title: Atypical lipomatous tumour (lipoma-like well-differentiated liposarcoma) arising in a pulmonary hamartoma and clinically presenting with pneumothorax.
abstract: We document an uncommon variant of pulmonary hamartoma (PH), discovered in the left upper lobe of a 60-year-old man after an episode of pneumothorax, a unique clinical presentation for such an occurrence. The tumour showed a prominent leaf-like pattern and was mainly composed of mature fat with adipocytes of different size and scattered throughout lipoblasts and floret-like cells. A lobectomy was performed and more than 7 years after surgery the patient's course is still uneventful. This case represents an exceedingly rare example of an histologically malignant change in PH and bears a close clinicopathologic resemblance to atypical lipomatous tumours of soft tissues.
authors.affiliation: Department of Pathological Anatomy and Forensic Medicine, Section of Pathology, University of Modena and Reggio Emilia, Via del Pozzo, 71-41100, Modena, Italy. rossi.giulio@unimo.it
authors.forename: Giulio
authors.initials: G
authors.lastname: Rossi
authors.forename: Alberto
authors.initials: A
authors.lastname: Cavazza
authors.forename: Riccardo
authors.initials: R
authors.lastname: Valli
authors.forename: Pietro
authors.initials: P
authors.lastname: Torricelli
authors.forename: Luca
authors.initials: L
authors.lastname: Richeldi
authors.forename: Francesco
authors.initials: F
authors.lastname: Rivasi
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Brambilla
mesh_terms: D006222:Hamartoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008080:Liposarcoma / Q000150:complications* / Q000473:pathology*; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011030:Pneumothorax / Q000150:complications* / Q000473:pathology; D016896:Treatment Outcome