After 130 years, the molecular mechanism of action of nitroglycerin is revealed.
Ignarro
Louis J
LJ
Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. lignarro@mednet.ucla.edu
D000818:Animals; D001711:Biotransformation; D002460:Cell Line; D008928:Mitochondria / Q000201:enzymology; D009566:Nitrates / Q000378:metabolism; D020030:Nitric Oxide Donors / Q000494:pharmacology; D009573:Nitrites / Q000378:metabolism; D005996:Nitroglycerin / Q000493:pharmacokinetics / Q000494:pharmacology*; D010088:Oxidoreductases / Q000378:metabolism; D014665:Vasodilator Agents / Q000494:pharmacology
D009566:Nitrates; D020030:Nitric Oxide Donors; D009573:Nitrites; D014665:Vasodilator Agents; D010088:Oxidoreductases; C109196:nitroglycerin reductase; D005996:Nitroglycerin