title: Necrotizing fasciitis following liver and small intestine transplantation.
abstract: Necrotizing fasciitis is a rare, subcutaneous infection. It can occur in patients after solid-organ transplantation. We herein report two patients who developed necrotizing fasciitis following combined liver and small intestine transplantation. The first patient experienced this infection 4 yr after transplantation and 1 yr after the closure of the ileostomy. The second patient suffered from necrotizing fasciitis 2 days after the transplant. Both cases were diagnosed on the physical findings, culture of subcutaneous lavage, and the computed tomography findings. The site of entrance of the organism was not clear in either case. Both patients had a fulminant course and died within 1 week from the onset, despite aggressive surgical intervention. Therefore, necrotizing fasciitis has to be recognized as a potential complication of intestinal transplantation.
authors.affiliation: Division of Transplantation, University of Miami School of Medicine, Miami, Florida, USA.
authors.forename: Shogo
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Kato
authors.forename: Seigo
authors.initials: S
authors.lastname: Nishida
authors.forename: Efren
authors.initials: E
authors.lastname: Buttrago
authors.forename: Greggorio
authors.initials: G
authors.lastname: Maldini
authors.forename: Naveen
authors.initials: N
authors.lastname: Mittal
authors.forename: John
authors.initials: J
authors.lastname: Thompson
authors.forename: Andreas G
authors.initials: AG
authors.lastname: Tzakis
mesh_terms: D002675:Child, Preschool; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000209:etiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D007421:Intestine, Small / Q000637:transplantation*; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male