Differentiation of hydatid cyst from cysticercus cyst by proton MR spectroscopy.
The metabolite patterns obtained by ex vivo proton MR spectroscopy of fluid from different locations of hydatid cysts of sheep and humans (n = 16) and cysticercus cysts of swine and humans (n = 25) were compared with an objective of differentiating the two parasites on the basis of their metabolite pattern. The spectra from hydatid fluid differed from cysticercus cyst by the absence of creatine in the former. When the hydatid cyst was fertile, malate and/or fumarate was also observed, which was absent in cysticercus cyst. The most likely explanation for the presence of creatine only in the cysticercus fluid is its active diffusion from the surrounding host tissue along with a contribution from the musculature present in the bladder wall of the cyst.
Garg
Monika
M
Department of Radiology, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Lucknow, India.
Chawla
Sanjeev
S
Prasad
Kashi N
KN
Roy
Raja
R
Sikora
Sadiq S
SS
Kumar
Rajesh
R
Husain
Mazhar
M
Khetrapal
C L
CL
Gupta
Rakesh K
RK
D000818:Animals; D003401:Creatine / Q000378:metabolism; D003551:Cysticercosis / Q000175:diagnosis* / Q000378:metabolism; D003937:Diagnosis, Differential; D004443:Echinococcosis / Q000175:diagnosis* / Q000378:metabolism; D005650:Fumarates / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008293:Malates / Q000378:metabolism; D011522:Protons; D012756:Sheep
D005650:Fumarates; D008293:Malates; D011522:Protons; C030298:malic acid; C032005:fumaric acid; D003401:Creatine