Pelvic haemophilic pseudotumour: management of a patient with high level of inhibitors.
Haemophilic pseudotumour (HP) is a rare but very serious complication of haemophilia. HP affects mainly patients with severe haemophilia and those who have developed antibodies to factor VIII or factor IX. We report on a 45-year-old man with haemophilia A and high titres of inhibitors who developed an extensive HP with progressive destruction of the right ilium over a period of 12 years. The different therapeutic options (conservative management by replacement therapy, surgical approach, radiotherapy, percutaneous evacuation with secondary refilled cavity and transcatheter arterial embolization) are reviewed.
Keller
A
A
Department of Radiology, Univesity Hospitals Geneva, Switzerland. Alain.Keller@hcuge.ch
Terrier
F
F
Schneider
P-A
PA
Bianchi
S
S
Howarth
N
N
De Moerloose
P
P
D001847:Bone Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D004621:Embolization, Therapeutic; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010388:Pelvis / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed