Cobalt-catalyzed Heck-type reaction of alkyl halides with styrenes.
A cobalt complex, CoCl2[1,6-bis(diphenylphosphino)hexane], catalyzes an alkylation reaction of styrenes in the presence of Me3SiCH2MgCl in ether to yield beta-alkylstyrenes. A variety of alkyl halides including alkyl chlorides can be employed as an alkyl source. A radical mechanism is strongly suggested for this alkylation reaction.
Ikeda
Yousuke
Y
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
Nakamura
Tomoaki
T
Yorimitsu
Hideki
H
Oshima
Koichiro
K