title: [Relationship between blood lead and free erythrocyte-protoporphyrin of female workers exposed to low concentration of lead operating environment].
abstract: The thesis focused in the research on whether low-lead operation would have effects on female workers. Based on investigation of 82 female workers under an operation environment with lead concentration of 0.0315 mg/m3, the following report indicated that differences did exist in terms of free erythrocyte-protoporphyrin(FEP), lead-blood(Pb-B) and lead-urine(Pb-U) values between the exposure and control groups. Pb-B, FEP and Pb-U were found closely interrelated and comparatively sensitive. Dose-response relationship was discovered in the process, positive percentage of Pb-B and FEP were 20.73% and 21.95% respectively, 13.4% above the maximal standard in both cases. In consequence, it was concluded that exposure to the 0.0315 mg/m3 lead concentration (0.03 mg/m3 being the normal) was still harmful to the female workers. Apart from that, the article suggested that the upper limit of lead in blood for common women (in Changchun city) was properly defined at 1.46 mumol/L. With FEP as the standard, the article made repective comparisons on the female workers' intelligence quotient (IQ) and the symptom occurrence of the neural system. People with IQ value between 60 to 79, 80 to 89, 90 to 109 or 110 to 119, the rates of showing positive report with FEP > or = 0.90 mumol/L were 27.6%, 22.6% and 15.0% respectively. The general occurrence rate on various level of FEP was obviously higher than that of the control group. The highest occurrence rate of 208.32% and 58.74% appeared when the FEP value was between 0.36 mumol/L to 0.54 mumol/L. When we made the comparison according to different symptoms as headache, dizziness, hypomnesis, somnipathy, palpitation and ephidrosis, the occurrence rate of headache was distinctively highger than that of the somnipathy.
authors.affiliation: School of Preventive Medicine of N. Bethune University of Medical Sciences, Changchun 130021, China.
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Liu
authors.forename: J
authors.initials: J
authors.lastname: Yang
mesh_terms: D000328:Adult; D004912:Erythrocytes / Q000737:chemistry*; D005260:Female; D006801:Humans; D007361:Intelligence Tests; D007854:Lead / Q000009:adverse effects* / Q000097:blood; D008875:Middle Aged; D016273:Occupational Exposure; D011524:Protoporphyrins / Q000097:blood*
chemical_list: D011524:Protoporphyrins; D007854:Lead