title: Long-term effects of spinal cord stimulation and coronary artery bypass grafting on quality of life and survival in the ESBY study.
abstract: OBJECTIVE
  To assess the long-term outcome regarding quality of life and survival in patients who were included in the ESBY study 1992-1995. The ESBY study (Electrical Stimulation versus Coronary Artery Bypass Surgery in Severe Angina Pectoris) included 104 patients-with severe angina, increased surgical risk and no prognostic benefits from revascularization-randomized to coronary artery bypass grafting or spinal cord stimulation.
  
  
  RESULTS
  The ESBY patients' quality of life was analysed using two questionnaires, and 5-year mortality was assessed. Quality of life improved significantly 6 months after spinal cord stimulation and coronary artery bypass grafting, respectively, compared to run-in (P<0.001). The results were consistent after 4.8 years. The 5-year mortality was 27.9%. There were no significant differences between the groups.
  
  
  CONCLUSIONS
  Spinal cord stimulation as well as coronary artery bypass grafting offered long-lasting improvement in quality of life. Survival up to 5 years was comparable between the groups. Both methods can be considered as effective treatment options for patients with severe angina, increased surgical risks and estimated to have no prognostic benefits from coronary artery bypass grafting.
authors.affiliation: Multidisciplinary Pain Center, Sahlgrenska University Hospital/Ostra, Göteborg, Sweden.
authors.forename: O
authors.initials: O
authors.lastname: Ekre
authors.forename: T
authors.initials: T
authors.lastname: Eliasson
authors.forename: H
authors.initials: H
authors.lastname: Norrsell
authors.forename: P
authors.initials: P
authors.lastname: Währborg
authors.forename: C
authors.initials: C
authors.lastname: Mannheimer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000628:therapy*; D001026:Coronary Artery Bypass / Q000379:methods*; D004599:Electric Stimulation Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D016019:Survival Analysis