January 2002: 59-year-old woman with an intrasellar lesion.
An intrasellar lesion resembling a hormone-inactive pituitary adenoma was resected in a 59-year-old woman. The well-differentiated benign tumor was composed of ganglion-like cells, clusters of adenohypophyseal tissue as well as a GH-expressing adenoma. In addition, small cells exhibited an intermediate neuronal and epithelial immunoreactivity. Surrounding the tumor was a spindle cell component that histologically resembled Antoni A areas of a schwannoma, but showed a mixed immunohistochemical profile. Final diagnosis was intrasellar glioneuronal hamartoma with GH-cell pituitary adenoma.
Hans
Volkmar H J
VH
Institute for Neuropathology, University Hospital, Bonn, Germany.
Urbach
Horst
H
Kristof
Rudolph A
RA
Deckert
Martina
M
D000236:Adenoma / Q000473:pathology / Q000601:surgery; D005221:Fatigue / Q000209:etiology; D005260:Female; D005729:Ganglioneuroma / Q000473:pathology / Q000601:surgery; D006261:Headache / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis / Q000601:surgery; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*