title: Lymphoepithelioma-like carcinoma of oral cavity: report of three cases and literature review.
abstract: Lymphoepithelioma-like carcinoma is a rare tumour in the oral cavity and is characterized histologically by non-keratinizing, undifferentiated squamous cell carcinoma with lymphocytic infiltration. Three consecutive cases of intraoral lymphoepithelioma-like carcinoma are reported. A review of the literature reveals a similar biological behaviour to that of nasopharyngeal lymphoepithelioma: a high incidence of cervical nodal spread and remarkable radiosensitivity. Chemotherapy should be considered when nodal or distant metastases are present. The association of the Epstein-Barr virus with this tumour remains unclear but our experience suggests a positive correlation in Chinese individuals.
authors.affiliation: Department of Surgery, United Christian Hospital, Kowloon, Hong Kong.
authors.forename: T L
authors.initials: TL
authors.lastname: Chow
authors.forename: T K
authors.initials: TK
authors.lastname: Chow
authors.forename: Y H
authors.initials: YH
authors.lastname: Lui
authors.forename: W M
authors.initials: WM
authors.lastname: Sze
authors.forename: N W F
authors.initials: NW
authors.lastname: Yuen
authors.forename: S P Y
authors.initials: SP
authors.lastname: Kwok
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000821:virology; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006723:Hong Kong; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology / Q000821:virology; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology* / Q000821:virology; D010157:Palatal Neoplasms / Q000473:pathology / Q000821:virology; D010160:Palate, Soft