Role of dietary calcium and available phosphorus in the aetiology of tibial dyschondroplasia in growing turkeys.
1. Large White male turkeys from a heavy commercial male-line were fed 16 diets containing 4 concentrations of calcium (6, 10, 14 and 18 g/kg) and available phosphorus (3, 5, 7 and 9 g/kg) in a 4 x 4 factorial experiment. There were three replicates (pens) of each treatment and the skeletal health, morphology and mineral status of 4 turkeys from each pen were assessed at 7, 10 and 13 weeks of age. 2. The prevalence of tibial dyschondroplasia increased after 7 weeks of age and was present in 50 and 71% of turkeys respectively at 10 and 13 weeks. The lesion was localised in the caudal aspect of the proximal tibiae. Dietary calcium and available phosphorus did not affect the prevalence of the lesion except in turkeys on the diet containing 6 g calcium/kg, where body weight and the incidence of tibial dyschondroplasia were low. 3. Histological investigation showed no evidence of rachitic changes. 4. Low dietary calcium was associated with lower tibial plateau angles at 10 and 13 weeks of age. Tibial torsion and the angle of rotation were not affected by dietary treatments or age. Tibial torsion and the angle of rotation were not affected by dietary treatments or age. 5. Increasing dietary calcium increased tibial radiodensity, cortical density and the widths of the cortex and proximal tibiotarsus. Radiodensities increased to 10 weeks and were significantly lower at 13 weeks of age. 6. Bone ash, calcium and phosphorus declined with age, particularly between 10 and 13 weeks, whereas bone calcium: phosphorus ratios were not affected by dietary treatment or age. 7. Dietary calcium was positively associated with blood calcium and calcium ion concentrations and was without effect on blood phosphorus. Available phosphorus was associated positively with increased blood phosphorus and lower calcium ion concentrations but had no effect on total calcium. Alkaline phosphatase activity was low at high concentrations of dietary calcium with low available phosphorus and there was higher activity on diets containing low calcium and high available phosphorus.
Roslin Institute (Edinburgh), Roslin, Midlothian, Scotland. paul.hocking@bbsrc.ac.uk
P M
PM
Hocking
S
S
Wilson
L
L
Dick
L N
LN
Dunn
G W
GW
Robertson
C
C
Nixey
D000367:Age Factors; D000818:Animals; D015519:Bone Density; D002118:Calcium / Q000378:metabolism; D002136:Calcium, Dietary / Q000008:administration & dosage* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D008297:Male; D010009:Osteochondrodysplasias / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D010758:Phosphorus / Q000378:metabolism; D016226:Phosphorus, Dietary / Q000008:administration & dosage* / Q000378:metabolism; D011201:Poultry Diseases / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D015995:Prevalence; D013977:Tibia / Q000473:pathology; D014102:Torsion Abnormality; D014422:Turkeys
D002136:Calcium, Dietary; D016226:Phosphorus, Dietary; D010758:Phosphorus; D002118:Calcium