title: NTDB: Thermodynamic Database for Nucleic Acids, Version 2.0.
abstract: The second release of Thermodynamic Database for Nucleic Acids, NTDB 2.0, includes more than 4600 entries (250% increase over release 1.0). It contains sequence types and details of several thermodynamic parameters (enthalpy, DeltaH; entropy, DeltaS; Gibbs free energy, DeltaG; melting temperature, T(m)), experimental models and methods for extracting thermodynamic parameters, buffer conditions as well as all relevant literature information. In addition, the database statistics and references related to NTDB are included. Information on normal and modified nucleobases and nucleosides are collected in a new section 'Nucleoside' whereby data collected thus far will be release in NTDB 2.0. The NTDB is freely available at http://ntdb.chem.cuhk.edu.hk.
authors.affiliation: Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
authors.forename: Wing Lok Abe Kurtz
authors.initials: WL
authors.lastname: Chiu
authors.forename: Chun Ngai
authors.initials: CN
authors.lastname: Sze
authors.forename: Nap Tak
authors.initials: NT
authors.lastname: Ma
authors.forename: Lai Fan
authors.initials: LF
authors.lastname: Chiu
authors.forename: Chung Wai
authors.initials: CW
authors.lastname: Leung
authors.forename: Steve Chik Fun
authors.initials: SC
authors.lastname: Au-Yeung
mesh_terms: D030561:Databases, Nucleic Acid; D009696:Nucleic Acids / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D009696:Nucleic Acids