The outcome of autologous chondrocyte transplantation treatment of cartilage lesions in the knee.
Recent results of the clinical outcome of autologous chondrocyte transplantation (ACT) treatment in a group of 28 patients with focal femoral condyle cartilage lesions revealed a correlation trend with the quality of the in vitro cell culture matrix-protein synthesis. No impact of the patients' age and chondrocyte cryopreservation prior to implantation was observed. Further studies are needed to confirm the preliminary results.
Drobnic
Matej
M
Department of Orthopaedic Surgery, Clinical Centre, Zaloska 9, SI-1000 Ljubljana, Slovenia.
Kregar-Velikonja
Nevenka
N
Radosavljevic
Damjan
D
Gorensek
Miro
M
Koritnik
Branko
B
Malicev
Elvira
E
Wozniak
Gordana
G
Jeras
Matjaz
M
Knezevic
Miomir
M
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D053674:Aggrecans; D002358:Cartilage, Articular / Q000166:cytology; D017690:Cell Transplantation; D019902:Chondrocytes / Q000637:transplantation*; D024042:Collagen Type I / Q000032:analysis; D024043:Collagen Type II / Q000032:analysis; D016326:Extracellular Matrix Proteins; D006801:Humans; D007717:Knee; D037181:Lectins, C-Type; D008875:Middle Aged; D011509:Proteoglycans / Q000032:analysis; D014182:Transplantation, Autologous; D016896:Treatment Outcome
D053674:Aggrecans; D024042:Collagen Type I; D024043:Collagen Type II; D016326:Extracellular Matrix Proteins; D037181:Lectins, C-Type; D011509:Proteoglycans