Congenital dyserythropoietic anaemia type II: a case study.
A 13-year-old girl with chronic anaemia showed features of congenital dyserythropoietic anaemia (CDA) type II. The main clinical and haematological findings were splenomegaly, a mild microcytic anaemia, and numerous bizarre and binucleate normoblasts in the bone marrow. The acidified serum lysis test (Ham's test) performed with 5 normal sera was positive. The patient's red blood cells showed a markedly increased expression of the i red blood cell antigen.
De Laere
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Laboratorium Hematologie, A.Z. Sint-Jan, Ruddershove 10, B-8000 Brugge.
Louwagie
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Criel
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A
D000293:Adolescent; D000742:Anemia, Dyserythropoietic, Congenital / Q000175:diagnosis* / Q000235:genetics; D005260:Female; D006801:Humans