title: Fluorosis development in seven age cohorts after an 11-month break in water fluoridation.
abstract: This study used an 11-month break in water fluoridation to identify the time when developing incisors are most sensitive to fluorosis development. The study was based in Durham, NC, where an interruption to water fluoridation occurred between September, 1990, and August, 1991. A total of 1896 children was dentally examined. Fluorosis was measured by the TF index, and parents or guardians completed a questionnaire on demographics and fluoride history. Age cohorts ranged from those born 5 years before the break, to those born 1 year after the resumption of fluoridation. Fluorosis prevalence for seven age cohorts whose birth years ranged from 1985-86 to 1991-92 was 57.1, 62.3, 33.0, 32.3, 39.8, 30.2, and 36.8%, respectively. Children aged from birth to 3 years at the break, and those born 1 year after it, had less fluorosis than those aged 4-5 years at the break.
authors.affiliation: Department of Epidemiology, School of Public Health, University of Michigan, 109 Observatory Street, Ann Arbor, MI 48109-2029, USA. bburt@umich.edu
authors.forename: B A
authors.initials: BA
authors.lastname: Burt
authors.forename: M A
authors.initials: MA
authors.lastname: Keels
authors.forename: K E
authors.initials: KE
authors.lastname: Heller
mesh_terms: D002327:Cariostatic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D005457:Fluoridation; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use; D009050:Fluorosis, Dental / Q000145:classification / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000473:pathology; D007223:Infant; D016015:Logistic Models; D008297:Male; D009067:Mouthwashes / Q000627:therapeutic use; D015999:Multivariate Analysis; D009657:North Carolina; D015588:Observer Variation; D016017:Odds Ratio; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D014099:Toothbrushing; D014100:Toothpastes / Q000627:therapeutic use
chemical_list: D002327:Cariostatic Agents; D009067:Mouthwashes; D014100:Toothpastes; D005459:Fluorides