title: [Application of continuous epidural analgesia with ropivacaine and fentanyl during delivery].
abstract: OBJECTIVE
  To evaluate the safety and efficiency of ropivacaine and fentanyl for continuous epidural analgesia during delivery.
  
  
  METHODS
  Altogether 98 full-term primigravidas with vertex presentation were selected for this study. Epidural catheter was placed during delivery with the cervical dilation of 3 cm, and the mixture of 0.2% ropivacaine and 2 microgram/ml fentanyl at the initial dose of 5 ml was given for continuous epidural analgesia. Drug infusion was discontinued when the second stage of delivery started. Another 98 primigravidas of similar conditions without analgesia served as the control group.
  
  
  RESULTS
  Analgesic group showed obvious pain-relieving effect (P<0.001) during the delivery, in which the active phase was significantly shortened (P<0.05). No obvious adverse effect arose in the mother and fetuses from the administration of analgesia.
  
  
  CONCLUSIONS
  Continuous epidural analgesia by pumping ropivacaine and fentanyl is effective and convenient for pain relief during delivery, and can be beneficial to the smooth progress of delivery.
authors.affiliation: Department of Gynecology and Obstetrics, First Affiliated Hospital of the Medical College of Ji'nan University, Guangzhou 510632, China.
authors.forename: Xiao-Qing
authors.initials: XQ
authors.lastname: Luo
authors.forename: Xue-Song
authors.initials: XS
authors.lastname: Gao
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Peng
authors.forename: Jin-Rong
authors.initials: JR
authors.lastname: Lin
mesh_terms: D000328:Adult; D000577:Amides; D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D036861:Delivery, Obstetric; D005260:Female; D005283:Fentanyl; D006801:Humans; D011247:Pregnancy; D000077212:Ropivacaine
chemical_list: D000577:Amides; D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D000077212:Ropivacaine; D005283:Fentanyl