Vertebrate segmentation: lunatic transcriptional regulation.
Vertebrate segmentation relies on a molecular oscillator, the segmentation clock, which controls the periodic expression of genes such as lunatic fringe in the presomitic mesoderm. Oscillations of lunatic fringe transcripts have now been shown to be controlled at the transcriptional level by clock elements in the lunatic fringe promoter.
Pourquie
Olivier
O
Stowers Institute for Medical Research, Kansas City, MO 64110, USA. olp@stowers-institute.org
D000818:Animals; D005786:Gene Expression Regulation; D012097:Repressor Proteins / Q000378:metabolism; D015534:Trans-Activators / Q000378:metabolism; D014158:Transcription, Genetic; D014714:Vertebrates / Q000033:anatomy & histology* / Q000235:genetics*
D012097:Repressor Proteins; D015534:Trans-Activators