Cellular mechanisms of cyclophosphamide resistance: model studies in human medulloblastoma cell lines.
Friedman
Henry S
HS
Department of Neuro-Oncology, Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, North Carolina, USA.
Johnson
Stewart P
SP
Colvin
O Michael
OM
D000444:Aldehyde Dehydrogenase / Q000378:metabolism; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D016543:Central Nervous System Neoplasms / Q000188:drug therapy*; D003520:Cyclophosphamide / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use*; D004247:DNA / Q000378:metabolism; D004260:DNA Repair; D019008:Drug Resistance, Neoplasm; D005978:Glutathione / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D006801:Humans; D008527:Medulloblastoma / Q000188:drug therapy*; D008956:Models, Chemical; D014407:Tumor Cells, Cultured
D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide; D004247:DNA; D000444:Aldehyde Dehydrogenase; D005982:Glutathione Transferase; D005978:Glutathione; C011272:perfosfamide