title: Effect of major depression on cognitive performance among treatment-seeking adolescents.
abstract: We investigated the association between cognitive performance and major depressive disorder (MDD) in adolescents seeking outpatient treatment. We used several tests comparing cognitive capacities between 16 adolescents with MDD and 25 adolescents not diagnosed as suffering from psychiatric illness according to the Structured Clinical Interview for DSM-III-R (SCID). No difference in neuropsychological test performance was found between adolescents with MDD and those without psychiatric diagnosis. Logistic regression analysis showed the only independent factor associated with MDD to be Emotional Tone (S2; odds ratio 1.13). The specific effects of MDD on the adolescents were restricted to the emotional area and were expressed as a broad deterioration in psychosocial functioning.
authors.affiliation: Department of Psychiatry, Kuopio University Hospital, P.O.Box 1777, Finland.
authors.forename: Veijo
authors.initials: V
authors.lastname: Korhonen
authors.forename: Eila
authors.initials: E
authors.lastname: Laukkanen
authors.forename: Risto
authors.initials: R
authors.lastname: Antikainen
authors.forename: Sirkka
authors.initials: S
authors.lastname: Peiponen
authors.forename: Johannes
authors.initials: J
authors.lastname: Lehtonen
authors.forename: Heimo
authors.initials: H
authors.lastname: Viinamäki
mesh_terms: D000293:Adolescent; D000553:Ambulatory Care; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000523:psychology* / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010342:Patient Acceptance of Health Care; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index