title: Transcatheter closure of patent ductus arteriosus in Chinese adults: immediate and long-term results.
abstract: BACKGROUND
  Transcatheter closure of patent ductus arteriosus (PDA) has been established as a safe and effective treatment for pediatric patients. However, long-term experience in adults remains limited. Therefore, our purpose is to report our experience with this approach in Chinese adults.
  
  
  METHODS
  Twenty-five patients (mean age, 34 years) who underwent transcatheter closure of PDA in a tertiary cardiology center in Hong Kong were recruited.
  
  
  RESULTS
  The mean PDA diameter measured by angiogram was 3.1 mm (range, 1.3 6.6 mm) and the mean pulmonary-to-systemic shunt was 1.65 (range, 1.3 1.8). All procedures were performed under local anesthesia. The average procedure and fluoroscopy times were 54   14 minutes and 14   4 minutes, respectively. The mean period of hospitalization was 4 days (range, 3 5 days). Immediate, one-month and late success rates were 96%, 92% and 84%, respectively.
  
  
  CONCLUSIONS
  Percutaneous closure of PDA in adults is a safe and feasible procedure. It should be a reasonable alternative for adult patients who are either not fit for open-chest surgery or who prefer a less invasive approach.
authors.affiliation: Department of Cardiology, Grantham Hospital, 125, Wong Chuk Hang Road, Hong Kong. Ronaldle@netvigator.com
authors.forename: Chi-Hang
authors.initials: CH
authors.lastname: Lee
authors.forename: Yim-Lung
authors.initials: YL
authors.lastname: Leung
authors.forename: Nim-Pong
authors.initials: NP
authors.lastname: Kwong
authors.forename: On-Hing
authors.initials: OH
authors.lastname: Kwok
authors.forename: Alex S B
authors.initials: AS
authors.lastname: Yip
authors.forename: Wing-Hing
authors.initials: WH
authors.lastname: Chow
mesh_terms: D000328:Adult; D000772:Anesthesia, Local; D006328:Cardiac Catheterization; D004374:Ductus Arteriosus, Patent / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D019736:Prostheses and Implants; D012189:Retrospective Studies; D012449:Safety; D013997:Time Factors