PET-CT localizes previously undetectable metastatic lesions in recurrent fallopian tube carcinoma.
BACKGROUND
Fallopian tube carcinoma is a rare malignancy that commonly recurs after initial surgical resection. New combined instrumentation with co-registered PET and CT is a new technique that combines functional and anatomic imaging to detect metastatic disease that may be difficult to detect with either modality alone.


METHODS
We present two cases of suspected fallopian tube carcinoma recurrence demonstrating the unique potential of combined PET-CT using 18F-fluoro-2-deoxyglucose (FDG). These cases demonstrate the unique capability to detect and localize metastatic disease when serum CA-125, laparoscopy, and CT scan alone were unable to detect recurrence.


CONCLUSIONS
PET-CT with FDG may prove to be a sensitive and accurate method for detection of metastatic disease and may influence the clinical management of recurrent fallopian tube carcinoma.
Patel
Pavni V
PV
Johns Hopkins Medical Institutions, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Outpatient Center, Baltimore, Maryland 21287, USA.
Cohade
Christian
C
Chin
Bennett B
BB
D000368:Aged; D005185:Fallopian Tube Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000473:pathology; D009367:Neoplasm Staging; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed
D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18