title: DEMETER, Goddess of the harvest, activates maternal MEDEA to produce the perfect seed.
abstract: Parental imprinting regulates processes as diverse as mammalian development and seed size in crop plants. In Arabidopsis, the DNA glycosylase DEMETER regulates early seed development, through activation of the maternal copy of the imprinted MEDEA Polycomb gene. Paternal silencing of MEA appears to be a default condition.
authors.affiliation: Department of Plant Sciences, University of Oxford, South Parks Road, United Kingdom.
authors.forename: Hugh
authors.initials: H
authors.lastname: Dickinson
authors.forename: Rod
authors.initials: R
authors.lastname: Scott
mesh_terms: D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics* / Q000254:growth & development; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D045647:DNA Glycosylases; D018506:Gene Expression Regulation, Plant; D018392:Genomic Imprinting; D009699:N-Glycosyl Hydrolases / Q000235:genetics / Q000378:metabolism*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D012639:Seeds / Q000201:enzymology / Q000235:genetics / Q000254:growth & development*; D015534:Trans-Activators
chemical_list: D029681:Arabidopsis Proteins; C111712:MEA protein, Arabidopsis; D010940:Plant Proteins; D015534:Trans-Activators; C463261:DEMETER protein, Arabidopsis; D045647:DNA Glycosylases; D009699:N-Glycosyl Hydrolases