[Functional connection between the marginal division and hippocampus in rats].
OBJECTIVE
To investigate the functional connection between the marginal division of the striatum and hippocampus, a brain region that play a vital role in learning and memory.


METHODS
Morphological localization of functional activity of the nervous system was employed. Kainic acid (0.01%) was stereotaxically injected into the hippocampus as a chemical stimulus, and immunohistochemistry method was used to show the expression of c-Fos in rat brain.


RESULTS
c-Fos was intensely expressed in the hippocampus, amygdaloid nucleus, the bed nucleus of the stria terminals and cerebral cortex; in the striatum, a stretch in the marginal division where c-Fos-positive nuclei congregated was observed, while c-Fos expression was scarcely detectable in the caudate putamen and globus pallidus.


CONCLUSIONS
Functional connection exists between the marginal division and hippocampus in rats.
Ning
Qun
Q
Institute for Neuroscience, First Military Medical University, Guangzhou 510282, China.
Shu
Si-Yun
SY
Bao
Xin-Min
XM
D000818:Animals; D006624:Hippocampus / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D007150:Immunohistochemistry; D007608:Kainic Acid / Q000494:pharmacology; D007858:Learning / Q000502:physiology; D008297:Male; D008568:Memory / Q000502:physiology; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley
D016760:Proto-Oncogene Proteins c-fos; D007608:Kainic Acid