[Study on anticancer activity of Syngnathus in vitro].
OBJECTIVE
To study the anticancer activity of Syngnathus in vitro.


METHODS
Observing the influence of different extracts from Syngnathus on growth of different cancer cell strains by MTT method.


RESULTS
It has been found out that the fat-soluble nonsaponified extract from Temminck et Schlegel and the alcoholic extract from Syngnathus acus have cytotoxic activities. The nonsaponified extract from Temminck et Schlegel can inhibit the growth of cancer cell strains KB, Hela, PAA, K562, and Bcap37, and the alcoholic extract from Syngnathus acus can inhibit the growth of cancer cell strin KB, But Bloch shows no apparent anticancer activity.


CONCLUSIONS
Syngnathus has promising prospects as an anticancer Chinese medicine.
Li
S M
SM
School of Pharmacy, Zhejiang University, Hangzhou 310031, Zhejiang, China.
Wu
X D
XD
Zeng
S
S
Luan
L J
LJ
Shao
Q
Q
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D005399:Fishes; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D020014:K562 Cells / Q000187:drug effects; D008419:Materia Medica / Q000494:pharmacology*; D000091402:Prohibitins; D013778:Tetrazolium Salts; D013844:Thiazoles; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D008419:Materia Medica; C000717331:PHB2 protein, human; D000091402:Prohibitins; D013778:Tetrazolium Salts; D013844:Thiazoles; C022616:thiazolyl blue