[Treatment adherence amongst HIV-infected patients in Rotterdam: poorer prognosis independent of nationality in heterosexual infected patients, intravenous drug users, Negroid and Latin-American patients].
OBJECTIVE
To assess adherence to antiretroviral therapy (ART) in Dutch and non-Dutch HIV-infected patients.


METHODS
Observational, cross-sectional study.


METHODS
Consecutive HIV-infected patients taking ART and visiting the internal medicine outpatients' clinic at the Rotterdam Dijkzigt University Hospital between 1 February until 30 April 2001 were interviewed by a multilingual interviewer using a standard questionnaire. Classification of adherence was based on the interview data. Multivariate analysis was used to determine independent predictors of adherence. Nationality was defined as 'Dutch' if the person was born in the Netherlands, and otherwise as 'non-Dutch'.


RESULTS
The 203 patients included in this study comprised 131 men and 69 women with an average age of 42 years. There were no data available on treatment adherence for 3 of the patients. Of the 81 Dutch patients, 60 (74%) adhered to the treatment compared with 68 (57%) of the 119 non-Dutch patients. However, after correction for sex, risk group, race and duration of treatment, there was no difference in treatment adherence between these two groups (OR: 0.6; 95% CI: 0.2-1.9). Failure to adhere to treatment was seen most frequently in the 109 heterosexually infected patients (OR: 2.6; 0.98-6.7), the 22 intravenous drug users (OR: 3.3; 1.04-10.1), as well as in the group of Negroid patients (OR: 3.5; 1.1-11.3) and Latin-American patients (OR: 8.5; 1.7-42.7).
Academisch Ziekenhuis Rotterdam-Dijkzigt, afd. Inwendige Geneeskunde, Dr. Molewaterplein 40, 3015 GD Rotterdam.
E L M
EL
Kooiman
J P
JP
Dieleman
I C
IC
Gyssens
P T
PT
Nieuwkerk
S
S
de Marie
M E
ME
van der Ende
D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009426:Netherlands; D010349:Patient Compliance / Q000208:ethnology; D011379:Prognosis; D011795:Surveys and Questionnaires