[Diaphragmatic hernia from 1961 to 2000--incidence, prenatal diagnosis and prevalence according to maternal age].
OBJECTIVE
Presentation of diaphragmatic hernia in the CR in 1961-2000. Analysis of prevalence of these defects in different groups by maternal age.


METHODS
Retrospective demographic-epidemiological study.


METHODS
Institute for the Care of Mother and Child, Prague.


METHODS
The authors used data from nationwide registers of birth defects in neonates kept in the Institute of Health Information and Statistics of the CR during 1995-2000. Epidemiological analysis of the incidence of diaphragmatic hernia in the CR during 1961-2000 in newborn infants. Mathematical statistical analysis of prevalence of these defects by maternal age using the method of 95% confidence interval of probability.


RESULTS
In the CR during 1961-2000 1321 cases of diaphragmatic hernia were recorded. The mean incidence of this defect during the entire period was 2.32 per 10,000 live born infants incl. prenatally diagnosed cases and terminated pregnancies. Including those it was 2.37 per 10,000 live born infants.


CONCLUSIONS
The authors elaborated the mean incidence during the investigation period and in individual years in born children as well as prenatally diagnosed cases. Also an analysis of the prevalence of these defects by maternal age was made using the method of 95% confidence interval. The authors found a significantly higher risk of development of this defect in foetuses of women aged 38, 42 years or older as compared with the population average. However an unequiwocally increased risk associated with more advanced age was neither confirmed nor ruled out.
Sípek
A
A
Ustav pro péci o matku a dítĕ, Praha-Podolí.
Gregor
V
V
Horácek
J
J
Masátová
D
D
D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006548:Hernia, Diaphragmatic / Q000175:diagnosis / Q000453:epidemiology*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008423:Maternal Age; D011247:Pregnancy; D011296:Prenatal Diagnosis; D015995:Prevalence; D012189:Retrospective Studies