title: Cell movements during gastrulation: snail dependent and independent pathways.
abstract: The morphogenetic process of gastrulation requires multiple inputs and intricate coordination. Genetic analyses demonstrate critical roles of vertebrate and invertebrate Snail proteins in this process. Together with other regulatory molecules including Wnt and BMP, the Snail pathways specify cell fate and reorganize cellular machineries to coordinate morphological changes and cell movements during gastrulation.
authors.affiliation: Program in Molecular Medicine and Department of Cell Biology University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. Tony.Ip@umassmed.edu
authors.forename: Y Tony
authors.initials: YT
authors.lastname: Ip
authors.forename: Thomas
authors.initials: T
authors.lastname: Gridley
mesh_terms: D022005:Adherens Junctions; D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology; D002455:Cell Division / Q000502:physiology; D002465:Cell Movement / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000502:physiology*; D004330:Drosophila / Q000196:embryology; D029721:Drosophila Proteins / Q000502:physiology; D005775:Gastrula / Q000166:cytology*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D051379:Mice; D011518:Proto-Oncogene Proteins / Q000502:physiology; D011956:Receptors, Cell Surface / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology; D000071250:Snail Family Transcription Factors; D051193:Toll-Like Receptors; D014157:Transcription Factors / Q000502:physiology*; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D020741:rho GTP-Binding Proteins / Q000502:physiology
chemical_list: D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D011518:Proto-Oncogene Proteins; D011956:Receptors, Cell Surface; D000071250:Snail Family Transcription Factors; C068721:Tl protein, Drosophila; D051193:Toll-Like Receptors; D014157:Transcription Factors; D051153:Wnt Proteins; D029961:Zebrafish Proteins; C000604451:sna protein, Drosophila; D020741:rho GTP-Binding Proteins