[Effects of traffic-generated ultrafine particles on health].
Epidemiological studies have consistently shown relation between exposure to particulate matter in urban air and cardiovascular and pulmonary morbidity and mortality. Some recent population studies suggest that the ultrafine fraction of particulate matter generated by motorised vehicles is particularly damaging. Animal studies and cell culture experiments support this hypothesis and address the possible mechanisms of action. Inhalation of particulate matter, especially ultrafine particles, causes oxidative stress and inflammation in lung tissue, which affects the lung cells per se, as well as the cardiovascular system.
Vrang
Marie-Louise
ML
Afdeling for Miljø- og Arbejdsmedicin, Institut for Folkesundhedsvidenskab, Københavns Universitet, Blegdamsvej 3, DK-2200 København N.
Hertel
Ole
O
Palmgren
Finn
F
Wåhlin
Peter
P
Raaschou-Nielsen
Ole
O
Loft
Steffen H
SH
D000393:Air Pollutants / Q000009:adverse effects*; D000818:Animals; D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality*; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000401:mortality*; D010316:Particle Size; D011014:Pneumonia / Q000209:etiology / Q000401:mortality; D012307:Risk Factors; D001335:Vehicle Emissions / Q000009:adverse effects*
D000393:Air Pollutants; D001335:Vehicle Emissions