Clinical, epidemiological, and socioeconomic analysis of an outbreak of Vibrio parahaemolyticus in Khanh Hoa Province, Vietnam.
From 1996 onward, a pandemic spread of Vibrio parahaemolyticus infections due to one clone has been reported in several Asian countries. During a population-based study that relied on passive surveillance, 548 cases of V. parahaemolyticus infection were detected between 1997 and 1999 in the Khanh Hoa province of Vietnam. Detection of cases of V. parahaemolyticus infection abruptly stopped in November 1999, although Vibrio species other than V. parahaemolyticus continued to be isolated throughout 2000. Of the infections, 90% occurred in individuals >5 years old; 53% of the patients presented with watery stools, and 6% reported blood in their stools. All patients had recovered by the time of discharge. A surprising risk factor for V. parahaemolyticus infections was high socioeconomic status. Like the interruption of the transmission of V. cholerae infections that had been observed earlier, the transmission of V. parahaemolyticus came to a halt without meteorological changes or changes in water supply and sanitation.
Tuyet
Dinh Thi
DT
Institute Pasteur, Nha Trang, Vietnam.
Thiem
Vu Dinh
VD
Von Seidlein
Lorenz
L
Chowdhury
Ashrafazzuman
A
Park
Eunsik
E
Canh
Do Gia
DG
Chien
Bui Trong
BT
Van Tung
Tran
T
Naficy
Abdollah
A
Rao
Malla Raghav
MR
Ali
Mohammad
M
Lee
Hyejon
H
Sy
Trinh Hung
TH
Nichibuchi
Mitsuaki
M
Clemens
John
J
Trach
Dang Duc
DD
D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012959:Socioeconomic Factors; D014735:Vibrio Infections / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology*; D014736:Vibrio parahaemolyticus / Q000302:isolation & purification*; D014744:Vietnam / Q000453:epidemiology