title: [Tracheal intubation in a case of idiopathic pulmonary fibrosis using remifentanil and propofol without muscle relaxants].
abstract: The anesthetic management of a 58 year-old-male suffering from idiopathic pulmonary fibrosis associated with a previous experience of altered dose-response relationship to muscle relaxants is reported. He underwent a gastroendoscopic surgical procedure. After intravenous atropine, remifentanil 3.0 microg kg(-1) was injected over 90 sec. Sixty seconds after the start of remifentanil bolus dose, propofol 2.0 mg kg(-1) was injected and intubation was performed 1 min after the administration of propofol. Anesthesia was maintained by N(2)O, oxygen, sevoflurane (0.5-0.8%) and remifentanil titrated infusion (mean dose of 0.15 mg kg(-1) min(-1)) under spontaneous respiration or assisted ventilation, if the patient was apnoic. The intubating conditions were good, a 30 per cent reduction in MAP was observed after propofol administration. The patient regained consciousness 5 minutes after the end of remifentanil administration and his trachea was extubated without any troubles. Recovery was uneventful without the need of long-term intensive therapy.
authors.affiliation: Dipartimento di Scienze Chirurgiche, Anestesiologiche, Rianimatorie e dell'Emergenza, Università degli Studi Federico II, Naples, Italy. tcafiero@tiscali.it
authors.forename: T
authors.initials: T
authors.lastname: Cafiero
authors.forename: R
authors.initials: R
authors.lastname: Burrelli
authors.forename: G
authors.initials: G
authors.lastname: Gargiulo
authors.forename: P
authors.initials: P
authors.lastname: Mastronardi
mesh_terms: D018686:Anesthetics, Intravenous; D016145:Endoscopy, Digestive System; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D010880:Piperidines; D015742:Propofol; D011658:Pulmonary Fibrosis / Q000150:complications*; D000077208:Remifentanil
chemical_list: D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil; D015742:Propofol