[Blood pressure in the extra-organ vessels and tissue blood flow in spleen in acute dose-related blood loss and perftoran application].
In experiment on dogs, using antitensiometric and histological investigations, there were shown, that before the blood loss an average blood pressure (BP) in a. femoralis (AF) is higher than in a. lienalis (AL), initial systolic BP in a. renalis (AR) is higher, than average BP in AF. After an acute dosated blood loss (DBL) occurrence of 40% of the circulating blood volume there was noted lowering of BP in AL by 6 times in comparison with that in AF. Lowering of BP in AR had leaved behind that in AF by 3 times. While the pulse BP lowering by 97.2%, in comparison with initial one, the blood stasis in AR had occurred. The perftoran application had promoted the restoration of average BP in AF up to 98.3% from the initial one and the pulse BP in AL raising--by 85%, the tissue blood flow in spleen--by 72.1%.
Izhva
V P
VP
D000208:Acute Disease; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D004285:Dogs; D005263:Femoral Artery / Q000503:physiopathology; D005269:Femur / Q000098:blood supply*; D005466:Fluorocarbons / Q000008:administration & dosage / Q000627:therapeutic use*; D006439:Hemodynamics; D007511:Ischemia / Q000503:physiopathology; D007668:Kidney / Q000098:blood supply*; D012077:Renal Artery / Q000503:physiopathology; D012771:Shock, Hemorrhagic / Q000628:therapy*; D013154:Spleen / Q000098:blood supply*; D013157:Splenic Artery / Q000503:physiopathology
D005466:Fluorocarbons; C063334:perftoran