Bacterial colonization of nasal steroid inhalers in chronic rhinosinusitis.
BACKGROUND
The aim of this study was to determine if nasal steroid inhalers harbor bacteria.


METHODS
Nasal steroid inhalers were randomly selected from an adult patient population with chronic rhinosinusitis. Swab cultures of the tip of the nasal inhaler were obtained and submitted for microbiological analysis. Contemporaneous control cultures were obtained from freshly opened nasal steroid inhalers. Comparisons were conducted between bacterial recovery rates and types of organisms recovered from the patient and control groups.


RESULTS
Among 31 nasal inhalers in use, 14 inhalers (45%) were found to harbor bacteria. The most common organisms were coagulase negative Staphylococci (11 inhalers) followed by oral flora (2 inhalers) and bacillus species (1 inhaler). None of the 10 control cultures were found to harbor bacteria. Nasal steroid inhalers in use were more likely to have bacterial colonization than new inhalers (p = 0.008, chi-square).


CONCLUSIONS
Nasal steroid inhalers may harbor pathogenic bacteria. Therefore, they may serve as a vehicle for subsequent reinfection.
Bhattacharyya
Neil
N
Division of Otolaryngology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Kepnes
Lynn
L
D000328:Adult; D001900:Boston; D016009:Chi-Square Distribution; D004866:Equipment Contamination; D006801:Humans; D009330:Nebulizers and Vaporizers / Q000382:microbiology*; D012220:Rhinitis / Q000382:microbiology*; D012852:Sinusitis / Q000382:microbiology*; D013210:Staphylococcus / Q000302:isolation & purification