[Morphological characteristics of cell populations in bronchial biopsy from mining-chemical factory workers].
A clinicomorphological examination of bronchial and transbronchial biopsies from the workers of a mining and chemical enterprise in Zheleznogorsk has demonstrated that long-term exposure to low-dose radionuclide radiation induces essential inflammatory and scleroticatrophic changes in the bronchopulmonary tissue. All the cell populations of the bronchial epithelium and stroma as well as a respiratory part of the lungs are involved into the pathological process. Squamous metaplasia of the bronchial epithelium is observed in 50% cases, in half of them various dysplastic processes occur. The complex of the above morphological alterations evidences for an oncological trend in pathological processes in the lungs of workers exposed to radionuclides.
Ali-Riza
A E
AE
Research Institute of Human Morphology, 117418, Moscow.
Barkhina
T G
TG
Samsonova
M V
MV
Cherniaev
A L
AL
D001706:Biopsy; D001980:Bronchi / Q000473:pathology* / Q000528:radiation effects; D004847:Epithelial Cells / Q000473:pathology / Q000528:radiation effects; D006801:Humans; D008168:Lung / Q000473:pathology* / Q000528:radiation effects; D008175:Lung Neoplasms / Q000209:etiology; D008906:Mining; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D016273:Occupational Exposure; D011829:Radiation Dosage; D011850:Radioactive Waste / Q000009:adverse effects; D012426:Russia
D011850:Radioactive Waste