title: Molecular motors: force and movement generated by single myosin II molecules.
abstract: Muscle myosin II is an ATP-driven, actin-based molecular motor. Recent developments in optical tweezers technology have made it possible to study movement and force production on the single-molecule level and to find out how different myosin isoforms may have adapted to their specific physiological roles.
authors.affiliation: Department of Physiology and Pathophysiology, University of Heidelberg, INF 326, D-69126 Heidelberg, Germany.
authors.forename: Caspar
authors.initials: C
authors.lastname: Rüegg
authors.forename: Claudia
authors.initials: C
authors.lastname: Veigel
authors.forename: Justin E
authors.initials: JE
authors.lastname: Molloy
authors.forename: Stephan
authors.initials: S
authors.lastname: Schmitz
authors.forename: John C
authors.initials: JC
authors.lastname: Sparrow
authors.forename: Rainer H A
authors.initials: RH
authors.lastname: Fink
mesh_terms: D000255:Adenosine Triphosphate / Q000502:physiology; D000818:Animals; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000502:physiology; D009132:Muscles / Q000502:physiology*; D009218:Myosins / Q000737:chemistry / Q000502:physiology*
chemical_list: D000255:Adenosine Triphosphate; D009218:Myosins