2-azabenzonorbornanes from 7-azabenzonorbornanols by a nitrogen-directed neophyl-type radical rearrangement.
[reaction: see text] Barton deoxygenation of 7-azabenzonorbornanols leads to a synthetically useful neophyl-like rearrangement to give 2-azabenzonorbornane derivatives in 64-90% yields.
Hodgson
David M
DM
Dyson Perrins Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QY, UK. david.hodgson@chem.ox.ac.uk
Bebbington
Magnus W P
MW
Willis
Paul
P