title: Physical and chemical limitations to preparation of beta radioactive stents by direct neutron activation.
abstract: Pure beta emitters are the sources of choice for intracoronary irradiations in restenosis prevention. In this work we reconsidered preparation of low activity 32P sources by ion-implantation of stable 31P into highly biocompatible pure titanium stents, followed by neutron activation. Gamma-spectrometrical analysis has shown that during activations with high thermal neutrons flux production of gamma-active long-lived contaminants is much beyond the dosimetrically acceptable limit, mainly due to the competing (n,p) reactions induced by the fast neutrons on isotopes of the bulk stent material, and to a lesser extent due to (n,gamma) reactions on chemical impurities. A potential applicability of this method for obtaining alternative beta radioactive stents is discussed.
authors.affiliation: The Henryk Niewodniczański Institute of Nuclear Physics, Radzikowskiego 152, 31-342 Kraków, Poland. barbara.petelenz@ifj.edu.pl
authors.forename: Barbara
authors.initials: B
authors.lastname: Petelenz
authors.forename: Bogusław
authors.initials: B
authors.lastname: Rajchel
authors.forename: Paweł
authors.initials: P
authors.lastname: Bilski
authors.forename: Ryszard
authors.initials: R
authors.lastname: Misiak
authors.forename: Mirosław
authors.initials: M
authors.lastname: Bartyzel
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Wilczek
authors.forename: Dorothea
authors.initials: D
authors.lastname: Alber
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods; D002860:Chromium Radioisotopes; D003327:Coronary Disease / Q000517:prevention & control* / Q000628:therapy*; D005720:Gamma Rays; D007477:Ions; D009502:Neutrons; D010761:Phosphorus Radioisotopes; D013053:Spectrophotometry; D015607:Stents; D014025:Titanium
chemical_list: D002860:Chromium Radioisotopes; D007477:Ions; D010761:Phosphorus Radioisotopes; D014025:Titanium