MMDB: Entrez's 3D-structure database.
Three-dimensional structures are now known within most protein families and it is likely, when searching a sequence database, that one will identify a homolog of known structure. The goal of Entrez's 3D-structure database is to make structure information and the functional annotation it can provide easily accessible to molecular biologists. To this end, Entrez's search engine provides several powerful features: (i) links between databases, for example between a protein's sequence and structure; (ii) pre-computed sequence and structure neighbors; and (iii) structure and sequence/structure alignment visualization. Here, we focus on a new feature of Entrez's Molecular Modeling Database (MMDB): Graphical summaries of the biological annotation available for each 3D structure, based on the results of automated comparative analysis. MMDB is available at: http://www.ncbi.nlm.nih.gov/Entrez/structure.html.
Chen
Jie
J
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Anderson
John B
JB
DeWeese-Scott
Carol
C
Fedorova
Natalie D
ND
Geer
Lewis Y
LY
He
Siqian
S
Hurwitz
David I
DI
Jackson
John D
JD
Jacobs
Aviva R
AR
Lanczycki
Christopher J
CJ
Liebert
Cynthia A
CA
Liu
Chunlei
C
Madej
Thomas
T
Marchler-Bauer
Aron
A
Marchler
Gabriele H
GH
Mazumder
Raja
R
Nikolskaya
Anastasia N
AN
Rao
Bachoti S
BS
Panchenko
Anna R
AR
Shoemaker
Benjamin A
BA
Simonyan
Vahan
V
Song
James S
JS
Thiessen
Paul A
PA
Vasudevan
Sona
S
Wang
Yanli
Y
Yamashita
Roxanne A
RA
Yin
Jodie J
JJ
Bryant
Stephen H
SH
D000818:Animals; D003196:Computer Graphics; D030562:Databases, Protein; D021621:Imaging, Three-Dimensional; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry; D040681:Structural Homology, Protein
D011506:Proteins