Transient mania with hypersexuality after surgery for high frequency stimulation of the subthalamic nucleus in Parkinson's disease.
Among 30 Parkinson's disease patients who received high frequency stimulation of the subthalamic nucleus, 5 developed remarkable disorders of mood or sexual behavior after the implant. We describe 2 men who developed mania and hypersexuality a few days after the implant that lasted for some months and then gradually disappeared spontaneously.
Romito
Luigi Michele
LM
Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy.
Raja
Michele
M
Daniele
Antonio
A
Contarino
Maria Fiorella
MF
Bentivoglio
Anna Rita
AR
Barbier
Annalisa
A
Scerrati
Massimo
M
Albanese
Alberto
A
D000328:Adult; D001143:Arousal / Q000502:physiology; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000503:physiopathology / Q000628:therapy*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000503:physiopathology; D012725:Sexual Behavior / Q000502:physiology*; D020531:Subthalamic Nucleus / Q000503:physiopathology*