Non-gonococcal urethritis due to Chlamydia trachomatis: the Ibadan experience.
Using a qualitative amplified enzyme-linked immunoassay, two hundred and eighty-nine male patients with symptoms and signs suggestive of urethritis were investigated for Chlamydia trachomatis as a cause of non-gonococcal urethritis (NGU). Ninety-one (31.49%) of the 289 male patients investigated had gonococcal urethritis whilst 198 (68.51%) had NGU out of which 112 (56.60%) had chlamydial urethritis and 14 (7.1%) had Trichomonal urethritis. Two (6.7%) of the control subjects had C. trachomatis in their urethral swabs. The difference in the occurrence of C. trachomatis between the patients and the controls was highly statistically significant (P<0.001). The age range of peak incidence among the patients investigated was 20-29 years. Thirteen of the men treated for gonorrhoea still had watery urethral discharge and irritation and were diagnosed as having post-gonococcal urethritis (PGU), eleven (84.6%) of whom had C. trachomatis demonstrated in their urethral swabs. We were able to demonstrate a significant difference in clinical symptoms in men with gonorrhoea and NGU but only a slight difference between men with chlamydia-positive NGU and chlamydia-negative NGU.
Bakare
R A
RA
Special Treatment Clinic, University College Hospital, Ibadan, Nigeria.
Oni
A A
AA
Umar
U S
US
Okesola
A O
AO
Kehinde
A O
AO
Fayemiwo
S A
SA
Fasina
N A
NA
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D016022:Case-Control Studies; D002648:Child; D002690:Chlamydia Infections; D002692:Chlamydia trachomatis; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006069:Gonorrhea / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D008297:Male; D017533:Marital Status / Q000706:statistics & numerical data; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D011159:Population Surveillance; D012307:Risk Factors; D012747:Sexual Partners; D014245:Trichomonas Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D014504:Urban Health / Q000706:statistics & numerical data; D014526:Urethritis / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*