WorfDB: the Caenorhabditis elegans ORFeome Database.
WorfDB (Worm ORFeome DataBase; http://worfdb.dfci.harvard.edu) was created to integrate and disseminate the data from the cloning of complete set of approximately 19 000 predicted protein-encoding Open Reading Frames (ORFs) of Caenorhabditis elegans (also referred to as the 'worm ORFeome'). WorfDB serves as a central data repository enabling the scientific community to search for availability and quality of cloned ORFs. So far, ORF sequence tags (OSTs) obtained for all individual clones have allowed exon structure corrections for approximately 3400 ORFs originally predicted by the C. elegans sequencing consortium. In addition, we now have OSTs for approximately 4300 predicted genes for which no ESTs were available. The database contains this OST information along with data pertinent to the cloning process. WorfDB could serve as a model database for other metazoan ORFeome cloning projects.
Vaglio
Philippe
P
Department of Cancer Biology, Dana-Farber Cancer Institute and Harvard Medical School, Smith 858, 1 Jimmy Fund Way, Boston, MA 02115, USA. philippe_vaglio@dfci.harvard.edu
Lamesch
Philippe
P
Reboul
Jérôme
J
Rual
Jean-François
JF
Martinez
Monica
M
Hill
David
D
Vidal
Marc
M
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D029742:Caenorhabditis elegans Proteins / Q000096:biosynthesis / Q000235:genetics*; D030561:Databases, Nucleic Acid; D016678:Genome; D016247:Information Storage and Retrieval; D016366:Open Reading Frames
D029742:Caenorhabditis elegans Proteins