A comparison of osmotic dilators, Lamicel and Dilapan, and a prostaglandin E1 analogue, gemeprost, for ripening the cervix before legal abortion.
66 primigravid women were allocated at random to receive either intravaginal application of the prostaglandin El analogue, gemeprost, or intracervical insertion of 1 of 2 osmotic dilators, Lamicel or Dilapan, 3 hours before legal abortion at 7-14 weeks gestation.  Insertion of the dilators was not possible in 5 patients.  All 3 methods were otherwise equally effective in achieving cervical dilatation and there was no difference in the need for or resistance to further dilatation between the 3 groups.  Gemeprost was the most easily administered, and would be the most appropriate for routine preoperative use.
Golland
I M
IM
Vaughan-williams
C A
CA
Elstein
M
M
D000028:Abortion, Induced; D001695:Biology; D001723:Birth Rate; D002584:Cervix Uteri; D003267:Contraception; D003268:Contraception Behavior; D003710:Demography; D004703:Endocrine System; D005069:Evaluation Studies as Topic; D005193:Family Planning Services; D005298:Fertility; D005835:Genitalia; D005836:Genitalia, Female; D006801:Humans; D010298:Parity; D010342:Patient Acceptance of Health Care; D010827:Physiology; D011153:Population; D011157:Population Dynamics; D011453:Prostaglandins; D012106:Research; D013223:Statistics as Topic; D014566:Urogenital System; D014599:Uterus
D011453:Prostaglandins
Abortion, Induced; Biology; Cervical Effects; Cervix; Contraception; Contraceptive Usage; Data Analysis; Demographic Factors; Endocrine System; Evaluation; Family Planning; Fertility; Fertility Control, Postconception; Fertility Measurements; Genitalia; Genitalia, Female; Method Acceptability; Parity; Physiology; Population; Population Dynamics; Primiparity; Prostaglandins--administraction and dosage; Research Methodology; Urogenital System; Uterus