Viral load in Epstein-Barr virus-associated hemophagocytic syndrome.
The viral load in peripheral blood from patients with Epstein-Barr virus (EBV)-associated hemophagocytic syndrome was measured by real-time quantitative PCR and compared with that in infectious mononucleosis. Patients with EBV-associated hemophagocytic syndrome generally had larger viral burdens, although it was difficult to differentiate EBV-associated hemophagocytic syndrome from infectious mononucleosis simply by viral load. The difference in viral load seemed to be clearer in peripheral blood mononuclear cells than in plasma.
D000328:Adult; D004279:DNA, Viral / Q000097:blood*; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D007223:Infant; D007244:Infectious Mononucleosis / Q000821:virology; D007963:Leukocytes, Mononuclear / Q000821:virology; D016133:Polymerase Chain Reaction / Q000379:methods; D019562:Viral Load
D004279:DNA, Viral