title: Secretion of natriuretic peptides caused by an epileptic attack.
abstract: OBJECTIVE
  To describe clinical features of a patient with secretions of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) during an epileptic attack.
  
  
  METHODS
  A 65-year-old woman experienced frequent bouts of polyuria, pyrexia and general fatigue after several years of a cerebral contusion involving the left fronto-temporal lobe caused by a traffic accident. Her urine output and urinary sodium excretion increased, and plasma ANP and BNP concentrations were markedly high during each attack. Electroencephalography (EEG) showed serial seizure discharge in the left anterior temporal region during the attacks, indicative of epileptic focus.
  
  
  CONCLUSIONS
  ANP and BNP secretions probably were triggered by epileptic stimulation on the diencephalon beyond the focus.
authors.affiliation: Department of Neurology, National Shizuoka Hospital, Shizuoka, Japan. obit@szec.hosp.go.jp
authors.forename: T
authors.initials: T
authors.lastname: Obi
authors.forename: M
authors.initials: M
authors.lastname: Takatsu
authors.forename: T
authors.initials: T
authors.lastname: Konishi
authors.forename: K
authors.initials: K
authors.lastname: Mizoguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Nishimura
mesh_terms: D000368:Aged; D009320:Atrial Natriuretic Factor / Q000097:blood*; D006259:Craniocerebral Trauma / Q000150:complications; D004231:Diuresis; D004569:Electroencephalography; D004834:Epilepsy, Post-Traumatic / Q000097:blood* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D012964:Sodium / Q000652:urine; D013702:Temporal Lobe / Q000473:pathology
chemical_list: D020097:Natriuretic Peptide, Brain; D009320:Atrial Natriuretic Factor; D012964:Sodium