title: Directed and undirected asymmetric dihydroxylation reactions: application in the synthesis of a C-linked analogue of allolactose.
abstract: The complex OsO4.(S,S)-1,2-diphenyl-N,N'-bis(2,4,6-trimethylbenzyl)ethane-1,2-diamine is an effective reagent for the desymmetrisation of meso-1,2-bis(3,6-dihydro-2H-pyran-2-yl)ethanes by asymmetric dihydroxylation; this process, whose sense of diastereoselectivity depends on substitution and stereochemistry, has been exploited in the synthesis of a C-linked analogue of allolactose.
authors.affiliation: School of Chemistry, University of Leeds, Leeds, UK LS2 9JT.
authors.forename: R
authors.initials: R
authors.lastname: Hodgson
authors.forename: T
authors.initials: T
authors.lastname: Mahid
authors.forename: A
authors.initials: A
authors.lastname: Nelson