GITR interacts with the pro-apoptotic protein Siva and induces apoptosis.
Spinicelli
S
S
Nocentini
G
G
Ronchetti
S
S
Krausz
L T
LT
Bianchini
R
R
Riccardi
C
C
D000595:Amino Acid Sequence / Q000235:genetics; D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D051017:Apoptosis Regulatory Proteins; D019556:COS Cells; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism; D005057:Eukaryotic Cells / Q000378:metabolism*; D053450:Glucocorticoid-Induced TNFR-Related Protein; D047908:Intracellular Signaling Peptides and Proteins; D051379:Mice; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D011485:Protein Binding / Q000502:physiology; D017434:Protein Structure, Tertiary / Q000502:physiology; D017475:Receptors, Nerve Growth Factor / Q000235:genetics / Q000378:metabolism*; D053262:Receptors, OX40; D018124:Receptors, Tumor Necrosis Factor / Q000235:genetics / Q000378:metabolism*; D018127:Tumor Necrosis Factor Receptor Superfamily, Member 7 / Q000235:genetics / Q000378:metabolism
D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins; D053450:Glucocorticoid-Induced TNFR-Related Protein; D047908:Intracellular Signaling Peptides and Proteins; D017475:Receptors, Nerve Growth Factor; D053262:Receptors, OX40; D018124:Receptors, Tumor Necrosis Factor; C484569:Siva protein, mouse; C491405:TNFRSF18 protein, human; C505716:TNFRSF4 protein, human; C106544:Tnfrsf18 protein, mouse; C505717:Tnfrsf4 protein, mouse; D018127:Tumor Necrosis Factor Receptor Superfamily, Member 7