title: Intestinal pseudoobstruction as a paraneoplastic syndrome in ganglioneuroblastoma.
abstract: Intestinal pseudoobstruction may be part of a paraneoplastic syndrome. We report a teenage girl with ganglioneuroblastoma who presented with severe constipation. The intestinal pseudoobstruction was presumed to be due to inflammation of the myenteric plexus with destruction of the ganglion cells caused by antineuronal nuclear antibodies (ANNA or Anti-Hu).
authors.affiliation: Department of Paediatric Surgery, University Children's Hospital, Zurich, Switzerland. bwildhab@med.umich.edu
authors.forename: B
authors.initials: B
authors.lastname: Wildhaber
authors.forename: F
authors.initials: F
authors.lastname: Niggli
authors.forename: T
authors.initials: T
authors.lastname: Stallmach
authors.forename: U
authors.initials: U
authors.lastname: Willi
authors.forename: U G
authors.initials: UG
authors.lastname: Stauffer
authors.forename: P
authors.initials: P
authors.lastname: Sacher
mesh_terms: D000293:Adolescent; D003248:Constipation / Q000209:etiology; D005260:Female; D018305:Ganglioneuroblastoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007414:Intestinal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D007418:Intestinal Pseudo-Obstruction / Q000209:etiology* / Q000601:surgery; D009197:Myenteric Plexus / Q000503:physiopathology; D009364:Neoplasm Recurrence, Local; D010166:Palliative Care; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*