Clinical observation on the therapeutic effects of zhongyan-2 recipe in treating 29 HIV-infected and AIDS patients.
OBJECTIVE
To investigate the efficacy of Zhongyan-2 Recipe (ZY-2), a recipe consisting of Chinese herbal medicine.


METHODS
Twenty-nine HIV-infected patients were treated with ZY-2 for 3 months as one treatment course; and viral load, immune function and symptoms-signs were determined before and after treatment.


RESULTS
After treatment, the absolute values of CD4 were elevated in 8 cases, and lowered in 14 cases, 7 cases were not changed; the ratio of CD4/CD8 were elevated in 2 cases, lowered in 1 case, 16 of them were not changed obviously. The CD4 and CD4/CD8 ratio were elevated simultaneously in 2 cases. Neopterin lowered in 4 cases, elevated in 11 cases, and not changed in 1 case. Viral load (VL) was lowered in 6 cases, elevated in 8 cases and not changed in 2 cases. The total effective rate was 42.28% on the basis of comprehensive assessment of VL, immune function, body weight and symptoms-signs.


CONCLUSIONS
ZY-2 is an effective Chinese recipe in treating HIV-infected patients.
Institute of Basic Theory, China Academy of Traditional Chinese Medicine, 18 Beixincang, Dongzhimennei, Beijing 100700.
Jian
J
Wang
Zhimin
Z
Yu
Guoqin
G
Li
Yongxiang
Y
Zhang
Chongfen
C
Guan
Weibo
W
Lu
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy* / Q000276:immunology; D000328:Adult; D016516:CD4-CD8 Ratio; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019798:Neopterin / Q000097:blood; D008517:Phytotherapy; D019562:Viral Load
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D019798:Neopterin