title: [Geographic approach in malaria control in the central highlands of Madagascar].
abstract: Following the severe malaria outbreak in the central highlands in Madagascar in 1986, a vector control program by use DDT pm 75 house-spraying has been implemented to operate in areas located at altitudes between 1000 and 1500 m. Early treatment with chloroquine has also been incorporated in the control program. To detect areas at particular high risk for malaria outbreak the Geographic Information System (GIS) has been applied and tested. The study has shown that the system can be used in malaria surveillance in order to identify areas in which an intense distribution of Anopheles funestus can be anticipated and, hence, targeted in spraying campaigns. The system may also be used to monitor changes in anti-malarial drug resistance, in addition, to control of other vector-born diseases.
authors.affiliation: Institut Pasteur de Madagascar, BP 1274, 101 Antananarivo, Madagascar.
authors.forename: F
authors.initials: F
authors.lastname: Rakotomanana
authors.forename: I
authors.initials: I
authors.lastname: Jeanne
authors.forename: J B
authors.initials: JB
authors.lastname: Duchemin
authors.forename: V
authors.initials: V
authors.lastname: Pietra
authors.forename: L
authors.initials: L
authors.lastname: Raharimalala
authors.forename: M L
authors.initials: ML
authors.lastname: Tombo
authors.forename: F
authors.initials: F
authors.lastname: Ariey
mesh_terms: D000531:Altitude; D000818:Animals; D000852:Anopheles / Q000469:parasitology; D000962:Antimalarials / Q000627:therapeutic use; D002738:Chloroquine / Q000627:therapeutic use; D003634:DDT; D004196:Disease Outbreaks / Q000517:prevention & control* / Q000706:statistics & numerical data; D004351:Drug Resistance; D019353:Endemic Diseases / Q000517:prevention & control / Q000706:statistics & numerical data; D040362:Geographic Information Systems / Q000458:organization & administration*; D006798:Housing; D006801:Humans; D007303:Insect Vectors / Q000382:microbiology / Q000469:parasitology; D008270:Madagascar / Q000453:epidemiology; D008288:Malaria / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D009032:Mosquito Control / Q000379:methods*; D011159:Population Surveillance / Q000379:methods*; D012307:Risk Factors; D012621:Seasons
chemical_list: D000962:Antimalarials; D002738:Chloroquine; D003634:DDT