title: Effect of pine resin and Biopin ointment on T and B cell immunity.
abstract: We studied the effects of pine resin and Biopin ointment used for the therapy of burns, wounds, purulent and inflammatory diseases on differentiation of T lymphocyte precursors, lymphocyte proliferation in the thymus and spleen, and production of tumor necrosis factor and interleukins 1, 2, and 6 by splenocytes and peripheral blood leukocytes. The wound-healing effect of these preparations is determined by their pronounced immunomodulatory properties.
authors.affiliation: Institute of Extrapure Biological Preparations, St. Petersburg.
authors.forename: A S
authors.initials: AS
authors.lastname: Simbirtsev
authors.forename: V G
authors.initials: VG
authors.lastname: Konusova
authors.forename: G Sh
authors.initials: GSh
authors.lastname: Mchedlidze
authors.forename: E Z
authors.initials: EZ
authors.lastname: Fidarov
authors.forename: B A
authors.initials: BA
authors.lastname: Paramonov
authors.forename: V Yu
authors.initials: VY
authors.lastname: Chebotarev
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D002454:Cell Differentiation / Q000502:physiology; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009824:Ointments / Q000494:pharmacology*; D012116:Resins, Plant / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology / Q000187:drug effects; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects
chemical_list: D016207:Cytokines; D009824:Ointments; D012116:Resins, Plant; C013893:rosin