title: Peripheral retinoschisis and exudative retinal detachment in pars planitis.
abstract: OBJECTIVE
  To review and describe bullous retinoschisis and exudative retinal detachment in patients with pars planitis.
  
  
  METHODS
  Retrospective, multicenter study of patients with pars planitis who presented with retinoschisis and exudative retinal detachments.
  
  
  RESULTS
  The authors describe 13 eyes of 9 patients with pars planitis who presented with inferior peripheral retinoschisis and/or exudative retinal detachment. Four patients were male; five were female. Patients' ages ranged from 8 years to 35 years (median, 12 years). The follow-up interval ranged from 1 month to 10 years (median, 4 years). These peripheral retinal elevations had a tendency to remain stable, although those with telangiectatic vessels or vasoproliferative tumors occasionally demonstrated an increase in accumulation of exudate. Treatment of such eyes with cryotherapy, or low-dose plaque radiotherapy, resulted in vasoproliferative tumor and telangiectatic vessel regression, absorption of the hard exudate, and resolution of the retinal elevation in four of five eyes. One patient had spontaneous regression of the retinoschisis cavity over a 4-year period.
  
  
  CONCLUSIONS
  Patients with pars planitis may present with bullous retinoschisis and/or exudative retinal detachment. These findings may be related to a Coats disease-like vascular response (telangiectatic vessels and vasoproliferative tumors) secondary to chronic inflammation. Treatment of the vascular leakage tended to result in resolution of the detachment and/or schisis.
authors.affiliation: California Pacific Medical Center, San Francisco, CA, USA.
authors.forename: Aryeh L
authors.initials: AL
authors.lastname: Pollack
authors.forename: H Richard
authors.initials: HR
authors.lastname: McDonald
authors.forename: Robert N
authors.initials: RN
authors.lastname: Johnson
authors.forename: Everett
authors.initials: E
authors.lastname: Ai
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Irvine
authors.forename: J Michael
authors.initials: JM
authors.lastname: Lahey
authors.forename: Hilel
authors.initials: H
authors.lastname: Lewis
authors.forename: Alvaro
authors.initials: A
authors.lastname: Rodriguez
authors.forename: Edwin H
authors.initials: EH
authors.lastname: Ryan
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
mesh_terms: D000293:Adolescent; D000328:Adult; D001918:Brachytherapy; D002648:Child; D017679:Cryotherapy; D005122:Exudates and Transudates; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D015868:Pars Planitis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D041441:Retinoschisis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012189:Retrospective Studies; D014792:Visual Acuity