Preparation of monodisperse controlled release microcapsules.
Since the handling of many active agents in its pure form has many problems, microencapsulation is used to have better properties in the product. With the patented BRACE-Processes it is possible to encapsulate a very wide range of materials in monodisperse Microspheres or Microcapsules in a diameter range of 50-6000 microm with a very narrow size distribution. The Microsphere Units from BRACE can be customer tailored to the materials and all necessary specifications as FDA, GMP/GLP, EX, CIP, WIP etc. The throughput of the BRACE Microsphere Units ranges between 10 ml per h (small laboratory scale) up to over 1000 l per h (production scale) while the production cost are very low, especially if compared directly to competitive processes as spray-drying or fluidized bed coating.
Brandau
Thorsten
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BRACE GmbH, Taunusring 50, Alzenau, Germany. info@brace.de
D002214:Capsules; D004339:Drug Compounding / Q000295:instrumentation / Q000379:methods*; D005079:Excipients; D008863:Microspheres; D010316:Particle Size; D013501:Surface-Active Agents
D002214:Capsules; D005079:Excipients; D013501:Surface-Active Agents