Polyarteritis associated with hypopharyngeal carcinoma.
A rare case of polyarteritis associated with a solid tumor is presented. A 66-year-old man was referred to our hospital, because of gangrene in the bilateral fingers and toes, right pleural effusion, and an abnormal sensation in the throat. A diagnosis of polyarteritis was made based on pleuritis, digital gangrene and the arteriography findings. He also had a hypopharyngeal carcinoma. After being treated with intermittent intravenous cyclophosphamide, oral corticosteroid, alprostadil and aspirin, the pleural effusion rapidly disappeared, while the digital gangrene gradually improved. For the treatment of hypopharyngeal carcinoma, radiation therapy was initiated and resulted in complete disappearance.
Okada
Makoto
M
Internal Medicine I, National Defense Medical College, Tokorozawa, Saitama.
Suzuki
Kimihiro
K
Hidaka
Toshihiko
T
Shinohara
Tadashi
T
Takada
Kunio
K
Nakajima
Masahiro
M
Nakanishi
Takashi
T
Ohsuzu
Fumitaka
F
D000368:Aged; D000792:Angiography; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D010257:Paraneoplastic Syndromes / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D010996:Pleural Effusion / Q000209:etiology / Q000628:therapy; D010488:Polyarteritis Nodosa / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D013902:Radiography, Thoracic; D016896:Treatment Outcome
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D008775:Methylprednisolone