The use of urinary gonadotrophins should be discouraged.
In view of concerns regarding the potential presence and infectivity of prion proteins in human urinary gonadotrophin preparations, together with the availability of both recombinant FSH and recombinant LH, it is argued that the use of urinary gonadotrophins should be discouraged.
Matorras
Roberto
R
Human Reproduction Unit, Hospital de Cruces, País Vasco University, Baracaldo, Vizcaya, Spain. matorras@hcru.osakidetza.net
Rodríguez-Escudero
Francisco J
FJ
D006062:Gonadotropins / Q000009:adverse effects / Q000302:isolation & purification* / Q000627:therapeutic use*; D006801:Humans; D011328:Prions / Q000652:urine; D011994:Recombinant Proteins / Q000627:therapeutic use; D014556:Urine / Q000737:chemistry*
D006062:Gonadotropins; D011328:Prions; D011994:Recombinant Proteins