Brosimacutins A-I, nine new flavonoids from Brosimum acutifolium.
Nine new flavonoids, brosimacutins A-I (1-9), and four known flavonoids were isolated from the bark of Brosimum acutifolium, a Brazilian folk medicine ("Mururé"). Their structures were elucidated by spectroscopic methods, including 2D NMR. Brosimacutins A-I possess differentially functionalized isoprene units at C-8.
Takashima
Junko
J
Research and Development Division, Mitsubishi Pharma Corporation, Kamoshida-cho, Aoba-ku, Yokohama 227-0033, Japan. Takashima.Junko@me.m-pharma.co.jp
Ohsaki
Ayumi
A
D001938:Brazil; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D008519:Medicine, Traditional; D008968:Molecular Conformation; D015394:Molecular Structure; D029586:Moraceae / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D013329:Structure-Activity Relationship
D005419:Flavonoids