Verruca vulgaris with CD30-positive lymphoid infiltrate: a case report.
Expression of CD30 has been reported in reactive lymphoid cells that accompany some cutaneous viral infections. It is interpreted as a marker of lymphocyte activation in response to the infecting virus. We report on a case of viral wart presenting with an inflammatory infiltrate with numerous CD30+ atypical lymphoid cells. These cells comprised approximately 10% of the reactive cell population and showed a T-helper phenotype. Infection by human papillomavirus should be included among the causes of cutaneous CD30+ reactive lymphoid infiltrates.
Department of Morphological Sciences and Legal Medicine, Section of Anatomic Pathology, University of Modena and Reggio Emilia, Italy. cesinaro.a@policlinico.mo.it
Anna M
AM
Cesinaro
Antonio
A
Maiorana
D015415:Biomarkers / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D017730:Ki-1 Antigen / Q000378:metabolism*; D008875:Middle Aged; D006377:T-Lymphocytes, Helper-Inducer / Q000378:metabolism / Q000473:pathology*; D014860:Warts / Q000378:metabolism / Q000473:pathology*
D015415:Biomarkers; D017730:Ki-1 Antigen