title: Powerful Claisen condensation and Claisen-aldol tandem reaction of alpha,alpha-dialkylated esters promoted by ZrCl4-iPr2NEt.
abstract: Powerful Claisen ester condensations of alpha,alpha-dialkylated esters mediated by ZrCl4-iPr2NEt were performed to give the corresponding thermodynamically unfavorable alpha,alpha-dialkylated beta-ketoesters, and Claisen-aldol tandem reactions between an intermediary Zr-enolate of a alpha,alpha-dialkylated beta-ketoester and aldehydes also proceeded.
authors.affiliation: School of Science, Kwansei Gakuin University, 1-1-155 Uegahara, Nishinomiya, Hyogo 622-8501, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tanabe
authors.forename: R
authors.initials: R
authors.lastname: Hamasaki
authors.forename: S
authors.initials: S
authors.lastname: Funakoshi