title: Heparin use during pregnancy.
abstract: The use of anticoagulants in pregnancy is problematic. In this focus, the authors reviewed the problems associated with the use of vitamin  K antagonist during pregnancy. Then, they presented the general considerations on the use of unfractioned heparin and low molecular weight heparin during pregnancy. Finally they established the therapeutic recommendations for anticoagulation during pregnancy including treatment and prophylaxis of venous thromboembolism, anticoagulation of pregnant women with mechanical heart valves and the management of pregnant women with antiphospholipid antibodies and multiple pregnancy losses.
authors.affiliation: Service de médecine interne, Hôpital La Rabta, Tunis.
authors.forename: Mohamed Habib
authors.initials: MH
authors.lastname: Houman
authors.forename: Imene
authors.initials: I
authors.lastname: Ksontini-Smida
authors.forename: Mohamed
authors.initials: M
authors.lastname: Miled
mesh_terms: D000026:Abortion, Habitual / Q000097:blood / Q000188:drug therapy; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000188:drug therapy; D016903:Drug Monitoring / Q000379:methods / Q000592:standards; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006493:Heparin / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods / Q000592:standards; D012307:Risk Factors; D013923:Thromboembolism / Q000097:blood / Q000188:drug therapy / Q000209:etiology
chemical_list: D000925:Anticoagulants; D006493:Heparin