A mild and selective method for cleavage of O-acetyl groups with dibutyltin oxide.
A mild and efficient neutral method for the cleavage of O-acetyl groups with dibutyltin oxide has been developed. This method is especially useful in the synthesis of glycosides containing base- or acid-sensitive multifunctional groups.
Liu
Hong-Min
HM
Department of Chemistry, Zhengzhou University, Daxue Road, Zhengzhou 450052, PR China. liuhm@zzu.edu.cn
Yan
Xuebin
X
Li
Wen
W
Huang
Conghai
C
D000107:Acetylation; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009947:Organotin Compounds / Q000737:chemistry*; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
D006027:Glycosides; D009947:Organotin Compounds; C031078:dibutyltin oxide