title: Undifferentiated leiomyosarcoma showing various sarcomatous components with incidental B-cell lymphoma after tumor recurrence.
abstract: We report a rare case of undifferentiated leiomyosarcoma (LMS) with incidental B-cell lymphoma in a 70-year-old woman. T2-weighted magnetic resonance images revealed a high signal intensity mass measuring 9 x 8 cm in the gluteus muscle. The pathological diagnosis of repeated surgery was undifferentiated LMS that included various sarcomatous components, such as fibrosarcomatous, rhabdomyosarcomatous, and malignant fibrous histiocytoma-like elements. A specimen from a supraclavicular lymph node showed the characteristics of malignant B-cell lymphoma (follicle type). Adjuvant chemotherapy or radiation therapy was not performed because of the patient's advanced age. The patient died from liver metastasis and dysfunction 5 years 8 months after the initial therapy. This is a rare case of LMS with malignant lymphoma. Considerable debate remains whether the B-cell lymphoma developed incidentally.
authors.affiliation: Department of Orthopaedic Surgery, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kanamori
authors.forename: Kazuo
authors.initials: K
authors.lastname: Ohmori
authors.forename: Shigeharu
authors.initials: S
authors.lastname: Nogami
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Maeda
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000150:complications / Q000473:pathology*; D016393:Lymphoma, B-Cell / Q000150:complications / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D019042:Muscle Neoplasms / Q000150:complications / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*