Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition?
Brasch
Robert C
RC
Center for Pharmaceutical and Molecular Imaging, Department of Radiology, University of California, San Francisco, USA.
Gossmann
Axel
A
Helbich
Thomas H
TH
Kuriyama
Nagato
N
Roberts
Timothy P L
TP
Shames
David M
DM
van Bruggen
N
N
Wendland
Michael F
MF
Israel
Mark A
MA
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D001932:Brain Neoplasms / Q000098:blood supply* / Q000473:pathology; D002199:Capillary Permeability; D003287:Contrast Media; D016228:Endothelial Growth Factors / Q000276:immunology; D005682:Gadolinium; D005910:Glioma / Q000098:blood supply* / Q000473:pathology; D036341:Intercellular Signaling Peptides and Proteins / Q000276:immunology; D008222:Lymphokines / Q000276:immunology; D008279:Magnetic Resonance Imaging; D008833:Microcirculation; D009389:Neovascularization, Pathologic / Q000473:pathology*; D051381:Rats; D011923:Rats, Nude; D014407:Tumor Cells, Cultured; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D000911:Antibodies, Monoclonal; D003287:Contrast Media; D016228:Endothelial Growth Factors; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D005682:Gadolinium