Molecular interactions in biofilms.
A biofilm may be defined as a microbially derived, sessile community characterized by cells that attach to an interface, embed in a matrix of exopolysaccharide, and demonstrate an altered phenotype. This review covers the current understanding of the nature of biofilms and the impact that molecular interactions may have on biofilm development and phenotype using the motile gram-negative rod Pseudomonas aeruginosa and the nonmotile gram-positive cocci Staphylococcus aureus as examples.
Shirtliff
Mark E
ME
Center for Biofilm Engineering, Montana State University, Bozeman 59717, USA.
Mader
Jon T
JT
Camper
Anne K
AK
D018441:Biofilms / Q000254:growth & development*; D002450:Cell Communication / Q000235:genetics; D015964:Gene Expression Regulation, Bacterial; D010641:Phenotype; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000254:growth & development; D013211:Staphylococcus aureus / Q000235:genetics / Q000254:growth & development