title: [Electroencephalographic characteristics of West syndrome].
abstract: The study aimed at interictal electroencephalographic characteristics investigation in the patients with West syndrome. It has been carried out in 48 children, aged 3 months--2 years, the inpatients of Psychoneurology and Epilepsy Department, Russian Clinical Children Hospital No. 2, from March 1999 to march 2001. The following EEG awakeness types were detected: typical hypsarrithmia--8 (16.7%) patients; different variants of modified hypsarrithmia--35 (72.9%); a presence of focal epileptiform discharges, but not in the form of modified hypsarrithmia with focal component--3 (6.2%); an absence of epileptiform discharges--2 (4.2%). Typical and modified hypsarrithmia cases ratio was estimated as 18.6%:81.4%. Among the patients with modified hypsarrithmia, the following variants have been detected: synchronized variant of modified hypsarrithmia--35.3% of the cases with modified hypsarrithmia; asymmetric regional or unilateral hypsarrithmia--42.9%; hypsarrithmia with partial component--45.7%; hypsarrithmia with persisting "suppressive-burst" pattern--20% of the cases. Correct evaluation of clinical, electrophysiological and neurovisual data (clinico-electro-anatomical approach) facilitated the rational differential choice of antiepileptic therapy. The approach allows the early prognosis of disease course and its transformation to other epilepsy types.
authors.forename: A A
authors.initials: AA
authors.lastname: Kholin
authors.forename: K Iu
authors.initials: KIu
authors.lastname: Mukhin
authors.forename: A S
authors.initials: AS
authors.lastname: Petrukhin
authors.forename: E S
authors.initials: ES
authors.lastname: Il'ina
mesh_terms: D001921:Brain / Q000503:physiopathology*; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D012720:Severity of Illness Index; D013036:Spasms, Infantile / Q000175:diagnosis* / Q000503:physiopathology*