Heme oxygenase-1 gene transfer prevents CD95/FasL-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway.
Ke
B
B
Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine, 10833 LeConte Avenue, Los Angeles, CA 90095, USA.
Shen
X-D
XD
Buelow
R
R
Melinek
J
J
Amersi
F
F
Gao
F
F
Ritter
T
T
Volk
H D
HD
Busuttil
R W
RW
Kupiec-Weglinski
J W
JW
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002248:Carbon Monoxide / Q000502:physiology*; D002460:Cell Line; D006085:Graft Survival / Q000502:physiology*; D006367:HeLa Cells; D006419:Heme Oxygenase (Decyclizing) / Q000235:genetics* / Q000378:metabolism; D051547:Heme Oxygenase-1; D006801:Humans; D016031:Liver Transplantation / Q000502:physiology*; D008297:Male; D008565:Membrane Proteins; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D011994:Recombinant Proteins / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015398:Signal Transduction; D014162:Transfection; D014184:Transplantation, Homologous; D019014:fas Receptor / Q000502:physiology*
D008565:Membrane Proteins; D011994:Recombinant Proteins; D019014:fas Receptor; D002248:Carbon Monoxide; C496541:HMOX1 protein, human; D006419:Heme Oxygenase (Decyclizing); D051547:Heme Oxygenase-1