Role of residual spraying for malaria control in Belize.
We studied the impact of reduced residual spraying in Belize by developing a logistic regression model on relationships between numbers of houses sprayed (mostly with DDT) and numbers of malaria cases. We defined the "minimum effective house spray rate" (MEHSR) as the level of spraying that will prevent increases in malaria rates for a defined population. Under the total coverage approach (all houses sprayed), the MEHSR for Belize was 134.6. The model also showed that the odds for decreasing malaria is 1.086 for each increase of 10 houses sprayed per 1,000 population. In further testing, highly significant and differential changes in malaria rates were documented for paired groups of years with house spray rates that were either above or below the MEHSR. Numbers of malaria cases since 1995 are used to show how stratification methods are used in Belize to spray fewer houses (at levels below the MEHSR of 134.6).
Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799, USA.
Donald R
DR
Roberts
Erol
E
Vanzie
Michael J
MJ
Bangs
John P
JP
Grieco
Hilbert
H
Lenares
Paul
P
Hshieh
Eliska
E
Rejmankova
Sylvie
S
Manguin
Richard G
RG
Andre
Jorge
J
Polanco
D000818:Animals; D001531:Belize; D003634:DDT; D005544:Forecasting; D006798:Housing; D007306:Insecticides; D008288:Malaria / Q000517:prevention & control*; D009032:Mosquito Control / Q000379:methods*; D011157:Population Dynamics; D012044:Regression Analysis
D007306:Insecticides; D003634:DDT