title: Selective functionalization of small organic molecules using electrophilic nitrogen sources.
abstract: Selective functionalization of small organic molecules using electrophilic nitrogen-containing reagents has been a long-standing challenge in organic synthesis. The delivery of nitrogen in the corresponding reactions can occur via a nitrenoid, radical or electrophilic pathway. Nitrogen transfer processes result in the rapid synthesis of diverse and useful products, such as aziridines, aminohalides, aminoalcohols, sulfimines and amines. This review outlines advances in the field during the past two years.
authors.affiliation: Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St George Street, Toronto, M5S 3H6, Canada.
authors.forename: Iain D G
authors.initials: ID
authors.lastname: Watson
authors.forename: Andrei K
authors.initials: AK
authors.lastname: Yudin
mesh_terms: D000818:Animals; D006801:Humans; D009584:Nitrogen / Q000737:chemistry / Q000378:metabolism*; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis* / Q000378:metabolism*; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D004364:Pharmaceutical Preparations; D009584:Nitrogen