title: A long-term experience with the Cabrol root replacement technique for the management of ascending aortic aneurysms and dissections.
abstract: BACKGROUND
  Little information exists regarding the long-term results of the Cabrol technique. This study aimed at exploring, over a 16-year period, the results of aortic root replacements employing this procedure.
  
  
  METHODS
  Between 1986 and 2002 forty-five patients (mean age 58.7 +/- 13.8 years old, 84.4% male) underwent a Cabrol procedure. Aortic dissection was the most frequent cause of aortic disease in this series (n = 17), followed by annuloaortic ectasia (n = 10), atherosclerotic aneurysm (n = 5) and poststenotic dilatation (n = 5). Six patients (13.4%) had undergone a previous aortic operation, 8 (17.7%) had a Marfan syndrome and five (11.1%) underwent concomitant arch replacement. Mean clinical follow-up was 87.3 +/- 24.3 months. Twenty-eight patients (93.3% of survivors) had a transesophageal echocardiography (TEE) performed at a mean of 64 +/- 32 months postoperatively.
  
  
  RESULTS
  Early mortality was 20%. It was 9.1% for patients with an ascending aortic aneurysm and 41.2% for dissections (p = 0.026). Independent multivariate predictors of early mortality were: aortic dissection (p = 0.009), emergency operation (p < 0.001), operative year (p = 0.02), cross-clamp time (p = 0.001), and CPB duration (p < 0.001). Actuarial survival was 0.77 +/- 0.06, 0.72 +/- 0.06, 0.59 +/- 0.04 and 0.59 +/- 0.04 at 1, 5, 10, and 16 years, respectively. Multivariate analysis revealed age (p = 0.007), cross-clamp time (p = 0.0006) and CPB duration (p = 0.009) as strong predictors of poor late survival. A periprosthetic jet with significant valve regurgitation was detected by TEE in 3 patients. In one of them, an infected periprosthetic space-right ventricular fistula was demonstrated requiring reoperation. Altogether, freedom from reoperation and endocarditis at 16 years was 0.97 +/- 0.02 and 0.94 +/- 0.03, respectively.
  
  
  CONCLUSIONS
  The Cabrol technique demonstrated a nonnegligible incidence of early and long-term complications. It should be rarely used and only when a "button" technique is not feasible.
authors.affiliation: Department of Cardiovascular Sciences, Ospedale S. Maria Della Misericordia, Udine, Italy. sandrogelsomino@virgilio.it
authors.forename: Sandro
authors.initials: S
authors.lastname: Gelsomino
authors.forename: Romeo
authors.initials: R
authors.lastname: Frassani
authors.forename: Paolo
authors.initials: P
authors.lastname: Da Col
authors.forename: Giorgio
authors.initials: G
authors.lastname: Morocutti
authors.forename: Gianluca
authors.initials: G
authors.lastname: Masullo
authors.forename: Leonardo
authors.initials: L
authors.lastname: Spedicato
authors.forename: Ugolino
authors.initials: U
authors.lastname: Livi
mesh_terms: D000784:Aortic Dissection / Q000401:mortality / Q000601:surgery*; D001011:Aorta / Q000601:surgery; D001014:Aortic Aneurysm / Q000401:mortality / Q000601:surgery*; D017548:Echocardiography, Transesophageal; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D015999:Multivariate Analysis; D012086:Reoperation; D015996:Survival Rate