Databases and tools for browsing genomes.
To maximize the value of genome sequences they need to be integrated with other types of biological data and with each other. The entire collection of data then needs to be made available in a way that is easy to view and mine for complex relationships. The recently determined vertebrate genome sequences of human and mouse are so large that building the infrastructure to manage these datasets is a major challenge. This article reviews the database systems and tools for analysis that have so far been developed to address this.
Birney
Ewan
E
European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, United Kingdom. birney@ebi.ac.uk
Clamp
Michele
M
Hubbard
Tim
T
D000818:Animals; D019992:Databases as Topic; D005823:Genetics; D016678:Genome; D006801:Humans; D020407:Internet; D012984:Software