title: Disturbances of saccadic eye movements in monkeys during development of MPTP-induced syndrome.
abstract: Changes in the amplitude and dynamic parameters of purposive saccades were studied in monkeys with MPTP-induced Parkinson-like syndrome. Lengthening of saccade latency, decreased maximum velocity of eye movements, and impaired saccade accuracy were observed at the early stages MPTP-syndrome. Different disturbances of large- and small-scale saccades were found.
authors.affiliation: Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov Moscow State University. lter@protein.bio.msu.ru
authors.forename: L V
authors.initials: LV
authors.lastname: Tereshchenko
authors.forename: A G
authors.initials: AG
authors.lastname: Yudin
authors.forename: YuB
authors.initials: Y
authors.lastname: Kuznetsov
authors.forename: A V
authors.initials: AV
authors.lastname: Latanov
authors.forename: V V
authors.initials: VV
authors.lastname: Shul'govskii
mesh_terms: D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine / Q000008:administration & dosage; D000818:Animals; D008251:Macaca; D020734:Parkinsonian Disorders; D011930:Reaction Time; D012438:Saccades / Q000502:physiology*
chemical_list: D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine