title: Effect of germanium, poly-trans-[2-carboxyethyl] germasesquioxane on natural killer (NK) activity in dogs.
abstract: In an attempt to study the immunological effects on normal and adenocarcinoma (AC) dogs, the natural killer (NK) activity was determined. Augmentation of NK cell activities in responsive normal and AC dogs that indicatedanergy in the phaseolus vulgaris agglutinin (PHA) skin-test was manifested when the animals were accordingly treated with germanium (GN).
authors.affiliation: Department of Veterinary Medicine, Nihon University College of Bioresonance Sciences, Fujisawa, Kanagawa, Japn.
authors.forename: Masato
authors.initials: M
authors.lastname: Kuwabara
authors.forename: Shigeo
authors.initials: S
authors.lastname: Ohba
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yukawa
mesh_terms: D000230:Adenocarcinoma / Q000276:immunology / Q000662:veterinary*; D000284:Administration, Oral; D000818:Animals; D003601:Cytotoxicity Tests, Immunologic; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs; D005857:Germanium / Q000008:administration & dosage / Q000494:pharmacology*; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D011868:Radioisotopes
chemical_list: D011868:Radioisotopes; D005857:Germanium