title: Precursor T-lymphoblastic leukemia with a novel t(1;22)(p34;q13).
abstract: A 37-year-old woman that presented with cervical lymphadenopathy and leukocytosis was found to have precursor T-lymphoblastic leukemia (T-ALL). Cytogenetic study of the leukemic cells showed a 46,XX, t(1;22)(p34;q13) karyotype. The t(1;22)(p34;q13) is a novel chromosomal abnormality in human malignancies and is probably a variant form of the t(1;14)(p34;q11) found in precursor T-ALL.
authors.affiliation: Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China. kfwong@ha.org.hk
authors.forename: K F
authors.initials: KF
authors.lastname: Wong
authors.forename: C C
authors.initials: CC
authors.lastname: So
authors.forename: G
authors.initials: G
authors.lastname: Lau
mesh_terms: D000328:Adult; D002878:Chromosomes, Human, Pair 1; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics*; D014178:Translocation, Genetic