title: Protein C deficiency manifesting as an acute myocardial infarction and ischaemic stroke.
abstract: Protein C deficiency is a disorder in the coagulation cascade that results in predominantly venous thromboembolism. However, recent studies have implicated this disorder as a possible contributor to arterial thrombosis, especially myocardial infarction. There are six reported cases of myocardial infarction secondary to protein C deficiency in the literature. This is the first report of myocardial infarction and ischaemic stroke in the same patient as a manifestation of protein C deficiency. The investigation of hypercoagulable state is an essential component of the investigation of young patients with myocardial infarction.
authors.affiliation: Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
authors.forename: I Y
authors.initials: IY
authors.lastname: Tiong
authors.forename: M L
authors.initials: ML
authors.lastname: Alkotob
authors.forename: S
authors.initials: S
authors.lastname: Ghaffari
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000209:etiology*; D023921:Coronary Stenosis / Q000209:etiology; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D009203:Myocardial Infarction / Q000209:etiology*; D020151:Protein C Deficiency / Q000150:complications*; D014057:Tomography, X-Ray Computed