title: The Xenopus arx gene is expressed in the developing rostral forebrain.
abstract: The human aristaless-related homeobox ( ARX) gene is mutated in several patients with X-linked mental retardation and/or other neurologic pathologies. We report the isolation and expression pattern of a Xenopus arx gene. Similar to other vertebrate arx genes, Xenopus arx is expressed in the developing telencephalon, diencephalon, and floor plate.
authors.affiliation: Center for Molecular and Human Genetics, Children's Research Institute, 700 Children's Drive, Columbus, OH 43026, USA. ELH@pediatrics.ohio-state.edu
authors.forename: Heithem M
authors.initials: HM
authors.lastname: El-Hodiri
authors.forename: Xiu-Lan
authors.initials: XL
authors.lastname: Qi
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Seufert
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox; D018398:Homeodomain Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D016548:Prosencephalon / Q000196:embryology* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D014981:Xenopus / Q000235:genetics*
chemical_list: D018398:Homeodomain Proteins