Comèl-Netherton syndrome and peeling skin syndrome type B: overlapping syndromes or one entity?
BACKGROUND
A 42-year-old male patient suffering from the rare Comèl-Netherton syndrome is reported, and the symptoms are discussed together with the results of light and electron microscopic examinations.


METHODS
Our case presented peeling skin syndrome type B with spontaneous, lifelong skin shedding with underlying erythema; however, with more careful studies, the hidden features of Comèl-Netherton syndrome were identified.


CONCLUSIONS
This is an example of a condition where there is no clear border between Comèl-Netherton syndrome and peeling skin syndrome type B, lending credence to a close relationship between the two syndromes.
Sárdy
Miklós
M
Department of Dermato-Venerology, Semmelweis University, Budapest, Hungary. sardy@bor.sote.hu
Fáy
Andrea
A
Kárpáti
Sarolta
S
Horváth
Attila
A
D000328:Adult; D004817:Epidermis / Q000473:pathology* / Q000648:ultrastructure*; D006801:Humans; D016114:Ichthyosis, X-Linked / Q000150:complications* / Q000473:pathology*; D008297:Male; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology*; D013577:Syndrome