[The influence of oral contraceptive no. II on platelet function and blood coagulability].
The influence of the No. II oral contraceptive on platelet function and blood coagulability were studied in 65 women who had taken the drug for 1 to 17 (average 6.7) years.  20 women who hadn't taken any contraceptive served as controls.  Results showed that platelet aggregation, adhesive rates, and fibrinogen levels were significantly increased than in the control group (P0.001).  Factor VIII related antigen was slightly elevated, but not statistically significant.  Antithrombin activity was significantly decreased (P0.001).  The possibility of acute myocardial infarction and thromboembolic diseases are discussed and measures for prevention suggested.
D001208:Asia; D001695:Biology; D001769:Blood; D001777:Blood Coagulation; D002319:Cardiovascular System; D002560:Cerebrovascular Circulation; D002681:China; D003267:Contraception; D003276:Contraceptives, Oral; D003906:Developing Countries; D005193:Family Planning Services; D005202:Asia, Eastern; D006331:Heart Diseases; D009203:Myocardial Infarction; D010827:Physiology; D010974:Platelet Aggregation; D013923:Thromboembolism; D014652:Vascular Diseases
D003276:Contraceptives, Oral
Asia; Biology; Blood Coagulation Effects; Cardiovascular Effects; Cerebrovascular Effects; China; Contraception; Contraceptive Methods; Developing Countries; Eastern Asia; Family Planning; Heart Diseases; Hematological Effects; Hemic System; Myocardial Infarction; Oral Contraceptives; Physiology; Platelet Aggregation; Thromboembolism; Vascular Diseases