The influence of environmental pollution on the amount of glycosoaminoglycans in the tissue of palatine tonsils.
In this study, we investigated persons exposed to high and low air pollution caused by metals. This investigation was done against the background of changes in the connective tissue of palatine tonsils. We evaluated the qualitative and quantitative composition of glycosoaminoglycans (GAG) isolated from palatine tonsils. GAGs were separated by column chromatography. We found that as the total amount of GAGs increased, the amount of heparin and chondroitin sulphate also increased, whereas the amount of hyaluronic acid, dermatane sulphate, heparane sulphate and keratane sulphate decreased. The changes observed in the amount of GAGs in the tissue of palatine tonsils can influence the incidence of infections of the upper airways.
Wardas
Maria
M
Department of Food and Nutrition, Silesian Academy of Medicine, Sosnowiec, Poland. chemogan@infomed.slam.katowice.pl
Gierek
Tatiana
T
Paluch
Jarosław
J
Pawłowska-Góral
Katarzyna
K
Pilch
Jan
J
Markowski
Jarosław
J
D000328:Adult; D000388:Air / Q000032:analysis; D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D000397:Air Pollution / Q000032:analysis; D002850:Chromatography, Gel; D005260:Female; D006025:Glycosaminoglycans / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D019570:Inhalation Exposure; D008297:Male; D019216:Metals, Heavy / Q000032:analysis; D008875:Middle Aged; D014066:Palatine Tonsil / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology
D000393:Air Pollutants; D006025:Glycosaminoglycans; D019216:Metals, Heavy