title: [Effective use of TS-1 in a case of advanced gastric cancer, both in treating the tumor and in maintaining the patient's quality of life].
abstract: A 60-year-old man was admitted to our hospital suffering from discomfort in the epigastrium. Endoscopic examination revealed stenosis from the fornix to the body of the stomach. The lesion had invaded the lower esophagus. Biopsy specimens confirmed poorly differentiated adenocarcinoma. An abdominal CT scan showed the lesion was a single mass in the stomach and swollen lymph nodes at the fornix, and revealed slight ascites and left hydronephrosis. The patient received oral administration of TS-1. No adverse effect was seen after 3 courses of treatment, and the lesion was reduced so that it was only found in the fornix. During the 1 year and 3 months of treatment with TS-1, this patient worked as mountain guide in the Hida area and was able to travel to the Himalayas in Nepal for the New Year of 2001. To preserve the quality of life of cancer patients, it is worth considering outpatient treatment with TS-1.
authors.affiliation: Dept. of Internal Medicine, Takayama Red Cross Hospital.
authors.forename: Junko
authors.initials: J
authors.lastname: Shiroko
authors.forename: Naoe
authors.initials: N
authors.lastname: Goto
authors.forename: Koutaro
authors.initials: K
authors.lastname: Yoshimura
authors.forename: Takaya
authors.initials: T
authors.lastname: Oonishi
authors.forename: Minoru
authors.initials: M
authors.lastname: Nakai
authors.forename: Hisao
authors.initials: H
authors.lastname: Asano
authors.forename: Masato
authors.initials: M
authors.lastname: Ukita
authors.forename: Shinobu
authors.initials: S
authors.lastname: Tanabashi
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kametani
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000523:psychology; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D011725:Pyridines / Q000008:administration & dosage / Q000627:therapeutic use*; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000523:psychology; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid