Mycophenolate mofetil may serve as a steroid-sparing agent for sarcoidosis.
Sarcoidosis is an inflammatory disease with potentially severe mucocutaneous manifestations. Mycophenolate mofetil (MMF) is an immunosuppressive drug extensively used in organ transplantation. Its use has been rapidly expanded into autoimmune and inflammatory diseases. We report the first successful and safe use of MMF in five patients with sarcoidosis.
Kouba
D J
DJ
Department of Dermatology, Division of Immunodermatology, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Research Building, Suite 771, Baltimore, MD 21205, USA.
Mimouni
D
D
Rencic
A
A
Nousari
H C
HC
D000328:Adult; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004351:Drug Resistance; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use*; D012507:Sarcoidosis / Q000188:drug therapy*; D012871:Skin Diseases / Q000188:drug therapy*
D003879:Dermatologic Agents; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid