title: [A case of fibrosing mediastinitis manifesting recurrent nerve palsy].
abstract: A 68 year-old man was referred and admitted to our hospital because of hoarseness due to recurrent nerve palsy and an anterior mediastinal tumor detected on chest CT. Chest CT showed a low-density tumor surrounding the aorta and branching arteries. Chest MRI revealed a low-intensity tumor in both T1- and T2-weighted images. The tumor was adjacent to the heart and aorta in the upper anterior mediastinum. A biopsy was performed under minimally invasive video-assisted thoracic surgery (VATS) and a diagnosis of fibrosing mediastinitis was made histopathologically. Oral prednisolone treatment markedly reduced the tumor and improved not only abnormal laboratory data such as C-reactive protein, but also the hoarseness. We report herein that steroid monotherapy was successful in treating a case of fibrosing mediastinitis manifesting recurrent nerve palsy.
authors.affiliation: Department of Respiratory Medicine, Osaka Police Hospital, Osaka.
authors.forename: Seigo
authors.initials: S
authors.lastname: Minami
authors.forename: Mitsuko
authors.initials: M
authors.lastname: Asai
authors.forename: Kouta
authors.initials: K
authors.lastname: Iwahori
authors.forename: Tomoki
authors.initials: T
authors.lastname: Utsumi
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Kido
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Komuta
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D005355:Fibrosis; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000008:administration & dosage; D014826:Vocal Cord Paralysis / Q000209:etiology*
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone