title: Alcoholism treatment adherence: older age predicts better adherence and drinking outcomes.
abstract: OBJECTIVE
  Adherence to treatment has been demonstrated to be an important factor for remission from alcohol dependence. The authors compared therapy and medication adherence for treatment of alcohol dependence in older adults with adherence in younger adults.
  
  
  METHODS
  All subjects were participants in a randomized, double-blind, placebo-controlled efficacy trial of naltrexone for the treatment of alcohol dependence. All subjects received a medically-based psychosocial intervention focused on motivating patients to change and on adherence to treatment. The therapy is nonconfrontational and is delivered by a nurse-practitioner.
  
  
  RESULTS
  Compared with younger adults, older adults had greater attendance at therapy sessions and greater adherence to the medication. Age-group was the only pretreatment factor associated with adherence. The greater adherence in older adults translated to less relapse than in younger adults.
  
  
  CONCLUSIONS
  Treatment for alcohol dependence can be effective for older adults. Older adults appear to respond well to a medically-oriented program that is supportive and individualized. In fact, findings from this study suggest that older adults can be treated in mixed-age treatment settings when psychotherapeutic strategies are used that are age-appropriate and delivered on an individual basis.
authors.affiliation: Section of Geriatric Psychiatry, Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA. oslin@mail.med.upenn.edu
authors.forename: David W
authors.initials: DW
authors.lastname: Oslin
authors.forename: Helen
authors.initials: H
authors.lastname: Pettinati
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Volpicelli
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000437:Alcoholism / Q000628:therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009271:Naltrexone / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000627:therapeutic use*; D016017:Odds Ratio; D010349:Patient Compliance / Q000523:psychology*; D011613:Psychotherapy; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D009292:Narcotic Antagonists; D009271:Naltrexone