Synthesis of dimeric lactose and dimeric (sialyl) Lewis(X) glycolipids.
To investigate structural requirements for the homophilic interaction between carbohydrates on planar model membranes, divalent derivatives with enforced proximity between the two carbohydrate epitopes (lactose, Lewis(X), and sialyl Lewis(X)) were synthesized by use of a dimeric membrane anchor as scaffold.
Gege
Christian
C
Fachbereich Chemie, Universität Konstanz, Box M725, Germany.
Schmidt
Richard R
RR
D002240:Carbohydrate Sequence; D019281:Dimerization; D006017:Glycolipids / Q000138:chemical synthesis* / Q000737:chemistry*; D007785:Lactose / Q000138:chemical synthesis* / Q000737:chemistry*; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry*; D000080506:Sialyl Lewis X Antigen
D006017:Glycolipids; D009844:Oligosaccharides; D000080506:Sialyl Lewis X Antigen; D007785:Lactose