title: Phosphine-catalyzed annulation of thioamides and 2-alkynoates: a new synthesis of thiazolines.
abstract: The annulation of thioamides with 2-alkynoates and 2,3-dienoates under the catalysis of tri-n-butylphosphine was described. The annulation reaction provided a new entry to thiazolines, particularly those with 2-aryl substituents.
authors.affiliation: Chemical Development, GlaxoSmithKline, Five Moore Drive, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398, USA. bl10520@gsk.com
authors.forename: Bing
authors.initials: B
authors.lastname: Liu
authors.forename: Roman
authors.initials: R
authors.lastname: Davis
authors.forename: Biren
authors.initials: B
authors.lastname: Joshi
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Reynolds