Recombinant single-chain and disulfide-stabilized Fv immunotoxins for cancer therapy.
Niv
Revital
R
Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel.
Segal
Dina
D
Reiter
Yoram
Y
D000818:Animals; D004220:Disulfides / Q000737:chemistry*; D015195:Drug Design; D005818:Genetic Engineering / Q000379:methods*; D006801:Humans; D007128:Immunoglobulin Fragments / Q000737:chemistry / Q000276:immunology; D007135:Immunoglobulin Variable Region / Q000737:chemistry / Q000276:immunology; D000922:Immunotoxins / Q000737:chemistry / Q000627:therapeutic use*; D051379:Mice; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D010957:Plasmids; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000302:isolation & purification* / Q000494:pharmacology* / Q000627:therapeutic use
D004220:Disulfides; D007128:Immunoglobulin Fragments; D007135:Immunoglobulin Variable Region; D000922:Immunotoxins; D011994:Recombinant Proteins; C055966:immunoglobulin Fv