Analysis and function of transcriptional regulatory elements: insights from Drosophila.
Analysis of gene expression is assuming an increasingly important role in elucidating the molecular basis of insect biology. Transcriptional regulation of gene expression is directed by a variety of cis-acting DNA elements that control spatial and temporal patterns of expression. This review summarizes current knowledge about properties of transcriptional regulatory elements, based largely on research in Drosophila melanogaster, and outlines ways that new technologies are providing tools to facilitate the study of transcriptional regulatory elements in other insects.
D000818:Animals; D030801:Animals, Genetically Modified; D005075:Biological Evolution; D019295:Computational Biology; D004247:DNA / Q000235:genetics; D004330:Drosophila / Q000235:genetics*; D004742:Enhancer Elements, Genetic; D017344:Genes, Insect; D023281:Genomics; D007313:Insecta / Q000235:genetics; D008297:Male; D008957:Models, Genetic; D010802:Phylogeny; D011401:Promoter Regions, Genetic; D014158:Transcription, Genetic
D004247:DNA