title: Multiple trauma in children: critical care overview.
abstract: Multiple trauma is more than the sum of the injuries. Management not only of the physiologic injury but also of the pathophysiologic responses, along with integration of the child's emotional and developmental needs and the child's family, forms the basis of trauma care. Multiple trauma in children also elicits profound psychological responses from the healthcare providers involved with these children. This overview will address the pathophysiology of multiple trauma in children and the general principles of trauma management by an integrated trauma team. Trauma is a systemic disease. Multiple trauma stimulates the release of multiple inflammatory mediators. A lethal triad of hypothermia, acidosis, and coagulopathy is the direct result of trauma and secondary injury from the systemic response to trauma. Controlling and responding to the secondary pathophysiologic sequelae of trauma is the cornerstone of trauma management in the multiply injured, critically ill child. Damage control surgery is a new, rational approach to the child with multiple trauma. The selection of children for damage control surgery depends on the severity of injury. Major abdominal vascular injuries and multiple visceral injuries are best considered for this approach. The effective management of childhood multiple trauma requires a combined team approach, consideration of the child and family, an organized trauma system, and an effective quality assurance and improvement mechanism.
authors.affiliation: Department of Anesthesiology Critical Care Medicine, Childrens Hospital of Los Angeles, 4650 Sunset Boulevard, MS# 12, Los Angeles, CA 90027-6062, USA.
authors.forename: Randall C
authors.initials: RC
authors.lastname: Wetzel
authors.forename: R Cartland
authors.initials: RC
authors.lastname: Burns
mesh_terms: D000138:Acidosis / Q000209:etiology / Q000628:therapy; D002648:Child; D003422:Critical Care / Q000379:methods* / Q000458:organization & administration; D005190:Family; D006801:Humans; D007035:Hypothermia / Q000209:etiology / Q000628:therapy; D009104:Multiple Trauma / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D010348:Patient Care Team; D012151:Resuscitation