[Orthotopic liver transplantation with no veno-venous bypass].
OBJECTIVE
To assess the feasibility and outcome of orthotopic liver transplantation (OLT) with no veno-venous bypass (VVB) in adult patients.


METHODS
Between 1999 and June 2001, 43 adult patients were subjected to orthotopic liver transplantations with veno-venous bypass (28), or no veno-venous bypass (15).


RESULTS
There was no significant difference in mean serum creatinine on day 3 and gas discharge time in patients with veno-venous bypass or not. With no veno-venous bypass, the average operative time was 5.6 +/- 1.4 h, median amount of blood loss during operation was 4 200 +/- 850 ml, median amount of blood transfused intraoperatively was 4 800 +/- 920 ml, and median intensive care unit stay was 6.3 days. All these were lower or shorter than those of the patients with veno-venous bypass.


CONCLUSIONS
Orthotopic liver transplantation with no veno-venous bypass is safe and can be performed in the majority of adult patients. Liver transplantation with no veno-venous bypass is associated with shorter total operating time, lower blood product usage, and shorter intensive care unit stay compared with standard technique of OLT with routine use of VVB.
Department of Hepatobiliary Surgery, First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou 310003, China.
Shusen
S
Zheng
Dongsheng
D
Huang
Jian
J
Wu
Weilin
W
Wang
Yan
Y
Shen
Min
M
Zhang
Qingyun
Q
Shen
Anwei
A
Lu
Peifen
P
Fu
Xiao
X
Xu
D000328:Adult; D003404:Creatinine / Q000097:blood; D005240:Feasibility Studies; D005260:Female; D006503:Hepatic Veins / Q000601:surgery*; D006801:Humans; D008107:Liver Diseases / Q000097:blood / Q000601:surgery / Q000628:therapy; D016031:Liver Transplantation / Q000379:methods; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D014656:Vascular Surgical Procedures
D003404:Creatinine