Photodynamic therapy with 5-aminolevulinic acid for recalcitrant familial benign pemphigus (Hailey-Hailey disease).
Familial benign pemphigus is a chronic, recurrent, autosomal dominant blistering disease that may significantly affect quality of life. Surgical methods are often needed to control flares in difficult cases. We describe the use of photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) followed by irradiation with incoherent light (ALA-PDT) in 2 patients with chronic, recalcitrant familial benign pemphigus.
Ruiz-Rodriguez
Ricardo
R
Department of Dermatology, Clínica Ruber, Madrid, Spain. rrr@jet.es
Alvarez
J G
JG
Jaén
P
P
Acevedo
A
A
Córdoba
S
S
D000622:Aminolevulinic Acid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D016506:Pemphigus, Benign Familial / Q000188:drug therapy*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D014845:Vulvar Diseases / Q000188:drug therapy
D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid