Progesterone receptor expression in angioleiomyoma of the nasal cavity.
In recent years sex steroid receptors have been identified in several types of human neoplasia. Angioleiomyoma of the nasal cavity and paranasal sinus is an extremely rare benign neoplasm which is more common in females (3.75:1 female:male ratio). To the best of our knowledge, only approximately 25 cases have been described. We describe a new case of angioleiomyoma of the nasal cavity that was found to be progesterone-receptor positive and oestrogen-receptor negative on immunohistochemical analysis. We suggest that the growth of this tumour may be hormone-dependent.
Department of Otolaryngology, Head and Neck Surgery, University of Padua, Italy. g_marioni@virgilio.it
Gino
G
Marioni
Rosario
R
Marchese-Ragona
Severino
S
Fernandez
Juan
J
Bruzon
Filippo
F
Marino
Alberto
A
Staffieri
D000368:Aged; D018229:Angiomyoma / Q000378:metabolism* / Q000473:pathology; D003937:Diagnosis, Differential; D004727:Endothelium / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009130:Muscle, Smooth / Q000378:metabolism / Q000473:pathology; D009296:Nasal Cavity / Q000378:metabolism / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000378:metabolism* / Q000473:pathology; D011980:Receptors, Progesterone / Q000378:metabolism*
D011980:Receptors, Progesterone