Case series: Adderall augmentation of serotonin reuptake inhibitors in childhood-onset obsessive compulsive disorder.
Current pharmacological treatment of obsessive compulsive disorder involves the use of selective serotonin reuptake inhibitors (SSRIs). However, a large proportion of patients does not respond fully to these medications despite receiving optimal doses and concomitant cognitive-behavioral therapy. Finding efficacious augmentation strategies has become an important goal of researchers and clinicians working with this population. In this case series, we describe four patients with childhood-onset obsessive compulsive disorder, and with partial or no response to SSRI treatment, who subsequently had a reduction of their symptoms with Adderall augmentation.
Owley
Thomas
T
Section of Child and Adolescent Psychiatry, Department of Psychiatry, University of Chicago, Illinois 60637, USA. towley@yoda.bsd.uchicago.edu
Owley
Soyna
S
Leventhal
Bennett
B
Cook
Edwin H
EH
D000328:Adult; D017668:Age of Onset; D000662:Amphetamines / Q000627:therapeutic use*; D002648:Child; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000523:psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
D000662:Amphetamines; D017367:Selective Serotonin Reuptake Inhibitors; C090411:Adderall