title: Detection of covalent tetrahedral adducts by differential isotope shift 13C NMR: acetyl-enzyme reaction intermediate formed by 3-hydroxy-3-methylglutaryl-CoA synthase.
authors.affiliation: Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.
authors.forename: Henry M
authors.initials: HM
authors.lastname: Miziorko
authors.forename: Dmitriy A
authors.initials: DA
authors.lastname: Vinarov
mesh_terms: D000214:Acyl Coenzyme A / Q000737:chemistry / Q000378:metabolism; D002244:Carbon / Q000737:chemistry / Q000378:metabolism; D003066:Coenzyme A Ligases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D006904:Hydroxymethylglutaryl-CoA Synthase; D007554:Isotopes / Q000737:chemistry / Q000378:metabolism; D008345:Manganese / Q000378:metabolism; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D010100:Oxygen / Q000737:chemistry / Q000378:metabolism
chemical_list: D000214:Acyl Coenzyme A; D007554:Isotopes; C010667:acetoacetyl CoA; D008345:Manganese; D002244:Carbon; D006904:Hydroxymethylglutaryl-CoA Synthase; D003066:Coenzyme A Ligases; D010100:Oxygen