title: Role of steroid receptors in the pathogenesis of tubal pregnancy.
abstract: OBJECTIVE
  To determine the role of steroid receptors in the pathogenesis of tubal pregnancy.
  
  
  METHODS
  Twenty-two women in the reproductive-age group who had undergone salpingectomy because of ectopic pregnancy or sterilization were enrolled. The study group consisted of 12 women who underwent salpingectomy for ectopic pregnancy. The control group included 10 patients in whom the tubes had been removed for elective sterilization.
  
  
  RESULTS
  Estrogen receptors were detected in 1 (8.3%) tube with ectopic pregnancy and in 10 (100%) normal tubes (P = .0001). Progesterone receptors were present in 4 (33.3%) tubes in the study group and in all the tubes in the control group (P = .002).
  
  
  CONCLUSIONS
  Our findings indicate that a basic cellular component, the steroid receptor, is damaged in tubes harboring pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, P.O. Box 5, Holon 58100, Israel. oscars@post.tau.ac.il
authors.forename: Oscar
authors.initials: O
authors.lastname: Sadan
authors.forename: Shimon
authors.initials: S
authors.lastname: Ginath
authors.forename: Sigi
authors.initials: S
authors.lastname: Rotmensch
authors.forename: Mona
authors.initials: M
authors.lastname: Boaz
authors.forename: Abraham
authors.initials: A
authors.lastname: Golan
authors.forename: Marek
authors.initials: M
authors.lastname: Glezerman
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000503:physiopathology*; D011960:Receptors, Estrogen / Q000032:analysis* / Q000502:physiology; D011980:Receptors, Progesterone / Q000032:analysis* / Q000502:physiology; D012307:Risk Factors
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone