title: Some possible longer-term ocular changes following excimer laser refractive surgery.
abstract: While the short- and medium-term refractive and acuity results of excimer laser refractive surgery may now be generally satisfactory, the relatively brief history of the procedures involved (around 10 years or less) means that those concerned with eye care must remain vigilant to the possibility of longer-term problems. This paper reviews some relevant studies of potential post-surgical effects, including imperfect corneal healing and recovery of innervation, reduced corneal sensitivity and dry eye problems, changes in corneal rigidity leading to slow refractive change, possibly misleading reductions in measured intraocular pressure, and retinal and vitreous pathology.
authors.affiliation: Department of Optometry and Neuroscience, UMIST, Manchester, UK.
authors.forename: Laura
authors.initials: L
authors.lastname: Oliveira-Soto
authors.forename: W Neil
authors.initials: WN
authors.lastname: Charman
mesh_terms: D003315:Cornea / Q000473:pathology / Q000601:surgery*; D016510:Corneal Neovascularization; D004728:Endothelium, Corneal / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure; D015603:Keratinocytes / Q000473:pathology; D054018:Lasers, Excimer; D009216:Myopia / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D018903:Photorefractive Keratectomy / Q000009:adverse effects / Q000379:methods; D012086:Reoperation; D012160:Retina / Q000473:pathology; D013666:Tears / Q000378:metabolism; D013997:Time Factors; D014822:Vitreous Body / Q000473:pathology; D014945:Wound Healing