New triterpenoids from the leaves of Abrus precatorius.
Three new (1-3) triterpenoids and one known (4) triterpenoid were isolated from an acid hydrolyzed methanol-soluble extract of the leaves of Abrus precatorius. Their structures were identified as (20S,22S)-3beta,22-dihydroxycucurbita-5(10),24-diene-26,29-dioic acid delta-lactone (1), 3-O-[6'-methyl-beta-D-glucuronopyranosyl]-3beta,22beta-dihydroxyolean-12-en-29-oic acid methyl ester (2), 3-O-beta-D-glucuronopyranosylsophoradiol methyl ester (3), and sophoradiol (4) by spectroscopic techniques including 2D NMR.
Kim
Nam-Cheol
NC
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612, USA.
Kim
Darrick S H L
DS
Kinghorn
A Douglas
AD
D029912:Abrus / Q000737:chemistry*; D005431:Florida; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D012503:Saponins; D017550:Spectroscopy, Fourier Transform Infrared; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
C469878:(20S,22S)-3beta,22-dihydroxycucurbita-5(10),24-diene-26,29-dioic acid delta-lactone; C469879:3-O-(6'-methyl-beta-D-glucuronopyranosyl)-3beta,22beta-dihydroxyolean-12-en-29-oic acid methyl ester; C469880:3-O-glucuronopyranosylsophoradiol methyl ester; D012503:Saponins; D014315:Triterpenes; C410446:abrusoside A methyl ester; C417684:sophoradiol; D009828:Oleanolic Acid