title: Generation and use of an equivalent of difluoroacetamide or difluoroacetate anions.
abstract: Ethers of trifluoroacetaldehyde hemiaminals can undergo dehydrofluorination under basic conditions to provide ethers of difluoroketene hemiaminals. The latter behave as equivalents of difluoroacetamide or difluoroacetate anions towards various electrophiles, yielding a range of difluoromethylcarbonyl products.
authors.affiliation: Laboratoire SERCOF (UMR CNRS 5622) Université Claude Bernard-Lyon 1 Bât. Chevreul 43, Bd du 11 novembre 1918, 69622 Villeurbanne, France.
authors.forename: Gaëlle
authors.initials: G
authors.lastname: Blond
authors.forename: Thierry
authors.initials: T
authors.lastname: Billard
authors.forename: Bernard R
authors.initials: BR
authors.lastname: Langlois
mesh_terms: D000577:Amides / Q000138:chemical synthesis; D017611:Fluorine Compounds / Q000138:chemical synthesis / Q000737:chemistry; D005463:Fluoroacetates / Q000138:chemical synthesis*
chemical_list: D000577:Amides; D017611:Fluorine Compounds; D005463:Fluoroacetates; C027495:difluoroacetic acid