title: The autolysin of Porphyromonas gingivalis is involved in outer membrane vesicle release.
abstract: An autolysin mutant of Porphyromonas gingivalis was constructed and its outer membrane vesicle production was compared to that of wild-type strain 381. The autolysin mutant produced elevated levels of vesicles relative to the parental strain. It is suggested that vesicle formation of this organism may be regulated by cell wall turnover.
authors.affiliation: Department of Oral Biology, State University of New York, 3435 Main Street, Buffalo, NY 14214, USA.
authors.forename: Jun-ichiro
authors.initials: J
authors.lastname: Hayashi
authors.forename: Nobushiro
authors.initials: N
authors.lastname: Hamada
authors.forename: Howard K
authors.initials: HK
authors.lastname: Kuramitsu
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D002455:Cell Division; D002462:Cell Membrane / Q000201:enzymology; D003470:Culture Media; D008854:Microscopy, Electron; D009238:N-Acetylmuramoyl-L-alanine Amidase / Q000502:physiology*; D016966:Porphyromonas gingivalis / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure; D014617:Vacuoles / Q000502:physiology / Q000648:ultrastructure; D014774:Virulence
chemical_list: D001425:Bacterial Outer Membrane Proteins; D003470:Culture Media; D009238:N-Acetylmuramoyl-L-alanine Amidase