title: Perilymphatic fistula following trans-tympanic trauma: a clinical case presentation and review of the literature.
abstract: The perilymphatic fistula is constituted by an anomalous connection between the perilymphatic space and the middle ear. The principal accuses are to be sought in the intracranial pressure increasement, cranial traumas, barotraumas, congenital anomalies, trans-tympanic traumas, etc. Stapes's dislocation in the vestibule and the fracture of the platina are the most frequent pathogenic mechanisms. In clinical practice, the diagnosis remains a problem rather debated, even if the clinical pattern, the laboratory investigations, the diagnostic images and the tympanic exploration, all together can confirm, in the majority of the cases, the diagnostic suspect. This article presents a clinical case of a transtympanic trauma with perilymphatic fistula caused by a foreign body. The peculiarity of this case must be set in relation with both the aetiopathogenesis of the labyrinthine lesion and the severity of the symptomatology caused by it.
authors.affiliation: ENT Department, University of Rome Tor Vergata.
authors.forename: E
authors.initials: E
authors.lastname: Bruno
authors.forename: M
authors.initials: M
authors.lastname: Alessandrini
authors.forename: S
authors.initials: S
authors.lastname: Russo
authors.forename: G
authors.initials: G
authors.lastname: D'Erme
authors.forename: R
authors.initials: R
authors.lastname: Nucci
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003052:Cochlear Aqueduct; D004427:Ear Diseases / Q000209:etiology*; D005402:Fistula / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013256:Steroids; D014432:Tympanic Membrane / Q000293:injuries*; D014947:Wounds and Injuries / Q000150:complications
chemical_list: D000893:Anti-Inflammatory Agents; D013256:Steroids