Successful pregnancy in a woman with mut- methylmalonic acidaemia.
We report on a favourable pregnancy in a woman affected by mut- methylmalonic acidaemia. Under vitamin B12 and carnitine therapy she remained symptom-free throughout pregnancy, labour, delivery and the postpartum period and gave birth to a term, healthy female newborn. At follow-up, the child shows normal somatic and neurocognitive development.
Division of Metabolism, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
F
F
Deodato
C
C
Rizzo
S
S
Boenzi
F
F
Baiocco
G
G
Sabetta
C
C
Dionisi-Vici
D000328:Adult; D002331:Carnitine / Q000097:blood / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008661:Metabolism, Inborn Errors / Q000150:complications* / Q000188:drug therapy; D008764:Methylmalonic Acid / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D014805:Vitamin B 12 / Q000627:therapeutic use
D008764:Methylmalonic Acid; D014805:Vitamin B 12; D002331:Carnitine