Severe angioedema induced by angiotensin converting enzyme inhibitors: role of precipitating factors.
Angiotensin converting enzyme inhibitors like captopril, enalapril, lisinopril, trandopril and ramipril may rarely induce a life threatening angioedema. We present two cases of severe angioedema induced by enalapril and ramipril along with possible precipitating factors observed in these patients. The importance of prompt recognition and early management of such cases is emphasized.
Department of Dermatology and Venereology, Government Medical College and Hospital, Chandigarh, India.
Sukhjot
S
Kaur
Gurvinder P
GP
Thami
Vadivelu
V
Srinivasan
Ram
R
Singh
Amrinder J
AJ
Kanwar
D000368:Aged; D000799:Angioedema / Q000139:chemically induced* / Q000188:drug therapy; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D004656:Enalapril / Q000009:adverse effects* / Q000627:therapeutic use; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D015985:Precipitating Factors; D017257:Ramipril / Q000009:adverse effects* / Q000627:therapeutic use; D013566:Sympathomimetics / Q000627:therapeutic use
D000806:Angiotensin-Converting Enzyme Inhibitors; D013566:Sympathomimetics; D004656:Enalapril; D017257:Ramipril; D006854:Hydrocortisone; D004837:Epinephrine