Efficient preparation of c(2)-symmetrical chiral ferrocenyl diols by catalytic enantioselective reduction of diacylferrocenes.
[reaction: see text] Enantioselective borohydride reduction, catalyzed by the optically active beta-ketoiminato cobalt(II) complex, was successfully applied to the 1,1'-dialkanoyl- and 1,1'-dibenzoylferrocenes to afford the corresponding C(2)-symmetrical chiral ferrocenyl diols with high diastereoselectivity and excellent enantioselectivity.
Sato
Hirohide
H
Department of Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
Watanabe
Hiroto
H
Ohtsuka
Yuhki
Y
Ikeno
Taketo
T
Fukuzawa
Shin-Ichi
S
Yamada
Tohru
T