[Studies on chemical constituents of leaves of Salix matsudana Koidz and their influence on lipolysis].
OBJECTIVE
To study the chemical constituents of the leaves Salix matsudana and their influence on norepinephrine-induced lipolysis.


METHODS
The chemical constituents were studied by means of chemical methods and spectral analysis. Rat's epididymal lipocytes were used to observe the effect of these constituents on the lipolysis promoted by norepinephrine (NE).


RESULTS
Three constituents were isolated from the leaves of S. matsudana, and identified as apigenin-7-O-beta-D-glucopyranoside, luteolin-7-O-beta-D-glucopyranoside, luteolin-3'-methyl ether-7-O-beta-D-glucopyranoside, of which two can increase the release of free fatty acids(FFA) in the process lipolysis promoted by NE.


CONCLUSIONS
All the three constituents were isolated from the leaves of Salix spp. for the first time.
Zhang
J
J
Chinese Medical Material Collge of Jilin Agricultural University, Changchun 130118, Jinin, China.
Zhang
Y N
YN
Han
L K
LK
D017667:Adipocytes / Q000187:drug effects; D000818:Animals; D047310:Apigenin; D004822:Epididymis / Q000166:cytology; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D005960:Glucosides / Q000302:isolation & purification / Q000494:pharmacology; D008066:Lipolysis / Q000187:drug effects*; D047311:Luteolin; D008297:Male; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D032108:Salix / Q000737:chemistry*; D014197:Trees / Q000737:chemistry
D005419:Flavonoids; D005960:Glucosides; C057792:apigetrin; D047310:Apigenin; C066408:luteolin-7-glucoside; D047311:Luteolin