title: Prognosis of parathyroid function after minimally invasive radioguided parathyroidectomy (MIRP) and percutaneous ethanol injection therapy (PEIT) for primary hyperparathyroidism.
abstract: During parathyroidectomy (PTx) for primary hyperparathyroidism (PHP), we surgically explored the contralateral parathyroid glands as well as those whose localization was clarified by ultrasonography and parathyroid scintigraphy. Although it is important to explore the contralateral side and other glands, we frequently treat only the gland whose localization is confirmed. Recently, we have performed minimally invasive radioguided parathyroidectomy (MIRP) that resects only one gland observed on the imaging under technetium 99m-labeled sestamibi (MIBI) scanning guidance after obtaining prior informed consent. In this surgery, even if recurrence is observed contralaterally, it is possible to apply a similar procedure to the contralateral side again. We examined six PHP patients who underwent MIRP and two PHP patients treated with percutaneous ethanol injection therapy (PEIT). The follow-up period was 2 years. PEIT was selected as a treatment method for two patients based on the patients' characteristics. When only one gland is treated, the efficacy of PEIT was considered to be similar to that of MIRP.
authors.affiliation: Department of Internal Medicine, Tokai University School of Medicine, Bohseidai Isehara, Kanagawa, 259-1193, Japan. kakuta@wc4.so-net.ne.jp
authors.forename: Takatoshi
authors.initials: T
authors.lastname: Kakuta
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Futoshi
authors.initials: F
authors.lastname: Tadaki
authors.forename: Katsuya
authors.initials: K
authors.lastname: Uemura
authors.forename: Reika
authors.initials: R
authors.lastname: Tanaka
authors.forename: Shinichi
authors.initials: S
authors.lastname: Tanaka
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Kubota
authors.forename: Hideto
authors.initials: H
authors.lastname: Sakai
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Kurokawa
authors.forename: Akira
authors.initials: A
authors.lastname: Saito
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016105:Parathyroidectomy / Q000295:instrumentation / Q000379:methods*; D011379:Prognosis; D011877:Radionuclide Imaging; D018709:Statistics, Nonparametric; D017256:Technetium Tc 99m Sestamibi
chemical_list: D000431:Ethanol; D017256:Technetium Tc 99m Sestamibi