title: Elevated fecal Candida counts in patients with antibiotic-associated diarrhea: role of soluble fecal substances.
abstract: To assess the role of soluble fecal substances in the elevation of fecal Candida counts in patients with antibiotic-associated diarrhea (AAD), we investigated the growth of Candida albicans in vitro in serially diluted stool fluids from patients with AAD and healthy subjects. There were significantly higher Candida albicans counts in stool fluids diluted 1:10 from AAD patients than in healthy subjects and the phosphate-buffered saline growth control, which may be due to reduced soluble Candida inhibitors and increased availability of growth factors and nutrients.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, Karl-Franzens University, Graz, Austria. robert.krause@kfunigraz.ac.at
authors.forename: Robert
authors.initials: R
authors.lastname: Krause
authors.forename: Günter J
authors.initials: GJ
authors.lastname: Krejs
authors.forename: Christoph
authors.initials: C
authors.lastname: Wenisch
authors.forename: Emil C
authors.initials: EC
authors.lastname: Reisinger
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects; D002175:Candida / Q000254:growth & development*; D002177:Candidiasis / Q000209:etiology / Q000382:microbiology; D016022:Case-Control Studies; D003967:Diarrhea / Q000139:chemically induced*; D005243:Feces / Q000382:microbiology*; D006801:Humans; D012995:Solubility
chemical_list: D000900:Anti-Bacterial Agents