title: Clinical, epidemiological, and socioeconomic analysis of an outbreak of Vibrio parahaemolyticus in Khanh Hoa Province, Vietnam.
abstract: From 1996 onward, a pandemic spread of Vibrio parahaemolyticus infections due to one clone has been reported in several Asian countries. During a population-based study that relied on passive surveillance, 548 cases of V. parahaemolyticus infection were detected between 1997 and 1999 in the Khanh Hoa province of Vietnam. Detection of cases of V. parahaemolyticus infection abruptly stopped in November 1999, although Vibrio species other than V. parahaemolyticus continued to be isolated throughout 2000. Of the infections, 90% occurred in individuals >5 years old; 53% of the patients presented with watery stools, and 6% reported blood in their stools. All patients had recovered by the time of discharge. A surprising risk factor for V. parahaemolyticus infections was high socioeconomic status. Like the interruption of the transmission of V. cholerae infections that had been observed earlier, the transmission of V. parahaemolyticus came to a halt without meteorological changes or changes in water supply and sanitation.
authors.affiliation: Institute Pasteur, Nha Trang, Vietnam.
authors.forename: Dinh Thi
authors.initials: DT
authors.lastname: Tuyet
authors.forename: Vu Dinh
authors.initials: VD
authors.lastname: Thiem
authors.forename: Lorenz
authors.initials: L
authors.lastname: Von Seidlein
authors.forename: Ashrafazzuman
authors.initials: A
authors.lastname: Chowdhury
authors.forename: Eunsik
authors.initials: E
authors.lastname: Park
authors.forename: Do Gia
authors.initials: DG
authors.lastname: Canh
authors.forename: Bui Trong
authors.initials: BT
authors.lastname: Chien
authors.forename: Tran
authors.initials: T
authors.lastname: Van Tung
authors.forename: Abdollah
authors.initials: A
authors.lastname: Naficy
authors.forename: Malla Raghav
authors.initials: MR
authors.lastname: Rao
authors.forename: Mohammad
authors.initials: M
authors.lastname: Ali
authors.forename: Hyejon
authors.initials: H
authors.lastname: Lee
authors.forename: Trinh Hung
authors.initials: TH
authors.lastname: Sy
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Nichibuchi
authors.forename: John
authors.initials: J
authors.lastname: Clemens
authors.forename: Dang Duc
authors.initials: DD
authors.lastname: Trach
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012959:Socioeconomic Factors; D014735:Vibrio Infections / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology*; D014736:Vibrio parahaemolyticus / Q000302:isolation & purification*; D014744:Vietnam / Q000453:epidemiology