title: A stereodivergent approach to substituted 4-hydroxypiperidines.
abstract: A stereodivergent route toward both diastereomeric forms of functionalized 4-hydroxypiperidines has been successfully developed. This route involves biocatalytic generation of the enantiopure starting materials followed by functionalization via N-acyliminium ion-mediated CC-bond formation.
authors.affiliation: Institute of Molecular Chemistry, University of Amsterdam, Nieuwe Achtergracht 129, The Netherlands.
authors.forename: Mandy K S
authors.initials: MK
authors.lastname: Vink
authors.forename: Christien A
authors.initials: CA
authors.lastname: Schortinghuis
authors.forename: Jordy
authors.initials: J
authors.lastname: Luten
authors.forename: Jan H
authors.initials: JH
authors.lastname: Van Maarseveen
authors.forename: Hans E
authors.initials: HE
authors.lastname: Schoemaker
authors.forename: Henk
authors.initials: H
authors.lastname: Hiemstra
authors.forename: Floris P J T
authors.initials: FP
authors.lastname: Rutjes