title: The structure of the C-cadherin ectodomain resolved.
abstract: In a recent issue of Science, Boggon et al. report the structure of the full-length C-cadherin ectodomain (CCAD1-5). Previous cell adhesion and direct force measurements demonstrated that the CCAD1-5 ectodomain is a functionally active adhesion molecule, and thus the determination of its structure is a significant achievement.
authors.affiliation: Department of Chemical and Biomolecular Engineering and, Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, IL 61801, USA.
authors.forename: Deborah
authors.initials: D
authors.lastname: Leckband
mesh_terms: D015820:Cadherins / Q000737:chemistry* / Q000378:metabolism; D015815:Cell Adhesion Molecules / Q000737:chemistry* / Q000378:metabolism; D011485:Protein Binding / Q000502:physiology; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D029867:Xenopus Proteins
chemical_list: C074260:CDH3 protein, Xenopus; D015820:Cadherins; D015815:Cell Adhesion Molecules; D029867:Xenopus Proteins