title: The discovery of novel neuropeptides takes flight.
abstract: Structural data are critical for the elucidation of how peptides are synthesized and how they function. Two recent studies have used nanoscale chromatography together with mass spectrometry to determine the structures of novel neuropeptides in rat and Drosophila. The results shed light on neuropeptide synthesis and function(s) in both vertebrates and insects.
authors.affiliation: Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109-0606, USA. nicholsr@umich.edu
authors.forename: Ruthann
authors.initials: R
authors.lastname: Nichols
mesh_terms: D000818:Animals; D002853:Chromatography, Liquid / Q000379:methods; D029721:Drosophila Proteins / Q000302:isolation & purification; D036103:Nanotechnology / Q000379:methods*; D009479:Neuropeptides / Q000302:isolation & purification*; D051381:Rats; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods
chemical_list: D029721:Drosophila Proteins; D009479:Neuropeptides