title: Irritant potential of triterpenoids from Ficus carica leaves.
abstract: The irritant potential of total methanolic extract and five triterpenoids newly isolated from the leaves of Ficus carica investigated by open mouse ear assay. Total methanolic extract, calotropenyl acetate, methyl maslinate and lupeol acetate showed potent and persistent irritant effects.
authors.affiliation: Department of Pharmacy, University of the Punjab (Allama Iqbal Campus), 54000, Lahore, Pakistan. moasif1605@hotmail.com
authors.forename: M Asif
authors.initials: MA
authors.lastname: Saeed
authors.forename: A W
authors.initials: AW
authors.lastname: Sabir
mesh_terms: D000818:Animals; D005260:Female; D030681:Ficus / Q000737:chemistry*; D007509:Irritants / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D051379:Mice; D018515:Plant Leaves / Q000737:chemistry*; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D007509:Irritants; D014315:Triterpenes