title: The efficacy of dentine adhesive to sclerotic dentine.
abstract: OBJECTIVE
  To evaluate the effect of a dentine bonding system to sclerotic dentine in comparison with normal dentine.
  
  
  METHODS
  The efficacy of the dentine bonding system to sclerotic dentine was examined by measuring wall-to-wall polymerization contraction gap width. The dentine cavity wall was pretreated with an experimental dentine bonding system with and without a dentine primer. The dentine primer was glyceryl mono-methacrylate (Blemmer GLM, NOF Corp., Tokyo, Japan) (GM), which contained esterified methacrylate with a polyvalent alcohol, which is similar to 2-HEMA. The structure of sclerotic dentine and the changes to that structure caused by etching were observed using a scanning electron microscope (SEM).
  
  
  RESULTS
  With GM priming, complete marginal integrity was obtained regardless of the type of dentine. Without GM priming, complete marginal integrity was obtained in half of the specimens of the sclerotic dentine, and was not obtained in any of the specimens of normal dentine. In the SEM study, the structure of sclerotic dentine was considered to be viable for adhesion. However, this was not the case when etched with phosphoric acid.
  
  
  CONCLUSIONS
  It was concluded that sclerotic dentine had a clear advantage over normal dentine with regard to the adaptation of resin composites. Therefore the structure of sclerotic dentine possesses a naturally derived structure to which a primer may attach. Sclerotic dentine is part of the body's natural defenses and should be preserved. It should not be exposed to acid etching which would damage its structure.
authors.affiliation: Department of Operative Dentistry, School of Dentistry, Showa University, 2-1-1 Kitasenzoku, Ohta-Ward, Tokyo, Japan. mizuho@senzoku.showa-u.ac.jp
authors.forename: Mizuho
authors.initials: M
authors.lastname: Kusunoki
authors.forename: Kazuo
authors.initials: K
authors.lastname: Itoh
authors.forename: Hisashi
authors.initials: H
authors.lastname: Hisamitsu
authors.forename: Sadao
authors.initials: S
authors.lastname: Wakumoto
mesh_terms: D000134:Acid Etching, Dental / Q000009:adverse effects; D003188:Composite Resins / Q000737:chemistry; D001840:Dental Bonding; D018772:Dental Marginal Adaptation; D003804:Dentin / Q000187:drug effects / Q000648:ultrastructure; D003806:Dentin Permeability / Q000187:drug effects; D003809:Dentin, Secondary / Q000187:drug effects / Q000648:ultrastructure; D017220:Dentin-Bonding Agents / Q000737:chemistry; D004492:Edetic Acid / Q000009:adverse effects; D005989:Glycerides; D006801:Humans; D008689:Methacrylates; D008855:Microscopy, Electron, Scanning; D010756:Phosphoric Acids / Q000009:adverse effects; D019279:Resin Cements / Q000737:chemistry; D013499:Surface Properties / Q000187:drug effects
chemical_list: D003188:Composite Resins; D017220:Dentin-Bonding Agents; D005989:Glycerides; D008689:Methacrylates; D010756:Phosphoric Acids; D019279:Resin Cements; C074669:Clearfil Photo Bond; C074741:Silux Plus; C069750:glyceryl methacrylate; D004492:Edetic Acid; C030242:phosphoric acid