Non-obese hyperlipidemic Asian northern Indian males have adverse anthropometric profile.
OBJECTIVE
Hyperlipidemia is commonly ascribed to obesity. We studied the association of anthropometric profile and nutrient intake with hyperlipidemia in non-obese Asian Indian males.


RESULTS
In a case-control study, non-diabetic, non-obese males with body mass index (BMI) < 25 Kg/m2 having primary hyperlipidemia (n = 50) were compared with healthy normolipidemic males (BMI < 25 Kg/m2, n = 50). In this study, BMI (p < 0.001), waist circumference (WC) (p < 0.001), waist/hip ratio (p < 0.01), skinfolds (p < 0.001), sum of four skinfolds (p < 0.001), and percentage of body fat (%BF) (p < 0.001) were significantly higher in hyperlipidemic subjects as compared to normolipidemic controls. High %BF (> 25%) was observed in 26% of hyperlipidemic subjects and in 8% normolipidemic controls (p < 0.01). Using analysis of covariance (after adjusting for BMI), WC (p < 0.001), %BF (p < 0.01) and %BF/BMI ratio (p < 0.01) were significantly higher in the hyperlipidemic subjects. Intakes of total calories, total fat, saturated fat, carbohydrates, n-3 and n-6 fatty acids, dietary fiber, vitamin E and n-6/n-3 fatty acids ratio were statistically comparable between the two groups. In hyperlipidemic subjects biceps skinfold correlated negatively to levels of high-density lipoprotein cholesterol (r = -0.28, p < 0.05) and serum triglycerides correlated positively to intakes of carbohydrate (r = 0.31, p < 0.05), and dietary n-3 fatty acids (r = 0.34, p < 0.05).


CONCLUSIONS
Hyperlipidemic Asian Indian males, defined as "non-obese" based on BMI, had adverse profile of anthropometric parameters and excess %BF as compared to normolipidemic males. Therefore, while dealing with hyperlipidemic Asian Indians, physicians should consider anthropometric parameters (WC), %BF, and %BF/BMI ratio in addition to BMI in the clinical assessment.
Misra
A
A
Department of Medicine, All India Institute of Medical Sciences, New Delhi, India. anoopmisra@hotmail.com
Athiko
D
D
Sharma
R
R
Pandey
R M
RM
Khanna
N
N
D000273:Adipose Tissue / Q000033:anatomy & histology*; D000328:Adult; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis; D001823:Body Composition / Q000502:physiology*; D001824:Body Constitution / Q000502:physiology*; D015992:Body Mass Index; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D004032:Diet; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000503:physiopathology*; D007194:India; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood; D012885:Skinfold Thickness; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D014280:Triglycerides; D002784:Cholesterol