title: [Respiratory support with high frequency jet ventilation in severely burned patients with inhalation injury during early postburn stage].
abstract: OBJECTIVE
  To observe the effects of respiratory support with high frequency jet ventilation (HFJV) in severely burned patients with inhalation injury during early postburn stage.
  
  
  METHODS
  Twenty severely burned patients with TBSA of 79.6 +/- 29.3% and inhalation injury were enrolled in the study. Nineteen cases received tracheostomy after admission and only one received nasal intubation. All the patients underwent HFJV to correct hypoxia. The changes in blood gas analysis, respiratory rate and pulse were recorded before and 11 days after the ventilation.
  
  
  RESULTS
  Tracheostomy was performed on 2.7 +/- 2.4 postburn days (PBDs), and HFJV was given during 4.4 +/- 2.9 PBDs. PaO(2) was evidently higher during 1 - 3 days after HFJV than that before the ventilation (P < 0.01) and remained at high level for 1 week after HFJV. There was no change in PaCO(2), respiratory rate and pulse during the ventilation.
  
  
  CONCLUSIONS
  HFJV was beneficial in improving oxygenation and without any obvious side effects during the early management of severely burned patients with inhalation injury. This might be an optimal respiratory support pattern.
authors.affiliation: Department of Burns, The First Affiliated Hospital, Jiang Xi Medical College, Nanchang, 330006, Jiang Xi Province, P.R. China.
authors.forename: Guanghua
authors.initials: G
authors.lastname: Guo
authors.forename: Yu
authors.initials: Y
authors.lastname: Li
authors.forename: Zilan
authors.initials: Z
authors.lastname: Liu
authors.forename: Kunwu
authors.initials: K
authors.lastname: Fan
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhao
authors.forename: Lixin
authors.initials: L
authors.lastname: Liao
authors.forename: Yurong
authors.initials: Y
authors.lastname: Yu
authors.forename: Hongming
authors.initials: H
authors.lastname: Yang
authors.forename: Dinghong
authors.initials: D
authors.lastname: Min
authors.forename: Shangji
authors.initials: S
authors.lastname: Liu
authors.forename: Guohui
authors.initials: G
authors.lastname: Li
mesh_terms: D000328:Adult; D001784:Blood Gas Analysis; D002056:Burns / Q000150:complications* / Q000601:surgery; D006611:High-Frequency Jet Ventilation; D006801:Humans; D008875:Middle Aged; D015208:Smoke Inhalation Injury / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D014139:Tracheostomy