Nephrogenic fibrosing dermopathy (scleromyxedema-like illness of renal disease).
Nephrogenic fibrosing dermopathy or scleromyxedema-like illness of renal disease is a recently reported disorder. It manifests as scleromyxedema-like skin lesions without associated paraproteinemia, occurring in the setting of renal disease. In the majority of cases skin lesions of nephrogenic fibrosing dermopathy develop after hemodialysis or renal transplantation; however, the origin is still unknown. We report 4 new cases of nephrogenic fibrosing dermopathy and review the literature. The clinical and histopathologic features, differential diagnosis, possible etiology, and treatment options are reviewed.
Mackay-Wiggan
Julian M
JM
Department of Dermatology; Division of Nephrology, Columbia University, New York, New York, USA.
Cohen
David J
DJ
Hardy
Mark A
MA
Knobler
Elizabeth H
EH
Grossman
Marc E
ME
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005355:Fibrosis; D006801:Humans; D007674:Kidney Diseases / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009230:Myxedema / Q000209:etiology; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology