title: (31)phosphorous and single voxel proton MR spectroscopy and diffusion-weighted imaging in a case of star fruit poisoning.
abstract: We herein describe the case of a patient with chronic renal failure complicated by star fruit poisoning. T2-weighted and diffusion-weighted MR imaging showed hyperintense lesions at the thalami and right temporo-occipital cortex. Single voxel proton MR spectroscopy revealed elevation of lactate and (31)phosphorous MR spectroscopy revealed elevation of inorganic phosphate and decrease of phosphocreatine and nucleoside triphosphates. The imaging and metabolic changes indicated energy deprivation, with subsequent cortical necrosis proved at autopsy.
authors.affiliation: Departments of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
authors.forename: Y L
authors.initials: YL
authors.lastname: Chan
authors.forename: H K
authors.initials: HK
authors.lastname: Ng
authors.forename: C B
authors.initials: CB
authors.lastname: Leung
authors.forename: D K W
authors.initials: DK
authors.lastname: Yeung
mesh_terms: D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000032:analysis; D001921:Brain / Q000473:pathology*; D001923:Brain Chemistry; D038524:Diffusion Magnetic Resonance Imaging; D005638:Fruit / Q000506:poisoning*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy; D019344:Lactic Acid / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D009711:Nucleotides / Q000032:analysis; D010710:Phosphates / Q000032:analysis; D010725:Phosphocreatine / Q000032:analysis; D006435:Renal Dialysis
chemical_list: D009711:Nucleotides; D010710:Phosphates; D010725:Phosphocreatine; D001224:Aspartic Acid; D019344:Lactic Acid; C000179:N-acetylaspartate