title: Primary CD56+ T/NK cell lymphoma of the colon.
abstract: Primary T/natural killer (NK) cell lymphoma of the colon is extremely rare. Despite the advances in histological and immunophenotypic studies, the diagnosis of primary T/NK cell lymphoma of the colon can be delayed because the early symptoms and colonoscopic findings may be very similar to those of inflammatory bowel diseases such an Crohn's colitis, and most physicians have little available information on this group of neoplasms. Moreover, florid nonspecific inflammatory infiltrates would not allow characterization of the tumor cells in such an inflammatory background. Herein, we describe a patient who initially presented with features that were clinically and colonoscopically similar to Crohn's colitis. Three months later, he had cecal bleeding and perforation, and primary T/NK cell lymphoma of the colon was diagnosed through immunophenotypic and genotypic studies of surgical specimens.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, 162 Ilsan-Dong, Wonju 220-701, Republic of Korea.
authors.forename: Hyun Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: Dong Ki
authors.initials: DK
authors.lastname: Lee
authors.forename: Soon Koo
authors.initials: SK
authors.lastname: Baik
authors.forename: Sang Ok
authors.initials: SO
authors.lastname: Kwon
authors.forename: Mee Yon
authors.initials: MY
authors.lastname: Cho
authors.forename: Young Hye
authors.initials: YH
authors.lastname: Ko
mesh_terms: D000328:Adult; D019002:CD56 Antigen / Q000032:analysis*; D003092:Colitis / Q000097:blood / Q000235:genetics* / Q000473:pathology*; D003110:Colonic Neoplasms / Q000097:blood / Q000235:genetics* / Q000473:pathology*; D003113:Colonoscopy; D003424:Crohn Disease / Q000097:blood / Q000235:genetics* / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000097:blood / Q000235:genetics* / Q000473:pathology*; D008297:Male
chemical_list: D019002:CD56 Antigen