title: [Short-term therapeutic fasting in the treatment of chronic pain and fatigue syndromes--well-being and side effects with and without mineral supplements].
abstract: BACKGROUND
  Fasting followed by vegetarian diet has shown to be an effective treatment for rheumatoid arthritis, moreover fasting is frequently used as an adjunctive treatment in chronic pain and stress/exhaustion syndromes. Data on well-being and the frequency of side effects during fasting are mostly retrospective. Mineral supplements are frequently used in order to compensate for fasting-induced tissue acidosis and to reduce side effects. There are only limited data that support this practice.
  
  
  OBJECTIVE
  To study the effects of oral mineral supplements on common side effects and well-being during short-term fasting.
  
  
  METHODS
  209 consecutive inpatients with chronic pain/exhaustion syndromes were recruited. In a controlled non-randomised study design all patients underwent fasting (250 kcal; 3 l fluid intake/day) over 7 days, in study phase 1 without (n = 103) and in study phase 2 with (n = 106) concomitant prescription of standardised oral mineral supplements (3 x 2 to 3 x 3 Bullrich's Vital). Weight, blood pressure and urinary pH were recorded daily. Well-being and mood as well as common side effects (i.e. fatigue, hunger, heart burn, headache) were assessed with standardised self-reports.
  
  
  RESULTS
  Baseline characteristics of the 209 patients (mean age 54.7 +/- 10.5 years; 83.3% female) were balanced. Both groups showed a fasting-induced decrease of blood pressure, a slight decrease in mood and well-being on days 3 and 4 with consecutive increase and moderate hunger, i.e. in the evening. Side effects and general tolerability of fasting as well as well-being and mood were not different between the groups. There were no serious side effects in both groups.
  
  
  CONCLUSIONS
  Short-term fasting in inpatients with pain and stress syndromes is safe and well tolerated, concomitant mineral supplements have no additive benefit.
authors.affiliation: Abteilung für Innere Medizin V, Naturheilkunde und Integrative Medizin, Kliniken Essen Mitte, Essen.
authors.forename: A
authors.initials: A
authors.lastname: Michalsen
authors.forename: W
authors.initials: W
authors.lastname: Weidenhammer
authors.forename: D
authors.initials: D
authors.lastname: Melchart
authors.forename: J
authors.initials: J
authors.lastname: Langhorst
authors.forename: J
authors.initials: J
authors.lastname: Saha
authors.forename: G
authors.initials: G
authors.lastname: Dobos
mesh_terms: D002908:Chronic Disease; D019587:Dietary Supplements; D005215:Fasting / Q000009:adverse effects / Q000502:physiology; D015673:Fatigue Syndrome, Chronic / Q000178:diet therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000008:administration & dosage*; D010146:Pain / Q000178:diet therapy*; D013577:Syndrome
chemical_list: D008903:Minerals