title: [Correlation between prenatal ultrasound diagnosis and findings from autopsies or neonatal operations due to structural congenital heart defects; a retrospective analysis].
abstract: OBJECTIVE
  To determine the contribution of the prenatal ultrasound diagnosis of structural congenital heart defects to the care of patients requiring surgery for their condition in the neonatal period.
  
  
  METHODS
  Retrospective.
  
  
  METHODS
  During the period January 1991-June 1999, data were collected from two groups of children. One group had a structural heart defect diagnosed prenatally and the other underwent a neonatal operation due to a heart defect. In the prenatal group, the management and follow-up were analysed, whilst in the surgery group, the extent to which ultrasound investigation had been performed and whether there was a relationship between prenatal diagnosis and the severity of acidosis were analysed.
  
  
  RESULTS
  A structural heart defect was found through prenatal ultrasound in 170 children and 64% of these prenatally diagnosed patients died before or immediately after birth, or the pregnancy was aborted. 14% underwent surgery within 31 days post partum. This last category formed an overlap with the surgery group. The surgery group contained 191 patients, who required surgery in the neonatal period, including 24 from the prenatal group. In total, 87% had no prenatal diagnosis. In the group with a prenatal diagnosis pre-operative lactate values were significantly lower.
  
  
  CONCLUSIONS
  The heart defect was only diagnosed prenatally in 13% of the patients from the surgery group, although this would have been technically feasible in 46%. Better prenatal diagnosis of heart disease could contribute to a better counselling of parents in their choice between abortion, conservative treatment or emergency surgery. In the case of emergency surgery, prenatal detection might lead to a decrease in morbidity and mortality.
authors.affiliation: Universitair Medisch Centrum Utrecht, afd. Kinderhartcentrum, Postbus 85.090, 3508 AB Utrecht.
authors.forename: P M
authors.initials: PM
authors.lastname: Verheijen
authors.forename: M M
authors.initials: MM
authors.lastname: Michon
authors.forename: L A
authors.initials: LA
authors.lastname: Lisowski
authors.forename: M A
authors.initials: MA
authors.lastname: Oudijk
authors.forename: P
authors.initials: P
authors.lastname: Stoutenbeek
authors.forename: E J
authors.initials: EJ
authors.lastname: Meijboom
mesh_terms: D000140:Acidosis, Lactic / Q000517:prevention & control; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000196:embryology / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D007773:Lactates / Q000097:blood; D011247:Pregnancy; D011248:Pregnancy Complications / Q000517:prevention & control; D011296:Prenatal Diagnosis; D011379:Prognosis; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal
chemical_list: D007773:Lactates