[Signal transduction pathways in cardiac myocyte hypertrophy].
Cardiac hypertrophy is the consequence of hypertrophic stimulus-induced changes in gene expression, which is linked by intracellular signal transduction. It is likely, however, that there are "molecular phenotypic" differences underlying cardiac hypertrophy triggered by different stimuli, which is caused by the different signal pathways that they initiated. Studying on the signal pathways in cardiac myocyte hypertrophy contributed to elucidate the cellular and molecular mechanisms of cardiac hypertrophy and might find some new strategies for the prevention of cardiac hypertrophy.
Fu
M G
MG
Institute of Cardiovascular Research, First Hospital, Beijing Medical University, Beijing 100034.
Tang
C S
CS
D000804:Angiotensin II / Q000502:physiology*; D000818:Animals; D002118:Calcium / Q000502:physiology; D006332:Cardiomegaly / Q000503:physiopathology*; D002395:Catecholamines / Q000502:physiology; D016228:Endothelial Growth Factors / Q000502:physiology; D006801:Humans; D015398:Signal Transduction
D002395:Catecholamines; D016228:Endothelial Growth Factors; D000804:Angiotensin II; D002118:Calcium