title: Positron emission tomography, echo-doppler, and exercise studies of functional capacity in hypertensive heart disease.
abstract: BACKGROUND
  This study examines the relationship between functional capacity, left ventricular diastolic function, and myocardial perfusion reserve (MPR) in patients with left ventricular hypertrophy (LVH).
  
  
  METHODS
  We studied 16 patients with LVH and 10 controls. Functional capacity was assessed by cardiopulmonary exercise, MPR by positron emission tomography, and left ventricular diastolic function by echo-Doppler.
  
  
  RESULTS
  Functional capacity and MPR were significantly lower in the patients. Functional capacity correlated positively with MPR and left ventricular diastolic function.
  
  
  CONCLUSIONS
  Diminished functional capacity in patients with hypertension-induced LVH is related to the impairment in MPR and left ventricular diastolic function.
authors.affiliation: Non-Invasive Laboratory, St. Francis Hospital, Roslyn, State University of New York at Stony Brook, USA. ooa2@columbia.edu
authors.forename: Olakunle O
authors.initials: OO
authors.lastname: Akinboboye
authors.forename: Olajide
authors.initials: O
authors.lastname: Idris
authors.forename: Rochelle
authors.initials: R
authors.lastname: Goldsmith
authors.forename: Kati
authors.initials: K
authors.lastname: Berekashvili
authors.forename: Ru-Ling
authors.initials: RL
authors.lastname: Chou
authors.forename: Steven R
authors.initials: SR
authors.lastname: Bergman
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003971:Diastole; D015150:Echocardiography, Doppler; D005080:Exercise Test; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D014055:Tomography, Emission-Computed; D014655:Vascular Resistance