Recent progress in the biology and treatment of Wilms' tumor.
The survival rate of patients with Wilms' tumor has rapidly improved in the last few decades. As we enter into the new millennium, overall survival for all Wilms' tumor patients exceeds 80%. Two large cooperative groups prospectively studied children with nephroblastoma: the National Wilms' Tumor Study Group, and the International Society of Paediatric Oncology. This review details the recent progress in understanding the biology of Wilms' tumor. Advances in clinical management of children with nephroblastoma are also outlined.
Ritchey
M L
ML
Division of Urology, University of Texas-Houston Medical, 6431 Fannin, 6.018, Houston, TX 77030, USA. mritchey@utsurg.med.uth.tmc.edu
D002648:Child; D006801:Humans; D007680:Kidney Neoplasms / Q000503:physiopathology* / Q000628:therapy*; D009396:Wilms Tumor / Q000503:physiopathology* / Q000628:therapy*