Alternative splicing of LYT1 transcripts in Trypanosoma cruzi.
As a result of alternative trans splicing, three distinct LYT1 mRNAs are produced in Trypanosoma cruzi, two encoding the full-length LYT1 protein and the third encoding a truncated LYT1 protein lacking a possible signal sequence. Analysis of the three mRNAs in different developmental forms of the parasite revealed that the alternative processing events were regulated differently during the parasite life cycle.
Departamento de Biomedicina Molecular, Centro de Investigación y de Estudios Avanzados del IPN, México, D.F., México.
Rebeca
R
Manning-Cela
Antonio
A
González
John
J
Swindle
D017398:Alternative Splicing; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D016054:DNA, Protozoan; D005091:Exons; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D015800:Protozoan Proteins / Q000235:genetics*; D012333:RNA, Messenger; D016053:RNA, Protozoan; D020040:Trans-Splicing; D014349:Trypanosoma cruzi / Q000235:genetics*
D016054:DNA, Protozoan; C429281:LYT1 protein, Trypanosoma cruzi; D015800:Protozoan Proteins; D012333:RNA, Messenger; D016053:RNA, Protozoan