Release of hemorphin-5 from human hemoglobin by pancreatic elastase.
Opioid peptide hemorphin-5 (YPWTQ) was released from human hemoglobin by the action of pancreatic elastase. V-hemorphin-5 (VYPWTQ) was also released under the same conditions. The amount of hemorphin-5 was about 1/10 that of V-hemorphin-5. This is the first report showing release of hemorphin-5 only by the action of one enzyme.
Jinsmaa
Yunden
Y
Graduate School of Agriculture, Kyoto University, Uji, Japan.
Yoshikawa
Masaaki
M
D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D006454:Hemoglobins / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D010196:Pancreatic Elastase / Q000378:metabolism*; D010446:Peptide Fragments / Q000737:chemistry / Q000378:metabolism*
D006454:Hemoglobins; D010446:Peptide Fragments; C049858:hemorphin 5; D010196:Pancreatic Elastase