[Discovery of two sub-types of Hantanvirus in Anhui mountain areas].
OBJECTIVE
To investigate the existence of hemorrhagic fever with renal syndrome (HFRS) foci in high mountains and forest areas.


METHODS
A survey was conducted in the areas of 1 400 meter altitude in Dabie mountain and of 1,600 meter altitude in Wannan mountain in the mid 1990's using methods related to epidemiology, geographic-epidemiology, serum epidemiology, pathogenic and molecular epidemiology.


RESULTS
Two strains of HFRS viruses were isolated from pulmonary tissues of Rattus niviventer and both of them were identified as A types. The analysis of the nuclei sequence showed that there were significant differences between both sub types and HTN 76-118.


CONCLUSIONS
It was confirmed that there were HFRS foci in the areas with 2 strains possible new sub-types of HFRS.
Luo
Zhaozhuang
Z
Anhui Anti-Epidemic Station, Hefei 230061, China.
Liu
Yan
Y
Liu
Hong
H
Wang
Yiyin
Y
Zhao
Yueping
Y
D000818:Animals; D002681:China; D018063:Hantaan virus / Q000145:classification* / Q000235:genetics; D009115:Muridae / Q000821:virology*; D051381:Rats; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012703:Serotyping