title: Tumor lysis syndrome following endoscopic radiofrequency interstitial thermal ablation of colorectal liver metastases.
abstract: Radiofrequency interstitial thermal ablation (RITA) provides a palliative option for patients suffering from metastatic liver disease. This procedure can be performed using a laparoscopic approach with laparoscopic ultrasound used to position the RITA probe. We describe a case of laparoscopic RITA performed for colorectal liver metastasis that was complicated by tumor lysis syndrome (TLS) following treatment. We consider RITA to be a safe procedure, as supported by the literature, but where intracorporal tumor lysis is the treatment goal we believe that the systemic release of tumor products can overwhelm the excretory capacity; therefore, TLS is an inevitable consequence in some patients.
authors.affiliation: Department of Surgery, Cork University Hospital, University College Cork, Cork, Ireland.
authors.forename: B D
authors.initials: BD
authors.lastname: Barry
authors.forename: M R
authors.initials: MR
authors.lastname: Kell
authors.forename: H P
authors.initials: HP
authors.lastname: Redmond
mesh_terms: D000328:Adult; D017115:Catheter Ablation / Q000009:adverse effects* / Q000379:methods; D002430:Cecal Neoplasms / Q000473:pathology / Q000601:surgery; D003082:Colectomy; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery*; D004724:Endoscopy / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000473:pathology / Q000601:surgery; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology*; D015275:Tumor Lysis Syndrome / Q000209:etiology*