title: Contrast study on cognitive function with MRI and positron emission tomography imaging in transient global amnesia.
abstract: OBJECTIVE
  To study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA).
  
  
  METHODS
  Three patients with TGA were given mini-mental state examination (MMSE), revised Wechsler memory scale (WMS-R) examination and magnetic resonance imaging (MRI) scans after they had been diagnosed as TGA. Using (18)F labelled deoxyglucose as tracer, patients were given a positron emission tomography (PET) examination at different periods during recovery.
  
  
  RESULTS
  No obvious abnormality was found in MMSE and MRI scans in the three patients. However, WMS-R examination and cerebral PET imaging displayed cognitive dysfunction of varying degrees and low metabolism in local areas related to memory in 2 of 3 patients.
  
  
  CONCLUSIONS
  In TGA patients, cognitive function and cerebral metabolic levels are closely correlated with duration of symptoms. It is necessary to stop the TGA attack as quickly as possible early time.
authors.affiliation: Department of Neurology, General Hospital of Chinese PLA, Beijing 100853, China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Jia
authors.forename: Luning
authors.initials: L
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Yin
authors.forename: Hongchuan
authors.initials: H
authors.lastname: Tang
mesh_terms: D000368:Aged; D020236:Amnesia, Transient Global / Q000000981:diagnostic imaging / Q000523:psychology*; D003071:Cognition; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014055:Tomography, Emission-Computed