title: Resection for cancers of the pancreatic head in patients aged 70 years or over.
abstract: OBJECTIVE
  To find out if resections of cancers of the head of pancreatic are justified in patients over the age of 70 years.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  University hospital, Germany.
  
  
  METHODS
  519 patients with cancers of the pancreatic head, 93 (18%) of whom were aged 70 or over.
  
  
  METHODS
  Comparison of outcomes between those aged 70 or over, and those aged less than 70.
  
  
  RESULTS
  There were 247 ductal adenocarcinomas, 134 carcinomas of the papilla of Vater, 79 carcinomas of the distal common bile duct, and 59 miscellaneous tumours. Of all variables compared (age, sex, symptoms, operations, clinical and pathological stage. morbidity, mortality, and long-term survival) the only significant difference between the groups was that leaks from the pancreaticojejunostomy occured more often in the older age group (p = 0.02). However, this did not influence overall morbidity or mortality.
  
  
  CONCLUSIONS
  Patients' age is not a limiting factor in attempts at curative resection of cancers of the head of pancreas. If the tumour is resectable and patient is motivated and well enough, resection is indicated whatever the age.
authors.affiliation: Department of Surgery, University-Hospital Mannheim, University of Heidelberg, Germany.
authors.forename: Axel
authors.initials: A
authors.lastname: Richter
authors.forename: Marco
authors.initials: M
authors.lastname: Niedergethmann
authors.forename: Dietmar
authors.initials: D
authors.lastname: Lorenz
authors.forename: Jörg W
authors.initials: JW
authors.lastname: Sturm
authors.forename: Michael
authors.initials: M
authors.lastname: Trede
authors.forename: Stefan
authors.initials: S
authors.lastname: Post
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater; D021441:Carcinoma, Pancreatic Ductal / Q000473:pathology / Q000601:surgery; D003138:Common Bile Duct Neoplasms / Q000401:mortality / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018579:Patient Selection; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome