title: Molluscicidal and antifungal activity of Erigeron speciosus steam distillate.
abstract: The steam-distilled fraction of the aerial parts of Erigeron speciosus (Lindl) DC was tested for activity against strawberry plant pathogenic fungi Botrytis cinerea Pers ex Fr, Colletotrichum acutatum Simmonds, C fragariae Brooks, C gloeosporioides (Penz) Penz & Sacc, and the intermediate host snail Planobdella trivolvis that harbors the trematode, Bolbophorus confusus, that infests and causes severe infections in pond-raised catfish in the Mississippi Delta region of the USA. Bioautography on silica TLC plates demonstrated antifungal activity in the steam distillate. Preliminary bioassays of the steam distillate indicated the presence of phytochemicals toxic to P trivolvis. The bioactive compounds methyl 2Z, 8Z-deca-2,8-diene-4,6-diynoate and its 2E, 8E isomer were isolated by bioassay-guided fractionation and chromatographic techniques and identified by 1H NMR spectroscopy.
authors.affiliation: USDA-ARS, Natural Products Utilization Research Unit, PO Box 8048, University, MS 38677, USA. kmeepaga@olemiss.edu
authors.forename: Kumudini M
authors.initials: KM
authors.lastname: Meepagala
authors.forename: George
authors.initials: G
authors.lastname: Sturtz
authors.forename: David
authors.initials: D
authors.lastname: Wise
authors.forename: David E
authors.initials: DE
authors.lastname: Wedge
mesh_terms: D000480:Alkynes / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D020171:Botrytis / Q000187:drug effects; D002215:Captan / Q000633:toxicity; D002845:Chromatography; D020231:Colletotrichum / Q000187:drug effects; D005233:Fatty Alcohols / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D005659:Fungicides, Industrial / Q000378:metabolism / Q000633:toxicity*; D009682:Magnetic Resonance Spectroscopy; D008975:Molluscacides / Q000378:metabolism / Q000633:toxicity*; D010936:Plant Extracts / Q000378:metabolism / Q000633:toxicity*; D010986:Platyhelminths / Q000187:drug effects; D012908:Snails / Q000187:drug effects / Q000469:parasitology
chemical_list: D000480:Alkynes; D005233:Fatty Alcohols; D005659:Fungicides, Industrial; D008975:Molluscacides; D010936:Plant Extracts; C471766:methyl deca-2,8-diene-4,6-diynoate; D002215:Captan