Manipulations in maternal environment reverse periodontitis in genetically predisposed rats.
The predisposition to develop periodontitis is partly genetically determined in humans as well as in animals. Here we demonstrate, however, that early manipulations in the maternal environment of an animal (rat) model of periodontitis can fully reverse the genetic predisposition to develop periodontitis at adult age.
Sluyter
Frans
F
SGDP Research Centre, Institute of Psychiatry, London, United Kingdom.
Breivik
Torbjørn
T
Cools
Alexander
A
D000818:Animals; D004198:Disease Susceptibility / Q000209:etiology; D005260:Female; D020022:Genetic Predisposition to Disease; D008297:Male; D008426:Maternal Deprivation; D010518:Periodontitis / Q000209:etiology* / Q000517:prevention & control; D051381:Rats