title: Effect of Lepidium meyenii (Maca), a root with aphrodisiac and fertility-enhancing properties, on serum reproductive hormone levels in adult healthy men.
abstract: Lepidium meyenii (Maca) is a Peruvian hypocotyl that grows exclusively between 4000 and 4500 m in the central Andes. Maca is traditionally employed in the Andean region for its supposed aphrodisiac and/or fertility-enhancing properties. This study was a 12-week double-blind, placebo-controlled, randomized, parallel trial in which active treatment with different doses of Maca Gelatinizada was compared with a placebo. The study aimed to test the hypothesis that Maca has no effect on serum reproductive hormone levels in apparently healthy men when administered in doses used for aphrodisiac and/or fertility-enhancing properties. Men aged between 21 and 56 Years received 1500 mg or 3000 mg Maca. Serum levels of luteinizing hormone, follicle-stimulating hormone, prolactin, 17-alpha hydroxyprogesterone, testosterone and 17-beta estradiol were measured before and at 2, 4, 8 and 12 weeks of treatment with placebo or Maca (1.5 g or 3.0 g per day). Data showed that compared with placebo Maca had no effect on any of the hormones studied nor did the hormones show any changes over time. Multiple regression analysis showed that serum testosterone levels were not affected by treatment with Maca at any of the times studied (P, not significant). In conclusion, treatment with Maca does not affect serum reproductive hormone levels.
authors.affiliation: Instituto de Investigaciones de la Altura, and Department of Biological and Physiological Sciences (Faculty of Sciences and Philosophy), Universidad Peruana Cayetano Heredia, PO 1843, Lima, Peru.
authors.forename: G F
authors.initials: GF
authors.lastname: Gonzales
authors.forename: A
authors.initials: A
authors.lastname: Córdova
authors.forename: K
authors.initials: K
authors.lastname: Vega
authors.forename: A
authors.initials: A
authors.lastname: Chung
authors.forename: A
authors.initials: A
authors.lastname: Villena
authors.forename: C
authors.initials: C
authors.lastname: Góñez
mesh_terms: D019326:17-alpha-Hydroxyprogesterone / Q000097:blood; D000328:Adult; D001046:Aphrodisiacs / Q000494:pharmacology*; D004311:Double-Blind Method; D004958:Estradiol / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D029686:Lepidium; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010568:Peru; D018517:Plant Roots; D011388:Prolactin / Q000097:blood; D012044:Regression Analysis; D013739:Testosterone / Q000097:blood
chemical_list: D001046:Aphrodisiacs; D012739:Gonadal Steroid Hormones; D013739:Testosterone; D004958:Estradiol; D019326:17-alpha-Hydroxyprogesterone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone