title: Cephalometric analysis in patients with obstructive sleep apnea. Part I: diagnostic value.
abstract: BACKGROUND
  Morphological soft-tissue and skeletal anomalies of the upper extrathoracic airways are considered to be an etiological cofactor of nocturnal obstructive respiratory disorders.
  
  
  METHODS
  In this study 106 patients with a mean age of 56.1 +/- 8.4 years and a polysomnographic diagnosis of obstructive sleep apnea (OSA) were evaluated roentgenocephalometrically for soft-tissue and skeletal anomalies. Using cluster analysis and multivariate regression analysis, 18 skeletal variables, six pharyngeal variables and five hyoid variables were evaluated as predictor variables under the criterion variable "severity of the disorder". The body mass index (BMI), as a recognized risk factor of OSA, was taken separately into account.
  
  
  RESULTS
  No direct correlation was found between the skeletal cephalometric findings and severity of OSA. Only the position of the hyoid as an expression of a probably adaptive alteration to a changed head posture and tongue position was found to be a significant parameter correlating with the severity of OSA.
  
  
  CONCLUSIONS
  Whether cephalometric radiography is of direct diagnostic relevance in the diagnosis of OSA seems questionable in the light of the results of the present study.
authors.affiliation: Department of Orthodontics, Robert-Koch-Clinic, University of Freiburg i. Br., Germany. rose@zmk2.ukl.uni-freiburg.de
authors.forename: Edmund C
authors.initials: EC
authors.lastname: Rose
authors.forename: Richard
authors.initials: R
authors.lastname: Staats
authors.forename: Martin
authors.initials: M
authors.lastname: Lehner
authors.forename: Irmtrud E
authors.initials: IE
authors.lastname: Jonas
mesh_terms: D015992:Body Mass Index; D002508:Cephalometry / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D012044:Regression Analysis; D020181:Sleep Apnea, Obstructive / Q000145:classification / Q000175:diagnosis / Q000209:etiology*; D014059:Tongue
chemical_list: D010100:Oxygen