title: [Prognostic value of the Knosp scale in trans-sphenoidal surgery for pituitary adenomas].
abstract: Various surgical approaches are available for the treatment of somatotroph pituitary adenomas. The treatment of choice remains surgical excision via transsphenoidal route. The results of that operation depend on the volume of the tumour, its suprasellar and parasellar extension, especially to the cavernous sinus. Modern neuroimaging by magnetic resonance provides visualization of the size and extension of the tumour, but invasion of the cavernous sinus space remains still a surgical diagnosis. According to intraoperative observations and proliferation marker (Ki-67) Knosp has evolved out radiological classification describing parasellar extension of pituitary adenomas. We present a series of 142 somatotroph pituitary adenomas surgically treated by transsphenoidal route. The radiological features of the tumours are described using Knosp classification. The results of surgery are analyzed with special reference to preoperative magnetic resonance findings. We found Knosp scale useful for prognostic classification for transsphenoidal surgery cases.
authors.affiliation: Kliniki Neurochirurgii Centralnego Szpitala Klinicznego Wojskowej Akademii Medycznej, Warszawie.
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Zieliński
authors.forename: Jan K
authors.initials: JK
authors.lastname: Podgórski
mesh_terms: D000236:Adenoma / Q000097:blood / Q000145:classification* / Q000175:diagnosis / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010911:Pituitary Neoplasms / Q000097:blood / Q000145:classification* / Q000175:diagnosis / Q000601:surgery*; D011379:Prognosis
chemical_list: D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone
vernacular_title: Wartość prognostyczna skali Knosp'a w operacjach przezklinowych gruczolaków przysadki mózgowej.