Two new molecular PML-RARalpha variants: implications for the molecular diagnosis of APL.
Vizmanos
José Luis
JL
Department of Genetics, School of Science, University of Navarre, C/Irunlarrea s/n E-31080 Pamplona, Navarre, Spain. jlvizmanos@unav.es
Larrráyoz
María José
MJ
Odero
María Dolores
MD
Lasa
Ramón
R
González
Marcos
M
Novo
Francisco Javier
FJ
Calasanz
María José
MJ
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D019457:Chromosome Breakage; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics* / Q000648:ultrastructure; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics* / Q000648:ultrastructure; D003199:Computer Systems; D004252:DNA Mutational Analysis; D017931:DNA Primers; D005091:Exons / Q000235:genetics; D005188:False Negative Reactions; D006801:Humans; D007438:Introns / Q000235:genetics; D007621:Karyotyping; D015473:Leukemia, Promyelocytic, Acute / Q000175:diagnosis* / Q000235:genetics; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000235:genetics*; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D020033:Protein Isoforms / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D012334:RNA, Neoplasm / Q000235:genetics; D012074:Remission Induction; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014178:Translocation, Genetic / Q000235:genetics*
D017931:DNA Primers; D009363:Neoplasm Proteins; D015514:Oncogene Proteins, Fusion; D020033:Protein Isoforms; D012333:RNA, Messenger; D012334:RNA, Neoplasm; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein