Keratopathy from congenital syphilis.
OBJECTIVE
Therapeutic decision-making in syphilitic corneal disease is discussed after seeing a patient with keratopathy from congenital syphilis.


METHODS
Case report and review of the literature.


RESULTS
Laboratory evaluation of our patient revealed a nonreactive serum rapid plasma reagin (RPR) test and a positive microhemagglutination assay-Treponema pallidum (MHA-TP) test.


CONCLUSIONS
Any patient with residual interstitial keratopathy, especially if bilateral, should be suspected to have congenital syphilis if the patient or parents were ever treated for a sexually transmitted disease, if stigmata of congenital syphilis are present, or if childhood ocular inflammation occurred.
Hariprasad
Seenu M
SM
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX 77030, USA.
Moon
Suk Jin
SJ
Allen
Richard C
RC
Wilhelmus
Kirk R
KR
D000368:Aged; D002908:Chronic Disease; D006801:Humans; D007634:Keratitis / Q000209:etiology*; D008297:Male; D013590:Syphilis, Congenital / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy