What is paradoxical about Levinthal paradox?
We would be tempted to state that there has never been a Levinthal paradox. Indeed, Levinthal raised an interesting problem about protein folding, as he realized that proteins have no time to explore exhaustively their conformational space on the way to their native structure. He did not seem to find this paradoxical and immediately proposed a straightforward solution, which has essentially never been refuted. In other words, Levinthal solved his own paradox.
Rooman
Marianne
M
Ingénierie Biomoléculaire, Université Libre de Bruxelles, CP 165/64, 50 Avenue Roosevelt, Belgium. mrooman@ulb.ac.be
Dehouck
Yves
Y
Kwasigroch
Jean Marc
JM
Biot
Christophe
C
Gilis
Dimitri
D
D000595:Amino Acid Sequence; D019143:Evolution, Molecular; D007700:Kinetics; D008956:Models, Chemical; D011489:Protein Denaturation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism
D011506:Proteins