"Connective tissue nevus" and a serendipitous S-100 discovery.
Although desmoplastic melanoma is classically described as an indurated nodule on the head of an elderly patient associated with the histologic changes of an atypical intraepidermal melanocytic lesion accompanied by abnormal dermal spindled cells and rounded lymphoid infiltrates, it is capable of presenting in a variety of clinical and pathologic guises. Herein, a case with unusual clinical and histologic attributes is reported, which was initially misdiagnosed as a connective tissue nevus.
Cesinaro
Anna M
AM
Department of Morphologic and Forensic Sciences, Section of Anatomic Pathology, University of Modena e Reggio Emilia, Italy. cesinaro.a@policlinico.mo.it
D000328:Adult; D003238:Connective Tissue / Q000473:pathology; D003951:Diagnostic Errors; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008545:Melanoma / Q000737:chemistry / Q000175:diagnosis* / Q000601:surgery; D009506:Nevus / Q000737:chemistry / Q000175:diagnosis* / Q000601:surgery; D009418:S100 Proteins / Q000032:analysis*; D012878:Skin Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000601:surgery
D009418:S100 Proteins