title: [Ocular sarcoidosis].
abstract: Ocular involvement of sarcoidosis is frequent, and it is often the initial clinical manifestation of the disease. The most common ocular lesions include granulomatous uveitis associated with iris and trabecular nodules, string of pearl-type vitreous opacities, retinal paerivasculitis mainly affecting veins, and patchy retino-choroidal exudates. A half of the patients with typical ocular lesions suggestive of sarcoidosis did not show the systemic evidence, and they remained as sarcoidosis suspects. Risks of visual deterioration are secondary glaucoma, vitreous opacities, cystoid macular edema, and retinal neovascularization. Thirty-four % of the patients were treated with systemic corticosteroids, and some patients required other treatment such as methotraxate. Twenty-one% of the patients resulted in the poor visual acuity of less that 0.5.
authors.affiliation: Department of Ophthalmology, Nippon Medical School.
authors.forename: Kunitoshi
authors.initials: K
authors.lastname: Ohara
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005123:Eye / Q000473:pathology; D005128:Eye Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D011379:Prognosis; D012507:Sarcoidosis / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D013256:Steroids
chemical_list: D000893:Anti-Inflammatory Agents; D013256:Steroids; D008727:Methotrexate