title: Malignant sacrococcygeal yolk sac (endodermal sinus) tumor.
abstract: We report a 2 1/2 years old female child who presented with Malignant Sacrococcygeal Yolk sac (Endodermal Sinus) tumor as presacral mass with ulceration of overlying skin. Her ultrasonography (USG)abdomen revealed a huge presecral mass with irregular margins extending in to the pelvis, pushing the rectum antero-laterally. CT scanning of abdomen confirmed USG finding with out enlargement of retroperitoneal lymph nodes and no involvement of the liver. Serum AFP was abnormally elevated. The tumor was excised along with Coccyx in-toto through posterior approach dividing the sacrum and 3-Drugs (VAC) Chemotherapy started postoperatively i.e. 2-weeks after surgery. Here we discuss our experience with this extremely rare malignant extra-gonadal germ-cell tumor and review of literature.
authors.affiliation: Departments of Surgery, Oncology, Ayub Teaching Hospital, Abbottabad.
authors.forename: Tariq
authors.initials: T
authors.lastname: Mufti
authors.forename: M Saeed
authors.initials: MS
authors.lastname: Khan
authors.lastname: Muzher-U-Dua
authors.forename: Farah
authors.initials: F
authors.lastname: Waqar
mesh_terms: D002675:Child, Preschool; D018240:Endodermal Sinus Tumor / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D005260:Female; D006801:Humans; D012445:Sacrococcygeal Region