title: Cell markers in the recognition of acute myeloblastic leukaemia subtypes.
abstract: The diagnosis of acute myeloblastic leukaemia (AML) is based on cell morphology, cytogenetic and molecular changes, cell markers and clinical data. Our aim was to establish whether morphology and cell markers are comparable in the evaluation of AML. Bone marrow smears were analysed, and flow cytometry and monoclonal antibodies were used to determine cell type and maturity. Morphology and cell markers correlated differently in different AML subtypes.
authors.affiliation: University Medical Centre Ljubljana, Dept. of Haematology, Ljubljana, Slovenia.
authors.forename: Dusan
authors.initials: D
authors.lastname: Andoljsek
authors.forename: Irena
authors.initials: I
authors.lastname: Preloznik Zupan
authors.forename: Darja
authors.initials: D
authors.lastname: Zontar
authors.forename: Peter
authors.initials: P
authors.lastname: Cernelc
authors.forename: Uros
authors.initials: U
authors.lastname: Mlakar
authors.forename: Mojca
authors.initials: M
authors.lastname: Modic
authors.forename: Joze
authors.initials: J
authors.lastname: Pretnar
authors.forename: Samo
authors.initials: S
authors.lastname: Zver
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001854:Bone Marrow Cells / Q000737:chemistry / Q000166:cytology; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000145:classification / Q000175:diagnosis; D007947:Leukemia, Megakaryoblastic, Acute / Q000145:classification / Q000175:diagnosis; D007948:Leukemia, Monocytic, Acute / Q000145:classification / Q000175:diagnosis; D015470:Leukemia, Myeloid, Acute / Q000145:classification* / Q000175:diagnosis; D015479:Leukemia, Myelomonocytic, Acute / Q000145:classification / Q000175:diagnosis; D015473:Leukemia, Promyelocytic, Acute / Q000145:classification / Q000175:diagnosis
chemical_list: D015415:Biomarkers