title: Graft subsidence after instrument-assisted anterior cervical fusion.
abstract: OBJECTIVE
  Bone grafts used in anterior cervical fusion (ACF) may subside postoperatively. The authors reviewed a recent series in which instrument-assisted ACF was performed to determine the degree of subsidence with respect to fusion length, use of segmental screws, and patient smoking status, age, and sex.
  
  
  METHODS
  Charts and implant records were reviewed for all 70 patients who underwent instrument-assisted ACF during a 2-year period. The procedures, grafting materials, plate types/lengths, and patient smoking status were recorded. The immediate postoperative and follow-up lateral radiographs were analyzed. The plate lengths and lengths of the fused segments were measured in a standardized fashion. The mean intraoperative and follow-up fusion segment lengths were 54.3 and 51.9 mm, respectively. Greater subsidence occurred in multilevel fusions than in single-level fusions. There were noticeable changes in the position of plates or screws on 14 of 70 follow-up x-ray films. No new neurological deficits related to graft subsidence occurred, and the reoperation rate was 3%. There was no statistical relation between subsidence and the following variables: segmental fixation, smoking status, sex, age, or dowel size when corrected for length of the plate. Hardware migration correlated significantly with plate length in cases of two- and three-level fusions.
  
  
  CONCLUSIONS
  The length of a fusion segment decreases in the immediate weeks following instrument-assisted ACF. Construct length is the most important determinant of subsidence. When designing multilevel cervical constructs, consideration of the effects of graft subsidence may help to avoid hardware-related complications.
authors.affiliation: Division of Neurosurgery, Virginia Commonwealth University Health Systems, Richmond, USA.
authors.forename: Gary W
authors.initials: GW
authors.lastname: Tye
authors.forename: R Scott
authors.initials: RS
authors.lastname: Graham
authors.forename: William C
authors.initials: WC
authors.lastname: Broaddus
authors.forename: Harold F
authors.initials: HF
authors.lastname: Young
mesh_terms: D000328:Adult; D000368:Aged; D001860:Bone Plates; D001863:Bone Screws; D016025:Bone Transplantation / Q000295:instrumentation*; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000601:surgery*; D004867:Equipment Design; D004868:Equipment Failure; D005260:Female; D006085:Graft Survival / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging* / Q000601:surgery; D011859:Radiography; D012086:Reoperation; D012907:Smoking / Q000009:adverse effects; D013123:Spinal Fusion / Q000295:instrumentation*; D013128:Spinal Osteophytosis / Q000000981:diagnostic imaging / Q000601:surgery*; D016474:Weight-Bearing / Q000502:physiology