title: Vital bleaching with two at-home professional systems.
abstract: OBJECTIVE
  To compare the whitening effectiveness of two professional vital bleaching systems in a randomized clinical trial.
  
  
  METHODS
  Balancing for baseline color, 6 9 adult volunteers were randomized to either a whitening strip containing 6.5% hydrogen peroxide (Professional Crest Whitestrips) or a custom tray-based system using both hydrogen and carbamide peroxide (Nite White Excel2). Total contact time was 21 hours for the strip system and 28 hours for the 10% carbamide peroxide equivalent tray system. Whitening response was measured objectively as L*a*b* from digital images of the maxillary anterior teeth.
  
  
  RESULTS
  Both treatments resulted in significant (P < 0.01) improvements in yellowness (deltab*), brightness (deltaL*) and overall color (deltaE*). For between group comparisons, strip subjects had a statistically significant or directionally favorable whitening response relative to the tray system at intermediary time points, while at the end-of-treatment, the strip group had highly statistically significant (P < or = 0.005), superior whitening response for all color parameters measured in the study. Both treatments were generally well tolerated, with 35-40% of the subjects in each group reporting minor tooth sensitivity or gingival irritation.
authors.affiliation: University of Florida, Gainesville, USA.
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Karpinia
authors.forename: Ingvar
authors.initials: I
authors.lastname: Magnusson
authors.forename: Paul A
authors.initials: PA
authors.lastname: Sagel
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Zhou
authors.forename: Robert W
authors.initials: RW
authors.lastname: Gerlach
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000077463:Carbamide Peroxide; D003116:Color; D003807:Dentin Sensitivity / Q000139:chemically induced; D004338:Drug Combinations; D004867:Equipment Design; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000009:adverse effects / Q000627:therapeutic use; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D016877:Oxidants / Q000009:adverse effects / Q000627:therapeutic use; D010545:Peroxides / Q000009:adverse effects / Q000627:therapeutic use; D023861:Photography, Dental; D013280:Stomatitis / Q000139:chemically induced; D013997:Time Factors; D014070:Tooth / Q000473:pathology; D014073:Tooth Bleaching / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D014075:Tooth Discoloration / Q000628:therapy; D016896:Treatment Outcome; D014508:Urea / Q000009:adverse effects / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D004338:Drug Combinations; D016877:Oxidants; D010545:Peroxides; D000077463:Carbamide Peroxide; D014508:Urea; D006861:Hydrogen Peroxide