Synthesis of a new water-soluble C(2)-symmetric chiral diamine: preliminary investigation of its catalytic properties for asymmetric hydrogenation under biphasic conditions.
A water-soluble version of N,N'-dimethyl-1,2-diphenylethane-1,2-diamine was prepared by introduction of phosphonic acid moieties on the para position of the aromatic rings. Preliminary investigation of the catalytic properties of the iridium complex of this ligand under biphasic conditions showed that this system compared well with the homogeneous counterpart for the asymmetric hydrogenation of ketones but with noticeably higher reaction rates for the biphasic system.
Maillet
Céline
C
Laboratoire de Synthèse Organique, UMR CNRS 6513, 2 Rue de la Houssinière, BP92208, 44322 Nantes Cedex 03, France.
Praveen
Thoniyot
T
Janvier
Pascal
P
Minguet
Sébastien
S
Evain
Michel
M
Saluzzo
Christine
C
Tommasino
M Lorraine
ML
Bujoli
Bruno
B