Epidemiological modeling in a branching population. Particular case of a general SIS model with two age classes.
This paper covers the elaboration of a general class of multitype branching processes for modeling in a branching population, the evolution of a disease with horizontal and vertical transmissions. When the size of the population may tend to infinity, normalization must be carried out. As the initial size tends to infinity, the normalized model converges a.s. to a dynamical system the solution of which is the probability law of the state of health for an individual ancestors line. The focal point of this study concerns the transient and asymptotical behaviors of a SIS model with two age classes in a branching population. We will compare the asymptotical probability of extinction on the scale of a finite population and on the scale of an individual in an infinite population: when the rates of transmission are small compared to the rate of renewing the population of susceptibles, the two models lead to a.s. extinction, giving consistent results, which no longer applies to the opposite situation of important transmissions. In that case the size of the population plays a crucial role in the spreading of the disease.
Jacob
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INRA, Unité de Biométrie, 78352 Jouy-en-Josas Cedex, France. cj@jouy.inra.fr
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D000367:Age Factors; D003141:Communicable Diseases / Q000453:epidemiology*; D018562:Disease Transmission, Infectious; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008954:Models, Biological; D011157:Population Dynamics