The involvement of RNA in ribosome function.
The ribosome is a particle made of RNA and protein that is found in abundance in all cells that are actively making protein. It catalyses the messenger RNA-directed synthesis of proteins. Recent structural work has demonstrated a profound involvement of the ribosome's RNA component in all aspects of its function, supporting the hypothesis that proteins were added to the ribosome late in its evolution.
Department of Molecular Biophysics and Biochemistry, Yale University, PO Box 208107, New Haven, Connecticut 06520-8107, USA. peter.moore@yale.edu
Peter B
PB
Moore
Thomas A
TA
Steitz
D001665:Binding Sites; D019143:Evolution, Molecular; D008956:Models, Chemical; D008958:Models, Molecular; D012335:RNA, Ribosomal / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D012343:RNA, Transfer / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012270:Ribosomes / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*
D012335:RNA, Ribosomal; D012343:RNA, Transfer