Epoxidation of some natural furocoumarins and furochromones using gamma-ray.
Epoxidation of imperatorin (1a) with m-chloroperbenzoic acid (mcpba) under the irradiation of gamma-ray gave a mixture of epoxide 3a and dioxofuran 4a. Whereas, alloimperatorin (1b) under the same condition obtained the epoxide 3b as a sole product. On the other hand, it was successfully epoxidized xanthotoxin (1c) with mcpba under the same condition as above. In addition, visnagin (2a) was epoxidized to give a mixture of epoxides 5a, 6a. While, khellin (2b) gave the epoxide 5b, no other products were observed.
Department of Home Economy, Faculty of Specific Education, Mansoura University, Mansoura, Egypt.
E M
EM
Elgendy
A A
AA
Ramadan
W
W
Fadaly
M
M
Hammouda
D002723:Chlorobenzoates / Q000737:chemistry; D002867:Chromones / Q000138:chemical synthesis* / Q000528:radiation effects*; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000528:radiation effects*; D011564:Furocoumarins / Q000138:chemical synthesis* / Q000528:radiation effects*; D005720:Gamma Rays; D007202:Indicators and Reagents
D002723:Chlorobenzoates; D002867:Chromones; D004852:Epoxy Compounds; D011564:Furocoumarins; D007202:Indicators and Reagents; C000433:3-chloroperbenzoic acid