title: Comparative evaluation of Midazolam and Propofol as intravenous sedative agents in the management of unco-operative children.
abstract: Dental treatment of very young children (toddlers) as well as children with highly negative behaviour is known to be difficult. Management of these children requires special skill and at times the support of pharmacological means. A study was planned and carried out to evaluate and compare the efficacy and safety of Propofol and Midazolam as Intravenous sedative agents in the management of uncooperative children belonging to age group 2-5 years, ASA I Category and Frankl's behaviour rating 1 and 2. The results showed both agents to be effective sedative agents, for short pedodontic procedures with minimal side effects.
authors.affiliation: Department of Pediatric and Preventive Dentistry, Nair Hospital Dental College, Mumbai, Maharashtra.
authors.forename: V S
authors.initials: VS
authors.lastname: Arya
authors.forename: S G
authors.initials: SG
authors.lastname: Damle
mesh_terms: D000766:Anesthesia, Dental; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D001794:Blood Pressure / Q000187:drug effects; D002652:Child Behavior / Q000187:drug effects*; D002675:Child, Preschool; D016292:Procedural Sedation; D003299:Cooperative Behavior; D003448:Crying; D003729:Dental Care / Q000523:psychology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D008874:Midazolam / Q000008:administration & dosage*; D009068:Movement / Q000187:drug effects; D010100:Oxygen / Q000097:blood; D015742:Propofol / Q000008:administration & dosage*; D012119:Respiration / Q000187:drug effects; D012449:Safety; D012890:Sleep / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D018686:Anesthetics, Intravenous; D006993:Hypnotics and Sedatives; D008874:Midazolam; D010100:Oxygen; D015742:Propofol