Regiospecific synthesis of a benanomicinone/pradimicinone analogue.
[reaction: see text] Condensation of a phenylsulfinyl naphthoate with an ortho-quinone monoketal has been used to accomplish a total synthesis of a benanomicinone/pradimicinone analogue.
Hauser
Frank M
FM
Department of Chemistry, State University of New York at Albany, Albany, New York 12222, USA. FH473@mail.albany.edu
Liao
Hongbiao
H
Sun
Yuanqiang
Y
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis*; D000935:Antifungal Agents / Q000138:chemical synthesis*; D006900:Hydroxylation; D009279:Naphthacenes / Q000138:chemical synthesis; D011809:Quinones / Q000138:chemical synthesis; D000095643:Pradimicins and Benanomicins
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; D000935:Antifungal Agents; D009279:Naphthacenes; D011809:Quinones; C108554:5,6-dihydrobenzo(a)naphthacenequinone; C466026:benanomicinone; C466025:pradimicinone; C056805:benanomicin A; D000095643:Pradimicins and Benanomicins; C058036:pradimicin A