Fibres and colorectal cancer: should we change our dietary advice on prevention?
Evidence from epidemiological studies overwhelmingly indicates that fruit, vegetables and cereals prevent cancer at a wide range of sites in the body, not just the large bowel. However, recent important papers have shown that an intervention diet rich in fruit, vegetables and fibre failed to decrease the risk of new colorectal adenoma formation. The adenoma-cancer sequence and the role of diet are discussed in the light of these new findings.
Giacosa
A
A
Gastroenterology and Nutrition Unit, National Cancer Research Institute, Genoa, Italy. giacosa@hp380.ist.unige.it
Hill
M J
MJ
Davies
G J
GJ
D000236:Adenoma / Q000517:prevention & control*; D015179:Colorectal Neoplasms / Q000517:prevention & control*; D004032:Diet; D004043:Dietary Fiber; D005260:Female; D005638:Fruit; D006801:Humans; D008297:Male; D014675:Vegetables