[Pulse oximetry screening for sleep-disordered breathing in stroke].
BACKGROUND
The prevalence of sleep-disordered breathing, particularly obstructive sleep apnea, among stroke patients is high. Routine screening with the current diagnostic gold standard of polysomnography is not feasible. Pulse oximetry could be a simple screening test.


METHODS
The signal of pulse oximetry, recorded during full polysomnography in 184 stroke patients during neurological rehabilitation, was analyzed automatically by software for desaturations >/= 4 %. The polysomnographic apnoea-hypopnoea-index (AHI) was used as the diagnostic gold standard and compared with the oxygen desaturation index (ODI).


RESULTS
Correlation between AHI of PSG and ODI of oximetry was r = 0.84 (p < 0.001). Dependent on the definition of SDB (AHI 10, 15, 20 or 30/h) and the cut-off-point for the ODI (e. g. 15/h) sensitivity was 32 - 83 % and specificity 99 - 96 %. The diagnostic accuracy as determined by the area under the ROC-curve was 96 %.


CONCLUSIONS
Automated analysis of pulse oximetry gives reasonable results for screening for SDB in stroke patients and could be used in populations with high pre-test probability.
Wessendorf
T E
TE
Ruhrlandklinik, Abt. Pneumologie/Schlaf- und Beatmungsmedizin, Essen, Germany. thomas.wessendorf@uni-essen.de
Alymov
G
G
Wang
Y M
YM
Stampa
J
J
Thilmann
A F
AF
Teschler
H
H
D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000097:blood*; D017286:Polysomnography; D012372:ROC Curve; D012044:Regression Analysis; D012120:Respiration Disorders / Q000097:blood / Q000175:diagnosis*; D012893:Sleep Wake Disorders / Q000097:blood / Q000175:diagnosis*; D020521:Stroke / Q000097:blood / Q000150:complications* / Q000503:physiopathology*
D010100:Oxygen
Pulsoximetrie als Schlafapnoescreening bei Schlaganfallpatienten.