[Split-liver transplantation in two adult recipients: evaluation of feasibility in 100 consecutive cadaver liver grafts].
OBJECTIVE
To evaluate the feasibility of splitting a liver graft for transplantation in two adult patients.


METHODS
We retrospectively collected data on the harvesting of 100 consecutive liver grafts. Data were separated into 4 groups to establish feasibility criteria, according to the chronological steps of harvesting: 1) initial criteria about the donor (age, weight, biological tests), 2) criteria concerning the liver graft at the time of harvesting (macroscopic appearance, graft weight, hemodynamic state of donor), (3) anatomical criteria and (4) histological criteria.


RESULTS
If our criteria for the feasibility of splitting a liver graft for transplantation in two adults had been applied, 47 grafts would have been rejected based on initial criteria, 34 at the time of harvesting and 6 because of anatomical or histological evaluation. Finally, 13 liver grafts would have been accepted for splitting and then transplantation in two adults.


CONCLUSIONS
Split-liver transplantation for two adult recipients could increase the graft pool by 13%. This procedure requires technical changes in organ harvesting and coordination among centers.
Poncet
Gilles
G
Unité de Transplantation Hépatique, Fédération des Spécialités Digestives, Hôpital Edouard Herriot, Lyon, France.
Dumortier
Jérôme
J
Choucair
Antoine
A
Dawahra
Marwan
M
Boucaud
Catherine
C
Scoazec
Jean-Yves
JY
Boillot
Olivier
O
D000293:Adolescent; D000328:Adult; D001835:Body Weight; D002102:Cadaver; D002648:Child; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008099:Liver / Q000033:anatomy & histology; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014019:Tissue Donors