Molecular differentiation of Mycobacterium tuberculosis strains without IS6110 insertions.
By using standard restriction fragment length polymorphism, 6 zero-copy IS6110 Mycobacterium tuberculosis isolates were identified from 1180 Maryland isolates as part of the National Tuberculosis Genotyping and Surveillance Network Project. By using various genotyping methods, we demonstrated that this zero band cluster can be differentiated into six genotypes.
Lok
Kerry H
KH
University of Alabama at Birmingham, Birmingham, Alabama 35294-0022, USA.
Benjamin
William H
WH
Kimerling
Michael E
ME
Pruitt
Virginia
V
Lathan
Monica
M
Razeq
Jafar
J
Hooper
Nancy
N
Cronin
Wendy
W
Dunlap
Nancy E
NE
D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D021901:DNA, Intergenic / Q000032:analysis / Q000235:genetics; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008396:Maryland / Q000453:epidemiology; D009154:Mutation / Q000235:genetics; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics*; D009841:Oligonucleotides / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length; D014376:Tuberculosis / Q000453:epidemiology / Q000382:microbiology*
D004269:DNA, Bacterial; D021901:DNA, Intergenic; D009841:Oligonucleotides