Area-to-amplitude ratio of the terminal phase of the belly-tendon detected motor unit potentials could be used to recognize reinnervated motor units.
Besides the increased number of fibres, the reinnervated motor units (MUs) are characterised by an increased scattering the end-plates, greater desynchronization in the fibres' activation, greater dispersion in the diameters of the MU fibres and thus in propagation velocities along them. As a result, desynchronization in the moments, at which the excitation waves reach the fibres' ends, increases in reinnervated MUs. The possibility to recognize reinnervated MUs in short (hand) muscles on the basis of changes in duration of the terminal (second) phase of the belly-tendon detected motor unit potentials (MUPs) was examined by numerical experiments. A convolution model that took into account the finite fibre length, was used to calculate MUPs for distances typical of surface detection. It was shown that the ratio between the area of the terminal phase and its amplitude, as a measure of duration of the terminal phase, was sensitive to desynchronisation of the waves of excitation. The ratio was independent of the distance from the MU axis and of the volume conductor properties. Basing on the results obtained, we can conclude that the ratio reflects main functional compensations in reinnervated MUs and could be used for discrimination between reinnervated and normal MUs.
Dimitrova
N A
NA
Centre of Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria. ngdim@iph.bio.bas.bg
Disselhorst-Klug
C
C
Dimitrov
G V
GV
Rau
G
G
D004576:Electromyography; D019054:Evoked Potentials, Motor / Q000502:physiology*; D006801:Humans; D008959:Models, Neurological; D009045:Motor Endplate / Q000503:physiopathology; D018485:Muscle Fibers, Skeletal / Q000502:physiology; D017729:Presynaptic Terminals / Q000502:physiology*; D020127:Recovery of Function / Q000502:physiology; D013708:Tendon Injuries / Q000503:physiopathology*; D013710:Tendons / Q000294:innervation* / Q000503:physiopathology*; D013997:Time Factors