title: Beneficial effects of botulinum toxin type a for patients with painful tic convulsif.
abstract: Botulinum toxin is a well-known therapy for patients with diverse movement disorders. Its application has been extended to other disorders. Here, we document the case of a 70-year-old man with hemifacial spasm associated to trigeminal neuralgia secondary to an ectatic basilar artery. He was treated with botulinum toxin type A, 2.5 mouse units over five sites at the orbicularis oculi and one over the buccinator muscle. After botulinum toxin injections, relief was gained not only from twitching but also from pain. When the effects of the toxin vanished, spasms and pain recurred. Further infiltrations were given every 12 weeks following the same response pattern. This observation further validates the increasing role of botulinum toxin in pain management.
authors.affiliation: Programa de Parkinson y Movimientos Anormales, Instituto de Neurociencias, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina. Fmicheli@fibertel.com.ar
authors.forename: Federico
authors.initials: F
authors.lastname: Micheli
authors.forename: María Clara
authors.initials: MC
authors.lastname: Scorticati
authors.forename: Gabriela
authors.initials: G
authors.lastname: Raina
mesh_terms: D000368:Aged; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D019569:Hemifacial Spasm / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy; D013981:Tic Disorders / Q000188:drug therapy*; D016896:Treatment Outcome; D014277:Trigeminal Neuralgia / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A