The first zinc-promoted, environmentally friendly, and highly efficient acetoxyallylation of aldehydes in aqueous ammonium chloride.
An exceptionally mild acetoxyallylation of aldehydes in water promoted by zinc is reported, using 3-bromo-1-acetoxyprop-1-ene as starting material; simple diastereoselectivity mainly depends on the nature of the aldehyde.
Lombardo
M
M
Dipartimento di Chimica G. Ciamician, University of Bologna, Bologna, Italy.
Girotti
R
R
Morganti
S
S
Trombini
C
C
D000447:Aldehydes / Q000737:chemistry*; D000643:Ammonium Chloride / Q000737:chemistry; D004787:Environmental Pollution / Q000517:prevention & control*; D009930:Organic Chemicals / Q000138:chemical synthesis*; D012996:Solutions; D014867:Water / Q000737:chemistry; D015032:Zinc / Q000737:chemistry
D000447:Aldehydes; D009930:Organic Chemicals; D012996:Solutions; D000643:Ammonium Chloride; D014867:Water; D015032:Zinc