A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor.
Mikhailova
Ellina A
EA
Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Headington, Oxford, UK. michael.milchailov@ndcls.ox.ac.uk
Ashcroft
Stephen J H
SJ
Mikhailov
Michael V
MV
D018528:ATP-Binding Cassette Transporters; D000818:Animals; D002219:Carbamates / Q000378:metabolism; D005907:Gliclazide / Q000378:metabolism; D005905:Glyburide / Q000378:metabolism; D007004:Hypoglycemic Agents / Q000032:analysis* / Q000378:metabolism*; D007700:Kinetics; D010880:Piperidines / Q000378:metabolism; D015221:Potassium Channels / Q000378:metabolism*; D024661:Potassium Channels, Inwardly Rectifying; D011485:Protein Binding; D051381:Rats; D011955:Receptors, Drug / Q000378:metabolism*; D018411:Spodoptera / Q000378:metabolism; D064233:Sulfonylurea Receptors; D014044:Tolbutamide / Q000378:metabolism
D018528:ATP-Binding Cassette Transporters; D002219:Carbamates; D007004:Hypoglycemic Agents; D010880:Piperidines; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D011955:Receptors, Drug; D064233:Sulfonylurea Receptors; C072379:repaglinide; D014044:Tolbutamide; D005907:Gliclazide; D005905:Glyburide