title: Ruthenium(II) porphyrin catalyzed tandem carbonyl ylide formation and 1,3-dipolar cycloaddition reactions of alpha-diazo ketones.
abstract: [reaction: see text] The ruthenium porphyrin-catalyzed reactions of diazo ketones with pi-unsaturated compounds via carbonyl ylide formation/cycloaddition cascade exhibit product yields and selectivities comparable to the analogous reactions with dirhodium carboxylates as catalysts. By grafting a ruthenium porphyrin on poly(ethylene glycol) (Zhang, J.-L.; Che, C.-M. Org. Lett. 2002, 4, 1911), a recyclable catalytic system is developed with over 5700 product turnovers attained for the reaction of 1-diazo-2,5-hexanedione with dimethyl acetylenedicarboxylate.
authors.affiliation: Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong.
authors.forename: Cong-Ying
authors.initials: CY
authors.lastname: Zhou
authors.forename: Wing-Yiu
authors.initials: WY
authors.lastname: Yu
authors.forename: Chi-Ming
authors.initials: CM
authors.lastname: Che