Hypersensitivity pneumonitis induced by the spore of Pleurotus Eryngii (Eringi).
We reported the first case of hypersensitivity pneumonitis (HP) by an edible mushroom, Pleurotus Eryngii (Eringi). A 54-year-old woman had worked in a Bunashimeji mushroom factory for 42 months, and she moved to a new factory producing Eringi. Two months after, she was found to have HP by the spore of Eringi. Although no radiological finding was detected 6 months before the onset of HP, serum surfactant protein D (SP-D) had been elevated. We speculated that type II pneumocyte activation might prepare the ground for HP during the former exposure to Bunashimeji, and serum SP-D levels might reflect their conditions.
Toyohiro
T
Saikai
Hiroshi
H
Tanaka
Masaru
M
Fuji
Hiroyuki
H
Sugawara
Isao
I
Takeya
Kazunori
K
Tsunematsu
Shosaku
S
Abe
D000382:Agricultural Workers' Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D018893:Bronchoalveolar Lavage; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D008875:Middle Aged; D020076:Pleurotus / Q000276:immunology* / Q000302:isolation & purification; D011239:Prednisolone / Q000627:therapeutic use; D037663:Pulmonary Surfactant-Associated Protein D / Q000097:blood / Q000276:immunology; D013172:Spores, Fungal / Q000276:immunology* / Q000302:isolation & purification; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D015415:Biomarkers; D037663:Pulmonary Surfactant-Associated Protein D; D011239:Prednisolone