title: The design and synthesis of artificial photosynthetic antennas, reaction centres and membranes.
abstract: Artificial antenna systems and reaction centres synthesized in our laboratory are used to illustrate that structural and thermodynamic factors controlling energy and electron transfer in these constructs can be modified to optimize performance. Artificial reaction centres have been incorporated into liposomal membranes where they convert light energy to vectorial redox potential. This redox potential drives a Mitchellian, quinone-based, proton-transporting redox loop that generates a Deltamu H(+) of ca. 4.4 kcal mol(-1) comprising DeltapH ca. 2.1 and Deltapsi ca. 70 mV. In liposomes containing CF(0)F(1)-ATP synthase, this system drives ATP synthesis against an ATP chemical potential similar to that observed in natural systems.
authors.affiliation: Department of Chemistry and Biochemistry and Centre for the Study of Early Events in Photosynthesis, Arizona State University, Tempe, AZ 85287-1604, USA. tmoore@asu.edu
authors.forename: T A
authors.initials: TA
authors.lastname: Moore
authors.forename: A L
authors.initials: AL
authors.lastname: Moore
authors.forename: D
authors.initials: D
authors.lastname: Gust
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D002338:Carotenoids / Q000737:chemistry / Q000378:metabolism; D004579:Electron Transport; D004735:Energy Transfer; D037741:Fullerenes / Q000737:chemistry; D008027:Light; D008567:Membranes, Artificial; D015394:Molecular Structure; D010777:Photochemistry; D010788:Photosynthesis; D045322:Photosynthetic Reaction Center Complex Proteins / Q000138:chemical synthesis* / Q000378:metabolism*; D010944:Plants / Q000378:metabolism; D011166:Porphyrins / Q000737:chemistry; D017494:Proton Pumps / Q000378:metabolism; D013997:Time Factors
chemical_list: D037741:Fullerenes; D008567:Membranes, Artificial; D045322:Photosynthetic Reaction Center Complex Proteins; D011166:Porphyrins; D017494:Proton Pumps; D002338:Carotenoids; D000255:Adenosine Triphosphate