The effect of hormonal factors on the hearing organ in women, after surgical castration. Preliminary report.
BACKGROUND
Estrogens have not only direct and beneficial effect on relaxation of the arteries increasing the blood flow in the blood vessels, but also their level of secretion has considerable effect on synthesis of acetylcholine a neurotransmitter indispensable for appropriate functioning of the hearing organ. The aim of this study is analysis of the effect of hormones on the hearing organ in women who underwent surgical castration.


METHODS
The study included 40 females, aged between 32 55 years who had undergone an operative treatment mainly because of uterine myoma. A group of 50 women aged between 32 50 years with appropriate hormone level comprised the control group.


METHODS
Each woman investigated underwent the following examinations: gynaecological, otolaryngological and laboratory tests, such as: evaluation of levels of estradiol (E) and folliculin stimulating hormone (FSH). The assessment of hearing was carried out using tone and speech audiometry, tympanometry, test registration of auditory brain stem responses (ABR) and otoacoustic emissions (EOAE). The examinations mentioned above are performed in women as initial examinations before surgical treatment and as follow-up examinations 1, 3 and 12 months after the surgery.


RESULTS
The results presented in this paper include initial examinations and follow-ups 3 months after the surgical treatment taking into consideration the correlation with the results of laboratory tests and the results obtained in the control group.
Reron
A
A
Department of Obstetrics and Gynaecology, Jagiellonian University, Kopernika 23, PL-23-501 Kracow, Poland.
Reron
E
E
Strek
P
P
Trojnar-Podlesny
M
M
D000328:Adult; D001309:Auditory Threshold; D003692:Delayed-Action Preparations / Q000008:administration & dosage; D004958:Estradiol / Q000008:administration & dosage / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D005500:Follow-Up Studies; D034381:Hearing Loss / Q000175:diagnosis* / Q000209:etiology; D006320:Hearing Tests; D020249:Hormone Replacement Therapy; D006801:Humans; D008875:Middle Aged; D017084:Otoacoustic Emissions, Spontaneous; D010052:Ovariectomy / Q000009:adverse effects
D003692:Delayed-Action Preparations; D004958:Estradiol; D005640:Follicle Stimulating Hormone