Suppression of eye movements improves balance.
The aim of this study was to investigate the possible interaction of vestibulo-ocular and vestibulo-spinal functions. Spontaneous eye movements and anterior-posterior and lateral body sway were recorded simultaneously in 10 patients with vestibular neuritis (Experiment 1) and in 11 healthy subjects (Experiment 2) while all subjects wore a mask that allowed fixation of a head-fixed target. For the healthy subjects, there was no significant difference in postural sway for the conditions of eyes open in darkness and fixation of the head-fixed target. For the patients, the question was whether transient suppression of the spontaneous nystagmus by fixating the target affected excessive body sway or whether modulation of nystagmus and postural sway were largely independent. The mean peak slow-phase velocity of the spontaneous nystagmus decreased from 13.5 +/- 5.6 to 4.3 +/- 2.4 degrees /s during fixation. The suppression of nystagmus also reduced postural sway while standing on foam rubber. Mean value decreased from 25.2 +/- 7.6 to 16.2 +/- 7.7 mm (right-left root mean square values; ANOVA, P = 0.003). Since a head-fixed target was used to suppress spontaneous eye movements, the data cannot be explained by any stabilizing effect of afferent visual cues. Instead, ocular motor efference copy signals or reafferences may have contributed to the postural instability of patients with vestibular neuritis, which would explain the reduction of postural sway during fixation suppression of the nystagmus. Thus, ocular motor signals rather than afferent visual cues about retinal slip are used for visual control of postural sway, at least in this experimental paradigm.
Jahn
Klaus
K
Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany. kjahn@nefo.med.uni-muenchen.de
Strupp
Michael
M
Krafczyk
Siegbert
S
Schüler
Olaf
O
Glasauer
Stefan
S
Brandt
Thomas
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003624:Darkness; D005133:Eye Movements / Q000502:physiology*; D005260:Female; D005403:Fixation, Ocular; D006257:Head; D006801:Humans; D008297:Male; D008875:Middle Aged; D009760:Nystagmus, Physiologic; D004856:Postural Balance / Q000502:physiology*; D012016:Reference Values; D012149:Restraint, Physical; D020338:Vestibular Neuronitis / Q000503:physiopathology*