title: Characterization of ISRgn1, a novel insertion sequence of the IS3 family isolated from a bacteriocin-negative mutant of Ruminococcus gnavus E1.
abstract: ISRgn1, an insertion sequence of the IS3 family, has been identified in the genome of a bacteriocin-negative mutant of Ruminococcus gnavus E1. The copy number of ISRgn1 in R. gnavus E1, as well as its distribution among phylogenetically E1-related strains, has been determined. Results obtained suggest that ISRgn1 is not indigenous to the R. gnavus phylogenetic group but that it can transpose in this bacterium.
authors.affiliation: Mixis France, Faculte de Medicine Necker-Enfants Malades, 75730 Paris Cedex 15, France. ana.gomez@mixis.fr
authors.forename: Ana
authors.initials: A
authors.lastname: Gomez
authors.forename: Monique
authors.initials: M
authors.lastname: Ladire
authors.forename: Francoise
authors.initials: F
authors.lastname: Marcille
authors.forename: Michelle
authors.initials: M
authors.lastname: Nardi
authors.forename: Michel
authors.initials: M
authors.lastname: Fons
mesh_terms: D001421:Bacteria, Anaerobic / Q000235:genetics* / Q000378:metabolism; D001430:Bacteriocins / Q000378:metabolism*; D001483:Base Sequence; D004251:DNA Transposable Elements; D018628:Gene Dosage; D006094:Gram-Positive Bacteria / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D009154:Mutation; D017422:Sequence Analysis, DNA
chemical_list: D001430:Bacteriocins; D004251:DNA Transposable Elements