title: The influence of environmental pollution on the amount of glycosoaminoglycans in the tissue of palatine tonsils.
abstract: In this study, we investigated persons exposed to high and low air pollution caused by metals. This investigation was done against the background of changes in the connective tissue of palatine tonsils. We evaluated the qualitative and quantitative composition of glycosoaminoglycans (GAG) isolated from palatine tonsils. GAGs were separated by column chromatography. We found that as the total amount of GAGs increased, the amount of heparin and chondroitin sulphate also increased, whereas the amount of hyaluronic acid, dermatane sulphate, heparane sulphate and keratane sulphate decreased. The changes observed in the amount of GAGs in the tissue of palatine tonsils can influence the incidence of infections of the upper airways.
authors.affiliation: Department of Food and Nutrition, Silesian Academy of Medicine, Sosnowiec, Poland. chemogan@infomed.slam.katowice.pl
authors.forename: Maria
authors.initials: M
authors.lastname: Wardas
authors.forename: Tatiana
authors.initials: T
authors.lastname: Gierek
authors.forename: Jarosław
authors.initials: J
authors.lastname: Paluch
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Pawłowska-Góral
authors.forename: Jan
authors.initials: J
authors.lastname: Pilch
authors.forename: Jarosław
authors.initials: J
authors.lastname: Markowski
mesh_terms: D000328:Adult; D000388:Air / Q000032:analysis; D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D000397:Air Pollution / Q000032:analysis; D002850:Chromatography, Gel; D005260:Female; D006025:Glycosaminoglycans / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D019570:Inhalation Exposure; D008297:Male; D019216:Metals, Heavy / Q000032:analysis; D008875:Middle Aged; D014066:Palatine Tonsil / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology
chemical_list: D000393:Air Pollutants; D006025:Glycosaminoglycans; D019216:Metals, Heavy