The efficacy of simvastatin is not influenced by CYP2D6 polymorphism.
Geisel
Jürgen
J
Kivistö
Kari T
KT
Griese
Ernst-Ulrich
EU
Eichelbaum
Michel
M
D000483:Alleles; D000924:Anticholesteremic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D019821:Simvastatin / Q000009:adverse effects / Q000627:therapeutic use*
D000924:Anticholesteremic Agents; D019821:Simvastatin; D019389:Cytochrome P-450 CYP2D6