title: Stereoselective transition metal-catalyzed and radical polycyclizations.
abstract: This short review presents a selection of metal-mediated and radical polycyclizations reported during the past two years. Palladium-catalyzed domino processes, cobalt-mediated cycloadditions and Pauson-Khand reactions catalyzed by rhodium are described. Ruthenium and platinum are shown as powerful metal catalysts in cyclizations, ring-closing metathesis and cycloisomerizations. Finally, recent examples of radical cascades, and their synthetic applications, are selected for their ability to build polycyclic compounds.
authors.affiliation: Université Pierre et Marie Curie Laboratoire de Chimie Organique de Synthèse UMR 7611 4 place Jussieu Tour 44-54 2ème étage B 229 75252 Paris, France.
authors.forename: Corinne
authors.initials: C
authors.lastname: Aubert
authors.forename: Christine
authors.initials: C
authors.lastname: Courillon
authors.forename: Anne-Lise
authors.initials: AL
authors.lastname: Dhimane
authors.forename: Louis
authors.initials: L
authors.lastname: Fensterbank
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Lacôte
authors.forename: Serge
authors.initials: S
authors.lastname: Thorimbert
authors.forename: Max
authors.initials: M
authors.lastname: Malacria
mesh_terms: D000818:Animals; D002384:Catalysis / Q000187:drug effects; D005609:Free Radicals / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D008670:Metals / Q000737:chemistry / Q000378:metabolism*; D011083:Polycyclic Compounds / Q000737:chemistry / Q000378:metabolism*; D013237:Stereoisomerism; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D005609:Free Radicals; D008670:Metals; D011083:Polycyclic Compounds