[The effect of argon-containing hypoxic gas environment on development of Japanese quail embryos].
In case of acute hypoxic hypoxia argon in the gas environment is favorable to survivability of laboratory animals (rats). Our purpose was to evaluate effects of an argon-containing hypoxic gas environment on embryogenesis of the Japanese quail (Cortunix cortunix japonica). Eggs of the Japanese quail were incubated in a pressurized chamber with a hypoxic gas environment differing in concentration of nitrogen and argon. In hypoxic (10% O2) oxygen-nitrogen and oxygen-nitrogen-argon atmospheres total mortality of embryos was observed no later than on day 7 of development. These gas mixtures also had a teratogenic effect. However, about 55% of argon in atmosphere prevented completely microcephalia and reduced in half incidence of other pathologies.
Soldatov
P E
PE
Dadasheva
O A
OA
Gur'eva
T S
TS
Lysenko
L A
LA
Remizova
S E
SE
D000818:Animals; D001128:Argon / Q000032:analysis* / Q000494:pharmacology; D003370:Coturnix / Q000196:embryology*; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D000860:Hypoxia / Q000503:physiopathology*; D008831:Microcephaly / Q000517:prevention & control; D009584:Nitrogen / Q000032:analysis* / Q000494:pharmacology
D001128:Argon; D009584:Nitrogen