[Positive photobiological investigation in Jessner's lymphocytic infiltration of the skin].
BACKGROUND
Jessner's lymphocytic infiltration of the skin is a rare and benign disorder. Its clinical course is cyclic with remissions and exacerbations. In this disease, photosensitivity was previously noticed by authors and recently demonstrated. We report four new cases with positive photobiological investigation.


METHODS
Four patients (2 males, 2 females), with a mean age 36 years were seen with erythematous papules or discoid plaques on face, arms and upper trunk. The onset of disease occurred after sun exposure in summer. Skin biopsies showed perivascular lymphocytic infiltration in the dermis. All patients relapsed cyclically with incomplete healing during winter. Photobiological investigation elicited skin lesions in a broad spectrum of UV: UVB (2 cases), UVA (1 case), UVA and UVB (1 case). In all patients treatment with oral antimalarials and external photoprotection was effective.


CONCLUSIONS
Our data suggest that photosensitivity history in patients with Jessner's lymphocytic infiltration of the skin should be searched for, and confirmed by provocative phototesting. This relevant event could guide the therapeutic strategy because antimalarials were effective for the Jessner's lymphocytic infiltration cases with photosensitivity.
Adamski
H
H
Service de Dermatologie, CHU Pontchaillou, Rennes.
Labrousse
A-L
AL
Sparsa
A
A
Leonard
F
F
Le Gall
F
F
Labrousse
F
F
Ollivier
I
I
Bonnetblanc
J-M
JM
Chevrant-Breton
J
J
Bedane
C
C
Bernard
P
P
D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D010787:Photosensitivity Disorders / Q000209:etiology*; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology*; D014466:Ultraviolet Rays / Q000009:adverse effects
D000962:Antimalarials