title: [How I treat...advanced cancer of the pancreas with a novel approach directed against new targets].
abstract: A better knowledge of fundamental mechanisms of carcinogenesis allows the development of novel therapeutic tools specifically targeting the cancer cell. Our understanding of cellular and molecular mechanisms controlling cellular cycle and cell survival is an important step for new anti-cancer treatments. This review will focus on new therapeutic's strategies in advanced pancreatic cancer.
authors.affiliation: Service d'Oncologie médicale, CHU, Sart Tilman.
authors.forename: M
authors.initials: M
authors.lastname: Polus
authors.forename: V
authors.initials: V
authors.lastname: Bours
authors.forename: G
authors.initials: G
authors.lastname: Jerusalem
authors.forename: B
authors.initials: B
authors.lastname: Sautois
authors.forename: G
authors.initials: G
authors.lastname: Fillet
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors* / Q000187:drug effects / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002453:Cell Cycle; D002986:Clinical Trials as Topic; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D066246:ErbB Receptors / Q000187:drug effects / Q000502:physiology*; D051231:Farnesyltranstransferase; D006801:Humans; D020782:Matrix Metalloproteinases / Q000187:drug effects / Q000494:pharmacology; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000187:drug effects / Q000502:physiology
chemical_list: D019883:Alkyl and Aryl Transferases; D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D066246:ErbB Receptors; D051231:Farnesyltranstransferase; D020782:Matrix Metalloproteinases; D018719:Erb-b2 Receptor Tyrosine Kinases