The use of topical nitroglycerin ointment to treat peripheral tissue ischemia secondary to arterial line complications in neonates.
Catheterization of the aorta through the umbilical artery and/or of peripheral arteries in neonates may be accompanied by a number of complications, of which thrombotic phenomena and peripheral vasospasm are the most common. Two neonates with peripheral ischemia caused by vasospasm from indwelling umbilical artery catheterization and one infant with left hand ischemia due to a left radial artery line were successfully treated with 2% nitroglycerin ointment. No adverse effects were noted.
Baserga
Mariana C
MC
Division of Neonatology, Department of Pediatrics, Cedars-Sinai Medical Center, and UCLA School of Medicine, Los Angeles, CA, USA.
Puri
Asha
A
Sola
Augusto
A
D002406:Catheterization, Peripheral / Q000009:adverse effects*; D002408:Catheters, Indwelling / Q000009:adverse effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007511:Ischemia / Q000188:drug therapy*; D008297:Male; D005996:Nitroglycerin / Q000008:administration & dosage*; D009824:Ointments; D014469:Umbilical Arteries; D014665:Vasodilator Agents / Q000008:administration & dosage*
D009824:Ointments; D014665:Vasodilator Agents; D005996:Nitroglycerin