title: Predictors of complications in acute type B aortic dissection.
abstract: OBJECTIVE
  Medical treatment is generally advocated for patients with acute type B aortic dissection without complications. The objective of this retrospective analysis was to determine whether there are any initial findings that can help predict the long-term course of the disease.
  
  
  METHODS
  Case records of the 130 patients treated for type B aortic dissection between 1988 and 1997 were reviewed; 41 (31%) were operated on in the acute phase (<14 days), 31 (24%) were operated on in the chronic phase and 58 (45%) were treated medically.
  
  
  RESULTS
  Overall acute mortality was 10.8%; 22% for patients operated on in the early phase and 5.6% for medically treated patients. Age (P=0.002), persistent pain (P=0.01) and malperfusion (P=0.001) were significant independent predictors of the need for surgery. Paraplegia/para paresis (P=0.0001), leg ischaemia (P=0.003), pleural effusion (P=0.003), rupture (P=0.0001), shock (P=0.0001), age (P=0.003), cardiac failure (P=0.002) and aortic diameter >4.5 cm (P=0.002) were significant predictors of poor survival. Age and shock also emerged as independent risk factors. Patients without malperfusion (P=0.0001), pleural effusion (P=0.003), rupture (P=0.0001) and shock (P=0.0001) had a significantly better event-free survival (freedom from repeat surgery and death). The actuarial survival rate for high-risk patients (malperfusion, rupture, shock) was 62% at 1 year and 40% at 5 years; the corresponding values for low-risk patients were 94 and 84%, respectively.
  
  
  CONCLUSIONS
  Rupture, shock and malperfusion are significant predictors of poor survival in patients with acute type B aortic dissection.
authors.affiliation: Clinic of Cardiac Surgery, University Hospital Zurich, Zurich, Switzerland. michele.genoni@triemli.stzh.ch
authors.forename: M
authors.initials: M
authors.lastname: Genoni
authors.forename: M
authors.initials: M
authors.lastname: Paul
authors.forename: R
authors.initials: R
authors.lastname: Tavakoli
authors.forename: A
authors.initials: A
authors.lastname: Künzli
authors.forename: M
authors.initials: M
authors.lastname: Lachat
authors.forename: K
authors.initials: K
authors.lastname: Graves
authors.forename: B
authors.initials: B
authors.lastname: Seifert
authors.forename: M
authors.initials: M
authors.lastname: Turina
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000401:mortality* / Q000601:surgery; D001014:Aortic Aneurysm / Q000401:mortality* / Q000601:surgery; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis