Detecting Repetitive DNA in Eukaryotes.
A detection software of repetitive elements, especially for Alu is designed according to the theory of the correspondence analysis. The results obtained on the test set of 38 gene sequences showed that the true-negative is about 5.8% and false-positive is about 4.8%. Also, the detailed description of Alu elements in the sequences in which the Alu elements are spliced into coding-regions and the successful search for Alu in large-scale T-cell receptor loci sequence showed that the software is a better tool for the recognition of repeat elements.
Chen
Jie
J
Shanghai Institute of Biochemistry, the Chinese Academy of Sciences, Shanghai 200031, China.
Ding
Da-Fu
DF