Synthesis of cyclophanetetrayne complexes from bis(propargyldicobalt) dication equivalents.
Nicholas reactions of the p-phenyl linked bis(propargyl acetate) complex (3a) with electron rich arenes give cyclophanetetrayne complexes (5). The use of bis(propargyl ether) complex (8) with (3a) allows formation of a mixed cyclophanetetrayne complex (9), and in addition gives retro-Nicholas/intramolecular Nicholas reaction product (2).
Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada.
Romelo
R
Gibe
James R
JR
Green
D000840:Anisoles / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007202:Indicators and Reagents; D010293:Pargyline / Q000138:chemical synthesis*
D000840:Anisoles; D000970:Antineoplastic Agents; D007202:Indicators and Reagents; D010293:Pargyline; C091694:1,2,3-trimethoxybenzene