title: Acyl-lithiation of olefins: formation of cyclopentenones from 1-lithio-butadienes and CO.
abstract: [reaction: see text] Intramolecular acyl-lithiation of C=C double bonds proceeds following carbonylation of 1-lithio-1,3-dienes with CO to afford 2- or 3-cyclopentenone derivatives in good to excellent yields after hydrolysis. Addition of electrophiles to the carbonylation reaction mixtures affords various multiply substituted cyclopentenones.
authors.affiliation: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
authors.forename: Qiuling
authors.initials: Q
authors.lastname: Song
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Li
authors.forename: Jinglong
authors.initials: J
authors.lastname: Chen
authors.forename: Congyang
authors.initials: C
authors.lastname: Wang
authors.forename: Zhenfeng
authors.initials: Z
authors.lastname: Xi