Cessation of smoking and drinking and the risk of laryngeal cancer.
A case-control study was conducted in Italy and Switzerland between 1992 and 2000 on 527 cases of laryngeal cancer and 1,297 hospital controls. The risk of laryngeal cancer steadily decreased from 3 years after stopping smoking. Some decline in risk was observed only 20 years or more after stopping drinking.
Altieri
A
A
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy. altieri@marionegri.it
Bosetti
C
C
Talamini
R
R
Gallus
S
S
Franceschi
S
S
Levi
F
F
Dal Maso
L
L
Negri
E
E
La Vecchia
C
C
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D007822:Laryngeal Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation; D013557:Switzerland / Q000453:epidemiology