Cytosolic glucocorticoid receptor-interacting proteins.
Studies of GR-interacting proteins can provide valuable insights into the regulation of GR cellular signalling. The cytoplasmic localization of GR and reports of GR interaction with such a plethora of other cytoplasmic proteins may point to a unique role for GR in modulating and integrating other signalling pathways. A better insight into these interactions could serve as a tool when trying to understand and modify GR signalling.
D048948:14-3-3 Proteins; D003598:Cytoskeletal Proteins / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism*; D006801:Humans; D018832:Molecular Chaperones / Q000378:metabolism; D016328:NF-kappa B / Q000378:metabolism; D011485:Protein Binding; D019908:Proto-Oncogene Proteins c-raf / Q000378:metabolism; D011965:Receptors, Glucocorticoid / Q000378:metabolism*; D014446:Tyrosine 3-Monooxygenase / Q000378:metabolism
D048948:14-3-3 Proteins; D003598:Cytoskeletal Proteins; D018832:Molecular Chaperones; D016328:NF-kappa B; D011965:Receptors, Glucocorticoid; D014446:Tyrosine 3-Monooxygenase; D019908:Proto-Oncogene Proteins c-raf