Multiple hypoechoic hepatic lesions in a patient with Gaucher disease.
The most common symptoms of Gaucher disease include hepatosplenomegaly and anemia and thrombocytopenia due to hypersplenism. We describe the case of a patient with Gaucher disease who had cachexia, massive hepatomegaly, and multiple focal hepatic lesions. The clinical and radiologic findings suggested malignancy. A biopsy specimen was taken from a hepatic lesion and revealed infiltration by Gaucher cells. We discuss our findings in light of the putative increased incidence of hematologic malignancies in patients with Gaucher disease.
Patlas
Michael
M
Department of Radiology, Shaare Zedek Medical Center, Jerusalem, Israel.
Hadas-Halpern
Irith
I
Reinus
Constantin
C
Zimran
Ari
A
Elstein
Deborah
D
D000328:Adult; D005260:Female; D005776:Gaucher Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology; D008107:Liver Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography