title: New polyhydroxylated pyrrolidines derived from enantiopure 3,6-dihydro-2H-1,2-oxazines.
abstract: [reaction: see text] Diastereoselective hydroborations of enantiopure 3,6-dihydro-2H-1,2-oxazines led to dihydroxy-substituted 1,2-oxazines. Samarium diiodide-induced N-O bond cleavage generated 1,4-amino alcohols which were recyclized to polyhydroxylated pyrrolidines which are potential glycosidase inhibitors.
authors.affiliation: Institut für Chemie - Organische Chemie, Freie Universität Berlin, Takustrasse 3, D-14195 Berlin, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Pulz
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al-Harrasi
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Reissig