title: The assessment of IgG avidity in the evaluation of perinatal herpes simplex virus infection.
abstract: Classical serologic assays are not useful for the diagnosis of perinatal herpes simplex virus (HSV) infection during the acute phase of the disease. We report two cases of neonatal HSV infection that highlight the diagnostic value of HSV-specific IgG avidity and its contribution for further characterization of neonatal HSV infection.
authors.affiliation: Service de Pédiatrie et Réanimation Néonatales, Hôpital Antoine-Béclère, Assistance Publique/Hôpitaux de Paris, Clamart, France.
authors.forename: Marie-Hélène
authors.initials: MH
authors.lastname: Odièvre
authors.forename: Denis
authors.initials: D
authors.lastname: Cointe
authors.forename: Bernard
authors.initials: B
authors.lastname: Thébaud
authors.forename: Véronique
authors.initials: V
authors.lastname: Zupan
authors.forename: Didier
authors.initials: D
authors.lastname: Ingrand
authors.forename: Thierry
authors.initials: T
authors.lastname: Lacaze-Masmonteil
authors.forename: Liliane
authors.initials: L
authors.lastname: Grangeot-Keros
mesh_terms: D000915:Antibody Affinity / Q000502:physiology*; D005260:Female; D006561:Herpes Simplex / Q000097:blood* / Q000503:physiopathology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000502:physiology*; D007231:Infant, Newborn; D008297:Male; D018139:Simplexvirus / Q000302:isolation & purification / Q000502:physiology*
chemical_list: D007074:Immunoglobulin G