title: Generalised infantile myofibromatosis with intracranial involvement: imaging findings in a newborn.
abstract: Infantile myofibromatosis is a disorder of infancy and early childhood characterised by single or multiple nodular lesions localised to bone, muscle, viscera, subcutaneous tissue or central nervous system. These pseudotumours contain smooth muscle and fibroblasts. The prognosis depends on the amount, as well as location, of the lesions. We present the radiological findings on plain films, US and MRI of a newborn who presented at birth with multiple organ involvement, including the CNS. To our knowledge, the comprehensive imaging features of such severe and multifocal involvement have not previously been reported.
authors.affiliation: Department of Paediatric Radiology, Hôpital Universitaire des Enfants, 6 Avenue Willy Donzé, 1211 Geneva 14, Switzerland. Ispadola@mac.com
authors.forename: Luca
authors.initials: L
authors.lastname: Spadola
authors.forename: Mehrak
authors.initials: M
authors.lastname: Anooshiravani
authors.forename: Yasmine
authors.initials: Y
authors.lastname: Sayegh
authors.forename: Sigrid
authors.initials: S
authors.lastname: Jéquier
authors.forename: Sylviane
authors.initials: S
authors.lastname: Hanquinet
mesh_terms: D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D018224:Myofibromatosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography; D014463:Ultrasonography