title: Sequence comparison of the dopamine receptor D4 exon III repetitive region in several species of the order Carnivora.
abstract: It was previously demonstrated that the dog dopamine receptor D4 (DRD4) gene is polymorphic in terms of the repeat number and/or order of 39- and 12-bp sequences located in the third exon. To examine whether or not the repetitive region is present in other species of the order Carnivora, the homologous region of DRD4 genes were sequenced in the gray wolf, raccoon dog, Asiatic black bear, common raccoon and domestic cat. In the family Canidae, the wolf had an identical sequence to that of the dog 447b allele, and a repetitive sequence similar to the dog DRD4 was also recognized in the raccoon dog. On the other hand, no obvious repeated structure was observed in the sequences of the bear, raccoon and cat.
authors.affiliation: Faculty of Agriculture, Gifu University, Japan.
authors.forename: Miho
authors.initials: M
authors.lastname: Inoue-Murayama
authors.forename: Naoto
authors.initials: N
authors.lastname: Matsuura
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Murayama
authors.forename: Toshio
authors.initials: T
authors.lastname: Tsubota
authors.forename: Toshiroh
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kitagawa
authors.forename: Shin'ichi
authors.initials: S
authors.lastname: Ito
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002335:Carnivora / Q000235:genetics*; D002415:Cats; D004285:Dogs; D005091:Exons; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011110:Polymorphism, Genetic; D011821:Raccoons; D011954:Receptors, Dopamine / Q000737:chemistry* / Q000145:classification* / Q000235:genetics; D020449:Repetitive Sequences, Amino Acid; D016415:Sequence Alignment / Q000662:veterinary; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D001503:Ursidae; D019596:Wolves
chemical_list: D011954:Receptors, Dopamine