title: [Primary carcinoma of the subglottic larynx].
abstract: OBJECTIVE
  Primary carcinoma of the subglottic larynx is very rare. This study was designed to evaluate patients who were treated for primary carcinoma of the subglottic larynx.
  
  
  METHODS
  The study included 15 patients (14 men, 1 woman; mean age 62.8 years; range 45 to 95 years) with primary subglottic carcinoma. Correlations of different clinical parameters with three-year survival rate and Kaplan-Meier survival analysis were investigated.
  
  
  RESULTS
  On presentation, two patients (14%) had T1, five patients (33%) had T2, three patients (20%) had T3, and five patients (33%) had T4 tumors. The overall three-year survival rate was 73.4% (11/15). The median survival calculated by the Kaplan-Meier method was 45 months. No significant differences were found between the survival rates of patients with and without extralaryngeal extension.
  
  
  CONCLUSIONS
  Although primary subglottic cancer is locally aggressive with high tendency to extend to the extralaryngeal compartment at the time of diagnosis, high survival rates can be expected when appropriate treatment modalities are selected.
authors.affiliation: Department of Otolaryngology, Medicine Faculty of Istanbul University, Turkey. erdamar@e-kolay.net
authors.forename: Burak
authors.initials: B
authors.lastname: Erdamar
authors.forename: Yusufhan
authors.initials: Y
authors.lastname: Süoğlu
authors.forename: A Haluk H
authors.initials: AH
authors.lastname: Emin
authors.forename: Kamil
authors.initials: K
authors.lastname: Akdağ
authors.forename: Erkan
authors.initials: E
authors.lastname: Kiyak
authors.forename: Tayfun
authors.initials: T
authors.lastname: Sunay
authors.forename: Ismail
authors.initials: I
authors.lastname: Cölhan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D016019:Survival Analysis; D016896:Treatment Outcome