Structure of a novel diterpenoid ester, fritillahupehin from bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia.
A new diterpenoid ester, fritillahupehin (1) together with three known fatty acids: palmitic acid (2), lignoceric acid (3) and azelaic acid (4) were isolated from the bulbs of Fritillaria hupehensis Hsiao and K.C. Hsia. The structure of fritillahupehin has been established to be ent-kauran-16beta-yl lignocerate by means of spectroscopic and chemical evidence. Compounds 2-4 were isolated from Fritillaria sp. for the first time.
Ruan
Hanli
H
Faculty of Pharmaceutical Sciences, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, PR China. ruanhl@27.net
Zhang
Yonghui
Y
Wu
Jizhou
J
Deng
Shukai
S
Sun
Handong
H
Fujita
Tetsuro
T
D003998:Dicarboxylic Acids / Q000737:chemistry; D004224:Diterpenes / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry*; D006801:Humans; D019668:Liliaceae; D019308:Palmitic Acid / Q000737:chemistry; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry*
D003998:Dicarboxylic Acids; D004224:Diterpenes; D005227:Fatty Acids; D010936:Plant Extracts; D019308:Palmitic Acid; C010038:azelaic acid; C010210:lignoceric acid