Serrated adenoma developing into advanced colon cancer in 2 years.
We report the case of a 76-year-old woman with a flat elevated lesion (laterally spreading tumor; LST) in the transverse colon that had been identified 2 years before the current presentation. Pathologically, the lesion had been diagnosed as a serrated adenoma with severe dysplasia. The patient had refused endoscopic resection because she was afraid of the risk of colonic perforation; she did not come to follow-up until 2 years after the diagnosis, when she had advanced colon cancer in the transverse colon where the LST had been detected. Histopathological examination confirmed a poorly differentiated adenocarcinoma with no adenomatous component such as had been found in the LST lesion.
Department of Surgery, School of Medicine, Keio University, Tokyo, Japan.
Takeyoshi
T
Yamauchi
Masahiko
M
Watanabe
Hirotoshi
H
Hasegawa
Seiichiro
S
Yamamoto
Takashi
T
Endo
Yasuo
Y
Kabeshima
Kyoko
K
Yorozuya
Kentaro
K
Yamamoto
Masaki
M
Kitajima
D000230:Adenocarcinoma / Q000473:pathology*; D000236:Adenoma / Q000473:pathology*; D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans