Carbamazepine- induced hypertension.
A 33-year-old man with complex partial seizures developed de novo hypertension after the initiation of carbamazepine, which resolved on discontinuation. Although rare, a variety of cardiovascular effects including hypertension have been reported with carbamazepine. Numerous mechanisms may be responsible; however, shared pharmacologic properties with the tricyclic antidepressants are suspect. Hypertension is a rare side effect of carbamazepine.
Division of Neurology, The Ottawa Hospital, University of Ottawa, Ontario, Canada.
Nathalie
N
Jette
Tim
T
Veregin
Alan
A
Guberman
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D002220:Carbamazepine / Q000008:administration & dosage / Q000009:adverse effects*; D017029:Epilepsy, Complex Partial / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D008297:Male
D000927:Anticonvulsants; D002220:Carbamazepine