27-Nor-triterpenoid glycosides from Mitragyna inermis.
From the bark of Mitragyna inermis, two 27-nor-triterpenoid glycosides, named inermiside I (1) and II (2), were isolated and their structures determined based on extensive 2D-NMR and MS spectral analysis as 6-deoxy-beta-D-glucopyranosyl-[3-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl]-pyrocincholate and 6-deoxy-beta-D-glucopyranosyl-pyrocincholate, respectively. In addition, the known quinovic acid (6), 3-O-[beta-D-glucopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl]-quinovoic acid (3),beta-D-glucopyranosyl-[3-O-(beta-D-glucopyranosyl)]-quinoviate (4) and cytotoxic 3-O-(beta-D-6-deoxy-glucopyranosyl)-quinovic acid (5) were also isolated.
Cheng
Zhi-Hong
ZH
Department of Complex Presection of CMM, China Pharmaceutical University, 210038, Nanjing, People's Republic of China.
Yu
Bo-Yang
BY
Yang
Xiu-Wei
XW
D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D032065:Mitragyna / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*
D006027:Glycosides; D014315:Triterpenes