Chronic actinic dermatitis developed during phototherapy for psoriasis.
A patient with psoriasis vulgaris had been successfully treated with PUVA and UVB therapy. During maintenance phototherapy, he suddenly became photosensitive and developed eczematous eruption. Minimal response doses to UVB and UVA were extremely low--1.09 mJ/cm2 and 0.3 J/cm2, respectively. No chemical substances were identified as the responsible photosensitizer. The condition was diagnosed as chronic actinic dermatitis (CAD). PUVA therapy was unsatisfactory because it was not possible to administer an adequate dose of UVA. Oral cyclosporine, topical corticosteroid and sunscreen were used with beneficial therapeutic effects on psoriasis and CAD. As far as we know, the development of CAD during phototherapy has not been previously reported.
Department of Dermatology, Kansai Medical University, Osaka, Japan.
N
N
Fujii
N
N
Uetsu
M
M
Hamakawa
S
S
Futamura
H
H
Okamoto
T
T
Horio
D002908:Chronic Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy / Q000009:adverse effects*; D010787:Photosensitivity Disorders / Q000209:etiology*; D011565:Psoriasis / Q000188:drug therapy / Q000628:therapy*; D011829:Radiation Dosage; D014467:Ultraviolet Therapy / Q000009:adverse effects*