title: A photochemical route for efficient cyclopeptide formation with a minimum of protection and activation chemistry.
abstract: An elaborated protocol is described which allows the efficient transformation of di-, tri-, and tetrapeptides into cyclopeptides with a minimum of protection and activation chemistry using the photoinduced electron transfer initiated decarboxylation of N-phthaloyl peptides resulting in C-C coupling between the initially formed carbon radicals.
authors.affiliation: Institute of Organic Chemistry, University of Cologne, Greinstrasse 4, D-50939 Köln, Germany. griesbeck@unikoeln.de
authors.forename: Axel G
authors.initials: AG
authors.lastname: Griesbeck
authors.forename: Thomas
authors.initials: T
authors.lastname: Heinrich
authors.forename: Michael
authors.initials: M
authors.lastname: Oelgemöller
authors.forename: Johann
authors.initials: J
authors.lastname: Lex
authors.forename: Arne
authors.initials: A
authors.lastname: Molis
mesh_terms: D003500:Cyclization; D008958:Models, Molecular; D009842:Oligopeptides / Q000737:chemistry*; D010456:Peptides, Cyclic / Q000138:chemical synthesis*; D010777:Photochemistry
chemical_list: D009842:Oligopeptides; D010456:Peptides, Cyclic