title: [Intraoperative application of acute normovolemic hemodilution].
abstract: To investigate the effects of acute normovolemic hemo-dilution(ANHD) on hemodynamics and hemobiochemistry during surgery. In 30 patients(ASA Grade I-III) undergoing selective surgery, ANHD was accomplished by exchanging whole blood(8.0 +/- 2.7) ml.kg-1 with an equal volume of gelofusine after induction of anesthesia. The results showed: after ANHD, Hb, Hct and Plc levels respectively decreased by 13.8%(P < 0.05), 17.1%(P < 0.05) and 7.1%(P > 0.05), and yet kept in normal range; MAP, HR, SpO2, ECG maintained the normal level; and no significant changes were observed in the concentration of Na+, K+ and Cl-. ANHD is a safe and effective technique of autotransfusion, and can decrease or avoid the risk of disease transmission.
authors.affiliation: Department of Anesthesiology, Xiangya Hospital, Hunan Medical University, Changsha 410008.
authors.forename: S P
authors.initials: SP
authors.lastname: Zhao
authors.forename: H W
authors.initials: HW
authors.lastname: Cai
authors.forename: Z S
authors.initials: ZS
authors.lastname: Liu
authors.forename: H W
authors.initials: HW
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000503:physiopathology / Q000601:surgery; D017558:Elective Surgical Procedures; D005260:Female; D005780:Gelatin / Q000627:therapeutic use*; D006438:Hemodilution; D006439:Hemodynamics; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010952:Plasma Substitutes / Q000627:therapeutic use; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood; D013386:Succinates / Q000627:therapeutic use*
chemical_list: D010952:Plasma Substitutes; D013386:Succinates; C060085:succinylated gelatin; D005780:Gelatin; D012964:Sodium; D011188:Potassium