title: Pd-catalyzed allylic substitution using nucleophilic N-heterocyclic carbene as a ligand.
abstract: A nucleophilic N-heterocyclic carbene has been successfully used in a Pd(0)-catalyzed allylic substitution for the first time. It was found that allylic substitution with a soft nucleophile using a Pd-carbene catalyst proceeds via retention of configuration, the stereochemical reaction pathway being the same as that of the reaction using a Pd-phosphine complex. [reaction--see text]
authors.affiliation: Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sato
authors.forename: Taro
authors.initials: T
authors.lastname: Yoshino
authors.forename: Miwako
authors.initials: M
authors.lastname: Mori