title: Development of new pain management strategies.
abstract: The continued development of more effective and predictable methods for pain control is a process that combines the best efforts of basic and clinical scientists. This review explores the developing themes of clinical pain management strategies that are emerging from molecular, cellular, and physiologic research into pain mechanisms and emphasizes the unique opportunity that several years of well-controlled clinical trials affords the dental education community to provide evidence-based learning in pain treatment strategies.
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage; D000779:Anesthetics, Local / Q000008:administration & dosage; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002045:Bupivacaine / Q000008:administration & dosage; D019317:Evidence-Based Medicine; D005157:Facial Pain / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use; D007267:Injections; D009412:Nerve Fibers / Q000502:physiology; D009619:Nociceptors / Q000502:physiology; D010513:Periodontal Ligament; D017470:Receptors, Glutamate / Q000187:drug effects; D004561:Transcutaneous Electric Nerve Stimulation; D014275:Trigeminal Caudal Nucleus / Q000502:physiology
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal; D017470:Receptors, Glutamate; D007052:Ibuprofen; D002045:Bupivacaine