First examples of the catalytic asymmetric ring-opening of meso 1,2-dioxines utilising cobalt(II) complexes with optically active tetradentate Schiff base ligands: formation of enantio-enriched cyclopropanes.
The combination of chiral cobalt beta-ketoiminato or cobalt salen complexes and meso 1,2-dioxines leads to catalytic asymmetric ring-opening affording enantio-enriched cis gamma-hydroxy enones; subsequent capture by an ylide affords enantio-enriched cyclopropanes.
Avery
Thomas D
TD
Department of Chemistry, Adelaide University, South Australia, Australia, 5005.
Jenkins
Natalie F
NF
Kimber
Marc C
MC
Lupton
David W
DW
Taylor
Dennis K
DK