title: The role of leptin in the control of body weight.
abstract: Physiologic responses to high and low leptin concentrations are strikingly asymmetrical. High concentrations often produce minimal effects, whereas low concentrations provoke strong counterregulatory responses. A model and rationale for the physiology is presented.
authors.affiliation: Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
authors.forename: Rudolph L
authors.initials: RL
authors.lastname: Leibel
mesh_terms: D000818:Animals; D001835:Body Weight / Q000502:physiology*; D004734:Energy Metabolism / Q000502:physiology; D005260:Female; D006801:Humans; D020738:Leptin / Q000502:physiology*; D008297:Male; D051379:Mice; D009765:Obesity / Q000503:physiopathology*
chemical_list: D020738:Leptin