The link between psychosocial factors and functional dyspepsia: an epidemiological study.
OBJECTIVE
To investigate the prevalence of functional dyspepsia (FD) and the psychological disorders in Chinese population and their relation.


METHODS
A total of 1016 apparently healthy people (study population) randomly selected from population were interviewed. A general questionnaire, Zung self-rating depression scales (SDS), and anxiety scales (SAS) were given to each subject. Seventy-two inpatients with confirmed diagnosis of FD, 84 with organic dyspepsia, and 197 with other organic diseases were also studied.


RESULTS
Among the study population, 23.5% had FD and 9. 1% had disturbances of depression and/or anxiety. The prevalence of psychological disturbances in FD group (15.5%) differed significantly from that in non-FD group (7.1%, P < 0.01 ) . In the survey of inpatients, the rate of depression/anxiety in FD group (54.2%) was greater than that in organic dyspepsia group (19.0%) and other organic diseases group (28.9%), P < 0.05, and was also significantly higher than that of the FD cases in the study population (15.5%), P < 0.01. Further analysis showed that some psychosocial disturbances were risk factors of FD.


CONCLUSIONS
Both FD and depression/anxiety disturbances are common in China, and there is a link between them.
Li
Yuyuan
Y
Division of Gastroenterology, First Municipal People's Hospital of Guangzhou, Guangzhou 510180, China. liyyliyy@163.net
Nie
Yuqiang
Y
Sha
Weihong
W
Su
Hua
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology*; D004415:Dyspepsia / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000453:epidemiology; D015995:Prevalence