title: Outcome after endovascular therapy of ruptured intracranial aneurysms: morbidity and impact of rebleeding.
abstract: We evaluated midterm functional outcome after endovascular occlusion of aneurysms in patients with subarachnoid haemorrhage (SAH) and determined the incidence of late rebleeding as an additional prognostic parameter. We treated 79 consecutive patients with SAH from an intracranial aneurysm admitted from a neurological intensive care unit by the endovascular route between 1993 and 1997 and 52 survivors were followed up in 1999-2000. The mean interval between SAH and follow-up was 41 months (range 13-74 months). Outcome was determined by the Glasgow outcome (GOS) and Rankin (RS) scales and by questions concerning neuropsychological disorders. The patients were analysed according to Hunt and Hess (H & H) grades I-III or IV-V on admission. We observed two episodes of rebleeding (3%) with impact on outcome at 907 and 2010 days after SAH, respectively. A complete recovery (GOS 5) was achieved in 53% of H & H grade I-III and 17% of grade IV-V patients; with death rates 19% and 50%, and morbidity according to the RS (5-2) 18% and 29%, respectively. Midterm morbidity after endovascular therapy is thus low. Rebleeding with an impact on outcome can be observed up to 2010 days after SAH, suggesting that long-term angiographic follow-up is indispensable.
authors.affiliation: Department of Neurology, University Hospital Hamburg, Friedrich-Ebert Krankenhaus Neumünster, Germany. christine.kremer@nos.usz.ch
authors.forename: C
authors.initials: C
authors.lastname: Kremer
authors.forename: C
authors.initials: C
authors.lastname: Groden
authors.forename: G
authors.initials: G
authors.lastname: Lammers
authors.forename: G
authors.initials: G
authors.lastname: Weineck
authors.forename: H
authors.initials: H
authors.lastname: Zeumer
authors.forename: H C
authors.initials: HC
authors.lastname: Hansen
mesh_terms: D000328:Adult; D017542:Aneurysm, Ruptured / Q000150:complications / Q000401:mortality / Q000628:therapy*; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013345:Subarachnoid Hemorrhage / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D016019:Survival Analysis; D016896:Treatment Outcome