[Cyanotic heart disease in the adult].
Patients with cyanotic heart disease may have an acceptable quality of life but are exposed to several complications: polycythaemia, often beneficial but with its risks: hyperviscosity, hyperuricaemia, thrombocytopaenia, blood clotting abnormalities; and the other complications of right-to-left shunt: cerebral abscess, cerebral embolism, endocarditis. The hypoxia may be improved by interventional catheterisation or palliative surgery. The Eisenmenger syndrome is life-threatening in pregnancy or during general anaesthesia. These patients are at risk and sometimes have iatrogenic complications, so usual cardiological treatment may be dangerous: diuretics, ACE inhibitors, oral anticoagulants, antiarrhythmics.
Iserin
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Services de cardiologie pédiatrique du Pr Sidi et de cardiologie adulte du Pr Desnos, hôpital Necker-Enfants malades, Paris.
D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000009:adverse effects; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use; D003490:Cyanosis / Q000209:etiology / Q000503:physiopathology; D004232:Diuretics / Q000627:therapeutic use; D004541:Eisenmenger Complex / Q000150:complications; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D000860:Hypoxia; D008875:Middle Aged; D010166:Palliative Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology; D011379:Prognosis; D012307:Risk Factors; D013577:Syndrome
D000806:Angiotensin-Converting Enzyme Inhibitors; D000889:Anti-Arrhythmia Agents; D000925:Anticoagulants; D004232:Diuretics