[Changes in calcium and magnesium levels of lymphocytes in patients with diabetes and hypertension].
To investigate the cellular basis linking non-insulin-dependent diabetes mellitus(NIDDM) and hypertension, we used the atomic absorption spectrometry to detect Ca2+ and Mg2+ levels of serum and lymphocytes in patients with the above diseases. The results were that serum Ca2+ and Mg2+ levels had no change, but lymphocyte Ca2+ level increased obviously and lymphocyte Mg2+ level decreased obviously in both diseases, compared with normal controls. There were no difference between hypertension and NIDDM with and without hypertension. Ca2+ and Mg2+ levels of lymphocytes in patients with hypertension correlated with the systolic pressure respectively(Ca2+, r = 0.4633, P < 0.05; Mg2+, r = -0.4412, P < 0.05), but their levels in patients with NIDDM were not correlated with the fasting blood glucose. The results suggest that there is an abnormal Ca2+ and Mg2+ metabolism in lymphocytes in patients with hypertension and NIDDM.
Mo
Z
Z
Department of Endocrinology, Third Affiliated Hospital, Hunan Medical University, Changsha 410013.
Zhang
M
M
Guan
Y
Y
Jian
W
W
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002118:Calcium / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D008214:Lymphocytes / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
D008274:Magnesium; D002118:Calcium