title: MRI findings including gadolinium-enhanced dynamic studies of malignant, mixed mesodermal tumors of the uterus: differentiation from endometrial carcinomas.
abstract: Our objective was to evaluate the usefulness of MRI including dynamic study in differentiating malignant, mixed mesodermal tumor (MMMT) from endometrial carcinoma (EC). The MR images were reviewed in 4 patients with histologically confirmed MMMT and 11 patients with EC. Flow voids inside and/or around the tumors were seen in 2 patients with MMMT but not in any EC cases. In dynamic studies, all 4 patients with MMMT showed areas of early and persistent marked enhancement similar to that of the myometrium, mixed with areas of gradual and delayed marked enhancement. The portions showing early and persistent enhancement histologically corresponded to predominantly sarcomatous components with prominent vascularity. Ten of 11 ECs did not show such enhancement and only one showed a rapid enhancement in the early phase which was diminished in the delayed phase. The MR imaging with a gadolinium-enhanced dynamic study seems to be useful in differentiating MMMT from EC.
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, Iseigaoka 1-1, Yahatanisi-ku, Kitakyushu-shi 807-8555, Japan. ogurieye@med.uoeh-u.ac.jp
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ohguri
authors.forename: Takatoshi
authors.initials: T
authors.lastname: Aoki
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Katsumi
authors.initials: K
authors.lastname: Nakamura
authors.forename: Hajime
authors.initials: H
authors.lastname: Nakata
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Matsuura
authors.forename: Masamichi
authors.initials: M
authors.lastname: Kashimura
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D003287:Contrast Media; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000175:diagnosis*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018199:Mixed Tumor, Mesodermal / Q000175:diagnosis*; D014594:Uterine Neoplasms / Q000175:diagnosis*; D014599:Uterus / Q000473:pathology
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA