[Isolation, biological properties, and spatial structure of an antibiotic loloatin A].
Peptide antibiotic with cyanolytic activity was isolated from the IGM52 strain of the Brevibacillus laterosporus Gram-positive spore-forming bacteria. By 1H NMR spectroscopy, this antibiotic was identified as loloatin A, a cyclic decapeptide cyclo(-Asn-Asp-Tyr-Val-Orn-Leu-DTyr-Pro-Phe-DPhe-). The spatial structure of loloatin A in solution was determined. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2002, vol. 28, no. 4; see also http://www.maik.ru.
Krachkovskiĭ
S A
SA
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia.
Sobol'
A G
AG
Ovchinnikova
T V
TV
Tagaev
A A
AA
Iakimenko
Z A
ZA
Azizbekian
R R
RR
Kuznetsova
N I
NI
Shamshina
T N
TN
Arsen'ev
A S
AS
D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001407:Bacillus / Q000737:chemistry*; D000458:Cyanobacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011487:Protein Conformation
D000900:Anti-Bacterial Agents; D010456:Peptides, Cyclic