Purification of an Antineurotoxic Factor from Serum of Snake Bungarus multicinctus.
An antineurotoxic factor has been purified from the serum of the snake B. multicinctus. The purified antineurotoxic factor shows a single band in PAGE and SDS-PAGE, running in the region of alpha(2)- or beta-globulin. This antineruotoxic factor is a glycoprotein and its molecular weight is (80+-5) kD. This antineurotoxic factor can partially neutralize the toxicity of beta-BuTx and possesses inhibition activity to the beta-BuTx PLA(2) enzyme.
Shen
Yan-Qin
YQ
Department of Biochemistry, Zhejiang Medical University, Hangzhou 310031, China.
Shao
Jing-Yu
JY