Intra-individual variability in urinary losartan oxidation ratio, an in vivo marker of CYP2C9 activity.
Yasar
Umit
U
Dahl
Marja-Liisa
ML
Christensen
Magnus
M
Eliasson
Erik
E
D000328:Adult; D000959:Antihypertensive Agents / Q000493:pharmacokinetics* / Q000652:urine; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics* / Q000378:metabolism; D015415:Biomarkers; D065729:Cytochrome P-450 CYP2C9; D005260:Female; D005838:Genotype; D006801:Humans; D019808:Losartan / Q000493:pharmacokinetics* / Q000652:urine; D008297:Male; D008875:Middle Aged
D000959:Antihypertensive Agents; D015415:Biomarkers; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; D019808:Losartan