Value of subcutaneous fat in predicting ovulation day.
Subcutaneous body fat and Quetelet's Indices (QI) of 52, 18-29 year old normal female volunteers were determined.  These body mass indices were then grouped according to the phase of each subject's menstrual cycle, early or late follicular and early or late luteal phase.  The subcutaneous body fat is 27.07 +or- 1.0% in the early follicular but drops to 24.68 +or- 1.84% in the late follicular phase.  The value then rises significantly higher than that in the late follicular phase to 30.14 +or- 1.15% (P0.02) in the early luteal drops to 27.17 +or- 0.55% towards the level of the early follicular phase (P0.05).  Variations in the values of QI during each menstrual cycle exactly mirror those for subcutaneous body fat.  The fall in the 2 body mass indices during the late follicular phase coincides somewhat with the established preovulatory LH and FSH surges as well as the high levels of estrogen of this period.  On the other hand the significant rise in the 2 parameters during the early luteal phase coincides with the marked rise in the ratio of progesterone to estrogen.  Clearly, increased levels of progesterone relative to estrogen appear to cause an increase in the body fat during each menstrual cycle.  The implication of this finding for women on contraceptive pills which are predominantly progesterone and those whose normal menstrual cycle is "interrupted" at the early luteal phase by a successful fertilization raises very interesting questions with regards to prediction of ovulation.
Jamaludin
J
J
Nordin
N M
NM
Mohamad
N
N
Etta
K M
KM
D000886:Anthropometry; D001208:Asia; D001210:Asia, Southeastern; D001695:Biology; D001835:Body Weight; D019411:Clinical Laboratory Techniques; D003267:Contraception; D003276:Contraceptives, Oral; D003906:Developing Countries; D003933:Diagnosis; D004703:Endocrine System; D004967:Estrogens; D005193:Family Planning Services; D005640:Follicle Stimulating Hormone; D006062:Gonadotropins; D006065:Gonadotropins, Pituitary; D006728:Hormones; D007986:Luteinizing Hormone; D008296:Malaysia; D008597:Menstrual Cycle; D008598:Menstruation; D010060:Ovulation; D010061:Ovulation Detection; D010827:Physiology; D011374:Progesterone; D011372:Progestins; D012098:Reproduction; D012106:Research; D012107:Research Design
D003276:Contraceptives, Oral; D004967:Estrogens; D006062:Gonadotropins; D006065:Gonadotropins, Pituitary; D006728:Hormones; D011372:Progestins; D011374:Progesterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Anthropometry; Asia; Biology; Body Weight--changes; Contraception; Contraceptive Methods; Developing Countries; Endocrine System; Estrogens--changes; Examinations And Diagnoses; Family Planning; Follicle Stimulating Hormone; Gonadotropins; Gonadotropins, Pituitary; Hormones; Laboratory Examinations And Diagnoses; Laboratory Procedures; Luteinizing Hormone; Malaysia; Measurement; Menstrual Cycle; Menstruation; Oral Contraceptives; Ovulation; Ovulation Detection; Physiology; Progestational Hormones; Progesterone--changes; Reproduction; Research Methodology; Southeastern Asia