Congenital Spitz nevus clinically mimicking melanoma.
The differentiation between atypical variants of Spitz nevus and melanoma is often difficult given the many clinical and histopathologic similarities between the two. We report a case of an infant with a congenital scalp lesion exhibiting clinical features of melanoma, including variegation and regression of pigmentation and a rapidly changing appearance. Histologic examination of the excised lesion revealed a benign congenital Spitz nevus. This case emphasizes the need for clinical and histologic correlation in determining the benign or malignant nature of atypical pigmented lesions in infants.
Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York 10016, USA.
Andrea L
AL
Zaenglein
Patrick
P
Heintz
Hideko
H
Kamino
Martin
M
Zisblatt
Seth J
SJ
Orlow
D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000151:congenital* / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008545:Melanoma / Q000473:pathology*; D018332:Nevus, Epithelioid and Spindle Cell / Q000151:congenital* / Q000473:pathology*; D012535:Scalp; D012878:Skin Neoplasms / Q000151:congenital* / Q000473:pathology*