title: [Fundic endocrine tumors and atrophic gastritis: the value of antrectomy].
abstract: We report two cases of fundic endocrine tumors associated with fundic atrophic gastritis-related hypergastrinemia and treated by antrectomy. About twenty infracentimetric tumors were observed in each patient and restrictively involved fundic mucosa. Antrectomy induced normalization of gastrinemia and the disappearance of fundic tumors, as soon as the 4(th) and 7(th) month. No recurrence was observed during the 5-year and 18-month follow-up time, respectively. We therefore consider that antrectomy may be regarded as a useful alternative treatment in the management of atrophic gastritis-related fundic endocrine tumors.
authors.affiliation: Service de Chirurgie Digestive et Générale, CHRU de Lille, France. guillem.philippe@wanadoo.fr
authors.forename: Philippe
authors.initials: P
authors.lastname: Guillem
authors.forename: Virginie
authors.initials: V
authors.lastname: Vlaeminck-Guillem
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Leteurtre
authors.forename: Richard
authors.initials: R
authors.lastname: Kornhauser
authors.forename: Antoine
authors.initials: A
authors.lastname: Cortot
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Wemeau
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Triboulet
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D001706:Biopsy; D002276:Carcinoid Tumor / Q000145:classification / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D004415:Dyspepsia / Q000209:etiology; D019861:Enterochromaffin-like Cells; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods*; D005748:Gastric Fundus / Q000601:surgery*; D005755:Gastrins / Q000097:blood; D005757:Gastritis, Atrophic / Q000150:complications* / Q000473:pathology; D005773:Gastroscopy; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011706:Pyloric Antrum / Q000601:surgery*; D013274:Stomach Neoplasms / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D005755:Gastrins