title: Improvement of acquired pendular nystagmus by gabapentin: case report.
abstract: Acquired Pendular Nystagmus (APN) may cause distressing visual symptoms in patients who are already suffering a severe general disease. Averbuch-Heller et al. conducted the first double-blind controlled study on treatment for APN. They showed that gabapentin substantially reduces pendular nystagmus and significantly increases visual acuity in the majority of patients. We present a patient with APN due to multiple sclerosis who suffered severe oscillopsy and reduction of visual acuity and who substantially benefited from a trial treatment with this agent.
authors.affiliation: Dienst Oogheelkunde, A.Z. Middelheim, Antwerpen.
authors.forename: K
authors.initials: K
authors.lastname: Fabre
authors.forename: H
authors.initials: H
authors.lastname: Smet-Dieleman
authors.forename: T
authors.initials: T
authors.lastname: Zeyen
mesh_terms: D000085:Acetates / Q000627:therapeutic use*; D000284:Administration, Oral; D000588:Amines; D001418:Baclofen / Q000008:administration & dosage; D003509:Cyclohexanecarboxylic Acids; D005260:Female; D000077206:Gabapentin; D006801:Humans; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D009759:Nystagmus, Pathologic / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome; D005680:gamma-Aminobutyric Acid
chemical_list: D000085:Acetates; D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin; D001418:Baclofen