Genetic epidemiology. Psoriatic arthritis.
The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis. However, a distinct entity is likely to have distinct susceptibility factors in addition to those that contribute to psoriasis and inflammatory arthritis alone. These aetiological factors may be genetic and/or environmental, and in this review, the evidence for distinct psoriatic arthritis genetic susceptibility factors is considered.
Barton
Anne C
AC
Arthritis Rheumatism Campaign Epidemiology Research Unit, University of Manchester, UK. ABarton@fs1.ser.man.ac.uk
D015535:Arthritis, Psoriatic / Q000453:epidemiology* / Q000235:genetics*; D008040:Genetic Linkage; D020022:Genetic Predisposition to Disease; D006801:Humans; D017720:Molecular Epidemiology