Pulmonary hyalinizing granuloma with hydronephrosis.
A 49-year-old man was admitted for the evaluation of a bilateral mass shadow in his chest X-ray film. No definitive diagnosis was established either by brushing cytology or biopsy through bronchoscopy. No malignancies were suggested by general work-up. Both masses were surgically removed, and were diagnosed as pulmonary hyalinizing granuloma (PHG). Fifteen months later, low grade fever continued and the renal function decreased. Laboratory examinations revealed bilateral hydronephrosis with polyclonal hypergammaglobulinemia. The findings of abdominal CT and urography were compatible with retroperitoneal fibrosis. Steroid treatment completely reversed the initial abnormality in laboratory data and the symptoms disappeared.
Department of Nephrology, Sapporo City General Hospital, Hokkaido.
Seiji
S
Hashimoto
Wataru
W
Fujii
Tatsurou
T
Takahashi
Koichi
K
Shiroshita
Tetsuo
T
Sakurai
Takahiro
T
Ueda
Tetsuya
T
Kawata
D005938:Glucocorticoids / Q000627:therapeutic use; D015769:Granuloma, Respiratory Tract / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D006818:Hyalin / Q000378:metabolism; D006869:Hydronephrosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D013902:Radiography, Thoracic; D012185:Retroperitoneal Fibrosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D005938:Glucocorticoids; D011239:Prednisolone