title: Albumin-coated knitted Dacron aortic prosthses. Study of postoperative inflammatory reactions.
abstract: BACKGROUND
  The purpose of this study was to investigate the postoperative inflammatory reactions to albumin-coated Dacron grafts (ACGs), which are used in the repair of abdominal aortic aneurysm (AAA).
  
  
  METHODS
  
  
  
  METHODS
  a retrospective study with a follow-up period of 14 days.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  50 patients admitted for elective AAA repair from January 1997 to January 2000.
  
  
  METHODS
  each patient underwent AAA repair with an ACG (Bard, albumin-coated Dacron graft).
  
  
  METHODS
  the white blood cell (WBC) count, plasma C-reactive protein (CRP) concentration, and body temperature (BT) were determined. The preoperative data, the highest values of the postoperative data, and the values 2 weeks postsurgery were analyzed.
  
  
  RESULTS
  The BT, CRP, and WBC increased and peaked at the 1st week postsurgery and then decreased gradually. The BT and WBC levels returned to normal within 2 weeks. The CRP level continued to show slightly elevated values in the 2nd week, but it was not significantly different compared to the preoperative data.
  
  
  CONCLUSIONS
  The use of an albumin-impregnated prosthesis for the reconstruction of AAA is biocompatible, since no significant increases in inflammatory reactions are observed in the 2nd week postsurgery.
authors.affiliation: Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Hokkaido, Japan.
authors.forename: F A
authors.initials: FA
authors.lastname: Kudo
authors.forename: T
authors.initials: T
authors.lastname: Nishibe
authors.forename: K
authors.initials: K
authors.lastname: Miyazaki
authors.forename: J
authors.initials: J
authors.lastname: Flores
authors.forename: K
authors.initials: K
authors.lastname: Yasuda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000418:Albumins / Q000009:adverse effects*; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D020099:Coated Materials, Biocompatible / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates / Q000009:adverse effects*; D011183:Postoperative Complications; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D000418:Albumins; D020099:Coated Materials, Biocompatible; D011093:Polyethylene Terephthalates