title: The role of ascorbic acid role in the differentiation of sclerotia in Sclerotinia minor.
abstract: Sclerotinia minor in culture produces ascorbic acid in levels dependent on oxidative growth conditions and stage of development. During differentiation reduced/oxidized ascorbate ratio decreased by 12 and 6 fold at high and low oxidative stress, respectively. Exogenous ascorbate caused a concentration-dependent decrease of oxidative stress (lipid peroxidation), inhibition of sclerotial differentiation (up to 100%) and delay of differentiatlon (up to 10 days). Ascorbic acid may be produced to help the fungus reduce oxidative stress during growth. The data of this study support our theory proposing that oxidative stress is the inducing factor of sclerotial differentiation in fungi.
authors.affiliation: Department of Biology, University of Patras, Patra, Greece. c.georgiou@upatras.gr
authors.forename: Christos D
authors.initials: CD
authors.lastname: Georgiou
authors.forename: Katherine P
authors.initials: KP
authors.lastname: Petropoulou
mesh_terms: D000975:Antioxidants / Q000378:metabolism* / Q000494:pharmacology; D001203:Ascomycota / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism; D001205:Ascorbic Acid / Q000378:metabolism* / Q000494:pharmacology; D015227:Lipid Peroxidation / Q000187:drug effects; D008054:Lipid Peroxides / Q000378:metabolism; D018384:Oxidative Stress
chemical_list: D000975:Antioxidants; D008054:Lipid Peroxides; D001205:Ascorbic Acid