Applications of selective neutrality tests to molecular ecology.
This paper reviews how statistical tests of neutrality have been used to address questions in molecular ecology are reviewed. The work consists of four major parts: a brief review of the current status of the neutral theory; a review of several particularly interesting examples of how statistical tests of neutrality have led to insight into ecological problems; a brief discussion of the pitfalls of assuming a strictly neutral model if it is false; and a discussion of some of the opportunities and problems that molecular ecologists face when using neutrality tests to study natural selection.
Ford
Michael J
MJ
Northwest Fisheries Science Center, Conservation Biology Division, 2725 Montlake Blvd E, Seattle, WA 98112, USA. mike.ford@noaa.gov
D000818:Animals; D004463:Ecology; D019143:Evolution, Molecular; D006801:Humans; D008958:Models, Molecular; D008967:Molecular Biology; D017434:Protein Structure, Tertiary; D012641:Selection, Genetic