Are infantile seborrheic and atopic dermatitis clinical variants of the same disease?
BACKGROUND
The relationship between infantile seborrheic dermatitis (ISD) and infantile atopic dermatitis (IAD) is controversial.


METHODS
Ninety-six children aged 2-12 months diagnosed with atopic dermatitis and a comparable control group of healthy children were evaluated. Demographic data, personal history of ISD and personal or family history of atopy was considered in both groups.


RESULTS
A personal history of ISD was found in 49% of IAD cases and in 17% of controls (P < 0.05).


CONCLUSIONS
Our result and those of the literature do not demonstrate a relationship between ISD and IAD. However, a number of cases of AD have an ISD-like clinical picture. It is probable that ISD is a syndrome and not a disease.
Moises-Alfaro
Celia B
CB
Department of Dermatology, Institute for Child Health, Lima, Peru.
Caceres-Rios
Hector W
HW
Rueda
Monica
M
Velazquez-Acosta
Alvaro
A
Ruiz-Maldonado
Ramon
R
D000367:Age Factors; D003876:Dermatitis, Atopic / Q000150:complications* / Q000235:genetics / Q000473:pathology*; D012628:Dermatitis, Seborrheic / Q000150:complications* / Q000235:genetics / Q000473:pathology*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D013577:Syndrome