title: Achieving adherence with antiretroviral medications for pediatric HIV disease.
abstract: Factors influencing antiretroviral adherence for 42 HIV-positive children were elicited from primary caregivers, and the perspectives of families and clinicians regarding success with adherence were compared. Interviews in preferred language (Spanish or English), chart reviews, and visual analogue scales (VAS) were used. Adherence was high by traditional markers of prescriptions filled (100%), doses reported taken (97%), and appointments kept (88%). Clinicians estimated slightly but not significantly lower adherence than did families using the VAS. Sixty-four percent of families reported barriers to adherence, and 30% reported strategies that differ from those in the general adherence literature. Adherence strategies devised by families depended heavily on family support and resolution of disclosure issues in the household.
authors.affiliation: Columbia University School of Nursing, New York, USA.
authors.forename: Mary
authors.initials: M
authors.lastname: Byrne
authors.forename: Judy
authors.initials: J
authors.lastname: Honig
authors.forename: Andrea
authors.initials: A
authors.lastname: Jurgrau
authors.forename: Susan M
authors.initials: SM
authors.lastname: Heffernan
authors.forename: Marie Collins
authors.initials: MC
authors.lastname: Donahue
mesh_terms: D000293:Adolescent; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D017028:Caregivers / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D005006:Ethnicity; D005191:Family Characteristics; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D007223:Infant; D007407:Interviews as Topic; D010349:Patient Compliance / Q000523:psychology*
chemical_list: D019380:Anti-HIV Agents