[Serum levels of erythropoietin and transferrin receptor in thalassemia of the Li nationality].
immunosorbent To determine serum EPO and soluble transferrin receptor (sTfR) level and to assess the degree of erythropoietic proliferation in patients with thalassemia of Li nationality, 50 cases and 50 normal individuals were studied. Enzyme-linked immunosorbent assay was used for EPO and sTfR. Results showed that serum EPO and sTfR levels in beta-thalasemia major patients were significantly higher than those in normal control group, and no significant difference in beta-thalassemia minor cases with those in control. It is concluded that increase of serum EPO and sTfR level is related to the type of thalassemia.
Yao
Hong-Xia
HX
Department of Hematology, The Affiliated Hospital of Hainan Medical College, Haikou 570102, China. dypyhx@public.hk.hi.cn
Chen
Zhi-Bin
ZB
Ding
Yi-Peng
YP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002681:China / Q000208:ethnology; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011990:Receptors, Transferrin / Q000097:blood*; D013789:Thalassemia / Q000097:blood*
D011990:Receptors, Transferrin; D004921:Erythropoietin