title: [Renoprotective effect of monopril in patients with diabetes mellitus in the preclinical stage of diabetic nephropathy].
abstract: As many as 15 patients with insulin-dependent diabetes mellitus received monopril in a dose of 5 mg daily. Studied in the patients was the drug effect on the functional renal reserve and glomerular filtration rate. Determination of the functional renal reserve has been shown to be a criterion for an early diagnosis of the preclinical stage of diabetic nephropathy. Administration of monopril in exhausted functional renal reserve permits preventing development of proteinuria or allows a lapse of time for it to develop.
authors.forename: I I
authors.initials: II
authors.lastname: Lapchyns'ka
authors.forename: T Ie
authors.initials: TIe
authors.lastname: Zhurylo
authors.forename: M M
authors.initials: MM
authors.lastname: Seliuk
authors.forename: A Ie
authors.initials: AIe
authors.lastname: Hromova
mesh_terms: D000328:Adult; D000419:Albuminuria / Q000188:drug therapy / Q000209:etiology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D003928:Diabetic Nephropathies / Q000150:complications / Q000503:physiopathology / Q000517:prevention & control*; D005260:Female; D017328:Fosinopril / Q000627:therapeutic use*; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D017328:Fosinopril