Unexpected findings in identifiable stored blood samples after analysis without consent: moral arguments for and against disclosure.
Obtaining informed consent for using blood samples in research is mandatory. However, sometimes no consent is obtained for analysis of identifiable blood samples in a second study. As a result, a moral dilemma raises in case a possibly pathogenic mutation is found. Should the involved person be informed that such a mutation has been detected? We present a case in which this problem occurred and discuss arguments for and against information disclosure.
Verweij
M F
MF
Department of Ethics, Philosophy and History of Medicine, University Medical Center Nijmegen, The Netherlands.
Hamel
B C J
BC
D000328:Adult; D001782:Blood Donors; D006332:Cardiomegaly / Q000097:blood / Q000235:genetics*; D032984:Ethics, Research; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007258:Informed Consent; D009154:Mutation; D014342:Truth Disclosure
Biomedical and Behavioral Research; Genetics and Reproduction