title: [CA 15-3 and CEA markers - prognostic factors in breast cancer].
abstract: For the increasing of sensibility and specificity in the monitoring of the diagnosis and treatment of breast cancer it is used the simultaneous determination of two tumoral markers: CA 15-3 and CEA. This study try to demonstrate the grade of involvement in diagnostic and screening. We have determinate CA 15-3 and CEA in 73 serum samples. The correlation between the stage of malignancies and CA 15-3 levels was relieved in the second section of this study. The third section follow up the dynamic evolution of CA 15-3 marker in pre- and postoperator (14 days) stages obtaining a decreasing of CA 15-3 level. The obtained results for CEA does not establish any clinical rules in order to compare with the CA 15-3 level and disease stages. The easy-used and non-invasive determination, the early increasing of it's level and it's preservation recommend glycoprotein CA 15-3 like an current clinical instrument.
authors.affiliation: Clinica a II-a Obstetrică Ginecologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
authors.forename: E
authors.initials: E
authors.lastname: Anton
authors.forename: G
authors.initials: G
authors.lastname: Costăchescu
authors.forename: G
authors.initials: G
authors.lastname: Costăchescu
mesh_terms: D001943:Breast Neoplasms / Q000097:blood* / Q000473:pathology; D002272:Carcinoembryonic Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D018396:Mucin-1 / Q000097:blood*; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D002272:Carcinoembryonic Antigen; D018396:Mucin-1