title: Animal genetic manipulation--a utilitarian response.
abstract: I examine the process and outcomes of animal genetic manipulation ('transgenesis') with reference to its morally salient features. I consider several objections to transgenesis. I examine and reject the alleged intrinsic wrongness of 'deliberate genetic sequence alteration,' as I do the notion that transgenesis may lead to human genetic manipulation. I examine the alleged wrongness of killing inherent in transgenesis, and suggest that the concept of 'replaceability' successfully justifies such killing, although not for entities deemed to possess 'personhood.' I examine 'significant suffering' associated with transgenesis and propose the radical conclusion that, although it would be wrong to prohibit animal genetic manipulation per se, utilitarians ought to support a 'default prohibition' on transgenic experiments that entail significant suffering.
authors.affiliation: School of Science & Engineering, Division of Molecular & Life Sciences, University of Abertay Dundee, Kydd Building, Bell Street, Dundee, Scotland DD1 1HG. mltkrs@tay.ac.uk
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Smith
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D026689:Ethical Analysis; D005818:Genetic Engineering / Q000379:methods; D012926:Social Control, Formal; D013315:Stress, Psychological; D035761:Wedge Argument