Low-molecular-weight heparin for vertebral artery dissection.
A case of vertebral artery dissection and consequent basilar artery thrombosis in a 6-year-old patient is reported. The patient was treated with subcutaneous low-molecular-weight heparin at therapeutic doses (enoxaparin, 100 IU/kg twice daily) for 3 weeks, then reduced to 2,000 IU/day for 3 more weeks. After this time a magnetic resonance angiogram was obtained that showed complete recanalization of the left basilar artery. Enoxaparin proved to be a safe and useful therapy for thrombosis accompanying vertebral artery dissection.
Marietta
Marco
M
Department of Medical Sciences, University of Modena and Reggio Emilia, Italy. marietta@unimo.it
Bertesi
Marcello
M
Rozzi
Nino
N
Cano
Maria Carmen
MC
Vallone
Stefano
S
Cappi
Cinzia
C
Pozzi
Samantha
S
Torelli
Giuseppe
G
D002648:Child; D017984:Enoxaparin / Q000008:administration & dosage; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome; D020217:Vertebral Artery Dissection / Q000150:complications / Q000188:drug therapy*
D017984:Enoxaparin; D006495:Heparin, Low-Molecular-Weight