Vitamin A in the cerebrospinal fluid of patients with and without idiopathic intracranial hypertension.
We quantified vitamin A in the cerebrospinal fluid of patients with idiopathic intracranial hypertension, elevated intracranial pressure of other causes and normal intracranial pressure. Vitamin A could be detected by high-pressure liquid chromatography in most of the specimens. There was a significantly higher level of vitamin A in the cerebrospinal fluid of some patients with idiopathic intracranial hypertension. Vitamin A toxicity may play a role in the pathogenesis of idiopathic intracranial hypertension.
Warner
Judith E A
JE
Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah Health Sciences Center, 50 North Medical Drive, Salt Lake City, UT 84132, USA. judith.warner@hsc.utah.edu
Bernstein
Paul S
PS
Yemelyanov
Alexander
A
Alder
Stephen C
SC
Farnsworth
Steven T
ST
Digre
Kathleen B
KB
D000328:Adult; D002851:Chromatography, High Pressure Liquid; D035061:Control Groups; D005260:Female; D006261:Headache / Q000150:complications; D006801:Humans; D019586:Intracranial Hypertension / Q000134:cerebrospinal fluid* / Q000209:etiology; D008297:Male; D014801:Vitamin A / Q000134:cerebrospinal fluid*
D014801:Vitamin A