Using ECG-gated multidetector CT to evaluate global left ventricular myocardial function in patients with coronary artery disease.
OBJECTIVE
Retrospectively ECG-gated three-dimensional volume data from multidetector CT (MDCT) coronary angiography enable image reconstruction of the cardiac cycle in the diastolic and systolic phases. The objective of our study was to investigate the feasibility of determining left ventricular function from MDCT coronary angiography data sets in 22 patients with coronary artery disease and to study the correlation of MDCT results with those of functional data from biplane cineventriculography.


CONCLUSIONS
Multiplanar reformations from three-dimensional MDCT data allowed good delineation of endocardial and epicardial left ventricular contours. In patients evaluated for coronary artery disease, MDCT coronary angiography with retrospective ECG gating provides functional data in an acceptable correlation (r = 0.8; p < 0.05) to biplane cineventriculography.
Juergens
Kai Uwe
KU
Department of Clinical Radiology, University of Muenster, Albert-Schweitzer-Str. 33, D-48149 Muenster, Germany.
Grude
Matthias
M
Fallenberg
Eva Maria
EM
Opitz
Christian
C
Wichter
Thomas
T
Heindel
Walter
W
Fischbach
Roman
R
D000328:Adult; D000368:Aged; D002933:Cineradiography; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004562:Electrocardiography; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013318:Stroke Volume; D014057:Tomography, X-Ray Computed / Q000379:methods; D016277:Ventricular Function, Left