Germination inhibitory constituents from Erigeron annuus.
(5-Butyl-3-oxo-2,3-dihydrofuran-2-yl)-acetic acid was isolated from the flowers of Erigeron annuus as one of four germination inhibitory constituents. Its structure was determined by analysis of MS and NMR spectroscopic data. Three known compounds, 3-hydroxy-pyran-4-one, 4-hydroxycinnamic acid, and 3,4-dihydroxycinnamic acid methyl ester were also identified as active constituents. These compounds showed 50% inhibitory effects (IC(50)) on the germination of lettuce seed at concentrations of 2.13+/-0.03, 12.85+/-0.56, 4.97+/-0.24, and 4.87+/-0.25 mM, respectively. 4-Hydroxybenzoic acid was used as a positive control, displaying an IC(50) value of 4.02+/-0.39 mM.
Oh
Hyuncheol
H
Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, 570-749, Chonbuk, Republic of Korea.
Lee
Sunyoung
S
Lee
Ho-Sub
HS
Lee
Dong-Heon
DH
Lee
Seung Yeob
SY
Chung
Hun-Taeg
HT
Kim
Tae Soo
TS
Kwon
Tae-Oh
TO
D019659:Asteraceae / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D018525:Germination / Q000187:drug effects*; D020128:Inhibitory Concentration 50; D018545:Lactuca / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010936:Plant Extracts / Q000494:pharmacology*; D012639:Seeds / Q000187:drug effects
D010936:Plant Extracts