title: Treatment models for those with severe mental illness and comorbid personality disorder.
abstract: BACKGROUND
  Dual diagnosis of personality disorder and severe mental illness is an important clinical association that has been under-researched with regard to clinical management.
  
  
  OBJECTIVE
  To compare the outcomes of different treatment models.
  
  
  METHODS
  The outcome of patients with this combined diagnosis was compared in a systematic review of three randomised controlled trials in which different forms of community outreach treatment or intensive case management were compared with standard care.
  
  
  RESULTS
  The results from the three studies showed that the outcome of comorbid diagnoses was worse than that of single diagnoses. Although assertive approaches reduced in-patient care, they sometimes did so at the expense of increasing social dysfunction and behavioural disturbance.
  
  
  CONCLUSIONS
  For those with comorbid severe mental illness and personality disorder, the policy of assertive outreach and care in community settings may be inappropriate for both public and patients unless modified to take account of the special needs of this group.
authors.affiliation: Department of Psychological Medicine, Imperial College, London, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Tyrer
authors.forename: Shaeda
authors.initials: S
authors.lastname: Simmonds
mesh_terms: D003156:Community Mental Health Services / Q000379:methods; D015897:Comorbidity; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay / Q000639:trends; D010554:Personality Disorders / Q000150:complications / Q000628:therapy*; D016495:Police; D011618:Psychotic Disorders / Q000150:complications / Q000628:therapy; D016032:Randomized Controlled Trials as Topic; D012559:Schizophrenia / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome