Non-linear behaviour of respiratory movement in obstructive sleep apnoea syndrome.
In this study we investigated the non-linear properties of respiratory movement in patients with obstructive sleep apnoea syndrome (OSAS) during sleep without and with nasal continuous positive airway pressure (nCPAP). To calculate the correlation dimension (D2) in respiratory movement we applied an algorithm proposed by Grassberger and Procaccia. Non-linearity in respiratory movement was tested by comparing D2 for the original data with that for surrogate data. Respiratory movement was recorded from 10 patients with OSAS. D2 during both wakefulness with eyes closed and during sleep with nCPAP at 8 cm H2O could be computed in all subjects (2.50 +/- 0.69 and 1.68 +/- 0.17, respectively). On the other hand, D2 during sleep with apnoea could not be computed in patients with severe OSAS. These results indicate the abnormal properties of respiratory movement during apnoeic sleep in severe OSAS. Moreover, respiratory movement with nCPAP was shown to be non-linear deterministic behaviour in respiratory movement during sleep. Analysis of D2 for respiratory movement may be useful in adjusting (titrating) nCPAP and classifying severity in OSAS.
Miyata
Masanori
M
Third Department of Internal Medicine, Faculty of Medicine, Tottori University, Nishimachi, Yonago, Japan.
Burioka
Naoto
N
Suyama
Hisashi
H
Sako
Takanori
T
Nomura
Takashi
T
Takeshima
Takao
T
Higami
Shigeru
S
Shimizu
Eiji
E
D000328:Adult; D000465:Algorithms; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D017711:Nonlinear Dynamics; D015656:Respiratory Mechanics / Q000502:physiology*; D012890:Sleep; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology*; D014851:Wakefulness