CNS angiitis in graft vs host disease.
Graft-vs-host disease (GVHD) is a potentially treatable cause of progressive neurologic decline after bone marrow transplantation (BMT). The authors present histologic confirmation of CNS granulomatous angiitis in a child with chronic GVHD after BMT. Since cranial MRI showed only nonspecific findings, CNS vasculitis associated with GVHD after BMT may be underdiagnosed.
Ma
M
M
Department of Neurology, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
Barnes
G
G
Pulliam
J
J
Jezek
D
D
Baumann
R J
RJ
Berger
J R
JR
D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D001921:Brain / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000601:surgery; D014657:Vasculitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
D000305:Adrenal Cortex Hormones