Dementia with Lewy bodies: a diagnostic and treatment challenge.
DLB demonstrates the pathological overlap between neurodegenerative disorders. Clinicians who work with the elderly need to be aware of the dramatic variability of symptoms in order to make an accurate diagnosis and treatment plan. There is much work to be done on the genetics and pathogenesis of DLB. More objectives diagnostic tests are needed, as are more controlled treatment trials for the specific symptoms of DLB.
Brown Medical School, Butler Hospital, Providence, RI, USA. Stephen_Salloway@brown.edu
Stephen
S
Salloway
Stephen
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Correia
Jason
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Peck
Colin
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Harrington
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000628:therapy; D000818:Animals; D001921:Brain / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D020961:Lewy Body Disease / Q000175:diagnosis* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D019636:Neurodegenerative Diseases / Q000175:diagnosis / Q000628:therapy; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000175:diagnosis* / Q000628:therapy; D011379:Prognosis; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed