[Evaluation of blood flow velocity and cerebrovascular reactivity in patient with posterior circulation stroke].
The aim of our study was to determine the type of blood flow disturbances and cerebrovascular reactivity of major anterior and posterior circulation cerebral vessels in patients with posterior stroke (POCI). The examined group consisted of 17 patients, mean age 57 +/- 12 yr, with posterior circulation infarct. Neurological examination, brain CT and Doppler examination including evaluation of BFV and CVR of MCA, PCA and VA was performed in each patient. Doppler examination was done using Pioneer TC 2020 and capnograph Tidal Wave sp Novametrix.


RESULTS
BFV of ICA's, MCA's, ACA's and PCA's were diminished while BFV of VA's were significantly diminished in the examined patients compared to healthy controls. CVR of MCA in posterior circulation stroke patients was significantly lower compared to controls. CVR of PCA and VA was significantly lower compared to CVR of MCA in patients with posterior circulation stroke.


CONCLUSIONS
Impairment of CVR, especially in posterior circulation, plays an important role in posterior circulation stroke pathogenesis.
Pierzchała
Krystyna
K
Kliniki Neurologii w Zabrzu.
Kwieciński
Janusz
J
Kapustecki
Janusz
J
D000328:Adult; D000368:Aged; D020771:Anterior Cerebral Artery / Q000503:physiopathology; D001783:Blood Flow Velocity; D001921:Brain / Q000098:blood supply* / Q000503:physiopathology; D002343:Carotid Artery, Internal / Q000503:physiopathology; D016022:Case-Control Studies; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D020762:Infarction, Posterior Cerebral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000503:physiopathology; D020769:Posterior Cerebral Artery / Q000503:physiopathology; D012016:Reference Values; D018570:Risk Assessment; D017585:Ultrasonography, Doppler, Transcranial; D014711:Vertebral Artery / Q000503:physiopathology