Thorotrast-induced cholangiocarcinoma: case report.
Thorotrast, a contrast medium used extensively before being banned in 1950s, delivers a densely ionizing, high linear energy transfer type of radiation that predisposes to malignancies. We report a case of peripheral cholangiocarcinoma and describe its computed tomographic and magnetic resonance imaging features in a patient who developed it 48 years after exposure to Thorotrast.
Sahani
D
D
Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Prasad
S R
SR
Tannabe
K K
KK
Hahn
P F
PF
Mueller
P R
PR
Saini
S
S
D000368:Aged; D018281:Cholangiocarcinoma / Q000139:chemically induced / Q000175:diagnosis*; D003287:Contrast Media / Q000009:adverse effects*; D019786:Gadolinium DTPA; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis*; D013911:Thorium Dioxide / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D013911:Thorium Dioxide; D019786:Gadolinium DTPA