Isolation from a healthy carrier and characterization of a Neisseria meningitidis strain that is deficient in gamma-Glutamyl aminopeptidase activity.
gamma-Glutamyl aminopeptidase (GGT) activity is used as a specific marker for the identification of Neisseria meningitidis. We isolated from a healthy carrier and characterized an N. meningitidis isolate which lacked the activity due to the insertional mutation of the ggt gene, suggesting that naturally occurring N. meningitidis isolates do not always possess GGT activity.
Takahashi
Hideyuki
H
Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Japan.
Tanaka
Hiroshi
H
Inouye
Hiroo
H
Kuroki
Toshiro
T
Watanabe
Yuko
Y
Yamai
Shiro
S
Watanabe
Haruo
H
D000328:Adult; D000595:Amino Acid Sequence; D001483:Base Sequence; D002353:Carrier State / Q000382:microbiology*; D004251:DNA Transposable Elements / Q000235:genetics; D004269:DNA, Bacterial / Q000032:analysis; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000382:microbiology*; D008969:Molecular Sequence Data; D009154:Mutation; D009345:Neisseria meningitidis / Q000201:enzymology* / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D005723:gamma-Glutamyltransferase / Q000172:deficiency* / Q000235:genetics / Q000378:metabolism
D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D005723:gamma-Glutamyltransferase