title: Familial clustering of obesity and the role of nutrition: Tehran Lipid and Glucose Study.
abstract: OBJECTIVE
  To clarify the hypothesis that parent's dietary intakes are associated with their offspring's body mass index.
  
  
  METHODS
  Observational analytical cross-sectional survey among inhabitants of district 13 in the east of Tehran.
  
  
  METHODS
  A total of 117 healthy families comprising 474 subjects including 240 offspring (3-25 y old).
  
  
  METHODS
  Weight and height were measured by a standard protocol and body mass index (kg/m(2)) was calculated. Dietary intakes were assessed by means of a 2 day dietary recall questionnaire.
  
  
  RESULTS
  The prevalence of overweight was 11.8% in offspring of normal-weight parents, 19.0% in offspring of overweight fathers and normal-weight mothers, 25.4% in offspring of overweight mothers and normal-weight fathers and 40.8% in offspring with both parents overweight. The Offspring's overweight was significantly and independently associated with high-energy intake of both parents (odds ratio; 95% CI 2.7; 1.6-4.5). Adjusted for the sex of parents, the chances of offspring being overweight were higher in overweight (3.8; 1.5-9.2) and high-energy-intake mothers (2.6; 1.2-5.6) and high-energy-intake fathers (2.0; 1.1-3.9) as compared with children of normal-weight parents. High fat intake of husbands was an independent risk factor increasing the chances of their wives being overweight (2.1; 1.5-3.6) and vice versa (1.8; 1.2-2.8).
  
  
  CONCLUSIONS
  The observed familial obesity pattern was shown to be associated with the familial dietary intakes. Hence, familial intervention seems essential to stop the accelerated rise in the prevalence of overweight and obesity in our community.
authors.affiliation: Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: P
authors.initials: P
authors.lastname: Mirmiran
authors.forename: M
authors.initials: M
authors.lastname: Mirbolooki
authors.forename: F
authors.initials: F
authors.lastname: Azizi
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D002149:Energy Intake; D005247:Feeding Behavior / Q000523:psychology*; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D009765:Obesity / Q000453:epidemiology / Q000235:genetics* / Q000523:psychology; D016017:Odds Ratio; D010287:Parent-Child Relations; D010375:Pedigree