A muscular lesion suggestive of focal myositis in a child with Proteus syndrome.
Proteus syndrome is a polymorphic hamartomatous disorder associated with a broad spectrum of rare congenital malformations. Many neoplasms have been linked to this condition, including lipomas, lymphangiomas, and hemangiomas. The authors describe a case of a congenital muscular lesion in a child with Proteus syndrome. This mass was painless but was growing out of proportion to her leg musculature. A magnetic resonance imaging scan and incisional biopsy showed findings consistent with focal myositis. The clinical, radiographic, and histologic characteristics of this previously undescribed lesion are discussed, with a brief review of the literature.
Andres
Brett M
BM
Department of Orthopaedic Surgery, The Johns Hopkins Hosital, Baltimore, MD, USA.
McCarthy
Edward F
EF
Frassica
Frank J
FJ
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007866:Leg; D008279:Magnetic Resonance Imaging; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000473:pathology; D009220:Myositis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D016715:Proteus Syndrome / Q000150:complications*; D011859:Radiography