[Glutamine metabolism in the liver after partial hepatectomy in chronic hepatitis].
A long-term treatment of female rats with CCl4 caused a decrease of glutamine content in the liver. This decrease may be attributed to stable reduction of glutamine synthetase activity and slightly elevated (or unchanged) phosphate-dependent glutaminase. Partial hepatectony (15-20% of the liver) did not normalise glutamine metabolism.
Savilov
P N
PN
Burdenko Voronezh State Medical Academy, 394622 Voronezh, Stydencheskaya st., 10.
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism / Q000601:surgery; D005260:Female; D005974:Glutamate-Ammonia Ligase / Q000037:antagonists & inhibitors; D005972:Glutaminase / Q000378:metabolism; D005973:Glutamine / Q000378:metabolism*; D006498:Hepatectomy; D006521:Hepatitis, Chronic / Q000378:metabolism* / Q000601:surgery; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D011184:Postoperative Period; D051381:Rats
D005973:Glutamine; D005972:Glutaminase; D005974:Glutamate-Ammonia Ligase