title: DNA repair: bacteria join in.
abstract: In higher organisms, a major pathway for repairing double stranded breaks in DNA is non-homologous end-joining. Now a similar pathway has been shown to operate in bacterial cells, indicating that this important repair mechanism has been conserved through evolution.
authors.affiliation: MRC Laboratory of Molecular Biology, Hills Road, CB2 2QH, Cambridge, UK. hiom@mrc-lmb.cam.ac.uk
authors.forename: Kevin
authors.initials: K
authors.lastname: Hiom
mesh_terms: D000818:Animals; D034961:Antigens, Nuclear / Q000502:physiology; D001419:Bacteria / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D004265:DNA Helicases; D000072481:DNA Ligase ATP; D011088:DNA Ligases / Q000235:genetics / Q000378:metabolism; D004260:DNA Repair / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000502:physiology; D000072200:Ku Autoantigen; D008322:Mammals / Q000235:genetics
chemical_list: D034961:Antigens, Nuclear; D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D004265:DNA Helicases; C106893:XRCC5 protein, human; C000606509:Xrcc6 protein, human; D000072200:Ku Autoantigen; D011088:DNA Ligases; D000072481:DNA Ligase ATP