A convenient imino aldol reaction in ethyl alcohol catalyzed by a cation-exchange resin.
Imino aldol reaction of ketene silyl acetals with imines proceeds smoothly to give beta-amino esters in good yields under the influence of a cation-exchange resin in ethanol, and the work-up of the reaction consists only of a simple filtration followed by concentration of the crude mixture and purification.
Shimizu
M
M
Department of Chemistry for Materials, Mie University, Tsu, Mie 514-8507, Japan.
Itohara
S
S
Hase
E
E