Pharmaceutical and biotechnological aerosols for cystic fibrosis therapy.
This review addresses different aerosol therapies used to treat the underlying cause and symptoms of cystic fibrosis (CF) during the past two decades. A summary of the current methods of aerosol delivery and suggestions that may improve the efficacy of the current treatments are provided.
Garcia-Contreras
Lucila
L
Division of Drug Delivery and Disposition, School of Pharmacy, Beard Hall, CB #7360 University of North Carolina, Chapel Hill, NC 27599, USA. lgarciac@email.unc.edu
Hickey
Anthony J
AJ
D000280:Administration, Inhalation; D000336:Aerosols; D003550:Cystic Fibrosis / Q000188:drug therapy / Q000628:therapy*; D004355:Drug Stability; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000008:administration & dosage; D006801:Humans; D009330:Nebulizers and Vaporizers; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry*
D000336:Aerosols; D004364:Pharmaceutical Preparations