title: [Pulmonary carcinosarcoma with jejunal metastasis: complete response to chemotherapy].
abstract: We report a case of pulmonary carcinosarcoma with jejunal metastasis. The lung is an exceptional localization for carcinosarcoma, a tumor with carcinomatous and sarcomatous components. These two components are closely related but well-defined morphologically and immunohistochemically. Risk of metastasis and local recurrence is high. Surgery is the treatment of choice for localized forms. Prognosis depends on the sarcomatous component which is usually sensitive to chemotherapy, with at least doxorubicin and ifosfamide. This rare case illustrates the potential for jejunal metastasis and complete response to chemotherapy, proven histologically at 33 months.
authors.affiliation: Département de Médecine Adulte, Institut Gustave-Roussy, rue Camille-Desmoulins, 94805 Villejuif Cedex, France. saint-georges.francoise@ghic1.fupl.asso.fr
authors.forename: F
authors.initials: F
authors.lastname: Saint-Georges
authors.forename: Ph
authors.initials: P
authors.lastname: Terrier
authors.forename: J C
authors.initials: JC
authors.lastname: Sabourin
authors.forename: S
authors.initials: S
authors.lastname: Bonvalot
authors.forename: V
authors.initials: V
authors.lastname: De Montpreville
authors.forename: P
authors.initials: P
authors.lastname: Ruffie
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002296:Carcinosarcoma / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D007580:Jejunal Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary; D008175:Lung Neoplasms; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D004317:Doxorubicin; D002945:Cisplatin; D007069:Ifosfamide