title: Reactivation of retinal toxoplasmosis despite evidence of immune response to highly active antiretroviral therapy.
abstract: We report a case of retinal toxoplasmosis that occurred in a patient with acquired immunodeficiency syndrome who had a previous diagnosis of cerebral toxoplasmosis, despite the patient having had a robust immune response to highly active antiretroviral therapy. Clinical decisions about whether to discontinue secondary prophylaxis for opportunistic infections continue to be challenging.
authors.affiliation: Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. stout002@mc.duke.edu
authors.forename: Jason E
authors.initials: JE
authors.lastname: Stout
authors.forename: James C
authors.initials: JC
authors.lastname: Lai
authors.forename: Julia
authors.initials: J
authors.lastname: Giner
authors.forename: Carol Dukes
authors.initials: CD
authors.lastname: Hamilton
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology / Q000469:parasitology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D008297:Male; D012164:Retinal Diseases / Q000209:etiology / Q000276:immunology / Q000469:parasitology*; D014123:Toxoplasmosis / Q000209:etiology / Q000276:immunology*