title: Immunohistochemical colocalization of Yellow and male-specific Fruitless in Drosophila melanogaster neuroblasts.
abstract: The Drosophila melanogaster fruitless gene encodes multiple male-specific transcription factors that are hypothesized to regulate a hierarchy of genes responsible for the development of male courtship behavior. Here we show that there are dramatically increased levels of the protein product of the male courtship behavior gene yellow associated with male-specific Fruitless protein in a subset of neuroblasts in third-instar larval male brains. We hypothesize that yellow is downstream of fruitless in a male courtship behavior developmental genetic pathway.
authors.affiliation: Department of Developmental and Cell Biology, University of California, Irvine, CA, USA
authors.forename: Anna
authors.initials: A
authors.lastname: Radovic
authors.forename: Patricia J
authors.initials: PJ
authors.lastname: Wittkopp
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Long
authors.forename: Mark David
authors.initials: MD
authors.lastname: Drapeau
mesh_terms: D000818:Animals; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000378:metabolism*; D005260:Female; D007150:Immunohistochemistry; D019476:Insect Proteins / Q000096:biosynthesis*; D008297:Male; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009474:Neurons / Q000378:metabolism*; D012737:Sex Factors; D012726:Sexual Behavior, Animal; D014157:Transcription Factors / Q000096:biosynthesis*; D014158:Transcription, Genetic
chemical_list: D029721:Drosophila Proteins; D019476:Insect Proteins; D009419:Nerve Tissue Proteins; D014157:Transcription Factors; C103226:fru protein, Drosophila; C050680:y protein, Drosophila