title: [Fusafungine after tonsillectomy].
abstract: BACKGROUND
  Postoperative period after tonsillectomy is characterized by inevitable discomfort for the patient. The aim of the study was to estimate whether fusafungine in spray has an effect on healing process after the operation, especially on pain and consumption of analgesics.
  
  
  METHODS
  A prospective open, randomized study was performed on 68 patients (age 15 - 55) undergoing tonsillectomy for chronic tonsillitis. Except of standard postoperative therapy 34 patients received fusafungine in spray 4 times daily and 34 patients served as a control. Pain score in the morning and in the evening, consumption of analgesics and visual estimation of wound healing in the tonsillar fossa was evaluated.
  
  
  RESULTS
  Fusafungine in spray significantly reduces pain in the early days (2 - 4 day) after the operation and offers almost 16 % decrease in total consumption of analgesics (p < 0.04). Despite of that, total evaluation of pain score shows no significant differences in the both groups. The observation of wound healing suggests better cleanliness in 25 % of patients after fusafungine.
  
  
  CONCLUSIONS
  Fusafungine in spray improves quality of life after the tonsillectomy and so completes the spectrum of adjuvant postoperative local treatment possibilities.
authors.affiliation: HNO Abteilung VSZ Krankenhaus, Kosice-Saca, Slowakei, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Lukan
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000336:Aerosols / Q000008:administration & dosage* / Q000009:adverse effects; D000700:Analgesics / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects; D047630:Depsipeptides; D005260:Female; D005670:Fusarium; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D011182:Postoperative Care; D014068:Tonsillectomy; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000336:Aerosols; D000700:Analgesics; D000900:Anti-Bacterial Agents; D047630:Depsipeptides; C014001:fusafungin
vernacular_title: Fusafungin nach Tonsillektomie.