title: Rapid and complete resolution of proteinuria due to renal amyloidosis in a patient with rheumatoid arthritis treated with infliximab.
abstract: We describe herein a patient with rheumatoid arthritis who developed proteinuria due to AA amyloidosis, in whom the inflammatory disease was rapidly and completely suppressed by treatment with infliximab. This response was accompanied by resolution of the proteinuria and stabilization of the amyloid deposits as seen on serial (123)I-labeled serum amyloid P scintigraphy.
authors.affiliation: Department of Rheumatology, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel. oribe14@netvision.net.il
authors.forename: Ori
authors.initials: O
authors.lastname: Elkayam
authors.forename: Philip N
authors.initials: PN
authors.lastname: Hawkins
authors.forename: Helen
authors.initials: H
authors.lastname: Lachmann
authors.forename: Michael
authors.initials: M
authors.lastname: Yaron
authors.forename: Dan
authors.initials: D
authors.lastname: Caspi
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D018501:Antirheumatic Agents / Q000008:administration & dosage*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000069285:Infliximab; D007668:Kidney / Q000502:physiology; D011507:Proteinuria / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D000069285:Infliximab