title: A historical appraisal of the use of cryopreserved and glycerol-preserved allograft skin in the treatment of partial thickness burns.
abstract: Two studies into the use of allograft skin in the treatment of partial thickness burn injuries in this burn centre have provided the opportunity to discuss changes and similarities over a 20 year period. The first study described results obtained with cryopreserved allografts in partial thickness burns in the period 1979-1981. The second study concerned patients with partial thickness injuries treated with glycerol-preserved allografts in the period 1998-2000. A reduction was noted concerning the need for secondary autografting in the group treated with glycerolized allografts. The probability that this difference has occurred by chance is small (P=0.089). Various other factors that might account for the differences in outcome, include general improvements in health and social welfare, differences in treatment protocols, and differences in allograft properties. A prospective comparative trial is indicated to study direct differences between the two types of allograft.
authors.affiliation: Burn Centre, Rode Kruis Ziekenhuis, Vondellaan 13, 1942 LE Beverwijk, The Netherlands. bwcavm@rkz.nl
authors.forename: A F P M
authors.initials: AF
authors.lastname: Vloemans
authors.forename: E
authors.initials: E
authors.lastname: Middelkoop
authors.forename: R W
authors.initials: RW
authors.lastname: Kreis
mesh_terms: D002056:Burns / Q000601:surgery*; D002675:Child, Preschool; D015925:Cryopreservation / Q000639:trends; D005260:Female; D005990:Glycerol; D006801:Humans; D009426:Netherlands; D019188:Organ Preservation Solutions; D012086:Reoperation; D012189:Retrospective Studies; D012867:Skin; D016038:Skin Transplantation / Q000379:methods* / Q000639:trends; D014021:Tissue Preservation / Q000379:methods* / Q000639:trends
chemical_list: D019188:Organ Preservation Solutions; D005990:Glycerol