Detection of acute cerebral ischaemia with Tc-99m apcitide scintigraphy.
The established indication for Tc99m apcitide scintigraphy is for detecting deep venous thrombosis. However, due to its mechanism of binding to GP IIb/IIIa receptors on activated platelets, it can be used to image acute cerebral thrombosis. I report a patient with an acute ischaemic stroke, with right leg swelling, referred for Tc99m apcitide scintigraphy to show of deep venous thrombosis. There was no abnormal uptake in the legs but there was in the left parieto-occipital region. This correlated with the clinical and CT data, indicating an acute ischaemic stroke in this area.
Tepmongkol
S
S
Nuclear Medicine Division, Department of Radiology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, Bangkok 10330, Thailand. supatporn@hotmail.com
D001921:Brain / Q000000981:diagnostic imaging*; D002545:Brain Ischemia / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010456:Peptides, Cyclic; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000378:metabolism; D011877:Radionuclide Imaging; D020521:Stroke / Q000000981:diagnostic imaging*; D020246:Venous Thrombosis / Q000000981:diagnostic imaging
D015609:Organotechnetium Compounds; D010456:Peptides, Cyclic; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; C094919:technetium Tc 99m P280