title: Quantitative sensory testing: high sensitivity in small fiber neuropathy with normal NCS/EMG.
abstract: We evaluated the diagnostic sensitivity of quantitative sensory testing (QST), using the CASE IV system, in 14 patients with clinically diagnosed small-fiber neuropathy and normal traditional electrodiagnostic studies. All patients had at least 1 abnormal threshold, 13 patients had abnormal heat-pain thresholds, 8 had abnormal cold thresholds, and 7 had abnormal vibration thresholds. QST is therefore highly effective in documenting dysfunction in small fiber neuropathy patients.
authors.affiliation: Peripheral Neuropathy Center, Department of Neurology and Neuroscience, Weill Medical College of Comell University, New York, NY 10022, USA.
authors.forename: Paul
authors.initials: P
authors.lastname: Magda
authors.forename: Norman
authors.initials: N
authors.lastname: Latov
authors.forename: Michelle V
authors.initials: MV
authors.lastname: Renard
authors.forename: Howard W
authors.initials: HW
authors.lastname: Sander
mesh_terms: D000328:Adult; D004576:Electromyography / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000502:physiology*; D009422:Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology*; D017288:Pain Threshold / Q000502:physiology; D012189:Retrospective Studies