Translocation of Broca's area to the contralateral hemisphere as the result of the growth of a left inferior frontal glioma.
We report a case of a patient with a left inferior frontal glioma in whom language functional magnetic resonance imaging (fMRI) paradigms produced activation of Broca's area on the right and Wernicke's area on the left. We propose that tumor invasion of the left frontal operculum led to cortical reorganization and interhemispheric transfer of Broca's area. This case emphasizes the importance of preoperative fMRI in assessing the location of eloquent cortices adjacent to a tumor and in guiding neurosurgical decision-making.
Holodny
Andrei I
AI
Department of Radiology, University of Medicine and Dentistry of New Jersey-NJ Medical School, Newark, NJ, USA. holodnya@mskcc.org
Schulder
Michael
M
Ybasco
Albert
A
Liu
Wen-Ching
WC
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications* / Q000601:surgery; D003657:Decision Making; D005625:Frontal Lobe / Q000002:abnormalities / Q000502:physiology*; D007839:Functional Laterality; D005910:Glioma / Q000150:complications* / Q000601:surgery; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures; D011183:Postoperative Complications / Q000517:prevention & control*; D013702:Temporal Lobe / Q000002:abnormalities / Q000502:physiology*