title: Littoral cell angioma of the spleen: appearance on sonography and CT.
abstract: Littoral cell angioma (LCA) is a rare benign vascular tumor of the spleen with characteristic histomorphologic features. Only a few descriptions of the radiologic appearance of this tumor have been published, and those descriptions are variable. We report a case of LCA in a 37-year-old man with psoriasis and nonspecific symptoms of weakness, pain and fatigue, normocytic anemia, and thrombocytopenia. The results of abdominal sonography and contrast-enhanced CT correlated: the 2 modalities revealed hepatosplenomegaly and multiple round splenic lesions of similar appearance and size (on sonograms, ill-defined echogenic lesions up to 3.2 cm without acoustic enhancement; on CT scans, hypodense, nonenhancing lesions up to 3.5 cm). Because making a differential diagnosis was difficult and our presumptive diagnosis was hemangioma or lymphoma, splenectomy was performed. Postoperative pathologic examinations confirmed a final diagnosis of LCA. The patient's recovery was uneventful. LCA should be considered when making a differential diagnosis of splenic lesions, and sonography may be more helpful than CT in reaching a diagnosis of LCA.
authors.affiliation: Department of Radiology, Western Galilee Hospital, POB 21, Nahariya, Israel.
authors.forename: Moshe
authors.initials: M
authors.lastname: Goldfeld
authors.forename: Isaac
authors.initials: I
authors.lastname: Cohen
authors.forename: Norman
authors.initials: N
authors.lastname: Loberant
authors.forename: Ahmed
authors.initials: A
authors.lastname: Mugrabi
authors.forename: Igor
authors.initials: I
authors.lastname: Katz
authors.forename: Sorin
authors.initials: S
authors.lastname: Papura
authors.forename: Ivan
authors.initials: I
authors.lastname: Noi
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography