[Role of phospholipase D in phagocytosis and exocytosis].
Mammalian phospholipase D(PLD) is a very important enzyme in the cellular signalling pathways. More and more lines of evidences suggest that PLD may be pivotal on multiple specialized steps in receptor-mediated phagocytosis and exocytosis. In this review, we will explore the recent advances on the role and the mechanism of PLD in phagocytosis and exocytosis.
Lu
Y B
YB
Department of Pharmacology, Medical School of Zhejiang University, Hangzhou 310031.
Zhou
H L
HL
D000818:Animals; D005089:Exocytosis / Q000502:physiology*; D006801:Humans; D010587:Phagocytosis / Q000502:physiology*; D010739:Phospholipase D / Q000378:metabolism / Q000502:physiology*; D011971:Receptors, Immunologic / Q000502:physiology*
D011971:Receptors, Immunologic; C028495:phagocytosis receptor; D010739:Phospholipase D