title: Neonatal mydriasis: intravenous lidocaine adverse reaction.
abstract: Lidocaine (a sodium channel blocker) serves as an antiepilepsy drug in neonates. We present a neonate with a seizure disorder who acutely developed pupillary mydriasis secondary to lidocaine overdose. We suggest adding this side effect to the list of untoward effects of lidocaine and to the differential diagnosis of fixed dilated pupils in neonates treated with lidocaine.
authors.affiliation: Neuro-Pediatric Unit, Shaare Zedek Medical Center, Jerusalem, Israel. itberg@szmc.org.il
authors.forename: Itai
authors.initials: I
authors.lastname: Berger
authors.forename: Avraham
authors.initials: A
authors.lastname: Steinberg
authors.forename: Yechtiel
authors.initials: Y
authors.lastname: Schlesinger
authors.forename: Mordechai
authors.initials: M
authors.lastname: Seelenfreund
authors.forename: Michael S
authors.initials: MS
authors.lastname: Schimmel
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects*; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D003937:Diagnosis, Differential; D062787:Drug Overdose; D004359:Drug Therapy, Combination; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D015878:Mydriasis / Q000139:chemically induced* / Q000175:diagnosis*; D010634:Phenobarbital / Q000627:therapeutic use; D010672:Phenytoin / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; D000927:Anticonvulsants; D010672:Phenytoin; D008012:Lidocaine; D010634:Phenobarbital