[The realm of mitochondrial genetics competence].
The paper discusses the main applications of achievements of mitochondrial genetics: human pathology (mitochondrial diseases, complex disease susceptibility genes) and population genetics (evolution of mankind, demographic history, and migration ways of populations). Awareness of the physiological properties of the well-known nucleotide sequences of mitochondrial DNA is ascertained to be a strategy for studying the functional organization of nuclear genome whose structure is all but completely decoded.
Puzyrev
V P
VP
Golubenko
M V
MV
Freĭdin
M B
MB
D020022:Genetic Predisposition to Disease; D005828:Genetics, Population / Q000639:trends; D016678:Genome; D006801:Humans; D008928:Mitochondria / Q000235:genetics*; D028361:Mitochondrial Diseases / Q000235:genetics / Q000473:pathology; D020412:Multifactorial Inheritance