Sonication induced sheet formation at the air-water interface.
A hydrophobic pentadecapeptide, AGAAAA-GAVVGGLGG (1), part of the prion sequence PrP (106-127), on fresh aqueous dissolution takes a mixture of random and sheet conformations which forms a stable monolayer with a high beta-sheet content when compressed at the air-water interface. This also develops into a kinetically stabilized beta-sheet structure on sonication.
Satheeshkumar
K S
KS
Bio Organic Laboratory, Central Leather Research Institute, Adyar, Chennai 600 020, India.
Jayakumar
R
R
D000388:Air; D000595:Amino Acid Sequence; D002942:Circular Dichroism; D006801:Humans; D008969:Molecular Sequence Data; D010165:Palladium / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D014867:Water
D010455:Peptides; D014867:Water; D010165:Palladium