Fractionated stereotactic radiotherapy for acoustic neuromas.
Fractionated stereotactic radiotherapy (FSR) for acoustic neuromas offers both higher tumor dose and potential sparing of the facial and auditory cranial nerve functions. Eighty consecutive patients (45 males and 35 females; age 56.8 +/- 1.7 years) received FSR for acoustic neuromas and had a median follow-up of 2.9 years (range 2.3-6.5 years). For FSR, 70 patients had 5 daily fractions of 5 Gy (25 Gy total) and 10 patients had 10 daily fractions of 3 Gy (30 Gy total). Volume decreased by an average of 18%. No tumor increased in size, no patient developed facial weakness, and hearing was preserved.
Williams
Jeffery A
JA
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D016001:Confidence Intervals; D003391:Cranial Nerves / Q000473:pathology / Q000502:physiology / Q000601:surgery; D019583:Dose Fractionation, Radiation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000175:diagnosis / Q000601:surgery*; D016634:Radiosurgery / Q000379:methods* / Q000706:statistics & numerical data