Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia.
Tortiglione
A
A
Division of Pharmacology, Department of Neuroscience, School of Medicine, Federico II University of Naples, 80131 Naples, Italy.
Pignataro
G
G
Minale
M
M
Secondo
A
A
Scorziello
A
A
Di Renzo
G F
GF
Amoroso
S
S
Caliendo
G
G
Santagada
V
V
Annunziato
L
L
D000255:Adenosine Triphosphate / Q000378:metabolism; D000595:Amino Acid Sequence; D015764:Bepridil / Q000494:pharmacology; D001692:Biological Transport / Q000187:drug effects; D002545:Brain Ischemia / Q000503:physiopathology*; D002118:Calcium / Q000378:metabolism*; D003847:Deoxyglucose / Q000494:pharmacology; D005910:Glioma; D006019:Glycolysis / Q000187:drug effects; D006031:Glycosylation; D006801:Humans; D002534:Hypoxia, Brain / Q000503:physiopathology*; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008959:Models, Neurological; D008969:Molecular Sequence Data; D018696:Neuroprotective Agents; D009840:Oligomycins / Q000494:pharmacology*; D010455:Peptides / Q000494:pharmacology; D010766:Phosphorylation; D012964:Sodium / Q000378:metabolism*; D019831:Sodium-Calcium Exchanger / Q000737:chemistry / Q000502:physiology*; D014407:Tumor Cells, Cultured
D018696:Neuroprotective Agents; D009840:Oligomycins; D010455:Peptides; D019831:Sodium-Calcium Exchanger; C066745:exchanger inhibitory peptide; D015764:Bepridil; D000255:Adenosine Triphosphate; D003847:Deoxyglucose; D012964:Sodium; D007770:L-Lactate Dehydrogenase; D002118:Calcium