title: Complications of acute pancreatitis: clinical and CT evaluation.
abstract: Mortality of acute pancreatitis is dependent on the development of potentially lethal complications that can coexist and occur at any time following an acute attack. The nature and clinical relevance of these complications differ, contingent on the time of occurrence following a severe episode of pancreatitis. They can be divided into (1), early complications that manifest at the onset or within the first 2 to 3 days, (2) intermediate complications that occur predominantly during the second to fifth week, and (3) late complications that usually manifest months or years following the resolution of an acute attack. Early complications are systemic in nature with diverse clinical manifestations of the cardiovascular, pulmonary, renal, and/or metabolic systems. Intermediate complications are abdominal, pancreatic, and retroperitoneal, and are mostly septic in nature, associated with pancreatic or peripancreatic fat necrosis and pseudocysts. Late, life-threatening complications are mainly vascular or hemorrhagic in nature or involve the development of chronic pancreatic ascites. The early detection and objective evaluation of these complications by clinical and imaging methods leads to specific treatment options in the continuous attempt to decrease mortality rates in acute pancreatitis.
authors.affiliation: Radiology Department, New Bellevue Hospital, 3rd Floor, Room 3 W 37-3 W 42, 462 First Avenue, New York, NY 10016, USA. emiljmd@aol.com
authors.forename: Emil J
authors.initials: EJ
authors.lastname: Balthazar
mesh_terms: D000038:Abscess / Q000150:complications / Q000000981:diagnostic imaging; D000208:Acute Disease; D001201:Ascites / Q000000981:diagnostic imaging / Q000209:etiology; D005767:Gastrointestinal Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging; D010192:Pancreatic Pseudocyst / Q000150:complications / Q000000981:diagnostic imaging; D010195:Pancreatitis / Q000150:complications* / Q000000981:diagnostic imaging*; D019283:Pancreatitis, Acute Necrotizing / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed