Pelvic haemophilic pseudotumour: management of a patient with high level of inhibitors.
Haemophilic pseudotumour (HP) is a rare but very serious complication of haemophilia. HP affects mainly patients with severe haemophilia and those who have developed antibodies to factor VIII or factor IX. We report on a 45-year-old man with haemophilia A and high titres of inhibitors who developed an extensive HP with progressive destruction of the right ilium over a period of 12 years. The different therapeutic options (conservative management by replacement therapy, surgical approach, radiotherapy, percutaneous evacuation with secondary refilled cavity and transcatheter arterial embolization) are reviewed.
Department of Radiology, Univesity Hospitals Geneva, Switzerland. Alain.Keller@hcuge.ch
A
A
Keller
F
F
Terrier
P-A
PA
Schneider
S
S
Bianchi
N
N
Howarth
P
P
De Moerloose
D001847:Bone Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D004621:Embolization, Therapeutic; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010388:Pelvis / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed