Distal Cu ion protects synthetic heme/Cu analogues of cytochrome oxidase against inhibition by CO and cyanide.
Collman
James P
JP
Department of Chemistry, Stanford University, Stanford, CA 94305, USA. jps@stanford.edu
Boulatov
Roman
R
Shiryaeva
Irina M
IM
Sunderland
Christopher J
CJ
D000818:Animals; D001665:Binding Sites; D002248:Carbon Monoxide / Q000378:metabolism / Q000494:pharmacology*; D002384:Catalysis; D002417:Cattle; D003300:Copper / Q000737:chemistry* / Q000378:metabolism; D003486:Cyanides / Q000378:metabolism / Q000494:pharmacology*; D003576:Electron Transport Complex IV / Q000037:antagonists & inhibitors* / Q000737:chemistry* / Q000378:metabolism; D006418:Heme / Q000737:chemistry* / Q000378:metabolism; D007477:Ions / Q000737:chemistry / Q000378:metabolism; D007501:Iron / Q000378:metabolism; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000378:metabolism
D003486:Cyanides; D007477:Ions; D006418:Heme; D003300:Copper; D002248:Carbon Monoxide; D007501:Iron; D003576:Electron Transport Complex IV; D010100:Oxygen