title: [Quantitative cartilage analysis with magnetic resonance tomography (qMRI)--a new era in arthrosis diagnosis?].
abstract: Magnetic resonance imaging (MRI) is a new and very powerful method for the diagnostics and monitoring of osteoarthritis. Its advantage is that all articular tissues can be visualized directly and are accessible for three-dimensional analysis. This article reviews qualitative, semi-quantitative, and quantitative studies on articular cartilage with MRI. In particular we discuss pulse sequences and three-dimensional postprocessing methods for quantitative analysis of cartilage volume and thickness, along with their accuracy and precision in healthy volunteers and patients with osteoarthritis. It addition, we present approaches for quantitative analyses of structural/biochemical parameters and for the deformational behavior of cartilage in vivo.
authors.affiliation: Forschungsgruppe Muskuloskelettales System Anatomische Anstalt Ludwig-Maximilians-Universität München Pettenkoferstr. 11, 80336 München, Germany. eckstein@anat.med.uni-muenchen.de
authors.forename: F
authors.initials: F
authors.lastname: Eckstein
authors.forename: K H
authors.initials: KH
authors.lastname: Englmeier
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D002358:Cartilage, Articular / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D020370:Osteoarthritis, Knee / Q000175:diagnosis*; D012680:Sensitivity and Specificity