Accumulation of tributyltin in the blood of fish: its application for monitoring in the marine environment.
Accumulation of tributyltin (TBT) in serum, liver, muscle, and gill of olive flounder (Paralichthys olivaceus) was examined in a 30-d static-renewal exposure. Tributyltin accumulated rapidly in the serum of the olive flounder and to a greater extent than in the other tissues. The accumulated TBT concentrations in tissues were in the order of serum > gill > liver > muscle on a dry-weight basis. Tributyltin also was detected in the serum of feral fine-spotted flounder, Pleuronichthys cornutus, collected from the coastal area. The mean TBT concentration in serum (2,470 ng Sn/g) of the fine-spotted flounder was about 40 times higher than that in the liver (60 ng Sn/g) and 200 times higher than that in the muscle (27 ng Sn/g) on a dry-weight basis. The TBT concentrations in serum and sediment demonstrated a positive correlation. The percent TBT composition to total butyltin was much higher in the serum (71%) than in the other tissues and sediment (<47%). These results suggest that the analysis of fish blood serum could be a useful tool for monitoring exposure to TBT in the marine environment.
Marine Environment and Climate Change Laboratory, Korea Ocean Research and Development Institute, Seoul. wjshim@kordi.re.kr
Won Joon
WJ
Shim
Joong Kyun
JK
Jeon
Jae Ryoung
JR
Oh
Nam Sook
NS
Kim
Soo Hyung
SH
Lee
D000818:Animals; D004784:Environmental Monitoring; D005432:Flounder / Q000378:metabolism*; D007723:Korea; D014018:Tissue Distribution; D014220:Trialkyltin Compounds / Q000097:blood* / Q000493:pharmacokinetics
D014220:Trialkyltin Compounds; C011559:tributyltin