title: [Study of effects of six caries-preventive agents on enamel decalcification].
abstract: OBJECTIVE
  To compare the influence of 6 caries-preventive agents containing fluoride and trace element on dental enamel decalcification and observe the relationship between enamel decalcification and time of early carious lesions.
  
  
  METHODS
  84 bovine teeth were selected and divided into 7 groups. Experimental groups were treated with SrF, SnF2, (NH4)2 MoO2F4, ZnF, LaF and NaF with the same [F-]concentration and deionised water respectively, then all the specimens formed artificial carious lesion in lactic acid gel.
  
  
  RESULTS
  The [Ca2+] concentration of lactic acid gel showed a variety of enamel decalcification among specimens treated with fluoride agents after 48 hours, on the other hand, all the specimens presented a platform of enamel decalcification after 48 hours. SnF2 demonstrated the strongest inhibition on enamel decalcification, meanwhile, NaF has the minimum influence on it.
  
  
  CONCLUSIONS
  The time of forming artificial carious lesion with acid etch is about 48 hours, moreover, caries-preventive agents containing fluoride and trace element are effectively able to inhibit enamel decalcification, and the potential mechanism is the interaction of fluoride and trace element.
authors.affiliation: College of Stomatology, West China University of Medical Sciences.
authors.forename: H
authors.initials: H
authors.lastname: Wu
authors.forename: X
authors.initials: X
authors.lastname: Zhou
authors.forename: P
authors.initials: P
authors.lastname: Zhang
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: W
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000818:Animals; D002417:Cattle; D003731:Dental Caries / Q000517:prevention & control; D003743:Dental Enamel / Q000187:drug effects*; D005460:Fluorides, Topical / Q000494:pharmacology*; D066298:In Vitro Techniques; D017001:Tooth Demineralization / Q000517:prevention & control*; D014131:Trace Elements / Q000494:pharmacology
chemical_list: D005460:Fluorides, Topical; D014131:Trace Elements