Three novel cytochalasins X, Y, and Z from Pseudeurotium zonatum.
Fermentation of Pseudeurotium zonatum led to the isolation of the known cytochalasin G (1) and three new cytochalasins, X, Y, and Z (2-4). These four compounds are the only naturally occurring cytochalasins reported to date that contain an indole-substituted perhydroisoindol-1-one fused with an 11-membered macrocycle.
D001203:Ascomycota / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D003572:Cytochalasins / Q000737:chemistry* / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D009390:Nepal; D019906:Nuclear Magnetic Resonance, Biomolecular
D003572:Cytochalasins; C470238:cytochalasin X; C470239:cytochalasin Y; C470240:cytochalasin Z