title: Successful treatment of listerial brain abscess: a case report and literature review.
abstract: Listerial brain abscess is extremely rare; only two cases have been reported in Japan. We encountered a female patient with immunoblastic lymphadenopathy, who developed listerial brain abscess after 8 years of treatment with antineoplastic agents and corticosteroids. Brain MRI revealed multiple space occupying lesions, suggesting abscesses which were possibly caused by hematogenous spread of the bacteria. Immediate blood culture enabled early diagnosis, and she entered into complete remission with high-dose ampicillin. Blood culture and brain imaging seem to play a crucial role in making an early diagnosis, and the administration of high dose of antibiotics is recommended for improvement of this disease.
authors.affiliation: Department of Medicine, Yokohama Rosai Hospital for Labour Welfare Corporation, Yokohama.
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Maezawa
authors.forename: Akira
authors.initials: A
authors.lastname: Hirasawa
authors.forename: Tsuyosi
authors.initials: T
authors.lastname: Abe
authors.forename: Harukiyo
authors.initials: H
authors.lastname: Kawamura
authors.forename: Kenji
authors.initials: K
authors.lastname: Sekiguchi
authors.forename: Masaya
authors.initials: M
authors.lastname: Kunimoto
authors.forename: Tadatsugu
authors.initials: T
authors.lastname: Sato
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Wakabayashi
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Nishikawa
mesh_terms: D001922:Brain Abscess / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008088:Listeriosis / Q000188:drug therapy*; D008875:Middle Aged; D010406:Penicillins / Q000627:therapeutic use*; D010878:Piperacillin / Q000627:therapeutic use*; D012074:Remission Induction
chemical_list: D010406:Penicillins; D010878:Piperacillin