title: [Hemorheologic change after strong blood flow disturbance caused by gunshot and its influence on the prognosis of the wounded animals].
abstract: Three types of experimental models were used in this study: 1. Both thighs of dogs were wounded by 5.56 mm bullet. 2. Femoral artery and vein were tied at the time of wounding. 3. Shock caused by simply bleeding the dogs' femoral arteries. We observed the characteristics of change hemorheology and analyzed its effects on the wounded dogs. The results showed that strong blood flow disturbances always brought about hemorheologic changes such as rapidly increased blood viscosity and red cell's aggregation index and the simultaneous phenomenon of blood concentration. These may be related to extensive endothelium injury and destruction of a number of blood cells caused by disturbance wave. The above change may give rise to abnormality of microcirculation and disturbance of matter transmission; in that sense, it may provide the physiopathologic basis for the occurrence and development of the complication.
authors.affiliation: Research Institute of Surgery, Daqing Hospital, Third Military Medical University, Chongqing 400042.
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: D
authors.initials: D
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.forename: W
authors.initials: W
authors.lastname: Lian
authors.forename: X
authors.initials: X
authors.lastname: Lai
authors.forename: G
authors.initials: G
authors.lastname: Wu
authors.forename: L
authors.initials: L
authors.lastname: Chen
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D004195:Disease Models, Animal; D004285:Dogs; D018056:Hemorheology; D014948:Wounds, Gunshot / Q000503:physiopathology*