[Study on combined clinical manifestation and myocardial perfusion imaging with 99mTc-MIBI SPECT for diagnosing myocarditis].
In 568 cases suffering from upper-respiratory tract infection with sore throat and more than one of following clinical manifestations: arrhythmia, heart failure and chest pain or oppressive sensation over the chest(Group A), and another 108 cases without above clinical manifestations(Group B), myocardial perfusion imaging with 99mTc-MIBI SPECT was studied. The results revealed that the imaging in 404 cases (71.12%) of Group A supported diagnosis of myocarditis, but only 6 cases(5.56%) did so in Group B. Because of lacking the clinical manifestations of myocarditis but positive finding of CVB-IgM antibody was detected in their sera, we considered that the positive SPECT imaging in these six cases of Group B belonged to myocardial reaction due to virus infection. It was possible that some of them were suffering from subclinical type of myocarditis.
Qi
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Department of Cardiology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Zhou
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Shen
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D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D003384:Coxsackievirus Infections / Q000175:diagnosis; D029822:Enterovirus B, Human / Q000276:immunology / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000000981:diagnostic imaging* / Q000821:virology; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
D000914:Antibodies, Viral; D017256:Technetium Tc 99m Sestamibi