title: Sudden death of a girl with Prader-Willi syndrome.
abstract: We report on the sudden death of a 3.5-year-old girl with Prader-Willi syndrome (PWS) and 15q11-q13 deletion. She suffered from severe chronic breathing disturbances and recurrent bronchitis. During an episode of acute bronchitis she had a cardiac arrest and died two months later of the sequelae. Brain CT imaging three weeks after the arrest showed bilateral symmetrical haemorrhages in the basal ganglia region. The spatial distribution of the haemorrhages can possibly suggest that the basal ganglia in PWS may be especially susceptible to hypoxemia.
authors.affiliation: Department of Pediatrics, University of Tartu, Tartu, Estonia.
authors.forename: E
authors.initials: E
authors.lastname: Oiglane
authors.forename: K
authors.initials: K
authors.lastname: Ounap
authors.forename: O
authors.initials: O
authors.lastname: Bartsch
authors.forename: R
authors.initials: R
authors.lastname: Rein
authors.forename: T
authors.initials: T
authors.lastname: Talvik
mesh_terms: D002675:Child, Preschool; D002872:Chromosome Deletion; D002884:Chromosomes, Human, Pair 15; D003645:Death, Sudden; D005260:Female; D006801:Humans; D011218:Prader-Willi Syndrome / Q000235:genetics / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed