title: [Paraquat poisoning and hemoperfusion with activated charcoal].
abstract: Paraquat is a common herbicide in Spain. In our country there are a few cases of this intoxication and it presents a high mortality even if the patients ingest a minimal amount. We present two cases of accidental poisoning with paraquat. These patients were admitted three hours after ingestion of toxin. They were treated with with orogastric lavage, activated charcoal, N-acetylcysteine, Fuller's earth, cathartics, support measures and hemoperfusion with activated charcoal. With these treatments both patients had a undetectable levels of paraquat 48 hours after and improvement of their symptoms, gastric and intestinal predominantly . We present the graphics of evolution of the plasma and urine levels of paraquat in both patients. We review the different aspects of treatment and update of this poisoning.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Clínico Universitario de Santiago de Compostela.
authors.forename: A M
authors.initials: AM
authors.lastname: López Lago
authors.forename: C
authors.initials: C
authors.lastname: Rivero Velasco
authors.forename: C
authors.initials: C
authors.lastname: Galban Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: Mariño Rozados
authors.forename: N
authors.initials: N
authors.lastname: Piñeiro Sande
authors.forename: E
authors.initials: E
authors.lastname: Ferrer Vizoso
mesh_terms: D000059:Accidents; D000111:Acetylcysteine / Q000627:therapeutic use; D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use; D002400:Cathartics / Q000627:therapeutic use; D002606:Charcoal / Q000627:therapeutic use*; D007692:Diatomaceous Earth / Q000627:therapeutic use*; D005260:Female; D005440:Fluid Therapy; D005751:Gastric Lavage; D005947:Glucose / Q000627:therapeutic use; D006464:Hemoperfusion; D006801:Humans; D008297:Male; D008875:Middle Aged; D010269:Paraquat / Q000097:blood / Q000506:poisoning* / Q000652:urine; D011041:Poisoning / Q000628:therapy
chemical_list: D000975:Antioxidants; D002400:Cathartics; D002606:Charcoal; D007692:Diatomaceous Earth; D005947:Glucose; D010269:Paraquat; D000111:Acetylcysteine