Bidentate lactate binding in aqueous solution in a cationic, heptadentate lanthanide complex: an effective chiral derivatising agent.
The X-ray crystal structures of cationic, heptadentate lanthanide complexes of holmium and ytterbium bound to lactate are reported and the observed bidentate chelation in the solid state is consistent with near-IR CD (Yb) and solution NMR measurements; the complexes are shown to act as aqueous chiral derivatising agents for alpha-hydroxy acids.
Dickins
R S
RS
Department of Chemistry, University of Durham, South Road, Durham, UK DH1 3LE. R.S.Dickins@durham.ac.uk
Love
C S
CS
Puschmann
H
H
D001665:Binding Sites; D018360:Crystallography, X-Ray; D019344:Lactic Acid / Q000032:analysis* / Q000737:chemistry; D028581:Lanthanoid Series Elements / Q000737:chemistry; D008024:Ligands; D008279:Magnetic Resonance Imaging / Q000379:methods; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D012996:Solutions; D013237:Stereoisomerism
D028581:Lanthanoid Series Elements; D008024:Ligands; D009942:Organometallic Compounds; D012996:Solutions; D019344:Lactic Acid