title: Magnetization structure contrast based on intermolecular multiple-quantum coherences.
abstract: In vivo and ex vivo MRI based on intermolecular multiple-quantum coherences (iMQC) is predicted to provide a fundamentally different source of contrast for MRI. This article investigates the dependence of image contrast upon the choice of correlation distance for a heterogeneous material. A closely packed array of parallel hollow cylinders was used to demonstrate signal intensity variations when the correlation distance becomes comparable to the gap size between the cylinders. The observed effects agree well with three-dimensional calculations of the time evolution of magnetization under the nonlinear Bloch equations.
authors.affiliation: Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.
authors.forename: Louis-Serge
authors.initials: LS
authors.lastname: Bouchard
authors.forename: Rahim R
authors.initials: RR
authors.lastname: Rizi
authors.forename: Warren S
authors.initials: WS
authors.lastname: Warren
mesh_terms: D003287:Contrast Media; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008280:Magnetics; D008962:Models, Theoretical; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted
chemical_list: D003287:Contrast Media