title: [Chronic daily headaches caused by too much caffeine].
abstract: Caffeine dependence is a frequent cause of chronic daily headache. This condition was diagnosed in three men aged 33, 35 and 26 years, respectively, and two women aged 67 and 44 years, respectively. As little as 100 mg caffeine may be enough to cause the headache, i.e. the equivalent of one cup of coffee, one bar of dark chocolate, 2 cups of tea or 2 tablets of an analgesic-coffee combination preparation. The therapy consists of discontinuing the caffeine consumption. Assessment of caffeine use is an important part of the headache anamnesis, especially in the case of morning or weekend headaches, unexplained increase in frequency and duration of episodes, a decreased response to headache medication or chronic daily headache.
authors.affiliation: Universitair Medisch Centrum Utrecht, afd. Neurologie, Postbus 85.500, 3508 GA Utrecht. w.j.schonewille@neuro.azu.nl
authors.forename: W J
authors.initials: WJ
authors.lastname: Schonewille
mesh_terms: D000328:Adult; D000368:Aged; D002110:Caffeine / Q000009:adverse effects*; D002908:Chronic Disease; D005260:Female; D006261:Headache / Q000139:chemically induced*; D006801:Humans; D008297:Male; D019966:Substance-Related Disorders
chemical_list: D002110:Caffeine