title: Abnormal pulp calcification in primary molars after fluoride supplementation.
abstract: Forty-five caries-free primary molars from children with continuous fluoride supplementation (n = 28) after birth and from children without fluoride prophylaxis (n = 17) were investigated by light microscopy. The following results were obtained: The prophylaxis group evidenced a special form of calcification consisting of fibrodentin-like hard tissue developing intramurally in the dentin wall especially at the pulp floor and spreading irregularily into the pulp cavity by displacing the degenerating pulp tissue (n = 24). These teeth were ankylosed in the bi- and trifurcation area as well as inside the roots. This kind of hard tissue was not observed in the teeth from untreated children. Only 5 children had greater calcifications attached at the pulp wall. Nevertheless, this difference was statistically significant (p = 0.001) and indicates a relationship between fluoride prophylaxis, the special form of pulp calcification and tooth ankylosis.
authors.affiliation: Department of Orthodontics and Pediatric Dentistry, Klinikum Benjamin Franklin, Freie Universität, Berlin.
authors.forename: Eva-Andrea
authors.initials: EA
authors.lastname: Holtgrave
authors.forename: Werner
authors.initials: W
authors.lastname: Hopfenmüller
authors.forename: Sandra
authors.initials: S
authors.lastname: Ammar
mesh_terms: D000293:Adolescent; D002327:Cariostatic Agents / Q000009:adverse effects*; D016022:Case-Control Studies; D002648:Child; D003784:Dental Pulp Calcification / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D019587:Dietary Supplements / Q000009:adverse effects*; D005260:Female; D005459:Fluorides / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008963:Molar / Q000187:drug effects; D020254:Tooth Ankylosis / Q000209:etiology; D014094:Tooth, Deciduous / Q000187:drug effects
chemical_list: D002327:Cariostatic Agents; D005459:Fluorides