title: Adenocarcinoma of the ethmoid sinuses: a case of two primary tumours.
abstract: The authors present a case report of a retired furniture worker who initially presented with a mucin-secreting adenocarcinoma of the right ethmoid sinus. He underwent surgical resection, leaving the nasal septum intact, and topical treatment with 5-fluorouracil. He remained disease free. Three years after his initial presentation he was found to have a left nasal polyp on routine examination. This subsequently proved to be a second primary adenocarcinoma. A review of the literature has not shown any other cases of a second primary adenocarcinoma of the ethmoid sinuses.
authors.affiliation: Department of Otolaryngology, Wycombe General Hospital, High Wycombe, UK.
authors.forename: A D
authors.initials: AD
authors.lastname: Mace
authors.forename: A M
authors.initials: AM
authors.lastname: Lale
authors.forename: J W R
authors.initials: JW
authors.lastname: Capper
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000601:surgery*; D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005005:Ethmoid Sinus; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009298:Nasal Polyps / Q000175:diagnosis*; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D010255:Paranasal Sinus Neoplasms / Q000188:drug therapy / Q000601:surgery*
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil