title: The synapse assembly model.
abstract: A framework for quantitative analysis of the mechanisms underlying immunological synapse assembly has been recently developed. This model uses partial differential equations to describe the binding interactions of receptors and ligands, with the constraint that they are embedded in apposed deformable membranes linked to a cytoskeletal complex.
authors.affiliation: Biophysics Graduate Group, Dept of Chemistry, University of California, Berkeley, CA, USA.
authors.forename: Sung-Joo E
authors.initials: SJ
authors.lastname: Lee
authors.forename: Yuko
authors.initials: Y
authors.lastname: Hori
authors.forename: Jay T
authors.initials: JT
authors.lastname: Groves
authors.forename: Michael L
authors.initials: ML
authors.lastname: Dustin
authors.forename: Arup K
authors.initials: AK
authors.lastname: Chakraborty
mesh_terms: D000818:Animals; D006801:Humans; D007365:Intercellular Junctions / Q000276:immunology*; D007700:Kinetics; D008024:Ligands; D008433:Mathematics; D018448:Models, Immunological; D011971:Receptors, Immunologic / Q000378:metabolism
chemical_list: D008024:Ligands; D011971:Receptors, Immunologic