Evaluation of the analgesic activity of an ethanol extract of Miconia fallax.
A significant analgesic effect was observed after oral administration of an ethanol extract of Miconia fallax to mice, evaluated using chemical (writhing test) and thermal (hot plate test) stimuli. The extract showed a significant effect compared to control in both algesimetric models, suggesting that it was efficient in increasing the pain threshold.
Núcleo de Pesquisa em Ciências Exatas e Tecnológicas da Universidade de Franca, SP, Brazil.
M L
ML
Andrade e Silva
W R
WR
Cunha
C
C
Pedro
P
P
Aparecida Garcia
C
C
Martins
D000349:Africa; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D000431:Ethanol; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D051379:Mice; D010147:Pain Measurement / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D012997:Solvents
D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts; D012997:Solvents; D000431:Ethanol; D007213:Indomethacin