title: Pneumonitis associated with Ureaplasma urealyticum in children with cancer.
abstract: We describe 3 pediatric patients with cancer who had clinical and radiographic evidence of pneumonitis and for whom cultures of bronchoalveolar lavage fluid specimens yielded Ureaplasma urealyticum. Two of the patients died; for the surviving patient, clinical improvement coincided temporally with administration of erythromycin. Immunocompromised patients with pneumonitis of unclear etiology should have respiratory secretions cultured for mycoplasmas and should receive empiric therapy that includes a macrolide antibiotic.
authors.affiliation: Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA. sbuckingham@utmem.edu
authors.forename: Steven C
authors.initials: SC
authors.lastname: Buckingham
authors.forename: Dennis T
authors.initials: DT
authors.lastname: Crouse
authors.forename: Katherine M
authors.initials: KM
authors.lastname: Knapp
authors.forename: Christian C
authors.initials: CC
authors.lastname: Patrick
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000134:cerebrospinal fluid / Q000150:complications* / Q000382:microbiology; D018410:Pneumonia, Bacterial / Q000134:cerebrospinal fluid / Q000150:complications / Q000382:microbiology*; D016990:Ureaplasma urealyticum / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D004917:Erythromycin