Successful treatment of mother and baby with metastatic choriocarcinoma.
The second case of successful management of a mother and neonate with metastatic choriocarcinoma is described. A response to paclitaxel in the face of platinum-refractor disease in the mother is also detailed. In a woman with a history of gestational trophoblastic disease, a high index of suspicion and thereby early diagnosis lead to prompt treatment in both mother and neonate.
McNally
O M
OM
Department of Gynae-oncology, Ward 43, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, Scotland.
Tran
M
M
Fortune
D
D
Quinn
M A
MA
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy / Q000556:secondary; D002822:Choriocarcinoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D006063:Chorionic Gonadotropin / Q000097:blood; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000556:secondary; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary; D008297:Male; D017239:Paclitaxel / Q000008:administration & dosage; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*
D006063:Chorionic Gonadotropin; D005047:Etoposide; D017239:Paclitaxel