Synthesis of milbemycins beta9 and beta10 from milbemycins A3 and A4 and their biological activities.
Chemical derivation methods were used to prepare milbemycins beta9 and beta10 from milbemycins A3 and A4. Their acaricidal activities were also assessed against the organophosphorus-sensitive two-spotted spider mite (Tetranychus urticae) on primary leaves of cowpea plants (Vigna sinesis Savi species) by spraying.
Tsukiyama
Takahiro
T
Agroscience Research Laboratories, Sankyo Co. Ltd., Shiga, Japan. tukiya@yasu.sankyo.co.jp
Kinoshita
Ayako
A
Ichinose
Reiji
R
Sato
Kazuo
K
D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D007887:Fabaceae / Q000469:parasitology; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018515:Plant Leaves / Q000469:parasitology; D040102:Tetranychidae / Q000187:drug effects
D000900:Anti-Bacterial Agents; D018942:Macrolides; C471414:milbemycin beta10; C471413:milbemycin beta9; C027837:moxidectin