Pressure drops in a distensible model of end-to-side anastomosis in systemic-to-pulmonary shunts.
The modified Blalock-Taussig shunt is a surgical procedure used as a palliation to treat complex congenital heart defects. It consists of an interposing prosthetic tube between the innominate/subclavian artery and the right pulmonary artery. Previous experience indicates that the pressure drop across the shunt is affected by the pulmonary pressure at the distal anastomosis combined with the distensibility of the anastomosis. In this study, a computational fluid-structure interaction approach is presented to investigate the haemodynamic behaviour. Steady-state fluid dynamics and structural analyses were carried out using commercial codes based on the finite element method (FIDAP and ABAQUS) coupled by means of a purposely-developed procedure to transfer boundary conditions. Both prosthetic tube and artery walls were characterised by non-linear material properties. Three different pulmonary pressures (2, 5 and 15 mmHg) and two volume flow rates (0.4 and 0.8 l/min) were investigated. Results indicate that the effects of distensibility at the distal anastomosis on the shunt pressure drop are relevant only when the distal anastomosis on the shunt pressure drop are relevant only when the distal anastomosis is not fully distended, which occurs when the pulmonary pressure is lower than 5 mmHg.
Department of Bioengineering and Laboratory of Biological Structure Mechanics-LaBS, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, Italy.
Francesco
F
Migliavacca
Giancarlo
G
Pennati
Elena
E
Di Martino
Gabriele
G
Dubini
Riccardo
R
Pietrabissa
D000465:Algorithms; D000714:Anastomosis, Surgical; D001783:Blood Flow Velocity; D001794:Blood Pressure; D003198:Computer Simulation; D020342:Finite Element Analysis; D006439:Hemodynamics; D008955:Models, Cardiovascular; D017711:Nonlinear Dynamics; D011651:Pulmonary Artery / Q000503:physiopathology* / Q000601:surgery*; D012680:Sensitivity and Specificity; D013314:Stress, Mechanical; D013348:Subclavian Artery / Q000503:physiopathology* / Q000601:surgery*