title: Large-scale Homologous Analysis of Genome Sequence.
abstract: We described a new method for the large-scale homologous analysis of genome sequences, which used hashing technique combined with sparse dynamic programming to get a sequence alignment. Three examples, the plant chloroplast genomes, the mammalian T-cell receptors C(alpha)/C(delta) gene loci and the mammalian gamma-crystallin gene clusters were analysed. The results showed that the method was more rapid to obtain accurate enough data and might be useful in genome analysis.
authors.affiliation: Shanghai Institute of Biochemistry, Academia Sinica, Shanghai 200031, China.
authors.forename: Hai-Xu
authors.initials: HX
authors.lastname: Tang
authors.forename: Da-Fu
authors.initials: DF
authors.lastname: Ding