title: [Treatment of hypercalcemia of malignancy with pamidronate in a patient with advanced recurrent oral cancer].
abstract: Hypercalcemia of malignancy is a common problem for cancer clinicians. Treatment of hypercalcemia of malignancy with pamidronate in a patient with advanced recurrent oral cancer is reported herein. The patient was a 36-year-old man who had neck lymph node metastases due to recurrence of squamous cell carcinoma of the buccal mucosa and complained of cloudiness of consciousness due to hypercalcemia. The patient was administered pamidronate. A fine reduction in serum calcium was observed and cloudiness of consciousness was also alleviated. Although treatment of hypercalcemia with pamidronate is palliative, it is effective against the deterioration of quality of life.
authors.affiliation: Dept. of Dentistry and Oral Surgery, Hyogo College of Medicine.
authors.forename: Norihiko
authors.initials: N
authors.lastname: Nishimura
authors.forename: Yuki
authors.initials: Y
authors.lastname: Matsushita
authors.forename: Kazuki
authors.initials: K
authors.lastname: Takaoka
authors.forename: Susumu
authors.initials: S
authors.lastname: Hashitani
authors.forename: Kazuma
authors.initials: K
authors.lastname: Noguchi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Urade
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary; D003244:Consciousness Disorders / Q000209:etiology; D004164:Diphosphonates / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy* / Q000209:etiology; D008207:Lymphatic Metastasis; D008297:Male; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000523:psychology; D000077268:Pamidronate; D011788:Quality of Life
chemical_list: D000970:Antineoplastic Agents; D004164:Diphosphonates; D000077268:Pamidronate