Effects of adaptogens on granulocytopoiesis during paradoxical sleep deprivation.
We studied the effects of extracts from Siberian ginseng, Rhodiola rosea, bergenia, and ginseng (G115) and pantohematogen on granulocytopoiesis after paradoxical sleep deprivation. The effects of adaptogens on the blood system were most pronounced during hyperplasia of granulocytopoiesis. Natural preparations were divided into groups depending on their activity. Extracts of Siberian ginseng and Rhodiola rosea did not modulate granulocytopoiesis. Ginseng G115 extract suppressed granulocytopoiesis. Bergenia extract and pantohematogen produced ambiguous effects on the granulocytic hemopoietic stem.
D000485:Allergens / Q000737:chemistry; D001685:Biological Factors; D006098:Granulocytes / Q000166:cytology / Q000187:drug effects*; D006801:Humans; D019684:Magnoliopsida / Q000737:chemistry; D005894:Panax / Q000737:chemistry / Q000145:classification; D010936:Plant Extracts / Q000494:pharmacology*; D029771:Rhodiola / Q000737:chemistry; D012892:Sleep Deprivation / Q000473:pathology*
D000485:Allergens; D001685:Biological Factors; D010936:Plant Extracts; C404022:pantohematogen