[Severe aortic valve stenosis and coronary disease in the elderly. Epidemiology and hemodynamic features].
BACKGROUND
Aortic valve replacement is an effective and safe intervention in the elderly, but to-day the prevalence of coronary artery disease in the elderly has still to be clarified. Aim of this paper is to analyze in a retrospective study the epidemiology and the hemodynamic relation of the association of severe aortic valve stenosis with coronary artery disease in patients over 75 years.


METHODS
In a retrospective study of 12.000 cardiac catheterization procedures, patients with severe aortic valve stenosis were selected: the patients over 75 years (30 patients) were screened for presence/absence of coronary lesion forming two groups: correlations with anatomic and hemodynamic variables were made.


RESULTS
36.6% (11 patients) of the over-75 had significative coronary lesions; the coronary arteries involved were the anterior descendent coronary artery and the right coronary artery; no significative differences were found as to risk factors between the two groups except hypertension; the greater number of calcifications and mitral and aortic regurgitation was found in patients with coronary disease; the values of ejection fraction and cardiac index were significantly smaller in patients with coronary disease.


CONCLUSIONS
In patients over 75 the severe aortic valve stenosis is frequently associated with coronary disease and the association is greater than in younger persons; some particular features confirm the elderly patients as a class at particular risk in which coronary angiography and combined bypass graft and valve replacement are of primary importance for the outcomes.
Rigatelli
G
G
Laboratorio di Emodinamica e Cardiologia Interventistica, Divisione di Cardiologia, Ospedale Civile di Legnago, Legnago Verona, Italy.
Franco
G F
GF
Gemelli
M
M
Bolomini
L
L
Rossi
P
P
Rigatelli
G
G
D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology*; D003327:Coronary Disease / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012720:Severity of Illness Index