Perforated aneurysms of left side valves during active infective endocarditis complicating hypertrophic obstructive cardiomyopathy.
The most frequent site of vegetative lesion in patients with hypertrophic cardiomyopathy is anterior mitral leaflet, due to chronic endocardial trauma arising from systolic anterior motion. We describe three cases of serious infective endocarditis complicated lesions (vegetation, aneurysm and perforation) on aortic and mitral valves, in patients with obstructive hypertrophic cardiomyopathy. In particular, we observed how severe valvular damage and dysfunction, combined with particular hemodynamic conditions, are followed by adverse clinical outcome. We performed transthoracic echocardiogram and transoesophageal echocardiography studies to define morphologic and hemodynamic features of infection, deciding the proper therapy and we planned the echocardiographic follow-up.
Department of Cardiovascular and Respiratory Sciences, La Sapienza University, Rome, Italy. stefano.decastro@uniroma1.it
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S
de Castro
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R
Adorisio
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Pelliccia
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Papetti
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Fedele
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Pandian
D000328:Adult; D000785:Aneurysm, Infected / Q000000981:diagnostic imaging / Q000209:etiology*; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000209:etiology*; D001021:Aortic Valve / Q000000981:diagnostic imaging*; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D017809:Fatal Outcome; D005260:Female; D006322:Heart Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging*