title: [Nitric oxide as an adaptive protection factor in hypoxia].
abstract: Recent data concerning intracellular aspects of nitric oxide at hypoxia conditions and correction means pathologic states by it. On the basis of data obtained publications and own investigations about nitric oxide influence on mitochondrial respiration and oxidative phosphorylation possible mechanism its action is discussed. We conclude that breach of macroergs output at hypoxia connect with active oxygen forms, antioxidant enzymes activity and individual peculiarities physiologic reactivity of organism.
authors.affiliation: Ivan Franko Lviv National University, Lviv, Ukraine.
authors.forename: N N
authors.initials: NN
authors.lastname: Kurgaliuk
mesh_terms: D000222:Adaptation, Physiological; D003576:Electron Transport Complex IV / Q000037:antagonists & inhibitors; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D000860:Hypoxia / Q000503:physiopathology*; D008928:Mitochondria / Q000201:enzymology / Q000378:metabolism; D009569:Nitric Oxide / Q000096:biosynthesis* / Q000502:physiology; D020030:Nitric Oxide Donors / Q000494:pharmacology; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D010085:Oxidative Phosphorylation; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology
chemical_list: D004791:Enzyme Inhibitors; D020030:Nitric Oxide Donors; D017382:Reactive Oxygen Species; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D003576:Electron Transport Complex IV