title: [Expression of ET of early ischemic myocardium in rats].
abstract: To study the expression of ET of early ischemic myocardium, we designed a model of early myocardial ischemia (EMI) in rats. The study was conducted with SABC method and HE staining. Cardiac myocytes of ischemia showed a little ET-positive at 60-min. Cardiac myocytes, endothelium and smooth muscle of vessel showed ET-positive staining in the area of EMI after 120-min. Staining was negative for Ischemia myocardium at 30-min and for the control group. No change was seen with HE staining in all groups. The data indicates that ET-SABC method may reveal the injury of myocardial ischemia 60-min and longer and may provide a new marker to diagnose EMI in forensic pathology.
authors.affiliation: Sun Yat-sen University of Medical Sciences, GuangZhou 510089, PRC.
authors.forename: M
authors.initials: M
authors.lastname: Ma
authors.forename: X
authors.initials: X
authors.lastname: Xu
authors.forename: B
authors.initials: B
authors.lastname: Luo
authors.forename: X
authors.initials: X
authors.lastname: Wu
authors.forename: J
authors.initials: J
authors.lastname: Zhu
mesh_terms: D000818:Animals; D016232:Endothelins / Q000096:biosynthesis*; D007150:Immunohistochemistry; D009131:Muscle, Smooth, Vascular / Q000378:metabolism; D017202:Myocardial Ischemia / Q000378:metabolism* / Q000473:pathology; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
chemical_list: D016232:Endothelins