[Clinical pathology study of lingual carcinoma treatment with CDDP-AMS microcapsules through lingual artery].
11 patients with lingual carcinoma were treated by artery chemoembolization with 100 mg CDDP-AMS microcapsules (CDDP 13.6 mg) through lingual artery, and the average diameter of microcapsules was 56.3 microns. There was no obvious carcinoma cell or carcinoma tissue in pathologic specimens of the tissue after 4 weeks of treatment. After 5-6 weeks of chemoembolization, the clinical tumor ulcer disappeared, but it was difficult to judge the change of the tumor because of local fiber tissue. After 6 months, by observation of 4 patients whose tumors had not been excised, it was found that the infiltuation mass of primary carcinoma disappeared and tongue body became soft. It suggests that artery chemoembolization with CDDP-AMS microcapsules is an efficient way of lingual carcinoma treatment.
Wang
C
C
College of Stomatology, West China University of Medical Sciences.
Li
H
H
Wen
Y
Y
D000328:Adult; D000368:Aged; D000418:Albumins; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D001158:Arteries; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology; D002945:Cisplatin / Q000008:administration & dosage*; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D014059:Tongue / Q000098:blood supply*; D014062:Tongue Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
D000418:Albumins; D000970:Antineoplastic Agents; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D002945:Cisplatin