title: Chromatin: a connection between loops and barriers?
abstract: A genetic screen for proteins that can block the spread of silenced heterochromatin has identified components of the nuclear pores with potential barrier activity. These results suggest that formation of loops of chromatin anchored to the pore could be one mechanism of barrier function.
authors.affiliation: Unit on Chromatin and Transcription, NICHD/NIH, Bldg. 18T, Rm. 106, 18 Library Drive, Bethesda, MD 20892, USA. Rohinton@helix.nih.gov
authors.forename: Rohinton T
authors.initials: RT
authors.lastname: Kamakaka
mesh_terms: D002843:Chromatin / Q000235:genetics*; D015825:Chromosomes, Fungal / Q000235:genetics; D015966:Gene Expression Regulation, Fungal; D020868:Gene Silencing; D006570:Heterochromatin / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D016615:Telomere / Q000235:genetics
chemical_list: D002843:Chromatin; D006570:Heterochromatin