Amidation of silyl enol ethers and cholesteryl acetates with chiral ruthenium(II) schiff-base catalysts: catalytic and enantioselective studies.
Chiral ruthenium(II)-salen complexes [RuII(salen)(PPh3)2] catalyse asymmetric aziridination of alkenes with up to 83% ees, asymmetric amidation of silyl enol ethers with up to 97% ees, and allylic amidation of cholesteryl acetates with good regioselectivity.
Department of Chemistry and Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis.
Jiang-Lin
JL
Liang
Xiao-Qi
XQ
Yu
Chi-Ming
CM
Che
D000085:Acetates / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D002784:Cholesterol / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry*; D013237:Stereoisomerism
D000085:Acetates; D000577:Amides; D004987:Ethers; D012545:Schiff Bases; D012428:Ruthenium; D002784:Cholesterol