Effects of horseradish root on functional activity of phagocytes, total blood cell count, and state of the liver in mice with experimental leprosy.
Therapy of experimental leprosy with dried and grated horseradish root administered perorally in a dose of 300 mg/kg mixed food and treatment with purified horseradish peroxidase increased myeloperoxidase activity of blood neutrophils, enhanced antimicrobial functions of phagocytes, decreased leukocytosis, normalized total blood cell count, and produced no adverse effects on the functional state of the liver in mice.
Maslov
A K
AK
Institute for Leprosy, Russian Ministry of Health, Astrakhan.
Luzhnova
S A
SA
Kalyanina
O V
OV
D000818:Animals; D031215:Armoracia / Q000737:chemistry*; D001772:Blood Cell Count; D004305:Dose-Response Relationship, Drug; D007918:Leprosy / Q000276:immunology* / Q000503:physiopathology; D008099:Liver / Q000187:drug effects* / Q000276:immunology / Q000503:physiopathology; D051379:Mice; D008808:Mice, Inbred CBA; D010586:Phagocytes / Q000187:drug effects* / Q000276:immunology; D018517:Plant Roots / Q000737:chemistry*