title: Successful lung volume reduction surgery in a child with severe airflow obstruction and hyperinflation due to constrictive bronchiolitis.
abstract: Lung volume reduction surgery (LVRS) may improve pulmonary function in patients with severe emphysema. However, its effects in other types of obstructive lung disease are unknown. To delay the need for lung transplantation, we performed LVRS in a 14-year-old boy with disabling airflow obstruction/hyperinflation secondary to postinfectious bronchiolitis nonresponsive to medical therapy. Within days after LVRS, a major improvement of symptoms and lung function occurred and persisted for > 1 year. Our observation suggests that LVRS may be a novel treatment option in selected patients with extreme hyperinflation even if the underlying disease is not emphysema.
authors.affiliation: Pulmonary Division, University Hospital of Zürich, Switzerland. pneubloc@usz.unizh.ch
authors.forename: Konrad E
authors.initials: KE
authors.lastname: Bloch
authors.forename: Walter
authors.initials: W
authors.lastname: Weder
authors.forename: Annette
authors.initials: A
authors.lastname: Boehler
authors.forename: Marco P
authors.initials: MP
authors.lastname: Zalunardo
authors.forename: Erich W
authors.initials: EW
authors.lastname: Russi
mesh_terms: D000293:Adolescent; D001988:Bronchiolitis / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D010991:Plethysmography; D011013:Pneumonectomy; D012129:Respiratory Function Tests