title: Case discussion: impaired renal function and tolerance to high altitude.
abstract: A 58-year-old woman who plans a trek in the Himalayas at altitudes from 4500 to 5000 m is known to have the loss of about 50% of renal function based on glomerular filtration studies and renal biopsy. Possible risks and management are discussed.
mesh_terms: D000064:Acclimatization / Q000502:physiology*; D000086:Acetazolamide / Q000008:administration & dosage*; D000531:Altitude; D000532:Altitude Sickness / Q000150:complications*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis*; D007674:Kidney Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D007677:Kidney Function Tests; D008875:Middle Aged; D009051:Mountaineering / Q000502:physiology; D011379:Prognosis; D012079:Renal Circulation; D018570:Risk Assessment
chemical_list: D000086:Acetazolamide