title: Inhibiting 5-fluorouracil breakdown: a broken down approach to 5-fluorouracil modulation.
authors.affiliation: Biological Sciences Division, University of Chicago, IL, USA.
authors.forename: Richard L
authors.initials: RL
authors.lastname: Schilsky
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000378:metabolism* / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000188:drug therapy / Q000378:metabolism*; D042943:Dihydrouracil Dehydrogenase (NADP); D004357:Drug Synergism; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D005472:Fluorouracil / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D010088:Oxidoreductases / Q000378:metabolism*; D014498:Uracil / Q000031:analogs & derivatives* / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004791:Enzyme Inhibitors; C073482:eniluracil; D014498:Uracil; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil