Modification of radiation-induced changes in the reproductive system of male rats with sodium succinate.
We studied the effects of sodium succinate on the reproductive system and blood leukocyte count in rats 30 and 60 days after fractionated irradiation in a dose of 1 Gy. Sodium succinate in concentrations of 0.2 and 0.5% was given ad libitum with water before (1 week) and during irradiation (5 days). The preparation promoted morphofunctional recovery of the testes and epididymides and restored the count of peripheral blood leukocytes.
Vereshchako
G G
GG
Institute of Radiobiology, Belarussian Academy of Sciences, Minsk.
Khodosovskaya
A M
AM
Artemenko
O V
OV
Konoplya
E F
EF
D000818:Animals; D005837:Genitalia, Male / Q000187:drug effects* / Q000201:enzymology / Q000528:radiation effects*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D011833:Radiation Injuries, Experimental / Q000188:drug therapy*; D051381:Rats; D013076:Sperm Count; D019802:Succinic Acid / Q000494:pharmacology / Q000627:therapeutic use*
D019802:Succinic Acid; D007770:L-Lactate Dehydrogenase