title: Nitric oxide in liver transplantation: pathobiology and clinical implications.
abstract: The gaseous molecule nitric oxide is involved in a variety of liver transplant-relevant processes, including ischemia-reperfusion injury, acute cellular rejection, and circulatory changes characteristic of advanced liver disease. This review article focuses on new advances relating to the role of nitric oxide in these syndromes with an emphasis on pathobiology and potential clinical implications.
authors.affiliation: GI Research Unit and Advanced Liver Disease Study Group, Department of Medicine, Alfred 2-435, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. shah.vijay@mayo.edu.
authors.forename: Vijay
authors.initials: V
authors.lastname: Shah
authors.forename: Patrick S
authors.initials: PS
authors.lastname: Kamath
mesh_terms: D006084:Graft Rejection / Q000503:physiopathology; D020065:Hepatopulmonary Syndrome / Q000503:physiopathology; D006801:Humans; D016031:Liver Transplantation / Q000502:physiology*; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000502:physiology; D052248:Nitric Oxide Synthase Type I; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III; D015427:Reperfusion Injury / Q000503:physiopathology
chemical_list: D009569:Nitric Oxide; C496320:NOS1 protein, human; C496319:NOS2 protein, human; C496314:NOS3 protein, human; D019001:Nitric Oxide Synthase; D052248:Nitric Oxide Synthase Type I; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III