title: Concomitant Cushing's syndrome due to adrenal adenoma in a patient with systemic lupus erythematosus.
abstract: A 51-year-old woman had been administered 5 mg/day of prednisolone due to systemic lupus erythematosus (SLE). She developed hypertension, hypokalemia and a pathologic pubic fracture during two years before admission. Although iatrogenic Cushing's syndrome was initially suspected, we diagnosed her as concomitant Cushing's syndrome due to a left adrenal tumor. The elevated endogeneous glucocorticoids were evaluated from urinary excretions of 17-hydroxycorticosteroids, which was 2-fold higher than normal and equivalent to 10 mg of prednisolone. After laparoscopic left adrenalectomy, SLE was favorably controlled with 15 mg of prednisolone, the dosage of which was equivalent to the estimated amount of preoperative glucocorticoids.
authors.affiliation: Division of Cardiology, Kobe National Hospital, Kobe.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Shimizu
authors.forename: Masahito
authors.initials: M
authors.lastname: Kawata
authors.forename: Toshio
authors.initials: T
authors.lastname: Okada
authors.forename: Housai
authors.initials: H
authors.lastname: Yuu
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Kurahashi
authors.forename: Kunito
authors.initials: K
authors.lastname: Yamanaka
authors.forename: Keiichi
authors.initials: K
authors.lastname: Umezu
mesh_terms: D000236:Adenoma / Q000150:complications*; D000310:Adrenal Gland Neoplasms / Q000150:complications*; D003480:Cushing Syndrome / Q000150:complications / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged