An improved assay for genotyping the common Alu insertion in the tissue-type plasminogen activation gene PLAT.
An improved assay for genotyping the common Alu insertion in the tissue-type plasminogen activator (PLAT) locus is described in this report. The assay is a valuable asset to clinical researchers interested in exploring disease associations with this allele. The automation and improved accuracy will facilitate future population-based studies, as well as clinical screening.
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
S M
SM
Sell
T
T
White
P
P
Johnson
J
J
Johnson
E
E
Palmer
C
C
Tullis
P R
PR
Lugemwa
D020087:Alu Elements / Q000235:genetics*; D001331:Automation; D005838:Genotype; D016133:Polymerase Chain Reaction / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000235:genetics*
D010959:Tissue Plasminogen Activator