A chemical adaptor system designed to link a tumor-targeting device with a prodrug and an enzymatic trigger.
Gopin
Anna
A
Department of Organic Chemistry, School of chemistry, Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Pessah
Neta
N
Shamis
Marina
M
Rader
Christoph
C
Shabat
Doron
D
D000588:Amines / Q000737:chemistry / Q000378:metabolism; D017151:Antibodies, Catalytic / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D001711:Biotransformation; D004337:Drug Carriers / Q000008:administration & dosage / Q000737:chemistry* / Q000493:pharmacokinetics; D016503:Drug Delivery Systems / Q000379:methods*; D015195:Drug Design; D008333:Mandelic Acids / Q000737:chemistry*; D011355:Prodrugs / Q000493:pharmacokinetics*
D000588:Amines; D017151:Antibodies, Catalytic; D000970:Antineoplastic Agents; D004337:Drug Carriers; D008333:Mandelic Acids; D011355:Prodrugs; C014600:4-hydroxymandelic acid