RNA chaperones exist and DEAD box proteins get a life.
The RNA chaperone hypothesis suggests the existence of proteins that resolve misfolded RNA structures in vivo. A recent study has found an RNA-dependent ATPase that functions in this manner.
Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA. jlorsch@jhmi.edu
Jon R
JR
Lorsch
D020816:Amino Acid Motifs; D000818:Animals; D034441:Heterogeneous-Nuclear Ribonucleoproteins; D018832:Molecular Chaperones / Q000737:chemistry* / Q000378:metabolism*; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry* / Q000378:metabolism*; D020365:RNA Helicases / Q000737:chemistry / Q000378:metabolism; D012326:RNA Splicing; D012261:Ribonucleoproteins / Q000737:chemistry / Q000378:metabolism
D034441:Heterogeneous-Nuclear Ribonucleoproteins; D018832:Molecular Chaperones; D012261:Ribonucleoproteins; D012313:RNA; D020365:RNA Helicases