[Characteristics of the post-traumatic reparative process in the M. soleus of rats subjected to extended suspension].
Histological methods were applied to study the course of post-traumatic reparation of m. soleus in rats subjected to a 30-d head-down suspension. Muscles in unconscious animals were traumatized on day 15 of suspension by crushing a small part with the artery clamp. Deprivation of the support loading led to development of muscle atrophy so that mass of the muscle in sacrificed animals was by 53.7% less as compared to the controls. It was shown that reparation phases in the atrophied muscles were not upset; however, the absolute size of the reparation field was significantly less when compared with the control animals. whereas its relative size was similar to the control. This kind of phenomenon is ascribed to the prevalence of catabolic processes in compromised muscles and consequent decline in production of myoblasts and the connective tissue which forms the frame of the reparative field.
Il'ina-Kakueva
E I
EI
Loginov
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VI
D000818:Animals; D018475:Head-Down Tilt; D008297:Male; D018482:Muscle, Skeletal / Q000293:injuries* / Q000378:metabolism / Q000473:pathology / Q000502:physiology; D009133:Muscular Atrophy / Q000209:etiology* / Q000503:physiopathology; D051381:Rats; D017208:Rats, Wistar; D012038:Regeneration; D013997:Time Factors