title: Incidence and clinical features of asymptomatic atrial septal defect in school children diagnosed by heart disease screening.
abstract: The purpose of this study was to investigate the incidence and clinical features of atrial septal defect (ASD) in school children in Japan who were diagnosed by heart disease screening. From 1989 to 1998, a questionnaire, electrocardiography (ECG) and phonocardiogram were obtained from school children when they entered their first year of elementary school (n=86,142) or junior high school (n=80,632). In this program, 33 asymptomatic ASD patients were newly diagnosed (0.020%). The ECG findings showed incomplete right bundle-branch block (79%), right axis deviation (55%), and right ventricular hypertrophy (9%). An ejection systolic murmur was audible in 30 patients (94%) and mid-diastolic murmur in 10 patients (30%). Thirty patients (90%) showed fixed split of second heart sound. Using echocardiography or catheter observation, 31 patients (94%) were judged to require closure of the ASD. Although the medical care is widely available in Japan, undetected ASD patients were not rare and importantly, most of them required closure of the defect even if they were asymptomatic.
authors.affiliation: Department of Pediatrics, Kurume University School of Medicine, Japan. QZE05346@nifty.com
authors.forename: Hiromi
authors.initials: H
authors.lastname: Muta
authors.forename: Teiji
authors.initials: T
authors.lastname: Akagi
authors.forename: Kimiyasu
authors.initials: K
authors.lastname: Egami
authors.forename: Jun
authors.initials: J
authors.lastname: Furui
authors.forename: Yoko
authors.initials: Y
authors.lastname: Sugahara
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ishii
authors.forename: Toyojiro
authors.initials: T
authors.lastname: Matsuishi
mesh_terms: D000293:Adolescent; D002037:Bundle-Branch Block; D002648:Child; D004562:Electrocardiography; D005260:Female; D006337:Heart Murmurs; D006344:Heart Septal Defects, Atrial / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D006801:Humans; D017380:Hypertrophy, Right Ventricular; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods*; D011795:Surveys and Questionnaires