title: Exacerbation of pulmonary sarcoidosis after liver transplantation.
abstract: Patients with hepatic sarcoidosis rarely require orthotopic liver transplantation (OLT). Progression of granulomatous activity involving other organs after OLT has rarely been described. We describe a 32-year-old woman who underwent liver transplantation for sarcoidosis-associated end-stage liver disease. She presented 4 years later with shortness of breath, hilar lymphadenopathy, and interstitial lung abnormalities. Liver functions were normal. Open lung biopsy results revealed granulomata compatible with sarcoidosis. The patient made a complete recovery after corticosteroid treatment. To the best of our knowledge, this is a first description of severe exacerbation of pulmonary sarcoidosis in an immunosuppressed patient who underwent liver transplantation for sarcoidosis-associated liver disease.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017093:Liver Failure / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects*; D017565:Sarcoidosis, Pulmonary / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D014057:Tomography, X-Ray Computed