The ERGO genome analysis and discovery system.
The ERGO (http://ergo.integratedgenomics.com/ERGO/) genome analysis and discovery suite is an integration of biological data from genomics, biochemistry, high-throughput expression profiling, genetics and peer-reviewed journals to achieve a comprehensive analysis of genes and genomes. Far beyond any conventional systems that facilitate functional assignments, ERGO combines pattern-based analysis with comparative genomics by visualizing genes within the context of regulation, expression profiling, phylogenetic clusters, fusion events, networked cellular pathways and chromosomal neighborhoods of other functionally related genes. The result of this multifaceted approach is to provide an extensively curated database of the largest available integration of genomes, with a vast collection of reconstructed cellular pathways spanning all domains of life. Although access to ERGO is provided only under subscription, it is already widely used by the academic community. The current version of the system integrates 500 genomes from all domains of life in various levels of completion, 403 of which are available for subscription.
Overbeek
Ross
R
Integrated Genomics Inc., 2201 West Campbell Park Drive, Chicago, IL 60612, USA. ross@integratedgenomics.com
Larsen
Niels
N
Walunas
Theresa
T
D'Souza
Mark
M
Pusch
Gordon
G
Selkov
Eugene
E
Liolios
Konstantinos
K
Joukov
Viktor
V
Kaznadzey
Denis
D
Anderson
Iain
I
Bhattacharyya
Anamitra
A
Burd
Henry
H
Gardner
Warren
W
Hanke
Paul
P
Kapatral
Vinayak
V
Mikhailova
Natalia
N
Vasieva
Olga
O
Osterman
Andrei
A
Vonstein
Veronika
V
Fonstein
Michael
M
Ivanova
Natalia
N
Kyrpides
Nikos
N
D000818:Animals; D019295:Computational Biology; D030541:Databases, Genetic; D020869:Gene Expression Profiling; D016678:Genome; D023281:Genomics; D008660:Metabolism; D011506:Proteins / Q000502:physiology
D011506:Proteins