SV40 and human tumours: myth, association or causality?
An increasing number of scientific reports have described evidence for a polyomavirus, simian virus 40, in a highly select group of human tumours. How did a simian virus infect humans and is the virus a passenger in tumours or is it important in their pathogenesis?
Gazdar
Adi F
AF
Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Centre, Dallas, Texas 75390, USA.
Butel
Janet S
JS
Carbone
Michele
M
D000818:Animals; D002471:Cell Transformation, Neoplastic; D004198:Disease Susceptibility; D016679:Genome, Viral; D006801:Humans; D008654:Mesothelioma / Q000209:etiology / Q000821:virology; D009369:Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000821:virology*; D013539:Simian virus 40 / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology*