Characterization of human stellate cell activation-associated protein and its expression in human liver.
This study cloned cDNA of human homologue (hSTAP) of rat stellate cell activation-associated protein (rSTAP). hSTAP gene is on chromosome 17q and is composed of four exons. Various types of cells including hepatic stellate cells expressed hSTAP mRNA. Recombinant hSTAP was a heme protein with the activity of peroxidase. hSTAP can be used as a marker of quiescent stellate cells in human liver.
D000595:Amino Acid Sequence; D002886:Chromosomes, Human, Pair 17; D000078842:Cytoglobin; D018076:DNA, Complementary / Q000096:biosynthesis / Q000737:chemistry; D005091:Exons; D005914:Globins; D006420:Hemeproteins / Q000235:genetics*; D019693:Hepatitis, Autoimmune / Q000378:metabolism; D006525:Hepatitis, Viral, Human / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D008099:Liver / Q000378:metabolism*; D008969:Molecular Sequence Data; D010544:Peroxidases / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics*; D011994:Recombinant Proteins / Q000737:chemistry; D016415:Sequence Alignment
D000078842:Cytoglobin; D018076:DNA, Complementary; D006420:Hemeproteins; D011994:Recombinant Proteins; D005914:Globins; D010544:Peroxidases