title: [Clinical manifestations of neuroendocrine tumors].
abstract: A complex clinico-functional morphologic examination was carried out on 125 patients with neuroendocrine tumors (NET): carcinoids, pheochromocytoma and multiple endocrine adenomatosis (an integral part of which is pheochromocytoma, gastrinoma and medullar C-cell carcinoma of thyroid gland). There was a clinical examination using laboratory and instrumental methods in pre- and postoperative periods, morphological research of removed tumors. According to the obtained indications, selective angiography and static scintigraphy with 111Tc was carried out. Isotopes 111-In were used in 3 patients for scintigraphic research of somatostatinpositive NET. The following versions were selected: serotonin and sympathoadrenal clinical variants of monoaminoforming NET, clinical versions of multiple endocrine neoplasias, a clinical version of adenocarcinomas having in their composition cells with neuroendocrine differentiation accompanied by neuroendocrine paraneoplastic syndrome. There were offered a term and definitions of hyperproduction syndrome of regulatory peptides in case of NET.
authors.forename: P A
authors.initials: PA
authors.lastname: Dulin
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000473:pathology; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology; D002395:Catecholamines / Q000378:metabolism*; D004415:Dyspepsia / Q000209:etiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000150:complications / Q000175:diagnosis / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism*; D013610:Tachycardia / Q000209:etiology*; D013964:Thyroid Neoplasms / Q000150:complications / Q000175:diagnosis / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D002395:Catecholamines; D012701:Serotonin