Prevention of early mutans streptococci transmission in infants by professional tooth cleaning and chlorhexidine varnish treatment of the mother.
Mutans streptococci (MS) are transmitted in early childhood from the mother to the infant, mostly by saliva. This study evaluated the influence of chlorhexidine (CHX) varnish-mediated suppression of MS in mothers with high salivary MS counts on the frequency of MS colonization in their children at 2 years of age. Professional tooth cleaning followed by CHX varnish application in 16 mothers with high salivary MS counts resulted in a significantly lower number of MS-colonized infants at 2 years of age when compared to a control group of 13 untreated mother-child pairs with high maternal salivary MS levels. The frequency of MS colonization in the CHX-treated group was not significantly different from the one found in a negative control group of 15 mother-child pairs with low maternal salivary MS levels.
Gripp
Vivian C
VC
Department of Conservative Dentistry and Periodontology, School of Dental Medicine, University of Tübingen, Germany.
Schlagenhauf
Ulrich
U
D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D016009:Chi-Square Distribution; D002710:Chlorhexidine / Q000008:administration & dosage*; D015169:Colony Count, Microbial; D003777:Dental Prophylaxis; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D009035:Mothers; D010150:Paint; D012463:Saliva / Q000382:microbiology; D018709:Statistics, Nonparametric; D013290:Streptococcal Infections / Q000517:prevention & control* / Q000635:transmission*; D013295:Streptococcus mutans / Q000187:drug effects
D000891:Anti-Infective Agents, Local; D002710:Chlorhexidine