Coronary artery stents: evaluating new designs for contemporary percutaneous intervention.
Intracoronary stents have markedly improved the short- and long-term safety and efficacy of percutaneous coronary intervention by improving acute gains in luminal dimensions, decreasing abrupt vessel occlusion, and reducing restenosis. At present, nearly 90% of all coronary interventions involve stenting. A variety of advances in stent technology and design have expanded the clinical application of stenting to include complex coronary lesions, multivessel disease, and small-diameter vessels. In addition, the development of stents as drug delivery systems for antithrombotic or antiproliferative agents has the potential to expand the role of coronary stenting, and early clinical experience appears promising. The purpose of this review is to describe recent developments in stent design, examine the results of clinical trials of contemporary stents, and present future directions for investigation of new stent technologies.
Division of Cardiology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina 27710, USA. kandz002@onyx.dcri.duke.edu
David E
DE
Kandzari
James E
JE
Tcheng
James P
JP
Zidar
D020341:Absorbable Implants; D020099:Coated Materials, Biocompatible; D023921:Coronary Stenosis / Q000628:therapy*; D016503:Drug Delivery Systems; D004867:Equipment Design; D006801:Humans; D013193:Stainless Steel; D015607:Stents
D020099:Coated Materials, Biocompatible; D013193:Stainless Steel