title: [Cytokeratin expression in the epithelial cells of nasal polyp].
abstract: OBJECTIVE
  To study the expression of cytokeratin in epithelial cells of nasal polyp and its significance.
  
  
  METHODS
  The monoclonal antibody of AE1, AE3, CK7, CK14, CK19, CK20 were used to determined the corresponding cytokeratin expression in epithelial cells of nasal polyp with immunohistochemical staining.
  
  
  RESULTS
  1. AE1, CK7, CK19 staining were positive in various pathological epithelium of nasal polyp. AE1, CK19 showed positive in total layer of epithelium. CK7 was positive in goblet cells and basal cells of the pseudostratified epithelium. 2. AE3, CK20 staining were positive in part of simple epithelium and stratified epithelium. 3. AE1, AE3, CK7, CK19 staining showed focal positive in transitional epithelium.
  
  
  CONCLUSIONS
  CK7, CK19 are the one of the essential assembly type of cytokeratin in epithelium of nasal polyp. During the process of inflammatory reaction, the expression of partial cytokeratin subtype would lose while a new cytokeratin pattern would appear.
authors.affiliation: Department of Otolaryngology, Nanping Second Hospital, Jianyang 354200.
authors.forename: Mingying
authors.initials: M
authors.lastname: Zhuo
authors.forename: Jun
authors.initials: J
authors.lastname: Yang
authors.forename: Feng
authors.initials: F
authors.lastname: Yang
authors.forename: Xing
authors.initials: X
authors.lastname: Lin
mesh_terms: D004847:Epithelial Cells / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D053552:Keratin-7; D007633:Keratins / Q000096:biosynthesis*; D009298:Nasal Polyps / Q000378:metabolism* / Q000473:pathology
chemical_list: C507497:KRT7 protein, human; D053552:Keratin-7; D007633:Keratins