Treatment outcome, body image, and sexual functioning after orchiectomy and radiotherapy for Stage I-II testicular seminoma.
OBJECTIVE
Orchiectomy followed by infradiaphragmatic irradiation is the standard treatment for Stage I-II testicular seminoma in The Netherlands. Because body image and sexual functioning can be affected by treatment, a retrospective study was carried out to assess treatment outcome, body image, and changes in sexuality after orchiectomy and radiotherapy.


METHODS
The medical charts of 166 patients with Stage I-II testicular seminoma were reviewed. A questionnaire on body image and current sexual functioning regarding the frequency and quality of erections, sexual activity, significance of sex, and changes in sexuality was sent to 157 patients (at a mean of 51 months after treatment).


RESULTS
Seventy-eight percent (n = 123, mean age 42 years) completed the questionnaire. During irradiation, almost half of patients experienced nausea and 19% nausea and vomiting. Only 3 patients had disease relapse. After treatment, about 20% reported less interest and pleasure in sex and less sexual activity. Interest in sex, erectile difficulties, and satisfaction with sexual life did not differ from age-matched healthy controls. At the time of the survey, 17% of patients had erectile difficulties, a figure that was significantly higher than before treatment, but which correlated also with age. Twenty percent expressed concerns about fertility, and 52% found their body had changed after treatment. Cancer treatment had negatively influenced sexual life in 32% of the patients.


CONCLUSIONS
Orchiectomy with radiotherapy is an effective and well-tolerated treatment for Stage I-II testicular seminoma. Treatment-induced changes in body image and concerns about fertility were detected, but the sexual problems encountered did not seem to differ from those of healthy controls, although baseline data are lacking.
Department of Radiation Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands. incrocci@rtdh.azr.nl
Luca
L
Incrocci
Wim C J
WC
Hop
Arendjan
A
Wijnmaalen
A Koos
AK
Slob
D000293:Adolescent; D000328:Adult; D000368:Aged; D001828:Body Image; D006801:Humans; D007989:Libido / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy / Q000009:adverse effects* / Q000523:psychology*; D010410:Penile Erection; D012189:Retrospective Studies; D018239:Seminoma / Q000532:radiotherapy* / Q000601:surgery*; D012725:Sexual Behavior; D019968:Sexual and Gender Disorders; D011795:Surveys and Questionnaires; D013736:Testicular Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome