Bile duct cancer 25 years after choledochoduodenostomy: a case report.
We describe a 65-year-old man who had undergone choledochoduodenostomy (CDS) for choledocholithiasis 25 years prior to admission to our hospital for cholangitis. Abdominal sonography and computerized tomography (CT) scan revealed a tumor mass at the hilar region with bilateral intrahepatic duct dilatation. Upper gastrointestinal endoscopic examination indicated the site of the CDS. Biopsy was taken from the mucosa of the bile duct, and pathology revealed well-differentiated adenocarcinoma. CT scan and angiography further confirmed unresectable hilar bile duct cancer. Conservative treatment with intra-arterial chemotherapy was arranged. After briefly reviewing the hypothesized pathogenesis and radiographic diagnosis of this rare case, we recommend that chronic cholangitis consequent to CDS should be closely followed for late development of biliary tract malignancy.
Kuo
Kung-Kai
KK
Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. kkkuo@cc.kmu.edu.tw
Sheen
Pai-Ching
PC
Lee
King-Teh
KT
Sheen
Maw-Chang
MC
Chuang
Shih-Chang
SC
Wang
Sen-Ren
SR
Wang
Wen-Ming
WM
D000368:Aged; D001650:Bile Duct Neoplasms / Q000209:etiology*; D002761:Cholangitis / Q000150:complications; D002768:Choledochostomy / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013997:Time Factors