title: Water-induced pruritus in haematologically controlled polycythaemia vera: response to phototherapy.
abstract: BACKGROUND
  Water-induced pruritus is characterized by the development of intense and widespread itching after contact with water at any temperature and without observable skin lesions. Around 40-52% of patients with polycythaemia vera (PV) have water-induced pruritus, and more than 20% of the patients continue with symptoms despite an adequate control of the underlying disease. The aetiology is unknown and treatment is often unsuccessful. We report a patient with a haematologically controlled polycythaemia vera and water-induced pruritus that responded to phototherapy.
  
  
  METHODS
  An 83-year-old woman with haematologically controlled PV referred with intense water-induced pruritus without cutaneous lesions. Topical emollients and oral antihistamines were unsatisfactory and so phototherapy treatment (90% UVA/10% UVB) three times a week was commenced.
  
  
  RESULTS
  Improvement was visible after 1 month and at the end of 3 months the pruritus had disappeared and treatment was stopped.
  
  
  CONCLUSIONS
  It is considered that the successful treatment in this patient is due to the UVB radiation.
authors.affiliation: Department of Dermatology, Hospital Universitario de la Princesa, Madrid, Spain. agarciad@meditex.es
authors.forename: A
authors.initials: A
authors.lastname: Hernández-Núñez
authors.forename: E
authors.initials: E
authors.lastname: Daudén
authors.forename: S
authors.initials: S
authors.lastname: Córdoba
authors.forename: M
authors.initials: M
authors.lastname: Aragüés
authors.forename: A
authors.initials: A
authors.lastname: García-Díez
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D011087:Polycythemia Vera / Q000503:physiopathology* / Q000628:therapy; D011537:Pruritus / Q000209:etiology / Q000628:therapy*; D014467:Ultraviolet Therapy; D014867:Water / Q000009:adverse effects*
chemical_list: D014867:Water