Periodontal diseases and HIV infection.
The workshop considered six related questions about periodontal changes seen in HIV infection. 1) To what extent are specific periodontal changes associated with HIV? 2) Are conventional periodontal diseases modified by HIV infection? The changes associated with HIV appear to be modified presentations of conventional diseases. Research should identify initiation and progression factors for necrotizing diseases. 3) What is the role of geography and transmission groups? These questions cannot be answered without greater standardisation of research methods. 4) Has the epidemiology of these changes changed with the advent of new therapies? The data required to answer this question should be available soon but this question is irrelevant to the vast majority of people with HIV. 5) What pathogens are involved in periodontal changes seen in HIV infection? The role of Candida spp. and other potential pathogens requires further investigation. 6) What management protocols are suitable for the periodontal diseases? The significance of periodontal diseases among people with HIV in developing countries is not known. Further research is needed of the effectiveness of interventions especially necrotizing disease in developing countries. The quality of research of these diseases would be enhanced by standardized approaches. A list of relevant variables might prevent their omission from studies.
Robinson
Peter G
PG
Dental Institute of Guy's, King's and St Thomas', King's College London, UK. peter.g.robinson@sheffield.ac.uk
Adegboye
A
A
Rowland
R W
RW
Yeung
S
S
Johnson
N W
NW
D023241:Antiretroviral Therapy, Highly Active; D002180:Candidiasis, Oral / Q000150:complications / Q000503:physiopathology; D002985:Clinical Protocols; D003906:Developing Countries; D018450:Disease Progression; D004890:Erythema / Q000150:complications; D005882:Gingival Diseases / Q000150:complications; D005892:Gingivitis, Necrotizing Ulcerative / Q000150:complications; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology / Q000635:transmission; D006801:Humans; D009336:Necrosis; D010510:Periodontal Diseases / Q000150:complications* / Q000503:physiopathology / Q000517:prevention & control; D010518:Periodontitis / Q000150:complications