title: Antiretroviral drug resistance mutations in antiretroviral-naive prisoners.
abstract: We assessed the incidence of antiretroviral drug resistance in a cohort of 25 antiretroviral-naive, human immunodeficiency virus-positive inmates in Massachusetts. Silent mutations, unexpected mutations at resistant sites, and resistance mutations were recorded. Among these inmates, we found a prevalence of drug resistance mutations that was equivalent to the prevalence previously found in nonprison populations in the same state.
authors.affiliation: Infectious Disease Section, Lemuel Shattuck Hospital and Tufts University School of Medicine, Jamaica Plain, MA 02130 , USA. dstone@lifespan.org
authors.forename: David R
authors.initials: DR
authors.lastname: Stone
authors.forename: Colleen
authors.initials: C
authors.lastname: Corcoran
authors.forename: Alysse
authors.initials: A
authors.lastname: Wurcel
authors.forename: Barbara
authors.initials: B
authors.lastname: McGovern
authors.forename: James
authors.initials: J
authors.lastname: Quirk
authors.forename: Arthur
authors.initials: A
authors.lastname: Brewer
authors.forename: Lorraine
authors.initials: L
authors.lastname: Sutton
authors.forename: Richard T
authors.initials: RT
authors.lastname: D'Aquila
mesh_terms: D019380:Anti-HIV Agents / Q000494:pharmacology*; D015331:Cohort Studies; D004352:Drug Resistance, Microbial / Q000235:genetics*; D005787:Gene Frequency; D005838:Genotype; D006678:HIV / Q000187:drug effects / Q000235:genetics*; D015658:HIV Infections / Q000188:drug therapy / Q000821:virology; D006801:Humans; D015994:Incidence; D008404:Massachusetts / Q000453:epidemiology; D009154:Mutation; D011329:Prisoners
chemical_list: D019380:Anti-HIV Agents