title: Suppressed cytotoxic T lymphocyte responses in experimental cysticercosis.
abstract: Mitogen-induced T cell responses are suppressed in mice infected with larvae of Taenia crassiceps. The effects of experimental infection on specific T cell responses, however, have not been examined. In the present study, we demonstrate that larval-infected mice exhibit suppressed ability to develop anti-virus specific cytotoxic T lymphocyte (CTL) responses while maintaining apparently normal natural killer (NK) cell responsiveness.
authors.affiliation: Laboratory of Molecular Immunology, NHLBI/NIH, Bethesda, MD 20892, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Spolski
authors.forename: M A
authors.initials: MA
authors.lastname: Alexander-Miller
authors.forename: R E
authors.initials: RE
authors.lastname: Kuhn
mesh_terms: D000818:Animals; D002860:Chromium Radioisotopes / Q000276:immunology; D003551:Cysticercosis / Q000276:immunology*; D005260:Female; D007694:Killer Cells, Natural / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D013621:Taenia / Q000276:immunology*; D014616:Vaccinia virus / Q000276:immunology
chemical_list: D002860:Chromium Radioisotopes