title: Near infrared transflectance spectroscopy: determination of dexketoprofen in a hydrogel.
abstract: A new method for the determination of the active principle dexketoprofen (DKP) in a hydrogel using near infrared spectrometry was developed. A transflectance module allows the gel spectrum to be recorded with no sample pretreatment. Also, the PLS calibration method used allows low contents of the active principle in such a highly absorbing matrix as water/ethanol to be determined. The proposed method was validated and found to be an effective choice for the intended purpose.
mesh_terms: D020100:Hydrogels / Q000032:analysis* / Q000737:chemistry; D007660:Ketoprofen / Q000031:analogs & derivatives* / Q000032:analysis* / Q000737:chemistry; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D014325:Tromethamine / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry
chemical_list: D020100:Hydrogels; D014325:Tromethamine; D007660:Ketoprofen; C118296:dexketoprofen trometamol