title: Development of a donor-acceptor concept for enzymatic cross-coupling reactions of aldehydes: the first asymmetric cross-benzoin condensation.
abstract: Highly enantioenriched mixed benzoins are obtained selectively through a biocatalytical cross-coupling reaction of aromatic aldehydes using ThDP-dependent enzymes.
authors.affiliation: Institute of Biotechnology 2, Forschungszentrum Jülich, 52425 Jülich, Germany.
authors.forename: Pascal
authors.initials: P
authors.lastname: Dünkelmann
authors.forename: Doris
authors.initials: D
authors.lastname: Kolter-Jung
authors.forename: Adam
authors.initials: A
authors.lastname: Nitsche
authors.forename: Ayhan S
authors.initials: AS
authors.lastname: Demir
authors.forename: Petra
authors.initials: P
authors.lastname: Siegert
authors.forename: Bettina
authors.initials: B
authors.lastname: Lingen
authors.forename: Martin
authors.initials: M
authors.lastname: Baumann
authors.forename: Martina
authors.initials: M
authors.lastname: Pohl
authors.forename: Michael
authors.initials: M
authors.lastname: Müller
mesh_terms: D000446:Aldehyde-Lyases / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D001573:Benzoin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D002262:Carboxy-Lyases / Q000737:chemistry*; D002384:Catalysis; D007700:Kinetics
chemical_list: D001547:Benzaldehydes; D002262:Carboxy-Lyases; C019778:benzoylformate decarboxylase; D000446:Aldehyde-Lyases; C059416:benzaldehyde lyase; D001573:Benzoin