Cross-infection due to imipenem-resistant Bacteroides fragilis associated with a totally implantable venous port.
Four patients in an oncology ward developed Bacteroides fragilis bacteremia over a 12-day period. Cross-infection between two of them, due to an imipenem-resistant strain, was demonstrated by epidemiological investigation and genotypic typing methods (arbitrarily primed PCR fingerprinting and nucleotide sequencing of the cfiA genes and upstream IS1186/IS1168 elements).
Arpin
Corinne
C
Laboratoire de Microbiologie, Faculté de Pharmacie, Université de Bordeaux 2, France.
Dubois
Véronique
V
Rogues
Anne-Marie
AM
Menard
Fanny
F
Gavinet
Anne-Marie
AM
Maire
Jean-Pierre
JP
Gachie
Jean-Pierre
JP
Bezian
Marie-Christine
MC
Quentin
Claudine
C
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology; D001426:Bacterial Proteins; D015373:Bacterial Typing Techniques; D001442:Bacteroides Infections / Q000453:epidemiology / Q000382:microbiology; D001441:Bacteroides fragilis / Q000145:classification* / Q000187:drug effects* / Q000235:genetics; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis; D024881:Drug Resistance, Bacterial; D005260:Female; D005838:Genotype; D006801:Humans; D015378:Imipenem / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000150:complications; D017422:Sequence Analysis, DNA; D013845:Thienamycins / Q000494:pharmacology*; D001618:beta-Lactamases / Q000235:genetics
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D013845:Thienamycins; D015378:Imipenem; D001618:beta-Lactamases; C063912:carbapenemase