title: Subcutaneous fat necrosis of the newborn presenting as a large plaque with lobulated cystic areas.
abstract: Subcutaneous fat necrosis of the newborn (SFN) usually occurs in the first few weeks of life in full-term infants and presents as indurated, distinct nodules with a predilection for the cheeks, shoulders, back, buttocks, and proximal extremities. Most cases are related to some form of fetal distress, including obstetric trauma. Some cases are associated with hypercalcemia. We report a case of SFN with an unusual clinical presentation, complicated by hypercalcemia.
mesh_terms: D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D004814:Epidermal Cyst / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D005218:Fat Necrosis / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D007150:Immunohistochemistry; D007231:Infant, Newborn; D018570:Risk Assessment; D012720:Severity of Illness Index; D012871:Skin Diseases / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy