Sexual and urological dysfunction in multiple sclerosis: better understanding and improved therapies.
The fundamental strategy in treating multiple sclerosis patients with unstable bladders involves a combination of suppressing urgency and ensuring effective urinary drainage. Anti-cholinergics remain the first-line treatment, but alternative therapies are undergoing clinical trials. With a range of new pro-erectile oral medications available, interest has grown in treatment of multiple sclerosis-related erectile failure. Female sexual dysfunction is also now gaining some attention, with new classification criteria and methods for assessing and treating these patients.
DasGupta
Ranan
R
Department of UroNeurology, National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK. ranandg@yahoo.co.uk
Fowler
Clare J
CJ
D003307:Copulation / Q000187:drug effects / Q000502:physiology; D007172:Erectile Dysfunction / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D005836:Genitalia, Female / Q000187:drug effects / Q000294:innervation / Q000503:physiopathology; D005837:Genitalia, Male / Q000187:drug effects / Q000294:innervation / Q000503:physiopathology; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology* / Q000628:therapy; D001743:Urinary Bladder / Q000187:drug effects / Q000294:innervation / Q000503:physiopathology; D014555:Urination Disorders / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy