Respiratory syncytial virus infections in children and adults.
Respiratory syncytial virus is the leading cause of hospital admission for lower respiratory tract infection in young children and appears to be responsible for a significant burden of disease in adults, particularly the elderly and the immunocompromised. In this review, we describe the epidemiology, diagnosis and clinical manifestations of infection attributed to this virus. We also consider current therapeutic and prophylactic options and appraise strategies for vaccination that are in clinical trials.
Collins
C L
CL
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Level 4, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Pollard
A J
AJ
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D002986:Clinical Trials as Topic; D006801:Humans; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control; D022261:Respiratory Syncytial Virus Vaccines / Q000276:immunology; D018113:Respiratory Syncytial Virus, Human / Q000276:immunology
D000998:Antiviral Agents; D022261:Respiratory Syncytial Virus Vaccines