The natural history of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is a multistage disease whose occurrence is linked to environmental, dietary and life-style factors. Risk factors for HCC have been grouped into two clusters, physiologic and pathologic factors. Much evidence indicates that these risk factors may interact with each other either as a group or as a single factor to modulate development of liver cancer.
Romeo
Raffaella
R
Department of Internal Medicine, University of Milan, IRCCS Maggiore Hospital, Via Pace, 9, 20122 Milan, Italy. raffaella.romeo@unimi.it
Colombo
Massimo
M
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000209:etiology / Q000473:pathology* / Q000821:virology; D004032:Diet; D006509:Hepatitis B / Q000150:complications; D006526:Hepatitis C / Q000150:complications; D006728:Hormones / Q000502:physiology; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology / Q000473:pathology* / Q000821:virology; D009367:Neoplasm Staging; D012306:Risk
D006728:Hormones