Exogenous lipoid pneumonia following ingestion of liquid paraffin.
An asymptomatic patient with exogenous lipoid pneumonia (ELP) due to silent aspiration of liquid paraffin ingested as a lubricant was diagnosed by bronchoalveolar lavage (BAL). BAL fluid separated into oily upper phase and lower aqueous phase spontaneously. Microscopic analysis of BAL cells revealed the presence of lipid-laden alveolar macrophages. Classic histochemical staining and electron microscope examination indicated that neutral lipid was dominant but phospholipid was also present in the lipid-laden macrophages. Together with the history of ingestion of liquid paraffin, we identified that the ingested liquid paraffin was the origin of the neutral lipid in the lipid-laden macrophages observed in the BAL fluid.
Ohwada
Akihiko
A
Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo.
Yoshioka
Yasuko
Y
Shimanuki
Yuri
Y
Mitani
Keiko
K
Kumasaka
Toshio
T
Dambara
Takashi
T
Fukuchi
Yoshinosuke
Y
D000328:Adult; D001992:Bronchoalveolar Lavage Fluid; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D016676:Macrophages, Alveolar / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D010232:Paraffin / Q000009:adverse effects*; D011017:Pneumonia, Lipid / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D013902:Radiography, Thoracic; D012597:Sclerosing Solutions / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D012597:Sclerosing Solutions; D010232:Paraffin