title: Microbiology of chronic suppurative otitis media in Singapore.
abstract: The objective of the study was to study the microflora and the antibiograms of patients with chronic suppurative otitis media (CSOM) in Singapore. Ninety patients with CSOM were prospectively studied. They had chronic ear discharge and had not received antibiotics for the previous five days. Swabs were taken, and cultured for bacteria. Antibiotic testing was done using modified Kirby Bauer disk diffusion method. In addition to the usual antibiotics, the three most common topically available antibiotics (chloramphenicol, gentamicin and neomycin) were tested. There were 135 positive cultures for organisms from the 90 patients. The most common causal organisms isolated were Pseudomonas aeruginosa (33.3%) and Staphylococcus aureus (33.3%) followed by coagulase negative Staphylococcus (21.1%). Fungi accounted for 8.8% of isolates while 6.6% were anaerobes. Of the three antibiotics commonly available as topical eardrops, gentamicin has the highest susceptibility rate (82.6%), followed by neomycin (67.8%) and chloramphenicol (62.8%).
authors.affiliation: Department of Otolaryngology, Singapore General Hospital, Singapore. a_loy@hotmail.com
authors.forename: A H C
authors.initials: AH
authors.lastname: Loy
authors.forename: A L
authors.initials: AL
authors.lastname: Tan
authors.forename: P K S
authors.initials: PK
authors.lastname: Lu
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000188:drug therapy / Q000382:microbiology*; D011446:Prospective Studies; D011550:Pseudomonas aeruginosa; D017678:Sex Distribution; D013211:Staphylococcus aureus
chemical_list: D000900:Anti-Bacterial Agents