title: F-18 FDG-positron emission tomographic scanning and Wegener's granulomatosis.
abstract: Wegener's granulomatosis is a necrotizing granulomatous vasculitis that mainly affects the upper airways, lungs, and kidneys. Autoimmune mechanisms are hypothesized to play a role in the pathophysiology of the disease. F-18 fluorodeoxyglucose-positron emission tomographic scanning is normally used to differentiate benign from malignant disease as a result of differences in glucose metabolism. The authors present a case of Wegener's granulomatosis in which F-18 fluorodeoxyglucose-positron emission tomographic scanning yielded a false-positive result.
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000378:metabolism; D000368:Aged; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D014890:Granulomatosis with Polyangiitis / Q000000981:diagnostic imaging* / Q000378:metabolism; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D011859:Radiography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D014055:Tomography, Emission-Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18