Generation of retroviral packaging and producer cell lines for large-scale vector production with improved safety and titer.
Dubensky
Thomas W
TW
Cerus Corporation, Concord, CA, USA.
Sauter
Sybille L
SL
D000818:Animals; D002460:Cell Line; D015686:Gene Products, env / Q000235:genetics / Q000378:metabolism; D015683:Gene Products, gag / Q000235:genetics / Q000378:metabolism; D015684:Gene Products, pol / Q000235:genetics / Q000378:metabolism; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods; D005822:Genetic Vectors; D006801:Humans; D008562:Membrane Glycoproteins / Q000235:genetics / Q000378:metabolism; D051379:Mice; D008979:Moloney murine leukemia virus / Q000235:genetics*; D012190:Retroviridae / Q000235:genetics* / Q000502:physiology; D014759:Viral Envelope Proteins / Q000235:genetics / Q000378:metabolism; D019065:Virus Assembly; D014776:Virus Cultivation; D014779:Virus Replication
C028391:G protein, vesicular stomatitis virus; D015686:Gene Products, env; D015683:Gene Products, gag; D015684:Gene Products, pol; D008562:Membrane Glycoproteins; D014759:Viral Envelope Proteins