title: [Treatment protocol for cervical carcinoma].
abstract: BACKGROUND
  Cervical cancer is the second most common cancer in women worldwide and the second cause of cancer death among women. About 95% (90% in developed countries) of invasive carcinomas are of squamous types, and 5% (10% in developed countries) are adenocarcinomas. FIGO classification of cervical carcinomas, based on clinical staging and prognostic factor dictate therapeutic procedures and help in designing treatment protocols.
  Surgical therapy includes conization, radical hysterectomy with pelvic lymphadenectomy and palliative operation--urinary diversion and colostomy. Radiotherapy, brachytherapy and teletherapy are most recently combined with chemotherapy as concurrent chemoradiation.
  
  
  CONCLUSIONS
  No change in therapeutic modalities will ever decrease mortality rate of cervical carcinoma as much as education, prevention and early screening. The 5-year survival for locally advanced disease has not improved during the last 40 years as a result of failure to deliver therapy to the paraaortic region. Paraaortic lymph nodes should be evaluated before therapy planning by different imaging procedures, or more exactly by surgical staging: laparoscopy or laparotomy. Radical operations of cervical carcinoma should be performed by experienced surgeons, educated for this type of operation, with sufficient number of cases.
authors.affiliation: Klinika za operativnu onkologiju, ginekolosko odeljenje, Institut za onkologiju, Sremska Kamenica.
authors.forename: Tamara
authors.initials: T
authors.lastname: Vujkov
authors.forename: Milica
authors.initials: M
authors.lastname: Zivaljević
authors.forename: Petar
authors.initials: P
authors.lastname: Novaković
authors.forename: Marko
authors.initials: M
authors.lastname: Erak
authors.forename: Jelka
authors.initials: J
authors.lastname: Rajović
authors.forename: Aljosa
authors.initials: A
authors.lastname: Mandić
mesh_terms: D024221:Antineoplastic Protocols; D002277:Carcinoma / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000628:therapy*
vernacular_title: Protokol lecenja karcinoma grlića materice.