title: Workplace monitoring for volatile organic compounds using thermal desorption-gas chromatography-mass spectrometry.
abstract: The interest in the identification of volatile organic compounds in the workplace has been a major focus of many National Institute for Occupational Safety and Health (NIOSH) field studies. A primary technique for sampling and analysis of these compounds is summarized by NIOSH Manual of Analytical Methods (NMAM) 2549. This is a screening method that uses a multi-bed sorbent to trap a wide variety of compounds and compound classes. Thermal desorption techniques are used as a first attempt to characterize potential contaminants in a workplace and to determine what future sampling and analyses must be performed. Field examples are provided to show the versatility of thermal desorption methods and techniques. Due to their sensitivity, thermal desorption tube methods are sometimes required in order to measure the workplace concentrations of unusual compounds. In other situations, the exposures are too high or varied to make thermal desorption tubes practical. In these cases, the identification of contaminants with thermal desorption tubes leads to new method developments for the quantification of specific compounds using more conventional solid sorbent-solvent desorption based methods.
authors.affiliation: Chemical Exposure and Monitoring Branch, Division of Applied Research and Technology, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH 45226, USA.
authors.forename: Ardith A
authors.initials: AA
authors.lastname: Grote
authors.forename: Eugene R
authors.initials: ER
authors.lastname: Kennedy
mesh_terms: D016902:Air Pollution, Indoor / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D009314:National Institute for Occupational Safety and Health, U.S.; D012016:Reference Values; D012680:Sensitivity and Specificity; D014481:United States; D014835:Volatilization; D017132:Workplace