title: gamma-Glutamyltranspeptidase and gamma-glutamyl peptide ligases: fluorophosphonate and phosphonodifluoromethyl ketone analogs as probes of tetrahedral transition state and gamma-glutamyl-phosphate intermediate.
authors.affiliation: Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Hiratake
authors.forename: Makoto
authors.initials: M
authors.lastname: Inoue
authors.forename: Kanzo
authors.initials: K
authors.lastname: Sakata
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000345:Affinity Labels / Q000737:chemistry / Q000378:metabolism; D000409:Alanine / Q000031:analogs & derivatives; D000613:Aminobutyrates / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003980:Diazooxonorleucine / Q000737:chemistry / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry / Q000378:metabolism*; D005459:Fluorides / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D007555:Isoxazoles / Q000737:chemistry / Q000378:metabolism; D007668:Kidney / Q000201:enzymology; D008025:Ligases / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure; D010710:Phosphates / Q000737:chemistry / Q000378:metabolism*; D021241:Spectrometry, Mass, Electrospray Ionization; D005723:gamma-Glutamyltransferase / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000378:metabolism*
chemical_list: D000345:Affinity Labels; D000613:Aminobutyrates; D004791:Enzyme Inhibitors; D029968:Escherichia coli Proteins; D005456:Fluorescent Dyes; D007555:Isoxazoles; D010710:Phosphates; D003980:Diazooxonorleucine; C012980:fluorophosphate; C028141:4-(phosphonoacetyl)-L-alpha-aminobutyrate; D000255:Adenosine Triphosphate; D005723:gamma-Glutamyltransferase; D008025:Ligases; C006303:acivicin; D000409:Alanine; D005459:Fluorides