Primary cerebral neuroblastoma: a case report and review.
Primitive neuroepithelial tumors are the least common among supratentorial tumors in children. They pose great diagnostic difficulty, preoperatively as well as pathologically. Being quite rare, cerebral neuroblastomas are accepted as a distinct pathological entity, which differs from other neuroectodermal tumors, although clinically, radiologically, and morphologically at operation they are indistinguishable. Also differentiation between primary cerebral neuroblastoma and the other primitive neuroectodermal tumors may be difficult on light microscopy and be misleading. A 9-year-old girl with primary cerebral neuroblastoma who was initially misdiagnosed is reported. The other cases from the literature are reviewed and the nature of this rare tumor and its differential diagnosis is discussed.
Kocaeli University Medical School, Department of Neurosurgery, Derince, Turkey. volkanetus@hotmail.com
Volkan
V
Etuş
Ozlem
O
Kurtkaya
Aydin
A
Sav
Konuralp
K
Ilbay
Savaş
S
Ceylan
D001707:Biopsy, Needle; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002648:Child; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D009447:Neuroblastoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy*; D018242:Neuroectodermal Tumors, Primitive / Q000000981:diagnostic imaging / Q000473:pathology*; D019635:Neurosurgical Procedures / Q000379:methods; D018714:Radiotherapy, Adjuvant; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome