Protein origami for beginners.
In the October issue of Molecular Cell, Kowarik et al. examine cotranslational translocation and folding during the synthesis of secretory and integral membrane proteins. Their results suggest that these potentially competing processes are regulated in surprising ways and reveal novel insights into the mechanisms by which proteins are assembled into membranes.
Andrews
David W
DW
Department of Biochemistry, McMaster University, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada.
D002462:Cell Membrane / Q000378:metabolism; D008958:Models, Molecular; D014176:Protein Biosynthesis; D017510:Protein Folding; D021381:Protein Transport; D011506:Proteins / Q000378:metabolism
D011506:Proteins