Invasive pulmonary filamentous fungal infection in a patient receiving inhaled corticosteroid therapy.
We report a case of invasive pulmonary filamentous fungal infection in a patient with chronic obstructive pulmonary disease who was treated with a conventional dose of inhaled fluticasone in the absence of other causes of immunosuppression. This case demonstrates the potential risk for opportunistic fungal infections in patients treated with high-potency lipophilic inhaled corticosteroids.
Peter
Elvis
E
Department of Medicine, School of Medicine and Biochemical Sciences, State University of New York, Buffalo, NY, USA.
Bakri
Faris
F
Ball
Donna M
DM
Cheney
Richard T
RT
Segal
Brahm H
BH
D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D001232:Aspergillus fumigatus; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D008172:Lung Diseases, Fungal / Q000209:etiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
D000305:Adrenal Cortex Hormones