title: Carcinoma larynx--topographical distribution.
abstract: One hundred and sixty subjects were included in our study, collected from four hospitals in Dhaka City. The mean age (+/- SD) of study subjects were 54.67 +/- 11.27 years. Out of 160 subjects 155 was males and 5 were females, and male to female ratio was 31:1. The highest number of study subjects was related to cultivation (40.62%). The majority of study subjects were from the low socio-economic status (68.72%). Carcinoma larynx is a multifactorial disease. Smoking and chewing habit are the most important factors associated with carcinoma larynx. Most of the male (93.12%) subjects were smoker. One hundred and fifteen (71.87%) subjects were found chewing habit of betel leaves with other ingredients. Hoarseness of voice was the commonest symptom 65.62%. Regional distribution of tumour showed supraglottic carcinoma topping the list (69.38%) followed by glottic carcinoma (30.62%) and there was no subglottic carcinoma. Site involvement in supraglottic carcinoma was found in combined location topping the list (89.20%). In glottic carcinoma majority was found glottic with supraglottic extension (65.31%). In majority cases growth were exophytic 52.50%. Palpable lymph mode was found in 48.75% of cases. All the carcinoma of larynx was found histologically of squamous cell type.
authors.affiliation: Faculty of Postgraduate Medicine, University of Dhaka.
authors.forename: M Rojibul
authors.initials: MR
authors.lastname: Haque
authors.forename: Mohammad
authors.initials: M
authors.lastname: Abdullah
authors.forename: M
authors.initials: M
authors.lastname: Alauddin
authors.forename: Abdullah
authors.initials: A
authors.lastname: al-Haroon
authors.forename: M A
authors.initials: MA
authors.lastname: Majed
authors.forename: M Suhrab
authors.initials: MS
authors.lastname: Ali
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001114:Areca / Q000009:adverse effects; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology*; D000431:Ethanol / Q000009:adverse effects; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D017678:Sex Distribution; D014026:Nicotiana / Q000009:adverse effects
chemical_list: D000431:Ethanol