title: [Multi-value regulatory systems for extracorporeal circulation].
abstract: Extracorporeal perfusion is the standard technique in cardiac surgery. It is controlled by perfusionists on the basis of their clinical experience and on the available data collected pre- and intra-operatively. But in spite of intensive monitoring postoperative complications occur. An appropriate control of the heart-lung machine (HLM) using an "autopilot" might improve the quality of heart-surgery and decrease postoperative complications. Hence, a mathematical model of a human circulatory system has been developed which provides much more information about haemodynamics, blood gases and acid-base status than standard monitoring. It has been implemented on a system which is capable of integrating measured data as input parameters in real-time in the simulation. Now, soft- and hardware control concepts based on the human circulatory system have to be developed which are able to control the HLM.
authors.affiliation: Institut für Industrielle Informationstechnik, Universität Karlsruhe (TH), Deutschland. Meyrowitz@iiit.etec.uni-karlsruhe.de
authors.forename: G
authors.initials: G
authors.lastname: Meyrowitz
authors.forename: T
authors.initials: T
authors.lastname: Schmidt
authors.forename: E
authors.initials: E
authors.lastname: Naujokat
authors.forename: J
authors.initials: J
authors.lastname: Albers
authors.forename: U
authors.initials: U
authors.lastname: Kiencke
authors.forename: C F
authors.initials: CF
authors.lastname: Vahl
authors.forename: S
authors.initials: S
authors.lastname: Hagl
mesh_terms: D003327:Coronary Disease / Q000601:surgery*; D017143:Fuzzy Logic; D006349:Heart Valve Diseases / Q000601:surgery*; D006355:Heart-Lung Machine; D006801:Humans; D008432:Mathematical Computing; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D011183:Postoperative Complications / Q000175:diagnosis / Q000628:therapy*