title: Liver slice technology as an in vitro model for metabolic and toxicity studies.
authors.affiliation: Department of Drug Metabolism and Pharmacokinetics, Astra Zeneca, Waltham, MA, USA.
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Thohan
authors.forename: Gerald M
authors.initials: GM
authors.lastname: Rosen
mesh_terms: D000818:Animals; D002470:Cell Survival; D002478:Cells, Cultured; D003374:Coumarins / Q000493:pharmacokinetics; D004210:Dissection / Q000379:methods; D066298:In Vitro Techniques; D007700:Kinetics; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008954:Models, Biological; D010477:Perfusion / Q000379:methods; D010634:Phenobarbital / Q000633:toxicity*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013385:Succinate Dehydrogenase / Q000032:analysis
chemical_list: D003374:Coumarins; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D010634:Phenobarbital