title: Wavefront-guided photorefractive keratectomy for myopia and myopic astigmatism.
abstract: OBJECTIVE
  To evaluate the results of wavefront-supported customized ablation (WASCA) in eyes treated with photorefractive keratectomy (PRK) to correct spherical myopia and myopic astigmatism.
  
  
  METHODS
  One-hundred fifty eyes of 104 patients (mean age 33.4 +/- 4.4 years) were included in the study. An Asclepion Shack-Hartmann wavefront aberrometer was used to assess lower and higher order refractive aberrations of eyes, and customized PRK treatments were carried out using the Asclepion-Meditec MEL 70 G-Scan excimer laser. Follow-up time was 6 months.
  
  
  RESULTS
  The mean preoperative spherical equivalent refraction was -4.02 +/- -1.04 D, and mean uncorrected visual acuity (UCVA) was 0.06 +/- 0.02. Postoperatively, mean UCVA was 1.04 (better than 20/20), mean best spectacle-corrected visual acuity was 1.22 (20/16), and average spherical equivalent refraction was -0.12 D; 98.6% (148 of 150 eyes) were within +/-0.50 D of intended refraction, and 100% were within +/-1.00 D. Concerning safety, in 71.1% of eyes (107 of 150) BSCVA was the same as preoperatively, and in 8.2% (11 of 150) it increased by two or more Snellen lines. None of the eyes lost two or more lines of BSCVA. The root mean square value for higher order aberrations increased 1.4 times following PRK.
  
  
  CONCLUSIONS
  WASCA-guided PRK was efficacious, safe and predictable; BSCVA may be improved by the WASCA method compared to results achievable with a traditional PRK technique, in spite of an increase in the root mean square value for higher-order aberrations.
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000601:surgery*; D003315:Cornea / Q000601:surgery*; D006801:Humans; D054018:Lasers, Excimer; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D018903:Photorefractive Keratectomy / Q000379:methods*; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014792:Visual Acuity; D014945:Wound Healing