title: A case of seborrheic blepharitis; treatment with itraconazole.
abstract: We report a case of seborrheic blepharitis treated with oral itraconazole during a short period. Direct examination using Parker KOH revealed numerous hyphae and spores of Malassezia in the scale. Low-dose itraconazole pulse therapy (200 mg daily, 7 days a month) was quite effective. This is the second case in which we also observed a unique fungal conformation which looked like tinea versicolor. The evidence strongly suggests that Malassezia is one of the major causative agents of seborrheic blepharitis.
authors.affiliation: Department of Dermatology, Showa University Fujigaoka Hospital, Yokohama, Japan.
authors.forename: Junya
authors.initials: J
authors.lastname: Ninomiya
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Nakabayashi
authors.forename: Ryota
authors.initials: R
authors.lastname: Higuchi
authors.forename: Iwao
authors.initials: I
authors.lastname: Takiuchi
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage*; D001762:Blepharitis / Q000188:drug therapy*; D012628:Dermatitis, Seborrheic / Q000188:drug therapy*; D003881:Dermatomycoses / Q000188:drug therapy*; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage*; D008290:Malassezia; D008297:Male; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole