Kaposi's sarcoma herpesvirus and HIV-1 seroprevalences in prostitutes in Djibouti.
Kaposi's sarcoma herpesvirus (KSHV) is linked causally to Kaposi's sarcoma. Epidemiological studies have shown that KSHV transmission can occur during sex among homosexual men, but heterosexual transmission seems to be very rare in KSHV low prevalence countries. A seroepidemiological study was conducted to determine whether KSHV is transmitted sexually between heterosexuals in an endemic country. Sera from 282 subjects of African origin living in Djibouti were tested for antibodies to KSHV and HIV-1. Among the 282 individuals, 43 were female prostitutes working in the streets (group 1), 123 were female prostitutes working in luxury bars (group 2), 41 were non-prostitute females (group 3), and 75 were non-prostitute males (group 4). KSHV seroprevalence was 26, 20, 17, and 36% in groups 1, 2, 3, and 4, respectively. The seroprevalence of KSHV is not different between street or bar prostitutes and non-prostitute females (OR = 1.67; P = 0.34 and OR = 1.18; P = 0.73). These results suggest that in this endemic country commercial sex work does not seem to be a risk factor for KSHV infection and provides evidence against heterosexual transmission of KSHV in the female population studied.
Marcelin
Anne-Geneviève
AG
Department of Virology-CERVI, Pitié-Salpêtrière Hospital, Paris, France.
Grandadam
Marc
M
Flandre
Philippe
P
Nicand
Elisabeth
E
Milliancourt
Catherine
C
Koeck
Jean-Louis
JL
Philippon
Michel
M
Teyssou
Remy
R
Agut
Henri
H
Dupin
Nicolas
N
Calvez
Vincent
V
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D015730:Djibouti / Q000453:epidemiology; D005260:Female; D015528:HIV Seroprevalence; D015497:HIV-1; D006566:Herpesviridae Infections / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D019288:Herpesvirus 8, Human / Q000276:immunology*; D020010:Heterosexuality; D006801:Humans; D008297:Male; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D011477:Sex Work
D000914:Antibodies, Viral