Role of lung function testing in the management of mechanically ventilated infants.
The mechanical characteristics of the ventilated lung can only be interpreted when the volume of the lung, the elastic properties, and the degree of airway obstruction have been accurately quantified by pulmonary function testing. More gentle ventilation strategies (permissive hypercapnia) are used, and the efficacy of mechanical ventilation can be verified in the intensive care unit. Pulmonary function testing brings new insights, awareness, and applications, but its limitations need to be taken into account when interpreting the acquired data.
Schibler
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Neonatal and Paediatric Intensive Care Unit, Department of Paediatrics, Children's Hospital University of Bern, Bern, 3010 Bern, Switzerland. andreas.schibler@insel.ch
Frey
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D000403:Airway Resistance / Q000502:physiology; D002245:Carbon Dioxide / Q000097:blood; D002908:Chronic Disease; D005652:Functional Residual Capacity / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D008170:Lung Compliance / Q000502:physiology; D008171:Lung Diseases / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D008176:Lung Volume Measurements / Q000379:methods; D010313:Partial Pressure; D011175:Positive-Pressure Respiration / Q000379:methods; D012127:Respiratory Distress Syndrome, Newborn / Q000097:blood / Q000503:physiopathology / Q000628:therapy; D013990:Tidal Volume / Q000502:physiology
D002245:Carbon Dioxide