title: Radioguided surgery in primary hyperparathyroidism.
abstract: Surgical neck exploration is usually made in primary hyperparathyroidism (PHPT). Localization of the adenoma or detection of hyperplasia may reduce the operation period and limit the extent of the surgery. In this study the effficacy of preoperative Tc-99m MIBI scintigraphy and intraoperative gamma probe was evaluated.
  
  
  METHODS
  Six patients with PHPT had preoperative Tc-99m MIBI parathyroid scintigraphy and intraoperative gamma probe (IGP) was used in surgical neck exploration.
  
  
  RESULTS
  Parathyroid adenoma was observed in 2/6 patients on scintigraphy in the right retroclavicular region and the left lobe of the thyroid. Both of them were clearly detected by IGP during the surgery and easily removed by the surgeon in a short time (35 min) with a small incision. Pathologic examination confirmed the parathyroid adenoma. No abnormal MIBI uptake was not observed in scintigraphy in 4/6 patients. Subtotal parathyroidectomy was performed in these patients.
  
  
  CONCLUSIONS
  Preoperative Tc-99m MIBI scintigraphy and the use of IGP may limit the exploration and also the operation time and reduce surgical complications.
authors.affiliation: Department of Nuclear Medicine, Ankara University Medical Faculty, Turkey. kucukozlem68@yahoo.com
authors.forename: N O
authors.initials: NO
authors.lastname: Küçük
authors.forename: P
authors.initials: P
authors.lastname: Arican
authors.forename: S
authors.initials: S
authors.lastname: Koçak
authors.forename: G
authors.initials: G
authors.lastname: Aras
mesh_terms: D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery*; D000328:Adult; D005260:Female; D015902:Gamma Cameras; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D007430:Intraoperative Care / Q000379:methods; D007432:Intraoperative Period / Q000379:methods; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery*; D011786:Quality Control; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi