Past and present attempts to prevent radiocontrast nephropathy.
Radiocontrast nephropathy is an under-recognized event after coronary and radiographic angiography, with major morbidity and mortality. Patients at greatest risk for RCN can be defined prior to the procedure based on age, presence of diabetes, and presence of preexisting renal dysfunction. Despite attempts to alter preprocedural hydration, amount of dye administered, and postprocedural therapies, this clinical event continues to affect over 25% of patients at high risk. This discussion will review the literature in order to understand the attempts that have been made to prevent radiocontrast nephropathy.
Bailey
S R
SR
University of Texas Health Sciences Center at San Antonio, TX, USA.
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000401:mortality / Q000517:prevention & control*; D003287:Contrast Media / Q000009:adverse effects*; D017023:Coronary Angiography / Q000009:adverse effects; D004232:Diuretics / Q000627:therapeutic use*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D011322:Primary Prevention / Q000379:methods / Q000639:trends*; D019275:Radiopharmaceuticals / Q000009:adverse effects*; D016032:Randomized Controlled Trials as Topic; D012079:Renal Circulation / Q000187:drug effects; D018570:Risk Assessment; D015996:Survival Rate; D016896:Treatment Outcome
D003287:Contrast Media; D004232:Diuretics; D018491:Dopamine Agonists; D019275:Radiopharmaceuticals