Efficient interstrand excess electron transfer in PNA:DNA hybrids.
PNA:DNA strands were prepared containing a flavin electron donor and a thymine dimer acceptor, which gives a strand break upon single electron reduction. With these constructs, it was confirmed that an excess electron transfer through the base stack can be efficient in an interstrand fashion. The effect of an increased distance, a changed sequence, and stacking was explored.
Cichon
Michaela K
MK
Department of Chemistry, Philipps-University Marburg, D-35032 Marburg, Germany.
Haas
Clemens H
CH
Grolle
Friederike
F
Mees
Alexandra
A
Carell
Thomas
T
D004247:DNA / Q000737:chemistry*; D004583:Electrons; D005415:Flavins / Q000737:chemistry; D020135:Peptide Nucleic Acids / Q000737:chemistry*; D010777:Photochemistry; D011740:Pyrimidine Dimers / Q000737:chemistry
D005415:Flavins; D020135:Peptide Nucleic Acids; D011740:Pyrimidine Dimers; D004247:DNA