Synthesis of 13C-labelled, bicyclic mimetics of natural enediynes.
Using a versatile synthesis with 13CH3PPh3I and CH(3)13CO2Et as 13C sources, the first examples of nine-membered chromophores which have been differentially labelled with 13C in their carbocyclic enediyne cores are described.
Das
Parthasarathi
P
Department of Chemistry, Graduate School of Science, Tohoku University, CREST, Japan Science and Technology Corporation (JST), Sendai, Japan.
Mita
Takashi
T
Lear
Martin J
MJ
Hirama
Masahiro
M