The efficacy of metered-dose inhalers with a spacer device in the pediatric setting.
OBJECTIVE
To systematically review the published research and report on the efficacy of using a metered-dose inhaler with a spacer (MDI-S) device in a pediatric setting to treat acute exacerbations of asthma.


METHODS
A literature search was conducted on the CINAHL, Medline, and Cochrane databases; additional searches were made by hand from the reference lists in each study retrieved from databases and from review articles written on the same topic.


CONCLUSIONS
This critical appraisal of the research demonstrates the MDI-S is as effective as the nebulizer, faster in the delivery of medication, and cost-effective.


CONCLUSIONS
No significant difference between the MDI-S and nebulizer in delivering medication in an acute exacerbation of asthma was found in this analysis. The practitioner's choice of delivery methods should reflect the family's preference, the practice situation, and economic considerations.
Buxton
Lance J
LJ
Rural Health Clinic, Monahans, Texas, USA. lbuxton@earthlink.net
Baldwin
Joan H
JH
Berry
Judith A
JA
Mandleco
Barbara L
BL
D000208:Acute Disease; D000280:Administration, Inhalation; D000367:Age Factors; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage*; D001249:Asthma / Q000145:classification / Q000188:drug therapy* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D019317:Evidence-Based Medicine; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009330:Nebulizers and Vaporizers / Q000191:economics / Q000592:standards* / Q000600:supply & distribution; D018579:Patient Selection; D010372:Pediatrics / Q000379:methods; D012720:Severity of Illness Index
D018927:Anti-Asthmatic Agents