title: Direct determination of absolute configuration of monoalcohols by bis(magnesium porphyrin).
abstract: Ethane bridged bis(Mg porphyrin) has been found to be an effective sensor for the direct determination of the absolute configuration of a variety of monoalcohols at millimolar concentrations and room temperature based on the CD exciton chirality method. Examination of a variety of synthetic and natural monoalcohols, including alpha-substituted aliphatic and aromatic alkanols with one chiral center, as well as alicyclic alcohols with 2-5 chiral centers, gave consistent results. In the case of alcohols with multiple chiral centers, the absolute configuration of the carbon alpha to OH is always read out.
authors.affiliation: Entropy Control Project, ICORP, JST, 4-6-3 Kamishinden, Toyonaka 560-0085, Japan. lintuluo@kuchem.kyoto-u.ac.jp
authors.forename: Juha M
authors.initials: JM
authors.lastname: Lintuluoto
authors.forename: Victor V
authors.initials: VV
authors.lastname: Borovkov
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Inoue