Novel clonal der(8)t(8;14)(p11;q11),del(9)(q13q22) and t(14;22) (q13;q13) in a patient with fulminant adult T-cell leukemia/lymphoma.
We describe a 70-year-old man with fulminant adult T-cell leukemia/lymphoma. He died of progressive disease 1 week after the onset of symptoms. The integrated viral DNA of human T-lymphotropic virus type I was detected in the bone marrow aspirate by polymerase chain reaction. Cytogenetic analysis of bone marrow cells showed novel clonal aberrations consisting of 46,XY,der(8)t(8;14)(p11;q11),del(9) (q13q22),t(14;22)(q13;q13).
Yeh
Su-Peng
SP
Division of Hematology and Oncology, Department of Internal Medicine, China Medical College Hospital, 2 Yuh Der Road, Taichung 404, Taiwan. superyeh@pavo.seed.net.tw
Yu
Ming-Tsong
MT
Chow
Kuan-Chih
KC
Lai
Ling-Ya
LY
Chiu
Chang-Fang
CF
D000368:Aged; D001483:Base Sequence; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002883:Chromosomes, Human, Pair 14; D002892:Chromosomes, Human, Pair 22; D002898:Chromosomes, Human, Pair 8; D002899:Chromosomes, Human, Pair 9; D017931:DNA Primers; D006801:Humans; D007621:Karyotyping; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000097:blood / Q000235:genetics* / Q000473:pathology*; D008297:Male; D014178:Translocation, Genetic
D017931:DNA Primers