title: Ecthyma gangrenosum: considerations in a previously healthy child.
abstract: Ecthymagangrenosum is a skin lesion that is most commonly caused by. Although ecthyma gangrenosum usually develops in patients with underlying immunodeficiencies or chronic diseases, there have been reports of its appearance in previously healthy children. A review of such patients in the English literature showed that most of them had either previously undetected immunodeficiencies or transient risk factors that predisposed them to the development of ecthyma gangrenosum. We report a patient without apparent antecedent predisposing risk factors for ecthyma gangrenosum who developed chronic neutropenia 1 week after presentation. It is important for the primary care provider to recognize ecthyma gangrenosum, treat it with appropriate antimicrobial agents and investigate the patient for occult immunodeficiencies.
authors.affiliation: Department of Pediatrics, University of Pittsburgh School of Medicine, PA, USA.
authors.forename: Arezoo
authors.initials: A
authors.lastname: Zomorrodi
authors.forename: Ellen R
authors.initials: ER
authors.lastname: Wald
mesh_terms: D000284:Administration, Oral; D002908:Chronic Disease; D002939:Ciprofloxacin / Q000008:administration & dosage; D004473:Ecthyma / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage; D006760:Hospitalization; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D009503:Neutropenia / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D016179:Granulocyte Colony-Stimulating Factor; D002939:Ciprofloxacin