title: Tensile fatigue behaviour of articular cartilage.
abstract: Although fatigue has been implicated in cartilage failure there are only two studies by the same author, and in both of which cartilage was tested in the direction parallel to the collagen orientation in the surface layer. In the present work articular cartilage was tested also along the perpendicular direction, being the direction in which cartilage possesses lower tensile strength. Specimens were tested under cyclic tensile load. Number of cycles at failure was recorded as well as elongation of the specimen. To date 72 specimens have been tested all from one knee joint. The number of cycles to failure ranged between two and 1.5 million. The surface and deep layers have better fatigue properties whether tested in the parallel or the perpendicular direction, while the middle layer was far weaker. Better fatigue behaviour was observed with specimens tested in parallel than in perpendicular direction to the fibres.
authors.affiliation: Rheumatology and Rehabilitation Research Unit, University of Leeds, Leeds, UK.
authors.forename: Giordano
authors.initials: G
authors.lastname: Bellucci
authors.forename: Bahaa B
authors.initials: BB
authors.lastname: Seedhom
mesh_terms: D002358:Cartilage, Articular / Q000502:physiology*; D005221:Fatigue; D006801:Humans; D066298:In Vitro Techniques; D013314:Stress, Mechanical; D013718:Tensile Strength; D013997:Time Factors