Transient MR signal changes in the splenium of the corpus callosum in rotavirus encephalopathy: value of diffusion-weighted imaging.
The authors report serial brain MR findings from a 2-year-old girl with rotavirus encephalopathy. The lesion in the splenium of the corpus callosum showed restricted proton diffusion, suggesting local cytotoxic edema. Diffusion-weighted images demonstrated the lesion more conspicuously than other techniques, such as fluid-attenuated inversion-recovery and T1- and T2-weighted images. The findings were reversible on follow-up MRI obtained 4 days later. Diffusion-weighted MRI is a potentially useful method for detecting early changes of rotavirus encephalopathy, although the mechanism of the restricted diffusion is not clearly identified.
Kobata
Ritsuyo
R
Department of Pediatrics, Faculty of Medicine, Fukui Medical University, Fukui 910-1193, Japan.
Tsukahara
Hirokazu
H
Nakai
Akio
A
Tanizawa
Akihiko
A
Ishimori
Yoshiyuki
Y
Kawamura
Yasutaka
Y
Ushijima
Hiroshi
H
Mayumi
Mitsufumi
M
D002675:Child, Preschool; D003337:Corpus Callosum / Q000473:pathology*; D018792:Encephalitis, Viral / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012400:Rotavirus Infections / Q000473:pathology*