Plumieride from Allamanda cathartica as an antidermatophytic agent.
Plumieride has been isolated as an active principle of the leaves of Allamanda cathartica. It showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. It exhibited a noncytotoxic nature against a P(388) mouse leukaemia cell line.
Tiwari
T N
TN
Department of Botany, Banaras Hindu University, Varanasi 221005, India.
Pandey
V B
VB
Dubey
N K
NK
D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D029062:Apocynaceae / Q000737:chemistry*; D002455:Cell Division / Q000187:drug effects; D003881:Dermatomycoses / Q000473:pathology*; D004821:Epidermophyton / Q000187:drug effects; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006801:Humans; D020128:Inhibitory Concentration 50; D007941:Leukemia P388 / Q000473:pathology; D051379:Mice; D008864:Microsporum / Q000187:drug effects; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D000935:Antifungal Agents; D005663:Furans; D010936:Plant Extracts; D013141:Spiro Compounds; C110080:plumieride