Clinical pathological analysis and immunohistochemical study of ten solitary fibrous tumors.
OBJECTIVE
To study the clinical and pathological characteristics of solitary fibrous tumor (SFT).


METHODS
Clinical pathological analysis and immunohistochemical studies were performed on ten patients with SFT.


RESULTS
The SFTs located variously and showed different histological features. All cases showed positive staining for CD(34), VM (vimentin) and Bcl-2, but negative staining for Desmin, S-100, CK (cytokeratin) and EMA (epithelial membrane antigen).


CONCLUSIONS
SFT is described as a "patternless" growth pattern. According to clinical pathological features and immunohistochemistry, it is different from other soft tissue tumors. Long-term clinical follow-up is necessary for this kind of tumor.
Wang
Huiping
H
Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China.
Zhang
Wei
W
Yan
Liping
L
Yao
Hongtian
H
Ding
Wei
W
Yu
Xinru
X
D000328:Adult; D000368:Aged; D018952:Antigens, CD34 / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D014463:Ultrasonography; D014746:Vimentin / Q000032:analysis
D018952:Antigens, CD34; D019253:Proto-Oncogene Proteins c-bcl-2; D014746:Vimentin