Successive pregnancies with delivery of two healthy infants in a couple who was discordant for human immunodeficiency virus infection.
OBJECTIVE
To describe two successive pregnancies resulting in two healthy infants in an HIV-discordant couple who underwent IVF-ICSI.


METHODS
Case report.


METHODS
University-based infertility clinic.


METHODS
A couple seeking fertility treatment in which the male partner was seropositive for HIV-1.


METHODS
Controlled ovarian hyperstimulation and IVF-ET with ICSI.


METHODS
Pregnancy outcome and HIV-1 seroconversion.


RESULTS
The couple delivered two healthy infants on successive pregnancies with use of IVF-ET with ICSI.


CONCLUSIONS
For HIV-discordant couples in which the male partner is seropositive for HIV-1, IVF with ICSI is a viable option.
College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Joseph E
JE
Peña
Jeff
J
Klein
Melvin
M
Thornton
Peter L
PL
Chang
Mark V
MV
Sauer
D000328:Adult; D004624:Embryo Transfer; D005260:Female; D018023:HIV Seronegativity; D006679:HIV Seropositivity; D015497:HIV-1; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D020554:Sperm Injections, Intracytoplasmic