title: Percutaneous microwave coagulation therapy for lung cancer.
abstract: OBJECTIVE
  To evaluate the clinical effect, CT image changes and side-effects of percutaneous microwave coagulation therapy for lung cancer.
  
  
  METHODS
  CT-guided percutaneous puncture was performed using a needle mono-pole microwave antenna with 65W, 2 450 MHz microwave delivered in 60 seconds to 20 peripheral lung cancer patients, including 8 suffering from primary lung cancer and 12 metastatic lung cancer (totally 28 lesions).
  
  
  RESULTS
  Sixteen patients were alive after having been followed-up for 3 approximately 24 months. All patients showed nodules decreased in size. Diminution of over 50% was observed in 13 nodules and 3, completely disappeared. The overall response rate was 57.1%. Ellipsoid shadow 3.5 cm x 2.5 cm across was observed by CT in lesions immediately after coagulation. Gasification within the coagulated area was observed in a week with a high density in the peripheral region. Consolidation was observed in 3 months and the lesion disappeared 1 year later. Complete tumor necrosis was proved by biopsy. No side-effects or complications were observed.
  
  
  CONCLUSIONS
  Percutaneous microwave coagulation therapy is a new safe treatment for lung cancer, giving marked effect but minimum trauma.
authors.affiliation: Department of Medical Oncology, Fourth Hospital, Hebei Medical University, Shijiazhuang 050011, China.
authors.forename: Weijian
authors.initials: W
authors.lastname: Feng
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Caiying
authors.initials: C
authors.lastname: Li
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Li
authors.forename: Ruxun
authors.initials: R
authors.lastname: Li
authors.forename: Fengling
authors.initials: F
authors.lastname: Liu
authors.forename: Baoe
authors.initials: B
authors.lastname: Zhai
authors.forename: Jian
authors.initials: J
authors.lastname: Shi
authors.forename: Gaofeng
authors.initials: G
authors.lastname: Shi
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D008872:Microwaves / Q000009:adverse effects / Q000627:therapeutic use*; D013534:Survival; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome