title: Situation analysis of atypical squamous cells of undetermined significance smears in Songklanagarind Hospital.
abstract: OBJECTIVE
  To review the incidence, management, follow-up rate and colposcopic diagnosis of atypical squamous cells of undetermined significance (ASCUS) detected on cervical smears in Songklanagarind Hospital, Thailand.
  
  
  METHODS
  A retrospective study of ASCUS smears taken during January 2000 to March 2001 at Songklanagarind Hospital was performed. The type of management was classified and the follow-up rate was detected. Cases with colposcopy, tissue biopsy, endocervical curettage, conization and hysterectomy specimen were reviewed. In the cases without tissue biopsy, the final diagnoses were based on the colposcopic examination.
  
  
  RESULTS
  Among the 25068 Pap smears examined, the incidence of ASCUS was 0.62%. Of these, only 56.13% received the further evaluation. The non-compliance rate was 18.71%. The incidences of cervical intraepithelial neoplasia (CIN) and invasive cancer among the cases who received colposcopy were 15.96% and 2.13%, respectively. The incidence of CIN or invasive cancer in ASCUS favor reactive and ASCUS favor neoplasia were not different statistically significant.
  
  
  CONCLUSIONS
  Management of ASCUS smears by follow-up may be inappropriate. A practice guideline which consists of active management, intensive follow-up system and well-organized data management should be used to improve the situation.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Hat-Yai, Thailand. csaibua@ratree.psu.ac.th
authors.forename: Saibua B
authors.initials: SB
authors.lastname: Chichareon
authors.forename: Sathana T
authors.initials: ST
authors.lastname: Tocharoenvanich
mesh_terms: D000328:Adult; D003127:Colposcopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D018307:Neoplasms, Squamous Cell / Q000473:pathology*; D065006:Papanicolaou Test; D012189:Retrospective Studies; D013785:Thailand; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears