title: A simple scheme for the design of solvent-suppression pulses.
abstract: Excitation sculpting was first introduced as a way to efficiently suppress solvent signals. It requires a pulse sequence that acts as a null pulse at the solvent-resonance frequency and as an inversion pulse everywhere else. In this article, it is shown that such a goal can be achieved starting with "top-hat" inversion shaped pulses such as I-BURP-2 or gaussian cascade G3. The result is a Globally Antisymmetric Selective Pulse, or GASP. Numerical optimization was used to extend the performance of such pulses. Multifrequency signal suppression was shown to be possible through application of successive excitation sculpting modules.
authors.affiliation: Pharmacognosy Laboratory, UMR-A 6013 CNRS, CPCBAI, Bat. 18, BP 1039, Moulin de la Housse, Reims, France. elise.prost@univ-reims.fr
authors.forename: Elise
authors.initials: E
authors.lastname: Prost
authors.forename: Philippe
authors.initials: P
authors.lastname: Sizun
authors.forename: Martial
authors.initials: M
authors.lastname: Piotto
authors.forename: Jean Marc
authors.initials: JM
authors.lastname: Nuzillard
mesh_terms: D002845:Chromatography; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009716:Numerical Analysis, Computer-Assisted; D012997:Solvents
chemical_list: D012997:Solvents