title: Effects of acute mild and moderate hypoxia on human mood state.
abstract: OBJECTIVE
  To explore the effects of acute mild and moderate hypoxia on human mood state.
  
  
  METHODS
  The mood states of 18 healthy male volunteers were evaluated by self-assessment questionnaires, profile of mood state (POMS) and state anxiety inventory (S-AI) after random exposure to simulated altitude of 300 m (control), 2800 m, 3600 m and 4400 m for 1 h in a hypobaric chamber.
  
  
  RESULTS
  The data at 300 m level were taken as the baseline control. The negative mood state factor points (tension, fatigue etc.) increased gradually as the altitude level increased while V (vigor-activity) points had a tendency to decrease (P<0.05 or P<0.01). No significant difference was found in the points of (D, A) even under exposure to 4400 m (P>0.05). At the early period of 2800 m exposure the tension points of POMS and S-AI scores were higher than those of control level (P<0.05) then dropped to baseline level when exposure to this altitude for 1 h.
  
  
  CONCLUSIONS
  Exposure to acute mild hypobaric hypoxia at 2800 m for 1 h has adverse effect on mood state of healthy person and the negative effect was further aggravated with the increment of altitude level.
authors.affiliation: Department of Aerospace Medicine (DAM), Fourth Military Medical University, Xi'an.
authors.forename: X Y
authors.initials: XY
authors.lastname: Li
authors.forename: X Y
authors.initials: XY
authors.lastname: Wu
authors.forename: C
authors.initials: C
authors.lastname: Fu
authors.forename: X F
authors.initials: XF
authors.lastname: Shen
authors.forename: Y H
authors.initials: YH
authors.lastname: Wu
authors.forename: T
authors.initials: T
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000337:Aerospace Medicine; D000339:Affect; D000531:Altitude; D001007:Anxiety; D001273:Atmosphere Exposure Chambers; D001274:Atmospheric Pressure; D001359:Aviation; D002681:China; D006801:Humans; D000860:Hypoxia / Q000523:psychology*; D008297:Male; D008889:Military Personnel / Q000523:psychology; D011581:Psychological Tests; D011795:Surveys and Questionnaires