title: Echocardiographic diagnosis of apical hypertrophic cardiomyopathy with optison contrast.
abstract: We describe a case of obstructive apical hypertrophic cardiomyopathy in a 61-year-old Caucasian female with a history of chest pain syndrome. The patient was referred to the echo lab by her nuclear cardiologist, who was impressed by her abnormal stress nuclear perfusion scan that showed marked increased uptake of radioisotope at the left ventricular (LV) apex. The patient had deep negative T waves on her electrocardiogram similar to those originally described in the Japanese population. Transthoracic echocardiography with native harmonic imaging was suboptimal for visualizing LV segments. Therefore, 0.5 cc of Optison contrast was given intravenously, with repeat transthoracic imaging confirming the diagnosis. The patient and her family were referred for additional genetic testing and cardiovascular workup.
mesh_terms: D000418:Albumins; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging*; D003287:Contrast Media; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D005466:Fluorocarbons; D006801:Humans; D008863:Microspheres; D008875:Middle Aged
chemical_list: D000418:Albumins; D003287:Contrast Media; C099458:FS 069; D005466:Fluorocarbons