title: [Migration of CD4+ and CD8+ lymphocytes into the internal lining of tuberculous pleural empyema and tuberculous caverns during their local sanitation].
abstract: Cytological, immunological, and microbiological findings after sanitation of pulmonary caverns and pleural empyemas were analyzed in 13 patients: 7 with empyemas of residual pleural cavities after surgery for pulmonary tuberculosis and 6 with fibrocavernous pulmonary tuberculosis. It has been found that target sanitation of the intrapulmonary and intrapleural cavities enhances lymphocytic penetration into the internal part of the cavitary wall, infiltrating lymphocytes represent mainly CD4+ cells whose count progressively increases with successful sanitation, as appeared as a significant rise in both the so-called immunoregulatory index (CD4+/CD8+ ratios of 3.4 to 6.1). A study of the populational composition of lymphocytes promotes an objective evaluation of the magnitude of a specific tuberculous inflammatory process in the wall of the cavity of empyemas and caverns.
authors.forename: V N
authors.initials: VN
authors.lastname: Trusov
authors.forename: G A
authors.initials: GA
authors.lastname: Kosm iadi
authors.forename: G M
authors.initials: GM
authors.lastname: Nikolaeva
authors.forename: A A
authors.initials: AA
authors.lastname: Vorob'ev
authors.forename: T L
authors.initials: TL
authors.lastname: Tarasenko
mesh_terms: D001419:Bacteria / Q000302:isolation & purification; D015704:CD4 Antigens / Q000276:immunology*; D016516:CD4-CD8 Ratio; D016827:CD8 Antigens / Q000276:immunology*; D004654:Empyema, Tuberculous / Q000276:immunology / Q000382:microbiology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D011013:Pneumonectomy; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000276:immunology / Q000382:microbiology / Q000601:surgery / Q000628:therapy*
chemical_list: D015704:CD4 Antigens; D016827:CD8 Antigens