Synthesis of substituted cyclohexenyl-based beta-amino acids by ring-closing metathesis.
[structure: see text] A versatile ring-closing metathesis (RCM) approach has been developed for the preparation of cis and trans cyclohexenyl-based beta-amino acids that are either unsubstituted (3) or substituted (10 and 12) at the alpha-position.
Abell
Andrew D
AD
Department of Chemistry, University of Canterbury, Christchurch, New Zealand. a.abell@chem.canterbury.ac.nz
Gardiner
James
J
D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D003510:Cyclohexanes / Q000737:chemistry*; D053138:Cyclohexenes; D015394:Molecular Structure
D000596:Amino Acids; D003510:Cyclohexanes; D053138:Cyclohexenes; C052568:cyclohexene