Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors.
Stahl
Petra
P
Max-Planck-Institut für molekulare Physiologie, Abteilung Chemische Biologie, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.
Kissau
Lars
L
Mazitschek
Ralph
R
Giannis
Athanassios
A
Waldmann
Herbert
H
D000595:Amino Acid Sequence; D020533:Angiogenesis Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D020650:Combinatorial Chemistry Techniques; D004224:Diterpenes / Q000737:chemistry* / Q000494:pharmacology; D008969:Molecular Sequence Data; D009389:Neovascularization, Pathologic / Q000188:drug therapy; D011809:Quinones / Q000737:chemistry* / Q000494:pharmacology; D020794:Receptor Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors* / Q000235:genetics; D017526:Receptor, IGF Type 1 / Q000037:antagonists & inhibitors* / Q000235:genetics; D042787:Receptor, TIE-2; D016415:Sequence Alignment; D040321:Vascular Endothelial Growth Factor Receptor-3 / Q000037:antagonists & inhibitors* / Q000235:genetics
D020533:Angiogenesis Inhibitors; D004224:Diterpenes; D011809:Quinones; D020794:Receptor Protein-Tyrosine Kinases; D017526:Receptor, IGF Type 1; D042787:Receptor, TIE-2; D040321:Vascular Endothelial Growth Factor Receptor-3