title: Monolithic silica columns for high-efficiency chromatographic separations.
abstract: Studies on the structural and chromatographic properties of monolithic silica columns were reviewed. Monolithic silica columns prepared from tetraalkoxysilane by a sol-gel method showed high efficiency and high permeability on the basis of the small-sized silica skeletons, large-sized through-pores, and resulting through-pore size/skeleton size ratios much larger than those found in a particle-packed column.
authors.affiliation: Department of Polymer Science and Engineering, Kyoto Institute of Technology, Japan. nobuo@ipc.kit.ac.jp
authors.forename: Nobuo
authors.initials: N
authors.lastname: Tanak
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Norio
authors.initials: N
authors.lastname: Ishizuka
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Minakuchi
authors.forename: Kazuki
authors.initials: K
authors.lastname: Nakanishi
authors.forename: Ken
authors.initials: K
authors.lastname: Hosoya
authors.forename: Tohru
authors.initials: T
authors.lastname: Ikegami
mesh_terms: D002853:Chromatography, Liquid / Q000295:instrumentation*; D008855:Microscopy, Electron, Scanning; D012822:Silicon Dioxide
chemical_list: D012822:Silicon Dioxide