title: Holding it together: chromatin in the Archaea.
abstract: Recently, several advances have been made in the understanding of the form and function of archaeal chromatin. Remarkable parallels can be drawn between the structure and modification of chromatin components in the archaeal and the eukaryotic domains of life. Indeed, it now appears that key components of the hugely complex eukaryotic chromatin regulatory machinery were established before the divergence of the archaeal and eukaryotic lineages.
authors.affiliation: Centre for Biomolecular Sciences, St Andrews University, North Haugh, St Andrews, KY16 9ST, Fife, UK.
authors.forename: Malcolm F
authors.initials: MF
authors.lastname: White
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Bell
mesh_terms: D000595:Amino Acid Sequence; D019843:Archaeal Proteins / Q000235:genetics / Q000502:physiology; D002843:Chromatin / Q000737:chemistry* / Q000235:genetics* / Q000502:physiology; D004247:DNA / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology; D005057:Eukaryotic Cells / Q000737:chemistry / Q000502:physiology; D006657:Histones / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D008969:Molecular Sequence Data; D016944:Sulfolobus / Q000737:chemistry* / Q000235:genetics* / Q000502:physiology
chemical_list: D019843:Archaeal Proteins; D002843:Chromatin; D004268:DNA-Binding Proteins; D006657:Histones; C444360:Sso10b protein, Sulfolobus solfataricus; D004247:DNA