Gas chromatographic determination of prostaglandins.
Progress in separation and detection of prostaglandins and the other metabolites of arachidonic acid by means of GC-ECD, GC-MS, and GC-MS-MS in the course of the past fifteen years was reviewed. One discussed the problems of sample preparation, selection of proper chromatographic conditions, and detection modes available. Finally, applications of the methods developed to detection and quantification of prostanoids in biological material was presented.
Baranowski
R
R
Department of Analytical and General Chemistry, Silesian Technical University, 9 Strzody Street, Gliwice, 44-100, Poland. baranows@polsl.gliwice.pl
Pacha
K
K
D000818:Animals; D002849:Chromatography, Gas / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D011453:Prostaglandins / Q000032:analysis* / Q000737:chemistry
D011453:Prostaglandins