[Progresses in mouse chromosome engineering].
Mouse chromosome engineering, characterized by deletion and rearrangement of large fragment of chromosome, has been an important method for studying the function of mouse genome on a large scale. The latest progress in mouse chromosome engineering was introduced.
Genetic Laboratory of Development and Diseases, Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
You-Liang
YL
Wang
Xiao
X
Yang
D000818:Animals; D002872:Chromosome Deletion; D002875:Chromosomes; D005818:Genetic Engineering; D019426:Integrases / Q000235:genetics; D051379:Mice / Q000235:genetics*; D009154:Mutation; D014764:Viral Proteins / Q000235:genetics
D014764:Viral Proteins; C045073:Cre recombinase; D019426:Integrases