Progestins and endometrial cancer.
Premenopausal women--especially young women--with endometrial cancer stage I may be treated successfully with progestins alone as primary therapy to preserve their child-bearing potential. There is some indication that progestins could be used in neoadjuvant fashion. Individualization of adjuvant treatment with radiation or progestins and in combination seems possible. Progestins have an established place in the palliative treatment of women with advanced cancer. In addition, progestins can be used in advanced and/or recurrent endometrial cancer in combination with chemotherapy and tamoxifen.
Schindler
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AE
Department of Obstetrics and Gynecology, University of Essen, Essen, Germany.
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D017697:Premenopause; D011372:Progestins / Q000008:administration & dosage / Q000627:therapeutic use*; D012307:Risk Factors; D013629:Tamoxifen / Q000627:therapeutic use
D004965:Estrogen Antagonists; D011372:Progestins; D013629:Tamoxifen