A remarkably efficient synthesis of pure cis-stilbenoid hydrocarbons using trans-dibromoalkenes via palladium catalysis.
A remarkably versatile synthesis of cis-stilbenoid hydrocarbons containing highly functionalized phenyl groups is developed via an efficient palladium-catalyzed coupling of aryl Grignard reagents with trans-1,2-dibromoalkenes (generally obtained via bromination of the corresponding dialkylacetylenes) in tetrahydrofuran.
Rathore
Rajendra
R
Marquette University, Department of Chemistry, PO Box 1881, Milwaukee, WI 53201-1881, USA. rajendra.rathore@mu.edu
Deselnicu
Mihaela I
MI
Burns
Carrie L
CL
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D010165:Palladium / Q000737:chemistry; D013267:Stilbenes / Q000138:chemical synthesis* / Q000737:chemistry
D000475:Alkenes; D006842:Hydrocarbons, Brominated; D013267:Stilbenes; D010165:Palladium