title: Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989-1999.
abstract: We describe the annual incidence of primary bloodstream infection (BSI) associated with Candida albicans and common non-albicans species of Candida among patients in intensive care units that participated in the National Nosocomial Infections Surveillance system from 1 January 1989 through 31 December 1999. During the study period, there was a significant decrease in the incidence of C. albicans BSI (P<.001) and a significant increase in the incidence of Candida glabrata BSI (P=.05).
authors.affiliation: Health Outcomes Branch, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA. wbt9@cdc.gov
authors.forename: W E
authors.initials: WE
authors.lastname: Trick
authors.forename: S K
authors.initials: SK
authors.lastname: Fridkin
authors.forename: J R
authors.initials: JR
authors.lastname: Edwards
authors.forename: R A
authors.initials: RA
authors.lastname: Hajjeh
authors.forename: R P
authors.initials: RP
authors.lastname: Gaynes
mesh_terms: D000328:Adult; D002175:Candida / Q000302:isolation & purification*; D002177:Candidiasis / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D014481:United States / Q000453:epidemiology