title: [Values of white blood cell count in the diagnosis of acute appendicitis].
abstract: BACKGROUND
  The diagnosis of acute appendicitis remains a critical challenge for paediatric surgeons. White Blood Cell (WBC) count, once considered a basic exam, is still routinely performed in most institutions, despite its lack of accuracy. Aim of this study is to assess the additional value of WBC count in the diagnosis of acute appendicitis.
  
  
  METHODS
  We retrospectively reviewed the charts of children who underwent appendectomy for acute appendicitis in the last two years at our institution. In the patients treated in 1999 (Group A), WBC count was assessed routinely after admission. The surgeons relied on leukocytosis as well as on clinical findings and on ultrasound abdominal scan for the diagnosis of acute appendicitis. In the patients treated in 2000 (Group B), blood cell count was not tested or deliberately ignored by the surgeons.
  
  
  RESULTS
  There were 65 children in Group A and 70 in Group B; the two groups of patients were similar in terms of gender (p = 0.989) and age (p = 0.758). Criteria for operation were similar in the two groups (p = 0.222). No differences were found in the number of perforated (p = 0.989) and normal (p = 0.217) appendixes in the two groups as well as in the duration of hospital stay after surgery (p = 0.849).
  
  
  CONCLUSIONS
  WBC count at admission has no proven additional value in the diagnosis of acute appendicitis and can be omitted without modifying diagnostic pathway and without affecting diagnostic accuracy.
authors.affiliation: Divisione di Chirurgia Pediatrica, Università di Padova, Via Giustiniani, 3, 35126 Padova, Italia.
authors.forename: G
authors.initials: G
authors.lastname: Stefanutti
authors.forename: M
authors.initials: M
authors.lastname: Sabatti
authors.forename: D
authors.initials: D
authors.lastname: Gobbi
authors.forename: V
authors.initials: V
authors.lastname: Ghirardo
authors.forename: P G
authors.initials: PG
authors.lastname: Gamba
mesh_terms: D000208:Acute Disease; D000465:Algorithms; D001064:Appendicitis / Q000097:blood* / Q000175:diagnosis; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D012189:Retrospective Studies