title: Squamocin-O(1) and squamocin-O(2), new adjacent bis-tetrahydrofuran acetogenins from the seeds of Annona squamosa.
abstract: Two bis-tetrahydrofuran acetogenins, squamocin-O(1) (1) and squamocin-O(2) (2), were isolated from a MeOH extract of seeds of Annona squamosa L. Their structures were determined by spectral means including precursor-ion scanning mass spectral analysis for their aminal derivatives. The configurations at the oxymethine chiral centers were assigned as 12R,15R,16R,19R,20R,23R,24S,28S,36S for 1 and 12S,15R,16R,19R,20R,23R,24S, 28S,36S for 2, based on 1H NMR analysis of their Mosher's ester derivatives and CD data.
authors.affiliation: National Institute for Agro-Environmental Sciences, Kan-nondai, Tsukuba, Ibaraki 305-8604, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Araya
authors.forename: Mahendra
authors.initials: M
authors.lastname: Sahai
authors.forename: Shubhra
authors.initials: S
authors.lastname: Singh
authors.forename: Ajit Kumar
authors.initials: AK
authors.lastname: Singh
authors.forename: Mitsuzi
authors.initials: M
authors.lastname: Yoshida
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Hara
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Fujimoto
mesh_terms: D031041:Annona / Q000737:chemistry*; D005663:Furans / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D012639:Seeds / Q000737:chemistry*
chemical_list: D005663:Furans; C473730:squamocin-O(1); C473729:squamocin-O(2)