title: [Correlation of different types of emphysema in high-resolution computed tomography (HR-CT) with the ILO-classification of coal workers pneumoconiosis].
abstract: OBJECTIVE
  The complaints of patients suffering from pneumoconiosis and the decrease in cardio-respiratory function tests are related to the major complications, emphysema or bronchitis, resp. to a lesser degree the complaints are directly influenced by the silicotic process itself. Up to now, no large study has analysed the correlation of different types and severity of emphysema with the ILO-classification of pneumoconiosis in miners.
  
  
  METHODS
  In 104 miners the severity of pneumoconiosis was classified by ILO. By HR-CT the type and severity of emphysema was analysed using a 4-point-scale. The correlation of emphysema with the ILO-classification was tested with Pearson-correlation.
  
  
  RESULTS
  The centrolobular emphysema was the dominant type with 59 %, but there was no dependence on the severity of pneumoconiosis. Only the paracicatricial emphysema had a significant correlation (p < 0.05) with the degree of large opacities. On the other hand, the paracicatricial emphysema was only detected in 32 %; under quantitative aspects it was seen to be less common than the centrolobular, the parapleural and the paraseptal emphysema (46 %). There was no significant correlation with the size and distribution of the small opacities and the different types of emphysema.
  
  
  CONCLUSIONS
  Only the large opacities had a significant correlation with the appearance of paracicatricial emphysema. The other types of emphysema, especially, the dominant centrolobular type had no obvious association with pneumoconiosis. The multifactoral genesis of emphysema has to be taken into account.
authors.affiliation: Institut für Klinische Radiologie, LMU München-Grosshadern, Germany. Roger.Eibel@ikra.med.uni-muenchen.de
authors.forename: R
authors.initials: R
authors.lastname: Eibel
authors.forename: A
authors.initials: A
authors.lastname: Weber
authors.forename: S
authors.initials: S
authors.lastname: Stolpe
authors.forename: U
authors.initials: U
authors.lastname: Hellenbrand
authors.forename: T
authors.initials: T
authors.lastname: Bauer
mesh_terms: D000328:Adult; D000368:Aged; D000874:Anthracosilicosis / Q000145:classification / Q000000981:diagnostic imaging*; D002921:Cicatrix / Q000000981:diagnostic imaging; D003031:Coal; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D008906:Mining; D011656:Pulmonary Emphysema / Q000145:classification / Q000000981:diagnostic imaging*; D012907:Smoking / Q000009:adverse effects; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D003031:Coal