Effects of non-surgical treatment modalities on peri-implantitis.
OBJECTIVE
To evaluate the effects of local-delivery of 25% metronidazol gel and mechanical cleaning using ultrasonic carbon fiber tip on dental implants with peri-implantitis.


METHODS
27 implants with peri-implantitis were randomly assigned to receiving either 25% metronidazol gel treatment or carbon fiber tip ultrasonic scaling. All parameters including plaque index (PLI), probing depth (PD) of pocket, sulcular bleeding index (SBI), and BANA enzyme analysis were measured at baseline, 1, 2, 6 and 12 weeks after treatment.


RESULTS
Statistically significant decrease (P < 0.05) in SBI, BANA test and PLI occurred in both treatment groups at all time intervals compared to baseline. PD had a decreasing tendency in both groups, but only metronidazole group reached statistically significant level (P < 0.05) at 2 and 6 week intervals compared to baseline. None of the treatment modalities produced any side effects on the implant and peri-implant tissues.


CONCLUSIONS
Both 25% metronidazol gel and mechanical cleaning using ultrasonic carbon fiber tip can be safely and effectively used in the treatment of peri-implant diseases.
Tang
Zhihui
Z
Department of Periodontology, Peking University School of Stomatology, Beijing 100081, China.
Cao
Caifang
C
Sha
Yueqin
Y
Lin
Ye
Y
Wang
Xing
X
D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002244:Carbon; D015921:Dental Implants / Q000009:adverse effects* / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008875:Middle Aged; D010518:Periodontitis / Q000209:etiology / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D014465:Ultrasonics
D000890:Anti-Infective Agents; D015921:Dental Implants; D008795:Metronidazole; D002244:Carbon