New tropane alkaloids from Erythroxylum moonii.
Four new tropane alkaloids were isolated from the leaves of Erythroxylum moonii and identified as 3 alpha-isobutyryloxy-7 beta-hydroxynortropane (1), 3 alpha-hydroxy-7 beta-phenylacetoxynortropane (2), 3 alpha-cis-cinnamoyloxytropane (3), and 3 alpha-hydroxy-6 beta-(3'-hydroxy-2'-methyl-3'-phenylpropionyloxy)-7 beta-hydroxytropane (4). Other alkaloids isolated for the first time from E. moonii were 3 alpha-benzoyloxytropane, 3 alpha-phenylacetoxytropane, 3 alpha-trans-cinnamoyloxytropane, and 3 alpha-phenylacetoxy-6 beta,7 beta-dihydroxynortropane. The structures of compounds 1-4 were elucidated by spectroscopic methods.
Khattak
Khanzadi Fatima
KF
International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. khattakkf@yahoo.com
Atta-ur-Rahman
Choudhary
Mohammad Iqbal
MI
Hemalal
K D
KD
Tillekeratne
L M
LM
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification*; D030921:Erythroxylaceae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013188:Sri Lanka; D013237:Stereoisomerism; D014326:Tropanes / Q000737:chemistry* / Q000302:isolation & purification*
D000470:Alkaloids; D014326:Tropanes