Hemispheric lateralization of the processing of consonant-vowel syllables (formant transitions): effects of stimulus characteristics and attentional demands on evoked magnetic fields.
It is still unsettled in how far temporal resolution of dynamic acoustic events (formant transitions) or phonetic/linguistic processes contribute to predominant left-hemisphere encoding of consonant-vowel syllables. To further elucidate the underlying mechanisms, evoked magnetic fields in response to consonant-vowel events (synthetic versus spoken) were recorded (oddball design: standards=binaural/ba/, deviants=dichotic/ba/-/da/; 20 right-handed subjects) under different attentional conditions (visual distraction versus stimulus identification). Spoken events yielded a left-lateralized peak phase of the mismatch field (MMF; 150-200ms post-stimulus onset) in response to right-ear deviants during distraction. By contrast, pre-attentive processing of synthetic items gave rise to a left-enhanced MMF onset (100ms), but failed to elicit later lateralization effects. In case of directed attention, synthetic deviants elicited a left-pronounced MMF peak resembling the pre-attentive response to natural syllables. These interactions of MMF asymmetry with signal structure and attentional load indicate two distinct successive left-lateralization effects: signal-related operations and representation of 'phonetic traces'. Furthermore, a right-lateralized early MMF component (100ms) emerged in response to natural syllables during pre-attentive processing and to synthetic stimuli in case of directed attention. Conceivably, these effects indicate right hemisphere operations prior to phonetic evaluation such as periodicity representation. Two distinct time windows showed correlations between dichotic listening performance and ear effects on magnetic responses reflecting early gain factors (ca. 75ms post-stimulus onset) and binaural fusion strategies (ca. 200ms), respectively. Finally, gender interacted with MMF lateralization, indicating different processing strategies in case of artificial speech signals.
Hertrich
Ingo
I
Department of Neurology, University of Tübingen, Otfried-Müller-Street 47, Germany. ingo.hertrich@uni-tuebingen.de
Mathiak
Klaus
K
Lutzenberger
Werner
W
Ackermann
Hermann
H
D000328:Adult; D001288:Attention / Q000502:physiology*; D003627:Data Interpretation, Statistical; D004007:Dichotic Listening Tests; D004574:Electromagnetic Fields; D005072:Evoked Potentials, Auditory / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D011597:Psychomotor Performance / Q000502:physiology; D012727:Sex Characteristics; D013067:Speech Perception / Q000502:physiology*