title: Nitrate tolerance: a unifying hypothesis.
authors.affiliation: Division of Cardiology, Department of Medicine, Mount Sinai and University Health Network Hospitals, University of Toronto, Toronto, Canada.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Gori
authors.forename: John D
authors.initials: JD
authors.lastname: Parker
mesh_terms: D000818:Animals; D001711:Biotransformation / Q000502:physiology; D004361:Drug Tolerance / Q000502:physiology*; D004730:Endothelium, Vascular / Q000378:metabolism; D006801:Humans; D009566:Nitrates / Q000378:metabolism / Q000494:pharmacology*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D030421:Peroxynitrous Acid / Q000378:metabolism; D010953:Plasma Volume / Q000187:drug effects; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology; D013481:Superoxides / Q000378:metabolism
chemical_list: D009566:Nitrates; D013481:Superoxides; D030421:Peroxynitrous Acid; D019001:Nitric Oxide Synthase