Stereospecific synthesis of highly substituted skipped dienes through multifunctional palladium catalysis.
[reaction: see text] Multifunctional palladium catalysis is utilized in the one-pot stereocontrolled synthesis of tetrasubstituted alkenes. The homogeneous palladium dihalide catalyst utilized for bromo-/chloroallylation of alkynes is then reused in situ for a subsequent Suzuki cross-coupling reaction.
Thadani
Avinash N
AN
Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
Rawal
Viresh H
VH
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry*; D017605:Bromine Compounds / Q000737:chemistry; D002384:Catalysis; D017606:Chlorine Compounds / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D017605:Bromine Compounds; D017606:Chlorine Compounds; D010165:Palladium