Proton MR spectroscopy of cerebellitis.
Single voxel proton MR spectroscopy ((1)H-MRS) of the vermis was obtained in two patients with cerebellitis. In the acute phase (1)H-MRS revealed low N-acetyl-aspartate (NAA)/creatine (Cr) and NAA/choline (Cho) and normal Cho/Cr ratios. Decrease of the concentration of NAA was confirmed by quantitative analysis in one patient. The NAA/Cr and NAA/Cho ratios and NAA concentration were increased in (1)H-MRS examinations obtained 10 and 24 months after the acute episode. (1)H-MRS demonstrates reversible metabolite changes in cerebellitis.
Guerrini
Laura
L
Radiodiagnostica I, Dipartimento di Fisiopatologia Clinica, Università di Firenze, Viale Morgagni 85, Italy.
Belli
Giacomo
G
Cellerini
Martino
M
Nencini
Patrizia
P
Mascalchi
Mario
M
D000210:Acute-Phase Reaction / Q000378:metabolism; D000328:Adult; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000378:metabolism* / Q000473:pathology; D002794:Choline / Q000378:metabolism; D003401:Creatine / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011522:Protons
D011522:Protons; D001224:Aspartic Acid; C000179:N-acetylaspartate; D003401:Creatine; D002794:Choline