title: Management of intracranial infectious aneurysms: a series of 16 cases.
abstract: OBJECTIVE
  The purpose of this study was to better define the management of intracranial infectious aneurysms.
  
  
  METHODS
  We present a retrospective review of the management of 16 patients with intracranial infectious aneurysms. The mean follow-up period was 86 months.
  
  
  RESULTS
  None of the patients had a rehemorrhage during antibiotic treatment. The mortality and long-term outcome from ruptured intracranial infectious aneurysms may be better than previously thought. There was no significant difference in long-term outcome between patients with single or multiple infectious aneurysms or between patients who underwent surgical resection and those who were treated only with antibiotics.
  
  
  CONCLUSIONS
  Operative treatment should be pursued for patients with ruptured infectious aneurysms. Patients with unruptured intracranial infectious aneurysms should be observed during antibiotic therapy and followed up with cerebral angiography. Surgical resection should be considered if the aneurysm enlarges and the patient's general medical condition allows general anesthesia to be tolerated.
authors.affiliation: Department of Neurosurgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
authors.forename: Loi K
authors.initials: LK
authors.lastname: Phuong
authors.forename: Michael
authors.initials: M
authors.lastname: Link
authors.forename: Eelco
authors.initials: E
authors.lastname: Wijdicks
mesh_terms: D000785:Aneurysm, Infected / Q000000981:diagnostic imaging / Q000382:microbiology / Q000401:mortality / Q000628:therapy*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002533:Cerebral Angiography; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000382:microbiology / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents