A relationship between smell identification and empathy.
Olfaction is a sense that has close relationships with the limbic system and emotion. Empathy is a vicarious feeling of others' emotional states. The two functions are known to be subserved by common neuroanatomical structures, including orbitofrontal cortex, mediodorsal thalamus, and the amygdala. This study demonstrates a correlation between smell identification and empathy, using the Mehrabian and Epstein Empathy Questionnaire and Alberta Smell Test. Right nostril smell identification correlated with empathy, whereas the left nostril did not. Given the predominantly ipsilateral representation in the olfactory system, this is in accordance with right hemisphere dominance for emotional functions and empathy. Further, the emotional component of empathy (feeling another's emotions) correlated with smell, whereas a cognitive component (comprehending another's emotions) did not. This study is the first to demonstrate a relationship between empathy and smell in normal subjects, suggesting common neural substrates.
D000328:Adult; D000368:Aged; D000679:Amygdala / Q000502:physiology; D004645:Empathy; D006801:Humans; D008875:Middle Aged; D012903:Smell / Q000502:physiology*; D011795:Surveys and Questionnaires; D013788:Thalamus / Q000502:physiology