title: [Acute severe colitis with recto-vaginal fistula during treatment with non-steroidal anti-inflammatory agents].
abstract: BACKGROUND
  We report the case of severe colitis occurring during treatment with non-steroid anti-inflammatories (NSAI).
  
  
  METHODS
  A 57 year-old woman was hospitalized for lumbar pain that had not been relieved by AINS, tramadol and then morphine. The patient presented with septic shock and peritonitis by rectal perforation, followed by acute rectorrhagia. The endoscopic aspect evoked Crohn's disease with a recto-vaginal fistula. Progression was further complicated by two episodes of collapse because of acute rectorrhagia, requiring hemostasis colectomy and abdominal-perineal amputation.
  
  
  CONCLUSIONS
  The diagnosis retained was AINS-induced colitis complicated by acute colectasia on a fecaloma with recto-vaginal fistula.
authors.affiliation: Service de Médecine Interne II, Hôpital Saint-Esprit, Route de Villeneuve 47923 Agen. Bertrand.Tissot@agen.aquisante.fr
authors.forename: B
authors.initials: B
authors.lastname: Tissot
authors.forename: A
authors.initials: A
authors.lastname: Lamy
authors.forename: F
authors.initials: F
authors.lastname: Perraudeau
authors.forename: J L
authors.initials: JL
authors.lastname: Manouvrier
authors.forename: Y
authors.initials: Y
authors.lastname: Imbert
mesh_terms: D000208:Acute Disease; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced* / Q000150:complications; D005260:Female; D006801:Humans; D008875:Middle Aged; D012006:Rectovaginal Fistula / Q000209:etiology*; D012720:Severity of Illness Index
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal