title: Hereditary chin trembling: a new family with exclusion of the chromosome 9q13-q21 Locus.
abstract: Hereditary chin trembling is a rare autosomal dominant condition that has been linked to chromosome 9q13-21 in one kindred. We describe a four-generation family with this condition and, using linkage analysis, have excluded the 9q13-21 region as causing the chin trembling in this family.
authors.affiliation: Ottawa Health Research Institute, Ottawa, Canada. dagrimes@ottawahospital.on.ca
authors.forename: David A
authors.initials: DA
authors.lastname: Grimes
authors.forename: Fabin
authors.initials: F
authors.lastname: Han
authors.forename: Dennise
authors.initials: D
authors.lastname: Bulman
authors.forename: Mary Lou
authors.initials: ML
authors.lastname: Nicolson
authors.forename: Oksana
authors.initials: O
authors.lastname: Suchowersky
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage; D002680:Chin / Q000294:innervation*; D002874:Chromosome Mapping; D002899:Chromosomes, Human, Pair 9; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D014202:Tremor / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*
chemical_list: D019274:Botulinum Toxins, Type A