title: [Sudden bilateral hearing loss disclosing meningeal carcinomatosis].
abstract: We report the case of a patient presenting a sudden bilateral hearing loss. Four years before, a bladder carcinoma was resected and a chemotherapy was started. Gadolinium-enhanced magnetic resonance images revealed enhancement of both acoustic nerves. Cerebrospinal fluid analysis showed malignant cells consistent with the initial bladder cancer. Meningeal metastases from bladder carcinoma are extremely rare. Systemic chemotherapy and its low meningeal diffusion may enhance the incidence of this complication. Bilateral hearing loss is a rare initial manifestation of meningeal carcinomatosis.
authors.affiliation: Service de neurologie, Hôpital Beaujon 92110 Clichy. yboukriche@invivo.edu
authors.forename: Y
authors.initials: Y
authors.lastname: Boukriche
authors.forename: D
authors.initials: D
authors.lastname: Bouccara
authors.forename: F
authors.initials: F
authors.lastname: Cyna-Gorse
authors.forename: C
authors.initials: C
authors.lastname: Dehais
authors.forename: M
authors.initials: M
authors.lastname: Felce-Dachez
authors.forename: C
authors.initials: C
authors.lastname: Masson
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002277:Carcinoma / Q000150:complications* / Q000175:diagnosis* / Q000556:secondary; D003056:Cochlear Nerve / Q000473:pathology; D006312:Hearing Loss, Bilateral / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000556:secondary; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents