title: Influence of irrigants on the coronal microleakage of laterally condensed gutta-percha root fillings.
abstract: OBJECTIVE
  To assess in vitro coronal microleakage in extracted human teeth after root-canal treatment, using different endodontic irrigants.
  
  
  METHODS
  Fifty teeth with single root canals were prepared and filled using the lateral condensation of gutta-percha and Endométhasone sealer. Canal preparation consisted of initial shaping of the coronal two-thirds with Gates-Glidden burs size 2 and 3, followed by preparation of the apical stop and step-back flaring with manual files. Each group (n = 10) was irrigated with the following solutions: I--1% NaOCl, II--1% NaOCl + 17% EDTA, III--2% chlorhexidine gel, IV--2% chlorhexidine gel + 1% NaOCl, and V--distilled water. After root-canal filling, the teeth were incubated at 37 degrees C for 10 days followed by 10 days immersion in human saliva and an additional 10 days in India ink. The teeth were cleared and maximum dye penetration was determined digitally in millimetres. Statistical analysis was carried out using the Kruskal-Wallis test.
  
  
  RESULTS
  Least leakage occurred with 1% NaOCl + 17% EDTA (2.62 mm) and 2% chlorhexidine gel (2.78 mm) (P > 0.05). NaOCl (3.51 mm), distilled water (6.10 mm) and 2% chlorhexidine gel + 1% NaOCl (9.36 mm) gave increased leakage with a significant difference compared to NaOCl + 17% EDTA and 2% chlorhexidine gel, and compared to one another (P < 0.05).
  
  
  CONCLUSIONS
  Under the condition of this study, irrigation method during root-canal treatment influenced coronal microleakage. NaOCl + EDTA and chlorhexidine gel allowed better sealing following root filling.
authors.affiliation: School of Dentistry of Piracicaba, University of Campinas, Avenue Limeira, 901, Piracicaba-SP, CEP-13414-018, Brazil.
authors.forename: N
authors.initials: N
authors.lastname: Vivacqua-Gomes
authors.forename: C C R
authors.initials: CC
authors.lastname: Ferraz
authors.forename: B P F A
authors.initials: BP
authors.lastname: Gomes
authors.forename: A A
authors.initials: AA
authors.lastname: Zaia
authors.forename: F B
authors.initials: FB
authors.lastname: Teixeira
authors.forename: F J
authors.initials: FJ
authors.lastname: Souza-Filho
mesh_terms: D000287:Administration, Topical; D000891:Anti-Infective Agents, Local / Q000737:chemistry; D000893:Anti-Inflammatory Agents / Q000737:chemistry; D002244:Carbon; D002614:Chelating Agents / Q000737:chemistry; D002710:Chlorhexidine / Q000737:chemistry; D004396:Coloring Agents; D001840:Dental Bonding; D003763:Dental Leakage / Q000145:classification*; D003907:Dexamethasone / Q000737:chemistry; D004202:Disinfectants / Q000737:chemistry; D004338:Drug Combinations; D004492:Edetic Acid / Q000737:chemistry; D005557:Formaldehyde / Q000737:chemistry; D006171:Gutta-Percha / Q000737:chemistry*; D006801:Humans; D006854:Hydrocortisone; D007091:Image Processing, Computer-Assisted; D012387:Root Canal Filling Materials / Q000737:chemistry*; D012388:Root Canal Irrigants / Q000737:chemistry*; D018915:Root Canal Preparation / Q000295:instrumentation / Q000379:methods; D012463:Saliva / Q000737:chemistry; D012973:Sodium Hypochlorite / Q000737:chemistry; D018709:Statistics, Nonparametric; D013696:Temperature; D013943:Thymol / Q000031:analogs & derivatives* / Q000737:chemistry; D013997:Time Factors
chemical_list: D000891:Anti-Infective Agents, Local; D000893:Anti-Inflammatory Agents; D002614:Chelating Agents; D004396:Coloring Agents; D004202:Disinfectants; D004338:Drug Combinations; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; C028433:chinese ink; C011244:corticosteroid methanetriol mixture; D005557:Formaldehyde; D013943:Thymol; D002244:Carbon; D003907:Dexamethasone; D006171:Gutta-Percha; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D002710:Chlorhexidine; D006854:Hydrocortisone