Effect of an acrylic intraocular lens with a sharp posterior optic edge on posterior capsule opacification.
OBJECTIVE
To compare the posterior capsule opacification (PCO) inhibiting effect of the sharp posterior optic edge design of the Sensar OptiEdge AR40e intraocular lens (IOL) (Allergan Surgical) with that of the round-edged design of the Sensar AR40 IOL. Setting Department of Ophthalmology, University of Vienna, Vienna, Austria.


METHODS
This prospective randomized patient- and examiner-masked study comprised 106 eyes of 53 patients with bilateral age-related cataract. Each patient had cataract surgery in both eyes and received an AR40 IOL in 1 eye and an AR40e IOL in the other eye. Postoperative examinations were at 1 week, 2 and 6 months, and 1 year. Digital slitlamp and digital retroillumination images of each eye were taken. The amount of PCO was assessed subjectively at the slitlamp and objectively using automated image-analysis software.


RESULTS
The AR40e group had significantly less regeneratory and fibrotic PCO 1 year after surgery. The mean automated image-analysis software PCO score (scale 0 to 10) was 2.19 in the AR40 group and 1.10 in the AR40e group (P <.001). The AR40e group had less peripheral fibrotic PCO. There was no significant difference in patient-reported edge glare between the 2 IOL groups.


CONCLUSIONS
The sharp-edged design of the Sensar OptiEdge AR40e IOL led to significantly less PCO than the round-edged AR40 IOL 1 year postoperatively.
Buehl
Wolf
W
Department of Ophthalmology, University of Vienna, Waehriger Guertel 18-20, 1090 Wien, Austria.
Findl
Oliver
O
Menapace
Rupert
R
Rainer
Georg
G
Sacu
Stefan
S
Kiss
Barbara
B
Petternel
Vanessa
V
Georgopoulos
Michael
M
D000180:Acrylic Resins; D000368:Aged; D019923:Capsulorhexis; D002386:Cataract / Q000517:prevention & control*; D004311:Double-Blind Method; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D018918:Phacoemulsification; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D011474:Prosthesis Design; D016896:Treatment Outcome; D014792:Visual Acuity
D000180:Acrylic Resins