title: Use of oxygenated perfluorocarbon toward making every pancreas count.
abstract: The past few years have seen significant advancement in the clinical relevance of intraportal islet cell transplantation for treatment of type 1 diabetes mellitus. The implementation of novel protocols, such as the one developed by the group of Shapiro and collaborators in Edmonton, has revitalized the enthusiasm for cellular transplantation as a treatment for diabetes by improving the success rates and long-term function of islet grafts. Improved results in clinical islet transplantation reported by the groups in Edmonton, Miami, and Minneapolis have re-proposed the much simpler outpatient cell transplant procedure as an alternative to the more risky and technically challenging whole-organ pancreas transplantation.
authors.affiliation: Diabetes Research Institute, University of Miami Medical School, Miami, FL, USA.
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Fraker
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Alejandro
authors.forename: Camillo
authors.initials: C
authors.lastname: Ricordi
mesh_terms: D005466:Fluorocarbons; D006801:Humans; D009926:Organ Preservation / Q000379:methods*; D010100:Oxygen; D016035:Pancreas Transplantation
chemical_list: D005466:Fluorocarbons; D010100:Oxygen