title: [Clinical and biological study of acute diarrhea with mixed etiology in 48 patients].
abstract: OBJECTIVE
  The study of incidence, clinical manifestation and treatment of acute diarrhea with mixed etiology.
  
  
  METHODS
  Study of 48 patients with acute diarrhea with mixed etiology admitted in the Hospital of Infectious Diseases of Iaşi during 1995-1998.
  
  
  RESULTS
  12 cases (24%) were mixed bacterial infections with the following microorganisms associations: Salmonella + Shigella (10 cazuri); Salmonella + Yersinia enterocolitica (1 case); Salmonella + Rotavirus (1 case). 16 cases (44%) had mixed digestive infections with parasites, in double or triple associations: Giardia intestinalis + Ascaris lumbricoides (10 cases); Giardia intestinalis + Ascaris lumbricoides + Entamoeba coli (1 case); Giardia intestinalis + Enterobius vermicularis (3 cases); Ascaris lumbricoides + Trichiuris trichiura (2 cases). The rest of 20 cases presented mixed infections with bacteria and parasites: Salmonella + Rotavirus + Giardia (2 cases), Salmonella + Shigella + Giardia intestinalis or Ascaris lumbricoides (6 cases), Salmonella + Giardia intestinalis (8 cases); Salmonella + Entamoeba coli (3 cases); Shigella + Trichiura trichiuris + Entamoeba coli (1 case). The majority was male patients from rural areas with age between 5 month and 56 years, the majority being children, 4 cases were found in immunosupressed patients. The clinical symptomatology was dominated by diarrheal syndrome (100%) and the diagnosis was established by clinical characters and confirmed by coproculture and parasitologic exam. The ethiological therapy was guided by antibiogram, in the majority of cases we used fluorochinolones (associated with ceftriaxone in severe cases), together with antiparasitic medications.
  
  
  CONCLUSIONS
  In this study predominated the bacterial and parasitic infections, most frequently being isolated Salmonella, Shigella and Giardia intestinalis; the therapy associated fluorochinolones with antiparasitic medication.
authors.affiliation: Clinica Boli Infecţioase, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi.
authors.forename: C
authors.initials: C
authors.lastname: Luca
authors.forename: V
authors.initials: V
authors.lastname: Luca
authors.forename: T
authors.initials: T
authors.lastname: Turcu
authors.forename: D
authors.initials: D
authors.lastname: Mihalache
authors.forename: R
authors.initials: R
authors.lastname: Fîntînaru
authors.forename: I
authors.initials: I
authors.lastname: Teodorescu
authors.forename: E
authors.initials: E
authors.lastname: Miftode
authors.forename: C
authors.initials: C
authors.lastname: Corcaci
authors.forename: D
authors.initials: D
authors.lastname: Leca
authors.forename: M
authors.initials: M
authors.lastname: Hurmuzache
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000209:etiology*; D005243:Feces / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D005260:Female; D006801:Humans; D015994:Incidence; D007411:Intestinal Diseases, Parasitic / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D012400:Rotavirus Infections / Q000453:epidemiology; D012480:Salmonella Infections / Q000453:epidemiology