title: [Experimental study on the biocompatibility and toxicology of interface between hydroxyapatite coating and bone].
abstract: According to "The standards for biological evaluation of bio-materials and bio-products abbreviated to STANDARDS" newly set by the Ministry of Health, PRC, 5 observation indexes were selected to evaluate systematically the biocompatibility and toxicology of China-made hydroxyapatite, which is clinicall used. The results revealed no effects of allergy, mutation and hemoclasis reaction except mild cytotoxicity. These indicate that the China-made hydroxyapatite meets the demand of STANDADS and thus may be clinically with safety.
authors.affiliation: Department of Plastic and Orthopaedics, 452th Hospital PLA, Chengdu 610061.
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
authors.forename: H
authors.initials: H
authors.lastname: Zou
mesh_terms: D020099:Coated Materials, Biocompatible / Q000633:toxicity*; D006882:Hydroxyapatites / Q000633:toxicity*; D008422:Materials Testing
chemical_list: D020099:Coated Materials, Biocompatible; D006882:Hydroxyapatites