[Pathological systems in CNS performance].
The occurrence of new pathological integrations from the altered nervous structures in the central nervous system (CNS) is a highly important mechanism of nervous disorders. At the level of systemic relations, such an integration represents a new pathodynamic arrangement from the primarily and secondary altered formations of the CNS. The results of its performance are of a biologically negative, pathogenic value for the body. So such a pathodynamic arrangement is determined by the author as a pathological system (PS). PS substantially and basically differs from the physiological system in the mechanisms of occurrence, clinical manifestations, and performance results. PS is formed and fixed due to the plastic processes intrinsic to the nervous system, under the influence of the pathological determinant the hyperactive CNS formation that can also determine the nature of PS activity. The pathological systems are a pathobiological basis and a pathophysiological mechanism of neuropathological syndromes that are a clinical manifestation of PS performance. Each neuropathological syndrome has its PS. The pathological systems may consist of different formations, levels, and spheres of CNS performance, which determines the content of neuropathological syndromes, including those applied to higher nervous performance, behavior, and the mental sphere.
Kryzhanovskiĭ
G N
GN
D000818:Animals; D001526:Behavioral Symptoms / Q000503:physiopathology*; D001921:Brain / Q000473:pathology / Q000503:physiopathology*; D002493:Central Nervous System Diseases / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008954:Models, Biological; D013239:Stereotyped Behavior / Q000187:drug effects / Q000502:physiology; D013577:Syndrome; D013598:Systems Theory