Blocking oncogenes in malignant cells by RNA interference--new hope for a highly specific cancer treatment?
A little more than one year after the first demonstration that silencing of endogenous human genes is possible in cell culture, the new tool of RNA interference (RNAi) enters the field of tumor therapy.
Borkhardt
Arndt
A
Children's University Hospital Giessen, Pediatric Hematology and Oncology, Feulgenstr. 12, 35392, Giessen, Germany. arndt.borkhardt@paediat.med.uni-giessen.de
D000818:Animals; D011905:Genes, ras; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D034622:RNA Interference