Value of the plasma protein and hemoglobin concentration in the diagnosis of pulmonary edema in scorpion sting patients.
OBJECTIVE
To investigate the value of measuring total plasma protein and hemoglobin concentrations for the diagnosis of pulmonary edema secondary to scorpion envenomation.


METHODS
Retrospective study over a 4-year period in the medical intensive care unit of a university hospital.


METHODS
67 patients older than 3 years admitted in the intensive care unit for scorpion envenomation and stratified into two groups according to the presence of pulmonary edema assessed by a medical committee that took into account clinical, radiological, and blood gas data at admission and after treatment. Total plasma protein and hemoglobin concentrations were analyzed separately.


RESULTS
At admission all patients with and without pulmonary edema exhibited polypnea and tachycardia. The mean plasma protein and hemoglobin concentrations were higher in patients with pulmonary edema (74+/-6 and 14.2+/-2.0 g/dl, respectively) than in those without pulmonary edema (64+/-6 and 12.3+/-1.4 g/dl). After 24 h plasma protein and hemoglobin concentrations decreased in the pulmonary edema group (-11 and -1.9 g/dl) despite a negative fluid balance (-500 ml). A plasma protein concentration of 70 g/l or more predicted the presence of pulmonary edema with a sensitivity of 80% a specificity of 96%, a positive predictive value of 97%, and negative predictive value of 77%.


CONCLUSIONS
In scorpion-envenomed patients with cardiorespiratory manifestations high plasma protein and hemoglobin concentrations suggest the presence of pulmonary edema.
Bahloul
Mabrouk
M
Service de Réanimation médicale, CHU Habib Bourguiba, Route el Ain Km 1, 3029 Sfax Tunisia. bahloulmab@yahoo.fr
Bouaziz
Mounir
M
Dammak
Hassen
H
Ben Hamida
Chokri
C
Ksibi
Hichem
H
Rekik
Noureddine
N
Chelly
Hedi
H
Teboul
Jean Louis
JL
Kallel
Hatem
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001733:Bites and Stings; D001798:Blood Proteins / Q000032:analysis*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D005260:Female; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011654:Pulmonary Edema / Q000175:diagnosis* / Q000209:etiology*; D012372:ROC Curve; D012189:Retrospective Studies; D012604:Scorpion Venoms / Q000009:adverse effects*; D018709:Statistics, Nonparametric
D001798:Blood Proteins; D006454:Hemoglobins; D012604:Scorpion Venoms