title: Putative drug-related pemphigus foliaceus in four dogs.
abstract: Four dogs developed cutaneous lesions following the administration of various antibiotics. Histopathology of the lesions was compatible with pemphigus foliaceus, although apoptotic cells suggestive of erythema multiforme were seen in two cases. In two dogs the lesions resolved after 7.5-8.5 months of immune-suppressive treatment. No recurrence was seen during the follow-up period (3 and 4.5 years). The lesions in the other two dogs resolved within 3 weeks to 3 months following discontinuation of the antibiotic. No recurrence of clinical signs occurred during the follow-up period (1 and 4 years, respectively).
authors.affiliation: Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA. sdwhite@ucdavis.edu
authors.forename: Stephen D
authors.initials: SD
authors.lastname: White
authors.forename: Didier N
authors.initials: DN
authors.lastname: Carlotti
authors.forename: Didier
authors.initials: D
authors.lastname: Pin
authors.forename: Terri
authors.initials: T
authors.lastname: Bonenberger
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Ihrke
authors.forename: Eric
authors.initials: E
authors.lastname: Monet
authors.forename: Koji
authors.initials: K
authors.lastname: Nishifuji
authors.forename: Toshiroh
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Mark G
authors.initials: MG
authors.lastname: Papich
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D004285:Dogs; D003875:Drug Eruptions / Q000175:diagnosis / Q000662:veterinary*; D005260:Female; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D010392:Pemphigus / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents