Is the gastric epithelial barrier regulated by cadherin recruitment?
While still highly controversial, regulation of junctional structure remains an important feature in many physiological/pathological conditions. Mizuno et al. here report a mechanism in stomach epithelia where additional copies of cadherins appear to be recruited to the cell surface, apparently to maintain the solute barrier. This phenomenon may represent an important novel mechanism which epithelia may use to enhance barrier.
Alexander
J Steven
JS
Sasaki
Makoto
M
D015820:Cadherins / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D010539:Permeability
D015820:Cadherins