title: Two cases of Aspergillus sinusitis with bone destruction.
abstract: We experienced the clinical courses of two cases of destructive Aspergillus in paranasal sinuses in which an Aspergillus fungus ball was formed, and which caused bony destruction are described. The case in which a nidus could not be completely surgically removed and with intervening diabetes had an unfavorable prognosis. It is recommend to perform an early expanded operation as well as to administer a sufficient amount of antifungal drugs for the treatment of destructive Aspergillus in paranasal sinuses.
authors.affiliation: Department of Otolaryngology, St. Marianna University School of Medicine, 2-16-1, Sugao, Miyamae-ku, 216-8511, Kawasaki city, Japan. s2miyabe@marianna-u.ac.jp
authors.forename: Satoshi
authors.initials: S
authors.lastname: Miyabe
authors.forename: Izumi
authors.initials: I
authors.lastname: Koizuka
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ochi
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kuroda
authors.forename: Mutsumi
authors.initials: M
authors.lastname: Kenmochi
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Okada
authors.forename: Hideo
authors.initials: H
authors.lastname: Tomisawa
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Sugiyama
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis* / Q000601:surgery; D003389:Cranial Nerve Diseases / Q000209:etiology; D018450:Disease Progression; D005005:Ethmoid Sinus / Q000473:pathology / Q000601:surgery; D015521:Ethmoid Sinusitis / Q000175:diagnosis* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery; D015523:Maxillary Sinusitis / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D009915:Orbit / Q000473:pathology / Q000601:surgery; D012008:Recurrence; D012086:Reoperation; D013101:Sphenoid Sinus / Q000473:pathology / Q000601:surgery; D015524:Sphenoid Sinusitis / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D015725:Fluconazole