title: The use of pressure immobilization bandages in the first aid management of cubozoan envenomings.
abstract: This study is aimed to evaluate whether the application of pressure results in additional release of venom from naturally discharged, vinegar soaked nematocysts of the box jellyfish Chironex fleckeri. The results show that large quantities of venom are expressed with the application of pressures similar to that applied by compression immobilization bandages. The volume of venom expressed by this pressure was similar to the quantity expressed upon initial natural discharge of the nematocysts. The current recommended practice of applying PIB to cubozoan stings might worsen the envenomation. As the existing data now show that PIB may be detrimental to victims envenomed by cubozoans, we suggest that the current practice of the use of PIB in cubozoan envenomings be discarded until there is direct experimental evidence to support its use.
mesh_terms: D019342:Acetic Acid; D000818:Animals; D001458:Bandages; D001681:Biological Assay; D001733:Bites and Stings / Q000628:therapy*; D003064:Cnidarian Venoms / Q000032:analysis / Q000378:metabolism* / Q000506:poisoning; D000075202:Contraindications; D037462:Cubozoa / Q000502:physiology*; D005392:First Aid / Q000379:methods*; D011312:Pressure; D011506:Proteins / Q000032:analysis
chemical_list: D003064:Cnidarian Venoms; D011506:Proteins; D019342:Acetic Acid