[Arterial pressure in the orbital artery and eye perfusion in patients with different stages of primary open-angle glaucoma].
A total of 902 patients aged 40-82 years (1804 eyes) with primary open-angle glaucoma (POAG) with different stages of the disease and different intraocular pressure (IOP) and systemic arterial pressure (AP) 105-170 mm Hg were examined. Control group consisted of 340 age-matched normal subjects (680 eyes) with the same values of AP. Systemic AP affected the mean dynamic and perfusion pressure (Pm.ophth. and Pperf.) in both normal subjects and patients with POAG. In addition, both parameters in POAG patients depended on IOP and duration of the glaucomatous process. An increase of IOP was paralleled by a compensatory increase of Pm.ophth., but the higher IOP (an increase within the b-c interval), the less pronounced the increase of Pm.ophth., particularly in patients with well-developed and advanced stages. A progressive decrease of Pperf. was observed, which was related to high IOP and duration of the glaucomatous process.
Kunin
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D005123:Eye / Q000098:blood supply*; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D008875:Middle Aged; D008954:Models, Biological; D009880:Ophthalmic Artery / Q000502:physiology*; D013997:Time Factors