title: [Cytomegalovirus cellulitis].
abstract: Cutaneous lesions in CMV infection are rare, often a late manifestation of systemic infection, and usually herald a fatal course. A 70 year-old woman received a kidney transplantation one month before consulting and immunosuppressive therapy that included cyclosporine A and methylprednisone. She complained of fever, local pain in her right leg, and an erythematous and swelling plaque. She was treated with intravenous antibiotics without improvement. A skin biopsy was performed and the tissue obtained was sent for bacterial and fungal cultures as well as for histological examination. Cultures were negative. The biopsy showed CMV cytopathic changes. Immunoperoxidase staining was positive for CMV and polymerase chain reaction (PCR) testing revealed CMV DNA. She was treated with ganciclovir with resolution of the lesion. CMV cellulitis is a rare cutaneous manifestation which has not been previously reported.
authors.affiliation: Servicio Dermatología, Hospital Privado de Córdoba, Córdoba, Argentina.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Ruiz Lascano
authors.forename: Raquel
authors.initials: R
authors.lastname: Kuznitzky
authors.forename: Iliana
authors.initials: I
authors.lastname: Garay
authors.forename: María
authors.initials: M
authors.lastname: Kurpis
authors.forename: Pablo
authors.initials: P
authors.lastname: Massari
mesh_terms: D000368:Aged; D002481:Cellulitis / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000009:adverse effects / Q000276:immunology