title: Can clinical practice guide a research agenda?
abstract: Articles from this issue of the Bulletin indicate that clinicians are frequently adopting clinical practices that have not been supported by an evidence base. Examples of these practices are prescribing more than one antipsychotic and reserving clozapine for patients who have had multiple antipsychotic trials. This commentary suggests that these practices can be used to define important research questions.
authors.affiliation: VA Desert Pacific Mental Illness Research Education and Clinical Center, West Los Angeles VA Health Care Center, CA 90073, USA. marder@ucla.edu
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Marder
mesh_terms: D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000145:classification; D019091:Critical Pathways; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D006801:Humans; D017410:Practice Guidelines as Topic; D012106:Research; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy*; D012565:Schizophrenic Psychology
chemical_list: D014150:Antipsychotic Agents