title: [Growth of Methylomonas Z201 cells and production of epoxypropane in monophasic and biphasic fermentation systems].
abstract: The growth of Methylomonas Z201 cells and production of epoxypropane in mono- and biphasic fermentation systems were studied. In monophasic fermentation systems, the inhibitions of propene and epoxypropane on the growth of Methylomonas Z201 cells were observed and the concentration of epoxypropane reached 1.3 mmol/L. In biphasic fermentation systems, hexadecane acted as the "reservoir" of growth substrate (methane) and reactants (propene, molecular oxygen), the decrease of propene and epoxypropane in aqueous phase reduced the inhibition effect of propene and epoxypropane on the growth of cells, the concentrations of epoxypropane in both water phase and hexadecane phase reached 1.7 mmol/L and 2.6 mmol/L. In both monophasic and biphasic fermentation systems, the operational stability of cells was enhanced compared to that of resting cells.
authors.affiliation: State Key Laboratory of Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000.
authors.forename: S
authors.initials: S
authors.lastname: Xia
authors.forename: C
authors.initials: C
authors.lastname: Yu
authors.forename: S
authors.initials: S
authors.lastname: Li
mesh_terms: D000475:Alkenes / Q000494:pharmacology; D002478:Cells, Cultured; D004852:Epoxy Compounds / Q000378:metabolism*; D005285:Fermentation; D008697:Methane / Q000494:pharmacology; D008772:Methylococcaceae / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D011407:Propane / Q000378:metabolism*
chemical_list: D000475:Alkenes; D004852:Epoxy Compounds; C013658:propylene; D008697:Methane; D011407:Propane