Hantavirus pulmonary syndrome in Uberaba, Minas Gerais, Brazil.
This report describes the epidemiological and clinical-evolutive characteristics of eight patients with hantavirus pulmonary syndrome (HPS) in Uberaba, Minas Gerais, Brazil. A positive history of contact with rodents was present in 100% of the cases. The time between the onset of symptoms and hospital care was, on average, 3.6 days. All patients showed clinical and laboratory findings suggestive of HPS. Elevated urea and creatinine levels were observed in 6 (75%) cases, PO2 was < 60 mmHg in 100% of the cases, and a chest X-ray demonstrated a bilateral interstitial-alveolar infiltrate. The diagnosis was confirmed by the detection of IgM antibodies against Sin Nombre virus by ELISA. Three patients died as a direct consequence of HPS.
Silva-Vergara
Mario León
ML
Disciplina de Doenças Infecciosas e Parasitárias, Departamento de Clínica Médica, Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG, Brasil. dip_fmtm@mednet.com.br
Costa
José Carlos
JC
Barata
Cristina Hueb
CH
Curi
Vítor Guilherme Maluf
VG
Tiveron
Carlos Giovanni
CG
Teixeira
Alan César
AC
D000328:Adult; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D005260:Female; D018804:Hantavirus Pulmonary Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D008297:Male; D008875:Middle Aged; D051381:Rats; D012377:Rodentia / Q000821:virology