Labor and cost requirements of two commercial assays for qualitative molecular detection of hepatitis C virus.
The Bayer transcription-mediated amplification (TMA) and the Roche PCR Amplicor version 2.0 molecular assays for the qualitative detection of hepatitis C virus were compared for cost, hands-on time, assay duration, and complexity. The TMA assay compares well to PCR and may be especially useful for laboratories with large numbers of test requests.
Department of Pathology, Stanford University School of Medicine, California, USA.
Iris
I
Schrijver
Ellen Jo
EJ
Baron
D003365:Costs and Cost Analysis; D006280:Health Workforce; D016174:Hepacivirus / Q000302:isolation & purification* / Q000502:physiology; D006526:Hepatitis C / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D021141:Nucleic Acid Amplification Techniques / Q000191:economics* / Q000379:methods; D016133:Polymerase Chain Reaction / Q000191:economics; D012367:RNA, Viral / Q000032:analysis*; D011933:Reagent Kits, Diagnostic / Q000191:economics*; D013997:Time Factors; D014158:Transcription, Genetic; D019562:Viral Load
D012367:RNA, Viral; D011933:Reagent Kits, Diagnostic