[Collecting duct carcinoma. Personal experience and review of the literature].
OBJECTIVE
To present our experience with renal collecting duct carcinoma and review the literature.


METHODS
We reviewed our experience with collecting duct carcinoma of the kidney. We found 6 cases out of 176 nephrectomies (3.4%), which accounts for one of the largest series reported in the literature. The radiological, histological and immunohistochemical findings are analyzed.


RESULTS
The histological and immunohistochemical findings showed a specificity for high molecular weight cytokeratins and Ulex europeaeus but the imaging findings were not distinct from those of other renal tumors. According to the anatomopathological findings, we have classified the patients into three groups with three distinct courses. All patients underwent radical nephrectomy and one patient received adjuvant therapy.


CONCLUSIONS
We have identified a subgroup of low grade collecting duct carcinoma of the kidney with a particularly favorable behavior in two patients of our series. At 56 and 41 months' follow-up, both patients remain disease-free. As reported in the literature, patients with high grade and stage collecting duct carcinoma of the kidney have a poor outcome. They develop severe complications and die less than one year after the diagnosis, despite adjuvant immunotherapy.
de la Peña Zarzuelo
Enrique
E
Cátedra y Servicio de Urología, Hospital Clíniso San Carlos, Universidad Complutense, Madrid, España.
Moreno Sierra
Jesús
J
Bocardo Fajardo
Gloria
G
Redondo González
Enrique
E
Silmi Moyano
Angel
A
Aguilar Rivilla
Eva
E
Resel Estévez
Luis
L
D000368:Aged; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis*; D007685:Kidney Tubules, Collecting; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy
Carcinoma de los conductos colectores. Experiencia personal y revisión de la literatura.