title: Aquatic effects assessment: needs and tools.
abstract: In the assessment of the adverse effects pollutants can produce on exposed ecosystems, different approaches can be followed depending on the quality and quantity of information available, whose advantages and limits are discussed with reference to the aquatic compartment. When experimental data are lacking, a predictive approach can be pursued by making use of validated quantitative structure-activity relationships (QSARs), which provide reliable ecotoxicity estimates only if appropriate models are applied. The experimental approach is central to any environmental hazard assessment procedure, although many uncertainties underlying the extrapolation from a limited set of single species laboratory data to the complexity of the ecosystem (e.g., the limitations of common summary statistics, the variability of species sensitivity, the need to consider alterations at higher level of integration) make the task difficult. When adequate toxicity information are available, the statistical extrapolation approach can be used to predict environmental compatible concentrations.
authors.affiliation: Laboratorio di Tossicologia Comparata ed Ecotossicologia, Istituto Superiore di Sanità, V.le Regina Elena, 299, 00161 Roma. marchini@iss.it
authors.forename: Silvia
authors.initials: S
authors.lastname: Marchini
mesh_terms: D000818:Animals; D017753:Ecosystem; D007928:Lethal Dose 50; D009930:Organic Chemicals / Q000032:analysis / Q000633:toxicity; D021281:Quantitative Structure-Activity Relationship; D012107:Research Design; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*; D014876:Water Pollution / Q000009:adverse effects*
chemical_list: D009930:Organic Chemicals; D014874:Water Pollutants, Chemical