title: [Comparative population study of the etiological role of causative agents of purulent inflammatory diseases and serum antibodies to antigens of opportunistic microorganisms].
abstract: The comparative study of the relationship between the levels of serum antibodies to the antigens of opportunistic microorganisms of 5 genera (Pseudomonas, Proteus, Staphylococcus, Klebsiella, Escherichia) and the microbial status was carried out. A total of 854 patients from 10 profile departments of a surgical hospital were examined. Population analysis and statistical methods of processing the results of the examination of 353 practically healthy subjects and 268 blood and plasma donors permitted the norms for the levels of specific antimicrobial antibodies (decreased, normal, elevated levels) were established. The constancy coefficients of Pseudomonas, Staphylococcus, Klebsiella, Escherichia and the number of patients with elevated titers of specific serum antibodies were found to be positively correlated (r = +0.47-0.89, p < 0.01). The data thus obtained made it possible to substantiate the importance of population serological investigations for the evaluation of the epidemiological situation in the surgical hospital.
authors.affiliation: Sklifosovsky Research Institute of Emergency Aid, Moscow, Russia.
authors.forename: V B
authors.initials: VB
authors.lastname: Khvatov
authors.forename: U U
authors.initials: UU
authors.lastname: Bitkova
authors.forename: R F
authors.initials: RF
authors.lastname: Astaf'eva
authors.forename: M V
authors.initials: MV
authors.lastname: Androsova
authors.forename: E D
authors.initials: ED
authors.lastname: Men'shikova
authors.forename: M A
authors.initials: MA
authors.lastname: Godkov
authors.forename: D D
authors.initials: DD
authors.lastname: Men'shikov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood*; D001424:Bacterial Infections / Q000382:microbiology; D001782:Blood Donors; D004925:Escherichia / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007709:Klebsiella / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000382:microbiology; D011159:Population Surveillance; D011511:Proteus / Q000302:isolation & purification*; D011549:Pseudomonas / Q000302:isolation & purification*; D012016:Reference Values; D012044:Regression Analysis; D013210:Staphylococcus / Q000302:isolation & purification*; D013503:Surgery Department, Hospital
chemical_list: D000907:Antibodies, Bacterial