title: Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia.
abstract: Extracts of the marine sponge Caminus sphaeroconia showed potent activity in a screen for bacterial type III secretion inhibitors. Bioassay guided fractionation of the extract led to the isolation of the novel antimicrobial glycolipid caminoside A (1). The structure of caminoside A was elucidated by analysis of spectroscopic data and chemical degradation.[structure: see text]
authors.affiliation: Department of Chemistry, University of British Columbia, Vancouver, B.C., V6T 1Z1, Canada.
authors.forename: Roger G
authors.initials: RG
authors.lastname: Linington
authors.forename: Marilyn
authors.initials: M
authors.lastname: Robertson
authors.forename: Annick
authors.initials: A
authors.lastname: Gauthier
authors.forename: B Brett
authors.initials: BB
authors.lastname: Finlay
authors.forename: Rob
authors.initials: R
authors.lastname: van Soest
authors.forename: Raymond J
authors.initials: RJ
authors.lastname: Andersen
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification*; D002236:Carbohydrate Conformation; D003503:Cyclobutanes / Q000138:chemical synthesis* / Q000737:chemistry; D005947:Glucose / Q000737:chemistry; D006017:Glycolipids / Q000737:chemistry / Q000302:isolation & purification*; D008958:Models, Molecular; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D003503:Cyclobutanes; D006017:Glycolipids; D013449:Sulfonamides; C469706:triethylmethylsulfinamide; D005947:Glucose; C058254:sibutramine