Pathogenesis of nontuberculous mycobacteria infections.
M avium is a microorganism well adapted to living in the environment and in different hosts. During the past 15 years, a substantial amount of information has been accumulated about the mechanisms used by M avium to cross the host's mucosal barrier, replicate inside cells, circumvent the host's immune response, and persist inside the host. It turns out that M avium is a fascinating pathogen after all. The increasing knowledge about M avium pathogenesis may one day provide means for a more effective prophylaxis as well as for treatment of the infection.
McGarvey
Jeffery
J
Kuzell Institute, California Pacific Medical Center Research Institute, 2200 Webster Street, Suite 305, San Francisco, CA 94115, USA.
Bermudez
Luiz E
LE
D006801:Humans; D009092:Mucous Membrane / Q000382:microbiology; D009165:Mycobacterium Infections, Nontuberculous / Q000382:microbiology*; D009170:Nontuberculous Mycobacteria / Q000472:pathogenicity*; D020545:Respiratory Mucosa / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000382:microbiology