Using transcriptional-based systems for in vivo enzyme screening.
Firestine
Steven M
SM
Department of Medicinal Chemistry, Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA, USA.
Salinas
Frank
F
Benkovic
Stephen J
SJ
D003001:Cloning, Molecular; D020650:Combinatorial Chemistry Techniques; D004353:Drug Evaluation, Preclinical; D004798:Enzymes / Q000235:genetics* / Q000378:metabolism*; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005822:Genetic Vectors; D017434:Protein Structure, Tertiary; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D013379:Substrate Specificity; D014158:Transcription, Genetic; D020798:Two-Hybrid System Techniques
D004798:Enzymes; D011994:Recombinant Proteins