[Morphofunctional characteristics of erythrocytes in chronic kidney failure and purulent intoxication].
The morphology of blood erythrocytes was examined under a scanning electron microscope and erythrocyte surface charge, lipid peroxidation on erythrocyte membranes, and blood viscosity were studied in 213 urological patients with chronic renal insufficiency (CRI) and purulent intoxication (PI) of different severity. CRI and PI were characterized by morphofunctional changes in erythrocytes, which depended on the type and severity of intoxication. Changes in erythrocyte morphology in CRI and PI were paralleled by a decrease in their negative surface charge and activation of lipid peroxidation. These parameters can serve as diagnostic tests for evaluation of the severity of intoxication.
M V
MV
Samoĭlov
O D
OD
Mishnev
Iu V
IuV
Kudriavtsev
A G
AG
Naumov
A P
AP
Danilkov
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004560:Electricity; D004910:Erythrocyte Membrane / Q000378:metabolism; D004912:Erythrocytes / Q000737:chemistry / Q000378:metabolism* / Q000473:pathology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications; D015227:Lipid Peroxidation; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D013492:Suppuration / Q000097:blood / Q000209:etiology; D014783:Viscosity