[Biology and pathobiology of death receptors in liver].
Death receptors induce apoptosis by intracellular signaling transmission and relate to body growth, development, disease and death. This paper reviews the structural character of death receptors, and the mechanisms by which apoptosis is induced. The biology and pathobiology of these death receptors in liver are discussed as well.
Liu
Zhimin
Z
Surgical Laboratory, West China Hospital of Sichuan University, Chengdu 610041.
Chen
Junjie
J
D017209:Apoptosis / Q000502:physiology*; D058851:GPI-Linked Proteins; D006801:Humans; D008099:Liver / Q000473:pathology / Q000502:physiology*; D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand; D018124:Receptors, Tumor Necrosis Factor / Q000502:physiology*; D053320:Receptors, Tumor Necrosis Factor, Member 10c; D053319:Tumor Necrosis Factor Decoy Receptors; D019014:fas Receptor / Q000502:physiology*
D058851:GPI-Linked Proteins; D053220:Receptors, TNF-Related Apoptosis-Inducing Ligand; D018124:Receptors, Tumor Necrosis Factor; D053320:Receptors, Tumor Necrosis Factor, Member 10c; C105190:TNFRSF10A protein, human; C505639:TNFRSF10B protein, human; C108661:TNFRSF10C protein, human; D053319:Tumor Necrosis Factor Decoy Receptors; D019014:fas Receptor