title: Antimycobacterial activity of lipodepsipeptides produced by Pseudomonas syringae pv syringae B359.
abstract: Some lipodepsipeptides produced by Pseudomonas syringae pv. syringae showed strong antimycobacterial activity towards Mycobacterium smegmatis. MIC values found were between 1.5-3.2 microg/ml, which is comparable to some primary drugs for tuberculosis. Among the lipodepsipeptides, Syringomycin E (SRE) appears to be the most potent antimycobacterial agent.
authors.affiliation: Department of Biochemistry, Faculty of Medicine, Hacettepe University, 06100 Ankara, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Buber
authors.forename: A
authors.initials: A
authors.lastname: Stindl
authors.forename: N L
authors.initials: NL
authors.lastname: Acan
authors.forename: T
authors.initials: T
authors.lastname: Kocagoz
authors.forename: R
authors.initials: R
authors.lastname: Zocher
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002855:Chromatography, Thin Layer; D004926:Escherichia coli / Q000187:drug effects; D005848:Geotrichum / Q000187:drug effects; D008074:Lipoproteins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020102:Mycobacterium smegmatis / Q000187:drug effects; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011549:Pseudomonas / Q000737:chemistry / Q000378:metabolism*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D000900:Anti-Bacterial Agents; D008074:Lipoproteins; D010456:Peptides, Cyclic; C402636:syringopeptin 22