Struma ovarii associated with pseudo-Meigs' syndrome and elevated serum CA 125.
BACKGROUND
Struma ovarii, presenting as pseudo-Meigs' syndrome with an elevated CA 125 level, is a rare condition.


METHODS
A 65-year-old patient presented with ascites, hydrothorax, right ovarian mass, and elevated CA 125 level. These findings were suspicious for an ovarian malignancy. The mass was removed and revealed struma ovarii, a specialized ovarian teratoma composed predominantly of mature thyroid tissue. In the setting of ascites and hydrothorax, the condition is known as pseudo-Meigs' syndrome. This is the second reported case in the English language literature of pseudo-Meigs' syndrome with an elevated CA 125 level resulting from struma ovarii.


CONCLUSIONS
Struma ovarii is a rare cause of ascites, hydrothorax, and an elevated CA 125 level.
Huh
Julie J
JJ
Department of Gynecology and Obstetrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.
Montz
F J
FJ
Bristow
Robert E
RE
D000368:Aged; D001201:Ascites / Q000209:etiology* / Q000276:immunology; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D006876:Hydrothorax / Q000209:etiology* / Q000276:immunology; D008539:Meigs Syndrome / Q000209:etiology; D013330:Struma Ovarii / Q000150:complications* / Q000276:immunology
D018394:CA-125 Antigen