Asymmetric pharyngeal-cervical-brachial weakness associated with anti-GT1a IgG antibody.
We report a case of markedly asymmetric pharyngeal-cervical-brachial weakness. Acute progression of symptoms, albuminocytologic dissociation in cerebrospinal fluid, electrophysiologic evidence of demyelination and elevation of IgG anti-GT1 a antibody titer paralleled the clinical course, support the diagnosis of Guillain-Barré syndrome. Guillain-Barré syndrome should be considered in the differential diagnosis of cranial neuropathy, even in cases where there is marked asymmetry.
Osaki
Y
Y
Department of Medicine & Geriatrics, Kochi Medical School, Nankoku, Kochi, Japan. yosaki@kochi-ms.ac.jp
Koga
M
M
Matsubayashi
K
K
Yuki
N
N
D000208:Acute Disease; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008297:Male; D018908:Muscle Weakness / Q000175:diagnosis* / Q000276:immunology* / Q000503:physiopathology; D009333:Neck / Q000503:physiopathology*; D010291:Paresis / Q000175:diagnosis* / Q000276:immunology* / Q000503:physiopathology; D010614:Pharynx / Q000503:physiopathology*
D001323:Autoantibodies; D007074:Immunoglobulin G