title: Rate-dependent changes in atrial action potential duration after short- duration rapid atrial pacing in humans.
abstract: The effect of rapid atrial pacing on the rate adaptation of the atrial action potential duration was studied in humans. The right atrial monophasic action potential (RAMAP) of 5 patients was recorded before and after 30 min of rapid atrial pacing. The pacing cycle length (CL) was 146 +/- 9 ms, the shortest duration at which 1:1 capture was possible. The RAMAP duration at 90% repolarization (RMAPD) was measured. CL-dependent changes in RAMAPD (CL 600 ms-CL 300 ms) before and after rapid atrial pacing were 51.8 +/- 10.7 ms and 30.8 +/- 7.6 ms (p < 0.05), respectively.
authors.affiliation: Second Department of Medicine, Nihon University School of Medicine, Tokyo, Japan. iwatanab@med.nihon-u.ac.jp
authors.forename: Ichiro
authors.initials: I
authors.lastname: Watanabe
authors.forename: Riko
authors.initials: R
authors.lastname: Masaki
authors.forename: Kimie
authors.initials: K
authors.lastname: Ohkubo
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Okumura
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamada
authors.forename: Naohiro
authors.initials: N
authors.lastname: Oshikawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Saito
authors.forename: Yukio
authors.initials: Y
authors.lastname: Ozawa
authors.forename: Katsuo
authors.initials: K
authors.lastname: Kanmatsuse
mesh_terms: D000200:Action Potentials; D000328:Adult; D001281:Atrial Fibrillation / Q000503:physiopathology* / Q000628:therapy; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004562:Electrocardiography; D022062:Electrophysiologic Techniques, Cardiac; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged