Osteonecrosis of the femoral head in a human immunodeficiency virus type 1-infected patient with lipodystrophy.
Osteonecrosis of the femoral head is rare in human immunodeficiency virus (HIV)-infected patients. We describe a 37-year-old HIV-infected man who developed lipodystrophy after highly active antiretroviral therapy (HAART), leading to left leg disability. Radiography revealed osteonecrosis of the left femoral head, which appeared to be related to the antiretroviral therapy for HIV infection and subsequent development of lipodystrophy and hyperlipidemia. While osteonecrosis among Taiwanese HIV-infected patients is uncommon, the potential for the development of this long-term complication should be carefully monitored as more patients survive for longer periods after HAART.
Tsai
Yu-Chieh
YC
Department of Internal Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan.
Liu
Chen-Hua
CH
Liao
Chun-Hsing
CH
Chen
Mao-Yuan
MY
Hung
Chien-Ching
CC
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005271:Femur Head Necrosis / Q000209:etiology*; D015497:HIV-1; D006801:Humans; D008060:Lipodystrophy / Q000150:complications*; D008297:Male