New cadinene sesquiterpenoids from the Formosan soft coral Xenia puerto-galerae.
Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia puerto-galerae. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
Duh
Chang-Yih
CY
Department of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan. yihduh@mail.nsysu.edu.tw
Chien
Shih-Chao
SC
Song
Pei-Ying
PY
Wang
Shang-Kwei
SK
El-Gamal
Ali Ali H
AA
Dai
Chang-Feng
CF
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003110:Colonic Neoplasms; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D007941:Leukemia P388; D008175:Lung Neoplasms; D008752:Methylene Chloride; D051379:Mice; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013624:Taiwan; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000970:Antineoplastic Agents; D012717:Sesquiterpenes; D008752:Methylene Chloride