Prominent matched hypoperfusion in an intact cerebellum after a solitary middle cerebellar peduncle infarct.
We examined the cerebellar metabolism of a 61-year-old man with a small infarct in the left middle cerebellar peduncle and an intact cerebellum. Positron emission tomographic images obtained 28 days after onset showed prominent hypoperfusion and hypometabolism (almost 50% below the normal level) in the left cerebellar hemisphere. This case report shows that neural deafferentation may cause prominent hypometabolism without morphologic changes in the cerebellum. An arrest in synaptic activity may be the most important factor for the adaptive decrease in oxygen metabolism seen in ischemic brain.
Takasawa
Masashi
M
Department of Neurology and Cerebrovascular Disease, Osaka University Hospital, Japan.
Kitagawa
Kazuo
K
Ohtsuki
Toshiho
T
Oku
Naohiko
N
Hashikawa
Kazuo
K
Sakoda
Saburo
S
Hori
Masatsugu
M
Matsumoto
Masayasu
M
D020520:Brain Infarction / Q000175:diagnosis / Q000378:metabolism*; D002531:Cerebellum / Q000098:blood supply* / Q000378:metabolism; D002540:Cerebral Cortex / Q000098:blood supply / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D014055:Tomography, Emission-Computed
D010100:Oxygen