Hyaluronidase inhibitory activity from the polyphenols in the fruit of blackberry (Rubus fruticosus B.).
The hyaluronidase inhibitory activity of different fractions obtained from aqueous extract of blackberry fruits was evaluated. We found that only fractions F3 and F7 inhibit the tested enzyme.
Marquina
M A
MA
Grupo de Investigación en Cultivos Celulares, Laboratorio de Bioquímica, Facultad de Farmacia, Universidad de los Andes, Mérida 5101, Venezuela.
Corao
G M
GM
Araujo
L
L
Buitrago
D
D
Sosa
M
M
D004791:Enzyme Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids; D005638:Fruit / Q000737:chemistry*; D006821:Hyaluronoglucosaminidase / Q000037:antagonists & inhibitors*; D010636:Phenols / Q000302:isolation & purification* / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D011108:Polymers / Q000302:isolation & purification* / Q000494:pharmacology*; D059808:Polyphenols; D027824:Rosaceae / Q000737:chemistry*
D004791:Enzyme Inhibitors; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D011108:Polymers; D059808:Polyphenols; D006821:Hyaluronoglucosaminidase