4'-deoxy iridoid glycosides from Centranthus longiflorus.
The new iridoid glycosides, 4'-deoxykanokoside A and 4'-deoxykanokoside C, were isolated from the methanolic root extract of Centranthus longiflorus ssp. longiflorus. They were accompanied by the three known iridoid glycosides, kanokoside A, kanokoside C and valerosidatum, and two known phenylpropanoid glycosides, coniferin and isoconiferinoside. The structures were elucidated mainly by spectroscopic methods. The presence of 4-deoxy glucose as a part of plant glycosides is rather unusual. Cytotoxic effects of the isolated compounds were also investigated.
Kuruüzüm-Uz
Ayşe
A
Hacettepe University, Faculty of Pharmacy, Department of Pharmacognosy, TR-06100, Ankara, Turkey. ayseuz@hacettepe.edu.tr
Güvenalp
Zuhal
Z
Omür Demirezer
L
L
Bergère
Isabelle
I
Ströch
Karsten
K
Zeeck
Axel
A
D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D028161:Valerianaceae / Q000737:chemistry*
D039823:Iridoids