title: Cholinergic control of heart rate by nitric oxide is site specific.
abstract: Parasympathetic control of heart rate involves the exocytotic release of acetylcholine and muscarinic receptor regulation of pacemaking currents. Endogenous nitric oxide can potentially regulate all of these processes; however, recent work suggests that the main functional role of nitric oxide lies in the modulation of acetylcholine release.
authors.affiliation: University Laboratory of Physiology, Oxford University, Oxford OX1 3PT, UK.
authors.forename: Neil
authors.initials: N
authors.lastname: Herring
authors.forename: Edward J F
authors.initials: EJ
authors.lastname: Danson
authors.forename: David J
authors.initials: DJ
authors.lastname: Paterson
mesh_terms: D000818:Animals; D001683:Biological Clocks; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000502:physiology; D052250:Nitric Oxide Synthase Type III; D010275:Parasympathetic Nervous System / Q000502:physiology*
chemical_list: D009569:Nitric Oxide; C496314:NOS3 protein, human; D019001:Nitric Oxide Synthase; D052250:Nitric Oxide Synthase Type III