title: [Pre-menopausal simple hysterectomy and post-menopausal female bone mineral density].
abstract: This study aimed to evaluate the bone mineral density (BMD) of post-menopausal women with previous pre-menopausal hysterectomy including bilateral ovarian conservation compared to a group of non-hysterectomized women with natural menopause. Data from a cross-sectional study of 30 pre-menopausally hysterectomized women evaluated in the post-menopause were compared with 102 naturally post-menopausal women, analyzing their respective bone densitometry, measuring the femoral and lumbar spinal BMD. Multiple regression analysis of the 132 women showed that age and body mass index (BMI) were heavily associated with femoral and lumbar spinal BMD, BMI directly associated, and age inversely associated with BMD. In addition, 30 hysterectomized women were matched by age and BMI to the 30 non-hysterectomized women, and bone densitometry did not show significant differences in BMD. These findings suggest that pre-menopausal hysterectomy with bilateral ovarian conservation does not appear to cause an additional reduction in bone mass when evaluated in the post-menopausal phase.
authors.affiliation: Departamento de Tocoginecologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP 13083-970, Brasil. jhobeika@cosmo.com.br
authors.forename: João Daniel
authors.initials: JD
authors.lastname: Hobeika
authors.forename: Aarão Mendes Pinto
authors.initials: AM
authors.lastname: Neto
authors.forename: Lúcia Helena Simões da Costa
authors.initials: LH
authors.lastname: Paiva
authors.forename: Adriana Orcesi
authors.initials: AO
authors.lastname: Pedro
authors.forename: Edson Zangiacomi
authors.initials: EZ
authors.lastname: Martinez
mesh_terms: D000367:Age Factors; D015992:Body Mass Index; D015519:Bone Density; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007044:Hysterectomy; D016014:Linear Models; D008875:Middle Aged; D017698:Postmenopause / Q000502:physiology; D017697:Premenopause / Q000502:physiology