title: [A case of subcutaneous malignant lymphoma with dura mater lesion].
abstract: A 63-year-old male was admitted to our hospital, complaining of a scalp mass located at the frontoparietal area of his head. He noticed that it had been growing for 2 months. The mass was elastic hard and non-moving. Computed tomography demonstrated a subcutaneous mass with low density and which was enhanced homogeneously. The skull just below the mass was slightly destroyed, but the structure remained. Magnetic resonance imaging (MRI) demonstrated a mass with low signal intensity on both the T1 weighted image and the T2 weighted image. Gd-DTPA study showed homogeneous enhancement and showed also that the dura just below the mass was enhanced. At this point we couldn't diagnose it confidently, but suspected this lesion to be a malignant lymphoma. We made a general examination, but no other lesion was found. A biopsy of the subcutaneous mass was performed under local anesthesia. The histological diagnosis was large-cell type B-Cell lymphoma. The tumor was treated with chemotherapy, CHOP (cyclophosphamid, doxorubicin, vincristin predonisolone). It responded to this chemotherapy and disappeared. We treated this lesion without radiation therapy. We report a case of subcutaneous malignant lymphoma treated successfully with a minimum invasive method.
authors.affiliation: Department of Neurosurgery, National Hiroshima Hospital, Hiroshima, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nishimoto
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yuki
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Sasaki
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Imada
authors.forename: Tarou
authors.initials: T
authors.lastname: Murakami
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Kodama
mesh_terms: D003937:Diagnosis, Differential; D004388:Dura Mater / Q000473:pathology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*; D012886:Skull