Coupled zones of f-actin and microtubule movement in polarized cells.
Interactions between the actin and microtubule cytoskeletons occur during cell polarization. Two papers in a recent issue of the Journal of Cell Biology use fluorescent speckle microscopy (FSM) to analyze the relationship between actin and microtubule movements in migrating epithelial cells and in polarizing neuronal growth cones.
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
Jennifer S
JS
Tirnauer
D000199:Actins / Q000378:metabolism* / Q000648:ultrastructure; D000818:Animals; D002465:Cell Movement / Q000502:physiology*; D016764:Cell Polarity / Q000502:physiology*; D004847:Epithelial Cells / Q000378:metabolism* / Q000648:ultrastructure; D020439:Growth Cones / Q000378:metabolism* / Q000648:ultrastructure; D006801:Humans; D008870:Microtubules / Q000378:metabolism* / Q000648:ultrastructure; D023421:Models, Animal; D011108:Polymers / Q000378:metabolism; D011554:Pseudopodia / Q000378:metabolism / Q000648:ultrastructure
D000199:Actins; D011108:Polymers