title: Splenic actinomycotic abscess in a patient with acute myeloid leukemia.
abstract: Actinomycosis is a gram-positive anaerobic bacterium. Actinomyces organisms are important constituents of the normal flora of mucous membranes and are considered opportunistic pathogens. The three major clinical presentations of actinomycosis include the cervicofacial, thoracic, and abdominopelvic regions. Actinomycosis infection in patients with febrile neutropenia is uncommon and actinomycosis splenic involvement in acute leukemia patients is very rare. We describe a man with acute myeloid leukemia and splenic actinomycotic abscess that developed after chemotherapy following prolonged neutropenia.
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital, No. 7, Chung-Shan South Road, Taipei 100, Taiwan.
authors.forename: C-Y
authors.initials: CY
authors.lastname: Chen
authors.forename: Y-C
authors.initials: YC
authors.lastname: Chen
authors.forename: J-L
authors.initials: JL
authors.lastname: Tang
authors.forename: W-C
authors.initials: WC
authors.lastname: Lin
authors.forename: I-J
authors.initials: IJ
authors.lastname: Su
authors.forename: H-F
authors.initials: HF
authors.lastname: Tien
mesh_terms: D000196:Actinomycosis / Q000139:chemically induced / Q000175:diagnosis* / Q000382:microbiology; D000208:Acute Disease; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000633:toxicity; D003937:Diagnosis, Differential; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis; D009503:Neutropenia / Q000150:complications; D009894:Opportunistic Infections / Q000175:diagnosis / Q000382:microbiology; D013158:Splenic Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000382:microbiology*