title: [Evaluation of arrhythmic risk in coronary insufficiency].
abstract: Half of all deaths occurring in patients with heart failure are sudden deaths probably related to a malignant ventricular arrhythmia. The pathophysiological mechanisms of these arrhythmias are unclear, but left ventricular function, hypokalaemia accentuated by diuretics and treatments altering inotropism play a definite role. Because of the diversity of aetiologies generating heart failure, the multiplicity of fatal arrhythmias and the multifactorial origin of these arrhythmias, there is no formal marker for the risk of sudden death in patients with heart failure, at the present time. In addition to the NYHA classification and detection of episodes of syncope, assessment of these patients must be as complete as possible, at least including repeated evaluation of the ejection fraction, Holter ECG monitoring and detection of delayed ventricular potentials.
authors.affiliation: Service de Cardiologie, CHU de Rangueil, 1, avenue Jean-Poulhès, 31403 Toulouse.
authors.forename: S
authors.initials: S
authors.lastname: Boveda
authors.forename: M
authors.initials: M
authors.lastname: Galinier
authors.forename: P
authors.initials: P
authors.lastname: Lagrange
authors.forename: M
authors.initials: M
authors.lastname: Delay
authors.forename: P
authors.initials: P
authors.lastname: Massabuau
authors.forename: B
authors.initials: B
authors.lastname: Dongay
authors.forename: N
authors.initials: N
authors.lastname: Prouteau
authors.forename: J
authors.initials: J
authors.lastname: Marti
authors.forename: J M
authors.initials: JM
authors.lastname: Fauvel
authors.forename: J P
authors.initials: JP
authors.lastname: Bounhoure
mesh_terms: D001145:Arrhythmias, Cardiac / Q000209:etiology*; D015415:Biomarkers; D003327:Coronary Disease / Q000145:classification / Q000150:complications* / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D016757:Death, Sudden, Cardiac / Q000209:etiology; D004232:Diuretics / Q000009:adverse effects; D015716:Electrocardiography, Ambulatory; D022062:Electrophysiologic Techniques, Cardiac; D006333:Heart Failure / Q000145:classification / Q000150:complications* / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced / Q000150:complications; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D013318:Stroke Volume; D013575:Syncope / Q000175:diagnosis / Q000209:etiology; D019462:Syncope, Vasovagal; D016277:Ventricular Function, Left
chemical_list: D015415:Biomarkers; D004232:Diuretics