title: Ru3(CO)12-catalyzed C-H/CO/olefin coupling of N-pyridylindolines. Direct carbonylation at a C-H bond delta to the pyridine nitrogen.
abstract: The reaction of N-pyridylindolines with CO and ethylene in the presence of Ru3(CO)12 results in direct carbonylation at a C-H bond delta to the pyridine sp2 nitrogen, which represents a new type of C-H/CO/olefin coupling. The presence of a pyridine ring as a directing group on the substrates is essential for the reaction to proceed. The choice of N,N-dimethylacetamide (DMA) as the solvent is crucial for the reaction to proceed efficiently.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan. chatani@chem.eng.osaka-u.ac.jp
authors.forename: Naoto
authors.initials: N
authors.lastname: Chatani
authors.forename: Shuhei
authors.initials: S
authors.lastname: Yorimitsu
authors.forename: Taku
authors.initials: T
authors.lastname: Asaumi
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Kakiuchi
authors.forename: Shinji
authors.initials: S
authors.lastname: Murai