title: WorfDB: the Caenorhabditis elegans ORFeome Database.
abstract: WorfDB (Worm ORFeome DataBase; http://worfdb.dfci.harvard.edu) was created to integrate and disseminate the data from the cloning of complete set of approximately 19 000 predicted protein-encoding Open Reading Frames (ORFs) of Caenorhabditis elegans (also referred to as the 'worm ORFeome'). WorfDB serves as a central data repository enabling the scientific community to search for availability and quality of cloned ORFs. So far, ORF sequence tags (OSTs) obtained for all individual clones have allowed exon structure corrections for approximately 3400 ORFs originally predicted by the C. elegans sequencing consortium. In addition, we now have OSTs for approximately 4300 predicted genes for which no ESTs were available. The database contains this OST information along with data pertinent to the cloning process. WorfDB could serve as a model database for other metazoan ORFeome cloning projects.
authors.affiliation: Department of Cancer Biology, Dana-Farber Cancer Institute and Harvard Medical School, Smith 858, 1 Jimmy Fund Way, Boston, MA 02115, USA. philippe_vaglio@dfci.harvard.edu
authors.forename: Philippe
authors.initials: P
authors.lastname: Vaglio
authors.forename: Philippe
authors.initials: P
authors.lastname: Lamesch
authors.forename: Jérôme
authors.initials: J
authors.lastname: Reboul
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Rual
authors.forename: Monica
authors.initials: M
authors.lastname: Martinez
authors.forename: David
authors.initials: D
authors.lastname: Hill
authors.forename: Marc
authors.initials: M
authors.lastname: Vidal
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D029742:Caenorhabditis elegans Proteins / Q000096:biosynthesis / Q000235:genetics*; D030561:Databases, Nucleic Acid; D016678:Genome; D016247:Information Storage and Retrieval; D016366:Open Reading Frames
chemical_list: D029742:Caenorhabditis elegans Proteins