title: Butenafine: an update of its use in superficial mycoses.
abstract: Butenafine is a synthetic benzylamine antifungal agent that may be fungicidal against susceptible organisms, e.g., dermatophytes. Butenafine may be effective and safe in the treatment of interdigital tinea pedis (apply twice daily for 1 week or once daily for 4 weeks), tinea corporis/tinea cruris (apply twice daily for 2 weeks), and pityriasis versicolor (apply once daily for 2 weeks). The effectiveness of the drug persists for at least 4 weeks following the discontinuation of therapy suggesting that there is some retention of the drug in the skin following termination of active therapy.
authors.affiliation: Division of Dermatology, Department of Medicine, Sunnybrook and Womens' College Health Sciences Center (Sunnybrook Site), University of Toronto, Toronto, Ontario, Canada.
authors.forename: A K
authors.initials: AK
authors.lastname: Gupta
mesh_terms: D000287:Administration, Topical; D000935:Antifungal Agents / Q000627:therapeutic use*; D001596:Benzylamines / Q000627:therapeutic use*; D006801:Humans; D009281:Naphthalenes / Q000627:therapeutic use*; D014005:Tinea / Q000188:drug therapy*; D014010:Tinea Versicolor / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents; D001596:Benzylamines; D009281:Naphthalenes; C067594:butenafine