Toxic shock syndrome and streptococcal myositis: three case reports.
Group A streptococcal (GAS) infection is the most common cause of bacterial pharyngitis and has an important role in the pathogenesis of post-infective phenomena including rheumatic fever and glomerulonephritis. Mortality from GAS is uncommon, particularly in the paediatric population. Toxic shock syndrome reflects the most severe form of GAS-related disease and is often associated with fasciitis or myositis.


CONCLUSIONS
We present three cases of toxic shock syndrome secondary to (GAS) myositis demonstrating the importance of early recognition and provision of intensive care management.
Department of Child Health, University Hospital, Nottingham NG7 2UH, UK. ryanw@doctors.org.uk
Ryan
R
Watkins
Harish
H
Vyas
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D002981:Clindamycin / Q000627:therapeutic use; D003422:Critical Care; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D007223:Infant; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D009220:Myositis / Q000188:drug therapy / Q000382:microbiology*; D010406:Penicillins / Q000627:therapeutic use; D012772:Shock, Septic / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D013297:Streptococcus pyogenes
D000900:Anti-Bacterial Agents; D007136:Immunoglobulins; D010406:Penicillins; D008795:Metronidazole; D002981:Clindamycin