[Outbreak of human rotavirus infection in an adult community].
BACKGROUND
Group A rotaviruses are known as the major cause of severe dehydrating diarrhoea in infants.


OBJECTIVE
In adults, the rotavirus infections are usually asymptomatic. In the present study the authors report a group A rotavirus outbreak in a psychiatric nursing home for adults.


RESULTS
The outbreak lasted 3 weeks; the attack rate was 20%. The mean age of patients was 39 y (range 21 to 65; n = 25). The symptoms were mild, and most of the patients recovered within 2 or 3 days. The epidemiological data suggested that the virus was introduced by a patient, and it was transmitted by person-to-person route. Rotavirus positive specimens were characterised by serotyping and electropherotyping. The serotype-specific monoclonal antibody immunoassay demonstrated the circulation of a common strain with G1 specificity. These samples shared identical genome profile with strains circulated in the paediatric communities of the country.


CONCLUSIONS
In Hungary, this is the first published gastroenteritis outbreak among adults caused by group A rotaviruses with G1 serotype specificity.
Bányai
Krisztián
K
Regionális Virológiai Laboratóríum, Allami Népegészségügyi és Tisztiorvosi Szolgálat Baranya Megyei Intézete, Pécs.
Angyal
Márta
M
Körmendi
Eva
E
Lakatos
Ferenc
F
Uj
Mária
M
Szücs
György
G
D000328:Adult; D000911:Antibodies, Monoclonal; D003937:Diagnosis, Differential; D004196:Disease Outbreaks; D005260:Female; D005759:Gastroenteritis / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology*; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007118:Immunoassay / Q000379:methods; D008297:Male; D001523:Mental Disorders / Q000150:complications; D008875:Middle Aged; D009735:Nursing Homes / Q000706:statistics & numerical data; D012401:Rotavirus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D012703:Serotyping
D000911:Antibodies, Monoclonal
Humán rotavírusjárvány felnótt közösségben.