title: [Cytogenetic effects of alpha-irradiation due to incorporated 239Pu].
abstract: Intravenous injection of plutonium dioxide with 1-2 microns particle sizes in amount of 92.5, 46.3 and 23.2 kBq/kg of body mass increased the yield of chromosome aberrations in bone marrow cells of rats by 3.7, 2.3 and 1.7 times, correspondingly, in comparison with the spontaneous level. The model of chromosome aberration dependence on dose of radionuclide was developed based on the experimental results.
authors.affiliation: South-Urals Institute of Biophysics, Russian Ministry of Health, Ozersk, 456780 Russia.
authors.forename: M L
authors.initials: ML
authors.lastname: Zakharova
authors.forename: S V
authors.initials: SV
authors.lastname: Osobets
authors.forename: T I
authors.initials: TI
authors.lastname: Uriadnitskaia
authors.forename: A L
authors.initials: AL
authors.lastname: Sokhranich
authors.forename: K N
authors.initials: KN
authors.lastname: Muksinova
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000648:ultrastructure; D002869:Chromosome Aberrations; D008297:Male; D011005:Plutonium / Q000633:toxicity*; D051381:Rats
chemical_list: C026885:plutonium dioxide; D011005:Plutonium