title: Dermatomyositis associated with membranous nephropathy in a 43-year-old female.
abstract: A 43-year-old woman was admitted to our hospital for myalgic pain and erythema of the face and thighs. She had been diagnosed with dermatomyositis at another hospital 8 years earlier and proteinuria had developed suddenly. Renal histological examination revealed membranous nephropathy. Membranous nephropathy associated with dermatomyositis is very rare. To date, malignant disease has not been detected in our patient, but the serum level of CA125, a tumor marker, has been elevated to 1,097 U/ml. The increased CA125 level is related to the degree of proteinuria and after prednisolone and cyclosporine therapy, proteinuria and the CA125 level gradually decreased.
authors.affiliation: Department of Internal Medicine, Kinashi Ohbayashi Hospital, Kagawa, Japan. akashi16@excite.co.jp
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Akashi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Inoh
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Gamo
authors.forename: Makoto
authors.initials: M
authors.lastname: Kinashi
authors.forename: Seiichi
authors.initials: S
authors.lastname: Ohbayashi
authors.forename: Hayashi
authors.initials: H
authors.lastname: Miyake
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Kurata
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D018394:CA-125 Antigen / Q000097:blood; D016572:Cyclosporine / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D003882:Dermatomyositis / Q000150:complications* / Q000188:drug therapy; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D011507:Proteinuria / Q000097:blood / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D003879:Dermatologic Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone