Antimicrobial susceptibility profiles of clinically relevant blood culture isolates from nine surgical intensive care units, 1996-2000.
In order to elucidate trends in the incidence and susceptibility profiles of causative agents of bacteremia/fungemia in nine surgical intensive care units, a total of 744 isolates obtained during a 5-year period (1996-2000) were studied. The isolates included 698 bacteria and 46 fungi obtained from 523 positive blood cultures, representing 317 episodes of bacteremia/fungemia. Methicillin-resistant Staphylococcus aureus accounted for 2.3 episodes per 1000 surgical ICU admissions in 1996, 1.6 in 1997, 0.3 in 1998, 0.6 in 1999, and 1.7 in 2000. One Enterococcus faecalis (VanA) isolate resistant to both vancomycin and teicoplanin was recovered in 1996. Ciprofloxacin resistance in Pseudomonas aeruginosa decreased from 36% in 1996 to 20% in 2000, and resistance to third-generation cephalosporins decreased from 40% in 1996 to 9% in 2000. In light of differences between these results and those found elsewhere, these findings might prove useful for making infection control policy decisions in intensive care units.
Assadian
O
O
Clinical Institute for Hygiene and Medical Microbiology, University of Vienna Division of Hospital Hygiene, University Hospital Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. ojan.assadian@akh-wien.ac.at
Apfalter
P
P
Assadian
A
A
Makristathis
A
A
Daxboeck
F
F
Koller
W
W
Hirschl
A M
AM
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001317:Austria / Q000453:epidemiology; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D001769:Blood / Q000382:microbiology*; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D003625:Data Collection; D004352:Drug Resistance, Microbial; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D006094:Gram-Positive Bacteria / Q000302:isolation & purification*; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D008297:Male; D008826:Microbial Sensitivity Tests; D015337:Multicenter Studies as Topic; D012189:Retrospective Studies; D012307:Risk Factors; D013503:Surgery Department, Hospital / Q000706:statistics & numerical data
D000900:Anti-Bacterial Agents