title: Chronic fatigue after radiotherapy for carcinoma of the prostate: correlation with anorectal and genitourinary function.
abstract: In an investigation of chronic fatigue in patients treated with radical or post-operative radiotherapy for carcinoma of the prostate, the Brief Fatigue Inventory, urinary and anorectal function questionnaires were completed by 103 patients 2.1 years (median) after treatment. The mean fatigue score (2.8+/-2.3) and the rate of severe fatigue (18.7%) were higher than published data for healthy controls (2.2+/-1.8 and 5%, respectively). Fatigue was significantly correlated with fecal incontinence and urinary symptoms, suggesting an association of chronic fatigue and late radiation toxicity in carcinoma of the prostate.
authors.affiliation: Department of Radiation Oncology, University of Würzburg, Josef-Schneider-Strasse 11, Germany.
authors.forename: Dirk
authors.initials: D
authors.lastname: Vordermark
authors.forename: Michael
authors.initials: M
authors.lastname: Schwab
authors.forename: Michael
authors.initials: M
authors.lastname: Flentje
authors.forename: Marco
authors.initials: M
authors.lastname: Sailer
authors.forename: Oliver
authors.initials: O
authors.lastname: Kölbl
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005221:Fatigue / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005242:Fecal Incontinence / Q000209:etiology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011788:Quality of Life; D011878:Radiotherapy / Q000009:adverse effects*; D012007:Rectum; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014570:Urologic Diseases / Q000209:etiology