Hox Genes: it's all a matter of context.
Recent studies provide compelling new evidence that Hox gene effects depend on fine-structure spatial and temporal information. Further, in a specific cell type, only one or a few downstream genes may mediate Hox morphogenetic functions. If this is generally true, it will have important implications for how Hox regulatory networks operate and evolve.
Lohmann
Ingrid
I
Department of Biology, 0349, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
McGinnis
William
W
D000818:Animals; D004330:Drosophila / Q000196:embryology / Q000254:growth & development; D004625:Embryo, Nonmammalian / Q000502:physiology; D005801:Genes, Homeobox; D009024:Morphogenesis / Q000235:genetics