title: Synthesis of milbemycins alpha9, alpha10, alpha11, alpha12, alpha14, alpha15, alpha20, alpha21, alpha22, alpha23, alpha26, alpha27, delta(2,3),delta(4,26)-milbemycins A3, A4 from milbemycins A3, A4, and their acaricidal activities.
abstract: Chemical derivation methods to prepare 26-acyloxy and 26-hydroxymilbemycins, which had been reported as natural products, milbemycins alpha9, alpha10, alpha11, alpha12, alpha14, alpha15, alpha20, alpha21, alpha22, alpha23, alpha26, alpha27 from milbemycins A3, A4 were reported. Delta(2,3),delta(4,26)-milbemycins A3, A4, which had also been reported as natural products, were further prepared from milbemycins A3, A4. Their acaricidal activities were also assessed against the organophosphorus-sensitive two-spotted spider mite (Tetranychus urticae) on primary leaves of cowpea plants (Vigna sinesis Savi species) by spraying.
authors.affiliation: Agroscience Research Laboratories, Crop Protection Company, Sankyo Co. Ltd. 1041 Yasu, Yasu-cho, Yasu-gun, Shiga 520-2342, Japan. tukiya@yasu.sankyo.co.jp
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsukiyama
authors.forename: Hisaki
authors.initials: H
authors.lastname: Kajino
authors.forename: Fumie
authors.initials: F
authors.lastname: Kajino
authors.forename: Satoru
authors.initials: S
authors.lastname: Furuta
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Tsukamoto
authors.forename: Kazuo
authors.initials: K
authors.lastname: Sato
authors.forename: Ayako
authors.initials: A
authors.lastname: Kinoshita
authors.forename: Reiji
authors.initials: R
authors.lastname: Ichinose
authors.forename: Keiji
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000737:chemistry; D007887:Fabaceae; D007306:Insecticides / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000737:chemistry; D018942:Macrolides; D018515:Plant Leaves; D040102:Tetranychidae
chemical_list: D000900:Anti-Bacterial Agents; D007306:Insecticides; D018942:Macrolides; C027837:moxidectin