title: Malignant struma ovarii: report of a case and review of the literature.
abstract: Malignant struma ovarii is a very rare disease and therefore there is neither common agreement on treatment regimens nor sufficient follow-up experience. The case of a 38-year-old woman with malignant struma ovarii is described. The patient presented with a clinically silent ovarian neoplasm discovered incidentally during investigations for metrorrhagia. The ovarian mass was resected and the tumor was found to be a teratoma. Within the teratoma a papillary thyroid carcinoma of the follicular variant was found. Subsequently, in order to make follow-up of the patient possible by thyroglobulin measurement and radioiodine whole body scintigraphy, near-total thyroidectomy was performed and the thyroid was found to be normal on histology. Whole body radioiodine scintigraphy with (131)I and ablation of the thyroid remnant by the administration of 80 mCi (131)I was performed. The patient recovered uneventfully and is now well.
authors.affiliation: Department of Endocrinology, Metaxa Hospital, Piraeus, Greece.
authors.forename: I
authors.initials: I
authors.lastname: Kostoglou-Athanassiou
authors.forename: I
authors.initials: I
authors.lastname: Lekka-Katsouli
authors.forename: L
authors.initials: L
authors.lastname: Gogou
authors.forename: L
authors.initials: L
authors.lastname: Papagrigoriou
authors.forename: I
authors.initials: I
authors.lastname: Chatonides
authors.forename: P
authors.initials: P
authors.lastname: Kaldrymides
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000473:pathology; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*; D013330:Struma Ovarii / Q000473:pathology*; D013724:Teratoma / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology