A new peroxinectin-like gene preferentially expressed during oogenesis and early embryogenesis in Drosophila melanogaster.
Several peroxidase isozymes have been described in Drosophila melanogaster. We describe a peroxinectin-like gene (Dpxt) in D. melanogaster. Peroxinectin is a cell-adhesive hemoperoxidase which binds superoxide dismutase and mediates blood cells attachment and spreading in the crayfish Pacifastacus leniusculus. The Dpxt predicted protein has a putative RGD-integrin binding tripeptide. The Dpxt mRNA is present in high amounts in late oogenesis and in early embryogenesis until the cellular blastoderm stage. It is virtually absent at other stages of the Drosophila life cycle, suggesting that Dpxt function is restricted to the early stages of fly development.
Vázquez
Martha
M
Dpto de Fisiología Molecular y Genética del Desarrollo, Inst de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca. mvazquez@ibt.unam.mx
Rodríguez
Rocío
R
Zurita
Mario
M
D000595:Amino Acid Sequence; D000818:Animals; D001798:Blood Proteins / Q000235:genetics*; D015815:Cell Adhesion Molecules / Q000235:genetics*; D029721:Drosophila Proteins / Q000235:genetics*; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000502:physiology*; D008969:Molecular Sequence Data; D009866:Oogenesis / Q000502:physiology*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D001798:Blood Proteins; D015815:Cell Adhesion Molecules; D029721:Drosophila Proteins; C096867:peroxinectin protein, Pacifastacus leniusculus