title: [Candida albicans endocarditis with mycotic aneurysms of the lower leg arteries in a patient with mechanical heart valve prosthesis].
abstract: We report on a 53-year-old patient in whom the aortic and mitral valves had been replaced. This patient developed Candida albicans sepsis with mycotic aneurysms of the tibial arteries as well as cerebral emboli under immunosuppression. Dispensing with a valve replacement operation, a sustained freedom from recurrence (period of observation currently 24 months) could be attained with antimycotic therapy with amphotericin B and flucytosine i.v. and subsequent long-term therapy with fluconazole p.o. as well as surgical and interventional clearance of the mycotic aneurysms.
authors.affiliation: Kardiologische Praxis Schlossgarten Schlossgarten 7 22041 Hamburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Kindel
authors.forename: R
authors.initials: R
authors.lastname: Sternfeldt
authors.forename: P
authors.initials: P
authors.lastname: Spiller
mesh_terms: D000328:Adult; D000785:Aneurysm, Infected / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000792:Angiography; D000935:Antifungal Agents / Q000008:administration & dosage; D001022:Aortic Valve Insufficiency / Q000601:surgery*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004696:Endocarditis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D008134:Long-Term Care; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D016909:Tibial Arteries
chemical_list: D000935:Antifungal Agents