[Hemolytic activity and toxigenicity of Vibrio cholerae of different serogroups].
Experimental data on the comparative evaluation of the hemolytic activity of ctx+ Hly- and ctx- Hly+ V. cholerae, serogroups O1 and O139, in the process of their cultivation in different nutrient media are presented. The capacity of ctx+ V. cholerae of both serogroups cultivated under the conditions of iron deficiency, for the production of hemolysin capable of lyzing sheep red blood cells was shown. Hemolysin produced by ctx- strains of V. cholerae was synthesized under any conditions. The study of hemolysin preparations obtained from ctx- and ctx+ strains of V. cholerae, serogroups O1 and O139, revealed that they were biologically and immunologically similar.
Men'shikova
E A
EA
Research Institute for Plague Control, Rostov-on-Don, Russia.
Podosinnikova
L S
LS
Mironova
A V
AV
Sal'nikova
O I
OI
D000818:Animals; D000833:Animals, Suckling; D002772:Cholera Toxin / Q000276:immunology / Q000378:metabolism*; D006224:Cricetinae; D003470:Culture Media; D004912:Erythrocytes / Q000276:immunology; D006460:Hemolysin Proteins / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D007501:Iron; D011817:Rabbits; D012756:Sheep; D014734:Vibrio cholerae / Q000378:metabolism* / Q000472:pathogenicity
D003470:Culture Media; D006460:Hemolysin Proteins; D002772:Cholera Toxin; D007501:Iron