[Blood flow in ophthalmic artery and visual evoked potentials in diabetic patients].
Diabetes despite the progress in therapy causes various complications including the visual impairment. The evaluation of Visual Evoked Potentials (VEP) gives the possibility to detect subclinical features of visual tract damage whereas Transcranial Doppler Sonography enables non-invasive vessel assessment including Ophthalmic Artery (OA). The assessment of VEP and Blood Flow Velocities (BFV) of carotid and ophthalmic artery in diabetics with various changes in retinal arteries was the purpose of this investigation. 26 diabetics, at the average age of 43.7 +/- 12.1 years and average diabetes treatment duration of 9.4 +/- 4.9 years, and 43 healthy controls were examined. In each patient ophthalmoscopy, doppler examination of carotid and ophthalmic arteries (CCA, ICA, ECA, OA) and evaluation of VEP was performed. BFV of ICA and ECA was significantly greater (p < 0.001) whereas BFV of OA was greater in diabetics in comparison to the controls. VEP latency was significantly prolonged (p < 0.01) in diabetic patients compared to control group. BFV of ICA and OA in retinopathy patients was significantly lower comparing to angiopathy patients (p < or = 0.02; p < or = 0.01 respectively) whereas VEP amplitude was similar in examined subgroups of diabetics. The correlation between BFV of OA and VEP latency was not observed in diabetics. The obtained results suggest that diabetes affects negatively blood flow velocities of important for visual organ vessels as well as visual tract conduction.
Pierzchała
Krystyna
K
Katedry i Kliniki Neurologii w Zabrzu.
Kwieciński
Janusz
J
D000328:Adult; D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000503:physiopathology; D016022:Case-Control Studies; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003930:Diabetic Retinopathy / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012161:Retinal Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017585:Ultrasonography, Doppler, Transcranial