title: Ultrastructural and morphometric characteristics of nerve cells and myelinated fibers in the cerebral cortex after chronic exposure to natural gas containing hydrogen sulfide in low concentrations.
abstract: We studied ultrastructural and morphometric characteristics of nerve cells and myelinated fibers in the cerebral cortex after chronic exposure to natural gas containing hydrogen sulfide in low concentrations. Radioisotope assay revealed activation of protein synthesis in nerve cells after chronic exposure to natural hydrogen sulfide-containing gas in low concentrations (10 mg/m(3)by H2S) for 2 weeks. After 1 month the ultrastructure of myelinated fibers was characterized by sectorial loosening and demyelination.
authors.affiliation: Laboratory of Experimental Cell Pathology, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia.
authors.forename: T G
authors.initials: TG
authors.lastname: Solnyshkova
authors.forename: V A
authors.initials: VA
authors.lastname: Shakhlamov
mesh_terms: D000393:Air Pollutants / Q000633:toxicity*; D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology*; D006862:Hydrogen Sulfide / Q000633:toxicity*; D008297:Male; D008452:Maximum Allowable Concentration; D009186:Myelin Sheath / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure*; D009474:Neurons / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure; D014176:Protein Biosynthesis; D011506:Proteins / Q000187:drug effects; D051381:Rats; D013997:Time Factors; D036401:Toxicity Tests, Chronic
chemical_list: D000393:Air Pollutants; D011506:Proteins; D006862:Hydrogen Sulfide