Conjugate addition of radicals generated from diacyloxyiodobenzenes to dehydroamino acid derivatives; a synthesis of diaminopimelic acid analogues.
Radical decomposition of bis((2S)-N-benzyloxycarbonyl-2-aminopentan-5-carboxy-1-methyl ester)iodobenzene followed by decarboxylation and subsequent conjugate addition with a series of selectively protected dehydroamino acids leads to new analogues of diaminopimelic acid.
Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2G2.
Andrew
A
Sutherland
John C
JC
Vederas