title: [Dioxins: facts and conjectures].
abstract: Dioxins and dioxin-like substances are highly toxic and extremely dangerous chemical compounds. Dioxins are formed during the thermal process associated with the use of chlorine. 2,3,7,8-tetrachlorodibenzo-1,4-dioxin is the most toxic, the most typical and well-studied agent. The most characteristic and constant indicators of intoxication with dioxin-containing substances are altered body weight, chloracne, hepatic damage, thyroid involution, structural changes in the adrenal cortex, spleen, genitals, immunodeficiency. There is evidence for a role of these agents in the development of infertility and neonatal pathology.
authors.forename: B A
authors.initials: BA
authors.lastname: Katsnel'son
authors.forename: A A
authors.initials: AA
authors.lastname: Koseleva
authors.forename: S V
authors.initials: SV
authors.lastname: Kuz'min
authors.forename: L I
authors.initials: LI
authors.lastname: Privalova
mesh_terms: D002617:Chemical Industry; D004147:Dioxins / Q000009:adverse effects*; D004787:Environmental Pollution; D015386:Hazardous Substances / Q000009:adverse effects*; D006801:Humans; D012016:Reference Values; D012426:Russia
chemical_list: D004147:Dioxins; D015386:Hazardous Substances