Studies on the production and regulation of interleukin, IL-13, IL-4 and interferon-gamma in human Schistosomiasis mansoni.
The production and regulation of interleukin (IL) IL-13, IL-4 and interferon-gamma was evaluated in different clinical forms of human schistosomiasis. The mechanisms of immune regulation are apparently different in the various clinical stages of the disease, some of them being antigen specific.
de Morais
Clarice N Lins
CN
Centro de Pesquisas Aggeu Magalhães, Fiocruz, Recife, PE, 50670-420, Brasil.
Rodrigues de Souza
Joelma
J
Gomes de Melo
Wlademir
W
Aroucha
Marcílio L
ML
Domingues
Ana Lúcia C
AL
Wynn
Thomas
T
Abath
Frederico Guilherme Coutinho
FG
Montenegro
Silvia M L
SM
D000208:Acute Disease; D000818:Animals; D000947:Antigens, Helminth; D002908:Chronic Disease; D000949:Histocompatibility Antigens Class II; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis*; D018793:Interleukin-13 / Q000096:biosynthesis*; D015847:Interleukin-4 / Q000096:biosynthesis*; D012555:Schistosomiasis mansoni / Q000276:immunology*
D000947:Antigens, Helminth; D000949:Histocompatibility Antigens Class II; D018793:Interleukin-13; D015847:Interleukin-4; D007371:Interferon-gamma