Dendritic polymer macromolecular carriers for drug delivery.
Dendrimers are synthetic, highly branched, mono-disperse macromolecules of nanometer dimensions. Started in the mid-1980s, the research investigations into the synthetic methodology, physical and chemical properties of these macromolecules are increasing exponentially with growing interest in this field. Potential applications for dendrimers are now forthcoming. Properties associated with these dendrimers such as uniform size, water solubility, modifiable surface functionality and available internal cavities make them attractive for biological and drug-delivery applications.
Center for Biologic Nanotechnology, Department of Internal Medicine, 9220C MSRB III, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, Michigan 48109-0648, USA.
Anil K
AK
Patri
István J
IJ
Majoros
James R
JR
Baker
D000818:Animals; D003257:Consumer Product Safety; D004337:Drug Carriers / Q000138:chemical synthesis* / Q000737:chemistry; D016503:Drug Delivery Systems / Q000379:methods; D006801:Humans; D046911:Macromolecular Substances
D004337:Drug Carriers; D046911:Macromolecular Substances