Tumoricidal effect of macrophages on transplantable melanoma cells with regard to their sensitivity to exogenous cytokines.
We studied the correlation between the cytotoxic effect of hamster peritoneal macrophages from animals bearing transplantable melanomas of common origin but differing in many biological features on the cells of those melanomas and the sensitivity of the melanoma cells to exogenous OSM, TNF-alpha and IL6. Our results did not show such a correlation.
Cichorek
M
M
cichorek@amedec.amg.gda.pl
Zarzeczna
M
M
Kozłowska
K
K
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D006224:Cricetinae; D016207:Cytokines / Q000494:pharmacology*; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D008264:Macrophages / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008546:Melanoma, Experimental / Q000276:immunology* / Q000473:pathology; D008647:Mesocricetus; D053683:Oncostatin M; D010455:Peptides / Q000494:pharmacology; D012867:Skin / Q000473:pathology; D013778:Tetrazolium Salts; D013844:Thiazoles
D000970:Antineoplastic Agents; D016207:Cytokines; D010455:Peptides; D013778:Tetrazolium Salts; D013844:Thiazoles; D053683:Oncostatin M; C022616:thiazolyl blue