title: [Contractile reserve as a new parameter for determining the performance of the heart muscle using a noninvasive measuring method].
abstract: Chronic cardiac insufficiency is an illness with increasing epidemiological importance and mortality. Therefore different invasive and non-invasive investigation methods for early recording were developed. The left ventricular ejection fraction (LVEF) has played a special role in this direction. The determination of the contractile reserve by means of non-invasive measurement of blood pressure and flow through the aortic valve is a new and up to now widely unknown method for recording the capability and power reserve of the of myocardium. Since no comparative investigations are known from literature and results from a follow-up are not available yet, we tested whether, by means of contractile reserve, the discrimination of subjects with different cardiac power is possible or not. Forty-two men between 44 and 62 years of age belonging to three groups with different cardiac power (persistence trained, healthy subjects and patients with CHD) were examined non-invasively. The main result of the study is that it is possible to distinguish between the three groups significantly by means of the contractile reserve. The largest value (15.25 W +/- 3.46 W) was found in the "persistence trained" group, followed by the "healthy subjects" (10.85 W +/- 4.19 W). The smallest values were from the "patients" group (7.88 W +/- 2.95 W). The differences between the mean values of the CHD "patients" and the "persistence trained" were significant (p < 0.001). Similar comparisons of the groups of "healthy subjects" and "trained persons" and "healthy subjects" and "patients", respectively, yield p values of p = 0.007 and p = 0.040. These differences are also significant. This study is a first investigation and description of the method. A validation only can be achieved by follow-up investigations.
authors.affiliation: HELIOS Klinikum Erfurt GmbH III. Medizinische Klinik, Erfurt, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Salzer
authors.forename: I
authors.initials: I
authors.lastname: Bradl
authors.forename: W
authors.initials: W
authors.lastname: Mey
authors.forename: W
authors.initials: W
authors.lastname: Schneider
authors.forename: R
authors.initials: R
authors.lastname: Grieshaber
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D003327:Coronary Disease / Q000175:diagnosis / Q000503:physiopathology; D006333:Heart Failure / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D010809:Physical Fitness / Q000502:physiology; D011379:Prognosis; D012016:Reference Values; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology