Antimicrobial screening of Mentha piperita essential oils.
Essential oils of peppermint Mentha piperita L. (Lamiaceae), which are used in flavors, fragrances, and pharmaceuticals, were investigated for their antimicrobial properties against 21 human and plant pathogenic microorganisms. The bioactivity of the oils menthol and menthone was compared using the combination of in vitro techniques such as microdilution, agar diffusion, and bioautography. It was shown that all of the peppermint oils screened strongly inhibited plant pathogenic microorganisms, whereas human pathogens were only moderately inhibited. Chemical compositions of the oils were analyzed by GC and GC/MS. Using the bioautography assay, menthol was found to be responsible for the antimicrobial activity of these oils.
Işcan
Gökalp
G
Medicinal and Aromatic Plant and Drug Research Centre (TBAM), Anadolu University, 26470-Eskişehir, Turkey.
Kirimer
Neşe
N
Kürkcüoğlu
Mine
M
Başer
K Hüsnü Can
KH
Demirci
Fatih
F
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000032:analysis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D027541:Mentha / Q000737:chemistry*; D008610:Menthol / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D010935:Plant Diseases; D013729:Terpenes / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D009822:Oils, Volatile; D013729:Terpenes; D008610:Menthol; C019466:menthone