Arterial thrombosis in a gynecologic oncology patient: evaluation and management.
BACKGROUND
Arterial thrombosis is an extremely rare complication in gynecologic oncology with only two cases previously reported in the literature. Presentation, evaluation, and treatment varied considerably in all previous reports of arterial thrombosis associated with any malignancy.


METHODS
We report a case of discontinuous arterial thrombosis in the upper extremity of a patient with fallopian tube cancer. Her initial evaluation, done in the acute setting of the thrombosis, revealed multiple thrombophilia abnormalities, including an elevated Factor VIII, and a borderline positive lupus anticoagulant. Follow-up studies over 2 years showed resolution of all coagulation abnormalities, thus indicating no genetic propensity for thrombosis.


CONCLUSIONS
This case highlights the need for appropriate timing of the initial laboratory studies and follow-up so that patients can be managed appropriately.
Green
Andrew E
AE
Department of Obstetrics and Gynecology, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio 44106, USA. scout1@core.com
McCrae
Keith
K
Rose
Peter G
PG
D001132:Arm / Q000098:blood supply; D005185:Fallopian Tube Neoplasms / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D013927:Thrombosis / Q000209:etiology* / Q000628:therapy