Options available--from start to finish--for obtaining data from DNA microarrays II.
Microarray technology has undergone a rapid evolution. With widespread interest in large-scale genomic research, an abundance of equipment and reagents have now become available and affordable to a large cross section of the scientific community. As protocols become more refined, careful investigators are able to obtain good quality microarray data quickly. In most recent times, however, perhaps one of the biggest obstacles researchers face is not the manufacture and use of microarrays at the bench, but storage and analysis of the array data. This review discusses the most recent equipment, reagents and protocols available to the researcher, as well as describing data analysis and storage options available from the evolving field of microarray informatics.
Holloway
Andrew J
AJ
The Ian Potter Foundation Centre for Cancer Genomics and Predictive Medicine and The Trescowthick Research Laboratories, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett Street, Melbourne 8006, Victoria, Australia.
van Laar
Ryan K
RK
Tothill
Richard W
RW
Bowtell
David D L
DD
D004247:DNA / Q000032:analysis*; D018076:DNA, Complementary / Q000235:genetics; D003625:Data Collection / Q000379:methods*; D005544:Forecasting; D015894:Genome, Human; D006801:Humans; D016247:Information Storage and Retrieval; D008490:Medical Informatics / Q000639:trends; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011786:Quality Control; D012107:Research Design; D017422:Sequence Analysis, DNA; D013223:Statistics as Topic
D018076:DNA, Complementary; D004247:DNA