title: Treatment of renal nephroblastoma in an adult dog.
abstract: An 8-year-old Labrador retriever was diagnosed with a unilateral malignant nephroblastoma and hypertrophic osteopathy. The histopathologically malignant tumor was confined to the renal capsule, but the sarcomatous component was anaplastic, resulting in its classification as a Stage I tumor with unfavorable histopathology. The dog was treated with unilateral nephrectomy, vincristine, and doxorubicin. This dog has remained disease free for >25 months. Reported treatments of renal nephroblastoma in the dog have not described disease-free intervals of >8 months.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Box 1071, Knoxville, Tennessee 37901-1071, USA.
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Seaman
authors.forename: Clark S
authors.initials: CS
authors.lastname: Patton
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D004285:Dogs; D004317:Doxorubicin / Q000008:administration & dosage; D004487:Edema / Q000209:etiology / Q000662:veterinary; D005552:Forelimb; D006417:Hematuria / Q000209:etiology / Q000662:veterinary; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D009367:Neoplasm Staging; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000000981:diagnostic imaging / Q000209:etiology / Q000662:veterinary; D011859:Radiography; D014750:Vincristine / Q000008:administration & dosage; D009396:Wilms Tumor / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D014750:Vincristine; D004317:Doxorubicin