[Prostatic adenocarcinoma revealed by disseminated intravascular coagulation and fibrinolysis].
Disseminated intravascular coagulation (DIC) revealing a prostatic adenocarcinoma is rare. Most of the case are limited to biological abnormalities. We report a case of a 73 year old man with metastatic prostatic carcinoma and CIVD. The patient consulted for epistaxis and ecchymosis with thrombocytopenia and low coagulate factors. The prostatic specific antigen was 2200 ng/ml and fine needle aspiration of bone marrow biopsy detected metastatic cells. The patients received hormonotherapy, heparine and antithrombine III with a good follow up. About this case, we discuss the management of the patient with metastatic prostatic cancer and CIVD.
Rabii
R
R
Service d'urologie, hôpital Henri Mondor, 51, avenue du Maréchal de Lattre de Tassigny, 94010 Créteil, France. rrabii@urologues.com
Salomon
L
L
Hodznek
A
A
Saint
F
F
Cicco
A
A
Chopin
D K
DK
Abbou
C C
CC
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis* / Q000556:secondary; D000368:Aged; D000726:Androgen Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D000990:Antithrombin III / Q000008:administration & dosage / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000556:secondary; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005342:Fibrinolysis; D005500:Follow-Up Studies; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007279:Injections, Subcutaneous; D016729:Leuprolide / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D011471:Prostatic Neoplasms / Q000150:complications / Q000175:diagnosis*; D013249:Sternum; D013997:Time Factors
D000726:Androgen Antagonists; D000925:Anticoagulants; D000990:Antithrombin III; D006493:Heparin; D016729:Leuprolide