Uveitic angle closure glaucoma in a patient with inactive cytomegalovirus retinitis and immune recovery uveitis.
We report a case of uveitic acute angle closure glaucoma in a patient with acquired immunodeficiency syndrome (AIDS) associated with inactive cytomegalovirus retinitis and immune recovery vitritis. We conducted a long-term, follow-up examination of a 47-year-old male with AIDS and inactive cytomegalovirus retinitis caused by immune recovery on highly active antiretroviral therapy (HAART). We found vitritis and ultimate development of uveitic glaucoma in the postoperative periods following repair of retinal detachment and extracapsular cataract extraction with intraocular lens implant. An episode of acute angle closure secondary to posterior synechiae and iris bombé subsequently developed, requiring peripheral laser iridotomy. Immune recovery in the setting of inactive cytomegalovirus retinitis can result in intraocular inflammation severe enough to cause angle closure glaucoma and profound ocular morbidity.
D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000208:Acute Disease; D023241:Antiretroviral Therapy, Highly Active; D017726:Cytomegalovirus Retinitis / Q000150:complications*; D005128:Eye Diseases / Q000150:complications*; D015812:Glaucoma, Angle-Closure / Q000209:etiology*; D015497:HIV-1; D006801:Humans; D007429:Intraocular Pressure; D032801:Iridectomy / Q000379:methods; D053685:Laser Therapy / Q000379:methods; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014606:Uveitis, Anterior / Q000209:etiology*; D014792:Visual Acuity; D014822:Vitreous Body / Q000473:pathology*