title: Long-term citrate anticoagulation for high-flux haemodialysis in a patient with heparin-induced thrombocytopenia type II.
abstract: For the first time, long-term use of regional citrate anticoagulation for high-flux haemodialysis is reported in a patient with heparin-induced thrombocytopenia type II. A simple, flow-independent, citrate infusion protocol allowed efficient anticoagulation. Excellent solute removal, indicated by KT/V values of 1.52 to 1.98, was achieved. Electrolyte and acid-base balance as well as calcium homeostasis were well controlled over a period of 9 months.
authors.affiliation: Division of Nephrology and Dialysis, Department of Medicine III, University of Vienna.
authors.forename: Beate
authors.initials: B
authors.lastname: Unver
authors.forename: G
authors.initials: G
authors.lastname: Sunder-Plassmann
authors.forename: W H
authors.initials: WH
authors.lastname: Hörl
authors.forename: R
authors.initials: R
authors.lastname: Apsner
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D002951:Citrates / Q000627:therapeutic use*; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D006435:Renal Dialysis / Q000009:adverse effects*; D013921:Thrombocytopenia / Q000209:etiology* / Q000628:therapy; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D002951:Citrates; D006493:Heparin