title: Death following spontaneous recovery from cardiopulmonary arrest in a hospital mortuary: 'Lazarus phenomenon' in a case of alleged medical negligence.
abstract: We report a possibly first forensic autopsy case of death following a spontaneous recovery from cardiopulmonary arrest (CPA) after clinical declaration of death: 'Lazarus phenomenon'. A 65-year-old male with congenital deafness and dumbness was found unconscious in his room at a public home. During pre-hospital and clinical resuscitation including defibrillation and medications for about 35 min, CPA persisted under electrocardiographic (ECG) monitoring and therefore, his death was pronounced. However, about 20 min later, a police officer who had been called for the postmortem investigation found the patient moving in the mortuary. The patient subsequently showed typical ECG signs and laboratory findings of early inferior wall myocardial infarction and died 4 days later. The forensic autopsy, due to alleged medical negligence, revealed myocardial infarction with thrombotic occlusion of the right coronary artery and secondary hypoxic brain damage. The present case and the related clinical literature suggest that, especially in cases of acute myocardial infarction in elderly patients, a careful observation to confirm death after discontinuation of resuscitation is recommended to provide appropriate medical care, irrespective of the quality or duration of advanced life supporting efforts.
authors.affiliation: Department of Legal Medicine, Osaka City University Medical School, Asahi-machi 1-4-3, Abeno, Japan. legalmed@med.osaks-cu.ac.jp
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Maeda
authors.forename: Masaki Q
authors.initials: MQ
authors.lastname: Fujita
authors.forename: Bao-Li
authors.initials: BL
authors.lastname: Zhu
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Yukioka
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Shindo
authors.forename: Li
authors.initials: L
authors.lastname: Quan
authors.forename: Kaori
authors.initials: K
authors.lastname: Ishida
mesh_terms: D000368:Aged; D016887:Cardiopulmonary Resuscitation; D004562:Electrocardiography; D017809:Fatal Outcome; D005554:Forensic Medicine; D006323:Heart Arrest / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D019300:Medical Errors