Secondary osteoporosis in women. A retrospective analysis.
Secondary osteoporosis comprises a minority of all osteoporosis cases. In this study we summarize the causes of secondary osteoporosis we encountered in patients currently on follow-up in our osteoporosis outpatient clinic. A total of 1015 female patients are involved in the study. Recorded data of the patients are evaluated retrospectively. Patients with spine bone mineral density (BMD) 2.5 standard deviation below a reference range established using our own data obtained from a Turkish population of normal healthy women using dual energy X-ray absorptiometry (T score less than -2.5) were accepted as having osteoporosis. We detected osteoporosis in 384 (38%) of the female patients. A secondary cause for osteoporosis has been found in 33 (8.6%) of the 384 osteoporotic patients. Thyrotoxicosis (n=10), parathyroid adenoma (n=10), and glucocorticoid administration (n=7) constituted 82% of the causes of osteoporosis. The data obtained in our study indicate that appropriate search for secondary causes of osteoporosis is essential because different modalities are needed for treatment.
Cakir
B
B
Department of Endocrinology, Gülhane School of Medicine, Etlik, Foça Sokak 90/28, Keçiören 06290 Ankara, Turkey. drcakir@yahoo.com
Odabasi
E
E
Turan
M
M
Güler
S
S
Kutlu
M
M
D015502:Absorptiometry, Photon; D000328:Adult; D015519:Bone Density; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications; D008499:Medical Records; D008875:Middle Aged; D010024:Osteoporosis / Q000139:chemically induced / Q000453:epidemiology* / Q000209:etiology*; D015663:Osteoporosis, Postmenopausal / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D013971:Thyrotoxicosis / Q000150:complications; D014421:Turkey / Q000453:epidemiology
D005938:Glucocorticoids