The early diagnosis and prevention of gastrointestinal cancer: problems and promises.
Early detection and prevention of gastrointestinal cancer involves screening and surveillance. The efficacy of early detection tests should be subjected to well-designed studies. Clinical recommendation should be made after evaluation of new therapeutic approaches that will be based on our understanding of the molecular and cellular biology and the genetics of gastrointestinal premalignancy and cancer. Chemoprotection and alterations in diet and environment are areas that offer much promise and require clinical evaluation.
Katz
Julian
J
Division of Gastroenterology and Hepatology, Hospital of the Medical College of Pennsylvania, 3300 Henry Avenue, Mail Stop 913, Philadelphia, PA 19129, USA. jkatz@icdc.com
Reynolds
James C
JC
D000368:Aged; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000517:prevention & control*; D006801:Humans; D008403:Mass Screening; D008967:Molecular Biology; D011159:Population Surveillance; D017410:Practice Guidelines as Topic; D011230:Precancerous Conditions / Q000175:diagnosis / Q000235:genetics; D012307:Risk Factors