Quinacrine-induced psychiatric disturbances in a child with common variable immunodeficiency and chronic giardiasis.
Psychiatric disorders due to quinacrine for antiparasitic therapy represent an infrequent, but serious, complication. The remarkable course of a 12-year-old boy with common variable immunodeficiency who developed severe psychiatric reactions following quinacrine therapy for his resistant chronic giardiasis is presented. The broad clinical spectrum of quinacrine-associated neuropsychiatric disturbances has been emphasized for the clinicians.
Genel
Ferah
F
Department of Pediatrics, Ege University, The Medical School, Izmir, Turkey. ferahgen@yahoo.com
Erermis
Serpil
S
Aksu
Guzide
G
Ozturk
Can
C
Kutukculer
Necil
N
D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000009:adverse effects* / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001569:Benzodiazepines; D002648:Child; D002908:Chronic Disease; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000469:parasitology / Q000523:psychology; D004351:Drug Resistance; D005873:Giardiasis / Q000150:complications* / Q000469:parasitology / Q000523:psychology; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011605:Psychoses, Substance-Induced / Q000523:psychology*; D011796:Quinacrine / Q000009:adverse effects* / Q000627:therapeutic use
D014151:Anti-Anxiety Agents; D000981:Antiprotozoal Agents; D014150:Antipsychotic Agents; D001569:Benzodiazepines; D011796:Quinacrine; D006220:Haloperidol