title: Papillary pneumocytoma of the lung simulating a pleomorphic adenoma.
abstract: A rare case of papillary pneumocytoma of the lung is reported. The immunohistochemical positivities for EMA, cytokeratin and TTF-l strongly support the hypothesis that the neoplastic cells are originated from type 2 pneumocytes. The tumour also presented areas displaying stroma of non-specific mixoid appearance, simulating a benign tumour of the salivary gland type. We propose that these mixoid areas constitute structures of metaplastic origin.
authors.affiliation: Department of Biochemistry and Biophysic F. Cedrangolo, Section of Anatomic Pathology, Second University of Naples, Naples, Italy.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Baldi
authors.forename: Mario
authors.initials: M
authors.lastname: Santini
authors.forename: Giovanni
authors.initials: G
authors.lastname: Vicidomini
authors.forename: Francesco
authors.initials: F
authors.lastname: Ambrosino
authors.forename: Bruno
authors.initials: B
authors.lastname: Vincenzi
authors.forename: Rosaria
authors.initials: R
authors.lastname: Costanzo
authors.forename: Carmen
authors.initials: C
authors.lastname: Di Leo
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Esposito
authors.forename: Angela M
authors.initials: AM
authors.lastname: Groeger
authors.forename: Feliciano
authors.initials: F
authors.lastname: Baldi
mesh_terms: D000236:Adenoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001984:Bronchial Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D018396:Mucin-1 / Q000032:analysis; D009687:Nuclear Proteins / Q000032:analysis; D013902:Radiography, Thoracic; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors / Q000032:analysis; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D018396:Mucin-1; D009687:Nuclear Proteins; D000074482:Thyroid Nuclear Factor 1; D014157:Transcription Factors; D007633:Keratins