Efficient synthesis of ningalin C.
[reaction: see text] A concise and efficient synthesis of the permethyl derivative of the marine alkaloid ningalin C (2) has been accomplished. The key step involves the formation of a pyrrolinone from an aminoquinone in one pot. An efficient route for the synthesis of the key aminoquinone has also been developed.
Namsa-aid
Anucha
A
Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand.
Ruchirawat
Somsak
S
D000470:Alkaloids / Q000138:chemical synthesis*; D000818:Animals; D011758:Pyrroles / Q000138:chemical synthesis*; D011809:Quinones / Q000138:chemical synthesis*; D014561:Urochordata
D000470:Alkaloids; D011758:Pyrroles; D011809:Quinones; C465246:ningalin C