Three-dimensional prenatal diagnosis of frontonasal malformation and unilateral cleft lip/palate.
Frontonasal malformation includes a spectrum of anomalies involving the eyes, nose, lips, forehead and brain. We present a case in which a fetal labial cleft was initially identified using traditional two-dimensional sonography. Three-dimensional sonography with multiplanar reconstruction and surface-rendering were essential to establish the diagnosis of frontonasal malformation with severe nasal hypoplasia and unilateral complete cleft lip/palate.
Shipp
T D
TD
Department of Obstetrics and Gynecology, Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. tshipp@partners.org
Mulliken
J B
JB
Bromley
B
B
Benacerraf
B
B
D000328:Adult; D002971:Cleft Lip / Q000000981:diagnostic imaging*; D002972:Cleft Palate / Q000000981:diagnostic imaging*; D005260:Female; D005624:Frontal Bone / Q000002:abnormalities*; D006801:Humans; D021621:Imaging, Three-Dimensional; D009666:Nose / Q000002:abnormalities*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal