title: Wound healing activity and systemic effects of Vernonia scorpioides extract in guinea pig.
abstract: The ethanolic leaves extract of Vernonia scorpioides was investigated for its wound healing activity in guinea pigs. Administered once a day for 30 days, 200 mg of a hydrogel containing 50% of extract did not accelerate the closure time, but improved regeneration and organization of the new tissue.
authors.affiliation: Núcleo de Investigações Químico-Farmacêuticas, Curso de Farmácia, CCS, Universidade do Vale do Itajaí (UNIVALI). Rua: Uruguai, 458 Itajaí, Santa Caterina, 88302-202, Brazil. snleite@ccs.univali.br
authors.forename: S N
authors.initials: SN
authors.lastname: Leite
authors.forename: G
authors.initials: G
authors.lastname: Palhano
authors.forename: S
authors.initials: S
authors.lastname: Almeida
authors.forename: M W
authors.initials: MW
authors.lastname: Biavatti
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D001773:Blood Cells / Q000187:drug effects*; D004334:Drug Administration Schedule; D005260:Female; D006168:Guinea Pigs; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves; D035741:Vernonia; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D010936:Plant Extracts; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate