title: Atopic dermatitis.
abstract: Atopic dermatitis is a highly pruritic chronic inflammatory skin disorder affecting 10-20% of children worldwide. Symptoms can persist or begin in adulthood. It is also the most common cause of occupational skin disease in adults. This disease results from an interaction between susceptibility genes, the host's environment, pharmacological abnormalities, skin barrier defects, and immunological factors. New management approaches have evolved from advances in our understanding of the pathobiology of this common skin disorder.
authors.affiliation: Division of Pediatric Allergy and Immunology, National Jewish Medical and Research Center, Denver, CO 80206, USA. leungd@njc.org
authors.forename: Donald Y M
authors.initials: DY
authors.lastname: Leung
authors.forename: Thomas
authors.initials: T
authors.lastname: Bieber
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002648:Child; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D003937:Diagnosis, Differential; D005512:Food Hypersensitivity; D005938:Glucocorticoids; D006801:Humans; D015995:Prevalence
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids