Labor and cost requirements of two commercial assays for qualitative molecular detection of hepatitis C virus.
The Bayer transcription-mediated amplification (TMA) and the Roche PCR Amplicor version 2.0 molecular assays for the qualitative detection of hepatitis C virus were compared for cost, hands-on time, assay duration, and complexity. The TMA assay compares well to PCR and may be especially useful for laboratories with large numbers of test requests.
Schrijver
Iris
I
Department of Pathology, Stanford University School of Medicine, California, USA.
Baron
Ellen Jo
EJ
D003365:Costs and Cost Analysis; D006280:Health Workforce; D016174:Hepacivirus / Q000302:isolation & purification* / Q000502:physiology; D006526:Hepatitis C / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D021141:Nucleic Acid Amplification Techniques / Q000191:economics* / Q000379:methods; D016133:Polymerase Chain Reaction / Q000191:economics; D012367:RNA, Viral / Q000032:analysis*; D011933:Reagent Kits, Diagnostic / Q000191:economics*; D013997:Time Factors; D014158:Transcription, Genetic; D019562:Viral Load
D012367:RNA, Viral; D011933:Reagent Kits, Diagnostic