Combinatorial development of chiral phosphoramidite-ligands for enantioselective conjugate addition reactions.
Chiral phosphoramidite ligands embodying bispidine frame work and a binaphthyl phosphoramidite for Cu-catalysed enantioselective conjugate addition reactions were developed employing principles of combinatorial and solid phase chemistry.
Max-Planck-Institut für molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Str. 11, 44227 Dortmund, Germany.
Oliver
O
Huttenloch
Eltepu
E
Laxman
Herbert
H
Waldmann
D000475:Alkenes / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D007659:Ketones / Q000737:chemistry; D008024:Ligands; D010756:Phosphoric Acids / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D000577:Amides; D007659:Ketones; D008024:Ligands; D010756:Phosphoric Acids; C011067:phosphoramidic acid