Positron emission tomography, echo-doppler, and exercise studies of functional capacity in hypertensive heart disease.
BACKGROUND
This study examines the relationship between functional capacity, left ventricular diastolic function, and myocardial perfusion reserve (MPR) in patients with left ventricular hypertrophy (LVH).


METHODS
We studied 16 patients with LVH and 10 controls. Functional capacity was assessed by cardiopulmonary exercise, MPR by positron emission tomography, and left ventricular diastolic function by echo-Doppler.


RESULTS
Functional capacity and MPR were significantly lower in the patients. Functional capacity correlated positively with MPR and left ventricular diastolic function.


CONCLUSIONS
Diminished functional capacity in patients with hypertension-induced LVH is related to the impairment in MPR and left ventricular diastolic function.
Akinboboye
Olakunle O
OO
Non-Invasive Laboratory, St. Francis Hospital, Roslyn, State University of New York at Stony Brook, USA. ooa2@columbia.edu
Idris
Olajide
O
Goldsmith
Rochelle
R
Berekashvili
Kati
K
Chou
Ru-Ling
RL
Bergman
Steven R
SR
D000328:Adult; D015331:Cohort Studies; D003971:Diastole; D015150:Echocardiography, Doppler; D005080:Exercise Test; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D014055:Tomography, Emission-Computed; D014655:Vascular Resistance