A two-step conversion of alpha,beta-unsaturated ketones to their alpha-carbalkoxy or alpha-carbamoyl derivatives.
Several enones are converted into their alpha-iodo derivatives in excellent yields and carbonylated with palladium catalysis in the presence of alcohol or amines to the alpha-carbonyl enones in satisfactory yields.
Guelph-Waterloo Centre for Chemistry and Biochemistry, Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.
Fabio E S
FE
Souza
Hamish S
HS
Sutherland
Rina
R
Carlini
Russell
R
Rodrigo