title: [Assessment of irregular uterine bleeding in premenopausal women].
abstract: The aim of the present study was to investigate by diagnostic curettage the endometrial histological findings in women with irregular uterine bleeding in premenopause.
  
  
  METHODS
  Two hundred and thirty women between 40 to 54 wears (mean 48.13) with history of irregular genital bleeding in premenopause were investigated. The classic dilatation and curettage of endometrial cavity was performed and histological results were analyzed.
  
  
  CONCLUSIONS
  The histological examination of the curettage material shows--normal endometrium in 32 (13.9%) women, anovulatory endometrium in 59 (26.6%), cystic hyperplasia and/or polyposis in 91 (39.6%), atrophic endometrium in 20 (8.7%), atypical hyperplasia in 15 (6.5%), endometrial cancer in 7 (3.1%) women and without adequate material were 6 (2.6%) cases.
  
  
  CONCLUSIONS
  This study pointed out, that women with irregular uterine bleeding in premenopause still remain serious diagnostic and therapeutic problem. Nevertheless, the separate curettage keeps its important role in assessment of health status of these women.
authors.forename: V
authors.initials: V
authors.lastname: Zlatkov
authors.forename: V
authors.initials: V
authors.lastname: Radeva
authors.forename: G
authors.initials: G
authors.lastname: Cholakova
authors.forename: A
authors.initials: A
authors.lastname: Mikhova
authors.forename: G
authors.initials: G
authors.lastname: Bŭrzakov
authors.forename: E
authors.initials: E
authors.lastname: Velinov
authors.forename: N
authors.initials: N
authors.lastname: Nikolov
mesh_terms: D000328:Adult; D004717:Endometrium / Q000473:pathology; D005260:Female; D006652:Histological Techniques; D006801:Humans; D008875:Middle Aged; D017697:Premenopause; D014592:Uterine Hemorrhage / Q000473:pathology*