title: Risk factors associated with the development of infection with linezolid- and vancomycin-resistant Enterococcus faecium.
abstract: This retrospective cohort study revealed that linezolid resistance in vancomycin-resistant Enterococcus faecium was dependent on prior linezolid exposure and duration of linezolid therapy. These strains of E. faecium were resistant to the entire class of oxazolidinones.
authors.affiliation: College of Pharmacy, University of New Mexico, Albuquerque, NM, USA.
authors.forename: Manjunath P
authors.initials: MP
authors.lastname: Pai
authors.forename: Keith A
authors.initials: KA
authors.lastname: Rodvold
authors.forename: Paul C
authors.initials: PC
authors.lastname: Schreckenberger
authors.forename: Ronald D
authors.initials: RD
authors.lastname: Gonzales
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Petrolatti
authors.forename: John P
authors.initials: JP
authors.lastname: Quinn
mesh_terms: D000081:Acetamides / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016984:Enterococcus faecium; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D000069349:Linezolid; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D023303:Oxazolidinones / Q000494:pharmacology*; D012307:Risk Factors; D020713:Vancomycin Resistance / Q000502:physiology*
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D000069349:Linezolid