Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer.
Turk
Vito
V
Department of Biochemistry and Molecular Biology, J. Stefan Institute, Jamova 39, SI-1000 Ljubljana, Slovenia. vito.turk@ijs.si
Turk
Boris
B
Guncar
Gregor
G
Turk
Dusan
D
Kos
Janko
J
D017951:Antigen Presentation; D000941:Antigens / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000494:pharmacology; D002403:Cathepsins / Q000737:chemistry / Q000378:metabolism*; D015891:Cystatins / Q000378:metabolism; D003546:Cysteine Endopeptidases / Q000378:metabolism; D006801:Humans; D008247:Lysosomes / Q000201:enzymology / Q000378:metabolism*; D008285:Major Histocompatibility Complex; D008958:Models, Molecular; D009361:Neoplasm Invasiveness; D009369:Neoplasms / Q000276:immunology* / Q000378:metabolism; D009389:Neovascularization, Pathologic; D011487:Protein Conformation; D013379:Substrate Specificity; D013997:Time Factors
D000941:Antigens; D000970:Antineoplastic Agents; D015891:Cystatins; D002403:Cathepsins; D003546:Cysteine Endopeptidases