Fondaparinux sodium does not cross the placental barrier: study using the in-vitro human dually perfused cotyledon model.
Lagrange
Fabrice
F
Department of Pharmacology, Victor Segalen Bordeaux University, Bordeaux, France.
Brun
Jean-Luc
JL
Vergnes
Marie Christine
MC
Paolucci
Francis
F
Nadal
Teresa
T
Leng
Jean-Joel
JJ
Saux
Marie Claude
MC
Bannwarth
Bernard
B
D000328:Adult; D017984:Enoxaparin / Q000493:pharmacokinetics*; D065427:Factor Xa Inhibitors; D005260:Female; D005343:Fibrinolytic Agents / Q000493:pharmacokinetics*; D000077425:Fondaparinux; D006801:Humans; D066298:In Vitro Techniques; D008431:Maternal-Fetal Exchange; D008954:Models, Biological; D010920:Placenta / Q000098:blood supply*; D011134:Polysaccharides / Q000493:pharmacokinetics*; D011247:Pregnancy
D017984:Enoxaparin; D065427:Factor Xa Inhibitors; D005343:Fibrinolytic Agents; D011134:Polysaccharides; D000077425:Fondaparinux