Sentinel lymph node evaluation for tumor metastasis.
The sentinel lymph node biopsy procedure for evaluation of metastatic tumor has become a common procedure for breast carcinoma and malignant melanoma. There is little standardization in the histopathologic management of these specimens. The history, technical details, and histopathologic work-up for sentinel lymph node biopsy are reviewed. Particular attention is paid to the intraoperative consultation and a protocol for optimal histopathologic management is presented.
Hunt
Jennifer L
JL
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. HUNTJL@msx.upmc.edu
Baloch
Zubair W
ZW
LiVolsi
Virginia A
VA
D006801:Humans; D007150:Immunohistochemistry; D007432:Intraoperative Period; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D010340:Pathology, Surgical / Q000379:methods*; D021701:Sentinel Lymph Node Biopsy; D013048:Specimen Handling