[Influence of mobile phase composition on chiral separation of organic selenium racemates].
The chiral separation of some chiral compounds with similar structure on the cellulose tris (3,5-dimethylphenylcarbamate) chiral stationary phase prepared by us was obtained. Ternary mobile phases influencing chiral recognition were investigated. A mode of interaction between the structural character of samples and chiral stationary phase is discussed. The results indicated that the retention and chiral separation of the analytes had a bigger change with minute addition of alcohols or acetonitrile as modifier in n-hexane/2-propanol (80/20, volume ratio) binary mobile phase.
Han
Xiao-qian
XQ
Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Qi
Bang-feng
BF
Dun
Hui-juan
HJ
Zhu
Xin-yi
XY
Na
Peng-jun
PJ
Jiang
Sheng-xiang
SX
Chen
Li-ren
LR
D019840:2-Propanol; D002219:Carbamates; D002482:Cellulose / Q000031:analogs & derivatives*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D006586:Hexanes; D016566:Organoselenium Compounds / Q000302:isolation & purification*; D048448:Phenylcarbamates; D013237:Stereoisomerism
D002219:Carbamates; D006586:Hexanes; D016566:Organoselenium Compounds; D048448:Phenylcarbamates; C065943:cellulose tris-3,5-dimethylphenyl-carbamate; C026385:n-hexane; D002482:Cellulose; D019840:2-Propanol