title: [Hemolytic activity and toxigenicity of Vibrio cholerae of different serogroups].
abstract: Experimental data on the comparative evaluation of the hemolytic activity of ctx+ Hly- and ctx- Hly+ V. cholerae, serogroups O1 and O139, in the process of their cultivation in different nutrient media are presented. The capacity of ctx+ V. cholerae of both serogroups cultivated under the conditions of iron deficiency, for the production of hemolysin capable of lyzing sheep red blood cells was shown. Hemolysin produced by ctx- strains of V. cholerae was synthesized under any conditions. The study of hemolysin preparations obtained from ctx- and ctx+ strains of V. cholerae, serogroups O1 and O139, revealed that they were biologically and immunologically similar.
authors.affiliation: Research Institute for Plague Control, Rostov-on-Don, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Men'shikova
authors.forename: L S
authors.initials: LS
authors.lastname: Podosinnikova
authors.forename: A V
authors.initials: AV
authors.lastname: Mironova
authors.forename: O I
authors.initials: OI
authors.lastname: Sal'nikova
mesh_terms: D000818:Animals; D000833:Animals, Suckling; D002772:Cholera Toxin / Q000276:immunology / Q000378:metabolism*; D006224:Cricetinae; D003470:Culture Media; D004912:Erythrocytes / Q000276:immunology; D006460:Hemolysin Proteins / Q000276:immunology / Q000378:metabolism*; D006801:Humans; D007501:Iron; D011817:Rabbits; D012756:Sheep; D014734:Vibrio cholerae / Q000378:metabolism* / Q000472:pathogenicity
chemical_list: D003470:Culture Media; D006460:Hemolysin Proteins; D002772:Cholera Toxin; D007501:Iron