title: In vitro cell irradiation systems based on 210Po alpha source: construction and characterisation.
abstract: One way of studying the risk to human health of low-level radiation exposure is to make biological experiments on living cell cultures. Two 210Po alpha-particle emitting devices, with 0.5 and 100 MBq activity, were designed and constructed to perform such experiments irradiating monolayers of cells. Estimates of dose rate at the cell surface were obtained from measurements by a PIPS alpha-particle spectrometer and from calculations by the SRIM 2000, Monte Carlo charged particle transport code. Particle fluence area distributions were measured by solid state nuclear track detectors. The design and dosimetric characterisation of the devices are discussed.
authors.affiliation: KFKI Atomic Energy Research Institute, Budapest, Hungary. jszabo@sunserv.kfki.hu
authors.forename: J
authors.initials: J
authors.lastname: Szabo
authors.forename: I
authors.initials: I
authors.lastname: Feher
authors.forename: J
authors.initials: J
authors.lastname: Palfalvi
authors.forename: I
authors.initials: I
authors.lastname: Balashazy
authors.forename: A M
authors.initials: AM
authors.lastname: Dam
authors.forename: I
authors.initials: I
authors.lastname: Polonyi
authors.forename: E N
authors.initials: EN
authors.lastname: Bogdandi
mesh_terms: D000512:Alpha Particles; D002478:Cells, Cultured; D004735:Energy Transfer; D010315:Particle Accelerators / Q000295:instrumentation*; D011059:Polonium; D011853:Radiobiology / Q000295:instrumentation*; D011874:Radiometry
chemical_list: D011059:Polonium