Investigations into the Pd-catalysed cross-coupling of phenylacetylene with aryl chlorides: simple one-pot procedure and the effect of ZnCl2 co-catalysis.
[PdCl(C6H3(OPPri2)2-2,6)] 1 catalyses the coupling of electron-rich, electron-neutral and electron-deficient aryl chlorides with phenylacetylene in the presence of ZnCl2 as cocatalyst to give the products in modest to excellent yields.
Eberhard
Michael R
MR
Department of Chemistry, University of Hawaii, Honolulu, Hawaii 96822, USA.
Wang
Zhaohui
Z
Jensen
Craig M
CM
D000114:Acetylene / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism*; D002384:Catalysis; D002712:Chlorides / Q000494:pharmacology*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis*; D006843:Hydrocarbons, Chlorinated / Q000138:chemical synthesis*; D010165:Palladium / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D017967:Zinc Compounds / Q000494:pharmacology*
D002712:Chlorides; D006841:Hydrocarbons, Aromatic; D006843:Hydrocarbons, Chlorinated; D017967:Zinc Compounds; C044736:phenylacetylene; D010165:Palladium; C016837:zinc chloride; D000114:Acetylene