NMR reporter screening for the detection of high-affinity ligands.
Jahnke
Wolfgang
W
Novartis Pharma AG, P.O. Box, 4002 Basel, Switzerland. wolfgang.jahnke@pharma.novartis.com
Floersheim
Philipp
P
Ostermeier
Christian
C
Zhang
Xiaolu
X
Hemmig
Rene
R
Hurth
Konstanze
K
Uzunov
Doncho P
DP
D015096:3-Hydroxysteroid Dehydrogenases / Q000737:chemistry*; D045002:3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); D001572:Benzofurans / Q000737:chemistry*; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D011506:Proteins / Q000737:chemistry*
D001572:Benzofurans; D004791:Enzyme Inhibitors; D008024:Ligands; D011506:Proteins; C469295:2-acetylbenzofuran; D015096:3-Hydroxysteroid Dehydrogenases; D045002:3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)