Domain fishing: a first step in protein comparative modelling.
To optimize the search for structural templates in protein comparative modelling, the query sequence is split into domains. The initial list of templates for each domain, extracted from PFAM plus PDB and SCOP, is then ranked according to sequence identity (%ID), coverage and resolution. If %ID is less than 30, secondary structure matching is used to filter out false templates.


BACKGROUND
http://www.bmm.icnet.uk/~3djigsaw/dom_fish
Contreras-Moreira
B
B
Biomolecular Modelling Laboratory, Cancer Research, UK. b.contreras-moreira@cancer.org.uk
Bates
P A
PA
D000465:Algorithms; D030562:Databases, Protein; D016247:Information Storage and Retrieval / Q000379:methods*; D011381:Programming Languages; D011506:Proteins / Q000737:chemistry* / Q000235:genetics; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
D011506:Proteins