Spinal meningioma during hydroxyurea therapy. A paradoxycal case report.
We report the case of a 65-year-old woman who developed symptoms of spinal cord compression due to a spinal meningioma after 10 years of treatment with hydroxyurea (1000 mg/day) for essential thrombocytemia. This case provides a paradigm for the occurrence of symptomatic meningioma in course of HU therapy.
Giordano
F
F
Neurosurgery Unit, Department of Neuroscience, University of Turin, Via Cellini 1, I-10126 Turin, Italy.
Savarino
A
A
Pagni
C A
CA
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002574:Cervical Vertebrae; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use*; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D008579:Meningioma / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D013116:Spinal Cord / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000188:drug therapy*; D017211:Treatment Failure; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D006918:Hydroxyurea