title: Configurational assignment of alpha-chiral carboxylic acids by complexation to dimeric Zn-porphyrin: host-guest structure, chiral recognition and circular dichroism.
abstract: A circular dichroic (CD) excition chirality method based on host-guest chiral recognition has been developed to determine the absolute configuration of carboxylic acids with an alpha-stereogenic center; an amide C = O-->Zn coordination, identified by infrared spectroscopy and computations, is involved in this complexation.
authors.affiliation: Department of Chemistry, Columbia University, New York, NY 10027, USA.
authors.forename: Gloria
authors.initials: G
authors.lastname: Proni
authors.forename: Gennaro
authors.initials: G
authors.lastname: Pescitelli
authors.forename: Xuefei
authors.initials: X
authors.lastname: Huang
authors.forename: Nazia Q
authors.initials: NQ
authors.lastname: Quraishi
authors.forename: Koji
authors.initials: K
authors.lastname: Nakanishi
authors.forename: Nina
authors.initials: N
authors.lastname: Berova
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D009010:Monte Carlo Method; D011166:Porphyrins / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D015032:Zinc / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D011166:Porphyrins; D015032:Zinc