title: Analytical studies on two amino acid derivatives of anticonvulsant activity.
abstract: Qualitative and quantitative methods of analysis of two new amino acid derivatives, potential anticonvulsants of low neurotoxicity: N-acetyl-gamma-aminobutyric acid benzylamide (1) and N-melhyl-gamma-aminobutyric acid benzylamide (2) were developed. Qualitative analysis includes characteristic colour reactions, chromatographic (TLC) investigations, IR and UV spectra interpretation and quantitative analysis involves spectrophotometric, chromatographic (HPLC). acidimetric and argentomeric methods.
authors.affiliation: Department of Drug Chemistry, The Medical University of Warsaw, Poland.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Pirianowicz-Chaber
authors.forename: Ryszard
authors.initials: R
authors.lastname: Paruszewski
mesh_terms: D000596:Amino Acids / Q000032:analysis* / Q000737:chemistry; D000927:Anticonvulsants / Q000032:analysis* / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods / Q000706:statistics & numerical data; D005680:gamma-Aminobutyric Acid / Q000032:analysis / Q000737:chemistry
chemical_list: D000596:Amino Acids; D000927:Anticonvulsants; D005680:gamma-Aminobutyric Acid