title: Engineering hot spots for affinity enhancement of antibodies.
authors.affiliation: Human Genome Sciences Inc., Rockville, MD, USA.
authors.forename: Partha S
authors.initials: PS
authors.lastname: Chowdhury
mesh_terms: D000906:Antibodies / Q000235:genetics* / Q000276:immunology / Q000494:pharmacology*; D000915:Antibody Affinity / Q000235:genetics* / Q000276:immunology*; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D003001:Cloning, Molecular / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007135:Immunoglobulin Variable Region / Q000235:genetics* / Q000276:immunology* / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000235:genetics* / Q000276:immunology* / Q000378:metabolism; D016296:Mutagenesis; D019151:Peptide Library; D014407:Tumor Cells, Cultured
chemical_list: D000906:Antibodies; D000970:Antineoplastic Agents; D007135:Immunoglobulin Variable Region; D008562:Membrane Glycoproteins; D019151:Peptide Library