Improved synthesis of chalcones under ultrasound irradiation.
Claisen-Schmidt condensation of acetophenone with aromatic aldehydes catalyzed by pulverized KOH and KF-Al2O3 results chalcones in 52-97% and 83-98% yields respectively in alcoholic solvent under ultrasound irradiation.
Li
Ji-Tai
JT
College of Chemistry and Environmental Science, Hebei University, Baoding 071002, People's Republic of China. orgsyn@mail.hbu.edu.cn
Yang
Wen-Zhi
WZ
Wang
Shu-Xiang
SX
Li
Sheng-Hui
SH
Li
Tong-Shuang
TS
D000447:Aldehydes / Q000737:chemistry; D000537:Aluminum Oxide / Q000737:chemistry; D002384:Catalysis; D002599:Chalcone / Q000031:analogs & derivatives* / Q000138:chemical synthesis*; D006878:Hydroxides / Q000737:chemistry; D017680:Potassium Compounds / Q000737:chemistry; D014463:Ultrasonography
D000447:Aldehydes; D006878:Hydroxides; D017680:Potassium Compounds; D002599:Chalcone; D000537:Aluminum Oxide; C029943:potassium hydroxide