title: Prediction of outcome of physiotherapy in advanced Parkinson's disease.
abstract: OBJECTIVE
  Prediction of the effect of a home physiotherapy intervention on the basis of four clinical characteristics of patients with advanced Parkinson's disease.
  
  
  METHODS
  A repeated measures design comparing six weeks without treatment with six weeks of physiotherapy and a follow-up of 12 weeks.
  
  
  METHODS
  Persons with Parkinson's disease without dementia and suffering from considerable functional disability.
  
  
  METHODS
  Community physiotherapists treated patients in the home situation three times a week teaching cueing and conscious movement control for walking and carrying out transfers in and out of beds and chairs.
  
  
  METHODS
  Mental status, disease severity, age and mood were included as predictor variables. A new functional scale developed as part of a previous study was used as the dependent variable administered in both the hospital and the home to determine whether the outcome generalized from the learning to a different environment.
  
  
  RESULTS
  Only disease severity was a negative predictor of treatment outcome at home. In the hospital setting none of the factors predicted the immediate effect of treatment but cognitive ability and age were determinants of whether the treatment effects were maintained in the long term.
  
  
  CONCLUSIONS
  Using cueing and cognitive strategies benefited younger and older patients with Parkinson's disease alike. However, the findings indicate targeting of treatment at patients with milder disease severity and providing follow-up treatment for older and cognitively less able patients.
authors.affiliation: Department of Rehabilitation Sciences, Faculty of Physical Education and Physiotherapy, Katholieke Universiteit Leuven, Heverlee, Belgium. alice.nieuwboer@flok.kuleuven.ac.be
authors.forename: Alice
authors.initials: A
authors.lastname: Nieuwboer
authors.forename: Willy
authors.initials: W
authors.lastname: De Weerdt
authors.forename: René
authors.initials: R
authors.lastname: Dom
authors.forename: Kris
authors.initials: K
authors.lastname: Bogaerts
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D006233:Persons with Disabilities; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000534:rehabilitation*; D026741:Physical Therapy Modalities; D011379:Prognosis; D012720:Severity of Illness Index; D016896:Treatment Outcome