Enantioselective hydrolysis of o-nitrostyrene oxide by whole cells of Aspergillus niger CGMCC 0496.
The asymmetric biohydrolysis is described of o-nitrostyrene oxide with high selectivity by whole cells of Aspergillus niger CGMCC 0496. Both the epoxide and diol could be obtained in a high state of optical purity (over 98%). Product inhibition was found when using a high ratio of substrate to cells.
Jin
Hao
H
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.
Li
Zu-yi
ZY
D001234:Aspergillus niger / Q000378:metabolism*; D004852:Epoxy Compounds / Q000378:metabolism*; D006868:Hydrolysis; D013237:Stereoisomerism
C469756:2-nitrostyrene oxide; D004852:Epoxy Compounds