Kaposi's sarcoma biology.
Cancer remains a major burden for HIV-infected individuals. The majority of cancers associated with HIV infection are driven by oncogenic viruses like Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus and human papillomavirus. Kaposi's sarcoma is a tumour of endothelium and is the most common malignancy in HIV infected individuals. AIDS-related cancers are providing critical insight into cancer immunity and viral oncogenesis.
Wolfson Institute for Biomedical Research, University College London, United Kingdom. c.boshoff@ucl.ac.uk
Chris
C
Boshoff
D000998:Antiviral Agents / Q000494:pharmacology; D005871:Castleman Disease / Q000150:complications; D019288:Herpesvirus 8, Human / Q000378:metabolism; D006801:Humans; D008223:Lymphoma / Q000821:virology; D012514:Sarcoma, Kaposi / Q000150:complications* / Q000175:diagnosis* / Q000378:metabolism
D000998:Antiviral Agents