[The effect of the duration of adaptation to laboratory conditions on the passive avoidance reflex in rats].
Influence of adaptation degree in new conditions on the passive avoidance was studied. The short period of habituation (3 days) positively influenced the rats' ability for memory trace retrieval. A negative correlation between the step through latency and anxiety in the elevated plus-maze, was shown. Prolongation of adaptation up to 9 days reduced levels of anxiety and retrieval of conditioned response. Modulating role of adaptation degree causing various anxiety levels in passive avoidance, is discussed.
Loskutova
L V
LV
Institute of Physiology, Russian Acad. Med. Sci., 4 Timakov St., Novosibirsk 630117, Russia.
Dubrovina
N I
NI
D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D001007:Anxiety / Q000503:physiopathology / Q000523:psychology; D001362:Avoidance Learning / Q000502:physiology*; D006185:Habituation, Psychophysiologic / Q000502:physiology*; D008297:Male; D018782:Maze Learning / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors