Reemergence of activation with poststroke somatosensory recovery: a serial fMRI case study.
The authors demonstrate the potential for poststroke return of activation in regions normally involved in touch discrimination in a serial, whole-brain fMRI study of a patient with marked sensory loss followed by good recovery. A return of activation in ipsilesional primary and bilateral secondary somatosensory cortices was observed at 3 months after stroke and was maintained at 6 months, indicating a reemergence of activation after the interval of somatosensory recovery. There was little evidence of neural plastic changes early after stroke (2 weeks), when sensory loss was severe.
Carey
L M
LM
National Stroke Research Institute, Austin and Repatriation Medical Centre, Heidelberg West, Australia. L.Carey@austin.unimelb.edu.au
Abbott
D F
DF
Puce
A
A
Jackson
G D
GD
Syngeniotis
A
A
Donnan
G A
GA
D000328:Adult; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009473:Neuronal Plasticity; D020127:Recovery of Function; D013003:Somatosensory Cortex / Q000502:physiology*; D020521:Stroke / Q000473:pathology* / Q000503:physiopathology*; D014110:Touch