title: REBASE: restriction enzymes and methyltransferases.
abstract: REBASE contains comprehensive information about restriction enzymes, DNA methyltransferases and related proteins such as nicking enzymes, specificity subunits and control proteins. It contains published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, crystal and sequence data. Homing endonucleases are also included. REBASE contains the most complete and up-to-date information about the methylation sensitivity of restriction endonucleases. In addition, there is extensive information about the known and putative restriction-modification (R-M) systems in more than 100 sequenced bacterial and archaeal genomes. The data is available on the web (http://rebase.neb.com/rebase/rebase.html), through ftp (ftp.neb.com) and as monthly updates via email.
authors.affiliation: New England BioLabs, Inc., 32 Tozer Road, Beverly, MA 01915, USA. roberts@neb.com
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Roberts
authors.forename: Tamas
authors.initials: T
authors.lastname: Vincze
authors.forename: Janos
authors.initials: J
authors.lastname: Posfai
authors.forename: Dana
authors.initials: D
authors.lastname: Macelis
mesh_terms: D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D004262:DNA Restriction Enzymes / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D030562:Databases, Protein; D020745:Genome, Archaeal; D016680:Genome, Bacterial; D013379:Substrate Specificity
chemical_list: D015254:DNA Modification Methylases; D004262:DNA Restriction Enzymes