Parkinsonism as a manifestation of multiple sclerosis.
We describe a 48-year-old patient, with a diagnosis of relapsing-remitting multiple sclerosis, who presented to our service with a parkinsonian syndrome that markedly improved after corticosteroid treatment. To the best of our knowledge, only 12 cases of parkinsonism have been reported from 1970 to the present, of which only 8 seemed secondary to MS, i.e., those presenting conclusive imaging evidence or unequivocal response to corticosteroids.
Folgar
Silvia
S
Movement Disorders and Parkinson's Disease Program, Institute of Neurosciences, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
Gatto
Emilia Mabel
EM
Raina
Gabriela
G
Micheli
Federico
F
D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000175:diagnosis* / Q000188:drug therapy; D009460:Neurologic Examination / Q000187:drug effects; D020734:Parkinsonian Disorders / Q000175:diagnosis* / Q000188:drug therapy
D008775:Methylprednisolone