New oxidative demetalation protocol for molybdenum pi-complexes: enantiocontrolled synthesis of unsaturated ketones and lactones.
An efficient and general oxidative demetalation of (eta(3)-allyl)molybdenum complexes using pyridinium dichromate allows the introduction of a carbonyl group at an allylic terminus of the pi-system. The process takes place with high regiocontrol and can lead to the preparation of unsaturated ketones and lactones of high enantiopurity.
Alcudia
Ana
A
Department of Chemistry, Emory University, 1515 Pierce Drive, Atlanta, Georgia 30322, USA.
Arrayás
Ramón Gómez
RG
Liebeskind
Lanny S
LS
D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D008982:Molybdenum; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D007659:Ketones; D007783:Lactones; D008982:Molybdenum