Endocytosis: curvature to the ENTH degree.
Recent work has shown that the protein epsin 1 induces highly curved lipidic structures when added with clathrin to appropriate lipid mixtures. This property may be a critical factor in the 'curvature stress cycle' of membrane trafficking.
Nossal
Ralph
R
National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Zimmerberg
Joshua
J
D033942:Adaptor Proteins, Vesicular Transport; D000818:Animals; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology; D002453:Cell Cycle / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology; D004705:Endocytosis / Q000502:physiology*; D008051:Lipid Bilayers / Q000737:chemistry; D008954:Models, Biological; D009479:Neuropeptides / Q000235:genetics / Q000502:physiology; D013314:Stress, Mechanical; D014162:Transfection; D033921:Vesicular Transport Proteins
D033942:Adaptor Proteins, Vesicular Transport; D002352:Carrier Proteins; D008051:Lipid Bilayers; D009479:Neuropeptides; D033921:Vesicular Transport Proteins; C114154:epsin