Clostridium difficile brain empyema after prolonged intestinal carriage.
Clostridium difficile, the most common cause of antibiotic-associated diarrhea, is occasionally isolated from extraintestinal sites and is usually found as part of a polymicrobial flora. We report a case of brain empyema that occurred after the recurrent intestinal carriage of a nontoxigenic strain of C. difficile. Brain abscess cultures contained both toxigenic and nontoxigenic isolates. Pulsed-field gel electrophoresis showed that nontoxigenic isolates from the intestine and from the brain were identical.
Gravisse
J
J
Service of Bacteriology-Virology, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Barnaud
G
G
Hanau-Berçot
B
B
Raskine
L
L
Riahi
J
J
Gaillard
J L
JL
Sanson-Le-Pors
M J
MJ
D001927:Brain Diseases / Q000209:etiology / Q000382:microbiology*; D016360:Clostridioides difficile / Q000302:isolation & purification*; D016521:Electrophoresis, Gel, Pulsed-Field; D004653:Empyema / Q000209:etiology / Q000382:microbiology*; D004761:Enterocolitis, Pseudomembranous / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged