title: Lesions of periventricular tissue surrounding the anteroventral third ventricle (AV3V) attenuate salivation and thermal tolerance in response to a heat stress.
abstract: The purpose of this study was to determine if ablation of the periventricular tissue that surrounds the anteroventral third ventricle (AV3V) would reduce an animal's ability to withstand a thermal challenge. The results show that AV3V-lesion rats are less capable of withstanding a 37 degrees C heat stress and that this is, at least in part, due to a reduced salivation response.
authors.affiliation: Department of Physiology and Biophysics, University of Iowa, Iowa City, IA 52242, USA.
authors.forename: Douglas George
authors.initials: DG
authors.lastname: Whyte
authors.forename: Alan Kim
authors.initials: AK
authors.lastname: Johnson
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D001833:Body Temperature Regulation / Q000502:physiology*; D001834:Body Water / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D003714:Denervation; D018882:Heat Stress Disorders / Q000473:pathology / Q000503:physiopathology*; D006706:Homeostasis / Q000502:physiology; D006358:Hot Temperature / Q000009:adverse effects; D008297:Male; D009434:Neural Pathways / Q000502:physiology; D011301:Preoptic Area / Q000473:pathology / Q000503:physiopathology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012472:Salivation / Q000502:physiology*; D020542:Third Ventricle; D014882:Water-Electrolyte Balance / Q000502:physiology