title: "Functional-QEMG" a new reliable method in daily routine investigation.
abstract: In classical quantitative analysis motor unit action potentials (MUAPs) parameters are useful in establishing diagnosis, but not in monitoring the functional status as expressed by clinical sings. This drawback is overcome by our new method called "Functional-QEMG", where the analysis is based on structural and functional changes of all acting motor units (MUs). The automatic classification of normal versus myogenic or neurogenic disorder together with the assessment of their severity is performed by special computer-assisted diagnostic procedures. The classification is based on individual MUAPs size (structure) and their functional properties determined in unique "Mapping-MUAP" program. This classification is further confirmed by the adequate to a given pathology the structural reorganisation of all acting MUs. In consequence theirs functional properties are changing as the compensatory mechanisms to generate the optimal force in structurally changed acting MUs. Thus, the effectiveness of compensatory process is used for quantitative assessment of severity of the disease from simultaneously recorded maximal effort pattern. Our experience during last ten years shown that such dynamical analysis is very useful in correlation with the clinical picture of examined patient to make the final conclusion of EMG investigation.
authors.affiliation: Department of Neurology, Medical University of Warsaw, Poland. jkopec@amwaw.edu.pl
authors.forename: J
authors.initials: J
authors.lastname: Kopec
authors.forename: B
authors.initials: B
authors.lastname: Emeryk-Szajewska
mesh_terms: D000200:Action Potentials / Q000502:physiology; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D003955:Diagnostic Tests, Routine / Q000379:methods*; D004576:Electromyography / Q000379:methods*; D006801:Humans; D009046:Motor Neurons / Q000502:physiology; D018482:Muscle, Skeletal / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D015203:Reproducibility of Results