title: [Effect of hepatic arterial infusion chemotherapy for liver metastasis from gastric cancer].
abstract: We performed hepatic arterial infusion (HAI) chemotherapy for 4 patients with advanced gastric cancer who had undergone curative resection except for liver metastasis. The main antineoplastic drugs were 5-fluorouracil (5-FU), mitomycin C (MMC) and cisplatin (CDDP). A catheter was inserted into the hepatic artery by interventional radiological techniques in 3 patients and operatively in 1 patient. The response rate for 4 patients was 75% (CR2, PR1, PD1). The adverse events were Grade 3/4 nausea and/or vomiting in 2 cases. The HAI chemotherapy was effective and useful for patients with advanced gastric cancer who had no unresectable lesions except for liver metastasis.
authors.affiliation: Dept. of Surgery, Yokosuka Kyousai Hospital.
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Shizawa
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Nagahori
authors.forename: Nobufumi
authors.initials: N
authors.lastname: Kumamoto
authors.forename: Harumi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Kazunaga
authors.initials: K
authors.lastname: Takeda
authors.forename: Youhei
authors.initials: Y
authors.lastname: Hamaguchi
authors.forename: Tadao
authors.initials: T
authors.lastname: Fukushima
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Mogaki
authors.forename: Shingo
authors.initials: S
authors.lastname: Fukasawa
authors.forename: Kazuya
authors.initials: K
authors.lastname: Eguchi
authors.forename: Masaki
authors.initials: M
authors.lastname: Kawahara
authors.forename: Kaoru
authors.initials: K
authors.lastname: Nagahori
authors.forename: Hideo
authors.initials: H
authors.lastname: Hosoi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ohara
mesh_terms: D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000009:adverse effects; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000473:pathology*
chemical_list: D000903:Antibiotics, Antineoplastic; D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D016685:Mitomycin; D002945:Cisplatin; D005472:Fluorouracil