Malignant mixed mesodermal tumours: biology and clinical aspects.
Mixed mesodermal tumours (MMTs) are relatively rare gynaecological tumours that have been poorly studied in clinical and molecular terms. They are chemosensitive (at least initially), although ultimately they have a poor prognosis. The biology of the tumour is fascinating in view of its composition of both epithelial and mesenchymal entities. We review herein the literature on the clinical and biological aspects of this malignancy.
ICRF Medical Oncology Unit, MRC Building, Western General Hospital, EH4 2XU, Edinburgh, UK. charles.gourley@cancer.org.uk
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Gourley
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Al-Nafussi
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Abdulkader
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Smyth
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Gabra
D000970:Antineoplastic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D005833:Genital Neoplasms, Female / Q000209:etiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D018198:Mixed Tumor, Malignant / Q000209:etiology / Q000473:pathology / Q000628:therapy; D018199:Mixed Tumor, Mesodermal / Q000209:etiology / Q000473:pathology / Q000628:therapy; D011379:Prognosis
D000970:Antineoplastic Agents