[Characteristics of Crimean-Congo hemorrhagic fever virus circulating in Russia and Central Asia].
Five antigen-positive samples isolated from patients with Crimean-Congo hemorrhagic fever (CCHF) and from Hyalomma marginatum ticks collected in the European part of Russia and three laboratory strains of CCHF isolated in Russia, Uzbekistan, and Tadjikistan were analyzed by reverse transcription-polymerase chain reaction (RT-PCR) and sequencing. Comparison of nucleotide sequences of fragments of CCHF virus genome S segment and phylogenetic analysis of Russian strains showed that all CCHF strains isolated from humans and H. marginatum circulating in Russia were closely related and differed essentially from CCHF variants from other regions. Strains isolated in Uzbekistan and Tadjikistan were most closely related to CCHF strains from China.
Iashina
L N
LN
Petrov
V S
VS
Vyshemirskiĭ
O I
OI
Aristova
V A
VA
Moskvina
T M
TM
L'vov
D K
DK
Petrova
I D
ID
Gutorov
V V
VV
Tiunnikov
G I
GI
Kuzina
I I
II
Samokhvlov
E I
EI
Seregin
S V
SV
Netesov
S V
SV
D000818:Animals; D016679:Genome, Viral; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000235:genetics* / Q000302:isolation & purification; D006479:Hemorrhagic Fever, Crimean / Q000453:epidemiology / Q000635:transmission / Q000821:virology*; D006801:Humans; D010802:Phylogeny; D012426:Russia / Q000453:epidemiology; D013620:Tajikistan / Q000453:epidemiology; D013987:Ticks / Q000821:virology; D014610:Uzbekistan / Q000453:epidemiology