Facile and highly stereoselective synthesis of the tetracyclic erythrinane core.
A highly stereoselective synthesis of the tetracyclic core of the Erythrina alkaloids is reported through the application of a Meyers bicyclic lactam template.
Allin
Steven M
SM
Department of Chemistry, Loughborough University, Loughborough, Leicestershire LE11 3TU, England. s.m.allin@lboro.ac.uk
James
Stella L
SL
Elsegood
Mark R J
MR
Martin
William P
WP
D000470:Alkaloids / Q000138:chemical synthesis*; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D004895:Erythrina / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000470:Alkaloids