Palladium-catalysed intramolecular annulation of 2-haloanilines and ketones: enolate arylation vs. nucleophilic addition to the carbonyl group.
Two alternative annulation pathways involving either the enolate arylation or the addition to the ketone carbonyl group can operate in the Pd-catalysed intramolecular coupling of 2-haloanilines and ketones.
Solé
D
D
Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028-barcelona, Spain.
Vallverdú
L
L
Peidró
E
E
Bonjoch
J
J