Severe megacystis and bilateral hydronephrosis in a female fetus.
The differential diagnosis for antenatal bladder dilation and hydronephrosis is extensive, ranging from posterior urethral valves to neurogenic bladder. We present a case of a female fetus diagnosed antenatally with severe megacystis and bilateral hydroureteronephrosis. The patient was found to have megacystis-microcolon-intestinal hypoperistalsis syndrome, a rare, congenital, and generally fatal disorder in which there is functional obstruction of the bladder and intestine.
Bloom
Tammy L K
TL
Department of Urology, Naval Medical Center San Diego, San Diego, California 92134, USA.
Kolon
Thomas F
TF
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D000328:Adult; D003106:Colon / Q000002:abnormalities* / Q000000981:diagnostic imaging; D004108:Dilatation, Pathologic / Q000151:congenital / Q000000981:diagnostic imaging; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging*; D006801:Humans; D006869:Hydronephrosis / Q000151:congenital / Q000000981:diagnostic imaging*; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000151:congenital / Q000000981:diagnostic imaging; D011247:Pregnancy; D013577:Syndrome; D016216:Ultrasonography, Prenatal; D001743:Urinary Bladder / Q000002:abnormalities* / Q000000981:diagnostic imaging; D001745:Urinary Bladder Diseases / Q000151:congenital / Q000000981:diagnostic imaging