[Estimation of myocardial perfusion changes after surgical revasculization with single-photon emission computed tomography].
OBJECTIVE
to estimate myocardial perfusion performing single-photon emission computed tomography before and in early period after coronary artery bypass grafting; to predict results of complete myocardial revascularisation by preoperative perfusion data.


METHODS
Ten patients with stable coronary artery disease and resting left ventricular wall motion abnormalities (mean ejection fraction 37.7+/-6.5%, mean wall motion index 1.89+/-0.32) underwent 99mTc-MIBI myocardial perfusion single-photon emission computed tomography before and in early period (3 and 6 months) after coronary artery bypass grafting. We estimated myocardial perfusion, postoperative recovery and calculated scintigraphic indices.


RESULTS
The mean number of distal anastomoses was 3.5+/-0.9 and all of patients had complete myocardial revascularization. Postoperatively 39 (66.1%) after 3 months and 45 (76.3%) after 6 months of 59 revasculared segments with different degree of myocardial perfusion disorders improved. Postoperative (after 6 months) index of myocardial perfusion recovery was found more than 2 times better than predicted preoperatively, because there was no estimation of hibernating myocardium preoperatively.


CONCLUSIONS
Estimation of myocardial perfusion changes with single-photon emission computed tomography in early postoperative period, especially after 6 months, confirms the excellent and final results of complete surgical myocardial revascularization. Present protocol of myocardial perfusion investigation gives incomplete information in prediction of postoperative results of complete myocardial revascularization. Myocardial perfusion study performed after nitrate administration is the method of choice to predict correct results.
Macys
Antanas
A
Institute for Biomedical Research, Kaunas University of Medicine, Eiveniu 4, 3007 Kaunas, Lithuania. tonis@one.lt
Kinduris
Sarūnas
S
Dumcius
Arimantas
A
Kulakiene
Ilona
I
Babarskiene
Rūta
R
Linoniene
Leonarda
L
D000368:Aged; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003326:Coronary Circulation; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000601:surgery*; D017682:Myocardial Stunning; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon; D016896:Treatment Outcome
D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi