[Pharmacologically-induced hypertension in a patient with vertebro-basilar territory ischemia associated with bilateral vertebral stenosis].
Hypertension is one of the main risk factors for stroke. However, treating hypertension in the acute phase may cause further neurological deterioration. We present a case of an 81-year-old woman, admitted after multiple infarcts in the posterior circulation. While fully anticoagulated, her neurological deficits worsened, coinciding with normalization of her blood pressure levels. Magnetic resonance angiography documented bilateral vertebral artery stenoses. Induced hypertension was followed by rapid clinical improvement. In this first report of induced hypertension in the Brazilian literature, we illustrate the potential benefit of this therapeutic strategy in patients with documented hemodynamic mechanism of clinical deterioration.
Oliveira-Filho
Jamary
J
Serviço de Neurologia, Hospital São Rafael, Fundação Monte Tabor, Salvador, BA, Brasil.
Pedreira
Bruno B
BB
Jesus
Pedro A P
PA
Souza
Paulo E M
PE
Bacellar
Aroldo S
AS
D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000009:adverse effects; D002316:Cardiotonic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002544:Cerebral Infarction / Q000188:drug therapy; D004298:Dopamine / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D012307:Risk Factors; D014715:Vertebrobasilar Insufficiency / Q000188:drug therapy*
D000959:Antihypertensive Agents; D002316:Cardiotonic Agents; D004298:Dopamine