title: Compactibility study of calcium phosphate biomaterials.
abstract: This study investigated the micromechanism responsible for the densification and consolidation of powders during dynamic compaction, an experimental process in which ceramic is formed without heating. Three calcium-deficient apatites (CDA: two powders and a fibrous compound) and a biphasic calcium phosphate (BCP) were studied to determine their aptitude (rheological and physical properties) for compactibility under various dynamic compaction pressures. Powders were investigated for their physicochemistry, particle size, and flow time, and compacts for their compaction rate, density, specific area, mechanical characteristics, and disintegration time. Powder particles showed different morphological features depending on the synthesis protocol used, specific area and rheological behaviour. Compacts were not obtained with BCP, regardless of the gas pressure used, whereas CDA produced compacts with good mechanical properties (high hardness and compression stress), particularly for the fibrous compound. The poor compressibility and compactibility of BCP powders were confirmed, whereas fibrous CDA powders showed good compactibility conducive to high-quality filling of biomaterials.
authors.affiliation: Laboratoire de Mécanique des Solides et des Matériaux FORSEM, Institut Universitaire de Technologie de Nantes, 3 rue du Maréchal Joffre, BP 34103, 44041 Nantes Cedex 1, France.
authors.forename: C
authors.initials: C
authors.lastname: Nicolazo
authors.forename: H
authors.initials: H
authors.lastname: Gautier
authors.forename: M-J
authors.initials: MJ
authors.lastname: Brandao
authors.forename: G
authors.initials: G
authors.lastname: Daculsi
authors.forename: C
authors.initials: C
authors.lastname: Merle
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D012212:Rheology; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous