A duplex issue: (i) time to re-appraise the diagnosis and classification of von Willebrand disorder, and (ii) clarification of the roles of von Willebrand factor collagen binding and ristocetin cofactor activity assays.
Favaloro
E J
EJ
Department of Haematology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, NSW, 2145, Australia. emmanuel@icpmr.wsahs.nsw.gov.au
D003094:Collagen / Q000378:metabolism; D003937:Diagnosis, Differential; D006801:Humans; D012310:Ristocetin / Q000378:metabolism; D014842:von Willebrand Diseases / Q000175:diagnosis*; D014841:von Willebrand Factor / Q000032:analysis*
D014841:von Willebrand Factor; D012310:Ristocetin; D003094:Collagen