title: Pine resin and Biopin ointment: effects on cell composition and histochemical changes in wounds.
abstract: We studied the effects of Biopin ointment containing pine resin and used for the therapy of burns, wounds, and purulent and inflammatory diseases on the cell composition of wounds and histochemical changes in the granulation tissue during the therapy of extensive third-degree burns. The preparation stimulated the nonspecific immune response, normalized hemodynamics in damaged regions, and stimulated cell proliferation in the squamous epithelium.
authors.affiliation: Institute of High-Purity Biological Preparations, St. Petersburg. elena@tech.spb.ru
authors.forename: O K
authors.initials: OK
authors.lastname: Khmel'nitskii
authors.forename: A S
authors.initials: AS
authors.lastname: Simbirtsev
authors.forename: V G
authors.initials: VG
authors.lastname: Konusova
authors.forename: G Sh
authors.initials: GSh
authors.lastname: McHedlidze
authors.forename: E Z
authors.initials: EZ
authors.lastname: Fidarov
authors.forename: B A
authors.initials: BA
authors.lastname: Paramonov
authors.forename: V Yu
authors.initials: VY
authors.lastname: Chebotarev
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001453:Balsams / Q000627:therapeutic use; D002056:Burns / Q000188:drug therapy / Q000473:pathology*; D002455:Cell Division / Q000187:drug effects; D004847:Epithelial Cells / Q000187:drug effects; D006097:Granulation Tissue / Q000187:drug effects / Q000473:pathology*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007107:Immune System / Q000187:drug effects; D009824:Ointments; D009930:Organic Chemicals; D012116:Resins, Plant / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001453:Balsams; D009824:Ointments; D009930:Organic Chemicals; D012116:Resins, Plant; C088307:levosin