AIDS-related primary central nervous system lymphoma: prolonged remission associated with highly active antiretroviral therapy.
A 36-year-old HIV-seropositive man developed progressive confusion and unilateral tremor of the hand. His medical history included cryptococcal meningitis and CMV colitis. CT scan revealed a single hyperdense mass with minimal peripheral enhancement at the region of the cerebral peduncle and pons, causing obstructive hydrocephalus. He was treated with ventriculo-peritoneal shunt and cranial radiotherapy. He also received treatment with highly active antiretroviral therapy (HAART). A CD4+ cell count was increased from 2 to 345 cells/mm3. He returned to normal function for about 32 months after treatment.
Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
Verajit
V
Chotmongkol
Montien
M
Pesee
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000628:therapy / Q000821:virology; D006679:HIV Seropositivity / Q000188:drug therapy*; D006801:Humans; D019469:Indinavir / Q000008:administration & dosage; D019259:Lamivudine / Q000008:administration & dosage; D016483:Lymphoma, AIDS-Related / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000628:therapy; D008297:Male; D011859:Radiography; D018119:Stavudine / Q000008:administration & dosage; D017287:Ventriculoperitoneal Shunt
D019259:Lamivudine; D019469:Indinavir; D018119:Stavudine