title: Assembly of polyamines via amino acids from three components using cobalt(III) template methodology.
abstract: A versatile and efficient template synthesis has been developed to synthesise novel polyamines [e.g. rac-N3-(3-aminopropyl)butane-1,3-diamine, isospermidine 1] via amino acids [e.g. (2R,4S/2S,4R)-N4-(3-aminopropyl)-2,4-diaminopentanoic acid] using cobalt(III) to assemble the three precursor components in a biomimetic manner.
authors.affiliation: Department of Chemistry, Bedson Building, University of Newcastle upon Tyne, Newcastle upon Tyne, UK NE1 7RU.
authors.forename: Gilles
authors.initials: G
authors.lastname: Laval
authors.forename: William
authors.initials: W
authors.lastname: Clegg
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Crane
authors.forename: Anders
authors.initials: A
authors.lastname: Hammershøi
authors.forename: Alan M
authors.initials: AM
authors.lastname: Sargeson
authors.forename: Bernard T
authors.initials: BT
authors.lastname: Golding
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D003035:Cobalt / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D011073:Polyamines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000596:Amino Acids; D011073:Polyamines; D003035:Cobalt