title: WormBase: a cross-species database for comparative genomics.
abstract: WormBase (http://www.wormbase.org/) is a web-accessible central data repository for information about Caenorhabditis elegans and related nematodes. The past two years have seen a significant expansion in the biological scope of WormBase, including the integration of large-scale, genome-wide data sets, the inclusion of genome sequence and gene predictions from related species and active literature curation. This expansion of data has also driven the development and refinement of user interfaces and operability, including a new Genome Browser, new searches and facilities for data access and the inclusion of extensive documentation. These advances have expanded WormBase beyond the obvious target audience of C. elegans researchers, to include researchers wishing to explore problems in functional and comparative genomics within the context of a powerful genetic system.
authors.affiliation: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
authors.forename: Todd W
authors.initials: TW
authors.lastname: Harris
authors.forename: Raymond
authors.initials: R
authors.lastname: Lee
authors.forename: Erich
authors.initials: E
authors.lastname: Schwarz
authors.forename: Keith
authors.initials: K
authors.lastname: Bradnam
authors.forename: Daniel
authors.initials: D
authors.lastname: Lawson
authors.forename: Wen
authors.initials: W
authors.lastname: Chen
authors.forename: Darin
authors.initials: D
authors.lastname: Blasier
authors.forename: Eimear
authors.initials: E
authors.lastname: Kenny
authors.forename: Fiona
authors.initials: F
authors.lastname: Cunningham
authors.forename: Ranjana
authors.initials: R
authors.lastname: Kishore
authors.forename: Juancarlos
authors.initials: J
authors.lastname: Chan
authors.forename: Hans-Michael
authors.initials: HM
authors.lastname: Muller
authors.forename: Andrei
authors.initials: A
authors.lastname: Petcherski
authors.forename: Gudmundur
authors.initials: G
authors.lastname: Thorisson
authors.forename: Allen
authors.initials: A
authors.lastname: Day
authors.forename: Tamberlyn
authors.initials: T
authors.lastname: Bieri
authors.forename: Anthony
authors.initials: A
authors.lastname: Rogers
authors.forename: Chao-Kung
authors.initials: CK
authors.lastname: Chen
authors.forename: John
authors.initials: J
authors.lastname: Spieth
authors.forename: Paul
authors.initials: P
authors.lastname: Sternberg
authors.forename: Richard
authors.initials: R
authors.lastname: Durbin
authors.forename: Lincoln D
authors.initials: LD
authors.lastname: Stein
mesh_terms: D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000196:embryology / Q000235:genetics* / Q000254:growth & development; D018509:DNA, Helminth / Q000032:analysis; D003625:Data Collection; D030561:Databases, Nucleic Acid; D020224:Expressed Sequence Tags; D015870:Gene Expression; D023281:Genomics; D016247:Information Storage and Retrieval; D009474:Neurons / Q000145:classification; D020641:Polymorphism, Single Nucleotide; D011786:Quality Control; D034622:RNA Interference; D018510:RNA, Helminth / Q000037:antagonists & inhibitors; D012689:Sequence Homology, Nucleic Acid
chemical_list: D018509:DNA, Helminth; D018510:RNA, Helminth