title: Nail manifestations in pemphigus vulgaris.
abstract: Nail involvement in pemphigus vulgaris is rare. We describe 5 patients with pemphigus vulgaris presenting nail involvement. In this disease, nail manifestations present, by order of frequency, as chronic paronychia, onychomadesis, onycholysis, Beau's lines and trachyonychia. All our 5 cases presented with paronychia, and 1 of them also had Beau's lines. Treatment with prednisone and/or cyclophosphamide controlled mucocutaneous and nail manifestations in all cases.
authors.affiliation: Department of Dermatology, Hospital das Clínicas, Faculty of Medicine, University of Sao Paulo, Brazil.
authors.forename: Juliana Burihan
authors.initials: JB
authors.lastname: Cahali
authors.forename: Everton Yuji Soyama
authors.initials: EY
authors.lastname: Kakuda
authors.forename: Cláudia Giuli
authors.initials: CG
authors.lastname: Santi
authors.forename: Celina Wakisaka
authors.initials: CW
authors.lastname: Maruta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D010392:Pemphigus / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone