Hemopoietic and lymphoid organs in AKR/JY mice with thymic lymphoma.
Cytological and histological studies of the thymus, bone marrow, peripheral blood, spleen, and lymph nodes in 6-9-month-old AKR/JY mice showed that the risk of thymic lymphoma in these animals increased with age. Generalization of the tumor process was observed in mice aged over 8 months and first involved the spleen, then the lymph nodes, bone marrow, and liver. A case of primary lymphoma in the spleen was detected.
Karpova
G V
GV
Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences.
Fomina
T I
TI
Abramova
E V
EV
Bel'skaya
N V
NV
Trofimova
E S
ES
Perel'muter
V M
VM
D000818:Animals; D001835:Body Weight; D005260:Female; D006412:Hematopoietic Stem Cells / Q000378:metabolism* / Q000473:pathology; D006413:Hematopoietic System / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008223:Lymphoma / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D009929:Organ Size; D013160:Splenic Neoplasms / Q000235:genetics / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology; D013953:Thymus Neoplasms / Q000235:genetics* / Q000473:pathology; D013997:Time Factors