A general and straightforward route toward diarylmethanes. Integrated cross-coupling reactions using (2-pyridyl)silylmethylstannane as an air-stable, storable, and versatile coupling platform.
[reaction: see text] Pharmacologically important diarylmethane structures have been prepared in a straightforward manner through sequentially integrated Pd-catalyzed cross-coupling reactions. (2-Pyridyl)silylmethylstannane was found to be an air-stable, storable, and versatile coupling platform in this synthetic strategy.
Itami
Kenichiro
K
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Kyoto 606-8501, Japan.
Mineno
Masahiro
M
Kamei
Toshiyuki
T
Yoshida
Jun-Ichi
J