title: Discordance between physical symptoms versus perception of severity by women with nausea and vomiting in pregnancy (NVP).
abstract: BACKGROUND: Nausea and vomiting in pregnancy (NVP) is a multifaceted condition that affects more than half of pregnant women and can range in severity from mild nausea to severe dehydration. Presently physicians evaluate mostly physical symptoms of NVP in trying to assess the severity of the condition. The objective of this study was to investigate how factors, other than the physical morbidity of nausea and vomiting, influence self-perception of NVP by affected women. METHODS: Five hundred women with NVP calling a 1-800 NVP Healthline were asked to rate their NVP severity and report their nausea duration and number of vomiting/retching episodes. RESULTS: Nausea and vomiting/retching correlated significantly but very poorly with self-assessment of NVP severity. There was also a correlation between nausea duration and vomiting/retching frequency however the correlations were weak and overall physical symptoms could only explain 14% of the variability of women's feelings and perceptions through multivariate analysis. CONCLUSIONS: Physical symptoms weakly correlate with self-assessment of NVP severity. Other aspects of this condition, most probably psychosocial, influence women's perception of NVP severity.
authors.affiliation: Motherisk Program, Division of Clinical Pharmacology and Toxicology, Department of Pediatrics and Research Institute, The Hospital for Sick Children, Toronto, Department of Pediatrics, Pharmacology, Pharmacy and Medicine, The University of Toronto, Ontario, Canada. gkoren@sickkids.ca
authors.forename: Kiran
authors.initials: MSC
authors.lastname: Chandra K
authors.forename: Laura
authors.initials: MD
authors.lastname: Magee L
authors.forename: Gideon
authors.initials: MD
authors.lastname: Koren G