[Development of biodegradable polymer scaffolds for bone tissue engineering].
OBJECTIVE
To investigate the selection and manufacture of ideal extracellular matrix materials in bone tissue engineering.


METHODS
The recent literatures about biodegradable polymers served as culture scaffolds of osteoblasts were widely reviewed, the advantages and disadvantages of biodegradable synthetic polymers and natural polymers were analysed.


RESULTS
The ideal extracellular matrix material in bone tissue engineering should be made up of inorganic materials, synthetic polymers and natural polymers, which possesses morphological structure of three-dimensional foam with self-mediated drug slow delivery system of bone growth factors.


CONCLUSIONS
The design and manufacture of combined extracellular matrix materials in bone tissue engineering is a very important and urgent challenge.
Zheng
L
L
Department of Traumatology and Orthopedics, Nanfang Hospital, First Military Medical University, Guangzhou, Guangdong, P. R. China 510515.
Wang
Q
Q
Pei
G X
GX
D020341:Absorbable Implants; D000818:Animals; D018786:Bone Substitutes; D006801:Humans; D011108:Polymers; D019736:Prostheses and Implants; D023822:Tissue Engineering
D018786:Bone Substitutes; D011108:Polymers