title: Penetrating corneal transplant with inadvertent corneal button inversion.
abstract: OBJECTIVE
  To report a penetrating corneal transplant in which there was inadvertent inversion of the corneal button.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  A 48-year-old man with lattice corneal dystrophy had a third penetrating keratoplasty in the right eye 3 years after the second procedure and 2 years following renal transplantation.
  
  
  RESULTS
  Histologic examination of the corneal button from the second penetrating keratoplasty disclosed inadvertent corneal graft inversion. Survival epithelium from the donor in the anterior chamber may be explained by the ocular anterior chamber-associated immune deviation or by the patient's systemic cyclosporine A (CsA) treatment after renal transplantation.
  
  
  CONCLUSIONS
  Histologically proven corneal button inversion is a rare cause of corneal graft failure.
authors.affiliation: Department of Pathology, Centre Hospitalier Universitaire de Bordeaux, Hôpital Pellegrin, Bordeaux, France. francois.leger@chu-bordeaux.fr
authors.forename: François
authors.initials: F
authors.lastname: Léger
authors.forename: Bruno
authors.initials: B
authors.lastname: Mortemousque
authors.forename: Delphine
authors.initials: D
authors.lastname: Morel
authors.forename: Isabelle
authors.initials: I
authors.lastname: Riss
authors.forename: Claude
authors.initials: C
authors.lastname: Vital
mesh_terms: D003315:Cornea / Q000473:pathology*; D003317:Corneal Dystrophies, Hereditary / Q000601:surgery*; D006084:Graft Rejection / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007431:Intraoperative Complications / Q000473:pathology*; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D019300:Medical Errors; D008875:Middle Aged; D012086:Reoperation