Enantiomeric partitioning using fluorous biphase methodology for lipase-mediated (trans)esterifications.
Lipase-catalysed (trans)esterification reactions in homogenous perfluorocarbon-hydrocarbon solvents enabled direct enantiomeric partitioning (up to 95% ee) of the products by liquid-liquid separation.
School of Chemistry, Centre for Biomolecular Sciences, University of St Andrews, North Haugh, St Andrews, Fife, UK KY16 9ST.
Petr
P
Beier
David
D
O'Hagan
D004951:Esterification; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification*; D005466:Fluorocarbons / Q000737:chemistry; D006838:Hydrocarbons / Q000737:chemistry; D008049:Lipase / Q000378:metabolism*; D012997:Solvents / Q000737:chemistry*; D013237:Stereoisomerism
D004952:Esters; D005466:Fluorocarbons; D006838:Hydrocarbons; D012997:Solvents; D008049:Lipase