Antimicrobial constituents from the rhizomes of Rheum emodi.
The bioassay-guided chemical examination of the rhizomes of R. emodi resulted in the isolation of two new oxanthrone esters, revandchinone-1, revandchinone-2, a new anthraquinone ether revandchinone-3 and a new oxanthrone ether, revandchinone-4. Their structures were established based on spectroscopic and degradative evidence. Occurrence of oxanthrone ether is reported for the first time. The anti bacterial and anti fungal activity of the isolates is studied.
Babu
K Suresh
KS
Natural Products Laboratory, Division of Organic Chemistry-I, Indian Institute of Chemical Technology, Hyderabad 500 007, India.
Srinivas
P V
PV
Praveen
B
B
Kishore
K Suresh
KS
Murty
U Suryanarayana
US
Rao
J Madhusudana
JM
D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004952:Esters / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004987:Ethers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D015394:Molecular Structure; D012250:Rheum / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry*
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D004952:Esters; D004987:Ethers; C473509:revandchinone-1; C473508:revandchinone-3