Three 2-aminopurine derivatives.
The structure of 2-amino-6-chloropurine, C(5)H(4)ClN(5), (I), comprises a flat molecule, with all possible strong hydrogen-bond donors and acceptors involved in the hydrogen-bonding network. The structures of 2-amino-6-(4-chlorophenylsulfanyl)purine hemihydrate, C(11)H(8)ClN(5)S.0.5H(2)O, (II), and 2-amino-6-(4-methylphenylsulfanyl)purine 0.33-hydrate, C(12)H(11)N(5)S.0.33H(2)O, (III), have two and three unique molecules, respectively, and one water molecule in their asymmetric units. Both (II) and (III) exhibit elaborate hydrogen-bonding networks that involve the S (for both) and Cl [for (II)] atoms in addition to the expected strong hydrogen-bonding sites. Both structures also have offset-stacking formations of the phenyl and purine rings.
Lynch
Daniel E
DE
School of Science and the Environment, Coventry University, Coventry CV1 5FB, England. apx106@coventry.ac.uk
McClenaghan
Ian
I
D015075:2-Aminopurine / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D015394:Molecular Structure
D015075:2-Aminopurine