Subsystem organ function during coronary surgery.
Conventional coronary artery bypass grafting (CABG) carries a mortality rate of 1% to 2% in elective patients. However, despite advances in perfusion, anaesthetic, and surgical techniques cardiopulmonary bypass (CPB) is still associated with subsystem dysfunction. Off-pump coronary artery bypass grafting (OPCAB) has recently gained popularity as a potentially more physiological method to maintain the functional integrity of major organ systems. The review of observational reports, case-matched studies and prospective randomized trials seems to suggest that OPCAB surgery reduces postoperative subsystem organ dysfunction when compared with conventional coronary revascularisation.
Ascione
Raimondo
R
Bristol Heart Institute, University of Bristol, UK.
Al-Ruzzeh
Sharif
S
Amer
Khalid
K
Angelini
Gianni D
GD
D000818:Animals; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000379:methods / Q000592:standards; D006801:Humans; D007431:Intraoperative Complications; D009204:Myocardial Revascularization / Q000009:adverse effects; D010829:Physiological Phenomena; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*