A genomic approach to studying cell-size homeostasis in yeast.
Using a complete set of budding-yeast mutants bearing deletions of all known open reading frames, a recent study has revealed multiple overlapping pathways that coordinately regulate cell-cycle progression with ribosome biogenesis and translation efficiency, providing new insights into the mechanisms governing cell-size homeostasis in eukaryotes..
Millar
Jonathan B A
JB
Division of Yeast Genetics, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK, E-mail: jmillar@nimir.mrc.ac.uk
D002453:Cell Cycle / Q000235:genetics; D002455:Cell Division / Q000235:genetics; D015966:Gene Expression Regulation, Fungal; D016681:Genome, Fungal; D006706:Homeostasis / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics*