title: [The effects of Cardiodoron on cardio-respiratory coordination--a literature review].
abstract: BACKGROUND
  In healthy subjects self-regulation of the organism establishes the order of rhythmical functions. This self-regulation is altered in patients suffering from idiopathic orthostatic syndrome resulting from disturbances of functional aspects only. Thus the cardio-respiratory coordination, which may serve as the representative of the order of rhythmical functions, is modified.
  
  
  OBJECTIVE
  In the case of idiopathic orthostatic syndrome the anthroposophic medicine offers the medicament Cardiodoron(r). Does it stimulate self-regulation in order to normalise the cardio-respiratory coordination?
  
  
  METHODS
  This claim is analysed by a systematic review of the literature. Only those publications were considered where the cardio-respiratory coordination was analysed in studies with patients or healthy subjects.
  
  
  RESULTS
  The methods of the studies with patients and healthy subjects vary strongly. Nevertheless, a normalisation of the cardio-respiratory coordination could be found in studies with patients suffering from idiopathic orthostatic syndrome as well as in studies with healthy subjects.
  
  
  CONCLUSIONS
  The studies show that the use of the medicament results in a normalisation of the cardiorespiratory coordination. By stimulating the self-regulation the medicament leads to an improvement of the order of rhythmical functions in the human organism.
authors.affiliation: Abteilung für Klinische Forschung, Gemeinschaftskrankenhaus Herdecke, Germany. dcysarz@rhythmen.de
authors.forename: D
authors.initials: D
authors.lastname: Cysarz
authors.forename: C
authors.initials: C
authors.lastname: Heckmann
authors.forename: H C
authors.initials: HC
authors.lastname: Kümmell
mesh_terms: D002940:Circadian Rhythm / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D012119:Respiration / Q000187:drug effects*; D016896:Treatment Outcome
chemical_list: C410806:Cardiodoron; D010936:Plant Extracts