Okadaic acid-induced EGF receptor and MAP kinase activation does not require reactive oxygen species in primary keratinocytes.
Medical School, Heinrich Heine University, Universitätsstrasse 1, 40225 Düsseldorf, Germany. meves@uni-duesseldorf.de
Alexander
A
Meves
Dominik
D
Peus
Mark R
MR
Pittelkow
D002273:Carcinogens / Q000633:toxicity; D002478:Cells, Cultured; D004789:Enzyme Activation / Q000187:drug effects; D066246:ErbB Receptors / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D006801:Humans; D015603:Keratinocytes / Q000187:drug effects* / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D019319:Okadaic Acid / Q000633:toxicity*; D011799:Quinazolines / Q000494:pharmacology; D017382:Reactive Oxygen Species / Q000378:metabolism*
D002273:Carcinogens; D011799:Quinazolines; D017382:Reactive Oxygen Species; D019319:Okadaic Acid; D066246:ErbB Receptors; D020928:Mitogen-Activated Protein Kinases; C088860:4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline