Hallucinations and sleep-wake cycle in PD: a 24-hour continuous polysomnographic study.
Twenty-four-hour ambulatory polysomnography was performed in 20 patients with PD who were having visual hallucinations (12 men and 8 women, mean age 70 +/- 6 years). Visual hallucinations were clearly related to daytime NREM sleep or nocturnal REM sleep in 33% of the instances. The data reinforce the hypothesis that neural mechanisms implicated in generating sleep and, in particular, in dream imagery play a role in the occurrence of visual hallucinations in PD.
Manni
R
R
Unit of Sleep Medicine, IRCCS C. Mondino Institute of Neurology, Pavia, Italy.
Pacchetti
C
C
Terzaghi
M
M
Sartori
I
I
Mancini
F
F
Nappi
G
G
D000368:Aged; D004569:Electroencephalography; D005260:Female; D006212:Hallucinations / Q000209:etiology*; D006801:Humans; D008297:Male; D018670:Monitoring, Ambulatory; D010300:Parkinson Disease / Q000150:complications / Q000523:psychology*; D017286:Polysomnography; D012890:Sleep / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology; D014851:Wakefulness / Q000502:physiology*