Gadobutrol: an alternative contrast agent for digital subtraction dacryocystography.
We report the application of gadobutrol as a contrast medium for digital subtraction dacryocystography (DS-DCG) in patients with known allergy to iodinated contrast agent. Gadobutrol has the double gadolinium concentration (1.0 mmol/ml) of other gadolinium-based contrast agents. Quality of the DS-DCG images obtained with gadobutrol was comparable to DS-DCG images obtained with iodinated contrast medium. Radiodensity measurements using a micro-CT scanner confirmed a high radiodensity of gadobutrol which was comparable to the radiodensity of iopentol with a iodine concentration of 250 mg/ml and only approximately 20% lower than the radiodensity of iopentol with a concentration of 300 mg/l. Gadobutrol is a well-suited substitute for DS-DCG in patients with allergy to iodinated contrast agents.
Priebe
M
M
Department of Diagnostic Radiology, Christian-Albrechts-University of Kiel, Arnold-Heller-Strasse 9, 24105 Kiel, Germany. m.priebe@t-online.de
Mohr
A
A
Brossmann
J
J
Heller
M
M
Frahm
C
C
D000368:Aged; D015901:Angiography, Digital Subtraction; D003287:Contrast Media; D005260:Female; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis*; D007767:Lacrimal Duct Obstruction / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds
D003287:Contrast Media; D009942:Organometallic Compounds; C090600:gadobutrol