title: Brief chewing of Garcinia manii stick reverses reduced saliva pH after a glucose rinse.
abstract: BACKGROUND
  A popular variety of wood, pieces of which are chewed as an oral hygiene practice in Southern Ghana, was tested for its capacity to reverse experimentally lowered pH of saliva. This was done to determine whether (Garcinia manii) stick-chewing neutralizes acidogenic challenge to teeth, and thereby potentially affords dental caries prevention benefit.
  
  
  METHODS
  Seventy-two volunteer medical students gave (baseline) saliva samples by spitting 3-4 times into a 25 ml conical flask. They then rinsed their mouths with a five-percent aqueous solution of glucose. Subsequent to the glucose rinse, half of the subjects (chewers), pre-selected by drawing lots, chewed a popular chewing stick Garcinia manii for five minutes, while the other half (controls) did not. The pH of saliva samples given by the volunteers at various time intervals was measured using a Kent EIL 7020 pH meter, and the results were analysed by the Analysis of Variance (Anova) method.
  
  
  RESULTS
  As expected, saliva pH was reduced in both groups after the glucose rinse, but increased significantly faster in stick chewers compared with controls.
  
  
  CONCLUSIONS
  It is suggested from this study that brief (Garcina manii) stick-chewing confers a caries prevention/control benefit by reversing acidogenic challenge to teeth.
authors.affiliation: Department of Anatomy, University of Ghana Medical School, Accra, Ghana. anatomy@idngh.com
authors.forename: Frederick Kwaku
authors.initials: FK
authors.lastname: Addai
authors.forename: Isaac Kwasi K
authors.initials: IK
authors.lastname: Nuamah
authors.forename: Grace E
authors.initials: GE
authors.lastname: Parkins
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D005260:Female; D029760:Garcinia; D005947:Glucose / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D013997:Time Factors; D014099:Toothbrushing / Q000295:instrumentation
chemical_list: D010936:Plant Extracts; D005947:Glucose