title: [The changes of IL-1 and NO levels in the testes of rats with experimental varicocele].
abstract: OBJECTIVE
  To evaluate the effects of varicocele (VC) on IL-1 and NO levels in testes of rats with VC.
  
  
  METHODS
  Male adult Wistar rats were divided into two groups randomly, VC group (n = 30) and pseudo-operation group (n = 20), and the levels of IL-1 and NO in the testes were determined and compared.
  
  
  RESULTS
  The levels of IL-1 and No of left tests in VC group were higher than those in pseudo-operation group, respectively(P < 0.01). While the levels of IL-1 and NO of right testes between two groups were not significantly different (P > 0.05). More over, the level of IL-1 correlated significantly with that of NO(r = 0.572, P < 0.01).
  
  
  CONCLUSIONS
  The results revealed that the changes of IL-1 and NO levels in the testes of rats with VC might be the reason which caused testes damage, disturbance of spermatogenesis and even infertility.
authors.affiliation: Department of Obstetric and Gynecology, Jiamusi Center Hospital, Jiamusi, Heilongjiang 154002, China.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Chen
authors.forename: Shu-Qiu
authors.initials: SQ
authors.lastname: Wang
authors.forename: Yu-Zhen
authors.initials: YZ
authors.lastname: Zhao
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Shu-Xiang
authors.initials: SX
authors.lastname: Wang
authors.forename: Ya-Zhen
authors.initials: YZ
authors.lastname: Lu
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D007375:Interleukin-1 / Q000378:metabolism*; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013737:Testis / Q000378:metabolism* / Q000648:ultrastructure; D014646:Varicocele / Q000378:metabolism*
chemical_list: D007375:Interleukin-1; D009569:Nitric Oxide