title: [Assessment of peripheral blood perfusion during open heart surgery with sublingual PCO2 measured by ISFET-PCO2 sensor].
abstract: Sublingual tissue PCO2 (PSLCO2) was continuously monitored with an ISFET-based PCO2 sensor during and after the open-heart surgery under cardiopulmonary bypass (CPB) in order to study the effect of CPB on the peripheral blood perfusion. In addition, PSLCO2 monitoring was carried out in several cases of off-pump CABG. In the cases of open-heart surgery with CPB, PSLCO2 increased from 35.0 +/- 5.6 mmHg at the induction of anesthesia to the maximum value of 55.7 +/- 6.0 mmHg during CPB. After declamping of the aorta, PSLCO2 decreased gradually to 49.0 +/- 4.0 mm Hg 6 hr after the admission to ICU. The value of arterial lactate as another index of peripheral blood perfusion also increased gradually after the start of CPB, reaching to the maximum value of 8.8 +/- 1.1 mmol.l-1 just after being admitted into ICU. In the case of off-pump CABG, PSLCO2 and arterial lactate showed a slight increase during the later part of the surgery, but the change was not so significant as in the case of open-heart surgery under CPB. Through this study, typical changing pattern of PSLCO2 during the open-heart surgery was recognized. The change of PSLCO2 always preceded that of arterial lactate. We also experienced one case in which early stage of hypoperfusion was detected through the monitoring of PSLCO2. These results suggest clinical advantages of PSLCO2 monitoring.
authors.affiliation: Department of Anesthesiology, Koshigaya Hospital, Dokkyo University School of Medicine, Koshigaya 343-8555.
authors.forename: Hisashi
authors.initials: H
authors.lastname: Inoue
authors.forename: Misa
authors.initials: M
authors.lastname: Tsuchida
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Takano
authors.forename: Isao
authors.initials: I
authors.lastname: Sato
authors.forename: Yoji
authors.initials: Y
authors.lastname: Sato
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ikegami
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Sekiguchi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nagai
mesh_terms: D000328:Adult; D002245:Carbon Dioxide / Q000032:analysis*; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D010313:Partial Pressure; D010477:Perfusion; D013361:Sublingual Gland / Q000737:chemistry*
chemical_list: D002245:Carbon Dioxide; D019344:Lactic Acid