title: A simple method for generating a blood pressure-unit activity relationship for central cardiovascular neurons in the rat.
abstract: One way to identify central cardiovascular neurons is to consider their barosensitivity, for example by plotting changes in their single unit activity as a function of evoked changes in blood pressure. To simplify the genesis of such pressure-activity relationships, a coronary angioplasty catheter was threaded into the aorta of anaesthetized rats and the balloon inflated to raise the blood pressure mechanically. Here, such a procedure is exemplified for cardiac vagal motoneurons in the medulla oblongata in eight rats. This simplification bypasses potentially problematic surgery and minimizes deterioration of the animal.
authors.affiliation: Physiology, School of Medicine, Lyon, France.
authors.forename: A
authors.initials: A
authors.lastname: Cividjian
authors.forename: N
authors.initials: N
authors.lastname: Rentero
authors.forename: R
authors.initials: R
authors.lastname: McAllen
authors.forename: L
authors.initials: L
authors.lastname: Quintin
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D002404:Catheterization / Q000295:instrumentation / Q000379:methods*; D004594:Electrophysiology; D008297:Male; D008526:Medulla Oblongata / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology; D011311:Pressoreceptors / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D014630:Vagus Nerve / Q000166:cytology / Q000502:physiology