title: Algorithm for using a long-pulsed Nd:YAG laser in the treatment of deep cutaneous vascular lesions.
abstract: BACKGROUND
  Conventional therapies for deep cutaneous vascular anomalies have demonstrated poor efficacy and many side effects. New laser systems offer greater potential to treat these difficult lesions, but the lack of specific treatment guidelines has restricted consistent success.
  
  
  OBJECTIVE
  To establish a rational, user-friendly algorithm that incorporates basic components of deep vascular lesions to define the correct laser settings required for safe, effective, and reproducible treatment.
  
  
  METHODS
  Within 18 months, 162 deep vascular lesions of various types and anatomic sites were evaluated for vessel size, depth, color, and pressure. An algorithm incorporating these characteristics was employed to determine laser parameter settings. Using a high-peak power, long-pulse 1064-nm Nd:YAG laser system, the vascular lesions were then treated.
  
  
  RESULTS
  Within 6 months of follow-up, 80% of treated areas demonstrated a 50% or greater resolution after a single treatment session, with complete clearance shown in 19%. Only minimal and transient side effects were observed. Of note, 74% of areas on the extremities and 83% within the oral cavity showed a 50% or greater resolution after one treatment.
  
  
  CONCLUSIONS
  Previously challenging deep cutaneous vascular anomalies may be safely reduced or cleared with the use of an appropriate laser system and this algorithm-directed technique. This represents a significant breakthrough in the management of vascular lesions.
authors.affiliation: University of Alberta, Canada. groot@compusmart.ab.ac
authors.forename: Don
authors.initials: D
authors.lastname: Groot
authors.forename: Jaggi
authors.initials: J
authors.lastname: Rao
authors.forename: Patricia
authors.initials: P
authors.lastname: Johnston
authors.forename: Thomas
authors.initials: T
authors.lastname: Nakatsui
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D002648:Child; D002675:Child, Preschool; D005260:Female; D006391:Hemangioma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009383:Neoplasms, Vascular Tissue / Q000473:pathology / Q000601:surgery*; D019339:Port-Wine Stain / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000473:pathology / Q000601:surgery*