title: Manipulating large insert clones for transgenesis.
mesh_terms: D000818:Animals; D027042:Chromosomes, Artificial, P1 Bacteriophage / Q000235:genetics*; D018244:Chromosomes, Artificial, Yeast / Q000235:genetics*; D003001:Cloning, Molecular / Q000379:methods*; D005818:Genetic Engineering / Q000379:methods; D051379:Mice; D008822:Mice, Transgenic / Q000235:genetics*; D008845:Microinjections; D015183:Restriction Mapping; D019076:Transgenes / Q000235:genetics*