title: One-pot synthesis of symmetrical and unsymmetrical bisarylethynes by a modification of the sonogashira coupling reaction.
abstract: A modification of the Sonogoshira coupling reaction employing an amidine base and a substoichiometric amount of water generates symmetrical and unsymmetrical bisarylethynylenes in one pot through in situ deprotection of trimethylsilylethynylene-added intermediates.
authors.affiliation: Department of Chemistry, Macalester College, St. Paul, Minnesota 55105, USA.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Mio
authors.forename: Lucas C
authors.initials: LC
authors.lastname: Kopel
authors.forename: Julia B
authors.initials: JB
authors.lastname: Braun
authors.forename: Tendai L
authors.initials: TL
authors.lastname: Gadzikwa
authors.forename: Kami L
authors.initials: KL
authors.lastname: Hull
authors.forename: Ronald G
authors.initials: RG
authors.lastname: Brisbois
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Markworth
authors.forename: Paul A
authors.initials: PA
authors.lastname: Grieco
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry; D006574:Heterocyclic Compounds, 2-Ring / Q000138:chemical synthesis* / Q000737:chemistry*; D008027:Light; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D012997:Solvents; D013696:Temperature
chemical_list: D006574:Heterocyclic Compounds, 2-Ring; D012997:Solvents; D010165:Palladium; D003300:Copper