title: Reactivation of a Trypanosoma cruzi infection in a rhesus monkey (Macaca mulatta) experimentally infected with SIV.
abstract: Trypanosoma cruzi-like flagellates were incidentally noted in blood smears of a routinely monitored rhesus monkey experimentally infected with the simian immunodeficiency virus (SIV). Immunodeficiency in the course of the SIV infection reactivated a chronic infection of Chagas' disease that had been unnoticed when the macaque was imported to Europe. The animal developed no specific clinical symptoms of American trypanosomiasis, but histologically a chagasic myocarditis was detected. Analysis of the small subunit rRNA gene of the trypanosome identified the protozoan as T. cruzi.
authors.affiliation: Department of Primate Veterinary Medicine and Primate Husbandry, German Primate Center, 37077 Göttingen, Germany. emanuela.kunz@ze.uni-ulm.de
authors.forename: E
authors.initials: E
authors.lastname: Kunz
authors.forename: K
authors.initials: K
authors.lastname: Mätz-Rensing
authors.forename: N
authors.initials: N
authors.lastname: Stolte
authors.forename: P B
authors.initials: PB
authors.lastname: Hamilton
authors.forename: F J
authors.initials: FJ
authors.lastname: Kaup
mesh_terms: D000818:Animals; D002598:Chagas Cardiomyopathy / Q000473:pathology / Q000662:veterinary / Q000821:virology; D014355:Chagas Disease / Q000150:complications / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D008253:Macaca mulatta; D008297:Male; D008992:Monkey Diseases / Q000469:parasitology* / Q000473:pathology / Q000821:virology*; D016097:Simian Acquired Immunodeficiency Syndrome / Q000469:parasitology* / Q000821:virology; D015302:Simian Immunodeficiency Virus / Q000254:growth & development*; D014349:Trypanosoma cruzi / Q000254:growth & development*