title: Benign intracranial hypertension and thyreostimulin suppression hormonotherapy.
abstract: OBJECTIVE
  To report a case of benign intracranial hypertension occurring during thyreostimulin suppression hormonotherapy after thyroidectomy for papillary cancer.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  A 45-year-old woman underwent total thyroidectomy for a 7-mm papillary cancer. Seventeen years later, she experienced headache, dizziness, irritability, sensation of full head, and blurred vision of the right eye while being treated with a mix of L thyroxin (LT4) and liothyronin (LT3). Ophthalmological data (including the presence of papilledema), cerebroorbital magnetic resonance imaging, and lumbar pressure evaluation confirmed benign intracranial hypertension.
  
  
  RESULTS
  Substitutive hormonotherapy was decreased under specialized surveillance, permitting remission of benign intracranial hypertension symptoms and papilledema.
  
  
  CONCLUSIONS
  Benign intracranial hypertension is usually difficult to cure, and its association with thyroid hormonotherapy is rare. In our patient, tapering LT4 and withdrawal of LT3 until a euthyroidal state was obtained resulted in successful treatment of benign intracranial hypertension.
authors.affiliation: Service de Médecine Interne, Hôpital de la Timone, Marseille, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Serratrice
authors.forename: Brigitte
authors.initials: B
authors.lastname: Granel
authors.forename: John
authors.initials: J
authors.lastname: Conrath
authors.forename: Henri
authors.initials: H
authors.lastname: Dufour
authors.forename: Patrick
authors.initials: P
authors.lastname: Disdier
authors.forename: Jean François
authors.initials: JF
authors.lastname: Henry
authors.forename: Pierre-Jean
authors.initials: PJ
authors.lastname: Weiller
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000601:surgery; D004359:Drug Therapy, Combination; D005260:Female; D006023:Glycoproteins / Q000037:antagonists & inhibitors*; D006801:Humans; D008875:Middle Aged; D010211:Papilledema / Q000139:chemically induced; D011559:Pseudotumor Cerebri / Q000139:chemically induced*; D013964:Thyroid Neoplasms / Q000601:surgery; D013965:Thyroidectomy; D013974:Thyroxine / Q000009:adverse effects*; D014284:Triiodothyronine / Q000009:adverse effects*
chemical_list: D006023:Glycoproteins; C458339:thyrostimulin; D014284:Triiodothyronine; D013974:Thyroxine