title: Abeta conformational change is central to Alzheimer's disease.
authors.affiliation: Department of Neurology, Center for the Study of Nervous System Injury, Alzheimer's Disease Research Center, Washington University School of Medicine, 660 S. Euclid Avenue, Box 8111, St. Louis, MO 63110, USA. holtzmann@neuro.wustl.edu
authors.forename: David M
authors.initials: DM
authors.lastname: Holtzman
mesh_terms: D000544:Alzheimer Disease / Q000235:genetics / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000737:chemistry / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000686:Amyloidosis / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism / Q000473:pathology; D005427:Flocculation; D006801:Humans; D008670:Metals / Q000378:metabolism; D051379:Mice; D008822:Mice, Transgenic; D008968:Molecular Conformation; D058225:Plaque, Amyloid / Q000378:metabolism*
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D008670:Metals