title: [Hemostasis disturbances in myocardial ischemia].
abstract: In this article, a description has been given of the close connection between coronary atherosclerosis and the onset of thrombosis. The hemostatic factors examined in this study are implicated both in the pathology of acute coronary syndromes and in the prognosis of ischemic heart disease. Amongst other factors, the role of the following has been investigated: platelets, thromboxane A2 and prostacyclin, von Willebrand factor, factor VII and tissue factor, thrombin, fibrinogen tissue plasminogen activator and plasminogen activator inhibitor. It is concluded that endothelial dysfunction in coronary atherosclerosis is the most frequent cause of disturbances in hemostatic function.
authors.affiliation: Service de cardiologie, centre hospitalier Sud-Francilien, hôpital Gilles-de-Corbeil, 59, boulevard Henri-Dunant, 91106 Corbeil Essonnes, France.
authors.forename: M
authors.initials: M
authors.lastname: Habis
authors.forename: C
authors.initials: C
authors.lastname: Gonzalez
authors.forename: L
authors.initials: L
authors.lastname: Jacq
authors.forename: M
authors.initials: M
authors.lastname: Pezzano
authors.forename: F
authors.initials: F
authors.lastname: Schaison
authors.forename: H
authors.initials: H
authors.lastname: Lardoux
mesh_terms: D001779:Blood Coagulation Factors / Q000502:physiology; D001792:Blood Platelets / Q000502:physiology; D006487:Hemostasis; D006801:Humans; D017202:Myocardial Ischemia / Q000097:blood* / Q000503:physiopathology*
chemical_list: D001779:Blood Coagulation Factors