Poxviruses and apoptosis: a time to die.
All known apoptosis modulators in poxviruses have been shown to function as inhibitors. The mechanistic classes of these poxvirus-encoded inhibitors are quite diverse, and indicate that a wide variety of distinct host proteins in cellular apoptotic pathways have been targeted for inhibition by individual poxviruses.
Everett
Helen
H
Department of Biochemistry, University of Alberta, 4-63 Medical Sciences Building, Edmonton, T6G 2H7, Alberta, Canada. heverett@biochem.ualberta.ca
McFadden
Grant
G
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D006801:Humans; D051379:Mice; D011212:Poxviridae / Q000472:pathogenicity*; D011213:Poxviridae Infections / Q000276:immunology* / Q000821:virology; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism; D014774:Virulence
D014764:Viral Proteins