title: Expression pattern of cLhx2b, cZic1 and cZic3 in the developing chick diencephalon.
abstract: The diencephalon is the caudal part of the developing forebrain that gives rise to the epithalamus, thalamus, hypothalamus and retina. The mature diencephalon is functionally and anatomically parceled into well-defined nuclei. In an effort to understand how this region of the brain develops we examined the expression of several transcription factors during development. We find that the LIM homeodomain transcription factor, cLhx2b, and the zinc finger transcription factors, cZic1 and cZic3, are predominantly expressed in partially overlapping domains of the chick dorsal diencephalon. Interestingly, a correlation exists between their expression in neuroepithelial progenitor cells at early stages and in the differentiated nuclei at progressively more advanced stages of development.
authors.affiliation: Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Youngshin
authors.initials: Y
authors.lastname: Lim
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Golden
mesh_terms: D000818:Animals; D002642:Chick Embryo; D004027:Diencephalon / Q000196:embryology* / Q000378:metabolism; D005136:Eye Proteins; D015870:Gene Expression; D020869:Gene Expression Profiling; D018398:Homeodomain Proteins / Q000235:genetics*; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; D012097:Repressor Proteins; D014157:Transcription Factors / Q000235:genetics*; D016335:Zinc Fingers / Q000235:genetics*
chemical_list: D005136:Eye Proteins; D018398:Homeodomain Proteins; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; D012097:Repressor Proteins; D014157:Transcription Factors