Proteomic analysis in the neurosciences.
Proteomics is a field of study directed toward providing a comprehensive view of the characteristics and activity of every cellular protein. Rapid innovations in the core technologies required to characterize proteins on a global scale are poised to bring about a comprehensive understanding of how dynamic changes in protein expression, post-translational modification, and function affect complex signaling and regulatory networks. These advances have significant implications for understanding the multitude of pathways that govern behavior and cognition and the response of the nervous system to injury and disease.
Morrison
Richard S
RS
Neurological Surgery, University of Washington School of Medicine, Seattle, Washington 98195-6470, USA. yael@u.washington.edu
Kinoshita
Yoshito
Y
Johnson
Mark D
MD
Uo
Takuma
T
Ho
Joseph T
JT
McBee
Joshua K
JK
Conrads
Thomas P
TP
Veenstra
Timothy D
TD
D000818:Animals; D016678:Genome; D015894:Genome, Human; D006801:Humans; D007554:Isotopes / Q000378:metabolism; D015394:Molecular Structure; D009420:Nervous System / Q000378:metabolism* / Q000473:pathology; D019636:Neurodegenerative Diseases / Q000378:metabolism; D009488:Neurosciences; D011506:Proteins / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D040901:Proteomics
D007554:Isotopes; D011506:Proteins