[Paraquat poisoning and hemoperfusion with activated charcoal].
Paraquat is a common herbicide in Spain. In our country there are a few cases of this intoxication and it presents a high mortality even if the patients ingest a minimal amount. We present two cases of accidental poisoning with paraquat. These patients were admitted three hours after ingestion of toxin. They were treated with with orogastric lavage, activated charcoal, N-acetylcysteine, Fuller's earth, cathartics, support measures and hemoperfusion with activated charcoal. With these treatments both patients had a undetectable levels of paraquat 48 hours after and improvement of their symptoms, gastric and intestinal predominantly . We present the graphics of evolution of the plasma and urine levels of paraquat in both patients. We review the different aspects of treatment and update of this poisoning.
López Lago
A M
AM
Servicio de Medicina Intensiva, Hospital Clínico Universitario de Santiago de Compostela.
Rivero Velasco
C
C
Galban Rodríguez
C
C
Mariño Rozados
A
A
Piñeiro Sande
N
N
Ferrer Vizoso
E
E
D000059:Accidents; D000111:Acetylcysteine / Q000627:therapeutic use; D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use; D002400:Cathartics / Q000627:therapeutic use; D002606:Charcoal / Q000627:therapeutic use*; D007692:Diatomaceous Earth / Q000627:therapeutic use*; D005260:Female; D005440:Fluid Therapy; D005751:Gastric Lavage; D005947:Glucose / Q000627:therapeutic use; D006464:Hemoperfusion; D006801:Humans; D008297:Male; D008875:Middle Aged; D010269:Paraquat / Q000097:blood / Q000506:poisoning* / Q000652:urine; D011041:Poisoning / Q000628:therapy
D000975:Antioxidants; D002400:Cathartics; D002606:Charcoal; D007692:Diatomaceous Earth; D005947:Glucose; D010269:Paraquat; D000111:Acetylcysteine