Digestive system involvement in cystic fibrosis.
Cystic fibrosis is a hereditary disease well known to paediatricians. Over recent years, its prevalence among the adult population has dramatically increased; thus becoming a disease increasingly seen in adult practice. Cystic fibrosis is a multi-organ disease, with a wide spectrum of clinical manifestations involving many organs. The aim of this article is to review the digestive system manifestations of this disease: the involvement of the gastrointestinal tract, liver, biliary system and pancreas, with a special emphasis on the adult population.
Modolell
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Digestive System Research Unit, Hospital Vall d'Hebrón, Autonomous University of Barcelona, Paseo Vall d'Hebrón 119-129, E-08035 Barcelona, Spain.
Guarner
L
L
Malagelada
J R
JR
D001659:Biliary Tract / Q000503:physiopathology; D003550:Cystic Fibrosis / Q000150:complications* / Q000235:genetics / Q000503:physiopathology; D004066:Digestive System Diseases / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology; D006801:Humans; D008099:Liver / Q000503:physiopathology; D010179:Pancreas / Q000503:physiopathology