title: [The background of acid-base interactions in nonaqueous solvents--an analytical approach].
abstract: The acid-base determination of different substances by non-aqueous titrations is highly preferred in pharmaceutical analyses since the method is quantitative, exact and well reproducible. The modern interpretation of the reactions in nonaqueous solvents started in the past century, but several inconsistencies and unsolved problems can still be found in the literature. The acid-base theories of Brönsted-Lowry and Lewis as well as the so-called solvent theory are outlined first, then the promoting (and levelling) and the differentiating effects are discussed on the basis of the hydrogen bond concept.
authors.affiliation: ELTE Szervetlen és Analitikai Tanszék, Budapest, Pázmány Péter sétány 1/A-H-1117.
authors.forename: Lajos
authors.initials: L
authors.lastname: Barcza
authors.forename: Buvári Agnes
authors.initials: BA
authors.lastname: Barczáné
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology*; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D012997:Solvents
chemical_list: D012997:Solvents