[Antibodies seroprevalence for mycoplasma pneumoniae antigens in patients with bronchial asthma].
Microorganisms causing respiratory system infections, mainly viruses but also bacteria, among which there are atypical such as Chlamydophila pneumoniae, play a role in etiopathogenesis of bronchial asthma. Mycoplasma pneumoniae is suggested to take part in the initiation and the bronchial asthma exacerbation. The aim of the paper was to determine the frequency of occurrence of anti-Mycoplasma pneumoniae antibodies in serum of patients suffering from bronchial asthma in comparison with the control group of healthy persons. The presence of IgG, IgM and IgA class anti-Mycoplasma pneumoniae antibodies was assessed by immunoenzymatic assay ELISA. Serologic markers of Mycoplasma pneumoniae infection were more frequently observed in patients with bronchial asthma (15%) than in the control group (5.13%). The diagnosis of Mycoplasma pneumoniae infection is especially important in patients with bronchial asthma. The pathogen causing bronchial hyperreactivity is eliminated by the appropriate antibiotic therapy, which allows reducing the dose of inhaled corticosteroids. The immunoenzymatic assay determining the level and class of specific antibodies to find mycoplasmatic infection quickly and precisely.
Katedry i Zakładu Mikrobiologii, Slaskiej Akademii Medycznej w Katowicach.
Daniela
D
Friedek
Alicja
A
Ekiel
Patryk
P
Szulakowski
Małgorzata
M
Romanik
D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D001249:Asthma / Q000150:complications* / Q000276:immunology; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D009177:Mycoplasma pneumoniae / Q000276:immunology*; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology; D011044:Poland / Q000453:epidemiology; D016036:Seroepidemiologic Studies
D000907:Antibodies, Bacterial; D015415:Biomarkers; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M