The assessment of IgG avidity in the evaluation of perinatal herpes simplex virus infection.
Classical serologic assays are not useful for the diagnosis of perinatal herpes simplex virus (HSV) infection during the acute phase of the disease. We report two cases of neonatal HSV infection that highlight the diagnostic value of HSV-specific IgG avidity and its contribution for further characterization of neonatal HSV infection.
Odièvre
Marie-Hélène
MH
Service de Pédiatrie et Réanimation Néonatales, Hôpital Antoine-Béclère, Assistance Publique/Hôpitaux de Paris, Clamart, France.
Cointe
Denis
D
Thébaud
Bernard
B
Zupan
Véronique
V
Ingrand
Didier
D
Lacaze-Masmonteil
Thierry
T
Grangeot-Keros
Liliane
L
D000915:Antibody Affinity / Q000502:physiology*; D005260:Female; D006561:Herpes Simplex / Q000097:blood* / Q000503:physiopathology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000502:physiology*; D007231:Infant, Newborn; D008297:Male; D018139:Simplexvirus / Q000302:isolation & purification / Q000502:physiology*
D007074:Immunoglobulin G