The potential of preoperative beta-hCG and progesterone levels to predict failure of laparoscopic linear salpingostomy in ectopic pregnancies.
OBJECTIVE
To estimate the association between preoperative beta-human chorionic gonadotropin (hCG) and progesterone levels, and success of linear salpingostomy in treatment of tubal pregnancy.


METHODS
Retrospective case control study (Canadian Task Force classification II-1).


METHODS
Women's general hospital.


METHODS
Three hundred five women undergoing laparoscopic linear salpingostomy for ectopic pregnancy.


METHODS
Examination of risk factors for surgical failure of salpingostomy by analyzing corresponding receiver operating curves.


RESULTS
In 305 women, intervention was successful in 272 and failed in 33, as assessed by either postoperative hemorrhage (16) or rising beta-hCG values (14); 3 women had both. Of 295 patients in whom beta-hCG was evaluated preoperatively, 149 (50.5%) had values of 1000 mU/ml. or less; 75% had progesterone levels of 10 ng/ml or below. No association was found between preoperative beta-hCG and progesterone levels and the success of linear salpingostomy.


CONCLUSIONS
Preoperative beta-hCG and progesterone levels are of no significance with regard to success of linear salpingostomy for treatment of tubal pregnancy.
Tews
Gernot
G
Department of Gynecology and Obstetrics, Women's General Hospital, Lederergasse 47, A-4020 Linz, Austria.
Ebner
Thomas
T
Yaman
Cemil
C
Pölz
Werner
W
Sommergruber
Michael
M
Hartl
Johannes
J
D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood / Q000378:metabolism*; D016001:Confidence Intervals; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood / Q000175:diagnosis* / Q000601:surgery*; D011300:Preoperative Care; D011336:Probability; D011374:Progesterone / Q000097:blood / Q000378:metabolism*; D012372:ROC Curve; D012189:Retrospective Studies; D012489:Salpingostomy / Q000009:adverse effects / Q000379:methods*; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
D015415:Biomarkers; D018997:Chorionic Gonadotropin, beta Subunit, Human; D011374:Progesterone