[Frequency of Bordetella pertussis antibodies in serum of patients with Parkinson's disease].
The assessment of the levels of IgG antibodies against Bordetella pertussis in serum using ELISA test was performed in 59 patients (including 30 patients with Parkinson's disease--PD, 15 patients with other non-inflammatory neurological diseases, and 14 controls). The average age in the groups was 64.0, 64.4, and 58.7 years, respectively. Positive results were found in 17/30 patients with PD, 8/15 subjects with other non-inflammatory neurological diseases and in 7/14 controls. The above results are surprising and demonstrate a high incidence of subclinical whooping cough among the adult population. No statistically significant difference has been found between patients with Parkinson's disease and patients with other neurological diseases. A tendency is observed for a higher percentage of negative results among controls in comparison with patients with Parkinson's disease and other non-inflammatory neurological diseases.
Fiszer
Urszula
U
Klinika Neurologii i Epileptologii Centrum Medycznego Kształcenia Podyplomowego, w Warszawie.
Tomik
Bozena
B
Krygowska-Wajs
Anna
A
Michałowska
Małgorzata
M
Palasik
Witold
W
D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood*; D001886:Bordetella pertussis / Q000276:immunology*; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000276:immunology / Q000382:microbiology*; D014917:Whooping Cough / Q000175:diagnosis / Q000276:immunology*
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G