title: [A case report of hepatocellular carcinoma with portal thrombus responding to hepatic arterial infusion chemo-lipiodolization].
abstract: A 73-year old man with multiple hepatocellular carcinomas underwent 4 transarterial chemoembolizations, but a tumor thrombus appeared in the left portal vein. The tumor sizes in segments 4 and 5 were 4.0 cm and 2.4 cm, respectively. The serum levels of AFP and PIVKA-II were 14,991 ng/ml and 15,944 mAU/ml, respectively. The tumor was 5-FU palpable in the epigastric region. Four ml of SMANCS and 4 ml of Lipiodol were injected to proper hepatic artery using the Seldinger technique. In addition, epirubicin (20 mg), MMC (4 mg) and Lipiodoi (2 ml) were injected into a proper hepatic artery via a reservoir every 3 weeks. The tumor was not palpable, and the tumor markers were markedly reduced after 2 months. The evaluation of response to the treatment was a partial response 3 months and 6 months later. Chemo-lipiodolization was very useful for advanced hepatocellular carcinoma with portal vein thrombus.
authors.affiliation: Dept. of Surgery, Sakai Municipal Hospital.
authors.forename: Seizo
authors.initials: S
authors.lastname: Masutani
authors.forename: Junzo
authors.initials: J
authors.lastname: Shimizu
authors.forename: Masayuki
authors.initials: M
authors.lastname: Tatsuta
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Katoh
authors.forename: Kotaro
authors.initials: K
authors.lastname: Kitani
authors.forename: Kouji
authors.initials: K
authors.lastname: Esumi
authors.forename: Norikazu
authors.initials: N
authors.lastname: Masuda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imamura
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ishida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furukawa
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Onishi
authors.forename: Kyo
authors.initials: K
authors.lastname: Tsuda
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Inoue
authors.forename: Kouichi
authors.initials: K
authors.lastname: Tomotsu
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Usui
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D015251:Epirubicin / Q000008:administration & dosage; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage*; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage; D009364:Neoplasm Recurrence, Local; D011169:Portal Vein; D013927:Thrombosis / Q000150:complications*
chemical_list: D015251:Epirubicin; D016685:Mitomycin; D007459:Iodized Oil