[Effects of Seroxat on premature ejaculation: a clinical trial].
OBJECTIVE
To evaluate the effects of antidepressant Seroxat on premature ejaculation.


METHODS
After having taken Seroxat 20 mg every noon for four weeks, the patients were asked to fill the investigating questionaire about the effects and side effects before and after the treatment.


RESULTS
After the treatment, 43 cases in our study had increased their ejaculation latency time, enhanced the quality of their sexy lives and their wives', and had significant difference compared with pre-treatment(P < 0.001). They had good effects on improving premature ejaculation after taking Seroxat (11.26 +/- 5.79) days; and after having stopped taking seroxat for (20.94 +/- 8.04) days, the situation of premature ejaculation in 32 cases were as same as that of before. There were seven cases whose sexuality and oomph increased, and two cases whose sexuality were decreased. A few patients had constipation, dry in mouth, insomnia and itch in skin, after taking the drugs.


CONCLUSIONS
Antidepressant Seroxat has rather good effects on premature ejaculation and should be used and studied further.
Qiu
Yong-Chao
YC
Department of Andrology and Urology, First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong 510405, China. yongchaoqiu@163.net
Wang
Xi-Kun
XK
Cui
Zhi-Bin
ZB
Lin
Shao-Hui
SH
Chen
Ming
M
D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004542:Ejaculation / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D017374:Paroxetine / Q000009:adverse effects / Q000627:therapeutic use*; D012735:Sexual Dysfunction, Physiological / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome
D000928:Antidepressive Agents; D017374:Paroxetine