title: The sarcoplasmic reticulum: its discovery and rediscovery.
abstract: In 1902, Emilio Veratti made the most accurate description, by light microscopy, of a reticular structure in the sarcoplasm. However, this structure was almost lost to man's knowledge for more than 50 years and was rediscovered during the 1960s, following the introduction of electron microscopy. Since then, biochemistry, electron microscopy and electrophysiology have unravelled the crucial role of the sarcoplasmic reticulum in the control of muscle contraction.
authors.affiliation: Department of Experimental Medicine, University of Pavia, 10 Piazza Botta, 27100, Pavia, Italy. mazzarello@igm.cnr.it
authors.forename: Paolo
authors.initials: P
authors.lastname: Mazzarello
authors.forename: Alberto
authors.initials: A
authors.lastname: Calligaro
authors.forename: Vanio
authors.initials: V
authors.lastname: Vannini
authors.forename: Umberto
authors.initials: U
authors.lastname: Muscatello
mesh_terms: D000715:Anatomy / Q000266:history*; D001695:Biology / Q000266:history*; D049672:History, 19th Century; D049673:History, 20th Century; D007558:Italy; D012519:Sarcoplasmic Reticulum; D013030:Spain