Impact of meningococcal vaccination with combined serogroups A and C polysaccharide vaccine on carriage of Neisseria meningitidis C.
Two studies of meningococcal carriage state were carried out in Galicia (Spain) before and after a mass vaccination campaign between December 1996 and January 1997 against Neisseria meningitidis serogroup C with meningococcal serogroups A and C polysaccharide vaccine. The studies covered two areas with different incidence rates of meningococcal disease in 1996 (high and low incidence). Carriage rates of serogroup C showed a decrease in both areas, 47 and 65 % respectively, before and after the vaccination. Results showed a decrease in carrier state in the age groups 10-14- and 15-19-year-olds, but not in the 5-9-year-olds. These results demonstrate the effect of immunization on the reduction of the carriage state.
Fernández
S
S
Dirección Xeral de Saúde Pública, Consellería de Sanidade, 15771 Santiago de Compostela, Galicia, Spain 2Laboratorio de Neisserias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Arreaza
L
L
Dirección Xeral de Saúde Pública, Consellería de Sanidade, 15771 Santiago de Compostela, Galicia, Spain 2Laboratorio de Neisserias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Santiago
I
I
Dirección Xeral de Saúde Pública, Consellería de Sanidade, 15771 Santiago de Compostela, Galicia, Spain 2Laboratorio de Neisserias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Malvar
A
A
Dirección Xeral de Saúde Pública, Consellería de Sanidade, 15771 Santiago de Compostela, Galicia, Spain 2Laboratorio de Neisserias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Berrón
S
S
Dirección Xeral de Saúde Pública, Consellería de Sanidade, 15771 Santiago de Compostela, Galicia, Spain 2Laboratorio de Neisserias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Vazquez
J A
JA
Dirección Xeral de Saúde Pública, Consellería de Sanidade, 15771 Santiago de Compostela, Galicia, Spain 2Laboratorio de Neisserias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Hervada
X
X
Dirección Xeral de Saúde Pública, Consellería de Sanidade, 15771 Santiago de Compostela, Galicia, Spain 2Laboratorio de Neisserias, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008589:Meningococcal Infections / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*; D022401:Meningococcal Vaccines / Q000276:immunology*; D038381:Neisseria meningitidis, Serogroup A / Q000276:immunology* / Q000302:isolation & purification; D038542:Neisseria meningitidis, Serogroup C / Q000276:immunology* / Q000302:isolation & purification; D013030:Spain / Q000453:epidemiology; D014611:Vaccination
D022401:Meningococcal Vaccines