[Ultrastructural observation of detrusor in BPH patients].
OBJECTIVE
To observe the detrusor ultrastructure in BPH patients and to investigate the relationship between detrusor instability and ultrastructure.


METHODS
The patients were divided into groups of detrusor instability(DI) and detrusor stability(DS) according to urodynamics examination. The structure of the detrusor were observed by light microscopy and transmission electron microscopy(TEM).


RESULTS
The intercellular intermediate junctions and cytoplasmic process junctions in DS were 11.34 +/- 3.23 and 4.26 +/- 1.78 respectively. The intercellular intermediate junctions decreased obviously (3.12 +/- 1.47, P < 0.01) instead of a large amount of cytoplasmic process junctions (26.37 +/- 7.14, P < 0.01) in DI.


CONCLUSIONS
There is a close relevance between intercellular junctions and DI. The observation of the ultrastructure of the detrusor is helpful for the diagnosis of BPH with DI and for the clinical treatment.
Lu
Gen-Sheng
GS
Department of Urology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
Song
Bo
B
Jin
Xi-Yu
XY
Xiong
En-Qing
EQ
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D007365:Intercellular Junctions / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009130:Muscle, Smooth / Q000648:ultrastructure*; D011470:Prostatic Hyperplasia / Q000473:pathology*; D001743:Urinary Bladder / Q000648:ultrastructure*