Mechanisms underlying atrioventricular nodal conduction and the reentrant circuit of atrioventricular nodal reentrant tachycardia using optical mapping.
The findings of multiple nondiscrete AV nodal pathways and asymmetric transitional zone provide a biophysical basis for understanding normal and abnormal AV node electrophysiology. Unidirectional block occurring at the transitional zone transforms the nondiscrete pathways model into a classic dual pathways physiology for AVNRT.
Wu
Jianyi
J
Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis 46202, USA. wuj@iupui.edu
Zipes
Douglas P
DP
D000200:Action Potentials / Q000502:physiology; D001283:Atrioventricular Node / Q000503:physiopathology*; D018780:Body Surface Potential Mapping; D022062:Electrophysiologic Techniques, Cardiac; D006801:Humans; D008839:Microelectrodes; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000175:diagnosis* / Q000503:physiopathology*