title: Focal epithelial hyperplasia treated with interferon alpha-2a.
abstract: BACKGROUND
  Focal epithelial hyperplasia (FEH) is an uncommon benign oral condition that occurs mainly in young individuals of certain racial groups.
  
  
  METHODS
  A 21-year-old Caucasian man presented with FEH of the oral mucosa. The patient was treated with interferon alpha-2a three times a week for 14 weeks intramuscularly (a total of 162 million units).
  
  
  RESULTS
  At 2 months after the end of therapy, the papular lesions showed partial regression.
  
  
  CONCLUSIONS
  This treatment modality should be used in cases with diffuse focal epithelial hyperplasia.
authors.affiliation: Department of Dermatology, Gülhane Military Medical Academy, School of Medicine Etlik, Ankara, Turkey. okose@gata.edu.tr
authors.forename: O
authors.initials: O
authors.lastname: Köse
authors.forename: A
authors.initials: A
authors.lastname: Akar
authors.forename: M
authors.initials: M
authors.lastname: Safali
authors.forename: H B
authors.initials: HB
authors.lastname: Taştan
authors.forename: Z
authors.initials: Z
authors.lastname: Kurumlu
authors.forename: A R
authors.initials: AR
authors.lastname: Gür
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D017573:Focal Epithelial Hyperplasia / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D011994:Recombinant Proteins
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins