title: Effectiveness of a pharmacist-based smoking-cessation program and its impact on quality of life.
abstract: We conducted a prospective, open-label trial to evaluate the effectiveness of a pharmacist-based, comprehensive, smoking-cessation program with 31 self-referred subjects. A secondary goal was to measure changes in health-related quality of life (HRQOL) during the cessation attempt. The program consisted of weekly, 1-hour group sessions over 12 weeks. It incorporated nicotine replacement therapy (patch, gum) with extensive behavior modification counseling. Trained pharmacists served as program facilitators. Smoking cessation was chemically verified at 3 and 6 months by exhaled carbon monoxide. The patients' HRQOL was measured using the smoking-cessation quality of life questionnaire at baseline, 2 weeks, and 1, 2, 3, and 6 months. Chemically verified abstinence rates at 3 and 6 months were 42% (13 patients) and 26% (8 patients), respectively. Among patients who quit, vitality, mental health, and self-control significantly improved during the 3-month program. Six-month cessation rates were modest, although HRQOL improved within 3 months of abstinence.
authors.affiliation: Division of Clinical and Administrative Pharmacy, University of Iowa College of Pharmacy, Iowa City 52241, USA. alan-zillich@uiowa.edu
authors.forename: Alan J
authors.initials: AJ
authors.lastname: Zillich
authors.forename: Melody
authors.initials: M
authors.lastname: Ryan
authors.forename: Aimee
authors.initials: A
authors.lastname: Adams
authors.forename: Bryan
authors.initials: B
authors.lastname: Yeager
authors.forename: Karen
authors.initials: K
authors.lastname: Farris
mesh_terms: D000287:Administration, Topical; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009538:Nicotine / Q000008:administration & dosage / Q000627:therapeutic use; D018722:Nicotinic Agonists / Q000008:administration & dosage / Q000627:therapeutic use; D010595:Pharmacists; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D016540:Smoking Cessation / Q000379:methods* / Q000523:psychology; D013375:Substance Withdrawal Syndrome / Q000517:prevention & control
chemical_list: D018722:Nicotinic Agonists; D009538:Nicotine