title: [Pulmonary resection for metastatic colorectal cancer].
abstract: We reviewed the clinical courses of 25 patients who underwent pulmonary resection for metastatic lesions from colorectal cancer between January 1991 and December 2001. The cumulative survivals at 3 and 5 years were 72% and 63%, respectively. Sex, site of the primary tumor, presence of extrapulmonary metastases, disease-free interval, location of pulmonary metastases (PM), number of PM, size of PM, mode of operation, pre-thoracotomy serum carcinoembryonic antigen level, and post-thoracotomy chemotherapy were not found to be statistically significant prognostic factors. Age (70 years < or =) was a predictor of a shorter survival duration by univariate analysis (p = 0.02). Recurrence was observed in 19 patients, 11 of which were lung recurrences. Eight patients underwent repeated pulmonary resection. The median survival in these 8 patients was 23 months after second pulmonary operation. Surgical treatment for pulmonary metastases from colorectal cancer in selected patients might improve prognosis.
authors.affiliation: Dept. of Surgery, National Shikoku Cancer Center Hospital.
authors.forename: Minoru
authors.initials: M
authors.lastname: Tanada
authors.forename: Masao
authors.initials: M
authors.lastname: Nakata
authors.forename: Yoshirou
authors.initials: Y
authors.lastname: Kubo
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Saeki
authors.forename: Kenjirou
authors.initials: K
authors.lastname: Aogi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ishizaki
authors.forename: Akira
authors.initials: A
authors.lastname: Kurita
authors.forename: Shigemitsu
authors.initials: S
authors.lastname: Takashima
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000097:blood; D015179:Colorectal Neoplasms / Q000473:pathology*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D011379:Prognosis; D012086:Reoperation; D012738:Sex Hormone-Binding Globulin
chemical_list: D002272:Carcinoembryonic Antigen; D012738:Sex Hormone-Binding Globulin