title: Extinction of the soleus H reflex induced by conditioning stimulus given after test stimulus.
abstract: OBJECTIVE
  To quantify the extinction of the soleus H reflex induced by a conditioning stimulus above the motor threshold to the post-tibial nerve applied 10-12 ms after a test stimulus (S2 method).
  
  
  METHODS
  Ten healthy subjects participated. The sizes of extinction induced by a test stimulus above the motor threshold (conventional method) and by the S2 method were measured.
  
  
  RESULTS
  The size of the conditioned H reflex decreased as the intensity of the S2 conditioning stimulus increased. The decrease was less than that induced by the conventional method. The difference between the two methods correlated highly with the amount of orthodromically activated recurrent inhibition. When the S2 conditioning stimulus evoked an M wave that was roughly half of the maximum M wave, the decrease in the size of the conditioned H reflex depended on the size of the unconditioned H reflex.
  
  
  CONCLUSIONS
  The S2 method allows us to observe extinction without changing the intensity of the test stimulus. The amount of the extinction depends partially on the size of the unconditioned H reflex. The difference in the sizes of extinction between the S2 and conventional methods should relate to recurrent inhibition.
mesh_terms: D000293:Adolescent; D000328:Adult; D003213:Conditioning, Psychological / Q000502:physiology*; D004576:Electromyography; D005108:Extinction, Psychological; D006181:H-Reflex / Q000502:physiology*; D006801:Humans; D018482:Muscle, Skeletal / Q000502:physiology*; D009433:Neural Inhibition / Q000502:physiology