[Compare of distributions of gene polymorphisms about alcohol metabolizing-related enzymes in five Chinese nationalities].
Genotypes of alcohol dehydrogenase 2(ADH2) and aldehyde dehydrogenase 2(ALDH2) were detected by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in order to acquire and compare the distributions of polymorphisms about ADH2 and ALDH2 in five Chinese nationalities. The results were as follows: (1) Heterozygous genotype of ADH2 and homozygous genotype of ALDH2 are the two dominant ones in all the five nationalities. (2) The distributions of the two genes 'polymorphisms have certain differences among some nationalities.
Cao
Xirong
X
School of Public Health, West China Medical Center of Sichuan University, Chengdu 610041, China.
Wu
Desheng
D
D000426:Alcohol Dehydrogenase / Q000235:genetics*; D000444:Aldehyde Dehydrogenase / Q000235:genetics*; D002681:China / Q000208:ethnology; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length
D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase