title: [Vanishing bile duct syndrome following allogeneic bone marrow transplantation].
abstract: BACKGROUND
  Cholestasis following bone marrow transplantation is not rare, but should always be a warning signal. The main causes of cholestasis following bone marrow transplantation are hepatotoxic effects of drugs, venoocclusive disease (VOD), early graft-versus-host disease (GvHD), total parenteral nutrition, viral hepatitis, sepsis and opportunistic infections. Vanishing bile duct syndrome represents a very rare cause for cholestatic symptoms.
  
  
  METHODS
  We report on a 8-year-old boy suffering from myelodysplastic syndrome, who underwent allogeneic bone marrow transplantation and developed biliary ductopenia in terms of a vanishing bile duct syndrome.
  
  
  CONCLUSIONS
  Differential diagnosis for cholestasis following bone marrow transplantation should include the vanishing bile duct syndrome.
authors.affiliation: Klinik für Kinder- und Jugendmedizin, Universitätskliniken des Saarlandes, Homburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Aliani
authors.forename: S
authors.initials: S
authors.lastname: Meyer
authors.forename: T
authors.initials: T
authors.lastname: Krenn
authors.forename: I
authors.initials: I
authors.lastname: Müller-Molaian
authors.forename: N
authors.initials: N
authors.lastname: Graf
mesh_terms: D001652:Bile Ducts / Q000473:pathology; D001706:Biopsy; D016026:Bone Marrow Transplantation; D002648:Child; D002779:Cholestasis / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D009190:Myelodysplastic Syndromes / Q000601:surgery; D011183:Postoperative Complications; D011379:Prognosis; D013577:Syndrome