[Tetracycline tracing of artificial bone composite with high biological induction in repairing bone defect].
The tetracycline tracing method was adopted to study the new bone formation at the early stage of two different composite artificial bones (HA-bBMP-Co and HA-Co)in repairing segmental bone defect in 8 rabbits. The results indicated that from the early stage even just one week after implantation, HA-bBMP-Co acted much faster than HA-Co did in inducing new bone formation, suggesting that HA-bBMP-Co be of good quality in ferms of histo-compatibility and osteoinduction.
Fei
W
W
Department of Oral and Maxillofacial Surgery, West China University of Medical Sciences, Chengdu 610041.
Wang
D
D
Liu
S
S
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000627:therapeutic use; D018786:Bone Substitutes / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use; D005260:Female; D006882:Hydroxyapatites / Q000627:therapeutic use; D008297:Male; D010012:Osteogenesis; D011817:Rabbits; D013752:Tetracycline; D014457:Ulna / Q000601:surgery
D019485:Bone Morphogenetic Proteins; D018786:Bone Substitutes; D006882:Hydroxyapatites; D003094:Collagen; D013752:Tetracycline