title: Transient MR signal changes in the splenium of the corpus callosum in rotavirus encephalopathy: value of diffusion-weighted imaging.
abstract: The authors report serial brain MR findings from a 2-year-old girl with rotavirus encephalopathy. The lesion in the splenium of the corpus callosum showed restricted proton diffusion, suggesting local cytotoxic edema. Diffusion-weighted images demonstrated the lesion more conspicuously than other techniques, such as fluid-attenuated inversion-recovery and T1- and T2-weighted images. The findings were reversible on follow-up MRI obtained 4 days later. Diffusion-weighted MRI is a potentially useful method for detecting early changes of rotavirus encephalopathy, although the mechanism of the restricted diffusion is not clearly identified.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Fukui Medical University, Fukui 910-1193, Japan.
authors.forename: Ritsuyo
authors.initials: R
authors.lastname: Kobata
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tsukahara
authors.forename: Akio
authors.initials: A
authors.lastname: Nakai
authors.forename: Akihiko
authors.initials: A
authors.lastname: Tanizawa
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Ishimori
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Kawamura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ushijima
authors.forename: Mitsufumi
authors.initials: M
authors.lastname: Mayumi
mesh_terms: D002675:Child, Preschool; D003337:Corpus Callosum / Q000473:pathology*; D018792:Encephalitis, Viral / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012400:Rotavirus Infections / Q000473:pathology*