title: Participation of peripheral and spinal phosphodiesterases 4 and 5 in inflammatory pain.
authors.affiliation: Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Calz. Tenorios 235, Col. Granjas Coapa, 14330 México, D.F.
authors.forename: Jorge E
authors.initials: JE
authors.lastname: Torres-López
authors.forename: Carlos F
authors.initials: CF
authors.lastname: Argüelles
authors.forename: Vinicio
authors.initials: V
authors.lastname: Granados-Soto
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000502:physiology*; D015106:3',5'-Cyclic-GMP Phosphodiesterases; D000818:Animals; D054703:Cyclic Nucleotide Phosphodiesterases, Type 4; D054706:Cyclic Nucleotide Phosphodiesterases, Type 5; D005260:Female; D005557:Formaldehyde; D007249:Inflammation / Q000150:complications / Q000188:drug therapy* / Q000201:enzymology; D007278:Injections, Spinal; D010146:Pain / Q000188:drug therapy* / Q000201:enzymology / Q000209:etiology; D010147:Pain Measurement / Q000187:drug effects; D010726:Phosphodiesterase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D010727:Phosphoric Diester Hydrolases / Q000502:physiology*; D010879:Piperazines / Q000008:administration & dosage / Q000627:therapeutic use; D011687:Purines; D051381:Rats; D017208:Rats, Wistar; D020889:Rolipram / Q000008:administration & dosage / Q000627:therapeutic use; D000068677:Sildenafil Citrate; D013116:Spinal Cord / Q000201:enzymology*; D013450:Sulfones
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D005557:Formaldehyde; D000068677:Sildenafil Citrate; D010727:Phosphoric Diester Hydrolases; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D054703:Cyclic Nucleotide Phosphodiesterases, Type 4; D015106:3',5'-Cyclic-GMP Phosphodiesterases; D054706:Cyclic Nucleotide Phosphodiesterases, Type 5; C517384:Pde5a protein, rat; D020889:Rolipram