title: [Severe malaria in children at the pediatric service of the Befelatanana Hospital Center at Antananarivo (Madagascar) in 1996-1998].
abstract: The definition of severe malaria is no longer limited to cerebral malaria, but it is as well extended to other clinical forms of the disease. The authors reported the epidemiological and clinical survey and evaluative aspects of severe malaria in Antananarivo. This retrospective study included 48 children less than 15 years old, hospitalized at the paediatric unit Debré of the Centre Hospitalier Universitaire de Befelatanana (Antananarivo) for severe malaria as defined by world Health Organization (WHO) criteria. The hospitalization frequency was 0.87%. Higher frequency was noticed for the children less than 5 years old, the sex-ratio was 1.4/1. The cerebral complications as seen in many African countries were the most frequent clinical form. The death rate was 14.58% and the proportional mortality was 1.07%, 2.1% of the patients had sequel. The improvement of severe malaria prognosis was not only on better equipment in intensive care wards, but also on improved and early diagnosis and management.
authors.affiliation: Hôpital général de Befelatanana, Centre Hospitalier Universitaire d'Antananarivo, BP 8394-101 Antananarivo-Madagascar.
authors.forename: H
authors.initials: H
authors.lastname: Raobijaona
authors.forename: C H
authors.initials: CH
authors.lastname: Randrianotahina
authors.forename: M
authors.initials: M
authors.lastname: Razanamparany
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data*; D006769:Hospitals, General / Q000706:statistics & numerical data*; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D008270:Madagascar / Q000453:epidemiology; D008288:Malaria / Q000145:classification / Q000453:epidemiology* / Q000628:therapy*; D016779:Malaria, Cerebral / Q000145:classification / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D012621:Seasons; D012720:Severity of Illness Index; D017678:Sex Distribution; D016896:Treatment Outcome