title: Termination of translation: interplay of mRNA, rRNAs and release factors?
abstract: Termination of translation in eukaryotes has focused recently on functional anatomy of polypeptide chain release factor, eRF1, by using a variety of different approaches. The tight correlation between the domain structure and different functions of eRF1 has been revealed. Independently, the role of prokaryotic RF1/2 in GTPase activity of RF3 has been deciphered, as well as RF3 function itself.
authors.affiliation: Engelhardt Institute of Molecular Biology, 119991 Moscow, Russia. kissel@imb.ac.ru
authors.forename: Lev
authors.initials: L
authors.lastname: Kisselev
authors.forename: Måns
authors.initials: M
authors.lastname: Ehrenberg
authors.forename: Ludmila
authors.initials: L
authors.lastname: Frolova
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D018388:Codon, Terminator; D020558:GTP Phosphohydrolases / Q000378:metabolism; D006801:Humans; D008957:Models, Genetic; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010454:Peptide Termination Factors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D014176:Protein Biosynthesis; D011487:Protein Conformation; D012333:RNA, Messenger / Q000378:metabolism*; D012335:RNA, Ribosomal / Q000378:metabolism*
chemical_list: D018388:Codon, Terminator; C489002:ETF1 protein, human; D010454:Peptide Termination Factors; D012333:RNA, Messenger; D012335:RNA, Ribosomal; D020558:GTP Phosphohydrolases