[Comparative study on graft of autogeneic iliac bone and tissue engineered bone].
OBJECTIVE
To compare the clinical results of repairing bone defect of limbs with tissue engineering technique and with autogeneic iliac bone graft.


METHODS
From July 1999 to September 2001, 52 cases of bone fracture were randomly divided into two groups (group A and B). Open reduction and internal fixation were performed in all cases as routine operation technique. Autogeneic iliac bone was implanted in group A, while tissue engineered bone was implanted in group B. Routine postoperative treatment in orthopedic surgery was taken. The operation time, bleeding volume, wound healing and drainage volume were compared. The bone union was observed by the X-ray 1, 2, 3, and 5 months after operation.


RESULTS
The sex, age and disease type had no obvious difference between groups A and B. all the wounds healed with first intention. The swelling degree of wound and drainage volume had no obvious difference. The operation time in group A was longer than that in group B (25 minutes on average) and bleeding volume in group A was larger than that in group B (150 ml on average). Bone union completed within 3 to 7 months in both groups. But there were 2 cases of delayed union in group A and 1 case in group B.


CONCLUSIONS
Repair of bone defect with tissue engineered bone has as good clinical results as that with autogeneic iliac bone graft. In aspect of operation time and bleeding volume, tissue engineered bone graft is superior to autogeneic iliac bone.
Shen
Bing
B
First Orthopedic Hospital of Chengdu, Chengdu Sichuan, P. R. China 610015.
Xie
Fu-lin
FL
Xie
Qing-fang
QF
D000293:Adolescent; D000328:Adult; D000368:Aged; D001132:Arm / Q000601:surgery; D018786:Bone Substitutes; D016025:Bone Transplantation / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D017102:Fracture Healing; D050723:Fractures, Bone / Q000601:surgery*; D006801:Humans; D007085:Ilium / Q000637:transplantation*; D007866:Leg / Q000601:surgery; D008297:Male; D008875:Middle Aged; D023822:Tissue Engineering; D014182:Transplantation, Autologous
D018786:Bone Substitutes