Atypical lipomatous tumour (lipoma-like well-differentiated liposarcoma) arising in a pulmonary hamartoma and clinically presenting with pneumothorax.
We document an uncommon variant of pulmonary hamartoma (PH), discovered in the left upper lobe of a 60-year-old man after an episode of pneumothorax, a unique clinical presentation for such an occurrence. The tumour showed a prominent leaf-like pattern and was mainly composed of mature fat with adipocytes of different size and scattered throughout lipoblasts and floret-like cells. A lobectomy was performed and more than 7 years after surgery the patient's course is still uneventful. This case represents an exceedingly rare example of an histologically malignant change in PH and bears a close clinicopathologic resemblance to atypical lipomatous tumours of soft tissues.
Rossi
Giulio
G
Department of Pathological Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Via del Pozzo, 71-41100, Modena, Italy. rossi.giulio@unimo.it
Cavazza
Alberto
A
Valli
Riccardo
R
Torricelli
Pietro
P
Richeldi
Luca
L
Rivasi
Francesco
F
Brambilla
Elisabeth
E
D006222:Hamartoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008080:Liposarcoma / Q000150:complications* / Q000473:pathology*; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011030:Pneumothorax / Q000150:complications* / Q000473:pathology; D016896:Treatment Outcome