title: Molecular basis of inherited predispositions for tumors.
abstract: On the basis of literature data and own experience the authors review the current knowledge about the molecular basis of inherited predispositions for tumors. They hypothesize that in the near perspective 5-10 years studies using existing registry data/material and the latest novel technology will allow the identification of the molecular background for the majority of hereditary cancers which will have enormous practical consequences especially for the prevention of malignancies.
authors.affiliation: Department of Genetics and Pathology, Pomeranian Academy of Medicine, Szczecin, Poland.
authors.forename: Jan
authors.initials: J
authors.lastname: Lubiński
authors.forename: Bohdan
authors.initials: B
authors.lastname: Górski
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Kurzawski
authors.forename: Anna
authors.initials: A
authors.lastname: Jakubowska
authors.forename: Cezary
authors.initials: C
authors.lastname: Cybulski
authors.forename: Janina
authors.initials: J
authors.lastname: Suchy
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Debniak
authors.forename: Ewa
authors.initials: E
authors.lastname: Grabowska
authors.forename: Marcin
authors.initials: M
authors.lastname: Lener
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Nej
mesh_terms: D020137:Base Pair Mismatch / Q000235:genetics; D004252:DNA Mutational Analysis; D004260:DNA Repair / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D009154:Mutation / Q000235:genetics; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics*; D010375:Pedigree