Irritant potential of triterpenoids from Ficus carica leaves.
The irritant potential of total methanolic extract and five triterpenoids newly isolated from the leaves of Ficus carica investigated by open mouse ear assay. Total methanolic extract, calotropenyl acetate, methyl maslinate and lupeol acetate showed potent and persistent irritant effects.
Saeed
M Asif
MA
Department of Pharmacy, University of the Punjab (Allama Iqbal Campus), 54000, Lahore, Pakistan. moasif1605@hotmail.com
Sabir
A W
AW
D000818:Animals; D005260:Female; D030681:Ficus / Q000737:chemistry*; D007509:Irritants / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D051379:Mice; D018515:Plant Leaves / Q000737:chemistry*; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology*
D007509:Irritants; D014315:Triterpenes