One-year rehospitalization rates of patients discharged on atypical versus conventional antipsychotics.
This study examined one-year rehospitalization rates for patients who were discharged from Austin State Hospital between August 1, 1997, and July 31, 1998, while taking olanzapine, risperidone, or a conventional antipsychotic. Time to readmission was measured by the product-limit formula. Although conventional antipsychotics were associated with a lower rehospitalization rate, no significant difference in the one-year rehospitalization rate was observed between the groups. At 180 days after initial discharge, the patients who received olanzapine had a higher rate of rehospitalization than patients who were taking conventional antipsychotics. Conventional antipsychotics were associated with a lower one-year rehospitalization rate than risperidone or olanzapine.
Patel
Nick C
NC
Austin State Hospital, Texas Department of Mental Health and Mental Retardation, and the College of Pharmacy of the University of Texas, Austin, Texas 78712, USA.
Dorson
Peter G
PG
Edwards
Nancy
N
Mendelson
Stacy
S
Crismon
M Lynn
ML
D000293:Adolescent; D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001569:Benzodiazepines; D006801:Humans; D008875:Middle Aged; D000077152:Olanzapine; D010359:Patient Readmission; D010890:Pirenzepine / Q000031:analogs & derivatives / Q000627:therapeutic use*; D011618:Psychotic Disorders / Q000188:drug therapy*; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*; D013997:Time Factors
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D018967:Risperidone; D000077152:Olanzapine