MRI and diffusion MRI in nonparaneoplastic limbic encephalitis.
This paper reports an 65-year-old woman with nonparaneoplastic limbic encephalitis. On MRI and diffusion MRI, diffuse and symmetrical, bilateral high-signal lesions were evident in the medial temporal lobes. The affected areas were hyperintense on b= 1000 s/mm(2) (heavily diffusion-weighted or true diffusion) images, a pattern similar to cytotoxic edema. However, apparent diffusion coefficient (ADC) values read directly from corresponding ADC maps at each temporal lobe were within normal limits: 0.96 and 0.97 x 10 x (-3) mm(2)/s, respectively, excluding cytotoxic edema. The changes were shown to be resolved on a 9-month follow-up MRI.
Department of Radiology, Ege University Hospital, 35100 Bornova, Izmir, Turkey. rnsener@hotmail.com
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D000368:Aged; D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D020363:Limbic Encephalitis / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging