title: The relative impact of local and endogenous patient-related factors on implant failure up to the abutment stage.
abstract: The aim of the present study was to assess the influence of endogenous and local factors on the occurrence of implant failure up to the abutment stage. The study comprised a group of 399 consecutive patients, which represented the total of patients who had been treated from 1995 to 1997 (with a total of 1263 Brånemark Brån-system implants) at the Department of Periodontology of the University Hospital, Catholic University Leuven. For each patient, the medical history was carefully examined. Data collection and analysis were mainly focused on endogenous factors such as hypertension, osteoporosis, hypo- or hyperthyroid function, chemotherapy, diabetes type I or II, Crohn's disease, some local factors (e.g. bone quality, reason for tooth loss) and breach of sterility during surgery. The reason for tooth loss, smoking habits, radiotherapy and other local bone factors (bone quality and quantity) were also recorded. Implant failures were recorded up to the abutment connection. The present study indicated a success rate until this stage of 97.8%. General factors such as heavy smoking, chemotherapy plus poor bone quality increased implant failure rate. Radiotherapy, limited bone volume and claustrophobia, which led to breaching the strict preoperative rules of asepsis, appeared to be the most relevant local factors for early implant failures.
authors.affiliation: Department of Periodontology, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University Leuven, Leuven, Belgium. Daniel.vanSteenberghe@uz.kuleuven.ac.be
authors.forename: Daniel
authors.initials: D
authors.lastname: van Steenberghe
authors.forename: Reinhilde
authors.initials: R
authors.lastname: Jacobs
authors.forename: Mandy
authors.initials: M
authors.lastname: Desnyder
authors.forename: Gaia
authors.initials: G
authors.lastname: Maffei
authors.forename: Marc
authors.initials: M
authors.lastname: Quirynen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density / Q000502:physiology; D001862:Bone Resorption / Q000150:complications; D016009:Chi-Square Distribution; D003424:Crohn Disease / Q000150:complications; D000044:Dental Abutments; D015921:Dental Implants; D017267:Dental Prosthesis Design; D019232:Dental Restoration Failure; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D006980:Hyperthyroidism / Q000150:complications; D007037:Hypothyroidism / Q000150:complications; D007571:Jaw Diseases / Q000150:complications; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications; D011878:Radiotherapy / Q000009:adverse effects; D012907:Smoking / Q000009:adverse effects; D013223:Statistics as Topic; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants