The role of glycopeptides in the treatment of intravascular catheter-related infections.
There is increasing concern over multiresistant staphylococcci in catheter-associated infections. Local infections due to coagulase-negative staphylococci are usually resolved by removal of the intravascular catheter. However, if the device should remain for a certain period of time, e.g. to complete a course of chemotherapy, the antibiotic lock technique with a glycopeptide should be considered. In case of septic embolism to the lung caused by a multiresistant Staphylococccus aureus or Enterococcus faecium, systemic therapy with glycopeptides, streptogramins or linezolid must be employed.
Graninger
W
W
University Hospital Vienna, Department of Internal Medicine I, Division of Infectious Diseases and Chemotherapy,Vienna, Austria. wolfgang.graninger@akh-wien.ac.at
Assadian
O
O
Lagler
H
H
Ramharter
M
M
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003428:Cross Infection / Q000188:drug therapy*; D004696:Endocarditis / Q000628:therapy; D005260:Female; D006020:Glycopeptides; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000188:drug therapy; D018805:Sepsis / Q000188:drug therapy; D012778:Short Bowel Syndrome / Q000378:metabolism; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus / Q000254:growth & development
D000900:Anti-Bacterial Agents; D006020:Glycopeptides