title: [Combined treatment of persisting urogenital chlamydia infection with sumamed and interferon alfa].
abstract: The results of complex treatment of 235 patients with persisting urogenital chlamidial infection are presented. The treatment regime included immunotropic agent interferone alfa-alpha 2b and antibiotic azithromycin (Sumamed, "Pliva", Croatia) 1 g per day 3 times every 7 days. Chlamidial persistence diagnosis was performed by culture method (determination of small cytoplasmic inclusions), by the method of immune fluorescence and PCR. The treatment provided positive influence on immune status (amount of CD4+; HLA-DR+ cell and IgA level normalized after the treatment). In 3 months after the treatment only 2 cases of Chlamydia trachomatis infection recurrence were registered. Treatment efficacy achieves 94.8 per cent.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000276:immunology; D002692:Chlamydia trachomatis; D004359:Drug Therapy, Combination; D052776:Female Urogenital Diseases / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D052801:Male Urogenital Diseases; D011994:Recombinant Proteins
chemical_list: D000900:Anti-Bacterial Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D017963:Azithromycin
vernacular_title: Kombinirovannoe lechenie persistiruiushcheĭ urogenital'noĭ khlamidiĭnoĭ infektsii sumamedom i interferonom-al'fa.