title: Antimicrobial susceptibility of coagulase-negative staphylococci isolated from bovine mastitis in Argentina.
abstract: A total of 123 isolates of coagulase-negative staphylococci isolated from bovine clinical and subclinical mastitis in Argentina from March 1998 to March 2000 was investigated for in vitro susceptibility to several antimicrobial agents. Minimum inhibitory concentrations that inhibit 90% of the isolates tested (reported in micrograms per milliliter) were: 4.40, 0.38, 4.00, 0.75, 0.75, 3.60, and 2.00 for penicillin, oxacillin, cephalothin, gentamicin, erythromycin, clindamycin, and ampicillin-sulbactam, respectively. Resistance was detected in 34 (27.6%), 4 (3.2%), 7 (5.7%), and 6 (4.8%) isolates for penicillin, oxacillin, erythromycin, and pirlimycin, respectively. No resistance was detected for gentamicin, cephalothin, or ampicillin-sulbactam. Results indicated that coagulase-negative staphylococci isolates in Argentina exhibited the highest degree of resistance to penicillin of all antimicrobial agents tested.
authors.affiliation: Departamento de Fisiopatología y Etiopatogenia, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Argentina.
authors.forename: E
authors.initials: E
authors.lastname: Gentilini
authors.forename: G
authors.initials: G
authors.lastname: Denamiel
authors.forename: A
authors.initials: A
authors.lastname: Betancor
authors.forename: M
authors.initials: M
authors.lastname: Rebuelto
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez Fermepin
authors.forename: R A
authors.initials: RA
authors.lastname: De Torrest
mesh_terms: D000667:Ampicillin / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001118:Argentina; D002417:Cattle; D002512:Cephalothin / Q000494:pharmacology; D002981:Clindamycin / Q000031:analogs & derivatives* / Q000494:pharmacology; D003030:Coagulase / Q000032:analysis*; D024881:Drug Resistance, Bacterial; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D005839:Gentamicins / Q000494:pharmacology; D008414:Mastitis, Bovine / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D008892:Milk / Q000382:microbiology; D010068:Oxacillin / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects* / Q000201:enzymology; D013407:Sulbactam / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D003030:Coagulase; D005839:Gentamicins; D010406:Penicillins; D002981:Clindamycin; D004917:Erythromycin; C035444:sultamicillin; D000667:Ampicillin; C034093:pirlimycin; D002512:Cephalothin; D013407:Sulbactam; D010068:Oxacillin