Successful treatment of Candida glabrata myocarditis with voriconazole.
A 30-y-old man with Crohn's disease developed fungemia with Candida albicans. Subsequently, during therapy with fluconazole, Candida glabrata was repeatedly isolated from his blood. Myocardial abscesses were detected in the papillary muscles and interventricular septum. The infection was cured with amphotericin B lipid complex and 5-flucytosine, followed by voriconazole for 18 months.
Einarsdóttir
Hulda M
HM
Department of Medicine, Landspitali University Hospital, Reykjavik, Iceland.
Danielsen
Ragnar
R
Gottfredsson
Magnús
M
D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage*; D041221:Candida glabrata / Q000302:isolation & purification*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D017548:Echocardiography, Transesophageal; D005500:Follow-Up Studies; D016469:Fungemia / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology*; D011743:Pyrimidines / Q000008:administration & dosage*; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage*; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole