title: Effect of lipid matrix and cytoskeleton proteins on Ca2+-activated K+ channels in erythrocytes of alcoholic and II type diabetes mellitus patients.
abstract: We studied the effect of changes in erythrocyte volume and irreversible thermal denaturation of cytoskeleton proteins and lipid matrix on activity of Ca(2+)-activated K+ channels in erythrocytes of alcoholic and patients with II type diabetes mellitus. Changes in Ca(2+)-dependent potassium permeability of erythrocyte membrane in alcoholic patients and patients with II type diabetes mellitus are related to modification of cytoskeleton, rather than to changes in lipid matrix.
authors.affiliation: Siberian State Medical University, Tomsk, Russia.
authors.forename: V D
authors.initials: VD
authors.lastname: Prokop'eva
authors.forename: I V
authors.initials: IV
authors.lastname: Petrova
authors.forename: A V
authors.initials: AV
authors.lastname: Sitozhevskii
authors.forename: S V
authors.initials: SV
authors.lastname: Kremeno
authors.forename: V I
authors.initials: VI
authors.lastname: Koryukin
authors.forename: M B
authors.initials: MB
authors.lastname: Baskakov
authors.forename: N A
authors.initials: NA
authors.lastname: Bokhan
authors.forename: V V
authors.initials: VV
authors.lastname: Novitskii
mesh_terms: D000437:Alcoholism / Q000097:blood*; D002118:Calcium / Q000097:blood*; D002463:Cell Membrane Permeability; D003598:Cytoskeletal Proteins / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000378:metabolism*; D004910:Erythrocyte Membrane / Q000378:metabolism; D004911:Erythrocyte Volume; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008055:Lipids / Q000097:blood*; D009994:Osmolar Concentration; D015221:Potassium Channels / Q000378:metabolism*; D011489:Protein Denaturation
chemical_list: D003598:Cytoskeletal Proteins; D008055:Lipids; D015221:Potassium Channels; D002118:Calcium