The versatile conversion of acyclic amides to alpha-alkylated amines.
A general and efficient method for the versatile functionalization of acyclic amide via N,O-acetal TMS ether, an excellent precursor for the N-acyliminium ion, has been developed.
Suh
Young-Ger
YG
College of Pharmacy, Seoul National University, San 56-1, Shinlim-dong, Kwanak-Gu, Seoul, Korea. ygsuh@snu.ac.kr
Shin
Dong-Yun
DY
Jung
Jae-Kyung
JK
Kim
Seok-Ho
SH