title: The effect of repeated leishmanin skin testing on the immune responses to Leishmania antigen in healthy volunteers.
abstract: The leishmanin skin test (LST) is used in immunogenicity studies. The effect of multiple LSTs on immune responses was assessed. None of the volunteers converted to LST positive. IFN-gamma and IL-10 levels remained unchanged. Repetition of LST does not modulate the in vivo or in vitro immune responses to Leishmania antigen.
authors.affiliation: Microbiology and Tumour Biology Centre, Karolinska Institute, Box 280, S-171 77 Stockholm, Sweden.
authors.forename: Iman
authors.initials: I
authors.lastname: Satti
authors.forename: Ahmed
authors.initials: A
authors.lastname: el Hassan
authors.forename: El Tahir A G
authors.initials: el TA
authors.lastname: Khalil
authors.forename: Hannah
authors.initials: H
authors.lastname: Akuffo
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D006801:Humans; D007891:Leishmania / Q000276:immunology*; D007896:Leishmaniasis / Q000276:immunology*; D012882:Skin Tests / Q000379:methods; D013397:Sudan
chemical_list: D000953:Antigens, Protozoan; C032127:leishmanin