title: Terpenes from Juniperus przewalskii and their antitumor activities.
abstract: Two new diterpenes were isolated from Juniperus przewalskii, together with 17 known terpense. Their structures were elucidated by spectroscopic methods (IR, MS, 1H, 13C and 2DNMR). In addition, 3 alpha-hinokiol (3) and 3 alpha-hydroxymannol (9) exhibited effective antitumor activities to cervical carcinoma (HeLa) and human ovarian carcinoma (HO-8910) cell lines.
authors.affiliation: Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, P.R. China.
authors.forename: Wen-Shu
authors.initials: WS
authors.lastname: Wang
authors.forename: Er-Wei
authors.initials: EW
authors.lastname: Li
authors.forename: Zhong-Jian
authors.initials: ZJ
authors.lastname: Jia
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology*; D002681:China; D005260:Female; D006367:HeLa Cells; D006801:Humans; D018653:Juniperus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009904:Optical Rotation; D010051:Ovarian Neoplasms / Q000188:drug therapy; D013055:Spectrophotometry, Infrared; D013729:Terpenes / Q000302:isolation & purification* / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D013729:Terpenes