title: Primary anti-phospholipid antibody syndrome caused by isolated anti-phosphatidylethanolamine antibodies presenting as cryptogenic fibrosing alveolitis with recurrent pulmonary hemorrhage after single-lung transplantation.
abstract: A 28-year-old man underwent a single-lung transplantation for rapidly progressive usual interstitial pneumonitis. Following transplantation, primary anti-phospholipid antibody syndrome was diagnosed after a thromboembolic event and continued dyspnea. Review of his native lung and allograft tissue showed diffuse hemorrhage secondary to capillary injury, probably reflecting anti-phospholipid antibody effects on endothelia.
authors.affiliation: Department of Pathology, Ohio State University, Columbus, Ohio 43210, USA.
authors.forename: Cynthia M
authors.initials: CM
authors.lastname: Magro
authors.forename: Amy
authors.initials: A
authors.lastname: Pope-Harman
authors.forename: Patrick
authors.initials: P
authors.lastname: Moh
authors.forename: Patrick
authors.initials: P
authors.lastname: Ross
mesh_terms: D000328:Adult; D000906:Antibodies; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000276:immunology*; D004730:Endothelium, Vascular / Q000276:immunology; D006470:Hemorrhage / Q000276:immunology / Q000473:pathology; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000601:surgery*; D016040:Lung Transplantation / Q000276:immunology; D008297:Male; D010714:Phosphatidylethanolamines / Q000276:immunology*; D011658:Pulmonary Fibrosis / Q000276:immunology / Q000473:pathology
chemical_list: D000906:Antibodies; D010714:Phosphatidylethanolamines