title: Processing of temporal duration information in working memory after frontodorsal tumour excisions.
abstract: This study aimed to test the hypothesis that impairments of temporal duration processing after frontal lobe lesions reflect deficits in executive monitoring functions rather than a domain-specific deficit in the maintenance of duration information in working memory. Patients with frontodorsal lesions, clinical controls with post-central lesions, and healthy controls performed recognition and classification tasks, which should allow for testing maintenance and monitoring functions, respectively. Results showed mild non-selective impairments of the frontal patients on both temporal and spatial recognition tasks, but a marked selective degradation on temporal classification while performance on spatial classification was unimpaired. This suggests that maintenance of duration information in working memory after frontal lesions is basically preserved but that, depending on executive task characteristics, there is a specific deficit in the strategic organization of this type of information.
authors.affiliation: Max-Planck-Institute of Cognitive Neuroscience, Leipzig, Germany.
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Hälbig
authors.forename: D
authors.initials: D
authors.lastname: Yves von Cramon
authors.forename: Urs D
authors.initials: UD
authors.lastname: Schmid
authors.forename: Claudius
authors.initials: C
authors.lastname: Gall
authors.forename: Angela D
authors.initials: AD
authors.lastname: Friederici
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D005625:Frontal Lobe / Q000473:pathology* / Q000601:surgery*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis*; D008875:Middle Aged; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000175:diagnosis / Q000209:etiology*; D011183:Postoperative Complications; D021641:Recognition, Psychology; D013028:Space Perception / Q000502:physiology; D013998:Time Perception / Q000502:physiology*