[Evaluation of ventricular synchronization by fourier phase analysis in a radionuclide ventriculography].
BACKGROUND
Radionuclide ventriculography (RNV) evaluates segmental and global ventricular contractility and also detects conduction abnormalities.


OBJECTIVE
To assess the temporal parameters of ventricular synchronization in the normal heart by a third harmonic (3H) Fourier phase analysis in a RNV and introduce this technique in our center.


METHODS
Thirty normal subjects (19 men and 11 women) were included. An equilibrium RNV was performed in 35 degree left anterior oblique projection with 10 degree caudal tilt. The onset (T0); mean time (T(m)); total contraction time (T(t)); final time (T(f)) and propagation time (T(p)) for right (RV) and left ventricle (LV); as well as total propagation time (T(TP)); interventricular time (T(RV-LV)) and septum-lateral wall conduction time (T(S-LW)) were measured on the 3H Fourier histogram of the time-activity curve.


RESULTS
Right ventricle contraction started 5 ms before that of the left ventricle (T(0RV) = 66 +/- 38 ms; T(OLV) = 71 +/- 30 ms), with a longer total contraction time (T(tVD) = 67 +/- 28 ms vs T(tVI) = 64 +/- 38 ms). Total propagation time (T(TP)) was 69 +/- 37 ms and the interventricular time (T(RV-LV)) was 2 +/- 25 ms. Contraction progressed from septum to lateral wall, with a septum-lateral wall conduction time (T(S-LW)) of 4 +/- 22 ms.


CONCLUSIONS
Simultaneous contraction of right and left ventricles can be quantified by RNV phase analysis, providing a useful tool for ventricular resynchronization assessment in multisite pacing.
Peix
A
A
Instituto de Cardiología y Cirugía Cardiovascular, Sección de Nuclear Medicina Nuclear, La Habana, Cuba. peix@infomed.sld.cu
Ponce
F
F
Zayas
R
R
López
A
A
Cabrera
O
O
Dorticós
F
F
Maltas
A Ma
AM
Carrillo
R
R
D005260:Female; D005583:Fourier Analysis; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D015635:Radionuclide Ventriculography; D016276:Ventricular Function / Q000502:physiology*