Extracts of Anacardium occidentale (cashew) pollen in patients with allergic bronchial asthma.
Allergic reactions to the pollen of trees is among the most prevalent allergic sensitivities. The cashew tree grows in abundance in the northeast region of the Brazil, mainly in Fortaleza city, in state of the Ceará. It flowers once a year between August and October. This is the first study conducted to establish the possible role of the cashew pollen extract in causing skin test reactivity in patients with allergic asthma. A stock solution of pollen extract was prepared with the standard weight/volume method for intradermal skin tests and for the protein content of the extract, estimated with the use of Folin phenol reagent and a spectrophotometer. Ten nonallergic volunteers and 80 subjects with allergic asthma, as documented by previous positive skin test reactions to various pollens, were studied. All of the 80 patients (100%) had positive test reactions (grade III and grade IV reactions). None of the control subjects (n = 10) had positive responses to the intradermal tests. This study provided us with knowledge of an additional pollen extract of the Anacardium occidentale, which could provoke skin test reactivities in asthmatic individuals from the northeastern area of Brazil. The results suggest a relationship between the period of flowering of the cashew tree and the increased number of allergic asthma cases.
Menezes
E A
EA
Department of Clinical Analyses, Faculty of Pharmacy, Universidade Federal do Ceará, Fortaleza, Brazil. menezes@ufc.br
Tomé
E R
ER
Nunes
R N
RN
Nunes
A P
AP
Freire
C C F
CC
Torres
J C N
JC
Castro
F M
FM
Croce
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000485:Allergens / Q000276:immunology*; D031021:Anacardium / Q000276:immunology*; D001249:Asthma / Q000276:immunology*; D002648:Child; D005260:Female; D006801:Humans; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000276:immunology; D010940:Plant Proteins / Q000032:analysis; D011058:Pollen / Q000276:immunology*
D000485:Allergens; D010936:Plant Extracts; D010940:Plant Proteins