Sicca syndrome associated with Tropheryma whipplei intestinal infection.
The case of a 61-year-old woman with Whipple's disease-associated sicca complex is reported. Tropheryma whipplei infection was diagnosed by histological and ultrastructural examination of the jejunal mucosa and sequence analysis of the bacterial 16S ribosomal DNA. The role of vitamin A malabsorption in sicca complex secondary to Whipple's disease is discussed.
Bosman
Cesare
C
Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy.
Boldrini
Renata
R
Borsetti
Giuliana
G
Morelli
Sergio
S
Paglia
Maria Grazia
MG
Visca
Paolo
P
D039903:Actinobacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D000193:Actinomycetales Infections / Q000150:complications / Q000382:microbiology*; D004275:DNA, Ribosomal / Q000032:analysis; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000382:microbiology / Q000648:ultrastructure; D007579:Jejunal Diseases / Q000150:complications / Q000382:microbiology*; D007583:Jejunum; D008875:Middle Aged; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D012859:Sjogren's Syndrome / Q000150:complications / Q000382:microbiology*; D008061:Whipple Disease / Q000150:complications / Q000382:microbiology*
D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S