title: Acute pancreatitis: a prospective study of its incidence, aetiology, severity, and mortality in Iceland.
abstract: OBJECTIVE
  To evaluate the incidence, aetiology, severity and mortality of patients with acute pancreatitis.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  University hospital, Iceland.
  
  
  METHODS
  All 50 patients diagnosed with acute pancreatitis during the one-year period October 1998-September 1999 inclusive.
  
  
  METHODS
  APACHE II, and Ranson and Imrie scores, and C-reactive protein (CRP) concentrations. The Balthazar-Ranson criteria were used for scoring of computed tomograms (CT).
  
  
  RESULTS
  27 of the 50 patients were male. The median age of the whole series was 60 years (range 19-85). The estimated incidence was 32/100000 for the first attack of acute pancreatitis. The causes were; gallstones 21 (42%), alcohol 16 (32%), miscellaneous 12 (24%), and idiopathic 1 (2%). 15 (33%) of the patients had APACHE II scores > or = 9, 17 (38%) had Ranson scores of > or = 3, 23 (50%) had Imrie scores of > or = 3, and 16 (34%) had CRP concentrations over 210 mg/L during the first 4 days or > 120 mg/L during the first week. Seven patients had severe pancreatitis. 2 patients in the whole group died, and both had clinically severe pancreatitis.
  
  
  CONCLUSIONS
  This study indicates that the incidence of less severe acute pancreatitis is rising. Prospective assessment makes it possible to evaluate the aetiological factors more accurately. Measurement of the CRP concentration is an attractive and simple alternative to the severity scoring systems currently in use.
authors.affiliation: Department of Surgery, Landspítali - University Hospital, Reykjavík, Iceland.
authors.forename: H
authors.initials: H
authors.lastname: Birgisson
authors.forename: P H
authors.initials: PH
authors.lastname: Möller
authors.forename: S
authors.initials: S
authors.lastname: Birgisson
authors.forename: A
authors.initials: A
authors.lastname: Thoroddsen
authors.forename: K S
authors.initials: KS
authors.lastname: Asgeirsson
authors.forename: S V
authors.initials: SV
authors.lastname: Sigurjónsson
authors.forename: J
authors.initials: J
authors.lastname: Magnússon
mesh_terms: D018806:APACHE; D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007055:Iceland / Q000453:epidemiology; D015994:Incidence; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D011446:Prospective Studies