Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation.
The allylic hydrogen is found to have a dramatic effect on the regioselectivity of the Wacker oxidation, leading to the postulation that an agostic hydrogen or enyl (sigma + pi) complex helps to stabilise the key intermediate.
Gaunt
M J
MJ
University of Chemical Laboratory, Lensfield Road, Cambridge, UK CB2 1EW.
Yu
J
J
Spencer
J B
JB