title: A prospective, multicenter study of laboratory cross-contamination of Mycobacterium tuberculosis cultures.
abstract: A prospective study of false-positive cultures of Mycobacterium tuberculosis that resulted from laboratory cross-contamination was conducted at three laboratories in California. Laboratory cross-contamination accounted for 2% of the positive cultures. Cross-contamination should be a concern when an isolate matches the genotype of another sample processed during the same period.
authors.affiliation: San francisco General Hospital Medical Center and University of California, San Francisco, California 94110, USA. rjasmer@itsa.ucsf.edu
authors.forename: Robert M
authors.initials: RM
authors.lastname: Jasmer
authors.forename: Marguerite
authors.initials: M
authors.lastname: Roemer
authors.forename: John
authors.initials: J
authors.lastname: Hamilton
authors.forename: John
authors.initials: J
authors.lastname: Bunter
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Braden
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Shinnick
authors.forename: Edward P
authors.initials: EP
authors.lastname: Desmond
mesh_terms: D015373:Bacterial Typing Techniques / Q000592:standards; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics; D003951:Diagnostic Errors / Q000517:prevention & control; D004866:Equipment Contamination / Q000517:prevention & control; D005189:False Positive Reactions; D006801:Humans; D007753:Laboratories / Q000592:standards*; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000254:growth & development / Q000302:isolation & purification*; D012150:Polymorphism, Restriction Fragment Length; D013048:Specimen Handling; D014376:Tuberculosis / Q000175:diagnosis* / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial