Ruthenium-catalysed asymmetric hydrosilylation of ketoximes using chiral oxazolinylferrocenylphosphines.
Chiral ruthenium(II) complexes, RuCl2(PPh3)(oxazolinylferrocenylphosphine), have been found to be effective catalysts for asymmetric hydrosilylation of ketoximes to give the corresponding primary amines in good yields with high enantioselectivities (up to 89% ee) after acid hydrolysis.
Takei
I
I
Institute of Industrial Science, University of Tokyo, Komaba, Meguro-ku, Tokyo 153-8505, Japan.
Nishibayashi
Y
Y
Ishii
Y
Y
Mizobe
Y
Y
Uemura
S
S
Hidai
M
M
D000588:Amines / Q000138:chemical synthesis*; D002384:Catalysis; D010091:Oximes / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
D000588:Amines; D010091:Oximes; D010720:Phosphines; D012428:Ruthenium