Outcome of consecutive pregnancies in a patient with Bombay (Oh) blood group.
A young lady with a rare Bombay (Oh) blood group had two successive uneventful pregnancies. Her serum contained a potent high-titre anti-H and serological as well as chemiluminescence tests, suggesting that the antibody was haemolytic. Her husband was of the normal H status. Theoretically, both babies should have been positive for the H antigen and should have suffered from haemolytic disease of the newborn. This apparent conundrum could be owing to the weak expression of the H antigens on the infant red cells.
Bhattacharya
S
S
SpR Haematology, Christie Hospital, Manchester, Bristol, UK.
Makar
Y
Y
Laycock
R A
RA
Gooch
A
A
Poole
J
J
Hadley
A
A
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D004899:Erythroblastosis, Fetal; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000097:blood / Q000276:immunology; D007519:Isoantigens / Q000097:blood / Q000276:immunology; D011247:Pregnancy; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk
D000017:ABO Blood-Group System; D007518:Isoantibodies; D007519:Isoantigens