A novel approach to the synthesis of bicyclic lactones via an interrupted Nazarov reaction of gem-divinyl dihydrofurans.
[reaction: see text] A facile Lewis acid induced interrupted Nazarov reaction of gem-divinyl dihydrofurans to bicyclic lactones is described.
Organic Chemistry Division, Regional Research Laboratory (CSIR), Trivandrum, India. gvn@csrrltrd.ren.nic.in
Vijay
V
Nair
S
S
Bindu
V
V
Sreekumar
Angele
A
Chiaroni
D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis; D003500:Cyclization; D003517:Cyclopentanes / Q000737:chemistry; D005663:Furans / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis*; D014753:Vinyl Compounds / Q000737:chemistry
D019086:Bridged Bicyclo Compounds, Heterocyclic; D003517:Cyclopentanes; D005663:Furans; D007783:Lactones; D014753:Vinyl Compounds; C007201:cyclopentanone