Optimal immunosuppression in teenagers.
Adolescence is a difficult time for transplant recipients, who need to cope with the challenges of becoming independent from their parents, as well as taking responsibility for their own behavior and medication. They need to balance their developing sexuality with a body image which may be affected by the side-effects of immunosuppression. It is now anticipated that more than 80% of children will survive their transplant to become teenagers and adults, and it is therefore important to ensure that immunosuppressive medication is acceptable, convenient for drug level monitoring and free of significant long-term side-effects.
Kelly
Deirdre A
DA
The Liver Unit, Birmingham Children's Hospital NHS Trust, Birmingham, UK. Deidre.Kelly@bhamchildren.wmids.nhs.uk
D000293:Adolescent; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D016377:Organ Transplantation; D000297:Psychology, Adolescent; D016559:Tacrolimus / Q000627:therapeutic use
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D009173:Mycophenolic Acid; D016559:Tacrolimus