Osteonecrosis of the maxilla as a complication to chemotherapy: a case report.
Numerous oral complications have been documented as a consequence of chemotherapy for the treatment of cancer. One not so well documented consequence of this treatment is avascular necrosis or osteonecrosis of the underlying bone. In this case report, osteonecrosis of the maxilla in a 48-year-old female patient who was treated for acute myelogenous leukemia is presented. The patient had successfully completed both induction and consolidation chemotherapy without steroid administration. Possible causes and difficulties in diagnosis were reviewed.
Sung
Eric C
EC
Department of Hospital Dentistry, Center for the Health Sciences, UCLA School of Dentistry, Los Angeles, CA 90095-1668, USA. ericsung@ucla.edu
Chan
Stephen M
SM
Sakurai
Karl
K
Chung
Evelyn
E
D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects; D000935:Antifungal Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D000998:Antiviral Agents / Q000009:adverse effects; D000044:Dental Abutments; D003830:Denture, Partial, Fixed; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015255:Idarubicin / Q000009:adverse effects; D016867:Immunocompromised Host; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008439:Maxillary Diseases / Q000139:chemically induced* / Q000601:surgery; D008875:Middle Aged; D010020:Osteonecrosis / Q000139:chemically induced* / Q000601:surgery; D014945:Wound Healing
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D000935:Antifungal Agents; D000970:Antineoplastic Agents; D000998:Antiviral Agents; D015255:Idarubicin