title: Stereoselective total synthesis of (+)-myriocin from D-mannose.
abstract: The stereoselective total synthesis of myriocin 1 from D-mannose is described; the carbon framework with three contiguous chiral centers including a tetra-substituted carbon with nitrogen was effectively constructed using Overman rearrangement as the key reaction.
authors.affiliation: Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Oishi
authors.forename: K
authors.initials: K
authors.lastname: Ando
authors.forename: N
authors.initials: N
authors.lastname: Chida
mesh_terms: D005229:Fatty Acids, Monounsaturated / Q000138:chemical synthesis* / Q000737:chemistry; D007166:Immunosuppressive Agents / Q000138:chemical synthesis* / Q000737:chemistry; D008358:Mannose / Q000737:chemistry*; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: D005229:Fatty Acids, Monounsaturated; D007166:Immunosuppressive Agents; D008358:Mannose; C001996:thermozymocidin