Continuous arterial infusion strategies using implanted ports.
Surgically implanted ports have been used in continuous or repetitive intra-arterial (IA) chemotherapeutic infusions for patients with multiple liver metastases from colorectal cancer. Recently, a percutaneous implantation procedure was developed, facilitating safe and less invasive IA infusions in the treatment of various disease conditions. This article focuses on the interventional techniques for percutaneous implantation of a vascular access device, consisting of an indwelling catheter and an implantable port, to perform IA infusions. Additionally, we describe details of the alteration of blood flow by coil-embolization that can be performed to obtain selective drug distribution to the target area and to avoid side effects caused by the administration of the chemotherapeutic agent into nontarget areas.
Ganaha
Fumikiyo
F
Department of Radiology, The Jikei University School of Medicine, Tokyo, Japan.
Sadaoka
Shunichi
S
Yamada
Tetsuhisa
T
D002408:Catheters, Indwelling; D015179:Colorectal Neoplasms / Q000473:pathology; D004621:Embolization, Therapeutic; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000295:instrumentation*; D008113:Liver Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000556:secondary; D011859:Radiography; D015642:Radiology, Interventional / Q000295:instrumentation