title: Effect of anatomic, procedural, and dosimetric variables on urinary retention after permanent iodine-125 prostate brachytherapy.
abstract: OBJECTIVE
  To correlate anatomic, procedural, and dosimetric parameters with the rate of intermittent self-catheterization (ISC).
  
  
  METHODS
  The records of 402 patients with a median age of 69 years treated with 125I prostate seed implantation from 1996 to 2001 were reviewed for the use of ISC. The records were examined for the preimplant factors: prostate volume, use of androgen deprivation, and prostate length. The intraprocedural factor reviewed was the number of needles used. The following postimplant information was also collected: preimplant transrectal ultrasound-generated prostate volume/postimplant computed tomography-generated prostate volume ratio, V100, V150, V200, V300, V400, D90, and D100. Correlation was assessed using logistic regression analysis.
  
  
  RESULTS
  Forty-four patients had to use ISC (10.9%). The mean and median duration of ISC was 11.9 and 6 weeks, respectively. From univariate analysis, prostate length and prostate volume were found to be statistically significant predictors of ISC after 125I prostate seed implantation with a P value of 0.0002 and 0.0042, respectively. With multivariate analysis, only prostate length was a statistically significant predictor of ISC use after 125I prostate seed implantation (P = 0.0095).
  
  
  CONCLUSIONS
  Prostate length is an important predictor of ISC after 125I prostate seed implantation.
authors.affiliation: Department of Radiation Oncology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
authors.forename: Mohamed A
authors.initials: MA
authors.lastname: Elshaikh
authors.forename: Kenneth
authors.initials: K
authors.lastname: Angermeier
authors.forename: James C
authors.initials: JC
authors.lastname: Ulchaker
authors.forename: Eric A
authors.initials: EA
authors.lastname: Klein
authors.forename: Mark A
authors.initials: MA
authors.lastname: Chidel
authors.forename: Stephen
authors.initials: S
authors.lastname: Mahoney
authors.forename: D Allan
authors.initials: DA
authors.lastname: Wilkinson
authors.forename: Chandana A
authors.initials: CA
authors.lastname: Reddy
authors.forename: Jay P
authors.initials: JP
authors.lastname: Ciezki
mesh_terms: D000368:Aged; D001918:Brachytherapy / Q000009:adverse effects*; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D011467:Prostate / Q000033:anatomy & histology / Q000000981:diagnostic imaging* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D012648:Self Care / Q000706:statistics & numerical data; D014463:Ultrasonography; D014546:Urinary Catheterization / Q000706:statistics & numerical data; D016055:Urinary Retention / Q000209:etiology* / Q000628:therapy*
chemical_list: D007457:Iodine Radioisotopes