[Supplemental multivitamin and multimineral preparations during normal pregnancy--effect on a fetus and delivery].
The aim of this prospective study is to assess the effect of non indicated supplementation with Materna during normal pregnancy on some parameters of the neonate and the process of delivery. The material includes 98 women who had been taking Materna during the pregnancy and 27 cases without any medications. The criteria for inclusion are: normally progressing clinically and paraclinically pregnancy and delivery after completing 37th w.g. (95% confident interval 39.0-40.5).


RESULTS
Most of the pregnant women take Materna for 3 to 5 months (95% CI) during pregnancy. The supplementation with Materna lead to increase of the BIP from the control group of 94.4 mm to 96.5; the occipitofrontal circumference from 33.9 to 35.1 and the high of the neonate from 50.2 to 51.1 respectively. The impression of the obstetricians engage in the study is that the scull bones are more solid and the molding of the head after the delivery is very small or even missing.


CONCLUSIONS
Unjustified supplementation of normal pregnancy with multivitamins and multiminerals lead to increase in the occipitofrontal circumference and to the decrease of the molding capacity of the fetal head wherefore the labor prolongs and the rate of CS and the operative vaginal deliveries increase.
Dimitrov
A
A
Krŭsteva
K
K
Nikolov
A
A
Tsankova
M
M
Nashar
S
S
D001827:Body Height / Q000187:drug effects; D002508:Cephalometry; D002585:Cesarean Section; D019587:Dietary Supplements / Q000009:adverse effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D008903:Minerals; D007744:Obstetric Labor Complications / Q000139:chemically induced; D011247:Pregnancy / Q000378:metabolism; D011295:Prenatal Care; D011446:Prospective Studies; D014815:Vitamins / Q000009:adverse effects / Q000627:therapeutic use*
D008903:Minerals; D014815:Vitamins