title: Comparative evaluation of Kodak EDR2 and XV2 films for verification of intensity modulated radiation therapy.
abstract: Film dosimetry provides a convenient tool to determine dose distributions, especially for verification of IMRT plans. However, the film response to radiation shows a significant dependence on depth, energy and field size that compromise the accuracy of measurements. Kodak's XV2 film has a low saturation dose (approximately 100 cGy) and, consequently, a relatively short region of linear dose-response. The recently introduced Kodak extended range EDR2 film was reported to have a linear dose-response region extending to 500 cGy. This increased dose range may be particularly useful in the verification of IMRT plans. In this work, the dependence of Kodak EDR2 film's response on the depth, field size and energy was evaluated and compared with Kodak XV2 film. Co-60, 6 MV, 10 MV and 18 MV beams were used. Field sizes were 2 x 2, 6 x 6, 10 x 10, 14 x 14, 18 x 18 and 24 x 24 cm2. Doses for XV2 and EDR2 films were 80 cGy and 300 cGy, respectively. Optical density was converted to dose using depth-corrected sensitometric (Hurter and Driffield, or H&D) curves. For each field size, XV2 and EDR2 depth-dose curves were compared with ion chamber depth-dose curves. Both films demonstrated similar (within 1%) field size dependence. The deviation from the ion chamber for both films was small forthe fields ranging from 2 x 2 to 10 x 10 cm2: < or =2% for 6, 10 and 18 MV beams. No deviation was observed for the Co-60 beam. As the field size increased to 24 x 24 cm2, the deviation became significant for both films: approximately 7.5% for Co-60, approximately 5% for 6 MV and 10 MV, and approximately 6% for 18 MV. During the verification of IMRT plans, EDR2 film showed a better agreement with the calculated dose distributions than the XV2 film.
authors.affiliation: Loyola University Medical Center, Radiation Oncology Department, Maywood, IL 60153, USA. ndogan@rdth.rdth.luhs.org
authors.forename: Nesrin
authors.initials: N
authors.lastname: Dogan
authors.forename: Leonid B
authors.initials: LB
authors.lastname: Leybovich
authors.forename: Anil
authors.initials: A
authors.lastname: Sethi
mesh_terms: D004307:Dose-Response Relationship, Radiation; D019544:Equipment Failure Analysis / Q000379:methods*; D005373:Film Dosimetry / Q000145:classification / Q000295:instrumentation* / Q000379:methods; D008422:Materials Testing / Q000379:methods*; D011786:Quality Control; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation*; D020266:Radiotherapy, Conformal / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity