Primary antiphospholipid syndrome presenting with a branch retinal artery occlusion in a 15-year-old boy.
Acute vascular events are rare in the pediatric population, but there is an association with the presence of antiphospholipid antibodies. When there is no other underlying medical disorder, this is referred to as primary antiphospholipid syndrome. We present a case of a 15-year-old boy who developed an acute superior branch retinal artery occlusion. Complete evaluation revealed significant elevations in antiphospholipid antibodies. To our knowledge, there are no cases in children of primary antiphospholipid syndrome presenting with this clinical manifestation.
Saxonhouse
Matthew A
MA
Department of Pediatrics, Shands Children's Hospital, University of Florida, Gainesville 32610-0296, USA. saxonma@peds.ufl.edu
Bhatti
M Tariq
MT
Driebe
William T
WT
Freeman
Bridget E
BE
Maria
Bernard L
BL
Carney
Paul R
PR
D000293:Adolescent; D017153:Antibodies, Anticardiolipin / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D003937:Diagnosis, Differential; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D016682:Lupus Coagulation Inhibitor / Q000276:immunology; D008297:Male; D010211:Papilledema / Q000150:complications / Q000175:diagnosis; D015356:Retinal Artery Occlusion / Q000150:complications / Q000175:diagnosis*
D017153:Antibodies, Anticardiolipin; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D016682:Lupus Coagulation Inhibitor