Chemotherapeutic agents against malaria: what next after chloroquine?
This is a general review of currently available antimalarial drugs, these compounds are gathered according with its chemical structure and the biological targets. A great number of these new antimalarial agents are now moving actively in the pipeline from basic science to clinical studies.
Domínguez
José N
JN
Universidad Central de Venezuela, Facultad de Farmacia. Laboratorio de Síntesis Orgánica, Caracas, 1051, Venezuela. dominguj@camelot.rect.ucv.ve
D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D037621:Artemisinins / Q000627:therapeutic use; D001685:Biological Factors / Q000627:therapeutic use; D002738:Chloroquine / Q000627:therapeutic use*; D005493:Folic Acid Antagonists / Q000627:therapeutic use; D006801:Humans; D008288:Malaria / Q000188:drug therapy*; D011480:Protease Inhibitors / Q000627:therapeutic use; D011803:Quinine / Q000031:analogs & derivatives / Q000627:therapeutic use; D012717:Sesquiterpenes / Q000627:therapeutic use
D000962:Antimalarials; D037621:Artemisinins; D001685:Biological Factors; D005493:Folic Acid Antagonists; D011480:Protease Inhibitors; D012717:Sesquiterpenes; D002738:Chloroquine; C031327:artemisinin; D011803:Quinine