[The role of fetal echocardiography and genetic sonography in prenatal diagnosis of the Edward's syndrome--analysis of the thirty case diagnosed at the Department of the Diagnosis for Fetal Malformations at the Institute "Polish Mother's Memorial Hospital."].
OBJECTIVE
Trisomy 18 (Edward's syndrome) is one of the most common chromosomal aberration in fetuses/neonates. The aim of our study was to assess the usefulness of the fetal echocardiography and genetic sonography in prenatal diagnosis trisomy 18 (retrospective analysis).


METHODS
Between 1994-2000 at the Institute "Polish Mother's Memorial Hospital" 30 cases of trisomy 18 were diagnosed.


RESULTS
Every fetus/neonate presented with congenital anomalies. The most common were: intrauterine growth retardation (96%) and congenital heart defects (92%).


CONCLUSIONS
Retrospective analysis indicates the great role of "genetic sonography" and fetal echocardiography in prenatal diagnosis of trisomy 18.
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000235:genetics; D000328:Adult; D002887:Chromosomes, Human, Pair 18; D004452:Echocardiography; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies; D014314:Trisomy; D016216:Ultrasonography, Prenatal
Przydatność badania echokardiograficznego i poszerzonej sonografii w diagnostyce prenatalnej zespołu Edwardsa w materiale Zakładu Diagnostyki Wad Wrodzonych ICZMP (analiza 30 przypadkow).