Serial linkage of target selection for orienting and tracking eye movements.
Many natural actions require the coordination of two different kinds of movements. How are targets chosen under these circumstances: do central commands instruct different movement systems in parallel, or does the execution of one movement activate a serial chain that automatically chooses targets for the other movement? We examined a natural eye tracking action that consists of orienting saccades and tracking smooth pursuit eye movements, and found strong physiological evidence for a serial strategy. Monkeys chose freely between two identical spots that appeared at different sites in the visual field and moved in orthogonal directions. If a saccade was evoked to one of the moving targets by microstimulation in either the frontal eye field (FEF) or the superior colliculus (SC), then the same target was automatically chosen for pursuit. Our results imply that the neural signals responsible for saccade execution can also act as an internal command of target choice for other movement systems.
Gardner
Justin L
JL
Howard Hughes Medical Institute, Department of Physiology, W.M. Keck Foundation Center for Integrative Neuroscience, and Bioengineering Graduate Group, University of California, Box 0444, San Francisco, California 94143, USA. justin@phy.ucsf.edu
Lisberger
Stephen G
SG
D000818:Animals; D001921:Brain / Q000502:physiology*; D005403:Fixation, Ocular / Q000502:physiology; D005625:Frontal Lobe / Q000502:physiology; D008253:Macaca mulatta; D008297:Male; D009039:Motion Perception / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D009949:Orientation / Q000502:physiology*; D010775:Photic Stimulation; D011698:Pursuit, Smooth / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012438:Saccades / Q000502:physiology*; D013477:Superior Colliculi / Q000502:physiology; D014794:Visual Fields / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology