title: Decrease in bispectral index preceding intraoperative hemodynamic crisis: evidence of acute alteration of propofol pharmacokinetics.
authors.affiliation: Department of Anaesthesia, Intensive Care and Pain Medicine, St. Vincent's University Hospital, Dublin, Ireland. honan@iol.ie
authors.forename: David M
authors.initials: DM
authors.lastname: Honan
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Breen
authors.forename: John F
authors.initials: JF
authors.lastname: Boylan
authors.forename: Neil J
authors.initials: NJ
authors.lastname: McDonald
authors.forename: Talmage D
authors.initials: TD
authors.lastname: Egan
mesh_terms: D000368:Aged; D000771:Anesthesia, Intravenous; D004569:Electroencephalography / Q000187:drug effects*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006470:Hemorrhage / Q000378:metabolism*; D006801:Humans; D007431:Intraoperative Complications / Q000503:physiopathology*; D015742:Propofol / Q000493:pharmacokinetics* / Q000494:pharmacology
chemical_list: D015742:Propofol