Highly oxygenated triterpenes from the roots of Atropa acuminata.
Two new oleanane triterpenes; 2alpha,3alpha,24-trihydroxyolean-12-ene-28,30-dioic acid ([structure: see text]) and 2alpha,3alpha,24,28-tetrahydroxyolean-12-ene ([structure: see text]) have been isolated from the roots of Atropa acuminata. Anti-oxidant p-hydroxyphenethyl trans-ferulate ([structure: see text]), beta-sitosterol-3-O-beta-D-glucopyranoside ([structure: see text]) and oleanolic acid ([structure: see text]) have also been reported for the first time from this species. The structures were determined by spectroscopic studies including 2D-NMR.
Mehmood
Arshad
A
International Center for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
Malik
Abdul
A
Anis
Itrat
I
Khan
Pir Mohammad
PM
Riaz
Muhammad
M
Makhmoor
Talat
T
Choudhary
M Iqbal
MI
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D032282:Atropa / Q000737:chemistry*; D003373:Coumaric Acids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010154:Pakistan; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C472602:2,3,24,28-tetrahydroxyolean-12-ene; C472601:2,3,24-trihydroxyolean-12-ene-28,30-dioic acid; D000975:Antioxidants; D003373:Coumaric Acids; D005960:Glucosides; D012855:Sitosterols; D014315:Triterpenes; C472603:hydroxyphenethylferulate; C472604:sitosterol-3-O-glucopyranoside; D009828:Oleanolic Acid