Mechanisms of hemopoiesis in athymic mice.
Cell elements of peripheral blood and bone marrow and splenic hemopoiesis were studied in athymic BALB/c mice (nude or thymectomized animals). In athymic animals lympho- and erythropoiesis were suppressed, while granulocyto- and monocytopoiesis were activated. These changes were more pronounced in nude mice.
Zhdanov
V V
VV
Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
Luk'yanova
T A
TA
Kirienkova
E V
EV
D000818:Animals; D001854:Bone Marrow Cells / Q000378:metabolism; D006410:Hematopoiesis; D006720:Homozygote; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D013234:Stem Cells / Q000166:cytology; D013601:T-Lymphocytes / Q000502:physiology*; D013950:Thymus Gland / Q000502:physiology*