[Hyperaldosteronism and simultaneous pheocromocytoma: a puzzle case].
Pheochromocytoma and primary hyperaldosteronism are well-known causes of hypertension. It was recently reported that their frequency in the hypertensive population is 0.1-0.2% and 3-15%, respectively. We describe the case study of a patient with severe hypertension (200/100 mmHg) and the coexistence of pheochromocytoma and primary hyperaldosteronism attributable to adrenal hyperplasia. The originality of this clinical report is that the patient presented a pheochromocytoma in the left adrenal gland and hyperplasia of the contralateral adrenal gland. The simultaneous presence of pheochromocytoma and primary hyperaldosteronism in the same patient is probably due to either genetic predisposition or to specific environmental risk factors for these adrenal diseases.
Centro di Fisiologia Clinica del CNR e Unita' Operativa di Nefrologia, Dialisi, Trapianto e Ipertensione, Reggio Calabria, Italy. mallamaci@area.cs.cnr.it
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D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery; D000311:Adrenal Glands / Q000378:metabolism / Q000473:pathology*; D002395:Catecholamines / Q000378:metabolism; D003404:Creatinine / Q000097:blood; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006965:Hyperplasia; D006973:Hypertension / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000378:metabolism; D010673:Pheochromocytoma / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery
D002395:Catecholamines; D003404:Creatinine