Effect of extracellular fluid volume expansion on the interparabronchial septum of the avian lung.
Scanning electron microscopy was used to examine the interparabronchial septa of chickens as a potential site of lymphatic drainage in the avian lung. Anaesthetized chickens were subjected to extracellular fluid volume expansion to produce pulmonary oedema as a result of increased capillary fluid flux into the interstitial spaces of the lung. In normal (control) chickens, the adjacent parabronchi were separated by a minimal septal space. In the "volume-loaded" birds, however, the interparabronchial septal spaces were measurably thickened and engorged as a result of hydrostatic pulmonary oedema. These results, which were consistent with reports of the effect of hydrostatic pulmonary oedema in mammals, suggest that the interparabronchial septum is a potential route of lymphatic drainage in the avian lung.
D000818:Animals; D001980:Bronchi / Q000648:ultrastructure; D002645:Chickens; D005110:Extracellular Space; D015633:Extravascular Lung Water; D006874:Hydrostatic Pressure; D008168:Lung / Q000098:blood supply / Q000473:pathology / Q000503:physiopathology*; D008208:Lymphatic System / Q000648:ultrastructure; D008297:Male; D008855:Microscopy, Electron, Scanning; D011201:Poultry Diseases / Q000473:pathology*; D011654:Pulmonary Edema / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D014882:Water-Electrolyte Balance / Q000502:physiology*