[Determination of sulfacetamide sodium and sulfanilamide in shao tang ling ointment by high performance liquid chromatography].
An HPLC method for the determination of sulfacetamide sodium and sulfanilamide in Shao Tang Ling ointment was developed. The chromatographic conditions were: column, Spherisorb C18, mobile phase, methanol-0.25% (V/V)-acetic acid solution (7:93); detector UV-257 nm. The average recoveries were 98.9% (n = 5), RSD = 0.64% for sulfacetamide sodium and 99.3% (n = 5), RSD = 1.58% for sulfanilamide. The analytical method is simple, quick, accurate and reproducible.
Xu
S
S
Fujian Provincial Institute for Drug Control, Fuzhou, 350001.
Wu
L
L
D002056:Burns / Q000188:drug therapy; D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D009824:Ointments / Q000032:analysis; D013409:Sulfacetamide / Q000032:analysis*; D000077145:Sulfanilamide; D013424:Sulfanilamides / Q000032:analysis*
D004338:Drug Combinations; D009824:Ointments; D013424:Sulfanilamides; D000077145:Sulfanilamide; D013409:Sulfacetamide