Egb 761 in the postgenomic era: new tools from molecular biology for the study of complex products such as Ginkgo biloba extract.
The decoding of the human genome has completely changed our views on medicine. Beyond sequencing, tools of the postgenomic era may lead to a better understanding of various therapies, especially those with a complex effect on numerous cellular components and functions. The development of high-density oligonucleotide microarrays led to pioneer studies on the multiple gene expression effects exhibited by Ginkgo biloba extract EGb 761, changing traditional pharmacology and medicine concepts. Instead of studying a simple gene or protein, a global investigation of all genes or proteins at once can give insights of the complexity of biological systems.
Christen
Yves
Y
Beaufour Ipsen, Paris, France. yves.christen@beaufour-ipsen.com
Olano-Martin
Estibaliz
E
Packer
Lester
L
D005786:Gene Expression Regulation / Q000187:drug effects; D020441:Ginkgo biloba; D020411:Oligonucleotide Array Sequence Analysis; D010936:Plant Extracts / Q000032:analysis* / Q000737:chemistry* / Q000235:genetics / Q000494:pharmacology; D000096983:Ginkgo Extract
D010936:Plant Extracts; C063170:Ginkgo biloba extract; D000096983:Ginkgo Extract