title: First thermally responsive supramolecular polymer based on glycosylated amino acid.
abstract: In materials science, a dynamic property sensitive to an environmental change (heat, light, electric current, pH, and other chemical or physical changes) is indispensable for intelligent materials. Such organic materials, however, are very limited even in conventional polymers. This paper clearly demonstrates that, regardless of the low molecular weight, a glycosylated amino acid derivative newly screened by a combinatorial method forms a macroscopic supramolecular hydrogel that reversibly swells or shrinks in response to the external temperature. Using the unique thermal response of the present hydrogel, we carried out the controlled release of DNA and the perfect removal of bisphenol A from the polluted water. Recently, advanced supramolecular polymers, in which monomers are noncovalently connected, are expected to be highly advantageous over traditional polymers because of their tunable and recyclable characteristics. The present result newly confers a dynamic feature on the supramolecular polymers, which is desirable for the sophisticated application in many fields.
authors.affiliation: PRESTO (Organization and Function, JST), Institute for Fundamental Research of Organic Chemistry (IFOC), and Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University, Fukuoka, 812-8581, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Kiyonaka
authors.forename: Kazunori
authors.initials: K
authors.lastname: Sugiyasu
authors.forename: Seiji
authors.initials: S
authors.lastname: Shinkai
authors.forename: Itaru
authors.initials: I
authors.lastname: Hamachi
mesh_terms: D000116:Acetylgalactosamine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry*; D004247:DNA / Q000737:chemistry; D006031:Glycosylation; D020100:Hydrogels / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000596:Amino Acids; D020100:Hydrogels; D004247:DNA; D000116:Acetylgalactosamine