title: Benefits of a mobile, point-of-care anticoagulation therapy management program.
abstract: BACKGROUND
  Current guidelines recommend anticoagulation therapy for a number of medical conditions, but this therapy also has the potential for serious complications, particularly bleeding complications. Maintenance of anticoagulation within a narrow therapeutic window usually entails frequent monitoring with a blood test called the international normalized ratio (INR). Anticoagulation therapy management (ATM) clinics lead to improvements in quality of care, in terms of improved INR control and reduced complications. This study examined the impact of a mobile multisite, office-based ATM program that operated in seven cardiology offices in all three counties in Delaware. ATM PROGRAM: The ATM program was managed by a trained nurse who rotated among all seven offices. Patients made office visits to the nurse and received patient education, point-of-care INR testing, and medication adjustment based on a physician-approved algorithm.
  
  
  METHODS
  This retrospective cohort study compared INR levels in the year before (May 1998-Apr 1999) and the year after (Aug 1999-Jul 2000) the start of the ATM program.
  
  
  RESULTS
  From the year before to the year after implementation of the ATM program, the percentage of in-range INRs increased from 40.7% to 58.5% (p < 0.001). The percentage in the modified target range also increased (50.0% to 62.9%, p < 0.001).
  
  
  CONCLUSIONS
  This study demonstrates the positive impact of a statewide office-based ATM program. If similar programs could be implemented in other networks of specialty offices or primary care offices, they could have a significant benefit to quality of care for patients who require anticoagulation therapy.
authors.affiliation: Christiana Care Health Services, 1401 Foulk Road, Wilmington, DE 19803, USA. jgill@christianacare.org
authors.forename: James M
authors.initials: JM
authors.lastname: Gill
authors.forename: Mark K
authors.initials: MK
authors.lastname: Landis
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D002309:Cardiology / Q000592:standards*; D015331:Cohort Studies; D003691:Delaware; D006801:Humans; D019934:International Normalized Ratio / Q000451:nursing / Q000706:statistics & numerical data*; D008875:Middle Aged; D008952:Mobile Health Units / Q000458:organization & administration*; D009722:Nurse Practitioners / Q000193:education; D009819:Office Visits; D019982:Organizational Case Studies; D010353:Patient Education as Topic; D019095:Point-of-Care Systems; D015397:Program Evaluation; D015912:Thrombolytic Therapy / Q000451:nursing / Q000592:standards*; D017749:Total Quality Management / Q000379:methods* / Q000458:organization & administration; D014859:Warfarin / Q000008:administration & dosage* / Q000097:blood
chemical_list: D014859:Warfarin