Chronic lymphocytic leukemia presenting in association with aplastic anemia.
An unusual case of chronic lymphocytic leukemia presenting in association with aplastic anemia is discussed, along with a review of the few previously reported cases. Possible humoral and cellular autoimmune mechanisms are examined as possible causes of marrow aplasia in this setting.
Zonder
Jeffrey A
JA
Division of Hematology-Oncology, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201, USA. zonderj@karmanos.org
Keating
Michael
M
Schiffer
Charles A
CA
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000741:Anemia, Aplastic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D016572:Cyclosporine / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology
D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents; D016572:Cyclosporine