Alpha 2-adrenoceptor stimulation in the periventricular nucleus increases urine flow rate with minimal effects on blood pressure.
Penner
S Brian
SB
Departments of Pharmacology & Therapeutics and Internal Medicine, University of Manitoba, 753 McDermot Avenue, Winnipeg, Manitoba, Canada R3E 0T6. bpenner@cc.umanitoba.ca
Mueller
Heather A
HA
Smyth
Donald D
DD
D058647:Adrenergic alpha-2 Receptor Agonists; D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D016316:Guanfacine / Q000494:pharmacology; D008297:Male; D020644:Midline Thalamic Nuclei / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012964:Sodium / Q000652:urine; D013268:Stimulation, Chemical; D014563:Urodynamics / Q000187:drug effects*
D058647:Adrenergic alpha-2 Receptor Agonists; D000316:Adrenergic alpha-Agonists; D016316:Guanfacine; D012964:Sodium