title: Apoptosis. Life and death decisions.
authors.affiliation: Merck Frosst Centre for Therapeutic Research, Merck Research Laboratories, Montreal, Quebec HLH 3LI, Canada.
authors.forename: Donald W
authors.initials: DW
authors.lastname: Nicholson
authors.forename: Nancy A
authors.initials: NA
authors.lastname: Thornberry
mesh_terms: D017209:Apoptosis; D053148:Caspase 3; D053453:Caspase 9; D020169:Caspases / Q000378:metabolism; D002471:Cell Transformation, Neoplastic; D004789:Enzyme Activation; D006801:Humans; D008928:Mitochondria / Q000378:metabolism*; D009369:Neoplasms / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D011498:Protein Precursors / Q000378:metabolism*; D011725:Pyridines / Q000494:pharmacology*; D034622:RNA Interference; D013947:Thymosin / Q000031:analogs & derivatives* / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000378:metabolism*
chemical_list: D011498:Protein Precursors; D011725:Pyridines; D025521:Tumor Suppressor Proteins; C470638:alpha-(trichloromethyl)-4-pyridineethanol; C040782:prothymosin alpha; D013947:Thymosin; C505407:CASP3 protein, human; C506433:CASP9 protein, human; D053148:Caspase 3; D053453:Caspase 9; D020169:Caspases