[A case of postoperative liver metastasis from gastric cancer which responded well to weekly chemotherapy with paclitaxel].
We report a case of postoperative liver metastasis from gastric cancer showing a remarkable response to weekly administration of paclitaxel (TXL). The patient was a 50-year-old woman who underwent total gastrectomy. One month later, liver metastasis and a small amount of ascites were detected by CT scan. Therefore, the patient was administered weekly TXL. TXL (80 mg/m2) was infused over 1 hour after short premedication on an outpatient basis. Administration was continued for 3 weeks followed by 1 week rest. Liver metastasis and ascites disappeared 3 months after administration. The toxic events were leukopenia (grade 1) and alopecia (grade 1). No major adverse effects were observed.
Yamamoto
Daigo
D
Dept. of Surgery, Seiko Hospital.
Hamada
Yoshinori
Y
Yamamoto
Chizuko
C
Inoue
Kentaro
K
Yamamoto
Mitsuo
M
D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage*; D011184:Postoperative Period; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery
D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel