title: The Ca/P range of nanoapatitic calcium phosphate cements.
abstract: Nanoapatites are apatites consisting of nanometer size crystals. The commercial calcium phosphate cements set by the precipitation of nanoapatitic calcium phosphates in the range 1.5 < or = Ca/P < 1.8. In this study it is shown that a continuum of nanoapatites can precipitate in the range 0.8 < Ca/P< or = 1.5. In order to be formed these nanoapatites need to incorporate K+ ions. In addition they can incorporate some Na+ ions. Upon immersion in aqueous solutions these nanoapatites loose phosphate, K+ and Na+ so that in an open system they are transformed into calcium deficient hydroxyapatite Ca9(HPO4)(PO4)5OH within about 2 months.
authors.affiliation: University of Nijmegen, Ohe en Laak, The Netherlands.
authors.forename: F C M
authors.initials: FC
authors.lastname: Driessens
authors.forename: M G
authors.initials: MG
authors.lastname: Boltong
authors.forename: E A P
authors.initials: EA
authors.lastname: de Maeyer
authors.forename: R
authors.initials: R
authors.lastname: Wenz
authors.forename: B
authors.initials: B
authors.lastname: Nies
authors.forename: J A
authors.initials: JA
authors.lastname: Planell
mesh_terms: D001672:Biocompatible Materials; D002118:Calcium / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D003738:Dental Cements / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D007477:Ions; D008274:Magnesium / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry*; D011188:Potassium / Q000378:metabolism; D017680:Potassium Compounds / Q000737:chemistry; D012964:Sodium / Q000378:metabolism; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D003738:Dental Cements; D007477:Ions; D010710:Phosphates; D017680:Potassium Compounds; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; D017886:Durapatite; C020243:calcium phosphate; D012964:Sodium; C013216:potassium phosphate; D008274:Magnesium; C485829:calcium phosphate, dibasic, anhydrous; D011188:Potassium; C018279:sodium phosphate; D002118:Calcium