Delayed lactogenesis II secondary to gestational ovarian theca lutein cysts in two normal singleton pregnancies.
Hyperreactio luteinalis is an unusual condition in which, during pregnancy, both ovaries are enlarged by multiple theca lutein cysts that produce a high level of testosterone. Several weeks postpartum, the cysts resolve and testosterone level returns to normal. Two case studies are presented in which mothers with gestational ovarian theca lutein cysts experienced delayed lactogenesis II. The elevated testosterone at the time of birth suppressed milk production. Once the testosterone level dropped to approximately 300 ng/dL, milk production began. After the initial delay, both mothers breastfed their infants without supplementation.
Temple University Medical School, USA.
Kathleen L
KL
Hoover
Laurie H
LH
Barbalinardo
Maria Pia
MP
Platia
D000328:Adult; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007775:Lactation Disorders / Q000209:etiology*; D008184:Luteal Cells / Q000473:pathology*; D010048:Ovarian Cysts / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D013739:Testosterone / Q000097:blood; D013799:Theca Cells / Q000473:pathology*
D013739:Testosterone