title: Primary low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT)-type of the liver in a patient with hepatitis C virus infection.
abstract: We report a case of primary low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT)-type of the liver presenting as a solitary mass in a patient with hepatitis C virus infection. A 73-year-old male was referred to our hospital because of a solitary mass in the liver, which was identified by ultrasonography during a routine follow-up study for his hepatitis C virus carrier status. A fine-needle biopsy was performed and the mass was diagnosed as non-Hodgkin's lymphoma. A detailed investigation showed no evidence of lymphoma in other sites. Left lateral segmentectomy was performed. Histologic examination showed diffuse, monotonous infiltration of centrocyte-like cells that are CD 19(+), CD 20(+), sIgM-lambda(+), CD 3(-), CD 5(-), CD 10(-). The patient received no adjuvant chemotherapy and is alive and disease free 34 months after surgery.
authors.affiliation: Department of Internal Medicine, Shizuoka General Hospital, Japan. yagok@general-hosp.pref.shizuoka.jp
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yago
authors.forename: Hideto
authors.initials: H
authors.lastname: Shimada
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Itoh
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Ooba
authors.forename: Kazuki
authors.initials: K
authors.lastname: Itoh
authors.forename: Makoto
authors.initials: M
authors.lastname: Suzuki
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Muro
authors.forename: Shigeru
authors.initials: S
authors.lastname: Nakamura
mesh_terms: D000368:Aged; D018572:Disease-Free Survival; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D016130:Immunophenotyping; D008113:Liver Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000175:diagnosis*; D008297:Male; D009361:Neoplasm Invasiveness