Proprioception-related evoked potentials: origin and sensitivity to movement parameters.
Reafferent electroencephalography (EEG) potentials evoked by active or passive movement are largely dependent on muscle spindle input, which projects to postrolandic sensory areas as well as the precentral motor cortex. The origin of these proprioception-related evoked potentials has previously been studied by using N20-P20 source locations of the median nerve somatosensory evoked potential as an landmark for postcentral area 3b. As this approach has yielded contradictory findings, likely due to spatial undersampling, we applied dipole source analysis on two independently collected sets of high-density EEG data, containing the proprioception-related N90 elicited by passive finger movement, and the N20-P20 elicited by median nerve stimulation. In addition, the influence of movement parameters on the N90 was explored by varying amplitude/duration and direction of passive movements. The results showed that the proprioceptive N90 component was not influenced by movement direction, but had a duration that covaried with the duration of the movement. Sources were localized in the precentral cortex, located on average 10 mm anterior to the N20-P20 sources. The latter result supports earlier claims that the motor cortex is involved in the generation of proprioception-related EEG potentials.
Seiss
E
E
Behavioural Brain Sciences Centre, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Hesse
C W
CW
Drane
S
S
Oostenveld
R
R
Wing
A M
AM
Praamstra
P
P
D000328:Adult; D003627:Data Interpretation, Statistical; D004558:Electric Stimulation; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D005260:Female; D005385:Fingers / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000502:physiology; D009068:Movement / Q000502:physiology*; D011434:Proprioception / Q000502:physiology*