Possible zoophilia associated with dopaminergic therapy in Parkinson disease.
OBJECTIVE
To report a patient with Parkinson disease (PD) who developed zoophilia as a possible complication of dopaminergic therapy.


METHODS
A 74-year-old man with advanced PD, who had wearing-off motor fluctuations, with a marked disability during the off periods and severe peak-of-dose choreiform dyskinesias, developed hypersexuality with zoophilia 5 days after standard levodopa was substituted for controlled-release levodopa and the dose of bromocriptine was increased. The abnormal sexual behavior disappeared 2 days after the doses of standard levodopa and of bromocriptine were reduced.


CONCLUSIONS
Hypersexuality is a known complication in PD patients undergoing dopaminergic therapy. However, the possible development of zoophilia due to these drugs, as was the case in our patient, is exceptional.


CONCLUSIONS
Zoophilia should be considered as a possible behavioral complication of dopaminergic therapy in PD patients.
Jiménez-Jiménez
Felix Javier
FJ
Department of Medicine-Neurology, Hospital Príncipe de Asturias, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain. fjimenezj@meditex.es
Sayed
Youssef
Y
García-Soldevilla
Miguel Angel
MA
Barcenilla
Beatriz
B
D000368:Aged; D000818:Animals; D001971:Bromocriptine / Q000009:adverse effects*; D004285:Dogs; D015259:Dopamine Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000009:adverse effects*; D008297:Male; D001523:Mental Disorders / Q000139:chemically induced*; D010300:Parkinson Disease / Q000188:drug therapy*; D012725:Sexual Behavior / Q000187:drug effects*
D015259:Dopamine Agents; D001971:Bromocriptine; D007980:Levodopa