[Application of fetal bone in repairing the defected part of osteoma resection].
OBJECTIVE
To investigate the clinical results used fetal bone repairing the defect after osteoma resection.


METHODS
In 8 hours after abortion, the fetal bones of four limbs were cut and kept in the normal saline with gentamycin. Then the graft was storaged under 6 degrees C-8 degrees C and the longest storage time was 48 hours. Since 1990, seven cases of osteoma had been cured with fetal bone graft. Among them, there were 5 males and 2 females, aged from 6 to 38 years, the bone defect volume ranged from 5.5 cm x 3.6 cm x 2.5 cm to 9.0 cm x 4.3 cm x 3.2 cm. During operation, the osteoma was resected radically, then the defected cavity was impacted with prepared fetal bone.


RESULTS
After operation, the general condition was good, all the incision wound healed primarily. Sixteen weeks after operation, the defected cavity was repaired completely and the medullary cavity reopened. Follow-up for 8 months to 5 years, no recurrence or side-effect were observed.


CONCLUSIONS
Because of the more rapid expansion and replacement effect, the stronger osteoinduction, and the lower immune response, the fetal bone is practical material for repairing the bone defect in osteoma resection.
Deng
W X
WX
Department of Orthopedic Surgery, 474 Hospital of PLA, URUmqui, Xinjiang, P. R. China 830011.
Zhao
H R
HR
Zhang
Z S
ZS
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D002648:Child; D005260:Female; D005333:Fetus; D005350:Fibroma / Q000601:surgery*; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000601:surgery; D006801:Humans; D008297:Male; D010016:Osteoma / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods; D013977:Tibia