title: Rapamycin blocks the generation of regulatory T cells facilitated by posttransplant infusion of donor T cells through increasing the apoptosis of thymic CD4(+)CD25(+) cells.
authors.affiliation: Centre for the Study of Liver Disease, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam Road 102, Hong Kong, China.
authors.forename: Tung-Yu
authors.initials: TY
authors.lastname: Tsui
authors.forename: C-K
authors.initials: CK
authors.lastname: Lau
authors.forename: H J
authors.initials: HJ
authors.lastname: Schlitt
authors.forename: S-T
authors.initials: ST
authors.lastname: Fan
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D015704:CD4 Antigens / Q000276:immunology*; D007165:Immunosuppression Therapy / Q000379:methods; D017710:Lymphocyte Transfusion; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D015375:Receptors, Interleukin-2 / Q000276:immunology*; D020123:Sirolimus / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000145:classification / Q000187:drug effects / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology
chemical_list: D015704:CD4 Antigens; D015375:Receptors, Interleukin-2; D020123:Sirolimus