Aspergillin PZ, a novel isoindole-alkaloid from Aspergillus awamori.
Aspergillin PZ was obtained from the fermentation of Aspergillus awamori (Nakazawa) by activity-guided fractionation and purification. Its structure was elucidated on the basis of spectral data, especially by 2D NMR, and finally confirmed by an X-ray analysis. It could induce conidia of P. oryzae to deform moderately.
Zhang
Yi
Y
College of Traditional Chinese Medicines, Shenyang Pharmaceutical University.
Wang
Tao
T
Pei
Yuehu
Y
Hua
Huiming
H
Feng
Baomin
B
D000470:Alkaloids / Q000096:biosynthesis / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology; D001203:Ascomycota / Q000187:drug effects / Q000254:growth & development; D001230:Aspergillus / Q000254:growth & development / Q000378:metabolism*; D005912:Gliotoxin / Q000096:biosynthesis / Q000737:chemistry / Q000494:pharmacology; D026121:Indole Alkaloids / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D007211:Indoles / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012988:Soil Microbiology; D014965:X-Rays
D000470:Alkaloids; D000935:Antifungal Agents; D026121:Indole Alkaloids; D007211:Indoles; C467211:aspergillin PZ; D005912:Gliotoxin