Solitary esophageal metastasis of breast cancer after 11 years: a case report.
A patient with dysphagia and a history of breast cancer 11 yr ago was admitted to the hospital. A tumor presumably originating from the esophagus was detected. It could not be surgically removed and biopsy revealed adenocarcinoma. The patient received radiotherapy and chemotherapy consisting of etoposide, adriamycin, and cisplatin. An unexpectedly good response was achieved and the possibility of metastatic breast cancer was reinvestigated. Biopsy specimens showed positive estrogen and progesterone receptor staining. Tamoxifen treatment was started. The patient is well after 5 yr following relapse. Solitary esophageal metastasis of breast cancer is a rare event, especially after a remission period lasting more than a decade. Dysphagia in breast cancer patients should raise the suspicion of metastatic disease as well as esophageal cancer and benign strictures.
Erman
Mustafa
M
Department of Medical Oncology, Faculty of Medicine, Institute of Oncology, Hacettepe University, Sihhiye, Ankara, Turkey.
Karaoğlu
Aziz
A
Oksüzoğlu
Berna
B
Aydingöz
Ustün
U
Ayhan
Ayşe
A
Güler
Nilüfer
N
D000230:Adenocarcinoma / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000556:secondary* / Q000628:therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use; D003680:Deglutition Disorders / Q000209:etiology; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use; D004938:Esophageal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000556:secondary* / Q000628:therapy; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011859:Radiography; D011960:Receptors, Estrogen / Q000378:metabolism; D011980:Receptors, Progesterone / Q000378:metabolism; D013629:Tamoxifen / Q000627:therapeutic use*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D013629:Tamoxifen; D005047:Etoposide; D004317:Doxorubicin; D002945:Cisplatin