title: Steroid receptors in various glial cell lines expression and functional studies.
abstract: In glial cell lines from the central (CG4, C6) and peripheral (MSC80, CR3a1, and CR1b4) nervous systems, glucocorticoid receptor (GR) messenger RNA was clearly detected and was consistent with significant GR binding and transcriptional activity. Mineralocorticosteroid receptor mRNA was less abundant, with no corresponding binding and lack of transcriptional activity. Other steroid receptors were not significantly detected.
authors.affiliation: INSERM U488, 80 rue du Général Leclerc, 94276 Le Kremlin-Bicêtre, France. cadepond@kb.inserm.fr
authors.forename: Francoise
authors.initials: F
authors.lastname: Cadepond
authors.forename: Charbel
authors.initials: C
authors.lastname: Massaad
authors.forename: Amalia
authors.initials: A
authors.lastname: Trousson
authors.forename: Julien
authors.initials: J
authors.lastname: Grenier
authors.forename: Ghislaine
authors.initials: G
authors.lastname: Groyer
authors.forename: Etienne
authors.initials: E
authors.lastname: Baulieu
authors.forename: Michael
authors.initials: M
authors.lastname: Schumacher
mesh_terms: D000818:Animals; D002460:Cell Line; D009457:Neuroglia; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D011965:Receptors, Glucocorticoid / Q000235:genetics* / Q000502:physiology; D014158:Transcription, Genetic / Q000187:drug effects / Q000502:physiology*; D014407:Tumor Cells, Cultured
chemical_list: D012333:RNA, Messenger; D011965:Receptors, Glucocorticoid