title: Levels and congener pattern of polychlorinated biphenyls in the blubber of the Mediterranean bottlenose dolphins Tursiops truncatus.
abstract: Isomer specific concentrations of individual polychlorinated biphenyls (PCBs) including toxic non-ortho (IUPAC 77, 126, 169) and mono-ortho (105, 118, 156) coplanar congeners were determined in the blubber of nine bottlenose dolphins (Tursiops truncatus) stranded along the Eastern Italian coast. The total PCB concentrations ranged from 3534 to 24375 ng/g wet wt. The PCB profile was dominated by congeners 138 and 153 collectively accounting for 55% of the total PCB concentrations. Among the most toxic congeners the order of abundance was 126>169>77. The mean total 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) equivalent of six coplanar PCBs in the blubber of bottlenose dolphins was 45596 pg/g. Non-ortho congeners contributed greater to the 2,3,7,8-TCDD toxic equivalents than mono-ortho members. Particularly, PCB 126 was the major contributor to the estimated toxic potency of PCBs in dolphins.
authors.affiliation: Pharmacological-Biologic Department, Chemistry and Biochemistry Section, Medicine Veterinary Faculty, University of Bari, Strada Prov. le per Casamassima km 3, 70010 Valenzano, Bari, Italy.
authors.forename: M M
authors.initials: MM
authors.lastname: Storelli
authors.forename: G O
authors.initials: GO
authors.lastname: Marcotrigiano
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry*; D000818:Animals; D004289:Dolphins; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000032:analysis / Q000493:pharmacokinetics*; D005260:Female; D007558:Italy; D008297:Male; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000493:pharmacokinetics*
chemical_list: D004785:Environmental Pollutants; D011078:Polychlorinated Biphenyls