title: Neurovascular rescue for embolic stroke following atrial septal defect closure.
abstract: Strokes following cardiac surgery occur in about 5% of patients. Intra-arterial thrombolysis is a good option in such a setting where intravenous thrombolysis is contraindicated, and when in-hospital strokes are detected well within the window for treatment and the chances of complete reperfusion are maximum. On postoperative day 4 after atrial septal defect correction, a 34-year-old woman with paroxysmal atrial fibrillation developed left middle cerebral artery stroke causing severe neurological deficits. Intra-arterial thrombolysis with urokinase led to remarkable recovery.
authors.affiliation: Department of Neurology and Cardiology, Amrita Institute of Medical Sciences and Research Centre, Kochi.
authors.forename: M A
authors.initials: MA
authors.lastname: Joy
authors.forename: Anand
authors.initials: A
authors.lastname: Kumar
authors.forename: K V
authors.initials: KV
authors.lastname: Hariprasad
authors.forename: Prakash
authors.initials: P
authors.lastname: Kamath
authors.forename: K K
authors.initials: KK
authors.lastname: Haridas
mesh_terms: D000328:Adult; D002533:Cerebral Angiography; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006344:Heart Septal Defects, Atrial / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology; D020521:Stroke / Q000188:drug therapy* / Q000209:etiology; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D014568:Urokinase-Type Plasminogen Activator