title: The boosting of didanosine by allopurinol permits a halving of the didanosine dosage.
authors.affiliation: Department of Internal Medicine and Infectious Diseases, Algemeen Ziekenhuis St Jan, Brugge, Belgium.
authors.forename: Johan R
authors.initials: JR
authors.lastname: Boelaert
authors.forename: Geneviève M
authors.initials: GM
authors.lastname: Dom
authors.forename: Alwin D
authors.initials: AD
authors.lastname: Huitema
authors.forename: Jos H
authors.initials: JH
authors.lastname: Beijnen
authors.forename: Joep M
authors.initials: JM
authors.lastname: Lange
mesh_terms: D000328:Adult; D000493:Allopurinol / Q000008:administration & dosage* / Q000493:pharmacokinetics; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D016049:Didanosine / Q000008:administration & dosage* / Q000493:pharmacokinetics; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004791:Enzyme Inhibitors / Q000008:administration & dosage* / Q000493:pharmacokinetics; D005260:Female; D006679:HIV Seropositivity / Q000097:blood / Q000188:drug therapy*; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D008297:Male; D010865:Pilot Projects; D012367:RNA, Viral / Q000097:blood*
chemical_list: D019380:Anti-HIV Agents; D004791:Enzyme Inhibitors; D012367:RNA, Viral; D000493:Allopurinol; D016049:Didanosine; D006918:Hydroxyurea