Thiazide-induced lichenoid photosensitivity.
We report the case of a 77-year-old male who developed a florid photosensitive eruption while taking thiazide diuretics for heart failure. The lesions were lichenoid in appearance and this was confirmed histologically. The eruption cleared on withdrawal of the drug. Although thiazide-induced photosensitivity is a well-documented phenomenon, there have been no histologically proven cases of a lichenoid eruption in light exposed areas in the recent literature.
Johnston
G A
GA
Department of Dermatology, Leicester Royal Infirmary, Leicester, UK. gjohnston@uhl-tr.nhs.uk
D000368:Aged; D002303:Cardiac Output, Low / Q000188:drug therapy; D002317:Cardiovascular Agents / Q000009:adverse effects*; D017454:Dermatitis, Photoallergic / Q000209:etiology*; D004338:Drug Combinations; D003875:Drug Eruptions / Q000209:etiology*; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects*; D017512:Lichenoid Eruptions / Q000139:chemically induced*; D008297:Male; D014223:Triamterene / Q000009:adverse effects*
D002317:Cardiovascular Agents; D004338:Drug Combinations; D006852:Hydrochlorothiazide; C020743:hydrochlorothiazide-triamterene; D014223:Triamterene