5H-furan-2-ones from fungal cultures of Aporpium caryae.
Four furanones 1-4 with an unusual skeleton containing an acetylene unit, named aporpinones, were isolated from the culture of the basidiomycete Aporpium caryae and their structures were elucidated by spectroscopic methods. Compounds 3 and 4 showed weak to moderate antibacterial activity against Bacillus subtilis, Staphylococcus aureus and Escherichia coli.
Levy
Laura M
LM
Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina.
Cabrera
Gabriela M
GM
Wright
Jorge E
JE
Seldes
Alicia M
AM
D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D001487:Basidiomycota / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D005663:Furans / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D005663:Furans