title: [Diagnostic protocol for unknown primary cancers. Review of 157 cases].
abstract: OBJECTIVE
  Decision-making to diagnose an Unknown Primary Cancer (UPC) is subject to great variability. It is possible to design a standard procedure using the scientífic literature, which seems to be able to avoid this variability. We describe the characteristics of the UPC in Asturias and measure the degree of adaptation of the diagnostic decisions to the theoretic standard procedure.
  
  
  METHODS
  Descriptive retrospective study (1992-96)
  
  
  RESULTS
  A pilot study included 157 cases: mean age 67 years and 59% male. The presentation form most frequent was hepatomegaly (29%) and histology: adenocarcinoma (51%). The diagnosis of the primary was possible in 22%: lung (31%). Median survival: 13 weeks, higher for squamous carcinoma, but independent of the diagnosis of the primary tumour. Comparing with the recommended protocol, the average of unnecessary diagnostic techniques per patient was: 8 analyses, 3 image studies and 0.6 unnecessary aggressive techniques.
  
  
  CONCLUSIONS
  The great variability in decision-making for diagnosing advises the application in of a diagnostic protocol that would avoid unnecessary damage for the patient and sanitary costs.
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad de Oviedo. casayoya@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Antuña Egocheaga
authors.forename: M L
authors.initials: ML
authors.lastname: López González
authors.forename: J
authors.initials: J
authors.lastname: Lobo Fernández
authors.forename: J
authors.initials: J
authors.lastname: Fernández Bustamante
authors.forename: J
authors.initials: J
authors.lastname: Moris de la Tassa
authors.forename: A
authors.initials: A
authors.lastname: Cueto Espinar
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis / Q000401:mortality; D012189:Retrospective Studies