Normal splenic volume in adults by computed tomography.
OBJECTIVE
The purpose of the present study was to examine variations in spleen size in adults.


METHODS
The spleen volume was measured by computed tomography in 150 healthy donors for liver transplantation. The correlations between spleen volume and age, gender, body weight and body surface area were analyzed.


RESULTS
The mean volume of the spleen was 112 cm3, ranging from 32 to 209 cm3. The spleen volume significantly correlated with age (R = 0.36, p = 0.0002), but not with body weight or surface area. Gender did not influence the variation in spleen size.


CONCLUSIONS
A crude normal range stratified by age should provide useful information in the diagnosis of splenomegaly.
Kaneko
Junichi
J
Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Sugawara
Yasuhiko
Y
Matsui
Yuichi
Y
Ohkubo
Takao
T
Makuuchi
Masatoshi
M
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D013154:Spleen / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed