title: Peyronie's disease: surgical management: autologous materials.
abstract: Peyronie's disease in men with satisfactory erectile function but with significant penile curvature is often treated with plaque incision or excision and grafting. The advantages and disadvantages of various grafting materials have long been debated. While artificial materials have been used, the inflammatory reaction from these grafts has produced poor results. Dermal, venous and tunica vaginalis grafts require additional operative time to harvest and their quality varies. Packaged grafts of autologous materials provide a readily available, reliable and well-tolerated choice for penile reconstruction for Peyronie's disease. These grafting materials including cadavaric pericardium, mammalian intestinal serosal products and others are easily obtained and provide a resilient yet compliant graft choice that is easy to tailor and suture in place. Host reaction is minimal and the infection risk small. Results of Peyronie's plaque incision/excision and autologous grafting are presented and the surgical procedures employed are outlined. Excellent results can be expected in the hands of the experienced reconstructive surgeon.
authors.affiliation: Division of Urology, University of North Carolina, Chapel Hill, North Carolina, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Carson
authors.forename: J L
authors.initials: JL
authors.lastname: Chun
mesh_terms: D002102:Cadaver; D006801:Humans; D008297:Male; D010411:Penile Induration / Q000601:surgery*; D010496:Pericardium / Q000637:transplantation; D016378:Tissue Transplantation; D014182:Transplantation, Autologous; D013521:Urologic Surgical Procedures, Male