title: Prominent matched hypoperfusion in an intact cerebellum after a solitary middle cerebellar peduncle infarct.
abstract: We examined the cerebellar metabolism of a 61-year-old man with a small infarct in the left middle cerebellar peduncle and an intact cerebellum. Positron emission tomographic images obtained 28 days after onset showed prominent hypoperfusion and hypometabolism (almost 50% below the normal level) in the left cerebellar hemisphere. This case report shows that neural deafferentation may cause prominent hypometabolism without morphologic changes in the cerebellum. An arrest in synaptic activity may be the most important factor for the adaptive decrease in oxygen metabolism seen in ischemic brain.
authors.affiliation: Department of Neurology and Cerebrovascular Disease, Osaka University Hospital, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Takasawa
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kitagawa
authors.forename: Toshiho
authors.initials: T
authors.lastname: Ohtsuki
authors.forename: Naohiko
authors.initials: N
authors.lastname: Oku
authors.forename: Kazuo
authors.initials: K
authors.lastname: Hashikawa
authors.forename: Saburo
authors.initials: S
authors.lastname: Sakoda
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Hori
authors.forename: Masayasu
authors.initials: M
authors.lastname: Matsumoto
mesh_terms: D020520:Brain Infarction / Q000175:diagnosis / Q000378:metabolism*; D002531:Cerebellum / Q000098:blood supply* / Q000378:metabolism; D002540:Cerebral Cortex / Q000098:blood supply / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D014055:Tomography, Emission-Computed
chemical_list: D010100:Oxygen