title: Superior vena cava syndrome after bone marrow transplantation caused by aspergillosis: a case report.
abstract: Aspergillosis is known for the variety of unusual presentations in immuno-suppressed patients. We report a patient in whom aspergillosis caused the superior vena cava (SVC) syndrome. A 37-year-old woman became febrile soon after bone marrow transplantation (BMT). Chest radiography demonstrated a 5-cm mass extending from the right lung apex to the right supraclavicular fossa beside her Hickman catheter. She then developed SVC syndrome, which progressed despite treatment. Despite recovery of the white blood cell count, the patient continued to deteriorate, became comatose, suffered a cardiac arrest and died 31 days after BMT. Autopsy revealed Aspergillus infection at the apex of the right lung associated with innominate artery thrombosis.
authors.affiliation: Second Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Takatsuka
authors.forename: T
authors.initials: T
authors.lastname: Wakae
authors.forename: A
authors.initials: A
authors.lastname: Mori
authors.forename: M
authors.initials: M
authors.lastname: Okada
authors.forename: Y
authors.initials: Y
authors.lastname: Fujimori
authors.forename: Y
authors.initials: Y
authors.lastname: Takemoto
authors.forename: T
authors.initials: T
authors.lastname: Okamoto
authors.forename: A
authors.initials: A
authors.lastname: Sugihara
authors.forename: N
authors.initials: N
authors.lastname: Terada
authors.forename: A
authors.initials: A
authors.lastname: Kanamaru
authors.forename: E
authors.initials: E
authors.lastname: Kakishita
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000150:complications* / Q000209:etiology; D001344:Autopsy; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007938:Leukemia / Q000150:complications / Q000628:therapy; D013479:Superior Vena Cava Syndrome / Q000209:etiology / Q000382:microbiology*; D014184:Transplantation, Homologous