title: Neuroleptic malignant syndrome with prolonged catatonia in a dopa-responsive dystonia patient.
abstract: The authors describe a patient with dopa-responsive dystonia who developed neuroleptic malignant syndrome with prolonged catatonia following treatment with neuroleptic agents. Use of these agents probably expanded the patient's neuronal dysfunction beyond the nigrostriatal system to involve multiple dopaminergic systems. Electroconvulsive treatment alleviated the prolonged catatonia.
authors.affiliation: Department of Neurology, Kyoto University Graduate School of Medicine, Japan. ihara@kuhp.kyoto-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Ihara
authors.forename: N
authors.initials: N
authors.lastname: Kohara
authors.forename: F
authors.initials: F
authors.lastname: Urano
authors.forename: H
authors.initials: H
authors.lastname: Ichinose
authors.forename: S
authors.initials: S
authors.lastname: Takao
authors.forename: T
authors.initials: T
authors.lastname: Nishida
authors.forename: H
authors.initials: H
authors.lastname: Saiki
authors.forename: Y
authors.initials: Y
authors.lastname: Kawamoto
authors.forename: A
authors.initials: A
authors.lastname: Ikeda
authors.forename: S
authors.initials: S
authors.lastname: Takagi
authors.forename: H
authors.initials: H
authors.lastname: Shibasaki
mesh_terms: D000328:Adult; D002389:Catatonia / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D004421:Dystonia / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics; D004569:Electroencephalography / Q000187:drug effects / Q000706:statistics & numerical data; D005260:Female; D006136:GTP Cyclohydrolase / Q000235:genetics; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy
chemical_list: D007980:Levodopa; D006136:GTP Cyclohydrolase