Lung surgery: identifying the subgroup at risk for sputum retention.
OBJECTIVE
Sputum retention after lung surgery is a potentially lethal condition, which can progress to atelectasis, pneumonia and respiratory failure requiring ventilatory support. Previous studies have concentrated on the treatment of postoperative respiratory complications but few have studied the risk factors for sputum retention. This prospective study was designed to identify the risk factors which may lead to the development of sputum retention after lung surgery.


METHODS
Three hundred sixty-one patients underwent lung surgery between January 1997 and December 1999 in a specialist Thoracic Surgery Unit (pneumonectomy, lobectomy, wedge or segmental resection, bullectomy, etc). Preoperative and intraoperative data collected prospectively included potential risk factors: chronic obstructive airway disease (COAD), forced expiratory volume in 1 s (FEV1)<50%, current smokers, ischaemic heart disease (IHD), cerebrovascular disease (CVA), resection of phrenic or recurrent laryngeal nerve, or absence of regional analgesia. Univariate and multivariate analysis was performed.


RESULTS
Sputum related complications occurred in 108 patients (30%). There were 17 deaths of which nine were due to complications related to sputum retention. Univariate analysis confirmed current smokers (n=128), COAD (n=103), IHD (n=41), prior history of CVA (n=16), FEV1<50% (n=48), and absence of regional anaesthesia as significant risk factors (P<0.01). The multivariate analysis confirmed current smokers, IHD and absence of regional anaesthesia as risk factors.


CONCLUSIONS
A subgroup of lung surgery patients at high risk for postoperative sputum retention can be predicted by the presence of one of the following criteria: current smokers, history of COAD, CVA, or IHD, and absence of regional analgesia. Prophylactic measures should be considered in this group to reduce the incidence of sputum retention.
Bonde
Pramod
P
Regional Thoracic Surgery Department, Royal Victoria Hospital, Grosevenor Road, Belfast BT12 6BA, UK.
McManus
Kieran
K
McAnespie
Martin
M
McGuigan
Jim
J
D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D011013:Pneumonectomy / Q000009:adverse effects*; D011184:Postoperative Period; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology; D012138:Respiratory Therapy; D018570:Risk Assessment; D012307:Risk Factors; D012907:Smoking; D013183:Sputum / Q000378:metabolism*; D014139:Tracheostomy / Q000379:methods