Ionol (BHT) produces superoxide anion.
In aqueous medium etiolated wheat seedlings release superoxide anion (O2*-). Interaction of a synthetic antioxidant, butylated hydroxytoluene (BHT, ionol), with oxygen in the aqueous medium is accompanied by O2*- formation. This suggests that under certain conditions BHT behaves as a prooxidant. A natural antioxidant, superoxide dismutase (SOD), and also a wound healing preparation, emulsified denatured placenta (EDP), do not exhibit the prooxidant properties. In contrast to BHT, they reduce O2*- production by the etiolated wheat seedling system.
Smirnova
E G
EG
Institute of Agricultural Biotechnology, Russian Academy of Agricultural Sciences, Moscow, 127550, Russia.
Lyubimov
Yu I
YI
Malinina
T G
TG
Lyubimova
E Yu
EY
Alexandrushkina
N I
NI
Vanyushin
B F
BF
Kolesova
G M
GM
Yaguzhinsky
L S
LS
D000975:Antioxidants / Q000494:pharmacology; D002084:Butylated Hydroxytoluene / Q000737:chemistry / Q000494:pharmacology*; D007700:Kinetics; D016877:Oxidants / Q000494:pharmacology*; D010100:Oxygen / Q000737:chemistry; D010920:Placenta / Q000737:chemistry; D012639:Seeds / Q000187:drug effects / Q000378:metabolism; D013482:Superoxide Dismutase / Q000494:pharmacology; D013481:Superoxides / Q000378:metabolism*; D014908:Triticum / Q000187:drug effects / Q000378:metabolism; D014867:Water / Q000737:chemistry
D000975:Antioxidants; D016877:Oxidants; D014867:Water; D013481:Superoxides; D002084:Butylated Hydroxytoluene; D013482:Superoxide Dismutase; D010100:Oxygen