Cancer of the larynx in non-smoking alcohol drinkers and in non-drinking tobacco smokers.
The separate effect of alcohol and tobacco on laryngeal cancer was analysed in two case-control studies from Italy and Switzerland, comprising 40 non-smoking and 68 non-drinking cases, and 160 non-smoking and 161 non-drinking controls. The multivariate odds ratio was 2.46 for heavy drinkers non-smokers, and 9.38 for current smokers non-drinkers.
Bosetti
C
C
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy. bosetti@marionegri.it
Gallus
S
S
Franceschi
S
S
Levi
F
F
Bertuzzi
M
M
Negri
E
E
Talamini
R
R
La Vecchia
C
C
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000453:epidemiology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D007822:Laryngeal Neoplasms / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology*; D013557:Switzerland / Q000453:epidemiology