title: [A case of idiopathic hypereosinophilic syndrome with hepatic involvement in a 5-year-old boy].
abstract: Idiopathic hypereosinophilic syndrome is defined as the presence of prolonged eosinophilia without an identifiable underlying cause and with evidence of end-organ dysfunction. The organs involved are the heart, bone marrow, nervous system, lungs, liver, skin, and gastrointestinal tract. Hepatic involvement is found in about 30% of patients of idiopathic hypereosinophilic syndrome. It occurs rarely in infants and children. In this report, we experienced one case of idiopathic hypereosinophilic syndrome with hepatic involvement in a 5-year-old boy who complained of intermittent fever and right upper quadrant abdominal pain. An abdominal ultrasound examination revealed an ill-defined low-echoic lesion in the liver. Pathologic findings of a biopsy specimen clearly showed the infiltration of eosinophils in the liver. Laboratory data disclosed absolute eosinophilia. There was no evidence of allergic disease or parasitic infestation.
authors.affiliation: Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea.
authors.forename: Young Mi
authors.initials: YM
authors.lastname: Kim
authors.forename: Yoon Jin
authors.initials: YJ
authors.lastname: Lee
authors.forename: Jae Hong
authors.initials: JH
authors.lastname: Park
authors.forename: Jun Woo
authors.initials: JW
authors.lastname: Lee
authors.forename: Chang Hun
authors.initials: CH
authors.lastname: Lee
mesh_terms: D002675:Child, Preschool; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000150:complications* / Q000175:diagnosis; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male