Neuropeptides and chromogranins: session overview.
In large dense core vesicles, also referred to as chromaffin granules in adrenomedullary chromaffin cells, transmitters or hormones are stored together with neuropeptides and chromogranins. For most neuropeptides, functions have been established and new findings on their secretion, receptors, and synthesis regulation are reported. The functions of chromogranins are less clear, and possible roles as peptide precursors, Ca(2+) regulators, inducers of secretory granule biogenesis, and as nuclear constituents are discussed.
Laslop
Andrea
A
Department of Pharmacology, University of Innsbruck, Peter-Mayr Strasse 1A, A-6020 Innsbruck, Austria. andrea.laslop@uibk.ac.at
Mahata
Sushil K
SK
D000818:Animals; D002118:Calcium / Q000378:metabolism; D019439:Chromaffin Cells / Q000378:metabolism*; D002864:Chromogranins / Q000502:physiology*; D009479:Neuropeptides / Q000502:physiology*; D010455:Peptides / Q000737:chemistry; D013997:Time Factors
D002864:Chromogranins; D009479:Neuropeptides; D010455:Peptides; D002118:Calcium