title: [Can urinary corpuscular volume using automated hematology contribute the diagnostic etiology of hematuric microscopy?].
abstract: OBJECTIVE
  To assess the value of measuring urinary corpuscular volume (UCV) with a haematology automat for determination of the glomerular or non-glomerular origin of isolated microscopic haematuria (MHi).
  
  
  METHODS
  Forty-five fresh urine samples taken from 45 consecutive patients, with a median age of 59 years, consultant for MHi on urinary dip-sticks were studied with a haematology automat. After each analysis, MHi was classified into one of the following three groups: High MHi (glomerular, UCV < 50 fl), low MHi (non-glomerular, UCV > 50 fl), MHi of unknown origin (mixed UCV). A complete aetiological assessment of MHi was performed in each case.
  
  
  RESULTS
  The aetiological diagnosis of MHi was established in 28 cases (62%), with a glomerular origin in 16 cases and a non-glomerular origin in 12 cases. UCV was of the glomerular (19 cases), non-glomerular (3 cases) or mixed type (6 cases). When UCV indicated a glomerular or non-glomerular origin for MHi (22/28 = 78.6%), the result was exact in 77% of cases (17/22). The sensitivity to diagnose glomerular haematuria was 100%, the specificity was 37.5%, the PPV was 73.7% and the NPV waas 100%.
  
  
  CONCLUSIONS
  The study of UCV can suggest the origin of MHi, but cannot confirm this origin due to its poor specificity.
authors.affiliation: Service d'Urologie et d'Andrologie, CHU Rangueil, 31403 Toulouse, France. xaviergame@hotmail.com
authors.forename: Xavier
authors.initials: X
authors.lastname: Gamé
authors.forename: Michel
authors.initials: M
authors.lastname: Soulié
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Fontanilles
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Benoit
authors.forename: Joël-Xavier
authors.initials: JX
authors.lastname: Corberand
authors.forename: Pierre
authors.initials: P
authors.lastname: Plante
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001331:Automation; D003928:Diabetic Nephropathies / Q000175:diagnosis; D004909:Erythrocyte Indices; D005260:Female; D006405:Hematology / Q000379:methods; D006417:Hematuria / Q000175:diagnosis* / Q000209:etiology / Q000652:urine; D006801:Humans; D007674:Kidney Diseases / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis; D011934:Reagent Strips; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis
chemical_list: D011934:Reagent Strips