title: Syntheses of Metal Phthalocyanines and Their Photoinactivations on Cancer Cells.
abstract: This paper reported the syntheses of amphiphilic substituted metal phthalocyanines containig sulfonic acid groups and phthalimidomethyl groups (MPcSP, M=Zn or Al(OH), S=-SO(3)(-), P=phthalimidomethyl). We have selected zinc phthalocyanine (Zn-D) as the one with better cell killing potential by an in vitro cell survival assay. Over 90 % tumor cells were killed with 10 mg/L Zn-D, after they were exposed to 12 J/cm(2) red light.
authors.affiliation: Department of Chemistry, Institute of Functional Materials, Fuzhou University, Fuzhou 350002, China.
authors.forename: Er-Sheng
authors.initials: ES
authors.lastname: Liu
authors.forename: Zhi-Fei
authors.initials: ZF
authors.lastname: Dai
authors.forename: Jian-Dong
authors.initials: JD
authors.lastname: Huang
authors.forename: Nai-Sheng
authors.initials: NS
authors.lastname: Chen
authors.forename: Jin-Ling
authors.initials: JL
authors.lastname: Huang
authors.forename: Zi-Qiang
authors.initials: ZQ
authors.lastname: Huang
authors.forename: Jian-Cheng
authors.initials: JC
authors.lastname: Sun