title: [A comparative study on the capacities of different strains of Streptococcus sanguis for P-aminobenzoic acid production].
abstract: This study was intended to compare the capacities of different strains of Strep, sanguis for P-Aminobenzoic acid (PABA) production. The synthesis of PABA during the growth of four strains of Strep. sanguis was measured by the reversed-phase high-performance liquid chromatographic method. The results showed that the concentrations of PABA synthesized by S. sanguis 10556, S. sanguis 10557, S. sanguis S34 and S. sanguis H7-4. Were 1.979 +/- 0.081 micrograms/ml, 1.383 +/- 0.193 micrograms/ml, 1.983 +/- 0.052 micrograms/ml and 1.032 +/- 0.229 micrograms/ml, respectively, and in term of PABA concentration, S. sanguis 10556 was significantly different from S. sanguis 10557 and S. sanguis H7-4; S. sanguis S34 was significantly different from S. sanguis 10557 and S. sanguis H7-4. No significant difference was found between S. sanguis 10556 and S. sanguis S34, nor between S. sanguis 10557 and S. sanguis H7-4, either. In conclusion, the method is simple, rapid and accurate. S. sanguis did synthesize PABA, and the difference in ability for PABA formation existed among the four strains of S. sanguis. This study is helpful to researches on the symbiosis between S. sanguis and S. muntans and to determination of their role in the microbial homeostasis of dental plaque.
authors.affiliation: Department of Cariology, School of Stomatology, WCUMS, Chengdu 610041.
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.forename: X
authors.initials: X
authors.lastname: Zhou
authors.forename: T
authors.initials: T
authors.lastname: Hu
authors.forename: B
authors.initials: B
authors.lastname: Guo
authors.forename: P
authors.initials: P
authors.lastname: Zhang
mesh_terms: D010129:4-Aminobenzoic Acid / Q000032:analysis / Q000302:isolation & purification / Q000378:metabolism*; D003773:Dental Plaque / Q000382:microbiology; D006801:Humans; D013295:Streptococcus mutans / Q000378:metabolism; D013298:Streptococcus sanguis / Q000145:classification / Q000378:metabolism*; D013559:Symbiosis
chemical_list: D010129:4-Aminobenzoic Acid