title: Successful treatment of fulminant pneumococcal sepsis with recombinant tissue plasminogen activator.
abstract: This case report describes a patient with a rapidly progressive pneumococcal septic shock and purpura fulminans. Despite maximal conventional treatment, the patient developed progressive multiple organ failure with imminent necrosis of the extremities. This extremely rare, but often fatal, disease responded dramatically to the infusion of recombinant tissue plasminogen activator.
authors.affiliation: Department of Intensive Care Medicine, Jeroen Bosch Ziekenhuis, P.O. Box 90153, 5200 ME, 's-Hertogenbosch, The Netherlands
authors.forename: H
authors.initials: H
authors.lastname: Akol
authors.forename: E
authors.initials: E
authors.lastname: Boon
authors.forename: F
authors.initials: F
authors.lastname: van Haren
authors.forename: J
authors.initials: J
authors.lastname: van der Hoeven