title: Multiple hypoechoic hepatic lesions in a patient with Gaucher disease.
abstract: The most common symptoms of Gaucher disease include hepatosplenomegaly and anemia and thrombocytopenia due to hypersplenism. We describe the case of a patient with Gaucher disease who had cachexia, massive hepatomegaly, and multiple focal hepatic lesions. The clinical and radiologic findings suggested malignancy. A biopsy specimen was taken from a hepatic lesion and revealed infiltration by Gaucher cells. We discuss our findings in light of the putative increased incidence of hematologic malignancies in patients with Gaucher disease.
authors.affiliation: Department of Radiology, Shaare Zedek Medical Center, Jerusalem, Israel.
authors.forename: Michael
authors.initials: M
authors.lastname: Patlas
authors.forename: Irith
authors.initials: I
authors.lastname: Hadas-Halpern
authors.forename: Constantin
authors.initials: C
authors.lastname: Reinus
authors.forename: Ari
authors.initials: A
authors.lastname: Zimran
authors.forename: Deborah
authors.initials: D
authors.lastname: Elstein
mesh_terms: D000328:Adult; D005260:Female; D005776:Gaucher Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology; D008107:Liver Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography