[Study of the real situation of improvement by Zopiclone in treatment of insomnia among persons working during night shifts].
We investigated the effect of adapted management of sleep on the duration and quality of sleep in shift workers working the night shift. Twenty-nine shift workers suffering from insomnia were included and treated with zopiclone (7.5mg/day) or placebo according to a random double-blind protocol. Patients completed a sleep diary and a wrist actigraph was used to evaluate episodes of rest/activity. A self-administered subjective sleep questionnaire was filled out just after awakening. Zopicone was found to increase the duration of sleep significantly (p<0.05) over the baseline duration after the first and second night on duty. Subjective estimation of sleep was better in patients taking zopiclone who exhibited a smaller number of shorter awakening episodes.


CONCLUSIONS
zopiclone improves the quality and duration of sleep in shift workers suffering from insomnia.
Quera-Salva
M A
MA
Hôpital Raymond Poincaré, AP-HP, Université Paris Ouest, Garches.
Philip
P
P
Taillard
J
J
Letrequeser
R
R
Allain
H
H
Garcia-Acosta
S
S
Kermad
I
I
Krieger
J
J
Dib
M
M
D000328:Adult; D053961:Azabicyclo Compounds; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000188:drug therapy*; D010879:Piperazines / Q000627:therapeutic use*; D020178:Sleep Disorders, Circadian Rhythm / Q000188:drug therapy*; D014851:Wakefulness
D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone