title: Surface-modified carbon felts: possible supports for combinatorial chemistry.
abstract: It is possible to prepare carbon-based analogues of the Merrifield resin by electrochemical reduction of diazonium salts or oxidation of aryl acetates on high specific surface area carbon felts. These modified felts can undergo further reactions: nucleophilic substitution, Suzuki reaction, and finally reductive electrochemical cleavage, taking advantage of the conductivity of the carbon felt. This provides a simple example of the possible use of electrochemistry in combinatorial synthesis.
authors.affiliation: Centre de Recherche de Vitry, Aventis Pharma, 13 Quai Jules Guesdes, BP14, 94403 Vitry sur Seine Cedex, France.
authors.forename: Estelle
authors.initials: E
authors.lastname: Coulon
authors.forename: Jean
authors.initials: J
authors.lastname: Pinson
authors.forename: Jean-Dominique
authors.initials: JD
authors.lastname: Bourzat
authors.forename: Alain
authors.initials: A
authors.lastname: Commerçon
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Pulicani