Kinetic evidence for covalent phosphoryl-enzyme intermediate in phosphotransferase activity of human red cell pyrimidine nucleotidases.
Amici
Adolfo
A
Institute of Biochemistry, University of Ancona, 60100 Ancona, Italy.
Emanuelli
Monica
M
Ruggieri
Silverio
S
Raffaelli
Nadia
N
Magni
Giulio
G
D015720:5'-Nucleotidase / Q000378:metabolism*; D000818:Animals; D000970:Antineoplastic Agents / Q000378:metabolism; D000998:Antiviral Agents / Q000378:metabolism; D002384:Catalysis; D003561:Cytarabine / Q000378:metabolism; D004912:Erythrocytes / Q000201:enzymology*; D006801:Humans; D010770:Phosphotransferases / Q000378:metabolism*; D011742:Pyrimidine Nucleotides / Q000737:chemistry / Q000378:metabolism*; D051381:Rats; D013379:Substrate Specificity; D014867:Water / Q000378:metabolism; D015215:Zidovudine / Q000378:metabolism
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D011742:Pyrimidine Nucleotides; D003561:Cytarabine; D014867:Water; D015215:Zidovudine; D010770:Phosphotransferases; D015720:5'-Nucleotidase