title: [Pulmonary problems associated with lymphoplasmacytic lymphoma (Waldenström's macroglobulinemia)].
abstract: A 62-year-old man, known for some years due to lymphoplasmacytic lymphoma, was admitted with progressive dyspnoea. Multiple lung infiltrates were found upon X-ray examination. Because of the suspicion of an infection, a bronchoscopy with bronchoalveolar lavage was performed. No infectious cause could be established. Upon cytological examination, a highly increased level of kappa-positive B-lymphoid cells was found, as is seen in cases of lymphoplasmacytic lymphoma (Waldenström's macroglobulinaemia). Following chemotherapy, the dyspnoea lessened and the pulmonary infiltrates disappeared. In patients with a lymphoproliferative disorder, pulmonary infiltrates due to infection are found relatively frequently. This case report highlights a rare complication of the disease, namely pulmonary infiltrates caused by infiltration of lymphoplasmacytic cells, emphasising the importance of cytological examination of broncho-alveolar lavage fluid.
authors.affiliation: Afd. Longziekten, Academisch Ziekenhuis Rotterdam-Daniel den Hoed Kliniek, Rotterdam.
authors.forename: J G J V
authors.initials: JG
authors.lastname: Aerts
authors.forename: F
authors.initials: F
authors.lastname: de Jongh
authors.forename: C E
authors.initials: CE
authors.lastname: van Iperen
authors.forename: K H
authors.initials: KH
authors.lastname: Lam
authors.forename: H C
authors.initials: HC
authors.lastname: Hoogsteden
authors.forename: J P A M
authors.initials: JP
authors.lastname: van Meerbeeck
mesh_terms: D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D004417:Dyspnea / Q000209:etiology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
vernacular_title: Longklachten bij lymfoplasmocytair lymfoom (ziekte van Waldenström).