Muscle-fiber characteristics in adult mouse-tongue muscles.
To clarify functions of the mouse-tongue muscles, proteins such as myocin heavy chain (MHC) 2a and MHC-2b, which are isoforms of the fast-twitch fiber type myosin heavy chain, in the lateral margin of the tongue were observed by reverse transcription polymerase chain reaction and immunohistochemical analyses. The main MHC isoform in the superior longitudinal muscle of the tongue was MHC-2b, with the fastest function and the main MHC isoform in the transverse muscle of the tongue was MHC-2a. These findings suggested that the fastest function is necessary for the superior longitudinal muscle of the tongue, which is useful for moving the tongue in and out of the mouth in the sagittal direction, showing different cellular biological properties of the myofibers from those of the transverse muscle of the tongue.
Abe
Shinichi
S
Oral Health Science Center, Department of Anatomy, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan. shinabe@tdc.ac.jp
Maejima
Masayo
M
Watanabe
Hiroki
H
Shibahara
Takahiko
T
Agematsu
Hiroko
H
Doi
Tomoyoshi
T
Sakiyama
Koji
K
Usami
Atsushi
A
Gojyo
Kazuro
K
Hashimoto
Masatsugu
M
Yoshinari
Masao
M
Ide
Yoshinobu
Y
D000818:Animals; D018076:DNA, Complementary / Q000032:analysis; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018656:Muscle Fibers, Fast-Twitch / Q000145:classification / Q000166:cytology / Q000378:metabolism; D018657:Muscle Fibers, Slow-Twitch / Q000145:classification / Q000166:cytology / Q000378:metabolism; D018482:Muscle, Skeletal / Q000166:cytology / Q000378:metabolism*; D009218:Myosins / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D020033:Protein Isoforms; D012333:RNA, Messenger / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014059:Tongue / Q000166:cytology*
D018076:DNA, Complementary; D020033:Protein Isoforms; D012333:RNA, Messenger; D009218:Myosins