Synthesis of aglycon analogues of sarmentosin and their bioactivity of lymphocyte proliferation.
A number of aglycon analogues of sarmentosin were prepared and their bioactivities on the proliferation of T-lymphocytes and B-lymphocytes were assayed.
Zhang
Hong
H
Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 294 Tai-yuan Road, China.
Xu
Rui
R
Hu
Zhongliang
Z
He
Xuchang
X
Bai
Donglu
D
Li
Xiaoyu
X
Wang
Xiaofeng
X
D000818:Animals; D001402:B-Lymphocytes / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D005947:Glucose / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D006841:Hydrocarbons, Aromatic; D008213:Lymphocyte Activation / Q000187:drug effects*; D051379:Mice; D008813:Mice, Inbred ICR; D009570:Nitriles / Q000138:chemical synthesis* / Q000494:pharmacology; D010936:Plant Extracts / Q000138:chemical synthesis / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013601:T-Lymphocytes / Q000187:drug effects
D006841:Hydrocarbons, Aromatic; D009570:Nitriles; D010936:Plant Extracts; C082842:sarmentosine; D005947:Glucose