Embryonic stem cells: taming the fountain of youth.
Embryonic stem cells readily generate neurons in vitro, but steering their differentiation into specific neuronal subtypes is a major challenge. It has now been shown that mechanisms that regulate neuronal specification during development can be applied to embryonic stem cells in vitro; this may lead to new ways of generating cells for therapy.
Cassidy
Robert
R
Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-171 77 Stockholm, Sweden.
Frisén
Jonas
J
D000818:Animals; D002454:Cell Differentiation; D004622:Embryo, Mammalian; D006801:Humans; D009474:Neurons / Q000166:cytology; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology*