title: [Cutaneous vasculitis, myelodysplasia and relapsing polychondritis].
abstract: BACKGROUND
  Relapsing polychondritis is a rare autoimmune disease, characterized by recurrent inflammation of cartilaginous tissues. In some cases, many other tissues can be involved.
  
  
  METHODS
  We describe the case of a 64 year-old man with relapsing polychondritis, whose first symptoms were papulonodular and mucosal aphthous lesions. The skin biopsy revealed vasculitis without leukocytoclasic features. The diagnostic of relapsing polychondritis was made only two years later, thanks to recurrent auricular chondritis. Since the beginning, the disease was associated with a myelodysplasia.
  
  
  CONCLUSIONS
  Dermatological manifestations are noticed in less than 50 p. 100 of cases during the evolution of relapsing polychondritis. An association with a myelodysplasia has already been reported, and it could be a particular form of relapsing polychondritis. Myelodysplasic syndromes are more frequently associated with relapsing polychondritis than with other vasculitis. It must be sought especially when cutaneous and mucosal manifestations exist.
authors.affiliation: Service de Dermatologie, CHU Trousseau, route de Loches, 37044 Tours Cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Németh-Normand
authors.forename: L
authors.initials: L
authors.lastname: Machet
authors.forename: L
authors.initials: L
authors.lastname: Vaillant
authors.forename: V
authors.initials: V
authors.lastname: Fontes
authors.forename: T
authors.initials: T
authors.lastname: Lefrancq
authors.forename: G
authors.initials: G
authors.lastname: Lorette
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009436:Neural Tube Defects / Q000150:complications* / Q000473:pathology; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000473:pathology; D012008:Recurrence; D012871:Skin Diseases / Q000209:etiology; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology