Phylogenetic and functional classification of ATP-binding cassette (ABC) systems.
ATP binding cassette (ABC) systems constitute one of the most abundant superfamilies of proteins. They are involved in the transport of a wide variety of substances, but also in many cellular processes and in their regulation. In this paper, we made a comparative analysis of the properties of ABC systems and we provide a phylogenetic and functional classification. This analysis will be helpful to accurately annotate ABC systems discovered during the sequencing of the genome of living organisms and to identify the partners of the ABC ATPases.
Bouige
Philippe
P
Unité de Programmation Moléculaire et Toxicologie génétique, CNRS URA 1444, Institut Pasteur, 25, Rue du Dr. Roux, 7572, Paris, Cedex 15, France. elidassa@pasteur.fr
Laurent
David
D
Piloyan
Linda
L
Dassa
Elie
E
D018528:ATP-Binding Cassette Transporters / Q000737:chemistry / Q000145:classification* / Q000235:genetics* / Q000378:metabolism; D001419:Bacteria / Q000235:genetics / Q000378:metabolism; D001693:Biological Transport, Active; D006801:Humans; D015394:Molecular Structure; D010802:Phylogeny
D018528:ATP-Binding Cassette Transporters