title: [Molecular basis for the development of type 2 diabetes mellitus].
authors.affiliation: Division of Diabetes, Digestive and Kidney Diseases, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine.
authors.forename: Masato
authors.initials: M
authors.lastname: Kasuga
mesh_terms: D064413:3-Phosphoinositide-Dependent Protein Kinases; D000091162:AMP-Activated Protein Kinase Kinases; D000818:Animals; D017209:Apoptosis; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology*; D004721:Endoplasmic Reticulum / Q000502:physiology; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D007333:Insulin Resistance; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000502:physiology; D015227:Lipid Peroxidation; D019869:Phosphatidylinositol 3-Kinases / Q000502:physiology; D010750:Phosphoproteins / Q000502:physiology; D011494:Protein Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000502:physiology; D011972:Receptor, Insulin / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology
chemical_list: D064413:3-Phosphoinositide-Dependent Protein Kinases; D000091162:AMP-Activated Protein Kinase Kinases; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D019869:Phosphatidylinositol 3-Kinases; D010750:Phosphoproteins; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; D011972:Receptor, Insulin