Polyhydramnios: a predictor of severe growth impairment in achondroplasia.
The phenotypical characteristics in 20 children with achondroplasia were examined in relation to the occurrence of polyhydramnios. A history of polyhydramnios (9 of 20 cases) was associated with a lower height (SD) (P <.05), more severe shortening of the lower segment and upper limbs (P =.0001), and higher frequency of left-handedness (P =.0081).
Division of Pediatrics, Perrino Hospital, Azienda Ospedaliera A. Di Summa, Clinical Physiology Institute (IFC-CNR), National Research Council of Italy, Lecce Section, Brindisi, Italy.
Giuseppe
G
Latini
Claudio
C
De Felice
Stefano
S
Parrini
Alberto
A
Verrotti
Giovanni
G
Di Maggio
Felice
F
Petraglia
D000130:Achondroplasia / Q000150:complications / Q000175:diagnosis; D000367:Age Factors; D001827:Body Height / Q000502:physiology; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007229:Infant Welfare; D008297:Male; D008429:Maternal Welfare; D010290:Parents; D006831:Polyhydramnios / Q000150:complications / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011247:Pregnancy; D012720:Severity of Illness Index; D013223:Statistics as Topic