Cerebral aspergillosis caused by Neosartorya hiratsukae, Brazil.
We report the first case of infection by Neosartorya hiratsukae, an ascomycete in which the conidial state resembles Aspergillus fumigatus. The fungus caused a brain infection in a Brazilian woman, who died despite itraconazole treatment. Diagnosis was established by direct microscopic examination, computed tomographic scan, and magnetic resonance imaging of the brain, and repeated cultures from the lesions. The in vitro antifungal susceptibility of the isolate is provided.
Unitat de Microbiologia, Depatment de Ciències Mèdiques Bàsiques, Facultat de Medicina i Ciènies de la Salut, Universitat Rovia i Virgili, Reus, Tarragona, Spain. umb@fmcs.vrv.es
Josep
J
Guarro
Esper G
EG
Kallas
Patricio
P
Godoy
Anna
A
Karenina
Josepa
J
Gené
Alberto
A
Stchigel
Arnaldo Lopes
AL
Colombo
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis; D001938:Brazil; D002494:Central Nervous System Infections / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005658:Fungi / Q000145:classification* / Q000302:isolation & purification* / Q000472:pathogenicity; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B