Indigoferabietone, a novel abietane diterpenoid from Indigofera longeracemosa with potential antituberculous and antibacterial activity.
From the stems of Indigofera longeracemosa, a novel abietane diterpenoid, indigoferabietone was isolated. The structure was established by spectral techniques. The inhibitory activity of indigoferabietone (1) tested against Mycobacterium tuberculosis and Candida albicans, and the antibacterial activity tested against Staphylococcus aureus, Proteus vulgaris, and Escherichia coli were found to be significant.
Thangadurai
D
D
Department of Botany, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India. dthangadurai@yahoo.com
Viswanathan
M B
MB
Ramesh
N
N
D045784:Abietanes; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D000995:Antitubercular Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D029883:Indigofera / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D018547:Plant Stems / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D045784:Abietanes; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000995:Antitubercular Agents; D004224:Diterpenes; C468968:indigoferabietone