Meningeal chloroma (granulocytic sarcoma) in acute lymphoblastic leukemia mimicking a falx meningioma.
Isolated chloromas (granulocytic sarcomas) are rare tumors. Chloromas are masses composed of immature granulocytic cells. Granulocytic sarcoma occurs primarily in patients with acute myelogenous leukemia and may also arise in patients with other myeloproliferative disorders, but rarely in patients with acute lymphoblastic leukemia (ALL). When dural-based, granulocytic sarcoma may be indistinguishable from meningioma radiologically. We now describe one patient affected by ALL with isolated granulocytic sarcoma mimicking a falx meningioma as initial CNS relapses. These unusual clinical manifestation and radiological finding in ALL should be considered as recurrence of leukemia. Early detection and antileukemic treatment of granulocytic sarcoma are necessarily important for favorable prognosis.
Ahn
Jung Yong
JY
Department of Neurosurgery, Pundang CHA Hospital, Pochon University College of Medicine, Sungnam, South Korea. jyahn@cha.ac.kr
Kwon
Seong Oh
SO
Shin
Moon Soo
MS
Kang
Shin Heh
SH
Kim
Young Rae
YR
D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000556:secondary; D008579:Meningioma / Q000000981:diagnostic imaging / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma; D023981:Sarcoma, Myeloid / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed