[Turner's syndrome: growth and clinical description of 83 Chilean girls].
BACKGROUND
Short stature is the main feature of patients with Turner's syndrome. There is limited information regarding the spontaneous growth of these patients in Chile.


OBJECTIVE
To develop a specific growth chart for Chilean patients with Turner's syndrome.


METHODS
We retrospectively analyzed 668 height measurements from 85 Chilean girls, born after 1968, with 45XO karyotype (minimum 15%), and without an Y chromosome fragment. Patients with hormonal therapy, such as growth hormone or estrogen, except thyroid hormone replacement, were excluded.


RESULTS
The karyotypes were 60% 45XO, 25% 45XO, 46XX, and 15% other complex mosaics. The birth length was 46.8 +/- 2.1 cm. The final height of our patients was 138,20 +/- 7.0 cm.


CONCLUSIONS
The final height achieved by our patients, is similar to Argentinian and Japanese patients, but is below the mean stature reported for Scandinavian and Northamerican patients who achieve a mean adult height of approximately 147 and 142 cm respectively. The birth length is also lower than that reported in those studies.
Román
Rossana
R
Instituto de Investigaciones Materno-Infantil, Facultad de Medicina, Campus Centro, Universidad de Chile. rossana.roman@terra.cl
Vallejos
María Eliana
ME
Muñoz
Mónica
M
Schneider
Ruth
R
Youlton
Ronald
R
Henriquez
Cecilia
C
Cassorla
Fernando
F
D000293:Adolescent; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D002677:Chile / Q000208:ethnology; D005260:Female; D006128:Growth; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007621:Karyotyping; D012189:Retrospective Studies; D014424:Turner Syndrome / Q000235:genetics / Q000503:physiopathology*