Zebrafish as an immunological model system.
Two decades of research have established the zebrafish (Danio rerio) as a significant model system for studying vertebrate development and gene structure-function relationships. Recent advances in mutation screening, the creation of genomic resources, including the Zebrafish Genome Project and the development of efficient transgenesis procedures, make this model increasingly attractive for immunological study.
Yoder
Jeffrey A
JA
Department of Biology, University of South Florida, 4202 East Fowler Avenue, Tampa, FL 33620, USA.
Nielsen
Michael E
ME
Amemiya
Chris T
CT
Litman
Gary W
GW
D000818:Animals; D005393:Fish Diseases / Q000276:immunology; D007110:Immunity, Active / Q000235:genetics; D007113:Immunity, Innate / Q000502:physiology; D007694:Killer Cells, Natural / Q000276:immunology; D023421:Models, Animal; D018448:Models, Immunological; D016296:Mutagenesis; D019076:Transgenes; D015027:Zebrafish / Q000235:genetics / Q000276:immunology*