The interaction of medications used in palliative care.
Palliative care uses several classes of drugs, which are handled by the CYP P450 system. Interaction of drugs in this setting requires ongoing vigilance by the physician. Phenocopying may be more common than previously realized.
Bernard
Stephen A
SA
Division of Hematology and Medical Oncology, University of North Carolina, School of Medicine, 3009 Old Clinic Building, CB #7305, Chapel Hill, NC 27599-7305, USA. bernmed@med.unc.edu
D000700:Analgesics / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000928:Antidepressive Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D004347:Drug Interactions / Q000235:genetics / Q000502:physiology; D004359:Drug Therapy, Combination; D006801:Humans; D008657:Metabolic Clearance Rate; D009251:NADPH-Ferrihemoprotein Reductase / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D009369:Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D010166:Palliative Care / Q000379:methods*; D011110:Polymorphism, Genetic / Q000235:genetics; D011619:Psychotropic Drugs / Q000009:adverse effects
D000700:Analgesics; D000900:Anti-Bacterial Agents; D000928:Antidepressive Agents; D000970:Antineoplastic Agents; D011619:Psychotropic Drugs; D009251:NADPH-Ferrihemoprotein Reductase