Pest-managing efficacy of trans-asarone isolated from Daucus carota L. seeds.
The bioactive hexane extract of Daucus carota seed yielded 2,4,5-trimethoxybenzaldehyde (1), oleic acid (2), trans-asarone (3), and geraniol (4). Compounds 1-4 were evaluated for their mosquitocidal, nematicidal, antifeedant, and antimicrobial activities. Only trans-asarone was active in the assays performed, causing 100% mortality to fourth-instar mosquito larvae, Aedes aegyptii, at 200 microg mL(-1) and the nematodes Caenorhabditis elegans and Panagrellus redivivus at 100 microg mL(-1). In feeding trials, trans-asarone also caused significant weight reductions of the caterpillars Helicovarpa zea, Heliothis virescens, and Manduca sexta when incorporated into artificial diet at a concentration of 100 microg mL(-1). Also, it exhibited slight activity at 100 microg mL(-1) against the yeasts Candida albicans, Candida parapsilasis, and Candida kruseii.
Momin
Rafikali A
RA
Bioactive Natural Products and Phytoceuticals, Department of Horticulture and National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA.
Nair
Muraleeddharan G
MG
D000330:Aedes; D000081248:Allylbenzene Derivatives; D000818:Animals; D000840:Anisoles / Q000302:isolation & purification; D000969:Antinematodal Agents; D017173:Caenorhabditis elegans; D018552:Daucus carota / Q000737:chemistry*; D007306:Insecticides; D007814:Larva; D018402:Manduca; D009036:Moths; D010575:Pesticides; D010936:Plant Extracts / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*
D000081248:Allylbenzene Derivatives; D000840:Anisoles; D000969:Antinematodal Agents; D007306:Insecticides; D010575:Pesticides; D010936:Plant Extracts; C012195:asarone