title: A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery.
abstract: OBJECTIVE
  To introduce and evaluate the infusion and aspiration rates and operative times of the 25-gauge transconjunctival sutureless vitrectomy system (TSV) DESIGN: In vitro experimental and comparative interventional study.
  
  
  METHODS
  Twenty eyes of 20 patients underwent a variety of vitreoretinal procedures using the 25-gauge TSV, including idiopathic epiretinal membrane (n = 10), macular hole (n = 4), rhegmatogenous retinal detachment (n = 3), branch retinal vein occlusion (n = 2), diabetic vitreous hemorrhage (n = 1), and 20 cases similar in diagnosis and severity were matched to provide comparison between duration of individual portions of the surgical procedures with the existing 20-gauge vitrectomy system.
  
  
  METHODS
  Description of the 25-gauge TSV is provided; infusion and aspiration rates of the 25-gauge and standard 20-gauge vitrectomy system were measured in vitro using balanced saline solution and porcine vitreous for several levels of aspirating power and bottle height, and operating times of individual portions of surgical procedures were measured for the 25-gauge and 20-gauge vitrectomy system.
  
  
  METHODS
  Infusion, aspiration rates, and operative times of the 20-gauge and 25-gauge vitrectomy system.
  
  
  RESULTS
  Infusion and aspiration rates of the 25-gauge TSV system were reduced by an average of 6.9 and 6.6 times, respectively, compared with the 20-gauge system when balanced saline solution was used. The average flow rate of the Storz 25-gauge cutter (at 500 mmHg, 1500 cuts per minute [cpm]) was 40% greater than that of the 20-gauge pneumatic cutter (at 250 mmHg, 750 cpm) but about 2.3 times less than the 20-gauge high-speed cutter (at 250 mmHg, 1500 cpm). Mean total operative time was significantly greater for the 20-gauge high-speed cutter (26 minutes, 7 seconds) than for the 25-gauge vitrectomy system (17 minutes, 17 seconds) (P = 0.011).
  
  
  CONCLUSIONS
  Although the infusion and aspiration rates of the 25-gauge instruments are lower than those for the 20-gauge high-speed vitrectomy system, the use of 25-gauge TVS may effectively reduce operative times of select cases that do not require the full capability of conventional vitrectomy.
mesh_terms: D048909:Diabetes Complications; D004322:Drainage; D019773:Epiretinal Membrane / Q000601:surgery; D004867:Equipment Design; D006801:Humans; D019060:Minimally Invasive Surgical Procedures; D012163:Retinal Detachment / Q000601:surgery; D012164:Retinal Diseases / Q000601:surgery*; D012167:Retinal Perforations / Q000601:surgery; D012170:Retinal Vein Occlusion / Q000601:surgery; D013537:Sutures; D013997:Time Factors; D016896:Treatment Outcome; D014821:Vitrectomy / Q000295:instrumentation*; D014823:Vitreous Hemorrhage / Q000209:etiology / Q000601:surgery*