title: Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China.
abstract: We examined risk factors associated with Necator americanus infection among persons aged > or =50 years in Hainan Province, People's Republic of China. Age and sex made the most important contributions to the variation in infection intensity (28%-30%), with age alone responsible for 27% of this variation. When stratified by 20-year age intervals, the influence of shared residence was 23% for persons aged > or =50 years and 27% for those aged <20 years, who had the highest and lowest levels of infection intensity, respectively. This points to shared residence as a means of capturing the complex relationship between aging and shared socioeconomic, environmental, and behavioral factors that influence transmission of Necator infection. None of the other 26 personal or 32 household risk factors were found to be significant. The importance of aging in Necator infection reveals an emerging public health problem among the elderly population of developing countries.
authors.affiliation: George Washington University, Washington, DC, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Bethony
authors.forename: Jizhang
authors.initials: J
authors.lastname: Chen
authors.forename: Shaoxiong
authors.initials: S
authors.lastname: Lin
authors.forename: Shuhua
authors.initials: S
authors.lastname: Xiao
authors.forename: Bin
authors.initials: B
authors.lastname: Zhan
authors.forename: Shangwen
authors.initials: S
authors.lastname: Li
authors.forename: Haichou
authors.initials: H
authors.lastname: Xue
authors.forename: Fuying
authors.initials: F
authors.lastname: Xing
authors.forename: Debbie
authors.initials: D
authors.lastname: Humphries
authors.forename: Wang
authors.initials: W
authors.lastname: Yan
authors.forename: Grace
authors.initials: G
authors.lastname: Chen
authors.forename: Virginia
authors.initials: V
authors.lastname: Foster
authors.forename: John M
authors.initials: JM
authors.lastname: Hawdon
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Hotez
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000818:Animals; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017221:Necator americanus; D009332:Necatoriasis / Q000453:epidemiology / Q000503:physiopathology*; D012307:Risk Factors; D012737:Sex Factors