title: Grafting of synthetic mannose receptor-ligands onto onion vectors for human dendritic cells targeting.
abstract: A practical preparation of onion vesicles targeted to dendritic cells involves the grafting of mannose-mimetic clusters, bearing a hydrazino group, onto the surface of onion vesicles containing an aldehyde functionalized lipid.
authors.affiliation: CRPP, CNRS 8641, Pessac, Université de Bordeaux 1, France.
authors.forename: Pascale
authors.initials: P
authors.lastname: Chenevier
authors.forename: Cyrille
authors.initials: C
authors.lastname: Grandjean
authors.forename: Estelle
authors.initials: E
authors.lastname: Loing
authors.forename: Frédéric
authors.initials: F
authors.lastname: Malingue
authors.forename: Gerhild
authors.initials: G
authors.lastname: Angyalosi
authors.forename: Hélène
authors.initials: H
authors.lastname: Gras-Masse
authors.forename: Didier
authors.initials: D
authors.lastname: Roux
authors.forename: Oleg
authors.initials: O
authors.lastname: Melnyk
authors.forename: Line
authors.initials: L
authors.lastname: Bourel-Bonnet
mesh_terms: D020650:Combinatorial Chemistry Techniques; D003713:Dendritic Cells / Q000737:chemistry / Q000378:metabolism*; D016503:Drug Delivery Systems / Q000379:methods; D006801:Humans; D037181:Lectins, C-Type / Q000378:metabolism*; D008024:Ligands; D008081:Liposomes / Q000138:chemical synthesis / Q000493:pharmacokinetics* / Q000627:therapeutic use; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins / Q000378:metabolism*; D018613:Microscopy, Confocal; D011956:Receptors, Cell Surface / Q000378:metabolism*
chemical_list: D037181:Lectins, C-Type; D008024:Ligands; D008081:Liposomes; D000090323:Mannose Receptor; D037241:Mannose-Binding Lectins; D011956:Receptors, Cell Surface