title: Quality of life in patients with aggressive non-Hodgkin's lymphoma. Validation of the medical outcomes study short form 20 and the Rotterdam symptom checklist in older patients.
abstract: In the elderly population, cancer treatment aims to cure and/or maintain Quality of Life (QoL). However, there is little QoL data to provide evidence for QoL benefits for some of the cancer treatments. This pilot study developed valid QoL questionnaires in French, for patients over 65 years with a diagnosis of large cell lymphoma, part of the Lymâge phase II study. They were asked to complete two questionnaires, the Medical Outcomes Study Short Form 20 (MOS SF20; generic) and the Rotterdam symptom checklist (RSCL; cancer-specific). Between June 1995 and April 1997, questionnaires were returned by 63 of 89 patients. This article reports the process undertaken to adapt the English version to a French setting, and provides the results of factor analysis, convergent and discriminant validity and reliability. Our data suggest that QoL questionnaires can be used in elderly patients. These two questionnaires are validated in French and would help us to analyse the QoL of elderly patients with the development of new treatments as done in the Lymâge study.
authors.affiliation: Regional Cancer Center, Institut Bergonié 229, cours de l'Argonne, 33076 Bordeaux Cedex, France. tchen@bergonie.org
authors.forename: Nadine
authors.initials: N
authors.lastname: Tchen
authors.forename: Pierre
authors.initials: P
authors.lastname: Soubeyran
authors.forename: Houchingue
authors.initials: H
authors.lastname: Eghbali
authors.forename: Joël
authors.initials: J
authors.lastname: Ceccaldi
authors.forename: Laurent
authors.initials: L
authors.lastname: Cany
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Balzon
authors.forename: Philippe
authors.initials: P
authors.lastname: Remuzon
authors.forename: Maxime
authors.initials: M
authors.lastname: Malet
authors.forename: Françoise
authors.initials: F
authors.lastname: Bonichon
authors.forename: Véronique
authors.initials: V
authors.lastname: Picot
authors.forename: Alain
authors.initials: A
authors.lastname: Monnereau
authors.forename: Bernard
authors.initials: B
authors.lastname: Hoerni
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000704:Analysis of Variance; D015577:Geriatric Assessment / Q000379:methods; D006801:Humans; D007802:Language; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis*; D011788:Quality of Life; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires / Q000592:standards*; D016896:Treatment Outcome