On-line coupling of miniaturized solid-phase extraction and microcolumn liquid-phase separations.
On-line coupling of miniaturized solid-phase extraction methods and microcolumn separation techniques are reviewed. A conventional solid-phase micro-extraction device and fiber-in-tube solid-phase extraction was employed as the sample preparation method. In the fiber-in-tube technique, a novel fibrous polymeric material was introduced as the extraction medium for the microscale sample preparation step which could be directly coupled with microcolumn liquid-phase separation systems, such as microcolumn liquid chromatography, capillary electrophoresis, and capillary electrochromatography. The applications of these hyphenated systems, consisting of the sample preparation and separation processes, are also reviewed.
Saito
Yoshihiro
Y
School of Materials Science, Toyohashi University of Technology, Toyohashi 441-8580, Japan.
Jinno
Kiyokatsu
K
D002197:Capillary Action; D002853:Chromatography, Liquid / Q000379:methods; D008904:Miniaturization / Q000379:methods*; D009862:Online Systems