title: Quantitative assessment of skin layers absorption and skin reflectance spectra simulation in the visible and near-infrared spectral regions.
abstract: We have simulated diffuse reflectance spectra of skin by assuming a wavelength-independent scattering coefficient for the different skin tissues and using the known wavelength dependence of the absorption coefficient of oxy- and deoxyhaemoglobin and water. A stochastic Monte Carlo method is used to convert the wavelength-dependent absorption coefficient and wavelength-independent scattering coefficient into reflected intensity. The absorption properties of skin tissues in the visible and near-infrared spectral regions are estimated by taking into account the spatial distribution of blood vessels, water and melanin content within distinct anatomical layers. The geometrical peculiarities of skin histological structure, degree of blood oxygenation and the haematocrit index are also taken into account. We demonstrate that when the model is supplied with reasonable physical and structural parameters of skin, the results of the simulation agree reasonably well with the results of in vivo measurements of skin spectra.
authors.affiliation: School of Engineering, Cranfield University, Cranfield, MK43 0AL, UK. i.meglinski@cranfield.ac.uk
authors.forename: Igor V
authors.initials: IV
authors.lastname: Meglinski
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Matcher
mesh_terms: D000042:Absorption; D000465:Algorithms; D006801:Humans; D008027:Light; D008954:Models, Biological; D009010:Monte Carlo Method; D055095:Optics and Photonics; D012867:Skin / Q000098:blood supply*; D012879:Skin Physiological Phenomena / Q000528:radiation effects*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*