title: Chiral separation of thiazide diuretics by HPLC on Chiralcel OD-RH, Chiralcel OJ-R and Chirobiotic-T phases.
abstract: This contribution deals with comparative studies on the chiral separation of thiazide diuretics using cellulose tris(3,5-dimethylphenylcarbamate) (Chiralcel OD-RH), cellulose tris(4-methylbenzoate) (Chiralcel OJ-R) and teicoplanin (Chirobiotic T) phases. All columns showed good chiral recognition ability for this class of compounds. Out of seven compounds investigated, six were resolved with baseline resolution with at least one of the three columns.
authors.affiliation: Central Research Laboratory, Faculty of Medicine, University of Pécs, Szigeti út 12, H-7643 Pécs, Hungary.
authors.forename: Balázs
authors.initials: B
authors.lastname: Visegrády
authors.forename: Tünde
authors.initials: T
authors.lastname: Konecsni
authors.forename: Nina
authors.initials: N
authors.lastname: Grobuschek
authors.forename: Martin G
authors.initials: MG
authors.lastname: Schmid
authors.forename: Ferenc
authors.initials: F
authors.lastname: Kilár
authors.forename: Hassan Y
authors.initials: HY
authors.lastname: Aboul-Enein
authors.forename: Gerald
authors.initials: G
authors.lastname: Gübitz
mesh_terms: D001565:Benzoates; D001581:Benzothiadiazines; D002219:Carbamates; D002482:Cellulose / Q000031:analogs & derivatives*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D004232:Diuretics; D004867:Equipment Design; D048448:Phenylcarbamates; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D049993:Sodium Chloride Symporter Inhibitors / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism; D017334:Teicoplanin
chemical_list: D001565:Benzoates; D001581:Benzothiadiazines; D002219:Carbamates; D004232:Diuretics; D048448:Phenylcarbamates; D049993:Sodium Chloride Symporter Inhibitors; C090722:tris(4-methylbenzoate)cellulose; C079151:cellulose trisphenylcarbamate; D017334:Teicoplanin; D002482:Cellulose