Obesity, aerobic exercise, and vascular disease: the role of oxidant stress.
Oxidant formation in the vasculature contributes to vascular disease and dysfunction associated with obesity. In contrast, exercise-dependent production of oxidants may stimulate adaptive responses that protect against the development of such diseases. In this review, we discuss current concepts in the biology of reactive oxygen and nitrogen species and how their function is modulated in the context of vascular disease, obesity, and aerobic exercise.
Fenster
Catherine P
CP
Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Weinsier
Roland L
RL
Darley-Usmar
Victor M
VM
Patel
Rakesh P
RP
D000818:Animals; D001161:Arteriosclerosis; D003920:Diabetes Mellitus; D015444:Exercise; D006801:Humans; D006973:Hypertension; D009765:Obesity; D018384:Oxidative Stress; D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species; D014652:Vascular Diseases
D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species