title: [Cutaneous involvement as the form of presentation in B-cell lymphoblastic leukemia/lymphoma].
abstract: Primary cutaneous involvement in B-cell lymphoblastic leukemia/lymphoma is rare in childhood. We present the case of an eleven and a half year old girl who, five months prior to being referred to our center, had undergone surgery to remove a small gluteal tumor diagnosed histopathologically as lymphoid proliferation suggestive of large cell lymphoma. On examination the presence of small nodes close to the scar where the tumor had previously been removed was observed. Hemogram revealed 2.7 x 9/l white blood cells with 0.5 x 9/l neutrophils; the remaining series and complementary investigations were normal. Bone marrow aspiration revealed 52 % blastic cells with immunophenotype and morphological characteristics of common (B-cell) acute lymphoblastic leukemia with L2 subtype in the French-American-British (FAB) classification. Ten months after finishing polychemotherapy, the patient is now in complete remission. We would like to highlight that a small slow-growing cutaneous node could be the presenting form of lymphoblastic lymphoma or acute lymphoblastic leukemia.
authors.affiliation: Servicios de Pediatría (Unidad de Oncohematología Pediátrica). Hospital Universitario de Canarias. La Laguna. Tenerife. España.
authors.forename: R
authors.initials: R
authors.lastname: López Almaraz
authors.forename: J M feminine
authors.initials: JM
authors.lastname: Raya Sánchez
authors.forename: M
authors.initials: M
authors.lastname: Domínguez Suárez
authors.forename: M feminine L
authors.initials: Mf
authors.lastname: Brito Barroso Mf
authors.forename: J
authors.initials: J
authors.lastname: Rodríguez Luis
mesh_terms: D001402:B-Lymphocytes; D006801:Humans; D016130:Immunophenotyping; D016393:Lymphoma, B-Cell; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy