title: Partial splenectomy in cystic fibrosis patients with hypersplenism.
abstract: We report three cystic fibrosis (CF) patients with hypersplenism who underwent partial splenectomy. The postoperative course was uneventful in two patients; one patient developed a complication necessitating resection of the rest of the spleen. Haematological parameters improved and oesophageal varices regressed in all patients. On follow up, one patient showed a normal spleen, the other a normally functioning accessory spleen; the third patient again developed splenomegaly with hypersplenism. Partial splenectomy is a promising therapeutic option for CF patients with hypersplenism.
authors.affiliation: Respiratory and Allergic Disease Division, Paediatric Department, University of Graz, Austria.
authors.forename: G H
authors.initials: GH
authors.lastname: Thalhammer
authors.forename: E
authors.initials: E
authors.lastname: Eber
authors.forename: S
authors.initials: S
authors.lastname: Uranüs
authors.forename: J
authors.initials: J
authors.lastname: Pfeifer
authors.forename: M S
authors.initials: MS
authors.lastname: Zach
mesh_terms: D000293:Adolescent; D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D006971:Hypersplenism / Q000150:complications / Q000601:surgery*; D008297:Male; D013154:Spleen / Q000601:surgery; D013156:Splenectomy / Q000379:methods*