Caroli's disease - a report of two siblings.
A 26-year-old man had suffered from several episodes of right upper-quadrant pain for 6 months. Abdominal ultrasonography showed multiple saccular dilatations of the intrahepatic biliary tract, with hepatolithiasis at the bilateral hepatic lobe. Abdominal computed tomography also revealed saccularly dilated intrahepatic ducts with hepatolithiasis. Communication between saccular dilatations of the intrahepatic biliary tract and normal bile ducts was demonstrated by endoscopic retrograde cholangiopancreatography. Choledochal cyst type V (Caroli's disease) was diagnosed. The patient's 29-year-old sister was also diagnosed with Caroli's disease based on abdominal sonography. An ultrasonography survey was carried out on the family. Reports of Caroli's disease occurring in two siblings are rare in the literature.
Wu
Keng-Liang
KL
Division of Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Changchien
Chi-Sin
CS
Kuo
Chung-Mou
CM
Chuah
Seng-Kee
SK
Chiu
Yi-Chun
YC
Kuo
Chung-Huang
CH
D000328:Adult; D016767:Caroli Disease / Q000175:diagnosis / Q000235:genetics*; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree; D014057:Tomography, X-Ray Computed / Q000379:methods