[Mortality in a cohort of asbestos cement workers in Bari].
The study describes the mortality of 417 workers employed in a asbestos-cement plant, located in Bari, Puglia, Southern Italy. Follow up started on February 1st 1972. The vital status and cause of death were ascertained at 1995. The mortality experience of the Apulian population was used as comparison. Using 90% confidence limits (CLs), a significant increase in mortality was observed in our cohort from: all causes of death (SMR 118, CL 100-139), pneumoconiosis (SMR 14810, CL 10298-20683), all types of cancer (SMR 139, CL 105-181), lung (SMR 191, CL 126-277), pleural (SMR 1560 CL 431-4081) and peritoneum (SMR 1705, CL 303-5367) malignant neoplasms. In our cohort, the discrepancy between observed and expected mortality for lung and pleural cancer occurred 30 years after the first exposure, after 40 years for all neoplasms and peritoneum cancer. Under the Cox regression model, lung cancer SMR showed a curvilinear trend along time since first exposure, the peak being detected at 35 years. Finally, SMRs from our cohort were compared to a previously described cohort including workers from the same plant compensated for asbestosis by INAIL.
Unità di epidemiologia, Azienda unità sanitaria locale BA/1, Andria, Bari. coviello@mythnet.it
Vincenzo
V
Coviello
Monica
M
Carbonara
Lucia
L
Bisceglia
Carmela
C
Di Pierri
Giovanni M
GM
Ferri
Antonio
A
Lo Izzo
Antonio
A
Porro
Donato
D
Sivo
Giorgio
G
Assennato
D000328:Adult; D001194:Asbestos / Q000009:adverse effects*; D001195:Asbestosis / Q000401:mortality; D002423:Cause of Death; D015331:Cohort Studies; D003252:Construction Materials / Q000009:adverse effects*; D004066:Digestive System Diseases / Q000401:mortality; D019652:Extraction and Processing Industry / Q000706:statistics & numerical data; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy; D008171:Lung Diseases / Q000401:mortality; D008175:Lung Neoplasms / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000401:mortality*; D009784:Occupational Diseases / Q000401:mortality*; D010534:Peritoneal Neoplasms / Q000401:mortality; D010997:Pleural Neoplasms / Q000401:mortality; D011009:Pneumoconiosis / Q000401:mortality*; D016016:Proportional Hazards Models; D013997:Time Factors
D001194:Asbestos