title: Iris configuration in accommodation in pigment dispersion syndrome.
abstract: OBJECTIVE
  This study was conducted in order to investigate the effect of accommodation on the iris morphology and iridolenticular contact, in eyes with Pigment Dispersion Syndrome and Pigmentary Glaucoma, using high-resolution ultrasound.
  
  
  METHODS
  We performed a prospective observational study, examining a group of 30 Pigment Dispersion Syndrome and Pigmentary Glaucoma patients (49 eyes) and a smaller group of eight 'normals' non-Pigment Dispersion Syndrome patients (8 eyes). All patients underwent ultrasound biomicroscopy, before and during accommodation.
  
  
  RESULTS
  The iris profile before accommodation was found convex in 48.5%, flat in 19.7% and concave in 31.8%. Following accommodation the iris configuration remained unchanged in 66.2%, increased in concavity in 20.3% and decreased in concavity in 13.5%.
  
  
  CONCLUSIONS
  The effect of accommodation on iris configuration and accommodation is highly variable. From our experience the measurement of iris configuration using ultrasound biomicroscopy may not be a useful method of evaluating the effect of different treatments on iris configuration.
authors.affiliation: Moorfields Eye Hospital, London, UK. balidis@otenet.gr
authors.forename: M O
authors.initials: MO
authors.lastname: Balidis
authors.forename: C
authors.initials: C
authors.lastname: Bunce
authors.forename: C J
authors.initials: CJ
authors.lastname: Sandy
authors.forename: R P L
authors.initials: RP
authors.lastname: Wormald
authors.forename: M H
authors.initials: MH
authors.lastname: Miller
mesh_terms: D000065:Accommodation, Ocular; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D017889:Exfoliation Syndrome / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007498:Iris / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014463:Ultrasonography