Angiomyolipoma of the bladder.
Angiomyolipoma of the bladder is an extremely rare neoplasm. We report a case of a 55-year-old woman with an angiomyolipoma of the bladder visualized on pelvic sonogram as a 5 mm polyp in the floor of the bladder. The lesional tissue consisted of spindle cells, epithelioid cells, and adipocytes, with occasional thick-walled blood vessels. Immunohistochemical studies showed the spindle and epithelioid cells to be focally positive for HMB-45 and diffusely positive for actin and muscle cell antigen (HHF-35), which confirmed the diagnosis of angiomyolipoma. A review of the recent literature on the pathogenesis of angiomyolipoma follows.
Huan
Youming
Y
Departments of Pathology and Urology, Mount Sinai Medical Center, New York, NY 10029, USA.
Dillon
Robert W
RW
Unger
Pamela D
PD
D000199:Actins / Q000378:metabolism; D018207:Angiomyolipoma / Q000378:metabolism / Q000473:pathology*; D000951:Antigens, Neoplasm; D002277:Carcinoma / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D018230:Leiomyoma, Epithelioid / Q000473:pathology; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism; D012509:Sarcoma / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000378:metabolism / Q000473:pathology*
D000199:Actins; D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins