IMGT, the international ImMunoGeneTics database: a high-quality information system for comparative immunogenetics and immunology.
IMGT, the international ImMunoGeneTics database (http://imgt.cines.fr), is a high quality integrated information system specializing in Immunoglobulins (IG), T cell Receptors (TR) and Major Histocompatibility Complex (MHC) of human and other vertebrates, created in 1989, by LIGM, at the Université Montpellier II, CNRS, Montpellier, France. IMGT provides a common access to standardized data, which include nucleotide and protein sequences, oligonucleotide primers, gene maps, genetic polymorphisms, specificities, 2D and 3D structures. IMGT includes several databases (IMGT/LIGM-DB, IMGT/HLA-DB, IMGT/3Dstructure-DB), Web resources ('IMGT Marie-Paule page') which comprise IMGT Scientific Chart, IMGT Repertoire, IMGT Bloc-notes, IMGT Education, IMGT Aide-mémoire and IMGT Index, and interactive tools (IMGT/V-QUEST, IMGT/JunctionAnalysis). These expertly annotated data on the genome, proteome, genetics and structure of the IG, TR and MHC are of high value for comparative genome evolution studies of the adaptative immune response.
Lefranc
Marie-Paule
MP
Laboratoire d'ImmunoGénétique Moléculaire, LIGM, Université Montpellier II, UPR CNRS 1142, IGH, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France. lefranc@ligm.igh.cnrs.fr
D000818:Animals; D001483:Base Sequence; D019295:Computational Biology; D017931:DNA Primers; D016208:Databases, Factual; D030562:Databases, Protein; D005602:France; D015723:Gene Library; D006801:Humans; D007125:Immunogenetics; D007136:Immunoglobulins / Q000737:chemistry / Q000235:genetics; D016247:Information Storage and Retrieval; D020407:Internet; D008285:Major Histocompatibility Complex / Q000235:genetics; D011110:Polymorphism, Genetic; D011948:Receptors, Antigen, T-Cell / Q000737:chemistry / Q000235:genetics
D017931:DNA Primers; D007136:Immunoglobulins; D011948:Receptors, Antigen, T-Cell