Antiretroviral drug resistance mutations in antiretroviral-naive prisoners.
We assessed the incidence of antiretroviral drug resistance in a cohort of 25 antiretroviral-naive, human immunodeficiency virus-positive inmates in Massachusetts. Silent mutations, unexpected mutations at resistant sites, and resistance mutations were recorded. Among these inmates, we found a prevalence of drug resistance mutations that was equivalent to the prevalence previously found in nonprison populations in the same state.
Stone
David R
DR
Infectious Disease Section, Lemuel Shattuck Hospital and Tufts University School of Medicine, Jamaica Plain, MA 02130 , USA. dstone@lifespan.org
Corcoran
Colleen
C
Wurcel
Alysse
A
McGovern
Barbara
B
Quirk
James
J
Brewer
Arthur
A
Sutton
Lorraine
L
D'Aquila
Richard T
RT
D019380:Anti-HIV Agents / Q000494:pharmacology*; D015331:Cohort Studies; D004352:Drug Resistance, Microbial / Q000235:genetics*; D005787:Gene Frequency; D005838:Genotype; D006678:HIV / Q000187:drug effects / Q000235:genetics*; D015658:HIV Infections / Q000188:drug therapy / Q000821:virology; D006801:Humans; D015994:Incidence; D008404:Massachusetts / Q000453:epidemiology; D009154:Mutation; D011329:Prisoners
D019380:Anti-HIV Agents