title: Urinary tract infections caused by endemic multi-resistant Enterobacter cloacae in a dialysis and transplantation unit.
abstract: In the period 1994-1998, 42 multi-resistant Enterobacter cloacae isolates responsible for urinary tract infections (UTIs) were obtained from children hospitalized in our dialysis and transplantation unit. E. cloacae isolates obtained between 1994 and 1996 were susceptible to aminoglycosides, carbapenems and fluoroquinolones, whereas E. cloacae isolates obtained between 1997 and 1998 were susceptible to carbapenems and fluoroquinolones, only. All isolates were characterized by use of the polymerase chain reaction-based random amplification of polymorphic DNA and pulsed-field gel electrophoresis. It was found that the majority of multiresistant E. cloacae isolates obtained during 1997-1998, and all isolates obtained during 1994-1996, belonged to predominant clones A or B. These strains were responsible for gastrointestinal tract colonization and UTI of renal transplant recipients for several years, and persisted as endemic E. cloacae strains in the dialysis and transplantation unit from 1994 to 1998.
authors.affiliation: The Children's Memorial Health Institute, Warsaw, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Kamińska
authors.forename: J
authors.initials: J
authors.lastname: Patzer
authors.forename: D
authors.initials: D
authors.lastname: Dzierzanowska
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000209:etiology*; D004196:Disease Outbreaks; D018432:Drug Resistance, Multiple; D016521:Electrophoresis, Gel, Pulsed-Field; D016972:Enterobacter cloacae / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008826:Microbial Sensitivity Tests; D011044:Poland / Q000453:epidemiology; D019105:Random Amplified Polymorphic DNA Technique; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000209:etiology*