title: [A clinical scoring system may identify good candidates for hepatic arterial infusion chemotherapy after hepatic resection for colorectal cancer].
abstract: The significance of hepatic arterial infusion chemotherapy (HAI) for the prognosis of metastatic colorectal cancer is controversial. We applied a clinical scoring system to find good candidates for HAI after hepatic resection. Ninety-four consecutive cases of hepatic metastases resected at a single institute were analyzed retrospectively. The cases were divided into 4 subgroups: those with a low risk score (0-2 points) with and without HAI and those with a high risk score (3-5 points) with and without HAI. The number of cases and the cumulative 5 year survival rate of each case were as follows: low risk score with HAI (n = 17) 64.1%, low risk score without HAI (n = 25) 27.4%, high risk score with HAI (n = 28) 16.9%, and high risk score without HAI (n = 24) 14.7%, respectively. These results suggest that hepatic resection with HAI seemed to contribute to the outcome for selected cases. The clinical scoring system may identify good candidates for HAI as well as predict recurrence after hepatic resection for metastatic colorectal cancer.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Bokuto Hospital.
authors.forename: Soichi
authors.initials: S
authors.lastname: Tanaka
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Umekita
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Maeshiro
authors.forename: Yukio
authors.initials: Y
authors.lastname: Miyamoto
authors.forename: Satoru
authors.initials: S
authors.lastname: Inoue
authors.forename: Satoru
authors.initials: S
authors.lastname: Matsuo
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Kitamura
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000473:pathology*; D006498:Hepatectomy; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy / Q000517:prevention & control* / Q000556:secondary* / Q000601:surgery; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D000970:Antineoplastic Agents