title: Estrogenic/antiestrogenic activity of homoisoflavonoids from bulbs of Muscari racemosum (L.) Miller.
abstract: The homoisoflavonoid fraction obtained from the Muscari racemosum bulb ether extract (MRBEE) exhibited estrogenic activity by inducing proliferation of MCF7 cells in a dose-dependent manner. In the presence of estradiol MRBEE exhibited a dose-dependent antiestrogenic activity.
authors.affiliation: Department of Toxicology and Xenobiotics, Institute of Preventive and Clinical Medicine, Bratislava 83301, Slovakia. urbancik@upkm.sk
authors.forename: M
authors.initials: M
authors.lastname: Urbancíková
authors.forename: I
authors.initials: I
authors.lastname: Masterová
authors.forename: J
authors.initials: J
authors.lastname: Tóth
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology; D002455:Cell Division / Q000187:drug effects; D020847:Estrogen Receptor Modulators / Q000302:isolation & purification / Q000494:pharmacology*; D004967:Estrogens / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D007529:Isoflavones / Q000302:isolation & purification* / Q000494:pharmacology*; D019668:Liliaceae / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: D020847:Estrogen Receptor Modulators; D004967:Estrogens; D007529:Isoflavones