title: New approaches to magnetic resonance imaging of intervertebral discs, tendons, ligaments, and menisci.
abstract: This review article discusses new magnetic resonance techniques for imaging collagen containing structures such as intervertebral discs, tendons, and ligaments. The semisolid collagen in tendons and ligaments is not normally demonstrable with magnetic resonance imaging but may be visualized with magic angle imaging and other techniques. This allows these structures to be studied with methods used for other tissues and organs. The ordered nature of collagen provides a directional signature for the tissues that may be of diagnostic value. Solute transport in these avascular or partially avascular structures can be observed with gadolinium chelates. The time scale of this process is much slower than for other tissues of the body. Solid state imaging techniques applied in applied in material sciences may provide other new approaches to diagnosis of disease in these structures.
authors.affiliation: Robert Steiner Magnetic Resonance Unit, MRC Clinical Sciences Centre, Imaging Sciences Department, Imperial College Faculty of Medicine, Hammersmith Hospital, London, United Kingdom. graeme.bydder@csc.mrc.ac.uk
authors.forename: Graeme M
authors.initials: GM
authors.lastname: Bydder
mesh_terms: D001692:Biological Transport; D003094:Collagen / Q000378:metabolism; D006801:Humans; D007403:Intervertebral Disc / Q000378:metabolism; D017846:Longitudinal Ligaments / Q000378:metabolism; D008159:Lumbar Vertebrae / Q000378:metabolism; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008592:Menisci, Tibial / Q000378:metabolism; D009141:Musculoskeletal System / Q000378:metabolism*; D013710:Tendons / Q000378:metabolism
chemical_list: D003094:Collagen