Pyrethroid exposure of the general population-is this due to diet.
Inhabitants (1177) of a residential area in Frankfurt/Main have been investigated with respect to internal exposure to pyrethroids. Biological monitoring revealed a body burden of pyrethroids. The 95th per thousand for the urinary metabolites of pyrethroids, such as permethrin and cypermethrin, cis and trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (cis-DCCA and trans-DCCA), was determined to be 0.5 and 1.4 microg/l, respectively. 95th per thousand for cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA), a specific metabolite of deltamethrin, and 4-fluoro-3-phenoxybenzoic acid (F-PBA), a metabolite of cyfluthrin, were 0.3 and 0.27 microg/l, respectively. The metabolic pattern found for these samples points out that pyrethroids are probably ingested orally with daily diet.
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-University of Erlangen-Nürnberg, Schillerstrasse 25/29, D-91054, Erlangen, Germany.
Thomas
T
Schettgen
Ursel
U
Heudorf
Hans
H
Drexler
Jürgen
J
Angerer
D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004032:Diet; D004781:Environmental Exposure / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods*; D005260:Female; D005858:Germany; D006801:Humans; D007223:Infant; D007306:Insecticides / Q000493:pharmacokinetics* / Q000652:urine; D008297:Male; D008875:Middle Aged; D011722:Pyrethrins / Q000493:pharmacokinetics* / Q000652:urine
D015415:Biomarkers; D007306:Insecticides; D011722:Pyrethrins