The fluorine gauche effect. Langmuir isotherms report the relative conformational stability of (+/-)-erythro- and (+/-)-threo-9,10-difluorostearic acids.
(+/-)-Erythro- and (+/-)-threo-9,10-difluorostearic acids, which differ only by a stereogenic interconversion of a single C-F bond, have significantly different conformational stabilities.
Tavasli
Mustafa
M
School of Chemistry, University of St Andrews, Centre for Biomolecular Sciences, Haugh, North St Andrews, Fife, UK KY16 9ST.
O'Hagan
David
D
Pearson
Christopher
C
Petty
Michael C
MC