title: COX-2-selective inhibitors: clinical relevance in surgical and acute pain.
authors.affiliation: University of Leicester, University Department of Anaesthesia, Leicester Royal Infirmary, Leicester, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Rowbotham
mesh_terms: D000208:Acute Disease; D000700:Analgesics / Q000627:therapeutic use; D000818:Animals; D000068579:Celecoxib; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D007555:Isoxazoles / Q000009:adverse effects / Q000627:therapeutic use; D008565:Membrane Proteins; D010146:Pain / Q000188:drug therapy*; D010149:Postoperative Pain / Q000188:drug therapy; D011451:Prostaglandin-Endoperoxide Synthases; D011720:Pyrazoles; D013449:Sulfonamides / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D007555:Isoxazoles; D008565:Membrane Proteins; D011720:Pyrazoles; D013449:Sulfonamides; C409945:parecoxib; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases; D000068579:Celecoxib