title: An open trial of topical tacrolimus for erosive oral lichen planus.
abstract: Erosive oral lichen planus is a chronic, painful disease that is frequently refractory to treatment. We describe 6 patients with erosive oral lichen planus, not responsive to topical steroids, who showed substantial improvement with the use of topical tacrolimus ointment 0.1%. This medication was well tolerated and appears to be effective in controlling erosive oral lichen planus.
authors.affiliation: Department of Dermatology, Oregon Health and Science University, Portland 97201, USA.
authors.forename: Lynne
authors.initials: L
authors.lastname: Morrison
authors.forename: F James
authors.initials: FJ
authors.lastname: Kratochvil
authors.forename: Annalisa
authors.initials: A
authors.lastname: Gorman
mesh_terms: D000287:Administration, Topical; D000328:Adult; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D017676:Lichen Planus, Oral / Q000097:blood / Q000188:drug therapy*; D008297:Male; D016559:Tacrolimus / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus