Intractable epilepsy in vascular congenital hemiparesis: clinical features and surgical options.
Forty-one patients with vascular congenital hemiplegia and intractable epilepsy were reviewed. Most had severe hemiparesis, mental retardation, porencephaly, and focal epilepsy. Thirty-three were considered surgical candidates and 25 underwent surgery. Seizure freedom and significant seizure reduction were achieved in 12 of 13 patients after functional hemispherectomy, 4 of 6 after temporal lobectomy, 2 of 2 with extratemporal focal resections, 1 of 3 with corpus callosotomy, and 1 with porencephalic cyst drainage.
Carreño
M
M
Departments of Neurology, Cleveland Clinic Foundation, OH 44195, USA.
Kotagal
P
P
Perez Jiménez
A
A
Mesa
T
T
Bingaman
W
W
Wyllie
E
E
D000293:Adolescent; D000328:Adult; D002648:Child; D018572:Disease-Free Survival; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000473:pathology / Q000601:surgery*; D006429:Hemiplegia / Q000151:congenital* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011184:Postoperative Period; D012189:Retrospective Studies; D016896:Treatment Outcome