Specific accumulation and growth inhibitory effects of hybrid liposomes to hepatoma cells in vitro.
Specific accumulation and growth inhibitory effects of hybrid liposomes composed of 90 mol% dimyristoylphosphatidylcholine and 10 mol% polyoxyethylene(23)dodecyl ether were obtained in human hepatoma cells without affecting normal liver cells at all.
Nakano
Koji
K
Graduate School of Applied Chemistry, Sojo University, Kumamoto, Japan.
Iwamoto
Yasunori
Y
Takata
Wataru
W
Matsumoto
Yoko
Y
Ueoka
Ryuichi
R
D000970:Antineoplastic Agents / Q000378:metabolism / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000473:pathology*; D002455:Cell Division / Q000187:drug effects; D004134:Dimyristoylphosphatidylcholine; D006801:Humans; D007700:Kinetics; D008081:Liposomes / Q000378:metabolism / Q000494:pharmacology*; D000077423:Polidocanol; D011092:Polyethylene Glycols; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D008081:Liposomes; D000077423:Polidocanol; D011092:Polyethylene Glycols; D004134:Dimyristoylphosphatidylcholine