Dynamics of Ly49 expressing cytotoxic lymphocyte subsets in response to virus infection.
Viral infections induce first a loss and then an increase in natural killer (NK) and CD8(+) T cells. NK cells expressing Ly49G2 were selectively expanded by several viruses and poly I:C. CD8(+) T cells expressing Ly49G2 were selectively expanded by poly I:C and participated in the antigen-specific response to lymphocytic choriomeningitis virus.
Peacock
Craig D
CD
Department of Pathology, University of Massachusetts Medical Center, 55 Lake Avenue North, Worcester, MA 01655, USA.
Xu
Weixin
W
Stepp
Susan E
SE
Welsh
Raymond M
RM
D000818:Animals; D000950:Antigens, Ly / Q000378:metabolism*; D005786:Gene Expression Regulation; D007694:Killer Cells, Natural / Q000276:immunology* / Q000378:metabolism*; D037181:Lectins, C-Type; D008217:Lymphocytic choriomeningitis virus / Q000276:immunology; D055630:Receptors, NK Cell Lectin-Like; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology* / Q000378:metabolism*; D014777:Virus Diseases / Q000276:immunology*
D000950:Antigens, Ly; D037181:Lectins, C-Type; D055630:Receptors, NK Cell Lectin-Like