title: Cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. Estimation of their incidence in French populations.
abstract: Eight new cases of reciprocal translocation in the domestic pig are described. All the rearrangements were highlighted using GTG banding techniques. Chromosome painting experiments were also carried out to confirm the proposed hypotheses and to accurately locate the breakpoints. Three translocations, rcp(4;6)(q21;p14), rcp(2;6)(p17;q27) and rcp(5;17)(p12;q13) were found in boars siring small litters (8.3 and 7.4 piglets born alive per litter, on average, for translocations 2/6 and 5/17, respectively). The remaining five, rcp(5;8)(p12;q21), rcp(15;17)(q24;q21), rcp(7;8)(q24;p21), rcp(5;8)(p11;p23) and rcp(3;15)(q27;q13) were identified in young boars controlled before entering reproduction. A decrease in prolificacy of 22% was estimated for the 3/15 translocation after reproduction of the boar carrier. A parental origin by inheritance of the translocation was established for the (5;8)(p11;p23) translocation. The overall incidence of reciprocal translocations in the French pig populations over the 2000/2001 period was estimated (0.34%).
authors.affiliation: UMR INRA-ENVT de cytogénétique des populations animales, Ecole nationale vétérinaire de Toulouse, 23 Chemin des capelles, 31076 Toulouse Cedex 3, France. a.ducos@envt.fr
authors.forename: Alain
authors.initials: A
authors.lastname: Ducos
authors.forename: Alain
authors.initials: A
authors.lastname: Pinton
authors.forename: Martine
authors.initials: M
authors.lastname: Yerle
authors.forename: Anne
authors.initials: A
authors.lastname: Séguéla
authors.forename: Hélène-Marie
authors.initials: HM
authors.lastname: Berland
authors.forename: Corinne
authors.initials: C
authors.lastname: Brun-Baronnat
authors.forename: Nathalie
authors.initials: N
authors.lastname: Bonnet
authors.forename: Roland
authors.initials: R
authors.lastname: Darré
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D020223:Chromosome Painting; D003582:Cytogenetics; D005260:Female; D005602:France; D005828:Genetics, Population; D007621:Karyotyping; D008297:Male; D013552:Swine / Q000235:genetics*; D014178:Translocation, Genetic