title: Application of the U and gamma' models in binary sweet taste mixtures.
abstract: The U and Gamma' models of sensory interactions, successfully applied in olfaction for several years, are tested here using data from published studies on sweetness. The models are subsequently tested on new data obtained in studies of binary mixtures of four sodium sulfamates. The U model allows for the estimation of a global interaction, whereas the Gamma' model allows for the distinction between that which is due to an intrinsic interaction in the mixture itself and that which may be due to the power function exponents in the mixture. The models give satisfactory predictions for observed phenomena of sweet taste suppression, synergism or pure additivity. Additionally, they appear to be more suitable than other models recently applied in taste, particularly the equiratio model. Application of the models to the sulfamate mixtures, reveals additivity for sodium cyclohexylsulfamate (cyclamate)/potassium cyclohexylsulfamate and sodium cyclohexylsulfamate/sodium exo-2-norbornylsulfamate, respectively; whereas for sodium cyclohexylsulfamate/sodium 3-bromophenylsulfamate, the models revealed a slight hypo addition which is simply due to the dissimilarity values of the power function exponents of the components.
authors.affiliation: CNRS, Centre Européen des Sciences du Goût, Dijon, France. laffort@cesg.cnrs.fr
authors.forename: P
authors.initials: P
authors.lastname: Laffort
authors.forename: R M
authors.initials: RM
authors.lastname: Walsh
authors.forename: W J
authors.initials: WJ
authors.lastname: Spillane
mesh_terms: D001218:Aspartame / Q000494:pharmacology; D002241:Carbohydrates / Q000737:chemistry / Q000494:pharmacology; D004338:Drug Combinations; D004357:Drug Synergism; D008432:Mathematical Computing; D008954:Models, Biological; D013223:Statistics as Topic; D013451:Sulfonic Acids / Q000737:chemistry* / Q000494:pharmacology*; D013549:Sweetening Agents / Q000737:chemistry* / Q000494:pharmacology*; D013649:Taste
chemical_list: D002241:Carbohydrates; D004338:Drug Combinations; D013451:Sulfonic Acids; D013549:Sweetening Agents; C005741:sulfamic acid; D001218:Aspartame