The omp-1 major outer membrane multigene family of Ehrlichia chaffeensis is differentially expressed in canine and tick hosts.
Sixteen of 22 omp-1 paralogs encoding 28-kDa-range immunodominant outer membrane proteins of Ehrlichia chaffeensis were transcribed in blood monocytes of dogs throughout a 56-day infection period. Only one paralog was transcribed by E. chaffeensis in three developmental stages of Amblyomma americanum ticks before or after E. chaffeensis transmission to naïve dogs.
Unver
Ahmet
A
Department of Veterinary Biosciences, The Ohio State University, Columbus 43210-1093, USA.
Rikihisa
Yasuko
Y
Stich
Roger W
RW
Ohashi
Norio
N
Felek
Suleyman
S
D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D004195:Disease Models, Animal; D004285:Dogs; D018469:Ehrlichia chaffeensis / Q000235:genetics*; D016873:Ehrlichiosis / Q000382:microbiology*; D015870:Gene Expression; D005798:Genes, Bacterial; D008297:Male; D005810:Multigene Family; D012336:RNA, Ribosomal, 16S; D013987:Ticks / Q000382:microbiology
D001425:Bacterial Outer Membrane Proteins; D012336:RNA, Ribosomal, 16S