title: Delayed onset of malignant hyperthermia in desflurane anesthesia.
abstract: Animal-experimental studies demonstrate desflurane's trigger effect for malignant hyperthermia (MH). In contrast to other anesthetics, the time interval from exposure to the occurrence of symptoms is much longer with desflurane. This case report focuses on MH induced by desflurane alone.
authors.affiliation: Department of Anesthesiology and Critical CareUniversitätsklinikum Münster, Germany. hoenemann@anit.uni-muester.de
authors.forename: Christian W
authors.initials: CW
authors.lastname: Hoenemann
authors.forename: Tobias B
authors.initials: TB
authors.lastname: Halene-Holtgraeve
authors.forename: Michael
authors.initials: M
authors.lastname: Booke
authors.forename: Frank
authors.initials: F
authors.lastname: Hinder
authors.forename: Fritz
authors.initials: F
authors.lastname: Daudel
authors.forename: Alexander
authors.initials: A
authors.lastname: Reich
authors.forename: Hugo
authors.initials: H
authors.lastname: Van Aken
mesh_terms: D000293:Adolescent; D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D001706:Biopsy; D003620:Dantrolene / Q000627:therapeutic use; D000077335:Desflurane; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D007530:Isoflurane / Q000009:adverse effects* / Q000031:analogs & derivatives*; D008305:Malignant Hyperthermia / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D016343:Monitoring, Intraoperative; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D018482:Muscle, Skeletal / Q000187:drug effects; D019637:Orthopedic Procedures; D011184:Postoperative Period; D012600:Scoliosis / Q000601:surgery
chemical_list: D018685:Anesthetics, Inhalation; D009125:Muscle Relaxants, Central; D000077335:Desflurane; D007530:Isoflurane; D003620:Dantrolene