[Determination of cinnamic acid in Cinnamomum cassia presl after compatibility in Coptis chinensis Franch].
OBJECTIVE
Studying changes of chemical constituents of Cinnamomum cassia after compatibility in Coptis chinensis; determining the amount of cinnamic acid in the decoction.


METHODS
An YWG C18 column was used with a mobile phase of CH3CN-0.01% H3PO4(27:73), the flow rate was 1.0 ml.min-1 and the detection wavelength was 280 nm.


CONCLUSIONS
The calibration curve of cinnamic acid had good linear relationship in the range of 0.112-4.48 micrograms. The average recovery was 100.0%, the relative standard deviation was 0.66%. The amount of cinnamic acid was decreased in the decoction, and the decreased degree was related with the ratio of C. chinensis to C. cassia.
Xu
Y C
YC
College of Chinese Pharmacy, Beijing University of Traditional Chinese Medicine, Beijing 100029, China.
Wei
L X
LX
Wang
Y L
YL
D002851:Chromatography, High Pressure Liquid; D002934:Cinnamates / Q000032:analysis*; D032904:Cinnamomum aromaticum / Q000737:chemistry*; D039323:Coptis / Q000737:chemistry*; D004338:Drug Combinations; D010946:Plants, Medicinal / Q000737:chemistry*
D002934:Cinnamates; D004338:Drug Combinations; C029010:cinnamic acid