Association of plasma viral RNA load with prognosis in cats naturally infected with feline immunodeficiency virus.
We measured the quantity of plasma feline immunodeficiency virus (FIV) RNA using a real-time sequence detecting system. Plasma viral RNA load was shown to correlate with the clinical stage, survival time, and disease progression in naturally FIV-infected cats. The present study indicates that the plasma viral RNA load can be used as a clinical marker representing the impairment of the immune system and predicting the clinical outcome in FIV-infected cats.
Goto
Yuko
Y
Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Nishimura
Yoshiaki
Y
Baba
Kenji
K
Mizuno
Takuya
T
Endo
Yasuyuki
Y
Masuda
Kenichi
K
Ohno
Koichi
K
Tsujimoto
Hajime
H
D000818:Animals; D018791:CD4 Lymphocyte Count; D002415:Cats; D016181:Feline Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000401:mortality / Q000821:virology*; D011379:Prognosis; D012367:RNA, Viral / Q000097:blood*; D019562:Viral Load
D012367:RNA, Viral