title: Molecular control of neuronal migration.
abstract: Our understanding of neuronal migration has been advanced by multidisciplinary approaches. At the cellular level, tangential and radial modes of neuronal migration contribute to different populations of neurons and have differential dependence on glial cells. At the molecular level, extracellular guidance cues have been identified and intracellular signal transduction pathways are beginning to be revealed. Interestingly, mechanisms guiding axon projection and neuronal migration appear to be conserved with those for chemotactic leukocytes.
authors.affiliation: Department of Pediatrics, and Molecular Biology and Pharmacology, Box 8108, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA.
authors.forename: Hwan Tae
authors.initials: HT
authors.lastname: Park
authors.forename: Jane
authors.initials: J
authors.lastname: Wu
authors.forename: Yi
authors.initials: Y
authors.lastname: Rao
mesh_terms: D002465:Cell Movement; D002633:Chemotaxis; D007962:Leukocytes / Q000378:metabolism; D008954:Models, Biological; D008957:Models, Genetic; D009457:Neuroglia / Q000166:cytology*; D009474:Neurons / Q000166:cytology*; D015398:Signal Transduction; D020741:rho GTP-Binding Proteins / Q000378:metabolism
chemical_list: D020741:rho GTP-Binding Proteins