title: Characterization and implications of bioassay variation.
abstract: Statistical models for variance components can be used to characterize the components of variance in potency estimates obtained from a bioassay. We outline these methods and discuss the implications for replication strategy. An example is provided.
authors.affiliation: Genentech, South San Francisco, CA 94080, USA.
authors.forename: M
authors.initials: M
authors.lastname: Ostland
mesh_terms: D001681:Biological Assay / Q000592:standards*; D015233:Models, Statistical; D015203:Reproducibility of Results