Plasticity of the kinomes in monkey and rat tissues.
The Kinetworks KPKS 1.0 immunoblotting screen was used to investigate the differential expression of 58 protein serine-threonine kinases, five protein threonine-tyrosine kinases, and 15 other nonreceptor protein tyrosine kinases in three types of human blood cells, 14 monkey organs, and six rat organs. The results demonstrate striking differences in the kineome profiles of diverse organs and even between the same organs in different species.
Pelech
Steven
S
Kinexus Bioinformatics Corporation, Vancouver, BC, Canada. spelech@kinexus.ca
Zhang
Hong
H
D000818:Animals; D015971:Gene Expression Regulation, Enzymologic / Q000235:genetics; D006801:Humans; D008253:Macaca mulatta; D009928:Organ Specificity / Q000235:genetics; D011494:Protein Kinases / Q000235:genetics*; D011499:Protein Processing, Post-Translational / Q000235:genetics; D020543:Proteome / Q000235:genetics*; D051381:Rats
D020543:Proteome; D011494:Protein Kinases