title: Pediatric localized amyloidosis in mesopharynx.
abstract: Primary localized amyloidosis of the mesopharynx is rare. We present the case of a 12-year-old girl; as far as we are aware, our case is the third pediatric case in the English literature. Her chief complaint was a pharyngeal mass identified by the health examination at primary school. Physical examination revealed a mass in the faucial tonsil. Histologically, the lesion was composed of deposition of amyloid and chronic inflammatory cell infiltration. Immunohistochemical studies showed that the lesion was positive for amyloid P component (AP) and negative for amyloid L (AL). No treatments were applied, because she had no symptoms. During the observation period of 24 months, the mesopharyngeal mass showed no remarkable change.
authors.affiliation: Department of Otolaryngology, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Japan. masahir@qd5.so-net.ne.jp
authors.forename: Masahiro
authors.initials: M
authors.lastname: Takahashi
authors.forename: Hideki
authors.initials: H
authors.lastname: Matsuda
authors.forename: Keiko
authors.initials: K
authors.lastname: Ito
authors.forename: Takaaki
authors.initials: T
authors.lastname: Ito
authors.forename: Mamoru
authors.initials: M
authors.lastname: Tsukuda
mesh_terms: D000686:Amyloidosis / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010608:Pharyngeal Diseases / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D000683:Serum Amyloid P-Component / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D000683:Serum Amyloid P-Component