title: Lateral interactions in amblyopia.
abstract: We studied lateral neural interactions in strabismic (n=6) and anisometropic amblyopes (n=3) by measuring reductions in the perceived contrast of a foveally viewed Gabor centred in a horizontal array of closely neighboring Gabors. Strabismic amblyopes, but not anisometropic amblyopes, failed to show the reduction in perceived contrast typical of normal vision [J. Opt. Soc. Amer. A 15 (1998) 1733] when lateral contrast information is available at the same orientation and spatial frequency. The strabismic amblyopes also severely misperceive the regularity of the array of Gabors flanking the test stimulus. A normal eye could model the anomalous contrast perception of the amblyopic eye, by adding an equivalent amount of spatial distortion to the stimulus. The relationship between the observed anomalies for local contrast gain control and positional sensitivity is discussed.
mesh_terms: D000328:Adult; D000550:Amblyopia / Q000523:psychology*; D015858:Anisometropia / Q000523:psychology; D015350:Contrast Sensitivity; D006801:Humans; D008875:Middle Aged; D013285:Strabismus / Q000523:psychology; D014787:Vision Tests; D014792:Visual Acuity