title: [A case of metastatic gastric cancer treated with CDDP plus TS-1 and surgical resection].
abstract: Advanced gastric cancer (AGC) with liver metastasis has a poor prognosis. We encountered a case of AGC with multiple liver metastasis treated with chemotherapy and surgery.
  
  
  METHODS
  A 54-year-old male. He was admitted to our hospital with epigastric pain. Gastrointestinal fiberscope examination revealed gastric cancer. A CT scan showed regional and para-aortic lymph node (LN) swelling and multiple hepatic metastasis in the left hepatic lobe. The serum CEA level was 100.6 ng/dl. He was administered 4 courses of CDDP (100 mg (day 8 i.v.)) plus TS-1 (120 mg/day day 1-21 p.o.). After the chemotherapy, CT showed a reduction of liver metastasis and disappearance of the LN swelling. The serum CEA levels were normalized. Distal gastrectomy, partial hepatectomy, and microwave coagulation therapy were performed. After operation, he was administered 4 courses of CDDP/TS-1 additionally. Surgery may be one of therapeutic option for AGC with liver metastasis that has responded to chemotherapy, as in the present case.
authors.affiliation: Dept. of Surgery, Sakai Municipal Hospital.
authors.forename: Junzo
authors.initials: J
authors.lastname: Shimizu
authors.forename: Seizo
authors.initials: S
authors.lastname: Masutani
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imamura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Furukawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kato
authors.forename: Kouji
authors.initials: K
authors.lastname: Ezumi
authors.forename: Norikazu
authors.initials: N
authors.lastname: Masuda
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Ishida
authors.forename: Masayuki
authors.initials: M
authors.lastname: Tatsuta
authors.forename: Takatoshi
authors.initials: T
authors.lastname: Kawasaki
mesh_terms: D000230:Adenocarcinoma / Q000628:therapy*; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D014408:Biomarkers, Tumor / Q000097:blood; D002272:Carcinoembryonic Antigen / Q000097:blood; D002945:Cisplatin / Q000008:administration & dosage; D005743:Gastrectomy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology* / Q000628:therapy*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000964:Antimetabolites, Antineoplastic; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D005641:Tegafur; D002945:Cisplatin