title: The progenitor cells of the embryonic telencephalon and the neonatal anterior subventricular zone differentially regulate their cell cycle.
abstract: For the last 10 years our laboratory has been studying the proliferation, migration and differentiation of neuronal progenitor cells located in the anterior part of the postnatal forebrain subventricular zone (SVZa). SVZa-derived cells possess a number of proliferative characteristics that distinguish them from the other progenitor cells in the central nervous system. This review summarizes our recent findings, in which we compared the pattern of cell cycle inhibitory proteins expressed by the neonatal SVZa to that of telencephalic ventricular zone cells.
authors.affiliation: Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. luskin@cellbio.emory.edu
authors.forename: Marla B
authors.initials: MB
authors.lastname: Luskin
authors.forename: Volkan
authors.initials: V
authors.lastname: Coskun
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002453:Cell Cycle / Q000502:physiology; D018797:Cell Cycle Proteins; D002454:Cell Differentiation / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D002552:Cerebral Ventricles / Q000166:cytology* / Q000196:embryology / Q000378:metabolism; D019941:Cyclin-Dependent Kinase Inhibitor p16 / Q000096:biosynthesis; D050764:Cyclin-Dependent Kinase Inhibitor p19; D006801:Humans; D009474:Neurons / Q000166:cytology / Q000378:metabolism; D016548:Prosencephalon / Q000166:cytology; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism; D013687:Telencephalon / Q000166:cytology* / Q000196:embryology / Q000378:metabolism
chemical_list: C493974:CDKN2D protein, human; D018797:Cell Cycle Proteins; D019941:Cyclin-Dependent Kinase Inhibitor p16; D050764:Cyclin-Dependent Kinase Inhibitor p19