Drug reaction to ursodeoxycholic acid: lichenoid drug eruption in an infant using ursodeoxycholic acid for neonatal hepatitis.
Lichenoid drug eruptions are skin reactions associated with a number of drugs and chemicals. They are rare in infants. We report here an infant who presented with neonatal hepatitis and who was being treated with ursodeoxycholic acid. The infant developed lichenoid skin eruptions in the third week of the therapy. The lesions have resolved two months after the discontinuation of the drug. To our knowledge, this is the first infant case of lichenoid drug eruption associated with ursodeoxycholic acid.
D002756:Cholagogues and Choleretics / Q000009:adverse effects*; D006505:Hepatitis / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D017512:Lichenoid Eruptions / Q000209:etiology*; D008297:Male; D014580:Ursodeoxycholic Acid / Q000009:adverse effects*
D002756:Cholagogues and Choleretics; D014580:Ursodeoxycholic Acid