title: Recurrent crepitant cellulitis caused by Clostridium perfringens.
abstract: A previously healthy 13-year-old boy developed extensive subcutaneous emphysema of the lower limb after a penetrating injury to the knee. Clostridium perfringens was isolated from the wound. Despite surgical debridement and appropriate antibiotics, the emphysema recurred, and prolonged antibiotic treatment was required. This case highlights the distinction between gas gangrene and the lesser known entity of clostridial crepitant cellulitis.
authors.affiliation: Paediatric Infectious Disease Unit, Department of General Medicine, Royal Children's Hospital, Victoria, Australia.
authors.forename: Penelope
authors.initials: P
authors.lastname: Bryant
authors.forename: Jonathan
authors.initials: J
authors.lastname: Carapetis
authors.forename: Jan
authors.initials: J
authors.lastname: Matussek
authors.forename: Nigel
authors.initials: N
authors.lastname: Curtis
mesh_terms: D000293:Adolescent; D002481:Cellulitis / Q000000981:diagnostic imaging / Q000382:microbiology*; D003016:Clostridium perfringens / Q000302:isolation & purification*; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D005738:Gas Gangrene / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods; D007262:Infusions, Intravenous; D007718:Knee Injuries / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology*; D008297:Male; D010406:Penicillins / Q000008:administration & dosage; D011859:Radiography; D012008:Recurrence; D018570:Risk Assessment; D013352:Subcutaneous Emphysema / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D016896:Treatment Outcome; D014950:Wounds, Penetrating / Q000150:complications
chemical_list: D010406:Penicillins