title: Metastatic endodermal sinus tumor: CT appearances.
abstract: A one-week-old boy had undergone resection of a sacrococcygeal benign cystic teratoma. At the age of 12 months, he had a serum alpha-fetoprotein level of 139,000 IU/ml and a recurrent pelvic mass which was removed, and the microscopic examination revealed endodermal sinus tumor. Postoperatively, massively enlarged inguinal lymph nodes and abdominal distention developed. Computerized tomography displayed enlarged inguinal lymph nodes, metastatic lesions in the liver, and a pelvic recurrent mass. He received BEP (bleomycin, etoposide, cisplatin) chemotherapy regimen, and a complete remission was achieved with a normal serum alpha-fetoprotein. Close follow-up and serum alpha-fetoprotein monitoring are mandatory after the resection of a sacrococcygeal teratoma.
authors.affiliation: Department of Pediatric Oncology, Institute of Oncology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Bilgehan
authors.initials: B
authors.lastname: Yalçin
authors.forename: M Tezer
authors.initials: MT
authors.lastname: Kutluk
authors.forename: Macit
authors.initials: M
authors.lastname: Ariyürek
authors.forename: Safiye
authors.initials: S
authors.lastname: Göğüş
authors.forename: Münevver
authors.initials: M
authors.lastname: Büyükpamukçu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D018240:Endodermal Sinus Tumor / Q000000981:diagnostic imaging* / Q000556:secondary / Q000628:therapy; D005047:Etoposide / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000628:therapy; D010386:Pelvic Neoplasms / Q000000981:diagnostic imaging*; D012445:Sacrococcygeal Region; D014057:Tomography, X-Ray Computed; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin