Gem GTPase: between a ROCK and a hard place.
Gem GTPase is a member of a protein family that includes Rad, Rem and Rem2. Although until recently precious little was known about the function of Gem, recent studies have revealed that Gem may influence cell morphology by antagonising the actions of the Rho GTPase effector protein ROCK I.
Olson
Michael F
MF
Abramson Family Cancer Research Institute, BRB II/III, 421 Curie Blvd., University of Pennsylvania, Philadelphia 19104, USA. molson@mail.med.upenn.edu
D020558:GTP Phosphohydrolases / Q000378:metabolism*; D047908:Intracellular Signaling Peptides and Proteins; D010766:Phosphorylation; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D013379:Substrate Specificity; D054460:rho-Associated Kinases
D047908:Intracellular Signaling Peptides and Proteins; D017346:Protein Serine-Threonine Kinases; D054460:rho-Associated Kinases; D020558:GTP Phosphohydrolases