Papillary pneumocytoma of the lung simulating a pleomorphic adenoma.
A rare case of papillary pneumocytoma of the lung is reported. The immunohistochemical positivities for EMA, cytokeratin and TTF-l strongly support the hypothesis that the neoplastic cells are originated from type 2 pneumocytes. The tumour also presented areas displaying stroma of non-specific mixoid appearance, simulating a benign tumour of the salivary gland type. We propose that these mixoid areas constitute structures of metaplastic origin.
Baldi
Alfonso
A
Department of Biochemistry and Biophysic F. Cedrangolo, Section of Anatomic Pathology, Second University of Naples, Naples, Italy.
Santini
Mario
M
Vicidomini
Giovanni
G
Ambrosino
Francesco
F
Vincenzi
Bruno
B
Costanzo
Rosaria
R
Di Leo
Carmen
C
Esposito
Vincenzo
V
Groeger
Angela M
AM
Baldi
Feliciano
F
D000236:Adenoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001984:Bronchial Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D018396:Mucin-1 / Q000032:analysis; D009687:Nuclear Proteins / Q000032:analysis; D013902:Radiography, Thoracic; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors / Q000032:analysis; D016896:Treatment Outcome
D014408:Biomarkers, Tumor; D018396:Mucin-1; D009687:Nuclear Proteins; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors; D007633:Keratins