title: Mifepristone-misoprostol abortion: a trial in rural and urban Maharashtra, India.
abstract: As several important policy questions remain regarding the use of medical abortion in developing countries, we investigated the safety, efficacy, and acceptability of mifepristone-misoprostol abortion in the outpatient family planning departments of two urban hospitals and one rural hospital in India. Nine-hundred women (with gestations of < or =63 days in the urban sites and < or =56 days in the rural site) received 600 mg mifepristone followed 48 h later by 400 microg oral misoprostol in the clinic. Four point four percent or fewer urban women and 1.0% rural women were lost to follow-up. Perfect and typical-use failure rates were low at all sites. While rural women reported fewer side effects at all sites, the vast majority of women were satisfied with their medical abortions. Medical abortion can be offered safely, effectively, and acceptably in the outpatient family planning departments of urban and rural hospitals in India.
authors.affiliation: K.E.M. Hospital, Pune, India.
authors.forename: Kurus
authors.initials: K
authors.lastname: Coyaji
authors.forename: Batya
authors.initials: B
authors.lastname: Elul
authors.forename: Usha
authors.initials: U
authors.lastname: Krishna
authors.forename: Suhas
authors.initials: S
authors.lastname: Otiv
authors.forename: Shubha
authors.initials: S
authors.lastname: Ambardekar
authors.forename: Arti
authors.initials: A
authors.lastname: Bopardikar
authors.forename: Veena
authors.initials: V
authors.lastname: Raote
authors.forename: Charlotte
authors.initials: C
authors.lastname: Ellertson
authors.forename: Beverly
authors.initials: B
authors.lastname: Winikoff
mesh_terms: D000019:Abortifacient Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000028:Abortion, Induced; D000284:Administration, Oral; D000328:Adult; D005193:Family Planning Services; D005260:Female; D006801:Humans; D007194:India; D015735:Mifepristone / Q000008:administration & dosage / Q000627:therapeutic use*; D016595:Misoprostol / Q000008:administration & dosage / Q000627:therapeutic use*; D017060:Patient Satisfaction; D011247:Pregnancy; D011446:Prospective Studies; D012423:Rural Health; D014504:Urban Health
chemical_list: D000019:Abortifacient Agents; D016595:Misoprostol; D015735:Mifepristone