ELF fields and photooxidation yielding lethal effects on cancer cells.
The lethal effect on human cancer cells was studied under three types of treatment: A) an ELF pulsed sinusoidal of 50 Hz electromagnetic field (PEMF) with amplitudes between 10 and 55 mT; B) the field and a cytostatic agent (actinomycin-C); and C) the field, the cytostatic agent, which has a photodynamic effect, and exposure to a halogen lamp. The results show a decreasing vitality of human K-562 and U-937 cancer cells in suspension with each additional treatment. Combination with other parameters as hyperthermia and/or hyperacidity could yield high killing rates by this noninvasive method.
Traitcheva
Nelly
N
Laboratory of Bioelectrochemistry, Institute of Virology, FSU, Jena, Germany.
Angelova
Plamena
P
Radeva
Maria
M
Berg
Hermann
H
D017209:Apoptosis / Q000187:drug effects / Q000528:radiation effects; D003609:Dactinomycin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D004574:Electromagnetic Fields; D006801:Humans; D020014:K562 Cells / Q000187:drug effects* / Q000528:radiation effects*; D008027:Light; D010778:Photochemotherapy / Q000379:methods; D020298:U937 Cells / Q000187:drug effects* / Q000528:radiation effects*
C030013:cactinomycin; D003609:Dactinomycin