Anticholinergic poisoning from a large dose of Scopolia extract.
Scopolia extract (SE) contains hyoscyamine and scopolamine, which are both anticholinergic. It is usually used as a patent medicine to treat gastrointestinal disorders, to relieve spasmotic discomfort, or to decrease the secretion of gastric acid. Poisoning by SE presents similar symptoms and signs as other types of anticholinergic poisoning. We report a case of severe anticholinergic poisoning after accidentally drinking 8 ml of SE. The patient presented with acute delirium and was successfully treated with physostigmine.
Department of Emergency Medicine, Taichung Veterans General Hospital, Chung-Sun Medical and Dental College, Taiwan.
Sheng-Wen
SW
Cheng
Wei-Hsiung
WH
Hu
Dong-Zong
DZ
Hung
Dar-Yu
DY
Yang
D000284:Administration, Oral; D018680:Cholinergic Antagonists / Q000008:administration & dosage / Q000506:poisoning*; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003693:Delirium / Q000139:chemically induced*; D062787:Drug Overdose; D006801:Humans; D008297:Male; D008875:Middle Aged; D010830:Physostigmine / Q000627:therapeutic use; D010936:Plant Extracts / Q000008:administration & dosage / Q000506:poisoning*; D032603:Scopolia / Q000737:chemistry*
D018680:Cholinergic Antagonists; D002800:Cholinesterase Inhibitors; D010936:Plant Extracts; D010830:Physostigmine