Anticipatory evolution and DNA shuffling.
DNA shuffling has proven to be a powerful technique for the directed evolution of proteins. A mix of theoretical and applied research has now provided insights into how recombination can be guided to more efficiently generate proteins and even organisms with altered functions.
Bacher
Jamie M
JM
Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.
Reiss
Brian D
BD
Ellington
Andrew D
AD
D004247:DNA / Q000235:genetics*; D019143:Evolution, Molecular; D011995:Recombination, Genetic / Q000235:genetics*
D004247:DNA