Solitary intraperitoneal recurrence of alpha-fetoprotein-producing gastric carcinoma: report of a case.
A solitary recurrence of gastric carcinoma in the peritoneal cavity is extremely rare. We herein present a case of solitary intraperitoneal recurrence in a patient with alpha-fetoprotein (AFP)-producing gastric carcinoma. As far as we can determine, this is the first report of such a form of recurrence in a patient with gastric carcinoma who underwent a successful resection. A review of our eight patients who had AFP-producing gastric carcinoma showed a frequent association with hepatic metastasis and a poor prognosis as has been reported previously. Our patient received intra-arterial chemotherapy with low-dose cisplatin and 5-fluorouracil to prevent hepatic recurrence, but eventually developed multiple hepatic metastases after ceasing this therapy. Therefore, adjuvant intra-arterial chemotherapy may have altered the site of first recurrence in this patient.
Wakasugi
Takehiro
T
First Department of Surgery, Nagoya City University, Medical School, Nagoya, Japan.
Akamo
Yoshimi
Y
Takeyama
Hiromitsu
H
Hasegawa
Masamitsu
M
Teranishi
Futoshi
F
Manabe
Tadao
T
D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D000368:Aged; D005260:Female; D006801:Humans; D010534:Peritoneal Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D013274:Stomach Neoplasms / Q000378:metabolism / Q000473:pathology*; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
D000509:alpha-Fetoproteins