Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis.
Varga
John
J
Section of Rheumatology, University of Illinois at Chicago, College of Medicine, 60607, USA. jvarga@uic.edu
D004268:DNA-Binding Proteins / Q000502:physiology*; D005355:Fibrosis / Q000473:pathology*; D006801:Humans; D012595:Scleroderma, Systemic / Q000378:metabolism / Q000473:pathology*; D015398:Signal Transduction / Q000502:physiology; D051785:Smad Proteins; D015534:Trans-Activators / Q000502:physiology*; D016212:Transforming Growth Factor beta / Q000502:physiology*
D004268:DNA-Binding Proteins; D051785:Smad Proteins; D015534:Trans-Activators; D016212:Transforming Growth Factor beta