title: High-intensity ultrasound-promoted reformatsky reactions.
abstract: Reformatsky reactions of a phenyl ketone, an alpha-bromoester, zinc dust, and a catalytic amount of iodine in dioxane under high-intensity ultrasound (HIU) irradiation from an ultrasonic probe give high yields of beta-hydroxyesters in short reaction times. A series of alkyl phenyl ketones with increasing steric demands of the alkyl group are evaluated as potential electrophiles for the reactions with several alpha-bromoesters, also having increasing steric demands. The Reformatsky reaction under HIU is found to be concentration dependent.
authors.affiliation: Department of Chemistry and Biochemistry, Texas Tech University, Lubbock 79409, USA.
authors.forename: Nathan A
authors.initials: NA
authors.lastname: Ross
authors.forename: Richard A
authors.initials: RA
authors.lastname: Bartsch