title: Effect of single and binary combinations of plant-derived molluscicides on different enzyme activities in the nervous tissue of Achatina fulica.
abstract: Effect of single and binary treatments of plant-derived molluscicides on different enzymes--acetylcholinesterase (AChE), lactic dehydrogenase (LDH) and acid/alkaline phosphatase (ACP/ALP)--in the nervous tissue of the harmful terrestrial snail Achatina fulica were studied. Sublethal in vivo 24-h exposure to 40% and 80% LC(50) of Azadirachta indica oil, Cedrus deodara oil, Allium sativum bulb powder, Nerium indicum bark powder and binary combinations of A. sativum (AS) + C. deodara (CD) and CD + A. indica (AI) oils significantly altered the activity of these enzymes in the nervous tissue of Achatina fulica. The binary treatment of AS + CD was more effective against AChE, LDH, and ALP than the single ones. However, binary treatment of AI + CD was more effective against ALP.
authors.affiliation: Department of Zoology, DDU Gorakhpur University, Gorakhpur, India.
authors.forename: I G
authors.initials: IG
authors.lastname: Rao
authors.forename: Amrita
authors.initials: A
authors.lastname: Singh
authors.forename: V K
authors.initials: VK
authors.lastname: Singh
authors.forename: D K
authors.initials: DK
authors.lastname: Singh
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000135:Acid Phosphatase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004798:Enzymes / Q000378:metabolism*; D017952:Ganglia, Invertebrate / Q000187:drug effects* / Q000201:enzymology; D066298:In Vitro Techniques; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008975:Molluscacides / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D012908:Snails / Q000201:enzymology*
chemical_list: D004338:Drug Combinations; D004791:Enzyme Inhibitors; D004798:Enzymes; D008975:Molluscacides; D010936:Plant Extracts; D007770:L-Lactate Dehydrogenase; D000110:Acetylcholinesterase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase