title: The spectrum of computerized tomography (CT) findings in central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii in immunocompetent children.
abstract: Cranial CT scans of eleven immunocompetent children with central nervous system (CNS) infection due to Cryptococcus neoformans var. gattii were retrospectively reviewed. These children had an average age of 8.8 years and positive culture for C. n. var. gattii in cerebrospinal fluid. The most common signs and symptoms were headache, fever, nuchal rigidity, nausea and vomiting. No normal cranial CT was detected in any patient. Hypodense nodules were observed in all patients. The remaining scan abnormalities were as follows: nine had diffuse atrophy, six had hydrocephalus, and five had hydrocephalus coexistent with diffuse atrophy.
authors.affiliation: Núcleo de Medicina Tropical, Universidade Federal do Pará, PA, Brasil.
authors.forename: Maria do Perpétuo Socorro Costa
authors.initials: Mdo P
authors.lastname: Correa
authors.forename: Luiz Carlos
authors.initials: LC
authors.lastname: Severo
authors.forename: Flávio de Mattos
authors.initials: Fde M
authors.lastname: Oliveira
authors.forename: Klaus
authors.initials: K
authors.lastname: Irion
authors.forename: Alberto Thomaz
authors.initials: AT
authors.lastname: Londero
mesh_terms: D001927:Brain Diseases / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging* / Q000382:microbiology; D020314:Central Nervous System Fungal Infections / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging* / Q000382:microbiology; D002648:Child; D003453:Cryptococcosis / Q000134:cerebrospinal fluid / Q000532:radiotherapy*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed