title: Limitations of transvaginal sonography for the diagnosis of adenomyosis, with histopathological correlation.
abstract: OBJECTIVE
  To evaluate the accuracy of transabdominal sonography (TAS) and transvaginal sonography (TVS) for the diagnosis of adenomyosis, and to determine the diagnostic relevance of various sonographic criteria.
  
  
  METHODS
  A total of 129 women scheduled for hysterectomy were enrolled into this prospective study. Group 1 (n = 23) consisted of patients with menometrorrhagia who were free of myoma and endometrial disorders on TAS. Group 2 consisted of all the other patients (n = 106). TAS and TVS findings were compared to histopathological results.
  
  
  RESULTS
  The prevalence of adenomyosis in Groups 1 and 2 was 91.3% and 24.5%, respectively. TAS had limited value for the diagnosis of adenomyosis in both groups. The sensitivity, specificity, and positive and negative predictive values of TVS in Groups 1 and 2 were 80.9% and 38.4%, 100% and 97.5%, 100% and 83.3%, and 40% and 82.9%, respectively. The accuracy of combined TAS and TVS in Groups 1 and 2 was 91.3% and 83%, respectively. The presence of myometrial cysts was the most specific ultrasound diagnostic criterion for adenomyosis. Hypoechoic linear myometrial striations related to the presence of myometrial hypertrophy correlated to hormonal status with a sensitivity of 66.6% and a specificity of 100% in Group 1.
  
  
  CONCLUSIONS
  Our results show that TAS has a limited diagnostic capacity for adenomyosis but also that TVS alone was poor in patients with an enlarged uterus. In these cases a combination of TVS and TAS should be used.
authors.affiliation: Department of Radiology, Hôpital Tenon, Paris, France. marc.bazot@tnn.ap-hop-paris.fr
authors.forename: M
authors.initials: M
authors.lastname: Bazot
authors.forename: E
authors.initials: E
authors.lastname: Daraï
authors.forename: J
authors.initials: J
authors.lastname: Rouger
authors.forename: R
authors.initials: R
authors.lastname: Detchev
authors.forename: A
authors.initials: A
authors.lastname: Cortez
authors.forename: S
authors.initials: S
authors.lastname: Uzan
mesh_terms: D000328:Adult; D000368:Aged; D004715:Endometriosis / Q000000981:diagnostic imaging* / Q000473:pathology; D019160:Endosonography / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies