Thiopurine S-methyltransferase: a genetic polymorphism that affects a small number of drugs in a big way.
Evans
William E
WE
St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA. william.evans@stjude.org
D001379:Azathioprine / Q000009:adverse effects*; D003093:Colitis, Ulcerative / Q000188:drug therapy / Q000201:enzymology*; D003424:Crohn Disease / Q000188:drug therapy / Q000201:enzymology*; D005838:Genotype; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008780:Methyltransferases / Q000235:genetics* / Q000378:metabolism; D009503:Neutropenia / Q000139:chemically induced; D010641:Phenotype; D011110:Polymorphism, Genetic
D007166:Immunosuppressive Agents; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D001379:Azathioprine