Epithelioid hemangioendothelioma of the liver associated with thrombocytopenia and coagulopathy.
Epithelioid hemangioendothelioma of the liver is a rare vascular neoplasm with intermediate malignant potential. The prognosis is highly unpredictable. We report the case of a 59-year-old woman who had the tumor radically resected, but multiple metastases of the liver developed associated with thrombocytopenia and consumption coagulopathy, as observed in Kasabach-Merritt syndrome. The patient did not respond to any treatment and the behavior of the tumor was very aggressive. The patient died 15 months after radical resection of the tumor.
Imanishi
H
H
Department of Surgery, Yokohama Seamen's Insurance Hospital, 43-1 Kamadai-cho, Hodogaya-ku, Yokohama, Kanagawa 240-8585, Japan. imanishi-tky@umin.ac.jp
Kawata
M
M
Yanagihara
M
M
Nakayama
N
N
Sato
T
T
Furukawa
Y
Y
Fukunaga
N
N
Kozuma
T
T
D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000175:diagnosis; D017809:Fatal Outcome; D005260:Female; D006390:Hemangioendothelioma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications* / Q000175:diagnosis