title: Small animal imaging. current technology and perspectives for oncological imaging.
abstract: Advances in the biomedical sciences have been accelerated by the introduction of many new imaging technologies in recent years. With animal models widely used in the basic and pre-clinical sciences, finding ways to conduct animal experiments more accurately and efficiently becomes a key factor in the success and timeliness of research. Non-invasive imaging technologies prove to be extremely valuable tools in performing such studies and have created the recent surge in small animal imaging. This review is focused on three modalities, PET, MR and optical imaging which are available to the scientist for oncological investigations in animals.
authors.affiliation: Radiation Sciences, Washington University School of Medicine, Saint Louis, MO, USA.
authors.forename: Jason S
authors.initials: JS
authors.lastname: Lewis
authors.forename: S
authors.initials: S
authors.lastname: Achilefu
authors.forename: J R
authors.initials: JR
authors.lastname: Garbow
authors.forename: R
authors.initials: R
authors.lastname: Laforest
authors.forename: M J
authors.initials: MJ
authors.lastname: Welch
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D003952:Diagnostic Imaging / Q000379:methods*; D015870:Gene Expression; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics; D019275:Radiopharmaceuticals / Q000378:metabolism; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals