A human tissue and data resource: an overview of opportunities, challenges, and development of a provider/researcher partnership model.
As we continue to strive to apply the findings of in vitro and animal studies to human disease and transition from genomics to proteomics, we will experience an ever-increasing need for human tissues. A web based system that provides access to tissues repositories and associated data will best facilitate the access to these vital resources and the application of research information to human disease treatment. There are organizational and design requirements that must be addressed in the implementation of the infrastructures that are needed to implement such a system, with special attention paid to the protection of patient anonymity. This report describes the implementation of a prototype human tissue network in the hope of encouraging implementation of similar systems among other consortia of providers and researchers.
Kort
Eric J
EJ
Special Program in Analytical, Cellular, and Molecular Microscopy, Van Andel Research Institute, 333 Bostwick, NE, Grand Rapids, MI 49503, USA.
Campbell
Bryon
B
Resau
James H
JH
D000818:Animals; D019295:Computational Biology; D003195:Computer Communication Networks; D016494:Computer Security; D003219:Confidentiality; D003625:Data Collection; D016208:Databases, Factual; D023281:Genomics; D006801:Humans; D007258:Informed Consent; D020407:Internet; D010336:Pathology / Q000379:methods / Q000706:statistics & numerical data; D040901:Proteomics; D014015:Tissue Banks / Q000706:statistics & numerical data*