Pseudomalignant spindle cell proliferation of the urinary bladder: an unusual cause of voiding symptoms in a young patient.
A case of an unusually large pseudomalignant spindle-cell proliferation (or inflammatory pseudotumor) of the urinary bladder in a young man is presented. The only symptom was urinary frequency. The clinical and radiologic evaluation (ultrasonography, computed tomography, and magnetic resonance imaging) revealed a massive tumor (11 x 7.5 x 5.5 cm) arising from the bladder wall that was eventually resected without compromising bladder function. Although the histologic findings initially suggested a sarcoma, the immunohistochemical findings were consistent with that of an inflammatory pseudotumor. The patient remained asymptomatic, without evidence of recurrence, after 12 months of follow-up. Awareness of this inflammatory pseudotumor and its immunophenotypic characteristics is important to avoid an erroneous diagnosis and unnecessarily aggressive therapy.
Gyftopoulos
K
K
Department of Urology, 401 General Armed Forces Hospital, Athens, Greece.
Serafetinidis
E
E
Sambaziotis
D
D
Archondakis
A
A
D000328:Adult; D003937:Diagnosis, Differential; D006104:Granuloma, Plasma Cell / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D012509:Sarcoma / Q000175:diagnosis; D014463:Ultrasonography; D001743:Urinary Bladder / Q000473:pathology; D001745:Urinary Bladder Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis; D014555:Urination Disorders / Q000175:diagnosis / Q000209:etiology*