title: The genome of Brucella melitensis.
abstract: The genome of Brucella melitensis strain 16M was sequenced and contained 3,294,931 bp distributed over two circular chromosomes. Chromosome I was composed of 2,117,144 bp and chromosome II has 1,177,787 bp. A total of 3,198 ORFs were predicted. The origins of replication of the chromosomes are similar to each other and to those of other alpha-proteobacteria. Housekeeping genes such as those that encode for DNA replication, protein synthesis, core metabolism, and cell-wall biosynthesis were found on both chromosomes. Genes encoding adhesins, invasins, and hemolysins were also identified.
authors.affiliation: Institute of Molecular Biology and Medicine, University of Scranton, Scranton, PA 18510, USA. vimbm@aol.com
authors.forename: Vito G
authors.initials: VG
authors.lastname: DelVecchio
authors.forename: Vinayak
authors.initials: V
authors.lastname: Kapatral
authors.forename: Philip
authors.initials: P
authors.lastname: Elzer
authors.forename: Guy
authors.initials: G
authors.lastname: Patra
authors.forename: Cesar V
authors.initials: CV
authors.lastname: Mujer
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D017347:Brucella melitensis / Q000235:genetics*; D016680:Genome, Bacterial; D006360:Heat-Shock Proteins / Q000235:genetics; D016366:Open Reading Frames
chemical_list: D001426:Bacterial Proteins; D006360:Heat-Shock Proteins