Influence of diet on the shedding of Candida glabrata by experimentally infected preweaned calves.
The influence of three diets, comprising dam's milk (DM) from the same farm, commercial milk replacer with (CMRL) or without 3.2% lactose (CMR), on the duration and intensity of Candida glabrata shedding in the faeces of preweaned calves following experimental oral infection was examined. Shedding of other potential enteric pathogens was also monitored. The duration and intensity of C. glabrata shedding in DM-fed calves were reduced significantly compared with the calves fed the two diets based on milk replacers. Consequently, feeding calves with DM might disrupt the infective cycle, resulting in the yeast's elimination from a farm. In the CMR and CMRL groups, the periods of intensive shedding of C. glabrata and rotavirus overlapped but no diarrhoea was associated with the shedding of either microorganism. There was no evidence that lactose diminished colonization in vivo.
Elad
D
D
Department of Clinical Bateriology and Mycology, The Kimron Veterinary Institute, PO Box 12, Bet Dagan, 50250 Israel. elad@agri.huji.ac.il
Brenner
J
J
Markovitcs
A
A
Shlomovitz
S
S
Basan
J
J
Schwartz
N
N
D000818:Animals; D000833:Animals, Suckling; D041221:Candida glabrata / Q000302:isolation & purification / Q000502:physiology*; D002177:Candidiasis / Q000178:diet therapy / Q000276:immunology / Q000382:microbiology* / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000178:diet therapy / Q000276:immunology / Q000382:microbiology*; D004032:Diet; D005243:Feces / Q000382:microbiology; D007136:Immunoglobulins / Q000097:blood; D007785:Lactose / Q000032:analysis; D008892:Milk / Q000737:chemistry; D012401:Rotavirus / Q000302:isolation & purification
D007136:Immunoglobulins; D007785:Lactose