Whipple's resection-proximal pancreaticoduodenectomy (PD).
Pancreatic resection offers the potential for long-term cure in 15% of patients with pancreatic cancer. This article describes the author's technique of pancreaticoduodenectomy (PD), together with guidelines for disease staging, pre-operative work-up and patient selection. The role of neo-adjuvant and adjuvant chemotherapy is currently under evaluation and all patients who have a curative resection should be considered for entry into the ESPAC 3 trial that aims to establish the definitive role of adjuvant chemotherapy in pancreatic cancer.
Department of Surgery & Molecular Oncology, Ninewells Hospital & Medical School, Dundee, UK. i.z.tait@dundee.ac.uk
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D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery*; D000465:Algorithms; D003131:Combined Modality Therapy; D004066:Digestive System Diseases / Q000473:pathology / Q000601:surgery; D006801:Humans; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000009:adverse effects* / Q000379:methods*; D018579:Patient Selection; D019990:Perioperative Care / Q000379:methods; D011183:Postoperative Complications