title: Intratumoral bleeding in meningioma after gamma knife radiosurgery.
abstract: OBJECTIVE
  The authors evaluated whether gamma knife radiosurgery (GKS) could be a causative factor in intratumoral bleeding in meningiomas.
  
  
  METHODS
  Gamma knife radiosurgery was used in the treatment of 173 meningiomas during a 10-year period. Four patients suffered post-GKS intratumoral hemorrhage. The course in these patients was reviewed. Four of 173 patients suffered an intratumoral hemorrhage during a follow-up period of 1 to 8 years. The risk of intratumoral bleeding after GKS for meningioma was 2.3%. Intracystic hemorrhage occurred in two patients 1 and 5 years, respectively, after radiosurgery. In the other two cases intratumoral bleeding occurred 2 and 8 years, respectively, after radiosurgery. Histological examination in three cases found no specific findings related to the postradiosurgical changes.
  
  
  CONCLUSIONS
  Because the reported risk of spontaneous intratumoral bleeding in meningiomas is 1.3 to 2.7%, the incidence in this series was not unduly high. Radiosurgery itself could not be shown to be a significant factor in the development of the intratumoral bleeding.
authors.affiliation: Department of Neurological Surgery, Asan Medical Center, Seoul, Korea. ykwon@www.amc.seoul.kr
authors.forename: Yang
authors.initials: Y
authors.lastname: Kwon
authors.forename: Jae Sung
authors.initials: JS
authors.lastname: Ahn
authors.forename: Sang Ryong
authors.initials: SR
authors.lastname: Jeon
authors.forename: Jeong Hoon
authors.initials: JH
authors.lastname: Kim
authors.forename: Chang Jin
authors.initials: CJ
authors.lastname: Kim
authors.forename: Jung Kyo
authors.initials: JK
authors.lastname: Lee
authors.forename: Byung Duk
authors.initials: BD
authors.lastname: Kwun
authors.forename: Do Hee
authors.initials: DH
authors.lastname: Lee
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Kim
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000209:etiology* / Q000473:pathology; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery*; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications; D016634:Radiosurgery / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed