title: Phytochemical study on American plants I. Two new phenol glucosides, together with known biflavones and diterpene, from leaves of Juniperus occidentalis Hook.
abstract: Two new phenol glucosides termed juniperosides I (1) and II (2) were isolated, together with known two biflavones, cupressuflavone and amentoflavone and a diterpene, 3beta-hydroxy sandaracopimaric acid, from leaves of Juniperus occidentalis HOOK. (Cupressaceae) collected in Oregon, U.S.A., and their structures were established as (1S)- and (1R)-1-(2'-hydroxy-6'-methylphenyl)ethanol 2'-O-beta-D-glucopyranosides (1, 2), respectively, on the basis of spectral, chemical, and synthetic evidence. The glycosides 1 and 2, as well as the corresponding aglycones 1a and 2a, are apparently novel types of naturally occurring compounds; to our knowledge, isolation of these types of natural phenol derivatives has only rarely been reported from the vegetable kingdom.
authors.affiliation: Faculty of Pharmaceutical Sciences, Setsunan University, Hirikata, Osaka, Japan. nakanisi@pharm.setsunan.ac.jp
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nakanishi
authors.forename: Yuka
authors.initials: Y
authors.lastname: Inatomi
authors.forename: Hiroko
authors.initials: H
authors.lastname: Murata
authors.forename: Naoki
authors.initials: N
authors.lastname: Iida
authors.forename: Akira
authors.initials: A
authors.lastname: Inada
authors.forename: Frank A
authors.initials: FA
authors.lastname: Lang
authors.forename: Jin
authors.initials: J
authors.lastname: Murata
mesh_terms: D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D018653:Juniperus / Q000737:chemistry*; D009656:North America; D019800:Phenol / Q000737:chemistry* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D014481:United States
chemical_list: D004224:Diterpenes; D005419:Flavonoids; D005960:Glucosides; D010936:Plant Extracts; D019800:Phenol