title: Systemic lupus erythematosus in childhood.
abstract: Systemic lupus erythematosus is a disease of immune dysregulation that strikes approximately 1 in 2000 individuals. The usual patient is a young woman of child-bearing age; however, this illness affects patients of all ages, ethnic backgrounds, and both sexes. Twenty percent of all cases of lupus are diagnosed during the first two decades of life. Perhaps the most essential point in treating a child with lupus is to be aware and concerned about how to deliver treatment to a patient in the middle of their physical, intellectual, and emotional development.
authors.affiliation: Division of Immunology/Rheumatology, Department of Pediatrics, Children's Memorial Hospital, Northwestern University, Chicago, IL, USA.
authors.forename: Marisa
authors.initials: M
authors.lastname: Klein-Gitelman
authors.forename: Andreas
authors.initials: A
authors.lastname: Reiff
authors.forename: Earl D
authors.initials: ED
authors.lastname: Silverman
mesh_terms: D000293:Adolescent; D000974:Antibodies, Antinuclear / Q000097:blood; D001168:Arthritis / Q000209:etiology; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control; D002648:Child; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D008181:Lupus Nephritis / Q000209:etiology; D020945:Lupus Vasculitis, Central Nervous System / Q000209:etiology; D008297:Male; D009140:Musculoskeletal Diseases / Q000209:etiology; D012737:Sex Factors; D014611:Vaccination; D014777:Virus Diseases / Q000209:etiology / Q000517:prevention & control
chemical_list: D000974:Antibodies, Antinuclear