title: [The evaluation of the left ventricle function in patients with aortic stenosis and severe heart failure after surgical treatment of valvular heart disease].
abstract: Surgical treatment of aortic stenosis in patients (pts) with severe heart failure represents high-risk procedure. The aim of this study was to identify prognostic factors and assess the late outcome after aortic valve replacement (AVR) in patients with isolated aortic stenosis and left ventricle ejection fraction (EF) < or = 40%. The study group consisted of 37 pts 25 (67%) men and 12 (33%) women, aged 57 +/- 12 yrs. Mean follow-up period was 18 +/- 17 months (range 6 to 72 months). Before AVR and within follow-up period clinical assessment was based on NYHA classes and echocardiographic study to evaluate left ventricle function. Early mortality rate was 8.3%, late mortality was 5.8%. EF significantly improved from 27 +/- 7% to 59 +/- 15% (p < 0.001) after AVR. It was accompanied by clinical improvement. Left ventricle function improvement did not depend on age, sex of patients, concomitant revascularization and preoperative maximum transaortic gradient. Significant correlation (r = -0.4, p = 0.02) between preoperative left ventricle end-diastolic diameter and postoperative EF improvement was noted.
authors.affiliation: Klinika Wad Nabytych Serca Instytutu Kardiologii w Warszawie.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Zakrzewski
authors.forename: Ewa
authors.initials: E
authors.lastname: Orłowska-Baranowska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Hryniewiecki
authors.forename: Michał
authors.initials: M
authors.lastname: Cybulski
authors.forename: Piotr
authors.initials: P
authors.lastname: Hoffman
authors.forename: Irena
authors.initials: I
authors.lastname: Rawczyńska-Englert
mesh_terms: D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery; D005260:Female; D006333:Heart Failure / Q000209:etiology*; D006349:Heart Valve Diseases / Q000150:complications* / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D012720:Severity of Illness Index; D015996:Survival Rate; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000209:etiology