title: Can changes in systolic longitudinal deformation quantify regional myocardial function after an acute infarction? An ultrasonic strain rate and strain study.
abstract: OBJECTIVE
  The aim of this study was to evaluate the additional value of ultrasonic strain rate and strain to myocardial velocity in the identification and quantification of regional asynergy after an acute myocardial infarction (MI).
  
  
  METHODS
  Forty patients (59 +/- 13 years) were investigated 3 +/- 2 days after a first infarction and compared with 14 age-matched controls with normally contracting segments (group A, n = 146). Longitudinal myocardial velocities, strain rate (SR) and strain (epsilon) were postprocessed from basal, mid, and apical segments interrogated using apical views. In a subset of patients with coronary angiograms (n = 24), myocardial segments were divided into 3 groups: normally contracting segments supplied by a normal coronary artery (group B1), normally contracting segments supplied by a diseased coronary artery (group B2), and segments with abnormal motion (group B3). Velocities were decreased in patients with myocardial infarction (MI) (P <.05 vs controls) but failed to accurately differentiate normally from abnormally contracting segments. At the opposite end, systolic SR and epsilon decreased significantly with segmental asynergy severity and could identify infarct-involved segments (group B3) with a sensitivity/specificity of 85% (systolic SR and epsilon cutoff values of -0.8 s(-1) and -13%, respectively).
  
  
  CONCLUSIONS
  Strain rate and strain can better assess segmental dysfunction severity than myocardial velocities alone after an acute MI.
authors.affiliation: Department of Cardiology, University Hospital Gasthuisberg, Leuven, Belgium. fadi.jamal@univ-lyon1.fr
authors.forename: Fadi
authors.initials: F
authors.lastname: Jamal
authors.forename: Tomasz
authors.initials: T
authors.lastname: Kukulski
authors.forename: George R
authors.initials: GR
authors.lastname: Sutherland
authors.forename: Frank
authors.initials: F
authors.lastname: Weidemann
authors.forename: Jan
authors.initials: J
authors.lastname: D'hooge
authors.forename: Bart
authors.initials: B
authors.lastname: Bijnens
authors.forename: Geneviève
authors.initials: G
authors.lastname: Derumeaux
mesh_terms: D000368:Aged; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D012372:ROC Curve; D012680:Sensitivity and Specificity; D016276:Ventricular Function