Partial conduction blocks in N-hexane neuropathy.
Nerve conduction blocks, defined by a significant reduction in amplitude or area of the compound muscle action potential at proximal compared with distal sites of stimulation, have been described in glue-sniffers and in workers with industrial exposure at an early stage of n-hexane neuropathy. The frequency with which this focal conduction anomaly appears is described and discussed in the case of a very homogeneous group of 10 young workers diagnosed with n-hexane polyneuropathy. Partial conduction blocks occurred in only two workers and may have been related to the intensity and duration of toxic exposure.
Clinical Neurophysiology Unit (EMG), University Hospital of San Juan, Carretera Alicante-Valencia s/n, 03550 San Juan, Alicante, Spain. Carlos.Pastore@ua.es
Carlos
C
Pastore
Virginia
V
Izura
Dolores
D
Marhuenda
María-José
MJ
Prieto
José
J
Roel
Antonio
A
Cardona
D000200:Action Potentials / Q000187:drug effects; D000293:Adolescent; D000328:Adult; D004568:Electrodiagnosis; D004784:Environmental Monitoring; D005260:Female; D006586:Hexanes / Q000506:poisoning*; D006588:Hexanones / Q000652:urine; D006801:Humans; D007221:Industry; D019570:Inhalation Exposure; D008475:Median Nerve / Q000187:drug effects / Q000503:physiopathology; D009431:Neural Conduction / Q000187:drug effects*; D016273:Occupational Exposure; D011115:Polyneuropathies / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology*; D013979:Tibial Nerve / Q000187:drug effects / Q000503:physiopathology; D013995:Time
D006586:Hexanes; D006588:Hexanones; C026385:n-hexane; C011269:2,5-hexanedione