title: [Monitoring of fluoride levels in children receiving fluorinated milk for a long time and time course of their permanent teeth].
abstract: Measurements of fluorine concentrations in 1320 urine samples collected from 440 children in the city of Maikop showed low levels of fluorine (0.43-0.72 mg) in this group in comparison with the groups receiving prophylactic treatment with optimal safe doses of fluorine with milk (0.88-1.19 mg). Consumption of physiological amounts of fluorine does not lead to its accumulation in the body even after long (up to 5 years) consumption of fluorinated milk. Permanent ratio between the values in the control and prophylactic groups allows less frequent monitoring of fluorine levels: during the first month of prevention and then after 2 and 4 years of prophylaxis with fluorinated milk. Clinical evaluation of anticaries efficiency of fluorinated milk in 920 children aged 6-8 years (309 in the control and 611 in prophylactic groups) showed a significant decrease of caries prevalence (by 12.5-24.5%) and intensity in permanent teeth (by 50.6-56.7% by the CDL index and by 47.6-52.9% by the CDLp index) after 3-5 years of regular consumption of fluorinated milk.
authors.forename: I G
authors.initials: IG
authors.lastname: Pereslegina
authors.forename: E M
authors.initials: EM
authors.lastname: Kuz'mina
authors.forename: A G
authors.initials: AG
authors.lastname: Kolesnik
mesh_terms: D000818:Animals; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D003731:Dental Caries / Q000178:diet therapy* / Q000503:physiopathology / Q000517:prevention & control; D003733:Dental Caries Susceptibility; D004326:Drinking; D005459:Fluorides / Q000008:administration & dosage* / Q000009:adverse effects / Q000652:urine*; D006801:Humans; D008892:Milk / Q000378:metabolism; D008991:Monitoring, Physiologic; D013997:Time Factors; D014070:Tooth / Q000502:physiology
chemical_list: D002327:Cariostatic Agents; D005459:Fluorides
vernacular_title: Monitoring postupleniia ftorida v organizm deteĭ, dlitel'noe vremia poluchaiushchikh ftorirovannoe moloko, i dinamika kariesa ikh postoiannykh zubov.