[Adverse effects of multi-drug therapy in patients with tuberculosis and ways of their correction].
Thirty and seventy six patients with tuberculosis receiving multidrug therapy and 107 healthy persons were examined. There is a high rate (38.5%) of adverse responses to antibiotics, deteriorated baseline vitamin deficiency, PLO-AOA imbalance, poorer liver tests, preserved protein deficiency, and secondary immunodeficiency. The use of Trofosan, an enterosorbent-antioxidant complex, and MRT as pathogenetic drugs corrects the disorders found. With this, the incidence of adverse decreased on the average by 2 times and the efficiency of inpatient treatment increased.
Gel'berg
I S
IS
Vol'f
S B
SB
Vrublevskaia
N I
NI
Pigalkova
E N
EN
Krotkova
E N
EN
Shevchuk
D V
DV
Avlasenko
V S
VS
D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use*; D000995:Antitubercular Agents / Q000009:adverse effects*; D019587:Dietary Supplements; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000975:Antioxidants; D000995:Antitubercular Agents