Mathematics-assisted mapping in analysis of medical disease.
Genetic mapping in analysis of medical disease is performed under several assumptions and (experimental) conditions, which are made about the data in general and the disease in particular. Here we discuss these conditions, what they mean, and what kind of deleterious effects they might have on the analysis. We also illustrate how to proceed and what kind of possibilities the statistical analysis may provide to medical scientists.
Sillanpää
Mikko J
MJ
Rolf Nevanlinna Institute, University of Helsinki, Finland. mjs@rolf.helsinki.fi
D002874:Chromosome Mapping; D003627:Data Interpretation, Statistical; D018740:Genetic Heterogeneity; D005826:Genetics, Medical / Q000379:methods*; D005828:Genetics, Population; D023421:Models, Animal; D010641:Phenotype