Are ultra-slow isoperiodic oscillations in rat intergeniculate leaflet neurons dependent on reciprocal connection with its contralaterally located counterpart?
We investigated effects of the electrical lesion and/or chemical inactivation of intergeniculate leaflet (IGL) neurons on the ultra-slow isoperiodic neuronal oscillation of the contralaterally located IGL. The spontaneous extracellular activity of neurons, recorded simultaneously in both leaflets of the lateral geniculate nucleus, showed an ultradian oscillatory pattern. In all our experiments, both the electrical lesion and the inactivation of neurons via the blockade of action potential generation did not cause any changes in the neuronal activity pattern in the contralaterally located geniculate leaflet. The obtained results show that a bilateral IGL connection is not necessary for the pattern of neuronal oscillation in the IGL. Hence the functional significance of a reciprocal connection between both lateral geniculate nucleus leaflets is still an open question.
Lewandowski
Marian H
MH
Department of Animal Physiology, Laboratory of Neurophysiology and Chronobiology, Institute of Zoology, Jagiellonian University, R Ingardena Str 6, 30060 Cracow, Poland. lew@zuk.iz.uj.edu.pl
Błasiak
Tomasz
T
Błasiak
Anna
A
D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D004556:Electric Injuries; D004569:Electroencephalography; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology*; D005829:Geniculate Bodies / Q000187:drug effects / Q000293:injuries / Q000502:physiology*; D008012:Lidocaine / Q000494:pharmacology; D008297:Male; D008839:Microelectrodes; D009434:Neural Pathways / Q000502:physiology; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D008012:Lidocaine