title: Estrogen induces elevation of cAMP-dependent protein kinase activity in immortalized hippocampal neurons: imaging in living cells.
abstract: 17beta-estradiol-stimulated PKA activation in living differentiated H19-7 cells was visualized using DR2, a cell-permeable fluorescent PKA substrate. Estradiol induced marked changes of fluorescence in cytosolic areas and these were inhibited by a PKA inhibitor.
authors.affiliation: Hyogo University School of Health Sciences, Japan. sheala@mcn.ne.jp
authors.forename: A S
authors.initials: AS
authors.lastname: Shingo
authors.forename: S
authors.initials: S
authors.lastname: Kito
mesh_terms: D000818:Animals; D002460:Cell Line; D017868:Cyclic AMP-Dependent Protein Kinases / Q000096:biosynthesis*; D004790:Enzyme Induction; D004958:Estradiol / Q000494:pharmacology*; D006624:Hippocampus / Q000201:enzymology*; D009474:Neurons / Q000201:enzymology*; D051381:Rats
chemical_list: D004958:Estradiol; D017868:Cyclic AMP-Dependent Protein Kinases