title: Pancreatic metastasis and extrahepatic biliary obstruction in squamous cell lung carcinoma.
abstract: Primary lung cancer frequently metastasizes to distant organs. The pancreas is a relatively infrequent site of metastasis. As a result, extrahepatic bile duct obstruction (EHBDO) resulting from pancreatic metastasis from lung cancer is extremely rare and occurs mostly with small-cell lung cancer (SCLC). We report an unusual case in which a patient presented with jaundice and, after extensive workup, was diagnosed with squamous cell carcinoma of the lung with metastasis to the pancreas causing EHBDO. He underwent endoscopic retrograde cholangiopancreatography (ERCP) and the obstruction was relieved with a stent placement. The patient was treated with combination chemotherapy (carboplatin and paclitaxel) with a good clinical and radiographic response.
authors.affiliation: Department of Internal Medicine, University of North Dakota School of Medicine, Meritcare Health System, 720 North 4 Street, Fargo, ND 58122, USA. naumanmoazzam@meritcare.com
authors.forename: Nauman
authors.initials: N
authors.lastname: Moazzam
authors.forename: Ali
authors.initials: A
authors.lastname: Mir
authors.forename: Anil
authors.initials: A
authors.lastname: Potti
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000556:secondary*; D001651:Cholestasis, Extrahepatic / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000556:secondary*