title: A rare association of primary biliary cirrhosis and pernicious anemia.
abstract: Primary biliary cirrhosis is often associated with autoimmune diseases. However, an association between primary biliary cirrhosis and pernicious anemia has rarely been reported. We report a patient with primary biliary cirrhosis associated with pernicious anemia and autoimmune gastritis. The patient was a 64-year-old Japanese woman who had been diagnosed as having primary biliary cirrhosis 5 years previously. She was readmitted with jaundice and macrocytic anemia. The diagnosis of pernicious anemia was confirmed by the low level of serum vitamin B12 and the presence of anti-parietal cell antibody and anti-intrinsic factor antibody. Pernicious anemia should be regarded as a possible complication of primary biliary cirrhosis.
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Aoyama
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakugawa
authors.forename: Hiroki
authors.initials: H
authors.lastname: Nakasone
authors.forename: Tomofumi
authors.initials: T
authors.lastname: Nakayoshi
authors.forename: Akiko
authors.initials: A
authors.lastname: Kinjo
authors.forename: Maki
authors.initials: M
authors.lastname: Tamayose
authors.forename: Hajime
authors.initials: H
authors.lastname: Higa
authors.forename: Eriko
authors.initials: E
authors.lastname: Uema
authors.forename: Takayuki
authors.initials: T
authors.lastname: Chinen
authors.forename: Ryosaku
authors.initials: R
authors.lastname: Tomiyama
authors.forename: Nobufumi
authors.initials: N
authors.lastname: Uchima
authors.forename: Yukino
authors.initials: Y
authors.lastname: Kugai
authors.forename: Fukunori
authors.initials: F
authors.lastname: Kinjo
authors.forename: Atsushi
authors.initials: A
authors.lastname: Saito
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kinjo
mesh_terms: D000752:Anemia, Pernicious / Q000150:complications*; D001327:Autoimmune Diseases / Q000150:complications; D005260:Female; D005756:Gastritis / Q000150:complications; D006801:Humans; D008099:Liver / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000150:complications*; D008875:Middle Aged; D013270:Stomach / Q000473:pathology