Diagnostic intraocular aspiration cytology of choroidal melanoma.
Fine-needle aspiration cytology (FNAC) was performed on an intraocular mass in a 32-yr-old Indian woman and a cytologic diagnosis of malignant melanoma was made, supported by immunocytochemistry. The cytologic features included spindle-shaped tumour cells with minimal pleomorphism and the presence of nuclear grooves. No intracellular pigment was identified; however, positivity for HMB-45 allowed a rapid and reliable diagnosis. The utility of FNAC in an atypical presentation of choroidal melanoma is discussed.
Kashyap
Seema
S
Department of Ocular Pathology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, New Delhi 110029, India. lokeshkashyap@yahoo.com
Sen
Seema
S
Sharma
M C
MC
Sethi
Anita
A
D000328:Adult; D000951:Antigens, Neoplasm; D001707:Biopsy, Needle; D002830:Choroid Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008545:Melanoma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins / Q000032:analysis
D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins