pi-Ligands for generating transition metal-peptide complexes: coordination of amino acid derivatives to tungsten utilizing alkyne ligands.
[structure: see text] Amino acid derivatives bearing an alkyne (AA-CCH) at either the N- or C-terminus readily react with W(CO)3(S2CNMe2)2 to replace the carbon monoxides and form the novel bis-alkyne complexes W(AA-CCH)2(S2CNMe2)2; the solution behavior of these complexes shows that only the alkyne, and not the other functional groups on the amino acid, bonds to the tungsten.
Department of Chemistry, Trinity College, Hartford, Connecticut 06106-3100, USA. timothy.curan@trincoll.edu
Timothy P
TP
Curran
Arlicia L
AL
Grant
Rebecca A
RA
Lucht
Joi C
JC
Carter
Jesse
J
Affonso
D000480:Alkynes / Q000737:chemistry; D006860:Hydrogen Bonding; D007536:Isomerism; D008024:Ligands; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D028561:Transition Elements / Q000737:chemistry; D014414:Tungsten / Q000737:chemistry*
D000480:Alkynes; D008024:Ligands; D009942:Organometallic Compounds; D010455:Peptides; D028561:Transition Elements; D014414:Tungsten