Drift in the nucleoprotein gene of swine influenza virus (H1N1) causing respiratory disease in pigs.
The nucleoprotein (NP) gene of swine influenza H1N1 variant, A/Sw/Quebec/5393/91 (SwQc91) was sequenced. When compared with other H1N1 strains, 12 amino acid (aa) replacements were observed in the 101-484 aa region of the NP protein including two aas, 345 and 430, representing the unique lineage of swine viruses. Phylogenetic analysis showed a drift in the NP gene.
Dharam Jit S
DJ
Arora
D000818:Animals; D040961:Genetic Drift; D053118:Influenza A Virus, H1N1 Subtype; D009980:Influenza A virus / Q000145:classification / Q000201:enzymology / Q000235:genetics*; D009698:Nucleoproteins / Q000235:genetics*; D009976:Orthomyxoviridae Infections / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D012141:Respiratory Tract Infections / Q000662:veterinary / Q000821:virology*; D013552:Swine; D013553:Swine Diseases / Q000821:virology*
D009698:Nucleoproteins