title: Andirol A and B, two unique 6-hydroxymethylpterocarpenes from Andira inermis.
abstract: From a methanolic extract of the leaves of Andira inermis (Fabaceae), andirol A and B, two compounds with a novel type of a rotenoid-related skeleton and andinermol, a new 2-aryl-3-hydroxymethyl-benzofuran could be isolated. Characterisation and structure elucidation of these compounds was achieved on the basis of their spectral data. In addition, the in vitro activities of the isolated compounds against both the chloroquine-sensitive strain PoW and the chloroquine-resistant clone Dd2 of Plasmodium falciparum have been evaluated.
authors.affiliation: Institut für Pharmazie (Pharmazeutische Biologie), Freie Universität Berlin, Gremany.
authors.forename: Carola
authors.initials: C
authors.lastname: Kraft
authors.forename: Kristina
authors.initials: K
authors.lastname: Jenett-Siems
authors.forename: Inga
authors.initials: I
authors.lastname: Köhler
authors.forename: Karsten
authors.initials: K
authors.lastname: Siems
authors.forename: Daniel
authors.initials: D
authors.lastname: Abbiw
authors.forename: Ulrich
authors.initials: U
authors.lastname: Bienzle
authors.forename: Eckart
authors.initials: E
authors.lastname: Eich
mesh_terms: D000447:Aldehydes / Q000737:chemistry / Q000302:isolation & purification; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification; D007887:Fabaceae / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D000432:Methanol; D008958:Models, Molecular; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000447:Aldehydes; D001572:Benzofurans; D006576:Heterocyclic Compounds, 4 or More Rings; D010936:Plant Extracts; C448099:andinermal; C469686:andirol A; C469687:andirol B; D000432:Methanol