The temperament and character inventory in major depression.
Patients admitted for pharmacological treatment of a non-bipolar major depressive episode completed the Temperament and Character Inventory (TCI) prior to and after at least 6 weeks of treatment. Treatment with various antidepressants resulted in a 43% reduction of symptomatology. Scores on the harm avoidance dimension before and after treatment appeared to be significantly higher as compared to Dutch normative data. TCI scores did not predict response to treatment or show a change during treatment. It is concluded that, in this group of patients, the personality dimension harm avoidance is a trait factor without predictive value for antidepressant responsiveness.
Vincent van Gogh Institute for Psychiatry, Stationsweg 46, 5803 AC, Venray, The Netherlands.
G
G
Marijnissen
S
S
Tuinier
A E S
AE
Sijben
W M A
WM
Verhoeven
D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use; D002605:Character; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires; D013694:Temperament
D000928:Antidepressive Agents