Intratumoral bleeding in meningioma after gamma knife radiosurgery.
OBJECTIVE
The authors evaluated whether gamma knife radiosurgery (GKS) could be a causative factor in intratumoral bleeding in meningiomas.


METHODS
Gamma knife radiosurgery was used in the treatment of 173 meningiomas during a 10-year period. Four patients suffered post-GKS intratumoral hemorrhage. The course in these patients was reviewed. Four of 173 patients suffered an intratumoral hemorrhage during a follow-up period of 1 to 8 years. The risk of intratumoral bleeding after GKS for meningioma was 2.3%. Intracystic hemorrhage occurred in two patients 1 and 5 years, respectively, after radiosurgery. In the other two cases intratumoral bleeding occurred 2 and 8 years, respectively, after radiosurgery. Histological examination in three cases found no specific findings related to the postradiosurgical changes.


CONCLUSIONS
Because the reported risk of spontaneous intratumoral bleeding in meningiomas is 1.3 to 2.7%, the incidence in this series was not unduly high. Radiosurgery itself could not be shown to be a significant factor in the development of the intratumoral bleeding.
Kwon
Yang
Y
Department of Neurological Surgery, Asan Medical Center, Seoul, Korea. ykwon@www.amc.seoul.kr
Ahn
Jae Sung
JS
Jeon
Sang Ryong
SR
Kim
Jeong Hoon
JH
Kim
Chang Jin
CJ
Lee
Jung Kyo
JK
Kwun
Byung Duk
BD
Lee
Do Hee
DH
Kim
Sun Young
SY
D000328:Adult; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology* / Q000473:pathology; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery*; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications; D016634:Radiosurgery / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed