[Effects of diclofenac sodium combined with dionine in cases with fibrinous membrane after intraocular lens implantation].
OBJECTIVE
The effects of diclofenac sodium(DFNa) combined with dionine in cases with fibrin exudation membrane on intraocular lens (IOL) were studied.


METHODS
Thirty-two eyes, derived from sixteen adult pure bred New Zealand rabbits, were divided at random into two groups after extracapsular lens extraction with posterior chamber IOL implantation: (1) rabbits received DFNa eyedrops combined with dionine eyedrops; (2) rabbits received Pred forte eyedrops. The sum of fibrinous exudation membrane on IOL was observed on 1, 3, 5, 7, 14, 21, 30d postoperation.


RESULTS
The fibrin exudations in the DFNa combined with dionine group is less than the pred forte group (P > 0.05).


CONCLUSIONS
DFNa combined with dionine is effective in treating fibrin exudation membrane after extracapsular lens extraction and IOL implantation, and it is more effective than the pred forte.
Jia
S B
SB
Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha 410011, China.
Tang
L S
LS
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use; D004008:Diclofenac / Q000494:pharmacology* / Q000627:therapeutic use; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005036:Ethylmorphine / Q000494:pharmacology* / Q000627:therapeutic use; D005122:Exudates and Transudates; D005337:Fibrin; D019654:Lens Implantation, Intraocular / Q000009:adverse effects*; D008297:Male; D008566:Membranes; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000517:prevention & control*; D011817:Rabbits; D011897:Random Allocation
D000894:Anti-Inflammatory Agents, Non-Steroidal; D009883:Ophthalmic Solutions; D004008:Diclofenac; D005337:Fibrin; D005036:Ethylmorphine