Secondary osteoporosis in women. A retrospective analysis.
Secondary osteoporosis comprises a minority of all osteoporosis cases. In this study we summarize the causes of secondary osteoporosis we encountered in patients currently on follow-up in our osteoporosis outpatient clinic. A total of 1015 female patients are involved in the study. Recorded data of the patients are evaluated retrospectively. Patients with spine bone mineral density (BMD) 2.5 standard deviation below a reference range established using our own data obtained from a Turkish population of normal healthy women using dual energy X-ray absorptiometry (T score less than -2.5) were accepted as having osteoporosis. We detected osteoporosis in 384 (38%) of the female patients. A secondary cause for osteoporosis has been found in 33 (8.6%) of the 384 osteoporotic patients. Thyrotoxicosis (n=10), parathyroid adenoma (n=10), and glucocorticoid administration (n=7) constituted 82% of the causes of osteoporosis. The data obtained in our study indicate that appropriate search for secondary causes of osteoporosis is essential because different modalities are needed for treatment.
Department of Endocrinology, Gülhane School of Medicine, Etlik, Foça Sokak 90/28, Keçiören 06290 Ankara, Turkey. drcakir@yahoo.com
B
B
Cakir
E
E
Odabasi
M
M
Turan
S
S
Güler
M
M
Kutlu
D015502:Absorptiometry, Photon; D000328:Adult; D015519:Bone Density; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications; D008499:Medical Records; D008875:Middle Aged; D010024:Osteoporosis / Q000139:chemically induced / Q000453:epidemiology* / Q000209:etiology*; D015663:Osteoporosis, Postmenopausal / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D013971:Thyrotoxicosis / Q000150:complications; D014421:Turkey / Q000453:epidemiology
D005938:Glucocorticoids