title: Modification of the swern oxidation: use of a recyclable, polystyrene bound sulfoxide.
abstract: A method has been developed for the oxidation of sulfides to sulfoxides on polystyrene resin. The polystyrene bound sulfoxide may be used in Swern oxidation reactions, and the used reagent may be regenerated by oxidation with tert-butylhydrogen peroxide.
authors.affiliation: Chemical Sciences, Wyeth Research, 401N. Middletown Rd., Pearl River, NY 10965, USA. coledc@wyeth.com
authors.forename: Derek C
authors.initials: DC
authors.lastname: Cole
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Stock
authors.forename: Jo Anne
authors.initials: JA
authors.lastname: Kappel
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D001557:Benzenesulfonates / Q000737:chemistry; D002234:Carbodiimides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D011137:Polystyrenes / Q000737:chemistry*; D011422:Propionates / Q000737:chemistry; D013440:Sulfides / Q000737:chemistry; D013450:Sulfones / Q000737:chemistry; D013454:Sulfoxides / Q000737:chemistry*; D020122:tert-Butylhydroperoxide / Q000737:chemistry
chemical_list: D000438:Alcohols; D001557:Benzenesulfonates; D002234:Carbodiimides; D011137:Polystyrenes; D011422:Propionates; D013440:Sulfides; D013450:Sulfones; D013454:Sulfoxides; C017526:3-methylthiopropionate; C081611:1,3-diisopropylcarbodiimide; D020122:tert-Butylhydroperoxide; C029501:4-toluenesulfonic acid