[The photodynamic inactivation of Candida guilliermondii in the presence of photodithazine].
Photodithazine, a glucosamine salt of chlorin e6, enhanced the inactivation of Candida guilliermondii cells by visible light. The sensitizing effect of photodithazine was found to be related to free or cell surface-bound molecules of this dye. Sodium azide (a singlet oxygen quencher) and propyl gallate (an inhibitor of lipid peroxidation) protected yeast cells from the photodithazine-enhanced photoinactivation.
Department of Biophysics, Faculty of Biology, Moscow State University, Vorob'evy gory, Moscow, 119899 Russia. marstr@biophys.msu.ru
M G
MG
Strakhovskaia
N S
NS
Belenikina
E V
EV
Ivanova
Iu K
IuK
Chemeris
E F
EF
Stranadko
D000975:Antioxidants / Q000494:pharmacology; D002175:Candida / Q000187:drug effects* / Q000528:radiation effects; D002735:Chlorophyllides; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005944:Glucosamine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D008027:Light; D017319:Photosensitizing Agents / Q000494:pharmacology*; D011166:Porphyrins / Q000737:chemistry / Q000494:pharmacology*; D011435:Propyl Gallate / Q000494:pharmacology; D019810:Sodium Azide / Q000494:pharmacology
D000975:Antioxidants; D002735:Chlorophyllides; D004791:Enzyme Inhibitors; D017319:Photosensitizing Agents; D011166:Porphyrins; C062985:phytochlorin; D011435:Propyl Gallate; D019810:Sodium Azide; D005944:Glucosamine