title: A concise, asymmetric synthesis of tetramic acid derivatives.
abstract: [reaction: see text] A simple, asymmetric synthesis of tetramic acid derivatives is described in this paper. The key step is a carbonyl transfer from carbonyldiimidazole (CDI) to alpha-diimines (I) to form N-alkyl-4-alkylamino-5-methylenepyrrol-2-ones (II). In turn, these compounds can be easily transformed into tetramic acid derivatives (III) in two additional steps.
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia, E-46100 Burjassot, Spain. santos.fustero@uv.es
authors.forename: Santos
authors.initials: S
authors.lastname: Fustero
authors.forename: Marta
authors.initials: M
authors.lastname: García de la Torre
authors.forename: Juan F
authors.initials: JF
authors.lastname: Sanz-Cervera
authors.forename: Carmen
authors.initials: C
authors.lastname: Ramírez de Arellano
authors.forename: Julio
authors.initials: J
authors.lastname: Piera
authors.forename: Antonio
authors.initials: A
authors.lastname: Simón