Protein A immunoadsorption in a pregnant woman with habitual abortion.
The role of antibodies in the occurrence of recurrent spontaneous miscarriage is well known. However there are many controversial issues in the management of habitual abortion. This paper describes the effect of Protein A immunoadsorption on serum levels of these antibodies and its impact on a case of a successfully treated woman in a outpatient department without need for a central venous catheter. Given the favourable clinical results described in our paper we think it may be relevant for some worse cases in clinical practice and will interest your readers.
Hickstein
H
H
Medizinische Fakultät, Klinik für Innere Medizin, Abteilung Nephrologie, Universität Rostock, E. Heydemann Str. 6, D-18055 Rostock, Germany. heiko.hickstein@med.uni-rostock.de
Barz
D
D
Külz
T
T
Korten
G
G
Müller
H
H
Schmidt
R
R
D000026:Abortion, Habitual; D000022:Abortion, Spontaneous / Q000517:prevention & control*; D020016:Activated Protein C Resistance / Q000628:therapy; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D016824:Antigens, Human Platelet / Q000276:immunology; D001241:Aspirin / Q000627:therapeutic use; D002585:Cesarean Section; D003131:Combined Modality Therapy; D005165:Factor V / Q000032:analysis; D005260:Female; D006680:HLA Antigens / Q000276:immunology; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology; D007163:Immunosorbent Techniques; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007231:Infant, Newborn; D007518:Isoantibodies / Q000097:blood* / Q000276:immunology; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000276:immunology; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy; D013205:Staphylococcal Protein A; D013921:Thrombocytopenia / Q000151:congenital / Q000209:etiology
D000925:Anticoagulants; D016824:Antigens, Human Platelet; D006680:HLA Antigens; D006495:Heparin, Low-Molecular-Weight; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D007518:Isoantibodies; D019038:Platelet Glycoprotein GPIb-IX Complex; D013205:Staphylococcal Protein A; C095381:factor V Leiden; D005165:Factor V; D001241:Aspirin; D008775:Methylprednisolone