors.forename: Timea
authors.initials: T
authors.lastname: Iványi
authors.forename: Yvan
authors.initials: Y
authors.lastname: Vander Heyden
authors.forename: Dóra
authors.initials: D
authors.lastname: Visky
authors.forename: Peggy
authors.initials: P
authors.lastname: Baten
authors.forename: Jacques
authors.initials: J
authors.lastname: De Beer
authors.forename: István
authors.initials: I
authors.lastname: Lázár
authors.forename: D L
authors.initials: DL
authors.lastname: Massart
authors.forename: Eugène
authors.initials: E
authors.lastname: Roets
authors.forename: Jos
authors.initials: J
authors.lastname: Hoogmartens
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D006863:Hydrogen-Ion Concentration