Listening in on bacteria: acyl-homoserine lactone signalling.
Bacterial cell-to-cell signalling has emerged as a new area in microbiology. Individual bacterial cells communicate with each other and co-ordinate group activities. Although a lot of detail is known about the mechanisms of a few well-characterized bacterial communication systems, other systems have been discovered only recently. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs.
Fuqua
Clay
C
Department of Biology, Indiana University, Jordan Hall 142, 1001 East 3rd Street, Bloomington, Indiana 47405, USA.
Greenberg
E Peter
EP
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000096:biosynthesis / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D001419:Bacteria / Q000166:cytology / Q000201:enzymology / Q000378:metabolism* / Q000472:pathogenicity; D018441:Biofilms; D023482:Bioterrorism; D008163:Luminescent Measurements; D012097:Repressor Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D013559:Symbiosis; D015534:Trans-Activators / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
D012097:Repressor Proteins; D015534:Trans-Activators; C064778:LuxR autoinducer binding proteins; C088386:homoserine lactone; D015107:4-Butyrolactone