[Nitric oxide and cytokine levels in the seminal plasma of infertile men].
OBJECTIVE
To evaluate the effect of nitric oxide (NO), TNF alpha, IL-6, IL-8 on the pathogenesis of infertile men.


METHODS
NO, TNF alpha, IL-6 and IL-8 levels were assayed in 80 infertile men and 26 normal men.


RESULTS
The levels of NO, TNF alpha, IL-6 and IL-8 in infertile men were all significantly higher than those in controls (P < 0.01 or P < 0.05). NO was positively correlated with TNF alpha, IL-6 and IL-8 (P < 0.01).


CONCLUSIONS
NO, TNF alpha, IL-6 and IL-8 might play an important role in the pathogenic process of infertile.
Wu
Hong
H
Department of Urology, Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China.
D000328:Adult; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D007248:Infertility, Male / Q000378:metabolism*; D015850:Interleukin-6 / Q000378:metabolism; D016209:Interleukin-8 / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009569:Nitric Oxide / Q000378:metabolism*; D012661:Semen / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D016207:Cytokines; D015850:Interleukin-6; D016209:Interleukin-8; D014409:Tumor Necrosis Factor-alpha; D009569:Nitric Oxide