Mouthpiece versus facemask for delivery of nebulized salbutamol in exacerbated childhood asthma.
We compared the bronchodilator response to salbutamol (albuterol) delivered by a compressed air nebulizer through a mouthpiece and via a facemask in 18 asthmatic children, to determine the most appropriate delivery method. Patients using a mouthpiece had significantly better mean percent increases in forced expiratory volume in 1 sec (FEV1) and in forced vital capacity (FVC) than those using a facemask 30 min after inhalation (FEV1, 56.4 +/- 32.6% vs. 28.9 +/- 19.1%, FVC: 34.4 +/- 26.4% vs. 7.5 +/- 14.9%, respectively). Nebulized therapy plays an important role in the management of bronchial asthma in children and should be delivered by a mouthpiece whenever possible in cases of exacerbated asthma.
Kishida
Masaru
M
Second Department of Pediatrics, Toho University School of Medicine, Tokyo, Japan. masa1114@polaris.med.toho-u.ac.jp
Suzuki
Istuo
I
Kabayama
Hirohiko
H
Koshibu
Tatsuro
T
Izawa
Masako
M
Takeshita
Yukiko
Y
Kurita
Fumiko
F
Okada
Mari
M
Shinomiya
Noriaki
N
Aoki
Tsugutoshi
T
D000280:Administration, Inhalation; D000293:Adolescent; D000420:Albuterol / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D002648:Child; D004867:Equipment Design; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008397:Masks; D009330:Nebulizers and Vaporizers; D016896:Treatment Outcome
D001993:Bronchodilator Agents; D000420:Albuterol