title: Pituitary surgery complicated by haemorrhagic necrosis of residual tumour.
abstract: Haemorrhagic necrosis of residual pituitary tumour following partial excision has not previously been well described. This is differentiated from post-operative sellar haematoma due to inadequate haemostasis on the basis of absent free clot. The authors report two cases of large macroadenomas with significant supra-sellar extension which were complicated by haemorrhagic necrosis of residual tumour following initial surgery. The literature is reviewed and possible pathophysiogical mechanisms are discussed.
authors.affiliation: Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, South Australia, Australia. gabriellee@ozemail.com.au
authors.forename: G Y
authors.initials: GY
authors.lastname: Lee
authors.forename: P L
authors.initials: PL
authors.lastname: Reilly
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000601:surgery*; D000328:Adult; D000368:Aged; D013507:Endocrine Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006406:Hematoma / Q000175:diagnosis / Q000209:etiology; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009336:Necrosis; D018365:Neoplasm, Residual / Q000098:blood supply* / Q000175:diagnosis / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000601:surgery*; D014057:Tomography, X-Ray Computed