title: 2-[2-Methyl-5-nitro-4-(phenylsulfonylmethyl)imidazol-1-yl]ethanol and 2-methyl-5-nitro-4-phenylsulfonylmethyl-1,3-thiazole.
abstract: The title compounds, C(13)H(15)N(3)O(5)S and C(11)H(10)N(2)O(4)S(2), respectively, both contain a phenylsulfonyl group connected, through a methylene bridge, to either a substituted nitroimidazole or nitro-1,3-thiazole ring. In the imidazole-containing molecule, the nitro and sulfonyl groups are trans relative to the sulfonyl-methyl bond, while in the thiazole-containing molecule, these substituents are cis. The stabilizing interactions within the crystals are also different between the two compounds.
authors.affiliation: Laboratoire de Chimie Organique, UMR CNRS 6517, Faculté de Pharmacie de Marseille, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France.
authors.forename: M D
authors.initials: MD
authors.lastname: Crozet
authors.forename: P
authors.initials: P
authors.lastname: Vanelle
authors.forename: M
authors.initials: M
authors.lastname: Giorgi
authors.forename: A
authors.initials: A
authors.lastname: Gellis
mesh_terms: D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D007093:Imidazoles / Q000737:chemistry*; D008958:Models, Molecular; D013844:Thiazoles / Q000737:chemistry*
chemical_list: C467398:2-(2-Methyl-5-nitro-4-(phenylsulfonylmethyl)imidazol-1-yl)ethanol; C467399:2-methyl-5-nitro-4-phenylsulfonylmethyl-1,3-thiazole; D007093:Imidazoles; D013844:Thiazoles