title: On differences between immunity and immunological memory.
abstract: The evolutionary benefits of immunological memory are important: whereas antibodies can be transmitted to offspring by their mother and thereby benefit the species, T cell memory may function to help the individual combat persistent infection in peripheral tissues. Although experimental immunological memory is largely maintained antigen-independently, protective immunity is antigen-dependent.
authors.affiliation: Institute for Experimental Immunology, University Hospital, Zurich, Switzerland. rolf.zinkernagel@pty.usz.ch
authors.forename: Rolf M
authors.initials: RM
authors.lastname: Zinkernagel
mesh_terms: D000818:Animals; D000917:Antibody Formation; D000941:Antigens / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D002417:Cattle; D006801:Humans; D007111:Immunity, Cellular; D007112:Immunity, Maternally-Acquired; D007156:Immunologic Memory; D007159:Immunologic Tests; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology; D009626:Terminology as Topic; D014777:Virus Diseases / Q000276:immunology
chemical_list: D000941:Antigens