Jaw development: chinless wonders.
It has been suggested that the regionally restricted expression of Dlx genes acts to pattern the proximodistal axis of the pharyngeal arches during vertebrate development. Recently, clear evidence of this has emerged from Dlx-5; Dlx-6 double mutants, in which the lower jaw is transformed to an upper jaw.
Graham
Anthony
A
MRC Center for Developmental Neurobiology, 4th Floor New Hunts House, Guys Campus, Kings College London, London SE1 1UL, UK.
D000818:Animals; D019521:Body Patterning / Q000502:physiology*; D002816:Chordata, Nonvertebrate; D007568:Jaw / Q000033:anatomy & histology*; D007798:Lampreys; D008322:Mammals; D010802:Phylogeny