title: [PCR-based DNA analysis of vWA31A, TH01, F13A01, FESFPS, TPOX and CSF1PO].
abstract: The allele and genotype frequencies of 6 tetranucleotide STR loci were investigated in a sample of 132 unrelated individuals from Chinese Han population. The PCR products were analyzed on 6% denaturing PAGE and detected using fluorescently labeled primers in an automated 377 sequencer(PE). All loci meet Hardy-Weinberg equilibrium. There was no random association of alleles among the 6 loci. The allele frequencies were compared with other population databases. Except locus vWA31A, the observed heterozygosity at other 5 loci was significantly lower than that reported in Caucasian and Black population studies. The calculated DP = 0.99999, PE = 0.9708, pM = 1.059 x 10(-5). The allelic frequency data can be used in forensic identification and paternity testing.
authors.affiliation: Department of Forensic Science, Sun Yat-sen University of Medical Science, Guangzhou 510089, P. R. China.
authors.forename: B
authors.initials: B
authors.lastname: Jiang
authors.forename: J Y
authors.initials: JY
authors.lastname: Guo
authors.forename: S Q
authors.initials: SQ
authors.lastname: Liang
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics; D004247:DNA / Q000032:analysis*; D005554:Forensic Medicine; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D016133:Polymerase Chain Reaction; D020080:Tandem Repeat Sequences
chemical_list: D004247:DNA