Membranoproliferative glomerulonephritis develops in a child with autologous stem cell transplant.
Bone marrow transplant nephropathy is a known complication of bone marrow transplantation. Bone marrow transplantation can cause various rare kidney diseases such as membranous nephropathy and focal segmental glomerulosclerosis. Idiopathic membranoproliferative glomerulonephritis is rare in children. Here the authors report on a 5-year-old pediatric autologous stem cell recipient, in whom type I membranoproliferative glomerulonephritis developed 111 days after bone marrow transplantation and presented with hematuria, hypertension, proteinuria, and renal failure.
Sakarcan
Abdullah
A
Department of Pediatrics, University of South Carolina School of Medicine, Columbia, SC 29203, USA. abdullahsakarcan@hotmail.com
Neuberg
Ronnie W
RW
McRedmond
Kevin P
KP
Islek
Ismail
I
D002675:Child, Preschool; D015432:Glomerulonephritis, Membranoproliferative / Q000175:diagnosis* / Q000209:etiology*; D006417:Hematuria / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology; D007678:Kidney Glomerulus / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D016253:Microscopy, Immunoelectron / Q000379:methods; D011507:Proteinuria / Q000175:diagnosis / Q000209:etiology; D051437:Renal Insufficiency / Q000175:diagnosis / Q000209:etiology; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D014182:Transplantation, Autologous / Q000009:adverse effects