Dental management of a pediatric patient with mastocytosis: a case report.
Mastocytosis is a heterogeneous group of clinical disorders characterized by an excessive number of normal mast cells in a variety of tissues (skin, bone marrow, liver, spleen and lymph nodes). It is most often seen in the skin in pediatric-onset mastocytosis presenting as urticaria pigmentosa. Children with this disorder are on a strict avoidance protocol of triggering factors to decrease the likelihood of life-threatening anaphylactic reactions. Close monitoring and the avoidance of known histamine-releasing drugs is necessary in the pediatric dental office, as is a readiness to use resuscitative measures. A case of a 4-year, 6-month-old pediatric dental patient with mastocytosis is presented. Dental treatment was provided in an ambulatory setting utilizing nitrous oxide, oxygen analgesia and H1 and H2 antihistamines to prevent mast cell degranulation and to provide sedation.
Nelson
Linda P
LP
Department of Pediatric Dentistry, Children's Hospital, Boston, Mass, USA. linda_nelson@hsdm.harvard.edu
Savelli-Castillo
Ilse
I
D000707:Anaphylaxis / Q000517:prevention & control; D000766:Anesthesia, Dental / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D015550:Cell Degranulation; D002675:Child, Preschool; D016292:Procedural Sedation / Q000379:methods*; D017742:Dental Care for Chronically Ill; D003731:Dental Caries / Q000628:therapy; D003793:Dental Restoration, Permanent; D006633:Histamine Antagonists / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008415:Mastocytosis; D009609:Nitrous Oxide / Q000008:administration & dosage; D011229:Preanesthetic Medication
D018685:Anesthetics, Inhalation; D006633:Histamine Antagonists; D009609:Nitrous Oxide