title: Are antidepressants effective in fibromyalgia?
abstract: Amitriptyline and other imipramine antidepressants are the cornerstone of drug therapy in fibromyalgia. However, some patients fail to respond to antidepressant therapy, and in responders the beneficial effects wear off after some time. The effect on fibromyalgia seems independent from the effects on depression.
authors.forename: Eric
authors.initials: E
authors.lastname: Thomas
authors.forename: Francis
authors.initials: F
authors.lastname: Blotman
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003863:Depression / Q000150:complications / Q000188:drug therapy; D005356:Fibromyalgia / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents