title: Deduction of paternity index from DNA mixture.
abstract: Determination of individual genotypes in DNA mixture remains a challenge in forensic science. Using an approach of mixture of distributions, this article provides formula for calculation of paternity index (PI) in cases where only tissue mixture of the mother and alleged father, the genotypes of the mother and child, but not that of the alleged father are available. The formula has been used to solve a real case using mother's vaginal tissue contaminated with semen from alleged father.
authors.affiliation: Department of Biochemistry, The Chinese University of Hong Kong, NT, Hong Kong SAR, PR China.
authors.forename: Xiang Hai
authors.initials: XH
authors.lastname: Liao
authors.forename: Tai Shang
authors.initials: TS
authors.lastname: Lau
authors.forename: Karenda Fai Ngor
authors.initials: KF
authors.lastname: Ngan
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
mesh_terms: D016172:DNA Fingerprinting; D005260:Female; D005838:Genotype; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008432:Mathematical Computing; D010334:Paternity; D010641:Phenotype; D011336:Probability