Generalised infantile myofibromatosis with intracranial involvement: imaging findings in a newborn.
Infantile myofibromatosis is a disorder of infancy and early childhood characterised by single or multiple nodular lesions localised to bone, muscle, viscera, subcutaneous tissue or central nervous system. These pseudotumours contain smooth muscle and fibroblasts. The prognosis depends on the amount, as well as location, of the lesions. We present the radiological findings on plain films, US and MRI of a newborn who presented at birth with multiple organ involvement, including the CNS. To our knowledge, the comprehensive imaging features of such severe and multifocal involvement have not previously been reported.
Spadola
Luca
L
Department of Paediatric Radiology, Hôpital Universitaire des Enfants, 6 Avenue Willy Donzé, 1211 Geneva 14, Switzerland. Ispadola@mac.com
Anooshiravani
Mehrak
M
Sayegh
Yasmine
Y
Jéquier
Sigrid
S
Hanquinet
Sylviane
S
D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D018224:Myofibromatosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography; D014463:Ultrasonography