title: [Interleukin-6 levels in the gingival crevicular fluid before and after periodontal treatment].
abstract: OBJECTIVE
  The aim of this study therefore is to determine if periodontal scaling and root planning could affect the IL-6 level in the GCF of teeth with periodontitis.
  
  
  METHODS
  12 teeth from 12 patients with severe periodontitis were clinically examined and sampled before therapy. 2 weeks after the periodontal scaling and root planning, the same 12 teeth were examined and sampled again. The IL-6 levels in GCF were detected using ELISA method. There are some evidences that the interleukin-6 (IL-6) levels in the periodontal tissue and gingival crevicular fluid (GCF) of periodontitis sites are significantly higher than that of healthy periodontal sites.
  
  
  RESULTS
  The IL-6 levels in GCF from the teeth declined and the periodontal clinical indices of these teeth also apparently dropped down.
  
  
  CONCLUSIONS
  Periodontal treatment, including periodontal scaling and root planning could affect the IL-6 levels in GCF of teeth with periodontitis.
authors.affiliation: College of Stomatology, West China University of Medical Sciences.
authors.forename: Y
authors.initials: Y
authors.lastname: Wu
authors.forename: C
authors.initials: C
authors.lastname: Zhao
authors.forename: J
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000328:Adult; D012534:Dental Scaling; D005260:Female; D005883:Gingival Crevicular Fluid / Q000378:metabolism*; D006801:Humans; D015850:Interleukin-6 / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000628:therapy*; D013357:Subgingival Curettage
chemical_list: D015850:Interleukin-6