title: Quantitative Doppler evaluation of the splenoportal venous system in various stages of cirrhosis: differences between right and left portal veins.
abstract: OBJECTIVE
  The purpose of our study was to evaluate the relationship between the splenoportal hemodynamics in patients with cirrhosis and the stage of the disease.
  
  
  METHODS
  Patients with cirrhosis were grouped according to modified Child-Pugh scoring into stages A, B, and C of cirrhosis. A control group of healthy volunteers was included. After gastroenterologic clinical and laboratory examinations, all participants underwent a splenoportal Doppler sonographic evaluation in which the vessels' diameter, area, and blood flow velocity were measured and blood flow rate and the congestion index in the splenoportal venous system were calculated.
  
  
  RESULTS
  Seventy-five patients with cirrhosis (25 women and 50 men) were enrolled; the control group consisted of 30 healthy volunteers (15 women and 15 men) with no liver disease. The mean age (+/- standard deviation) of the patients was 54.4 +/- 14.8 years (range, 13-80 years) and of the control subjects was 47.3 +/- 14.5 years (range, 18-72 years). No significant differences in vessel diameter, blood flow velocity, and blood flow rate were found in the main and left portal veins between the study group and the control group. In the right portal vein, we found decreases in the vessel diameter, blood flow velocity, and blood flow rate, and in the splenic vein, we found increases in vessel diameter and blood flow rate. The congestion index was increased in the main portal and splenic veins but was unchanged in the left portal vein.
  
  
  CONCLUSIONS
  Although our data indicate that there is no difference in Doppler sonographic parameters of the main portal vein according to Child-Pugh scores, the hemodynamic differences between the left and right branches of the portal vein may be clinically useful in patients with cirrhosis.
authors.affiliation: Department of Radiology, Turgut Ozal Medical Center, Inonu University School of Medicine, Elazig Yolu, Kampus, 44100 Malatya, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Kutlu
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Karaman
authors.forename: Ahmet
authors.initials: A
authors.lastname: Akbulut
authors.forename: Tamer
authors.initials: T
authors.lastname: Baysal
authors.forename: Ahmet
authors.initials: A
authors.lastname: Sigirci
authors.forename: Alpay
authors.initials: A
authors.lastname: Alkan
authors.forename: Murat
authors.initials: M
authors.lastname: Aladag
authors.forename: Yuksel
authors.initials: Y
authors.lastname: Seckin
authors.forename: Kaya
authors.initials: K
authors.lastname: Saraç
mesh_terms: D001783:Blood Flow Velocity; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011168:Portal System; D011169:Portal Vein / Q000000981:diagnostic imaging*; D018608:Ultrasonography, Doppler