Calcium channel blocker induced gingival overgrowth.
Gingival overgrowth occurs with phenytoin, cyclosporin, and calcium antagonists. It can be disfiguring and painful. The prevalence of gingival overgrowth with the use of calcium antagonists may be as high as 38%. The prevalence with nifedipine may be greater than with other calcium blockers. Overgrowth occurs 3.3-times more commonly in men than in women. Plaque control is necessary. Some patients may require gingival surgery.
Prisant
L Michael
LM
Department of Medicine, Section of Hypertension & Clinical Pharmacology, Medical College of Georgia, Augusta 30912, USA.
Herman
Wayne
W
D002121:Calcium Channel Blockers / Q000009:adverse effects*; D005886:Gingival Hypertrophy / Q000139:chemically induced*; D006801:Humans; D009543:Nifedipine / Q000009:adverse effects
D002121:Calcium Channel Blockers; D009543:Nifedipine