title: Protein-losing cytomegalovirus gastritis in a patient with Stevens-Johnson syndrome.
abstract: We present a case of protein-losing cytomegalovirus gastritis in a previously immunocompetent 14-year-old Japanese girl that occurred during treatment of drug (zonisamide)-induced Stevens-Johnson syndrome with hepatic failure. Her hepatic failure and symptoms of Stevens-Johnson syndrome were successfully treated with intravenous prednisolone and infusion of fresh-frozen plasma or albumin, as the occasion demanded. However, during the course of treatment, she complained of severe epigastralgia together with hypoproteinemia, and cytomegalovirus gastritis was found by endoscopic and histological examinations. The possible mechanism by which cytomegalovirus gastritis occurred in the present case and effective diagnostic procedures are discussed.
authors.affiliation: Department of Pediatrics, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: Mikio
authors.initials: M
authors.lastname: Yoshioka
authors.forename: Nobuhisa
authors.initials: N
authors.lastname: Ishiguro
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Ma
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kikuta
authors.forename: Junichi
authors.initials: J
authors.lastname: Kodaira
authors.forename: Tomoo
authors.initials: T
authors.lastname: Itoh
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Kobayashi
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005756:Gastritis / Q000150:complications* / Q000382:microbiology; D005773:Gastroscopy; D006801:Humans; D007121:Immunocompetence; D007555:Isoxazoles / Q000009:adverse effects*; D011504:Protein-Losing Enteropathies / Q000150:complications* / Q000175:diagnosis; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000150:complications*; D000078305:Zonisamide
chemical_list: D000927:Anticonvulsants; D007555:Isoxazoles; D000078305:Zonisamide