[Endoscopic, percutaneous and laparoscopic treatment for acute biliary pancreatitis].
OBJECTIVE
The aim of this study is to evaluate the results of acute gallstone pancreatitis treatment and to discuss indications in relation with the different forms of the disease.


METHODS
From january 1992 to june 2001, 137 patients have been treated for an acute gallstone pancreatitis. Diagnostic criteria were given by the history, clinical examination, biochemical and radiological findings. After exclusion of patients with a systemic disease, a group of 129 patients have been enrolled in a treatment regimen with an endoscopic retrograde cholangiopancreatography (ERCP) and eventual sphincterotomy, a percutaneous US-guided cholecystostomy (PC) when necessary and an elective laparoscopic cholecystectomy.


RESULTS
ERCP has been successfully performed in 121/129 patients. A PC has been performed in 5/8 patients of the failed endoscopic procedure and in 14 with acute cholecystitis. Retrograde and percutaneous cholangiographies showed main bile duct stones in 89 patients, a dilatation of the main bile duct without stones in 26 patients and a negative finding in 6 patients. An endoscopic sphincterotomy has been performed in 117 patients. A laparoscopic cholecystectomy has been performed in 118 patients. Mortality and morbidity rates were 1.6 and 10.3%, respectively.


CONCLUSIONS
ERCP and sphincterotomy seem to be indicated in all patients observed during the first 72 hours. Endoscopic treatment and percutaneous procedure make it possible to reduce at a very low rate the cases with an unfavourable course of the disease. A definitive treatment may then be performed by the way of a laparoscopic cholecystectomy.
I Divisione Clinicizzata di Chirurgia Generale, Université de Vérone, (Italie), Ospedale Civile Maggiore, Piazzale A Stefani 1, 37126 Vérone, Italie.
G
G
Borzellino
G
G
De Manzoni
G
G
Castaldini
R
R
Kind
G
G
Fracastoro
S
S
Tasselli
G
G
Zerman
C
C
Cordiano
D000208:Acute Disease; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects / Q000379:methods*; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects / Q000379:methods*; D002767:Cholecystostomy / Q000009:adverse effects / Q000379:methods*; D002769:Cholelithiasis / Q000150:complications*; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D009017:Morbidity; D010195:Pancreatitis / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000628:therapy*; D011446:Prospective Studies; D016717:Sphincterotomy, Endoscopic / Q000009:adverse effects / Q000379:methods*; D013105:Sphincterotomy, Transduodenal / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome