title: Cardiac arrhythmias in aluminium phosphide poisoning studied by on continuous holter and cardioscopic monitoring.
abstract: Variable incidences of cardiac arrhythmias (based on isolated 12 lead ECG records) have been reported in patients of aluminium phosphide (ALP) poisoning. We did continuous holter and cardioscopic monitoring in ICU in 30 patients of acute ALP poisoning. Supraventricular and ventricular ectopics were recorded in each and every patient. Life threatening ventricular tachycardia was recorded in 40% cases and ventricular fibrillation in 23.3% cases. Supraventricular tachycardia and atrial flutter/fibrillation occurred in 46.7% and 20% patients, respectively. ST-T changes simulating myocardial ischaemia were also present in all patients (S-T depression in 90%, S-T elevation in 10%). One-third of the patients developed variable degrees of heart block, IV amiodarone/xylocard could revert dangerous ventricular arrhythmias to sinus rhythm in 4 cases. Toxic myocarditis produced by phosphine seems to be responsible for the development of these arrhythmias.
authors.affiliation: Department of Medicine, Pt. BDS PGIMS, Rohtak, Haryana, India.
authors.forename: S B
authors.initials: SB
authors.lastname: Siwach
authors.forename: H
authors.initials: H
authors.lastname: Singh
authors.lastname: Jagdish
authors.forename: V K
authors.initials: VK
authors.lastname: Katyal
authors.forename: G
authors.initials: G
authors.lastname: Bhardwaj
mesh_terms: D000293:Adolescent; D000328:Adult; D017607:Aluminum Compounds / Q000506:poisoning*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000175:diagnosis; D015716:Electrocardiography, Ambulatory; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D010575:Pesticides / Q000506:poisoning*; D010720:Phosphines / Q000506:poisoning*; D013406:Suicide, Attempted
chemical_list: D017607:Aluminum Compounds; D010575:Pesticides; D010720:Phosphines; C001864:aluminum phosphide