In search of lipid translocases and their biological functions.
In plasma membranes, lipids distribute asymmetrically across the bilayer, a process that requires proteins. Recent work identified novel lipid translocators in yeast, and their activity was functionally correlated to endocytosis, thus boosting investigations on identity, mechanism, and function of lipid translocases.
Hoekstra
Dick
D
Department of Membrane Cell Biology, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands.
van IJzendoorn
Sven C D
SC
D001692:Biological Transport; D002352:Carrier Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000737:chemistry* / Q000201:enzymology / Q000378:metabolism*; D004705:Endocytosis; D050356:Lipid Metabolism; D008565:Membrane Proteins / Q000378:metabolism; D049294:Phospholipid Transfer Proteins; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000201:enzymology / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism
D002352:Carrier Proteins; D008565:Membrane Proteins; D049294:Phospholipid Transfer Proteins; D029701:Saccharomyces cerevisiae Proteins