title: Haemorrhage into chronic plaque psoriasis as a consequence of disseminated intravascular coagulation.
abstract: We describe a patient with chronic plaque psoriasis who developed haemorrhage into pre-existing lesions during an episode of disseminated intravascular coagulation secondary to sepsis. Disseminated intravascular coagulation is a complex disorder characterized by widespread intravascular deposition of fibrin with consumption of coagulation factors and platelets and occurs as a consequence of many disorders that release procoagulant material into the circulation or cause widespread endothelial damage or platelet aggregation. As both disseminated intravascular coagulation and psoriasis occur relatively frequently in the general population we were surprised to find no previous reports of this phenomenon in the literature.
authors.affiliation: Departments of Dermatology and Histopathology, Middlesex Hospital, Mortimer Street, London, UK.
authors.forename: K A
authors.initials: KA
authors.lastname: Short
authors.forename: R W
authors.initials: RW
authors.lastname: Groves
authors.forename: M R
authors.initials: MR
authors.lastname: Novelli
mesh_terms: D002908:Chronic Disease; D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D006470:Hemorrhage / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000150:complications*; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology