title: Mucinous carcinoma of the skin with apocrine-type differentiation: immunohistochemical studies.
abstract: We investigated the pathway of differentiation in a case of mucinous carcinoma of the skin (MCS) arising on the right temple of a 70-year-old man. Histopathologic findings of the tumor showed evidence of apocrine-type differentiation such as distinctive decapitation secretion. Additionally, by employing a panel of antibodies, the immunohistochemical staining pattern of tumor cells was shown to be compatible with that of apocrine glands. Although the differentiation of this neoplasm remains controversial, the findings in our case suggest apocrine differentiation.
authors.affiliation: Department of Dermatology, Akita University School of Medicine, Hondo, Akita City, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Wako
authors.forename: Keiko
authors.initials: K
authors.lastname: Nishimaki
authors.forename: Nanami
authors.initials: N
authors.lastname: Kawamura
authors.forename: Natsuko
authors.initials: N
authors.lastname: Harima
authors.forename: Takashi
authors.initials: T
authors.lastname: Kubota
authors.forename: Kozo
authors.initials: K
authors.lastname: Yoneda
authors.forename: Motomu
authors.initials: M
authors.lastname: Manabe
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Ansai
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D000368:Aged; D001050:Apocrine Glands / Q000737:chemistry / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000737:chemistry / Q000473:pathology*; D005153:Facial Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery