Exploring plant genomes by RNA-induced gene silencing.
The nucleotide sequences of several animal, plant and bacterial genomes are now known, but the functions of many of the proteins that they are predicted to encode remain unclear. RNA interference is a gene-silencing technology that is being used successfully to investigate gene function in several organisms--for example, Caenorhabditis elegans. We discuss here that RNA-induced gene silencing approaches are also likely to be effective for investigating plant gene function in a high-throughput, genome-wide manner.
Waterhouse
Peter M
PM
CSIRO Plant Industry, Canberra, Australian Capital Territory 2601, Australia. peter.waterhouse@csiro.au
Helliwell
Christopher A
CA
D005544:Forecasting; D020868:Gene Silencing; D005822:Genetic Vectors / Q000378:metabolism; D018745:Genome, Plant; D010942:Plant Viruses / Q000378:metabolism; D010944:Plants / Q000235:genetics* / Q000821:virology; D012313:RNA / Q000378:metabolism*; D034622:RNA Interference; D014158:Transcription, Genetic
D012313:RNA