title: [Pharmacodynamic effects and clinical effectiveness of a combination of herbal substances comprised of Cone Flower, Wild Indigo and White Cedar].
abstract: The effect of the single active ingredients Echinaceae (purpureae et pallidae) radix, Baptisiae tinctoriae radix and Thujae occidentalis herba as well as of the combination Esberitox N has been verified in vitro, in vivo, in animal experiments and in human pharmacology (5). The pharmaceutical has immunomodulating and antiviral characteristics, whereby the immune system is probably influenced unspecifically, especially by increasing the macrophage activity. The efficacy for viral respiratory tract infections has been proven yet again in recent GCP-compliant, clinical studies (15, 17). Under the influence of the phytotherapeutic the duration of the illness decreased with a responder rate that was significantly higher than under placebo. The therapeutic benefit was even more pronounced, if the pharmaceutical was applied as early as possible. It has a high drug safety.
authors.affiliation: Medizinischen Forschung von Schaper & Brümmer GmbH & Co. KG, Bahnhofstrasse 35, D-38259 Salzgitter, Deutschland. gert.koehler@schaper-bruemmer.de
authors.forename: G
authors.initials: G
authors.lastname: Köhler
authors.forename: C
authors.initials: C
authors.lastname: Bodinet
authors.forename: J
authors.initials: J
authors.lastname: Freudenstein
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects / Q000627:therapeutic use*; D000818:Animals; D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D029779:Cupressaceae; D004338:Drug Combinations; D020900:Echinacea; D006801:Humans; D019684:Magnoliopsida; D008517:Phytotherapy; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000276:Adjuvants, Immunologic; D000998:Antiviral Agents; D004338:Drug Combinations; D010936:Plant Extracts