Cardiopulmonary pathology in primary murine toxocariasis.
The cellular infiltration in the 1st week was marked in group III & II compared to group I. Parts of larvae were encountered more in the group III than in group I & II. Eosinophilic alveolar exudate was detected more in group III in subgroups a, b and c, in group II only in subgroup (a) and not in group I. Lobar pneumonia was reported in subgroups a and b, in group III in subgroup a, in group II and not in group I. Cardiomegaly was reported in 7.1%, 10.7% and 64.2% in group I, II and III respectively. Mechanical traumatic effect of larval migration in group III was more than group II, I. The extensive haemorrhagic areas and diffuse cellular in filtrations and parts of larvae were predominant in subgroup (a) of group III in Granulomata & began to appear in subgroup (c). First, it was diffuse then became circumscribed in pleural and subpleural areas. Haemorrhagic areas in the endocardium was observed in 7.1%, 17.8% and 89.3% in groups I, II and III respectively. Foci of cellular infiltration, diffuse interstitial infiltration, granulomas, thickening of blood vessels, necrosis of cardiac muscle and focal fragmentation of muscle fibers were encountered.
el-Shazly
Atef M
AM
Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
Abdel-Mageed
Salama
S
el-Hamshry
Eman
E
el-Shewy
Khaled
K
Dawoud
Hamdy A
HA
Morsy
Tosson A
TA
D000818:Animals; D004285:Dogs; D006321:Heart / Q000469:parasitology; D007150:Immunohistochemistry; D007814:Larva; D008168:Lung / Q000469:parasitology / Q000473:pathology*; D008297:Male; D051379:Mice; D009206:Myocardium / Q000473:pathology*; D011897:Random Allocation; D017166:Toxocara canis / Q000472:pathogenicity; D014120:Toxocariasis / Q000469:parasitology / Q000473:pathology*