title: Six-month follow-up of takotsubo cardiomyopathy with I-123-beta-metyl-iodophenyl pentadecanoic acid and I-123-meta-iodobenzyl-guanidine myocardial scintigraphy.
abstract: A 69-year-old man with a history of transient chest pain was diagnosed takotsubo cardiomyopathy. In I-123-beta-metyl-iodophenyl pentadecanoic acid myocardial scintigraphy, decreased uptake of apex was seen in the acute phase, and it recovered in 3 months. In I-123-meta-iodobenzyl-guanidine myocardial scintigraphy, decreased uptake of apex persisted for 6 months, and there was a discrepancy between apical and total washout rate in the acute phase and after 3 months, which disappeared after 6 months. We speculate that the discrepancy of sympathetic innervation between the apical and basal region is the cause of the characteristic left ventricular apical akinesia of takotsubo cardiomyopathy.
authors.affiliation: Department of Cardiology, The Japanese Red Cross Nagasaki Atomic Bomb Hospital.
authors.forename: Manabu
authors.initials: M
authors.lastname: Moriya
authors.forename: Hideki
authors.initials: H
authors.lastname: Mori
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Suzuki
authors.forename: Minoru
authors.initials: M
authors.lastname: Hazama
authors.forename: Katsusuke
authors.initials: K
authors.lastname: Yano
mesh_terms: D019797:3-Iodobenzylguanidine; D000368:Aged; D009202:Cardiomyopathies / Q000000981:diagnostic imaging*; D004562:Electrocardiography; D005227:Fatty Acids; D006321:Heart / Q000294:innervation; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013564:Sympathetic Nervous System / Q000000981:diagnostic imaging; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*
chemical_list: D005227:Fatty Acids; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019275:Radiopharmaceuticals; C049338:iodofiltic acid; D019797:3-Iodobenzylguanidine