Retinal oxygen saturation levels in patients with central retinal vein occlusion.
OBJECTIVE
To validate the efficacy of Fourier transform-based spectral retinal imaging (SRI) in quantifying retinal ischemia.


METHODS
Prospective, observational case series.


METHODS
Eleven eyes of 10 patients with central retinal vein occlusion (CRVO) and 4 fellow unaffected eyes of selected patients were examined by both fluorescein angiography and SRI. The fluorescein angiograms were correlated with oxygen saturation maps that were calculated from the SRI.


RESULTS
Oxygen saturation levels in the fundus were shown as color grading in 35 degrees fundus images processed by SRI. This grading correlated well with the severity of CRVO, as estimated by fluorescein angiography.


CONCLUSIONS
The severity of circulatory disturbances in CRVO may be graded by applying SRI.
Yoneya
Shin
S
Department of Ophthalmology, Saitama Medical School, Moroyama, Saitama, Japan.
Saito
Tamiya
T
Nishiyama
Yoko
Y
Deguchi
Tatsuya
T
Takasu
Masayuki
M
Gil
Tamir
T
Horn
Eli
E
D001783:Blood Flow Velocity; D005451:Fluorescein Angiography; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007368:Interferometry; D007511:Ischemia / Q000175:diagnosis / Q000503:physiopathology*; D008027:Light; D010100:Oxygen / Q000097:blood*; D011446:Prospective Studies; D012039:Regional Blood Flow; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000503:physiopathology*; D012171:Retinal Vessels / Q000503:physiopathology*
D010100:Oxygen