title: The relationship between myelodysplastic syndromes and autoimmune disorders.
abstract: OBJECTIVE
  To explore the relationship between the myelodysplastic syndromes (MDS) and autoimmune disorders (AID).
  
  
  METHODS
  The clinical data of 117 MDS patients were reviewed.
  
  
  RESULTS
  Nineteen (16.2%) of 117 MDS patients had AIDs. The commonest AID associated with MDS was rheumatoid arthritis (31.6%) and ulcerative colitis (26.3%). Compared with that in MDS patients without autoimmune disorders, the leukemic transformation rate was not increased in the MDS/AID but the median survival time was shorter in MDS/AID patients.
  
  
  CONCLUSIONS
  MDS patients associated with autoimmune disorders may be an unfavorable factor for their prognosis.
authors.affiliation: Department of Hematology, The Second Hospital of Wuhan, Wuhan 430014, China.
authors.forename: Shi
authors.initials: S
authors.lastname: Zhao
authors.forename: Hong
authors.initials: H
authors.lastname: Mao
authors.forename: Hongxiang
authors.initials: H
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Yu
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000293:Adolescent; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications; D001327:Autoimmune Diseases / Q000150:complications*; D003093:Colitis, Ulcerative / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications*; D011237:Predictive Value of Tests