title: Trends in selenium biochemistry.
abstract: The biochemistry of selenium-containing natural products, including selenoproteins, is reviewed up to May 2002. Particular emphasis is placed on the assimilation of selenium from inorganic and organic selenium sources for selenoprotein synthesis, the catalytic role of selenium in enzymes, and medical implications of an unbalanced selenium supply. The review contains 393 references on key discoveries and recent progress.
authors.affiliation: Dept. of Vitamins and Atherosclerosis, German Institute of Human Nutrition, Arthur-Scheunert-Allee 114-116, D-14558 Bergholz-Rehbrücke, Germany.
authors.forename: Marc
authors.initials: M
authors.lastname: Birringer
authors.forename: Sandra
authors.initials: S
authors.lastname: Pilawa
authors.forename: Leopold
authors.initials: L
authors.lastname: Flohé
mesh_terms: D001419:Bacteria / Q000737:chemistry; D001483:Base Sequence; D001669:Biochemical Phenomena; D001671:Biochemistry; D001685:Biological Factors / Q000737:chemistry*; D002384:Catalysis; D004798:Enzymes / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D012343:RNA, Transfer / Q000737:chemistry / Q000235:genetics; D012643:Selenium / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology; D051140:Selenoproteins
chemical_list: D001685:Biological Factors; D004798:Enzymes; D011506:Proteins; D051140:Selenoproteins; D012343:RNA, Transfer; D012643:Selenium