[Ischemic preconditioning decrease the release of cardiac troponin T during heart valve replacement].
Using cardiac troponin T(cTnT), a highly sensitive and specific marker of myocardial injury, we evaluated the effects of ischemic precondition on ischemic reperfusion myocardial injury. Thirty two patients were randomly divided into control group(n = 16) and ischemic preconditioning group(n = 16). The marker cTnT was measured in each group before operation, and 4 h, 24 h and 72 h after operation. The results showed that the peak value of cTnT was lower, and more quickly recovered in the preconditioning group than that in the control. It is suggested that ischemic preconditioning exert an evidently protective effect on ischemic reperfusion myocardial injury.
Jiang
H H
HH
Department of Thoracic and Cardiac Surgery, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Chen
S X
SX
Tang
Y
Y
D000328:Adult; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D019157:Ischemic Preconditioning, Myocardial; D008297:Male; D008944:Mitral Valve Insufficiency / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000601:surgery; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control*; D009206:Myocardium / Q000378:metabolism*; D012214:Rheumatic Heart Disease / Q000601:surgery; D020107:Troponin T / Q000378:metabolism*
D020107:Troponin T