title: [A case of invasive Clostridium perfringens infection complicated intravascular hemolysis].
abstract: We experience a case of a 83-year-old male who was admitted complaining of chills, cramp, high fever and respiratory distress. His blood revealed marked hemolysis. Gram positive Rods was observed in the hemoliesed blood taken on admission. About 2 hours after admission, he suddenly fell into a critical condition. He died about 6 hours after admission in spite of resuscitation. Clostridium perfringens was detected from the blood and liver obtained by autopsy. We suspected that he died of acute intravascular hemolysis caused by alpha-toxin produced by C. perfringens. In conclusion, for a patient who has a high fever with strong hemolysis such as our case, C. perfringens infection should be considered.
authors.affiliation: First Division of Clinical Laboratories, Tokyo Metropolitan Police Hospital.
authors.forename: Junko
authors.initials: J
authors.lastname: Fukuhara
authors.forename: Masakazu
authors.initials: M
authors.lastname: Kouda
authors.forename: Shoko
authors.initials: S
authors.lastname: Homma
authors.forename: Chie
authors.initials: C
authors.lastname: Monma
authors.forename: Yoshitoki
authors.initials: Y
authors.lastname: Yanagawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003015:Clostridium Infections / Q000150:complications*; D003016:Clostridium perfringens; D006461:Hemolysis; D006801:Humans; D008297:Male