[The change of immunoglobulin in patients with eyeball perforation at high altitude].
OBJECTIVE
To explore the change of tear immune function on eyeballs with perforating injury at high altitude.


METHODS
In 51 patients (53 eyes) with eyeball perforating injury at high altitude (sea level 3658 m), by using single agar immune diffusion test, IgG, IgA, IgM, C(3) and C(4) values of tears were separately measured before and after clinical cure.


RESULTS
The Ig values of tears increased universally. The IgA value increased especially in the 7th day. The IgG and IgM value in the serum increased in the 3rd day after injury (P < 0.05), and the IgG, IgA and IgM of tears increased especially on the 7th day (P < 0.01). The C(3) and C(4) value of tears did not change significantly (P < 0.05).


CONCLUSIONS
The change of Ig value is a useful detective means to evaluate the treatment effect.
Chen
Changjiu
C
Department of Ophthalmology, The General Hospital of Tibet Military Command, Lasa 850003, China. stella_cx@hotmail.com
Shi
Quangui
Q
Guo
Lingchang
L
Zhang
Hongmin
H
Deng
Zhiwu
Z
Lu
Lu
L
Ma
Yuebin
Y
Pu
Rong
R
D000293:Adolescent; D000328:Adult; D000531:Altitude; D002648:Child; D003176:Complement C3 / Q000378:metabolism; D003181:Complement C4 / Q000378:metabolism; D015807:Eye Injuries, Penetrating / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000378:metabolism; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism; D007075:Immunoglobulin M / Q000097:blood / Q000378:metabolism; D007136:Immunoglobulins / Q000097:blood / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D013666:Tears / Q000276:immunology
D003176:Complement C3; D003181:Complement C4; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins