An unusual case of osteoblastic metastasis from gastric carcinoma.
We report an unusual case of osteoblastic metastasis from gastric carcinoma. In this case, bone metastasis was the initial manifestation of the cancer. The laboratory findings revealed mild hypocalcemia and markedly elevated alkaline phosphatase levels. Plain X-ray showed mottled osteoblastic changes in the pelvis. Bone marrow and bone biopsy of the pelvis revealed metastatic adenocarcinoma with increased osteoblastic activity. An extensive search for the primary site revealed advanced gastric carcinoma, which was confirmed by endoscopic biopsy.
Chung
Yoon-Sok
YS
Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea. yschung@madang.ajou.ac.kr
Choi
Tae-Young
TY
Ha
Chang-Young
CY
Kim
Hyeon-Man
HM
Lee
Kwang-Jae
KJ
Park
Chan H
CH
Fitzpatrick
Lorraine A
LA
D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D010006:Osteoblasts / Q000000981:diagnostic imaging; D010388:Pelvis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013274:Stomach Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed