title: The potential of preoperative beta-hCG and progesterone levels to predict failure of laparoscopic linear salpingostomy in ectopic pregnancies.
abstract: OBJECTIVE
  To estimate the association between preoperative beta-human chorionic gonadotropin (hCG) and progesterone levels, and success of linear salpingostomy in treatment of tubal pregnancy.
  
  
  METHODS
  Retrospective case control study (Canadian Task Force classification II-1).
  
  
  METHODS
  Women's general hospital.
  
  
  METHODS
  Three hundred five women undergoing laparoscopic linear salpingostomy for ectopic pregnancy.
  
  
  METHODS
  Examination of risk factors for surgical failure of salpingostomy by analyzing corresponding receiver operating curves.
  
  
  RESULTS
  In 305 women, intervention was successful in 272 and failed in 33, as assessed by either postoperative hemorrhage (16) or rising beta-hCG values (14); 3 women had both. Of 295 patients in whom beta-hCG was evaluated preoperatively, 149 (50.5%) had values of 1000 mU/ml. or less; 75% had progesterone levels of 10 ng/ml or below. No association was found between preoperative beta-hCG and progesterone levels and the success of linear salpingostomy.
  
  
  CONCLUSIONS
  Preoperative beta-hCG and progesterone levels are of no significance with regard to success of linear salpingostomy for treatment of tubal pregnancy.
authors.affiliation: Department of Gynecology and Obstetrics, Women's General Hospital, Lederergasse 47, A-4020 Linz, Austria.
authors.forename: Gernot
authors.initials: G
authors.lastname: Tews
authors.forename: Thomas
authors.initials: T
authors.lastname: Ebner
authors.forename: Cemil
authors.initials: C
authors.lastname: Yaman
authors.forename: Werner
authors.initials: W
authors.lastname: Pölz
authors.forename: Michael
authors.initials: M
authors.lastname: Sommergruber
authors.forename: Johannes
authors.initials: J
authors.lastname: Hartl
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood / Q000378:metabolism*; D016001:Confidence Intervals; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood / Q000175:diagnosis* / Q000601:surgery*; D011300:Preoperative Care; D011336:Probability; D011374:Progesterone / Q000097:blood / Q000378:metabolism*; D012372:ROC Curve; D012189:Retrospective Studies; D012489:Salpingostomy / Q000009:adverse effects / Q000379:methods*; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D018997:Chorionic Gonadotropin, beta Subunit, Human; D011374:Progesterone