title: Acute renal failure and hearing loss due to sodium bromate poisoning: a case report and review of the literature.
abstract: Acute renal failure with hearing loss due to sodium bromate intoxication is described. A 48-year-old woman who ingested permanent wave neutralizer in a suicide attempt and developed anuria was admitted to our hospital for hemodialysis. Bromate intoxication was suspected and hemodialysis was carried out; she required maintenance dialysis 3 times a week. Irreversible severe sensorineural hearing loss continued and peripheral polyneuropathy developed in the lower limbs. We measured the concentration of bromine in the serum before and after the first hemodialysis and found its removal rate to be 61.3%. This is the first report that proved the utility of hemodialysis for bromate intoxication in a clinical setting.
authors.affiliation: San-ai Memorial Hospital, Chiba, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Sashiyama
authors.forename: Y
authors.initials: Y
authors.lastname: Irie
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtake
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: H
authors.initials: H
authors.lastname: Yoshida
authors.forename: T
authors.initials: T
authors.lastname: Sakai
authors.forename: K
authors.initials: K
authors.lastname: Okuda
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000628:therapy; D001959:Bromates / Q000506:poisoning*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D006435:Renal Dialysis; D017670:Sodium Compounds / Q000506:poisoning*; D013406:Suicide, Attempted
chemical_list: D001959:Bromates; D017670:Sodium Compounds; C060553:sodium bromate