Efficacy of oral minocycline and hyperthermic treatment in a case of atypical mycobacterial skin infection by Mycobacterium marinum.
We report a case of atypical mycobacterial dermal infection caused by M. marinum, which was effectively treated with oral administration of minocycline and local hyperthermic treatment using chemical pocket warmers. A daily oral dose of 200 mg of minocycline was given, and local hyperthermic treatment was applied every evening for 5-6 hours with a disposable chemical pocket warmer. After 2.5 months of therapy, the lesion healed completely with scar formation. At 24 months after the completion of treatments, there is no sign of recurrence.
Hisamichi
Katsuya
K
Department of Dermatology, Juntendo University School of Medicine, Hongo, Tokyo, Japan.
Hiruma
Masataro
M
Yamazaki
Masashi
M
Matsushita
Akiko
A
Ogawa
Hideoki
H
D000284:Administration, Oral; D000328:Adult; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005500:Follow-Up Studies; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D008911:Minocycline / Q000008:administration & dosage*; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000628:therapy*; D009170:Nontuberculous Mycobacteria / Q000302:isolation & purification*; D017192:Skin Diseases, Bacterial / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome
D008911:Minocycline