title: Valorization of grape (Vitis vinifera) byproducts. Antioxidant and biological properties of polyphenolic fractions differing in procyanidin composition and flavonol content.
abstract: Many byproducts and wastes generated by agroindustries contain polyphenols with potential application as food antioxidants and preventive agents against skin cancer and other diseases. The performance of polyphenolic fractions from Parellada grape (Vitis vinifera) pomace as antioxidants in different physicochemical environments was tested. Fractions containing oligomers with mean degree of polymerization between 3 and 4 and percentage galloylation ca. 30% were the most potent free radical scavengers and efficient antioxidants in an oil-in-water emulsion. A fraction including glycosylated flavonols was also efficient in the emulsion. All the fractions showed low aquatic toxicity and weak influence on proliferation of human melanoma cells.
authors.affiliation: Department of Peptide and Protein Chemistry, Department of Surfactant Technology, and Thermal Analysis Laboratory, Institute for Chemical and Environmental Research (IIQAB-CSIC), Jordi Girona 18-26, 08034 Barcelona, Spain. jltqbp@iiqab.csic.es
authors.forename: Josep Lluís
authors.initials: JL
authors.lastname: Torres
authors.forename: Begoña
authors.initials: B
authors.lastname: Varela
authors.forename: María Teresa
authors.initials: MT
authors.lastname: García
authors.forename: Josep
authors.initials: J
authors.lastname: Carilla
authors.forename: Cecilia
authors.initials: C
authors.lastname: Matito
authors.forename: Josep J
authors.initials: JJ
authors.lastname: Centelles
authors.forename: Marta
authors.initials: M
authors.lastname: Cascante
authors.forename: Xavier
authors.initials: X
authors.lastname: Sort
authors.forename: Raül
authors.initials: R
authors.lastname: Bobet
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D044946:Biflavonoids; D002392:Catechin / Q000032:analysis*; D002455:Cell Division / Q000187:drug effects; D005591:Chemical Fractionation; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003543:Cysteamine / Q000737:chemistry; D004655:Emulsions; D005419:Flavonoids / Q000032:analysis*; D044948:Flavonols; D016166:Free Radical Scavengers / Q000494:pharmacology; D006031:Glycosylation; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008545:Melanoma / Q000473:pathology; D010636:Phenols / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D010938:Plant Oils / Q000737:chemistry; D011108:Polymers / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D044945:Proanthocyanidins; D014407:Tumor Cells, Cultured; D027843:Vitis / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D044946:Biflavonoids; D004655:Emulsions; D005419:Flavonoids; D044948:Flavonols; D016166:Free Radical Scavengers; D010636:Phenols; D010938:Plant Oils; D011108:Polymers; D044945:Proanthocyanidins; C017674:procyanidin; D003543:Cysteamine; D002392:Catechin