[Clinical recurrence of Cushing syndrome without evidence of tumor recurrence: radical hypophysectomy?].
Outcome following radiation therapy for hormonally-active Cushing adenoma is reported. Conventional radiation using 20 to 30 grays improved mass and hormone level in 30 to 80% of the patient. Gamma-knife radiosurgery was at least as effective. These results are discussed in this review.
Estour
B
B
Service d'Endocrinologie, Hôpital Bllevue, CHU de Saint-Etienne, 42055 Saint-Etienne Cedex, France. bruno.estour@chu-st-etienne.fr
Duthel
R
R
Mounier
Ch
Ch
D000236:Adenoma / Q000150:complications / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003480:Cushing Syndrome / Q000209:etiology / Q000601:surgery*; D003952:Diagnostic Imaging; D006801:Humans; D007016:Hypophysectomy / Q000379:methods*; D007018:Hypopituitarism / Q000209:etiology; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D018365:Neoplasm, Residual; D010910:Pituitary Irradiation / Q000009:adverse effects; D010911:Pituitary Neoplasms / Q000150:complications / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D016634:Radiosurgery / Q000009:adverse effects; D012074:Remission Induction; D012086:Reoperation; D016896:Treatment Outcome
Les récurrences cliniques de la maladie de Cushing sans récidive tumorale documentée: hypophysectomie radique.