title: Oxygenation of bisphenol A to quinones by polyphenol oxidase in vegetables.
abstract: To understand conversion of bisphenol A and its related compounds under some chemical and biological environments, oxidation of these compounds was performed. Bisphenol A was oxidized to monoquinone and bisquinone derivatives by Fremy's salt, a radical oxidant; but salcomine and alkali did not catalyze the oxidation by molecular oxygen. Bisphenol A, bisphenol B, and 3,4'-(1-methylethylidene)bisphenol were converted to their monoquinone derivatives in the presence of oxygen and polyphenol oxidase from mushroom at 25 degrees C at pH 6.5. Among crude enzyme solutions of fruits and vegetables, potato, mushroom, eggplant, edible burdock, and yacon showed remarkable oxidative activity on bisphenol A. The highest activity was observed in potato, and the main product obtained by the enzymatic oxygenation was the monoquinone derivative of bisphenol A, accompanied by a small amount of the bisquinone derivative. The oxidation reactions found here will be useful for developing techniques for elimination of phenolic endocrine disrupters from the environment.
authors.affiliation: National Food Research Institute, 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan. mitsuru@nfri.affrc.go.jp
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Yoshida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ono
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Mori
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Chuda
authors.forename: Motoyuki
authors.initials: M
authors.lastname: Mori
mesh_terms: D000363:Agaricales / Q000201:enzymology; D001559:Benzhydryl Compounds; D004156:Catechol Oxidase / Q000378:metabolism*; D005638:Fruit / Q000201:enzymology; D016877:Oxidants / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000494:pharmacology; D010636:Phenols / Q000378:metabolism*; D011809:Quinones / Q000378:metabolism; D014675:Vegetables / Q000201:enzymology*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004156:Catechol Oxidase; D016877:Oxidants; D010100:Oxygen; D010636:Phenols; D011809:Quinones; C006780:bisphenol A; D000098826:Bisphenol A Compounds