title: [The relationship between ostial patency and medical treatment in acute maxillary sinusitis: an experimental study].
abstract: OBJECTIVE
  We investigated the relationship between ostial patency and medical treatment in an experimental model of acute maxillary sinusitis.
  
  
  METHODS
  Forty healthy New Zealand white rabbits were assigned to two groups. The left maxillary sinus ostia were filled with absorbable gelatin sponge in one group (n=20). In the other group, half of the ostuim was blocked by bone particles and tissue adhesive (Histoacryl). Following induction of acute maxillary sinusitis, each group was divided into four subgroups, one of which was left untreated. The other subgroups received systemic antibiotic therapy plus topical administration of physiological saline solution, a decongestant, and a steroid, respectively, for 10 days. All rabbits were monitored for four weeks. Each week nasal smear samples were obtained for neutrophil and leucocyte counts. In the end, maxillary sinus biopsies were obtained to determine the extent of healing.
  
  
  RESULTS
  There were no significant differences between subgroups having the same ostium patency. However, compared to the subgroups with patent ostia, corresponding subgroups with semi-patent ostia exhibited significantly increased nasal smear and nasal biopsy scores starting from the second week.
  
  
  CONCLUSIONS
  The degree of ostial patency seems to have a significant role in the treatment of acute maxillary sinusitis.
authors.affiliation: Department of Otolaryngology, Medicine Faculty of Yüzüncü Yil University, Van, Turkey. ahkutluhan@hotmail.com
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kutluhan
authors.forename: Emin
authors.initials: E
authors.lastname: Inalkaç
authors.forename: A Faruk
authors.initials: AF
authors.lastname: Kiroğlu
authors.forename: Nusret
authors.initials: N
authors.lastname: Akpolat
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Kiriş
mesh_terms: D000208:Acute Disease; D000281:Administration, Intranasal; D000284:Administration, Oral; D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D004195:Disease Models, Animal; D008443:Maxillary Sinus / Q000473:pathology; D015523:Maxillary Sinusitis / Q000188:drug therapy* / Q000473:pathology; D014663:Nasal Decongestants / Q000008:administration & dosage; D009297:Nasal Mucosa / Q000473:pathology; D010109:Oxymetazoline / Q000008:administration & dosage; D011817:Rabbits; D012965:Sodium Chloride / Q000008:administration & dosage; D013256:Steroids
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D014663:Nasal Decongestants; D013256:Steroids; D012965:Sodium Chloride; D010109:Oxymetazoline