Practical tethering of vitamin B1 on a silica surface via its phosphate group and evaluation of its activity.
A convenient immobilization of thiamine pyrophosphate molecules on a silica surface through the phosphate group is developed, leading to a very active heterogenized biocatalyst for pyruvate decarboxylation.
Vartzouma
Ch
Ch
Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Louloudi
M
M
Butler
I S
IS
Hadjiliadis
N
N
D002384:Catalysis; D003432:Cross-Linking Reagents / Q000737:chemistry; D003653:Decarboxylation; D010710:Phosphates; D011767:Pyruvate Decarboxylase / Q000378:metabolism; D019289:Pyruvic Acid / Q000378:metabolism*; D012822:Silicon Dioxide; D013831:Thiamine / Q000737:chemistry* / Q000378:metabolism; D013835:Thiamine Pyrophosphate / Q000737:chemistry / Q000378:metabolism
D003432:Cross-Linking Reagents; D010710:Phosphates; D012822:Silicon Dioxide; D019289:Pyruvic Acid; D011767:Pyruvate Decarboxylase; D013835:Thiamine Pyrophosphate; D013831:Thiamine