title: Non-obese hyperlipidemic Asian northern Indian males have adverse anthropometric profile.
abstract: OBJECTIVE
  Hyperlipidemia is commonly ascribed to obesity. We studied the association of anthropometric profile and nutrient intake with hyperlipidemia in non-obese Asian Indian males.
  
  
  RESULTS
  In a case-control study, non-diabetic, non-obese males with body mass index (BMI) < 25 Kg/m2 having primary hyperlipidemia (n = 50) were compared with healthy normolipidemic males (BMI < 25 Kg/m2, n = 50). In this study, BMI (p < 0.001), waist circumference (WC) (p < 0.001), waist/hip ratio (p < 0.01), skinfolds (p < 0.001), sum of four skinfolds (p < 0.001), and percentage of body fat (%BF) (p < 0.001) were significantly higher in hyperlipidemic subjects as compared to normolipidemic controls. High %BF (> 25%) was observed in 26% of hyperlipidemic subjects and in 8% normolipidemic controls (p < 0.01). Using analysis of covariance (after adjusting for BMI), WC (p < 0.001), %BF (p < 0.01) and %BF/BMI ratio (p < 0.01) were significantly higher in the hyperlipidemic subjects. Intakes of total calories, total fat, saturated fat, carbohydrates, n-3 and n-6 fatty acids, dietary fiber, vitamin E and n-6/n-3 fatty acids ratio were statistically comparable between the two groups. In hyperlipidemic subjects biceps skinfold correlated negatively to levels of high-density lipoprotein cholesterol (r = -0.28, p < 0.05) and serum triglycerides correlated positively to intakes of carbohydrate (r = 0.31, p < 0.05), and dietary n-3 fatty acids (r = 0.34, p < 0.05).
  
  
  CONCLUSIONS
  Hyperlipidemic Asian Indian males, defined as "non-obese" based on BMI, had adverse profile of anthropometric parameters and excess %BF as compared to normolipidemic males. Therefore, while dealing with hyperlipidemic Asian Indians, physicians should consider anthropometric parameters (WC), %BF, and %BF/BMI ratio in addition to BMI in the clinical assessment.
authors.affiliation: Department of Medicine, All India Institute of Medical Sciences, New Delhi, India. anoopmisra@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Misra
authors.forename: D
authors.initials: D
authors.lastname: Athiko
authors.forename: R
authors.initials: R
authors.lastname: Sharma
authors.forename: R M
authors.initials: RM
authors.lastname: Pandey
authors.forename: N
authors.initials: N
authors.lastname: Khanna
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology*; D000328:Adult; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis; D001823:Body Composition / Q000502:physiology*; D001824:Body Constitution / Q000502:physiology*; D015992:Body Mass Index; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D004032:Diet; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000503:physiopathology*; D007194:India; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood; D012885:Skinfold Thickness; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D014280:Triglycerides; D002784:Cholesterol