Reversed-phase HPLC of polymer additives with multiple on-line spectroscopic analysis (UV, IR, (1)H NMR and MS).
The reversed-phase chromatography of a number of polymer additives has been undertaken with on-line characterisation via a combination of diode array UV, (1)H NMR, IR spectroscopy and mass spectrometry. This combination of spectrometers enabled the on-flow collection of full UV, (1)H NMR, IR and mass spectra for a range of common polymer additives in amounts ranging from ca. 230 to 900 micro g on-column. The practical difficulties associated with multiple hyphenation and potential future developments are discussed.
Louden
Dave
D
LGC, The Heath, Runcorn, Cheshire, WA7 4QD, UK.
Handley
Alan
A
Lenz
Eva
E
Sinclair
Ian
I
Taylor
Steve
S
Wilson
Ian D
ID
D002084:Butylated Hydroxytoluene / Q000031:analogs & derivatives / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003408:Cresols / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D009862:Online Systems; D011108:Polymers / Q000032:analysis* / Q000737:chemistry; D012680:Sensitivity and Specificity; D020313:Specialty Uses of Chemicals / Q000032:analysis* / Q000302:isolation & purification; D013053:Spectrophotometry / Q000379:methods; D013055:Spectrophotometry, Infrared / Q000379:methods
D003408:Cresols; D011108:Polymers; D020313:Specialty Uses of Chemicals; D002084:Butylated Hydroxytoluene; C076883:topanol A