Ictal onset localization of epileptic seizures by magnetoencephalography.
OBJECTIVE
The aim of this study was to localize the ictal onset zone of focal epileptic seizures by magnetoencephalography (MEG) and to compare the results with interictal MEG localizations, ictal and interictal electroencephalography (EEG) results and magnetic resonance imaging (MRI) in epilepsy surgery candidates.


METHODS
Data of 13 patients with partial seizures during MEG recording were analysed. Measurements were performed with a Magnes II dual unit system.


RESULTS
In six of 13 cases, the ictal onset zone could be localized by MEG, with all interictal MEG findings being confirmed by ictal MEG results. In four cases, the ictal MEG localization results were corresponding to the ictal EEG localization results. In two cases, EEG yielded no comparable information.


CONCLUSIONS
Ictal onset localization is feasible with MEG. Both interical and ictal MEG contribute valuable information to the presurgical assessment of epilepsy patients.
Tilz
C
C
Department of Neurology, Epilepsy Center, Friedrich-Alexander University of Erlangen-Nuernberg, Germany. christian.tilz@neuro.med.uni-erlangen.de
Hummel
C
C
Kettenmann
B
B
Stefan
H
H
D000328:Adult; D001921:Brain / Q000503:physiopathology; D001931:Brain Mapping; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies