title: Enamel fluoride uptake from mouthrinse solutions with different NaF concentrations.
abstract: OBJECTIVE
  The influence on enamel fluoride uptake of reducing the NaF concentration of a mouthrinse solution by half, from 0.05-0.025%, was examined in elementary school children.
  
  
  METHODS
  The participatory elementary school had employed school-based fluoride mouthrinse with 0.05% NaF solution since 1983, and in 1993, the NaF content was lowered to 0.025%. Dental examination and enamel biopsy of maxillary central incisors were performed just before the NaF content reduction for children who had received the daily 0.05% NaF mouthrinse for 2-5 years since 6 years of age. During 1993-95, dental examination and enamel biopsy were undertaken for newly enrolled 6-year-old children, and the same subjects were re-examined after 2 years. The same series of examinations were conducted for the control group, which consisted of children belonging to another elementary school without a fluoride program.
  
  
  RESULTS
  The enamel fluoride concentration of 8-year-old children who used the 0.025% NaF mouthrinse for 2 years was 1810 +/- 535 ppm, reaching the same order as that in children who continued using the 0.05% NaF mouthrinse (1863 +/- 1358 ppm), and was significantly higher than that of children without fluoride programs (1113 +/- 303 ppm). There was no considerable increase of mean DMFT values due to the NaF content reduction.
  
  
  CONCLUSIONS
  It was concluded that a daily 0.025% NaF mouthrinse provides the similar fluoride content for enamel as 0.05% NaF mouthrinse as long as the rinsing frequency is maintained.
authors.affiliation: Department of Preventive Dentistry, Iwate Medical University School of Dentistry, Morioka, Japan. dinaba@iwate-med.ac.jp
authors.forename: Daisuke
authors.initials: D
authors.lastname: Inaba
authors.forename: Koji
authors.initials: K
authors.lastname: Kawasaki
authors.forename: Youichi
authors.initials: Y
authors.lastname: Iijima
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Taguchi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Hayashida
authors.forename: Tadashi
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Reiko
authors.initials: R
authors.lastname: Furugen
authors.forename: Emiko
authors.initials: E
authors.lastname: Fukumoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishiyama
authors.forename: Keiko
authors.initials: K
authors.lastname: Tanaka
authors.forename: Okiuji
authors.initials: O
authors.lastname: Takagi
mesh_terms: D000704:Analysis of Variance; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000453:epidemiology / Q000517:prevention & control; D003743:Dental Enamel / Q000378:metabolism*; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D009067:Mouthwashes / Q000737:chemistry*; D015995:Prevalence; D012969:Sodium Fluoride / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D018709:Statistics, Nonparametric
chemical_list: D009067:Mouthwashes; D012969:Sodium Fluoride