Complete remission induced by high dose erythropoietin and granulocyte colony stimulating factor in acute erythroleukemia (AML-M6 with maturation).
Alternative therapeutic approaches with low dose chemotherapy and differentiative-maturative treatment by growth factors are under consideration for elderly patients with acute leukemia. Two patients with AML-M6 with maturation, one refractory to standard chemotherapy and the other ineligible for cytoxic treatment, obtained complete remission from leukemia using high dose recombinant erythropoietin and granulocyte colony-stimulating factor.
Camera
Andrea
A
Volpicelli
Mario
M
Villa
Maria Rosaria
MR
Risitano
Antonio M
AM
Rossi
Marco
M
Rotoli
Bruno
B
D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D004921:Erythropoietin / Q000008:administration & dosage*; D017809:Fatal Outcome; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage*; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000188:drug therapy*; D008297:Male; D012074:Remission Induction / Q000379:methods
D004921:Erythropoietin; D016179:Granulocyte Colony-Stimulating Factor