Familial ulcerative pyoderma gangrenosum: a report of 2 kindred.
Pyoderma gangrenosum is a rare, chronic ulcerative skin disease. It is a diagnosis of exclusion, after ruling out other causes of cutaneous ulceration. The etiology of pyoderma gangrenosum is poorly understood but is likely multifactorial. We describe 2 families affected by ulcerative pyoderma gangrenosum. This familial clustering suggests a possible genetic role in the development of pyoderma gangrenosum in some cases.
Alberts
Jennifer H
JH
Vanderbilt University Medical Center, Department of Medicine, Nashville, Tennessee, USA.
Sams
Hunter H
HH
Miller
Jami L
JL
King
Lloyd E
LE
D000328:Adult; D006801:Humans; D008297:Male; D017511:Pyoderma Gangrenosum / Q000235:genetics* / Q000473:pathology*; D035781:Siblings