Intrathecal fentanyl added to hyperbaric ropivacaine for cesarean delivery.
OBJECTIVE
Hyperbaric ropivacaine produces adequate spinal anesthesia for cesarean delivery. Addition of opioid to local anesthetics improves spinal anesthesia. We assessed the effect of fentanyl added to hyperbaric ropivacaine for spinal anesthesia for cesarean delivery.


METHODS
Fifty-nine healthy, full-term parturients scheduled for elective cesarean delivery under spinal anesthesia were randomly assigned in a double-blind fashion to receive either fentanyl 10 micro g or normal saline 0.2 mL added to 0.5% hyperbaric ropivacaine 18 mg. Characteristics of spinal block, intraoperative quality of spinal anesthesia, side effects, complete analgesia (time to first feeling of pain), and effective analgesia (time to first request of analgesics) were assessed.


RESULTS
Duration of sensory block was prolonged in the fentanyl group (P <.05). Duration of motor block was similar in both groups. The quality of intraoperative analgesia was better in the fentanyl group (P <.05). Incidence of side effects did not differ between groups. Duration of complete analgesia (143.2 +/- 34.2 minutes v 101.4 +/- 21.4 minutes; P <.001) and effective analgesia (207.2 +/- 32.2 minutes v 136.3 +/- 14.1 minutes; P <.001) were prolonged in the fentanyl group.


CONCLUSIONS
Adding fentanyl 10 micro g to hyperbaric ropivacaine 18 mg for spinal anesthesia for cesarean delivery improves intraoperative anesthesia and increases the analgesia in the early postoperative period.
Chung
Chan Jung
CJ
Department of Anesthesiology, College of Medicine, Dong-A Universit, Busan, Korea. cjchung@daunet.donga.ac.kr
Yun
Sung Hun
SH
Hwang
Gi Baeg
GB
Park
Jung Sil
JS
Chin
Young Jhoon
YJ
D000328:Adult; D000577:Amides / Q000008:administration & dosage*; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002585:Cesarean Section; D004311:Double-Blind Method; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage*; D006801:Humans; D010149:Postoperative Pain / Q000517:prevention & control; D011247:Pregnancy; D000077212:Ropivacaine; D016896:Treatment Outcome
D000577:Amides; D000701:Analgesics, Opioid; D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D000077212:Ropivacaine; D005283:Fentanyl