Wave propagation in the atrial myocardium: dispersion properties in the normal state and before fibrillation.
The formalism of wave propagation in passive media is applied to the spread of the electrical excitation in the human atrial myocardium. From an analog of the classical dispersion dependence that is obtained by wavelet decomposition a precursor parameter is calculated that serves to predict fibrillation already before its onset.
Anosov
Oleg
O
Department of Biomedical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg, Turnstrasse 5, D-91054, Erlangen, Germany. oanosov@biomed.uni-erlangen.de
Berdyshev
Sergey
S
Khassanov
Ildar
I
Schaldach
Max
M
Hensel
Bernhard
B
D000200:Action Potentials; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D003198:Computer Simulation; D006325:Heart Atria / Q000503:physiopathology* / Q000601:surgery; D006329:Heart Conduction System / Q000503:physiopathology*; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D008943:Mitral Valve; D008955:Models, Cardiovascular; D012016:Reference Values; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted