title: Septic arthritis due to Actinomyces naeslundii: report of a case.
abstract: In a man with osteoarthritis of the knee, Actinomyces naeslundii septic arthritis developed after intra-articular injection of hyaluronate. Actinomyces is an anaerobic Gram-positive rod. The outcome was favorable after treatment with two antibiotics and arthroscopy. The nature of the organism and its location to a joint are unusual features of this case, which illustrates the need to search for a septic complication before accepting a diagnosis of inflammation related to hyaluronate injection.
authors.affiliation: Rheumatology Department, Rouen University Hospital Charles-Nicolle, Unit INSERM 519, IFR 23, 76000 Rouen cedex 76031, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Lequerré
authors.forename: Michèle
authors.initials: M
authors.lastname: Nouvellon
authors.forename: Kataryna
authors.initials: K
authors.lastname: Kraznowska
authors.forename: Marie-Claire
authors.initials: MC
authors.lastname: Bruno
authors.forename: Olivier
authors.initials: O
authors.lastname: Vittecoq
authors.forename: Othmane
authors.initials: O
authors.lastname: Mejjad
authors.forename: Alain
authors.initials: A
authors.lastname: Daragon
authors.forename: Xavier
authors.initials: X
authors.lastname: Le Loët
mesh_terms: D000190:Actinomyces / Q000302:isolation & purification*; D000196:Actinomycosis / Q000150:complications / Q000473:pathology* / Q000628:therapy; D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000209:etiology / Q000473:pathology*; D004359:Drug Therapy, Combination; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D007270:Injections, Intra-Articular; D007719:Knee Joint / Q000382:microbiology / Q000473:pathology; D008297:Male; D020370:Osteoarthritis, Knee / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D012293:Rifampin / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000658:Amoxicillin; D006820:Hyaluronic Acid; D012293:Rifampin