title: Synthesis of zwitterionic compounds: fully saturated pyrimidinylium and 1,3-diazepinylium derivatives via the novel rearrangement of 3-oxobutanoic acid thioanilide derivatives.
abstract: An unusual rearrangement following cyclization of 2-anilino-2-ethoxy-3-oxothiobutanoic acid with aliphatic 1,3- as well as 1,4-diamine leads to zwitterionic derivatives of 2-hydroxypropanoic acid. Moreover, with aromatic 1,2-diamines, fused heterocyclic systems such as pteridine, quinoxaline, and pyrido[2,3-b]pyrazine are obtained.
authors.affiliation: Department of Organic Chemistry, Jagiellonian University, and Regional Laboratory of Physicochemical Analyses and Structural Research, ul. Ingardena 3, PL 30-060 Kraków, Poland. zaleska@chemia.uj.edu.pl
authors.forename: Barbara
authors.initials: B
authors.lastname: Zaleska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Bazanek
authors.forename: Robert
authors.initials: R
authors.lastname: Socha
authors.forename: Marcin
authors.initials: M
authors.lastname: Karelus
authors.forename: Jacek
authors.initials: J
authors.lastname: Grochowski
authors.forename: Paweł
authors.initials: P
authors.lastname: Serda