Psychoactive drug interactions with pharmacotherapy for diabetes.
Diabetes is a common endocrine disorder increasingly encountered in patients requiring treatment with psychoactive drugs. The pharmacotherapy options for diabetes have expanded in recent years and now include 14 oral hypoglycemic drugs from 5 pharmacologic classes, as well as insulin. The diversity of drugs raises the need for clinicians to be aware of potential drug interactions. Fortunately, few drug interactions of major clinical significance involving psychoactive drugs with oral hypoglycemics have been described in the medical literature. The newer drugs for treatment of type 2 diabetes are discussed, and considerations are given for avoiding or minimizing drug interactions when prescribing psychoactive drugs to patients with diabetes.
DeVane
C Lindsay
CL
Department of Psychiatry and Behavioral Sciences, 67 President Street, Medical University of South Carolina, Charleston, SC 29425, USA. devaneL@musc.edu
Markowitz
John S
JS
D000818:Animals; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001523:Mental Disorders / Q000150:complications / Q000188:drug therapy / Q000523:psychology; D011619:Psychotropic Drugs / Q000009:adverse effects* / Q000627:therapeutic use
D007004:Hypoglycemic Agents; D011619:Psychotropic Drugs