Motoring around the Golgi.
The Golgi apparatus is a dynamic organelle through which nascent secretory and transmembrane proteins are transported, post-translationally modified and finally packaged into carrier vesicles for transport along the cytoskeleton to a variety of destinations. In the past decade, studies have shown that a number of 'molecular motors' are involved in maintaining the proper structure and function of the Golgi apparatus. Here, we review just some of the many functions performed by these mechanochemical enzymes - dyneins, kinesins, myosins and dynamin - in relation to the Golgi apparatus.
D000818:Animals; D034281:Dynamins / Q000378:metabolism; D004398:Dyneins / Q000378:metabolism; D006056:Golgi Apparatus / Q000378:metabolism* / Q000648:ultrastructure; D006801:Humans; D016547:Kinesins / Q000378:metabolism; D020409:Molecular Motor Proteins / Q000378:metabolism*; D009218:Myosins / Q000378:metabolism; D014176:Protein Biosynthesis; D021381:Protein Transport / Q000502:physiology*; D011506:Proteins / Q000378:metabolism; D022161:Transport Vesicles / Q000378:metabolism / Q000648:ultrastructure
D020409:Molecular Motor Proteins; D011506:Proteins; D009218:Myosins; D004398:Dyneins; D016547:Kinesins; D034281:Dynamins