Light mediated cofactor recycling system in biocatalytic asymmetric reduction of ketone.
Reduction of an artificial ketone by Synechococcus elongatus PCC 7942 proceeds smoothly by the aid of light. The efficiency of the reaction is very high since the coenzyme NADPH is regenerated by using light energy.
Nakamura
Kaoru
K
Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan. nakamura@scl.kyoto-u.ac.jp
Yamanaka
Rio
R
D001711:Biotransformation; D002384:Catalysis; D000458:Cyanobacteria / Q000378:metabolism; D017743:Equipment Reuse; D006865:Hydrogenation; D007659:Ketones / Q000378:metabolism*; D008027:Light; D009249:NADP / Q000378:metabolism; D010788:Photosynthesis
D007659:Ketones; D009249:NADP