title: Combination AST-120 and dilazep dihydrochloride therapy reduced urinary protein excretion and serum creatinine levels in patients with chronic renal failure.
abstract: The effect of AST-120 and dilazep dihydrochloride on serum creatinine levels and urinary protein excretion was assessed in patients with chronic renal failure. We found that both drugs in combination provide an additive renoprotective effect over each drug in some chronic renal failure patients.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Nakamura
authors.forename: Kaoru
authors.initials: K
authors.lastname: Hirokawa
authors.forename: Takaharu
authors.initials: T
authors.lastname: Matsuda
authors.forename: Shiori
authors.initials: S
authors.lastname: Osada
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Noriaki
authors.initials: N
authors.lastname: Shimada
authors.forename: Hikaru
authors.initials: H
authors.lastname: Koide
mesh_terms: D000368:Aged; D002244:Carbon / Q000008:administration & dosage / Q000627:therapeutic use*; D003404:Creatinine / Q000097:blood*; D004109:Dilazep / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000008:administration & dosage / Q000627:therapeutic use*; D011507:Proteinuria / Q000097:blood* / Q000150:complications / Q000188:drug therapy*; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D010087:Oxides; D014665:Vasodilator Agents; D002244:Carbon; C040896:AST 120; D003404:Creatinine; D004109:Dilazep