Osmotic myelinolysis in a normonatremic patient.
Osmotic demyelination syndrome is usually associated with hyponatremia or rapid correction of this condition. The prognosis is usually fatal. We treated a 34-year-old chronic renal failure patient who did not have hyponatremia but developed severe pontine myelinolysis demonstrated with MRI. Serial MRI revealed gradual reduction of the lesions over 2 months. This case demonstrates that osmotic demyelination syndrome is not always associated with hyponatremia, and that, although the prognosis is usually poor, some patients recover.
Kilinç
Münire
M
Başkent University Faculty of Medicine, Neurology Department Fevzi Cakmak Caddesi, Ankara, Turkey. munirekilinc@superonline.com
Benli
Ulkü Sibel
US
Can
Ufuk
U
D000328:Adult; D006801:Humans; D007010:Hyponatremia / Q000097:blood; D007676:Kidney Failure, Chronic / Q000097:blood; D008279:Magnetic Resonance Imaging; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000097:blood* / Q000175:diagnosis* / Q000628:therapy; D012964:Sodium / Q000097:blood*
D012964:Sodium