A novel [2 + 2 + 1]/[2 + 1] tandem cycloaddition reaction of Fischer alkynyl carbenes with strained bicyclic olefins.
The reaction of strained bicyclic olefins with alkynyl carbenes and terminal olefins involves the creation of five new sigma C-C bonds with the concomitant formation of two new rings, thus creating a complex and densely functionalized structure in a single operation.
Barluenga
José
J
Instituto Universitario de Química Organometálica "Enrique Moles", Unidad Asociada al CSIC, Universidad de Oviedo, Julián Clavería 8, 33071-Oviedo, Spain. barluenga@sauron.quimica.uniovi.es
Fernández-Rodríguez
Manuel Angel
MA
Andina
Facundo
F
Aguilar
Enrique
E