Clinical trial of a long-acting injectable contraceptive: NET-EN.
Injectable progestogen, norethisterone enanthate (NET-EN, 200 mg/ml) was administered to 122 women at 2 month intervals for more than 1 year.  Only a minority of women had consistently normal cycles.  Most women experienced some menstrual irregularities:  57% of users experienced irregular bleeding, 32% developed amenorrhea, while only 11% showed regular cyclic bleeding.  Important nonmenstrual side effects were weakness and abdominal pain.  No appreciable changes in body weight and blood pressure were recorded.
Chaudhuri
C
C
Mukherjea
M
M
D000568:Amenorrhea; D001794:Blood Pressure; D001835:Body Weight; D003267:Contraception; D003268:Contraception Behavior; D003270:Contraceptive Agents; D003271:Contraceptive Agents, Female; D004194:Disease; D005193:Family Planning Services; D006470:Hemorrhage; D007267:Injections; D008598:Menstruation; D008599:Menstruation Disturbances; D009640:Norethindrone; D010146:Pain; D010342:Patient Acceptance of Health Care; D012098:Reproduction; D012102:Reproductive Control Agents; D012106:Research
D003270:Contraceptive Agents; D003271:Contraceptive Agents, Female; D012102:Reproductive Control Agents; D009640:Norethindrone
Amenorrhea; Bleeding; Blood Pressure; Body Weight; Clinical Research; Contraception; Contraception Termination; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin--administraction and dosage; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--administraction and dosage; Contraceptive Agents--side effects; Contraceptive Methods; Contraceptive Usage; Diseases; Family Planning; Injectables; Menstruation; Menstruation Disorders; Method Acceptability; Norethindrone Enanthate--administraction and dosage; Norethindrone Enanthate--side effects; Norethindrone--administraction and dosage; Norethindrone--side effects; Pain; Reproduction; Reproductive Control Agents; Research Methodology