title: The medical-irradiation characteristics for neutron capture therapy at the Heavy Water Neutron Irradiation Facility of Kyoto University Research Reactor.
abstract: At the Heavy Water Neutron Irradiation Facility of the Kyoto University Research Reactor, the mix irradiation of thermal and epi-thermal neutrons, and the solo irradiation of epi-thermal neutrons are available additionally to the thermal neutron irradiation, and then the neutron capture therapy (NCT) at this facility became more flexible, after the update in 1996. The estimation of the depth dose distributions in NCT clinical irradiation, were performed for the standard irradiation modes of thermal, mixed and epi-thermal neutrons, from the both sides of experiment and calculation. On the assumption that the 10B concentration in tumor part was 40 ppm and the ratio of tumor to normal tissue was 3.5, the advantage depth were estimated to 5.4, 6.0, and 8.0, for the respective standard irradiation modes. It was confirmed that the various irradiation conditions can be selected according to the target-volume conditions, such as size, depth, etc. Besides, in the viewpoint of the radiation shielding for patient, it was confirmed that the whole-body exposure is effectively reduced by the new clinical collimators, compared with the old one.
authors.affiliation: Kyoto University Research Reactor Institute, Sennan-gun, Osaka, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Sakurai
authors.forename: Tooru
authors.initials: T
authors.lastname: Kobayashi
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D017666:Deuterium Oxide; D006358:Hot Temperature; D006801:Humans; D007564:Japan; D017247:Neutron Capture Therapy / Q000295:instrumentation* / Q000379:methods*; D009502:Neutrons / Q000627:therapeutic use*; D019047:Phantoms, Imaging; D011874:Radiometry / Q000379:methods*; D013696:Temperature; D014867:Water
chemical_list: D000970:Antineoplastic Agents; D014867:Water; D017666:Deuterium Oxide