Effect of imbalance in plasma oxidant homeostasis on the choice of stromal differentiation of polypotent bone marrow stem cells in mice receiving estrone injection.
The choice of stromal differentiation by polypotent stem cells was studied by morphological and chemiluminescent methods. The differentiation pathway is selected on day 7 after heterotopic bone marrow transplantation and injection of estrone. The imbalance in plasma oxidant homeostasis in mice on day 7 after estrone injection is associated with drastic intensification of free-radical oxidation and blockade of antioxidant activity.
D000818:Animals; D002454:Cell Differentiation; D004970:Estrone / Q000008:administration & dosage*; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006706:Homeostasis; D008163:Luminescent Measurements; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D016877:Oxidants / Q000097:blood*; D017154:Stromal Cells / Q000166:cytology*
D016877:Oxidants; D004970:Estrone