Cytokines during early pregnancy of mammals: a review.
This article reviews the function of cytokines during early pregnancy of mammals including the human species. Investigations concerning conceptus and other secretory proteins, their meaning for maternal recognition and maintenance of pregnancy, fetal and placental growth and differentiation, adhesion, invasion and implantation are discussed, and differences between laboratory rodents, carnivores, artiodactyls, horses and human beings elucidated and summarized. Finally topics that might be of interest for further research are emphasized.
Schäfer-Somi
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Clinic for Obstetrics, Gynecology and Andrology, University of Veterinary Sciences Vienna, Veterinärplatz 1, A-1210 Vienna, Austria. sabine.schaefer@vu-wien.ac.at
D000818:Animals; D018835:Chaperonin 10; D016207:Cytokines / Q000276:immunology / Q000502:physiology*; D010064:Embryo Implantation / Q000276:immunology / Q000502:physiology; D005260:Female; D006133:Growth Substances / Q000276:immunology / Q000502:physiology; D006801:Humans; D008322:Mammals / Q000276:immunology / Q000502:physiology*; D010455:Peptides / Q000276:immunology / Q000502:physiology; D010920:Placenta / Q000276:immunology / Q000502:physiology; D011247:Pregnancy / Q000276:immunology / Q000502:physiology*; D011255:Pregnancy Maintenance / Q000276:immunology / Q000502:physiology; D011257:Pregnancy Proteins; D011270:Pregnancy, Animal / Q000276:immunology / Q000502:physiology*; D013045:Species Specificity; D013491:Suppressor Factors, Immunologic
D018835:Chaperonin 10; D016207:Cytokines; D006133:Growth Substances; D010455:Peptides; D011257:Pregnancy Proteins; D013491:Suppressor Factors, Immunologic; C025124:early pregnancy factor