Idiopathic calciphylaxis.
A 68-year-old woman presented with a painful necrotic ulcer on her right calf and necrotic breakdown of a left below-knee amputation stump as a result of calciphylaxis. No cause could be identified and corrected. Treatment comprised wound care, substituting low molecular weight heparin for warfarin, hyperbaric oxygenation and etidronate disodium, none of which were helpful and major limb amputations were considered the best option for this patient.
Department of Vascular Surgery, The Alfred Hospital, Commercial Road, Prahran, Victoria, Australia.
Jeremy P
JP
Banky
John P
JP
Dowling
Campbell
C
Miles
D000368:Aged; D000672:Amputation Stumps / Q000503:physiopathology; D001707:Biopsy, Needle; D002115:Calciphylaxis / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods; D007677:Kidney Function Tests; D007871:Leg Ulcer / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D018570:Risk Assessment; D016896:Treatment Outcome; D014945:Wound Healing
D005343:Fibrinolytic Agents