Mycoplasma hominis infection in heart and lung transplantation.
"Culture-negative" wound infection and mediastinitis secondary to Mycoplasma hominis have been reported after cardiothoracic surgery but no case cluster has ever been described. We report 4 cases of infection in 3 cardiac and 1 bilateral sequential lung transplant recipient over 3 weeks of hospitalization. Successful treatment was achieved with early aggressive surgical intervention and combination antibiotics of clindamycin, doxycycline and/or ciprofloxacin. This cluster raises the question of nosocomial transmission of infection and supports a recommendation for single-room isolation and universal precautions for infected individuals.
Hopkins
Peter M
PM
Heart-Lung Transplant Unit, St Vincent's Hospital, Darlinghurst, Sydney, Australia
Winlaw
David S
DS
Chhajed
Prashant N
PN
Harkness
John L
JL
Horton
Matthew D
MD
Keogh
Anne M
AM
Malouf
Monique A
MA
Glanville
Allan R
AR
D000293:Adolescent; D000328:Adult; D016000:Cluster Analysis; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D016027:Heart Transplantation; D006801:Humans; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000453:epidemiology*; D019535:Mycoplasma hominis; D013529:Surgical Wound Dehiscence / Q000453:epidemiology / Q000382:microbiology*