Angiocentric immunoproliferative lesion of the lung.
Angiocentric immunoproliferative lesion (AIL) is the angiocentric and angiodestructive process of lymphoreticular cells with vascular invasion. AIL of the lung is rare. We treated a 57-year-old woman with AIL of the lung in whom chest radiography and computed tomography showed ground-glass opacity in the left lower lobe and lingular segment. Since macroscopical and intraoperative lung biopsy findings could not rule out the possibility of malignancy, including malignant lymphoma, we conducted left pneumonectomy. Immunohistological examination of the tumor showed that infiltrating lymphocytes consistent with AIL. Because tumor markers such as serum LDH and soluble IL-2 receptor increased postoperatively, we conducted systemic chemotherapy, after which elevated serum tumor markers decreased.
Ichiki
Yoshinobu
Y
Department of Surgery II, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.
Osaki
Toshihiro
T
Yamashita
Tomohiro
T
Oyama
Tsunehiro
T
Sugio
Kenji
K
Yasumoto
Kosei
K
D005260:Female; D006801:Humans; D007160:Immunoproliferative Disorders / Q000473:pathology* / Q000628:therapy; D008171:Lung Diseases / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged