title: Beta- and alpha-globin genotypes in Albanian patients affected by beta-globin gene disorders.
abstract: We investigated the molecular basis of hemoglobinopathies and restriction fragment length polymorphism (RFLP) haplotypes in 58 unrelated Albanian patients. A wise heterogeneity was detected, characterized by 11 beta-thalassemia, 3 Hb variant and 4 alpha-globin alleles. All beta-thalassemia and Hb variant alleles were associated with the same haplotypes described in other populations. Genotype-phenotype correlation was established.
authors.forename: Maria
authors.initials: M
authors.lastname: De Angioletti
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Lacerra
authors.forename: Enis
authors.initials: E
authors.lastname: Boletinio
authors.forename: Francesca
authors.initials: F
authors.lastname: Di Noce
authors.forename: Gennaro
authors.initials: G
authors.lastname: Musollino
authors.forename: Clementina
authors.initials: C
authors.lastname: Carestia
mesh_terms: D000415:Albania / Q000453:epidemiology; D000483:Alleles; D005838:Genotype; D005914:Globins / Q000235:genetics*; D006239:Haplotypes / Q000235:genetics; D006453:Hemoglobinopathies / Q000453:epidemiology / Q000235:genetics*; D006801:Humans
chemical_list: D005914:Globins