Role of pronase E in ligand binding to Fc receptors in the reaction of cytotoxicity mediated by bovine blood neutrophils.
We studied the effects of pronase E on IgG binding to Fcg receptors on bovine blood neutrophils and kinetic parameters of this reaction (association constant and number of binding sites on neutrophils). During in vitro modeling of the cell immune response, we evaluated cytotoxic activity of effector neutrophils against foreign cells.
Institute of Biochemistry, Vilnius.
V V
VV
Milyukene
Ya L
YL
Dedinene
A M
AM
Aleksene
D000818:Animals; D002417:Cattle; D003602:Cytotoxicity, Immunologic; D007700:Kinetics; D008024:Ligands; D009504:Neutrophils / Q000276:immunology* / Q000378:metabolism; D011402:Pronase / Q000378:metabolism*; D011485:Protein Binding; D011961:Receptors, Fc / Q000378:metabolism*
D008024:Ligands; D011961:Receptors, Fc; D011402:Pronase