title: Extent of the cariostatic effect on root dentin provided by fluoride-containing restorative materials.
abstract: This study evaluated the extent of the cariostatic effect on root dentin provided by four fluoride-containing restorative systems: Ketac-Fil/ESPE [Ke], Fuji II LC Improved/GC Corp [Fj], Dyract AP/Dentsply [Dy] and SureFil/Dentsply [Su], and one without fluoride: Z250/3M [control]. Ninety-five bovine root dentin fragments (5.0 x 6.0 mm) were obtained, embedded in polyester resin and planed. Cavities (1.5 x 3.5 x 1.0 mm) were made and restored by the five restorative systems (n=19) in a randomized complete block design according to the manufacturers' instructions. After 24 hours, the dentin/restoration surface was polished. The restoration surface and an adjacent area of 3.0 x 3.0 mm were demarcated and submitted to a pH-cycling model. Dentin surface Knoop microhardness values were obtained (5.0-g, 5.0-s) for 10 distances: 50, 100, 150, 300, 600, 900, 1200, 1500, 1800 and 2100 microm from the margin of the restoration. The dentin microhardness means for each restorative material at each distance was considered by the ANOVA multi-factor split-plot method. The interaction between the restorative system and distance was statistically significant (p<0.05). The Tukey test and the regression analysis showed that the means of [Ke] and [Fj] were similar up to 300 microm, the [Ke] means being higher than the [control] at distances 50, 100, 150 and 300 microm. The [Fj] means were higher than the [control] at distances 50, 100 and 150 microm. The microhardness means of [Dy] and [Su] were not statistically different from the [control] and remained steady throughout the studied distances. This study concluded that the extent of the cariostatic effect on root dentin was 300 microm for [Ke] and 150 microm for [Fj]. [Dy] and [Su] did not show any cariostatic effect.
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, Piracicaba, State University of Campinas, Brazil.
authors.forename: A T
authors.initials: AT
authors.lastname: Hara
authors.forename: C P
authors.initials: CP
authors.lastname: Turssi
authors.forename: M C
authors.initials: MC
authors.lastname: Serra
authors.forename: M C S
authors.initials: MC
authors.lastname: Nogueira
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D017438:Bisphenol A-Glycidyl Methacrylate; D002327:Cariostatic Agents; D002417:Cattle; D020770:Compomers; D003188:Composite Resins; D003793:Dental Restoration, Permanent / Q000379:methods*; D003804:Dentin; D003808:Dentin Solubility; D017220:Dentin-Bonding Agents; D005459:Fluorides / Q000008:administration & dosage*; D005899:Glass Ionomer Cements; D006244:Hardness; D008298:Maleates; D008689:Methacrylates; D011109:Polymethacrylic Acids; D011897:Random Allocation; D012044:Regression Analysis; D012117:Resins, Synthetic; D017213:Root Caries / Q000517:prevention & control*; D017640:Silicates; D018709:Statistics, Nonparametric
chemical_list: D002327:Cariostatic Agents; D020770:Compomers; D003188:Composite Resins; D017220:Dentin-Bonding Agents; C088486:Dyract; C444701:Filtek Z250; C079765:Fuji II LC cement; D005899:Glass Ionomer Cements; D008298:Maleates; D008689:Methacrylates; D011109:Polymethacrylic Acids; C425843:Prime and Bond NT; D012117:Resins, Synthetic; D017640:Silicates; C403464:SureFil packable composite; C115612:single bond; D017438:Bisphenol A-Glycidyl Methacrylate; C040964:Ketac-Fil; D005459:Fluorides