South-East Asian ovalocytosis among the population of the Highlands of Madagascar: a vestigé of the island's settlement.
In the Madagascar Highlands, 0.76% of children from 168 random primary schools, and 19 of 150 families from 3 villages, had oval-shaped erythrocytes. Most harboured the deletion in the band 3 gene characteristic of South-East Asian ovalocytosis. This genetic trait supports the Indonesian origin of the Madagascar settlement.
Rabe
T
T
Pasteur Institute of Madagascar, P.O. Box 1274, Antananarivo Zip 101, Madagascar.
Jambou
R
R
Rabarijaona
L
L
Raharimalala
L
L
Rason
M A
MA
Ariey
F
F
Dhermy
D
D
D000328:Adult; D000531:Altitude; D002648:Child; D003430:Cross-Sectional Studies; D004612:Elliptocytosis, Hereditary / Q000453:epidemiology* / Q000235:genetics; D004641:Emigration and Immigration; D017353:Gene Deletion; D006801:Humans; D008270:Madagascar / Q000453:epidemiology; D009154:Mutation / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D015995:Prevalence