title: Occupation, exposure to chemicals and risk of gliomas and meningiomas in Sweden.
abstract: BACKGROUND
  Occupational exposures may be related to the development of brain cancer. The objective was to estimate occupational-specific risk of gliomas and meningiomas among Swedish men and women gainfully employed in 1970 over the period 1971-1989, and the influence of occupational exposure to chemical substances.
  
  
  METHODS
  A dataset linking cancer diagnoses from the Swedish national cancer register to occupational and demographical data obtained in the 1970 census was used to fit log-linear Poisson models, in order to obtain relative risks adjusted by age, period, geographical area and town size. Exposure to 13 chemicals was assessed using a Swedish job-exposure matrix.
  
  
  RESULTS
  The main findings of this study among men were the increased risk of glioma with occupational exposure to arsenic, mercury, and petroleum products and of meningioma with lead. Women in occupational sectors with a higher socio-economic status showed an increased incidence of both, gliomas and meningiomas.
  
  
  CONCLUSIONS
  Occupational exposure to some chemicals appeared to be related with an increased risk of glioma and meningioma in men. Exposures involved in glioma and meningioma development seemed to be different.
authors.affiliation: Cancer and Environmental Epidemiology Area, National Center for Epidemiology, Carlos III Institute of Health, Madrid, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Navas-Acién
authors.forename: Marina
authors.initials: M
authors.lastname: Pollán
authors.forename: Per
authors.initials: P
authors.lastname: Gustavsson
authors.forename: Nils
authors.initials: N
authors.lastname: Plato
mesh_terms: D000328:Adult; D017677:Age Distribution; D001932:Brain Neoplasms / Q000453:epidemiology* / Q000209:etiology; D015331:Cohort Studies; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D005260:Female; D005910:Glioma / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007287:Inorganic Chemicals / Q000009:adverse effects* / Q000032:analysis; D008297:Male; D008579:Meningioma / Q000453:epidemiology* / Q000209:etiology; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis; D016272:Occupational Health; D009790:Occupations; D016012:Poisson Distribution; D012042:Registries; D018570:Risk Assessment; D012307:Risk Factors; D017678:Sex Distribution; D016019:Survival Analysis; D013548:Sweden / Q000453:epidemiology
chemical_list: D007287:Inorganic Chemicals