[The fungicidal effect of the antibacterial peptide CM4 from Chinese silkworm on Fusaricum moniliforme].
The antibacterial peptide CM4 inhibits growth of conidia of Fusaricum moniliforme. The observation by using the electron microscope showed that some cells were empty and interior structure twisted into helix. Conidia cells in control group were in good condition, normally grew up. The fungal conidia treated with the antibacterial peptide CM4, then confocal laser scanning microscope were performed. As a result, it was showed that FITC-labeled peptide assembled in cells, centre of which had more peptides than two ends. Then conidia split, became empty. Finally the cells plasma membrane disintegrated and died, lead to small fragments.
Xu
J S
JS
School of Life Science, Nanjing Nomorl University, Nanking 210097.
Zhuang
S Q
SQ
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D023181:Antimicrobial Cationic Peptides / Q000494:pharmacology*; D012831:Bombyx; D005670:Fusarium / Q000187:drug effects / Q000648:ultrastructure*; D018613:Microscopy, Confocal; D013172:Spores, Fungal / Q000187:drug effects / Q000648:ultrastructure*
D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides