Cardiovascular disease and long-chain omega-3 fatty acids.
OBJECTIVE
Of all known dietary factors, long-chain omega-3 fatty acids may be the most protective against death from coronary heart disease. New evidence has confirmed and refined the cardioprotective role of these fatty acids.


RESULTS
Omega-3 fatty acid supplementation reduces the risk of sudden cardiac death and death from any cause within 4 months in post-myocardial infarction patients. Evidence continues to accrue for benefits in the primary prevention of coronary heart disease and stroke, and an anti-arrhythmogenic mechanism is emerging as the most likely explanation.


CONCLUSIONS
Current evidence suggests that individuals with coronary artery disease may reduce their risk of sudden cardiac death by increasing their intake of long-chain omega-3 fatty acids by approximately 1 g per day.
Harris
William S
WS
Lipid and Diabetes Research Center, Saint Luke's Hospital, University of Missouri - Kansas City School of Medicine, 64111, USA. wharris@saint-lukes.org
Park
Yongsoon
Y
Isley
William L
WL
D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D002319:Cardiovascular System / Q000187:drug effects*; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans
D015525:Fatty Acids, Omega-3