Non-covalent and semi-covalent molecularly imprinted polymers for selective on-line solid-phase extraction of 4-nitrophenol from water samples.
Two molecularly imprinted polymers (MIPs) have been synthesised for the selective extraction of 4-nitrophenol (4-NP) from water samples. One polymer was synthesised via a non-covalent approach and the other via a semi-covalent approach. The selectivity of the polymers for 4-NP was evaluated when these polymers were applied in on-line solid-phase extraction (MISPE) coupled to reversed-phase HPLC. The MISPE conditions for both MIPs were optimised and a clean-up step was included to eliminate non-specific interactions. Differences between the two MIPs were observed with the non-covalent MIP being the more selective of the two, whereas the recoveries were slightly higher for the semi-covalent MIP. The performance of the imprinted polymers in the MISPE of real water samples was also evaluated.
Caro
Ester
E
Department de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, Tarragona, Spain.
Masqué
Nuria
N
Marcé
Rosa M
RM
Borrull
Francesc
F
Cormack
Peter A G
PA
Sherrington
David C
DC
D002853:Chromatography, Liquid / Q000379:methods*; D009596:Nitrophenols / Q000302:isolation & purification*; D011108:Polymers / Q000737:chemistry*; D012680:Sensitivity and Specificity; D014867:Water / Q000737:chemistry
D009596:Nitrophenols; D011108:Polymers; D014867:Water; C024836:4-nitrophenol