title: Motor neuron disease presenting with slow saccades and dementia.
abstract: A 46-year-old man with a 2-year history of dementia presented with very slow saccades and tongue fasciculations. The diagnosis of amyotrophic lateral sclerosis (ALS) was established by electrophysiologic studies and ultimately on autopsy. Rarely, slowed saccades may be present in ALS, and slow saccades in a relatively young demented patient should prompt consideration of ALS.
authors.affiliation: Department of Ophthalmology, Suite 601, University of Alabama, 700 South 18th Street, Birmingham, AL 35233, USA.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Vaphiades
authors.forename: Muhammad
authors.initials: M
authors.lastname: Husain
authors.forename: Katalin
authors.initials: K
authors.lastname: Juhasz
authors.forename: James W
authors.initials: JW
authors.lastname: Schmidley
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000473:pathology; D003704:Dementia / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D012438:Saccades; D013116:Spinal Cord / Q000473:pathology