title: [Norwalk virus: recent findings].
abstract: Acute gastroenteritis due to Norwalk virus(NV), a member of the family Caliciviridae, is a common illness worldwide. NV is a human pathogen causing food-borne and water-borne diseases that occur in various epidemiological settings. The disease is mild and self-limiting and the symptomatic phase lasts 24 to 72 hours. Genetic analyses of the polymerase and the capsid protein indicate that NV is grouped into two clusters, genogroup I and genogroup II. The development of recombinant virus-like particles made a great impact on the development of diagnostic assays such as antigen ELISA and antibody ELISA. Strong control measures are needed to prevent oyster-related outbreaks.
authors.affiliation: Department of Virology II, National Institute of Infectious Diseases.
authors.forename: Naokazu
authors.initials: N
authors.lastname: Takeda
mesh_terms: D017250:Caliciviridae Infections / Q000821:virology*; D004797:Enzyme-Linked Immunosorbent Assay; D005516:Food Microbiology; D005759:Gastroenteritis / Q000821:virology*; D005838:Genotype; D006801:Humans; D009663:Norwalk virus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction