title: A childhood malignant rhabdoid tumour of the kidney.
abstract: A case report is presented of a malignant rhabdoid tumour occurring in the kidney of a 23-month-old boy. Important differences between this and the conventional Wilms' tumour include the histological demonstration of sheets or cords of large cells resembling myoblasts, a tendency to frequent clinical relapse, and a high mortality rate despite multimodal therapy. In this child, an encouraging initial response to pre-operative chemotherapy, followed by surgical excision and postoperative triple chemotherapy, was not sustained. Recurrence of pulmonary metastases did not respond to further chemotherapy and whole lung irradiation.
authors.affiliation: Departments of Clinical Surgical Sciences, Paraclinical Sciences, Pathology Unit, and Paediatrics, Faculty of Medical Sciences, University of the West Indies, Eric Williams Medical Sciences Complex, Mount Hope, Trinidad and Tobago, West Indies.
authors.forename: T
authors.initials: T
authors.lastname: Anatol
authors.forename: W
authors.initials: W
authors.lastname: Mohammed
authors.forename: J
authors.initials: J
authors.lastname: Nunez
mesh_terms: D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D018335:Rhabdoid Tumor / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy