title: Gabapentin treatment of glossopharyngeal neuralgia: a follow-up of four years of a single case.
abstract: Glossopharyngeal neuralgia causes intermittent, lancinanting pain, involving the posterior tongue and pharynx, with radiation to deep ear structures. There are different pharmacological therapies which are tried to treat the neuralgia: carbamazepin, phenytoin, diazepam, amytriptyline, phenobarbital, ketamine, and baclofen; there are also surgical treatment proposed in order to cure the neuralgia such as vascular decompression or electrical stimulation of the motor cortex controlateral to the pain area. We report a single case of a patient with glossopharyngeal neuralgia treated with Gabapentin, the first described, who was followed up for four years, who respond completely to the therapy and did not complain from side effects, reducing even the reminiscence of pain during the second cluster of crisis.
authors.affiliation: Dipartimento di Fisiologia e Patologia, Università degli Studi di Trieste, Italy. moretti@univ.trieste.it
authors.forename: Rita
authors.initials: R
authors.lastname: Moretti
authors.forename: Paola
authors.initials: P
authors.lastname: Torre
authors.forename: R M
authors.initials: RM
authors.lastname: Antonello
authors.forename: Antonio
authors.initials: A
authors.lastname: Bava
authors.forename: G
authors.initials: G
authors.lastname: Cazzato
mesh_terms: D000085:Acetates / Q000627:therapeutic use*; D000588:Amines; D000700:Analgesics / Q000627:therapeutic use*; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000927:Anticonvulsants / Q000009:adverse effects; D002220:Carbamazepine / Q000009:adverse effects; D003509:Cyclohexanecarboxylic Acids; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D000077206:Gabapentin; D005930:Glossopharyngeal Nerve / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D020435:Glossopharyngeal Nerve Diseases / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D014147:Tramadol / Q000627:therapeutic use; D016896:Treatment Outcome; D005680:gamma-Aminobutyric Acid
chemical_list: D000085:Acetates; D000588:Amines; D000700:Analgesics; D000701:Analgesics, Opioid; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D002220:Carbamazepine; D014147:Tramadol; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin