Low-salt bowel cleansing preparation (LoSo Prep) as preparation for colonoscopy: a pilot study.
BACKGROUND
Currently available colon cleansing preparations are often poorly tolerated.


OBJECTIVE
To evaluate the efficacy of a low-volume, low-salt preparation for colonoscopy.


METHODS
This was a pilot study in patients scheduled for colonoscopy. The preparation consisted of 34 g of magnesium citrate and four bisacodyl tablets the day before the procedure, and one bisacodyl suppository on the morning of the procedure.


RESULTS
Twenty patients (age range, 49-81 years; all males) were entered into the study. There were no significant side-effects associated with the preparation. All rated the taste as 'tolerable or better'. The examination was considered to be adequate, with no limitations, in 17 patients (85%), and was scored as good to excellent (no solid stool) in 11 (55%), acceptable (small amounts of solid stool) in six (30%) and poor in three (15%: two in-patients and one out-patient). Importantly, two of the failures then received a standard polyethylene glycol preparation and again failed to show adequate colon preparation.


CONCLUSIONS
This pilot study showed that the low-salt colon cleansing preparation was an effective alternative preparation for colonoscopy.
Verghese
V J
VJ
Department of Medicine, Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA.
Ayub
K
K
Qureshi
W
W
Taupo
T
T
Graham
D Y
DY
D000284:Administration, Oral; D000285:Administration, Rectal; D000368:Aged; D000369:Aged, 80 and over; D001726:Bisacodyl / Q000008:administration & dosage*; D002400:Cathartics / Q000008:administration & dosage*; D019343:Citric Acid / Q000008:administration & dosage*; D003113:Colonoscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage*; D017060:Patient Satisfaction; D010865:Pilot Projects; D013649:Taste
D002400:Cathartics; D009942:Organometallic Compounds; D001726:Bisacodyl; D019343:Citric Acid; C110422:magnesium citrate