title: Animal retroviral infections suggest third kind of potential treatment: HIV harm reduction.
abstract: Besides antivirals and immune-based treatments, a third approach is to reduce the harm caused indirectly by HIV, which is probably more important than the direct killing of infected cells. Some animals do not get sick when infected with HIV-like viruses despite very high viral loads--suggesting that they have successfully evolved to tolerate the virus instead of eradicating or suppressing it. Understanding how they do so might lead to a new kind of HIV treatment.
authors.forename: John S
authors.initials: JS
authors.lastname: James
mesh_terms: D000818:Animals; D018791:CD4 Lymphocyte Count; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D011323:Primates; D012192:Retroviridae Infections / Q000662:veterinary*; D019562:Viral Load