Transcription factors do it together: the hows and whys of studying protein-protein interactions.
Protein-protein interactions are intrinsic to virtually every cellular process. Recent breakthroughs in techniques to study protein-interaction and the availability of fully sequenced plant genomes have attracted many plant scientists to undertake the first steps in the field of protein interactions. High-throughput screening systems allow the discovery of protein functions. Even without performing laborious functional assays, in planta functional homologues and redundant proteins can be accurately predicted based on protein-interaction maps. Therefore, protein-protein-interaction screenings are an essential supplement to the current functional-genomics toolbox.
Immink
Richard G H
RG
Business Unit Plant Development and Reproduction, Plant Research International, Bornsesteeg 65, 6708 PD Wageningen, The Netherlands.
Angenent
Gerco C
GC
D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D031541:Fluorescence Resonance Energy Transfer; D026161:MADS Domain Proteins / Q000235:genetics / Q000378:metabolism; D010944:Plants / Q000235:genetics; D011485:Protein Binding; D025941:Protein Interaction Mapping / Q000379:methods*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D020798:Two-Hybrid System Techniques; D015003:Yeasts / Q000235:genetics
D004268:DNA-Binding Proteins; D026161:MADS Domain Proteins; D014157:Transcription Factors