[Various immunological aspects of ulcer formation (a literature review)].
The duodenal ulcerative disease is accompanied by increase of blood serum interleukins, that is manifested not by only local, but also by common response of organism to damage. It is evidence of activation of T- and B-lymphocytes, endothelial and epithelial cells, of stimulation of apoptosis processes, of cellular differentiation and proliferation playing the important role in regeneration of duodenal mucous membrane. Therefore the definition of interleukin profile for ulcerative disease can have a prognostic value, as it allows to receive additional information regarding to activity of disease, its prognosis and respectively to efficiency of treatment.
Dubtsova
E A
EA
Central Scientific Research Institute of Gastroenterology, Moscow.
D006801:Humans; D014456:Ulcer / Q000209:etiology* / Q000276:immunology* / Q000473:pathology