Sheet structure of an L,D-dipeptide aggregate: inclusion compounds of (S)-phenylglycyl-(R)-phenylglycine with amides.
A simple dipeptide, (S)-phenylglycyl-(R)-phenylglycine (S,R-1), formed inclusion compounds with a small amide such as formamide, acetamide, N,N-dimethylformamide (DMF), or N,N-dimethylacetamide. By single-crystal X-ray analysis, the inclusion compounds were shown to have a wavy layer structure. The molecules of S,R-1 are arranged in parallel via ionic pairing of the carboxyl and amino groups to construct the wavy layers. The guest molecules were accommodated in a channel cavity between the layers by means of hydrogen bonding with (+)NH(3) of S,R-1. The cavity is surrounded by the phenyl groups of S,R-1 that conformationally rotate so as to make the cavity size fit the guest amide.
Akazome
Motohiro
M
Department of Materials Technology, Faculty of Engineering, Chiba University, 1-33 Yayoicho, Inageku, Japan.
Senda
Kyoko
K
Ogura
Katsuyuki
K
D000577:Amides / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004126:Dimethylformamide / Q000737:chemistry; D004151:Dipeptides / Q000737:chemistry*; D005998:Glycine / Q000031:analogs & derivatives / Q000737:chemistry*; D006860:Hydrogen Bonding; D046911:Macromolecular Substances; D008958:Models, Molecular; D015394:Molecular Structure; D011487:Protein Conformation; D013237:Stereoisomerism
D000577:Amides; D004151:Dipeptides; D046911:Macromolecular Substances; C473645:phenylglycyl-phenylglycine; D004126:Dimethylformamide; D005998:Glycine