Trace amine receptors as targets for novel therapeutics: legend, myth and fact.
Trace amines are attracting attention as neurotransmitters because they are believed to play a role in human disorders such as schizophrenia, depression, attention deficit disorder and Parkinson's disease. Research to date is promising and confirms the need for continuing work to forge the way for new drug discovery.
Branchek
Theresa A
TA
Synaptic Pharmaceutical Corporation, 215 College Road, Paramus, NJ 07652-1431, USA. tbranchek@synapticcorp.com
Blackburn
Thomas P
TP
D000818:Animals; D001679:Biogenic Amines / Q000819:agonists / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy / Q000378:metabolism; D009422:Nervous System Diseases / Q000188:drug therapy / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000819:agonists / Q000037:antagonists & inhibitors / Q000627:therapeutic use*
D001679:Biogenic Amines; D011956:Receptors, Cell Surface