Handgrip strength and mortality in older Mexican Americans.
OBJECTIVE
To examine the association between handgrip strength and mortality in older Mexican American men and women.


METHODS
A 5-year prospective cohort study.


METHODS
Five southwestern states: Texas, New Mexico, Colorado, Arizona, and California.


METHODS
A population-based sample of 2,488 noninstitutionalized Mexican-American men and women aged 65 and older.


METHODS
Maximal handgrip strength, timed walk, and body mass index were assessed at baseline during 1993/94. Self-reports of functional disability, various medical conditions, and status at follow-up were obtained.


RESULTS
Of the baseline sample with complete data, 507 persons were confirmed deceased 5 years later. Average handgrip strength +/- standard deviation was significantly higher in men (28.4 kg +/- 9.5) than in women (18.2g +/- 6.5). Of men who had a handgrip strength less than 22.01 kg and women who had a handgrip strength less than 14 kg, 38.2% and 41.5%, respectively, were dead 5 years later. In men in the lowest handgrip strength quartile, the hazard ratio of death was 2.10 (95% confidence interval (CI) = 1.31-3.38) compared with those in the highest handgrip strength quartile, after controlling for sociodemographic variables, functional disability, timed walk, medical conditions, body mass index, and smoking status at baseline. In women in the lowest handgrip strength quartile, the hazard ratio of death was 1.76 (95%I = 1.05-2.93) compared with those in the highest handgrip strength quartile. Poorer performance in the timed walk and the presence of diabetes mellitus, hypertension, and cancer were also significant predictors of mortality 5 years later.


CONCLUSIONS
Handgrip strength is a strong predictor of mortality in older Mexican Americans, after controlling for relevant risk factors.
Department of Internal Medicine, Sealy Center on Aging, University of Texas Medical Branch, Galveston, Texas 77555, USA. soalsnih@utmb.edu
Soham
S
Al Snih
Kyriakos S
KS
Markides
Laura
L
Ray
Glenn V
GV
Ostir
James S
JS
Goodwin
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D004185:Disability Evaluation; D005260:Female; D015577:Geriatric Assessment; D018737:Hand Strength; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D008800:Mexico / Q000208:ethnology; D009026:Mortality; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D011446:Prospective Studies; D016019:Survival Analysis; D014481:United States / Q000453:epidemiology; D016138:Walking / Q000502:physiology