title: [Recurrent hemoptysis as initial symptom of a thoracic angiomatosis in an adult patient].
abstract: METHODS
  A 24-year-old man presented with recurrent hemoptysis and decreased exercise capacity. DIAGNOSTIC FINDINGS: The chest radiograph demonstrated multiple disseminated pulmonary nodules. In addition the patient developed a hematopericardium with tamponade. The further diagnostic approach revealed an extensive thoracic angiomatosis affecting the lung and the heart.
  
  
  METHODS
  Tumor resection could not be performed. A therapy with Interferon alpha-2a was initiated. After 3 month a significant regression of the pulmonary angiomatosis was documented. On the other hand the cardiac tumor showed no therapeutic response.
  
  
  CONCLUSIONS
  Thoracic angiomatosis should be considered in the differential diagnosis of otherwise unclear hemoptysis or hematopericardium. Diagnosis intra vitamin requires an aggressive and invasive approach. Interferon alpha-2a is effective in palliative treatment of diffuse angiomatous diseases. But not all angiomatous processes respond to that therapy.
authors.affiliation: Klinikum Ingolstadt, Medizinische Klinik I, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Bastian
authors.forename: B
authors.initials: B
authors.lastname: Mödl
authors.forename: K
authors.initials: K
authors.lastname: Nentwich
authors.forename: G
authors.initials: G
authors.lastname: Engel
authors.forename: E
authors.initials: E
authors.lastname: Brunner
authors.forename: K
authors.initials: K
authors.lastname: Holper
mesh_terms: D000328:Adult; D000798:Angiomatosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D003937:Diagnosis, Differential; D006469:Hemoptysis / Q000209:etiology*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D008171:Lung Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D011859:Radiography; D011994:Recombinant Proteins; D012008:Recurrence
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins