title: Effect of haptic angulation on posterior capsule opacification in modern foldable lenses with a square, truncated optic edge.
abstract: OBJECTIVE
  To analyze the effect of different haptic angulations on posterior capsule opacification (PCO) in a modern foldable intraocular lens (IOL) with a square-edged optic designed to reduce the incidence of PCO.
  
  
  METHODS
  Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA.
  
  
  METHODS
  Ten Dutch Belted, serum Pasteurella-free pigmented rabbits of the same age and sex had bilateral phacoemulsification with endocapsular IOL implantation. The eyes were implanted with Centerflex IOLs (Rayner) with haptic angulations of 0 degree (n = 8), 5 degrees (n = 4), 10 degrees (n = 4), or 15 degrees (n = 4).
  
  
  RESULTS
  There was no statistical difference in central PCO, peripheral PCO, and measured IOL decentration among the angulation groups.
  
  
  CONCLUSIONS
  With the Centerflex IOL, haptic angulation did not seem to be a significant factor influencing PCO. It appears that the barrier effect of the IOL's truncated, square-edged optic overrides the angulation factor in preventing PCO.
authors.affiliation: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA.
authors.forename: Josef M
authors.initials: JM
authors.lastname: Schmidbauer
authors.forename: Marcela
authors.initials: M
authors.lastname: Escobar-Gomez
authors.forename: David J
authors.initials: DJ
authors.lastname: Apple
authors.forename: Qun
authors.initials: Q
authors.lastname: Peng
authors.forename: Stella N
authors.initials: SN
authors.lastname: Arthur
authors.forename: Luis G
authors.initials: LG
authors.lastname: Vargas
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002386:Cataract / Q000473:pathology* / Q000517:prevention & control; D005260:Female; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D018918:Phacoemulsification; D011183:Postoperative Complications / Q000473:pathology* / Q000517:prevention & control; D011474:Prosthesis Design; D011817:Rabbits
chemical_list: D001672:Biocompatible Materials