Developmental expression of a class IV POU gene in the gastropod Haliotis asinina supports a conserved role in sensory cell development in bilaterians.
POU-IV genes regulate neuronal development in a number of deuterostomes (chordates) and ecdysozoans (arthropods and nematodes). Currently their function and expression in the third bilaterian clade, the Lophotrochozoa, comprising molluscs, annelids and their affiliates, is unclear. Herein we characterise the developmental expression of HasPOU-IV in the gastropod mollusc, Haliotis asinina. The POU-IV gene is transiently expressed in 11 distinct larval territories during the first 3 days of development. HasPOU-IV is first expressed in sets of ventral epidermal cells in the newly hatched trochophore larvae. As larval morphogenesis proceeds, we observe HasPOU-IV transcripts in cells that putatively form a range of sensory systems including chemo- and mechanosensory cells in the foot, cephalic tentacles, the ctenidia, the geosensory statocyst and the eyes. By comparing HasPOU-IV expression with POU-IV genes in other bilaterians we infer that this class of POU-domain genes had an ancestral role in regulating sensory cell development.
O'Brien
Elizabeth K
EK
Department of Zoology and Entomology, University of Queensland, Brisbane, Queensland 4072, Australia.
Degnan
Bernard M
BM
D000818:Animals; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox / Q000502:physiology*; D007814:Larva / Q000235:genetics / Q000254:growth & development; D008974:Mollusca / Q000254:growth & development* / Q000378:metabolism; D005810:Multigene Family; D012679:Sense Organs / Q000254:growth & development*; D014157:Transcription Factors / Q000096:biosynthesis* / Q000235:genetics
D014157:Transcription Factors