[Treatment of severe viral hepatitis with artificial liver support system].
BACKGROUND
To investigate the method and therapeutic efficacy of artificial liver support system (ALSS) in treatment of severe viral hepatitis.


METHODS
A total of 83 patients including 66 with severe viral hepatitis were treated with ALSS using Baxter-550 artificial kidney and Biologic-DT system.


RESULTS
The levels of mean bilirubin, ALT, AST, BUN, Cr and endotoxin was significantly decreased after the treatment. Of the 66 patients?with severe viral hepatitis, 31(47.0%) had improvement in symptoms and 35 (53.0%) died or left hospital. In the control group,50(27.6%) out of the 181 had improvement in symptoms and 131(72.4%) died or left hospital.


CONCLUSIONS
ALSS could exert certain therapeutic effects on severe viral hepatitis.
The 302nd Hospital of PLA, Beijing, 100039, China.
Baosen
B
Li
Shaojie
S
Xin
Hanqian
H
Xing
Jun
J
Zhao
Zhengsheng
Z
Zou
Bin
B
Zhang
Deyong
D
Chen
Yuanli
Y
Mao
D000328:Adult; D005260:Female; D006525:Hepatitis, Viral, Human / Q000628:therapy*; D006801:Humans; D019164:Liver, Artificial; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome