title: Eosinophilic diseases in two Cavalier King Charles spaniels.
abstract: This report describes the clinical presentation of two Cavalier King Charles spaniels with different eosinophilic diseases. The first case presented with dyspnoea and a non-productive cough, and investigations demonstrated eosinophilic bronchopneumonopathy. The second dog was referred for the investigation of haemorrhagic vomiting and diarrhoea and was eventually diagnosed with eosinophilic enteritis. Both dogs had concurrent eosinophilic stomatitis, and both responded completely to immunosuppressive glucocorticoid therapy. This report is the first to describe the concurrence of eosinophilic stomatitis and systemic eosinophilic disease in Cavalier King Charles spaniels, and suggest that this breed may be predisposed to eosinophilic syndromes.
authors.affiliation: Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU.
authors.forename: A J
authors.initials: AJ
authors.lastname: German
authors.forename: D J
authors.initials: DJ
authors.lastname: Holden
authors.forename: E J
authors.initials: EJ
authors.lastname: Hall
authors.forename: M J
authors.initials: MJ
authors.lastname: Day
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D001947:Breeding; D018893:Bronchoalveolar Lavage / Q000662:veterinary; D001999:Bronchoscopy / Q000662:veterinary; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology / Q000662:veterinary; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000652:urine; D004285:Dogs; D004417:Dyspnea / Q000209:etiology / Q000662:veterinary; D005260:Female; D011239:Prednisolone / Q000627:therapeutic use; D011657:Pulmonary Eosinophilia / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D013280:Stomatitis / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D013577:Syndrome; D016482:Urinalysis / Q000662:veterinary; D014839:Vomiting / Q000209:etiology / Q000662:veterinary
chemical_list: D011239:Prednisolone