[Danazol: a new hormonal post-coital contraceptive method].
During a 9-month period, 84 female patients received post-coital contraception consisting either of an association of ethinyl estradiol/norgestrel or of danazol, in order to compare the safety and any adverse reaction of these 2 treatments.  Overall, the patients treated with danazol presented 1/3 as many side effects.  Nausea was reduced to 1/3 in frequency and vomiting to 1/9 in this group.  5 pregnancies were confirmed in the ethinyl estradiol/norgesterol group and 2 in the danazol group.  Although more cases are needed, it would appear that danazol is characterized by greater efficacy and patient acceptability.
Colombo
U
U
Zuliani
G
G
Molla
R
R
Santini
F
F
Santarone
M A
MA
Benzi
G
G
D001695:Biology; D003267:Contraception; D003270:Contraceptive Agents; D003271:Contraceptive Agents, Female; D003278:Contraceptives, Oral, Hormonal; D003281:Contraceptives, Postcoital; D004064:Digestive System; D004703:Endocrine System; D004997:Ethinyl Estradiol; D005193:Family Planning Services; D006728:Hormones; D009325:Nausea; D009644:Norgestrel; D010827:Physiology; D012816:Signs and Symptoms; D014839:Vomiting
D003270:Contraceptive Agents; D003271:Contraceptive Agents, Female; D003278:Contraceptives, Oral, Hormonal; D003281:Contraceptives, Postcoital; D006728:Hormones; D009644:Norgestrel; D004997:Ethinyl Estradiol
Biology; Contraception; Contraceptive Agents, Estrogen--side effects; Contraceptive Agents, Female--side effects; Contraceptive Agents, Postcoital--side effects; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--side effects; Endocrine System; Ethinyl Estradiol--side effects; Family Planning; Fertility Control, Postcoital--side effects; Gastrointestinal Effects; Hormones--side effects; Nausea; Norgestrel--side effects; Physiology; Signs And Symptoms; Vomiting