New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. II. Physicochemical properties and structure elucidation.
Three new natural dithiopyrrolone antibiotics, 3-methyl-2-butenoylpyrrothine (1), tigloylpyrrothine (2), and n-butyropyrrothine (3) were isolated along with the known isobutyropyrrothine (4) and thiolutin (5) from the fermentation broth of Saccharothrix sp. SA 233. The structures of the novel compounds were established on the basis on their spectral data.
Lamari
Lynda
L
Laboratoire de Recherche sur les Produits Bioactifs et al Valorisation de la Biomasse, Ecole Normale Supérieure de Kouba, Alger, Algérie.
Zitouni
Abdelghani
A
Dob
Tahar
T
Sabaou
Nasserdine
N
Lebrihi
Ahmed
A
Germain
Pierre
P
Seguin
Elisabeth
E
Tillequin
François
F
D000192:Actinomycetales / Q000254:growth & development / Q000378:metabolism* / Q000502:physiology; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D009682:Magnetic Resonance Spectroscopy; D011760:Pyrrolidinones / Q000737:chemistry*; D019265:Spectroscopy, Near-Infrared
C467212:3-methyl-2-butenoylpyrrothine; D000900:Anti-Bacterial Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D011760:Pyrrolidinones; C467215:iso-butyropyrrothine; C467213:n-butyropyrrothine; C467214:tigloylpyrrothine; C006361:acetopyrrothine