Association between flupenthixol treatment and emergence of manic symptoms.
BACKGROUND
Flupenthixol is an antipsychotic drug with known mood-elevating properties. Its propensity to induce manic symptoms has not been investigated.


RESULTS
We describe six patients, four with schizophrenia and two with bipolar disorder, in whom flupenthixol treatment was associated with emergence of manic symptoms.


CONCLUSIONS
Patients treated with flupenthixol should be carefully monitored for the emergence of manic symptoms.
Becker
D
D
Ness-Ziona Mental Health Center, Ness-Ziona, P.O. Box 1, Ness-Ziona 74450, Israel.
Grinberg
Y
Y
Weizman
A
A
Mester
R
R
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000175:diagnosis; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005475:Flupenthixol / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy*
D014150:Antipsychotic Agents; D005475:Flupenthixol