Novel method for the synthesis of enamines by palladium catalyzed amination of alkenyl bromides.
The intermolecular palladium catalyzed cross-coupling reaction between secondary amines and alkenyl bromides is described for the first time, giving rise to enamines with very high yields and regioselectivity.
Barluenga
José
J
Instituto Universitario de Química Organometálica Enrique Moles, Universidad de Oviedo, Oviedo, 33071 Asturias, Spain. barluenga@sauron.quimica.uniovi.es
Fernández
M Alejandro
MA
Aznar
Fernando
F
Valdés
Carlos
C