Dynamic aspects of cadherin-mediated adhesion in synapse development and plasticity.
Cadherins are calcium-dependent cell adhesion molecules that are enriched at synapses. Recent studies indicate important functional roles in synaptic targeting during brain development, and in regulating functional and structural aspects of synaptic plasticity and neural repair throughout life.
Huntley
George W
GW
Fishberg Research Center for Neurobiology, The Mount Sinai School of Medicine of New York University, 1425 Madison Ave, New York, NY 10029, USA. george.huntley@mssm.edu
D000818:Animals; D001921:Brain / Q000166:cytology; D015820:Cadherins / Q000737:chemistry / Q000502:physiology*; D002448:Cell Adhesion; D006801:Humans; D009416:Nerve Regeneration; D009474:Neurons / Q000166:cytology / Q000648:ultrastructure; D013569:Synapses / Q000737:chemistry / Q000648:ultrastructure*
D015820:Cadherins