Changing scenario of transfusion-related viral infections.
OBJECTIVE
To study the changing incidence of blood transfusion-related viral infections consequent to compulsory screening of blood and greater awareness of the problem, over the last five years.


METHODS
This is a cross-sectional study carried out at Medical College, Calcutta. Three groups each consisting of 100 subjects were selected for this study. Group A comprised multiple transfused patients who have also received transfusion before 1995. Group B comprised patients who had received transfusions only since 1995. Group C comprised of control patients who have never been transfused. The incidence of HBsAg +ve, anti-HCV +ve and HIV +ve cases were calculated and expressed as percentages and compared using the chi square test.


RESULTS
The incidences of HBsAg +ve and anti-HCV +ve cases in the three groups were 20% and 16% in Group A, 7% and 6% in Group B and 4% and 2% in Group C. The difference between Group A and Group B were statistically significant.


CONCLUSIONS
The incidence of HBsAg and anti-HCV positive cases among the multi-transfused has decreased over the last five years.
Medical College, School of Tropical Medicine, Calcutta.
S C
SC
Hazra
S
S
Chatterjee
S
S
Das Gupta
U
U
Chaudhuri
C K
CK
Jana
D K
DK
Neogi
D000293:Adolescent; D001803:Blood Transfusion / Q000639:trends; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D065227:Transfusion Reaction
D006514:Hepatitis B Surface Antigens