Pustular miliaria rubra: a specific cutaneous finding of type I pseudohypoaldosteronism.
Type I pseudohypoaldosteronism, an autosomal recessive, life-threatening disorder of mineralocorticoid resistance leads to excessive loss of sodium chloride through eccrine and other secretions. Recurrent episodes of pustular miliaria rubra are associated with salt-losing crises and clear spontaneously with stabilization. Inflammation of and around the damaged eccrine glands has been attributed to the deleterious effects of excessive eccrine gland salt exposure.
Urbatsch
Amy
A
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
Paller
Amy S
AS
D018450:Disease Progression; D006801:Humans; D007223:Infant; D008297:Male; D008883:Miliaria / Q000150:complications / Q000175:diagnosis*; D011379:Prognosis; D011546:Pseudohypoaldosteronism / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D012008:Recurrence; D018570:Risk Assessment; D012720:Severity of Illness Index; D014883:Water-Electrolyte Imbalance / Q000175:diagnosis