title: Exploring methods of wound debridement.
abstract: Dead tissue, in the form of slough and necrosis, can, if present in a wound, delay healing and promote infection. Debridement describes any method by which such materials are removed and, as a consequence, the potential to achieve wound healing enhanced. In this article, the first of two, the author discusses the history of debridement, cell death, the nature of necrotic tissue and a variety of debridement techniques. All methods of debridement have associated risks and benefits and while this article examines its clinical application there are also legal and professional issues to consider particularly in relation to conservative sharp debridement. These issues will be addressed in the second article.
authors.affiliation: East London Wound Healing Centre, Tower Hamlets Primary Care Trust and Great Ormond Street Hospital, London, UK. obrienm@blueyonder.co.uk
authors.forename: Mark
authors.initials: M
authors.lastname: O'Brien
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D017209:Apoptosis; D001458:Bandages; D001881:Borates / Q000627:therapeutic use; D003646:Debridement / Q000009:adverse effects / Q000379:methods* / Q000451:nursing; D006801:Humans; D006861:Hydrogen Peroxide / Q000627:therapeutic use; D009336:Necrosis; D011206:Povidone-Iodine / Q000627:therapeutic use; D012307:Risk Factors; D012973:Sodium Hypochlorite / Q000627:therapeutic use; D016896:Treatment Outcome; D014945:Wound Healing; D014947:Wounds and Injuries / Q000209:etiology / Q000473:pathology / Q000628:therapy*
chemical_list: D000891:Anti-Infective Agents, Local; D001881:Borates; C024611:Eusol; D011206:Povidone-Iodine; D006861:Hydrogen Peroxide; D012973:Sodium Hypochlorite