[Inhibiting effect of intrathecal fentanyl on intraoperative vomiting during cesarean delivery under epidural anesthesia].
OBJECTIVE
To observe the inhibiting effect of intrathecal (IT) fentanyl on nausea and vomiting during cesarean delivery under epidural anesthesia.


METHODS
Thirty healthy parturients (ASA grade I to II) were randomly assigned in equal numbers into control and fentanyl groups (n=15 each, patients in the latter group treated with IT fentanyl at the dose of 20 microgram/3ml). The incidence of nausea and vomiting during the elective cesarean delivery under epidural anesthesia between the 2 groups were compared and the neonates' Apgar scores assessed after the delivery.


RESULTS
Intraoperative nausea and vomiting/retching were reduced in the IT fentanyl group as compared with the control group (6.7 % vs 33.3 % and 0 vs 26.7 %, P>0.05 and P<0.05 respectively). The neonates' Apgar scores were not significantly different between the 2 groups (P>0.05).


CONCLUSIONS
IT fentanyl can decrease intraoperative vomiting during cesarean delivery performed under epidural anesthesia.
Ouyang
Ming-Wen
MW
Department of Anesthesia, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Gu
Miao-Ning
MN
Lin
Chun-Shui
CS
D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D000767:Anesthesia, Epidural / Q000009:adverse effects*; D002585:Cesarean Section / Q000009:adverse effects*; D005260:Female; D005283:Fentanyl / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D007278:Injections, Spinal; D007430:Intraoperative Care; D007431:Intraoperative Complications / Q000188:drug therapy*; D014839:Vomiting / Q000188:drug therapy* / Q000453:epidemiology
D000701:Analgesics, Opioid; D005283:Fentanyl