title: Three-dimensional structure of a COPII prebudding complex.
abstract: The coat protein complex II (COPII) catalyzes transport vesicle formation from the endoplasmic reticulum. Crystallographic analysis of a Sec23/24-Sar1 prebudding complex of COPII now provides a molecular view of this GTPase-directed coat assembly mechanism.
authors.affiliation: Dartmouth Medical School, Department of Biochemistry, Hanover, NH 03755, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Barlowe
mesh_terms: D022181:COP-Coated Vesicles / Q000737:chemistry*; D020690:GTPase-Activating Proteins; D008565:Membrane Proteins / Q000737:chemistry; D020559:Monomeric GTP-Binding Proteins / Q000737:chemistry; D028861:Nuclear Pore Complex Proteins; D011485:Protein Binding; D011487:Protein Conformation; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry; D033921:Vesicular Transport Proteins
chemical_list: D020690:GTPase-Activating Proteins; D008565:Membrane Proteins; D028861:Nuclear Pore Complex Proteins; C079620:SEC13 protein, S cerevisiae; C079037:SEC23 protein, S cerevisiae; C118289:SEC24 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D033921:Vesicular Transport Proteins; D020559:Monomeric GTP-Binding Proteins; C077395:SAR1 protein, S cerevisiae