title: Visualization of microvascularity in glioblastoma multiforme with 8-T high-spatial-resolution MR imaging.
abstract: We used 8-T high-spatial-resolution gradient-echo MR imaging to directly visualize microvascularity in pathologically proved glioblastoma multiforme. Images were compared with 1.5-T high-spatial-resolution fast spin-echo T2-weighted images and digital subtraction angiograms. Preliminary data indicate that 8-T high-spatial-resolution MR imaging may enable the identification of areas of abnormal microvascularity in glioblastoma multiforme that are not visible with other routine clinical techniques.
authors.affiliation: Department of Radiology, the Ohio State University Medical Center, 168 Means Hall, 1654 Upham Drive, Columbus, OH 43221, USA.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Christoforidis
authors.forename: John C
authors.initials: JC
authors.lastname: Grecula
authors.forename: Herbert B
authors.initials: HB
authors.lastname: Newton
authors.forename: Allahyar
authors.initials: A
authors.lastname: Kangarlu
authors.forename: Amir M
authors.initials: AM
authors.lastname: Abduljalil
authors.forename: Petra
authors.initials: P
authors.lastname: Schmalbrock
authors.forename: Donald W
authors.initials: DW
authors.lastname: Chakeres
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D001932:Brain Neoplasms / Q000098:blood supply* / Q000175:diagnosis / Q000000981:diagnostic imaging; D005909:Glioblastoma / Q000098:blood supply* / Q000175:diagnosis / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008833:Microcirculation / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000175:diagnosis / Q000000981:diagnostic imaging