Cytokinesis: rho and formins are the ringleaders.
Although cytokinesis was first described in the 1830s, the molecular events underlying this key cellular process remain elusive. New results reveal a role for actin polymerization, the small GTPase Rho and formins in cytokinetic ring assembly.
Huckaba
Thomas M
TM
Department of Anatomy and Cell Biology, Columbia University P&S 12-425, 630 West 168th Street, New York, New York 10032, USA.
Pon
Liza A
LA
D000205:Actomyosin / Q000502:physiology; D000818:Animals; D002455:Cell Division / Q000502:physiology*; D012568:Schizosaccharomyces / Q000166:cytology / Q000502:physiology; D020741:rho GTP-Binding Proteins / Q000378:metabolism*
D000205:Actomyosin; D020741:rho GTP-Binding Proteins