title: Frosted branch angiitis associated with Harada disease-like manifestations recurs 10 years later.
abstract: OBJECTIVE
  To describe a case with frosted branch angiitis occurring in association with manifestations of Harada disease.
  
  
  METHODS
  A 41-year-old man developed marked iridocyclitis, frosted branch angiitis and retinal white dots, together with serous detachment of the sensory retina in the posterior pole of both eyes.
  
  
  METHODS
  Fluorescein angiography demonstrated multiple retinal pigment epithelial leakage points in the early phase followed by late dye pooling in the serous detachment, consistent with the manifestations of Harada disease. The patient experienced recurrence of the same combination of manifestations 10 years later. On both occasions, he showed mononuclear cell increase and protein elevation in the cerebrospinal fluid on spinal tap.
  
  
  CONCLUSIONS
  Fluorescein angiography and spinal tap supported the diagnosis of Harada disease in the patient. The present patient could be diagnosed as having either Harada disease with frosted branch-like response or frosted branch angiitis with serous retinal detachment as occurs in Harada disease.
authors.affiliation: Department of Ophthalmology, Okayama University Medical School, Okayama City, Japan.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Matsuo
authors.forename: Naoko
authors.initials: N
authors.lastname: Kanata
authors.forename: Masako
authors.initials: M
authors.lastname: Itami
mesh_terms: D000328:Adult; D005451:Fluorescein Angiography; D006801:Humans; D007429:Intraocular Pressure; D015863:Iridocyclitis / Q000175:diagnosis / Q000209:etiology; D008297:Male; D012008:Recurrence; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology; D031300:Retinal Vasculitis / Q000175:diagnosis / Q000209:etiology*; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications* / Q000175:diagnosis; D014792:Visual Acuity