[Periodontal regeneration with enamel derivate proteins (Emdogain)--clinical evaluation].
The study was undertaken in order to evaluate the effect of Emdogain as an adjuvant in periodontal surgery in promoting bone level gain, compared to bone levels after surgery.


METHODS
The study was realised on 6 patients. who had pair test sites and control sites. Two interproximal sites were selected in each patient at a distance from each other, in the same maxilla, with infra-osseous defects with depth > or = 4 mm and width > or = 2 mm. The patients were followed on a long term period, initially and after 8 and 16 months.


RESULTS
The average values of the clinical attachment level were evaluated both in the test sites and in the control group at 8 months and 16 months, The radiographic osseous level continued to recede at the group treated with Emdogain, and in the control group it remained at its initial level. The radiographic gain was ascertained after 16 months.


CONCLUSIONS
This study proves that the topic use of Emdogain as an adjuvant, during periodontal defects surgery, on radicular surfaces, determines a gain in the clinical attachment and an osseous gain observed on X-rays.
Mârţu
S
S
Départament de Parodontologie, Départament de Prothétique Dentàire, Université de Médecine et Pharmacie Gr. T. Popa Iaşi.
Burlui
V
V
Mocanu
C
C
Forna
N
N
D000278:Administration, Buccal; D017024:Chemotherapy, Adjuvant; D003746:Dental Enamel Proteins / Q000008:administration & dosage / Q000627:therapeutic use*; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000188:drug therapy* / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D010510:Periodontal Diseases / Q000188:drug therapy; D016896:Treatment Outcome
D003746:Dental Enamel Proteins; C109069:enamel matrix proteins