title: Extractable/leachable substances from plastic materials used as pharmaceutical product containers/devices.
abstract: A review is provided related to the accumulation of organic and inorganic leachable substances from DEHP-plasticized PVC, polyolefin and various other related pharmaceutical plastic packaging materials. The review considers both the identification of such leachables as well as their reported levels in actual and simulated pharmaceutical products.
authors.affiliation: Baxter Healthcare Corp., Route 120 and Wilson Road, Round Lake, IL 60073, USA. dennis_jenke@baxter.com
authors.forename: Dennis
authors.initials: D
authors.lastname: Jenke
mesh_terms: D004051:Diethylhexyl Phthalate / Q000032:analysis / Q000737:chemistry; D004340:Drug Contamination / Q000517:prevention & control*; D004349:Drug Packaging / Q000592:standards*; D010968:Plasticizers / Q000032:analysis / Q000737:chemistry*; D010969:Plastics / Q000737:chemistry*; D011143:Polyvinyl Chloride / Q000737:chemistry
chemical_list: D010968:Plasticizers; D010969:Plastics; D011143:Polyvinyl Chloride; D004051:Diethylhexyl Phthalate