Phase-vanishing reactions that use fluorous media as a phase screen. Facile, controlled bromination of alkenes by dibromine and dealkylation of aromatic ethers by boron tribromide.
In fluorous triphasic reactions, such as bromination of alkenes by dibromine and dealkylation of aromatic ethers by boron tribromide, the middle fluorous phase acts as a liquid membrane permitting passive transport of the reagents at the bottom to the top layer involving the substrates, thereby regulating the reactions.
Ryu
Ilhyong
I
Department of Chemistry, Faculty of Arts and Sciences, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan. ryu@ms.cias.osakafu-u.ac.jp
Matsubara
Hiroshi
H
Yasuda
Shinji
S
Nakamura
Hiroyuki
H
Curran
Dennis P
DP
D000475:Alkenes / Q000737:chemistry*; D000478:Alkylation; D001896:Boron Compounds / Q000737:chemistry*; D001966:Bromine / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry*; D005466:Fluorocarbons / Q000737:chemistry*; D006842:Hydrocarbons, Brominated / Q000138:chemical synthesis*
D000475:Alkenes; D001896:Boron Compounds; D004987:Ethers; D005466:Fluorocarbons; D006842:Hydrocarbons, Brominated; C078626:perflexane; D001966:Bromine