Cognitive deficits in patients with hepatic cirrhosis and in liver transplant recipients.
This study assessed cognitive deficit in patients diagnosed with different stages of hepatic cirrhosis and in liver transplant recipients. A short protocol consisting of several psychometric tests was used. Cirrhotic patients showed a degree of mental impairment in all the functions studied. The severity of the deficit was related to the degree of hepatic dysfunction. In contrast, liver transplant recipients presented only a slightly altered cerebral dysfunction in comparison to the control group. Their cognitive capacity was slightly better than that of patients with asymptomatic cirrhosis.
Pantiga
Carmen
C
Psychobiology Laboratory, Department of Psychiatry, University of Oviedo, Spain.
Rodrigo
Luis R
LR
Cuesta
Marcelino
M
Lopez
Laudino
L
Arias
Jorge L
JL
D000328:Adult; D000368:Aged; D003072:Cognition Disorders / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006501:Hepatic Encephalopathy / Q000175:diagnosis* / Q000523:psychology; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000523:psychology; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000175:diagnosis* / Q000523:psychology; D011594:Psychometrics