Delayed consequences of protein deficiency during lactation for the development of enzyme systems of digestive and nondigestive organs in offspring.
Suboptimal protein nutrition during lactation has a negative impact on the digestive function of the small intestine and trophic barrier functions of the large intestine, liver, and kidneys due to significant enzyme deficiency (disaccharidase, peptidase, alkaline phosphatase) in 6-month-old offspring. Changes in enzyme activity in digestive and nondigestive organs play an important role in metabolic disorders promoting the development of "risk diseases" and reducing lifespan.
Timofeeva
N M
NM
I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg.
Gordova
L A
LA
Egorova
V V
VV
Nikitina
A A
AA
D000818:Animals; D000831:Animals, Newborn; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D007422:Intestines / Q000201:enzymology*; D007668:Kidney / Q000201:enzymology*; D007774:Lactation; D008099:Liver / Q000201:enzymology*; D008297:Male; D018811:Maternal Exposure; D011247:Pregnancy; D051381:Rats
D004044:Dietary Proteins