title: Dysphagia in Crohn's disease: a diagnostic challenge.
abstract: Dysphagia is a rare manifestation in a patient with Crohn's disease. We report on the case of a patient with long-standing Crohn's disease who developed progressive dysphagia over 3 years. Endoscopy showed minimal distal oesophagitis with non-specific histological findings. Further investigation with cinematography, barium swallow and manometry established an achalasia-like motility disorder. Biopsies obtained from the oesophagus were non-specific. Balloon dilatation was performed. Initial success was followed by recurrent dysphagia. At repeat endoscopy, an oesophageal fistula was detected. An attempt at conservative medical management failed and oesophagectomy was successfully performed. Pathology results of the resected specimen confirmed the suspected diagnosis of oesophageal Crohn's disease. Even if achalasia is suspected in a Crohn's patient, it should be taken into consideration that the motility disorder could be the result of a transmural inflammation with or without fibrosis caused by Crohn's disease.
authors.affiliation: Gl-Unit, Inselspital, University of Berne, Switzerland. christoph.knoblauch@spital-stans.ch
authors.forename: C
authors.initials: C
authors.lastname: Knoblauch
authors.forename: P
authors.initials: P
authors.lastname: Netzer
authors.forename: U
authors.initials: U
authors.lastname: Scheurer
authors.forename: F
authors.initials: F
authors.lastname: Seibold
mesh_terms: D000368:Aged; D002404:Catheterization; D003424:Crohn Disease / Q000150:complications* / Q000503:physiopathology; D003680:Deglutition Disorders / Q000209:etiology*; D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D004931:Esophageal Achalasia / Q000175:diagnosis / Q000209:etiology*; D004937:Esophageal Fistula / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D016629:Esophagectomy; D004941:Esophagitis / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D008365:Manometry