title: [Effects of cordyceps sinensis on T lymphocyte subsets and hepatofibrosis in patients with chronic hepatitis B].
abstract: In order to find an effective drug to cure patients with chronic hepatitis B, cordyceps sinensis had been used to treat 25 patients with chronic hepatitis B. The comprehensive index, including T lymphocyte subsets (CD4, CD8), hyaluronic acid(HC) and precollagen type III(PC III), were observed before and after treatment. After 3 months of treatment, CD4 and CD4/CD8 ratio increased significantly(P < 0.05), while HA and PC III decreased significantly(P < 0.05) compared with the control. The results suggest that the beneficial effects might be obtained by using cordyceps sinensis to adjust the T lymphocyte subsets level and to treat hepatic fibrosis on patients with chronic hepatitis B.
authors.affiliation: Department of Infectious Disease, Third Affiliated Hospital, Hunan Medical University, Changsha 410013.
authors.forename: H Y
authors.initials: HY
authors.lastname: Gong
authors.forename: K Q
authors.initials: KQ
authors.lastname: Wang
authors.forename: S G
authors.initials: SG
authors.lastname: Tang
mesh_terms: D000293:Adolescent; D000328:Adult; D016516:CD4-CD8 Ratio; D024061:Collagen Type III / Q000097:blood; D032661:Cordyceps / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D019694:Hepatitis B, Chronic / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D006801:Humans; D006820:Hyaluronic Acid / Q000097:blood; D008103:Liver Cirrhosis / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D016176:T-Lymphocyte Subsets / Q000276:immunology*
chemical_list: D024061:Collagen Type III; D004365:Drugs, Chinese Herbal; D006820:Hyaluronic Acid