Perilymphatic pressure measurement in Meniere's disease.
The aim of this study was to evaluate the perilymphatic pressure, by means of the MMS-10 Tympanic Displacement Analyzer (TDA), in patients with Meniere's disease (MD). Measurements were performed in 37 patients with MD and in 14 normal-hearing subjects. Data were collected from 3 groups: healthy ears of normal-hearing subjects, unaffected ears of patients with MD, and affected ears of patients with MD. Analysis of the results obtained with the TDA showed no significant differences between the 3 groups. Several hypotheses could explain this lack of difference: 1) perhaps indirect measurement of perilymphatic pressure with the TDA is not relevant; 2) perhaps hyperpressure of the inner ear is not the physiological basis for the clinical triad of MD; or 3) perhaps endolymphatic hydrops does not produce changes in perilymphatic pressure. The results of this series indicate that the TDA is not useful in the evaluation of patients with MD.
Department of Otorhinolaryngology, Fondation Adolphe de Rothschild, Paris, France.
Denis
D
Ayache
Isabelle
I
Plouin-Gaudon
Kemal
K
Bouzerar
Pierre
P
Elbaz
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008575:Meniere Disease / Q000175:diagnosis / Q000503:physiopathology*; D008875:Middle Aged; D010498:Perilymph / Q000502:physiology*; D011312:Pressure; D012720:Severity of Illness Index