title: [Psychiatric manifestations of systemic sclerosis].
abstract: Systemic sclerosis (SSc) is a rare conjuctive tissue disorder that is characterized by fibrosis of the skin and internal organs as well as vascular obliteration phenomenons. SSc is responsible for increased morbidity and mortality, and skin fibrosis may be responsible for major body changes. These phenomenons may contribute to the occurrence of psychological disturbances such as anxiety and depression, whereas the incidence of psychotic symptoms is very low in SSc patients. However, the prevalence of psychiatric symptoms during the course of SSc has not been evaluated yet with standardized evaluation scales, and an important breakthrough can be made in understanding the underlying mechanisms of psychiatric manifestations, in order to improve therapeutic management and quality of life.
authors.affiliation: Service de Psychopathologie de l'Enfant, de l'Adolescent, et de Psychiatrie Générale, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris et Université Paris Nord, 125, route de Stalingrad, 93009 Bobigny.
authors.forename: Thierry
authors.initials: T
authors.lastname: Baubet
authors.forename: Marc
authors.initials: M
authors.lastname: Brunet
authors.forename: Paloma
authors.initials: P
authors.lastname: Garcia De La Peña-Lefebvre
authors.forename: Olivier
authors.initials: O
authors.lastname: Taïeb
authors.forename: Marie-Rose
authors.initials: MR
authors.lastname: Moro
authors.forename: Loïc
authors.initials: L
authors.lastname: Guillevin
authors.forename: Luc
authors.initials: L
authors.lastname: Mouthon
mesh_terms: D000223:Adaptation, Psychological; D001007:Anxiety / Q000209:etiology*; D003863:Depression / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D015994:Incidence; D010554:Personality Disorders / Q000209:etiology*; D015995:Prevalence; D011788:Quality of Life; D012595:Scleroderma, Systemic / Q000150:complications* / Q000523:psychology*