title: Non-neoplastic demyelinating process mimicking a disseminated malignant brain tumour.
abstract: Non-neoplastic demyelinating processes of the brain with ring enhancing lesions and mass effect on MRI imaging, mimicking malignant brain tumours, are rare phenomena. We document the case of a 32 year old male with clinical, radiological and initial histological findings, suggestive of a malignant brain tumour. Additional investigations confirmed the diagnosis of multiple sclerosis. This case is significant as the lesion could not be easily distinguished from a malignant brain tumour on imaging alone. Cases such as this illustrate the importance of considering a demyelinating process in the differential diagnosis of tumour-like brain lesions.
authors.affiliation: Department of Neurosurgery, Royal Hobart Hospital, Hobart, Tasmania, Australia.
authors.forename: A
authors.initials: A
authors.lastname: Mujic
authors.forename: J
authors.initials: J
authors.lastname: Liddell
authors.forename: A
authors.initials: A
authors.lastname: Hunn
authors.forename: J
authors.initials: J
authors.lastname: McArdle
authors.forename: A
authors.initials: A
authors.lastname: Beasley
mesh_terms: D001254:Astrocytoma / Q000175:diagnosis*; D001706:Biopsy; D001932:Brain Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000188:drug therapy; D013256:Steroids / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D013256:Steroids