title: An audit of the accuracy of fine needle aspiration using a liquid-based cytology system in the setting of a rapid access breast clinic.
abstract: We have assessed the effectiveness and accuracy of reporting fine needle aspirates of the breast (FNAB) using a liquid-based cytology (LBC) system (the Cytospin) method) in the pressure situation of a rapid access clinic (RAC). We have reviewed every case from the RAC from June 1997 to February 2001 inclusive. There were 1322 cases, which accounted for 26% of the total FNAB received in our department over the period. There were 323 cancers and 999 benign cases in the group. The inadequate/nondiagnostic rate (C1) was 18%. The absolute sensitivity, including C1 cases, was 73% with the complete sensitivity being 90%. The groups of 'atypical, probably benign' (C3) and 'suspicious, probably malignant' (C4) accounted for a total of 6.2%. There were 28 false negative cases and 1 false positive case (a borderline phyllodes tumour). Comparing our results with the standards recommended by the NHSBSP has shown that the diagnosis of FNAB using this LBC method is feasible, accurate and reliable even in the pressure situation of a RAC.
authors.affiliation: Department of Histopathology, Royal Preston Hospital, Preston PR2 4HG, UK.
authors.forename: L
authors.initials: L
authors.lastname: Joseph
authors.forename: J M
authors.initials: JM
authors.lastname: Edwards
authors.forename: C M
authors.initials: CM
authors.lastname: Nicholson
authors.forename: M A
authors.initials: MA
authors.lastname: Pitt
authors.forename: A J
authors.initials: AJ
authors.lastname: Howat
mesh_terms: D000554:Ambulatory Care Facilities / Q000706:statistics & numerical data; D001707:Biopsy, Needle / Q000592:standards* / Q000706:statistics & numerical data; D001943:Breast Neoplasms / Q000473:pathology*; D003951:Diagnostic Errors / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013673:Technology Assessment, Biomedical