The detection and identification of 42,43,44,45,46,47,55-heptanor-41-oxoyessotoxin, a new marine toxin from adriatic shellfish, by liquid chromatography-mass spectrometry.
The diarrhetic shellfish toxin composition in the digestive glands of mussels collected in June 2001 from the Northern Adriatic sea was investigated by high-performance liquid chromatography coupled with electrospray ion trap mass spectrometry. Along with known yessotoxins (1, 3-6), identified by comparison of their retention times and mass spectra with those of appropriate standards, a new marine toxin, 42,43,44,45,46,47,55-heptanor-41-oxoyessotoxin, 7, was detected. MS/MS experiments were used to gain structural information. 7 represents a new addition to the class of yessotoxins.
Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, via D. Montesano 49, 80131, Napoli, Italy. ciminiel@unina.it
Patrizia
P
Ciminiello
Carmela
C
Dell'Aversano
Ernesto
E
Fattorusso
Martino
M
Forino
Silvana
S
Magno
Roberto
R
Poletti
D000818:Animals; D049872:Bivalvia; D002853:Chromatography, Liquid; D004988:Ethers, Cyclic / Q000737:chemistry / Q000302:isolation & purification; D008978:Mollusk Venoms / Q000737:chemistry / Q000302:isolation & purification*; D009792:Oceans and Seas; D021241:Spectrometry, Mass, Electrospray Ionization
C432526:42,43,44,45,46,47,55-heptanor-41-oxohomoyessotoxin; D004988:Ethers, Cyclic; D008978:Mollusk Venoms