title: Studies on anti-diarrhoeal activity of Ficus hispida. Leaf extract in rats.
abstract: Methanol extract of Ficus hispida L. showed significant inhibitory activity against castor oil-induced diarrhoea and PGE(2)-induced enteropooling in rats. It also showed a significant reduction in gastro-intestinal motility on charcoal meal test in rats. The results obtained establish the F. hispida leaf extract as an anti-diarrhoeal agent.
authors.affiliation: Division of pharmacognosy, Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta 700 032 (WB), India. subhashmandal@yahoo.com
authors.forename: Subhash C
authors.initials: SC
authors.lastname: Mandal
authors.forename: C K
authors.initials: CK
authors.lastname: Ashok Kumar
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002368:Castor Oil; D003967:Diarrhea / Q000188:drug therapy*; D015232:Dinoprostone; D004305:Dose-Response Relationship, Drug; D005260:Female; D030681:Ficus / Q000737:chemistry*; D005769:Gastrointestinal Motility / Q000187:drug effects; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D018515:Plant Leaves / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D010936:Plant Extracts; D002368:Castor Oil; D015232:Dinoprostone