Synthesis and insecticidal activity of novel N-oxydihydropyrroles: 4-hydroxy-3-mesityl-1-methoxymethoxy derivatives with various substituents at the 5-position.
This paper reports the synthesis and insecticidal activity of a series of novel 4-hydroxy-3-mesityl-1-methoxymethoxy-1,5-dihydro-2H-pyrrol-2-one derivatives, in which the substituents at the 5-position were varied with a number of alkyl and spirocycloalkyl groups. Investigation of the structure-activity relationships revealed that small alkyl and spirocyclohexyl groups had a favorable effect on the insecticidal activity of these agents against Myzus persicae.
Ito
Mitsuru
M
Agroscience Research Laboratories, Sankyo Co., Ltd., 1041 Yasu, Yasu-cho, Yasu-gun, Shiga 520-2342, Japan. mtitou@shina.sankyo.co.jp
Okui
Hideshi
H
Nakagawa
Harumi
H
Mio
Shigeru
S
Kinoshita
Ayako
A
Obayashi
Takashi
T
Miura
Takako
T
Nagai
Junko
J
Yokoi
Shinji
S
Ichinose
Reiji
R
Tanaka
Keiji
K
Kodama
Seiichiro
S
Iwasaki
Toshiaki
T
Miyake
Takaaki
T
Takashio
Miho
M
Iwabuchi
Jun
J
D000818:Animals; D001042:Aphids; D001937:Brassica; D018553:Cucumis sativus; D006540:Herbicides / Q000633:toxicity; D007202:Indicators and Reagents; D007306:Insecticides / Q000138:chemical synthesis* / Q000633:toxicity*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000633:toxicity*; D013329:Structure-Activity Relationship
D006540:Herbicides; D007202:Indicators and Reagents; D007306:Insecticides; D011758:Pyrroles