title: Brain injury-related heterotopic bone formation: treatment strategy and results.
abstract: OBJECTIVE
  Heterotopic bone formation (HO) is a phenomenon occurring in some neurologically injured patients that can adversely affect their rehabilitation. The current study aimed at evaluating functional results and recurrence rates after recurrence of such lesions.
  
  
  METHODS
  The results of 12 excisions of HO in 9 patients were assessed. A single-dose of 750 cGy delivered 24 hr postoperatively was used in seven of nine patients.
  
  
  RESULTS
  One year postintervention, the arc of motion averaged 92.5 degrees in the hips, 66.6 in the knees, and 60 degrees in the elbow. Despite increased uptake on bone scans in all patients, recurrence did not occur in any patient. Ambulation levels improved in four of eight hips. Ease of personal hygiene was improved in all patients, although some patients still require assistance.
  
  
  CONCLUSIONS
  Excision of symptomatic HO is recommended if limitation of joint motion seems to hinder the patient's rehabilitation. Some motor control is desirable to achieve significant improvement in the patient's quality of life. Increased uptake on bone scans is not a contraindication to surgical excision of HO, provided the neurologic status is stabilized.
authors.affiliation: Department of Orthopaedics, Assaf-Harofe Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Zeriffin, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Melamed
authors.forename: D
authors.initials: D
authors.lastname: Robinson
authors.forename: N
authors.initials: N
authors.lastname: Halperin
authors.forename: N
authors.initials: N
authors.lastname: Wallach
authors.forename: O
authors.initials: O
authors.lastname: Keren
authors.forename: Z
authors.initials: Z
authors.lastname: Groswasser
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D011446:Prospective Studies; D011788:Quality of Life; D011859:Radiography; D016059:Range of Motion, Articular; D020127:Recovery of Function; D013997:Time Factors; D016896:Treatment Outcome