Delayed effects of 1,2-epoxypropyltrimethylammonium chloride on behavioral reactions in rats.
We studied immediate and delayed effects of intraventricular injection of 1,2-epoxypropyltrimethylammonium chloride on behavioral reactions in rats. Apomorphine-induced yawning increased and orientation and exploratory activity was improved 144 h postinjection, which indicates activation of the brain dopaminergic system during this period.
Plyashkevich
Yu G
YG
Laboratory of Bioscreening, ASINEKS Company, Moscow.
Barsegyan
G G
GG
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004852:Epoxy Compounds / Q000008:administration & dosage / Q000633:toxicity*; D005106:Exploratory Behavior / Q000187:drug effects; D007276:Injections, Intraventricular; D008297:Male; D009949:Orientation / Q000187:drug effects; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D015000:Yawning / Q000187:drug effects
D004852:Epoxy Compounds; D000644:Quaternary Ammonium Compounds; C045006:glycidyl trimethylammonium