title: Quantitative determination of the enantiomeric composition of thalidomide solutions by electrospray ionization tandem mass spectrometry.
abstract: Rapid and simple chiral analysis of thalidomide solutions is demonstrated by using electrospray ionization tandem mass spectrometry and analysis of cluster ion dissociation by the kinetic method. Average deviations of 1% between the actual and experimental enantiomeric compositions are observed.
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Daniella V
authors.initials: DV
authors.lastname: Augusti
authors.forename: Rodinei
authors.initials: R
authors.lastname: Augusti
authors.forename: Fernando
authors.initials: F
authors.lastname: Carazza
authors.forename: R Graham
authors.initials: RG
authors.lastname: Cooks
mesh_terms: D012996:Solutions; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D013237:Stereoisomerism; D013792:Thalidomide / Q000737:chemistry*
chemical_list: D012996:Solutions; D013792:Thalidomide