Apatite-forming ability and mechanical properties of CaO-free poly(tetramethylene oxide) (PTMO)-TiO2 hybrids treated with hot water.
Poly(tetramethylene oxide) (PTMO)-TiO(2) hybrids were prepared by a sol-gel method from triethoxysilane-functionalized PTMO (Si-PTMO) and tetraisopropyltitanate with weight ratios of 30/70, 40/60 and 50/50 (hybrids PT30, PT40 and PT50, respectively), and subsequently subjected to a hot-water treatment at 95 degrees C for 2 d. All the obtained hybrids were amorphous before the hot-water treatment, and precipitated nanosized anatase after the hot-water treatment. The amount of precipitated anatase increased with decreasing PTMO content. Apatite was not formed on the surfaces of the hybrids in a simulated body fluid before the hot-water treatment, but was formed after the hot-water treatment, and its amount increased with decreasing PTMO content. Hybrid PT40 showed strength and Young's modulus analogous to those of human cancellous bones, and high ductility after the hot-water treatment. This kind of hybrid is expected to be useful as a new type of bone-repairing material.
Kamitakahara
Masanobu
M
Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. kamitakahara@sung7.kuic.kyoto-u.ac.jp
Kawashita
Masakazu
M
Miyata
Noboru
N
Kokubo
Tadashi
T
Nakamura
Takashi
T
D001031:Apatites / Q000378:metabolism*; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D018786:Bone Substitutes; D002516:Ceramics; D011232:Chemical Precipitation; D006358:Hot Temperature; D006801:Humans; D066298:In Vitro Techniques; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010087:Oxides; D014025:Titanium; D014867:Water
D001031:Apatites; D001672:Biocompatible Materials; D018786:Bone Substitutes; D010087:Oxides; C404813:polytetramethyloxide; D014867:Water; C009495:titanium dioxide; D014025:Titanium