A clone of coagulase-negative staphylococci among patients with post-cardiac surgery infections.
Coagulase-negative staphylococci (CoNS) are important causes of hospital-acquired infections such as infections after cardiac surgery. Efforts to reduce these infections are hampered by the lack of knowledge concerning the epidemiology of CoNS in this setting. Forty strains of CoNS collected during the surgical revision of 27 patients operated on between 1997 and 2000 were analysed. Strains were also collected from the ambient air in the operating suite. Their pulsed-field gel electrophoresis (PFGE) characteristics and antibiotic resistance were analysed. Using PFGE 19 of 40 strains from 15 of 27 patients were shown to belong to one clone, and strains from this clone were also isolated from the ambient air. This clone had caused infections throughout the period. Antibiotic resistance did not correlate with PFGE patterns. Using PFGE one clone could be identified that caused 56% of the CoNS infections during this period. A strain from this clone was also found in the air of the operating suite suggesting the origin of the CoNS causing infections was the hospital environment.
Tegnell
A
A
Division of Infectious Diseases, Department of Health and Environment, Linköping University, Sweden. Anders.Tegnell@inf.liu.se
Saeedi
B
B
Isaksson
B
B
Granfeldt
H
H
Ohman
L
L
D000368:Aged; D002999:Clone Cells; D003030:Coagulase / Q000145:classification / Q000302:isolation & purification*; D001026:Coronary Artery Bypass; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000453:epidemiology*
D003030:Coagulase