Cavernous sinus involvement by extramedullary plasmacytoma of the sphenoid sinus. An argument for the use of adjuvant chemotherapy.
A 63-year-old man with cavernous sinus involvement from extramedullary plasmacytoma (EMP) of the sphenoid sinus is described. Transient resolution of retro-orbital headache and continued progression of the locally extensive tumor were noted after chemotherapy was given following a poor response to 5400 cGy of local irradiation. To determine whether adjunctive chemotherapy will improve the outcome of these particular patients, we propose that a randomized trial comparing radiotherapy to chemoradiation be conducted.
Ampil
Federico L
FL
Division of Radiation Oncology, Department of Radiology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA.
Borski
T Greg
TG
Nathan
Cherie Ann O
CO
Mulcahy
Gregory
G
Walker
Michael
M
Chin
Hong W
HW
Stucker
Fred J
FJ
D000368:Aged; D002426:Cavernous Sinus / Q000473:pathology*; D017024:Chemotherapy, Adjuvant; D004172:Diplopia; D006261:Headache; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000628:therapy*; D010954:Plasmacytoma / Q000175:diagnosis / Q000628:therapy*; D013812:Therapeutics