title: Plasmodium falciparum serine repeat protein, a new target of monocyte-dependent antibody-mediated parasite killing.
abstract: Using monoclonal antibodies and human affinity-purified antibodies specific to the Plasmodium falciparum 126-kDa serine-rich protein, SERP, we found that these antibodies have no direct effect upon merozoite invasion at the concentrations tested but can cooperate with blood monocytes to strongly inhibit P. falciparum in vitro growth.
authors.affiliation: BioMedical Parasitology Unit, Pasteur Institute, 75015 Paris, France.
authors.forename: Soe
authors.initials: S
authors.lastname: Soe
authors.forename: Subhash
authors.initials: S
authors.lastname: Singh
authors.forename: Daniel
authors.initials: D
authors.lastname: Camus
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Horii
authors.forename: Pierre
authors.initials: P
authors.lastname: Druilhe
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000913:Antibodies, Protozoan / Q000276:immunology*; D000920:Antibody-Dependent Cell Cytotoxicity; D000953:Antigens, Protozoan / Q000276:immunology*; D006801:Humans; D051379:Mice; D009000:Monocytes / Q000276:immunology*; D010963:Plasmodium falciparum / Q000254:growth & development*
chemical_list: D000911:Antibodies, Monoclonal; D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; C057495:serine repeat antigen, Plasmodium