title: The effect of adnexal surgery on the ovarian response to stimulation in in vitro fertilization.
abstract: OBJECTIVE
  The effect of adnexal surgery on ovarian function is a controversial issue of high clinical significance. The purpose of this study was to assess the effect of adnexal surgery on ovarian function.
  
  
  METHODS
  All patients who underwent adnexal surgery in our department during an 8-year period (all records were obtained from the hospital database between January 1991 and December 1998) were cross-matched with our in vitro fertilization (IVF) database. We compared the baseline hormonal levels and the patients' response to IVF stimulation (assessed by the total amount of gonadotropins, maximal estradiol (E2) levels, number of retrieved and fertilized oocytes).
  
  
  RESULTS
  Sixty-four consecutive patients who underwent adnexal surgery were compared with 68 matched controls. Neither of the analyzed parameters were affected by the tubal surgery.
  
  
  CONCLUSIONS
  We conclude from our study adnexal surgery is not detrimental to ovarian function.
authors.affiliation: In Vitro Fertilization Unit, Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Aviv University, 52621, Tel Hashomer, Israel. adrian@netvision.net.il
authors.forename: Adrian
authors.initials: A
authors.lastname: Shulman
authors.forename: Hadar
authors.initials: H
authors.lastname: Marom
authors.forename: GabI
authors.initials: G
authors.lastname: Oelsner
authors.forename: Ariel
authors.initials: A
authors.lastname: Horowitz
authors.forename: Isaac
authors.initials: I
authors.lastname: Ben-Nun
authors.forename: Shlomo
authors.initials: S
authors.lastname: Mashiach
authors.forename: Jehoshua
authors.initials: J
authors.lastname: Dor
mesh_terms: D000290:Adnexa Uteri / Q000601:surgery*; D000328:Adult; D016022:Case-Control Studies; D004624:Embryo Transfer / Q000706:statistics & numerical data; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy; D010535:Laparoscopy / Q000009:adverse effects; D007813:Laparotomy / Q000009:adverse effects; D009865:Oocytes / Q000502:physiology; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D012489:Salpingostomy / Q000009:adverse effects
chemical_list: D004958:Estradiol