Proneural, prosensory, antiglial: the many faces of neurogenins.
Previous reports have linked Neurogenin 1 with the general promotion of neurogenesis and gliogenesis. A new study in zebrafish, supported by recent findings in Drosophila, has now challenged this idea by demonstrating that the activity of Neurogenin 1 is limited to activation of development of two classes of sensory neurons.
Korzh
Vladimir
V
Institute of Molecular and Cell Biology, 1 Research Link, National University of Singapore, Singapore 117604. vlad@imcb.nus.edu.sg
Strähle
Uwe
U
D000818:Animals; D051792:Basic Helix-Loop-Helix Proteins; D005075:Biological Evolution; D002454:Cell Differentiation / Q000235:genetics*; D009419:Nerve Tissue Proteins / Q000502:physiology*; D009457:Neuroglia / Q000502:physiology; D009475:Neurons, Afferent / Q000502:physiology*; D029867:Xenopus Proteins
D051792:Basic Helix-Loop-Helix Proteins; D009419:Nerve Tissue Proteins; D029867:Xenopus Proteins; C101907:neurogenin, Xenopus