[The single nucleotide polymorphisms and its application to forensic medicine].
Single-nucleotide polymorphisms (SNPs) are the most abundant forms of human genetic variation. These variable sites are present at high density in the genome, making them powerful tool for the diagnosis of genetic and genetic-related diseases, population genetics research and drug development. They are also found widespread application to the forensic medicine. This report mainly describe the SNPs characteristics and its potential applications to the forensic medicine including the possibility, the problems and high-throughput automation detection methods.
Hu
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Department of Forensic Medicine, Sun Yat-Sen University of Medical Sciences, GuangZhou 510080. hrgz@sohu.com
Wu
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D005554:Forensic Medicine; D006801:Humans; D020641:Polymorphism, Single Nucleotide