title: Profile of solvent abusers (glue sniffers) in East Malaysia.
abstract: Solvent abuse is deliberate sniffing of an organic solvent for the intention of altering the physiological state of the individual. It is also commonly known as glue sniffing because glue is the most commonly abused substance. This form of substance abuse is widespread throughout the world and usually popular among secondary school children and young adults because of its easy availability and it is cheaper compared with most drugs of abuse. In Malaysia this problem has been recognized especially among the children in East Malaysia. In this study, 37 children and young adults from or around Kota Kinabalu, Sabah were referred to Bukit Padang Psychiatric Hospital by the Anti-drug Task force for suspected solvent abuse. These children were interviewed using questionaire and examined physically. Blood and urine were analysed for toluene and hippuric acid. 27 of the children, age ranging between 8 and 20 years, willingly admitted to sniffing glue for a period between a few months to 2 years. Most of them were children of Fillipino illegal immigrants in Kota Kinabalu. Biochemical parameters were found to be normal. Two of them were pale with low hemoglobin and 7 had eosinophilia. Haematuria and proteinuria were found in 21 children (78%). 16 blood samples with toluene levels ranging from 0.3 to 41 microg/ml and 10 urine samples have elevated urinary hippuric acid levels ranging from 1.2 to 7.4 mg/ml. Strong positive correlation was noted between mean blood toluene levels and duration of abuse.
authors.affiliation: Biochemistry Division, Institute for Medical Research, Kuala Lumpur. zabedah@imr.gov.my
authors.forename: M Y
authors.initials: MY
authors.lastname: Zabedah
authors.forename: M
authors.initials: M
authors.lastname: Razak
authors.forename: I
authors.initials: I
authors.lastname: Zakiah
authors.forename: A B
authors.initials: AB
authors.lastname: Zuraidah
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D006626:Hippurates / Q000097:blood / Q000652:urine; D006801:Humans; D008296:Malaysia / Q000453:epidemiology; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000503:physiopathology*; D014050:Toluene / Q000097:blood / Q000652:urine
chemical_list: D006626:Hippurates; D014050:Toluene; C030514:hippuric acid