[The curative effect of livostin spray on treating allergic rhinitis of children].
OBJECTIVE
To observe the effect of Livostin spray on children's allergic rhinitis and to search the mechanism of treating allergic rhinitis.


METHODS
113 patients were treated with Livostin spray (Livostin group) or normal saline spray (control group).


RESULTS
The total efficiency of Livostin group in treating allergic rhinitis is above 95.1% and that of the control group is 25.0%. Initial time of starting effect of Livostin (72.1%) is in 1 minute, and that of the control group (mostly 23.1%) is in 3 minutes. The keeping curative effect time of Livostin spray is mostly (72.1%) above 5 hours and that of the control group is mostly (30.8%) in 3 hours. After 2 weeks, the eosinophilic granulocyte number in nose's secretion of Livostin group is obviously reduced (P < 0.05).


CONCLUSIONS
Livostin is better than control group in relieving symptoms, keeping curative effect and safety, so Livostin is one kind of effective drug in treating children's allergic rhinitis.
Wang
S
S
Department of Otolaryngology, Children's Hospital, Wuhan 430016.
Xu
Z
Z
Xu
R
R
Wang
Z
Z
Rao
K
K
D000281:Administration, Intranasal; D000293:Adolescent; D000336:Aerosols; D002648:Child; D002675:Child, Preschool; D005260:Female; D006634:Histamine H1 Antagonists / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010880:Piperidines / Q000008:administration & dosage*; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*
D000336:Aerosols; D006634:Histamine H1 Antagonists; D010880:Piperidines; C047340:levocabastine