title: Purpura fulminans and anticardiolipin antibodies in a patient with Grave's disease.
abstract: We describe a patient with Grave's discase who developed purpura fulminans and who was found to have anticardiolipin antibodies after being started on propylthiouracil (PTU). We discuss the potential role of the antiphospholipid antibody in this woman's presentation, and its association to both PTU and autoimmune thyroid disease.
authors.affiliation: Division de Rhumatologie, Hôpital Maisonneuve-Rosemont, Université de Montreal, Canada.
authors.forename: Sophie
authors.initials: S
authors.lastname: Ligier
authors.forename: Cuong D
authors.initials: CD
authors.lastname: Pham
authors.forename: A Kevin
authors.initials: AK
authors.lastname: Watters
authors.forename: Jeannine
authors.initials: J
authors.lastname: Kassis
authors.forename: Paul R
authors.initials: PR
authors.lastname: Fortin
mesh_terms: D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000032:analysis / Q000276:immunology*; D013956:Antithyroid Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006111:Graves Disease / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D006801:Humans; D011695:IgA Vasculitis / Q000139:chemically induced* / Q000473:pathology; D011441:Propylthiouracil / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D017153:Antibodies, Anticardiolipin; D013956:Antithyroid Agents; D011441:Propylthiouracil