[The coinfection of hepatitis C virus with hepatitis G virus and its reaction to interferon treatment].
HGV RNA was detected in 60 cases of hepatitis C patients and its positive rate was 23.3%, also the HGV infection was more frequent in chronic hepatitis C patients than in acute hepatitis C, and was only detected in hepatitis C patients who experienced transfusion of blood or blood products. These results indicated that transfusion was the main transmission route for HGV infection. HGV infection could shorten the incubation period of post-transfusion hepatitis C, but it would not worsen the status of the disease. The coinfection of HCV and HGV did not interfere the effect of interferon treatment on hepatitis C patients either in normalization of ALT or the elimination of HCV.
Wang
H
H
Institute of Hepatology of People's Hospital, Beijing Medical University, Beijing 100044.
Sun
Y
Y
Chang
J
J
D000328:Adult; D005260:Female; D018178:Flaviviridae Infections / Q000188:drug therapy*; D029407:GB virus C / Q000235:genetics / Q000302:isolation & purification; D006526:Hepatitis C / Q000188:drug therapy*; D006525:Hepatitis, Viral, Human / Q000188:drug therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood; D011994:Recombinant Proteins; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015163:Superinfection / Q000188:drug therapy
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D012367:RNA, Viral; D011994:Recombinant Proteins