title: Thrombin injection for failed stent graft repair of perforated atherosclerotic aortic ulcer.
abstract: We used direct thrombin injection to occlude a pseudoaneurysm that formed from a contained rupture of a penetrating atherosclerotic ulcer at the junction of the thoracic and abdominal aorta after we failed to seal the perforation with an endovascular stent graft. The principles of thrombin injection and the technical modifications specific for use in a false aneurysm of aortic origin are described. An evolving role for thrombin in endovascular therapy is suggested.
authors.affiliation: Vascular Center of Connecticut and the Department of Radiology and the Division of Vascular Surgery, St Francis Hospital and Medical Center, Hartford, CT 06105, USA. docrob8@aol.com
authors.forename: Robert S
authors.initials: RS
authors.lastname: Feld
authors.forename: Eugene
authors.initials: E
authors.lastname: Sullivan
authors.forename: Peter
authors.initials: P
authors.lastname: Morrison
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000628:therapy; D001018:Aortic Diseases / Q000628:therapy*; D001019:Aortic Rupture / Q000628:therapy*; D001161:Arteriosclerosis / Q000628:therapy*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D011475:Prosthesis Failure; D015607:Stents; D013917:Thrombin / Q000008:administration & dosage*; D014456:Ulcer / Q000628:therapy
chemical_list: D013917:Thrombin