title: Intraoperative suspicion of gallbladder carcinoma in laparoscopic surgery: what to do?
abstract: The frequency of gallbladder cancer in Europe is less than 1% of all gallstone operations. With the introduction of laparoscopic surgery and the higher acceptance of this technique, patients with gallstones have gallbladder removal much earlier in their gallstone history. So the percentage of gallbladder carcinomas will decrease in the future. We report on our surgical procedures in patients with suspicious gallbladders having laparoscopic gallbladder removal, and how to proceed after the diagnosis of gallbladder carcinoma. From June 1990 to December 2001, we have performed 7,130 cholecystectomies in a single department. 47 of these patients (0.66%) were identified as having carcinoma. There were 40 females and 7 males, with a mean age of 70.6 years. In 17 cases (36%) there was a preoperative suspicion of malignancy. Most commonly, in 30 cases (64%), malignancy was suspected intraoperatively or diagnosed postoperatively after pathological examination of the resected gallbladder. We recommend removal with a bag for all gallbladders with a suspected wall or scleroatrophic calcified gallbladder area. In stage Tis or T1 laparoscopy + cholecystectomy is sufficient. For T2 and T3 we perform reoperation with liver bed resection and lymphadenectomy.
authors.affiliation: Chirurgische Klinik, DRK-Kliniken Westend Berlin, Germany. e.kraas@drk-kliniken.bln.de
authors.forename: E
authors.initials: E
authors.lastname: Kraas
authors.forename: D
authors.initials: D
authors.lastname: Frauenschuh
authors.forename: S
authors.initials: S
authors.lastname: Farke
mesh_terms: D017081:Cholecystectomy, Laparoscopic; D002764:Cholecystitis / Q000150:complications / Q000601:surgery; D002769:Cholelithiasis / Q000150:complications* / Q000601:surgery*; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012086:Reoperation