Trimethoprim-induced aseptic meningitis in an adolescent male.
Drug-induced aseptic meningitis attributable to trimethoprim alone has only rarely been documented in the literature. A previously healthy adolescent male presented to our hospital with recurrent headaches, photophobia, and meningismus after serially starting and stopping trimethoprim. Cerebrospinal fluid studies revealed elevated white blood cell counts with a polymorphonuclear predominance. This case is the second documented report of trimethoprim-induced aseptic meningitis in a pediatric patient.
Redman
Richard C
RC
University of Washington School of Medicine, Seattle, Washington 98125, USA. rredman@u.washington.edu
Miller
John Bernard
JB
Hood
Margaret
M
DeMaio
James
J
D000152:Acne Vulgaris / Q000188:drug therapy; D000293:Adolescent; D000890:Anti-Infective Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008582:Meningitis, Aseptic / Q000139:chemically induced* / Q000175:diagnosis; D014295:Trimethoprim / Q000009:adverse effects*
D000890:Anti-Infective Agents; D014295:Trimethoprim