title: True multifood allergy in a 4-year-old child: a case study.
abstract: BACKGROUND
  Food allergy is quite common in children, but it usually trends to improve with ageing. When an individual has specific IgE to a large variety of foods (multifood allergy) the clinical picture may be of remarkable severity and the avoidance of the offending foods may lead to severe dietary impairment. We describe a case of a child with ascertained multifood allergy.
  
  
  METHODS
  The prick-by-prick testing with fresh foods and serum IgE tests were used to evaluate the patient's sensitivity to food allergens. The clinical effect of sensitizations were evaluated by DBPCFC which was carried out for egg, fish, peanuts, walnut, fig, asparagus, orange, chicory, medlar, peach, strawberry and cherry. Each challenge was performed on a separate day. Medical assistance and resuscitation facilities were available during the whole challenge procedures.
  
  
  RESULTS
  SPT with fresh food gave a 4 mm wheal for fig, asparagus, cherry and walnut; a 5 mm wheal for medlar and orange; a 6 mm wheal for chicory and strawberry; a 7 mm wheal for fish and peanuts; an 8 mm wheal for peach and a 9 mm wheal for egg. The RAST assay confirmed the presence of specific IgE to egg, fish, peanuts, walnut, fig, orange, strawberry, peach, and cherry. The total serum IgE was 730,6 kU/l.The DBPCFC was positive, at various degrees, for all foods tested according to skin sensitizations.
  
  
  CONCLUSIONS
  The case herein described is a true multifood allergy, as confirmed by the DBPCFC. Multifood allergy is not common, but when present it can lead to severe dietary limitation.
authors.affiliation: II Pediatric Division. University Hospital. Messina. Italy. Giovanni.Pajno@unime.it
authors.forename: G B
authors.initials: GB
authors.lastname: Pajno
authors.forename: G
authors.initials: G
authors.lastname: Passalacqua
authors.forename: S
authors.initials: S
authors.lastname: La Grutta
authors.forename: D
authors.initials: D
authors.lastname: Vita
authors.forename: R
authors.initials: R
authors.lastname: Feliciotto
authors.forename: S
authors.initials: S
authors.lastname: Parmiani
authors.forename: G
authors.initials: G
authors.lastname: Barberio
mesh_terms: D000485:Allergens; D000818:Animals; D000918:Antibody Specificity; D010367:Arachis / Q000009:adverse effects / Q000276:immunology; D001249:Asthma / Q000209:etiology; D002675:Child, Preschool; D004531:Eggs / Q000009:adverse effects; D005399:Fishes / Q000276:immunology; D005512:Food Hypersensitivity / Q000209:etiology*; D005638:Fruit / Q000009:adverse effects / Q000276:immunology; D005759:Gastroenteritis / Q000209:etiology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology*; D008297:Male; D009754:Nuts / Q000009:adverse effects / Q000276:immunology; D017747:Seafood / Q000009:adverse effects; D012882:Skin Tests; D014581:Urticaria / Q000209:etiology; D014675:Vegetables / Q000009:adverse effects / Q000276:immunology
chemical_list: D000485:Allergens; D007073:Immunoglobulin E