Immunomodulatory sesquiterpene glycosides from Dendrobium nobile.
Four sesquiterpene glycosides with alloaromadendrane, emmotin, and picrotoxane type aglycones were isolated from the stems of Dendrobium nobile Lindl (Orchidaceae). Their structures were determined by spectroscopic methods and chemical reactions. Immunomodulatory activity of the isolates was evaluated in vitro.
Ye
Qinghua
Q
Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shinghai 200031, People's Republic of China.
Qin
Guowei
G
Zhao
Weimin
W
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D031667:Dendrobium / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000494:pharmacology*; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects*; D051379:Mice; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology
D006027:Glycosides; D012717:Sesquiterpenes