[Chronic radiation enteritis after irradiation of the lesser pelvis: surgical (im)possibilities].
Three women aged 74, 59 and 36 years, had chronic complaints of abdominal pain, nausea, vomiting and diarrhoea, 1 to 8 years after radiotherapy for pelvic malignancies. Mechanical ileus due to fibrotic adhesions was found to be the cause; all three patients recovered after one or more operations. The prevalence of chronic radiation injury correlates with both radiation factors (volume) and patient characteristics. If possible, tumour recurrence needs to be excluded. Chronic intermittent ileus is the predominant symptom of chronic radiation injury. It often occurs within 2 years, but sometimes as long as 10 to 20 years after radiotherapy. Resection is warranted when short segments are affected. In other cases an intestinal bypass or stoma is the treatment of choice.
Bloed
W
W
Afd. Heelkunde, Universitair Medisch Centrum, Postbus 85.500, 3508 GA Utrecht.
van Eijkeren
M A
MA
van Es
C A
CA
Borel Rinkes
I H M
IH
D000328:Adult; D000368:Aged; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology* / Q000601:surgery; D008875:Middle Aged; D010386:Pelvic Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000601:surgery*; D011878:Radiotherapy / Q000009:adverse effects*; D012086:Reoperation; D000267:Tissue Adhesions / Q000209:etiology / Q000601:surgery