title: Detection of coronary artery stenoses with multislice helical CT angiography.
abstract: OBJECTIVE
  The authors compared multislice CT angiography and selective angiography for the assessment of coronary artery disease.
  
  
  METHODS
  In 28 patients, the presence and degree of coronary artery stenoses were determined in coronary segments prepared with beta-blocker for good image quality with multislice CT.
  
  
  RESULTS
  In 187 coronary artery segments, sensitivity, specificity, and negative predictive value for the detection of stenoses >50% with multislice CT angiography were 81%, 90%, and 97%, respectively. The agreement for determining the degree of stenoses with multislice CT angiography and selective coronary angiography was only moderate (kappa = 0.58).
  
  
  CONCLUSIONS
  Because of the limited spatial resolution, it is not possible with multislice CT angiography to determine the degree the coronary artery stenoses precisely. However, the high negative predictive value indicates that multislice CT may be a suitable tool to reliably rule out coronary artery disease.
authors.affiliation: Department of Clinical Radiology, University of Munich, Klinikum Grosshadern, Marchioninistr. 15, 81377 Munich, Germany. christoph.becker@ikra.med.uni-muenchen.de
authors.forename: Christoph R
authors.initials: CR
authors.lastname: Becker
authors.forename: Andreas
authors.initials: A
authors.lastname: Knez
authors.forename: Alexander
authors.initials: A
authors.lastname: Leber
authors.forename: Hendrik
authors.initials: H
authors.lastname: Treede
authors.forename: B
authors.initials: B
authors.lastname: Ohnesorge
authors.forename: U Joseph
authors.initials: UJ
authors.lastname: Schoepf
authors.forename: Maximilian F
authors.initials: MF
authors.lastname: Reiser
mesh_terms: D000368:Aged; D000792:Angiography / Q000379:methods; D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods