Retention characteristics and practical applications of carbon sorbents.
Reversed-phase separations provides a versatile technique in high-performance liquid chromatography. Porous graphitized carbon (PGC) support shows unique retention characteristics. Separations on PGC columns use typical reversed-phase eluents (water and organic modifiers miscible with water), however, the retention order of solutes generally does not follow their hydrophobicity order. Molecular hydrophobicity influences but not determines the elution order of any set of solutes. The properties of these supports, mechanisms of retention and application are discussed, along with correlations which can guide the choice of solvent combinations for typical separations.
Forgács
Esther
E
Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, P.O.Box 17. H-1525 Budapest, Hungary.
D000327:Adsorption; D016573:Agrochemicals / Q000032:analysis; D001685:Biological Factors / Q000032:analysis; D002244:Carbon / Q000737:chemistry*; D002845:Chromatography / Q000295:instrumentation*; D004364:Pharmaceutical Preparations / Q000032:analysis; D015262:Xenobiotics / Q000032:analysis
D016573:Agrochemicals; D001685:Biological Factors; D004364:Pharmaceutical Preparations; D015262:Xenobiotics; D002244:Carbon