title: Immediate early gene expression in the visual cortex of normal and dark reared cats: differences between fos and egr-1.
abstract: Northern blotting indicated that the level of induced fos was higher in normal than dark reared cat visual cortex (VC) at 5 weeks of age, comparable at 10 weeks, and higher in dark reared than normal cat visual cortex at 20 weeks. Fos egr-1, induction was higher in dark reared visual cortex at all ages. Thus, dark rearing has similar effects on fos, but not egr-1, expression as it has on physiological neuronal plasticity during the VC critical period.
authors.affiliation: Department of Anatomical Sciences and Neurobiology, University of Louisville, School of Medicine, 500 South Preston Street, Louisville, KY 40202, USA. george.mower@louisville.edu
authors.forename: George D
authors.initials: GD
authors.lastname: Mower
authors.forename: Irina V
authors.initials: IV
authors.lastname: Kaplan
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002415:Cats; D002454:Cell Differentiation / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics; D003623:Dark Adaptation / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental / Q000235:genetics*; D017781:Genes, Immediate-Early / Q000235:genetics*; D009473:Neuronal Plasticity / Q000235:genetics*; D009474:Neurons / Q000378:metabolism; D016760:Proto-Oncogene Proteins c-fos / Q000235:genetics; D012333:RNA, Messenger / Q000378:metabolism; D012683:Sensory Deprivation / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics; D014793:Visual Cortex / Q000254:growth & development* / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D016760:Proto-Oncogene Proteins c-fos; D012333:RNA, Messenger; D014157:Transcription Factors