title: Intermolecular stacking in pyrazolo[3,4-d]pyrimidine-based pentamethylene-linked flexible molecules.
abstract: The crystal structures of 1-[5-[4,6-bis(methylsulfanyl)-2H-pyrazolo[3,4-d]pyrimidin-2-yl]pentyl]-6-methylsulfanyl-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine, C(22)H(29)N(9)S(3), and 6-methylsulfanyl-1-[5-[6-methylsulfanyl-4-(pyrrolidin-1-yl)-2H-pyrazolo[3,4-d]pyrimidin-2-yl]pentyl]-4-(pyrrolidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine, C(25)H(34)N(10)S(2), which differ in having either a pyrrolidine substituent or a methylsulfanyl group, show intermolecular stacking due to aromatic pi-pi interactions between the pyrazolo[3,4-d]pyrimidine rings.
authors.affiliation: Medicinal Chemistry Division, Central Drug Research Institute, Lucknow 226 001, India.
authors.forename: Kamlakar
authors.initials: K
authors.lastname: Avasthi
authors.forename: Sheikh M
authors.initials: SM
authors.lastname: Farooq
authors.forename: Ashish K
authors.initials: AK
authors.lastname: Tewari
authors.forename: Ashoke
authors.initials: A
authors.lastname: Sharon
authors.forename: Prakas R
authors.initials: PR
authors.lastname: Maulik