title: Biochemical changes in the sublingual and submandibular glands after interruption of chorda tympani.
abstract: The left chorda tympani nerve was interrupted through meatus acusticus externus in ten dogs. In total, 40 dog salivary glands (20 submandibular and 20 sublingual) innervated via chorda tympani were examined. Twenty glands (10 submandibular and 10 sublingual) on the left side were deprived of parasympathetic innervation by chordectomy, whereas contraleteral glands, on the right side, served as controls. Biochemical analysis showed that the interruption of chorda tympani did not cause any significant changes in the concentrations of eight enzymes investigated, i.e. lactate dehydrogenase, alkaline phosphatase, acid phosphatase, amylase, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase and creatine kinase. There were no significant changes in the concentrations of most important extracellular ions (sodium, potassium, chloride and phosphorus) in the right glands, but the loss of parasympathetic innervation in the left glands was found to cause a statistically significant decrease in the concentration of potassium as intracellular cation and of phosphorus as extracellular anion.
authors.affiliation: ENT Department, School of Medicine, University of Zagreb, Department of Anatomy, Histology and Embriology, School of Veterinary Medicine. sbranica@mef.hr
authors.forename: Srećko
authors.initials: S
authors.lastname: Branica
authors.forename: Nikola
authors.initials: N
authors.lastname: Sprem
authors.forename: Damir
authors.initials: D
authors.lastname: Mihelić
authors.forename: Mladen
authors.initials: M
authors.lastname: Zobundzija
authors.forename: Dubravka
authors.initials: D
authors.lastname: Cvoriscec
authors.forename: Melita
authors.initials: M
authors.lastname: Cacić
authors.forename: Krsto
authors.initials: K
authors.lastname: Dawidowsky
mesh_terms: D000818:Animals; D002814:Chorda Tympani Nerve / Q000502:physiology* / Q000601:surgery; D004285:Dogs; D004573:Electrolytes / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism; D013361:Sublingual Gland / Q000378:metabolism*; D013363:Submandibular Gland / Q000378:metabolism*
chemical_list: D004573:Electrolytes; D004798:Enzymes