title: Retrobulbar circulation in myopic patients with or without myopic choroidal neovascularisation.
abstract: OBJECTIVE
  To investigate the effect of myopia and myopic choroidal neovascularisation (CNV) on retrobulbar circulation in central retinal artery (CRA) and vein (CRV) and posterior ciliary artery (PCA).
  
  
  METHODS
  52 subjects with and without myopia were included in the study. Retrobulbar circulation was measured using colour Doppler imaging. Analysis of correlation of degree of myopia with blood flow velocity parameters was done. Circulatory differences between eyes of patients with unilateral neovascular degenerative myopia were estimated.
  
  
  RESULTS
  The analysis of correlation between dioptry and blood flow velocity in the CRA, CRV, and PCA showed a significant positive correlation. Axial length was also significantly correlated with CRA and CRV blood velocity and had a tendency to be correlated with PCA blood velocity. When compared with the fellow eye, the eye with myopic CNV had significantly higher resistivity index (RI) (p=0.048) in the PCA and no significant difference in the circulatory parameters of the CRA and CRV.
  
  
  CONCLUSIONS
  Central retinal and posterior ciliary blood velocity decreases with the increase of the degree of myopia. PCA RI is higher in myopic CNV.
authors.affiliation: Department of Ophthalmology, University of Tokyo, School of Medicine, Tokyo, Japan. galina-tky@umin.ac.jp
authors.forename: G
authors.initials: G
authors.lastname: Dimitrova
authors.forename: Y
authors.initials: Y
authors.lastname: Tamaki
authors.forename: S
authors.initials: S
authors.lastname: Kato
authors.forename: M
authors.initials: M
authors.lastname: Nagahara
mesh_terms: D000328:Adult; D000368:Aged; D020256:Choroidal Neovascularization / Q000150:complications / Q000503:physiopathology*; D019842:Ciliary Arteries / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000503:physiopathology*; D012039:Regional Blood Flow; D012161:Retinal Artery / Q000000981:diagnostic imaging*; D012169:Retinal Vein / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color