title: [The relation between translation speed and protein secondary structure].
abstract: Based on the statistical analysis of 119 human and 92 E. coli proteins it was found that for both human and E. coli, the mRNA sequences consisting of tri-codon and tetra-codon with high translation speed preferably code for alpha helices more than for coils. For beta strand, the preference/avoidance oscillates with the translation speed. Moreover, the non-homogeneous usages of tri-codon and tetra-codon with different translation speeds in a given secondary structure have also been found. These results cannot be simply explained by the effect of stochastic fluctuation.
authors.affiliation: Kunming Institute of Zoology, the Chinese Academy of Sciences, China.
authors.forename: Xiao-Qin
authors.initials: XQ
authors.lastname: Li
authors.forename: Liao-Fu
authors.initials: LF
authors.lastname: Luo
authors.forename: Ci-Quan
authors.initials: CQ
authors.lastname: Liu
mesh_terms: D003062:Codon / Q000235:genetics; D029968:Escherichia coli Proteins / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008957:Models, Genetic; D014176:Protein Biosynthesis / Q000235:genetics*; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics
chemical_list: D003062:Codon; D029968:Escherichia coli Proteins; D011506:Proteins; D012333:RNA, Messenger