title: Pushing the envelope: chromatin boundaries at the nuclear pore.
abstract: In a novel genetic screen, the nuclear-cytoplasmic transport system was found to reposition DNA to the nuclear pore and establish a barrier to the spread of heterochromatin. These data provide a mechanism for movement and attachment of DNA to a functional nuclear compartment.
authors.affiliation: Department of Pathology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Shinkura
authors.forename: William C
authors.initials: WC
authors.lastname: Forrester
mesh_terms: D021581:Active Transport, Cell Nucleus / Q000502:physiology*; D002262:Carboxy-Lyases / Q000235:genetics / Q000378:metabolism; D004271:DNA, Fungal / Q000235:genetics / Q000378:metabolism*; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D005800:Genes, Fungal / Q000235:genetics; D006570:Heterochromatin / Q000235:genetics / Q000378:metabolism*; D022022:Nuclear Pore / Q000378:metabolism*
chemical_list: D004271:DNA, Fungal; D005656:Fungal Proteins; D006570:Heterochromatin; D002262:Carboxy-Lyases; C022378:phosphoribosylaminoimidazole carboxylase