[Significance of the operational test parameters in selection of a diagnostic test for Helicobacter infection].
The group of 89 patients was examined, 63 of them suffered by a duodenal ulcerative disease, 11--by gastric ulcerative disease and 15--by chronic gastritis. It was conducted the comparison of the following indices: sensitivity, specificity, relationship of probability and diagnostic efficiency of histological, cytological methods, urease and respiratory tests, method of polymerase chain reaction, qualitative and quantitative definition of antibodies of the class IgG in serum blood to H. pylori by a method of enzyme immunoassay and Western-blot for H. pylori infection diagnostics was carried out. The results show that in choice of a diagnostic method of infection H. pylori it is better to use such characteristics as sensitivity and specificity, which more objectively reflect the diagnostic possibilities of each test.
Kishkun
A A
AA
Medical Centre of Bank of Russia, Moscow.
Sadokov
V M
VM
Arsenin
S L
SL
Budzinskiĭ
A A
AA
Klimkova
M A
MA
Kuchin
G A
GA
Gavrilova
G I
GI
D000907:Antibodies, Bacterial / Q000097:blood; D001431:Bacteriological Techniques / Q000379:methods; D001944:Breath Tests; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000382:microbiology*; D005756:Gastritis / Q000382:microbiology*; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D013276:Stomach Ulcer / Q000382:microbiology*; D014510:Urease
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D014510:Urease