title: Efficient synthesis of the antigenic phosphoglycans of the Leishmania parasite.
abstract: Antigenic phosphoglycan repeats of the Leishmania parasite can be assembled in a flexible and efficient manner without involving any glycosidation steps, and the chain can be extended either towards the non-reducing (6'-OH) or reducing (1-OH) end suitable for synthesis of lipophosphoglycan, proteophosphoglycan and analogues.
authors.affiliation: Bio-organic Chemistry Lab, National Institute of Immunology, Aruna Asaf Ali Marg, JNU Complex, New Delhi 110067, India.
authors.forename: D
authors.initials: D
authors.lastname: Ruhela
authors.forename: R A
authors.initials: RA
authors.lastname: Vishwakarma
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000737:chemistry* / Q000378:metabolism; D002241:Carbohydrates / Q000737:chemistry; D006028:Glycosphingolipids / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D007891:Leishmania; D008565:Membrane Proteins / Q000737:chemistry* / Q000378:metabolism; D011509:Proteoglycans / Q000737:chemistry* / Q000378:metabolism; D015800:Protozoan Proteins
chemical_list: D000953:Antigens, Protozoan; D002241:Carbohydrates; D006028:Glycosphingolipids; D008565:Membrane Proteins; C400527:Ppg1 protein, Leishmania; D011509:Proteoglycans; D015800:Protozoan Proteins; C008290:lipophosphonoglycan