Modifications of eyebrow position with botulinum exotoxin A.
OBJECTIVE
To determine if clinically used botulinum exotoxin A (Botox) injections to the forehead and glabellar and crow's-feet regions result in modifications of eyebrow position.


METHODS
Prospective study.


METHODS
Academic medical center in St Louis, Mo.


METHODS
Twenty-nine adult patients treated with botulinum exotoxin A injections for rhytids.


METHODS
The eyebrow position at 13 different sites was measured before injection and 2 weeks after treatment. The areas injected were based on patient preference and physician assessment. Of the 29 patients, 14 received injections into the glabella only and 15 received injections into the glabella and forehead, with or without treatment of the crow's-feet.


RESULTS
In 29 patients at rest, we found no significant (P value range,.17 to.97) change in eyebrow position, except for a point depression at the right lateral eyebrow. The 15 patients who received injections into the forehead and glabella, with or without treatment of the crow's-feet, had no significant (P value range,.11 to.84) change in eyebrow position, except for a point of depression at the left medial eyebrow. Both groups exhibited eyebrow depression in the active state (eyebrow maximally elevated).


CONCLUSIONS
Botulinum exotoxin A injections into the forehead and glabellar, and crow's-feet regions did not significantly change the resting eyebrow position. However, forehead injections contributed to eyebrow depression in the active state.
Kokoska
Mimi S
MS
Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, 550 N University Blvd, Room 3170, Indianapolis, IN 46202, USA.
Amato
Jason B
JB
Hollenbeak
Christopher S
CS
Glaser
Dee Anna
DA
D000328:Adult; D000368:Aged; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D003357:Cosmetic Techniques; D005138:Eyebrows / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015595:Skin Aging
D019274:Botulinum Toxins, Type A