title: New and efficient synthesis of azabicyclo[4.4.0]alkane amino acids by Rh-catalyzed cyclohydrocarbonylation.
abstract: [reaction: see text] Highly efficient syntheses of azabicyclo[4.4.0]alkane amino acids were achieved by Rh-catalyzed cyclohydrocarbonylation of dipeptides bearing a terminal olefin moiety and a heteroatom nucleophile.
authors.affiliation: Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794-3400, USA.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Mizutani
authors.forename: Wen-Hua
authors.initials: WH
authors.lastname: Chiou
authors.forename: Iwao
authors.initials: I
authors.lastname: Ojima
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis*; D001372:Aza Compounds / Q000138:chemical synthesis / Q000737:chemistry; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D004151:Dipeptides / Q000138:chemical synthesis / Q000737:chemistry; D018716:Molecular Mimicry; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D017433:Protein Structure, Secondary; D012238:Rhodium / Q000737:chemistry
chemical_list: D000596:Amino Acids; D001372:Aza Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004151:Dipeptides; D010456:Peptides, Cyclic; D012238:Rhodium