title: Ecteinascidins 770 and 786 from the Thai tunicate Ecteinascidia thurstoni.
abstract: Ecteinascidins 770 (1b) and 786 (3b) were isolated from the pretreated Thai tunicate Ecteinascidia thurstoni with potassium cyanide in buffer solution (pH 7). These structures were fully elucidated by extensive 2D NMR analysis.
authors.affiliation: Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phyathai Road, Bangkok 10330, Thailand. Khanit.S@chula.ac.th
authors.forename: Khanit
authors.initials: K
authors.lastname: Suwanborirux
authors.forename: Kornvika
authors.initials: K
authors.lastname: Charupant
authors.forename: Surattana
authors.initials: S
authors.lastname: Amnuoypol
authors.forename: Sunibhond
authors.initials: S
authors.lastname: Pummangura
authors.forename: Akinori
authors.initials: A
authors.lastname: Kubo
authors.forename: Naoki
authors.initials: N
authors.lastname: Saito
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000995:Antitubercular Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002021:Buffers; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D020128:Inhibitory Concentration 50; D007546:Isoquinolines; D007624:KB Cells / Q000187:drug effects; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D019906:Nuclear Magnetic Resonance, Biomolecular; D011190:Potassium Cyanide; D013785:Thailand; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014561:Urochordata / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D000995:Antitubercular Agents; D002021:Buffers; D006576:Heterocyclic Compounds, 4 or More Rings; D007546:Isoquinolines; C464992:ecteinascidin 770; C464993:ecteinascidin 786; D011190:Potassium Cyanide