Antibody discovery: phage display.
Phage display has proven to be a robust and convenient technology for the selection of high-quality human antibodies from diverse libraries. Besides enabling the identification of antibodies in a fast, high-throughput mode, which allows comprehensive protein expression analyses, phage display has been used to identify a fully human therapeutic antibody presently undergoing the regulatory process for market approval.
Kretzschmar
Titus
T
MorphoSys AG, Lena-Christ-Strasse 48, D-82152, Martinsried, Germany. tik@morphosys.com
von Rüden
Thomas
T
D000906:Antibodies / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification*; D000918:Antibody Specificity / Q000235:genetics*; D001435:Bacteriophages / Q000235:genetics*; D005803:Genes, Immunoglobulin; D019151:Peptide Library
D000906:Antibodies; D019151:Peptide Library