Behavior and biology: the prevention of type 2 diabetes.
Type 2 diabetes mellitus (DM), characterized by insulin resistance and a beta-cell secretory defect, appears to result from a number of gene and environmental interactions. There are marked differences in the phenotypic expression of type 2 DM with individuals exhibiting varying levels of insulin resistance and impairments in insulin secretion. Study results indicate that a number of healthy lifestyle behaviors, such as increased physical activity and reduced intake of dietary fat, are associated with decreased development of type 2 DM. This article explores the genetic and environmental factors associated with the development of type 2 DM along with the role of lifestyle modifications in the prevention of this disease.
Quinn
Laurie
L
College of Nursing, University of Illinois at Chicago, Chicago, Illinois, USA.
D003924:Diabetes Mellitus, Type 2 / Q000208:ethnology / Q000235:genetics* / Q000517:prevention & control*; D015444:Exercise; D020022:Genetic Predisposition to Disease; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008957:Models, Genetic; D012307:Risk Factors