title: [Three cases of advanced and recurrent gastric cancer treated with paclitaxel after TS-1 administration].
abstract: The importance of chemotherapy in the treatment of gastric cancer has increased after the appearance of more effective new agents such as TS-1. Therefore, the development of second line chemotherapy following TS-1 administration is needed urgently. Recently, we treated three cases of advanced and recurrent gastric cancers, using paclitaxel after TS-1 treatment. We herein describe these cases and discuss the therapeutic effect of paclitaxel and drug-related side effects in these patients.
authors.affiliation: Dept. of Surgery and Clinical Oncology, Graduate School of Medicine, Osaka University.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Tamura
authors.forename: Setsuko
authors.initials: S
authors.lastname: Yoshioka
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Okada
authors.forename: Shuji
authors.initials: S
authors.lastname: Takiguchi
authors.forename: Masahiko
authors.initials: M
authors.lastname: Yano
authors.forename: Takushi
authors.initials: T
authors.lastname: Yasuda
authors.forename: Morito
authors.initials: M
authors.lastname: Monden
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage*; D011725:Pyridines / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy*; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D000964:Antimetabolites, Antineoplastic; D000972:Antineoplastic Agents, Phytogenic; D004338:Drug Combinations; D011725:Pyridines; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D017239:Paclitaxel