title: Inhibition of fluid phase and clot-bound thrombin by the thrombin exosite I ligand LU 58463: comparison with heparin and hirudin.
mesh_terms: D002122:Calcium Chloride / Q000494:pharmacology; D020134:Catalytic Domain; D004305:Dose-Response Relationship, Drug; D006493:Heparin / Q000737:chemistry*; D006629:Hirudins / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D010446:Peptide Fragments / Q000627:therapeutic use*; D017434:Protein Structure, Tertiary; D013696:Temperature; D013917:Thrombin / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D013997:Time Factors
chemical_list: D006629:Hirudins; C470174:LU 58463; D008024:Ligands; D010446:Peptide Fragments; D006493:Heparin; D013917:Thrombin; D002122:Calcium Chloride