title: A recurrent case of odontogenic ghost cell tumour of the mandible.
abstract: Odontogenic ghost cell tumour (OGCT), also referred to as dentinogenic ghost cell tumour, is an extremely rare tumour classified as a neoplastic variant of calcifying ondontogenic cyst (COC). To date, only 13 cases of OGCT arising in the maxilla or mandible have been reported. We describe an OGCT that recurred after segmental resection of the mandible in a 59-year-old man. Histopathological examination revealed tumour invasion of the surrounding cortical bone, areas containing numerous calcifying flaky cell nests, and dentinoid matrix near epithelial cell nests. No atypical mitosis was found. There has been no evidence of recurrence or metastasis in the 4 years after operation.
authors.affiliation: Oral and Maxillofacial Surgery, Graduate School of Dental Medicine, Hokkaido University, Japan. kasahara@den.hokudai.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Kasahara
authors.forename: T
authors.initials: T
authors.lastname: Iizuka
authors.forename: I
authors.initials: I
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Totsuka
authors.forename: T
authors.initials: T
authors.lastname: Kohgo
mesh_terms: D003804:Dentin / Q000473:pathology; D004847:Epithelial Cells / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008339:Mandibular Neoplasms / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009808:Odontogenic Tumors / Q000473:pathology* / Q000601:surgery
chemical_list: D007633:Keratins