[Prognostic significance of tumor size in the survival of patients with advanced gastric carcinoma].
OBJECTIVE
To determine the prognostic significance of size tumor in the survival of patients with advanced gastric carcinoma.


METHODS
This retrospective study evaluated 95 patients with advanced gastric adenocarcinoma with a diameter smaller than 7 centimeters (Group I) and 85 cases with lesions equal or greater than 7 centimeters (Group II) whom underwent radical gastrectomy with lymphadenectomy D0-D1 (n=148) or D2-D3-D4 (n=32) at Belen Hospital, Trujillo, Peru, between 1966 and 1998.


RESULTS
The median age of the Group I and II was of 58.1 12.9 and 58.5 15.3 years, respectively. The patients of the group II had a lower level of seric hemoglobin (p=0.007) and more frequency of lesions Borrmann type II and IV (p= 0.003). Using the log-rank test, there was no statistically significant difference with relation to five-year survival between both groups using the multivariate analysis of Cox regression. There was not statistically significance difference between the size tumoral and the survival but there were independent factors statistically related with the survival: depth of invasion (p=0.017) and lymph nodes compromised (p=0.014).


CONCLUSIONS
Clinically the size of the tumor was not a factor to take as parameter in the prediction of the actuarial survival in patients with advanced gastric cancer.
Díaz Plasencia
J A
JA
Departamento de Cirugía del Hospital Belén de Trujillo.
Yan-Quiroz
E F
EF
Burgos-Chávez
O A
OA
Santillán-Medina
J P
JP
Stewart-Vilela Guillén
E
E
Rojas-Vergara
A M
AM
D000206:Actuarial Analysis; D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010166:Palliative Care; D010568:Peru / Q000453:epidemiology; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D016019:Survival Analysis