[Post-partum autoimmune thyroiditis in a patient presenting with Sheehan's syndrome].
A 30-year-old women developed post-partum thyroiditis associated with post- partum pituitary infarction. Pituitary stimulation tests demonstrated global pituitary deficiency but there was no thyrotropin response to TRH stimulation and free T4 was normal. Associated goiter and high circulating levels of microsomal antibodies led to the diagnosis of post-partum thyroiditis associated with pituitary deficiency. Two cases of this unusual association have been reported. The underlying pathogenesis might involve post-partum immunological rebound and/or hypocorticism-induced immunological disorders.
Service d'Endocrinologie, Service de Physiologie et d'Explorations fonctionnelles, Tunisie, France.
B
B
Zantour
M
M
Chadli-Chaieb
A
A
Maaroufi
K
K
Ach
M
M
Zaouali-Ajina
Z
Z
Tabka
L
L
Chaieb
D000328:Adult; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D007987:Gonadotropin-Releasing Hormone; D006801:Humans; D007018:Hypopituitarism / Q000150:complications*; D007238:Infarction; D010902:Pituitary Gland / Q000098:blood supply; D011644:Puerperal Disorders; D013967:Thyroiditis, Autoimmune / Q000209:etiology* / Q000628:therapy; D013972:Thyrotropin / Q000378:metabolism; D013973:Thyrotropin-Releasing Hormone
D005938:Glucocorticoids; D007987:Gonadotropin-Releasing Hormone; D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin