title: [Ulcerous gastrointestinal bleedings].
abstract: On the basis of the study of 2388 patients with chronic gastric and duodenal ulcers complicated by acute bleeding, the most disputable organizational and tactical issues of ulcer bleeding (UB) treatment are discussed. It is reasonable to divide surgery for UB into urgent, delayed and elective. Indications for different surgeries in UB and basic surgical principles are discussed. Severe blood loss is the main factor of general lethality. Combined conservative therapy must provide correction of posthemorrhagic tissue hypoxia, functional disorders, hemostatic disturbances and immunosuppression. Artificial transmitters of oxygen and infusion of antihypoxants are promising in management of UB. Antisecretory drugs are a necessary component of conservative treatment in UB. Therapeutic endoscopy is important in the treatment of acute UB, but it is not alternative to surgical hemostasis. It may be regarded as a method of temporary hemostasis before delayed for more than 2 hours operation or as a method of final hemostasis in combined conservative treatment, first of all in patients of "surgical risk" group.
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Stoĭko
authors.forename: S F
authors.initials: SF
authors.lastname: Bagnenko
authors.forename: A A
authors.initials: AA
authors.lastname: Kurygin
authors.forename: V G
authors.initials: VG
authors.lastname: Verbitskiĭ
authors.forename: O N
authors.initials: ON
authors.lastname: Skriabin
mesh_terms: D001774:Blood Chemical Analysis; D004638:Emergency Treatment / Q000379:methods; D006801:Humans; D010438:Peptic Ulcer Hemorrhage / Q000401:mortality / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality; D013997:Time Factors