title: Lewis Acid mediated reactions of zirconacyclopentadienes with aldehydes: one-pot synthetic route to indene and cyclopentadiene derivatives from aldehydes and benzyne or alkynes.
abstract: One-pot procedures for the preparation of highly substituted indenes, tetrahydroindenes, and cyclopentadienes have been developed by using a combination of zirconocene-mediated Cbond;C-bond-forming reactions with Lewis acid mediated activation of carbonyl groups. The carbonyl groups of aldehydes were deoxygenated in the reaction and behaved formally as a one-carbon unit. A variety of Lewis acids were checked and showed different reactivities in this reaction.
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education College of Chemistry and Molecular Engineering Peking University, Beijing 100871, China.
authors.forename: Changjia
authors.initials: C
authors.lastname: Zhao
authors.forename: Pixu
authors.initials: P
authors.lastname: Li
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Cao
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Xi