Nutrient-regulated protein kinases in budding yeast.
The ability of cells to react appropriately to nutritional cues is of fundamental importance, and in budding yeast, a small number of intracellular protein kinases, PKA, Snf1p/AMP-activated kinase, TOR, Gcn2p, and the cyclin-dependent kinase Pho85p have key roles. A recently characterized enzyme, PAS kinase, may be a new member of this group of nutritional transducers.
Wilson
Wayne A
WA
Department of Biochemistry and Molecular Biology, Center for Diabetes Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Roach
Peter J
PJ
D000596:Amino Acids; D018797:Cell Cycle Proteins; D018844:Cyclin-Dependent Kinases / Q000235:genetics; D005656:Fungal Proteins / Q000502:physiology; D005947:Glucose / Q000502:physiology; D009584:Nitrogen / Q000502:physiology; D009751:Nutritional Requirements; D028061:Phosphate Transport Proteins / Q000235:genetics; D010710:Phosphates / Q000502:physiology; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000502:physiology; D011494:Protein Kinases / Q000378:metabolism* / Q000502:physiology; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D004718:Saccharomycetales / Q000201:enzymology*; D013217:Starvation
D000596:Amino Acids; D018797:Cell Cycle Proteins; D018844:Cyclin-Dependent Kinases; D005656:Fungal Proteins; D005947:Glucose; D009584:Nitrogen; D028061:Phosphate Transport Proteins; D010710:Phosphates; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor); D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; D029701:Saccharomyces cerevisiae Proteins; C055831:phosphate permease; C116037:PAS domain kinases; C083324:TOR1 protein, S cerevisiae; C512912:GCN2 protein, S cerevisiae; C058605:PHO85 protein, S cerevisiae