title: Safety and efficacy of a new oral contraceptive containing drospirenone.
abstract: An oral contraceptive containing ethinyl estradiol and the unique progestin drospirenone provides a new contraceptive option. Ethinyl estradiol is the form of synthetic estrogen used in most oral contraceptives. Drospirenone differs from other synthetic progestins in that it is derived from 17 alpha-spirolactone and is an analogue of spironolactone. The oral contraceptive containing ethinyl estradiol and the unique progestin drospirenone has been shown to be highly efficacious and to provide safety equivalent to that of other oral contraceptive formulations.
authors.affiliation: Division of Reproductive Genetics, Department of Obstetrics and Gynecology, University of Illinois at Chicago, 820 South Wood Street, M/C 808, Chicago, IL 60612-7313, USA.
authors.forename: Lee P
authors.initials: LP
authors.lastname: Shulman
mesh_terms: D000736:Androstenes / Q000008:administration & dosage / Q000009:adverse effects; D001835:Body Weight; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects; D004997:Ethinyl Estradiol / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D011247:Pregnancy; D045167:Progesterone Congeners / Q000008:administration & dosage / Q000009:adverse effects; D016032:Randomized Controlled Trials as Topic
chemical_list: D000736:Androstenes; D003277:Contraceptives, Oral, Combined; D045167:Progesterone Congeners; D004997:Ethinyl Estradiol; C035144:drospirenone