Acetylene sesquiterpenoid esters from the green alga Caulerpa prolifera.
Sixteen secondary metabolites of the green alga Caulerpa prolifera have been isolated, and their chemical structures elucidated by analysis of their spectroscopic data. Two groups of metabolites have been established, with either a 1,2-dihydro- (2a-2i) or a 1,2,3,3'-tetrahydro-2,3-didehydro (3a-3f) caulerpenyne carbon backbone. The terminal vinyl acetoxy group of caulerpenyne was substituted by various fatty acid residues. The antifouling activity of the algal extract was tested in laboratory assays against two of the major groups of fouling organisms (bacteria, microalgae).
Smyrniotopoulos
Vangelis
V
School of Pharmacy, Department of Pharmacognosy and Chemistry of Natural Products, University of Athens, Panepistimioupolis Zografou, 157 71 Athens, Greece.
Abatis
Dennis
D
Tziveleka
Leto-A
LA
Tsitsimpikou
Christina
C
Roussis
Vassilios
V
Loukis
Anargyros
A
Vagias
Constantinos
C
D000114:Acetylene / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002734:Chlorophyll / Q000032:analysis; D000460:Chlorophyta / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D017753:Ecosystem; D004952:Esters / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006115:Greece; D006131:Growth Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013058:Mass Spectrometry; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D004952:Esters; D006131:Growth Inhibitors; D012717:Sesquiterpenes; D002734:Chlorophyll; C097889:caulerpenyne; D000114:Acetylene