Correlation of Helicobacter pylori and gastric carcinoma.
BACKGROUND
Difference of opinion about the prevalence of H. pylori association with gastric cancer exists in the literature.


OBJECTIVE
To study the correlation of Helicobacter pylori (H. pylori) to gastric carcinoma.


METHODS
50 proved cases of gastric cancer were studied by rapid urease test, culture, histopathology and ELISA test for H. pylori IgG.


RESULTS
68% of cases of gastric cancer were found to be positive for H. pylori infection as compared to 74% of healthy controls.


CONCLUSIONS
The prevalence rate of H. pylori infection in our patients of gastric cancer was lower than in the control population though statistically not significant, suggesting that H. pylori may not be responsible for gastric carcinogenesis in this population.
Khanna
A K
AK
Department of Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi - 221005, India. akk_dr@satyam.net.in
Seth
P
P
Nath
G
G
Dixit
V K
VK
Kumar
M
M
D000328:Adult; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000453:epidemiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013274:Stomach Neoplasms / Q000382:microbiology* / Q000473:pathology