Comparative evaluation of three alpha-hydroxycarboxylic acids for the separation of lanthanides by dynamically modified reversed-phase high-performance liquid chromatography.
The resolution for the three homologues of alpha-hydroxycarboxylic acids viz. lactic acid, alpha-hydroxyisobutyric acid (alpha-HIBA) and alpha-hydroxy-alpha-methylbutyric acid (alpha-H-alpha-MBA), was compared for the individual separation of 14 lanthanide elements under identical experimental conditions. Alpha-HIBA was found to be the best for separation of heavier lanthanides (Tb to Lu) while alpha-H-alpha-MBA led to a better separation for lighter lanthanides (La to Eu). All the 14 lanthanides were separated by gradient HPLC employing both alpha-HIBA and alpha-H-alpha-MBA so that there was reasonable resolution among all the peaks and the separation was completed in a short time.
Fuel Chemistry Division, Bhabha Atomic Research Centre, Mumbai, India.
Narendra M
NM
Raut
P G
PG
Jaison
Suresh K
SK
Aggarwal
D002264:Carboxylic Acids / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D028581:Lanthanoid Series Elements / Q000302:isolation & purification*
D002264:Carboxylic Acids; D028581:Lanthanoid Series Elements