The high-pathogenicity island is absent in human pathogens of Salmonella enterica subspecies I but present in isolates of subspecies III and VI.
In this study we tested 74 Salmonella strains of all eight Salmonella groups and were able to demonstrate the presence of two high-pathogenicity island types in strains of Salmonella groups IIIa, IIIb, and VI. Most high-pathogenicity island-positive isolates produced yersiniabactin under iron-limited conditions and were positive for the high-molecular-weight proteins HMWP1 and HMWP2.
Oelschlaeger
T A
TA
Institut für Molekulare Infektionsbiologie, University of Würzburg, Roentgenring 11, D-97070 Würzburg, Germany.
Zhang
D
D
Schubert
S
S
Carniel
E
E
Rabsch
W
W
Karch
H
H
Hacker
J
J
D024509:3' Flanking Region; D024506:5' Flanking Region; D006801:Humans; D019779:Salmonella enterica / Q000145:classification* / Q000235:genetics / Q000472:pathogenicity*; D014774:Virulence / Q000235:genetics*