title: Phage lambda red-mediated adaptive mutation.
abstract: Replacement of the recBCD genes of Escherichia coli with the red recombination genes of bacteriophage lambda results in a strain in which adaptive mutation occurs at an elevated frequency. Like RecBCD-dependent adaptive mutation, Red-mediated adaptive mutation is dependent upon recA and ruvABC functions.
authors.affiliation: Department of Molecular Genetics & Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. anthony.poteete@umassmed.edu
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Poteete
authors.forename: Hsinju R
authors.initials: HR
authors.lastname: Wang
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Foster
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics; D010582:Bacteriophage lambda / Q000235:genetics*; D002876:Chromosomes, Bacterial; D004926:Escherichia coli / Q000235:genetics*; D007763:Lac Operon; D009154:Mutation; D011995:Recombination, Genetic; D014169:Transformation, Bacterial