Bone mineral density in adolescent and young Thai girls receiving oral contraceptives compared with depot medroxyprogesterone acetate: a cross-sectional study in young Thai women.
This cross-sectional study of bone mineral density in adolescent and young Thai girls receiving oral contraceptives compared with depot medroxyprogesterone acetate was performed to evaluate the differences among these groups. Thirty current OC users and 30 current depot medroxyprogesterone acetate (DMPA) users were included in the study. The mean duration of OC use was 28.8 +/- 3.4 months and of DMPA 24.6 +/- 3.3 months. Dual energy X-ray absorptiometry (DEXA) was used to measure bone mineral density (BMD) at distal and ultradistal forearm of the nondominant side. The BMD of ultradistal forearm of OC users and that of DMPA users were 0.423 +/- 0.048 and 0.403 +/- 0.039 g/cm(2) and at distal forearm of OC and DMPA users were 0.566 +/- 0.043 and 0.571 +/- 0.064 g/cm(2), respectively. However, there were no statistical differences in BMD in these two groups.
Department of Obstetrics and Gynaecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wanwi707@hotmail.com
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Taneepanichskul
D015502:Absorptiometry, Photon; D000293:Adolescent; D000328:Adult; D015519:Bone Density / Q000187:drug effects*; D003276:Contraceptives, Oral / Q000008:administration & dosage*; D003430:Cross-Sectional Studies; D003692:Delayed-Action Preparations; D005260:Female; D005542:Forearm; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage*; D013785:Thailand
D003276:Contraceptives, Oral; D003692:Delayed-Action Preparations; D017258:Medroxyprogesterone Acetate