The role of Mcl-1 and Bax expression alteration in the decreased rescue of human neutrophils from apoptosis by GM-CSF with aging.
Fulop
Tamas
T
Institut Unversitiare de Gériatire de Sherbrooke, Center on Aging Research, Department of Medicine, Service de Gériatrie, Faculty of Medicine, Université de Shebrooke, Sherbrooke, Quebec J1H 4C4, Canada.
Larbi
Anis
A
Linteau
Annie
A
Desgeorges
Sebastien
S
Douziech
Nadine
N
D000375:Aging / Q000187:drug effects / Q000502:physiology*; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D016922:Cellular Senescence / Q000187:drug effects / Q000502:physiology*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000494:pharmacology*; D006801:Humans; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D009363:Neoplasm Proteins / Q000235:genetics*; D009504:Neutrophils / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D019253:Proto-Oncogene Proteins c-bcl-2; D051028:bcl-2-Associated X Protein
C494826:BAX protein, human; D064549:Myeloid Cell Leukemia Sequence 1 Protein; D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D051028:bcl-2-Associated X Protein; D016178:Granulocyte-Macrophage Colony-Stimulating Factor