Recurring staphylococcal scalded skin syndrome-like bullous mastocytosis: the utility of cytodiagnosis and the rapid regression with steroids.
We report a male infant with onset of an extensive bullous eruption at the age of 45 days. Staphylococcal scalded skin syndrome (SSSS) was suspected. Bullous mastocytosis was diagnosed by cytodiagnosis and confirmed by histologic examination. Three serious relapses were noted in a 2-year follow-up, and SSSS was again suspected because of high fever and leukocytosis with neutrophilia in an infectious context. Cytodiagnosis revealed the presence of mast cells and permitted rapid diagnosis of recurrences of bullous mastocytosis. Systemic corticotherapy dramatically improved the cutaneous lesions and general symptoms. This case report emphasizes the utility of cytodiagnosis in extensive blistering diseases in infancy and the possibility of obtaining rapid healing by using steroids.
Has
Cristina
C
Department of Dermatology, University Hospital, Saint-Etienne, France.
Misery
Laurent
L
David
Louis
L
Cambazard
Frédéric
F
D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D013206:Staphylococcal Scalded Skin Syndrome / Q000175:diagnosis; D014582:Urticaria Pigmentosa / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D005938:Glucocorticoids; D011239:Prednisolone