title: Cell lineage specification in the nervous system.
abstract: Nervous system development requires the specification of numerous neural stem cells. Subsequently these stem cells divide in a spatially and temporally controlled manner to generate the diverse cell types found in the different layers of the nervous system. Lineage specification is brought about by transcriptional regulators, which often act as transcriptional repressors.
authors.affiliation: Institut für Neurobiologie, Universität Münster, Badestr. 9, 48149 Münster, Germany.
authors.forename: Gundula
authors.initials: G
authors.lastname: Edenfeld
authors.forename: Jan
authors.initials: J
authors.lastname: Pielage
authors.forename: Christian
authors.initials: C
authors.lastname: Klämbt
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D004330:Drosophila / Q000196:embryology; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D051379:Mice; D009420:Nervous System / Q000196:embryology*; D013234:Stem Cells / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology; D014158:Transcription, Genetic / Q000502:physiology
chemical_list: D014157:Transcription Factors