Alpha1-antitrypsin: not just an antiprotease: extending the half-life of a natural anti-inflammatory molecule by conjugation with polyethylene glycol.
Brantly
Mark
M
Department of Medicine, University of Florida, Gainesville, USA. brantml@medicine.ufl.edu
D000818:Animals; D006801:Humans; D008168:Lung / Q000276:immunology / Q000378:metabolism*; D011014:Pneumonia / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D011092:Polyethylene Glycols / Q000494:pharmacology*; D015842:Serine Proteinase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D013501:Surface-Active Agents / Q000494:pharmacology*; D000515:alpha 1-Antitrypsin / Q000737:chemistry / Q000494:pharmacology*
D015842:Serine Proteinase Inhibitors; D013501:Surface-Active Agents; D000515:alpha 1-Antitrypsin; D011092:Polyethylene Glycols