Central precocious puberty in girls with Williams syndrome.
We report an estimated prevalence of precocious puberty of 1 in 5 to 6 girls with Williams syndrome (18.3%). Mean menarcheal age of 86 girls with Williams syndrome was 11.5 +/- 1.7 (+/-SD) years. Distribution of menarcheal age was significantly different from that in normal girls (12.9 +/- 1.1 years; n = 759).
Partsch
Carl-Joachim
CJ
University Hospital Kiel, Christian-Albrechts-Universität zu Kiel, Germany.
Japing
Insa
I
Siebert
Reiner
R
Gosch
Angela
A
Wessel
Armin
A
Sippell
Wolfgang G
WG
Pankau
Rainer
R
D000293:Adolescent; D017677:Age Distribution; D016022:Case-Control Studies; D002648:Child; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015995:Prevalence; D011629:Puberty, Precocious / Q000453:epidemiology / Q000209:etiology*; D018709:Statistics, Nonparametric; D018980:Williams Syndrome / Q000150:complications*