Metastasectomy and active specific immunotherapy for a large single melanoma metastasis.
A patient with a large duodenal melanoma metastasis, involving adjacent jejunum and colon, is presented. Treatment consisted of a combination of radical surgery and active specific immunotherapy by means of an autologous tumor cell vaccine and BCG after which a recurrence-free survival of now more than 10 years has been observed. The role of surgery and immunotherapy in the treatment of metastatic melanoma are discussed.
Baars
A
A
Department of Medical Oncology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands. a.baars.oncol@med.vu.nl
van Riel
J M G H
JM
Cuesta
M A
MA
Jaspars
E H
EH
Pinedo
H M
HM
van den Eertwegh
A J M
AJ
D000230:Adenocarcinoma / Q000601:surgery; D000328:Adult; D001500:BCG Vaccine / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000601:surgery; D019496:Cancer Vaccines / Q000627:therapeutic use*; D004379:Duodenal Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D016233:Immunotherapy, Active; D008279:Magnetic Resonance Imaging; D008545:Melanoma / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D016609:Neoplasms, Second Primary / Q000601:surgery
D001500:BCG Vaccine; D019496:Cancer Vaccines