title: Economic analysis of the 1992-1993 mass immunization campaign against serogroup C meningococcal disease in Quebec.
abstract: The objective of the study was to evaluate the cost-effectiveness and utility of the mass immunization campaign performed in the province of Quebec in 1992-1993, following an outbreak of serogroup C meningococcal disease (CMD). Effectiveness data were extracted from a population-based cohort study, and cost estimates were obtained from surveys. Costs of the campaign to the health system were $ 26 million (1993 Canadian dollars). Between 48 and 74 CMD cases, and between 7 and 11 deaths were prevented in the following 5 years. Net societal costs were between $ 18 and 21 million (using a 3% discount rate), net costs per death averted were between $ 1.7 and 3.0 million, between $ 58,000 and 105,000 per life-year gained, and between $ 49,000 and 87,000 per quality-adjusted life-year gained. These economic indices are less favorable than those for current routine immunization programs in Canada, but within the range of those for other common health interventions.
authors.affiliation: Department of Community Health Sciences, University of Sherbrooke, 3001 12th Avenue North, Sherbrooke, Quebec, Canada J1H 5N4. Philippe.Dewals@msp.ulaval.ca
authors.forename: Philippe
authors.initials: P
authors.lastname: De Wals
authors.forename: Lonny
authors.initials: L
authors.lastname: Erickson
mesh_terms: D015331:Cohort Studies; D003153:Community Health Services / Q000191:economics*; D003362:Cost-Benefit Analysis; D017048:Health Care Costs; D006801:Humans; D007114:Immunization; D032541:Mass Vaccination / Q000191:economics / Q000379:methods*; D008589:Meningococcal Infections / Q000191:economics / Q000453:epidemiology / Q000517:prevention & control*; D022401:Meningococcal Vaccines / Q000008:administration & dosage / Q000191:economics*; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D011792:Quebec / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D022401:Meningococcal Vaccines; D011135:Polysaccharides, Bacterial