title: Isolation and characterization of a human novel RAB (RAB39B) gene.
abstract: Rab proteins are small-molecular-weight GTPases that control vesicular trafficking in eukaryotic cells. During the large-scale sequencing analysis of a human fetal brain cDNA library, we isolated a cDNA clone encoding a novel Rab protein, which showed 74.2% identity with previously isolated Rab39A at the amino acid level. RAB39B was expressed in a variety of human tissues and located in human chromosome Xq28. It consisted of two exons spanning 3764 bp of human genomic DNA.
authors.affiliation: State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai, P.R. China.
authors.forename: H
authors.initials: H
authors.lastname: Cheng
authors.forename: Y
authors.initials: Y
authors.lastname: Ma
authors.forename: X
authors.initials: X
authors.lastname: Ni
authors.forename: M
authors.initials: M
authors.lastname: Jiang
authors.forename: L
authors.initials: L
authors.lastname: Guo
authors.forename: K
authors.initials: K
authors.lastname: Ying
authors.forename: Y
authors.initials: Y
authors.lastname: Xie
authors.forename: Y
authors.initials: Y
authors.lastname: Mao
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D041321:Chromosomes, Human, X / Q000235:genetics; D018076:DNA, Complementary / Q000235:genetics / Q000302:isolation & purification; D005091:Exons; D005260:Female; D015723:Gene Library; D011905:Genes, ras; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D011247:Pregnancy; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D014018:Tissue Distribution; D020691:rab GTP-Binding Proteins / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; D012333:RNA, Messenger; D020691:rab GTP-Binding Proteins