[Eradication therapy of Helicobacter pylori for elderly patients in Japan].
In Japan, an eradication therapy of Helicobacter pylori(H. pylori) for peptic ulcers of stomach and duodenum was approved by a health insurance since November 1, 2000. A method of an eradication therapy is as follows. Adult patients are received lansoprazole 30 mg, amoxicillin 750 mg, clarithromycin 200-400 mg at the same time twice daily for seven days. This therapy is based on a guideline of a Japanese association of Helicobacter Research. Many elderly patients have complications such as hypertension, cerebral vascular disturbance, heart failure and so on. Moreover, they often take a several medicine including NSAIDs(non-steroidal anti-inflammatory drugs). Therefore, you should pay attention especially to interaction of drugs when planning an eradication therapy of H. pylori for elderly patients.
Division of Endoscopy, Center for Photomedicine.
Tetsuya
T
Nakamura
Akira
A
Terano
D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000368:Aged; D000658:Amoxicillin / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal; D017291:Clarithromycin / Q000008:administration & dosage; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori; D006801:Humans; D007564:Japan; D064747:Lansoprazole; D009853:Omeprazole / Q000008:administration & dosage / Q000031:analogs & derivatives*; D017410:Practice Guidelines as Topic
D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000894:Anti-Inflammatory Agents, Non-Steroidal; D064747:Lansoprazole; D000658:Amoxicillin; D017291:Clarithromycin; D009853:Omeprazole