Investigation of radiation-dose-induced changes in organic light-atom crystals by accurate d-spacing measurements.
Changes in d-spacing have been measured for organic compounds as a function of temperature, wavelength and primary beam intensity using intense synchrotron radiation. The d-spacings of organic and protein crystals were found to increase irreversibly as a function of radiation dose. The activation energy of this thermally activated process was estimated. No evidence for a significant temperature increase of the sample due to exposure to intense X-ray beams could be found experimentally for flux densities up to 4 x 10(12) photons s-1 mm-2.
Müller
Ralf
R
Institut für Kristallographie, RWTH-Aachen, Germany. ralf@deres-mueller.de
Weckert
Edgar
E
Zellner
Johannes
J
Drakopoulos
Michael
M
D003460:Crystallization; D004307:Dose-Response Relationship, Radiation; D006358:Hot Temperature; D006801:Humans; D018499:Linear Energy Transfer / Q000528:radiation effects*; D011506:Proteins / Q000528:radiation effects* / Q000648:ultrastructure*; D012542:Scattering, Radiation; D014961:X-Ray Diffraction
D011506:Proteins