title: [A case of pulmonary thromboembolism after interruption of treatment with unfractionated heparin].
abstract: Pulmonary embolism is a quite frequent event (incidence 1/10000/year), and blood stasis, endothelial lesions and coagulation disorders are predisposable factors. Elective treatment is heparin, but the use of this medication is associated with a possible ipercoagulative rebound effect. The case presented is a patient with unstable angina treated with heparin infusion, who developed pulmonary embolism after discontinuation of heparin treatment; the patient didn't present a genetic coagulopathy. Others risk factors have been analyzed and it was observed that discontinuation of heparin infusion could have a predominant role in the development of thrombosis. A MedLine research on the rebound effect of heparin and how to reduce it has been carried out.
authors.affiliation: Cardiologia Universitaria, Ospedale San Giovanni Battista di Torino, Università degli Studi di Torino, Turin, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Paglia
authors.forename: L
authors.initials: L
authors.lastname: Carrieri
authors.forename: E
authors.initials: E
authors.lastname: Oliaro
authors.forename: S
authors.initials: S
authors.lastname: Bergerone
authors.forename: L
authors.initials: L
authors.lastname: Mangiardi
authors.forename: G P
authors.initials: GP
authors.lastname: Trevi
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage*; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D011655:Pulmonary Embolism / Q000209:etiology* / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D006493:Heparin