Fatal intoxication with omethoate.
A case of suicide with the insecticide omethoate is reported. An 18-year-old apprentice gardener had ingested an unknown amount of omethoate. His body was found in his room lying in the storage space under his bed. The autopsy first showed multiple superficial incisions in the skin of his wrists, furthermore hemorrhagic pulmonary oedema, dilation of the right cardiac ventricle and oedema of the brain. The gastric mucosa was swollen and showed a dark brownish colour. An intensive, chemical-like smell rose from the corpse and organs. Toxicological analysis detected omethoate in cardiac blood (208 micro g/ml), urine (225 micro g/ml) and bile (524 micro g/ml), in the liver (341 micro g/ml) and kidneys (505 micro g/ml). In the gastric content the level was 48223 micro g/ml. The amount of the active AChE in peripheral blood serum was reduced to less than 0.2% of the normal level. To our knowledge no case of a fatal suicide by ingestion of omethoate has been reported in literature.
Institute of Legal Medicine, Leopold-Franzens-University of Innsbruck, Muellerstrasse 44, 6020 Innsbruck. marion.pavlic@uibk.ac.at
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Pavlic
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Haidekker
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Grubwieser
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Rabl
D000110:Acetylcholinesterase / Q000097:blood; D000293:Adolescent; D001317:Austria; D001344:Autopsy; D002800:Cholinesterase Inhibitors / Q000032:analysis / Q000493:pharmacokinetics / Q000506:poisoning*; D002849:Chromatography, Gas; D004117:Dimethoate / Q000031:analogs & derivatives* / Q000032:analysis / Q000493:pharmacokinetics / Q000506:poisoning*; D017809:Fatal Outcome; D006801:Humans; D007306:Insecticides / Q000032:analysis / Q000493:pharmacokinetics / Q000506:poisoning*; D008297:Male; D011041:Poisoning / Q000097:blood; D013405:Suicide; D014018:Tissue Distribution
D002800:Cholinesterase Inhibitors; D007306:Insecticides; C002302:dimethoxon; D000110:Acetylcholinesterase; D004117:Dimethoate