title: [Functional changes and structural features of the testis in patients after acute parotid orchitis].
abstract: Structural changes and functional features of the testes were studied in 20 patients who had had parotid orchitis (PO) 6 months to 1.5 years before the study. The examination including ultrasonography of the testes, investigation of ejaculate, radioimmunoassay for serum testosterone, FSH, LH brought out a significant reduction of the mean volume and echogenicity of the affected testicles by 44.7 and 50%, respectively, in 15 patients; a 58.2% decrease in the number of spermatozoa in ml; a 71.2% rise in FSH level in 6 patients. Morphometry of biopsy specimen of the testicles on the affected side has shown that mean sectional area of the tubules has diminished by 40%, the spermatogenesis index--by 77.1% while the volume of the intertubular connective tissue increased by 47.7%. Thus, after acute PO, the patients develop atrophic changes in the testes and a decline in spermatogenic function up to secretory infertility.
authors.forename: A A
authors.initials: AA
authors.lastname: Solov'ev
authors.forename: A F
authors.initials: AF
authors.lastname: Astrakhantsev
authors.forename: V G
authors.initials: VG
authors.lastname: Aristarkhov
authors.forename: V F
authors.initials: VF
authors.lastname: Siniakov
mesh_terms: D000208:Acute Disease; D000328:Adult; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009107:Mumps / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D009920:Orchitis / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D011863:Radioimmunoassay; D013091:Spermatogenesis; D013737:Testis / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology*; D013739:Testosterone / Q000097:blood; D014463:Ultrasonography
chemical_list: D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone