[Evaluation of cardiac load by measuring brain natriuretic peptide after thoracic esophagectomy and gastric tube in place].
A small dose of dopamine has been routinely infused for hemodynamic stabilization and diuresis in patients undergoing esophagectomy and gastric tube in place until the seventh postoperative day in our hospital. The timing of discontinuing infusion of dopamine was determined by our experience. However, there was no rationale to determine the timing of discontinuing it. Therefore, eight patients with ASA physical status I or II, undergoing esophagectomy and gastric tube in place were studied to evaluate postoperative cardiac load using brain natriuretic peptide, which is a biochemical detector of left ventricular dysfunction. There were no hemodynamic and cardiac events including myocardial ischemia and infarction in any patients. The postoperative course was uneventful in all patients. Serum BNP increased gradually and significantly until the third postoperative day with increasing urine volume. Serum BNP returned to the baseline level on the fourth postoperative day. However, serum BNP was still high in 3 patients on the sixth postoperative day in spite of dopamine. We conclude that cardiac overload was recognized until the third postoperative day.
Kishi
Yoshihiko
Y
Department of Anesthesiology, Osaka Medical Center of Cancer and Cardiovascular Diseases, Osaka 537-8511.
Yamasaki
Kyouko
K
Taniguchi
Hiroshi
H
Nakagawa
Masashi
M
Kita
Takashi
T
Manmoto
Tadanori
T
Kanbara
Noriko
N
Sakai
Toshiko
T
Kabuto
Toshiyuki
T
D000368:Aged; D016629:Esophagectomy; D004944:Esophagoplasty; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007441:Intubation, Gastrointestinal; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D011184:Postoperative Period
D020097:Natriuretic Peptide, Brain