title: Liver resection for hepatic metastases: 15 years of experience.
abstract: OBJECTIVE
  Liver metastases, especially those from primary colorectal cancers, are treatable and potentially curable. Imaging techniques such as computed tomography, magnetic resonance, and ultrasonography have advanced in recent years and led to increased sensitivity and specificity in the diagnosis of liver metastases. Liver surgery also has been revolutionized in the past two decades. Dissection along nonanatomical lines has permitted the resection of multiple lesions that previously might have been considered unresectable.
  
  
  METHODS
  From 1986 to 2000, 181 patients underwent liver resection for hepatic metastasis from colorectal cancer. Of these, 56 patients underwent systematic anatomical major hepatic resection and 125 underwent nonanatomical limited resection.
  
  
  RESULTS
  Operative morbidity and mortality rates were higher in patients in whom anatomical procedures were performed. The overall 5-year survival rate of the 181 patients was 39.8%.
  
  
  CONCLUSIONS
  An aggressive surgical procedure in patients with hepatic colorectal metastases is safe, and may prolong overall survival, and therefore should be considered in all patients with metastases confined to the liver.
authors.affiliation: Department of General and Hepato-Pancreato-Biliary Surgery, S. Maria di Loreto nuovo Hospital, Naples, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Belli
authors.forename: Alberto
authors.initials: A
authors.lastname: D'Agostino
authors.forename: Fabio
authors.initials: F
authors.lastname: Ciciliano
authors.forename: Corrado
authors.initials: C
authors.lastname: Fantini
authors.forename: Nadia
authors.initials: N
authors.lastname: Russolillo
authors.forename: Andrea
authors.initials: A
authors.lastname: Belli
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate