[Interleukin 12 (IL-12) and its receptor].
This article reviews of recent data on the structure of IL-12 and the function of its receptor (IL-12R). It presents a new opinion on the role of its subunits in the cytokine activity and on the signal transmission via IL-12R in the process of cell activation by IL-12.
Szeliga
Jacek
J
Katedra Immunologii Instytutu Mikrobiologii i Immunologii Uniwersytetu Łódzkiego. szelj@biol.uni.lodz.pl
Gościcka
Teresa
T
D000818:Animals; D001711:Biotransformation; D006801:Humans; D018664:Interleukin-12 / Q000737:chemistry / Q000378:metabolism*; D018123:Receptors, Interleukin / Q000378:metabolism*; D053707:Receptors, Interleukin-12; D015398:Signal Transduction
D018123:Receptors, Interleukin; D053707:Receptors, Interleukin-12; D018664:Interleukin-12