Palladium-catalyzed intermolecular hydroamination of alkynes: a dramatic rate-enhancement effect of O-aminophenol.
The hydroamination of alkynes using o-aminophenol proceeds in very high to good yields in the presence of Pd(NO3)2 catalyst. Remarkable rate enhancement with o-aminophenol is presumably due to the chelation effect of the ortho OH group to palladium.
Shimada
Tomohiro
T
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
Yamamoto
Yoshinori
Y