title: Acute methyl salicylate toxicity complicating herbal skin treatment for psoriasis.
abstract: We present an interesting case of salicylism arising from the use of methyl salicylate as part of a herbal skin cream for the treatment of psoriasis. A 40-year-old man became quite suddenly and acutely unwell after receiving treatment from an unregistered naturopath. Methyl salicylate (Oil of Wintergreen) is widely available in many over the counter topical analgesic preparations and Chinese medicated oils. Transcutaneous absorption of the methyl salicylate was enhanced in this case due to the abnormal areas of skin and use of an occlusive dressing. The presence of tinnitus, vomiting, tachypnoea and typical acid/base disturbance allowed a diagnosis of salicylate toxicity to be made. Our patient had decontaminated his skin prior to presentation, limiting the extent of toxicity and was successfully treated with rehydration and establishment of good urine flow.
authors.affiliation: Emergency Department, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW, Australia. anthony.bell@bartsandthelondon.nhs.uk
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Bell
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Duggin
mesh_terms: D000328:Adult; D029001:Herbal Medicine; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000628:therapy*; D012459:Salicylates / Q000633:toxicity*; D012869:Skin Absorption
chemical_list: D012459:Salicylates; C033069:methyl salicylate