title: Comparison of the experience with acute and chronic electrically stimulated detrusor myoplasty.
abstract: OBJECTIVE
  To evaluate the acute and chronic urodynamic effects of electrically stimulated detrusor myoplasty in dogs.
  
  
  METHODS
  Eight female mongrel dogs were studied acutely and six dogs chronically (0 to 12 weeks postoperatively). Bladders were wrapped with the rectus abdominis muscle, keeping an intact blood supply and at least two intercostal nerves of the flap preserved. Bladders were electrically stimulated with bipolar electrodes inserted into the muscle. Urodynamics and post void residual were measured post operatively in the acute studies and every 2 weeks for 3 months in chronic studies.
  
  
  RESULTS
  Acutely, the increase in intravesical pressure was 45+/-7 cm H(2)O, which resulted in a postvoid residual of 26+/-3%. In the chronic study, increases of intravesical pressure sufficient to empty the bladder during myoplasty electrical stimulation were not sustained, although detrusor compliance and flap viability were preserved.
  
  
  CONCLUSIONS
  The electrically stimulated detrusor myoplasty worked well acutely to increase vesical pressure sufficient to empty the bladder, but the chronically stimulated myoplasty did not maintain efficient bladder emptying primarily due to electrode problems. Further studies with improved electrode material and placement are required before clinical application of the electrically stimulated detrusor myoplasty can be assessed.
authors.affiliation: Division of Urology, Department of Surgery, University of Louisville School of Medicine, Louisville, Kentucky, USA. jvansavage@regionalurology.com
authors.forename: John G
authors.initials: JG
authors.lastname: Van Savage
authors.forename: Gustavo
authors.initials: G
authors.lastname: Perez-Abadia
authors.forename: Lucio G
authors.initials: LG
authors.lastname: Palanca
authors.forename: Janou W
authors.initials: JW
authors.lastname: Bardoel
authors.forename: Thomas
authors.initials: T
authors.lastname: Harralson
authors.forename: Mohammad
authors.initials: M
authors.lastname: Amin
authors.forename: Martin
authors.initials: M
authors.lastname: Palacio
authors.forename: Gordon
authors.initials: G
authors.lastname: Tobin
authors.forename: Claudio
authors.initials: C
authors.lastname: Maldonado
authors.forename: John H
authors.initials: JH
authors.lastname: Barker
mesh_terms: D000818:Animals; D003187:Compliance; D004285:Dogs; D004558:Electric Stimulation / Q000379:methods*; D005260:Female; D009119:Muscle Contraction; D011312:Pressure; D017568:Rectus Abdominis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013524:Surgical Flaps; D013997:Time Factors; D001743:Urinary Bladder / Q000503:physiopathology* / Q000601:surgery*; D014563:Urodynamics