title: Efficacy of cobalt-60 radiation therapy for the treatment of nasal cavity nonkeratinizing squamous cell carcinoma in the dog.
abstract: The purposes of this study were to evaluate the efficacy of cobalt-60 radiotherapy in the treatment of nonkeratinizing squamous cell carcinoma of the nasal cavity in dogs and to compare this treatment group to historical controls. Six dogs with histopathologically confirmed nasal cavity nonkeratinizing squamous cell carcinoma were treated with cobalt-60 radiotherapy to a total dose of either 63 Gy or 54 Gy. Overall survival times ranged from 30 days to 330 days, with a median survival time of 165 days. Nasal cavity nonkeratinizing squamous cell carcinoma in the dog is an aggressive tumor that responds poorly to radiotherapy.
authors.affiliation: Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, South Stadium Drive, Baton Rouge, Louisiana 70803, USA.
authors.forename: Stephanie Shank
authors.initials: SS
authors.lastname: Correa
authors.forename: G Neal
authors.initials: GN
authors.lastname: Mauldin
authors.forename: Glenna E
authors.initials: GE
authors.lastname: Mauldin
authors.forename: Amiya K
authors.initials: AK
authors.lastname: Patnaik
mesh_terms: D000818:Animals; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000662:veterinary*; D003037:Cobalt Radioisotopes / Q000008:administration & dosage*; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000401:mortality / Q000532:radiotherapy*; D004285:Dogs; D008145:Louisiana; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000532:radiotherapy / Q000662:veterinary*; D011859:Radiography; D011879:Radiotherapy Dosage / Q000662:veterinary; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D003037:Cobalt Radioisotopes