[Drug-induced acute pancreatitis: a personal contribution].
Drugs are commonly considered a rare cause of acute pancreatitis but there are an increasing number of reports of numerous medications that seem to be involved in the pathogenesis of acute pancreatitis with different degrees of causative relationship to the disease (definite--probable--possible). The number of drugs that have been associated to date with acute pancreatitis exceeds 260. The authors report here on their personal series of four cases of drug-induced acute pancreatitis (warfarin, lysinopril/hydrochlorothiazide, lamivudine/stavudine/indinavir, valproic acid), focusing on a number of epidemiological and clinical aspects.
Battillocchi
Barbara
B
Dipartimento di Chirurgia Generale, Specialità Chirurgiche e Trapianti d'Organo Paride Stefanini, Università degli Studi di Roma La Sapienza, Azienda Policlinico Umberto I, Roma.
Diana
Massimo
M
Dandolo
Rossella
R
Stefanini
Silvano
S
D'Amore
Linda
L
Negro
Paolo
P
D000208:Acute Disease; D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D019380:Anti-HIV Agents / Q000009:adverse effects*; D000925:Anticoagulants / Q000009:adverse effects*; D000927:Anticonvulsants / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D004232:Diuretics; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage / Q000009:adverse effects; D019469:Indinavir / Q000009:adverse effects; D019259:Lamivudine / Q000009:adverse effects; D017706:Lisinopril / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis; D049993:Sodium Chloride Symporter Inhibitors / Q000008:administration & dosage / Q000009:adverse effects; D018119:Stavudine / Q000009:adverse effects; D013997:Time Factors; D014635:Valproic Acid / Q000009:adverse effects*; D014859:Warfarin / Q000009:adverse effects*
D000806:Angiotensin-Converting Enzyme Inhibitors; D019380:Anti-HIV Agents; D000925:Anticoagulants; D000927:Anticonvulsants; D000959:Antihypertensive Agents; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D006852:Hydrochlorothiazide; D019259:Lamivudine; D014859:Warfarin; D019469:Indinavir; D014635:Valproic Acid; D018119:Stavudine; D017706:Lisinopril