Vertebrate development: taming the nodal waves.
Recent results have provided evidence that regulatory loops operating in vertebrate embryos between the developmental signalling factors Nodal and Lefty may provide a real example of the kind of reaction-diffusion process long predicted to be a mechanism of pattern formation.
Solnica-Krezel
Lilianna
L
Department of Biological Sciences, Vanderbilt University, VU Station B 351634, 37235-1634, Nashville, TN, USA. lilianna.solnica-krezel@vanderbilt.edu
D000818:Animals; D019521:Body Patterning / Q000502:physiology*; D004625:Embryo, Nonmammalian; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D055458:Left-Right Determination Factors; D008648:Mesoderm / Q000502:physiology; D055457:Nodal Protein; D016212:Transforming Growth Factor beta / Q000235:genetics / Q000378:metabolism*; D014714:Vertebrates / Q000196:embryology* / Q000235:genetics; D015027:Zebrafish / Q000196:embryology / Q000235:genetics
D055458:Left-Right Determination Factors; D055457:Nodal Protein; D016212:Transforming Growth Factor beta