Solid supported fluoronitroaryl triazenes as immobilized and convertible Sanger reagents--synthesis and SNAr reactions towards a novel preparation of 1-alkyl-5-nitro-1H-benzotriazoles.
Synthesis of novel fluoronitroaryl triazenes in liquid phase and on solid support have been described; mild displacement of the fluoride ion with various nucleophiles provides access to substituted arenes which in turn can be cleaved to provide a unique access to 1-alkyl-5-nitro-1H-benzotriazole.
RWTH Aachen, Institut für Organische Chemie, Professor-Pirlet-Str. 1, D-52074 Aachen, Germany.
Matthias E P
ME
Lormann
Catherine H
CH
Walker
Mazen
M
Es-Sayed
Stefan
S
Bräse