title: Transient mania with hypersexuality after surgery for high frequency stimulation of the subthalamic nucleus in Parkinson's disease.
abstract: Among 30 Parkinson's disease patients who received high frequency stimulation of the subthalamic nucleus, 5 developed remarkable disorders of mood or sexual behavior after the implant. We describe 2 men who developed mania and hypersexuality a few days after the implant that lasted for some months and then gradually disappeared spontaneously.
authors.affiliation: Istituto di Neurologia, Università Cattolica del Sacro Cuore, Roma, Italy.
authors.forename: Luigi Michele
authors.initials: LM
authors.lastname: Romito
authors.forename: Michele
authors.initials: M
authors.lastname: Raja
authors.forename: Antonio
authors.initials: A
authors.lastname: Daniele
authors.forename: Maria Fiorella
authors.initials: MF
authors.lastname: Contarino
authors.forename: Anna Rita
authors.initials: AR
authors.lastname: Bentivoglio
authors.forename: Annalisa
authors.initials: A
authors.lastname: Barbier
authors.forename: Massimo
authors.initials: M
authors.lastname: Scerrati
authors.forename: Alberto
authors.initials: A
authors.lastname: Albanese
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000503:physiopathology / Q000628:therapy*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000503:physiopathology; D012725:Sexual Behavior / Q000502:physiology*; D020531:Subthalamic Nucleus / Q000503:physiopathology*