title: Use of homograft dehydrated temporal fascia in tympanoplasty.
abstract: OBJECTIVE
  To investigate the results of myringoplasty operations using homograft dehydrated fascia temporalis (Tutoplast) and compare these with those performed with autograft fascia temporalis.
  
  
  METHODS
  Prospective cohort.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Forty-three adult patients (> or =18 years of age) with central, dry perforations of pars tensa with intact ossicular chains.
  
  
  METHODS
  Tympanoplasty with an endaural approach and underlay technique was performed. Homograft dehydrated temporal fascia was used in 22 patients, and autograft was used in the remaining 21 patients.
  
  
  METHODS
  Preoperative and postoperative air-bone gap and speech reception threshold levels and postoperative compliance values of the homograft and autograft groups were compared.
  
  
  RESULTS
  Postoperative perforations were encountered in two patients (9.1%) from the homograft group and three patients (14.2%) from the allograft group. Significant postoperative improvements in air-bone gap and speech reception threshold values were detected for both groups (p < 0.05). Although the mean compliance of the tympanic membranes was significantly lower in the homograft group, no statistically significant difference was observed between groups when the postoperative air-bone gap and speech reception threshold values were compared.
  
  
  CONCLUSIONS
  Homograft temporal fascia can be used in tympanoplasty with the same success rate of autograft temporal fascia without impeding hearing. Its main advantages are the reduction in the duration of surgery and the length of preauricular and postauricular incisions. However, the advantages of the dehydrated homograft temporal fascia should be weighed against its cost and risk of transmission of viral and prion-mediated diseases.
authors.affiliation: Department of Otolaryngology, Hacettepe University Medical School, Ankara, Turkey. sarpsarac@ixir.com
authors.forename: Sarp
authors.initials: S
authors.lastname: Saraç
authors.forename: Bülent
authors.initials: B
authors.lastname: Gürsel
mesh_terms: D000328:Adult; D001298:Audiology; D001844:Bone Conduction; D015331:Cohort Studies; D003187:Compliance; D005205:Fascia / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009225:Myringoplasty / Q000379:methods; D011446:Prospective Studies; D013069:Speech Reception Threshold Test; D013703:Temporal Muscle; D014184:Transplantation, Homologous; D014432:Tympanic Membrane / Q000503:physiopathology; D014433:Tympanoplasty