Electric fields induced in humans and rodents by 60 Hz magnetic fields.
Numerical computations are used to evaluate electric field dosimetry for high-resolution anatomically based inhomogeneous models of a human male child, and male and female rats and mice, under exposure to 60 Hz uniform magnetic field sources of three perpendicular orientations. The goal is to compare the child data to previously computed adult dosimetry and to evaluate the accuracy of linear scaling of organ dosimetry between species. It is expected that this work will aid in the design and interpretation of experiments involving rodents. It is found that child-to-adult and mouse-to-rat organ dosimetry shows the expected linear dependence on the geometric scale factor between models. The comparison between mice and the human child shows that postural and individual organ differences do have significant effects, and that care is required in scaling-based extrapolation of rodent experiment results to humans. However, for unrestrained animals, linear scaling appears to be a reasonable and conservative approach. Most of the rodent organ fields, for at least one field orientation, are greater than those expected from linear scaling.
Dawson
Trevor W
TW
Department of Electrical and Computer Engineering, University of Victoria, BC, Canada. tdawson@ece.uvic.ca
Caputa
Krys
K
Stuchly
Maria A
MA
D000328:Adult; D000375:Aging; D019412:Anatomy, Cross-Sectional / Q000379:methods*; D000818:Animals; D001824:Body Constitution; D002648:Child; D003198:Computer Simulation; D004574:Electromagnetic Fields; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008953:Models, Anatomic; D011874:Radiometry / Q000379:methods*; D051381:Rats; D012727:Sex Characteristics; D013045:Species Specificity