[Antimalarials in lupus erythematosus treatment].
Antimalarial therapy is regarded as the most successful treatment for cutaneous and also some symptoms of systemic lupus erythematosus. Although these drugs have been known for decades, the precise mechanisms of their action is not completely defined. Continuous research provides insight into the pathogenic mechanism of the antimalarial responsive disorders and facilitates the development of better targeted therapies. There are presented some relevant, putative and possible mechanisms by which antimalarials provide benefit in lupus patients.
Woźniacka
Anna
A
Katedra i Klinika Dermatologii i Wenerologii, Akademii Medycznej w Łodzi. wozniacka@bmp.net.pl
D000962:Antimalarials / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000188:drug therapy* / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy* / Q000473:pathology; D016032:Randomized Controlled Trials as Topic
D000962:Antimalarials