Lethal factor to mice produced by Escherichia coli isolated from chickens with swollen head syndrome.
A lethal toxin similar to Bacillus cererus lethal toxin was detected in the culture supernatants of Escherichia coli isolated from chickens with swollen head syndrome. The lethal activity was heat-labile, protease-sensitive and killed mice within 10 min. The light microscopy of the histopathological studies revealed that the principal organ affected by this toxin was the lung but the liver and kidneys also showed lesions. The relevance of this lethal activity from E. coli remains to be determined.
Salvadori
Marcia Regina
MR
Departamento de Microbiologia e Imunologia, Instituto to de Biologia, Universidade Estadual de Campinas, Campinas, SP Brazil, cep 13081-970.
Chudzinski-Tavassi
Ana Marisa
AM
Baccaro
Maria Regina
MR
Ferreira
Claudete Serrano Astolfi
CS
Ferreira
Antonio José Piantino
AJ
Prado-Franceschi
Júlia
J
Yano
Tomomasa
T
D000818:Animals; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000633:toxicity*; D002645:Chickens; D004768:Enterotoxins / Q000096:biosynthesis / Q000633:toxicity*; D004926:Escherichia coli / Q000302:isolation & purification / Q000378:metabolism*; D004927:Escherichia coli Infections / Q000382:microbiology / Q000401:mortality* / Q000473:pathology / Q000662:veterinary; D005260:Female; D008168:Lung / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D011201:Poultry Diseases / Q000382:microbiology*
D001426:Bacterial Proteins; D004768:Enterotoxins; C040792:enterotoxin, Bacillus cereus