Representation of the quantity of visual items in the primate prefrontal cortex.
Deriving the quantity of items is an abstract form of categorization. To explore it, monkeys were trained to judge whether successive visual displays contained the same quantity of items. Many neurons in the lateral prefrontal cortex were tuned for quantity irrespective of the exact physical appearance of the displays. Their tuning curves formed overlapping filters, which may explain why behavioral discrimination improves with increasing numerical distance and why discrimination of two quantities with equal numerical distance worsens as their numerical size increases. A mechanism that extracts the quantity of visual field items could contribute to general numerical ability.
Nieder
Andreas
A
Picower Center for Learning and Memory, RIKEN-MIT Neuroscience Research Center, and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. nieder@mit.edu
Freedman
David J
DJ
Miller
Earl K
EK
D000818:Animals; D007858:Learning / Q000502:physiology; D008253:Macaca mulatta; D008433:Mathematics; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology; D017397:Prefrontal Cortex / Q000166:cytology / Q000502:physiology*; D013850:Thinking / Q000502:physiology; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology