title: Clinical efficacy of teflubenzuron (Calicide) for the treatment of Lepeophtheirus salmonis infestations of farmed Atlantic salmon Salmo salar at low water temperatures.
abstract: The efficacy of teflubenzuron (Calicide) for the treatment of farmed Atlantic salmon Salmo salar L. infested with sea lice Lepeophtheirus salmonis (Krøyer, 1838), was investigated at low water temperatures in 2 commercial salmon farms. Calicide, coated on commercial feed pellets, was administered orally at 10 mg kg(-1) d(-1) for 7 consecutive days. Fish were randomly sampled and lice numbers recorded from both treated and control groups on 3 or 4 sampling occasions post-medication. Statistically significant reductions in the number of L. salmonis per fish were recorded. Maximum efficacy was observed toward chalimus and preadult stages of L. salmonis, and was achieved approximately 26 d post-medication. No adverse drug reactions or palatability problems were associated with the treatments.
mesh_terms: D000818:Animals; D001549:Benzamides / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D033342:Copepoda; D004478:Ectoparasitic Infestations / Q000188:drug therapy / Q000662:veterinary*; D005393:Fish Diseases / Q000188:drug therapy* / Q000469:parasitology; D005398:Fisheries; D007605:Juvenile Hormones / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D020317:Salmo salar / Q000469:parasitology*; D013696:Temperature; D016896:Treatment Outcome
chemical_list: D001549:Benzamides; D007605:Juvenile Hormones; C052595:teflubenzuron