Pulmonary microcrystalline cellulose deposition from intravenous injection of oral medication in a patient receiving parenteral nutrition.
A 50-year-old man who had been dependent on home parenteral nutrition (HPN) for 24 years presented with shortness of breath. A computed tomography scan of the lungs revealed a diffuse micronodular parenchymal infiltrate. On bronchoscopy, a crystalloid material was identified. This organic material was determined to be consistent with codeine. The patient had been injecting codeine into his intravenous catheter.
Ott
Michael C
MC
Division of Pulmonary Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Khoor
Andras
A
Scolapio
James S
JS
Leventhal
Jack P
JP
D000701:Analgesics, Opioid / Q000008:administration & dosage*; D002482:Cellulose / Q000009:adverse effects*; D003061:Codeine / Q000008:administration & dosage*; D005079:Excipients / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous / Q000009:adverse effects; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010288:Parenteral Nutrition; D014057:Tomography, X-Ray Computed
D000701:Analgesics, Opioid; D005079:Excipients; D002482:Cellulose; C109691:microcrystalline cellulose; D003061:Codeine