title: [Increased frequency of traffic accidents among patients with disseminated sclerosis].
abstract: BACKGROUND
  The influence of medical conditions on the ability to drive safely is a matter of concern to both physicians and society. Obviously, the symptoms in multiple sclerosis (MS) are of relevance when driving a car. Nevertheless this problem has never before been subject to scientific investigations.
  
  
  METHODS
  A 10-year historical cohort register study on 197 patients with MS and 545 controls individually matched for age, gender, place of residence, and period of exposure. Persons with other neurological diseases, diabetes, or abuse were excluded. The outcome measure was treatment at an emergency department after an accident as a car driver.
  
  
  RESULTS
  Five patients and four controls had been treated. The rate per 1,000 person-years with exposure was 3.4 times higher (CI 0.73-17.15) in the patients than in the control cohort. The difference is significant in a one-sided test (p = 0.04).
  
  
  CONCLUSIONS
  This study showed that drivers with MS were more often treated at a casualty department after having a road traffic accident than healthy controls. In view of the small numbers, the results should be interpreted cautiously, and no drastic measures should be taken regarding patients' driving until the results have been further substantiated.
authors.affiliation: Arbejds- og miljømedicinsk klinik, Odense Universitetshospital, DK-5000 Odense C. s.lings@ouh.fyns-amt.dk
authors.forename: Svend
authors.initials: S
authors.lastname: Lings
mesh_terms: D000063:Accidents, Traffic / Q000706:statistics & numerical data*; D000328:Adult; D000368:Aged; D001334:Automobile Driving; D015331:Cohort Studies; D003718:Denmark; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology; D012042:Registries; D014947:Wounds and Injuries / Q000209:etiology* / Q000628:therapy