title: The cyclooxygenase reaction mechanism.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Ave, Urbana, Illinois 61801, USA. vddonk@uiuc.edu
authors.forename: Wilfred A
authors.initials: WA
authors.lastname: van der Donk
authors.forename: Ah-Lim
authors.initials: AL
authors.lastname: Tsai
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Kulmacz
mesh_terms: D000818:Animals; D016718:Arachidonic Acid / Q000737:chemistry*; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; D005609:Free Radicals / Q000737:chemistry; D006801:Humans; D007527:Isoenzymes / Q000737:chemistry; D008565:Membrane Proteins; D008968:Molecular Conformation; D009195:Peroxidase / Q000737:chemistry; D011451:Prostaglandin-Endoperoxide Synthases / Q000737:chemistry*; D011462:Prostaglandins G / Q000737:chemistry*; D014443:Tyrosine / Q000737:chemistry
chemical_list: D005609:Free Radicals; D007527:Isoenzymes; D008565:Membrane Proteins; D011462:Prostaglandins G; C408694:tyrosine radical; D016718:Arachidonic Acid; D014443:Tyrosine; C038291:prostaglandin G2; D009195:Peroxidase; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; C496511:PTGS1 protein, human; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases; C466421:cyclooxygenase-3