Microcystic adnexal carcinoma (MAC) of the scalp with extensive pilar differentiation.
BACKGROUND
Microcystic adnexal carcinoma (MAC), or sclerosing sweat duct tumor, is an uncommon, locally aggressive tumor. It typically involves the upper lip or face of middle-aged adults and rarely involves the scalp. It is characterized histologically by both pilar and eccrine differentiation and is associated with frequent perineural invasion. MAC is frequently misdiagnosed because of its bland and asymptomatic clinical presentation. In addition, its defining histologic features may be missed with a superficial biopsy.


OBJECTIVE
To describe a case of MAC in the scalp treated with Mohs surgery. We describe a case with extensive pilar differentiation and clear cell changes. In addition, the clinical and histologic characteristics of this rare neoplasm are reviewed.


METHODS
Mohs micrographic surgery (MMS) was performed on this neoplasm.


RESULTS
The tumor was successfully excised in one surgery (five stages) and is without evidence of recurrence at 18 months.


CONCLUSIONS
We present a case of MAC of the scalp in a 64-year-old white man treated successfully with MMS.
Callahan
Elizabeth F
EF
Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
Vidimos
Allison T
AT
Bergfeld
Wilma F
WF
D018280:Carcinoma, Skin Appendage / Q000473:pathology* / Q000601:surgery; D018859:Hair Follicle / Q000473:pathology; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D012535:Scalp; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery