title: Effects of conjugated linoleic acid (CLA) on immune responses, body composition and stearoyl-CoA desaturase.
abstract: Conjugated linoleic acid (CLA) has shown a wide range of biologically beneficial effects; reduction of incidence and severity of animal carcinogenesis, reduction of the adverse effects of immune stimulation, reduction of severity of atherosclerosis, growth promotion in young rats, and modulation of stearoyl-CoA desaturase (SCD). One of the most interesting aspects of CLA is its ability to reduce body fat while enhancing lean body mass which is associated with the trans-10,cis-12 isomer of CLA. The effects of CLA are unique characteristics that have not been observed with other polyunsaturated fatty acids. In this review, we will focus on the effects of CLA on immune responses, body compositional changes and stearoyl-CoA desaturase.
authors.affiliation: Department of Biochemistry, Food Research Institute, University of Wisconsin-Madison, WI, USA.
authors.forename: James M
authors.initials: JM
authors.lastname: Ntambi
authors.forename: Youngjin
authors.initials: Y
authors.lastname: Choi
authors.forename: Yeonhwa
authors.initials: Y
authors.lastname: Park
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Peters
authors.forename: Michael W
authors.initials: MW
authors.lastname: Pariza
mesh_terms: D000818:Animals; D001823:Body Composition / Q000187:drug effects*; D006801:Humans; D007107:Immune System / Q000187:drug effects*; D008041:Linoleic Acids / Q000276:immunology / Q000494:pharmacology*; D013230:Stearoyl-CoA Desaturase / Q000187:drug effects* / Q000378:metabolism
chemical_list: D008041:Linoleic Acids; D013230:Stearoyl-CoA Desaturase