title: [Functional MRI activation in area V4 alpha during a hue arrangement test].
abstract: BACKGROUND
  Recent studies of cerebral information processing have shown that area V4 alpha, the area anterior to area V4, which is known as the human color center, is also associated with color. However, our clinical study has shown that lesions associated with hue arrangement test failures are more anterior than those associated with pseudoisochromatic plate test failure.
  
  
  OBJECTIVE
  We studied area V4 alpha, and planned two functional magnetic resonance experiments for V4 alpha activity during the hue arrangement test. The task in the first experiment was virtual simulation of the hue arrangement test. The second experiment involved a task more specific to color information processing.
  
  
  RESULTS
  We found significant activity in area V4 alpha in healthy subjects.
  
  
  CONCLUSIONS
  We have reported that one of our patients with a more anterior lesion excluding area V4 had dyschromatopsia, as revealed by a panel D-15 test. Our experimental data and the clinical findings suggest that area V4 alpha plays an important role in processing during the hue arrangement test.
authors.affiliation: Department of Ophthalmology, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nakadomari
authors.forename: Kenji
authors.initials: K
authors.lastname: Kitahara
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kandatsu
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Satoru
authors.initials: S
authors.lastname: Miyauchi
mesh_terms: D002540:Cerebral Cortex / Q000502:physiology*; D003118:Color Perception / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male