Assessing perfusion and capillary permeability changes induced by a VEGF inhibitor in human tumor xenografts using macromolecular MR imaging contrast media.
Clément
Olivier
O
Laboratoire de Recherche en Imagerie INSERM U 494, Faculté de Médecine Necker-Enfants Malades, University Paris V, France.
Pradel
Clément
C
Siauve
Nathalie
N
Frouin
Frédérique
F
Bruneteau
Gaëlle
G
Kahn
Edmond
E
Frija
Guy
G
Cuénod
Charles-André
CA
D000818:Animals; D002199:Capillary Permeability; D003287:Contrast Media; D016228:Endothelial Growth Factors / Q000276:immunology; D005682:Gadolinium; D006571:Heterocyclic Compounds; D036341:Intercellular Signaling Peptides and Proteins / Q000276:immunology; D008222:Lymphokines / Q000276:immunology; D046911:Macromolecular Substances; D008279:Magnetic Resonance Imaging; D008297:Male; D051379:Mice; D008819:Mice, Nude; D008833:Microcirculation; D009368:Neoplasm Transplantation; D009389:Neovascularization, Pathologic / Q000473:pathology*; D009942:Organometallic Compounds; D010477:Perfusion; D011471:Prostatic Neoplasms / Q000473:pathology*; D011799:Quinazolines / Q000494:pharmacology*; D014183:Transplantation, Heterologous; D014230:Triazoles / Q000494:pharmacology*; D014407:Tumor Cells, Cultured; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D003287:Contrast Media; D016228:Endothelial Growth Factors; D006571:Heterocyclic Compounds; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines; D046911:Macromolecular Substances; D009942:Organometallic Compounds; D011799:Quinazolines; D014230:Triazoles; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; C405268:ZD 4190; D005682:Gadolinium; C435266:contrast agent P792