Pityriasis rosea associated with imatinib (STI571, Gleevec).
A tyrosine kinase inhibitor (STI571, Gleevec) has recently been applied in the treatment of chronic myeloid leukemia. We present the first reported case of pityriasis rosea occurring as a reaction to Gleevec in a woman with blast crisis of this disorder. It is suggested that although coincidental, this exanthem may be due to this agent.
Konstantopoulos
K
K
First Department of Medicine, University of Athens School of Medicine at Laikon Hospital, Athens, Greece. kkonstan@med.uoa.gr
Papadogianni
A
A
Dimopoulou
M
M
Kourelis
C
C
Meletis
J
J
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001549:Benzamides; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D000068877:Imatinib Mesylate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy; D010879:Piperazines / Q000009:adverse effects*; D017515:Pityriasis Rosea / Q000139:chemically induced*; D011743:Pyrimidines / Q000009:adverse effects*
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate