Cloning and molecular characterization of the cDNA encoding histone H1 from Leishmania braziliensis.
The isolation and molecular characterization of the histone H1-encoding gene from Leishmania braziliensis was carried out. The gene is present in the genome as a single copy and transcribed as a polyadenylated transcript of 830 nucleotides. The deduced amino acid sequence has in its central region the DNA binding K-[K/R]-A-A-[A/P] motif, which is repeated in tandem 9 times.
Martínez
E
E
Departamento de Parasitología, Ecología y Genética, Facultad de Farmacia, Universidad de La Laguna, Tenerife, Spain.
Thomas
M C
MC
Alonso
V
V
Carmelo
E
E
González
A C
AC
Del Castillo
A
A
Valladares
B
B
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular / Q000379:methods*; D018076:DNA, Complementary / Q000235:genetics; D016054:DNA, Protozoan / Q000032:analysis / Q000235:genetics; D006657:Histones / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D007892:Leishmania braziliensis / Q000235:genetics*; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
D018076:DNA, Complementary; D016054:DNA, Protozoan; D006657:Histones