title: Spin trapping of superoxide in the presence of beta-cyclodextrins.
abstract: The trapping of superoxide anion with DMPO and DEPMPO has been carried out in the presence of a methylated beta-cyclodextrin, Me-beta-CD; inclusion of the spin adducts in the cavity of Me-beta-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascrobate anion in the case of DEPMPO.
authors.affiliation: UMR 6517 CNRS and Universités d'Aix-Marseille 1 and 3, Faculté des Sciences de Saint Jérôme, 13397 Marseille, France. hakim@srepir1.univ-mrs.fr
authors.forename: Hakim
authors.initials: H
authors.lastname: Karoui
authors.forename: Antal
authors.initials: A
authors.lastname: Rockenbauer
authors.forename: Sylvie
authors.initials: S
authors.lastname: Pietri
authors.forename: Paul
authors.initials: P
authors.lastname: Tordo
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D013113:Spin Labels; D019097:Spin Trapping; D013481:Superoxides / Q000737:chemistry*; D047392:beta-Cyclodextrins
chemical_list: D003505:Cyclodextrins; D013113:Spin Labels; D047392:beta-Cyclodextrins; D013481:Superoxides; C031215:betadex