Disseminated infection with encephalitozoon intestinalis in AIDS patients: report of 2 cases.
Microsporidiosis must be regarded as a late opportunistic infection when HIV is advanced. In this article we describe 2 cases of disseminated infection with Encephalitozoon intestinalis. The first case had a local intestinal infection for > 1 y before it disseminated and microsporidia were found intracellularly in sputum. In the second case, spores were initially found in conjunctival cells, sinus lavage, sputum and urine. This patient had clinical symptoms and radiological findings from the central nervous system. Signs of cerebral lymphoma developed after treatment of the opportunistic microsporidial infection.
Svedhem
Veronica
V
Department of Infectious Diseases, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden. veronica.svedhem@ks.se
Lebbad
Marianne
M
Hedkvist
Bo
B
Del Aguila
Carmen
C
Hedman
Per
P
Larsson
Ronny
R
Navajas
Raquel
R
Aust-Kettis
Agneta
A
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000503:physiopathology*; D000328:Adult; D000818:Animals; D016819:Encephalitozoon / Q000302:isolation & purification*; D016890:Encephalitozoonosis / Q000188:drug therapy / Q000503:physiopathology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged