Case of multiple myeloma mimicking an infectious disease with fever, intrahepatic cholestasis, renal failure, and pulmonary insufficiency.
We describe a case of multiple myeloma (MM) presenting with high fever, inflammatory chemistry abnormalities, simultaneous acute renal failure, cholestatic hepatitis, and acute lung failure. The extremely aggressive course and pulmonary involvement in the form of pulmonary alveolar proteinosis (PAP) are discussed, stressing the unusual nature of the findings and the variable picture of MM.
Vella
Francesco S
FS
Dipartimento di Clinica Medica, Immunologia e Malattie Infettive, University of Bari, Policlinico, Bari, Italy. diceglie@intmed.uniba.it
Simone
Barbara
B
Giannelli
Gianluigi
G
Pesolo
MariaTeresa
M
Ingravallo
Giuseppe
G
Gentile
Antonia
A
Antonaci
Salvatore
S
D058186:Acute Kidney Injury / Q000209:etiology*; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000747:Anemia, Hypochromic / Q000209:etiology; D001219:Aspartate Aminotransferases / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D002780:Cholestasis, Intrahepatic / Q000209:etiology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005334:Fever / Q000209:etiology*; D006801:Humans; D007239:Infections / Q000175:diagnosis; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D011649:Pulmonary Alveolar Proteinosis / Q000209:etiology*
D002097:C-Reactive Protein; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase