Diagnosis of coronary artery disease based on blood pool radioisotope angiography at rest.
BACKGROUND
The author wanted to determine which of 3 parameters (global left ventricular ejection, regional left ventricular ejection fraction, or isocontours together with peak filling rate and time of peak filling rate) measured with blood pool radioisotope angiography at rest was sufficient to permit diagnosis of coronary artery disease.


METHODS
Thirty-one patients with coronary artery disease and 11 hypertensive patients without coronary heart disease were assessed with blood pool radioisotope angiography using a computerized large-field gamma camera.


RESULTS
Of the 3 parameters measured, only assessment of isocontours with peak filling rate and time of peak filling rate provided sufficient information for establishing a diagnosis of coronary artery disease. In contrast, measurement of global left ventricular ejection provided equivocal data, as did that of regional left ventricular ejection fraction.


CONCLUSIONS
In combination with peak filling rate and time of peak filling rate, measurement of isocontours by blood pool radioisotope angiography at rest provided sufficient information for establishing a diagnosis of coronary artery disease.
Indovina
A
A
Department of Medicine, University of Palemo, Palermo, Italy. aindovin@mbox.unipa.it
D000328:Adult; D017023:Coronary Angiography / Q000379:methods*; D003327:Coronary Disease / Q000175:diagnosis*; D005260:Female; D015637:Gated Blood-Pool Imaging; D006801:Humans; D008297:Male; D008875:Middle Aged