title: Biomimetic reduction of nimesulide with NaBH4 catalyzed by metalloporphyrins.
abstract: The biomimetic reduction of anti-inflammatory drug, nimesulide (1) with sodium borohydride catalyzed by 5,10,15,20-tetraarylporphyrinatoiron(III) chlorides [TAPFe(III)Cl] has been studied in organic solvents under anaerobic and aerobic conditions.
authors.affiliation: Department of Chemistry, University of Delhi, India. smschauhan@chemistry.du.ac.in
authors.forename: Shive Murat Singh
authors.initials: SM
authors.lastname: Chauhan
authors.forename: Srinivas Appan
authors.initials: SA
authors.lastname: Kandadai
authors.forename: Anil
authors.initials: A
authors.lastname: Kumar
mesh_terms: D032701:Biomimetics / Q000379:methods*; D001894:Borohydrides / Q000737:chemistry / Q000378:metabolism*; D002384:Catalysis / Q000187:drug effects; D008665:Metalloporphyrins / Q000737:chemistry / Q000378:metabolism*; D013449:Sulfonamides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D001894:Borohydrides; D008665:Metalloporphyrins; D013449:Sulfonamides; C025364:sodium borohydride; C012655:nimesulide