[The effect of hyperlipidemia on hearing function].
OBJECTIVE
We evaluated the effects of hyperlipidemia on hearing function.


METHODS
The study included 274 hyperlipidemic patients (176 females, 98 males; age range 35 to 60 years) who manifested normal tympanic membrane findings, no history of noise exposure, and chronic systemic or ear diseases. Sixty healthy subjects (36 females, 24 males) with normal serum lipid levels were enrolled as controls. Subjects who had elevated serum total cholesterol, triglyceride, and very low density lipoprotein (VLDL) levels, and normal lipid levels were divided into four groups and their hearing functions were analysed with pure-tone audiometry.


RESULTS
Evaluation of all groups showed significantly increased hearing levels at three frequencies in female patients, and at six frequencies in male patients (p < 0.05). Significant increases in hearing levels were observed both in females and males at 8000 Hz in three groups, at 6000 Hz in the VLDL group, and in males at 2000 Hz in the total cholesterol and VLDL groups (p < 0.05). When both female and male patients were evaluated together, the largest difference was detected in the VLDL group at five frequencies.


CONCLUSIONS
The findings of our study suggest that hyperlipidemia may have a role on the occurrence of sensorineural hearing loss.
Karlidağ
Turgut
T
Firat Universitesi Tip Fakültesi, Kulak Burun Boğaz Hastaliklari Anabilim Dali, Halk Sağliği Anabilim Dali, Elaziğ, Turkey. turgut_karlidag@yahoo.com
Açik
Yasemin
Y
Kaygusuz
Irfan
I
Yalçin
Sinasi
S
Güngör
M Yüksel
MY
Demirbağ
Erhan
E
D000328:Adult; D001301:Audiometry, Pure-Tone; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006309:Hearing / Q000502:physiology*; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol