BEPITOPE: predicting the location of continuous epitopes and patterns in proteins.
In growing need of obtaining highly specific monoclonal antibodies against novel proteins, we developed new functions implemented in the program BEPITOPE to predict continuous protein epitopes. This program not only can compute, combine, display and print prediction profiles, but also provides a list of suggested linear peptides to be synthesized. Novel facilities incorporated in BEPITOPE include the treatment of a whole genome, the search for a user-defined pattern, and the combination of prediction to pattern profiles. This latter approach is useful to remove unwanted predictions such as those including glycosylation sites.
Odorico
Michael
M
CEA Valrhô-Centre de Marcoule, DSV/DIEP/SBTN, BP17171, 30207 Bagnols sur Cèze, France.
Pellequer
Jean-Luc
JL
D000911:Antibodies, Monoclonal / Q000276:immunology / Q000378:metabolism; D000939:Epitopes; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000276:immunology*; D012984:Software
D000911:Antibodies, Monoclonal; D000939:Epitopes; D010455:Peptides; D011506:Proteins