title: Chaperones come of age.
abstract: Chaperone function plays a key role in repairing proteotoxic damage, in the maintenance of cell architecture, and in cell survival. Here, we summarize our current knowledge about changes in chaperone expression and function in the aging process, as well as their involvement in longevity and cellular senescence.
authors.affiliation: Department of Medical Chemistry, Semmelweis University, Budapest, Hungary.
authors.forename: Csaba
authors.initials: C
authors.lastname: Soti
authors.forename: Péter
authors.initials: P
authors.lastname: Csermely
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D031204:Caloric Restriction; D016922:Cellular Senescence / Q000502:physiology*; D006801:Humans; D018832:Molecular Chaperones / Q000502:physiology*; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry / Q000502:physiology
chemical_list: D018832:Molecular Chaperones; D011506:Proteins