[Long-term ambulatory follow-up of hypertension patients with low renin activity in blood].
OBJECTIVE
To characterize a clinical course of arterial hypertension in patients with low activity of blood renin.


METHODS
44 hypertensive patients with low activity of blood renin participated in the trial. They were divided into three groups consisting of 18, 14 and 12 patients (group 1, 2 and 3 with adrenal adenoma, adrenal hyperplasia and hypertension, respectively).


RESULTS
Baseline hypertension was higher in group 1. The clinical picture did not differ much between the groups. Long-term follow-up has revealed that mean arterial pressure tended to lowering in groups 1 and 2 while in group 3 it tended to rise. Incidence of arrhythmia increased thrice though myasthenia became less frequent.


CONCLUSIONS
Group 1 patients had a more severe clinical course of hypertension with high lethality and many associated diseases. To achieve a clinical effect, they had to take higher doses of antihypertensive drugs.
Iurenev
A P
AP
Patrusheva
I F
IF
D000553:Ambulatory Care; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology*; D008991:Monitoring, Physiologic / Q000379:methods*; D012083:Renin / Q000097:blood*
D012083:Renin