Helical structure of heterochiral RNA dimers: helical sense of ApA is determined by chirality of 3'-end residue.
Heterochiral ApAs (ALpAL and ALpAL) have been synthesized and investigation of their helical structures by means of spectroscopic techniques indicates that the chirality of the 3'-end residue is the primary factor for determining the helical sense of ApA.
Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. urata@gly.oups.ac.jp
Hidehito
H
Urata
Makiko
M
Go
Norihiko
N
Ohmoto
Katsuhiko
K
Minoura
Masao
M
Akagi
D019281:Dimerization; D015226:Dinucleoside Phosphates / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*; D013057:Spectrum Analysis; D013237:Stereoisomerism
D015226:Dinucleoside Phosphates; C026520:adenosine monophosphate-adenosine; D012313:RNA