The Peters' plus syndrome: a review.
Peters' plus syndrome is an infrequently described entity that combines anomalies in the anterior chamber of the eye with other multiple congenital anomalies, and a developmental delay. Major symptoms are extremely variable anterior chamber anomalies, cupid bow of the upper lip, cleft lip and palate, short stature, broad hands and feet, and variable mental delay. The syndrome follows an autosomal recessive pattern of inheritance. The etiology is unknown, but may involve abnormal neural crest development. A review of the pertinent literature is provided.
Maillette de Buy Wenniger-Prick
Liesbeth J J M
LJ
Department of Ophthalmology, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands.
Hennekam
Raoul C M
RC
D000015:Abnormalities, Multiple / Q000235:genetics*; D000867:Anterior Chamber / Q000002:abnormalities*; D002971:Cleft Lip / Q000235:genetics*; D002972:Cleft Palate / Q000235:genetics*; D005124:Eye Abnormalities / Q000235:genetics*; D006130:Growth Disorders / Q000235:genetics*; D006801:Humans; D001523:Mental Disorders / Q000235:genetics; D013577:Syndrome