Cell lineage specification in the nervous system.
Nervous system development requires the specification of numerous neural stem cells. Subsequently these stem cells divide in a spatially and temporally controlled manner to generate the diverse cell types found in the different layers of the nervous system. Lineage specification is brought about by transcriptional regulators, which often act as transcriptional repressors.
Edenfeld
Gundula
G
Institut für Neurobiologie, Universität Münster, Badestr. 9, 48149 Münster, Germany.
Pielage
Jan
J
Klämbt
Christian
C
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D004330:Drosophila / Q000196:embryology; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D051379:Mice; D009420:Nervous System / Q000196:embryology*; D013234:Stem Cells / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology; D014158:Transcription, Genetic / Q000502:physiology
D014157:Transcription Factors