Molecular motors: force and movement generated by single myosin II molecules.
Muscle myosin II is an ATP-driven, actin-based molecular motor. Recent developments in optical tweezers technology have made it possible to study movement and force production on the single-molecule level and to find out how different myosin isoforms may have adapted to their specific physiological roles.
Rüegg
Caspar
C
Department of Physiology and Pathophysiology, University of Heidelberg, INF 326, D-69126 Heidelberg, Germany.
Veigel
Claudia
C
Molloy
Justin E
JE
Schmitz
Stephan
S
Sparrow
John C
JC
Fink
Rainer H A
RH
D000255:Adenosine Triphosphate / Q000502:physiology; D000818:Animals; D006801:Humans; D009119:Muscle Contraction / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000502:physiology; D009132:Muscles / Q000502:physiology*; D009218:Myosins / Q000737:chemistry / Q000502:physiology*
D000255:Adenosine Triphosphate; D009218:Myosins