Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition?
Center for Pharmaceutical and Molecular Imaging, Department of Radiology, University of California, San Francisco, USA.
Robert C
RC
Brasch
Axel
A
Gossmann
Thomas H
TH
Helbich
Nagato
N
Kuriyama
Timothy P L
TP
Roberts
David M
DM
Shames
N
N
van Bruggen
Michael F
MF
Wendland
Mark A
MA
Israel
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D001932:Brain Neoplasms / Q000098:blood supply* / Q000473:pathology; D002199:Capillary Permeability; D003287:Contrast Media; D016228:Endothelial Growth Factors / Q000276:immunology; D005682:Gadolinium; D005910:Glioma / Q000098:blood supply* / Q000473:pathology; D036341:Intercellular Signaling Peptides and Proteins / Q000276:immunology; D008222:Lymphokines / Q000276:immunology; D008279:Magnetic Resonance Imaging; D008833:Microcirculation; D009389:Neovascularization, Pathologic / Q000473:pathology*; D051381:Rats; D011923:Rats, Nude; D014407:Tumor Cells, Cultured; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D000911:Antibodies, Monoclonal; D003287:Contrast Media; D016228:Endothelial Growth Factors; D036341:Intercellular Signaling Peptides and Proteins; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D005682:Gadolinium