title: Different distribution of Dukes' stage between proximal and distal colorectal cancer.
abstract: OBJECTIVE
  As different features of colorectal cancer between proximal and distal sites are influenced mainly by proximal shift and diagnostic improvement, a comparison of proximal and distal cancer sites may provide clues as to appropriate strategy for colorectal cancer treatment.
  
  
  METHODS
  The clinicopathological data on 676 patients with colorectal cancer was compared regarding the proximal and distal sites.
  
  
  RESULTS
  In cases of cancer without metastasis (Dukes' A or B), the incidence of Dukes' A was higher in the distal than in the proximal site (11.2% vs. 24.3%), while the incidence of Dukes' B was lower in the distal than the proximal site. In cases of cancer with metastasis (Dukes' C or D), the incidence of Dukes' C and Dukes' D tumors was similar between proximal and distal sites.
  
  
  CONCLUSIONS
  A large number of Dukes' A cancer in distal site may be slow growing with low metastatic potential.
authors.affiliation: Department of Surgery II, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Ikeda
authors.forename: Kazunari
authors.initials: K
authors.lastname: Akagi
authors.forename: Junko
authors.initials: J
authors.lastname: Kinoshita
authors.forename: Toru
authors.initials: T
authors.lastname: Abe
authors.forename: Mituhiro
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Masaki
authors.initials: M
authors.lastname: Mori
authors.forename: Keizo
authors.initials: K
authors.lastname: Sugimachi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016019:Survival Analysis