title: Effect of long-term aluminum feeding on lipid/phospholipid profiles of rat brain synaptic plasma membranes and microsomes.
abstract: Long-term exposure to AlCl_3 resulted in 57% phospholipid (TPL) content of synaptic plasma membranes from rat brain with significant decrease in the proportion and content of most of the phospholipid classes (32%- decreases was of lesser magnitude for phosphatidylcholine (PC) and phosphatidylethanolamine (PE). The microsomal TPL and cholesterol (CHL) content decreased by 74% composition. However, the contents of all phospholipids decreased uniformly by about 70%. fluidized in Al fed rats. The results suggest that long-term exposure of rats to Al can alter the structure/function of synaptic plasma membranes and microsomes.
authors.affiliation: Department of Biochemistry, Faculty of Science, M.S.University of Baroda, Vadodara 390 002, India.
authors.forename: Jignesh D.
authors.initials: JD
authors.lastname: Pandya
authors.forename: Kunjan R.
authors.initials: KR
authors.lastname: Dave
authors.forename: Surendra S.
authors.initials: SS
authors.lastname: Katyare