Benign inflammatory pancreatic mucinous cystadenomas mimicking locally advanced cystadenocarcinomas. Presentation of 3 cases.
We report 3 cases of benign mucinous cystadenoma of the pancreas mimicking, both clinically and on imaging findings, locally advanced cystadenocarcinoma spreading to neighbouring organs (stomach, splenic and mesenteric vessels, and diaphragm). Surgical resection was performed in light of the suspicion of invasive carcinoma in all 3 cases. Histological examination of the resected specimens showed entirely benign mucinous cystadenomas associated with marked peri-tumoural inflammation that accounted for the pre-operative misdiagnoses. All 3 patients are alive 40, 47 and 54 months after surgery without evidence of tumour relapse. These cases indicate that surgery must be considered in patients with cystic tumour of the pancreas suggesting locally advanced cystadenocarcinoma, even when pre-operative imaging findings suggest tumour extension into neighbouring organs.
Medical-Surgical Federation of Hepatogastroenterology, Hôpital Beaujon, 100 Boulevard du Général Leclerc F-92118 Clichy, France.
Frédérique
F
Maire
Pascal
P
Hammel
Benoît
B
Terris
Valérie
V
Vilgrain
Dermot
D
O'Toole
Philippe
P
Levy
Jacques
J
Belghiti
Philippe
P
Ruszniewski
D000328:Adult; D003536:Cystadenocarcinoma / Q000276:immunology / Q000473:pathology*; D018291:Cystadenoma, Mucinous / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000276:immunology / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed