Experimental study of reparative regeneration processes in the wound treated with bioactive dressings.
Quantitative and structural functional analysis of granulation tissue cells during treatment with protein-polysaccharide dressing Collahit F was carried out. The preparation effectively cleansed the wound from detritus, prevented secondary infection due to stimulation of the functional activity of macrophages and due to the effect of its antiseptic component (furagin), and stimulated proliferative activity of fibroblasts and granulation tissue microvessels on day 5 of treatment, thus promoting repair processes in the wound.
Chekmareva
I A
IA
Department of Pathological Anatomy, A. V. Vishnevskii Institute of Surgery, Russian Academy of Medical Sciences, Moscow.
D000818:Animals; D001684:Biological Dressings; D005347:Fibroblasts / Q000378:metabolism / Q000648:ultrastructure; D006097:Granulation Tissue / Q000378:metabolism / Q000648:ultrastructure; D008264:Macrophages / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D051381:Rats; D014945:Wound Healing / Q000502:physiology*