Correlation between oral malodor and periodontal bacteria.
Volatile sulfur compounds (VSCs), including hydrogen sulfide, methyl mercaptan, and dimethyl sulfide, are primarily responsible for oral malodor. Recently, the mgl gene encoding L-methionine-alpha-deamino-gamma-mercaptomethane-lyase, which produces methyl mercaptan, was cloned from Porphyromonas gingivalis. This article discusses the mechanism and pathogenic role of the formation of VSCs by oral bacteria.
Nakano
Yoshio
Y
Department of Preventive Dentistry, Kyushu University Faculty of Dental Science, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. yosh@dent.kyushu-u.ac.jp
Yoshimura
Mamiko
M
Koga
Toshihiko
T
D000293:Adolescent; D000328:Adult; D016866:Bacteroidaceae Infections / Q000150:complications* / Q000378:metabolism; D006209:Halitosis / Q000382:microbiology*; D006801:Humans; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology*; D016966:Porphyromonas gingivalis / Q000378:metabolism*; D013438:Sulfhydryl Compounds / Q000378:metabolism
D013438:Sulfhydryl Compounds; C005231:methylmercaptan