title: Bio- and chemo-informatics beyond data management: crucial challenges and future opportunities.
abstract: Bio- and chemo-informatics are now thought to be crucial to the success and integration of biotechnology and drug discovery. Research in this area has expanded to go beyond data- and information-management. Here, we review exemplary areas, such as target identification and validation, virtual screening, and prediction of downstream characteristics of leads, where further research will play a key role in progressing the field.
authors.affiliation: Albany Molecular Research, Bothell Research Center, (AMRI-BRC), 18804 North Creek Parkway, Bothell, WA 98011, USA.
authors.forename: Florence L
authors.initials: FL
authors.lastname: Stahura
authors.forename: Jürgen
authors.initials: J
authors.lastname: Bajorath
mesh_terms: D001709:Biotechnology; D019295:Computational Biology / Q000379:methods*; D055808:Drug Discovery; D001330:Electronic Data Processing / Q000379:methods*; D005544:Forecasting; D006801:Humans; D048088:Informatics / Q000379:methods*; D019451:Information Management / Q000379:methods*