[Features of daily rhythm of arterial pressure in patients with primary arterial hypertension and neurogenic syncope conditions].
OBJECTIVE
A comparative analysis of parameters of systemic BP in patients with primary arterial hypotension (PAH) and in patients with neurogenic syncopes (NS) in the cycle sleep-awake.


METHODS
Blood pressure was investigated in 20 patients with PAH aged 16-44 years and 18 patients with NS aged 16-49 years. 24-h ambulatory monitoring of BP was made on the monitor ABPM-02/M (Meditech, Hungary).


RESULTS
Rhythm indices of BP in NS patients corresponded to age normal criteria. 24-h arrhythmia of BP in PAH patients manifests with excessive drop of diastolic BP in sleep (55% patients were overdippers). PAH and NS patients differ maximally by hypotonic load in sleep: 1.0 +/- 0.7% in NS vs 15.4 +/- 3.2% in PAH. Hypotonia episodes in awake PAH patients were registered at each 4th-5th measurement of BP, in NS patients--at each 11th-13th. Heart rate in awake PAH patients is higher than in healthy subjects.


CONCLUSIONS
Hypotonic load in sleep carries the highest differentially-diagnostic importance. This makes more perspective examinations of such patients in the cycle sleep-awake. The changes observed in PAH patients evidence for activation of cerebral sympathico-adrenal systems participating in baroreflex regulation.
Musaeva
Z A
ZA
Oknin
V Iu
VIu
Khapaev
B A
BA
Fedotova
A V
AV
Veĭn
A M
AM
D000293:Adolescent; D000328:Adult; D002940:Circadian Rhythm; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008875:Middle Aged; D012890:Sleep; D019462:Syncope, Vasovagal / Q000150:complications / Q000503:physiopathology*; D014851:Wakefulness