Characterization of low molecular weight alkoxylated polymers using long column SFC/MS and an image analysis based quantitation approach.
The utility of low viscosity mobile phases and long chromatographic columns for complex polymer analysis is demonstrated. We use long column supercritical fluid chromatography/mass spectrometry (SFC/MS) with electrospray ionization (ESI) to characterize a variety of complex, low molecular weight polymers. When quantitative analysis is desired, the resulting three-dimensional (time, intensity, and mass-to-charge ratio [m/z]) data are converted to images. Custom image analysis software is used to detect and integrate peaks in arbitrarily defined regions of the time-m/z map. These integrated peak volumes can be used to quantitate distinct component classes of the polymer mixtures.
Pinkston
J David
JD
Miami Valley Laboratories, The Procter and Gamble Company, Cincinnati, Ohio 45253-8707, USA. pinkston.jd@pg.com
Marapane
Suresh B
SB
Jordan
Glenn T
GT
Clair
B David
BD