Bilateral subthalamic nucleus stimulation improves health-related quality of life in PD.
In order to assess the impact of bilateral subthalamic nucleus (STN) stimulation in PD on quality of life, the PD Quality of Life questionnaire was assessed in 60 consecutive patients with PD before surgery and 12 months after surgery. All aspects of quality of life, including motor (+48%), systemic (+34%), emotional (+29%), and social (+63%) dimensions, significantly improved with long-term STN stimulation.
Lagrange
E
E
Department of Clinical and Biological Neurosciences, Joseph Fourier University, Grenoble, France.
Krack
P
P
Moro
E
E
Ardouin
C
C
Van Blercom
N
N
Chabardes
S
S
Benabid
A L
AL
Pollak
P
P
D000978:Antiparkinson Agents / Q000009:adverse effects; D004599:Electric Stimulation Therapy; D004644:Emotions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007980:Levodopa / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D010300:Parkinson Disease / Q000523:psychology* / Q000601:surgery*; D011788:Quality of Life / Q000523:psychology*; D012919:Social Behavior; D020531:Subthalamic Nucleus / Q000502:physiology*
D000978:Antiparkinson Agents; D007980:Levodopa