Retransplantation for recurrent hepatitis C.
1. Primary orthotopic liver transplantation (OLT) for hepatitis C is performed with good results. 2. Re-OLT in hepatitis C virus (HCV)-infected transplant recipients is performed mostly for indications other than recurrent disease in the short-term after primary OLT. 3. Progressive allograft injury and loss caused by recurrent disease predict an increased need for re-OLT for HCV recurrence in the long term. 4. Outcomes of re-OLT for recurrent hepatitis C are equivalent to results for other indications of re-OLT. 5. Good outcomes are obtained in selected patients when re-OLT is performed early in the course of recurrent disease before transplant recipients become critically ill.
D006084:Graft Rejection / Q000276:immunology; D006526:Hepatitis C / Q000276:immunology / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery / Q000821:virology; D016031:Liver Transplantation / Q000276:immunology; D012008:Recurrence; D012086:Reoperation; D016019:Survival Analysis; D016896:Treatment Outcome