[Alzheimer's dementia or cerebral toxoplasmosis? Case study of dementia following toxoplasmosis infection].
Cerebral toxoplasmosis can lead to dementia in AIDS and in immunodeficient patients. We present a case study in which cerebral toxoplasmosis was associated with a dementia of Alzheimer type. Half a year to one year before the cognitive impairment began, the patient suffered a subacute infection of toxoplasmosis at the age of 56. Neuropsychological examination as well as MRI suggested a diagnosis of dementia with infectious genesis. However, serological tests showed only little evidence of infection. Since the results of the PET examination indicated changes in the glucose metabolism typical of Alzheimer's disease, we infer a comorbidity of cerebral toxoplasmosis and dementia of Alzheimer type.
Freidel
St
S
Gerontopsychiatrisches Zentrum Hegibach, Psychiatrische Universitätsklinik Zürich, Switzerland.
Martin-Sölch
Ch
Ch
Schreiter-Gasser
U
U
D000544:Alzheimer Disease / Q000175:diagnosis* / Q000276:immunology; D000913:Antibodies, Protozoan / Q000097:blood; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009483:Neuropsychological Tests; D011859:Radiography; D014055:Tomography, Emission-Computed; D016781:Toxoplasmosis, Cerebral / Q000175:diagnosis* / Q000276:immunology
D000913:Antibodies, Protozoan; D007070:Immunoglobulin A; D007074:Immunoglobulin G