title: [Effect of gamma-aminobutyric acid on the sperm acrosin activity].
abstract: OBJECTIVE
  To investigate the effect of gamma-aminobutyric acid (GABA) on the sperm acrosin activity in normal men and positive antisperm antibody (AsAb) men.
  
  
  METHODS
  Sperm acrosin activity was detected by BAEE/ADH method.
  
  
  RESULTS
  GABA could increase the sperm acrosin activity in normal and AsAb positive patients (P < 0.01). The results also indicated that GABA significantly increased Na(+)-K(+)-ATPase activity (P < 0.01), Ca(2+)-ATPase activity (P < 0.05) and SOD activity (P < 0.01) of sperm.
  
  
  CONCLUSIONS
  The results demonstrated that GABA could influence the sperm acrosin activity.
authors.affiliation: Department of Physiology, Harbin Medical University, Harbin, Heilongjiang 150086, China.
authors.forename: Shu-Ling
authors.initials: SL
authors.lastname: Bian
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Zhu
authors.forename: Jiang
authors.initials: J
authors.lastname: Ni
authors.forename: Lan-Chun
authors.initials: LC
authors.lastname: Yao
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
mesh_terms: D000176:Acrosin / Q000378:metabolism*; D006801:Humans; D008297:Male; D013094:Spermatozoa / Q000187:drug effects* / Q000276:immunology / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
chemical_list: D005680:gamma-Aminobutyric Acid; D000176:Acrosin