title: [FDG PET scan of metastases in recurrent medullary carcinoma of the thyroid gland].
abstract: Searching for metastases of medullary thyroid cancer (MTC), FDG PET was applied. PET results were compared with those of conventional diagnostic imaging procedures. After primary treatment, 52 MTC patients with elevated serum tumor marker levels and/or general symptoms (diarrhoea/flush) underwent radiological (CT/MRI), 131-iodine labeled metaiodo-benzylguanidine (MIBG) whole-body scintigraphy and FDG PET investigations. At least one pathological lesion was detected in 49 patients by PET, 35 by CT, 32 by MRI and 3 by MIBG. FDG PET was far superior to the other methods in identifying metastases in the supradiaphragmatic lymphatic regions. In the follow-up of MTC patients, FDG PET was more sensitive in localizing tumorous LN involvement, especially in the cervical, supraclavicular and mediastinal lymphatic regions, compared to other imaging modalities.
authors.affiliation: Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, PET Centrum, Debrecen. szakall@pet.dote.hu
authors.forename: Szabolcs
authors.initials: S
authors.lastname: Szakáll
authors.forename: Gábor
authors.initials: G
authors.lastname: Bajzik
authors.forename: Imre
authors.initials: I
authors.lastname: Repa
authors.forename: Tünde
authors.initials: T
authors.lastname: Miklovicz
authors.forename: Gabriella
authors.initials: G
authors.lastname: Dabasi
authors.forename: István
authors.initials: I
authors.lastname: Sinkovics
authors.forename: Olga
authors.initials: O
authors.lastname: Esik
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D018276:Carcinoma, Medullary / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000628:therapy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007457:Iodine Radioisotopes; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D014055:Tomography, Emission-Computed / Q000379:methods; D014057:Tomography, X-Ray Computed
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18