title: Axial flow catheter pump for circulatory support.
abstract: OBJECTIVE
  The development of a percutaneously insertable catheter pump for temporary left ventricular and circulatory support in patients with acute ischemic cardiomyopathy.
  
  
  METHODS
  The expandable axial flow pump (introduction diameter 9-F, expanded diameter 6.5 mm) is mounted at the tip of a catheter, designed to be placed in aortic transvalvular position. Hydrodynamic tests were performed in a static flow model and in a pulsatile mock circuit (Medos VAD, Stolberg, Germany). Cardiogenic shock was simulating in vitro and in vivo.
  
  
  RESULTS
  At a rotation speed of 32,000 rpm the catheter pump delivered a maximum flow of more than 4.0 L/min against a systemic mean pressure of 60 mmHg. Under shock simulation the pump significantly improved output and systemic pressure.
  
  
  CONCLUSIONS
  A percutaneously insertable catheter pump is technically feasible. Hydrodynamic efficacy allows sufficient cardiac support under simulated shock condition.
authors.affiliation: Clinic for Diagnostic Radiology, University of Technology Aachen, Germany. smiro@rad.rwth-aachen.de
authors.forename: T
authors.initials: T
authors.lastname: Schmitz-Rode
authors.forename: J G
authors.initials: JG
authors.lastname: Pfeffer
authors.forename: S
authors.initials: S
authors.lastname: Graf
authors.forename: F
authors.initials: F
authors.lastname: Buss
authors.forename: C
authors.initials: C
authors.lastname: Brücker
authors.forename: T
authors.initials: T
authors.lastname: Siess
authors.forename: R W
authors.initials: RW
authors.lastname: Günther
mesh_terms: D000818:Animals; D006328:Cardiac Catheterization / Q000295:instrumentation*; D002302:Cardiac Output / Q000502:physiology; D004867:Equipment Design; D006353:Heart-Assist Devices; D006461:Hemolysis / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000628:therapy*; D012770:Shock, Cardiogenic / Q000503:physiopathology / Q000628:therapy*