Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase.
Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Michael L
ML
Mitchell
Feng
F
Tian
Lac V
LV
Lee
Chi-Huey
CH
Wong
D002614:Chelating Agents; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D005643:Fucose / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D005647:Fucosyltransferases / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D002614:Chelating Agents; D004791:Enzyme Inhibitors; D013844:Thiazoles; D005643:Fucose; D005647:Fucosyltransferases; C031692:galactoside 3-fucosyltransferase