title: Human cutaneous leishmaniasis due to Leishmania infantum in the Sidi Bourouis focus (Northern Tunisia): epidemiological study and isoenzymatic characterization of the parasites.
abstract: The authors report an increase of the number of case of cutaneous leishmaniasis in the Sidi Bourouis region community of Siliana Governorate (Tunisia), with 38 cases diagnosed in 6 months (1st November 2000-30th April 2001), contrary to its usual sporadic character. The isoenzymatic identification of 15 isolated strains emphasizes the role of the Leishmania infantum zymodeme MON-1 as an important factor in the genesis of the sporadic cutaneous leishmaniasis of Northern Tunisia. In fact it was isolated in 6 cases while L. infantum MON-24, the usual agent was isolated in 9 cases.
authors.affiliation: Laboratoire de Parasitologie-Mycologie, Hôpital La Rabta, 1007 Tunis, Tunisia. emna.chaker@rns.tn
authors.forename: S
authors.initials: S
authors.lastname: Belhadj
authors.forename: F
authors.initials: F
authors.lastname: Pratlong
authors.forename: M
authors.initials: M
authors.lastname: Hammami
authors.forename: K
authors.initials: K
authors.lastname: Kallel
authors.forename: J P
authors.initials: JP
authors.lastname: Dedet
authors.forename: E
authors.initials: E
authors.lastname: Chaker
mesh_terms: D000368:Aged; D000818:Animals; D002478:Cells, Cultured; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000032:analysis*; D018314:Leishmania infantum / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology*; D008297:Male; D008536:Meglumine / Q000494:pharmacology / Q000627:therapeutic use; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds / Q000494:pharmacology / Q000627:therapeutic use; D014416:Tunisia / Q000453:epidemiology
chemical_list: D007527:Isoenzymes; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate