title: [Levels of lipid peroxidation products and activity of antiradical defense enzymes in blood of patients with Bechterew disease].
abstract: OBJECTIVE
  To study lipid peroxidation (LPO) in Bechterev's disease (BD) treated with antiinflammatory and antioxidant drugs.
  
  
  METHODS
  LPO was estimated in 75 BD patients before medication and during this treatment. 30 healthy volunteers served control.
  
  
  RESULTS
  Levels of LPO products was high but activity of antioxidant defense enzymes low in BD patients.
  
  
  CONCLUSIONS
  Antiinflammatory drugs meloxicam, indometacin and an antioxidant drug triovit depressed LPO activity, improve the patients' condition and results of functional tests.
authors.forename: O V
authors.initials: OV
authors.lastname: Mitrofanova
authors.forename: V V
authors.initials: VV
authors.lastname: Bagirova
authors.forename: S I
authors.initials: SI
authors.lastname: Krasikov
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage / Q000627:therapeutic use; D015227:Lipid Peroxidation; D008297:Male; D000077239:Meloxicam; D013167:Spondylitis, Ankylosing / Q000097:blood / Q000188:drug therapy / Q000201:enzymology* / Q000378:metabolism*; D013843:Thiazines / Q000008:administration & dosage / Q000627:therapeutic use; D013844:Thiazoles / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants; D005609:Free Radicals; D013843:Thiazines; D013844:Thiazoles; D000077239:Meloxicam; D007213:Indomethacin