title: [Effects of Seroxat on premature ejaculation: a clinical trial].
abstract: OBJECTIVE
  To evaluate the effects of antidepressant Seroxat on premature ejaculation.
  
  
  METHODS
  After having taken Seroxat 20 mg every noon for four weeks, the patients were asked to fill the investigating questionaire about the effects and side effects before and after the treatment.
  
  
  RESULTS
  After the treatment, 43 cases in our study had increased their ejaculation latency time, enhanced the quality of their sexy lives and their wives', and had significant difference compared with pre-treatment(P < 0.001). They had good effects on improving premature ejaculation after taking Seroxat (11.26 +/- 5.79) days; and after having stopped taking seroxat for (20.94 +/- 8.04) days, the situation of premature ejaculation in 32 cases were as same as that of before. There were seven cases whose sexuality and oomph increased, and two cases whose sexuality were decreased. A few patients had constipation, dry in mouth, insomnia and itch in skin, after taking the drugs.
  
  
  CONCLUSIONS
  Antidepressant Seroxat has rather good effects on premature ejaculation and should be used and studied further.
authors.affiliation: Department of Andrology and Urology, First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510405, China. yongchaoqiu@163.net
authors.forename: Yong-Chao
authors.initials: YC
authors.lastname: Qiu
authors.forename: Xi-Kun
authors.initials: XK
authors.lastname: Wang
authors.forename: Zhi-Bin
authors.initials: ZB
authors.lastname: Cui
authors.forename: Shao-Hui
authors.initials: SH
authors.lastname: Lin
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004542:Ejaculation / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D017374:Paroxetine / Q000009:adverse effects / Q000627:therapeutic use*; D012735:Sexual Dysfunction, Physiological / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D017374:Paroxetine