title: Domain fishing: a first step in protein comparative modelling.
abstract: To optimize the search for structural templates in protein comparative modelling, the query sequence is split into domains. The initial list of templates for each domain, extracted from PFAM plus PDB and SCOP, is then ranked according to sequence identity (%ID), coverage and resolution. If %ID is less than 30, secondary structure matching is used to filter out false templates.
  
  
  BACKGROUND
  http://www.bmm.icnet.uk/~3djigsaw/dom_fish
authors.affiliation: Biomolecular Modelling Laboratory, Cancer Research, UK. b.contreras-moreira@cancer.org.uk
authors.forename: B
authors.initials: B
authors.lastname: Contreras-Moreira
authors.forename: P A
authors.initials: PA
authors.lastname: Bates
mesh_terms: D000465:Algorithms; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods*; D011381:Programming Languages; D011506:Proteins / Q000737:chemistry* / Q000235:genetics; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
chemical_list: D011506:Proteins