Effect of Weissella confusa strain PL9001 on the adherence and growth of Helicobacter pylori.
Viable and nonviable Weissella confusa strain PL9001 inhibited the binding of Helicobacter pylori to human gastric-cell line MKN-45 cells by more than 90%. Spent culture supernatant of PL9001 rapidly decreased the viability of H. pylori, rupturing cell walls. The results suggest that PL9001 is a probiotic that can reduce the infectivity and persistence of H. pylori.
Department of Biotechnology, Seoul Women's University, Seoul 139-774, Korea.
Hyeran
H
Nam
Misun
M
Ha
On
O
Bae
Yeonhee
Y
Lee
D000898:Antibiosis; D001422:Bacterial Adhesion / Q000502:physiology*; D002478:Cells, Cultured; D006094:Gram-Positive Bacteria / Q000502:physiology*; D016480:Helicobacter pylori / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D019936:Probiotics / Q000494:pharmacology*; D013270:Stomach / Q000166:cytology