[Cut-off level of glycosylated hemoglobin indicating the development of complications in type 2 diabetes mellitus].
Prevention of chronic complications is very important in the management of type 2 diabetes, and the availability of a laboratory test individuating at risk subjects should have a marked usefulness. This study sought by the method of ROC curves the cut-off of glycated haemoglobin discriminating the subjects with microvascular, neurologic and renal complications from those without. The cut-off was identified at a glycated haemoglobin level of 7.95, showing a sensitivity of 74.8% and a specificity of 73.3%, which makes it a possible tool for evaluating the risk of complications in type 2 diabetes.
Incorvaia
Cristoforo
C
Medicina Riabilitativa II, Istituti Clinici di Perfezionamento, Milano. cristoforo.incorvaia@fastwebnet.it
Maraffi
Franco
F
Megali
Raffaella
R
Nitti
Fabio
F
Fumagalli
Mario
M
D016001:Confidence Intervals; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D012372:ROC Curve; D012680:Sensitivity and Specificity
D006442:Glycated Hemoglobin