Enzyme-catalysed oxygenation and deoxygenation routes to chiral thiosulfinates.
Enantioenriched thiosulfinates have been obtained by dioxygenase- and chloroperoxidase-catalysed oxidation of 1,2-disulfides and dimethyl sulfoxide reductase-catalysed deoxygenation.
School of Chemistry, Queen's University of Belfast, Belfast, UK BT9 5AG.
Derek R
DR
Boyd
Narain D
ND
Sharma
Martina A
MA
Kennedy
Steven D
SD
Shepherd
John F
JF
Malone
André
A
Alves-Areias
Robert
R
Holt
Stig G
SG
Allenmark
Malin A
MA
Lemurell
Howard
H
Dalton
Heather
H
Luckarift
D000150:Acinetobacter / Q000201:enzymology; D002384:Catalysis; D002711:Chloride Peroxidase / Q000737:chemistry; D002954:Citrobacter / Q000201:enzymology; D049308:Dioxygenases; D004798:Enzymes / Q000737:chemistry*; D007202:Indicators and Reagents; D009097:Multienzyme Complexes / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D010105:Oxygenases / Q000737:chemistry; D016958:Pseudomonas putida / Q000201:enzymology; D013237:Stereoisomerism; D013886:Thiosulfonic Acids / Q000737:chemistry*
D004798:Enzymes; D007202:Indicators and Reagents; D009097:Multienzyme Complexes; D013886:Thiosulfonic Acids; D002711:Chloride Peroxidase; D010105:Oxygenases; D049308:Dioxygenases; C038703:naphthalene dioxygenase; C023172:toluene dioxygenase; D010100:Oxygen