title: Notoginseny cream in the treatment of phlebitis.
abstract: This study investigated the curative effects of notoginseny cream versus Hirudoid cream in the treatment of postinfusion phlebitis. Sixty-five patients who received peripheral infusion therapy during a 20-month period and had developed phlebitis were divided randomly into two groups. Group A was treated with notoginseny cream, a topical Chinese medicine developed and produced by the pharmacological department of The Second Affiliated Hospital of Sun Yat-Sen University. Group B was treated with heparinoid cream (Hirudoid, a commercial product from Germany). Significantly fewer applications of notoginseny cream were required to bring about the disappearance of signs and symptoms of phlebitis in the group A patients as compared with the group B patients for the same effect. The actual time of disappearance of the signs and symptoms of phlebitis also were significantly shorter in patients treated with notoginseny cream than with heparinoid cream.
authors.affiliation: Department of Stomatology, The Second Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdon Province, People's Republic of China. jola105@hotmail.com
authors.forename: Zhang
authors.initials: Z
authors.lastname: Gouping
authors.forename: Tan
authors.initials: T
authors.lastname: Wan-Er
authors.forename: Weng
authors.initials: W
authors.lastname: Xue-Ling
authors.forename: Xian
authors.initials: X
authors.lastname: Min-Qian
authors.forename: Fang
authors.initials: F
authors.lastname: Kun
authors.forename: Sue
authors.initials: S
authors.lastname: Turale
authors.forename: John W
authors.initials: JW
authors.lastname: Fisher
mesh_terms: D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D031187:Carthamus tinctorius; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D036145:Ginsenosides / Q000627:therapeutic use*; D006496:Heparinoids / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009730:Nursing Assessment; D009824:Ointments; D010689:Phlebitis / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology*; D008517:Phytotherapy / Q000379:methods*; D012250:Rheum; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal; D036145:Ginsenosides; D006496:Heparinoids; D009824:Ointments; C542919:notoginseny; C046596:Hirudoid; C072936:notoginsenoside R1