A modified molecular beacon combining the properties of TaqMan probe.
A modified molecular beacon that possesses a stem-hairpin structure as seen in conventional molecular beacons and can be cleaved during PCR in designed, and it can specifically recognize the presence of the target and was obviously more sensitive than conventional molecular beacons.
State Key Lab of Functional Polymer Materials for Adsorption and Separation, Chemical School, Nankai University, Tianjin 300071, China.
De-Ming
DM
Kong
Long
L
Gu
Han-Xi
HX
Shen
Huai-Feng
HF
Mi
D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D015342:DNA Probes / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D006515:Hepatitis B virus / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D009841:Oligonucleotides / Q000737:chemistry / Q000378:metabolism*; D016133:Polymerase Chain Reaction / Q000379:methods*; D012680:Sensitivity and Specificity
D015342:DNA Probes; D005456:Fluorescent Dyes; D009841:Oligonucleotides; D004247:DNA