Structural abnormalities and changes in Na,K-ATPase activity in erythrocyte membranes in patients with neurotic disorders.
We studied structural and metabolic characteristics of erythrocyte membranes in 19 patients with neurotic disorders (neurasthenia and dysadaptation). Microviscosity of the lipid phase in erythrocyte membranes increased in 13 patients, and Na,K-ATPase activity decreased in 6 patients. Various changes in test parameters are probably associated with different adaptive capacities of the organism under stress conditions.
Ryazantseva
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NV
Siberian State Medical University, Russian Ministry of Health. ryazan@mail.tomsknet.ru
Novitskii
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VV
D000328:Adult; D002462:Cell Membrane / Q000201:enzymology* / Q000378:metabolism; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005456:Fluorescent Dyes / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009440:Neurasthenia / Q000097:blood* / Q000201:enzymology; D009497:Neurotic Disorders / Q000201:enzymology*; D011721:Pyrenes / Q000494:pharmacology; D000254:Sodium-Potassium-Exchanging ATPase / Q000737:chemistry* / Q000378:metabolism; D013312:Stress, Physiological
D005456:Fluorescent Dyes; D011721:Pyrenes; C030984:pyrene; D000254:Sodium-Potassium-Exchanging ATPase