[Damage of mitochondrial DNA in selected pathologies].
The presence of separate genetic information in the mitochondria let consider them as semiautonomous structures. Changes of mitochondrial genetic material were detected in many pathologies; they have a number of common traits, but they also differ in terms of frequency of occurrence. This paper presents data concerning mtDNA and a review of most commonly encountered mutations and the associated pathologies.
Latocha
Małgorzata T
MT
Slaskiej Akademii Medycznej, Katedry Biologii Molekularnej Biochemii i Biofarmacji w Sosnowcu.
Mazurek
Urszula M
UM
D004272:DNA, Mitochondrial; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D006801:Humans; D008928:Mitochondria / Q000235:genetics* / Q000378:metabolism; D009154:Mutation
D004272:DNA, Mitochondrial