Low temperature crystal structure of natural diosgenone.
The molecular structure of diosgenone, a natural steroidal sapogenin, closely related to diosgenin and isolated from Solanum nudum, was solved by single crystal X-ray diffractometry at 120 K and refined by full-matrix least-squares to an agreement factor, R1 = 0.054. It crystallizes in the monoclinic space group P2(1), with a = 15.1870(4) A, b = 7.2710(2) A, c = 21.2840(6) A, beta = 99.251(1) degrees, and four molecules in the unit cell (Z = 4). The results constitute the first structural report on a steroidal sapogenin from the diosgenin group.
Piro
Oscar E
OE
Departamento di Física and Instituto IFLP (CONICET), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina.
Castellano
Eduardo E
EE
Tobón Zapata
Gloria E
GE
Blair Trujillo
Silvia
S
Baran
Enrique J
EJ
D018360:Crystallography, X-Ray / Q000379:methods; D005615:Freezing; D008958:Models, Molecular; D008968:Molecular Conformation; D012502:Sapogenins / Q000737:chemistry* / Q000302:isolation & purification; D032322:Solanum / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry* / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification; D014961:X-Ray Diffraction / Q000379:methods
D012502:Sapogenins; D013141:Spiro Compounds; D014315:Triterpenes; C469690:diosgenone