title: [Studies on dynamic changes of SOD and MDA in cultured cells from Schistosoma japonicum schistosomula].
abstract: OBJECTIVE
  To observe the dynamic changes of superoxide dismutase(SOD) and maldondialdehyde(MDA) in cultured cells from Schistosoma japonicum schistosomula and to explore the degeneration process of cultured cells.
  
  
  METHODS
  Pyrogallol method and thiobarbituric acid method were used to determinate the levels of SOD and MDA, respectively, in the cells cultured for 0-54 days.
  
  
  RESULTS
  SOD in the cells reached a peak level on d12 of the early stage of culture and then decreased. The MDA levels in the cultures cells ascended gradually, and had two peaks on d18 and d48, during the period of culture.
  
  
  CONCLUSIONS
  The cultured cells from S. japonicum schistosomula degenerated progressively.
authors.affiliation: Department of Medical Parasitology, Research Laboratory of Schistosomiasis, Hubei Medical University, Wuhan 430071.
authors.forename: M
authors.initials: M
authors.lastname: Jiang
authors.forename: X
authors.initials: X
authors.lastname: Chen
authors.forename: H
authors.initials: H
authors.lastname: Dong
authors.forename: M
authors.initials: M
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Ni
authors.forename: S
authors.initials: S
authors.lastname: Zhou
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D008315:Malondialdehyde / Q000378:metabolism*; D012549:Schistosoma japonicum / Q000166:cytology / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D008315:Malondialdehyde; D013482:Superoxide Dismutase