[A rare clinical case of Sipple disease].
Multiple endocrine neoplasia (MEN) unites a group of syndromes caused by tumors or hyperplasia of several endocrine glands. We examined and treated patients (father and daughter) with Sipple disease, or type II MEN; the diagnosis was confirmed at Institute of Clinical Endocrinology (Moscow). The aim of our report was to supplement the clinical picture of the disease. Clinical examinations showed thickened corneal nerves, the dry eye syndrome, and abnormal refraction.
Afendulova
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D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000601:surgery; D000315:Adrenalectomy; D000328:Adult; D001251:Astigmatism / Q000175:diagnosis*; D018276:Carcinoma, Medullary / Q000150:complications / Q000601:surgery; D003315:Cornea / Q000294:innervation*; D015352:Dry Eye Syndromes / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D018813:Multiple Endocrine Neoplasia Type 2a / Q000175:diagnosis* / Q000235:genetics; D010673:Pheochromocytoma / Q000150:complications / Q000601:surgery; D013964:Thyroid Neoplasms / Q000150:complications / Q000601:surgery; D013965:Thyroidectomy