Two epimeric flavalignans from Trichilia catigua (Meliaceae) with antimicrobial activity.
A mixture of flavalignan cinchonains Ia and Ib was isolated from the bark of Trichilia catigua. The structures were established on the basis of spectroscopic data of the natural products and their methylated derivatives including 2D NMR experiments, and compared with data in the literature. These flavalignans exhibited antibacterial activity against Bacillus
Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis-SC, Brazil. moacir@qmc.ufsc.br
Moacir G
MG
Pizzolatti
Andreia F
AF
Venson
Artur
A
Smânia
Elza de F A
Ede F
Smânia
Raimundo
R
Braz-Filho
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007536:Isomerism; D029582:Meliaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
D000900:Anti-Bacterial Agents; D005419:Flavonoids; D010936:Plant Extracts