Not yet time to change the guidelines for monitoring methotrexate liver toxicity: they have served us well.
Kremer
Joel M
JM
D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000188:drug therapy*; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000517:prevention & control; D016903:Drug Monitoring; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects*; D017410:Practice Guidelines as Topic; D012219:Rheumatology / Q000379:methods* / Q000639:trends
D018501:Antirheumatic Agents; D001219:Aspartate Aminotransferases; D008727:Methotrexate