Synthesis and biological activity of isoamoenylin, a metabolite of Dendrobium amoenum.
Isoamoenylin (6), a dihydrostilbene from Dendrobium amoenum, was synthesised from 3,4,5-trimethoxybenzaldehyde (1) in four steps with an overall yield of 60%. The spectral data for synthetic 6 are in good agreement with those of the natural product. Isoamoenylin showed moderate antioxidative and weak antibacterial activities.
Venkateswarlu
Somepalli
S
Laila Impex R & D Centre, Unit I, Phase III, Jawahar Autonagar, Vijayawada 520 007, India.
Raju
Mudunuri S S
MS
Subbaraju
Gottumukkala V
GV
D000935:Antifungal Agents / Q000096:biosynthesis* / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects; D001234:Aspergillus niger / Q000187:drug effects; D031667:Dendrobium / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000378:metabolism; D007202:Indicators and Reagents; D008826:Microbial Sensitivity Tests; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013267:Stilbenes / Q000378:metabolism* / Q000494:pharmacology*; D013481:Superoxides / Q000378:metabolism
D000935:Antifungal Agents; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D012997:Solvents; D013267:Stilbenes; D013481:Superoxides; C473620:isoamoenylin