title: Symptomatic epidural lipomatosis of the spinal cord in a child: MR demonstration of spinal cord injury.
abstract: We report a case of symptomatic epidural lipomatosis in an 8-year-old girl with Cushing's syndrome secondary to longstanding high-dose steroid therapy for Crohn's disease. MR imaging of the spine revealed massive diffuse epidural fat compressing the entire spinal cord with T2 prolongation in the central gray matter of the cord suggesting ischemic myelopathy. This finding has not been previously demonstrated on imaging. A proposed mechanism underlying these findings is discussed.
authors.affiliation: Department of Radiology, Section of Neuroradiology, University of California-San Francisco, CA 94143-0638, USA. almugo@teleline.es
authors.forename: Alberto
authors.initials: A
authors.lastname: Muñoz
authors.forename: James A
authors.initials: JA
authors.lastname: Barkovich
authors.forename: Fernando
authors.initials: F
authors.lastname: Mateos
authors.forename: Rogelio
authors.initials: R
authors.lastname: Simón
mesh_terms: D002648:Child; D003424:Crohn Disease / Q000150:complications; D003480:Cushing Syndrome / Q000150:complications; D003937:Diagnosis, Differential; D004824:Epidural Space; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008068:Lipomatosis / Q000175:diagnosis* / Q000209:etiology; D008279:Magnetic Resonance Imaging; D013117:Spinal Cord Compression / Q000175:diagnosis* / Q000209:etiology