[Immunomodulating effect of lysozyme in acute cold stress].
It was shown that lysozyme (1 or 5 mg/kg) injection in Wistar rats cooled immersially caused potent immune modulating, antioxidant and hepatoprotector effects. Lysozyme effect was due to heavy erythrocytes and by cytokines induced in spleen (with glass-adhesion at 32-37 degrees C).
Avakian
A R
AR
Kursk State Medical University.
Lazarev
A I
AI
Prokopenko
L G
LG
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000917:Antibody Formation; D000975:Antioxidants / Q000627:therapeutic use*; D003080:Cold Temperature / Q000009:adverse effects*; D016207:Cytokines / Q000378:metabolism; D004912:Erythrocytes / Q000276:immunology; D007101:Immersion; D015227:Lipid Peroxidation / Q000187:drug effects; D009113:Muramidase / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000187:drug effects / Q000276:immunology; D013312:Stress, Physiological / Q000201:enzymology / Q000209:etiology / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000975:Antioxidants; D016207:Cytokines; D009113:Muramidase