title: Catatonia and ECT: Meduna's biological antagonism hypothesis reconsidered.
abstract: Catatonia is a motor syndrome with abnormalities in neuroendocrine regulation. Both the motor syndrome and the neuroendocrine abnormalities respond rapidly to electroconvulsive therapy (ECT). This rapid efficacy supports a neuroendocrine hypothesis of the mode of action of ECT and encourages neuroendocrine studies of catatonia.
authors.affiliation: Department of Psychiatry, School of Medicine, SUNY at Stony Brook, Albert Einstein College of Medicine, P.O. Box 457, St. James, New York 11780-0457, USA. mafink@attglobal.net
authors.forename: Max
authors.initials: M
authors.lastname: Fink
mesh_terms: D000654:Amobarbital / Q000494:pharmacology / Q000627:therapeutic use; D001921:Brain / Q000187:drug effects; D002389:Catatonia / Q000188:drug therapy / Q000628:therapy*; D004565:Electroconvulsive Therapy / Q000379:methods*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology / Q000627:therapeutic use; D009457:Neuroglia / Q000187:drug effects; D009490:Neurosecretory Systems / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D006993:Hypnotics and Sedatives; D005680:gamma-Aminobutyric Acid; D000654:Amobarbital