Precise firing events are conserved across neurons.
Sensory neurons can respond to dynamic stimuli with temporally precise firing events. In the lateral geniculate nucleus (LGN) of the thalamus, we found previously that when a flickering visual stimulus was repeated, individual cells fired action potentials at the same time in every trial to within 1 msec. We now show that these precise firing events are also reproducible across cells of the same class. Therefore, the mechanisms for producing precise timing must be conserved within a cell class. Our results further suggest that cortical neurons would require only a few generic processing mechanisms to extract the fine temporal information available in their LGN inputs.
Reinagel
Pamela
P
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Reid
R Clay
RC
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002415:Cats; D004567:Electrodes, Implanted; D005829:Geniculate Bodies / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000145:classification / Q000502:physiology*; D016011:Normal Distribution; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors; D014795:Visual Pathways / Q000166:cytology / Q000502:physiology