Human cutaneous leishmaniasis due to Leishmania infantum in the Sidi Bourouis focus (Northern Tunisia): epidemiological study and isoenzymatic characterization of the parasites.
The authors report an increase of the number of case of cutaneous leishmaniasis in the Sidi Bourouis region community of Siliana Governorate (Tunisia), with 38 cases diagnosed in 6 months (1st November 2000-30th April 2001), contrary to its usual sporadic character. The isoenzymatic identification of 15 isolated strains emphasizes the role of the Leishmania infantum zymodeme MON-1 as an important factor in the genesis of the sporadic cutaneous leishmaniasis of Northern Tunisia. In fact it was isolated in 6 cases while L. infantum MON-24, the usual agent was isolated in 9 cases.
Belhadj
S
S
Laboratoire de Parasitologie-Mycologie, Hôpital La Rabta, 1007 Tunis, Tunisia. emna.chaker@rns.tn
Pratlong
F
F
Hammami
M
M
Kallel
K
K
Dedet
J P
JP
Chaker
E
E
D000368:Aged; D000818:Animals; D002478:Cells, Cultured; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000032:analysis*; D018314:Leishmania infantum / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology*; D008297:Male; D008536:Meglumine / Q000494:pharmacology / Q000627:therapeutic use; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds / Q000494:pharmacology / Q000627:therapeutic use; D014416:Tunisia / Q000453:epidemiology
D007527:Isoenzymes; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate