title: Clear cell adenocarcinoma of the urinary bladder inducing acute renal failure.
abstract: We report a case of clear cell adenocarcinoma of the urinary bladder. A 59-year-old male was referred to our hospital complaining of oliguria, left lower abdominal pain and loss of appetite. Ultrasonography revealed bilateral hydroureteronephrosis and obstructions at the ureterovesical junction. Magnetic resonance imaging demonstrated an invasive irregular tumor located in the posterior wall of the urinary bladder and urinary infiltration to the left retroperitoneal space. The clinical diagnosis was acute post renal failure due to bilateral ureteral obstructions from an invasive bladder tumor. After we performed bilateral percutaneous nephrostomy, the patient underwent trans urethral biopsy of the bladder tumor, which showed clear cell adenocarcinoma extending from the submucosa to the muscular layer, histopathologically. The patient died of metastatic disease 8 months after diagnosis. To our knowledge, the present case is the 23rd to be reported and demonstrates the shortest survival period in the related literature.
authors.affiliation: Department of Urology, Kanto Central Hospital, Tokyo, Japan. yoh_m@nibb.ac.jp
authors.forename: Yoh
authors.initials: Y
authors.lastname: Matsuoka
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Machida
authors.forename: Kaoru
authors.initials: K
authors.lastname: Oka
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Ishizaka
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D018262:Adenocarcinoma, Clear Cell / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000150:complications*