title: Proteomics goes quantitative: measuring protein abundance.
abstract: Protein-based methodologies are catching up with established DNA-based methods at an astonishing speed. Recent developments in mass spectrometry enable high-throughput automated identification of proteins as is already the case with DNA sequencing methods. Furthermore, methods for the quantitation of relative protein abundance at the protein level are getting more advanced, which should complement gene expression monitoring at the mRNA level.
authors.affiliation: Department Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Hanno
authors.initials: H
authors.lastname: Steen
authors.forename: Akhilesh
authors.initials: A
authors.lastname: Pandey
mesh_terms: D007553:Isotope Labeling / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods* / Q000639:trends; D011506:Proteins / Q000032:analysis* / Q000235:genetics*; D040901:Proteomics; D020539:Sequence Analysis, Protein / Q000379:methods* / Q000639:trends
chemical_list: D011506:Proteins