Analysis of cDNAs from a mouse embryo tooth library: identification of novel genes during tooth development.
Signaling molecules, their receptors, and target genes from pathways and networks regulate the development of the tooth from initiation through cell differentiation. In order to identify genes involved in odontoblast and ameloblast differentiation, we constructed a cDNA library from E19.5 mouse molars. In this work, we report the partial cDNA sequences of 10 noncharacterized genes and we show cell expression of the transcripts on mouse embryo molars by in situ hybridization.
Unda
F J
FJ
Department of Cell Biology, Faculty of Medicine and Dentistry, University of the Basque Country, Leioa 48940, Vizcaya, Spain. gcpunrof@ehu.es
Iehara
N
N
De Vega
S
S
De la Fuente
M
M
Vilaxa
A
A
Cobourne
M
M
Sharpe
P T
PT
Yamada
Y
Y
D000818:Animals; D018076:DNA, Complementary / Q000235:genetics* / Q000378:metabolism; D004622:Embryo, Mammalian / Q000378:metabolism; D015723:Gene Library; D051379:Mice / Q000196:embryology* / Q000235:genetics*; D008963:Molar / Q000196:embryology*; D009805:Odontogenesis / Q000235:genetics*; D012333:RNA, Messenger / Q000378:metabolism; D017386:Sequence Homology, Amino Acid
D018076:DNA, Complementary; D012333:RNA, Messenger