The origins of a concept: the protease-antiprotease imbalance hypothesis.
Turino
Gerard M
GM
Department of Medicine, Columbia University College of Physicians and Surgeons, and James P. Mara Center for Lung Disease, St. Luke's-Roosevelt Hospital, New York, NY 10019, USA. gmt1@columbia.edu
D000818:Animals; D002356:Cartilage / Q000503:physiopathology; D010450:Endopeptidases / Q000502:physiology*; D006801:Humans; D008168:Lung / Q000503:physiopathology; D011480:Protease Inhibitors / Q000378:metabolism*; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D011656:Pulmonary Emphysema / Q000503:physiopathology*; D011817:Rabbits
D011480:Protease Inhibitors; D010450:Endopeptidases