[Rapid manufacturing of degradable porous polymer bone scaffold].
Making bone scaffold through tissue engineering method presents a new choice for both the patients and the doctors of orthopaedics. The biodegradable polymer PLA is chosen to make porous fundus scaffold jetting through special designed nozzle on multi-functional rapid prototyping machine controlled by computer according to the CT data CAD model. The scaffold is then chemically aggregated to compound with collagen-hydroxyapatite, and the ideal bone repair material is obtained. Animal experiment has indicated the correctness of this conclusion.
Shi
Tingchun
T
Laser Rapid Prototyping Center, Tsinghua University, Beijing 100084.
Yue
Xiuyan
X
Xiong
Zhuo
Z
Zhang
Renji
R
Yan
Yongnian
Y
D020341:Absorbable Implants; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D001842:Bone and Bones; D003094:Collagen / Q000737:chemistry; D017886:Durapatite / Q000737:chemistry; D006801:Humans; D019344:Lactic Acid / Q000138:chemical synthesis; D011091:Polyesters; D011108:Polymers / Q000138:chemical synthesis; D016062:Porosity; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry*
D001672:Biocompatible Materials; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide); D003094:Collagen; D017886:Durapatite