title: Aleukemic monocytic leukemia cutis.
abstract: Aleukemic leukemia cutis is a rare condition in which leukemic cells invade the skin before they appear in peripheral blood or bone marrow specimens. The condition frequently is misdiagnosed as atypical lymphoma. Generally, the diagnosis is made retrospectively, after the leukemic cells appear in peripheral blood or bone marrow samples. Immunohistochemical studies are the primary methods for diagnosis. Prognosis is usually poor. We describe the case of a 75-year-old woman with acute aleukemic monocytic leukemia cutis who developed systemic disease 1 1/2 years after skin involvement.
authors.affiliation: Department of Dermatology, Sheba Medical Center, Tel Hashomer, Israel. avivb@post.tau.ac.il
authors.forename: Aviv
authors.initials: A
authors.lastname: Barzilai
authors.forename: Ana
authors.initials: A
authors.lastname: Lyakhovitsky
authors.forename: Iris
authors.initials: I
authors.lastname: Goldberg
authors.forename: Dina
authors.initials: D
authors.lastname: Meytes
authors.forename: Henri
authors.initials: H
authors.lastname: Trau
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001856:Bone Marrow Examination; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007938:Leukemia / Q000473:pathology* / Q000628:therapy; D007951:Leukemia, Myeloid / Q000473:pathology* / Q000628:therapy; D017254:Leukemic Infiltration; D011241:Prednisone / Q000627:therapeutic use; D018714:Radiotherapy, Adjuvant; D012867:Skin / Q000473:pathology*; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone