The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.
The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum Chlorobia, whose members perform anoxygenic photosynthesis by the reductive tricarboxylic acid cycle. Genome comparisons have identified genes in C. tepidum that are highly conserved among photosynthetic species. Many of these have no assigned function and may play novel roles in photosynthesis or photobiology. Phylogenomic analysis reveals likely duplications of genes involved in biosynthetic pathways for photosynthesis and the metabolism of sulfur and nitrogen as well as strong similarities between metabolic processes in C. tepidum and many Archaeal species.
Eisen
Jonathan A
JA
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. jeisen@tigr.org
Nelson
Karen E
KE
Paulsen
Ian T
IT
Heidelberg
John F
JF
Wu
Martin
M
Dodson
Robert J
RJ
Deboy
Robert
R
Gwinn
Michelle L
ML
Nelson
William C
WC
Haft
Daniel H
DH
Hickey
Erin K
EK
Peterson
Jeremy D
JD
Durkin
A Scott
AS
Kolonay
James L
JL
Yang
Fan
F
Holt
Ingeborg
I
Umayam
Lowell A
LA
Mason
Tanya
T
Brenner
Michael
M
Shea
Terrance P
TP
Parksey
Debbie
D
Nierman
William C
WC
Feldblyum
Tamara V
TV
Hansen
Cheryl L
CL
Craven
M Brook
MB
Radune
Diana
D
Vamathevan
Jessica
J
Khouri
Hoda
H
White
Owen
O
Gruber
Tanja M
TM
Ketchum
Karen A
KA
Venter
J Craig
JC
Tettelin
Hervé
H
Bryant
Donald A
DA
Fraser
Claire M
CM
D002245:Carbon Dioxide / Q000378:metabolism; D019414:Chlorobi / Q000235:genetics* / Q000378:metabolism*; D002876:Chromosomes, Bacterial / Q000235:genetics; D002952:Citric Acid Cycle; D004260:DNA Repair; D004579:Electron Transport; D020440:Gene Duplication; D016680:Genome, Bacterial; D008954:Models, Biological; D008969:Molecular Sequence Data; D009584:Nitrogen / Q000378:metabolism; D018384:Oxidative Stress; D010788:Photosynthesis; D010802:Phylogeny; D014176:Protein Biosynthesis; D011758:Pyrroles / Q000378:metabolism; D013455:Sulfur / Q000378:metabolism; D013729:Terpenes / Q000378:metabolism; D045725:Tetrapyrroles; D014158:Transcription, Genetic
D011758:Pyrroles; D013729:Terpenes; D045725:Tetrapyrroles; D002245:Carbon Dioxide; D013455:Sulfur; D009584:Nitrogen