Effects of low-dose OCs on weight in women with Central European nutritional habits and lifestyle.
The aim of the study was to evaluate the acceptance and tolerance of combined low-dose oral contraceptives (OCs) (containing 20 micro g ethinylestradiol and 75 micro g gestodene) in a cohort of Polish women, and to present a relationship between the use of combined OCs and changes in body weight. Changes in body weight with combined low-dose OC have not been demonstrated in placebo-controlled trials, nor were such trials performed in a population whose nutritional/dietary habits and lifestyle resemble that of the population of Poland. We performed the clinical study on a group of 800 patients living in several regions of Poland. Patients used the low-dose OC for a period of 6 months. They were assessed every third cycle of OC use (initial examination and examinations after three and six cycles of OC use). On the basis of this investigation, a relationship between OC use and weight gain was not found.
Lech
Medard M
MM
School of Public Health in the State Medical Center of Postgraduate Education, Warsaw, Poland. medardlech@poczta.onet.pl
Ostrowska
Lucyna
L
D000328:Adult; D015992:Body Mass Index; D003276:Contraceptives, Oral / Q000008:administration & dosage*; D004997:Ethinyl Estradiol / Q000008:administration & dosage; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008019:Life Style; D009652:Norpregnenes / Q000008:administration & dosage; D009747:Nutritional Physiological Phenomena; D011044:Poland; D015430:Weight Gain / Q000187:drug effects*
D003276:Contraceptives, Oral; D009652:Norpregnenes; C033273:Gestodene; D004997:Ethinyl Estradiol