Phylogenetic background and virulence profiles of fluoroquinolone-resistant clinical Escherichia coli isolates from the Netherlands.
Thirteen fluoroquinolone-resistant Escherichia coli (FQREC) isolates from hospitalized patients in the Netherlands were found to represent predominantly (low-virulence) phylogenetic groups A and B1 and to lack extraintestinal virulence traits. These FQREC resemble animal-source E. coli and presumably pose little threat to noncompromised hosts. Similar analysis of other FQREC is needed.
Johnson
James R
JR
Medical Service, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA. johns007@umn.edu
van der Schee
Cindy
C
Kuskowski
Michael A
MA
Goessens
Wil
W
van Belkum
Alex
A
D000890:Anti-Infective Agents / Q000494:pharmacology*; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects* / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D024841:Fluoroquinolones; D005838:Genotype; D006761:Hospitals; D006801:Humans; D009426:Netherlands / Q000453:epidemiology; D010802:Phylogeny; D014774:Virulence / Q000235:genetics
D000890:Anti-Infective Agents; D004269:DNA, Bacterial; D024841:Fluoroquinolones