Pest-managing efficacy of trans-asarone isolated from Daucus carota L. seeds.
The bioactive hexane extract of Daucus carota seed yielded 2,4,5-trimethoxybenzaldehyde (1), oleic acid (2), trans-asarone (3), and geraniol (4). Compounds 1-4 were evaluated for their mosquitocidal, nematicidal, antifeedant, and antimicrobial activities. Only trans-asarone was active in the assays performed, causing 100% mortality to fourth-instar mosquito larvae, Aedes aegyptii, at 200 microg mL(-1) and the nematodes Caenorhabditis elegans and Panagrellus redivivus at 100 microg mL(-1). In feeding trials, trans-asarone also caused significant weight reductions of the caterpillars Helicovarpa zea, Heliothis virescens, and Manduca sexta when incorporated into artificial diet at a concentration of 100 microg mL(-1). Also, it exhibited slight activity at 100 microg mL(-1) against the yeasts Candida albicans, Candida parapsilasis, and Candida kruseii.
Bioactive Natural Products and Phytoceuticals, Department of Horticulture and National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA.
Rafikali A
RA
Momin
Muraleeddharan G
MG
Nair
D000330:Aedes; D000081248:Allylbenzene Derivatives; D000818:Animals; D000840:Anisoles / Q000302:isolation & purification; D000969:Antinematodal Agents; D017173:Caenorhabditis elegans; D018552:Daucus carota / Q000737:chemistry*; D007306:Insecticides; D007814:Larva; D018402:Manduca; D009036:Moths; D010575:Pesticides; D010936:Plant Extracts / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*
D000081248:Allylbenzene Derivatives; D000840:Anisoles; D000969:Antinematodal Agents; D007306:Insecticides; D010575:Pesticides; D010936:Plant Extracts; C012195:asarone