Echogenic bowel in intrauterine growth restriction fetuses: does this jeopardize the gut?
OBJECTIVE
To investigate the association between intrauterine growth restriction (IUGR) fetuses with echogenic bowel and high resistance in the umbilical artery and increased risk of developing neonatal necrotizing enterocolitis.


METHODS
We analyzed two groups: group 1, singleton IUGR fetuses with echogenic bowel or reversed diastolic flow in the umbilical artery, and group 2, neonates who were diagnosed as having neonatal necrotizing enterocolitis. In group 1, the pulsatility index of the superior mesenteric artery and celiac trunk were determined. In group 2, a retrospective analysis was carried out from the medical records of the neonates.


RESULTS
Fifteen fetuses with echogenic bowel and severe IUGR were evaluated by Doppler studies, and 21 neonates with neonatal necrotizing enterocolitis were reviewed. In group 1, none of the IUGR fetuses developed neonatal necrotizing enterocolitis, whereas in group 2, only one neonate was defined as IUGR. The mean gestational age at delivery did not differ statistically between the two groups (28.8 +/- 2.3 weeks versus 30.1 +/- 3.3 weeks), whereas the mean birth weight was significantly lower in the first group (700 +/- 200 g versus 1431 +/- 466 g in the second group, P <.001). The mean pulsatility index +/- standard deviation in the superior mesenteric artery and celiac trunk of the IUGR fetuses were 1.5 +/- 0.14 and 1.2 +/- 0.17, respectively, both being found significantly lower than those of normal, appropriate controls (1.9 +/- 0.15 and 1.7 +/- 0.1, respectively, P <.005).


CONCLUSIONS
Fetal echogenic bowel in IUGR fetuses is not associated with development of neonatal necrotizing enterocolitis. In these fetuses, vasodilatation in the superior mesenteric artery and celiac trunk have been demonstrated.
Achiron
Reuwen
R
Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel. rachiron@post.tau.ac.il
Mazkereth
Rami
R
Orvieto
Raoul
R
Kuint
Jacob
J
Lipitz
Shlomo
S
Rotstein
Zeev
Z
D020345:Enterocolitis, Necrotizing / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D005317:Fetal Growth Retardation / Q000150:complications / Q000000981:diagnostic imaging*; D005865:Gestational Age; D006801:Humans; D007422:Intestines / Q000000981:diagnostic imaging* / Q000196:embryology*; D011247:Pregnancy; D011336:Probability; D012189:Retrospective Studies; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal / Q000379:methods*; D014469:Umbilical Arteries / Q000000981:diagnostic imaging*; D014655:Vascular Resistance