[Observation on the factors influencing infection rate of Meriones unguiculatus with Brugia malayi].
OBJECTIVE
To explore the factors influencing the infection rate of M. unguiculatus with B. malayi.


METHODS
The survival rate, infection rate and infection intensity were observed in M. unguiculatus infected with the infective larvae of B. malayi contained in normal saline, antibiotic, glucose or culture medium RPMI1640, respectively.


RESULTS
The survival rate, infection rate and rate of infection intensity in normal saline group, antibiotic group, glucose group and RPMI1640 group were 80.9%, 60.5%, and 43.4%; 98.8%, 52.9% and 30.6%; 98.0%, 68.8% and 50.0%; 91.2%, 67.7% and 51.6%, respectively. The rate and the infection intensity were higher in the jirds infected with the 6th generation of Zhejiang strain than that with the 31st generation of Guizhou strain.


CONCLUSIONS
The antibiotic was found to raise the living rate of the infected jirds, but reduce the infection rate and infection degree intensity; whereas glucose and culture medium RPMI1640 could raise the positive rate and the infectino. The jird was more susceptible to the 6th generation of Zhejiang strain than the 31st generation of Guizhou strain of B. malayi.
Xu
D
D
Department of Parasitology, Shanghai Second Medical University, Shanghai 200025.
Wan
Q
Q
Li
J
J
Nie
W
W
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D017178:Brugia malayi / Q000472:pathogenicity*; D005849:Gerbillinae / Q000469:parasitology*; D005947:Glucose / Q000494:pharmacology; D007814:Larva
D000900:Anti-Bacterial Agents; D005947:Glucose