title: Treatment recommendations for the use of antipsychotics for aggressive youth (TRAAY). Part II.
abstract: OBJECTIVE
  To develop treatment recommendations for the use of antipsychotic medications for children and adolescents with serious psychiatric disorders and externalizing behavior problems.
  
  
  METHODS
  Using a combination of evidence- and consensus-based methodologies, recommendations were developed in six phases as informed by three primary sources of information: (1) current scientific evidence (published and unpublished), (2) the expressed needs for treatment-relevant information and guidance specified by clinicians in a series of focus groups, and (3) consensus of clinical and research experts derived from a formal survey and a consensus workshop.
  
  
  RESULTS
  Fourteen treatment recommendations on the use of atypical antipsychotics for aggression in youth with comorbid psychiatric conditions were developed. Each recommendation corresponds to one of the phases of care (evaluation, treatment, stabilization, and maintenance) and includes a brief clinical rationale that draws upon the available scientific evidence and consensus expert opinion derived from survey data and a consensus workshop.
  
  
  CONCLUSIONS
  Until additional research from controlled trials becomes available, these evidence- and consensus-based treatment recommendations may be a useful approach to guide the use of antipsychotics in youth with aggression.
authors.affiliation: Columbia University, New York, NY, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Pappadopulos
authors.forename: James C
authors.initials: JC
authors.lastname: Macintyre Ii
authors.forename: M Lynn
authors.initials: ML
authors.lastname: Crismon
authors.forename: Robert L
authors.initials: RL
authors.lastname: Findling
authors.forename: Richard P
authors.initials: RP
authors.lastname: Malone
authors.forename: Albert
authors.initials: A
authors.lastname: Derivan
authors.forename: Nina
authors.initials: N
authors.lastname: Schooler
authors.forename: Lin
authors.initials: L
authors.lastname: Sikich
authors.forename: Laurence
authors.initials: L
authors.lastname: Greenhill
authors.forename: Sarah B
authors.initials: SB
authors.lastname: Schur
authors.forename: Chip J
authors.initials: CJ
authors.lastname: Felton
authors.forename: Harvey
authors.initials: H
authors.lastname: Kranzler
authors.forename: David M
authors.initials: DM
authors.lastname: Rube
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Sverd
authors.forename: Molly
authors.initials: M
authors.lastname: Finnerty
authors.forename: Scott
authors.initials: S
authors.lastname: Ketner
authors.forename: Sonja E
authors.initials: SE
authors.lastname: Siennick
authors.forename: Peter S
authors.initials: PS
authors.lastname: Jensen
mesh_terms: D000293:Adolescent; D000374:Aggression / Q000523:psychology*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D017408:Guidelines as Topic; D006801:Humans; D011618:Psychotic Disorders / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents