title: Histopathologic classification of 3 476 orbital diseases.
abstract: OBJECTIVE
  To investigate the histopathologic classification and distribution of orbital diseases.
  
  
  METHODS
  The authors analyzed 3 476 orbital diseases examined in 1976 - 2000 in the pathology laboratory.
  
  
  RESULTS
  Benign orbital diseases were 81.90%. The 10 leading benign orbital diseases were cavernous hemangioma (515), vascular leiomyoma (364), inflammatory pseudotumor (347), dermoid (230), schwannoma (183), meningioma (150), benign mixed tumor of the lacrimal gland (147), mucocele (141), varix (132) and neurofibroma (76). Malignant orbital tumors were 18.10%. The numbers of malignant tnmors were malignant lacrimal gland epithelial tumors (129, 20.51%), rhabdomyosarcoma (75), non-Hodgkin's disease (65), secondary to nasosinus carcinoma (51), metastatic tumor (50), chloroma (32), extraocular extension of retinoblastoma (26) and extraocular extension of choroid malanoma (23).
  
  
  CONCLUSIONS
  The vascular tumors and malformations are commonly seen in orbital diseases. The primary malignant tumor in the orbit is the malignant lacrimal gland epithelial tumors.
authors.affiliation: Department of Ophthalmology, Tianjin Medical University, Tianjin 300211, China (Email: h_yanjin@263.net)
authors.forename: Yanjin
authors.initials: Y
authors.lastname: He
authors.forename: Guoxiang
authors.initials: G
authors.lastname: Song
authors.forename: Ying
authors.initials: Y
authors.lastname: Ding
mesh_terms: D005134:Eye Neoplasms; D006392:Hemangioma, Cavernous; D006801:Humans; D008577:Meningeal Neoplasms; D009916:Orbital Diseases; D009918:Orbital Neoplasms