title: [Renal cell carcinoma in children].
abstract: Renal cell carcinoma is infrequent in children; consequently it is important to communicate its diagnosis and follow up. The behavior of this type of tumor is better characterized in adults and in this setting the treatment of choice is surgical resection. However, chemo- and radiotherapy for metastatic tumors has not been well defined. Our objective was to report the experience of a single pediatric institution in the diagnosis and treatment of renal cell carcinoma and to review the literature on this subject. We retrospectively reviewed patients diagnosed with renal cell carcinoma in the last twenty years. Only three patients were found, and we describe their clinical features and therapeutic approach. Although renal cell carcinoma is rare in children, clinical suspicion of this disease in children older than 5 years with renal masses is very important since the diagnostic and therapeutic approach differs from that for Wilms' tumor. The main prognostic factors seem to be staging and complete resection. Multicenter collaboration is required to standardize the treatment of tumors in advanced stages and to define the role of allogeneic stem cell transplantation in metastatic tumors.
authors.affiliation: Sección de Oncohematología Pediátrica, Hospital General Universitario Gregorio Marañón, Madrid, España. la.llerueb@hsvo.insalud.es
authors.forename: M E
authors.initials: ME
authors.lastname: Cela De Julián
authors.forename: A
authors.initials: A
authors.lastname: Casanova Morcillo
authors.forename: J
authors.initials: J
authors.lastname: Vázquez Estévez
authors.forename: P
authors.initials: P
authors.lastname: Galarón García
authors.forename: E
authors.initials: E
authors.lastname: Niembro De Rasche
authors.forename: M A
authors.initials: MA
authors.lastname: Cantalejo López
mesh_terms: D000293:Adolescent; D002292:Carcinoma, Renal Cell / Q000175:diagnosis*; D002648:Child; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis*; D008297:Male; D012189:Retrospective Studies