title: Intralesional corticosteroid treatment of multiple eruptive keratoacanthomas: case report and review of a controversial therapy.
abstract: BACKGROUND
  Use of intralesional corticosteroids in the management of keratoacanthomas has been reported in older literature. Yet this therapy is no longer a commonly considered treatment option.
  
  
  OBJECTIVE
  To report management of a therapeutically challenging patient with multiple eruptive keratoacanthomas with intralesional corticosteriod treatment to revive awareness of this treatment option.
  
  
  METHODS
  A 55-year-old female with frequent episodes of multiple eruptive keratoacanthomas was treated with intralesional corticosteroids and methotrexate.
  
  
  RESULTS
  Intralesional corticosteroids successfully treated eruptive keratoacanthomas with complete regression and minimal scarring within 2-4 weeks.
  
  
  CONCLUSIONS
  Despite its limitations, intralesional corticosteroids may have a role in the treatment of select keratoacanthomas.
authors.affiliation: Dermatology Service and Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
authors.forename: Scott
authors.initials: S
authors.lastname: Sanders
authors.forename: Klaus J
authors.initials: KJ
authors.lastname: Busam
authors.forename: Allan C
authors.initials: AC
authors.lastname: Halpern
authors.forename: Kishwer S
authors.initials: KS
authors.lastname: Nehal
mesh_terms: D001132:Arm; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015552:Injections, Intralesional; D007636:Keratoacanthoma / Q000188:drug therapy*; D007866:Leg; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D014221:Triamcinolone / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D003879:Dermatologic Agents; D005938:Glucocorticoids; D014221:Triamcinolone; D008727:Methotrexate