BF3.OEt2-mediated cycloaddition of O-tert-butyldimethylsilyloximes having olefin moieties: intramolecular cycloaddition of N-borano-nitrones.
Treatment of O-tert-butyldimethylsilyloximes having olefin moieties in the molecules with BF3.OEt2 results in efficient generation of N-borano-nitrones, which undergo intramolecular cycloaddition at room temperature to afford N-nonsubstituted cycloadducts after work-up.
Faculty of Pharmaceutical Sciences, Kanazawa University, Takara-machi, Kanazawa 920-0934, Japan. tamura@mail.p.kanazawa-u.ac.jp
Osamu
O
Tamura
Takahiro
T
Mitsuya
Hiroyuki
H
Ishibashi