[Study on expression of the glycoprotein in myocardial cell membrane of the rat's early myocardial ischemic].
OBJECTIVE
To explore expression of the glycoprotein in early myocardial ischemic.


METHODS
The glycoprotein changes occurred at the early acute cardiac ischemic area induced experimentally by ligation of left coronary artery of 32 SD rats. 6 lectins were measured by means of immunohistochemical methods.


RESULTS
Positive staining of PNA could be observed in ischemic area at 5 min after ischemia, and the positive area increased with the prolongation of ischemic period. It became the strongest for 2 h and then decreased.


CONCLUSIONS
This experiment proved that myocardial cell membrane in ischemia expressed D-galactose. This may be of some value in forensic medicine practice.
Li
Z H
ZH
Department of Forensic Medicine, Sun Yat-sen University of Medical Sciences, Guangzhou 510089. lizhhu@gzsums.edu.cn
Jing
H L
HL
Wang
D L
DL
D000818:Animals; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D008562:Membrane Glycoproteins / Q000096:biosynthesis*; D017202:Myocardial Ischemia / Q000378:metabolism*; D009206:Myocardium / Q000166:cytology / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley
D008562:Membrane Glycoproteins