title: Uterine leiomyosarcoma metastatic to the brain stem.
abstract: A patient with a history of an uterine leiomyosarcoma presented with diplopia, gait disturbances, and hypesthesia of the right face. MRI of the head showed a lesion located in the pons and causing obstructive hydrocephalus. Open biopsy revealed a metastatic tumor with histological features of leiomyosarcoma. Despite whole-brain irradiation, the patient died due to respiratory arrest. This case illustrates that brain stem metastasis may occur as a rare complication in uterine leiomyosarcoma.
authors.affiliation: Institute of Neuropathology, Otto-von-Guericke-University, Magdeburg, Germany. christian.mawrin@medizin.uni-magdeburg.de
authors.forename: C
authors.initials: C
authors.lastname: Mawrin
authors.forename: E
authors.initials: E
authors.lastname: Kirches
authors.forename: K
authors.initials: K
authors.lastname: Dietzmann
authors.forename: S
authors.initials: S
authors.lastname: Weis
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D001933:Brain Stem; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000473:pathology*