Influences of naturally occurring and experimentally induced porcine pneumonia on blood parameters.
It had been the objective of the studies described to establish local and systemic changes by naturally occurring pneumonia or pneumonia experimentally induced by Pasteurella multocida and Haemophilus parasuis in swine. Acute and chronic pneumonia was found to alter the cytokine level of lung lavage fluid and affect the composition and function of blood cells, especially with regard to phagocytosis, radical formation and cell surface receptors. Interleukin-6 levels in blood plasma rose 24h after experimental intrabronchial infection. The influences of the changes on growth and meat quality are discussed.
Müller
G
G
Federal Institute for Health Protection of Consumers and Veterinary Medicine, Jena Branch, Naumburger Strasse 96a, D-07743, Jena, Germany.
Köhler
H
H
Diller
R
R
Rassbach
A
A
Berndt
A
A
Schimmel
D
D
D000208:Acute Disease; D000818:Animals; D001772:Blood Cell Count / Q000662:veterinary; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D002908:Chronic Disease; D005609:Free Radicals / Q000097:blood; D006190:Haemophilus / Q000502:physiology; D015850:Interleukin-6 / Q000097:blood; D008168:Lung / Q000473:pathology; D008460:Meat / Q000592:standards; D016979:Pasteurella multocida / Q000502:physiology; D010587:Phagocytosis; D011014:Pneumonia / Q000097:blood* / Q000382:microbiology / Q000662:veterinary*; D015375:Receptors, Interleukin-2 / Q000032:analysis; D013552:Swine; D013553:Swine Diseases / Q000097:blood* / Q000382:microbiology; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
D005609:Free Radicals; D015850:Interleukin-6; D015375:Receptors, Interleukin-2; D014409:Tumor Necrosis Factor-alpha