title: Four cases of panic disorder successfully treated with Kampo (Japanese herbal) medicines: Kami-shoyo-san and Hange-koboku-to.
abstract: Kampo medicines have been used to treat patients with psychogenic disorders from ancient times. In the present report the cases are described of four patients with panic disorder successfully treated with Kampo medicines. These four patients fulfilled the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for panic disorder with agoraphobia. The Kampo medicine Kami-shoyo-san (TJ-24) relieved panic attacks, anticipatory anxiety and agoraphobia in two patients, and Hange-koboku-to (TJ-16) relieved these symptoms in the other two patients. The patients in whom Kami-shoyo-san was effective were older and complained of more symptoms than those in whom Hange-koboku-to was effective. These Kampo medicines may be useful as additional or alternative treatments for panic disorder.
authors.affiliation: Department of Japanese Oriental (Kampo) Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Sugitani, Toyama, Japan. nmantani@showa.gunma-u.ac.jp
authors.forename: Naoki
authors.initials: N
authors.lastname: Mantani
authors.forename: Akito
authors.initials: A
authors.lastname: Hisanaga
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kogure
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kita
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Shimada
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Terasawa
mesh_terms: D000328:Adult; D003679:Deglutition; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D020835:Medicine, Kampo; D008875:Middle Aged; D016584:Panic Disorder / Q000188:drug therapy* / Q000523:psychology; D016896:Treatment Outcome
chemical_list: C120141:Banxia Houpo Tang; D004365:Drugs, Chinese Herbal; C103354:kamisyoyo san