title: [Sjögren's syndrome in the elderly].
abstract: Sjögren's syndrome is an immune exocrinopathy. This paper will deal with the primary Sjogren's syndrome non associated with another rheumatologic disease (polyarthritis or systemic lupus erythematosus). Its prevalence is claimed to increase with age. The main clinical manifestation is salivary and/or ocular dryness due to a lymphocytic infiltration of the salivary or lacrimal glands or both. However, sicca symptoms are very frequent in the elderly, most often iatrogenic. The problem, particularly in this population, is the diagnosis of Sjögren's syndrome. There are yet no consensual criteria, the most used in the literature are the European criteria, published in 1993 and revised in 1996. Some tests, such as the Schirmer's test and non stimulated salivary flow, are not specific over 60 years. The results of other tests are discussed as the focus score on the lip salivary glands biopsy. The diagnosis of Sjögren's syndrome should be envisaged in the elderly, when systemic manifestations are associated with sicca symptoms.
authors.affiliation: Service de Médecine Interne, CHU La Cavale Blanche, 29285 Brest. armelle.gentric@univ-brest.fr
authors.forename: Armelle
authors.initials: A
authors.lastname: Gentric-Tilly
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000032:analysis; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000032:analysis; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D014985:Xerophthalmia / Q000209:etiology; D014987:Xerostomia / Q000209:etiology
chemical_list: D001323:Autoantibodies; D012217:Rheumatoid Factor