Severe hypoglycaemia associated with a giant solitary fibrous tumor of the pleura.
Solitary fibrous tumors (SFT) of the pleura are a rare neoplasm, with benign biological behaviour. Recurrences are rare, and no distant metastases are described in the literature. SFT can secrete hormone-like substances, responsible for paraneoplastic syndromes. The authors describe a case of severe hypoglycaemia due to insulin-like growth factor II (IGF-2)'s secretion by a giant SFT of the pleura. Hypoglycaemia was controlled by the resection of the tumor. Diagnosis and surgical management of these neoplasms are also discussed.
Filosso
P L
PL
Department of Thoracic Surgery, University of Torino, San Giovanni Battista Hospital, Italy. pierluigifilosso@tiscalinet.it
Oliaro
A
A
Rena
O
O
Papalia
E
E
Ruffini
E
E
Mancuso
M
M
D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007335:Insulin-Like Growth Factor II / Q000378:metabolism; D008297:Male; D008654:Mesothelioma / Q000150:complications* / Q000378:metabolism / Q000601:surgery; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D010997:Pleural Neoplasms / Q000150:complications* / Q000378:metabolism / Q000601:surgery
D007335:Insulin-Like Growth Factor II