title: Inflammatory bowel disease in pregnancy.
abstract: Women and men with inflammatory bowel disease (IBD) frequently express concerns about fertility and pregnancy. The evidence suggests that women with IBD can expect to have a normal pregnancy outcome provided they have inactive disease. They have an increased risk of having a small or premature baby but the majority will have a normal outcome of pregnancy. The commonly used drugs appear to be safe and well tolerated in pregnancy. There remains a need for further studies in this area to help in the difficult decisions about the management of IBD around the time of conception and during pregnancy.
authors.affiliation: Bart's and the London School of Medicine, and Whipps Cross University Hospital, London, UK. e.m.almstead@mds.qmw.ac.uk
authors.forename: E M
authors.initials: EM
authors.lastname: Alstead
authors.forename: C
authors.initials: C
authors.lastname: Nelson-Piercy
mesh_terms: D000636:Aminosalicylic Acids / Q000009:adverse effects; D001379:Azathioprine / Q000009:adverse effects; D003093:Colitis, Ulcerative / Q000188:drug therapy; D003424:Crohn Disease / Q000188:drug therapy; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D007248:Infertility, Male / Q000139:chemically induced; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*; D008297:Male; D008727:Methotrexate / Q000009:adverse effects; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced / Q000209:etiology*; D011256:Pregnancy Outcome; D013256:Steroids / Q000009:adverse effects; D012460:Sulfasalazine / Q000009:adverse effects
chemical_list: D000636:Aminosalicylic Acids; D013256:Steroids; D012460:Sulfasalazine; D001379:Azathioprine; D008727:Methotrexate