Efficient and general synthetic method for preparing oligoenynes with either trans- or cis-olefinic configuration.
[reaction: see text] Efficient and practical synthesis of a variety of 1-iodo-4-trimethylsilylbut-1-en-3-yne derivatives with trans- and cis-olefinic configuration, and their repeated use as building blocks for the synthesis of trans- and cis-oligoenynes, respectively, are described.
Takayama
Yuuki
Y
Department of Biomolecular Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan.
Delas
Christophe
C
Muraoka
Kenji
K
Sato
Fumie
F