[Correlation between tissue ultrastructure changes of small testis and sex hormone].
OBJECTIVE
To investigate the tissue ultrastructure changes of small testis and sex hormone and their correlation.


METHODS
The patients were divided into small tests (n = 8) and control group(n = 12). FSH, LH, T were determined by radioimmunassay. Diameter and wall thickness of convoluted seminiferous tubule were investigated with light microscope and electro microscopy on small testis tissue morphology and ultrastructure.


RESULTS
FSH, LH, T of small testis and control group were (21.05 +/- 9.15) IU/L vs (6.74 +/- 3.52) IU/L, (22.88 +/- 6.25) IU/L vs (6.60 +/- 1.48) IU/L and (0.30 +/- 0.04) nmol/L vs (17.55 +/- 9.25) nmol/L, respectively. Seminiferous tubule diameter and wall thickness were(37.33 +/- 6.80) microns vs (198.46 +/- 29.84) microns and (10.30 +/- 1.82) microns vs (2.95 +/- 0.20) microns. Small testis tissue ultrastructure changed significantly.


CONCLUSIONS
Pathologic changes of small testis tissue in many parts such as seminiferous tubule, germinal epithelium, Sertoli cell, Leydig cell, limiting membrance and blood vessel may relate with genetics and immunoreaction.
Ke
Guo-An
GA
Department of Plastic Surgery, Fifth Hospital of Huangshi, Huangshi, Hubei 435005, China.
Long
Dao-Chou
DC
Shan
Sheng-Guo
SG
D000328:Adult; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism; D008297:Male; D013223:Statistics as Topic; D013737:Testis / Q000033:anatomy & histology / Q000378:metabolism / Q000648:ultrastructure*; D013739:Testosterone / Q000378:metabolism
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone