Cytosolic calcium oscillations in signal transduction pathways.
The oscillatory nature of the intracellular calcium signal has been recognized as soon as the methodological developments allowed us to record calcium fluctuations at the single cell level. While the principal mechanisms responsible for the generation of these oscillations have been partially resolved, more attention has been recently focused on signal decoding and more particularly on the role of cell structure organization in transducing this signal to the molecular targets of the calcium messenger.
Rossier
Michel F
MF
Division of Endocrinology Diabetology, Department of Internal Medicine, University Hospital, CH-1211 Geneva 14, Switzerland. rossier@cmu.unige.ch
Capponi
Alessandro M
AM
D000818:Animals; D020013:Calcium Signaling / Q000502:physiology*; D003600:Cytosol / Q000502:physiology; D015195:Drug Design; D025461:Feedback, Physiological; D006801:Humans; D008928:Mitochondria / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology