Impact of asymptomatic maternal malaria parasitaemia at parturition on perinatal outcome.
A cross-sectional study involving 564 parturients who delivered singleton babies and 214 matched non-pregnant controls was carried out to determine the prevalence and impact of asymptomatic maternal malaria parasitaemia at parturition on the perinatal outcome. One hundred and forty (24.8%) parturients and 50 (23.4%) non-pregnant women were found to have asymptomatic malaria parasitaemia, respectively, while the congenital malaria rate in the neonates of the parasitaemic parturients was 0.7%. The incidence of malaria parasitaemia was higher in the para 2 and over (29.33%) as compare to the para 1 (21.43%) and primigravid (18.42%). There was no significant difference between the mean birth weight of infants delivered by parasitaemic parturients (2.93+/-0.61 kg) and aparasitaemic parturients (3.07+/-0.32 kg) (P=0.501). There was also no significant difference when comparing the mean placental weight of the parasitaemic mothers (0.60+/-0.15 kg) with that of the aparasitaemic mothers (0.62+/-0.20 kg) (P=0.329). Only in the para 2 and over was the mean placental weight of the parasitaemic mothers significantly lower than that of the aparasitaemia mothers (0.46+/-0.16 kg; 0.66+/-0.23 kg P=0.035). The mean packed cell volume of the parasitaemics parturients (30.89+/-1.87) was significantly lower than the aparasitaemic parturients (31.98+/-2.25) (P<0.001). Significant difference was not achieved between the parasitaemics and aparasitaemics inrespect of apgar score at 1 minute, or at 5 minutes, premature births (16.43%; 15.33%; P>0.05), stillbirth rate (3.57%; 2.59, P>0.05), mean placental index (0.204, 0.202, P>0.50) and mode of delivery. The findings in this study show that even though malaria parasitaemia is prevalent in our locality, the effects on maternal and fetal wellbeing are comparable with the aparasitaemics.
Sule-Odu
A O
AO
Department of Obstetrics and Gynaecology, Obafemi Awolowo College of Health Sciences, Ogun State University Teaching Hospital, PMB 2001, Sagamu, Ogun State, Nigeria.
Ogunledun
A
A
Olatunji
A O
AO
D001034:Apgar Score; D001724:Birth Weight; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D016778:Malaria, Falciparum / Q000150:complications* / Q000473:pathology; D009549:Nigeria; D018512:Parasitemia / Q000150:complications*; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000473:pathology; D011256:Pregnancy Outcome