Postmalaria neurological syndrome: two cases from the Gambia.
We describe 2 patients with severe Plasmodium falciparum malaria whose convalescence was complicated by fever, with acute confusion and acalculia in one patient and a triad of myoclonus, tremor, and dysphasia in the other. Inflammatory changes were found in cerebrospinal fluid samples. Postmalaria neurological syndrome was diagnosed in each patient, and a therapeutic response to oral corticosteroids was seen in the second patient.
Lawn
Stephen D
SD
The Hospital for Tropical Diseases, London WC1E 6AU, United Kingdom. stevelawn@yahoo.co.uk
Flanagan
Katie L
KL
Wright
Stephen G
SG
Doherty
Tom F
TF
Godfrey-Faussett
Peter
P
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000818:Animals; D005260:Female; D005714:Gambia; D006801:Humans; D008288:Malaria / Q000150:complications* / Q000469:parasitology; D008297:Male; D009422:Nervous System Diseases / Q000188:drug therapy / Q000209:etiology*; D010963:Plasmodium falciparum; D013577:Syndrome
D000305:Adrenal Cortex Hormones