title: Polyphenolic compounds from the leaves of Koelreuteria paniculata Laxm.
abstract: From the fresh leaves of Koelreuteria paniculata Laxm (Sapindaceae), four new compounds, named ethyl p-trigallate (1), 3''-O-galloyl-4'-O-galloyl-4-O-galloyl-gallic acid (2), ethyl p-heptagallate (3) and 3''-galloylquercitrin (4), together with 12 known compounds namely catechin (5), galloylepicatechin (6), isorhamnetin (7), kaempferol-3-O-arabinopyranoside (8), quercetin-3'-O-beta-D-arabinopyranoside (9), quercitrin (10), methyl p-digallate (11), methyl m-digallate (12), p-digalloyl acid (13), m-digalloyl acid (14), hyperin (15) and kaempferol-3-O-alpha-L-rhamnoside (16) were isolated by extensive column chromatographic separation. Their structures were elucidated on the basis of chemical and spectroscopic methods. Compound 9 was not reported previously with pyranoside of arabinose at C-3'. Compounds 4 and 9 possessed the activity for PTK inhibition.
authors.affiliation: National Research Laboratory of Natural and Biomimetic Drugs, Peking University, 100083, Beijing, China. whlin@mail.bjmu.edu.cn
authors.forename: Wen-Han
authors.initials: WH
authors.lastname: Lin
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Deng
authors.forename: Hai-Ming
authors.initials: HM
authors.lastname: Lei
authors.forename: Hong-Zheng
authors.initials: HZ
authors.lastname: Fu
authors.forename: Jun
authors.initials: J
authors.lastname: Li
mesh_terms: D002845:Chromatography; D005419:Flavonoids; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D011108:Polymers / Q000737:chemistry* / Q000302:isolation & purification; D059808:Polyphenols; D029631:Sapindaceae / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D005419:Flavonoids; D010636:Phenols; D011108:Polymers; D059808:Polyphenols