Experimental study on the role of Shengfaling tincture in promoting blood circulation and hair growth in rats.
OBJECTIVE
To observe the effect of Shengfaling tincture in promoting blood circulation and hair growth in rats.


METHODS
Rat models of acute blood stasis, hair depilation and qi-deficiency was respectively established, and in each group, the rats were again divided into 3 subgroups which were subjected respectively to treatment with Shengfaling at normal concentration, Shengfaling at half the normal concentration or with 65% ethanol as the control. Observation of the hair growth and blood tests were performed in all the rats.


RESULTS
It was observed that the viscosity ratios of the whole blood and of the plasma, along with the whole blood viscosity and hematocrit, were significantly reduced (P<0.05) in rats with acute blood stasis. In rats with hair depilation, the hair growth was faster in Shengfaling-treated groups than in the control (P<0.001), and a significant reduction in both blood viscosity and hematocrit was observed in rats with qi-deficiency which received Shengfaling treatment (P<0.01).


CONCLUSIONS
Shengfaling Tincture acts to promote blood circulation and hair growth in rats.
Ma
Ping-Bo
PB
Pharmaceutical Department, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
D000818:Animals; D001775:Blood Circulation / Q000187:drug effects*; D001809:Blood Viscosity / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D006197:Hair / Q000187:drug effects* / Q000254:growth & development; D006400:Hematocrit; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D004365:Drugs, Chinese Herbal