Thymic epithelial hyperplasia with nodular sclerosis Hodgkin's disease.
We report a case of simultaneous occurrence of thymic epithelial hyperplasia and Hodgkin's disease. A computed tomographic scan of the chest revealed a tumor in the anterior mediastinum and conspicuous swelling of lymph nodes in the upper and lower mediastinum. The anterior mediastinal tumor was histologically diagnosed as thymic epithelial hyperplasia, while the lymph nodes were nodular sclerosis Hodgkin's disease. Our findings suggest that thymic hyperplasia might be directly involved in the pathology of at least some cases of Hodgkin's disease.
Ito
Wataru
W
Second Department of Medicine, Okayama University Medical School, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Kojima
Kensuke
K
Fujiwara
Kumi
K
Nanba
Yasuo
Y
Yoshino
Tadashi
T
Shinagawa
Katsuji
K
Ishimaru
Fumihiko
F
Ikeda
Kazuma
K
Niiya
Kenji
K
Tanimoto
Mitsune
M
D000328:Adult; D004847:Epithelial Cells / Q000473:pathology; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000473:pathology*; D016539:Reed-Sternberg Cells; D012074:Remission Induction; D012598:Sclerosis; D013952:Thymus Hyperplasia / Q000473:pathology*; D014057:Tomography, X-Ray Computed