title: Linear scleroderma en coup de sabre and brain calcification: is there a pathogenic relationship?
abstract: Extracutaneous calcifications are rare in scleroderma and related conditions. We describe a female patient with linear scleroderma en coup de sabre and a longstanding clinical history of tonic and clonic convulsions. Radiographic study showed extensive cerebral calcifications in the right occipital hemisphere, homolateral to the involved side of her face. This report further suggests a relationship between localized scleroderma and neurological manifestations. Brain imaging studies should be routinely performed in scleroderma patients exhibiting neurological manifestations, especially seizure disorder.
authors.affiliation: Department of Medicine, Sections of Rheumatology, Louisiana State University Health Sciences Center, New Orleans 70112, USA.
authors.forename: Diana Elsa
authors.initials: DE
authors.lastname: Flores-Alvarado
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Esquivel-Valerio
authors.forename: Mario
authors.initials: M
authors.lastname: Garza-Elizondo
authors.forename: Luis R
authors.initials: LR
authors.lastname: Espinoza
mesh_terms: D000328:Adult; D000506:Alopecia Areata / Q000473:pathology; D002114:Calcinosis / Q000473:pathology*; D004830:Epilepsy, Tonic-Clonic / Q000473:pathology*; D005260:Female; D006801:Humans; D009778:Occipital Lobe / Q000473:pathology*; D012535:Scalp / Q000473:pathology*; D012594:Scleroderma, Localized / Q000473:pathology*; D014057:Tomography, X-Ray Computed