[Celiac disease--a diagnostic and scientific challenge].
It is possible that Denmark has a high proportion of patients with undiagnosed coeliac disease in the general population and in such risk groups as patients with autoimmune endocrinological and neurological disorders. An active diagnostic strategy, with screening of patients at risk is proposed. Several gliadin epitopes that might be pathogenetically important are described. Tissue transglutaminase is an autoantigen and a deamidating factor in vitro.
Skovbjerg
Hanne
H
Intern medicinsk klinik, Medicinsk Center, H:S Amager Hospital, DK-2300 København S.
Sjöström
Hans
H
Norén
Ove B
OB
D001327:Autoimmune Diseases / Q000175:diagnosis; D002446:Celiac Disease / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology; D003718:Denmark / Q000453:epidemiology; D000939:Epitopes / Q000235:genetics; D020022:Genetic Predisposition to Disease; D005903:Gliadin / Q000235:genetics / Q000276:immunology; D006801:Humans; D008403:Mass Screening; D012307:Risk Factors
D000939:Epitopes; D005903:Gliadin