title: Directional coronary atherectomy: the Vienna experience.
abstract: BACKGROUND
  Several multicenter trials have shown excellent results for directional coronary atherectomy (DCA) in a selected patient cohort. To prove the applicability of this method in daily clinical routine and a nonselected patient cohort, we analyzed 46 consecutive cases performed at our catheterization lab.
  
  
  METHODS
  DCA was performed as a routine procedure in 45 suitable patients. Balloon dilatation or stent implantation postprocedure was accomplished only in case of unsatisfactory results. Quantitative coronary angiography was achieved pre- and postprocedure as well as at 6-month follow-up.
  
  
  RESULTS
  Optimal atherectomy < 20% residual stenosis was reached in 24 (52%) of 46 target lesions and a residual stenosis < 50% in 46 (100%) lesions. Procedure-related complications occurred in three (6%) patients (one major complication, death, < 24 hours, 2%; two minor complications, pseudoaneurysm, 4%). The 6-month angiographic follow-up revealed a binary restenosis rate of 29% (n = 11). Ten out of 11 restenotic lesions required revascularization. When patients were stratified in two groups according to their preprocedural minimal lumen diameter (MLD), this parameter proved to be a very strong predictor of outcome. The percentage of restenosis was significantly higher in patients with an MLD > 1.60 mm compared to patients with a smaller MLD (54% vs 19.3%; P < 0.0001). Reference vessel diameter preprocedure did not differ significantly.
  
  
  CONCLUSIONS
  Our study demonstrated that DCA is a suitable technique for the daily clinical routine, as the rates of complications and restenosis were similar to that in a highly selective patient cohort. Additionally, our study showed that patient selection should include preprocedural analysis of MLD in order to achieve optimal results. Therefore, atherectomy yielded comparable results to other conventional techniques and may be used instead of or in combination with them.
authors.affiliation: Department for Cardiology, University Clinic of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. katharina.kiss@univie.ac.at
authors.forename: K
authors.initials: K
authors.lastname: Kiss
authors.forename: M M
authors.initials: MM
authors.lastname: Hirschl
authors.forename: P
authors.initials: P
authors.lastname: Wexberg
authors.forename: A
authors.initials: A
authors.lastname: Hassan
authors.forename: G
authors.initials: G
authors.lastname: Steurer
authors.forename: D
authors.initials: D
authors.lastname: Glogar
mesh_terms: D000368:Aged; D017225:Atherectomy, Coronary; D015331:Cohort Studies; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D016896:Treatment Outcome