title: Preliminary screening of some tropical plants for anti-tyrosinase activity.
abstract: In our efforts to find new active tyrosinase inhibitors for skin-whitening or antibrowning preparations, we investigated 67 tropical plants belonging to 38 families, which were evaluated for their anti-tyrosinase activity. The results of our investigation show that extracts of 5 plants, Stryphnodendron barbatimao, Portulaca pilosa, Cariniana brasiliensis, Entada africana and Prosopis africana present interesting in vitro mushroom tyrosinase inhibition (over 90%), similar to a positive control: Morus alba. These 5 plants will be studied in order to isolate and identify phytochemical compounds, involved in this biological activity.
authors.affiliation: GREENPHARMA S.A., 3 allée du Titane, 45100 Orleans, France.
authors.forename: N
authors.initials: N
authors.lastname: Baurin
authors.forename: E
authors.initials: E
authors.lastname: Arnoult
authors.forename: T
authors.initials: T
authors.lastname: Scior
authors.forename: Q T
authors.initials: QT
authors.lastname: Do
authors.forename: P
authors.initials: P
authors.lastname: Bernard
mesh_terms: D000363:Agaricales / Q000201:enzymology; D004353:Drug Evaluation, Preclinical / Q000379:methods / Q000706:statistics & numerical data*; D004791:Enzyme Inhibitors / Q000302:isolation & purification / Q000494:pharmacology*; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D018514:Plant Structures
chemical_list: D004791:Enzyme Inhibitors; D010936:Plant Extracts; D014442:Monophenol Monooxygenase