Imaging of in vitro chicken leg using time-resolved near-infrared optical tomography.
Near-infrared optical imaging gains much attention because of its noninvasiveness and deep penetration depths into tissue. Here, we report near-infrared optical tomographic imaging of an in vitro chicken leg from time-resolved measurements. The in vitro chicken leg, dipped in a cylindrical container filled with diluted Intralipid-10% solution, was imaged with a multichannel time-resolved imaging system. A two-dimensional reconstruction algorithm based on a modified generalized pulse spectrum technique has been developed to reconstruct the images of both the absorption and reduced scattering coefficients simultaneously and quickly. The results demonstrate that a simultaneous reconstruction of absorption and reduced scattering coefficients from time-resolved measurement has a potential to reveal the changes in the optical properties associated with not only the physiological information but also the anatomical structure of the organ.
Zhao
Huijuan
H
National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan.
Gao
Feng
F
Tanikawa
Yukari
Y
Onodera
Yoichi
Y
Ohmi
Masato
M
Haruna
Masamitsu
M
Yamada
Yukio
Y
D000465:Algorithms; D000818:Animals; D002645:Chickens; D005121:Extremities / Q000473:pathology*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008962:Models, Theoretical; D015203:Reproducibility of Results; D013997:Time Factors; D014054:Tomography / Q000379:methods*