title: Bilobed splitting of median nerve somatosensory evoked p14 potential under deep hypothermia.
abstract: OBJECTIVE
  To further elucidate temperature related changes in subcortical components of somatosensory evoked potentials (SEP) in intraoperative monitoring.
  
  
  METHODS
  Intraoperative monitoring of subcortical median nerve SEP under deep hypothermia is described in a patient undergoing intracranial giant aneurysm surgery. The P14 potential was recorded from Fz-Pgz (front to nasopharynx).
  
  
  RESULTS
  At a body core temperature of less than 17 degrees C, P14 showed a bilobed splitting that was reversible with rewarming. A comparison with latencies of other subcortical potentials of presynaptic and postsynaptic origin, recorded at the neck, speaks in favor of a presynaptic generation of the first P14 wave and a postsynaptic origin of the latter P14 wave.
  
  
  CONCLUSIONS
  Deep hypothermia may separate presynaptic and postsynaptic electric activity of evoked potentials that overlap at normal body temperature. Such possible phenomena must be kept in mind to correctly interprete monitoring data at very low body temperatures and may help in better understanding the generation of different SEP components.
authors.affiliation: Neurochirurgische Universititsklinik Johannes Gutenberg-Universität, Mainz, Germany. wagner@nc.klinik.uni-mainz.de
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Wagner
mesh_terms: D000328:Adult; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced; D008475:Median Nerve / Q000502:physiology*; D016343:Monitoring, Intraoperative; D008991:Monitoring, Physiologic