title: [Course of duodenal ulcer disease depending on personality type and effectiveness of differential psychotropic therapy].
abstract: OBJECTIVE
  To determine features of duodenal ulcer (DU) course as regards personality traits and to validate a differentiated approach to psychopharmacological correction of such patients.
  
  
  METHODS
  The personality type was determined in 102 DU patients using an experimental psychological examination.
  
  
  RESULTS
  Among the examinees, submissive and excitable personalities predominated (56.9 vs 43.1%, respectively). Submissive personalities were anxiously accentuated, moderately psychically rigid and moderately neurotic. Morphologically, they had diffuse fundal and antral gastritis with moderate H. pylori dissemination, intact acid production, ulcer size > 1 cm. Excitable personalities had antral gastritis with moderate H. pylori dissemination, high acid production, ulcer defect 0.6-0.9 cm.
  
  
  CONCLUSIONS
  Anti-acid and eradication therapy in combination with individual psychotropic therapy (amitriptilin in submissive and nozepam in excitable personalities) reduced the time of DU healing and prevent recurrence for one year.
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D010554:Personality Disorders / Q000188:drug therapy*; D011619:Psychotropic Drugs / Q000627:therapeutic use*
chemical_list: D011619:Psychotropic Drugs
vernacular_title: Techenie iazvennoĭ bolezni dvenadtsatiperstnoĭ kishki v zavisimosti ot tipa lichnosti i éffektivnost' differentsirovannoĭ psikhotropnoĭ terapii.