title: Is early osteodistraction a solution for the ascending ramus compartment in hemifacial microsomia? A literature study.
abstract: OBJECTIVE
  In hemifacial microsomia, osteodistraction before skeletal maturation claims to induce both bone- and soft-tissue generation in such a way that conventional bone grafting and soft-tissue grafts are not necessary. Early osteodistraction in facial microsomia would have a positive effect on the 'functional matrix', and allow symmetrical vertical and sagittal expansion of the midface and mandible. The aim of this literature survey was to find evidence for this hypothesis by analysing long-term follow-up reports on distraction histiogenesis in the ascending ramus.
  
  
  METHODS
  Only eight published studies were found, of which only two had more than ten patients, two were case reports, and three were from the same institution.
  
  
  RESULTS
  Invariably, the results pointed towards over-correction, repeated osteodistraction procedures, soft-tissue stretching (but no lateral augmentation), and to soft-tissue complications. The studies did not allow a conclusion to be made as whether increased vertical gain in the ascending ramus was unstable because of decreased growth on the affected side, inborn or iatrogenic, or due to resorption of the bone generated by distraction. To date, there is no evidence that osteodistraction produces better results and has lower morbidity than conventional growth centre transplantation and separate soft-tissue augmentation.
  
  
  CONCLUSIONS
  Recommendations for prospective studies are: sharp differentiation between the four Pruzansky-Kaban mandibular types, multi-centre study of a surgical protocol to increase the sample number using a standard three-dimensional evaluation protocol, and differentiation between decreased growth and collapse of the newly generated bone.
authors.affiliation: Division of Maxillo-Facial Surgery, General Hospital St. Jan, Bruges, Belgium. maurice.mommaerts@azbrugge.be
authors.forename: Maurice Y
authors.initials: MY
authors.lastname: Mommaerts
authors.forename: Krisztián
authors.initials: K
authors.lastname: Nagy
mesh_terms: D000367:Age Factors; D005146:Facial Asymmetry / Q000601:surgery*; D006801:Humans; D008334:Mandible / Q000002:abnormalities / Q000254:growth & development / Q000601:surgery*; D008865:Microstomia / Q000601:surgery; D019647:Oral Surgical Procedures / Q000379:methods*; D019857:Osteogenesis, Distraction; D012008:Recurrence; D016896:Treatment Outcome