title: Muscle-fiber characteristics in adult mouse-tongue muscles.
abstract: To clarify functions of the mouse-tongue muscles, proteins such as myocin heavy chain (MHC) 2a and MHC-2b, which are isoforms of the fast-twitch fiber type myosin heavy chain, in the lateral margin of the tongue were observed by reverse transcription polymerase chain reaction and immunohistochemical analyses. The main MHC isoform in the superior longitudinal muscle of the tongue was MHC-2b, with the fastest function and the main MHC isoform in the transverse muscle of the tongue was MHC-2a. These findings suggested that the fastest function is necessary for the superior longitudinal muscle of the tongue, which is useful for moving the tongue in and out of the mouth in the sagittal direction, showing different cellular biological properties of the myofibers from those of the transverse muscle of the tongue.
authors.affiliation: Oral Health Science Center, Department of Anatomy, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan. shinabe@tdc.ac.jp
authors.forename: Shinichi
authors.initials: S
authors.lastname: Abe
authors.forename: Masayo
authors.initials: M
authors.lastname: Maejima
authors.forename: Hiroki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Takahiko
authors.initials: T
authors.lastname: Shibahara
authors.forename: Hiroko
authors.initials: H
authors.lastname: Agematsu
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Doi
authors.forename: Koji
authors.initials: K
authors.lastname: Sakiyama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Usami
authors.forename: Kazuro
authors.initials: K
authors.lastname: Gojyo
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Hashimoto
authors.forename: Masao
authors.initials: M
authors.lastname: Yoshinari
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Ide
mesh_terms: D000818:Animals; D018076:DNA, Complementary / Q000032:analysis; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018656:Muscle Fibers, Fast-Twitch / Q000145:classification / Q000166:cytology / Q000378:metabolism; D018657:Muscle Fibers, Slow-Twitch / Q000145:classification / Q000166:cytology / Q000378:metabolism; D018482:Muscle, Skeletal / Q000166:cytology / Q000378:metabolism*; D009218:Myosins / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D020033:Protein Isoforms; D012333:RNA, Messenger / Q000032:analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014059:Tongue / Q000166:cytology*
chemical_list: D018076:DNA, Complementary; D020033:Protein Isoforms; D012333:RNA, Messenger; D009218:Myosins