[Long-term changes after transplantation of expanded skin in dogs].
OBJECTIVE
To investigate the long-term changes of expanded skin after transplantation.


METHODS
The expanded skin in dogs at 0 week, 3 weeks, 6 weeks, 3 months and 6 months after transplantation was observed through areas, histomorphological, electron microscopic, collagen content, biomechanical, and immunohistochemical methods.


RESULTS
The expanded skin was close to the control groups in all observations.


CONCLUSIONS
The biological changes after expansion remain in 3 months. The expanded skin will gradually recover to normal in 3-6 months. It is similar to a wound repair process.
Plastic Surgery Hospital, CAMS and PUMC, Beijing 100041, China.
Huaxin
H
Hu
Guangci
G
Sun
Zhengwen
Z
Zhang
Xuejun
X
Liu
Haiming
H
Zhang
Zhifei
Z
Liu
D000818:Animals; D003094:Collagen / Q000032:analysis; D004285:Dogs; D005260:Female; D008297:Male; D012867:Skin / Q000737:chemistry / Q000648:ultrastructure; D016038:Skin Transplantation; D015626:Tissue Expansion
D003094:Collagen