[Surface phenotype on dendritic cells and their immunological significance].
Dendritic cells (DC) are very important antigen presenting cells(APC) in immune response. DC gradually gets mature while it migrates in vivo. Compared with mature DC, immature DC plays a different role in immune response. In this review, the recent advances in researches on specific cell surface marker and costimulatory molecules on DC as well as their immunological significance and methodology of propagation in vitro are discussed. It may be beneficial for further study of DC.
Chen
Y
Y
Transplantation Immunology Laboratory, First Hospital, West China University of Medical Sciences, Chengdu 610041.
Bu
H
H
Li
Y
Y
D015703:Antigens, CD / Q000096:biosynthesis; D051940:B7-2 Antigen; D019013:CD40 Antigens / Q000096:biosynthesis; D002455:Cell Division; D002478:Cells, Cultured; D003713:Dendritic Cells / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D016130:Immunophenotyping; D008562:Membrane Glycoproteins / Q000096:biosynthesis / Q000276:immunology; D000097802:CD83 Antigen
D015703:Antigens, CD; D051940:B7-2 Antigen; D019013:CD40 Antigens; D007136:Immunoglobulins; D008562:Membrane Glycoproteins; D000097802:CD83 Antigen; C497964:CD86 protein, human