Gold opens mitochondrial pathways to apoptosis.
McKeage
Mark J
MJ
Division of Pharmacology and Clinical Pharmacology, The University of Auckland, Private Bag 92019, New Zealand. m.mckeage@auckland.ac.nz
D000818:Animals; D018501:Antirheumatic Agents / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects*; D001310:Auranofin / Q000494:pharmacology*; D020169:Caspases / Q000378:metabolism; D006801:Humans; D008928:Mitochondria / Q000187:drug effects* / Q000378:metabolism; D010084:Oxidation-Reduction; D013880:Thioredoxin-Disulfide Reductase / Q000378:metabolism; D013879:Thioredoxins / Q000378:metabolism
D018501:Antirheumatic Agents; D001310:Auranofin; D013879:Thioredoxins; D013880:Thioredoxin-Disulfide Reductase; D020169:Caspases