[Blood serum cholesterol and the state of the immune system].
This review deals with information on the relationship of the immunity system and the lipid transport system. The data of literature and the results obtained by the authors indicated that an elevated level of cholesterol in the blood serum is associated with the increased activity of the immunity system. On the one hand, lipids and their metabolites produce an immunomodulating effect and, on the other hand, biologically active molecules, synthesized by immunocompetent cells in the process of their activation and proliferation, regulate lipid metabolism.
Dotsenko
E A
EA
Republican Lipid Therapeutic and Diagnostic Center of Metabolic Therapy, State Medical University, Vitebsk, Belarus.
Iupatov
G I
GI
Novikov
D K
DK
Chirkin
A A
AA
D000818:Animals; D001693:Biological Transport, Active; D002784:Cholesterol / Q000097:blood*; D006801:Humans; D007107:Immune System; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D008055:Lipids; D002784:Cholesterol