title: Orchestrating the unfolded protein response in health and disease.
authors.affiliation: Department of Biological Chemistry, Howard Hughes Medical Institute, University of Michigan Medical Center, Ann Arbor 48109-0650, USA. kaufmanr@umich.edu
authors.forename: Randal J
authors.initials: RJ
authors.lastname: Kaufman
mesh_terms: D051702:Activating Transcription Factor 6; D017209:Apoptosis; D004268:DNA-Binding Proteins / Q000378:metabolism; D003920:Diabetes Mellitus / Q000235:genetics / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism; D004722:Endoribonucleases; D004789:Enzyme Activation; D030342:Genetic Diseases, Inborn / Q000235:genetics / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D020138:Hyperhomocysteinemia / Q000235:genetics / Q000378:metabolism; D007511:Ischemia / Q000378:metabolism; D008565:Membrane Proteins; D008954:Models, Biological; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism; D015388:Organelles / Q000378:metabolism; D017510:Protein Folding; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism; D012326:RNA Splicing; D015398:Signal Transduction; D013312:Stress, Physiological / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism; D014777:Virus Diseases / Q000209:etiology / Q000378:metabolism; D019892:eIF-2 Kinase / Q000378:metabolism
chemical_list: D051702:Activating Transcription Factor 6; D004268:DNA-Binding Proteins; D004722:Endoribonucleases; D005947:Glucose; D008565:Membrane Proteins; D017346:Protein Serine-Threonine Kinases; D014157:Transcription Factors; D019892:eIF-2 Kinase; C497111:ATF6 protein, human; C403982:ERN2 protein, human