title: Prevalence of systolic hypertension in cats with chronic renal failure at initial evaluation.
abstract: OBJECTIVE
  To determine prevalence of systolic hypertension and associated risk factors in cats with chronic renal failure evaluated in first-opinion practice.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  103 cats with chronic renal failure.
  
  
  METHODS
  Systolic arterial blood pressure (SABP) was measured with a noninvasive Doppler technique, and cats that had SABP > 175 mm Hg on 2 occasions or that had SABP > 175 mm Hg and compatible ocular lesions were classified as hypertensive. Information from the history (previous treatment for hyperthyroidism, age), physical examination (sex, body weight), routine plasma biochemical analyses (creatinine, cholesterol, potassium, sodium, chloride, and calcium concentrations), and thyroid status were evaluated as potential risk factors for systolic hypertension. Variables associated with systolic hypertension were evaluated by use of logistic regression.
  
  
  RESULTS
  20 (19.4%; 95% confidence interval, 13 to 28%) cats had systolic hypertension. Plasma potassium concentration was significantly and inversely associated with systolic hypertension.
  
  
  CONCLUSIONS
  Prevalence of systolic hypertension, although clinically important, was lower than that reported previously. The cause of the inverse association between systolic hypertension and plasma potassium concentration is not yet known.
authors.affiliation: Department of Veterinary Basic Science, Royal Veterinary College, London, UK.
authors.forename: Harriet M
authors.initials: HM
authors.lastname: Syme
authors.forename: Penney J
authors.initials: PJ
authors.lastname: Barber
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Markwell
authors.forename: Jonathan
authors.initials: J
authors.lastname: Elliott
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002371:Cat Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D002415:Cats; D004739:England / Q000453:epidemiology; D005260:Female; D006977:Hypertension, Renal / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*; D006980:Hyperthyroidism / Q000175:diagnosis / Q000662:veterinary; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D011188:Potassium / Q000097:blood; D015995:Prevalence; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D013599:Systole
chemical_list: D011188:Potassium