Report of a suicidal digoxin intoxication: a case report.
Digoxin is a cardiotonic glycoside that is primarily used in the treatment of heart failure, atrial fibrillation or flutter, and paroxysmal atrial tachycardia. Intoxication due to digitalis excess is a common problem in clinical practice because it is therapeutically effective within a narrow dose range. However, massive intoxication with digitalis glycosides following a suicidal attempt is a rare event. In this report we describe an overdose fatality involving digoxin in a suicidal 82-year-old man, in whom measurement of serum digoxin concentration is available. A toxicological study of our patient, approximately two and a half hours after ingestion of the drug, revealed digoxin concentrations within 12.2-13.2 ng/ml in the blood, while the mean therapeutic serum concentration ranged from 0.5 to 2 ng/ml.
Rodríguez-Calvo
María S
MS
Institute of Legal Medicine, University of Santiago de Compostela, Spain. apimlsol@usc.es
Rico
Rosa
R
López-Rivadulla
Manuel
M
Suárez-Peñaranda
José M
JM
Muñoz
José I
JI
Concheiro
Luis
L
D000368:Aged; D000369:Aged, 80 and over; D004077:Digoxin / Q000097:blood / Q000506:poisoning*; D005554:Forensic Medicine; D006801:Humans; D008297:Male; D013405:Suicide
D004077:Digoxin