title: [Benign metastasizing pulmonary leiomyoma: description of a case and review of the literature].
abstract: We report the case of a 48-year-old woman with multiple benign metastasizing leiomyomas in both lungs and a single retroperitoneal leiomyoma. The patient underwent surgical resection of the lesions 15 years after total hysterectomy for uterine myomas. Immunohistochemical studies performed on the retroperitoneal and pulmonary neoplasms showed them to be of mesenchymal derivation with smooth muscle differentiation; the samples were negative for HMB-45. Some histogenetic hypotheses for the multiple leiomyomas are presented.
authors.affiliation: U.O. Anatomia Patologica e Citodiagnostica, Polo Oncologico Regina Elena, Via Elio Chianesi 53, I-00144 Roma, Italia.
authors.forename: S
authors.initials: S
authors.lastname: Sentinelli
authors.forename: R
authors.initials: R
authors.lastname: Covello
authors.forename: M
authors.initials: M
authors.lastname: Benevolo
authors.forename: S
authors.initials: S
authors.lastname: Licci
authors.forename: R
authors.initials: R
authors.lastname: Perrone Donnorso
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007889:Leiomyoma / Q000601:surgery; D018231:Leiomyomatosis / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000737:chemistry / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D058950:Melanoma-Specific Antigens; D008648:Mesoderm / Q000473:pathology; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis; D012186:Retroperitoneal Neoplasms / Q000737:chemistry / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins