NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH.
Polshakov
Vladimir I
VI
Smirnov
Eugeni G
EG
Birdsall
Berry
B
Kelly
Geoff
G
Feeney
James
J
D001665:Binding Sites; D007780:Lacticaseibacillus casei / Q000201:enzymology*; D008958:Models, Molecular; D009249:NADP / Q000737:chemistry* / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011485:Protein Binding; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D013762:Tetrahydrofolate Dehydrogenase / Q000737:chemistry* / Q000378:metabolism; D014295:Trimethoprim / Q000737:chemistry* / Q000378:metabolism
D009249:NADP; D014295:Trimethoprim; D013762:Tetrahydrofolate Dehydrogenase