Aerobic soil metabolism of a new herbicide, LGC-42153.
To elucidate the fate of a new sulfonylurea herbicide, LGC-42153 [N-((4,6-dimethoxypyrimidin-2-yl)aminocarbonyl)-2-(1-methoxyacetoxy-2-fluoropropyl)-3-pyridinesulfonamide], in soil, an aerobic soil metabolism study was carried out for 120 days with [(14)C]LGC-42153 applied to a loamy soil. The material balance ranged from 90.7 to 101.5% of applied herbicide. The half-life of [(14)C]LGC-42153 was calculated to be approximately 9.0 days. The degradation products resulted from the cleavage of the sulfonylurea bridge. The metabolites identified during the study were N-((4,6-dimethoxypyrimidin-2-yl)aminocarbonyl)-2-(1-hydroxy-2-fluoropropyl)-3-pyridinesulfonamide, 2-(1-hydroxy-2-fluoropropyl)-3-pyridinesulfonamide, and 4,6-dimethoxy-2-aminopyrimidine. No significant volatile products or [(14)C]carbon dioxide was observed during the study. Nonextractable (14)C-residue reached 14.4-30.5% of applied material at 120 days after treatment, and radioactivity was distributed mostly in the humin and fulvic acid fractions.
Kim
Jin
J
School of Agricultural Biotechnology, Seoul National University, 103 Seodundong, Suwon 441-744, Korea.
Liu
Kwang-Hyeon
KH
Kang
Seung-Hun
SH
Koo
Suk-Jin
SJ
Kim
Jeong-Han
JH
D000332:Aerobiosis; D002250:Carbon Radioisotopes; D006207:Half-Life; D006540:Herbicides / Q000737:chemistry* / Q000378:metabolism*; D011743:Pyrimidines / Q000737:chemistry* / Q000378:metabolism*; D012987:Soil / Q000032:analysis*; D012988:Soil Microbiology; D013449:Sulfonamides / Q000737:chemistry* / Q000378:metabolism*
D002250:Carbon Radioisotopes; D006540:Herbicides; C471785:N-((4,6-dimethoxypyrimidin-2-yl)aminocarbonyl)-2-(1-methoxyacetoxy-2-fluoropropyl)-3-pyridinesulfonamide; D011743:Pyrimidines; D012987:Soil; D013449:Sulfonamides