Diagnosis and treatment of Aspergillus flavus sternal wound infections after cardiac surgery.
We report the clinical data for 9 patients affected during an outbreak of Aspergillus flavus sternal wound infections after cardiac surgery. In 7 patients, the infection had a locally invasive character, with 3 of these patients having multiple relapses; 2 patients had fulminant mediastinitis and died. Most patients received combined surgical and medical treatment.
Vandecasteele
S J
SJ
Department of Internal Medicine-Infectious Diseases, University Hospital of Leuven, 3000 Leuven, Belgium. Stefaan.Vandecasteele@uz.kuleuven.ac.be
Boelaert
J R
JR
Verrelst
P
P
Graulus
E
E
Gordts
B Z
BZ
D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D001231:Aspergillus flavus / Q000302:isolation & purification*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D013903:Thoracic Surgery; D016896:Treatment Outcome