Lymphoepithelial carcinoma of the larynx.
Lymphoepithelial carcinoma is a very rare tumour of the larynx, with an exhaustive review of the literature having disclosed only 33 documented cases. The relationship between lymphoepithelial carcinoma of the larynx and Epstein-Barr virus is still controversial. We describe one new case of this tumour involving the supraglottis. The patient was treated with supraglottic laryngectomy and left modified neck dissection. Three years and 4 months later, the right side of the neck was found positive for metastatic disease and a right modified neck dissection was performed. No evidence of disease was exhibited 4 years after the diagnosis of metastatic disease. The diagnostic problems and therapy associated with this rare tumour are discussed.
Marioni
Gino
G
Department of Otolaryngology-Head and Neck Surgery, University of Padua, Italy. g_marioni@virgilio.it
Mariuzzi
Laura
L
Gaio
Elena
E
Portaleone
Sara
S
Pertoldi
Barbara
B
Staffieri
Alberto
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000912:Antibodies, Neoplasm / Q000276:immunology; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D007822:Laryngeal Neoplasms / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy / Q000379:methods; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction
D000912:Antibodies, Neoplasm