title: Reversal of enantioselectivity in the asymmetric rhodium- versus iridium-catalyzed hydroboration of meso substrates.
abstract: The Ir-catalyzed asymmetric hydroboration of bicyclic hydrazines with ee and chemical yields up to 64% is reported. The switch from rhodium to iridium leads systematically to opposite enantiomers in this desymmetrization reaction.
authors.affiliation: Laboratoire de Chimie Thérapeutique, UMR 8638 associée au CNRS et à l'Université René Descartes, Faculté des Sciences Pharmaceutiques et Biologiques, 4 av de l'Observatoire, 75270 Paris Cedex 06, France.
authors.forename: Alejandro Pérez
authors.initials: AP
authors.lastname: Luna
authors.forename: Martine
authors.initials: M
authors.lastname: Bonin
authors.forename: Laurent
authors.initials: L
authors.lastname: Micouin
authors.forename: Henri-Philippe
authors.initials: HP
authors.lastname: Husson