title: Complexation of VEGF with bevacizumab decreases VEGF clearance in rats.
authors.affiliation: hsei@gene.com
authors.forename: Vanessa
authors.initials: V
authors.lastname: Hsei
authors.forename: Geralyn G
authors.initials: GG
authors.lastname: Deguzman
authors.forename: Alison
authors.initials: A
authors.lastname: Nixon
authors.forename: Jacques
authors.initials: J
authors.lastname: Gaudreault
mesh_terms: D043925:Angiogenesis Inducing Agents / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000378:metabolism*; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D002626:Chemistry, Pharmaceutical; D005260:Female; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D042461:Vascular Endothelial Growth Factor A
chemical_list: D043925:Angiogenesis Inducing Agents; D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D000068258:Bevacizumab