title: Selenium status of Irish adults: evidence of insufficiency.
abstract: BACKGROUND
  Sub-optimal selenium status may have a role in the aetiology of various pathologies. Selenium status depends on adequate selenium in the diet. A relatively high proportion of Irish adults (17% men; 46% women) have an inadequate dietary intake.
  
  
  OBJECTIVE
  A study was designed to examine the selenium status of healthy Irish adults.
  
  
  METHODS
  Ninety-one healthy Irish adults, aged 18-67 years, were recruited from the Cork City area. A fasting blood sample was collected from each subject and each was assayed for serum selenium an index of serum selenium.
  
  
  RESULTS
  Mean (+/- SD) serum selenium concentration in healthy Irish adults was 76 (+/- 21)microg/l. There was no significant difference in values between males and females or between postmenopausal and premenopausal women or between the three main age categories.
  
  
  CONCLUSIONS
  Current serum selenium values of Irish adults would not appear to be sufficient to achieve optimal activity of glutathione peroxidase, which occurs at serum selenium concentration around 95microg/l. Sub-optimal selenium status may increase susceptibility to various chronic disorders.
authors.affiliation: Department of Food Science, Food Technology and Nutrition, University College, Cork, Ireland.
authors.forename: J
authors.initials: J
authors.lastname: Murphy
authors.forename: K D
authors.initials: KD
authors.lastname: Cashman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007494:Ireland; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D012643:Selenium
chemical_list: D012643:Selenium