A new paradigm for cationic cyclization of iron tricarbonyl diene complexes with pendant alkenes and arenes.
A new example of stereospecific cationic cyclization of iron tricarbonyl diene complexes with pendant alkenes and arenes is provided. Protonation of a double bond vicinal to the iron tricarbonyl diene moiety is employed to trigger the cyclization, rather than the previously reported Lewis/protic acid dehydroxylation of diastereomeric alcohols, eliminating one step of separation and avoiding some reactivity problems previously encountered for one of the alcohol diastereoisomers. [reaction: see text]
Pearson
Anthony J
AJ
Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA. ajp4@po.cwru.edu
Ghidu
Victor P
VP