title: Environmental allergens and asthma in urban elementary schools.
abstract: BACKGROUND
  Asthma in school children is rising, and indoor allergens are very common triggers of asthma attacks; however, the risk of the school environment on asthma has not been well studied.
  
  
  OBJECTIVE
  To determine the presence and the levels of common aeroallergens in schools, where asthma prevalence rates are high.
  
  
  METHODS
  Settled dust samples were collected from 12 Baltimore City public elementary schools, and they were analyzed for the following allergens: cockroaches (Bla g 1/2), dust mites (Der f 1/p 1), dog (Can f 1), cat (Fel d 1), and mouse (Mus m 1). School asthma prevalence rates were correlated with allergen levels, and association between allergen levels and other risk factors present in the schools' environment was examined.
  
  
  RESULTS
  The mean and range levels were 1.49 U/g (0 to 8) for Bla g 1/2; 0.38 microg/g (0 to 11.9) for the Der f 1/p 1; 1.44 microg/g (0.1 to 9.6) for Can f 1; 1.66 microg/g (0.2 to 12) for Fel d 1; and 6.24 microg/g (0.3 to 118.3) for Mus m 1. Dust mite, cat and dog allergens were significantly in rooms with carpet and/or area rugs, compared to rooms with bare floors (P < 0.05). Asthma prevalence rates varied from 11.8 to 20.8% between schools and positively correlation with the mean levels of Bla g 1/2 in the schools (P = 0.001).
  
  
  CONCLUSIONS
  Common allergens that are known to trigger asthma were detected in all school environments, where asthma prevalence rates were high. However, the overall allergen levels were low, indicating that other factors, including exposures in the homes of asthmatic patients, may have more relevance to sensitization and symptoms than school exposures.
authors.affiliation: Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. samr@epi.umaryland.edu
authors.forename: Sania
authors.initials: S
authors.lastname: Amr
authors.forename: Mary E
authors.initials: ME
authors.lastname: Bollinger
authors.forename: Monica
authors.initials: M
authors.lastname: Myers
authors.forename: Robert G
authors.initials: RG
authors.lastname: Hamilton
authors.forename: Sheila R
authors.initials: SR
authors.lastname: Weiss
authors.forename: Maura
authors.initials: M
authors.lastname: Rossman
authors.forename: Lisette
authors.initials: L
authors.lastname: Osborne
authors.forename: Sidey
authors.initials: S
authors.lastname: Timmins
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Kimes
authors.forename: Elissa R
authors.initials: ER
authors.lastname: Levine
authors.forename: Carol J
authors.initials: CJ
authors.lastname: Blaisdell
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D000485:Allergens / Q000009:adverse effects* / Q000032:analysis; D000818:Animals; D039741:Antigens, Dermatophagoides / Q000009:adverse effects / Q000032:analysis; D052179:Antigens, Plant; D060829:Arthropod Proteins; D016282:Aspartic Acid Endopeptidases / Q000009:adverse effects / Q000032:analysis; D001249:Asthma / Q000453:epidemiology / Q000209:etiology*; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D003058:Cockroaches; D003546:Cysteine Endopeptidases; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D006023:Glycoproteins / Q000009:adverse effects / Q000032:analysis; D006801:Humans; D008396:Maryland / Q000453:epidemiology; D051379:Mice; D015995:Prevalence; D012572:School Health Services / Q000706:statistics & numerical data*; D013223:Statistics as Topic; D014504:Urban Health / Q000706:statistics & numerical data*
chemical_list: D000393:Air Pollutants; D000485:Allergens; D039741:Antigens, Dermatophagoides; D052179:Antigens, Plant; D060829:Arthropod Proteins; D006023:Glycoproteins; C105482:allergen Bla g 1; C091462:allergen Can f I; D003546:Cysteine Endopeptidases; C451159:Dermatophagoides farinae antigen f 1; C451162:Dermatophagoides pteronyssinus antigen p 1; D016282:Aspartic Acid Endopeptidases; C094699:allergen Bla g 2; C059296:Fel d 1 protein, Felis domesticus