title: [Two years experience with the new accommodative 1 CU intraocular lens].
abstract: After marked improvement of optical rehabilitation of cataract patients during the last decades due to small incision surgery and foldable intraocular lenses (IOL), presbyopia is now one of the great unsolved questions in ophthalmology. During recent years a new accommodative IOL, the 1CU lens, has been developed based on the concepts of K.D. Hanna and on finite element computer simulation models. The 1CU IOL is designed to transform contracting forces of the ciliary muscle into anterior movement of the IOL optic (optic-shift concept). After the first implantation of a 1CU IOL in Erlangen in June 2000, we have now successfully implanted the 1CU IOL in over 90 patients. Our experiences and the results of several clinical studies indicate good and safe implantability, good centration, no IOL-specific complications, and good distance visual acuity. In comparison to control groups with conventional IOL, patients with the 1CU enjoyed significantly better distance-corrected near visual acuity, a larger accommodative range, and increased anterior and posterior axial movement of the lens optic after medical stimulation or inhibition of the ciliary muscle. We interpret our results as confirmation of the optic-shift concept of the 1CU IOL. Overall, the concept of accommodative IOL appears attractive and may have a great potential in the future. Additional studies including randomized blind multicenter evaluation of the 1CU IOL are necessary to further evaluate long-term and accommodative results.
authors.affiliation: Augenklinik mit Poliklinik der Universität Erlangen-Nürnberg, Erlangen, Germany. kuechle@augen.imed.uni-erlangen.de
authors.forename: M
authors.initials: M
authors.lastname: Küchle
authors.forename: N X
authors.initials: NX
authors.lastname: Nguyen
authors.forename: A
authors.initials: A
authors.lastname: Langenbucher
authors.forename: G C
authors.initials: GC
authors.lastname: Gusek-Schneider
authors.forename: B
authors.initials: B
authors.lastname: Seitz
mesh_terms: D000065:Accommodation, Ocular; D000368:Aged; D002386:Cataract; D002387:Cataract Extraction; D016001:Confidence Intervals; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D018918:Phacoemulsification; D010865:Pilot Projects; D011305:Presbyopia; D011474:Prosthesis Design; D013997:Time Factors; D014792:Visual Acuity