title: Viral etiology of acute respiratory infections among children in Porto Alegre, RS, Brazil.
abstract: Although acute respiratory infections (ARIs) are a major cause of child morbidity and mortality in Southern Brazil, little information is available on their seasonality and viral etiology. This study was conducted on children under 5 years of age with ARI to assess viral etiology in the State of Rio Grande do Sul, from 1990 to 1992. A total of 862 nasopharyngeal secretion (NPS) samples were tested using indirect immunofluorescence. The results showed that 316 (36.6%) NPS samples were positive: 26.2% for RSV, 6% for adenovirus, 1.7% for influenza viruses, 1.5% for parainfluenza viruses, and 1.2% for mixed infection. The mean viral prevalence rates in out-patient services, emergency wards, and in-patient hospital wards were 26.7%, 53% and 42.3%, respectively. Respiratory syncytial virus (RSV) and adenovirus accounted for 91.4 % of the viral diagnoses. RSV was more frequent in children under one year of age at the three levels of health care and was prevalent in infants under six months. Adenovirus was the most prevalent pathogen in hospitalized children, in 1992. Influenza A virus showed an increased prevalence with age among out-patient children. This study shows the annual occurrence of viral respiratory infections in the coldest months, with a significant annual variation in the frequency of RSV infection.
authors.affiliation: Seção de Virologia, Fundação Estadual de Produção e Pesquisa em Saúde, Porto Alegre, RS. smstra@bol.com.br
authors.forename: Selir M
authors.initials: SM
authors.lastname: Straliotto
authors.forename: Marilda M
authors.initials: MM
authors.lastname: Siqueira
authors.forename: Rafael L
authors.initials: RL
authors.lastname: Muller
authors.forename: Gilberto B
authors.initials: GB
authors.lastname: Fischer
authors.forename: Mara L T
authors.initials: ML
authors.lastname: Cunha
authors.forename: Sandra M
authors.initials: SM
authors.lastname: Nestor
mesh_terms: D000208:Acute Disease; D000258:Adenovirus Infections, Human / Q000150:complications* / Q000453:epidemiology; D001938:Brazil / Q000453:epidemiology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015995:Prevalence; D018357:Respiratory Syncytial Virus Infections / Q000150:complications* / Q000453:epidemiology; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000821:virology*