title: Germination inhibitory constituents from Erigeron annuus.
abstract: (5-Butyl-3-oxo-2,3-dihydrofuran-2-yl)-acetic acid was isolated from the flowers of Erigeron annuus as one of four germination inhibitory constituents. Its structure was determined by analysis of MS and NMR spectroscopic data. Three known compounds, 3-hydroxy-pyran-4-one, 4-hydroxycinnamic acid, and 3,4-dihydroxycinnamic acid methyl ester were also identified as active constituents. These compounds showed 50% inhibitory effects (IC(50)) on the germination of lettuce seed at concentrations of 2.13+/-0.03, 12.85+/-0.56, 4.97+/-0.24, and 4.87+/-0.25 mM, respectively. 4-Hydroxybenzoic acid was used as a positive control, displaying an IC(50) value of 4.02+/-0.39 mM.
authors.affiliation: Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, 570-749, Chonbuk, Republic of Korea.
authors.forename: Hyuncheol
authors.initials: H
authors.lastname: Oh
authors.forename: Sunyoung
authors.initials: S
authors.lastname: Lee
authors.forename: Ho-Sub
authors.initials: HS
authors.lastname: Lee
authors.forename: Dong-Heon
authors.initials: DH
authors.lastname: Lee
authors.forename: Seung Yeob
authors.initials: SY
authors.lastname: Lee
authors.forename: Hun-Taeg
authors.initials: HT
authors.lastname: Chung
authors.forename: Tae Soo
authors.initials: TS
authors.lastname: Kim
authors.forename: Tae-Oh
authors.initials: TO
authors.lastname: Kwon
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D018525:Germination / Q000187:drug effects*; D020128:Inhibitory Concentration 50; D018545:Lactuca / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010936:Plant Extracts / Q000494:pharmacology*; D012639:Seeds / Q000187:drug effects
chemical_list: D010936:Plant Extracts