Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 ( PSPLA1).
We report the identification of nine DNA polymorphisms in PSPLA1 encoding phosphatidylserine-specific phospholipase A1. Because the gene product shares homology with triglyceride lipases, these polymorphisms may be useful in association studies with metabolic traits such as hypertriglyceridemia and related lipoprotein abnormalities, and will also provide tools for mapping studies of chromosome 3q13.13-13.2.
Wang
Jian
J
Blackburn Cardiovascular Genetics Laboratory, Robarts Research Institute, 406-100 Perth Drive, London, ON N6A 5K8, Canada.
Wen
Xiao-Yan
XY
Stewart
A Keith
AK
Hegele
Robert A
RA
D005260:Female; D005787:Gene Frequency; D006801:Humans; D015228:Hypertriglyceridemia / Q000235:genetics; D008297:Male; D008969:Molecular Sequence Data; D010741:Phospholipases A / Q000235:genetics*; D054466:Phospholipases A1; D011110:Polymorphism, Genetic; D014280:Triglycerides / Q000097:blood; D044465:White People / Q000235:genetics
D014280:Triglycerides; C512665:PLA1A protein, human; D010741:Phospholipases A; D054466:Phospholipases A1