The usefulness of transcutaneous oximetry in assessing the success of percutaneous transluminal angioplasty.
OBJECTIVE
to identify whether monitoring transcutaneous oxygen pressure (TcpO(2)) can provide an objective method of assessing the results of PTA.


METHODS
fifty-seven patients (39 Fontaine stage II, <18 stage III or IV) had ABI, TcpO(2) at rest (stages III and IV) or during exercise (stage II) and total work capacity of the leg (stage II) measured before, 24-48 h, 2 and 6 weeks after PTA.


RESULTS
a significant increase of ABI in both groups of patients was detected immediately after successful PTA. TcpO(2) measured on the foot at rest increased in stages III and IV patients immediately after PTA (from 14 (IQR)18 to 25 (IQR)32 mmHg,p <0.05) and again after 6 weeks in comparison to follow up two (from 25 (IQR)32 to 35 (IQR)21 mmHg,p <0.05). In patients in stage II TcpO(2) decreased in a typical fashion during exercise. Total oxygen drop was most evident before treatment (352 (IQR)458 smmHg) and decreased significantly immediately after PTA (148 (IQR)175 smmHg, p<0.001).


CONCLUSIONS
TcpO(2) measurement is an useful method for investigating the success of PTA. While the macrocirculation improves immediately after successful recanalisation, complete normalisation of the microcirculation may take some weeks, especially stages III and IV disease.
Stalc
M
M
Department of Vascular Disease, Clinical Centre, Ljubljana, Slovenija.
Poredos
P
P
D000368:Aged; D000800:Angioplasty, Balloon; D001157:Arterial Occlusive Diseases / Q000097:blood* / Q000503:physiopathology / Q000628:therapy*; D001785:Blood Gas Monitoring, Transcutaneous; D001794:Blood Pressure / Q000502:physiology; D001795:Blood Pressure Determination; D015444:Exercise / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000097:blood* / Q000503:physiopathology / Q000628:therapy*; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome