title: Bleeding after excision of breast lumps.
abstract: Bleeding complications after excision of lumps in the breast are common and may be related to the prescription of heparin for prophylaxis of thrombo-embolism. Between I June 1997 and I January 2000, 206 lumps of the breast were removed in 186 patients. All patients received a low molecular weight heparin as a prophylaxis for deep venous thrombosis. The number of bleeding complications was 23 (11%). Patients operated on the day of admission had more bleeding complications than those who were operated on the day after admission (19/145 (13%) compared with 4/61 (7%)). The difference was not significant (p = 0.26). Smoking and use of antihypertensive medication were registered more often in patients without bleeding complications. Lumpectomy of the breast is an operation with a lot of bleeding complications. This might be related to the timing of deep venous thrombosis prophylaxis.
authors.affiliation: Department of General Surgery, St Joseph Hospital, Veldhoven, The Netherlands. xrbakker@planet.nl
authors.forename: Xander R
authors.initials: XR
authors.lastname: Bakker
authors.forename: Rudi M H
authors.initials: RM
authors.lastname: Roumen
mesh_terms: D000556:Ambulatory Surgical Procedures; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage* / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D015412:Mastectomy, Segmental / Q000009:adverse effects* / Q000379:methods; D009426:Netherlands / Q000453:epidemiology; D019106:Postoperative Hemorrhage / Q000139:chemically induced* / Q000453:epidemiology; D011300:Preoperative Care; D012189:Retrospective Studies; D018570:Risk Assessment; D020246:Venous Thrombosis / Q000517:prevention & control*
chemical_list: D006495:Heparin, Low-Molecular-Weight