title: [The role of immunological factors in Meniere's disease].
abstract: Involvement of the immunological mechanisms in the pathogenesis of Meniere's disease has been discussed over the past two decades. Nevertheless, we lack well-defined laboratory tests that might confirm the autoimmune background of the disorder. Therefore the diagnosis is often based solely on the patient's clinical profile and the positive response to the immunosuppressive therapy. In this article we present a case of 44 year-old woman with Meniere's disease successfully treated with systemic glucocorticoids. The pathogenesis, diagnosis and management of immune-mediated cases of Meniere's disease are reviewed.
authors.affiliation: Katedra i Klinika Otolaryngologii AM w Warszawie.
authors.forename: Irena
authors.initials: I
authors.lastname: Krzeska-Malinowska
authors.forename: Marta
authors.initials: M
authors.lastname: Held-Ziółkowska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Kowalska
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Niemczyk
mesh_terms: D000328:Adult; D015551:Autoimmunity; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008575:Meniere Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D011241:Prednisone / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D007166:Immunosuppressive Agents; D011241:Prednisone