Autologous hematopoietic stem cell transplantation for refractory lymphomatoid granulomatosis.
Lymphomatoid granulomatosis (LG) is a rare lymphoproliferative disorder. There is no standard therapy for refractory patient. Here we present the case of a patient with LG of the lung and the brain who was refractory to polychemotherapy. An autologous hematopoietic stem cell transplantation was done and the patient achieved a complete remission. This represents the first case of high-dose chemotherapy with hematopoietic stem cell support in this disease.
Lemieux
Julie
J
Centre d'Hématologie et d'Immunologie Clinique, Hôpital du St-Sacrement, Université Laval, 1050 Chemin Ste-Foy, Quebec, Que, Canada G1S 4L8.
Bernier
Vincent
V
Martel
Nadine
N
Delage
Robert
R
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis / Q000628:therapy; D003952:Diagnostic Imaging; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000628:therapy; D008230:Lymphomatoid Granulomatosis / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D012074:Remission Induction; D016879:Salvage Therapy; D014182:Transplantation, Autologous