Substrate distortion by a beta-mannanase: snapshots of the Michaelis and covalent-intermediate complexes suggest a B(2,5) conformation for the transition state.
Ducros
Valérie M-A
VM
Department of Chemistry, Structural Biology Laboratory, The University of York, Heslington, York, YO10 5DD, UK.
Zechel
David L
DL
Murshudov
Garib N
GN
Gilbert
Harry J
HJ
Szabó
Lóránd
L
Stoll
Dominik
D
Withers
Stephen G
SG
Davies
Gideon J
GJ
D002384:Catalysis; D006031:Glycosylation; D006601:Hexoses / Q000737:chemistry* / Q000378:metabolism; D008361:Mannosidases / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D008968:Molecular Conformation; D044902:beta-Mannosidase
D006601:Hexoses; D008361:Mannosidases; D044902:beta-Mannosidase