P-ANCA vasculitic neuropathy with 12-year latency between onset of neuropathy and systemic symptoms.
BACKGROUND
The differential diagnosis of chronic progressive multifocal asymmetric neuropathies is challenging. Vasculitic neuropathies, multifocal forms of chronic inflammatory demyelinating polyneuropathy, multifocal motor neuropathies, and asymmetric lower motor neuron disorders are important considerations.


METHODS
We report a patient with an unusually long 12-year course of nonsystemic vasculitic neuropathy prior to the development of systemic manifestations.


CONCLUSIONS
We discuss some of the difficulties involved in the diagnosis of chronic progressive multifocal asymmetric neuropathies.
Greenberg
Steven A
SA
Division of Neuromuscular Disease, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA. sagreenberg@partners.org
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D002908:Chronic Disease; D003937:Diagnosis, Differential; D018450:Disease Progression; D004576:Electromyography; D006801:Humans; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology; D010146:Pain / Q000209:etiology; D011129:Polyradiculoneuropathy / Q000175:diagnosis* / Q000209:etiology; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis
D019268:Antibodies, Antineutrophil Cytoplasmic