title: [Bilateral neurotrophic keratitis secondary to encephalic trunk metastasis].
abstract: METHODS
  We report the case of a 69-year-old man with a lung carcinoma history. The patient showed signs of conjuntival hyperemia, painless bilateral corneal edema, persistent epitelial defects and reported to have decreasing visual acuity for a week. The clinical examination revealed a bilateral neurotrophyc keratitis with both a decreased frequency of blinking and a bilateral atrophy mandibular muscles. Local ocular patology was excluded. Systemic exploration showed a meningeal neoplasic infiltration and metastasis on the initial trigeminal nerve stretch. In our knowledge, this is the first case reported in the literature.
  
  
  CONCLUSIONS
  Ophthalmic signs should be considered in the diagnosis of systemic pathology.
authors.affiliation: Servicio de Oftalmología del Hospital Príncipes de España (C.S.U.Bellvitge), Universidad Central de Barcelona, España. danuria@wanadoo.es
authors.forename: N
authors.initials: N
authors.lastname: Ibáñez Flores
authors.forename: S
authors.initials: S
authors.lastname: Sanz Moreno
mesh_terms: D000368:Aged; D003315:Cornea / Q000294:innervation* / Q000473:pathology; D003390:Cranial Nerve Neoplasms / Q000556:secondary*; D006801:Humans; D007634:Keratitis / Q000209:etiology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary*; D009882:Ophthalmic Nerve / Q000473:pathology*