title: A novel mutation in the gene for canine acid beta-galactosidase that causes GM1-gangliosidosis in Shiba dogs.
abstract: A homozygous recessive mutation, causing GM1-gangliosidosis in Shiba dogs, was identified as a deletion of C nucleotide 1668 in the gene for canine acid beta-galactosidase, which was a novel mutation in canine GM1-gangliosidosis.
authors.affiliation: Laboratory of Internal Medicine, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan. osam@vetmed.hokudai.ac.jp
authors.forename: O
authors.initials: O
authors.lastname: Yamato
authors.forename: D
authors.initials: D
authors.lastname: Endoh
authors.forename: A
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Masuoka
authors.forename: M
authors.initials: M
authors.lastname: Yonemura
authors.forename: A
authors.initials: A
authors.lastname: Hatakeyama
authors.forename: H
authors.initials: H
authors.lastname: Satoh
authors.forename: M
authors.initials: M
authors.lastname: Tajima
authors.forename: M
authors.initials: M
authors.lastname: Yamasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Maede
mesh_terms: D000818:Animals; D018076:DNA, Complementary / Q000235:genetics; D004283:Dog Diseases / Q000201:enzymology* / Q000235:genetics*; D004285:Dogs; D016537:Gangliosidosis, GM1 / Q000235:genetics* / Q000662:veterinary*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D001616:beta-Galactosidase / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; D001616:beta-Galactosidase