Apoptosis in myocardial ischaemia and infarction.
Recent studies indicate that, in addition to necrosis, apoptosis also plays a role in the process of tissue damage after myocardial infarction, which has pathological and therapeutic implications. This review article will discuss studies in which the role and mechanisms of apoptosis in myocardial infarction were analysed in vivo and in vitro in humans and in animals.
Krijnen
P A J
PA
Department of Pathology, VU University Medical Centre, PO Box 7075, 1007MB Amsterdam, The Netherlands. paj.krijnen@vumc.nl
Nijmeijer
R
R
Meijer
C J L M
CJ
Visser
C A
CA
Hack
C E
CE
Niessen
H W M
HW
D017209:Apoptosis / Q000502:physiology*; D018929:Cell Culture Techniques; D004195:Disease Models, Animal; D006801:Humans; D009203:Myocardial Infarction / Q000473:pathology; D017202:Myocardial Ischemia / Q000473:pathology*; D032383:Myocytes, Cardiac / Q000473:pathology; D009924:Organ Culture Techniques; D011506:Proteins / Q000378:metabolism
D011506:Proteins