title: Carbonate ion-selective electrode with reduced interference from salicylate.
abstract: A carbonate ion-selective electrode for determination of total carbon dioxide species such as carbon dioxide, bicarbonate and carbonate with reduced interference from salicylate is described. Derivatives of trifluoroacetophenone were used as neutral carriers for carbonate. A polymer-free liquid carbonate-selective membrane with a cellophane outer membrane was found to give a carbonate-selective electrode with a negligible response to salicylate. The electrical contact was obtained by insertion of a silver/silver chloride electrode directly into the liquid membrane. The electrode does not require any aqueous filling solution and is therefore maintenance-free. The response to carbon dioxide species was found to be highly reproducible with a response time of 1-2 min at total carbon dioxide concentrations in the range from 5 to 50 mM. The lifetime of the electrode was at least 3 months. The electrode is regarded as very promising for clinical analysis of carbon dioxide species in body fluids such as plasma and serum.
authors.affiliation: Center for Process Analytical Chemistry and Sensor Technology (ProSens), Process Chemistry Group, Abo Akademi University, 20500 Abo, Finland.
authors.forename: Johan
authors.initials: J
authors.lastname: Bobacka
authors.forename: Magdalena
authors.initials: M
authors.lastname: Maj-Zurawska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Lewenstam
mesh_terms: D016477:Artifacts; D002245:Carbon Dioxide / Q000032:analysis* / Q000097:blood; D002254:Carbonates / Q000032:analysis* / Q000737:chemistry; D002476:Cellophane; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods; D004566:Electrodes; D008055:Lipids / Q000737:chemistry*; D008567:Membranes, Artificial; D011786:Quality Control; D015203:Reproducibility of Results; D012459:Salicylates / Q000032:analysis / Q000737:chemistry; D012680:Sensitivity and Specificity
chemical_list: D002254:Carbonates; D008055:Lipids; D008567:Membranes, Artificial; D012459:Salicylates; D002245:Carbon Dioxide; D002476:Cellophane