title: [Secondary pulmonary alveolar proteinosis associated with myelodysplastic syndrome].
abstract: A 51-year-old man with myelodysplastic syndrome (MDS) was admitted to our hospital because of dyspnea on exertion in December 1999. Chest radiography showed ground-glass shadows in the middle and lower fields of both lungs, and chest computed tomography revealed a typical "crazy paving appearance". The bronchoalveolar lavage fluid was milky in appearance, and so secondary pulmonary alveolar proteinosis associated with MDS was diagnosed. Because there was no need to treat his MDS, we twice performed whole-lung lavage under general anesthesia in January and February 2000. The treatments were effective, and his abnormal chest radiography findings, laboratory data and pulmonary function were normalized. This was a rare case of secondary pulmonary alveolar proteinosis associated with MDS successfully treated with whole-lung lavage.
authors.affiliation: Second Department of Internal Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan1-20-1 Handayama, Hamamatsu, Shizuoka, Japan, 431-3192.
authors.forename: Koshi
authors.initials: K
authors.lastname: Yokomura
authors.forename: Kingo
authors.initials: K
authors.lastname: Chida
authors.forename: Takafumi
authors.initials: T
authors.lastname: Suda
authors.forename: Seiichi
authors.initials: S
authors.lastname: Miwa
authors.forename: Hideki
authors.initials: H
authors.lastname: Nakano
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Kuwata
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Suzuki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Matsuda
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Asada
authors.forename: Yutaro
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Naoki
authors.initials: N
authors.lastname: Inui
authors.forename: Masahiro
authors.initials: M
authors.lastname: Shirai
authors.forename: Kazuya
authors.initials: K
authors.lastname: Suzuki
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D018893:Bronchoalveolar Lavage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications*; D011649:Pulmonary Alveolar Proteinosis / Q000209:etiology / Q000628:therapy*