title: Prevalence of clinical isolates of Escherichia coli producing inhibitor-resistant beta-lactamases at a University Hospital in Barcelona, Spain, over a 3-year period.
abstract: About 7% of 7,252 nonduplicated clinical Escherichia coli strains from a Spanish hospital showed reduced susceptibility to amoxicillin-clavulanate. Of these, 0.37% produced the IRTs TEM-30, TEM-31, TEM-33, TEM-34, TEM-37, TEM-40, TEM-51, and TEM-54; 5.3% were probable class C beta-lactamase overproducers; 0.8% were probable TEM-1 hyperproducers; 0.18% produced OXA-30; 0.15% overexpressed SHV-1; and 0.03% produced a PSE-1 enzyme.
authors.affiliation: Departament de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma 08025 Barcelona, Spain. emiro@hsp.santpau.es
authors.forename: Elisenda
authors.initials: E
authors.lastname: Miró
authors.forename: Ferran
authors.initials: F
authors.lastname: Navarro
authors.forename: Beatriz
authors.initials: B
authors.lastname: Mirelis
authors.forename: Montserrat
authors.initials: M
authors.lastname: Sabaté
authors.forename: Alba
authors.initials: A
authors.lastname: Rivera
authors.forename: Pere
authors.initials: P
authors.lastname: Coll
authors.forename: Guillem
authors.initials: G
authors.lastname: Prats
mesh_terms: D019980:Amoxicillin-Potassium Clavulanate Combination / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D010641:Phenotype; D013030:Spain; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D019980:Amoxicillin-Potassium Clavulanate Combination; D001618:beta-Lactamases