title: [Colorectal cancer: study on 365 cases].
abstract: We report a clinic-endoscopical study about 365 patients, both of sex, between 26-95 years old, with colonoscopic diagnosis of colorectal cancer. Results showed that 61,92% were men and 38,08% women; in 92,60% the disease ocurred over 40 years old. 13,42% had malignant personal history -colorectal cancer, uterus and breast cancer, and others-; 13,97% had bening personal history-colorectal adenoma, cholecystectomy, and others-; Abdomina pain, change in intestinal habits, and bleeding were the moist frequent symptoms, with differences depending of the tumors localization in the colon or rectum. 62,57% of patients had anemia under 10g% of hernoglobin; in 85,23% the fecal occult blood test was positive. On 199 patients, the simple barium enema diagnosed the tumor in 66,33% only; but in the same group, colonoscopy diagnosed the cancer in 96,49% at first examination. In all patients, colonoscopywas excellent for diagnosis of the principal lesion, and for the identification of synchronous neoplasia. On 365 patients, colonoscopy diagnosed the cancer in 98,08% at first examination. The localization of tumors was: 57,63% in left colon (49,47% in rectum and sigmoid colon); 34,21% in the right colon; and 8,16% in transverse. Pathology showed that adenocarcinoma was the most frequent tumor 95,23%; 1,06% mucoid carcinoma; 1,06% epidermoid carcinoma; and 2,65% lymphorna. In 32,05% of cases there were synchronous lesions; 3,01% had other cancer, and 54 patients had 112 polyps (62,50% adenomatous polyp, 6,25% adenoma with non invasive or invasive adenocarcinoma, and 31,25% hiperplastic polyp. Authors emphasize the value of the detection and early diagnosis to decrese the colorectal cancer mortality.
authors.affiliation: Servicio de Gastroenterología, HNERM-IPSS. Facultad de Medicina de la Universidad mayor de San Marcos, Lima, Perú.
authors.forename: A
authors.initials: A
authors.lastname: Celestino
authors.forename: T
authors.initials: T
authors.lastname: Castillo
authors.forename: O
authors.initials: O
authors.lastname: Frisancho
authors.forename: C
authors.initials: C
authors.lastname: Contardo
authors.forename: H
authors.initials: H
authors.lastname: Espejo
authors.forename: C
authors.initials: C
authors.lastname: Tomioka
authors.forename: J
authors.initials: J
authors.lastname: Navarrete
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001464:Barium; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D003108:Colonic Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D003111:Colonic Polyps / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D003113:Colonoscopy / Q000706:statistics & numerical data; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology; D003424:Crohn Disease / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D004241:Diverticulum, Colon / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D009780:Occult Blood; D010568:Peru / Q000453:epidemiology; D012189:Retrospective Studies
chemical_list: D001464:Barium