Novel nucleophilic trifluoromethylation of vicinal diol cyclic sulfates.
[reaction: see text] A novel method for highly regioselective and stereospecific nucleophilic trifluoromethylation of vicinal diol cyclic sulfates, using the reagent derived from reduction of trifluoromethyl iodide by tetrakis(dimethylamino)ethylene (TDAE), is presented.
Takechi
Naoto
N
Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA.
Ait-Mohand
Samia
S
Medebielle
Maurice
M
Dolbier
William R
WR