Treatment of pseudobulbar laughter after gamma knife thalamotomy.
We describe a case of pathological laughter after gamma knife thalamotomy which resolved after treatment with sertraline. It is important to identify this potentially treatable complication of surgical therapy.
Emory University, Department of Neurology, Atlanta, Georgia, USA. msokun@dnamail.com
Michael S
MS
Okun
Kenneth M
KM
Heilman
Jerrold L
JL
Vitek
D006801:Humans; D007845:Laughter; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000601:surgery*; D020828:Pseudobulbar Palsy / Q000188:drug therapy / Q000209:etiology*; D016634:Radiosurgery / Q000009:adverse effects*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D020280:Sertraline / Q000627:therapeutic use; D013787:Thalamic Nuclei / Q000601:surgery*
D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline