Sex differences in kidney mineral concentrations and urinary albumin excretion in rats given high-phosphorus feed.
We examined sex differences in kidney mineral concentrations and urinary albumin excretion in rats given feed containing various phosphorus (P) levels. With feed that was 0.6%, 0.9%, 1.2%, and 1.5% P, kidney calcium and P concentrations were higher in female rats than in male rats. With 1.2% or 1.5% P, urinary albumin excretion was higher in the female rats. The sex of the animal affected the kidney mineral concentrations and urinary albumin excretion in rats with a high P intake.
D000419:Albuminuria / Q000652:urine*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D003404:Creatinine / Q000097:blood / Q000652:urine; D004305:Dose-Response Relationship, Drug; D005260:Female; D007668:Kidney / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009397:Nephrocalcinosis / Q000209:etiology / Q000378:metabolism* / Q000652:urine; D016226:Phosphorus, Dietary / Q000008:administration & dosage / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar; D012737:Sex Factors
D016226:Phosphorus, Dietary; D003404:Creatinine; D002118:Calcium