Histone modifications: an assembly line for active chromatin?
Histone modifications play a major role in the control of genes in their natural chromatin context. A detailed, time-resolved analysis of histone modifications during gene activation has now revealed the order of appearance of particular histone modifications on a promoter during regulatory processes.
Imhof
Axel
A
Adolf-Butenandt Institut, Ludwig Maximillians University of Munich, Schillerstr. 44, 80336, München, Germany. imhof@mol-bio.med.uni-muenchen.de
D000818:Animals; D002843:Chromatin / Q000235:genetics / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008745:Methylation; D011401:Promoter Regions, Genetic; D011484:Protein-Arginine N-Methyltransferases / Q000235:genetics / Q000378:metabolism*; D015533:Transcriptional Activation / Q000502:physiology
D002843:Chromatin; D006657:Histones; D011484:Protein-Arginine N-Methyltransferases; C119966:coactivator-associated arginine methyltransferase 1