title: Superoxide dismutase activity and electrochemical study of the binuclear [Cu(TSA)2py]2 complex.
abstract: The superoxide dismutase-mimetic activity and the electrochemical behavior of the binuclear complex [Cu(TSA)2py]2 is reported. The complex exhibits a marked SOD activity in the nitroblue tetrazolium assay. Its redox response is in agrement with two copper atoms partially coupled through the carboxylate moieties. The electrode reactions lie in the range of the superoxide/peroxide and oxygen/superoxide couples. This fact is indicative that this complex can act as catalyst for the SOD reaction.
authors.affiliation: Centro de Química Inorgánica, Facultad de Ciencias Exactas, UNLP, La Plata, Argentina.
authors.forename: Beatriz Susana
authors.initials: BS
authors.lastname: Parajón Costa
authors.forename: Roxana Maria
authors.initials: RM
authors.lastname: Tótaro
authors.forename: Evelina Gloria
authors.initials: EG
authors.lastname: Ferrer
authors.forename: Patricia Ana Maria
authors.initials: PA
authors.lastname: Williams
mesh_terms: D000818:Animals; D002384:Catalysis; D002417:Cattle; D003300:Copper / Q000737:chemistry* / Q000494:pharmacology; D004563:Electrochemistry; D004912:Erythrocytes / Q000201:enzymology; D007202:Indicators and Reagents / Q000494:pharmacology; D008956:Models, Chemical; D009580:Nitroblue Tetrazolium / Q000494:pharmacology; D009942:Organometallic Compounds / Q000737:chemistry* / Q000494:pharmacology; D010084:Oxidation-Reduction; D010100:Oxygen / Q000378:metabolism; D012459:Salicylates / Q000378:metabolism; D013438:Sulfhydryl Compounds; D013482:Superoxide Dismutase / Q000378:metabolism*; D013816:Thermodynamics
chemical_list: D007202:Indicators and Reagents; D009942:Organometallic Compounds; D012459:Salicylates; D013438:Sulfhydryl Compounds; D009580:Nitroblue Tetrazolium; D003300:Copper; C441201:thiosalicylic acid; D013482:Superoxide Dismutase; D010100:Oxygen