Effects of heavy resistance/power training on maximal strength, muscle morphology, and hormonal response patterns in 60-75-year-old men and women.
Eleven women (TRW; 64 +/- 4 yrs) and ten men (TRM; 65 +/- 5 yrs) participated in the strength/power training twice a week for 24 weeks. Basal concentrations of serum total and free testosterone, growth hormone (GH), dehydroepiandrosterone sulfate (DHEAS), cortisol and sex hormone binding globulin (SHBG) as well as acute responses of serum total and free testosterone, growth hormone (GH) were measured. Maximal 1RM strength in the squat, chair rise time and muscle fibre distribution and areas of type I and IIa and IIb of the vastus lateralis were also examined. 1RM squat increased in TRW by 26 (SD10)% (p < .001), and in TRM by 35 (7)% (p < .001) and chair rise time improved in both groups (p < .001). Fibre areas increased in type I, (p < .01), IIa (p < .01) and IIb (p < .01) in TRM and type I (p < .05) and IIa (p < .05) in TRW. The proportion of type IIa increased from 31% to 43% (p < .05) in TRW and that of type IIb decreased from 27% to 17% (p < .05) in TRW and from 25% to 17% (p < .05) in TRM. Individual concentrations of testosterone/cortisol ratios correlated (r = 0.63; p < .05) with the individual increases in 1RM strength in TRW. The exercise sessions resulted in acute increases in serum GH in both groups (p < .05) with a further increase (p < .01) up to 10 minutes post-loading in TRM at post-training.
Department of Biology of Physical Activity and Neuromuscular Research Center, University of Jyväskylä, Finalnd.
Keijo
K
Häkkinen
William J
WJ
Kraemer
Arto
A
Pakarinen
Travis
T
Triplett-McBride
Jeffrey M
JM
McBride
Arja
A
Häkkinen
Markku
M
Alen
Michael R
MR
McGuigan
Roger
R
Bronks
Robert U
RU
Newton
D000368:Aged; D015444:Exercise / Q000502:physiology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D013006:Growth Hormone / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D006984:Hypertrophy; D008297:Male; D008875:Middle Aged; D018485:Muscle Fibers, Skeletal; D018482:Muscle, Skeletal / Q000473:pathology / Q000502:physiology*
D012739:Gonadal Steroid Hormones; D006728:Hormones; D013006:Growth Hormone