Prooxidant effects of nitrofurantoin.
We studied the possibility of using prooxidant effects of nitrofurantoin (furadonin) for stimulation of the natural antioxidant systems for preventing myocardial damage after coronary occlusion. A pronounced cardioprotective effect of the drug was observed.
Novikov
O O
OO
Pokrovskii
M V
MV
Konovalenko
A B
AB
D000818:Animals; D002316:Cardiotonic Agents / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D009582:Nitrofurantoin / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D017382:Reactive Oxygen Species / Q000494:pharmacology*
D002316:Cardiotonic Agents; D017382:Reactive Oxygen Species; D009582:Nitrofurantoin