title: Inductively coupled transmission of neuro-active signals: analysis of optimal parameters.
abstract: Fifteen parameters that play a role in the optimal transmission of therapeutic signals by inductively coupled implantable neurostimulator have been investigated. For this purpose, at first, a model of the system was constructed from which the system transfer function was obtained. Then, the relationship between the transfer gain and each parameter was evaluated using mathematical equations and a specifically built computer program. This study showed that the gain could be increased selecting small values for some parameters (the number of active coil windings, first radii of inner and outer paths of the core, heights of the core base and windings, position under the skin, internal resistances of the active and passive coils, tissue impedance between the contacts of electrode), and high values for the others (the number of passive coil windings, second radii of inner and outer paths of the core, frequency of the signal, relative magnetic permeability of the core). Critical saturation values were another considerable point. The nearest commercially available standard values should be preferred in practical applications.
authors.affiliation: Faculty of Medicine, Department of Biophysics, Univeristy of Gaziantep, 27310 Kampus, Gaziantep, Turkey. tulgar@gantep.edu.tr
authors.forename: Metin
authors.initials: M
authors.lastname: Tulgar
authors.forename: Omer Muhammet
authors.initials: OM
authors.lastname: Soysal
mesh_terms: D003198:Computer Simulation; D017097:Electric Impedance; D004599:Electric Stimulation Therapy / Q000295:instrumentation* / Q000379:methods*; D004567:Electrodes, Implanted; D004574:Electromagnetic Fields; D004581:Electronics; D004867:Equipment Design / Q000379:methods*; D008954:Models, Biological; D009474:Neurons / Q000502:physiology*; D019736:Prostheses and Implants; D011786:Quality Control; D012879:Skin Physiological Phenomena; D009435:Synaptic Transmission / Q000502:physiology; D013686:Telemetry / Q000295:instrumentation / Q000379:methods; D004561:Transcutaneous Electric Nerve Stimulation / Q000295:instrumentation / Q000379:methods