[Diabetic cardiomyopathy: concept, heart function, and pathogenesis].
The diabetic cardiomyopathy is a disease caused by diabetes and is characterised by the presence of diastolic and/or systolic left ventricular dysfunction. Diabetes may produce metabolic alterations, interstitial fibrosis, myocellular hypertrophy, microvascular disease and autonomic dysfunction. It is thought that all of them may cause cardiomyopathy. Other abnormalities that are usually associated with diabetes such as hypertension, coronary artery disease and nephropathy should be excluded before diagnosing diabetic cardiomyopathy. There is no evidence that diabetic cardiomyopathy alone can produce heart failure. However, subclinical ventricular dysfunction has been described in young asymptomatic diabetic patients without other diseases that could affect the cardiac muscle. In these cases we should consider that diabetes is the only cause of the myocardial disease. More studies are needed to know the natural history of diabetic cardiomyopathy.
Codinach Huix
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P
Servicio de Cardiología, Hospital de la Creu Roja, C/Dos de Maig, 301, 08025 Barcelona.
Freixa Pamias
R
R
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D001342:Autonomic Nervous System Diseases / Q000150:complications / Q000503:physiopathology; D009202:Cardiomyopathies / Q000175:diagnosis / Q000209:etiology*; D003327:Coronary Disease / Q000150:complications; D048909:Diabetes Complications; D003925:Diabetic Angiopathies / Q000150:complications; D003928:Diabetic Nephropathies / Q000150:complications; D003929:Diabetic Neuropathies / Q000150:complications / Q000503:physiopathology; D003971:Diastole; D004734:Energy Metabolism; D005355:Fibrosis; D006801:Humans; D006973:Hypertension / Q000150:complications; D006984:Hypertrophy; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology
D000319:Adrenergic beta-Antagonists