Novel spermine-based cationic gemini surfactants for gene delivery.
Two types of spermine-based gemini surfactants have been synthesised; structure-activity studies have shown one type to be far superior in gene transection than the other.
Ronsin
G
G
University Chemical Laboratory, Lensfield Road, Cambridge, UK CB1 1EW.
Perrin
C
C
Guédat
P
P
Kremer
A
A
Camilleri
P
P
Kirby
A J
AJ
D002460:Cell Line; D004247:DNA / Q000235:genetics; D018014:Gene Transfer Techniques; D013096:Spermine / Q000031:analogs & derivatives* / Q000737:chemistry*; D013329:Structure-Activity Relationship; D013501:Surface-Active Agents / Q000737:chemistry*; D014162:Transfection
D013501:Surface-Active Agents; D013096:Spermine; D004247:DNA