Solitary fibrous tumor of the parotid gland: a case report.
The solitary fibrous tumor is traditionally associated with a mesothelial-lined surface. However, any organ with mesenchymal tissue has the potential for developing this tumor; therefore, it has been described in organs not associated with serosal surfaces. We report a case of solitary fibrous tumor of the parotid gland. Microscopically, the tumor showed a patternless arrangement of spindle cells in a fibrotic background and prominent vascular structures of varying size. Tumor cells showed a strong immunoreactivity for CD34 and bcl-2 antigens, but the tissue was negative for antibodies directed against actins, S-100 protein, and cytokeratins. One year after excision, the patient was alive and without evidence of disease.
Guerra
Mario Fernando Muñoz
MF
University Hospital La Princesa, C/General Ricardos n-171, 2-B, 28025-Madrid, Spain. maxmferm@excite.com
Amat
Carlos Gamallo
CG
Campo
Francisco Rodríguez
FR
Pérez
Jesús Sastre
JS
D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018218:Neoplasms, Fibrous Tissue / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D010307:Parotid Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis
D018952:Antigens, CD34; D019253:Proto-Oncogene Proteins c-bcl-2