Clinical efficacy of an optimized stannous fluoride dentifrice, Part 4: A 3-month calculus clinical study, northwest USA.
The objective of this 3-month, double-blind study was to investigate the efficacy of Colgate Optimized Stannous Fluoride (COSF) dentifrice for the control of supragingival dental calculus accumulation. After 3 months' use, the COSF dentifrice group exhibited a statistically significant 56.6% reduction in supragingival calculus formation, as compared to the control dentifrice group. The results of this study support the conclusion that the COSF dentifrice is efficacious for controlling the accumulation of supragingival calculus.
Section of Radiology, University of the Pacific School of Dentistry, San Francisco, California, USA.
T
T
Schiff
J
J
Hadley
D M
DM
Petrone
M E
ME
Petrone
P
P
Chaknis
W
W
DeVizio
A R
AR
Volpe
H M
HM
Proskin
D000328:Adult; D000704:Analysis of Variance; D002626:Chemistry, Pharmaceutical; D002951:Citrates / Q000737:chemistry; D003728:Dental Calculus / Q000145:classification / Q000517:prevention & control*; D003802:Dentifrices / Q000737:chemistry / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012495:San Francisco; D012822:Silicon Dioxide / Q000737:chemistry; D012969:Sodium Fluoride / Q000627:therapeutic use; D017971:Tin Compounds / Q000737:chemistry; D014002:Tin Fluorides / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D014003:Tin Polyphosphates / Q000737:chemistry
D002951:Citrates; D003802:Dentifrices; D017971:Tin Compounds; D014002:Tin Fluorides; D014003:Tin Polyphosphates; C023599:stannous chloride; D012822:Silicon Dioxide; D012969:Sodium Fluoride