Catalytic enantioselective intermolecular [2 + 2 + 2] cycloaddition of an alkene and two alkynes.
A catalytic enantioselective intermolecular [2 + 2 + 2] cycloaddition of one molecule of alkene (enone) and two molecules of alkyne was developed in the presence of a nickel complex modified by chiral monodentate oxazoline ligands, which have not previously been used as chiral ligands for transition metals in asymmetric catalysts, and an aluminium phenoxide.
Ikeda
Shin-ichi
S
Graduate School of Pharmaceutical Sciences, Nagoya City University, Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan. ikeshin@phar.nagoya-cu.ac.jp
Kondo
Hirokazu
H
Arii
Taro
T
Odashima
Kazunori
K