[Smoking in pregnancy--long term effect].
OBJECTIVE
The data review on the cancer risk in children exposed to tobacco smoke in utero.


METHODS
The analysis was based on databases available in Medline, Cancerlit and Cochrane.


RESULTS
The reviewed data confirm that the risk of developing malignancy after the exposure to maternal smoking is low. Nevertheless, some publications point to a higher risk of having brain tumors or leukemias.


CONCLUSIONS
Together with facts that fetus is jeopardized with toxic metabolites of tobacco smoke which cause genotoxic effects or DNA adducts give additional arguments the necessity of introducing smoking cessation programs in perinatal care.
Sipowicz
Marek A
MA
Zakładu Patofizjologii Ciazy Akademii Medycznej w Białymstoku.
Laudański
Tadeusz
T
D001932:Brain Neoplasms / Q000209:etiology; D002648:Child; D005260:Female; D006801:Humans; D007938:Leukemia / Q000209:etiology; D008223:Lymphoma / Q000209:etiology; D008425:Maternal Behavior; D008431:Maternal-Fetal Exchange; D009369:Neoplasms / Q000209:etiology*; D010353:Patient Education as Topic; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012306:Risk; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation