What evidence would prove the amyloid hypothesis? Towards rational drug treatments for Alzheimer's disease.
Morgan
Dave
D
Department of Pharmacology and Biochemistry, University of South Florida College of Medicine, Tampa FL 33612-4799, USA. dmorgan@hsc.usf.edu
Keller
R Kennedy
RK
D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D016229:Amyloid beta-Peptides / Q000378:metabolism; D001057:Apolipoproteins E / Q000378:metabolism; D001921:Brain / Q000473:pathology; D002791:Cholesterol, Dietary / Q000009:adverse effects; D004195:Disease Models, Animal; D006801:Humans; D016874:Neurofibrillary Tangles / Q000473:pathology; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D012307:Risk Factors
D016229:Amyloid beta-Peptides; D001057:Apolipoproteins E; D002791:Cholesterol, Dietary; D018696:Neuroprotective Agents