Cardiovascular risk reduction in renal transplantation. Strategies for success.
One of the aims of transplantation is to restore the potential for a full life to individuals with ESRD. To obtain this strategies that allow better and longer allograft function and a reduction in adverse events that lead to premature death are required. To this end, the recommendations below showed reduce cardiovascular disease and help present and future transplant recipients live a full life. Focusing on traditional risk factors (hypertension, hyperlipidemia, discontinuation of smoking, and prevention and treatment of diabetes mellitus) in patients at risk and striving for the recommended targets will have the greatest clinical benefit. These strategies should begin in the pre-dialysis and dialysis phases in order to reduce the cumulative burden of disease. Failing this, early and hopefully pre-emptive transplantation should be the goal.
Kiberd
B A
BA
Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada. bkiberd@is.dal.ca
D001161:Arteriosclerosis / Q000453:epidemiology / Q000628:therapy; D001241:Aspirin / Q000627:therapeutic use; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D015897:Comorbidity; D003362:Cost-Benefit Analysis; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery; D006334:Heart Function Tests; D006801:Humans; D006949:Hyperlipidemias / Q000188:drug therapy / Q000453:epidemiology; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology; D017379:Hypertrophy, Left Ventricular / Q000453:epidemiology / Q000628:therapy; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000601:surgery* / Q000628:therapy; D016030:Kidney Transplantation; D008017:Life Expectancy; D016035:Pancreas Transplantation; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D015995:Prevalence; D006435:Renal Dialysis; D040242:Risk Reduction Behavior; D016540:Smoking Cessation; D016896:Treatment Outcome
D002317:Cardiovascular Agents; D007004:Hypoglycemic Agents; D000960:Hypolipidemic Agents; D007166:Immunosuppressive Agents; D001241:Aspirin