Fibrosing mediastinitis secondary to zygomycosis in a twenty-two-month-old child.
We report the case of a 22-month-old immunocompetent male child with fibrosing mediastinitis secondary to zygomycosis, an unusual presentation of a rare fungal infection. This patient was successfully treated with amphotericin B and itraconazole for 20 weeks. Stenting of the superior vena cava was helpful in relieving the patient's superior vena cava syndrome.
Robertson
Brian D
BD
Department of Pediatrics, San Antonio Military Pediatric Center, Lackland Air Force Base, TX 78236-5300, USA. brian.robertson@lackland.af.mil
Bautista
Matt A
MA
Russell
Tod S
TS
Naclerio
Anne L
AL
Porisch
Mary E
ME
Sorrells
Donald L
DL
Fiser
Richard T
RT
D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D005355:Fibrosis; D006801:Humans; D007223:Infant; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D008480:Mediastinitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D015607:Stents; D013479:Superior Vena Cava Syndrome / Q000188:drug therapy / Q000601:surgery; D016896:Treatment Outcome; D020096:Zygomycosis / Q000150:complications* / Q000188:drug therapy
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B