title: Handedness and corpus callosum morphology.
abstract: Investigations of a relationship between callosal size and functional behavioral lateralization lead to the hypothesis that, as the size of the corpus callosum (CC) increases, interhemispheric information transfer is facilitated and behavioral laterality effects become smaller. The aim of our in vivo study was to investigate the relationship between functional asymmetry of handedness and CC size in healthy subjects. Magnetic resonance images of the CC and five CC subregions were obtained with a 1.5-T Magnetom using a three-dimensional T1 sequence in 46 healthy men. Handedness was determined using the 'handedness dominance test' (HDT). According to the HDT values, 32 consistent and 14 non-consistent right-handers were identified. No significant difference between handedness subgroups in CC regions and no significant correlations between HDT values and CC areas were detected.
authors.affiliation: Department of Psychiatry, Ludwig-Maximilians-Universität München (LMU), Nussbaumstr. 7, D-80336 Munich, Germany.
authors.forename: Ulrich W
authors.initials: UW
authors.lastname: Preuss
authors.forename: Eva M
authors.initials: EM
authors.lastname: Meisenzahl
authors.forename: Thomas
authors.initials: T
authors.lastname: Frodl
authors.forename: Thomas
authors.initials: T
authors.lastname: Zetzsche
authors.forename: Jan
authors.initials: J
authors.lastname: Holder
authors.forename: Gerda
authors.initials: G
authors.lastname: Leinsinger
authors.forename: Ulrich
authors.initials: U
authors.lastname: Hegerl
authors.forename: Klaus
authors.initials: K
authors.lastname: Hahn
authors.forename: Hans-Jürgen
authors.initials: HJ
authors.lastname: Möller
mesh_terms: D000293:Adolescent; D000328:Adult; D003337:Corpus Callosum / Q000033:anatomy & histology*; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012016:Reference Values