[Serum and urine total arsenic concentration in a case of acute arsenic intoxication].
The 68-year-old man took arsenic pasta 1 g (arsenic trioxide 0.45 g) to commit suicide and was admitted 16 hours after ingestion. He developed vomiting and coma, followed by pancytopenia. He was treated with activated charcoal, laxative, dimercaprol, sodium thiosulfate and direct hemoperfusion with good recovery. Total arsenic concentrations in serum and urine were 39 ng/ml and 89 ng/ml on admission, respectively. Urine arsenic concentration showed the second peak around 48 hours after admission.
Koyama
Kazuhiro
K
Department of Pharmacy, Institute for Clinical Research, National Tokyo Medical Center.
Tanaka
Keizi
K
Sakamoto
Namiko
N
Kikuno
Takaaki
T
Shimazu
Yoko
Y
Kaziwara
Hirosi
H
Sekiguti
Hisanori
H
D000208:Acute Disease; D000368:Aged; D001151:Arsenic / Q000097:blood* / Q000652:urine*; D020261:Arsenic Poisoning / Q000378:metabolism* / Q000628:therapy*; D006801:Humans; D008297:Male; D013406:Suicide, Attempted; D013997:Time Factors; D016896:Treatment Outcome
D001151:Arsenic