title: Tissue array technique for p53 expression in human ovarian neoplasms.
abstract: OBJECTIVE
  To investigate the expression of p53 in human ovarian neoplasms by tissue array technique.
  
  
  METHODS
  The expression of p53 protein in various ovarian tissues was studied by tissue array and immunohistochemistry.
  
  
  RESULTS
  The expression rate of p53 was 33% in ovarian cancers. There were no expressions in normal ovarian tissues, benign ovarian neoplasms and borderline ovarian neoplasms (P < 0.005). p53 expression was not associated with age of patients and grade of differentiation (P > 0.05) while p53 expression was associated with tissue types (P < 0.05).
  
  
  CONCLUSIONS
  The expression rates of p53 in ovarian cancers were obviously increased.
authors.affiliation: Department of Obstetrics and Gynecology, People's Hospital of Guizhou Province, Guiyang 550002, China.
authors.forename: Yapin
authors.initials: Y
authors.lastname: Wang
authors.forename: He
authors.initials: H
authors.lastname: Wang
authors.forename: Zhilan
authors.initials: Z
authors.lastname: Peng
authors.forename: Kaixuan
authors.initials: K
authors.lastname: Yang
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010051:Ovarian Neoplasms; D016159:Tumor Suppressor Protein p53
chemical_list: D016159:Tumor Suppressor Protein p53