Asymmetric reduction of azirines; a new route to chiral aziridines.
The first enantioselective reduction of aromatic 2H-azirines yields aziridines in up to 70% ee, using the aminoalcohol-[RuCl2(p-cymene)]2 catalyzed asymmetric transfer hydrogenation reaction.
Roth
Peter
P
Institute of Chemistry, Department of Organic Chemistry, Box 531, SE-751 21 Uppsala, Sweden.
Andersson
Pher G
PG
Somfai
Peter
P
D001388:Aziridines / Q000138:chemical synthesis* / Q000737:chemistry; D006865:Hydrogenation; D013237:Stereoisomerism
D001388:Aziridines