Stress inhibits seasonal and FSH-induced ovarian recrudescence in the lizard,Mabuya carinata.
Stressors (handling, chasing, and noise) applied randomly five times per day for one month to lizards during the recrudescence phase of the ovarian cycle caused a significant reduction in mean number of oocytes and primordial follicles when compared to those of controls. Further, vitellogenic follicles were absent in the ovary of lizards subjected to stressors. Administration of bovine FSH during post-breeding regression phase of the ovarian cycle induced ovarian recrudescence as shown by significant increases in the mean number of oogonia, oocytes, and primordial follicles compared to controls, as well as vitellogenic growth of follicles. However, lizards treated with FSH and exposed to stressors did not exhibit ovarian recrudescence. Furthermore, FSH administration during the post-breeding regression phase caused a significant increase in serum levels of estradiol compared to controls, which was accompanied by significant increases in the relative weight of the liver and oviduct, as well as vitellogenic growth of follicles. Despite administration of FSH to lizards subjected to stressors, there was neither any increase in serum levels of estradiol and weight of the liver nor vitellogenic growth of follicles. The results indicate that repeated application of stressors inhibits vitellogenic growth of follicles by suppression of steroidogenic activity in M. carinata. This is the first report revealing that the ovary does not respond to gonadotrophin treatment under stressful conditions in reptiles.
Ganesh
C B
CB
Department of Studies in Zoology, University of Mysore, Manasagangotri, Mysore-570 006, India.
Yajurvedi
H N
HN
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002417:Cattle; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects; D008116:Lizards / Q000502:physiology*; D008597:Menstrual Cycle / Q000187:drug effects*; D009865:Oocytes / Q000166:cytology / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D006080:Ovarian Follicle / Q000187:drug effects; D010053:Ovary / Q000166:cytology / Q000187:drug effects* / Q000502:physiology*; D010057:Oviducts / Q000187:drug effects / Q000502:physiology; D012098:Reproduction / Q000187:drug effects; D012621:Seasons; D013312:Stress, Physiological / Q000503:physiopathology*
D004958:Estradiol; D005640:Follicle Stimulating Hormone