Fetal hydantoin syndrome with unilateral atypical cleft hand: additional evidence for vascular disruption.
We report on 2 children of a mother treated with phenylhydantoine for post-surgical epilepsy. The hand malformation in one of them was indicative for a vascular disruption sequence.
De Smet
L
L
Department of Orthopaedic Surgery, U.Z. Pellenberg, Lubbeek, Belgium.
Debeer
Ph
P
D000927:Anticonvulsants / Q000009:adverse effects*; D001808:Blood Vessels / Q000187:drug effects* / Q000473:pathology; D002675:Child, Preschool; D019066:Facies; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006228:Hand Deformities, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010672:Phenytoin / Q000009:adverse effects*; D011247:Pregnancy; D011859:Radiography; D013577:Syndrome; D013723:Teratogens / Q000633:toxicity*
D000927:Anticonvulsants; D013723:Teratogens; D010672:Phenytoin