title: Mouthpiece versus facemask for delivery of nebulized salbutamol in exacerbated childhood asthma.
abstract: We compared the bronchodilator response to salbutamol (albuterol) delivered by a compressed air nebulizer through a mouthpiece and via a facemask in 18 asthmatic children, to determine the most appropriate delivery method. Patients using a mouthpiece had significantly better mean percent increases in forced expiratory volume in 1 sec (FEV1) and in forced vital capacity (FVC) than those using a facemask 30 min after inhalation (FEV1, 56.4 +/- 32.6% vs. 28.9 +/- 19.1%, FVC: 34.4 +/- 26.4% vs. 7.5 +/- 14.9%, respectively). Nebulized therapy plays an important role in the management of bronchial asthma in children and should be delivered by a mouthpiece whenever possible in cases of exacerbated asthma.
authors.affiliation: Second Department of Pediatrics, Toho University School of Medicine, Tokyo, Japan. masa1114@polaris.med.toho-u.ac.jp
authors.forename: Masaru
authors.initials: M
authors.lastname: Kishida
authors.forename: Istuo
authors.initials: I
authors.lastname: Suzuki
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Kabayama
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Koshibu
authors.forename: Masako
authors.initials: M
authors.lastname: Izawa
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Takeshita
authors.forename: Fumiko
authors.initials: F
authors.lastname: Kurita
authors.forename: Mari
authors.initials: M
authors.lastname: Okada
authors.forename: Noriaki
authors.initials: N
authors.lastname: Shinomiya
authors.forename: Tsugutoshi
authors.initials: T
authors.lastname: Aoki
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000420:Albuterol / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D002648:Child; D004867:Equipment Design; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008397:Masks; D009330:Nebulizers and Vaporizers; D016896:Treatment Outcome
chemical_list: D001993:Bronchodilator Agents; D000420:Albuterol