Antioxidant properties of carboxymethyl glucan: comparative analysis.
Antioxidative capabilities of carboxymethylated (1 --> 3)-beta-D-glucan from Saccharomyces cerevisiae cell wall, alpha-tocopherol, and mannitol against lipid peroxidation in phosphatidylcholine liposomes induced by OH. radicals produced with Fenton's reagent (H(2)O(2)/Fe(2+)) were studied using absorption ultraviolet-visible spectrophotometry. It was found that (1 --> 3)-beta-D-glucan is an antioxidant with the scavenging ability lying between that of alpha-tocopherol, which is known to be incorporated in the lipid bilayer, and the water-soluble antioxidant, mannitol.
Babincová
M
M
Department of Biophysics and Chemical Physics, Comenius University, Bratislava, Slovakia. babincova@fmph.uniba.sk
Bacová
Z
Z
Machová
E
E
Kogan
G
G
D000975:Antioxidants / Q000494:pharmacology*; D002473:Cell Wall / Q000737:chemistry; D016166:Free Radical Scavengers / Q000494:pharmacology*; D005936:Glucans / Q000494:pharmacology*; D006801:Humans; D006861:Hydrogen Peroxide; D017665:Hydroxyl Radical / Q000378:metabolism; D066298:In Vitro Techniques; D007501:Iron; D008051:Lipid Bilayers / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects*; D008081:Liposomes; D008353:Mannitol / Q000494:pharmacology*; D016877:Oxidants / Q000378:metabolism; D010713:Phosphatidylcholines / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000737:chemistry; D012995:Solubility; D013056:Spectrophotometry, Ultraviolet; D024502:alpha-Tocopherol / Q000494:pharmacology*; D047071:beta-Glucans
D000975:Antioxidants; C045076:Fenton's reagent; D016166:Free Radical Scavengers; D005936:Glucans; D008051:Lipid Bilayers; D008081:Liposomes; D016877:Oxidants; D010713:Phosphatidylcholines; D047071:beta-Glucans; D017665:Hydroxyl Radical; D008353:Mannitol; C029933:carboxymethyl-beta-1,3-glucan; D006861:Hydrogen Peroxide; D007501:Iron; D024502:alpha-Tocopherol