title: Mammalian septins nomenclature.
abstract: There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase "v" and a number, e.g., SEPT4_v1.
authors.affiliation: Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA. igm9c@virginia.edu
authors.forename: Ian G
authors.initials: IG
authors.lastname: Macara
authors.forename: Richard
authors.initials: R
authors.lastname: Baldarelli
authors.forename: Christine M
authors.initials: CM
authors.lastname: Field
authors.forename: Michael
authors.initials: M
authors.lastname: Glotzer
authors.forename: Yasuhide
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Shu-Chan
authors.initials: SC
authors.lastname: Hsu
authors.forename: Mary B
authors.initials: MB
authors.lastname: Kennedy
authors.forename: Makoto
authors.initials: M
authors.lastname: Kinoshita
authors.forename: Mark
authors.initials: M
authors.lastname: Longtine
authors.forename: Claudia
authors.initials: C
authors.lastname: Low
authors.forename: Lois J
authors.initials: LJ
authors.lastname: Maltais
authors.forename: Louise
authors.initials: L
authors.lastname: McKenzie
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Mitchison
authors.forename: Toru
authors.initials: T
authors.lastname: Nishikawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Noda
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Petty
authors.forename: Mark
authors.initials: M
authors.lastname: Peifer
authors.forename: John R
authors.initials: JR
authors.lastname: Pringle
authors.forename: Phillip J
authors.initials: PJ
authors.lastname: Robinson
authors.forename: Dagmar
authors.initials: D
authors.lastname: Roth
authors.forename: S E Hilary
authors.initials: SE
authors.lastname: Russell
authors.forename: Heidi
authors.initials: H
authors.lastname: Stuhlmann
authors.forename: Manami
authors.initials: M
authors.lastname: Tanaka
authors.forename: Tomoo
authors.initials: T
authors.lastname: Tanaka
authors.forename: William S
authors.initials: WS
authors.lastname: Trimble
authors.forename: Jerry
authors.initials: J
authors.lastname: Ware
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Zeleznik-Le
authors.forename: Barbara
authors.initials: B
authors.lastname: Zieger
mesh_terms: D017398:Alternative Splicing; D000818:Animals; D003598:Cytoskeletal Proteins; D005656:Fungal Proteins / Q000235:genetics; D020558:GTP Phosphohydrolases / Q000145:classification* / Q000235:genetics; D019204:GTP-Binding Proteins / Q000235:genetics; D006801:Humans; D010802:Phylogeny; D017434:Protein Structure, Tertiary; D058112:Septins; D009626:Terminology as Topic
chemical_list: D003598:Cytoskeletal Proteins; D005656:Fungal Proteins; C410684:PCD1 protein, Pyrenopeziza brassicae; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins; C436485:SEPTIN6 protein, human; C486672:Sept6 protein, mouse; D058112:Septins; C407343:septin 3