title: Open mesh versus non-mesh repair of groin hernia: meta-analysis of randomised trials based on individual patient data [corrected].
abstract: BACKGROUND
  The EU Hernia Trialists Collaboration was established to provide reliable evaluation of newer methods of groin hernia repair. It involved 70 investigators in 20 countries.
  
  
  METHODS
  Twenty eligible trials (5016 participants) of open mesh vs. non-mesh groin hernia repair were identified. Meta-analysis was performed using raw individual patient data where possible.
  
  
  RESULTS
  Fewer hernia recurrences were reported after mesh repair. There were no clear differences between mesh and non-mesh groups in complications. Overall, those in the mesh groups had a shorter hospital stay, quicker return to usual activities and less frequent persisting pain, but individual trial results varied.
  
  
  CONCLUSIONS
  The review provides strong evidence that open mesh repair is associated with a reduction in the risk of recurrence of between 50% and 75%. There is also some evidence of quicker recovery and of lower rates of persisting pain following open mesh repair.
authors.affiliation: Health Services Research Unit, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, UK. a.grant@abdn.ac.uk
authors.forename: A M
authors.initials: AM
authors.lastname: Grant
mesh_terms: D006119:Groin; D059685:Herniorrhaphy; D006801:Humans; D010149:Postoperative Pain / Q000209:etiology; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D013526:Surgical Mesh; D013514:Surgical Procedures, Operative / Q000009:adverse effects / Q000379:methods*