Risk factors for indinavir-related renal colic in HIV patients: predictive value of indinavir dose/body mass index.
In a prospective study evaluating risk factors for indinavir-related renal colic in 555 HIV-infected patients receiving highly active antiretroviral therapy, followed-up fir 24 months, 23.6% developed one or more renal colic episodes, and 50 patients stopped indinavir. No correlation was observed between renal colic onset and sex, age, CD4 cell count, history, and hepatitis B or C virus co-infection, but baseline anthropometric values were significantly related to the onset of renal colic.
Meraviglia
Paola
P
2nd Department of Infectious Diseases Sacco Hospital, Milan, Italy.
Angeli
Elena
E
Del Sorbo
Francesca
F
Rombolà
Giuseppe
G
Viganò
Paolo
P
Orlando
Giovanna
G
Cordier
Laura
L
Faggion
Ivano
I
Cargnel
Antonietta
A
D000328:Adult; D015992:Body Mass Index; D003085:Colic / Q000139:chemically induced*; D004305:Dose-Response Relationship, Drug; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D019469:Indinavir / Q000008:administration & dosage / Q000009:adverse effects*; D007669:Kidney Calculi; D007674:Kidney Diseases / Q000139:chemically induced*; D008297:Male; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors
D017320:HIV Protease Inhibitors; D019469:Indinavir