Determination of benzene in urine by static headspace gas chromatography.
This paper describes the application of static headspace gas chromatography in determining benzene in urine. The method was analytically validated for sensitivity (DL = 42 ng/l), repeatability (RSD = 3% and 4%), and accuracy (71%), and was applied in measuring urine benzene in nonsmokers (N = 14) and smokers (N = 18). All urine samples had measurable benzene concentrations. The method proved sensitive enough to establish a significant statistical difference (P < 0.000614) in urine benzene concentrations between smokers (mean = 760; range = 181-1869 ng/l) and nonsmokers (mean = 214; range = 61-515 ng/l).
Skender
Ljiljana
L
Institute for Medical Research and Occupational Health, Zagreb, Croatia. Ljiljana.Skender@imi.hr
Brcić
Irena
I
Zuzul
Silva
S
D000328:Adult; D001554:Benzene / Q000032:analysis*; D002849:Chromatography, Gas / Q000379:methods; D004785:Environmental Pollutants / Q000652:urine*; D006801:Humans; D012680:Sensitivity and Specificity; D012907:Smoking / Q000652:urine; D016482:Urinalysis / Q000379:methods
D004785:Environmental Pollutants; D001554:Benzene