Epithelial plasma cell granuloma-like tumors of the lungs. A hitherto unrecognized tumor.
We present two cases of benign pulmonary epithelial tumors located in the middle lobes of the lungs. The patients were women of 56 and 36 years of age. The tumors were morphologically similar to plasma cell granuloma. At the tumor periphery, the lesion cells formed thin organoid rows of cells and vague trabeculae, disclosing morphologically their epithelial nature. In addition, the tumors strongly stained immunohistochemically with antibodies to cytokeratins, TTF-1 and EMA, and they were negative for immunoglobulin kappa and lambda light chains. We are not aware of similar tumors described in the literature, and we suggest the name "epithelial plasma cell granuloma-like tumors" for these lesions.
Michal
Michal
M
Department of Pathology, Faculty Hospital, Pilsen, Czech Republic. michal@medima.cz
Mukensnabl
Petr
P
D000328:Adult; D014408:Biomarkers, Tumor; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000378:metabolism / Q000473:pathology*; D016726:Plasma Cell Granuloma, Pulmonary / Q000378:metabolism / Q000473:pathology*
D014408:Biomarkers, Tumor