[DHEA and rejuvenating intracrinology? Between reason and magic].
Slowing down ageing is a goal for a large part of the population. Some mercantile claims hold out bright prospects to DHEA. The effects of this hormone manifest themselves after intracrine conversion. In the skin, sebaceous glands enlarge and seborrhoea increases in post-menopausal women. No other effect is clinically discernable on the skin. At this level, DHEA does not show efficacy comparable to that of other anti-ageing compounds.
Bourguignon
R
R
Service, Université de Liège, Service de Dermatopathologie.
Uhoda
I
I
Henry
F
F
Piérard-Franchimont
C
C
Piérard
G E
GE
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000368:Aged; D000375:Aging / Q000187:drug effects*; D003687:Dehydroepiandrosterone / Q000494:pharmacology*; D012628:Dermatitis, Seborrheic / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause; D012627:Sebaceous Glands / Q000187:drug effects / Q000473:pathology
D000276:Adjuvants, Immunologic; D003687:Dehydroepiandrosterone