[Study on the preparation of baicalin complex with phospholipid].
OBJECTIVE
To choose the optimization conditions for the formation of baicalin complex with phospholipid.


METHODS
A reasonable criterion of accurate evaluation was established, by which such factors as temperature, the ratio of baicalin to phospholipid and the concentration of reactants were examined and the orthographic design was used.


RESULTS
The best conditions were obtained through statistical analysis and proof test.


CONCLUSIONS
The formation of baicalin complex with phospholipid was greatly influenced by the solvent, concentration and reactant ratio.
Wu
J M
JM
Shenyang Pharmaceutical University, Shenyang 110015, Liaoning, China.
Chen
D W
DW
Liu
Y L
YL
D004337:Drug Carriers; D005419:Flavonoids / Q000008:administration & dosage*; D010743:Phospholipids; D013678:Technology, Pharmaceutical / Q000379:methods*
D004337:Drug Carriers; D005419:Flavonoids; D010743:Phospholipids; C038044:baicalin