title: Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein.
authors.affiliation: Department of Biopharmaceutical Sciences, University of California San Francisco, USA.
authors.forename: Carolyn L
authors.initials: CL
authors.lastname: Cummins
authors.forename: Chi-Yuan
authors.initials: CY
authors.lastname: Wu
authors.forename: Leslie Z
authors.initials: LZ
authors.lastname: Benet
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000502:physiology*; D000818:Animals; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000502:physiology*; D004917:Erythromycin / Q000493:pharmacokinetics; D006801:Humans; D008657:Metabolic Clearance Rate; D008874:Midazolam / Q000493:pharmacokinetics; D012727:Sex Characteristics
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D004917:Erythromycin; D003577:Cytochrome P-450 Enzyme System; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; D008874:Midazolam