title: In vivo multiple spin echoes imaging of trabecular bone on a clinical 1.5 T MR scanner.
abstract: In vivo multiple spin echoes (MSE) images of bone marrow in trabecular bone were obtained for the first time on a clinical 1.5 T scanner. Despite of a reduced sensitivity of the MSE trabecular bone images with respect to the cerebral matter ones, it is possible to observe some features in the MSE trabecular bone images that may be useful in the diagnosis of osteopenic states. Two different CRAZED-type MSE imaging sequences based on spin-echo and EPI imaging modalities were applied in phantom and in vivo. Preliminary experimental results indicate that EPI imaging readout seems to conceal the MSE contrast correlated with pore dimension in porous media. However it is still possible to detect anisotropy effects related to the bone structure in MSE-EPI images. Some strategies are suggested to optimize the quality of MSE trabecular bone images.
authors.affiliation: Istituto Nazionale Fisica della Materia (INFM) UdR Roma1, E. Fermi Center and Physics Department University La Sapienza, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Capuani
authors.forename: G
authors.initials: G
authors.lastname: Hagberg
authors.forename: F
authors.initials: F
authors.lastname: Fasano
authors.forename: I
authors.initials: I
authors.lastname: Indovina
authors.forename: A
authors.initials: A
authors.lastname: Castriota-Scanderbeg
authors.forename: B
authors.initials: B
authors.lastname: Maraviglia
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000648:ultrastructure*; D017352:Echo-Planar Imaging / Q000295:instrumentation / Q000379:methods; D005260:Female; D005269:Femur / Q000033:anatomy & histology*; D006801:Humans; D008297:Male; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity