title: [Pseudomonas aeruginosa corneal abscess refractory to fluoroquinolones].
abstract: OBJECTIVE
  To report a clinical case of a 21-year old male with a severe corneal abscess due to Pseudomonas aeruginosa refractory to intensive treatment with topical Ciprofloxacin.
  
  
  CONCLUSIONS
  A corneal scrapping performed after a wash-out period showed Pseudomonas aeruginosa specimens, which were not sensitive to any of the fluoroquinolones tested. A fortified topical treatment with Ceftazidime healed the corneal abscess. Nowadays, the possibility of resistance to fluoroquinolones should be kept in mind, and we recommend treatment guided by the results of a microbiological study in severe and sight-threatening cases.
authors.affiliation: Hospital General de Móstoles, Madrid, España. ddiazval@nacom.es
authors.forename: D
authors.initials: D
authors.lastname: Díaz Valle
authors.forename: J I
authors.initials: JI
authors.lastname: Alós Cortés
authors.forename: A
authors.initials: A
authors.lastname: Arteaga Sánchez
authors.forename: N
authors.initials: N
authors.lastname: Toledano Fernández
authors.forename: Y
authors.initials: Y
authors.lastname: Poza Morales
authors.forename: T
authors.initials: T
authors.lastname: Díaz-Valle
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000382:microbiology*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002442:Ceftazidime / Q000494:pharmacology / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000494:pharmacology* / Q000627:therapeutic use; D003263:Contact Lenses, Hydrophilic; D003320:Corneal Ulcer / Q000188:drug therapy / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D002442:Ceftazidime