Interactions between malaria and HIV infection-an emerging public health problem?
Recent evidence demonstrates interactions between malaria and HIV infection. HIV-infected people are more likely to experience clinical malaria, and acute malaria can up-regulate HIV replication, leading to higher plasma viral loads. This is most serious in pregnant women, where HIV infection increases the risk of placental malaria, leading to increased infant morbidity and mortality.
Rowland-Jones
Sarah L
SL
MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, OX3 0DW, Oxford, UK. sarah.rowland-jones@ndm.ox.ac.uk
Lohman
Barbara
B
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000453:epidemiology / Q000469:parasitology*; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D016778:Malaria, Falciparum / Q000453:epidemiology* / Q000276:immunology; D011634:Public Health