title: Neural conservation in skull base surgery.
abstract: Surgical treatment of lesions of the skull base carries significant risk to the functioning of the cerebral hemispheres, the brain stem and the cranial nerves. This risk is due both, to problems associated with maintaining an adequate blood flow while exposing and removing the tumor and to direct or indirect trauma to the brain, perineural tissues and cranial nerves. These risks may be reduced if information about possible implications of surgical maneuvers on the cerebral blood flow and on the function of the patients central nervous system and cranial nerves is available and can be monitored during surgery of the skull base. The use of electromyographic neuromonitoring for the facial nerve and of BERA-monitoring for the auditory nerve have been described and are now standard methods to achieve these goals. In acoustic tumors in the last several years beside preservation of the function of the facial nerve hearing preservation especially in small tumors has been one of the primary goals in acoustic neuroma surgery. Computer assisted surgery and intraoperative imaging for lateral skull base surgery are still in their infancy but promise to allow further improvement of neural conservation.
authors.affiliation: Department of Ear-Nose-Throat, University of Minz Medical School, Langenbeckstrasse 1, 55131 Mainz, Germany. mann@hno.klinik.uni-mainz.de
authors.forename: W J
authors.initials: WJ
authors.lastname: Mann
authors.forename: J
authors.initials: J
authors.lastname: Maurer
authors.forename: N
authors.initials: N
authors.lastname: Marangos
mesh_terms: D001921:Brain / Q000098:blood supply; D004576:Electromyography; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005154:Facial Nerve / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D016343:Monitoring, Intraoperative; D013506:Otologic Surgical Procedures / Q000379:methods*; D016879:Salvage Therapy / Q000379:methods*; D019292:Skull Base Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery*