title: Genetic heterogeneity of Apo CII locus in north India.
abstract: Apolipoprotein CII genotypes were determined in Brahmins, Banias, Jat Sikhs, Khatris, Ramgarhia, Ramdasia and Scheduled Castes of Punjab, North India (n = 930). The Apo CII exhibits three common polymorphic alleles CII*1, CII*2 and CII*3 with pooled frequencies 0.883, 0.114 and 0.003, respectively. CII*3 was absent in Brahmins. Distribution of Apo CII isoforms highlights a considerable variation among different ethnic groups across the world. The average heterozygosity of the Punjabi populations was 0.208. The gene diversity among these population groups was less than 0.1%.
authors.affiliation: Department of Human Biology, Punjabi University, Patiala, India.
authors.forename: Puneet Pal
authors.initials: PP
authors.lastname: Singh
authors.forename: Monica
authors.initials: M
authors.lastname: Singh
authors.forename: Sarabjit S
authors.initials: SS
authors.lastname: Mastana
mesh_terms: D000328:Adult; D000483:Alleles; D053304:Apolipoprotein C-II; D001056:Apolipoproteins C / Q000235:genetics*; D001782:Blood Donors; D002874:Chromosome Mapping; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D005788:Gene Pool; D018740:Genetic Heterogeneity; D005828:Genetics, Population; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged
chemical_list: D053304:Apolipoprotein C-II; D001056:Apolipoproteins C