[Changes in the level of short-chain volatile fatty acids and their aldehydes in oral air and fluid during inflammation of oral tissues].
It is shown that volatile short-chain fatty acids (propionate, butyrate and acetate) of bacterial and tissue origin are important factors of pathogenesis of oral tissue inflammation. A comparative biochemical study using chromato-mass-spectrometry, gas adsorptive and gas-liquid chromatography of oral media in healthy subjects has discovered that in gingivitis and parodontitis these media contain higher concentrations of short-chain fatty acids and lower ones of relevant aldehydes in intensification of the inflammatory process. The ratios of acetate/acetaldehyde, propionate/acrolein, butyrate/butyraldehyde increase considerably with intensification of parodontic inflammation making these values suitable for assessment of inflammation severity.
Petrovich
Iu A
IuA
Volozhin
A I
AI
Filatova
E S
ES
Fomina
O L
OL
D000085:Acetates / Q000032:analysis / Q000378:metabolism; D000328:Adult; D000388:Air / Q000032:analysis*; D000447:Aldehydes / Q000032:analysis / Q000378:metabolism*; D002087:Butyrates / Q000032:analysis / Q000378:metabolism; D005232:Fatty Acids, Volatile / Q000032:analysis / Q000378:metabolism*; D005410:Flame Ionization; D008401:Gas Chromatography-Mass Spectrometry; D005891:Gingivitis / Q000378:metabolism*; D006801:Humans; D010510:Periodontal Diseases / Q000378:metabolism*; D011422:Propionates / Q000032:analysis / Q000378:metabolism; D012463:Saliva / Q000378:metabolism
D000085:Acetates; D000447:Aldehydes; D002087:Butyrates; D005232:Fatty Acids, Volatile; D011422:Propionates