title: Ethical issues in transplantation: living related donation in the setting of severe neurological damage without brain death.
abstract: The waiting list for renal transplantation has grown at an alarming rate over the last 2 decades, resulting in increased waiting times and deaths on the waiting list. To increase the number of available organs for transplantation, aggressive public education programs have been developed. The federal government has strengthened hospital regulations ensuring referral of all potential donors to organ recovery agencies, and living donor programs no longer limit donation to genetically related donors and recipients. We present a case that illustrates the complex ethical issues that are integral to the field of transplantation and the allocation of a scarce resource: a 50-year-old man who has a daughter with end-stage renal disease has suffered a severe cerebral vascular accident but is neither brain-dead nor a candidate for "non-heart-beating" donation. Given his poor prognosis, should the father be able to donate his kidney to the daughter in his compromised condition?
authors.affiliation: Department of Medicine, University of Mississippi Medical Center, Jackson 39216, USA. sschlessinger@medicine.umsmed.edu
authors.forename: Shirley
authors.initials: S
authors.lastname: Schlessinger
authors.forename: Errol D
authors.initials: ED
authors.lastname: Crook
authors.forename: Ruth
authors.initials: R
authors.lastname: Black
authors.forename: Henry
authors.initials: H
authors.lastname: Barber
mesh_terms: D000328:Adult; D003128:Coma; D004992:Ethics, Medical; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D016030:Kidney Transplantation / Q000941:ethics*; D019520:Living Donors; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012306:Risk; D020521:Stroke / Q000473:pathology; D009927:Tissue and Organ Procurement