Study of alpha-crustacyanin utilizing halogenated canthaxanthins.
[structure: see text] The preparations and spectroscopic characteristics of five all-trans halogenated canthaxanthins are described in this letter. The air/light-sensitive halogenated canthaxanthins were used to study alpha-crustacyanin, a blue astaxanthin-protein complex, which is isolated from the carapace of the lobster. Steric and electronegative effects of the halogen substituents on the noncovalent interaction between astaxanthin and the protein in alpha-crustacyanin were observed.
Liu
Jin
J
Department of Chemistry, Murray State University, Murray, Kentucky 42071, USA. jin.liu@murraystate.edu
Shelton
Nicole L
NL
Liu
Robert S H
RS
D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis; D016644:Canthaxanthin / Q000138:chemical synthesis* / Q000737:chemistry; D002352:Carrier Proteins; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis; D008121:Nephropidae / Q000737:chemistry; D019906:Nuclear Magnetic Resonance, Biomolecular; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry*; D013057:Spectrum Analysis; D013329:Structure-Activity Relationship
D000975:Antioxidants; D002352:Carrier Proteins; D006846:Hydrocarbons, Halogenated; D011506:Proteins; C018494:crustacyanins; D016644:Canthaxanthin