title: Efficacy of selamectin in the treatment of naturally acquired cheyletiellosis in cats.
abstract: The purpose of this study was to evaluate the efficacy of a topical formulation of selamectin in the treatment of cheyletiellosis in cats. Fifteen adult domestic cats from the same household with naturally occurring Cheyletiella sp. infestation were enrolled in the study. On each cat, 45 mg of selamectin was applied on days 0, 30, and 60. No other treatment or environmental decontamination was performed during the trial. On days 0, 30, 60, and 120, all cats were examined, epidermal debris was collected over the dorsal area of the body with flea combs for microscopic examination, and fecal flotations were done. Clinical signs had subsided by day 60 in all 15 cats and no signs of recurrence were apparent on follow-up 1 year later. All epidermal and fecal samples were negative by day 60. No adverse reactions were observed. Under the conditions of our study, topical selamectin was a practical and well-tolerated means of treatment for cheyletiellosis in cats.
authors.affiliation: Département de sciences cliniques, Faculté de médecine vétérinaire, Université de Montréal, CP 5000, St-Hyacinthe, Québec J2S 7C6.
authors.forename: Nadège
authors.initials: N
authors.lastname: Chailleux
authors.forename: Manon
authors.initials: M
authors.lastname: Paradis
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use*; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D005243:Feces / Q000469:parasitology; D005260:Female; D006197:Hair / Q000469:parasitology; D006801:Humans; D007559:Ivermectin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D008297:Male; D008924:Mite Infestations / Q000188:drug therapy / Q000662:veterinary*; D008925:Mites / Q000254:growth & development; D012867:Skin / Q000469:parasitology; D013997:Time Factors; D016896:Treatment Outcome; D015047:Zoonoses
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin; C414354:selamectin