title: Localization and diagnosis of septic endoprosthesis infection by using 99mTc-HMPAO labelled leucocytes.
abstract: The aim of this study was to evaluate, retrospectively, the diagnostic value of Tc hexamethylpropylene amine oxime (99mTc-HMPAO) labelled autologous leucocytes for the preferred septic localizations of the infection of the endoprosthesis. We retrospectively reviewed 67 patients with implanted endoprostheses. Diagnosis was found in 42/67 patients. In 25/67 patients we were able to negate an acute pathological process of infection of the endoprosthesis. Our patients were divided into three groups according to the type of endoprosthesis (hip joint, knee joint, shoulder joint). The localizations of the endoprosthesis disorders are shown. The preferred localizations of the acute infection of the hip endoprosthesis are the regio intertrochanterica and the middle part of the shaft of the prosthesis. The preferred localization of the acute infection of the knee endoprosthesis is the proximal shaft of the tibia. The preferred localization of the acute infection of the shoulder endoprosthesis is the distal end of the prosthesis in the proximal humerus. It is hoped that the knowledge of these preferred localizations of infection of endoprosthesis will help patients and doctors in diagnosis and treatment in the future.
authors.affiliation: Department of Radiology, Division of Nuclear Medicine, Karl-Franzens University Graz, Austria. ge.wolf@kfunigraz.ac.at
authors.forename: G
authors.initials: G
authors.lastname: Wolf
authors.forename: R M
authors.initials: RM
authors.lastname: Aigner
authors.forename: T
authors.initials: T
authors.lastname: Schwarz
authors.forename: M P
authors.initials: MP
authors.lastname: Lorbach
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D007595:Joint Prosthesis / Q000009:adverse effects* / Q000145:classification; D007720:Knee Prosthesis / Q000009:adverse effects; D007962:Leukocytes / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology; D016459:Prosthesis-Related Infections / Q000145:classification / Q000000981:diagnostic imaging* / Q000209:etiology; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000097:blood; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012785:Shoulder Joint / Q000000981:diagnostic imaging / Q000601:surgery; D019690:Technetium Tc 99m Exametazime / Q000097:blood
chemical_list: D019275:Radiopharmaceuticals; D019690:Technetium Tc 99m Exametazime