Surgical management of pituitary adenomas.
Pituitary adenomas are a diverse group of benign neoplasms. The hormonally active tumours present with well-recognised syndromes and include acromegaly (growth hormone adenoma), Cushing's disease (corticotropin adenoma), and amenorrhea-galactorrhea (prolactin adenoma or prolactinomas). The hormonally inactive, or clinically non-secreting, adenomas generally come to clinical attention secondary to local mass effect or pituitary deficiency. With the exception of the prolactinomas, transsphenoidal surgery remains the first-line therapy for most pituitary adenomas. The current diagnosis and surgical management of pituitary adenomas is discussed.
Jane
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Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
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D000236:Adenoma / Q000175:diagnosis / Q000601:surgery*; D003480:Cushing Syndrome / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000601:surgery*