Aminoglycoside antibiotics bind to protein disulfide isomerase and inhibit its chaperone activity.
Horibe
Tomohisa
T
Nagai
Hiroaki
H
Matsui
Hiroaki
H
Hagiwara
Yasunari
Y
Kikuchi
Masakazu
M
D000617:Aminoglycosides; D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D015374:Biosensing Techniques; D002417:Cattle; D018832:Molecular Chaperones / Q000037:antagonists & inhibitors*; D019704:Protein Disulfide-Isomerases / Q000378:metabolism*; D014640:Vancomycin / Q000378:metabolism*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D018832:Molecular Chaperones; D014640:Vancomycin; D019704:Protein Disulfide-Isomerases