title: [The effect of melatonin on directional motility of human sperm under in vitro conditions].
abstract: In model experiments carried out in vitro, human spermatozoa move in well-ordered manner following the concentration gradient. Such behavior is called sperm chemotaxis. The investigations with use of melatonin indicate that this hormone, contained in the follicular liquid, cannot be regarded as chemotactic substance for human spermatozoa. Melatonin in concentrations of 1 mM and 10 mM respectively, do not influence the sperm behavior, however in concentration of 20 mM inhibits their movements in canals of incubation chamber, i.e. shows chemorepelent effect.
mesh_terms: D000328:Adult; D002633:Chemotaxis / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008550:Melatonin / Q000378:metabolism* / Q000494:pharmacology; D013081:Sperm Motility / Q000187:drug effects / Q000502:physiology*
chemical_list: D008550:Melatonin
vernacular_title: Wpływ melatoniny na kierunkowe przemieszczanie sie plemników człowieka w warunkach in vitro.