Fusion and fission events in the endocytic pathway of Dictyostelium.
The endocytic pathway in Dictyostelium appears as a short circuit between endocytosis and exocytosis. Within the hour that elapses between internalization of nutrients and release of remnants, digestion by lysosomal enzymes occurs. Meanwhile, the maturing endosome undergoes a complex series of fusion and fission events, which change its character profoundly and which are far from being fully understood. This review attempts to order the dynamic events into a sequence of stages that is most consistent with present knowledge.
Maniak
Markus
M
Abt. Zellbiologie, Universität Kassel, Heinrich-Plett-Str. 40, 34132 Kassel, Germany. maniak@uni-kassel.de
D000818:Animals; D004023:Dictyostelium / Q000166:cytology / Q000502:physiology*; D004705:Endocytosis / Q000502:physiology*; D011992:Endosomes / Q000502:physiology