title: Reconstruction of the sellar floor using Bioglue following transsphenoidal procedures.
abstract: OBJECTIVE
  Cerebrospinal fluid rhinorrhea, pneumocephalus and meningitis are serious complications following transsphenoidal excision of sellar, suprasellar and parasellar lesions. This study evaluates the use of a new bioadhesive, Bioglue as an adjunct in reconstructing the sellar floor and preventing CSF fistula and investigates the possible complications associated with its use.
  
  
  METHODS
  In thirty-two patients (31 pituitary adenomas and 1 meningioma) Bioglue was used to help reconstruct the sellar floor after endonasal transsphenoidal procedures between January 2001 and April 2002 at the Royal Melbourne Hospital.
  
  
  RESULTS
  There were no post-operative CSF rhinorrhea, allergic rhinitis, meningitis, pneumocranium, granulomas or other complications associated with the use of Bioglue.
  
  
  CONCLUSIONS
  This technique of reconstruction of sellar floor using Bioglue is simple and time efficient in preventing CSF fistula formation following transsphenoidal procedures for sellar region lesions.
authors.affiliation: Department of Neurosurgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Vic., Australia.
authors.forename: Arun
authors.initials: A
authors.lastname: Kumar
authors.forename: Nicholas F
authors.initials: NF
authors.lastname: Maartens
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Kaye
mesh_terms: D000236:Adenoma / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002559:Cerebrospinal Fluid Rhinorrhea / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000601:surgery; D008579:Meningioma / Q000601:surgery; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery; D011182:Postoperative Care; D011446:Prospective Studies; D012658:Sella Turcica / Q000601:surgery*; D013101:Sphenoid Sinus / Q000601:surgery; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D014014:Tissue Adhesives