title: Macular hole following photodynamic therapy.
abstract: A 66-year-old woman with prior posterior vitreous detachment underwent photodynamic therapy with verteporfin for a juxtafoveolar choroidal neovascularization. Twenty days after the photodynamic therapy, fluorescein angiography showed regression of the membrane and the new onset of a macular hole. Macular hole formation following photodynamic therapy could be related to choroidal swelling leading to dehiscence of the foveal pit, or to exacerbation of either tangential traction or cystoid spaces by the laser administered over the fovea.
authors.affiliation: Department of Ophthalmology, American University of Beirut, Beirut, Lebanon.
authors.forename: Ahmad M
authors.initials: AM
authors.lastname: Mansour
authors.forename: Ziad M
authors.initials: ZM
authors.lastname: Husseini
authors.forename: Alex R
authors.initials: AR
authors.lastname: Schakal
mesh_terms: D000368:Aged; D020256:Choroidal Neovascularization / Q000188:drug therapy; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000008:administration & dosage; D011166:Porphyrins / Q000008:administration & dosage; D012167:Retinal Perforations / Q000209:etiology*; D016896:Treatment Outcome; D000077362:Verteporfin; D014792:Visual Acuity
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin