[The rebound of nasal resistance after decongestant used in nose].
OBJECTIVE
To investigate the effect of decongestant on nasal resistance so as to provide theories for studing rhinitis medicamentosa.


METHODS
The changes of nasal blockage in 92 cases of acute rhinitis and chronic rhinitis after using decongestants were recorded, and the nasal resistance in 39 cases were measured by active anterior rhinomanometry.


RESULTS
According to the diseases and decongestants used, the percentage of nasal resistance rebound were 63.5%, 31.2%, 32.2%, 8.6% in 4 groups of investigated patients and 50%, 20%, 75% in 3 groups of measured patients respectively.


CONCLUSIONS
Decongestants can cause the rebound of nasal resistance, which related to the diseases and the decongestants used. The mechanism may be that the factors dilating the vasa in nasal mucosa are activated.
Shen
J
J
Department of Otorhinolaryngology, Union Hospital of Tongji Medical University, Wuhan 430022.
Huang
X
X
Xiang
J
J
Shu
H
H
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014663:Nasal Decongestants / Q000008:administration & dosage / Q000009:adverse effects*; D009297:Nasal Mucosa / Q000098:blood supply; D015508:Nasal Obstruction / Q000139:chemically induced*; D009666:Nose / Q000502:physiology; D012220:Rhinitis / Q000139:chemically induced* / Q000188:drug therapy; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
D014663:Nasal Decongestants; D014662:Vasoconstrictor Agents