title: Commentary: eye movement research with clinical populations.
abstract: The preceding set of chapters span the disciplines of neurology and psychiatry, and provide a diverse introduction to clinical eye movement research. They illustrate how oculomotor paradigms can be used to learn about acute and chronic perturbations in brain function, disturbances in brain development, disturbances in sensorimotor as well as cognitive systems, and the effects of therapeutic and illicit drugs on brain function. This commentary discusses these contributions, provides an overview of broad methodological issues involved in applying eye movement studies to psychiatric populations using the antisaccade task as an exemplar, and considers the potential of collaborations between eye movement and brain imaging researchers to advance understanding of clinical eye movement abnormalities and of what they reveal about the organization of the oculomotor system.
authors.affiliation: Center for Cognitive Medicine, Departments of Psychiatry, Neurology and Psychology, University of Illinois at Chicago, MC 913, 912 S. Wood St., Neuropsychiatric Institute, Chicago, IL 60612, USA. jsweeney@psych.uic.edu
authors.forename: John A
authors.initials: JA
authors.lastname: Sweeney
authors.forename: Deborah
authors.initials: D
authors.lastname: Levy
authors.forename: Margret S H
authors.initials: MS
authors.lastname: Harris
mesh_terms: D001921:Brain / Q000473:pathology / Q000502:physiology; D005133:Eye Movements / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D001523:Mental Disorders / Q000150:complications; D008959:Models, Neurological; D009422:Nervous System Diseases / Q000150:complications; D015835:Ocular Motility Disorders / Q000209:etiology / Q000503:physiopathology*; D012106:Research