title: Hepatic encephalopathy in primary human immunodeficiency virus type 1 (HIV-1) infection.
abstract: Primary infection of human immunodeficiency virus type 1 (HIV-1) is occasionally associated with common cold-like symptoms, and rarely with a self-limited illness resembling infectious mononucleosis. We report a 32-year-old man who presented with infectious mononucleosis-like blood picture on admission. Five days after admission he developed hepatic encephalopathy, which was ameliorated by administration of bolus corticosteroid. Based on the results of serologic studies, we diagnosed that he had primary HIV-1 infection. To our knowledge, this is the first published report of hepatic encephalopathy as a clinical manifestation of primary HIV-1 infection.
authors.affiliation: Department of Hematology and Clinical Immunology, Kobe City General Hospital, Kobe.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kobessho
authors.forename: Akiko
authors.initials: A
authors.lastname: Matsushita
authors.forename: Ken
authors.initials: K
authors.lastname: Takahashi
authors.forename: Makiko
authors.initials: M
authors.lastname: Shimodaira
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishihara
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Oita
authors.forename: Takayuki
authors.initials: T
authors.lastname: Takahashi
mesh_terms: D000328:Adult; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006501:Hepatic Encephalopathy / Q000150:complications*; D006801:Humans; D008297:Male