title: Influence of specific treatment on the morbidity of Schistosomiasis mansoni in an endemic area of Minas Gerais, Brazil.
abstract: The authors describe the evolution of schistosomiasis mansoni in inhabitants of Capitão Andrade, Minas Gerais, Brazil, from 1973 to 1994. The prevalence of infection was 60.8% in 1973, 36.2% in 1984, and 27.3% in 1994. The evolution of the clinical forms of the disease in this group was as follows: unchanged in 76.7%, clinical progression in 8.4% and clinical regression in 14.9%. The reduction of the prevalence and severity of Schistosoma mansoni infection over the 21 years period, can be attributed to treatment of infected subjects performed in the area and to the installation of piped water in their dwellings.
authors.affiliation: Serviço de Doenças Infecciosas e Parasitárias, Hospital Universitário Clementino Fraga Filho, UFRJ, Rio de Janeiro, RJ, Brasil. conceicao@ioc.fiocruz.br
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Conceicao
authors.forename: J
authors.initials: J
authors.lastname: Borges-Pereira
mesh_terms: D000818:Animals; D001938:Brazil / Q000453:epidemiology; D019353:Endemic Diseases; D005500:Follow-Up Studies; D006801:Humans; D010073:Oxamniquine / Q000627:therapeutic use*; D015995:Prevalence; D012555:Schistosomiasis mansoni / Q000188:drug therapy* / Q000453:epidemiology; D012556:Schistosomicides / Q000627:therapeutic use*
chemical_list: D012556:Schistosomicides; D010073:Oxamniquine