[Prostatic exfoliative cytology obtained from urine samples after massage. Initial results].
BACKGROUND
The same as the exfoliative cytology is a routine method to diagnose bladder tumour, the prostatic cytology obtained after massage may become a useful procedure to diagnose prostate cancer.


OBJECTIVE
To obtain suitable prostatic cytologic material. To establish the role of the exfoliative cytology to diagnose cancer.


METHODS
We made a prospective longitudinal descriptive study with 60 patients out of 150 (all of them with possible prostate cancer) for two years. We compared cytologic discoveries (urine after massage) with histological parameters (biopsies).


RESULTS
When the cytology fulfills a series of requirements (a high number of prostatic cells, anisokariosis and antibodies Ki-67+) and these are compared with the histological data, we obtained a specificity of 100% and a sensibility of 67% for prostatic cancer. With this information the cytology reaches a predictive value of 100% and negative of 92%.


CONCLUSIONS
It is possible to obtain prostatic cytologic material in a simple and easy way. The prostatic cytology may become a valid and useful method to diagnose the carcinoma of the prostate. Also this material can be used for multiple diagnostic, follow-up and research procedures.
Varo Solís
C
C
Departamento de Cirugía, Servicio de Urología, Hospital Universitario de Puerto Real, Cádiz.
Hens Pérez
A
A
Bachiller Burgos
J
J
Figueroa Murillo
E
E
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D002467:Cell Nucleus / Q000648:ultrastructure; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D008137:Longitudinal Studies; D008297:Male; D008405:Massage; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011467:Prostate / Q000166:cytology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D011472:Prostatitis / Q000175:diagnosis / Q000473:pathology; D012680:Sensitivity and Specificity; D014556:Urine / Q000166:cytology*
D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D017430:Prostate-Specific Antigen