Intramucosal naevus with pseudoepitheliomatous hyperplasia in the gingiva: a case report.
This article describes the unusual case of an intraoral pigmented naevus with pseudoepitheliomatous hyperplasia of the gingiva. A 62-year-old man presented with an almost coal-black pigmented and partly white, spotted, dome-shaped swelling on the lingual gingiva of the mandible. Histologically, the lesion consisted of clusters of round-shaped naevus cells containing melanin granules, reactive with both S-100 immunohistochemical stain and Masson-Fontana silver stain, and pseudoinvasive squamous nests, reactive with cytokeratin. The pathogenesis of the present lesion and problems encountered in its differential diagnosis are discussed.
Department of Oro-Maxillofacial Surgical Science, Tohoku University Graduate School of Dentistry, Sendai, Japan. takahiro@mail.cc.tohoku.ac.jp
T
T
Suzuki
H
H
Kumamoto
H
H
Nagasaka
H
H
Kawamura
K
K
Ooya
D002280:Basal Cell Carcinoma / Q000175:diagnosis; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003937:Diagnosis, Differential; D005885:Gingival Hyperplasia / Q000175:diagnosis / Q000209:etiology; D005887:Gingival Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008334:Mandible; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009508:Nevus, Pigmented / Q000150:complications / Q000473:pathology*