Behavioral and electrophysiologic evidence of auditory processing disorder: a twin study.
We administered a battery of both behavioral and electrophysiologic measures to a pair of fraternal twin girls, one of whom exhibited symptoms consistent with an auditory processing disorder. Both twins were within normal limits on standardized tests of cognitive and language skills. Basic audiometric measures, as well as behavioral tests of simultaneous masking, backward masking, gap detection, and frequency-sweep discrimination, showed little difference between the twins. Significant differences, however, were evident on event-related potentials (ERPs) in response to both within-channel and across-channel gap detection tasks. Substantial differences were also noted for ERPs to both linguistic and nonlinguistic targets in dichotic listening paradigms. The pattern of electrophysiologic results was consistent with a deficit in the efficiency of interhemispheric transfer of auditory information. A possible reason for the greater effectiveness of electrophysiologic over behavioral measures is discussed.
Jerger
James
J
Program in Cognition and Neuroscience, The University of Texas at Dallas, USA.
Thibodeau
Linda
L
Martin
Jeffrey
J
Mehta
Jyutika
J
Tillman
Gail
G
Greenwald
Ralf
R
Britt
Lana
L
Scott
Jack
J
Overson
Gary
G
D001299:Audiometry / Q000379:methods; D001308:Auditory Perceptual Disorders / Q000150:complications* / Q000175:diagnosis; D001309:Auditory Threshold / Q000502:physiology; D002648:Child; D004007:Dichotic Listening Tests; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D010470:Perceptual Masking / Q000502:physiology; D013067:Speech Perception / Q000502:physiology; D013997:Time Factors