Medulloblastoma in mice lacking p53 and PARP: all roads lead to Gli.
Eberhart
Charles G
CG
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. ceberha@jhmi.edu
D017668:Age of Onset; D000818:Animals; D002531:Cerebellum / Q000166:cytology / Q000196:embryology; D004195:Disease Models, Animal; D020022:Genetic Predisposition to Disease; D053823:Hedgehog Proteins; D006801:Humans; D008527:Medulloblastoma / Q000235:genetics* / Q000378:metabolism*; D008565:Membrane Proteins / Q000172:deficiency / Q000235:genetics; D051379:Mice; D018345:Mice, Knockout; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics; D018242:Neuroectodermal Tumors, Primitive / Q000235:genetics; D015513:Oncogene Proteins / Q000378:metabolism*; D000072079:Patched Receptors; D011065:Poly(ADP-ribose) Polymerases / Q000172:deficiency* / Q000235:genetics; D011956:Receptors, Cell Surface; D015398:Signal Transduction; D015534:Trans-Activators / Q000235:genetics; D014157:Transcription Factors / Q000378:metabolism*; D016159:Tumor Suppressor Protein p53 / Q000172:deficiency* / Q000235:genetics; D015854:Up-Regulation; D000071676:Zinc Finger Protein GLI1
D053823:Hedgehog Proteins; D008565:Membrane Proteins; D015513:Oncogene Proteins; D000072079:Patched Receptors; D011956:Receptors, Cell Surface; D015534:Trans-Activators; D014157:Transcription Factors; D016159:Tumor Suppressor Protein p53; D000071676:Zinc Finger Protein GLI1; D011065:Poly(ADP-ribose) Polymerases