Electro-oculographic abnormality in eyes with uveal melanoma.
OBJECTIVE
To seek out correlations between preoperative electro-oculogram (EOG) recordings with different types of uveal melanomas, after surgery.


METHODS
We analysed the EOG recordings of 120 patients with uveal melanomas, histologically verified, 100 in the choroid and 20 in the iris and ciliary body. The EOG data were correlated with the site, size and histological type of the tumor.


RESULTS
In 100 eyes with choroidal melanoma the Arden Index (AI) was less than in fellow eyes (mean 126.6, SD +/- 23.8 and 202.9, SD +/- 47.0; p=0.01). The EOG values were not different with respect to the histological type, site and size of tumor. In cases with iris and ciliary body melanomas the AI were not significantly different from the fellow eyes (mean 180.6, SD +/- 23.6 and 203.2, SD +/- 38.7; p=0.07).


CONCLUSIONS
Since the EOG is abnormal in eyes with choroidal melanoma, it can be considered a powerful auxiliary for diagnosing these tumors.
Spadea
L
L
Eye Clinic, University of L'Aquila, L'Aquila, Italy. lspadea@cc.univaq.it
Bianco
G
G
Magni
R
R
Rinaldi
G
G
Ponte
F
F
Brancato
R
R
Ravalico
G
G
Balestrazzi
E
E
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002830:Choroid Neoplasms / Q000175:diagnosis; D002924:Ciliary Body; D004585:Electrooculography; D006801:Humans; D015811:Iris Neoplasms / Q000175:diagnosis; D008545:Melanoma / Q000175:diagnosis*; D008875:Middle Aged; D014604:Uveal Neoplasms / Q000175:diagnosis*