Oxidative stress in the mussel Mytella guyanensis from polluted mangroves on Santa Catarina Island, Brazil.
Digestive glands of the mangrove mussel Mytella guyanensis, collected at one non-polluted site (site 1) and two polluted sites (sites 2 and 3), were analysed for different antioxidant defenses, lipid peroxidation and DNA damage. Thiobarbituric acid-reactive substance (TBARS) and 8-oxo-7,8-dihydro-2'-deoxyguanosine levels were enhanced at the polluted sites. With the exception of superoxide dismutase, the activities of catalase and glutathione peroxidase were also higher at the polluted sites. Greater increases were observed in glutathione reductase, glutathione S-transferase and etoxyresorufine-O-deethylase activities at the polluted sites. Conversely, reduced glutathione content was higher at the control site. Trace metal contents in mussels collected at polluted sites were increased compared to the control site, and there were strong positive correlations between TBARS and Cu and Pb contents. M. guyanensis is routinely exposed to an oxidative stress condition at both polluted sites, and considering xenobiotic bioaccumulation in bivalve molluscs, the mangrove mussel represents an excellent bioindicator for environmental monitoring studies.
Torres
Moacir Aloisio
MA
Departamento de Ecologia e Zoologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Testa
Camila Pires
CP
Gáspari
Catia
C
Masutti
Mariana Beatriz
MB
Panitz
Clarice Maria Neves
CM
Curi-Pedrosa
Rozangela
R
de Almeida
Eduardo Alves
EA
Di Mascio
Paolo
P
Filho
Danilo Wilhelm
DW
D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis; D049872:Bivalvia / Q000378:metabolism*; D001938:Brazil; D004249:DNA Damage; D004784:Environmental Monitoring / Q000379:methods*; D005618:Fresh Water; D015227:Lipid Peroxidation; D018384:Oxidative Stress; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014876:Water Pollution
D000975:Antioxidants; D015415:Biomarkers; D017392:Thiobarbituric Acid Reactive Substances