[The development of peptide nucleic acid in gene regulation].
Peptide nucleic acid(PNA) is a kind of artificial DNA mimic. PNA hybridizes with DNA or RNA by means of Watson-Crick's base-pairs complementary with high stability, affinity and selectivity. PNA not only regulates. DNA replication, but also adjusts DNA transcription (or reverse transcription) and translation. Many applications have been explored as a new kind of molecular biological tool and a gene-targeting strategy.
Gong
Xia
X
Food College of Southern Yangtze University, Wuxi 214036, China. gongxia11@263.net
Le
Guo-Wei
GW
Shi
Yong-Hui
YH
D005786:Gene Expression Regulation / Q000187:drug effects*; D020135:Peptide Nucleic Acids / Q000494:pharmacology*; D014176:Protein Biosynthesis / Q000187:drug effects; D014158:Transcription, Genetic / Q000187:drug effects
D020135:Peptide Nucleic Acids