Discovery of a novel synthetic phosphatase from a bead-bound combinatorial library.
Using split/pool encoded synthesis and a colorimetric catalysis assay, a number of synthetic phosphatase catalysts were developed.
Danek
Shelley C
SC
Department of Chemistry, Venable and Kenan Laboratories, UNC Chapel Hill, Chapel Hill, NC 27516, USA.
Queffelec
Jerome
J
Morken
James P
JP
D020650:Combinatorial Chemistry Techniques; D006868:Hydrolysis; D008958:Models, Molecular; D018716:Molecular Mimicry; D010744:Phosphoric Monoester Hydrolases / Q000138:chemical synthesis* / Q000737:chemistry; D012117:Resins, Synthetic
D012117:Resins, Synthetic; D010744:Phosphoric Monoester Hydrolases