Treatment of chronic ischaemia of a replanted thumb with iloprost.
A 40-year-old man had chronic ischaemia of his replanted thumb. Angiography revealed occlusion of both digital arteries and weak collaterals. He was treated for 4 weeks with Iloprost which produced a definite and sustained improvement. As the digital arteries remained occluded, the beneficial effect of Iloprost was attributed to increased flow in the microcirculation and collaterals.
D000328:Adult; D000673:Amputation, Traumatic / Q000150:complications / Q000601:surgery; D002908:Chronic Disease; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use*; D007511:Ischemia / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D012092:Replantation / Q000009:adverse effects*; D013933:Thumb / Q000293:injuries / Q000601:surgery*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D014665:Vasodilator Agents; D016285:Iloprost