Engulfment mechanism of apoptotic cells.
Apoptotic cells are engulfed and removed by phagocytes. This ensures proper development of the organism and can modulate immune responses. Recent studies have examined molecules on apoptotic cells, such as phosphatidylserine, which may signal for engulfment through multiple receptors. Apoptotic recognition mechanisms may vary with the apoptotic and engulfing cell type, and even with the age of the corpse.
Krieser
Ronald J
RJ
Cutaneous Biology Research Center, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA.
White
Kristin
K
D000818:Animals; D017209:Apoptosis; D008954:Models, Biological; D010586:Phagocytes / Q000502:physiology*; D010587:Phagocytosis; D011956:Receptors, Cell Surface / Q000502:physiology
D011956:Receptors, Cell Surface