title: Application of clenbuterol in the treatment of urinary incontinence.
abstract: The treatment of urinary incontinence represents an important medico-social problem, notwithstanding the offered 90 products of treatment. The authors summarice their experience on the treatment of urinary incontinence with clenbuterol for the period 1988-1997. During this period total of 335 patients (163 women and 72 men), aged between 30 and 73 were treated. The medicine was used in the treatment of women with stress incontinence (60) and urge incontinence (103). In cases of combination between urinary incontinence and hyperreflexy of the detrusor, and antiholynergic therapy was used. It was used after surgery of the adenoma of the prostate in men, aged 62-73: in 50 of them after transvesical prostatectomy, and in 22 after transurethral resection of the prostate. The authors determine the period of using the product in the different kinds of incontinence. Clenbuterol can be effective only when sfincter activity is preserved, which is proved by means of urodynamic tests. The durability of treatment was stable in 86% of treated women, and in 76.3% of treated men. The authors determine the indications and contraindications of administration of celbuterol. They analise the changes in the hydrodynamic of the lower urinary tract in the patients with urinary incontinence after clenbuterol therapy.
authors.affiliation: Institute N.I. Pirogoff Hospital, Scientific Institute of Emergency Medicine, Section for Adults and Children, Sofia, Bulgaria.
authors.forename: B
authors.initials: B
authors.lastname: Zozikov
authors.forename: S I
authors.initials: SI
authors.lastname: Kunchev
authors.forename: C
authors.initials: C
authors.lastname: Varlev
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D001561:Benzilates / Q000627:therapeutic use; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D002976:Clenbuterol / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000188:drug therapy*; D014563:Urodynamics
chemical_list: D000318:Adrenergic beta-Agonists; D001561:Benzilates; D018680:Cholinergic Antagonists; C015586:propiverine; D002976:Clenbuterol