[Generalized microsporidiosis caused by Encephalitozoon sp. in a pediatric patient with Bruton's disease].
We present the case of a four-year-old boy with a history of repeated upper respiratory tract infections and pyoderma. He presented fever, seizures, inability to talk, loss of swallowing, fine tremor in the upper extremities; positive bilateral Babinski reflex and quadriparesis. The diagnosis of Bruton's disease and generalized microporidiosis was based on immunologic analysis, smear tests with chromotrope R2 stain and indirect immunofluorescense with monoclonal 3B6 antibody for Encephalitozoon species in samples of spinal fluid, bronchial and paranasal sinus aspirates and stool, which were all positive. The patient was treated with albendazol during 72 days; he left the hospital in a good condition, walking, talking and able to swallow. His laboratory test controls were negative; he is followed up in the outpatient department.
Vásquez Tsuji
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O
Servicio Clínico de Parasitología y Micología, Instituto Nacional de Pediatría, Avenida Insurgentes Sur. No 3.700-C, Colonia, Insurgentes Cuicuilco, Código Postal 04530, Delegación Coyoacán, México, Distrito Federal.
Rodríguez Herrera
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R
Campos Rivera
T
T
Mora Tiscareño
M A
MA
Aguirre Maldonado
E
E
Yamazaki Nakashimada
M A
MA
Valencia Rojas
S
S
Martínez Barbosa
I
I
D000361:Agammaglobulinemia / Q000150:complications*; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002675:Child, Preschool; D016819:Encephalitozoon; D016890:Encephalitozoonosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male
D000981:Antiprotozoal Agents; D015766:Albendazole
Microsporidiosis generalizada por Encephalitozoon sp. en un paciente pediátrico con enfermedad de Bruton.