title: Continuous Holter telemetry of atrial electrograms and marker annotations using a common Holter recording system: impact on Holter electrocardiogram interpretation in patients with dual chamber pacemakers.
abstract: The impact of continuous telemetry of atrial electrogram and marker annotations on Holter ECG interpretation was assessed in 98 patients with bipolar dual chamber pacemakers (VDD pacemakers n = 29, DDD(R) systems n = 69). Atrial electrogram and marker annotations were continuously sampled by a telemetry coil that was externally positioned on the pacemaker pocket, amplified, and transduced to a three-channel Holter ECG recorder in addition to an ECG recording. Holter tapes were analyzed by two experienced investigators for quality of P wave recognition and episodes suspicious of pacemaker dysfunction. Initially, only the ECG channel was analyzed. Thereafter, results were compared to those achieved on the basis of the complete recording including atrial electrogram and marker annotations. Recognition of atrial rhythm was markedly improved by Holter telemetry. During 99.3% of recording time telemetry showed a satisfying quality, whereas ECG alone allowed a reliable P wave recognition only during 84.4% of recording time (P < 0.001). One hundred twenty-nine episodes suspicious of pacemaker malfunction occurred in 17 of 98 patients. By analysis of ECG, only 78.3% of episodes were concordantly classified by the investigators. However, 98.4% of all episodes were properly identified when atrial electrogram and marker annotations were added to the analysis (P < 0.001). In particular, discrimination between atrial undersensing, sinus bradycardia, and atrial sensed events within the refractory periods was facilitated. Holter telemetry of atrial electrogram and marker annotations facilitates the analysis of Holter ECGs in pacemaker recipients and improves the detection of pacemaker dysfunctions.
authors.affiliation: Department of Internal Medicine II, Medical University of Luebeck, Luebeck, Germany. uwe.wiegand@medinf.mu-luebeck.de
authors.forename: Uwe K H
authors.initials: UK
authors.lastname: Wiegand
authors.forename: Hendrik
authors.initials: H
authors.lastname: Bonnemeier
authors.forename: Frank
authors.initials: F
authors.lastname: Bode
authors.forename: Frank
authors.initials: F
authors.lastname: Eberhardt
authors.forename: Julian K R
authors.initials: JK
authors.lastname: Chun
authors.forename: Hugo A
authors.initials: HA
authors.lastname: Katus
authors.forename: Werner
authors.initials: W
authors.lastname: Peters
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory / Q000379:methods*; D004867:Equipment Design; D005260:Female; D006327:Heart Block / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008297:Male; D008904:Miniaturization; D010138:Pacemaker, Artificial; D015203:Reproducibility of Results; D012804:Sick Sinus Syndrome / Q000503:physiopathology / Q000628:therapy; D012815:Signal Processing, Computer-Assisted; D012984:Software; D013686:Telemetry / Q000295:instrumentation