title: Impaired stress-induced pressure natriuresis increases cardiovascularload in African American youths.
abstract: BACKGROUND
  We hypothesized that impaired stress-induced pressure natriuresis increases blood pressure (BP) load.
  
  
  METHODS
  The 118 African American youths were brought into similar levels of sodium balance. The protocol consisted of a 2-h baseline period, a 1-h stress period (competitive video games), and a 2-h recovery period.
  
  
  RESULTS
  Normal pressure natriuresis (n = 80) resulted from a resistance-mediated (r = 0.23; P <.03) increase in BP (P <.001). In contrast, impaired pressure natriuresis (n = 38), leading to an extended period of elevated BP (P <.05), resulted from a volume-mediated (r = 0.55; P <.002) increase in BP (P <.001).
  
  
  CONCLUSIONS
  Impaired stress-induced pressure natriuresis may contribute to the development of essential hypertension, particularly in African Americans.
authors.affiliation: Georgia Prevention Institute, Augusta, USA. gharshfi@mail.mcg.edu
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Harshfield
authors.forename: Martha E
authors.initials: ME
authors.lastname: Wilson
authors.forename: Coral
authors.initials: C
authors.lastname: Hanevold
authors.forename: Gaston K
authors.initials: GK
authors.lastname: Kapuku
authors.forename: Lynne
authors.initials: L
authors.lastname: Mackey
authors.forename: Delores
authors.initials: D
authors.lastname: Gillis
authors.forename: Frank A
authors.initials: FA
authors.lastname: Treiber
mesh_terms: D000293:Adolescent; D044383:Black People; D001794:Blood Pressure / Q000502:physiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000208:ethnology / Q000503:physiopathology; D008297:Male; D009318:Natriuresis / Q000502:physiology*; D012964:Sodium / Q000652:urine; D013312:Stress, Physiological / Q000208:ethnology / Q000503:physiopathology*; D014655:Vascular Resistance / Q000502:physiology; D001741:Black or African American
chemical_list: D012964:Sodium