title: [Fibromatosis of the breast: clinical and pathology analysis of two cases].
abstract: Fibromatosis of the breast is an uncommon benign disease that mimics carcinoma clinically as well as radiographically. Its microscopic diagnosis among spindle cell tumors is fundamental, especially on frozen sections. We report two cases of mammary fibromatosis observed in young woman (26 and 31 years old). The two were clinically and mammographically suspect. Diagnosis was made on frozen sections and confirmed on paraffin embedded specimen. The lesions are characterized by spindle cell proliferation of variable cellularity and collagenization. Few mitotic figures were present in one case. Several lesions must be considered in the differential diagnosis of mammary fibromatosis. Wide local excision is recommended for initial therapy, but local recurrence is frequent. In our cases, In spite of apparently complete excision, one patient relapsed.
authors.affiliation: Service d'Anatomie et Cytologie Pathologiques, Institut Salah Azaiez, 1006 Bab Saadoun Tunis, Tunisie, France.
authors.forename: Maha
authors.initials: M
authors.lastname: Driss
authors.forename: Karima
authors.initials: K
authors.lastname: Mrad
authors.forename: Hedi
authors.initials: H
authors.lastname: Ben Amor
authors.forename: Imen
authors.initials: I
authors.lastname: Abbes
authors.forename: Samia
authors.initials: S
authors.lastname: Sassi
authors.forename: Khaled
authors.initials: K
authors.lastname: Ben Romdhane
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D003094:Collagen / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005629:Frozen Sections; D006801:Humans; D008327:Mammography; D008938:Mitosis; D009364:Neoplasm Recurrence, Local; D010232:Paraffin; D016610:Tissue Embedding
chemical_list: D010232:Paraffin; D003094:Collagen