Prolonged shedding of rotavirus in a geriatric inpatient.
This study concerns a nosocomial rotaviral infection of a geriatric patient with clinical symptoms of acute gastroenteritis. The virological diagnosis was based on the detection of rotaviral antigens using a Rota kit, viral genome RNA by reverse transcription-polymerase chain reaction method, and viral particles by electron microscopy in the stool samples. Prolonged rotaviral shedding was suggested to be due to impaired natural killer cell activity, possibly together with deficiency of specific local immune response of the patient.
Mori
Isamu
I
Pediatrics Department, Koyo Hospital, Fukui, Japan.
Matsumoto
Kazuo
K
Sugimoto
Kazunori
K
Kimura
Makiko
M
Daimon
Nagomu
N
Yokochi
Takashi
T
Kimura
Yoshinobu
Y
D000368:Aged; D000956:Antigens, Viral / Q000032:analysis / Q000235:genetics; D003428:Cross Infection / Q000635:transmission / Q000821:virology*; D005243:Feces / Q000821:virology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D016867:Immunocompromised Host; D012401:Rotavirus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification* / Q000502:physiology*; D012400:Rotavirus Infections / Q000635:transmission / Q000821:virology*; D013997:Time Factors; D017201:Virus Shedding
D000956:Antigens, Viral