title: Complications of deep brain stimulation surgery.
abstract: Although technological advances have reduced device-related complications, DBS surgery still carries a significant risk of transient and permanent complications. We report our experience in 86 patients and 149 DBS implants. Patients with Parkinson's disease, essential tremor and dystonia were treated. There were 8 perioperative, 8 postoperative, 9 hardware-related complications and 4 stimulation-induced side effects. Only 5 patients (6%) sustained some persistent neurological sequelae, however, 26 of the 86 patients undergoing 149 DBS implants in this series experienced some untoward event with the procedure. Although there were no fatalities or permanent severe disabilities encountered, it is important to extend the informed consent to include all potential complications.
authors.affiliation: Department of Neurosurgery, NYU School of Medicine, New York 10003, USA. aberic1@comcast.net
authors.forename: A
authors.initials: A
authors.lastname: Beric
authors.forename: P J
authors.initials: PJ
authors.lastname: Kelly
authors.forename: A
authors.initials: A
authors.lastname: Rezai
authors.forename: D
authors.initials: D
authors.lastname: Sterio
authors.forename: A
authors.initials: A
authors.lastname: Mogilner
authors.forename: M
authors.initials: M
authors.lastname: Zonenshayn
authors.forename: B
authors.initials: B
authors.lastname: Kopell
mesh_terms: D020436:Accessory Nerve Diseases / Q000209:etiology; D061227:Accessory Nerve Injuries; D000328:Adult; D000368:Aged; D001072:Apraxias / Q000209:etiology; D002543:Cerebral Hemorrhage / Q000209:etiology; D003221:Confusion / Q000209:etiology; D004401:Dysarthria / Q000209:etiology; D004421:Dystonia / Q000628:therapy; D004599:Electric Stimulation Therapy / Q000009:adverse effects*; D004567:Electrodes, Implanted / Q000009:adverse effects; D004828:Epilepsies, Partial / Q000209:etiology; D004868:Equipment Failure; D005143:Eyelids / Q000503:physiopathology; D005260:Female; D005917:Globus Pallidus; D006408:Hematoma, Subdural / Q000209:etiology; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000209:etiology; D008839:Microelectrodes; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000628:therapy; D010300:Parkinson Disease / Q000628:therapy; D013238:Stereotaxic Techniques; D013788:Thalamus; D014202:Tremor / Q000628:therapy