[Sensibility and specificity of cytology and colposcopy exams with the histological evaluation of cervical intraepithelial lesions].
OBJECTIVE
To evaluate the correlation of cytopathological and colposcopycal diagnosis with the histopathological analysis from biopsy.


METHODS
80 patients from the colposcopy ambulatory of the Hospital e Maternidade Santa Brígida de Curitiba, PR, were selected. Those patients were sent to colposcopy under the following criteria: 1) previous abnormal cytopathological exams, 2) Indicative clinical data or, 3) Suspected lesions on gynecological exam. The statistical significance analysis of the results was done using the chi-square test. Sensibility, specificity, positive predictive value (PPV) and negative predictive value (NPV) were also determined.


RESULTS
The patients' mean age was 30.2 (+/-10.9). Cytopathological capability of identifying lesions was 50% when compared to histology. Its specificity was 77%, the sensibility 41%, the PPV 74%, and the NPV 45%. Colposcopy capability of identifying lesions was 50%. Its sensibility, specificity, PPV and NPV were 96%, 19%, 65% and 75% respectively. The two methods associated were capable of identifying 63% of the lesions.


CONCLUSIONS
Cytopathology was a high specificity exam, while colposcopy from those selected patients had a high sensibility. Colposcopy association with cytopathological screening, on those selected patients, significantly raises the diagnostic accuracy of cervical cancer precursor lesions.
Serviço de Patologia do Trato Genital Inferior e Colposcopia, Hospital e Maternidade Santa Brígida.
Felipe Francisco Bondan
FF
Tuon
Marcio Sommer
MS
Bittencourt
Maria Alice
MA
Panichi
Alvaro Piazetta
AP
Pinto
D000293:Adolescent; D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D003127:Colposcopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D002577:Uterine Cervical Diseases / Q000175:diagnosis* / Q000473:pathology; D014626:Vaginal Smears