title: Effect of the interval between shearing and dipping on the spread of Corynebacterium pseudotuberculosis infection in sheep.
abstract: OBJECTIVE
  To determine whether the spread of Corynebacterium pseudotuberculosis infection to sheep in dips could be controlled by increasing the time between shearing and dipping.
  
  
  METHODS
  A controlled treatment trial where only the time between shearing and dipping was varied. ANIMALS AND PROCEDURE: One hundred and ninety-five sheep were found to be negative for C. pseudotuberculosis exposure by assay of CLA toxin antibody, were divided into four treatment groups. Each was shorn at either 0, 2, 4 or 8 weeks before dipping in a solution containing C. pseudotuberculosis. Blood samples were taken 6 weeks after dipping and sheep were slaughtered 12 weeks after dipping. A fifth smaller group of 14 sheep shorn 26 weeks before dipping, was also exposed to C. pseudotuberculosis and was slaughtered with the other sheep.
  
  
  RESULTS
  The occurrence of caseous lymphadenitis abscesses did not differ between groups or with sheep shorn 26 weeks before dipping. The proportion of sheep that seroconverted to the C. pseudotuberculosis toxin and cell wall ELISA was larger in sheep dipped immediately after shearing than in sheep in the other groups.
  
  
  CONCLUSIONS
  Delaying dipping until 8 weeks after shearing did not decrease the C. pseudotuberculosis infection rate due to dipping. Sheep dipped immediately after shearing developed higher concentrations of antibody to C. pseudotuberculosis than sheep when dipping occurred between 2 and 8 weeks and later after shearing.
authors.affiliation: Avon Districts Agriculture Centre, Agriculture Western Australia, Northam.
authors.forename: M W
authors.initials: MW
authors.lastname: Paton
authors.forename: N B
authors.initials: NB
authors.lastname: Buller
authors.forename: I R
authors.initials: IR
authors.lastname: Rose
authors.forename: T M
authors.initials: TM
authors.lastname: Ellis
mesh_terms: D000822:Animal Husbandry / Q000379:methods*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001427:Bacterial Toxins; D003354:Corynebacterium Infections / Q000097:blood / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D016925:Corynebacterium pseudotuberculosis / Q000276:immunology; D018562:Disease Transmission, Infectious / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D008199:Lymphadenitis / Q000097:blood / Q000382:microbiology / Q000662:veterinary; D011897:Random Allocation; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood / Q000382:microbiology / Q000635:transmission*; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D001427:Bacterial Toxins