[Changes in myocardial damage markers after radiofrequency ablation in patients with arrhythmias].
The aim of this study was to evaluate myocardial cell damage after radiofrequency ablation (RFA), one of the most effective methods for the treatment of arrhythmias. Thirty patients aged 30.4 +/- 8.6 years were examined. Biochemical parameters were evaluated repeatedly 6-18 h after RFA. Positive troponin T (Tn-T) test and increased CK-Mb activity (p < 0.22) were observed in 8 patients (group 1), while in group II Tn-T test was negative. Biochemical findings in group I correlated with the results of ECG body surface mapping (STT) (negative area), duration and number of RFA lesions. Myocardial damage was detected using 3 cardiac markers: myo/CK-Mb and Tn-T. These testing should be carried out in due time repeatedly, in order to catch the STT maps and biochemical parameters were in high correlation after RFA. Presumably, T-wave abnormalities in Tn-T-negative group after RFA were due to the cardiac memory phenomenon. Myo/CK-Mb after RFA in Tn-T-positive group coincided with that in acute myocardial infarction. Hence, myocardial damage after RFA can be confirmed by the Tn-T test, which is helpful in the differential diagnosis of minor myocardial damage and cardiac memory phenomenon.
M O
MO
Egorova
E Z
EZ
Golukhova
N B
NB
Teriaeva
T A
TA
Zhvaniia
V A
VA
Bazaev
M V
MV
Kruglova
D000328:Adult; D017115:Catheter Ablation / Q000009:adverse effects*; D003402:Creatine Kinase / Q000097:blood*; D052279:Creatine Kinase, MB Form; D004562:Electrocardiography; D006321:Heart / Q000503:physiopathology; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D009206:Myocardium / Q000378:metabolism*; D009211:Myoglobin / Q000032:analysis*; D013614:Tachycardia, Paroxysmal / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D020107:Troponin T / Q000097:blood*; D014927:Wolff-Parkinson-White Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*
D007527:Isoenzymes; D009211:Myoglobin; D020107:Troponin T; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form