title: Nano-kinetics of probe-particles in solution visualized by a pin-fiber video scope.
abstract: The nano-kinetics of colloidal particles and living cells with the colloidal particles were visualized by a newly developed video scope. The system of the new video scope has a feature of fine controlling the illumination conditions by using a single optical fiber. This characteristic enables one to obtain clear images of living cells and the motions of colloidal particles by light-scattering effects. In the experiments, RBL-2H3 cells and gold colloidal particles were observed. Scattering images with high contrast and a dark background like in dark-field observations could be attained. In the experiments, a pulsed laser was also applied. The results obtained in this study could validate the effectiveness and possibility of a new video scope for applications to biological and biomedical fields.
authors.affiliation: Graduate School of Medical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Suzuto
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Hirakawa
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Ohnishi
authors.forename: Shinji
authors.initials: S
authors.lastname: Tachino
authors.forename: Tomoteru
authors.initials: T
authors.lastname: Shingaki
authors.forename: Edward M
authors.initials: EM
authors.lastname: Eyring
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Masujima
mesh_terms: D000818:Animals; D002460:Cell Line; D007700:Kinetics; D008853:Microscopy / Q000379:methods*; D036103:Nanotechnology; D012996:Solutions
chemical_list: D012996:Solutions