title: Glomerular changes in hereditary single-gene diseases.
abstract: Molecular genetics has strongly influenced clinical medicine and particularly nephrology. Several gene mutations of single-gene hereditary nephropathies have been recently identified. These data are useful to develop methods of diagnosis and treatment, but also to understand the pathogenesis of these particular disorders. In this review we focused on several monogenic hereditary renal diseases inducing nephrotic syndrome and other hereditary diseases with renal involvement and progression towards end-stage renal failure.
authors.affiliation: Department of Nephrology and Dialysis, Vimercate Hospital, Milan, Italy. adsess@tin.it
authors.forename: Adalberto
authors.initials: A
authors.lastname: Sessa
authors.forename: Mietta
authors.initials: M
authors.lastname: Meroni
authors.forename: Graziana
authors.initials: G
authors.lastname: Battini
authors.forename: Alessia
authors.initials: A
authors.lastname: Maglio
authors.forename: Marco
authors.initials: M
authors.lastname: Righetti
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Fabris
authors.forename: Manuela
authors.initials: M
authors.lastname: Nebuloni
authors.forename: Francesco
authors.initials: F
authors.lastname: Pallotti
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Giordano
authors.forename: Antonella
authors.initials: A
authors.lastname: Tosoni
mesh_terms: D030342:Genetic Diseases, Inborn / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D007674:Kidney Diseases / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology*; D007678:Kidney Glomerulus / Q000473:pathology* / Q000503:physiopathology*