title: [Spontaneous abortions of first trimester pregnancy: is uterine aspiration still in line?].
abstract: Spontaneous abortions of first trimester pregnancy is a frequent pathology in gynecology (more than 10% of clinical pregnancy). Since the mid of twentieth century, the gold standard of evacuation of spontaneous abortion is manual vacuum aspiration most of the time under general anesthesia. This method is used in France for all miscarriages after 7 weeks' gestation at the sonography (about 40,000 women in 1999) but complications are not rare. The vaginal sonography and new medical management changes the view. We can now use expectative management or medical management with misoprostol and/or mifepristone. We summarise the current literature and propose a randomised multicentric control trial.
authors.affiliation: Département de gynécologie obstétrique et médecine faetale, CHU Hôtel-Dieu, 4, rue Larrey, 49033 Angers, France. loicdeponcheville@chu-angers.fr
authors.forename: L
authors.initials: L
authors.lastname: de Poncheville
authors.forename: H
authors.initials: H
authors.lastname: Marret
authors.forename: F
authors.initials: F
authors.lastname: Perrotin
authors.forename: J
authors.initials: J
authors.lastname: Lansac
authors.forename: G
authors.initials: G
authors.lastname: Body
mesh_terms: D000019:Abortifacient Agents / Q000627:therapeutic use; D000022:Abortion, Spontaneous / Q000628:therapy*; D005260:Female; D006801:Humans; D015735:Mifepristone / Q000627:therapeutic use; D016595:Misoprostol / Q000627:therapeutic use; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011453:Prostaglandins / Q000627:therapeutic use; D014620:Vacuum Extraction, Obstetrical / Q000009:adverse effects
chemical_list: D000019:Abortifacient Agents; D011453:Prostaglandins; D016595:Misoprostol; D015735:Mifepristone