Electrocatalytic response of dopamine at a metallothioneins self-assembled gold electrode.
The metallothioneins (MT) self-assembled monolayer modified gold electrode (MT/Au) is demonstrated to catalyze the electrochemical response of dopamine (DA) by cyclic voltammetry. A pair of well-defined redox waves was obtained and the calculated standard rate constant (k(s)) is 6.97 x 10(-3) cm s(-1) (20 degrees C) at the self-assembled electrode. The electrode reaction is a quasi-reversible process. The oxidation peak of DA can be used to determine the concentration of DA. The peak current and the concentration of DA follow a linear relationship in the range of 2.0 x 10(-5) M to 8.0 x 10(-4) M. The detection limit is 6.0 x 10-6 M. By ac impedance spectroscopy, the apparent electron transfer rate constant (k(app)) of Fe(CN)6(3-)/Fe(CN)6(4-) at the MT/Au electrode was obtained as 2.0 x 10(-5) cm s(-1). The MT/Au was characterized with grazing angle FT-IR spectroscopy and contact angle goniometry.
Wang
Qian
Q
Department of Chemistry, Peking University, Beijing, People's Republic of China.
Li
Nanqiang
N
Wang
Wenqing
W
D002384:Catalysis; D004298:Dopamine / Q000737:chemistry*; D017097:Electric Impedance; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes / Q000639:trends; D006046:Gold / Q000032:analysis / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008668:Metallothionein / Q000032:analysis / Q000737:chemistry*; D008956:Models, Chemical; D010084:Oxidation-Reduction; D017550:Spectroscopy, Fourier Transform Infrared
D006046:Gold; D008668:Metallothionein; D004298:Dopamine