Lanthanide Lewis acid-mediated enantioselective conjugate radical additions.
[reaction: see text] Lanthanide triflates along with proline-derived ligands have been found to be efficient catalysts for enantioselective conjugate addition of nucleophilic radicals to enoates. N-Acyl oxazolidinones, when used as achiral additives, gave meaningful enhancements in the ees for the product.
Sibi
Mukund P
MP
Department of Chemistry, North Dakota State University, Fargo, North Dakota 58105, USA. mukund.sibi@ndsu.nodak.edu
Manyem
Shankar
S
D000475:Alkenes / Q000737:chemistry; D002384:Catalysis; D005609:Free Radicals / Q000737:chemistry*; D007811:Lanthanum / Q000737:chemistry*; D008024:Ligands; D011392:Proline / Q000737:chemistry; D013237:Stereoisomerism
D000475:Alkenes; D005609:Free Radicals; D008024:Ligands; D007811:Lanthanum; D011392:Proline