title: The semantic category effect increases with worsening anomia in Alzheimer's type dementia.
abstract: A large number of patients (n=72) with probable Alzheimer's type dementia (DAT) and mild cognitive impairment (MCI) carried out a picture naming task which comprised stimuli from biological and nonbiological categories. The results were stratified into five ranges of overall naming ability. Every group except those with scores within the range of elderly normal individuals demonstrated better nonbiological naming than biological naming, an effect which increased with worsening impairment. In general, patients diagnosed with other dementia (n=15) did not fit well within the pattern of the DAT/MCI participants, except those known to have a significant semantic impairment. A category effect favoring nonbiological items appears to be robust and produce a predictable pattern across progressive levels of impairment in AD.
authors.affiliation: Bloomfield Centre for Research in Aging, Lady Davis Institute for Medical Research, and Jewish General Hospital Memory Clinic, McGill University, Montréal, Canada H3T 1E2. christine.whatmough@mail.mcgill.ca
authors.forename: C
authors.initials: C
authors.lastname: Whatmough
authors.forename: H
authors.initials: H
authors.lastname: Chertkow
authors.forename: S
authors.initials: S
authors.lastname: Murtha
authors.forename: D
authors.initials: D
authors.lastname: Templeman
authors.forename: L
authors.initials: L
authors.lastname: Babins
authors.forename: N
authors.initials: N
authors.lastname: Kelner
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000150:complications*; D000849:Anomia / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D012660:Semantics; D012680:Sensitivity and Specificity