title: [Methods of determination of fluoxetine nad fluvoxamine].
abstract: Two selective serotonin reuptake inhibitors (SSRIs) have been introduced: fluoxetine and fluvoxamine. The literature review shows most methods allow quantitative determination of SSRIs pharmaceutical preparations and plasma, in the lower ng/ml range and that they are, therefore, suitable for therapeutic drug monitoring purposes of this category of drugs. Most procedures are based on investigation of this drugs by spectrophotometric, electrochemical and chromatographic procedures with detection by various detectors.
authors.affiliation: Zakładu Chemii Ogólnej i Nieorganicznej Uniwersytetu w Białymstoku.
authors.forename: Barbara
authors.initials: B
authors.lastname: Starczewska
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Mielech
authors.forename: Ewa
authors.initials: E
authors.lastname: Kleszczewska
mesh_terms: D018687:Antidepressive Agents, Second-Generation; D016903:Drug Monitoring / Q000379:methods*; D005473:Fluoxetine / Q000097:blood / Q000737:chemistry / Q000378:metabolism; D016666:Fluvoxamine / Q000097:blood / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017367:Selective Serotonin Reuptake Inhibitors / Q000097:blood / Q000737:chemistry / Q000378:metabolism
chemical_list: D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine; D016666:Fluvoxamine; D017367:Selective Serotonin Reuptake Inhibitors