title: Comparison of percutaneous transmitral commissurotomy with Inoue balloon technique and metallic commissurotomy: immediate and short-term follow-up results of a randomized study.
abstract: BACKGROUND
  The Inoue balloon technique for mitral commissurotomy is well established and carried out worldwide. Metallic commissurotomy is reported to be a cheaper and effective alternative to balloon mitral commissurotomy.
  
  
  METHODS
  One hundred patients were randomized into 2 groups to undergo percutaneous transmitral commissurotomy (PTMC) by means of the Inoue balloon technique (IBMC, n = 49) or metallic commissurotomy (PMMC, n = 51). Patients were crossed over to the other technique when the initial technique was a failure. Success of valvotomy, procedure-related complications, and follow-up events of the 2 techniques were compared.
  
  
  RESULTS
  Basal echocardiographic and hemodynamic data were similar in both groups. Procedural success was similar in both groups: 45 of 49 procedures (91.8%) in the IBMC group, compared with 46 of 51 procedures (90.18%) in the PMMC group (P = 1.0). Crossover was also comparable, with 1 occurring in the IBMC group, compared with 3 in the PMMC group. Complications such as cardiac tamponade and mitral regurgitation (requiring or not requiring mitral valve replacement) were similar in both groups, with 3 complications in the IBMC group, compared with 4 complications in the PMMC group (P =.29). After a follow-up period of approximately 4 months, both groups had similar event rates and comparable hemodynamic parameters (P = not significant).
  
  
  CONCLUSIONS
  Both IBMC and PMMC are successful means of providing relief from severe mitral stenosis with a gain in valve area and reduction in transmitral gradient. Both techniques have similar procedural success, complication rates, and follow-up events.
authors.affiliation: Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
authors.forename: Anil
authors.initials: A
authors.lastname: Bhat
authors.forename: S
authors.initials: S
authors.lastname: Harikrishnan
authors.forename: J M
authors.initials: JM
authors.lastname: Tharakan
authors.forename: T
authors.initials: T
authors.lastname: Titus
authors.forename: V K Ajit
authors.initials: VK
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Sivasankaran
authors.forename: Francis
authors.initials: F
authors.lastname: Bimal
authors.forename: K M
authors.initials: KM
authors.lastname: Krishnamoorthy
mesh_terms: D000328:Adult; D021721:Balloon Occlusion; D006328:Cardiac Catheterization / Q000295:instrumentation / Q000379:methods*; D002404:Catheterization / Q000295:instrumentation / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000628:therapy*; D006801:Humans; D008297:Male; D008943:Mitral Valve