title: Design, synthesis, and application of peptide secondary structure mimetics.
abstract: The secondary structure peptidomimetic approach is a rational way to develop novel nonpeptide pharmaceutical agents based upon biologically significant proteinaceous leads. A part of this approach elaborated in this laboratory over the past ten years is reviewed along with the recent developments in this field.
authors.affiliation: Pacific Northwest Research Institute, 720 Broadway, Seattle, WA 98122, USA.
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Eguchi
authors.forename: Michael
authors.initials: M
authors.lastname: Kahn
mesh_terms: D018360:Crystallography, X-Ray; D015195:Drug Design; D008958:Models, Molecular; D018716:Molecular Mimicry; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D017433:Protein Structure, Secondary
chemical_list: D010455:Peptides