title: The science of bone cement: a historical review.
abstract: The use of PMMA bone cement has been a key factor in the advent of joint replacement as a surgical option. Despite revolutionary changes in joint replacement technology for the treatment of hip and knee arthritis, the use of PMMA bone cement in its intraoperative application has not significantly changed since Harris' description of third generation cement technique. Future answers to questions regarding cemented implant longevity may lie in the further improvement of existing PMMA technology and standardization of the manufacturing of PMMA bone cement intraoperatively.
authors.affiliation: Department of Orthopedic Surgery, State University of New York at Stony Brook, USA.
authors.forename: Frank R
authors.initials: FR
authors.lastname: DiMaio
mesh_terms: D019643:Arthroplasty, Replacement / Q000266:history / Q000379:methods*; D001843:Bone Cements / Q000266:history / Q000627:therapeutic use*; D002484:Cementation / Q000266:history / Q000379:methods*; D049673:History, 20th Century; D006801:Humans; D019904:Polymethyl Methacrylate / Q000266:history / Q000627:therapeutic use*
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate