title: Hemolytic uremic syndrome in metastatic adenocarcinoma of the prostate.
abstract: The authors report 4 cases of hemolytic uremic syndrome (HUS) in association with metastatic adenocarcinoma of the prostate. All patients were treated with hemodialysis with or without plasma exchange. All made a good recovery. In one patient the diagnosis of prostatic adenocarcinoma was first made after presentation with HUS. The authors suggest that this condition may be more common than previously thought and, that in view of its good prognosis, may be a separate entity to chemotherapy-associated HUS in patients with cancer. It also is recommended that adult male patients presenting with unexplained HUS should have clinical assessment of their prostate and measurement of prostate specific antigen.
authors.affiliation: Richard Bright Renal Unit and the Academic Renal Unit, Southmead Hospital, Westbury on Trym, Bristol, England.
authors.forename: Sarah
authors.initials: S
authors.lastname: Mungall
authors.forename: Peter
authors.initials: P
authors.lastname: Mathieson
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000150:complications* / Q000188:drug therapy / Q000556:secondary*; D000368:Aged; D000369:Aged, 80 and over; D006463:Hemolytic-Uremic Syndrome / Q000097:blood / Q000139:chemically induced / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D011467:Prostate / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000150:complications* / Q000188:drug therapy / Q000556:secondary*; D006435:Renal Dialysis / Q000379:methods
chemical_list: D017430:Prostate-Specific Antigen