[Enantiomeric separation of ketoprofen on an ovomucoid column].
The enantiomeric separation of ketoprofen in three mobile phase systems on an ovomucoid (OVM) chiral stationary phase (CSP) column was investigated. Suitable chromatographic conditions for simultaneous separation of the two pairs of enantiomers of ketoprofen and its methyl ester were adopted. All of the four compounds occuring in the process of enzymatic stereoselective hydrolysis or esterification can be simultaneously separated.
Wang
X J
XJ
Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, China. wxj111@263.net
Cao
G F
GF
Xu
S W
SW
D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D007660:Ketoprofen / Q000737:chemistry / Q000302:isolation & purification*; D010059:Ovomucin; D013237:Stereoisomerism
D010059:Ovomucin; D007660:Ketoprofen