Malignant fibrous histiocytoma arising on chronic osteomyelitis.
We present a case of a primary malignant fibrous histiocytoma of the skin (MFH) arising on chronic osteomyelitis in a 67-year-old woman. Although this condition seems to be a predisposing factor for the onset of the malignancy, MFH complicating chronic osteomyelitis is generally localized at the level of the bone tissue. In the case we report the neoplasm was primitively localized at the dermal and subcutaneous level and presented as a rapidly growing mass.
Foti
C
C
Department of Internal Medicine, Immunology and Infectious Diseases, University of Bari, Italy. c.foti@dermatologia.uniba.it
Giannelli
G
G
Berloco
A
A
Mascolo
V
V
Ingravallo
G
G
Giardina
C
C
D000368:Aged; D001707:Biopsy, Needle; D002908:Chronic Disease; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D010019:Osteomyelitis / Q000175:diagnosis / Q000473:pathology*; D011230:Precancerous Conditions / Q000473:pathology*; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D013978:Tibial Fractures