title: MRI appearance of giant cell tumor of the lateral skull base: a case report.
abstract: The giant cell tumor is considered to be a locally aggressive benign tumor and has a low tendency toward distant metastasis. They are primarily present in the long bone and are rare in the skull. The osteoclast-like giant cells do not demonstrate mitotic activity and contain large numbers of nuclei. Herein, we described a case of giant cell tumor in the temporal lobe. Heterogenous enhancement is shown on CT imaging in solid areas of tumor. The appearance intermediate to high signal intensity on T1-weighted and very low signal intensity on T2-weighted MR imaging were due to the presence of hemosiderin from prior hemorrhage.
authors.affiliation: Department of Radiation Oncology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
authors.forename: Jen-Yang
authors.initials: JY
authors.lastname: Tang
authors.forename: Chien-Kuo
authors.initials: CK
authors.lastname: Wang
authors.forename: Yu-Chieh
authors.initials: YC
authors.lastname: Su
authors.forename: Sheau-Fang
authors.initials: SF
authors.lastname: Yang
authors.forename: Ming-Yii
authors.initials: MY
authors.lastname: Huang
authors.forename: Chih-Jen
authors.initials: CJ
authors.lastname: Huang
mesh_terms: D001707:Biopsy, Needle; D003131:Combined Modality Therapy; D003399:Craniotomy; D005260:Female; D005500:Follow-Up Studies; D005870:Giant Cell Tumors / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D018570:Risk Assessment; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D013701:Temporal Bone; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome