Resistance and susceptibility of plants to fungal pathogens.
Plants are under continuous threat of infection by pathogens endowed with diverse strategies to colonize their host. Comprehensive biochemical and genetic approaches are now starting to reveal the complex signaling pathways that mediate plant disease resistance. Initiation of defense signaling often involves specific recognition of invading pathogens by the products of specialized host resistance (R) genes. Potential resistance signaling components have been identified by mutational analyses to be required for specific resistance in the model Arabidopsis and some crop species. Strikingly, many of the components share similarity to that of innate immune systems in animals. Evidence is also accumulating that plant pathogens have a number of ways to evade host defenses during the early stages of infection, similar to animal pathogens. These strategies are becoming much better understood in a number of plant-pathogen interactions. In this review, we focus on the current knowledge of host factors that control plant resistance and susceptibility to fungal pathogens. The knowledge accumulated in these studies will serve a fundamental basis for combating diseases in strategic molecular agriculture.
Toyoda
Kazuhiro
K
The Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK.
Collins
Nicholas C
NC
Takahashi
Akira
A
Shirasu
Ken
K
D005656:Fungal Proteins / Q000235:genetics / Q000502:physiology; D005658:Fungi / Q000737:chemistry / Q000502:physiology*; D007113:Immunity, Innate / Q000235:genetics / Q000276:immunology / Q000502:physiology; D010935:Plant Diseases / Q000209:etiology / Q000235:genetics / Q000382:microbiology*; D010940:Plant Proteins / Q000235:genetics / Q000276:immunology; D010944:Plants / Q000276:immunology*; D015398:Signal Transduction / Q000276:immunology; D037521:Virulence Factors
D005656:Fungal Proteins; D010940:Plant Proteins; D037521:Virulence Factors