title: Identification of susceptibility genes for complex metabolic diseases.
abstract: There are few successful attempts to identify genes for common, non-Mendelian diseases such as diabetes, hyperlipidemia, hypertension, etc. Such common disorders are typically both metabolically and genetically complex and the genetic technologies to identify their underlying susceptibility genes are still in their infancy. Nonetheless, genetic strategies have emerged that, when the technologies are fully developed, should allow similar success rates as for Mendelian diseases.
authors.affiliation: Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016, USA. cbogardu@mail.nih.gov
authors.forename: Clifton
authors.initials: C
authors.lastname: Bogardus
authors.forename: Leslie
authors.initials: L
authors.lastname: Baier
authors.forename: Paska
authors.initials: P
authors.lastname: Permana
authors.forename: Michal
authors.initials: M
authors.lastname: Prochazka
authors.forename: Johanna
authors.initials: J
authors.lastname: Wolford
authors.forename: Robert
authors.initials: R
authors.lastname: Hanson
mesh_terms: D003920:Diabetes Mellitus / Q000235:genetics*; D008040:Genetic Linkage; D020022:Genetic Predisposition to Disease; D006949:Hyperlipidemias / Q000235:genetics*; D006973:Hypertension / Q000235:genetics*; D010641:Phenotype