[Relationship between risk factors for coronary artery disease and thallium-201 myocardial scintigraphy].
OBJECTIVE
To investigate the relation of 5 major risk factors (hypertension, diabetes, hyperlipidemia, overweight, smoking) of coronary artery disease (CAD) to the findings from thallium-201 single photon emission computed tomography.


METHODS
Exercise 201TI myocardial scintigraphy was performed in 346 patients with clinically suspected CAD, who were divided into no risk, low risk, moderate risk, and high risk groups, based on CAD risk scores.


RESULTS
The rate of thallium-201 perfusion abnormalities in no risk, low risk, moderate risk, and high risk groups were 48.1%, 70.6%, 89% and 100%, respectively, showing significant difference between them (X2=49.6, P=0.000 1). In patients with CAD risk factors, significant relation was found between the risk scores and semiquantitative scores, lung-to-heart ratios or segment abnormalities (0.133  r  0.450, 0.000 1  P  0.031).


CONCLUSIONS
A close relation between CAD risk factors and thallium-201 myocardial scintigraphy is found. Routine thallium-201 myocardial scintigraphy should be performed in patients clinically suspected of coronary artery disease with CAD risk factors, especially those with moderate to high risk factors.
Ouyang
Wei
W
Department of Nuclear Medicine, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. oyw88@163.net
He
Guo-Rong
GR
Liu
Jin-Hua
JH
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
D013794:Thallium Radioisotopes