[Treatment of hemangioma in oral and maxillofacial region with pingyangmycin injection].
OBJECTIVE
To investigate the indication and result in hemangioma in oral and maxillofacial region with Pingyangmycin injection.


METHODS
1282 patients (554 males and 728 females) with hemangioma in oral and maxillofacial region have been treated in our hospital during the 10-year period from May 1990 to March 1999. The patients range between 0.5-84 years old. Lip, cheek and tongue were usually involved. 1211 patients were treated with injection of Pingyangmycin(about 0.89 mg/ml) and dexamethasone (about 0.55 mg/ml), 1 time/1-2 weeks.


RESULTS
The curative rates of cavernous hemangioma and strawberry hemangioma were 93.87% and 84.90%, but that of plexiform hemangioma was 22.22% and those of portwine stain and central hemangioma of the jaws were 0%, respectively. Serious complications associated with Pingyangmycin injection, such as pulmonary fibrosis were not seen.


CONCLUSIONS
Injection of Pingyangmycin is selective primary method for cavernous and strawberry hemangioma treatment.
Wang
C
C
Department of Oral and Maxillofacial Surgery, College of Stomatology, West China University of Medical Sciences.
Gao
Q
Q
Fu
F
F
Wen
Y
Y
Dai
X
X
Gong
H
H
Lu
X
X
D000293:Adolescent; D000328:Adult; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage* / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage* / Q000031:analogs & derivatives*; D002648:Child; D002675:Child, Preschool; D005153:Facial Neoplasms / Q000188:drug therapy*; D005260:Female; D006392:Hemangioma, Cavernous / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015552:Injections, Intralesional; D007573:Jaw Neoplasms / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000188:drug therapy*
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin; C021771:zhengguangmycin