Reproducibility of blood pressure variation in older ambulatory and bedridden subjects.
OBJECTIVE
We investigated the influence of ambulation on the reproducibility of circadian blood pressure variation in older nursing home residents.


METHODS
Ambulatory blood pressure monitoring was performed twice in 37 older nursing home residents.


METHODS
Nursing home in Japan.


METHODS
Subjects included 18 ambulatory nursing home residents who had no limitation on physical activity and 19 bedridden residents who did not participate in physical activity.


METHODS
Twenty-four-hour, daytime, and nighttime blood pressure levels and their variability.


RESULTS
The 24-hour and daytime variability of systolic blood pressure (SBP) was significantly greater in ambulatory than in bedridden subjects, whereas nighttime variability was similar. Significant correlations in SBP averaged for the whole day, daytime, and nighttime were observed between the two examinations in ambulatory (r =.80-.83) and bedridden (r =.83-.91) subjects, but the variabilities of SBP for the whole day and during the daytime of the first measurement were correlated with those of the second measurement in bedridden (r =.67 and r =.47, respectively) but not in ambulatory (r =.39 and r =.28, respectively) subjects. Significant correlations were found between the nocturnal SBP changes at two occasions in both ambulatory (r =.50) and bedridden (r =.51) subjects, but the dipper versus nondipper profiles, defined as reduction in SBP of greater than 10% versus not, showed low reproducibility in ambulatory subjects; five ambulatory (28%) and one bedridden (5%) subjects showed divergent profiles between the two examinations.


CONCLUSIONS
The reproducibility of blood pressure variation in nursing home residents is influenced by ambulation.
Tsuchihashi
Takuya
T
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Maidashi 3-1-1, Higashi-ku, Fukuoka 812-8582, Japan. tuti@intmed2.med.kyushu-u.ac.jp
Kawakami
Yasunobu
Y
Imamura
Tsuyoshi
T
Abe
Isao
I
D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006801:Humans; D007103:Immobilization / Q000502:physiology*; D008297:Male; D015203:Reproducibility of Results; D016138:Walking / Q000502:physiology*