title: [Scanning electron microscopic characterization of resorption lacunae and perforations in the cancellous bone of the human femoral head].
abstract: STAND: Light microscopic investigation of histologic and grinding sections indicates structural differences by resorption lacunae and perforations
  
  
  OBJECTIVE
  Is it possible to characterize different types of resorption lacunae and perforations on the basis of ultrastructural differences within them? AIM. Morphological characterization of resorption lacunae and perforations in cancellous bone of the human femoral head
  
  
  METHODS
  Samples from the femoral head of 28 patients without skeletal diseases were macerated, dried, gold sputtered and analysed by scanning electron microscopy. RESULTS. We were able to distinguish two types of resorptions lacunae as well as two types of perforation: The longitudinal extended resorption (LER), the reticulate patched resorption (RPR), the lacunar perforation (LP), the tunneling perforation (TP). Moreover we demarcate perforations from blood vessel canals.
  
  
  CONCLUSIONS
  The differentiated types of resorption lacunae and perforations suggest the influence of local factors which regulates osteoclastic activity or indicate different subspecies of osteoclasts.
authors.affiliation: Abteilung für Knochenpathologie/Zentrum für Biomechanik, Universität Hamburg, Deutschland, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Gentsch
authors.forename: E
authors.initials: E
authors.lastname: Kaiser
authors.forename: G
authors.initials: G
authors.lastname: Delling
mesh_terms: D001847:Bone Diseases / Q000473:pathology; D001862:Bone Resorption / Q000473:pathology*; D003937:Diagnosis, Differential; D005269:Femur / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010010:Osteoclasts / Q000648:ultrastructure