title: Air-containing space in lung adenocarcinoma: high-resolution computed tomography findings.
abstract: OBJECTIVE
  To disclose imaging features of air-containing spaces other than air bronchograms in lung adenocarcinoma on high-resolution computed tomography (HRCT).
  
  
  METHODS
  We retrospectively reviewed HRCT scans of 42 consecutive patients with surgically proved lung adenocarcinoma correlating with pathologic specimens.
  
  
  RESULTS
  Air-containing spaces were seen in 17 (40%) of cases on HRCT. The air-containing spaces appeared as multiple air densities (16 cases [94%]) with variable shapes and had a relatively larger size than that of air bronchograms. Internal septi were often noted (11 cases [65%]).
  
  
  CONCLUSIONS
  Our results demonstrate that multiplicity, larger diameter, and internal septi are the features of air-containing spaces. These findings could be a key to the definitive diagnosis of lung adenocarcinoma, distinguishing it from the mimics such as organizing pneumonia, tuberculoma, or malignant lymphoma.
authors.affiliation: Department of Radiology, Kofu Municipal Hospital, Masutsubo-cho 366, Kofu City, Yamanashi Prefecture, 400-0832 Japan. nambu-a@Comlink.ne.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nambu
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Miyata
authors.forename: Katsura
authors.initials: K
authors.lastname: Ozawa
authors.forename: Masahisa
authors.initials: M
authors.lastname: Miyazawa
authors.forename: Yuuko
authors.initials: Y
authors.lastname: Taguchi
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Araki
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000388:Air; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008223:Lymphoma / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000175:diagnosis; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014375:Tuberculoma / Q000175:diagnosis