[Features of ulcer disease in elderly patients with ischemic heart disease].
The purpose of this research is to study the clinical current of stomach and duodenal ulcer disease in a combination with the ischemic heart disease (IHD). The group of 290 patients with IHD in a combination with SUD and DUD were examined. The clinical-laboratory researches, histological analysis of stomach mucosa bioptates (SMB) and duodenal mucosa bioptates (DMB) were spend. In persons with IHD the stomach ulcers are observed (56%) more often than duodenal ulcers. The lesser curvature and pillory part of stomach were affected more often. In male the ulcers were met 3.5 times more often than in female. It was marked the tendency to the painless current of ulcer disease (UD). There were no the seasonal prevalence of exacerbations. In 52% of the patients the first manifestations of the disease were the gastric bleedings. The UD current differed by often relapses and long exacerbations (76%), which have coincided with the IHD exacerbations. In 68% of the patients the UD exacerbations were marked at the first 10 days after the myocardial infarction or aortocoronary shunting. The role of Helicobacter pylori as a causative factor of UD is marked in 26% of the patients. In 62% of the patients the basic role in UD exacerbation played the microcirculatory disorders, lowering of bloodstream in stomach mucosa or duodenal mucosa, syndrome of hypocoagulation, dislipidemia. In stomach and duodenal mucosa bioptates the dystrophic changes were expressed. The formation of ulcers and erosions of mucosa of gastrointestinal path in IHD patients are probably connected with blood circulation disorders in SM. The main aggression factors are the hypoxia, accompanying trophic disorders of SM and DM, the changes in vascular system.
D000368:Aged; D001706:Biopsy; D004381:Duodenal Ulcer / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications*; D013276:Stomach Ulcer / Q000150:complications / Q000473:pathology*
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