ABCG4: a novel human white family ABC-transporter expressed in the brain and eye.
White family transporters are a group of ATP-binding cassette (ABC) proteins that show sequence homology to the Drosophila white gene product. The Drosophila protein is a subunit of heterodimeric transporters of precursors for eye-pigment synthesis. A novel, human member of this family (ABCG4) has been identified. Northern blotting shows that ABCG4 is expressed specifically in the brain and the eye.
Oldfield
Susan
S
University Research Centre for Neuroendocrinology, BRI, University of Bristol, Marlborough Street, Bristol BS2 8HW, UK. s.oldfield@bristol.ac.uk
Lowry
Christopher
C
Ruddick
Jon
J
Lightman
Stafford
S
D000070996:ATP Binding Cassette Transporter, Subfamily G; D018528:ATP-Binding Cassette Transporters / Q000096:biosynthesis* / Q000235:genetics; D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000378:metabolism*; D029721:Drosophila Proteins / Q000737:chemistry; D005123:Eye / Q000378:metabolism*; D005136:Eye Proteins / Q000737:chemistry; D015870:Gene Expression; D006801:Humans; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid
C439766:ABCG4 protein, human; D000070996:ATP Binding Cassette Transporter, Subfamily G; D018528:ATP-Binding Cassette Transporters; D029721:Drosophila Proteins; D005136:Eye Proteins; C059254:w protein, Drosophila