title: Different types of hysterectomy in the radio-surgical treatment of early cervical cancer (FIGO Ib-IIa).
abstract: OBJECTIVE
  Surgery and radiotherapy achieved equivalent results for FIGO stages Ib-IIa invasive cervical carcinoma. The integration of radiotherapy and surgery provided the same results for a selected series of patients without increasing the rate of complications. The aim of the study was to verify if, applying a radio-surgical protocol, the reduction of the surgery extension on the parametrium in one of two consecutive series might achieve the same results in terms of survival and recurrence rates with fewer complications.
  
  
  METHODS
  We analysed actuarial survival (with >10-year follow-up), local control rates and morbidity of 390 patients who had different the kinds of surgery applied in the radio-surgical treatment protocol: Protocol A: brachytherapy plus type III radical hysterectomy vs Protocol B: brachytherapy plus type II radical hysterectomy. Patients were all included in an analysis of complications according to the French-Italian glossary.
  
  
  RESULTS
  Analyses showed no differences in terms of survival, patterns of recurrences and onset time within the two protocols. Urinary complications were more frequent and severe in protocol A vs protocol B (G2: 26.5% vs. 6.1%; G3: 5.3% vs. 3.6%).
  
  
  CONCLUSIONS
  Our study pointed out that the reduction of the surgery extension allowed the same overall survival and relapses with fewer complications particularly in terms of grade of severity.
authors.affiliation: Gynecological Oncology Department, University of Turin, Mauriziano Umberto I Hospital, Institute for Research and Treatment of Cancer (IRCC) Candiolo, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Zola
authors.forename: A
authors.initials: A
authors.lastname: Ferrero
authors.forename: L
authors.initials: L
authors.lastname: Fuso
authors.forename: M E
authors.initials: ME
authors.lastname: Jacomuzzi
authors.forename: A
authors.initials: A
authors.lastname: Magistris
authors.forename: P
authors.initials: P
authors.lastname: Spanu
authors.forename: S
authors.initials: S
authors.lastname: Mazzola
authors.forename: G
authors.initials: G
authors.lastname: Sinistrero
authors.forename: P
authors.initials: P
authors.lastname: Sismondi
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy / Q000145:classification* / Q000379:methods; D007558:Italy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality*; D009367:Neoplasm Staging; D016019:Survival Analysis; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery*