Spatial distribution of mDLG6 mRNA in embryonic and adult mouse brain.
We have isolated mouse DLG6 (mDLG6) cDNA clones by RT-PCR and then by using the RT-PCR products to screen a mouse brain cDNA library. The deduced amino acid sequence of mDLG6 shows 79.2% and 82.7% overall identity to human (hDLG6) and rat DLG6 (rDLG6), respectively. In situ hybridization revealed that mDLG6 mRNA is predominantly expressed in embryonic and adult brain.
Inagaki
Hidetoshi
H
Molecular Neurophysiology Group, Neuroscience Research Institute, National Institute of Advanced Industrial Science and Technology, 1-1 Higashi, Tukuba, Ibaragi, 305-8566, Japan. hinagaki@aist.go.jp
Tanaka
Kimiko
K
Takada
Mayuko
M
Maeda
Sumio
S
Ichihara
Shigeyuki
S
Saito
Takao
T
D000818:Animals; D001921:Brain / Q000166:cytology / Q000196:embryology* / Q000378:metabolism*; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000032:analysis / Q000235:genetics; D029721:Drosophila Proteins / Q000235:genetics / Q000302:isolation & purification*; D005333:Fetus; D018507:Gene Expression Regulation, Developmental / Q000235:genetics*; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000302:isolation & purification*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000302:isolation & purification*
C570396:DLG6 protein, mouse; D018076:DNA, Complementary; D029721:Drosophila Proteins; D009419:Nerve Tissue Proteins; D012333:RNA, Messenger; D025521:Tumor Suppressor Proteins; C070350:dlg1 protein, Drosophila