title: [Evaluation of intra-arterial infusion chemotherapy for liver metastasis from colorectal cancer].
abstract: We evaluated the effect of intra-arterial infusion chemotherapy for liver metastasis from colorectal cancer. Of 405 patients undergoing colectomy in our department from July 1993 to February 2002, 38 had liver metastasis. We performed catheterization intra-operatively or postoperatively, and intra-arterial infusion chemotherapy was given for liver metastasis from colorectal cancer. Thirty-eight patients were treated with four different arterial infusion courses that mainly consisted of 5-FU. The 5-year survival rate was 8%. Maximal survival period was 68 months, and mean survival was 22 months. The effective rate was 20% Intra-arterial infusion chemotherapy was a useful treatment for liver metastasis from colorectal cancer. Resection of the liver metastasis was the first choice for operative liver metastases from colorectal cancer, and we performed intra-arterial infusion chemotherapy for patients postoperatively or patients with non-operative liver metastasis.
authors.affiliation: Dept. of Surgery, Tsubame Rosai Hospital.
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Kiyonaga
authors.forename: Kaoru
authors.initials: K
authors.lastname: Miyashita
authors.forename: Kazuya
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Todoroki
authors.forename: Kikuo
authors.initials: K
authors.lastname: Aizawa
authors.forename: Naoki
authors.initials: N
authors.lastname: Okumura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003082:Colectomy; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D015996:Survival Rate