title: [Processes of cyclicity in the course of ulcer disease].
abstract: 4171 cases with exacerbation of peptic ulcer were identified at endoscopic examination of 23,779 patients. Changes in metabolic-trophic processes (MTP) in gastric mucosa (GM) were studied in 210 patients with duodenal ulcer. A complex chronobiological correlation exists between solar activity and progress of peptic ulcer. Cyclic alterations in MTP were detected in GM. Fluctuations were found at all the levels of body functioning--from systemic structures to molecular ones. The data obtained can be used for optimization of preventive measures in ulcer patients.
authors.forename: L S
authors.initials: LS
authors.lastname: Kornilova
authors.forename: E G
authors.initials: EG
authors.lastname: Zhuk
authors.forename: G A
authors.initials: GA
authors.lastname: Nikitin
mesh_terms: D000704:Analysis of Variance; D018450:Disease Progression; D005753:Gastric Mucosa / Q000378:metabolism*; D006801:Humans; D010437:Peptic Ulcer / Q000378:metabolism / Q000473:pathology*; D010507:Periodicity; D019445:Solar Activity