title: [Necrotic eosinophilic angiitis with ileal perforation and peritonitis secondary to abdominal angiostrongyliasis].
abstract: BACKGROUND
  Abdominal angiostrongyliasis caused by the filiform nematode Angiostrongylus costaricensis, is an endemic disease in Central and South America. A case of necrotic eosinophilic angeitis with ileum perforation and peritonitis due to abdominal angiostrongyliasis is reported.
  
  
  METHODS
  A 32 year-old man, living in a Paris suburb, underwent segmentary resection of the ileum with end to end anastomosis for perforation with generalized peritonitis. The anatomopathological examination revealed eosinophilic necrotic lesions with thrombosis on the borders of the ileum perforation. The discovery of a section of A. costaricensis in the lumen of a nearby muscular artery initiated an epidemiological survey, revealing that the patient had visited French Guyana 2 months earlier.
  
  
  CONCLUSIONS
  Angiostrongylus costaricensis is a nematode parisiting certain forest rodents that become its permanent host. The intermediate hosts are earth molluscs or slugs of the same family. Humans are accidentally infected following ingestion of vegetables infested with L3 larvae or slugs carrying the disease. The clinical symptomatology is unspecific: prolonged fever, anorexia, and right iliac fossa pain with eosinophilia of the blood. Often benign, the progression of abdominal angiostrongylosis is punctuated by complications: occlusive syndrome, generalised peritonitis due to intestinal perforation and mass syndrome. Hemorrhage, infarct, pseudo-tumoural fibrosis and ulcers represent the surgical or macroscopic rearrangements. In the tissue, 4 lesions characterize abdominal angiostrongylosis: eosinophilic necrotic angeitis, foreign body granulomas, eosinophilia in the digestive wall, and the presence of A. costaricensis in the lumen of the vessels. There is presently no medical treatment and surgery is the only therapeutic option.
authors.affiliation: Unité d'anatomie et de cytologie pathologiques, Hôpital Saint-Michel 33, rue Olivier de Serres, 75730 Paris. vuongocphat@wanadoo.fr
authors.forename: P N
authors.initials: PN
authors.lastname: Vuong
authors.forename: Ph
authors.initials: P
authors.lastname: Brama
authors.forename: R
authors.initials: R
authors.lastname: Bonète
authors.forename: S
authors.initials: S
authors.lastname: Houissa-Vuong
authors.forename: M
authors.initials: M
authors.lastname: Catanzano-Laroudie
authors.forename: E
authors.initials: E
authors.lastname: Baviera
mesh_terms: D000005:Abdomen; D000328:Adult; D004802:Eosinophilia / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D007077:Ileal Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D007416:Intestinal Perforation / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D009336:Necrosis; D010538:Peritonitis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013322:Strongyloidiasis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology