Community-based dietary phytate reduction and its effect on iron status in Malawian children.
This study describes a community-based method used in rural Malawi to remove dietary phytate, an inhibitor of iron absorption, and notes an improvement in the iron status of ten children who participated in the trial. Phytate was removed by soaking maize flour in excess water with phytase and decanting the water before cooking the flour. Iron status, as measured by soluble transferrin receptor and zinc protoporphyrin, was improved but not normal.
Manary
Mark J
MJ
Department of Pediatrics, Washington University School of Medicine, St Louis Children's Hospital, One Children's Place, St Louis, MO 63110, USA. manary@kids.wustl.edu
Krebs
Nancy F
NF
Gibson
Rosalind S
RS
Broadhead
Robin L
RL
Hambidge
K Michael
KM
D001682:Biological Availability; D002664:Child Nutritional Physiological Phenomena; D002675:Child, Preschool; D003906:Developing Countries; D004032:Diet; D005260:Female; D005511:Food Handling / Q000379:methods; D006801:Humans; D007501:Iron / Q000493:pharmacokinetics*; D008295:Malawi; D008297:Male; D010833:Phytic Acid / Q000008:administration & dosage*; D012423:Rural Health
D010833:Phytic Acid; D007501:Iron