PENTA guidelines for the use of antiretroviral therapy in paediatric HIV infection. Pediatric European Network for Treatment of AIDS.
OBJECTIVE
To produce European Guidelines for the use of antiretroviral therapy (ART) in HIV-infected children.


METHODS
Systematic literature review using Medline, the major antiretroviral conference reports, and IDSA recommendations on guideline production.


METHODS
Pediatric European Network for Treatment of AIDS (PENTA) Steering Committee.


METHODS
Guidelines have been produced for the use of antiretroviral therapy in HIV-infected children in Europe. Recommendations on when to start ART and which ART to start, with dosages and a summary of the relevant literature, have been produced.


CONCLUSIONS
These guidelines are aimed at assisting paediatricians in Europe with ART prescribing, and provide a more cautious approach to starting therapy than current paediatric USA guidelines.
Paediatric Infectious Diseases Unit, St George's Hospital, London, UK. mike.sharland@stgeorges.nhs.uk
M
M
Sharland
G Castelli Gattinara
GC
di Zub
J Tomas
JT
Ramos
S
S
Blanche
D M
DM
Gibb
D019380:Anti-HIV Agents / Q000592:standards / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D017410:Practice Guidelines as Topic
D019380:Anti-HIV Agents