Tailoring natural effector functions. Antibody engineering beyond humanization.
Brekke
Ole H
OH
Affitech AS, Oslo, Norway.
Thommesen
John E
JE
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis* / Q000235:genetics / Q000276:immunology / Q000627:therapeutic use*; D002478:Cells, Cultured; D017931:DNA Primers / Q000737:chemistry; D015195:Drug Design; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis* / Q000235:genetics / Q000276:immunology*; D016296:Mutagenesis / Q000235:genetics* / Q000276:immunology; D016133:Polymerase Chain Reaction / Q000379:methods*; D015202:Protein Engineering / Q000379:methods*
D000911:Antibodies, Monoclonal; D017931:DNA Primers; D007074:Immunoglobulin G