title: [Sarcoid granuloma simulating amelanotic melanoma of the iris: a case report].
abstract: We report the case of a unilateral vascular iris tumor in a 24-year-old patient. Clinically, the iris lesion appeared similar to amelanotic melanoma. A systemic work-up (initial check-up), including an angiotensin-converting enzyme determination, provided the diagnosis of sarcoid granuloma. A biopsy confirmation was not needed. We concluded that iris granuloma can be the only ocular manifestation of sarcoidosis and this context is likely to be confused with amelanotic melanoma and metastatic carcinoma.
authors.affiliation: Clinique Ophtalmologique Universitaire, Hôpital de la Croix Rousse, 103, Grande rue de la Croix Rousse, 69004 Lyon, France.
authors.forename: F
authors.initials: F
authors.lastname: Rouberol
authors.forename: N
authors.initials: N
authors.lastname: Duquesne
authors.forename: L
authors.initials: L
authors.lastname: Kodjikian
authors.forename: F
authors.initials: F
authors.lastname: Guerillon
authors.forename: J D
authors.initials: JD
authors.lastname: Grange
mesh_terms: D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D005938:Glucocorticoids; D006099:Granuloma / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007499:Iris Diseases / Q000175:diagnosis* / Q000188:drug therapy; D015811:Iris Neoplasms / Q000175:diagnosis*; D008297:Male; D018328:Melanoma, Amelanotic / Q000175:diagnosis*; D009355:Neomycin / Q000008:administration & dosage / Q000627:therapeutic use; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy; D013997:Time Factors; D014792:Visual Acuity
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D003907:Dexamethasone; D009355:Neomycin