Recurrent Kawasaki disease-like syndrome in a patient with acquired immunodeficiency syndrome.
A review of Kawasaki disease (KD)-like syndromes (KDLS) in patients with human immunodeficiency virus (HIV) raised the question whether vasculitis in children and KDLS in immunocompromised adults might be etiologically related. We describe a 42-year-old white man with AIDS and Kaposi sarcoma who presented with KDLS, which was diagnosed on the basis of clinical criteria for KD. Analysis of a conjunctival tissue sample revealed endothelial cell damage with fibrin deposition and infiltration of immunoglobulin A-secreting plasma cells.
Blanchard
Jennifer N
JN
Department of Medicine, University of California-San Diego School of Medicine, La Jolla, CA, USA. jblanchard@ucsd.edu
Powell
Henry C
HC
Freeman
William R
WR
Letendre
Scott
S
Blanchard
Daniel
D
Shimizu
Chisato
C
Burns
Jane C
JC
D017088:AIDS-Related Opportunistic Infections / Q000276:immunology / Q000378:metabolism*; D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000328:Adult; D006801:Humans; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000276:immunology / Q000378:metabolism*; D010956:Plasmapheresis; D018124:Receptors, Tumor Necrosis Factor / Q000378:metabolism; D012008:Recurrence
D018124:Receptors, Tumor Necrosis Factor