Metabolism of DDT [1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane] by Alcaligenes denitrificans ITRC-4 under aerobic and anaerobic conditions.
An isolated bacterium, Alcaligenes denitrificans ITRC-4, metabolizes 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) under both aerobic and anaerobic conditions. The aerobic metabolism is inhibited by 38% and 47% in the presence of 1.0 g L(-1) of sodium acetate and sodium succinate, respectively, but remains uninhibited in the presence of 1.0 g L(-1) of glucose. Also, the metabolism is inhibited completely in the presence of biphenyl vapors, as well as 0.8 g L(-1) of 2,2'-bipyridyl. Under anaerobic conditions, DDT is metabolized into 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (DDD), which is further enhanced by 50% in the presence of 1.0 g L(-1) of glucose. Besides, the bacterium also metabolizes 4-chlorobenzoate, which is accompanied by the release of chloride ions.
Ahuja
Rajiv
R
Industrial Toxicology Research Centre, Post Box No. 80, M.G. Marg, Lucknow 226 001, India.
Kumar
Ashwani
A
D000332:Aerobiosis; D000421:Alcaligenes / Q000378:metabolism*; D000693:Anaerobiosis; D002723:Chlorobenzoates / Q000378:metabolism; D003634:DDT / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure
D002723:Chlorobenzoates; D003634:DDT