Synchronous renal cell carcinoma and gynecologic malignancies.
BACKGROUND
Synchronicity of renal cell carcinoma and gynecologic malignancies is a rare condition and standardized treatment does not exist.


METHODS
Three cases of synchronous renal cell carcinoma and gynecologic malignancies are described. All three cases underwent optimal cytoreductive surgery for the gynecologic malignancy and a radical nephrectomy for the renal cell carcinoma. Adjuvant treatment, after surgery, was individualized in each case. Estrogen and progesterone receptors were positive in all the gynecologic tumors but negative in the renal cell tumors.


CONCLUSIONS
This is apparently the largest report of synchronous renal cell carcinoma and gynecologic malignancies. Despite this rare condition, surgery should still be considered as primary treatment for these patients.
Wong
Cheung
C
Department of Obstetrics and Gynecology, University of Vermont/Fletcher Allen Health Care, Burlington 05401, USA. cheung.wong@vtmednet.org
Plante
Mark
M
Eltabbakh
Gamal
G
D002292:Carcinoma, Renal Cell / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005833:Genital Neoplasms, Female / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone