Malignant mullerian mixed tumor arising from ovarian serous carcinoma: a clinicopathologic and molecular study of two cases.
The clinical, histologic, and molecular pathologic features of two cases of malignant mullerian mixed tumor (MMMT) arising from ovarian papillary serous carcinoma are presented. Identical p53 mutations were detected in the primary ovarian carcinoma and the subsequent MMMT in each case.
Gallardo
Alberto
A
Department of Pathology, Hospital Santa Creu i Sant Pau, Autonomous University of Barcelona, Spain.
Matias-Guiu
Xavier
X
Lagarda
Helena
H
Catasus
Lluis
L
Bussaglia
Elena
E
Gras
Esther
E
Suarez
Daniel
D
Prat
Jaime
J
D000368:Aged; D018284:Cystadenocarcinoma, Serous / Q000235:genetics / Q000473:pathology*; D004312:Douglas' Pouch / Q000473:pathology; D005260:Female; D016158:Genes, p53 / Q000235:genetics; D006801:Humans; D019656:Loss of Heterozygosity; D018200:Mixed Tumor, Mullerian / Q000235:genetics / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000235:genetics / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000235:genetics / Q000473:pathology*; D017354:Point Mutation