Co-occurrence of psoriatic arthritis with collagenous colitis: clinicopathologic findings of a case.
A 58-year-old man developed psoriatic arthritis and, after 6 months, persistent watery diarrhoea. Biopsies from the colorectal mucosa showed thickened subepithelial collagen consistent with collagenous colitis. There also was an inflammatory cell infiltration (mainly lymphocytes and monocytes) in the chorion. These findings and the parallel course of articular and bowel complaints suggest a clinicopathologic correlation between arthritis and colic involvement.
Dipartimento di Terapia Medica, University La Sapienza, Policlinico Umberto, Rome, Italy.
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E
Taccari
S
S
Spada
A
A
Giuliani
V
V
Riccieri
M L
ML
Sorgi
I
I
Pecorella
A
A
Onetti Muda
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D015535:Arthritis, Psoriatic / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D001175:Arthrography; D003092:Colitis / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D003094:Collagen / Q000378:metabolism*; D004359:Drug Therapy, Combination; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism / Q000648:ultrastructure; D007596:Joints / Q000473:pathology; D007660:Ketoprofen / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008854:Microscopy, Electron; D008875:Middle Aged; D012460:Sulfasalazine / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D012460:Sulfasalazine; D003094:Collagen; D007660:Ketoprofen; D008775:Methylprednisolone