'Twist theory' for the roles of estrogen and testosterone in the process of spermatogenesis.
Estrogen and testosterone have different effects on different steps of spermatogenesis and for each step optimal levels of estrogen and testosterone are different. The effects of these hormones behave as if 'twisted' from one end to the other end of the spectrum of steps of spermatogenesis. A graphic model is presented to explain this 'Twist Theory'.
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Purushottam
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Sah
D000818:Animals; D004967:Estrogens / Q000494:pharmacology / Q000502:physiology*; D005246:Feedback; D005640:Follicle Stimulating Hormone / Q000502:physiology; D008297:Male; D008954:Models, Biological; D013091:Spermatogenesis / Q000187:drug effects / Q000502:physiology*; D013739:Testosterone / Q000494:pharmacology / Q000502:physiology*
D004967:Estrogens; D013739:Testosterone; D005640:Follicle Stimulating Hormone