Treatment of an acromegalic cat with the dopamine agonist L-deprenyl.
Acromegaly was diagnosed in a 14-year-old domestic short hair cat presented for investigation and management of apparently insulin-resistant diabetes mellitus. Treatment with L-deprenyl and high doses of insulin was commenced. The L-deprenyl did not reduce the requirement for high doses of insulin and did not appear to reduce the clinical signs associated with the disease. The cat was euthanased one year after initial presentation.
Abraham
L A
LA
University of Melbourne Veterinary Clinic and Hospital, Werribee, Victoria.
Helmond
S E
SE
Mitten
R W
RW
Charles
J A
JA
Holloway
S A
SA
D000172:Acromegaly / Q000150:complications / Q000188:drug therapy / Q000662:veterinary*; D000239:Adenoma, Acidophil / Q000150:complications / Q000175:diagnosis / Q000662:veterinary; D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy* / Q000209:etiology; D002415:Cats; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary; D018491:Dopamine Agonists / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D017809:Fatal Outcome; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007333:Insulin Resistance; D049528:Insulin, Long-Acting / Q000627:therapeutic use; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis / Q000662:veterinary; D012642:Selegiline / Q000627:therapeutic use*
D018491:Dopamine Agonists; D007004:Hypoglycemic Agents; D049528:Insulin, Long-Acting; D012642:Selegiline