Sensitivity enhancement in multiple-quantum NMR experiments with CPMG detection.
We present a modified multiple-quantum (MQ) experiment, which implements the Carr-Purcell-Meiboom-Gill (CPMG) detection scheme in the static MQ NMR experiment proposed by W. S. Warren et al. (1980, J. Chem. Phys.73, 2084-2099) and exploited further by O. N. Antzutkin and R. Tycko (1999, J. Chem. Phys.110, 2749-2752). It is demonstrated that a significant enhancement in the sensitivity can be achieved by acquiring echo trains in the MQ experiments for static powder samples. The modified scheme employing the CPMG detection was superior to the original MQ experiment, in particular for the carbonyl carbon with a very large chemical shift anisotropy.
Lim
Kwang Hun
KH
Department of Chemistry, University of California at Berkley, California 94720, USA.
Nguyen
Tuan
T
Mazur
Tanya
T
Wemmer
David E
DE
Pines
Alexander
A
D016880:Anisotropy; D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
D002247:Carbon Isotopes