Sensitization of trigeminal nociception specific for migraine but not pain of sinusitis.
Trigeminal pain processing was studied in 14 patients with unilateral migraine attacks and 14 age- and sex-matched patients with comparable unilateral headache from frontal sinusitis. Using a nociception-specific blink reflex method (nBR), a facilitation of nBR responses predominantly on the headache side was observed in migraine, but not in sinusitis. The facilitation of trigeminal nociception may be specific for migraine rather than a consequence of peripheral pain such as frontal sinusitis.
Katsarava
Z
Z
Department of Neurology, University of Essen, Germany. zaza.katsarava@uni-essen.de
Lehnerdt
G
G
Duda
B
B
Ellrich
J
J
Diener
H C
HC
Kaube
H
H
D000208:Acute Disease; D000328:Adult; D001767:Blinking; D005260:Female; D015522:Frontal Sinusitis / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology*; D009619:Nociceptors / Q000503:physiopathology*; D011930:Reaction Time; D014276:Trigeminal Nerve / Q000503:physiopathology*