Subsystem organ function during coronary surgery.
Conventional coronary artery bypass grafting (CABG) carries a mortality rate of 1% to 2% in elective patients. However, despite advances in perfusion, anaesthetic, and surgical techniques cardiopulmonary bypass (CPB) is still associated with subsystem dysfunction. Off-pump coronary artery bypass grafting (OPCAB) has recently gained popularity as a potentially more physiological method to maintain the functional integrity of major organ systems. The review of observational reports, case-matched studies and prospective randomized trials seems to suggest that OPCAB surgery reduces postoperative subsystem organ dysfunction when compared with conventional coronary revascularisation.
Bristol Heart Institute, University of Bristol, UK.
Raimondo
R
Ascione
Sharif
S
Al-Ruzzeh
Khalid
K
Amer
Gianni D
GD
Angelini
D000818:Animals; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000379:methods / Q000592:standards; D006801:Humans; D007431:Intraoperative Complications; D009204:Myocardial Revascularization / Q000009:adverse effects; D010829:Physiological Phenomena; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*