title: MR imaging of neuropathic feet in leprosy patients with suspected osteomyelitis.
abstract: This study was undertaken to analyze MRI findings in leprosy patients with neuropathic feet, which are suspected of having osteomyelitis. As far as we know, there is no literature concerning osteomyelitis and MRI in neuropathic leprosy feet at present. Therefore, we have included MRI examination of 18 events of suspected osteomyelitis in 12 leprosy patients. All patients with long-standing neuropathic foot problems were clinically suspected of having osteomyelitis. All patients underwent the MRI protocol with the inclusion of Two Point Dixon Chemical Shift Imaging as a fat-suppression sequence. For the MRI evaluation, we used signs that are described in literature for detecting osteomyelitis in diabetic feet. The primary MRI signs were positive in 17 of 18 patients. The secondary MRI signs were positive in 100% of the patients. Our results show that MRI with the use of Two Point Dixon Chemical Shift Imaging is a promising diagnostic modality to detect osteomyelitis in the presence of neurosteoarthropathic changes in patients with leprosy. Whenever available, MRI could play an important role in detecting osteomyelitis in leprosy patients with long-standing neuropathic feet.
authors.affiliation: Department of Radiology, Suite G1-231, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam Zuidoost, The Netherlands. m.maas@amc.uva.nl
authors.forename: Mario
authors.initials: M
authors.lastname: Maas
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Slim
authors.forename: Agnes F
authors.initials: AF
authors.lastname: Heoksma
authors.forename: Ad J
authors.initials: AJ
authors.lastname: van der Kleij
authors.forename: Erik M
authors.initials: EM
authors.lastname: Akkerman
authors.forename: Gerard J
authors.initials: GJ
authors.lastname: den Heeten
authors.forename: William R
authors.initials: WR
authors.lastname: Faber
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002481:Cellulitis / Q000175:diagnosis; D005260:Female; D005528:Foot / Q000473:pathology; D005534:Foot Diseases / Q000150:complications* / Q000473:pathology; D006801:Humans; D007918:Leprosy / Q000150:complications*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis*; D010523:Peripheral Nervous System Diseases / Q000150:complications*; D012189:Retrospective Studies; D013639:Tarsal Bones / Q000473:pathology