title: Adult case of squamous cell carcinoma arising on congenital esophageal stenosis due to fibromuscular hypertrophy.
abstract: This study relates to an adult case of squamous cell carcinoma arising on congenital esophageal stenosis. The patient was a 65-year-old man who had suffered from dysphagia and vomiting since birth and was diagnosed as having congenital esophageal stenosis. The patient had not received any treatment because his symptoms were mild. The patients suffered from severe dysphagia since he was 20 years old and had received balloon therapies several times; however, the effects were transient. After admission to our hospital, he underwent a transhiatal esophagectomy without thoracotomy. Histopathological examination of the resected specimen revealed a thick muscular mucosae associated with hypertrophic fibromuscular components and poorly to moderately differentiated squamous cell carcinoma in the region of stenosis. This case report is the first of a patient with squamous cell carcinoma arising on congenital esophageal stenosis.
authors.affiliation: Department of Surgery I, Kumamoto University School of Medicine, 1-1-1, Honjo, Kumamoto, Japan. makihisa@kaiju.medic.kumamoto-u.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Tabira
authors.forename: M
authors.initials: M
authors.lastname: Yasunaga
authors.forename: T
authors.initials: T
authors.lastname: Sakaguchi
authors.forename: T
authors.initials: T
authors.lastname: Okuma
authors.forename: Y
authors.initials: Y
authors.lastname: Yamaguchi
authors.forename: H
authors.initials: H
authors.lastname: Kuhara
authors.forename: Y
authors.initials: Y
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Iyama
authors.forename: M
authors.initials: M
authors.lastname: Kawasuji
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D004938:Esophageal Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D004940:Esophageal Stenosis / Q000150:complications / Q000151:congenital / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology*; D006801:Humans; D006984:Hypertrophy; D008297:Male