Towards Alzheimer's disease vaccination.
Active and passive immunization against fibrillar beta-amyloid of various mice models of Alzheimer's disease leads to the disaggregation and inhibition of plaque formation. Preliminary results showing improved behaviour and memory function obtained after administration of anti-beta-amyloid vaccines to transgenic mice encourage these and related approaches for testing in the treatment and prevention of Alzheimer's disease.
D000544:Alzheimer Disease / Q000473:pathology / Q000517:prevention & control*; D016229:Amyloid beta-Peptides / Q000737:chemistry / Q000276:immunology*; D000818:Animals; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D014611:Vaccination
D016229:Amyloid beta-Peptides