Recommendations for the prevention of osteoporosis and fragility fractures. International comparison and synthesis.
OBJECTIVE
This review included the following objectives: a) to synthesize recommendations made by public agencies in Western countries concerning screening for osteoporosis; b) to compare these recommendations and sort out the similarities and discrepancies; and c) to propose a strategy for the fight against osteoporosis and fragility fractures.


METHODS
Eleven reports published by publicly financed agencies were included in the analysis: three international, four North American and four European agencies. Transcriptions of recommendations and arguments were classified using criteria for evaluation of screening technologies.


RESULTS
Of eight reports that made a recommendation on mass screening, four made a recommendation against the use of densitometry, two remained vague with a conditionally positive recommendation, and two made no recommendation, arguing insufficient scientific evidence. Concerning screening of asymptomatic women in the perimenopause period, recommendations were uniformly opposed to the use of bone densitometry in five of nine reports, and the other four made no recommendation, arguing insufficient scientific evidence. Some of the discrepancies can be explained by the different definitions given to osteoporosis and by the confusion of terms between screening and diagnostic testing. A strategy is proposed to ensure that all women who are at risk of osteoporosis and fragility fracture have access to preventive measures. This strategy is based on the complementarity and coordination of roles between health promotion interventions and clinical interventions.


CONCLUSIONS
Prevention of osteoporosis and fragility fractures is an attainable goal. Existing resources are currently badly targeted. Compromises must be negotiated between the different stakeholders and biomedical disciplines to achieve efficiency and accessibility in the reduction of fragility fractures. A first compromise to reconcile social and scientific realities would be to use a best-evidence synthesis instead of an evidence-based medicine approach in future analyses and recommendations by public authorities. A second compromise would be to recognize the complementary roles of public health and clinical professionals toward the common objective of preventing fragility fractures.
Rossignol
Michel
M
McGill University.
Moride
Yola
Y
Perreault
Sylvie
S
Boivin
Jean-François
JF
Ste-Marie
Louis-Georges
LG
Robitaille
Yvonne
Y
Poulin de Courval
Louise
L
Fautrel
Bruno
B
D015502:Absorptiometry, Photon / Q000592:standards* / Q000706:statistics & numerical data; D000368:Aged; D015519:Bone Density / Q000502:physiology; D005060:Europe; D019317:Evidence-Based Medicine; D005260:Female; D005598:Fractures, Spontaneous / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007390:International Agencies; D008403:Mass Screening / Q000592:standards* / Q000706:statistics & numerical data; D008593:Menopause; D008875:Middle Aged; D009656:North America; D010024:Osteoporosis / Q000150:complications / Q000175:diagnosis* / Q000517:prevention & control*; D017410:Practice Guidelines as Topic / Q000592:standards*; D011635:Public Health Administration / Q000592:standards; D012307:Risk Factors; D013673:Technology Assessment, Biomedical