[Brain metastases].
The incidence of symptomatic brain metastases in Denmark is about 3500. In the present review, the aetiology, symptomatology, and diagnostic procedures are described. The main topic is a review of current treatments and the evidence for their efficacy. Treatment of brain metastases rarely cures the patient, the goal is rather to improve the quality of life and prolong survival. Without treatment, the median survival following diagnosis of brain metastases is about one month, with steroid treatment two months, with whole brain irradiation four to six months, and after surgery or stereotactic radiosurgery 10-12 months. A relatively simple treatment scheme based on the number of brain metastases and the overall condition of the patient is provided.
Brennum
Jannick
J
Neurokirurgisk afdeling, H:S Rigshospitalet, DK-2100 København ø. brennum@dadlnet.dk
Kosteljanetz
Michael
M
Roed
Henrik Michael H
HM
D001932:Brain Neoplasms / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D003718:Denmark / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D015996:Survival Rate