title: Unprecedented highly stereoselective alpha- and beta-C-glycosidation with chiral titanium enolates.
abstract: [reaction: see text] Lewis acid mediated addition of chiral titanium enolates to glycals provides either alpha- or beta-1'-methyl-substituted C-glycosides. This highly stereoselective methodology permits the modular preparation of three of the four possible diastereomers.
authors.affiliation: Departament de Química Orgànica, Universitat de Barcelona, 08028 Barcelona, Catalonia, Spain.
authors.forename: Igor
authors.initials: I
authors.lastname: Larrosa
authors.forename: Pedro
authors.initials: P
authors.lastname: Romea
authors.forename: Fèlix
authors.initials: F
authors.lastname: Urpí
authors.forename: Daniel
authors.initials: D
authors.lastname: Balsells
authors.forename: Jaume
authors.initials: J
authors.lastname: Vilarrasa
authors.forename: Mercè
authors.initials: M
authors.lastname: Font-Bardia
authors.forename: Xavier
authors.initials: X
authors.lastname: Solans
mesh_terms: D006027:Glycosides; D007659:Ketones; D009005:Monosaccharides / Q000138:chemical synthesis*; D013237:Stereoisomerism; D014025:Titanium
chemical_list: C438934:C-glycoside; D006027:Glycosides; D007659:Ketones; D009005:Monosaccharides; D014025:Titanium