Some biochemical characteristics and water exchange in human articular cartilage in osteoarthrosis.
Rearrangement of intra- and intermolecular bonds in collagen molecule, disaggregation of proteoglycans and their elimination from cartilage involved in osteoarthrosis are responsible for water accumulation and its increased mobility in cartilage.
Nikolaeva
S S
SS
VILAR Research, Training, and Methodological Center of Biomedical Technologies, Moscow.
Roshchina
A A
AA
Zon Chkhol
Kim
K
Bykov
V A
VA
Rebrova
G A
GA
Koroleva
O A
OA
Yakovleva
L V
LV
Abramov
Yu V
YV
Rebrov
L B
LB
D002356:Cartilage / Q000378:metabolism*; D002358:Cartilage, Articular / Q000378:metabolism*; D002850:Chromatography, Gel; D003094:Collagen / Q000378:metabolism; D005269:Femur / Q000378:metabolism; D019791:Guanidine / Q000494:pharmacology; D006801:Humans; D006867:Hydrolases / Q000378:metabolism; D010003:Osteoarthritis / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D014574:Uronic Acids / Q000494:pharmacology; D014867:Water / Q000737:chemistry* / Q000378:metabolism
D011509:Proteoglycans; D014574:Uronic Acids; D014867:Water; D003094:Collagen; D006867:Hydrolases; D019791:Guanidine