title: The effect of Mangifera indica stem bark and Pluchea ovalis roots on tracheal smooth muscle in vitro.
abstract: Aqueous extract of the stem bark of Mangifera indica and ethanolic extract of the roots of Pluchea ovalis has been studied on rat tracheal smooth muscle in vitro. The extract of M. indica at 1, 2 and 4 mg/ml and that of P. ovalis at 0.25, 0.5 and 1 mg/ml relaxed, dose-dependently, the rat tracheal smooth muscle strip previously contracted by acetylcholine at 0.055 mmol/l.
authors.affiliation: Département de Physiologie/Pharmacologie Faculté des Sciences, Université de Lomé BP, 1515 Lomé, Togo.
authors.forename: Amégnona
authors.initials: A
authors.lastname: Agbonon
authors.forename: Kwashie
authors.initials: K
authors.lastname: Eklu-Gadegbeku
authors.forename: Kodjo
authors.initials: K
authors.lastname: Aklikokou
authors.forename: Komlan
authors.initials: K
authors.lastname: Essien
authors.forename: Koffi
authors.initials: K
authors.lastname: Akpagana
authors.forename: Messanvi
authors.initials: M
authors.lastname: Gbeassor
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D016015:Logistic Models; D031022:Mangifera / Q000737:chemistry*; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D051381:Rats; D014132:Trachea / Q000187:drug effects*
chemical_list: D010936:Plant Extracts; D000109:Acetylcholine