An Emerging Field in Bioscience High Hydrostatic Pressure Study.
The goal of this mini review is to explain how hydrostatic pressure acts on bio-macromolecules(mainly on protein), giving some basic knowledge. Moreover, it will be shown that high pressure is a powerful tool both for the study of bio-macromolecules such as protein conformation, protein-protein (or protein-nucleic acid, or protein-ligands) interactions and the modulation of enzymatic activity etc. and for study of biotechnological application.
INSERM U 128, IFR 24, CNRS, 1919, Route de Mende, 34297 Montpellier Cedex 5, France. balny@crbm.cnrs-mop.fr
Claude
C
Balny
Kang-Cheng
KC
Ruan