title: Elastic registration of medical images through multiquadric method.
abstract: OBJECTIVE
  To improve the precision and reliability of elastic registration of the medical images and to simplify the registration process.
  
  
  METHODS
  Previous study concerning elastic registration mostly focused on manual selection of the landmarks and then use of adequate interpolating for elastic transformation. The landmarks extraction, however, was prone to error that often showed impact on the registration results, besides the difficulty and time consumption of manual identification of the landmarks. On the basis of Multiquadric method that allowed smooth adjustment of the parameters, we utilized a semi-automatic method to extract the landmarks by combining these 2 steps, and proposed a novel registration method.
  
  
  RESULTS
  Using this method for medical image elastic registration, rapid and accurate registration between standard and deformed images was achieved.
  
  
  CONCLUSIONS
  The method proposed presently is accurate, convenient and reliable.
authors.affiliation: Section of Medical Images, Department of Medical Engineering, First Military Medical University, Guangzhou 510515, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Gui-Ping
authors.initials: GP
authors.lastname: Jiang
authors.forename: Shu-Xiang
authors.initials: SX
authors.lastname: Li
authors.forename: Zhe-Xing
authors.initials: ZX
authors.lastname: Liu
authors.forename: Xiao-Mian
authors.initials: XM
authors.lastname: Xie
authors.forename: Wu-Fan
authors.initials: WF
authors.lastname: Chen
mesh_terms: D001331:Automation; D004548:Elasticity; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008432:Mathematical Computing