[Endoscopic ultrasonography guided fine-needle aspiration in diagnosis of lung neoplasm and mediastinal lymph node metastasis].
OBJECTIVE
To access the feasibility, safety and accuracy of endoscopic ultrasonography guided fine-needle aspiration (EUS-FNA) in patients with suspected lung neoplasm and metastatic mediastinal lymph nodes.


METHODS
Using a linear array scanning endosonography (Pentax FG32-UA) and a 22-guage GIP (Medi-Globe) needle, we performed EUS-FNA in 10 patients including 6 patients with lung mass and enlarged mediastinal lymph nodes, 1 patient with a mass in the right lung, 1 patient with a mass near the esophagus, and 2 patients with extensive enlarged mediastinal lymph nodes. The data collected included lesions types, complications and diagnostic accuracy.


RESULTS
EUS-FNA revealed small cell carcinoma in 5 patients, squamous cell carcinoma in 1, adenocarcinoma in 1, and benign lymph nodes in 2. Malignancy was confirmed by follow-up in 7 patients, and benign tumor was confirmed by mediastinoscopy, thoracoscopy or follow-up in 2 patients. In 1 patient, FNA sample was not diagnosed because of inadequate specimen. None of the patients had complications caused by any procedures.


CONCLUSIONS
EUS-FNA is safe, reliable and accurate in diagnosis of suspicious lung neoplasm and mediastinal lymph node.
Wang
Jiandong
J
Department of Thoracic Surgery, General Hospital, People's Liberation Army, Beijing 100853, China.
Sun
Yu'e
Y
Wang
Zhiqiang
Z
Wang
Xiangdong
X
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D019160:Endosonography; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum; D008875:Middle Aged