title: Automated analysis of feline platelets in whole blood, including platelet count, mean platelet volume, and activation state.
abstract: A new whole-blood flow cytometric method has been developed for counting and sizing platelets in samples from cats, a species in which platelet and red blood cell sizes overlap significantly. The method is a modified version of the two-angle laser light scattering technology used by Bayer H*System hematology analyzers. The new method provided accurate platelet counts and mean platelet volumes (MPV, fl) for cats. The method also measured mean platelet component concentration (MPC, g/dl), a parameter which was shown to be sensitive to platelet activation state, and which decreased in value as activation progressed.
authors.affiliation: Bayer Diagnostics Division, 511 Benedict Ave., Tarrytown, NY 10591, USA.
authors.forename: David
authors.initials: D
authors.lastname: Zelmanovic
authors.forename: Edward J.
authors.initials: EJ
authors.lastname: Hetherington