title: Hereditary thrombophilias are not associated with a decreased live birth rate in women with recurrent miscarriage.
abstract: OBJECTIVE
  To assesses the live birth rate without treatment in women with hereditary thrombophilia who have recurrent miscarriage and women without thrombophilia who have recurrent miscarriage.
  
  
  METHODS
  Prospective observational study.
  
  
  METHODS
  Tertiary referral unit in university hospital.
  
  
  METHODS
  One hundred twenty women with thrombophilia and 65 women without thrombophilia.
  
  
  METHODS
  Number of live births or repeated miscarriages.
  
  
  RESULTS
  Of the 185 patients, 44 with thrombophilia and 26 without thrombophilia have conceived. Nineteen of the 44 pregnancies (43.2%) in thrombophilia patients have terminated in live births, compared with 8 of 26 pregnancies (30.8%) in patients without thrombophilia. This difference is not statistically significant.
  
  
  CONCLUSIONS
  Hereditary thrombophilia did not seem to affect the live birth rate in women with recurrent miscarriage.
authors.affiliation: Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel. carp@netvision.net.il
authors.forename: Howard
authors.initials: H
authors.lastname: Carp
authors.forename: Mordechai
authors.initials: M
authors.lastname: Dolitzky
authors.forename: Ilan
authors.initials: I
authors.lastname: Tur-Kaspa
authors.forename: Aida
authors.initials: A
authors.lastname: Inbal
mesh_terms: D000026:Abortion, Habitual / Q000150:complications* / Q000503:physiopathology*; D000328:Adult; D001723:Birth Rate; D005260:Female; D006720:Homozygote; D006801:Humans; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000235:genetics; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000503:physiopathology; D011446:Prospective Studies; D019851:Thrombophilia / Q000150:complications* / Q000235:genetics*
chemical_list: D000587:Oxidoreductases Acting on CH-NH Group Donors; D042965:Methylenetetrahydrofolate Reductase (NADPH2)