Coexistence of inversion 16 and the Philadelphia chromosome in patients with acute myelogenous leukemia.
The coexistence of the Philadelphia chromosome and inversion 16 abnormality in de novo acute myelogenous leukemia (AML) has only rarely been reported. We report the case of a 23-year-old man with these cytogenetic abnormalities. He is in a durable remission following intensive chemotherapy. The literature on this subject is reviewed.
Siddiqui
Ahmad D
AD
Zalmen A. Arlin Cancer Institute and Department of Medicine, New York Medical College, Valhalla 10595, USA.
Sheikh
Zahra S
ZS
Liu
Delong
D
Seiter
Karen
K
D000328:Adult; D007446:Chromosome Inversion; D002885:Chromosomes, Human, Pair 16; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D010677:Philadelphia Chromosome