title: Antigen-driven clonal T cell expansion in disorders of hematopoiesis.
abstract: Patients with myelodysplastic syndrome, aplastic anemia, and LGL leukemia may have overlapping clinical features. This commentary highlights a possible common pathogenetic mechanism of antigen-driven cytotoxic T lymphocytes mediating hematopoietic failure.
authors.forename: Kamath
authors.initials: K
authors.lastname: Kanchan
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Loughran
mesh_terms: D000941:Antigens / Q000276:immunology; D002999:Clone Cells / Q000276:immunology / Q000473:pathology; D006410:Hematopoiesis; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology*; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
chemical_list: D000941:Antigens