title: Minimal tissue damage after stimulation of the motor thalamus in a case of chorea-acanthocytosis.
abstract: Autopsy findings are reported from a patient with chorea-acanthocytosis treated for 2 years by deep brain stimulation (DBS) of the motor thalamus. Postoperative testing showed a progressive improvement in axial truncal spasms. Although relatively high currents were used for 2 years in this patient, postmortem analysis showed minimal tissue damage in the vicinity of the electrode tip. It is concluded that DBS has little impact on the surrounding tissues.
authors.affiliation: Department of Clinical Neurophysiology, Hôpital Pellegrin, Bordeaux, France. Pierre.Burbaud@umr5543.u-bordeaux2.fr
authors.forename: P
authors.initials: P
authors.lastname: Burbaud
authors.forename: A
authors.initials: A
authors.lastname: Vital
authors.forename: A
authors.initials: A
authors.lastname: Rougier
authors.forename: S
authors.initials: S
authors.lastname: Bouillot
authors.forename: D
authors.initials: D
authors.lastname: Guehl
authors.forename: E
authors.initials: E
authors.lastname: Cuny
authors.forename: X
authors.initials: X
authors.lastname: Ferrer
authors.forename: A
authors.initials: A
authors.lastname: Lagueny
authors.forename: B
authors.initials: B
authors.lastname: Bioulac
mesh_terms: D000328:Adult; D001344:Autopsy; D002819:Chorea / Q000150:complications / Q000473:pathology* / Q000628:therapy*; D004599:Electric Stimulation Therapy / Q000009:adverse effects*; D004567:Electrodes, Implanted / Q000009:adverse effects; D006801:Humans; D008297:Male; D011859:Radiography; D013035:Spasm / Q000209:etiology / Q000628:therapy; D013788:Thalamus / Q000000981:diagnostic imaging / Q000473:pathology* / Q000502:physiology*