title: Phytochemical based strategies for nematode control.
abstract: This review examines the discovery of naturally occurring phytochemicals antagonistic toward plant-parasitic and other nematodes. Higher plants have yielded a broad spectrum of active compounds, including polythienyls, isothiocyanates, glucosinolates, cyanogenic glycosides, polyacetylenes, alkaloids, lipids, terpenoids, sesquiterpenoids, diterpenoids, quassinoids, steroids, triterpenoids, simple and complex phenolics, and several other classes. Many other antinematodal compounds have been isolated from biocontrol and other fungi. Natural products active against mammalian parasites can serve as useful sources of compounds for examination of activity against plant parasites. The agricultural utilization of phytochemicals, although currently uneconomic in many situations, offers tremendous potential.
authors.affiliation: Nematology Laboratory, USDA-ARS, Building 011A, BARC-West, Beltsville, Maryland 20705, USA. chitwood@ba.ars.usda.gov
authors.forename: David J
authors.initials: DJ
authors.lastname: Chitwood
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000969:Antinematodal Agents / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry; D019607:Brassicaceae / Q000737:chemistry; D056890:Eukaryota / Q000737:chemistry / Q000302:isolation & purification; D005227:Fatty Acids / Q000737:chemistry / Q000494:pharmacology; D005658:Fungi / Q000737:chemistry / Q000302:isolation & purification; D005961:Glucosinolates / Q000737:chemistry / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000494:pharmacology; D006790:Host-Parasite Interactions / Q000187:drug effects; D009348:Nematoda / Q000187:drug effects* / Q000382:microbiology; D010572:Pest Control, Biological / Q000379:methods*; D010636:Phenols / Q000737:chemistry / Q000494:pharmacology; D010935:Plant Diseases / Q000469:parasitology*; D013729:Terpenes / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D000969:Antinematodal Agents; D005227:Fatty Acids; D005961:Glucosinolates; D006027:Glycosides; D010636:Phenols; D013729:Terpenes; C007173:cyanogenic glycosides