title: Long-term outcome of patients with claudication after balloon angioplasty of the femoropopliteal arteries.
abstract: OBJECTIVE
  To report the long-term outcome of patients with lifestyle-limiting claudication after percutaneous transluminal angioplasty (PTA) of the femoropopliteal arteries.
  
  
  METHODS
  Between 1989 and 1992, 173 consecutive claudicant patients (mean age, 65 years; age range, 41-90 years) underwent PTA in 218 limbs; all interventions included femoral and/or popliteal arterial segments, and additional iliac (n = 27) and infrapopliteal (n = 11) arterial lesions were also treated. Patients were followed up for 7-10 years. Altogether, 37 (17%) limbs were classified as Fontaine class 2A, and 181 (83%) were class 2B. Average length of the primary lesion was 5.2 cm. Reinterventions were analyzed. Patency rates and patient survival were assessed by means of life table analysis. Cox-Mantel tests and Cox proportional hazards models were used to define associated independent determinants. Development of chronic critical ischemia (CCI) and its determinants was assessed by using the Pearson chi(2) test and multiple logistic regression analysis.
  
  
  RESULTS
  The primary and secondary patencies (+/- standard error of the estimate), respectively, were 46% +/- 3 and 63% +/- 3 at 1 year, 25% +/- 3 and 41% +/- 4 at 5 years, and 14% +/- 3 and 22% +/- 4 at 10 years. One-third (71 of 218) of the limbs required repeat interventions, including surgical revascularization in 35 limbs. Fourteen (6.4%) limbs developed CCI, resulting in a 0.8% incidence per year. In multivariate analysis, poor postinterventional peripheral runoff was an indicator of increased risk of CCI development (P =.03).
  
  
  CONCLUSIONS
  Although the long-term patency rates of PTA of the femoropopliteal arteries in claudicant patients were poor, the acceptable number of reinterventions and the low frequency of development of CCI imply the long-term benefits achievable with this treatment.
authors.affiliation: Department of Clinical Radiology, Kuopio University Hospital, Puijonlaaksontie 2, 70200 Kuopio, Finland. tiia.jamsen@kuh.fi
authors.forename: Tiia S
authors.initials: TS
authors.lastname: Jämsén
authors.forename: Hannu I
authors.initials: HI
authors.lastname: Manninen
authors.forename: Pekka A
authors.initials: PA
authors.lastname: Jaakkola
authors.forename: Pekka J
authors.initials: PJ
authors.lastname: Matsi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D003952:Diagnostic Imaging; D005260:Female; D005263:Femoral Artery; D005500:Follow-Up Studies; D006801:Humans; D007383:Intermittent Claudication / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D007511:Ischemia / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery; D011446:Prospective Studies; D012008:Recurrence; D019233:Retreatment; D015996:Survival Rate