title: [Histomorphologic characteristics of osteosarcoma].
abstract: We reviewed the results examinations, made on 16 patients treated for osteosarcoma at Orthopaedic end Traumatology Clinic of University Clinical Center in Tuzla, over a ten-year period. Clinical aspects were studied using medical records (patient, scharts, historyes, radiographs). Quantification of tissue and cellular quality structural changes in the focus of bone destruction were done using a morphometrical or stereological method. The volume density (Vv) of the stroma mass and of the necrotical bone rafters, as well as the numeric density (Nv) of cells were determined on the pathohistologic transsections. The results suggest that in the bone destruction focus predominate mononuclears and giant cells of osteoclast type, and practically there is no osteogenesis reparatory cells.
authors.affiliation: Zavod za histologiju i embriologiju, Medicinski fakultet Univerziteta u Tuzli.
authors.forename: Zlata
authors.initials: Z
authors.lastname: Zigić
authors.forename: Bono
authors.initials: B
authors.lastname: Marković
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology*; D001842:Bone and Bones / Q000473:pathology; D002648:Child; D006801:Humans; D008875:Middle Aged; D012516:Osteosarcoma / Q000473:pathology*