[The clinical value of the TSGF pre and post-therapy in patients with nasopharyngeal carcinoma(NPC)].
OBJECTIVE
To investigate the role of TSGF (tumor supplied group of factor) in early diagnosing and predicting in patients with NPC.


METHODS
EBV-IgA and level of TSGF were measured before therapy and 1 month, 1 year after therapy in 35 patients with NPC, and the relationship between them was researched.


RESULTS
The diagnostic sensitivity of TSGF and EBV-IgA was 91%, 97% respectively, there is no significant relation between them. After treatment, the level of TSGF in PD (progression disease) patient remained higher, but had a significantly drop in RR(including the CR, PR and SI)) patient.


CONCLUSIONS
Results suggested that TSGF may be useful in diagnosing and prediction of NPC.
Zhang
H
H
Department of Oncology, Medical Centre of Zhuhai, Zhuhai 519000.
Le
J
J
Huang
X
X
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000097:blood* / Q000628:therapy; D011379:Prognosis
D014408:Biomarkers, Tumor; D007070:Immunoglobulin A