title: Pleomorphic vulvar leiomyoma with local invasive behavior.
abstract: A case of pleomorphic leiomyoma in Bartholin gland's area in a 26-year-old woman is reported. After diagnostic treatment, primary excision was done. A large, solid tumor 10 x 7.5 cm was extirpated. The tumor showed locally invasive behavior, which suggested a malignant tumor of Bartholin gland, because of it's localization and outlook. Pathohistological examination and immunohistochemical reactions proved that it was a mesenchymal tumor of smooth muscle origin with marked polymorphism, without mitosis, with a myxoid stroma and with biological aggressivity, and the possibility of local recurrence. Thus, a second more radical surgical procedure, was performed. In the excised tissue, no residual tumor was found and all lymph nodes were negative.
authors.affiliation: Department for Gynecology and Obstetrics University Hospital Osijek, Osijek, Croatia.
authors.forename: Z
authors.initials: Z
authors.lastname: Topolovec
authors.forename: M
authors.initials: M
authors.lastname: Mrcela
authors.forename: M
authors.initials: M
authors.lastname: Milojković
authors.forename: S
authors.initials: S
authors.lastname: Sijanović
authors.forename: J
authors.initials: J
authors.lastname: Topolovec
authors.forename: D
authors.initials: D
authors.lastname: Curzik
authors.forename: Z
authors.initials: Z
authors.lastname: Hrgović
mesh_terms: D000328:Adult; D001472:Bartholin's Glands / Q000473:pathology*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology*; D009361:Neoplasm Invasiveness; D014846:Vulvar Neoplasms / Q000473:pathology*