Fluorine-18 FDG-PET in detecting local recurrence and distant metastases in breast cancer--Taiwanese experiences.
Fluorine-18 fluorodeonyglucose positron emission tomography (FDG-PET) was used to detect local recurrence, axillary lymph node (LN) involvement and distant metastases in patients with breast cancer. Thirty-six female patients with breast cancer s/p operation underwent FDG-PET studies. Findings were confirmed by histology following surgery and/or biopsy or negative follow-up results over a period of at least one year. In the evaluation of local recurrence, the diagnostic sensitivity, specificity, and accuracy of FDG-PET was 100, 96.8, and 97.2%, respectively. In the evaluation of axillary LN involvement, sensitivity, specificity, and accuracy was 80, 100, and 97.2%, respectively. In the evaluation of distant metastases, the diagnostic sensitivity, specificity, and accuracy was 83.3, 85.2, and 84.4%, respectively. The FDG-PET is a useful diagnostic tool in detecting local recurrence, axillary LN involvement, and distant metastasis.
Lin
Wan-Yu
WY
Department of Nuclear Medicine, Taichung Veterans General Hospital, Department of Radiological Technology, Chung-Tai College of Medical Technology, Taichung, Taiwan.
Tsai
Shih-Chuan
SC
Cheng
Kai-Yuan
KY
Yen
Ruoh-Fang
RF
Kao
Chia-Hung
CH
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014055:Tomography, Emission-Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18