title: PRODORIC: prokaryotic database of gene regulation.
abstract: The database PRODORIC aims to systematically organize information on prokaryotic gene expression, and to integrate this information into regulatory networks. The present version focuses on pathogenic bacteria such as Pseudomonas aeruginosa. PRODORIC links data on environmental stimuli with trans-acting transcription factors, cis-acting promoter elements and regulon definition. Interactive graphical representations of operon, gene and promoter structures including regulator-binding sites, transcriptional and translational start sites, supplemented with information on regulatory proteins are available at varying levels of detail. The data collection provided is based on exhaustive analyses of scientific literature and computational sequence prediction. Included within PRODORIC are tools to define and predict regulator binding sites. It is accessible at http://prodoric.tu-bs.de.
authors.affiliation: Institut für Mikrobiologie, Technische Universität Braunschweig, Spielmannstrasse 7, D-38106 Braunschweig, Germany.
authors.forename: Richard
authors.initials: R
authors.lastname: Münch
authors.forename: Karsten
authors.initials: K
authors.lastname: Hiller
authors.forename: Heiko
authors.initials: H
authors.lastname: Barg
authors.forename: Dana
authors.initials: D
authors.lastname: Heldt
authors.forename: Simone
authors.initials: S
authors.lastname: Linz
authors.forename: Edgar
authors.initials: E
authors.lastname: Wingender
authors.forename: Dieter
authors.initials: D
authors.lastname: Jahn
mesh_terms: D001419:Bacteria / Q000235:genetics* / Q000378:metabolism; D001665:Binding Sites; D030541:Databases, Genetic; D040461:Gene Components; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D011387:Prokaryotic Cells / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000235:genetics; D012984:Software; D014157:Transcription Factors / Q000378:metabolism; D014584:User-Computer Interface
chemical_list: D014157:Transcription Factors