title: [Determination of tissue optical parameters using HF modulation spectroscopy].
abstract: Radio frequency modulation spectroscopy is a capable method to determine tissue optical parameters in-vivo. For the eventual purpose of clinical measurements we have developed and tested an rf laser spectroscopy device which enables a measurement of the spatial amplitude and phase shift profiles of backscattered modulated laser light. Spectral absorption and scattering coefficients are computed by inverse formulas derived from analytical solutions of the diffusion model of light transport in a semi-infinite geometry.
authors.affiliation: Institut für Biomedizinische Technik, Technische Universität Dresden, Deutschland. eckhard.schleicher@mailbox.tu-dresden.de
authors.forename: E
authors.initials: E
authors.lastname: Schleicher
authors.forename: U
authors.initials: U
authors.lastname: Hampel
authors.forename: M J
authors.initials: MJ
authors.lastname: Silva
authors.forename: R
authors.initials: R
authors.lastname: Freyer
mesh_terms: D006801:Humans; D010101:Oxygen Consumption / Q000502:physiology*; D019047:Phantoms, Imaging; D011846:Radio Waves; D012542:Scattering, Radiation; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation*; D013057:Spectrum Analysis / Q000295:instrumentation*; D014022:Tissue Survival / Q000502:physiology*