title: [Two cases of stage IV type 4 gastric cancer with good response to TS-1].
abstract: We report two patients with Type 4 gastric cancers having multiple lymph node metastasis and carcinomatosa which responded well to TS-1. After administration of TS-1 orally for two courses, both patients showed improved extension of the gastric wall and almost complete reduction of metastatic lymph nodes. In case 2, colonic stenosis due to peritonum carcinomatosa disappeared after chemotherapy with TS-1. Total gastrectomy was performed in both patients in accordance with their wishes. It was confirmed histopathologically that TS-1 was effective against the primary sites and lymph node metastasis. Both patients are well without recurrence and continue taking TS-1.
authors.affiliation: 3rd Dept. of Internal Medicine, Asahikawa Medical College.
authors.forename: Naomi
authors.initials: N
authors.lastname: Shibata
authors.forename: Jiro
authors.initials: J
authors.lastname: Watari
authors.forename: Tomonobu
authors.initials: T
authors.lastname: Satoh
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanabe
authors.forename: Mikihiro
authors.initials: M
authors.lastname: Fujiya
authors.forename: Atsumi
authors.initials: A
authors.lastname: Yasuda
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Saitoh
authors.forename: Kinichi
authors.initials: K
authors.lastname: Yokota
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kohgo
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Kino
authors.forename: Minoru
authors.initials: M
authors.lastname: Matsuda
authors.forename: Shinichi
authors.initials: S
authors.lastname: Kasai
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000627:therapeutic use*; D011300:Preoperative Care; D011725:Pyridines / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid