Plasma exchange for thrombotic thrombocytopenic purpura: report of 2 cases.
Two patients with thrombotic thrombocytopenic purpura (TTP) were treated with daily plasma exchange with fresh frozen plasma of the plasma volume of the body (40 mg/kg . b.w.), in combination with red blood cell transfusion. The clinical symptoms resolved immediately and the parameters of laboratory examination improved promptly after the treatment, and follow-up of the 2 patients revealed no recurrent TTP episodes. This result indicates that plasma exchange is obviously superior to traditional treatment modalities and has significantly changed the course of TTP.
Yin
Fang
F
Department of Hematology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Meng
Fan-Yi
FY
Zhou
Shu-Yun
SY
Niu
Jing-Na
JN
Li
Jun-Ti
JT
Liu
Fu
F
D000328:Adult; D005260:Female; D006801:Humans; D010951:Plasma Exchange; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy*; D012008:Recurrence; D016896:Treatment Outcome