title: Transcription activation: unveiling the essential nature of TFIID.
abstract: The TAF subunits of TFIID mediate activation of subsets of the eukaryotic genome. Recent results demonstrate that TFIID is recruited to promoters in an activator-specific manner involving functional interaction between upstream regulatory elements and the core promoter, thereby coordinating the expression of distinct sets of genes.
authors.affiliation: Department of Biochemistry, Division of Nucleic Acids Enzymology, Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.
authors.forename: Bo-Shiun
authors.initials: BS
authors.lastname: Chen
authors.forename: Michael
authors.initials: M
authors.lastname: Hampsey
mesh_terms: D000818:Animals; D006801:Humans; D046911:Macromolecular Substances; D008954:Models, Biological; D021122:Protein Subunits; D035381:TATA-Binding Protein Associated Factors / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D035362:Transcription Factor TFIID / Q000737:chemistry / Q000235:genetics* / Q000502:physiology*; D015533:Transcriptional Activation
chemical_list: D046911:Macromolecular Substances; D021122:Protein Subunits; D035381:TATA-Binding Protein Associated Factors; D035362:Transcription Factor TFIID