Time-delayed spread of viruses in growing plaques.
The spread of viruses in growing plaques predicted by classical models is greater than that measured experimentally. There is a widespread belief that this discrepancy is due to biological factors. Here we show that the observed speeds can be satisfactorily predicted by a purely physical model that takes into account the delay time due to virus reproduction inside infected cells. No free or adjustable parameters are used.
Fort
Joaquim
J
Departament de Física, Universitat de Girona, Campus de Montilivi, 17071 Girona, Catalonia, Spain.
Méndez
Vicenç
V
D017123:Bacteriophage T7 / Q000254:growth & development*; D004926:Escherichia coli / Q000821:virology*; D008954:Models, Biological; D010948:Viral Plaque Assay