title: Surgical management of early stage cervical cancer: ten years experience from one Greek health region.
abstract: OBJECTIVE
  Cervical cancer is the second most common malignancy in women, in both incidence and mortality. In the present study, we report our results of treating 93 consecutive patients with early invasive cervical cancers (Stages I-IIA).
  
  
  METHODS
  The patients of this study comprised all women recognized with stage I-IIA cervical cancer during 1991-2000. Patients with stage IA1 cervical cancer without lymphvascular space involvement underwent either conservative management by means of large loop conization or simple hysterectomy. The remaining patients underwent radical hysterectomy and lymphadenectomy or radiation therapy. Mean (+/- SD) duration of follow-up was 6 (+/- 1.7) years.
  
  
  RESULTS
  The mean (+/- SD) age of patients with stage I-IIA cervical cancer was 41.3 (+/- 9.1) year. Thirty-five patients with stage [A1 disease were managed conservatively with loop excision and 19 patients subsequently became pregnant. Fifty-two patients with stage IA2, IB and IIA cervical carcinoma underwent radical hysterectomy and lymphadenectomy.
  
  
  CONCLUSIONS
  Young women with stage IA1 cervical carcinoma wishing future fertility who undergo loop excision have a 100% cure rate. Women with stage IA2, IB, and IIA cervical cancer should undergo radical hysterectomy and lymphadenectomy or radiation therapy.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital, Ioannina, Greece.
authors.forename: E
authors.initials: E
authors.lastname: Paraskevaidis
authors.forename: S N
authors.initials: SN
authors.lastname: Kalantaridou
authors.forename: A
authors.initials: A
authors.lastname: Kaponis
authors.forename: S
authors.initials: S
authors.lastname: Chouliara
authors.forename: N J
authors.initials: NJ
authors.lastname: Agnantis
authors.forename: V
authors.initials: V
authors.lastname: Dousias
authors.forename: K
authors.initials: K
authors.lastname: Zikopoulos
authors.forename: M
authors.initials: M
authors.lastname: Paschopoulos
authors.forename: P
authors.initials: P
authors.lastname: Stamatopoulos
authors.forename: D E
authors.initials: DE
authors.lastname: Lolis
mesh_terms: D000328:Adult; D019092:Conization; D005260:Female; D006115:Greece / Q000453:epidemiology; D006801:Humans; D007044:Hysterectomy; D015994:Incidence; D008197:Lymph Node Excision; D008875:Middle Aged; D009367:Neoplasm Staging; D011247:Pregnancy; D011256:Pregnancy Outcome; D018714:Radiotherapy, Adjuvant; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*