title: Dynamic time-resolved contrast-enhanced two-dimensional MR projection angiography of the pulmonary circulation: standard technique and clinical applications.
abstract: OBJECTIVE
  Time-resolved pulmonary two-dimensional MR projection angiography is a fast acquisition technique that allows the generation of dynamic projection angiograms by a method similar to that used to generate digital subtraction angiograms. MR images are obtained after subtracting the mask defined at the beginning of the sequence from later images, thus generating time-resolved continuous projection angiograms that depict the passage of a bolus through the pulmonary circulation. This article describes the application of this novel technique in three patients with pathologic conditions not previously described with this modality and two control subjects.
  
  
  CONCLUSIONS
  The analysis of the findings on dynamic time-resolved contrast-enhanced two-dimensional MR projection angiography shows that this technique is useful not only in revealing morphologic changes associated with pulmonary disorders but also in following the passage of the bolus through the cardiopulmonary circulation. The latter capability allows qualitative detection of normal or abnormal pathways and thus is potentially of value in the assessment of several pulmonary disorders.
authors.affiliation: Department of Radiology, University Hospital Basel, Petersgraben 4, 4051 Basel, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Sonnet
authors.forename: C H
authors.initials: CH
authors.lastname: Buitrago-Téllez
authors.forename: K
authors.initials: K
authors.lastname: Scheffler
authors.forename: R
authors.initials: R
authors.lastname: Strecker
authors.forename: G
authors.initials: G
authors.lastname: Bongartz
authors.forename: J
authors.initials: J
authors.lastname: Bremerich
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D011652:Pulmonary Circulation / Q000502:physiology*; D011667:Pulmonary Veins / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D011859:Radiography; D013997:Time Factors
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA