Triplet cervical pregnancy treated with intraamniotic methotrexate.
BACKGROUND
Multifetal cervical pregnancy is very rare. We are reporting a case of a triplet cervical pregnancy that was treated with direct intraamniotic instillation of methotrexate.


METHODS
A young multiparous woman was diagnosed as having three gestational sacs in her uterine cervix with embryonic cardiac activity observed within one of the sacs. She became pregnant by natural ovulation and coitus. After initial failure with a single-dose intramuscular injection, the patient was successfully treated with an intra-amniotic methotrexate injection under the guidance of transvaginal ultrasonography. Her reproductive capability was preserved.


CONCLUSIONS
Direct intraamniotic injection can be considered as treatment for multifetal cervical pregnancy.
Jeong
Eun-Hwan
EH
Department of Obstetrics and Gynecology, Chungbuk National University Hospital, Cheongju, South Korea. jeong@med.chungbuk.ac.kr
Kim
Yong-Beom
YB
Ji
Ill-Woon
IW
Kim
Hak Soon
HS
D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage*; D000650:Amnion; D002584:Cervix Uteri; D005260:Female; D006801:Humans; D007267:Injections; D008727:Methotrexate / Q000008:administration & dosage*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011271:Pregnancy, Ectopic / Q000188:drug therapy*; D011272:Pregnancy, Multiple; D014310:Triplets; D014463:Ultrasonography; D014621:Vagina / Q000000981:diagnostic imaging
D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate