[Coronary thrombosis imaging in humans].
The identification of coronary thrombosis in humans has important prognostic and therapeutic implications. Its recognition calls for invasive techniques: angioscopy, coronarography, and endocoronary ultrasound. Angioscopy allows visualisation of the arterial surface and the detection of thrombus with great sensitivity. Its presence is exclusive to the acute coronary syndromes: 67% in unstable angina, and 75% in myocardial infarction, although it is only present in 27% of cases of stable angina. The relative complexity of its use has led to the abandonment of this technique. Coronarography allows an indirect approach to coronary thrombosis. Certain aspects are evocative such as: intraluminal filling defect, complete occlusion with upstream convexity, ulceration and eccentric type 2 Ambrose classification plaques. As a function of the clinical presentation, the coronarographic views allow a good specificity for the diagnosis of thrombus. The sensitivity is weak, however, compared to angioscopy. Endocoronary ultrasound does not allow identification of fresh thrombus which is not echogenic and does not allow differentiation between older thrombus and lipid plaque. In the future, magnetic resonance imaging could prove interesting in the detection of recent thrombus.
Lablanche
J M
JM
Service de cardiologie B et hémodynamique, hôpital cardiologique, boulevard du Pr-Leclercq, 59037 Lille.
Perrard
G
G
Chmait
A
A
Meurice
T
T
Sudre
A
A
Van Belle
E
E
D017546:Angioscopy / Q000379:methods*; D017023:Coronary Angiography / Q000379:methods*; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D019160:Endosonography / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D012680:Sensitivity and Specificity