Regiocontrolled deprotonative-zincation of bromopyridines using aminozincates.
Regiochemistry in the deprotonation of bromopyridines was found to be greatly influenced by the choice of metal amide base, and DA-zincate and TMP-zincate turned out to be excellent complementary practical agents for regioselective metalation of bromopyridines.
Imahori
T
T
Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama, Aoba-ku, Sendai 980-8578, Japan.
Uchiyama
M
M
Sakamoto
T
T
Kondo
Y
Y