title: Phototherapy and systemic treatments.
abstract: A proportion of children and adults with moderate to severe atopic eczema are not adequately controlled with emollients and topical steroids, resulting in significant morbidity and disability. Studies indicate a significant placebo response, so randomized controlled trials of new treatments are vital. This article reviews the evidence for phototherapy and systemic treatments in atopic eczema.
authors.affiliation: Department of Dermatology, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH. n.j.reynolds@ncl.ac.uk
authors.forename: Nick J
authors.initials: NJ
authors.lastname: Reynolds
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Meggitt
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D016572:Cyclosporine / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000628:therapy*; D003879:Dermatologic Agents / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D007231:Infant, Newborn; D007371:Interferon-gamma / Q000633:toxicity; D010789:Phototherapy / Q000379:methods*; D013256:Steroids / Q000627:therapeutic use; D016305:Thymopentin / Q000627:therapeutic use
chemical_list: D000276:Adjuvants, Immunologic; D003879:Dermatologic Agents; D004365:Drugs, Chinese Herbal; D007166:Immunosuppressive Agents; D013256:Steroids; D007371:Interferon-gamma; D016572:Cyclosporine; D016305:Thymopentin