title: Adjuvant pelvic irradiation in patients with node-negative carcinoma of the uterine cervix.
abstract: BACKGROUND
  To assess the role of post-operative pelvic radiotherapy in cervical cancer patients without lymph node metastases.
  
  
  METHODS
  The records of 61 patients with cervical cancer treated with radical hysterectomy and bilateral pelvic lymphadenectomy followed by pelvic irradiation were reviewed. The distribution of FIGO stage was IB in 34, II4 in 5 and IIB in 22. The patients were treated with 10-18 MV X-rays using a fractional daily dose of 1.8-2.0 Gy to a median total dose of 50 Gy.
  
  
  RESULTS
  The actuarial 5-year pelvic control rate was 95%. There was no isolated pelvic lymph node recurrence. The overall 5-year survival of the entire group was 89%. The mean age of the patients who developed recurrence was lower than the other patients (46 years vs. 53 years, p=0.07).
  
  
  CONCLUSIONS
  The results indicated that post-operative pelvic irradiation was effective in preventing pelvic recurrence in patients with node-negative cervical cancer.
authors.affiliation: Department of Radiation Oncology, Chiba University, School of Medicine, Chiba City, Japan. unotakas@ho.chiba-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Uno
authors.forename: Hisao
authors.initials: H
authors.lastname: Ito
authors.forename: Shigeo
authors.initials: S
authors.lastname: Yasuda
authors.forename: Takashi
authors.initials: T
authors.lastname: Aruga
authors.forename: Koichi
authors.initials: K
authors.lastname: Isobe
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kawakami
authors.forename: Akira
authors.initials: A
authors.lastname: Mitsuhashi
authors.forename: Naotake
authors.initials: N
authors.lastname: Tanaka
authors.forename: Kouji
authors.initials: K
authors.lastname: Yamazawa
authors.forename: Kiyomi
authors.initials: K
authors.lastname: Suzuka
authors.forename: Souei
authors.initials: S
authors.lastname: Sekiya
authors.forename: Jun
authors.initials: J
authors.lastname: Itami
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Shigematsu
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kubo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery