Spatial frequency discrimination in schizophrenia.
Pathways within the visual system can be distinguished on the basis of selectivity for low or high spatial frequencies. Spatial frequency discrimination was evaluated in 17 medicated male patients with schizophrenia and 19 male control subjects. Subjects were required to discriminate whether pairs of high contrast, sinusoidally modulated gratings were the same or different in spatial frequency. Accuracy performance was compared at high, medium, and low spatial frequencies on tasks matched for control performance. Patients showed a greater performance decrement of 12% on low as compared with 4% on high spatial frequencies. These findings suggest a disturbance of right hemisphere mechanisms involved in spatial perception and attention in schizophrenia.
O'Donnell
Brian F
BF
Department of Psychology, Indiana University, Bloomington 47405, USA. bodonnel@indiana.edu
Potts
Geoffrey F
GF
Nestor
Paul G
PG
Stylianopoulos
Kiriaki C
KC
Shenton
Martha E
ME
McCarley
Robert W
RW
D000328:Adult; D000704:Analysis of Variance; D004192:Discrimination, Psychological / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013028:Space Perception / Q000502:physiology*