Total synthesis of caerulomycin C via the halogen dance reaction.
[reaction: see text] The total synthesis of caerulomycin C is described. Key steps in this synthesis utilize 1,2-, 1,3-, and 1,4-halogen dance reactions for the functionalization of the pyridine ring.
Sammakia
Tarek
T
Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215, USA. sammakia@colorado.edu
Stangeland
Eric L
EL
Whitcomb
Mark C
MC
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D002384:Catalysis; D006219:Halogens / Q000737:chemistry; D007202:Indicators and Reagents; D013302:Streptomyces / Q000737:chemistry
D006219:Halogens; D007202:Indicators and Reagents; C043637:cerulomycin; D015082:2,2'-Dipyridyl