title: Direct detection of radical cations of NADH analogues.
abstract: The radical cation of an NADH analogue (BNAH: 1-benzyl-1,4-dihydronicotinamide) has been successfully detected as the transient absorption and ESR spectra in the thermal electron transfer from BNAH to Fe(bpy)33+ (bpy = 2,2'-bipyridine). The ESR spectra of the radical cations of BNAH and the dideuterated compound (BNAH-4,4'-d2) indicate that the observed radical cation is the keto form rather than the enol form in the tautomerization. The deprotonation rate and the kinetic isotope effects of the keto form of BNAH*+ were determined from the kinetic analysis of the electron-transfer reactions.
authors.affiliation: Department of Material and Life Science, Graduate School of Engineering, CREST, JST, Osaka University, Suita, Osaka 565-0871, Japan. fukuzumi@ap.chem.eng.osaka-u.ac.jp
authors.forename: Shunichi
authors.initials: S
authors.lastname: Fukuzumi
authors.forename: Osamu
authors.initials: O
authors.lastname: Inada
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Suenobu
mesh_terms: D002412:Cations / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D004583:Electrons; D005609:Free Radicals / Q000737:chemistry; D009243:NAD / Q000031:analogs & derivatives* / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: C445701:1-benzyl-1,4-dihydronicotinamide; D002412:Cations; D005609:Free Radicals; D009243:NAD