title: Intrathecal treatment for spasticity.
abstract: Although initially to be treated by oral spasmolytics, established spasticity is being increasingly recognised as needing direct pharmacotherapy to the spinal cord by the intrathecal route using drug delivery systems. Although the spasticity is mainly of spinal origin due to trauma or multiple sclerosis (M.S.), it can emanate from the brain as in cerebral palsy in children and require the same direct treatment. Drug delivery systems are now proven to be safe, clinically reliable, and cost effective and should be considered earlier in the disease process.
authors.affiliation: Pain Relief Foundation, University of Liverpool, UK.
authors.forename: J
authors.initials: J
authors.lastname: Miles
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D007278:Injections, Spinal; D009128:Muscle Spasticity / Q000188:drug therapy*; D010276:Parasympatholytics / Q000008:administration & dosage*
chemical_list: D010276:Parasympatholytics