title: Synthesis of dimeric lactose and dimeric (sialyl) Lewis(X) glycolipids.
abstract: To investigate structural requirements for the homophilic interaction between carbohydrates on planar model membranes, divalent derivatives with enforced proximity between the two carbohydrate epitopes (lactose, Lewis(X), and sialyl Lewis(X)) were synthesized by use of a dimeric membrane anchor as scaffold.
authors.affiliation: Fachbereich Chemie, Universität Konstanz, Box M725, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Gege
authors.forename: Richard R
authors.initials: RR
authors.lastname: Schmidt
mesh_terms: D002240:Carbohydrate Sequence; D019281:Dimerization; D006017:Glycolipids / Q000138:chemical synthesis* / Q000737:chemistry*; D007785:Lactose / Q000138:chemical synthesis* / Q000737:chemistry*; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry*; D000080506:Sialyl Lewis X Antigen
chemical_list: D006017:Glycolipids; D009844:Oligosaccharides; D000080506:Sialyl Lewis X Antigen; D007785:Lactose