Sequence relationships in the legume lectin fold and other jelly rolls.
Distant sequence relationships in proteins containing the beta jelly-roll fold were investigated using sensitive sequence comparison methods, including PSI-BLAST and Hidden Markov Models. A relationship was identified between the rmlC-like and phosphomannose isomerase SCOP (version 1.53) superfamilies, which were merged in the most recent SCOP release. No other distant sequence relationships linking jelly roll superfamilies were found.
Williams
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School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.
Westhead
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D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D002238:Carbohydrate Epimerases / Q000737:chemistry* / Q000145:classification; D002241:Carbohydrates / Q000737:chemistry; D007887:Fabaceae / Q000737:chemistry*; D008359:Mannose-6-Phosphate Isomerase / Q000737:chemistry* / Q000145:classification; D008958:Models, Molecular; D008969:Molecular Sequence Data; D037121:Plant Lectins / Q000737:chemistry* / Q000235:genetics; D017510:Protein Folding; D017433:Protein Structure, Secondary; D015203:Reproducibility of Results; D017386:Sequence Homology, Amino Acid; D013329:Structure-Activity Relationship; D001426:Bacterial Proteins; D002237:Carbohydrate Dehydrogenases
D002238:Carbohydrate Epimerases; D002241:Carbohydrates; D008359:Mannose-6-Phosphate Isomerase; D037121:Plant Lectins; C020092:dTDP-4-ketorhamnose 3,5-epimerase; D001426:Bacterial Proteins; D002237:Carbohydrate Dehydrogenases