[Study of bacteriology on local application of Tinidazole stilus in treatment for periodontitis].
OBJECTIVE
The study was designed to evaluate the antiseptic efficacy of Tinidazole stilus against periodontal pathogen.


METHODS
A total of 41 patients with periodontitis were included in this study. 26 of them were treated by Tindazole stilus and other 15 cases were treated by metronidazole stilus as controls. The prevalence of subgingival bacteria from both group were examined.


RESULTS
The eliminate rates for Black pigmented anaerobic rod (Porphyromonas gingivalis, Prevotella intermedius, Prevotella melaninogenicus), Fusobacteriums, Prevotella oris, Prevotella oralis, Eubacterium and Actinomyces were 95.8% 94.1%, 83.3% and 76.5%. The anti-bacterial efficiency of Tinidazole against periodontal pathogen was significantly higher than that of metronidazole (P < 0.05).


CONCLUSIONS
It appears to be effective to use Tinidazole stilus as local application against periodontal pathogens.
Wang
H
H
Department of Stomatology, Third People's Hospital of Chengdu.
Luo
J
J
Su
W
W
He
Q
Q
Huang
X
X
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D010518:Periodontitis / Q000188:drug therapy* / Q000382:microbiology; D016966:Porphyromonas gingivalis / Q000187:drug effects; D001443:Prevotella melaninogenica / Q000187:drug effects; D014011:Tinidazole / Q000008:administration & dosage* / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014011:Tinidazole; D008795:Metronidazole