title: Life-style vaccines.
abstract: Multiple immunotherapy approaches are under development to treat various chronic diseases or conditions. Thanks to dramatic technological improvements, the field of vaccinology can now extend from prophylaxis to therapy, and from infectious diseases to dysimmune disorders like cancer or autoimmunity, or even to non-immune related conditions, including neurological or cardiovascular disorders. Life-style vaccines defined as vaccines to manage chronic conditions in healthy individuals can, therefore, also be envisaged. Three examples will be reviewed and discussed here, from both technical and ethical aspects: contraceptive vaccines, vaccines to treat addictions, and anti-dental caries vaccines.
authors.affiliation: GlaxoSmithKline Biologicals, Rixensart, Belgium.
authors.forename: Pascal
authors.initials: P
authors.lastname: Mettens
authors.forename: Philippe
authors.initials: P
authors.lastname: Monteyne
mesh_terms: D003731:Dental Caries / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D013290:Streptococcal Infections / Q000517:prevention & control; D019966:Substance-Related Disorders / Q000628:therapy*; D014611:Vaccination / Q000379:methods*; D022642:Vaccines, Contraceptive
chemical_list: D022642:Vaccines, Contraceptive