title: Pair-wise linear and 3D nonlinear relationships between the liver antioxidant enzyme activities and the rate of body oxygen consumption in mice.
abstract: Relationships between the rate of body oxygen consumption (VO2) and the liver key antioxidant enzyme activities were assessed in female CBA mice. The pair-wise linear regression and correlation demonstrated significant correlative links between VO2 and activity of catalase (CAT). Nonlinear 3D plotting revealed a complementary pattern of CAT and glutathione peroxidase (GP) relation. CAT activity was elevated in mice with proportionally high VO2 and superoxide dismutase (SOD), whereas GP activity was high in animals with low or disproportional VO2 and SOD.
authors.affiliation: Department of Physiology, Institute of Gerontology, Academy of Medical Sciences of Ukraine, Kiev, Ukraine. tamur@carrier.kiev.ua
authors.forename: Khachik K
authors.initials: KK
authors.lastname: Muradian
authors.forename: Natalie A
authors.initials: NA
authors.lastname: Utko
authors.forename: Tatyana G
authors.initials: TG
authors.lastname: Mozzhukhina
authors.forename: Alexander Y
authors.initials: AY
authors.lastname: Litoshenko
authors.forename: Irina N
authors.initials: IN
authors.lastname: Pishel
authors.forename: Vladislav V
authors.initials: VV
authors.lastname: Bezrukov
authors.forename: Vadim E
authors.initials: VE
authors.lastname: Fraifield
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism*; D005260:Female; D005979:Glutathione Peroxidase / Q000378:metabolism*; D016014:Linear Models; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D051379:Mice; D008808:Mice, Inbred CBA; D017711:Nonlinear Dynamics; D010101:Oxygen Consumption; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D000975:Antioxidants; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase