The expression of fibroblast growth factor-2 and fibroblast growth factor receptor-1 in chondrocytes in synovial chondromatosis of the temporomandibular joint. report of two cases.
Synovial chondromatosis (SC) is a rare, benign condition characterized by the formation of metaplastic cartilaginous nodules. The expression of fibroblast growth factor-2 (FGF-2) and fibroblast growth factor receptor-1 (FGFR-1) in two cases of SC of the temporomandibular joint (TMJ) were immunohistochemically studied. The possible roles of FGF-2 and FGFR-1 in SC of the TMJ are discussed.
Sato
J
J
Department of Oral and Maxillofacial Surgery, Kanazawa Medical University, Kahoku-gun, Ishikawa, Japan. jun-s@kanazawa-med.ac.jp
Segami
N
N
Suzuki
T
T
Yoshitake
Y
Y
Nishikawa
K
K
D002356:Cartilage / Q000473:pathology; D019902:Chondrocytes / Q000473:pathology*; D015838:Chondromatosis, Synovial / Q000473:pathology*; D005260:Female; D016222:Fibroblast Growth Factor 2 / Q000032:analysis*; D005500:Follow-Up Studies; D006801:Humans; D006965:Hyperplasia; D007150:Immunohistochemistry; D007594:Joint Loose Bodies / Q000473:pathology; D008335:Mandibular Condyle / Q000473:pathology; D008679:Metaplasia; D008875:Middle Aged; D020794:Receptor Protein-Tyrosine Kinases / Q000032:analysis*; D051496:Receptor, Fibroblast Growth Factor, Type 1; D017468:Receptors, Fibroblast Growth Factor / Q000032:analysis*; D013583:Synovial Membrane / Q000473:pathology; D013705:Temporomandibular Joint Disorders / Q000473:pathology*
D017468:Receptors, Fibroblast Growth Factor; D016222:Fibroblast Growth Factor 2; C496348:FGFR1 protein, human; D020794:Receptor Protein-Tyrosine Kinases; D051496:Receptor, Fibroblast Growth Factor, Type 1