[The other face of statins].
Clinical studies indicate that treatment with statins significantly reduces the incidence of myocardial infarction and death from cardiovascular diseases. Quite recently statins were found to exert a direct cardiovascular effect, which is independent on their well-known cholesterol lowering action. In this article current views on the role of statins in improvement of function of vascular endothelium are presented.
Kaletha
Krystian
K
Katedra i Zakład Biochemii Akademii Medycznej w Gdańsku.
Chodorowski
Zygmunt
Z
Sein Anand
Jacek
J
Szydłowska
Magdalena
M
Rybakowska
Iwona
I
Nagel-Starczynowska
Gabriela
G
D000924:Anticholesteremic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology; D004730:Endothelium, Vascular / Q000187:drug effects; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000188:drug therapy*; D019821:Simvastatin / Q000494:pharmacology* / Q000627:therapeutic use*
D000924:Anticholesteremic Agents; D019821:Simvastatin