title: Recurrent bronchiolitis obliterans organizing pneumonia in a patient with limited cutaneous systemic sclerosis.
abstract: Systemic sclerosis (SSc) is a generalized disorder characterized by fibrosis and vascular obliteration in the skin, lung, gastrointestinal tract, and kidney. One of its two subsets is a stable, limited cutaneous group (lSSc). Pulmonary involvement in scleroderma is common, and several types of pulmonary disorders are associated with SSc. Bronchiolitis obliterans organizing pneumonia (BOOP) is a rare finding in lung disorders associated with SSc. We describe a case of lSSc with BOOP that was responsive to steroid therapy. Of interest is that the lung disorders appeared in different periods and areas. It might be important to diagnose abnormal shadows in lung fields before treatment of patients with SSc.
authors.affiliation: Department of Internal Medicine, Nanokaichi Municipal Hospital, 643 Nanokaichi, Tomioka, Gunma 370-2343, Japan. yshimizu@med.gunma-u.ac.jp
authors.forename: Yuji
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Hideo
authors.initials: H
authors.lastname: Tsukagoshi
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Nemoto
authors.forename: Manabu
authors.initials: M
authors.lastname: Honma
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Nojima
authors.forename: Masatomo
authors.initials: M
authors.lastname: Mori
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D018549:Cryptogenic Organizing Pneumonia / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D011239:Prednisolone / Q000008:administration & dosage; D013902:Radiography, Thoracic; D012008:Recurrence; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis; D012720:Severity of Illness Index; D013906:Thoracoscopy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D011239:Prednisolone