The M581V mutation, associated with a mild form of congenital insensitivity to pain with anhidrosis, causes partial inactivation of the NTRK1 receptor.
Miranda
Claudia
C
Selleri
Silvia
S
Pierotti
Marco A
MA
Greco
Angela
A
D016475:3T3 Cells; D000818:Animals; D006801:Humans; D051379:Mice; D009154:Mutation; D020917:Receptor, trkA / Q000235:genetics*; D012035:Refsum Disease / Q000235:genetics*
D020917:Receptor, trkA