New scalarane class sesterterpenes from an Indonesian sponge, Phyllospongia sp.
A series of scalarane class sesterterpenes (1-8) have been isolated from an Indonesian sponge, Phyllospongia sp. Their structures were determined by spectroscopic analysis and confirmed by single-crystal X-ray diffraction on compound 1. The absolute stereochemistry of 1 was established by modified Mosher's method.
Roy
Michael C
MC
Department of Chemistry, Biology, and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan.
Tanaka
Junichi
J
de Voogd
Nicole
N
Higa
Tatsuo
T
D000818:Animals; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007214:Indonesia; D007624:KB Cells / Q000187:drug effects; D008745:Methylation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*; D054830:Sesterterpenes; D017550:Spectroscopy, Fourier Transform Infrared; D013237:Stereoisomerism; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014961:X-Ray Diffraction
D054830:Sesterterpenes; D013729:Terpenes