title: Osteosarcoma of bone in apatient with primary hyperparathyroidism: a case report.
abstract: A 69-year-old woman was diagnosed with a malignant tumor of the right proximal femur. She had primary hyperparathyroidism and chronic elevation of parathyroid hormone levels (PTH > 1,000 pg/ml). She underwent resection of the bone lesion; histological analysis showed a high-grade fibroblastic osteosarcoma. In addition, she underwent curative resection of a large left superior parathyroid adenoma. To our knowledge, this is the third reported clinical case of osteosarcoma arising in association with hyperparathyroidism.
authors.affiliation: Department of Medicine Endocrinology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: M
authors.initials: M
authors.lastname: Betancourt
authors.forename: K L
authors.initials: KL
authors.lastname: Wirfel
authors.forename: A K
authors.initials: AK
authors.lastname: Raymond
authors.forename: A W
authors.initials: AW
authors.lastname: Yasko
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.forename: R
authors.initials: R
authors.lastname: Vassilopoulou-Sellin
mesh_terms: D000236:Adenoma / Q000150:complications; D000368:Aged; D005260:Female; D005266:Femoral Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D012516:Osteosarcoma / Q000150:complications* / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000150:complications
chemical_list: D010281:Parathyroid Hormone