The COS-7 cell in vitro paradigm to study myelin proteolipid protein 1 gene mutations.
Gow
Alexander
A
Center for Molecular Medicine and Genetics, Departments of Pediatrics and Neurology, Wayne State University School of Medicine, Detroit, MI, USA.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D019556:COS Cells; D002522:Chlorocebus aethiops; D002874:Chromosome Mapping; D003001:Cloning, Molecular / Q000379:methods; D017931:DNA Primers; D004195:Disease Models, Animal; D004587:Electrophoresis, Agar Gel / Q000379:methods; D005091:Exons; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007202:Indicators and Reagents; D008565:Membrane Proteins; D008954:Models, Biological; D008969:Molecular Sequence Data; D009154:Mutation; D020125:Mutation, Missense; D018991:Myelin Proteolipid Protein / Q000737:chemistry / Q000235:genetics*; D020371:Pelizaeus-Merzbacher Disease / Q000235:genetics*; D010957:Plasmids; D014176:Protein Biosynthesis; D014162:Transfection; D014960:X Chromosome
D017931:DNA Primers; D007202:Indicators and Reagents; D008565:Membrane Proteins; D018991:Myelin Proteolipid Protein; C472930:PLP1 protein, human