Cytological features of chronic follicular cervicitis in liquid-based specimens: a potential diagnostic pitfall.
A review of negative split-sample cervical cytology cases revealed five cases reported as chronic follicular cervicitis. These cases showed characteristic morphological features in conventional smears with lymphoid cells, plasma cells and tingible body macrophages smeared across the slides. This contrasts with the presentation of ThinPrep samples (Cytic Corporation, Boxburgh, MA, USA), where cells were observed aggregated in clumps. The different presentation noted in liquid-based samples may require careful microscopic evaluation at high-power magnification.
Halford
J A
JA
Cytology Department, Queensland Medical Laboratory, Brisbane, Qld, Australia. halfordja@qml.com.au
D000328:Adult; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008223:Lymphoma / Q000473:pathology; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D002575:Uterine Cervicitis / Q000473:pathology*; D014626:Vaginal Smears