title: Acanthamoeba keratitis in Pondicherry.
abstract: Acanthamoeba keratitis is a potentially devastating infection of the cornea caused by the free-living amoebae, Acanthamoeba species. During the period from 1997 to 2000, a total of 136 corneal scrapings from clinically suspected cases were screened and examined for the presence of the Acanthamoeba. On examination of the direct smear by microscopy, 11 out of 136 cases were positive for Acanthamoeba. Eight patients were males and 3 were females. The age of these patients ranged from 15 to 57 years. All of these cases were agricultural workers who did not use contact lens. Four cases gave a history of injury to the eye and 1 patient gave a history of applying cow dung on the eye after the injury. Rest of the patients did not give any history of trauma or wearing contact lenses. The patients were treated with topical application of neosporin ointment. Many of our cases had complications such as poor vision (all 11 cases had 6/60 or less), scar formation (3 cases), opacity (5 cases) and corneal perforation (2 cases). This report documents for the first time the cases of Acanthamoeba keratitis in Pondicherry.
authors.affiliation: Jawaharlal Institute of Postgraduate Medical Education & Research, Pondicherry.
authors.forename: S C
authors.initials: SC
authors.lastname: Parija
authors.forename: M R
authors.initials: MR
authors.lastname: Prakash
authors.forename: V A
authors.initials: VA
authors.lastname: Rao
authors.forename: R J
authors.initials: RJ
authors.lastname: Vellaniparambil
mesh_terms: D015823:Acanthamoeba Keratitis / Q000188:drug therapy / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000382:Agricultural Workers' Diseases / Q000188:drug therapy / Q000209:etiology*; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001414:Bacitracin / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D009355:Neomycin / Q000627:therapeutic use; D011112:Polymyxin B / Q000627:therapeutic use
chemical_list: D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D001414:Bacitracin; C001816:bacitracin zinc, neomycin sulfate, polymyxin B, drug combination; D009355:Neomycin; D011112:Polymyxin B