title: Transformations of testosterone and related steroids by Botrytis cinerea.
abstract: Botrytis cinerea (strain AM235) was used to investigate the transformations of testosterone and related steroids. It was found that the position and stereochemistry of the introduced hydroxyl group, as well as the yield of products, depended on the structure of the substrate. Botrytis cinerea converts the examined substrates mainly to 7 alpha-hydroxy derivatives. 1-Dehydrotestosterone was also significantly hydroxylated at a 14 alpha-position.
authors.affiliation: Department of Chemistry, Agricultural University, Norwida 25, 50-375 Wroclaw, Poland. huszcza@ozi.ar.wroc.pl
authors.forename: Ewa
authors.initials: E
authors.lastname: Huszcza
authors.forename: Jadwiga
authors.initials: J
authors.lastname: Dmochowska-Gładysz
mesh_terms: D001711:Biotransformation; D020171:Botrytis / Q000201:enzymology / Q000378:metabolism*; D002478:Cells, Cultured; D006900:Hydroxylation; D009682:Magnetic Resonance Spectroscopy; D013256:Steroids / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism*
chemical_list: D013256:Steroids; D013739:Testosterone