Normocalcemic primary hyperparathyroidism with fractures.
Normocalcemic primary hyperparathyroidism is an uncommon condition usually found among patients with urinary stones. To the best of our knowledge, this is the first case of a patient with normocalcemic primary hyperparathyroidism presenting with bilateral femoral neck fracture. A 45-year-old man had pain both hip joints and limping in for several months. Vertical fractures of bilateral femoral necks were found by radiographs. Laboratory findings showed a normal value of total serum calcium but elevated serum ionized calcium. Serum parathyroid hormone and alkaline phosphatase levels were elevated. The patient was treated with subtrochanteric valgus osteotomy fixed with a dynamic hip screw and total parathyroidectomy. Histopathologic examination showed hyperplasia of the parathyroid glands. At 1-year follow-up, the patient was doing well clinically.
Wu
Po-Hui
PH
Department of Orthopedic Surgery, Chang Gung Memorial Hospital, Kaohsiung, Taiwan. w62102@ms8.hinet.net
Wang
Ching-Jen
CJ
D000469:Alkaline Phosphatase / Q000097:blood; D002118:Calcium / Q000097:blood; D002968:Clavicle / Q000293:injuries; D005265:Femoral Neck Fractures / Q000097:blood / Q000209:etiology* / Q000601:surgery; D005269:Femur / Q000601:surgery; D050723:Fractures, Bone / Q000209:etiology; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000150:complications* / Q000601:surgery; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000097:blood / Q000209:etiology*; D010027:Osteotomy; D010280:Parathyroid Glands / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood; D016105:Parathyroidectomy; D012253:Rib Fractures / Q000209:etiology
D010281:Parathyroid Hormone; D000469:Alkaline Phosphatase; D002118:Calcium