title: The ProSeal laryngeal mask in myasthenia gravis.
abstract: This case describes the anaesthesia management of a patient with myasthenia gravis who required mastectomy with axillary lymph node clearance. After withholding medical therapy for the myasthenia preoperatively on the day of surgery, anaesthesia was maintained with halothane, nitrous oxide and a remifentanil infusion. Muscle relaxants were avoided, facilitated by the use of a ProSeal (Intravent, Orthofix, Maidenhead, United Kingdom) laryngeal mask airway for positive pressure ventilation. The ProSeal laryngeal mask airway is a new laryngeal mask device with a modified cuff and a drainage tube which has been shown to have advantages over older designs for use during positive pressure ventilation. The rationale for the management of this patient with myasthenia is discussed.
authors.affiliation: Department of Anaesthesia, University of Cape Town, Groote Schuur Hospital, Observatory, South Africa.
authors.forename: S V
authors.initials: SV
authors.lastname: Gardner
authors.forename: N R
authors.initials: NR
authors.lastname: Evans
mesh_terms: D000368:Aged; D000768:Anesthesia, General / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017214:Laryngeal Masks; D008408:Mastectomy / Q000379:methods; D009157:Myasthenia Gravis / Q000150:complications* / Q000175:diagnosis; D019990:Perioperative Care; D011175:Positive-Pressure Respiration; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous