Disturbances of saccadic eye movements in monkeys during development of MPTP-induced syndrome.
Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP-syndrome. Different disturbances of large- and small-scale saccades were found.
Tereshchenko
L V
LV
Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov Moscow State University. lter@protein.bio.msu.ru
Yudin
A G
AG
Kuznetsov
YuB
Y
Latanov
A V
AV
Shul'govskii
V V
VV
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Q000008:administration & dosage; D000818:Animals; D008251:Macaca; D020734:Parkinsonian Disorders; D011930:Reaction Time; D012438:Saccades / Q000502:physiology*
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine