title: Primary small-cell carcinoma of the endometrium: clinicopathological study of a case and review of the literature.
abstract: BACKGROUND
  Small-cell carcinomas are almost always primary in the lungs and are highly malignant. These tumors may also occur in the female genital tract. However, primary small-cell carcinoma of the endometrium is extremely rare with very few cases reported in the English literature. This tumor may exhibit evidence of neuroendocrine differentiation and has a high propensity for systemic spread and poor prognosis.
  
  
  METHODS
  A 55-year-old postmenopausal woman with primary small-cell carcinoma of the endometrium, FIGO stage Ib, underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and sampling node biopsies of the parametrial spaces, followed by adjuvant combined chemotherapy.
  
  
  CONCLUSIONS
  A case of small-cell carcinoma of the endometrium, is reported and its clinical, histological and immunohistochemical features are discussed.
authors.affiliation: Department of Obstetrics and Gynaecology, G. Chatzikosta-General State Hospital, Ioannina, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Varras
authors.forename: Ch
authors.initials: Ch
authors.lastname: Akrivis
authors.forename: A
authors.initials: A
authors.lastname: Demou
authors.forename: G
authors.initials: G
authors.lastname: Hadjopoulos
authors.forename: S
authors.initials: S
authors.lastname: Stefanaki
authors.forename: N
authors.initials: N
authors.lastname: Antoniou
mesh_terms: D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009367:Neoplasm Staging; D014463:Ultrasonography