title: Acute haemorrhagic oedema of infancy associated with cytomegalovirus infection.
abstract: Acute haemorrhagic oedema (AHO) of infancy is a cutaneous leukocytoclastic vasculitis, clinically characterized by the acute development of peripheral oedema and targetoid purpuric lesions on the face and extremities. It usually affects children younger than 2 years of age. The disorder follows a benign course usually without recurrence or long-term complication. In most cases the origin is not clear, but underlying infections are assumed to play an aetiological role. We describe a 7-month-old boy whose clinical and histopathological features are typical of AHO. Serological tests clearly demonstrated a primary infection for cytomegalovirus (CMV). To our knowledge, this is the first reported case of AHO associated with CMV infection.
authors.affiliation: Department of Dermatology, Shimotsuga General Hospital, 5-32 Fujimi-cho, Tochigi 328-8505, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kuroda
authors.forename: H
authors.initials: H
authors.lastname: Yabunami
authors.forename: Y
authors.initials: Y
authors.lastname: Hisanaga
mesh_terms: D000208:Acute Disease; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000473:pathology; D004487:Edema / Q000473:pathology / Q000821:virology; D006801:Humans; D007223:Infant; D008297:Male; D017445:Skin Diseases, Vascular / Q000473:pathology / Q000821:virology*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000473:pathology / Q000821:virology*