title: Limited macular translocation: current concepts.
abstract: Macular translocation is a promising treatment modality that offers patients a chance to improve their vision, potentially to a level that may allow reading and driving. Proper patient selection avoids surgery in eyes with permanently damaged central retina and identifies eyes with the greatest potential for good visual outcomes. Functionally, those patients with recent-onset subfoveal CNV without permanent foveal neurosensory retina damage have the greatest likelihood of good visual outcome. Use of fixation evaluation by means of the SLO appears to greatly optimize patient selection. Anatomically, the best candidates have small minimum desired translocations and healthy RPE-Bruch membrane-choriocapillaris complex beyond the borders of the lesion. The exact role of limited macular translocation for the management of subfoveal CNV in this era of photodynamic therapy remains to be evaluated, and a pilot multicenter, randomized, clinical trial is under way to compare the efficacy of limited macular translocation with photodynamic therapy in eyes with subfoveal CNV secondary to AMD.
authors.affiliation: Retina Institute, Doheny Eye Institute, Keck School of Medicine, University of Southern California, DEI-3600, 1450 San Pablo Street, Los Angeles, CA 90033, USA.
authors.forename: Gildo Y
authors.initials: GY
authors.lastname: Fujii
authors.forename: Kah-Guan
authors.initials: KG
authors.lastname: Au Eong
authors.forename: Mark S
authors.initials: MS
authors.lastname: Humayun
authors.forename: Eugene
authors.initials: E
authors.lastname: de Juan
mesh_terms: D020256:Choroidal Neovascularization / Q000209:etiology / Q000601:surgery*; D002986:Clinical Trials as Topic; D005451:Fluorescein Angiography; D006801:Humans; D008266:Macula Lutea / Q000637:transplantation*; D008268:Macular Degeneration / Q000150:complications / Q000601:surgery*; D013508:Ophthalmologic Surgical Procedures