Calcium signaling through protein kinases. The Arabidopsis calcium-dependent protein kinase gene family.
In plants, numerous Ca(2+)-stimulated protein kinase activities occur through calcium-dependent protein kinases (CDPKs). These novel calcium sensors are likely to be crucial mediators of responses to diverse endogenous and environmental cues. However, the precise biological function(s) of most CDPKs remains elusive. The Arabidopsis genome is predicted to encode 34 different CDPKs. In this Update, we analyze the Arabidopsis CDPK gene family and review the expression, regulation, and possible functions of plant CDPKs. By combining emerging cellular and genomic technologies with genetic and biochemical approaches, the characterization of Arabidopsis CDPKs provides a valuable opportunity to understand the plant calcium-signaling network.
Cheng
Shu-Hua
SH
Department of Genetics, Harvard Medical School, MA 02114, USA.
Willmann
Matthew R
MR
Chen
Huei-Chi
HC
Sheen
Jen
J
D048948:14-3-3 Proteins; D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics / Q000254:growth & development; D029681:Arabidopsis Proteins; D020013:Calcium Signaling / Q000235:genetics / Q000502:physiology*; D002135:Calcium-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D002244:Carbon / Q000378:metabolism; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D018506:Gene Expression Regulation, Plant / Q000187:drug effects; D007113:Immunity, Innate; D005810:Multigene Family; D009154:Mutation; D009584:Nitrogen / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D010766:Phosphorylation; D010802:Phylogeny; D010935:Plant Diseases / Q000209:etiology; D010937:Plant Growth Regulators / Q000494:pharmacology; D010940:Plant Proteins; D018514:Plant Structures / Q000254:growth & development / Q000502:physiology; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism*; D013379:Substrate Specificity; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism; D017871:Calcium-Calmodulin-Dependent Protein Kinases
D048948:14-3-3 Proteins; D029681:Arabidopsis Proteins; D002135:Calcium-Binding Proteins; D002244:Carbon; D009584:Nitrogen; D010743:Phospholipids; D010937:Plant Growth Regulators; D010940:Plant Proteins; D011494:Protein Kinases; D014446:Tyrosine 3-Monooxygenase; C490306:ATCDPK1 protein, Arabidopsis; D017871:Calcium-Calmodulin-Dependent Protein Kinases; C490307:ATCDPK2 protein, Arabidopsis