[Relationship between estrogen, progesterone, total testosterone, androstenedione, and epidural growth factor in blood and breast cyst fluid].
In breast cyst fluid obtained from 50 patients age (47.1 +/- 2.3) sodium, potassium, oestrone (E1), oestradiol (E2) androgens, progesterone, (P) and Epidermal Growth Factor--EGF were determined. Markedly higher oestrogens, progesterone, testosterone, and EGF-levels were detected in cyst fluid than in blood. These data have confirmed previous results and have clearly shown that breast cyst fluid with high potassium (ratio K/Na > 1.0) contains more oestrogens, progesterone, testosterone, androstenedione and EGF than the group with low electrolyte ratio. This finding might be put in correlation with the fact that patients with high ratio K/Na may a higher risk of breast cancer than those with low electrolyte ratio.
Samodzielnej Pracowni Menopauzy i Andropauzy P.A.M. w Szczecinie.
Stanisław
S
Stanosz
Barbara
B
Blicharczyk-Zalewska
Grazyna
G
Wilk
Maria
M
Kubisa
D000328:Adult; D000735:Androstenedione / Q000097:blood / Q000378:metabolism*; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D004815:Epidermal Growth Factor / Q000097:blood / Q000378:metabolism*; D004967:Estrogens / Q000097:blood / Q000378:metabolism*; D005122:Exudates and Transudates / Q000378:metabolism; D005260:Female; D005348:Fibrocystic Breast Disease / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D011188:Potassium / Q000097:blood / Q000378:metabolism; D011374:Progesterone / Q000097:blood / Q000378:metabolism*; D012307:Risk Factors; D012964:Sodium / Q000097:blood / Q000378:metabolism; D013739:Testosterone / Q000097:blood / Q000378:metabolism*
D015415:Biomarkers; D004967:Estrogens; D013739:Testosterone; D000735:Androstenedione; D011374:Progesterone; D004815:Epidermal Growth Factor; D012964:Sodium; D011188:Potassium