title: Fetal therapy.
abstract: Over the past 40 years, a small but increasing number of fetal genetic and congenital anomalies has become amenable to in utero treatment. Successful fetal therapies have included open procedures for congenital diaphragmatic hernia, cystadenomatoid malformation of the lung and saccrococygeal teratoma, shunts for uropathies and thoracic fluids, pharmacological therapies for congenital adrenal hyperplasia and neural tube defect prevention, and the stem cell treatment of severe combined immunodeficiency disorder.
authors.affiliation: Columbia University College of Physicians and Surgeons, St Luke's Roosevelt Hospital Center, 1000 10th Avenue, New York, NY 10019, USA.
authors.forename: Mark I
authors.initials: MI
authors.lastname: Evans
authors.forename: Michael R
authors.initials: MR
authors.lastname: Harrison
authors.forename: Alan W
authors.initials: AW
authors.lastname: Flake
authors.forename: Mark P
authors.initials: MP
authors.lastname: Johnson
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000188:drug therapy; D000013:Congenital Abnormalities / Q000601:surgery*; D005260:Female; D005315:Fetal Diseases / Q000601:surgery / Q000628:therapy*; D005333:Fetus / Q000002:abnormalities; D018380:Hematopoietic Stem Cell Transplantation; D006548:Hernia, Diaphragmatic / Q000601:surgery; D006801:Humans; D011247:Pregnancy; D013514:Surgical Procedures, Operative / Q000379:methods