title: Revealing micro-RNAs in plants.
abstract: Recent work has resulted in the identification of >100 endogenous non-coding small RNA molecules in plants. These micro-RNAs (miRNAs) have the capacity to regulate a range of predicted target mRNAs, many of which are transcription factors involved in the control of meristem identity. Mutants defective in either CARPEL FACTORY or Hen1 fail to accumulate miRNAs and have severe developmental defects. Thus, miRNAs are implicated as potentially key regulatory molecules in plant development.
authors.affiliation: Dept of Biology, University of York, Heslington, YO10 5YW, UK. alj2@york.ac.uk
authors.forename: Louise
authors.initials: L
authors.lastname: Jones
mesh_terms: D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism; D003001:Cloning, Molecular; D004722:Endoribonucleases / Q000235:genetics / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism; D035683:MicroRNAs / Q000235:genetics*; D063245:Plant Development; D010944:Plants / Q000235:genetics*; D043244:Ribonuclease III; D014157:Transcription Factors
chemical_list: D029681:Arabidopsis Proteins; D018797:Cell Cycle Proteins; C450825:HEN1 protein, Arabidopsis; D018398:Homeodomain Proteins; D035683:MicroRNAs; C114647:PHB protein, Arabidopsis; C114644:PHV protein, Arabidopsis; D014157:Transcription Factors; D004722:Endoribonucleases; C402383:DCL1 protein, Arabidopsis; D043244:Ribonuclease III