title: Elastographic imaging using a handheld compressor.
abstract: Elastography is an emerging imaging modality that allows noninvasive imaging of tissue stiffness changes and stiffness values associated with pathology or as a result of therapy. However, many currently-used systems for elastography rely on a fixed geometry transducer and compressor system for imaging. This configuration is disadvantageous for imaging difficult-to-reach regions that are currently accessible with conventional ultrasound. In this paper, we describe a handheld, portable stepper motor controlled system for elastography. This system may reduce motion and jitter errors that are prevalent in completely 'freehand elastography' that employs hand-induced compressions using the transducer. The latter also requires collection of large amounts of data and use of strain estimation algorithms that may not be sensitive to phase changes or use additional preprocessing to minimize decorrelation effects. The stepper motor controlled handheld system provides controlled compressions and synchronized data acquisition. Our technique yields elastograms of a low-contrast phantom that have contrast levels and contrast-to-noise ratios that are comparable to those obtained with a fixed geometry system.
authors.affiliation: Department of Medical Physics, The University of Wisconsin-Madison, 53706, USA. tvarghese@facstaff.wisc.edu
authors.forename: T
authors.initials: T
authors.lastname: Varghese
authors.forename: J A
authors.initials: JA
authors.lastname: Zagzebski
authors.forename: G
authors.initials: G
authors.lastname: Frank
authors.forename: E L
authors.initials: EL
authors.lastname: Madsen
mesh_terms: D000818:Animals; D004285:Dogs; D004548:Elasticity; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D019047:Phantoms, Imaging; D014159:Transducers; D014463:Ultrasonography / Q000295:instrumentation* / Q000379:methods