Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes.
Hair dye allergies are a frequent cause of occupational skin disease among hairdressers. Conventional hair dyes contain 4-phenylenediamine (PPD), 2, 5-diaminotoluene sulfate (DTS) and 2-nitro-4-phenylenediamine (ONPPD) as allergens. In new generation hair dyes, FD & C and D & C dyes are used in the hair dye formulations. This study investigated the cross-reaction pattern of new generation hair dyes among hairdressers (n = 40) with a known allergy to PPD and/or DTS and/or ONPPD. In the 40 hairdressers no positive reactions were observed to the single FD & C and D & C dyes. In two hairdressers, doubtful reactions were observed to one or more of the hair dye formulations. The data from this study suggest that for hairdressers sensitized to PPD and/or DTS and/or ONPPD this new generation of hair dyes is a safe alternative for use in their salons.
Fautz
Rolf
R
Goldwell Gmbh, Darmstadt, Germany.
Fuchs
Anne
A
van der Walle
Henk
H
Henny
Vida
V
Smits
Luuk
L
D000485:Allergens / Q000009:adverse effects; D016022:Case-Control Studies; D003429:Cross Reactions; D017449:Dermatitis, Allergic Contact / Q000209:etiology / Q000276:immunology*; D009783:Dermatitis, Occupational / Q000209:etiology / Q000276:immunology*; D006202:Hair Dyes / Q000009:adverse effects*; D006229:Hand Dermatoses / Q000139:chemically induced / Q000276:immunology*; D006801:Humans; D010328:Patch Tests; D010655:Phenylenediamines / Q000009:adverse effects
D000485:Allergens; D006202:Hair Dyes; D010655:Phenylenediamines; C007303:2,5-diaminotoluene; C014706:2-nitro-4-phenylenediamine; C029728:4-phenylenediamine