Burkholderia gladioli keratitis associated with consecutive recurrent endophthalmitis.
OBJECTIVE
To report a case of Burkholderia gladioli keratitis with consecutive endophthalmitis.


METHODS
Case report and literature review.


RESULTS
A 76-year-old man with a history of diabetes mellitus developed bacterial keratitis and consecutive endophthalmitis in the corneal graft of the left eye. Corneal, aqueous, and vitreous cultures yielded Burkholderia gladioli. Emergent keratoplasty, pars plana vitrectomy, and injection of intravitreal antibiotics led to resolution of the infection and improved vision. Four months later, the patient developed recurrent Burkholderia keratitis and endophthalmitis, necessitating a total keratoplasty and repeat injection of intravitreal antibiotics.


CONCLUSIONS
This is the first report, to our knowledge, of ocular Burkholderia gladioli infection, an uncommon aerobic, gram-negative rod, recently subclassified from the genus Pseudomonas based on DNA-rRNA homology studies.
Department of Ophthalmology, New York Eye and Ear Infirmary, 310 E. 14th Street, New York, NY 10003, U.S.A. ritterband@msn.com
David
D
Ritterband
Mahendra
M
Shah
Kenneth
K
Cohen
Joy
J
Lawrence
John
J
Seedor
D000368:Aged; D019117:Burkholderia / Q000302:isolation & purification; D019121:Burkholderia Infections / Q000188:drug therapy / Q000473:pathology; D016039:Corneal Transplantation; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D012008:Recurrence