title: Nutritional status of beta-carotene, alpha-tocopherol and retinol in obese children.
abstract: We investigated the concentrations of beta-carotene, alpha-tocopherol, and retinol in obese children, together with assessment of the influence of relative body weight and plasma lipids. A lower plasma beta-carotene level was observed in the obese children, and plasma beta-carotene was inversely correlated with the relative body weight, but not with plasma total lipids. In contrast, the plasma alpha-tocopherol concentration was correlated with plasma total lipids, but not with the severity of obesity. Both the beta-carotene/plasma total lipids ratio and the alpha-tocopherol/plasma total lipids ratio were decreased in hyperlipidemic children, while there was a slight increase of the plasma retinol concentration. There was a marked elevation of the plasma beta-carotene concentration and a reduction of the alpha-tocopherol concentration corresponding to the changes of plasma lipids with diet and exercise. We conclude that different kinetics of the fat-soluble vitamins such as beta-carotene and alpha-tocopherol exists during dieting and exercise in obese children.
authors.affiliation: Department of Pediatrics, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka 569-8686, Japan. ped030@poh.osaka-med.ac.jp
authors.forename: Takao
authors.initials: T
authors.lastname: Morinobu
authors.forename: Takuji
authors.initials: T
authors.lastname: Murata
authors.forename: Ryuzo
authors.initials: R
authors.lastname: Takaya
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tamai
mesh_terms: D000293:Adolescent; D001835:Body Weight; D002648:Child; D004038:Diet, Reducing; D015444:Exercise; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood; D008055:Lipids / Q000097:blood; D008297:Male; D009752:Nutritional Status; D009765:Obesity / Q000097:blood* / Q000628:therapy; D014801:Vitamin A / Q000097:blood*; D015431:Weight Loss; D024502:alpha-Tocopherol / Q000097:blood*; D019207:beta Carotene / Q000097:blood*
chemical_list: D008055:Lipids; D019207:beta Carotene; D014801:Vitamin A; D024502:alpha-Tocopherol