New insights into the role of cortisol and the glucocorticoid receptor in severe depression.
Gold
Philip W
PW
National Institutes of Health, National Institute of Mental Health, Clinical Neuroendocrinology Branch, Intramural Research Program, 20852, Bethesda, MD, USA
Drevets
Wayne C
WC
Charney
Dennis S
DS
D000679:Amygdala / Q000378:metabolism / Q000503:physiopathology; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy / Q000378:metabolism* / Q000503:physiopathology; D006624:Hippocampus / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism / Q000503:physiopathology; D015735:Mifepristone / Q000494:pharmacology / Q000627:therapeutic use; D017397:Prefrontal Cortex / Q000378:metabolism / Q000503:physiopathology; D011965:Receptors, Glucocorticoid / Q000378:metabolism*
D000928:Antidepressive Agents; D011965:Receptors, Glucocorticoid; D015735:Mifepristone; D006854:Hydrocortisone