title: Palladium-catalyzed cycloalkylations of 2-bromo-1,n-dienes with organoboronic acids.
abstract: Cascade palladium-catalyzed cycloalkylations of 2-bromo-1,n-dienes were accomplished in good to excellent yields, where the alkylpalladium intermediates, formed via an intramolecular Heck reaction of 2-bromo-1,n-dienes (n = 6 or 7), were successfully cross-coupled with various organoboronic acids. The optimal yields were achieved by the use of cesium carbonate in ethanol with Pd(PPh(3))(4) as catalyst, with 2-bromo-1,n-dienes and organoboronic acids at concentrations of 0.2 and 0.3 M (1.5 equiv), respectively.