First bite.
Dipeptidyl peptidase IV contributes to the regulation of many physiological processes, most notably blood sugar homeostasis, by biting a dipeptide off the N terminus of specific peptides. A structure of this peptidase in complex with an inhibitor will assist efforts to regulate this regulator.
Gorrell
Mark D
MD
D001665:Binding Sites; D002384:Catalysis; D020134:Catalytic Domain; D019281:Dimerization; D018819:Dipeptidyl Peptidase 4 / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship
D018819:Dipeptidyl Peptidase 4