title: [Influence of age on myelogram in dogs].
abstract: The influence of age on the myelogram and on the different indices (ratios) was studied on bone marrow aspirates of 131 healthy dogs which were divided into different age groups (A [4-6 months] to G [> 8 years]). Myelograms were obtained by performing a differential count on 1000 cells. Age dependent differences were particularly seen in the 4 to 6 month old dogs. These dogs had significantly higher percentages of immature erythroid cells (p < 0.01) than dogs of the other age groups and, consequently, the lowest proportion of myeloid cells. This fact was also reflected by a lower quotient of number of myeloid cells/number of erythroid cells (M:E-ratio) and increased erythroid maturation index (I:ME-ratio). In addition, the proportions of monocytes and lymphocytes were increased and the number of plasma cells was decreased in juvenile dogs. The results in young dogs which were different from the values of adult animals reflect the increased requirements of red cell mass during the time of growth and ontogenesis of the immune system. These findings have to be considered in the interpretation of bone marrow films of young dogs.
authors.affiliation: Klinik für kleine Haustiere, Tierärztlichen Hochschule Hannover.
authors.forename: Reinhard
authors.initials: R
authors.lastname: Mischke
authors.forename: Ljuba
authors.initials: L
authors.lastname: Busse
authors.forename: Hans-Joachim
authors.initials: HJ
authors.lastname: Schuberth
mesh_terms: D000367:Age Factors; D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology*; D002452:Cell Count / Q000662:veterinary; D004285:Dogs / Q000502:physiology*; D004912:Erythrocytes / Q000166:cytology*; D009192:Myelography / Q000379:methods / Q000662:veterinary*; D022423:Myeloid Cells / Q000166:cytology