title: [40-year-old man with primary antiphospholipid syndrome].
abstract: We report the case o a 40-year-old male patient with "primary antiphospholipid syndrome" who developed ischemic cerebral infarctions and renal microangiopathy with infarction. A review of the literature on renal involvement in the primary antiphospholipid syndrome disclosed the differences from the antiphospholipid syndrome in the systemic lupus erythematosus. We describe the evolution of the patient at eight years, and we emphasize the importance of the treatment with warfarin. Also, we review the pathophysiology of severe secondary arterial hypertension.
authors.affiliation: Unidad de Nefrología, Corporación Parc Taulí, 08208 Sabadell, Barcelona.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez Jornet
authors.forename: F J
authors.initials: FJ
authors.lastname: Andreu
authors.forename: C
authors.initials: C
authors.lastname: Tolosa
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000188:drug therapy; D001160:Arterioles / Q000473:pathology; D002545:Brain Ischemia / Q000209:etiology*; D002544:Cerebral Infarction / Q000209:etiology*; D004401:Dysarthria / Q000209:etiology; D005355:Fibrosis; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology; D007238:Infarction / Q000209:etiology*; D007668:Kidney / Q000098:blood supply*; D008279:Magnetic Resonance Imaging; D008297:Male; D012907:Smoking / Q000009:adverse effects; D019851:Thrombophilia / Q000188:drug therapy / Q000209:etiology; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin