title: Therapeutic options in the management of strictures in Crohn's disease.
abstract: Intestinal strictures are a commonly encountered problem in patients with Crohn's disease. Endoscopic management with hydrostatic balloon dilation is an effective alternative to surgery in patients with endoscopically accessible lesions that are shorter than 7-8 cm. Endoscopic balloon dilation is the preferred initial modality in anastomotic strictures. The presence of inflammation near the stricture should not be considered a contraindication to dilation, and intralesional steroid injection should be considered in these patients with inflammation present in the area of the stricture. Further technological developments in endoscopes and balloon dilators may allow for broader application of these techniques.
authors.affiliation: Dr. Henry D. Janowitz Division of Gastroenterology, Mount Sinai School of Medicine, 1751 York Avenue, New York, NY 10012, USA.
authors.forename: Peter E
authors.initials: PE
authors.lastname: Legnani
authors.forename: Asher
authors.initials: A
authors.lastname: Kornbluth
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology; D002404:Catheterization; D003110:Colonic Neoplasms / Q000209:etiology; D003251:Constriction, Pathologic; D003424:Crohn Disease / Q000150:complications* / Q000601:surgery; D004380:Duodenal Obstruction / Q000209:etiology / Q000628:therapy; D016099:Endoscopy, Gastrointestinal; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D015552:Injections, Intralesional; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D012307:Risk Factors; D015607:Stents
chemical_list: D005938:Glucocorticoids