title: Persistent hyperlipasemia caused by macrolipase in an adolescent.
abstract: Serum amylase and lipase frequently rise during bouts of acute pancreatitis, and measurement of these enzymes provides important diagnostic information. We report a pediatric patient with persistent elevations of serum lipase resulting from macrolipasemia, a complex of lipase with IgG, rather than pancreatitis.
authors.affiliation: Department of Pediatrics, Washington University School of Medicine, St Louis Children's Hospital, Missouri 63110, USA.
authors.forename: James P
authors.initials: JP
authors.lastname: Keating
authors.forename: Mark E
authors.initials: ME
authors.lastname: Lowe
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007158:Immunologic Techniques; D008049:Lipase / Q000097:blood* / Q000276:immunology*; D046911:Macromolecular Substances; D008659:Metabolic Diseases / Q000175:diagnosis*; D010195:Pancreatitis / Q000175:diagnosis
chemical_list: D007074:Immunoglobulin G; D046911:Macromolecular Substances; D008049:Lipase