Investigations into the Pd-catalysed cross-coupling of phenylacetylene with aryl chlorides: simple one-pot procedure and the effect of ZnCl2 co-catalysis.
[PdCl(C6H3(OPPri2)2-2,6)] 1 catalyses the coupling of electron-rich, electron-neutral and electron-deficient aryl chlorides with phenylacetylene in the presence of ZnCl2 as cocatalyst to give the products in modest to excellent yields.
Department of Chemistry, University of Hawaii, Honolulu, Hawaii 96822, USA.
Michael R
MR
Eberhard
Zhaohui
Z
Wang
Craig M
CM
Jensen
D000114:Acetylene / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism*; D002384:Catalysis; D002712:Chlorides / Q000494:pharmacology*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis*; D006843:Hydrocarbons, Chlorinated / Q000138:chemical synthesis*; D010165:Palladium / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D017967:Zinc Compounds / Q000494:pharmacology*
D002712:Chlorides; D006841:Hydrocarbons, Aromatic; D006843:Hydrocarbons, Chlorinated; D017967:Zinc Compounds; C044736:phenylacetylene; D010165:Palladium; C016837:zinc chloride; D000114:Acetylene