[The world of stem cells].
Since its beginning, at the turn of the 19th century, biology has been mostly--if not exclusively--analytical. Reductionism has progressively unveiled a series of structures buried into one another like Russian dolls. The study of the genome, the deepest structure of organisms, represents the triumph of reductionism. With the deciphering of the genome and the birth of what is called the 'proteome'--i.e. the study of the proteins and of their interactions--, a new stage appears. To the disorganisation that characterised two centuries of biology, a phase of reconstruction of living organisms is substituted. This is concerned first with interactions of proteins and of cells. In addition, one of the most remarkable tools for this latter research has been provided by embryonic stem cells.
Jacob
François
F
Institut Pasteur, 25, rue du Docteur-Roux, 75724 Paris, France. fjacob@pasteur.fr
D032984:Ethics, Research; D015894:Genome, Human; D006801:Humans; D012106:Research / Q000639:trends; D033581:Stem Cell Transplantation / Q000941:ethics*; D013234:Stem Cells