[Evaluation of renal function in children undergoing surgery under general anaesthesia].
47 children (29 boys and 18 girls) aged from 3 to 13 years were examined. The children were operated under general anaesthesia. All children were in good general condition, belonged to anaesthesia risk groups ASA 1 and ASA 2, had no metabolic, endocrinological, haematological diseases nor had renal or hepatic dysfunction. The examined children were divided into two groups with regard to anaesthesia method. 24 healthy children aged 2-16 years were included into control group. Urinary excretion of N-acetyl-beta-D-glucosaminidase (U-NAG), Tamm-Horsfall protein (U-THP), beta 2-microglobulin (U-beta 2-m) and albumins (U-Alb) as indicators of functions of the following nephron structures: glomerular, proximal and distal tubular were assessed. The studies were carried out directly before and on the first day after surgery.


RESULTS
Statistically significant differences between values of examined indicators before and after surgery have not been observed.


CONCLUSIONS
The administered methods of anaesthesia have not negatively influenced renal function in children.
Wikiera-Magott
Irena
I
Katedra i Klinika Nefrologii Pediatrycznej Akademii Medycznej we Wrocławiu.
Hurkacz
Magdalena
M
Kiliś-Pstrusińska
Katarzyna
K
Zielińska
Marzena
M
Zwolińska
Danuta
D
Orzechowska-Juzwenko
Krystyna
K
D000118:Acetylglucosaminidase / Q000652:urine; D000293:Adolescent; D000419:Albuminuria / Q000652:urine; D000556:Ambulatory Surgical Procedures; D000768:Anesthesia, General; D015415:Biomarkers / Q000652:urine; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism*; D007677:Kidney Function Tests; D008297:Male; D009088:Mucoproteins / Q000652:urine; D058949:Uromodulin; D001613:beta 2-Microglobulin / Q000652:urine
D015415:Biomarkers; D009088:Mucoproteins; C548612:UMOD protein, human; D058949:Uromodulin; D001613:beta 2-Microglobulin; C033079:alpha-N-acetyl-D-glucosaminidase; D000118:Acetylglucosaminidase