Plasmodium falciparum virulence determinants unveiled.
The human malaria parasite Plasmodium falciparum, one of the world's most devastating pathogens, has an astonishing array of sequences and genes that play key roles in pathogenesis and immune evasion. We must understand the functions of these elements if the chronicity and unpredictable virulence of Plasmodium is to be explained.
Crabb
Brendan S
BS
Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia. crabb@wehi.edu.au
Cowman
Alan F
AF
D000818:Animals; D006801:Humans; D010963:Plasmodium falciparum / Q000235:genetics / Q000472:pathogenicity*; D014774:Virulence / Q000235:genetics*