[Determination of fenfluramine in corpse using GC/NPD and GC/MS].
A method was described for the determination of fenfluramine by GC/MS in blood, urine, liver, lung, kidney and heart tissues. After liquid-liquid extraction of fenfluramine in the specimens obtained from autopsy, the samples were qualitatively identified by GC/MS, and quantitatively determined by GC/NPD. 4-phenyl butylamine was used as internal standard. The concentrations of fenfluramine in blood, urine and liver were 7.8 micrograms/ml, 64.2 micrograms/ml and 31.3 micrograms/g respectively. The findings of autopsy and the results of toxicological analysis were also discussed.
Sun
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Institute of Forensic Sciences, Ministry of Justice, Shanghai 200063, P. R. China.
D000328:Adult; D002849:Chromatography, Gas / Q000379:methods; D005277:Fenfluramine / Q000032:analysis* / Q000506:poisoning*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D007668:Kidney / Q000737:chemistry; D008099:Liver / Q000737:chemistry; D008168:Lung / Q000737:chemistry; D008297:Male; D011041:Poisoning / Q000378:metabolism / Q000473:pathology
D005277:Fenfluramine