title: New dimeric naphthopyrones from Aspergillus niger.
abstract: Three new dimeric naphthopyrones, asperpyrones A (1), B (2), and C (3), together with two known compounds, fonsecinone A (4) and aurasperone A (5), have been isolated from okara that was fermented with Aspergillus niger JV-33-48. Compounds 1, 4, and 5 showed inhibitory activity on Taq DNA polymerase.
authors.affiliation: Natural Products Chemistry, Division of Applied Biological Chemistry, Graduate School of Agriculture and Biological Sciences, Osaka Prefecture University, 1-1 Gakuencho, Sakai, Osaka 599-8531, Japan.
authors.forename: Kohki
authors.initials: K
authors.lastname: Akiyama
authors.forename: Seigo
authors.initials: S
authors.lastname: Teraguchi
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Hamasaki
authors.forename: Mika
authors.initials: M
authors.lastname: Mori
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Tatsumi
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohnishi
authors.forename: Hideo
authors.initials: H
authors.lastname: Hayashi
mesh_terms: D001234:Aspergillus niger / Q000737:chemistry*; D001483:Base Sequence; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007564:Japan; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019906:Nuclear Magnetic Resonance, Biomolecular; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019914:Taq Polymerase / Q000037:antagonists & inhibitors*
chemical_list: D004791:Enzyme Inhibitors; D009281:Naphthalenes; D011753:Pyrones; D019914:Taq Polymerase