title: [Neurogenetics in Parkinson's disease].
abstract: The pathogenesis of Parkinson's disease, a progressive degenerative disorder of the central nervous system, remains obscure. 20% of cases are familial. The disorder may be due to a combination of genetic and environmental factors. Some monogenic forms of Parkinson's disease have been described. Many genetic studies explore whether a candidate gene may confer an increased risk for this disease. The search for a genetic susceptibility may lead to establish a preventive therapy.
authors.affiliation: Facultatea de Medicină, Clinica I Neurologie, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
authors.forename: F
authors.initials: F
authors.lastname: Stefanache
authors.forename: D
authors.initials: D
authors.lastname: Hodorog
authors.forename: D
authors.initials: D
authors.lastname: Cuciureanu
mesh_terms: D020022:Genetic Predisposition to Disease; D006801:Humans; D009419:Nerve Tissue Proteins / Q000235:genetics*; D010300:Parkinson Disease / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype; D012307:Risk Factors; D051843:Synucleins
chemical_list: D009419:Nerve Tissue Proteins; D051843:Synucleins