[Heart resistance against stress-induced damages].
Activation of peripheral-opioid receptors diminished stress-induced heart damage whereas stimulation of central-opioid receptors enhanced it. Peripheral-opioid receptors do not take part in pathogenesis of the "stress cardiomyopathy". The prostanoid system and processes of lipid peroxidation participate in realisation of cardioprotective effects associated with peripheral-opioid receptors.
Maslov
L N
LN
Institute of Cardiology, 634050 Tomsk, 24 Shevchenko St., Russia.
Naryzhnaia
N V
NV
Barbarash
N L
NL
Lishmanov
Iu B
IuB
D000818:Animals; D008297:Male; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D011957:Receptors, Opioid / Q000819:agonists / Q000378:metabolism*; D017465:Receptors, Opioid, delta / Q000819:agonists / Q000378:metabolism; D017450:Receptors, Opioid, mu / Q000819:agonists / Q000378:metabolism; D013312:Stress, Physiological / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology
D011957:Receptors, Opioid; D017465:Receptors, Opioid, delta; D017450:Receptors, Opioid, mu