title: Occurrence of bisphenol A in surface water and uptake in fish: evaluation of field measurements.
abstract: In this study the actual presence of the suspected endocrine disrupter Bisphenol A (BPA) in water systems was studied in the Netherlands. BPA was shown to be present in Dutch surface water at levels up to 330 ng/l, and one occasional observation of 21 microg/l. During the three sampling periods, 60-80% of the samples, most from marine and estuarine locations, contained BPA levels below the limit of quantification (14-40 ng/l). At a selected number of locations the presence of BPA in fish was studied, which showed that BPA varied from 2 to 75 ng/g in the liver and 1 to 11 ng/g in the muscle. Based on present measured concentrations in surface water and on literature derived toxicity data it was concluded that ecotoxicological effects nor estrogenic effects are likely to occur in the field situation.
authors.affiliation: Institute for Environmental Studies, Vrije Universiteit, Amsterdam, The Netherlands.
authors.forename: Angélique
authors.initials: A
authors.lastname: Belfroid
authors.forename: Martin
authors.initials: M
authors.lastname: van Velzen
authors.forename: Bert
authors.initials: B
authors.lastname: van der Horst
authors.forename: Dick
authors.initials: D
authors.lastname: Vethaak
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds; D002623:Chemistry Techniques, Analytical / Q000379:methods; D004968:Estrogens, Non-Steroidal / Q000032:analysis* / Q000378:metabolism; D005399:Fishes / Q000378:metabolism*; D005618:Fresh Water; D008099:Liver / Q000737:chemistry / Q000378:metabolism; D009132:Muscles / Q000737:chemistry / Q000378:metabolism; D009426:Netherlands; D009792:Oceans and Seas; D010636:Phenols / Q000032:analysis* / Q000493:pharmacokinetics; D018570:Risk Assessment; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000493:pharmacokinetics; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004968:Estrogens, Non-Steroidal; D010636:Phenols; D014874:Water Pollutants, Chemical; C006780:bisphenol A; D000098826:Bisphenol A Compounds