title: Isolation from a healthy carrier and characterization of a Neisseria meningitidis strain that is deficient in gamma-Glutamyl aminopeptidase activity.
abstract: gamma-Glutamyl aminopeptidase (GGT) activity is used as a specific marker for the identification of Neisseria meningitidis. We isolated from a healthy carrier and characterized an N. meningitidis isolate which lacked the activity due to the insertional mutation of the ggt gene, suggesting that naturally occurring N. meningitidis isolates do not always possess GGT activity.
authors.affiliation: Department of Bacteriology, National Institute of Infectious Diseases, Tokyo, Japan.
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Takahashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tanaka
authors.forename: Hiroo
authors.initials: H
authors.lastname: Inouye
authors.forename: Toshiro
authors.initials: T
authors.lastname: Kuroki
authors.forename: Yuko
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Shiro
authors.initials: S
authors.lastname: Yamai
authors.forename: Haruo
authors.initials: H
authors.lastname: Watanabe
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D001483:Base Sequence; D002353:Carrier State / Q000382:microbiology*; D004251:DNA Transposable Elements / Q000235:genetics; D004269:DNA, Bacterial / Q000032:analysis; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000382:microbiology*; D008969:Molecular Sequence Data; D009154:Mutation; D009345:Neisseria meningitidis / Q000201:enzymology* / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D005723:gamma-Glutamyltransferase / Q000172:deficiency* / Q000235:genetics / Q000378:metabolism
chemical_list: D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D005723:gamma-Glutamyltransferase