Trisomy 15 in a case of pediatric hemangiopericytoma and review of the literature.
This study reports on a pediatric case of hemangiopericytoma (HPC) showing trisomy 15 as a sole anomaly. Trisomy 15 was observed in a total of 11 cells harvested at a very early passage from two different in-situ cultures. Trisomy 15, as a sole anomaly, has been described in hematologic disorders such as myelodysplastic syndromes but, to our knowledge, has never been documented in solid tumors. This is the first report of HPC with trisomy 15.
Vadlamani
Indira
I
Department of Pathology, St. Louis University School of Medicine, St. Louis, MO, USA.
Ma
En
E
Brink
David S
DS
Batanian
Jacqueline R
JR
D002884:Chromosomes, Human, Pair 15 / Q000235:genetics*; D006393:Hemangiopericytoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D014314:Trisomy / Q000235:genetics*