title: Bioabsorbable anterior lumbar plate fixation in conjunction with anterior interbody fusion cages.
abstract: An in vitro biomechanical study was conducted to determine the effects of anterior stabilization on lumbar interbody cage fusion biomechanics in a multilevel human cadaveric lumbar model. Three spine conditions were compared: harvested, bilateral multilevel cages (CAGES), and CAGES with bioabsorbable anterior plates (CBAP), tested under flexion/extension, lateral bending, and axial rotation. Measurements included vertebral motion, applied load, and bending/rotational moments. Application of anterior fixation decreased local motion and increased stiffness of the instrumented levels. Clinically, this spinal stability may serve to promote fusion. Coupled with the bioabsorbability of the plating material, the bioabsorbable anterior lumbar plating system is considered biomechanically advantageous.
authors.affiliation: School of Biomedical Engineering, The University of Tennessee Health Science Center, Memphis, USA.
authors.forename: Denis J
authors.initials: DJ
authors.lastname: DiAngelo
authors.forename: Scott
authors.initials: S
authors.lastname: Kitchel
authors.forename: Bobby J
authors.initials: BJ
authors.lastname: McVay
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Scifert
authors.forename: G Bryan
authors.initials: GB
authors.lastname: Cornwall
mesh_terms: D020341:Absorbable Implants; D000368:Aged; D000704:Analysis of Variance; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D001860:Bone Plates; D002102:Cadaver; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011336:Probability; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D012399:Rotation; D012680:Sensitivity and Specificity; D013123:Spinal Fusion / Q000295:instrumentation*; D013314:Stress, Mechanical; D013718:Tensile Strength; D016474:Weight-Bearing
chemical_list: D001672:Biocompatible Materials