Phage lambda red-mediated adaptive mutation.
Replacement of the recBCD genes of Escherichia coli with the red recombination genes of bacteriophage lambda results in a strain in which adaptive mutation occurs at an elevated frequency. Like RecBCD-dependent adaptive mutation, Red-mediated adaptive mutation is dependent upon recA and ruvABC functions.
Poteete
Anthony R
AR
Department of Molecular Genetics & Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. anthony.poteete@umassmed.edu
Wang
Hsinju R
HR
Foster
Patricia L
PL
D000222:Adaptation, Physiological / Q000235:genetics; D010582:Bacteriophage lambda / Q000235:genetics*; D002876:Chromosomes, Bacterial; D004926:Escherichia coli / Q000235:genetics*; D007763:Lac Operon; D009154:Mutation; D011995:Recombination, Genetic; D014169:Transformation, Bacterial