[Prolonged pulmonary artery pressure monitoring in patients with pulmonary hypertension].
Pulmonary artery pressure (PAP) was monitored for 24-48 hours in 10 and 8 patients with primary and secondary pulmonary hypertension, respectively. The data obtained were compared with results of prolonged PAP monitoring in 2 healthy volunteers. Variability of mean PAP was 7.43-/+3.1, 5.78-/+1.64, and 3.4-/+0.63 mm Hg, coefficient of variability - 10.39-/+3.68, 13.04-/+6.01 and 22.73-/+8.03% in patients with primary and secondary pulmonary hypertension and healthy subjects, respectively. After surgery in patients with secondary pulmonary hypertension coefficient of variability rose from 13.04-/+6.01 to 16.7-/+12.8%, while variability decreased from 5.78-/+1.64 to 4.3-/+1.65 mm Hg. Level of spontaneous fluctuations of PAP was the highest in healthy subjects (71.4%) and the lowest - in patients with primary pulmonary hypertension (34.9%). Thus PAP variability is a widespread phenomenon which should be taken into consideration during right heart catheterization and acute pharmacological tests.
Chazova
I E
IE
Kolos
I P
IP
Dzemeshkevich
S L
SL
Samko
A N
AN
Lepilin
M G
MG
Margolina
A A
AA
Staroverov
I I
II
D000293:Adolescent; D000328:Adult; D018660:Blood Pressure Monitoring, Ambulatory; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011651:Pulmonary Artery / Q000503:physiopathology*; D012720:Severity of Illness Index; D013997:Time Factors