title: Risk factors for indinavir-related renal colic in HIV patients: predictive value of indinavir dose/body mass index.
abstract: In a prospective study evaluating risk factors for indinavir-related renal colic in 555 HIV-infected patients receiving highly active antiretroviral therapy, followed-up fir 24 months, 23.6% developed one or more renal colic episodes, and 50 patients stopped indinavir. No correlation was observed between renal colic onset and sex, age, CD4 cell count, history, and hepatitis B or C virus co-infection, but baseline anthropometric values were significantly related to the onset of renal colic.
authors.affiliation: 2nd Department of Infectious Diseases Sacco Hospital, Milan, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Meraviglia
authors.forename: Elena
authors.initials: E
authors.lastname: Angeli
authors.forename: Francesca
authors.initials: F
authors.lastname: Del Sorbo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Rombolà
authors.forename: Paolo
authors.initials: P
authors.lastname: Viganò
authors.forename: Giovanna
authors.initials: G
authors.lastname: Orlando
authors.forename: Laura
authors.initials: L
authors.lastname: Cordier
authors.forename: Ivano
authors.initials: I
authors.lastname: Faggion
authors.forename: Antonietta
authors.initials: A
authors.lastname: Cargnel
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003085:Colic / Q000139:chemically induced*; D004305:Dose-Response Relationship, Drug; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D019469:Indinavir / Q000008:administration & dosage / Q000009:adverse effects*; D007669:Kidney Calculi; D007674:Kidney Diseases / Q000139:chemically induced*; D008297:Male; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors
chemical_list: D017320:HIV Protease Inhibitors; D019469:Indinavir