Free radical scavengers from the heartwood of Juniperus chinensis.
The antioxidant activity of Juniperus chinensis (Cupressaceae) was determined by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl). The methanolic extract of J. chinensis heartwood showed the strong antioxidant activity. The antioxidant activity of n-BuOH soluble fraction was stronger than that of the others, and the fraction was subjected to purification by repeated silica gel and Sephadex LH-20 column chromatography. Quercetin, naringenin, taxifolin, aromadendrin and isoquercitrin were isolated from the n-BuOH fraction. Their structures were elucidated by physico-chemical and spectroscopic studies.
Lim
Jong Pil
JP
College of Pharmacy, Woosuk University, Samrye, Korea.
Song
Young Cheol
YC
Kim
Jin Wook
JW
Ku
Chung Hwan
CH
Eun
Jae Soon
JS
Leem
Kang Hyun
KH
Kim
Dae Keun
DK
D001713:Biphenyl Compounds; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D016166:Free Radical Scavengers / Q000302:isolation & purification* / Q000494:pharmacology*; D007202:Indicators and Reagents; D018653:Juniperus / Q000737:chemistry*; D007723:Korea; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014934:Wood
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl