title: Laparoscopic herniorrhaphy with porcine small intestinal submucosa: a preliminary study.
abstract: BACKGROUND
  Using mesh or a synthetic prosthesis during the laparoscopic repair of inguinal hernias has been demonstrated to be safe and effective. A new material, porcine small intestinal submucosa (SIS mesh), has been successfully used in canine and rodent animal models with excellent results. This mesh is degradable and resorbable with a marked decrease in the possibility of becoming infected. However, the amount of fibroblast ingrowth is equal to that with polypropylene mesh.
  
  
  METHODS
  A comparison was made between this new SIS mesh to repair 15 inguinal hernias in 12 patients and polypropylene mesh used in 12 similar patients. A preperitoneal approach with balloon dissection was used in all patients.
  
  
  RESULTS
  Demographics were similar in both groups. The results were excellent and compared equally. Complications (seroma, discomfort) were minimal in both groups and were similar.
  
  
  CONCLUSIONS
  Porcine small intestinal submucosa, SIS mesh, can be used for laparoscopic repair of inguinal hernias. Long-term follow-up will be necessary to confirm these preliminary results.
authors.affiliation: The Gallbladder & Laparoscopic Surgery Center at Baptist Health System, Miami, FL 33176, USA. D.EdelmanMD@aol.com
authors.forename: David S
authors.initials: DS
authors.lastname: Edelman
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D005260:Female; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D007413:Intestinal Mucosa / Q000637:transplantation*; D007421:Intestine, Small; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011126:Polypropylenes; D013552:Swine
chemical_list: D011126:Polypropylenes