title: Postoperative complication rates after hepatic resection in Maryland hospitals.
abstract: OBJECTIVE
  High-volume centers provide superior quality care and therefore have a lower incidence of postoperative complications.
  
  
  METHODS
  Observational statewide administrative database.
  
  
  METHODS
  State of Maryland, nonfederal acute-care hospital (n = 52), performing liver resection (n = 35).
  
  
  METHODS
  All patients discharged after undergoing hepatic resection from 1994 to 1998 (N = 569).
  
  
  METHODS
  Two sequential analyses using multiple logistic regression of in-hospital mortality were performed to determine the relative importance of preoperative case-mix and postoperative complications.
  
  
  RESULTS
  The overall in-hospital mortality rate was 4.8% and was significantly lower in high-volume hospitals (2.8%) than in low-volume hospitals (10.2%) (P<.001). After adjusting for case-mix in the multivariate analysis, low hospital volume was associated with a 3-fold increase in mortality (odds ratio, 3.1; 95% confidence interval [CI], 1.2-7.6; P =.02). Having surgery at a low-volume hospital was associated with increased rates of several postoperative complications: reintubation (relative risk [RR], 2.5; 95% CI, 1.8-3.4), pulmonary failure (RR, 2.3; 95% CI, 1.6-3.5), pneumonia (RR, 0.35; 95% CI, 1.0-5.6), acute renal failure (RR, 2.0; 95% CI, 1.1-3.7), acute myocardial infarction (RR, 2.6; 95% CI, 1.2-5.9), and aspiration (RR, 1.4; 95% CI, 0.9-2.0). When considering all other factors using statistical methods, hospital volume was no longer associated with mortality.
  
  
  CONCLUSIONS
  Patients who undergo hepatic resection at low-volume hospitals are at a higher risk of postoperative complications and death than those who have the same operation at high-volume hospitals. The empirical difference between outcomes at high- and low-volume hospitals seems to be due to a variation in postoperative complications.
authors.affiliation: Department of Surgery, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Justin B
authors.initials: JB
authors.lastname: Dimick
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Pronovost
authors.forename: John A
authors.initials: JA
authors.lastname: Cowan
authors.forename: Pamela A
authors.initials: PA
authors.lastname: Lipsett
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects* / Q000401:mortality / Q000706:statistics & numerical data*; D017721:Hospital Costs; D017052:Hospital Mortality; D006761:Hospitals / Q000592:standards* / Q000706:statistics & numerical data*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008396:Maryland / Q000453:epidemiology; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000191:economics / Q000592:standards*; D011183:Postoperative Complications / Q000191:economics / Q000453:epidemiology* / Q000401:mortality; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors