The Drosophila melanogaster Ku70 coding sequence is wild-type in mus309 mutants.
Drosophila melanogaster mus309 mutations have been identified as being in the Ku70 gene, encoding one subunit of the DNA-dependent protein kinase. However, recent work has suggested that these mutations are in the Bloom's syndrome homologue. Here, we demonstrate that the coding sequence of Ku70 gene is indeed wild-type in two mus309 mutant lines.
Institute of Genetics, University of Nottingham, Queens Medical Centre, UK.
Helen R
HR
Nicholas
John F Y
JF
Brookfield
D000818:Animals; D034961:Antigens, Nuclear / Q000235:genetics*; D004265:DNA Helicases; D004268:DNA-Binding Proteins / Q000235:genetics*; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D000072200:Ku Autoantigen; D009154:Mutation
D034961:Antigens, Nuclear; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D004265:DNA Helicases; C106893:XRCC5 protein, human; C000606509:Xrcc6 protein, human; D000072200:Ku Autoantigen