title: Interventions for treating proximal humeral fractures in adults.
abstract: BACKGROUND
  Proximal humeral fractures are common yet management varies widely. In particular, the role and timing of any surgical intervention have not been clearly defined.
  
  
  OBJECTIVE
  To collate and evaluate the scientific evidence supporting the various methods used for treating proximal humeral fractures.
  
  
  METHODS
  We searched the Cochrane Musculoskeletal Injuries Group specialised register, MEDLINE, EMBASE, the Cochrane Controlled Trials Register, CINAHL, the National Research Register (UK), AMED, PEDro and bibliographies of trial reports. The search was completed in November 2001.
  
  
  METHODS
  All randomised studies pertinent to the treatment of proximal humeral fractures were selected.
  
  
  METHODS
  Independent quality assessment and data extraction were performed by two reviewers. Although quantitative data from trials are presented, trial heterogeneity prevented pooling of results.
  
  
  RESULTS
  Ten randomised trials were included. All were small trials; the largest study involved only 85 patients. Bias in these trials could not be ruled out. Six trials evaluated conservative treatment, three compared surgery with conservative treatment and one compared two surgical techniques. In the 'conservative' group there was very limited evidence indicating that the type of bandage used made any difference in terms of time to fracture union and the functional end result. However, an arm sling was generally more comfortable than a body bandage. There was some evidence that mobilisation at one week instead of three weeks alleviated pain in the short term without compromising long term outcome. Two trials provided some evidence that patients, when given sufficient instruction to pursue an adequate physiotherapy programme, could generally achieve a satisfactory outcome if allowed to exercise without supervision. Operative reduction improved fracture alignment in two trials. However, in one trial, surgery was associated with a greater risk of complication, and did not result in improved shoulder function. In one trial, hemi-arthroplasty resulted in better short-term function with less pain and less need for help with activities of daily living when compared with conservative treatment for severe injuries. Fracture fixation of severe injuries was associated with a high rate of re-operation in one trial, comparing tension-band wiring fixation with hemi-arthroplasty.
  
  
  CONCLUSIONS
  Only tentative conclusions can be drawn from the available randomised trials, which do not provide robust evidence for many of the decisions that need to be made in contemporary fracture management. It is unclear whether operative intervention, even for specific fracture types, will produce consistently better long term outcomes. There is a need for good quality evidence for the management of these fractures.
authors.affiliation: Lothian University Hospitals NHS Trust, The New Royal Infirmary of Edinburgh, Little France, Edinburgh, UK, EH16 4SU. j.n.a.gibson@ed.ac.uk
authors.forename: J N
authors.initials: JN
authors.lastname: Gibson
authors.forename: H H
authors.initials: HH
authors.lastname: Handoll
authors.forename: R
authors.initials: R
authors.lastname: Madhok
mesh_terms: D000328:Adult; D001458:Bandages; D005592:Fracture Fixation / Q000379:methods; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012784:Shoulder Fractures / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome