title: Myringoplasty: does the size of the perforation matter?
abstract: Does the size of a tympanic membrane defect influence the success rate in myringoplasty? Many studies which have suggested that size does not affect results have included only small numbers of patients. After a power analysis to identify the size of groups needed to detect a clinically significant difference between the success rate of small and large perforations, a retrospective study was carried out to answer the question. A retrospective study of 423 myringoplasty-only operations showed that size does influence success; the success rate for small perforations was 74.1% compared with 56.0% for large perforations (P = 0.0003). Size also influences the change in four-frequency air conduction thresholds (small perforations +7.2 dB, large perforations +10.2 dB; t = 2.08, P = 0.039) in successful myringoplasties, a positive value indicating an improvement in hearing. This change is unlikely to be clinically significant. Patients should be made aware of these facts when informed consent is being obtained.
authors.affiliation: The Department of Otolaryngology, The Royal Infirmary of Edinburgh, Edinburgh, UK.
authors.forename: P
authors.initials: P
authors.lastname: Lee
authors.forename: G
authors.initials: G
authors.lastname: Kelly
authors.forename: R P
authors.initials: RP
authors.lastname: Mills
mesh_terms: D001299:Audiometry; D001309:Auditory Threshold; D006801:Humans; D009225:Myringoplasty; D012044:Regression Analysis; D012189:Retrospective Studies; D016896:Treatment Outcome; D018058:Tympanic Membrane Perforation / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*