title: Determination of water-soluble UV-filters in sunscreen sprays by liquid chromatography.
abstract: Liquid chromatography was used for the determination of the three most used water-soluble UV filters, benzophenone-4 (BZ4), terephthalylidene dicamphor sulfonic acid (TDS), and phenylbenzimidazole sulphonic acid (PBS), in aqueous sunscreen sprays. A C18 stationary phase and an isocratic mobile phase of EtOH-20 mM sodium acetate buffer of pH 4.6 (30:70, v/v) were used at a flow-rate of 0.5 ml min(-1). Mobile phase was also used as solvent for samples and standards. UV detection was at 313 nm. The analytical run took 5.5 min. The limits of detection were 0.5, 0.9 and 2 microg ml(-1) for BZ4, TDS and PBS, respectively. The proposed method does not involve highly toxicsolvents.
authors.forename: Alberto
authors.initials: A
authors.lastname: Chisvert
authors.forename: Amparo
authors.initials: A
authors.lastname: Salvador
mesh_terms: D002853:Chromatography, Liquid; D012015:Reference Standards; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet; D013473:Sunscreening Agents / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D013473:Sunscreening Agents