Slit proteins, potential endogenous modulators of inflammation.
Recent studies suggest that molecules important for guiding neuronal migration and axon path-finding also play a role in modulating leukocyte chemotaxis. Neuronal migration and leukocyte chemotaxis may share some common regulatory mechanisms. Intracellular signal transduction mechanisms guiding neuronal migration and leukocyte chemotaxis are beginning to be elucidated. Studying molecular mechanisms modulating cell migration may provide new insights into understanding of endogenous inhibitors of inflammation.
Havlioglu
Necat
N
Departments of Pediatrics and Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Missouri, USA.
Yuan
Liya
L
Tang
Hao
H
Wu
Jane Y
JY
D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D018836:Inflammation Mediators / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000276:immunology*; D015213:Neuroimmunomodulation / Q000502:physiology*; D009474:Neurons / Q000276:immunology*
D006023:Glycoproteins; D018836:Inflammation Mediators; D009419:Nerve Tissue Proteins; C120566:slit protein, vertebrate