title: How should we quantify asthma control? A proposal.
abstract: BACKGROUND
  Current asthma guidelines suggest a series of criteria to assess if asthma is controlled. However, there is a need to develop a simple and practical method to quantify the degree of such control, both in clinical practice and research.
  
  
  OBJECTIVE
  This report describes a new method to quantify asthma control based on a percentage score. It also aims at comparing the percentage scores obtained with patient's self-evaluation of asthma control and a current validated Mini Asthma Quality of Life (MAQOL) questionnaire.
  
  
  METHODS
  Forty-two subjects (25 female and 17 male patients) with asthma of different severity recruited from a tertiary center asthma clinic.
  
  
  METHODS
  The asthma scoring method provided a percentage control for symptoms, baseline expiratory flows and, an optional parameter, for airway inflammation assessed from induced-sputum eosinophil count. These control parameters were compared to an overall assessment of asthma control by the patient (also on a 100% scale) and the score obtained from a validated MAQOL questionnaire.
  
  
  RESULTS
  Mean +/- SEM scores for symptoms, expiratory flows, and airway eosinophilia (last 2 weeks) were 87.8 +/- 1.4%, 88.6 +/- 1.8%, and 66.2 +/- 3.9%, respectively. No significant correlation was found between these three parameters (p > 0.05). The mean global asthma control score and the score estimated by the patient were 80.9 +/- 1.5% and 91.7 +/- 1.5%, respectively (not significantly different). There was a significant correlation between asthma control score (percentage) and percentage symptom score (p < 0.001), while it almost achieved significance for FEV(1) (p = 0.05). Only symptom scores correlated with the MAQOL questionnaire.
  
  
  CONCLUSIONS
  We developed a simple easy-to-use asthma control scoring system based on a percentage of optimal control. The percentage symptom score but not the global control score of this new method correlated with patient's global assessment of asthma control. This could be a simple tool that is potentially useful both for the clinician and for research purposes, to quantify global or specific aspects of asthma control.
authors.affiliation: Centre de recherche de l'Hôpital Laval, Institut de cardiologie et de pneumologie de l'Université Laval, 2725 chemin Sainte-Foy, Sainte-Foy, Québec, Canada. lpboulet@med.ulaval.ca
authors.forename: Louis-Philippe
authors.initials: LP
authors.lastname: Boulet
authors.forename: Véronique
authors.initials: V
authors.lastname: Boulet
authors.forename: Joanne
authors.initials: J
authors.lastname: Milot
mesh_terms: D001249:Asthma / Q000503:physiopathology / Q000628:therapy*; D004804:Eosinophils / Q000166:cytology; D005260:Female; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008297:Male; D011788:Quality of Life; D013183:Sputum / Q000166:cytology; D011795:Surveys and Questionnaires