title: Aggressive wear testing of a cross-linked polyethylene in total knee arthroplasty.
abstract: Recently, highly cross-linked polyethylenes with high wear and oxidation resistance have been developed. These materials may improve the in vivo performance of polyethylene components used in total knee arthroplasty. To date, the in vitro knee wear testing of these new polyethylenes has been done under conditions of normal gait. However, their critical assessment also must include aggressive in vitro fatigue and wear testing. In the current study, an aggressive in vitro knee wear and device fatigue model simulating a tight posterior cruciate ligament balance during stair climbing was developed and used to assess the performance of one type of highly cross-linked polyethylene tibial knee insert in comparison with conventional polyethylene. The highly cross-linked inserts and one group of conventional inserts were tested after sterilization. One additional group of conventional inserts was subjected to accelerated aging before testing. The articular surfaces of the inserts were inspected visually for surface delamination, cracking, and pitting at regular intervals during the test. The aged conventional polyethylene inserts showed extensive delamination and cracking as early as 50,000 cycles. In contrast, the unaged conventional and highly cross-linked polyethylene inserts did not show any subsurface cracking or delamination at 0.5 million cycles. The appearance and location of delamination that occurred in the aged conventional inserts tested with the current model previously have been observed in vivo with posterior cruciate-sparing design knee arthroplasties with a tight posterior cruciate ligament.
authors.affiliation: Orthopaedic Biomechanics and Biomaterials Laboratory, Massachusetts General Hospital, Boston, 02114, USA.
authors.forename: Orhun K
authors.initials: OK
authors.lastname: Muratoglu
authors.forename: Charles R
authors.initials: CR
authors.lastname: Bragdon
authors.forename: Daniel O
authors.initials: DO
authors.lastname: O'Connor
authors.forename: Rebecca S
authors.initials: RS
authors.lastname: Perinchief
authors.forename: Murali
authors.initials: M
authors.lastname: Jasty
authors.forename: William H
authors.initials: WH
authors.lastname: Harris
mesh_terms: D007720:Knee Prosthesis; D008422:Materials Testing; D010084:Oxidation-Reduction; D020959:Polyethylene; D011095:Polyethylenes; D011475:Prosthesis Failure; D013314:Stress, Mechanical
chemical_list: D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D020959:Polyethylene