A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host.
Bom
Anton
A
Department of Medicinal Chemistry, Newhouse ML1 5SH, Scotland, UK.
Bradley
Mark
M
Cameron
Ken
K
Clark
John K
JK
Van Egmond
Jan
J
Feilden
Helen
H
MacLean
Elizabeth J
EJ
Muir
Alan W
AW
Palin
Ronald
R
Rees
David C
DC
Zhang
Ming-Qiang
MQ
D000732:Androstanols / Q000737:chemistry* / Q000494:pharmacology; D000818:Animals; D018360:Crystallography, X-Ray; D003505:Cyclodextrins / Q000737:chemistry* / Q000494:pharmacology; D003964:Diaphragm / Q000187:drug effects / Q000294:innervation; D066298:In Vitro Techniques; D008253:Macaca mulatta; D051379:Mice; D008958:Models, Molecular; D009119:Muscle Contraction / Q000187:drug effects; D019148:Neuromuscular Blockade; D003473:Neuromuscular Nondepolarizing Agents / Q000737:chemistry* / Q000494:pharmacology; D000077123:Rocuronium; D000077122:Sugammadex; D047408:gamma-Cyclodextrins
D000732:Androstanols; D003505:Cyclodextrins; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium