title: ZrO(2) gel-derived DNA-modified electrode and the effect of lanthanide on its electron transfer behavior.
abstract: A new method of immobilizing deoxyribonucleic acid (DNA) was developed based on sol-gel technique, the resulting DNA-modified electrode was characterized with the cyclic voltammetry. The electrode was used to study the electron transfer of DNA in 1.0 mM potassium ferricyanide system in different concentrations of lanthanum(III), europium(III), and calcium(II). The heterogeneous rate constants of the reduction of Fe(CN)(6)(3-) with and without the above cations were calculated by Tafel equation. The results show that lanthanide ions can increase the electron transfer rate much more than calcium ion.
authors.affiliation: Laboratory of Mesoscopic Materials and Chemistry, Department of Chemistry, Institute of Analytical Science, Nanjing University, Nanjing 210093, China.
authors.forename: Shou-Qing
authors.initials: SQ
authors.lastname: Liu
authors.forename: Jing-Juan
authors.initials: JJ
authors.lastname: Xu
authors.forename: Hong-Yuan
authors.initials: HY
authors.lastname: Chen
mesh_terms: D000818:Animals; D015374:Biosensing Techniques; D002118:Calcium / Q000737:chemistry; D002417:Cattle; D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods; D004566:Electrodes; D004579:Electron Transport; D004867:Equipment Design; D005063:Europium / Q000737:chemistry; D005292:Ferricyanides / Q000737:chemistry*; D005782:Gels; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D010084:Oxidation-Reduction; D012680:Sensitivity and Specificity; D013950:Thymus Gland / Q000737:chemistry; D015040:Zirconium / Q000737:chemistry*
chemical_list: D005292:Ferricyanides; D005782:Gels; D028581:Lanthanoid Series Elements; D005063:Europium; D004247:DNA; D015040:Zirconium; C028541:zirconium oxide; D002118:Calcium; C028033:potassium ferricyanide