title: An efficient synthesis of novel carbocyclic nucleosides with use of ring-closing metathesis from D-lactose.
abstract: This paper describes an efficient synthetic route for various types of novel carbocyclic nucleosides. The required stereochemistry of the targeted nucleosides was successfully obtained with use of Grubbs cyclization and Trost allylic alkylation from the carbohydrate chiral template "D-lactose".
authors.affiliation: College of Pharmacy and College of Education, Chosun University, Kwangju 501-759, South Korea. hongjh@mail.chosun.ac.kr
authors.forename: Joon Hee
authors.initials: JH
authors.lastname: Hong
authors.forename: Myung Jung
authors.initials: MJ
authors.lastname: Shim
authors.forename: Bong Oh
authors.initials: BO
authors.lastname: Ro
authors.forename: Ok Hyun
authors.initials: OH
authors.lastname: Ko