Characterization of ISRgn1, a novel insertion sequence of the IS3 family isolated from a bacteriocin-negative mutant of Ruminococcus gnavus E1.
ISRgn1, an insertion sequence of the IS3 family, has been identified in the genome of a bacteriocin-negative mutant of Ruminococcus gnavus E1. The copy number of ISRgn1 in R. gnavus E1, as well as its distribution among phylogenetically E1-related strains, has been determined. Results obtained suggest that ISRgn1 is not indigenous to the R. gnavus phylogenetic group but that it can transpose in this bacterium.
Gomez
Ana
A
Mixis France, Faculte de Medicine Necker-Enfants Malades, 75730 Paris Cedex 15, France. ana.gomez@mixis.fr
Ladire
Monique
M
Marcille
Francoise
F
Nardi
Michelle
M
Fons
Michel
M
D001421:Bacteria, Anaerobic / Q000235:genetics* / Q000378:metabolism; D001430:Bacteriocins / Q000378:metabolism*; D001483:Base Sequence; D004251:DNA Transposable Elements; D018628:Gene Dosage; D006094:Gram-Positive Bacteria / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D009154:Mutation; D017422:Sequence Analysis, DNA
D001430:Bacteriocins; D004251:DNA Transposable Elements