New onoceranoid triterpene constituents from Lansium domesticum.
Three new natural onoceranoid triterpenes, lansionic acid (1), 3beta-hydroxyonocera-8(26),14-dien-21-one (2), and 21alpha-hydroxyonocera-8(26),14-dien-3-one (3), were isolated from the fruit peel of Lansium domesticum together with two known triterpenoids (4 and 5), and their structures were elucidated from spectral data. These triterpenoids exhibited mild toxicity against brine shrimp (Artemia salina).
Tanaka
Tadamitsu
T
Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
Ishibashi
Masami
M
Fujimoto
Haruhiro
H
Okuyama
Emi
E
Koyano
Takashi
T
Kowithayakorn
Thaworn
T
Hayashi
Masahiko
M
Komiyama
Kanki
K
D000818:Animals; D001156:Artemia / Q000187:drug effects; D005638:Fruit / Q000737:chemistry; D029582:Meliaceae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013055:Spectrophotometry, Infrared; D013785:Thailand; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C471747:21alpha-hydroxyonocera-8(26),14-dien-3-one; C471746:3beta-hydroxyonocera-8(26),14-dien-21-one; D014315:Triterpenes; C471745:lansionic acid