Dental considerations for the paediatric AIDS/HIV patient.
HIV infection and AIDS are spreading rapidly among the world's children, especially among African-American and Hispanic children in the USA, and those in developing countries. Although recent research has identified several ways of preventing perinatal transmission of HIV, most of these methods are too expensive for widespread use in developing countries, where the epidemic is most severe. Oral manifestations are early and common clinical indicators of HIV infection and progression in children, as in adults, although the specific manifestations differ between adults and children. Oropharyngeal candidiasis is the most common sign of HIV infection in children and is significantly associated with markers of HIV disease progression. Other common oral manifestations in children include herpes simplex, linear gingival erythema, parotid enlargement and recurrent aphthous ulceration. Further research is needed on the ways in which oral manifestations can be used as predictors of disease progression; on the impact of the limited availability of health care for impoverished families who are disproportionately affected by HIV infection; and on supportive care and its impact on infected children's quality of life.
Ramos-Gomez
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Department of Growth and Development, University of California San Francisco, and Pediatric Dental Services, San Francisco General Hospital, 94143-0753, USA. ramos@itsa.ucsf.edu
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology* / Q000517:prevention & control; D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D002177:Candidiasis / Q000453:epidemiology; D002180:Candidiasis, Oral / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries / Q000706:statistics & numerical data; D018450:Disease Progression; D004890:Erythema / Q000453:epidemiology; D005260:Female; D005882:Gingival Diseases / Q000453:epidemiology; D014943:Global Health; D015658:HIV Infections / Q000453:epidemiology* / Q000517:prevention & control; D006295:Health Resources; D006801:Humans; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D009059:Mouth Diseases / Q000453:epidemiology*; D010309:Parotitis / Q000453:epidemiology; D010608:Pharyngeal Diseases / Q000453:epidemiology; D011203:Poverty; D011788:Quality of Life; D013281:Stomatitis, Aphthous / Q000453:epidemiology; D013283:Stomatitis, Herpetic / Q000453:epidemiology; D014481:United States / Q000453:epidemiology
D015415:Biomarkers