Cryptophanols, new versatile compounds for the synthesis of functionalized cryptophanes and polycryptophanes.
After deprotection with a palladium catalyst, mono-allylated cryptophane-A (1, 2) and cryptophane-E (3) gave the new cryptophanols 4, 5 and 6, respectively, which are important key compounds for the preparation of monofunctionalized cryptophanes as well as for the design of large supramolecular hosts such as the bis-cryptophanes 7 and 8.
Darzac
Magali
M
Ecole Normale Supérieure de Lyon (UMR CNRS 5532), 46 Allée d'Italie, F-69364 Lyon, France.
Brotin
Thierry
T
Bouchu
Denis
D
Dutasta
Jean-Pierre
JP