title: Actin dynamics: tropomyosin provides stability.
abstract: Tropomyosin stabilizes actin filaments, while ADF/cofilin promotes their disassembly. These two proteins compete with each other for binding to the actin filament, providing a critical balance for actin assembly in vivo.
authors.affiliation: Department of Cell Biology, Washington University School of Medicine, Campus Box 8228, 660 S. Euclid Ave., St. Louis, MO 63110, USA. john.cooper@cellbiology.wustl.edu
authors.forename: John A
authors.initials: JA
authors.lastname: Cooper
mesh_terms: D008841:Actin Cytoskeleton / Q000648:ultrastructure; D000199:Actins / Q000378:metabolism*; D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D002465:Cell Movement; D011554:Pseudopodia / Q000502:physiology* / Q000648:ultrastructure; D014335:Tropomyosin / Q000378:metabolism*
chemical_list: D000199:Actins; D014335:Tropomyosin