Changes in fibrinogen level in liver cirrhosis.
BACKGROUND
Liver cirrhosis causes significant morbidity and mortality in our country, however early diagnosis prevents complications and carries good prognosis. Estimation of fibrinogen level may be helpful in preventing bleeding tendencies.


METHODS
Plasma fibrinogen level of 82 confirmed liver cirrhosis in 18-60 years age admitted patients of Khyber Teaching Hospital were determined and compared with normal controls, to establish it as a marker for diagnosis in cirrhosis liver and prognosis. Fibrinogen level was determined by Fibriprest-2.


RESULTS
Significantly low levels in patients were recorded as compared to controls. 40% cases showed low fibrinogen level, while nearly 44% had normal levels.


CONCLUSIONS
Fibrinogen level was low in early and terminal cirrhosis and high in advancing cirrhosis as compared to controls that showed normal levels.
Arif
Saatea
S
Department of Biochemistry, Khyber Medical College, University of Peshawar, Pakistan.
Khan
A Sattar
AS
Khan
Arif Raza
AR
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005340:Fibrinogen / Q000032:analysis*; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood*; D008297:Male; D008875:Middle Aged
D005340:Fibrinogen