title: MR colonography: development of optimized method with ex vivo and in vivo systems.
abstract: An ex vivo magnetic resonance (MR) colonographic system with a bovine colon with polyps of predetermined dimensions was developed for evaluation and optimization of different combinations of imaging sequences and intraluminal contrast agents. Findings were then applied during in vivo testing in human subjects. The results show that optimized contrast and lesion conspicuity and minimized motion artifacts can be obtained with true fast imaging with steady-state precession combined with water as an intraluminal contrast agent.
authors.affiliation: Department of Abdominal Imaging, West Virginia University School of Medicine, Robert C. Byrd Health Sciences Center, PO Box 9235, Morgantown, WV 26505-9235, USA. dmartin@hsc.wvu.edu
authors.forename: Diego R
authors.initials: DR
authors.lastname: Martin
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
authors.forename: David
authors.initials: D
authors.lastname: Thomasson
authors.forename: Craig
authors.initials: C
authors.lastname: Acheson
mesh_terms: D000285:Administration, Rectal; D000328:Adult; D000818:Animals; D002417:Cattle; D003106:Colon / Q000473:pathology*; D003111:Colonic Polyps / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D019047:Phantoms, Imaging; D012016:Reference Values
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA