Mirror syndrome. A case report.
BACKGROUND
Water retention in a pregnant woman can mirror fetal hydropic changes. This clinical presentation has been named "mirror syndrome." Awareness of the syndrome is important due to the associated fetal and maternal risks.


METHODS
A 26-year-old woman, gravida 3, para 1011, presented at 31 weeks' gestation with significant edema and a 7-km weight gain in one week. Sonographic evaluation revealed hydramnios and fetal ascites. Maternal workup was negative for preeclampsia, diabetes, or cardiac or renal dysfunction. A workup for nonimmune hydrops was also negative. Over the next three days there was progression of maternal edema. With diagnosis of mirror syndrome, the decision for delivery was made. Both neonate and mother subsequently did well, with normalization of ascites and edema, respectively.


CONCLUSIONS
Our case, along with 19 reviewed in the literature, reiterate the features of mirror syndrome and provide an opportunity to dispel some of the misconceptions in the literature. The condition is frequently mistaken for preeclampsia, although distinguishing characteristics can be identified. Mirror syndrome is a manifestation of extremely severe fetal hydrops. When the specific cause of fetal hydrops cannot be identified and corrected, immediate delivery is necessary in order to avoid fetal death and maternal complications.
Vidaeff
Alex C
AC
Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Houston Medical School, 6431 Fannin Street, Suite 3.604, Houston, TX 77030, USA. alex.c.vidaeff@uth.tmc.edu
Pschirrer
E Rebecca
ER
Mastrobattista
Joan M
JM
Gilstrap
Larry C
LC
Ramin
Susan M
SM
D000328:Adult; D004487:Edema / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D011256:Pregnancy Outcome; D013577:Syndrome