title: Epidemiology of drug resistance: the case of Staphylococcus aureus and coagulase-negative staphylococci infections.
abstract: OBJECTIVE
  To study the activity of several antibiotics against Staphylococcus spp.
  
  
  METHODS
  The study included 1209 strains of Staphylococcus spp. from two institutions; Instituto Nacional de Pediatría (National Institute of Pediatrics) and Hospital Infantil de México Federico Gómez (Mexico City Children's Hospital). Minimum Inhibitory Concentrations of all antibiotics were determined by the agar macrodilution technique and standard methods from the National Committee for Clinical Laboratory Standards.
  
  
  RESULTS
  Resistance of S. aureus was 14.2% and that of coagulase-negative staphylococci was 53.4%. The activity of different antibiotics is presented in detail.
  
  
  CONCLUSIONS
  Surveillance of strains resistant to methicillin is necessary. The English version of this paper is available too at: http://www.insp.mx/salud/index.html.
authors.affiliation: Departamento de Inmunoquímica y Biología Celular, Hospital Infantil de México Federico Gómez, Dr. Márquez No. 162, Colonia Doctores, 06720 México, D.F., México. ecalderj@yahoo.com
authors.forename: Ernesto
authors.initials: E
authors.lastname: Calderón-Jaimes
authors.forename: Luz E
authors.initials: LE
authors.lastname: Espinosa de los Monteros
authors.forename: Renata
authors.initials: R
authors.lastname: Avila-Beltrán
mesh_terms: D003030:Coagulase; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006801:Humans; D013045:Species Specificity; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013210:Staphylococcus / Q000187:drug effects* / Q000201:enzymology; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D003030:Coagulase