Inactivation of tumor suppressor genes by promoter methylation is important in the pathogenesis of pancreatic cancer.
Fleming
Jason B
JB
Department of Surgery, Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390-8593, USA. Jason.Fleming@UTSouthwestern.edu
Minna
John D
JD
D000075982:Cell Adhesion Molecule-1; D015815:Cell Adhesion Molecules; D018899:CpG Islands / Q000235:genetics*; D019175:DNA Methylation; D015972:Gene Expression Regulation, Neoplastic; D020868:Gene Silencing; D016147:Genes, Tumor Suppressor; D006801:Humans; D007136:Immunoglobulins; D019656:Loss of Heterozygosity; D008565:Membrane Proteins; D010190:Pancreatic Neoplasms / Q000235:genetics* / Q000473:pathology; D011401:Promoter Regions, Genetic; D011506:Proteins / Q000235:genetics*; D025521:Tumor Suppressor Proteins
C403514:CADM1 protein, human; D000075982:Cell Adhesion Molecule-1; D015815:Cell Adhesion Molecules; D007136:Immunoglobulins; D008565:Membrane Proteins; D011506:Proteins; D025521:Tumor Suppressor Proteins