Energies and selectivities for anion binding as a function of host conformational preorganisation.
The anion binding of tripodal hosts 2-4 has been studied. Increasing levels of conformational preorganisation of the side arms of the hosts led to increased (Cl-) unaltered (Br-) or decreased (NO3-) binding; it was thus possible to change guest selectivities by about an order of magnitude through conformational preorganisation of the flexible host.
Fachbereich Chemie, Philipps-Universität Marburg, Hans-Meerwein-Strasse, D-35032 Marburg, Germany. rwho@chemie.uni-marburg.de
Reinhard W
RW
Hoffmann
Frank
F
Hettche
Klaus
K
Harms
D000838:Anions / Q000737:chemistry*; D001665:Binding Sites; D019143:Evolution, Molecular; D008024:Ligands; D008956:Models, Chemical; D008968:Molecular Conformation; D013816:Thermodynamics; D014508:Urea / Q000737:chemistry*
D000838:Anions; D008024:Ligands; D014508:Urea