Isolation and identification of oligomeric procyanidins from Crataegus leaves and flowers.
Oligomeric procyanidins were isolated from the leaves and flowers of hawthorn (Crataegus laevigata). A trimer, epicatechin-(4 beta-->8)-epicatechin-(4 beta-->6)-epicatechin, and a pentamer consisting of (-)-epicatechin units linked through C-4 beta/C-8 bonds have been isolated from hawthorn for the first time, in addition to known procyanidins including dimers B-2, B-4 and B-5, trimers C-1 and epicatechin-(4 beta-->6)-epicatechin-(4 beta-->8)-epicatechin, and tetramer D-1. A fraction containing a hexamer was also found.
Svedström
Ulla
U
Department of Pharmacy, Division of Pharmacognosy, University of Helsinki, PO Box 56, FIN-00014 Helsinki, Finland.
Vuorela
Heikki
H
Kostiainen
Risto
R
Tuominen
Jari
J
Kokkonen
Juha
J
Rauha
Jussi-Pekka
JP
Laakso
Into
I
Hiltunen
Raimo
R
D044946:Biflavonoids; D002392:Catechin / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D027825:Crataegus / Q000737:chemistry*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D044945:Proanthocyanidins; D021241:Spectrometry, Mass, Electrospray Ionization
D044946:Biflavonoids; D044945:Proanthocyanidins; C017674:procyanidin; D002392:Catechin