Selected local and peripheral intereactions of some cytokines in etiopathogenesis of preeclampsia.
In accordance with presented results and clinical observation it should be assumed that basic phenomena resulting in clinical sign of preeclampsia take place already in implantation and embryogenesis. Abnormal trophoblastic infiltrations and changes in vascular endothelium functioning occur due to disturbed interaction of cytokines and growth factors. Pathologies present in endothelial cells (EC) become the cause of blood overcoagulation and hypertension and promote other clinical symptoms of preeclampsia.
Bielecki
Dariusz A
DA
Terlikowski
Sławomir J
SJ
Południewski
Grzegorz
G
Bielecki
Marian
M
D015415:Biomarkers / Q000032:analysis; D016207:Cytokines / Q000378:metabolism*; D016228:Endothelial Growth Factors / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000209:etiology* / Q000503:physiopathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D018570:Risk Assessment; D012680:Sensitivity and Specificity
D015415:Biomarkers; D016207:Cytokines; D016228:Endothelial Growth Factors