Three new phlegmariurine B type lycopodium alkaloids from Huperzia serrata.
Phlegmariurine B (1), a known alkaloid, along with three new analogous compounds, 2alpha-hydroxyphlegmariurine B (2), 2-oxoyphlegmariurine B (3) and 11-oxophlegmariurine B (4), were isolated from the CHCl3 fraction of total alkaloids of whole plant of the Chinese medicinal herb Huperzia serrata. Their structures were elucidated by spectral analysis.
State Key Laboratory of New Drug Research, Shanghai Institute of Material Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.
Chang-Heng
CH
Tan
Guo-Fu
GF
Chen
Xiao-Qiang
XQ
Ma
Shan-Hao
SH
Jiang
Da-Yuan
DY
Zhu
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D032501:Huperzia; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification
D000470:Alkaloids; D010936:Plant Extracts; C469768:phlegmariurine B