title: Trichoblastic neoplasm with apocrine differentiation.
abstract: Trichoblastoma is a benign neoplasm with primitive hair follicle differentiation. The tumor is characterized by nests and cords of epithelial cells in an organized relation to stroma. The epithelial cells differentiate toward follicular germ and follicular sheath. More divergent differentiation in the form of sebaceous elements in trichoblastoma has infrequently been reported in the literature. We report a trichoblastic neoplasm showing typical features of trichoblastoma as well as areas of apocrine differentiation. The neoplasm, which was present for several months, was removed from the chin of a 31-year-old woman. Histologic examination showed a neoplasm composed of basaloid nests with occasional papillary mesenchymal bodies as well as ducts and glands exhibiting apocrine differentiation. Trichoblastoma with apocrine features is rarely reported in the literature.
authors.affiliation: Ohio State University, University Medical Center, Columbus, Ohio, USA. arifsu@yahoo.com
authors.forename: Arif S
authors.initials: AS
authors.lastname: Usmani
authors.forename: Rana
authors.initials: R
authors.lastname: Rofagha
authors.forename: Adam B
authors.initials: AB
authors.lastname: Hessel
mesh_terms: D000328:Adult; D001050:Apocrine Glands / Q000473:pathology*; D002680:Chin; D005260:Female; D006201:Hair Diseases / Q000473:pathology*; D018859:Hair Follicle / Q000473:pathology*; D006801:Humans; D018294:Neoplasms, Adnexal and Skin Appendage / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome