[The assessment of influence of the diet in the early life, with regard to the effect of protein hydrolysates, on bone mineralization in preterm infants].
The aim of the study was to evaluate the influence of the neonatal diet on bone mineralization. We studied 21 neonates (M-10, F-11) in gestational age 27-35 weeks with body birth weight ranging from 860 to 1800 g (mean 1343 g). 12 children received breast milk with fortifier (BMF--group 1) and 9 children were fed with hydrolysate formulas (group 2). The feeding was modified after child body weight reached 3500 g. The bone mineral density measured by densitometry (DPX) technique and body weight gain were evaluated.


RESULTS
Mean TBBMD (total body bone mass density--g/cm2) at week 40 of postconceptual age in group 1 was 0.450 +/- 0.021 and in group 2 0.457 +/- 0.049. At 3rd month TBBMD was respectively 0.496 +/- 0.034 and 0.478 +/- 0.016, and at 6 month of corrected age 0.546 +/- 0.055 and 0.564 +/- 0.021. The differences were not statistically significant. There were no differences in body weight gain between both groups. At month 7-9 of corrected age body weight were 8650 g and 8475 g respectively.


CONCLUSIONS
We did not demonstrate the differences in TBBMD and body weight gain between children fed with breast milk and BMF or hydrolysate formulas in the first months of life. The low number of children does not allow to generalize this conclusion.
Woynarowska
Martyna
M
Klinika Patologiii i Intensywnej Terapii Noworodka Instytut Matki i Dziecka 02-211 Warszawa, Kasprzaka 17a. kpn@imid.med.pl
Helwich
Ewa
E
Rudzińska-Chazan
Maria
M
Tuieka
Anna
A
Matusik
Hanna
H
D002113:Calcification, Physiologic / Q000187:drug effects*; D002657:Child Development / Q000502:physiology; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D011492:Protein Hydrolysates / Q000494:pharmacology*; D013997:Time Factors
D011492:Protein Hydrolysates