Racial differences in prostate carcinogenesis. Histologic and clinical observations.
Racial differences in the prevalence of HGPIN and in the Gleason score of local stage cancers indicate that clinically observed racial differences in cancer incidence and stage at diagnosis reflect racial variability in prostate carcinogenesis. Exploration of genetic, hormonal, nutritional, and behavioral differences in black and white men may provide insight into the fundamental mechanisms of prostatic carcinogenesis and cancer progression.
Fowler
Jackson E
JE
Departments of Surgery and Urology, University of Mississippi School of Medicine, 2500 North State Street, Jackson, MS 39216, USA. jfowler@surgery.umsmed.edu
Bigler
Steven A
SA
D044383:Black People; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D015995:Prevalence; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000208:ethnology* / Q000235:genetics / Q000473:pathology; D044465:White People
D017430:Prostate-Specific Antigen