Total synthesis of amaryllidaceae alkaloid buflavine.
A concise synthesis of the amaryllidaceae alkaloid buflavine (1) and its regioisomer (2) involving sequential Meyers' biaryl coupling, enecarbamate formation, and hydrogenation followed by ultimate intramolecular reductive amination is presented.
Hoarau
Christophe
C
Laboratoire de Chimie Organique Physique, UPRESA 8009, Université des Sciences et Technologies de Lille, Bâtiment C3, DUSVA, 59655 Villeneuve d'Ascq Cedex, France.
Couture
Axel
A
Deniau
Eric
E
Grandclaudon
Pierre
P
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D047151:Amaryllidaceae Alkaloids; D001392:Azocines / Q000138:chemical synthesis* / Q000737:chemistry; D032462:Cycadopsida / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure
D000470:Alkaloids; D047151:Amaryllidaceae Alkaloids; D001392:Azocines; C465299:buflavine