AMP-activated protein kinase, super metabolic regulator.
The AMP-activated protein kinase (AMPK) is a metabolic-stress-sensing protein kinase that regulates metabolism in response to energy demand and supply by directly phosphorylating rate-limiting enzymes in metabolic pathways as well as controlling gene expression.
Kemp
B E
BE
St. Vincent's Institute of Medical Research, and Department of Medicine, University of Melbourne, 41 Victoria Parade, Fitzroy, Vic. 3065, Australia. kemp@ariel.unimelb.edu.au
Stapleton
D
D
Campbell
D J
DJ
Chen
Z-P
ZP
Murthy
S
S
Walter
M
M
Gupta
A
A
Adams
J J
JJ
Katsis
F
F
van Denderen
B
B
Jennings
I G
IG
Iseli
T
T
Michell
B J
BJ
Witters
L A
LA
D055372:AMP-Activated Protein Kinases; D000818:Animals; D003920:Diabetes Mellitus / Q000235:genetics; D005786:Gene Expression Regulation; D005947:Glucose / Q000378:metabolism; D006019:Glycolysis; D006801:Humans; D008055:Lipids; D008954:Models, Biological; D008958:Models, Molecular; D009097:Multienzyme Complexes / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D009154:Mutation; D009765:Obesity / Q000235:genetics; D010766:Phosphorylation; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D017434:Protein Structure, Tertiary
D008055:Lipids; D009097:Multienzyme Complexes; D017346:Protein Serine-Threonine Kinases; D055372:AMP-Activated Protein Kinases; D005947:Glucose