title: Report of eight infants with acute infantile hemorrhagic edema and review of the literature.
abstract: Acute infantile hemorrhagic edema (AIHE) is a cutaneous leukocytoclastic vasculitis, clinically characterized by the symptom triad of fever, large purpuric skin lesions, and edema. The clinical picture has a violent onset, a short benign course, and spontaneous complete recovery. In this article, we present eight patients who were admitted with rashes on the skin and edema on the eyelids and extremities, and were diagnosed with AIHE according to their clinical and histopathological features (immunohistological study was also performed in three of them). Our purpose was to emphasize that, aside from Henoch-Schönlein purpura, meningococcemia, septicemia, and purpura fulminans, AIHE benign disorder should also be considered in the differential diagnosis to determine the clinical course and treatment protocol in patients with purpuric rashes.
authors.affiliation: Department of Pediatrics, Yüzüncü Yil University, Faculty of Medicine, Van, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Caksen
authors.forename: Dursun
authors.initials: D
authors.lastname: Odabaş
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kösem
authors.forename: Sükrü
authors.initials: S
authors.lastname: Arslan
authors.forename: Ahmet Faik
authors.initials: AF
authors.lastname: Oner
authors.forename: Bülent
authors.initials: B
authors.lastname: Ataş
authors.forename: Gürbüz
authors.initials: G
authors.lastname: Akçay
authors.forename: Nesrin
authors.initials: N
authors.lastname: Ceylan
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001707:Biopsy, Needle; D004487:Edema / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005500:Follow-Up Studies; D006470:Hemorrhage / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007223:Infant; D012075:Remission, Spontaneous; D012720:Severity of Illness Index; D016896:Treatment Outcome; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents