Treatment of pseudobulbar laughter after gamma knife thalamotomy.
We describe a case of pathological laughter after gamma knife thalamotomy which resolved after treatment with sertraline. It is important to identify this potentially treatable complication of surgical therapy.
Okun
Michael S
MS
Emory University, Department of Neurology, Atlanta, Georgia, USA. msokun@dnamail.com
Heilman
Kenneth M
KM
Vitek
Jerrold L
JL
D006801:Humans; D007845:Laughter; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000601:surgery*; D020828:Pseudobulbar Palsy / Q000188:drug therapy / Q000209:etiology*; D016634:Radiosurgery / Q000009:adverse effects*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D020280:Sertraline / Q000627:therapeutic use; D013787:Thalamic Nuclei / Q000601:surgery*
D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline