title: Dysmetabolic syndrome: multiple risk factors for premature adult disease in an adolescent girl.
abstract: The clinical diagnosis of dysmetabolic syndrome in an adult defines a patient with abnormal glucose metabolism (or diabetes), hypertension, hyperlipidemia, and obesity. This disorder accelerates atherosclerosis and significantly raises the risk for cardiovascular events. With the marked rise in the prevalence of obesity in childhood, obesity-linked risk factors are being expressed at young ages. The case of a 12-year-old girl with dysmetabolic syndrome is described and discussed. Emerging clinical data now indicate that the presence of 1 risk factor for cardiovascular disease in an overweight child should prompt screening for additional clinical abnormalities, with the aim of finding treatable disorders.
authors.affiliation: Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. bonita.falkner@mail.tju.edu
authors.forename: Bonita
authors.initials: B
authors.lastname: Falkner
authors.forename: Sandra
authors.initials: S
authors.lastname: Hassink
authors.forename: Judith
authors.initials: J
authors.lastname: Ross
authors.forename: Samuel
authors.initials: S
authors.lastname: Gidding
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002318:Cardiovascular Diseases / Q000175:diagnosis; D002648:Child; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000175:diagnosis / Q000453:epidemiology; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome; D009765:Obesity / Q000175:diagnosis / Q000453:epidemiology; D012307:Risk Factors