title: [Heterotopic ossification and brain injury].
abstract: OBJECTIVE
  The aim of the study was to evaluate the incidence and the risk factors of heterotopic ossifications in patients with severe traumatic brain injury.
  
  
  METHODS
  This retrospective study was conducted in a sample of 86 patients during a two years period. These patients were receiving care in an acute rehabilitation setting designed for traumatic brain injury patients emerging from coma. The statistical analysis used chi(2) and Fisher tests.
  
  
  RESULTS
  Forty-nine heterotopic ossifications were observed in 24 patients (incidence 28.57%, 2.04/patient). Most of them were localised at the level of the hip, of the elbow and of the knee. No significant relation was found between heterotopic ossification and sex, age, clinical severity, motor impairment, spasticity or autonomic dysreflexia. On the contrary, associated limb fractures, specially when requiring a surgical treatment, were found to be correlated to a greater incidence of heterotopic ossification.
  
  
  CONCLUSIONS
  Some of the risk factors observed in the present study were in accordance with those previously described in the literature. This work shows the difficult place of the initial care of patients with severe traumatic brain injury specially during there stay in intensive care units.
authors.affiliation: Service de médecine physique et réadaptation, hôpital d'instruction des armées Laveran, 13998 Marseille Armées, France. cflin@club-internet.fr
authors.forename: C
authors.initials: C
authors.lastname: Flin
authors.forename: H
authors.initials: H
authors.lastname: Curalucci
authors.forename: A
authors.initials: A
authors.lastname: Duvocelle
authors.forename: J M
authors.initials: JM
authors.lastname: Viton
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D004550:Elbow / Q000473:pathology; D005260:Female; D006615:Hip / Q000473:pathology; D006801:Humans; D015994:Incidence; D007717:Knee / Q000473:pathology; D008297:Male; D009999:Ossification, Heterotopic / Q000209:etiology* / Q000473:pathology; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index