Aggregation of f-actin in olfactory glomeruli: a common feature of glomeruli across phyla.
Using fluorophore-conjugated phalloidin, we show that filamentous (F)-actin is strongly aggregated in olfactory glomeruli within primary olfactory centers of vertebrates and insects. Our comparative study demonstrates that aggregation of F-actin is a common feature of glomeruli across phyla, and is independent of glomerular architecture and/or the presence or absence of cellular borders around glomeruli formed by neurons or glial cells. The distribution of F-actin in axonal and dendritic compartments within glomeruli, however, appears different between vertebrates and insects. The potential role of the actin-based cytoskeleton in synaptic and structural plasticity within glomeruli is discussed.
Rössler
Wolfgang
W
Physiologisches Institut, Universität Göttingen, Humboldtallee 23, Germany. roessler@biozentrum.uni-wuerzburg.de
Kuduz
Josko
J
Schürmann
Friedrich W
FW
Schild
Detlev
D
D000199:Actins / Q000378:metabolism*; D000557:Ambystoma; D000818:Animals; D001369:Axons / Q000378:metabolism; D003712:Dendrites / Q000378:metabolism; D006054:Goldfish; D007150:Immunohistochemistry; D007313:Insecta; D051379:Mice; D018613:Microscopy, Confocal; D009830:Olfactory Bulb / Q000378:metabolism*; D009833:Olfactory Pathways / Q000378:metabolism; D018034:Olfactory Receptor Neurons / Q000378:metabolism*; D010590:Phalloidine / Q000737:chemistry; D011419:Propidium / Q000737:chemistry; D051381:Rats; D012679:Sense Organs / Q000033:anatomy & histology / Q000378:metabolism; D014982:Xenopus laevis
D000199:Actins; D010590:Phalloidine; D011419:Propidium