Histochemical and immunohistochemical features of a case showing association of meningioma and prolactinoma containing amyloid.
We report the rare case of a 43-year-old woman with a simultaneous meningioma of the sphenoid wing and an amyloid-containing prolactinoma. The patient, who presented with a 17-year history of amenorrhea, and galactorrhea, was found to have a 10-mm mass in the pituitary gland. During excision of this lesion, another mass was noticed, which was located in the sphenoid wing. Both lesions were completely excised. Histopathological examination revealed that the pituitary tumor was a prolactinoma with diffuse amyloid deposition and that the second tumor was a typical meningioma. The coexistence of a prolactinoma containing amyloid and a meningioma is very rare in the literature, so this case is presented here with its histochemical and immunohistochemical features. We discuss the significance of prolactinoma containing amyloid and the simultaneous presentation of these two tumors.
Canda
Tülay
T
Dokuz Eylül University, Faculty of Medicine, Department of Pathology, 35340 Inciralti-Izmir, Turkey. tulay.canda@deu.edu.tr
Sengiz
Selma
S
Canda
M Serefettin
MS
Acar
Umit D
UD
Erbayraktar
R Serhat
RS
Yilmaz
H Sinan
HS
D000328:Adult; D000682:Amyloid / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008577:Meningeal Neoplasms / Q000378:metabolism* / Q000473:pathology; D008579:Meningioma / Q000378:metabolism* / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000378:metabolism* / Q000473:pathology; D010911:Pituitary Neoplasms / Q000378:metabolism* / Q000473:pathology; D015175:Prolactinoma / Q000378:metabolism* / Q000473:pathology
D000682:Amyloid