Wound healing activity and systemic effects of Vernonia scorpioides extract in guinea pig.
The ethanolic leaves extract of Vernonia scorpioides was investigated for its wound healing activity in guinea pigs. Administered once a day for 30 days, 200 mg of a hydrogel containing 50% of extract did not accelerate the closure time, but improved regeneration and organization of the new tissue.
Leite
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Núcleo de Investigações Químico-Farmacêuticas, Curso de Farmácia, CCS, Universidade do Vale do Itajaí (UNIVALI). Rua: Uruguai, 458 Itajaí, Santa Caterina, 88302-202, Brazil. snleite@ccs.univali.br
Palhano
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Almeida
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Biavatti
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MW
D000279:Administration, Cutaneous; D000818:Animals; D001773:Blood Cells / Q000187:drug effects*; D004334:Drug Administration Schedule; D005260:Female; D006168:Guinea Pigs; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D035741:Vernonia; D014945:Wound Healing / Q000187:drug effects*
D010936:Plant Extracts; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate