An assessment of the comparative sensitization potential of some common isothiazolinones.
The isothiazolinones are known contact sensitizers. Data are presented which demonstrate that, in comparison with the chlorinated and dichlorinated compounds which share immunological cross-reactivity, the unchlorinated isothiazolinones have a lower potential for sensitization and no documented immunological cross-reaction with the chlorinated isothiazolinones.
Alexander
B R
BR
Thor Group Management Limited, Margate, Kent, United Kingdom. Bruce_Alexander@Microcare.uk.com
D000818:Animals; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D013844:Thiazoles / Q000009:adverse effects* / Q000737:chemistry
D011310:Preservatives, Pharmaceutical; D013844:Thiazoles