title: Persistent asthma: disease control, resource utilisation and direct costs.
abstract: Despite evidence that adverse outcomes are less frequent when asthma management is optimised, the link between the level of control, disease severity and medical resource utilisation (MRU) is poorly documented. This relationship was investigated in a group of patients suffering from persistent asthma (Global Initiative for Asthma (GINA) > or = 2) in France. In 1998 a computerised family practice database was used to identify asthma patients aged 17-50 yrs. Information from the database was complemented by a patient survey to retrospectively assess the level of asthma control and hospital contacts. Costs of MRU over a 12-month study period were related to demographics, medical history, asthma control, and doses of inhaled corticosteroids prescribed during the prestudy period. A review of the computerised medical database identified 1,038 adult patients with persistent asthma, who completed the survey questionnaire. Over a 12-month period, the mean cost of MRU was 549.8 euros for well-controlled patients, 746.3 euros per patient with moderate control, and 1,451.3 euros per patient with poor control. Costs also increased significantly with age, access to free asthma care, comorbid conditions, asthma symptoms in the past year and whether inhaled corticosteroids had been prescribed before the study period. In patients with persistent asthma, large differences were observed in the use of medical resources according to control and severity. Therefore, if patients appropriately use prescribed control therapy, their use of medical resources may be reduced.
authors.affiliation: Pharmacoepidemiology Unit, and Poison Centre, Claude-Bernard University, Lyon, France. eric.vanganse@chu-lyon.fr
authors.forename: E
authors.initials: E
authors.lastname: Van Ganse
authors.forename: L
authors.initials: L
authors.lastname: Laforest
authors.forename: G
authors.initials: G
authors.lastname: Pietri
authors.forename: J P
authors.initials: JP
authors.lastname: Boissel
authors.forename: F
authors.initials: F
authors.lastname: Gormand
authors.forename: R
authors.initials: R
authors.lastname: Ben-Joseph
authors.forename: P
authors.initials: P
authors.lastname: Ernst
mesh_terms: D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000191:economics* / Q000517:prevention & control*; D017281:Cost of Illness; D005260:Female; D005602:France; D015438:Health Behavior; D017048:Health Care Costs / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000191:economics / Q000706:statistics & numerical data; D040841:Resource Allocation / Q000191:economics* / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012720:Severity of Illness Index