title: Familial ulcerative pyoderma gangrenosum: a report of 2 kindred.
abstract: Pyoderma gangrenosum is a rare, chronic ulcerative skin disease. It is a diagnosis of exclusion, after ruling out other causes of cutaneous ulceration. The etiology of pyoderma gangrenosum is poorly understood but is likely multifactorial. We describe 2 families affected by ulcerative pyoderma gangrenosum. This familial clustering suggests a possible genetic role in the development of pyoderma gangrenosum in some cases.
authors.affiliation: Vanderbilt University Medical Center, Department of Medicine, Nashville, Tennessee, USA.
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: Alberts
authors.forename: Hunter H
authors.initials: HH
authors.lastname: Sams
authors.forename: Jami L
authors.initials: JL
authors.lastname: Miller
authors.forename: Lloyd E
authors.initials: LE
authors.lastname: King
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D017511:Pyoderma Gangrenosum / Q000235:genetics* / Q000473:pathology*; D035781:Siblings