The spectrum of computerized tomography (CT) findings in central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii in immunocompetent children.
Cranial CT scans of eleven immunocompetent children with central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii were retrospectively reviewed. These children had an average age of 8.8 years and positive culture for C. n. var. gattii in cerebrospinal fluid. The most common signs and symptoms were headache, fever, nuchal rigidity, nausea and vomiting. No normal cranial CT was detected in any patient. Hypodense nodules were observed in all patients. The remaining scan abnormalities were as follows: nine had diffuse atrophy, six had hydrocephalus, and five had hydrocephalus coexistent with diffuse atrophy.
Correa
Maria do Perpétuo Socorro Costa
Mdo P
Núcleo de Medicina Tropical, Universidade Federal do Pará, PA, Brasil.
Severo
Luiz Carlos
LC
Oliveira
Flávio de Mattos
Fde M
Irion
Klaus
K
Londero
Alberto Thomaz
AT
D001927:Brain Diseases / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging* / Q000382:microbiology; D020314:Central Nervous System Fungal Infections / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging* / Q000382:microbiology; D002648:Child; D003453:Cryptococcosis / Q000134:cerebrospinal fluid / Q000532:radiotherapy*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed