title: Imported viral haemorrhagic fever with a potential for person-to-person transmission: review and recommendations for initial management of a suspected case in Belgium.
abstract: Viral haemorrhagic fevers are caused by a wide range of viruses. There are 4 types of viruses well known to spread from person to person and able to cause nosocomial outbreaks with a high case fatality rate: an arenavirus (Lassa fever and more exceptionally the Junin and Machupo virus), a bunyavirus (Crimean-Congo haemorrhagic fever) and the Filoviridae (Ebola and Marburg viruses). So far there have been only a limited number of imported cases of viral haemorrhagic fever in industrialized countries. In recent years an increasing number of outbreaks of filovirus infections have occurred in Africa and in 2000 5 cases of Lassa fever were brought from Sierra Leone to Europe. Therefore European physicians should consider the possibility of a viral haemorrhagic fever in an acutely ill patient just returning from Africa or South-America with fever for which there is no obvious cause. Such patients should be questioned for risk factors for viral haemorrhagic fever. Using universal precautions for handling blood and body fluids and barrier nursing techniques there is little risk that if a patient with viral haemorrhagic fever arrives in Belgium there will be secondary cases.
authors.affiliation: Departement Klinische Wetenschappen, Instituut voor Tropische Geneeskunde Nationalestraat 155, B-2000 Antwerpen. bcoleb@itg.be
authors.forename: R
authors.initials: R
authors.lastname: Colebunders
authors.forename: M
authors.initials: M
authors.lastname: Van Esbroeck
authors.forename: M
authors.initials: M
authors.lastname: Moreau
authors.forename: M
authors.initials: M
authors.lastname: Borchert
mesh_terms: D001530:Belgium / Q000453:epidemiology; D019468:Disease Management; D004196:Disease Outbreaks; D018562:Disease Transmission, Infectious / Q000706:statistics & numerical data; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000145:classification; D006482:Hemorrhagic Fevers, Viral / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission*; D006801:Humans; D007835:Lassa Fever / Q000175:diagnosis / Q000628:therapy / Q000635:transmission; D008379:Marburg Virus Disease / Q000175:diagnosis / Q000628:therapy / Q000635:transmission; D012307:Risk Factors