title: Tetralogy of Fallot, imperforate anus, and Müllerian, renal, and cervical spine (MURCS) anomalies in a 15-year-old girl.
abstract: OBJECTIVE
  To examine the etiology of MURCs anomalies and the management of a patient with these anomalies as well as cardiac and anorectal abnormalities causing primary amenorrhea and abdominal pain.
  
  
  METHODS
  Case study.
  
  
  RESULTS
  Relief of pelvic pain following GnRH agonist therapy and continuous oral contraceptives.
  
  
  CONCLUSIONS
  MURCS (Müllerian, Renal, Cervical Spine) is a well-described grouping of multi-organ, nonlethal abnormalities that are infrequently detected in women with menstrual abnormalities. The association of MURCS with cardiac and anorectal abnormalities may be one of coincidence or may indicate that the abnormalities share common genetic or environmental (cellular or microbiologic) etiologies.
authors.affiliation: Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL 60612, USA. mgilli2@uic.edu
authors.forename: Melissa
authors.initials: M
authors.lastname: L Gilliam
authors.forename: Lee P
authors.initials: LP
authors.lastname: Shulman
mesh_terms: D000015:Abnormalities, Multiple / Q000628:therapy*; D000293:Adolescent; D000568:Amenorrhea / Q000209:etiology; D001006:Anus, Imperforate / Q000150:complications*; D002574:Cervical Vertebrae / Q000002:abnormalities*; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D009095:Mullerian Ducts / Q000002:abnormalities*; D013577:Syndrome; D013771:Tetralogy of Fallot / Q000150:complications*