Molybdenum-mediated cleavage reactions of isoxazoline rings fused in bicyclic frameworks.
The molybdenum-mediated cleavage reactions of isoxazoline rings fused in bicyclic frameworks were investigated. A tandem N-O bond cleavage-retro aldol reaction of an isoxazoline ring fused in a bicyclic framework led to the cleavage of the bicyclic framework. These reactions provide a novel stereoselective synthesis of substituted cyclopentene rings, cyclopentane rings, and attached-ring systems. [reaction: see text]
Tranmer
Geoffrey K
GK
Guelph-Waterloo Centre for Graduate Work in Chemistry and Biochemistry, Department of Chemistry and Biochemistry, University of Guelph, Guelph, Ontario, Canada N1G 2W1.
Tam
William
W