title: Reactive arthritis or chronic infectious arthritis?
abstract: Microbes reach the synovial cavity either directly during bacteraemia or by transport within lymphoid cells or monocytes. This may stimulate the immune system excessively, triggering arthritis. Some forms of ReA correspond to slow infectious arthritis due to the persistence of microbes and some to an infection triggered arthritis linked to an extra-articular site of infection.
authors.affiliation: Rheumatology Department, University Hospital of Strasbourg, France. jean.sibilia@wanadoo.fr
authors.forename: J
authors.initials: J
authors.lastname: Sibilia
authors.forename: F-X
authors.initials: FX
authors.lastname: Limbach
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology; D001170:Arthritis, Infectious / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D016918:Arthritis, Reactive / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology; D002908:Chronic Disease; D004269:DNA, Bacterial / Q000276:immunology; D006801:Humans; D018716:Molecular Mimicry / Q000276:immunology; D000091402:Prohibitins; D013583:Synovial Membrane / Q000276:immunology / Q000382:microbiology; D013585:Synovitis / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D004269:DNA, Bacterial; C000717331:PHB2 protein, human; D000091402:Prohibitins