The synthesis of deoxyfusapyrone. 1. An approach to the pyrone moiety.
An effective synthesis of the C1-C10 component of deoxyfusapyrone has been achieved that will allow for the synthesis of both the (R) and (S) form of the C-8 chiral center starting from optically pure (+)- and (-)-3,3-dimethyl-2-hydroxy-gammalactone (pantolactone).
Organ
Michael G
MG
Department of Chemistry, York University, 4700 Keele Street, Toronto, Ontario, Canada M3J 1P3. organ@yorku.ca
Wang
Junquan
J
D003500:Cyclization; D003653:Decarboxylation; D015394:Molecular Structure; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
D011753:Pyrones; C088398:deoxyfusapyrone