title: Batch control system project for a pharmaceutical plant.
abstract: This paper describes a case study of a control system design for a batch pharmaceutical process. The ISA standard S88.01 batch control models and terminology were used as the main guidelines for the implementation. As the S88 is not a guide for how to apply the definitions/structures, etc., one of the main goals of our work was to create a methodology for decomposition of functional requirements in terms of S88 models and structures. This methodology was tested on a real problem, described in the case study. Also presented are some remarks on project methodology and Food and Drug Administration validation.
authors.affiliation: Department of Computing and Control Engineering, Faculty of Chemical Engineering, Prague Institute of Chemical Technology, Praha, Czech Republic.
authors.forename: Roman
authors.initials: R
authors.lastname: Holý
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Pozivil
mesh_terms: D017076:Computer-Aided Design; D003460:Crystallization; D018153:Czech Republic; D005246:Feedback; D005374:Filtration / Q000379:methods; D008962:Models, Theoretical; D009761:Nystatin / Q000302:isolation & purification; D011786:Quality Control; D012984:Software; D013678:Technology, Pharmaceutical / Q000295:instrumentation / Q000379:methods* / Q000592:standards*
chemical_list: D009761:Nystatin