[Study of plasma neuron-specific enolase activity of patients with chronic pulmonary heart disease complicated by pulmonary encephalopathy].
The plasma neuron-specific enolase (NSE) activity in the 15 patients of chronic pulmonary heart disease complicated by pulmonary encephalopathy and 10 chronic pulmonary heart disease without pulmonary encephalopathy (controls) were detected. The results showed that NSE activity in patients with moderate, severe pulmonary encephalopathy were significantly higher than those of patients with mild pulmonary encephalopathy, stable patients and controls. The plasma NSE activity from the patients with pulmonary encephalopathy were negatively correlated with the PaO2 and were positively correlated with PaCO2. This study suggests that plasma NSE activity may reflect the degree of brain damage by chronic hypoxia and remain of CO2 in the patients with chronic pulmonary heart disease.
Liu
J Y
JY
College of Nursing, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Yang
H Z
HZ
Yian
G M
GM
D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000201:enzymology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010751:Phosphopyruvate Hydratase / Q000097:blood*; D011660:Pulmonary Heart Disease / Q000150:complications / Q000201:enzymology*
D010751:Phosphopyruvate Hydratase