Physical exercise and mitochondrial function in human skeletal muscle.
Muscle adaptation to endurance training involves qualitative changes in intrinsic properties of mitochondria. After training, the ADP sensitivity of miitochondrion is decreased whereas the effect of creatine on respiration is increased. This results in an improved control of aerobic energy production. Acute exercise does not adversely affect mitochondrial function.
Tonkonogi
Michail
M
Department of Physiology and Pharmacology, Karolinska Instituet, Stockholm, Sweden. Michail.Tonkonogi@fyfa.ki.se
Sahlin
Kent
K
D000244:Adenosine Diphosphate / Q000378:metabolism; D002474:Cell-Free System; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008931:Mitochondria, Muscle / Q000378:metabolism / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D010725:Phosphocreatine / Q000378:metabolism; D014481:United States
D010725:Phosphocreatine; D000244:Adenosine Diphosphate