title: [Spontaneous rupture of hepatic focal nodular hyperplasia--a rare cause of acute intraabdominal bleedingf].
abstract: Benign hepatic mass lesions are rare. Haemangioma, focal nodular hyperplasia and hepatocellular adenoma represent the most common ones. For the reason of serious clinical complications and potential malignant transformation of hepatic adenoma, surgical resection is the therapy of choice. Unlike adenoma focal nodular hyperplasia is mostly asymptomatic and rarely causes severe complications. We report on a spontaneous rupture and life-threatening intraperitoneal haemorrhage of a large, asymptomatic FNH, where surgical resection was indicated. Within three month after hepatic resection and after termination of oral contraceptives almost complete regeneration of liver tissue and dramatic regression of a second FNH lesion was apparent. Although haemorrhage of hepatic FNH is extremely rare, this case highlights the small risk of rupture in large lesions.
authors.affiliation: Klinik für Allgemein, Viszeral und Transplantationschirurgie, Charité, Campus Virchow Klinikum, Humboldt Universität zu Berlin, Germany. axel.kleespies@aol.com
authors.forename: A
authors.initials: A
authors.lastname: Kleespies
authors.forename: U
authors.initials: U
authors.lastname: Settmacher
authors.forename: P
authors.initials: P
authors.lastname: Neuhaus
mesh_terms: D000328:Adult; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006465:Hemoperitoneum / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000473:pathology; D008115:Liver Regeneration / Q000502:physiology; D012422:Rupture, Spontaneous / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed