Interactions of cyclodextrins with aromatic compounds studied by vibrational circular dichroism spectroscopy.
The host/guest complexation between cyclodextrins (CDs) and aromatic compounds was studied by vibrational circular dichroism (VCD) spectroscopy in mid-IR region. Benzoic acid, 4-aminobenzoic acid, and 2,6-naphthalene-dicarboxylic acid acting as the guests with aromatic skeleton, cause the significant changes in VCD patterns of CD, which indicate that the secondary hydroxyl groups of the CDs are involved in the host/guest complexation. In addition, the intensities and dissymmetry factors (deltaA/A) of the VCD bands, which belong to skeletal CD vibrations, depend on the sizes of the guest molecules. Our results indicate that the formation of the CD inclusion complexes can be followed by VCD spectroscopy.
Setnicka
Vladimir
V
Department of Analytical Chemistry, Institute of Chemical Technology, Technická 5, 166 28 Praha 6, Czech Republic. vladimir.setnicka@vscht.cz
Urbanová
Marie
M
Král
Vladimír
V
Volka
Karel
K
D001565:Benzoates / Q000737:chemistry*; D002942:Circular Dichroism; D003505:Cyclodextrins / Q000737:chemistry*; D003998:Dicarboxylic Acids / Q000737:chemistry*; D009281:Naphthalenes / Q000737:chemistry*
D001565:Benzoates; D003505:Cyclodextrins; D003998:Dicarboxylic Acids; D009281:Naphthalenes; C109064:2,6-naphthalenedicarboxylic acid