Botulinum toxin treatment for a compensatory hyperhidrosis subsequent to an upper thoracic sympathectomy.
BACKGROUND
Compensatory hyperhidrosis is the commonest complication of sympathectomy, but there's no known effective treatment.


METHODS
Botulinum toxin type A (a total dose of 300 MU, 1.0 MU/cm(2)) was used successfully to treat a 68-year-old male with a 5-year history of compensatory hyperhidrosis of the anterior chest following thoracic sympathectomy for palmar hyperhidrosis.


RESULTS
The hyperhidrosis resolved for 8 months without systemic side effects.


CONCLUSIONS
Intracutaneous injection of botulinum toxin is a fast, safe, effective and well-accepted approach for treatment of compensatory hyperhidrosis.
Huh
C H
CH
Department of Dermatology, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.
Han
K H
KH
Seo
K I
KI
Eun
H C
HC
D000109:Acetylcholine / Q000037:antagonists & inhibitors; D000368:Aged; D001905:Botulinum Toxins / Q000627:therapeutic use*; D002799:Cholinergic Fibers / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D013545:Sweat Glands / Q000294:innervation; D013562:Sympathectomy; D013909:Thorax / Q000294:innervation
D001905:Botulinum Toxins; D000109:Acetylcholine