Antifeedant activity of metabolites from Viguiera tucumanensis.
Several terpenoids and clerod-14-ene-3alpha, 4beta,13xi-triol (1), the main compound of V. tucumanensis, were isolated and bioassayed. The clerodane 1 showed higher antifeedant activity than other related compounds. Structure-activity relationships are also discussed.
Vaccarini
Clarisa E
CE
Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Instituto Multidisciplinario de Biologia Vegetal IMBIV (CONICET-UNC), Argentina.
Palacios
Sara M
SM
Meragelman
Karina M
KM
Sosa
Virginia E
VE
D000818:Animals; D019659:Asteraceae / Q000737:chemistry* / Q000378:metabolism* / Q000469:parasitology; D001681:Biological Assay; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism / Q000494:pharmacology*; D045785:Diterpenes, Clerodane; D005247:Feeding Behavior / Q000187:drug effects; D007313:Insecta / Q000187:drug effects / Q000254:growth & development; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism / Q000494:pharmacology*
D004224:Diterpenes; D045785:Diterpenes, Clerodane; D007306:Insecticides; D013729:Terpenes; C470598:clerod-14-ene-3,4,13-triol