title: Contribution of research in basic and clinical sciences in Japan.
abstract: OBJECTIVE
  To investigate the degree of Japan's contribution in basic and clinical research in the last decade.
  
  
  METHODS
  Original articles published in 1990-2000 in highly reputed basic and clinical journals were accessed through MEDLINE database. The number of articles having affiliation with a Japanese institution was counted separately for basic and clinical journals.
  
  
  RESULTS
  Of total articles, Japan's contributions in basic and clinical research were 3.1% and 0.7%, respectively (p=0.0001). The recent increase in the contribution was significant for basic research (p=0.01), but not for clinical research (p=0.91).
  
  
  CONCLUSIONS
  The barriers to boosting high quality clinical research in Japan should be determined and accordingly appropriate measures should be taken forthwith.
authors.affiliation: Department of General Medicine and Clinical Epidemiology, Kyoto University Graduate School of Medicine.
authors.forename: Tsuguya
authors.initials: T
authors.lastname: Fukui
authors.forename: Mahbubur
authors.initials: M
authors.lastname: Rahman
mesh_terms: D035843:Biomedical Research; D007564:Japan; D016239:MEDLINE; D011643:Publishing / Q000706:statistics & numerical data