Rasmussen's encephalitis followed by lupus erythematosus.
A 6-year-old female presented with right hemichorea, initially thought to be post-streptococcal, which subsequently progressed to a right dystonic hemiplegia. At 7 1/2 years she developed right focal and secondary generalized tonic-clonic seizures. These became intractable. A brain biopsy was consistent with Rasmussen's encephalitis (RE). At 9 1/2 years the child underwent a left hemispherectomy making a good recovery with resolution of seizures. At 12 years she presented with recurrent episodes of abdominal pain, fever, and malar rash with serological evidence of systemic lupus erythematosus (SLE). A possible link between RE and SLE is discussed.
Lascelles
K
K
Newcomen Centre, Guy's Hospital, London, UK. karine.lascelles@kcl.ac.uk
Dean
A F
AF
Robinson
Richard O
RO
D001706:Biopsy; D001921:Brain / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D019635:Neurosurgical Procedures; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18