title: [Optic disc pits and maculopathy (electroretinography study)].
abstract: An ERG examination according to the international standard was made in 55 patients with pits in the optic nerve disc. 19 of them suffered from concurrent maculopathy. Electroretinography revealed in scotopic responses a significant reduction of amplitudes of oscillatory potentials and reduction of potentials of the b wave in standard (maximal) reactions. Even more markedly the cone reactions and flicker were reduced--responses to intermittent (30 Hz) photostimulation. The authors consider maculopathies with pits a separate nosological unit with possible hereditary transmission. ERG signalizes a more extensive alteration of retinal structures than affection of the centre, probably on the basis of the circulation. Maculopathies with pits are also characterized by the fact that the dramatic drop of amplitudes is associated with the patient's age or the duration of the disease.
authors.affiliation: Ocní klinika Fakultní nemocnice, Hradec Králové. sverak@fnhk.cz
authors.forename: J
authors.initials: J
authors.lastname: Svĕrák
authors.forename: E
authors.initials: E
authors.lastname: Rencová
authors.forename: J
authors.initials: J
authors.lastname: Kvasnicka
authors.forename: J
authors.initials: J
authors.lastname: Peregrin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004596:Electroretinography; D005260:Female; D006801:Humans; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000002:abnormalities*; D012164:Retinal Diseases / Q000150:complications / Q000175:diagnosis*