[Clinico-pharmacologic activity of organic nitrates].
A summary of the published literature is presented together with findings from the author's investigations designed to study clinical-and-pharmacological properties of organic nitrates. The history is written up of discovery of a therapeutic effect of organic nitrates, pharmacokinetics, pharmacodynamics are described, indications for administration thereof are determined, ill effects of glycerol trinitrate (nitroglycerin), isosorbide dinitrate (nitrosorbide) and isosorbide-5-mononitrate (olicard) are described.
Chekman
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D006801:Humans; D009566:Nitrates / Q000494:pharmacology / Q000627:therapeutic use*; D009930:Organic Chemicals / Q000494:pharmacology / Q000627:therapeutic use*
D009566:Nitrates; D009930:Organic Chemicals