Labelling of [Leu5]-enkephalin with organometallic Mo complexes by solid-phase synthesis.
The neuropeptide leucine-enkephalin ([Leu5]-enkephalin) has been covalently labelled with the two organometallic Mo carbonyl complexes Mo(R-His)(allyl)(CO)2 (His = N delta,N,O-L-histidinate) and Mo(R-bpa)(CO)3 (bpa = bis(2-picolyl)a-mine) on the resin as the last step of a solid-phase synthesis scheme and in solution.
Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim/Ruhr, Germany.
Dave R
DR
van Staveren
Nils
N
Metzler-Nolte
D018360:Crystallography, X-Ray; D004348:Drug Labeling; D004563:Electrochemistry; D004743:Enkephalin, Leucine / Q000737:chemistry*; D008024:Ligands; D008956:Models, Chemical; D008982:Molybdenum / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D012996:Solutions; D013055:Spectrophotometry, Infrared
D008024:Ligands; D009942:Organometallic Compounds; D012996:Solutions; D004743:Enkephalin, Leucine; D008982:Molybdenum