title: [Laparoscopic transperitoneal replacement of the abdominal aorta with left renal artery reimplantation: experimental study on pigs].
abstract: OBJECTIVE
  To study the feasibility and the tolerance of a combined laparoscopic transperitoneal aortic and renal restoration performed on animals.
  
  
  METHODS
  Six pigs (mean weight: 79.5 kg, range 73-86) underwent laparoscopic replacement of the abdominal aorta using a 6-mm Dacron(R) graft, with direct reimplantation of the left renal artery. The study protocol was approved by the Advisory committee of Animal Ethics. The animal was placed supine on the operative table with a pillow under the lumbar region in order to raise the aortic area. A first midline, 10-mm diameter trocar was placed under direct vision, 5 cm above the pubis and allowed the insufflation of a 12-mm Hg pneumoperitoneum. One 30 degrees optic was used during the intervention. The pig was then tilted to a 30 degrees Trendelenbourg's position and two other 10-mm trocars were introduced 5 cm medially to the right and left antero-superior iliac spines ). Four other 10-mm incisions were necessary for introduction of an intestinal retractor, a suction-irrigation device and two laparoscopic aortic clamps.
  
  
  RESULTS
  The procedure was performed in all animals in a mean operative time of 320 min (292-366), including ): - a time for aortic and renal artery dissection of 104 min (90-120), - a supra-renal aortic clamping time of 221 min (180-276), - a time for confection of proximal and distal aorto-prosthetic anastomosis of respectively 59 min (40-75) and 64 min (50-80), - a time for the left renal artery reimplantation of 72 min (40-140). Average blood loss was 525 ml (250-1050), and the mean pre and postoperative hemoglobin and pH values were 9.9 g/dl (8.9-10.7) versus 9.4 g/dl (8.5-11.3) and 7.36 (7.31-7.38) versus 7.30 (7.21-7.43) respectively. An angiogram ) performed before the sacrifice of animals showed a wide patent anastomosis in 18 (56%) cases, a<50% stenosis in 4 cases (22%), a > 50% stenosis in 1 case (5%) and a thrombosis of the first three renal artery restorations (17%) probably due to insufficient intraoperative heparinization.
  
  
  CONCLUSIONS
  This experimental study shows the feasibility of laparoscopic transperitoneal abdominal aortic restoration with re-implantation of the left renal artery (fig. et ). The techniques of arterial sutures must be improved in order to decrease aortic and renal clamping times.
authors.affiliation: Service de Chirurgie Vasculaire, Centre Hospitalier Universitaire Nord, Marseille, France.
authors.forename: Y S
authors.initials: YS
authors.lastname: Alimi
authors.forename: O
authors.initials: O
authors.lastname: Hartung
authors.forename: T
authors.initials: T
authors.lastname: Lonjon
authors.forename: P
authors.initials: P
authors.lastname: Barthares
authors.forename: L
authors.initials: L
authors.lastname: Cador
authors.forename: C
authors.initials: C
authors.lastname: Juhan
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery*; D016063:Blood Loss, Surgical; D019917:Blood Vessel Prosthesis Implantation; D005240:Feasibility Studies; D010535:Laparoscopy; D008297:Male; D011093:Polyethylene Terephthalates; D011183:Postoperative Complications; D012077:Renal Artery / Q000601:surgery*; D012078:Renal Artery Obstruction / Q000209:etiology; D013552:Swine; D013927:Thrombosis / Q000209:etiology
chemical_list: D011093:Polyethylene Terephthalates