title: Causative factors, surgical treatment and outcome of incisional hernia after liver transplantation.
abstract: BACKGROUND
  Little is known about the incidence and causes of herniation, and the results of hernia repair in patients undergoing liver transplantation. Likewise, nothing is known about the best surgical approach for hernia repair.
  
  
  METHODS
  A retrospective analysis was conducted of the occurrence of incisional hernia in 290 patients who had liver transplantation between 1990 and 2000, and survived more than 6 months. Follow-up data were obtained from medical records and the outpatient service. Patients were evaluated for various clinical and surgical factors. Hernias were analysed with respect to localization, type of surgical repair and recurrence rate.
  
  
  RESULTS
  Some 17 per cent of the transplanted patients experienced an incisional hernia. Risk factors were acute rejection with affiliated steroid bolus therapy (P = 0.025), a low platelet count after transplantation (P = 0.048), and a transverse abdominal incision with upper midline approach (P = 0.04). Hernias were mainly located at the junction of the transverse and midline incision (P < 0.001) and the recurrence rate was highest here (P = 0.007). Prosthetic hernia repair achieved the lowest rate of recurrence and did not increase the incidence of infectious complications.
  
  
  CONCLUSIONS
  Improved immunosuppression should avoid early steroid bolus therapy after transplantation. A low platelet count promotes herniation. Transverse abdominal incision seems to be the best approach for liver transplantation. Prosthetic hernia repair does not increase the complication rate.
authors.affiliation: Klinik für Allgemein- und Transplantationschirurgie, Zentrum Chirurgie, Universitätsklinikum Essen, Essen, Germany. hermann.janszen@t-online.de
authors.forename: H
authors.initials: H
authors.lastname: Janssen
authors.forename: R
authors.initials: R
authors.lastname: Lange
authors.forename: J
authors.initials: J
authors.lastname: Erhard
authors.forename: M
authors.initials: M
authors.lastname: Malagó
authors.forename: F W
authors.initials: FW
authors.lastname: Eigler
authors.forename: C E
authors.initials: CE
authors.lastname: Broelsch
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D006555:Hernia, Ventral / Q000209:etiology* / Q000601:surgery; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000601:surgery; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome