title: New dithiolopyrrolone antibiotics from Saccharothrix sp. SA 233. II. Physicochemical properties and structure elucidation.
abstract: Three new natural dithiopyrrolone antibiotics, 3-methyl-2-butenoylpyrrothine (1), tigloylpyrrothine (2), and n-butyropyrrothine (3) were isolated along with the known isobutyropyrrothine (4) and thiolutin (5) from the fermentation broth of Saccharothrix sp. SA 233. The structures of the novel compounds were established on the basis on their spectral data.
authors.affiliation: Laboratoire de Recherche sur les Produits Bioactifs et al Valorisation de la Biomasse, Ecole Normale Supérieure de Kouba, Alger, Algérie.
authors.forename: Lynda
authors.initials: L
authors.lastname: Lamari
authors.forename: Abdelghani
authors.initials: A
authors.lastname: Zitouni
authors.forename: Tahar
authors.initials: T
authors.lastname: Dob
authors.forename: Nasserdine
authors.initials: N
authors.lastname: Sabaou
authors.forename: Ahmed
authors.initials: A
authors.lastname: Lebrihi
authors.forename: Pierre
authors.initials: P
authors.lastname: Germain
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Seguin
authors.forename: François
authors.initials: F
authors.lastname: Tillequin
mesh_terms: D000192:Actinomycetales / Q000254:growth & development / Q000378:metabolism* / Q000502:physiology; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D009682:Magnetic Resonance Spectroscopy; D011760:Pyrrolidinones / Q000737:chemistry*; D019265:Spectroscopy, Near-Infrared
chemical_list: C467212:3-methyl-2-butenoylpyrrothine; D000900:Anti-Bacterial Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D011760:Pyrrolidinones; C467215:iso-butyropyrrothine; C467213:n-butyropyrrothine; C467214:tigloylpyrrothine; C006361:acetopyrrothine