title: Fluoride release from newly developed dental adhesives.
abstract: This study compared fluoride release from three fluoride-releasing dental adhesives (Trial KBF Bond, One-up Bond F, Reactmer Bond) and one conventional dental adhesive (Clearfil SE Bond) for 70 days in vitro. From each material, five disk-shaped specimens (diameter: 9.0 mm, height: 1.5 mm) were prepared and immersed in 5 ml of 10 mM phosphate buffered solution (pH 7.0). After 1, 3, 7, 14, 21, 28, 35, 42, 49, 56, 63 and 70 days, the samples were transferred into new solutions. The fluoride content was determined with a combined fluoride sensitive electrode attached to an ion analyzer. Data were statistically analyzed with ANOVA, followed by Scheffé's test. Reactmer Bond showed the greatest fluoride release over 70 days (280.2 +/- 10.1 micrograms/cm2) among the materials tested. The values for One-up Bond F and Trial KBF Bond were 83.4 +/- 5.3 micrograms/cm2 and 58.6 +/- 1.5 micrograms/cm2, respectively. The values were significantly different among the four groups (p < 0.0001). Clearfil SE Bond showed almost no fluoride release over 70 days.
authors.affiliation: Third Department of Conservative Dentistry, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kameyama
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Tsumori
authors.forename: Takeo
authors.initials: T
authors.lastname: Ushiki
authors.forename: Yoshitake
authors.initials: Y
authors.lastname: Muto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Koga
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsukubo
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Hirai
mesh_terms: D000704:Analysis of Variance; D002327:Cariostatic Agents / Q000737:chemistry*; D001840:Dental Bonding; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D005459:Fluorides / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry*; D017736:Ion-Selective Electrodes; D008689:Methacrylates / Q000737:chemistry; D019279:Resin Cements / Q000737:chemistry*; D018709:Statistics, Nonparametric; D013997:Time Factors
chemical_list: D002327:Cariostatic Agents; C438313:Clearfil SE Bond; D017220:Dentin-Bonding Agents; D005899:Glass Ionomer Cements; C471994:KBF Bond; D008689:Methacrylates; C446260:One-Up-Bond F; D019279:Resin Cements; C447779:reactmer bond; D005459:Fluorides