title: A radiopaque polymeric matrix for acrylic bone cements.
abstract: As part of the search for an alternative to inorganic radiopaque agents, this work studies the possibility of modifying bone cement formulations by incorporating a radiopaque monomer, that is, 4-iodophenol methacrylate (IPMA), in the liquid phase. The monomer was synthesized in the laboratory, and cements were prepared by the standard method. The influence on the different cement characteristics of various monomer concentrations was studied. It was seen that the setting time decreased as the percentage of monomer increased. The radiopacity attained in the 15 vol.% IPMA formulations was about the same as that for a cement containing 10 wt.% barium sulphate. Dynamic and static mechanical properties were measured. The materials did not show significant differences in the glass transition temperature. However, static mechanical properties showed enhanced compressive strength, tensile strength, and elastic modulus with respect to conventional cements formulated with barium sulphate. Histological studies showed a good response of muscular tissue to implanted specimens.
authors.affiliation: Dpto. Ciencia y Tecnología de Polímeros, POLYMAT (Institute of Polymeric Materials), Facultad de Química, Universidad del País Vasco, Apdo. 1072, 20080 San Sebastián, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Artola
authors.forename: I
authors.initials: I
authors.lastname: Goñi
authors.forename: J
authors.initials: J
authors.lastname: Gil
authors.forename: P
authors.initials: P
authors.lastname: Ginebra
authors.forename: J M
authors.initials: JM
authors.lastname: Manero
authors.forename: M
authors.initials: M
authors.lastname: Gurruchaga
mesh_terms: D001466:Barium Sulfate / Q000737:chemistry; D006358:Hot Temperature; D008420:Manufactured Materials; D008855:Microscopy, Electron, Scanning; D019904:Polymethyl Methacrylate / Q000138:chemical synthesis / Q000737:chemistry*; D013718:Tensile Strength
chemical_list: D001466:Barium Sulfate; D019904:Polymethyl Methacrylate