Bioinformatics methods for the analysis of expression arrays: data clustering and information extraction.
Expression arrays facilitate the monitoring of changes in the expression patterns of large collections of genes. The analysis of expression array data has become a computationally-intensive task that requires the development of bioinformatics technology for a number of key stages in the process, such as image analysis, database storage, gene clustering and information extraction. Here, we review the current trends in each of these areas, with particular emphasis on the development of the related technology being carried out within our groups.
ALMA Bioinformatics, S.L., Spain.
Javier
J
Tamames
Dominic
D
Clark
Javier
J
Herrero
Joaquín
J
Dopazo
Christian
C
Blaschke
José M
JM
Fernández
Juan C
JC
Oliveros
Alfonso
A
Valencia
D000043:Abstracting and Indexing / Q000379:methods; D016000:Cluster Analysis; D003628:Database Management Systems; D030541:Databases, Genetic; D015870:Gene Expression; D020869:Gene Expression Profiling / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D016239:MEDLINE; D009317:National Library of Medicine (U.S.); D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D014481:United States