title: Statistical evaluation and comparison of comet assay results.
abstract: A method of critical evaluation of comet assay test results is proposed. This method is based on representing frequency histograms of tail moments and %DNA in the tail with the use of the unsymmetrical Weibull distribution. The distribution is fully characterized by two parameters: shape (alpha) and scale (beta). Coefficients of variation and confidence intervals of the parameters have been determined.
authors.affiliation: Drug Institute, 30/34 Chelmska Street, 00-725 Warsaw, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Ejchart
authors.forename: Nina
authors.initials: N
authors.lastname: Sadlej-Sosnowska
mesh_terms: D001761:Bleomycin / Q000494:pharmacology; D002478:Cells, Cultured; D020552:Comet Assay / Q000379:methods*; D004249:DNA Damage / Q000187:drug effects; D003627:Data Interpretation, Statistical; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D016008:Statistical Distributions
chemical_list: D001761:Bleomycin