title: Pelvic Castleman disease presenting as vaginal occlusion.
abstract: BACKGROUND
  Castleman disease is a lymphoreticular disorder, which may be clinically silent. However, systemic manifestations can occur, which include generalized adenopathy and life-threatening bronchiolitis obliterans.
  
  
  METHODS
  A woman presented with vaginal mucosal lesions recalcitrant to initial treatment efforts. Progression of the disease required hospitalization for pulmonary involvement. Castleman disease was diagnosed after extensive multidisciplinary evaluation and excision of a pelvic mass. The patient's symptoms dramatically improved postoperatively.
  
  
  CONCLUSIONS
  Castleman disease should be included in the differential diagnosis in patients with paraneoplastic symptoms and a pelvic mass.
authors.affiliation: Section of Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: Glenn A
authors.initials: GA
authors.lastname: Gaunt
authors.forename: Bobbie S
authors.initials: BS
authors.lastname: Gostout
authors.forename: Ellen
authors.initials: E
authors.lastname: Remstein
authors.forename: William A
authors.initials: WA
authors.lastname: Cliby
mesh_terms: D005871:Castleman Disease / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D012131:Respiratory Insufficiency / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014623:Vaginal Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery