[Fluorescence cystoscopy in bladder cancer: what future?].
Bladder transitional cell carcinoma, limited to the lamina propria, or superficial in 80% of the cases, is characterized by a high recurrence rate up to 70% in the three years following the first treatment. However, the constant evolution of the endoscopic techniques, useful to its diagnosis and treatment, contributed to reduce about by half this recurrence rate at three months. The actual development concerns new fluorescence detection methods, adapted to the standard endoscopic equipment. This new technique or fluorescence cystoscopy aims at improving the visual contrast between tumor and normal tissue in order to obtain a precise mapping of the diseased bladder. Thus, it allows to detect a carcinoma in situ (CIS) with a sensitivity around 80 to 90%. Its impact on the progression of the disease remains however to be demonstrated.
Jichlinski
P
P
Service d'urologie, centre hospitalier universitaire Vaudois, 1011 Lausanne, Suisse. Patrice.Jichlinski@chuv.hospvd.ch
Marti
A
A
Leisinger
H J
HJ
D000622:Aminolevulinic Acid; D002278:Carcinoma in Situ / Q000175:diagnosis*; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis*; D003558:Cystoscopy / Q000379:methods*; D003937:Diagnosis, Differential; D005453:Fluorescence; D006801:Humans; D012680:Sensitivity and Specificity; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*
D000622:Aminolevulinic Acid