Erythrinaline alkaloids and antimicrobial flavonoids from Erythrina latissima.
The seed pods of Erythrina latissima yielded erysotrine, erysodine, syringaresinol, vanillic acid, a new erythrina alkaloid, (+)-10,11-dioxoerysotrine, which was lethal to brine shrimp and 2-(5'-hydroxy-3'-methoxy phenyl)-6-hydroxy-5-methoxybenzofuran, which showed strong antimicrobial activity against the yeast spores, Gram-positive and Gram-negative bacteria. The root bark gave four known pterocarpans which showed moderate to strong antifungal activity against the yeast spores and three known flavonoids showed antimicrobial activity against all test microorganisms.
Wanjala
Cornelius C
CC
Juma
Benard F
BF
Bojase
Gomotsang
G
Gashe
Berhanu A
BA
Majinda
Runner R
RR
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004895:Erythrina / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects
C464951:2-(5'-hydroxy-3'-methoxyphenyl)-6-hydroxy-5-methoxybenzofuran; D000470:Alkaloids; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001572:Benzofurans; D005419:Flavonoids