Chromosome mapping of MHC class I in rainbow trout (Oncorhynchus mykiss).
The major histocompatibility complex (MHC) is well-studied in mammals. Much research has addressed the genomic organisation of MHC genes and it is well established that human MHC class I genes are located on chromosome 6. However, information on the organisation of the MHC complex in rainbow trout is only beginning to become available. In the present study it was determined that rainbow trout MHC class I sequences are located on chromosome 18. This is the first reported use of fluorescence in situ hybridisation (FISH) to identify the chromosomal location of genes involved in the immune system of fish.
Fujiwara
Atushi
A
Department of Aquatic Biosciences, Tokyo University of Fisheries, Konan 4, Minato-ku, Tokyo, 108-8477, Japan.
Kiryu
Ikunari
I
Dijkstra
Johannes Martinus
JM
Yoshiura
Yasutoshi
Y
Nishida-Umehara
Chizuko
C
Ototake
Mitsuru
M
D000818:Animals; D002874:Chromosome Mapping; D019143:Evolution, Molecular; D005805:Genes, MHC Class I / Q000235:genetics*; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence / Q000662:veterinary; D017686:Oncorhynchus mykiss / Q000235:genetics* / Q000276:immunology
D015395:Histocompatibility Antigens Class I