title: Perforations and fistulae in gastrointestinal tuberculosis.
abstract: BACKGROUND
  Perforation and fistulae, though uncommon, are serious complications of gastrointestinal tuberculosis. Patients with acute tuberculous perforation are subjected to surgery, whereas localized perforation and fistulae with subtle clinical signs are detected by barium contrast examination. There has been no report on radiological series regarding the incidence of perforation and fistulae, detected by barium contrast studies.
  
  
  METHODS
  A retrospective analysis of barium contrast studies of 684 proven cases of gastrointestinal tuberculosis seen over a period of 15 years was done to detect the incidence of perforation and fistulae.
  
  
  RESULTS
  Fifty-two patients (7.6%) with localized perforation and fistulae were seen. Twenty-eight patients had evidence of perforation, and 24 patients showed fistulae formation. The most common site of perforation and fistulae was the small bowel followed by the colon. Associated abnormalities noted were ulcerations, strictures, nodular filling defects and extrinsic compression.
  
  
  CONCLUSIONS
  Perforation and fistulae along with other associated abnormalities of the gastrointestinal tract are suggestive of tuberculosis, particularly in a population predisposed to tuberculous infection.
authors.affiliation: Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: B
authors.initials: B
authors.lastname: Nagi
authors.forename: A
authors.initials: A
authors.lastname: Lal
authors.forename: R
authors.initials: R
authors.lastname: Kochhar
authors.forename: D K
authors.initials: DK
authors.lastname: Bhasin
authors.forename: B R
authors.initials: BR
authors.lastname: Thapa
authors.forename: K
authors.initials: K
authors.lastname: Singh
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D016154:Digestive System Fistula / Q000209:etiology*; D004939:Esophageal Perforation / Q000209:etiology; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D013275:Stomach Rupture / Q000209:etiology; D014385:Tuberculosis, Gastrointestinal / Q000150:complications*