title: Gem GTPase: between a ROCK and a hard place.
abstract: Gem GTPase is a member of a protein family that includes Rad, Rem and Rem2. Although until recently precious little was known about the function of Gem, recent studies have revealed that Gem may influence cell morphology by antagonising the actions of the Rho GTPase effector protein ROCK I.
authors.affiliation: Abramson Family Cancer Research Institute, BRB II/III, 421 Curie Blvd., University of Pennsylvania, Philadelphia 19104, USA. molson@mail.med.upenn.edu
authors.forename: Michael F
authors.initials: MF
authors.lastname: Olson
mesh_terms: D020558:GTP Phosphohydrolases / Q000378:metabolism*; D047908:Intracellular Signaling Peptides and Proteins; D010766:Phosphorylation; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D013379:Substrate Specificity; D054460:rho-Associated Kinases
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D017346:Protein Serine-Threonine Kinases; D054460:rho-Associated Kinases; D020558:GTP Phosphohydrolases