Endothelin receptor antagonists and cerebral vasospasm: an update.
THIS REVIEW UPDATES: the current status of endothelin receptor antagonists in the treatment of cerebral vasospasm. Recent preclinical and clinical studies are reviewed, as well as clinical trials for other medical indications. Some of the newer endothelin receptor antagonists are also examined.
Chow
Michael
M
Department of Neurosurgery, University of Virginia, Charlottesville, Virginia22908-0212, USA.
Dumont
Aaron S
AS
Kassell
Neal F
NF
D000818:Animals; D065128:Endothelin Receptor Antagonists; D016232:Endothelins / Q000378:metabolism; D006801:Humans; D017466:Receptors, Endothelin / Q000378:metabolism; D020301:Vasospasm, Intracranial / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology
D065128:Endothelin Receptor Antagonists; D016232:Endothelins; D017466:Receptors, Endothelin