Glycogen synthase kinase 3/SHAGGY-like kinases in plants: an emerging family with novel functions.
Animal glycogen synthase kinase 3 (GSK-3)/SHAGGY kinases have been studied for more than 20 years, whereas plant glycogen synthase kinase 3/SHAGGY-like kinases (GSKs) have only recently entered the scene. Present evidence indicates that plant GSKs are involved in different processes, such as flower development, brassinosteroid signaling, NaCl stress and wound responses. In contrast to mammals, which contain two genes, plants have a multigene family of GSKs. Analysis of the Arabidopsis genome revealed the existence of ten GSK genes that fall into four distinct subfamilies. We discuss the functions and mechanisms of GSK action in plants and other organisms.
Jonak
Claudia
C
Institute of Microbiology and Genetics, Vienna Biocenter, University of Vienna, Dr. Bohrgasse 9, Wien, Austria. jonak@gem.univie.ac.at
Hirt
Heribert
H
D000818:Animals; D017360:Arabidopsis / Q000187:drug effects / Q000201:enzymology / Q000235:genetics; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D060406:Brassinosteroids; D002777:Cholestanols / Q000494:pharmacology; D015971:Gene Expression Regulation, Enzymologic; D038362:Glycogen Synthase Kinase 3 / Q000031:analogs & derivatives* / Q000235:genetics* / Q000378:metabolism; D007328:Insulin / Q000378:metabolism; D005810:Multigene Family / Q000235:genetics; D010802:Phylogeny; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D012965:Sodium Chloride / Q000494:pharmacology; D013260:Steroids, Heterocyclic / Q000494:pharmacology; D013314:Stress, Mechanical
D029681:Arabidopsis Proteins; D060406:Brassinosteroids; D002777:Cholestanols; D007328:Insulin; D013260:Steroids, Heterocyclic; D012965:Sodium Chloride; D011494:Protein Kinases; C085937:ATSK12 protein, Arabidopsis; C085936:ATSK11 protein, Arabidopsis; D038362:Glycogen Synthase Kinase 3; C023623:brassinolide