title: Brine shrimp lethality bioassay of selected Indian medicinal plants.
abstract: Ethanolic extracts of six Indian medicinal plants, piperine, guggulsterone E and guggulsterone Z were tested for cytotoxicity using brine shrimp lethality test. Piper longum showed most potent cytotoxic activity. Piperine, guggulsterone E and guggulsterone Z showed potent activity with LC(50) 2.4, 8.9 and 4.9, respectively.
authors.affiliation: Bioassay Unit, Research & Development Centre, Natural Remedies Pvt Ltd, Plot No 5B, Veerasandra Indl Area, Hosur Road, Bangalore 561 229, India.
authors.forename: R
authors.initials: R
authors.lastname: Padmaja
authors.forename: P C
authors.initials: PC
authors.lastname: Arun
authors.forename: D
authors.initials: D
authors.lastname: Prashanth
authors.forename: M
authors.initials: M
authors.lastname: Deepak
authors.forename: A
authors.initials: A
authors.lastname: Amit
authors.forename: M
authors.initials: M
authors.lastname: Anjana
mesh_terms: D000818:Animals; D001156:Artemia / Q000187:drug effects*; D007194:India; D007928:Lethal Dose 50; D008519:Medicine, Traditional; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000145:classification*
chemical_list: D010936:Plant Extracts