Cyclization of 1,6-enynes with allylic chromate species.
[reaction: see text] Treatment of 1,6-enynes with tetramethallylchromate induces a cyclization reaction with concurrent introduction of a methallyl group. A catalytic amount of CrCl(3) combined with methallylmagnesium chloride also achieves this cyclization process. The resultant cyclic organometallic species undergo further functionalization upon reaction with electrophiles.
Nishikawa
Toshihiro
T
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Japan.
Shinokubo
Hiroshi
H
Oshima
Koichiro
K