title: Histopathologic findings in human cerebral aneurysms embolized with platinum coils: report of two cases and review of the literature.
abstract: This report describes 2-week and 20-month histopathologic findings in small aneurysms embolized with platinum coils. Electron microscopy showed the presence of endothelial cells encroaching on the platinum coils at the orifice of the aneurysm in both cases. We confirm that endothelial growth can be induced as early as 2 weeks after embolization of small human aneurysms with platinum coils, similar to previous observations in animal models and human cases.
authors.affiliation: Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan.
authors.forename: Shoichiro
authors.initials: S
authors.lastname: Ishihara
authors.forename: Michel E
authors.initials: ME
authors.lastname: Mawad
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ogata
authors.forename: Chihiro
authors.initials: C
authors.lastname: Suzuki
authors.forename: Nobusuke
authors.initials: N
authors.lastname: Tsuzuki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Katoh
authors.forename: Akira
authors.initials: A
authors.lastname: Ohnuki
authors.forename: Takahito
authors.initials: T
authors.lastname: Miyazawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nawashiro
authors.forename: Tatsumi
authors.initials: T
authors.lastname: Kaji
authors.forename: Katsuji
authors.initials: K
authors.lastname: Shima
mesh_terms: D000368:Aged; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010984:Platinum
chemical_list: D010984:Platinum