title: Outcome of pregnancies after non-amniocentesis-induced premature rupture of membranes at 14 to 23 weeks' gestation.
abstract: OBJECTIVE
  To evaluate the outcome of singleton pregnancies after non-amniocentesis-induced premature rupture of membranes (PROM) at 14 to 23 weeks' gestation.
  
  
  METHODS
  We reviewed the hospital records of 53 consecutive pregnant women with PROM at 14 to 23 weeks' gestation at our institution from 1991 to 1996; the pregnancies were not associated with amniocentesis or multiple gestation.
  
  
  RESULTS
  The median interval between PROM and delivery was 1 day (range 0-90; mean 5.2 days). Fifty-two (98%) of the 53 neonates were stillborn or died within 4 days. One neonate (2%), a 720-gram male delivered vaginally at 23 weeks' gestation, survived. The infant had Apgar scores of 6 at 1 minute and 2 at 5 minutes, and showed normal physical and neurological development at age 5 months.
  
  
  CONCLUSIONS
  The outcome of pregnancies with non-amniocentesis-induced PROM at 14 to 23 weeks' gestation is almost uniformly poor.
authors.affiliation: Department of Obstetrics and Gynecology, University of Graz, Austria. scholzhs@kfunigraz.ac.at
authors.forename: Heinz S
authors.initials: HS
authors.lastname: Scholz
authors.forename: M Gürkan
authors.initials: MG
authors.lastname: Arikan
authors.forename: Christoph
authors.initials: C
authors.lastname: Benedicic
authors.forename: Edgar
authors.initials: E
authors.lastname: Petru
authors.forename: Josef
authors.initials: J
authors.lastname: Haas
authors.forename: Peter A M
authors.initials: PA
authors.lastname: Weiss
mesh_terms: D000649:Amniocentesis; D001317:Austria; D002821:Chorioamnionitis / Q000401:mortality / Q000473:pathology; D005260:Female; D005313:Fetal Death / Q000453:epidemiology* / Q000473:pathology; D005322:Premature Rupture of Fetal Membranes / Q000401:mortality* / Q000473:pathology; D005328:Fetal Viability; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011262:Pregnancy Trimester, Second; D012189:Retrospective Studies; D016019:Survival Analysis