Abnormal pulp calcification in primary molars after fluoride supplementation.
Forty-five caries-free primary molars from children with continuous fluoride supplementation (n = 28) after birth and from children without fluoride prophylaxis (n = 17) were investigated by light microscopy. The following results were obtained: The prophylaxis group evidenced a special form of calcification consisting of fibrodentin-like hard tissue developing intramurally in the dentin wall especially at the pulp floor and spreading irregularily into the pulp cavity by displacing the degenerating pulp tissue (n = 24). These teeth were ankylosed in the bi- and trifurcation area as well as inside the roots. This kind of hard tissue was not observed in the teeth from untreated children. Only 5 children had greater calcifications attached at the pulp wall. Nevertheless, this difference was statistically significant (p = 0.001) and indicates a relationship between fluoride prophylaxis, the special form of pulp calcification and tooth ankylosis.
Holtgrave
Eva-Andrea
EA
Department of Orthodontics and Pediatric Dentistry, Klinikum Benjamin Franklin, Freie Universität, Berlin.
Hopfenmüller
Werner
W
Ammar
Sandra
S
D000293:Adolescent; D002327:Cariostatic Agents / Q000009:adverse effects*; D016022:Case-Control Studies; D002648:Child; D003784:Dental Pulp Calcification / Q000139:chemically induced* / Q000150:complications / Q000473:pathology; D019587:Dietary Supplements / Q000009:adverse effects*; D005260:Female; D005459:Fluorides / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008963:Molar / Q000187:drug effects; D020254:Tooth Ankylosis / Q000209:etiology; D014094:Tooth, Deciduous / Q000187:drug effects
D002327:Cariostatic Agents; D005459:Fluorides