Three new pyridoacridine type alkaloids from a singaporean ascidian.
Two new pyridoacridine alkaloids, kuanoniamines E and F, and a new ring-opened pyridoacridine alkaloid, subarine, were isolated from a Singaporean ascidian. Also isolated were known pyridoacridine alkaloids ascididemin and kuanoniamines A and D. The structures of the alkaloids were determined by spectroscopic methods.
Nilar
Nilar
N
Centre for Natural Product Research, Institute of Molecular and Cell Biology, Singapore Science Park, 128041, Singapore.
Sidebottom
Philip J
PJ
Carté
Brad K
BK
Butler
Mark S
MS
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012846:Singapore; D021241:Spectrometry, Mass, Electrospray Ionization; D014561:Urochordata / Q000737:chemistry*
D000470:Alkaloids; D006576:Heterocyclic Compounds, 4 or More Rings; C466607:kuanoniamine E; C466608:kuanoniamine F; C466609:subarine