[Complex diagnosis of congenital cranial dysostosis in children].
Ten patients (aged 3-15 years) with congenital cranial dysostosis were examined by a pediatrician, geneticist, gastroenterologist, neuropathologist, ophthalmologist, endocrinologist, and orthopaedist. In addition to the clinical signs characteristic of hereditary multiple developmental defects, the study revealed changes in the jaws and temporomandibular joint and local factors promoting the progress of deformations of the jaws. Manifest and inapparent pathological changes and dysfunctions in gastrointestinal organs were paralleled by dysfunctions of the central and autonomic nervous systems, risk of maxillofacial and general deformations, and signs of congenital disorders in calcium, lactic acid, and pyridoxine metabolism. The results necessitate analyses of the blood and urine and development of new methods for the diagnosis of congenital cranial dysostosis and improvement of methods for the correction of this condition.
Iakubov
R K
RK
Azimov
M I
MI
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000293:Adolescent; D001842:Bone and Bones / Q000002:abnormalities; D002648:Child; D002675:Child, Preschool; D003394:Craniofacial Dysostosis / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism; D003884:Dermoid Cyst / Q000175:diagnosis; D004423:Ear / Q000002:abnormalities; D005124:Eye Abnormalities / Q000175:diagnosis; D005146:Facial Asymmetry / Q000151:congenital* / Q000175:diagnosis / Q000235:genetics; D005260:Female; D005704:Gallbladder / Q000002:abnormalities; D006053:Goldenhar Syndrome / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D008297:Male; D014059:Tongue / Q000002:abnormalities
Kompleksnaia diagnostika vrozhdennykh kraniodizostozov u deteĭ.