A simple scheme for the design of solvent-suppression pulses.
Excitation sculpting was first introduced as a way to efficiently suppress solvent signals. It requires a pulse sequence that acts as a null pulse at the solvent-resonance frequency and as an inversion pulse everywhere else. In this article, it is shown that such a goal can be achieved starting with "top-hat" inversion shaped pulses such as I-BURP-2 or gaussian cascade G3. The result is a Globally Antisymmetric Selective Pulse, or GASP. Numerical optimization was used to extend the performance of such pulses. Multifrequency signal suppression was shown to be possible through application of successive excitation sculpting modules.
Prost
Elise
E
Pharmacognosy Laboratory, UMR-A 6013 CNRS, CPCBAI, Bat. 18, BP 1039, Moulin de la Housse, Reims, France. elise.prost@univ-reims.fr
Sizun
Philippe
P
Piotto
Martial
M
Nuzillard
Jean Marc
JM
D002845:Chromatography; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009716:Numerical Analysis, Computer-Assisted; D012997:Solvents
D012997:Solvents