The synapse assembly model.
A framework for quantitative analysis of the mechanisms underlying immunological synapse assembly has been recently developed. This model uses partial differential equations to describe the binding interactions of receptors and ligands, with the constraint that they are embedded in apposed deformable membranes linked to a cytoskeletal complex.
Lee
Sung-Joo E
SJ
Biophysics Graduate Group, Dept of Chemistry, University of California, Berkeley, CA, USA.
Hori
Yuko
Y
Groves
Jay T
JT
Dustin
Michael L
ML
Chakraborty
Arup K
AK
D000818:Animals; D006801:Humans; D007365:Intercellular Junctions / Q000276:immunology*; D007700:Kinetics; D008024:Ligands; D008433:Mathematics; D018448:Models, Immunological; D011971:Receptors, Immunologic / Q000378:metabolism
D008024:Ligands; D011971:Receptors, Immunologic