WormBase: a cross-species database for comparative genomics.
WormBase (http://www.wormbase.org/) is a web-accessible central data repository for information about Caenorhabditis elegans and related nematodes. The past two years have seen a significant expansion in the biological scope of WormBase, including the integration of large-scale, genome-wide data sets, the inclusion of genome sequence and gene predictions from related species and active literature curation. This expansion of data has also driven the development and refinement of user interfaces and operability, including a new Genome Browser, new searches and facilities for data access and the inclusion of extensive documentation. These advances have expanded WormBase beyond the obvious target audience of C. elegans researchers, to include researchers wishing to explore problems in functional and comparative genomics within the context of a powerful genetic system.
Harris
Todd W
TW
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.
Lee
Raymond
R
Schwarz
Erich
E
Bradnam
Keith
K
Lawson
Daniel
D
Chen
Wen
W
Blasier
Darin
D
Kenny
Eimear
E
Cunningham
Fiona
F
Kishore
Ranjana
R
Chan
Juancarlos
J
Muller
Hans-Michael
HM
Petcherski
Andrei
A
Thorisson
Gudmundur
G
Day
Allen
A
Bieri
Tamberlyn
T
Rogers
Anthony
A
Chen
Chao-Kung
CK
Spieth
John
J
Sternberg
Paul
P
Durbin
Richard
R
Stein
Lincoln D
LD
D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000196:embryology / Q000235:genetics* / Q000254:growth & development; D018509:DNA, Helminth / Q000032:analysis; D003625:Data Collection; D030561:Databases, Nucleic Acid; D020224:Expressed Sequence Tags; D015870:Gene Expression; D023281:Genomics; D016247:Information Storage and Retrieval; D009474:Neurons / Q000145:classification; D020641:Polymorphism, Single Nucleotide; D011786:Quality Control; D034622:RNA Interference; D018510:RNA, Helminth / Q000037:antagonists & inhibitors; D012689:Sequence Homology, Nucleic Acid
D018509:DNA, Helminth; D018510:RNA, Helminth