Activity of disinfectants against Gram-negative bacilli isolated from patients undergoing lung transplantation for cystic fibrosis.
Lung transplant recipients with cystic fibrosis are frequently colonized with antibiotic-resistant bacteria. We evaluated the in vitro activity of 5 disinfectants frequently used in cardiac surgery against strains of Burkholderia cepacia and Pseudomonas aeruginosa isolated from patients undergoing sequential single lung transplantation. Our results suggest that the activity of Taurolin and Noxyflex is superior to conventional disinfectants.
Perry
John D
JD
Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK.
Riley
Gavin
G
Johnston
Susan
S
Dark
John H
JH
Gould
F Kate
FK
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D016956:Burkholderia cepacia / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology; D003550:Cystic Fibrosis / Q000601:surgery*; D004202:Disinfectants / Q000494:pharmacology*; D006801:Humans; D016040:Lung Transplantation; D009677:Noxythiolin / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013654:Taurine / Q000031:analogs & derivatives* / Q000494:pharmacology; D013829:Thiadiazines / Q000494:pharmacology; D014260:Triclosan / Q000494:pharmacology
D000891:Anti-Infective Agents, Local; D004202:Disinfectants; D013829:Thiadiazines; D013654:Taurine; D009677:Noxythiolin; D014260:Triclosan; C012566:taurolidine; D002710:Chlorhexidine