[The infiltration and activation stage of eosinophils in nasal polyps].
OBJECTIVE
To assess the infiltration and activation of eosinophils in nasal polyps.


METHODS
Nasal polyps from sixteen patients were investigated. The samples were stained with Chromotrope 2R histochemical and ABC immunohistochemical methods.


RESULTS
The majority of eosinophils in nasal polyps were activated, and there were no significant differences in the numbers of total eosinophils (Chromotrope 2R positive cells) and activated eosinophils (EG2 positive cells) between allergic and nonallergic patients.


CONCLUSIONS
Eosinophilia is a prominent histologic feature of nasal polyps which indicates that the activated eosinophils may play vital role in the pathogenesis of nasal polyps.
Zhang
L
L
Department of Otolaryngology-Head and Neck Surgery, Affiliated Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730.
Han
D
D
Zhang
Y
Y
Zhou
B
B
D000328:Adult; D004802:Eosinophilia / Q000473:pathology*; D004804:Eosinophils / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000473:pathology*