Norditerpenoid alkaloids from Consolida orientalis and complete 1H and 13C NMR signal assignments of some lycoctonine-type alkaloids.
A new norditerpene alkaloid was isolated, 18-demethylpubescenine (1), in addition to four known compounds, 14-demethyltuguaconitine (2), takaosamine (3), gigactonine (4), and delcosine (5), from fresh, whole plants of Consolida orientalis. The structure of 1 was established by spectroscopic methods, including various 2D NMR techniques and HRESIMS. As a result of a detailed NMR study, complete 1H NMR chemical shift assignments for alkaloids 1-5 are presented herein, and some 13C NMR signal assignments for 2-4 have been revised.
Hohmann
Judit
J
Department of Pharmacognosy, University of Szeged, H-6720 Szeged, Hungary. hohmann@pharm-szote.u-szeged.hu
Forgo
Peter
P
Hajdú
Zsuzsanna
Z
Varga
Erzsébet
E
Máthé
Imre
I
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D006814:Hungary; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
C465913:14-demethyltuguaconitine; C465912:18-demethylpubescenine; D000470:Alkaloids; D004224:Diterpenes; C465915:gigactonine; C465914:takaosamine