title: Reversible coma in children after improper baclofen pump insertion.
abstract: We report the occurrence of delayed postoperative coma in five of nine consecutive children following surgery for insertion of baclofen infusion pumps. We suspect that improper technique resulted in an inadvertent administration of an intrathecal baclofen bolus. We suggest ways to minimize this risk.
authors.affiliation: Department of Pediatric Anaesthesia, Neurosurgery and Oncology Montreal Childrens' Hospital, McGill University Healthcare Center, Montreal, Quebec, Canada. maria.distefano@muhc.mcgill.ca
authors.forename: Keith J
authors.initials: KJ
authors.lastname: Anderson
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Farmer
authors.forename: Karen
authors.initials: K
authors.lastname: Brown
mesh_terms: D000701:Analgesics, Opioid / Q000627:therapeutic use; D001418:Baclofen / Q000009:adverse effects*; D002547:Cerebral Palsy / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D003128:Coma / Q000188:drug therapy*; D005260:Female; D018755:GABA Agonists / Q000009:adverse effects*; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000009:adverse effects*; D007278:Injections, Spinal / Q000009:adverse effects; D008297:Male; D009020:Morphine / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy
chemical_list: D000701:Analgesics, Opioid; D018755:GABA Agonists; D009020:Morphine; D001418:Baclofen