title: Using transcriptional-based systems for in vivo enzyme screening.
authors.affiliation: Department of Medicinal Chemistry, Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA, USA.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Firestine
authors.forename: Frank
authors.initials: F
authors.lastname: Salinas
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Benkovic
mesh_terms: D003001:Cloning, Molecular; D020650:Combinatorial Chemistry Techniques; D004353:Drug Evaluation, Preclinical; D004798:Enzymes / Q000235:genetics* / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005822:Genetic Vectors; D017434:Protein Structure, Tertiary; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D013379:Substrate Specificity; D014158:Transcription, Genetic; D020798:Two-Hybrid System Techniques
chemical_list: D004798:Enzymes; D011994:Recombinant Proteins