[Evaluation of serum levels of tick-borne encephalitis (TBE) virus antibodies after administration of FSME inject vaccine].
OBJECTIVE
The purpose of this work was to evaluate the changes of anti-TBE virus antibodies serum concentration 3 months after administration of FSME Inject vaccine.


METHODS
The detection of IgG antibodies against TBE virus was performed in sera of 106 forest workers aged mean = 41.5. These sera were examined twice before and after vaccine administration using FSME Kombi-Kit. According to producer's information the "safe" concentration, which protects from TBE virus infection, is over 11VE.


RESULTS
In examination 126 (24.5%) sera showed concentration of examined antibodies lower than 11 VE but in 80 (75.5%) sera antibodies concentration was from 12 to 47 VE (mean = 24.15 VE). In the examination 2 significant increase of antibodies concentration was stated. In all sera the concentration ranged from 9 to 62 VE (mean = 39.83 VE).


CONCLUSIONS
The administration of TBE vaccine booster causes quick increase of antibodies against TBE virus to the level which is considered to be protective against TBE virus infection.
Pancewicz
Sławomir A
SA
Klinika Chorób Zakaźnych i Neuroinfekcji AM w Białymstoku.
Hermanowska-Szpakowicz
Teresa
T
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D004675:Encephalitis, Tick-Borne / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000276:immunology / Q000517:prevention & control; D011044:Poland / Q000453:epidemiology; D014765:Viral Vaccines / Q000276:immunology
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D014765:Viral Vaccines