title: Synthesis of chiral chromium tricarbonyl labeled thymine PNA monomers via the Ugi reaction.
abstract: [reaction: see text] Ugi condensation was used to synthesize the first examples of chiral racemic Ar.Cr(CO)(3) labeled peptide nucleic acid (PNA) monomers bearing the organometallic moiety linked to the alpha-carbon of the glycine unit.
authors.affiliation: CNR Istituto di Scienze e Tecnologie Molecolari e Dipartimento di Chimica Organica e Industriale, University of Milan, Via C. Golgi 19, I-20133 Milano, Italy.
authors.forename: Clara
authors.initials: C
authors.lastname: Baldoli
authors.forename: Stefano
authors.initials: S
authors.lastname: Maiorana
authors.forename: Emanuela
authors.initials: E
authors.lastname: Licandro
authors.forename: Giovanna
authors.initials: G
authors.lastname: Zinzalla
authors.forename: Dario
authors.initials: D
authors.lastname: Perdicchia
mesh_terms: D017608:Chromium Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D020135:Peptide Nucleic Acids / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013941:Thymine / Q000031:analogs & derivatives* / Q000138:chemical synthesis*
chemical_list: D017608:Chromium Compounds; D020135:Peptide Nucleic Acids; D013941:Thymine