title: Multidrug and broad-spectrum cephalosporin resistance among Salmonella enterica serotype enteritidis clinical isolates in southern Italy.
abstract: From 1992 to 1997, only six sporadic isolates of Salmonella enterica serotype Enteritidis from patients with cases of gastroenteritis in southern Italy exhibited resistance to broad-spectrum cephalosporins. Five isolates produced SHV-12, and one isolate encoded a class C beta-lactamase. The bla(SHV-12) gene was located in at least two different self-transferable plasmids, one of which also carried a novel class 1 integron.
authors.affiliation: Laboratory of Bacteriology and Medical Mycology, Istituto Superiore di Sanità, Rome, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Villa
authors.forename: Caterina
authors.initials: C
authors.lastname: Mammina
authors.forename: Vivi
authors.initials: V
authors.lastname: Miriagou
authors.forename: Leonidas S
authors.initials: LS
authors.lastname: Tzouvelekis
authors.forename: Panayotis T
authors.initials: PT
authors.lastname: Tassios
authors.forename: Antonino
authors.initials: A
authors.lastname: Nastasi
authors.forename: Alessandra
authors.initials: A
authors.lastname: Carattoli
mesh_terms: D001483:Base Sequence; D018550:Cephalosporin Resistance; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D005759:Gastroenteritis / Q000188:drug therapy / Q000382:microbiology; D005798:Genes, Bacterial; D006801:Humans; D007558:Italy; D010957:Plasmids / Q000235:genetics; D012480:Salmonella Infections / Q000188:drug therapy / Q000382:microbiology; D012477:Salmonella enteritidis / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D001618:beta-Lactamases / Q000145:classification / Q000235:genetics
chemical_list: C107198:beta-lactamase SHV-12; D001618:beta-Lactamases