Molecular modeling the human A1 adenosine receptor and study of the mechanisms of its selective ligand binding.
Ivanov
A A
AA
Department of Chemistry, Moscow State University, Vorob'evy gory, Moscow, 119992 Russia.
Baskin
I I
II
Palyulin
V A
VA
Zefirov
N S
NS
D000241:Adenosine / Q000031:analogs & derivatives / Q000378:metabolism; D000595:Amino Acid Sequence; D001665:Binding Sites; D001667:Binding, Competitive; D006801:Humans; D007700:Kinetics; D008024:Ligands; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011485:Protein Binding; D017433:Protein Structure, Secondary; D058915:Purinergic P1 Receptor Antagonists; D018047:Receptors, Purinergic P1 / Q000737:chemistry* / Q000378:metabolism*; D017386:Sequence Homology, Amino Acid; D014970:Xanthines / Q000378:metabolism
D008024:Ligands; D058915:Purinergic P1 Receptor Antagonists; D018047:Receptors, Purinergic P1; D014970:Xanthines; C058394:2-chloro-N(6)cyclopentyladenosine; C051360:1,3-dipropyl-8-cyclopentylxanthine; D000241:Adenosine