[Prooxidant-antioxidant condition under increased convulsive activity].
During the clinical-biochemical research it was found that the trand's manner of epileptic disease in general is determined by the oxidative-antioxidant balance condition in the sick organism. The experimental research, made on rats, which were under bemegrid kindling confirmed the supposition that the pro-antioxidant brain balance disruption is one of the major factors in the increased convulsive activity development and probably plays the key role in the genesis and clinical revelation of epilepsy.
Sutkovoĭ
D A
DA
Romodanov Institute of Neurosurgery, Kiev.
Laponohov
O O
OO
Huk
A P
AP
Fedosenko
T M
TM
Makarova
T A
TA
Dmytrenko
A B
AB
Milkovs'ka
N V
NV
Sutkovoĭ
A D
AD
D000818:Animals; D001921:Brain / Q000201:enzymology; D002374:Catalase / Q000378:metabolism; D004827:Epilepsy / Q000097:blood*; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism
D008315:Malondialdehyde; D002374:Catalase; D013482:Superoxide Dismutase