Hydroxy-substituted oligopyridine dicarboxamide helical foldamers.
As shown by X-ray diffraction and NMR studies, short oligopyridine dicarboxamides bearing benzyloxy, hydroxy and hydroxylate moieties adopt very robust single helical conformations, even in water.
Institut Européen de Chimie et Biologie, 16 av. Pey Berland, 33607 Pessac, France. i.huc@iecb-polytechnique.u-bordeaux.fr
Ivan
I
Huc
Victor
V
Maurizot
Heinz
H
Gornitzka
Jean-Michel
JM
Léger
D006900:Hydroxylation; D008968:Molecular Conformation; D018716:Molecular Mimicry; D009757:Nylons / Q000737:chemistry*; D009842:Oligopeptides / Q000737:chemistry; D017433:Protein Structure, Secondary; D011725:Pyridines / Q000737:chemistry*
D009757:Nylons; D009842:Oligopeptides; D011725:Pyridines; C023666:pyridine