title: Migraine: preventive treatment.
abstract: Preventive treatment is designed to decrease headache frequency. It should be used if headaches are too frequent, disabling, or associated with worrisome neurological features or if acute treatment is overused or ineffective. The chosen drug should be given an adequate trial in the absence of interfering medications. Choose a drug based on its efficacy, adverse event profile, and the presence of coexistent conditions.
authors.affiliation: Jefferson Headache Center, Thomas Jefferson University Hospital, Philadelphia, PA, USA. stephen.silberstein@mail.tju.edu
authors.forename: S D
authors.initials: SD
authors.lastname: Silberstein
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy / Q000517:prevention & control*; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use; D008517:Phytotherapy; D012256:Riboflavin / Q000627:therapeutic use; D012702:Serotonin Antagonists / Q000627:therapeutic use; D020903:Tanacetum parthenium
chemical_list: D000319:Adrenergic beta-Antagonists; D000927:Anticonvulsants; D000928:Antidepressive Agents; D002121:Calcium Channel Blockers; D008996:Monoamine Oxidase Inhibitors; D012702:Serotonin Antagonists; D012256:Riboflavin