In vivo veritas: in vitro macrolide resistance in systemic Streptococcus pneumoniae infections does result in clinical failure.
Jacobs
Michael R
MR
D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D016470:Bacteremia / Q000150:complications / Q000378:metabolism; D017714:Community-Acquired Infections / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D003362:Cost-Benefit Analysis; D004351:Drug Resistance; D006801:Humans; D018942:Macrolides; D008826:Microbial Sensitivity Tests; D011018:Pneumonia, Pneumococcal / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D012720:Severity of Illness Index; D013296:Streptococcus pneumoniae / Q000187:drug effects; D017211:Treatment Failure
D000900:Anti-Bacterial Agents; D018942:Macrolides