title: [The determination of activated partial thromboplastin time, coagulate time and thrombin time in patients with epistaxis of indeterminate cause].
abstract: OBJECTIVE
  To explore the coagulation mechanism of indeterminate epistaxis.
  
  
  METHODS
  36 cases with epistaxis of indeterminate cause were studies by mean of detecting activated partial thromboplastin time (APTT), coagulate time (CT) and thrombin time. The results of first APTT, APTT after 8 min and CT were observed.
  
  
  RESULTS
  1. The first APTT in epistaxis and normal group didn't show statistical difference (P > 0.05). But the APTT after 8 min in epistaxis were significantly different compared with the first APTT and that in normal group (P < 0.01). 2. The CT prolonged in 33.3% patients with epistaxis, which was higher significantly than that in the normal group (P < 0.01). (3) The epistaxis thrombin time (TT) was longer than that in normal group.
  
  
  CONCLUSIONS
  The result suggest that during blood coagulation in indeterminate epistaxis, the activated factors in internal coagulating system may decompose more quickly than that in normal group. Antiagglutinating factors increase in blood.
authors.affiliation: Department of Otolaryngology, First Clinic Medical College of Guangxi Medical University, Nanning 530021.
authors.forename: G W
authors.initials: GW
authors.lastname: Huang
authors.forename: L L
authors.initials: LL
authors.lastname: Zhan
authors.forename: J D
authors.initials: JD
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D001778:Blood Coagulation Disorders / Q000150:complications; D002648:Child; D002675:Child, Preschool; D004844:Epistaxis / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D013918:Thrombin Time; D014914:Whole Blood Coagulation Time