[Studies on chemical constituents of Cistanche tubulosa (Schenk) R. Wight].
OBJECTIVE
To investigate the chemical constituents of Cistanche tubulosa.


METHODS
The chemical constituents were isolated by solvent extraction together with various chromatographic techniques including preparative HPLC. The structures were elucidated on the basis of chemical evidence and spectral data.


RESULTS
Four iridoid glycosides, one lignan glycoside and one monoterpenoid were isolated from the 95% ethanol extract from the stem of C. tubulosa and identified as adoxosidic acid(I), 8-epiloganic acid(II), geniposidic acid (III), mussaenosidic acid(IV), (+)-syringaresinol-O-beta-D-gluco pyranoside(V) and 8-hydroxygeraniol(VI).


CONCLUSIONS
Compounds I and VI were isolated from the genus of Cistanche for the first time. Compounds III, IV and V were isolated from this plant for the first time.
Song
Z H
ZH
Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Mo
S H
SH
Chen
Y
Y
Tu
P F
PF
Zhao
Y Y
YY
Zheng
J H
JH
D002264:Carboxylic Acids / Q000737:chemistry / Q000302:isolation & purification; D031671:Cistanche / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D057888:Iridoid Glucosides; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification*; D019684:Magnoliopsida / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification
C471578:8-hydroxygeraniol; D002264:Carboxylic Acids; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D057888:Iridoid Glucosides; D039823:Iridoids; D013729:Terpenes; C471577:adoxosidic acid; C058966:geniposidic acid