title: Parameters of coagulant and fibrinolytic capacity and activity in postmenopausal women: within-subject variability.
abstract: We have analyzed the within-subject variability of a battery of parameters of coagulant and fibrinolytic capacity and activity in postmenopausal women. We observed large differences in within-subject variability among the tests and have demonstrated how such data can be used to estimate the number of times a parameter must be measured to produce a statistically adequate sample.
authors.affiliation: Department of Laboratory Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. mhorne@mail.cc.nih.gov
authors.forename: McDonald K
authors.initials: MK
authors.lastname: Horne
authors.forename: Donna Jo
authors.initials: DJ
authors.lastname: McCloskey
authors.forename: Ann M
authors.initials: AM
authors.lastname: Cullinane
authors.forename: Paula K
authors.initials: PK
authors.lastname: Merryman
authors.forename: Margaret E
authors.initials: ME
authors.lastname: Rick
authors.forename: Glen L
authors.initials: GL
authors.lastname: Hortin
authors.forename: Myron A
authors.initials: MA
authors.lastname: Waclawiw
authors.forename: Richard O
authors.initials: RO
authors.lastname: Cannon
mesh_terms: D015415:Biomarkers / Q000097:blood; D001777:Blood Coagulation; D001779:Blood Coagulation Factors / Q000032:analysis; D005165:Factor V; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D020138:Hyperhomocysteinemia / Q000097:blood; D008137:Longitudinal Studies; D017698:Postmenopause / Q000097:blood*; D015203:Reproducibility of Results
chemical_list: D015415:Biomarkers; D001779:Blood Coagulation Factors; C095381:factor V Leiden; D005165:Factor V