The Colorado mental retardation and developmental disabilities research center.
The Colorado MRRC was one of the original MRRCs funded and has maintained its focus on genetic and nutritional causes of mental retardation and developmental disabilities. Significant discoveries of the center have included a number of metabolic disorders, including glutaric academia types I and II, electron transport flavoprotein (ETF) deficiency, ETF dehydrogenase deficiency, glycerol kinase deficiency, sphingolipidoses, genetic linkages in dyslexia, phonological deficits in dyslexia, and the importance of the trace mineral Zn in early development. Current research at the center is supported by program of projects grants on inborn errors of metabolism, Down syndrome (DS), autism, and dyslexia.
Crnic
Linda S
LS
B.F. Stolinsky Research Laboratories, Science Center, University of Colorado Health, Denver, CO 80262, USA. linda.crnic@uchsc.edu
D000046:Academic Medical Centers / Q000458:organization & administration / Q000639:trends*; D000818:Animals; D035843:Biomedical Research; D001921:Brain / Q000378:metabolism / Q000503:physiopathology*; D002648:Child; D003120:Colorado; D002658:Developmental Disabilities / Q000209:etiology* / Q000503:physiopathology; D004195:Disease Models, Animal; D006801:Humans; D008607:Intellectual Disability / Q000209:etiology* / Q000503:physiopathology; D033183:Interdisciplinary Communication