The use of animal infection models to study the pathogenesis of melioidosis and glanders.
The use of animal infection models is central to the study of microbial pathogenesis. In combination with genetic, immunological and antigen purification techniques, much can be learned regarding the pathogenesis of diseases caused by microorganisms. This update focuses on the recent use of animal infection models to study the pathogenesis of melioidosis and glanders.
Woods
Donald E
DE
Dept of Microbiology and Infectious Diseases, Faculty of Medicine, University of Calgary Health Sciences Center, 3330 Hospital Drive, NW, Alberta, Canada T2N 4NI. woods@ucalgary.ca
D000818:Animals; D019117:Burkholderia / Q000235:genetics / Q000472:pathogenicity*; D016957:Burkholderia pseudomallei / Q000235:genetics / Q000472:pathogenicity; D006224:Cricetinae; D004195:Disease Models, Animal; D005798:Genes, Bacterial; D005896:Glanders / Q000209:etiology* / Q000382:microbiology; D008554:Melioidosis / Q000209:etiology*; D051379:Mice; D014774:Virulence / Q000235:genetics