Indocyanine green angiographic findings in systemic lupus erythematosus choroidopathy.
OBJECTIVE
To report two patients affected with systemic lupus erythematosus choroidopathy studied with combined fluorescein angiography and indocyanine green angiography. In particular, the presence of choroidal abnormalities at indocyanine green angiography, which could not be detected by fluorescein angiography, was studied.


METHODS
Observational case reports.


METHODS
Retrospective review of the clinical and photographic records of two patients with systemic lupus erythematosus in whom choroidopathy developed.


RESULTS
Four findings were unveiled by indocyanine green angiography: focal, transient hypofluorescent areas in the very early phase; fuzziness of large choroidal vessels with late diffuse zonal choroidal hyperfluorescence; poorly-defined areas of choroidal hypofluorescence visible up to the late phase; and focal cluster of pinpoint spots of choroidal hyperfluorescence visible from the intermediate to late phase.


CONCLUSIONS
Indocyanine green angiography can provide information that is not detectable by clinical or fluorescein angiographic examination in patients with systemic lupus erythematosus choroidopathy. This information may prove useful in better understanding the pathogenesis of systemic lupus erythematosus choroidopathy.
Institute of Ophthalmology, University of Rome "La Sapienza", Rome, Italy. magda.gharbiya@tiscalinet.it
Magda
M
Gharbiya
Francesco
F
Bozzoni-Pantaleoni
Federico
F
Augello
Corrado
C
Balacco-Gabrieli
D000328:Adult; D002829:Choroid / Q000098:blood supply; D015862:Choroid Diseases / Q000175:diagnosis*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D007208:Indocyanine Green; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis*; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012164:Retinal Diseases / Q000175:diagnosis; D012189:Retrospective Studies
D004396:Coloring Agents; D007208:Indocyanine Green