[A clinical study on male patients with systemic lupus erythema].
To know the clinical characteristics of male patients with systemic lupus erythema(SLE), the clinical and laboratory indications of 46 male SLE patients were analysed and compared with those of 269 females. The results showed that: 1. There was family history in 21.28% of male patients. 2. As compared with female SLE patients, pleurisy, pericarditis, lupus nephritis(LN), proteinuria, renal failure, the incidence of types, V-LN and the positive rate of Sm antibody were more common in males while facial erythema, Raynaud's phenomenon and photoallergy were less in male. There were statistical differences between the male and female. 3. The confirmed diagnosis for the male SLE was delayed. The recovery rate was lower and the mortality was higher in males. These findings suggest that evident genetic predisposition, atypical clinical manifestations, serious renal injury and the worse prognosis are the characteristics of male SLE.
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Department of Internal Medicine, Xiangya Hospital, Hunan Medical University, Changsha 410008.
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D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000235:genetics; D008181:Lupus Nephritis / Q000175:diagnosis / Q000235:genetics; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012737:Sex Factors