Quantitative sensory testing: high sensitivity in small fiber neuropathy with normal NCS/EMG.
We evaluated the diagnostic sensitivity of quantitative sensory testing (QST), using the CASE IV system, in 14 patients with clinically diagnosed small-fiber neuropathy and normal traditional electrodiagnostic studies. All patients had at least 1 abnormal threshold, 13 patients had abnormal heat-pain thresholds, 8 had abnormal cold thresholds, and 7 had abnormal vibration thresholds. QST is therefore highly effective in documenting dysfunction in small fiber neuropathy patients.
Magda
Paul
P
Peripheral Neuropathy Center, Department of Neurology and Neuroscience, Weill Medical College of Comell University, New York, NY 10022, USA.
Latov
Norman
N
Renard
Michelle V
MV
Sander
Howard W
HW
D000328:Adult; D004576:Electromyography / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000502:physiology*; D009422:Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology*; D017288:Pain Threshold / Q000502:physiology; D012189:Retrospective Studies