Behavioral pharmacologists: don't just say "no" to knockout mice. Commentary on Stephens et al. 'Studying the neurobiology of stimulant and alcohol abuse and dependence in genetically manipulated mice'.
Caine
S B
SB
Alcohol and Drug Abuse Research Center, McLean Hospital--Harvard Medical School, Belmont, MA 02478, USA. barak@mclean.harvard.edu
Ralph-Williams
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RJ
D000437:Alcoholism / Q000235:genetics* / Q000378:metabolism / Q000523:psychology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D000697:Central Nervous System Stimulants; D004298:Dopamine / Q000502:physiology; D018390:Gene Targeting; D051379:Mice; D018345:Mice, Knockout / Q000235:genetics*; D008822:Mice, Transgenic / Q000235:genetics*; D011954:Receptors, Dopamine / Q000187:drug effects / Q000235:genetics; D019966:Substance-Related Disorders / Q000235:genetics* / Q000378:metabolism / Q000523:psychology*
D000697:Central Nervous System Stimulants; D011954:Receptors, Dopamine; D004298:Dopamine