Fine-needle aspiration cytology of extranodal natural killer/T-cell lymphoma.
Extranodal NK/T-cell lymphoma, nasal type, is a predominantly extranodal lymphoma characterized histologically by prominent necrosis, angiocentric growth, and vascular destruction. Only one report describing its fine-needle aspiration (FNA) cytologic features is available and shows highly unusual findings for a lymphoma. The present case concerns a 58-yr-old patient that presented with a soft tissue mass of the thigh in addition to an ulcerative lesion of the palate and nodular hepatic and splenic lesions. FNA cytology of the thigh tumor was interpreted as a malignant mesenchymal lesion (sarcoma). The subsequent pathologic study revealed an NK/T-cell lymphoma. Our findings are very similar to those previously reported. They were highly unusual for a lymphoma and consisted of polymorphic, round to spindle neoplastic cells distributed in irregular aggregates, and single cells. No significant number of lymphoglandular bodies were present.
Jiménez-Heffernan
José A
JA
Department of Pathology, University Hospital, Guadalajara, University of Alcalá de Henares, Madrid, Spain. jjheffernan@yahoo.com
González-Peramato
Pilar
P
Perna
Cristian
C
Alvarez-Ferreira
Javier
J
López-Ferrer
Pilar
P
Viguer
José M
JM
D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology*; D016131:Lymphocyte Subsets / Q000473:pathology*; D016411:Lymphoma, T-Cell, Peripheral / Q000473:pathology*; D008297:Male; D012509:Sarcoma / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000473:pathology*