title: Turicella otitidis and Corynebacterium auris do not cause otitis media with effusion in children.
abstract: BACKGROUND
  The recently described coryneform bacteria and were first detected in the middle ear of patients with acute otitis media and chronic otitis media. Whether these bacteria play an essential role in the pathogenesis of otitis media with effusion (OME) is unclear.
  
  
  METHODS
  In a prospective study 60 children with OME and 205 controls were evaluated to determine the incidence of and. Swabs from the external auditory canal (EAC) and the middle ear effusion (MEE) of OME children undergoing tympanotomy, ventilation tube insertion or both were cultured. Swabs from the EAC from healthy children served as controls.
  
  
  RESULTS
  In control children was found in EAC swabs from 23 of 205 (11.2%) and in 32 of 205 (15.6%). was isolated from 14 of 60 (23.3%) OME patients from the EAC only and in 6 of 60 (10.0%) OME patients from both EAC and MEE. was isolated in 2 of 60 (3.3%) from the EAC only and in 1 of 60 (1.7%) from both EAC and MEE. In no patient did or grow exclusively from MEE.
  
  
  CONCLUSIONS
  and may be part of the normal bacterial flora of the EAC in some children. Neither organism seems to cause OME in children.
authors.affiliation: Department of Otorhinolaryngology, University of Zurich, Switzerland. holzmann@orl.usz.ch
authors.forename: David
authors.initials: D
authors.lastname: Holzmann
authors.forename: Guido
authors.initials: G
authors.lastname: Funke
authors.forename: Thomas
authors.initials: T
authors.lastname: Linder
authors.forename: David
authors.initials: D
authors.lastname: Nadal
mesh_terms: D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003352:Corynebacterium / Q000145:classification* / Q000302:isolation & purification; D003354:Corynebacterium Infections / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D004352:Drug Resistance, Microbial; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D008876:Middle Ear Ventilation; D010034:Otitis Media with Effusion / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology* / Q000628:therapy; D011336:Probability; D011446:Prospective Studies; D012016:Reference Values; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D017678:Sex Distribution
chemical_list: D000900:Anti-Bacterial Agents