[Growth factors in pregnancy complications with preeclampsia].
The aim of the study was to determine the concentrations of TGF-beta, PDGF and VEGF growth factors in peripheral blood. The examinations were carried out in the group of pregnant women with preeclampsia. The results were compared to those obtained in a control group of healthy pregnant women. The statistically significant increase in all examined growth factors was observed in women with preeclampsia in comparison to healthy women. The results suggest that growth factors may play an important role in etiology and pathophysiology of preeclampsia.
Kliniki Perinatologii i Połoznictwa, Akademii Medycznej w Białymstoku.
Dariusz Adam
DA
Bielecki
Ewa
E
Klonowska-Dziatkiewicz
Sławomir
S
Jarocki
Jan
J
Urban
D000328:Adult; D016022:Case-Control Studies; D016228:Endothelial Growth Factors / Q000097:blood*; D005260:Female; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood*; D008222:Lymphokines / Q000097:blood*; D010982:Platelet-Derived Growth Factor / Q000378:metabolism*; D011225:Pre-Eclampsia / Q000097:blood* / Q000209:etiology; D011247:Pregnancy; D011263:Pregnancy Trimester, Third / Q000097:blood; D016212:Transforming Growth Factor beta / Q000097:blood*; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D016228:Endothelial Growth Factors; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines; D010982:Platelet-Derived Growth Factor; D016212:Transforming Growth Factor beta; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors