Early detection of central nervous system tuberculosis with the gen-probe nucleic Acid amplification assay: utility in an inner city hospital.
Central nervous system tuberculosis is a serious clinical problem, the treatment of which is sometimes hampered by delayed diagnosis. We investigated the utility of the Gen-Probe nucleic acid amplification assay for the rapid diagnosis of tuberculous meningitis and as a noninvasive method of identifying intracranial tuberculoma.
Department of Medicine, Hennepin County Medical Center, Minneapolis, MN, 55415, USA. bake0088@umn.edu.
Cristina A
CA
Baker
Charles P
CP
Cartwright
David N
DN
Williams
Susan M
SM
Nelson
Phillip K
PK
Peterson
D019937:Diagnostic Techniques and Procedures; D005784:Gene Amplification; D006786:Hospitals, Urban; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction / Q000379:methods*; D020306:Tuberculosis, Central Nervous System / Q000175:diagnosis* / Q000382:microbiology