title: Hyperhomocysteinemia as risk factor for ischemic and hemorrhagic stroke in newborn infants.
abstract: We studied the association between plasma total homocysteine concentrations and the occurrence of stroke in newborn infants (n = 24). Newborn infants with stroke had significantly higher mean total homocysteine concentrations compared with 94 healthy newborn infants (9.3 vs 7.4 micromol/L). The odds ratio for neonatal stroke was 3.95 (95" CI 1.53-10.16) at the 80" cutoff level.
authors.affiliation: Department of Pediatrics, University of Nijmegen Medical Center, Nijmegen, The Netherlands.
authors.forename: Marije
authors.initials: M
authors.lastname: Hogeveen
authors.forename: Henk J
authors.initials: HJ
authors.lastname: Blom
authors.forename: Marjolein
authors.initials: M
authors.lastname: Van Amerongen
authors.forename: Bas
authors.initials: B
authors.lastname: Boogmans
authors.forename: Ingrid M
authors.initials: IM
authors.lastname: Van Beynum
authors.forename: Margot
authors.initials: M
authors.lastname: Van De Bor
mesh_terms: D002545:Brain Ischemia / Q000453:epidemiology / Q000209:etiology*; D002543:Cerebral Hemorrhage / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D020138:Hyperhomocysteinemia / Q000150:complications*; D007231:Infant, Newborn; D016015:Logistic Models; D009426:Netherlands / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology / Q000209:etiology*