Henoch-Schönlein nephritis complicated with pulmonary hemorrhage but treated successfully.
Henoch-Schönlein purpura (HSP) is a common vasculitic syndrome in children who, in most cases, achieve complete recovery. Occasionally, however, patients develop nephritis or nephrotic syndrome with renal failure, or develop significant gastrointestinal bleeding. Pulmonary hemorrhage, found mostly in adolescents and adults, and with a high mortality rate, has been reported only in a few prepubertal children, with a slightly better outcome. A 9-year-old-girl with HSP, renal failure, and nephrotic syndrome developed severe bilateral pulmonary hemorrhage. After an unsuccessful trial of glucocorticoid therapy, she showed an excellent response to cytotoxic therapy.
Al-Harbi
Nafaa N
NN
King Faisal Specialist Hospital and Research Center, P.O. Box 40047, Jeddah 21499, Kingdom of Saudi Arabia. nalharby@yahoo.com
D002648:Child; D005260:Female; D006470:Hemorrhage / Q000209:etiology* / Q000628:therapy; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications*; D008171:Lung Diseases / Q000209:etiology* / Q000628:therapy; D009404:Nephrotic Syndrome / Q000150:complications*; D051437:Renal Insufficiency / Q000150:complications*