title: Canine choroidal melanoma with metastases.
abstract: A 3-year-old-female, spayed Golden Retriever was examined for a unilateral retinal detachment with exophthalmos. Ultrasonographically, a mass was detected with intra- and extraocular extension. The orbit was exenterated and the dog recovered uneventfully. Histopathologic diagnosis was a primary choroidal melanoma with orbital extension, however, the behavioral and cytologic features were benign. Routine examinations postsurgically were nonremarkable. Twenty-one months after surgery the dog was euthanized for respiratory collapse with radiographic signs of metastasis. Necropsy revealed black lesions in the lung and liver. Histopathologic diagnosis was metastatic melanoma with morphology and behavior identical to the primary choroidal melanoma. This is the first definitive case of a canine choroidal melanoma with metastasis.
authors.affiliation: Animal Eye Clinic, Silver Spring, MD 20910, USA. jahyman61@yahoo.com
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Hyman
authors.forename: Seth A
authors.initials: SA
authors.lastname: Koch
authors.forename: Brian P
authors.initials: BP
authors.lastname: Wilcock
mesh_terms: D000818:Animals; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D004285:Dogs; D005260:Female; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary; D008545:Melanoma / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D014463:Ultrasonography