[Studies on pharmacognostic identification and quality control standards for hongqu].
OBJECTIVE
To develop effective methods for quality control of the traditional Chinese drug Hongqu.


METHODS
TLC and microscopic identification were performed. HPLC was used to determine the content of lovastatin.


RESULTS
A lot of hyphae and spores in Hongqu were observed under microscope. The spot of lovastatin was found on the TLC chromatogram. The standard curve of lovastatin by HPLC was linera in the range of 5 micrograms/ml-100 micrograms/ml. The average recovery of lovastatin was 96.4%, RSD 3.68%, n = 5.


CONCLUSIONS
The methods are simple, sensitive and accurate. These studies provide the scientific basis for quality evaluation and quality control of Hongqu.
Shenyang Military Region General Hospital, Shenyang 110015.
H
H
Song
T
T
Guo
Y
Y
Zhang
H
H
Mi
Q
Q
Zhang
D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D003720:Densitometry; D008148:Lovastatin / Q000032:analysis*; D032741:Monascus / Q000737:chemistry*; D010598:Pharmacognosy; D011208:Powders; D011786:Quality Control
D011208:Powders; D008148:Lovastatin