[An experimental study on the change of adhesion between leukocyte and endothelium in acute cerebral ischemia].
The objective of this experiment was to investigate the change of leukocyte adhesion in the focus of cerebral ischemia-reperfusion injury. Immune fluorescent microscope equipped with image tube camera and high speed recording TV sets was used to study the leukocyte adhesion in the focus of cerebral ischemia-reperfusion injury. The result showed that the density index of adherent leukocyte was significantly elevated, the fracture stress between leukocyte and endothelium dropped, and the adhesion increased in the focus of cerebral ischmic-reperfusion injury. These findings indicated that leukocyte adhesion was increased significantly and leukocytes played an important role in the cerebral ischemia-reperfusion injury.
Zhou
H
H
Department of Daping Hospital, Third Military Medical University, Chongqing 400042.
Li
Z
Z
Li
J
J
Chen
M
M
D000208:Acute Disease; D000818:Animals; D002545:Brain Ischemia / Q000503:physiopathology*; D002448:Cell Adhesion; D004730:Endothelium, Vascular / Q000166:cytology / Q000503:physiopathology*; D007962:Leukocytes / Q000502:physiology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D015427:Reperfusion Injury / Q000503:physiopathology*