Left-right asymmetry: all hands to the pump.
How do embryos establish differences between their left and right sides? Previous studies have implicated various signaling molecules and directional beating of cilia. Now, a new player enters the scene: the proton-potassium pump.
Stern
Claudio D
CD
Department of Anatomy & Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. c.stern@ucl.ac.uk
Wolpert
Lewis
L
D000818:Animals; D004292:Dominance, Cerebral; D004625:Embryo, Nonmammalian / Q000502:physiology*; D006801:Humans; D009865:Oocytes / Q000502:physiology*; D014981:Xenopus / Q000196:embryology