title: Highly enantioselective photocyclization of 1-alkyl-2-pyridones to beta-lactams in inclusion crystals with optically active host compounds.
abstract: [reaction: see text] Upon photoirradiation of a 1:1 inclusion complex of (-)-3 and 2-alkyl-1-pyridone (1) (R = Et, n-Pr, i-Pr, n-Bu, i-Bu) in the solid state, optically active beta-lactams (2) of 91-99.5% ee were obtained in good yield.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Ehime University, Matsuyama, Japan. tanaka@en3.ehime-u.ac.jp
authors.forename: Koichi
authors.initials: K
authors.lastname: Tanaka
authors.forename: Takashi
authors.initials: T
authors.lastname: Fujiwara
authors.forename: Zofia
authors.initials: Z
authors.lastname: Urbanczyk-Lipkowska