[ABO-incompatible liver transplantation and patients with hepatopulmonary syndrome].
From 1991 to 2000, more than 100 ABO-incompatible liver transplantations were performed in 12 institution in Japan. The overall survival rate is 60%. Survival data appear to have improved in these years even in adult cases, although acute vascular rejection causing hepatic necrosis, infection, and intrahepatic bile duct injury are major complications to be resolved. Hepatopulmonary syndrome (HPS) was considered to be a contraindication to transplantation in the 1980s. However, even severe cases can recover from hypoxia after liver transplantation, and improved survival data were reported in the 1990s. Intensive respiratory therapy after transplantation with NO inhalation allows expansion of the indications for transplantation in HPS.
Koyamada
Nozomi
N
Division of Advanced Surgical Science and Technology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Satomi
Susumu
S
D000017:ABO Blood-Group System; D000293:Adolescent; D001787:Blood Group Incompatibility; D002648:Child; D002675:Child, Preschool; D005260:Female; D020065:Hepatopulmonary Syndrome / Q000601:surgery*; D006801:Humans; D007223:Infant; D016031:Liver Transplantation / Q000401:mortality / Q000706:statistics & numerical data; D008297:Male; D019990:Perioperative Care; D015996:Survival Rate
D000017:ABO Blood-Group System