Human exposure to fipronil from dogs treated with frontline.
This investigation determined fipronil residues on gloves worn while petting dogs after Frontline application. Frontline contains 9.8% fipronil, which controls fleas and ticks on dogs for at least 30 d. Frontline (1.34 ml) was applied topically on adult household dogs and gloves worn for 5 min during pettingwere collected 24 hr and 1, 2, 3, 4 and 5 w post-Frontline application for fipronil residue determinations using GC/MS. The highest concentration of fipronil (589.3 +/- 205.7ppm) was detected 24 h after Frontline application and was undetectable in the gloves collected at 5w. Repeated exposure to such contamination can pose human health risks.
D000818:Animals; D004285:Dogs; D008401:Gas Chromatography-Mass Spectrometry; D017575:Gloves, Protective; D006801:Humans; D007306:Insecticides / Q000032:analysis* / Q000506:poisoning; D007928:Lethal Dose 50; D016273:Occupational Exposure; D010573:Pesticide Residues / Q000032:analysis* / Q000506:poisoning; D011720:Pyrazoles / Q000032:analysis* / Q000506:poisoning; D051381:Rats
D007306:Insecticides; D010573:Pesticide Residues; D011720:Pyrazoles; C082360:fipronil