Lymphoepithelioma-like carcinoma of oral cavity: report of three cases and literature review.
Lymphoepithelioma-like carcinoma is a rare tumour in the oral cavity and is characterized histologically by non-keratinizing, undifferentiated squamous cell carcinoma with lymphocytic infiltration. Three consecutive cases of intraoral lymphoepithelioma-like carcinoma are reported. A review of the literature reveals a similar biological behaviour to that of nasopharyngeal lymphoepithelioma: a high incidence of cervical nodal spread and remarkable radiosensitivity. Chemotherapy should be considered when nodal or distant metastases are present. The association of the Epstein-Barr virus with this tumour remains unclear but our experience suggests a positive correlation in Chinese individuals.
Chow
T L
TL
Department of Surgery, United Christian Hospital, Kowloon, Hong Kong.
Chow
T K
TK
Lui
Y H
YH
Sze
W M
WM
Yuen
N W F
NW
Kwok
S P Y
SP
D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000821:virology; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006723:Hong Kong; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology / Q000821:virology; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology* / Q000821:virology; D010157:Palatal Neoplasms / Q000473:pathology / Q000821:virology; D010160:Palate, Soft