A case of partial mole and atypical type I triploidy associated with severe HELLP syndrome at 18 weeks' gestation.
Partial mole is a rare complication of pregnancy and 90% of cases are associated with triploidy. HELLP syndrome is also a rare and life-threatening condition that occurs after 20 weeks' gestation. We report a case presenting with a combination of severe HELLP syndrome, partial mole, triploidy type I and fetal growth restriction at 18 weeks' gestation. Partial mole and any type of triploidy must be considered in cases of hydrocephalus and severe growth restriction in the second trimester of pregnancy. Our case highlights the fact that growth restriction can be associated with type I triploidy and that severe HELLP syndrome can develop in such cases even before 20 weeks' gestation.
Stefos
T
T
UVa Health System, Department of Obstetrics and Gynecology, University of Virginia, Charlottesville 22908, USA. thstefos@cc.uoi.grorts9u@virginia.edu
Plachouras
N
N
Mari
G
G
Cosmi
E
E
Lolis
D
D
D002869:Chromosome Aberrations; D015897:Comorbidity; D005260:Female; D005317:Fetal Growth Retardation / Q000235:genetics*; D017359:HELLP Syndrome / Q000453:epidemiology* / Q000235:genetics; D006801:Humans; D006828:Hydatidiform Mole / Q000453:epidemiology* / Q000235:genetics; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D016216:Ultrasonography, Prenatal; D014594:Uterine Neoplasms / Q000453:epidemiology* / Q000235:genetics