Hyperbaric oxygen therapy in the treatment of orbital gas gangrene.
Clostridial gas gangrene (myonecrosis) is a rapidly progressive, life-threatening infection. The occurrence of clostridial gas gangrene in the orbit is uncommon. We present a case of gas gangrene in the orbit of a child, with Clostridium perfringens isolated from the wound. Our patient was successfully treated with extensive surgical débridement, anti-microbial therapy, and hyperbaric oxygen therapy. Hyperbaric oxygen is established as an adjuvant therapy of clostridial gas gangrene and has been shown to significantly reduce morbidity and mortality. To our knowledge, this is the first reported case of using hyperbaric oxygen therapy in the treatment of orbital gas gangrene.
Fielden
Michael P
MP
Division of Ophthalmology, University of Calgary, Alberta, Canada.
Martinovic
Elaine
E
Ells
Anna L
AL
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D003016:Clostridium perfringens / Q000302:isolation & purification; D003646:Debridement; D005260:Female; D005738:Gas Gangrene / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D009916:Orbital Diseases / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents