title: [A method for potentiation of local anesthesia for tooth removal and pulp extirpation].
abstract: Local anesthesia can be considered adequate in 22% cases, which is explained by the absence of inhibitory effect on allogens, persistence of psychoemotional tension, and effector reactions. Therefore it is recommended to potentiate local anesthesia by a drug complex including analgesic ketrodole, tranquilizer diazepam, and alpha-adrenoagonist clofelin, used transbuccally 8-10 min before anesthesia. This pretreatment 3-fold increased the adequacy of local anesthesia for tooth removal and pulp extirpation.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Mishunin
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D003000:Clonidine / Q000627:therapeutic use; D016854:Dental Anxiety / Q000188:drug therapy / Q000523:psychology; D003787:Dental Pulp Devitalization / Q000523:psychology; D003975:Diazepam / Q000627:therapeutic use; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006801:Humans; D011229:Preanesthetic Medication / Q000379:methods*; D014081:Tooth Extraction / Q000523:psychology
chemical_list: D000316:Adrenergic alpha-Agonists; D018712:Analgesics, Non-Narcotic; D014151:Anti-Anxiety Agents; D003000:Clonidine; D003975:Diazepam