Bilateral retinal hemorrhages in an 18-year-old woman.
A previously healthy 18-year-old woman presented with sudden onset of central blurred vision in the right eye. Fundoscopic examination showed retinal venous tortuosity, several flame-shaped hemorrhages bilaterally, and a subhyaloid hemorrhage in the right fovea. Laboratory evaluation and subsequent bone marrow biopsy were consistent with the diagnosis of acute lymphoblastic leukemia. The retinal findings had cleared almost completely by three weeks after initiation of chemotherapy.
Abdul-Rahim
Aziz S
AS
Department of Ophthalmology and Visual Sciences, Texas Tech University Health Sciences Center, 3601 4th Street, Lubbock, TX 79430, USA.
Brown
Sandra M
SM
Shami
Michel J
MJ
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003630:Daunorubicin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010211:Papilledema / Q000209:etiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D012166:Retinal Hemorrhage / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome; D014750:Vincristine / Q000627:therapeutic use; D014792:Visual Acuity
D014750:Vincristine; D011239:Prednisolone; D003630:Daunorubicin