Fatigue in cholestatic liver disease--a perplexing symptom.
Fatigue is an important symptom and a quality of life determinant in patients with cholestatic liver disease. The pathogenesis of fatigue is obscure, although alterations in central neurotransmission and peripheral muscle dysfunction have been incriminated. No effective treatment is available at present. The available literature on fatigue in cholestatic liver disease is reviewed.
Kumar
D
D
Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Tandon
R K
RK
D002780:Cholestasis, Intrahepatic / Q000150:complications*; D005221:Fatigue / Q000209:etiology* / Q000628:therapy; D006801:Humans; D011788:Quality of Life