title: Zanamivir is an effective treatment for influenza in children undergoing therapy for acute lymphoblastic leukemia.
abstract: We diagnosed influenza infection in 2 children receiving maintenance treatment for acute lymphoblastic leukemia. Both patients received zanamivir within 1 d of the onset of fever and their symptoms of influenza were rapidly alleviated. We conclude that inhaled zanamivir seems to be an effective treatment for influenza infection in immunocompromised patients.
authors.affiliation: Department of Pediatrics, Nippon Medical School, Tokyo, Japan. maeda@nms.ac.jp
authors.forename: Miho
authors.initials: M
authors.lastname: Maeda
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Fukunaga
authors.forename: Takeshi
authors.initials: T
authors.lastname: Asano
authors.forename: Makoto
authors.initials: M
authors.lastname: Migita
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ueda
authors.forename: Jun
authors.initials: J
authors.lastname: Hayakawa
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006146:Guanidines; D006801:Humans; D007251:Influenza, Human / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011714:Pyrans; D018570:Risk Assessment; D012794:Sialic Acids / Q000627:therapeutic use*; D016896:Treatment Outcome; D053243:Zanamivir
chemical_list: D000998:Antiviral Agents; D006146:Guanidines; D011714:Pyrans; D012794:Sialic Acids; D053243:Zanamivir