title: New structural perspectives on K(+) channel gating.
abstract: Ion channel gating is a two-stage process. It involves an initial energy transduction step, sensitive to a variety of physical stimuli (voltage, ligand binding, and tension), followed by the structural rearrangements that allow ion permeation. New structural data provides fresh information on both steps and offers unprecedented insight into how ion channels open and close at the molecular level.
authors.affiliation: Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22906, USA. eperozo@virginia.edu
authors.forename: Eduardo
authors.initials: E
authors.lastname: Perozo
mesh_terms: D019843:Archaeal Proteins / Q000737:chemistry / Q000378:metabolism; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D015640:Ion Channel Gating / Q000502:physiology*; D008954:Models, Biological; D015221:Potassium Channels / Q000737:chemistry / Q000378:metabolism*; D011487:Protein Conformation
chemical_list: D019843:Archaeal Proteins; D001426:Bacterial Proteins; D015221:Potassium Channels