title: A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis.
abstract: Two new natural products, the phenanthrenoid puguenolide (6-hydroxy-3-methoxy-4-oxapyren-5-one) and isoangoletin were isolated from the stem bark of the newly described Uvaria species, U. puguensis D.M. Johnson, together with the sesquiterpene guaiol and the usual C-benzyldihydrochalcones previously found in the genus Uvaria, viz. uvaretin, diuvaretin, chamuvaritin and a mixture of triuvaretin and isotriuvaretin. Structural elucidation was achieved through a combination of spectroscopic methods.
authors.affiliation: Department of Chemistry, University of Dar es Salaam, Tanzania.
authors.forename: John J
authors.initials: JJ
authors.lastname: Makangara
authors.forename: Stephan A
authors.initials: SA
authors.lastname: Jonker
authors.forename: Mayunga H H
authors.initials: MH
authors.lastname: Nkunya
mesh_terms: D002599:Chalcone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification*; D016488:Medicine, African Traditional; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification*; D024301:Plant Bark / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification*; D017550:Spectroscopy, Fourier Transform Infrared; D013636:Tanzania; D031046:Uvaria / Q000737:chemistry*
chemical_list: C469882:6-hydroxy-3-methoxy-4-oxapyren-5-one; D006576:Heterocyclic Compounds, 4 or More Rings; D010616:Phenanthrenes; D011753:Pyrones; C469881:isoangoletin; D002599:Chalcone