title: [Review of relationship between vascular endothelial growth factor C & D and lymph node metastasis of malignant tumor].
abstract: The mechanism and inhibition of lymph node metastasis of malignant tumor are one of the research hot points. There are many researches indicating that vascular endothelial growth factor-C(VEGF-C) and vascular endothelial growth factor-D(VEGF-D) were closely associated with lymph node metastasis of malignant tumor. This article mainly reviewed the structures, functional characteristics, possible mechanisms of VEGF-C and VEGF-D in lymph node metastasis, and current progress of inhibition of lymph node metastasis of malignant tumor.
authors.affiliation: Department of Head & Neck, Cancer Center, Sun Yat-sen University, Guangzhou 510060, P. R. China. Liq99@163.net
authors.forename: Qiu-li
authors.initials: QL
authors.lastname: Li
authors.forename: Fu-jing
authors.initials: FJ
authors.lastname: Chen
mesh_terms: D016228:Endothelial Growth Factors / Q000378:metabolism*; D006801:Humans; D008207:Lymphatic Metastasis; D042582:Vascular Endothelial Growth Factor C; D042643:Vascular Endothelial Growth Factor D
chemical_list: D016228:Endothelial Growth Factors; D042582:Vascular Endothelial Growth Factor C; D042643:Vascular Endothelial Growth Factor D