[Relationship between hepatitis G virus infection and hepatic failure].
OBJECTIVE
To study the pathogenic effect of hepatitis G virus (HGV) infection on hepatic failure.


METHODS
Using the RT-PCR and EIA techniques to detect HGV RNA and anti-HGV in sera of hepatic failure patients and compare them with their liver function and mortality rates.


RESULTS
There was no significant difference about the positive rates of HGV among acute hepatic failure, subacute hepatic failure and chronic hepatic failure groups (X(2)=2.54, P>0.05). The level of ALT in HGV-positive group was slightly lower than that in HGV-negative group. The concentration of bilirubin and globulin was higher in HGV-positive group than HGV-negative group, and the concentration of albumin in HGV-positive group was significantly lower than that in HGV-negative group (t=2.59, P<0.05). The mortality rate in HGV-positive group was significantly lower than that in HGV-negative group (X(2)=4.68, 0.01<P<0.05).


CONCLUSIONS
The virulence of HGV is mild, and the HGV infection does not aggravate hepatic failure.
Xiong
Liang Shi
LS
Affiliate Hospital of North Sichuan Medical College, Nanchong 637000, China.
Liang
Runqin
R
Cui
Sufen
S
Zhou
Jing Guo
JG
Xing
Yan
Y
D000328:Adult; D005260:Female; D018178:Flaviviridae Infections / Q000150:complications*; D029407:GB virus C / Q000472:pathogenicity*; D006525:Hepatitis, Viral, Human / Q000150:complications*; D006801:Humans; D017093:Liver Failure / Q000209:etiology*; D008297:Male; D008875:Middle Aged