Leaked protein and interstitial damage in the kidney: is complement the missing link?
Sheerin
N S
NS
Department of Nephrology and Transplantation, Guy's Hospital, King's College London, London, UK. neil.sheerin@kcl.ac.uk
Sacks
S H
SH
D000818:Animals; D015703:Antigens, CD; D002199:Capillary Permeability; D003167:Complement Activation; D015938:Complement Membrane Attack Complex / Q000652:urine; D003165:Complement System Proteins / Q000096:biosynthesis / Q000652:urine*; D016207:Cytokines / Q000096:biosynthesis; D018450:Disease Progression; D005355:Fibrosis; D005920:Glomerular Mesangium / Q000503:physiopathology; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism / Q000503:physiopathology*; D007687:Kidney Tubules, Proximal / Q000503:physiopathology; D051379:Mice; D008954:Models, Biological; D009395:Nephritis, Interstitial / Q000503:physiopathology*; D011507:Proteinuria / Q000503:physiopathology*; D044087:Receptor, Anaphylatoxin C5a; D011951:Receptors, Complement / Q000172:deficiency
D015703:Antigens, CD; D015938:Complement Membrane Attack Complex; D016207:Cytokines; D044087:Receptor, Anaphylatoxin C5a; D011951:Receptors, Complement; D003165:Complement System Proteins