title: Effect of megestrol caproate on the reproductive function of laboratory animals.
abstract: In vivo experiments on rats and rabbits showed that megestrol caproate, a 17-alpha-hydroxyprogesterone derivative exhibits 10-fold higher gestagenic activity compared to progesterone and possesses no androgenic, anabolic, and estrogenic activities.
authors.affiliation: Laboratory of Pharmacology, D. O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, St. Petersburg. isscapirz@peterlink.ru
authors.forename: O L
authors.initials: OL
authors.lastname: Pirzada
mesh_terms: D000818:Animals; D003270:Contraceptive Agents / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D008535:Megestrol / Q000031:analogs & derivatives / Q000494:pharmacology*; D045167:Progesterone Congeners / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
chemical_list: D003270:Contraceptive Agents; D045167:Progesterone Congeners; C475055:megestrol caproate; D008535:Megestrol