Cytogenetics and molecular genetics of bladder cancer: a personal view.
The cytogenetic and molecular genetic aspects that may be involved in the pathogenesis of bladder cancer are presented. Although anomalies of chromosome 9 may play an initial causative role in this cancer, the subsequent events, involving a succession of genetic changes, are less established or understood. This presentation is a distillation of what generally are considered to be the cytogenetic and molecular genetic events that constitute the array of changes underlying bladder cancer.
Sandberg
Avery A
AA
Department of DNA Diagnostics at St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA. jvaugha@chw.edu
D002869:Chromosome Aberrations; D002899:Chromosomes, Human, Pair 9; D006801:Humans; D001749:Urinary Bladder Neoplasms / Q000209:etiology / Q000235:genetics*