Water-soluble oligomer dimers based on paracyclophane: a new optical platform for fluorescent sensor applications.
Water soluble paracyclophane chromophore dimers provide optical reporters that show little sensitivity to surfactants and thus are ideal for biosensor design. Strong intramolecular delocalization circumvents complications from intermolecular delocalization in spontaneously formed aggregates. The synthesis of 2 involves a novel TBAT deprotection/butane sultone ring-opening sequence, which should be general for the preparation of water-soluble conjugated oligomers and polymers.
D015374:Biosensing Techniques / Q000379:methods*; D001952:Bridged-Ring Compounds / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008027:Light; D011108:Polymers / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D012542:Scattering, Radiation; D012995:Solubility; D013050:Spectrometry, Fluorescence / Q000379:methods; D013501:Surface-Active Agents / Q000737:chemistry; D014867:Water / Q000737:chemistry
D001952:Bridged-Ring Compounds; D004987:Ethers; D005456:Fluorescent Dyes; D011108:Polymers; D000644:Quaternary Ammonium Compounds; D013501:Surface-Active Agents; D014867:Water; C022806:dodecyltrimethylammonium