title: Changes in patterns of antimicrobial susceptibility and integron carriage among Shigella sonnei isolates from southwestern Korea during epidemic periods.
abstract: Shigella sonnei isolates from southwestern Korea during the epidemic periods of 1998 to 2000 were genetically related. The antimicrobial susceptibilities of the outbreak-related isolates changed annually. All isolates carried class 2 integrons, and the outbreak-related isolates from 1999 also carried class 1 integrons. The antimicrobial susceptibilities of S. sonnei isolates are readily changed by antibiotic selective pressures, and integrons are responsible for resistance to antimicrobial agents commonly used to treat shigellosis.
authors.affiliation: Department of Microbiology, College of Medicine, Seonam University, Namwon, ChunPook 590-711, Korea.
authors.forename: Jae Young
authors.initials: JY
authors.lastname: Oh
authors.forename: Hak Sun
authors.initials: HS
authors.lastname: Yu
authors.forename: Sung Ki
authors.initials: SK
authors.lastname: Kim
authors.forename: Seong Yong
authors.initials: SY
authors.lastname: Seol
authors.forename: Dong Taek
authors.initials: DT
authors.lastname: Cho
authors.forename: Je Chul
authors.initials: JC
authors.lastname: Lee
mesh_terms: D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004405:Dysentery, Bacillary / Q000453:epidemiology / Q000235:genetics / Q000382:microbiology*; D006801:Humans; D032023:Integrons / Q000502:physiology*; D007723:Korea / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D012764:Shigella sonnei / Q000187:drug effects* / Q000235:genetics