title: [Identification of communities endemic for urinary bilharziosis by the "Lot Quality Assurance Sampling" method in Madagascar].
abstract: Reduction of morbidity is the main component in the National Schistosomiasis Control Program in Madagascar. The lot quality assurance sampling (LQAS) method has previously been shown as a useful tool in assessment of immunization coverage. A study was carried in the western part of Madagascar aiming to evaluate the applicability of the method in measuring the level of Schistosoma haematobium endemic level in different communities. Parasitological examination of urine samples from 1,124 children aged 5 to 19 years from 12 different schools by use of filtration technique constituted the reference in determining the prevalence. Three schools were found hyper-endemic (prevalence more than 60%), 5 schools were intermediate-endemic (prevalence between 30 to 59%), and 4 were hypo-endemic (prevalence less than 30%). Those figures indicate a heterogeneous distribution of S. haematobium in the study area. A sampling plan (16.6) was then tested in the same area while other sampling plans were simulated in the laboratory. School teachers randomized under supervision the children to participate in this study and collected urine samples. All sampling plans (16.6), (14.5), (12.4), (10.3), (8.2), (6.1) et (4.0) allowed correct identification of hyper-endemic and hypo-endemic areas. Misclassifications occurred frequently for intermediate-endemic areas. The study confirms that the LQAS method by use of a (16.6) sampling plan constitute a valuable tool for large scale screening of hyper-endemic areas for therapeutic intervention as part of the control program. The study has also shown that school teachers may offer a potential source of manpower locally in such screening operations.
authors.affiliation: Institut Pasteur de Madagascar, BP 1274, 101 Antananarivo, Madagascar.
authors.forename: L P
authors.initials: LP
authors.lastname: Rabarijaona
authors.forename: B J
authors.initials: BJ
authors.lastname: Andriamaroson
authors.forename: V E
authors.initials: VE
authors.lastname: Ravaoalimalala
authors.forename: P
authors.initials: P
authors.lastname: Ravoniarimbinina
authors.forename: R
authors.initials: R
authors.lastname: Migliani
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008270:Madagascar / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods* / Q000592:standards; D011159:Population Surveillance / Q000379:methods*; D015995:Prevalence; D011785:Quality Assurance, Health Care / Q000379:methods*; D012494:Sampling Studies; D012553:Schistosomiasis haematobia / Q000453:epidemiology* / Q000469:parasitology / Q000652:urine; D012572:School Health Services / Q000458:organization & administration*; D012574:Schools; D012680:Sensitivity and Specificity