Brugada-like electrocardiographic pattern induced by fever.
The Brugada syndrome is characterized by a peculiar ST-segment elevation in the right precordial leads and the propensity to develop ventricular arrhythmias. Mutations in a cardiac sodium channel gene have been linked to this syndrome and some experimental data suggest that the dysfunction of the mutated channel can be temperature sensitive. This report describes a patient in whom a typical Brugada ECG pattern developed in relation to fever but could not be reproduced at normal temperature on administration offlecainide. This case suggests that in some patients a Brugada-like ECG may only manifest during a febrile state.
Saura
Daniel
D
Department of Cardiology, University Hospital Virgen de la Arrixaca, Murcia, Spain. danielsaura@wanadoo.es
García-Alberola
Arcadi
A
Carrillo
Pilar
P
Pascual
Domingo
D
Martínez-Sánchez
Juan
J
Valdés
Mariano
M
D000368:Aged; D002037:Bundle-Branch Block / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005334:Fever / Q000150:complications*; D006801:Humans; D008297:Male