Cerebral oxygen metabolism monitoring under hypothermia for severe subarachnoid hemorrhage: report of eight cases.
OBJECTIVE
The significance of cerebral oxygen metabolism monitoring under hypothermia for severe subarachnoid hemorrhage (SAH) was studied.


METHODS
Cerebral oxygen metabolism monitoring (jugular venous oxygen saturation: SjO2, arterio-jugular venous difference of oxygen: AJDO2, and oxygen extraction fraction:OEF) during hypothermia (32-34 degrees C) was evaluated in eight patients with SAH (severe vasoapasm group: five patients, and severe brain damage group: three patients).


RESULTS
In favorable cases in both groups, each parameter tended to normalize during hypothermia therapy. When changes in SjO2 were normal, however, the value of AJDO2 was low in unfavorable cases in the severe vasospasm group. In unfavorable cases in the severe brain damage group, high level of SjO2 and low level of OEF and AJDO2 were shown even if hypothermia therapy was performed.


CONCLUSIONS
The measurement of SjO2 and AJDO2 is useful for estimation of cerebral oxygen metabolism in patients with severe conscious disturbance after SAH under hypothermia therapy.
Nakamura
T
T
Department of Neurosurgery, JA-Kagawa Takinomiya General Hospital, Ayautagun, Kagawa, Japan. neuron@kms.ac.jp
Tatara
N
N
Morisaki
K
K
Kawakita
K
K
Nagao
S
S
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010101:Oxygen Consumption; D012720:Severity of Illness Index; D013345:Subarachnoid Hemorrhage / Q000378:metabolism* / Q000628:therapy*; D013687:Telencephalon / Q000378:metabolism*