title: Thromboprophylaxis with low molecular weight heparin in thrombophilia-complicated pregnancy.
abstract: We treated three thrombophilia-complicated pregnant women (two antiphospholipid antibody syndrome, one protein C deficiency) with low molecular weight heparin (dalteparin). All three pregnancies including one twin pregnancy ended in live births without a decrease in bone mineral density. This treatment modality was effective and safe preventing thrombosis during their pregnancies.
authors.affiliation: Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan. yasuhiko-ebina@hokkaido.med.or.jp
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Ebina
authors.forename: Hideto
authors.initials: H
authors.lastname: Yamada
authors.forename: Emi H
authors.initials: EH
authors.lastname: Kato
authors.forename: Ritsu
authors.initials: R
authors.lastname: Yamamoto
authors.forename: Noriaki
authors.initials: N
authors.lastname: Sakuragi
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Fujimoto
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000188:drug therapy; D017985:Dalteparin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000517:prevention & control*; D011256:Pregnancy Outcome; D020151:Protein C Deficiency / Q000188:drug therapy; D013923:Thromboembolism / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants; D017985:Dalteparin