title: Influence of St. Jude medical valve in patients with aortic stenosis and small aortic annulus on cardiac function and late survival result.
abstract: This clinical study analyzes our experience of postoperative cardiac function and long-term survival rate in patients with aortic stenosis and small-size St. Jude Medical (SJM) valve. Sixty-eight patients who underwent aortic valve replacement by SJM valve were divided into two groups by preoperative aortic annulus diameter. Group 1 consisted of 44 patients with small aortic annulus and small-size SJM valve (19 mm or 21 mm). In Group 1, small SJM standard valves were implanted in 16 patients, and small SJM Hemodynamic Plus (HP) valves were implanted in 28 patients. Group 2 consisted of 24 patients with large-size SJM standard valve (23 mm or larger). Preoperative left ventricular mass index, left ventricular dimension, the dimension of ascending aorta, and body surface area were significantly smaller in Group 1 than in Group 2. Average age at surgery was older in Group 1 than in Group 2. Effective orifice area index of the SJM valve measured by the manufacturer's data was smaller in Group 1 than in Group 2. Postoperative left ventricular mass indexes of Group 1 (standard valve or HP valve) and Group 2 significantly decreased in comparison with the preoperative mass indexes. Postoperative left ventricular ejection fraction and the peak ejection rate of Group 1 were not different from those of Group 2. The 10 year survival rate of Group 1 was 79%, and the rate of Group 2 was 77%. At 10 years after surgery, freedom from valve-related complication of Group 1 was 80%, and freedom from complication of Group 2 was 81%. Our results demonstrated that small-size SJM valve afforded satisfactory long-term survival rate and valve-related event-free rate for elderly patients with small body surface area and small aortic annulus.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Saga Medical School, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Natsuaki
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Itoh
authors.forename: Yukio
authors.initials: Y
authors.lastname: Okazaki
authors.forename: Kyoumi
authors.initials: K
authors.lastname: Takarabe
authors.forename: Koujirou
authors.initials: K
authors.lastname: Furukawa
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Rikitake
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ohtubo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000401:mortality / Q000503:physiopathology* / Q000601:surgery*; D004452:Echocardiography; D005260:Female; D006334:Heart Function Tests; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011474:Prosthesis Design; D015996:Survival Rate; D013997:Time Factors