title: [Characteristics and indications of gabapentin].
abstract: Gabapentin is a drug that shares a similar structure to that of GABA, although its mechanism of action cannot be explained solely by a direct gaba mimetic effect. It is well absorbed when administered orally and displays linear kinetics up to doses of 1,800 mg/day. It is been found to be effective both in added therapy and in mono therapy, and is particularly useful in special populations like the elderly and children, as well as patients suffering from liver diseases. Its safety profile and the absence of interactions make it a suitable drug for the treatment of recently diagnosed epilepsies, both in mono therapy and in bi therapy.
authors.affiliation: Servicio de Neurología, Hospital General Universitario de Valencia, Valencia, España. med001942@saludalia.com
authors.forename: J
authors.initials: J
authors.lastname: Sancho-Rieger
mesh_terms: D000085:Acetates / Q000494:pharmacology / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000588:Amines; D000927:Anticonvulsants / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D003509:Cyclohexanecarboxylic Acids; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000188:drug therapy*; D000077206:Gabapentin; D006801:Humans; D008875:Middle Aged; D005680:gamma-Aminobutyric Acid
chemical_list: D000085:Acetates; D000588:Amines; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin