title: Prevalence of thyroid antibodies in Thai patients with chronic idiopathic urticaria.
abstract: One hundred Thai patients with chronic idiopathic urticaria (CIU) were studied to determine the prevalence of thyroid antibodies in comparison to 100 age- and sex-matched healthy volunteers. It was found that 21 patients (21%) with CIU were positive for thyroid antibodies. Among normal volunteers, only nine cases (9%) had elevated titers of thyroid antibodies. The frequency of thyroid antibodies in the chronic urticaria group was significantly more common than the control group (chi-square = 4.75, p=0.03). Among 21 patients with CIU who were positive for thyroid antibodies, 9 cases were negative for thyroid antibodies when repeating the tests after 3 months. Only 12 patients still had persistent elevation of antibodies after 3 months and thyroid function test was performed in these 12 patients. It was found that 9 cases had autoimmune thyroiditis with euthyroidism. One case had subclinical hyperthyroidism. One case had autoimmune hyperthyroidism, One case had subclinical hypothyroidism.
authors.affiliation: Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Prisana
authors.initials: P
authors.lastname: Kullavanijaya
authors.forename: Gobchai
authors.initials: G
authors.lastname: Puavilai
authors.forename: Siripen
authors.initials: S
authors.lastname: Puavilai
authors.forename: Suwannee
authors.initials: S
authors.lastname: Chanprasertyothin
mesh_terms: D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D013785:Thailand / Q000453:epidemiology; D013959:Thyroid Diseases / Q000150:complications / Q000276:immunology*; D014581:Urticaria / Q000150:complications / Q000276:immunology*
chemical_list: D001323:Autoantibodies