Are there naturally occurring pleomorphic bacteria in the blood of healthy humans?
Dark-field microscopy of blood from healthy individuals revealed the existence of pleomorphic microorganisms. These bacteria exhibited limited growth and susceptibility to antibiotics and could be detected by fluorescent in situ hybridization and flow cytometry. They were further characterized by analysis of their 16S rRNA and gyrB genes.
McLaughlin
Richard W
RW
Faculty of Dentistry, McGill University, Montreal, Quebec H3A 2B4, Canada.
Vali
Hojatollah
H
Lau
Peter C K
PC
Palfree
Roger G E
RG
De Ciccio
Angela
A
Sirois
Marc
M
Ahmad
Darakhshan
D
Villemur
Richard
R
Desrosiers
Marcel
M
Chan
Eddie C S
EC
D001419:Bacteria / Q000235:genetics / Q000254:growth & development* / Q000302:isolation & purification* / Q000648:ultrastructure; D001769:Blood / Q000382:microbiology*; D027081:DNA Gyrase / Q000235:genetics; D004269:DNA, Bacterial / Q000032:analysis; D004275:DNA, Ribosomal / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008854:Microscopy, Electron; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S; D027081:DNA Gyrase