title: PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data.
abstract: PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently completed P. falciparum genome sequence and annotation, as well as draft sequence and annotation emerging from other Plasmodium sequencing projects. PlasmoDB currently houses information from five parasite species and provides tools for intra- and inter-species comparisons. Sequence information is integrated with other genomic-scale data emerging from the Plasmodium research community, including gene expression analysis from EST, SAGE and microarray projects and proteomics studies. The relational schema used to build PlasmoDB, GUS (Genomics Unified Schema) employs a highly structured format to accommodate the diverse data types generated by sequence and expression projects. A variety of tools allow researchers to formulate complex, biologically-based, queries of the database. A stand-alone version of the database is also available on CD-ROM (P. falciparum GenePlot), facilitating access to the data in situations where internet access is difficult (e.g. by malaria researchers working in the field). The goal of PlasmoDB is to facilitate utilization of the vast quantities of genomic-scale data produced by the global malaria research community. The software used to develop PlasmoDB has been used to create a second Apicomplexan parasite genome database, ToxoDB (http://ToxoDB.org).
authors.affiliation: Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: Amit
authors.initials: A
authors.lastname: Bahl
authors.forename: Brian
authors.initials: B
authors.lastname: Brunk
authors.forename: Jonathan
authors.initials: J
authors.lastname: Crabtree
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Fraunholz
authors.forename: Bindu
authors.initials: B
authors.lastname: Gajria
authors.forename: Gregory R
authors.initials: GR
authors.lastname: Grant
authors.forename: Hagai
authors.initials: H
authors.lastname: Ginsburg
authors.forename: Dinesh
authors.initials: D
authors.lastname: Gupta
authors.forename: Jessica C
authors.initials: JC
authors.lastname: Kissinger
authors.forename: Philip
authors.initials: P
authors.lastname: Labo
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Mailman
authors.forename: Arthur J
authors.initials: AJ
authors.lastname: Milgram
authors.forename: David S
authors.initials: DS
authors.lastname: Pearson
authors.forename: David S
authors.initials: DS
authors.lastname: Roos
authors.forename: Jonathan
authors.initials: J
authors.lastname: Schug
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Stoeckert
authors.forename: Patricia
authors.initials: P
authors.lastname: Whetzel
mesh_terms: D000818:Animals; D019295:Computational Biology; D030541:Databases, Genetic; D015870:Gene Expression; D018503:Genome, Protozoan; D016247:Information Storage and Retrieval; D010961:Plasmodium / Q000235:genetics; D010963:Plasmodium falciparum / Q000235:genetics* / Q000378:metabolism; D040901:Proteomics; D012984:Software