[The effect of NO-synthase inhibition on the blood oxygen transport function during fever in rabbits].
I.v. administration of NG-nitro-L-arginine attenuated a fever response in rabbit. Preliminary administration of L-arginine for prevention of the NO-synthase inhibition suppressed the blood oxygen transport function and augmented the fever response.
Zinchuk
V V
VV
State Medical Institute, 230015, Grodno, Gorky St., 80, Russia.
Borisiuk
M V
MV
D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005334:Fever / Q000097:blood*; D008297:Male; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors*; D019335:Nitroarginine / Q000494:pharmacology; D010100:Oxygen / Q000097:blood*; D011817:Rabbits
D004791:Enzyme Inhibitors; D019335:Nitroarginine; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D010100:Oxygen