title: Effect of dried fruits of Carica papaya Linn on hepatotoxicity.
abstract: Ethanol and aqueous extracts of Carica papaya has been evaluated for its anti hepatotoxic activity. The ethanol and aqueous extracts of Carica papaya showed remarkable hepatoprotective activity against CCl(4) induced hepatotoxicity. The activity was evaluated by using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase, total bilirubin and gamma glutamate transpeptidase (GGTP). The histopathological changes of liver sample was compared with respect to control.
authors.affiliation: Department of Pharmacology, Vinayaka Mission's College of Pharmacy, Salem, Tamil Nadu, India. rajkapoorb@yahoo.co.in
authors.forename: Balasubramanian
authors.initials: B
authors.lastname: Rajkapoor
authors.forename: Balasundaram
authors.initials: B
authors.lastname: Jayakar
authors.forename: Subramanian
authors.initials: S
authors.lastname: Kavimani
authors.forename: Narayanan
authors.initials: N
authors.lastname: Murugesh
mesh_terms: D000818:Animals; D002251:Carbon Tetrachloride / Q000633:toxicity; D029441:Carica; D005519:Food Preservation; D005638:Fruit; D007928:Lethal Dose 50; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D051381:Rats
chemical_list: D010936:Plant Extracts; D002251:Carbon Tetrachloride