Mammalian septins nomenclature.
There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct names given to splice variants of the same gene. Moreover, some names are based on those of yeast or Drosophila septins that are not the closest homologues. Therefore, we suggest that the mammalian septin field adopt a common nomenclature system, based on that adopted by the Mouse Genomic Nomenclature Committee and accepted by the Human Genome Organization Gene Nomenclature Committee. The human and mouse septin genes will be named SEPT1-SEPT10 and Sept1-Sept10, respectively. Splice variants will be designated by an underscore followed by a lowercase "v" and a number, e.g., SEPT4_v1.
Macara
Ian G
IG
Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA. igm9c@virginia.edu
Baldarelli
Richard
R
Field
Christine M
CM
Glotzer
Michael
M
Hayashi
Yasuhide
Y
Hsu
Shu-Chan
SC
Kennedy
Mary B
MB
Kinoshita
Makoto
M
Longtine
Mark
M
Low
Claudia
C
Maltais
Lois J
LJ
McKenzie
Louise
L
Mitchison
Timothy J
TJ
Nishikawa
Toru
T
Noda
Makoto
M
Petty
Elizabeth M
EM
Peifer
Mark
M
Pringle
John R
JR
Robinson
Phillip J
PJ
Roth
Dagmar
D
Russell
S E Hilary
SE
Stuhlmann
Heidi
H
Tanaka
Manami
M
Tanaka
Tomoo
T
Trimble
William S
WS
Ware
Jerry
J
Zeleznik-Le
Nancy J
NJ
Zieger
Barbara
B
D017398:Alternative Splicing; D000818:Animals; D003598:Cytoskeletal Proteins; D005656:Fungal Proteins / Q000235:genetics; D020558:GTP Phosphohydrolases / Q000145:classification* / Q000235:genetics; D019204:GTP-Binding Proteins / Q000235:genetics; D006801:Humans; D010802:Phylogeny; D017434:Protein Structure, Tertiary; D058112:Septins; D009626:Terminology as Topic
D003598:Cytoskeletal Proteins; D005656:Fungal Proteins; C410684:PCD1 protein, Pyrenopeziza brassicae; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins; C436485:SEPTIN6 protein, human; C486672:Sept6 protein, mouse; D058112:Septins; C407343:septin 3