title: Globulixanthones C, D and E: three prenylated xanthones with antimicrobial properties from the root bark of Symphonia globulifera.
abstract: Two prenylated xanthone derivatives, named globulixanthones C and D and one bis-xanthone, designated globulixanthone E, have been isolated from the root bark of Symphonia globulifera. The structures of these compounds were elucidated by a detailed spectroscopic analysis. They have been shown to exhibit in vitro significant antimicrobial activity against a range of micro-organisms.
authors.affiliation: Department of Organic Chemistry, Faculty of Science University of Yaounde I, PO Box 812, Yaounde, Cameroon. ankengf@uycdc.uninet.cm
authors.forename: Augustin E
authors.initials: AE
authors.lastname: Nkengfack
authors.forename: Pierre
authors.initials: P
authors.lastname: Mkounga
authors.forename: Michele
authors.initials: M
authors.lastname: Meyer
authors.forename: Zacharias T
authors.initials: ZT
authors.lastname: Fomum
authors.forename: Bernard
authors.initials: B
authors.lastname: Bodo
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D014197:Trees / Q000737:chemistry*; D014966:Xanthenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D014966:Xanthenes