Direction selectivity in the retina.
The neuronal circuitry underlying the generation of direction selectivity in the retina has remained elusive for almost 40 years. Recent studies indicate that direction selectivity may be established within the radial dendrites of 'starburst' amacrine cells and that retinal ganglion cells may acquire their direction selectivity by the appropriate weighting of excitatory and inhibitory inputs from starburst dendrites pointing in different directions. If so, this would require unexpected complexity and subtlety in the synaptic connectivity of these CNS neurons.
Vision, Touch and Hearing Research Centre, School of Biomedical Sciences, The University of Queensland, Brisbane, 4072, Queensland, Australia. d.vaney@uq.edu.au
David I
DI
Vaney
W Rowland
WR
Taylor
D025042:Amacrine Cells / Q000033:anatomy & histology / Q000502:physiology; D000818:Animals; D009039:Motion Perception / Q000502:physiology*; D009433:Neural Inhibition; D012160:Retina / Q000033:anatomy & histology* / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000502:physiology; D009435:Synaptic Transmission