Sporadic Burkitt's lymphoma of the head and neck in the pediatric population.
Burkitt's lymphoma (BL) is one of the fastest growing malignancies in the pediatric population in the United States. BL is a high-grade B-cell Non-Hodgkin's lymphoma (NHL) which exists in endemic, sporadic, and human immunodeficiency-associated subtypes. The African, or endemic, variant usually involves the maxilla and other facial bones while head and neck manifestations in non-endemic BL are rare. We present three unusual present ations of sporadic BL stemming from Waldeyer's ring and the orbit. The clinical and pathologic features of BL are reviewed.
Banthia
Vishal
V
Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian, University Hospital of Columbia, New York, NY, USA.
Jen
Albert
A
Kacker
Ashutosh
A
D000293:Adolescent; D002051:Burkitt Lymphoma / Q000175:diagnosis* / Q000453:epidemiology* / Q000235:genetics; D002648:Child; D002898:Chromosomes, Human, Pair 8 / Q000235:genetics; D005260:Female; D015870:Gene Expression / Q000235:genetics; D016259:Genes, myc / Q000235:genetics; D016158:Genes, p53 / Q000235:genetics; D004854:Herpesvirus 4, Human / Q000235:genetics; D006801:Humans; D015994:Incidence; D008279:Magnetic Resonance Imaging; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging* / Q000473:pathology*; D014066:Palatine Tonsil / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic