Coronary artery stenting in diabetes mellitus--unfavourable clinical outcome due to increased rate of myocardial ischemia and percutaneous interventions.
Diabetes mellitus is one of the major risk factors for cardiovascular diseases. The aim of this study was to analyze if diabetic patients, compared to nondiabetic patients, have a worse angiographic and clinical success rate and a reduced clinical and angiographic outcome at three-months follow-up after coronary artery stenting according to postprocedural complications, recurrent angina, myocardial ischemia, restenosis and revascularization. A total of 307 unselected patients with coronary artery disease and myocardial ischemia who underwent intracoronary stenting were included in this study. Diabetes was present in 49 patients. Morphological criteria, angiographic results and clinical in-hospital outcome did not differ significantly between both groups. At follow-up diabetics presented significantly more often recurrent angina and myocardial ischemia. The rate of restenosis and target lesion revascularization was not different. Among diabetics, the rate of percutaneous coronary interventions because of different lesions was significantly increased. Diabetes does not reduce the angiographic result initially and at follow-up after coronary artery stenting. Diabetes mellitus limits the clinical outcome because of recurrent angina, myocardial ischemia and the need of coronary interventions.
Department of Cardiology and Angiology, Berufsgenossenschaftliche Kliniken Bergmannsheil, University of Bochum, Bürkle-de-la-Camp-Platz 1, D-44789 Bochum, Germany. alfried.germing@ruhr-uni-bochum.de
A
A
Germing
S
S
von Dryander
W
W
Bojara
T
T
Lawo
P
P
Grewe
A
A
Machraoui
B
B
Lemke
D000368:Aged; D000787:Angina Pectoris / Q000453:epidemiology; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000453:epidemiology; D023921:Coronary Stenosis / Q000453:epidemiology* / Q000628:therapy*; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000453:epidemiology* / Q000628:therapy*; D012008:Recurrence; D012307:Risk Factors; D015607:Stents; D017211:Treatment Failure