title: [Symmetrical peripheral gangrene of unknown etiology].
abstract: We describe the case of a 19-year-old female patient who presented with acute symmetrical peripheral gangrene (SPG), including all fingers and toes. Further diagnostic work-up did not reveal any underlying condition other than a non-specific transient cryoglobulinemia. Despite immediate anticoagulopathic and anti-inflammatory treatment, all fingers and toes had to be amputated.
authors.affiliation: Division of Plastic, Reconstructive, Maxillofacial and Oral Surgery, Department of Surgery, Duke University Medical Center, Box 3181, Durham, NC 27710, USA.
authors.forename: Theda E
authors.initials: TE
authors.lastname: Schuh
authors.forename: D
authors.initials: D
authors.lastname: Erdmann
authors.forename: L S
authors.initials: LS
authors.lastname: Levin
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D015901:Angiography, Digital Subtraction; D001780:Blood Coagulation Tests; D003449:Cryoglobulinemia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005385:Fingers / Q000098:blood supply / Q000473:pathology / Q000601:surgery*; D005734:Gangrene / Q000601:surgery*; D006801:Humans; D009336:Necrosis; D014034:Toes / Q000098:blood supply / Q000473:pathology / Q000601:surgery*