Sequential emergence of antibiotic resistance in enterococcal bloodstream isolates over 25 years.
We determined the antibiotic susceptibilities of 1,785 enterococcal bloodstream isolates collected over 25 years. Antibiotic resistance emerged at a greater rate in Enterococcus faecium than in other enterococcal species, and E. faecium isolates became proportionally more common over time. Our findings confirm the pattern of emerging antibiotic resistance among enterococci and highlight the increasing importance of E. faecium as a cause of bloodstream infection.
Murdoch
David R
DR
Clinical Microbiology Laboratories, Duke University Medical Center, Durham, North Carolina 27710, USA. david.murdoch@cdhb.govt.nz
Mirrett
Stanley
S
Harrell
Lizzie J
LJ
Monahan
Janet S
JS
Reller
L Barth
LB
D003120:Colorado / Q000453:epidemiology; D024881:Drug Resistance, Bacterial; D016983:Enterococcus / Q000187:drug effects*; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D009657:North Carolina / Q000453:epidemiology; D011159:Population Surveillance; D013997:Time Factors; D014481:United States / Q000453:epidemiology