title: Coxa vara with proximal femoral growth arrest in patients who had neonatal extracorporeal membrane oxygenation.
abstract: This is a retrospective review of four patients in whom a pattern of coxa vara with proximal femoral growth arrest and metaphyseal irregularities developed. These patients were all treated with neonatal extracorporeal membrane oxygenation and presented with a progressive gait disturbance and pain, leg-length discrepancy, and limited abduction. Imaging revealed coxa vara with proximal femoral growth arrest. Two patients (three hips) underwent proximal femoral valgus osteotomy, one patient underwent fixation of a femoral neck fracture with subsequent greater trochanter transfer, and one patient is being observed. This case series suggests an association between neonatal extracorporeal membrane oxygenation and this unusual pattern of coxa vara with proximal femoral growth arrest.
authors.affiliation: Children's Hospital, Boston, Massachusetts 02115, USA. Rachel.Difazio@tch.harvard.edu
authors.forename: Rachel L
authors.initials: RL
authors.lastname: DiFazio
authors.forename: Minider S
authors.initials: MS
authors.lastname: Kocher
authors.forename: Sigurd
authors.initials: S
authors.lastname: Berven
authors.forename: James
authors.initials: J
authors.lastname: Kasser
mesh_terms: D002370:Casts, Surgical; D004839:Epiphyses, Slipped / Q000000981:diagnostic imaging / Q000601:surgery*; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects* / Q000379:methods; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging / Q000254:growth & development*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007870:Leg Length Inequality / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D008297:Male; D010027:Osteotomy / Q000379:methods; D011859:Radiography; D016059:Range of Motion, Articular; D020127:Recovery of Function; D012127:Respiratory Distress Syndrome, Newborn / Q000175:diagnosis / Q000628:therapy*; D012189:Retrospective Studies; D018570:Risk Assessment; D016896:Treatment Outcome