Outcome for donors and recipients in two egg-sharing policies.
OBJECTIVE
To assess the effect of two different donation policies on results of egg-sharing.


METHODS
Retrospective analysis.


METHODS
Tertiary referral center.


METHODS
One hundred five donor-recipient pairs participating in an egg-sharing program between 1998 and 2001.


METHODS
Egg-sharing was performed according to policy A (retrieval of at least 12 oocytes, with more oocytes allocated to the donor) or policy B (retrieval of at least 8 oocytes, with equal distribution of oocytes between donors and recipients).


METHODS
Delivery rate and cycle cancellation rate.


RESULTS
Policy B resulted in a decreased cycle cancellation rate in the recipient group compared with policy A (9.7% vs. 29.7%, respectively; P<or=.01). No significant difference in delivery rate per fresh transfer was observed between policy A and policy B in donors (30.2% vs. 27.8%, respectively) or recipients (28.2% vs. 25.7%, respectively).


CONCLUSIONS
Decreasing the number of oocytes required to perform egg sharing from 12 to 8 and dividing the oocytes equally between donors and recipients significantly reduces the cycle cancellation rate while it does not appear to affect adversely the probability of delivery.
Kolibianakis
Efstratios M
EM
Center for Reproductive Medicine, Dutch-Speaking Brussels Free University, Brussels, Belgium. stratis@easynet.be
Tournaye
Herman
H
Osmanagaoglu
Kaan
K
Camus
Michel
M
Van Waesberghe
Linda
L
Van Steirteghem
Andre
A
Devroey
Paul
P
D000328:Adult; D002452:Cell Count; D015925:Cryopreservation; D046508:Culture Techniques; D036861:Delivery, Obstetric; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008875:Middle Aged; D018587:Oocyte Donation / Q000379:methods; D009865:Oocytes; D011247:Pregnancy; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic; D016896:Treatment Outcome