title: Serious bradyarrhythmia that was possibly induced by lopinavir-ritonavir in 2 patients with acquired immunodeficiency syndrome.
abstract: We describe 2 patients with acquired immunodeficiency syndrome who had potentially fatal bradyarrhythmia that occurred shortly after commencement of antiretroviral therapy. Lopinavir-ritonavir was the only drug that both patients were using.
authors.affiliation: AIDS Clinical Center, International Medical Center of Japan, Tokyo.
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: Ikumi
authors.initials: I
authors.lastname: Genka
authors.forename: Azumi
authors.initials: A
authors.lastname: Ishizaki
authors.forename: Keishin
authors.initials: K
authors.lastname: Sunagawa
authors.forename: Akira
authors.initials: A
authors.lastname: Yasuoka
authors.forename: Shinichi
authors.initials: S
authors.lastname: Oka
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D019380:Anti-HIV Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001919:Bradycardia / Q000139:chemically induced*; D006801:Humans; D061466:Lopinavir; D008297:Male; D008875:Middle Aged; D011744:Pyrimidinones / Q000009:adverse effects* / Q000627:therapeutic use; D019438:Ritonavir / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D019380:Anti-HIV Agents; D011744:Pyrimidinones; D061466:Lopinavir; D019438:Ritonavir