The autolysin of Porphyromonas gingivalis is involved in outer membrane vesicle release.
An autolysin mutant of Porphyromonas gingivalis was constructed and its outer membrane vesicle production was compared to that of wild-type strain 381. The autolysin mutant produced elevated levels of vesicles relative to the parental strain. It is suggested that vesicle formation of this organism may be regulated by cell wall turnover.
Hayashi
Jun-ichiro
J
Department of Oral Biology, State University of New York, 3435 Main Street, Buffalo, NY 14214, USA.
Hamada
Nobushiro
N
Kuramitsu
Howard K
HK
D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism*; D002455:Cell Division; D002462:Cell Membrane / Q000201:enzymology; D003470:Culture Media; D008854:Microscopy, Electron; D009238:N-Acetylmuramoyl-L-alanine Amidase / Q000502:physiology*; D016966:Porphyromonas gingivalis / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure; D014617:Vacuoles / Q000502:physiology / Q000648:ultrastructure; D014774:Virulence
D001425:Bacterial Outer Membrane Proteins; D003470:Culture Media; D009238:N-Acetylmuramoyl-L-alanine Amidase