title: Mumps: immune status of adults and epidemiology as a necessary background for choice of vaccination strategy in Jordan.
abstract: The prevalence of antibodies against mumps in 333 students at Jordan University was assessed using the ELISA technique. Most of the students (93.7%) were seropositive for mumps. About 50% of unvaccinated students and students vaccinated using the optional single-dose MMR vaccine had mumps. The incidence rate of mumps in different age groups and sexes, the geographic distribution and the seasonality of mumps infection prior to the adoption of compulsory MMR vaccination were investigated during the period from 1988 to 2000. Mumps occurred in all age groups in both sexes and the incidence rate was higher in children aged 5-14 years than in adults. There was a higher frequency in winter and spring with epidemic peaks in 1988, 1993 and 2000. Southern Jordan had the highest incidence rate due to low vaccination coverage by the private clinics. The data support the introduction of compulsory MMR vaccination in Jordan for all susceptible individuals. Evaluation of the effectiveness of the compulsory single-dose vaccine and, based on the outcome, a second dose of this vaccine is also recommended in order to achieve and maintain a high level of immunization.
authors.affiliation: Department of Biological Sciences, Faculty of Science, University of Jordan, Amman, Jordan. bsalwa@sci.ju.edu.jo
authors.forename: Naji
authors.initials: N
authors.lastname: Batayneh
authors.forename: Salwa
authors.initials: S
authors.lastname: Bdour
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007597:Jordan / Q000453:epidemiology; D008297:Male; D032541:Mass Vaccination; D022542:Measles-Mumps-Rubella Vaccine / Q000276:immunology / Q000592:standards; D008875:Middle Aged; D009107:Mumps / Q000453:epidemiology* / Q000276:immunology* / Q000821:virology; D009109:Mumps virus / Q000276:immunology*; D015995:Prevalence; D012621:Seasons; D016036:Seroepidemiologic Studies; D012737:Sex Factors
chemical_list: D000914:Antibodies, Viral; D022542:Measles-Mumps-Rubella Vaccine