title: [The occurrence of Echinococcus multilocularis in red foxes in lower Saxony: identification of a high risk area by spatial epidemiological cluster analysis].
abstract: There is considerable interest in the spatial distribution of Echinococcus multilocularis in red foxes (Vulpes vulpes L.), because this parasite causes the zoonoses of alveolar echinococcosis which is potentially of high fatality rate. High risk areas are known from France, Switzerland and the Swabian Alb in Germany for a long time. In this work, the spatial scan statistic is introduced as an instrument for identification and localisation of high risk areas, so called disease clusters in spatial epidemiology. The use of the spatial scan statistic along with data about the distribution of the parasite in 5365 red foxes in Lower Saxony, that were collected during 1991 to 1997, led to the identification of another high risk area. The relative risk for this disease cluster is approximated by RR = 5.03 (CI0.95(RR) = [4.27; 6.58]) for the period of 1991 to 1994 and by RR = 4.45 (CI0.95(RR) = [3.53; 5.59]) for the period of 1994 to 1997, respectively.
authors.affiliation: Institut für Biometrie, Epidemiologie und Informationsverarbeitung, Tierärztliche Hochschule Hannover. olaf.berke@tiho-hannover.de
authors.forename: Olaf
authors.initials: O
authors.lastname: Berke
authors.forename: Michael
authors.initials: M
authors.lastname: von Keyserlingk
authors.forename: Susanne
authors.initials: S
authors.lastname: Broll
authors.forename: Lothar
authors.initials: L
authors.lastname: Kreienbrock
mesh_terms: D000818:Animals; D016000:Cluster Analysis; D004443:Echinococcosis / Q000453:epidemiology / Q000662:veterinary*; D004446:Echinococcus / Q000302:isolation & purification; D005260:Female; D005589:Foxes / Q000469:parasitology*; D005843:Geography; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D011157:Population Dynamics; D015995:Prevalence; D012307:Risk Factors; D015047:Zoonoses