Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.
Adequate control of HIV requires impairing the infection, replication and spread of the virus, no small task given the extraordinary capacity of HIV to exploit the cell's molecular machinery in the course of infection. Understanding the dynamic interplay of host cell and virus is essential to the effort to eradicate HIV.
Greene
Warner C
WC
Gladstone Institute of Virology and Immunology, Department of Medicine, University of California at San Francisco, San Francisco, California, USA. wgreene@gladstone.ucsf.edu
Peterlin
B Matija
BM
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000503:physiopathology*; D002477:Cells / Q000648:ultrastructure / Q000821:virology*; D006678:HIV / Q000472:pathogenicity / Q000502:physiology*; D015658:HIV Infections / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D022022:Nuclear Pore / Q000821:virology; D014779:Virus Replication