title: Differential pulse adsorption voltammetry for determination of procaine hydrochloride at a pumice modified carbon paste electrode in pharmaceutical preparations and urine.
abstract: Procaine hydrochloride was determined by the differential pulse voltammetry (DPV) using a 6% (m/m) pumice modified carbon paste electrode in 1.25 x 10(-3) mol x l(-1) KH(2)PO(4) and Na(2)HPO(4) buffer solution (pH 6.88, 25 degrees C). The anodic peak potential used was +0.980 V (vs. SCE). A good linear relationship was realized between the anodic peak current and procaine concentration in the range of 9.0 x 10(-7)-2.6 x 10(-5) mol x l(-1) with the detection limit of 5.0 x 10(-8) mol x l(-1). The recovery was 95.2-104.8% with the relative standard deviation of 3.2% (n=10). The pharmaceutical preparations, procaine hydrochloride injection and the urine samples were determined with the desirable results.
authors.affiliation: Department of Chemistry and Chemical Engineering, Yangzhou University, 225002, Yangzhou, People's Republic of China.
authors.forename: Cheng Yin
authors.initials: CY
authors.lastname: Wang
authors.forename: Xiao Ya
authors.initials: XY
authors.lastname: Hu
authors.forename: Gen Di
authors.initials: GD
authors.lastname: Jin
authors.forename: Zong Zhou
authors.initials: ZZ
authors.lastname: Leng
mesh_terms: D000779:Anesthetics, Local / Q000032:analysis* / Q000652:urine; D002138:Calibration; D002244:Carbon; D004563:Electrochemistry; D004566:Electrodes; D006801:Humans; D007202:Indicators and Reagents; D011343:Procaine / Q000032:analysis* / Q000652:urine; D015203:Reproducibility of Results; D017640:Silicates / Q000737:chemistry*
chemical_list: D000779:Anesthetics, Local; D007202:Indicators and Reagents; D017640:Silicates; D011343:Procaine; D002244:Carbon; C005144:pumice