title: [The effect of pyrophosphate analogues on the inorganic pyrophosphatase from Escherichia coli].
abstract: The effect of inorganic pyrophosphate analogues on the enzymic activity of inorganic pyrophosphatase from E. coli was studied. Hypophosphoric and diphosphonic acids were shown to inhibit inorganic pyrophosphatase, whereas pyrophosphorous acid exerts almost no effect on the hydrolysis of inorganic pyrophosphate. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2002, vol. 28, no. 6; see also http://www.maik.ru.
authors.affiliation: Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, GSP Moscow, 119991 Russia. chernov@imb.imb.ac.ru
authors.forename: N F
authors.initials: NF
authors.lastname: Zakirova
authors.forename: A V
authors.initials: AV
authors.lastname: Ivanov
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Skoblov
authors.forename: M K
authors.initials: MK
authors.lastname: Kukhanova
mesh_terms: D011756:Diphosphates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D004926:Escherichia coli / Q000201:enzymology*; D006868:Hydrolysis; D043564:Inorganic Pyrophosphatase; D011755:Pyrophosphatases / Q000037:antagonists & inhibitors / Q000737:chemistry*
chemical_list: D011756:Diphosphates; D004791:Enzyme Inhibitors; D011755:Pyrophosphatases; D043564:Inorganic Pyrophosphatase