title: A novel three-component reaction for the diastereoselective synthesis of 2H-pyrimido[2,1-a]isoquinolines via 1,4-dipolar cycloaddition.
abstract: [reaction: see text] The 1,4-dipole derived from isoquinoline and DMAD has been shown to react readily with N-tosylimines resulting in the diastereoselective synthesis of 2H-pyrimido[2,1-a]isoquinoline derivatives.
authors.affiliation: Organic Chemistry Division, Regional Research Laboratory, CSIR, Trivandrum 695 019, India. gvn@csrrltrd.ren.nic.in
authors.forename: Vijay
authors.initials: V
authors.lastname: Nair
authors.forename: A R
authors.initials: AR
authors.lastname: Sreekanth
authors.forename: N
authors.initials: N
authors.lastname: Abhilash
authors.forename: Mohan M
authors.initials: MM
authors.lastname: Bhadbhade
authors.forename: Rajesh C
authors.initials: RC
authors.lastname: Gonnade