title: Current and future hepatitis C virus diagnostic testing: problems and advancements.
abstract: Serological antibody assays used in hepatitis C virus diagnosis have improved in sensitivity and specificity. However, detection of active viremia or monitoring levels of virus during or after patient treatment is most commonly undertaken using nucleic acid-based technologies. Advancements in diagnostic technologies and implications for managing patients with hepatitis C in various clinical settings are discussed.
authors.affiliation: Department of Laboratory Medicine, University of Washington Medical Center, Seattle, WA 98104-2499, USA.
authors.forename: Ayaz M
authors.initials: AM
authors.lastname: Majid
authors.forename: David R
authors.initials: DR
authors.lastname: Gretch
mesh_terms: D005838:Genotype; D016174:Hepacivirus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006526:Hepatitis C / Q000097:blood / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D011933:Reagent Kits, Diagnostic / Q000639:trends; D012698:Serologic Tests / Q000379:methods / Q000639:trends*; D014766:Viremia / Q000175:diagnosis / Q000821:virology
chemical_list: D018937:Hepatitis C Antibodies; D011933:Reagent Kits, Diagnostic