[Hypersexuality during use of levodopa].
A 71-year-old single male who was being treated for Parkinson's disease with levodopa, had several episodes of hypersexual behaviour. Home care was terminated for this reason. Family members in particular had problems with his behaviour. It transpired that he was taking more levodopa than prescribed. After explaining the side-effect to the patient and after a special medication box was purchased which could be filled by the family, the patient's hypersexuality disappeared without deterioration of Parkinson's disease. Hypersexuality is a known, though not frequently recognised side-effect of dopaminergic anti-Parkinson therapy, especially levodopa. This side-effect is not life-threatening, but can have an enormous impact on the quality of life of the patient, his or her partner and environment. The mechanism is probably related to the pharmacological action of dopamine.
van Deelen
R A J
RA
Afd. Geriatrie, TweeSteden Ziekenhuis, Postbus 90.107, 5000 LA Tilburg.
Rommers
M K
MK
Eerenberg
J G
JG
Egberts
A C G
AC
D000368:Aged; D000978:Antiparkinson Agents / Q000009:adverse effects* / Q000627:therapeutic use; D015259:Dopamine Agents / Q000009:adverse effects* / Q000627:therapeutic use; D062787:Drug Overdose; D006801:Humans; D007980:Levodopa / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy*; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced*
D000978:Antiparkinson Agents; D015259:Dopamine Agents; D007980:Levodopa