Adjuvant chemotherapy for high-risk low-stage germ-cell tumours.
OBJECTIVE
To review the assessment and management of early germ-cell tumours.


RESULTS
A role has evolved for adjuvant chemotherapy in stage I disease postorchidectomy and in the primary management of stage II disease.


CONCLUSIONS
A range of approaches offer high survival in early germ-cell tumours. Treatment should factor in patient choice and resource issues. More sensitive imaging with Positron Emission Tomography may allow more appropriate treatment decisions.
Horwich
Alan
A
The Academic Unit of Radiotherapy and Oncology, The Royal Marsden NHS Trust and The Institute of Cancer Research, Sutton, Surrey UK.
Huddart
Robert A
RA
D017024:Chemotherapy, Adjuvant; D018237:Germinoma / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009919:Orchiectomy; D018570:Risk Assessment; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery