title: [The effect of glucocorticoid on neural system development].
abstract: During the early developmental period of central nerves system, glucocorticoid can influence the activity of hypothalamic-pituitary-adrenocortical axis via glucocorticoid receptors, and modulate the process of neural survival, outgrowth and programming death process; In adult, glucocorticoid can regulate the expression of the factors which correlate with the plasticity of neurons; In aged individual, glucocorticoid can be harmful to nerves under most conditions. Therefore, glucocorticoid plays an important role in the development of neural system.
authors.affiliation: Institute of Psychology, Chinese Academy of Sciences, Beijing 100101.
authors.forename: J F
authors.initials: JF
authors.lastname: Hu
authors.forename: N
authors.initials: N
authors.lastname: Sui
authors.forename: P Z
authors.initials: PZ
authors.lastname: Kuang
authors.forename: L C
authors.initials: LC
authors.lastname: Guan
mesh_terms: D000818:Animals; D001921:Brain / Q000196:embryology / Q000254:growth & development*; D005938:Glucocorticoids / Q000502:physiology*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D010913:Pituitary-Adrenal System / Q000502:physiology; D011965:Receptors, Glucocorticoid / Q000502:physiology*
chemical_list: D005938:Glucocorticoids; D011965:Receptors, Glucocorticoid