title: Incidence of selective IgG2 deficiency in patients with vasculitis.
abstract: IgG2 deficiency has been recently associated with the appearance of vasculitis. None of the 42 patients with IgG2 deficiency whom we studied has a history of vasculitis. We have also studied 56 patients with vasculitis, and found four of them with IgG2 levels below the normal range for their age. As a group, the vasculitis patients did not differ in the incidence of low IgG2 levels from a normal population. Three of the four vasculitis patients with low IgG2 levels had a Henoch-Schonlein syndrome, and the association between both features was statistically significant.
authors.affiliation: Servicio de Immunologia, Hospital La Paz, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Jiménez
authors.forename: M
authors.initials: M
authors.lastname: López-Trascasa
authors.forename: G
authors.initials: G
authors.lastname: Fontán
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood; D002675:Child, Preschool; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications / Q000276:immunology; D017099:IgG Deficiency / Q000150:complications* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D014657:Vasculitis / Q000150:complications* / Q000276:immunology*
chemical_list: D001323:Autoantibodies