Malignant mixed mesodermal tumor in a young woman with polycystic ovary syndrome. A case report.
BACKGROUND
Malignant mixed mesodermal tumors (MMMTs) are uncommon, highly aggressive tumors of the uterus composed of both carcinomatous and sarcomatous elements, both likely to be derived from the same original stem cell. There is a strong association between endometrial adenocarcinoma and polycystic ovary disease. However, only two cases of MMMT occurring in women with polycystic ovaries have been reported.


METHODS
A 36-year-old woman with polycystic ovary disease developed an MMMT of the endometrium.


CONCLUSIONS
Some cases of MMMT may be estrogen related.
Karabakhtsian
Rouzan
R
Departments of Pathology, Laboratory Medicine and Obstetrics, Gynecology and Women's Health, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA. hellerds@umdnj.edu
Heller
Debra S
DS
Singhal
Pankaj
P
Sama
Jahir
J
D000328:Adult; D000740:Anemia / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D018199:Mixed Tumor, Mesodermal / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D014592:Uterine Hemorrhage / Q000209:etiology; D014594:Uterine Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery