1,3-Dibromo-5,5-dimethylhydantoin (DBH) as oxidant and precipitant for drug identification according to PH. EUR Analytical methods of pharmacopoeias with DBH in respect of environmental and economical concern, Part 15(1).
Elemental bromine serves as oxidant for the identification of propylthiouracil, 2-thiouracil and sulphur according to PH. EUR. 2002. Phenol is identified according to PH. EUR. 2002 with bromine water as the sparingly water-soluble 2,4,4,6-tetrabromo-2,5-cyclohexadiene-1-one. These tests can be performed better using 1,3-dibromo-5,5-dimethylhydantoin (DBH).
Hilp
M
M
Institut für Pharmazeutische Chemie, Philipps-Universität, Marburg, Germany. Hilp@mailer.uni-marburg.de
D001966:Bromine / Q000737:chemistry; D005060:Europe; D006827:Hydantoins / Q000737:chemistry*; D007202:Indicators and Reagents; D016877:Oxidants / Q000737:chemistry*; D010602:Pharmacopoeias as Topic; D019800:Phenol / Q000032:analysis; D011441:Propylthiouracil / Q000032:analysis; D013455:Sulfur / Q000032:analysis; D013889:Thiouracil / Q000032:analysis
D006827:Hydantoins; D007202:Indicators and Reagents; D016877:Oxidants; D019800:Phenol; D013889:Thiouracil; D013455:Sulfur; D011441:Propylthiouracil; D001966:Bromine; C056578:1,3-dibromo-5,5-dimethylhydantoin