Effect of Maksar on antioxidant system in rats with type IIa alimentary hyperlipoproteinemia.
The development of type IIa alimentary hyperlipoproteinemia in rats was accompanied by changes in activity of glutathione-dependent enzymes, exhaustion of the reserves of antioxidant vitamins in the liver and blood, and intensification of lipid peroxidation. The hepatoprotective preparation Maksar obtained from far-eastern plants Maachia amurensis and containing natural biological antioxidants normalized blood lipid composition, corrected liver lipidosis, and improved the antioxidant defense system.
Yan'kova
V I
VI
Vladivostok Branch, Far-Eastern Research Center for Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Sciences, Institute of Medical Climatology and Rehabilitative Therapy, Vladivostok.
Gvozdenko
T A
TA
Ivanova
I L
IL
Fedoreev
S A
SA
Kulesh
N I
NI
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004195:Disease Models, Animal; D005419:Flavonoids; D005978:Glutathione / Q000378:metabolism; D006938:Hyperlipoproteinemia Type II / Q000378:metabolism* / Q000628:therapy*; D015227:Lipid Peroxidation; D008055:Lipids / Q000097:blood; D008099:Liver / Q000378:metabolism; D008297:Male; D010636:Phenols / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D011108:Polymers / Q000494:pharmacology*; D059808:Polyphenols; D051381:Rats; D017208:Rats, Wistar
D000975:Antioxidants; D005419:Flavonoids; D008055:Lipids; D010636:Phenols; D010936:Plant Extracts; D011108:Polymers; D059808:Polyphenols; C476800:maksar; D005978:Glutathione