Fusobacterium osteomyelitis in a child with sickle cell disease.
Children who have sickle cell disease are at increased risk for osteomyelitis caused by Salmonella spp. and Staphylococcus aureus. We report a case of anaerobic osteomyelitis caused by Fusobacterium nucleatum in a child with sickle cell disease. The infection did not resolve with antibiotic therapy alone, but was cured after surgical debridement and hyperbaric oxygen therapy.
Murray
Sandra J
SJ
Division of Pediatric Infectious Diseases, Department of Pediatrics Miller Children's Hospital Long Beach, CA, USA.
Lieberman
Jay M
JM
D000755:Anemia, Sickle Cell / Q000150:complications / Q000276:immunology*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002648:Child; D003131:Combined Modality Therapy; D003646:Debridement / Q000379:methods; D005500:Follow-Up Studies; D005674:Fusobacterium Infections / Q000150:complications / Q000175:diagnosis* / Q000276:immunology* / Q000628:therapy; D016967:Fusobacterium nucleatum / Q000302:isolation & purification*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D010019:Osteomyelitis / Q000150:complications / Q000276:immunology* / Q000382:microbiology* / Q000628:therapy; D018570:Risk Assessment
D000900:Anti-Bacterial Agents