title: Late spontaneous epigastric arterial bleeding associated with abciximab: successful percutaneous treatment with coil gel-foam embolization.
abstract: We describe a case of spontaneous hemorrhage from a branch of the right inferior epigastric artery, unrelated to the access site. This complication occurred in association with the administration of abciximab. Prompt identification of this unusual complication resulted in successful bleeding control using coil and gel-foam embolization. Our purpose is to draw attention to yet another potentially catastrophic adverse side effect of abciximab infusion. To our knowledge, spontaneous rupture of an inferior epigastric artery during abciximab therapy has not been previously reported. In addition, the treatment of such an artery with coil and gel-foam has not been previously described. As with the other described complications, due diligence is required so that spontaneous arterial bleeding can be identified and swift intervention be taken.
authors.affiliation: Good Samiritan Regional Medical Center, Phoenix, AZ, USA.
authors.forename: Madhavagopal
authors.initials: M
authors.lastname: Cherukuri
authors.forename: Ashish
authors.initials: A
authors.lastname: Pershad
mesh_terms: D000077284:Abciximab; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D004621:Embolization, Therapeutic; D019074:Epigastric Arteries; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced* / Q000628:therapy; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000009:adverse effects*; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*
chemical_list: D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D010975:Platelet Aggregation Inhibitors; D000077284:Abciximab