Ethical and legal issues in xenotransplantation.
In most western countries, there is a 'human organ shortage' with waiting lists for the performance of transplantation. In a recent report of the UNOS Ethics Committee it is stated that there are approximately 31,000 potential recipients on waiting lists, but only one fourth of potential donors give their specific consent. Xenotransplantation--defined as the transplantation of animal cells, tissues or organs into human beings--is associated with particular ethical dilemmas, namely the problems of efficiency and safety of this medical procedure. The objective of this study is to analyse the ethical dilemmas in xenotransplantation with the background of a personal view of moral life. Also, xenotransplantation will be evaluated as far as the legal regulation of transplantation is concerned. In particular, we will consider patients rights in accordance with existing laws on organ and tissue transplantation, animal research and clinical trials.
Melo
H
H
Estrada da Cicunvalacao, 9925, Porto 4250-150, Portugal. ruinunes@med.up.pt
Brandao
C
C
Rego
G
G
Nunes
R
R
D032761:Animal Experimentation; D000827:Animal Welfare; D000818:Animals; D030801:Animals, Genetically Modified; D002986:Clinical Trials as Topic; D006801:Humans; D007258:Informed Consent; D038622:Internationality; D018579:Patient Selection; D019724:Presumed Consent; D040841:Resource Allocation; D012926:Social Control, Formal; D014019:Tissue Donors; D014183:Transplantation, Heterologous