title: Phosphorus metabolite changes in temporal lobes of subjects with schizotypal personality disorder.
abstract: Using in vivo (31)P magnetic resonance spectroscopy, phosphorus metabolite levels were measured in the temporal lobes of 11 neuroleptic-free subjects with schizotypal personality disorder (SPD) and 20 age-matched healthy subjects. SPD subjects showed smaller amounts of phosphomonoesters in the left temporal lobe than healthy subjects. Membrane phospholipid abnormalities in the left temporal lobe may be a common pathophysiologic feature in schizophrenia spectrum disorders.
authors.affiliation: Department of Neuropsychiatry, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, 890-8520, Kagoshima, Japan. fukuzako@m2.kufm.kagoshima-u.ac.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukuzako
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kodama
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Fukuzako
mesh_terms: D000328:Adult; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D010758:Phosphorus / Q000378:metabolism*; D012569:Schizotypal Personality Disorder / Q000378:metabolism*; D013702:Temporal Lobe / Q000378:metabolism*
chemical_list: D010758:Phosphorus