Changes in the temporomandibular joint after mandibular lengthening with different rates of distraction.
This study assessed the changes in the condyle after mandibular lengthening with 2 different rates of distraction (1 mm/day and 2 mm/day). Unilateral mandibular distraction was performed in 8 young adult goats. The animals were sacrificed 8 weeks after the completion of distraction, and the temporomandibular joint (TMJ) specimens were harvested and processed for histologic examination and histomorphometric analysis. Adaptive changes in the condyle were observed in the goats distracted at a rate of 1 mm/day, whereas degenerative alterations were found in those distracted at a rate of 2 mm/day. This study suggests that the TMJ is able to withstand the impact of distraction at a rate of 1 mm/day, but more rapid distraction may induce degeneration in the condylar cartilage.
Zou
S
S
Department of Orthodontics, Huaxi School of Stomatology, Sichuan University, Chengdu, China.
Hu
J
J
Wang
D
D
Li
J
J
Tang
Z
Z
D000818:Animals; D002146:Bony Callus / Q000473:pathology; D002356:Cartilage / Q000473:pathology; D016009:Chi-Square Distribution; D019902:Chondrocytes / Q000473:pathology; D003094:Collagen; D004396:Coloring Agents; D005456:Fluorescent Dyes; D006041:Goats; D007091:Image Processing, Computer-Assisted; D008297:Male; D008334:Mandible / Q000601:surgery*; D008335:Mandibular Condyle / Q000473:pathology; D023421:Models, Animal; D009336:Necrosis; D010006:Osteoblasts / Q000473:pathology; D019857:Osteogenesis, Distraction; D011897:Random Allocation; D013223:Statistics as Topic; D013701:Temporal Bone / Q000473:pathology; D013704:Temporomandibular Joint / Q000473:pathology*; D013997:Time Factors
D004396:Coloring Agents; D005456:Fluorescent Dyes; D003094:Collagen