title: Source-monitoring deficits for self-generated stimuli in schizophrenia: multinomial modeling of data from three sources.
abstract: BACKGROUND
  Schizophrenia patients, particularly those with specific types of hallucinations and delusions, may have a deficit in monitoring the generation of thought. This deficit, termed autonoetic agnosia, may result in the conclusion that self-generated thoughts come from an external source.
  
  
  METHODS
  This study assessed autonoetic agnosia in 29 schizophrenic patients and 19 controls by applying a recently developed technique from cognitive science: multinomial modeling of source-monitoring data.
  
  
  RESULTS
  Schizophrenic patients demonstrated deficits in monitoring the source of self-generated information, yet performed similarly to controls in monitoring the source of visual and auditory information. Schizophrenic patients with specific "target" symptoms such as auditory hallucinations and thought insertion had greater deficits than other patients in recognizing self-generated information.
  
  
  CONCLUSIONS
  This study offers partial support for the notion that schizophrenic patients manifest autonoetic agnosia.
authors.affiliation: Department of Psychiatry and Behavioural Science, Duke University Medical Center, P.O. Box 3270, Durham, NC 27710, USA. richard.keefe@duke.edu
authors.forename: Richard S E
authors.initials: RS
authors.lastname: Keefe
authors.forename: Miriam C
authors.initials: MC
authors.lastname: Arnold
authors.forename: Ute J
authors.initials: UJ
authors.lastname: Bayen
authors.forename: Joseph P
authors.initials: JP
authors.lastname: McEvoy
authors.forename: William H
authors.initials: WH
authors.lastname: Wilson
mesh_terms: D000328:Adult; D000377:Agnosia / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology*; D005260:Female; D006212:Hallucinations / Q000150:complications / Q000175:diagnosis; D006801:Humans; D008297:Male; D021641:Recognition, Psychology; D012559:Schizophrenia / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D012653:Self Stimulation; D013850:Thinking; D014888:Wechsler Scales