title: Cluster of neonatal infections in Jerusalem due to unusual biochemical variant of Enterobacter sakazakii.
abstract: Reported here is a cluster of infections due to a nitrate-negative variant of Enterobacter sakazakii, which occurred among premature neonates at the Hadassah Hospital, Mount Scopus, Jerusalem, in December 1999-January 2000. Pulsed-field gel electrophoresis showed cluster isolates to be identical but unrelated to previous systemic isolates recovered in 1993 and 1998. The organism was not isolated from infant formula powder, but it was recovered from prepared formula and from a kitchen blender. Elimination of the environmental focus, a change to factory-prepared infant formula, and isolation of affected infants terminated the event. Faecal carriage of Enterobacter sakazakii was observed for up to 18 weeks, emphasising the potential for cross-infection.
authors.affiliation: Department of Clinical Microbiology and Infectious Diseases, Hadassah University Hospital, PO Box 12000, Jerusalem 91120, Israel. block@md.huji.ac.il
authors.forename: C
authors.initials: C
authors.lastname: Block
authors.forename: O
authors.initials: O
authors.lastname: Peleg
authors.forename: N
authors.initials: N
authors.lastname: Minster
authors.forename: B
authors.initials: B
authors.lastname: Bar-Oz
authors.forename: A
authors.initials: A
authors.lastname: Simhon
authors.forename: I
authors.initials: I
authors.lastname: Arad
authors.forename: M
authors.initials: M
authors.lastname: Shapiro
mesh_terms: D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial; D004754:Enterobacter / Q000235:genetics* / Q000472:pathogenicity*; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D014644:Genetic Variation / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology / Q000382:microbiology*; D007557:Israel / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D010641:Phenotype