title: NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH.
authors.forename: Vladimir I
authors.initials: VI
authors.lastname: Polshakov
authors.forename: Eugeni G
authors.initials: EG
authors.lastname: Smirnov
authors.forename: Berry
authors.initials: B
authors.lastname: Birdsall
authors.forename: Geoff
authors.initials: G
authors.lastname: Kelly
authors.forename: James
authors.initials: J
authors.lastname: Feeney
mesh_terms: D001665:Binding Sites; D007780:Lacticaseibacillus casei / Q000201:enzymology*; D008958:Models, Molecular; D009249:NADP / Q000737:chemistry* / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011485:Protein Binding; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D013762:Tetrahydrofolate Dehydrogenase / Q000737:chemistry* / Q000378:metabolism; D014295:Trimethoprim / Q000737:chemistry* / Q000378:metabolism
chemical_list: D009249:NADP; D014295:Trimethoprim; D013762:Tetrahydrofolate Dehydrogenase