title: Construction and Physical Mapping of the 35 cM YAC Contigs for the Region of Xp11.2 - p21.3.
abstract: One hundred and fifty-one YACs were selected from three libraries with a series of STS and other DNA probes of the human X chromosome p11.2 - p21.3 region. The YAC contigs, spanning about 35cM in all and generally cover the whole region, were constructed based on the physical analysis of the positive clones. A total of seventy-seven DNA markers of this region were located and ordered on this map with an average 454 kb spacing, in which fifty-three were polymorphic markers with an average 0.6 cM genetic spacing. These results facilitate the search for novel genes and the sequence analysis of this region.
authors.affiliation: Institute of Genetics, Fudan University, Shanghai 200433, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wei
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Wu
authors.forename: Wei-Min
authors.initials: WM
authors.lastname: Miao
authors.forename: Ti
authors.initials: T
authors.lastname: Cai
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Wu
authors.forename: Yi-Bin
authors.initials: YB
authors.lastname: Kang
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Chai