Chromatin: a connection between loops and barriers?
A genetic screen for proteins that can block the spread of silenced heterochromatin has identified components of the nuclear pores with potential barrier activity. These results suggest that formation of loops of chromatin anchored to the pore could be one mechanism of barrier function.
Kamakaka
Rohinton T
RT
Unit on Chromatin and Transcription, NICHD/NIH, Bldg. 18T, Rm. 106, 18 Library Drive, Bethesda, MD 20892, USA. Rohinton@helix.nih.gov
D002843:Chromatin / Q000235:genetics*; D015825:Chromosomes, Fungal / Q000235:genetics; D015966:Gene Expression Regulation, Fungal; D020868:Gene Silencing; D006570:Heterochromatin / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D016615:Telomere / Q000235:genetics
D002843:Chromatin; D006570:Heterochromatin