title: What is paradoxical about Levinthal paradox?
abstract: We would be tempted to state that there has never been a Levinthal paradox. Indeed, Levinthal raised an interesting problem about protein folding, as he realized that proteins have no time to explore exhaustively their conformational space on the way to their native structure. He did not seem to find this paradoxical and immediately proposed a straightforward solution, which has essentially never been refuted. In other words, Levinthal solved his own paradox.
authors.affiliation: Ingénierie Biomoléculaire, Université Libre de Bruxelles, CP 165/64, 50 Avenue Roosevelt, Belgium. mrooman@ulb.ac.be
authors.forename: Marianne
authors.initials: M
authors.lastname: Rooman
authors.forename: Yves
authors.initials: Y
authors.lastname: Dehouck
authors.forename: Jean Marc
authors.initials: JM
authors.lastname: Kwasigroch
authors.forename: Christophe
authors.initials: C
authors.lastname: Biot
authors.forename: Dimitri
authors.initials: D
authors.lastname: Gilis
mesh_terms: D000595:Amino Acid Sequence; D019143:Evolution, Molecular; D007700:Kinetics; D008956:Models, Chemical; D011489:Protein Denaturation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D011506:Proteins