Remission of lymphoma after drug withdrawal in rheumatoid arthritis.
A 63-year-old man with rheumatoid arthritis presented with pain and swelling of his right buttock. Imaging and tissue biopsy revealed a diffuse large B-cell, non-Hodgkin's lymphoma. The disease-modifying drugs he was taking, cyclosporin and methotrexate, were stopped, and the lymphoma resolved spontaneously without the use of chemotherapy.
Lim
Irwin G S
IG
Department of Rheumatology, Royal North Shore Hospital, St Leonards, NSW, Australia.
Bertouch
James V
JV
D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy*; D002081:Buttocks; D016572:Cyclosporine / Q000008:administration & dosage* / Q000009:adverse effects; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000150:complications / Q000473:pathology; D018482:Muscle, Skeletal / Q000473:pathology; D012075:Remission, Spontaneous
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D008727:Methotrexate