A comparison study of ultrasound and Xenon-133 hepatic retention ratio in fatty liver.
OBJECTIVE
We compared ultrasound and Xenon-133 hepatic retention ratio to evaluate the accuracy of ultrasound in diagnosing fatty liver.


METHODS
One hundred and forty-six patients with suspected fatty liver were included. All patients underwent an ultrasound study followed by a determination of the Xenon-133 hepatic retention.


RESULTS
Using the Xenon-133 hepatic retention ratio as the diagnostic standard, the overall accuracy of ultrasound in detecting fatty liver was 57.5%, with 100% sensitivity and 6.0% specificity.


CONCLUSIONS
Ultrasound can be used as a first-line screening imaging modality for fatty liver. If the result of ultrasound is equivocal, then Xenon-133 hepatic retention determination should be performed for the diagnosis and management of fatty liver.
Wang
Shyh-Jen
SJ
Department of Nuclear Medicine, Taichung Veterans General Hospital, No. 160, Sec. 3, Taichung Harbor Road, Taichung 407, Taiwan. sjwang@vghtc.gov.tw
Chen
Gran-Hun
GH
Lin
Wan-Yu
WY
Kao
Chia-Hung
CH
Tsai
Shih-Chuan
SC
D000328:Adult; D000368:Aged; D005234:Fatty Liver / Q000175:diagnosis*; D005260:Female; D015902:Gamma Cameras; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008099:Liver / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D008905:Minicomputers; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014980:Xenon Radioisotopes / Q000493:pharmacokinetics
D014980:Xenon Radioisotopes