Pure red cell aplasia associated with thymoma.
A case of thymoma with mixed spindle and lymphocytic variety along with acquired, secondary, chronic pure red cell aplasia is an uncommon entity. The presented case is a case of anterior mediastinal tumour with marked anemia. On histopathologic and hematological examinations, it proved to be a case of thymoma along with pure red cell aplasia. High index of suspicion, bone marrow examination, radiological including CT scan examination, total thymectomy after preparation with repeated blood transfusion remains the mainstay of treatment. Prolonged corticosteroid therapy leads to remission for upto ten months after operative intervention.
Lahiri
T K
TK
Department of Cardiovascular and Thoracic Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP, India. tkl@banaras.ernet.in
Agrawal
D
D
Agrawal
Kapil
K
Shukla
Jyoti
J
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012010:Red-Cell Aplasia, Pure / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D013934:Thymectomy / Q000379:methods; D013945:Thymoma / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D013953:Thymus Neoplasms / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones