title: [Intrapleural streptokinase-streptodornase in the treatment of empyema and hemothorax].
abstract: Fourteen of 15 patients (93%) with retained pleural collections underwent successful enzymatic debridement and tube drainage with streptokinase-streptodornase (SK-SD) injections. No significant adverse reactions occurred. One patient required decortication when SK-SD therapy failed. Intrapleural SK-SD is a safe, effective means of removing retained proteinaceous collections in the pleural space. It may obviate the need for more invasive procedures.
authors.affiliation: Department of Surgery, National Kinki-chuou Hospital, Sakai, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Fujiwara
authors.forename: T
authors.initials: T
authors.lastname: Yasumitsu
authors.forename: K
authors.initials: K
authors.lastname: Nakagawa
authors.forename: S
authors.initials: S
authors.lastname: Shiono
authors.forename: K
authors.initials: K
authors.lastname: Fukuhara
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003646:Debridement; D003850:Deoxyribonuclease I / Q000627:therapeutic use*; D004322:Drainage / Q000379:methods*; D016724:Empyema, Pleural / Q000601:surgery*; D005260:Female; D006491:Hemothorax / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D035422:Pleural Cavity; D013300:Streptokinase / Q000627:therapeutic use*
chemical_list: D003850:Deoxyribonuclease I; D013300:Streptokinase