Structure revision of medermycin/lactoquinomycin a and of related C-8 glycosylated naphthoquinones.
[reaction: see text] On the basis of chemical and spectral data, the structure of the medermycin/lactoquinomycin A has been revised, which has also led to the revision of related C-glycosylated naphthoquinone antibiotics such as lactoquinomycin B, menoxymycins A and B, G15-F, and G15-G.
Léo
Pierre-Marc
PM
LEDSS, UMR-CNRS No. 5616, Département de Chimie, Université Joseph Fourier-Grenoble 1, 38402 Saint Martin d'Hères, France.
Morin
Christophe
C
Philouze
Christian
C
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D006031:Glycosylation; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009285:Naphthoquinones / Q000737:chemistry*; D000095622:Benzoisochromanequinones
D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; C047326:lactoquinomycin A; C013104:medermycin; D000095622:Benzoisochromanequinones