An enantioselective synthetic pathway towards plakortones.
An enantioselective synthesis of functionalized bicyclic lactones 2, 3 and 4, core structures of plakortones, are described; the configurations of 2, 3 and 4 were confirmed by X-ray crystallographic analyses of their precursors 11, 19 and 24, respectively.
D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D019086:Bridged Bicyclo Compounds, Heterocyclic; D007783:Lactones