title: Safety and efficacy of cutting balloon angioplasty: the Mayo Clinic experience.
abstract: A number of evolving clinical indications for cutting balloon angioplasty (CBA) have been described in the clinical literature, including angioplasty-resistant stenoses, in-stent restenosis, ostial lesions and small vessel disease.
  
  
  METHODS
  We analyzed the Mayo Clinic PTCA registry and report procedural and in-hospital clinical outcomes in 100 patients (103 procedures, 114 lesions) undergoing CBA.
  
  
  RESULTS
  CBA was successfully completed in 109 lesions (96%). The majority of lesions (73%) required additional treatment with either balloon angioplasty (39%) or stent implantation (34%). Severe intimal dissection resulting in at least 50% luminal obstruction occurred in 13 lesions (11%). A single incident of branch occlusion was documented, resulting in ST elevation myocardial infarction. There were no incidents of vessel perforation, urgent percutaneous or surgical target vessel revascularization, or in-hospital death.
  
  
  CONCLUSIONS
  CBA is feasible and safe, with a low incidence of procedural complications and in-hospital adverse cardiac events when used primarily for in-stent restenosis.
authors.affiliation: Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: James L
authors.initials: JL
authors.lastname: Orford
authors.forename: Panayotis
authors.initials: P
authors.lastname: Fasseas
authors.forename: Ali E
authors.initials: AE
authors.lastname: Denktas
authors.forename: LaVon
authors.initials: L
authors.lastname: Hammes
authors.forename: Kirk N
authors.initials: KN
authors.lastname: Garratt
authors.forename: Peter B
authors.initials: PB
authors.lastname: Berger
authors.forename: David R
authors.initials: DR
authors.lastname: Holmes
authors.forename: Gregory W
authors.initials: GW
authors.lastname: Barsness
mesh_terms: D000046:Academic Medical Centers; D000368:Aged; D000789:Angina, Unstable / Q000000981:diagnostic imaging / Q000628:therapy*; D000800:Angioplasty, Balloon / Q000295:instrumentation* / Q000379:methods; D017023:Coronary Angiography; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008910:Minnesota; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000628:therapy*; D011379:Prognosis; D012042:Registries; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D015607:Stents; D016896:Treatment Outcome