title: [Central nervous system germinoma: retrospective study of six cases].
abstract: OBJECTIVE
  Retrospective analysis of six patients with intracranial germinoma treated in INO and a literature review.
  
  
  METHODS
  Six patients were treated from 1993 to 1998, for histologically verified primary intracranial germinoma. Median age was 18 years (range: 14-26 years). All patients received chemo-radiotherapy (4FP + radiotherapy from 30 to 50 Gy).
  
  
  RESULTS
  4 tumours were in complete remission. Two patients have kept non-evolutive residual cyst. Five patients are alive with non-evolutive disease after 15-40 months of follow-up (average: 27 months). One patient was lost to follow-up, 14 months after treatment, without disease.
  
  
  CONCLUSIONS
  The treatment of intracranial germinoma is currently first line chemotherapy followed by low-dose and limited irradiation.
authors.affiliation: Service de radiothérapie, Institut national d'oncologie, BP 6213 RI-Rabat, Maroc.
authors.forename: H
authors.initials: H
authors.lastname: Sifat
authors.forename: K
authors.initials: K
authors.lastname: Haddadi
authors.forename: E
authors.initials: E
authors.lastname: el Ghazi
authors.forename: H
authors.initials: H
authors.lastname: Errihani
authors.forename: M
authors.initials: M
authors.lastname: Kamouni
authors.forename: H
authors.initials: H
authors.lastname: Mansouri
authors.forename: K
authors.initials: K
authors.lastname: Hassouni
authors.forename: H
authors.initials: H
authors.lastname: Bakkali
authors.forename: L
authors.initials: L
authors.lastname: Kanouni
authors.forename: M
authors.initials: M
authors.lastname: Gaye
authors.forename: T
authors.initials: T
authors.lastname: Kebdani
authors.forename: N
authors.initials: N
authors.lastname: Benjaafar
authors.forename: B K
authors.initials: BK
authors.lastname: el Gueddar
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000532:radiotherapy*; D018572:Disease-Free Survival; D018237:Germinoma / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D013997:Time Factors