title: Optical imaging of glycinergic inhibition in the vestibular and cochlear nuclei.
abstract: Using multiple-site optical recording techniques, the spatiotemporal activity was observed in both the cochlear and vestibular nucleus in newborn mice. The optical responses were obviously enhanced by bath-applied strychnine. A quantitative analysis showed higher enhancements to occur in the cochlear nucleus than in the vestibular nucleus. Optical imaging enables us to visualize the spatiotemporal extent of the inhibitory receptive field after the application of strychnine.
authors.affiliation: Department of Otolaryngology, Kansai Medical University, Fumizono-cho 10-15, Moriguchi, Osaka 570-8507, Japan.
authors.forename: Shi-Ming
authors.initials: SM
authors.lastname: Yang
authors.forename: Tadashi
authors.initials: T
authors.lastname: Doi
authors.forename: Shen
authors.initials: S
authors.lastname: Jing
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Kaneko
authors.forename: Ayumi
authors.initials: A
authors.lastname: Matsumoto-Ono
authors.forename: Mikiya
authors.initials: M
authors.lastname: Asako
authors.forename: Toshio
authors.initials: T
authors.lastname: Yamashita
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D017626:Cochlear Nucleus / Q000187:drug effects / Q000502:physiology*; D003952:Diagnostic Imaging; D005998:Glycine / Q000502:physiology*; D051379:Mice; D009433:Neural Inhibition / Q000187:drug effects; D013331:Strychnine / Q000494:pharmacology; D009435:Synaptic Transmission / Q000187:drug effects; D014726:Vestibular Nuclei / Q000187:drug effects / Q000502:physiology*
chemical_list: D013331:Strychnine; D005998:Glycine