Malignant granular cell tumor of the lateral femoral cutaneous nerve: report of a case with cytogenetic analysis.
Malignant granular cell tumors (MGCTs) are rare neoplasms of uncertain histogenesis. We report a case of MGCT involving a peripheral nerve with peritoneal and omental dissemination in which cytogenetic findings are available. Our results show that MGCTs share some cytogenetic abnormalities with malignant peripheral nerve sheath tumors (MPNSTs), supporting the hypothesis that they may represent histogenetically related lesions.
Di Tommaso
Luca
L
Department of Oncology, Section of Anatomic Pathology, Marcello Malpighi, University of Bologna, Bologna, Italy.
Magrini
Elisabetta
E
Consales
Alessandro
A
Poppi
Massimo
M
Pasquinelli
Gianandrea
G
Dorji
Tsering
T
Benedetti
Giovanni
G
Baccarini
Paola
P
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002869:Chromosome Aberrations; D016586:Granular Cell Tumor / Q000235:genetics* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007621:Karyotyping; D008279:Magnetic Resonance Imaging; D008297:Male; D009362:Neoplasm Metastasis; D009852:Omentum / Q000473:pathology; D010524:Peripheral Nervous System Neoplasms / Q000235:genetics* / Q000473:pathology / Q000628:therapy*; D010537:Peritoneum / Q000473:pathology; D013514:Surgical Procedures, Operative