title: [Malignant multifocal ENT tumors].
abstract: Of 6787 patients with ENT cancer, multifocal tumors were detected in 319 cases (4.7%). 306(95.9%) patients had two tumors, 13(4.1%)--three tumors. Synchronous and metachroneous tumors were diagnosed in 39.2 and 60.8% patients, respectively. Primary tumors located more frequently in the larynx (n = 146) and pharynx (n = 50). The second tumors were more often found in the lungs (25.5%), pharynx (22.1%), oral cavity (13.2%). In 84.9% patients with multifocal tumors the first and the second lesions arose in the same organ system--respiratory and gastrointestinal tracts. Metachroneous tumors developed more often 2-5 years (49.1%) after cure of the primary tumor.
authors.forename: A V
authors.initials: AV
authors.lastname: Vakker
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000453:epidemiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology / Q000473:pathology*; D010255:Paranasal Sinus Neoplasms / Q000473:pathology*; D010610:Pharyngeal Neoplasms / Q000453:epidemiology / Q000473:pathology*
vernacular_title: Zlokachestvennye pervichno-mnozhestvennye opukholi LOR-organov.