title: Extramedullary plasmacytoma of the cavernous sinus.
abstract: We present the case of an 80-year-old male with an history of multiple myeloma (MM) stage I with extramedullary plasmacytoma of the neck, diagnosed 18 months before and in complete remission after radiation therapy and melphalan-prednisone therapy. He was admitted with signs and symptoms characteristic for cavernous sinus syndrome, including diplopia, exophthalmia, ptosis and orbital pain. Magnetic resonance imaging showed a mass lesion in the cavernous sinus, consistent with relapsing extramedullary plasmacytoma. The patient received palliative radiation therapy and high dose dexamethasone, but treatment failed and the patient died. This case represents one of the few reports of extramedullary plasmacytoma of the cavernous sinus. The development of a clinical presentation of cavernous sinus syndrome in a patient with a history of MM or extramedullary plasmacytoma should raise the suspicion of a plasmacytic involvement of the cavernous sinus.
authors.affiliation: Department of Medical Oncology and Hematology, Academic Hospital, Free University Brussels (VUB), Belgium. isabelle.vandebroek@az.vub.ac.be
authors.forename: I
authors.initials: I
authors.lastname: Vande Broek
authors.forename: T
authors.initials: T
authors.lastname: Stadnik
authors.forename: A
authors.initials: A
authors.lastname: Meurs
authors.forename: J
authors.initials: J
authors.lastname: Maes
authors.forename: B
authors.initials: B
authors.lastname: Van Camp
authors.forename: R
authors.initials: R
authors.lastname: Schots
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002426:Cavernous Sinus; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010954:Plasmacytoma / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed