The influence of spontaneous termination of atrial fibrillation on P wave-triggered signal-averaged electrocardiogram.
BACKGROUND
Prolongation of total filtered P wave duration (Ad) and low root mean square voltages for the last 20 ms of the P wave (LP20) on a P wave-triggered signal-averaged electrocardiogram (PSAECG) are typically observed in paroxysmal atrial fibrillation (PAF) patients. A shortening of atrial refractoriness and intra-atrial conduction delay (atrial remodeling) have been shown to occur in response to PAF. We, therefore, investigated the effects of spontaneous termination of PAF on the parameters of PSAECG.


METHODS
We measured the Ad, LP20 and left atrial (LA) diameter by ultrasonic echocardiography before, within 1 h after, and 3 and 12 months after PAF termination in patients with no structural heart disease (n=11).


RESULTS
The PAF duration was 16+/-5 h. The Ads before, within 1 h after, and 3 and 12 months after PAF were 137+/-4, 148+/-4, 137+/-6, and 135+/-7 ms, respectively. The Ad within 1 h after PAF was significantly (P<0.01) longer than at the other three acquisition points. Although the LP20 within 1 h after PAF termination was not significantly different from the other three points, the change in LP20 (within 1 h after PAF-before PAF, -1.1+/-0.4 microV) in the long PAF duration group was significantly (P<0.05) greater than that of the short PAF duration group. LA diameter was unchanged at all points.


CONCLUSIONS
These data suggest that PAF results in prolongation of Ad after termination of PAF.
Kurogouchi
Fumio
F
Second Department of Internal Medicine, Shinshu University, School of Medicine, 3-1-1 Asahi, Matsumoto, 390-8621, Nagano-ken, Japan.
Tomita
Takeshi
T
Hanaoka
Takeshi
T
Usui
Tatsuya
T
Miyashita
Toyohisa
T
Aruga
Masakazu
M
Katagiri
Yuuichi
Y
Takei
Manabu
M
Owa
Mafumi
M
Kiyosawa
Kendo
K
D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D018780:Body Surface Potential Mapping; D004452:Echocardiography / Q000379:methods; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011336:Probability; D011446:Prospective Studies; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D018709:Statistics, Nonparametric; D013614:Tachycardia, Paroxysmal / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D020257:Ventricular Remodeling / Q000502:physiology*
D000889:Anti-Arrhythmia Agents