[Progress in the study of obesity gene].
The study of obesity is one of the most active and fast moving area in the basic biomedical research. In the past three years, scientists had cloned the obese gene, clarified the structure of leptin, nailed down and cloned the gene of leptin receptor, partly revealed the mechanisms of leptin's effects which make the study of obesity entering the molecular age. It shows an attractive perspective for human being to control the body weight and increase the health level. The recent progress of all these aspects is discussed in this review.
Zhang
J F
JF
Department of Physiology, Beijing Medical University, Beijing 100083.
D000818:Animals; D001835:Body Weight; D005786:Gene Expression Regulation; D006801:Humans; D020738:Leptin / Q000235:genetics / Q000502:physiology*; D009478:Neuropeptide Y / Q000502:physiology; D009765:Obesity / Q000235:genetics*; D011956:Receptors, Cell Surface / Q000235:genetics / Q000502:physiology*; D054411:Receptors, Leptin
D020738:Leptin; D009478:Neuropeptide Y; D011956:Receptors, Cell Surface; D054411:Receptors, Leptin