title: Trends of multiple-drug resistance among Salmonella serotype Typhi isolates during a 14-year period in Egypt.
abstract: A total of 853 isolates of Salmonella serotype Typhi recovered from patients with typhoid fever who were admitted to a major infectious disease hospital in Cairo, Egypt, from 1987 through 2000 underwent antibiotic susceptibility testing to determine multiple-drug resistance. The observed resurgence of chloramphenicol susceptibility (P=.002) may suggest reuse of this drug for the treatment of typhoid fever in Egypt.
authors.affiliation: United States Naval Medical Research Unit Number 3, FPO AE 09835-0007, USA. wasfym@namru3.med.navy.mil
authors.forename: Momtaz O
authors.initials: MO
authors.lastname: Wasfy
authors.forename: Robert
authors.initials: R
authors.lastname: Frenck
authors.forename: Tharwat F
authors.initials: TF
authors.lastname: Ismail
authors.forename: Hoda
authors.initials: H
authors.lastname: Mansour
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Malone
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Mahoney
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018432:Drug Resistance, Multiple / Q000502:physiology*; D004534:Egypt; D006801:Humans; D008826:Microbial Sensitivity Tests; D012475:Salmonella / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D014435:Typhoid Fever / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents