Histological and electrophysiological assessment of the results of primary and secondary neurorrhaphy in a rabbit model.
The effect of the timing of neurorrhaphy on neuromuscular function was studied. The gastrocnemius neuromuscular units of 22 rabbits were used, with repairs performed immediately and 3 weeks after nerve transection. At the end of 3 months, electrophysiological and histological results were compared. The study found that there was a higher rate of neuromuscular function return in primarily sutured nerves (88.0%) than in nerves repaired by secondary suture (63.0%). The histological examination also confirmed a better preserved microscopic structure of the primary repair group.
Karaismailoglu
T Nedim
TN
Department of Orthopaedics and Trauma Surgery, Faculty of Medicine, Ondokuz Mayis University, 55139 Kurupelit-Samsun, Turkey.
Tasci
Niyazi
N
Baris
Sancar
S
Tomak
Yilmaz
Y
Piskin
Ahmet
A
D000200:Action Potentials; D000818:Animals; D023421:Models, Animal; D010525:Peripheral Nerves / Q000502:physiology / Q000601:surgery*; D011817:Rabbits; D013536:Suture Techniques; D013979:Tibial Nerve / Q000502:physiology / Q000601:surgery; D013997:Time Factors