A case of extramedullary plasmacytoma of the larynx.
An 84-year-old male with a complaint of hoarseness was examined. A mass lesion was recognized in the false vocal fold. The tumor was excised and found to consist of atypical plasmacytes. Immunopathological examination revealed that leukocyte common antigen (CD45), UCHLI (CD45RO), CD3 and L26 (CD20) were negative and that CD79 and Vs38C were positive. Neither uric Bence-Jones protein nor serum M-protein were observed. No other bony abnormalities were recognized on X-ray examinations including both bone and Ga scintigraphy. No atypical plasmacyte infiltration was observed in bone marrow. Our final diagnosis was extramedullary plasmacytoma of the larynx. Radiotherapy was performed following surgery. The tumor did not progress to multiple myeloma and no recurrence has been observed after 2 years.
Kamijo
Takahiro
T
Department of Otolaryngology, Head and Neck Surgery, Kitasato Institute Medical Center Hospital, Saitama, Kanagawa, Japan. kamijo-t@kitasato.or.jp
Inagi
Katsuhide
K
Nakajima
Masami
M
Motoori
Tadashi
T
Tadokoro
Katsumi
K
Nishiyama
Shougo
S
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D010954:Plasmacytoma / Q000175:diagnosis* / Q000628:therapy*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000628:therapy*