[Ximedon-electrophoresis in rehabilitation of patients with systemic scleroderma].
A double blind placebo-controlled trial performed in 56 patients with scleroderma systematica showed effectiveness of a domestic drug ximedon--a pirimidine compound--applied during electrophoresis on the affected skin, limbs. The addition of ximedon-electrophoresis to rehabilitation program for scleroderma systematica improved the condition in 77.8%, microhemocirculation in 72.2%, reduced the area of the affected skin by 9.8% (p < 0.05), skin induration in 55.6% of patients.
Salikhov
I G
IG
Bodrova
R A
RA
Ziganshina
L E
LE
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D006801:Humans; D007478:Iontophoresis / Q000379:methods*; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D011743:Pyrimidines / Q000008:administration & dosage / Q000627:therapeutic use*; D012595:Scleroderma, Systemic / Q000503:physiopathology / Q000534:rehabilitation*; D013817:Thermography; D016896:Treatment Outcome
D000276:Adjuvants, Immunologic; D011743:Pyrimidines; C069705:xymedon