title: Neuropathologic and MR imaging correlation in a neonatal case of cerebellar cortical dysplasia.
abstract: Little documentation of the correlation between MR imaging findings in isolated cerebellar cortical dysplasia (CCD) and its neuropathologic characteristics exists in the recent literature. We documented a postmortem neuropathologic study of a clinically and radiologically well-documented case of CCD in a neonate with severe hypotonia and status epilepticus. MR imaging revealed a global vermian hypoplasia with marked cortical dysplasia. CCD was associated with a voluminous heterotopic mass. The postmortem neuropathologic study confirmed vermian hypoplasia and CCD, which consisted of right cerebellar cortical polymicrogyria with subcortical heterotopia. CCD is a pathologic entity that could be well diagnosed with MR imaging even in the neonatal period.
authors.affiliation: Department of Neuroradiology, Hôpital Roger Salengro, Chru Lille, France.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Soto-Ares
authors.forename: Louise
authors.initials: L
authors.lastname: Devisme
authors.forename: Sylvie
authors.initials: S
authors.lastname: Jorriot
authors.forename: Berengere
authors.initials: B
authors.lastname: Deries
authors.forename: Jean P
authors.initials: JP
authors.lastname: Pruvo
authors.forename: Marie M
authors.initials: MM
authors.lastname: Ruchoux
mesh_terms: D002525:Cerebellar Cortex / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D002526:Cerebellar Diseases / Q000175:diagnosis*; D002973:Cleidocranial Dysplasia; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008279:Magnetic Resonance Imaging; D011859:Radiography; D013223:Statistics as Topic