title: [Determination of eleven preservatives including bronopol in cosmetic by reversed-phase ion-pair chromatography].
abstract: Reversed-phase ion-pair chromatography was used to detect 11 preservatives including bronopol, esters of p-hydroxybenzoic acid (PHBA) in cosmetics. Zorbax C8 column was used and mobile phase was V (0.05 mol/L NaH2PO4):V(methyl alcohol):V(acetonitrile) = 50:35:15 with addition of hexadecyltrimethylammonium chloride (2 mmol/L) and the pH adjusted to 3.5 by using phosphoric acid. The wavelength 254 nm was selected for detection. Samples were extracted with methanol by ultrasonic method. The recoveries were 85%-107% and the relative standard deviations were 2.2%-7.5%.
authors.affiliation: Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021, China.
authors.forename: J
authors.initials: J
authors.lastname: Hu
authors.forename: J
authors.initials: J
authors.lastname: Wang
mesh_terms: D000891:Anti-Infective Agents, Local / Q000032:analysis; D019817:Benzoic Acid / Q000032:analysis; D019905:Benzyl Alcohol / Q000032:analysis; D002852:Chromatography, Ion Exchange / Q000379:methods*; D003358:Cosmetics / Q000737:chemistry*; D007202:Indicators and Reagents; D011310:Preservatives, Pharmaceutical / Q000032:analysis*; D011409:Propylene Glycols / Q000032:analysis*; D013844:Thiazoles / Q000032:analysis
chemical_list: D000891:Anti-Infective Agents, Local; D003358:Cosmetics; D007202:Indicators and Reagents; D011310:Preservatives, Pharmaceutical; D011409:Propylene Glycols; D013844:Thiazoles; C037057:Kathon 886; C006827:bronopol; D019817:Benzoic Acid; D019905:Benzyl Alcohol