Why have we failed to find the low penetrance genetic constituents of common cancers?
Caporaso
Neil E
NE
Genetic Epidemiology Branch, National Cancer Institute, Rockville, Maryland 20892, USA.
D005260:Female; D008040:Genetic Linkage; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D008297:Male; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D009386:Neoplastic Syndromes, Hereditary / Q000453:epidemiology / Q000235:genetics*; D019683:Penetrance; D010641:Phenotype; D015995:Prevalence; D012106:Research; D018570:Risk Assessment; D012680:Sensitivity and Specificity