Formation of a remarkably robust 2:1 complex between beta-cyclodextrin and a phenyl-substituted icosahedral carborane.
The structure of the 2:1 complex between beta-cyclodextrin and 1-phenyl-1,2-dicarba-closo-dodecaborane(12) is demonstrated by NOE and NOESY spectroscopy; this complex is remarkably refractory.
Frixa
Christophe
C
Department of Pharmacy & Pharmacology, University of Bath, Claverton Down, Bath, UK BA2 7AY.
Scobie
Martin
M
Black
Steven J
SJ
Thompson
Andrew S
AS
Threadgill
Michael D
MD
D001880:Boranes / Q000737:chemistry*; D016754:Boron Neutron Capture Therapy / Q000379:methods; D003505:Cyclodextrins / Q000737:chemistry*; D004355:Drug Stability; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure
D001880:Boranes; D003505:Cyclodextrins