title: Surgical treatment of chronic intestinal pseudo-obstruction: report of three cases.
abstract: We report the cases of three patients with chronic intestinal pseudo-obstruction (CIP) whose quality of life (QOL) was improved by palliative surgery in combination with home parenteral nutrition (HPN). Loop enterostomy and shortening of the gastrointestinal tract was performed with good results in all three patients to relieve abdominal distension that was progressive despite treatment with prokinetic drugs. Oral intake was also improved after surgical treatment in one patient who underwent massive resection of the jejunoileum. HPN maintained a satisfactory nutritional state in all patients. These three case reports serve to demonstrate that surgical intervention to improve QOL should be considered for patients with CIP if medication is not effective and symptoms are progressive.
authors.affiliation: Division of Biological Regulation and Oncology, Department of Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
authors.forename: Chikashi
authors.initials: C
authors.lastname: Shibata
authors.forename: Hiroo
authors.initials: H
authors.lastname: Naito
authors.forename: Yuji
authors.initials: Y
authors.lastname: Funayama
authors.forename: Kouhei
authors.initials: K
authors.lastname: Fukushima
authors.forename: Akihiko
authors.initials: A
authors.lastname: Hashimoto
authors.forename: Taku
authors.initials: T
authors.lastname: Kitayama
authors.forename: Munenori
authors.initials: M
authors.lastname: Nagao
authors.forename: Seiki
authors.initials: S
authors.lastname: Matsuno
authors.forename: Iwao
authors.initials: I
authors.lastname: Sasaki
mesh_terms: D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D004032:Diet; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D011788:Quality of Life; D016896:Treatment Outcome