Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
The National Institutes of Health Mammalian Gene Collection (MGC) Program is a multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for each human and mouse gene. ESTs were generated from libraries enriched for full-length cDNAs and analyzed to identify candidate full-ORF clones, which then were sequenced to high accuracy. The MGC has currently sequenced and verified the full ORF for a nonredundant set of >9,000 human and >6,000 mouse genes. Candidate full-ORF clones for an additional 7,800 human and 3,500 mouse genes also have been identified. All MGC sequences and clones are available without restriction through public databases and clone distribution networks (see http:mgc.nci.nih.gov).
Strausberg
Robert L
RL
National Cancer Institute, Bethessda, MD 20892-2580, USA. rls@nih.gov
Feingold
Elise A
EA
Grouse
Lynette H
LH
Derge
Jeffery G
JG
Klausner
Richard D
RD
Collins
Francis S
FS
Wagner
Lukas
L
Shenmen
Carolyn M
CM
Schuler
Gregory D
GD
Altschul
Stephen F
SF
Zeeberg
Barry
B
Buetow
Kenneth H
KH
Schaefer
Carl F
CF
Bhat
Narayan K
NK
Hopkins
Ralph F
RF
Jordan
Heather
H
Moore
Troy
T
Max
Steve I
SI
Wang
Jun
J
Hsieh
Florence
F
Diatchenko
Luda
L
Marusina
Kate
K
Farmer
Andrew A
AA
Rubin
Gerald M
GM
Hong
Ling
L
Stapleton
Mark
M
Soares
M Bento
MB
Bonaldo
Maria F
MF
Casavant
Tom L
TL
Scheetz
Todd E
TE
Brownstein
Michael J
MJ
Usdin
Ted B
TB
Toshiyuki
Shiraki
S
Carninci
Piero
P
Prange
Christa
C
Raha
Sam S
SS
Loquellano
Naomi A
NA
Peters
Garrick J
GJ
Abramson
Rick D
RD
Mullahy
Sara J
SJ
Bosak
Stephanie A
SA
McEwan
Paul J
PJ
McKernan
Kevin J
KJ
Malek
Joel A
JA
Gunaratne
Preethi H
PH
Richards
Stephen
S
Worley
Kim C
KC
Hale
Sarah
S
Garcia
Angela M
AM
Gay
Laura J
LJ
Hulyk
Stephen W
SW
Villalon
Debbie K
DK
Muzny
Donna M
DM
Sodergren
Erica J
EJ
Lu
Xiuhua
X
Gibbs
Richard A
RA
Fahey
Jessica
J
Helton
Erin
E
Ketteman
Mark
M
Madan
Anuradha
A
Rodrigues
Stephanie
S
Sanchez
Amy
A
Whiting
Michelle
M
Madan
Anup
A
Young
Alice C
AC
Shevchenko
Yuriy
Y
Bouffard
Gerard G
GG
Blakesley
Robert W
RW
Touchman
Jeffrey W
JW
Green
Eric D
ED
Dickson
Mark C
MC
Rodriguez
Alex C
AC
Grimwood
Jane
J
Schmutz
Jeremy
J
Myers
Richard M
RM
Butterfield
Yaron S N
YS
Krzywinski
Martin I
MI
Skalska
Ursula
U
Smailus
Duane E
DE
Schnerch
Angelique
A
Schein
Jacqueline E
JE
Jones
Steven J M
SJ
Marra
Marco A
MA
D000465:Algorithms; D000818:Animals; D018076:DNA, Complementary / Q000032:analysis / Q000737:chemistry*; D015723:Gene Library; D006801:Humans; D051379:Mice; D016366:Open Reading Frames; D017422:Sequence Analysis, DNA
D018076:DNA, Complementary