Winterbottom's sign and hypertrophic cardiomyopathy.
We present the case of a patient who presented with hypertrophic cardiomyopathy, generalized lymphadenopathy and serological evidence of African sleeping sickness (Trypanosoma gambiense). He made a full recovery after intravenous administration of eflornithine, a drug that is no longer distributed for antiparasitic indications for pharmacoeconomic reasons.
Stephan
Christoph
C
Zentrum der Inneren Medizin, Klinikum der Johann Wolfgang Goethe Universität, Frankfurt, Germany. StephanC@hivcenter.de
Just-Nuebling
Gudrun
G
Fichtlscherer
Stephan
S
Kriener
Susanne
S
Brodt
Hans-Reinhard
HR
D000328:Adult; D000818:Animals; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications*; D003937:Diagnosis, Differential; D000518:Eflornithine / Q000627:therapeutic use*; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications*; D008297:Male; D014344:Trypanocidal Agents / Q000627:therapeutic use*; D014347:Trypanosoma brucei gambiense; D014353:Trypanosomiasis, African / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D014344:Trypanocidal Agents; D000518:Eflornithine