Cervical implant from villoglandular endometrial adenocarcinoma masquerading as cervical villoglandular adenocarcinoma.
This is an unusual presentation of a rare subtype of endometrial adenocarcinoma (villoglandular papillary carcinoma, VGPC) in a 71-year-old woman, which was initially diagnosed on cervical biopsy as being primary cervical VGPC. Loop excision failed to show any evidence of residual disease. Subsequent hysterectomy revealed a localized villoglandular carcinoma involving the uterine fundus and invading the inner one-third of the myometrium, the background endometrium was atrophic. The remaining cervix contained a focus of papillary forming endometrial type adenocarcinoma involving the surface epithelium and the superficial subepithelial glands. In conclusion, VGPC of cervix occurs mainly in young women and can be treated conservatively, pathologists should be cautious in making such a diagnosis in a postmenopausal woman before ruling out a primary endometrial origin.
Al-Nafussi
A
A
Department of Pathology, Medical School Building, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK. AAN@srv4.med.ed.ac.uk
Obafunwa
J
J
Jordan
L B
LB
Fulton
I
I
Martin
C
C
Beattie
G
G
D000231:Adenocarcinoma, Papillary / Q000175:diagnosis* / Q000601:surgery; D000368:Aged; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000601:surgery; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009361:Neoplasm Invasiveness; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000601:surgery