Inflammation and immune responses in atherosclerosis.
Recent studies have highlighted the role of inflammatory mediators and the cells of the innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic plaques. Viewing this form of vascular pathology as a modified form of chronic inflammation suggests new avenues for therapeutic intervention in cardiovascular disease.
Greaves
David R
DR
Sir William Dunn School of Pathology, University of Oxford, South Parks Road, UK OX1 3RE. david.greaves@path.ox.ac.uk
Channon
Keith M
KM
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001161:Arteriosclerosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology* / Q000473:pathology; D002318:Cardiovascular Diseases / Q000209:etiology / Q000276:immunology; D002465:Cell Movement; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000276:immunology; D018836:Inflammation Mediators / Q000378:metabolism; D007962:Leukocytes / Q000276:immunology / Q000473:pathology; D018448:Models, Immunological
D000893:Anti-Inflammatory Agents; D018836:Inflammation Mediators