title: Isolation and identification of oligomeric procyanidins from Crataegus leaves and flowers.
abstract: Oligomeric procyanidins were isolated from the leaves and flowers of hawthorn (Crataegus laevigata). A trimer, epicatechin-(4 beta-->8)-epicatechin-(4 beta-->6)-epicatechin, and a pentamer consisting of (-)-epicatechin units linked through C-4 beta/C-8 bonds have been isolated from hawthorn for the first time, in addition to known procyanidins including dimers B-2, B-4 and B-5, trimers C-1 and epicatechin-(4 beta-->6)-epicatechin-(4 beta-->8)-epicatechin, and tetramer D-1. A fraction containing a hexamer was also found.
authors.affiliation: Department of Pharmacy, Division of Pharmacognosy, University of Helsinki, PO Box 56, FIN-00014 Helsinki, Finland.
authors.forename: Ulla
authors.initials: U
authors.lastname: Svedström
authors.forename: Heikki
authors.initials: H
authors.lastname: Vuorela
authors.forename: Risto
authors.initials: R
authors.lastname: Kostiainen
authors.forename: Jari
authors.initials: J
authors.lastname: Tuominen
authors.forename: Juha
authors.initials: J
authors.lastname: Kokkonen
authors.forename: Jussi-Pekka
authors.initials: JP
authors.lastname: Rauha
authors.forename: Into
authors.initials: I
authors.lastname: Laakso
authors.forename: Raimo
authors.initials: R
authors.lastname: Hiltunen
mesh_terms: D044946:Biflavonoids; D002392:Catechin / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D027825:Crataegus / Q000737:chemistry*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D044945:Proanthocyanidins; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D044946:Biflavonoids; D044945:Proanthocyanidins; C017674:procyanidin; D002392:Catechin