title: Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice.
abstract: A high-molecular-weight constituent of cranberry juice has been found to inhibit the sialyllactose specific adhesion of Helicobacter pylori strains to immobilized human mucus, erythrocytes, and cultured gastric epithelial cells. Different isolates of H. pylori differ in their affinity to the cranberry juice constituent. Cranberry juice may also inhibit adhesion of bacteria to the stomach in vivo, and may prove useful for the prevention of stomach ulcer that is caused by H. pylori.
authors.affiliation: Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors.forename: Ora
authors.initials: O
authors.lastname: Burger
authors.forename: Ervin
authors.initials: E
authors.lastname: Weiss
authors.forename: Nathan
authors.initials: N
authors.lastname: Sharon
authors.forename: Mina
authors.initials: M
authors.lastname: Tabak
authors.forename: Ishak
authors.initials: I
authors.lastname: Neeman
authors.forename: Itzhak
authors.initials: I
authors.lastname: Ofek
mesh_terms: D001422:Bacterial Adhesion / Q000187:drug effects*; D001628:Beverages; D002478:Cells, Cultured / Q000382:microbiology; D004912:Erythrocytes / Q000382:microbiology; D005753:Gastric Mucosa / Q000382:microbiology*; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D016480:Helicobacter pylori / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008970:Molecular Weight; D008517:Phytotherapy; D013276:Stomach Ulcer / Q000517:prevention & control; D029799:Vaccinium macrocarpon / Q000737:chemistry*