title: Masked o-benzoquinones in organic synthesis.
abstract: An account of the synthetic utility of masked o-benzoquinones is provided. The inter- and intramolecular Diels-Alder reactions of in situ generated masked o-benzoquinones produced cycloadducts in excellent selectivities. New synthetic methodologies have been developed for the synthesis of highly substituted ring systems including bicyclo[2.2.2]octenones, oxatricycles, triquinanes, polysubstituted cyclohexanes, and bicyclo[4.2.2]decenones with complete stereocontrol from easily accessible 2-methoxyphenols via the Diels-Alder reaction of masked o-benzoquinones. Other reactions of adducts derived from masked o-benzoquinones are also described. The efficacy of our methodology is demonstrated by several examples of the total synthesis of natural products.
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 300.
authors.forename: Chun-Chen
authors.initials: CC
authors.lastname: Liao
authors.forename: Rama Krishna
authors.initials: RK
authors.lastname: Peddinti