title: A history of prostate cancer treatment.
abstract: The increased incidence of prostate cancer has led to remarkable changes in diagnosis and treatment over the past century. What were the first ways in which prostate cancer was treated, and how did these evolve into the variety of therapeutic strategies from which patients have to choose today?
authors.affiliation: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231, USA. denmesa@jhmi.edu
authors.forename: Samuel R
authors.initials: SR
authors.lastname: Denmeade
authors.forename: John T
authors.initials: JT
authors.lastname: Isaacs
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000266:history / Q000627:therapeutic use; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008297:Male; D011468:Prostatectomy / Q000266:history; D011471:Prostatic Neoplasms / Q000266:history* / Q000628:therapy; D011878:Radiotherapy / Q000266:history; D013812:Therapeutics / Q000266:history*
chemical_list: D018931:Antineoplastic Agents, Hormonal