[Squamous cell carcinoma of the renal pelvis after intrarenal bacillus Calmette-Guerin therapy for carcinoma in situ of upper urinary tract: a case report].
A 73-year-old man was admitted with high fever. Histopathologically, he was diagnosed with transitional cell carcinoma in situ (CIS) of bilateral upper urinary tracts and urinary bladder in April, 1995. Double J shape ureteral catheter was placed in the left ureter to induce vesicoureteral reflux and Bacillus Calmette-Guerin (BCG) was instilled intravesically every week. Then, the same procedure was performed on the other side. Unfortunately, the treatments could not be completed due to severe complications (high fever and renal dysfunction). Follow-up studies revealed that the left kidney had lost function and right upper urinary tract still had CIS. Therefore, right nephroureterectomy was performed for right renal pelvic cancer (TCC, G3, pT1) followed by permanent hemodialysis in September, 1996. Invasive bladder cancer arose in the abandoned bladder and cystourethrectomy and left ureterocutaneostomy was performed in September, 1999. In April 2000, imaging studies revealed a renal pelvic tumor in his left kidney and left nephroureterectomy was performed. Histopathological diagnosis was squamous cell carcinoma of the left renal pelvis.
Uemura
Motohide
M
Department of Urology, Osaka Rosai Hospital.
Mukai
Masatoshi
M
Fukuhara
Shinichiro
S
Kanno
Nobufumi
N
Nishimura
Kensaku
K
Miyoshi
Susumu
S
Yoshida
Kyotaro
K
Kawano
Kiyoshi
K
Inoue
Hitoshi
H
Nishimura
Kazuo
K
D000368:Aged; D001500:BCG Vaccine / Q000009:adverse effects* / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D002295:Carcinoma, Transitional Cell / Q000628:therapy*; D006801:Humans; D007680:Kidney Neoplasms / Q000209:etiology*; D007682:Kidney Pelvis; D008297:Male; D016609:Neoplasms, Second Primary / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000628:therapy*
D001500:BCG Vaccine