Medial prefrontal cortex early lesion effects on classical conditioned bradycardia.
The effects of medial prefrontal cortex early lesion (mPFl) on classical conditioned bradycardia (CB) were studied in adult rabbits. In lesioned rabbits, baseline HR, orienting and conditioned HR responses were similar to controls. Since mPFl alone does not affect CB, while it is known to prevent the HR increments produced by a concomitant early cerebellar vermal ablation, medial prefrontal cortex must be involved in the reorganization of the CB control mechanisms following early cerebellar vermal ablation.
Sebastiani
Laura
L
Dipartimento di Fisiologia e Biochimica, Università di Pisa, via S. Zeno 31, 56127 Pisa, Italy. lauseba@dfb.unipi.it
Ghelarducci
Brunello
B
D000818:Animals; D001919:Bradycardia; D002531:Cerebellum / Q000502:physiology; D003214:Conditioning, Classical; D006339:Heart Rate / Q000502:physiology; D017397:Prefrontal Cortex / Q000293:injuries / Q000502:physiology*; D011817:Rabbits