[Perinatal outcome of twin pregnancies conceived by assisted reproductive techniques and those conceived spontaneously].
OBJECTIVE
To investigate perinatal outcomes of twin pregnancies conceived by assisted reproductive techniques and those conceived spontaneously.


METHODS
The pregnant complications, delivery situation and neonatal outcomes of 104 twin pregnancies conceived by assisted reproductive techniques were compared to 173 spontaneous ones.


RESULTS
(1) The women of twin pregnancies conceived by assisted reproductive techniques were (31.2 +/- 3.7) years old while the spontaneous ones were (27.8 +/- 3.5) years old. There was significant difference between two groups (P < 0.05). (2) There were also significant differences in the incidence of premature delivery and gestational diabetes mellitus or impaired glucose tolerance(P < 0.01) between two groups. There were 70 cases (67.3%) premature delivery in assisted reproduction group, while 78 cases (45.1%) in spontaneous group. There were 16 cases (15.4%) gestational diabetes mellitus or impaired glucose tolerance in assisted reproduction group, while 4 cases (2.3%) in spontaneous group. (3) Cesarean sections were more frequently performed in assisted reproduction group (79 cases, 76.0%) than in spontaneous group (113 cases 65.3%). (4) There were no statistically significant differences in perinatal deaths, congenital malformations, neonatal asphyxia between two groups (P < 0.05).


CONCLUSIONS
The women of twin pregnancies conceived by assisted reproductive techniques were older than those conceived spontaneously. The incidence of premature delivery, gestational diabetes mellitus or impaired glucose tolerance and cesarean section were higher in assisted reproduction group. However, no statistically significant differences in perinatal morbidity were found between the two groups.
Department of Obstetrics and Gynecology, First Affiliated Hospital of Sun Yet-  sen University of Medical Science, Guangzhou 510080, China.
Runcai
R
Liang
Yanmin
Y
Luo
Guoliang
G
Li
Wanting
W
Yu
D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data; D016640:Diabetes, Gestational / Q000453:epidemiology; D005260:Female; D005313:Fetal Death / Q000453:epidemiology; D005865:Gestational Age; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008423:Maternal Age; D007752:Obstetric Labor, Premature / Q000453:epidemiology / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D027724:Reproductive Techniques, Assisted; D014427:Twins