[Determination of benzo[a]pyrene in mainstream smoke by solid-phase extraction and gas chromatography-mass spectrometry].
A novel method is suggested for the determination of benzo[a]pyrene in mainstream smoke. Extraction of Cambridge pads was cleaned up with methanol/n-heptane extraction system and silica solid-phase extraction (SPE). The eluted solution containing benzo[a]pyrene was evaporated gently to complete dryness with N2 flow, then reconstituted in 200 microL ethyl acetate for determination with gas chromatography-mass spectrometry selected ion monitoring (SIM). The proposed method had good results and precision for the separation of pyrene in complex matrices.
Liu
Jian-Fu
JF
Institute of Science and Technology, Changsha Cigarette Factory, Changsha 410014, China.
Yu
Xin
X
Liu
De-Hua
DH
Tan
Hai-Feng
HF
Tan
Ying
Y
Zhou
Yu
Y
D001564:Benzo(a)pyrene / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D012906:Smoke / Q000032:analysis*; D012997:Solvents; D014026:Nicotiana
D012906:Smoke; D012997:Solvents; D001564:Benzo(a)pyrene