title: Rocuronium-induced generalized spontaneous movements cause pulmonary aspiration.
abstract: Rapid-sequence induction with cricoid pressure is a standard procedure for inducing anesthesia in patients with a potentially full stomach. During the induction period, if the patient develops generalized movements of the body, the pressure level of the cricoid may change unexpectedly. As a result, the increase in intragastric pressure may cause gastric regurgitation and consequent pulmonary aspiration. Rocuronium has been widely used as an alternative to succinylcholine during the induction of anesthesia. However, most patients who received rocuronium complained of severe burning pain in their arm during intravenous injection. Even after the administration of the induction agents, rocuronium injection can also cause withdrawal of the hand or other generalized movements of the body. We describe a case of gastric regurgitation with pulmonary aspiration following generalized spontaneous movements associated with rocuronium injection in a girl who received pediatric emergent surgery.
authors.affiliation: Department of Anesthesia, Chang Gung Memorial Hospital, Taipei, ROC.
authors.forename: Jiin-Tarng
authors.initials: JT
authors.lastname: Lui
authors.forename: Shin-Jen
authors.initials: SJ
authors.lastname: Huang
authors.forename: Ching-Yue
authors.initials: CY
authors.lastname: Yang
authors.forename: Jee-Ching
authors.initials: JC
authors.lastname: Hsu
authors.forename: Ping-Wing
authors.initials: PW
authors.lastname: Lui
mesh_terms: D000732:Androstanols / Q000008:administration & dosage / Q000009:adverse effects*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D009068:Movement; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects*; D011015:Pneumonia, Aspiration / Q000209:etiology*; D000077123:Rocuronium
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium