title: Prevalence of latex sensitization in health care workers of a general hospital in Palermo, Sicily.
abstract: OBJECTIVE
  To assess the prevalence of latex sensitization in a group of hospital employees in a general hospital.
  
  
  METHODS
  Cross-sectional study on hypersensitivity to latex gloves among health-care workers.
  
  
  METHODS
  A general hospital in Palermo, Sicily.
  
  
  METHODS
  196 health-care workers answered a questionnaire about their case history of allergic diseases (i. e., rhinitis and/or asthma) and about symptoms after wearing latex gloves. All subjects were tested by skin prick test (SPT) with commercial latex extract and aeroallergens and had blood draw for total serum IgE and latex-specific IgE testing and glove-use test.
  
  
  RESULTS
  42% of the subjects who answered the questionnaire reported at least one symptom after wearing latex gloves. All symptoms were local, and none of the subjects reported systemic reactions. The most common symptom was itching, but none of subjects with only itching presented a positive SPT or specific serum IgE to latex. The SPT to latex was positive in 19 of 196 subjects (9.7%). Specific IgE to latex were found in 15/196 subjects (7.6%). Glove-use test was positive in 14/196 (7.1%).
  
  
  CONCLUSIONS
  The overall prevalence of latex sensitivity in health-care workers in our epidemiological setting is 7.1%. An accurate diagnosis must take in account the integration of in vivo and in vitro tests with previous history of allergic disease.
authors.affiliation: Dipartimento di Medicina Clinica e delle Patologie Emergenti, Universita' di Palermo, Italy. dilo601@mbox.unipa.it
authors.forename: Gabriele
authors.initials: G
authors.lastname: Di Lorenzo
authors.forename: Francesco
authors.initials: F
authors.lastname: Vitale
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Pacor
authors.forename: Maria Esposito
authors.initials: ME
authors.lastname: Pellitteri
authors.forename: Agata
authors.initials: A
authors.lastname: Drago
authors.forename: Rosaria
authors.initials: R
authors.lastname: Cucchiara
authors.forename: Gianpiero
authors.initials: G
authors.lastname: Seroni
authors.forename: Vincenza
authors.initials: V
authors.lastname: Intonazzo
authors.forename: Nino
authors.initials: N
authors.lastname: Romano
authors.forename: Calogero
authors.initials: C
authors.lastname: Caruso
mesh_terms: D000328:Adult; D000485:Allergens / Q000009:adverse effects*; D000918:Antibody Specificity / Q000276:immunology; D003430:Cross-Sectional Studies; D005260:Female; D017575:Gloves, Protective; D006282:Health Personnel; D006769:Hospitals, General; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology / Q000276:immunology / Q000628:therapy; D007114:Immunization; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D007840:Latex / Q000009:adverse effects*; D020315:Latex Hypersensitivity / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology / Q000276:immunology / Q000628:therapy; D015995:Prevalence; D012140:Respiratory Tract Diseases / Q000453:epidemiology / Q000276:immunology; D012802:Sicily / Q000453:epidemiology; D012871:Skin Diseases / Q000453:epidemiology / Q000276:immunology; D012882:Skin Tests; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D000485:Allergens; D007840:Latex; D007073:Immunoglobulin E