Up-regulated expression of the cbb(I) and cbb(II) operons during photoheterotrophic growth of a ribulose 1,5-bisphosphate carboxylase-oxygenase deletion mutant of Rhodobacter sphaeroides.
In a Rhodobacter sphaeroides ribulose 1,5-bisphosphate carboxylase-oxygenase deletion strain that requires an exogenous electron donor for photoheterotrophic growth, transcription of the genes of the Calvin-Benson-Bassham (CBB) cycle was increased. This finding pointed to a potential physiological effector that enhances the capability of the positive transcriptional activator CbbR to mediate cbb transcription. This effector is most likely ribulose 1,5-bisphosphate or a metabolite derived from this CBB pathway intermediate.
Smith
Stephanie A
SA
Department of Microbiology and Plant Molecular Biology and Biotechnology Program, The Ohio State University, Columbus, Ohio 43210-1292, USA.
Tabita
F Robert
FR
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D009154:Mutation; D009876:Operon; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000378:metabolism; D012242:Rhodobacter sphaeroides / Q000201:enzymology / Q000235:genetics / Q000254:growth & development*; D012273:Ribulose-Bisphosphate Carboxylase / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism; D014158:Transcription, Genetic; D015854:Up-Regulation
D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D014157:Transcription Factors; C072714:cfxR protein, bacteria; D017853:Phosphotransferases (Alcohol Group Acceptor); C022390:phosphoribulokinase; D012273:Ribulose-Bisphosphate Carboxylase