Incidence of pre-eclampsia in first full-term pregnancies preceded by abortion.
The incidence of preeclampsia in 1st term pregnancies was studied in relation to whether or not they were preceded by pregnancies which ended in abortion--spontaneous or induced.  220 patients with previous abortion were studied along with 2 sets of controls, 1 with no previous abortion or pregnancy and 1 with a 2nd term pregnancy.  The incidence of preeclampsia was significantly lower than there had been a previous induced abortion but this was not as low as in cases with a 2nd term pregnancy.  This finding may be interpreted as supporting the idea that pregnancy exerts a protective effect against the risk of preeclampsia which may have an immunological basis.  A mechanism is suggested to explain the apparent "protective" effect of 1st pregnancies.
Beck
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D000028:Abortion, Induced; D001519:Behavior; D001695:Biology; D003710:Demography; D004194:Disease; D005193:Family Planning Services; D005298:Fertility; D007109:Immunity; D007155:Immunologic Factors; D015994:Incidence; D010827:Physiology; D011153:Population; D011157:Population Dynamics; D011248:Pregnancy Complications; D012106:Research; D012107:Research Design; D012725:Sexual Behavior; D013223:Statistics as Topic; D013995:Time; D013997:Time Factors
D007155:Immunologic Factors
Abortion History; Abortion, Induced; Behavior; Biology; Data Analysis; Demographic Factors; Diseases; Family Planning; Fertility; Fertility Control, Postconception; Immunity; Immunologic Factors; Incidence; Longterm Effects; Measurement; Physiology; Population; Population Dynamics; Pregnancy Complications; Reproductive Behavior; Research Methodology; Time Factors