title: Poxvirus Orthologous Clusters (POCs).
abstract: Poxvirus Orthologous Clusters (POCs) is a JAVA client-server application which accesses an updated database containing all complete poxvirus genomes; it automatically groups orthologous genes into families based on BLASTP scores for assessment by a human database curator. POCs has a user-friendly interface permitting complex SQL queries to retrieve interesting groups of DNA and protein sequences as well as gene families for subsequent interrogation by a variety of integrated tools: BLASTP, BLASTX, TBLASTN, Jalview (multiple alignment), Dotlet (Dotplot), Laj (local alignment), and NAP (nucleotide to amino acid alignment).
authors.affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC V8W 3P6, Canada.
authors.forename: Angelika
authors.initials: A
authors.lastname: Ehlers
authors.forename: John
authors.initials: J
authors.lastname: Osborne
authors.forename: Stephanie
authors.initials: S
authors.lastname: Slack
authors.forename: Rachel L
authors.initials: RL
authors.lastname: Roper
authors.forename: Chris
authors.initials: C
authors.lastname: Upton
mesh_terms: D016000:Cluster Analysis; D004279:DNA, Viral / Q000145:classification / Q000235:genetics; D003628:Database Management Systems; D030541:Databases, Genetic; D004282:Documentation / Q000379:methods; D016679:Genome, Viral; D020407:Internet; D019212:Multimedia; D011212:Poxviridae / Q000145:classification* / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods; D012984:Software; D014584:User-Computer Interface
chemical_list: D004279:DNA, Viral