The Orphan Drug Act: an engine of innovation? At what cost?
D017277:Drug Approval; D016527:Drug Costs; D004345:Drug Industry / Q000266:history; D004465:Economic Competition / Q000331:legislation & jurisprudence; D049673:History, 20th Century; D006801:Humans; D008389:Marketing of Health Services / Q000331:legislation & jurisprudence; D009936:Organizational Innovation; D009965:Orphan Drug Production / Q000191:economics / Q000331:legislation & jurisprudence*; D014481:United States; D014486:United States Food and Drug Administration