title: Beta-depsipeptides--the effect of a missing and a weakened hydrogen bond on the stability of the beta-peptidic 3(14)-helix.
abstract: The importance of hydrogen bonding in beta-peptide 3(14)-helices is demonstrated by an NMR analysis of three beta-heptadepsipeptides containing a 3-hydroxybutanoic residue in position 2, 4 or 6.
authors.affiliation: Laboratorium für Organische Chemie der Eidgenössischen Technischen Hochschule, ETH-Hönggerberg, Wolfgang-Pauli-Strasse 10, CH-8093 Zürich, Switzerland. seebach@org.chem.ethz.ch
authors.forename: Dieter
authors.initials: D
authors.lastname: Seebach
authors.forename: Yogesh R
authors.initials: YR
authors.lastname: Mahajan
authors.forename: Ramanathan
authors.initials: R
authors.lastname: Senthilkumar
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping
authors.forename: Bernhard
authors.initials: B
authors.lastname: Jaun
mesh_terms: D002942:Circular Dichroism; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry; D011487:Protein Conformation
chemical_list: D009842:Oligopeptides; D010100:Oxygen