title: Chromatin silencing: RNA in the driving seat.
abstract: Recent studies have provided major new insights into the mechanism by which eukaryotic organisms initiate heterochromatin formation. Surprisingly, RNA appears to be a central component of the chromatin silencing machinery.
authors.affiliation: Department of Biology, University of Leicester, LE1 7RH, Leicester, UK.
authors.forename: David S
authors.initials: DS
authors.lastname: Stevenson
authors.forename: Paul
authors.initials: P
authors.lastname: Jarvis
mesh_terms: D029681:Arabidopsis Proteins; D002843:Chromatin / Q000235:genetics*; D002868:Chromosomal Proteins, Non-Histone / Q000502:physiology; D019175:DNA Methylation; D004268:DNA-Binding Proteins / Q000502:physiology; D020868:Gene Silencing; D034622:RNA Interference / Q000502:physiology*; D012330:RNA, Double-Stranded / Q000502:physiology; D012568:Schizosaccharomyces / Q000235:genetics; D029702:Schizosaccharomyces pombe Proteins / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology
chemical_list: D029681:Arabidopsis Proteins; D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; C118957:DDM1 protein, Arabidopsis; D004268:DNA-Binding Proteins; D012330:RNA, Double-Stranded; D029702:Schizosaccharomyces pombe Proteins; C465958:Swi6 protein, S pombe; D014157:Transcription Factors