Co-stimulatory requirements of effector T cells at inflammatory sites.
There is a growing appreciation of the importance of T cell costimulation at inflammatory sites. Here, we briefly review the literature on the subject, and describe recent pertinent findings in our model of herpes simplex keratitis.
Xu
Min
M
Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA. minsu@pitt.edu
Lepisto
Andrew J
AJ
Hendricks
Robert L
RL
D000818:Animals; D006801:Humans; D007249:Inflammation / Q000276:immunology*; D016849:Keratitis, Herpetic / Q000276:immunology*; D008954:Models, Biological; D050378:T-Lymphocytes, Regulatory / Q000502:physiology*