title: [Cutaneous complications in idiopathic inflammatory bowel disease].
abstract: A 29-year-old male patient with the anamnesis of inflammatory bowel disease and Grave-Basedowov disease was hospitalized because of rapidly spreading skin defect with affected muscle on the left shin. This skin defect appeared after the significant decreasing of corticoids. The small skin trauma preceded the pyoderma gangrenosum. First the skin disease was not right diagnosed and patient was cured by the excision of the defect. It caused tissue disintegration, muscle necrosis and extension of the defect. The whole leg was endangered. Patient was cured with corticoids and cyclosporin A after the right diagnosis. The defect healed and laboratory inflammatory markers decreased. The immunosuppresive therapy was changed to azathioprin, the corticoid therapy was interrupted. After three months the defect was healed.
authors.affiliation: Gastroenterologické centrum IV. interní kliniky 1. LF UK a VFN, Praha. p.chalupna@seznam.cz
authors.forename: P
authors.initials: P
authors.lastname: Chalupná
authors.forename: M
authors.initials: M
authors.lastname: Lukás
authors.forename: S
authors.initials: S
authors.lastname: Adamec
authors.forename: R
authors.initials: R
authors.lastname: Sroubková
authors.forename: M
authors.initials: M
authors.lastname: Antosová
authors.forename: S
authors.initials: S
authors.lastname: Romaniv
mesh_terms: D000328:Adult; D003093:Colitis, Ulcerative / Q000150:complications*; D006111:Graves Disease / Q000150:complications; D006801:Humans; D007871:Leg Ulcer / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008297:Male; D017511:Pyoderma Gangrenosum / Q000150:complications* / Q000175:diagnosis / Q000628:therapy