Alpha-methylenation/Diels-Alder tandem reaction promoted by ammonium salts generated in situ from secondary-tertiary diamines and alkoxymethyl chlorides.
A simple one-pot synthesis of spiranones from cycloketones and dienes promoted by an ammonium salt generated in situ from diamine and alkoxymethyl chloride through a tandem alpha-methylenation/Diels-Alder reaction is described.
Nakamura
Hiroko
H
Graduate School of Engineering, Nagoya University, SORST, Japan Science and Technology Corporation (JST), Chikusa, Nagoya 464-8603, Japan.
Yamamoto
Hisashi
H