title: Coronary artery spasm associated with a moderately severe atherosclerotic stenosis in the proximal LAD.
abstract: Treatment of coronary artery spasm can be difficult; up to 25% of patients continue to have episodes of chest pain despite maximal therapy with calcium antagonists and nitrates. We describe the case of a 42-year-old female with severe coronary artery spasm associated with a moderately severe atherosclerotic stenosis of the proximal left anterior descending coronary artery. We discuss the diagnostic value of intravascular ultrasound and treatment options for spasm associated with atherosclerotic plaques.
authors.affiliation: Cardiovascular Research Foundation, Lenox Hill Heart and Vascular Institute, New York, New York 10022, USA.
authors.forename: Dale T
authors.initials: DT
authors.lastname: Ashby
authors.forename: Gerard
authors.initials: G
authors.lastname: Conditt
authors.forename: Makoto
authors.initials: M
authors.lastname: Hirose
authors.forename: George
authors.initials: G
authors.lastname: Dangas
mesh_terms: D000328:Adult; D001241:Aspirin / Q000008:administration & dosage; D000069059:Atorvastatin; D006328:Cardiac Catheterization / Q000379:methods; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D023921:Coronary Stenosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003329:Coronary Vasospasm / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D004110:Diltiazem / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004562:Electrocardiography / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006538:Heptanoic Acids / Q000008:administration & dosage; D006801:Humans; D007547:Isosorbide / Q000008:administration & dosage; D011758:Pyrroles / Q000008:administration & dosage; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods*
chemical_list: D006538:Heptanoic Acids; D011758:Pyrroles; D000069059:Atorvastatin; D004110:Diltiazem; D001241:Aspirin; D007547:Isosorbide