A short, highly efficient synthesis of coenzyme Q(10).
The most efficient synthesis reported to date of ubiquinone (CoQ10) is described. A sequence consisting of six operations is involved which leads to crystalline material in an overall yield of >64%.
Lipshutz
Bruce H
BH
Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA. lipshutz@chem.ucsb.edu
Mollard
Paul
P
Pfeiffer
Steven S
SS
Chrisman
Will
W
D003067:Coenzymes; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000138:chemical synthesis*
D003067:Coenzymes; D014451:Ubiquinone; C024989:coenzyme Q10