[Modest clinical benefits of ASAT analysis in today's health care. A case report of macro-ASAT giving rise to pathologically increased ASAT levels].
Aspartate aminotransferase (AST) may occur as a macroenzyme after forming a complex with immunoglobulins. The complex results in decreased plasma clearance and thus elevated AST levels. So far, macro-AST has only been described in a few patients. Here, we report a case of macro-AST in a healthy female. Clinicians should be aware of this phenomenon so that patients are not subjected to unnecessary investigations.
Larsson
Anders
A
Avdelningen för klinisk kemi och farmakologi, Akademiska sjukhuset, Uppsala. anders.larsson@clm.uas.lul.se
Karlsson
Bengt
B
D000328:Adult; D001219:Aspartate Aminotransferases / Q000097:blood*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D046911:Macromolecular Substances; D012016:Reference Values
D007136:Immunoglobulins; D046911:Macromolecular Substances; D001219:Aspartate Aminotransferases