title: [Use of acid-suppressive medications in hospitalized patients].
abstract: BACKGROUND
  The acid-suppressive medications are used frequently in hospitalized patients, but some studies suggests that their are overused, especially in the treatment of stress ulcer prophylaxis in low-risk patients. This research determine the frequency of use and indications of acid-suppressive medications in hospitalized patients in a internal medical service.
  
  
  METHODS
  A at random and retrospective revision of 209 medical records of 661 hospitalized patients during the year 2000 in the V Internal Medical Service of the General University Hospital of Gregorio Marañón (Cantoblanco).
  
  
  BACKGROUND
  Use: any prescription of an acid-suppressive medication, regardless of dosage regimen, in which the patient received at least one dose. Appropriated indication: endoscopical criteria: treatment of active ulcer disease, esophagitis or gastritis. Medical criteria: symptomatic gastroesophageal reflux, dyspepsia, prolonging of previous treatment, as a part of a treatment regimen for H. pylori, relief of dyspepsia caused by nonsteroidal anti-inflammatory drugs, stress ulcer prophylaxis in high risk patients. Inappropriate indication: any other uses were considered not indicated.
  
  
  RESULTS
  Of the 209 patients, a total of 157 (75.1%) received acid-suppressive therapy, average age 76 years old, 89 women (56.7%) and 68 men (43.3%). The admitting diagnoses for the admission were: CHF 34 (21.7%), Pneumonia (16.6%), UTI (15.3%) y COPD 18 (11.5%). The use in hospital ward was 84.7% (133), with inappropriate use 72.2% (96), the cause of prescription "no reason" 52.1% (50), and received proton pump inhibitors 46.9% (45).
  
  
  CONCLUSIONS
  This study show a high frequency of incorrect use of acid-suppressive medications in hospitalized patients.
authors.affiliation: Servicio de Medicina Interna V. Hospital General Universitario Gregorio Marañón, Cantoblanco, Carretera de Colmenar Viejo, km 14,600, 28049 Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Noguerado Asensio
authors.forename: R
authors.initials: R
authors.lastname: Rodríguez Barrientos
authors.forename: P
authors.initials: P
authors.lastname: Zelaya Castro
authors.forename: A
authors.initials: A
authors.lastname: Sánchez Sempere
authors.forename: F
authors.initials: F
authors.lastname: Antuña Blanco
authors.forename: E
authors.initials: E
authors.lastname: Lutz García
authors.forename: R
authors.initials: R
authors.lastname: Quintana de la Cruz
authors.forename: F
authors.initials: F
authors.lastname: Estellés Piera
authors.forename: M S
authors.initials: MS
authors.lastname: Alcázar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D017723:Drug Utilization Review; D004415:Dyspepsia / Q000188:drug therapy; D004941:Esophagitis / Q000188:drug therapy; D005260:Female; D005756:Gastritis / Q000188:drug therapy; D005764:Gastroesophageal Reflux / Q000188:drug therapy; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006760:Hospitalization; D006784:Hospitals, Teaching / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054328:Proton Pump Inhibitors; D012189:Retrospective Studies
chemical_list: D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists; D054328:Proton Pump Inhibitors