title: Efficacy of the anesthetic protection in one-stage anterior and posterior spinal fusion in surgery of scoliosis.
abstract: Contemporary one-stage surgery of scoliosis including consecutive anterior and posterior spinal fusion is a highly traumatic procedure that requires effective anesthetic protection of the patient during operation and in the postoperative period. It has been established that anesthetic protection with alpha-1-adrenoblockers and alpha-2-adrenoantagonists of clofelin allows minimization of the postaggressive catabolic reactions of the organism, preventing severe impairment of homeostasis, reducing considerably the rate of intra- and postoperative complications and thus ensuring the favorable outcome of the operation. The proposed method of anesthetic protection by using propofol could be a method of choice when intraoperative awakening of the patient is needed to control for possible neurological deficit.
authors.affiliation: Novosibirsk Research Institute of Traumatology and Orthopaedics, Novosibirsk, Russia.
authors.forename: M N
authors.initials: MN
authors.lastname: Lebedeva
authors.forename: I P
authors.initials: IP
authors.lastname: Vereshtagin
authors.forename: V P
authors.initials: VP
authors.lastname: Shevchenko
authors.forename: E V
authors.initials: EV
authors.lastname: Bikova
authors.forename: M B
authors.initials: MB
authors.lastname: Mihaylovskii
authors.forename: V V
authors.initials: VV
authors.lastname: Novikov
mesh_terms: D000293:Adolescent; D000758:Anesthesia / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000627:therapeutic use; D002648:Child; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D015742:Propofol / Q000627:therapeutic use; D012600:Scoliosis / Q000601:surgery*; D013123:Spinal Fusion / Q000009:adverse effects / Q000379:methods*; D013312:Stress, Physiological / Q000209:etiology / Q000517:prevention & control
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol