Platelet glycoprotein IIb/IIIa receptor blockade with integrilin (eptifibatide) for early postinfarction angina in a patient with coronary arterial ectasia.
A middle-aged male with multivessel proximal coronary ectasia presented with thrombosis-related acute myocardial infarction and early postinfarct angina, and was successfully treated with a combination of intravenous integrilin (eptifibatide) and unfractionated heparin. The possible aetiology, prognosis and available management strategies are discussed.
Helen Joseph Hospital, Department of Cardiology, University of the Witwatersrand, Johannesburg, South Africa.
V
V
Grigorov
L
L
Goldberg
J
J
Mekel
D000328:Adult; D000789:Angina, Unstable / Q000188:drug therapy* / Q000209:etiology; D000925:Anticoagulants / Q000627:therapeutic use*; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000187:drug effects; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging / Q000188:drug therapy; D004359:Drug Therapy, Combination; D000077542:Eptifibatide; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D017202:Myocardial Ischemia / Q000150:complications / Q000188:drug therapy; D010455:Peptides / Q000627:therapeutic use*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*
D000925:Anticoagulants; D010455:Peptides; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D006493:Heparin; D000077542:Eptifibatide