Restrictive left ventricular filling pattern with preserved systolic function assessed by Doppler echocardiography: clinical, echocardiographic and prognostic implications.
From an echocardiographic laboratory database, echocardiographic characteristics of clinical and cardiovascular mortality were compared in patients with restrictive pattern of left ventricular filling (RPLVF) and left ventricular ejection fraction (LVEF) >50% (n = 36), with patients with RPLVF and LVEF <50% (n = 120) and echocardiographic controls (n = 160). Preserved LVEF was found in 21% of the patients with RPLVF. Mortality in patients with RPLVF was worst compared with echocardiographic controls regardless of their underlying LVEF after 2.7 +/- 1 years of follow-up. Patients with RPLVF had distinctive predictors of cardiovascular death, with clinical and echocardiographic characteristics according to their LVEF.
Boccalandro
Fernando
F
Division of Cardiology, University of Texas Houston Medical School, and Memorial-Hermann Hospital, Houston, Tex 77030, USA. Boccalandro@uth.tmc.edu
Loghin
Catalin
C
Darwood
Susan
S
Seung-Ho
Kang
K
Barasch
Eddy
E
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis* / Q000401:mortality / Q000503:physiopathology; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D016016:Proportional Hazards Models; D013318:Stroke Volume / Q000502:physiology; D016019:Survival Analysis; D013599:Systole / Q000502:physiology; D013781:Texas / Q000453:epidemiology; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000401:mortality / Q000503:physiopathology