title: In-vivo proton magnetic resonance spectroscopy in adnexal lesions.
abstract: OBJECTIVE
  To explore the in-vivo 1H- MR spectral features of adnexal lesions and to characterize the spectral patterns of various pathologic entities.
  
  
  METHODS
  Thirty-one patients with surgically and histopathologically confirmed adnexal lesions underwent short echo-time STEAM (stimulated echo acquisition method) 1H- MR spectroscopy, and the results obtained were analysed.
  
  
  RESULTS
  The methylene present in fatty acid chains gave rise to a lipid peak of 1.3 ppm in the 1H- MR spectra of most malignant tumors and benign teratomas. This same peak was not observed, however, in the spectra of benign ovarian epithelial tumors: in a number of these, a peak of 5.2 ppm, due to the presence of the olefine group (-CH=CH-) was noted. The ratios of lipid peak at 1.3 ppm to water peak (lipid/water ratios) varied between disease groups, and in some benign teratomas was characteristically high.
  
  
  CONCLUSIONS
  An intense lipid peak at 1.3 ppm is observed in malignant ovarian tumors but not in benign epithelial tumors. 1H- MRS may therefore be helpful in the differential diagnosis of adnexal lesions.
authors.affiliation: Department of Radiology, Inha University College of Medicine, Incheon, South Korea.
authors.forename: Seong Whi
authors.initials: SW
authors.lastname: Cho
authors.forename: Soon Gu
authors.initials: SG
authors.lastname: Cho
authors.forename: Jung Hee
authors.initials: JH
authors.lastname: Lee
authors.forename: Hyung Jin
authors.initials: HJ
authors.lastname: Kim
authors.forename: Myung Kwan
authors.initials: MK
authors.lastname: Lim
authors.forename: Jong Hwa
authors.initials: JH
authors.lastname: Kim
authors.forename: Chang Hae
authors.initials: CH
authors.lastname: Suh
mesh_terms: D000291:Adnexal Diseases / Q000175:diagnosis*; D000328:Adult; D000368:Aged; D018291:Cystadenoma, Mucinous / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis; D011522:Protons; D013724:Teratoma / Q000175:diagnosis; D014594:Uterine Neoplasms / Q000175:diagnosis
chemical_list: D011522:Protons