title: Congenital oligodendroglioma with initial manifestation of jaundice.
abstract: Neonatal brain tumor is a rare clinical entity. The initial presentation in affected newborn infants is often subtle, nonspecific, and rarely includes focal neurologic signs. We report a 2-day-old male infant with congenital oligodendroglioma with initial manifestations of hyperbilirubinemia. Phototherapy was started immediately after admission. Because of a tense anterior fontanel and irritable crying, head ultrasonography, computed tomography, and magnetic resonance imaging were performed and revealed a heterogenous brain tumor in the left temporoparietal lobe. Craniotomy and tumor evacuation was performed, and WHO grade III anaplastic oligodendroglioma was confirmed by the pathologic studies. The patient was discharged 3 weeks later, and outpatient follow-up examination revealed a normally developed infant at 6 months of age. The cause of jaundice was thought to be secondary to tumor hemorrhage, which was not infrequent in neonatal brain tumor.
authors.affiliation: Department of Pediatrics, National Taiwan University Hospital, National Taiwan University, College of Medicine, Taipei, Taiwan, Republic of China.
authors.forename: Wu-Shiun
authors.initials: WS
authors.lastname: Hsieh
authors.forename: Rey In
authors.initials: RI
authors.lastname: Lien
authors.forename: Tai Ngar
authors.initials: TN
authors.lastname: Lui
authors.forename: Chao Ran
authors.initials: CR
authors.lastname: Wang
authors.forename: Shih Ming
authors.initials: SM
authors.lastname: Jung
mesh_terms: D001932:Brain Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D003399:Craniotomy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000175:diagnosis / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009837:Oligodendroglioma / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D010296:Parietal Lobe / Q000473:pathology / Q000601:surgery; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed