title: Controlling hypertension in patients with diabetes.
abstract: Hypertension and diabetes mellitus are common diseases in the United States. Patients with diabetes have a much higher rate of hypertension than would be expected in the general population. Regardless of the antihypertensive agent used, a reduction in blood pressure helps to prevent diabetic complications. Barring contraindications, angiotensin-converting enzyme inhibitors are considered first-line therapy in patients with diabetes and hypertension because of their well-established renal protective effects. Calcium channel blockers, low-dose diuretics, beta blockers, and alpha blockers have also been studied in this group. Most diabetic patients with hypertension require combination therapy to achieve optimal blood pressure goals.
authors.affiliation: Memorial Family Practice Residency and University of Houston College of Pharmacy, Texas 77074, USA.
authors.forename: Sherri L
authors.initials: SL
authors.lastname: Konzem
authors.forename: Victoria S
authors.initials: VS
authors.lastname: Devore
authors.forename: David W
authors.initials: DW
authors.lastname: Bauer
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000465:Algorithms; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D048909:Diabetes Complications; D003925:Diabetic Angiopathies / Q000517:prevention & control*; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D015438:Health Behavior; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy*; D009765:Obesity; D011945:Receptors, Angiotensin / Q000819:agonists / Q000627:therapeutic use; D014652:Vascular Diseases / Q000209:etiology* / Q000517:prevention & control
chemical_list: D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics; D011945:Receptors, Angiotensin