[Role of the interferon system in the course of neglected forms of colorectal cancer].
Operations for neglected forms of colorectal carcinoma were performed on 66 patients. The interferon status was determined before the operation, on the 1st, 7th and 14th days after the operative intervention. "Viferon-2" was given to 18 patients (starting from 2 days before the operation) with the daily dose 1,000,000 IU. The investigation has shown that deep inhibition of production of interferon (alpha and beta by leukocytes increased risk of the development of postoperative pyo-inflammatory complications. Using the preparation "Viferon-2" is highly effective for prevention of such complications.
Zubarev
P N
PN
Ignatovich
I G
IG
Lazutkin
M V
MV
Arinenko
R Iu
RIu
Anikin
V B
VB
D015179:Colorectal Neoplasms / Q000097:blood / Q000276:immunology* / Q000601:surgery; D005260:Female; D006801:Humans; D007372:Interferons / Q000008:administration & dosage / Q000096:biosynthesis / Q000097:blood; D008297:Male; D008875:Middle Aged
D007372:Interferons