title: Three-dimensional spiral MR imaging: Application to renal multiphase contrast-enhanced angiography.
abstract: A fast MR pulse sequence with spiral in-plane readout and conventional 3D partition encoding was developed for multiphase contrast-enhanced magnetic resonance angiography (CE-MRA) of the renal vasculature. Compared to a standard multiphase 3D CE-MRA with FLASH readout, an isotropic in-plane spatial resolution of 1.4 x 1.4 mm(2) over 2.0 x 1.4 mm(2) could be achieved with a temporal resolution of 6 sec. The theoretical gain of spatial resolution by using the spiral pulse sequence and the performance in the presence of turbulent flow was evaluated in phantom measurements. Multiphase 3D CE-MRA of the renal arteries was performed in five healthy volunteers using both techniques. A deblurring technique was used to correct the spiral raw data. Thereby, the off-resonance frequencies were determined by minimizing the imaginary part of the data in image space. The chosen correction algorithm was able to reduce image blurring substantially in all MRA phases. The image quality of the spiral CE-MRA pulse sequence was comparable to that of the FLASH CE-MRA with increased spatial resolution and a 25% reduced contrast-to-noise ratio. Additionally, artifacts specific to spiral MRI could be observed which had no impact on the assessment of the renal arteries.
authors.affiliation: Deutsches Krebsforschungszentrum (DKFZ), Abteilung Biophysik und Medizinische Strahlenphysik, Heidelberg, Germany. m.amann@dkfz.de
authors.forename: Michael
authors.initials: M
authors.lastname: Amann
authors.forename: Michael
authors.initials: M
authors.lastname: Bock
authors.forename: Frank
authors.initials: F
authors.lastname: Floemer
authors.forename: Stefan O
authors.initials: SO
authors.lastname: Schoenberg
authors.forename: Lothar R
authors.initials: LR
authors.lastname: Schad
mesh_terms: D000328:Adult; D016477:Artifacts; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007668:Kidney / Q000098:blood supply*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D019047:Phantoms, Imaging; D012077:Renal Artery / Q000033:anatomy & histology
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA