title: Comparison of transvaginal ultrasound, hysteroscopy, and dilatation and curettage in the diagnosis of abnormal vaginal bleeding and intrauterine pathology in perimenopausal and postmenopausal women.
abstract: OBJECTIVE
  To compare transvaginal ultrasound, hysteroscopy, and dilation and curettage (D&C) in the evaluation of women with perimenopausal and postmenopausal bleeding.
  
  
  METHODS
  Descriptive study (Canadian Task Force classification II-1).
  
  
  METHODS
  Seven outpatient clinics.
  
  
  METHODS
  One thousand two hundred eighty-six women.
  
  
  METHODS
  Transvaginal ultrasound, hysteroscopy, and D&C.
  
  
  RESULTS
  Of our patient population, 29 (2.26%) had a histologic diagnosis of endometrial carcinoma; in 2 of them (7.14%) endometrial thickness was 5 mm or less. In 10 women (34.5%), endometrial carcinoma was missed by hysteroscopy (sensitivity 65.52%, specificity 99.92%). Complication rate of D&C was 1.4%.
  
  
  CONCLUSIONS
  In women with perimenopausal and postmenopausal bleeding neither transvaginal ultrasound nor hysteroscopy as a single diagnostic tool is suitable to rule out endometrial cancer.
authors.affiliation: Gynaekologische Praxisklinik, Helene-Weber-Allee 19, Munich 80637, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Deckardt
authors.forename: R P
authors.initials: RP
authors.lastname: Lueken
authors.forename: A
authors.initials: A
authors.lastname: Gallinat
authors.forename: C P
authors.initials: CP
authors.lastname: Möller
authors.forename: D
authors.initials: D
authors.lastname: Busche
authors.forename: W
authors.initials: W
authors.lastname: Nugent
authors.forename: A
authors.initials: A
authors.lastname: Salfelder
authors.forename: H
authors.initials: H
authors.lastname: Dohnke
authors.forename: U
authors.initials: U
authors.lastname: Hoffmeister
authors.forename: E
authors.initials: E
authors.lastname: Dewitt
authors.forename: J
authors.initials: J
authors.lastname: Hennefründ
authors.forename: T
authors.initials: T
authors.lastname: Hasskamp
authors.forename: M
authors.initials: M
authors.lastname: Krichbaum
authors.forename: A
authors.initials: A
authors.lastname: Maucher
authors.forename: U
authors.initials: U
authors.lastname: Auweiler
authors.forename: J
authors.initials: J
authors.lastname: Brökelmann
authors.forename: M
authors.initials: M
authors.lastname: Saks
authors.forename: T
authors.initials: T
authors.lastname: Füger
mesh_terms: D004107:Dilatation and Curettage; D016889:Endometrial Neoplasms / Q000175:diagnosis; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D008875:Middle Aged; D011127:Polyps / Q000175:diagnosis; D014463:Ultrasonography; D014591:Uterine Diseases / Q000175:diagnosis*; D014592:Uterine Hemorrhage / Q000175:diagnosis*; D014621:Vagina / Q000000981:diagnostic imaging*