[Synaptic plasticity in the motor cortex].
Horizontally-oriented intracortical connections have been proposed to serve as a substrate for plastic reorganizations of adult motor cortex. N-methyl-D-aspartate (NMDA) receptor-dependent long-term potentiation (LTP) of synaptic efficacy is a candidate mechanism of these reorganizations in mammalian species ranging from rats to humans. The acquisition of a motor skill is accompanied by increased strength of synaptic connections within adult rat primary motor cortex, most likely due to LTP-like mechanisms.
Instytut Farmakologii PAN w Krakowie.
Grzegorz
G
Hess
D000818:Animals; D006624:Hippocampus / Q000502:physiology; D006801:Humans; D017774:Long-Term Potentiation / Q000502:physiology*; D008568:Memory / Q000502:physiology; D009044:Motor Cortex / Q000502:physiology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D013569:Synapses / Q000502:physiology*
D016194:Receptors, N-Methyl-D-Aspartate