The value of electron microscopy in the diagnosis of IgA nephropathy.
Electron microscopy plays a fundamental role in the evaluation of renal diseases in general. IgA nephropathy represents a heterogeneous disease clinically and morphologically. There are a number of conditions that need to be considered in the differential diagnosis of IgA nephropathy. The renal pathologist must wisely integrate the light microscopic, immunofluorescence, and ultrastructural data when evaluating cases in which IgA nephropathy is a consideration. Electron microscopy can be crucial in providing information either to support a diagnosis of IgA nephropathy or to aid in the diagnosis of one of its mimics.
Gu
Xin
X
Department of Pathology, Louisiana State University Health Sciences Center-Shreveport, Shreveport Louisiana 71130, USA.
Herrera
Guillermo A
GA
D000936:Antigen-Antibody Complex / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005455:Fluorescent Antibody Technique; D005922:Glomerulonephritis, IGA / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007668:Kidney / Q000648:ultrastructure*; D008854:Microscopy, Electron; D011379:Prognosis
D000936:Antigen-Antibody Complex