Preliminary in vivo experimental evidence on intratumoral morphine uptake. Possible clinical implications in cancer pain and opioid responsiveness.
Edoardo
E
Arcuri
Patrizia
P
Ginobbi
Walter
W
Tirelli
Rino
R
Froldi
Gennaro
G
Citro
Angela
A
Santoni
D000701:Analgesics, Opioid / Q000493:pharmacokinetics* / Q000627:therapeutic use; D004351:Drug Resistance; D005909:Glioblastoma / Q000378:metabolism*; D006801:Humans; D008545:Melanoma / Q000378:metabolism*; D009020:Morphine / Q000493:pharmacokinetics*; D009369:Neoplasms / Q000188:drug therapy / Q000503:physiopathology; D010146:Pain / Q000188:drug therapy / Q000503:physiopathology; D014407:Tumor Cells, Cultured
D000701:Analgesics, Opioid; D009020:Morphine