Lewis acid-promoted Baylis-Hillman-type reaction of alpha,beta-unsaturated ethyl thioester with aldehydes without the use of a Lewis base.
The Baylis-Hillman-type reaction of alpha,Beta-ethyl thioacrylate with aldehydes has been achieved using diethylaluminium iodide as the promoter without the direct use of any Lewis bases. The reaction provides an effective access to various alpha-methylene-Beta-hydroxy thioesters.
Pei
Wei
W
Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.
Wei
Han-Xun
HX
Li
Guigen
G
D000143:Acids / Q000737:chemistry; D000447:Aldehydes / Q000737:chemistry*; D002625:Chemistry, Organic; D004952:Esters / Q000737:chemistry*; D015394:Molecular Structure; D055601:Organic Chemistry Phenomena
D000143:Acids; D000447:Aldehydes; D004952:Esters