title: Modern trends in the speciation of selenium by hyphenated techniques.
abstract: The complexity of selenium speciation in the environment and in living organisms results in broad analytical challenges. The importance of the selective determination of the particular species of this element, to understand its metabolism and biological significance in clinical chemistry, biology, toxicology, and nutrition, calls for state-of-the-art analytical techniques. In this paper hyphenated techniques are evaluated with particular emphasis on interfaced separation with element-selective detection and identification of the selenium compounds detected.
authors.affiliation: Department of Chemistry, University of Massachusetts, 701 Lederle Graduate Research Center, 710 North Pleasant St., Amherst, MA 01003-9336, USA. pcuden@chem.umass.edu
authors.forename: Peter C
authors.initials: PC
authors.lastname: Uden
mesh_terms: D002849:Chromatography, Gas / Q000379:methods; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D011506:Proteins / Q000032:analysis / Q000737:chemistry; D012643:Selenium / Q000032:analysis*; D017279:Selenocysteine / Q000737:chemistry / Q000302:isolation & purification; D051140:Selenoproteins
chemical_list: D011506:Proteins; D051140:Selenoproteins; D017279:Selenocysteine; D012643:Selenium