title: The impact of peripheral and coronary artery disease on health-related quality of life.
abstract: Vascular diseases, like peripheral arterial diseases (PAD) and coronary artery disease (CAD), are common diseases with a high morbidity. We investigated and compared the impact of these diseases on daily life using health-related quality of life (HRQOL) analysis. In 89 patients with PAD and 89 patients with multivessel CAD, the SF-36 was assessed before diagnostic staging and compared with an age-matched reference population. Both groups of patients had a significantly impaired HRQOL as compared to a reference population. Patients with PAD scored significantly (p < 0.001) lower than those with CAD on the domains general health perception, change in health, physical functioning, social functioning, and pain. Patients with PAD have a reduced HRQOL in comparison with patients with CAD. Each disease has an impact on a specific domain of the HRQOL. Vascular disease mainly influences physical health.
authors.affiliation: Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Jurgen C
authors.initials: JC
authors.lastname: de Graaff
authors.forename: Dirk Th
authors.initials: DT
authors.lastname: Ubbink
authors.forename: Elisabeth Ilse J C
authors.initials: EI
authors.lastname: Kools
authors.forename: Steven A J
authors.initials: SA
authors.lastname: Chamuleau
authors.forename: Michael J H M
authors.initials: MJ
authors.lastname: Jacobs
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003324:Coronary Artery Disease / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D016491:Peripheral Vascular Diseases / Q000453:epidemiology*; D011788:Quality of Life; D018434:Sickness Impact Profile