title: [Senecio jacobaea: deceiving beauty. Senecio jacobaea poisoning].
abstract: In a cattle herd problems were noticed during 1.5 years, characterised by emaciation and loss of milk production with lower fat- and protein%, tenesmus, central nervous symptoms (aggression, circling and blindness), diarrhoea, eczema solare and death. Clinical, laboratory and post mortem examinations did not reveal a specific cause at first. An intoxication was suspected based on the clinical symptoms, the course of the disease in sick animals and severe liver cirrhosis found in a sudden death cow: The animals were fed grassilage derived from an air force base on which an overwhelming amount of tansy ragwort (Senecio jacobaea) was present. On subsequent microscopic examination of the livers of 11 slaughtered clinically healthy animals all of these showed fibrosis in varying extension. Cirrhosis and fibrosis of the liver and the clinical symptoms are all features of chronic pyrrolyzidine alkaloidosis. Tansy ragwort poisoning has not been diagnosed in the Netherlands for years. The rise in cases is due to more extensive use of land.
authors.affiliation: Gezondheidsdienst voor Dieren, Postbus 9, 7400 AA Deventer. j.vos@gdvdieren.nl
authors.forename: J H
authors.initials: JH
authors.lastname: Vos
authors.forename: A A J
authors.initials: AA
authors.lastname: Geerts
authors.forename: J W
authors.initials: JW
authors.lastname: Borgers
authors.forename: M H
authors.initials: MH
authors.lastname: Mars
authors.forename: J A M
authors.initials: JA
authors.lastname: Muskens
authors.forename: L A
authors.initials: LA
authors.lastname: van Wuijckhuise-Sjouke
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D003937:Diagnosis, Differential; D005260:Female; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D010939:Plant Poisoning / Q000473:pathology / Q000517:prevention & control / Q000662:veterinary*; D011763:Pyrrolizidine Alkaloids / Q000506:poisoning; D012674:Senecio / Q000506:poisoning*; D012820:Silage / Q000506:poisoning*
chemical_list: D011763:Pyrrolizidine Alkaloids