title: B vitamins, vitamin C and hematological measurements in overweight and obese Thais in Bangkok.
abstract: The dynamic changes of socio-economics leading to the industrialisation of countries are known to affect lifestyle and nutritional behaviours of the population. Review of the literature on the prevalence of obesity showed increasing numbers of the overweight and obese during the past decade. However, information on health and nutritional status of the obese in Thailand has not been widely publicized. This study reveals the vitamin status and hematological picture in 270 overweight and obese Thais in Bangkok, Thailand, compared with 175 normal subjects. No statistically significant differences in haemoglobin and hematocrit were observed in the overweight compared with the control subjects. The prevalence of anaemia was 9.8 per cent among male and 17.2 per cent among female overweight and obese subjects compared with 2.6 per cent and 21.2 per cent in male and female normal controls using the cut-off point of haemoglobin concentration as an indicator of anaemia. Prevalence of hypertension was exhibited in both male and female overweight and obese subjects. Even if there were no statistically significant differences in vitamin B1, B2 and B6 in overweight and obese subjects compared with the controls, high percentages of vitamin C and vitamin B2 deficiencies were observed. Vitamin B2 deficiency was detected in 19.7 per cent of overweight and obese males as well as in 28.7 per cent of overweight and obese females using glutathione reductase activity coefficient (alpha EGR) < 1.5 as the cut-off point. However, clinical signs of vitamin B2 deficiencies were rare. There was also a high percentage of vitamin C (antioxidant vitamin) deficiency in 51.5 per cent of the overweight and obese subjects and 41.7 per cent of the controls, respectively. The results suggest more attention should be paid to health study and nutritional problems for the overweight and obese population, especially concerning vitamins and oxidative stress. Further research is still needed in these aspects.
authors.affiliation: Department of Tropical Nutrition and Food Science, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
authors.forename: Talabporn
authors.initials: T
authors.lastname: Harnroongroj
authors.forename: Pornrutsami
authors.initials: P
authors.lastname: Jintaridhi
authors.forename: Niyomsri
authors.initials: N
authors.lastname: Vudhivai
authors.forename: Praneet
authors.initials: P
authors.lastname: Pongpaew
authors.forename: Rungsunn
authors.initials: R
authors.lastname: Tungtrongchitr
authors.forename: Benjaluck
authors.initials: B
authors.lastname: Phonrat
authors.forename: Supranee
authors.initials: S
authors.lastname: Changbumrung
authors.forename: Frank Peter
authors.initials: FP
authors.lastname: Schelp
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia / Q000175:diagnosis / Q000453:epidemiology*; D000886:Anthropometry; D001206:Ascorbic Acid Deficiency / Q000175:diagnosis / Q000453:epidemiology*; D015992:Body Mass Index; D016022:Case-Control Studies; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000378:metabolism; D009767:Obesity, Morbid / Q000453:epidemiology / Q000378:metabolism; D015995:Prevalence; D012307:Risk Factors; D012959:Socioeconomic Factors; D013785:Thailand / Q000453:epidemiology; D014505:Urban Population; D014804:Vitamin B Deficiency / Q000175:diagnosis / Q000453:epidemiology*