Tandem reactions to construct heterocycles via phosphine-catalyzed umpolung addition and intramolecular conjugate addition.
[reaction: see text] A highly efficient method for constructing heterocycles was achieved by phosphine-catalyzed tandem umpolung addition and intramolecular conjugate addition. This strategy offers a simple and promising method for constructing synthetically useful heterocycles under neutral conditions with high atom economy.
Lu
Cheng
C
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai, 200032, China.
Lu
Xiyan
X