title: [Psoriasis and autoimmune skin disorders].
abstract: BACKGROUND
  Presuming that psoriasis is an autoimmune skin disease, the aim of this study was to establish its association with other autoimmune skin diseases. The material was obtained at the Dermatovenereological Clinic--Clinical Center Novi Sad.
  
  
  METHODS
  This 10-year retrospective study (1990-1999) included 1743 psoriasis patients. The control group consisted of 7492 nonpsoriatic dermatological patients.
  
  
  RESULTS
  Association of psoriasis with other dermatological diseases of autoimmune nature has been established in 13 (0.74%) patients. The most frequent association was with lichen ruber planus in five patients, with alopecia areata and vitiligo in three patients, and in one with bullous pemphigoid and herpetiform dermatitis. Using Fisher's test no significant association was established.
  
  
  CONCLUSIONS
  According to literature data association of psoriasis with other autoimmune diseases is well known, but rare, which is in accordance with our results. The question arises whether this association is the matter of poor coexistence or the matter of genetic mutations. However, once established, these associations can further highlight the autoimmune nature of psoriasis. The research of autoimmunity would lead us to epithelial cells in thymus, and their badly learnt cognitive function about what is own, and what is not.
authors.affiliation: Klinika za kozno-venericne bolesti, 21000 Novi Sad, Hajduk Veljkova 1-3. cojans@eunet.yu
authors.forename: Mirjana
authors.initials: M
authors.lastname: Poljacki
authors.forename: Mirjana
authors.initials: M
authors.lastname: Begenesić
authors.forename: Verica
authors.initials: V
authors.lastname: Duran
authors.forename: Ljubinka
authors.initials: L
authors.lastname: Matović
authors.forename: Milan
authors.initials: M
authors.lastname: Matić
authors.forename: Marina
authors.initials: M
authors.lastname: Jovanović
authors.forename: Slobodan
authors.initials: S
authors.lastname: Stojanović
authors.forename: Tatjana
authors.initials: T
authors.lastname: Ros
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D012189:Retrospective Studies