title: [Role of coronary artery revascularization and aneurysmectomy in ventricular arrhythmias in the chronic phase of myocardial infarction].
abstract: OBJECTIVE
  The influence of coronary artery revascularization on the control of ventricular arrhythmias in patients with chronic myocardial infarction is uncertain. However, ablation of the arrhythmogenic circuit in these patients by aneurysm resection is useful for controlling ventricular arrhythmias. We made a prospective analysis of our clinical strategy in patients who were candidates for coronary artery revascularization and/or aneurysmectomy to determine its influence on the recurrence of ventricular arrhythmias.
  
  
  METHODS
  Prospective study of 17 consecutive patients with chronic myocardial infarction and ventricular arrhythmias unrelated with an acute ischemic event, who had coronary artery disease and/or ventricular aneurysm susceptible to aggressive treatment. We evaluated our clinical strategy and the recurrence of ventricular arrhythmias during a mean follow-up period of 33.64 months.
  
  
  RESULTS
  Two groups of patients were studied: patients with ventricular aneurysm (group I: 12 patients) and patients without ventricular aneurysm (group II: 5 patients). Seven patients of group I underwent endoaneurysmorrhaphy and endocardial resection (4 of these patients had associated revascularization procedures). Three patients were not candidates for aneurysmectomy or revascularization procedures. Two patients underwent only revascularization procedures. All the patients in group II were revascularized. The patients who underwent aneurysmectomy did not have recurrence of arrhythmias. In 5 of the 6 patients who underwent programmed electrophysiological stimulation after aneurysmectomy, no sustained arrhythmia could be induced. Patients who were only revascularized had a high rate of recurrence of ventricular arrhythmias (57%), which were inducible after revascularization.
  
  
  CONCLUSIONS
  Aneurysmectomy and endocardial resection constituted, in our experience, an effective tool for controlling ventricular arrhythmias associated with left ventricular aneurysm. Coronary artery revascularization in patients with ventricular arrhythmias and chronic myocardial infarction probably does not prevent the recurrence of ventricular arrhythmias.
authors.affiliation: Unidad Médico-Quirúrgica de Cardiología. Hospital Universitario Virgen Macarena. Sevilla. España. afelices@wanadoo.es
authors.forename: Andrés
authors.initials: A
authors.lastname: Felices Nieto
authors.forename: Manuel
authors.initials: M
authors.lastname: Pavón García
authors.forename: José M
authors.initials: JM
authors.lastname: Barquero Aroca
authors.forename: Carlos
authors.initials: C
authors.lastname: Infantes Alcón
authors.forename: Pilar
authors.initials: P
authors.lastname: Nieto Gutiérrez
authors.forename: Francisco
authors.initials: F
authors.lastname: Ruiz Navas
authors.forename: José M
authors.initials: JM
authors.lastname: Cruz Fernández
mesh_terms: D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D002908:Chronic Disease; D017023:Coronary Angiography; D017147:Defibrillators, Implantable; D004594:Electrophysiology; D005260:Female; D005500:Follow-Up Studies; D006322:Heart Aneurysm / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D009204:Myocardial Revascularization; D011446:Prospective Studies; D012008:Recurrence; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control* / Q000628:therapy; D013997:Time Factors; D014693:Ventricular Fibrillation / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control* / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents