title: Absolute configuration of a tetrahydrophenanthrene from Heliotropium ovalifolium by LC-NMR of its Mosher esters.
abstract: A new tetrahydrophenanthrene (1, (1R,2R)-1-hydroxy-2-methoxy-6,9-dimethyl-2,3-dihydrophenanthren-4(1H)-one (heliophenanthrone)) has been isolated from the aerial parts of Heliotropium ovalifolium. Its structure was elucidated on the basis of spectroscopic data, and the absolute configuration of the asymmetric centers was determined from LC-NMR data of the Mosher ester derivatives.
authors.affiliation: Institut de Pharmacognosie et Phytochimie, Université de Lausanne, BEP, CH-1015 Lausanne, Switzerland.
authors.forename: David
authors.initials: D
authors.lastname: Guilet
authors.forename: Alain
authors.initials: A
authors.lastname: Guntern
authors.forename: Jean-Robert
authors.initials: JR
authors.lastname: Ioset
authors.forename: Emerson F
authors.initials: EF
authors.lastname: Queiroz
authors.forename: Karine
authors.initials: K
authors.lastname: Ndjoko
authors.forename: Chris M
authors.initials: CM
authors.lastname: Foggin
authors.forename: Kurt
authors.initials: K
authors.lastname: Hostettmann
mesh_terms: D004952:Esters / Q000737:chemistry; D028162:Heliotropium / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010616:Phenanthrenes / Q000737:chemistry* / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D015030:Zimbabwe
chemical_list: D004952:Esters; D010616:Phenanthrenes; C473999:heliophenanthrone