title: Pharmacology of Na+/Ca2+ exchanger.
abstract: KB-R7943 inhibits the Na(+)/Ca(2+) exchanger in an independent manner or in a manner dependent on the direction of the current. This effect may be due to the experimental protocols bawed on the competition between the drug and external substrate ions. Some antiarrhythmic drugs inhibit NCX. A new column of NCX was added in Sicilian Gambit.
authors.affiliation: Department of Pharmacology, School of Medicine, Fukushima Medical University, Fukushima, Japan. jkimura@fmu.ac.jp
authors.forename: Junko
authors.initials: J
authors.lastname: Kimura
authors.forename: Yasuhide
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Libing
authors.initials: L
authors.lastname: Li
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Watano
mesh_terms: D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D002118:Calcium / Q000502:physiology; D008954:Models, Biological; D008955:Models, Cardiovascular; D019831:Sodium-Calcium Exchanger / Q000037:antagonists & inhibitors* / Q000502:physiology*; D013329:Structure-Activity Relationship; D013890:Thiourea / Q000031:analogs & derivatives* / Q000494:pharmacology*
chemical_list: C101670:2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate; D000889:Anti-Arrhythmia Agents; D019831:Sodium-Calcium Exchanger; D013890:Thiourea; D002118:Calcium