title: Bile duct cancer 25 years after choledochoduodenostomy: a case report.
abstract: We describe a 65-year-old man who had undergone choledochoduodenostomy (CDS) for choledocholithiasis 25 years prior to admission to our hospital for cholangitis. Abdominal sonography and computerized tomography (CT) scan revealed a tumor mass at the hilar region with bilateral intrahepatic duct dilatation. Upper gastrointestinal endoscopic examination indicated the site of the CDS. Biopsy was taken from the mucosa of the bile duct, and pathology revealed well-differentiated adenocarcinoma. CT scan and angiography further confirmed unresectable hilar bile duct cancer. Conservative treatment with intra-arterial chemotherapy was arranged. After briefly reviewing the hypothesized pathogenesis and radiographic diagnosis of this rare case, we recommend that chronic cholangitis consequent to CDS should be closely followed for late development of biliary tract malignancy.
authors.affiliation: Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. kkkuo@cc.kmu.edu.tw
authors.forename: Kung-Kai
authors.initials: KK
authors.lastname: Kuo
authors.forename: Pai-Ching
authors.initials: PC
authors.lastname: Sheen
authors.forename: King-Teh
authors.initials: KT
authors.lastname: Lee
authors.forename: Maw-Chang
authors.initials: MC
authors.lastname: Sheen
authors.forename: Shih-Chang
authors.initials: SC
authors.lastname: Chuang
authors.forename: Sen-Ren
authors.initials: SR
authors.lastname: Wang
authors.forename: Wen-Ming
authors.initials: WM
authors.lastname: Wang
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000209:etiology*; D002761:Cholangitis / Q000150:complications; D002768:Choledochostomy / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013997:Time Factors