[Diagnostic value of the ultrasound screening for osteoporosis in postmenopausal women].
Quantitative ultrasound (QUS) of the calcaneus quickly introduced itself as a useful diagnostic tool in osteoporosis. The purpose of this study was to assess its diagnostic value in postmenopausal women as compared to DXA of vertebral bodies. 100 postmenopausal women (mean age 48 years) were included and underwent calcaneal QUS (Lunar Achilles+ device) and dual-energy X-ray absorptiometry of the vertebral bodies (Hologic QDR 4500 A unit). Mean QUS T-score was -2.38, and mean DXA T-score was -2.06 standard deviations. Both measurements classified equal proportions of women as normal (4 versus 12%), osteopenic (55% in both cases), and osteoporotic (41 versus 33%). In detecting osteoporosis QUS showed 58% sensitivity and 47% specificity. When assessing fracture risk (osteoporosis and osteopenia) QUS showed 100% sensitivity and 92% specificity. The negative predictive value of QUS always exceeded the positive one. QUS is a valuable tool in primary screening for increased fracture risk. Alerting results require further examinations.
Boianov
M
M
Temelkova
N
N
Popivanov
P
P
D015502:Absorptiometry, Photon; D015519:Bone Density; D005260:Female; D006801:Humans; D016014:Linear Models; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011237:Predictive Value of Tests; D012016:Reference Values; D012307:Risk Factors; D014463:Ultrasonography