Neo-clerodane diterpenoids from Croton schiedeanus.
Two new neo-clerodane type furano diterpenoids were isolated from the aerial part of Croton schiedeanus, besides the clerodane diterpenes cis- and trans-dehydrocrotonin, previously isolated from other species of Croton. Structural elucidation was achieved on basis of extensive NMR experiments, including X-ray diffraction analysis and molecular mechanics calculations. The previously known flavonoids ayanin and quercetin-3,7-dimethyl ether were also obtained from the extract of this plant.
Puebla
Pilar
P
Departamento de Química Farmacéutica, Facultad de Farmacia, E-37007, Salamanca, Spain. puebla@usal.es
López
Jose L
JL
Guerrero
Mario
M
Carrón
Rosalía
R
Martín
M Luisa
ML
San Román
Luis
L
San Feliciano
Arturo
A
D003105:Colombia; D029802:Croton / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D013237:Stereoisomerism; D014961:X-Ray Diffraction
C472936:12-hydroxycascarillone; C472935:5-hydroxydehydrocrotonin; D004224:Diterpenes; D045785:Diterpenes, Clerodane; D005663:Furans; C103060:dehydrocrotonin