title: [Evaluation of myometrial invasion in endometrial carcinoma].
abstract: OBJECTIVE
  To determine the value of preoperative ultrasound, intraoperative gross visual inspection and postoperative bulk specimen measurement in evaluating the diagnosis of myometrial invasion in endometrial carcinoma.
  
  
  METHODS
  A total of 133 cases of women with endometrial carcinoma were analyzed focusing on evaluating the diagnosis of myometrial invasion by preoperative ultrasound, intraoperative gross visual inspection and postoperative bulk specimen measurement. The relationship between CA(125) and endometrial carcinoma of 91 cases of endometrial carcinoma was also analyzed.
  
  
  RESULTS
  In the diagnosis of myometrial invasion and deep myometrial invasion, ultrasound showed a sensitivity of 62.6% and 47.8% and a specificity of 67.7% and 90.0%, respectively, and intraoperative gross visual inspection showed a sensitivity of 59.6% and 73.9% and a specificity of 76.5% and 94.6%, respectively. The sensitivity of postoperative bulk specimen measurement was 70.0% and 94.4% and the specificity was 92.0% and 97.7%, respectively. The levels of CA(125) had no correlation with depth of myometrial invasion in endometrial carcinoma, but they had correlation with International Federation of Gynecology and Obstetrics (FIGO) stage.
  
  
  CONCLUSIONS
  Preoperative ultrasound, intraoperative gross visual inspection and postoperative bulk specimen measurement were helpful to the diagnosis of depth of myometrial invasion in endometrial carcinoma, and postoperative bulk specimen measurement seems to be better. CA(125) could not evaluate depth of myometrial invasion in endometrial carcinoma.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Peng
authors.forename: Keng
authors.initials: K
authors.lastname: Shen
authors.forename: Jinghe
authors.initials: J
authors.lastname: Lang
authors.forename: Huifang
authors.initials: H
authors.lastname: Huang
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Quancai
authors.initials: Q
authors.lastname: Cui
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Tan
mesh_terms: D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D009215:Myometrium / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D014463:Ultrasonography