Antitrichomonal strains of Bacillus thuringiensis.
Parasporal inclusion proteins from a total of 816 Bacillus thuringiensis strains isolated in Japan were examined for antitrichomonal activity against Trichomonas vaginalis. Ten strains of B. thuringiensis inhibited the growth of T. vaginalis in 48 h cultures at 37 degrees C. Moreover, the B622 and B626 strains clearly showed trichomonacidal effects against T. vaginalis. The H antigen serotypes of both strains were identified as H13/29 (pakistani/amagiensis). The parasporal inclusion protein from both strains consisted of three major polypeptides of 77, 45 and 25 kDa.
Kondo
Shigeo
S
Department of Parasitology, Aichi Medical University School of Medicine, Nagakute, Aichi, 480-1195, Japan. kondo@aichi-med-u.ac.jp
Mizuki
Eiichi
E
Akao
Tetsuyuki
T
Ohba
Michio
M
D000818:Animals; D000994:Antitrichomonal Agents / Q000494:pharmacology*; D001413:Bacillus thuringiensis / Q000737:chemistry*; D001426:Bacterial Proteins / Q000032:analysis; D002478:Cells, Cultured; D004731:Endotoxins / Q000494:pharmacology*; D005260:Female; D006801:Humans; D012988:Soil Microbiology; D014247:Trichomonas Vaginitis / Q000188:drug therapy*; D014246:Trichomonas vaginalis / Q000187:drug effects* / Q000254:growth & development
D000994:Antitrichomonal Agents; D001426:Bacterial Proteins; D004731:Endotoxins; C412914:parasporin