title: Meniscal transplantation.
abstract: The aims of a meniscal replacement are: 1) to reduce the pain experienced by some patients following meniscus resection; 2) to prevent the degenerative changes of cartilage and the changes in subchondral bone following meniscus resection; 3) to avoid or reduce the risk of osteoarthritis following meniscus resection; 4) to restore optimally the mechanical properties of the knee joint after meniscal resection. The results of meniscus transplantation have been studied in animals. There is no proof from these experiments that replacement of a meniscus can reduce the risk of arthritis, but there are indications that it can decrease the development of cartilage degeneration. In humans, the results of meniscus transplantation have been reported in several series of patients, operated with different techniques. There are no controlled studies of meniscus replacement in humans. In case of meniscal allograft implantation surgery should be minimally invasive, not sacrificing the original meniscal insertion points. It appears preferable to use an open technique in medial transplantation, whereas the arthroscopic approach appears to allow for easier lateral implantation.
authors.affiliation: Department of Orthopedic Surgery, Physical Medicine and Rehabilitation, Ghent University Hospital, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Verdonk
mesh_terms: D000818:Animals; D001182:Arthroscopy / Q000379:methods; D001696:Biomechanical Phenomena; D002356:Cartilage / Q000473:pathology*; D004195:Disease Models, Animal; D006801:Humans; D007719:Knee Joint / Q000473:pathology / Q000601:surgery*; D008592:Menisci, Tibial / Q000473:pathology / Q000601:surgery / Q000637:transplantation*; D010003:Osteoarthritis / Q000517:prevention & control; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D014184:Transplantation, Homologous; D016896:Treatment Outcome