Recurrent urticaria as a rare manifestation of familial Mediterranean fever.
Familial Mediterranean fever (FMF) is a genetic disorder characterized by acute episodes of fever with some combination of severe abdominal pain, pleurisy, arthritis, and skin rash. The case of a patient with recurrent urticaria referred for study of drug allergy is presented. After allergy had been ruled out, the urticaria was attributed to previously undiagnosed symptoms of an underlying systemic disease: FME. Urticaria is the least frequent cutaneous manifestation of this disease, and genetic analysis was required to confirm the diagnosis.
Alonso
R
R
Allergy and Clinical Immunology Unit, Institut Universitari Dexeus, Barcelona, Spain.
Cisteró-Bahima
A
A
Enrique
E
E
San Miguel-Moncín
M M
MM
D000328:Adult; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D012008:Recurrence; D014581:Urticaria / Q000150:complications* / Q000503:physiopathology