The development of contraceptive vaccines.
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning. However, only this one Phase II trial has been completed despite a plethora of hormonal and gamete antigens that have been proposed as candidate vaccines. Improvements in the design and formulation of contraceptive vaccines are underway and will be a necessary prelude to further clinical trials.
Delves
Peter J
PJ
Department of Immunology and Molecular Pathology, Windeyer Institute of Medical Sciences, University College London, UK. p.delves@ucl.ac.uk
D000818:Animals; D017322:Clinical Trials, Phase II as Topic / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D013678:Technology, Pharmaceutical / Q000379:methods*; D022642:Vaccines, Contraceptive / Q000276:immunology / Q000494:pharmacology*
D022642:Vaccines, Contraceptive