Gene therapy--its potential in surgery.
Advances in techniques have resulted in practical applications for gene therapy, which is becoming applicable for the treatment of human disease. This review outlines the advantages and disadvantages of the techniques available. Examples of research efforts in the treatment of diseases of relevance to the surgeon (cardiovascular diseases, cancer, wound healing, fracture repair, and in organ transplantation) are presented.
Gojo
Satoshi
S
Yamamoto
Shin
S
Patience
Clive
C
LeGuern
Christian
C
Cooper
David K C
DK
D000256:Adenoviridae / Q000235:genetics; D002318:Cardiovascular Diseases / Q000628:therapy; D002986:Clinical Trials as Topic; D017102:Fracture Healing / Q000235:genetics; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000008:administration & dosage; D006801:Humans; D009369:Neoplasms / Q000628:therapy; D012190:Retroviridae / Q000235:genetics; D014180:Transplantation / Q000379:methods; D014945:Wound Healing / Q000235:genetics