title: Intracameral lidocaine in trabeculectomy. A preliminary safety and efficacy study.
abstract: OBJECTIVE
  To study the safety and efficacy of intracameral lidocaine as anaesthesia in trabeculectomy for primary open-angle glaucoma.
  
  
  METHODS
  Trabeculectomy under intracameral anaesthesia using 1% preservative-free lidocaine was performed in 10 patients with primary open-angle glaucoma. Intraoperative pain score, postoperative intraocular pressure (IOP) and endothelial cell count at 3 months were recorded.
  
  
  RESULTS
  The mean pain score was 1.70 +/- 1.34. The mean IOP was lowered from 24.60 +/- 8.28 mmHg preoperatively to 14.1 +/- 3.11 mm Hg postoperatively. There was no significant decrease in the mean endothelial cell count 3 months after the surgery (P = 0.375).
  
  
  CONCLUSIONS
  Intracameral lidocaine may be a safe and effective alternative anaesthesia method in trabeculectomy for uncomplicated primary open-angle glaucoma.
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D000867:Anterior Chamber / Q000601:surgery; D004341:Drug Evaluation; D005260:Female; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D007432:Intraoperative Period; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011446:Prospective Studies; D012449:Safety; D014130:Trabeculectomy; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine