title: [The protective effects of Lycium barbarum polysaccharide on alloxan-induced isolated islet cells damage in rats].
abstract: OBJECTIVE
  To study the effects of Lycium barbarum polysaccharide (LBP) on alloxan-induced isolated islet cells damage in rats.
  
  
  METHODS
  Isolated islet cells from SD rat were cultured in vitro. SOD activity and MDA content in rat islet cells incubated with alloxan or alloxan combined LBP were measured.
  
  
  RESULTS
  Alloxan induced a significant decrease in SOD activity and a increase in MDA production, which were inhibited by LBP.
  
  
  CONCLUSIONS
  LBP had protective effects on alloxan-induced isolated rat islet ceus damage.
authors.affiliation: School of Life Science, East China Normal University, Shanghai 200062.
authors.forename: Manyan
authors.initials: M
authors.lastname: Xu
authors.forename: Hongfeng
authors.initials: H
authors.lastname: Zhang
authors.forename: Yufei
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000496:Alloxan; D000818:Animals; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D007515:Islets of Langerhans / Q000473:pathology*; D032305:Lycium / Q000737:chemistry*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D020011:Protective Agents / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000187:drug effects
chemical_list: D004365:Drugs, Chinese Herbal; D011134:Polysaccharides; D020011:Protective Agents; D008315:Malondialdehyde; D000496:Alloxan; D013482:Superoxide Dismutase