Ribozymes: catalytic RNAs that cut things, make things, and do odd and useful jobs.
Catalytic RNAs, or ribozymes, are a fossil record of the ancient molecular evolution of life on earth and still provide the essential core of macromolecule synthesis in all life forms today. Are they also an avenue to the development of new catalysts to recreate evolution, or to use as therapeutics and molecule sensors.
Walter
Nils G
NG
The University of Michigan, Ann Arbor 48109, USA. nwalter@umich.edu
Engelke
David R
DR
D000818:Animals; D019143:Evolution, Molecular; D015394:Molecular Structure; D014176:Protein Biosynthesis; D012322:RNA Precursors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D016337:RNA, Catalytic / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D012335:RNA, Ribosomal / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D012322:RNA Precursors; D016337:RNA, Catalytic; D012335:RNA, Ribosomal