[A case of malignant lymphoma of the stomach in which preoperative chemotherapy provided a complete response].
We have encountered a case of malignant lymphoma of the stomach in which a complete remission was confirmed in a resected specimen after chemotherapy. A 75-year-old woman complained of vomiting blood. A biopsy from gastric endoscopy indicated malignant lymphoma of diffuse large B-cell type. The patient was assumed to be inoperable due to enlargement of the tumor and lymph node metastasis, and THP-COP chemotherapy was carried out. After four courses of the THP-COP regimen, endoscopic examination revealed a significant tumor reduction. Total gastrectomy and splenectomy with lymph node dissection (D2) were performed after chemotherapy. No tumor cells were detected in any sections of the specimen or regional lymph nodes.
Okumoto
Tatsuo
T
Dept. of Surgery, Himeji St. Mary's Hospital.
Tomiyama
Koji
K
Ino
Hideo
H
Kanaya
Yoshiaki
Y
Maruyama
Shuichiro
S
Otani
Jun
J
Yokoyama
Nobuji
N
Soda
Mitsuhiro
M
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004317:Doxorubicin / Q000031:analogs & derivatives / Q000627:therapeutic use*; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D016393:Lymphoma, B-Cell / Q000188:drug therapy* / Q000601:surgery; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy* / Q000601:surgery; D011239:Prednisolone / Q000627:therapeutic use*; D012074:Remission Induction; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000601:surgery; D014750:Vincristine / Q000627:therapeutic use*
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone