Juvenile human T lymphotropic virus type 1-associated myelopathy.
We report the cases of 5 adolescents with human T lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis, acquired in all but 1 case from the mother. The first symptom in all patients was difficulty in running, which was present for many years before the final diagnosis was made. Follow-up showed an indolent progression, regardless of treatment strategy.
Araújo
Alexandra P Q C
AP
Child Neurology Unit, Federal University of Rio de Janeiro, Rio de Janeiro, RJ 22640-100, Brazil. alexprufer@hotmail.com
Fontenelle
Lucia M C
LM
Pádua
Paula A B
PA
Maia Filho
Heber S
HS
Araújo
Abelardo de Q C
Ade Q
D000293:Adolescent; D001942:Breast Feeding / Q000009:adverse effects; D002648:Child; D018450:Disease Progression; D005260:Female; D015481:HTLV-I Antibodies / Q000097:blood / Q000134:cerebrospinal fluid; D015368:Human T-lymphotropic virus 1 / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D015493:Paraparesis, Tropical Spastic / Q000097:blood / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy; D017211:Treatment Failure
D015481:HTLV-I Antibodies