[Instrumental evaluation of sensory thresholds in subjects with different pain sensitivity].
Will the aid of a modified apparatus the authors determined the sensory thresholds of tactile, and pain sensitivity, and the limit of pain tolerance. Subject to measurement were 500 persons. By the nature of the initial high sensitivity (minor thresholds), moderate (medium) and low (major thresholds) ones. The effect of taking by mouth metherasine (0.025) and amidopyrine with analgin (0.25 each) was analyzed in each group. It was ascertained that the mechanism of their action, produced the greatest effect in persons with an initially elevated sensitivity to pain stimulators. Metherasine changed to a greater extent the pain tolerance thresholds, whereas amidopyrin with analgin did the same with the pain thresholds. In individuals with an initially elevated pain sensitivity both the pain threshold and that or the pain tolerance were higher. These date are of importance for rational approach to an individual choice of substances to be prescribed with a different attitude to pain.
Larentsova
L I
LI
Maksimovskiĭ
Iu M
IuM
Polunocheva
I V
IV
D000293:Adolescent; D000328:Adult; D000368:Aged; D000632:Aminopyrine / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D004177:Dipyrone / Q000494:pharmacology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000150:complications; D010147:Pain Measurement / Q000295:instrumentation*; D017288:Pain Threshold / Q000187:drug effects* / Q000502:physiology / Q000523:psychology; D011229:Preanesthetic Medication
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000632:Aminopyrine; D004177:Dipyrone