Potassium superoxide as an alternative reagent for Winterfeldt oxidation of beta-carbolines.
Potassium superoxide was examined as an alternative oxidation reagent for the Winterfeldt reaction. KO(2) was found to be superior to the original Winterfeldt protocol for base-sensitive substrates. [reaction--see text]
Jiang
Weiqin
W
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., 1000 Route 202 South, P.O. Box 300, Raritan, NJ 08869, USA. Wjiang1@prdus.jnj.com
Zhang
Xuqing
X
Sui
Zhihua
Z
D002243:Carbolines / Q000737:chemistry*; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry*; D010726:Phosphodiesterase Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry*; D013481:Superoxides / Q000737:chemistry*
D002243:Carbolines; D016877:Oxidants; D010726:Phosphodiesterase Inhibitors; D013481:Superoxides; C039316:potassium superoxide