title: [An experimental study for tumor detection by indocyanine green with near-infrared topography].
abstract: We studied tumor detection by indocyanine green (ICG) with near-infrared topography in rat experimental tumors: hepatoma AH109A and osteosarcoma POB 102. Time-intensity curves and topograms after ICG injection were obtained in tumors and surrounding normal tissues. Intensities in tumors were slowly reduced, and intensities in normal tissues were rapidly reduced, resulting in positive tumor image in topogram. It is concluded that near-infrared topography enhanced by ICG is useful for cancer detection.
authors.affiliation: Department of Radiology, Hirosaki University School of Medicine.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ohata
authors.forename: Yoshinao
authors.initials: Y
authors.lastname: Abe
authors.forename: Tomisato
authors.initials: T
authors.lastname: Miura
authors.forename: Tatsusuke
authors.initials: T
authors.lastname: Sato
mesh_terms: D000818:Animals; D001859:Bone Neoplasms / Q000175:diagnosis*; D005260:Female; D007208:Indocyanine Green; D008114:Liver Neoplasms, Experimental / Q000175:diagnosis*; D012516:Osteosarcoma / Q000175:diagnosis*; D051381:Rats; D019265:Spectroscopy, Near-Infrared
chemical_list: D007208:Indocyanine Green