title: Coexistence of inversion 16 and the Philadelphia chromosome in patients with acute myelogenous leukemia.
abstract: The coexistence of the Philadelphia chromosome and inversion 16 abnormality in de novo acute myelogenous leukemia (AML) has only rarely been reported. We report the case of a 23-year-old man with these cytogenetic abnormalities. He is in a durable remission following intensive chemotherapy. The literature on this subject is reviewed.
authors.affiliation: Zalmen A. Arlin Cancer Institute and Department of Medicine, New York Medical College, Valhalla 10595, USA.
authors.forename: Ahmad D
authors.initials: AD
authors.lastname: Siddiqui
authors.forename: Zahra S
authors.initials: ZS
authors.lastname: Sheikh
authors.forename: Delong
authors.initials: D
authors.lastname: Liu
authors.forename: Karen
authors.initials: K
authors.lastname: Seiter
mesh_terms: D000328:Adult; D007446:Chromosome Inversion; D002885:Chromosomes, Human, Pair 16; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D010677:Philadelphia Chromosome