title: Soviet experiments aimed at investigating the influence of space flight factors on the physiology of animals and man.
abstract: Results are given of biological experiments on space ship-satellites II, III, IV and V, and of scientific investigations made during the flights of Cosmonauts Gagarin and Titov aboard space ships Vostok I and Vostok II. Physiological reactions to the action of the flight stress-factors are not of a pathological character. In the post-flight period no alterations in health conditions of either cosmonauts or animals were observed. At the same time some peculiarities which were revealed while analyzing physiological reactions and a number of biological indices require further investigations. The most important tasks remaining are to study the influence of protracted weightlessness, of the biological action of space radiation, of the action of acceleration stresses after prolonged stay under zero-gravity conditions and also to analyze the influence on the organism of the whole combination of spaceflight factors, including emotional strain. In the Soviet Union, a great number of biological experiments have been conducted with a view to elucidating the action of space flight factors on living organisms and the design of systems necessary to ensure healthy activity during flight aboard rocket space vehicles. The first flight experiments with animals were conducted by means of geophysical rockets. The next step in this direction was made by the launching of Sputnik II in 1957 and by experiments on space ship-satellites in 1960-61. The main purpose of flight and laboratory investigations was to obtain the objective scientific criteria essential for ensuring the safety of manned space flight.
authors.affiliation: USSR Academy of Sciences, Moscow, USSR.
authors.forename: V V
authors.initials: VV
authors.lastname: Parin
authors.forename: O G
authors.initials: OG
authors.lastname: Gazenko
mesh_terms: D000222:Adaptation, Physiological; D000337:Aerospace Medicine; D000486:Allergy and Immunology; D000818:Animals; D001854:Bone Marrow Cells / Q000502:physiology; D002869:Chromosome Aberrations; D004285:Dogs; D004331:Drosophila melanogaster / Q000235:genetics; D005260:Female; D006339:Heart Rate; D006801:Humans; D008021:Life Support Systems; D008297:Male; D051379:Mice; D008991:Monitoring, Physiologic; D009043:Motor Activity; D063245:Plant Development; D010944:Plants / Q000235:genetics; D051381:Rats; D012119:Respiration; D012639:Seeds / Q000235:genetics / Q000254:growth & development; D013026:Space Flight / Q000295:instrumentation*; D018489:Space Motion Sickness; D014893:Weightlessness