The advantages of using a modified microbatch method for rapid screening of protein crystallization conditions.
In this study, characterization and optimization of a modified microbatch crystallization technique has been attempted in order to provide a rapid screening method. Using this method for screening has certain advantages over standard vapour-diffusion methods: no sealing of drops is required, no reservoir solutions are needed and the experiments can easily be performed over a range of temperatures.
D'Arcy
Allan
A
Morphochem AG Basel, Switzerland. allan.darcy@morphochem.ch
Mac Sweeney
Aengus
A
Stihle
Martine
M
Haber
Alexander
A
D003460:Crystallization / Q000379:methods*; D018360:Crystallography, X-Ray; D004798:Enzymes / Q000737:chemistry*; D010232:Paraffin / Q000737:chemistry; D012827:Silicone Oils / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
D004798:Enzymes; D012827:Silicone Oils; D010232:Paraffin