title: [Diagnostic value of ultrasound-guided anastomotic biopsies in patients with high PSA (> or = 0,4 ng/ml) after radical prostatectomy].
abstract: OBJECTIVE
  The authors report their experience on the use of a high number of biopsies for the diagnosis of a vesicourethral anastomosis tumor recurrence in patients who underwent radical prostatectomy with a PSA elevation.
  
  
  METHODS
  Sixty-five patients with PSA > or = 0.4 ng/ml after radical prostatectomy received 6 to 8 transrectal ultrasound (TRUS) guided biopsies of the vesicourethral anastomosis.
  
  
  RESULTS
  The biopsy scheme with 6 random anastomotic biopsies plus additional biopsies through TRUS detectable lesions was able to diagnose a local recurrence in more than 60% of the cases. In presence of a post-operative PSA < 1.0 ng/ml and in absence of ultrasound detectable or palpable lesions a local neoplastic recurrence was detected in 58% of the cases. In presence of a palpable or ultrasound visible lesions, the detection rate increases to 80% of the cases.
authors.affiliation: Dipartimento di Urologia, Istituto Scientifico Ospedale San Raffaele, Milano, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Scattoni
authors.forename: Marco
authors.initials: M
authors.lastname: Roscigno
authors.forename: Marco
authors.initials: M
authors.lastname: Raber
authors.forename: Francesco
authors.initials: F
authors.lastname: Montorsi
authors.forename: Roberto
authors.initials: R
authors.lastname: Bertini
authors.forename: Lina
authors.initials: L
authors.lastname: Bua
authors.forename: Luigi
authors.initials: L
authors.lastname: Da Pozzo
authors.forename: Patrizio
authors.initials: P
authors.lastname: Rigatti
mesh_terms: D001706:Biopsy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D014463:Ultrasonography
chemical_list: D017430:Prostate-Specific Antigen