Cine-MR Fourier phase imaging for quantification of regional wall asynergy in patients with anterior myocardial infarction.
OBJECTIVE
The aim of this study was to evaluate whether Fourier analysis of cine-MR could detect wall motion abnormalities in patients with myocardial infarction.


METHODS
Ten patients with anterior myocardial infarction (seven men and three women; mean age, 58 +/- 16 years) were compared with six control subjects (four men and two women; mean age, 49 +/- 24 years). Gradient echo cardiac cine-MR slices were transformed using a commercially available Fourier algorithm to obtain phase angles of endocardial segments. Mean phase angle and phase dispersion (i.e., SD around the mean) were calculated. Segmental wall motion was evaluated using a 16-segment model and correlated to Fourier phase analysis.


RESULTS
Mean phase angle and phase dispersion were increased in patients compared with control subjects (respectively, 191 degrees +/- 23 degrees vs. 161 degrees +/- 25 degrees, P < 0.0001 and 21 degrees +/- 10 degrees vs. 11 degrees +/- 8 degrees, P = 0.0007). Analysis of variance showed a significant increased dispersion on basal slices (P = 0.002) mostly due to flow-void and entry slice phenomenon.


CONCLUSIONS
Fourier phase analysis of cardiac cine-MR is feasible and allows the evaluation of ventricular asynergy on the basis of endocardial wall motion.
Manrique
Alain
A
Département de Médecine Nucléaire, Centre Henri Becquerel et CHU de Rouen, France. alain.manrique@rouen.fnclc.fr
Tapon
Eric
E
Derumeaux
Geneviève
G
Cribier
Alain
A
Véra
Pierre
P
Dacher
Jean Nicolas
JN
D005260:Female; D005583:Fourier Analysis; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*