Use of lufenuron as a treatment for fungal endometritis in four mares.
Lufenuron, a benzoylphenyl urea derivative, was evaluated as a treatment for endometrial fungal infections in 4 mares. Intrauterine lavage was performed with lufenuron suspended in sterile saline (0.9% NaCl) solution. Cytologic evaluation and fungal culture of the endometrium, as well as subsequent reproductive performance, were used to monitor efficacy of this treatment. Fungal endometritis in mares is associated with infertility. Treatment is often ineffective and costly, and recurrence following treatment is not uncommon. Intrauterine infusions of lufenuron were effective in eliminating fungal endometritis in the 4 mares of this report.
Department of Large Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA.
Milan B
MB
Hess
Nikola A
NA
Parker
Beverly J
BJ
Purswell
John D
JD
Dascanio
D000818:Animals; D001228:Aspergillosis / Q000188:drug therapy / Q000662:veterinary; D001549:Benzamides / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy / Q000662:veterinary; D004716:Endometritis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D005298:Fertility; D006734:Horse Diseases / Q000188:drug therapy* / Q000382:microbiology; D006736:Horses; D007306:Insecticides / Q000627:therapeutic use*; D012008:Recurrence; D016896:Treatment Outcome; D014599:Uterus / Q000166:cytology / Q000473:pathology; D005466:Fluorocarbons
D001549:Benzamides; D007306:Insecticides; C070364:fluphenacur; D005466:Fluorocarbons