title: [Linker histones: conformational changes and the role in the structural organization of chromatin].
abstract: Histones, linker histones of the H1 family, their postsyntetic modifications, DNA-histone H1 interaction are reviewed. A question of protein change in spermatogenesis at the formation of inactive nucleus with high degree of DNA density is considered. Special attention was paid to sperm-specific histones of the H1 family of sperm cells. Their role in organization of high-order chromatin structure of sperm cells is discussed. Also, results of different studies on the structural organization of chromatin (nucleosomes, 30-nm fibers, chromatin loops and metaphase chromosomes) are discussed.
authors.affiliation: Institute of Cytology RAS, St. Petersburg. chikhir@hotmail.com
authors.forename: E V
authors.initials: EV
authors.lastname: Chikhirzhina
authors.forename: V I
authors.initials: VI
authors.lastname: Vorob'ev
mesh_terms: D000818:Animals; D002843:Chromatin / Q000737:chemistry* / Q000378:metabolism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D006657:Histones / Q000737:chemistry* / Q000378:metabolism; D008297:Male; D011487:Protein Conformation; D013094:Spermatozoa / Q000648:ultrastructure
chemical_list: D002843:Chromatin; D006657:Histones; D004247:DNA