Solubility of hypericin in methanol and methanol-pyridine.
The solubility of hypericin in methanol and methanol-pyridine (99:1, v/v) was determined. The addition of pyridine turned out to enhance the solubility of hypericin. In pure methanol only 37.17 micrograms/ml could be dissolved. In comparison, 320.91 micrograms hypericin were soluble in one ml methanol-pyridine (99:1, v/v).
Wirz
A
A
Department of Applied BioSciences, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland.
Meier
B
B
Sticher
O
O
D000873:Anthracenes; D000928:Antidepressive Agents / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D000432:Methanol / Q000737:chemistry; D010569:Perylene / Q000031:analogs & derivatives* / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D012015:Reference Standards; D012995:Solubility; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet
D000873:Anthracenes; D000928:Antidepressive Agents; D011725:Pyridines; D012997:Solvents; D010569:Perylene; C004965:hypericin; C023666:pyridine; D000432:Methanol