title: Antithrombin activity of medicinal plants from central Florida.
abstract: A chromogenic bioassay was utilized to determine the antithrombin activity of methylene chloride and methanol extracts prepared from 30 plants of central Florida. Extracts of Ardisia crenata, Tetrapanax papyriferus, Lagerstroemia indica, Callistemon lanceolatus, Antigonon Leptopus, Magnolia virginiana, and Myrica cerifera demonstrated activity of 80% or higher in this bioassay system.
authors.affiliation: Department of Chemistry, University of Central Florida, Orlando, FL 32816, USA.
authors.forename: Natalya
authors.initials: N
authors.lastname: Chistokhodova
authors.forename: Chi
authors.initials: C
authors.lastname: Nguyen
authors.forename: Tony
authors.initials: T
authors.lastname: Calvino
authors.forename: Ioulia
authors.initials: I
authors.lastname: Kachirskaia
authors.forename: Glenn
authors.initials: G
authors.lastname: Cunningham
authors.forename: D
authors.initials: D
authors.lastname: Howard Miles
mesh_terms: D005343:Fibrinolytic Agents / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D005431:Florida; D031566:Magnolia; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D010946:Plants, Medicinal; D013917:Thrombin / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D005343:Fibrinolytic Agents; D010936:Plant Extracts; D013917:Thrombin