[The role of radiotherapy in the treatment of bone neoplasms].
Primary malignant bone neoplasms are relatively rare. The most common bone tumors are osteosarcoma,Ewing's sarcoma,chondrosarcoma, fibrosarcoma,malignant fibrous histiocytoma of bone, giant cell tumor, aneurysmal bone cyst and chordoma. These tumors are generally considered to be a radioresistant entities, but it has been suggested that radiotherapy may be effective in a palliative and in some curative situations, if a sufficient dose is given to an adequate volume. Only for the management of primary Ewing's sarcoma the radiation therapy is an essential part in the multimodal therapy concept. The most common bone neoplasms and the role of the radiotherapy are discussed in these chapter.
Koswig
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Strahlentherapie, Helios-Klinikum Berlin,Robert-Rössle-Klinik, Charité,Campus Buch, Berlin. skoswig@berlin.helios-kliniken.de
Budach
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V
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017824:Bone Cysts, Aneurysmal / Q000532:radiotherapy / Q000601:surgery; D001859:Bone Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D002813:Chondrosarcoma / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D002817:Chordoma / Q000532:radiotherapy / Q000601:surgery; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D005260:Female; D005354:Fibrosarcoma / Q000532:radiotherapy / Q000601:surgery; D005500:Follow-Up Studies; D005870:Giant Cell Tumors / Q000532:radiotherapy / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D012516:Osteosarcoma / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D010166:Palliative Care; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D012307:Risk Factors; D012512:Sarcoma, Ewing / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D013997:Time Factors