Platelet function studies in women on oral contraceptive pills.
A study was conducted on a total of 100 women attending the Family Planning Clinic in Kuala Lumpur.  50 took combined low-dose estrogen and progesterone pills for a year or more and the other 50 used different methods of birth control.  Platelet aggregation, ATP release, Thromboxane B2, and 6-keto-prostaglandin F1alpha estimations were made to evaluate the effect of oral contraceptives (OCs) on platelet function and prostanoid production.  The results showed no significant differences in the parameters measured in the 2 groups investigated.  These findings are comparable to those reported by other studies, suggesting relatively low risk, if any, of thrombosis in OC users.
Ishak
R
R
Mohamed
A B
AB
Hassan
K
K
D001208:Asia; D001210:Asia, Southeastern; D001695:Biology; D001769:Blood; D019411:Clinical Laboratory Techniques; D003267:Contraception; D003276:Contraceptives, Oral; D003430:Cross-Sectional Studies; D003906:Developing Countries; D003933:Diagnosis; D004194:Disease; D004617:Embolism; D005193:Family Planning Services; D008296:Malaysia; D010827:Physiology; D010974:Platelet Aggregation; D012106:Research; D012107:Research Design; D012307:Risk Factors; D013923:Thromboembolism; D014652:Vascular Diseases
D003276:Contraceptives, Oral
Asia; Biology; Contraception; Contraceptive Methods--side effects; Control Groups; Cross Sectional Analysis; Developing Countries; Diseases; Embolism; Examinations And Diagnoses; Family Planning; Hematological Effects--changes; Hemic System; Laboratory Examinations And Diagnoses; Malaysia; Measurement; Oral Contraceptives--side effects; Physiology; Platelet Aggregation; Research Methodology; Risk Factors; Southeastern Asia; Thromboembolism; Vascular Diseases