Potential applications of DNA microarrays in biodefense-related diagnostics.
Recent years have witnessed a logarithmic growth in the number of applications involving DNA microarrays. Extrapolation of their use for infectious diagnostics and biodefense-related diagnostics seems obvious. Nevertheless, the application of DNA microarrays to biodefense-related diagnostics will depend on solving a set of substantial, yet approachable, technical and logistical problems that encompass diverse topics from amplification efficiency to bioinformatics.
Stenger
David A
DA
Center for Bio/Molecular Science and Engineering, Code 6910, Naval Research Laboratory, Washington, DC 20375, USA. dstenger@ccs.nrl.navy.mil
Andreadis
Joanne D
JD
Vora
Gary J
GJ
Pancrazio
Joseph J
JJ
D023482:Bioterrorism; D004269:DNA, Bacterial / Q000145:classification* / Q000235:genetics; D004279:DNA, Viral / Q000145:classification* / Q000235:genetics; D004783:Environmental Microbiology; D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods; D020869:Gene Expression Profiling / Q000295:instrumentation; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis / Q000145:classification / Q000295:instrumentation* / Q000379:methods / Q000639:trends
D004269:DNA, Bacterial; D004279:DNA, Viral