title: Black cohosh and other herbal remedies associated with acute hepatitis.
abstract: Six patients presented with clinical, biochemical and histological evidence of severe hepatitis after taking herbal remedies. One patient required urgent liver transplantation for fulminant hepatic failure after the brief use of black cohosh. Five patients took a combination of herbs and presented with jaundice, fatigue and pruritus. Healthcare providers and members of the public should be aware of the potential adverse effects of these remedies.
authors.affiliation: Princess Alexandra Hospital, Woolloongabba, QLD, Australia.
authors.forename: Peter W
authors.initials: PW
authors.lastname: Whiting
authors.forename: Andrew
authors.initials: A
authors.lastname: Clouston
authors.forename: Paul
authors.initials: P
authors.lastname: Kerlin
mesh_terms: D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D031885:Cimicifuga / Q000009:adverse effects*; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D028321:Plant Preparations / Q000009:adverse effects*; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D028321:Plant Preparations; D011241:Prednisone