title: Aerococcus urinae endocarditis: case report and review of the literature.
abstract: Aerococcus urinae is a rare cause of urinary tract infections, mainly in elderly men with underlying urinary tract pathologies. In addition, it has been described as a pathogen in balanitis, soft tissue infections, septicemia and endocarditis. To date ten cases of A. urinae endocarditis have been reported in the literature with a high rate of mortality (7/10) and morbidity, as two out of three survivors suffered from neurovascular complications. Here we present the case of an additional patient who was successfully treated with surgical valve replacement and antibiotic therapy consisting of ceftriaxone and netilmicin for 6 weeks. Furthermore, we review all reported cases of A. urinae endocarditis with emphasis on predisposing factors and therapeutic options.
authors.affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital, CH-8091 Zurich, Switzerland. corina.ebnoether@dim.usz.ch
authors.forename: C
authors.initials: C
authors.lastname: Ebnöther
authors.forename: M
authors.initials: M
authors.lastname: Altwegg
authors.forename: J
authors.initials: J
authors.lastname: Gottschalk
authors.forename: J D
authors.initials: JD
authors.lastname: Seebach
authors.forename: A
authors.initials: A
authors.lastname: Kronenberg
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D005500:Follow-Up Studies; D016908:Gram-Positive Bacterial Infections / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D018570:Risk Assessment; D013289:Streptococcaceae / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents