title: Desflurane: a reappraisal.
abstract: Desflurane use is associated with carbon monoxide production and sympathetic activation. These side effects can be eliminated taking into account certain recommendations such as closing fresh gas flow at the end of anaesthesia, regular replacement of carbon dioxide absorbents and the use of new absorbents for carbon monoxide production and opioid administration with slow increases of inspiration concentrations during desflurane initiation for sympathetic activation.
authors.affiliation: Department of Anesthesiology, Academisch Ziekenhuis Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090 Brussel, Belgium.
authors.forename: V
authors.initials: V
authors.lastname: Umbrain
authors.forename: L
authors.initials: L
authors.lastname: Shi
authors.forename: Fr
authors.initials: F
authors.lastname: Camu
mesh_terms: D000764:Anesthesia, Closed-Circuit / Q000009:adverse effects; D018685:Anesthetics, Inhalation / Q000009:adverse effects* / Q000737:chemistry; D000818:Animals; D002248:Carbon Monoxide / Q000737:chemistry; D002249:Carbon Monoxide Poisoning / Q000209:etiology; D003327:Coronary Disease / Q000503:physiopathology; D000077335:Desflurane; D006801:Humans; D007530:Isoflurane / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000737:chemistry; D008305:Malignant Hyperthermia / Q000209:etiology; D012137:Respiratory System / Q000187:drug effects; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000503:physiopathology
chemical_list: D018685:Anesthetics, Inhalation; D002248:Carbon Monoxide; D000077335:Desflurane; D007530:Isoflurane