title: [Biological exploration of food allergy].
abstract: Most of the time, food allergies are the consequence of an immediate IgE mediated hypersensitivity. In France, the frequency of food allergies is of 3.24%, it raises 8% in children. Their number as been multiplied by 2 in 5 years. The biological approach of food allergy is based essentially on the detection and the measurement of specific IgE. To date, a high number of tests are marketed and it is important to determine which of them are of high quality, using analytical or clinical-biological evaluations. Some other ways are available to study thoroughly and to characterize the allergens responsible of clinical reactions: the detection of hidden allergens, the study of crossed reaction between food or between food and pollen, the modification of the allergens by food processing.
authors.affiliation: Laboratoire de biochimie médicale et pédiatrique, Faculté de médecine de Nancy, 9, avenue de la Forêt-de-Haye, BP-184, 54500 Vandoeuvre-lès-Nancy.
authors.forename: S
authors.initials: S
authors.lastname: Frémont
mesh_terms: D000328:Adult; D000367:Age Factors; D000485:Allergens / Q000276:immunology; D002648:Child; D003429:Cross Reactions; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000276:immunology; D005602:France / Q000453:epidemiology; D006632:Histamine / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D010938:Plant Oils / Q000009:adverse effects; D011058:Pollen / Q000276:immunology; D011852:Radioallergosorbent Test
chemical_list: D000485:Allergens; D010938:Plant Oils; D007073:Immunoglobulin E; D006632:Histamine