[Detection of TTV DNA and TTV IgG in 328 serum samples].
OBJECTIVE
To investigate the prevalence of TT virus(TTV) in a variety of populations in China.


METHODS
TTV DNA and anti TTV IgG were simultaneously tested by PCR and ELISA.


RESULTS
The positive rate of TTV DNA in the samples of 81 normal subjects, 92 blood donors, 123 hepatitis A-G patients and 32 hepatitis non A-G patients were 2.5%, 2.2%, 19.5% and 28.1%, respectively; and anti-TTV IgG was 1.2%, 3.7%, 26.8% and 34.4%, respectively. There were significant differences between the normal and the blood donor group and the hepatitis group; and among multi-infectious cases, the infection rate of TTV with HBV was as high as 75.0%.


CONCLUSIONS
The investigation indicated that TTV infection was very popular in different groups. Some of the normal and blood donor groups infected with TTV could become healthy carries of virus. And the hepatitis patients were the high risk group. In addition, TTV may be transmitted via other pathways besides blood.
Ma
D
D
First People's Hospital of Yancheng City, Jiangsu 224001, China.
Guo
N
N
Wang
H
H
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002681:China / Q000453:epidemiology; D004266:DNA Virus Infections / Q000453:epidemiology / Q000821:virology*; D004279:DNA, Viral / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006525:Hepatitis, Viral, Human / Q000821:virology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D015163:Superinfection / Q000821:virology; D022783:Torque teno virus / Q000235:genetics / Q000302:isolation & purification*
D000914:Antibodies, Viral; D004279:DNA, Viral; D007074:Immunoglobulin G