Major-to-ultratrace elements in bone-marrow fluid as determined by ICP-AES and ICP-MS.
The major-to-ultratrace elements in human bone-marrow fluid were determined by ICP-AES (inductively coupled plasma atomic emission spectrometry), and ICP-MS (inductively coupled plasma mass spectrometry). The bone-marrow fluid sample was centrifuged prior to acid digestion to exclude the bone piece from bone marrow, and then digested with nitric acid. As a result, 20 elements could be determined over the concentration range from 1610 microg g(-1) for Na to 0.00043 microg g(-1) for W. It was found that Fe, Zn and Sb were enriched by ca. 264-, 7- and 15-fold, respectively, in bone-marrow fluid, compared to those in human blood serum. Alkali metals (K, Rb, Cs), except for Na, were also significantly enriched in bone-marrow fluid. Furthermore, the concentrations of various elements, such as Fe, P, Al, Zn, Cu, Se, Zr, Sn, Ag and W, were significantly higher than those in open seawater.
Hasegawa
Takuya
T
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.
Matsuura
Hirotaka
H
Inagaki
Kazumi
K
Haraguchi
Hiroki
H
D001853:Bone Marrow / Q000737:chemistry*; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D012623:Seawater / Q000737:chemistry; D014131:Trace Elements / Q000032:analysis* / Q000097:blood
D014131:Trace Elements