Late response to donor lymphocyte infusions in patients with chronic myeloid leukemia relapsing after allogeneic stem cell transplantation.
Donor lymphocyte infusions were given to 13 consecutive chronic myeloid leukemia patients in relapse after allogeneic stem cell transplantation. Of the 13 patients, 11 achieved a molecular remission and 2 a cytogenetic remission. The median time (range) in months to achieve a hematologic, cytogenetic and molecular remission was 2 (1-2), 5 (1-42) and 5 the median response duration is 16 months (range 1-36), and no patient shows evidence of relapse.
Gómez
Marta
M
Urbano-Ispizua
Alvaro
A
Cervantes
Francisco
F
Fernández-Avilés
Francesc
F
Rovira
Montserrat
M
Carreras
Enric
E
D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy*; D017710:Lymphocyte Transfusion; D012008:Recurrence; D033581:Stem Cell Transplantation; D013997:Time Factors; D014184:Transplantation, Homologous; D016896:Treatment Outcome