Serological investigation of Bartonella henselae infections in clinically cat-scratch disease-suspected patients, patients with cardiovascular diseases, and healthy veterinary students in Japan.
Seroprevalence of Bartonella henselae was investigated in Japan in 48 individuals clinically suspected of having cat-scratch disease (CSD), 159 patients with cardiovascular diseases, and 129 healthy veterinary students. Of 48 CSD-suspected patients examined, 19 (39.6%) were positive for B. henselae-IgG and 4 (8.3%) for B. henselae-IgM. Of 159 patients with cardiovascular diseases, 5 (3.1%) were positive for B. henselae-IgG. In healthy veterinary students, 14 of 129 (10.9%) were positive for B. henselae-IgG and 1 (0.8%) for B. henselae-IgM. The positive rates of B. henselae-IgG and -IgM in CSD-suspected patients were significantly higher than in other sources. Most CSD-suspected and healthy individuals who were positive for B. henselae antibody had had some contacts with cats. In CSD-suspected patients, the B. henselae positive rate in females was significantly higher than in males, and high seropositive rates to B. henselae were found in younger age groups.
Kikuchi
Eisaku
E
Department of Veterinary Medicine, College Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan.
Maruyama
Soichi
S
Sakai
Takeo
T
Tanaka
Shigeo
S
Yamaguchi
Fukumitsu
F
Hagiwara
Toshikatsu
T
Katsube
Yasuji
Y
Mikami
Takeshi
T
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood; D001474:Bartonella Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D018416:Bartonella henselae / Q000302:isolation & purification*; D002318:Cardiovascular Diseases / Q000382:microbiology*; D002372:Cat-Scratch Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D012737:Sex Factors
D000907:Antibodies, Bacterial