Ardisiphenols and other antioxidant principles from the fruits of Ardisia colorata.
Novel alkylphenols, ardisiphenols A-C (1-3) and a novel bergenin derivative, demethoxybergenin (10) were isolated from the fruits of Ardisia colorata (Myrsinaceae), together with known alkylresorcinols (4-6), embelin (7), myricetin (8), quercetin (9), bergenin (11), norbergenin (12), kaempferol (13), quercetin-3-O-beta-D-glucopyranoside (14) and gallic acid (15). Their structures were determined by NMR, MS(/MS) analyses and other spectroscopic methods. Ardisiphenols showed moderate scavenging activities toward 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and showed cytotoxicity against the murine breast cancer cell line, FM3A.
Sumino
Megumi
M
Graduate School of Pharmaceutical Sciences, Chiba University, Japan.
Sekine
Toshikazu
T
Ruangrungsi
Nijsiri
N
Igarashi
Kazuei
K
Ikegami
Fumio
F
D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification; D031644:Ardisia / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D012118:Resorcinols / Q000737:chemistry* / Q000302:isolation & purification
D000975:Antioxidants; D010936:Plant Extracts; D012118:Resorcinols; C454672:ardisiphenol A; C454673:ardisiphenol B; C454674:ardisiphenol C