Nuclear transfer and cloning.
The use of nuclear transfer in human reproductive and therapeutic cloning is reviewed with attention on the origins of this technology from its evolution to the present. The successes and limitations of mammalian reproductive cloning are itemized. A case is made against the use of human reproductive cloning to reproduce an existing person, based on the unacceptable risks to the embryo, fetus, or newborn. However, support is extended for human therapeutic cloning involving the derivation and use of embryonic stem cells to treat human disease.
Oregon Regional Primate Research Center, Division of Reproductive Sciences, 505 NW 185th Avenue, Beaverton, OR 97006, USA. Wolfd@ohsu.edu
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Wolf
D000818:Animals; D019976:Cloning, Organism / Q000379:methods; D004622:Embryo, Mammalian; D004992:Ethics, Medical; D005260:Female; D024861:Genetic Enhancement / Q000379:methods; D005821:Genetic Techniques; D006805:Human Experimentation; D006801:Humans; D053652:Nuclear Transfer Techniques; D011247:Pregnancy; D012107:Research Design; D033581:Stem Cell Transplantation