Myocardial tagging with 3D-CSPAMM.
OBJECTIVE
To introduce a true three-dimensional (3D) tagging technique for the assessment of myocardial tissue motion.


METHODS
To generate a 3D tagging grid, a complementary spatial modulation of magnetization (CSPAMM) was applied in three spatial directions. Imaging was performed using a conventional fast 3D gradient-echo sequence. For automatic analysis of the 3D-CSPAMM data set, evaluation software, based on a 3D extension of the HARP technique, was used.


RESULTS
Successful application of the 3D-CSPAMM technique in healthy subjects allowed the accurate determination of quantitative 3D motion patterns in the human heart.


CONCLUSIONS
3D-CSPAMM may contribute to the quantification of the local 3D myocardial motion pattern throughout the cardiac cycle.
Institute for Biomedical Engineering, University and ETH Zurich, Switzerland.
Salome
S
Ryf
Marcus A
MA
Spiegel
Michael
M
Gerber
Peter
P
Boesiger
D006321:Heart / Q000033:anatomy & histology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009200:Myocardial Contraction / Q000502:physiology*