Zn(II)-mediated alkynylation-cyclization of o-trifluoroacetyl anilines: one-pot synthesis of 4-trifluoromethyl-substituted quinoline derivatives.
A novel efficient route to 4-trifluoromethyl-substituted quinoline derivatives through the Zn(II)-mediated alkynylation-cyclization of o-trifluoroacetyl anilines is described.
Jiang
Biao
B
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, People's Republic of China. jiangb@pub.sioc.ac.cn
Si
Yu-Gui
YG