Enzyme inhibition-based biosensors and biosensing systems: questionable analytical devices.
An overview of methods based on enzyme inhibition is presented. Both biosensors and biosensing systems (implemented in continuous and discontinuous approaches) are considered. The aim of the overview is to alert users on the use of these devices which, despite they can involve selective biocatalysts, the inhibition effect is not selective. Tables and examples illustrate this assertion.
Luque de Castro
M D
MD
Analytical Chemistry Division, Annex C-3 Faculty of Sciences, Campus of Rabanales, University of Córdoba, E-14071 Córdoba, Spain. qallucam@uco.es
Herrera
M C
MC
D015374:Biosensing Techniques / Q000145:classification / Q000295:instrumentation* / Q000379:methods*; D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods; D004791:Enzyme Inhibitors / Q000737:chemistry*; D004798:Enzymes; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013673:Technology Assessment, Biomedical / Q000379:methods*; D014159:Transducers
D004791:Enzyme Inhibitors; D004798:Enzymes