title: Haloacetic acids and trihalomethanes in finished drinking waters from heterogeneous sources.
abstract: Trihalomethanes (THM) and haloacetic acids (HAA) are the most frequent chlorination by-products (CBP) in finished drinking waters. Traditionally, THM have been used as surrogates for CBP although the quantitative association between THM and other CBP is not well established. This problem is addressed in the present study from the analysis of THM and HAA in drinking water samples from four Spanish regions, representing areas with very different CBP composition, e.g. between 86 and 8.0 microg/l of THM and 50-3.0 microg/l of HAA. The resulting dataset exhibit a statistically significant correlation between total THM and HAA (Pearson's correlation coefficient, r(p)=0.815,p<0.0005). Furthermore, specific HAA are highly correlated with specific THM or their combinations. Accordingly, multivariate linear regression analysis of the concentrations observed show that the levels in total and specific HAA can be predicted from the THM content. These results are relevant for epidemiological studies on health effects from CBP exposure since they usually involve comparison of populations consuming waters of very distinct quality.
authors.affiliation: Respiratory and Environmental Health Research Unit, Municipal Institute of Medical Research (IMIM), C/Doctor Aiguader 80, 08003-, Barcelona, Spain. cvillanueva@imim.es
authors.forename: C M
authors.initials: CM
authors.lastname: Villanueva
authors.forename: M
authors.initials: M
authors.lastname: Kogevinas
authors.forename: J O
authors.initials: JO
authors.lastname: Grimalt
mesh_terms: D019342:Acetic Acid / Q000032:analysis* / Q000737:chemistry*; D013030:Spain; D022882:Trihalomethanes / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D018508:Water Purification; D014881:Water Supply / Q000592:standards
chemical_list: D022882:Trihalomethanes; D014874:Water Pollutants, Chemical; D019342:Acetic Acid