[Sensibility and specificity of cytology and colposcopy exams with the histological evaluation of cervical intraepithelial lesions].
OBJECTIVE
To evaluate the correlation of cytopathological and colposcopycal diagnosis with the histopathological analysis from biopsy.


METHODS
80 patients from the colposcopy ambulatory of the Hospital e Maternidade Santa Brígida de Curitiba, PR, were selected. Those patients were sent to colposcopy under the following criteria: 1) previous abnormal cytopathological exams, 2) Indicative clinical data or, 3) Suspected lesions on gynecological exam. The statistical significance analysis of the results was done using the chi-square test. Sensibility, specificity, positive predictive value (PPV) and negative predictive value (NPV) were also determined.


RESULTS
The patients' mean age was 30.2 (+/-10.9). Cytopathological capability of identifying lesions was 50% when compared to histology. Its specificity was 77%, the sensibility 41%, the PPV 74%, and the NPV 45%. Colposcopy capability of identifying lesions was 50%. Its sensibility, specificity, PPV and NPV were 96%, 19%, 65% and 75% respectively. The two methods associated were capable of identifying 63% of the lesions.


CONCLUSIONS
Cytopathology was a high specificity exam, while colposcopy from those selected patients had a high sensibility. Colposcopy association with cytopathological screening, on those selected patients, significantly raises the diagnostic accuracy of cervical cancer precursor lesions.
Tuon
Felipe Francisco Bondan
FF
Serviço de Patologia do Trato Genital Inferior e Colposcopia, Hospital e Maternidade Santa Brígida.
Bittencourt
Marcio Sommer
MS
Panichi
Maria Alice
MA
Pinto
Alvaro Piazetta
AP
D000293:Adolescent; D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D003127:Colposcopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D002577:Uterine Cervical Diseases / Q000175:diagnosis* / Q000473:pathology; D014626:Vaginal Smears