title: Alpha,beta-unsaturated 4-oxo acids in heterocylic synthesis. II. Behavior of 3-(1,1-dioxadibenzothein-4-oyl)acrylic acid towards carbon nucleophiles under Michael reaction condition.
abstract: 3-(1,1-Dioxadibenzothien-4-oyl)acrylic acid (1) was condensed with compounds containing active methylene groups under Michael reaction conditions to furnish the Michael adducts (lactones 2a-c, lactams 3a-c, ketones 4a,b). The behavior of these adducts toward the action of hydrazine hydrate were investigated. The compounds were tested for their biological properties.
authors.affiliation: Chemistry Department, Faculty of Science, Benha University, Benha, Egypt.
authors.forename: A A F
authors.initials: AA
authors.lastname: Wasfy
authors.forename: M S
authors.initials: MS
authors.lastname: Amine
authors.forename: M M H
authors.initials: MM
authors.lastname: Arief
authors.forename: S G
authors.initials: SG
authors.lastname: Donia
authors.forename: A A
authors.initials: AA
authors.lastname: Aly
mesh_terms: D000179:Acrylates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013057:Spectrum Analysis
chemical_list: D000179:Acrylates; D002264:Carboxylic Acids; C036658:acrylic acid