title: Patient-maintained sedation for oral surgery using a target-controlled infusion of propofol - a pilot study.
abstract: OBJECTIVE
  To assess the safety and efficacy of a new patient-maintained propofol system for conscious sedation in dentistry.
  
  
  METHODS
  Prospective clinical trial
  
  
  METHODS
  Department of Sedation, Glasgow Dental Hospital and School, 2001
  
  
  METHODS
  Patients scheduled for oral surgery with conscious sedation. Exclusions included ASA IV -V, inability to use the handset, opioid use and severe respiratory disease.
  
  
  METHODS
  Patients were given intravenous propofol to a level of 1.0 microg/ml (reducing from 1.5 microg/ml) using a target controlled infusion system, they then controlled their sedation level by double-clicking a handset which on each activation increased the propofol concentration by 0.2 microg/ml.
  
  
  METHODS
  Oxygen saturation, patient satisfaction, and surgeon satisfaction.
  
  
  RESULTS
  Twenty patients were recruited, 16 female and four male. Nineteen patients completed sedation and treatment successfully. Mean lowest oxygen saturation was 94%. No patients were over-sedated. All patients successfully used the system to maintain a level of sedation adequate for their comfort. Patient and surgeon satisfaction were consistently high.
  
  
  CONCLUSIONS
  Initial experience with this novel system has confirmed safety, patient satisfaction and surgeon satisfaction.
authors.affiliation: Glasgow Dental Hospital and School, Glasgow. leitch@bigfoot.com
authors.forename: J A
authors.initials: JA
authors.lastname: Leitch
authors.forename: N
authors.initials: N
authors.lastname: Sutcliffe
authors.forename: G N C
authors.initials: GN
authors.lastname: Kenny
mesh_terms: D000293:Adolescent; D000328:Adult; D016058:Analgesia, Patient-Controlled; D000766:Anesthesia, Dental; D002648:Child; D016292:Procedural Sedation; D003299:Cooperative Behavior; D003481:Cuspid / Q000601:surgery; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007260:Infusion Pumps; D008297:Male; D008875:Middle Aged; D008964:Molar, Third / Q000601:surgery; D019647:Oral Surgical Procedures; D010100:Oxygen / Q000097:blood; D017060:Patient Satisfaction; D010865:Pilot Projects; D015742:Propofol / Q000008:administration & dosage*; D011446:Prospective Studies; D012449:Safety; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D006993:Hypnotics and Sedatives; D010100:Oxygen; D015742:Propofol