Adult cellular rhabdomyoma of the heart: a report of 3 cases.
We present 3 adults with cardiac rhabdomyomas, 2 in the atria and 1 in the right ventricle. One atrial tumor was discovered incidentally, and 1 resulted in supraventricular tachycardia. The ventricular lesion caused ventricular tachycardia. Compared with congenital rhabdomyomas, the tumors are relatively cellular, the cells are smaller, there are few spider cells, and there is evidence of cell proliferation. Two of the 3 tumors demonstrated spindling in contrast to adult rhabdomyomas of the head and neck. Although surgical excision was possible in all patients, long-term follow-up will be required to determine the true biologic behavior of these neoplasms.
Burke
Allen P
AP
Department of Cardiovascular Pathology, Armed Forces Institute of Pathology, Washington DC 20306-6000, USA.
Gatto-Weis
Cara
C
Griego
Janet E
JE
Ellington
Kenneth S
KS
Virmani
Renu
R
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D005260:Female; D006325:Heart Atria / Q000737:chemistry / Q000473:pathology; D006338:Heart Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006352:Heart Ventricles / Q000737:chemistry / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D012207:Rhabdomyoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D013617:Tachycardia, Supraventricular / Q000209:etiology / Q000473:pathology; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000473:pathology; D016896:Treatment Outcome
D015415:Biomarkers