title: [Stable life prediction for a complex injection of Chinese materia medica by initial average rate stability test].
abstract: OBJECTIVE
  To predict the stable life for a complex injection of Chinese materia medica.
  
  
  METHODS
  The prediction was carried out by initial average rate stability tests, and the contents of puerarin and danshensu (major active components of the injection) were assayed by HPLC.
  
  
  RESULTS
  The degradation of puerarin followed the first order action, while danshensu was hard to determine; the t0.9,25 degrees C was 3.49 years and 1.69 years respectively.
  
  
  CONCLUSIONS
  The stable life of the injection has been determined as 1.5 years.
authors.affiliation: Fudan University, Shanghai 200433, China.
authors.forename: B
authors.initials: B
authors.lastname: Jiang
authors.forename: S X
authors.initials: SX
authors.lastname: Hou
authors.forename: L L
authors.initials: LL
authors.lastname: Sun
authors.forename: S K
authors.initials: SK
authors.lastname: Liu
authors.forename: Z W
authors.initials: ZW
authors.lastname: Li
mesh_terms: D004338:Drug Combinations; D004355:Drug Stability; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007267:Injections; D007529:Isoflavones / Q000032:analysis; D007773:Lactates / Q000032:analysis; D010946:Plants, Medicinal / Q000737:chemistry*; D029908:Pueraria / Q000737:chemistry; D027561:Salvia miltiorrhiza / Q000737:chemistry
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D007529:Isoflavones; D007773:Lactates; C035055:3,4-dihydroxyphenyllactic acid; C033607:puerarin