Towards evidence based emergency medicine: best BETs from Manchester Royal Infirmary. Factor VIIa for intractable blood loss in trauma.
A short cut review was carried out to establish whether factor VIIa is indicated in patients suffering intractable blood loss after trauma. Altogether 59 papers were found using the reported search, of which two presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these best papers are tabulated. A clinical bottom line is stated.
Argall
Jon
J
Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Teece
Stewart
S
D015942:Factor VIIa / Q000627:therapeutic use*; D006470:Hemorrhage / Q000517:prevention & control*; D006801:Humans; D014947:Wounds and Injuries / Q000150:complications*
D015942:Factor VIIa