title: Lessons learned from the Marmara disaster: Time period under the rubble.
abstract: OBJECTIVE
  To investigate the effect of the time period under the rubble on morbidity and mortality of the crush-syndrome patients after the catastrophic Marmara earthquake that struck northwestern Turkey in August 1999.
  
  
  METHODS
  Observational study.
  
  
  METHODS
  Consecutive admissions to emergency and intensive care units of 35 reference hospitals that treated the renal victims.
  
  
  METHODS
  Analysis of questionnaires obtained from these hospitals.
  
  
  METHODS
  A total of 539 of 639 crush-syndrome patients whose time under the rubble was identified in the questionnaires.
  
  
  RESULTS
  Mean time under the rubble was 11.7 +/- 14.3 hrs (median, 8 hrs; interquartile range, 6 hrs; range, 0.5-135 hrs). The highest number of patients was entrapped within the 5-8 hrs time stratum, and by the end of 48 hrs, 97% of the victims had been rescued. Nondialyzed victims spent a longer duration under the rubble than dialyzed ones (15.9 +/- 23.1 hrs [median, 7 hrs; interquartile range, 8.5 hrs] vs. 10.3 +/- 9.5 hrs [median, 8 hrs; interquartile range, 6 hrs), p <.001)]. Likewise, in the strata of longer time under the rubble, the percentage of survivors was higher (p =.07). Time under the rubble correlated positively with the number of amputated extremities (p <.001) and admission platelet count (p <.001), and it correlated negatively with admission serum albumin (p <.001). The victims entrapped for >50 hrs (n = 6) were characterized by lower figures of admission blood urea nitrogen (p =.04), serum creatinine (p =.003), hemodialysis sessions, and duration of hemodialysis support (p =.005, for both analyses) compared with victims whose time under the rubble was shorter.
  
  
  CONCLUSIONS
  Rescue efforts should continue at least for 5 days after the disaster. Time under the rubble is not an adverse prognostic indicator of survival or renal dysfunction for the patients of crush syndrome, probably because only the victims with mild or moderate injuries can survive under the rubble for longer durations.
authors.affiliation: Department of Nephrology, Istambul School pf Medicine, Turkey.
authors.forename: Mehmet Sukru
authors.initials: MS
authors.lastname: Sever
authors.forename: Ekrem
authors.initials: E
authors.lastname: Erek
authors.forename: Raymond
authors.initials: R
authors.lastname: Vanholder
authors.forename: Cetin
authors.initials: C
authors.lastname: Ozener
authors.forename: Mahmut
authors.initials: M
authors.lastname: Yavuz
authors.forename: Seyit Mehmet
authors.initials: SM
authors.lastname: Kayacan
authors.forename: Hulya
authors.initials: H
authors.lastname: Ergin
authors.forename: Suheyla
authors.initials: S
authors.lastname: Apaydin
authors.forename: Mehmet
authors.initials: M
authors.lastname: Cobanoglu
authors.forename: Osman
authors.initials: O
authors.lastname: Donmez
authors.forename: Yunus
authors.initials: Y
authors.lastname: Erdem
authors.forename: Norbert
authors.initials: N
authors.lastname: Lameire
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003444:Crush Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D003657:Decision Making; D004190:Disasters; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D012044:Regression Analysis; D006435:Renal Dialysis / Q000706:statistics & numerical data; D018635:Rescue Work; D018709:Statistics, Nonparametric; D015996:Survival Rate; D013997:Time Factors; D014421:Turkey / Q000453:epidemiology