title: [Diprivan-EDTA--choice in favor of patients safety].
abstract: Use of propofol in anesthesiology increases with every year. On the other hand, some data indicate a risk of postoperative complications caused by bacterial contamination of propofol solution in the course of its utilization. The probability of these complications reaches 6.3%. A modified formula of propofol (diprivan-EDTA) has been developed, which is characterized by antibacterial (bacteriostatic) effect towards 20 most prevalent microorganisms. Preliminary results of clinical evaluation of diprivan-EDTA safety indicate its positive effect on the incidence of severe postoperative complications and mortality of patients in intensive care wards.
authors.forename: A M
authors.initials: AM
authors.lastname: Ovechkin
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Gagarina
mesh_terms: D000771:Anesthesia, Intravenous / Q000379:methods; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D002614:Chelating Agents / Q000008:administration & dosage*; D004340:Drug Contamination / Q000517:prevention & control*; D004492:Edetic Acid / Q000008:administration & dosage*; D006801:Humans; D015742:Propofol / Q000008:administration & dosage*; D013594:Syringes
chemical_list: D018686:Anesthetics, Intravenous; D002614:Chelating Agents; D004492:Edetic Acid; D015742:Propofol