[Effects of bacterial protective liquid on radiation biology effect of mouse bone marrow cells].
To study the relationship between bacterial protective liquid (BPL) and the biological effect of mouse bone marrow cells by gamma-ray irradiation, apoptosis and the number of CD4+, CD8+ and NK cells were analyzed by flow cytometry(FCM), the results showed that BPL decreased the apoptosis and increased the proliferation of cells(P < 0.01). The theorem of action was related with raising the percentage vitality of NK cells and the quantity of CD4+ and CD8+. This study proved that BPL might have protective effect against radiation injury.
Xu
S
S
Institute of Military Medicine Chinese PLA, Shijiazhuang 050081, China.
Zhang
F
F
Wang
C
C
Wang
Z
Z
D000818:Animals; D017209:Apoptosis / Q000528:radiation effects*; D001406:Bacillaceae; D001854:Bone Marrow Cells / Q000528:radiation effects*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D003037:Cobalt Radioisotopes; D005260:Female; D005434:Flow Cytometry; D005720:Gamma Rays; D006711:Homocystine; D007694:Killer Cells, Natural / Q000276:immunology; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000276:immunology / Q000473:pathology*; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D011897:Random Allocation
D003037:Cobalt Radioisotopes; D011837:Radiation-Protective Agents; D006711:Homocystine