title: [Predictive value of consultation reasons in the diagnosis of leprosy in Bamako (Mali)].
abstract: BACKGROUND
  One of the weak points in the strategy for eliminating leprosy is the poor quality of screening. To overcome this, the World Health Organization (WHO) encourages endemic countries to run campaigns for the elimination of leprosy by circulating educational messages and mobilizing the medical community for early screening of cases. The aim of our study was to identify the motives for consultation with high predictive value for the diagnosis of leprosy and to determine the late diagnosis factors and hence assist the staff on site to improve the results of their leprosy elimination campaigns.
  
  
  METHODS
  The study consisted, during the second trimester of 1999, in interviewing all the patients consulting for the first time the Marchoux Institute or the units screening for leprosy in the Bamako area. The interview recorded the motives for consultation, the delay before consulting and the reasons for late consulting. To assess their positive predictive value, the motives for consultation were related to the diagnosis retained (leprosy or not).
  
  
  RESULTS
  One thousand one hundred and seventy seven patients were interviewed. The motive for consulting, "suspected leprosy", scored the highest positive predictive value (PPV) (80 p. 100): 12 cases of leprosy were diagnosed by 15 consultants having suspected leprosy. Neurological problems were the second motive for consultation (PPV=61.9 p. 100). The most frequent motive for consultation was spots or "macules" (20 p. 100 of consultations), but only provided a positive predictive value of 19 p. 100. Prior consultations and non-specialized treatments were identified as factors of delay in diagnosing leprosy (P<0.001).
  
  
  CONCLUSIONS
  Diagnosis of leprosy cannot be based on the motives for dermatological consultation alone. The macules are the most apparent signs, but of low predictive value. Nevertheless, they are an early but non-specific sign of leprosy and are often neglected by the patient. Other than macules, attention must be paid to the neurological signs (dysesthesia, motor disorders) when screening for leprosy. These signs may appear early on, or be observed at a late stage in the progression of the disease.
authors.affiliation: Institut Marchoux, B.P. 251, Bamako, Mali. skeita@ml.refer.org
authors.forename: S
authors.initials: S
authors.lastname: Keita
authors.forename: A
authors.initials: A
authors.lastname: Tiendrebeogo
authors.forename: D
authors.initials: D
authors.lastname: Berthe
authors.forename: O
authors.initials: O
authors.lastname: Faye
authors.forename: H T
authors.initials: HT
authors.lastname: N'diaye
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003627:Data Interpretation, Statistical; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007918:Leprosy / Q000175:diagnosis* / Q000517:prevention & control; D008302:Mali; D008875:Middle Aged; D013997:Time Factors; D014944:World Health Organization