[Cell infiltration in nasal polyps and it's pathological significance].
OBJECTIVE
To study the relation between inflammatory cells infiltration in nasal polyp tissues and it's pathogenesis.


METHODS
Nasal mucosa from 10 normal individual and 4 patients of nasal polyps were studied with immunohistochemical technique and histopathologic examination.


RESULTS
The number of eosinophils, CD68 positive cells and monocytes was significantly higher (P < 0.05) in nasal polyps tissues than in the normal controls.


CONCLUSIONS
Infiltration of inflammatory effector cells such as eosinphils and chronic inflammatory changes of the nasal mucosa might play a role in nasal polyps sprouting.
Kong
H
H
Department of Otolaryngology, Head and Neck Surgery, Third Clinical College, Norman Bethune University of Medical Sciences, Changchun 130031.
Yang
J
J
Dong
Z
Z
Yang
Z
Z
Pu
G
G
D015703:Antigens, CD / Q000096:biosynthesis; D015214:Antigens, Differentiation, Myelomonocytic / Q000096:biosynthesis; D004804:Eosinophils / Q000473:pathology*; D006801:Humans; D008264:Macrophages / Q000378:metabolism / Q000473:pathology*; D009000:Monocytes / Q000378:metabolism / Q000473:pathology; D009298:Nasal Polyps / Q000473:pathology*; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; C067980:CD68 antigen, human; D000097382:CD68 Molecule