Topical tacrolimus for repigmentation of vitiligo.
We describe 6 patients with generalized vitiligo who responded to treatment with tacrolimus ointment. Moderate to excellent repigmentation was achieved in 5 patients. Although the number of cases in this noncontrolled, nonblinded series is small, tacrolimus ointment may be an efficacious and safe treatment option for vitiligo.
Grimes
Pearl E
PE
Vitiligo and Pigmentation Institute of Southern California, Los Angeles, CA, USA. pegrimesmd@earthlink.net
Soriano
Teresa
T
Dytoc
Marlene T
MT
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D009824:Ointments; D012880:Skin Pigmentation / Q000187:drug effects*; D016559:Tacrolimus / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D014820:Vitiligo / Q000188:drug therapy*
D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus