Trends of multiple-drug resistance among Salmonella serotype Typhi isolates during a 14-year period in Egypt.
A total of 853 isolates of Salmonella serotype Typhi recovered from patients with typhoid fever who were admitted to a major infectious disease hospital in Cairo, Egypt, from 1987 through 2000 underwent antibiotic susceptibility testing to determine multiple-drug resistance. The observed resurgence of chloramphenicol susceptibility (P=.002) may suggest reuse of this drug for the treatment of typhoid fever in Egypt.
Wasfy
Momtaz O
MO
United States Naval Medical Research Unit Number 3, FPO AE 09835-0007, USA. wasfym@namru3.med.navy.mil
Frenck
Robert
R
Ismail
Tharwat F
TF
Mansour
Hoda
H
Malone
Joseph L
JL
Mahoney
Frank J
FJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018432:Drug Resistance, Multiple / Q000502:physiology*; D004534:Egypt; D006801:Humans; D008826:Microbial Sensitivity Tests; D012475:Salmonella / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D014435:Typhoid Fever / Q000382:microbiology*
D000900:Anti-Bacterial Agents