[A case of acute renal failure with marked hyperuricemia developing during mizoribine administration].
A 50-year-old man diagnosed as having AGA(Churg-Strauss syndrome) was administered steroid. After treatment with mizoribine, hyperuricemia and acute renal failure occurred as side effects of this drug. Accordingly we started dialysis treatment, terminated mizoribine treatment, and administered allopurinol dosage. Hemodialysis was necessary every day for 11 days and his renal function recovered after one month. In 67Ga scintigraphy, accumulation of 67Ga was seen in the kidney.
Kushihata
Shigeyuki
S
JA Hiroshima General Hospital, Japan.
Hirabayashi
Akira
A
Sekiguchi
Yoshitaka
Y
Nagai
Kenichi
K
Arata
Toshihiko
T
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000628:therapy; D000493:Allopurinol / Q000627:therapeutic use; D015267:Churg-Strauss Syndrome / Q000188:drug therapy; D006801:Humans; D033461:Hyperuricemia / Q000139:chemically induced* / Q000628:therapy; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012263:Ribonucleosides / Q000009:adverse effects*; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D012263:Ribonucleosides; C010052:mizoribine; D000493:Allopurinol