title: [Laminectomy for spinal cord compression occurring in hormone refractory prostate cancer].
abstract: In many cases of advanced prostate cancer, bone metastasis frequently occurs. Androgen deprivation therapy is very effective for these cases, but this therapy would result in failure, and symptomatic metastasis would develop. Approximately eighty percent of cases with bone metastasis showed epidural metastasis. When these lesions enlarge, spinal cord compression (SCC) occurs in five to ten percent of cases. Many urologist would choose an adequate modality for this problem, based on the prognosis and/or general status of each patient. In this article we overview laminectomy for SCC and present our experience.
authors.affiliation: Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Osamu
authors.initials: O
authors.lastname: Ogawa
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Arai
mesh_terms: D000368:Aged; D000726:Androgen Antagonists / Q000008:administration & dosage; D001859:Bone Neoplasms / Q000150:complications / Q000556:secondary*; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage; D006801:Humans; D007796:Laminectomy; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000473:pathology*; D011788:Quality of Life; D013117:Spinal Cord Compression / Q000209:etiology / Q000601:surgery*
chemical_list: D000726:Androgen Antagonists; D007987:Gonadotropin-Releasing Hormone