The effect of Mangifera indica stem bark and Pluchea ovalis roots on tracheal smooth muscle in vitro.
Aqueous extract of the stem bark of Mangifera indica and ethanolic extract of the roots of Pluchea ovalis has been studied on rat tracheal smooth muscle in vitro. The extract of M. indica at 1, 2 and 4 mg/ml and that of P. ovalis at 0.25, 0.5 and 1 mg/ml relaxed, dose-dependently, the rat tracheal smooth muscle strip previously contracted by acetylcholine at 0.055 mmol/l.
Agbonon
Amégnona
A
Département de Physiologie/Pharmacologie Faculté des Sciences, Université de Lomé BP, 1515 Lomé, Togo.
Eklu-Gadegbeku
Kwashie
K
Aklikokou
Kodjo
K
Essien
Komlan
K
Akpagana
Koffi
K
Gbeassor
Messanvi
M
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D016015:Logistic Models; D031022:Mangifera / Q000737:chemistry*; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D051381:Rats; D014132:Trachea / Q000187:drug effects*
D010936:Plant Extracts; D000109:Acetylcholine