title: A new intraocular lens design to reduce spherical aberration of pseudophakic eyes.
abstract: OBJECTIVE
  The aim of this study was to design and evaluate in the laboratory a new intraocular lens (IOL) intended to provide superior ocular optical quality by reducing spherical aberration.
  
  
  METHODS
  Corneal topography measurements were performed on 71 cataract patients using an Orbscan I. The measured corneal surface shapes were used to determine the wavefront aberration of each cornea. A model cornea was then designed to reproduce the measured average spherical aberration. This model cornea was used to design IOLs having a fixed amount of negative spherical aberration that partially compensates for the average positive spherical aberration of the cornea. Theoretical and physical eye models were used to assess the expected improvement in optical quality of an eye implanted with this lens.
  
  
  RESULTS
  Measurements of optical quality provided evidence that if this modified prolate IOL was centered within 0.4 mm and tilted less than 7 degrees, it would exceed the optical performance of a conventional spherical IOL. This improvement occurred without an apparent loss in depth of focus.
  
  
  CONCLUSIONS
  A new IOL with a prolate anterior surface, designed to partially compensate for the average spherical aberration of the cornea, is intended to improve the ocular optical quality of pseudophakic patients.
authors.affiliation: Baylor College of Medicine, Holladay LASIK Institute, Houston, TX, USA.
authors.forename: Jack T
authors.initials: JT
authors.lastname: Holladay
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Piers
authors.forename: Gabor
authors.initials: G
authors.lastname: Koranyi
authors.forename: Marrie
authors.initials: M
authors.lastname: van der Mooren
authors.forename: N E Sverker
authors.initials: NE
authors.lastname: Norrby
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D019781:Corneal Topography; D004867:Equipment Design; D005260:Female; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D008953:Models, Anatomic; D055095:Optics and Photonics; D014786:Vision Disorders / Q000517:prevention & control*; D014785:Vision, Ocular