title: Comparison of spiral-computed tomography with water-filling of the stomach and endosonography for gastric lymphoma of mucosa-associated lymphoid tissue-type.
abstract: BACKGROUND
  Endosonography has been reported as the method of choice for local staging of patients with gastric lymphoma of mucosa-associated lymphoid tissue (MALT)-type. As endosonography is still restricted to specialized centers, we have investigated the use of spiral computed tomography of the abdomen with water-filling of the stomach (hydro-spiral CT) for enhanced contrast in patients with gastric lymphoma.
  
  
  METHODS
  Patients with a histological verified diagnosis of gastric lymphoma of MALT-type were included in this prospective series. All patients underwent routine staging procedures including endosonography of the upper GI-tract carried out by a single individual. In addition, patients were subjected to hydro-spiral CT either before or after endosonography within a maximal time span of 4 weeks. Results of hydro-spiral CT were compared to those of the endosonographic evaluation and histological work-up of biopsy specimens.
  
  
  RESULTS
  A total of 14 patients with primary gastric lymphoma of MALT-type (3 with a high-grade component) were studied prospectively. All patients underwent hydro-spiral CT before initiation of treatment, and 2 patients were also studied following chemotherapy. In the pretherapeutic setting, hydro-spiral CT identified gastric lymphoma in 8 patients, while a false negative result was seen in 6 patients. In addition, the localization of the lymphoma within the stomach was divergent between CT and endosonography in 1 patient. In the 2 patients who were also studied after therapy, CT showed unchanged thickening of the stomach wall in spite of normalization in the endosonographic assessment as well as the histologic evaluation.
  
  
  CONCLUSIONS
  Our results demonstrate the superiority of endosonography over hydro-spiral CT for the staging and follow-up of patients with gastric lymphoma, who should therefore be managed at centers where endosonography is available.
authors.affiliation: Department of Radiology, Internal Medicine, University of Vienna, Austria.
authors.forename: Friedrich
authors.initials: F
authors.lastname: Vorbeck
authors.forename: Christian
authors.initials: C
authors.lastname: Osterreicher
authors.forename: Andreas
authors.initials: A
authors.lastname: Püspök
authors.forename: Brigitte
authors.initials: B
authors.lastname: Dragosics
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Fiebiger
authors.forename: Andreas
authors.initials: A
authors.lastname: Chott
authors.forename: Markus
authors.initials: M
authors.lastname: Raderer
mesh_terms: D000328:Adult; D000368:Aged; D019160:Endosonography; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D013270:Stomach / Q000000981:diagnostic imaging / Q000473:pathology / Q000648:ultrastructure; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D036542:Tomography, Spiral Computed