title: Clinical ECG mapping and imaging of cardiac electrical excitation.
abstract: Combining electrocardiographic mapping and 3D+time anatomical data enables noninvasively the imaging of the electrical excitation sequence in the human heart. A bidomain-theory based surface heart model activation time imaging approach was employed to image single beat data of atrial and ventricular depolarisation. Activation time maps were reconstructed for three patients who underwent an electrophysiologic study. The sinus rhythm and a rhythm according to a pacing protocol were reconstructed for two patients. For the third patient the accessory pathway of the WPW syndrome was localized. For focal arrhythmias, this model-based imaging approach might allow the guidance and evaluation of antiarrhythmic interventions, for instance, in case of catheter ablation or drug therapy.
authors.affiliation: Institute for Medical Signal Processing and Imaging, University for Health Informatics and Technology Tyrol, Innsbruck, Austria. bernhard.tilg@umit.at
authors.forename: Bernhard
authors.initials: B
authors.lastname: Tilg
authors.forename: Friedrich
authors.initials: F
authors.lastname: Hanser
authors.forename: Robert
authors.initials: R
authors.lastname: Modre-Osprian
authors.forename: Gerald
authors.initials: G
authors.lastname: Fischer
authors.forename: Bernd
authors.initials: B
authors.lastname: Messnarz
authors.forename: Thomas
authors.initials: T
authors.lastname: Berger
authors.forename: Florian
authors.initials: F
authors.lastname: Hintringer
authors.forename: Otmar
authors.initials: O
authors.lastname: Pachinger
authors.forename: Franz Xaver
authors.initials: FX
authors.lastname: Roithinger
mesh_terms: D000328:Adult; D000368:Aged; D001282:Atrial Flutter / Q000503:physiopathology; D018780:Body Surface Potential Mapping / Q000379:methods*; D022062:Electrophysiologic Techniques, Cardiac; D006325:Heart Atria / Q000503:physiopathology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008953:Models, Anatomic; D014927:Wolff-Parkinson-White Syndrome / Q000503:physiopathology