Go and chemoresistance of malignant cells.
In general terms the paper discusses the relevance of mitotically quiescent, malignant cells for increasing resistance to chemotherapy. Detailed are some routes to Go for malignancies either dependent or autonomous for their mitotic potential.
Matioli
G T
GT
USC Medical School, 2011 Zonal Avenue, Los Angeles, CA, USA.
D019008:Drug Resistance, Neoplasm; D006801:Humans; D009369:Neoplasms / Q000473:pathology*; D016192:Resting Phase, Cell Cycle