Chronological change of brain abscess in (1)H magnetic resonance spectroscopy.
We studied chronological magnetic resonance spectral changes in brain abscesses before and after medical and/or surgical treatment. We examined five patients with MRI imaging and (1)H magnetic resonance spectroscopy (MRS) on two or more occasions, using two volume-of-interest patterns, and saw chronological changes related to the evolution of the abscess. A spectrum specific for brain abscess was found in three of the five cases, while two showed a single lactate peak in the first study. In two cases, phenylalanine or alanine appeared in the second study. We observed the disappearance of the specific spectra and a single lactate peak following surgery. Only one patient showed different spectra in different volume of interest.
Department of Neurosurgery, Institute of Clinical Medicine, University of Tsukuba, Tennodai 1-1-1,Tsukuba, Ibaraki 305-8575, Japan.
H
H
Akutsu
A
A
Matsumura
T
T
Isobe
I
I
Anno
S
S
Takano
Y
Y
Itai
T
T
Nose
D000293:Adolescent; D000328:Adult; D000368:Aged; D000409:Alanine / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D001922:Brain Abscess / Q000175:diagnosis* / Q000378:metabolism; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D010649:Phenylalanine / Q000378:metabolism; D013997:Time Factors
D000596:Amino Acids; D019344:Lactic Acid; D010649:Phenylalanine; D000409:Alanine