Phagocytosis: how the phagosome became the phag-ER-some.
Phagocytosis is a fundamental mechanism for engulfment of pathogens, dead and dying host cells and other particulate material. Surprisingly, the involvement of the endoplasmic reticulum in macrophage-mediated phagocytosis has only just been discovered.
D000818:Animals; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D015395:Histocompatibility Antigens Class I / Q000378:metabolism; D008264:Macrophages / Q000166:cytology* / Q000378:metabolism*; D010587:Phagocytosis; D010588:Phagosomes / Q000378:metabolism*; D021381:Protein Transport
D015395:Histocompatibility Antigens Class I