title: Improving antisense oligonucleotide binding to human serum albumin: dramatic effect of ibuprofen conjugation.
authors.affiliation: Isis Pharmaceuticals, Inc, Carlsbad, CA 92008, USA. mmanoharan@isisph.com
authors.forename: Muthiah
authors.initials: M
authors.lastname: Manoharan
authors.forename: Gopal B
authors.initials: GB
authors.lastname: Inamati
authors.forename: Elena A
authors.initials: EA
authors.lastname: Lesnik
authors.forename: Namir B
authors.initials: NB
authors.lastname: Sioufi
authors.forename: Susan M
authors.initials: SM
authors.lastname: Freier
mesh_terms: D006801:Humans; D007052:Ibuprofen / Q000737:chemistry* / Q000494:pharmacology; D016376:Oligonucleotides, Antisense / Q000737:chemistry*; D011485:Protein Binding / Q000187:drug effects; D012709:Serum Albumin / Q000378:metabolism*
chemical_list: D016376:Oligonucleotides, Antisense; D012709:Serum Albumin; D007052:Ibuprofen