title: Use of octyl-2-cyanoacrylate in cleft lip repair.
abstract: Octyl-2-cyanoacrylate (Dermabond; Ethicon, Somerville, NJ) is a synthetic tissue adhesive recently approved for skin closure. This study was designed to assess its effectiveness for use in clefts lip repairs. Sixty-four patients with unilateral, bilateral, or midline cleft lip defects were repaired. The ages at repair ranged from 4 days to 19 months, with an average of 46.5 days. Follow-up ranged from 6 months to 3 years. No complications were found. Several advantages were observed: shorter operative time, formation of a protective barrier, simplified incision care, no need for suture removal, and improved scar outcome. This study supports octyl-2-cyanoacrylate as an alternative to skin sutures in primary cleft lip repair.
authors.affiliation: Eastern Virginia Medical School, Institute of Craniofacial and Plastic Surgery, Children's Hospital of the King's Daughters, Norfolk, VA, USA.
authors.forename: William P
authors.initials: WP
authors.lastname: Magee
authors.forename: Nicolas
authors.initials: N
authors.lastname: Ajkay
authors.forename: Bernard
authors.initials: B
authors.lastname: Githae
authors.forename: Richard S
authors.initials: RS
authors.lastname: Rosenblum
mesh_terms: D002971:Cleft Lip / Q000601:surgery*; D003487:Cyanoacrylates / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D014014:Tissue Adhesives / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate