title: Primary cerebral non-Langerhans cell histiocytosis: MRI and differential diagnosis.
abstract: We report a young woman with primary cerebral non-Langerhans cell histiocytosis of the juvenile xanthogranuloma family. The clinical course was complicated by extensive infiltration of cranial nerves and meninges and epi- and intramedullary spinal dissemination. Whereas the cutaneous form of juvenile xanthogranuloma is usually benign and self-limited, central nervous system involvement is associated with high morbidity and mortality and might therefore be considered a separate clinical entity.
authors.affiliation: Department of Neuroradiology, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, German. ulrike.ernemann@med.uni-tuebingen.de
authors.forename: U
authors.initials: U
authors.lastname: Ernemann
authors.forename: M
authors.initials: M
authors.lastname: Skalej
authors.forename: M
authors.initials: M
authors.lastname: Hermisson
authors.forename: M
authors.initials: M
authors.lastname: Platten
authors.forename: R
authors.initials: R
authors.lastname: Jaffe
authors.forename: K
authors.initials: K
authors.lastname: Voigt
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D003391:Cranial Nerves / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008578:Meninges / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis* / Q000473:pathology