title: Lining the mouth floor with prelaminated fascio-mucosal free flaps: clinical experience.
abstract: Soft-tissue defects of the mouth floor need thin, foldable, and pliable tissues able to preserve local anatomy as well as chewing, phonation, and deglutition. The oral mucosa is made of a stratified, nonkeratinized, epithelium-secreting mucus, which lubricates the oral cavity and facilitates tongue movements. No flap exists that can reproduce the physiology of the oral mucosa better than the oral mucosa itself. Prefabrication of mucosal flaps may represent the best solution. Therefore, 10 consecutive cases of mouth floor cancer were treated with prelamination of the fascia antibrachialis with mucosal grafts obtained from the healthy cheek, and with subsequent transplantation 3 weeks later. A significant increase in mucosal graft surface was seen in all cases, with a mean size twice the original. All flaps healed uneventfully. Follow-up time ranged between 2-60 months (average, 26.6 months). Morphological and functional results were excellent. Tongue motility, speech intelligibility, and swallowing were reestablished in all treated cases. Mucosal prelamination of the forearm fascia is feasible and allows physiological reconstruction of oral cavity defects up to 6 x 4 cm.
authors.affiliation: Section of Dentistry, Department of Neurosciences, Head and Neck and Rehabilitation, Faculty of Medicine, University of Modena and Reggio Emilia, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Chiarini
authors.forename: G
authors.initials: G
authors.lastname: De Santis
authors.forename: A
authors.initials: A
authors.lastname: Bedogni
authors.forename: P F
authors.initials: PF
authors.lastname: Nocini
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D000071938:Fasciotomy; D005260:Female; D005500:Follow-Up Studies; D005542:Forearm; D006801:Humans; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor; D009061:Mouth Mucosa / Q000601:surgery; D009062:Mouth Neoplasms / Q000601:surgery*; D013524:Surgical Flaps; D013997:Time Factors