Pulsed-microwave-induced thermoacoustic tomography: filtered backprojection in a circular measurement configuration.
Our study on pulsed-microwave-induced thermoacoustic tomography in biological tissues is presented. A filtered backprojection algorithm based on rigorous theory is used to reconstruct the cross-sectional image from a thermoacoustic measurement in a circular configuration that encloses the sample under study. Specific details describing the measurement of thermoacoustic waves and the implementation of the reconstruction algorithm are discussed. A two-dimensional (2D) phantom sample with 2 mm features can be imaged faithfully. Through numerical simulation, the full width half-maximum (FWHM) of the point-spread function (PSF) is calculated to estimate the spatial resolution. The results demonstrate that the circular measurement configuration combined with the filtered backprojection method is a promising technique for detecting small tumors buried in biological tissues by utilizing microwave absorption contrast and ultrasound spatial resolution (approximately mm).
Optical Imaging Laboratory, Texas A&M University, College Station 77843-3120, USA.
Minghua
M
Xu
Lihong V
LV
Wang
D000162:Acoustics / Q000295:instrumentation; D000465:Algorithms; D003198:Computer Simulation; D007089:Image Enhancement / Q000379:methods*; D008872:Microwaves; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013817:Thermography / Q000295:instrumentation / Q000379:methods*; D014463:Ultrasonography / Q000295:instrumentation / Q000379:methods*