Proteomic technologies to study diseases of the lymphatic vascular system.
Now that the human genome has been mapped, a new challenge has emerged: deciphering the various products of individual genes. Consequently, new proteomic technologies are being developed to monitor and identify protein function and interactions responsible for the total activities of the cell. The application of these new proteomic technologies to study cellular activities, will lead to a faster sample throughput and increased sensitivity for the detection of individual proteins, thus providing major opportunities for the discovery of new biomarkers for the early detection of protein alterations associated with the progression of the disease state.
Leak
Lee V
LV
Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Petricoin
Emanuel F
EF
Jones
Michael
M
Paweletz
Cloud P
CP
Ardekani
Ali M
AM
Fusaro
Vincent A
VA
Ross
Sally
S
Liotta
Lance A
LA
D000818:Animals; D006801:Humans; D008206:Lymphatic Diseases / Q000235:genetics* / Q000503:physiopathology*; D008208:Lymphatic System / Q000503:physiopathology*; D009363:Neoplasm Proteins / Q000235:genetics; D011506:Proteins / Q000235:genetics; D020543:Proteome; D012107:Research Design
D009363:Neoplasm Proteins; D011506:Proteins; D020543:Proteome