title: Sno-capped: 5' ends of preribosomal RNAs are decorated with a U3 SnoRNP.
abstract: Efficient ribosome biosynthesis is crucial for cell viability. Work recently published in Nature demonstrates that a large ribonucleoprotein processes 18S rRNA in S. cerevisiae, indicating that macromolecular particles regulate ribosome maturation and revealing the complex nature of this process.
authors.affiliation: Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA.
authors.forename: Gloria M
authors.initials: GM
authors.lastname: Culver
mesh_terms: D002466:Cell Nucleolus / Q000378:metabolism; D046911:Macromolecular Substances; D012335:RNA, Ribosomal / Q000096:biosynthesis* / Q000737:chemistry; D020537:RNA, Small Nucleolar / Q000378:metabolism; D020718:Ribonucleoproteins, Small Nucleolar / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
chemical_list: D046911:Macromolecular Substances; D012335:RNA, Ribosomal; D020537:RNA, Small Nucleolar; C117378:RNA, U3 small nucleolar; D020718:Ribonucleoproteins, Small Nucleolar; D029701:Saccharomyces cerevisiae Proteins; C117377:ribonucleoprotein, U3 small nucleolar