title: Insulinoma in a normoglycaemic dog with low serum fructosamine.
abstract: An insulinoma was diagnosed in an eight-year-old, male golden retriever. Four fasted serum glucose concentrations were within the reference values over a seven-week period. Two serum fructosamine values over the same seven-week period were both low. An exploratory laparotomy and histopathology of an excised pancreatic nodule confirmed the diagnosis of insulinoma. This report demonstrates that a dog with a histologically confirmed insulinoma can have normal fasting serum glucose concentrations on multiple assays. It also demonstrates that fructosamine assays may be helpful in the diagnostic evaluation of normoglycaemic dogs with clinical signs suggestive of insulinoma.
authors.affiliation: Queen's Veterinary School Hospital, University of Cambridge, Madingley Road, Cambridge CB3 OES.
authors.forename: R J
authors.initials: RJ
authors.lastname: Mellanby
authors.forename: M E
authors.initials: ME
authors.lastname: Herrtage
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D001786:Blood Glucose; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D004285:Dogs; D019270:Fructosamine / Q000097:blood* / Q000172:deficiency*; D007328:Insulin / Q000097:blood; D007340:Insulinoma / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D012709:Serum Albumin
chemical_list: D001786:Blood Glucose; D007328:Insulin; D012709:Serum Albumin; D019270:Fructosamine