title: [The experimental research of the killing effect of energy-controllable steep pulse on tumor tissue in vitro].
abstract: Experimental research of injury on tumor tissue in vitro is conducted with homemade energy-controllable steep pulse device. With the comparison of histological assay results between treatment group and non-treatment group, basic phenomenon of electrochemical reaction and pathology reaction of tumor tissue during the experiment is observed. The results showed the irreversible breakdown penetrating effect of energy-controllable steep pulse on tumor cells and the feasibility of this therapy are also demonstrated. These results provide a consolidate theoretic and applicable basis for further study on mechanism and animal experiment in vivo.
authors.affiliation: College of Electrical Engineering, Chongqing University, Key Laboratory of High Voltage Engineering and Electrical New Technology, Ministry of Education, Chongqing 400044.
authors.forename: Lan
authors.initials: L
authors.lastname: Xiong
authors.forename: Caixin
authors.initials: C
authors.lastname: Sun
authors.forename: Daqiang
authors.initials: D
authors.lastname: Li
authors.forename: Ruijin
authors.initials: R
authors.lastname: Liao
authors.forename: Lina
authors.initials: L
authors.lastname: Hu
mesh_terms: D004599:Electric Stimulation Therapy / Q000295:instrumentation / Q000379:methods*; D004574:Electromagnetic Fields; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000473:pathology / Q000628:therapy*