Aspergillosis. Pathogenesis, clinical manifestations, and therapy.
Diseases caused by Aspergillus species are increasing in importance, especially among immunocompromised hosts. Clinical manifestations are variable, ranging from allergic to invasive disease, largely depending on the status of the host's immune system. This article focuses on the pathogenesis and clinical manifestations of diseases caused by Aspergillus species, with more detailed discussion on therapy of the most morbid manifestation, invasive aspergillosis.
Marr
Kieren A
KA
Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue, N. D3-100, Seattle, WA 98109, USA. kmarr@fhcrc.org
Patterson
Thomas
T
Denning
David
D
D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D001230:Aspergillus / Q000145:classification / Q000235:genetics / Q000472:pathogenicity; D001232:Aspergillus fumigatus / Q000472:pathogenicity; D019468:Disease Management; D006801:Humans; D016867:Immunocompromised Host; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000276:immunology / Q000628:therapy
D000935:Antifungal Agents