Inducible Expression of bcl-2 Antisense RNA Promotes Apoptosis of Human Gastric Cancer Cell Line.
A lot of molecular biological techniques was used to observe the effect of bcl-2 antisence RNA on human gastric cancer cell line SGC7901 and to detect the inducibility and promotion of MT-II promoter. The results showed that MT-II promoter could be activated by the induction with 160 &mgr;mol/L Zn(2+) and the expression of Bcl-2 plays an important role in apoptosis of SGC7901 cells.
Zhang
Jie
J
Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China. jiezhang@163.net
Peng
Wei-Dan
WD
Hui
Hong-Xiang
HX
Jin
Ming
M
Wang
Duo-Ning
DN
Wang
Cheng-Ji
CJ
Qian
Huan-Wen
HW