A quantitative structure-function relationship for the Photosystem II reaction center: supermolecular behavior in natural photosynthesis.
Light-induced charge separation is the primary photochemical event of photosynthesis. Efficient charge separation in photosynthetic reaction centers requires the balancing of electron and excitation energy transfer processes, and in Photosystem II (PSII), these processes are particularly closely entangled. Calculations that treat the cofactors of the PSII reaction center as a supermolecular complex allow energy and electron transfer reactions to be described in a unified way. This calculational approach is shown to be in good agreement with experimentally observed energy and electron transfer dynamics. This supermolecular view also correctly predicts the effect of changing the redox potentials of cofactors by site-directed mutagenesis, thus providing a unified and quantitative structure-function relationship for the PSII reaction center.
Barter
Laura M C
LM
Department of Chemistry, Imperial College, London SW7 2AY, United Kingdom.
Durrant
James R
JR
Klug
David R
DR
D001419:Bacteria / Q000378:metabolism; D018407:Bacterial Physiological Phenomena; D004583:Electrons; D007700:Kinetics; D008954:Models, Biological; D015233:Models, Statistical; D009010:Monte Carlo Method; D010788:Photosynthesis; D045322:Photosynthetic Reaction Center Complex Proteins; D045332:Photosystem II Protein Complex; D018521:Plant Physiological Phenomena; D013053:Spectrophotometry; D013329:Structure-Activity Relationship; D013997:Time Factors
D045322:Photosynthetic Reaction Center Complex Proteins; D045332:Photosystem II Protein Complex