title: The implications of re-analysing radiation-induced leukaemia in atomic bomb survivors: risks for acute and chronic exposures are different.
abstract: Implications of risk estimates, as required for practical radiation protection purposes, were explored through a preliminary re-analysis of leukaemia in the Japanese atomic bomb survivors using a biologically based cancer model. The calculations for the risks posed for contracting leukaemia pointed to important differences between low-dose-rate ('chronic') and high-dose-rate ('acute') exposures. For example, the risks caused by long-term ('chronic') exposures are calculated to be substantially lower than those for 'acute' exposures. In view of these model predictions the results of epidemiological studies are discussed.
authors.affiliation: RIVM, Bilthoven, The Netherlands.
authors.forename: H P
authors.initials: HP
authors.lastname: Leenhouts
authors.forename: M J P
authors.initials: MJ
authors.lastname: Brugmans
authors.forename: H
authors.initials: H
authors.lastname: Bijwaard
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007564:Japan; D007953:Leukemia, Radiation-Induced / Q000209:etiology*; D008297:Male; D008962:Models, Theoretical; D009689:Nuclear Warfare; D011829:Radiation Dosage; D012306:Risk