[Periodontal disease--an additional risk factor for cardiovascular diseases?].
In 1989, a case-control study was published, linking between coronary heart disease and periodontal disease in the studied population. Since then, a number of additional studies, focused the attention to the possible role of dental infections in the pathogenesis of atherosclerosis. Some of these newer cohort studies, are prospective in nature, measuring incidence of the two diseases in large patient populations. The present article reviews these studies, and the proposed mechanisms which might explain the relationships between these two systemically distinct diseases.
Klinger
A
A
Dept. of Periodontics, Hebrew University, Hadassah School of Dental Medicine, Jerusalem.
Goldstein
M
M
Soskolne
A
A
Klinger
I
I
Goultschin
J
J
D001161:Arteriosclerosis / Q000209:etiology; D001424:Bacterial Infections / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000209:etiology*; D016022:Case-Control Studies; D015331:Cohort Studies; D006801:Humans; D016017:Odds Ratio; D010510:Periodontal Diseases / Q000150:complications* / Q000382:microbiology; D011446:Prospective Studies; D012307:Risk Factors