title: Expression of occ1 mRNA in the visual cortex during postnatal development in macaques.
abstract: We previously reported that the occ1 gene is specifically expressed in the primary visual cortex of adult monkeys in an activity-dependent manner (Tochitani et al., Eur. J. Neurosci., 3, 297-307, 2001). In this report, we compared occ1 mRNA expression in the primary visual cortex during the development of newborn, 3-month-old and adult monkeys. occ1 mRNA was already expressed preferentially in the primary visual cortex of newborn monkeys, but the laminar pattern of occ1 expression in the visual cortex changed as development proceeded. This suggests the possible importance of experience-dependent developmental regulations of occ1 in the developing primary visual cortex.
authors.affiliation: Division of Speciation Mechanisms I, National Institute for Basic Biology, Okazaki, Aichi 444-8585, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Tochitani
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Hashikawa
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Yamamori
mesh_terms: D000375:Aging; D000818:Animals; D038702:Follistatin-Related Proteins / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D008251:Macaca; D008252:Macaca fascicularis; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic; D014793:Visual Cortex / Q000254:growth & development*
chemical_list: D038702:Follistatin-Related Proteins; C448721:OCC1 protein, Macaca fascicularis; D012333:RNA, Messenger