[Induction of murine bone marrow stromal cell differentiation into nerve cells].
The in vitro induced differentiation of mouse bone marrow stromal cells into nerve cells by retinoic acid and leukemia inhibitory factor has been shown, using morphological, histochemical and immunocytochemical analyses. The developed techniques allow to obtain up to 30% of neural cells in vitro. A suggestion about pluripotency of bone marrow stromal cells and possibility of their application to the cell therapy is discussed.
Shchegel'skaia
Iu E
IuE
Institute for Problems of Cryobiology and Cryomedicine, National Academy of Sciences of the Ukraine, Kharkov.
Mikulinskiĭ
Iu E
IuE
Revishchin
A V
AV
Omel'chenko
E A
EA
Kul'shin
V E
VE
Grishchenko
V I
VI
Korochkin
L I
LI
D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology*; D051379:Mice; D009474:Neurons / Q000166:cytology*; D017154:Stromal Cells / Q000166:cytology*