Guillain-Barré syndrome.
Guillain-Barré syndrome is the most common paralytic illness affecting children and adolescents in countries with established immunization programs. The term is currently used to encompass a group of disorders in which an autoimmune response occurs days or weeks after an antecedent infection or event (e.g., immunization) and results in an acute polyradiculoneuropathy with flaccid weakness, areflexia, and increased cerebrospinal fluid protein. This chapter reviews the epidemiology, clinical presentation, diagnostic criteria, pathogenesis, treatment, and outcome of this condition.
Joseph
S Anne
SA
The Ohio State University Columbus Children's Hospital, Columbus, Ohio 43205, USA.
Tsao
Chang-Yong
CY
D000293:Adolescent; D000328:Adult; D002648:Child; D018450:Disease Progression; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D011379:Prognosis