Molecular basis for anti-amyloid therapy in the prevention and treatment of Alzheimer's disease.
Gandy
Sam
S
Farber Institute for Neurosciences, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA. samgandy@earthlink.net
D000544:Alzheimer Disease / Q000503:physiopathology* / Q000517:prevention & control*; D023582:Alzheimer Vaccines; D053829:Amyloid Precursor Protein Secretases; D016564:Amyloid beta-Protein Precursor / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D000686:Amyloidosis / Q000235:genetics / Q000276:immunology / Q000517:prevention & control*; D000818:Animals; D016282:Aspartic Acid Endopeptidases; D010450:Endopeptidases / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects
D023582:Alzheimer Vaccines; D016564:Amyloid beta-Protein Precursor; D004791:Enzyme Inhibitors; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human