title: Evidence that taste buds are not present on the human adult uvula.
abstract: We conducted a study to investigate whether taste buds are present on the human adult uvula. Our impetus was to determine whether surgical procedures that involve removal of the uvula can affect taste perception. Five human uvulae were removed via a modified carbon dioxide laser-assisted uvulopalatoplasty in an outpatient office setting. The uvulae were serially sectioned and stained with a solution specific for membrane-bound calcium-modulated adenosine triphosphatase, a high concentration of which is found in taste receptors. Examination of the stained sections under light microscopy failed to show that any taste receptors were present in any of the uvulae. This finding suggests that the taste disturbances noted after surgical procedures involving removal of the uvula are not attributable to a loss of taste receptors.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, 925 Chestnut St., Sixth Floor, Philadelphia, PA 19107, USA.
authors.forename: Bryan T
authors.initials: BT
authors.lastname: Ambro
authors.forename: Edmund A
authors.initials: EA
authors.lastname: Pribitkin
authors.forename: Linda
authors.initials: L
authors.lastname: Wysocki
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Brand
authors.forename: William M
authors.initials: WM
authors.lastname: Keane
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D013650:Taste Buds / Q000033:anatomy & histology*; D014609:Uvula / Q000033:anatomy & histology*