title: Clerodane diterpenes from Baccharis sagittalis: insect antifeedant activity.
abstract: Two clerodane-type diterpene glycosides esters, which were studied as peracetyl derivatives, together with the known diterpene marrubiagenine, were isolated from the aerial part of Baccharis sagittalis (Less). Their structures were established by spectroscopic methods. Antifeedant activity toward Tenebrio molitor larvae of the isolated compounds along with six other diterpenes was evaluated and some structure-antifeedant bioactivity relationships are reported.
authors.affiliation: INTEQUI-CONICET-Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Chacabuco y Pedernera-5700-San Luis, Argentina.
authors.forename: Diego A
authors.initials: DA
authors.lastname: Cifuente
authors.forename: Eduardo J
authors.initials: EJ
authors.lastname: Borkowski
authors.forename: Marta E
authors.initials: ME
authors.lastname: Sosa
authors.forename: José C
authors.initials: JC
authors.lastname: Gianello
authors.forename: Oscar S
authors.initials: OS
authors.lastname: Giordano
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Tonn
mesh_terms: D000818:Animals; D031175:Baccharis / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology*; D045785:Diterpenes, Clerodane; D005247:Feeding Behavior / Q000187:drug effects; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D013712:Tenebrio / Q000187:drug effects
chemical_list: D004224:Diterpenes; D045785:Diterpenes, Clerodane; D007306:Insecticides