Spasmolytic activity of Toddalia asiatica Var. floribunda.
The spasmolytic activity of the aerial parts of Toddalia asiatica var. floribunda (family Rutaceae) was evaluated. The ethanol extract exhibited significant spasmolytic activity and was then partitioned into five fractions. The activity was found to be concentrated only in the hexane and chloroform fractions. This activity was shown not to be due to the coumarins, toddalolactone and toddanone, as was previously thought.
Lakshmi
V
V
Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow, India.
Kapoor
S
S
Pandey
K
K
Patnaik
G K
GK
D000818:Animals; D005260:Female; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects* / Q000503:physiopathology; D066298:In Vitro Techniques; D008297:Male; D010276:Parasympatholytics / Q000494:pharmacology* / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D027821:Rutaceae; D013035:Spasm / Q000503:physiopathology / Q000517:prevention & control
D010276:Parasympatholytics; D010936:Plant Extracts