Statistical evaluation and comparison of comet assay results.
A method of critical evaluation of comet assay test results is proposed. This method is based on representing frequency histograms of tail moments and %DNA in the tail with the use of the unsymmetrical Weibull distribution. The distribution is fully characterized by two parameters: shape (alpha) and scale (beta). Coefficients of variation and confidence intervals of the parameters have been determined.
Ejchart
Anna
A
Drug Institute, 30/34 Chelmska Street, 00-725 Warsaw, Poland.
Sadlej-Sosnowska
Nina
N
D001761:Bleomycin / Q000494:pharmacology; D002478:Cells, Cultured; D020552:Comet Assay / Q000379:methods*; D004249:DNA Damage / Q000187:drug effects; D003627:Data Interpretation, Statistical; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D016008:Statistical Distributions
D001761:Bleomycin