title: A case of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease) with dystrophic calcinosis cutis and retinal lesions.
abstract: A 65-year-old Japanese female developed a nodule on the distal interphalangealjoint of her right thumb. She also had multiple telangiectasias on her face, oral mucosa, tongue, nasal mucosa and upper extremities. A lip biopsy showed irregularly dilated capillaries and venules lined by flat endothelial cells. The nodule in the right thumb was resected. Histopathology revealed calcium deposits in the dermis. This case was diagnosed as dystrophic calcinosis cutis within hereditary hemorrhagic telangiectasia. Ophthalmologic examination showed bilateral retinal vascular lesions with dilated and tortuous retinal venules.
authors.affiliation: Division of Dermatology, Sagamihara-kyodo Hospital, Sagamihara-shi, Japan.
authors.forename: Hideto
authors.initials: H
authors.lastname: Takahama
authors.forename: Shigemitsu
authors.initials: S
authors.lastname: Noto
authors.forename: Masaru
authors.initials: M
authors.lastname: Ito
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nishimoto
authors.forename: Mamoru
authors.initials: M
authors.lastname: Tadokoro
mesh_terms: D000368:Aged; D002114:Calcinosis / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D012164:Retinal Diseases / Q000150:complications* / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications*