[Relationship between the expression of bcl-2 apoptosis and acute myelogenous leukemia prognosis].
In order to check the anti-apoptosis gene bcl-2 protein expression in 58 AML patients we used the immunohistochemical method, and analyse the relationship between bcl-2 protein and prognosis of AML. The result showed that the high expression of bcl-2 protein was related to poor clinical prognosis of AML. This shows that the expression of bcl-2 gene can serve as an index for the prognosis of AML.
Liu
J
J
Department of Hematology, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Cao
P
P
Qi
Z H
ZH
D000293:Adolescent; D000328:Adult; D014408:Biomarkers, Tumor; D005260:Female; D015870:Gene Expression; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000096:biosynthesis* / Q000235:genetics
D014408:Biomarkers, Tumor; D019253:Proto-Oncogene Proteins c-bcl-2