Membrane array technology for drug discovery.
Lipid membrane arrays are a new technology emerging at the interface of materials science and cell biology. A defining feature of the membrane array architecture is the naturally fluid and functional state of the lipid bilayer membrane, which is maintained in an array of discrete corrals on a solid substrate. Solid-supported membrane arrays are beginning to find important applications in academic research. Recent developments in membrane array manufacturing are positioning this technology to make the transition into industrial drug discovery programs.
University of California, Department of Chemistry, Berkeley, CA 94720, USA. JTGroves@Ibl.gov
Jay T
JT
Groves
D000818:Animals; D006801:Humans; D008051:Lipid Bilayers / Q000737:chemistry; D008567:Membranes, Artificial; D040081:Protein Array Analysis / Q000379:methods / Q000639:trends; D013678:Technology, Pharmaceutical / Q000379:methods* / Q000639:trends
D008051:Lipid Bilayers; D008567:Membranes, Artificial