Total synthesis of epi-otteliones.
[reaction: see text] Syntheses of 6-epi- and 8-epi-otteliones, corresponding to earlier proposed structures of the biologically potent natural product ottelione A, have been accomplished from the readily available Diels-Alder adduct of cyclopentadiene and p-benzoquinone.
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India. gm@orgchem.iisc.ernet.in
Goverdhan
G
Mehta
Kabirul
K
Islam
D000970:Antineoplastic Agents / Q000138:chemical synthesis; D000995:Antitubercular Agents / Q000138:chemical synthesis; D018360:Crystallography, X-Ray; D003512:Cyclohexanones / Q000138:chemical synthesis* / Q000737:chemistry; D004987:Ethers; D031321:Hydrocharitaceae / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry
D000970:Antineoplastic Agents; D000995:Antitubercular Agents; D003512:Cyclohexanones; D004987:Ethers; C468748:ottelione A; C468747:ottelione B