Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics.
Rodríguez-Concepción
Manuel
M
Departament de Bioquímica i Biologia Molecular, Facultat de Química, Universitat de Barcelona, Martí i Franquès 1-7, 08028 Barcelona, Spain. mrodrigu@sun.bq.ub.es
Boronat
Albert
A
D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D001419:Bacteria / Q000235:genetics* / Q000378:metabolism; D019295:Computational Biology / Q000379:methods; D004896:Erythritol / Q000031:analogs & derivatives* / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005578:Fosfomycin / Q000031:analogs & derivatives* / Q000494:pharmacology; D023281:Genomics / Q000379:methods; D007211:Indoles / Q000378:metabolism; D018551:Solanum lycopersicum / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D008798:Mevalonic Acid / Q000378:metabolism; D008969:Molecular Sequence Data; D018087:Plastids / Q000235:genetics* / Q000378:metabolism; D011106:Polyisoprenyl Phosphates / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D017386:Sequence Homology, Amino Acid; D013403:Sugar Phosphates / Q000378:metabolism*
C114232:2-C-methylerythritol 4-phosphate; D007211:Indoles; D011106:Polyisoprenyl Phosphates; D013403:Sugar Phosphates; D005578:Fosfomycin; C041272:indolepropanol phosphate; C024640:fosmidomycin; D004896:Erythritol; D008798:Mevalonic Acid