title: [Solitary plasmacytoma of the sphenoid. A case report].
abstract: A rare case of sphenoidal plasmacytoma in a 79 year-old male patient is reported. The diagnosis was preoperatively considered because of associated dysproteinemia and it was histopathologically confirmed on a transphenoidal biopsy specimen. Initial evaluation disclosed no systemic dissemination of the disease and a solitary plasmacytoma was diagnosed. Radiotherapy was delivered with subsequent clinical improvement and significant tumor reduction was illustrated on follow-up imaging studies. Twenty-two months after diagnosis, the patient remains asymptomatic without evidence of transformation to multiple myeloma. Only 7 comparable cases have been reported in the literature. The diagnostic, pathological and nosographic features of sphenoid plasmacytomas are discussed.
authors.affiliation: Service de Neurochirurgie B, Hopital Neurologique et Neurochirurgical Pierre Wertheimer, 59 boulevard Pinel, BP Lyon-Montchat, 69394 Lyon Cedex 03, France. philippe.bret@chu-lyon.fr
authors.forename: Ph
authors.initials: P
authors.lastname: Bret
authors.forename: H
authors.initials: H
authors.lastname: Stan
authors.forename: N
authors.initials: N
authors.lastname: Streichenberger
authors.forename: C
authors.initials: C
authors.lastname: Sebban
authors.forename: J
authors.initials: J
authors.lastname: Guyotat
mesh_terms: D000368:Aged; D001536:Bence Jones Protein / Q000652:urine; D014408:Biomarkers, Tumor / Q000032:analysis; D004172:Diplopia / Q000209:etiology; D006261:Headache / Q000209:etiology; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D008279:Magnetic Resonance Imaging; D008297:Male; D009363:Neoplasm Proteins / Q000097:blood; D010954:Plasmacytoma / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D012888:Skull Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D013100:Sphenoid Bone
chemical_list: D014408:Biomarkers, Tumor; D007145:Immunoglobulin kappa-Chains; D009363:Neoplasm Proteins; D001536:Bence Jones Protein