title: [Recurrence of right breast cancer at the thoracic wall successfully treated with intra-arterial infusion of doxorubicin hydrochloride--a case report].
abstract: We report a recurrent case of breast cancer successfully treated with intra-arterial infusion of doxorubicin hydrochloride (ADM) combined with systemic CAF therapy. The patient, a 37-year-old woman, was diagnosed with a recurrence at the thoracic wall 55 months after curative resection for right breast cancer. She was treated with intra-arterial infusion chemotherapy of ADM, 30 mg, combined with systemic CAF therapy of cyclophosphamide, 100 mg from days 1 to 14, ADM, 30 mg on days 1 and 8, and 5-fluorouracil, 500 mg on days 1 and 8, as one course. Two courses of the treatment resulted in a complete response of the tumor. This result suggests that local and systemic chemotherapy could be effective for the treatment of local recurrence of breast cancer.
authors.affiliation: Dept. of Surgery, Kowan Hospital.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Hasegawa
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Naoki
authors.initials: N
authors.lastname: Ishiwa
authors.forename: Takaki
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Soichirou
authors.initials: S
authors.lastname: Morinaga
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Noguchi
authors.forename: Akihiko
authors.initials: A
authors.lastname: Matsumoto
authors.forename: Junichi
authors.initials: J
authors.lastname: Nishimura
authors.forename: Takafumi
authors.initials: T
authors.lastname: Okoshi
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000601:surgery; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial; D007269:Injections, Intra-Arterial; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local; D013899:Thoracic Neoplasms / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents; D004317:Doxorubicin; D003520:Cyclophosphamide; D005472:Fluorouracil