Successful pregnancy in a patient with a 46,XY karyotype.
OBJECTIVE
To report a case of successful pregnancy in a patient with 46,XY karyotype with primary ovarian failure.


METHODS
Case report.


METHODS
Fertility Research Center, G.G. Hospital, Chennai, Tamil Nadu, India.


METHODS
A 27-year-old woman with hypoplastic uterus, normal fallopian tubes on both sides, and gonadal dysgenesis.


METHODS
Chromosomal analysis, diagnostic laparoscopy, donor oocyte program, gamete intrafallopian transfer, and gonadectomy.


METHODS
Response to hormone replacement therapy and the probability of achieving a pregnancy by a tubal procedure.


RESULTS
Treatment was successful, and the patient delivered a live baby.


CONCLUSIONS
A hypoplastic uterus of patients with the 46,XY karyotype can be stimulated by the use of cyclical steroid therapy to accommodate pregnancy and facilitate tubal procedures in patients with normal fallopian tubes.
Fertility Research Center, G.G. Hospital, Tamil Nadu, India. kamala@giasmd01.vsnl.net.in
Kamala
K
Selvaraj
Vijaya
V
Ganesh
Priya
P
Selvaraj
D000328:Adult; D004966:Estrogens, Conjugated (USP) / Q000627:therapeutic use; D005260:Female; D015181:Gamete Intrafallopian Transfer; D006061:Gonadal Dysgenesis, 46,XY / Q000150:complications*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome
D004966:Estrogens, Conjugated (USP)