Highly emissive, nine-coordinate enantiopure lanthanide complexes incorporating tetraazatriphenylenes as probes for DNA.
The interaction of q = 0 delta- and lambda-Tb and Eu complexes with poly(dAdT), poly(dGdC) and calf-thymus DNA has been examined by absorption, emission and chiroptical spectroscopy and is sensitive to complex helicity, base-pair type and the nature of the lanthanide excited state.
Department of Chemistry, University of Durham, South Road, Durham, UK DH1 3LE.
Gabriella
G
Bobba
Juan C
JC
Frias
David
D
Parker
D002911:Chrysenes / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D015342:DNA Probes / Q000737:chemistry*; D007700:Kinetics; D028581:Lanthanoid Series Elements / Q000737:chemistry* / Q000378:metabolism; D008024:Ligands; D015394:Molecular Structure; D013053:Spectrophotometry / Q000379:methods
D002911:Chrysenes; D015342:DNA Probes; D028581:Lanthanoid Series Elements; D008024:Ligands; C009590:triphenylene; D004247:DNA; C427203:calf thymus DNA