Synthesis and absolute configuration of lactone II isolated from Streptomyces sp. Go 40/10.
All four possible stereoisomers of lactone II isolated from Streptomyces sp. Go 40/10, an autoregulator, have been efficiently synthesized in a stereoselective manner starting from (S)-malic acid and sorbic acid, and the absolute configuration was determined to be 2S, 3S, 9R, 10S.
Ueki
T
T
Department of Chekistry,Graduate School of Science, Osaka City University, Sugimoto-cho, Sumiyoshi-ku, Osaka 558-8585, Japan.
Morimoto
Y
Y
Kinoshita
T
T
D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry*
D007783:Lactones; C467817:lactone II