[Research of drug resistance and detection of methicillin-resistant Staphylococcus aureus in chronic maxillary sinusitis].
OBJECTIVE
To investigate the detection method of methicillin-resistant staphylococcus aureus (MRSA) in chronic maxillary sinusitis and the situation of drug resistance to some common antibiotics.


METHODS
Using multiplex polymerase chain reaction technique to detect the drug resistant gene (mecA) of MRSA and specific gene (femA) of staphylococcus aureus at the same time. Drug resistant tests were performed with disk diffusion (K-B) method.


RESULTS
femA is a specific gene of staphylococcus aureus, the detective ratio of mecA in MRSA is 96.2% (51/53). Vancomycin is the only antibiotic which is sensitive to MRSA, while others are not.


CONCLUSIONS
MRSA can be rapidly and specifically identified with multiplex PCR. There are drug resistance to many antibiotic drugs for MRSA.
Liu
F
F
Department of Otolaryngology, Changhai Hospital, Second Military Medical University, Shanghai 200433.
Zhou
S
S
Zhang
S
S
Deng
Q
Q
Zhang
L
L
Xu
Y
Y
Wang
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005798:Genes, Bacterial; D006801:Humans; D008297:Male; D015523:Maxillary Sinusitis / Q000382:microbiology*; D016106:Methicillin Resistance / Q000235:genetics*; D008875:Middle Aged; D013211:Staphylococcus aureus / Q000235:genetics*