[Inhibitory effect of lead ions on cells of some strains of Pseudomonas species bacteria].
The inhibition effect of ionic lead on membrane ATPase activity, transmembrane potential (delta psi) and permeability level of the Pb-sensitive P. fluorescens B894 and Pb-resistant P. fluorescens B4252 bacteria cells have been studied. It have been shown that decreasing ATPase activity and transmembrane potential values and the increasing of permeability by lead are higher for Pb-sensitive strain then for Pb-resistant. It is suggested that mechanism of the ionic lead toxic effect deals with plasma membrane biochemical parameters (ATPase activity, value of delta psi) alterations and interruption of it barrier function.
Gruzina
T G
TG
Ovcharenco Institute of Biocolloid Chemistry, NAS of Ukraine, Kyiv.
Chekhovskaia
T P
TP
Balakina
M N
MN
Ul'berg
Z R
ZR
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors; D002412:Cations; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D007854:Lead / Q000737:chemistry / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D011551:Pseudomonas fluorescens / Q000187:drug effects* / Q000201:enzymology
D002412:Cations; D007854:Lead; D000251:Adenosine Triphosphatases