title: Marriage of XAFS and crystallography for structure-function studies of metalloproteins.
abstract: Metalloproteins constitute a significant proportion of all known genomes. In this Article it is shown that the marriage of two synchrotron-radiation-based structural techniques, namely high-resolution crystallography and XAFS, can yield unprecedented levels of structural information that is directly relevant to the mechanism/function of these important macromolecules.
authors.affiliation: College of Biology and Medicine, CLRC Daresbury Laboratory, Warrington WA4 4AD, UK. s.hasnain@dl.ac.uk
authors.forename: S Samar
authors.initials: SS
authors.lastname: Hasnain
authors.forename: Richard W
authors.initials: RW
authors.lastname: Strange
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D001665:Binding Sites; D003300:Copper; D018360:Crystallography, X-Ray / Q000379:methods; D008667:Metalloproteins / Q000737:chemistry*; D008958:Models, Molecular; D011487:Protein Conformation; D017433:Protein Structure, Secondary
chemical_list: D008667:Metalloproteins; D003300:Copper