Function of the alternative oxidase: is it still a scavenger?
The alternative oxidase is a respiratory chain protein found in all higher plants, fungi, non-fermentative yeasts and trypanosomes. Its primary structure suggests that it is a new member of the di-iron carboxylate protein family. Recent sequence analysis indicates an evolutionary relationship between primitive members of this protein family and the alternative oxidase, suggesting that its early function was to scavenge di-oxygen. However, modelling of plant growth kinetics suggests a different function.
Moore
Anthony L
AL
School of Biological Sciences, University of Sussex, Falmer, Brighton, UK BN1 9QG. a.l.moore@sussex.ac.uk
Albury
Mary S
MS
Crichton
Paul G
PG
Affourtit
Charles
C
D004579:Electron Transport / Q000502:physiology; D019143:Evolution, Molecular; D016166:Free Radical Scavengers / Q000378:metabolism*; D024101:Mitochondrial Proteins; D010088:Oxidoreductases / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D010802:Phylogeny; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D000099188:Alternative Oxidase
D016166:Free Radical Scavengers; D024101:Mitochondrial Proteins; D010088:Oxidoreductases; D010940:Plant Proteins; D000099188:Alternative Oxidase