[Modification of the surface of prosthetic valve material by LGDP for protection against microbial adhesion].
This study aimed at the surface modification of prosthetic valve materials by means of cold glow discharge plasma. Orthogonal design was adopted to select the optimal scheme by the experiments of the singular factor, such as output power, gas flow rate, treatment time etc. The PEG-200 was introducted to the surface. Grafting a layer of heparin onto the surface; coating a layer of PEG-like onto the surface first, and then the grafting heparin. Comparing the adhesive amounts of staphylococcus epidermidis (SE), the adhesive curves for Dacron, which was treated by the above methods; the last one is the best.
Wan
C
C
Sichuan Univ, Chengdu 610065.
Duan
Y
Y
Zhang
E
E
Wu
G
G
Ran
J
J
Huang
Y
Y
Yue
Y
Y
D001422:Bacterial Adhesion; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D006350:Heart Valve Prosthesis / Q000382:microbiology*; D006493:Heparin; D008422:Materials Testing; D011092:Polyethylene Glycols; D013212:Staphylococcus epidermidis / Q000502:physiology
D001672:Biocompatible Materials; D011092:Polyethylene Glycols; D006493:Heparin