title: C-reactive protein should accelerate the diagnosis of bowel injury after gynecologic surgery.
abstract: OBJECTIVE
  To search for a marker that could aid in earlier diagnosis of bowel injury after gynecologic surgery.
  
  
  METHODS
  Retrospective case study with prospective controls (Canadian Task Force classification II-2).
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Fourteen women with bowel injuries and 50 controls with no postoperative complications.
  
  
  RESULTS
  Bowel injury occurred in 14 (2.4/1000) of 5901 gynecologic procedures. Of these, eight were recognized intraoperatively and treated immediately. In six women C-reactive protein levels were markedly increased (>100 mg/L) relative to control patients (p <0.0001).
  
  
  CONCLUSIONS
  Systematic postoperative assessment of C-reactive protein in patients at high risk for bowel injury may help identify this complication earlier in the postoperative period.
authors.affiliation: Department of Obstetrics and Gynecology, Hospital Antoine Beclere, Clamart, France.
authors.forename: C
authors.initials: C
authors.lastname: Rongières
authors.forename: V
authors.initials: V
authors.lastname: Gomel
authors.forename: O
authors.initials: O
authors.lastname: Garbin
authors.forename: H
authors.initials: H
authors.lastname: Fernandez
authors.forename: R
authors.initials: R
authors.lastname: Frydman
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis / Q000378:metabolism*; D016022:Case-Control Studies; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis* / Q000209:etiology; D007422:Intestines / Q000293:injuries*; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods; D007813:Laparotomy / Q000009:adverse effects / Q000379:methods; D008875:Middle Aged; D011183:Postoperative Complications / Q000097:blood / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011336:Probability; D011446:Prospective Studies; D012016:Reference Values; D012086:Reoperation; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013997:Time Factors
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein