Genetic susceptibility to chronic periodontal disease.
Evidence suggests that there is a significant genetic component to susceptibility and resistance to chronic periodontal disease. Data from both clinical studies and studies using animal models are reviewed here. Also outlined are the genomic methods that are now available for identifying susceptibility and resistance loci.
D000818:Animals; D002908:Chronic Disease; D004195:Disease Models, Animal; D004198:Disease Susceptibility / Q000175:diagnosis; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D051379:Mice; D008806:Mice, Inbred AKR; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D010510:Periodontal Diseases / Q000453:epidemiology / Q000235:genetics* / Q000382:microbiology