Epidemiologic evidence on the comorbidity of depression and diabetes.
Data from population-based studies are important for the study of comorbidity. Cross-sectional research shows a consistent positive association of diabetes and depression. Prospective population-based studies are reviewed, showing that the temporal order may be from diabetes to depression, or from depression to diabetes, depending to some extent on the type of diabetes. The size of the effects is fairly consistent among the small number of studies and not trivial. Possibilities for future epidemiologic research on comorbidity are discussed.
Eaton
William W
WW
Department of Mental Hygiene, Bloomberg School of Public Health, Johns Hopkins University, 624 North Broadway, Baltimore, MD 21205, USA.
D017668:Age of Onset; D015142:Baltimore / Q000453:epidemiology; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000453:epidemiology*; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D006801:Humans; D015141:Los Angeles / Q000453:epidemiology; D011446:Prospective Studies