Severe scleritis and urticarial lesions.
OBJECTIVE
To report the first known case of bilateral scleritis in a patient with hypocomplementemic urticarial vasculitis.


METHODS
Interventional case report.


METHODS
Medical and ophthalmic history, results of physical and ophthalmic examinations, laboratory data, and histologic and immunopathologic examination were reviewed and results recorded.


RESULTS
A 67-year-old man who presented with eye redness and pain, rash, arthralgia, and malaise was found to have hypocomplementemic urticarial vasculitis. Treatment with high-dose oral corticosteroids and mycophenolate mofetil resulted in the resolution of the rash and scleritis.


CONCLUSIONS
Ocular involvement may be a helpful clue in the diagnosis of this uncommon syndrome.
Thorne
Jennifer E
JE
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. jthorne@jhmi.edu
Hernandez
Maria I
MI
Rencic
Adrienne
A
Nousari
H Carlos
HC
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000097:blood; D003176:Complement C3 / Q000172:deficiency; D003181:Complement C4 / Q000172:deficiency; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D015423:Scleritis / Q000150:complications*; D014581:Urticaria / Q000150:complications*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000974:Antibodies, Antinuclear; D003176:Complement C3; D003181:Complement C4; D005938:Glucocorticoids; D009173:Mycophenolic Acid; D011241:Prednisone