Friedel-Crafts type reaction of ferrocene with beta-ketoesters.
The reaction of ferrocene with beta-ketoesters in the presence of BF3.Et2O or CF3SO3H affords beta-ferrocenyl-alpha,beta-unsaturated esters in 56-83% yield. In the case of alpha-unsubstituted-beta-ketoesters the reaction is totally E-stereoselective.
Plazuk
Damian
D
Department of Organic Chemistry, University of Lodz, 90-136 Lodz, Narutowicza 68, Poland. janzak@krysia.uni.lodz.pl
Zakrzewski
Janusz
J