title: [Effects of Buyanghuanwu decoction (BYHWT) on proliferation of cultured rat cortical neurons].
abstract: OBJECTIVE
  To observe the effect of rat serum containing Buyanghuanwu decoction (BYHWT) on the proliferation of cultured rat cortical neurons, so as to understand the mechanism of BYHWT in the treatment of hypoxia brain damage.
  
  
  METHODS
  The growth of cultured rat cortical neurons were observed by MTT assay to evaluate the effect of the serum containing BYHWT on the neurons cultured in both normal and hypoxia conditions.
  
  
  RESULTS
  BYHWT significantly promoted proliferation of the neurons cultured under both normal and hypoxia conditions, in comparison with the response of the cells to drug-free serum (P<0.05).
  
  
  CONCLUSIONS
  Some of the constituents of BYHWT in rat serum can promote the proliferation of rat cortical neurons cultured in both normal and hypoxia conditions.
authors.affiliation: Department of Traditional Chinese Medicine, First Military Medical University, Guangzhou 510515, China.
authors.forename: Li
authors.initials: L
authors.lastname: Tong
authors.forename: Hong-Da
authors.initials: HD
authors.lastname: Qu
authors.forename: Yu-Yao
authors.initials: YY
authors.lastname: Chen
authors.forename: Jian-Gang
authors.initials: JG
authors.lastname: Shen
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D015687:Cell Hypoxia; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008297:Male; D009474:Neurons / Q000166:cytology / Q000187:drug effects*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004365:Drugs, Chinese Herbal; C460102:buyang huanwu