title: Effect of exercise testing protocol on the relationship between minute ventilation and carbon dioxide production.
abstract: BACKGROUND
  The effect of exercise protocol on the slope of the relationship between minute ventilation and carbon dioxide production (deltaVE/deltaVCO2) has not fully been studied.
  
  
  METHODS
  Twenty-five healthy volunteers performed two sessions of incremental bicycle exercise, one with a rapidly increasing staged (RIS: 25W every minute) protocol and another with a slowly increasing staged (SIS: 25W every 3 minutes) protocol to calculate the deltaVE/deltaVCO2. Six of the subjects also participated in sessions of steady state exercise (SSE) test various work rates.
  
  
  RESULTS
  The deltaVE/deltaVCO2 was significantly lower when the RIS protocol was used than when the SIS protocol was used (23.3 +/- 2.3 vs. 24.9 +/- 1.8, p < 0.001). Data from the subjects who also underwent SSE sessions revealed that the deltaVE/deltaVCO2 from the SSE protocols was greater than that from the RIS protocol and identical with that from the SIS protocol (125.1 +/- 3.7. 20.6 +/- 1.7, and 24.0 +/- 2.7, respectively, p < 0.05), while arterial partial pressure of carbon dioxide during exercise was not different between the protocols (43.0 +/- 3.3. 39.9 +/- 2.1, and 40.8 +/- 2.6, respectively, n.s.). C ONCLUSIONS: Care must be taken in the interpretation of the values of deltaVE/deltaVCC2, as they are influenced by the difference in exercise protocol.
authors.affiliation: Department of Pediatrics, Nagoya University School of Medicine.
authors.forename: Masanobu
authors.initials: M
authors.lastname: Ikoma
authors.forename: Reizo
authors.initials: R
authors.lastname: Bab
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Mochiduki
authors.forename: Suketsune
authors.initials: S
authors.lastname: Iwagaki
mesh_terms: D000293:Adolescent; D000328:Adult; D002245:Carbon Dioxide / Q000097:blood / Q000378:metabolism; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D012143:Respiratory Physiological Phenomena
chemical_list: D002245:Carbon Dioxide