A practical approach to neutrophil disorders.
This review discusses disorders of altered neutrophil number and function and provide a basic framework for patient evaluation and management. The sections begin with neutropenia, neutrophilia and neutrophil dysfunction with a general screening approach to differentiate common, more benign syndromes from rare, often more serious disorders. Also included is a detailed discussion of some specific primary neutrophil syndromes at the end of each section. Focus is placed on specific disorders that are clinically common or particularly instructive.
Kyono
Wade
W
Division of Pediatric Hematology-Oncology, University of Hawaii John A. Burns School of Medicine, Kapiolani Medical Center, Honolulu 96826, USA. kyono@hawaii.edu
Coates
Thomas D
TD
D006801:Humans; D007960:Leukocyte Disorders / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy; D009504:Neutrophils / Q000502:physiology*