[Respiratory and renal functions and blood electrolytic composition in patients with pulmonary tuberculosis in the treatment of heart failure].
The authors studied respiratory and renal functions and blood electrolytic composition in 94 patients with pulmonary tuberculosis in the treatment of heart failure with angiotensin-converting enzyme inhibitors (ACEI) and an angiotensin II blocker (AIIB). At the same time they examined a control group of 24 patients untreated with ACEI and AIIB. All the patients received combined antituberculous therapy. Cardiac glycosides and diuctics were given in some cases. During 1-2 months, the patients from the experimental group additionally took captopril, 12.5-25.0 mg, twice a day or prestarium, 2.0-4.0 mg, once a day, or cossar, 50 mg, once a day. After the treatment, ACEI and AIIB were found to have no effect on blood gas and electrolyte composition, and respiratory and renal functions. With captopril and ramipril there was a higher patency of minor bronchi in the experimental groups than in the controls.
A E
AE
Ditiatkov
A E
AE
Radzevich
V A
VA
Tikhonov
P A
PA
Zholnin
G V
GV
Mal'gina
D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D000995:Antitubercular Agents / Q000627:therapeutic use; D004573:Electrolytes / Q000097:blood*; D005260:Female; D006333:Heart Failure / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007677:Kidney Function Tests; D019808:Losartan / Q000627:therapeutic use*; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D014797:Vital Capacity / Q000502:physiology*
D000889:Anti-Arrhythmia Agents; D000995:Antitubercular Agents; D004573:Electrolytes; D019808:Losartan