title: Antifungal constituents of the essential oil fraction of Artemisia dracunculus L. Var. dracunculus.
abstract: The isolation and structure elucidation of antifungal constituents of the steam-distilled essential oil fraction of Artemisia dracunculus are described. Antifungal activities of 5-phenyl-1,3-pentadiyne and capillarin against Colletrotichum fragariae, Colletrotichum gloeosporioides, and Colletrotichum acutatum are reported for the first time. The relative abundance of 5-phenyl-1,3-pentadiyne is about 11% of the steam-distilled oil, as determined by GC-MS. Methyleugenol was also isolated and identified as an antifungal constituent of the oil.
authors.affiliation: Agricultural Research Service, U.S. Department of Agriculture, Natural Product Utilization Research Unit, University Of Mississippi, University, Mississippi 38677, USA. kmeepaga@olemiss.edu
authors.forename: Kumudini M
authors.initials: KM
authors.lastname: Meepagala
authors.forename: George
authors.initials: G
authors.lastname: Sturtz
authors.forename: David E
authors.initials: DE
authors.lastname: Wedge
mesh_terms: D019306:Artemisia / Q000737:chemistry*; D020231:Colletotrichum / Q000187:drug effects; D005054:Eugenol / Q000031:analogs & derivatives* / Q000032:analysis / Q000494:pharmacology; D005659:Fungicides, Industrial / Q000032:analysis* / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D009822:Oils, Volatile / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry*
chemical_list: D005659:Fungicides, Industrial; D009822:Oils, Volatile; D010938:Plant Oils; C005223:methyleugenol; D005054:Eugenol