Reactions of hemopoietic granulocytic stem in hypoxia of different severity.
We studied the reactions of granulocytic hemopoietic stem after acute hypoxia and during the development of posthypoxic encephalopathy. Damage to brain structures was associated with intensification of the bone marrow hemopoiesis due to activation of hemopoiesis-inducing microenvironment and more intense formation of hemopoietic islets, despite reduced proliferative capacity of granulocytic precursors.
Zyuz'kov
G N
GN
Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Russia.
Gur'yantseva
L A
LA
Suslov
N I
NI
Dygai
A M
AM
Gol'dberg
E D
ED
D000818:Animals; D001854:Bone Marrow Cells / Q000473:pathology; D003114:Colony-Forming Units Assay; D006098:Granulocytes / Q000473:pathology*; D006412:Hematopoietic Stem Cells / Q000473:pathology*; D000860:Hypoxia / Q000473:pathology*; D002534:Hypoxia, Brain / Q000473:pathology*; D007700:Kinetics; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA