title: Intrarenal neuroblastoma diagnosed by fine-needle aspiration: a report of two cases.
abstract: Neuroblastoma is an infrequent tumor of childhood usually located at any site containing sympathetic neural tissue-retroperitoneum and adrenal gland being the most common locations, followed by thoracopulmonary region, mediastinum, head and neck, and pelvis. Two primary renal neuroblastomas were diagnosed in a 6-yr-old boy and a 7-mo-old boy by computed tomography (CT)-guided fine-needle aspiration (FNA) cytology. The smears contained numerous individually scattered small and round cells, with scanty cytoplasm, related to a fibrillary matrix. Scattered larger cells with slightly more cytoplasm were seen among the smaller ones. No tubular or glomeruloid differentiation was noted. Considering the age and cytomorphology, a diagnosis of intrarenal neuroblastoma was made in both cases. An intrarenal mass in a child may occasionally be a neuroblastoma. Our cases demonstrate the usefulness of CT-guided FNA in diagnosing intrarenal masses in children.
authors.affiliation: Department of Pathology and Radiology, Hospital Doce de Octubre, Madrid, Spain.
authors.forename: Rosario
authors.initials: R
authors.lastname: Serrano
authors.forename: José Luis
authors.initials: JL
authors.lastname: Rodríguez-Peralto
authors.forename: Gabino G
authors.initials: GG
authors.lastname: De Orbe
authors.forename: Carmen
authors.initials: C
authors.lastname: Melero
authors.forename: Pedro
authors.initials: P
authors.lastname: de Agustín
mesh_terms: D001707:Biopsy, Needle; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary; D002648:Child; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D009447:Neuroblastoma / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D009396:Wilms Tumor / Q000473:pathology