Advanced monitoring in the neurology intensive care unit: microdialysis.
Cerebral microdialysis is a relatively new technique for measuring the levels of brain extracellular chemicals, which to date has predominantly been used as a research tool. This review considers the technical aspects of microdialysis, the importance of the commonly measured chemicals, and the use of microdialysis to monitor patients with ischemic stroke, head injury, and subarachnoid hemorrhage. The advantages and disadvantages of microdialysis are discussed, as is its future potential.
Johnston
Andrew J
AJ
Neuro Critical Care Unit, Addenbrooke's Hospital, Cambridge, UK.
Gupta
Arun K
AK
D001923:Brain Chemistry; D001930:Brain Injuries / Q000175:diagnosis / Q000378:metabolism*; D002545:Brain Ischemia / Q000175:diagnosis; D003422:Critical Care / Q000379:methods; D005110:Extracellular Space / Q000737:chemistry; D006801:Humans; D017551:Microdialysis / Q000379:methods*; D020521:Stroke / Q000378:metabolism; D013345:Subarachnoid Hemorrhage / Q000378:metabolism*