title: Different effects of phencyclidine and methamphetamine on firing activity of medial prefrontal cortex neurons in freely moving rats.
abstract: The purpose of this study was to compare the effects of systemically administered MAP with those of phencyclidine (PCP), both of which induced comparable locomotor activity, on firing activity of medial prefrontal cortex (mPFC) neurons in freely moving rats. The results show that, unlike PCP, acutely administered MAP produced little changes in firing activity of mPFC neurons.
authors.affiliation: Department of Physiology, Fukushima Medical University School of Medicine, 1 Hikari-ga-oka, Fukushima 960-1295, Japan. jodo1019@fmu.ac.jp
authors.forename: Eiichi
authors.initials: E
authors.lastname: Jodo
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takeuchi
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Niwa
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Kayama
mesh_terms: D000818:Animals; D005071:Evoked Potentials / Q000187:drug effects*; D007274:Injections, Intraperitoneal; D008297:Male; D008694:Methamphetamine / Q000008:administration & dosage / Q000494:pharmacology*; D008839:Microelectrodes; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D010622:Phencyclidine / Q000008:administration & dosage / Q000494:pharmacology*; D017397:Prefrontal Cortex / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D011930:Reaction Time / Q000187:drug effects
chemical_list: D008694:Methamphetamine; D010622:Phencyclidine