[Immunomodulating effects of carbohydrate and lipid metabolism activators in acute cold stress].
Joint injection of the activators of carbohydrate (thiamine, riboxin) and lipid (carnitin, biotin) metabolism in pairs reduces the expression of the decrease of the functional-metabolic activity of blood leukocytes and the inhibition of the immunological reactivity of organism, caused by air and immersion cooling. The most expressed immunomodulative effect is caused by the joint injection of thiamine and biotin.
Avakian
A R
AR
Biochemistry Department, Kursk State Medical University, ul. K. Marksa 3a, Kursk, 305033 Russia.
Lazarev
A I
AI
Prokopenko
L G
LG
Uteshev
B S
BS
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D001710:Biotin / Q000494:pharmacology; D050260:Carbohydrate Metabolism; D002331:Carnitine / Q000494:pharmacology; D003080:Cold Temperature; D004357:Drug Synergism; D004912:Erythrocytes / Q000276:immunology; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007101:Immersion; D007290:Inosine Diphosphate / Q000494:pharmacology; D007963:Leukocytes, Mononuclear / Q000187:drug effects / Q000378:metabolism; D050356:Lipid Metabolism; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000209:etiology / Q000276:immunology* / Q000378:metabolism*; D013831:Thiamine / Q000494:pharmacology
D000276:Adjuvants, Immunologic; D001710:Biotin; D007290:Inosine Diphosphate; D002331:Carnitine; D013831:Thiamine