title: Chylothorax in Gorham's disease.
abstract: A 25-yr-old woman presented with a right pleural effusion. Destruction of 9th through 12th ribs, adjacent vertebral bodies, and transverse processes was noted on plain radiograph and a large low-attenuated, irregular shaped mass lesion with peripheral rim enhancement, destroying vertebral body and transverse process, was revealed on the computed tomographic scan. Magnetic resonance imaging showed high signal on T1- weighted image and iso- and low signal on T2-weighted image for the mass lesion replacing the vertebral bony cortex and marrow space. An open rib biopsy revealed the histopathological changes of Gorham's disease (essential osteolysis), even though only bloody fluid filling the empty space and rib and vertebral transverse process destruction were grossly observed on operation. Even though there was no definite response to radiotherapy and pleurodesis, the patient showed stable condition up to 20 months after diagnosis.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. heo1013@plaza.snu.ac.kr
authors.forename: Won Sup
authors.initials: WS
authors.lastname: Lee
authors.forename: Sung Han
authors.initials: SH
authors.lastname: Kim
authors.forename: Inho
authors.initials: I
authors.lastname: Kim
authors.forename: Hark Kyun
authors.initials: HK
authors.lastname: Kim
authors.forename: Keun Seok
authors.initials: KS
authors.lastname: Lee
authors.forename: Sang Yoon
authors.initials: SY
authors.lastname: Lee
authors.forename: Dae Seog
authors.initials: DS
authors.lastname: Heo
authors.forename: Bong-Soon
authors.initials: BS
authors.lastname: Jang
authors.forename: Yung-Jue
authors.initials: YJ
authors.lastname: Bang
authors.forename: Noe Kyeong
authors.initials: NK
authors.lastname: Kim
mesh_terms: D000328:Adult; D002916:Chylothorax / Q000150:complications / Q000473:pathology* / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D010015:Osteolysis, Essential / Q000150:complications / Q000473:pathology* / Q000532:radiotherapy*; D018700:Pleurodesis; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome