[Model construction for reperfusion of the isolated pig liver].
In recent years thermal ablation of liver tumors as a minimally invasive method became a promising alternative to conventional strategies such as chemotherapy or resection of liver tissue. Thereby an electrode is placed inside the tumor delivering energy in the form of high frequency current into the target volume to achieve and maintain a tissue temperature between 60 and 100 degrees C. Cells exposed to this thermic stress undergo coagulation necrosis and are irreversibly damaged. To protect vital liver structures from heat, it is necessary to develop an online temperature monitoring system. An experimental setup perfusing isolated pig livers under physiological conditions with 0.9% NaCl solution was established to develop and evaluate the measuring technique.
Welp
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C
Lehrstuhl für Biomedizinische Technik, Medizinische Fakultät, Ruhr-Universität Bochum. welp@biomed.ruhr-uni-bochum.de
Siebers
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Zapletal
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Ermert
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Bechstein
W O
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Werner
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D000818:Animals; D006979:Hyperthermia, Induced / Q000295:instrumentation*; D066298:In Vitro Techniques; D008099:Liver / Q000473:pathology / Q000503:physiopathology*; D009862:Online Systems / Q000295:instrumentation*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D013552:Swine; D013821:Thermometers