Species prevalence and antibacterial resistance of enterococci isolated in Kuwait hospitals.
This study investigated the species prevalence and antibacterial resistance among enterococci isolated in Kuwait hospitals. They consisted of 415 isolates of Enterococcus faecalis (85.3 %), Enterococcus faecium (7.7 %), Enterococcus casseliflavus (4.0 %), Enterococcus avium (1.2 %), Enterococcus durans (1.0 %), Enterococcus gallinarium (0.5 %) and Enterococcus bovis (0.2 %) isolated from urine (36.6 %), blood (10.4 %), wound swabs (11.0 %), stool samples (12.0 %), high vaginal swabs (9.0 %), endocervical swabs (3.0 %) and miscellaneous sources (18.0 %). All of them were susceptible to linezolid. Fifty-two (12.5 %) isolates were ampicillin resistant but none of them produced beta-lactamase. They were resistant to erythromycin (63.3 %), tetracycline (60.5 %), ciprofloxacin (40.0 %), chloramphenicol (28.0 %), vancomycin (2.6 %), and teicoplanin (2.6 %). Fourteen, 19 and 20 % of them expressed high-level resistance to gentamicin, kanamycin and streptomycin, respectively. All of the vancomycin-resistant strains carried the vanA phenotype and genotype. There was no evidence of clonal spread of the vancomycin-resistant isolates.
Udo
Edet E
EE
Department of Microbiology, Faculty of Medicine1 and Department of Pharmaceutical Chemistry, Faculty of Pharmacy2, Kuwait University, PO Box 24923, Safat 13110, Kuwait.
Al-Sweih
Noura
N
Department of Microbiology, Faculty of Medicine1 and Department of Pharmaceutical Chemistry, Faculty of Pharmacy2, Kuwait University, PO Box 24923, Safat 13110, Kuwait.
Phillips
Oludotun A
OA
Department of Microbiology, Faculty of Medicine1 and Department of Pharmaceutical Chemistry, Faculty of Pharmacy2, Kuwait University, PO Box 24923, Safat 13110, Kuwait.
Chugh
Tulsi D
TD
Department of Microbiology, Faculty of Medicine1 and Department of Pharmaceutical Chemistry, Faculty of Pharmacy2, Kuwait University, PO Box 24923, Safat 13110, Kuwait.
D000081:Acetamides / Q000494:pharmacology; D000668:Ampicillin Resistance / Q000235:genetics; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003428:Cross Infection; D024881:Drug Resistance, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D013293:Enterococcus faecalis / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D016984:Enterococcus faecium / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D005838:Genotype; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology / Q000382:microbiology*; D006761:Hospitals; D006801:Humans; D007730:Kuwait / Q000453:epidemiology; D000069349:Linezolid; D008826:Microbial Sensitivity Tests; D023303:Oxazolidinones / Q000494:pharmacology; D016133:Polymerase Chain Reaction; D015995:Prevalence; D020713:Vancomycin Resistance / Q000235:genetics; D018440:beta-Lactam Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000378:metabolism
D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D001618:beta-Lactamases; D000069349:Linezolid