Management of gigantomastia complicating pregnancy. A case report.
BACKGROUND
Gigantomastia during pregnancy is exceedingly rare, with an incidence of 1/28,000-100,000 pregnancies. Treatment during pregnancy is a dilemma, and postpartum reduction mammoplasty remains the mainstay of treatment.


METHODS
Massive bilateral breast enlargement occurred at 19 weeks of gestation in a 24-year-old woman, gravida 2, and led to ulceration and sloughing. Conservative management with bromocriptine resulted in healing of the ulcers and resolution of symptoms. After six months of bromocriptine therapy postpartum, marked involution of the breasts occurred without recurrence.


CONCLUSIONS
Prolonged bromocriptine therapy should be given after delivery to a pregnant woman with gigantomastia during pregnancy before planning surgical reduction mammoplasty.
Agarwal
Nutan
N
Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India. nutan_agarwal@hotmail.com
Kriplani
Alka
A
Gupta
Anjali
A
Bhatla
Neerja
N
D000328:Adult; D001940:Breast / Q000473:pathology*; D001971:Bromocriptine / Q000627:therapeutic use*; D002585:Cesarean Section; D005260:Female; D006727:Hormone Antagonists / Q000627:therapeutic use*; D006801:Humans; D006984:Hypertrophy; D016462:Mammaplasty; D011181:Postnatal Care / Q000379:methods; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000473:pathology*; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods*; D011388:Prolactin / Q000037:antagonists & inhibitors*; D012883:Skin Ulcer / Q000209:etiology
D006727:Hormone Antagonists; D001971:Bromocriptine; D011388:Prolactin