title: Capgras' syndrome in dementia with Lewy bodies.
abstract: We report the occurrence of Capgras' syndrome, or the delusion of doubles, in a patient with dementia with Lewy bodies. The patient believed that several similar-looking impostors had replaced his wife of over 50 years. Uncharacteristically, he adopted a friendly attitude with these impostors. This unusual convivial reaction to the impostors may result from differential involvement of the dual visual pathways processing facial recognition and emotional responses to faces. The delusion resolved spontaneously, coincident with worsening of the dementia. In a retrospective chart review of 18 autopsy-confirmed cases of dementia with Lewy bodies, delusions were reported in 5 subjects (27.8%), of whom 1 had misidentification delusions much like Capgras' syndrome.
authors.affiliation: Greenwich High School, Greenwich, Connecticut, USA.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Marantz
authors.forename: Joe
authors.initials: J
authors.lastname: Verghese
mesh_terms: D000368:Aged; D002194:Capgras Syndrome / Q000209:etiology* / Q000473:pathology / Q000523:psychology; D003702:Delusions / Q000150:complications; D003704:Dementia / Q000150:complications* / Q000473:pathology; D006801:Humans; D020961:Lewy Body Disease / Q000150:complications / Q000473:pathology; D008297:Male