Internalization of cellular fragments in a human embryo: time-lapse recordings.
An observation is reported of internalization of a cellular fragment into a blastomere from a human embryo, as documented by time-lapse photography. The fragment, created during the first mitotic cleavage was reabsorbed into one of the mother blastomeres in less than 5 min. The time-lapse sequence, shown here as a series of still photographs, provides the first direct evidence that cellular fragments in human embryos can 'disappear' during the culture period, a phenomenon that is common in human IVF. The time-lapse sequence itself may be viewed on the internet at www.rbmonline.com/Article/633.
Hardarson
T
T
Department of Obstetrics and Gynaecology, Göteborg University, SU/Sahlgrenska, 413 45 Gothenburg, Sweden. thorir.hardarson@obgyn.gu.se
Löfman
C
C
Coull
G
G
Sjögren
A
A
Hamberger
L
L
Edwards
R G
RG
D001757:Blastomeres / Q000166:cytology* / Q000502:physiology*; D046508:Culture Techniques; D004705:Endocytosis; D004867:Equipment Design; D006801:Humans; D008938:Mitosis / Q000502:physiology; D010781:Photography / Q000295:instrumentation / Q000379:methods