title: Molecular Genetic Evidence of the Ability of Alternative Oxidase to Support Respiratory Carbon Metabolism.
abstract: With the cytochrome pathway inhibited, AOX was able to support considerable growth of cultured tobacco (Nicotiana tabacum cv Petit Havana SR1) cells but the efficiency of carbon utilization decreased dramatically. Antisense cells with decreased AOX protein did not grow, whereas sense cells with elevated AOX protein had higher growth and respiration rates than the wild type. In antisense cells a large accumulation of pyruvate resulted in aerobic ethanolic fermentation.
authors.affiliation: Department of Botany and Division of Life Sciences, University of Toronto at Scarborough, 1265 Military Trail, Scarborough, Ontario, Canada M1C 1A4 (G.C.V., A.E.V.).
authors.forename: G. C.
authors.initials: GC
authors.lastname: Vanlerberghe
authors.forename: A. E.
authors.initials: AE
authors.lastname: Vanlerberghe
authors.forename: L.
authors.initials: L
authors.lastname: McIntosh