[Carcinoma developing in extragonadal endometriosis--analysis of two cases].
Two cases of invasive carcinoma developing in extragonadal endometriosis are presented. Each case had a different clinical course. In addition to routine histopathologic studies immunohistochemical studies to assess the expression of cytoceratin and glycoprotein CD-44 were performed. In both cases CK-7 expression was higher in malignancy then in the endometrioid tissue. Very high expression of CD-44 protein (marker of metastatic potential) was found in patients with poor progress of the disease.
Kliniki Nowotworów Narzadów Płciowych Kobiecych Centrum Onkologii Instytutu w Warszawie.
Grzegorz
G
Panek
Jan
J
Zieliński
D000005:Abdomen / Q000473:pathology / Q000601:surgery; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002277:Carcinoma / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000737:chemistry; D004715:Endometriosis / Q000150:complications* / Q000473:pathology; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D018960:Hyaluronan Receptors / Q000032:analysis; D053552:Keratin-7; D007633:Keratins / Q000032:analysis; D010502:Perineum / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D015854:Up-Regulation
D014408:Biomarkers, Tumor; D018960:Hyaluronan Receptors; C507497:KRT7 protein, human; D053552:Keratin-7; D007633:Keratins