title: Diffuse lamellar keratitis 6 months after uneventful laser in situ keratomileusis.
abstract: OBJECTIVE
  Diffuse lamellar keratitis after laser in situ keratomileusis (LASIK) typically occurs between 1 and 7 days after the procedure, and its etiologic factor(s) remain unknown.
  
  
  METHODS
  We describe a case of diffuse lamellar keratitis 6 months after uneventful LASIK in a 25-year-old woman.
  
  
  RESULTS
  Slit-lamp microscopy showed a diffuse infiltrate confined to the interface, extending to the visual axis, with no other relevant findings. Late on-set diffuse lamellar keratitis was our provisional diagnosis and treatment with topical corticosteroids was instituted, with rapid response and improvement of the clinical signs and symptoms.
  
  
  CONCLUSIONS
  This case supports the theory that a previously inert inciting agent could cause a delayed toxic or inflammatory response of the cornea several months after surgery.
authors.affiliation: Department of Refractive Surgery, Instituto Oftalmológico de Alicante, Alicante, Spain.
authors.forename: José I
authors.initials: JI
authors.lastname: Belda
authors.forename: Alberto
authors.initials: A
authors.lastname: Artola
authors.forename: Jorge
authors.initials: J
authors.lastname: Alió
mesh_terms: D000328:Adult; D003315:Cornea / Q000187:drug effects / Q000473:pathology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000209:etiology*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D009216:Myopia / Q000601:surgery; D011239:Prednisolone / Q000627:therapeutic use; D013997:Time Factors; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone