DNA binding and bending to initiate packaging of phage lambda DNA.
Physical and genetic studies verify that the DNA binding domain of protein gpNu1 (which initiates packaging of phage lambda DNA) is a winged helix-turn-helix (w HTH) and that gpNu1 dimers bind sites that are brought close through DNA bending.
Campbell
Allan
A
Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA.
D010582:Bacteriophage lambda / Q000235:genetics*; D004279:DNA, Viral / Q000378:metabolism*; D019077:Helix-Turn-Helix Motifs; D009690:Nucleic Acid Conformation; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism
D004279:DNA, Viral; D014764:Viral Proteins; C050856:lambda phage protein Nu 1