Management of congenital lung lesions.
The prenatal diagnostic hallmarks, natural history, and management of congenital cystic adenomatoid malformation of the lung and pulmonary sequestration are reviewed. Large lung tumors may disappear partially on serial prenatal sonography, suggesting that improvement can occur occasionally during fetal life. The fetus with a lung mass but without hydrops has an excellent chance for survival with maternal transport, planned delivery, and postnatal evaluation and surgery. The finding that fetuses with hydrops are at very high risk for fetal or neonatal death has led to successful fetal thoracoamniotic shunt placement or fetal surgical resection.
Adzick
N Scott
NS
Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Flake
Alan W
AW
Crombleholme
Timothy M
TM
D001998:Bronchopulmonary Sequestration / Q000175:diagnosis / Q000601:surgery*; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000175:diagnosis / Q000601:surgery*; D004322:Drainage; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005865:Gestational Age; D006801:Humans; D015160:Hydrops Fetalis / Q000175:diagnosis / Q000601:surgery; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011379:Prognosis; D012307:Risk Factors; D016216:Ultrasonography, Prenatal