title: Idiopathic paroxysmal kinesigenic choreoathetosis: precipitation of attacks by vestibular stimulation.
abstract: A 24-year-old woman presented with a 3.5-year history of paroxysmal dystonia that was precipitated by sudden movement, especially when she started to walk. It was characterised by shrugging of shoulders, flexion of the neck and thoracic spine, and stiffness of the right leg followed by falls. Each attack lasted for less than 5min. Inadequate sleep and stress were exacerbating factors. There was no similar family history. Physical examination and investigations were normal. The following manoeuvres that caused vestibular stimulation precipitated attacks: turning her head from side to side while standing still, sitting still on a rotating chair and an ice-water caloric test. She had partial responses to phenytoin and levodopa, and a good response to haloperidol. Vestibular stimulation as a precipitating factor in paroxysmal kinesigenic choreoathetosis has not been reported previously.
authors.affiliation: Division of Neurology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia. nkchew33@hotmail.com
authors.forename: Nee-Kong
authors.initials: NK
authors.lastname: Chew
authors.forename: Chong-Tin
authors.initials: CT
authors.lastname: Tan
authors.forename: Khean-Jin
authors.initials: KJ
authors.lastname: Goh
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D001264:Athetosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D002819:Chorea / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D010812:Physical Stimulation; D012008:Recurrence; D014722:Vestibule, Labyrinth / Q000502:physiology*
chemical_list: D000927:Anticonvulsants