Sequence of goat cyclin T1 cDNA, gene organisation and expression analysis.
The cyclin T1 (Cyc T1) protein has been recently identified, associated with the cyclin-dependent kinase 9 (CDK 9), as to be involved in the transcriptional activation of the Human Immunodeficiency Virus type 1 (HIV-1) by the Tat protein. In this study, the sequence of the 7 kb goat Cyc T1 cDNA is reported as well as the exon/intron structure of the gene. Its observed ubiquitous expression is consistent with the promoter structure.
Mata
Xavier
X
Laboratoire de Génétique Biochimique et de Cytogénétique, INRA, Jouy-en-Josas, France. mata@diamant.jouy.inra.fr
Taourit
Sead
S
Vilotte
Jean Luc
JL
D020413:3' Untranslated Regions; D020121:5' Untranslated Regions; D000818:Animals; D015152:Blotting, Northern; D003001:Cloning, Molecular; D017124:Conserved Sequence; D056906:Cyclin T; D016213:Cyclins / Q000096:biosynthesis / Q000235:genetics*; D018076:DNA, Complementary / Q000096:biosynthesis / Q000737:chemistry*; D005260:Female; D015870:Gene Expression; D015723:Gene Library; D006041:Goats; D007668:Kidney / Q000378:metabolism; D008297:Male; D008321:Mammary Glands, Animal / Q000378:metabolism; D018482:Muscle, Skeletal / Q000378:metabolism; D010053:Ovary / Q000378:metabolism; D016133:Polymerase Chain Reaction; D011401:Promoter Regions, Genetic; D013737:Testis / Q000378:metabolism
D020413:3' Untranslated Regions; D020121:5' Untranslated Regions; C503684:CCNT1 protein, human; D056906:Cyclin T; D016213:Cyclins; D018076:DNA, Complementary