Atopic dermatitis: therapeutic challenge in an infant with dystrophic epidermolysis bullosa.
Inherited epidermolysis bullosa (EB) manifests as blisters that usually result from minor trauma. The severity of expression ranges from mild occasional blistering to severe extensive bullae. We report an infant with dystrophic EB worsened by atopic dermatitis (AD). This concomitant skin disease exacerbated EB, because scratching induced bullae and milia. Careful management of AD provided a marked improvement in cutaneous involvement. This report shows that it is important to document and treat inflammatory skin disorders coexisting with EB, because they may influence the overall prognosis of EB.
Sibaud
V
V
Paediatric Dermatology Unit, Hôpital Pellegrin, Place Amelie Raba-Léon, 33076 Bordeaux cedex 9, France.
Roul
S
S
Leaute-Labreze
C
C
Memeguzi
G
G
Taïeb
A
A
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000150:complications* / Q000276:immunology / Q000628:therapy*; D004643:Emollients / Q000627:therapeutic use; D016108:Epidermolysis Bullosa Dystrophica / Q000150:complications* / Q000276:immunology; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D007231:Infant, Newborn; D010328:Patch Tests
D000893:Anti-Inflammatory Agents; D004643:Emollients; D005938:Glucocorticoids