Two-step electrochemical annulation for the assembly of polycyclic systems.
[reaction: see text] A two-step electrochemical annulation has been developed for the preparation of fused furans. The process involves an initial conjugate addition of a furyethyl cuprate and trapping of the enolate as the corresponding silyl enolether. The second step of the annulation involves the anodic coupling of the furan and the silyl enol ether to form a six-membered ring.
Whitehead
Christopher R
CR
Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA.
Sessions
E Hampton
EH
Ghiviriga
Ion
I
Wright
Dennis L
DL