title: [Bronchial obstruction and the ideopathic hyper-eosinophilic syndrome].
abstract: The idiopathic hyper-eosinophilic syndrome is defined as a peripheral blood eosinophilia greater than 1.5 x 10(9)/litre present for at least 6 months and associated with visceral involvement. It may only be accepted after carefully excluding the other common or rare causes of hyper-eosinophilia and should remain a diagnosis of exclusion. The associated visceral lesions are multiple and non-specific. Among these neurological, digestive, dermatological and cardiac manifestations are the most frequently described. Whereas pleuro-pulmonary involvement is also common, asthma is rarely reported. We report a case of ideopathic hyper-eosinophilic syndrome presenting as asthma. This was secondary to eosinophilic infiltration of the bronchial mucosa as demonstrated by cytological examination of induced sputum.
authors.affiliation: Unité de Pneumologie, Département de Médecine Aiguë Spécialisée, Hôpital A. Michallon, CHU de Grenoble, Université J. Fourier, Grenoble, France.
authors.forename: A
authors.initials: A
authors.lastname: Boignard
authors.forename: M
authors.initials: M
authors.lastname: Fior-Gozlan
authors.forename: R
authors.initials: R
authors.lastname: Gressin
authors.forename: F
authors.initials: F
authors.lastname: Louis
authors.forename: C
authors.initials: C
authors.lastname: Brambilla
authors.forename: D
authors.initials: D
authors.lastname: Seigneurin
authors.forename: G
authors.initials: G
authors.lastname: Devouassoux
mesh_terms: D000328:Adult; D001249:Asthma / Q000209:etiology*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications*; D008297:Male