Bilateral spike-and-wave discharges in a hemi-deafferented cortex.
We studied a patient with a history of absence attacks in childhood in whom an absence status with bilateral spike-and-wave discharges developed after a top-of-the-basilar syndrome. Surprisingly, even though the ischemic lesion involved the left thalamus alone, spike-and-wave discharges were recorded from the two hemispheres. Three days after antiepileptic treatment (sodium valproate 500mg 3 times a day) began, electroenceplalographic recordings and consciousness became normal.
Inghilleri
M
M
Department of Neurological Sciences, University of Rome, Rome, Italy. maurizio.inghilleri@uniroma1.it
Clemenzi
A
A
Conte
A
A
Frasca
V
V
Manfredi
M
M
D000200:Action Potentials / Q000502:physiology*; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000503:physiopathology*; D004569:Electroencephalography / Q000379:methods*; D004832:Epilepsy, Absence / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D009778:Occipital Lobe / Q000473:pathology
D000927:Anticonvulsants