Ceramide in apoptosis: a revisited role.
The sphingolipid ceramide has recently emerged as a new transducer or modulator of apoptotic cell death. This function, however, has recently been challenged. Here, in the light of recent observations, the role of ceramide in apoptosis signaling is discussed.
Levade
Thierry
T
INSERM U.466, Laboratoire de Biochimie, CHU Rangueil, Toulouse, France. levade@toulouse.inserm.fr
Malagarie-Cazenave
Sophie
S
Gouazé
Valérie
V
Ségui
Bruno
B
Tardy
Claudine
C
Betito
Susan
S
Andrieu-Abadie
Nathalie
N
Cuvillier
Olivier
O
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002518:Ceramides / Q000502:physiology*; D006801:Humans
D002518:Ceramides