[Plasmapheresis in combine therapy of hypercoagulation syndrome in hematogenic thrombophilia].
OBJECTIVE
To specify indications to plasmapheresis (PA) and to assess its efficiency in patients with hypercoagulatory syndrome in hematogenic thrombophilia (HT).


METHODS
18 patients (11 males, 7 females, age 26-50 years) with various forms of HT received standard antiaggregation, anticoagulatory therapy plus therapeutic PA. By PA technique the patients were divided into two groups.


RESULTS
A positive trend in clinical, instrumental and laboratory indices was observed in all the patients.


CONCLUSIONS
Therapeutic PA in hypercoagulation syndrome in HT patients leads to fast normalization of the clinical picture and reestablishment of patency of thrombus-affected vessels.
Vasil'ev
S A
SA
Gorodetskiĭ
V M
VM
Kalinin
N N
NN
Berkovskiĭ
A L
AL
Petrova
V I
VI
Rudakova
V E
VE
Orel
E B
EB
Sergeeva
E V
EV
Kravchenko
S K
SK
Margolin
O V
OV
Efremov
E E
EE
Shevelev
A A
AA
Tsvetaeva
N V
NV
Avdonin
P V
PV
Vorob'ev
A I
AI
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D019851:Thrombophilia / Q000188:drug therapy / Q000628:therapy*
D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors