Cystic Fibrosis and Burkholderia pseudomallei Infection: An Emerging Problem?
We recently managed 4 patients with cystic fibrosis who had acquired Burkholderia pseudomallei infection after exposure in a region of endemicity. Person-to-person transmission between 2 siblings may have occurred; otherwise, the evidence suggests that cystic fibrosis may increase the likelihood of infection with this organism, and patients should be warned of this possibility and cautioned to avoid high-risk activities.
Holland
David James
DJ
LabPlus, Auckland Healthcare, Auckland, New Zealand. dholland@adhb.govt.nz
Wesley
Alison
A
Drinkovic
Dragana
D
Currie
Bart J
BJ
D000328:Adult; D016957:Burkholderia pseudomallei; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications* / Q000382:microbiology; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000453:epidemiology / Q000209:etiology* / Q000635:transmission