Chromosome Organization: Reaching out to Embrace New Models.
New information on the architecture of protein complexes involved in the dynamic organization of chromosomes challenges existing models of their structures and provides fresh insight into their mechanisms of action.
Wyman
Claire
C
Department of Cell Biology and Genetics, Erasmus Medical Center-Daniel den Hoed Cancer Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands. wyman@ch1.fgg.eur.nl
Kanaar
Roland
R
D017766:Acid Anhydride Hydrolases; D000251:Adenosine Triphosphatases / Q000378:metabolism; D018797:Cell Cycle Proteins / Q000378:metabolism; D011508:Chondroitin Sulfate Proteoglycans; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism; D015825:Chromosomes, Fungal / Q000737:chemistry* / Q000378:metabolism; D045643:DNA Repair Enzymes; D004261:DNA Replication; D004271:DNA, Fungal / Q000737:chemistry; D004268:DNA-Binding Proteins / Q000737:chemistry* / Q000378:metabolism; D019281:Dimerization; D005656:Fungal Proteins; D006801:Humans; D000076228:MRE11 Homologue Protein; D008958:Models, Molecular; D046912:Multiprotein Complexes; D009687:Nuclear Proteins / Q000737:chemistry* / Q000378:metabolism; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D000097722:Cohesins; D000098550:Structural Maintenance of Chromosome Protein 1
D017766:Acid Anhydride Hydrolases; D000251:Adenosine Triphosphatases; D018797:Cell Cycle Proteins; D011508:Chondroitin Sulfate Proteoglycans; D002868:Chromosomal Proteins, Non-Histone; D045643:DNA Repair Enzymes; D004271:DNA, Fungal; D004268:DNA-Binding Proteins; D005656:Fungal Proteins; D000076228:MRE11 Homologue Protein; D046912:Multiprotein Complexes; D009687:Nuclear Proteins; D000097722:Cohesins; D000098550:Structural Maintenance of Chromosome Protein 1; C121766:MRE11 protein, human; C492318:SMC3 protein, human; C108312:condensin complexes; C112158:RAD50 protein, human