30 mm regeneration of rat sciatic nerve along collagen filaments.
This paper describes 30 mm regeneration of peripheral nerve axons along collagen filaments; 31-mm-long collagen filaments or collagen tube were grafted to bridge a 30-mm defect of rat sciatic nerve. The mean number and the diameter of regenerated myelinated axons were 330+/-227 and 2.7+/-0.9 microm at the distal end of the collagen-filaments 12 weeks postoperatively; while at the distal end of the tube no axon was found.
Yoshii
Satoru
S
Institute of Biomedical Engineering, Kansai Denryoku Hospital, Imaichi 2-7-14, Asahi-ku, 535-0011 Osaka, Japan. K-20433@kepco.co.jp
Oka
Masanori
M
Shima
Mitsuhiro
M
Taniguchi
Ataru
A
Akagi
Masao
M
D000818:Animals; D003094:Collagen / Q000627:therapeutic use; D008297:Male; D009416:Nerve Regeneration; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000254:growth & development / Q000293:injuries / Q000502:physiology*
D003094:Collagen