Nasal polyposis in children with cystic fibrosis: a long-term follow-up study.
The incidence of nasal polyposis among children 5 to 18 years of age with cystic fibrosis (CF) was investigated with a systematic examination of all children on the local CF register. Out of 23 children with CF, 13 had endoscopic evidence of nasal polyposis. Four children had grade 2 polyposis, and 9 children had grade 3 polyposis. Complete opacity of the maxillary sinus was identified on a computed tomographic sinus scan in all but 2 of the children. Only 1 child had a developed frontal sinus. Between 1989 and 2000, 12 children underwent radical endoscopic sinus surgery for their nasal polyposis. There was good postoperative improvement in all of the children; however, 7 eventually required revision surgery because of recurrence of the nasal polyps. The median interval between repeated sinus surgeries was 4 years (range, 18 months to more than 6 years). This information can help in the counseling of parents when sinus surgery is considered for children with CF.
Yung
Matthew W
MW
Department of Otolaryngology-Head and Neck Surgery, The Ipswich Hospital NHS Trust, Ipswich, England, United Kingdom.
Gould
Jim
J
Upton
Graham J G
GJ
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications* / Q000235:genetics; D004724:Endoscopy; D004739:England / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009298:Nasal Polyps / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D010353:Patient Education as Topic; D012008:Recurrence; D012042:Registries; D012086:Reoperation; D012220:Rhinitis / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D012720:Severity of Illness Index; D012852:Sinusitis / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome