title: History of cardiac rhythm disorders.
abstract: The history of cardiac rhythm disorders including antiarrhythmic drugs and electrotherapeutical tools is long and fascinating. In the beginning, there was not simply the anatomy and physiology of the heart, but also analysis of the pulse, which indicates the activity of the heart. Thus, like any other field of medicine, the study of arrhythmias has a distinctive past. Our current level of knowledge is not the result of a straight, linear progression any more than there is a static, established, monolithic body of thought dominating this field. Instead, our knowledge of arrhythmias today is the result of many competitive, sometimes serendipitous, scientific realizations, of which a few proved useful enough to pursue and eventually led to real advancements. Looking at the worldwide development of rhythmology it can be said that considerable contributions came from Germany in the last few centuries. Arrhythmology--past, present and future--includes clearly German investigators as pioneers of the field. The growing clinical importance of electric cardiac stimulation has been recognized and renewed as Zoll in 1952 described a successful resuscitation in cardiac standstill by external stimulation. The concept of a fully automatic implantable cardioverter-defibrillator system for recognition and treatment of ventricular flutter/fibrillation was first suggested in 1970. The first implantation of the device in a human being was performed in February 1980. By early 1997, 17 years after the first human implantation more than 100,000 ICD systems had been implanted worldwide. Further developments concern new pharmacological compounds, modern cardioverter-defibrillators, radiofrequency ablation, particularly pulmonary vein ablation in atrial fibrillation, innovative pacemakers including preventive pacing techniques, probably laser therapy and perhaps the automatic implantable pharmacological defibrillator. The advances in the field of therapeutic application of pharmacologic and electrical means as well as alternative methods will continue as rapidly as before in order to give us further significant aid in taking care of the patient.
authors.affiliation: Medizinische Klinik und Poliklink II Universitätsklinikum Bonn Sigmund-Freud-Str. 25 D-53105 Bonn.
authors.forename: B
authors.initials: B
authors.lastname: Lüderitz
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000266:history* / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000266:history* / Q000628:therapy; D002304:Cardiac Pacing, Artificial / Q000266:history*; D002309:Cardiology / Q000266:history; D017115:Catheter Ablation / Q000266:history*; D003226:Congresses as Topic / Q000266:history; D004554:Electric Countershock / Q000266:history*; D005858:Germany; D049673:History, 20th Century; D006801:Humans; D012955:Societies, Medical / Q000266:history
chemical_list: D000889:Anti-Arrhythmia Agents