A regioselective cycloaddition route to isoxazoleboronic esters.
Alkynylboronates participate in 1,3-dipolar cycloaddition reactions with nitrile oxides to provide isoxazoleboronic esters with excellent levels of regiocontrol; additionally, these potentially valuable synthetic intermediates have been shown to participate efficiently in Suzuki coupling reactions.
Davies
M W
MW
Department of Chemistry, University of Sheffield, Sheffield, UK S3 7HF.
Wybrow
R A
RA
Johnson
C N
CN
Harrity
J P
JP