title: Steroid injections: effect on pain of spinal origin.
abstract: Pain originating from the spine is a common clinical problem that is often difficult to manage. This chapter considers the evidence supporting the use of corticosteroid injections for pain of spinal origin. Clinical problems considered in this review are radicular pain, zygapophyseal joint pain, discogenic pain and non-specific pain from the cervical, lumbar and thoracic spine. Issues of efficacy and adverse events are considered. No useful data were found concerning the treatment of any type of thoracic pain with corticosteroid injections. In the lumbar spine, there is evidence to support the use of transforaminal injections for radicular pain. Intradiscal and intra-articular injections in both lumbar and cervical spines have not been shown to be effective. Sacroiliitis responds well to intra-articular corticosteroids. There is insufficient evidence to support the use of atlanto-axial or atlanto-occipital joint injections.
authors.affiliation: Department of Rheumatology, Concord Hospital, Concord NSW 2139, Australia.
authors.forename: Les
authors.initials: L
authors.lastname: Barnsley
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D006801:Humans; D007270:Injections, Intra-Articular / Q000379:methods; D007278:Injections, Spinal / Q000379:methods; D007403:Intervertebral Disc / Q000187:drug effects / Q000503:physiopathology; D010146:Pain / Q000188:drug therapy* / Q000209:etiology*; D011843:Radiculopathy / Q000150:complications; D013122:Spinal Diseases / Q000150:complications*; D021801:Zygapophyseal Joint / Q000187:drug effects / Q000503:physiopathology
chemical_list: D000305:Adrenal Cortex Hormones