Determination of CMC of sodium glucocorticides hemisuccinates by CE.
The capillary zone electrophoresis (CZE) method was applied to the determination of the critical micelle concentration (CMC) and the anionic mobilities (mu(e)) for sodium glycocorticides hemisuccinates (Urbason solubile forte 1000, Hydrocortison 100 Rotexmedica, Prednisolut 100) in phosphate solution at pH 7.2. The CZE enables an efficient and very fast determination of parameters for characterizing physicochemical properties of micelles.
D019075:Electrophoresis, Capillary / Q000379:methods; D006854:Hydrocortisone / Q000031:analogs & derivatives* / Q000032:analysis*; D008775:Methylprednisolone / Q000032:analysis*; D008823:Micelles; D012964:Sodium / Q000032:analysis* / Q000737:chemistry; D012996:Solutions; D013386:Succinates / Q000032:analysis* / Q000737:chemistry
D008823:Micelles; D012996:Solutions; D013386:Succinates; D012964:Sodium; C007133:hydrocortisone hemisuccinate; D006854:Hydrocortisone; D008775:Methylprednisolone