title: Effect of chest wall vibration on dyspnea during exercise in chronic obstructive pulmonary disease.
abstract: To elucidate the effect of in-phase chest wall vibration (IPV) during exercise, 17 COPD male patients performed two constant-load exercise tests on a cycle ergometer with and without IPV. The Borg dyspnea score significantly decreased from IPV (-) to IPV (+) (from 13.6+/-2.9 to 12.5+/-2.9, P<0.01). IPV elicited a significant increase in V(O(2)) (P<0.005) and significant decreases in both VE/V(O(2)) (P<0.05) and respiratory frequency (P<0.05), but it did not elicit any changes in VE. The change in Borg score between IPV (+) and IPV (-) showed a significant positive correlation with % predicted V(O(2),max) (r=0.71) and FEV(1)/FVC (r=0.69). Patients in the responsive group (n=11) showed significantly lower FEV(1) (P<0.05) and higher DeltaN(2)/L (P<0.01) than patients in the non-responsive group (n=6). We conclude that IPV reduces dyspnea and improves respiratory efficiency during aerobic exercise in severe COPD.
authors.affiliation: The Pulmonary Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan.
authors.forename: Toshihide
authors.initials: T
authors.lastname: Fujie
authors.forename: Naoko
authors.initials: N
authors.lastname: Tojo
authors.forename: Naohiko
authors.initials: N
authors.lastname: Inase
authors.forename: Nobuo
authors.initials: N
authors.lastname: Nara
authors.forename: Ikuo
authors.initials: I
authors.lastname: Homma
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yoshizawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004417:Dyspnea / Q000503:physiopathology / Q000628:therapy*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009470:Muscle Spindles / Q000502:physiology; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology / Q000628:therapy*; D012125:Respiratory Center / Q000502:physiology; D012129:Respiratory Function Tests; D015656:Respiratory Mechanics; D012132:Respiratory Muscles / Q000294:innervation / Q000502:physiology; D014732:Vibration / Q000627:therapeutic use*