title: Acute isolated bulbar palsy with anti-GT1a IgG antibody subsequent to Campylobacter jejuni enteritis.
abstract: We describe a patient with acute isolated bulbar palsy following enteritis. A 29-year-old man developed dysphagia and nasal voice without limb weakness, ataxia, or areflexia. High titres of serum anti-GT1a and anti-Campylobacter jejuni IgG antibodies were detected. He was treated with plasmapheresis, resulting in rapid clinical improvement. This case suggests that an acute isolated bulbar palsy may be caused by a pathology relating to Guillain-Barré syndrome (GBS), in which anti-GT1a IgG antibody may have a role.
authors.affiliation: Department of Neurology, Chiba Rosai Hospital, Chiba, Japan.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Onodera
authors.forename: Masahiro
authors.initials: M
authors.lastname: Mori
authors.forename: Michiaki
authors.initials: M
authors.lastname: Koga
authors.forename: Ikuo
authors.initials: I
authors.lastname: Kamitsukasa
authors.forename: Toshio
authors.initials: T
authors.lastname: Fukutake
authors.forename: Takamichi
authors.initials: T
authors.lastname: Hattori
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Yuki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kuwabara
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D010244:Bulbar Palsy, Progressive / Q000097:blood / Q000150:complications / Q000276:immunology*; D002169:Campylobacter Infections / Q000150:complications / Q000276:immunology*; D016123:Campylobacter jejuni / Q000276:immunology*; D004751:Enteritis / Q000150:complications / Q000276:immunology*; D005732:Gangliosides / Q000276:immunology*; D020275:Guillain-Barre Syndrome / Q000150:complications; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis / Q000276:immunology*; D008297:Male; D010956:Plasmapheresis
chemical_list: D001323:Autoantibodies; D005732:Gangliosides; D007074:Immunoglobulin G; C016481:trisialoganglioside GT1