The involvement of RNA in ribosome function.
The ribosome is a particle made of RNA and protein that is found in abundance in all cells that are actively making protein. It catalyses the messenger RNA-directed synthesis of proteins. Recent structural work has demonstrated a profound involvement of the ribosome's RNA component in all aspects of its function, supporting the hypothesis that proteins were added to the ribosome late in its evolution.
Moore
Peter B
PB
Department of Molecular Biophysics and Biochemistry, Yale University, PO Box 208107, New Haven, Connecticut 06520-8107, USA. peter.moore@yale.edu
Steitz
Thomas A
TA
D001665:Binding Sites; D019143:Evolution, Molecular; D008956:Models, Chemical; D008958:Models, Molecular; D012335:RNA, Ribosomal / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D012343:RNA, Transfer / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012270:Ribosomes / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*
D012335:RNA, Ribosomal; D012343:RNA, Transfer