title: Effect of an acrylic intraocular lens with a sharp posterior optic edge on posterior capsule opacification.
abstract: OBJECTIVE
  To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Sensar OptiEdge AR40e intraocular lens (IOL) (Allergan Surgical) with that of the round-edged design of the Sensar AR40 IOL. Setting Department of Ophthalmology, University of Vienna, Vienna, Austria.
  
  
  METHODS
  This prospective randomized patient- and examiner-masked study comprised 106 eyes of 53 patients with bilateral age-related cataract. Each patient had cataract surgery in both eyes and received an AR40 IOL in 1 eye and an AR40e IOL in the other eye. Postoperative examinations were at 1 week, 2 and 6 months, and 1 year. Digital slitlamp and digital retroillumination images of each eye were taken. The amount of PCO was assessed subjectively at the slitlamp and objectively using automated image-analysis software.
  
  
  RESULTS
  The AR40e group had significantly less regeneratory and fibrotic PCO 1 year after surgery. The mean automated image-analysis software PCO score (scale 0 to 10) was 2.19 in the AR40 group and 1.10 in the AR40e group (P <.001). The AR40e group had less peripheral fibrotic PCO. There was no significant difference in patient-reported edge glare between the 2 IOL groups.
  
  
  CONCLUSIONS
  The sharp-edged design of the Sensar OptiEdge AR40e IOL led to significantly less PCO than the round-edged AR40 IOL 1 year postoperatively.
authors.affiliation: Department of Ophthalmology, University of Vienna, Waehriger Guertel 18-20, 1090 Wien, Austria.
authors.forename: Wolf
authors.initials: W
authors.lastname: Buehl
authors.forename: Oliver
authors.initials: O
authors.lastname: Findl
authors.forename: Rupert
authors.initials: R
authors.lastname: Menapace
authors.forename: Georg
authors.initials: G
authors.lastname: Rainer
authors.forename: Stefan
authors.initials: S
authors.lastname: Sacu
authors.forename: Barbara
authors.initials: B
authors.lastname: Kiss
authors.forename: Vanessa
authors.initials: V
authors.lastname: Petternel
authors.forename: Michael
authors.initials: M
authors.lastname: Georgopoulos
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D019923:Capsulorhexis; D002386:Cataract / Q000517:prevention & control*; D004311:Double-Blind Method; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D018918:Phacoemulsification; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D011474:Prosthesis Design; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D000180:Acrylic Resins