Granulomatous angiitis of the central nervous system associated with herpes zoster.
Granulomatous angiitis of central nervous system (CNS) is a rare inflammatory disease of blood vessels mostly confined to CNS. We describe a case which presented with right sided hemiplegia with aphasia, after herpes zoster ophthalmicus. CT scan and MRI brain showed a large left sided infarct in the left middle cerebral artery (MCA) territory. MRI angiography revealed narrowing and thinning of left internal carotid artery (ICA) and to a lesser extent, left MCA suggestive of granulomatous vasculitis. Herpes zoster is often associated with major CNS involvement and a vascular etiology was previously postulated. Recent pathological reports suggest that cerebral angiitis secondary to herpes virus infection may be more common than realised.
Department of Medicine, SMS Medical College, Jaipur.
G
G
Bhat
D S
DS
Mathur
G N
GN
Saxena
S
S
Jain
A P
AP
Singh
D
D
Bhaduria
D000293:Adolescent; D002493:Central Nervous System Diseases / Q000150:complications / Q000175:diagnosis / Q000821:virology; D002536:Cerebral Arteries / Q000473:pathology*; D006429:Hemiplegia / Q000209:etiology* / Q000821:virology*; D006563:Herpes Zoster Ophthalmicus / Q000150:complications*; D006801:Humans; D008297:Male; D020293:Vasculitis, Central Nervous System / Q000473:pathology*