title: Supine hypertension during general anesthesia in a patient taking midodrine.
abstract: Midodrine, a drug used to treat symptomatic orthostatic hypotension, may cause or exacerbate supine hypertension. We describe a case of a patient taking midodrine who exhibited severe hypertension during general anesthesia. Possible preventive measures to avoid this complication are discussed.
authors.affiliation: Department of Anesthesia, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA. kathleen.h.chaimberg@hitchcock.org
authors.forename: Kathleen H
authors.initials: KH
authors.lastname: Chaimberg
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Travis
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D000768:Anesthesia, General; D001794:Blood Pressure / Q000502:physiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000139:chemically induced* / Q000503:physiopathology; D007866:Leg; D008297:Male; D008879:Midodrine / Q000009:adverse effects*; D011187:Posture / Q000502:physiology; D016683:Supine Position / Q000502:physiology*; D013530:Surgical Wound Infection / Q000150:complications / Q000601:surgery; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
chemical_list: D014662:Vasoconstrictor Agents; D008879:Midodrine