title: Mycosis fungoides causing severe lower eyelid ulceration.
abstract: Mycosis fungoides is a form of cutaneous malignant T-cell lymphoma initially confined to the skin. A range of ophthalmic manifestations has been described; these usually appear in advanced disease. Lid involvement is most common and ranges from ectropion, usually cicatricial, to diffuse thickening and placoid tumours. A case of a 72-year-old man presenting with progressive, full thickness, lower eyelid ulceration is presented. The patient had a long history of placoid skin lesions, previously diagnosed as discoid lupus. Repeat biopsies of these lesions including the eyelid eventually revealed mycosis fungoides. The ulceration progressed to destroy most of the lower lid before the correct diagnosis was made. This type of eyelid involvement has not previously been reported in mycosis fungoides. This case also highlights the diagnostic difficulties encountered in the early phases of mycosis fungoides. If suspected, multiple biopsies are essential to establish the diagnosis.
authors.affiliation: Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. justingame@mac.com
authors.forename: Justin A
authors.initials: JA
authors.lastname: Game
authors.forename: Rodger
authors.initials: R
authors.lastname: Davies
mesh_terms: D000368:Aged; D005141:Eyelid Diseases / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D009182:Mycosis Fungoides / Q000150:complications* / Q000175:diagnosis; D012878:Skin Neoplasms / Q000150:complications* / Q000175:diagnosis; D014456:Ulcer / Q000209:etiology* / Q000473:pathology