Neonatal, severe primary hyperparathyroidism: a 7-year clinical and radiological follow-up of one patient.
Neonatal primary hyperparathyroidism is a rare entity characterized by marked hypercalcemia, diffuse parathyroid hyperplasia, and skeletal demineralization. It is often lethal unless total parathyroidectomy is performed. Long-term outcome of treated patients is poorly documented. We report the clinical and radiographic outcome of this disease in a 7-year-old boy who underwent a total parathyroidectomy and autotransplantation of a fragment of one parathyroid gland to his thigh in the neonatal period. This paper demonstrates the importance of prompt diagnosis and management in neonatal hyperparathyroidism and the role of various imaging modalities in its diagnosis and follow-up.
Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada. andrea.doria@sickkids.ca
Andrea S
AS
Doria
Carol
C
Huang
Outi
O
Makitie
Paul
P
Thorner
Sang W
SW
Kooh
Etienne
E
Sochett
Alan
A
Daneman
D003952:Diagnostic Imaging; D006801:Humans; D006961:Hyperparathyroidism / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D007231:Infant, Newborn; D008297:Male; D010280:Parathyroid Glands / Q000637:transplantation; D016105:Parathyroidectomy; D014182:Transplantation, Autologous