title: [Familial idiopathic hypertrophic osteoarthropathy and atopic dermatitis (Currarino's disease)].
abstract: METHODS
  Two brothers with a Currarino's disease are reported. Patients characteristics included a dysmorphic syndrome, cranial suture defects, hypertrophic osteoarthropathy and severe chronic eczema.
  
  
  CONCLUSIONS
  Consanguinity of parents suggests an autosomal recessive inheritance.
  
  
  CONCLUSIONS
  Currarino's disease is a rare unknown constitutional syndrome. The age of beginning of the disease, the cranial suture defects and the chronic eczema allow to distinguish it from the others primary hypertrophic osteoarthropathies.
authors.affiliation: Service de pédiatrie générale et rhumatologie pédiatrique, hôpital Pellegrin-Enfants, place Amélie-Raba-Léon, 33076 Bordeaux, France. pascal.pillet@chu-bordeaux.fr
authors.forename: P
authors.initials: P
authors.lastname: Pillet
authors.forename: F
authors.initials: F
authors.lastname: Boralévi
authors.forename: J F
authors.initials: JF
authors.lastname: Chateil
authors.forename: E
authors.initials: E
authors.lastname: Pinlou
authors.forename: D
authors.initials: D
authors.lastname: Lacombe
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000235:genetics*; D017668:Age of Onset; D003241:Consanguinity; D003393:Cranial Sutures / Q000002:abnormalities*; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000235:genetics*; D003937:Diagnosis, Differential; D005808:Genes, Recessive / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D010004:Osteoarthropathy, Primary Hypertrophic / Q000175:diagnosis / Q000235:genetics*; D013577:Syndrome