Effects of sympathetic denervation on follicular distribution, oestradiol and progesterone serum levels in prepubertal hemi-ovariectomized female guinea pig.
Hemi-gonadectomy performed in prepubertal female guinea pigs is followed by a compensatory ovarian hypertrophy (COH) and compensatory ovulation (CO). Sympathetic denervation diminished the COH (left ovary: 28 +/- 1.6% versus 46 +/- 4% (control), P < 0.05; and right ovary: 21.3 +/- 3.2% versus 34.2 +/- 3.7% (control), P < 0.01) and does not modify the CO. The mean follicular diameter increased only in the right ovary of hemi-gonadectomized animals. This increase is greater in the hemi-gonadectomized-denervated groups. The mean follicular diameter measured in the right and left ovaries showed an opposite response in hemi-ovariectomized and hemi-ovariectomized-denervated animals: the diameter increased in the right ovary without modifications in the left. Present results add further support to the participation of ovarian innervation on the mechanisms, which regulate follicular development.
Riboni
L
L
Escuela de Biología, BUAP, Edificio 76, Ciudad Universitaria, CP 72000, Puebla, Pue, Mexico. Iriboni@siu.buap.mx
D000818:Animals; D004958:Estradiol / Q000097:blood*; D005260:Female; D006168:Guinea Pigs / Q000097:blood / Q000502:physiology* / Q000601:surgery; D006984:Hypertrophy; D006080:Ovarian Follicle / Q000033:anatomy & histology / Q000502:physiology; D010052:Ovariectomy / Q000662:veterinary*; D010053:Ovary / Q000033:anatomy & histology / Q000294:innervation / Q000502:physiology*; D010060:Ovulation / Q000502:physiology; D011374:Progesterone / Q000097:blood*; D013562:Sympathectomy / Q000662:veterinary*
D011374:Progesterone; D004958:Estradiol