[Correlation between self-reported drug use and the results of hair analysis in detoxification and methadone treatment patients].
Hair analysis offers the possibility of revealing an individual's recent history of drug exposure beginning at sampling day and dating back over a period of weeks or months. This feature of hair analysis can be applied in clinical setting for monitoring drug use by addicted patients being rehabilitated. The aim of this study was to apply determination of major opiates and amphetamines in hair to confirm medical interview made by a physician in detoxification and methadone treatment patients. These assays used gas chromatography coupled to mass spectrometry (GC/MS) for opiates and liquid chromatography coupled to atmospheric pressure chemical ionisation mass spectrometry (LC/MS-APCI) for amphetamines. Most unconfirmed interview data were in the group of detoxification patients. Four methadone patients were negative for opiates.
Instytut Ekspertyz Sadowych im. Prof. dra Jana Sehna w Krakowie. rstanasz@ies.krakow.pl
Roman
R
Stanaszek
Wojciech
W
Piekoszewski
Beata
B
Karakiewicz
Tadeusz
T
Kozielec
D000328:Adult; D002853:Chromatography, Liquid / Q000379:methods; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006197:Hair / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008658:Inactivation, Metabolic; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D009294:Narcotics / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D012650:Self Disclosure; D019966:Substance-Related Disorders / Q000534:rehabilitation*; D016896:Treatment Outcome
D009294:Narcotics; D008691:Methadone