title: Autosomal dominant (AD) pure spastic paraplegia (HSP) linked to locus SPG4 affects almost exclusively males in a large pedigree.
authors.forename: A
authors.initials: A
authors.lastname: Starling
authors.forename: P
authors.initials: P
authors.lastname: Rocco
authors.forename: M R
authors.initials: MR
authors.lastname: Passos-Bueno
authors.forename: J
authors.initials: J
authors.lastname: Hazan
authors.forename: S K
authors.initials: SK
authors.lastname: Marie
authors.forename: M
authors.initials: M
authors.lastname: Zatz
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics*; D002874:Chromosome Mapping; D004252:DNA Mutational Analysis; D005260:Female; D005799:Genes, Dominant / Q000235:genetics*; D008040:Genetic Linkage / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D008126:Lod Score; D008297:Male; D010375:Pedigree; D012727:Sex Characteristics; D015419:Spastic Paraplegia, Hereditary / Q000235:genetics*; D000074181:Spastin
chemical_list: D000251:Adenosine Triphosphatases; D000074181:Spastin; C400283:SPAST protein, human