title: 5H-furan-2-ones from fungal cultures of Aporpium caryae.
abstract: Four furanones 1-4 with an unusual skeleton containing an acetylene unit, named aporpinones, were isolated from the culture of the basidiomycete Aporpium caryae and their structures were elucidated by spectroscopic methods. Compounds 3 and 4 showed weak to moderate antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Escherichia coli.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina.
authors.forename: Laura M
authors.initials: LM
authors.lastname: Levy
authors.forename: Gabriela M
authors.initials: GM
authors.lastname: Cabrera
authors.forename: Jorge E
authors.initials: JE
authors.lastname: Wright
authors.forename: Alicia M
authors.initials: AM
authors.lastname: Seldes
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D001487:Basidiomycota / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D005663:Furans / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D005663:Furans