An extract of Tagetes lucida and its phenolic constituents as antioxidants.
Analysis of a methanolic extract of Tagetes lucida leaves has resulted in the isolation of a new flavonol glycoside, quercetagenin 3,4'-dimethyl ether 7-O-beta-D-glucopyranoside (1), two new phenolic acids, 3-(2-O-beta-D-glucopyranosyl-4-methoxyphenyl)propanoic acid (2) and its methylester (3), and known flavonols, aromatic acids, and 7-methoxycoumarin. Using the DPPH degrees test, the extract and some of its constituents showed a significant free-radical-scavenging effect in comparison to alpha-tocopherol and standard flavonols.
Aquino
Rita
R
Dipartimento di Scienze Farmaceutiche and Scuola di Specializzazione in Scienza e Tecnologia Cosmetiche, Università di Salerno, Invariante 11/C, 84084 Fisciano, Salerno, Italy. aquinorp@unisa.it
Cáceres
Armando
A
Morelli
Silvana
S
Rastrelli
Luca
L
D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds; D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006166:Guatemala; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D031686:Tagetes / Q000737:chemistry*; D024505:Tocopherols / Q000494:pharmacology
D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D006027:Glycosides; D010851:Picrates; C473162:quercetagenin 3,4'-dimethyl ether 7-O-glucopyranoside; C004931:1,1-diphenyl-2-picrylhydrazyl; D024505:Tocopherols