Viral interactions with receptors in cell junctions and effects on junctional stability.
Several viruses can use, as entry receptors, cell adhesion molecules that localize to junctional complexes of epithelial cells and other cell types. A recent publication in Cell describes how adenovirus can disrupt cell junctions, thereby effecting its release from basal surfaces of an infected epithelium to the apical or external environment.
Spear
Patricia G
PG
Department of Microbiology-Immunology, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology; D006801:Humans; D007365:Intercellular Junctions / Q000502:physiology / Q000821:virology*; D011991:Receptors, Virus / Q000502:physiology*; D014779:Virus Replication / Q000502:physiology*
D015815:Cell Adhesion Molecules; D011991:Receptors, Virus