High-yield, low-pressure [18O] water targets of titanium and niobium for F-18 production on MC-17 cyclotrons.
Large volume low-pressure targets were designed for use on the wide-beam Scanditronix MC-17 cyclotron. The design was optimized experimentally by construction of aluminum test targets. Final production targets were constructed of titanium and niobium. The targets tripled the routine production yield of the previous target, giving up to 90 GBq (2.5 Ci) of fluoride and essentially eliminated the need for periodic target maintenance. The final targets represent a considerable improvement. However, they have not performed as well as predicted, indicating that further improvement is possible.
Berridge
Marc S
MS
Departments of Radiology and Chemistry, Case Western Reserve University and University Hospitals of Cleveland, 11100 Euclid Ave, Cleveland, OH 44106, USA. msb5@po.cwru.edu
Voelker
Ken W
KW
Bennington
Bonnie
B