title: Prevalence of cardiovascular abnormalities in pilots involved in fatal general aviation airplane accidents.
abstract: BACKGROUND
  Cardiovascular disease in general and coronary heart disease in particular remains the leading cause of morbidity and mortality in developed countries. Coronary artery disease is of concern in aviation because of its potential to cause sudden in-flight incapacitation. The purpose of this study was to analyze the cardiovascular abnormalities in pilots involved in fatal general aviation airplane accidents.
  
  
  METHODS
  A comprehensive review was performed of all cardiovascular abnormalities detected during autopsies conducted on pilots involved in fatal fixed-wing general aviation aircraft accidents in the U.S. from 1996-1999. Data was obtained from the database maintained at Civil Aerospace Medical Institute in Oklahoma City.
  
  
  RESULTS
  An analysis of 534 autopsy reports revealed presence of cardiovascular abnormalities in 234 pilots (prevalence rate 43.82%). Coronary artery stenosis had a prevalence rate of 37.64%. There were 41 pilots who had evidence of severe atherosclerosis of the left coronary artery. This was significantly associated with stenosis of the right coronary and circumflex arteries. There was a statistically significant relation between coronary atherosclerosis and advancing age.
  
  
  CONCLUSIONS
  Although the overall prevalence of coronary atherosclerosis is lower than previously reported, evidence of severe atherosclerosis was found in a relatively high percentage of pilots and may be a cause for concern. The findings have implications for aircrew health education and primary prevention programs. There is also a need for more standardized data collection.
authors.affiliation: University of Illinois at Urbana-Champaign, Aviation Human Factors Division, Savoy 61874, USA.
authors.forename: Narinder
authors.initials: N
authors.lastname: Taneja
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Wiegmann
mesh_terms: D000060:Accidents, Aviation / Q000401:mortality*; D000328:Adult; D000337:Aerospace Medicine; D003324:Coronary Artery Disease / Q000453:epidemiology; D003327:Coronary Disease / Q000453:epidemiology*; D023921:Coronary Stenosis / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D016272:Occupational Health; D014481:United States / Q000453:epidemiology