Protein-lipid interactions in the purple bacterial reaction centre.
The purple bacterial reaction centre uses the energy of sunlight to power energy-requiring reactions such as the synthesis of ATP. During the last 20 years, a combination of X-ray crystallography, spectroscopy and mutagenesis has provided a detailed insight into the mechanism of light energy transduction in the bacterial reaction centre. In recent years, structural techniques including X-ray crystallography and neutron scattering have also been used to examine the environment of the reaction centre. This mini-review focuses on recent studies of the surface of the reaction centre, and briefly discusses the importance of the specific protein-lipid interactions that have been resolved for integral membrane proteins.
Jones
Michael R
MR
Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, Bristol, UK. m.r.jones@bristol.ac.uk
Fyfe
Paul K
PK
Roszak
Aleksander W
AW
Isaacs
Neil W
NW
Cogdell
Richard J
RJ
D002308:Cardiolipins / Q000737:chemistry; D018360:Crystallography, X-Ray; D008563:Membrane Lipids / Q000737:chemistry*; D008565:Membrane Proteins / Q000737:chemistry*; D008958:Models, Molecular; D009154:Mutation; D010714:Phosphatidylethanolamines / Q000737:chemistry; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D017433:Protein Structure, Secondary; D012242:Rhodobacter sphaeroides / Q000737:chemistry*; D012241:Rhodopseudomonas / Q000737:chemistry
D002308:Cardiolipins; D008563:Membrane Lipids; D008565:Membrane Proteins; D010714:Phosphatidylethanolamines; D045322:Photosynthetic Reaction Center Complex Proteins