title: Dosimetry comparison of 192Ir sources.
abstract: 192Ir sources besides being widely utilized in the field of conventional brachytherapy also find use in contemporary peripheral and coronal intravascular applications. In this study, the same Monte Carlo simulation code and input data were used to investigate differences between the dose rate distributions of the most commonly used 192Ir sources in the cm and mm distance range. Findings are discussed in view of differences in source and encapsulation dimensions as well as structural details. Results are presented in the AAPM TG-43 formalism, as generalized by AAPM TG-60, for five 192Ir HDR source designs as well as an LDR seed and an LDR wire source. Dose rate constants of the sources at r0 = 1 cm and r0 = 2 mm were found proportional to the corresponding geometry factors along the transverse source bisectors and an equation of the form lambda r0(cGyh(-1) U(-1)) = 1.12 x G(r0,90 degrees) provides results within clinical accuracy (less than 2%) for any 192Ir source. Radial dose functions do not depend significantly on source and encapsulation geometry and agree within 2% with that of a point 192Ir source. Anisotropy is of importance for accurate dosimetry at the cm distance range but it does not affect dose rate in the mm distance range significantly. At such short radial distances the source geometry factor defines the shape of isodose lines. Dose uniformity at given distances from the sources is strongly dependent on source dimensions as indicated by dose rate profiles in polar and Cartesian coordinates.
authors.affiliation: Physics Department, University of Athens, Greece. ppapagi@cc.uoa.gr
authors.forename: P
authors.initials: P
authors.lastname: Papagiannis
authors.forename: A
authors.initials: A
authors.lastname: Angelopoulos
authors.forename: E
authors.initials: E
authors.lastname: Pantelis
authors.forename: L
authors.initials: L
authors.lastname: Sakelliou
authors.forename: D
authors.initials: D
authors.lastname: Baltas
authors.forename: P
authors.initials: P
authors.lastname: Karaiskos
authors.forename: P
authors.initials: P
authors.lastname: Sandilos
authors.forename: L
authors.initials: L
authors.lastname: Vlachos
mesh_terms: D016880:Anisotropy; D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods; D007496:Iridium Radioisotopes; D009010:Monte Carlo Method; D017785:Photons; D011874:Radiometry / Q000379:methods*
chemical_list: D007496:Iridium Radioisotopes