Relationships between trace element concentrations in human blood and serum.
Trace element interactions can affect the absorption, metabolism, or effects of elements. Also, different elements may derive from the same source. Associations in biological media between element concentrations may indicate such phenomena. A large number of correlations were found between 13 trace elements (Co, Cu, Zn, Se, Rb, Rh, Pd, Cd, W, Pt, Hg, Tl, and Pb) in human blood and/or serum, as investigated in 372 Swedish adolescents. Notably, serum Se correlated with blood Pb and blood Hg and Cu and Zn were correlated to each other in both blood and serum. The elements Pt, Pd and Rh, spread in the environment through use of catalytic converters in cars, were closely correlated in both blood and serum. Apart from the correlations with a probable biological or exposure-related explanation, several other correlations, of yet unknown importance and origin, were found.
Department of Pharmacology and Toxicology, Swedish University of Agricultural Sciences, BMC, P.O. Box 573, SE-751 23 Uppsala, Sweden. ebba.barany@farmtox.slu.se
Ebba
E
Bárány
Ingvar A
IA
Bergdahl
Lars-Eric
LE
Bratteby
Thomas
T
Lundh
Gösta
G
Samuelson
Andrejs
A
Schütz
Staffan
S
Skerfving
Agneta
A
Oskarsson
D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D004784:Environmental Monitoring / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D013058:Mass Spectrometry / Q000379:methods; D013548:Sweden; D014131:Trace Elements / Q000097:blood*
D015415:Biomarkers; D014131:Trace Elements