title: [Surgical treatment of pleural metastases in breast cancer].
abstract: Pleural metastases of breast cancer is a severe progression of the disease and the treatment is difficult. Distant metastases are mainly treated by chemo-, radio- or hormone therapy, but in recent years surgical intervention is increasingly important. Between the 1st of January 1992 and 31st of December 2001 in the 2nd Department of Surgery University of Debrecen Medical and Health Science Center Medical School of Medicine 43 patients with breast cancer were operated on because of pleural metastases. In these patients biopsy and pleurodesis with talcum insufflation were performed. The surgical treatment was followed by chemotherapy. Pleurodesis was successful at 76.7 percent. The 6, 12 and 24 months survival was 58.1, 39.5 and 16.3 percent. Based on literature data and own experience we conclude that surgical intervention with adjuvant therapy extends life expectancy for patients with pleural metastases. Pleurodesis can prevent or delay hydrothorax, it improves vital functions and the quality of life for patients with pleural metastases.
authors.affiliation: Debreceni Egyetem Orvos- és Egészségtudományi Centrum, II. sz. Sebészeti Klinika, 4004 Debrecen.
authors.forename: László
authors.initials: L
authors.lastname: Halász
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Szentkereszty
authors.forename: Andrea
authors.initials: A
authors.lastname: Furka
authors.forename: Sándor
authors.initials: S
authors.lastname: Kiss
authors.forename: Sándor
authors.initials: S
authors.lastname: Kollár
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery* / Q000628:therapy; D018700:Pleurodesis; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents