[Clinical and pathological investigation of polymyositis and dermatomyositis: report of 83 cases].
OBJECTIVE
To study the clinical and pathological characteristics and treatment of polymyositis (PM) and dermatomyositis (DM).


METHODS
Eighty-three DM/PM cases were reviewed and analyzed.


RESULTS
The main clinical presentations of PM/DM included amyosthenia, muscular tenderness, elevation of serum enzymes, accompanied by abnormal electromyography and muscular pathology. A total efficacy rate of 86.7% was achieved after treatment with corticosteroid and immuno- depressants.


CONCLUSIONS
The different clinical and pathological presentations of various types of PM/DM suggest different pathogenesis between DM and PM. Nerve damage is a part of the systemic damages due to the disease, the prognosis of which is related to its classification and then timing of the treatment. Early effective treatment can improve the prognosis.
Li
Qiang
Q
Department of Neurology, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China.
Lu
Bing-Xun
BX
Zhou
Liang
L
An
Sheng-Li
SL
D000293:Adolescent; D000328:Adult; D000368:Aged; D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis; D002648:Child; D003882:Dermatomyositis / Q000188:drug therapy / Q000276:immunology / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D017285:Polymyositis / Q000188:drug therapy / Q000276:immunology / Q000473:pathology / Q000503:physiopathology*; D011379:Prognosis; D016896:Treatment Outcome
D001323:Autoantibodies; D007166:Immunosuppressive Agents