title: An addition to geographic hematology: chronic myeloproliferative diseases are infrequent in Mexican Mestizos.
abstract: BACKGROUND
  The chronic myeloproliferative diseases (CMPDs) include chronic myelogenous leukemia (CML), primary (essential) thrombocythemia (PT), agnogenic myeloid metaplasia (AMM), and polycythemia vera (PV). Certain hematological malignancies have a different prevalence in our country than in countries with Caucasian populations. Data indicate that the prevalence of CML in our country is similar to that found in Caucasians; however, the prevalence of the other CMPDs has not been studied.
  
  
  METHODS
  In a total of 8069 individuals studied between June 1983 and March 2001 in the Centro de Hematologia y Medicina Interna de Puebla, we assessed the prevalence of CML, PT, AMM, and PV. Some of the clinical features of these individuals were also assessed.
  
  
  CONCLUSIONS
  Forty-nine patients with CML, 14 with PT, 7 with AMM, and 3 with PV were identified. The clinical presentations of these CMPDs were not different from those described in Caucasians.
  
  
  CONCLUSIONS
  We found that CML was more than 3 times more frequent than PT, that both PV and AMM were exceptional, and that PT, AMM, and PV were significantly less frequent in Mexican than in Caucasian populations (P < .01).
authors.affiliation: Centro de Hematología y Medicina Interna de Puebla, PUE, México. gruiz1@puebla.megared.net.mx
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Ruiz-Argüelles
authors.forename: Briceida
authors.initials: B
authors.lastname: López-Martínez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Lobato-Mendizábal
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Ruiz-Delgado
mesh_terms: D002908:Chronic Disease; D006801:Humans; D015994:Incidence; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000453:epidemiology; D008800:Mexico / Q000453:epidemiology / Q000208:ethnology; D009196:Myeloproliferative Disorders / Q000453:epidemiology*; D011087:Polycythemia Vera / Q000453:epidemiology; D055728:Primary Myelofibrosis / Q000453:epidemiology; D044469:Racial Groups; D013920:Thrombocythemia, Essential / Q000453:epidemiology; D019371:Topography, Medical