title: Penetration of drug resistance in Escherichia coli isolated from laboratory animals.
abstract: A total of 713 strains of fecal Escherichia coli (E. coli) isolated from laboratory animals in the colonies of 4 research laboratories and 4 commercial breeders in Japan in 1994 were examined in regard to resistance to 8 antibacterial agents. The incidence of resistance to sulfadimethoxine (Su), streptomycin (Sm), ampicillin, cephaloridine, tetracycline, chloramphenicol, kanamycin, and gentamicin was 99.9%, 32.5%, 6.7%, 0.7%, 7.0%, 2.6%, 6.6% and 0.7%, respectively. These results indicated that Su and Sm resistance are penetrating into normal E. coli strains isolated from laboratory animals.
authors.affiliation: Laboratory Animal Center, Keio University School of Medicine. Tokyo, Japan.
authors.forename: Kouji
authors.initials: K
authors.lastname: Shimoda
authors.forename: Jun
authors.initials: J
authors.lastname: Kimura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Oguri
authors.forename: Naoko
authors.initials: N
authors.lastname: Nakamura
authors.forename: Toru
authors.initials: T
authors.lastname: Urano
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Maejima
mesh_terms: D000818:Animals; D000830:Animals, Laboratory / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification*; D005243:Feces / Q000382:microbiology; D006168:Guinea Pigs; D007564:Japan; D051379:Mice; D011817:Rabbits; D051381:Rats
chemical_list: D000900:Anti-Bacterial Agents