title: Diffusion-weighted half-Fourier single-shot turbo spin echo imaging in breast tumors: differentiation of invasive ductal carcinoma from fibroadenoma.
abstract: OBJECTIVE
  The purpose of this investigation is to evaluate the usefulness of diffusion-weighted half-Fourier single-shot turbo spin echo (DW-HASTE) imaging in differentiating invasive ductal carcinoma from fibroadenoma.
  
  
  METHODS
  The DW-HASTE imaging was performed in patients with invasive ductal carcinoma (n = 16) and fibroadenoma (n = 6). Images were obtained with diffusion-sensitizing gradients of 0 and 700 mm(2)/s. The apparent diffusion coefficient (ADC) was calculated.
  
  
  RESULTS
  The DW-HASTE imaging was not affected with susceptibility and chemical shift artifacts usually present in DW echo planar imaging. The DW-HASTE imaging had low tumor detectability (62%), however. The difference in mean ADC of invasive ductal carcinoma (1.216 +/- 0.189 x 10(-3)mm(2)/s) and fibroadenoma (1.495 +/- 0.181 x 10(-3)mm(2)/s) was statistically significant.
  
  
  CONCLUSIONS
  Apparent diffusion coefficient measurement using DW-HASTE imaging is helpful in differentiating invasive ductal carcinoma from fibroadenoma. Nevertheless, DW-HASTE imaging has low detectability at present; therefore, more technologic improvement is desired.
authors.affiliation: Department of Radiology, Kameda Medical Center, Chiba, Japan. t_kino@kb3.so-net.ne.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kinoshita
authors.forename: Naobumi
authors.initials: N
authors.lastname: Yashiro
authors.forename: Nobumaro
authors.initials: N
authors.lastname: Ihara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Funatu
authors.forename: Eisuke
authors.initials: E
authors.lastname: Fukuma
authors.forename: Makoto
authors.initials: M
authors.lastname: Narita
mesh_terms: D000328:Adult; D000368:Aged; D016477:Artifacts; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis / Q000473:pathology*; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged