Corticobasal degeneration syndrome with basal ganglia calcification: Fahr's disease as a corticobasal look-alike?
A 57-year-old man with a 5-year history of progressive left-sided rigidity and apraxia had extensive bilateral calcification of basal ganglia, centrum semiovale, dentate nuclei, and cerebellar white matter on brain imaging. The case is an example of radiological Fahr's disease accompanying a clinical syndrome of corticobasal degeneration. Possible pathogenetic and nosological implications of this association are discussed.
The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.
Jason D
JD
Warren
Catherine J
CJ
Mummery
Amir S
AS
Al-Din
Peter
P
Brown
Nicholas W
NW
Wood
D001480:Basal Ganglia Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002114:Calcinosis / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019636:Neurodegenerative Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D013577:Syndrome; D014057:Tomography, X-Ray Computed