Analgesic and anti-inflammatory effects of the aqueous extract of leaves of Persea americana mill (lauraceae).
The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesses analgesic and anti-inflammatory effects.
Adeyemi
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Department of Pharmacology, College of Medicine, University of Lagos, PMB 12003, Lagos, Nigeria. cmul@rcl.nig.com
Okpo
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Ogunti
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D000700:Analgesics / Q000494:pharmacology*; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D005260:Female; D019770:Lauraceae / Q000737:chemistry*; D008297:Male; D051379:Mice; D009549:Nigeria; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D010936:Plant Extracts