Genetic engineering of a recombinant fusion protein possessing an antitumor antibody fragment and a TNF-alpha moiety.
Xiang
Jim
J
Saskatoon Cancer Center, Departments of Microbiology and Oncology, University of Saskatchewan, Saskatoon, Canada.
Gordon
John R
JR
D000595:Amino Acid Sequence; D000818:Animals; D000906:Antibodies / Q000235:genetics*; D002846:Chromatography, Affinity / Q000379:methods; D003001:Cloning, Molecular / Q000379:methods*; D003601:Cytotoxicity Tests, Immunologic / Q000379:methods; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D011993:Recombinant Fusion Proteins / Q000235:genetics* / Q000302:isolation & purification; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics*
D000906:Antibodies; D011993:Recombinant Fusion Proteins; D014409:Tumor Necrosis Factor-alpha