title: Successful non-surgical treatment of brain abscess and necrotizing fasciitis caused by Bacillus cereus.
abstract: Musculoskeletal and central nervous system infections caused by Bacillus cereus are very rare. Only a few cases have been reported, whose clinical courses strongly suggested that surgical procedures combined with appropriate antimicrobial therapy are necessary to cure these infections. A 60-year-old man with severe neutropenia due to myelodysplastic syndrome, developing necrotizing fasciitis and brain abscess caused by Bacillus cereus is reported. Without performing any surgical procedures, the patient was successfully treated with systemic antimicrobial therapy combined with granulocyte colony stimulating factor, which contributed to the increase in the neutrophil count.
authors.affiliation: Department of Medicine, Keio University School of Medicine, Tokyo.
authors.forename: Takehiko
authors.initials: T
authors.lastname: Mori
authors.forename: Michihide
authors.initials: M
authors.lastname: Tokuhira
authors.forename: Yujiro
authors.initials: Y
authors.lastname: Takae
authors.forename: Shigehisa
authors.initials: S
authors.lastname: Mori
authors.forename: Hirosi
authors.initials: H
authors.lastname: Suzuki
authors.forename: Toru
authors.initials: T
authors.lastname: Abe
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Takeuchi
mesh_terms: D000900:Anti-Bacterial Agents; D016863:Bacillaceae Infections / Q000150:complications* / Q000188:drug therapy*; D001409:Bacillus cereus / Q000472:pathogenicity; D001922:Brain Abscess / Q000150:complications* / Q000188:drug therapy*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D019115:Fasciitis, Necrotizing / Q000150:complications* / Q000188:drug therapy*; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications; D009503:Neutropenia / Q000150:complications / Q000188:drug therapy; D011994:Recombinant Proteins
chemical_list: D000900:Anti-Bacterial Agents; D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor