Improved synthesis of 2,2'-bipyrimidine.
A high-yield synthesis was developed for the preparation of 2,2'-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4',6,6'-tetramethyl-2,2'-bipyrimidine (2) and 5,5'-dibromo-2,2'-bipyrimidine (3).
Department of Chemical Technology and Environmental Chemistry, Eötvös University, Pázmány Péter sétány 1/A, H-1117 Budapest, Hungary.
Gábor
G
Vlád
István T
IT
Horváth