The emerging chemistry of blood product disinfection.
Given the importance and limitations of the blood supply worldwide, widely applicable procedures for the inactivation of pathogens (viruses, bacteria, protozoa etc.) in donated blood and blood products are now required. Conventional treatments such as ultraviolet irradiation cause damage to therapeutic components in the blood, so more targeted approaches are being sought. These include targeted chemotherapy, photochemotherapy and photodynamic antimicrobial chemotherapy (PACT).
Wainwright
Mark
M
University of Central Lancashire, Preston, UK PR1 2HE. Mwainwright@UCLan.ac.uk
D001688:Biological Products / Q000592:standards*; D001781:Blood Component Removal; D004203:Disinfection / Q000379:methods*; D011564:Furocoumarins; D006801:Humans; D011786:Quality Control
D001688:Biological Products; D011564:Furocoumarins