[Idiopathic endometrial decidual reaction in a woman in postmenopause: immunocytochemical evaluation of estrogen and progesterone receptors and its corticoid binding globulin].
Endometrial decidual reaction in postmenopausal women without an evident exogenous or endogenous progesterone stimulus, is uncommon. The morphological findings are decidual transformation of the endometrial stroma, necrosis, cellular pleomorphism and in some cases hyperplastic glands that exhibit focal atypia raising the possibility of malignancy. We report the case of a 55 years old woman with an idiopathic endometrial decidual reaction. In this woman, immunocytochemistry of endometrial tissue demonstrated the absence of cytoplasmatic and nuclear estrogen receptors. Staining of nuclear progesterone receptors and cytoplasmatic corticoid binding globulin, exceeded the immunoreactivity observed in any period of the menstrual cycle.
Vasconcellos
Adriana
A
Departamentos de Ciencias Básicas, de Obstetricia y Ginecología, de Ciencias Preclínicas y Centro de Biotecnología en Reproducción, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile. avascon@ufro.cl
Villagrán
Eduardo
E
Peña
Patricio
P
Miska
Werner
W
Sánchez
Raúl
R
D003656:Decidua / Q000737:chemistry* / Q000187:drug effects; D004717:Endometrium / Q000737:chemistry / Q000187:drug effects / Q000473:pathology; D015914:Estrogen Replacement Therapy / Q000009:adverse effects; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D017698:Postmenopause; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D011987:Receptors, Steroid / Q000032:analysis*; D017154:Stromal Cells / Q000473:pathology; D014156:Transcortin / Q000032:analysis*
D004967:Estrogens; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D011987:Receptors, Steroid; D014156:Transcortin