Spring forward and fall back: dynamics in formation of somite boundaries.
Oscillating signaling systems mediate the progressive division of mesoderm into segmental units, termed somites. A recent study using time-lapse analysis in living chick embryos has revealed that the process of somite boundary formation relies on a carefully choreographed series of cell movements, which are both unexpected and surprisingly intricate.
Krumlauf
Robb
R
Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
D000818:Animals; D002465:Cell Movement; D015870:Gene Expression; D020869:Gene Expression Profiling; D008648:Mesoderm / Q000166:cytology / Q000502:physiology*; D036122:Receptor, EphA4 / Q000235:genetics*; D015398:Signal Transduction; D019170:Somites / Q000166:cytology / Q000502:physiology*
D036122:Receptor, EphA4