title: Long-term prognosis in patients with vasculopathic sixth nerve palsy.
abstract: OBJECTIVE
  To better define the long-term prognosis in patients with a vasculopathic sixth nerve palsy (6NP), specifically addressing the degree of recovery and incidence of recurrent similar episodes.
  
  
  METHODS
  Observational case series.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  An outpatient neuroophthalmic practice.
  
  
  METHODS
  Patients with one or more vascular risk factors and an acute, isolated 6NP that spontaneously recovered.
  
  
  METHODS
  Information regarding resolution of the 6NP, subsequent vascular events and recurrent ocular motor nerve palsy was obtained from chart review of follow-up clinic visits, mailed questionnaires and telephone interviews. The duration of follow-up ranged from 2 to 13 years.
  
  
  METHODS
  Resolution of 6NP (complete or incomplete) and incidence of recurrent ocular motor nerve palsy.
  
  
  RESULTS
  Fifty-nine patients were identified with a mean age of 65.3 years +/- 11.6 (range 34-90 years). Fifty-one patients (86%) experienced complete resolution of their first episode of vasculopathic 6NP and eight patients (14%) had incomplete resolution. A subsequent episode of ocular motor mononeuropathy occurred in 18 of 59 (31%) patients. The number of recurrences ranged from one (in 14 patients) to four (in one patient). There was no association between any risk factor and recurrence of ocular motor nerve palsy. Similarly, incomplete resolution of the vasculopathic 6NP was not associated with any risk factor.
  
  
  CONCLUSIONS
  Patients with a vasculopathic 6NP usually have complete resolution of their ophthalmoplegia, but nearly one third of patients in our study later experienced at least one episode of recurrent vasculopathic ocular motor nerve palsy.
authors.affiliation: Associated Vitreo-Retinal and Uveitis Consultants, Indianapolis, Indiana, USA.
authors.forename: Scott K
authors.initials: SK
authors.lastname: Sanders
authors.forename: Aki
authors.initials: A
authors.lastname: Kawasaki
authors.forename: Valerie A
authors.initials: VA
authors.lastname: Purvin
mesh_terms: D020434:Abducens Nerve Diseases / Q000209:etiology / Q000503:physiopathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015840:Oculomotor Nerve Diseases / Q000503:physiopathology; D009886:Ophthalmoplegia / Q000503:physiopathology; D011379:Prognosis; D012008:Recurrence; D012075:Remission, Spontaneous; D012189:Retrospective Studies; D012307:Risk Factors; D014652:Vascular Diseases / Q000150:complications / Q000503:physiopathology*