title: Three new hydroxylated serratidine alkaloids from Huperzia serrata.
abstract: A known compound, serratidine (1), along with three hydroxylated serratidine alkaloids, 6alpha-hydroxyserrati dine (2), 4alpha-hydroxyserratidine (3) and 4alpha,6alpha-dihydroxyserratidine (4) were isolated from the CHCl3 fraction of basic materials of whole plant of the Chinese medicinal herb Huperzia serrata. The relative configurations of the above compounds were determined based on 2D NMR studies.
authors.affiliation: Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.
authors.forename: Chang-Heng
authors.initials: CH
authors.lastname: Tan
authors.forename: Xiao-Qiang
authors.initials: XQ
authors.lastname: Ma
authors.forename: Shan-Hao
authors.initials: SH
authors.lastname: Jiang
authors.forename: Da-Yuan
authors.initials: DY
authors.lastname: Zhu
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D002855:Chromatography, Thin Layer; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008516:Medicine, Chinese Traditional; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C458959:4,6-dihydroxyserratidine; C458939:4-hydroxyserratidine; C458919:6-hydroxyserratidine; D000470:Alkaloids; D004365:Drugs, Chinese Herbal; C458904:serratidine