title: Synthesis and insecticidal activity of novel dihydropyrrole derivatives with N-sulfanyl, sulfinyl, and sulfonyl moieties.
abstract: This paper reports the synthesis and insecticidal activity of a new type of dihydropyrrole derivatives with sulfur moieties such as sulfanyl, sulfinyl, and sulfonyl groups at the 1-position. These derivatives exhibited high insecticidal potency against Nilaparvata lugens and Nephotettix cincticeps. Investigation of the structure-activity relationships revealed that the alkoxycarbonyloxy groups at the 4-position tended to increase the systemic insecticidal activity.
authors.affiliation: Agroscience Research Laboratories, Sankyo Co., Ltd., 1041 Yasu, Yasu-cho, Yasu-gun, 520-2342, Shiga, Japan. mtitou@shina.sankyo.co.jp
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Ito
authors.forename: Hideshi
authors.initials: H
authors.lastname: Okui
authors.forename: Harumi
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Shigeru
authors.initials: S
authors.lastname: Mio
authors.forename: Ayako
authors.initials: A
authors.lastname: Kinoshita
authors.forename: Takashi
authors.initials: T
authors.lastname: Obayashi
authors.forename: Takako
authors.initials: T
authors.lastname: Miura
authors.forename: Junko
authors.initials: J
authors.lastname: Nagai
authors.forename: Shinji
authors.initials: S
authors.lastname: Yokoi
authors.forename: Reiji
authors.initials: R
authors.lastname: Ichinose
authors.forename: Keiji
authors.initials: K
authors.lastname: Tanaka
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Kodama
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Takaaki
authors.initials: T
authors.lastname: Miyake
authors.forename: Miho
authors.initials: M
authors.lastname: Takashio
authors.forename: Jun
authors.initials: J
authors.lastname: Iwabuchi
mesh_terms: D000818:Animals; D006430:Hemiptera; D007306:Insecticides / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D012275:Oryza / Q000187:drug effects; D011758:Pyrroles / Q000138:chemical synthesis* / Q000633:toxicity*; D013055:Spectrophotometry, Infrared; D013329:Structure-Activity Relationship; D013441:Sulfinic Acids / Q000737:chemistry*; D013451:Sulfonic Acids / Q000737:chemistry*
chemical_list: D007306:Insecticides; D011758:Pyrroles; D013441:Sulfinic Acids; D013451:Sulfonic Acids