title: Peripheral Primitive Neuroectodermal Tumor (Peripheral Neuroepithelioma) in a Dog.
abstract: A peripherally located primitive neuroectodermal tumor (peripheral PNET) originating in subcutaneous tissues was observed in an adult Beagle. The highly aggressive tumor spread rapidly and metastasized to various organs. The neoplasm was diagnosed as a peripheral PNET on the basis of morphologic and immunohistochemical characteristics such as small round tumor cells, rosette formations, many interdigitating cytoplasmic processes, neurosecretory granules and microtubules, and positive immunohistochemical reactions to neurogenic markers. We describe here the first report of a peripheral PNET in a dog. Peripheral PNET should be included in the list of differential diagnoses for soft-tissue tumors in dogs.
authors.affiliation: Drug Safety Research Laboratories, Eisai Co., Ltd.; Takehaya, Kawashima-cho, Hashima-gun, Gifu 501-61, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Hosokawa
authors.forename: Shiro
authors.initials: S
authors.lastname: Suzuki
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Hibino
authors.forename: Taneo
authors.initials: T
authors.lastname: Fukuta
authors.forename: Toshio
authors.initials: T
authors.lastname: Imai
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Hayakawa
authors.forename: Junichi
authors.initials: J
authors.lastname: Nakanowatari
authors.forename: Fumio
authors.initials: F
authors.lastname: Sagami