title: Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis with intrarenal aneurysms and renal arteriovenous fistulaes.
abstract: A 78-year-old Japanese man was admitted with a complaint of slight fever and weight loss. At admission, he tested positive for myeloperoxidase (MPO)-ANCA and had renal failure. An abdominal angiography revealed atrophy of the right kidney, two or more arteriovenous fistulae (AVF) in the right renal interlobular arteries, and multiple aneurysms in both kidneys. A renal biopsy specimen showed diffuse crescentic glomerulonephritis accompanied by tubulo-interstitial changes. This case suggests the possibility of some relationship between ANCA-associated vasculitides and the formation of aneurysms and AVFs.
authors.affiliation: Department of Internal Medicine, Japan Self Defense Forces Central Hospital, Tokyo.
authors.forename: Akihito
authors.initials: A
authors.lastname: Inatsu
authors.forename: Jun
authors.initials: J
authors.lastname: Shimizu
authors.forename: Satosi
authors.initials: S
authors.lastname: Ooshima
authors.forename: Susumu
authors.initials: S
authors.lastname: Matsukuma
authors.forename: Kozaburo
authors.initials: K
authors.lastname: Koga
authors.forename: Shigeyo
authors.initials: S
authors.lastname: Shiwachi
authors.forename: Teizo
authors.initials: T
authors.lastname: Ito
authors.forename: Hiroko
authors.initials: H
authors.lastname: Yasuda
authors.forename: Takao
authors.initials: T
authors.lastname: Kubota
mesh_terms: D000368:Aged; D000783:Aneurysm / Q000150:complications* / Q000000981:diagnostic imaging; D000792:Angiography; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D001164:Arteriovenous Fistula / Q000150:complications* / Q000000981:diagnostic imaging / Q000276:immunology; D005921:Glomerulonephritis / Q000150:complications* / Q000000981:diagnostic imaging / Q000276:immunology / Q000628:therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012077:Renal Artery / Q000002:abnormalities*; D006435:Renal Dialysis; D012082:Renal Veins / Q000002:abnormalities*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D005938:Glucocorticoids; D011239:Prednisolone