Marinosomes, marine lipid-based liposomes: physical characterization and potential application in cosmetics.
Marinosomes are liposomes based on a natural marine lipid extract containing a high polyunsaturated fatty acid (PUFA) ratio. They were prepared and characterized in conditions that mimic that of topical application in terms of pH, temperature and calcium. Marinosomes were stable in storage conditions for 1 month. At low pH (pH 4) or in presence of high calcium concentrations (9 mM), complex structural rearrangements, such as aggregation and size reduction, occurred which were kinetically dependant.
Moussaoui
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N
Laboratoire de Nutrition et Signalisation Cellulaire, ISTAB, Université Bordeaux I, Avenue des Facultés, F-33405 Cedex, Talence, France.
Cansell
M
M
Denizot
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A
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003358:Cosmetics / Q000032:analysis*; D005614:Freeze Fracturing; D008055:Lipids / Q000737:chemistry*; D008081:Liposomes; D018715:Microscopy, Video; D010316:Particle Size; D014677:Pharmaceutical Vehicles; D010713:Phosphatidylcholines / Q000737:chemistry; D010714:Phosphatidylethanolamines / Q000737:chemistry
D003358:Cosmetics; D008055:Lipids; D008081:Liposomes; D014677:Pharmaceutical Vehicles; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines