title: Visceral nodular cartilaginous metaplasia in rockfishes (Sebastes spp.) in the eastern North Pacific Ocean.
abstract: Multiple, discrete, nodular foci of cartilaginous metaplasia were found in the spleens and kidneys of rockfishes taken from the northeastern Pacific Ocean during a survey to determine the incidence and the nature of diseases in these animals. These nodules sometimes occurred in association with granulomatous inflammation and distinct granulomas. Many of these fish were infected by Ichythophonus spp. or acid-fact bacteria (presumably Mycobacteria spp.). Some of the metaplastic foci contained encapsulated accumulations of eosinophilic vesicles and basophilic granular debris, described by other authors as "cysts of unknown etiology," which have been observed at different sites in a variety of temperate and tropical fish species.
authors.affiliation: Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University, Corvallis 97331-3804, USA.
authors.forename: Jerry R
authors.initials: JR
authors.lastname: Heidel
authors.forename: Barbara F
authors.initials: BF
authors.lastname: Nowak
authors.forename: Kay A
authors.initials: KA
authors.lastname: Fischer
authors.forename: Virginia G
authors.initials: VG
authors.lastname: Watral
authors.forename: Michael L
authors.initials: ML
authors.lastname: Kent
mesh_terms: D000818:Animals; D002357:Cartilage Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D003560:Cysts / Q000473:pathology / Q000662:veterinary; D005393:Fish Diseases / Q000382:microbiology*; D006099:Granuloma / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D008679:Metaplasia / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D009164:Mycobacterium Infections / Q000473:pathology / Q000662:veterinary; D010140:Pacific Ocean; D010473:Perciformes / Q000382:microbiology*