title: The diagnosis of lichen-planus-like contact dermatitis to chlorpheniramine maleate.
abstract: In spite of the common use of the diagnostic category of lichen-planus-like contact dermatitis, we were unable to find established criteria for such a condition. An atypical distribution of otherwise typical lichen planus lesions is usually considered as a feature of a lichenoid eruption. When facing unusual or unexpected clinical features, it is always advisable to consider an adverse reaction to a medical intervention as a potential option. We report a lichen-planus-like eruption occurring after contact with a topical agent containing chlorpheniramine maleate. To our knowledge, this is the first reported case of lichen-planus-like contact dermatitis associated with chlorpheniramine maleate.
authors.affiliation: Department of Dermatology, Shimotsuga General Hospital, Fujimi-cho, Tochigi, Japan. krkuro@ceres.ocn.ne.jp
authors.forename: Kei
authors.initials: K
authors.lastname: Kuroda
authors.forename: Yuko
authors.initials: Y
authors.lastname: Hisanaga
mesh_terms: D000368:Aged; D018926:Anti-Allergic Agents / Q000009:adverse effects*; D002744:Chlorpheniramine / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000139:chemically induced / Q000175:diagnosis* / Q000188:drug therapy; D010328:Patch Tests; D011246:Pregnadienetriols / Q000627:therapeutic use; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D018926:Anti-Allergic Agents; D011246:Pregnadienetriols; C100065:flucloronide; D002744:Chlorpheniramine