title: Age-related changes in neocortical high-voltage spindles and alpha EEG power during quiet waking in rats.
abstract: Age-related changes in neocortical high-voltage spindle (HVS) and in electroencephalographic (EEG) alpha power were examined in young (3.0 to 4.6 months), middle-aged (10.2 to 13.8 months), and old (21.5 to 24.0 months) male Wistar rats during quiet waking. Whereas the duration of quiet waking stage did not change as a function of age, a significant increase in HVS amount and EEG alpha peak power was observed in the middle-aged rats with only a tendency for a further enhancement in the old animals. An additional analysis showed that the elevation of alpha power is associated with age rather than with HVS activity.
mesh_terms: D000375:Aging / Q000502:physiology*; D000513:Alpha Rhythm; D000818:Animals; D004569:Electroencephalography; D008297:Male; D019579:Neocortex / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D014851:Wakefulness / Q000502:physiology*