Unusual reaction of 2-(trifluoromethyl)-1,2-dihydro-3lambda(6)-thieno- [2,3-c]chromen-3,3,4-triones with hydrazine as a new route to 3-hydrazinopyridazine derivatives.
Oxidation of 2-(trifluoromethyl)-1,2-dihydro-4H-thieno[2,3-c]chromen-4-ones 2 with H(2)O(2) in AcOH gives 2-(trifluoromethyl)-1,2-dihydrothieno[2,3-c]chromen-3,3,4-triones 3, which are transformed into 3-hydrazinopyridazine derivatives 4 in high yields by treatment with hydrazine hydrate in ethanol.
Sosnovskikh
Vyacheslav Ya
VY
Department of Chemistry, Ural State University, 620083 Ekaterinburg, Russian Federation. vyacheslav.sosnovskikh@usu.ru
Usachev
Boris I
BI
Vorontsov
Ivan I
II