Effects of solar simulated radiation on the human immune system: influence of phototypes and wavebands.
We have shown that skin-types I/II are much more susceptible to UVR-induced suppression of the induction phase of contact hypersensitivity than skin-types III/IV. Studies with a UVB sunscreen have provided indirect evidence that UVA is more immunosuppressive than it is erythemogenic. Overall, our studies show a lack of direct correlation between erythema and immunosuppression.
Young
Antony R
AR
Department of Environmental Dermatology, St John's Institute of Dermatology, Guy's, King's & St Thomas's School of Medicine, King's College London, St. Thomas's Hospital, Lambeth Palace Road, London SE1 7EH, UK.
Walker
Susan L
SL
D006801:Humans; D007107:Immune System / Q000528:radiation effects*; D013472:Sunlight / Q000009:adverse effects*; D014466:Ultraviolet Rays / Q000009:adverse effects