title: Essential oil constituents of Valeriana italica and Valeriana tuberosa. Stereochemical and conformational study of 15-acetoxyvaleranone.
abstract: The chemical composition of the essential oils obtained by hydrodistillation of roots, stems with leaves and inflorescences of Valeriana italica Lam. and Valeriana tuberosa L. were studied by GC/MS. Seventy-three and forty-one constituents were identified from each plant, respectively. The major constituent of the oil obtained from the roots of V. italica was isolated and identified as 15-acetoxyvaleranone. Its stereochemistry and conformation has been studied using NMR spectroscopy and molecular modelling. The oils obtained from V. tuberosa completely lacked the characteristic valerane or kessane sesquiterpenes.
authors.affiliation: Department of Pharmacy, University of Athens, Greece.
authors.forename: Nikolas
authors.initials: N
authors.lastname: Fokialakis
authors.forename: Prokopios
authors.initials: P
authors.lastname: Magiatis
authors.forename: Sofia
authors.initials: S
authors.lastname: Mitaku
mesh_terms: D000085:Acetates / Q000737:chemistry* / Q000302:isolation & purification; D035264:Flowers / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D008968:Molecular Conformation; D009281:Naphthalenes / Q000737:chemistry* / Q000302:isolation & purification; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D013237:Stereoisomerism; D028161:Valerianaceae / Q000737:chemistry*
chemical_list: C469688:15-acetoxyvaleranone; D000085:Acetates; D009281:Naphthalenes; D009822:Oils, Volatile