title: Co-transcriptional monitoring of mRNP formation.
abstract: In eukaryotes, newly manufactured mRNA is subject to strict quality control. If certain standards are not met, offending messages are retained in the nucleus and degraded by the exosome complex. New data suggest that exosome-mediated processes are intimately coupled to the transcription machinery, which makes the mRNA in the first place.
authors.forename: Torben Heick
authors.initials: TH
authors.lastname: Jensen
authors.forename: Michael
authors.initials: M
authors.lastname: Rosbash
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000235:genetics / Q000378:metabolism; D008954:Models, Biological; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000235:genetics*
chemical_list: D012333:RNA, Messenger