title: Upper airway collapsibility: measurement techniques and therapeutic implications.
abstract: Several techniques are currently available that aim to characterize upper airway function/mechanics during wakefulness or sleep. Based on the concept of a Starling resistor, we propose a standardized protocol to measure the critical pressure (Pcrit) (an indicator of upper airway collapsibility) during sleep. The effect of therapeutic interventions such as weight loss, positional changes or uvulopalatopharyngoplasty on Pcrit is illustrated by data from the literature. We propose that measurement of Pcrit become implemented in the diagnostic work-up of selected patients with sleep-related breathing disorder to help making a correct therapeutic decision.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Antwerp, Belgium. An.Boudewijns@uza.be
authors.forename: A
authors.initials: A
authors.lastname: Boudewyns
authors.forename: A R
authors.initials: AR
authors.lastname: Schwartz
authors.forename: P H
authors.initials: PH
authors.lastname: Van de Heyning
mesh_terms: D000403:Airway Resistance; D006801:Humans; D010159:Palate / Q000601:surgery; D010614:Pharynx / Q000601:surgery; D012891:Sleep Apnea Syndromes / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D014609:Uvula / Q000601:surgery; D015431:Weight Loss