Effects of high temperature and noise on erythrocyte membrane ATPase activity in pilots during flight.
Objective. To determine the effect of heat and noise on erythrocyte membrane ATPase activities in pilots during flying. Method. Twenty-four pilots performing bombing for 3 h (45-53 degrees C, 122-97 dB in the cabin) served as the subjects. 21 ground personnel served as control (27 degrees C in the room). Blood samples were taken from both groups before flying (6:00 a.m.), and immediately (12:00 a.m.) and 8 h (8:00 p.m.) after flying. Na(+)-K+ ATPase, and Ca2(+)-Mg2+ ATPase activities in erythrocyte membrane were determined with colorimetry. Result. The Na(+)-K+ ATPase activity in erythrocyte membrane at 6:00 a.m. in pilots was higher than that in control group at the same time (P<0.01). The Ca2(+)-Mg2+ ATPase activities in erythrocyte membrane at 12:00 a.m. and 8:00 p.m. in pilots were significantly higher, compared with those in control group at the same time (P<0.01). Conclusion. The ATPase values obtained in our study were all within normal range, and the daytime variation of both groups are the same. Exposure of human body to heat and noise for long time may be harmful, the higher ATPase activity is, the more catabolism of ATP will be. ATP exhaustion will lead to Ca2+ overload in erythrocyte thus stiffen the red cell membrane.
Qin
S Z
SZ
Naval General Hospital, Beijing, China.
Yu
Q F
QF
Ma
G X
GX
Hao
W W
WW
Li
M G
MG
Zhao
H
H
D000328:Adult; D000337:Aerospace Medicine; D000401:Aircraft; D001359:Aviation; D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism*; D002681:China; D004910:Erythrocyte Membrane / Q000201:enzymology*; D006358:Hot Temperature; D006801:Humans; D008889:Military Personnel; D009622:Noise; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
D017301:Ca(2+) Mg(2+)-ATPase; D000254:Sodium-Potassium-Exchanging ATPase