[The establishment of testicular fibrosis model in Wistar rats].
OBJECTIVE
To establish the testicular fibrosis model in rats.


METHODS
Wistar rats were divided into control group(n = 12) and model group(n = 40) randomly. Testicular fibrosis model was built with the classical method of establishing experimental autoimmune orchitis (EAO) combined with injecting Bacille Calmette-Guerin (BCG) into left testis.


RESULTS
The incidence rate of EAO and the rate of testicular fibrosis were 100%, 11.1% and 100%, 81.5% at 80, 140 days after the first infection, respectively.


CONCLUSIONS
The model of rat testicular fibrosis was established successfully.
Wang
Tao
T
Department of Pathology, Hebei Medical University, Shijiazhuang, Hebei 050017, China.
Ma
Yu-Mei
YM
Xiu
He-Ming
HM
Zhao
Qu-Sheng
QS
Sun
Hui-Chen
HC
Xu
Zheng
Z
Ben
Chang-En
CE
D000818:Animals; D001327:Autoimmune Diseases / Q000473:pathology*; D004195:Disease Models, Animal; D005355:Fibrosis; D008297:Male; D009163:Mycobacterium bovis; D009920:Orchitis / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D013737:Testis / Q000473:pathology*