title: Accumulation and loss of Lindane in the muscles, liver and brain of some freshwater fish after intoxication with gamacarbatox suspension.
abstract: Experiments were conducted under laboratory conditions on young specimens of Carassius carassius L., Cyprinus carpio L. and on adult specimens of Leucaspius delineatus Haeckel. The fish were subjected to a 30-day exposure to gamacarbatox suspension in a dose of 0.5 mg 1-1, containing 10% of lindane as active substance. Directly after the experiment on day 30, and then 40 and 50, lindane content was assessed in the muscles, liver and brain using the method of gas chromatography with an electron capture detector. In all the fish examined, the highest accumulation of lindane and its longest duration were observed in the brain. Less lindane was noted in the liver. The lowest level of lindane was found in the muscles and its concentration in that tissue decreased most rapidly.
authors.affiliation: Department of General Biology, Medical Academy of Białystok, Białystok, Poland.
authors.forename: Bozena
authors.initials: B
authors.lastname: Kiziewicz
authors.forename: Bazyli
authors.initials: B
authors.lastname: Czeczuga
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D004195:Disease Models, Animal; D005399:Fishes; D005618:Fresh Water; D001556:Hexachlorocyclohexane / Q000494:pharmacology / Q000633:toxicity*; D008099:Liver / Q000737:chemistry*; D009132:Muscles / Q000737:chemistry*; D011336:Probability; D012016:Reference Values; D018570:Risk Assessment; D013535:Suspensions; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D013535:Suspensions; D001556:Hexachlorocyclohexane