title: Laparoscopic radical prostatectomy: a European virus with global potentials.
abstract: OBJECTIVE
  To review the current status of the Laparoscopic Radical Prostatectomy in Europe (LRP).
  
  
  METHODS
  The published peer reviewed articles on the experience of the European groups performing Laparoscopic Radical Prostatectomy.
  
  
  RESULTS
  Three different approaches have been described for LRP, two of them transperitoneally (early dissection of seminal vesicles or of the prostatic apex) and one totally extra peritoneally. Results in terms of per operative performances and immediate outcomes seem to be comparable with the exception of the bleeding and the transfusion rate that seem higher in the transperitoneal approach with early dissection of the prostatic apex. Conversion rates have been described up to 5% but it is rare after the 20 first cases; after the learning curve has been overcome the complication rate varies between 10% and 17%. Being a novel technique, all the series have a short median follow-up of around one year. The one-year continence rates are comparable to the ones described with the classical open approach, as it is the potency rate. The rate of positive margins bounces between 2 and 49% depending mainly on case selection. A long and steady learning curve burdens the technique in terms of complications.
  
  
  CONCLUSIONS
  LRP is feasible, teachable and reproducible. Although no comparative series with the open approach are available yet, functional and oncological results seem to be comparable to the ones reached after open Retropubic Radical Prostatectomy.
authors.affiliation: Centre for Minimal Invasive Urology and Laparoscopy, UMC St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Jdelarosette@uro.azn.nl
authors.forename: Jean J M C H
authors.initials: JJ
authors.lastname: De La Rosette
authors.forename: Claude C
authors.initials: CC
authors.lastname: Abbou
authors.forename: Jens
authors.initials: J
authors.lastname: Rassweiler
authors.forename: M Pilar
authors.initials: MP
authors.lastname: Laguna
authors.forename: Claude C
authors.initials: CC
authors.lastname: Schulman
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D016063:Blood Loss, Surgical; D001803:Blood Transfusion / Q000706:statistics & numerical data; D003714:Denervation; D004059:Diffusion of Innovation; D007172:Erectile Dysfunction / Q000453:epidemiology / Q000209:etiology; D005060:Europe; D005069:Evaluation Studies as Topic; D005500:Follow-Up Studies; D005837:Genitalia, Male / Q000294:innervation; D006470:Hemorrhage / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D009366:Neoplasm Seeding; D011183:Postoperative Complications / Q000453:epidemiology; D011467:Prostate / Q000601:surgery; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology / Q000601:surgery*; D012669:Seminal Vesicles / Q000601:surgery; D016896:Treatment Outcome