Primary paranasal Aspergillus granuloma: case report and review of the literature.
BACKGROUND
Primary paranasal aspergillus granuloma (PPAG) is a slowly progressive chronic infection of the sinus extending beyond the confines of the sinus. It has been reported only in patients from the Sudan and India. Microscopically, it differs from chronic invasive fungal sinusitis in that there are pseudotubercles containing giant cells, histiocytes, lymphocytes, plasma cells, newly formed capillaries, eosinophils, and Aspergillus fungal elements.


CONCLUSIONS
We describe the first case of PPAG in the United States in an immunocompetent nonatopic woman who had never left Missouri.
Department of Otolaryngology-Head and Neck Surgery, St Louis University School of Medicine, Missouri, USA.
John
J
Currens
Patricia S
PS
Hutcheson
Raymond G
RG
Slavin
Martin J
MJ
Citardi
D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis* / Q000601:surgery; D001707:Biopsy, Needle; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006099:Granuloma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D010254:Paranasal Sinus Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000601:surgery; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome