[Subpopulation composition of human blood lymphocytes/monocytes in patients with acute viral hepatitis B and C].
The number of lymphocytes/monocytes in peripheral blood was determined in 105 patients with viral hepatitis B, viral hepatitis C and mixed hepatitis, as well as in 44 clinically healthy donors. The diagnosis of viral hepatitis was verified using the standard set of viral, biochemical, including PCR, and instrumental tests. Acute viral hepatitis B and C infections were shown to be accompanied by a considerable decrease in the number of lymphocytes CD22+ in comparison with that in healthy donors. In mixed hepatitis changes in the subpopulation composition also affected cells CD16+. In load tests with biogenic amines changes in the capacity of lymphocytes to express CD8, CD16 and HLA-DR markers were established.
Medical Institute Reaviz, Samara, Russia.
M V
MV
Kalyshenko
I P
IP
Balmasova
D000208:Acute Disease; D000328:Adult; D015703:Antigens, CD / Q000032:analysis; D000944:Antigens, Differentiation, B-Lymphocyte / Q000032:analysis; D001679:Biogenic Amines; D016827:CD8 Antigens / Q000032:analysis; D015815:Cell Adhesion Molecules; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis; D006509:Hepatitis B / Q000097:blood*; D006526:Hepatitis C / Q000097:blood*; D006801:Humans; D037102:Lectins; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D017452:Receptors, IgG / Q000032:analysis; D051918:Sialic Acid Binding Ig-like Lectin 2
D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; D001679:Biogenic Amines; C497867:CD22 protein, human; D016827:CD8 Antigens; D015815:Cell Adhesion Molecules; D006684:HLA-DR Antigens; D037102:Lectins; D017452:Receptors, IgG; D051918:Sialic Acid Binding Ig-like Lectin 2