The design, synthesis and characterisation of channel-forming peptides.
Synthetic peptides designed using criteria derived from statistical analyses of beta-barrel membrane proteins form channels in synthetic membranes at very low peptide:lipid ratios.
Sanderson
John M
JM
Department of Chemistry, University Science Laboratories, South Road, Durham, UK DH1 3LE. j.m.sanderson@durham.ac.uk
Yazdani
Sarah
S
D000596:Amino Acids / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D008565:Membrane Proteins / Q000737:chemistry; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*
D000596:Amino Acids; D008565:Membrane Proteins; D010455:Peptides