title: Palladium catalysed 3-component cascade synthesis of bis(2-arylallyl) tertiary amines from aryl iodides, allene and primary amines.
abstract: A 3-component cascade synthesis of bis(2-arylallyl) tertiary amines from aryl iodide, allene and primary aliphatic amines is described; chiral amines give analogous products with no detectable racemisation; mixtures of two different aryl iodides can be utilised to give the mixed tertiary amines as the sole, or major, product; the reaction is sensitive to stereoelectronic effects which lead to mono(2-arylallyl) secondary amines.
authors.affiliation: Molecular Innovation, Diversity and Automated Synthesis (MIDAS) Centre, School of Chemistry, Leeds University, Leeds, UK LS2 9JT.
authors.forename: X
authors.initials: X
authors.lastname: Gai
authors.forename: R
authors.initials: R
authors.lastname: Grigg
authors.forename: S
authors.initials: S
authors.lastname: Collard
authors.forename: J E
authors.initials: JE
authors.lastname: Muir