title: Helicoid shiftamers.
abstract: We report calculations on the activation barriers for antarafacial [1,7]-hydrogen shifts in various helical polyenes containing saturated substructures. Based on these calculations, we predict that the barrier for analogous hydrogen shifts in the infinite system-a [1,7]-shiftamer-is only approximately 14 kcal/mol if the reactant is preorganized in an appropriate helical conformation.
authors.affiliation: Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853-1301, USA.
authors.forename: Dean J
authors.initials: DJ
authors.lastname: Tantillo
authors.forename: Roald
authors.initials: R
authors.lastname: Hoffmann