Transcriptomics and proteomics: tools for the identification of novel drug targets and vaccine candidates for tuberculosis.
The availability of the complete genome sequence of Mycobacterium tuberculosis has revolutionised many areas of tuberculosis research and facilitated functional genomics studies. Most notably, transcriptomics and proteomics have become important tools in gaining increased understanding of the biology of M. tuberculosis and offer the promise of being able to deliver novel drug targets and vaccine candidates.
Betts
Joanna C
JC
GlaxoSmithKline Research and Development, Stevenage, Herts, United Kingdom. jb75084@gsk.com
D015180:Electrophoresis, Gel, Two-Dimensional; D016678:Genome; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D020543:Proteome; D012984:Software; D014376:Tuberculosis / Q000188:drug therapy* / Q000235:genetics*; D014612:Vaccines
D020543:Proteome; D014612:Vaccines