title: Risk factors for oral soft tissue lesions in an adult Spanish population.
abstract: OBJECTIVE
  The aims of this study were (i) to determine the prevalence of oral lesions in adults over 30 years old in the city of Oviedo (Spain), and (ii) to analyze the relationship between the prevalence of oral lesions, toxic habits (tobacco and alcohol) and denture wearers in these patients.
  
  
  METHODS
  A representative sample of the adult population in Oviedo (Spain) was obtained through randomized sampling (n = 753); a total of 308 (41%) subjects were finally included in the study. The observed oral pathology was classified according to the WHO criteria and earlier epidemiological studies.
  
  
  RESULTS
  A little over half of all patients (51.1%) had oral lesions. The most frequent lesions were frictional lesion (7.5%), traumatic ulcer (7.1%), denture stomatitis and pseudomembranous candidosis (6.5%), followed by melanin pigmentation (5.8%) and denture-induced hyperplasia (5.2%), plicated tongue (3.9%), lichen planus and hemangioma (3.2%), angular cheilitis and cheek biting (2.9%), fibrous hyperplasia and coated tongue (2.6%), recurrent aphthae (1.9%) and oral leukoplakia (1.6%). In relation to leukoplakia, the odds ratio (OR) of heavy drinkers was 15.98 and the OR of heavy smokers was 12.37. The OR of heavy smokers or heavy drinkers diagnosed of frictional lesion was four times greater than that of nonsmokers or nondrinkers. The OR of heavy smokers with melanic pigmentations was 4.08. The OR of complete denture wearers with candidosis was 11.38. The OR of partial removable denture wearers with hemangioma was 5.01.
  
  
  CONCLUSIONS
  This study shows the relation of heavy tobacco and heavy alcohol to traumatic keratosis and leukoplakia, and of complete dentures to pseudomembranous candidosis, fibrous hyperplasia and stomatitis. Programs designed to eradicate toxic factors (alcohol and tobacco) should, therefore, be implemented with adequate maintenance of dentures.
authors.affiliation: Department of Oral Pathology, Dental School, University of Oviedo, Spain, Department of Public Health, Regional Institute of Health, Oviedo, Spain, Department of Oral and Maxillofacial Surgery, Dental School, University of Oviedo, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: García-Pola Vallejo
authors.forename: A I
authors.initials: AI
authors.lastname: Martínez Díaz-Canel
authors.forename: J M
authors.initials: JM
authors.lastname: García Martín
authors.forename: M
authors.initials: M
authors.lastname: González García
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000453:epidemiology; D000704:Analysis of Variance; D003778:Dentures / Q000009:adverse effects / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000453:epidemiology* / Q000209:etiology*; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D012494:Sampling Studies; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology; D013030:Spain / Q000453:epidemiology