title: Sicca syndrome associated with Tropheryma whipplei intestinal infection.
abstract: The case of a 61-year-old woman with Whipple's disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipple's disease is discussed.
authors.affiliation: Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy.
authors.forename: Cesare
authors.initials: C
authors.lastname: Bosman
authors.forename: Renata
authors.initials: R
authors.lastname: Boldrini
authors.forename: Giuliana
authors.initials: G
authors.lastname: Borsetti
authors.forename: Sergio
authors.initials: S
authors.lastname: Morelli
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Paglia
authors.forename: Paolo
authors.initials: P
authors.lastname: Visca
mesh_terms: D039903:Actinobacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D000193:Actinomycetales Infections / Q000150:complications / Q000382:microbiology*; D004275:DNA, Ribosomal / Q000032:analysis; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000382:microbiology / Q000648:ultrastructure; D007579:Jejunal Diseases / Q000150:complications / Q000382:microbiology*; D007583:Jejunum; D008875:Middle Aged; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D012859:Sjogren's Syndrome / Q000150:complications / Q000382:microbiology*; D008061:Whipple Disease / Q000150:complications / Q000382:microbiology*
chemical_list: D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S