Effect of fibrinogen on functional activity of blood leukocytes.
Fibrinogen intensified luminol-dependent chemiluminescence of blood leukocytes stimulated with opsonized zymosan. It is hypothesized that fibrinogen stimulates and prolongs functional activity of leukocytes during inflammation.
Zhambalova
B A
BA
Laboratory of Biophysical Basis of Pathology, Institute of Physicochemical Medicine, Ministry of Health of the Russian Federation, Moscow. arsbaya@chat.ru
Azizova
O A
OA
Lopukhin
Yu M
YM
D004305:Dose-Response Relationship, Drug; D005340:Fibrinogen / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D007202:Indicators and Reagents / Q000494:pharmacology; D007249:Inflammation; D007962:Leukocytes / Q000187:drug effects / Q000378:metabolism*; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology; D013997:Time Factors; D015054:Zymosan / Q000494:pharmacology
D007202:Indicators and Reagents; D008165:Luminol; D005340:Fibrinogen; D015054:Zymosan