title: Clinical and biochemical observations during treatment of depression with electroacupuncture: a pilot study.
abstract: Six patients suffering from major depression were treated with electroacupuncture. During 4 weeks of treatment, the total CPRS-S-A score decreased from 23.8 to 13.4 (p=0.0095). A decrease of neuropeptide Y (NPY) in plasma during the first 2 weeks of treatment was noted in five of the patients, all being women (p=0.0431). The decrease was negatively correlated with age (rs=-0.29; p=0.046). The results are in line with a putative antidepressive effect of electroacupuncture, along with an influence on NPY in plasma.
authors.affiliation: Department of Neuroscience and Locomotion, Division of Psychiatry, University Hospital, S-581 85 Linköping, Sweden. annika.pohl@lio.se
authors.forename: Annika
authors.initials: A
authors.lastname: Pohl
authors.forename: Conny
authors.initials: C
authors.lastname: Nordin
mesh_terms: D000368:Aged; D003866:Depressive Disorder / Q000378:metabolism / Q000523:psychology / Q000628:therapy*; D015671:Electroacupuncture; D004723:Endorphins / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009478:Neuropeptide Y / Q000097:blood; D009638:Norepinephrine / Q000097:blood; D010865:Pilot Projects; D011569:Psychiatric Status Rating Scales; D012701:Serotonin / Q000097:blood
chemical_list: D004723:Endorphins; D009478:Neuropeptide Y; D012701:Serotonin; D009638:Norepinephrine