Asymmetric epoxidation via phase-transfer catalysis: direct conversion of allylic alcohols into alpha,beta-epoxyketones.
Studies into the use of a chiral phase-transfer catalyst in conjunction with sodium hypochlorite to effect the enantio-selective formation of alpha,beta-epoxyketones from allylic alcohols are described.
Lygo
Barry
B
School of Chemistry, University of Nottingham, Nottingham, UK NG7 2RD. b.lygo@nottingham.ac.uk
To
Daniel C M
DC