title: Changes in fibrinogen level in liver cirrhosis.
abstract: BACKGROUND
  Liver cirrhosis causes significant morbidity and mortality in our country, however early diagnosis prevents complications and carries good prognosis. Estimation of fibrinogen level may be helpful in preventing bleeding tendencies.
  
  
  METHODS
  Plasma fibrinogen level of 82 confirmed liver cirrhosis in 18-60 years age admitted patients of Khyber Teaching Hospital were determined and compared with normal controls, to establish it as a marker for diagnosis in cirrhosis liver and prognosis. Fibrinogen level was determined by Fibriprest-2.
  
  
  RESULTS
  Significantly low levels in patients were recorded as compared to controls. 40% cases showed low fibrinogen level, while nearly 44% had normal levels.
  
  
  CONCLUSIONS
  Fibrinogen level was low in early and terminal cirrhosis and high in advancing cirrhosis as compared to controls that showed normal levels.
authors.affiliation: Department of Biochemistry, Khyber Medical College, University of Peshawar, Pakistan.
authors.forename: Saatea
authors.initials: S
authors.lastname: Arif
authors.forename: A Sattar
authors.initials: AS
authors.lastname: Khan
authors.forename: Arif Raza
authors.initials: AR
authors.lastname: Khan
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005340:Fibrinogen / Q000032:analysis*; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D005340:Fibrinogen