title: Stevens-Johnson syndrome: case presentation.
abstract: Erythema Multiforme (EM) is a rare mucocutaneous disease with a variety of clinical manifestations. EM it was recognized in the early 1800's, and still the etiology is unknown. It has been recently suggested erythema multiforme (EM) major and Stevens-Johnson Syndrome (SJS) could be separated as two distinct clinical disorders with similar mucosal erosions, but different patterns of cutaneous lesions. In particular SJS should be used for a syndrome characterized by mucous membrane erosions and widespread small blisters that appear on erythematous or purpuric maculae, which are different from classic targets. In SJS mouth, eyes, skin, genitalia and occasionally the esophagus and respiratory track may be affected. Oral lesions may cause severe pain and usually lips may become encrusted. Concerning ocular involvement, if there is conjunctivitis or uveitis this may lead to scarring and blindness. Also, the course of disease and the prognosis are in most cases severe.
authors.affiliation: Department of Oral Diagnosis and Radiology, University of Athens Dental School, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Donta-Bakoyianni
authors.forename: A G
authors.initials: AG
authors.lastname: Mitsea
authors.forename: K
authors.initials: K
authors.lastname: Deodoropoulou-Papadimitriou
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002981:Clindamycin / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008046:Lip / Q000473:pathology; D008297:Male; D008776:Methylprednisolone Hemisuccinate / Q000627:therapeutic use; D019226:Oral Ulcer / Q000209:etiology*; D013262:Stevens-Johnson Syndrome / Q000145:classification / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D009626:Terminology as Topic
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D002981:Clindamycin; D008776:Methylprednisolone Hemisuccinate