title: Severe scleritis and urticarial lesions.
abstract: OBJECTIVE
  To report the first known case of bilateral scleritis in a patient with hypocomplementemic urticarial vasculitis.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  Medical and ophthalmic history, results of physical and ophthalmic examinations, laboratory data, and histologic and immunopathologic examination were reviewed and results recorded.
  
  
  RESULTS
  A 67-year-old man who presented with eye redness and pain, rash, arthralgia, and malaise was found to have hypocomplementemic urticarial vasculitis. Treatment with high-dose oral corticosteroids and mycophenolate mofetil resulted in the resolution of the rash and scleritis.
  
  
  CONCLUSIONS
  Ocular involvement may be a helpful clue in the diagnosis of this uncommon syndrome.
authors.affiliation: Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. jthorne@jhmi.edu
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Thorne
authors.forename: Maria I
authors.initials: MI
authors.lastname: Hernandez
authors.forename: Adrienne
authors.initials: A
authors.lastname: Rencic
authors.forename: H Carlos
authors.initials: HC
authors.lastname: Nousari
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000097:blood; D003176:Complement C3 / Q000172:deficiency; D003181:Complement C4 / Q000172:deficiency; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D015423:Scleritis / Q000150:complications*; D014581:Urticaria / Q000150:complications*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000974:Antibodies, Antinuclear; D003176:Complement C3; D003181:Complement C4; D005938:Glucocorticoids; D009173:Mycophenolic Acid; D011241:Prednisone