Choriocarcinoma with diffuse intraabdominal abscess and disseminated intravascular coagulation. A case report.
BACKGROUND
Management of choriocarcinoma complicated by diffused intraabdominal abscess is difficult, especially when disseminated intravascular coagulation (DIC) ensues.


METHODS
A 29-year-old woman presented with massive vaginal bleeding, fever and severe abdominal pain. Choriocarcinoma with pulmonary and vaginal metastases was diagnosed along with diffused intraabdominal abscess. Hysterectomy and hypogastric artery ligation were performed after the fever and abdominal symptoms failed to respond to intravenous antibiotics. Although the patient developed DIC after surgery, transfusion, antibiotics and immediate combination chemotherapy improved her condition and controlled the malignancy. She was free of disease for > 20 months after treatment.


CONCLUSIONS
Timely surgery, aggressive antibiotics and immediate postoperative chemotherapy are recommended for patients with choriocarcinoma complicated by intraabdominal abscess and DIC.
Chao
Angel
A
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Department of Anatomic Pathology, Chang Gung Memorial Hospital Linkou Medical Center, Taoyuan, Taiwan.
Lin
Chen-Tao
CT
Chang
Ting-Chang
TC
Hsueh
Swei
S
Lai
Chyong-Huey
CH
D018784:Abdominal Abscess / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D000328:Adult; D002822:Choriocarcinoma / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D004211:Disseminated Intravascular Coagulation / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000150:complications* / Q000473:pathology* / Q000601:surgery