[Preparation, characterization and evaluation of cellulose tris (3,5-dimethylphencarbamate) chiral stationary phase].
With the deposition of cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC) on aminopropylated silica gel (mean particle size, 5 microns; pore size, 13 nm; surface area, 110 m2/g) by using two different methods (evaporation and precipitation), two chiral stationary phases (CSP1 and CSP2) characterized by elemental analysis and scanning electron micrography were obtained. They were also evaluated by using seven racemic compounds with n-hexane/ethanol(95/5, V/V) and n-hexane/2-propanol (90/10, V/V) as mobile phases. The results showed that the chiral stationary phase CSP1 obtained by the evaporation method had better efficiency and chiral resolution ability than CSP2 by the precipitation method.
Hou
J G
JG
College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China. houjg@nwnu.edu.cn
Deng
Q L
QL
Meng
X R
XR
Liu
H L
HL
Yang
W
W
Mo
Z L
ZL
Gao
J Z
JZ
D001573:Benzoin / Q000032:analysis* / Q000302:isolation & purification; D002219:Carbamates; D002482:Cellulose / Q000031:analogs & derivatives*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D005069:Evaluation Studies as Topic; D048448:Phenylcarbamates; D010626:Phenylethyl Alcohol / Q000032:analysis* / Q000302:isolation & purification; D013237:Stereoisomerism
D002219:Carbamates; D048448:Phenylcarbamates; C065943:cellulose tris-3,5-dimethylphenyl-carbamate; D002482:Cellulose; D001573:Benzoin; D010626:Phenylethyl Alcohol