title: Peroxynitrite scavenging activities of aromatic compounds isolated from Konnyaku, Amorphophallus konjac K.Koch.
abstract: (+/-)-5,5'-Dimethoxysesamin, erythrinasinate, indole-3-carbaldehyde, (7R,8S)-dihydrodehydrodiconiferyl alcohol 9-O-beta-D-glucopyranoside, cis- and trans-N-(p-coumaroyl)serotonin, serotonin, 3,4-dihydroxybenzoic acid, and 3,4-dihydroxybenzaldehyde have been found in tobiko, a food by-product, and evaluation of their peroxynitrite scavenging activities has been done. Among these compounds, serotonin, trans-N-(p-coumaroyl)serotonin, 3,4-dihydroxybenzaldehyde, and 3,4-dihydroxybenzoic acid showed stronger activities than that of BHT (butylated hydroxytoluene) at 200 microM.
authors.affiliation: The United Graduate School of Agricultural Sciences, Gifu University, Shizuoka, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Niwa
authors.forename: Kazushi
authors.initials: K
authors.lastname: Murakami
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Ohtake
authors.forename: Hideo
authors.initials: H
authors.lastname: Etoh
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shimizu
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Yoji
authors.initials: Y
authors.lastname: Kato
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tanaka
mesh_terms: D031056:Amorphophallus / Q000737:chemistry* / Q000378:metabolism*; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D006571:Heterocyclic Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism*; D015394:Molecular Structure; D030421:Peroxynitrous Acid / Q000378:metabolism*
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D006571:Heterocyclic Compounds; D030421:Peroxynitrous Acid