An efficient synthesis of endo,exo-furofuranone derivatives.
The ring openings of 1-acetyl-4-phenyl-3-oxabicyclo[3.1.0]hexane afforded alpha-acetyl-gamma-butyrolactone that underwent a novel diazo-transfer reaction, followed by C-H insertion, to provide a series of endo,exo-furofuranone analogues.
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis*; D006586:Hexanes / Q000737:chemistry
D005663:Furans; D006586:Hexanes; D015107:4-Butyrolactone