title: Steroid and antibacterial steroidal glycosides from marine green alga Codium iyengarii Borgesen.
abstract: The ethyl acetate soluble part of methanolic extract of marine green alga Codium iyengarii collected from Karachi coast of Arabian Sea afforded a new steroid ([structure: see text], iyengadione) and two new steroidal glycosides [iyengaroside-A ([structure: see text]) and B ([structure: see text])] along with clerosterol galactoside ([structure: see text]). Their structures were elucidated with the aid of 1D-NMR spectroscopy and reconfirmed through HMBC experiments. The bactericidal activity of [structure: see text] was also explored and found positive response from iyengaroside-A ([structure: see text]) and clerosterol galactoside ([structure: see text]).
authors.affiliation: HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. hej@digicom.net.pk
authors.forename: Muhammad Shaiq
authors.initials: MS
authors.lastname: Ali
authors.forename: Muhammad
authors.initials: M
authors.lastname: Saleem
authors.forename: Raghav
authors.initials: R
authors.lastname: Yamdagni
authors.forename: Muhammad Ashfaq
authors.initials: MA
authors.lastname: Ali
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D000460:Chlorophyta / Q000737:chemistry*; D004121:Dimethyl Sulfoxide; D005697:Galactosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010154:Pakistan; D013237:Stereoisomerism; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D005697:Galactosides; D006027:Glycosides; D013256:Steroids; C472632:clerosterol galactoside; C472629:iyengadione; C472630:iyengaroside A; C472631:iyengaroside B; D004121:Dimethyl Sulfoxide