Successful non-surgical treatment of brain abscess and necrotizing fasciitis caused by Bacillus cereus.
Musculoskeletal and central nervous system infections caused by Bacillus cereus are very rare. Only a few cases have been reported, whose clinical courses strongly suggested that surgical procedures combined with appropriate antimicrobial therapy are necessary to cure these infections. A 60-year-old man with severe neutropenia due to myelodysplastic syndrome, developing necrotizing fasciitis and brain abscess caused by Bacillus cereus is reported. Without performing any surgical procedures, the patient was successfully treated with systemic antimicrobial therapy combined with granulocyte colony stimulating factor, which contributed to the increase in the neutrophil count.
Mori
Takehiko
T
Department of Medicine, Keio University School of Medicine, Tokyo.
Tokuhira
Michihide
M
Takae
Yujiro
Y
Mori
Shigehisa
S
Suzuki
Hirosi
H
Abe
Toru
T
Takeuchi
Tsutomu
T
D000900:Anti-Bacterial Agents; D016863:Bacillaceae Infections / Q000150:complications* / Q000188:drug therapy*; D001409:Bacillus cereus / Q000472:pathogenicity; D001922:Brain Abscess / Q000150:complications* / Q000188:drug therapy*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D019115:Fasciitis, Necrotizing / Q000150:complications* / Q000188:drug therapy*; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications; D009503:Neutropenia / Q000150:complications / Q000188:drug therapy; D011994:Recombinant Proteins
D000900:Anti-Bacterial Agents; D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor