title: Postoperative olfaction in chronic sinusitis: smokers versus nonsmokers.
abstract: In order to study the efficacy of surgical intervention, as well as the influence of cigarette smoking on olfaction in clinical states, we examined olfactory ability by means of the University of Pennsylvania Smell Identification Test (UPSIT). We enrolled 37 patients 21 to 60 years of age who underwent surgery for chronic sinusitis. Normosmia was defined as an UPSIT score of 30 or more. Among these patients, 31 had a disturbance in their smelling ability in the preoperative stage, and the improvement rate, defined as a rise in score of 4 or more points after surgery, was 64.5%; 11 were well healed. However, all 7 patients who were more than 40 years old at the time of surgery, and currently smoking cigarettes, had a significant deficit in olfaction in the preoperative stage and even in the postoperative stage. This study demonstrated that cigarette smoking has adverse effects on olfactory ability, especially for older patients.
authors.affiliation: Department of Otorhinolaryngology, Meijo Hospital, Nagoya, Japan.
authors.forename: Kazuko
authors.initials: K
authors.lastname: Sugiyama
authors.forename: Toshi
authors.initials: T
authors.lastname: Matsuda
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kondo
authors.forename: Shoji
authors.initials: S
authors.lastname: Mitsuya
authors.forename: Motoyuki
authors.initials: M
authors.lastname: Hashiba
authors.forename: Shingo
authors.initials: S
authors.lastname: Murakami
authors.forename: Shunkichi
authors.initials: S
authors.lastname: Baba
mesh_terms: D000328:Adult; D000367:Age Factors; D002908:Chronic Disease; D003627:Data Interpretation, Statistical; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000857:Olfaction Disorders / Q000175:diagnosis / Q000209:etiology*; D011184:Postoperative Period; D011379:Prognosis; D012852:Sinusitis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D012903:Smell; D012907:Smoking / Q000009:adverse effects*; D013997:Time Factors; D014057:Tomography, X-Ray Computed