title: Primary non-Hodgkin's lymphoma in Bartholin's gland.
abstract: BACKGROUND
  Non-Hodgkin's lymphoma (NHL) may involve the lower female genital tract, most often as a manifestation of systemic disease and rarely as a primarily localisation.
  
  
  METHODS
  A 73-year-old woman, HIV-negative, presented with a 5-month history of a mass in the left Bartholin's gland. The performed biopsy was reported to be a poorly differentiated carcinoma. Therefore, the patient underwent a vulvectomy with superficial groin node dissection. Unexpectedly, the definitive histological diagnosis showed that the tumor was an extranodal diffuse large B-cell non-Hodgkin lymphoma.
  
  
  CONCLUSIONS
  This is the first report of a NHL located in the Bartholin's gland. Primary NHLs involving the external genitalia are rare and often inaccurately diagnosed. A greater awareness of this entity among clinicians and pathologists could uncover more cases.
authors.affiliation: Division of Gynaecological Oncology, University Hospital Antwerp, Wilrijkstraat 10, 2650, Antwerp, Belgium. wiebren.tjalma@uza.be
authors.forename: Wiebren A A
authors.initials: WA
authors.lastname: Tjalma
authors.forename: Ann L R
authors.initials: AL
authors.lastname: Van de Velde
authors.forename: Wilfried A M
authors.initials: WA
authors.lastname: Schroyens
mesh_terms: D000368:Aged; D001472:Bartholin's Glands / Q000473:pathology*; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D014846:Vulvar Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy