title: Rothmund-Thomson syndrome: a case report.
abstract: Rothmund-Thomson syndrome (RTS) is an extremely rare genetic disorder characterized by poikilodermatous skin changes, photosensitivity, and an increased risk of developing skin and bone malignancies. In this case report, the dental and periodontal features of RTS in a 16-year-old female patient are presented. The transmission electron microscopy performed on a gingival biopsy specimen showed structural defects of connective tissue. If the unusual ultrastructural findings of this case are confirmed as being consistent with other RTS patients, it is our opinion that this syndrome can be considered among the systemic diseases associated with early-onset periodontitis.
authors.affiliation: Department of Periodontology, Cukurova University, Bacali, Adana, Turkey. cenhaytac@yahoo.com
authors.forename: M Cenk
authors.initials: MC
authors.lastname: Haytaç
authors.forename: Haluk
authors.initials: H
authors.lastname: Oztunç
authors.forename: Ufuk O
authors.initials: UO
authors.lastname: Mete
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kaya
mesh_terms: D000293:Adolescent; D000848:Anodontia / Q000209:etiology; D003238:Connective Tissue / Q000648:ultrastructure; D003744:Dental Enamel Hypoplasia / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D017823:Furcation Defects / Q000209:etiology; D005881:Gingiva / Q000648:ultrastructure; D005884:Gingival Hemorrhage / Q000209:etiology; D006801:Humans; D007180:Incisor / Q000002:abnormalities; D008854:Microscopy, Electron; D017622:Periodontal Attachment Loss / Q000209:etiology; D010510:Periodontal Diseases / Q000209:etiology*; D010514:Periodontal Pocket / Q000209:etiology; D011038:Rothmund-Thomson Syndrome / Q000150:complications* / Q000473:pathology; D014071:Tooth Abnormalities / Q000209:etiology*; D014092:Tooth Root / Q000002:abnormalities