Early clinical development of pharmaceuticals for type 2 diabetes mellitus: from preclinical models to human investigation.
Wagner
John A
JA
Department of Clinical Pharmacology, Merck Research Laboratories, Rahway, New Jersey 07065, USA. wagner@merck.com
D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000378:metabolism; D004345:Drug Industry; D005947:Glucose / Q000502:physiology; D006801:Humans; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D015398:Signal Transduction
D007328:Insulin; D005947:Glucose