Development of a diffusive sampling method for determination of methyl isocyanate in air.
A diffusive sampling method for determination of methyl isocyanate in air has been developed. A glass fibre filter impregnated with 1-(2-methoxyphenyl)piperazine in a commercially available diffusive sampling device was used to collect methyl isocyanate and the derivative formed was analysed with LC-MS/MS. The sampling rate was determined to be 15.6 ml min(-1), with a relative standard deviation of 7.3%. The sampler was validated for sampling periods from 15 min to 8 h, for relative humidities from 20% to 80% and for concentrations from I to 46 microg m(-3). A field validation was also made and the diffusive sampling results showed no difference compared to a pumped reference method. The impregnated filters have to be stored apart from the diffusive sampler housing and loaded into the sampler prior to each sampling.
von Zweigbergk
Peter
P
National Institute for Working Life, Umeå, Sweden. peter.von.zweigbergk@niwl.se
Lindahl
Roger
R
Ostin
Anders
A
Ekman
Jenny
J
Levin
Jan-Olof
JO
D016902:Air Pollution, Indoor / Q000032:analysis*; D000986:Antisickling Agents / Q000032:analysis*; D004058:Diffusion; D004784:Environmental Monitoring / Q000295:instrumentation*; D006801:Humans; D017953:Isocyanates / Q000032:analysis*; D016273:Occupational Exposure; D012016:Reference Values; D013048:Specimen Handling
D000986:Antisickling Agents; D017953:Isocyanates; C008461:methyl isocyanate