title: Student-designed clinical trials: evaluating self-directed learning in pharmacology.
abstract: An evaluation exercise was developed for a third-year undergraduate problem-based course in pharmacology for science students. They were asked to design a clinical trial to evaluate a novel drug for an existing condition or an established drug for a novel condition. The exercise was assessed on both required elements (provision of a clear rationale, clear definition of outcome measures, patient inclusion/exclusion criteria, statistical analysis and critical assessment of available information) as well as on aesthetic elements (imagination, flair and readability). To promote self-directed learning, students were given minimal instructions and received no formal lectures on the subject of clinical trials. The exercise has been rated very highly by the students.
authors.affiliation: Department of Medicine, McMaster University, HSC-3N5C, 1200 Main Street West, Hamilton, ON L8N 3Z5, Canada. chari@mcmaster.ca
authors.forename: P K
authors.initials: PK
authors.lastname: Rangachari
mesh_terms: D002986:Clinical Trials as Topic; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D010600:Pharmacology / Q000193:education*; D018794:Problem-Based Learning / Q000379:methods*; D012107:Research Design