Lysosomal-cationic test and NBT reduction test just partially reflect the completeness of phagocytic process in human granulocytes.
The results of NBT test correlated with the index of phagocytosis completeness in only 43% of 21 clinically healthy volunteers. The level of the lysosomal-cationic test was significantly reduced only if the phagocytosis completeness index was markedly decreased. The latter is an integral value reflecting the bactericidal activity of granulocytes.
Belokrylov
G A
GA
Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg.
Popova
O Ya
OY
D000328:Adult; D001431:Bacteriological Techniques / Q000379:methods; D002412:Cations; D005260:Female; D006098:Granulocytes / Q000382:microbiology*; D006801:Humans; D007202:Indicators and Reagents; D008247:Lysosomes; D008297:Male; D008875:Middle Aged; D010587:Phagocytosis; D013210:Staphylococcus / Q000276:immunology*; D013778:Tetrazolium Salts
C094100:2,2'-di-4-nitrophenyl-5,5'-diphenyl-3,3'-(3,3'-dimethoxy-4,4'-diphenylene)ditetrazolium; D002412:Cations; D007202:Indicators and Reagents; D013778:Tetrazolium Salts