[Chloroquine cardiomyopathy revealed by complete atrio-ventricular block. A case report].
We describe a rare case of chloroquine cardiomyopathy occurring during long term (7 years) treatment for rheumatoid polyarthritis in a 42 year old woman. There was an isolated acute severe conduction defect, which is particularly rare. Histological study with the electron microscope allowed confirmation of this diagnosis. We report here the secondary cardiological effects of this frequently used synthetic antimalarial.
Charlier
P
P
Service de cardiologie, hôpital Lariboisière.
Cochand-Priollet
B
B
Polivka
M
M
Goldgran-Tolédano
D
D
Leenhardt
A
A
D000208:Acute Disease; D000328:Adult; D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000473:pathology; D002738:Chloroquine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006327:Heart Block / Q000139:chemically induced* / Q000150:complications; D006801:Humans; D008854:Microscopy, Electron
D018501:Antirheumatic Agents; D002738:Chloroquine