title: Antimicrobial and antifungal activity of crude extracts and isolated saponins from Astragalus verrucosus.
abstract: The antimicrobial and antifungal properties of several crude extracts and pure saponins, astraverrucins I-VI, from the aerial parts of Astragalus verrucosus were investigated by the disc diffusion method. Antimycotic activity was observed on more polar extracts, but only one saponin showed an appreciable activity.
authors.affiliation: Dipartimento di Chimica Bioorganica e Biofarmacia, via Bonanno 33, 56126 Pisa, Italy. luipi@farm.unipi.it
authors.forename: Luisa
authors.initials: L
authors.lastname: Pistelli
authors.forename: Alessandra
authors.initials: A
authors.lastname: Bertoli
authors.forename: Elena
authors.initials: E
authors.lastname: Lepori
authors.forename: Ivano
authors.initials: I
authors.lastname: Morelli
authors.forename: Lirio
authors.initials: L
authors.lastname: Panizzi
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D007887:Fabaceae; D005658:Fungi / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D010936:Plant Extracts