title: Postherpetic ophthalmic neuralgia.
abstract: Postherpetic ophthalmic neuralgia is the final stage of a varicella zoster infection. Many years after chickenpox infection, patients can develop herpes zoster in one or more specific dermatomal regions. The ophthalmic branch of the trigeminal nerve and the thoracic nerves are most commonly affected. Younger patients are less prone to postherpetic neuralgia than the older. Patients with a depression in cell-mediated immunity are more susceptible to develop postherpetic pain. Postherpetic ophthalmic neuralgia is a neuropathic pain and can be treated by anticonvulsants and tricyclic antidepressants. Neurodestructive procedures are not recommended as they enhance destruction and neuropathic pain. Sympathetic nerve blocks can be helpful. Neurostimulation is the last therapeutic resort.
authors.affiliation: Ghent University Hospital, Department of Anesthesia-Section Pain Clinic, B-9000 Ghent, Belgium. jacques.devulder@rug.ac.be
authors.forename: J E R
authors.initials: JE
authors.lastname: Devulder
mesh_terms: D000779:Anesthetics, Local / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002644:Chickenpox / Q000150:complications*; D002648:Child; D006801:Humans; D008875:Middle Aged; D009882:Ophthalmic Nerve; D004561:Transcutaneous Electric Nerve Stimulation; D014277:Trigeminal Neuralgia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D000779:Anesthetics, Local; D000927:Anticonvulsants; D000929:Antidepressive Agents, Tricyclic