[Cerebral vasculitis].
This review focuses on isolated CNS-angiitis and cerebral involvement in systemic vasculitides and collagen vascular diseases. CNS-vasculitis presents with headache, multifocal symptoms, and encephalopathy, respectively. Clinical diagnosis is based on MRI, angiography and both CSF and serum examinations. But neither laboratory nor neuroradiological findings are specific - in all vasculitides with the exception of the Behçet-syndrome a biopsy is necessary before immunosuppressive treatment is started. Therapy of choice is the combination of corticosteroids and cyclophosphamide.
Berlit
P
P
Neurologische Klinik Alfried Krupp Krankenhaus Essen. peter.berlit@krupp-krankenhaus.de
Steinbrecher
A
A
D000477:Alkylating Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002536:Cerebral Arteries / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D013256:Steroids; D020293:Vasculitis, Central Nervous System / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology
D000477:Alkylating Agents; D000893:Anti-Inflammatory Agents; D013256:Steroids; D003520:Cyclophosphamide