Gene Expression Profiles of Human Fetal Nasopharyngeal Tissue.
To study differentially expressed genes in nasopharynx tissues of embryo during development, and to observe the gene changes, total RNAs were respectively extracted from the nasopharynx tissue which came from fetuses of 5, 6, 7, and 8 month, Probes were yielded by reverse transcription and were used to hybridize with the Atlas(TM) human cDNA expression arrays. The results showed that the genes expression profile were distinctly different and different expression levels were found in the same gene during development. Results indicated that gene expression pattern had a character of time-dependence, such as early growth response protein 1 and the cDNA expression array provided a powerful method for studying gene expression profile in a large range of genes.
He
Zhi-Wei
ZW
Key Laboratory of Carcinogenesis of Chinese Ministry of Public Health of Cancer Research Institute of Hunan Medical University, Changsha 410078, China. klcarcmh@public.cs.hn.cn
Xu
Liang-Guo
LG
Xie
Lu
L
Zhang
Ling
L
Lan
Ke
K
Ren
Cai-Ping
CP
Yao
Kai-Tai
KT