Primary acinic cell carcinoma of the breast.
Seven cases of this rare variant of breast carcinoma have been described in three previous publications. This paper describes an additional case, the first following chemotherapy, which in addition had an unfavourable prognosis. It also describes alterations in cell morphology, immunohistochemistry, and ultrastructure following chemotherapy.
Coyne
J D
JD
Department of Histopathology, Withington Hospital, Nell Lane, Manchester M20 2LR, UK. john.coyne@smuht.nwest.nhs.uk
Dervan
P A
PA
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D001943:Breast Neoplasms / Q000473:pathology*; D018267:Carcinoma, Acinar Cell / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology*; D011379:Prognosis