Multiple hyperkeratotic spicules and myeloma.
We report the case of a 58-year-old patient with multiple myeloma with a monoclonal gammopathy of the IgG type, who developed a striking eruption characterized by multiple hyperkeratotic spicules of the face, nose and scalp. Light-microscopic studies revealed a follicular orthohyperkeratosis, while direct immunofluorescence microscopy remained negative. Hence, our patient presented features characteristic of a rare distinctive disorder associated with an underlying paraprotein or multiple myeloma, paraneoplastic hyperkeratotic spicules.
Braun
R P
RP
Department of Dermatology, University Hospital, Geneva, Switzerland. braun@cmu.inige.ch
Skaria
A M
AM
Saurat
J-H
JH
Borradori
L
L
D006801:Humans; D007642:Keratosis / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications*; D010257:Paraneoplastic Syndromes / Q000473:pathology; D012867:Skin / Q000473:pathology