Pregnancy complicated with lactate dehydrogenase M-subunit deficiency: the first case report.
A woman with lactate dehydrogenase M-subunit deficiency underwent two cesarean sections because of the risk of dystocia due to decreased adenosine triphosphate production in anaerobic glycolysis including uterine muscles. Frequent pains with increased serum pyruvate levels were observed during the third trimester of her pregnancies.
Anai
Takanobu
T
School of Nursing, Department of Obstetrics and Gynecology, Oita Medical University, Japan. ANAITA@oita-med.ac.jp
Urata
Kenichirou
K
Tanaka
Yuichirou
Y
Miyakawa
Isao
I
D015746:Abdominal Pain; D000255:Adenosine Triphosphate / Q000378:metabolism; D000293:Adolescent; D002585:Cesarean Section; D004420:Dystocia; D005260:Female; D006019:Glycolysis; D006801:Humans; D007527:Isoenzymes / Q000172:deficiency; D007770:L-Lactate Dehydrogenase / Q000172:deficiency*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000201:enzymology*; D011256:Pregnancy Outcome; D019289:Pyruvic Acid / Q000097:blood; D014599:Uterus / Q000378:metabolism
D007527:Isoenzymes; D019289:Pyruvic Acid; D000255:Adenosine Triphosphate; D007770:L-Lactate Dehydrogenase