title: Systemic capillary leak syndrome.
abstract: Systemic capillary leak syndrome (SCLS) is characterized by recurrent hypovolemic shock attributable to increased systemic capillary leakage. A 46-year-old man was admitted to our hospital because of recurrent episodes of generalized edema with hypovolemic shock. Blood laboratory data revealed severe hypoproteinemia with a small monoclonal IgG-kappa protein. These findings suggested strongly the diagnosis of SCLS. A regimen with steroid pulse therapy was tried; however, intravascular overloading accompanied by the recruitment of the initially extravasated fluids resulted in acute pulmonary edema. Intensive care and careful monitoring of fluid volume are required in SCLS.
authors.affiliation: Department of Nephrology, Saitama Medical School, Iruma-gun, Saitama.
authors.forename: Ruri
authors.initials: R
authors.lastname: Chihara
authors.forename: Hidetomo
authors.initials: H
authors.lastname: Nakamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Arima
authors.forename: Kenshi
authors.initials: K
authors.lastname: Moriwaki
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Kanno
authors.forename: Soichi
authors.initials: S
authors.lastname: Sugahara
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Okada
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D019559:Capillary Leak Syndrome / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged