title: Heart transplantation in Portugal: current status and future perspectives.
abstract: No other form of therapy, whether medical or surgical, has an impact comparable to heart transplantation on the quality of life and survival of selected patients with severe heart failure. In the EU and in the USA about 10 patients per million of population are transplanted each year. In Portugal, a country with a population of 10 million, 100 patients should be transplanted each year, but only 12 patients were in fact transplanted in 1999. We rank 17th, in terms of the rate of heart transplantation per million of population, among the 23 European countries with registries of this activity. This is due to structural and organizational deficiencies of three main types: the lack of professional teams dedicated to severe heart failure treatment and heart transplantation; the lack of infrastructure, particularly heart failure wards and heart failure outpatient clinics; and the inappropriate distribution of the tasks associated with heart transplantation and patient follow-up. We present an estimate of the number of potential heart transplant candidates in Portugal, based on the EPICA study and a prediction of the resources needed for a successful heart transplantation program serving a population of 2 million. This was based on what is known of the natural history, morbidity and mortality of severe heart failure, on our own experience in this field, and finally on the experience of a large international heart transplantation center. The recommendations of the British Transplantation Society and those of the Department of Cardiothoracic Surgery of Stanford University were also taken into account.
authors.affiliation: Serviço de Cardiologia, Hospital de S. João, Porto.
authors.forename: J Silva
authors.initials: JS
authors.lastname: Cardoso
authors.forename: Cândida
authors.initials: C
authors.lastname: Fonseca
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Rebocho
authors.forename: R Palma
authors.initials: RP
authors.lastname: Reis
authors.forename: A Norton
authors.initials: AN
authors.lastname: de Matos
authors.forename: J Martins
authors.initials: JM
authors.lastname: Correia
mesh_terms: D005544:Forecasting; D006333:Heart Failure / Q000601:surgery*; D016027:Heart Transplantation / Q000706:statistics & numerical data* / Q000639:trends*; D006801:Humans; D018579:Patient Selection; D011174:Portugal; D012720:Severity of Illness Index; D009927:Tissue and Organ Procurement