title: Polypharmacy and dentistry: I. Introduction and interactions with local anaesthetics and sedative drugs.
abstract: This series of two papers considers the effects of drug interactions in dentistry. In this first paper, the principles of drug interactions will be described. In addition, interactions with drugs used in local anaesthesia and sedation will be discussed. The second paper will concentrate on interactions with analgesics and antimicrobials prescribed in dental practice.
mesh_terms: D000766:Anesthesia, Dental; D000779:Anesthetics, Local / Q000494:pharmacology*; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001569:Benzodiazepines; D004347:Drug Interactions; D006801:Humans; D019338:Polypharmacy; D014662:Vasoconstrictor Agents / Q000494:pharmacology*
chemical_list: D000779:Anesthetics, Local; D014151:Anti-Anxiety Agents; D014662:Vasoconstrictor Agents; D001569:Benzodiazepines