Pine resin and biopin ointment: effects of water-soluble fractions on functional activity of peripheral blood neutrophils.
We studied the effects of water-soluble fractions of pine resin and Biopin-10 and Biopin-20 ointments used in the treatment of burns, wounds, and pyoinflammatory processes on the phagocytic activity and redox potential of human peripheral blood neutrophils in vitro. The test preparations contain bioactive substances producing opposite dose-dependent effects on phagocytosis, which suggests that the composition and dose of ointments should be selected individually in order to attain the optimal therapeutic effect.
Simbirtsev
A S
AS
Konusova
V G
VG
McHedlidze
G Sh
GSh
Paramonov
B A
BA
Chebotarev
V Yu
VY
D004305:Dose-Response Relationship, Drug; D006801:Humans; D009504:Neutrophils / Q000187:drug effects* / Q000502:physiology; D009824:Ointments / Q000494:pharmacology; D010084:Oxidation-Reduction / Q000187:drug effects; D010587:Phagocytosis / Q000187:drug effects; D012116:Resins, Plant / Q000494:pharmacology*; D013997:Time Factors
D009824:Ointments; D012116:Resins, Plant; C013893:rosin