Breast pain and mammographic density increase as a consequence of raloxifene therapy.
A 55-yr-old post-menopausal woman with osteopenia and no history of breast disease is presented. She was placed on raloxifene HCl 60 mg and soon after developed severe breast pain. The follow-up mammogram, performed prematurely at 6 months, showed a marked increase in breast density. Therapy was accordingly stopped and mastodynia subsided. The patient's mammogram regressed to pre-treatment status after 6 months off-therapy.
Christodoulakos
G E
GE
2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Greece. ilambrinoudaki@hotmail.com
Lambrinoudaki
I V
IV
Vourtsi
A D
AD
Panoulis
K P
KP
Creatsas
G C
GC
D001851:Bone Diseases, Metabolic / Q000188:drug therapy; D001940:Breast / Q000473:pathology*; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D010146:Pain; D020849:Raloxifene Hydrochloride / Q000009:adverse effects*; D020845:Selective Estrogen Receptor Modulators / Q000009:adverse effects*
D020845:Selective Estrogen Receptor Modulators; D020849:Raloxifene Hydrochloride