title: [Gammadynamic treatment in advanced malignant tumors].
abstract: Since 1989 the total of 97 patients (173 tumours) have got gammadynamic treatment in Lithuanian oncology center. The treatment modality, when the sensitizer delivered to malignant tissue was activated by low dose (6-9 Gy) gammaradiation, which caused death of malignant tissues, was given the name of Gammadynamic treatment (GDT). Providing GDT Hematoporphyrin was injected i/v for patients and following 24, 48 and 72 hours after the injection tumours were irradiated with gamma rays 2-3 Gy at a time from the radioactive Co 60. As the immediate results of such treatment, 40 tumours completely disappeared; significant necrosis of 37 tumours and partial necrosis of 42 tumours was noticed.
authors.affiliation: Lietuvos onkologijos centras, Santariskiu 1, 2000 Vilnius. sekretoriatas@loc.lt
authors.forename: Laima
authors.initials: L
authors.lastname: Bloznelyte-Plesniene
authors.forename: Alfonsas
authors.initials: A
authors.lastname: Stancius
mesh_terms: D005500:Follow-Up Studies; D005720:Gamma Rays; D006415:Hematoporphyrins / Q000008:administration & dosage*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D010166:Palliative Care; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000008:administration & dosage*; D011838:Radiation-Sensitizing Agents / Q000008:administration & dosage*; D011879:Radiotherapy Dosage; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D006415:Hematoporphyrins; D017319:Photosensitizing Agents; D011838:Radiation-Sensitizing Agents