Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity.
Tukey
Robert H
RH
Department of Pharmacology, Chemistry & Biochemistry, University of California, San Diego, La Jolla, California 92093, USA. rturkey@ucsd.edu
Strassburg
Christian P
CP
Mackenzie
Peter I
PI
D000972:Antineoplastic Agents, Phytogenic / Q000633:toxicity*; D002166:Camptothecin / Q000031:analogs & derivatives / Q000633:toxicity*; D004347:Drug Interactions; D004789:Enzyme Activation / Q000187:drug effects; D005419:Flavonoids / Q000494:pharmacology; D014453:Glucuronosyltransferase / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D000077146:Irinotecan; D010597:Pharmacogenetics; D000099148:UGT1A1 Enzyme
D000972:Antineoplastic Agents, Phytogenic; D002166:Camptothecin; D005419:Flavonoids; D014453:Glucuronosyltransferase; D000077146:Irinotecan; D000099148:UGT1A1 Enzyme