Ultrastructural localization of 28 kDa glutathione S-transferase in adult Clonorchis sinensis.
Glutathione S-transferase (28GST) with molecular mass of 28 kDa is an antioxidant enzyme abundant in Clonorchis sinensis. In adult C. sinensis, 28GST was localized in tegumental syncytium, cytons, parenchyma, and sperm tails examined by immunoelectron microscopy. C. sinensis 28GST was earlier found to neutralize bioreactive compounds and to be rich in eggs. Accordingly, it is suggested that 28GST plays important roles in phase II defense system and physiological roles in worm fecundity of C. sinensis.
Hong
Sung-Jong
SJ
Department of Parasitology, Chung-Ang University College of Medicine, Seoul 156-756, Korea. hongsj@cau.ac.kr
Yu
Jae-Ran
JR
Kang
Shin-Yong
SY
D000818:Animals; D003004:Clonorchis sinensis / Q000201:enzymology*; D005982:Glutathione Transferase / Q000378:metabolism* / Q000502:physiology; D007150:Immunohistochemistry; D016253:Microscopy, Immunoelectron; D008970:Molecular Weight
D005982:Glutathione Transferase