Identification of a new HLA-B null allele, B*1817 N, in a family.
We describe a new HLA-B null allele found in a daughter and her mother. This null allele was due to a mutation at position 41 of exon 1 which resulted in a premature stop codon. This new null allele was officially named HLA-B*1817N*.
denHollander
N
N
Regional Histocompatibility Laboratory, UHN, Toronto, ON, Canada. neal.denhollander@uhn.on.ca
Li
J
J
van Oosterwijk
A
A
Ng
C-M
CM
Singal
D P
DP
D000483:Alleles; D001483:Base Sequence; D018389:Codon, Nonsense / Q000235:genetics*; D005192:Family Health; D005260:Female; D015235:HLA-B Antigens / Q000235:genetics*; D059911:HLA-B18 Antigen; D006801:Humans; D008969:Molecular Sequence Data
D018389:Codon, Nonsense; D015235:HLA-B Antigens; C471443:HLA-B*18:17N antigen; D059911:HLA-B18 Antigen