title: The protein encoded at the 3' end of the serine protease gene of Aeromonas sobria functions as a chaperone in the production of the protease.
abstract: For the successful production of Aeromonas sobria serine protease (ASP), open reading frame 2 (ORF2) protein, encoded at the 3' end of the protease operon, is required. In this study, we examined the action of ORF2 protein. The results showed that the protein associated with ASP in the periplasm and helped ASP to form an active structure.
authors.affiliation: Department of Biochemistry, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro, Japan. nomu@ph.bunri-u.ac.jp
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Nomura
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Fujii
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Yamanaka
authors.forename: Hidetomo
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Keinosuke
authors.initials: K
authors.lastname: Okamoto
mesh_terms: D000333:Aeromonas / Q000201:enzymology*; D001426:Bacterial Proteins / Q000502:physiology*; D018832:Molecular Chaperones / Q000502:physiology*; D009876:Operon; D012697:Serine Endopeptidases / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D018832:Molecular Chaperones; D012697:Serine Endopeptidases