[Effect of estrogens on the coronary circulation, cardiac contractile function, and development of reperfusion arrhythmia].
17-beta-estradiolsulfate (17-ES) was shown to exert a distinct vasoconstrictory effect on coronary vessels resulting in a decrease of the force contraction as well indexes of contractility. The distinct antiarrhythmic effect suggests that 17-ES possesses some properties of calcium antagonist.
Kobrin
V I
VI
Russian State Medical University, Russia, 117869, Moscow, 1 Ostrovitianov St.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D003326:Coronary Circulation / Q000187:drug effects*; D004958:Estradiol / Q000031:analogs & derivatives* / Q000494:pharmacology*; D008297:Male; D009200:Myocardial Contraction / Q000187:drug effects*; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control*; D010477:Perfusion / Q000009:adverse effects; D051381:Rats; D014693:Ventricular Fibrillation / Q000517:prevention & control*
D000889:Anti-Arrhythmia Agents; C048615:estradiol 17-sulfate; D004958:Estradiol
Vliianie éstrogenov na koronarnyĭ krovotok, sokratitel'nuiu funktsiiu sertdsa i razvitie reperfuzionnykh aritmiĭ.