[Effect of bacteriophage on the lipid peroxidation process and antioxidant protective enzymes in experimental uveitis].
Experimental uveitis features distinct hyperlipoperoxidation in damaged eye tissues, blood serum and the liver. The activity of antioxidant defense (AOD) enzymes decreases in tissues and blood of experimental animals whereas catalase compensatorily activates in hepatic tissue. Experimental therapy of uveitis with gentamycin and bacteriophage results in reducing hyperlipoperoxidation, increased activity of AOD enzymes but no complete normalization is observed. This manifested in preservation of inflammations to a certain degree.
Karimova
M Kh
MKh
Bakhritdinova
F A
FA
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001435:Bacteriophages; D002374:Catalase / Q000378:metabolism*; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D011817:Rabbits; D013482:Superoxide Dismutase / Q000378:metabolism*; D014605:Uveitis / Q000201:enzymology / Q000378:metabolism / Q000628:therapy*
D000975:Antioxidants; D008315:Malondialdehyde; D002374:Catalase; D013482:Superoxide Dismutase