Early occurring neuronal migration and maturation disorders.
This case report presents severe malformations of the central nervous system as a result of a pathological process occurring very early during development. Abnormal maturation and migration of neuroblasts were seen in all cerebral structures. Such changes are most often genetically determined, but in our case the analysis of their aetiology was not available.
Dambska
Maria
M
Department of Developmental Neuropathology, Medical Research Centre, Polish Academy of Sciences, Warszawa. dambska@cmdik.pan.pl
D061085:Agenesis of Corpus Callosum; D002465:Cell Movement; D002540:Cerebral Cortex / Q000002:abnormalities*; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D008297:Male; D009474:Neurons / Q000473:pathology*