The effects of corticoliberin at different concentrations on long-term potentiation in slices of rat olfactory cortex.
Experiments were performed to investigate evoked focal potentials in slices of rat olfactory cortex. The results showed that 1 microM corticotropin-releasing factor (CRF; corticoliberin) increases the frequency of posttetanic potentiation, which had a shorter delay phase than in control experiments. Posttetanic potentiation during perfusion with 0.1 microM corticoliberin had a longer delay phase than in control experiments.
Lyubimov
Ya E
YE
Laboratory for the Regulation of Brain Neuron Functions, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 6 Makarov Bank, 199034 St. Petersburg, Russia.
Izvaidna
N L
NL
Emel'yanov
N A
NA
Chikhman
V N
VN
Solnushkin
S D
SD
D000818:Animals; D003346:Corticotropin-Releasing Hormone / Q000494:pharmacology*; D004558:Electric Stimulation; D019706:Excitatory Postsynaptic Potentials / Q000187:drug effects; D066298:In Vitro Techniques; D007858:Learning / Q000187:drug effects; D017774:Long-Term Potentiation / Q000187:drug effects*; D008297:Male; D008568:Memory / Q000187:drug effects; D009833:Olfactory Pathways / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D009435:Synaptic Transmission / Q000187:drug effects
D003346:Corticotropin-Releasing Hormone