[Relationship between hypotension during hemodialysis and autonomic dysfunction in diabetic hemodialysis patients].
OBJECTIVE
To observe the change of autonomic nerve function in diabetes mellitus(DM) patients who receive hemodialysis and to explore the relationship between this change and hypotension during hemodialysis.


METHODS
Twenty-five DM patients and 40 chronic glomerulonephritis(CGN) patients who received hemodialysis were checked. We tested their coefficient of variation R-R(CVR-R) in ECG, difference of systolic blood pressure between lying and standing positions, and serum parathyroid hormone(PTH); monitored the decrease of blood pressure during hemodialysis.


RESULTS
The rate(80.0%) of autonomic dysfunction(AD) in DM group is significantly higher than that(57.5%, P < 0.05) in CGN group. The rate(37.2%) of hypotension in those who had AD was significantly higher than that(18.2%, P < 0.05) in those who had normal autonomic nerve function during hemodialysis. No significant difference was found in PTH between each group.


CONCLUSIONS
DM patients who receive hemodialysis are often complicated with AD, which is one of the reasons that causes hypotension during hemodialysis.
Ning
J
J
Department of Nephrology, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Sun
M
M
Ikeda
T
T
D000328:Adult; D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000209:etiology*; D003928:Diabetic Nephropathies / Q000150:complications / Q000628:therapy*; D005260:Female; D006801:Humans; D007022:Hypotension / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D014511:Uremia / Q000628:therapy