title: 3,7-bis(dialkylamino)phenothiazin-5-ium derivatives: biomedical applications and biological activity.
abstract: The light-induced reactions of 3,7-bis(dialkylamino)phenothiazin-5-ium compounds with biological substrates are briefly discussed. Their biomedical applications, in particular those related with biological staining, interaction with proteins and antiviral, antibacterial and antitumour activity are reviewed.
authors.affiliation: Departamento de Química, Universidade do Minho, 4700-320 Braga, Portugal. jmoura@quimica.uminho.pt
authors.forename: J C V P
authors.initials: JC
authors.lastname: Moura
authors.forename: N
authors.initials: N
authors.lastname: Cordeiro
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000737:chemistry / Q000627:therapeutic use; D004396:Coloring Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008751:Methylene Blue / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000494:pharmacology*; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D004396:Coloring Agents; C103428:3,7-bis(diethylamino)phenothiazin-5-ium; D008751:Methylene Blue