Rapid molecular theranostics in infectious diseases.
The increasing availability of rapid and sensitive nucleic acid testing assays for infectious diseases will revolutionize the practice of medicine by gradually reducing the need for standard culture-based microbiological methods that take at least two days. Molecular theranostics in infectious diseases is an emerging concept in which molecular biology tools are used to provide rapid and accurate diagnostic assays to enable better initial management of patients and more efficient use of antimicrobials. Essential conditions and the quality control required for the development and validation of such molecular theranostic assays are reviewed.
Picard
François J
FJ
Centre de Recherche en Infectiologie de l'Université Laval, Centre Hospitalier Universitaire de Québec, Pavillon CHUL, 2705 Boulevard Laurier, Québec, Canada, G1V 4G2.
Bergeron
Michel G
MG
D000818:Animals; D001419:Bacteria / Q000737:chemistry / Q000235:genetics; D003141:Communicable Diseases / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods* / Q000639:trends; D009696:Nucleic Acids / Q000302:isolation & purification; D014780:Viruses / Q000737:chemistry / Q000235:genetics
D009696:Nucleic Acids