Space-time clustering analyses of childhood acute lymphoblastic leukaemia by immunophenotype.
Space-time clustering analyses of acute lymphoblastic leukaemia in children, by immunophenotype, were carried out using a population-based registry. Significant evidence was found of space-time clustering for cases of the precursor B-cell sub-type, in the childhood peak, based on time and location at birth.
Cancer Research UK Paediatric & Familial Cancer Research Group, Stancliffe, Central Manchester and Manchester Children's University Hospitals NHS Trust, Hospital Road, Manchester M27 4HA, UK. richard.mcnally@man.ac.uk
R J Q
RJ
McNally
F E
FE
Alexander
J M
JM
Birch
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D015994:Incidence; D007223:Infant; D008297:Male; D014411:Neoplastic Stem Cells / Q000276:immunology; D011156:Population Density; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000453:epidemiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000145:classification / Q000453:epidemiology*; D012111:Residence Characteristics; D012189:Retrospective Studies; D012737:Sex Factors; D006113:United Kingdom / Q000453:epidemiology