title: Endoscopic study on cancer of gastric cardia in the high incidence areas of China.
abstract: OBJECTIVE
  Endoscopy was used to study the high incidence area of cancer of gastric cardia.
  
  
  METHODS
  417 patients with early cardiac cancer and 451 patients with advanced lesions were analyzed to the high incidence point of cardiac cancer. Verifying endoscopic screening of 205 subjects was performed later in the high incidence area of esophageal cancer.
  
  
  RESULTS
  327 of 417 (78.4%) of early cardiac cancer patients and 336 of 451 (74.5%) of advanced lesions were proved to have developed their origin at the root of the mucosal fold in the gastric cardia. Eleven cardiac cancer patients were found by the verifying endoscopic screening, among whom 9 patients (81.8%) developed the primary focus at the root of mucosal fold in the cardia.
  
  
  CONCLUSIONS
  The root of mucosal fold in the gastric cardia is proved to be the high incidence point of cancer of gastric cardia, which is very important clinically.
authors.affiliation: Department of Endoscopy, Cancer Institute (Hospital), Chinese Academy of Medical Sciences, Beijing 100021, Department of Endoscopy, Cancer Hospital, Linzhou City, China.
authors.forename: Guoqing
authors.initials: G
authors.lastname: Wang
authors.forename: Changqing
authors.initials: C
authors.lastname: Hao
authors.forename: Shaoqing
authors.initials: S
authors.lastname: Lai
mesh_terms: D002681:China / Q000453:epidemiology; D005773:Gastroscopy / Q000379:methods; D006801:Humans; D015994:Incidence; D013274:Stomach Neoplasms / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*