GeneCards 2002: towards a complete, object-oriented, human gene compendium.
BACKGROUND
In the post-genomic era, functional analysis of genes requires a sophisticated interdisciplinary arsenal. Comprehensive resources are challenged to provide consistently improving, state-of-the-art tools.


RESULTS
GeneCards (Rebhan et al., 1998) has made innovative strides: (a). regular updates and enhancements incorporating new genes enriched with sequences, genomic locations, cDNA assemblies, orthologies, medical information, 3D protein structures, gene expression, and focused SNP summaries; (b). restructured software using object-oriented Perl, migration to schema-driven XML, and (c). pilot studies, introducing methods to produce cards for novel and predicted genes.
Safran
Marilyn
M
Departments of Molecular Genetics Biological Services (Bioinformatics Unit) Molecular Cell Biology, The Weizmann Institute of Science, Rehovot, Israel. marilyn.safran@weizmann.ac.il
Solomon
Irina
I
Shmueli
Orit
O
Lapidot
Michal
M
Shen-Orr
Shai
S
Adato
Avital
A
Ben-Dor
Uri
U
Esterman
Nir
N
Rosen
Naomi
N
Peter
Inga
I
Olender
Tsviya
T
Chalifa-Caspi
Vered
V
Lancet
Doron
D
D000465:Algorithms; D002874:Chromosome Mapping / Q000379:methods; D003195:Computer Communication Networks; D003628:Database Management Systems; D030541:Databases, Genetic; D020869:Gene Expression Profiling / Q000379:methods; D015894:Genome, Human; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D016415:Sequence Alignment / Q000379:methods; D017421:Sequence Analysis / Q000379:methods