title: [Genetic-epidemiologic study of reproductive outcomes in the Ozersk population, located in "Maiak" control area].
abstract: In the population of Ozyorsk town situated in the control area of the nuclear enterprise (Production Association "Mayak") the number of pregnancies and its outcomes was studied in cohort of 2.258 women of completed fertility. The mean number of pregnancies per woman is 5.6 +/- 0.07. The mean size of family is 1.9 +/- 0.02. It was estimated that 2.7% of women had no pregnancies, 4.0% of women had no delivery till the end of their reproductive performance. 4.65% of women contributed nothing to the genofond of the next generation, i.e., they had not any children lived till their reproductive performance (20 years). The Crow Index of Opportunity for Selection and its components connected with differential fertility and differential mortality were estimated. In the population under study tow components of selection--selection at the prenatal stages (72.6%) and selection associated with infertility--are shown to be significant.
authors.affiliation: South-Ural Institute of Biophisics, Russian Ministry of Healrh, Ozyorsk, Chelyabinsk Region, 456780 Russia. Kurbatov@fib1ko.chel-65.chel.su
authors.forename: A V
authors.initials: AV
authors.lastname: Kurbatov
authors.forename: I A
authors.initials: IA
authors.lastname: Vologodskaia
authors.forename: E S
authors.initials: ES
authors.lastname: Grigor'eva
mesh_terms: D015331:Cohort Studies; D004781:Environmental Exposure; D005260:Female; D005298:Fertility / Q000235:genetics / Q000528:radiation effects*; D006801:Humans; D011247:Pregnancy; D018873:Pregnancy Rate; D012426:Russia / Q000453:epidemiology