title: Right ventricular pressure dynamics during exercise: relationship to stress echocardiography.
abstract: Thorough evaluation of myocardial function remains difficult to evaluate under exercising conditions. This study described right ventricular (RV) pressure dynamics during and immediately following exercise. Nine Thoroughbreds without evidence of cardiac disease completed treadmill exercise at 110% of the speed necessary to elicit VO2max while RV pressures were recorded. RV pressure dynamics were calculated at rest, maximal speed and at 10 s intervals for 2 min after exercise. Stress echocardiography was performed at rest and within 120 s after exercise. Mean dP/dtmax and dP/dtmin values were significantly greater at maximal speed and up to 30 s immediately postexercise than at rest and all time points from 60 to 120 s postexercise. Mean dP/dtmax and dP/dtmin were not significantly different from resting values after 60 s postexercise. Tau (the time constant for ventricular relaxation) decreased significantly with exercise, but was not significantly different from rest at time points from 60 to 120 s following exercise. Mean % fractional shortening (FS) increased postexercise; however, the coefficient of variability was large. Wall motion indices also showed large variability postexercise. These temporal changes in normal horses suggest that exercising RV pressure dynamics may provide a better estimation of cardiac function during exercise than postexercise stress echocardiography.
authors.affiliation: Department of Clinical Studies, University of Pennsylvania, Kennett Square 19348, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Durando
authors.forename: V B
authors.initials: VB
authors.lastname: Reef
authors.forename: E K
authors.initials: EK
authors.lastname: Birks
mesh_terms: D000818:Animals; D025401:Echocardiography, Stress / Q000662:veterinary*; D005080:Exercise Test / Q000662:veterinary; D005260:Female; D006736:Horses / Q000502:physiology*; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology*; D012016:Reference Values; D013997:Time Factors; D016278:Ventricular Function, Right / Q000502:physiology*