title: Alterations in acetylcholinesterase isoenzyme pattern of hippocampus after septal lesions in rat brain.
abstract: The effect of septal lesions upon the AChE (EC 3.1.1.7) isoenzymic pattern in the hippocampus of the rat brain was studied 1-3 months after surgery by means of polyacrylamide disc electrophoresis. Alterations in the isoenzymic pattern were found in the membrane-bound but not in the soluble fraction of the enzyme. In addition to the two slowly migrating bands seen in the membrane-bound AChE fraction of the normal hippocampus, the fast-migrating isoenzyme becomes visible.
authors.affiliation: Department of Biochemistry of Nervous System and Muscle, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Oderfeld-Nowak
authors.forename: J
authors.initials: J
authors.lastname: Skangiel-Kramska
mesh_terms: D000110:Acetylcholinesterase / Q000032:analysis / Q000378:metabolism*; D000818:Animals; D001923:Brain Chemistry; D004591:Electrophoresis, Polyacrylamide Gel; D006624:Hippocampus / Q000737:chemistry / Q000201:enzymology*; D007527:Isoenzymes / Q000032:analysis / Q000378:metabolism; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012016:Reference Values; D020665:Septum of Brain / Q000502:physiology* / Q000601:surgery; D013995:Time
chemical_list: D007527:Isoenzymes; D000110:Acetylcholinesterase