title: [Untoward side effects of chemoradiotherapy in children with malignant brain tumors].
abstract: Untoward side-effects of chemoradiotherapy were compared in 48 children treated for brain tumors and those in remission lasting from less than 12 months to 11 years. The investigation concerned disturbances in the neurologic, endocrine, cardiovascular, urinary, hepatobiliary and psychic systems; neurologic ones proved the most frequent. No cases of heart failure were reported among patients with brain tumors during remission. Hormonal study revealed inhibited thyroid function in brain tumor sufferers.
authors.affiliation: Republican Center for Pediatric Oncology and Hematology Research, Ministry of Health, Republic of Belarus, Minsk.
authors.forename: S K
authors.initials: SK
authors.lastname: Morozova
authors.forename: I V
authors.initials: IV
authors.lastname: Begun
authors.forename: L V
authors.initials: LV
authors.lastname: Spivak
authors.forename: K A
authors.initials: KA
authors.lastname: Radiuk
authors.forename: I I
authors.initials: II
authors.lastname: Papkevich
authors.forename: T V
authors.initials: TV
authors.lastname: Savich
authors.forename: E B
authors.initials: EB
authors.lastname: Pershaĭ
authors.forename: T I
authors.initials: TI
authors.lastname: Vashkevich
authors.forename: O V
authors.initials: OV
authors.lastname: Aleĭnikova
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D001523:Mental Disorders / Q000139:chemically induced / Q000209:etiology; D009422:Nervous System Diseases / Q000139:chemically induced / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D012074:Remission Induction; D013961:Thyroid Gland / Q000187:drug effects / Q000528:radiation effects; D013997:Time Factors
chemical_list: D006728:Hormones