A new cycloamphilectene metabolite from the Vanuatu sponge Axinella sp.
A new diterpene, N-formyl-7-amino-11-cycloamphilectene (1), was isolated from the apolar extract of the Vanuatu sponge Axinella sp. The structure and relative stereochemistry were established by spectroscopic and single-crystal X-ray studies.
Ciasullo
L
L
Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano (SA), Italy.
Cutignano
A
A
Casapullo
A
A
Puliti
R
R
Mattia
C A
CA
Debitus
C
C
Riccio
R
R
Gomez-Paloma
L
L
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*; D013237:Stereoisomerism; D009514:Vanuatu
D004224:Diterpenes; C466611:N-formyl-7-amino-11-cycloamphilectene