Global replacement of tryptophan with aminotryptophans generates non-invasive protein-based optical pH sensors.
Budisa
Nediljko
N
Max-Planck-Institut für Biochemie, Am Klopferspitz 18A, 82152, Martinsried, Germany. budisa@biochem.mpg.de
Rubini
Marina
M
Bae
Jae H
JH
Weyher
Elisabeth
E
Wenger
Waltraud
W
Golbik
Ralph
R
Huber
Robert
R
Moroder
Luis
L
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry; D001483:Base Sequence; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D005453:Fluorescence; D006863:Hydrogen-Ion Concentration; D008958:Models, Molecular; D055095:Optics and Photonics; D011487:Protein Conformation; D015202:Protein Engineering; D011506:Proteins / Q000138:chemical synthesis / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D014364:Tryptophan / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*
D001426:Bacterial Proteins; D011506:Proteins; C057438:barstar protein, Bacillus amyloliquefaciens; D014364:Tryptophan