Living-unrelated renal transplantation at the University of Wisconsin.
Since 1984, we have performed 243 living-unrelated renal transplants at the University of Wisconsin. Rejection occurred in 47% of the patients. Graft loss occurred in 59 patients and 39 patients died. Graft survival in LURD transplants at 10 years is 54% and 43% at 15 years. Patient survival is 68% at 10 years and 54% at 15 years. These long-term results demonstrate that LURD is equivalent to haploidentical renal transplantation and superior to cadaveric transplantation. Husband-to-wife donation demonstrated improved graft survival when compared with wife-to-husband and nonspousal donation. Living-unrelated renal transplantation has been utilized successfully at the University of Wisconsin and may help to alleviate the donor shortage.
Shames
B D
BD
Division of Transplantation, Department of Surgery, University of Wisconsin, Madison, USA.
D'Alessandro
A M
AM
Pirsch
J D
JD
Knechtle
S J
SJ
Odorico
J S
JS
Becker
Y T
YT
Kalayoglu
M
M
Chin
L T
LT
Sollinger
H W
HW
D000046:Academic Medical Centers; D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D002102:Cadaver; D002648:Child; D005260:Female; D006084:Graft Rejection / Q000453:epidemiology; D006085:Graft Survival; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous; D014922:Wisconsin