title: [Cut-off level of glycosylated hemoglobin indicating the development of complications in type 2 diabetes mellitus].
abstract: Prevention of chronic complications is very important in the management of type 2 diabetes, and the availability of a laboratory test individuating at risk subjects should have a marked usefulness. This study sought by the method of ROC curves the cut-off of glycated haemoglobin discriminating the subjects with microvascular, neurologic and renal complications from those without. The cut-off was identified at a glycated haemoglobin level of 7.95, showing a sensitivity of 74.8% and a specificity of 73.3%, which makes it a possible tool for evaluating the risk of complications in type 2 diabetes.
authors.affiliation: Medicina Riabilitativa II, Istituti Clinici di Perfezionamento, Milano. cristoforo.incorvaia@fastwebnet.it
authors.forename: Cristoforo
authors.initials: C
authors.lastname: Incorvaia
authors.forename: Franco
authors.initials: F
authors.lastname: Maraffi
authors.forename: Raffaella
authors.initials: R
authors.lastname: Megali
authors.forename: Fabio
authors.initials: F
authors.lastname: Nitti
authors.forename: Mario
authors.initials: M
authors.lastname: Fumagalli
mesh_terms: D016001:Confidence Intervals; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D012372:ROC Curve; D012680:Sensitivity and Specificity
chemical_list: D006442:Glycated Hemoglobin