[Reproducibility of measurements with the retinal vessel analyzer under optimal conditions].
BACKGROUND
[corrected] To evaluate the reproducibility of measurements with the Retinal Vessel Analyzer (RVA) in healthy subjects and to describe which measuring conditions should be guaranteed to obtain optimal results.


METHODS
The diameter of retinal arteries and veins of 20 healthy subjects (M : F = 11 : 9; mean age: 33 +/- 12 years) were measured with the RVA at baseline, after 2 hours, and after 2 weeks.


RESULTS
No statistically significant differences in the diameter of retinal arteries and veins between the single measurements were present. Short-term variability of arterial diameter was 1 %, and the intraclass correlation coefficient kappa was 0.96. Long-term variability was 1.8 %, kappa was 0.98. In retinal veins, a short-term variability of 1 % was calculated, with a kappa of 0.97. Long-term variability was 1.5 %, with a kappa of 0.98.


CONCLUSIONS
Due to the high reproducibility of its measurements, the RVA appears to be a useful device for both analysis and follow-up of retinal vessel diameters.
Pache
Mona
M
Universitäts-Augenklinik Basel, Germany.
Nagel
Edgar
E
Flammer
Josef
J
D000328:Adult; D005260:Female; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008297:Male; D009862:Online Systems; D019721:Ophthalmoscopes; D010100:Oxygen / Q000097:blood; D012016:Reference Values; D012161:Retinal Artery / Q000033:anatomy & histology*; D012169:Retinal Vein / Q000033:anatomy & histology*
D010100:Oxygen