title: Adrenocorticotropin-like immunoreactivity in the granules of neural complex cells of the ascidian Halocynthia roretzi.
abstract: Immunohistochemical studies on the neural complex (neural gland, dorsal strand, and cerebral ganglion) of an ascidian, Halocynthia roretzi, were performed by using an antiserum against porcine ACTH. The antiserum recognized a considerable number of the cells scattered along the tubular structure of the dorsal strand and a few cells in the cerebral ganglion. Immunoelectron microscopic studies revealed that the ACTH-like substance resided within secretory granules with diameter of 300-500 nm. Furthermore, those ACTH-immunoreactive cells were demonstrated to be different from PRL-immunoreactive cells, the presence of which had previously been reported.
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000032:analysis* / Q000276:immunology; D000818:Animals; D007150:Immunohistochemistry; D016253:Microscopy, Immunoelectron; D009420:Nervous System / Q000737:chemistry* / Q000166:cytology* / Q000648:ultrastructure; D022142:Secretory Vesicles / Q000737:chemistry* / Q000648:ultrastructure; D014561:Urochordata / Q000737:chemistry* / Q000166:cytology* / Q000648:ultrastructure
chemical_list: D000324:Adrenocorticotropic Hormone