title: In vitro studies of the influence polyester materials with a different degree of surface wettability have on blood haematological parameters and coagulation and fibrinolysis system parameters.
abstract: The paper presents the studies of the influence polyester knitings with a different degree of surface wettability have on the coagulation system, fibrinolytic system and blood haematological parameters in in vitro studies. The studies of Human whole blood were performed for 5, 15, 30, 60, 90, 180 and 240 min. In view of the obtained results in has been reported that a hydrophobic surface knitting does not cause important quantitative changes in any of the selected parametes of the coagulation system and fibrinolysis system. A hydrophilic surface polyester knit causes important lengthening of aPTT value and reduced factor XII, IX and VIII activity. A hydrophilic surface polyester knitting causes a bigger decrease in leukocytes and blood platelets and a bigger increase in beta thromboglobulin in relation to the hydrophobic surface knitting. Neither hydrophobic surface knit nor hydrophilic surface knitting cause changes in the erythrocyte system.
authors.affiliation: Department of Experimental Surgery and Biomaterials Research, Clinic Traumatology, Wrocław Medical University.
authors.forename: Danuta
authors.initials: D
authors.lastname: Paluch
authors.forename: Maria
authors.initials: M
authors.lastname: Szymonowicz
authors.forename: Stanisław
authors.initials: S
authors.lastname: Pielka
authors.forename: Roman
authors.initials: R
authors.lastname: Rutowski
mesh_terms: D001777:Blood Coagulation / Q000502:physiology*; D001792:Blood Platelets / Q000648:ultrastructure; D004912:Erythrocytes / Q000648:ultrastructure; D005342:Fibrinolysis; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D066298:In Vitro Techniques; D007958:Leukocyte Count; D007962:Leukocytes / Q000648:ultrastructure; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010976:Platelet Count; D011091:Polyesters / Q000737:chemistry; D017155:Wettability; D001620:beta-Thromboglobulin / Q000032:analysis
chemical_list: D011091:Polyesters; D001620:beta-Thromboglobulin