title: An exclusively intraabdominal distal esophageal segment prevents primary delayed anastomosis in children with pure esophageal atresia.
abstract: OBJECTIVE
  The aim of this study was to evaluate the outcome of children with pure esophageal atresia (EA) managed by the strategy of delayed primary anastomosis and to find parameters to identify which of these children will have satisfactory esophageal growth to permit a successful primary esophageal anastomosis.
  
  
  METHODS
  Sixteen children with pure EA were treated by delayed anastomosis strategy from June 1992 to May 2001 at the Instituto da Criança-University of São Paulo Medical School. The treatment consisted of creating an early feeding gastrostomy, continuous upper pouch suction, and periodic radiologic/endoscopic assessments of the gap between the superior and inferior esophageal pouches. The first assessment was done 4 weeks after the initial gastrostomy. Subsequent assessments were done, when necessary, 4 to 10 weeks after the first one. Children with the gap between the pouches corresponding to 2 vertebral bodies or less were considered for primary repair.
  
  
  RESULTS
  The waiting period ranged from 8 to 14 weeks. Five children were considered for primary repair (31.3%). All of them had an end-to-end esophageal anastomosis performed without tension. Eleven children (68.7%) did not show significant esophageal growth after the waiting period and were not considered for primary esophageal anastomosis. Eight of them (50%) showed an entirely intraabdominal distal pouch at the first assessment.
  
  
  CONCLUSIONS
  (1) Infants with an exclusively intraabdominal distal pouch at the first evaluation will not reach sufficient elongation of the pouches and should be considered early as a candidate for esophageal replacement. (2) Combined radiologic/endoscopic assessment and the measurement of the gap in terms of vertebral bodies is a practical and reliable method to predict the feasibility of primary anastomosis. (3) Using these criteria, primary anastomosis could be accomplished in less than a third of cases.
authors.affiliation: Pediatric Surgery Division, Department of Pediatric Surgery, University of São Paulo Medical School, São Paulo, Brazil.
authors.forename: João Gilberto
authors.initials: JG
authors.lastname: Maksoud-Filho
authors.forename: Manoel Ernesto P
authors.initials: ME
authors.lastname: Gonçalves
authors.forename: Uenis
authors.initials: U
authors.lastname: Tannuri
authors.forename: João Gilberto
authors.initials: JG
authors.lastname: Maksoud
mesh_terms: D000714:Anastomosis, Surgical; D004933:Esophageal Atresia / Q000000981:diagnostic imaging / Q000601:surgery*; D004947:Esophagus / Q000000981:diagnostic imaging / Q000254:growth & development; D005240:Feasibility Studies; D005471:Fluoroscopy; D005774:Gastrostomy; D006801:Humans; D007231:Infant, Newborn; D007902:Length of Stay; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014850:Waiting Lists