title: Synthesis and insecticidal activity of novel N-oxydihydropyrroles: 4-hydroxy-3-mesityl-1-methoxymethoxy derivatives with various substituents at the 5-position.
abstract: This paper reports the synthesis and insecticidal activity of a series of novel 4-hydroxy-3-mesityl-1-methoxymethoxy-1,5-dihydro-2H-pyrrol-2-one derivatives, in which the substituents at the 5-position were varied with a number of alkyl and spirocycloalkyl groups. Investigation of the structure-activity relationships revealed that small alkyl and spirocyclohexyl groups had a favorable effect on the insecticidal activity of these agents against Myzus persicae.
authors.affiliation: Agroscience Research Laboratories, Sankyo Co., Ltd., 1041 Yasu, Yasu-cho, Yasu-gun, Shiga 520-2342, Japan. mtitou@shina.sankyo.co.jp
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Ito
authors.forename: Hideshi
authors.initials: H
authors.lastname: Okui
authors.forename: Harumi
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Shigeru
authors.initials: S
authors.lastname: Mio
authors.forename: Ayako
authors.initials: A
authors.lastname: Kinoshita
authors.forename: Takashi
authors.initials: T
authors.lastname: Obayashi
authors.forename: Takako
authors.initials: T
authors.lastname: Miura
authors.forename: Junko
authors.initials: J
authors.lastname: Nagai
authors.forename: Shinji
authors.initials: S
authors.lastname: Yokoi
authors.forename: Reiji
authors.initials: R
authors.lastname: Ichinose
authors.forename: Keiji
authors.initials: K
authors.lastname: Tanaka
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Kodama
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Iwasaki
authors.forename: Takaaki
authors.initials: T
authors.lastname: Miyake
authors.forename: Miho
authors.initials: M
authors.lastname: Takashio
authors.forename: Jun
authors.initials: J
authors.lastname: Iwabuchi
mesh_terms: D000818:Animals; D001042:Aphids; D001937:Brassica; D018553:Cucumis sativus; D006540:Herbicides / Q000633:toxicity; D007202:Indicators and Reagents; D007306:Insecticides / Q000138:chemical synthesis* / Q000633:toxicity*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000633:toxicity*; D013329:Structure-Activity Relationship
chemical_list: D006540:Herbicides; D007202:Indicators and Reagents; D007306:Insecticides; D011758:Pyrroles