Current and future perspective in the management of diabetes.
Diabetes mellitus has attained epidemic proportions worldwide. It is suggested that resistin (also called Fizz 3), a cysteine. rich-protein may represent a link between obesity and insulin resistance. Uncoupling proteins are candidate genes for human obesity or type 2 diabetes mellitus. Amylin has a vital role in regulating blood glucose concentration following meals. Gluco watch biographers are safe and effective device to measure glucose every 20 minutes. Islet transplantation has had a remarkable preliminary success. Protein kinase Cbeta inhibitor was shown to reduce albuminuria and decrease statement of TGFbeta and various extracellular matrix proteins in diabetic rats.
Vishwanathan
Vijay
V
Diabetes Research Centre and MV Hospital for Diabetes, Chennai.
D000682:Amyloid / Q000008:administration & dosage*; D001786:Blood Glucose / Q000187:drug effects; D003920:Diabetes Mellitus / Q000517:prevention & control; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy*; D004704:Endocrinology / Q000592:standards / Q000639:trends*; D005260:Female; D005544:Forecasting; D006729:Hormones, Ectopic / Q000008:administration & dosage*; D006801:Humans; D007194:India; D007333:Insulin Resistance; D058228:Islet Amyloid Polypeptide; D016381:Islets of Langerhans Transplantation; D008297:Male; D009765:Obesity; D018570:Risk Assessment
D000682:Amyloid; D001786:Blood Glucose; D006729:Hormones, Ectopic; D058228:Islet Amyloid Polypeptide