Protein-losing cytomegalovirus gastritis in a patient with Stevens-Johnson syndrome.
We present a case of protein-losing cytomegalovirus gastritis in a previously immunocompetent 14-year-old Japanese girl that occurred during treatment of drug (zonisamide)-induced Stevens-Johnson syndrome with hepatic failure. Her hepatic failure and symptoms of Stevens-Johnson syndrome were successfully treated with intravenous prednisolone and infusion of fresh-frozen plasma or albumin, as the occasion demanded. However, during the course of treatment, she complained of severe epigastralgia together with hypoproteinemia, and cytomegalovirus gastritis was found by endoscopic and histological examinations. The possible mechanism by which cytomegalovirus gastritis occurred in the present case and effective diagnostic procedures are discussed.
Yoshioka
Mikio
M
Department of Pediatrics, Hokkaido University School of Medicine, Sapporo, Japan.
Ishiguro
Nobuhisa
N
Ma
Xiaoming
X
Kikuta
Hideaki
H
Kodaira
Junichi
J
Itoh
Tomoo
T
Kobayashi
Kunihiko
K
D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005756:Gastritis / Q000150:complications* / Q000382:microbiology; D005773:Gastroscopy; D006801:Humans; D007121:Immunocompetence; D007555:Isoxazoles / Q000009:adverse effects*; D011504:Protein-Losing Enteropathies / Q000150:complications* / Q000175:diagnosis; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000150:complications*; D000078305:Zonisamide
D000927:Anticonvulsants; D007555:Isoxazoles; D000078305:Zonisamide