title: 1 Hz repetitive transcranial magnetic stimulation of the unaffected hemisphere ameliorates contralesional visuospatial neglect in humans.
abstract: The aim of the study was to investigate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected hemisphere can ameliorate visuospatial neglect. We treated three right brain damaged patients with left neglect. 900 pulses (1 Hz frequency) were given over left posterior parietal cortex every other day for 2 weeks. Patients performed a computerized task requiring length judgement of prebisected lines, tachistoscopically presented for 150 ms. With respect to rTMS the task was given 15 days before, at the beginning, at the end and 15 days after. At these times patients performed also line bisection and clock drawing tasks. rTMS induced a significant improvement of visuo-spatial performance that remained quite unchanged 15 days after. Patients performance at Time 3 and 4 improved also as concerns line bisection and clock drawing tasks.
authors.affiliation: Neurophysiological Unit, Institute of Neuropsychiatry, University of Palermo, Via G La Loggia, 1, 90129 Palermo, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Brighina
authors.forename: E
authors.initials: E
authors.lastname: Bisiach
authors.forename: M
authors.initials: M
authors.lastname: Oliveri
authors.forename: A
authors.initials: A
authors.lastname: Piazza
authors.forename: V
authors.initials: V
authors.lastname: La Bua
authors.forename: O
authors.initials: O
authors.lastname: Daniele
authors.forename: B
authors.initials: B
authors.lastname: Fierro
mesh_terms: D000368:Aged; D000377:Agnosia / Q000209:etiology / Q000534:rehabilitation*; D002545:Brain Ischemia / Q000150:complications; D004574:Electromagnetic Fields; D019054:Evoked Potentials, Motor / Q000528:radiation effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010296:Parietal Lobe / Q000503:physiopathology / Q000528:radiation effects*; D010468:Perceptual Disorders / Q000209:etiology / Q000534:rehabilitation; D011597:Psychomotor Performance / Q000528:radiation effects*; D013028:Space Perception; D016896:Treatment Outcome; D014796:Visual Perception