title: Cytokins in the pathogenesis of astrakhan spotted Fever and North Asian scrub typhus: problems of immunocorrection.
abstract: Comparative study of interleukin-1 and tumor necrosis factor production under conditions of experimental rickettsial infection caused by agents of Astrakhan spotted fever and North Asian scrub typhus showed that therapy with galavit reduced manifestations of the disease, decreased mortality of experimental animals, and decreased the concentrations of interleukin-1 and tumor necrosis factor to normal values.
authors.affiliation: Institute of Immunopathology, Russian Academy of Natural Sciences, Moscow.
authors.forename: M V
authors.initials: MV
authors.lastname: Nelyubov
mesh_terms: D000818:Animals; D002642:Chick Embryo; D007375:Interleukin-1 / Q000502:physiology*; D051379:Mice; D012282:Rickettsia Infections / Q000276:immunology / Q000503:physiopathology*; D012612:Scrub Typhus / Q000276:immunology / Q000503:physiopathology*; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology*
chemical_list: D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha