title: Effect of ultrasound application on fat mobilization.
abstract: The aim of this experimental trial was to study the effect of ultrasound application on the lipolysis in adipose tissue. Rats were administered to pentobarbital (Nembutal) anesthesia and their abdomens were shaved. Rat abdomen was subjected to 24 kHz-1 MHz ultrasound for 10 min to investigate frequency and power-intensity dependency for fat mobilization. Blood was taken from the tail vein to estimate plasma free fatty acids (FFA). For frequency dependency two regions around 100 kHz and 300-500 kHz were effective for fat mobilization. For power-intensity dependency, effective regions were found to be from 24 to 1090 kHz. In the effective regions on frequency and power-intensity, application of ultrasound caused increases in plasma FFA and norepinephrine concentration of extra-cellular fluid of perirenal adipose tissue. These results suggest that ultrasound application stimulates fat mobilization through a local increase in norepinephrine secretion under the conditions of effective frequency and intensity.
authors.affiliation: Miwa Science Laboratory Inc., 6-7-10 Miyazaki, Miyamae-ku, Kawasaki, 216-0033, Kanagawa, Japan
authors.forename: Hirohide
authors.initials: H
authors.lastname: Miwa
authors.forename: Masato
authors.initials: M
authors.lastname: Kino
authors.forename: Li Kun
authors.initials: LK
authors.lastname: Han
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Takaoka
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsujita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furuhata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Sugiyama
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Seno
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Morita
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kimura
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Okuda