Constituents and biological activities from Muehlenbeckia hastulata.
Muehlenbeckia hastulata (J. E.Sm.) Johnst. used mainly for its abortive properties was found active for oxytoxic and analgesic activities in a biological activity screening (oxytoxic, analgesic, antimicrobial, cytotoxic and xanthine oxidase assay). Epicatechin, emodin-8-glycoside and rutin were isolated from the aerial part and the root of the plant.
Erazo
Silvia
S
Department of Pharmacological and Toxicological Chemistry, School of Chemical and Pharmaceutical Sciences, University of Chile, Santiago. serazo@uchile.cl
Muñoz
Orlando
O
García
Rubén
R
Lemus
Igor
I
Backhouse
Nadine
N
Negrete
Rosa
R
San Feliciano
Arturo
A
Delporte
Carla
C
D000700:Analgesics / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D002470:Cell Survival / Q000187:drug effects; D002677:Chile; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D019684:Magnoliopsida / Q000737:chemistry*; D051379:Mice; D008826:Microbial Sensitivity Tests; D010146:Pain; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured; D014599:Uterus / Q000187:drug effects / Q000502:physiology
D000700:Analgesics; D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts