[Use of domestic thromboplastins with attested international indices of sensitivity in the treatment of thrombophilia].
Clinical evaluation of thromboplastins manufactured by RENAM (Moscow) with international index of sensitivity (IIS) 1.1-1.5 and comparison of the results with the data obtained in the same patients with foreign thromboplastins (Dade, USA; Behring, Germany; Diamed, Switzerland) and Mediolab thromboplastins (Russia) manufactured from different raw materials (rabbit brain and human placenta) showed that by sensitivity to indirect anticoagulants, Russian thromboplastins made by RENAM and Mediolab firms are not inferior to the best foreign analogs.
Kachalova
N D
ND
Klimovich
L G
LG
Berkovskiĭ
A L
AL
Prostakova
T M
TM
Kozlov
A A
AA
D000284:Administration, Oral; D000818:Animals; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D019934:International Normalized Ratio; D010630:Phenindione / Q000008:administration & dosage / Q000627:therapeutic use; D011517:Prothrombin Time; D011817:Rabbits; D012426:Russia; D013514:Surgical Procedures, Operative; D015912:Thrombolytic Therapy; D013925:Thromboplastin / Q000592:standards; D013927:Thrombosis / Q000097:blood* / Q000517:prevention & control
D000925:Anticoagulants; D010630:Phenindione; D013925:Thromboplastin