Experimental supply-demand analysis of anaerobic yeast energy metabolism.
Experimental supply-demand analysis of yeast fermentative energy metabolism shows that control of the glycolytic flux is shared between supply and demand. In glucose limited chemostat cultures the supply block was modulated in a dilution rate change and demand block via a benzoic acid titration. Under these conditions the supply block had a flux control of 0.90 and the demand block a flux control of 0.10.
Kroukamp
O
O
Department of Biochemistry, University of Stellenbosch, South Africa. 9101705@sun.ac.za
Rohwer
J M
JM
Hofmeyr
J H S
JH
Snoep
J L
JL
D000244:Adenosine Diphosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism*; D000693:Anaerobiosis; D019817:Benzoic Acid / Q000378:metabolism; D004734:Energy Metabolism; D000431:Ethanol / Q000378:metabolism; D005285:Fermentation; D005947:Glucose / Q000378:metabolism; D006019:Glycolysis; D008433:Mathematics; D012441:Saccharomyces cerevisiae / Q000378:metabolism*
D000431:Ethanol; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D019817:Benzoic Acid; D005947:Glucose