[Enzymatic activity of some tissues and blood serum from animals and humans exposed to microwaves and hypothesis on the possible role of free radical processes in the nonlinear effects and modification of emotional behavior of animals].
The dependence of activities of actomyosin ATPase, alkaline phosphatase, aspartataminotranspherase, monoaminoxidase and that of affective rat behavior on frequency of modulation of microwaves (0.8-10 microW/cm2) was explored at short-time actions. Series of nonlinear phenomenons, inexplicable from positions of the energy approaches are revealed, The working hypothesis explaining opportunity of high performance of weak and super-weak microwaves and other revealed phenomena by resonance interaction of such electromagnetic radiofrequency radiation with paramagnetic molecules of biological tissues was proposed. This resonance interaction activate free radicals and initiate auto-supporting and auto-intensifying of chain chemical reactions. The spontaneous autocatalytic oxidation of catecholamines enlarges a common pool of free radicals, capable to participate in such enhanced generating. The protective role of monoaminoxidase is postulated. Monoaminoxidase is basically located on an outer surface of mitochondrias and it is deaminating monoamines. The deaminating prevents penetration of catecholamines inside of mitochondrias and their quinoid oxidation there with formation of free-radical semi-quinons, capable to destroy system of ATP synthesis. These inferences are obliquely confirmed by the experimentally revealed correlation between activity of monoaminoxidase and integrative activity of the rat brain.
Akoev
I G
IG
Institute of Cell Biophysics, Russian Academy of Science, Pushchino, 142290 Russia. admin@icb.psn.ru
Pashovkina
M S
MS
Dolgacheva
L P
LP
Semenova
T P
TP
Kalmykov
V L
VL
D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood / Q000378:metabolism*; D001522:Behavior, Animal / Q000528:radiation effects*; D005609:Free Radicals; D006801:Humans; D008872:Microwaves; D008995:Monoamine Oxidase / Q000097:blood / Q000378:metabolism*; D009218:Myosins / Q000097:blood / Q000378:metabolism*; D051381:Rats; D013315:Stress, Psychological
D005609:Free Radicals; D008995:Monoamine Oxidase; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase; D009218:Myosins