title: [Analysis of serologic typing error for HLA-A and HLA-B in Chinese].
abstract: Serological mistypings of HLA-A and HLA-B in 27 cases were analyzed. The results showed that for HLA-A and HLA-B typing, the rates of incorrect antigen assignments were significantly higher than rates of antigen misses (P < 0.05), but there was no significant difference between HLA-A and HLA-B typings. The frequencies of miss-assigned HLA-A and HLA-B specificities were A1 (66.7%), A3 (50.0%), A11 (13.5%), A9 (11.8%), A19 (7.1%), and B16 (50.0%), B48 (43.9%), B15 (16.7%), B40 (11.1%), B13 (10.0%) and B17 (9.1%). In conclusion, the serologic and DNA-based typing techniques should be reciprocally complementary in HLA-A and HLA-B typing.
authors.affiliation: Nanjing Red Cross Blood Center, Nanjing 210008, China.
authors.forename: Yu-Dong
authors.initials: YD
authors.lastname: Dai
authors.forename: Qi-Jun
authors.initials: QJ
authors.lastname: Sun
authors.forename: Yi-Hong
authors.initials: YH
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Yuan
authors.forename: Bo
authors.initials: B
authors.lastname: Meng
mesh_terms: D044466:Asian People; D002681:China; D015234:HLA-A Antigens / Q000145:classification* / Q000235:genetics; D015235:HLA-B Antigens / Q000145:classification* / Q000235:genetics; D006801:Humans; D012703:Serotyping
chemical_list: D015234:HLA-A Antigens; D015235:HLA-B Antigens