title: Sequence fidelity of a template-directed PNA-ligation reaction.
abstract: The ligation method and an appended duplex-stabilizing dye affect both yield and sequence selectivity of a template-controlled PNA-ligation. The highest selectivity was obtained with a peptide condensation that formed an abasic site.
authors.affiliation: Max-Planck-Institut für Molekulare Physiologie, Otto-Hahn-Str. 11, D-44227 Dortmund, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Mattes
authors.forename: O
authors.initials: O
authors.lastname: Seitz
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D009841:Oligonucleotides / Q000737:chemistry / Q000378:metabolism; D020135:Peptide Nucleic Acids / Q000737:chemistry / Q000378:metabolism*; D013379:Substrate Specificity; D013698:Templates, Genetic
chemical_list: D009841:Oligonucleotides; D020135:Peptide Nucleic Acids