title: [Sentinel lymph node after intramammary injection of superparamagnetic iron oxide].
abstract: The purpose of this study was to evaluate enhancement (signal loss) of the axillary lymph nodes on MR lymphography after intramammary injection of superparamagnetic iron oxide (Ferumoxides) for detection of the sentinel lymph node. MR lymphography was performed in a total of 11 patients with breast cancer without palpable axillary lymph node swelling before operation. Coronal and axial images were obtained before and after intramammary injection of 1.5 ml Ferumoxides adjacent to the breast tumor. In all patients, decreased intensity was recognized in the axillary lymph nodes. MR lymphography could detect the sentinel lymph node with its decreased signal intensity 20 minutes after the intramammary injection of Ferumoxides.
authors.affiliation: Department of Radiology, Akita University School of Medicine.
authors.forename: Koichi
authors.initials: K
authors.lastname: Ishiyama
authors.forename: Ryuji
authors.initials: R
authors.lastname: Sashi
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Katayose
authors.forename: Noriaki
authors.initials: N
authors.lastname: Tomura
authors.forename: Jiro
authors.initials: J
authors.lastname: Watarai
authors.forename: Komei
authors.initials: K
authors.lastname: Narita
mesh_terms: D001365:Axilla; D001940:Breast; D001943:Breast Neoplasms / Q000473:pathology*; D003287:Contrast Media / Q000008:administration & dosage; D003911:Dextrans; D005260:Female; D052203:Ferrosoferric Oxide; D006801:Humans; D007267:Injections; D007501:Iron / Q000008:administration & dosage; D008198:Lymph Nodes / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles; D008875:Middle Aged; D010087:Oxides / Q000008:administration & dosage; D019047:Phantoms, Imaging
chemical_list: D003287:Contrast Media; D003911:Dextrans; D058185:Magnetite Nanoparticles; D010087:Oxides; D007501:Iron; C065507:ferumoxides; D052203:Ferrosoferric Oxide