Endothelial function in the post-prandial state.
In recent years the endothelium has emerged as an important protective barrier against the development of atherosclerosis. Endothelial dysfunction, often characterised by impaired endothelium-dependent vasodilation, is generally considered to be an early marker of cardiovascular disease. Recently, it has been noted that the post-prandial state is associated with impaired endothelium-dependent vasodilation. Since man lives in a post-prandial state most of the day, prolonged exposure to dietary factors which impair endothelial function or delayed post-prandial recovery of the endothelium could negatively affect the cardiovascular risk profile. This review will focus on post-prandial endothelial function characterised by endothelium-dependent changes in vasomotion.
de Koning
Eelco J P
EJ
Department of Vascular Medicine and Diabetes F02.126, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. e.dekoning@azu.nl
Rabelink
Ton J
TJ
D002318:Cardiovascular Diseases / Q000503:physiopathology*; D004727:Endothelium / Q000187:drug effects / Q000502:physiology*; D005947:Glucose / Q000008:administration & dosage*; D006801:Humans; D008055:Lipids / Q000008:administration & dosage*; D018384:Oxidative Stress; D019518:Postprandial Period; D014664:Vasodilation / Q000502:physiology*
D008055:Lipids; D005947:Glucose