title: Proteins as active compounds involved in insecticidal activity of mushroom fruitbodies.
abstract: Many mushrooms are toxic to insects. To identify the chemicals involved in insecticidal activity, the toxicity of 14 species has been studied for water solubility, thermolability, and dialysis. The data strongly suggest that proteins are responsible for most of the insecticidal activity of mushroom fruitbodies and may be a source of genes available for plant protection against insects. Among proteins, lectins and hemolysins were good insecticide candidates because the toxicities were not affected by protease.
authors.affiliation: Groupe de Biochimie des Protéines, Université Paul Sabatier, Toulouse, France.
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
authors.forename: Véronique
authors.initials: V
authors.lastname: Triguéros
authors.forename: Laurent
authors.initials: L
authors.lastname: Paquereau
authors.forename: Louis
authors.initials: L
authors.lastname: Chavant
authors.forename: Didier
authors.initials: D
authors.lastname: Fournier
mesh_terms: D000363:Agaricales / Q000378:metabolism*; D000818:Animals; D004331:Drosophila melanogaster / Q000187:drug effects*; D005656:Fungal Proteins / Q000494:pharmacology*; D006361:Heating; D006460:Hemolysin Proteins / Q000378:metabolism; D006801:Humans; D007306:Insecticides / Q000494:pharmacology*; D037102:Lectins / Q000378:metabolism; D010572:Pest Control, Biological / Q000379:methods*; D015843:Serpins / Q000378:metabolism; D014020:Tissue Extracts
chemical_list: D005656:Fungal Proteins; D006460:Hemolysin Proteins; D007306:Insecticides; D037102:Lectins; D015843:Serpins; D014020:Tissue Extracts