One-pot synthetic route to homoallylketones via selective combination of alkyne, ethylene and aldehyde mediated by AlCl3 and zirconocene.
Zirconacyclopentenes generated in situ from alkynes and ethylene undergo selective reaction with aldehydes to afford homoallylketones in yields exceeding 70% in the presence of AlCl3.
Department of Chemistry, Peking University, Beijing 100871, China.
Changjia
C
Zhao
Tao
T
Yu
Zhenfeng
Z
Xi