title: Malignant fibrous histiocytoma of scalp with intracranial invasion 20 years after postoperative irradiation.
abstract: We report a case of malignant fibrous histiocytoma with intracranial invasion occurring 20 years after radiation therapy for astrocytoma. Magnetic resonance imaging suggested that a dumbbell-shaped tumor arising from soft tissue was pressing the brain. Histopathological findings revealed a storiform pattern with spindle cells such as fibroblasts, histiocytes, epithelioid cells with irregularly shaped nuclei, and bizarre giant cells. Three operations involving craniectomy were necessary because of recurrence.
authors.affiliation: Department of Dermatology, Hyogo Prefectural Tsukaguchi Hospital, Hyogo, Japan.
authors.forename: Junji
authors.initials: J
authors.lastname: Hayami
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kurokawa
authors.forename: Kenji
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Kusumoto
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000532:radiotherapy / Q000601:surgery; D001932:Brain Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D002467:Cell Nucleus / Q000648:ultrastructure; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000601:surgery; D006644:Histiocytes / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D012535:Scalp / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D012888:Skull Neoplasms / Q000473:pathology* / Q000601:surgery