[Ultrastructural and Ca/P changes of the regenerated bone after mandibular distraction in goats].
OBJECTIVE
The aim of this study was to examine the ultra structural and the changes of Ca/P elements of the new bone resulting from mandibular distraction osteogenesis.


METHODS
Bilateral mandibular osteotomies were performed in six goats. The mandibles in all animals were lengthened 10 mm using a custom made distracter. Each 2 goats were sacrificed respectively at 2, 4 and 8 weeks after completion of distraction. The distracted callus were harvested and processed for SEM evaluation and Ca/P ratio analysis.


RESULTS
The newly generated bone in distraction gap was confirmed by SEM examination, and the contents of Ca, P were found to be elevated with the maturity of distracted callus.


CONCLUSIONS
This study suggested that newly formed bone by mandibular distraction osteogenesis in goats could be remodeled to normal bone.
Hu
J
J
College of Stomatology, West China University of Medical Sciences.
Li
J
J
Wang
D
D
Liao
Y
Y
D000818:Animals; D001861:Bone Regeneration; D002118:Calcium / Q000032:analysis*; D006041:Goats; D008334:Mandible / Q000737:chemistry / Q000648:ultrastructure*; D019857:Osteogenesis, Distraction; D010758:Phosphorus / Q000032:analysis*
D010758:Phosphorus; D002118:Calcium