Changes in patterns of antimicrobial susceptibility and integron carriage among Shigella sonnei isolates from southwestern Korea during epidemic periods.
Shigella sonnei isolates from southwestern Korea during the epidemic periods of 1998 to 2000 were genetically related. The antimicrobial susceptibilities of the outbreak-related isolates changed annually. All isolates carried class 2 integrons, and the outbreak-related isolates from 1999 also carried class 1 integrons. The antimicrobial susceptibilities of S. sonnei isolates are readily changed by antibiotic selective pressures, and integrons are responsible for resistance to antimicrobial agents commonly used to treat shigellosis.
Oh
Jae Young
JY
Department of Microbiology, College of Medicine, Seonam University, Namwon, ChunPook 590-711, Korea.
Yu
Hak Sun
HS
Kim
Sung Ki
SK
Seol
Seong Yong
SY
Cho
Dong Taek
DT
Lee
Je Chul
JC
D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004405:Dysentery, Bacillary / Q000453:epidemiology / Q000235:genetics / Q000382:microbiology*; D006801:Humans; D032023:Integrons / Q000502:physiology*; D007723:Korea / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D012764:Shigella sonnei / Q000187:drug effects* / Q000235:genetics