title: Lemierre's disease caused by co-infection of Arcanobacterium haemolyticum and Fusobacterium necrophorum: a case report.
abstract: We report the first case of Lemierre's disease caused by a co-infection with A. haemolyticum and F. necrophorum. A characteristic skin rash and predominant growth on multiple blood cultures suggests a causative role for Arcanobacterium. Failures of penicillin therapy in A. haemolyticum infections should be considered when the initial antibiotic regimen is chosen.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, Franklin Square Hospital Center, Baltimore, MD 21237, USA. dryounos@hotmail.com
authors.forename: F
authors.initials: F
authors.lastname: Younus
authors.forename: A
authors.initials: A
authors.lastname: Chua
authors.forename: G
authors.initials: G
authors.lastname: Tortora
authors.forename: V E
authors.initials: VE
authors.lastname: Jimenez
mesh_terms: D000192:Actinomycetales / Q000502:physiology*; D000193:Actinomycetales Infections / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005674:Fusobacterium Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007601:Jugular Veins / Q000382:microbiology* / Q000473:pathology; D008297:Male; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010878:Piperacillin / Q000627:therapeutic use; D000077725:Piperacillin, Tazobactam Drug Combination; D018805:Sepsis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D013924:Thrombophlebitis / Q000150:complications* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000077725:Piperacillin, Tazobactam Drug Combination; D014640:Vancomycin; D010397:Penicillanic Acid; D010878:Piperacillin