Synthesis and absolute configuration of a new 3,4-dihydro-beta-carboline-type alkaloid, 3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian Uña de Gato (Uncaria tomentosa).
The structure including the absolute configuration of a new glucoalkaloid, 3,4-dehydro-5(S)-5-carboxystrictosidine, isolated from Peruvian Uña de Gato (Cat's Claw, original plant: Uncaria tomentosa), was confirmed by synthesis starting from secologanin and L-tryptophan.
Kitajima
Mariko
M
Graduate School of Pharmaceutical Sciences, Chiba University, Japan.
Yokoya
Masashi
M
Takayama
Hiromitsu
H
Aimi
Norio
N
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D002243:Carbolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D020948:Cat's Claw / Q000737:chemistry*; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D008968:Molecular Conformation; D010568:Peru; D014748:Vinca Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification
D000470:Alkaloids; D002243:Carbolines; D026121:Indole Alkaloids; D014748:Vinca Alkaloids; C021093:strictosidine