Nano-kinetics of probe-particles in solution visualized by a pin-fiber video scope.
The nano-kinetics of colloidal particles and living cells with the colloidal particles were visualized by a newly developed video scope. The system of the new video scope has a feature of fine controlling the illumination conditions by using a single optical fiber. This characteristic enables one to obtain clear images of living cells and the motions of colloidal particles by light-scattering effects. In the experiments, RBL-2H3 cells and gold colloidal particles were observed. Scattering images with high contrast and a dark background like in dark-field observations could be attained. In the experiments, a pulsed laser was also applied. The results obtained in this study could validate the effectiveness and possibility of a new video scope for applications to biological and biomedical fields.
Suzuto
Masashi
M
Graduate School of Medical Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
Hirakawa
Yasuyuki
Y
Ohnishi
Hitoshi
H
Tachino
Shinji
S
Shingaki
Tomoteru
T
Eyring
Edward M
EM
Masujima
Tsutomu
T
D000818:Animals; D002460:Cell Line; D007700:Kinetics; D008853:Microscopy / Q000379:methods*; D036103:Nanotechnology; D012996:Solutions
D012996:Solutions