Reference values for 99mTc-MAG3 renography determined in healthy, potential renal donors.
BACKGROUND
Reference values for 99mTc-MAG3 renography were determined and the influence of sex and age (< 50/ > or = 50 years) was elucidated.


METHODS
Sixty-eight potential renal donors were evaluated by renography among other tests. Through examination of their records 41 healthy subjects with a normal renal arteriography were included in this study and the reference values of the functional distribution (the split function, SF), the time to peak renal parenchymal activity (Tmax) and the residual activity (RA) were calculated.


RESULTS
For Tmax there was no significant influence of sex or age. Mean RA increased significantly with age (20.5 vs. 23.2%, P = 0.03), but no difference was found between sexes. Mean SF (right kidney) was significantly higher among males.


CONCLUSIONS
When a diuresis of at least 2 ml min-1 is demanded we found the following normal ranges: SF > 41%, Tmax < 4.3 min and RA < 33.7%.
Clausen
Thomas D
TD
Department of Clinical Physiology and Nuclear Medicine, Herlev Hospital, University of Copenhagen, Herlev Ringvej, Herlev, Denmark. tdclausen@mail.dk
Kanstrup
Inge-Lis
IL
Iversen
Jens
J
D000328:Adult; D000367:Age Factors; D000368:Aged; D004231:Diuresis; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011866:Radioisotope Renography / Q000592:standards*; D019275:Radiopharmaceuticals; D012016:Reference Values; D017263:Technetium Tc 99m Mertiatide; D014019:Tissue Donors
D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide