title: Effect of maternal oral hydration on amniotic fluid index in women with pregnancy-induced hypertension.
abstract: OBJECTIVE
  To evaluate the effect of maternal oral hydration on amniotic fluid index (AFI) in women with pregnancy-induced hypertension.
  
  
  METHODS
  Five women with pregnancy-induced hypertension and five normotensive gravidae at 32-37 weeks gestation with normal AFI (8-18cm) were hydrated by oral intake of 2L of water over 1 h. Both groups were similar in age, parity and gestation. Repeat AFI was measured in all women after 3 h. The differences between pre- and post-hydration AFI in the two groups were analyzed with Student's t-test for statistical significance.
  
  
  RESULTS
  Maternal oral hydration resulted in a significant increase in AFI in both hypertensive and normotensive gravidae (1.7cm and 3.48cm, respectively). However, the extent of increase was significantly lower in the hypertensive group (P = 0.03).
  
  
  CONCLUSIONS
  Pregnancy-induced hypertension adversely affects the increase in amniotic fluid volume with maternal hydration. This observation is of clinical relevance in the management of oligohydramnios associated with pregnancy-induced hypertension.
authors.affiliation: Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi. bhawnams@hotmail.com
authors.forename: Bhawna
authors.initials: B
authors.lastname: Malhotra
authors.forename: Deepika
authors.initials: D
authors.lastname: Deka
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000653:Amniotic Fluid / Q000502:physiology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000517:prevention & control*; D016104:Oligohydramnios / Q000517:prevention & control*; D010865:Pilot Projects; D011247:Pregnancy / Q000502:physiology*; D011249:Pregnancy Complications, Cardiovascular / Q000517:prevention & control*; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D015532:Rehydration Solutions / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D015532:Rehydration Solutions