title: Estimation of the incidence of pleural mesothelioma according to death certificates in France.
abstract: BACKGROUND
  The number of cases of pleural mesothelioma in France has varied substantially according to methods of assessment.
  
  
  METHODS
  We collected information from certifying physicians about 316 subjects who died between 1 July 1992 and 30 June 1993 in three regions of France with a cause of death coded as ICD-9 category 163. The ICD codes selected as the cause of death for 178 deaths between 1 January 1987 and 31 December 1992 histologically confirmed and diagnosed as pleural mesothelioma by an expert committee were examined. Finally, we used this information to estimate the number of deaths from pleural mesothelioma in France in 1992.
  
  
  RESULTS
  In Part I, 45% (men: 54%; women: 28%) of the cases coded as ICD-9 section 163 were definitely or probably mesothelioma; 18% (men: 16%; women: 21%) possibly mesothelioma; and 37% (men: 30%; women: 51%) other tumors, primarily adenocarcinoma metastases. In Part II, 74% of the confirmed pleural mesotheliomas were coded in category 163 (men: 75%; women: 70%). Extrapolation nationwide indicated that 902 deaths were coded as ICD-9 163 in 1992: 521 cases involved definite or probable mesothelioma and 724 definite, probable, and possible cases.
  
  
  CONCLUSIONS
  The analysis of this sample suggests that estimating the number of mesothelioma cases from the cause-of-death statistics may overestimate their incidence, but that death certificates appeared to report the diagnosis of histologically confirmed mesothelioma accurately.
authors.affiliation: INSERM E99-09, Créteil, France. y.iwatsubo@invs.sante.fr
authors.forename: Y
authors.initials: Y
authors.lastname: Iwatsubo
authors.forename: M
authors.initials: M
authors.lastname: Matrat
authors.forename: E
authors.initials: E
authors.lastname: Michel
authors.forename: C
authors.initials: C
authors.lastname: Boutin
authors.forename: F
authors.initials: F
authors.lastname: Galateau-Salle
authors.forename: E
authors.initials: E
authors.lastname: Jougla
authors.forename: J
authors.initials: J
authors.lastname: Bignon
authors.forename: J C
authors.initials: JC
authors.lastname: Pairon
authors.forename: P
authors.initials: P
authors.lastname: Brochard
mesh_terms: D017677:Age Distribution; D000368:Aged; D002423:Cause of Death; D003644:Death Certificates; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008654:Mesothelioma / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality*; D008875:Middle Aged; D010865:Pilot Projects; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality*; D011237:Predictive Value of Tests; D011336:Probability; D012042:Registries; D018570:Risk Assessment; D017678:Sex Distribution