title: Cognitive rehabilitation for spatial neglect following stroke.
abstract: BACKGROUND
  Unilateral spatial neglect is a failure to attend to one side of space. Various strategies have been used to treat these problems but evidence of their benefit has been lacking.
  
  
  OBJECTIVE
  To determine the effects of cognitive rehabilitation for spatial neglect following stroke as measured on impairment and disability level assessments, and destination on discharge from hospital. To determine whether any effects persist at follow-up assessment.
  
  
  METHODS
  We searched the Cochrane Stroke Group Trials Register (last searched February 2001), MEDLINE (1966-December 2000), EMBASE (1980-February 2001), CINAHL (1983-January 2001), PSYCLIT and CLINPSYCH (1974-February 2001). We handsearched relevant journals, screened reference lists from relevant articles and tracked citations using SCISEARCH.
  
  
  METHODS
  Controlled trials of cognitive rehabilitation for spatial neglect in stroke. Studies with mixed patient groups were excluded unless more than 75% of their sample were stroke patients or separate stroke data were available for stroke patients.
  
  
  METHODS
  Two reviewers independently selected trials, extracted data, and assessed trial quality.
  
  
  RESULTS
  We included 15 studies with 400 participants. A large number of different outcome measures were reported. Only six studies included a measure of disability and only four (111 participants) investigated persisting effects on any outcome. There was evidence that cognitive rehabilitation resulted in significant and persisting improvements in performance on impairment level assessments, although this varied depending on the test used. There was insufficient evidence to confirm or exclude an effect of cognitive rehabilitation at the level of disability or on destination following discharge from hospital.
  
  
  CONCLUSIONS
  There is some evidence that cognitive rehabilitation for spatial neglect improves performance on some impairment level tests but its effect on disability is unclear. Further well-designed RCTs are warranted as well as basic research to develop valid outcome measures.
authors.affiliation: Human Communication and Deafness, Faculty of Education, University of Manchester, Oxford Road, Manchester, UK, M13 9PL. audrey.bowen@man.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Bowen
authors.forename: N B
authors.initials: NB
authors.lastname: Lincoln
authors.forename: M
authors.initials: M
authors.lastname: Dewey
mesh_terms: D015928:Cognitive Behavioral Therapy; D006801:Humans; D010468:Perceptual Disorders / Q000209:etiology / Q000534:rehabilitation*; D016032:Randomized Controlled Trials as Topic; D012678:Sensation Disorders / Q000209:etiology / Q000534:rehabilitation; D013028:Space Perception; D020521:Stroke / Q000150:complications*; D000071939:Stroke Rehabilitation