title: Perfusion MR imaging: clinical utility for the differential diagnosis of various brain tumors.
abstract: OBJECTIVE
  To determine the utility of perfusion MR imaging in the differential diagnosis of brain tumors.
  
  
  METHODS
  Fifty-seven patients with pathologically proven brain tumors (21 high-grade gliomas, 8 low-grade gliomas, 8 lymphomas, 6 hemangioblastomas, 7 metastases, and 7 various other tumors) were included in this study. Relative cerebral blood volume (rCBV) and time-to-peak (TTP) ratios were quantitatively analyzed and the rCBV grade of each tumor was also visually assessed on an rCBV map.
  
  
  RESULTS
  The highest rCBV ratios were seen in hemangioblastomas, followed by high-grade gliomas, metastases, low-grade gliomas, and lymphomas. There was no significant difference in TTP ratios between each tumor group (p<0.05). At visual assessment, rCBV was high in 17 (81%) of 21 high-grade gliomas and in 4 (50%) of 8 low-grade gliomas. Hemangioblastomas showed the highest rCBV and lymphomas the lowest.
  
  
  CONCLUSIONS
  Perfusion MR imaging may be helpful in the differentiation of thevarious solid tumors found in the brain, and in assessing the grade of the various glial tumors occurring there.
authors.affiliation: Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Sung Ki
authors.initials: SK
authors.lastname: Cho
authors.forename: Dong Gyu
authors.initials: DG
authors.lastname: Na
authors.forename: Jae Wook
authors.initials: JW
authors.lastname: Ryoo
authors.forename: Hong Gee
authors.initials: HG
authors.lastname: Roh
authors.forename: Chan Hong
authors.initials: CH
authors.lastname: Moon
authors.forename: Hong Sik
authors.initials: HS
authors.lastname: Byun
authors.forename: Jong Hyun
authors.initials: JH
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001810:Blood Volume / Q000502:physiology; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000556:secondary; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013997:Time Factors