title: Synthesis of 2-arylbenzo[b]furans via copper(I)-catalyzed coupling of o-iodophenols and aryl acetylenes.
abstract: [reaction: see text] We report a copper(I)-catalyzed procedure for the synthesis of 2-arylbenzo[b]furans. This protocol can be used to synthesize a variety of 2-arylbenzo[b]furans in good to excellent yields. This method can tolerate a variety of functional groups, does not require the use of expensive additives, and is palladium-free.
authors.affiliation: Department of Chemistry, University of Massachusetts-Amherst, 710 North Pleasant Street, Amherst, Massachusetts 01003, USA.
authors.forename: Craig G
authors.initials: CG
authors.lastname: Bates
authors.forename: Pranorm
authors.initials: P
authors.lastname: Saejueng
authors.forename: Jaclyn M
authors.initials: JM
authors.lastname: Murphy
authors.forename: D
authors.initials: D
authors.lastname: Venkataraman
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001572:Benzofurans / Q000138:chemical synthesis*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D007462:Iodobenzenes / Q000737:chemistry
chemical_list: D000480:Alkynes; D001572:Benzofurans; D007462:Iodobenzenes; D003300:Copper