[Chronic respiratory disease and gastroesophageal reflux].
Both GERD(gastroesophageal reflux disease) and chronic respiratory disease are common disease in old and the association between GERD and chronic respiratory disease are recently proved in many reports. Patient with GERD have a higher prevalence of asthma and chronic cough. Aggressive antireflux therapy in patient with asthma and GERD results in improvement in asthma outcome. In our study, endoscopic examination revealed that the prevalence of esophageal mucosal disease in patient with asthma was about 83%. In this paper, I review the role of GERD in chronic respiratory disease, especially asthma.
Dobashi
Kunio
K
First Department of Internal Medicine, Faculty of Medicine, School of Medicine, Gunma University.
D001249:Asthma / Q000209:etiology; D002908:Chronic Disease; D003371:Cough / Q000209:etiology; D004035:Diet Therapy; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000628:therapy; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D009853:Omeprazole / Q000627:therapeutic use; D011015:Pneumonia, Aspiration / Q000150:complications; D054328:Proton Pump Inhibitors; D012018:Reflex; D012140:Respiratory Tract Diseases / Q000209:etiology*; D014630:Vagus Nerve / Q000503:physiopathology
D006635:Histamine H2 Antagonists; D054328:Proton Pump Inhibitors; D009853:Omeprazole