Toric phakic intraocular lens: European multicenter study.
OBJECTIVE
To evaluate safety, efficacy, predictability, stability, complications, and patient satisfaction after implantation of Artisan toric phakic intraocular lenses (TPIOLs) for the correction of myopia or hyperopia with astigmatism.


METHODS
Prospective, nonrandomized, comparative (self-controlled) multicenter trial.


METHODS
Seventy eyes of 53 patients (mean, 35 years; range, 22-59 years) with preoperative spherical equivalent between +6.50 and -21.25 diopters (D) and cylinder between 1.50 and 7.25 D.


METHODS
Seventy eyes underwent implantation of a TPIOL with an optical zone of 5.0 mm (Artisan, Ophtec, Groningen, The Netherlands). The dioptric power of the intraocular lens was calculated by considering refraction, keratometry, and anterior chamber depth. The follow-up was 6 months in all cases. Lenses were available in powers ranging from +12.0 D to -23.5 D (spherical equivalent) in 0.5-D increments, with additional cylinder from 1.0 D to 7.0 D, also in 0.5-D increments.


METHODS
The main parameters assessed were best spectacle-corrected visual acuity (BSCVA), uncorrected visual acuity (UCVA), refraction, endothelial cell count (ECC), intraocular pressure, slit-lamp biomicroscopy, indirect ophthalmoscopy, subjective complaints, and patient satisfaction.


RESULTS
Eyes were divided into group A, myopia (n = 48), with an average preoperative spherical equivalent of -8.90 +/- 4.52 D, and group B, hyperopia (n = 22), with an average preoperative spherical equivalent of +3.25 +/- 1.98 D. No eyes in either group experienced a loss in BSCVA, and 46 eyes gained 1 or more lines of their preoperative BSCVA. In 62 eyes (88.6%), UCVA was 20/40 or better. There was a significant reduction in spherical errors and astigmatism in all cases after surgery. All eyes of both groups were within +/-1.00 D of target refraction, and 51 eyes (72.9%) were within +/-0.50 D of target refraction. There was a 4.5% mean total loss of ECC during the first 6 months. No serious complications were observed. Overall patient satisfaction was very high.


CONCLUSIONS
Six-month clinical trial results demonstrate that implantation of the Artisan TPIOL safely, predictably, and effectively reduced or eliminated high ametropia and astigmatism with one procedure. The refractive effect was stable at 6 months after surgery.
Dick
H Burkhard
HB
Department of Ophthalmology, University of Mainz, Mainz, Germany. bdick@mail.uni-mainz.de
Alió
Jorge
J
Bianchetti
Marco
M
Budo
Camille
C
Christiaans
Bern Jurriën
BJ
El-Danasoury
M Alaa
MA
Güell
José L
JL
Krumeich
Jörg
J
Landesz
Monika
M
Loureiro
Fransico
F
Luyten
Gregorius P M
GP
Marinho
Antonio
A
Rahhal
Mohamed Saleh
MS
Schwenn
Oliver
O
Spirig
Raimund
R
Thomann
Urs
U
Venter
Jan
J
D000328:Adult; D001251:Astigmatism / Q000601:surgery*; D002452:Cell Count; D004728:Endothelium, Corneal / Q000166:cytology; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000601:surgery*; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular; D007908:Lens, Crystalline / Q000502:physiology*; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D012029:Refraction, Ocular; D012449:Safety; D014792:Visual Acuity