title: Effect of a microaerosol filter on spirometry in children with cystic fibrosis.
abstract: OBJECTIVE
  To measure the effect of an in-line microaerosol filter on spirometric values in cystic fibrosis (CF).
  
  
  METHODS
  Twenty-six subjects with CF undertook a randomized, open, cross-over comparison of spirometry with and without an in-line filter.
  
  
  RESULTS
  The filter had no significant effect on spirometric parameters nor was there any order effect. Measurement error was unrelated to the magnitude of the measurement.
  
  
  CONCLUSIONS
  In-line microaerosol filters do not affect spirometric values or variability in children with CF.
authors.affiliation: Cystic Fibrosis/Respiratory Unit, Department of Child Health, University Hospital of Wales, Cardiff, UK.
authors.forename: D
authors.initials: D
authors.lastname: Rogers
authors.forename: I J M
authors.initials: IJ
authors.lastname: Doull
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D018592:Cross-Over Studies; D003550:Cystic Fibrosis / Q000503:physiopathology*; D005260:Female; D005374:Filtration; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D013147:Spirometry / Q000379:methods*; D014797:Vital Capacity