title: Risk assessment of virus-resistant transgenic plants.
abstract: Virus-resistant transgenic plants (VRTPs) hold the promise of enormous benefit for agriculture. However, over the past ten years, questions concerning the potential ecological impact of VRTPs have been raised. In some cases, detailed study of the mode of action of the resistance gene has made it possible to eliminate the source of potential risk, notably the possible effects of heterologous encapsidation on the transmission of viruses by their vectors. In other cases, the means of eliminating likely sources of risk have not yet been developed. When such residual risk still exists, the potential risks associated with the VRTP must be compared with those associated with nontransgenic plants so that risk assessment can fully play its role as part of an overall analysis of the advantages and disadvantages of practicable solutions to the problem solved by the VRTP.
authors.affiliation: Laboratoire de Biologie Cellulaire, INRA-Versailles, F-78026 Versailles cedex, France. Mark.Tepfer@versailles.inra.fr
authors.forename: Mark
authors.initials: M
authors.lastname: Tepfer
mesh_terms: D017796:Caulimovirus / Q000235:genetics / Q000254:growth & development; D004463:Ecology; D005816:Genetic Complementation Test; D005822:Genetic Vectors / Q000235:genetics; D007113:Immunity, Innate / Q000235:genetics; D010641:Phenotype; D010935:Plant Diseases / Q000235:genetics / Q000821:virology*; D010942:Plant Viruses / Q000235:genetics / Q000254:growth & development*; D030821:Plants, Genetically Modified / Q000821:virology*; D011995:Recombination, Genetic; D018570:Risk Assessment; D013045:Species Specificity