title: Serum fructosamine concentrations in dogs with hypothyroidism.
abstract: Serum fructosamine concentrations were measured in 11 untreated hypothyroid dogs with normal serum glucose and serum protein concentrations. The fructosamine level ranged between 276 and 441 micromol/L (median 376 micromol/L; reference range 207-340 micromol/L). Nine of the 11 dogs had fructosamine levels above the reference range. The fructosamine levels decreased significantly during treatment with levothyroxine. It is suggested that serum fructosamine concentrations may be high in hypothyroid dogs because of decelerated protein turnover, independent of the blood glucose concentration.
authors.affiliation: Clinic for Small Animal Internal Medicine, University of Zurich, Switzerland.
authors.forename: C E
authors.initials: CE
authors.lastname: Reusch
authors.forename: B
authors.initials: B
authors.lastname: Gerber
authors.forename: F S
authors.initials: FS
authors.lastname: Boretti
mesh_terms: D000375:Aging; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D004283:Dog Diseases / Q000097:blood* / Q000188:drug therapy; D004285:Dogs / Q000097:blood* / Q000145:classification; D005260:Female; D019270:Fructosamine / Q000097:blood*; D007037:Hypothyroidism / Q000097:blood* / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D012016:Reference Values; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D001786:Blood Glucose; D019270:Fructosamine; D013974:Thyroxine