title: Gardner's syndrome - a case report.
abstract: Gardner's syndrome is the association of multiple colonic polyps (familial adenomatous polyposis coli - FAP) with sebaceous cysts and jaw osteomas. The significance of this dominantly inherited condition to the dentist is that the colonic polyps usually undergo malignant change by the fourth decade and the extra-intestinal lesions may be apparent before those in the bowel. As such, early detection of multiple jaw osteomas and/or multiple sebaceous cysts (particularly on the scalp) may lead to appropriate further investigation and treatment which might be life saving. Diagnosis of this condition also has implications for other family members.
authors.affiliation: Dental Radiology and Assessment and Casualty, Charles Clifford Dental Hospital, Wellesley Road, Sheffield S10 2SZ. martin.payne@sth.nhs.uk
authors.forename: M
authors.initials: M
authors.lastname: Payne
authors.forename: J A
authors.initials: JA
authors.lastname: Anderson
authors.forename: J
authors.initials: J
authors.lastname: Cook
mesh_terms: D000328:Adult; D005260:Female; D005736:Gardner Syndrome / Q000150:complications / Q000175:diagnosis*; D017491:Genes, APC; D006801:Humans; D007417:Intestinal Polyps / Q000175:diagnosis / Q000601:surgery; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000209:etiology; D009154:Mutation; D010016:Osteoma / Q000175:diagnosis* / Q000209:etiology