[Effect of antianginal therapy on lipid peroxidation in patients with ischemic heart disease].
Measurement of the blood lipid peroxidation products (lipid hydroperoxides, dienic ketones, and malonic dialdehyde) was carried out in 26 patients with stable angina of effort and in 31 patient with postinfarction cardiosclerosis with due regard for the ejection fraction (intact, reduced) before treatments administration and after institution of antianginal therapy (nitrates, beta-adrenoblockers, nifedipine). The antianginal therapy has been shown to have but insignificant effect on both blood plasma contents of dienic ketones and plasma/erythrocyte content of malonic dialdehyde, which fact is regarded as an indication for use of antioxidant agents.
Selivonenko
V G
VG
Boev
S S
SS
Torbin
E S
ES
D000328:Adult; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008054:Lipid Peroxides / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000378:metabolism*; D009543:Nifedipine / Q000627:therapeutic use; D009566:Nitrates / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use*
D008054:Lipid Peroxides; D009566:Nitrates; D014665:Vasodilator Agents; D011433:Propranolol; D009543:Nifedipine