title: Bone remodeling analysis after placement of dental implants using polyfluorochrome sequential labeling.
abstract: Nowadays there is a general consensus related to the stability of dental implants during bone repair. The implant anchorage in the bone is very important for the stability of the element that has to support much pressure when under use. This stability is attained by bone modeling and remodeling processes. As it is known, the implant/bone interface does not present the ideal result expected by every professional. The possibility of stimulation of the bone formation at the interface and around titanium implants is based on the reaction of the bone to trauma due to the surgical procedure. This bone reaction leads to bone repair during healing. The purpose of this study is to analyze the efficiency of bone tissue labeling through polyfluorochrome sequential labeling during remodeling or neo-formation processes after the placement of smooth threaded implants used in dentistry. This work demonstrates the possibility of periodic deposition of bone identification around titanium osseointegrated implants. It was concluded that the polyfluorochrome sequential labeling is an important tool to identify bone modeling and remodeling after the insertion of titanium implants inside rabbit's tibias at different periods of time.
authors.affiliation: Department of Functional Anatomy, Structure and Ultra-Structure, Institute of Biomedical Sciences, University of São Paulo, SP, Brasil. brunokon@usp.br
authors.forename: Bruno
authors.initials: B
authors.lastname: König Júnior
authors.forename: Cláudia
authors.initials: C
authors.lastname: de Carvalho Lopes
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001846:Bone Development; D016723:Bone Remodeling / Q000502:physiology*; D003758:Dental Implantation, Endosseous / Q000379:methods*; D008297:Male; D008856:Microscopy, Fluorescence; D010012:Osteogenesis; D011817:Rabbits; D013752:Tetracycline; D013977:Tibia; D014025:Titanium; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D014025:Titanium; D013752:Tetracycline