Partial molecular characterization of Sm8, a tegumental antigen of Schistosoma mansoni.
Sm8 is a major tegumental antigen of Schistosoma mansoni. The partial cDNA was isolated and analyzed. Sequence analysis revealed transmembrane compatible hydrophobic domains and a putative leucine zipper pattern. The mRNA and the protein are predominantly expressed in adult worms.
Abath
Frederico G C
FG
Centro de Pesquisas Aggeu Magalhães, Fiocruz, Recife, PE, 50670-420, Brasil.
Xavier
Edeneide M
EM
Montenegro
Sílvia M L
SM
Werkhauser
Roberto P
RP
D000595:Amino Acid Sequence; D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis* / Q000235:genetics; D001483:Base Sequence; D015153:Blotting, Western; D002135:Calcium-Binding Proteins / Q000737:chemistry* / Q000235:genetics; D018076:DNA, Complementary / Q000032:analysis; D015801:Helminth Proteins / Q000737:chemistry* / Q000235:genetics; D008969:Molecular Sequence Data; D012550:Schistosoma mansoni / Q000276:immunology*
D000947:Antigens, Helminth; D002135:Calcium-Binding Proteins; D018076:DNA, Complementary; D015801:Helminth Proteins; C088042:Sm8 protein, Schistosoma mansoni