Chemotaxis and cell differentiation in Dictyostelium.
Dictyostelium genome sequencing predicts an unexpectedly large number of genes. Many are absent from yeast but present in animals and presumably support cellular abilities not found in yeast. Prominent amongst these abilities is chemotaxis, where great strides are being made in understanding how cells orient in a gradient and mobilise their cytoskeleton for movement. In multicellular development, a regulatory scheme for proportioning prespore and prestalk-O cells has emerged.
Kay
Robert R
RR
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK. rrk@mrc-lmb.cam.ac.uk
D000818:Animals; D002454:Cell Differentiation / Q000235:genetics / Q000502:physiology*; D002633:Chemotaxis / Q000502:physiology*; D004023:Dictyostelium / Q000166:cytology / Q000235:genetics / Q000502:physiology*; D018503:Genome, Protozoan; D015398:Signal Transduction / Q000502:physiology*; D013170:Spores; D013672:Technology