title: [The effectiveness of the long-term treatment with pranlukast in pediatric patients with mild to moderate asthma].
abstract: To investigate the efficacy of the long-term treatment with pranlukast, a specific cysteinyl leukotriene receptor antagonist, in pediatric patients with mild to moderate asthma, 77 pediatric asthmatic patients who received pranlukast for up to 36 months (mean duration, 13 months) were evaluated retrospectively. Treatment with pranlukast resulted in improvements from the pretreatment baseline in asthma attacks per month, episodes of hospitalization, and episodes of intravenous amynophiline treatment on emergent clinic visits. The percentage of responders who had marked or moderate improvements in the above-mentioned parameters of asthma control was 79%. In conclusion, pranlukast caused significant improvements in long-term asthma control in pediatric patients with mild to moderate asthma.
authors.affiliation: Department of Pediatrics, Kishiwada City Hospital.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Hata
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Shiota
authors.forename: Yoshika
authors.initials: Y
authors.lastname: Tamura
authors.forename: Maki
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Kayo
authors.initials: K
authors.lastname: Ohmura
authors.forename: Shiro
authors.initials: S
authors.lastname: Seto
authors.forename: Kenshi
authors.initials: K
authors.lastname: Furusho
mesh_terms: D000293:Adolescent; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D002867:Chromones / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007223:Infant; D020024:Leukotriene Antagonists / Q000008:administration & dosage*; D008297:Male; D012189:Retrospective Studies
chemical_list: D018927:Anti-Asthmatic Agents; D002867:Chromones; D020024:Leukotriene Antagonists; C047681:pranlukast