Resistance to activated protein C and digital thrombosis.
Resistance to activated protein C is a newly described genetic coagulation disorder previously only reported in patients with venous thromboembolism or central arterial embolism (cerebral or coronary). We report this defect in association with digital artery thrombosis and describe the pathophysiology of this disorder.
Indiana Hand Center, USA.
Jeffrey A
JA
Rodgers
Drew R
DR
Engles
Richard S
RS
Idler
D020016:Activated Protein C Resistance / Q000150:complications / Q000503:physiopathology*; D000328:Adult; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D010960:Plasminogen Activators / Q000627:therapeutic use; D013927:Thrombosis / Q000150:complications / Q000235:genetics / Q000503:physiopathology*; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator