Staphylococcus lugdunensis carrying the mecA gene causes catheter-associated bloodstream infection in premature neonate.
A premature neonate had a catheter-associated bloodstream infection due to Staphylococcus lugdunensis. The MIC of oxacillin for the strain was >256 microg/ml, and the mecA gene of S. lugdunensis was detected by PCR. The infection was resolved after removal of the line and treatment with vancomycin for 2 weeks.
Tee
Wen Sim Nancy
WS
Clinical Microbiology Laboratory, KK Women's and Children's Hospital, Singapore, Republic of Singapore. nancyt@kkh.com.sg
Soh
Shui Yen
SY
Lin
Raymond
R
Loo
Liat Hui
LH
D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology*; D001426:Bacterial Proteins / Q000032:analysis / Q000235:genetics / Q000502:physiology*; D002404:Catheterization / Q000009:adverse effects; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013210:Staphylococcus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D014640:Vancomycin / Q000627:therapeutic use
D001426:Bacterial Proteins; C083616:mecA protein, Bacillus subtilis; D014640:Vancomycin