Lead and the developing nervous system.
Subtle signs of neural impairment are appearing in children exposed to "low levels" of lead. How does this metal exert its effect on the developing nervous system? The salient features of five mechanisms likely involved are discussed in this review.
De Gennaro
Louis D
LD
Biology Department, Le Moyne College, Syracuse, New York 13214, USA.
D000818:Animals; D001808:Blood Vessels / Q000187:drug effects; D002648:Child; D004785:Environmental Pollutants / Q000506:poisoning; D015870:Gene Expression / Q000187:drug effects; D006801:Humans; D020264:Lead Poisoning, Nervous System, Childhood / Q000209:etiology* / Q000235:genetics / Q000378:metabolism; D009420:Nervous System / Q000187:drug effects; D009928:Organ Specificity; D018384:Oxidative Stress / Q000187:drug effects
D004785:Environmental Pollutants