title: [Methadone poisoning in a 1-year-old child treated by continuous infusion of naloxone].
abstract: Methadone is a synthetic narcotic used in opioid dependent situations. Child intoxications are harmful, sometimes responsible for death.
  
  
  METHODS
  An one-year-old infant was seen in the emergency room, two hours after accidental methadone ingestion. He presented with coma, myosis and respiratory depression. After intubation, symptoms disappeared with naloxone injection. For maintaining this child safe, naloxone was given by continuous infusion during 48 hours.
  
  
  CONCLUSIONS
  Patients, families and professionals should be informed of the risks of methadone intoxication. Owing to methadone long duration of action, initial injection of naloxone, the specific opioid antagonist, must be followed by continuous infusion.
authors.affiliation: Service de pédiatrie-néonatologie, centre hospitalier sud-francilien, 91014 Evry, France. antoine.leblanc@easynet.fr
authors.forename: A
authors.initials: A
authors.lastname: Leblanc
authors.forename: N
authors.initials: N
authors.lastname: Benbrick
authors.forename: M H
authors.initials: MH
authors.lastname: Moreau
mesh_terms: D000059:Accidents; D000367:Age Factors; D004630:Emergencies; D006801:Humans; D007223:Infant; D008297:Male; D008691:Methadone / Q000506:poisoning*; D009270:Naloxone / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D009270:Naloxone; D008691:Methadone