InCl(3)-catalyzed three-component asymmetric Mannich-type reaction in methanol.
[reaction: see text] A one-pot InCl(3)-catalyzed Mannich-type reaction was carried out in methanol. High diastereoselectivities and high yields were obtained. In addition, after the reaction was completed, InCl(3) can be recycled and reused without a drop of activity and selectivity.
Loh
Teck-Peng
TP
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, USA.
Chen
Shui-Ling
SL