No false start for novel pseudotyped vectors.
Pseudotyped vectors can be used to introduce genes into cells or to study the entry process of the virus from which the outer shell of the recombinant virus is derived. Recently, several novel pseudotyped retroviruses and lentiviruses have been constructed. Virus vectors pseudotyped with an alphavirus glycoprotein hold special promise. The increasing diversity of the available pseudotyped vectors offers expanded opportunities for gene transfer to specific cells.
Sanders
David Avram
DA
Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA. retrovir@bragg.bio.purdue.edu
D004274:DNA, Recombinant / Q000235:genetics / Q000627:therapeutic use; D003673:Defective Viruses / Q000235:genetics*; D015967:Gene Expression Regulation, Viral; D018014:Gene Transfer Techniques; D005818:Genetic Engineering / Q000379:methods; D015316:Genetic Therapy / Q000379:methods; D005822:Genetic Vectors / Q000235:genetics* / Q000627:therapeutic use; D016679:Genome, Viral; D016086:Lentivirus / Q000235:genetics; D011995:Recombination, Genetic; D012190:Retroviridae / Q000235:genetics; D014161:Transduction, Genetic / Q000379:methods*; D015678:Viral Structural Proteins / Q000235:genetics; D014780:Viruses / Q000235:genetics
D004274:DNA, Recombinant; D015678:Viral Structural Proteins