Czech miner studies of lung cancer risk from radon.
Epidemiological evidence of lung cancer risk from radon is based mainly on studies of miners. Two such studies among Czech uranium miners were established in 1970 and 1980. A subcohort of 5002 miners and a nested-in case-control study contribute to a joint European project. In this paper, the subcohort of miners with 495 lung cancers is described. The excess relative risk depends linearly on cumulative exposure incurred more than 5 years before. The relative effect from exposures in the distant past decreases by 62% per decade. Simultaneously, the excess relative risk is lower by 43% per decade in dependence on age at exposure. The effect of smoking, partly analysed in the study, suggests a twofold elevation in the relative risk coefficient among non-smokers, but this difference is not significant.
Tomásek
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National Radiation Protection Institute, Prague, Czech Republic.
D000328:Adult; D000368:Aged; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000396:Air Pollutants, Radioactive / Q000009:adverse effects*; D016022:Case-Control Studies; D015331:Cohort Studies; D018153:Czech Republic; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D008906:Mining; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D009784:Occupational Diseases / Q000209:etiology*; D016273:Occupational Exposure; D011829:Radiation Dosage; D011886:Radon / Q000009:adverse effects*; D012307:Risk Factors; D014501:Uranium
D000395:Air Pollutants, Occupational; D000396:Air Pollutants, Radioactive; D014501:Uranium; D011886:Radon