title: [Primary adenocarcinoma of the male urethra. A case report].
abstract: Primary adenocarcinoma of the male urethra is very uncommon, accounts for 5% of primary urethral cancers. All types of urethral carcinomas account for less than 1% of urinary malignancies in man. The prognosis remains poor despite the wide surgical treatment. The place of chemotherapy combined with radiotherapy must be defined by other studies. We report a case of primary locally advanced adenocarcinoma arising in the bulbo-membranous urethra. The patient was 29 years old, without any previous history of venerian disease. He was treated by combined external beam radiotherapy (total dose 67Gy) and chemotherapy (Cisplatinum). A marked reduction of tumor volume has been noted but the patient died because of the appearance of bone metastasis which failed to the systemic therapy.
authors.affiliation: Service de radiothérapie, institut national d'oncologie, BP 6213, Rabat, Maroc. h.bakkali@nancy.fnclcc.fr
authors.forename: H
authors.initials: H
authors.lastname: Bakkali
authors.forename: N
authors.initials: N
authors.lastname: Benjaafar
authors.forename: A
authors.initials: A
authors.lastname: Mansouri
authors.forename: H
authors.initials: H
authors.lastname: Errihani
authors.forename: F
authors.initials: F
authors.lastname: Kettani
authors.forename: A
authors.initials: A
authors.lastname: Benchekroun
authors.forename: B El Khalil
authors.initials: Bel K
authors.lastname: El Gueddari
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002945:Cisplatin / Q000627:therapeutic use*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D011379:Prognosis; D016896:Treatment Outcome; D014523:Urethral Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin