Severe hypoglycaemia associated with a giant solitary fibrous tumor of the pleura.
Solitary fibrous tumors (SFT) of the pleura are a rare neoplasm, with benign biological behaviour. Recurrences are rare, and no distant metastases are described in the literature. SFT can secrete hormone-like substances, responsible for paraneoplastic syndromes. The authors describe a case of severe hypoglycaemia due to insulin-like growth factor II (IGF-2)'s secretion by a giant SFT of the pleura. Hypoglycaemia was controlled by the resection of the tumor. Diagnosis and surgical management of these neoplasms are also discussed.
Department of Thoracic Surgery, University of Torino, San Giovanni Battista Hospital, Italy. pierluigifilosso@tiscalinet.it
P L
PL
Filosso
A
A
Oliaro
O
O
Rena
E
E
Papalia
E
E
Ruffini
M
M
Mancuso
D006801:Humans; D007003:Hypoglycemia / Q000209:etiology*; D007335:Insulin-Like Growth Factor II / Q000378:metabolism; D008297:Male; D008654:Mesothelioma / Q000150:complications* / Q000378:metabolism / Q000601:surgery; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D010997:Pleural Neoplasms / Q000150:complications* / Q000378:metabolism / Q000601:surgery
D007335:Insulin-Like Growth Factor II