title: Clinical outcome and neurological sequelae in serologically confirmed cases of Japanese encephalitis patients in Assam, India.
abstract: We report the clinical outcome and prognostic factors in 39 cases of childhood Japanese Encephalitis admitted to a tertiary hospital of Upper Assam and followed up for 421 days in the community. The mortality rate was 20.5% in our study. The mean GCS (9.97 +/- 0.91) was higher in surviving cases than the fatal cases (GCS 7.5 +/- 1.78) at admission. The fatal cases died within 4.75 +/- 3.19 days in the hospital. All the patients had low BMI (surviving cases 13.54 +/- 2.3; fatal cases 12.05 +/- 0.12) and were anemic. Cerebrospinal fluid (CSF) was clear in 91.4% cases but pressure and protein content were increased in all cases. About 10% cases had parkinsonian features at the time of discharge. Residual symptoms remained in about one third of cases even after 421 days.
authors.affiliation: Regional Medical Research Centre, NE Region, ICMR, Dibrugarh, Assam, India.
authors.forename: H C
authors.initials: HC
authors.lastname: Baruah
authors.forename: D
authors.initials: D
authors.lastname: Biswas
authors.forename: D
authors.initials: D
authors.lastname: Patgiri
authors.forename: J
authors.initials: J
authors.lastname: Mahanta
mesh_terms: D002648:Child; D002675:Child, Preschool; D004672:Encephalitis, Japanese / Q000175:diagnosis / Q000401:mortality; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D011379:Prognosis