title: Multiple HPV-positive basal cell carcinomas on the abdomen in a young pregnant woman.
abstract: Basal cell carcinoma (BCC) is the most common malignant skin tumour. In the last few years, the incidence of multiple BCC has also increased in young patients. We describe the clinical case of a young 29-year-old woman who developed 7 BCC on her abdomen during her first pregnancy and 4 other similar tumours 2 years later during her second pregnancy, all located on the abdomen. Polymerase chain reaction revealed the presence of numerous human papillomavirus DNA sequences. To our knowledge, such a clinical presentation has not been previously reported. Different physiopathological considerations are discussed.
authors.affiliation: Dermatologie, CHU Saint-Pierre, ULB Bruxelles, Belgique. ursula_sass@stpierre-bru.be
authors.forename: U
authors.initials: U
authors.lastname: Sass
authors.forename: A
authors.initials: A
authors.lastname: Theunis
authors.forename: J C
authors.initials: JC
authors.lastname: Noël
authors.forename: J
authors.initials: J
authors.lastname: André
authors.forename: M
authors.initials: M
authors.lastname: Song
mesh_terms: D002280:Basal Cell Carcinoma / Q000473:pathology / Q000821:virology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000032:analysis; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000473:pathology; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000821:virology*; D012878:Skin Neoplasms / Q000473:pathology / Q000821:virology*; D014412:Tumor Virus Infections / Q000473:pathology
chemical_list: D019394:Ki-67 Antigen