title: Estimation of choroid perfusion by colour Doppler imaging vs. other methods.
abstract: Ocular haemodynamics play a prominent role in several ocular diseases. Recently, new methods for the determination of ocular perfusion were developed. Colour Doppler imaging (CDI) of orbital vessels has come up in the past decade and was shown to be useful in ophthalmological diagnostics. Little is known about measurement of choroid perfusion by CDI in comparison with other methods. Therefore, 49 eyes were examined with CDI, laser Doppler flowmetry (LDF) and the method of Langham (LOBF). Correlations between the methods were identified by the Spearman correlation coefficient (r). LDF readings correlated with time-averaged mean velocity assessed by CDI in the long posterior ciliary artery (r = 0.47; p = 0.039; n = 20), but not in the short posterior ciliary artery. LOBF measurements correlated with pulsatility index (PI) of CDI in short (r = 0.50; p = 0.005; n = 30) and long posterior ciliary arteries (r = 0.41; p = 0.024; n = 30). Methods strengthened each other by partial correlation. The study demonstrates that CDI allows a more detailed insight into ocular perfusion.
authors.affiliation: Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Augenheilkunde, Hamburg, Germany. zeitz@uke.uni-hamburg.de
authors.forename: Oliver
authors.initials: O
authors.lastname: Zeitz
authors.forename: Eike T
authors.initials: ET
authors.lastname: Matthiessen
authors.forename: Gisbert
authors.initials: G
authors.lastname: Richard
authors.forename: Maren
authors.initials: M
authors.lastname: Klemm
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002831:Choroid Plexus / Q000098:blood supply* / Q000000981:diagnostic imaging*; D019842:Ciliary Arteries / Q000000981:diagnostic imaging; D005260:Female; D006439:Hemodynamics; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008875:Middle Aged; D018709:Statistics, Nonparametric; D018615:Ultrasonography, Doppler, Color