title: [Antegrade selective cerebral perfusion for extended total arch replacement using separated graft technique; reassessment from the type of aneurysms and dissections].
abstract: One hundred eighty two patients with thoracic aortic aneurysms or dissections who required total arch replacement (TAR) were operated on with separated graft technique and selective cerebral perfusion (SCP) between 1991 and 2000. These patients were divided into 4 groups according to the pathology as follows: group 1; acute type A dissection, group 2; chronic type A dissection, group 3; distal arch aneurysm and group 4; proximal arch aneurysm. For SCP, both the innominate artery and the left common carotid artery were cannulated when the patient was cooled to a rectal temperature of 22 degrees C. Hospital mortalities were 27% in group 1, 14% in group 2, 19% in group 3, and 8% in group 4. Independent predictors of hospital mortality were shock, visceral, and leg ischemia in group 1, and circulatory arrest time of the lower half body to be more than 1 hour and cardiopulmonary bypass time to be more than 5 hours in group 3. Permanent neurological complication occurred in 3% in group 1 and 8% in group 3. Hospital mortality was affected by the type of aneurysms and dissections. It is necessary to give careful consideration to the indication of TAR with SCP, especially in acute type A dissection and distal arch aneurysm.
authors.affiliation: Department of Cardiothoracic Surgery, Sapporo Medical University, Sapporo, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Fukada
authors.forename: K
authors.initials: K
authors.lastname: Morishita
authors.forename: N
authors.initials: N
authors.lastname: Kawaharada
authors.forename: S
authors.initials: S
authors.lastname: Muraki
authors.forename: T
authors.initials: T
authors.lastname: Satsu
authors.forename: Y
authors.initials: Y
authors.lastname: Kurimoto
authors.forename: T
authors.initials: T
authors.lastname: Abe
mesh_terms: D000368:Aged; D000784:Aortic Dissection / Q000401:mortality / Q000601:surgery*; D001013:Aorta, Thoracic / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000145:classification* / Q000401:mortality / Q000601:surgery; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D002545:Brain Ischemia / Q000517:prevention & control; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010477:Perfusion / Q000379:methods*; D015996:Survival Rate