Delayed striate cortical activation during spatial attention.
Recordings of event-related potentials (ERPs) and event-related magnetic fields (ERMFs) were combined with functional magnetic resonance imaging (fMRI) to study visual cortical activity in humans during spatial attention. While subjects attended selectively to stimulus arrays in one visual field, fMRI revealed stimulus-related activations in the contralateral primary visual cortex and in multiple extrastriate areas. ERP and ERMF recordings showed that attention did not affect the initial evoked response at 60-90 ms poststimulus that was localized to primary cortex, but a similarly localized late response at 140-250 ms was enhanced to attended stimuli. These findings provide evidence that the primary visual cortex participates in the selective processing of attended stimuli by means of delayed feedback from higher visual-cortical areas.
Noesselt
Toemme
T
Department of Neurology II, 39120 Magdeburg, Germany. toemme@neuro2.med.uni-magdeburg.de
Hillyard
Steve A
SA
Woldorff
Marty G
MG
Schoenfeld
Ariel
A
Hagner
Tilman
T
Jäncke
Lutz
L
Tempelmann
Claus
C
Hinrichs
Hermann
H
Heinze
Hans-Jochen
HJ
D000328:Adult; D001288:Attention / Q000502:physiology*; D001931:Brain Mapping; D002560:Cerebrovascular Circulation / Q000502:physiology; D003463:Cues; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005246:Feedback / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D009415:Nerve Net / Q000502:physiology; D009433:Neural Inhibition / Q000502:physiology; D009483:Neuropsychological Tests; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology*; D013028:Space Perception / Q000502:physiology*; D014793:Visual Cortex / Q000033:anatomy & histology / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology*; D014795:Visual Pathways / Q000033:anatomy & histology / Q000502:physiology*