title: Prenatal therapy for obstructive uropathy.
abstract: The increasing use of routine prenatal imaging and diagnosis has provided a better understanding of the natural history of obstructive uropathy. Fortunately, most disorders portend little clinical significance prenatally, although a select subset can incur irreversible renal injury and pulmonary hypoplasia depending on the onset, duration, severity, and level of obstruction. In these cases, timely antenatal evaluation and prenatal intervention can provide an optimal postnatal outcome. The natural history, evaluation, and management of fetal obstructive uropathies are discussed.
authors.affiliation: The Fetal Treatment Center, Department of Surgery, Division of Pediatric Surgery, University of California, San Francisco, 513 Parnassus Avenue, Room HSW 1601, San Francisco, California 94143-0570, USA.
authors.forename: KuoJen
authors.initials: K
authors.lastname: Tsao
authors.forename: Craig T
authors.initials: CT
authors.lastname: Albanese
mesh_terms: D000818:Animals; D004108:Dilatation, Pathologic; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D023421:Models, Animal; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014517:Ureteral Obstruction / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D014524:Urethral Obstruction / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D014551:Urinary Tract / Q000473:pathology