title: Insecticide treated curtains and allelic polymorphism of Plasmodium falciparum genes in a rural area of Burkina Faso (west Africa).
abstract: To assess the possible impact of insecticide treated curtains (ITC) on the composition of a Plasmodium falciparum population in a rural area of Burkina Faso, blood samples were collected during the rainy season of 1997 from 226 children aged 3-6 years, from 4 villages equipped with ITC and 2 control villages without ITC. The analysis of fragment lengths of 3 highly polymorphic P. falciparum genes (msp-1, msp-2 and glurp) revealed a maximum number of 3 alleles per infected person for each gene. The mean number of clones per infected person was similar in villages with and without ITC.
authors.affiliation: Department of Infectious and Tropical Diseases, LSHTM, UK.
authors.forename: A
authors.initials: A
authors.lastname: Chiucchiuini
authors.forename: H
authors.initials: H
authors.lastname: Babiker
authors.forename: L
authors.initials: L
authors.lastname: Ranford-Cartwright
authors.forename: N
authors.initials: N
authors.lastname: Cuzin-Ouattara
authors.forename: I
authors.initials: I
authors.lastname: Nebié
authors.forename: S N
authors.initials: SN
authors.lastname: Cousens
authors.forename: D
authors.initials: D
authors.lastname: Walliker
authors.forename: F
authors.initials: F
authors.lastname: Esposito
mesh_terms: D000483:Alleles; D000818:Animals; D000953:Antigens, Protozoan / Q000235:genetics; D001512:Bedding and Linens / Q000469:parasitology*; D002050:Burkina Faso; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007306:Insecticides / Q000494:pharmacology*; D008297:Male; D020066:Merozoite Surface Protein 1 / Q000235:genetics; D010963:Plasmodium falciparum / Q000187:drug effects / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000187:drug effects*; D015800:Protozoan Proteins / Q000235:genetics; D012423:Rural Health; D012621:Seasons
chemical_list: D000953:Antigens, Protozoan; D007306:Insecticides; D020066:Merozoite Surface Protein 1; D015800:Protozoan Proteins; C065974:merozoite surface protein 2, Plasmodium; C072492:glutamate-rich protein, Plasmodium