Kinetic resolution of beta- and gamma-hydroxy sulfides by fungal lipase from Humicola lanuginosa.
Racemic beta- and gamma-hydroxy sulfides were resolved by Humicola lanuginosa lipase catalyzed transesterification using vinyl acetate both as acyl donor and solvent. The effect of substituents and spacer length on rate of reaction and enantioselectivity is observed.
Satwinder
S
Singh
Subodh
S
Kumar
Swapandeep Singh
SS
Chimni
D000215:Acylation; D002384:Catalysis; D005658:Fungi / Q000201:enzymology*; D007700:Kinetics; D008049:Lipase / Q000378:metabolism*; D015394:Molecular Structure; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013440:Sulfides / Q000737:chemistry* / Q000378:metabolism*
D013440:Sulfides; D008049:Lipase