The Italian gynecological consensus statement on the use of epoetin alfa in the management of anemia.
A Consensus Conference on the use of recombinant human erythropoietin (rHuEPO, epoetin alfa) in gynecologic tumors was held in Rome in March 1999, and an associated consensus paper has been published in Italian. The current paper updates several discussions that took place at the 1999 meeting concerning epoetin alfa treatment in breast, ovarian, and cervical cancers; the role of epoetin alfa in mobilizing progenitor hematopoietic cells; administration of epoetin alfa in combination with granulocyte colony-stimulating factor; and the effect of hemoglobin levels on outcome of radiation or chemoradiation treatment.
Pecorelli
Sergio
S
Department of Gynecologic Oncology, Universita' degli Studi di Brescia, Italy.
D000740:Anemia / Q000188:drug therapy* / Q000209:etiology*; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001803:Blood Transfusion; D001943:Breast Neoplasms / Q000097:blood / Q000150:complications / Q000188:drug therapy; D000068817:Epoetin Alfa; D004921:Erythropoietin / Q000627:therapeutic use*; D005260:Female; D005833:Genital Neoplasms, Female / Q000097:blood / Q000150:complications* / Q000628:therapy*; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006397:Hematinics / Q000627:therapeutic use*; D019650:Hematopoietic Stem Cell Mobilization; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications / Q000188:drug therapy; D011788:Quality of Life; D018714:Radiotherapy, Adjuvant; D011994:Recombinant Proteins; D002583:Uterine Cervical Neoplasms / Q000097:blood / Q000150:complications / Q000188:drug therapy
D000970:Antineoplastic Agents; D006397:Hematinics; D006454:Hemoglobins; D011994:Recombinant Proteins; D004921:Erythropoietin; D016179:Granulocyte Colony-Stimulating Factor; D000068817:Epoetin Alfa