Study of the 111In-DTPA complex by the electromigration method.
The electrophoretic behavior of the 111In-DTPA radiopharmaceutical has been investigated. The stability constant, diffusion coefficient and effective charge of the complex as well as the temperature dependence of the electrophoretic mobility were determined. No-carrier-added 111In with high specific activity was used in the electrophoretic experiments in ultramicroconcentrations (10(-9)M).
Ivanov
P I
PI
Flerov Laboratory of Nuclear Reaction, JINR, 141980 Dubna, Moscow region, Russian Federation. ivanov@lnr.jinr.ru
Bontchev
G D
GD
Bozhikov
G A
GA
Filossofov
D V
DV
Maslov
O D
OD
Milanov
M V
MV
Dmitriev
S N
SN
D003627:Data Interpretation, Statistical; D004058:Diffusion; D004355:Drug Stability; D004586:Electrophoresis / Q000379:methods; D006863:Hydrogen-Ion Concentration; D007205:Indium Radioisotopes / Q000737:chemistry*; D009994:Osmolar Concentration; D004369:Pentetic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D019275:Radiopharmaceuticals / Q000737:chemistry*; D016008:Statistical Distributions; D013696:Temperature; D013997:Time Factors
D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; D004369:Pentetic Acid