[Detection of residue of nasopharyngeal carcinoma with FDG PET].
OBJECTIVE
The use of F-18-fluoro-2-deoxy-d-glucose positron emission tomography (FDG PET) in detection of suspected residue of malignant tumor after treatment has become one of the most important targets of study in radiotherapy. This study was designed to evaluate FDG PET in detection of suspected residue of nasopharyngeal carcinoma (NPC) after treatment, in comparison with CT imaging.


METHODS
Twenty-five patients with clinically suspected residue of NPC did FDG PET Scanning, 23 of them also examine with CT imaging. The diagnosis of residue were confirmed by pathology or clinical follow-up.


RESULTS
FDG PET correctly detected residue in 19/25 patients. There were 4 false positive and 2 false negative patients. The accuracy of FDG PET was 76.0% (19/25), compared to 52.2% (12/23) of CT scan. Eleven of 23 patients did not show any residue by CT scan, while, FDG PET scan showed significantly increased FDG metabolism, indicating residue in 2 of these patients. In 7 patients, both CT and FDG PET indicated residue tumor.


CONCLUSIONS
Compared with CT imaging, FDG PET has a higher accuracy in detection of residue nasopharyngeal carcinoma after treatment.
Chen
Ying-rui
YR
Department of Radiation Oncology, People's Hospital of Guangdong, Guangzhou 510080, P. R. China.
Gu
Mei-xin
MX
Li
Wei-xiong
WX
Pan
Yi
Y
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging*; D011859:Radiography; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed / Q000379:methods
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18