title: [Primary high-grade B-cell lymphoma of the CNS. Case report and review of the literature].
abstract: We report the case of a 69-year-old patient referred to our clinic because of mania. When examined by neuroradiological imaging, there were lesions seen appearing and disappearing in different regions of the brain during a period of 2 months. Differential diagnosis of these changing lesions, progressive severe illness, and the role of glucocorticoid therapy concerning these lesions are discussed. The diagnosis of primary CNS lymphoma of the B-cell type could not made sure until autopsy.
authors.affiliation: Abteilung für Neurologie und Psychiatrie, Krankenhaus BHB Eggenberg, Bergstrasse 27, A-8021 Graz.
authors.forename: K
authors.initials: K
authors.lastname: Melinz
authors.forename: R M
authors.initials: RM
authors.lastname: Bonelli
authors.forename: G
authors.initials: G
authors.lastname: Niederwieser
authors.forename: L
authors.initials: L
authors.lastname: Kenner
authors.forename: F
authors.initials: F
authors.lastname: Reisecker
mesh_terms: D000368:Aged; D001706:Biopsy; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009460:Neurologic Examination / Q000187:drug effects; D014057:Tomography, X-Ray Computed
chemical_list: D008775:Methylprednisolone