title: Nonrobertsonian translocation t(6;11) is associated with infertility in an oligoazoospermic male.
abstract: OBJECTIVE
  To analyze an unusual nonrobertsonian translocation t(6;11) found in an infertile, oligoazoospermic, but otherwise apparently healthy man.
  
  
  METHODS
  Case report with review of the scientific literature.
  
  
  METHODS
  Academic research environment.
  
  
  METHODS
  Infertile, oligoazoospermic, but otherwise apparently healthy man.
  
  
  METHODS
  Peripheral blood lymphocytes were obtained for karyotyping, and metaphases were studied by standard GBG, RBG, and CBG banding procedures.
  
  
  METHODS
  Sperm count, morphology, and GBG, RBG, and CBG banding.
  
  
  RESULTS
  A karyogram revealed a nonrobertsonian balanced translocation t(6;11) with breakpoints at 6q15 and 11p15, as shown by R-, G-, and C-banding.
  
  
  CONCLUSIONS
  Physical contact of unpaired autosomal material with sex chromosomes, which leads to spermatogenic arrest, may be one of the factors that accounts for infertility in men with autosomal aberrations.
authors.affiliation: Dipartimento di Medicina Interna e Terapia Medica, Università degli Studi di Messina, Messina, Italy. fpernice@tiscali.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Pernice
authors.forename: Giuseppa
authors.initials: G
authors.lastname: Mazza
authors.forename: Domenico
authors.initials: D
authors.lastname: Puglisi
authors.forename: Maria Giuseppa
authors.initials: MG
authors.lastname: Luppino
authors.forename: Nicola
authors.initials: N
authors.lastname: Frisina
mesh_terms: D000328:Adult; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics*; D002896:Chromosomes, Human, Pair 6 / Q000235:genetics*; D020732:Cytogenetic Analysis; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D009845:Oligospermia / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics*