Expanding the catalytic activity of nucleophilic N-heterocyclic carbenes for transesterification reactions.
[reaction: see text] Currently, there is a renewed interest in reactions that are catalyzed by organic compounds. Typical organic catalysts for acylation or transesterification reactions are based on either nucleophilic tertiary amines or phosphines. This communication discusses the use of nucleophilic N-heterocyclic carbenes as efficient transesterification catalysts. These relatively unexplored and highly versatile organic catalysts were found to be mild, selective, and more active than traditional organic nucleophiles.
Nyce
Gregory W
GW
Center for Polymer Interfaces and Macromolecular Assemblies, IBM Almaden Research, 650 Harry Rd., San Jose, California 95120, USA.
Lamboy
Jorge A
JA
Connor
Eric F
EF
Waymouth
Robert M
RM
Hedrick
James L
JL