title: Effect of age on haemodynamic response to tracheal intubation. A comparison of young, middle-aged and elderly patients.
abstract: The effect of age on the haemodynamic response to tracheal intubation was studied. Ninety ASA 1 or 2 patients were divided into three groups of 30 each based on age; ie., young (18-25 years), middle-aged (40-50 years) and elderly (65-80 years). The haemodynamic response after tracheal intubation was observed as percentage change in heart rate and blood pressure compared to the baseline. Inter-group comparison was also done at different time points. The greatest percentage change in the systolic arterial pressure after tracheal tube insertion was seen in the elderly group (15%). The increase in systolic arterial pressure was significantly less in theyounggroup compared with the two older groups at one, two, three and four minutes post-intubation. The greatest percentage increase in the diastolic blood pressure compared to the baseline was seen in the middle aged group (24%). The elderly and young patients showed a significant difference in the diastolic blood pressure response only at one minute post-intubation. The heart rate response was greatest in the middle-aged patients (40%) and least in the elderly (16%). These differences may have clinical significance and should be considered in assessing and performing research into the haemodynamic response to intubation.
authors.affiliation: Department of Anaesthesiology, The Aga Khan University, Karachi, Pakistan.
authors.forename: S
authors.initials: S
authors.lastname: Ismail
authors.forename: S I
authors.initials: SI
authors.lastname: Azam
authors.forename: F A
authors.initials: FA
authors.lastname: Khan
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001794:Blood Pressure / Q000502:physiology; D015331:Cohort Studies; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects* / Q000379:methods*; D007828:Laryngoscopy / Q000009:adverse effects / Q000379:methods; D008297:Male; D008875:Middle Aged; D011336:Probability; D018570:Risk Assessment; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D013997:Time Factors