Idiopathic multifocal intracardiac and pulmonary thrombosis: successful treatment with rTPA.
A 21-month-old boy with respiratory symptoms for one month secondary to idiopathic multichamber intracardiac and pulmonary thrombosis is presented who was successfully treated with recombinant tissue plasminogen activator (rTPA). The etiology and risk factors of pediatric intracardiac thrombosis are discussed and the literature and all reported cases are reviewed. It is important to consider cardiopulmonary thrombosis as a differential diagnosis of respiratory distress in childhood.
Department of Pediatric Cardiology, Royal Liverpool Children's NHS Trust, Alder Hey, Eaton Road, Liverpool, L12 2AP, United Kingdom. Holzer@doctors.org.uk
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R
Holzer
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Peart
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Ciotti
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PH
Bolton-Maggs
D003328:Coronary Thrombosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004452:Echocardiography; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator