[Current strategies in peripheral nerve repair].
The paper presents main research trends focused on peripheral nerves regeneration. Modern surgery techniques in humans require dissection of the nerve bridges, leading to extra mutilation of a patient. The recovery of motor and sensory functions is also unsatisfactory. Therefore scientists are looking for new materials and techniques capable of replacing injured nerve trunks as well as of improving the reinnervation of target tissues. In this kind of experiments chambers joining proximal and distal stumps of transected peripheral nerve are very useful. Such chambers may also contain growth-promoting factors or glial cells supporting the regrowth. Progress in molecular biology and biomaterials engineering will be probably the most critical step to therapeutic intervention in nerve regeneration.
fzjkatpl@infomed.slam.katowice.pl
Joanna
J
Lewin-Kowalik
D006801:Humans; D009416:Nerve Regeneration; D009473:Neuronal Plasticity; D010525:Peripheral Nerves / Q000503:physiopathology / Q000601:surgery; D020127:Recovery of Function