Population data of five genetic markers in the Turkish population: comparison with four American population groups.
In this study, the phenotype and allele frequencies of five enzyme systems were determined in a total of 611 unrelated Turkish individuals and analyzed by using the exact and the chi 2 test. The following five red cell enzymes were identified by cellulose acetate electrophoresis: phosphoglucomutase (PGM), adenosine deaminase (ADA), phosphoglucose isomerase (PGI), adenylate kinase (AK), and 6-phosphogluconate dehydrogenase (6-PGD). The ADA, PGM and AK enzymes were found to be polymorphic in the Turkish population. The results of the statistical analysis showed, that the phenotype frequencies of the five enzyme under study are in Hardy-Weinberg equilibrium. Statistical analysis was performed in order to examine whether there are significant differences in the phenotype frequencies between the Turkish population and four American population groups. This analysis showed, that there are some statistically significant differences between the Turkish and the other groups. Moreover, the observed phenotype and allele frequencies were compared with those obtained in other population groups of Turkey.
Kurtuluş-Ulküer
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Kirşehir Education Faculty, Biology Department, Gazi University, Kirşehir, Turkey. unerulkuer@hotmail.com
Ulküer
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Kesici
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Menevşe
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D000243:Adenosine Deaminase / Q000235:genetics; D000263:Adenylate Kinase / Q000235:genetics; D003431:Cross-Cultural Comparison; D004912:Erythrocytes / Q000201:enzymology*; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics*; D005828:Genetics, Population; D005956:Glucose-6-Phosphate Isomerase / Q000235:genetics; D006801:Humans; D010641:Phenotype; D010733:Phosphoglucomutase / Q000235:genetics; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics; D014421:Turkey; D014481:United States
D005819:Genetic Markers; D010734:Phosphogluconate Dehydrogenase; D000263:Adenylate Kinase; D000243:Adenosine Deaminase; D005956:Glucose-6-Phosphate Isomerase; D010733:Phosphoglucomutase