title: Current management of interstitial cystitis.
abstract: The management of patients with IC remains a challenge because no single agent has proven universally effective. DMSO and PPS have been evaluated through early placebo-controlled trials, and these two agents are FDA approved treatments for IC. BCG is currently undergoing a large placebo-controlled trial, and hyaluronic acid is receiving similar clinical evaluation. Sacral nerve root stimulation shows promise with early favorable results. As with any treatment algorithm, it is reasonable to begin with conservative treatment using time-dependent milestones, allowing adequate trials of successive therapy while ensuring an appropriate pace for timely symptom resolution.
authors.affiliation: Graduate Hospital, 1800 Lombard Street, Pepper Pavilion, Suite 900, Philadelphia, PA 19146, USA. jlukban@aol.com
authors.forename: James Chivian
authors.initials: JC
authors.lastname: Lukban
authors.forename: Kristene E
authors.initials: KE
authors.lastname: Whitmore
authors.forename: Grannum R
authors.initials: GR
authors.lastname: Sant
mesh_terms: D018856:Cystitis, Interstitial / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans