title: Synthesis of an amino-functionalized model of the Fe-only hydrogenase active site.
abstract: A dinuclear 2Fe2S mimic 6 of the active site of the Fe-only hydrogenases has been synthesized. Complex 6 contains a free amino group which enables linkage to a protein backbone or to a redox active species for the study of electron transfer processes in proteins or in supramolecular systems. The structures of the complex 6 and its Boc-protected precursor 5 could be verified by X-ray crystallography.
authors.affiliation: Department of Organic Chemistry, Arrhenius Laboratory Stockholm University, Stockholm, Sweden.
authors.forename: Szabolcs
authors.initials: S
authors.lastname: Salyi
authors.forename: Mikael
authors.initials: M
authors.lastname: Kritikos
authors.forename: Björn
authors.initials: B
authors.lastname: Akermark
authors.forename: Licheng
authors.initials: L
authors.lastname: Sun
mesh_terms: D000588:Amines / Q000737:chemistry*; D001665:Binding Sites; D006864:Hydrogenase / Q000138:chemical synthesis* / Q000737:chemistry* / Q000378:metabolism; D007501:Iron / Q000378:metabolism*; D008958:Models, Molecular; D018716:Molecular Mimicry; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D000588:Amines; D007501:Iron; D006864:Hydrogenase