title: (P(C(6)H(5))(3))CpRu(+)-catalyzed deprotection of allyl carboxylic esters.
abstract: A new and efficient catalytic method for deprotection of allyl carboxylic esters using a transition metal complex is reported. The reaction proceeds with a high substrate/catalyst ratio and without use of additional nucleophiles, giving the deprotected carboxylic acid in a quantitative yield. A variety of substrates, including the multifunctional amino acids and peptides, are also usable. The new method is more efficient, safe, and operationally simple in comparison to the conventional palladium-catalyzed method.
authors.affiliation: Department of Chemistry and Research Center for Materials Science, Nagoya University, Chikusa, Nagoya 464-8602, Japan. kitamura@os.rcms.nagoya-u.ac.jp
authors.forename: Masato
authors.initials: M
authors.lastname: Kitamura
authors.forename: Shinji
authors.initials: S
authors.lastname: Tanaka
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshimura