Thromboprophylaxis with low molecular weight heparin in thrombophilia-complicated pregnancy.
We treated three thrombophilia-complicated pregnant women (two antiphospholipid antibody syndrome, one protein C deficiency) with low molecular weight heparin (dalteparin). All three pregnancies including one twin pregnancy ended in live births without a decrease in bone mineral density. This treatment modality was effective and safe preventing thrombosis during their pregnancies.
Ebina
Yasuhiko
Y
Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan. yasuhiko-ebina@hokkaido.med.or.jp
Yamada
Hideto
H
Kato
Emi H
EH
Yamamoto
Ritsu
R
Sakuragi
Noriaki
N
Fujimoto
Seiichiro
S
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000188:drug therapy; D017985:Dalteparin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000517:prevention & control*; D011256:Pregnancy Outcome; D020151:Protein C Deficiency / Q000188:drug therapy; D013923:Thromboembolism / Q000517:prevention & control*
D000925:Anticoagulants; D017985:Dalteparin