Delayed onset of malignant hyperthermia in desflurane anesthesia.
Animal-experimental studies demonstrate desflurane's trigger effect for malignant hyperthermia (MH). In contrast to other anesthetics, the time interval from exposure to the occurrence of symptoms is much longer with desflurane. This case report focuses on MH induced by desflurane alone.
Hoenemann
Christian W
CW
Department of Anesthesiology and Critical CareUniversitätsklinikum Münster, Germany. hoenemann@anit.uni-muester.de
Halene-Holtgraeve
Tobias B
TB
Booke
Michael
M
Hinder
Frank
F
Daudel
Fritz
F
Reich
Alexander
A
Van Aken
Hugo
H
D000293:Adolescent; D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D001706:Biopsy; D003620:Dantrolene / Q000627:therapeutic use; D000077335:Desflurane; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D007530:Isoflurane / Q000009:adverse effects* / Q000031:analogs & derivatives*; D008305:Malignant Hyperthermia / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D016343:Monitoring, Intraoperative; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D018482:Muscle, Skeletal / Q000187:drug effects; D019637:Orthopedic Procedures; D011184:Postoperative Period; D012600:Scoliosis / Q000601:surgery
D018685:Anesthetics, Inhalation; D009125:Muscle Relaxants, Central; D000077335:Desflurane; D007530:Isoflurane; D003620:Dantrolene