title: Activity of disinfectants against Gram-negative bacilli isolated from patients undergoing lung transplantation for cystic fibrosis.
abstract: Lung transplant recipients with cystic fibrosis are frequently colonized with antibiotic-resistant bacteria. We evaluated the in vitro activity of 5 disinfectants frequently used in cardiac surgery against strains of Burkholderia cepacia and Pseudomonas aeruginosa isolated from patients undergoing sequential single lung transplantation. Our results suggest that the activity of Taurolin and Noxyflex is superior to conventional disinfectants.
authors.affiliation: Department of Microbiology, Freeman Hospital, Newcastle upon Tyne, UK.
authors.forename: John D
authors.initials: JD
authors.lastname: Perry
authors.forename: Gavin
authors.initials: G
authors.lastname: Riley
authors.forename: Susan
authors.initials: S
authors.lastname: Johnston
authors.forename: John H
authors.initials: JH
authors.lastname: Dark
authors.forename: F Kate
authors.initials: FK
authors.lastname: Gould
mesh_terms: D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D016956:Burkholderia cepacia / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology; D003550:Cystic Fibrosis / Q000601:surgery*; D004202:Disinfectants / Q000494:pharmacology*; D006801:Humans; D016040:Lung Transplantation; D009677:Noxythiolin / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013654:Taurine / Q000031:analogs & derivatives* / Q000494:pharmacology; D013829:Thiadiazines / Q000494:pharmacology; D014260:Triclosan / Q000494:pharmacology
chemical_list: D000891:Anti-Infective Agents, Local; D004202:Disinfectants; D013829:Thiadiazines; D013654:Taurine; D009677:Noxythiolin; D014260:Triclosan; C012566:taurolidine; D002710:Chlorhexidine