New-types of apparatus for producing microcapsules and microgranules.
Two types of simple compact apparatuses for microencapsulation and microgranulation have been developed. The vibration-type apparatus is a better fit for producing gel-like microgranules of 1.5-3.0 mm in diameter to be used in production of food (fodder) products and additives and microgranulated cell culture. The spray apparatus is fit for operation in two modes: drop-forming (particles of 100-500 microm in diameter) and spray modes (particles of 10-50 microm in diameter). The apparatus is most efficient when used in the mode of forming the particles directly in the medium of liquid nitrogen with successive lyophilic drying (without preliminary defrosting). It is used for microgranulating the live virus materials with their virulence being preserved.
Vilesov
Alexander D
AD
AOZT Delivery Systems International, Dobrolybov av.14, 197198, St. Petersburg, Russia. delsi@mail.wplus.net
Zhuravsky
Eugene P
EP
Vilessova
Marina S
MS
Netchaeva
Elena A
EA
Ayzenshtadt
Natalya I
NI
Stankevich
Richard P
RP
Isidorov
Roman V
RV
D000180:Acrylic Resins / Q000737:chemistry; D004339:Drug Compounding / Q000295:instrumentation*; D005079:Excipients; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D018697:Nootropic Agents / Q000008:administration & dosage / Q000737:chemistry; D010316:Particle Size; D010889:Piracetam / Q000008:administration & dosage / Q000737:chemistry; D011208:Powders; D014732:Vibration
D000180:Acrylic Resins; D005079:Excipients; D018697:Nootropic Agents; D011208:Powders; C006903:carbopol 940; D010889:Piracetam