Fatal Saccharomyces cerevisiae aortic graft infection.
Saccharomyces cerevisiae is a yeast commonly used in baking and a frequent colonizer of human mucosal surfaces. It is considered relatively nonpathogenic in immunocompetent adults (J. N. Aucott, J. Fayan, H. Grossnicklas, A. Morrissey, M. M. Lederman, and R. A. Salata, Rev. Infect. Dis. 12:406-411, 1990). We present a case of S. cerevisiae fungemia and aortic graft infection in an immunocompetent adult. This is the first reported case of S. cerevisiae fungemia where the identity of the pathogen was confirmed by rRNA sequencing.
Smith
Davey
D
Departments of Medicine, University of California at San Diego, La Jolla, California 92093, USA. d13smith@ucsd.edu
Metzgar
David
D
Wills
Christopher
C
Fierer
Joshua
J
D001012:Aorta, Abdominal / Q000637:transplantation*; D017809:Fatal Outcome; D016469:Fungemia / Q000209:etiology / Q000382:microbiology; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000209:etiology* / Q000382:microbiology; D010802:Phylogeny; D012331:RNA, Fungal / Q000235:genetics; D012337:RNA, Ribosomal, 18S / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*
D012331:RNA, Fungal; D012337:RNA, Ribosomal, 18S