Quantification of spinal cord atrophy from magnetic resonance images via a B-spline active surface model.
A method is presented that aims at segmenting and measuring the surface of the spinal cord from MR images in order to detect and quantify atrophy. A semiautomatic segmentation with very little intervention from an operator is proposed. It is based on the optimization of a B-spline active surface. The method allows for the computation of orthogonal cross-sections at any level along the cord, from which measurements are derived, such as cross-sectional area or curvature. An evaluation of the accuracy and reproducibility of the method is presented.
Coulon
O
O
Department of Computer Science, University College London, London, UK. Olivier.Coulon@esil.univ-mrs.fr
Hickman
S J
SJ
Parker
G J
GJ
Barker
G J
GJ
Miller
D H
DH
Arridge
S R
SR
D001284:Atrophy / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009103:Multiple Sclerosis / Q000150:complications; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D013116:Spinal Cord / Q000473:pathology*