[Effect of intercalators on the properties of liquid-crystalline dispersions of nucleic acid-chitosan complex].
Molecules of deoxyribonucleic acid and synthetic polydeoxyribonucleotides (NA) in the particles of liquid-crystalline dispersions resulting from interaction with chitosan are accessible to interaction with intercalators. The intercalation is accompanied by alteration in the direction of spatial twist of cholesterics of NA-chitosan complexes. This effect is absent in the case of "classical" cholesterics produced from NA molecules via phase exclusion, i.e., the cholesteric structure of NA-chitosan complex is very "labile" as distinct from "classical" cholesteric NA.
Salianov
V I
VI
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia.
Il'ina
A V
AV
Varlamov
V P
VP
Evdokimov
Iu M
IuM
D002686:Chitin / Q000031:analogs & derivatives* / Q000737:chemistry*; D048271:Chitosan; D002942:Circular Dichroism; D003460:Crystallization; D003630:Daunorubicin / Q000737:chemistry; D007364:Intercalating Agents / Q000737:chemistry*; D008942:Mitoxantrone / Q000737:chemistry; D009696:Nucleic Acids / Q000737:chemistry*; D011089:Polydeoxyribonucleotides / Q000737:chemistry
D007364:Intercalating Agents; D009696:Nucleic Acids; D011089:Polydeoxyribonucleotides; D002686:Chitin; D048271:Chitosan; D008942:Mitoxantrone; D003630:Daunorubicin