Use of preserved vascular homografts in liver transplantation: hepatic artery aneurysms and other complications.
Hepatic artery aneurysms/pseudoaneurysms (HAAs) are rare but serious complications after orthotopic liver transplantation (OLT). Revascularization should accompany aneurysmectomy if possible and is more feasible if the aneurysm presents late after transplantation. The optimal conduits for revascularization in this situation are not known. Two patients with hepatic artery aneurysms/pseudoaneurysms who had aneurysmectomy and revascularization with third-party cadaveric iliac arterial grafts 1 and 4 years after OLT are presented in detail, with an emphasis on the preservation method used for the grafts. Both livers were successfully revascularized with arterial grafts preserved for 21 and 26 days after procurement. Hepatic patency was documented in both 5 and 6 months after repair; graft function has remained normal 13 and 32 months after repair. Third-party vessels preserved for shorter periods have been used successfully in four other situations, including living-donor liver transplantation, and are briefly discussed. In conclusion, properly preserved vascular homografts are useful in LT for purposes other than initial vascular reconstruction. They also provide an excellent vascular conduit in recipients of livers from other (possibly living) donors.
Sellers
Marty T
MT
Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA. msellers@uab.edu
Haustein
Silke V
SV
McGuire
Brendan M
BM
Jones
Cathy
C
Bynon
J Stevenson
JS
Diethelm
Arnold G
AG
Eckhoff
Devin E
DE
D000328:Adult; D000783:Aneurysm / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D002102:Cadaver; D005260:Female; D006499:Hepatic Artery / Q000473:pathology / Q000601:surgery / Q000637:transplantation; D006801:Humans; D007083:Iliac Artery / Q000473:pathology; D007084:Iliac Vein / Q000473:pathology; D016031:Liver Transplantation; D008875:Middle Aged; D009926:Organ Preservation / Q000009:adverse effects; D014184:Transplantation, Homologous