title: [Detection of phospholipidolytic Candida albicans isolated from saliva of children with Down's syndrome].
abstract: The childhood is one of the most propitious period of the life to the occurrence of infection by yeasts of the genus Candida. In children with Down's syndrome, besides the predispose factors to bucal candidiasis; macroglossia, bucal muscular incompetence, frequent respiratory diseases, motor difficulty and immunologic deficit are mentioned as additional elements for this fungus disease. It was verified that the children attacked by this syndrome have much more strains of Candida than other children. The aim of this study was to detect the prevalence of phospholipase producer, Candida on the saliva of children with Down's syndrome. Candida albicans was the only identified specie of Candida. The phospholipase production was found in isolated strains from both of study and control. However, the isolated strains of the group of children with Down's syndrome have strongly present phospholipidolitic.
authors.affiliation: Departamento em Medicina Tropical e Microbiologia/Imunologia, Universidade Federal de Goiás, Brasil.
authors.forename: Evandro L
authors.initials: EL
authors.lastname: Ribeiro
authors.forename: C De Castro
authors.initials: Cde C
authors.lastname: Campos
authors.forename: A M Costa
authors.initials: AM
authors.lastname: Crespo
authors.forename: Jovirês S
authors.initials: JS
authors.lastname: Castro
authors.forename: Frederico P
authors.initials: FP
authors.lastname: Rocha
authors.forename: Marcella
authors.initials: M
authors.lastname: Alves
authors.forename: Mariella S
authors.initials: MS
authors.lastname: Goulart
authors.forename: Cléver
authors.initials: C
authors.lastname: Cardoso
authors.forename: Wesley
authors.initials: W
authors.lastname: Ferreira
authors.forename: Plínio Lázaro
authors.initials: PL
authors.lastname: Naves
authors.forename: A José
authors.initials: AJ
authors.lastname: Soares
authors.forename: Simone R
authors.initials: SR
authors.lastname: Miranda
authors.forename: Fabiana C
authors.initials: FC
authors.lastname: Pimenta
mesh_terms: D002176:Candida albicans / Q000201:enzymology* / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000382:microbiology*; D006801:Humans; D007223:Infant; D010740:Phospholipases / Q000378:metabolism*; D012463:Saliva / Q000382:microbiology*
chemical_list: D010740:Phospholipases