[Possibilities of immunosuppressive therapy in reconstructive keratoplasty (experience gained in the use of cyclosporin)].
Cyclosporin was used for preventing the graft rejection reaction after reconstructive operations on the anterior segment of the eye. Analysis of the results of surgical treatment of patients with vascularized corneal leukomas of different etiology in 23 patients (25 eyes) who received postoperative oral cyclosporin therapy and in 25 patients to whom this drug was instilled showed that cyclosporin promoted transparent healing of the keratotransplant and its use was not associated with serious side effects.
Kasparov
A A
AA
Aladinskaia
I V
IV
D000368:Aged; D000641:Ammonia; D002057:Burns, Chemical / Q000209:etiology / Q000601:surgery; D016039:Corneal Transplantation; D003524:Cyclosporins / Q000008:administration & dosage / Q000627:therapeutic use*; D005126:Eye Burns / Q000139:chemically induced / Q000601:surgery; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000517:prevention & control*; D006801:Humans; D007049:Iatrogenic Disease; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D013997:Time Factors
D003524:Cyclosporins; D007166:Immunosuppressive Agents; D000641:Ammonia