[Fatal and nonfatal cardiovascular complications in patients with essential hypertension (hypertensive disease) during follow-up for many years].
Fatal and nonfatal complications (stroke, myocardial infarction, chronic heart failure, sudden coronary death, chronic renal insufficiency) were registered during long term follow-up of 529 patients with hypertensive disease and results were analyzed retrospectively. Duration of ambulatory treatment in two thirds of patients exceeded 15 years. There were 243 deaths in 1993-1999. Mean age of those who died was 75 years. Main fatal complications were strokes and myocardial infarctions. Their rates were similar. Strokes comprised one third of all deaths irrespective of age. There were no significant differences between rates of ischemic and hemorrhagic strokes. Among causes of death proportion of sudden death was the highest in patients younger than 60 years while that of chronic heart failure rose with age. There were no cases of chronic renal failure. Atherosclerotic lesions in coronary and cerebral vessels were found at autopsies irrespective of cause of death.
Alekseeva
L A
LA
Vakhlakov
A N
AN
Sergeeva
E V
EV
Perov
Yu L
YL
Gasilin
B C
BC
Chorbinskaia
S A
SA
Gribunov
Yu P
YP
D000368:Aged; D000959:Antihypertensive Agents / Q000145:classification / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology* / Q000401:mortality; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies
D000959:Antihypertensive Agents