Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei.
Pal
Arun
A
Wellcome Trust Laboratories for Molecular Parasitology, Department of Biological Sciences and Centre for Molecular Microbiology and Infection, Imperial College of Science, Technology and Medicine, Exhibition Road, SW7 2AY, London, UK.
Hall
Belinda S
BS
Field
Mark C
MC
D000818:Animals; D004705:Endocytosis; D008077:Lipoproteins, LDL / Q000378:metabolism*; D021261:Parasitic Sensitivity Tests / Q000379:methods; D011973:Receptors, LDL / Q000378:metabolism; D013498:Suramin / Q000378:metabolism* / Q000494:pharmacology; D014344:Trypanocidal Agents / Q000378:metabolism* / Q000494:pharmacology; D014346:Trypanosoma brucei brucei / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D014353:Trypanosomiasis, African / Q000469:parasitology; D020695:rab4 GTP-Binding Proteins / Q000235:genetics / Q000378:metabolism; D020696:rab5 GTP-Binding Proteins / Q000235:genetics / Q000378:metabolism
D008077:Lipoproteins, LDL; D011973:Receptors, LDL; D014344:Trypanocidal Agents; D013498:Suramin; D020695:rab4 GTP-Binding Proteins; D020696:rab5 GTP-Binding Proteins