What's new in respiratory allergy?
The past 10 years have seen important advances in our understanding of allergic respiratory disease and the targets for potential therapies. Sensitisation and triggering of allergic reactions now appear to be better understood at a clinical and molecular level. Environmental intervention studies are underway attempting to reduce the sensitisation and the triggering of symptoms. Therapeutic intervention studies targeting key pathways in the allergic cascade are also taking place. This paper will assess both of these aspects of respiratory allergy, updating readers on the new evidence in our quest to understand how and when sensitisation occurs and also how we might be able to control triggered reactions using targeted therapeutics against specific elements of the allergic cascade.
Cunningham
S
S
Royal Hospital for Sick Children, Edinburgh, Scotland, UK.
D002648:Child; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy; D012120:Respiration Disorders / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy