title: [Early-onset sarcomatoid renal carcinoma. Report of a new case and comparison of the same case with another appearing at a mature age].
abstract: OBJECTIVE
  We report two new cases of this rare and aggressive tumour; one case appeared in the earliest age reported in the literature (case #2). We also review etiological, diagnostic and therapeutic features.
  
  
  RESULTS
  Despite aggressive surgery and adjuvant chemotherapy it has a very poor prognosis, with disease progression within 6 months in both cases.
  
  
  CONCLUSIONS
  Sarcomatoid renal cell carcinoma is an infrequent entity, extremely aggressive and requires radical surgery at the time of diagnosis due to its advanced stage, although results are poor. It can also appear in young people with the same aggressiveness than in adult age.
authors.affiliation: Servicio de Urología y Departamento de Anatomía Patológica, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Madrid, España. chempi@teleline.es
authors.forename: José María
authors.initials: JM
authors.lastname: García Mediero
authors.forename: José María
authors.initials: JM
authors.lastname: Alonso Dorrego
authors.forename: Carlos
authors.initials: C
authors.lastname: Nuñez Mora
authors.forename: Teresa
authors.initials: T
authors.lastname: Pastor Arquero
authors.forename: Fernando R
authors.initials: FR
authors.lastname: De Fata
authors.forename: Jesús
authors.initials: J
authors.lastname: Cisneros Ledo
authors.forename: Belén
authors.initials: B
authors.lastname: Perez Mies
authors.forename: M Luz
authors.initials: ML
authors.lastname: Picazo García
authors.forename: Y J J
authors.initials: YJ
authors.lastname: de la Peña Barthel
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D002296:Carcinosarcoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008197:Lymph Node Excision; D009392:Nephrectomy; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine