Triterpene and coumarins from Skimmia laureola.
In the course of our studies on the chemical constituents of the leaves of Skimmia laureola, a new triterpene O-methyl cyclolaudenol (1) and a new coumarin, (+)-7-methoxy-6-(2'R-methoxy-3'-hydroxy-3'-methyl butyl) coumarin (2) were isolated. In addition five known coumarins, isogospherol (3), heraclenol (4), 5,8-dimethoxy coumarin-2H-1-benzopyran-2-one (5), 7-methoxy-6[2'-oxo-3'-methyl butyl] coumarin (6), and (+)-ulopterol (7) were also isolated for the first time from this plant. The structures were identified by spectroscopic studies and the stereochemistry at C-2' in compounds 3 and 4 were established by Horeau's procedure.
Atta-Ur-Rahman
H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Pakistan. hej@cyber.net.pk
Sultana
Nighat
N
Khan
M Riaz
MR
Choudhary
M Iqbal
MI
D003374:Coumarins / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D027821:Rutaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*
C470596:7-methoxy-6-(2'-methoxy-3'-hydroxy-3'-methyl butyl); D003374:Coumarins; C470595:O-methyl cyclolaudenol; D014315:Triterpenes