Antibacterial cyclopeptide alkaloids from the bark of Condalia buxifolia.
The cyclopeptide alkaloid, named condaline-A, was isolated from the root bark of Condalia buxifolia Reissek (Rhamnaceae), along with the known compounds adouetine-Y', scutianine-B, and scutianine-C. Their structures were determined by spectroscopic analyses, with their antibacterial activities being evaluated by use of a direct bioautography method.
Morel
Ademir F
AF
Departamento de Química, Universidade Federal de Santa Maria, RS, Santa Maria, Brazil. afmorel@base.quimica.br
Araujo
Carla A
CA
da Silva
Ubiratan F
UF
Hoelzel
Solange C S M
SC
Záchia
Renato
R
Bastos
Nelci R
NR
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D024301:Plant Bark / Q000737:chemistry*; D027823:Rhamnaceae / Q000737:chemistry*
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D010456:Peptides, Cyclic; C473496:adouetine-Y'; C473495:condaline-A; C432973:scutianine C