Citrated blood does not reliably reflect fresh whole blood coagulability in trials of in vitro hemodilution.
Citration and storage of whole blood markedly alter the Thrombelastograph effects of hemodilution on coagulation. The results of hemodilution studies in which citrated blood has been used to study coagulation may not be reliable.
Roche
A M
AM
Centre for Anaesthesia, University College London, Middlesex Hospital, United Kingdom.
James
M F M
MF
Grocott
M P W
MP
Mythen
M G
MG
D001777:Blood Coagulation / Q000187:drug effects*; D001793:Blood Preservation; D002951:Citrates / Q000494:pharmacology*; D006438:Hemodilution; D006801:Humans; D066298:In Vitro Techniques; D013916:Thrombelastography
D002951:Citrates