A case report of difficult diagnosis in the patient with advanced laryngeal tuberculosis.
We report a patient with severe laryngeal tuberculosis (LTB) involving thyroid cartilage and combined with whole-bone metastasis. A 57-year-old male had presented only with hoarseness. Radiological findings were indicative of suspected metastasis from a malignant tumor. However, tuberculosis was considered by histopathological findings, and so sputum samples were tested for acid-fast bacilli and purified protein derivatives of tuberculin in order to detect the presence of LTB. A polymerase chain reaction confirmed the diagnosis. Anti-tuberculous medications were effective in resolving the hoarseness, and the removal of the mass in the right wing of thyroid cartilage was confirmed by computed tomography (CT).
Kenmochi
Mutsumi
M
Department of Otolaryngology, St. Marianna University School of Medicine, Yokohama City Seibu Hospital, 1197-1, Yasashi-chou, Asahi-ku, 241-0811, Yokohama, Japan. mkenmochi@marianna-u.ac.jp
Ohashi
Toru
T
Nishino
Hirohito
H
Sato
Sigeki
S
Tanaka
Yasuhiko
Y
Koizuka
Izumi
I
Shinagawa
Toshihito
T
D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D002574:Cervical Vertebrae / Q000473:pathology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D006685:Hoarseness / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D013957:Thyroid Cartilage / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014399:Tuberculosis, Spinal / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014827:Vocal Cords / Q000473:pathology
D000995:Antitubercular Agents