[Morphological impairment of oogenesis in experimental iodine-dependent thyroid transformation].
Histophysiology of white rats' ovaries was studied in iodine-deficient and iodine-enriched diets; in such diets kept in pregnancy or postnatal period. The iodine-deficient diet leads to low histofunctional thyroid activity, formation of cysts in the ovaries, slow folliculogenesis, hypotrophy of yellow body tissue, overgrowth of the connective tissue, thickening of the theca of the cavernous follicles, hardening of the vessels of the cortical and core substances. The fertility fell by 18%. In long-term intake of iodine-rich diet and in pregnancy essential intensification of histofunctional activity of the thyroid gland was noticed and in the ovaries there was a distinct hypertrophy of the yellow bodies, hyperplasia of lutein cells, endomitosis. Postnatal structural changes of the gonads were registered as well as micro- and macrocystic degeneration of yellow body tissue, atretic and cavernous follicles, dystrophic transformation of interstitial tissue.
Rodzaevskaia
E B
EB
Saratov State Medical University, 410701, Saratov.
D000818:Animals; D004032:Diet; D005260:Female; D007455:Iodine / Q000008:administration & dosage / Q000172:deficiency / Q000378:metabolism*; D009865:Oocytes / Q000473:pathology; D009866:Oogenesis; D010053:Ovary / Q000473:pathology* / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D013961:Thyroid Gland / Q000378:metabolism* / Q000473:pathology*
D007455:Iodine