[The role of substantia nigra in the cognitive activity in cats].
The role of substantia nigra (SN) in the cat cognitive activity of different complexity degree, was investigated by original technique. Neurosurgery or neurochemical SN switching off leads to reliable disturbances of condition, reflexes, generalization and abstraction. Rehabilitation was possible after pharmacological stimulation of dopaminergic, partly GABA-ergic, and cholinergic systems. Stimulation of serotonin system was ineffective.
Mukhin
E I
EI
Brain Research Institute of the Russian Acad. Med. Sci., 105064, Moscow, 5, Per. Obukha, Russia.
Mukhina
Iu K
IuK
Nabieva
T N
TN
D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D002415:Cats; D003071:Cognition / Q000187:drug effects / Q000502:physiology*; D003216:Conditioning, Operant / Q000502:physiology; D005260:Female; D005702:Galantamine / Q000494:pharmacology; D020267:MPTP Poisoning; D008297:Male; D009118:Muscimol / Q000494:pharmacology; D011950:Receptors, Cholinergic / Q000502:physiology; D011954:Receptors, Dopamine / Q000502:physiology; D018079:Receptors, GABA / Q000502:physiology; D013378:Substantia Nigra / Q000187:drug effects / Q000502:physiology*
D011950:Receptors, Cholinergic; D011954:Receptors, Dopamine; D018079:Receptors, GABA; D005702:Galantamine; D009118:Muscimol; D006916:5-Hydroxytryptophan