title: The importance of HLA DQB1*0602 typing in Slovene patients with narcolepsy.
abstract: The HLA class II region genes DQB1*0602 and DQA1*0102 are currently the best genetic predictors for narcolepsy in humans (1(. The aim of this study was to identify the HLA DQ alleles (DQB1*0602 and DQA1*0102) in Slovene sporadic narcoleptic patients. 11 patients who fulfilled ICSD criteria for narcolepsy entered the study. DRB1*1501 DQB1*0602 was present in all the patients while DQA1*0102 was absent in 2 patients. We propose that DQB1*0602 typing is important in diagnosing narcolepsy in Slovene patients
authors.affiliation: Institute of Clinical Neurophysiology, Division of Neurology, University Medical Centre, Ljubljana, Slovenia.
authors.forename: Leja
authors.initials: L
authors.lastname: Dolenc-Grosel
authors.forename: David B
authors.initials: DB
authors.lastname: Vodusek
mesh_terms: D006683:HLA-DQ Antigens / Q000145:classification* / Q000235:genetics; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; D006650:Histocompatibility Testing; D006801:Humans; D009290:Narcolepsy / Q000175:diagnosis / Q000235:genetics / Q000276:immunology*; D017524:Slovenia
chemical_list: D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; D059866:HLA-DQ beta-Chains; C069050:HLA-DQA1 antigen; C069051:HLA-DQB1 antigen