Spatiotemporal pattern of neural processing in the human auditory cortex.
The principles that the auditory cortex uses to decipher a stream of acoustic information have remained elusive. Neural responses in the animal auditory cortex can be broadly classified into transient and sustained activity. We examined the existence of similar principles in the human brain. Sound-evoked, blood oxygen level-dependent signal response was decomposed temporally into independent transient and sustained constituents, which predominated in different portions-core and belt-of the auditory cortex. Converging with unit recordings, our data suggest that this spatiotemporal pattern in the auditory cortex may represent a fundamental principle of analyzing sound information.
Seifritz
Erich
E
Department of Psychiatry, University of Basel, 4025 Basel, Switzerland. erich.seifritz@unibas.ch
Esposito
Fabrizio
F
Hennel
Franciszek
F
Mustovic
Henrietta
H
Neuhoff
John G
JG
Bilecen
Deniz
D
Tedeschi
Gioacchino
G
Scheffler
Klaus
K
Di Salle
Francesco
F
D000161:Acoustic Stimulation; D000328:Adult; D000818:Animals; D001303:Auditory Cortex / Q000166:cytology / Q000502:physiology*; D001306:Auditory Pathways / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009474:Neurons / Q000502:physiology*; D010100:Oxygen / Q000097:blood
D010100:Oxygen