[Familial transient red cell aplasia from parvovirus B-19 infection].
In our Paediatric Clinic we observed a case of transient aplastic crisis caused by Parvovirus B19 in a child and his mother, both affected by spherocytic haemolytic anemia. Anti-Parvovirus IgM antibody titre and viral search by PCR were positive. Anemia was treated with transfusion of concentrated red blood cells. In case of a family onset of hyperacute anemia it is necessary to consider a bone marrow aplastic crisis of the red series, induced by Parvovirus B19, especially if there is notice of an ongoing outbreak of erythema infectiosum.
Salvini
F
F
Clinica Pediatrica dell'Università di Milano, Ospedale San Paolo, Via A. di Rudinì, 8, 20142 Milano. clinped@mailserver.unimi.it
Tonella
M
M
Carpani
G
G
Scaglioni
S
S
Zuccotti
G V
GV
D000328:Adult; D000914:Antibodies, Viral / Q000276:immunology; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D007231:Infant, Newborn; D008297:Male; D010322:Parvoviridae Infections / Q000188:drug therapy / Q000276:immunology / Q000821:virology*; D016732:Parvovirus B19, Human / Q000276:immunology / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012010:Red-Cell Aplasia, Pure / Q000235:genetics* / Q000821:virology*; D013103:Spherocytosis, Hereditary / Q000235:genetics*
D000914:Antibodies, Viral; D007075:Immunoglobulin M