Effects of Brugia pahangi infection on the cardiovascular system of stroke-prone spontaneously hypertensive rats.
To determine if filarial infection causes any effect on the cardiovascular system of the host animal, stroke-prone spontaneously hypertensive rats were infected with Brugia pahangi under the assumption that these rats would reveal pathological changes more clearly and in a shorter period than would ordinary rats. The infection resulted in loss of body weight, increase in heart weight, enlargement of left ventricle, and higher mortality rate.
Kimura
E
E
Department of Parasitology, Aichi Medical University, Nagakute, Japan. kimura@aichi-med-u.ac.jp
Fujimaki
Y
Y
Niwat
M
M
Fujiwara
M
M
Kadosaka
T
T
D000818:Animals; D001835:Body Weight / Q000502:physiology; D017179:Brugia pahangi / Q000254:growth & development*; D002318:Cardiovascular Diseases / Q000469:parasitology* / Q000473:pathology; D005368:Filariasis / Q000469:parasitology / Q000473:pathology*; D006352:Heart Ventricles / Q000469:parasitology / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000473:pathology*; D009929:Organ Size / Q000502:physiology; D051381:Rats; D011918:Rats, Inbred SHR; D018709:Statistics, Nonparametric