title: The use of remifentanil for bloodless surgical field during vertebral disc resection.
abstract: BACKGROUND
  A short hospital stay is nowadays desirable and affordable for a wide range of surgical pathology, respecting safety of care and home discharge. In the present study, the Authors investigated the use of TIVA with propofol/remifentanil during microsurgical vertebral disc resection to maintain a controlled vascular hypotension for bloodless surgical field aiming to reduce the operating time and consequently recovery room length of stay and morbility related to anaesthesia.
  
  
  METHODS
  The study took place in a 300 bed Orthopaedics hospital over a period of 3 months and 50 ASA I-II patients were enrolled in this trial; further data are presented for comparison of 50 ASA I-II patients homogeneous for age and sex to the studied population, operated under a standard TIVA with propofol and boluses of fentanyl. Duration of anaesthesia and surgery, time for awakening after cessation of TIVA, incidence of postoperative nausea and vomiting (PONV), amount and quality of postoperative analgesia, length of stay in the recovery room are reported in statistical presentation.
  
  
  RESULTS
  Time of surgery and anaesthesia were reduced in the remifentanil group compared with the fentanyl group, thanks to an easily reachable and durable state of controlled hypotension in the first group without the use of any other drug. The recovery profile was shorter in the remifentanil group the drug being rapidly metabolised by plasma cholinesterase.
  
  
  CONCLUSIONS
  No difference occurred between the two groups regarding quality and amount of postoperative analgesia, while PONV presented more in the fentanyl group and shivering more in the remifentanil group.
authors.affiliation: Anaesthetics and ICU Department, Orthopaedics Hospital F. Scalabrino (IOMI), Messina, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Chillemi
authors.forename: D
authors.initials: D
authors.lastname: Sinardi
authors.forename: A
authors.initials: A
authors.lastname: Marino
authors.forename: G
authors.initials: G
authors.lastname: Mantarro
authors.forename: R
authors.initials: R
authors.lastname: Campisi
mesh_terms: D000328:Adult; D000556:Ambulatory Surgical Procedures; D000771:Anesthesia, Intravenous; D018686:Anesthetics, Intravenous; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D005260:Female; D005283:Fentanyl; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D010149:Postoperative Pain / Q000188:drug therapy / Q000453:epidemiology; D010880:Piperidines; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology; D000077208:Remifentanil
chemical_list: D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil; D005283:Fentanyl