title: Medical termination of missed abortion.
abstract: Missed abortions are a common occurrence and represent a heavy gynaecological emergency workload to both medical and nursing staff. The conventional method using vacuum aspiration of uterus is associated with morbidity and mortality. Medical termination of pregnancy is accepted as a safe and effective alternative method. However, medical evacuation of uterus in missed abortions had not been fully investigated. In this study we hope to examine the efficacy of medical methods for terminating missed abortions. Mifepristone and misoprostol prescribed to 100 women with an ultrasonically confirmed missed abortion was compared with 100 women who had surgical evacuation under general anaesthesia for their missed abortion. The disparity in complications between medical and surgical groups was not significantly different (Student's t-test, P=0.5). This study showed medical evacuation of missed abortion to be an effective, safe and cost-effective, alternative to surgical evacuation of the uterus and is particularly suited to women not wanting hospital admission or a surgical procedure under general anaesthesia. It represents an option of management that can be less intrusive and gives the woman some control but is both safe and effective.
authors.affiliation: Royal Bolton Hospital, Minerva Road, Farnworth, Bolton BL4 0JR, UK.
authors.forename: K V
authors.initials: KV
authors.lastname: Chia
authors.forename: V I
authors.initials: VI
authors.lastname: Ogbo
mesh_terms: D000019:Abortifacient Agents / Q000008:administration & dosage*; D000030:Abortion, Missed / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery; D000032:Abortion, Therapeutic / Q000379:methods*; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D015735:Mifepristone / Q000008:administration & dosage*; D016595:Misoprostol / Q000008:administration & dosage*; D010342:Patient Acceptance of Health Care; D011247:Pregnancy; D016896:Treatment Outcome; D014463:Ultrasonography; D014619:Vacuum Curettage
chemical_list: D000019:Abortifacient Agents; D016595:Misoprostol; D015735:Mifepristone