title: Views of transcription initiation.
abstract: Initiation of transcription is the first step in gene expression and a major point of regulation. Recent structural studies reveal the nature of the initiating complex and suggest new ways of accomplishing the processes required for initiation.
authors.affiliation: Department of Biochemistry and Biophysics, University of California, San Francisco, 94143, USA.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Young
authors.forename: Tanja M
authors.initials: TM
authors.lastname: Gruber
authors.forename: Carol A
authors.initials: CA
authors.lastname: Gross
mesh_terms: D000818:Animals; D012321:DNA-Directed RNA Polymerases / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial / Q000235:genetics; D006801:Humans; D015394:Molecular Structure; D011401:Promoter Regions, Genetic / Q000235:genetics; D017434:Protein Structure, Tertiary / Q000235:genetics; D012333:RNA, Messenger / Q000096:biosynthesis* / Q000235:genetics*; D024363:Transcription Initiation Site / Q000502:physiology*; D014158:Transcription, Genetic / Q000235:genetics*
chemical_list: D012333:RNA, Messenger; D012321:DNA-Directed RNA Polymerases