title: Neostigmine for the treatment of pediatric acute colonic pseudo-obstruction.
abstract: Acute colonic pseudo-obstruction (ie, Ogilvie's syndrome) is an uncommon but serious condition in the pediatric population. Definitive management traditionally has consisted of endoscopic decompression. Recent studies have documented the effectiveness of neostigmine as a pharmacologic alternative to mechanical decompression. To date, however, this literature has focused exclusively on the adult population. The authors present the first reported case of the successful administration of neostigmine to treat acute colonic pseudo-obstruction in a child.
authors.affiliation: Department of Surgery, Queen's University School of Medicine, Kingston, Ontario, Canada.
authors.forename: Scott
authors.initials: S
authors.lastname: Gmora
authors.forename: Dan
authors.initials: D
authors.lastname: Poenaru
authors.forename: Ellen
authors.initials: E
authors.lastname: Tsai
mesh_terms: D002675:Child, Preschool; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D003112:Colonic Pseudo-Obstruction / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D009388:Neostigmine / Q000627:therapeutic use*; D012307:Risk Factors
chemical_list: D002800:Cholinesterase Inhibitors; D009388:Neostigmine