[Effect of sulodexide on hemocoagulation and lipid peroxidation in athletes during physical load].
High physical loads lead to an increase in the blood coagulation rate and inhibit fibrinolysis in athletes. At the same time, the fibrin-stabilizing factor activity and the fibrinogen concentration tend to increase. Sulodexide produces an anticoagulant effect, thus preventing from hypercoagulation. An increase in the working capacity of athletes caused by suloxide administration is accompanied by the antioxidant action.
Laboratory of Clinical Pharmacology and Antidoping Monitoring, Moscow Scientific-Practical Center of Sport Medicine, Zemlyanoi Val 8, Moscow, 107120 Russia.
O A
OA
Mukhanov
Z G
ZG
Ordzhonikidze
V G
VG
Lioshenko
R D
RD
Seĭfulla
D000328:Adult; D000925:Anticoagulants / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D001777:Blood Coagulation / Q000187:drug effects*; D005342:Fibrinolysis / Q000187:drug effects; D006025:Glycosaminoglycans / Q000494:pharmacology*; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male
D000925:Anticoagulants; D000975:Antioxidants; D006025:Glycosaminoglycans; C007858:glucuronyl glucosamine glycan sulfate