Treatment with cyclosporin A in a patient with Omenn's syndrome.
Unless treated with haematopoetic stem cell transplantation, Omenn's syndrome, a rare variant of severe combined immunodeficiency, is associated with a fatal outcome. We describe a male infant showing all the typical features of Omenn's syndrome, who was successfully treated with cyclosporin A to improve clinical condition prior to haematopoetic stem cell transplantation.
Department of Pediatrics, Martin-Luther-University, School of Medicine, Halle/Saale, Germany. almut.meyer-bahlburg@medizin.uni-halle.de
A
A
Meyer-Bahlburg
J-P
JP
Haas
R
R
Haase
U
U
Eschrich
A
A
Wawer
L
L
Frank
W Ch
WCh
Marsch
S
S
Burdach
G
G
Horneff
D016572:Cyclosporine / Q000627:therapeutic use*; D003873:Dermatitis, Exfoliative / Q000188:drug therapy*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007231:Infant, Newborn; D008297:Male; D016511:Severe Combined Immunodeficiency / Q000188:drug therapy*; D013577:Syndrome
D003879:Dermatologic Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine