title: The triad of weight loss, fever and night sweating: isolated bone marrow tuberculosis, a case report.
abstract: Extrapulmonary tuberculosis is known to be the infection in an organ with or without pulmonary involvement. The infection in extrapulmonary tuberculosis is insidious and the symptoms and signs are generally nonspecific. We describe a 56-year-old male patient complaining of weight loss, fever, and night sweats. Although there were no signs and symptoms attributable to pulmonary tuberculosis, polymerase chain reaction (PCR), microscobical and cultural examination of bone marrow aspirate revealed isolated bone marrow tuberculosis. A treatment protocol of isoniazid, rifampicin, pyrazinamide, and streptomycin was administered. After 9 months of treatment, re-examination of the bone marrow revealed no signs of tuberculosis. Tuberculosis should be kept in mind especially in endemic areas and bone marrow should be examined in case of suspected tuberculosis infection.
authors.affiliation: Inonu University, School of Medicine, Department of Internal Medicine, Antalya, Turkey. drsari@hotmail.com
authors.forename: R
authors.initials: R
authors.lastname: Sari
authors.forename: Y
authors.initials: Y
authors.lastname: Bayindir
authors.forename: A
authors.initials: A
authors.lastname: Sevinc
authors.forename: F
authors.initials: F
authors.lastname: Bahceci
authors.forename: S
authors.initials: S
authors.lastname: Ozen
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D001853:Bone Marrow / Q000473:pathology*; D003937:Diagnosis, Differential; D005334:Fever / Q000175:diagnosis*; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011718:Pyrazinamide / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D013307:Streptomycin / Q000627:therapeutic use; D013546:Sweating; D014391:Tuberculosis, Miliary / Q000175:diagnosis* / Q000188:drug therapy; D015431:Weight Loss
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin