Accidental overdose of midazolam as intramuscular premedication.
We report two cases of overdoses of intramuscular midazolam used as a premedication. Both cases had no resedation or complications, but the accidents happened as a result of a resident and nurse's lack of experience with midazolam. The intramuscular doses, given at four times the normal quantity, fortunately caused no harm in our cases. However, the situations suggest that we should carefully check the dosage and review the correct procedures, even when using a drug that is considered to be familiar with most practitioners.
Nishiyama
Tomoki
T
Surgical Center, Institute of Medical Science, and Department of Anesthesiology, The University of Tokyo, Tokyo, Japan. nishi-tky@umim.ac.jp
Hanaoka
Kazuo
K
D000759:Adjuvants, Anesthesia / Q000009:adverse effects*; D000368:Aged; D062787:Drug Overdose; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008508:Medication Errors / Q000009:adverse effects*; D008874:Midazolam / Q000009:adverse effects*; D008875:Middle Aged; D011229:Preanesthetic Medication / Q000009:adverse effects*
D000759:Adjuvants, Anesthesia; D008874:Midazolam