title: Phosphodiesterase 3 (PDE3) attenuates insulin secretion from the human pancreas: a specific PDE3 inhibitor improves insulin secretion in type II diabetes mellitus.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Okada
authors.forename: Kihachi
authors.initials: K
authors.lastname: Ohshima
authors.forename: Masatomo
authors.initials: M
authors.lastname: Mori
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors* / Q000502:physiology; D054684:Cyclic Nucleotide Phosphodiesterases, Type 3; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000503:physiopathology; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D010179:Pancreas / Q000378:metabolism*
chemical_list: D004791:Enzyme Inhibitors; D007328:Insulin; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D054684:Cyclic Nucleotide Phosphodiesterases, Type 3