MR-axillography oriented surgical sampling for assessment of nodal status in the selection of patients with breast cancer for axillary lymph nodes dissection.
BACKGROUND
We have reported that magnetic resonance axillography (MR-axillography) is the best method for assessing lymph node size and representing the relation of the lymph node to normal anatomy.


METHODS
The four largest nodes on MR-axillography were sampled in 62 consecutive patients with breast cancer undergoing axillary clearance. Axillary clearance yielded a mean of 17.0 (range 5-28) nodes.


RESULTS
A method of preliminary sampling of four nodes in the axilla oriented by MR-axillography was assessed in all cases, 22 of whom were histologically node positive. Based on the sampled nodes, lymph node metastases were detected in 20 of 22 (91%) of the node-positive patients. Based on the sampled nodes, of the 19 patients with macrometastatic nodes, lymph node metastases were detected in all 19 (100%), but only in 1 of the 3 (33%) patients with only one micrometastatic node.


CONCLUSIONS
This experience indicates that sampling the four largest nodes by MR-axillography orientation accurately identifies patients with macrometaststic nodes. This result may be comparable to that of surgical sampling performed by the most skilled surgeons.
Suzuma
Takaomi
T
Department of Surgery, Affiliated Kihoku Hospital, Wakayama Medical University, 219 Myouji, Katsuragicho, Itogun, Japan. suzuma@mail.wakayama-med.ac.jp
Sakurai
Takeo
T
Yoshimura
Goro
G
Umemura
Teiji
T
Tamaki
Takeshi
T
Yang
Qi-Feng
QF
Oura
Shoji
S
Naito
Yasuaki
Y
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging / Q000592:standards*; D008875:Middle Aged; D011237:Predictive Value of Tests; D011859:Radiography; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*