[Phospholipase activities of Candida albicans isolates from oral pre-malignant lesions and oral cancers].
OBJECTIVE
The aim of this study is to compare activities of phospholipase of Candida albicans isolates from oral cavities of two groups of patients, including oral pre-malignant lesions and oral cancers.


METHODS
A total of 55 isolates, including oral pre-malignant lesions (21), oral cancers (15), and normal health control (19), were studied using the precipitate zone assay on the egg yolk agar.


RESULTS
No significant difference was found in phospholipase activities between these isolates from normal controls and oral pre-malignant lesions, while the activities of phospholipase of isolates from oral cancers were higher than those of the normal controls.


CONCLUSIONS
Candida albicans may play different roles in different manners in these two closely related diseases.
Zhou
M
M
College of Stomatology, West China University of Medical Sciences.
Zeng
X
X
Chen
Q
Q
Zhao
M
M
Lin
M
M
Wang
X
X
Zhang
G
G
Li
B
B
D002176:Candida albicans / Q000201:enzymology* / Q000472:pathogenicity; D002294:Carcinoma, Squamous Cell / Q000382:microbiology*; D006801:Humans; D009062:Mouth Neoplasms / Q000382:microbiology*; D010740:Phospholipases / Q000378:metabolism*; D011230:Precancerous Conditions / Q000382:microbiology*; D014774:Virulence
D010740:Phospholipases