Linker histone H1M transcripts mark the developing germ line in zebrafish.
Maternally synthesised factors contribute to the establishment of the germ cell lineage in lower vertebrates. In zebrafish, germ-soma segregation appears to be completed by the late blastula stage of development. To search for new germ cell factors in the zebrafish, we have used subtractive cDNA cloning. Here we report that linker histone H1M transcripts mark the germ line from the early gastrulation up to 18 h post-fertilisation.
Sars International Centre for Marine Molecular Biology, Bergen High Technology Centre, Thormøhlensgt 55, N-5008 Bergen, Norway.
Karin
K
Wibrand
Lisbeth Charlotte
LC
Olsen
D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D005854:Germ Cells / Q000378:metabolism; D006657:Histones / Q000235:genetics*; D017403:In Situ Hybridization; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D015027:Zebrafish / Q000196:embryology* / Q000235:genetics* / Q000378:metabolism; D029961:Zebrafish Proteins / Q000235:genetics*
D018076:DNA, Complementary; D006657:Histones; D012333:RNA, Messenger; D029961:Zebrafish Proteins