title: The interdependence of nuclear structure and function.
abstract: 2001 was the year of the human genome, but the new information has had little immediate impact on the field of nuclear structure. Rather, functional studies - especially on transcription - are leading us to a better understanding of how genomes might organise themselves into structures we call nuclei.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford, South Parks Road, OX1 3RE, Oxford, UK.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Iborra
authors.forename: Peter R
authors.initials: PR
authors.lastname: Cook
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure*; D002843:Chromatin / Q000648:ultrastructure; D004260:DNA Repair; D004261:DNA Replication; D006801:Humans; D008957:Models, Genetic; D034443:RNA Transport; D011995:Recombination, Genetic; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin