The Self-association of Melittin at Low Concentration in Aqueous Solution.
The intrinsic fluorescence emission, polarization and Trp-19 quenching of melittin in the aqueous solution showed that even with concentration as low as 2 &mgr;M, the self-association of melittin still occurred. The transition preferred to occur under acidic condition and the stability of the associated melittin was dependent on the pH value of the solution.
Han
Xue-Hai
XH
National laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China.
Sui
Seng-Fang
SF