Kimura's disease: a diagnostic challenge.
Kimura's disease is a rare inflammatory disorder of unknown cause, primarily seen in young Asian males. The disease is characterized by a triad of painless subcutaneous masses in the head or neck region, blood and tissue eosinophilia, and markedly elevated serum immunoglobulin E levels. We describe an 11-year-old Asian boy with Kimura's disease who presented with a chronic left neck mass. The diagnosis was based on the characteristic histopathologic findings after surgical excision in conjunction with peripheral eosinophilia and elevated serum immunoglobulin E levels. Pediatricians in western countries should be aware of the clinical presentation of Kimura's disease.
Shetty
Avinash K
AK
Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA. avishetty@pol.net
Beaty
Michael W
MW
McGuirt
William F
WF
Woods
Charles R
CR
Givner
Laurence B
LB
D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D044466:Asian People; D001707:Biopsy, Needle; D002648:Child; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision; D008297:Male