Beta-depsipeptides--the effect of a missing and a weakened hydrogen bond on the stability of the beta-peptidic 3(14)-helix.
The importance of hydrogen bonding in beta-peptide 3(14)-helices is demonstrated by an NMR analysis of three beta-heptadepsipeptides containing a 3-hydroxybutanoic residue in position 2, 4 or 6.
Seebach
Dieter
D
Laboratorium für Organische Chemie der Eidgenössischen Technischen Hochschule, ETH-Hönggerberg, Wolfgang-Pauli-Strasse 10, CH-8093 Zürich, Switzerland. seebach@org.chem.ethz.ch
Mahajan
Yogesh R
YR
Senthilkumar
Ramanathan
R
Rueping
Magnus
M
Jaun
Bernhard
B
D002942:Circular Dichroism; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry; D011487:Protein Conformation
D009842:Oligopeptides; D010100:Oxygen