Solid-phase extraction and reversed-phase high-performance liquid chromatography of the five major alkaloids in Narcissus confusus.
A novel, fast and precise method, combining solid-phase extraction and reversed-phase high-performance liquid chromatography is described for the quantitative determination of five alkaloids (galanthamine, N-formylnorgalanthamine, haemanthamine, homolycorine and tazettine/pretazettine) from bulbs of wild Narcissus confusus, a high galanthamine-containing plant species growing in the Iberian Peninsula.
López
Susana
S
Department of Natural Products, Plant Biology and Edaphology, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Catalonia, Spain.
Bastida
Jaume
J
Viladomat
Francesc
F
Codina
Carles
C
D000470:Alkaloids / Q000737:chemistry*; D047151:Amaryllidaceae Alkaloids; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005702:Galantamine / Q000031:analogs & derivatives / Q000737:chemistry*; D015394:Molecular Structure; D031427:Narcissus / Q000737:chemistry*; D010617:Phenanthridines; D010936:Plant Extracts / Q000737:chemistry; D012044:Regression Analysis; D013057:Spectrum Analysis / Q000379:methods
D000470:Alkaloids; D047151:Amaryllidaceae Alkaloids; C473199:N-formylnorgalanthamine; D010617:Phenanthridines; D010936:Plant Extracts; D005702:Galantamine; C010766:pretazettine; C462104:hemanthamine; C057585:homolycorine; C011361:tazettine