title: Effects of trauma and pain on the acute anterior pituitary hormonal response.
abstract: The aim of this study was to compare the effects of trauma and pain on the pituitary gland so as to determine whether pain is a significant component in the general acute hormonal trauma response. Adenohypophysis of rabbits that have undergone either diffuse traumatic brain injury or pain were investigated using immunohistochemistry. The ACTH staining pattern of the pain-administered rabbits was not as strong as the head-trauma-administered group, whereas PRL staining pattern of the former group was not so weak as the later group. As a conclusion, since adrenocorticotrophic hormone and prolactin staining patterns were different in the trauma administered and pain induced groups; it may be postulated that pain alone may not be an important factor in the hormonal response to trauma.
authors.affiliation: Department of Anatomy, Gazi University Medical School, Beşevler, Ankara, Turkey.
authors.forename: R
authors.initials: R
authors.lastname: Gözil
authors.forename: T
authors.initials: T
authors.lastname: Evrenkaya
authors.forename: Z
authors.initials: Z
authors.lastname: Keskil
authors.forename: E
authors.initials: E
authors.lastname: Calgüner
authors.forename: S
authors.initials: S
authors.lastname: Keskil
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D018409:Foot Injuries / Q000503:physiopathology*; D013006:Growth Hormone / Q000378:metabolism; D016489:Head Injuries, Closed / Q000503:physiopathology*; D008297:Male; D010146:Pain / Q000503:physiopathology*; D010903:Pituitary Gland, Anterior / Q000737:chemistry / Q000378:metabolism* / Q000473:pathology; D011388:Prolactin / Q000378:metabolism*; D011817:Rabbits; D013972:Thyrotropin / Q000378:metabolism
chemical_list: D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013972:Thyrotropin; D013006:Growth Hormone