The first cobalt catalyzed [2 + 2 + 2] alkyne cyclotrimerization in aqueous medium at room temperature.
Chelate complex 1 (5 mol%) was found to catalyze the [2 + 2 + 2] cyclization of terminal alkynes in good yields in a 80/20 mixture of water and ethanol at room temperature without further activation.
Yong
Li
L
Institut für Organische Chemie, Universität Hannover, Schneiderberg 1B, D-30167 Hannover, Germany.
Butenschön
Holger
H