A case of secondary myocardial lymphoma presenting with ventricular tachycardia.
Malignant lymphoma can involve the cardiac cavity or myocardium as a mass. Clinical symptoms of its cardiac involvement are usually absent or nonspecific, making the diagnosis of the cardiac involvement very difficult before death. We experienced a patient with secondary myocardial non-Hodgkin's lymphoma presenting with sustained ventricular tachycardia (VT) as a primary clinical problem. A 39-yr-old woman visited our hospital because of dyspnea and palpitation for 7 days. Physical examination revealed rapid heart beat with variable intensity of the first heart sound and soft mass in the lower abdomen. VT with a cycle length of 480 msec was recorded in resting 12-lead electrocardiogram. Two well-circumscribed hypo-echogenic round masses were demonstrated in the interventricular septum and left ventricular posterior wall. Cytological examination of aspirated pericardial fluid and percutaneous needle biopsy of the abdominal mass revealed a diffuse large cell type non-Hodgkin's lymphoma. Myocardial masses and ventricular tachycardia resolved with chemotherapy using cyclophosphamide, adriamycin, vincristine and prednisone regimen. To our best knowledge, the same case as ours has not been reported previously.
Cho
Jeong-Gwan
JG
Division of Cardiology, Department of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, Korea. chojg@unitel.co.kr
Ahn
Young-Keun
YK
Cho
Sang-Hee
SH
Lee
Je-Jung
JJ
Chung
Ik-Joo
IJ
Park
Moo-Rim
MR
Kim
Hyeoung-Joon
HJ
Jeong
Myung-Ho
MH
Park
Jong-Chun
JC
Kang
Jung-Chaee
JC
D000008:Abdominal Neoplasms / Q000556:secondary; D000328:Adult; D001707:Biopsy, Needle; D002037:Bundle-Branch Block; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006338:Heart Neoplasms / Q000473:pathology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000175:diagnosis / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*; D017180:Tachycardia, Ventricular / Q000209:etiology* / Q000503:physiopathology