A randomised controlled trial of the closure or non-closure of peritoneum at caesarean section: effect on post-operative pain.
OBJECTIVE
To compare the analgesic requirement in the post-operative period after closure or non-closure of the peritoneum at the caesarean delivery with a standardised anaesthetic and surgical technique.


METHODS
A randomised double-blind controlled trial was performed on 100 women who underwent elective caesarean delivery.


METHODS
Analgesic requirement assessed by morphine usage via patient controlled analgesia pump over the first 24-hour period after surgery, oral analgesia used during the first four days, postoperative pain assessed by a visual analogue scale and a verbal rating scale, and patient satisfaction assessed by verbal rating scale were the main outcome measures.


RESULTS
Pain scores at 24 hours were similar in both groups (43.5 in closure and 40.5 in non-closure) but during the first 24 hours the non-closure group had used significantly less morphine than the closure group (0.64 mg/kg of body weight vs 0.82 mg/kg, P = 0.04). The patients in non-closure group had significantly higher satisfaction scores after 24 hours than the closure group.


CONCLUSIONS
Non-closure of both visceral and parietal peritoneum at the caesarean section produces a significant reduction in the post-operative use of patient controlled analgesia pump morphine and significantly higher patient satisfaction at 24 hours post-operatively.
Department of Anaesthetics, Castle Hill Hospital, Hull, UK.
Z
Z
Rafique
K U
KU
Shibli
I F
IF
Russell
S W
SW
Lindow
D000328:Adult; D016362:Analgesia, Obstetrical / Q000379:methods; D016058:Analgesia, Patient-Controlled / Q000295:instrumentation; D000701:Analgesics, Opioid / Q000008:administration & dosage; D002585:Cesarean Section / Q000379:methods*; D004311:Double-Blind Method; D004333:Drug Administration Routes; D017558:Elective Surgical Procedures / Q000379:methods; D005260:Female; D006801:Humans; D007902:Length of Stay; D009020:Morphine / Q000008:administration & dosage; D010147:Pain Measurement; D010149:Postoperative Pain / Q000209:etiology* / Q000517:prevention & control; D017060:Patient Satisfaction; D010537:Peritoneum / Q000601:surgery*; D011247:Pregnancy
D000701:Analgesics, Opioid; D009020:Morphine