Usefulness of FDG-positron emission tomography in diagnosing peritoneal recurrence of colorectal cancer.
BACKGROUND
Accurate detection of peritoneal recurrence in colorectal cancer remains a diagnostic challenge. We retrospectively examined sensitivity and accuracy of fluorine-18-2-fluoro-deoxy-D-glucose positron emission tomography (FDG-PET) in the diagnosis of peritoneal recurrence.


METHODS
FDG-PET and computed tomography (CT) were performed on 23 patients with colorectal cancer suspected of having a recurrence based on clinical symptoms, a tumor marker (CEA), and so forth. The final diagnosis was compared with the results of FDG-PET and CT.


RESULTS
Peritoneal recurrence was suspected in 6 patients with FDG-PET, and 5 of them were finally diagnosed as recurrences. The sensitivity of FDG-PET was 88% and its diagnostic accuracy was 78%, whereas those of CT were 38% and 44%, respectively. A lesion as small as 15 mm in diameter was diagnosed by FDG-PET.


CONCLUSIONS
FDG-PET is an effective method for diagnosing peritoneal recurrence of colorectal cancer. FDG-PET is expected to become more important for detecting peritoneal recurrence at an early stage.
Tanaka
Tomoharu
T
Department of Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute, Osaka, Japan.
Kawai
Yasuhiro
Y
Kanai
Michiyuki
M
Taki
Yoshiro
Y
Nakamoto
Yuuji
Y
Takabayashi
Arimichi
A
D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18