title: Have we solved the problem of late thrombosis?
abstract: Late thrombosis (angiographic total occlusion associated with an acute coronary syndrome) is potentially a life-threatening complication after intracoronary radiation therapy. This review is intended to explore the pre-clinical and clinical evidence for late thrombosis, discuss the etiology, and provide guidelines for future management. Although we have gained a greater understanding of this complex entity, further research is required to curtail late thrombosis rates.
authors.affiliation: Cardiovascular Research Institute, Washington Hospital Center, Washington DC, USA.
authors.forename: A E
authors.initials: AE
authors.lastname: Ajani
authors.forename: E
authors.initials: E
authors.lastname: Cheneau
authors.forename: L
authors.initials: L
authors.lastname: Leborgne
authors.forename: R
authors.initials: R
authors.lastname: Wolfram
authors.forename: R
authors.initials: R
authors.lastname: Waksman
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D000818:Animals; D001918:Brachytherapy; D002986:Clinical Trials as Topic; D015331:Cohort Studies; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000628:therapy*; D023903:Coronary Restenosis / Q000517:prevention & control*; D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage; D015607:Stents; D013552:Swine; D013927:Thrombosis / Q000517:prevention & control*; D013997:Time Factors