title: Current status of estrogen receptors.
abstract: Increasing knowledge on structure and function of estrogen receptors is providing information on the mechanism of action of estrogen agonists, as well as antagonists, and in understanding their tissue-selective action. However, there are still many factors associated with estrogen response which are poorly understood. Therefore, the task of designing a tissue-selective estrogen for use as a pharmaceutical in estrogen-dependent disorders remains an uncertain game. This review provides information on the current status of estrogen receptors for a better understanding.
authors.affiliation: Medicinal Chemistry Division, Central Drug Research Institute, Lucknow 226001, India. sraycdri@yahoo.com
authors.forename: Suprabhat
authors.initials: S
authors.lastname: Ray
authors.forename: Reema
authors.initials: R
authors.lastname: Rastogi
authors.forename: Atul
authors.initials: A
authors.lastname: Kumar
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods; D004965:Estrogen Antagonists / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy / Q000379:methods; D006801:Humans; D011960:Receptors, Estrogen / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000145:classification / Q000378:metabolism*
chemical_list: D004965:Estrogen Antagonists; D011960:Receptors, Estrogen