title: Are there naturally occurring pleomorphic bacteria in the blood of healthy humans?
abstract: Dark-field microscopy of blood from healthy individuals revealed the existence of pleomorphic microorganisms. These bacteria exhibited limited growth and susceptibility to antibiotics and could be detected by fluorescent in situ hybridization and flow cytometry. They were further characterized by analysis of their 16S rRNA and gyrB genes.
authors.affiliation: Faculty of Dentistry, McGill University, Montreal, Quebec H3A 2B4, Canada.
authors.forename: Richard W
authors.initials: RW
authors.lastname: McLaughlin
authors.forename: Hojatollah
authors.initials: H
authors.lastname: Vali
authors.forename: Peter C K
authors.initials: PC
authors.lastname: Lau
authors.forename: Roger G E
authors.initials: RG
authors.lastname: Palfree
authors.forename: Angela
authors.initials: A
authors.lastname: De Ciccio
authors.forename: Marc
authors.initials: M
authors.lastname: Sirois
authors.forename: Darakhshan
authors.initials: D
authors.lastname: Ahmad
authors.forename: Richard
authors.initials: R
authors.lastname: Villemur
authors.forename: Marcel
authors.initials: M
authors.lastname: Desrosiers
authors.forename: Eddie C S
authors.initials: EC
authors.lastname: Chan
mesh_terms: D001419:Bacteria / Q000235:genetics / Q000254:growth & development* / Q000302:isolation & purification* / Q000648:ultrastructure; D001769:Blood / Q000382:microbiology*; D027081:DNA Gyrase / Q000235:genetics; D004269:DNA, Bacterial / Q000032:analysis; D004275:DNA, Ribosomal / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008854:Microscopy, Electron; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S; D027081:DNA Gyrase