title: Breast MR imaging in women at increased lifetime risk of breast cancer: clinical system for computerized assessment of breast lesions initial results.
abstract: The authors developed a clinical system for computerized delineation, rating, and classification of breast lesions depicted in contrast material-enhanced magnetic resonance images obtained in women with increased lifetime risk of breast cancer. Initial results showed negative predictive values above 98% at 50% positive predictive value with negligible interoperator differences. The system demonstrated potential to help exclude malignancy with high confidence and reproducibility with a positive predictive value that is acceptable in screening.
authors.affiliation: Departments of Radiology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.
authors.forename: Kenneth G A
authors.initials: KG
authors.lastname: Gilhuijs
authors.forename: Eline E
authors.initials: EE
authors.lastname: Deurloo
authors.forename: Sara H
authors.initials: SH
authors.lastname: Muller
authors.forename: Johannes L
authors.initials: JL
authors.lastname: Peterse
authors.forename: Leo J
authors.initials: LJ
authors.lastname: Schultze Kool
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D003287:Contrast Media; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008403:Mass Screening; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012307:Risk Factors
chemical_list: D003287:Contrast Media