title: Synthesis of milbemycins beta9 and beta10 from milbemycins A3 and A4 and their biological activities.
abstract: Chemical derivation methods were used to prepare milbemycins beta9 and beta10 from milbemycins A3 and A4. Their acaricidal activities were also assessed against the organophosphorus-sensitive two-spotted spider mite (Tetranychus urticae) on primary leaves of cowpea plants (Vigna sinesis Savi species) by spraying.
authors.affiliation: Agroscience Research Laboratories, Sankyo Co. Ltd., Shiga, Japan. tukiya@yasu.sankyo.co.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsukiyama
authors.forename: Ayako
authors.initials: A
authors.lastname: Kinoshita
authors.forename: Reiji
authors.initials: R
authors.lastname: Ichinose
authors.forename: Kazuo
authors.initials: K
authors.lastname: Sato
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D007887:Fabaceae / Q000469:parasitology; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018515:Plant Leaves / Q000469:parasitology; D040102:Tetranychidae / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; C471414:milbemycin beta10; C471413:milbemycin beta9; C027837:moxidectin