title: An avian model of limb deviation induced by periosteal surgery.
abstract: A model of limb deviation induced by hemi-circumferential periosteal stripping of the distal tibiotarsus of domestic chicks is described. This model has been developed to study the effects of periosteal stripping on the cellular, mechanical, vascular, and biochemical status of the immature bone and growth plate. It is hoped that such studies may further elucidate the mechanisms involved in altered bone growth following periosteal stripping techniques which are used in human and equine orthopaedics for the management of leg length discrepancies and angular limb deformities respectively (Auer and Martens 1980, Warrell and Baker 1987). Hemi-circumferential periosteal stripping of the left distal tibiotarsus of 28-day-old chicks resulted in significant change in metaphyseal-diaphyseal angle with time, compared to both the controls and the untreated right legs (P<0.0001). This model of limb deviation developed rapidly and consistently, and the procedures were well tolerated by the birds over the short survival time (maximum 28 days).
authors.affiliation: Department of Veterinary Surgery, Faculty of Veterinary Medicine, University College Dublin, Belfield, Ireland. sue.rackard@ucd.ie
authors.forename: S M
authors.initials: SM
authors.lastname: Rackard
authors.forename: A J
authors.initials: AJ
authors.lastname: Carr
authors.forename: J J
authors.initials: JJ
authors.lastname: Callanan
authors.forename: C R
authors.initials: CR
authors.lastname: Bellenger
mesh_terms: D000818:Animals; D001848:Bone Diseases, Developmental / Q000209:etiology* / Q000662:veterinary*; D002350:Carpus, Animal / Q000601:surgery*; D002645:Chickens / Q000601:surgery*; D004195:Disease Models, Animal; D008297:Male; D010521:Periosteum / Q000601:surgery*