title: Nitric oxide photorelease from ruthenium salen complexes in aqueous and organic solutions.
abstract: The complexes [Ru(salen)(NO)Cl] and [Ru(salen)(NO)(H(2)O)](+) were shown to release the nitrosyl ligand as nitric oxide upon exposure to visible light in organic and aqueous solutions respectively, by means of UV-visible, EPR, and FTIR spectroscopies. The former was prepared by a new synthetic route and had its structure determined by single-crystal X-ray diffraction. A crystal of the dichloromethane solvate is orthorhombic, space group Fdd2 (No. 43) and formula C(16)H(14)ClN(3)O(3)Ru.CH(2)Cl(2), with Z = 16 and cell parameters a = 25.489(4), b = 33.435(4), and c = 9.3716(9) A. The electronic absorption spectra of the complexes were calculated using the INDO/S method. The water-soluble complex is a potential drug for antitumoral phototreatment.
authors.affiliation: Departamento de Química, Centro Politécnico, Universidade Federal do Paraná, Caixa Postal 19081, CEP 81531990, Curitiba-PR, Brazil.
authors.forename: Jeane
authors.initials: J
authors.lastname: Bordini
authors.forename: David L
authors.initials: DL
authors.lastname: Hughes
authors.forename: Joaquim Delphino
authors.initials: JD
authors.lastname: Da Motta Neto
authors.forename: Carlos Jorge
authors.initials: CJ
authors.lastname: da Cunha
mesh_terms: D018360:Crystallography, X-Ray; D004563:Electrochemistry; D004578:Electron Spin Resonance Spectroscopy; D005029:Ethylenediamines / Q000737:chemistry*; D007700:Kinetics; D008958:Models, Molecular; D009569:Nitric Oxide / Q000737:chemistry*; D010777:Photochemistry; D011789:Quantum Theory; D017975:Ruthenium Compounds / Q000737:chemistry*; D012996:Solutions; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D005029:Ethylenediamines; D017975:Ruthenium Compounds; D012996:Solutions; D009569:Nitric Oxide; C011452:disalicylaldehyde ethylenediamine