title: Mosaic form (45X/46XX) of Turner's syndrome. A case report.
abstract: BACKGROUND
  Turner's syndrome (TS) is a sex chromosome disorder occurring in 1 in 2,500 female births and in approximately 50 in 100,000 adult females and is characterized by retarded growth, gonadal dysgenesis and infertility. The 45,X/46,XX chromosomal pattern is the most frequent mosaic type of this disease (36%).
  
  
  METHODS
  The mosaic form of TS was diagnosed in a 25-year-old, nulliparous woman whose major symptoms were menstrual irregularity and menorrhagia. She had normal development of secondary sexual characteristics and spontaneous menarche despite a very low amount (7%) of normal cells.
  
  
  CONCLUSIONS
  Dysfunctional uterine bleeding is very uncommon in TS. Mosaic forms of TS may have very few features of TS despite a very low range of normal cells.
authors.affiliation: Departments of Obstetrics and Gynecology and of Medical Biology, Faculty of Medicine, Dokuz Eylul Universitesi, Izmir, Turkey. s.altunyurt@deu.edu.tr
authors.forename: Sabahattin
authors.initials: S
authors.lastname: Altunyurt
authors.forename: Berrin
authors.initials: B
authors.lastname: Acar
authors.forename: Serkan
authors.initials: S
authors.lastname: Guclu
authors.forename: Uğur
authors.initials: U
authors.lastname: Saygili
authors.forename: Meral
authors.initials: M
authors.lastname: Sakizli
mesh_terms: D000328:Adult; D041321:Chromosomes, Human, X; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008572:Menarche; D008595:Menorrhagia / Q000209:etiology* / Q000235:genetics*; D009030:Mosaicism; D012727:Sex Characteristics; D014424:Turner Syndrome / Q000235:genetics*