title: A direct comparison of noninvasive coronary angiography by electron beam tomography and navigator-echo-based magnetic resonance imaging for the detection of restenosis following coronary angioplasty.
abstract: OBJECTIVE
  To compare electron beam tomography (EBT) with MR imaging (MRI) for detection of restenosis after coronary angioplasty (PTCA).
  
  
  METHODS
  One hundred eighteen patients after PTCA were investigated. By EBT, 50 axial images were acquired (3-mm slice thickness, 120-160 mL radiographic contrast agent). MRI was performed using respiratory-gated sequences (24-48 cross-sections, 2-mm slice thickness, 20 mL Gd-DTPA). EBT and MRI images were evaluated concerning high-grade post-PTCA restenosis (> or = 70%) and validated against coronary angiography.
  
  
  RESULTS
  In EBT, 28 patients and in MRI, 31 patients were not evaluable. In the remaining patients, sensitivity for restenosis detection was 90% in EBT (17/19) and 73% in MRI (11/15; P = 0.370). In EBT, specificity was significantly higher (66% vs. 49%, P = 0.043). Overall accuracy was 71% for EBT and 53% for MRI (P = 0.014).
  
  
  CONCLUSIONS
  For the detection of high-grade restenosis after PTCA, EBT demonstrated significantly higher accuracy than MRI.
authors.affiliation: Department of Internal Medicine, Biometry, and Epidemiology, University of Erlangen-Nuernberg, Erlangen, Germany. dieter.ropers@rzmail.uni-erlangen.de
authors.forename: Dieter
authors.initials: D
authors.lastname: Ropers
authors.forename: Matthias
authors.initials: M
authors.lastname: Regenfus
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Stilianakis
authors.forename: Susanne
authors.initials: S
authors.lastname: Birke
authors.forename: Winfried
authors.initials: W
authors.lastname: Kessler
authors.forename: Werner
authors.initials: W
authors.lastname: Moshage
authors.forename: Gerhard
authors.initials: G
authors.lastname: Laub
authors.forename: Werner G
authors.initials: WG
authors.lastname: Daniel
authors.forename: Stephan
authors.initials: S
authors.lastname: Achenbach
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D003287:Contrast Media; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000175:diagnosis*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA