title: Immunosuppressants.
abstract: This edition of the Med-Psych Drug-Drug Interactions Update begins a change in format. Starting with this column, each column will feature one drug-drug interaction (DDI) topic that will be explored in depth. This edition features DDIs associated with the commonly used immunosuppressants. These drugs are frequently encountered by consultation-liaison psychiatrists in tertiary care settings. Generally, most of these drugs have narrow safety and therapeutic windows; therefore, other drugs that change their serum levels can have deleterious effects. In this review, the DDI profiles of cyclosporine, tacrolimus, sirolimus, and the corticosteroids are explored.
authors.affiliation: Center for Geriatric Psychiatry, Tuality Forest Grove Hospital, Forest Grove, Ore., 97116, USA. scott.armstrong@tuality.org
authors.forename: Scott C
authors.initials: SC
authors.lastname: Armstrong
authors.forename: Kelly L
authors.initials: KL
authors.lastname: Cozza
authors.forename: Elisabeth A
authors.initials: EA
authors.lastname: Pimentel
mesh_terms: D006801:Humans; D007166:Immunosuppressive Agents / Q000145:classification* / Q000494:pharmacology*
chemical_list: D007166:Immunosuppressive Agents