title: Visual evoked potentials in successfully treated strabismic amblyopes and normal subjects.
abstract: OBJECTIVE
  To assess electrophysiological recovery in successfully treated strabismic amblyopes.
  
  
  METHODS
  Pattern reversal visual evoked potentials were recorded from 11 successfully treated strabismic amblyopes 7 to 11 years of age and 10 age-matched normal children using 12.5' and 50' checks.
  
  
  RESULTS
  Nine amblyopic eyes had recovered to a Snellen acuity of 6/6 or better, and the remaining 2 were 6/9 after patching. Comparison between the amblyopic and the fellow eyes showed significantly lower P100 amplitude for the amblyopic eyes with small checks (difference -16.7%; P <.02) and significantly longer latency with larger checks difference (+5.0%; P <.02). The P100 latencies to stimulation of both the amblyopic and fellow eyes by 12.5' checks were markedly longer than in normal subjects (amblyopic eye, +11.7%, P <.0001; fellow eye, +7.7% P <.002).
  
  
  CONCLUSIONS
  Successfully treated amblyopic eyes showed significantly longer latency than did normal eyes with small check stimulation. However, the nonamblyopic fellow eyes also showed significantly longer latency than did normal eyes, suggesting altered central processing.
authors.affiliation: Moorfields Eye Hospital, London, United Kingdom.
authors.forename: Patrick O
authors.initials: PO
authors.lastname: Watts
authors.forename: Magella M
authors.initials: MM
authors.lastname: Neveu
authors.forename: Graham E
authors.initials: GE
authors.lastname: Holder
authors.forename: John J
authors.initials: JJ
authors.lastname: Sloper
mesh_terms: D000550:Amblyopia / Q000503:physiopathology* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012683:Sensory Deprivation; D013285:Strabismus / Q000503:physiopathology* / Q000628:therapy; D016896:Treatment Outcome; D014792:Visual Acuity