Goat immune response to capripox vaccine expressing the hemagglutinin protein of peste des petits ruminants.
Sheep-pox and capripox are contagious diseases of domestic small ruminants for which the causal agent is a poxvirus classified into the Capripoxvirus genus. Viruses of this group have a host range specific to sheep, goats, cattle, and possibly buffalo. Thus, they are clearly indicated as vectors for the development of recombinant vaccines for peste des petits ruminants (PPR). Here we report the immune response of goats inoculated with a recombinant capripox-PPR hemagglutinin.
Diallo
A
A
Cirad, Programme Santé Animale, Campus International de Baillarguet, 34398 Montpellier Cedex 05, France.
Minet
C
C
Berhe
G
G
Le Goff
C
C
Black
D N
DN
Fleming
M
M
Barrett
T
T
Grillet
C
C
Libeau
G
G
D000818:Animals; D018151:Capripoxvirus / Q000235:genetics / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D005822:Genetic Vectors; D015511:Goat Diseases / Q000517:prevention & control* / Q000821:virology; D006041:Goats; D006389:Hemagglutinins, Viral / Q000235:genetics / Q000276:immunology*; D007958:Leukocyte Count / Q000662:veterinary; D007962:Leukocytes / Q000276:immunology; D029021:Peste-des-Petits-Ruminants / Q000517:prevention & control / Q000662:veterinary*; D018107:Peste-des-petits-ruminants virus / Q000235:genetics / Q000276:immunology*; D011213:Poxviridae Infections / Q000517:prevention & control / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000517:prevention & control; D013045:Species Specificity; D014614:Vaccines, Synthetic; D014765:Viral Vaccines
D006389:Hemagglutinins, Viral; D014614:Vaccines, Synthetic; D014765:Viral Vaccines