Synthesis of novel BINOL-derived chiral bisphosphorus ligands and their application in catalytic asymmetric hydrogenation.
Some novel ortho-substituted BINOL-derived bisphosphorous ligands (o-BINAPO and o-NAPHOS) were synthesis from readily available (S)-BINOL; these ligands showed excellent enantioselectivities (up to 99% ee) in Rh(I)-catalyzed asymmetric hydrogenation of functionalized olefins.
Department of Chemistry, Pennsylvania State University, University Park, PA 16802, USA.
Yong-Gui
YG
Zhou
Xumu
X
Zhang
D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D008024:Ligands; D009284:Naphthols / Q000138:chemical synthesis* / Q000737:chemistry; D017553:Phosphorus Compounds / Q000737:chemistry*; D013237:Stereoisomerism
C406944:BINOL, naphthol; D008024:Ligands; D009284:Naphthols; D017553:Phosphorus Compounds; D006859:Hydrogen