Organization and administration of the NIDCD/VA Hearing Aid Clinical Trial.
This article describes the organization and administration of the NIDCD/VA Hearing Aid Clinical Trial. The trial involved a total of 360 patients with bilateral, sensorineural hearing loss from eight VA Medical Centers to study three different hearing aid circuits in a three-period, three-treatment crossover design. Strong central coordination of such a complex multi-center clinical trial is essential to its success. The trial took more than 5 years to design, implement, and complete. This timeline is also described.
Henderson
William G
WG
Hines VA Cooperative Studies Program Coordinating Center, Hines, Illinois 60141, USA.
Larson
Vernon D
VD
Williams
David
D
Leuthke
Lynn
L
D002986:Clinical Trials as Topic; D006310:Hearing Aids; D006319:Hearing Loss, Sensorineural / Q000534:rehabilitation*; D006801:Humans; D012106:Research / Q000458:organization & administration