title: Mycobacterium chelonae keratitis associated with soft contact lens wear.
abstract: OBJECTIVE
  To report a case of Mycobacterium chelonae keratitis associated with soft contact lens wear.
  
  
  METHODS
  A 17-year-old boy who wore frequent replacement soft contact lenses developed keratitis in the right eye. There was no history of trauma to the right eye. The patient was treated initially with topical ciprofloxacin but without improvement. On presentation, visual acuity in his right eye was 20/40. A Gram-stained scraping of the corneal infiltrate revealed beaded filamentous rods, and the organisms were acid-fast positive. The patient's right eye was treated with intensive topical amikacin, 20 mg/mL, and 10 % sulfacetamide. Eventually, Mycobacterium chelonae was cultured on Sabourard's agar, topical sulfacetamide was stopped, and amikacin was continued.
  
  
  RESULTS
  The patient's keratitis responded well to amikacin and resolved over a period of 4 weeks. Visual acuity in the right eye improved to 20/25.
  
  
  CONCLUSIONS
  Mycobacterium chelonae is a rare cause of keratitis in soft contact lens wearers. We have identified fewer than five cases of Mycobacterium chelonae keratitis associated with soft contact lenses in the literature. Prompt and accurate diagnosis of the organism using comeal scraping can lead to appropriate therapy and resolution of the keratitis.
authors.affiliation: Department of Ophthalmology, University of Minnesota, Minneapolis, USA. mmalecha@mail.eye.utmem.edu
authors.forename: Monika A
authors.initials: MA
authors.lastname: Malecha
authors.forename: Donald J
authors.initials: DJ
authors.lastname: Doughman
mesh_terms: D000293:Adolescent; D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D006801:Humans; D007634:Keratitis / Q000382:microbiology* / Q000503:physiopathology; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000209:etiology*; D016926:Mycobacterium chelonae; D014792:Visual Acuity
chemical_list: D000900:Anti-Bacterial Agents; D000583:Amikacin