[A retrospective morphological analysis of endomyocardial biopsies of myocarditis patients].
A repeated retrospective analysis of histoultrastructure of endomyocardial biopsies of patients with diagnosis of myocarditis and with various life span after manifestation of the first disease symptoms. The most unfavorable sign of prognosis is advanced myocardiocyte necrosis, alterative changes and the degree of interstitial cell reaction. Death of cardiocytes due to apoptosis was not typical for myocarditis and was observed only in several patients from the group with long survival. A new type of cardiomyocyte death--extrusion of the nucleus from the cell--was found in the group with low survival.
Tsyplenkova
V G
VG
L. Myasnikov Institute of Cardiology, 112454, Moscow.
Shvarneva
G G
GG
Branishte
F A
FA
Samko
A N
AN
Naumov
V G
VG
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D019044:Image Cytometry; D008297:Male; D008854:Microscopy, Electron; D009205:Myocarditis / Q000175:diagnosis / Q000473:pathology*; D009206:Myocardium / Q000473:pathology* / Q000648:ultrastructure; D032383:Myocytes, Cardiac / Q000473:pathology / Q000648:ultrastructure; D012189:Retrospective Studies