title: Rfam: an RNA family database.
abstract: Rfam is a collection of multiple sequence alignments and covariance models representing non-coding RNA families. Rfam is available on the web in the UK at http://www.sanger.ac.uk/Software/Rfam/ and in the US at http://rfam.wustl.edu/. These websites allow the user to search a query sequence against a library of covariance models, and view multiple sequence alignments and family annotation. The database can also be downloaded in flatfile form and searched locally using the INFERNAL package (http://infernal.wustl.edu/). The first release of Rfam (1.0) contains 25 families, which annotate over 50 000 non-coding RNA genes in the taxonomic divisions of the EMBL nucleotide database.
authors.affiliation: The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. sgj@sanger.ac.uk
authors.forename: Sam
authors.initials: S
authors.lastname: Griffiths-Jones
authors.forename: Alex
authors.initials: A
authors.lastname: Bateman
authors.forename: Mhairi
authors.initials: M
authors.lastname: Marshall
authors.forename: Ajay
authors.initials: A
authors.lastname: Khanna
authors.forename: Sean R
authors.initials: SR
authors.lastname: Eddy
mesh_terms: D000818:Animals; D030561:Databases, Nucleic Acid; D020407:Internet; D022661:RNA, Untranslated / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D016415:Sequence Alignment; D012984:Software
chemical_list: D022661:RNA, Untranslated