title: Efficacy of oral minocycline and hyperthermic treatment in a case of atypical mycobacterial skin infection by Mycobacterium marinum.
abstract: We report a case of atypical mycobacterial dermal infection caused by M. marinum, which was effectively treated with oral administration of minocycline and local hyperthermic treatment using chemical pocket warmers. A daily oral dose of 200 mg of minocycline was given, and local hyperthermic treatment was applied every evening for 5-6 hours with a disposable chemical pocket warmer. After 2.5 months of therapy, the lesion healed completely with scar formation. At 24 months after the completion of treatments, there is no sign of recurrence.
authors.affiliation: Department of Dermatology, Juntendo University School of Medicine, Hongo, Tokyo, Japan.
authors.forename: Katsuya
authors.initials: K
authors.lastname: Hisamichi
authors.forename: Masataro
authors.initials: M
authors.lastname: Hiruma
authors.forename: Masashi
authors.initials: M
authors.lastname: Yamazaki
authors.forename: Akiko
authors.initials: A
authors.lastname: Matsushita
authors.forename: Hideoki
authors.initials: H
authors.lastname: Ogawa
mesh_terms: D000284:Administration, Oral; D000328:Adult; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005500:Follow-Up Studies; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D008911:Minocycline / Q000008:administration & dosage*; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000628:therapy*; D009170:Nontuberculous Mycobacteria / Q000302:isolation & purification*; D017192:Skin Diseases, Bacterial / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D008911:Minocycline