title: Safety and efficacy of a non-steroidal anti-androgen, based on results of a post marketing surveillance of nilutamide.
abstract: The use, tolerability and efficacy of the non-steroidal anti-androgen nilutamide (Anandron(R)) in daily clinical practice was investigated in this 5-y project. In total 725 patients were recruited from 27 Dutch centres. The investigated population was very heterogeneous and different therapeutic options were reported. We may conclude that in general good results have been obtained, especially in first line combination therapy combined with luteinising hormone releasing hormone (LHRH) agonists. Patients with a good performance status at inclusion seem to benefit more from nilutamide combination therapy.Prostate Cancer and Prostatic Diseases (2001) 4, 112-117
authors.affiliation: Medical Department, Aventis Pharma B.V., Hoevelaken, The Netherlands.
authors.forename: E M C
authors.initials: EM
authors.lastname: Schasfoort
authors.forename: C
authors.initials: C
authors.lastname: Van De Beek
authors.forename: D W W
authors.initials: DW
authors.lastname: Newling