Efficient and regioselective synthesis of functionalized pyrroles by cyclocondensation of 1,3-dicarbonyl dianions with alpha-azidoketones.
The cyclocondensation of 1,3-dicarbonyl dianions with alpha-azidoketones regioselectively afforded 2-alkylidenepyrrolidines which were transformed into functionalized pyrroles by treatment with acid.
Langer
Peter
P
Institut für Chemie und Biochemie der Ernst-Moritz-Arndt-Universität Greifswald, Soldmannstr. 16, D-17487 Greifswald, Germany. peter.langer@uni-greifswald.de
Freifeld
Ilia
I