First Ritter-type reaction of alkylbenzenes using N-hydroxyphthalimide as a key catalyst.
The first Ritter-type reaction of alkylbenzenes with nitriles has been successfully achieved by the use of N-hydroxyphthalimide (NHPI) as a key catalyst. Thus, treatment of ethylbenzene with ammonium hexanitratocerate(IV) (CAN) in the presence of a catalytic amount of NHPI in EtCN under argon produced the corresponding amide in good selectivity.
Department of Applied Chemistry, Faculty of Engineering, Kansai University, Suita, Osaka 564-8680, Japan.
Satoshi
S
Sakaguchi
Tomotaka
T
Hirabayashi
Yasutaka
Y
Ishii