Convolutindole A and convolutamine H, new nematocidal brominated alkaloids from the marine bryozoan Amathia convoluta.
Nematocidal activity of an extract of the marine bryozoan Amathia convoluta, collected from Tasmania's east coast, was ascribed to two novel tribrominated alkaloids: convolutamine H (2) and convolutindole A (5), an indole possessing the unusual N-methoxy moiety. The structures were established by spectroscopic techniques.
Narkowicz
Christian K
CK
School of Chemistry, University of Tasmania, PO Box 252-75, Hobart 7001, Tasmania, Australia.
Blackman
Adrian J
AJ
Lacey
Ernest
E
Gill
Jennifer H
JH
Heiland
Kirstin
K
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000969:Antinematodal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D002013:Bryozoa / Q000737:chemistry*; D002853:Chromatography, Liquid; D006189:Haemonchus / Q000187:drug effects; D006842:Hydrocarbons, Brominated / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007978:Levamisole / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013648:Tasmania
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000969:Antinematodal Agents; D006842:Hydrocarbons, Brominated; D026121:Indole Alkaloids; C464996:convolutamine H; C464995:convolutindole A; D007978:Levamisole