[The hepatic xenobiotic biotransformation system in chronic ethanol intoxication].
Animal experiments have indicated that chronic ethanol intoxication suppresses the activity of microsomal oxidation of enzymes and limits their induction with phenobarbital.
Krasikov
S I
SI
Nikonorov
A A
AA
D000435:Alcoholic Intoxication / Q000209:etiology*; D000818:Animals; D001711:Biotransformation; D000431:Ethanol / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D015262:Xenobiotics / Q000009:adverse effects* / Q000493:pharmacokinetics*
D015262:Xenobiotics; D000431:Ethanol