title: Plasma organochlorine concentrations in endurance athletes and obese individuals.
abstract: OBJECTIVE
  Organochlorines are lipophilic compounds that are ingested with food and that accumulate in adipose tissue. Their plasma concentrations were compared in three groups of individuals with different body fatness characteristics: endurance athletes, lean sedentary subjects, and obese individuals.
  
  
  METHODS
  The relationship between body fat mass and total plasma organochlorine concentration adjusted for age was analyzed by pooling data of sedentary lean and obese subjects. The regression equation derived from this analysis was also used to predict residual scores of total organochlorine concentrations in trained individuals, which were compared to measured values in these subjects.
  
  
  RESULTS
  Plasma organochlorine concentrations tended to be lower in athletes in comparison with values measured among lean sedentary individuals. Their concentrations were higher in obese individuals than in lean sedentary subjects and athletes. Total plasma organochlorine concentration was positively associated to body fat mass in the sedentary group (lean and obese combined, reference population).
  
  
  CONCLUSIONS
  Large adipose tissue compartment such as observed in obese individuals is associated with increased levels of circulating organochlorines, whereas leaner sedentary and trained persons have a lower plasma concentration of these compounds.
authors.affiliation: Physical Activity Sciences Laboratory and Division of Kinesiology, PEPS and Department of Food Science and Nutrition, Laval University, Ste-Foy (Québec), Canada.
authors.forename: Catherine
authors.initials: C
authors.lastname: Pelletier
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Després
authors.forename: Angelo
authors.initials: A
authors.lastname: Tremblay
mesh_terms: D000273:Adipose Tissue / Q000502:physiology; D000368:Aged; D001823:Body Composition / Q000502:physiology; D015992:Body Mass Index; D001835:Body Weight / Q000502:physiology; D006801:Humans; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides / Q000097:blood*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000503:physiopathology*; D010807:Physical Endurance / Q000502:physiology*; D011237:Predictive Value of Tests; D013177:Sports
chemical_list: D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D008055:Lipids