title: [A comparative clinico-pharmacological study of adalat, foridone, siskor, lomir effects on cerebral and peripheral circulation in patients with arterial hypertension].
abstract: The results of a comparative clinicopharmacological study of adalate, foridone, siskor and lomir effects on cerebral and peripheral blood flow are presented for 46 patients with arterial hypertension stage I-III. It was found that all the four drugs relieve tonicity and enhance blood flow in a. cerebri media and a. carotis communis. Lomir and adalate had more potent effects on central hemodynamics. A maximal dilating effect on regional peripheral arteries was observed after a single intake of siskor and adalate, while lomir's and foridone's single doses were weaker. In course treatment with the above drugs these differences are less.
authors.forename: L I
authors.initials: LI
authors.lastname: Svetyĭ
authors.forename: S N
authors.initials: SN
authors.lastname: Alekhin
authors.forename: L I
authors.initials: LI
authors.lastname: Pavlova
authors.forename: R S
authors.initials: RS
authors.lastname: Kuchumov
mesh_terms: D001775:Blood Circulation / Q000187:drug effects*; D002121:Calcium Channel Blockers / Q000494:pharmacology* / Q000627:therapeutic use*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
chemical_list: D002121:Calcium Channel Blockers