title: Angioplasty for coarctation in different aged patients.
abstract: BACKGROUND
  Differences in the indication and outcome of balloon angioplasty for coarctation in children and adults have not been elucidated sufficiently. The results of balloon angioplasty for coarctation are compared between pediatric and adult age groups.
  
  
  METHODS
  Balloon angioplasty for coarctation of the aorta was performed in 85 patients who were classified according to age and native coarctation/recoarctation. Groups A (patients aged <16 years, n = 32) and B (patients aged > or =16 years, n = 17) included patients with native coarctations. Groups rCoA A (patients aged <16 years, n = 33) and rCoA B (patients aged > or =16 years, n = 3) included patients with recoarctations. Follow-up included 2-dimensional Doppler scanning echocardiography and additional angiography or magnetic resonance imaging. Gradient reductions in groups were compared by use of the independent-samples t test. Kaplan-Meier and log-rank analyses were performed as a means of comparing long-term outcome.
  
  
  RESULTS
  No mortality occurred. Immediate success was equal in groups A, B, and rCoA A (94%). Dilatation was unsuccessful in 2 patients in group rCoA B. Pressure gradients decreased 23 mm Hg in group A, 31 mm Hg in group B, 18 mm Hg in group rCoA A, and 11 mm Hg in group rCoA B. Pressure gradient drops, compared between groups A and B, showed a significant difference (P <.001). The length of hospital stay ranged from 12 to 48 hours. The period of follow-up ranged from 6 months to 12 years (mean, 4.9 years). Kaplan-Meier curves of groups A and B are not different, as determined by means of log-rank analysis. No aneurysm formation was encountered.
  
  
  CONCLUSIONS
  The results of balloon angioplasty for native coarctation in both selected children and adults are excellent. In recoarctation, we recommend balloon angioplasty in the pediatric patients.
authors.affiliation: Heart Lung Center, University Medical Center Utrecht, The Netherlands.
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Walhout
authors.forename: Jaco C
authors.initials: JC
authors.lastname: Lekkerkerker
authors.forename: Sjef M P G
authors.initials: SM
authors.lastname: Ernst
authors.forename: Paul A
authors.initials: PA
authors.lastname: Hutter
authors.forename: Thijs H W M
authors.initials: TH
authors.lastname: Plokker
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Meijboom
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000800:Angioplasty, Balloon; D001017:Aortic Coarctation / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome