Catalytic enantioselective epoxidation of homoallylic alcohols by chiral zirconium complexes.
Catalytic enantioselective epoxidation of homoallylic alcohols using Zr(Ot-Bu)(4) and tartrate ester (or tartramide) has been developed. In the Zr(Ot-Bu)(4)/diisopropyl tartrate-catalyzed epoxidation, the reverse of the enantiofacial preference was observed, depending on the Zr/ligand ratios of 1:1 or 1:2. [reaction--see text]
Okachi
Takahiro
T
Department of Chemistry, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro, Tokyo 153-8902, Japan.
Murai
Norio
N
Onaka
Makoto
M