[Fos expression in rat skin after different incised wound healing interval].
OBJECTIVE
To investigate the expression of c-fos in rats' skin during wound healing.


METHODS
Immunohistochemistry was conducted on paraffin section from incised wounding model of rat skin.


RESULTS
Fos protein improved from the time of 10 min after wounding in the wound edge, then it reached peak at 3 h. 24 h after injury, the quantity of Fos expression had no difference with that of normal skin.


CONCLUSIONS
Fos is sensitive after wound, but should be used with other criteria in wounding interval estimation as it's unstediness.
Liu
N G
NG
Institution of Forensic Sciences of Ministry of Justice, Shanghai 200063. liuningguo@163.net
Zhao
Z Q
ZQ
Gu
Y J
YJ
Chen
Y J
YJ
Yan
Z K
ZK
Liao
Y P
YP
D000818:Animals; D017781:Genes, Immediate-Early; D007150:Immunohistochemistry; D008297:Male; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000293:injuries* / Q000378:metabolism*; D013997:Time Factors; D014947:Wounds and Injuries / Q000378:metabolism
D016760:Proto-Oncogene Proteins c-fos