Strategies for dielectrophoretic separation in laboratory-on-a-chip systems.
Dielectrophoresis--the induced motion of polarizable particles in nonuniform fields--has proven to be an effective method for the separation of bioparticles such as cells, viruses and proteins. In this paper, the application of dielectrophoresis in miniaturized laboratories-on-a-chip is discussed, and strategies are described for using dielectrophoresis both for the binary separation of bioparticles and for the fractionation of many populations in such devices.
Hughes
Michael P
MP
Centre for Biomedical Engineering, School of Engineering, University of Surrey, Guildford, Surrey GU2 7XH, United Kingdom. m.hughes@surrey.ac.uk
D002469:Cell Separation / Q000295:instrumentation / Q000379:methods; D004583:Electrons; D019075:Electrophoresis, Capillary / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D007477:Ions; D046911:Macromolecular Substances; D008904:Miniaturization / Q000295:instrumentation; D036103:Nanotechnology / Q000295:instrumentation; D012212:Rheology
D007477:Ions; D046911:Macromolecular Substances