title: Massive subdural haematomas in Menkes disease mimicking shaken baby syndrome.
abstract: BACKGROUND
  Menkes disease is an X-linked inherited disorder of intestinal copper absorption resulting in copper deficiency. Cardinal features include hair abnormalities, facial dysmorphism, severe neurological impairment, hypothermia, arterial anomalies, bone abnormalities and a fatal outcome.
  
  
  METHODS
  We present a case of Menkes disease complicated by progressive macrocephaly following the development of massive subdural haematomas. These lesions associated with femoral metaphyseal spurs could be confused with nonaccidental injury such as that seen in the shaken baby syndrome.
  
  
  CONCLUSIONS
  This case emphasises that Menkes disease, like glutaric aciduria type 1, should be included in the differential diagnosis of unexplained subdural haematomas and neurological deficits in infants.
authors.affiliation: Service de Neurologie Pédiatrique, Cliniques Universitaires Saint-Luc, Avenue Hippocrate 10/1062, 1200 Brussels, Belgium. marie-cecile.nassogne@nepe.ucl.ac.be
authors.forename: Marie-Cécile
authors.initials: MC
authors.lastname: Nassogne
authors.forename: Mark
authors.initials: M
authors.lastname: Sharrard
authors.forename: Lucie
authors.initials: L
authors.lastname: Hertz-Pannier
authors.forename: Didier
authors.initials: D
authors.lastname: Armengaud
authors.forename: Guy
authors.initials: G
authors.lastname: Touati
authors.forename: Pascale
authors.initials: P
authors.lastname: Delonlay-Debeney
authors.forename: Michel
authors.initials: M
authors.lastname: Zerah
authors.forename: Francis
authors.initials: F
authors.lastname: Brunelle
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Saudubray
mesh_terms: D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005269:Femur / Q000002:abnormalities / Q000000981:diagnostic imaging; D006197:Hair / Q000002:abnormalities; D006408:Hematoma, Subdural / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007223:Infant; D008297:Male; D007706:Menkes Kinky Hair Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000235:genetics; D011859:Radiography; D038642:Shaken Baby Syndrome / Q000175:diagnosis*; D015898:Tomography Scanners, X-Ray Computed