title: The core structure of TMC-95A is a promising lead for reversible proteasome inhibition.
authors.affiliation: AG Biorganische Chemie, Max-Planck Institut für Biochemie, Am Klopferspitz 18 A, 82152 Martinsried, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Kaiser
authors.forename: Michael
authors.initials: M
authors.lastname: Groll
authors.forename: Christian
authors.initials: C
authors.lastname: Renner
authors.forename: Robert
authors.initials: R
authors.lastname: Huber
authors.forename: Luis
authors.initials: L
authors.lastname: Moroder
mesh_terms: D003546:Cysteine Endopeptidases; D010450:Endopeptidases; D020128:Inhibitory Concentration 50; D008968:Molecular Conformation; D009097:Multienzyme Complexes / Q000037:antagonists & inhibitors*; D010456:Peptides, Cyclic / Q000737:chemistry* / Q000494:pharmacology; D011480:Protease Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D046988:Proteasome Endopeptidase Complex; D015003:Yeasts / Q000201:enzymology
chemical_list: D009097:Multienzyme Complexes; D010456:Peptides, Cyclic; D011480:Protease Inhibitors; C408291:TMC-95A; D010450:Endopeptidases; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex