Anti-stress and anti-fatigue effect of fermented rice bran.
The anti-stress and anti-fatigue effects of a hot water extract of fermented rice bran (FRB) were investigated with Saccharomyces cerevisae IFO 2346 on rats or mice. Oral administration (1 g/kg/day) of a hot water extract of FRB inhibited major changes in weight of the adrenal, thymus, spleen and thyroid, showing the anti-stress effect. A hot water extract of FRB also inhibited the increase of GPT and LDH activity, cholesterol and serum glucose levels. Administration (1 g/kg/day) for 2 weeks significantly prolonged the swimming time, resulting in an increase of the anti-fatigue effect. From these results, it can be considered that FRB has an anti-stress and anti-fatigue effect.
Kim
K M
KM
School of Food Biotechnology, Woosong University, Daejeon 300-718, Korea.
Yu
K W
KW
Kang
D H
DH
Suh
H J
HJ
D000284:Administration, Oral; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D005221:Fatigue / Q000517:prevention & control; D005285:Fermentation; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009929:Organ Size; D012275:Oryza; D005082:Physical Exertion / Q000187:drug effects*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017207:Rats, Sprague-Dawley; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D013312:Stress, Physiological / Q000517:prevention & control; D013550:Swimming
D001786:Blood Glucose; D010936:Plant Extracts; D002784:Cholesterol; D007770:L-Lactate Dehydrogenase