[The characteristics of PCNA expression in hypertrophic scars and chronic ulcers and implication of the expression].
OBJECTIVE
To investigate the characteristics of PCNA expression in hypertrophic scars and chronic ulcers and to discuss its relation to their formation.


METHODS
The expressive quantity and sites of PCNA were detected with the immunohistochemical SP method.


RESULTS
PCNA was expressed in all samples. The expressive quantity in hypertrophic scars was higher than chronic ulcers(P < 0.01). The expressive sites of all samples were in the nucleus of fibroblasts and capillary endothelial cells.


CONCLUSIONS
The expressive quantity of PCNA was more in hypertrophic scars and less n chronic ulcers. The quantitative difference of expression between hypertrophic scars and chronic ulcers may be correlated to their formation.
Sun
Tongzhu
T
304th Hospital of PLA, Beijing 100037, China.
Fu
Xiaobing
X
Gu
Xiaoman
X
Yang
Yinhui
Y
Sun
Xiaoqing
X
D000328:Adult; D017439:Cicatrix, Hypertrophic / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D018809:Proliferating Cell Nuclear Antigen / Q000096:biosynthesis*; D012883:Skin Ulcer / Q000378:metabolism* / Q000473:pathology
D018809:Proliferating Cell Nuclear Antigen