title: Cortical potential imaging of episodic memory encoding.
abstract: Previous findings suggest that episodic memory encoding is subserved by different brain structures that interplay and transform experience into memories. The present study aims to identify topographic location of the underlying neural generators, and correlate their activities with the subsequent memory effect using electrophysiological neuroimaging of the event-related potentials (ERPs) recorded from 11 healthy subjects participating in word encoding tasks. Cortical potentials were imaged noninvasively from scalp ERPs. Different levels of brain activation were found in the left inferior prefrontal, left temporal and left parietal lobes with different latencies after onset of event. It is concluded that these regions work jointly across both spatial and temporal domains to promote verbal memory formation.
authors.affiliation: Department of Bioengineering, University of Illinois at Chicago, USA.
authors.forename: Jie
authors.initials: J
authors.lastname: Lian
authors.forename: Abraham
authors.initials: A
authors.lastname: Goldstein
authors.forename: Emanuel
authors.initials: E
authors.lastname: Donchin
authors.forename: Bin
authors.initials: B
authors.lastname: He
mesh_terms: D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology; D017397:Prefrontal Cortex / Q000502:physiology; D013702:Temporal Lobe / Q000502:physiology