title: [Algebraic 2D PET image reconstruction using depth-of-interaction information]
abstract: Recently a high-performance PET scanner, which measures depth-of-interaction (DOI) information, is being developed for molecular imaging. DOI measurement of multi-layered thin crystals can improve spatial resolution and scanner sensitivity simultaneously. In this paper, we apply an algebraic image reconstruction method to 2-dimensional (2D) DOI-PET scanners using accurate system modeling, in order to evaluate the effects of using DOI information on PET image quality. Algebraic image reconstruction methods have been successfully used to improve PET image quality, compared with the conventional filtered backprojection method. The proposed method is applied to simulated data for a small 2D DOI-PET scanner. The results show that accurate system modeling improves spatial resolution without noise emphasis, and that DOI information improves uniformity of spatial resolution.
authors.affiliation: Imaging Science and Engineering Laboratory, Tokyo Institute of Technology. isl.titech.ac.jp.
authors.forename: Taiga
authors.initials: T
authors.lastname: Yamaya
authors.forename: Takashi
authors.initials: T
authors.lastname: Obi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: Kouichi
authors.initials: K
authors.lastname: Kita
authors.forename: Nagaaki
authors.initials: N
authors.lastname: Ohyama
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Hideaki
authors.initials: H
authors.lastname: Haneishi
authors.forename: Hideo
authors.initials: H
authors.lastname: Murayama