Peptidomimetics and peptide backbone modifications.
The replacement of the amide bond in a peptide backbone is a widely used form of peptide mimicry. Several of the most common amide bond surrogates, including peptidomimetic work done in this laboratory, and their biological applications are presented in this review.
Ahn
Jung-Mo
JM
Department of Chemistry, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA.
Boyle
Nicholas A
NA
MacDonald
Mary T
MT
Janda
Kim D
KD
D000596:Amino Acids / Q000737:chemistry; D007202:Indicators and Reagents; D018716:Molecular Mimicry; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry
D000596:Amino Acids; D007202:Indicators and Reagents; D010455:Peptides