title: An antiplasmodial lignan from Euterpe precatoria.
abstract: As a part of a study on new antiplasmodial natural products, a new 8-5' linked lignan dehydrodiconiferyl dibenzoate (2) and p-hydroxybenzoic acid (1) were isolated from the roots of the palm Euterpe precatoria. In contrast to compound 1, compound 2 showed a moderate antiplasmodial activity.
authors.affiliation: Department of Medicinal Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark.
authors.forename: Janne Funder
authors.initials: JF
authors.lastname: Jensen
authors.forename: Lars Peter
authors.initials: LP
authors.lastname: Kvist
authors.forename: Søren Brøgger
authors.initials: SB
authors.lastname: Christensen
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000494:pharmacology; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D010568:Peru; D018517:Plant Roots; D010946:Plants, Medicinal / Q000737:chemistry*; D010963:Plasmodium falciparum / Q000187:drug effects*
chemical_list: D000962:Antimalarials; D062385:Hydroxybenzoates; D017705:Lignans; C473437:dehydrodiconiferyl dibenzoate