title: [Relationship between the Area Under the Curve of detrussor contraction during micturition and the usual parameters of flow-pressure rate in women].
abstract: OBJECTIVE
  The aim of this work was to assess the relationship between a new urodynamic parameter Area Under Curve of detrusor pressure during voiding (AUCdet) and the usual pressure flow study parameters.
  
  
  METHODS
  103 women with various urinary symptoms (incontinence, dysuria, chronic bladder pain or frequent urinary infection) had a urodynamic evaluation with pressure flow analysis. The intravesical pressure was measured through a 6CH Porges Neoplex and the intra-abdominal pressure through a 6CH rectal catheter in an empty rectum. Pressure-flow study was performed one time in each patient. The maximum flow rate (Qmax), the detrusor pressure at maximal flow (PdetQmax), the vesical pressure at maximal flow (PvesQmax), the urethral resistance defined as the ratio between the PvesQmax and Qmax2 (RU) and the AUCdet/Vol were recovered.
  
  
  RESULTS
  85 women were included and mean age was 55 years old. The averages were 19.42 for Qmax, 28.91 for PdetQmax, 63.85 for PvesQmax, 2.10 for RU and 7.83 for AUCdet/Vol. The correlation with AUCdet/Vol were for Qmax -0.80 p < 0.0001, for PdetQmax 0.71 p < 0.0001, for PvesQmax 0.42 p < 0.001 and for RU 0.84 p < 0.0001.
  
  
  CONCLUSIONS
  AUCdet/Vol is the first urodynamic parameter which takes into account the whole detrusor contraction during voiding. AUCdet/Vol is relatively close to the urethral resistance. The very high degree of correlation between RU and AUCdet/Vol confirms clinically this definition of the RU. Further studies are needed to assess the validity of AUCdet/Vol.
authors.affiliation: Service d'Urologie, Institut Régional de Réadaptation, CHU Nancy-Brabois, Vandoeuvre les Nancy, France. l.cormier@chu-nancy.fr
authors.forename: Luc
authors.initials: L
authors.lastname: Cormier
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Galas
authors.forename: Jérôme
authors.initials: J
authors.lastname: Ferchaud
authors.forename: Philippe
authors.initials: P
authors.lastname: Mangin
mesh_terms: D019540:Area Under Curve; D005260:Female; D006801:Humans; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology*; D009130:Muscle, Smooth / Q000503:physiopathology*; D011312:Pressure; D014521:Urethra / Q000502:physiology / Q000503:physiopathology; D014554:Urination / Q000502:physiology*; D014555:Urination Disorders / Q000503:physiopathology* / Q000652:urine; D014563:Urodynamics / Q000502:physiology*