[Isolation and elucidation of chemical constituents of Shandanshaoyao Decoction(I)].
OBJECTIVE
To study the chemical constituents of Shandanshaoyao Decoction.


METHODS
The sample was prepared using boiling water, then precipitated by 75% ethanol. The ethanol soluble fraction was extracted by chloroform, ethyl acetate and n-butanol respectively. The extracts were isolated using silica gel and polyamide column chromatography, and the chemical constituents were identified by chemical and spectroscopic methods.


RESULTS
Six compounds were isolated from the chloroform and ethyl acetate extracts, and elucidated as tanshinone IIA, benzoic acid, ferulic acid, cryptotanshinone, beta-stitosterol and ursolic acid respectively.


CONCLUSIONS
A preliminary study on the chemical constituents in traditional Chinese compound recipe Shandanshaoyao Decoction is reported.
Wen
Z M
ZM
Institute of Materia Medica, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100050, China.
Xu
L X
LX
D045784:Abietanes; D027825:Crataegus / Q000737:chemistry; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D000960:Hypolipidemic Agents / Q000737:chemistry*; D029596:Paeonia / Q000737:chemistry; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D027561:Salvia miltiorrhiza / Q000737:chemistry; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D000097245:Ursolic Acid
D045784:Abietanes; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D000960:Hypolipidemic Agents; D010616:Phenanthrenes; D012855:Sitosterols; D014315:Triterpenes; D000097245:Ursolic Acid; C021751:tanshinone; C037886:cryptotanshinone; C025473:gamma-sitosterol