[Initial antibiotic therapy in maternal-fetal infections which include ampicillin even in countries where listeriosis is an incidental disease].
Neonatal listeriosis is an exceptional disease in Northern Africa. Hence, protocols for maternal-fetal infection treatment include only a third generation cephalosporin and an aminoside. This protocol does not take into account the possibility of Listeria monocytogenes infection. We report a fatal case of neonatal listeriosis in Tunisia. The use of first antibiotics in maternal-foetal infection must be reconsidered when lacking sufficient bacteriological data and include systematically ampicillin in presumptive antibiotic protocols.
Boukadida
J
J
Laboratoire de microbiologie, Hôpital F. Hached, 4000 Sousse, Tunisie. jboukadida@lycos.com
Taher
N Bel Hadj
NB
Seket
B
B
Monastiri
K
K
Salem
N
N
Snoussi
N
N
D000328:Adult; D000583:Amikacin / Q000627:therapeutic use; D000667:Ampicillin / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002439:Cefotaxime / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D002985:Clinical Protocols; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000188:drug therapy*; D008088:Listeriosis / Q000151:congenital* / Q000188:drug therapy; D008297:Male; D010406:Penicillins / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D010406:Penicillins; D000667:Ampicillin; D000583:Amikacin; D002439:Cefotaxime