title: Enzyme catalysis in ionic liquids.
abstract: Ionic liquids offer new possibilities for the application of solvent engineering to biocatalytic reactions. Although in many cases ionic liquids have simply been used to replace organic solvents, they have often led to improved process performance. Unlike conventional organic solvents, ionic liquids possess no vapor pressure, are able to dissolve many compounds, and can be used to form two-phase systems with many solvents. To date, reactions involving lipases have benefited most from the use of ionic liquids, but the use of ionic liquids with other enzymes and in whole-cell processes has also been described. In some cases, remarkable results with respect to yield, (enantio)selectivity or enzyme stability were observed.
authors.affiliation: Rostock University, Department of Chemistry, Albert-Einstein-Strasse 3a, 18059, Rostock, Germany. udo.kragl@chemie.uni-rostock.de
authors.forename: Udo
authors.initials: U
authors.lastname: Kragl
authors.forename: Marrit
authors.initials: M
authors.lastname: Eckstein
authors.forename: Nicole
authors.initials: N
authors.lastname: Kaftzik
mesh_terms: D001419:Bacteria / Q000145:classification / Q000187:drug effects / Q000201:enzymology*; D002384:Catalysis; D004795:Enzyme Stability; D004798:Enzymes / Q000378:metabolism; D005658:Fungi / Q000145:classification / Q000187:drug effects / Q000201:enzymology*; D005696:Galactosidases / Q000378:metabolism*; D007477:Ions / Q000494:pharmacology; D008049:Lipase / Q000378:metabolism*; D012995:Solubility; D012997:Solvents / Q000494:pharmacology*; D013045:Species Specificity; D013237:Stereoisomerism
chemical_list: D004798:Enzymes; D007477:Ions; D012997:Solvents; D008049:Lipase; D005696:Galactosidases