Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).
Dresser
Mark J
MJ
Department of Biopharmaceutical Sciences, University of California, San Francisco, 94143-0446, USA.
Xiao
Guangqing
G
Leabman
Maya K
MK
Gray
Andrew T
AT
Giacomini
Kathleen M
KM
D000818:Animals; D001645:Biguanides / Q000737:chemistry / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D027701:Organic Cation Transport Proteins / Q000378:metabolism*; D000075102:Organic Cation Transporter 2; D000644:Quaternary Ammonium Compounds / Q000737:chemistry / Q000493:pharmacokinetics*; D014982:Xenopus laevis
D001645:Biguanides; D027701:Organic Cation Transport Proteins; D000075102:Organic Cation Transporter 2; D000644:Quaternary Ammonium Compounds; C491013:SLC22A2 protein, human