title: Heart defects and ocular anomalies in children with Down's syndrome.
abstract: OBJECTIVE
  To investigate whether ocular anomalies are associated with congenital heart defects in children with Down's syndrome.
  
  
  METHODS
  58 children with Down's syndrome were entered into a retrospective observational study. Children were assigned to heart defect groups based on medical records. Optometric tests had previously been carried out at the homes of the children.
  
  
  RESULTS
  A relation between congenital cardiac defects, myopia, and nystagmus was observed. Heart problems were not related to accommodative insufficiency, hyperopia, or strabismus.
  
  
  CONCLUSIONS
  In children with Down's syndrome heart defects were associated with both myopia and nystagmus.
authors.affiliation: Department of Optometry and Vision Sciences, Cardiff University, UK. bromham@cf.ac.uk
authors.forename: N R
authors.initials: NR
authors.lastname: Bromham
authors.forename: J M
authors.initials: JM
authors.lastname: Woodhouse
authors.forename: M
authors.initials: M
authors.lastname: Cregg
authors.forename: E
authors.initials: E
authors.lastname: Webb
authors.forename: W I
authors.initials: WI
authors.lastname: Fraser
mesh_terms: D000065:Accommodation, Ocular; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004314:Down Syndrome / Q000150:complications*; D006330:Heart Defects, Congenital / Q000150:complications*; D006801:Humans; D006956:Hyperopia / Q000150:complications; D007223:Infant; D009216:Myopia / Q000150:complications*; D009759:Nystagmus, Pathologic / Q000150:complications*; D012189:Retrospective Studies; D013285:Strabismus / Q000150:complications