Evolving role of the atopy patch test in the diagnosis of food allergy.
The atopy patch test has developed into a valuable additional tool in the diagnostic work-up of food allergy in infants and children with atopic dermatitis. A positive atopy patch test may help to prevent imposing restrictive and unnecessary diets after misjudging late reactions by clinical assessment alone. Furthermore, the combination of positive atopy patch tests together with defined levels of specific IgE makes double-blind, placebo-controlled food challenges superfluous in some cases. However, several open questions indicate the need for further studies.
Niggemann
Bodo
B
Department of Pneumology and Immunology, University Children's Hospital Charité of Humboldt University, Berlin, Germany. bodo.niggemann@charite.de
D002669:Child Welfare; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D021181:Egg Hypersensitivity / Q000175:diagnosis / Q000209:etiology; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis* / Q000209:etiology*; D007223:Infant; D007229:Infant Welfare; D016269:Milk Hypersensitivity / Q000175:diagnosis / Q000209:etiology; D010328:Patch Tests; D021183:Peanut Hypersensitivity / Q000175:diagnosis / Q000209:etiology