Anticholinergic poisoning from a large dose of Scopolia extract.
Scopolia extract (SE) contains hyoscyamine and scopolamine, which are both anticholinergic. It is usually used as a patent medicine to treat gastrointestinal disorders, to relieve spasmotic discomfort, or to decrease the secretion of gastric acid. Poisoning by SE presents similar symptoms and signs as other types of anticholinergic poisoning. We report a case of severe anticholinergic poisoning after accidentally drinking 8 ml of SE. The patient presented with acute delirium and was successfully treated with physostigmine.
Cheng
Sheng-Wen
SW
Department of Emergency Medicine, Taichung Veterans General Hospital, Chung-Sun Medical and Dental College, Taiwan.
Hu
Wei-Hsiung
WH
Hung
Dong-Zong
DZ
Yang
Dar-Yu
DY
D000284:Administration, Oral; D018680:Cholinergic Antagonists / Q000008:administration & dosage / Q000506:poisoning*; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003693:Delirium / Q000139:chemically induced*; D062787:Drug Overdose; D006801:Humans; D008297:Male; D008875:Middle Aged; D010830:Physostigmine / Q000627:therapeutic use; D010936:Plant Extracts / Q000008:administration & dosage / Q000506:poisoning*; D032603:Scopolia / Q000737:chemistry*
D018680:Cholinergic Antagonists; D002800:Cholinesterase Inhibitors; D010936:Plant Extracts; D010830:Physostigmine