[The effect of vilon on the thymus and spleen in a radiation model of premature aging].
Low dose ionizing radiation induced accelerated aging of the thymus and the spleen in rat. Treatment with a synthetic dipeptide vilon (Lys-Glu) inhibited partly this process. The data suggest that vilon is a candidate for geriatric research and practice.
Kniaz'kin
I V
IV
St. Petersburg Institute of Bioregulation and Gerontology, North-West Branch, Russian Academy of Medical Science, 3, Dynamo Prospect, 197110, St. Petersburg, Russia.
Poliakova
V O
VO
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D019588:Aging, Premature / Q000209:etiology / Q000503:physiopathology*; D000818:Animals; D004151:Dipeptides / Q000494:pharmacology*; D004195:Disease Models, Animal; D005720:Gamma Rays; D007150:Immunohistochemistry; D008297:Male; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000187:drug effects* / Q000503:physiopathology / Q000528:radiation effects; D013950:Thymus Gland / Q000187:drug effects* / Q000503:physiopathology / Q000528:radiation effects
D000276:Adjuvants, Immunologic; D004151:Dipeptides; C415909:lysylglutamic acid