Association of HLA-DPB1 gene with endometriosis in women of Guangdong Province in China.
OBJECTIVE
To analyze the hereditary susceptibility in patients with endometriosis by way of genotyping of HLA-DPB1 alleles.


METHODS
The allelic types of HLA-DPB1 were detected by sequence-based typing (SBT) in 38 patients with endometriosis and 36 healthy women as the control.


RESULTS
Significant differences in the frequency of HLA-DRB1 allele was not observed between endometriotic patients and normal subjects.


CONCLUSIONS
HLA-DPB1 allele may not be related to endometriosis.
He
Yuan-Li
YL
Department of Gynecology and Obstetrics, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China.
Zong
Li-Li
LL
Peng
Dong-Xian
DX
Liu
Ze-Huan
ZH
Lin
Jiang-Hai
JH
Xu
An-Long
AL
D000328:Adult; D000483:Alleles; D002681:China; D004715:Endometriosis / Q000235:genetics* / Q000473:pathology; D005260:Female; D005787:Gene Frequency; D006682:HLA-DP Antigens / Q000235:genetics*; D059868:HLA-DP beta-Chains; D006801:Humans; D008875:Middle Aged
D006682:HLA-DP Antigens; D059868:HLA-DP beta-Chains; C071170:HLA-DPB1 antigen