Multicentric reticulohistiocytosis. The long course of a rare disease.
Multicentric reticulohistiocytosis is a rare systemic disease. The patients usually develop an erosive polyarthritis in a few years. The most effective treatment is still unclear due to the few reports published of this disease. We report a case of multicentric reticulohistiocytosis with clinical, histopathologic and immunohistochemical study. The patient was treated with cyclophosphamide and nonsteroidal antiinflammatory drugs with an infrequent long-term survival.
Servicios de Medicina Interna y Anatomía Patológica, Madrid, Spain. jriosbl@nexo.es
Juan José Ríos
JJ
Blanco
Francisco Javier Barbado
FJ
Hernández
Jorge Gómez
JG
Cerezo
Inés Suárez
IS
García
Félix Contreras
FC
Rubio
Juan José Vázquez
JJ
Rodríguez
D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D005384:Finger Joint / Q000000981:diagnostic imaging / Q000473:pathology; D015616:Histiocytosis, Non-Langerhans-Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008264:Macrophages / Q000473:pathology; D008297:Male; D011859:Radiography
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide