title: Clinical risk factors for deep venous thrombosis in pregnancy and the puerperium.
abstract: Thromboembolic events are among the leading causes of maternal mortality. Mutations in the genes for clotting factors are known, but anamnestic factors can be found in a proportion of women with deep venous thromboses (DVT) during pregnancy and the puerperium. We here describe the clinical factors and pregnancy outcomes of such a group of 70 women who were all operated on for DVT. Highest risk is conferred by a familial history of clotting disease and by known mutations of the clotting factors. This might be used to target a high risk group for preventive treatment.
authors.affiliation: Department of Gynecology and Obstetrics, University Hospital Düsseldorf, Germany.
authors.forename: Boris
authors.initials: B
authors.lastname: Tutschek
authors.forename: Sabine
authors.initials: S
authors.lastname: Struve
authors.forename: Tamme
authors.initials: T
authors.lastname: Goecke
authors.forename: Michael
authors.initials: M
authors.lastname: Pillny
authors.forename: Rainer
authors.initials: R
authors.lastname: Zotz
authors.forename: Andrea
authors.initials: A
authors.lastname: Gerhardt
authors.forename: Matthias
authors.initials: M
authors.lastname: Beckmann
mesh_terms: D000293:Adolescent; D000328:Adult; D002585:Cesarean Section; D036861:Delivery, Obstetric / Q000379:methods; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D011272:Pregnancy, Multiple; D011644:Puerperal Disorders / Q000453:epidemiology*; D012307:Risk Factors; D014427:Twins; D020246:Venous Thrombosis / Q000453:epidemiology* / Q000601:surgery