[Analysis of the allele polymorphism of (CTG)n and (GAG)n triplet repeats in DM, DRPLA, and SCA1 genes in various populations of Russia].
Polymorphism of highly polymorphic triplet repeats CTG of the 3'-untranslated region of the myotonin protein kinase gene and CAG of the genes associated with dentatorobral-pallidoluysian atrophy (DRPLA, or Hew River syndrome) and spinocerebellar ataxia type 1 (SCA1) was analyzed in several ethnic populations of Russia. A difference in allele spectra of the three genes was demonstrated for populations differing in ethnic origin.
Popova
S N
SN
Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182 Russia.
Slominskiĭ
P A
PA
Galushkin
S N
SN
Tarskaia
L A
LA
Spitsyn
V A
VA
Guseva
I A
IA
Limborskaia
S A
SA
D020413:3' Untranslated Regions; D000483:Alleles; D000067696:Ataxin-1; D000067528:Ataxins; D005828:Genetics, Population; D006801:Humans; D065636:Myotonin-Protein Kinase; D009419:Nerve Tissue Proteins / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D011110:Polymorphism, Genetic; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D012800:Siberia / Q000208:ethnology; D018911:Trinucleotide Repeats
D020413:3' Untranslated Regions; C000593749:ATXN1 protein, human; D000067696:Ataxin-1; D000067528:Ataxins; C585517:DMPK protein, human; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; C095278:atrophin-1; D065636:Myotonin-Protein Kinase; D017346:Protein Serine-Threonine Kinases