title: Uterine leiomyoma after embolization by means of gelatin sponge particles alone: report of a case with histopathologic features.
abstract: We describe the histopathologic features of uterine leiomyoma after uterine artery embolization (UAE) in a 42-year-old woman. This patient, who was taking antiplatelet drugs for the treatment of cerebral disease, successfully underwent UAE using only gelatin sponge particles for a symptomatic uterine leiomyoma. Although menorrhagia improved moderately after the procedure, she underwent abdominal hysterectomy 11 months later because of recurrent uterine bleeding. Histopathology revealed that most of the area of the uterine leiomyoma was characterized by extensive coagulation necrosis, which support the positive result of the procedure. No significant abnormalities were noted in either the myometrium or endometrium, which also suggested that UAE using only gelatin sponge particles is an appropriate procedure to preserve the uterus. The histologic and radiologic features of this case are discussed. To the best of our knowledge, this is the first reported case of uterine leiomyoma after UAE using only gelatin sponge particles as a primary embolic agent.
authors.affiliation: Department of Radiology, Saiseikai Shiga Hospital, Ritto, Shiga, Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Katsumori
authors.forename: Masamichi
authors.initials: M
authors.lastname: Bamba
authors.forename: Tadao K
authors.initials: TK
authors.lastname: Kobayashi
authors.forename: Suzuko
authors.initials: S
authors.lastname: Moritani
authors.forename: Mamoru
authors.initials: M
authors.lastname: Urabe
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Nakajima
authors.forename: Tadashi
authors.initials: T
authors.lastname: Mihara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sugihara
mesh_terms: D000328:Adult; D004621:Embolization, Therapeutic; D005260:Female; D005781:Gelatin Sponge, Absorbable; D006801:Humans; D007044:Hysterectomy; D007889:Leiomyoma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D008595:Menorrhagia / Q000628:therapy; D009336:Necrosis; D011859:Radiography; D014594:Uterine Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D014599:Uterus / Q000098:blood supply / Q000473:pathology