title: Could an echo contrast agent be helpful in identifying renal artery stenosis?
abstract: BACKGROUND
  Diagnosis of renal artery stenosis using echo color-Doppler is subjected to several limitations. The aim of this study was to examine if the routine use of a contrast agent could be helpful in identifying renal artery stenosis (RAS).
  
  
  METHODS
  We analysed 35 patients affected by RAS using an echo color-Doppler coupled with a contrast agent. All patients presented arterial hypertension, with a good drugs control, and mean serum creatinine of 1.8 mg/dL. All patients previously underwent angiography. RAS was at the origin of the artery in 27 patients, at the intermediate tract in 8. All patients had already been submitted to a basal echo color-Doppler.
  
  
  RESULTS
  The contrast agent determined a significant increase in the average colour signal in all the subjects, and a better evaluation of the spectral waveforms, if compared to the basal examination.
  
  
  CONCLUSIONS
  The results obtained showed that the contrast agent doesn't improve the diagnosis of RAS, especially in vascular origin stenosis, while it shows a real advantage in the intermediate or distal stenosis which are better visualized.
authors.affiliation: Department of Clinic Medicine, Service of Ultrasonography Vascular Diagnosis, Chair of Nephrology, Sant'Andrea Hospital, Rome, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Cianci
authors.forename: S
authors.initials: S
authors.lastname: Lai
authors.forename: A
authors.initials: A
authors.lastname: Mander
authors.forename: G
authors.initials: G
authors.lastname: Coen
authors.forename: P
authors.initials: P
authors.lastname: Mitterhofer
authors.forename: M
authors.initials: M
authors.lastname: Vitale
authors.forename: G
authors.initials: G
authors.lastname: Ciano
authors.forename: G
authors.initials: G
authors.lastname: Stirati
authors.forename: P
authors.initials: P
authors.lastname: Manfredini
authors.forename: G
authors.initials: G
authors.lastname: Clemenzia
mesh_terms: D000293:Adolescent; D000328:Adult; D003287:Contrast Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color / Q000379:methods*
chemical_list: D003287:Contrast Media