Clinical blood flow quantification with segmented k-space magnetic resonance phase velocity mapping.
OBJECTIVE
To evaluate the accuracy of segmented k-space magnetic resonance phase velocity mapping (PVM) in quantifying aortic blood flow from through-plane velocity measurements.


METHODS
Two segmented PVM schemes were evaluated, one with seven lines per segment (seg-7) and one with nine lines per segment (seg-9), in twenty patients with cardiovascular disease. A non-segmented (non-seg) PVM acquisition was also performed to provide the reference data.


RESULTS
There was agreement between the aortic flow curves acquired with segmented and non-segmented PVM. The calculated systolic and total flow volume per cycle from the seg-7 and the seg-9 scans correlated and agreed with the flow volumes from the non-seg scans (differences < 5%). Sign tests showed that there were no statistically significant differences (P-values > 0.05) between the segmented and the non-segmented PVM measurements [corrected]. Seg-9, which was the fastest among the three sequences, provided adequate spatial and temporal resolution (> 10 phases per cycle).


CONCLUSIONS
Segmented k-space PVM shows great clinical potential in blood flow quantification.
Chatzimavroudis
George P
GP
Section of Cardiovascular Imaging, Division of Radiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA. g.chatzimavroudis@csuohio.edu
Zhang
Haosen
H
Halliburton
Sandra S
SS
Moore
James R
JR
Simonetti
Orlando P
OP
Schvartzman
Paulo R
PR
Stillman
Arthur E
AE
White
Richard D
RD
D000368:Aged; D001011:Aorta / Q000473:pathology*; D001783:Blood Flow Velocity / Q000502:physiology; D001810:Blood Volume / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis