Black cohosh and other herbal remedies associated with acute hepatitis.
Six patients presented with clinical, biochemical and histological evidence of severe hepatitis after taking herbal remedies. One patient required urgent liver transplantation for fulminant hepatic failure after the brief use of black cohosh. Five patients took a combination of herbs and presented with jaundice, fatigue and pruritus. Healthcare providers and members of the public should be aware of the potential adverse effects of these remedies.
Whiting
Peter W
PW
Princess Alexandra Hospital, Woolloongabba, QLD, Australia.
Clouston
Andrew
A
Kerlin
Paul
P
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D031885:Cimicifuga / Q000009:adverse effects*; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D028321:Plant Preparations / Q000009:adverse effects*; D011241:Prednisone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D028321:Plant Preparations; D011241:Prednisone