title: [Hepatitis C virus RNA in patients with chronic hepatitis C].
abstract: Reviews recent data on the detection of genome and replicative HCV RNA in patients with chronic hepatitis C by PCR and in situ hybridization. Discusses the results of HCV RNA detection in the liver, lymphocytes, serum, and other organs and tissues and notes the relationship between the incidence of RNA and activity of the pathological process. Analyzes the results of HCV RNA detection after IFN treatment. Discusses the role of HCV RNA in the pathogenesis of hepatitis C.
authors.forename: E I
authors.initials: EI
authors.lastname: Lakina
authors.forename: A A
authors.initials: AA
authors.lastname: Kushch
mesh_terms: D018450:Disease Progression; D016174:Hepacivirus / Q000235:genetics / Q000302:isolation & purification*; D019698:Hepatitis C, Chronic / Q000097:blood / Q000503:physiopathology / Q000628:therapy / Q000821:virology*; D006801:Humans; D017403:In Situ Hybridization; D007372:Interferons / Q000627:therapeutic use; D008099:Liver / Q000821:virology; D008214:Lymphocytes / Q000821:virology; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000032:analysis* / Q000097:blood; D014779:Virus Replication
chemical_list: D012367:RNA, Viral; D007372:Interferons
vernacular_title: RNK virusa gepatita C v organizme bol'nykh khronicheskim gepatitom C.