title: Hydroxyalkylation of alpha-C-H bonds of tetrahydrofuran with aldehydes in the presence of triethylborane and tert-butyl hydroperoxide.
abstract: The alpha-hydroxyalkylation of tetrahydrofuran with aldehydes via radical C-H abstraction was conducted using triethylborane in the presence of tert-butyl hydroperoxide. This study presents a rare instance of direct intermolecular radical addition of unactivated cyclic ether to aldehydes.
authors.affiliation: Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan. takey@my-pharm.ac.jp
authors.forename: Takehiko
authors.initials: T
authors.lastname: Yoshimitsu
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Arano
authors.forename: Hiroto
authors.initials: H
authors.lastname: Nagaoka