title: Fluids and the neurosurgical patient.
abstract: Few human data exist concerning the impact of fluid administration on brain pathophysiology. Those factors that influence water movement into the brain are examined, in order to provide reasonable recommendations for peri-operative fluid management in the patients with brain pathology.
authors.affiliation: Institute of Anesthesiology and Intensive Care, University of Milano, Department of Anesthesia and Intensive Care, San Raffaele Hospital, Via Olgettina, 60 20132, Milano, Italy. tommasino.concezione@hsr.it
authors.forename: Concezione
authors.initials: C
authors.lastname: Tommasino
mesh_terms: D001812:Blood-Brain Barrier; D001929:Brain Edema / Q000209:etiology / Q000517:prevention & control; D000077324:Crystalloid Solutions; D004232:Diuretics / Q000627:therapeutic use; D018495:Fluid Shifts; D005440:Fluid Therapy; D006400:Hematocrit; D006438:Hemodilution; D006801:Humans; D007262:Infusions, Intravenous; D007427:Intracranial Pressure; D007430:Intraoperative Care; D007552:Isotonic Solutions; D019635:Neurosurgical Procedures / Q000009:adverse effects; D009994:Osmolar Concentration; D009997:Osmotic Pressure; D010952:Plasma Substitutes; D011182:Postoperative Care; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage; D014883:Water-Electrolyte Imbalance / Q000209:etiology / Q000628:therapy
chemical_list: D000077324:Crystalloid Solutions; D004232:Diuretics; D007552:Isotonic Solutions; D010952:Plasma Substitutes; D012462:Saline Solution, Hypertonic