title: Functional evolution of Hox proteins in arthropods.
abstract: It is presumed that the evolution of morphological diversity in animals and plants is driven by changes in the developmental processes that govern morphology, hence basically by changes in the function and/or expression of a defined set of genes that control these processes. A large body of evidence has suggested that changes in developmental gene regulation are the predominant mechanisms that sustain morphological evolution, being much more important than the evolution of the primary sequences and functions of proteins. Recent reports challenge this idea by highlighting functional evolution of Hox proteins during the evolutionary history of arthropods.
authors.affiliation: Evolution et Developpement des protostomiens, Centre de Genetique Moleculaire, UPR 2167 CNRS. 1, av. de la terrasse; 91198 Gif-sur-Yvette Cedex, France. vervoot@cgm.cnrs-gif.fr
authors.forename: Michel
authors.initials: M
authors.lastname: Vervoort
mesh_terms: D000818:Animals; D001181:Arthropods / Q000235:genetics* / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000502:physiology; D029721:Drosophila Proteins / Q000235:genetics* / Q000502:physiology; D019143:Evolution, Molecular; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000737:chemistry* / Q000235:genetics*; D006801:Humans; D009154:Mutation; D010802:Phylogeny; D014157:Transcription Factors
chemical_list: D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D014157:Transcription Factors; C066177:Ubx protein, Drosophila