Hypoplasia of the corpus callosum and obsessive-compulsive symptoms.
Abnormalities in the corpus callosum, which connects the cerebral hemispheres, have been implicated in the pathogenesis of obsessive-compulsive disorder. This is a report of two cases of obsessive-compulsive disorder associated with hypoplasia of the corpus callosum. These data provide further support for corpus callosum-mediated dysfunction in obsessive-compulsive disorder.
Farchione
Tiffany R
TR
Department of Psychiatry, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.
Lorch
Elisa
E
Rosenberg
David R
DR
D000293:Adolescent; D000328:Adult; D061085:Agenesis of Corpus Callosum; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000209:etiology*