title: [Effect of the bonding amounts of chiral ligand exchange chromatographic stationary phases on the enantioseparation of amino acids].
abstract: L-proline chiral stationary phases with various bonding amounts for ligand exchange chromatography were prepared by treating silica gel with 3-glycidoxypropyltrimethoxysilane and bonding L-proline. The bonding amounts of L-proline chiral stationary phase were controlled effectively and characterized by IR and elemental analysis. Some DL-amino acids were separated and the influences of the bonding amounts on the efficiency of resolution of DL-amino acids by ligand exchange chromatography were briefly discussed and explained by the mechanism of the separation.
authors.affiliation: Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China. zxylz@yahoo.com
authors.forename: Xin-yi
authors.initials: XY
authors.lastname: Zhu
authors.forename: Xiao-qian
authors.initials: XQ
authors.lastname: Han
authors.forename: Bang-feng
authors.initials: BF
authors.lastname: Qi
authors.forename: Yong-min
authors.initials: YM
authors.lastname: Li
authors.forename: Sheng-xiang
authors.initials: SX
authors.lastname: Jiang
authors.forename: Li-ren
authors.initials: LR
authors.lastname: Chen
mesh_terms: D000596:Amino Acids / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation* / Q000379:methods; D002942:Circular Dichroism; D006860:Hydrogen Bonding; D008024:Ligands; D011392:Proline / Q000302:isolation & purification; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014443:Tyrosine / Q000302:isolation & purification
chemical_list: D000596:Amino Acids; D008024:Ligands; D014443:Tyrosine; D011392:Proline