title: IgE-mediated urticaria from formaldehyde in a dental root canal compound.
abstract: A patient had suffered twice from an acute urticaria after treatment with two different dental root canal compounds (RCC). Skin prick tests with the single components and formaldehyde 1%aq. were positive to formaldehyde 1%aq., but irritant with formaldehydeRCC. Specific IgE to formaldehyde were positive. Patch tests were positive to formaldehydeRCC only. In the literature 28 patients with immediate symptoms to formaldehyde containing RCC have been described.
authors.affiliation: Dept. of Dermatology, University Hospital, Basel, Switzerland.
authors.forename: Esra
authors.initials: E
authors.lastname: Tas
authors.forename: Martin
authors.initials: M
authors.lastname: Pletscher
authors.forename: Andreas J
authors.initials: AJ
authors.lastname: Bircher
mesh_terms: D000328:Adult; D000368:Aged; D000918:Antibody Specificity / Q000187:drug effects / Q000276:immunology; D003429:Cross Reactions / Q000187:drug effects / Q000276:immunology; D003786:Dental Pulp Cavity / Q000187:drug effects*; D004342:Drug Hypersensitivity / Q000209:etiology; D005260:Female; D005404:Fixatives / Q000009:adverse effects*; D005557:Formaldehyde / Q000009:adverse effects*; D006801:Humans; D007073:Immunoglobulin E / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D012387:Root Canal Filling Materials / Q000009:adverse effects*; D012390:Root Canal Therapy / Q000009:adverse effects*; D012882:Skin Tests; D014581:Urticaria / Q000139:chemically induced*
chemical_list: D005404:Fixatives; D012387:Root Canal Filling Materials; D005557:Formaldehyde; D007073:Immunoglobulin E