[Immunotropic properties of exoglycan obtained from the marine micro-organism Vibrio alginolyticus].
Immune system modulating activity of exoglycane isolated from culture media of Vibrio alginolyticus (strain 945-80) was investigated. The substance demonstrated stimulating activity on the humoral and cell immune system, potentiated phagocyte activity of macrophage and neutrophils, increased survival index of the animals infected by Gram-positive and Gram-negative bacteria.
Smolina
T P
TP
Research Institute of Epidemiology and Microbiology, Siberian Branch, Russian Academy of Medical Sciences, Vladivostok.
Gorshkova
R P
RP
Nazarenko
E L
EL
Ivanushko
L A
LA
Zaporozhets
T S
TS
Besednova
N N
NN
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001424:Bacterial Infections / Q000276:immunology* / Q000401:mortality; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007111:Immunity, Cellular / Q000187:drug effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010587:Phagocytosis / Q000187:drug effects; D011134:Polysaccharides / Q000302:isolation & purification*; D014733:Vibrio / Q000737:chemistry*
D000276:Adjuvants, Immunologic; D011134:Polysaccharides