title: Mycoplasma hominis infection in heart and lung transplantation.
abstract: "Culture-negative" wound infection and mediastinitis secondary to Mycoplasma hominis have been reported after cardiothoracic surgery but no case cluster has ever been described. We report 4 cases of infection in 3 cardiac and 1 bilateral sequential lung transplant recipient over 3 weeks of hospitalization. Successful treatment was achieved with early aggressive surgical intervention and combination antibiotics of clindamycin, doxycycline and/or ciprofloxacin. This cluster raises the question of nosocomial transmission of infection and supports a recommendation for single-room isolation and universal precautions for infected individuals.
authors.affiliation: Heart-Lung Transplant Unit, St Vincent's Hospital, Darlinghurst, Sydney, Australia
authors.forename: Peter M
authors.initials: PM
authors.lastname: Hopkins
authors.forename: David S
authors.initials: DS
authors.lastname: Winlaw
authors.forename: Prashant N
authors.initials: PN
authors.lastname: Chhajed
authors.forename: John L
authors.initials: JL
authors.lastname: Harkness
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Horton
authors.forename: Anne M
authors.initials: AM
authors.lastname: Keogh
authors.forename: Monique A
authors.initials: MA
authors.lastname: Malouf
authors.forename: Allan R
authors.initials: AR
authors.lastname: Glanville
mesh_terms: D000293:Adolescent; D000328:Adult; D016000:Cluster Analysis; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D016027:Heart Transplantation; D006801:Humans; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000453:epidemiology*; D019535:Mycoplasma hominis; D013529:Surgical Wound Dehiscence / Q000453:epidemiology / Q000382:microbiology*