title: Post-renal acute renal failure during pelvis irradiation for prostate cancer.
abstract: A case of post renal acute renal failure secondary to radiation therapy for prostate cancer is described. Severe bladder inflammatory reaction, leading to bilateral ureteric obstruction, occurred after a moderate dose of radiotherapy (6400 cGy in 35 fractions). At a follow-up time of 8 years, the patient has fully recovered and remains disease-free. To our knowledge, this complication has never been described previously. Given the thrust in prostate cancer treatment toward dose escalation this complication could become more frequent.
authors.affiliation: Department of Radiation Oncology, McGill University, Montreal, Quebec, Canada.
authors.forename: Marc
authors.initials: M
authors.lastname: David
authors.forename: Luis
authors.initials: L
authors.lastname: Souhami
authors.forename: Armen
authors.initials: A
authors.lastname: Aprikian
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000368:Aged; D006801:Humans; D008297:Male; D010388:Pelvis; D011471:Prostatic Neoplasms / Q000150:complications / Q000532:radiotherapy*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*