[The electric properties of fiber surface and the toxicity of asbestos].
Thermal treatment, autoclaving and their combination yielded 3 samples of chrysotile-asbestos. With these, as compared with parent Type PRZh-1-50 Bazhenov chrysotile, the structure of fibers deteriorated and the number of negative discharges increased in the first two samples; the superficial structure substantially increased and the number of positive centers greatly decreased in the third sample. The ratio of positive to negative centers was less in all treated samples than that in the parent one, it decreased particularly during combined treatment. In this sample, hemolytic and mutagenic activity and cytotoxicity were substantially decreased; carcinogenic activity was greatly decreased (by 4 times) (as shown by the pleural mesothelioma indication test during intrapleural administration to rats). Thermal treatment and autoclaving insignificantly lowered the hemolytic activity and mutagenicity; carcinogenicity of these samples was much less (by 2.3 and 2 times) than that of parent chrysotile.
Pylev
L N
LN
Vasil'eva
L A
LA
Krinari
G A
GA
Bakhtin
A I
AI
Vezentsev
A I
AI
Zubakova
L E
LE
D000818:Animals; D001194:Asbestos / Q000009:adverse effects* / Q000737:chemistry*; D004560:Electricity; D019016:Mineral Fibers; D009369:Neoplasms / Q000209:etiology; D051381:Rats; D017208:Rats, Wistar
D019016:Mineral Fibers; D001194:Asbestos