title: Needle-knife sphincterotomy.
abstract: Choledochocele, now classified as choledochal cyst type III, is a rare anomaly of the terminal biliary tree causing abdominal pain, pancreatitis, and obstructive cholestasis. Traditionally, the therapy for this malformation has been surgery. Recently, endoscopic therapy has been used alternatively for the treatment of choledochocele mainly in adults. We report two patients with recurrent episodes of acute pancreatitis found to be caused by a large choledochocele; both patients were treated by needle-knife sphincterotomy without complications. They remained asymptomatic at 1 and 2 years' follow-up, respectively. Despite the fact that the risk of bleeding seems to be higher using needle-knife sphincterotomy, when the Choledochocele is large, our experience suggests that needle-knife sphincterotomy can be performed accurately and safely. Further studies are necessary to confirm the safety and effectiveness of needle-knife sphincterotomy in large choledochocles.
authors.affiliation: Department of Endoscopy and Motility Unit, Central Hospital, Ethnikis Aminis 41, TT 54635 Thessaloniki, Greece. pantso@the.forthnet.gr
authors.forename: P
authors.initials: P
authors.lastname: Katsinelos
authors.forename: S
authors.initials: S
authors.lastname: Dimiropoulos
authors.forename: I
authors.initials: I
authors.lastname: Galanis
authors.forename: I
authors.initials: I
authors.lastname: Pilpilidis
authors.forename: P
authors.initials: P
authors.lastname: Amperiadis
authors.forename: D
authors.initials: D
authors.lastname: Katsiba
authors.forename: P
authors.initials: P
authors.lastname: Tsolkas
authors.forename: B
authors.initials: B
authors.lastname: Papaziogas
authors.forename: G
authors.initials: G
authors.lastname: Paroutoglou
authors.forename: A
authors.initials: A
authors.lastname: Papagiannis
authors.forename: I
authors.initials: I
authors.lastname: Vasiliadis
mesh_terms: D000208:Acute Disease; D000368:Aged; D015529:Choledochal Cyst / Q000150:complications / Q000601:surgery*; D004108:Dilatation, Pathologic / Q000150:complications / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010195:Pancreatitis / Q000209:etiology; D012008:Recurrence; D016717:Sphincterotomy, Endoscopic / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome