title: Plasma exchange for thrombotic thrombocytopenic purpura: report of 2 cases.
abstract: Two patients with thrombotic thrombocytopenic purpura (TTP) were treated with daily plasma exchange with fresh frozen plasma of the plasma volume of the body (40 mg/kg . b.w.), in combination with red blood cell transfusion. The clinical symptoms resolved immediately and the parameters of laboratory examination improved promptly after the treatment, and follow-up of the 2 patients revealed no recurrent TTP episodes. This result indicates that plasma exchange is obviously superior to traditional treatment modalities and has significantly changed the course of TTP.
authors.affiliation: Department of Hematology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Yin
authors.forename: Fan-Yi
authors.initials: FY
authors.lastname: Meng
authors.forename: Shu-Yun
authors.initials: SY
authors.lastname: Zhou
authors.forename: Jing-Na
authors.initials: JN
authors.lastname: Niu
authors.forename: Jun-Ti
authors.initials: JT
authors.lastname: Li
authors.forename: Fu
authors.initials: F
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010951:Plasma Exchange; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy*; D012008:Recurrence; D016896:Treatment Outcome