title: Enantioselective Michael addition of beta-keto esters to methyl vinyl ketone employing a chiral N,N'-dioxide-scandium trifluoromethanesulfonate complex as a catalyst.
abstract: An enantioselective Michael addition of beta-keto esters to methyl vinyl ketone exploiting a chiral N,N'-dioxide-scandium trifluoromethanesulfonate complex as a catalyst affords the corresponding Michael adducts in high yields and with enantioselectivities of up to 80% ee.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. nakajima@pharm.hokudai.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Nakajima
authors.forename: Y
authors.initials: Y
authors.lastname: Yamaguchi
authors.forename: S
authors.initials: S
authors.lastname: Hashimoto