Demonstration of continuously seropositive population against Borna disease virus in Misaki feral horses, a Japanese strain: a four-year follow-up study from 1998 to 2001.
Borna disease virus (BDV)-specific antibodies were monitored in Misaki feral horses annually for 4 years using an electrochemiluminescence immunoassay (ECLIA). Among 130 horses examined, 35 (26.9%) with an ECLIA count above 1000 once or more were judged as BDV seropositive. Throughout the study period, p24 antibodies were more frequent than p40 antibodies in almost all positive animals. Among the 35 seropositive horses, the ECLIA count was consistently high in 12 cases. Eleven horses seroconverted from negative to positive and 7 underwent reversal. The count in the remaining 95 horses (73.1%) remained low for 4 years and these animals were judged as seronegative.
Inoue
Yoichi
Y
Department of Veterinary Teaching Hospital and Internal Medicine, Faculty of Agriculture, Miyazaki University, Gakuen-kibanadai, Japan.
Yamaguchi
Kazunari
K
Sawada
Takashi
T
Rivero
Juan C
JC
Horii
Yoichiro
Y
D000375:Aging; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis* / Q000097:blood; D001890:Borna Disease / Q000276:immunology*; D001891:Borna disease virus / Q000276:immunology*; D004563:Electrochemistry / Q000379:methods; D005260:Female; D006734:Horse Diseases / Q000276:immunology / Q000821:virology; D006736:Horses / Q000145:classification / Q000276:immunology* / Q000821:virology*; D007118:Immunoassay / Q000379:methods; D007564:Japan; D008163:Luminescent Measurements; D008297:Male; D012698:Serologic Tests; D013997:Time Factors
D000914:Antibodies, Viral