title: Increased levels of platelet-associated immunoglobulin G in a patient with mixed connective tissue disease.
abstract: We report the case of a 71-year-old Japanese woman with mixed connective tissue disease and increased levels of platelet-associated immunoglobulin G. After administration of oral prednisolone, platelet-associated immunoglobulin G levels decreased with a simultaneous increase in the number of platelets, suggesting that the thrombocytopenia observed in this patient was mediated by immune mechanisms. This is the first reported case of increased platelet-associated immunoglobulin G levels in a patient with mixed connective tissue disease.
authors.affiliation: Department of Internal Medicine, Nanokaichi Municipal Hospital, 643 Nanokaichi, Tomioka, Gunma 370-2343, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Nojima
authors.forename: M
authors.initials: M
authors.lastname: Mori
mesh_terms: D000368:Aged; D001792:Blood Platelets / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008947:Mixed Connective Tissue Disease / Q000097:blood / Q000276:immunology* / Q000473:pathology; D010976:Platelet Count; D011239:Prednisolone / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000188:drug therapy
chemical_list: D007074:Immunoglobulin G; D011239:Prednisolone