title: Obese, older adults with knee osteoarthritis: weight loss, exercise, and quality of life.
abstract: This study examined the effects of dietary weight loss and exercise on the health-related quality of life (HRQL) of overweight and obese, older adults with knee osteoarthritis. A total of 316 older men and women with documented evidence of knee osteoarthritis were randomly assigned to 1 of 4 18-month interventions: dietary weight loss, exercise, dietary weight loss and exercise, or healthy lifestyle control. Measures included the SF-36 Health Survey and satisfaction with body function and appearance. Results revealed that the combined diet and exercise intervention had the most consistent, positive effect on HRQL compared with the control group; however, findings were restricted to measures of physical health or psychological outcomes that are related to the physical self.
authors.affiliation: Department of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina 27109, USA. rejeski@wfu.edu
authors.forename: W Jack
authors.initials: WJ
authors.lastname: Rejeski
authors.forename: Brian C
authors.initials: BC
authors.lastname: Focht
authors.forename: Steven P
authors.initials: SP
authors.lastname: Messier
authors.forename: Tim
authors.initials: T
authors.lastname: Morgan
authors.forename: Marco
authors.initials: M
authors.lastname: Pahor
authors.forename: Brenda
authors.initials: B
authors.lastname: Penninx
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D004038:Diet, Reducing / Q000523:psychology; D015444:Exercise / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000523:psychology / Q000628:therapy*; D020370:Osteoarthritis, Knee / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life / Q000523:psychology*; D016037:Single-Blind Method; D015431:Weight Loss