The omp-1 major outer membrane multigene family of Ehrlichia chaffeensis is differentially expressed in canine and tick hosts.
Sixteen of 22 omp-1 paralogs encoding 28-kDa-range immunodominant outer membrane proteins of Ehrlichia chaffeensis were transcribed in blood monocytes of dogs throughout a 56-day infection period. Only one paralog was transcribed by E. chaffeensis in three developmental stages of Amblyomma americanum ticks before or after E. chaffeensis transmission to naïve dogs.
Department of Veterinary Biosciences, The Ohio State University, Columbus 43210-1093, USA.
Ahmet
A
Unver
Yasuko
Y
Rikihisa
Roger W
RW
Stich
Norio
N
Ohashi
Suleyman
S
Felek
D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D004195:Disease Models, Animal; D004285:Dogs; D018469:Ehrlichia chaffeensis / Q000235:genetics*; D016873:Ehrlichiosis / Q000382:microbiology*; D015870:Gene Expression; D005798:Genes, Bacterial; D008297:Male; D005810:Multigene Family; D012336:RNA, Ribosomal, 16S; D013987:Ticks / Q000382:microbiology
D001425:Bacterial Outer Membrane Proteins; D012336:RNA, Ribosomal, 16S