Donor eggs and brother's sperm: creating genetic likeness in the conceptus of an unmarried menopausal woman.
A 51-year old woman desiring to have a child with genetic similarity to herself chose to undergo egg donation using her brother's spermatozoa. Following careful screening of all participants, in-vitro fertilization and embryo transfer was accomplished. The patient failed to become pregnant, but a subsequent embryo transfer using cryopreserved embryos obtained during the initial attempt successfully resulted in a singleton pregnancy. Although rarely requested, under certain circumstances, the choice of a brother as a designated sperm donor, may be reasonable, allowing a woman who would otherwise have no genetic likeness to the child, a chance for motherhood.
Sauer
Mark V
MV
Department of Obstetrics & Gynecology, Division of Reproductive Endocrinology, College of Physicians & Surgeons, Columbia University, New York, New York.