title: Enantioselective deprotonation reactions using polymer-supported chiral magnesium amide bases.
abstract: Novel and readily accessible polymer-supported chiral magnesium amide reagents have been prepared and shown to be effective in the asymmetric deprotonation of a series of prochiral cyclohexanones, affording good to excellent levels of both conversion and enantiomeric ratio (up to 93:7); the Merrifield-based chiral amine species has been shown to be readily recyclable.
authors.affiliation: Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow, Scotland, UK G1 1XL.
authors.forename: K W
authors.initials: KW
authors.lastname: Henderson
authors.forename: W J
authors.initials: WJ
authors.lastname: Kerr
authors.forename: J H
authors.initials: JH
authors.lastname: Moir