Insect antifeedant activity of tetranortriterpenoids from the Rutales. A perusal of structural relations.
Structure-related insect antifeedant relationship of 56 limonoids (both natural and modified) from the plants belonging to the order Rutales was attempted considering substitution patterns, oxidation states, and hydrophobicity, as well as distant geometry derived through conformational analysis on molecular modeling. Orientation of the furan and hydroxylation at specific carbon sites have been shown to influence the antifeedancy against the fall armyworm, Spodoptera litura.
Centre for Natural Products, SPIC Science Foundation, 64, Mount Road, Guindy, Chennai 600 032, India. sureshgovind55@hotmail.com
G
G
Suresh
Geetha
G
Gopalakrishnan
S Daniel
SD
Wesley
N D
ND
Pradeep Singh
R
R
Malathi
S S
SS
Rajan
D000818:Animals; D004435:Eating / Q000187:drug effects; D006110:Grasshoppers / Q000502:physiology*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D036701:Limonins; D015394:Molecular Structure; D027821:Rutaceae / Q000737:chemistry*; D018411:Spodoptera / Q000502:physiology; D013329:Structure-Activity Relationship; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
D007306:Insecticides; D036701:Limonins; D014315:Triterpenes; C010329:azadirachtin