Catalytic C-F activation of polyfluorinated pyridines by nickel-mediated cross-coupling reactions.
The cross-coupling reaction of pentafluoropyridine with tributyl(vinyl)tin affording 2-vinyltetrafluoropyridine by activation of a carbon-fluorine bond is catalysed by [NiF(2-C5NF4)(PEt3)2]; a similar reaction is observed with 2,3,5,6-tetrafluoropyridine.
Braun
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Fakultät für Chemie, Universität Bielefeld, Postfach 100131, 33501 Bielefeld, Germany. thomas.braun@uni-bielefeld.de
Perutz
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Sladek
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MI