title: [Review on transformed cell and tumorigenicity].
abstract: OBJECTIVE
  To explore the relationship between characteristics of transformed cell and tumorigenicity.
  
  
  METHODS
  Documents about transformed cell and tumorigenicity were reviewed in detail.
  
  
  RESULTS
  Normal biological characteristics and cell function could be maintained in non-tumorigenic transformed cell, but it was changed markedly in malignant transformed cell.
  
  
  CONCLUSIONS
  Non-tumorigenic transformed cell can be served as a standard cell line to study the function and growth characteristics of normal cell.
authors.affiliation: Department of Orthopedic Surgery, First University Hospital, West China University of Medical Sciences, Chengdu, Sichuan, P. R. China 610041.
authors.forename: R Q
authors.initials: RQ
authors.lastname: Wei
authors.forename: Z M
authors.initials: ZM
authors.lastname: Yang
authors.forename: S M
authors.initials: SM
authors.lastname: Li
mesh_terms: D000818:Animals; D002461:Cell Line, Transformed; D002471:Cell Transformation, Neoplastic; D002472:Cell Transformation, Viral; D006801:Humans; D013539:Simian virus 40; D023822:Tissue Engineering / Q000379:methods