[Effect of motherwort herb on the myoelectric activity of uterus in rats].
OBJECTIVE
To investigate the effect of motherwort herb on the myoelectric activity of uterus in rats.


METHODS
A pair of bipolar Ag-AgCl electrode was implanted on the serosal surface of the uterus in rats, motherwort herb was injected intra-abdominal cavity in rats in dose of 0.1 ml, 0.2 ml and 0.4 ml respectively, and the changes of uterine myoelectric activity were observed.


RESULTS
Motherwort herb significantly increased the frequency and average amplitude of uterus slow waves of in rats. The frequency and maximum amplitude of single waves also obviously increased. The time course of outbreak waves was prolonged, the series intervals were reduced and the maximum amplitude in each outbreak was increased.


CONCLUSIONS
The exciting effect of motherwort herb on the uterine smooth muscle may have something to do with the alteration of the ion concentration in relation to myoelectric activity, resulting in the increase of myoelectric activity of pacesetter cells as well as in the acceleration of depolarization of spike activity.
Ma
Y M
YM
Lanzhou Medical College, Lanzhou 730000, Gansu, China.
Yang
D Y
DY
Tian
Z F
ZF
Qu
S Y
SY
Ding
Y H
YH
Wei
Y L
YL
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004576:Electromyography / Q000187:drug effects; D005260:Female; D031332:Leonurus / Q000737:chemistry; D009215:Myometrium / Q000187:drug effects / Q000502:physiology*; D018520:Plant Shoots; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats
D004365:Drugs, Chinese Herbal