title: Familial cluster headache: a series of 186 index patients.
abstract: OBJECTIVE
  To investigate the familial occurrence of cluster headache in a series of French patients fulfilling the International Headache Society diagnosis criteria.
  
  
  METHODS
  One hundred eighty-six index patients and 624 first-degree relatives were surveyed.
  
  
  RESULTS
  A positive family history of cluster headache was found in 20 index patients (10.75%) with 22 affected first-degree relatives (3.4%). In multiplex families 6 of the 68 second-degree relatives that were contacted had cluster headache.
  
  
  CONCLUSIONS
  No precise mode of inheritance could be drawn from the observed repartition of cases within multiplex families.
authors.affiliation: Service de Neurologie, Clinique de Courlancy, Reims, France. mohammed.el-amrani@lrb.ap-hop-paris.fr
authors.forename: Mohammed
authors.initials: M
authors.lastname: El Amrani
authors.forename: Anne
authors.initials: A
authors.lastname: Ducros
authors.forename: Pauline
authors.initials: P
authors.lastname: Boulan
authors.forename: Saadia
authors.initials: S
authors.lastname: Aidi
authors.forename: Isabelle
authors.initials: I
authors.lastname: Crassard
authors.forename: Jean Marc
authors.initials: JM
authors.lastname: Visy
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Tournier-Lasserve
authors.forename: Marie Germaine
authors.initials: MG
authors.lastname: Bousser
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003027:Cluster Headache / Q000453:epidemiology* / Q000235:genetics*; D005192:Family Health; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D017678:Sex Distribution