title: Medulloblastoma with extensive nodularity: single photon emission CT study with iodine-123 metaiodobenzylguanidine.
abstract: We present the case of an infant with medulloblastoma with extensive nodularity, which had been called cerebellar neuroblastoma. MR imaging clearly revealed a nodular enhancement, which appeared as a grape-like lesion. Single photon emission CT revealed markedly high iodine-123 metaiodobenzylguanidine uptake in the enhancing tumor. Iodine-123 metaiodobenzylguanidine single photon emission CT may be useful in the diagnosis of medulloblastoma with extensive nodularity, which has been considered to be a subgroup of medulloblastoma with extensive neuronal differentiation.
authors.affiliation: Department of Neurosurgery, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Naitoh
authors.forename: Toshio
authors.initials: T
authors.lastname: Sasajima
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kinouchi
authors.forename: Shigeki
authors.initials: S
authors.lastname: Mikawa
authors.forename: Kazuo
authors.initials: K
authors.lastname: Mizoi
mesh_terms: D019797:3-Iodobenzylguanidine; D001706:Biopsy; D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D007457:Iodine Radioisotopes; D008527:Medulloblastoma / Q000000981:diagnostic imaging* / Q000473:pathology; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine