Partial conduction blocks in N-hexane neuropathy.
Nerve conduction blocks, defined by a significant reduction in amplitude or area of the compound muscle action potential at proximal compared with distal sites of stimulation, have been described in glue-sniffers and in workers with industrial exposure at an early stage of n-hexane neuropathy. The frequency with which this focal conduction anomaly appears is described and discussed in the case of a very homogeneous group of 10 young workers diagnosed with n-hexane polyneuropathy. Partial conduction blocks occurred in only two workers and may have been related to the intensity and duration of toxic exposure.
Pastore
Carlos
C
Clinical Neurophysiology Unit (EMG), University Hospital of San Juan, Carretera Alicante-Valencia s/n, 03550 San Juan, Alicante, Spain. Carlos.Pastore@ua.es
Izura
Virginia
V
Marhuenda
Dolores
D
Prieto
María-José
MJ
Roel
José
J
Cardona
Antonio
A
D000200:Action Potentials / Q000187:drug effects; D000293:Adolescent; D000328:Adult; D004568:Electrodiagnosis; D004784:Environmental Monitoring; D005260:Female; D006586:Hexanes / Q000506:poisoning*; D006588:Hexanones / Q000652:urine; D006801:Humans; D007221:Industry; D019570:Inhalation Exposure; D008475:Median Nerve / Q000187:drug effects / Q000503:physiopathology; D009431:Neural Conduction / Q000187:drug effects*; D016273:Occupational Exposure; D011115:Polyneuropathies / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology*; D013979:Tibial Nerve / Q000187:drug effects / Q000503:physiopathology; D013995:Time
D006586:Hexanes; D006588:Hexanones; C026385:n-hexane; C011269:2,5-hexanedione