Efficient ring-opening reaction of epoxides and aziridines promoted by tributylphosphine in water.
Tributylphosphine was found to be an effective promoting reagent for the ring-opening reaction of various epoxides and aziridines with nucleophile to produce corresponding anti-bifunctional products in moderate to excellent yields in water.
Fan
Ren-Hua
RH
Shanghai-Hong Kong Joint Laboratory in Chemical Synthesis, State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China.
Hou
Xue-Long
XL