title: One gene and one outcome? No way.
abstract: The world of molecular diagnostics is undergoing major change because of both technical advances and the availability of rapidly expanding genetic databases generated by the study of human genomics. These resources comprise an extraordinary opportunity to decipher the biological importance of genetic aberrations, and link our understanding with clinical utility. The challenge lies in sorting through the information and developing effective strategies to advance molecular diagnostics.
authors.affiliation: Section on Genomic Variation, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. sc83a@nih.gov
authors.forename: Stephen
authors.initials: S
authors.lastname: Chanock
authors.forename: Sholom
authors.initials: S
authors.lastname: Wacholder
mesh_terms: D005819:Genetic Markers / Q000235:genetics; D005826:Genetics, Medical / Q000379:methods* / Q000639:trends*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods* / Q000639:trends*; D010353:Patient Education as Topic; D020641:Polymorphism, Single Nucleotide / Q000235:genetics
chemical_list: D005819:Genetic Markers