Deformity correction of knee and leg lengthening by Ilizarov method in hypophosphatemic rickets: outcomes and significance of serum phosphate level.
The authors evaluated 14 patients with hypophosphatemic rickets who underwent correction of a knee deformity along with a leg lengthening by the Ilizarov method. Deformity correction alone was performed in 8 femora and 4 tibiae-fibulae, and concomitant deformity correction and limb lengthening (>1.0 cm) in 9 femora and 19 tibiae-fibulae. The healing index correlated with the biochemical parameters. Knee deformities were satisfactorily corrected in all patients except one. There was a statistically significant negative correlation between the healing index and the serum phosphate level: those who had a serum phosphate level higher than 2.5 mg/dL showed a relatively rapid regenerate bone healing compared with those with less than 2.5 mg/dL. The authors conclude that a serum phosphate level of 2.5 mg/dL as a cut-off point should be considered in deciding whether deformity correction alone or with a concomitant leg lengthening should be undertaken.
Department of Orthopaedic Surgery, Seoul National University Children's Hospital, Seoul, Korea. inhoc@snu.ac.kr
In Ho
IH
Choi
Jae Kwang
JK
Kim
Chin Youb
CY
Chung
Tae-Joon
TJ
Cho
Seok Hyun
SH
Lee
Seong Woo
SW
Suh
Kuhn Sung
KS
Whang
Hui Wan
HW
Park
Kwang Soon
KS
Song
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007015:Hypophosphatemia, Familial / Q000503:physiopathology / Q000601:surgery*; D018889:Ilizarov Technique; D016916:Joint Deformities, Acquired / Q000601:surgery*; D007719:Knee Joint; D008297:Male; D010710:Phosphates / Q000097:blood*
D010710:Phosphates