title: GC-mS analysis and anti-microbial activity of acidic fractions obtained from Paeonia peregrina and Paeonia tenuifolia roots.
abstract: Fourteen aromatic and 24 aliphatic acids were determined by GC-MS analysis of acidic fractions obtained from Paeonia peregrina and Paeonia tenuifolia roots. Benzoic acid and its monohydroxy-, dihydroxy- and trihydroxy-derivatives are the main acid components of both Paeonia species. Some fractions could serve as a source of benzoic, 4-hydroxybenzoic, vanillic and gallic acids, as well as of ethyl gallate. The fractions inhibited the growth of Staphylococcus aureus, Escherichia coli and Candida albicans.
authors.affiliation: Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia.
authors.forename: Antoaneta
authors.initials: A
authors.lastname: Ivanova
authors.forename: Ivajla
authors.initials: I
authors.lastname: Delcheva
authors.forename: Iva
authors.initials: I
authors.lastname: Tsvetkova
authors.forename: Atanas
authors.initials: A
authors.lastname: Kujumgiev
authors.forename: Ivanka
authors.initials: I
authors.lastname: Kostova
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification; D002176:Candida albicans / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects*; D008401:Gas Chromatography-Mass Spectrometry; D006868:Hydrolysis; D019684:Magnoliopsida / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010936:Plant Extracts