Calcified metastatic brain tumor--two case reports.
A 29-year-old man and a 46-year-old woman presented with calcified brain metastasis from pulmonary adenocarcinoma. Both patients had a relatively benign clinical course and prolonged survival after total removal of the tumors. The male patient was still alive 2 years 3 months after surgical resection of the metastatic and primary tumors. The female patient had had brain metastasis 8 years after surgical resection of lung cancer, and survived for 3 years 3 months after removal of the brain metastasis. The MIB-1 indexes of the two cases were relatively low compared with other cases of brain metastases. Calcification and low MIB-1 index may indicate longer survival in patients with metastatic tumors if the primary tumor is controlled.
Department of Neurosurgery, Yamaguchi University School of Medicine, Ube, Yamaguchi, Japan.
Yoshinori
Y
Ohmoto
Takafumi
T
Nishizaki
Koji
K
Kajiwara
Sadahiro
S
Nomura
Hideki
H
Kameda
Michiyasu
M
Suzuki
D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D000328:Adult; D034961:Antigens, Nuclear; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D002114:Calcinosis / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005625:Frontal Lobe / Q000473:pathology*; D006801:Humans; D019394:Ki-67 Antigen; D008175:Lung Neoplasms / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis; D009687:Nuclear Proteins / Q000032:analysis; D011379:Prognosis; D014057:Tomography, X-Ray Computed
D034961:Antigens, Nuclear; D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D009363:Neoplasm Proteins; D009687:Nuclear Proteins