Ovine herpesvirus 2 lytic cycle replication and capsid production.
Ovine herpesvirus 2 (OvHV-2) causes malignant catarrhal fever in cattle, pigs and deer. We have observed intact circular and linear OvHV-2 genomes in infected T cell lines derived from cows and rabbits. Bovine T cell lines were predominantly latently infected but rabbit T cell lines supported OvHV-2 productive cycle gene expression and virus capsids were demonstrated for the first time.
Rosbottom
Jane
J
Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Summerhall, Edinburgh, UK1.
Dalziel
Robert G
RG
Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Summerhall, Edinburgh, UK1.
Reid
Hugh W
HW
Moredun Research Institute, Pentlands Science Park, Penicuik, UK2.
Stewart
James P
JP
Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Summerhall, Edinburgh, UK1.
D000818:Animals; D002213:Capsid / Q000378:metabolism*; D002417:Cattle; D002460:Cell Line; D004270:DNA, Circular / Q000032:analysis; D004279:DNA, Viral / Q000032:analysis; D018142:Gammaherpesvirinae / Q000235:genetics* / Q000378:metabolism / Q000502:physiology*; D006566:Herpesviridae Infections; D011817:Rabbits; D012756:Sheep / Q000821:virology*; D013601:T-Lymphocytes / Q000821:virology*; D014779:Virus Replication
D004270:DNA, Circular; D004279:DNA, Viral