title: [Sino-nasal endoscopic surgery in fungal sinusitis. Our experience].
abstract: Fungal sinusitis is a rare entity which has increased amongst immunocompromised individuals. Records of thirteen patients treated of fungal sinus disease between 1995 and 2001 were reviewed. Histopathological studies demonstrated infection due to Aspergillus in eight patients and due to Mucormycosis in five patients. The surgical debridement via endoscopic sinus surgery was the essential part of the management. The follow-up is 12-72 months (mean 29.08). The main clinical findings and a review of the literature are presented. We conclude that endoscopic sinus surgery is the treatment of choice for fungal sinusitis except in advanced cases of mucormycosis in which a combined approach is still necessary together with intravenous antifungal drugs (amphotericin B).
authors.affiliation: Unidad de Rinología, Servicio de Otorrinolaringología, Hospital Clínic, C/Villarroel, 170, 08036 Barcelona. 32874iao@comb.es
authors.forename: I
authors.initials: I
authors.lastname: Alobid
authors.forename: M
authors.initials: M
authors.lastname: Bernal
authors.forename: L M
authors.initials: LM
authors.lastname: Menéndez
authors.forename: L
authors.initials: L
authors.lastname: Alós
authors.forename: P
authors.initials: P
authors.lastname: Benítez
authors.forename: A
authors.initials: A
authors.lastname: Cardesa
authors.forename: J
authors.initials: J
authors.lastname: Mullol
mesh_terms: D000328:Adult; D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery*; D003646:Debridement / Q000379:methods*; D004724:Endoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery*; D013517:Otorhinolaryngologic Surgical Procedures; D012189:Retrospective Studies; D012233:Rhizopus; D012852:Sinusitis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery*; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B