Chemical modification of schizophyllan by introduction of a cationic charge into the side chain which enhances the thermal stability of schizophyllan-poly(C) complexes.
Combining oxidation with periodate and reductive amination, the amino group is introduced only in the side chain of schizophyllan and the product can bind to poly(C) with a higher dissociation temperature than that of the unmodified schizophyllan and poly(C) complex.
Koumoto
K
K
Chemotransfiguration Project, PRESTO, Japan Science and Technology Corporation, Kurume Research Center Building, 2432 Aikawa Kurume, Fukuoka 839-0861, Japan.
Kimura
T
T
Mizu
M
M
Sakurai
K
K
Shinkai
S
S
D000586:Amination; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry*; D002412:Cations / Q000737:chemistry; D002942:Circular Dichroism; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D010504:Periodic Acid / Q000737:chemistry; D011066:Poly C / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry*; D012566:Sizofiran / Q000737:chemistry*; D013816:Thermodynamics
D000972:Antineoplastic Agents, Phytogenic; D002412:Cations; D011134:Polysaccharides; D010504:Periodic Acid; D011066:Poly C; D012566:Sizofiran; C009288:metaperiodate