Clinical outcome and neuropsychological deficits after right decompressive hemicraniectomy in MCA infarction.
OBJECTIVE
The purpose of this study was to analyse in detail the functional outcome and the neuropsychological deficits in patients with space-occupying infarction of the non-dominant hemisphere one year after surgery.


METHODS
Postoperative complications and retrospective consent to surgery were assessed in a semi-structured interview in 26 patients. Functional outcome was measured with the Barthel-Index (BI) and Rankin-Scale. Neuropsychological tests in 14 patients focused on visuo-spatial and visuo-constructive abilities, attention, spatial span and self-rated mood.


RESULTS
The one-year survival rate was 69 % (18 of 26). The functional outcome was good (BI >/= 90) in 3 patients, fairly good (BI 75-85) in 6, moderate (BI 30-70) in 6, and poor (BI 0-25) in 3 patients. Age was an independent predictor of outcome, patients above 52 years had a BI of 50 or below. Neuropsychological tests (14 of 18) showed profound attention deficits in all patients, and visuo-spatial and visuo-constructive deficits in patients with lower formal education. Retrospectively, 4 of 18 patients would not give consent to surgery again, mostly because of the bad quality of life postoperatively.


CONCLUSIONS
Older patients do not seem to benefit from decompressive hemicraniectomy; more than half of the surviving younger patients have a good outcome and live independently. Attention deficits are prominent in all patients; visuo-spatial and constructive deficits are less pronounced in patients with higher formal education. Retrospective agreement to decompressive hemicraniectomy is high in patients with good functional outcome.
Leonhardt
Georg
G
Klinik und Poliklinik für Neurologie, Martin-Luther-Universität, Halle-Wittenberg, 06097 Halle/Saale, Germany.
Wilhelm
Hans
H
Doerfler
Arnd
A
Ehrenfeld
Christiane E
CE
Schoch
Beate
B
Rauhut
Friedhelm
F
Hufnagel
Andreas
A
Diener
Hans Christoph
HC
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D003399:Craniotomy / Q000009:adverse effects; D019299:Decompression, Surgical / Q000009:adverse effects; D005260:Female; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000150:complications / Q000401:mortality / Q000503:physiopathology* / Q000601:surgery*; D007258:Informed Consent; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011183:Postoperative Complications / Q000209:etiology; D011788:Quality of Life / Q000523:psychology; D012189:Retrospective Studies; D016896:Treatment Outcome