title: Functionalized pyridylboronic acids and their Suzuki cross-coupling reactions to yield novel heteroarylpyridines.
abstract: 2-Bromo-5-pyridylboronic acid 2a, 2-chloro-5-pyridylboronic acid 2b, 2-methoxy-5-pyridylboronic acid 2c, and 5-chloro-2-methoxy-4-pyridylboronic acid 4 have been synthesized and shown to undergo palladium-catalyzed cross-coupling reactions with heteroaryl bromides to yield novel heteroarylpyridine derivatives. The X-ray crystal structures of 2a and 2b have been obtained.
authors.affiliation: Department of Chemistry, University of Durham, Durham, DH1 3LE England.
authors.forename: Paul R
authors.initials: PR
authors.lastname: Parry
authors.forename: Changsheng
authors.initials: C
authors.lastname: Wang
authors.forename: Andrei S
authors.initials: AS
authors.lastname: Batsanov
authors.forename: Martin R
authors.initials: MR
authors.lastname: Bryce
authors.forename: Brian
authors.initials: B
authors.lastname: Tarbit