Light-induced helix formation.
This study shows that incorporation of [Rub2m-OH]2+ at the N-terminus of the Fs peptide enhances its stability by approximately 0.15 kcal/mol through the mechanism of dipole-dipole coupling at the excited state, suggesting that photoinduced charge generation at a well-controlled and specific location provides a convenient means to trigger helix-coil transition on nanosecond or even faster time scales.
Huang
Cheng-Yen
CY
Department of Chemistry, University of Pennsylvania, Philadelphia 19104, USA.
He
Shu
S
DeGrado
William F
WF
McCafferty
Dewey G
DG
Gai
Feng
F
D007700:Kinetics; D008027:Light; D009842:Oligopeptides / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry; D017510:Protein Folding; D017433:Protein Structure, Secondary / Q000528:radiation effects*; D012428:Ruthenium / Q000737:chemistry; D013055:Spectrophotometry, Infrared
D009842:Oligopeptides; D009942:Organometallic Compounds; D012428:Ruthenium