Diagnosis and treatment of primary gastric non-Hodgkin's lymphoma: analysis of 157 patients.
OBJECTIVE
To seek the optimum treatment for patients with primary gastric non-Hodgkin's lymphoma and factors associated with prognosis.


METHODS
A retrospective study was conducted on 157 primary gastric non-Hodgkin's lymphoma patients who had received operation for 45 years.


RESULTS
The X-ray diagnosis rate was 39.4% before operation. The diagnosis rate by gastroscopy was 52.7%. Among the 157 patients, 32 belonged to stage I(E), 40 stage II(E), 29 stage III(E), and 56 stage IV(E). All of the patients were received chemotherapy or radiation. The 3-, 5-, 10-, 15-year survival rates were 51.1% (69/135), 42.3% (55/130), 20.7% (23/111), and 13.5% (14/104).


CONCLUSIONS
The 3-, 5-year survival rates in stage I(E) and stage II(E) were 2 to 5 times higher than those in stage III(E) and IV(E) (P < 0.01). The 3-, 5-year survival rates of primary gastric non-Hodgkin's lymphoma were 60.2% (65/108) and 50.0% (52/104) respectively. The prognosis was better than the 5-year survival rate of gastric cancer patients with D(2) lymphodenectomy (33.3%). Early diagnosis and treatment are effective to prevent complications, enhance quality of patient's life, and prolong the survival.
Cui
Qinghao
Q
Department of Abdominal Surgery, Cancer Hospital, Tianjin Medical University, Tianjin 300060, China.
Dong
Xuebin
X
Wang
Dianchang
D
Hao
Xishan
X
Wang
Jiacang
J
Li
Qiang
Q
Kong
Dalu
D
Liu
Ning
N
D006801:Humans; D008228:Lymphoma, Non-Hodgkin; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate