Lessons from similarities between SLE and HIV infection.
OBJECTIVE
We attempted to obtain deeper understanding of systemic lupus erythematosus (SLE) and human immunodeficiency virus (HIV) infection through comparative studies between both diseases.


METHODS
For this purpose, we reviewed and discussed lessons from similarities in both diseases based on our own and reported findings in literatures.


RESULTS
Such comparative studies may contribute to the progress in understanding the clinical or pathogenetic features of these diseases.


CONCLUSIONS
Further studies into the relationship between SLE and HIV infection may bring to light important clues to assist in the development of better treatments for each disease.
Sekigawa
I
I
Department of Medicine, Juntendo University Izu-Nagaoka Hospital, 1129 Nagaoka, Izu-Nagaoka-cho, Tagata-gun, Shizuoka, Japan. sekigawa@mtd.biglobe.ne.jp
Okada
M
M
Ogasawara
H
H
Naito
T
T
Kaneko
H
H
Hishikawa
T
T
Iida
N
N
Hashimoto
H
H
D015658:HIV Infections / Q000150:complications / Q000209:etiology* / Q000276:immunology* / Q000821:virology; D006801:Humans; D015994:Incidence; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000209:etiology* / Q000276:immunology* / Q000821:virology; D008954:Models, Biological; D012190:Retroviridae / Q000502:physiology