Prevalence monitoring in syphilis surveillance: results from a multicenter research program.
BACKGROUND
Syphilis seroprevalence data can be used as an independent measure of syphilis trends and to augment syphilis case report data for program planning. The prevalence of reactive syphilis serology in jails, delivery rooms, and drug treatment centers was examined from 1995 to 1999. Prevalence was evaluated by age and gender at each site and compared with county primary and secondary syphilis case rates. Annual prevalence of high titer-reactive serology in jails was compared with primary and secondary syphilis case rates.


OBJECTIVE
The goal was to examine trends in syphilis seroprevalence and to evaluate the relationship of trends in seroprevalence to reported cases.


METHODS
This was a cross-sectional survey.


RESULTS
Prevalence of reactive serology and high titer-reactive serology was lowest among women in delivery rooms (2.9% and 0.4%, respectively) and highest among women in jails (11.1% and 4.1%, respectively), indicating substantial recently treated or active infection among women in jails. Trends in high titer-reactive serology were similar to primary and secondary syphilis case rates.


CONCLUSIONS
The prevalence of high titer-reactive serology can provide valuable information about community syphilis morbidity for use in prevention and control programs.
Finelli
Lyn
L
Epidemiology Branch, Division of Viral Hepatitis, National Center for Infectious Diseases, MS G-37, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA.
Farley
Thomas P
TP
Gibson
James J
JJ
Langley
Carol
C
Hwang
Lu-Yu
LY
Levine
William C
WC
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods; D011330:Prisons; D016036:Seroepidemiologic Studies; D017678:Sex Distribution; D013587:Syphilis / Q000097:blood / Q000453:epidemiology* / Q000517:prevention & control*; D013781:Texas / Q000453:epidemiology