Shared strategies in gene organization among prokaryotes and eukaryotes.
Although genes in prokaryotes and eukaryotes are transcribed and translated by very different mechanisms, they may be organized in their respective chromosomes in surprisingly similar ways. Here, I examine common modes of maintaining nonrandom gene organization in both prokaryotes and eukaryotes, the different ways these organizations have likely arisen, and classes of organization that may be unique to one group or the other.
Lawrence
Jeffrey G
JG
Department of Biological Sciences, University of Pittsburgh, PA 15260, USA. jlawrenc@pitt.edu
D000818:Animals; D001483:Base Sequence / Q000235:genetics; D005057:Eukaryotic Cells / Q000166:cytology / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000235:genetics*; D005796:Genes / Q000235:genetics*; D005809:Genes, Regulator / Q000235:genetics*; D006801:Humans; D007763:Lac Operon / Q000235:genetics; D005810:Multigene Family / Q000235:genetics*; D011387:Prokaryotic Cells / Q000166:cytology / Q000378:metabolism*; D014176:Protein Biosynthesis / Q000235:genetics