[A clinical report of 12 case-times of living related liver transplantation].
OBJECTIVE
To evaluate and summarize the clinical application of living related liver transplantation (LRLT).


METHODS
A retrospective analysis was made in altogether 12 LRLT operations of living related liver transplantation performed in our department. The indication and timing, surgical complications, and nonsurgical issues including infection, rejection, advantages of LRLT in our series were reviewed.


RESULTS
All the 11 donors are uneventfully after operation; the first receptor was dead, and 10 receptors with Wilson's disease achieve long-term survival. The postoperative survival time till now is 58 w, 51 w, 48 w, 38 w, 37 w, 36 w, 22 w, 18 w, 10 w and 7 w, respectively. No rejection was detected in the recipients with Wilson's disease, whose liver function and cuprum oxidase level had returned to normal. In this 10 cases, 6 of them has returned or gone to school, 2 of them were discharged from hospital, 2 of them has been recovered smoothly in the hospital due to short time postoperatively. The primary complications after operation including blood vessel, biliary tract, lung and the infection of microbe or virus, were mainly involved in our series.


CONCLUSIONS
The process of operation was complicated; the operation technology was exigent and difficult with respect to the safety of the donors and receptors. LRLT has capacious clinical application for there are many unsurpassable advantages, such as plentiful resource and fine quality of graft liver, lower cost of LRLT.
Department of Liver Surgery, First Affiliated Hospital of NanJing Medical University, Liver Transplantation Center for Jiangsu Province, Nanjing 210029, China.
Xuehao
X
Wang
Feng
F
Zhang
Xiangcheng
X
Li
Jianmin
J
Qian
Lianbao
L
Kong
Jun
J
Huang
Zuhu
Z
Huang
Hao
H
Zhang
Guoqiang
G
Li
Feng
F
Cheng
Ke
K
Wang
Sen
S
Lu
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006527:Hepatolenticular Degeneration / Q000209:etiology*; D006801:Humans; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D011183:Postoperative Complications / Q000401:mortality / Q000503:physiopathology; D012189:Retrospective Studies