title: Composition and antimicrobial activity of the essential oil of Achillea multifida.
abstract: The composition of the water-distilled essential oil of Achillea multifida (DC.) Boiss. (Compositae) was analysed by GC and GC/MS. Fifty-eight compounds were identified representing 93.9 % of the total oil. alpha-Thujone (60.9 %), beta-thujone (9.1 %), sabinene (4.1 %) and camphor (3.7 %) were characterised as the main constituents. The essential oil was tested for its antimicrobial activity using a micro-dilution assay resulting in the inhibition (MIC: 62.5-250 microg/ml) of human pathogenic bacteria and yeast.
authors.affiliation: Medicinal and Aromatic Plant and Drug Research Centre (TBAM), Anadolu University, Eskişehir, Turkey. khcbaser@anadolu.edu.tr
authors.forename: K Hüsnü Can
authors.initials: KH
authors.lastname: Başer
authors.forename: Betül
authors.initials: B
authors.lastname: Demirci
authors.forename: Fatih
authors.initials: F
authors.lastname: Demirci
authors.forename: Serkan
authors.initials: S
authors.lastname: Koçak
authors.forename: Cağri
authors.initials: C
authors.lastname: Akinci
authors.forename: Hulusi
authors.initials: H
authors.lastname: Malyer
authors.forename: Gürcan
authors.initials: G
authors.lastname: Güleryüz
mesh_terms: D031162:Achillea; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D008401:Gas Chromatography-Mass Spectrometry; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010938:Plant Oils