Structure of a New Glucan from Cynanchum panilatum (Bunge) Kitagawa.
A polysaccharide was purified from a traditional Chinese drug, "Xu-Chang-Qing" (Cynanchum panilatum (Bunge) Kitagawa), and its molecular weight was estimated to be 1.5x10(4) by HPLC method. Its specific rotation [alpha](D) was 151.4 deg; (0.96, H(2)O). Sugar composition analysis indicated this polysaccharide was composed only of glucose. Methylation analysis, partially hydrolysis, acetolysis, IR and NMR data showed that its main chain was composed of alpha-D 1,4 linked glucosyl residues and its side chains were composed of alpha-D 1,4 and alpha-D 1,6 linked glucosyl residues. There was one branch located at O-6 of the glucosyl residue in every repeating unit containing five-glucosyl residues.
Wang
Shun-Chun
SC
Shanghai Institute of Materia Medica, the Chinese Academy of Sciences, Shanghai 200031, China. jnfang@mail.shcnc.ac.cn
He
Wei
W
Fang
Ji-Nian
JN