title: Polymer-supported metal-phosphine complexes for use as catalysts or linkers in medicinally-oriented organic synthesis.
abstract: Polymer-supported catalysts and reagents have found many uses in synthetic organic chemistry. This review discusses the preparation of polymer-supported phosphine ligands and organometallic complexes formed using these and highlights their use in reactions that are of particular interest to medicinal chemists. The scope of the review is limited to phosphine ligands and their metal complexes attached to derivitised polystyrene supports.
authors.affiliation: Department of Chemistry, King's College London, Strand, London, WC2R 2LS, UK. nicholas.leadbeater@kcl.ac.uk
authors.forename: Nicholas E
authors.initials: NE
authors.lastname: Leadbeater
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003432:Cross-Linking Reagents; D019216:Metals, Heavy / Q000737:chemistry*; D009930:Organic Chemicals / Q000138:chemical synthesis*; D010720:Phosphines / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry
chemical_list: D003432:Cross-Linking Reagents; D019216:Metals, Heavy; D009930:Organic Chemicals; D010720:Phosphines; D011137:Polystyrenes