title: A practical synthesis of L-ribose.
abstract: L-Ribose was synthesized by a simple four-step method with overall yield of 76.3% from a protected L-arabinose derivative, which is a compatible intermediate for the synthesis of L-deoxyribose. The key step of this strategy is the Swern oxidation and subsequent stereoselective reduction accompanied by inversion of the 2-hydroxy group of protected L-arabinose.
authors.affiliation: Osaka University of Pharmaceutical Sciences, Takatsuki, Japan. akagi@gly.oups.ac.jp
authors.forename: Masao
authors.initials: M
authors.lastname: Akagi
authors.forename: Daichi
authors.initials: D
authors.lastname: Omae
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Tamura
authors.forename: Tetsujiro
authors.initials: T
authors.lastname: Ueda
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kumashiro
authors.forename: Hidehito
authors.initials: H
authors.lastname: Urata
mesh_terms: D001089:Arabinose / Q000737:chemistry*; D003855:Deoxyribose / Q000138:chemical synthesis / Q000737:chemistry; D009705:Nucleosides / Q000138:chemical synthesis / Q000737:chemistry; D012266:Ribose / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D009705:Nucleosides; D003855:Deoxyribose; D012266:Ribose; D001089:Arabinose