Immunosuppression in uveitis.
The treatment of ocular inflammatory disease continues to be a major challenge as the clinician tries to balance the risks and the benefits of immunosuppressive therapy. Currently, corticosteroids, antimetabolites, and calcineurin inhibitors are the most commonly used agents. Biologically active agents including monoclonal antibodies, however, provide a promising new form of treatment that can target the immune system more specifically and more safely. Long-term studies are needed to determine the role of biologic agents in the treatment of uveitis.
Djalilian
Ali R
AR
National Eye Institute, National Institutes of Health, 10 Center Drive, Building 10, Room 10N112, Bethesda, MD 20892, USA.
Nussenblatt
Robert B
RB
D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D014605:Uveitis / Q000188:drug therapy*
D007166:Immunosuppressive Agents