[Changes in rat erythrocyte hemorheology caused by morphine dependence].
This study was aimed at the effect of morphine on the biomechanics properties of rat erythrocyte membrane in vivo and in vitro. The shear elastic modulus (E) and the surface viscotsity viscosity (micron) of rat erythrocyte membrane was measured by using the method of the new ektacytometry. The changes in hemorheology caused by morphine dependence were investigated and the mechanisms of the changes are suggested.
Xie
X
X
Department of Biophysics, Beijing Medical University, Beijing 100083.
Huang
L
L
Wen
Z
Z
Cheng
B
B
D000818:Animals; D002478:Cells, Cultured; D004907:Erythrocyte Deformability / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008560:Membrane Fluidity / Q000187:drug effects; D009020:Morphine / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
D009020:Morphine