Lymphocytic hypophysitis mimicking pituitary macroadenoma.
Lymphocytic hypophysitis is an uncommon disease with a variable presentation and unclear pathophysiology. We present the case of a 30 year old woman who presented with features typical of a pituitary macroadenoma. She underwent a transphenoidal resection of the mass and histopathological examination revealed lymphocytic hypophysitis. This case illustrates the difficulty in differentiating pituitary macroadenoma and lymphocytic hypophysitis and the variable presentations of lymphocytic hypophysitis.
Skandarajah
Anita
A
Department of Neurosurgery, Royal Melbourne Hospital, University of Melbourne, Grattan Street, Parkville, Australia.
Ng
Wai Hoe
WH
Gonzales
Michael
M
Kaye
Andrew H
AH
D000236:Adenoma / Q000175:diagnosis / Q000473:pathology*; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D017252:CD3 Complex / Q000276:immunology; D003348:Cortisone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010900:Pituitary Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D013601:T-Lymphocytes / Q000473:pathology; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D017252:CD3 Complex; D003348:Cortisone