Vacuolation in T-tubules as a model for tubular-vesicular transformations in biomembrane systems.
This review outlines the basic properties of T-tubules in skeletal muscle cells, and the factors that govern reversible vacuolation in T-tubules under experimental conditions. Comparable membranous transformations, involving the plasma membrane or occurring intracellularly, in non-muscle cells are then considered. Finally, the mechanisms of similar transformations in various model membrane systems are discussed. In view of the similarities between reversible vacuolation in the T-system and membrane transformations occurring in a variety of non-muscle cells, it is suggested that reversible vacuolation in T-tubules may be regarded as a general model for tubular-vesicular transformations in biomembranes.
Krolenko
Sergei A
SA
Institute of Cytology, Russian Academy of Sciences, 194064, St Petersburg, Russia.
Lucy
Jack A
JA
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism / Q000648:ultrastructure; D022162:Cytoplasmic Vesicles / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism* / Q000648:ultrastructure; D008954:Models, Biological; D032342:Muscle Cells / Q000378:metabolism* / Q000648:ultrastructure; D018482:Muscle, Skeletal / Q000378:metabolism* / Q000648:ultrastructure; D015388:Organelles / Q000378:metabolism / Q000648:ultrastructure; D014617:Vacuoles / Q000378:metabolism* / Q000648:ultrastructure