Non-cardiogenic pulmonary oedema in the course of verapamil intoxication.
Only three cases of non-cardiogenic pulmonary oedema secondary to high dose verapamil ingestion have been described in the literature. This report describes two girls, who developed pulmonary oedema in the course of massive dose verapamil ingestion (total of 6000 mg and 7200 mg). Left ventricule size and function was normal on transthoracic echocardiograms in both of these patients. They were treated successfully with mechanical ventilatory support. The report emphasises that this fatal complication may be seen with verapamil overdose and underlying mechanisms and therapeutic approach are discussed.
Department of Haematology, Farabi Hospital, Karadeniz Technical University, School of Medicine, Trabzon, Turkey. samikarti@yahoo.com
S
S
Sami Karti
H
H
Ulusoy
M
M
Yandi
A
A
Gündüz
M
M
Koşucu
K
K
Erol
S
S
Ratip
D000328:Adult; D062787:Drug Overdose; D005260:Female; D006801:Humans; D011041:Poisoning / Q000150:complications; D011654:Pulmonary Edema / Q000139:chemically induced*; D012121:Respiration, Artificial; D013406:Suicide, Attempted; D014700:Verapamil / Q000506:poisoning*
D014700:Verapamil