Rituximab: a useful drug for a repeatedly relapsed hairy cell leukemia patient.
We describe a case of complete response in a patient with hairy cell leukemia, relapsed after treatment with interferon-alpha, 2'-deoxycoformicin, and 2-chlorodeoxyadenosine, and then successfully treated with rituximab. A fourfold reduction of leukemic cells was observed concomitantly with restoration of normal blood count and differential.
Pollio
F
F
Divisione di Ematologia, AORN A. Cardarelli, Via Cardarelli 9, 80131 Naples, Italy. filibpol@tin.it
Pocali
B
B
Palmieri
S
S
Morabito
P
P
Scalia
G
G
Del Vecchio
L
L
Ferrara
F
F
D000328:Adult; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D058846:Antibodies, Monoclonal, Murine-Derived; D017338:Cladribine / Q000008:administration & dosage; D006801:Humans; D016898:Interferon-alpha / Q000008:administration & dosage; D007943:Leukemia, Hairy Cell / Q000188:drug therapy*; D008297:Male; D015649:Pentostatin / Q000008:administration & dosage; D012008:Recurrence; D012074:Remission Induction; D000069283:Rituximab; D016879:Salvage Therapy
D000911:Antibodies, Monoclonal; D058846:Antibodies, Monoclonal, Murine-Derived; D016898:Interferon-alpha; D015649:Pentostatin; D017338:Cladribine; D000069283:Rituximab