title: Antimicrobial resistance of Escherichia coli O26, O103, O111, O128, and O145 from animals and humans.
abstract: Susceptibilities to fourteen antimicrobial agents important in clinical medicine and agriculture were determined for 752 Escherichia coli isolates of serotypes O26, O103, O111, O128, and O145. Strains of these serotypes may cause urinary tract and enteric infections in humans and have been implicated in infections with Shiga toxin-producing E. coli (STEC). Approximately 50% of the 137 isolates from humans were resistant to ampicillin, sulfamethoxazole, cephalothin, tetracycline, or streptomycin, and approximately 25% were resistant to chloramphenicol, trimethoprim-sulfamethoxazole, or amoxicillin-clavulanic acid. Approximately 50% of the 534 isolates from food animals were resistant to sulfamethoxazole, tetracycline, or streptomycin. Of 195 isolates with STEC-related virulence genes, approximately 40% were resistant to sulfamethoxazole, tetracycline, or streptomycin. Findings from this study suggest antimicrobial resistance is widespread among E. coli O26, O103, O111, O128, and O145 inhabiting humans and food animals.
authors.affiliation: University of Maryland, College Park, USA.
authors.forename: Carl M
authors.initials: CM
authors.lastname: Schroeder
authors.forename: Jianghong
authors.initials: J
authors.lastname: Meng
authors.forename: Shaohua
authors.initials: S
authors.lastname: Zhao
authors.forename: Chitrita
authors.initials: C
authors.lastname: DebRoy
authors.forename: Jocelyn
authors.initials: J
authors.lastname: Torcolini
authors.forename: Cuiwei
authors.initials: C
authors.lastname: Zhao
authors.forename: Patrick F
authors.initials: PF
authors.lastname: McDermott
authors.forename: David D
authors.initials: DD
authors.lastname: Wagner
authors.forename: Robert D
authors.initials: RD
authors.lastname: Walker
authors.forename: David G
authors.initials: DG
authors.lastname: White
mesh_terms: D000818:Animals; D024881:Drug Resistance, Bacterial; D019453:Escherichia coli O157 / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D012703:Serotyping