Synthesis of adenine from HCN tetramer and ammonium formate.
Adenine is formed in about 18% yield when HCN tetramer is heated with ammonium formate at 110 degrees C. The prebiotic significance of this reaction is discussed.
Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, San Diego, CA 92037-1099, USA.
Aubrey
A
Hill
Leslie E
LE
Orgel
D000225:Adenine / Q000138:chemical synthesis* / Q000737:chemistry*; D005561:Formates; D006856:Hydrogen Cyanide; D012996:Solutions
D005561:Formates; D012996:Solutions; C030544:formic acid; D006856:Hydrogen Cyanide; D000225:Adenine