[Deafness and aging: studies in experimental models].
Since 1970 a progressive aging of the world population, mainly in the most developed countries, has been observed. Spain could have, around 2050, the most aged human population of the world. Therefore, scientist show an increasing interest on the study of the aging-related pathologies (i.e. deafness linked to aging process: presbycusis). The deep analysis of the presbycusis physiopathology will be based on the study of patients, but also on animal models. This report summarizes our results obtained on the analysis of the deafness linked to aging on the C57/BL/6 mice.
Gil Loyzaga
Pablo E
PE
D000368:Aged; D000375:Aging / Q000473:pathology*; D000818:Animals; D003638:Deafness / Q000209:etiology*; D004195:Disease Models, Animal; D018698:Glutamic Acid / Q000378:metabolism; D006311:Hearing Disorders / Q000209:etiology / Q000503:physiopathology; D006319:Hearing Loss, Sensorineural / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D008954:Models, Biological; D009622:Noise / Q000009:adverse effects; D009925:Organ of Corti / Q000503:physiopathology / Q000648:ultrastructure; D011304:Presbycusis / Q000209:etiology / Q000503:physiopathology; D013030:Spain
D018698:Glutamic Acid