[Mitochondrial ion channels].
Ion channels selective for potassium or chloride ions are present in inner mitochondrial membranes. They are probably important in cellular events such as regulation of organelle volume changes. Additionally, mitochondrial potassium channels are targets for potassium channel openers and antidiabetic sulfonylureas. This review describes properties, and current hypotheses concerning the functional role of mitochondrial ion channels.
Pracownia Wewnatrzkomórkowych Kanałów Jonowych Instytutu Biologii Doświadczalnej im. M. Nenckiego PAN w Warszawie.
Grazyna
G
Debska
Anna
A
Kicińska
Jolanta
J
Skalska
Vladimir
V
Berest
Adam
A
Szewczyk
D000255:Adenosine Triphosphate / Q000378:metabolism; D018118:Chloride Channels / Q000378:metabolism; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism*; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism*; D015221:Potassium Channels / Q000378:metabolism; D013453:Sulfonylurea Compounds / Q000494:pharmacology; D013572:Synaptic Vesicles / Q000378:metabolism
D018118:Chloride Channels; D007473:Ion Channels; D015221:Potassium Channels; D013453:Sulfonylurea Compounds; D000255:Adenosine Triphosphate