Urinary arsenic speciation in subjects with or without restriction from seafood dietary intake.
In order to understand whether ingestion of seafood affects the urinary arsenic metabolites. About 42 women and 36 men were recruited from the students, parents and teachers in Taipei Medical University and National Taiwan University. The study subjects were interviewed about dietary habits, cigarette smoking habits, drug and vitamin intake, and consumption of seafood. Urine samples were collected from study subjects before and after refraining from eating seafood for 3 days, respectively. The urine samples were frozen at -20 degrees C separated by high-performance liquid chromatography (HPLC), and on line linked to hydride generator atomic absorption spectrometry (HGAAS) to quantify the levels of various species of inorganic arsenic and its metabolites. The levels of arsenite (AsIII), arsenate (AsV), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), total inorganic arsenic metabolites, inorganic arsenic percent, MMA percent and DMA percent were similar before and after refraining from eating seafood for 3 days. The frequencies of fish, shellfish and seaweed dietary intake were not significantly correlated with urinary arsenic species.
Hsueh
Yu Mei
YM
Department of Public Health, School of Medicine, Taipei Medical University, No. 250, Wu Hsin Street, 110, Taipei, Taiwan, ROC. ymhsueh@tmu.edu.tw
Hsu
Miao Kan
MK
Chiou
Hung Yi
HY
Yang
Mo Hsiung
MH
Huang
Chuan Chieh
CC
Chen
Chien Jen
CJ
D000328:Adult; D017677:Age Distribution; D000818:Animals; D001151:Arsenic / Q000008:administration & dosage / Q000378:metabolism / Q000652:urine*; D001152:Arsenicals / Q000652:urine; D002101:Cacodylic Acid / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D004032:Diet; D005260:Female; D005399:Fishes; D006801:Humans; D008297:Male; D008875:Middle Aged; D017747:Seafood; D017678:Sex Distribution; D012907:Smoking; D013624:Taiwan
D001152:Arsenicals; D002101:Cacodylic Acid; C020300:monomethylarsonic acid; D001151:Arsenic