Some metabolic and hormonal changes in women using long acting injectable contraceptives.
Some metabolic and hormonal changes in women using longacting injectables as a contraceptive method were examined.  The 2 main injectables utilized were depomedroxyprogesterone acetate (DMPA), given every 90 +or- 5 days, and norethisterone enanthate (NET/EN) injected every 60 +or- 5 days.  None of the studied cases became pregnant during injectable use, indicating the high contraceptive efficacy of the method.  No statistically significant changes were observed in hemoglobin, hematocrit, all protein fractions including albumin, alpha1, alpha2 beta, gamma immunoglobulins IgG, IgA, and IgM after 6 and 12 months in both groups of injectable users as compared with the preinjection values.  Statistically significant suppression of the estimated hormones, Follitropin, Luteotropin, and Estradiol-17beta were detected in both groups of NET/EN and DMPA users, after 6 and 12 months, as compared with the preinjection values.
Abdel-sayed
W S
WS
Toppozada
H K
HK
Said
S A
SA
El-sayed
O K
OK
D000349:Africa; D000352:Africa, Northern; D001695:Biology; D001769:Blood; D003267:Contraception; D003270:Contraceptive Agents; D003271:Contraceptive Agents, Female; D003625:Data Collection; D003906:Developing Countries; D004534:Egypt; D004703:Endocrine System; D004958:Estradiol; D004967:Estrogens; D005069:Evaluation Studies as Topic; D005193:Family Planning Services; D005640:Follicle Stimulating Hormone; D006062:Gonadotropins; D006065:Gonadotropins, Pituitary; D006728:Hormones; D007267:Injections; D007986:Luteinizing Hormone; D017258:Medroxyprogesterone Acetate; D008660:Metabolism; D008877:Middle East; D009640:Norethindrone; D010827:Physiology; D012106:Research; D013256:Steroids
D003270:Contraceptive Agents; D003271:Contraceptive Agents, Female; D004967:Estrogens; D006062:Gonadotropins; D006065:Gonadotropins, Pituitary; D006728:Hormones; D013256:Steroids; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D017258:Medroxyprogesterone Acetate; D009640:Norethindrone
Africa; Arab Countries; Biology; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods; Data Collection; Developing Countries; Egypt; Endocrine System; Estradiol--analysis; Estrogens; Evaluation; Family Planning; Follicle Stimulating Hormone--analysis; Gonadotropins; Gonadotropins, Pituitary; Hematological Effects; Hemic System--analysis; Hormones; Injectables; Luteinizing Hormone--analysis; Mediterranean Countries; Medroxyprogesterone Acetate; Metabolic Effects; Norethindrone; Norethindrone Acetate; Northern Africa; Physiology; Research Methodology; Steroid Metabolic Effects