DNA hybridization test: rapid diagnostic tool for excluding bacterial vaginosis in pregnant women with symptoms suggestive of infection.
This prospective comparative study evaluated a DNA hybridization test (Affirm VPIII) as an alternative to Gram stain for the diagnosis of bacterial vaginosis. We examined vaginal smears from 1,725 pregnant women between the 12th and 36th weeks of gestation with clinical signs of vaginal infection. The DNA hybridization test compared well with Gram stain and can be used as a rapid diagnostic tool to exclude bacterial vaginosis.
Witt
Armin
A
Department of Obstetrics and Gynecology, University of Vienna Medical School, Austria.
Petricevic
Ljubomir
L
Kaufmann
Ulrike
U
Gregor
Hubertus
H
Kiss
Herbert
H
D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D006194:Gardnerella vaginalis / Q000302:isolation & purification; D006801:Humans; D009693:Nucleic Acid Hybridization / Q000379:methods*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000382:microbiology; D011446:Prospective Studies; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013997:Time Factors; D014621:Vagina / Q000382:microbiology; D014626:Vaginal Smears; D016585:Vaginosis, Bacterial / Q000175:diagnosis* / Q000382:microbiology
D004269:DNA, Bacterial; D011933:Reagent Kits, Diagnostic