[Microvessel count in normal cervical tissue and in cervical carcinomas].
This study was conducted to determine microvessel count(MVC) status in normal cervical tissue (NCT) and in cervical carcinomas (CCs). 15 cases of NCT and 80 cases of CCs were stained by immunohistochemical method for Factor VIII related antigen (F8RA). The results showed that the MVC in CCs was much higher than that in NCT and it was correlated with clinical stage, size of tumor and lymph node status (P < 0.05). Every time when MVC increased by 5 in number (LM x 200, field 0.739 mm2), the chance of lymph node metastasis increased by 1.61 times. There was no relationship between MVC and tumor grade. These suggested that MVC might be a useful early parameter in the diagnosis and prognosis of CCs.
Yin
R
R
Department of Obstetric and Gynecology, Second Affiliated Hospital, WCUMS, Chengdu 610041.
Peng
Z
Z
Yao
Y
Y
Cao
Z
Z
D002294:Carcinoma, Squamous Cell / Q000098:blood supply*; D002584:Cervix Uteri / Q000098:blood supply*; D005260:Female; D006801:Humans; D008833:Microcirculation / Q000473:pathology; D009389:Neovascularization, Pathologic; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000098:blood supply*