Highly efficient use of NaOCl in the Ru-catalysed oxidation of aliphatic ethers to esters.
The selectivity of alpha-oxidation of ethers to esters via Ru-NaOCl can be dramatically improved by pH control, at high substrate to catalyst ratios using a stoichiometric amount of hypochlorite in biphasic media at room temperature.
Laboratory for Organic Chemistry and Catalysis, Delft University of Technology, Julianalaan 136 2628 BL, Delft, The Netherlands.
Luca
L
Gonsalvi
Isabel W C E
IW
Arends
Roger A
RA
Sheldon