Ent-pimarane type diterpenes from Gnaphalium gaudichaudianum.
Fractionation of the methanol extract of Gnaphalium gaudichaudianum DC afforded one new and six known ent-pimarane diterpenes together with velutin, squalene and stigmasterol. The structure of the new compound was established on the basis of extensive 1D and 2D NMR spectroscopic data interpretation. Two of the isolated compounds exhibited moderate toxicity in the Artemia salina toxicity test.
Meragelman
Tamara L
TL
Departamento de Química Orgánica, Facultad de Ciencias Químicas (IMBIV-CONICET), Universidad Nacional de Córdoba, Pabellón de Ciencias II, Ciudad Universitaria, Córdoba, Argentina.
Silva
Gloria L
GL
Mongelli
Elena
E
Gil
Roberto R
RR
D045784:Abietanes; D000818:Animals; D001118:Argentina; D001156:Artemia / Q000187:drug effects*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D036622:Gnaphalium / Q000737:chemistry*; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism
D045784:Abietanes; D004224:Diterpenes; C433018:pimarane