title: Management of gigantomastia complicating pregnancy. A case report.
abstract: BACKGROUND
  Gigantomastia during pregnancy is exceedingly rare, with an incidence of 1/28,000-100,000 pregnancies. Treatment during pregnancy is a dilemma, and postpartum reduction mammoplasty remains the mainstay of treatment.
  
  
  METHODS
  Massive bilateral breast enlargement occurred at 19 weeks of gestation in a 24-year-old woman, gravida 2, and led to ulceration and sloughing. Conservative management with bromocriptine resulted in healing of the ulcers and resolution of symptoms. After six months of bromocriptine therapy postpartum, marked involution of the breasts occurred without recurrence.
  
  
  CONCLUSIONS
  Prolonged bromocriptine therapy should be given after delivery to a pregnant woman with gigantomastia during pregnancy before planning surgical reduction mammoplasty.
authors.affiliation: Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India. nutan_agarwal@hotmail.com
authors.forename: Nutan
authors.initials: N
authors.lastname: Agarwal
authors.forename: Alka
authors.initials: A
authors.lastname: Kriplani
authors.forename: Anjali
authors.initials: A
authors.lastname: Gupta
authors.forename: Neerja
authors.initials: N
authors.lastname: Bhatla
mesh_terms: D000328:Adult; D001940:Breast / Q000473:pathology*; D001971:Bromocriptine / Q000627:therapeutic use*; D002585:Cesarean Section; D005260:Female; D006727:Hormone Antagonists / Q000627:therapeutic use*; D006801:Humans; D006984:Hypertrophy; D016462:Mammaplasty; D011181:Postnatal Care / Q000379:methods; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000473:pathology*; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods*; D011388:Prolactin / Q000037:antagonists & inhibitors*; D012883:Skin Ulcer / Q000209:etiology
chemical_list: D006727:Hormone Antagonists; D001971:Bromocriptine; D011388:Prolactin