Fuzzy pharmacology: theory and applications.
Fuzzy pharmacology is a term coined to represent the application of fuzzy logic and fuzzy set theory to pharmacological problems. Fuzzy logic is the science of reasoning, thinking and inference that recognizes and uses the real world phenomenon that everything is a matter of degree. It is an extension of binary logic that is able to deal with complex systems because it does not require crisp definitions and distinctions for the system components. In pharmacology, fuzzy modeling has been used for the mechanical control of drug delivery in surgical settings, and work has begun evaluating its use in other pharmacokinetic and pharmacodynamic applications. Fuzzy pharmacology is an emerging field that, based on these initial explorations, warrants further investigation.
Sproule
Beth A
BA
Centre for Addiction and Mental Health, 33 Russell Street, Ontario, M5S 2S1, Toronto, Canada. beth_sproule@camh.net
Naranjo
Claudio A
CA
Türksen
I Burhan
IB
D000818:Animals; D016503:Drug Delivery Systems; D017143:Fuzzy Logic; D006801:Humans; D008954:Models, Biological; D010600:Pharmacology / Q000639:trends*