A comparison of the cytologic and histologic features of meningiomas in four dogs.
The cytologic and histologic features of 2 intracranial and 2 spinal (extramedullary cervical) canine meningiomas were compared. Cerebrospinal fluid analysis in 2 cases revealed mild, mixed cell pleocytosis, primarily composed of small lymphocytes and monocytoid cells, with a moderate increase in total protein concentration. Cytologic features suggestive of meningioma included cells with both epithelial and mesenchymal characteristics and a tendency towards cell clustering. Tumor location also was useful in making a diagnosis. The 4 meningiomas differed histologically from one another, and included angioblastic, psammomatous, meningotheliomatous, and microcystic anaplastic types, which conformed to a classification scheme for human meningiomas. The classification scheme could not be applied to cytologic specimens.
Zimmerman
Kurt L
KL
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, VA 24061, USA. kzimmerm@vt.edu
Bender
Holly S.
HS
Boon
G. Daniel
GD
Prater
M. Renee
MR
Thorn
Catherine E.
CE
Prater
Don
D
Robertson
John L.
JL
Saunders
Geoffrey K.
GK
Sponenberg
D. Phillip
DP
Inzana
Karen D.
KD
Lanz
Otto I.
OI
Wright
Eric
E