title: Neurotrophins and the control of axonal outgrowth.
abstract: The neurotrophins NGF, BDNF, NT-3, and NT-4/5 are well known for their neuron survival-promoting functions. This review focuses upon a less-investigated function of this gene family, namely that of controlling the growth of axons in vivo. Recent evidence is discussed that reveals a definitive requirement for neurotrophin signaling in the elongation of peripheral nerves during embryonic development.
authors.affiliation: Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland. klt@fmi.ch
authors.forename: K L
authors.initials: KL
authors.lastname: Tucker
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology*; D009414:Nerve Growth Factors / Q000378:metabolism*; D009420:Nervous System / Q000254:growth & development
chemical_list: D009414:Nerve Growth Factors