title: Hemolytic uremic syndrome after chemotherapy with gemcitabine and taxotere: a case report.
abstract: A case of hemolytic uremic syndrome is reported in a female patient affected by metastatic breast carcinoma receiving chemotherapy with gemcitabine and docetaxel. Up to now this is the first case that has been reported in the medical literature in patients treated with docetaxel (taxotere)and gemcitabine. The patient developed hemolytic uremic syndrome after the third cycle of chemotherapy. She was treated with diuretics, steroids, antibiotics, antifungal drugs, erythropoietin and fluid replacement. The patient underwest dialysis, and survived the hemolytic uremic syndrome. It was not possible to ascertain if the hemolytic uremic syndrome was related to the chemotheraputic treatment or the cancer itself.
authors.affiliation: Division of Oncohematology, University of Palermo, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Citarrella
authors.forename: Vittorio
authors.initials: V
authors.lastname: Gebbia
authors.forename: Michele
authors.initials: M
authors.lastname: Teresi
authors.forename: Salvatore
authors.initials: S
authors.lastname: Miceli
authors.forename: Giovanna
authors.initials: G
authors.lastname: Sciortino
authors.forename: Marina
authors.initials: M
authors.lastname: Vaglica
authors.forename: Nicolina
authors.initials: N
authors.lastname: Pizzardi
authors.forename: Sergio
authors.initials: S
authors.lastname: Palmeri
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy; D003841:Deoxycytidine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D000077143:Docetaxel; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000139:chemically induced* / Q000209:etiology / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D043823:Taxoids; D000093542:Gemcitabine
chemical_list: D043823:Taxoids; D003841:Deoxycytidine; D000077143:Docetaxel; D017239:Paclitaxel; D000093542:Gemcitabine