title: Quantifying sodium in the human wrist in vivo by using MR imaging.
abstract: The authors quantified sodium content in the wrist joints of six healthy volunteers with no known history of arthritis or pain. Average sodium concentrations ranged from 115 to 150 mmol/L in noncartilaginous regions and from 200 to 210 mmol/L in cartilaginous regions. The feasibility of quantifying sodium in vivo was demonstrated. This method has potential applications in monitoring the integrity of cartilaginous tissue in vivo.
authors.affiliation: Department of Radiology, University of Pennsylvania, B1 Stellar-Chance Laboratories, 422 Curie Blvd, Philadelphia, PA 19104-6100, USA. ari@mail.mmrrcc.upenn.edu
authors.forename: Arijitt
authors.initials: A
authors.lastname: Borthakur
authors.forename: Erik M
authors.initials: EM
authors.lastname: Shapiro
authors.forename: Sarma V S
authors.initials: SV
authors.lastname: Akella
authors.forename: Alexander
authors.initials: A
authors.lastname: Gougoutas
authors.forename: J Bruce
authors.initials: JB
authors.lastname: Kneeland
authors.forename: Ravinder
authors.initials: R
authors.lastname: Reddy
mesh_terms: D000328:Adult; D002358:Cartilage, Articular / Q000737:chemistry*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011509:Proteoglycans / Q000032:analysis; D012964:Sodium / Q000032:analysis*; D014955:Wrist Joint / Q000737:chemistry*
chemical_list: D011509:Proteoglycans; D012964:Sodium