Have we solved the problem of late thrombosis?
Late thrombosis (angiographic total occlusion associated with an acute coronary syndrome) is potentially a life-threatening complication after intracoronary radiation therapy. This review is intended to explore the pre-clinical and clinical evidence for late thrombosis, discuss the etiology, and provide guidelines for future management. Although we have gained a greater understanding of this complex entity, further research is required to curtail late thrombosis rates.
Ajani
A E
AE
Cardiovascular Research Institute, Washington Hospital Center, Washington DC, USA.
Cheneau
E
E
Leborgne
L
L
Wolfram
R
R
Waksman
R
R
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D000818:Animals; D001918:Brachytherapy; D002986:Clinical Trials as Topic; D015331:Cohort Studies; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000628:therapy*; D023903:Coronary Restenosis / Q000517:prevention & control*; D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage; D015607:Stents; D013552:Swine; D013927:Thrombosis / Q000517:prevention & control*; D013997:Time Factors