title: Zebrafish as an immunological model system.
abstract: Two decades of research have established the zebrafish (Danio rerio) as a significant model system for studying vertebrate development and gene structure-function relationships. Recent advances in mutation screening, the creation of genomic resources, including the Zebrafish Genome Project and the development of efficient transgenesis procedures, make this model increasingly attractive for immunological study.
authors.affiliation: Department of Biology, University of South Florida, 4202 East Fowler Avenue, Tampa, FL 33620, USA.
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Yoder
authors.forename: Michael E
authors.initials: ME
authors.lastname: Nielsen
authors.forename: Chris T
authors.initials: CT
authors.lastname: Amemiya
authors.forename: Gary W
authors.initials: GW
authors.lastname: Litman
mesh_terms: D000818:Animals; D005393:Fish Diseases / Q000276:immunology; D007110:Immunity, Active / Q000235:genetics; D007113:Immunity, Innate / Q000502:physiology; D007694:Killer Cells, Natural / Q000276:immunology; D023421:Models, Animal; D018448:Models, Immunological; D016296:Mutagenesis; D019076:Transgenes; D015027:Zebrafish / Q000235:genetics / Q000276:immunology*