Inhibition of hemolytic activity of Aeromonas salmonicida GCAT in rainbow trout red blood cells by a monoclonal antibody.
The present study shows that a monoclonal antibody (MAb) directed to Aeromonas salmonicida glycerophospholipid:cholesterol acyltransferase (GCAT) is capable of protecting rainbow trout red blood cells from the cytotoxic effects of the enzyme in vitro.
Lachmann
Ingolf
I
Institute for Zoology, University of Leipzig, Germany. ilachman@gmx.de
Droessler
Karl
K
D000217:Acyltransferases / Q000276:immunology*; D000333:Aeromonas / Q000201:enzymology / Q000276:immunology*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D004912:Erythrocytes / Q000201:enzymology*; D005393:Fish Diseases / Q000276:immunology / Q000382:microbiology; D016905:Gram-Negative Bacterial Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary; D006461:Hemolysis; D017686:Oncorhynchus mykiss / Q000097:blood*
D000911:Antibodies, Monoclonal; D000217:Acyltransferases; C020597:glycerophospholipid-cholesterol acyltransferase