title: Successful surgical treatment of peritoneal dissemination of hepatocellular carcinoma.
abstract: Hepatocellular carcinoma rarely disseminates intraperitoneally. When it does, it usually is considered a terminal event. The successful treatment of complications of peritoneal metastases by surgical resection in a patient with hepatocellular carcinoma is reported. A 63-year-old man with hepatocellular carcinoma in the anterior segment underwent transarterial and portal embolization followed by extended radical hepatectomy. Five years and 8 months later, he presented with an ileus that was secondary to multiple peritoneal metastases that were resected to the extent possible. Eight months later, the patient presented with a second episode of ileus and underwent another operation that included bowel resection. However, pelvic tumors that were unresectable also were present. The patient survived for another 9 months before dying with peritoneal carcinomatosis. Although surgical treatment of peritoneal dissemination of hepatocellular carcinoma is not curative, surgery may improve survival and provide a good quality of life in selected cases.
authors.affiliation: First Department of Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yoshida
authors.forename: Masahiko
authors.initials: M
authors.lastname: Onda
authors.forename: Takashi
authors.initials: T
authors.lastname: Tajiri
authors.forename: Koho
authors.initials: K
authors.lastname: Akimaru
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takasaki
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Mamada
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Taniai
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Youichi
authors.initials: Y
authors.lastname: Kawano
authors.forename: Tsubasa
authors.initials: T
authors.lastname: Takahashi
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D003106:Colon / Q000473:pathology / Q000601:surgery; D004621:Embolization, Therapeutic; D017809:Fatal Outcome; D006498:Hepatectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009366:Neoplasm Seeding; D010534:Peritoneal Neoplasms / Q000473:pathology / Q000601:surgery*