Primary non-Hodgkin's lymphoma in Bartholin's gland.
BACKGROUND
Non-Hodgkin's lymphoma (NHL) may involve the lower female genital tract, most often as a manifestation of systemic disease and rarely as a primarily localisation.


METHODS
A 73-year-old woman, HIV-negative, presented with a 5-month history of a mass in the left Bartholin's gland. The performed biopsy was reported to be a poorly differentiated carcinoma. Therefore, the patient underwent a vulvectomy with superficial groin node dissection. Unexpectedly, the definitive histological diagnosis showed that the tumor was an extranodal diffuse large B-cell non-Hodgkin lymphoma.


CONCLUSIONS
This is the first report of a NHL located in the Bartholin's gland. Primary NHLs involving the external genitalia are rare and often inaccurately diagnosed. A greater awareness of this entity among clinicians and pathologists could uncover more cases.
Tjalma
Wiebren A A
WA
Division of Gynaecological Oncology, University Hospital Antwerp, Wilrijkstraat 10, 2650, Antwerp, Belgium. wiebren.tjalma@uza.be
Van de Velde
Ann L R
AL
Schroyens
Wilfried A M
WA
D000368:Aged; D001472:Bartholin's Glands / Q000473:pathology*; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D014846:Vulvar Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy