title: Peeling process in living cell movement under shear flow.
abstract: We present a direct optical observation of the behavior of the contact area between a living cell (Dictyostelium discoideum) and a solid substrate under shear flow. It is shown that the membrane is peeled off the substrate. The relationship between the peeling velocity and the applied force is obtained experimentally and explained from the behavior of individual adhesion bridges. The dissipation occurring during the peeling process is explicitly calculated in terms of out-of-equilibrium thermodynamics.
authors.affiliation: CEA/Grenoble, DRFMC/SI3M, 17 rue des Martyrs, 38054 Grenoble cedex 9, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Décavé
authors.forename: Daniel
authors.initials: D
authors.lastname: Garrivier
authors.forename: Yves
authors.initials: Y
authors.lastname: Bréchet
authors.forename: Franz
authors.initials: F
authors.lastname: Bruckert
authors.forename: Bertrand
authors.initials: B
authors.lastname: Fourcade
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000502:physiology; D002465:Cell Movement / Q000502:physiology*; D004023:Dictyostelium / Q000166:cytology*; D008954:Models, Biological; D013499:Surface Properties