title: Speckle-contrast monitoring of tissue thermal modification.
abstract: Measurements of the contrast value of time-averaged speckle-modulated images of cartilage tissue are used to study tissue thermal modification in the case of laser-light treatment. This modification is related to thermally induced internal stress relaxation in the matrix of the treated tissue. The specific feature of the evolution of time-averaged speckle contrast with a change in the current temperature of modified collagen tissue is the typical looplike form of the contrast-temperature dependencies associated with irreversible changes in tissue structure and correlated with changes in the tissue diffuse transmittance and the tissue internal stress mentioned by other researchers.
authors.affiliation: Department of Optics, Saratov State University, Russia. zimnykov@sgu.ssu.runnet.ru
authors.forename: Dmitry A
authors.initials: DA
authors.lastname: Zimnyakov
authors.forename: Dmitry N
authors.initials: DN
authors.lastname: Agafonov
authors.forename: Alexander P
authors.initials: AP
authors.lastname: Sviridov
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Omel'chenko
authors.forename: Liana V
authors.initials: LV
authors.lastname: Kuznetsova
authors.forename: Victor N
authors.initials: VN
authors.lastname: Bagratashvili
mesh_terms: D000818:Animals; D002356:Cartilage / Q000502:physiology* / Q000528:radiation effects*; D006358:Hot Temperature; D066298:In Vitro Techniques; D007834:Lasers; D013552:Swine; D013696:Temperature; D013997:Time Factors