Statistical analysis for estimating heterogeneity of the Korean population in DNA typing using STR loci.
The coancestry coefficients for the Korean population are estimated by using 3 statistical methods for 17 loci (D3S1358, D21S11, D13S317, D18S51, D7S820, D8S1179, D5S818, FGA, VWA, F13A1, FES/FPS, THO1, TPOX, CSF1PO, D12S391, GABA and ACTBP2). The subpopulations were considered by last name and home origin, respectively. Our results show that the values for the coancestry coefficient for the Korean population are too large to ignore although they do not show substantial heterogeneity. These estimated values are also applied to simulated forensic cases.
Lee
J W
JW
Department of Statistics, Korea University, 5-1, Anam-Dong, Sungbuk-Gu, Seoul 136-701, Korea. jael@mail.korea.ac.kr
Lee
Hye-Seung
HS
Hwang
Juck-Joon
JJ
D005554:Forensic Medicine / Q000379:methods; D005787:Gene Frequency; D018740:Genetic Heterogeneity; D005819:Genetic Markers; D006801:Humans; D007723:Korea; D017422:Sequence Analysis, DNA; D020080:Tandem Repeat Sequences / Q000235:genetics*
D005819:Genetic Markers