title: Sclerosing encapsulating peritonitis: regional changes of peritoneum.
abstract: Sclerosing encapsulating peritonitis (SEP) is characterized by the diffuse appearance of marked sclerotic thickening of the peritoneal membrane. We experienced a case with SEP accompanied by regional changes of peritoneum. A 37-year-old woman with end-stage renal failure was started on continuous ambulatory peritoneal dialysis in 1985 and was transferred to hemodialysis in 1997. She was admitted because of ileus in 1998 with SEP and died of septicemia. The diagnosis of SEP was confirmed via the autopsy. The root of the mesentery was retracted and shortened. Since the peritoneal change was marked in the regions with free margin of mesentery and was less apparent in the regions not adhered to mesentery, it is indicated that mechanical stress also contributes to the occurrence of SEP. Since calcification and ossification were only seen in a free margin of small bowel from mesentery, it is suggested that there is a close relationship between calcification and ossification. Since fibrosis invaded into the muscle layer, dysfunction of bowel movement as well as bowel obstruction contributed to the appearance of ileus. It is suggested that mechanical stress by the root of mesentery which is retracted and shortened also contributes to the appearance of SEP.
authors.affiliation: Second Department of Internal Medicine, Nihon University School of Medicine, Itabashi-ku, Tokyo 173-8610, Japan. kokada@med.nihon-u.ac.jp
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Okada
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Onishi
authors.forename: Toshinori
authors.initials: T
authors.lastname: Oinuma
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nagura
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Soma
authors.forename: Satoshi
authors.initials: S
authors.lastname: Saito
authors.forename: Katsuo
authors.initials: K
authors.lastname: Kanmatsuse
authors.forename: Susumu
authors.initials: S
authors.lastname: Takahashi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010537:Peritoneum / Q000473:pathology; D010538:Peritonitis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology*; D006435:Renal Dialysis; D012598:Sclerosis; D013314:Stress, Mechanical