To DRiP or not to DRiP: generating peptide ligands for MHC class I molecules from biosynthesized proteins.
Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Room 211 Bldg 4, 4 Center Drive, Bethesda, MD 20892-0440, USA. jyewdell@nih.gov
Jonathan
J
Yewdell
D000818:Animals; D003546:Cysteine Endopeptidases / Q000502:physiology; D003600:Cytosol / Q000378:metabolism; D015395:Histocompatibility Antigens Class I / Q000378:metabolism*; D006801:Humans; D008024:Ligands; D008213:Lymphocyte Activation; D009097:Multienzyme Complexes / Q000502:physiology; D010455:Peptides / Q000378:metabolism*; D046988:Proteasome Endopeptidase Complex; D014176:Protein Biosynthesis; D012270:Ribosomes / Q000378:metabolism*; D013601:T-Lymphocytes / Q000276:immunology; D025801:Ubiquitin / Q000378:metabolism
D015395:Histocompatibility Antigens Class I; D008024:Ligands; D009097:Multienzyme Complexes; D010455:Peptides; D025801:Ubiquitin; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex