[Determination of bifonazole in cream by high performance liquid chromatography].
An accurate method for the determination of bifonazole in cream is described. The analytical column was packed with Hypersil ODS. The mobile phase was a mixture of 0.08 mol/L aqueous triethylamine (TEA) phosphate solution(pH 7.0)-acetonitrile-methanol (20:10:70, V/V) and the detection wavelength was 254 nm. This method is simple, accurate and can be used for the quality control of bifonazole in cream.
Guo
X J
XJ
Shenyang Pharmaceutical University, Shenyang 110015, China.
Wei
Z Y
ZY
Li
F M
FM
D000935:Antifungal Agents / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D007093:Imidazoles / Q000032:analysis*; D009824:Ointments
D000935:Antifungal Agents; D007093:Imidazoles; D009824:Ointments; C036596:bifonazole