title: Convolutindole A and convolutamine H, new nematocidal brominated alkaloids from the marine bryozoan Amathia convoluta.
abstract: Nematocidal activity of an extract of the marine bryozoan Amathia convoluta, collected from Tasmania's east coast, was ascribed to two novel tribrominated alkaloids: convolutamine H (2) and convolutindole A (5), an indole possessing the unusual N-methoxy moiety. The structures were established by spectroscopic techniques.
authors.affiliation: School of Chemistry, University of Tasmania, PO Box 252-75, Hobart 7001, Tasmania, Australia.
authors.forename: Christian K
authors.initials: CK
authors.lastname: Narkowicz
authors.forename: Adrian J
authors.initials: AJ
authors.lastname: Blackman
authors.forename: Ernest
authors.initials: E
authors.lastname: Lacey
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: Gill
authors.forename: Kirstin
authors.initials: K
authors.lastname: Heiland
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000969:Antinematodal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D002013:Bryozoa / Q000737:chemistry*; D002853:Chromatography, Liquid; D006189:Haemonchus / Q000187:drug effects; D006842:Hydrocarbons, Brominated / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007978:Levamisole / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013648:Tasmania
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000969:Antinematodal Agents; D006842:Hydrocarbons, Brominated; D026121:Indole Alkaloids; C464996:convolutamine H; C464995:convolutindole A; D007978:Levamisole