title: Microcystic adnexal carcinoma of the breast: a very rare breast skin tumor.
abstract: BACKGROUND
  Microcystic adnexal carcinoma is a rare, slowly progressing, malignant tumor of sweat gland origin.
  
  
  OBJECTIVE
  A case of microcystic adnexal carcinoma of the breast with a history of 20 years is presented.
  
  
  METHODS
  On initial examination, the ulcerative cutaneous mass was fixed to the underlying breast tissue and chest wall. Both the macroscopic appearance of the tumor and its location suggested a glandular breast carcinoma. However, an incisional biopsy revealed the nature of the tumor as microcystic adnexal carcinoma of the breast skin. Following the diagnosis, a wide excision of the tumor was carried out for the final treatment.
  
  
  RESULTS
  To our knowledge this is the first case of microcystic adnexal carcinoma arising in the breast skin presented in the literature.
  
  
  CONCLUSIONS
  This case demonstrates that microcystic adnexal carcinoma can occur on the breast skin and should be treated with wide excision due to its locally aggressive behavior.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Gazi University, Medical Faculty, Ankara, Turkey. ryavuzer@hotmail.com
authors.forename: Reha
authors.initials: R
authors.lastname: Yavuzer
authors.forename: Melda
authors.initials: M
authors.lastname: Boyaci
authors.forename: Alper
authors.initials: A
authors.lastname: Sari
authors.forename: Omür
authors.initials: O
authors.lastname: Ataoğlu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018280:Carcinoma, Skin Appendage / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D053552:Keratin-7; D007633:Keratins / Q000378:metabolism*; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D013544:Sweat Gland Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: C507497:KRT7 protein, human; D053552:Keratin-7; D007633:Keratins