Antinociceptive and antidiarrhoeal activity of Zanthoxylum rhetsa.
The methanolic extract of the Zanthoxylum rhetsa Roxb. stem bark, given by oral route to mice at doses of 250 and 500 mg/kg, significantly reduced the abdominal contraction induced by acetic acid and the diarrhoeal episodes induced by castor oil in mice.
Rahman
M T
MT
Department of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh. mtrahmanbd@yahoo.com
Alimuzzaman
M
M
Ahmad
S
S
Chowdhury
A Asad
AA
D019342:Acetic Acid; D000700:Analgesics / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000930:Antidiarrheals / Q000627:therapeutic use*; D003967:Diarrhea / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D010146:Pain / Q000139:chemically induced / Q000188:drug therapy*; D010147:Pain Measurement / Q000187:drug effects; D008517:Phytotherapy; D024301:Plant Bark; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D027821:Rutaceae
D000700:Analgesics; D000930:Antidiarrheals; D010936:Plant Extracts; D019342:Acetic Acid