title: [The effect of argon-containing hypoxic gas environment on development of Japanese quail embryos].
abstract: In case of acute hypoxic hypoxia argon in the gas environment is favorable to survivability of laboratory animals (rats). Our purpose was to evaluate effects of an argon-containing hypoxic gas environment on embryogenesis of the Japanese quail (Cortunix cortunix japonica). Eggs of the Japanese quail were incubated in a pressurized chamber with a hypoxic gas environment differing in concentration of nitrogen and argon. In hypoxic (10% O2) oxygen-nitrogen and oxygen-nitrogen-argon atmospheres total mortality of embryos was observed no later than on day 7 of development. These gas mixtures also had a teratogenic effect. However, about 55% of argon in atmosphere prevented completely microcephalia and reduced in half incidence of other pathologies.
authors.forename: P E
authors.initials: PE
authors.lastname: Soldatov
authors.forename: O A
authors.initials: OA
authors.lastname: Dadasheva
authors.forename: T S
authors.initials: TS
authors.lastname: Gur'eva
authors.forename: L A
authors.initials: LA
authors.lastname: Lysenko
authors.forename: S E
authors.initials: SE
authors.lastname: Remizova
mesh_terms: D000818:Animals; D001128:Argon / Q000032:analysis* / Q000494:pharmacology; D003370:Coturnix / Q000196:embryology*; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D000860:Hypoxia / Q000503:physiopathology*; D008831:Microcephaly / Q000517:prevention & control; D009584:Nitrogen / Q000032:analysis* / Q000494:pharmacology
chemical_list: D001128:Argon; D009584:Nitrogen