title: Identification and characterization of a new member of serpin family- HongrES1 in rat epididymis.
abstract: A full length cDNA named HongrES1 was isolated and cloned by screening rat epididymis cDNA library using a mouse EST as a probe and 5'RACE followed. It contained 1590bp nucleotides and its predicted protein had 415 amino acid residues including a serpin (serine protease inhibitor) conserved domain. Tissue distribution pattern showed it was specifically expressed in adult rat epididymis; moreover, in situ hybridyzation indicated this gene was expressed in a limited region of the cauda epididymis near vas deference. Such kind of expression pattern sugested that HongrES1 had potential function in male reproduction.
authors.affiliation: State Key Laboratory of Molecular Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
authors.forename: Zhi Hong
authors.initials: ZH
authors.lastname: Hu
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
authors.forename: Quan
authors.initials: Q
authors.lastname: Shang
authors.forename: Min
authors.initials: M
authors.lastname: Zheng
authors.forename: Jun
authors.initials: J
authors.lastname: Yang
authors.forename: Yong Lian
authors.initials: YL
authors.lastname: Zhang
mesh_terms: D000595:Amino Acid Sequence / Q000235:genetics; D000818:Animals; D001483:Base Sequence / Q000235:genetics; D002454:Cell Differentiation / Q000502:physiology*; D018076:DNA, Complementary / Q000032:analysis; D004822:Epididymis / Q000166:cytology / Q000378:metabolism*; D004847:Epithelial Cells / Q000166:cytology / Q000378:metabolism*; D008297:Male; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D012098:Reproduction / Q000502:physiology; D015843:Serpins / Q000235:genetics / Q000302:isolation & purification*; D013094:Spermatozoa / Q000166:cytology / Q000378:metabolism*
chemical_list: D018076:DNA, Complementary; D012333:RNA, Messenger; C476408:Serpina16 protein, rat; D015843:Serpins