title: Stereoselective synthesis of beta-substituted phenylalanine-beta-phenylisoserine-derived tripeptides using N-cinnamoyl-L-proline as template: synthesis of structural analogues of HIV protease inhibitors.
abstract: N-Cinnamoyl-L-proline can be used as a template on which beta-substituted phenylalanine and beta-phenylisoserine residues can be synthesized leading to tripeptide derivatives as structural analogues of HIV protease inhibitors.
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, India.
authors.forename: Biswajit
authors.initials: B
authors.lastname: Saha
authors.forename: Jyoti Prokash
authors.initials: JP
authors.lastname: Nandy
authors.forename: Shalini
authors.initials: S
authors.lastname: Shukla
authors.forename: Iffat
authors.initials: I
authors.lastname: Siddiqui
authors.forename: Javed
authors.initials: J
authors.lastname: Iqbal
mesh_terms: D002934:Cinnamates / Q000138:chemical synthesis* / Q000737:chemistry*; D018360:Crystallography, X-Ray; D017320:HIV Protease Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry*; D010649:Phenylalanine / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D012694:Serine / Q000031:analogs & derivatives* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D002934:Cinnamates; D017320:HIV Protease Inhibitors; C484915:N-cinnamoyl-L-proline; D010455:Peptides; D012694:Serine; D010649:Phenylalanine; C010286:beta-phenylisoserine; D011392:Proline