title: Focus diagnosis of epilepsy using near-infrared spectroscopy.
abstract: OBJECTIVE
  We sought to establish a noninvasive method for focus diagnosis of epilepsy.
  
  
  METHODS
  We examined the use of multichannel near-infrared spectroscopy (NIRS). It is known as a noninvasive method of functional brain mapping. We monitored cerebral blood volume change with NIRS during long-term EEG monitoring of epilepsy in 32 cases with intractable epilepsies to diagnose the epileptogenic focus.
  
  
  RESULTS
  In 96% of cases, NIRS showed significant hyperperfusion in the side of seizure foci, whereas ictal SPECT showed hyperperfusion in 69% of cases.
  
  
  CONCLUSIONS
  Ictal NIRS is a reliable method to evaluate the focus side in epilepsy, especially when it is coupled with ictal SPECT.
authors.affiliation: Department of Neurosurgery, Tokyo Metropolitan Police Hospital, Tokyo, Japan. eiju-ind@umin.ac.jp
authors.forename: Eiju
authors.initials: E
authors.lastname: Watanabe
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Nagahori
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Mayanagi
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000000981:diagnostic imaging; D017034:Epilepsy, Frontal Lobe / Q000175:diagnosis / Q000000981:diagnostic imaging; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010296:Parietal Lobe; D018579:Patient Selection; D012640:Seizures / Q000175:diagnosis* / Q000000981:diagnostic imaging; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation; D015899:Tomography, Emission-Computed, Single-Photon