Effects of norandrostenedione and norandrostenediol in resistance-trained men.
The purpose of this study was to determine the effects of norsteroid supplementation (224 mg of 19-nor-4-androstene-3,17-dione and 120 mg of 19-nor-4-androstene-3,17-diol, total daily dose = 344 mg) on body composition and strength in resistance-trained men. In a placebo-controlled, double-blind, randomized fashion, 10 subjects received the norsteroid (11 capsules containing a combination of both norsteroids) or a placebo for 8 wk (five subjects per group). Each subject participated in resistance training an average of 4 d/wk for the duration of the study. Body composition was determined via dual-energy x-ray absorptiometry. Strength was determined using a one-repetition maximum bench press and a one-repetition maximum biceps curl. With regard to all measures in both groups, there were no significant changes between before and after the study.Therefore, in this small sample of resistance-trained men, 344 mg/d of norsteroid supplementation had no effect on strength or body composition.
van Gammeren
Darin
D
University of Florida, Center for Exercise Science, Gainesville 32611, USA. darinvg@ufl.edu
Falk
Darin
D
Antonio
Jose
J
D015502:Absorptiometry, Photon / Q000379:methods; D000328:Adult; D000734:Androstenediols / Q000008:administration & dosage / Q000494:pharmacology*; D000735:Androstenedione / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology*; D001823:Body Composition / Q000187:drug effects*; D019587:Dietary Supplements; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D016896:Treatment Outcome; D014891:Weight Lifting
C438965:19-nor-4-androstene-3,17-diol; D000734:Androstenediols; D000735:Androstenedione; C002828:19-norandrostenedione