title: Synthesis, structural characterization and antimicrobial studies of hydrazone derivatives of 3-hydroxyimino-5-methyl-2-hexanone.
abstract: The derivatives of 3-hydroxyimino-5-methyl-2-hexanone oxime have been obtained in good yield by its reactions either with hydrazine hydrate or phenyl hydrazine, respectively. IR and 1H NMR spectral data of these compounds have been discussed. All the newly synthesised compounds have been tested for their biological activity against S. auerus, S. typhi, C. albicans, A. niger, S. cerevisiae and M. tuberculosis H47RV.
authors.affiliation: Department of Chemistry, The Institute of Science, Mumbai, India.
authors.forename: Kamini J
authors.initials: KJ
authors.lastname: Donde
authors.forename: Vishwanath R
authors.initials: VR
authors.lastname: Patil
authors.forename: Shilpa S
authors.initials: SS
authors.lastname: Utekar
authors.forename: Sheela P
authors.initials: SP
authors.lastname: Malve
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006588:Hexanones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006835:Hydrazones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000706:statistics & numerical data; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D006588:Hexanones; D006835:Hydrazones; D010091:Oximes