title: Squamous cell carcinoma arising in a dentigerous cyst in a 16-month-old girl.
abstract: Squamous cell carcinoma arising in a dentigerous cyst is a rare lesion with distinct histopathology and stringent criteria for diagnosis.(1,2) During the past century, <60 cases have been reported.(3) Of the previously documented cases, all have occurred in adults. We present the case of a squamous cell carcinoma arising in a dentigerous cyst in a 16-month-old girl. This case poses interesting questions regarding the pathophysiology of these tumors and highlights the importance of maintaining a high index of suspicion regardless of age when evaluating cystic lesions of the mandible and maxilla.
authors.affiliation: Good Samaritan Region Medical Center, Phoenix Children's Hospital, AZ 85006, USA. scottgulbranson@hotmail.com
authors.forename: Scott H
authors.initials: SH
authors.lastname: Gulbranson
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Wolfrey
authors.forename: John M
authors.initials: JM
authors.lastname: Raines
authors.forename: Brian P
authors.initials: BP
authors.lastname: McNally
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D003803:Dentigerous Cyst / Q000150:complications* / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D011859:Radiography