Congenital chondrodysplastic dwarfism with dyshematopoiesis in a holstein calf.
A holstein calf with congenital chondrodysplastic dwarfism was histopathologically examined. The head of the calf was relatively flat giving a dog-like appearance with its short nose and sloping forehead. Limb bones were dumbbell-like with short diaphysis and hypertrophied metaphyses. Bone marrow was pale, whitish and fatty. In the metaphyseal plates most of chondrocytes were pyknotic with swollen and ghost-like cytoplasm, and were irregularly arranged. Column of calcified cartilage were poorly formed losing comb-like structure. Bone marrow was ischemic with poor hematopoiesis and was moderately replaced by adipose tissue. In articular cartilage, most of chondrocytes were degenerated with ghost-like cytoplasm. Many cartilage canals and occasional bone marrow-like structure were formed. The characteristics lesions of the calf were chondrodysplasia and dyshematopoiesis.
Naito
Kazumi
K
Yamanashi Eastern Livestock Hygiene Center, Higashiyatsushiro-gun, Yamanashi, Japan.
Maruyama
Minoru
M
Dobashi
Koji
K
Tanimura
Nobuhiko
N
Kimura
Kumiko
K
Haritani
Makoto
M
Nakajima
Yasuyuki
Y
D000818:Animals; D001853:Bone Marrow / Q000002:abnormalities / Q000473:pathology; D001842:Bone and Bones / Q000002:abnormalities / Q000473:pathology; D002417:Cattle / Q000002:abnormalities*; D002418:Cattle Diseases / Q000151:congenital* / Q000473:pathology; D019902:Chondrocytes / Q000473:pathology; D004392:Dwarfism / Q000151:congenital* / Q000662:veterinary*; D005260:Female; D017880:Limb Deformities, Congenital / Q000473:pathology / Q000662:veterinary; D010009:Osteochondrodysplasias / Q000151:congenital* / Q000473:pathology / Q000662:veterinary*