Bidentate carbenoid ester coordination in ruthenium(II) Schiff-base complexes leading to excellent levels of diastereo- and enantioselectivity in catalytic alkene cyclopropanation.
Exceptionally high stereoselectivity (ee < or = 98%, dr < or = 99:1) in the cyclopropanation of alkenes with ethyl diazoacetate using a non-planar ruthenium(II) Schiff-base precatalyst is a result of eta 2C,O binding of the carbenoid ester intermediate, according to DFT calculations.
Munslow
I J
IJ
Department of Chemistry, University of Warwick, Coventry, UK CV4 7AL.
Gillespie
K M
KM
Deeth
R J
RJ
Scott
P
P