title: Variation in vector competence for dengue 2 virus among 24 collections of Aedes aegypti from Mexico and the United States.
abstract: Aedes aegypti from 24 collections in Mexico and the United States were challenged orally with dengue 2 virus JAM1409 (DEN-2 JAM1409). The vector competence (VC) of the populations ranged from 24% to 83%. Mosquito populations from the Yucatan exhibited greater VC than those from other areas of Mexico. The presence or absence of a midgut infection barrier (MIB) and a midgut escape barrier (MEB) was determined for mosquitoes in each population. The percentage of mosquitoes exhibiting an MIB ranged from 14% to 59%, and those exhibiting an MEB ranged from 4% to 43% in the collections. The MIB and MEB were not completely independent as determined by regression analysis. Midgut infection rates were dose dependent.
mesh_terms: D000330:Aedes / Q000821:virology*; D000818:Animals; D003715:Dengue / Q000635:transmission; D003716:Dengue Virus / Q000302:isolation & purification*; D007303:Insect Vectors; D008800:Mexico; D014481:United States