title: [Chronic diarrhea: pathogenesis and therapy].
abstract: Periodical diarrhea is one of the steadiest symptoms of chronic bowels diseases. This term defines an increase of stool frequency (over three times a day) with the excretion of greater amount and more liquid consistency of excrements as compared to usual bowels emptying of the given individual. Diarrhea is considered to be chronic if its duration is over 30 days. Pathogenetic mechanisms of formation and development of chronic diarrheas have a lot in common. As a result, any diarrhea is a clinical manifestation of a disorder of water and electrolytes transportation in the digestive tract. Such disorders appear due to indigestion, absorption and secretion disorders. At that the small intestine and large intestine should be considered as a single physiological unit.
authors.affiliation: Central Scientific Research Institute of Gastroenterology, Moscow.
authors.forename: L M
authors.initials: LM
authors.lastname: Krums
mesh_terms: D001419:Bacteria / Q000254:growth & development; D001647:Bile Acids and Salts / Q000378:metabolism; D002908:Chronic Disease; D003967:Diarrhea / Q000178:diet therapy / Q000209:etiology* / Q000628:therapy*; D016061:Enterosorption; D057487:Enzyme Therapy; D005122:Exudates and Transudates; D005772:Gastrointestinal Transit / Q000187:drug effects; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism; D007422:Intestines / Q000382:microbiology; D010528:Peristalsis / Q000187:drug effects; D019936:Probiotics / Q000627:therapeutic use
chemical_list: D001647:Bile Acids and Salts