title: Surgical management of pancreatic cancer.
abstract: Pancreatic cancer is the fifth leading cause of cancer death in the United States, with an overall survival rate of 3%. Unfortunately, only a minority of patients present with localized disease amenable to surgical resection. Over the past 20 years, improvements in operative and perioperative management have led to a decrease in operative mortality, shorter hospital stay, and overall 5-year survival of approximately 20% in patients undergoing pancreaticoduodenectomy. Despite advances in nonoperative palliation, surgery continues to play an important role in the management of patients with locally advanced, unresectable pancreatic cancer.
authors.affiliation: Department of Surgery, University of Rochester, New York, USA.
authors.forename: Steven A
authors.initials: SA
authors.lastname: Ahrendt
authors.forename: Henry A
authors.initials: HA
authors.lastname: Pitt
mesh_terms: D006801:Humans; D010180:Pancreatectomy / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000601:surgery*; D019990:Perioperative Care; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis; D016896:Treatment Outcome