title: Fibrosing mediastinitis secondary to zygomycosis in a twenty-two-month-old child.
abstract: We report the case of a 22-month-old immunocompetent male child with fibrosing mediastinitis secondary to zygomycosis, an unusual presentation of a rare fungal infection. This patient was successfully treated with amphotericin B and itraconazole for 20 weeks. Stenting of the superior vena cava was helpful in relieving the patient's superior vena cava syndrome.
authors.affiliation: Department of Pediatrics, San Antonio Military Pediatric Center, Lackland Air Force Base, TX 78236-5300, USA. brian.robertson@lackland.af.mil
authors.forename: Brian D
authors.initials: BD
authors.lastname: Robertson
authors.forename: Matt A
authors.initials: MA
authors.lastname: Bautista
authors.forename: Tod S
authors.initials: TS
authors.lastname: Russell
authors.forename: Anne L
authors.initials: AL
authors.lastname: Naclerio
authors.forename: Mary E
authors.initials: ME
authors.lastname: Porisch
authors.forename: Donald L
authors.initials: DL
authors.lastname: Sorrells
authors.forename: Richard T
authors.initials: RT
authors.lastname: Fiser
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D005355:Fibrosis; D006801:Humans; D007223:Infant; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D008480:Mediastinitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D015607:Stents; D013479:Superior Vena Cava Syndrome / Q000188:drug therapy / Q000601:surgery; D016896:Treatment Outcome; D020096:Zygomycosis / Q000150:complications* / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B