Plethysmographic curve analysis and response to exercise in normal subjects, hypertension, and cardiac failure.
Occlusion plethysmographic recordings were obtained on 26 subjects prior to and immediately following repeated venous occlusions. A simple method of approximating the curve shape by 2 straight lines is described. The results indicate that, following an initial occlusion, the height of subsequent curves is reduced and the angulation between the 2 lines approximating the curves changes in a way that indicates that the principal mechanism is venous shunting. The degree of shunting was quantified by taking the relative percentage change in shape of the 2 lines approximating the curve, i.e., the percentage shunt. Venous shunting is shown to be much more marked after hand exercise than at rest in normal subjects and in those with heart failure or hypertension.
Woolfson
Peter I
PI
Department of Medicine, Stepping Hill Hospital, Hazel Grove, Stockport, UK. peter@meem.demon.co.uk
Pullan
Brian R
BR
Lewis
Philip S
PS
D000328:Adult; D000368:Aged; D002310:Cardiomyopathy, Alcoholic / Q000150:complications; D003250:Constriction; D015444:Exercise; D005080:Exercise Test; D005260:Female; D005542:Forearm / Q000098:blood supply* / Q000503:physiopathology*; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D017202:Myocardial Ischemia / Q000150:complications; D010991:Plethysmography / Q000379:methods*; D012016:Reference Values; D018924:Vascular Capacitance; D014655:Vascular Resistance; D014661:Vasoconstriction; D014680:Veins / Q000503:physiopathology; D018487:Ventricular Dysfunction, Left / Q000150:complications