[Preliminary studies on pharmacological actions of tongca and xiao-tongcao polysaccharides].
OBJECTIVE
To study and compare the immunologic function and antioxidative effect of Tongcao(Tongtuomu) and Xiao-Tongcao(Ximashanjingjiehua, Xinanxiuqiu, Ditanghua) polysaccharides.


METHODS
Mice were abdominally administrated with four kinds of polysaccharides at dosages of 80 mg/kg and 40 mg/kg for 7-10 days.


RESULTS
Four kinds of polysaccharides could increase the serum-lysozyme activity, phagocytic function of MPS and the serum hemolysin-antibody level in mice, inhibit the delayed hypersensitivity induced by DNCB in mice and raise the serum-catalase activity in mice.


CONCLUSIONS
Four kinds of Tongcao or Xiao-Tongcao polysaccharides have immunoregulative function and antioxidative effect. The results could enrich the contents of "A Study on Species-Sorting and Quality of Tongcao-Xiao-Tongcao Crude Drugs".
Shen
Y
Y
Chengdu University of TCM, Chengdu 610075.
Zeng
N
N
Liu
J
J
Jia
M
M
Zhang
Y
Y
Wei
Y
Y
Ma
Y
Y
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002374:Catalase / Q000097:blood; D004137:Dinitrochlorobenzene; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology*; D005260:Female; D031966:Hydrangea / Q000737:chemistry; D006968:Hypersensitivity, Delayed / Q000209:etiology / Q000517:prevention & control; D008264:Macrophages / Q000502:physiology; D019684:Magnoliopsida / Q000737:chemistry; D008297:Male; D051379:Mice; D009113:Muramidase / Q000097:blood; D010587:Phagocytosis / Q000187:drug effects; D010946:Plants, Medicinal / Q000737:chemistry*; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D011897:Random Allocation; D019685:Rosales / Q000737:chemistry
D000276:Adjuvants, Immunologic; D000975:Antioxidants; D004137:Dinitrochlorobenzene; D004365:Drugs, Chinese Herbal; D011134:Polysaccharides; D002374:Catalase; D009113:Muramidase