title: Osteosarcoma around the knee. Intraepiphyseal excision and biological reconstruction with distraction osteogenesis.
abstract: In 11 patients juxta-articular osteosarcoma around the knee was treated by intraepiphyseal excision of the tumour and reconstruction of the bone defect by distraction osteogenesis. Preoperative and postoperative chemotherapy was given to eight patients with high-grade tumours. The articular cartilage of the epiphysis and a maximum of healthy soft tissues were preserved. Distraction osteogenesis was then carried out. The mean gain in length was 9.7 cm. Full function of the limb was preserved in all except one patient, with a mean follow-up of 53.8 months. Treatment of juxta-articular osteosarcomas around the knee with joint preservation and biological reconstruction using distraction osteogenesis can give excellent functional results.
authors.affiliation: Department of Orthopaedic Surgery, School of Medicine, Kanazawa University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tsuchiya
authors.forename: M E
authors.initials: ME
authors.lastname: Abdel-Wanis
authors.forename: K
authors.initials: K
authors.lastname: Sakurakichi
authors.forename: T
authors.initials: T
authors.lastname: Yamashiro
authors.forename: K
authors.initials: K
authors.lastname: Tomita
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery*; D002648:Child; D003131:Combined Modality Therapy; D004838:Epiphyses / Q000601:surgery; D005260:Female; D005266:Femoral Neoplasms / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007719:Knee Joint; D008297:Male; D019857:Osteogenesis, Distraction; D012516:Osteosarcoma / Q000188:drug therapy / Q000601:surgery*; D013977:Tibia; D016896:Treatment Outcome