Chronic obstructive pulmonary disease * 3: Experimental animal models of pulmonary emphysema.
The use of genetically manipulated mice together with traditional animal studies are steadily increasing our knowledge of the factors important in determining alveolar formation and destruction in emphysema. A review of the animal models used to study emphysema is presented.
D000818:Animals; D004195:Disease Models, Animal; D018390:Gene Targeting; D005818:Genetic Engineering; D051379:Mice; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D009154:Mutation / Q000235:genetics; D029424:Pulmonary Disease, Chronic Obstructive / Q000209:etiology*; D011656:Pulmonary Emphysema / Q000139:chemically induced / Q000209:etiology*