title: Proximal aortic reoperations in patients with composite valve grafts.
abstract: BACKGROUND
  The purpose of this study was to examine our experience with proximal aortic reoperations in patients with composite valve grafts (CVGs) and assess postoperative survival and morbidity.
  
  
  METHODS
  Since 1991, 33 patients with CVGs underwent reoperation for one or more of the following indications: aneurysms distal to the CVG (n = 20, 61%), false aneurysms (n = 13, 39%) and graft infection (n = 7, 21%). Operations included false aneurysm repair (n = 13, 39%), graft replacement of distal ascending aortic or transverse aortic arch aneurysm (n = 20, 61%) and aortic root re-replacement with a new CVG (n = 6, 18%) or homograft (n = 4, 12%).
  
  
  RESULTS
  Operative mortality was 15% (n = 5), including 2 of the 7 patients who had infected CVGs (29%). All 4 patients who had infected CVGs replaced with aortic root homografts survived. Complications included vocal cord paralysis (n = 4, 12%), bleeding requiring reoperation (n = 3, 9%) and stroke (n = 2, 6%). Actuarial 3-year survival was 74.4% +/- 7.9%.
  
  
  CONCLUSIONS
  Reoperations in patients with CVGs remain challenging procedures with high associated morbidity and mortality, especially in the setting of graft infection. The results of homograft aortic root re-replacement for infected CVGs are encouraging.
authors.affiliation: The Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA. slemaire@bcm.tmc.edu
authors.forename: Scott A
authors.initials: SA
authors.lastname: LeMaire
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: DiBardino
authors.forename: Cüneyt
authors.initials: C
authors.lastname: Köksoy
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Coselli
mesh_terms: D000328:Adult; D000368:Aged; D017541:Aneurysm, False / Q000401:mortality / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000401:mortality / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000401:mortality / Q000601:surgery; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality / Q000601:surgery*; D016459:Prosthesis-Related Infections / Q000401:mortality / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation / Q000401:mortality; D012307:Risk Factors; D014184:Transplantation, Homologous