title: Demonstration of declining community prevalence of Chlamydia trachomatis infection using sentinel surveillance.
abstract: BACKGROUND
  Chlamydia trachomatis infection rates in Alabama increased dramatically from 1996 to 1998, due in part to expanded screening. Detection of prevalent infection through increased testing could mask timely detection of the impact of screening programs on community prevalence.
  
  
  OBJECTIVE
  The goal of the study was to evaluate the temporal trend in prevalence among women aged 15 to 34 years attending reproductive healthcare clinics in Birmingham, Alabama.
  
  
  METHODS
  Between 1995 and 1998, systematic screening of the first 60 women presenting each month to each of six participating clinics was performed with urine-based testing for chlamydia.
  
  
  RESULTS
  In contrast to the 218% increase in chlamydia prevalence detected through passive surveillance, during the study period surveillance in sentinel sites revealed that first-visit chlamydia prevalence declined from 12.8% to 8.6%.
  
  
  CONCLUSIONS
  Sentinel site surveillance served as a valuable adjunct to passive surveillance for determining the true trend of chlamydia prevalence during the hyperendemic phase of a local epidemic.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA. lbachmann@idmail.dom.uab.edu
authors.forename: Laura H
authors.initials: LH
authors.lastname: Bachmann
authors.forename: Maurizio
authors.initials: M
authors.lastname: Macaluso
authors.forename: Edward W
authors.initials: EW
authors.lastname: Hook
mesh_terms: D000293:Adolescent; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data; D017677:Age Distribution; D000407:Alabama / Q000453:epidemiology; D000554:Ambulatory Care Facilities; D002690:Chlamydia Infections / Q000453:epidemiology* / Q000208:ethnology / Q000209:etiology / Q000517:prevention & control*; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005260:Female; D006801:Humans; D015995:Prevalence; D018571:Sentinel Surveillance; D044465:White People / Q000706:statistics & numerical data