title: Consenting to cornea donation: influencing factors.
abstract: BACKGROUND
  The purpose of the study was to determine factors influencing the decision of the next relative being asked for consent to cornea donation in a prospective, non-comparative case series.
  
  
  METHODS
  Interviews with the relatives of 264 potential cornea donors to the eye bank of the Ludwig-Maximilians-Universität, Munich, were documented following a standardized protocol. The influence of sociological factors on the frequency of obtained consents was investigated by uni- and multivariate analysis.
  
  
  RESULTS
  During a 9-month period, 214 relatives of 264 possible donors were interviewed for consent to cornea donation. In total, 144 consents (67%) and 70 refusals (33%) were obtained; 50 relatives could not be reached. Analysis showed a higher consent rate for donors with a university degree (72%) versus those without (68%). Consent was more often obtained from relatives of donors that were divorced (71%) than from unmarried ones (63%). Husband and wife (71%) consented more frequently to cornea donation than children of age (62%) or parents (58%). Examination of residential area postal codes indicated more frequent refusals from donors of rural (56% consent rate) than urban Munich populations (67% consent rate). The situation was the opposite concerning the residential area of the consenting relative. Postal codes of both the donor and the relative were statistically significant factors in a multiple logistic regression model. There was relatively high willingness to donate in suicides (70%), but not significantly different from other causes like natural deaths (70%) and traffic accidents (66%).
  
  
  CONCLUSIONS
  Some socioeconomic factors such as - in particular - the permanent address of the potential donors and their relatives reflecting a different background and status play an important role in the willingness to donate. A better understanding of this decision making can help the physician to ask more empathically for consent and inform the public more specifically about the donation process.
authors.affiliation: Department of Ophthalmology, Ludwig-Maximilians-Universität, Mathildenstr. 8, 80336, Munich, Germany.
authors.forename: Tina R
authors.initials: TR
authors.lastname: Krieglstein
authors.forename: Ulrich C
authors.initials: UC
authors.lastname: Welge-Lüssen
authors.forename: Siegfried
authors.initials: S
authors.lastname: Priglinger
authors.forename: Anselm
authors.initials: A
authors.lastname: Kampik
authors.forename: Fritz
authors.initials: F
authors.lastname: Priemer
authors.forename: Aljoscha S
authors.initials: AS
authors.lastname: Neubauer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D032962:Consent Forms; D003315:Cornea; D003657:Decision Making; D003710:Demography; D004493:Education; D005190:Family; D005260:Female; D005858:Germany; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D017533:Marital Status; D008875:Middle Aged; D011446:Prospective Studies; D012044:Regression Analysis; D014019:Tissue Donors