title: Central precocious puberty in girls with Williams syndrome.
abstract: We report an estimated prevalence of precocious puberty of 1 in 5 to 6 girls with Williams syndrome (18.3%). Mean menarcheal age of 86 girls with Williams syndrome was 11.5 +/- 1.7 (+/-SD) years. Distribution of menarcheal age was significantly different from that in normal girls (12.9 +/- 1.1 years; n = 759).
authors.affiliation: University Hospital Kiel, Christian-Albrechts-Universität zu Kiel, Germany.
authors.forename: Carl-Joachim
authors.initials: CJ
authors.lastname: Partsch
authors.forename: Insa
authors.initials: I
authors.lastname: Japing
authors.forename: Reiner
authors.initials: R
authors.lastname: Siebert
authors.forename: Angela
authors.initials: A
authors.lastname: Gosch
authors.forename: Armin
authors.initials: A
authors.lastname: Wessel
authors.forename: Wolfgang G
authors.initials: WG
authors.lastname: Sippell
authors.forename: Rainer
authors.initials: R
authors.lastname: Pankau
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D016022:Case-Control Studies; D002648:Child; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015995:Prevalence; D011629:Puberty, Precocious / Q000453:epidemiology / Q000209:etiology*; D018709:Statistics, Nonparametric; D018980:Williams Syndrome / Q000150:complications*