title: Effect of genotype on behavioral and hormonal components of sexual activation of male mice.
abstract: Possible relationship between changes in behavior and hormone response to a sex stimulus was studied by comparing these parameters in mice of 10 genotypes. All males spent more time near the wall during the very first 5 min after appearance of the female. Strains with the minimum (DBA/2, C57Bl/6J) and maximum (SWR, CBA) time spent near the wall were distinguished. Genotypical differences in hormone response during sexual activation were detected. Considerable increase in testosterone concentration in the peripheral blood was observed in males of 6 of the 10 mouse strains 30 min after appearance of the female. Mouse strains with contrast sexual activation were distinguished. No correlation between behavioral and hormonal response was detected. The detected genetically determined variability of the behavioral and hormonal components of sexual activation is determined by hereditary peculiarities of central mechanisms regulating the studied functions.
authors.affiliation: Laboratory of Behavioral Phenogenetics, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk. amst@bionet.nsc.ru
authors.forename: T G
authors.initials: TG
authors.lastname: Amstislavskaya
authors.forename: M V
authors.initials: MV
authors.lastname: Khrapova
mesh_terms: D000818:Animals; D005260:Female; D005838:Genotype; D006728:Hormones / Q000378:metabolism*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008811:Mice, Inbred DBA; D008813:Mice, Inbred ICR; D012726:Sexual Behavior, Animal; D013045:Species Specificity; D013739:Testosterone / Q000097:blood; D013997:Time Factors
chemical_list: D006728:Hormones; D013739:Testosterone