title: Manometric abnormality in dysphagic patients after medullary cerebrovascular accidents.
abstract: We investigated the pharyngeal swallowing function using videomanofluorometry (VMF) in patients after medullary cerebrovascular accidents. Upper esophageal sphincter pressure, which should drop when a bolus arrives at the hypopharynx, increased at the same time as the elevation of oropharyngeal and hypopharyngeal pressures. A reduction of oropharyngeal and hypopharyngeal swallowing pressures was also observed. Our results suggest that a misprogrammed excitatory output from the central pattern generators of the brain stem would cause an abnormal pressure-traveling pattern of pharyngeal swallowing. VMF was useful to assess the pharyngeal swallowing function and to determine the indications for cricopharyngeal myotomy for patients after medullary cerebrovascular accidents.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, 3-1 Hongo 7-chome, Bunkyo-ku, Tokyo 113-8655, Japan. rhigo-tky@umin.ac.jp
authors.forename: Ryuzaburo
authors.initials: R
authors.lastname: Higo
authors.forename: Niro
authors.initials: N
authors.lastname: Tayama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Watanabe
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003680:Deglutition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D008297:Male; D008365:Manometry; D008526:Medulla Oblongata; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D020521:Stroke / Q000150:complications*; D014741:Video Recording