[Chiral drug separation by supercritical fluid chromatography].
Because of the high-efficiency, fast separation, low-temperature analysis and applicable to a wide variety of detectors, supercritical fluid chromatography(SFC) is an attractive alternative for chiral drug separation. The development and application of this technique in enantiomer separation are reviewed with 48 references. The separation modes and the choices of experimental condition are discussed.
Li
H
H
Department of the Science of Analysis and Measurement, Wuhan University, Wuhan, 430072.
Hu
X
X
D000319:Adrenergic beta-Antagonists / Q000302:isolation & purification*; D000526:Alprenolol / Q000302:isolation & purification; D000577:Amides / Q000302:isolation & purification; D000596:Amino Acids / Q000302:isolation & purification; D025924:Chromatography, Supercritical Fluid; D013237:Stereoisomerism
D000319:Adrenergic beta-Antagonists; D000577:Amides; D000596:Amino Acids; D000526:Alprenolol