title: Familial Mediterranean fever in 2 Japanese families.
abstract: We describe 3 Japanese patients in 2 families with familial Mediterranean fever (FMF) as determined by gene analysis. FMF is an ethnically related, genetic disease, occurring commonly in some Mediterranean populations. The FMF gene (MEFV) mutation found in our patients is M694I. The patients may be remote from East Asian extraction.
authors.affiliation: Department of Pediatrics, Graduate School of Medicine, Shinshu University, Matsumoto, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Shinozaki
authors.forename: Kazunaga
authors.initials: K
authors.lastname: Agematsu
authors.forename: Kozo
authors.initials: K
authors.lastname: Yasui
authors.forename: Haruo
authors.initials: H
authors.lastname: Nagumo
authors.forename: Hajime
authors.initials: H
authors.lastname: Naitoh
authors.forename: Kuniaki
authors.initials: K
authors.lastname: Naganuma
authors.forename: Atsushi
authors.initials: A
authors.lastname: Komiyama
mesh_terms: D000293:Adolescent; D000328:Adult; D004252:DNA Mutational Analysis; D010505:Familial Mediterranean Fever / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D007564:Japan; D020125:Mutation, Missense; D010375:Pedigree; D017354:Point Mutation