Correlation of cystoscopy with histology of recurrent papillary tumors of the bladder.
OBJECTIVE
We correlated individual urologist impressions of tumor stage and grade of recurrent papillary bladder tumors at cystoscopy with histological findings after transurethral resection to determine whether cystoscopy can reliably identify low grade, noninvasive papillary tumor for outpatient fulguration.


METHODS
A total of 144 recurrent papillary bladder tumors identified on outpatient flexible cystoscopy were classified as low grade and noninvasive (stage Ta grade 1), high grade and noninvasive (stage Ta grade 3) or invasive (stage T1). Voided urine cytology was also performed. The cystoscopic impression of each tumor was correlated with the final histological findings of tumor stage and grade after transurethral resection.


RESULTS
Cystoscopy classified 97 tumors as stage Ta grade 1 and 47 as stage Ta grade 3 or stage T1. Cystoscopy correctly predicted the tumor stage and grade of 93% of stage Ta grade 1 and 99% of stage Ta grade 1 lesions associated with negative urine cytology.


CONCLUSIONS
Urologists can usually identify noninvasive, low grade recurrent papillary tumors on followup cystoscopy that may be treated safely with outpatient fulguration.
Department of Urology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Harry W
HW
Herr
S Machele
SM
Donat
Guido
G
Dalbagni
D002291:Carcinoma, Papillary / Q000473:pathology*; D003558:Cystoscopy; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D001749:Urinary Bladder Neoplasms / Q000473:pathology*