The effect of Alkanna tinctoria Tausch on burn wound healing in rabbits.
Eighteen adult male New Zealand White rabbits were used in the treatment of partial thickness, severe and olive oil burns. Both right and left sides of the animals were burned to make partial thickness, severe and hot olive oil burn wounds. The solution of A. tinctoria TAUSCH in 16% prepared in medical olive oil in weight basis, were applied to the left, and right side served as control. It was topically applied twice a day by gently rubbing against the burn area. While complete healing of partial thickness and olive oil burn wounds occurred in 7 to 10, and 26 days, respectively, with well formed dermal-epidermal junctions in both groups, severely burned wounds appeared to be nonresponsive to A. tinctoria.
Ogurtan
Z
Z
Department of Surgery, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkey. zogurtan@selcuk.edu.tr
Hatipoglu
F
F
Ceylan
C
C
D000287:Administration, Topical; D000818:Animals; D028082:Boraginaceae; D002056:Burns / Q000188:drug therapy / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D008517:Phytotherapy / Q000662:veterinary*; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D011817:Rabbits; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects*
D010936:Plant Extracts