Pauci-immune extracapillary glomerulonephritis and atheromatous embolization.
Renal atheroembolic disease presents several multisystemic signs and symptoms that may resemble the clinical signs of vasculitis. A few cases of renal atheroembolism associated with antineutrophil cytoplasmic antibodies (ANCA) have been described. We report the first case, to our knowledge, of a patient with cholesterol microemboli who also developed extracapillary glomerulonephritis in the presence of perinuclear ANCA (p-ANCA) with anti-myeloperoxidase ANCA. The patient had long-term follow-up of renal function after treatment with prednisone and cyclophosphamide.
D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood / Q000378:metabolism; D001161:Arteriosclerosis / Q000150:complications* / Q000188:drug therapy; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D003937:Diagnosis, Differential; D017700:Embolism, Cholesterol / Q000188:drug therapy / Q000209:etiology*; D005921:Glomerulonephritis / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000276:immunology; D008297:Male; D009195:Peroxidase / Q000276:immunology; D012078:Renal Artery Obstruction / Q000188:drug therapy / Q000209:etiology*
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies; D009195:Peroxidase