title: Diffuse bronchiolo-alveolar carcinoma in a dog.
abstract: An eight-year-old female German wirehaired pointer was presented with signs of respiratory distress. Clinical examination, laboratory results, thoracic radiography and echocardiography indicated the presence of a diffuse interstitial lung disease with secondary appropriate erythrocytosis, pulmonary hypertension and cor pulmonale. Transthoracic fine needle aspiration biopsy of the lung suggested malignant epithelial neoplasia. A primary lung cancer with an unusually diffuse distribution of miliary/micronodular lesions was found at postmortem examination. Histological diagnosis was bronchiolo-alveolar carcinoma. Bronchiolo-alveolar carcinoma can occasionally occur in a diffuse fashion involving most or all of the lung parenchyma. In man, diffuse bronchiolo-alveolar carcinoma is considered a great imitator of other, more common diffuse interstitial forms of lung disease. This case report indicates that it is also a differential diagnosis to consider in dogs.
authors.affiliation: Pronto Soccorso Veterinario, Lodi, Italy.
authors.forename: W
authors.initials: W
authors.lastname: Bertazzolo
authors.forename: D
authors.initials: D
authors.lastname: Zuliani
authors.forename: E
authors.initials: E
authors.lastname: Pogliani
authors.forename: M
authors.initials: M
authors.lastname: Caniatti
authors.forename: C
authors.initials: C
authors.lastname: Bussadori
mesh_terms: D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000662:veterinary; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*