[Influence of magnetic field on nitric oxide in hypothalamus and its relation to hypothalamic neuroendocrine nuclei].
By employing nitric acid reductase-spectrophotometry and NADPH-diaphorase/AVP cytochemistry technique, the effects of magnetic field on NO in hypothalamus and relations to Paraventricular Nucleus (PVN), Periventricular Nucleus (PEN), Supraoptic Nucleus (SON) and Suprachiasmatic Nucleus (SCN) were investigated. It was found that the NADPH-d positive neurons and some NADPH-d/AVP dually stained neurons existed in PVN, PEN, SON, but not in SCN, and the magnetic field induced NO (OD) increase there and the high NO (OD) level lasted for 3 hours. The results suggested that NO (OD) increase after the treatment of magnetic field in hypothalamus may result from strong expression of NOergic neurons in the PVN, PEN and SON. The coexistance of NO and AVP may play important role in the regulation of endocrine and neuroendocrine by the magnetic field.
Luo
Z G
ZG
Life Science Institute, Shenzhen University, Shenzhen 518060.
Han
Q G
QG
Zhang
X Y
XY
D000818:Animals; D004574:Electromagnetic Fields; D006651:Histocytochemistry; D007031:Hypothalamus / Q000378:metabolism*; D007032:Hypothalamus, Anterior / Q000378:metabolism* / Q000502:physiology; D008297:Male; D009252:NADPH Dehydrogenase / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013053:Spectrophotometry; D014667:Vasopressins / Q000378:metabolism
D014667:Vasopressins; D009569:Nitric Oxide; D009252:NADPH Dehydrogenase