Pediatric localized amyloidosis in mesopharynx.
Primary localized amyloidosis of the mesopharynx is rare. We present the case of a 12-year-old girl; as far as we are aware, our case is the third pediatric case in the English literature. Her chief complaint was a pharyngeal mass identified by the health examination at primary school. Physical examination revealed a mass in the faucial tonsil. Histologically, the lesion was composed of deposition of amyloid and chronic inflammatory cell infiltration. Immunohistochemical studies showed that the lesion was positive for amyloid P component (AP) and negative for amyloid L (AL). No treatments were applied, because she had no symptoms. During the observation period of 24 months, the mesopharyngeal mass showed no remarkable change.
Takahashi
Masahiro
M
Department of Otolaryngology, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Japan. masahir@qd5.so-net.ne.jp
Matsuda
Hideki
H
Ito
Keiko
K
Ito
Takaaki
T
Tsukuda
Mamoru
M
D000686:Amyloidosis / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010608:Pharyngeal Diseases / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D000683:Serum Amyloid P-Component / Q000378:metabolism; D014057:Tomography, X-Ray Computed
D000683:Serum Amyloid P-Component