Extensive Riga-Fede disease of the lip and tongue.
Riga-Fede disease presents in early infancy and is characterized by firm, verrucous plaques arising on the oral mucosal surfaces. These histologically benign lesions occur as a result of repetitive trauma of the oral mucosal surfaces by the teeth. Early recognition of this entity is important, because it may be the presenting sign of an underlying neurologic disorder. We report the case of a 10-month-old boy with extensive Riga-Fede disease involving the lip and tongue that prompted a diagnosis of congenital autonomic dysfunction with universal pain loss.
Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York 10016, USA.
Andrea L
AL
Zaenglein
Mary Wu
MW
Chang
Shane A
SA
Meehan
Felicia B
FB
Axelrod
Seth J
SJ
Orlow
D001342:Autonomic Nervous System Diseases / Q000150:complications; D006801:Humans; D007223:Infant; D008046:Lip / Q000293:injuries*; D008297:Male; D019226:Oral Ulcer / Q000209:etiology*; D000699:Pain Insensitivity, Congenital / Q000150:complications*; D014059:Tongue / Q000293:injuries*; D014070:Tooth