title: Platelet-derived growth factor A (pdgf-a) expression during zebrafish embryonic development.
abstract: Zebrafish pdgf-a gene was cloned and its expression pattern studied during zebrafish embryogenesis. Zebrafish pdgf-a mRNA was present at high levels in fertilized eggs as well as in all embryonic cells up to the end of gastrulation. Spatially restricted expression started after the onset of segmentation and was mainly localized in the developing pharyngeal arches. Transient expression was also detected in Kupffer's vesicle, a teleost-specific structure, and in lateral trunk and tail regions surrounding the neural keel, as well as areas of the developing pronephros.
authors.affiliation: Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, 119260.
authors.forename: Lihui
authors.initials: L
authors.lastname: Liu
authors.forename: Vladimir
authors.initials: V
authors.lastname: Korzh
authors.forename: Nararaja V
authors.initials: NV
authors.lastname: Balasubramaniyan
authors.forename: Marc
authors.initials: M
authors.lastname: Ekker
authors.forename: Rouwen
authors.initials: R
authors.lastname: Ge
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017124:Conserved Sequence; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D010982:Platelet-Derived Growth Factor / Q000737:chemistry / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D015027:Zebrafish / Q000196:embryology* / Q000235:genetics*
chemical_list: D010982:Platelet-Derived Growth Factor; D012333:RNA, Messenger; C075278:platelet-derived growth factor A