Quantitative assessment of nitric oxide in rat skeletal muscle and plasma after exercise.
Nitric oxide (NO), a short-lived vasoactive substance that has multiple physiological functions, is also involved in skeletal muscle physiology. This work examines the levels of nitrate (the metabolic end-product of NO) in muscle and plasma after different exercise protocols: namely acute, eccentric, cardiac stress and training. Plasma nitrate levels were augmented after strenuous exercise and did not change after training. The vastus intermedius and the gastrocnemius, both oxidative muscles, showed the highest concentrations of cytosolic nitrate after strenuous exercise. NO levels varied, depending on the fibre type, and this may correlate well with the specific contractile function performed.
Perez
Andrea C
AC
Department of Physiology, Faculty of Veterinary Science Universidad de Leon, Leon, 24071 Spain.
de Oliveira
Cesar Cabral
CC
Prieto
Julio G
JG
Ferrando
Ana
A
Vila
Luzdivina
L
Alvarez
Ana I
AI
D000818:Animals; D003600:Cytosol / Q000378:metabolism; D007866:Leg; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D018482:Muscle, Skeletal / Q000378:metabolism*; D009566:Nitrates / Q000097:blood / Q000378:metabolism; D009569:Nitric Oxide / Q000097:blood / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D010807:Physical Endurance; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D009566:Nitrates; D009569:Nitric Oxide