Corticobasal degeneration syndrome with basal ganglia calcification: Fahr's disease as a corticobasal look-alike?
A 57-year-old man with a 5-year history of progressive left-sided rigidity and apraxia had extensive bilateral calcification of basal ganglia, centrum semiovale, dentate nuclei, and cerebellar white matter on brain imaging. The case is an example of radiological Fahr's disease accompanying a clinical syndrome of corticobasal degeneration. Possible pathogenetic and nosological implications of this association are discussed.
Warren
Jason D
JD
The National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.
Mummery
Catherine J
CJ
Al-Din
Amir S
AS
Brown
Peter
P
Wood
Nicholas W
NW
D001480:Basal Ganglia Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002114:Calcinosis / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019636:Neurodegenerative Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D013577:Syndrome; D014057:Tomography, X-Ray Computed