Formins: taking a ride on the barbed end.
Formins are an ancient family of cell polarity regulators. Until recently, they were implicated in actin cytoskeleton regulation without a specific molecular function. That may all have changed with the publication of new results from several labs.
Deptartment of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge 02139, USA.
James E
JE
Bear
D008841:Actin Cytoskeleton / Q000378:metabolism* / Q000648:ultrastructure; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism; D016764:Cell Polarity / Q000502:physiology*; D005057:Eukaryotic Cells / Q000378:metabolism* / Q000648:ultrastructure; D005656:Fungal Proteins / Q000378:metabolism*; D006801:Humans; D008840:Microfilament Proteins; D008870:Microtubules / Q000378:metabolism* / Q000648:ultrastructure; D017434:Protein Structure, Tertiary / Q000502:physiology; D029701:Saccharomyces cerevisiae Proteins; D015003:Yeasts / Q000166:cytology / Q000378:metabolism
C105191:Bni1 protein, S cerevisiae; D002352:Carrier Proteins; D005656:Fungal Proteins; D008840:Microfilament Proteins; D029701:Saccharomyces cerevisiae Proteins