Clostridial enteritis necroticans versus secondary clostridial infection superimposed upon ischemic bowel disease.
Clostridial enteritis necroticans, or pig-bel, as seen in Papua New Guinea, is a necrotizing, segmental gangrene of the small intestine occurring in members of a malnourished population, who become ill after consuming large quantities of pork contaminated with Type C. Clostridium perfringens. We report a case of possible Clostridial enteritis necroticans with concomitant ischemic intestinal disease secondary to superior mesenteric arterial thrombosis occurring in a 53-year-old woman with a long history of diabetes mellitus, hypertension, and peripheral vascular disease. The differential diagnosis and the pathogenesis of C. perfringens enteritis necroticans are discussed.
Zhao
Weiqiang
W
Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Daroca
Philip J
PJ
Crawford
Byron E
BE
D000328:Adult; D003015:Clostridium Infections / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology; D003016:Clostridium perfringens / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D020345:Enterocolitis, Necrotizing / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007422:Intestines / Q000098:blood supply; D007511:Ischemia / Q000150:complications; D008145:Louisiana