Agrocybe cylindracea lectin is a member of the galectin family.
The complete amino acid sequence of Agrocybe cylindracea lectin was determined from the peptides obtained by chemical cleavages and enzymatic hydrolyses. The sequence shows 19.1% and 36.8% identity with those of human galectin-1 and Coprinus lectin-1, a fungal galectin, respectively. Seven residues, which are commonly found in carbohydrate recognizing domain (CRD) of galectins, were conserved. However, several insertions in the sequence, compared with those of human galectin-1 and Coprinus lectin-1, suggest that beta-strands S2, F3, and S4 and the loop structures between beta-strands F2 & S3 and F5 & S2 are different from those of galectins reported so far.
Yagi
F
F
Department of Biochemical Science and Technology, Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto Kagoshima 890-0065, Japan. fyagi@chem.agri.kagoshima-u.ac.jp
Hiroyama
H
H
Kodama
S
S
D000595:Amino Acid Sequence; D001487:Basidiomycota / Q000737:chemistry*; D001665:Binding Sites; D002236:Carbohydrate Conformation; D050260:Carbohydrate Metabolism; D003302:Coprinus / Q000737:chemistry; D004798:Enzymes / Q000378:metabolism; D037483:Galectin 1 / Q000031:analogs & derivatives* / Q000235:genetics; D006801:Humans; D037102:Lectins / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry; D017386:Sequence Homology, Amino Acid
D004798:Enzymes; D037483:Galectin 1; C445499:LGALS1 protein, human; D037102:Lectins; D011506:Proteins