title: Bleeding from endometrial and vaginal malignant tumors treated with activated recombinant factor VII.
abstract: The authors report two cases of successful employment of human recombinant activated factor VII in gynecological oncological patients (endometrial cancer and vaginal sarcoma) without pre-existing coagulopathy. They conclude that recombinant factor VIIa may be an important and effective drug in severe bleeding in gynecological oncology.
authors.affiliation: Department of Gynecology and Obstetrics, Karol Marcinkowski University of Medical Sciences, Poznan, Poland. Kgo@gpsk.am.poznan.pl
authors.forename: S
authors.initials: S
authors.lastname: Sajdak
authors.forename: R
authors.initials: R
authors.lastname: Moszynski
authors.forename: T
authors.initials: T
authors.lastname: Opala
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000532:radiotherapy; D000282:Administration, Intravaginal; D000328:Adult; D000368:Aged; D016889:Endometrial Neoplasms / Q000150:complications / Q000532:radiotherapy; D004979:Ethamsylate / Q000008:administration & dosage; D005168:Factor VII Deficiency / Q000150:complications / Q000188:drug therapy*; D015942:Factor VIIa / Q000008:administration & dosage*; D005260:Female; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D007262:Infusions, Intravenous; D008339:Mandibular Neoplasms / Q000150:complications / Q000556:secondary / Q000628:therapy; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011994:Recombinant Proteins; D012509:Sarcoma / Q000150:complications / Q000556:secondary / Q000628:therapy; D014148:Tranexamic Acid / Q000008:administration & dosage; D014592:Uterine Hemorrhage / Q000188:drug therapy* / Q000209:etiology*; D014625:Vaginal Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy
chemical_list: D006490:Hemostatics; D011994:Recombinant Proteins; D004979:Ethamsylate; D014148:Tranexamic Acid; D015942:Factor VIIa