title: [Epidemiology of dengue infection in Ribeirão Preto, SP, Brazil].
abstract: OBJECTIVE
  To assess dengue transmission in a correctional facility for juvenile delinquents in Ribeirão Preto, state of São Paulo, Brazil.
  
  
  METHODS
  A serological and virology investigation was carried out among inmates and employees of a correctional facility for juvenile delinquents in Ribeirão Preto, Brazil. The study population consisted of 105 inmates and 91 employees representing 89% of the exposed. The collected blood was stored and processed using MAC-ELISA and virus isolation. A questionnaire was applied to each subject at the time of blood collection.
  
  
  RESULTS
  Of the total of blood samples collected (n=196), 42 (21.4%) were positive for IgM antibodies and 43 (21.9%) for IgG antibodies; of which, 15 were both IgM and IgG positive and 28 (14.3%) were IgG positive only. Serotype 1 dengue virus was isolated in 5 samples. Out of 42 IgM positive samples, 14 (33.0%) subjects did not have any physical complaints. The incidence rate was 23.8% and 18.6% among inmates and employees, respectively. The first cases in the facility were reported in 1997 and the last ones in March 1997 though results are suggestive of an earlier onset of transmission.
  
  
  CONCLUSIONS
  The high incidence rate of dengue infection can be explained by the high population density of the facility, high Aedes aegypti infestation, high numbers of asymptomatic subjects, and a higher transmission of disease in a closed setting.
authors.affiliation: Secretaria Municipal de Saúde de Ribeirão Preto, Ribeirão Preto, SP, Brasil. eugenia.rodrigues@saude.gov.br
authors.forename: Eugênia Maria Silveira
authors.initials: EM
authors.lastname: Rodrigues
authors.forename: Amaury Lélis
authors.initials: AL
authors.lastname: Dal-Fabbro
authors.forename: Rogério
authors.initials: R
authors.lastname: Salomao
authors.forename: Ivani Bisordi
authors.initials: IB
authors.lastname: Ferreira
authors.forename: Iray Maria
authors.initials: IM
authors.lastname: Rocco
authors.forename: Benedito Antonio Lopes da
authors.initials: BA
authors.lastname: Fonseca
mesh_terms: D000293:Adolescent; D000328:Adult; D000330:Aedes; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D003716:Dengue Virus / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D015994:Incidence; D008297:Male; D016036:Seroepidemiologic Studies
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Epidemiologia da infecção pela dengue em Ribeirão Preto, SP, Brasil.