title: [Prevalence of hypothyroidism and hyperthyroidism in Nord-Trondelag].
abstract: BACKGROUND
  The objective of this survey was to examine the prevalence of thyroid disease including autoimmunity in Norway.
  
  
  METHODS
  All 94,009 inhabitants aged 20 and above in Nord-Trøndelag county, Norway were invited to participate in a health survey.
  
  
  RESULTS
  The prevalence of formerly diagnosed hyperthyroidism was 2.5% in women and 0.6% in men, hypothyroidism 4.8% and 0.9% respectively, increasing with age. In individuals without a history of thyroid disease the median, 2.5 and 97.5 percentiles for TSH (mU/l) were 1.8 and 0.49-5.7 for women and 1.5 and 0.56-4.6 for men. When excluding individuals with positive thyroid peroxidase antibodies (TPOAb), the 97.5 percentiles were 3.6 mU/l for women and 3.4 mU/l for men. The prevalence of pathological TSH values in women and men were TSH > or = 10 mu/l 0.9% and 0.4%; TSH 4.1-9.9 mU/l 5.1% and 3.7%; TSH < or = 0.05 mU/l 0.5% and 0.2%. The prevalence of positive TPOAb was 13.9% in women and 2.8% in men, the lowest percentage was seen with TSH 0.2-2.0 mU/l and increased both with higher and lower TSH values and was higher in women except for those with TSH > or = 10 mU/l (85% TPOAb positive).
  
  
  CONCLUSIONS
  In spite of a high prevalence of recognised thyroid disease in the population a considerable number have undiagnosed thyroid dysfunction and positive TPOAb.
authors.affiliation: Hormonlaboratoriet Aker universitetssykehus 0514 Oslo. trine.bjoro@ioks.uio.no
authors.forename: Trine
authors.initials: T
authors.lastname: Bjøro
authors.forename: Jostein
authors.initials: J
authors.lastname: Holmen
authors.forename: Øystein
authors.initials: Ø
authors.lastname: Krüger
authors.forename: Kristian
authors.initials: K
authors.lastname: Midthjell
authors.forename: Kristin
authors.initials: K
authors.lastname: Hunstad
authors.forename: Thomas
authors.initials: T
authors.lastname: Schreiner
authors.forename: Liv
authors.initials: L
authors.lastname: Sandnes
authors.forename: Henrik
authors.initials: H
authors.lastname: Brochmann
mesh_terms: D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D005260:Female; D006042:Goiter / Q000097:blood / Q000453:epidemiology; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000453:epidemiology*; D007037:Hypothyroidism / Q000097:blood / Q000453:epidemiology*; D007453:Iodide Peroxidase / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D015995:Prevalence; D011795:Surveys and Questionnaires; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood
chemical_list: D000906:Antibodies; D013972:Thyrotropin; D007453:Iodide Peroxidase