title: PeCoP: automatic determination of persistently conserved positions in protein families.
abstract: PeCoP is a WWW-based service which accepts a protein sequence, and reports positions that are conserved in close and distant sequence family members. The collation of family members is performed using iterative PSI-BLAST runs. Examining positional conservation in close and distant family members enables a better selection of positions that may play a role in determining the protein's structure and function.
  
  
  BACKGROUND
  http://bioinformatics.org/pecop
  
  
  BACKGROUND
  idoerg@burnham.org
  
  
  BACKGROUND
  http://bioinformatics.org/pecop/about_pecop
authors.affiliation: Department of Molecular Genetics and Biotechnology, The Hebrew University--Hadassah Medical School, 91120, Jerusalem, Israel. idoerg@burnham.org
authors.forename: Iddo
authors.initials: I
authors.lastname: Friedberg
authors.forename: Hanah
authors.initials: H
authors.lastname: Margalit
mesh_terms: D000595:Amino Acid Sequence; D017124:Conserved Sequence / Q000235:genetics*; D030562:Databases, Protein; D020407:Internet; D008969:Molecular Sequence Data; D011506:Proteins / Q000145:classification* / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods; D012984:Software
chemical_list: D011506:Proteins