title: Calcification in cystic renal masses: is it important in diagnosis?
abstract: OBJECTIVE
  To determine whether the presence of calcifications in cystic renal masses is important in diagnosis and to suggest an approach to the management of calcified cystic renal masses.
  
  
  METHODS
  Eighty-one cystic renal masses containing calcification in a wall or septum were evaluated by means of review of computed tomographic (CT) images (n = 81), follow-up CT images (n = 28), and results of pathologic examination (n = 40) by the authors in consensus. Images were evaluated for lesion size, amount and morphology of calcification, and any association of calcification with soft-tissue structures. Lesions were categorized according to the Bosniak cyst classification system; the amount of calcification was determined with a subjective grading system. Progression of calcification was qualitatively determined with available follow-up CT scans.
  
  
  RESULTS
  Twenty-one lesions were Bosniak category II (benign) and showed small amounts and thin strands of calcification. Nineteen lesions containing more extensive calcification but no enhancing tissue were category IIF. Follow-up CT results available for 16 of these lesions (average follow-up length, 5 years 8 months) showed no substantial change. The three remaining lesions were proved benign at surgery. Twenty-five lesions were category III; surgical intervention was performed in 21 of these (benign, n = 12; malignant, n = 9). Sixteen lesions that contained obvious areas of enhancing soft tissue were category IV and proved malignant at surgery.
  
  
  CONCLUSIONS
  Calcification in a cystic renal mass is not as important in diagnosis as is the presence of associated enhancing soft-tissue elements. This information should enable a reasonable approach to the management of calcium-containing renal cystic lesions.
authors.affiliation: Department of Radiology, New York University Medical Center, 560 First Ave, Suite HW 202, New York, NY 10016, USA. gary.israel@med.nyu.edu
authors.forename: Gary M
authors.initials: GM
authors.lastname: Israel
authors.forename: Morton A
authors.initials: MA
authors.lastname: Bosniak
mesh_terms: D002114:Calcinosis; D005500:Follow-Up Studies; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000145:classification / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed