title: Neurocysticercosis in children: clinical characteristics and outcome.
abstract: A study was undertaken on 176 children with neurocysticercosis to determine the clinical behaviour and long-term outcome of cases. The children were followed up prospectively in the paediatric neurology clinic for 6 years. Diagnosis was based primarily on CT scans. All the CT lesions were parenchymal and mostly single (87%) with ring enhancement and peri-lesional oedema. Partial seizure was the predominant presenting seizure type. About 65% of cases had recurrences at varying intervals during treatment. Albendazole therapy given to some cases did not appear to have any beneficial effect on seizure control. Repeat CTs done at varying intervals after the first seizures showed disappearance of the lesions in about 50% of cases. The majority of lesions disappeared without the use of albendazole. Recurrence of seizures after withdrawal of anti-epileptic medication was observed in 19% of the cases. Parenchymal neurocysticercosis in children commonly presents with partial seizures and ring lesions on CT. The disease can be managed well by anti-epileptic medication alone and the prognosis is good.
authors.affiliation: Department of Paediatrics, Maulana Azad Medical College, New Delhi-110002, India. btalukdar@rediffmail.com
authors.forename: Bibek
authors.initials: B
authors.lastname: Talukdar
authors.forename: Anurag
authors.initials: A
authors.lastname: Saxena
authors.forename: Vineet Kumar
authors.initials: VK
authors.lastname: Popli
authors.forename: Veena
authors.initials: V
authors.lastname: Choudhury
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D015766:Albendazole / Q000627:therapeutic use; D000923:Anticestodal Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D020019:Neurocysticercosis / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D011446:Prospective Studies; D012008:Recurrence; D012640:Seizures / Q000209:etiology; D017678:Sex Distribution; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000923:Anticestodal Agents; D000927:Anticonvulsants; D015766:Albendazole