Listerial endocarditis in a penicillin-allergic woman successfully treated with a combination of 4 drugs.
A 69-y-old woman with bioprosthetic endocarditis due to Listeria monocytogenes developed an allergic reaction after beginning ampicillin treatment. She was cured with the combination of trimethoprim-sulfamethoxazole, rifampicin and teicoplanin. No immune deficiency was found in the patient.
Benes
Jiri
J
Department of Infectoius Disease, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic. benesj@cesnet.cz
Viechova
Jana
J
Kabelkova
Maria
M
Horova
Blanka
B
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000150:complications* / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D008089:Listeria monocytogenes / Q000302:isolation & purification*; D008088:Listeriosis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D010406:Penicillins / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D012293:Rifampin / Q000627:therapeutic use; D017334:Teicoplanin / Q000627:therapeutic use; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D010406:Penicillins; D017334:Teicoplanin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D012293:Rifampin