EEMCO guidance for the measurement of skin microcirculation.
The blood supply to the skin is provided by a network of arterioles, capillaries and venules organized into a superficial and a deep plexus. The assessment of skin microcirculation is of valuable interest in cosmetology in the quantification of the sun protection factor, skin irritation and efficacy of antiredness treatments. Skin microcirculation can be measured by means of different techniques, based mainly on the quantification of optical and thermal properties of the skin which are modified by the amount of blood perfusion. Relevant and reproducible data can be obtained only through the understanding of the biophysical background of the technique(s) utilized. Standardization of measuring conditions and procedures is particularly required for blood flow assessment. In this paper, the advantages and disadvantages of the main techniques in use are discussed, and optimization of measurements for laser Doppler techniques is described.
Berardesca
Enzo
E
San Gallicano Dermatological Institute, Rome, Italy.
Lévêque
Jean-Luc
JL
Masson
Philippe
P
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D004345:Drug Industry / Q000379:methods / Q000592:standards; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods* / Q000592:standards*; D008833:Microcirculation / Q000502:physiology; D017156:Photoplethysmography / Q000379:methods / Q000592:standards; D012867:Skin / Q000098:blood supply*; D013817:Thermography / Q000379:methods / Q000592:standards