Prefrontal delay-period activity is affected by visual cues presented outside the memory field.
To examine interactions between primate prefrontal neurons having memory fields, we examined whether primate prefrontal delay-period activity produced by a visual cue presented inside the neuron's memory field is affected by an additional visual cue presented inside or outside the memory field in 39 prefrontal neurons. Delay-period activity was either diminished (43%) or enhanced (16%) when an additional cue was presented at a certain area in the visual field. Since functional interactions among neighboring prefrontal neurons were present, these modulation could be caused by the interactions between neurons having memory fields in different positions.
Inoue
Masato
M
Department of Cognitive Sciences, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan. minoue@pri.kyoto-u.ac.jp
Funahashi
Shintaro
S
D000818:Animals; D003463:Cues; D004594:Electrophysiology; D008253:Macaca mulatta; D008568:Memory / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D017397:Prefrontal Cortex / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*