title: Synthesis of a new water-soluble C(2)-symmetric chiral diamine: preliminary investigation of its catalytic properties for asymmetric hydrogenation under biphasic conditions.
abstract: A water-soluble version of N,N'-dimethyl-1,2-diphenylethane-1,2-diamine was prepared by introduction of phosphonic acid moieties on the para position of the aromatic rings. Preliminary investigation of the catalytic properties of the iridium complex of this ligand under biphasic conditions showed that this system compared well with the homogeneous counterpart for the asymmetric hydrogenation of ketones but with noticeably higher reaction rates for the biphasic system.
authors.affiliation: Laboratoire de Synthèse Organique, UMR CNRS 6513, 2 Rue de la Houssinière, BP92208, 44322 Nantes Cedex 03, France.
authors.forename: Céline
authors.initials: C
authors.lastname: Maillet
authors.forename: Thoniyot
authors.initials: T
authors.lastname: Praveen
authors.forename: Pascal
authors.initials: P
authors.lastname: Janvier
authors.forename: Sébastien
authors.initials: S
authors.lastname: Minguet
authors.forename: Michel
authors.initials: M
authors.lastname: Evain
authors.forename: Christine
authors.initials: C
authors.lastname: Saluzzo
authors.forename: M Lorraine
authors.initials: ML
authors.lastname: Tommasino
authors.forename: Bruno
authors.initials: B
authors.lastname: Bujoli