[Influence of Ginkgo biloba L. exocarp polysaccharides on serum superoxide dismutase activity and malondialdehyde level in mice under different states].
OBJECTIVE
To study the influence of Ginkgo biloba exocarp polysaccharides(GBEP) on serum superoxide dismutase(SOD) activity and malondialdehyde(MDA) level in mice under different states.


METHODS
GBEP was orally administrated to S180 bearing mice, cyclophosphamide(CTX) intoxicated mice and normal mice. The contents of SOD and MDA in the mice's blood were checked.


RESULTS
GBEP significantly enhanced SOD activity and decreased MDA content in S180 bearing mice. Similar effects were observed in CTX-intoxicated mice. In normal mice, however, no such effects were observed.


CONCLUSIONS
GBEP may modulate the free radical system in mice under abnormal states.
Xu
A
A
Medical College of Yangzhou University, Yangzhou 225002.
Chen
H
H
Wang
L
L
Wang
Q
Q
D000818:Animals; D005260:Female; D005638:Fruit / Q000737:chemistry; D020441:Ginkgo biloba / Q000737:chemistry*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism*; D051379:Mice; D008813:Mice, Inbred ICR; D009368:Neoplasm Transplantation; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D011897:Random Allocation; D012510:Sarcoma 180 / Q000378:metabolism* / Q000473:pathology; D012867:Skin / Q000737:chemistry; D013482:Superoxide Dismutase / Q000378:metabolism*; D014407:Tumor Cells, Cultured
D011134:Polysaccharides; D008315:Malondialdehyde; D013482:Superoxide Dismutase