title: [Personal and histopathological factors as prognostic variables in upper urothelial tumors undergoing surgery].
abstract: OBJECTIVE
  To analyze the influence of personal and histopathological factors as prognostic variables in the evolution of upper urothelial tumors submitted to radical surgery.
  
  
  METHODS
  Multifactorial retrospective study of a series of 61 patients submitted to radical surgery for upper urinary tract transitional cell tumors. Patient habits and histopathological factors are analyzed. The statistical significance of the different factors was analyzed using the Pearson chi-square test for the qualitative variables, with analysis of the residuals and Kaplan-Meier survival curves and statistical validation with the Mantel Cox test. The level of significance was p < 0.05.
  
  
  RESULTS
  A statistically significant correlation was found for tumor-related death and pathological stage, positive lymphadenectomy and positive lymphadenopathy on the CT (p < 0.05). The presence or absence of a history of smoking was not available for all patients and was therefore not evaluable. The most frequent reason for consultation was hematuria (39%). Tumor growth was mostly of the papillary type (79%), localization was mostly in the renal pelvis (30%) and the most frequent procedure was nephroureterectomy without endoscopic detachment (60%).
  
  
  CONCLUSIONS
  The pathological stage and a positive lymphadenectomy or the presence of positive lymphadenopathies on the CT were found to be prognostic factors in urothelial tumors of the upper urinary tract.
authors.affiliation: Servicio de Urología, Hospital General Universitario de Murcia, Murcia, España.
authors.forename: Felipe
authors.initials: F
authors.lastname: García García
authors.forename: Luis Orcar
authors.initials: LO
authors.lastname: Fontana Compiano
authors.forename: Julián
authors.initials: J
authors.lastname: García Ligero
authors.forename: Isabel
authors.initials: I
authors.lastname: Arcas Martínez-Salas
authors.forename: Francisco
authors.initials: F
authors.lastname: Martínez
authors.forename: Mariano
authors.initials: M
authors.lastname: Tomás Ros
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Rico Galiano
authors.forename: Andrés
authors.initials: A
authors.lastname: Sempere Gutiérrez
authors.forename: Juan Pedro
authors.initials: JP
authors.lastname: Morga Egea
authors.forename: Manuel
authors.initials: M
authors.lastname: Canteras Jordana
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D015993:Life Tables; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009392:Nephrectomy; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012907:Smoking / Q000453:epidemiology; D016019:Survival Analysis; D016896:Treatment Outcome; D014516:Ureteral Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery