Opioid-induced hyperalgesia: abnormal or normal pain?
Simonnet
Guy
G
Laboratoire Homéostasie-Allostasie-Pathologie, Université Victor-Ségalen Bordeaux 2, France. gsimonnet@yahoo.com
Rivat
Cyril
C
D000222:Adaptation, Physiological; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D002415:Cats; D004305:Dose-Response Relationship, Drug; D004361:Drug Tolerance / Q000502:physiology; D006801:Humans; D006930:Hyperalgesia / Q000139:chemically induced*; D008959:Models, Neurological; D009292:Narcotic Antagonists / Q000494:pharmacology; D009473:Neuronal Plasticity / Q000187:drug effects; D009479:Neuropeptides / Q000494:pharmacology; D009569:Nitric Oxide / Q000502:physiology; D010146:Pain / Q000503:physiopathology; D011493:Protein Kinase C / Q000502:physiology; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects / Q000502:physiology; D017450:Receptors, Opioid, mu / Q000187:drug effects / Q000502:physiology; D013375:Substance Withdrawal Syndrome / Q000209:etiology / Q000503:physiopathology
D000701:Analgesics, Opioid; D009292:Narcotic Antagonists; D009479:Neuropeptides; D016194:Receptors, N-Methyl-D-Aspartate; D017450:Receptors, Opioid, mu; D009569:Nitric Oxide; C087857:protein kinase C gamma; D011493:Protein Kinase C