title: Human demographic history: refining the recent African origin model.
abstract: Recent studies of large portions of the human genome support a recent origin of modern humans from an African stock after a bottleneck of moderate size followed by a range expansion out of Africa. Under this simple scenario, patterns of molecular diversity suggest that balancing selection could be more prevalent than positive selection in coding regions.
authors.affiliation: Computational and Molecular Population Genetics (CMPG) Lab, Zoological Institute, University of Bern, Baltzerstrasse 6, 3012, Bern, Switzerland. Laurent.Exoffier@zoo.unibe.ch
authors.forename: Laurent
authors.initials: L
authors.lastname: Excoffier
mesh_terms: D000349:Africa; D019143:Evolution, Molecular; D014644:Genetic Variation; D005828:Genetics, Population; D015894:Genome, Human; D006801:Humans; D015810:Linkage Disequilibrium; D011157:Population Dynamics; D012641:Selection, Genetic