title: Ethical and scientific decision making in distraction osteogenesis.
abstract: OBJECTIVE
  To propose a prospective registry for distraction osteogenesis research.
  
  
  RESULTS
  The search strategy identified 82 reports, of which 11 were review articles, 17 were animal studies, 5 were theoretical models, and 49 were case reports/series.
  
  
  CONCLUSIONS
  So far, the literature concerning distraction osteogenesis does not allow reliable choices to be made on the most appropriate form of distraction osteogenesis in different clinical decisions or whether it is superior to osteotomy or nontreatment. A prospective registry is proposed to hasten critical appraisal of distraction osteogenesis.
authors.affiliation: Orthodontic Unit, Department of Oral Health and Development, University Dental Hospital of Manchester, Manchester M15 6FH, United Kingdom. bill.shaw@man.ac.uk
authors.forename: W C
authors.initials: WC
authors.lastname: Shaw
authors.forename: N A
authors.initials: NA
authors.lastname: Mandall
authors.forename: C R
authors.initials: CR
authors.lastname: Mattick
mesh_terms: D015982:Bias; D002986:Clinical Trials as Topic; D003657:Decision Making / Q000941:ethics*; D004990:Ethics, Dental; D006801:Humans; D019857:Osteogenesis, Distraction / Q000941:ethics*; D010027:Osteotomy / Q000941:ethics; D011446:Prospective Studies; D012042:Registries; D015203:Reproducibility of Results; D012107:Research Design; D012586:Science / Q000941:ethics*