title: Changing distribution of Candida species isolated from sterile and nonsterile sites in Israel.
abstract: To determine if the prevalence of non- albicans Candida spp. has increased at two institutions in Israel, the distribution of 6,954 Candida isolates obtained from sterile and nonsterile sites during the periods 1995-1996 and 1999-2000 were compared. In the latter period, a slight decrease was observed in the prevalence of non- albicans Candida spp. isolated from sterile sites (from 39% to 37%) and nonsterile sites (from 38% to 35%). Specifically, the prevalence of Candida glabrata increased significantly in sterile sites, from 26% to 35% (P=0.0095), and in nonsterile sites, from 18% to 27% (P<0.0001), and the prevalence of Candida krusei increased significantly in sterile sites, from 2% to 7% (P=0.0072). The prevalence of Candida parapsilosis decreased significantly in nonsterile sites, from 31% to 23% (P=0.0002). Continuous surveys of the distribution of Candida spp. and analysis of the clinical significance of changes are warranted.
authors.affiliation: Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. zsamra@clalit.org.il
authors.forename: Z
authors.initials: Z
authors.lastname: Samra
authors.forename: J
authors.initials: J
authors.lastname: Bishara
authors.forename: S
authors.initials: S
authors.lastname: Ashkenazi
authors.forename: S
authors.initials: S
authors.lastname: Pitlik
authors.forename: M
authors.initials: M
authors.lastname: Weinberger
authors.forename: M
authors.initials: M
authors.lastname: Lapidoth
authors.forename: M
authors.initials: M
authors.lastname: Yardeni
authors.forename: I
authors.initials: I
authors.lastname: Levy
mesh_terms: D002175:Candida / Q000145:classification* / Q000302:isolation & purification*; D002177:Candidiasis / Q000453:epidemiology* / Q000382:microbiology*; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D007557:Israel / Q000453:epidemiology; D015995:Prevalence; D013242:Sterilization