title: [The establishment of testicular fibrosis model in Wistar rats].
abstract: OBJECTIVE
  To establish the testicular fibrosis model in rats.
  
  
  METHODS
  Wistar rats were divided into control group(n = 12) and model group(n = 40) randomly. Testicular fibrosis model was built with the classical method of establishing experimental autoimmune orchitis (EAO) combined with injecting Bacille Calmette-Guerin (BCG) into left testis.
  
  
  RESULTS
  The incidence rate of EAO and the rate of testicular fibrosis were 100%, 11.1% and 100%, 81.5% at 80, 140 days after the first infection, respectively.
  
  
  CONCLUSIONS
  The model of rat testicular fibrosis was established successfully.
authors.affiliation: Department of Pathology, Hebei Medical University, Shijiazhuang, Hebei 050017, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Yu-Mei
authors.initials: YM
authors.lastname: Ma
authors.forename: He-Ming
authors.initials: HM
authors.lastname: Xiu
authors.forename: Qu-Sheng
authors.initials: QS
authors.lastname: Zhao
authors.forename: Hui-Chen
authors.initials: HC
authors.lastname: Sun
authors.forename: Zheng
authors.initials: Z
authors.lastname: Xu
authors.forename: Chang-En
authors.initials: CE
authors.lastname: Ben
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000473:pathology*; D004195:Disease Models, Animal; D005355:Fibrosis; D008297:Male; D009163:Mycobacterium bovis; D009920:Orchitis / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D013737:Testis / Q000473:pathology*