[Effects of immunization on proteinase-inhibitor balance in the lacrimal fluid and blood serum in alkaline burns of the cornea (an experimental study)].
Proteinase-inhibitor balance in the lacrimal fluid in eye burns was studied in rabbits with modified and intact immune status. Stimulation of the immune system was induced by complete Freund's adjuvant. Clinical picture of the disease was studied in parallel. Immunization accelerated the local adaptive and defense reaction of the proteolytic enzymes and their inhibitors, which was paralleled by a more benign course of burn disease of the eyes, in comparison with that in non-immunized animals.
Gulidova
O V
OV
Beznos
O V
OV
Shatinina
S Z
SZ
Chesnokova
N B
NB
D000468:Alkalies; D000818:Animals; D002057:Burns, Chemical / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D005126:Eye Burns / Q000139:chemically induced* / Q000276:immunology / Q000628:therapy*; D005500:Follow-Up Studies; D005620:Freund's Adjuvant; D007114:Immunization; D011480:Protease Inhibitors / Q000032:analysis* / Q000097:blood; D011817:Rabbits; D013666:Tears / Q000737:chemistry*; D013997:Time Factors
D000468:Alkalies; D011480:Protease Inhibitors; D005620:Freund's Adjuvant