Two cases of pediatric neuroblastoma with tumor thrombus in the inferior vena cava.
The authors describe two children with abdominal neuroblastoma with radiographic evidence of tumor extension into the inferior vena cava. Imaging studies were suggestive of Wilms tumor, but histologic analysis revealed neuroblastoma. In one patient a pulmonary embolus developed after initiation of cytotoxic therapy; the second patient was prophylactically anticoagulated and had no embolic event.
Bagatell
Rochelle
R
Department of Pediatrics and Steele Memorial Children's Research Center, Tucson, Arizona, USA. bagatell@peds.arizona.edu
Morgan
Elaine
E
Cosentino
Catherine
C
Whitesell
Luke
L
D000925:Anticoagulants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D009360:Neoplastic Cells, Circulating / Q000187:drug effects / Q000473:pathology*; D009447:Neuroblastoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D011655:Pulmonary Embolism / Q000209:etiology; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging / Q000473:pathology*; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*
D000925:Anticoagulants; D000970:Antineoplastic Agents; D006493:Heparin