Phosphine-catalyzed annulation of thioamides and 2-alkynoates: a new synthesis of thiazolines.
The annulation of thioamides with 2-alkynoates and 2,3-dienoates under the catalysis of tri-n-butylphosphine was described. The annulation reaction provided a new entry to thiazolines, particularly those with 2-aryl substituents.
Liu
Bing
B
Chemical Development, GlaxoSmithKline, Five Moore Drive, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398, USA. bl10520@gsk.com
Davis
Roman
R
Joshi
Biren
B
Reynolds
Daniel W
DW