title: Intravenous verapamil blunts hyperdynamic responses during electroconvulsive therapy without altering seizure activity.
abstract: A dose of 0.1 mg/kg of verapamil, administered immediately before anesthesia, significantly reduces the increase in peak heart rate and mean arterial blood pressure after electroconvulsive therapy. Furthermore, the administration of verapamil does not reduce the duration of the seizure.
authors.affiliation: Department of Anesthesia, Chiba Hokusoh Hospital, Nippon Medical School, Chiba, Japan. HFB01245@nifty.com
authors.forename: Zen'ichiro
authors.initials: Z
authors.lastname: Wajima
authors.forename: Tatsusuke
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Akira
authors.initials: A
authors.lastname: Ogura
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Imanaga
authors.forename: Toshiya
authors.initials: T
authors.lastname: Shiga
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Inoue
authors.forename: Ryo
authors.initials: R
authors.lastname: Ogawa
mesh_terms: D000328:Adult; D000368:Aged; D000758:Anesthesia; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000494:pharmacology*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D004562:Electrocardiography / Q000187:drug effects; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D012640:Seizures / Q000503:physiopathology; D014700:Verapamil / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D002121:Calcium Channel Blockers; D014700:Verapamil