[Parosteal osteosarcoma (POS). Clinical and therapeutic aspects].
Parosteal osteosarcoma is a malignant bone-forming tumor, which is characterized by its superficial origin and its high structural differentiation. Because of the radiological and histological variability, finding the right diagnosis is a great challenge for physicians, radiologists, and pathologists, especially at the time of primary manifestation. Usually there is a low-grade malignancy. Often a benign tumor is imitated so that finding the correct diagnosis is indispensable. Wide resection with sufficient margin is the adequate therapy. High-grade parosteal osteosarcoma needs adjuvant chemotherapy. Our own experience with secondary dedifferentiation and the possibility of primary undergrading shows that regarding diagnostics, operative therapy, and follow-up parosteal osteosarcoma should be treated like conventional osteosarcoma.
Bernd
L
L
Sektion Orthopädische Onkologie und Septische Orthopädische Chirurgie, Stiftung Orthopädische Universitätsklinik Heidelberg, Germany.
Saleh
H
H
Zahlten-Hinguranage
A
A
Zeifang
F
F
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D016025:Bone Transplantation; D005260:Female; D005266:Femoral Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D005500:Follow-Up Studies; D005593:Fracture Fixation, Internal; D006801:Humans; D006811:Humerus; D008297:Male; D008875:Middle Aged; D018217:Osteosarcoma, Juxtacortical / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D019736:Prostheses and Implants; D011859:Radiography; D013977:Tibia; D013997:Time Factors