Escherichia coli O157 and non-O157 isolates are more susceptible to L-lactate than to D-lactate.
The antimicrobial effect of L-lactate was much greater than that of D-lactate over a range of concentrations for Escherichia coli O157 and non-O157 strains. Despite this, the intracellular pHs and membrane potentials of L-lactate- and D-lactate-treated cells were similar, suggesting that these factors are not involved in the antimicrobial action of L-lactate.
Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom. c.leitch@rri.sari.ac.uk
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McWilliam Leitch
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Stewart
D015169:Colony Count, Microbial; D019453:Escherichia coli O157 / Q000187:drug effects* / Q000502:physiology; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation
D007773:Lactates