Src and Wnt converge to seal cell's fate.
Src family kinases (SFKs) play many roles in the development and growth of flies and mice. In the July, 2002 issue of Developmental Cell, Bei et al. show that a C. elegans SFK collaborates with the Wnt pathway to specify cell fate in early development.
Taylor
Steve
S
Department of Molecular and Cell Biology, University of California, Berkeley 94720, USA.
Bagrodia
Shubha
S
D000818:Animals; D017173:Caenorhabditis elegans / Q000166:cytology / Q000196:embryology* / Q000201:enzymology / Q000378:metabolism*; D029742:Caenorhabditis elegans Proteins; D002454:Cell Differentiation; D015801:Helminth Proteins / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D015398:Signal Transduction; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D019061:src-Family Kinases / Q000378:metabolism*
D029742:Caenorhabditis elegans Proteins; D015801:Helminth Proteins; C415743:Mes-1 protein, C elegans; D011518:Proto-Oncogene Proteins; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D019061:src-Family Kinases