Concentrations and enantiomer fractions of organochlorine compounds in Baltic species hit by reproductive impairment.
Concentrations and enantiomer fractions (EFs) of organochlorine compounds (OCs) were determined in tissues of gray seal (Halichoerus grypus) and salmon (Salmo salar) originating from the Baltic Sea. The selected seal specimens ranged from starved to unstarved animals, and some of them suffered from a disease complex, while the salmon samples originated from individuals, which were known to produce offspring with and without the M74 syndrome. Significant differences in residue levels and EFs were found between seal groups but not between M74 salmon and non-M74 salmon. The relations between chemical and biological variables of seal samples were investigated with multivariate statistics. Poor health status correlated strongly with age, while bad nutrition condition was associated mainly with high pollution loads and distinctively nonracemic chiral OC compositions. High biotransformation rate (as indicated by fraction of chlordane metabolites in relation to total level of chlordanes) was also associated with large deviations from racemic values and high contaminant levels.
Wiberg
Karin
K
Department of Chemistry, Environmental Chemistry, Umeå University, SE-901 87 Umeå, Sweden. karin.wiberg@chem.umu.se
Bergman
Anders
A
Olsson
Mats
M
Roos
Anna
A
Blomkvist
Gun
G
Haglund
Peter
P
D000818:Animals; D001454:Baltic States; D001711:Biotransformation; D005260:Female; D006304:Health Status; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides / Q000009:adverse effects* / Q000378:metabolism / Q000493:pharmacokinetics*; D008297:Male; D012098:Reproduction / Q000187:drug effects; D020317:Salmo salar / Q000502:physiology*; D046048:Seals, Earless / Q000502:physiology*; D014018:Tissue Distribution; D014874:Water Pollutants, Chemical / Q000009:adverse effects* / Q000378:metabolism / Q000493:pharmacokinetics*
D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D014874:Water Pollutants, Chemical