title: Long-term results of Heller myotomy without an antireflux procedure in achalasic patients.
abstract: Both open and laparoscopic myotomies have been used in the treatment of achalasia. Postoperative gastro-oesophageal reflux is among the commonly reported side effects of myotomy. The addition of an antireflux procedure to the standard surgical approach has given rise to controversy. The objective of our study was to determine whether or not an antireflux procedure should be used in addition to Heller myotomy. Over the period from 1980 to 1990, 94 patients (mean age: 47.9 years) with achalasia underwent Heller myotomy calibrated by intraoperative oesophageal manometry without fundoplication. In 1999-2000, all patients filled in a clinical questionnaire: all underwent radiographic oesophageal imaging, oesophageal manometry, ambulatory 24-h oesophageal pH monitoring, and oesophagogastroduodenoscopy, when necessary. Ten healthy age-matched subjects were compared in the manometric and radiological studies. Myotomy improved the clinical profiles and instrumental data results in all patients. Gastro-oesophageal reflux was present in 10 patients (10.6%); none of these 10 subjects presented oesophagitis. Heller open myotomy yields good long-term results. Intraoperative manometric calibration reduces the side effects of myotomy, such as gastro-oesophageal reflux. The addition of fundoplication is not justified in all patients.
authors.affiliation: Dipartimento di Area Critica Medico-Chirurgica Clinica Chirurgica Generale, Università degli Studi di Firenze.
authors.forename: Camillo
authors.initials: C
authors.lastname: Cortesini
authors.forename: Fabio
authors.initials: F
authors.lastname: Cianchi
authors.forename: Filippo
authors.initials: F
authors.lastname: Pucciani
mesh_terms: D000328:Adult; D000368:Aged; D002299:Cardia / Q000601:surgery*; D003627:Data Interpretation, Statistical; D004384:Duodenoscopy; D004931:Esophageal Achalasia / Q000601:surgery*; D004945:Esophagoscopy; D004947:Esophagus / Q000601:surgery*; D005500:Follow-Up Studies; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000517:prevention & control*; D005773:Gastroscopy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008365:Manometry; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D013997:Time Factors