title: Infantile spasms as a cause of acquired perinatal visual loss.
abstract: BACKGROUND
  Visual abnormalities have been described in patients with infantile spasms (IS), an epileptic syndrome of early childhood.
  
  
  METHODS
  We report on 3 children who exhibited cortically mediated visual regression in association with the development of IS.
  
  
  RESULTS
  In 1 patient, loss of visual behavior was the presenting complaint. In all patients, visual behavior improved with treatment of seizures.
  
  
  CONCLUSIONS
  IS are a potentially treatable cause of cortically impaired vision in early childhood. Because visual behavior might improve when the seizures are treated, patients should be referred appropriately.
authors.affiliation: Department of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor, USA. brooksb@mail.nih.gov
authors.forename: Brian P
authors.initials: BP
authors.lastname: Brooks
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Simpson
authors.forename: Steven M
authors.initials: SM
authors.lastname: Leber
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Robertson
authors.forename: Steven M
authors.initials: SM
authors.lastname: Archer
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012640:Seizures / Q000150:complications / Q000188:drug therapy; D013036:Spasms, Infantile / Q000150:complications* / Q000188:drug therapy; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology* / Q000503:physiopathology; D014792:Visual Acuity
chemical_list: D000927:Anticonvulsants