[Long-term results of selective vagotomy plus antrectomy in treatment of duodenal ulcer].
OBJECTIVE
To study the long-term results of selective vagotomy plus antrectomy in treatment of duodenal ulcer.


METHODS
One hundred and ninety-three patients with duodenal ulcer were subjected to selective vagotomy plus antrectomy from November 1977 to November 2001. These patients included 28 patients with refractory ulcer, 112 with recurrent bleeding, 41 with pylori obstruction, and 12 with duodenal and gastric ulcer.


RESULTS
BAO, IMAO, PMAO and serum gastrin were decreased significantly after an 1 - 24-year follow-up after selective vagotomy plus antrectomy. The characteristics of inhibitory secretive were observed in parietal cells. Follow-up after operation for 1 - 10 years and 11 - 24 years showed that 95.60% and 96.61% of patients belonged to Visick grade I and II, and 4.40% and 3.39% of patients belonged to Visick grade III, respectively. No ulcer recurrence was seen during the 1 - 24 year follow-up after the operation.


CONCLUSIONS
SV + A is an effective method for duodenal ulcer, especially for complicated duodenal ulcer, with permanent reduction of gastric acid and no recurrence.
Wu
Xingjiang
X
Department of General Surgery, General Hospital of Nanjing Unit, People's Liberation Army, Nanjing 210002, China.
Li
Ning
N
Han
Jianming
J
Liu
Fukun
F
Xu
Zhe
Z
Li
Jieshou
J
D000328:Adult; D013505:Digestive System Surgical Procedures; D004381:Duodenal Ulcer / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D011708:Pylorus; D016896:Treatment Outcome; D014629:Vagotomy, Proximal Gastric