pi-Ligands for generating transition metal-peptide complexes: coordination of amino acid derivatives to tungsten utilizing alkyne ligands.
[structure: see text] Amino acid derivatives bearing an alkyne (AA-CCH) at either the N- or C-terminus readily react with W(CO)3(S2CNMe2)2 to replace the carbon monoxides and form the novel bis-alkyne complexes W(AA-CCH)2(S2CNMe2)2; the solution behavior of these complexes shows that only the alkyne, and not the other functional groups on the amino acid, bonds to the tungsten.
Curran
Timothy P
TP
Department of Chemistry, Trinity College, Hartford, Connecticut 06106-3100, USA. timothy.curan@trincoll.edu
Grant
Arlicia L
AL
Lucht
Rebecca A
RA
Carter
Joi C
JC
Affonso
Jesse
J
D000480:Alkynes / Q000737:chemistry; D006860:Hydrogen Bonding; D007536:Isomerism; D008024:Ligands; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D028561:Transition Elements / Q000737:chemistry; D014414:Tungsten / Q000737:chemistry*
D000480:Alkynes; D008024:Ligands; D009942:Organometallic Compounds; D010455:Peptides; D028561:Transition Elements; D014414:Tungsten