[Neurogenetics in Parkinson's disease].
The pathogenesis of Parkinson's disease, a progressive degenerative disorder of the central nervous system, remains obscure. 20% of cases are familial. The disorder may be due to a combination of genetic and environmental factors. Some monogenic forms of Parkinson's disease have been described. Many genetic studies explore whether a candidate gene may confer an increased risk for this disease. The search for a genetic susceptibility may lead to establish a preventive therapy.
Stefanache
F
F
Facultatea de Medicină, Clinica I Neurologie, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Hodorog
D
D
Cuciureanu
D
D
D020022:Genetic Predisposition to Disease; D006801:Humans; D009419:Nerve Tissue Proteins / Q000235:genetics*; D010300:Parkinson Disease / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype; D012307:Risk Factors; D051843:Synucleins
D009419:Nerve Tissue Proteins; D051843:Synucleins