Systemic endotoxemia during chronic viral hepatitis.
Incidence and severity of systemic endotoxemia in patients with chronic viral hepatitis B and C were studied using the limulus test. Healthy subjects and patients with acute viral hepatitis B and C comprised reference groups. The incidence of "physiological" systemic endotoxemia in healthy subjects was 31.3%, while in chronic hepatitis systemic endotoxemia was found in 69-84% patients and it was more severe in this case. A significant correlation was revealed between systemic endotoxemia with virus replication and the degree of basic clinical and laboratory signs in patients with chronic viral hepatitis B.
Sozinov
A S
AS
Kazan State Medical University. uchast@kgmu.ru
D000293:Adolescent; D000328:Adult; D001663:Bilirubin / Q000097:blood; D019446:Endotoxemia / Q000150:complications / Q000175:diagnosis* / Q000517:prevention & control; D005260:Female; D019694:Hepatitis B, Chronic / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008033:Limulus Test; D008297:Male
D001663:Bilirubin