[Inhibitory activity of Dianthus superbus L. and 11 kinds of diuretic Traditional Chinese medicines for urogenital Chlamydia trachomatis in vitro].
OBJECTIVE
To detect the susceptibility of urogenital chlamydia trachomatis(CT) to 12 kinds of diuretic traditional Chinese medicines.


METHODS
The inhibitory activity of these medicines for CT was detected by microculture technique of McCoy cell in vitro.


RESULTS
All the 12 kinds of diuretic traditional Chinese medicines had inhibitory activities for urogenital CT, with minimal inhibitory concentrations (MICs) from 0.122 mg.ml-1 to 62.5 mg.ml-1. The activities of Dianthus superbus L., Poria cocos(Shcw.) Woft, Polyporus umbellatus and Artemissia capillaris were stronger. The number and volume of CT inclusions reduced gradually and disappeared finally with the rise of concentration.


CONCLUSIONS
All the 12 kinds of diuretic traditional Chinese medicines possess some inhibitory activity for urogenital CT.
Li
J J
JJ
Department of Dermatology, First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, Guangdong, China.
Tu
Y Y
YY
Tong
J Z
JZ
Wang
P T
PT
D019306:Artemisia / Q000737:chemistry; D002690:Chlamydia Infections / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000187:drug effects* / Q000302:isolation & purification; D029749:Dianthus / Q000737:chemistry*; D004232:Diuretics / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D052776:Female Urogenital Diseases / Q000382:microbiology; D006801:Humans; D052801:Male Urogenital Diseases; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*
D004232:Diuretics; D004365:Drugs, Chinese Herbal