title: Hepatocellular carcinoma originating from intramural cells in the bile duct.
abstract: We report a case of intramural hepatocellular carcinoma in the right anterior bile duct associated with another carcinoma in segment IV of the liver. The cancers might have been of multicentric origin because they were separated by about 5 cm of non-cancerous liver parenchyma and their pathological findings were different from each other. The intramural carcinoma pushed up the biliary mucosa and extended into the bile duct lumen. It is difficult to make a reasonable assumption about origin of the tumor, but we consider that the carcinoma might have originated in intramural cells in the bile duct which were different from hepatocytes in the liver parenchyma.
authors.affiliation: Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo University Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. kihase-tky@umin.ac.jp
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kubota
authors.forename: Masaya
authors.initials: M
authors.lastname: Mori
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Midorikawa
authors.forename: Tadatoshi
authors.initials: T
authors.lastname: Takayama
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Makuuchi
mesh_terms: D001650:Bile Duct Neoplasms / Q000473:pathology*; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged