title: Calcium and bone metabolism during space flight.
abstract: Weightlessness induces bone loss. Understanding the nature of this loss and developing means to counteract it are significant challenges to potential human exploration missions. This article reviews the existing information from studies of bone and calcium metabolism conducted during space flight. It also highlights areas where nutrition may play a specific role in this bone loss, and where countermeasures may be developed to mitigate that loss.
mesh_terms: D015415:Biomarkers; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D004703:Endocrine System / Q000502:physiology; D006801:Humans; D013026:Space Flight; D014893:Weightlessness / Q000009:adverse effects*; D018544:Weightlessness Countermeasures
chemical_list: D015415:Biomarkers; D002118:Calcium
keywords: NASA Center JSC; NASA Discipline Regulatory Physiology