Metal complex-substituted polysiloxanes as novel coatings for capillary electrophoresis and capillary electrochromatography.
Two novel polysiloxane-based polymers, which contain metal complexes, have been prepared. To prepare the Co(TACN)3+(2) (TACN= 1,4,7-triazacyclononane) based polymers, an orthoamide derivative of TACN was added to bromobutane-substituted methylpolysiloxane and hydrolyzed with base. Co(II) was then coordinated to the TACN, followed by cobalt oxidation to make polymer A or followed by N-octyl TACN coordination and cobalt oxidation to make polymer B. In both materials, TACN forms thermodynamically and kinetically stable Co(TACN)3+(2) complexes in which the six coordination sites of the Co(III) are occupied by nitrogens from the TACN. The polymers were coated on fused-silica capillary columns and spherical silica particles, which were used for capillary electrophoresis and capillary electrochromatography, respectively. The open and packed columns showed strong and pH-independent reversed electroosmotic flow.
Wu
Qirong
Q
Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602-5700, USA.
Lee
Milton L
ML
Harrison
Roger G
RG
D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D019075:Electrophoresis, Capillary / Q000379:methods*; D007700:Kinetics; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D012833:Siloxanes / Q000737:chemistry*; D013816:Thermodynamics
D008024:Ligands; D012833:Siloxanes