Synthesis of highly substituted cyclopentenones via the [4 + 1] cycloaddition of nucleophilic carbenes and vinyl ketenes.
[reaction: see text] Vinyl ketenes have been shown to undergo [4 + 1] cycloaddition with a variety of nucleophilic carbenes to deliver highly substituted cyclopentenones as products.
Rigby
James H
JH
Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489, USA. jhr@chem.wayne.edu
Wang
Zhengqiang
Z