title: Preparation of monodisperse controlled release microcapsules.
abstract: Since the handling of many active agents in its pure form has many problems, microencapsulation is used to have better properties in the product. With the patented BRACE-Processes it is possible to encapsulate a very wide range of materials in monodisperse Microspheres or Microcapsules in a diameter range of 50-6000 microm with a very narrow size distribution. The Microsphere Units from BRACE can be customer tailored to the materials and all necessary specifications as FDA, GMP/GLP, EX, CIP, WIP etc. The throughput of the BRACE Microsphere Units ranges between 10 ml per h (small laboratory scale) up to over 1000 l per h (production scale) while the production cost are very low, especially if compared directly to competitive processes as spray-drying or fluidized bed coating.
authors.affiliation: BRACE GmbH, Taunusring 50, Alzenau, Germany. info@brace.de
authors.forename: Thorsten
authors.initials: T
authors.lastname: Brandau
mesh_terms: D002214:Capsules; D004339:Drug Compounding / Q000295:instrumentation / Q000379:methods*; D005079:Excipients; D008863:Microspheres; D010316:Particle Size; D013501:Surface-Active Agents
chemical_list: D002214:Capsules; D005079:Excipients; D013501:Surface-Active Agents