title: Signal transduction. History matters.
authors.affiliation: Department of Molecular and Cellular Biology and Bauer Center for Genomics Research, Harvard University, Cambridge, MA 02138, USA.
authors.forename: Nicholas T
authors.initials: NT
authors.lastname: Ingolia
authors.forename: Andrew W
authors.initials: AW
authors.lastname: Murray
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D005075:Biological Evolution; D018797:Cell Cycle Proteins; D002478:Cells, Cultured; D054638:Dual Specificity Phosphatase 1; D025461:Feedback, Physiological; D017874:Immediate-Early Proteins / Q000378:metabolism*; D020935:MAP Kinase Signaling System; D020928:Mitogen-Activated Protein Kinases / Q000378:metabolism*; D008954:Models, Biological; D010749:Phosphoprotein Phosphatases; D010982:Platelet-Derived Growth Factor / Q000378:metabolism / Q000494:pharmacology; D054645:Protein Phosphatase 1; D017027:Protein Tyrosine Phosphatases / Q000378:metabolism*
chemical_list: D018797:Cell Cycle Proteins; D017874:Immediate-Early Proteins; D010982:Platelet-Derived Growth Factor; D020928:Mitogen-Activated Protein Kinases; D010749:Phosphoprotein Phosphatases; D054645:Protein Phosphatase 1; D054638:Dual Specificity Phosphatase 1; D017027:Protein Tyrosine Phosphatases