The first orally active low molecular weight agonists for the LH receptor: thienopyr(im)idines with therapeutic potential for ovulation induction.
D000284:Administration, Oral; D000818:Animals; D016466:CHO Cells / Q000378:metabolism; D006224:Cricetinae; D004958:Estradiol / Q000138:chemical synthesis; D005260:Female; D006801:Humans; D007985:Leydig Cells / Q000737:chemistry / Q000187:drug effects; D008297:Male; D051379:Mice; D008970:Molecular Weight; D010062:Ovulation Induction / Q000379:methods*; D010063:Ovum / Q000187:drug effects; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011962:Receptors, FSH / Q000187:drug effects; D011974:Receptors, LH / Q000819:agonists* / Q000378:metabolism / Q000627:therapeutic use; D013739:Testosterone / Q000096:biosynthesis; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
C510603:Org 41841; D011725:Pyridines; D011743:Pyrimidines; D011962:Receptors, FSH; D011974:Receptors, LH; D013876:Thiophenes; C446540:thienopyridine; D013739:Testosterone; D004958:Estradiol