title: Increased nuchal translucency and pathological ductus venosus flow: two cases of TRAP sequence with different outcomes.
abstract: Twin reversed arterial perfusion (TRAP) sequence develops in 1% of monozygotic twins. One normal twin (donor) provides circulation for itself and for a more or less incomplete twin (recipient) with a high incidence of mortality in the donor twin. However, if the condition is detected and treated early, one twin or two triplets may survive. The study of TRAP sequence helps to better understand the pathophysiological pathways of this condition. We present two cases of TRAP sequence seen in our center with different courses. In these cases the increased nuchal translucency thickness and the pathological ductus venosus flow pattern may have been prognostic of the pregnancy outcome.
authors.affiliation: Praxis für pränatale Dianostik und feto-maternale Medizin, Ludwigsburg, Germany. z760smf@z.zgs.de
authors.forename: H
authors.initials: H
authors.lastname: Meyberg
authors.forename: C
authors.initials: C
authors.lastname: Gross
mesh_terms: D000328:Adult; D004200:Diseases in Twins; D004373:Ductus Arteriosus / Q000503:physiopathology / Q000648:ultrastructure*; D005260:Female; D005330:Fetofetal Transfusion / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005333:Fetus / Q000098:blood supply*; D006801:Humans; D009333:Neck / Q000000981:diagnostic imaging* / Q000196:embryology; D011247:Pregnancy; D011256:Pregnancy Outcome; D012039:Regional Blood Flow; D014430:Twins, Monozygotic; D016216:Ultrasonography, Prenatal