title: p53 and anti-p53 antibodies as possible markers of a switch towards a neoplastic phenotype in patients infected by Helicobacter pylori.
abstract: Helicobacter pylori is a definite carcinogen whose mechanism of action is still unknown. The aim of this work was (1) to determine the presence of p53 protein and related antibodies in patients affected by various gastric pathologies and chronically infected with H. pylori, and (2) to try to discover a test to be used as a marker of a possible switch towards a neoplastic phenotype.
authors.affiliation: Istituto Nazionale per la Ricerca sul Cancro - Genova, Unità Satellite di Messina, Messina, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Losi
authors.forename: A M
authors.initials: AM
authors.lastname: Molinari
authors.forename: P
authors.initials: P
authors.lastname: Gazzerro
authors.forename: L
authors.initials: L
authors.lastname: Ortega De Luna
authors.forename: M T
authors.initials: MT
authors.lastname: Fera
authors.forename: M
authors.initials: M
authors.lastname: Carbone
authors.forename: M R
authors.initials: MR
authors.lastname: Catania
authors.forename: D L
authors.initials: DL
authors.lastname: Hasty
authors.forename: F
authors.initials: F
authors.lastname: Rossano
mesh_terms: D000906:Antibodies / Q000276:immunology; D002471:Cell Transformation, Neoplastic / Q000276:immunology / Q000378:metabolism*; D016481:Helicobacter Infections / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology*; D016480:Helicobacter pylori; D006801:Humans; D010641:Phenotype; D016159:Tumor Suppressor Protein p53 / Q000276:immunology / Q000378:metabolism*
chemical_list: D000906:Antibodies; D016159:Tumor Suppressor Protein p53