[Purpura fulminans. A fatal consequence of a widely used medication?].
A 39-year old man developed purpura fulminans, a manifestation of disseminated intravascular coagulopathy, with rhabdomyolsis following the i.m. injection of diclofenac.
Hengge
U R
UR
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Essen, Germany. ulrich.hengge@uni-esen.de
Jochum
C
C
Tschakarjan
E
E
Maschke
J
J
Erbel
R
R
Schmid
K W
KW
Otterbach
F
F
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D004008:Diclofenac / Q000008:administration & dosage / Q000009:adverse effects*; D004211:Disseminated Intravascular Coagulation / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D003875:Drug Eruptions / Q000175:diagnosis* / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D011695:IgA Vasculitis / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D007251:Influenza, Human / Q000188:drug therapy*; D007273:Injections, Intramuscular; D008297:Male; D012867:Skin / Q000473:pathology; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac