title: Biliary obstruction in metastatic disease: thin-section helical CT findings.
abstract: BACKGROUND
  We describe the thin-section helical computed tomographic (CT) findings of biliary obstruction caused by metastasis.
  
  
  METHODS
  Thin-section helical CT (5 mm slice thickness, 1:1 pitch, portal phase) and direct cholangiography in 50 consecutive patients with biliary obstruction caused by metastases were reviewed retrospectively by three radiologists. The primary sites were the stomach ( n = 36), colon ( n = 12), jejunum ( n = 1), and uterus ( n = 1). The level of biliary obstruction was analyzed with the Bismuth classification, and the CT findings of biliary obstruction were classified into six types: small (<2 cm) periductal masses, large (>/=2 cm) periductal masses, extrinsic compression by a metastatic liver mass, high-attenuation intraductal mass, intrapancreatic mass, and no demonstrable lesion.
  
  
  RESULTS
  The level of biliary obstruction was the hilum in 18 patients (36%), the proximal common duct in 20 (40%), the distal common duct in five (10%), and the periampullary area in seven (14%). Of 18 hilar obstructions, tumor involvement of the secondary confluence of intrahepatic bile ducts was seen in 10 (right in six, left in one, and bilateral in three). Periductal masses were seen in 68% (small in 18, large in 16). In one patient (2%), a large metastatic mass of the liver resulted in extrinsic compression and biliary obstruction. Lesions mimicking primary biliary or pancreatic tumor were seen in four, respectively. In seven, we found no obstructing lesion on CT.
  
  
  CONCLUSIONS
  Biliary obstruction in patients with known primary malignancies can show atypical patterns mimicking primary pancreatobiliary malignancies on thin-section helical CT.
authors.affiliation: Department of Radiology, Seoul National University College of Medicine, Chongno-gu, Seoul 110-744, Korea.
authors.forename: S G
authors.initials: SG
authors.lastname: Moon
authors.forename: J K
authors.initials: JK
authors.lastname: Han
authors.forename: T K
authors.initials: TK
authors.lastname: Kim
authors.forename: A Y
authors.initials: AY
authors.lastname: Kim
authors.forename: T J
authors.initials: TJ
authors.lastname: Kim
authors.forename: B I
authors.initials: BI
authors.lastname: Choi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001650:Bile Duct Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000556:secondary*; D002779:Cholestasis / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology; D036542:Tomography, Spiral Computed; D014057:Tomography, X-Ray Computed; D014594:Uterine Neoplasms / Q000473:pathology