title: Some biochemical characteristics and water exchange in human articular cartilage in osteoarthrosis.
abstract: Rearrangement of intra- and intermolecular bonds in collagen molecule, disaggregation of proteoglycans and their elimination from cartilage involved in osteoarthrosis are responsible for water accumulation and its increased mobility in cartilage.
authors.affiliation: VILAR Research, Training, and Methodological Center of Biomedical Technologies, Moscow.
authors.forename: S S
authors.initials: SS
authors.lastname: Nikolaeva
authors.forename: A A
authors.initials: AA
authors.lastname: Roshchina
authors.forename: Kim
authors.initials: K
authors.lastname: Zon Chkhol
authors.forename: V A
authors.initials: VA
authors.lastname: Bykov
authors.forename: G A
authors.initials: GA
authors.lastname: Rebrova
authors.forename: O A
authors.initials: OA
authors.lastname: Koroleva
authors.forename: L V
authors.initials: LV
authors.lastname: Yakovleva
authors.forename: Yu V
authors.initials: YV
authors.lastname: Abramov
authors.forename: L B
authors.initials: LB
authors.lastname: Rebrov
mesh_terms: D002356:Cartilage / Q000378:metabolism*; D002358:Cartilage, Articular / Q000378:metabolism*; D002850:Chromatography, Gel; D003094:Collagen / Q000378:metabolism; D005269:Femur / Q000378:metabolism; D019791:Guanidine / Q000494:pharmacology; D006801:Humans; D006867:Hydrolases / Q000378:metabolism; D010003:Osteoarthritis / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D014574:Uronic Acids / Q000494:pharmacology; D014867:Water / Q000737:chemistry* / Q000378:metabolism
chemical_list: D011509:Proteoglycans; D014574:Uronic Acids; D014867:Water; D003094:Collagen; D006867:Hydrolases; D019791:Guanidine