title: Development of a diffusive sampling method for determination of methyl isocyanate in air.
abstract: A diffusive sampling method for determination of methyl isocyanate in air has been developed. A glass fibre filter impregnated with 1-(2-methoxyphenyl)piperazine in a commercially available diffusive sampling device was used to collect methyl isocyanate and the derivative formed was analysed with LC-MS/MS. The sampling rate was determined to be 15.6 ml min(-1), with a relative standard deviation of 7.3%. The sampler was validated for sampling periods from 15 min to 8 h, for relative humidities from 20% to 80% and for concentrations from I to 46 microg m(-3). A field validation was also made and the diffusive sampling results showed no difference compared to a pumped reference method. The impregnated filters have to be stored apart from the diffusive sampler housing and loaded into the sampler prior to each sampling.
authors.affiliation: National Institute for Working Life, Umeå, Sweden. peter.von.zweigbergk@niwl.se
authors.forename: Peter
authors.initials: P
authors.lastname: von Zweigbergk
authors.forename: Roger
authors.initials: R
authors.lastname: Lindahl
authors.forename: Anders
authors.initials: A
authors.lastname: Ostin
authors.forename: Jenny
authors.initials: J
authors.lastname: Ekman
authors.forename: Jan-Olof
authors.initials: JO
authors.lastname: Levin
mesh_terms: D016902:Air Pollution, Indoor / Q000032:analysis*; D000986:Antisickling Agents / Q000032:analysis*; D004058:Diffusion; D004784:Environmental Monitoring / Q000295:instrumentation*; D006801:Humans; D017953:Isocyanates / Q000032:analysis*; D016273:Occupational Exposure; D012016:Reference Values; D013048:Specimen Handling
chemical_list: D000986:Antisickling Agents; D017953:Isocyanates; C008461:methyl isocyanate