title: Assessing postoperative cognitive change after cardiopulmonary bypass surgery.
abstract: Cognitive decline after cardiopulmonary bypass (CPB) surgery has been a concern since the advent of CPB procedures. A primary focus of many studies on this topic has been to quantify the incidence of post-CPB cognitive impairment. However, studies that have used traditional parametric statistics have generally failed to confirm that long-lasting (> or = 1 month) cognitive declines occur reliably after CPB surgery. For the present study, the authors used a split-plot analysis of variance model that revealed preoperative memory impairments in the CPB patients and new postoperative impairments of attention. The authors discuss the assumptions of, and problems associated with, analysis methods that are often used to quantify the incidence of cognitive impairment following CPB surgery.
authors.affiliation: Department of Psychology, University of North Carolina at Wilmington, 28403-3297, USA. keithj@uncwil.edu
authors.forename: Julian R
authors.initials: JR
authors.lastname: Keith
authors.forename: Antonio E
authors.initials: AE
authors.lastname: Puente
authors.forename: Keri L
authors.initials: KL
authors.lastname: Malcolmson
authors.forename: Shane
authors.initials: S
authors.lastname: Tartt
authors.forename: Amy E
authors.initials: AE
authors.lastname: Coleman
authors.forename: Howard F
authors.initials: HF
authors.lastname: Marks
mesh_terms: D002315:Cardiopulmonary Bypass; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011183:Postoperative Complications; D011930:Reaction Time; D012720:Severity of Illness Index; D013028:Space Perception / Q000502:physiology; D011795:Surveys and Questionnaires; D014796:Visual Perception / Q000502:physiology