[Determination of lidocaine in human spinal cord by high-performance liquid chromatography].
A RPHPLC method for determining lidocaine in human's spinal cord. Was established. The linear range of the method was 0.20-20.0 micrograms/ml(r = 0.9999). The detection limit was 0.02 ng/ml(S/N > or = 3) and the clean-up recovery of lidocaine in human spinal cord was 82.4%-92.7%. The CV% were no more than 6.0% (N = 4). No interfere by other compounds was observed in study results using this method. RPHPLC method shows an excellent recovery, high sensitivity and good precision.
Jing
M
M
Faculty of Forensic Medicine, Tongji Medical University, Wuhan 430030, PRC.
Wu
G
G
Yang
D
D
D000767:Anesthesia, Epidural; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005554:Forensic Medicine; D006801:Humans; D008012:Lidocaine / Q000032:analysis*; D012044:Regression Analysis; D012680:Sensitivity and Specificity; D013116:Spinal Cord / Q000737:chemistry*
D008012:Lidocaine