Two Dictyostelium ribosomal proteins act as RNases for specific classes of mRNAs.
Phosphorylation of ribosomal protein S6 leads to the stabilization of pre-spore specific mRNAs during development of Dictyostelium discoideum. The purification of S6 kinase has allowed the identification of protein S11 as the mRNase specific for pre-spore mRNAs. Methylation of ribosomal protein S31 leads to the destabilization of ribosomal protein mRNAs. The purification of S31 methyltransferase has allowed the identification of protein S29 as the mRNAse specific for ribosomal protein mRNAs.
Mangiarotti
Giorgio
G
Department of Biological Sciences, University of Windsor, 401 Sunset Avenue, Ontario, 9NB 3P4, Canada. vale.mangiarotti@katamail.com
D000818:Animals; D004023:Dictyostelium / Q000201:enzymology*; D008745:Methylation; D012333:RNA, Messenger / Q000378:metabolism; D012260:Ribonucleases / Q000378:metabolism*; D019893:Ribosomal Protein S6 Kinases / Q000378:metabolism; D012269:Ribosomal Proteins / Q000378:metabolism*
D012333:RNA, Messenger; D012269:Ribosomal Proteins; C045454:ribosomal protein S11; C079855:ribosomal protein S29; C059034:ribosomal protein S31, Dictyostelium discoideum; D019893:Ribosomal Protein S6 Kinases; D012260:Ribonucleases