Anti-inflammatory strategies in coronary atherosclerosis.
Recent evidence has demonstrated that inflammation plays an important role in the progression of coronary atherosclerosis. This review focuses on acute coronary syndromes and examines some novel therapeutic strategies aimed at manipulating the inflammatory environment in these patients in order to reduce the subsequent major adverse coronary event rate following myocardial infarction.
Burton
Paul B J
PB
Amgen Inc, Amgen Center Drive, Building 38, Room 3A-5-1, Thousand Oaks, CA 91320, USA. burtonp@amgen.com
Daniel
Thomas O
TO
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000188:drug therapy*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology
D000893:Anti-Inflammatory Agents