Specific clinical constellations might mask the genetic over-sensitivity to warfarin.
Kurnik
D
D
Loebstein
R
R
Halkin
H
H
D000483:Alleles; D000925:Anticoagulants / Q000378:metabolism* / Q000627:therapeutic use*; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism; D006333:Heart Failure / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D006720:Homozygote; D006801:Humans; D013250:Steroid Hydroxylases / Q000235:genetics* / Q000378:metabolism; D014859:Warfarin / Q000378:metabolism* / Q000627:therapeutic use*
D000925:Anticoagulants; D014859:Warfarin; D003577:Cytochrome P-450 Enzyme System; D013250:Steroid Hydroxylases