Synthesis, structural characterization and antimicrobial studies of hydrazone derivatives of 3-hydroxyimino-5-methyl-2-hexanone.
The derivatives of 3-hydroxyimino-5-methyl-2-hexanone oxime have been obtained in good yield by its reactions either with hydrazine hydrate or phenyl hydrazine, respectively. IR and 1H NMR spectral data of these compounds have been discussed. All the newly synthesised compounds have been tested for their biological activity against S. auerus, S. typhi, C. albicans, A. niger, S. cerevisiae and M. tuberculosis H47RV.
Donde
Kamini J
KJ
Department of Chemistry, The Institute of Science, Mumbai, India.
Patil
Vishwanath R
VR
Utekar
Shilpa S
SS
Malve
Sheela P
SP
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006588:Hexanones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006835:Hydrazones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000706:statistics & numerical data; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D006588:Hexanones; D006835:Hydrazones; D010091:Oximes