title: Cystic fibrosis presenting as fetal anemia. A case report.
abstract: BACKGROUND
  Cystic fibrosis in the fetus may present with meconium ileus, seen as dilated, hyperechogenic bowel on the prenatal ultrasound examination. Rarely does in utero bowel perforation occur with resulting peritoneal echogenicity, ascites or lack of bowel dilation.
  
  
  METHODS
  In a case of cystic fibrosis in a fetus, all three findings above occurred, as did anemia, most likely secondary to bleeding from perforated bowel. The anemia was detected following the finding of significantly elevated peak flow velocity in the middle cerebral artery (MCA).
  
  
  CONCLUSIONS
  Fetuses with cystic fibrosis can develop anemia. MCA peak flow velocity measurements are helpful in detecting the anemia.
authors.affiliation: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, University of Iowa, Iowa City, IA, USA. asha-rijhsinghani@uiowa.edu
authors.forename: Asha
authors.initials: A
authors.lastname: Rijhsinghani
authors.forename: Wendy F
authors.initials: WF
authors.lastname: Hansen
authors.forename: Bick
authors.initials: B
authors.lastname: Phan
mesh_terms: D000328:Adult; D000740:Anemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D001783:Blood Flow Velocity / Q000502:physiology; D003550:Cystic Fibrosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D011247:Pregnancy; D014463:Ultrasonography