[Effects of heat and noise environments on lipid peroxidation erythrocyte membrane in pilots].
OBJECTIVE
To investigate the effects of heat and noise environments on lipid peroxidation of erythrocyte membrane in pilots.


METHODS
Twenty-four pilots and twenty-one ground personnel (control group) served as the subjects. The pilots performed flying in heat and noise environments. Glutathione peroxidase (GSHpx) and malondialdehyde [correction of malondiadehyde] (MDA) levels in erythrocyte membrane were determined before flying (6:00 a.m.), immediately after flying (12:00 a.m.) and 8 hours after flying (8:00 p.m.) respectively with a spectrophotometer.


RESULTS
Immediately after flying, GSHpx activity in pilot's erythrocyte membrane decreased significantly as compared with that in control group. Immediately after flying and 8 h after flying, MDA contents in pilots increased significantly as compared with that of control group.


CONCLUSIONS
Heat and noise environments might induce increase of lipid peroxidation reaction and decrease of antioxidant ability.
Hao
W W
WW
Naval General Hospital, Beijing, China.
Qin
S Z
SZ
Yu
Q F
QF
Li
M G
MG
Ma
G X
GX
Zhao
H
H
D000328:Adult; D000337:Aerospace Medicine; D001359:Aviation; D004910:Erythrocyte Membrane / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D005979:Glutathione Peroxidase / Q000097:blood / Q000378:metabolism; D006358:Hot Temperature; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008315:Malondialdehyde / Q000097:blood / Q000378:metabolism; D009623:Noise, Occupational
D008315:Malondialdehyde; D005979:Glutathione Peroxidase