title: Czech miner studies of lung cancer risk from radon.
abstract: Epidemiological evidence of lung cancer risk from radon is based mainly on studies of miners. Two such studies among Czech uranium miners were established in 1970 and 1980. A subcohort of 5002 miners and a nested-in case-control study contribute to a joint European project. In this paper, the subcohort of miners with 495 lung cancers is described. The excess relative risk depends linearly on cumulative exposure incurred more than 5 years before. The relative effect from exposures in the distant past decreases by 62% per decade. Simultaneously, the excess relative risk is lower by 43% per decade in dependence on age at exposure. The effect of smoking, partly analysed in the study, suggests a twofold elevation in the relative risk coefficient among non-smokers, but this difference is not significant.
authors.affiliation: National Radiation Protection Institute, Prague, Czech Republic.
authors.forename: L
authors.initials: L
authors.lastname: Tomásek
mesh_terms: D000328:Adult; D000368:Aged; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000396:Air Pollutants, Radioactive / Q000009:adverse effects*; D016022:Case-Control Studies; D015331:Cohort Studies; D018153:Czech Republic; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D008906:Mining; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D009784:Occupational Diseases / Q000209:etiology*; D016273:Occupational Exposure; D011829:Radiation Dosage; D011886:Radon / Q000009:adverse effects*; D012307:Risk Factors; D014501:Uranium
chemical_list: D000395:Air Pollutants, Occupational; D000396:Air Pollutants, Radioactive; D014501:Uranium; D011886:Radon