title: Fatal salmonella aortitis with mycotic aneurysm rupture.
abstract: Salmonellae most commonly cause uncomplicated cases of gastroenteritis but have a predilection for damaged blood vessels, especially those damaged by atherosclerosis. The abdominal aorta is most frequently affected. The most serious complication of aortitis is mycotic aneurysm formation with subsequent rupture. The authors present the case of a 61-year-old man who was found unresponsive at home 3 days after discharge from the hospital for treatment of gastroenteritis with bacteremia. Postmortem examination revealed a ruptured mycotic aneurysm with a large retroperitoneal hematoma. Numerous gram-negative rods were embedded in the wall of the aorta and surrounding inflammatory infiltrate, compatible with the patient's previously isolated. Whereas abdominal aortic aneurysm rupture is most commonly associated with atherosclerosis, the isolation of from blood cultures, coupled with radiographic evidence of gas surrounding the aorta, should raise the suspicion of infectious aortitis. Whereas fatal rupture of an aortic aneurysm secondary to atherosclerosis alone or in conjunction with aortitis will not have an impact on the manner of death, infections are reportable and thus have public health implications.
authors.affiliation: Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA. lsalzberger@aol.com
authors.forename: Lynn A
authors.initials: LA
authors.lastname: Salzberger
authors.forename: Dominick
authors.initials: D
authors.lastname: Cavuoti
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Barnard
mesh_terms: D000785:Aneurysm, Infected / Q000209:etiology* / Q000473:pathology; D017542:Aneurysm, Ruptured / Q000209:etiology* / Q000473:pathology; D001012:Aorta, Abdominal / Q000382:microbiology; D006406:Hematoma / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012187:Retroperitoneal Space / Q000382:microbiology; D012480:Salmonella Infections / Q000150:complications* / Q000473:pathology; D012477:Salmonella enteritidis