Relative efficacy of DEPA and neem oil for repellent activity against Phlebotomus papatasi, the vector of leishmaniasis.
The insect repellent N, N-diethylphenyl acetamide (DEPA) was compared with neem oil, a commercial preparation, for protection against 3 day old un-fed female of the sandfly, Phlebotomus papatasi, (Diptera: Psychodidae) under laboratory conditions on mouse. The percentage protection against sandfly bite provided by neem oil was significantly higher than DEPA when applied at 1% and 2% concentrations (p = 0.000, t = 21.474; df = 6 and p = 0.001, t = 5.960; df = 6 respectively). However, neem oil did not show any significant difference with DEPA at 5% (p = 0.1682, t = 0.15667; df = 6). This clearly indicates that at higher concentration (5%) both neem oil and DEPA exhibited similar repellent action against P. papatasi.
Srinivasan
R
R
Vector Control Research Centre, Pondicherry-605 006, India.
Kalyanasundaram
M
M
D000081:Acetamides / Q000494:pharmacology*; D000083:Acetanilides; D000818:Animals; D005260:Female; D005989:Glycerides / Q000494:pharmacology*; D007302:Insect Repellents / Q000494:pharmacology*; D007303:Insect Vectors / Q000187:drug effects* / Q000502:physiology; D007896:Leishmaniasis / Q000469:parasitology / Q000517:prevention & control*; D008297:Male; D051379:Mice; D010691:Phlebotomus / Q000187:drug effects* / Q000502:physiology*; D013729:Terpenes / Q000494:pharmacology*
D000081:Acetamides; D000083:Acetanilides; D005989:Glycerides; D007302:Insect Repellents; D013729:Terpenes; C002443:neem oil; C044250:N,N-diethylphenylacetamide