Controlling and monitoring polymyositis under steroid therapy.
This paper illustrates how considerable information may be extracted from the easily obtained serum creatine kinase levels as a function of prednisolone intake in controlling and monitoring polymyositis effectively. A simple process is developed to enable a clinician to determine readily the optimum prednisolone intake to give the minimum average steroid levels within the patient with an effective reduction in the muscle damage arising from the polymyositis. As part of the process it is demonstrated how the effect of other drugs or natural products may be ascertained and monitored. The effects of specific Mannatech products are detailed as an example.
Golding
E M
EM
Department of Anesthesiology, Baylor College of Medicine, Houston, TX 77030, USA. egolding@bcm.tmc.edu
Golding
R M
RM
D003402:Creatine Kinase / Q000097:blood; D019587:Dietary Supplements; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods; D017285:Polymyositis / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D011239:Prednisolone / Q000493:pharmacokinetics / Q000627:therapeutic use*; D012016:Reference Values; D013256:Steroids / Q000493:pharmacokinetics / Q000627:therapeutic use*
D013256:Steroids; D011239:Prednisolone; D003402:Creatine Kinase