23Na-MRI of the human heart using a 3D radial projection technique.
Sodium MRI has the potential to differentiate viable and non-viable infarcted myocardium. The accurate quantification of the total sodium content requires imaging techniques with ultra short echo times below 0.5 ms. We present a 3D-radial projection technique which allows the acquisition of ECG-triggered sodium images of the human heart with echo times of 0.4 ms. A 3D-data set of the heart of a volunteer was acquired within less than 18 min on a clinical scanner (1.5 T), achieving a SNR of 10 in the myocardium with an isotropic resolution of 10 mm. This technique provides a tool for clinical studies of ischemic heart diseases.
Jerecic
R
R
Abt. Biophysik u. Med. Strahlenphysik, Deutsches Krebsforschungszentrum Heidelberg, Deutschland. r.jerecic@dkfz-heidelberg.de
Bock
M
M
Wacker
C
C
Bauer
W
W
Schad
L R
LR
D004562:Electrocardiography; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology; D009206:Myocardium / Q000473:pathology; D012680:Sensitivity and Specificity; D012964:Sodium / Q000378:metabolism*; D015222:Sodium Channels / Q000502:physiology*; D013996:Time and Motion Studies; D014022:Tissue Survival / Q000502:physiology
D015222:Sodium Channels; D012964:Sodium