title: [After disappointment regarding secondary cardiac prevention. What is the status of hormone replacement therapy today?].
abstract: ERT (estrogen replacement therapy) or HRT (hormone replacement therapy) can be employed for the prevention/treatment of various hormone-related conditions. The main indications are the treatment of psychovegetative deficits and--in part--primary prevention of osteoporosis. For other (hormone-related) diseases such as certain malignant tumors, the risk may increase under replacement treatment, so that a risk/benefit evaluation should always precede it prescription. Side effects of ERT/HRT include a greater risk of thrombosis and, possibly, a increase in cardiovascular events, so that this form of treatment cannot be recommended at least for the secondary prevention of cardiovascular disease. In general, treatment must be matched to the requirements and wishes of the patient. With increasing age and remitting symptoms, the dose can be reduced. Alternative substances such as phytoestrogens or selective estrogen receptor modulators (SERMs) extend the spectrum of therapeutic options.
authors.forename: F
authors.initials: F
authors.lastname: Geisthövel
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects; D006801:Humans; D008134:Long-Term Care; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology / Q000517:prevention & control*; D015663:Osteoporosis, Postmenopausal / Q000209:etiology / Q000517:prevention & control; D012307:Risk Factors