title: [Lessons learned from 274 laparoscopic adrenalectomies].
abstract: OBJECTIVE
  To define the role of minimally invasive video-assisted surgery in the surgical management of adrenal disease and discuss the respective indications of the trans and retroperitoneal video assisted approaches.
  
  
  METHODS
  During the last 8 years (1994-2001), 330 adrenalectomies were performed in 305 patients: 274 (83%) laparoscopic approaches and 56 (17%) open approach. Open surgery was reserved for patients presenting with large or malignant tumours (29 cases), multiple and/or extraadrenal phaeochromocytomas (13 cases), previous intraabdominal intestinal surgery (10 cases), and in those requiring concomitant intraabdominal surgery (4 cases). Laparoscopic adrenalectomy was performed using the lateral transperitoneal approach for 89 Conn's syndrome, 67 Cushing's syndrome, 2 virilizing tumours, 51 phaeochromocytomas and 65 non secretory tumours greater than 4 cm in diameter. Nineteen patients underwent bilateral adrenalectomy.
  
  
  RESULTS
  There were no deaths. Twenty patients (7.3%) had a complication. Eleven cases required open conversion (4%) because of difficulties with dissection (8 cases), preoperative suspicion of malignancy (2 cases), and one pneumothorax. The average size of tumours was 34 mm (7-110 mm). There were 18 malignant tumours (6.5%): 8 adrenocortical carcinomas, 1 leiomyosarcoma, and 9 metastases. All patients with hormonally secreting tumours were cured of their endocrinopathy. There was 1 death secondary to hepatic metastases in a patient with an adrenocortical carcinoma.
  
  
  CONCLUSIONS
  Most adrenal tumours are suitable for video assisted excision. The only absolute contraindication is an invasive carcinoma requiring an extended excision. The lateral, transperitoneal approach is the most suitable for tumours greater than 5-6 cm in diameter. Both the transperitoneal or retroperitoneal approaches are suitable for smaller tumours depending on operator choice and experience. However in the presence of a large right lobe of liver or previous intraabdominal surgery the retroperitoneal approach may be preferable.
authors.affiliation: Service de Chirurgie Générale et Endocrinienne, Hôpital de la Timone, boulevard Jean-Moulin, 13385, Marseille, France. jfhenry@ap-hm.fr
authors.forename: J F
authors.initials: JF
authors.lastname: Henry
authors.forename: F
authors.initials: F
authors.lastname: Sebag
authors.forename: M
authors.initials: M
authors.lastname: Iacobone
authors.forename: J
authors.initials: J
authors.lastname: Hubbard
authors.forename: S
authors.initials: S
authors.lastname: Maweja
mesh_terms: D000307:Adrenal Gland Diseases / Q000601:surgery; D000315:Adrenalectomy / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D000075202:Contraindications; D005602:France; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D007813:Laparotomy / Q000706:statistics & numerical data; D018579:Patient Selection; D011030:Pneumothorax / Q000209:etiology; D019106:Postoperative Hemorrhage / Q000209:etiology; D013923:Thromboembolism / Q000209:etiology; D016896:Treatment Outcome; D020535:Video-Assisted Surgery / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data