title: Alternate stranded triplex formation of chimeric DNA composed of tandem alpha- and beta-anomeric strands.
abstract: A chimeric oligoDNA composed of a natural beta-anomeric oligonucleotide portion and an unnatural alpha-anomeric oligonucleotide portion forms an alternate stranded triplex possessing enhanced thermal stability compared to the triplexes composed of the parental oligomers.
authors.affiliation: Department of Chemistry, Faculty of Engineering, Gunma University, 1-5-1 Tenjin-cho, Kiryu 376-8515, Japan. sinozuka@chem.gunma-u.ac-jp
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shinozuka
authors.forename: Noritake
authors.initials: N
authors.lastname: Matsumoto
authors.forename: Hideo
authors.initials: H
authors.lastname: Suzuki
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Moriguchi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Sawai
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D009690:Nucleic Acid Conformation
chemical_list: C051802:triplex DNA; D004247:DNA