title: [Nutrition and body weight].
abstract: Certain dietary components play a key role for the development of coronary artery disease (CAD). Complex carbohydrates lower the prevalence of CAD. Protein should provide 15% of daily calories. Populations with a high consumption of soy protein have a low coronary event rate and a high life expectancy. Soy protein has a favorable effect on LDL cholesterol, triglycerides and HDL cholesterol. Dietary cholesterol correlates with an increased incidence of CAD. Saturated fats increase cholesterol levels as well as the activity of clotting factor VII and promote progression of CAD. Mono-(MUFA) and poly-unsaturated fatty acids lower LDL-cholesterol to a similar extent. MUFA are contained in rape seed oil, olive oil and pea nut oil, but also in avocados and almonds. Omega-3-fatty acids are in fatty fish like salmon, tuna and herring and improve survival after myocardial infarction. They improve among others endothelial function (adhesion molecules). Eating 1-2 fish meals per week has a preventive effect on CAD and stroke. Dietary fiber decreases the risk for CAD up to 30% and favorably influences carbohydrate metabolism. Antioxidants have a favorable effect in their natural form (fruits and fresh vegetables). The secondary preventive effect of a mediterranean diet after myocardial infarction (probably by a combination of the above effects) has been validated. Body weight correlates with coronary risk, diabetes and use of health care resources. A reduction of body weight is best achieved by calory reduction plus an increase of physical activity. A calory-adjusted diet, low in total fat with a significant proportion of unsaturated fats and omega-3-fatty acids and rich in fiber is of great importance for primary and secondary prevention of cardiovascular diseases. Fruits, vegetables and whole grain products are important components of this diet, which lowers the coronary event rate, increases longevity and is associated with a low rate of malignancies and osteoporosis.
authors.affiliation: Klinische Kardiologie II Herz-Zentrum Bad Krozingen Südring 15 79189 Bad Krozingen, Germany. helmut.gohlke@herzzentrum.de
authors.forename: H
authors.initials: H
authors.lastname: Gohlke
mesh_terms: D001835:Body Weight; D002791:Cholesterol, Dietary / Q000009:adverse effects; D003324:Coronary Artery Disease / Q000209:etiology / Q000517:prevention & control*; D002149:Energy Intake; D005247:Feeding Behavior; D006801:Humans; D009203:Myocardial Infarction / Q000209:etiology / Q000517:prevention & control; D012008:Recurrence; D012307:Risk Factors
chemical_list: D002791:Cholesterol, Dietary