title: Percutaneous management of occlusive arterial disease associated with vasculitis: a single center experience.
abstract: The purpose of this study was to evaluate the safety and effectiveness of percutaneous transluminal angioplasty for occlusive arterial disease associated with vasculitis. Eleven patients (10 women, 1 man; ages 35-82 years) with the diagnosis of vasculitis of the large vessels underwent interventional treatment during intraarterial angiography. The causes included giant cell arteritis (n = 8) and Takayasu arteritis (n = 3). Thirty-three occlusive lesions (including brachiocephalic and renal arteries, and arteries of upper and lower extremities) were treated with balloon angioplasty and/or stent placement. Follow-up included clinical examination, angiography, and color duplex ultrasound. Technical success was 100% (25/25) for stenoses and 50% (4/8) for occlusive lesions, representing all lesions combined from different anatomic locations. Dissection (n = 3) and arterial rupture with retroperitoneal hematoma (n = 1) was found in three patients. During follow-up (mean 12 months), restenoses (n = 8) and re-restenoses (n = 1) occurred in 8 vascular areas. Three of these lesions were treated with repeated PTA (n = 4). The cumulative primary clinical success rate was 67.6%, cumulative secondary success rate 74.4%, and cumulative tertiary success rate 75.9%. Interventional therapy in systemic vasculitis provides promising results in technical success rates and followup. Angioplasty may result in arterial injury, but the rate of complications is low.
authors.affiliation: Department of Radiology, Christian-Albrechts-University of Kiel, Kiel, Germany. mboth@rad.uni-kiel.de
authors.forename: M
authors.initials: M
authors.lastname: Both
authors.forename: T
authors.initials: T
authors.lastname: Jahnke
authors.forename: E
authors.initials: E
authors.lastname: Reinhold-Keller
authors.forename: M
authors.initials: M
authors.lastname: Reuter
authors.forename: J
authors.initials: J
authors.lastname: Grimm
authors.forename: J
authors.initials: J
authors.lastname: Biederer
authors.forename: J
authors.initials: J
authors.lastname: Brossmann
authors.forename: W L
authors.initials: WL
authors.lastname: Gross
authors.forename: M
authors.initials: M
authors.lastname: Heller
authors.forename: S
authors.initials: S
authors.lastname: Mueller-Huelsbeck
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000800:Angioplasty, Balloon; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D015607:Stents; D016896:Treatment Outcome; D014657:Vasculitis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*