Genetic detection and isolation of crimean-congo hemorrhagic fever virus, Kosovo, Yugoslavia.
Crimean-Congo hemorrhagic fever virus (C-CHFV) strains were isolated from a fatal case and the attending physician in Kosovo, Yugoslavia. Early, rapid diagnosis of the disease was achieved by reverse transcription-polymerase chain reaction. The physician was successfully treated with oral ribavirin. These cases yielded the first genetically studied C-CHFV human isolates in the Balkans.
Papa
Anna
A
Aristotelian University of Thessaloniki, Thessaloniki, Greece. annap@med.auth.gr
Bozovi
Bojana
B
Pavlidou
Vassiliki
V
Papadimitriou
Evangelia
E
Pelemis
Mijomir
M
Antoniadis
Aantonis
A
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D005260:Female; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000235:genetics* / Q000302:isolation & purification*; D006479:Hemorrhagic Fever, Crimean / Q000188:drug therapy* / Q000821:virology*; D006801:Humans; D008297:Male; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011233:Precipitin Tests; D012367:RNA, Viral / Q000235:genetics; D012254:Ribavirin / Q000627:therapeutic use; D015022:Yugoslavia
D000998:Antiviral Agents; D012367:RNA, Viral; D012254:Ribavirin