[The efficacy of radio-iodine-therapy in patients with differentiated form cancer of thyroid gland in various after thyroidectomy].
Results of treatment of 376 patients, ageing 18-76 yrs, were analyzed to investigate the radioiodine therapy (RITH) efficacy for the thyroid differentiated cancer depending on the term of its conduction after the operation. In patients with the thyroid gland residual tissue (THGRT) only the first course of RITH efficacy was 82.6-96.1%, the THGRT and metastases devitalization in regional lymph nodes and lungs was achieved in 72.7-81.6% of patients. The RITH courses number had constituted 2.5-6.3 at average and median summary activity for one patient--11-33.8 GBq. It was suggested that tendency for the courses number and summary activity enhancement in patients with regional and distant metastases was caused by the tumor tissue mass increase according to elongation the period of time between thyroidectomy and RITH conduction. It is necessary to determine the RITH conduction urgency, basing on the risk factors analysis.
Shishkina
V V
VV
Chebotareva
E D
ED
Dzhuzha
D A
DA
Siniuta
B F
BF
D000293:Adolescent; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D012711:Serum Albumin, Radio-Iodinated / Q000627:therapeutic use*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*
D019275:Radiopharmaceuticals; D012711:Serum Albumin, Radio-Iodinated