Regioselective cyclization of alpha,omega-alkynoic acids catalysed by TpRu complexes: synthesis of endocyclic enol lactones [Tp = hydrotris(pyrazolyl)borate].
The sigma-enynyl complex [TpRu(C(Ph)=C(Ph)C identical to CPh)(P-MeiPr2)] efficiently catalyses the regioselective cyclization of alpha,omega-alkynoic acids to yield endocyclic enol lactones having ring size up to 12 atoms.
Jiménez-Tenorio
M
M
Departamento de Ciencia de Materiales e Ingeniería Metalúrgica y Química Inorgánica, Facultad de Ciencias, Universidad de Cádiz, Apartado 40, 11510 Puerto Real, Cádiz, Spain.
Puerta
M C
MC
Valerga
P
P
Moreno-Dorado
F J
FJ
Guerra
F M
FM
Massanet
G M
GM
D000480:Alkynes; D002264:Carboxylic Acids / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry
D000480:Alkynes; D002264:Carboxylic Acids; D007783:Lactones; D009942:Organometallic Compounds; D012428:Ruthenium