[Effectiveness of mexidol in acute pancreatitis].
Mexidol effectiveness was tried in acute pancreatitis (AP). It was found that in acute pancreatitis mexidol provides a reliable defence of membrane structures, decreased the rate of lipid peroxidation, enhanced the activity of the antioxidative system. This eventually results in reduced number of AP complications (by 9-13%) and mortality (by 7%). In AP mexidol should be injected intraductally.
Ivanov
Iu V
IuV
Chudnykh
S M
SM
Mozgalin
A G
AG
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000681:Amylases / Q000097:blood; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use*; D004796:Clinical Enzyme Tests; D005260:Female; D006801:Humans; D008049:Lipase / Q000097:blood; D015227:Lipid Peroxidation; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D010847:Picolines / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014357:Trypsin / Q000097:blood
D000975:Antioxidants; D010847:Picolines; C070020:emoxypine succinate; D008049:Lipase; D000681:Amylases; D014357:Trypsin