Characterization of the first extended-spectrum beta-lactamase-producing Salmonella isolate identified in Canada.
A single Salmonella enterica serovar Typhimurium isolate with an UT2 phage type producing an extended-spectrum beta-lactamase (ESBL) was identified in Canada in 2000. The isolate harbored two plasmids, one containing a bla(TEM-1) gene and the other containing a bla(SHV-2a) gene. The ESBL gene was located on a 70-kb transferable plasmid which also carried tetracycline and trimethoprim resistance elements.
Mulvey
Michael R
MR
Nosocomial Infections, National Microbiology Laboratory, Health Canada, Winnipeg, Manitoba, Canada. Michael_Mulvey@hc-sc.gc.ca
Soule
Geoff
G
Boyd
David
D
Demczuk
Walter
W
Ahmed
Rafiq
R
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002170:Canada; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics*; D012475:Salmonella / Q000187:drug effects / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D013753:Tetracycline Resistance; D014296:Trimethoprim Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases