Non-tuberculous mycobacterial pulmonary infections.
Pulmonary disease due to EM occurs worldwide, and its prevalence has increased as a consequence of the HIV pandemic. It is not often detected in the tropics owing to a lack of laboratory facilities, but when sought it has been found. In addition to HIV infection certain occupations such as mining render the work force more susceptible to disease and calls for a revision of working conditions. Resolution by therapy can be achieved in many cases. As the prevalence of TB diminishes worldwide--and hopefully it will in the wake of the resurgence of interest and the widespread application of the World Health Organization's Directly Observed Therapy Short Course (DOTS) strategy--disease due to EM will become relatively more important and will necessitate revised strategies in clinical, microbiological, and public health approaches to mycobacterial disease.
Zumla
Alimuddin I
AI
Centre for Infectious Diseases and International Health, University College London, Windeyer Institute, Room G41, 46 Cleveland Street, London W1P 6DB, UK. a.zumla@ucl.ac.uk
Grange
John
J
D000328:Adult; D004781:Environmental Exposure; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D009170:Nontuberculous Mycobacteria / Q000472:pathogenicity; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D012307:Risk Factors; D014774:Virulence