Retinal visualization in an eye with corneal crystals using indocyanine green videoangiography.
OBJECTIVE
To report a patient in whom clear imaging of the retina, impossible with conventional methods, was obtained using indocyanine green (ICG) videoangiography.


METHODS
Interventional case report.


METHODS
A 31-year-old patient with nephropathic cystinosis and complaints of decreased vision in the left eye underwent a complete ophthalmologic evaluation, including conventional photography, fluorescein angiography, and ICG videoangiography.


RESULTS
With conventional methods (direct and indirect ophthalmoscopy, photography, and fluorescein angiography), the view of the left retina was obscured by densely packed corneal cystine crystals. During ICG angiography, clear imaging of the retina was obtained with near-infrared illumination.


CONCLUSIONS
Indocyanine green videoangiography can be a useful tool in cases with cystinosis and other corneal opacities, where visualization and imaging of the retina are important but impossible with conventional methods.
Tsilou
Ekaterini
E
Ophthalmic Genetics and Visual Function Branch, National Institutes of Health, Bethesda, MD 20892, USA. tsiloue@nei.nih.gov
Csaky
Karl
K
Rubin
Benjamin I
BI
Gahl
William
W
Kaiser-Kupfer
Muriel
M
D000328:Adult; D002829:Choroid / Q000098:blood supply; D020256:Choroidal Neovascularization / Q000175:diagnosis*; D004396:Coloring Agents; D003316:Corneal Diseases / Q000150:complications*; D003554:Cystinosis / Q000150:complications*; D005451:Fluorescein Angiography / Q000379:methods*; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D009887:Ophthalmoscopy; D010781:Photography; D012164:Retinal Diseases / Q000175:diagnosis*; D012171:Retinal Vessels / Q000473:pathology; D014792:Visual Acuity
D004396:Coloring Agents; D007208:Indocyanine Green