Purpura fulminans and anticardiolipin antibodies in a patient with Grave's disease.
We describe a patient with Grave's discase who developed purpura fulminans and who was found to have anticardiolipin antibodies after being started on propylthiouracil (PTU). We discuss the potential role of the antiphospholipid antibody in this woman's presentation, and its association to both PTU and autoimmune thyroid disease.
Ligier
Sophie
S
Division de Rhumatologie, Hôpital Maisonneuve-Rosemont, Université de Montreal, Canada.
Pham
Cuong D
CD
Watters
A Kevin
AK
Kassis
Jeannine
J
Fortin
Paul R
PR
D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000032:analysis / Q000276:immunology*; D013956:Antithyroid Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006111:Graves Disease / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D006801:Humans; D011695:IgA Vasculitis / Q000139:chemically induced* / Q000473:pathology; D011441:Propylthiouracil / Q000009:adverse effects* / Q000627:therapeutic use
D017153:Antibodies, Anticardiolipin; D013956:Antithyroid Agents; D011441:Propylthiouracil