title: An unusual case of osteoblastic metastasis from gastric carcinoma.
abstract: We report an unusual case of osteoblastic metastasis from gastric carcinoma. In this case, bone metastasis was the initial manifestation of the cancer. The laboratory findings revealed mild hypocalcemia and markedly elevated alkaline phosphatase levels. Plain X-ray showed mottled osteoblastic changes in the pelvis. Bone marrow and bone biopsy of the pelvis revealed metastatic adenocarcinoma with increased osteoblastic activity. An extensive search for the primary site revealed advanced gastric carcinoma, which was confirmed by endoscopic biopsy.
authors.affiliation: Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea. yschung@madang.ajou.ac.kr
authors.forename: Yoon-Sok
authors.initials: YS
authors.lastname: Chung
authors.forename: Tae-Young
authors.initials: TY
authors.lastname: Choi
authors.forename: Chang-Young
authors.initials: CY
authors.lastname: Ha
authors.forename: Hyeon-Man
authors.initials: HM
authors.lastname: Kim
authors.forename: Kwang-Jae
authors.initials: KJ
authors.lastname: Lee
authors.forename: Chan H
authors.initials: CH
authors.lastname: Park
authors.forename: Lorraine A
authors.initials: LA
authors.lastname: Fitzpatrick
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D010006:Osteoblasts / Q000000981:diagnostic imaging; D010388:Pelvis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013274:Stomach Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed