Does coffee protect against hepatocellular carcinoma?
We analysed the relation between coffee consumption and hepatocellular carcinoma in two case-control studies conducted between 1984 and 1998 in Italy and Greece, including 834 cases and 1912 controls. Compared to non coffee drinkers, the multivariate odds ratio was 0.7 for drinkers of three or more cups per day.
Gallus
S
S
Istituto di Ricerche Farmacologiche Mario Negri, 20157 Milano, Italy. gallus@marionegri.it
Bertuzzi
M
M
Tavani
A
A
Bosetti
C
C
Negri
E
E
La Vecchia
C
C
Lagiou
P
P
Trichopoulos
D
D
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D016022:Case-Control Studies; D003069:Coffee / Q000009:adverse effects; D005260:Female; D006115:Greece / Q000453:epidemiology; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors
D003069:Coffee