title: The role of Toll-like receptors in immunity against mycobacterial infection.
abstract: Recent work implicates Toll-like receptor (TLR) proteins as regulators of innate immune cell activation induced by Mycobacterium tuberculosis, which continues to ravage nearly one-third of the world's population. Novel insights into how TLR proteins may dictate the nature and extent of cellular immune responses against this pathogen will be discussed.
authors.affiliation: The Pulmonary Center, Boston University School of Medicine, 80 E. Concord Street, Boston, MA 02118-2394, USA.
authors.forename: Kurt A
authors.initials: KA
authors.lastname: Heldwein
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Fenton
mesh_terms: D000818:Animals; D017951:Antigen Presentation; D000938:Antigen-Presenting Cells / Q000276:immunology; D017209:Apoptosis; D029721:Drosophila Proteins; D006801:Humans; D007113:Immunity, Innate; D008562:Membrane Glycoproteins / Q000819:agonists / Q000378:metabolism*; D009169:Mycobacterium tuberculosis / Q000276:immunology* / Q000472:pathogenicity; D011956:Receptors, Cell Surface / Q000819:agonists / Q000378:metabolism*; D015398:Signal Transduction; D051193:Toll-Like Receptors; D014376:Tuberculosis / Q000276:immunology*
chemical_list: D029721:Drosophila Proteins; D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D051193:Toll-Like Receptors