Syndrome of inappropriate secretion of antidiuretic hormone due to malignant thymoma.
The authors present the case of a 51-year-old female with a syndrome of inappropriate secretion of antidiuretic hormone (SIADH) due to a malignant thymoma. Laboratory examinations of the patient showed hyponatremia, plasma hypoosmolarity in the presence of concentrated urine and normal urine excretion of sodium. CT revealed a mass lesion in the mediastinum. A biopsy of the mediastinal mass was performed and the diagnosis of thymoma with SIADH was established. This is a rare description of a malignant thymoma associated with SIADH.
Galesic
K
K
Department of Medicine, Dubrava University Hospital, Zagreb, Croatia. kresog@zagreb.kbd.hr
Krizanac
S
S
Vrkljan
M
M
Ljubanovic
D
D
D000311:Adrenal Glands / Q000503:physiopathology; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology* / Q000503:physiopathology; D008875:Middle Aged; D013945:Thymoma / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D013953:Thymus Neoplasms / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D013961:Thyroid Gland / Q000503:physiopathology