Pharmacology of synaptic transmission in the enteric nervous system.
Recent data indicate that there are multiple mechanisms mediating fast and slow synaptic excitation in the enteric nervous system. However, these data also suggest that both the neurotransmitters and the receptors mediating fast and slow synaptic transmission in the myenteric plexus are organized in a polarity- (ascending versus descending) and pathway- (excitatory versus inhibitory) specific manner.
Galligan
James J
JJ
Department of Pharmacology and Toxicology Life Science B440, Michigan State University, 48824, East Lansing, MI 48824, USA. galliga1@pilot.msu.edu
D000818:Animals; D004064:Digestive System / Q000187:drug effects* / Q000294:innervation*; D005765:Gastrointestinal Agents / Q000494:pharmacology*; D006801:Humans; D018377:Neurotransmitter Agents / Q000378:metabolism; D017981:Receptors, Neurotransmitter / Q000378:metabolism; D013569:Synapses / Q000187:drug effects* / Q000378:metabolism; D009435:Synaptic Transmission / Q000187:drug effects*
D005765:Gastrointestinal Agents; D018377:Neurotransmitter Agents; D017981:Receptors, Neurotransmitter