title: Multiple eccrine spiradenomas on the hand, forearm and head.
abstract: The first case of multifocal eccrine spiradenomas on the hand, forearm and scalp is described. This case is unusual in that the tumors located on the little finger included the nail matrix and occurred in a linear/zosteriform distribution, resulting in a nail deformity. The nodules on the forearm and scalp were in a random distribution. Histologically, each tumor was highly cellular and composed of two cell types: small darkly staining basaloid cells and larger, pale cells. Ultrastructural observations often showed an intracellular lumen with numerous microvilli in larger pale-staining cells.
authors.affiliation: Surgical Division (Section of Plastic and Reconstructive Surgery), Ehime University Hospital, Ehime, Japan. ohsuka@m.ehime-u.ac.jp
authors.forename: Hisashi
authors.initials: H
authors.lastname: Ohtsuka
authors.forename: Kei
authors.initials: K
authors.lastname: Tezuka
authors.forename: Masanobu
authors.initials: M
authors.lastname: Kumakiri
authors.forename: Yuji
authors.initials: Y
authors.lastname: Ohtsuki
mesh_terms: D006607:Adenoma, Sweat Gland / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D005542:Forearm; D006225:Hand; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D008875:Middle Aged; D018570:Risk Assessment; D012535:Scalp; D012867:Skin / Q000648:ultrastructure; D013544:Sweat Gland Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery