title: Predictors of course and outcome in hypochondriasis after cognitive-behavioral treatment.
abstract: BACKGROUND
  Predictors of treatment outcome were evaluated in a clinical sample suffering from hypochondriasis.
  
  
  METHODS
  The sample consisted of 96 patients with hypochondriacal disorder according to DSM-IV or high syndrome scores on the Illness Attitude Scales (IAS) or Whiteley Index (WI). After intense inpatient cognitive-behavioral treatment (CBT), 60% of the patients were classified as responders because of substantial improvements or recovery from hypochondriacal symptomatology.
  
  
  RESULTS
  Non-responders were characterized by a higher degree of pre-treatment hypochondriasis, more somatization symptoms and general psychopathology (SCL-90R), more dysfunctional cognitions related to bodily functioning, higher levels of psychosocial impairments, and more utilization of the health care system as indicated by the number of hospital days and costs for inpatient treatments and medication. No predictive value was found for sociodemographic variables, comorbidity with other mental disorders and chronicity. Multiple linear regression showed that pre-treatment variables significantly predicted IAS scores at post-treatment (R(2) = 0.59), changes during treatment (0.10), IAS scores at follow-up two years later (0.41) and changes between baseline and follow-up (0.25).
  
  
  CONCLUSIONS
  The results demonstrate the relevance of various psychopathological variables and health care utilization as important indicators for outcome and further course of clinical hypochondriasis.
authors.affiliation: Roseneck Center of Behavioral Medicine, Prien, Germany. hiller@mail.uni-mainz.de
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Hiller
authors.forename: Rolf
authors.initials: R
authors.lastname: Leibbrand
authors.forename: Winfried
authors.initials: W
authors.lastname: Rief
authors.forename: Manfred M
authors.initials: MM
authors.lastname: Fichter
mesh_terms: D000328:Adult; D000368:Aged; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D006998:Hypochondriasis / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012044:Regression Analysis; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome