title: HTLV-I and HTLV-II infections in volunteer blood donors and high-risk groups in Lebanon.
abstract: A serosurvey for Human T-cell Lymphotropic virus type 1 (HTLV-I)/HTLV-II was conducted in 1,900 blood donors, 120 pregnant women and 436 high-risk group patients in Beirut, Lebanon. One of the 1,900 blood donors was anti-HTLV-I/II-seroreactive on screening by enzyme immunoassay (EIA) but was indeterminate by Western blot and negative by polymerase chain reaction. None of the other 556 subjects studied was seroreactive by EIA. The credibility of the zero prevalence of HTLV-I/II infection among the Lebanese blood donors is supported by the absence of seroreactivity of antibodies in the multiply transfused patients. It seems therefore that the prevalence of HTLV-I/II appears to be less than 1 in 2,456 in the Lebanese population and hence, HTLV-I/II infection does not appear to require routine screening in Lebanon.
authors.affiliation: Hotel Dieu de France Hospital, Beirut, Lebanon.
authors.forename: R
authors.initials: R
authors.lastname: Naman
authors.forename: S
authors.initials: S
authors.lastname: Klayme
authors.forename: M
authors.initials: M
authors.lastname: Naboulsi
authors.forename: J
authors.initials: J
authors.lastname: Mokhbat
authors.forename: O
authors.initials: O
authors.lastname: Jradi
authors.forename: S
authors.initials: S
authors.lastname: Ramia
mesh_terms: D000293:Adolescent; D000328:Adult; D001782:Blood Donors / Q000706:statistics & numerical data; D015480:Deltaretrovirus Antibodies / Q000276:immunology / Q000302:isolation & purification; D005260:Female; D015490:HTLV-I Infections / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D015491:HTLV-II Infections / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D015368:Human T-lymphotropic virus 1 / Q000276:immunology / Q000302:isolation & purification; D015367:Human T-lymphotropic virus 2 / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007861:Lebanon / Q000453:epidemiology; D008297:Male; D008403:Mass Screening; D011247:Pregnancy; D015995:Prevalence; D012307:Risk Factors
chemical_list: D015480:Deltaretrovirus Antibodies