title: A mild deprotection strategy for allyl-protecting groups and its implications in sequence specific dendrimer synthesis.
abstract: A mild deprotection strategy for allyl ethers under basic conditions in the presence of a palladium catalyst is described. Under these conditions, aryl allyl ethers can be cleaved selectively in the presence of alkyl allyl ethers. These conditions are also effective in the deprotection of allyloxycarbonyl groups. The utility of the current methodology in sequence specific dendrimer synthesis is demonstrated.
authors.affiliation: Department of Chemistry, Tulane University, New Orleans, Louisiana 70118, USA.
authors.forename: Dharma Rao
authors.initials: DR
authors.lastname: Vutukuri
authors.forename: Pandi
authors.initials: P
authors.lastname: Bharathi
authors.forename: Zhouying
authors.initials: Z
authors.lastname: Yu
authors.forename: Karthik
authors.initials: K
authors.lastname: Rajasekaran
authors.forename: My-Huyen
authors.initials: MH
authors.lastname: Tran
authors.forename: S
authors.initials: S
authors.lastname: Thayumanavan
mesh_terms: D000498:Allyl Compounds / Q000737:chemistry*; D001592:Benzyl Alcohols / Q000138:chemical synthesis*; D002384:Catalysis; D004987:Ethers / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: C475740:3-(4-tert-butylbenzyloxy)-5-(3-methylbenzyloxy)-benzyl alcohol; D000498:Allyl Compounds; D001592:Benzyl Alcohols; D004987:Ethers; D007202:Indicators and Reagents; D010165:Palladium