Peritumoral rim enhancement of liver metastasis: hemodynamics observed on single-level dynamic CT during hepatic arteriography and histopathologic correlation.
OBJECTIVE
The purpose of this work was to clarify the mechanism of peritumoral rim enhancement of metastatic liver cancer.


METHODS
Twenty-nine liver metastases of colon cancer were examined by single-level dynamic CT during hepatic arteriography, which was performed without table feed. We analyzed these findings and correlated them with the histopathologic findings.


RESULTS
Eleven metastases were hypervascular and 18 were hypovascular. Early appearance of rim enhancement was seen in 3 of 10 hypervascular metastases and 17 of 18 hypovascular metastases (p < 0.01). The time of appearance and thickness of peritumoral rim enhancement showed no apparent correlation with the desmoplastic reaction or inflammation in the surrounding hepatic parenchyma.


CONCLUSIONS
Two types of intra- and peritumoral enhancement were observed. Peritumoral rim enhancement was considered to be due mainly to the drainage of blood flow from the tumor to the surrounding hepatic parenchyma in hypervascular metastasis or increased arterioportal shunts surrounding the tumor in hypovascular metastasis.
Terayama
Noboru
N
Department of Radiology, Kanazawa University School of Medicine, Kanazawa 920-8641, Japan. tera@rad.m.kanazawa-u.ac.jp
Matsui
Osamu
O
Ueda
Kazuhiko
K
Kobayashi
Satoshi
S
Sanada
Junichiro
J
Gabata
Toshifumi
T
Kawamori
Yasuhiro
Y
Kadoya
Masumi
M
D000792:Angiography / Q000379:methods; D003110:Colonic Neoplasms / Q000473:pathology*; D005260:Female; D006439:Hemodynamics; D006499:Hepatic Artery / Q000000981:diagnostic imaging*; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply* / Q000556:secondary*; D008297:Male; D012039:Regional Blood Flow; D014057:Tomography, X-Ray Computed / Q000379:methods*