Flow-induced wall shear stress in abdominal aortic aneurysms: Part I--steady flow hemodynamics.
Numerical predictions of blood flow patterns and hemodynamic stresses in Abdominal Aortic Aneurysms (AAAs) are performed in a two-aneurysm, axisymmetric, rigid wall model using the spectral element method. Homogeneous, Newtonian blood flow is simulated under steady conditions for the range of Reynolds numbers 10 < or =Re < or =2265. Flow hemodynamics are quantified by calculating the distributions of wall pressure (p(w)), wall shear stress (tau(w)), Wall Shear Stress Gradient (WSSG). A correlation between maximum values of hemodynamic stresses and Reynolds number is established, and the spatial distribution of WSSG is considered as a hemodynamic force that may cause damage to the arterial wall at an intermediate stage of AAA growth. The temporal distribution of hemodynamic stresses in pulsatile flow and their physical implications in AAA rupture are discussed in Part II of this paper.
Mechanical Engineering, Biomedical and Health Engineering, and institute for Complex Engineered Systems, Carnegie Mellon University, Pittsburgh, PA, USA.
Ender A
EA
Finol
Cristina H
CH
Amon
D001012:Aorta, Abdominal / Q000503:physiopathology*; D017544:Aortic Aneurysm, Abdominal / Q000503:physiopathology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D003198:Computer Simulation; D004548:Elasticity; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D013314:Stress, Mechanical