title: Prehospital care of the patient with major trauma.
abstract: Recent research efforts have demonstrated that many longstanding practices for the prehospital resuscitation of trauma patients may be inappropriate under certain circumstances. For example, traditional practices, such as application of anti-shock garments and i.v. fluid administration to raise blood pressure, may even be detrimental in certain patients with uncontrolled bleeding, particularly those with penetrating injuries. ETI, although potentially capable of transiently prolonging a patient's ability to tolerate circulatory arrest, may also be harmful if overzealous PPV further compromises cardiac output, particularly in those patients with severe hemodynamic instability. In addition, if these procedures delay patient transport, any benefit that they may offer could be outweighed by the delay in definitive care. Although traditionally taught to "hyperventilate" the patient with severe head injury, current recommendations are to avoid this tactic unless there is evidence of herniation. Even time-honored traditions, such as universal spinal precautions and CPR during circulatory arrest, are being scrutinized [2,134]. Further prospective randomized clinical trials are needed to better define the role of many overlapping therapies in prehospital trauma care. Such research must specifically address and stratify the different mechanisms of injury, anatomic areas involved, and the physiologic staging of the injury. Furthermore, the efficacy of a single intervention may be masked by a confounding variable [5]. For example, a trial of an effective new HBOC in moribund patients that indicates no advantage in the study results may have been confounded by overzealous PPV, which may have led to suboptimal outcomes. It is hoped that, in the future, EMS physicians will be able to not only better discriminate in their management of patients with major trauma but also improve outcomes as a result.
authors.affiliation: University of Texas Southwestern Medical Center, Parkland Health and Hospital System, Dallas Metropolitan Biotel (EMS) System, Emergency Medicine, MC 8579, 5323 Harry Hines Boulevard, Dallas, TX 75390-8579, USA.
authors.forename: Raymond
authors.initials: R
authors.lastname: Fowler
authors.forename: Paul E
authors.initials: PE
authors.lastname: Pepe
mesh_terms: D006259:Craniocerebral Trauma / Q000628:therapy; D004632:Emergency Medical Services; D005440:Fluid Therapy; D006323:Heart Arrest / Q000209:etiology / Q000628:therapy*; D006470:Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D012138:Respiratory Therapy / Q000379:methods; D012771:Shock, Hemorrhagic / Q000517:prevention & control; D014947:Wounds and Injuries / Q000150:complications / Q000628:therapy*