[The determination of cantharidin in AIDI liquid injection by gas chromatography].
A method for the determination of cantharidin in AIDI liquid injection with gas chromatography is described. The cantharidin was extracted with dichloromethane and then determined by gas chromatography with OV-17 packed column and FID detector. Its distribution constant between dichloromethane and water was 480. The extraction recoveries of cantharidin were 99%-102%. The calibration curve was Y = -113 + 35,900X, r = 0.9999 and the detection limit was 0.02 mg/L in liquid injection. As the results showed, the method is simple, rapid, sensitive and precise for determining cantharidin in AIDI liquid injection.
Fang
Y
Y
Department of Chemistry, Guizhou Normal University, Guiyang 550001, China.
Zhang
M S
MS
D000970:Antineoplastic Agents / Q000032:analysis; D002193:Cantharidin / Q000032:analysis*; D002849:Chromatography, Gas; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D012680:Sensitivity and Specificity
D000970:Antineoplastic Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D002193:Cantharidin