Adult onset Still's disease as a cause of ARDS and acute respiratory failure.
We report a case of a young woman with pyrexia and progressive lung disease who developed acute respiratory distress syndrome (ARDS) and required prolonged mechanical ventilator support. The patient had a markedly elevated serum ferritin concentration of 7880 micrograms/L, a specific finding for the adult onset Still's disease (AOSD). Treatment of the patient with supportive and immunosuppressive therapy, resulted in patient survival and cure. The early consideration of the diagnosis of AOSD in patients with fever of unknown origin and a compatible clinical course may modify its severe complications.
Suleiman
Mahmoud
M
Department of Internal Medicine D, Rambam Medical Center, P.O. Box 9602, Haifa 31096, Israel.
Wolfovitz
Efrat
E
Boulman
Nina
N
Levy
Yishai
Y
D000208:Acute Disease; D000328:Adult; D005260:Female; D006801:Humans; D012128:Respiratory Distress Syndrome / Q000209:etiology*; D012131:Respiratory Insufficiency / Q000209:etiology*; D016706:Still's Disease, Adult-Onset / Q000150:complications* / Q000175:diagnosis