[Ghost cell detection in vitreous cytology: clinico-pathological correlation].
OBJECTIVE
To determine the prevalence of detection of ghost cells (GCs) in vitreous hemorrhages (VHs) and correlate it with the development of ghost cell glaucoma. To compare our results with those previously reported.


METHODS
Retrospective analysis of clinical records and vitreous cytology reports (cytospin and direct paraffin embedding) from patients undergoing vitrectomy for VH at Instituto Universitario de Oftalmobiología Aplicada and University Hospital, Valladolid, for the last 2 years.


RESULTS
76 VHs have been analysed; 45 corresponded to proliferative diabetic retinopathy and the remainder to several pathologies. GCs have been detected in 18 cases (25%) (4 out of 76 specimens were excluded): 14 were phakic and 4 pseudophakic. Most of 76 VHs lasted more than 2 months. No case of ghost cell glaucoma was detected, neither previously nor after vitrectomy.


CONCLUSIONS
The frequency of detection of GCs in vitreous cytology may vary according to the cytologic technique. In contrast with the information previously reported, ghost cell glaucoma is an unfrequent disease, particularly after vitrectomy, probably because of a better removal of hemorrhagic debris from the vitreous cavity nowadays. Nevertheless, this diagnosis should not be overlooked.
Baílez
C
C
IOBA, Universidad de Valladolid, Valladolid, España. cbailez@ioba.med.uva.es
Pastor
J C
JC
Martín
F
F
Saornil
M A
MA
D001082:Aqueous Humor / Q000166:cytology*; D002498:Centrifugation; D003930:Diabetic Retinopathy / Q000150:complications / Q000473:pathology; D004910:Erythrocyte Membrane; D015812:Glaucoma, Angle-Closure / Q000209:etiology* / Q000473:pathology; D006801:Humans; D016612:Paraffin Embedding; D012189:Retrospective Studies; D013048:Specimen Handling / Q000379:methods*; D014821:Vitrectomy; D014822:Vitreous Body / Q000473:pathology*; D014823:Vitreous Hemorrhage / Q000150:complications / Q000473:pathology* / Q000601:surgery