[The research progress of using electroporation therapy in treatment of tumor].
In these years, the electrical technology is widely applied in the study of biomedical engineering. Using electroporation therapy (EPT) to treat tumor is associated with biomedical engineering, electrical new technology, computer technology and microelectronic technology, which is a new marginal subject. Many experts have studied the mechanism and clinical treatment of the cell membrane electroporation phenomenon under electrical fields. These researches have shown that the membrane electroporation can stimulate the transport and intake of various drugs, which improves the tumoricidal effect of these drugs. The researchers have also been exploring the phenomenon that irreversible electrical breakdown (IREB) of cell membrane under high electrical fields and steep pulses leads to the death of tumor.
Yao
Chenguo
C
College of Electrical Engineering, Chongqing University, Chongqing 400044.
Sun
Caixin
C
Xiong
Lan
L
Mi
Yan
Y
Hu
Lina
L
D002462:Cell Membrane / Q000648:ultrastructure; D053672:Electrochemotherapy; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D012106:Research / Q000639:trends