Chiral induction controlled by aggregation of organometallics: trifluoromethylated aminoalcohols for chiral ligands in Et2Zn alkylation of benzaldehyde.
Chiral induction in the reaction of Et2Zn with PhCHO by fluorinated chiral amino alcohols was correlated to the extent of aggregation of Et2Zn species, which was estimated by manometric study.
Department of Applied Chemistry, Okayama University, Tsushimanaka 3-1-1, Okayama 700-8530, Japan. tkata@cc.okayama-u.ac.jp
Toshimasa
T
Katagiri
Yasuyuki
Y
Fujiwara
Satoshi
S
Takahashi
Nobuyuki
N
Ozaki
Kenji
K
Uneyama