title: Hyaluronidase inhibitory activity from the polyphenols in the fruit of blackberry (Rubus fruticosus B.).
abstract: The hyaluronidase inhibitory activity of different fractions obtained from aqueous extract of blackberry fruits was evaluated. We found that only fractions F3 and F7 inhibit the tested enzyme.
authors.affiliation: Grupo de Investigación en Cultivos Celulares, Laboratorio de Bioquímica, Facultad de Farmacia, Universidad de los Andes, Mérida 5101, Venezuela.
authors.forename: M A
authors.initials: MA
authors.lastname: Marquina
authors.forename: G M
authors.initials: GM
authors.lastname: Corao
authors.forename: L
authors.initials: L
authors.lastname: Araujo
authors.forename: D
authors.initials: D
authors.lastname: Buitrago
authors.forename: M
authors.initials: M
authors.lastname: Sosa
mesh_terms: D004791:Enzyme Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D005419:Flavonoids; D005638:Fruit / Q000737:chemistry*; D006821:Hyaluronoglucosaminidase / Q000037:antagonists & inhibitors*; D010636:Phenols / Q000302:isolation & purification* / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D011108:Polymers / Q000302:isolation & purification* / Q000494:pharmacology*; D059808:Polyphenols; D027824:Rosaceae / Q000737:chemistry*
chemical_list: D004791:Enzyme Inhibitors; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D011108:Polymers; D059808:Polyphenols; D006821:Hyaluronoglucosaminidase