S cone contributions to the magnocellular visual pathway in macaque monkey.
The magnocellular visual pathway is believed to receive input from long (L) and middle (M), but not short (S), wavelength-sensitive cones. Recording from neurons in magnocellular layers of lateral geniculate nucleus (LGN) in macaque monkeys, we found that magnocellular neurons were unequivocally responsive to S cone-isolating stimuli. A quantitative analysis suggests that S cones provided about 10% of the input to these cells, on average, while L:M ratios were far more variable. S cone signals influenced responses with the same sign as L and M cone inputs (i.e., no color opponency). Magnocellular afferent recordings following inactivation of primary visual cortex demonstrated that S cone signals were feedforward in nature and did not arise from cortical feedback to LGN
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D003118:Color Perception / Q000502:physiology*; D005829:Geniculate Bodies / Q000166:cytology / Q000502:physiology*; D008253:Macaca mulatta / Q000033:anatomy & histology / Q000502:physiology*; D008255:Macaca radiata / Q000033:anatomy & histology / Q000502:physiology*; D010775:Photic Stimulation; D017949:Retinal Cone Photoreceptor Cells / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology; D014795:Visual Pathways / Q000166:cytology / Q000502:physiology*