title: [Wide excision as a method of breast-conserving surgery for breast cancer].
abstract: Breast-conserving treatment has become the standard treatment for early breast cancer, not only in Western countries but also in Japan. Wide excision is perferred to quadrantectomy because the former results in better cosmesis than the latter. However, the margin status may be positive more frequently in the former than in the latter. The results of our study indicated that positive margins and the absence of radiotherapy or endocrine therapy proved to be independent risk factors for local recurrence. Because margin status influences local control, tumor margins after wide excision should be accurately determined, and higher doses of radiotherapy and adjuvant therapy are indicated for patients with positive margins.
authors.affiliation: Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Inaji
authors.forename: Tetsu
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Komoike
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Motomura
authors.forename: Hiroki
authors.initials: H
authors.lastname: Koyama
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D015412:Mastectomy, Segmental / Q000379:methods* / Q000401:mortality; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate