Reorganization of motor representation in a patient with epilepsia partialis continua as shown by [O15]-labeled butanol positron emission tomography and functional magnetic resonance imaging.
The authors investigated a 38-year-old patient with focal cortical dysplasia in the right precentral cortex using positron emission tomography and functional magnetic resonance imaging to localize the hand and finger motor representations. The patient presented clinically with epilepsia partialis continua, supposed to originate from the perirolandic area harboring the cortical malformation. Both methods revealed an abnormal bilateral activation of motor cortex during left-hand finger movements. The results suggest that the so-called eloquent but nevertheless pathological dysplastic cortex accommodates motor representations.
Department of Neurology, University Hospital Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany. stoeckco@uni-duesseldorf.de
M C
MC
Stoeckel
A
A
Kleinschmidt
A
A
Ebner
O W
OW
Witte
R J
RJ
Seitz
D020001:1-Butanol; D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology*; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000503:physiopathology; D010104:Oxygen Radioisotopes; D014055:Tomography, Emission-Computed
D010104:Oxygen Radioisotopes; D020001:1-Butanol