title: Clinical features and treatment prognosis of infertile males with robertsonian translocation.
abstract: BACKGROUND
  The principle of treating male infertility in those with chromosomal aberrations should change according to progress in treatment modalities.
  
  
  METHODS
  In this study, ten patients with Robertsonian translocation were assessed for their cytogenetic and clinical characteristics to establish guidelines for treating these patients.
  
  
  RESULTS
  In 8 of 10 cases, chromosomes 13 and 14 were involved. In 4 of 10 cases (40%), their wives became pregnant, including two spontaneously. All newborns were without any deformities including one boy who was shown to have a normal karyotype.
  
  
  CONCLUSIONS
  Infertility treatment of patients with Robertsonian translocation should be optimistically performed on the basis of proper informed consent.
authors.affiliation: Department of Urology, Osaka Central Hospital, Osaka University Medical School, Osaka, Japan. urokon@hyo-med.ac.jp
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Kondoh
authors.forename: Kiyomi
authors.initials: K
authors.lastname: Matsumiya
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Minoru
authors.initials: M
authors.lastname: Koga
authors.forename: Kenji
authors.initials: K
authors.lastname: Nishimura
authors.forename: Masaya
authors.initials: M
authors.lastname: Kitamura
authors.forename: Masami
authors.initials: M
authors.lastname: Takeyama
authors.forename: Akihiko
authors.initials: A
authors.lastname: Okuyama
mesh_terms: D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D014178:Translocation, Genetic