Sakacin g, a new type of antilisterial bacteriocin.
Sakacin G is a 37-amino-acid-residue-long class IIa bacteriocin produced by Lactobacillus sake 2512, which is encoded by the duplicated structural genes skgA1 and skgA2. Sakacin G appears to be unique and seems to be an intermediate between pediocin-like bacteriocins, according to its double-disulfide bridges required for antimicrobial activity, and mesentericin-like bacteriocins in terms of sequence homologies, inhibition spectrum, and specific activity.
Simon
L
L
Laboratoire de Microbiologie Fondamentale et Appliquée, EA 2224, IBMIG, 86022 Poitiers, France.
Fremaux
C
C
Cenatiempo
Y
Y
Berjeaud
J M
JM
D000595:Amino Acid Sequence; D001430:Bacteriocins / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification*; D003001:Cloning, Molecular; D004220:Disulfides / Q000737:chemistry; D007778:Lactobacillus / Q000737:chemistry*; D008087:Listeria / Q000187:drug effects*; D008969:Molecular Sequence Data; D013329:Structure-Activity Relationship
D001430:Bacteriocins; D004220:Disulfides; C471065:sakacin G, Lactobacillus