Cloning and developmental expression of AmphiBrn1/2/4, a POU III gene in amphioxus.
The large family encoding POU transcription factors has been described in several species. In particular, class III POU genes regulate critical steps of vertebrate and invertebrate neurogenesis. A novel amphioxus class III POU gene, AmphiBrn1/2/4, has been isolated and its spatio-temporal expression has been reported. AmphiBrn1/2/4 is first expressed in the dorsal epiblast, then throughout the neural plate except for a gap at level of the anterior region of the cerebral vesicle. Transcripts are also detected in the primordium of gill slits, pharynx and left Hatschek's diverticulum.
Dipartimento di Biologia Sperimentale, Ambientale e Applicata, Università di Genova, viale Benedetto XV 5, Italy.
Simona
S
Candiani
Patrizio
P
Castagnola
Diana
D
Oliveri
Mario
M
Pestarino
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002816:Chordata, Nonvertebrate / Q000196:embryology / Q000235:genetics* / Q000254:growth & development*; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D007814:Larva / Q000235:genetics / Q000254:growth & development; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000235:genetics*
D018076:DNA, Complementary; D014157:Transcription Factors