Brine shrimp lethality bioassay of selected Indian medicinal plants.
Ethanolic extracts of six Indian medicinal plants, piperine, guggulsterone E and guggulsterone Z were tested for cytotoxicity using brine shrimp lethality test. Piper longum showed most potent cytotoxic activity. Piperine, guggulsterone E and guggulsterone Z showed potent activity with LC(50) 2.4, 8.9 and 4.9, respectively.
Padmaja
R
R
Bioassay Unit, Research & Development Centre, Natural Remedies Pvt Ltd, Plot No 5B, Veerasandra Indl Area, Hosur Road, Bangalore 561 229, India.
Arun
P C
PC
Prashanth
D
D
Deepak
M
M
Amit
A
A
Anjana
M
M
D000818:Animals; D001156:Artemia / Q000187:drug effects*; D007194:India; D007928:Lethal Dose 50; D008519:Medicine, Traditional; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000145:classification*
D010936:Plant Extracts