Drug-facilitated sexual assault involving gamma-hydroxybutyric acid.
The first case involving an alleged sexual assault linked to the use of gamma-hydroxybutyric acid (GHB) in Oklahoma is reported. A-48-year-old Caucasian woman taking amitriptyline was known to have voluntarily ingested a sports drink containing a relaxing health product. She purportedly experienced unconsciousness that persisted for approximately 4 h. The toxicological testing on urine identified GHB, amitriptyline, and nortriptyline using a capillary Hewlett-Packard 6890 gas chromatograph coupled to a Hewlett-Packard 5973 mass selective detector (MSD). The GHB concentration in urine was 26.9 microg/mL. Urine concentrations of amitriptyline and nortriptyline were not determined. The analytical method used for identifying and quantitating GHB can be applied to matters of forensic interests.
D000328:Adult; D000639:Amitriptyline / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006885:Hydroxybutyrates / Q000009:adverse effects* / Q000494:pharmacology; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D011902:Rape; D019966:Substance-Related Disorders; D014474:Unconsciousness; D016482:Urinalysis
D000929:Antidepressive Agents, Tricyclic; D006885:Hydroxybutyrates; D000639:Amitriptyline; C111420:4-hydroxybutyric acid