title: A knowledge representation view on biomedical structure and function.
abstract: In biomedical ontologies, structural and functional considerations are of outstanding importance, and concepts which belong to these two categories are highly interdependent. At the representational level both axes must be clearly kept separate in order to support disciplined ontology engineering. Furthermore, the biaxial organization of physical structure (both by a taxonomic and partonomic order) entails intricate patterns of inference. We here propose a layered encoding of taxonomic, partonomic and functional aspects of biomedical concepts using description logics.
authors.affiliation: Frieberg University Hospital, Departement of Medical Informatics, Freiburg 79104, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Schulz
authors.forename: Udo
authors.initials: U
authors.lastname: Hahn
mesh_terms: D001185:Artificial Intelligence; D001695:Biology; D008128:Logic; D008490:Medical Informatics; D018875:Vocabulary, Controlled