Can eniluracil improve 5-fluorouracil therapy?
Diasio
Robert B
RB
Departments of Pharmacology/Toxicology and Medicine, Comprehensive Cancer Center, University of Alabama at Birmingham, USA.
D000964:Antimetabolites, Antineoplastic / Q000378:metabolism* / Q000627:therapeutic use; D042943:Dihydrouracil Dehydrogenase (NADP); D004357:Drug Synergism; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D005472:Fluorouracil / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D010088:Oxidoreductases / Q000502:physiology*; D014498:Uracil / Q000031:analogs & derivatives* / Q000627:therapeutic use*
D000964:Antimetabolites, Antineoplastic; D004791:Enzyme Inhibitors; C073482:eniluracil; D014498:Uracil; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil