Neuroleptic malignant syndrome with prolonged catatonia in a dopa-responsive dystonia patient.
The authors describe a patient with dopa-responsive dystonia who developed neuroleptic malignant syndrome with prolonged catatonia following treatment with neuroleptic agents. Use of these agents probably expanded the patient's neuronal dysfunction beyond the nigrostriatal system to involve multiple dopaminergic systems. Electroconvulsive treatment alleviated the prolonged catatonia.
Ihara
M
M
Department of Neurology, Kyoto University Graduate School of Medicine, Japan. ihara@kuhp.kyoto-u.ac.jp
Kohara
N
N
Urano
F
F
Ichinose
H
H
Takao
S
S
Nishida
T
T
Saiki
H
H
Kawamoto
Y
Y
Ikeda
A
A
Takagi
S
S
Shibasaki
H
H
D000328:Adult; D002389:Catatonia / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D004421:Dystonia / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics; D004569:Electroencephalography / Q000187:drug effects / Q000706:statistics & numerical data; D005260:Female; D006136:GTP Cyclohydrolase / Q000235:genetics; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy
D007980:Levodopa; D006136:GTP Cyclohydrolase