title: [Convulsions induced by ropivacaine after midhumeral block].
abstract: We report a case of central nervous system toxicity induced by ropivacaine following a brachial block at the humeral canal. Forty millilitres 0.75% ropivacaine (4.28 mg.kg-1) were used uneventfully, with slow injections and negative intermittent aspirations. Fifteen minutes later, the patient presented two episodes of generalised convulsions treated by diazepam, 20 mg. The total venous ropivacaine concentration measured two hours after the block was 2.3 mg.l-1.
authors.affiliation: Département d'anesthésie, réanimation et urgences, HIA Clermont-Tonnerre, BP 41, 29240 Brest-Naval, France. Mehdi.OA@wanadoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Ould-Ahmed
authors.forename: I
authors.initials: I
authors.lastname: Drouillard
authors.forename: D
authors.initials: D
authors.lastname: Fourel
authors.forename: P
authors.initials: P
authors.lastname: Roussaly
authors.forename: L
authors.initials: L
authors.lastname: Almanza
authors.forename: F
authors.initials: F
authors.lastname: Segalen
mesh_terms: D000577:Amides / Q000009:adverse effects* / Q000097:blood; D000779:Anesthetics, Local / Q000009:adverse effects* / Q000097:blood; D000927:Anticonvulsants / Q000627:therapeutic use; D001917:Brachial Plexus; D003975:Diazepam / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006811:Humerus; D008875:Middle Aged; D009407:Nerve Block / Q000009:adverse effects*; D000077212:Ropivacaine; D012640:Seizures / Q000139:chemically induced* / Q000188:drug therapy
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000927:Anticonvulsants; D000077212:Ropivacaine; D003975:Diazepam