[Value of MRI findings in Gayet-Wernicke encephalopathy].
Wernicke encephalopathy (Wernicke-Korsakoff encephalopathy) is related to thiamine deficiency. We report the MRI findings in four patients with visualization of bilateral and symmetrical hyperintense foci on T2W and FLAIR images involving the periaqueductal gray matter, the mamillary bodies and around the third ventricle. Diffusion weighted images obtained in two patients demonstrated mild hypersignal in the same areas. Contrast enhancement within the mamillary bodies was noted in one patient. Follow-up MRI obtained in three patients showed rapid regression of signal abnormalities without correlation with good clinical outcome.
Lenz
V
V
Service de Radiologie 2, CHU de Hautepierre, avenue Molière, 67098 Strasbourg Cedex, France.
Vargas
M I
MI
Bin
J F
JF
Bogorin
A
A
Grebici-Guessoum
M
M
Jacques
C
C
Marin
H
H
Zöllner
G
G
Dietemann
J L
JL
D000328:Adult; D000437:Alcoholism / Q000150:complications; D003287:Contrast Media; D018450:Disease Progression; D005260:Female; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008326:Mammillary Bodies / Q000473:pathology; D008875:Middle Aged; D010487:Periaqueductal Gray / Q000473:pathology; D012680:Sensitivity and Specificity; D013832:Thiamine Deficiency / Q000150:complications; D020542:Third Ventricle / Q000473:pathology; D014899:Wernicke Encephalopathy / Q000175:diagnosis* / Q000209:etiology
D003287:Contrast Media; D005682:Gadolinium