Unusual presentation of carcinomatous meningitis: case report and review of typical CSF findings.
This paper describes a previously unreported clinical onset of carcinomatous meningitis with bilateral deafness. Typical changes in the cerebrospinal fluid aside from positive cytology findings are reviewed. In cases of suspected carcinomatous meningitis the clustering of increased CSF protein, lactate, decreased glucose, and a high opening pressure is suggestive of the diagnosis.
Zeller
Jörn A
JA
Department of Neurology, Christian-Albrechts-University Kiel, Germany. j.zeller@neurologie.uni-kiel.de
Zunker
Peter
P
Witt
Karsten
K
Schlueter
Erich
E
Deuschl
Günther
G
D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology*; D002277:Carcinoma / Q000134:cerebrospinal fluid* / Q000556:secondary*; D002528:Cerebellar Neoplasms / Q000378:metabolism; D002555:Cerebrospinal Fluid / Q000166:cytology / Q000378:metabolism; D003389:Cranial Nerve Diseases / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000134:cerebrospinal fluid* / Q000556:secondary*