title: Cine-MR Fourier phase imaging for quantification of regional wall asynergy in patients with anterior myocardial infarction.
abstract: OBJECTIVE
  The aim of this study was to evaluate whether Fourier analysis of cine-MR could detect wall motion abnormalities in patients with myocardial infarction.
  
  
  METHODS
  Ten patients with anterior myocardial infarction (seven men and three women; mean age, 58 +/- 16 years) were compared with six control subjects (four men and two women; mean age, 49 +/- 24 years). Gradient echo cardiac cine-MR slices were transformed using a commercially available Fourier algorithm to obtain phase angles of endocardial segments. Mean phase angle and phase dispersion (i.e., SD around the mean) were calculated. Segmental wall motion was evaluated using a 16-segment model and correlated to Fourier phase analysis.
  
  
  RESULTS
  Mean phase angle and phase dispersion were increased in patients compared with control subjects (respectively, 191 degrees +/- 23 degrees vs. 161 degrees +/- 25 degrees, P < 0.0001 and 21 degrees +/- 10 degrees vs. 11 degrees +/- 8 degrees, P = 0.0007). Analysis of variance showed a significant increased dispersion on basal slices (P = 0.002) mostly due to flow-void and entry slice phenomenon.
  
  
  CONCLUSIONS
  Fourier phase analysis of cardiac cine-MR is feasible and allows the evaluation of ventricular asynergy on the basis of endocardial wall motion.
authors.affiliation: Département de Médecine Nucléaire, Centre Henri Becquerel et CHU de Rouen, France. alain.manrique@rouen.fnclc.fr
authors.forename: Alain
authors.initials: A
authors.lastname: Manrique
authors.forename: Eric
authors.initials: E
authors.lastname: Tapon
authors.forename: Geneviève
authors.initials: G
authors.lastname: Derumeaux
authors.forename: Alain
authors.initials: A
authors.lastname: Cribier
authors.forename: Pierre
authors.initials: P
authors.lastname: Véra
authors.forename: Jean Nicolas
authors.initials: JN
authors.lastname: Dacher
mesh_terms: D005260:Female; D005583:Fourier Analysis; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis*