Interruption of perfect CAG repeats by CAA triplets improves the stability of glutamine-encoding repeat sequences.
Dorsman
J C
JC
Leiden University Medical Center, The Netherlands. j.c.dorsman@lumc.nl
Bremmer-Bout
M
M
Pepers
B
B
van Ommen
G-J B
GJ
Den Dunnen
J T
JT
D003001:Cloning, Molecular; D003062:Codon; D004274:DNA, Recombinant / Q000235:genetics; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D018390:Gene Targeting / Q000379:methods; D005815:Genetic Code; D005973:Glutamine; D016297:Mutagenesis, Site-Directed; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis / Q000235:genetics; D013379:Substrate Specificity; D018911:Trinucleotide Repeats
D003062:Codon; D004274:DNA, Recombinant; D009838:Oligodeoxyribonucleotides; D005973:Glutamine; D015252:Deoxyribonucleases, Type II Site-Specific