A new pregnane glycoside and a furostanol glycoside from Digitalis cariensis.
Chemical investigation of the aerial parts of Digitalis cariensis Boiss. ex Jaub. & Spach resulted in the isolation of a new pregnane glycoside, cariensisoside (1) and a furostanol glycoside, uttroside A (2), along with the two known phenylethanoid glycosides, lugrandoside (3) and maxoside (4). On the basis of spectral (UV, IR, NMR, MS) and chemical methods, compounds 1 and 2 were identified as digifologenin-3-O-beta-glucopyranosyl-(1-->4)-beta-oleandropyranoside and 3-O-(beta-lycotetraosyl)-26-O-(beta-glucopyranosyl)-(25R)-22 alpha-methoxy-5-furostane-3 beta,26-diol, respectively.
Kirmizibekmez
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H
Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Taşdemir
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D
Ersöz
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T
Ireland
C M
CM
Caliş
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I
D000107:Acetylation; D001713:Biphenyl Compounds; D002240:Carbohydrate Sequence; D002855:Chromatography, Thin Layer; D004070:Digitalis / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010084:Oxidation-Reduction; D010851:Picrates; D011278:Pregnanes / Q000737:chemistry* / Q000302:isolation & purification; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013261:Sterols / Q000737:chemistry* / Q000302:isolation & purification
D001713:Biphenyl Compounds; D006027:Glycosides; D010851:Picrates; D011278:Pregnanes; D013261:Sterols; C468970:cariensisoside; C468969:uttroside A; C004931:1,1-diphenyl-2-picrylhydrazyl