title: Wnt signalling: refocusing on Strabismus.
abstract: Vertebrate homologues of the Strabismus/van Gogh (stbm/vang) gene have been implicated in patterning and morphogenesis during gastrulation. Recent work shows that stbm/vang is mutated in zebrafish trilobite mutants and that stbm/vang is required for morphogenesis but not patterning during zebrafish gastrulation.
mesh_terms: D000818:Animals; D019521:Body Patterning; D004330:Drosophila / Q000196:embryology* / Q000235:genetics / Q000378:metabolism*; D029721:Drosophila Proteins; D005775:Gastrula / Q000166:cytology / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D009024:Morphogenesis; D010641:Phenotype; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D015398:Signal Transduction; D051153:Wnt Proteins; D015027:Zebrafish / Q000196:embryology* / Q000235:genetics / Q000378:metabolism*; D029961:Zebrafish Proteins
chemical_list: D029721:Drosophila Proteins; D008565:Membrane Proteins; D011518:Proto-Oncogene Proteins; C111638:Vang protein, Drosophila; D051153:Wnt Proteins; D029961:Zebrafish Proteins; C491759:vangl2 protein, zebrafish; C094522:wnt8b protein, zebrafish