[A mechanism conjugating cellular and individual adaptations could be produced from space biology].
To know a basic mechanism of biological organism on the earth, we can have a standard point to space. An example is hindlimb suspension model that could induce muscle atrophy. This model mimics adaptational changes under zero gravity; in turn the effect of gravity on the biological system developing on the earth. We can understand gravity is a stress from the specific changes of stress protein induced by mechanical stimuli depending on gravity. Recent development of fluorescent microscopy and time-lapse visual system brought us a possibility of analysis to see visualization of dynamic properties of molecular and cellular events in living cells. Especially dynamic fluctuation of cytoskeleton may include new ideas of biological strategy of living organism on the earth and possibly may suggest subtle changes in space.
Atomi
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Y
Department of Life Science, the University of Tokyo, Komaba, Meguro-ku, Tokyo, Japan. atomi@idaten.c.u-tokyo.ac.jp
D000222:Adaptation, Physiological; D000818:Animals; D001690:Biological Science Disciplines; D002468:Cell Physiological Phenomena; D003599:Cytoskeleton / Q000502:physiology; D006112:Gravitation; D006360:Heat-Shock Proteins; D009133:Muscular Atrophy / Q000503:physiopathology; D013026:Space Flight; D013314:Stress, Mechanical; D014893:Weightlessness
D006360:Heat-Shock Proteins