title: A neuronal modeling paradigm in the presence of refractoriness.
abstract: A mathematical characterization of the membrane potential as an instantaneous return process in the presence of refractoriness is investigated for diffusion models of single neuron's activity, assuming that the firing threshold acts as an elastic barrier. Steady-state probability densities and asymptotic moments of the neuronal membrane potential are explicitly obtained in a form that is suitable for quantitative evaluations. For the Ornstein-Uhlenbeck (OU) and Feller neuronal models, closed form expression are obtained for asymptotic mean and variance of the neuronal membrane potential and an analysis of the different features exhibited by the above mentioned models is performed.
authors.affiliation: Dipartimento di Matematica e Applicazioni, Università di Napoli Federico II, Via Cintia, Naples 80126, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Buonocore
authors.forename: V
authors.initials: V
authors.lastname: Giorno
authors.forename: A G
authors.initials: AG
authors.lastname: Nobile
authors.forename: L M
authors.initials: LM
authors.lastname: Ricciardi
mesh_terms: D008959:Models, Neurological; D012032:Refractory Period, Electrophysiological / Q000502:physiology*