title: Functional implications on the mechanism of the function of photosystem II including water oxidation based on the structure of photosystem II.
abstract: The structure of photosystem I at 3.8 A resolution illustrated the main structural elements of the water-oxidizing photosystem II complex, including the constituents of the electron transport chain. The location of the Mn cluster within the complex has been identified for the first time to our knowledge. At this resolution, no individual atoms are visible, however, the electron density of the Mn cluster can be used to discuss both the present models of the Mn cluster as revealed from various spectroscopic methods and the implications for the mechanisms of water oxidation. Twenty-six chlorophylls from the antenna system of photosystem II have been identified. They are arranged in two layers, one close to the stromal side and one close to the lumenal side. Comparing the structure of the antenna system of photosystem II with the chlorophyll arrangement in photosystem I, which was recently determined at 2.5 A resolution shows that photosystem II lacks the central domain of the photosystem I antenna, which is discussed in respect of the repair cycle of photosystem II due to photoinhibition.
authors.affiliation: Max-Volmer-Laboratorium für Biophysikalische Chemie und Biochemie, Technische Universität Berlin, Strasse den 17 Juni 135, 10623 Berlin, Germany. pfromme@asu.edu
authors.forename: Petra
authors.initials: P
authors.lastname: Fromme
authors.forename: Jan
authors.initials: J
authors.lastname: Kern
authors.forename: Bernhard
authors.initials: B
authors.lastname: Loll
authors.forename: Jaceck
authors.initials: J
authors.lastname: Biesiadka
authors.forename: Wolfram
authors.initials: W
authors.lastname: Saenger
authors.forename: Horst T
authors.initials: HT
authors.lastname: Witt
authors.forename: Norbert
authors.initials: N
authors.lastname: Krauss
authors.forename: Athina
authors.initials: A
authors.lastname: Zouni
mesh_terms: D018360:Crystallography, X-Ray; D000458:Cyanobacteria / Q000737:chemistry / Q000378:metabolism*; D004579:Electron Transport; D008958:Models, Molecular; D010084:Oxidation-Reduction; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry* / Q000378:metabolism*; D011487:Protein Conformation; D014867:Water / Q000378:metabolism*
chemical_list: D045322:Photosynthetic Reaction Center Complex Proteins; D014867:Water