title: Choroidal metastasis from medullary thyroid carcinoma in multiple endocrine neoplasia.
abstract: OBJECTIVE
  To report choroidal metastasis from medullary thyroid carcinoma in a patient with multiple endocrine neoplasia (MEN) type 2b.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  Medullary thyroid carcinoma developed in a 20-year-old woman and led to the diagnosis of MEN 2b. She had mucosal neuromas on the lips and tongue and prominent corneal nerves in both eyes. Right choroidal metastasis developed when she was 36 years of age.
  
  
  RESULTS
  The eye was treated with irradiation, but 9 months later the patient died of widespread metastases.
  
  
  CONCLUSIONS
  In patients with MEN type 2b, choroidal metastasis can develop from medullary thyroid carcinoma. Although fundus abnormalities typically do not occur with MEN 2b, choroidal metastasis from medullary thyroid carcinoma is a potential fundus finding.
authors.affiliation: Oncology Service Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: Jerry A
authors.initials: JA
authors.lastname: Shields
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
authors.forename: Noel
authors.initials: N
authors.lastname: Perez
mesh_terms: D000328:Adult; D018276:Carcinoma, Medullary / Q000473:pathology / Q000556:secondary*; D002830:Choroid Neoplasms / Q000473:pathology / Q000556:secondary*; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D018814:Multiple Endocrine Neoplasia Type 2b / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology*