Silence in the germ.
Gene expression in C. elegans germline cells is subject to strict controls. A set of MES proteins, including SET domain proteins and two homologs of Polycomb group proteins, establish an epigenetically transmitted silenced state that affects X chromosome gene expression.
Pirrotta
Vincenzo
V
Department of Zoology, University of Geneva, CH1211, Geneva, Switzerland. pirrotta@zoo.unige.ch
D000595:Amino Acid Sequence; D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology / Q000235:genetics* / Q000254:growth & development; D029742:Caenorhabditis elegans Proteins / Q000737:chemistry / Q000235:genetics; D002843:Chromatin / Q000235:genetics; D005260:Female; D018507:Gene Expression Regulation, Developmental; D020868:Gene Silencing; D005854:Germ Cells / Q000254:growth & development / Q000378:metabolism*; D008969:Molecular Sequence Data; D017434:Protein Structure, Tertiary; D016415:Sequence Alignment; D014960:X Chromosome
D029742:Caenorhabditis elegans Proteins; D002843:Chromatin