When ligand becomes receptor--tolerance via B7 signaling on DCs.
Finger
Erik B
EB
Bluestone
Jeffrey A
JA
D000069594:Abatacept; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics / Q000276:immunology*; D018122:B7-1 Antigen / Q000187:drug effects / Q000276:immunology*; D018106:CD28 Antigens / Q000276:immunology; D060908:CTLA-4 Antigen; D003602:Cytotoxicity, Immunologic; D003713:Dendritic Cells / Q000276:immunology*; D004790:Enzyme Induction; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology*; D018796:Immunoconjugates / Q000235:genetics / Q000494:pharmacology*; D007371:Interferon-gamma / Q000378:metabolism; D008024:Ligands; D008213:Lymphocyte Activation / Q000276:immunology*; D051379:Mice; D008822:Mice, Transgenic; D018448:Models, Immunological; D011993:Recombinant Fusion Proteins / Q000276:immunology / Q000494:pharmacology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D014366:Tryptophan Oxygenase / Q000502:physiology
D015703:Antigens, CD; D000943:Antigens, Differentiation; D018122:B7-1 Antigen; D018106:CD28 Antigens; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D008024:Ligands; D011993:Recombinant Fusion Proteins; D000069594:Abatacept; D007371:Interferon-gamma; D014366:Tryptophan Oxygenase