Relapsed non-Hodgkin's lymphoma diagnosed by flexible bronchoscopy.
Pulmonary relapse of non-Hodgkin's lymphoma (NHL) occurred in a 10-year-old girl who presented with cough, blood-tinged sputum, and chest tightness. The diagnosis of Ki-1 (CD30) anaplastic large-cell lymphoma was established using bronchoalveolar lavage (BAL) and transbronchial biopsy (TBB). These procedures demonstrated malignant cells that stained positive for CD30 and had the t(2;5) translocation, thereby avoiding the need for an open lung biopsy.
Phadke
Shruti M
SM
Division of Pulmonology, Department of Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15116, USA.
Chini
Barbara A
BA
Patton
Donna
D
Goyal
Rakesh K
RK
D000293:Adolescent; D001706:Biopsy; D018893:Bronchoalveolar Lavage; D001999:Bronchoscopy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis*; D012008:Recurrence