Idiopathic autoimmune thrombocytopenia and neutropenia in siblings.
Familial incidences of autoimmune disorders involving red cells, white cells and platelets are rare. Two cases of autoimmune neutropenia and thrombocytopenia occurring in two adult brothers are reported here. One patient showed prompt recovery of white cells with steroids but needed IV IgG+ splenectomy for durable platelet recovery. His brother required splenectomy for durable recovery of white cells and platelets as he showed transient recovery with steroids and IV IgG.
D000328:Adult; D006801:Humans; D008297:Male; D009503:Neutropenia; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000235:genetics* / Q000503:physiopathology; D035781:Siblings