Safety and efficacy of cutting balloon angioplasty: the Mayo Clinic experience.
A number of evolving clinical indications for cutting balloon angioplasty (CBA) have been described in the clinical literature, including angioplasty-resistant stenoses, in-stent restenosis, ostial lesions and small vessel disease.


METHODS
We analyzed the Mayo Clinic PTCA registry and report procedural and in-hospital clinical outcomes in 100 patients (103 procedures, 114 lesions) undergoing CBA.


RESULTS
CBA was successfully completed in 109 lesions (96%). The majority of lesions (73%) required additional treatment with either balloon angioplasty (39%) or stent implantation (34%). Severe intimal dissection resulting in at least 50% luminal obstruction occurred in 13 lesions (11%). A single incident of branch occlusion was documented, resulting in ST elevation myocardial infarction. There were no incidents of vessel perforation, urgent percutaneous or surgical target vessel revascularization, or in-hospital death.


CONCLUSIONS
CBA is feasible and safe, with a low incidence of procedural complications and in-hospital adverse cardiac events when used primarily for in-stent restenosis.
Orford
James L
JL
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA.
Fasseas
Panayotis
P
Denktas
Ali E
AE
Hammes
LaVon
L
Garratt
Kirk N
KN
Berger
Peter B
PB
Holmes
David R
DR
Barsness
Gregory W
GW
D000046:Academic Medical Centers; D000368:Aged; D000789:Angina, Unstable / Q000000981:diagnostic imaging / Q000628:therapy*; D000800:Angioplasty, Balloon / Q000295:instrumentation* / Q000379:methods; D017023:Coronary Angiography; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008910:Minnesota; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000628:therapy*; D011379:Prognosis; D012042:Registries; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D015607:Stents; D016896:Treatment Outcome