Albumin-coated knitted Dacron aortic prosthses. Study of postoperative inflammatory reactions.
BACKGROUND
The purpose of this study was to investigate the postoperative inflammatory reactions to albumin-coated Dacron grafts (ACGs), which are used in the repair of abdominal aortic aneurysm (AAA).


METHODS



METHODS
a retrospective study with a follow-up period of 14 days.


METHODS
University hospital.


METHODS
50 patients admitted for elective AAA repair from January 1997 to January 2000.


METHODS
each patient underwent AAA repair with an ACG (Bard, albumin-coated Dacron graft).


METHODS
the white blood cell (WBC) count, plasma C-reactive protein (CRP) concentration, and body temperature (BT) were determined. The preoperative data, the highest values of the postoperative data, and the values 2 weeks postsurgery were analyzed.


RESULTS
The BT, CRP, and WBC increased and peaked at the 1st week postsurgery and then decreased gradually. The BT and WBC levels returned to normal within 2 weeks. The CRP level continued to show slightly elevated values in the 2nd week, but it was not significantly different compared to the preoperative data.


CONCLUSIONS
The use of an albumin-impregnated prosthesis for the reconstruction of AAA is biocompatible, since no significant increases in inflammatory reactions are observed in the 2nd week postsurgery.
Kudo
F A
FA
Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Hokkaido, Japan.
Nishibe
T
T
Miyazaki
K
K
Flores
J
J
Yasuda
K
K
D000368:Aged; D000369:Aged, 80 and over; D000418:Albumins / Q000009:adverse effects*; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D020099:Coated Materials, Biocompatible / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011093:Polyethylene Terephthalates / Q000009:adverse effects*; D011183:Postoperative Complications; D012189:Retrospective Studies; D013997:Time Factors
D000418:Albumins; D020099:Coated Materials, Biocompatible; D011093:Polyethylene Terephthalates