Bimodal oscillations in nephron autoregulation.
The individual functional unit of the kidney (the nephron) displays oscillations in its pressure and flow regulation at two different time scales: fast oscillations associated with a myogenic dynamics of the afferent arteriole, and slower oscillations arising from a delay in the tubuloglomerular feedback. We investigate the intra- and internephron entrainment of the two time scales. In addition to full synchronization, both wavelet analyses of experimental data and numerical simulations reveal a partial entrainment in which neighboring nephrons attain a state of chaotic synchronization with respect to their slow dynamics, but the fast dynamics remain desynchronized.
Sosnovtseva
O V
OV
Physics Department, Saratov State University, Astrakhanskaya Street 83, Saratov, 410026, Russia.
Pavlov
A N
AN
Mosekilde
E
E
Holstein-Rathlou
N-H
NH