title: Chronic disseminated Trichosporon asahii infection in a leukemic child.
abstract: We report a case of chronic disseminated Trichosporon asahii infection in a leukemic child. Administration of amphotericin B lipid complex resulted in rapid control and improvement of the initial infection but failed to prevent the development of chronic disseminated disease. Cure was achieved after treatment was changed to a 20-month course of itraconazole. This case report demonstrates that Trichosporon species can cause chronic disseminated disease with a pattern similar to that of disease caused by Candida species.
authors.affiliation: Institut de Parasitologie et de Pathologie Tropicale, Faculté de Médecine, Hôpital de Hautepierre, 67000 Strasbourg, France.
authors.forename: M H
authors.initials: MH
authors.lastname: Meyer
authors.forename: V
authors.initials: V
authors.lastname: Letscher-Bru
authors.forename: J
authors.initials: J
authors.lastname: Waller
authors.forename: P
authors.initials: P
authors.lastname: Lutz
authors.forename: L
authors.initials: L
authors.lastname: Marcellin
authors.forename: R
authors.initials: R
authors.lastname: Herbrecht
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D002908:Chronic Disease; D006801:Humans; D007938:Leukemia / Q000188:drug therapy / Q000382:microbiology*; D008107:Liver Diseases / Q000382:microbiology; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy; D014250:Trichosporon / Q000187:drug effects / Q000302:isolation & purification