Effects of divided attention on episodic memory in chronic traumatic brain injury: a function of severity and strategy.
Eleven patients with mild traumatic brain injury (MTBI) and 13 patients with moderate-to-severe TBI (STBI) were compared to 10 matched controls on episodic memory for pictorial scene-object associations (e.g. kitchen-bread) and a range of standardized neuropsychological tests of memory and frontal-lobe functions. We tested the hypothesis that deficits in episodic memory result from impaired attentional resources and/or strategic control by manipulating attentional load at encoding (focused versus divided attention) and environmental support at retrieval (free recall and recalled cued by scene versus recognition of object and scene). Patients with TBI were disproportionately affected by the divided attention manipulation, but this effect was modulated by injury severity and encoding strategy. Overall, MTBI patients were impaired only when items were encoded under divided attention, indicating memory deficits that were secondary to deficits in the executive control. STBI patients could be differentiated into two distinct functional subgroups based on whether they favored a strategy of attending to the encoding or digit-monitoring task. The subgroup favoring the digit-monitoring task demonstrated deficits in the focused attention condition, and disproportionate memory deficits in the divided attention condition. In contrast, the subgroup favoring the encoding task demonstrated intact performance across all memory measures, regardless of attentional load, and despite remarkable similarity to the other STBI subgroup on demographic, neuropsychological, and acute injury severity measures. We discuss these outcome differences in terms of the relationship between strategy and executive control and highlight the need for more sensitive anatomical and behavioral measurement at both acute and chronic stages of injury.
Mangels
Jennifer A
JA
Department of Psychology, Schermerhorn Hall, Columbia University, 1190 Amsterdam Avenue, New York, NY 10027, USA. mangels@psych.columbia.edu
Craik
Fergus I M
FI
Levine
Brian
B
Schwartz
Michael L
ML
Stuss
Donald T
DT
D000328:Adult; D001288:Attention; D001921:Brain / Q000503:physiopathology; D001930:Brain Injuries / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D003463:Cues; D005260:Female; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology; D011939:Mental Recall; D009483:Neuropsychological Tests; D021641:Recognition, Psychology; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed