The distribution and morphology of calbindin D28K- and calretinin-immunoreactive neurons in the visual cortex of mouse.
We studied the distribution and morphology of calbindin D28K- and calretinin-immunoreactive (IR) neurons in the mouse visual cortex with immunocytochemistry. Most of the calbindin D28K-IR neurons were located in layers II/III and V, while calretinin-IR neurons were predominantly located in layers II/III. The labeled neurons showed variations in morphology. The majority of the calbindin D28K-IR neurons were stellate and round or oval cells with multipolar dendrites. The majority of calretinin-IR neurons were vertical fusiform cells with long processes traveling perpendicular to the pial surface. In the mouse visual cortex, 20.2% of calbindin D28K-IR neurons contained calretinin and 27.2% of calretinin-IR neurons contained calbindin D28K. These results indicate that the calcium-binding proteins, calbindin D28K and calretinin are distributed in specific layers and in selective cell types of the mouse visual cortex.
Park
Hyun-Jung
HJ
Department of Biology, College of Natural Sciences, College of Agriculture, Kyungpook National University, Daegu, Korea.
Kong
Jee-Hyun
JH
Kang
Youn-Sil
YS
Park
Won-Mee
WM
Jeong
Seong-Ah
SA
Park
So-Min
SM
Lim
Jin-Kyu
JK
Jeon
Chang-Jin
CJ
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D064092:Calbindin 1; D064032:Calbindin 2; D064026:Calbindins; D005455:Fluorescent Antibody Technique; D051379:Mice; D009474:Neurons / Q000166:cytology / Q000276:immunology*; D064030:S100 Calcium Binding Protein G / Q000276:immunology*; D014793:Visual Cortex / Q000166:cytology / Q000276:immunology*
D000911:Antibodies, Monoclonal; C576499:Calb1 protein, mouse; C576511:Calb2 protein, mouse; D064092:Calbindin 1; D064032:Calbindin 2; D064026:Calbindins; D064030:S100 Calcium Binding Protein G