The fixation of linear versus loop-type peptidic structures by metal coordination: the coordination chemistry of Val-Val- and Val-Val-Val-bridged dicatechol ligands.
The Val-Val-bridged dicatechol ligand L1-H4 forms triplybridged dinuclear complexes with titanium(IV) ions, while the more flexible Val-Val-Val derivative L2-H4 leads to mixtures of complexes containing species with a cyclic arrangement of the ligand; with [cis-MoO2]2+ on the other hand, a well-defined macrocycle [(L2)MoO2]2- is formed which possesses a loop-type structure in the peptidic part of the ligand.
Institut für Organische Chemie, Universität Karlsruhe, Richard-Willstätter-Allee, D-76131 Karlsruhe, Germany. albrecht@ochhades.chemie.uni-karlsruhe.de
Markus
M
Albrecht
Oliver
O
Spiess
Matthias
M
Schneider
Patrick
P
Weis
D015374:Biosensing Techniques / Q000379:methods; D002396:Catechols / Q000737:chemistry; D008024:Ligands; D019216:Metals, Heavy / Q000737:chemistry* / Q000494:pharmacology; D015394:Molecular Structure; D008982:Molybdenum / Q000737:chemistry; D009842:Oligopeptides / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry; D017433:Protein Structure, Secondary / Q000187:drug effects; D014025:Titanium / Q000737:chemistry; D014633:Valine / Q000737:chemistry
D002396:Catechols; D008024:Ligands; D019216:Metals, Heavy; D009842:Oligopeptides; D009942:Organometallic Compounds; D008982:Molybdenum; D014025:Titanium; D014633:Valine; C034221:catechol