title: Angiocentric immunoproliferative lesion of the lung.
abstract: Angiocentric immunoproliferative lesion (AIL) is the angiocentric and angiodestructive process of lymphoreticular cells with vascular invasion. AIL of the lung is rare. We treated a 57-year-old woman with AIL of the lung in whom chest radiography and computed tomography showed ground-glass opacity in the left lower lobe and lingular segment. Since macroscopical and intraoperative lung biopsy findings could not rule out the possibility of malignancy, including malignant lymphoma, we conducted left pneumonectomy. Immunohistological examination of the tumor showed that infiltrating lymphocytes consistent with AIL. Because tumor markers such as serum LDH and soluble IL-2 receptor increased postoperatively, we conducted systemic chemotherapy, after which elevated serum tumor markers decreased.
authors.affiliation: Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Ichiki
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Osaki
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Yamashita
authors.forename: Tsunehiro
authors.initials: T
authors.lastname: Oyama
authors.forename: Kenji
authors.initials: K
authors.lastname: Sugio
authors.forename: Kosei
authors.initials: K
authors.lastname: Yasumoto
mesh_terms: D005260:Female; D006801:Humans; D007160:Immunoproliferative Disorders / Q000473:pathology* / Q000628:therapy; D008171:Lung Diseases / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged