title: [A case report of two siblings. Cardiac angiosarcoma--rare tumor with non-specific symptoms and poor prognosis].
abstract: Primary cardiac malignancy is rare. The most common of the malignant cardiac tumors are angiosarcomas. Diagnosis is often difficult due to the non-specific nature of symptoms and to the presentation of the disease. We review the medical literature with regard to frequency, clinical presentation, diagnosis and therapeutic options in cardiac angiosarcoma. We report the cases of a brother and sister, both diagnosed with cardiac angiosarcoma, detailing symptoms and clinical findings. Occurrence in siblings other than identical twins has not previously been described.
authors.affiliation: Medicinkliniken, Hälsinglands sjukhus, Hudiksvall. lennart.lundkvist@lg.se
authors.forename: Lennart
authors.initials: L
authors.lastname: Lundkvist
authors.forename: Hans
authors.initials: H
authors.lastname: Erntell
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D006801:Humans; D008297:Male; D011379:Prognosis; D035583:Rare Diseases / Q000175:diagnosis / Q000235:genetics / Q000473:pathology