TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus.
Mossy fiber (MF) synapses are key stations for flow of information through the hippocampal formation. A major component of the output of the MF system is directed towards inhibitory interneurons. Recent studies have revealed that the functional properties of MF-interneuron synapses differ substantially from those of MF-CA3 pyramidal neuron synapses. Mossy-fiber-interneuron synapses in the stratum lucidum represent a continuum of functional subtypes, in which the subunit composition of postsynaptic AMPA receptors and NMDA receptors appears to be regulated in a coordinated manner.
Bischofberger
Josef
J
Physiologisches Institut, Universität Freiburg, Hermann-Herder-Str. 7, Germany.
Jonas
Peter
P
D000818:Animals; D007395:Interneurons / Q000502:physiology*; D019599:Mossy Fibers, Hippocampal / Q000502:physiology*; D017966:Pyramidal Cells / Q000502:physiology; D018091:Receptors, AMPA / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*
D018091:Receptors, AMPA; D016194:Receptors, N-Methyl-D-Aspartate