title: [Contribution of ovarian and uterine color Doppler in medically assisted reproduction techniques (ART)].
abstract: Along the menstrual cycle and during pregnancy, small blood vessels proliferate within the uterus and the ovulating ovary. Angiogenic factors such as VEGF are involved in this phenomenon. In the ovulating ovary, neo-angiogenesis spreads progressively inside the dominant follicle wall and plays a role in the maintenance of the corpus luteum, under the influence of LH (or HCG during pregnancy). In ART, the measure of the blood flow is interesting since it correlates to the number and quality of harvested oocytes. Follicle hypoxia may impair chromosomal organization and separation within the oocyte. This neo-angiogenesis is also important in endometrium, in particular for embryo implantation. Ultrasounds with Doppler allow to estimate the endometrial receptivity, especially in IVF cycles. It is assumed that chance for ongoing pregnancy is almost zero if: endometrial thickness is < 8 mm; uterine pulsatility index (PI) is > 3. Doppler ultrasounds are a useful and even mandatory complement to standard vaginal ultrasonoghraphy in ART. It can be viewed as an indicator of the endometrial and follicular "well-being".
authors.affiliation: Inserm, 5, place Arsonval, 69003 Lyon, France. yardaens@santnet.com
authors.forename: Y
authors.initials: Y
authors.lastname: Ardaens
authors.forename: A
authors.initials: A
authors.lastname: Gougeon
authors.forename: C
authors.initials: C
authors.lastname: Lefebvre
authors.forename: P
authors.initials: P
authors.lastname: Thomas
authors.forename: M
authors.initials: M
authors.lastname: Leroy
authors.forename: J L
authors.initials: JL
authors.lastname: Leroy
authors.forename: D
authors.initials: D
authors.lastname: Dewailly
mesh_terms: D004717:Endometrium / Q000098:blood supply / Q000000981:diagnostic imaging; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D018919:Neovascularization, Physiologic; D006080:Ovarian Follicle / Q000502:physiology; D010053:Ovary / Q000098:blood supply* / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011673:Pulsatile Flow; D027724:Reproductive Techniques, Assisted; D018615:Ultrasonography, Doppler, Color; D014599:Uterus / Q000098:blood supply* / Q000000981:diagnostic imaging*