Skin relapse from cervical cancer.
BACKGROUND
Cutaneous lymphangitis carcinomatosis from cervical carcinoma is a very rare form of tumor metastatization; only anecdotal cases are reported in the literature. Most of the patients with skin relapse experienced metastasis as a single or multiple nodules.


METHODS
A case of cutaneous lymphangitis carcinomatosis mimicking contact dermatitis was diagnosed at our institution in a patient affected by cervical carcinoma stage IIB. Palliative chemotherapy with paclitaxel was started and the patient experienced complete clinical response. The hypothetical mechanism of spread and the unusual manifestation of relapse are described.


CONCLUSIONS
In a woman with a history of cervical cancer, a diffuse pruritic skin eruption should alert the clinician to the possibility of cutaneous carcinomatous lymphangitis. If a lymphangitis carcinomatosis is diagnosed, systemic intravenous chemotherapy should be considered.
Palaia
Innocenza
I
Department of Gynaecology, University of Rome Campus Biomedico, Via Longoni 69, 00155 Rome, Italy.
Angioli
Roberto
R
Cutillo
Giuseppe
G
Manci
Natalina
N
Panici
Pierluigi Benedetti
PB
D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D005260:Female; D006801:Humans; D008205:Lymphangitis / Q000473:pathology; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000628:therapy
D017239:Paclitaxel