Allotypic variation of the third component of complement in an aboriginal tribe in Taiwan.
In 1981, we reported a case of complete absence of C3 in an aborigine (Atayal tribe) girl in Taiwan. Since then, serum C3 level and allotypes have been evaluated in 1,372 Atayal people. The incidence of C3 deficient heterozygote was 15.7%. All the C3 allotype was C3S. The gene frequency was 1. The Atyayal population seems more akin to Mongol populations than to Caucasians.
Lin
Ching-Yuang
CY
Department of Pediatrics, Taipei Veterans General Hospital, Taiwan. cylin2@vghtpe.gov.tw
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003176:Complement C3 / Q000172:deficiency* / Q000235:genetics*; D005260:Female; D006579:Heterozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D044469:Racial Groups; D013624:Taiwan / Q000208:ethnology
D003176:Complement C3