[A case of idiopathic hypereosinophilic syndrome with hepatic involvement in a 5-year-old boy].
Idiopathic hypereosinophilic syndrome is defined as the presence of prolonged eosinophilia without an identifiable underlying cause and with evidence of end-organ dysfunction. The organs involved are the heart, bone marrow, nervous system, lungs, liver, skin, and gastrointestinal tract. Hepatic involvement is found in about 30% of patients of idiopathic hypereosinophilic syndrome. It occurs rarely in infants and children. In this report, we experienced one case of idiopathic hypereosinophilic syndrome with hepatic involvement in a 5-year-old boy who complained of intermittent fever and right upper quadrant abdominal pain. An abdominal ultrasound examination revealed an ill-defined low-echoic lesion in the liver. Pathologic findings of a biopsy specimen clearly showed the infiltration of eosinophils in the liver. Laboratory data disclosed absolute eosinophilia. There was no evidence of allergic disease or parasitic infestation.
Kim
Young Mi
YM
Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea.
Lee
Yoon Jin
YJ
Park
Jae Hong
JH
Lee
Jun Woo
JW
Lee
Chang Hun
CH
D002675:Child, Preschool; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000175:diagnosis; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male