Hydroxy-substituted oligopyridine dicarboxamide helical foldamers.
As shown by X-ray diffraction and NMR studies, short oligopyridine dicarboxamides bearing benzyloxy, hydroxy and hydroxylate moieties adopt very robust single helical conformations, even in water.
Huc
Ivan
I
Institut Européen de Chimie et Biologie, 16 av. Pey Berland, 33607 Pessac, France. i.huc@iecb-polytechnique.u-bordeaux.fr
Maurizot
Victor
V
Gornitzka
Heinz
H
Léger
Jean-Michel
JM
D006900:Hydroxylation; D008968:Molecular Conformation; D018716:Molecular Mimicry; D009757:Nylons / Q000737:chemistry*; D009842:Oligopeptides / Q000737:chemistry; D017433:Protein Structure, Secondary; D011725:Pyridines / Q000737:chemistry*
D009757:Nylons; D009842:Oligopeptides; D011725:Pyridines; C023666:pyridine