title: Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides.
abstract: A microfluidic analytical system for the separation and detection of organic peroxides, based on a microchip capillary electrophoresis device with an integrated amperometric detector, was developed. The new microsystem relies on the reductive detection of both organic acid peroxides and hydroperoxides at -700 mV (vs. Ag wire/AgCl). Factors influencing the separation and detection processes were examined and optimized. The integrated microsystem offers rapid measurements (within 130 s) of these organic-peroxide compounds, down to micromolar levels. A highly stable response for repetitive injections (RSD 0.35-3.12%; n = 12) reflects the negligible electrode passivation. Such a "lab-on-a-chip" device should be attractive for on-site analysis of organic peroxides, as desired for environmental screening and industrial monitoring.
authors.affiliation: Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA. joewang@nmsu.edu
authors.forename: Joseph
authors.initials: J
authors.lastname: Wang
authors.forename: Alberto
authors.initials: A
authors.lastname: Escarpa
authors.forename: Martin
authors.initials: M
authors.lastname: Pumera
authors.forename: Jason
authors.initials: J
authors.lastname: Feldman
mesh_terms: D004563:Electrochemistry / Q000379:methods*; D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000379:methods*; D008904:Miniaturization; D009930:Organic Chemicals / Q000032:analysis*; D010545:Peroxides / Q000032:analysis*
chemical_list: D009930:Organic Chemicals; D010545:Peroxides