Catalytic asymmetric carbon-carbon bond-forming reactions in aqueous media.
Use of water as a reaction solvent or co-solvent has received much attention in synthetic organic chemistry. Recently, successful examples of catalytic asymmetric carbon-carbon bond formation in aqueous media have been developed. Most of these examples show characteristic features that are realized only in the presence of water. The role of water in these reactions is also discussed here.
Manabe
Kei
K
Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo Bunkyo-ku, Tokyo 113-0033, Japan.
Kobayashi
Shū
S