title: Intrathoracic extramedullary hematopoiesis arising in marble bone disease. Clarifying the genetic disease mechanism.
abstract: We report a man with intrathoracic extramedullary hematopoiesis accompanied by marble bone disease who underwent thoracoscopic resection safely and definitively, followed by a radionuclide scan. Although intrathoracic extramedullary hematopoiesis is almost always accompanied by hemolytic anemia, this man's hematological data normalized. A consensus on the tumor genesis mechanism has yet to be reached, but the existence of marble bone disease in our case throws new light on the genetic mechanism in intrathoracic extramedullary hematopoiesis.
authors.affiliation: Division of the General Thoracic Surgery, Takarazuka Municipal Hospital, 4-5-1 Kohama, Takarazuka 665-0827, Japan.
authors.forename: Norihisa
authors.initials: N
authors.lastname: Shigemura
authors.forename: Akinori
authors.initials: A
authors.lastname: Akashi
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Nakagiri
mesh_terms: D000368:Aged; D006411:Hematopoiesis, Extramedullary / Q000235:genetics*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D010022:Osteopetrosis / Q000097:blood*; D013902:Radiography, Thoracic; D013906:Thoracoscopy; D013908:Thoracotomy / Q000379:methods*; D014057:Tomography, X-Ray Computed