[Biochemical characterization of viral hepatitis in humans, using and not using narcotics].
OBJECTIVE
To compare biochemical changes in viral hepatitis (VH) in drug abusers (DA) and non-abusers (NA).


METHODS
Hepatic function was examined in 1125 patients with parenteral hepatitis, 540 of them were DA. Transaminases tests and protein precipitation tests were made at the disease height and in convalescence.


RESULTS
In DA patients with VH biochemical changes were found more frequently than in NA. In convalescence, elevation of alaninaminotransferase was higher in DA than in NA.


CONCLUSIONS
Drug abuse in VH patients influences biochemical indices. In DA with VH correlations of biochemical indices with the disease severity are less frequent than in NA, while changes of biochemical indices reflecting hepatic function occur more frequently and persist longer.
Tomilka
G S
GS
Zhuravlev
Ia A
IaA
Gordinskaia
N M
NM
D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D006525:Hepatitis, Viral, Human / Q000097:blood* / Q000150:complications / Q000201:enzymology / Q000503:physiopathology; D006801:Humans; D008111:Liver Function Tests; D019966:Substance-Related Disorders / Q000150:complications*
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase