ProDom: automated clustering of homologous domains.
The ProDom database is a comprehensive set of protein domain families automatically generated from the SWISS-PROT and TrEMBL sequence databases. An associated database, ProDom-CG, has been derived as a restriction of ProDom to completely sequenced genomes. The ProDom construction method is based on iterative PSI-BLAST searches and multiple alignments are generated for each domain family. The ProDom web server provides the user with a set of tools to visualise multiple alignments, phylogenetic trees and domain architectures of proteins, as well as a BLAST-based server to analyse new sequences for homologous domains. The comprehensive nature of ProDom makes it particularly useful to help sustain the growth of InterPro.
Servant
Florence
F
SWISSPROT Group, EBI.
Bru
Catherine
C
Carrère
Sébastien
S
Courcelle
Emmanuel
E
Gouzy
Jérĵme
J
Peyruc
David
D
Kahn
Daniel
D
D030562:Databases, Protein; D016678:Genome; D007255:Information Services; D020407:Internet; D008958:Models, Molecular; D010802:Phylogeny; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000145:classification; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein; D014584:User-Computer Interface
D011506:Proteins