title: [The evaluation of the second-look operation of patients with ovarian carcinoma and tubal carcinoma by means of a retrospective comparison study].
abstract: BACKGROUND
  This investigation is a retrospective analysis to evaluate the influence of second-look surgery on the relapse-free and overall survival of patients with ovarian and tubal carcinomas.
  
  
  METHODS
  For 208 patients with and without second-look operation out of 469 of the total collective, a matched analysis and a Cox regression model were established in the framework of a multivariate analysis.
  
  
  RESULTS
  Second-look surgery in patients with ovarian cancer had no significant influence on the relapse-free and overall survival. The 10-year survival was equal in both groups:
  
  
  CONCLUSIONS
  Second-look surgery cannot be justified on the basis of clinically noninvasive methods such as radiological findings with additional use of tumor markers. It should only be done in control clinical trials to evaluate new means of treatment.
authors.affiliation: Universitätsklinik für Frauenheilkunde der Universität Innsbruck, Osterreich, Germany. helmuto@hotmail.com
authors.forename: H W
authors.initials: HW
authors.lastname: Ott
authors.forename: K
authors.initials: K
authors.lastname: Illmensee
authors.forename: A
authors.initials: A
authors.lastname: Zeimet
authors.forename: E
authors.initials: E
authors.lastname: Mueller-Holzner
authors.forename: G
authors.initials: G
authors.lastname: Windbichler
authors.forename: G
authors.initials: G
authors.lastname: Eibl
authors.forename: C
authors.initials: C
authors.lastname: Marth
mesh_terms: D000368:Aged; D018572:Disease-Free Survival; D005185:Fallopian Tube Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000601:surgery*; D016016:Proportional Hazards Models; D015996:Survival Rate