Finger arterial compliance as determined by transmission of light during mental stress and reactive hyperaemia.
A near-infrared finger photoplethysmogram adopting a wavelength of 810 nm provides data pertaining to the pulsatile a.c. component of finger blood flow (delta I) superimposed on the transmitted d.c. components in a normal ( I: tissue plus blood) and an ischaemic circulatory state ( I(t): tissue only). Simultaneous recording of finger blood pressure provides data pertaining to the distending pulse (PP) and mean blood pressure. Based on the Lambert-Beer law, indices of the arterial compliance (CI=delta I/ I/PP) and distensibility [DI=delta I/ I/ln( I(t)/ I)/PP] are advocated for assessing finger vasculature. The functional relationships between transmural pressure and CI and DI were examined using finger occlusion while performing an arithmetic test (i.e. a mental stress) in 16 females, and during reactive hyperaemia in 5. Gradual occlusion of the finger was conducted at 20-s intervals and the beat-by-beat transmural pressure was determined by calculating mean blood pressure minus the occluding cuff pressure. Logarithmically transformed CI and DI data were linearly associated with the transmural pressure; thus, the estimates obtained at a transmural pressure of 40 mmHg were chosen as an arbitrary reference point (CI40 and DI40). The results indicated that CI40 and DI40 were reduced while performing an arithmetic test, and increased during reactive hyperaemia. Responses were larger for CI40 than for DI40. In conclusion, noninvasive finger occlusion allowed the measurement of the compliance/distending pressure relationship, and CI40 could be utilised to evaluate changes in finger vascular tone.
D000328:Adult; D001158:Arteries / Q000502:physiology; D003187:Compliance; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D006940:Hyperemia / Q000503:physiopathology*; D008027:Light; D017156:Photoplethysmography; D012039:Regional Blood Flow / Q000502:physiology*; D012044:Regression Analysis; D013315:Stress, Psychological / Q000503:physiopathology*