[Performance of Thallium 201 rest-redistribution spect to predict viability in recent myocardial infarction].
BACKGROUND
The detection of viability after acute myocardial infarction is primordial to select the most appropriate therapy, to decrease cardiac events and abnormal remodeling. Thallium201 SPECT is one of the radionuclide techniques used to detect viability.


OBJECTIVE
To evaluate the use of Thallium201 rest-redistribution SPECT to detect myocardial viability in reperfused patients after a recent myocardial infarction.


METHODS
Forty one patients with up to of 24 days of evolution of a myocardial infarction were studied. All had angiographically demonstrated coronary artery disease and were subjected to a successful thrombolysis, angioplasty or bypass grafting. SPECT Thallium201 images were acquired at rest and after 4 h of redistribution. These results were compared with variations in wall motion score, studied at baseline and after 3 or 4 months with echocardiography.


RESULTS
The sensitivity of rest-redistribution Thallium201 SPECT, to predict recovery of wall motion was 91% when patient analysis was performed and 79% when segmental analysis was done in the culprit region. The figures for specificity were 56 and 73% respectively.


CONCLUSIONS
Rest-distribution Thallium201 SPECT has an excellent sensitivity to predict myocardial viability in recent myocardial infarction. The data obtained in this study is similar to that reported for chronic coronary artery disease.
Coll
Claudia
C
Centro de Medicina Nuclear, Universidad de Chile, Santos Dumont 999 1E, Fono.
González
Patricio
P
Massardo
Teresa
T
Sierralta
Paulina
P
Humeres
Pamela
P
Jofré
Josefina
J
Yovanovich
Jorge
J
Aramburú
Ivonne
I
Brugère
Solange
S
Chamorro
Hernán
H
Ramírez
Alfredo
A
Kunstmann
Sonia
S
López
Héctor
H
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013794:Thallium Radioisotopes; D013997:Time Factors; D014022:Tissue Survival; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
D013794:Thallium Radioisotopes
Rendimiento del SPECT talio201 reposo-redistribución para predecir viabilidad post infarto reciente del miocardio.