title: Layered paving of vesicular nanoparticles formed with cerasome as a bioinspired organic-inorganic hybrid.
abstract: A three-dimensional packed vesicular assembly was successfully prepared by using an organic-inorganic hybrid, the Cerasome. This assembly was achieved by using an alternate layer-by-layer adsorption technique with the anionic and the cationic Cerasome derived from corresponding organoalkoxysilane amphiphiles. Adsorption quantities of each Cerasome layer were evaluated by employing a quartz crystal microbalance. The surface structure of the Cerasome paving on a substrate obtained in this way was observed by atomic force microscopy. The Cerasome particles closely packed like a stone pavement were clearly observed in both layers. In addition, the difference in the particle size for each layer indicates the cationic and anionic Cerasomes undoubtedly formed the layer-by-layer assembly. The layered paving of the vesicular nanoparticles was seen in every layer at least up to ten adsorption steps.
authors.affiliation: Graduate School of Materials Science, Nara Institute of Science and Technology (NAIST), 8916-5 Takayama, Ikoma, Nara 630-0101, Japan.
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Katagiri
authors.forename: Ryo
authors.initials: R
authors.lastname: Hamasaki
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Ariga
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kikuchi
mesh_terms: D002516:Ceramics / Q000737:chemistry*; D008051:Lipid Bilayers / Q000138:chemical synthesis* / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry; D036103:Nanotechnology; D010316:Particle Size
chemical_list: D008051:Lipid Bilayers; D008081:Liposomes