Complementary DNA sequence of the HLA-B*3924 allele.
We have isolated the complete coding region of HLA-B*39 from a Spanish Caucasoid, using a new PCR primer for its 5' untranslated region. The cDNA matched partial genomic sequences of B*3924, an allele whose distribution appears to be restricted to Mediterranean and Arabian Caucasoids. A single amino acid change exclusive to B*3924 (threonine-98) distinguishes it from B*3903.
Estefanía
E
E
Servicio de Immunología, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Gómez-Lozano
N
N
de Pablo
R
R
Moreno
M E
ME
Vilches
C
C
D020121:5' Untranslated Regions; D000483:Alleles; D019943:Amino Acid Substitution; D001483:Base Sequence; D017124:Conserved Sequence; D018076:DNA, Complementary / Q000235:genetics*; D015235:HLA-B Antigens / Q000235:genetics*; D059946:HLA-B39 Antigen; D006801:Humans; D019083:Mediterranean Region; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D013030:Spain; D044465:White People / Q000235:genetics
D020121:5' Untranslated Regions; D018076:DNA, Complementary; D015235:HLA-B Antigens; C471435:HLA-B*39:24 antigen; D059946:HLA-B39 Antigen