title: Insulin-dependent diabetes mellitus in 2 male African American children after Kawasaki disease.
abstract: Two children with insulin-dependent diabetes mellitus (IDDM) presented with diabetic ketoacidosis within 4 months of being diagnosed with Kawasaki disease (KD). Both patients were African American males younger than 4 years of age. Immune markers associated with the autoimmune cause of diabetes were not detectable in these patients at the time of diagnosis with IDDM. In 1 patient, the immune markers were repeated 6 months after diagnosis but remained negative. Both patients currently require approximately 1 unit of insulin/kg/d. Occurrence of IDDM after KD is rare; we could find no such reports in the English literature. The cause of diabetes in these 2 patients remains elusive, as does the cause of KD.
authors.affiliation: Section of Pediatric Endocrinology and Metabolism, University of South Alabama, Mobile, Alabama 36617-7722, USA. sbhowmick@usouthal.edu
authors.forename: Samar K
authors.initials: SK
authors.lastname: Bhowmick
authors.forename: Benjamin
authors.initials: B
authors.lastname: Estrada
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Rettig
mesh_terms: D044383:Black People; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*; D001741:Black or African American