title: [The characteristics of PCNA expression in hypertrophic scars and chronic ulcers and implication of the expression].
abstract: OBJECTIVE
  To investigate the characteristics of PCNA expression in hypertrophic scars and chronic ulcers and to discuss its relation to their formation.
  
  
  METHODS
  The expressive quantity and sites of PCNA were detected with the immunohistochemical SP method.
  
  
  RESULTS
  PCNA was expressed in all samples. The expressive quantity in hypertrophic scars was higher than chronic ulcers(P < 0.01). The expressive sites of all samples were in the nucleus of fibroblasts and capillary endothelial cells.
  
  
  CONCLUSIONS
  The expressive quantity of PCNA was more in hypertrophic scars and less n chronic ulcers. The quantitative difference of expression between hypertrophic scars and chronic ulcers may be correlated to their formation.
authors.affiliation: 304th Hospital of PLA, Beijing 100037, China.
authors.forename: Tongzhu
authors.initials: T
authors.lastname: Sun
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Fu
authors.forename: Xiaoman
authors.initials: X
authors.lastname: Gu
authors.forename: Yinhui
authors.initials: Y
authors.lastname: Yang
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Sun
mesh_terms: D000328:Adult; D017439:Cicatrix, Hypertrophic / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D018809:Proliferating Cell Nuclear Antigen / Q000096:biosynthesis*; D012883:Skin Ulcer / Q000378:metabolism* / Q000473:pathology
chemical_list: D018809:Proliferating Cell Nuclear Antigen