A case of cutaneous ganglioneuroma developing within a lesion of seborrheic keratosis.
A 67-year-old man noticed on the abdominal skin a coin-sized verrucous plaque, in which a small granulation-like lesion developed several weeks before the first consultation at our clinic. The histology of the biopsied granulation-like lesion showed a well demarcated, but not associated with the collagenous capsule, mass of proliferating eosinophilic cells, consisting of intervening spindle-shaped Schwann cells and mature ganglion cells scattered in the tumor nest. We diagnosed this tumor nest as a ganglioneuroma, which rarely develops in the skin tissue. The simply resected surrounding verrucous lesion was histologically seborrheic keratosis.
Ohno
Sayoko
S
Ohno Dermatologic Clinic, Nara, Japan.
Horiguchi
Yuji
Y
Shintaku
Masayuki
M
D000368:Aged; D001707:Biopsy, Needle; D005500:Follow-Up Studies; D005729:Ganglioneuroma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D017492:Keratosis, Seborrheic / Q000473:pathology* / Q000601:surgery; D008297:Male; D011230:Precancerous Conditions / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome