The effects of an instant haw beverage on lipid levels, antioxidant enzyme and immune function in hyperlipidemia patients.
OBJECTIVE
To determine the effectiveness of an instant haw beverage in regulating lipid disturbance, enhancing antioxidant enzyme activity and immune function.


METHODS
Data was collected from 60 hyperlipidemic subjects. In this crossover design, each subject randomly received either the instant haw beverage (100 ml corresponding to 3 g of haw powder or 30 g of fresh haw fruit plus the carrier-guar gum plus some starch) or placebo (guar gum 1.5 g plus some starch as the carrier of the beverage) twice daily. Each supplementation lasted 31 days with a 28-day washout period between treatments.


RESULTS
The instant haw beverage significantly reduced total serum cholesterol (9.6%), triglyceride (12.1%), LDLC (18%) while significantly increased SOD activities (7.5%). The placebo was shown to have positive results in some of the lipid profiles, though the effects of the instant haw beverage demonstrated greater significance. Serum triglyceride levels were significantly decreased and SOD activity significantly increased only as subjects were supplemented with the instant haw beverage while no significant changes were seen with placebo.


CONCLUSIONS
Supplementation with the instant haw beverage positively affects blood lipid profile, antioxidant status and immune function in individuals with hyperlipidemia.
Chen
Jidi
J
Institute of Sports Medicine, The Third Hospital, Peking University, Beijing 100083, China.
Xue
Bin
B
Li
Keji
K
Shi
Jingda
J
Krempin
D
D
Zhu
M
M
Garland
C
C
D033942:Adaptor Proteins, Vesicular Transport; D000328:Adult; D000368:Aged; D000975:Antioxidants; D016632:Apolipoprotein A-I / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D001628:Beverages; D002784:Cholesterol / Q000097:blood; D018592:Cross-Over Studies; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011506:Proteins / Q000032:analysis; D013482:Superoxide Dismutase / Q000097:blood*; D014280:Triglycerides / Q000097:blood
D033942:Adaptor Proteins, Vesicular Transport; D000975:Antioxidants; D016632:Apolipoprotein A-I; D001055:Apolipoproteins B; D004365:Drugs, Chinese Herbal; D008055:Lipids; D011506:Proteins; D014280:Triglycerides; C090202:COG2 protein, human; D002784:Cholesterol; D013482:Superoxide Dismutase