title: A new method for synthesis of 7-deoxytaxane analogues by hydrogenation of delta(6,7)-taxane derivatives.
abstract: A new method for the synthesis of 7-deoxytaxane analogues has been established through hydrogenation of Delta(6,7)-taxane derivatives. Among several catalysts examined, Pd-C was found to be a most effective catalyst for the preparation of target compound.
authors.affiliation: Medicinal Chemistry Research Laboratory, Daiichi Pharmaceutical Co., Ltd., Tokyo R&D Center, Japan.
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Takeda
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Yoshino
authors.forename: Kouichi
authors.initials: K
authors.lastname: Uoto
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Terasawa
authors.forename: Tsunehiko
authors.initials: T
authors.lastname: Soga
mesh_terms: D001952:Bridged-Ring Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006865:Hydrogenation; D043823:Taxoids
chemical_list: D001952:Bridged-Ring Compounds; D043823:Taxoids; C080625:taxane