Handedness and corpus callosum morphology.
Investigations of a relationship between callosal size and functional behavioral lateralization lead to the hypothesis that, as the size of the corpus callosum (CC) increases, interhemispheric information transfer is facilitated and behavioral laterality effects become smaller. The aim of our in vivo study was to investigate the relationship between functional asymmetry of handedness and CC size in healthy subjects. Magnetic resonance images of the CC and five CC subregions were obtained with a 1.5-T Magnetom using a three-dimensional T1 sequence in 46 healthy men. Handedness was determined using the 'handedness dominance test' (HDT). According to the HDT values, 32 consistent and 14 non-consistent right-handers were identified. No significant difference between handedness subgroups in CC regions and no significant correlations between HDT values and CC areas were detected.
Preuss
Ulrich W
UW
Department of Psychiatry, Ludwig-Maximilians-Universität München (LMU), Nussbaumstr. 7, D-80336 Munich, Germany.
Meisenzahl
Eva M
EM
Frodl
Thomas
T
Zetzsche
Thomas
T
Holder
Jan
J
Leinsinger
Gerda
G
Hegerl
Ulrich
U
Hahn
Klaus
K
Möller
Hans-Jürgen
HJ
D000293:Adolescent; D000328:Adult; D003337:Corpus Callosum / Q000033:anatomy & histology*; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012016:Reference Values