title: Success of intrauterine insemination in women aged 40-42 years.
abstract: OBJECTIVE
  To determine how advancing female age decreases successful outcomes of intrauterine insemination (IUI) alone or combined with ovarian stimulation.
  
  
  METHODS
  Retrospective review.
  
  
  METHODS
  Academic fertility center.
  
  
  METHODS
  Infertile men and women.
  
  
  METHODS
  Intrauterine insemination alone or combined with ovarian stimulation.
  
  
  METHODS
  Pregnancy rates, miscarriage rates, and live birth rates per insemination cycle according to female age.
  
  
  RESULTS
  The 1,117 cycles of IUI resulted in 217 pregnancies, for an overall pregnancy rate for all female ages of 19.4% and a live birth rate of 12.9% per cycle inseminated. The overall live birth rate per insemination declined with advancing maternal age.
  
  
  CONCLUSIONS
  Advancing female age decreases successful outcomes with IUI. The live birth rate with IUI for women 40-42 years old (n = 82) was 9.8% per insemination and may demonstrate that IUI is an appropriate treatment for this age group of women.
authors.affiliation: Fertility Centre, Civic Hospital-Parkdale Clinic, The University of Ottawa, Ontario, Ottawa, Canada. jjhaebe@ottawahospital.on.ca
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Haebe
authors.forename: James
authors.initials: J
authors.lastname: Martin
authors.forename: Francis
authors.initials: F
authors.lastname: Tekepety
authors.forename: Ian
authors.initials: I
authors.lastname: Tummon
authors.forename: Karen
authors.initials: K
authors.lastname: Shepherd
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology; D000328:Adult; D000367:Age Factors; D000375:Aging / Q000502:physiology; D001723:Birth Rate; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D015994:Incidence; D007317:Insemination, Artificial, Homologous; D008297:Male; D008597:Menstrual Cycle / Q000097:blood; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D013076:Sperm Count; D013081:Sperm Motility; D016896:Treatment Outcome
chemical_list: D005640:Follicle Stimulating Hormone