[Distribution of bacteria and analysis of their sensibility to antibiotics in patients with hospital-acquired pneumonia].
OBJECTIVE
This study was explore the distribution of the bacteria and their sensibility to antibiotics in hospital-acquired pneumonia.


METHODS
One hundred and ninety-six bacterium species were collected in patients with the hospital-acquired pneumonia to make sputum culture. The sensibility of the bacteria to antibiotics were examined by KB paper method and the minimal-inhibitory-concentration by gel double multiple dilute method.


RESULTS
Most of the G- bacteria were pseudomonas aeruginosa (30%) and klebsiella bacillus (22%). Most of the G+ bacteria were staphylococcus epidermidis (14%) and staphylococcus aureus (12%). G- bacteria were sensitive to impienem(98%), cefoperazone(90%), ceftriaxone(90%), leftazidime(92%), ciprofloxacin(90%), and amikacin(89%). The sensibility of vancomycin to G+ bacteria was 100%.


CONCLUSIONS
The pseudomonas aeruginosa, klebsiella bacillus, staphylococcus epidermidis, and staphylococcus aureus are the most important bacteria in patients with hospital-acquired pneumonia. Imipenem, cefoperazone, ceftriazone, leftazidime, ciprofloxacin, amikacin, and vancomycin are effective antibiotics for treating hospital-acquired pneumonia.
Cheng
W C
WC
Department of Respiratory Internal Medicine, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Xiang
X D
XD
Chen
P
P
Zan
J N
JN
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002438:Cefoperazone / Q000494:pharmacology; D002443:Ceftriaxone / Q000494:pharmacology; D003428:Cross Infection / Q000382:microbiology*; D005260:Female; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D007710:Klebsiella Infections / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000382:microbiology*; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013203:Staphylococcal Infections / Q000382:microbiology*; D013212:Staphylococcus epidermidis / Q000187:drug effects
D015378:Imipenem; D002443:Ceftriaxone; D002438:Cefoperazone