C-reactive protein should accelerate the diagnosis of bowel injury after gynecologic surgery.
OBJECTIVE
To search for a marker that could aid in earlier diagnosis of bowel injury after gynecologic surgery.


METHODS
Retrospective case study with prospective controls (Canadian Task Force classification II-2).


METHODS
University hospital.


METHODS
Fourteen women with bowel injuries and 50 controls with no postoperative complications.


RESULTS
Bowel injury occurred in 14 (2.4/1000) of 5901 gynecologic procedures. Of these, eight were recognized intraoperatively and treated immediately. In six women C-reactive protein levels were markedly increased (>100 mg/L) relative to control patients (p <0.0001).


CONCLUSIONS
Systematic postoperative assessment of C-reactive protein in patients at high risk for bowel injury may help identify this complication earlier in the postoperative period.
Rongières
C
C
Department of Obstetrics and Gynecology, Hospital Antoine Beclere, Clamart, France.
Gomel
V
V
Garbin
O
O
Fernandez
H
H
Frydman
R
R
D000328:Adult; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis* / Q000209:etiology; D007422:Intestines / Q000293:injuries*; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods; D007813:Laparotomy / Q000009:adverse effects / Q000379:methods; D008875:Middle Aged; D011183:Postoperative Complications / Q000097:blood / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011336:Probability; D011446:Prospective Studies; D012016:Reference Values; D012086:Reoperation; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013997:Time Factors
D015415:Biomarkers; D002097:C-Reactive Protein