title: Peripheral nerve granuloma in a patient with tuberculosis.
abstract: The cause of peripheral neuropathy associated with tuberculosis is controversial. Possibilities include an immune mediated neuropathy, direct invasion of nerves, vasculitic neuropathy, compressive neuropathy, a meningitic reaction, and the toxic effects of antituberculous chemotherapy. This report describes the unusual finding of granulomas in the peripheral nerve of a patient with tuberculosis. The pathological findings were of a delayed hypersensitivity reaction, but with no more specific indications of the mechanism of the neuropathy.
authors.affiliation: University Department of Clinical Neurosciences, Royal Free and University College Medical School, University College London, London, UK. r.orrell@rfc.ucl.ac.uk
authors.forename: R W
authors.initials: RW
authors.lastname: Orrell
authors.forename: R H M
authors.initials: RH
authors.lastname: King
authors.forename: J V
authors.initials: JV
authors.lastname: Bowler
authors.forename: L
authors.initials: L
authors.lastname: Ginsberg
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009460:Neurologic Examination; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis* / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology; D014375:Tuberculoma / Q000175:diagnosis* / Q000473:pathology; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis / Q000473:pathology