[Subacute thyroiditis with cell destruction and temporary hyperthyroidism in Graves'disease--case report].
We present the case of a 60-year old woman with painful swelling of the thyroid gland and temporary thyrotoxicosis. 30 years ago she had experienced a period of hyperthyroidism because of Graves' disease. This time thyrotropin-receptor-antibodies were negative, Tc-99 m scan revealed decreased uptake in both lobes (this pattern normalised later on) and fine needle aspiration presented leucocyte infiltration of the thyroid. Three months later hypothyroidism was observed requiring treatment with levothyroxine. The development of subacute thyroiditis and Graves' disease in the same person is rare, autoimmune factors and a possible relationship are discussed.
Pichler
R
R
Institut für Nuklearmedizin und Endokrinologie, Allgemeines Krankenhaus Linz, Krankenhausstrasse 9, A-4020 Linz. Robert.Pichler@akh.linz.at
Wölfl
Soraya
S
Bogner
St
S
Sulzbacher
H
H
Shamiyeh
A
A
Maschek
Wilhelmine
W
D001323:Autoantibodies / Q000097:blood; D005260:Female; D006111:Graves Disease / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D006980:Hyperthyroidism / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D007037:Hypothyroidism / Q000188:drug therapy / Q000209:etiology; D008875:Middle Aged; D011877:Radionuclide Imaging; D013966:Thyroiditis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use; D014284:Triiodothyronine / Q000097:blood
D001323:Autoantibodies; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine