Resistance to macrolides in Group A streptococci from the European section of Turkey: genetic and phenotypic characterization.
The aim of this study was to determine the susceptibilities to macrolides of Group A streptococcal isolates from the European section of Turkey. In the case of resistant isolates, the patterns and genetic mechanisms of erythromycin resistance were studied. Seven (2.7%) of the 260 isolates were resistant to erythromycin. Four of them showed the M phenotype and harboured mefA genes whereas three isolates showed the inducible macrolide, lincosamide and streptogramin B resistance phenotype and harboured ermTR genes. In the European section of Turkey, the current resistance rate of Group A streptococci to macrolides remains low.
Akata
Filiz
F
Department of Clinical Bacteriology and Infectious Diseases, Medical Faculty of Trakya University, 22030 Edirne, Turkey. mikro@trakya.edu.tr
Oztürk
Devrim
D
Tansel
Ozlem
O
Tatman-Otkun
Müserref
M
Otkun
Metin
M
Fitoussi
Frederic
F
Bingen
Edouard
E
Tugrul
Murat
M
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004917:Erythromycin / Q000494:pharmacology*; D005060:Europe / Q000208:ethnology; D006801:Humans; D008826:Microbial Sensitivity Tests; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000187:drug effects* / Q000235:genetics*; D014421:Turkey
D000900:Anti-Bacterial Agents; D004917:Erythromycin