Clerodane diterpenes from Baccharis sagittalis: insect antifeedant activity.
Two clerodane-type diterpene glycosides esters, which were studied as peracetyl derivatives, together with the known diterpene marrubiagenine, were isolated from the aerial part of Baccharis sagittalis (Less). Their structures were established by spectroscopic methods. Antifeedant activity toward Tenebrio molitor larvae of the isolated compounds along with six other diterpenes was evaluated and some structure-antifeedant bioactivity relationships are reported.
Cifuente
Diego A
DA
INTEQUI-CONICET-Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Chacabuco y Pedernera-5700-San Luis, Argentina.
Borkowski
Eduardo J
EJ
Sosa
Marta E
ME
Gianello
José C
JC
Giordano
Oscar S
OS
Tonn
Carlos E
CE
D000818:Animals; D031175:Baccharis / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology*; D045785:Diterpenes, Clerodane; D005247:Feeding Behavior / Q000187:drug effects; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D013712:Tenebrio / Q000187:drug effects
D004224:Diterpenes; D045785:Diterpenes, Clerodane; D007306:Insecticides