Methemoglobinemia in an infant receiving nitric oxide after the use of eutectic mixture of local anesthetic.
High levels of methemoglobinemia can cause tissue hypoxia and cyanosis. We report the case of a 7-month-old girl with pulmonary dysplasia receiving inhaled nitric oxide who had cyanosis caused by methemoglobinemia after prolonged use of a eutectic mixture of local anesthetics cream.
Miami Children's Hospital, Division of Neonatal Neurology, Department of Neurology, University of Miami School of Medicine, Miami, Florida, USA.
Scarlett
S
Sinisterra
Elena
E
Miravet
Israel
I
Alfonso
Amed
A
Soliz
Oscar
O
Papazian
D000280:Administration, Inhalation; D019162:Anesthetics, Combined / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007223:Infant; D008012:Lidocaine / Q000009:adverse effects*; D000077442:Lidocaine, Prilocaine Drug Combination; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000188:drug therapy*; D009569:Nitric Oxide / Q000627:therapeutic use*; D011318:Prilocaine / Q000009:adverse effects*; D017211:Treatment Failure
D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D000077442:Lidocaine, Prilocaine Drug Combination; D011318:Prilocaine; D009569:Nitric Oxide; D008012:Lidocaine