Paradoxical response to apomorphine in a case of atypical parkinsonism.
We describe a patient with clinical signs of parkinsonism showing a paradoxical response to apomorphine injection. We discuss possible pathogenetic mechanisms with regard to the literature and suggest the diagnosis of a striatonigral degeneration at an early stage.
Cicarelli
Giulio
G
Department of Neurological Sciences, Università Federico II, Napoli, Italy.
Pellecchia
Maria Teresa
MT
De Michele
Giuseppe
G
Pizzolato
Gilberto
G
Barone
Paolo
P
D000978:Antiparkinson Agents; D001058:Apomorphine; D018491:Dopamine Agonists / Q000627:therapeutic use*; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020734:Parkinsonian Disorders / Q000175:diagnosis* / Q000188:drug therapy; D015899:Tomography, Emission-Computed, Single-Photon; D017211:Treatment Failure
D000978:Antiparkinson Agents; D018491:Dopamine Agonists; D007980:Levodopa; D001058:Apomorphine