Pulmonary low-grade MALT-lymphoma associated with localized pulmonary amyloidosis. A case report.
We report on a female patient, who, at the age of 63 years, was found to suffer from low-grade MALT-lymphoma localized at her right upper eyelid. At the time of initial diagnosis, clinical staging showed no further organ involvement. Within the following two months, nodular infiltrates occurred in both lungs. Histopathological investigation of the pulmonary lesions showed pulmonary involvement by the low-grade MALT-lymphoma associated with large globular amyloid deposits of lambda-light chain origin. Since the tumor cells of the MALT-lymphoma showed restriction to lambda-light chain the amyloid deposits in this case were interpreted as being related to the MALT-lymphoma.
Wieker
Katrin
K
Department of Haematology and Oncology, Otto-von-Guericke-University, Magdeburg, Germany.
Röcken
Christoph
C
Koenigsmann
Michael
M
Roessner
Albert
A
Franke
Astrid
A
D000686:Amyloidosis / Q000503:physiopathology*; D000971:Antineoplastic Combined Chemotherapy Protocols; D003520:Cyclophosphamide; D004317:Doxorubicin; D005143:Eyelids / Q000503:physiopathology; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008168:Lung / Q000503:physiopathology; D008175:Lung Neoplasms / Q000188:drug therapy / Q000503:physiopathology*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000188:drug therapy / Q000503:physiopathology*; D008875:Middle Aged; D011241:Prednisone; D014750:Vincristine
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone