title: [A case of large-cell lung cancer with liver metastasis successfully treated using combination chemotherapy with CDDP and vinorelbine].
abstract: A 38-year-old woman presented to our hospital with the chief complaint of dyspnea. A chest radiograph showed pleural effusion of the right lung and a CT scan revealed liver metastasis. A tumor biopsy done under bronchoscopy revealed large-cell carcinoma of the lungs. She was given 4 courses of a combination therapy consisting of CDDP (80 mg/m2) and vinorelbine (25 mg/m2). The primary tumor in the right lung and liver metastasis were markedly reduced in size and a partial response was obtained. The combination therapy of CDDP and vinorelbine may become a standard chemotherapy for advanced non-small cell lung cancer.
authors.affiliation: Dept. of Hematology and Oncology Medicine, Shinnittetu Muroran General Hospital.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Katsuki
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kitaoka
authors.forename: Kouhei
authors.initials: K
authors.lastname: Takizawa
authors.forename: Takuro
authors.initials: T
authors.lastname: Machida
authors.forename: Takaomi
authors.initials: T
authors.lastname: Oku
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Sumiyoshi
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Nagamachi
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Inomata
authors.forename: Shuichi
authors.initials: S
authors.lastname: Nojiri
authors.forename: Masahiko
authors.initials: M
authors.lastname: Nishino
authors.forename: Miri
authors.initials: M
authors.lastname: Fujita
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Niitsu
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018287:Carcinoma, Large Cell / Q000188:drug therapy* / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014747:Vinblastine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D000077235:Vinorelbine
chemical_list: D014747:Vinblastine; D002945:Cisplatin; D000077235:Vinorelbine