Phosphonate aldehyde annulation. A one-pot synthesis of delta-hydroxy cyclopentenoic esters.
[reaction: see text] The reaction of ketone enolates with phosphonate aldehyde 2 afforded cyclopentenols 3 or keto esters 4 in a one-pot procedure.
Kraus
George A
GA
Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA. gakraus@iastate.edu
Choudhury
Prabir K
PK