title: Mesoderm layer and fibrous support tissues essential for embryological differentiation.
abstract: Of the three germ layers, the mesoderm layer is the first to differentiate from the blastula and continues to lead the embryological differentiation while initiating the secretion of antagonistic duplication and maturation factors. After differentiation and while maintaining the secretion of duplication and maturation factors, the fibrous tissues that differentiated from mesoderm play an essential role in regulating the physio-mitotic conditions of functional tissues found in all histological organizations. Accordingly, some defects in mitotic interaction between the fibrous and functional tissues organized into structural units may give rise to various diseases such as carcinoma, sarcoma, leukemia, and fibro-multiplastic, myo-atrophic and neuroatrophic diseases. This defect in mitosis suggests the most important step in achieving eradication of these diseases.
authors.affiliation: Hirata Hospital, Nippon, Kochi, Japan. hphirata@mb.inforyoma.or.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Hirata
authors.forename: S
authors.initials: S
authors.lastname: Hirata
mesh_terms: D036703:Blastula / Q000166:cytology / Q000502:physiology; D002454:Cell Differentiation; D002455:Cell Division; D005314:Embryonic and Fetal Development / Q000502:physiology*; D006801:Humans; D008648:Mesoderm / Q000166:cytology* / Q000502:physiology*; D008954:Models, Biological