Deduction of paternity index from DNA mixture.
Determination of individual genotypes in DNA mixture remains a challenge in forensic science. Using an approach of mixture of distributions, this article provides formula for calculation of paternity index (PI) in cases where only tissue mixture of the mother and alleged father, the genotypes of the mother and child, but not that of the alleged father are available. The formula has been used to solve a real case using mother's vaginal tissue contaminated with semen from alleged father.
Liao
Xiang Hai
XH
Department of Biochemistry, The Chinese University of Hong Kong, NT, Hong Kong SAR, PR China.
Lau
Tai Shang
TS
Ngan
Karenda Fai Ngor
KF
Wang
Jun
J
D016172:DNA Fingerprinting; D005260:Female; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008432:Mathematical Computing; D010334:Paternity; D010641:Phenotype; D011336:Probability