[Establishment of a heterologous graft model for human breast infiltrating duct carcinoma in nude mice].
A heterologous graft model for human breast infiltrating duct carcinoma is reported in this paper. The grafts derived from an infiltration duct carcinoma of a patient's right breast and her metastatic lymphnode mass were transplanted into the breast pads of nude mice in 1996, and the carcinoma masses were found in breast pads 31 days later. By now, the grafts of carcinoma have been transplanted into nude mice for 15 passages with a full success in 59 mice and with the biological characteristics of the original breast carcinoma. This heterologous graft model was established for the first time in China and the results suggest it be a good model for further research of breast carcinoma.
Bai
S
S
Laboratory Animal Center, WCUMS, Chengdu 610041.
Zhao
Y
Y
Zhang
X
X
Li
H
H
Jing
J
J
Xie
C
C
Chen
G
G
D000818:Animals; D001943:Breast Neoplasms; D018270:Carcinoma, Ductal, Breast; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D009368:Neoplasm Transplantation