Proceedings of the 10th International Conference on Neuroscience of HIV Infection: emerging issues.
The 10th International Conference on Neuroscience of HIV Infection was held conjointly with the 4th International Symposium on NeuroVirology. This review summarizes a number of important topics addressed at the conference including clinical aspects of HIV-1 associated dementia and peripheral nervous system pathology and their epidemiology in the era of highly active antiretroviral therapy. The neuropathogenesis was discussed with a special focus on different cellular compartments involved, viral and non-viral factors, immune activation, and alterations of the blood-brain barrier, animal models and their relevance for understanding HIV dementia. New aspects of antiretroviral therapy as well as immunization were covered. Neuroradiological approaches including new MR techniques and neuropsychological tests were presented. Viral opportunistic infections (e.g., JCV infection resulting in progressive multifocal leukoencephalopathy) as well as coinfection with hepatitis C represented a further topic.
von Giesen
Hans-Jürgen
HJ
Neurologische Klinik der Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany. giesenhj@uni-duesseldorf.de
Arendt
Gabriele
G
Berger
Joseph R
JR
Levy
Robert
R
D015526:AIDS Dementia Complex; D006801:Humans; D009488:Neurosciences / Q000639:trends*; D014773:Virology / Q000639:trends*