Effects of the N-salicylaladehyde Aminoglucose Schiff Base Complexes no O(2)(-). and DNA.
The effects of SG schiff base complexes with Cu(II), Zn(II), Co(III) on O(2)(-). and DNA were studied. The results showed that both CuSG and ZnSG could an inhibit the synthesis of O(2)(-). markedly. The inhibiting effect of CuSG was larger than that of ZnSG. Complexes CuSG and CoSG could also combine with the salmon sperm DNA. The intrinsic association constant (K(0)) for CuSG and CoSG were estimated to be 2.86x10(4) M(-1 and 1.29x105) M-1 respectively. The numbers of binding sites per 100 nucleotide (n) were 2.5 and 7.5 respectively.
Liu
Xiao-Qin
XQ
Hubei Sanxia College Medical College, Yichang 443003, China.
Wang
Jian-Lin
JL
Le
Zhi-Feng
ZF
Feng
Chang-Jian
CJ
Shen
Hao-Yu
HY
Zhang
Xiang-Cai
XC