Hypersexuality after pallidal surgery in Parkinson disease.
OBJECTIVE
To examine the possible association of neuropsychiatric symptoms and pallidal surgery for Parkinson disease (PD).


BACKGROUND
Parkinson disease may be accompanied by a variety of psychiatric symptoms. It is important to distinguish these from psychiatric syndromes that are associated with the treatment of PD.


METHODS
Case description of a patient with PD and a history of right pallidotomy who developed a psychiatric syndrome, including prominent hypersexuality, after surgical implantation of a deep brain stimulator electrode in the left globus pallidus.


CONCLUSIONS
This case demonstrates that patients receiving antiparkinson medication may be at risk for the development of psychiatric sequelae after pallidal surgery.
Roane
David M
DM
Department of Psychiatry, Beth Israel Medical Center, New York, New York, USA. droane@bethisraelny.org
Yu
Mi
M
Feinberg
Todd E
TE
Rogers
John D
JD
D000978:Antiparkinson Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003024:Clozapine / Q000627:therapeutic use; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D005917:Globus Pallidus / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D010300:Parkinson Disease / Q000150:complications* / Q000503:physiopathology* / Q000628:therapy; D012735:Sexual Dysfunction, Physiological / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed
D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D003024:Clozapine