Peripheral neuroblastoma in a newborn piglet.
Peripheral neuroblastoma (PNB) is a rare neoplasia derived from neuroepithelial cells. PNB typically presents as a greyish mass, composed of round cells with features of neuronal differentiation. Necropsy, performed on a 1-day-old piglet, revealed a mass craniodorsally located in the abdominal cavity. Histologically, the predominant population consisted of small round to ovoid cells with scanty cytoplasm and dark round nuclei, besides, there were larger neurone-like cells. Neurone-specific enolase and S-100 protein were immunohistochemically detected, while glial fibrillary acidic protein was negative. Histological and immunohistochemical findings substantiated the diagnosis of a grade II peripheral neuroblastoma. This seems to be the first description of a PNB in a newborn piglet.
Diessler
M E
ME
Institute of Pathology, Veterinary School, National University of La Plata, La Plata, Argentina. diessler@fcv.medvet.unlp.edu.ar
Idiart
J R
JR
Massone
A R
AR
Machuca
M A
MA
Perfumo
C J
CJ
D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D001344:Autopsy; D003937:Diagnosis, Differential; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D009447:Neuroblastoma / Q000175:diagnosis / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis* / Q000473:pathology