Axon guidance: Comm hither, Robo.
In the developing CNS, commissural axons are initially attracted to the midline, but after crossing they acquire sensitivity to midline repellent cues which prevent re-crossing. Recent studies have shed new light on the mechanism by which commissural axons change their sensitivity to guidance cues after crossing the midline.
Couch
Jessica
J
Department of Biology, 071 Gilmer Hall, University of Virginia, Charlottesville, VA 22903, USA.
Condron
Barry
B
D001369:Axons; D009419:Nerve Tissue Proteins; D011971:Receptors, Immunologic / Q000502:physiology*; D000097905:Roundabout Proteins
D009419:Nerve Tissue Proteins; D011971:Receptors, Immunologic; D000097905:Roundabout Proteins