Reference values for the bone marrow aspirates in adult dogs.
Reference ranges for each cell type and six different ratios (M : E ratio = quotient of number of myeloid cells/erythroid precursors; different maturation ratios) were calculated for bone marrow aspirates of adult dogs. These values were based on 2.5 and 97.5% percentiles of differentials of 1000 cells in bone marrow aspirates of 92 healthy 1-8-year-old dogs. The results of intact male and female dogs were compared. No distinct sex-related differences were found (P > 0.05). A wide physiological range was observed in almost all bone marrow cells resulting in broad reference ranges for the ratios. The clinically relevant M : E ratio varied between 0.45 and 2.87. The accurate cytological examination of bone marrow based on the reference ranges presented in this study requires preparation of high-quality bone marrow films with minimal blood contamination.
Mischke
R
R
Clinic for Small Animals, School of Veterinary Medicine, Hannover, Germany. reinhard.mischke@tiho-hannover.de
Busse
L
L
D000818:Animals; D001707:Biopsy, Needle / Q000662:veterinary; D001853:Bone Marrow / Q000473:pathology; D001854:Bone Marrow Cells / Q000145:classification* / Q000166:cytology*; D001856:Bone Marrow Examination / Q000662:veterinary; D004285:Dogs / Q000502:physiology*; D005260:Female; D008297:Male; D012016:Reference Values