title: The EMBL Nucleotide Sequence Database: major new developments.
abstract: The EMBL Nucleotide Sequence Database (http://www.ebi.ac.uk/embl/) incorporates, organizes and distributes nucleotide sequences from all available public sources. The database is located and maintained at the European Bioinformatics Institute (EBI) near Cambridge, UK. In an international collaboration with DDBJ (Japan) and GenBank (USA), data are exchanged amongst the collaborating databases on a daily basis to achieve optimal synchronization. Webin is the preferred web-based submission system for individual submitters, while automatic procedures allow incorporation of sequence data from large-scale genome sequencing centres and from the European Patent Office (EPO). Database releases are produced quarterly. Network services allow free access to the most up-to-date data collection via FTP, Email and World Wide Web interfaces. EBI's Sequence Retrieval System (SRS) integrates and links the main nucleotide and protein databases plus many other specialized molecular biology databases. For sequence similarity searching, a variety of tools (e.g. Fasta, BLAST) are available which allow external users to compare their own sequences against the latest data in the EMBL Nucleotide Sequence Database and SWISS-PROT. All resources can be accessed via the EBI home page at http://www.ebi.ac.uk.
authors.affiliation: EMBL Outstation, The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. stoesser@ebi.ac.uk
authors.forename: Guenter
authors.initials: G
authors.lastname: Stoesser
authors.forename: Wendy
authors.initials: W
authors.lastname: Baker
authors.forename: Alexandra
authors.initials: A
authors.lastname: van den Broek
authors.forename: Maria
authors.initials: M
authors.lastname: Garcia-Pastor
authors.forename: Carola
authors.initials: C
authors.lastname: Kanz
authors.forename: Tamara
authors.initials: T
authors.lastname: Kulikova
authors.forename: Rasko
authors.initials: R
authors.lastname: Leinonen
authors.forename: Quan
authors.initials: Q
authors.lastname: Lin
authors.forename: Vincent
authors.initials: V
authors.lastname: Lombard
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Lopez
authors.forename: Renato
authors.initials: R
authors.lastname: Mancuso
authors.forename: Francesco
authors.initials: F
authors.lastname: Nardone
authors.forename: Peter
authors.initials: P
authors.lastname: Stoehr
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: Tuli
authors.forename: Katerina
authors.initials: K
authors.lastname: Tzouvara
authors.forename: Robert
authors.initials: R
authors.lastname: Vaughan
mesh_terms: D000818:Animals; D001483:Base Sequence; D003625:Data Collection; D030561:Databases, Nucleic Acid / Q000639:trends; D023281:Genomics; D016247:Information Storage and Retrieval; D020407:Internet; D017422:Sequence Analysis, DNA