Cognitive performance in rats differing in their inborn anxiety.
There is profound evidence that cognitive processes and anxiety are interrelated. To learn more about this interaction, the authors tested rats bred for either high (HABs) or low (LABs) anxiety-related behavior in a modified hole board task. This task allows parallel investigation of various cognitive processes and possibly related behavioral dimensions, both under baseline conditions and during cognitively stressful situations. The authors provide evidence that the degree of anxiety is differentially associated with enhanced performance for distinct informational processes in rats. As HABs and LABs did not differ in their anxiety-related behavior after habituation, that is, in a familiar environment during appetitive learning, the authors conclude that anxiety behavior in naive HABs may be due to differential cognitive processing.
Ohl
Frauke
F
Behavioral Phenotyping, Max Planck Institute of Psychiatry, Munich, Germany. ohl@mpipsykl.mpg.de
Roedel
Angelika
A
Storch
Corinna
C
Holsboer
Florian
F
Landgraf
Rainer
R
D000818:Animals; D001007:Anxiety / Q000235:genetics*; D003071:Cognition / Q000502:physiology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D011930:Reaction Time / Q000235:genetics; D013045:Species Specificity