[Osteoarticular allografts for repairing large bone or osteoarticular defects].
OBJECTIVE
To evaluate clinical outcome of bone or osteoarticular allografts.


METHODS
From September 1991 to November 1997, large bone or osteoarticular defects secondary to bone tumors resection in 36 patients and severe trauma in 2 patients were repaired by deep frozen or lyophilized allogeneic osteoarticular or diaphysis graft.


RESULTS
No obvious immune rejection to the grafts was observed in most of the patients in early stage after operation. The patients were followed up from 1 year and five months to 7 years and five months with an average of 4.2 years. Limb function was satisfactory in 74.19% of the 31 survival patients with large osteoarticular or diaphysis allografts.


CONCLUSIONS
Cryopreserved or lyophilized allogeneic osteoarticular grafts with decreased antigenicity and good biocompatibility are suitable materials for repairing large bone or osteoarticular defects.
Sun
L
L
Orthopaedic Center of PLA, 88th Hospital of PLA, Tai'an Shandong, P. R. China 271000. sunlei88@netease.com
Hu
Y Y
YY
Ning
Z J
ZJ
D000293:Adolescent; D000328:Adult; D019645:Arthroplasty, Replacement, Knee; D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation; D005260:Female; D005269:Femur / Q000637:transplantation; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018215:Osteoblastoma / Q000601:surgery*; D012189:Retrospective Studies