[Prevalence of hypothyroidism and hyperthyroidism in Nord-Trondelag].
BACKGROUND
The objective of this survey was to examine the prevalence of thyroid disease including autoimmunity in Norway.


METHODS
All 94,009 inhabitants aged 20 and above in Nord-Trøndelag county, Norway were invited to participate in a health survey.


RESULTS
The prevalence of formerly diagnosed hyperthyroidism was 2.5% in women and 0.6% in men, hypothyroidism 4.8% and 0.9% respectively, increasing with age. In individuals without a history of thyroid disease the median, 2.5 and 97.5 percentiles for TSH (mU/l) were 1.8 and 0.49-5.7 for women and 1.5 and 0.56-4.6 for men. When excluding individuals with positive thyroid peroxidase antibodies (TPOAb), the 97.5 percentiles were 3.6 mU/l for women and 3.4 mU/l for men. The prevalence of pathological TSH values in women and men were TSH > or = 10 mu/l 0.9% and 0.4%; TSH 4.1-9.9 mU/l 5.1% and 3.7%; TSH < or = 0.05 mU/l 0.5% and 0.2%. The prevalence of positive TPOAb was 13.9% in women and 2.8% in men, the lowest percentage was seen with TSH 0.2-2.0 mU/l and increased both with higher and lower TSH values and was higher in women except for those with TSH > or = 10 mU/l (85% TPOAb positive).


CONCLUSIONS
In spite of a high prevalence of recognised thyroid disease in the population a considerable number have undiagnosed thyroid dysfunction and positive TPOAb.
Bjøro
Trine
T
Hormonlaboratoriet Aker universitetssykehus 0514 Oslo. trine.bjoro@ioks.uio.no
Holmen
Jostein
J
Krüger
Øystein
Ø
Midthjell
Kristian
K
Hunstad
Kristin
K
Schreiner
Thomas
T
Sandnes
Liv
L
Brochmann
Henrik
H
D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D005260:Female; D006042:Goiter / Q000097:blood / Q000453:epidemiology; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000453:epidemiology*; D007037:Hypothyroidism / Q000097:blood / Q000453:epidemiology*; D007453:Iodide Peroxidase / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D015995:Prevalence; D011795:Surveys and Questionnaires; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood
D000906:Antibodies; D013972:Thyrotropin; D007453:Iodide Peroxidase