Choroidal neovascularization occurring concurrently in myopic eyes of monozygotic twins.
OBJECTIVE
To present young monozygotic twins both of whom developed choroidal neovascularization at the same time.
Monozygotic twins, 22-year-old women, who lived in the same house, developed choroidal neovascularization in the left eye at the same time. The degree of myopia was higher in the left eye (-7.75 and -8.5 dpt in spherical equivalent) than in the right eye (-6.75 and -4.5 dpt) of both patients. The choroidal neovascularization regressed in a different time course and the visual acuity returned to normal in both patients.


CONCLUSIONS
This pair of monozygotic twins suggests that both genetic and environmental factors underlie the development of choroidal neovascularization in myopic eyes.
Matsuo
Toshihiko
T
Department of Ophthalmology, Okayama University Medical School, Okayama City, Japan. matsuot@cc.okayama-u.ac.jp
Seguchi
Jiro
J
Shiraga
Fumio
F
Takesue
Yoshiko
Y
Sakaguchi
Noriko
N
D000328:Adult; D020256:Choroidal Neovascularization / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D004200:Diseases in Twins; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D009216:Myopia / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D014430:Twins, Monozygotic / Q000235:genetics*; D014792:Visual Acuity
D005938:Glucocorticoids; D011239:Prednisolone