title: Chronic obstructive pulmonary disease * 3: Experimental animal models of pulmonary emphysema.
abstract: The use of genetically manipulated mice together with traditional animal studies are steadily increasing our knowledge of the factors important in determining alveolar formation and destruction in emphysema. A review of the animal models used to study emphysema is presented.
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D018390:Gene Targeting; D005818:Genetic Engineering; D051379:Mice; D008817:Mice, Mutant Strains; D008822:Mice, Transgenic; D009154:Mutation / Q000235:genetics; D029424:Pulmonary Disease, Chronic Obstructive / Q000209:etiology*; D011656:Pulmonary Emphysema / Q000139:chemically induced / Q000209:etiology*