Synthesis of (+)-puraquinonic acid.
(+)-Puraquinonic acid (1a) was synthesized, using a route based on ring-closing metathesis and radical cyclization, the chirality of the quaternary carbon being controlled by a temporary adjacent asymmetric center.
Clive
Derrick L J
DL
Chemistry Department, University of Alberta, Edmonton, Alberta, Canada T6G 2G2.
Yu
Maolin
M
D000970:Antineoplastic Agents / Q000138:chemical synthesis; D003500:Cyclization; D005658:Fungi / Q000737:chemistry; D007192:Indenes / Q000138:chemical synthesis*; D013237:Stereoisomerism
D000970:Antineoplastic Agents; D007192:Indenes; C431681:puraquinonic acid