title: [Free radical processes and their role in pathogenesis of some gastrointestinal diseases (part 1)].
abstract: The authors studied enzymatic and non-enzymatic modes of active oxygen forms formation, mechanisms of their damage to live cells, in particular, initiation of free radical lipid peroxidation; investigated anti- and prooxidant systems of body defense responsible for balance between appearance, metabolism and utilization of active oxygen forms. Impairment of this balance converts physiological processes into pathological ones. Peculiarities of free radical processes and their role in pathogenesis of some gastrointestinal diseases are described.
authors.forename: M B
authors.initials: MB
authors.lastname: Khutsishvili
authors.forename: S I
authors.initials: SI
authors.lastname: Rapoport
mesh_terms: D000818:Animals; D019069:Cell Respiration / Q000502:physiology; D005609:Free Radicals / Q000378:metabolism; D005764:Gastroesophageal Reflux / Q000209:etiology / Q000378:metabolism*; D005767:Gastrointestinal Diseases / Q000209:etiology / Q000378:metabolism*; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology; D018384:Oxidative Stress / Q000502:physiology; D017382:Reactive Oxygen Species / Q000378:metabolism*
chemical_list: D005609:Free Radicals; D017382:Reactive Oxygen Species