Lansoprazole ineffective for functional dyspepsia.
Patients with functional dyspepsia, which involves no organic disease and no reflux, do not benefit from lansoprazole, a proton pump inhibitor. Any improvement seen is probably related to a placebo effect. Prescribing proton pump inhibitors for these patients just for their placebo effect is going to further raise health care costs. Antacids and H2 blockers are less expensive alternatives.
Mounsey
Anne L
AL
Department of Family Medicine, University of Virginia Health Care System, Charlottesville, USA. alm2d@virginia.edu