Breast cancer in the very young patient: a multidisciplinary case presentation.
A case is presented that exemplifies many issues and controversies in the diagnosis and treatment of breast cancer in the very young. This woman was 22 years of age at diagnosis; she initially underwent breast-conservation therapy and adjuvant chemotherapy, retained fertility, had a subsequent uncomplicated pregnancy and delivery, and 7 years later developed a local recurrence in the breast. The discussion addresses risk factors, diagnosis, and treatment of breast cancer in the young; the impact of treatment on fertility; implications regarding pregnancy, and the management of local recurrence after breast conservation.
Mintzer
David
D
Joan Karnell Cancer Center, Pennsylvania Hospital, 230 West Washington Square, Philadelphia, PA 19106, USA. mintzerd@pahosp.com
Glassburn
John
J
Mason
Bernard A
BA
Sataloff
Dahlia
D
D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D002114:Calcinosis; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local; D012307:Risk Factors; D013524:Surgical Flaps