title: The development of a six-item daily self-report measure assessing identified depressive domains.
abstract: BACKGROUND
  There is debate as to whether any anti-depressant strategy acts more rapidly than any other, while 'improvement' in overall depression severity reflects a summation of individual domains that may individually show differing trajectories. We developed a brief self-report measure of depression's constituent constructs to allow such issues to be examined.
  
  
  METHODS
  A 25-item measure was prepared and completed daily by depressed patients until they had evidenced distinct improvement.
  
  
  RESULTS
  Factor analyses favoured a six-factor structure, with constructs labelled depression, irritability, brooding, poor concentration, insomnia and anxiety. Scores on those constructs were differentially associated with overall depression severity as measured on the clinician-rated Hamilton measure, arguing for their potential utility.
  
  
  CONCLUSIONS
  The original data set was small while the measure's utility will only emerge in application studies.
  
  
  CONCLUSIONS
  The six-item measure is appended and several possible application studies noted. In particular, we favour its evaluation in studies examining the impact and time to onset of differing antidepressant strategies on differing depressive sub-types.
authors.affiliation: Mood Disorders Unit, Prince of Wales Hospital, and School of Psychiatry, University of New South Wales, Sydney, Australia.
authors.forename: Gordon
authors.initials: G
authors.lastname: Parker
authors.forename: Kay
authors.initials: K
authors.lastname: Roy
mesh_terms: D000339:Affect / Q000187:drug effects*; D000704:Analysis of Variance; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003863:Depression / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D005163:Factor Analysis, Statistical; D006801:Humans; D010555:Personality Inventory / Q000706:statistics & numerical data*; D011594:Psychometrics; D012008:Recurrence; D015203:Reproducibility of Results; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents