title: [Histopathology of the hypothalamus and the neural lobe of hypophysis in suicide victims].
abstract: Histologic studies of the hypothalamus and neurohypophysis revealed that in young (17-35 y. o.) suicide victims, there are degenerative changes in the supraoptic and paraventricular nuclei and partial destruction by inflammation of the neurohypophysis. Simultaneously foci of micromalaic and the gatuering of azurophilic material in neuronal perikarya around the cerebral blood vessel and the leptomeninges. The degenerated neurones contain great vacuoles, often filled with lipofuscin. The probable pathogenic mechanism of the observed changes is discussed with its influence on mood-lowering leading to suicide.
mesh_terms: D000293:Adolescent; D000328:Adult; D002102:Cadaver; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000473:pathology*; D008297:Male; D009474:Neurons; D010286:Paraventricular Hypothalamic Nucleus / Q000473:pathology; D010904:Pituitary Gland, Posterior / Q000473:pathology*; D013405:Suicide; D013495:Supraoptic Nucleus / Q000473:pathology
vernacular_title: Histopatologia podwzgórza i tylnego płata przysadki w przypadku śmierci samobójczej.