title: Age-dependent phosphate homeostasis is regulated by a circulating factor.
abstract: To evaluate the age-dependent phosphate homeostasis, we studied the serum inorganic phosphate (P(i)) concentration in 78 recipients, aged 5-25 years, a year after renal transplantation (RT). The significant age-dependent decline of the serum P(i) concentration was observed in recipients (p < 0.0001) as well as in normal children. Our study revealed that a circulating factor may play a central role in the age-dependent change of phosphate regulation in human.
authors.affiliation: Department of Pediatric Nephrology, Tokyo Women's Medical University, Tokyo, Japan. naoko@pine.memail.jp
authors.forename: Naoko
authors.initials: N
authors.lastname: Matsumoto
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Komatsu
authors.forename: Motoshi
authors.initials: M
authors.lastname: Hattori
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shiraga
authors.forename: Katsumi
authors.initials: K
authors.lastname: Ito
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000375:Aging; D001798:Blood Proteins / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D006706:Homeostasis; D006801:Humans; D016030:Kidney Transplantation; D010710:Phosphates / Q000097:blood*
chemical_list: D001798:Blood Proteins; D010710:Phosphates