Fringe phenotypes in autism: a review of clinical, biochemical and cognitive studies.
Progress in identifying the genetic vulnerability factors in autism requires correct identification of the inherited phenotype(s). This can be achieved not only by the accurate description of the affected subject but also by the identification of vulnerability traits in non-affected relatives of autistic probands. This review will focus on this last strategy and principally on clinical, biochemical and cognitive traits.
Goussé
Véronique
V
Consultation autisme, service de psychopathologie de l'enfant et de l'adolescent, hôpital Robert Debré, assistance publique-hôpitaux de Paris, 75019, Paris, France.
Plumet
Marie Hélène
MH
Chabane
Nadia
N
Mouren-Siméoni
Marie-Christine
MC
Ferradian
Nathalie
N
Leboyer
Marion
M
D001321:Autistic Disorder / Q000150:complications* / Q000235:genetics* / Q000378:metabolism; D003072:Cognition Disorders / Q000209:etiology*; D003147:Communication Disorders / Q000209:etiology; D020022:Genetic Predisposition to Disease; D006801:Humans; D010641:Phenotype; D012701:Serotonin / Q000378:metabolism; D012920:Social Behavior Disorders / Q000209:etiology; D019956:Stereotypic Movement Disorder / Q000209:etiology
D012701:Serotonin