title: The distribution and morphology of calbindin D28K- and calretinin-immunoreactive neurons in the visual cortex of mouse.
abstract: We studied the distribution and morphology of calbindin D28K- and calretinin-immunoreactive (IR) neurons in the mouse visual cortex with immunocytochemistry. Most of the calbindin D28K-IR neurons were located in layers II/III and V, while calretinin-IR neurons were predominantly located in layers II/III. The labeled neurons showed variations in morphology. The majority of the calbindin D28K-IR neurons were stellate and round or oval cells with multipolar dendrites. The majority of calretinin-IR neurons were vertical fusiform cells with long processes traveling perpendicular to the pial surface. In the mouse visual cortex, 20.2% of calbindin D28K-IR neurons contained calretinin and 27.2% of calretinin-IR neurons contained calbindin D28K. These results indicate that the calcium-binding proteins, calbindin D28K and calretinin are distributed in specific layers and in selective cell types of the mouse visual cortex.
authors.affiliation: Department of Biology, College of Natural Sciences, College of Agriculture, Kyungpook National University, Daegu, Korea.
authors.forename: Hyun-Jung
authors.initials: HJ
authors.lastname: Park
authors.forename: Jee-Hyun
authors.initials: JH
authors.lastname: Kong
authors.forename: Youn-Sil
authors.initials: YS
authors.lastname: Kang
authors.forename: Won-Mee
authors.initials: WM
authors.lastname: Park
authors.forename: Seong-Ah
authors.initials: SA
authors.lastname: Jeong
authors.forename: So-Min
authors.initials: SM
authors.lastname: Park
authors.forename: Jin-Kyu
authors.initials: JK
authors.lastname: Lim
authors.forename: Chang-Jin
authors.initials: CJ
authors.lastname: Jeon
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D064092:Calbindin 1; D064032:Calbindin 2; D064026:Calbindins; D005455:Fluorescent Antibody Technique; D051379:Mice; D009474:Neurons / Q000166:cytology / Q000276:immunology*; D064030:S100 Calcium Binding Protein G / Q000276:immunology*; D014793:Visual Cortex / Q000166:cytology / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; C576499:Calb1 protein, mouse; C576511:Calb2 protein, mouse; D064092:Calbindin 1; D064032:Calbindin 2; D064026:Calbindins; D064030:S100 Calcium Binding Protein G