[DNA polymorphism in population genetics].
In the review, the literature evidence on DNA polymorphism obtained in the last 10-15 years using various molecular-genetic methods is summarized. All main types of DNA variation are considered but attention is focused on those extensively used in population genetics. The areas of using DNA markers are outlined and the limitations of their potential in analyzing genetic processes in populations are discussed. Particular emphasis is placed on the relationship between the earlier developed biochemical genetics based on protein polymorphism analysis and modern molecular population genetics based on DNA polymorphism. The possible role of selection in maintaining DNA variation is considered.
Altukhov
Iu P
IuP
Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991 Russia. yualt@vigg.ru
Salmenkova
E A
EA
D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics; D020224:Expressed Sequence Tags; D005821:Genetic Techniques; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D018598:Minisatellite Repeats; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D019105:Random Amplified Polymorphic DNA Technique; D015183:Restriction Mapping; D016324:Sequence Tagged Sites; D020086:Short Interspersed Nucleotide Elements; D014998:Y Chromosome
D004272:DNA, Mitochondrial