Thrombospondin-1 may modulate keloid formation through up-regulation of the matrix-associated plasminogen/plasmin system.
Centeno
Robert F
RF
Albo
Daniel
D
Rothman
Vicki L
VL
Granick
Mark S
MS
Tuszynski
George P
GP
D002478:Cells, Cultured; D005109:Extracellular Matrix / Q000473:pathology / Q000502:physiology*; D005341:Fibrinolysin / Q000502:physiology*; D005347:Fibroblasts / Q000473:pathology / Q000502:physiology; D006801:Humans; D007627:Keloid / Q000473:pathology / Q000503:physiopathology*; D010958:Plasminogen / Q000502:physiology*; D019700:Thrombospondin 1 / Q000502:physiology*; D015854:Up-Regulation / Q000502:physiology
D019700:Thrombospondin 1; D010958:Plasminogen; D005341:Fibrinolysin