Comparison of open carpal tunnel release and local steroid treatment outcomes in idiopathic carpal tunnel syndrome.
To compare the efficacy of local steroid injection and open carpal tunnel release, a symptom and functional status questionnaire (Boston Questionnaire) and sensory and motor nerve conduction studies were performed in 90 patients with electrophysiologically proven idiopathic carpal tunnel syndrome, of whom 44 were treated surgically and 46 by two-dose steroid injection. Electrophysiologic studies and the Boston Questionnaire were applied before and at the 3rd and 6th months after treatment. Both groups showed significant improvement at first follow-up. The surgically treated group showed a significant and further improvement of symptoms and conduction values between the 3rd- and 6th-month evaluations, whereas no significant change was observed in the patient group treated by steroid injection. By the end of follow-up, 5% of the hands in the open carpal tunnel release (OCTR) group and 13% of the hands in the local steroid injection (LSIG) group showed electrophysiological worsening, and 5% of the hands in the OCTR group and 22% of the hands in the LSIG group showed symptomatic worsening. Our results show that steroid injection provides an improvement comparable with that from surgical release of the median nerve at a 3-month interval. However, this improvement is not long-lasting.
Demirci
Serpil
S
Department of Neurology, Suleyman Demirel University School of Medicine, Isparta, Turkey. serpildemirci@hotmail.com
Kutluhan
Suleyman
S
Koyuncuoglu
H Rifat
HR
Kerman
Memduh
M
Heybeli
Nurettin
N
Akkuş
Selami
S
Akhan
Galip
G
D000328:Adult; D000368:Aged; D002349:Carpal Tunnel Syndrome / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery*; D004185:Disability Evaluation; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000187:drug effects* / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D009431:Neural Conduction / Q000187:drug effects / Q000502:physiology; D019637:Orthopedic Procedures / Q000009:adverse effects / Q000706:statistics & numerical data*; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D020127:Recovery of Function / Q000187:drug effects; D012008:Recurrence; D013256:Steroids / Q000009:adverse effects / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014955:Wrist Joint / Q000187:drug effects / Q000503:physiopathology / Q000601:surgery
D013256:Steroids