title: Enantioselective total synthesis of (+)-testudinariol a using a new nickel-catalyzed allenyl aldehyde cyclization.
abstract: An enantioselective total synthesis of (+)-testudinariol A was completed. A new nickel-catalyzed allenyl aldehyde cyclization was developed in the approach. In addition, an asymmetric anti aldol reaction and a two-directional oxocarbenium ion/vinyl silane condensation were employed as key steps.
authors.affiliation: Department of Chemistry, Wayne State University, Detroit, Michigan 48202, USA.
authors.forename: Kande K D
authors.initials: KK
authors.lastname: Amarasinghe
authors.forename: John
authors.initials: J
authors.lastname: Montgomery
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D009532:Nickel / Q000737:chemistry*; D013237:Stereoisomerism; D014315:Triterpenes / Q000138:chemical synthesis*
chemical_list: D000447:Aldehydes; D014315:Triterpenes; C465964:testudinariol A; D009532:Nickel