title: [Ecdysten in the treatment of giardiasis].
abstract: The drug ecdisten as tablets is the natural compound ecdisteron was extracted from Rhaponticum carthamoides (Willd.) Jljin. Ecdisten was tested in the treatment of 32 and 3 patients with persistent and acute giardiasis, respectively. A ten-day course of ecdisten, 5 mg 3 or 4 times a day, resulted in a clinical and parasitological recovery in 22 (68.7%) and 3 patients, respectively. After the reuse of a ecdisten course in 4 patients with persistent giardiasis wherein its initial dose was increased, recovery was achieved in 3 cases, the efficacy of the agent was 78.1%. Ecdisten should be used to treat giardiasis, in its chronic pattern or resistance to conventional giardicial agents.
authors.forename: S O
authors.initials: SO
authors.lastname: Osipova
authors.forename: Zh I
authors.initials: ZhI
authors.lastname: Islamova
authors.forename: V N
authors.initials: VN
authors.lastname: Syrov
authors.forename: N S
authors.initials: NS
authors.lastname: Badalova
authors.forename: Z A
authors.initials: ZA
authors.lastname: Khushbaktova
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004334:Drug Administration Schedule; D005260:Female; D005873:Giardiasis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D010936:Plant Extracts / Q000627:therapeutic use; D013256:Steroids / Q000627:therapeutic use*
chemical_list: D000981:Antiprotozoal Agents; D010936:Plant Extracts; D013256:Steroids; C088647:ecdystene