Ropinirole in restless leg syndrome.
Restless leg syndrome (RLS) is a disease of unknown etiology, characterized by paresthesias and an irresistible desire to move the legs. Dopaminergic mechanisms have been implicated in the pathogenesis of this disorder. Dopamine agonists have been used to treat RLS. This paper describes the use of ropinirole, a non-ergoline dopamine agonist, in the treatment of RLS. Polysomnograms after treatment, as well as patient assessment of their symptoms, showed clinical improvement.
Ahmed
Iftekhar
I
University of Missouri-Kansas City, Department of Neurology and Medical Education, Trinity Lutheran Hospital, USA.
D018491:Dopamine Agonists / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007211:Indoles / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012148:Restless Legs Syndrome / Q000188:drug therapy*; D014481:United States
D018491:Dopamine Agonists; D007211:Indoles; C046649:ropinirole