Dual tail catheters for infusion and sampling in rats as an efficient platform for metabolic experiments.
The authors present a technique for establishing a virtually stress-free dual-catheter system in rats, allowing researchers to conduct extended, complex experimental procedures involving the simultaneous infusion of multiple compounds and frequent collection of blood samples.
Guo
ZengKui
Z
Endocrine Research Unit, Mayo Foundation, Rochester, MN 55905, USA. guo.zengkui@mayo.edu
Zhou
Lianzhen
L
D000818:Animals; D001158:Arteries; D001800:Blood Specimen Collection / Q000379:methods / Q000662:veterinary*; D002404:Catheterization / Q000379:methods / Q000662:veterinary*; D007262:Infusions, Intravenous / Q000379:methods / Q000662:veterinary*; D051381:Rats; D012376:Rodent Diseases / Q000517:prevention & control; D013312:Stress, Physiological / Q000517:prevention & control / Q000662:veterinary; D013623:Tail / Q000098:blood supply*; D014680:Veins