title: Rheumatoid arthritis of the cervical spine: current techniques for management.
abstract: The incidence of rheumatoid arthritis in the European and North American population is significant. Rheumatoid arthritis can result in serious damage to the cervical spine and the central neuraxis, ranging from mild instability to myelopathy and death. Aggressive conservative care should be established early. The treating physician should not be lulled into a false sense of security by reports suggesting that cervical subluxations are typically asymptomatic [76-78]. Gradual spinal cord compression can result in severe neurologic deficits that may be irreversible despite appropriate surgical intervention when applied too late. [figure: see text] The treatment of rheumatoid disease in the cervical spine is challenging. Many details must be considered when diagnosing and attempting to institute a treatment plan, particularly surgical treatment. The pathomechanics may result in either instability or ankylosis. The superimposed deformities may be either fixed or mobile. The algorithm suggested by the authors can be used to navigate through the numerous details that must be considered to formulate a reasonable surgical plan. Although these patients are [figure: see text] frail, an "aggressive" surgical solution applied in a timely fashion yields better results than an incomplete or inappropriate surgical solution applied too late. When surgical intervention is anticipated, it should be performed before the development of severe myelopathy. Patients who progress to a Ranawat III-B status have a much higher morbidity and mortality rate associated with surgical intervention than do patients who ambulate. Although considered aggressive by some, "prophylactic" stabilization and fusion of a [figure: see text] relatively flexible, moderately deformed spine before the onset of severe neurologic symptoms may be reasonable. This approach ultimately may serve the patient better than "observation" if the patient is slowly drifting into a severe spinal deformity or shows signs of early myelopathy or paraparesis.
authors.affiliation: Department of Surgical Neurology, National Hospital for Neurology and Neurosurgery, Queens Square, London, UK.
authors.forename: Adrian T H
authors.initials: AT
authors.lastname: Casey
authors.forename: H Alan
authors.initials: HA
authors.lastname: Crockard
authors.forename: Jean
authors.initials: J
authors.lastname: Pringle
authors.forename: Michael F
authors.initials: MF
authors.lastname: O'Brien
authors.forename: John M
authors.initials: JM
authors.lastname: Stevens
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography; D013122:Spinal Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*