title: Biocompatibility tests on the intraocular vision aid IOVA.
abstract: Intraocular miniaturized image transmission systems are developed to restore vision in patients with irreversible destruction of the anterior ocular segment (i.e. chemical burns, explosion trauma, trachoma) and high risk for corneal transplantation, provided that the posterior ocular segment is intact. To ensure safety of such a device biocompatibility tests were conducted. In the present study the effects of light and temperature in various intensities and the toxicity of the implanted materials on neural function in the rabbit retina in-vivo was investigated. All tests give encouraging results concerning the feasibility of intraocular miniaturized image transmission systems.
authors.affiliation: Dept. of Ophthalmology, University of Cologne, Germany. N.Alteheld@uni-koeln.de
authors.forename: N
authors.initials: N
authors.lastname: Alteheld
authors.forename: M A
authors.initials: MA
authors.lastname: Vobig
authors.forename: G
authors.initials: G
authors.lastname: Marzella
authors.forename: H
authors.initials: H
authors.lastname: Berk
authors.forename: R
authors.initials: R
authors.lastname: Shojaei
authors.forename: U
authors.initials: U
authors.lastname: Heimann
authors.forename: S
authors.initials: S
authors.lastname: Held
authors.forename: P
authors.initials: P
authors.lastname: Walter
authors.forename: K U
authors.initials: KU
authors.lastname: Bartz-Schmidt
mesh_terms: D000818:Animals; D003318:Corneal Opacity / Q000503:physiopathology / Q000534:rehabilitation*; D004867:Equipment Design; D006801:Humans; D008422:Materials Testing; D008838:Microcomputers; D008904:Miniaturization / Q000295:instrumentation*; D019736:Prostheses and Implants; D011817:Rabbits; D012160:Retina / Q000503:physiopathology; D012682:Sensory Aids