title: [Study of the real situation of improvement by Zopiclone in treatment of insomnia among persons working during night shifts].
abstract: We investigated the effect of adapted management of sleep on the duration and quality of sleep in shift workers working the night shift. Twenty-nine shift workers suffering from insomnia were included and treated with zopiclone (7.5mg/day) or placebo according to a random double-blind protocol. Patients completed a sleep diary and a wrist actigraph was used to evaluate episodes of rest/activity. A self-administered subjective sleep questionnaire was filled out just after awakening. Zopicone was found to increase the duration of sleep significantly (p<0.05) over the baseline duration after the first and second night on duty. Subjective estimation of sleep was better in patients taking zopiclone who exhibited a smaller number of shorter awakening episodes.
  
  
  CONCLUSIONS
  zopiclone improves the quality and duration of sleep in shift workers suffering from insomnia.
authors.affiliation: Hôpital Raymond Poincaré, AP-HP, Université Paris Ouest, Garches.
authors.forename: M A
authors.initials: MA
authors.lastname: Quera-Salva
authors.forename: P
authors.initials: P
authors.lastname: Philip
authors.forename: J
authors.initials: J
authors.lastname: Taillard
authors.forename: R
authors.initials: R
authors.lastname: Letrequeser
authors.forename: H
authors.initials: H
authors.lastname: Allain
authors.forename: S
authors.initials: S
authors.lastname: Garcia-Acosta
authors.forename: I
authors.initials: I
authors.lastname: Kermad
authors.forename: J
authors.initials: J
authors.lastname: Krieger
authors.forename: M
authors.initials: M
authors.lastname: Dib
mesh_terms: D000328:Adult; D053961:Azabicyclo Compounds; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000188:drug therapy*; D010879:Piperazines / Q000627:therapeutic use*; D020178:Sleep Disorders, Circadian Rhythm / Q000188:drug therapy*; D014851:Wakefulness
chemical_list: D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone