title: [A clinical analysis of cholesterol granuloma following chronic suppurative otitis media].
abstract: OBJECTIVE
  To investigate the pathophysiological mechanism, clinical menifestation and radiographic diagnosis of cholesterol granuloma following chronic suppurative otitis media.
  
  
  METHODS
  Six cases of CG following chronic suppurative otitis media, confirmed by surgery and pathology, were reviewed and analyzed.
  
  
  RESULTS
  CG frequently accompanied with other middle ear diseases, and was shown as a high signal intensity on both T1-and T2-weighted images in magnetic resonance imaging(MRI).
  
  
  CONCLUSIONS
  It was postulated that the obstruction of pneumatized temporal bone air cell, caused by other middle ear diseases such as cholesteatoma and tympanosclerosis, might be the pathophysiological mechanism of CG. The evaluations of computed tomography (CT) and clinical manifestation were limited to distinguish CG from cholesteatoma or other neoplasm, while the MRI can be of great value to characteristic diagnosis.
authors.affiliation: Department of Otorhinolaryngology, EENT Hospital, Shanghai Medical University, Shanghai 200031.
authors.forename: L
authors.initials: L
authors.lastname: Fang
authors.forename: T
authors.initials: T
authors.lastname: Zhang
authors.forename: L
authors.initials: L
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002784:Cholesterol; D002908:Chronic Disease; D005260:Female; D015745:Granuloma, Foreign-Body / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000150:complications*
chemical_list: D002784:Cholesterol