Microbial transformation of a beta- and gamma-eudesmols mixture.
Beta- and gamma-eudesmols mixture was microbiologically transformed by Gibberella suabinetti ATCC 20193. Seven different eudesmanoidal metabolites (3-9) were isolated and their structures were elucidated by the different spectroscopic techniques. These metabolites are: eudesma-4-en-11-ol-3-one (carissone), eudesma-3-en-2beta, 11-diol, eudesma-4-en-3beta,11-diol, eudesma-4(15)-en-8,11-diol, eudesma-4(15)-en-2a,11-diol (pterocarpol), 1(3)cyclo-eudesma-4(15)-en-11,12-diol and eudesma-4-en-11,15-diol.
Maatooq
Galal T
GT
University of Mansoura, Faculty of Pharmacy, Department of Pharmacognosy, Egypt. galaltm@mans.edu.eg
D001711:Biotransformation; D005874:Gibberella / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D009904:Optical Rotation; D013729:Terpenes / Q000493:pharmacokinetics*
D013729:Terpenes