title: Carbon nanotube array-based biosensor.
abstract: Aligned multi-wall carbon nanotubes (MWNT) grown on platinum substrate are used for the development of an amperometric biosensor. The opening and functionalization by oxidation of the nanotube array allows for the efficient immobilization of the model enzyme, glucose oxidase. The carboxylated open-ends of nanotubes are used for the immobilization of the enzymes, while the platinum substrate provides the direct transduction platform for signal monitoring. It is also shown that carbon nanotubes can play a dual role, both as immobilization matrices and as mediators, allowing for the development of a third generation of biosensor systems, with good overall analytical characteristics.
authors.affiliation: Laboratory of Analytical Chemistry, Department of Chemistry, University of Crete, Iraklion 71 409 Crete, Greece.
authors.forename: Sofia
authors.initials: S
authors.lastname: Sotiropoulou
authors.forename: Nikolas A
authors.initials: NA
authors.lastname: Chaniotakis
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D002138:Calibration; D004867:Equipment Design; D037742:Nanotubes, Carbon
chemical_list: D037742:Nanotubes, Carbon