[Preliminary investigation of relationship between sperm apoptosis and male infertility].
OBJECTIVE
To evaluate the relationship between sperm apoptosis and male infertility.


METHODS
Percentage of apoptotic sperm (PAS) in spermatozoa of fertile and infertile men were tested by flow cytometry (FCM).


RESULTS
Sperm apoptosis had happened in all different people. PAS in fertile and infertile group was (4.28 +/- 1.66)% and (18.67 +/- 8.55)% respectively, and difference was significant between two groups (P < 0.01). There was negative correlation between PAS and semen volume, sperm density, percentage of forward motility, percentage of normal morphology (P < 0.01).


CONCLUSIONS
There was very close relationship between sperm apoptosis and male infertility. FCM used to test sperm apoptosis is rapid, accurate, objective and reliable to analyse sperm functions and male fertility.
Wang
Guang-Rong
GR
Family Planning Research Institute of Yunnan, Kunming, Yunan 650021, China.
Zhou
Zeng-Di
ZD
Ge
Zheng-Min
ZM
Zhao
Ming-Jun
MJ
D017209:Apoptosis; D005434:Flow Cytometry; D006801:Humans; D007248:Infertility, Male / Q000473:pathology*; D008297:Male; D013094:Spermatozoa / Q000473:pathology*