title: Age-related salivary polyamine increase in adolescents wearing orthodontic Ni-Ti archwires.
abstract: Until now information about the influence of puberty on gingival tissue responses to Ni-Ti alloy haven't been available. Since our previous researches have demonstrated that Ni-Ti appliances have an influence on hyperplastic gingivopathy and data has pointed out a possible hormonal influence on the susceptibility of gingival tissue to mechanical stress, we have attempted to study the relationship between fertility hormones and the periodontal response to Ni-Ti appliances. Three groups, ranging from 6 to 17 years old, were tested for salivary polyamine concentrations and for fertility hormone levels 12 months after Ni-Ti application. Results obtained from Pearson's correlation coefficient between polyamine and sexual hormone concentrations, as well as gingival and plaque indexes, suggest that the adolescent gingival tissue undergoes an hyperplastic process after long-term use of Ni-Ti appliances in relation to the puberty age-restricted peak of fertility hormones.
authors.affiliation: Department of Odontostomatology, University of Messina, Messina, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Venza
authors.forename: M
authors.initials: M
authors.lastname: Visalli
authors.forename: P
authors.initials: P
authors.lastname: Ruggeri
authors.forename: D
authors.initials: D
authors.lastname: Cicciù
authors.forename: D
authors.initials: D
authors.lastname: Teti
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005891:Gingivitis; D006801:Humans; D008297:Male; D009532:Nickel / Q000494:pharmacology*; D009967:Orthodontic Appliances; D009969:Orthodontic Wires; D011073:Polyamines / Q000032:analysis / Q000378:metabolism*; D011627:Puberty; D012463:Saliva / Q000187:drug effects* / Q000378:metabolism; D014025:Titanium / Q000494:pharmacology*
chemical_list: D011073:Polyamines; C040654:titanium nickelide; D009532:Nickel; D014025:Titanium