title: Essential hypertension: antecedents in children.
abstract: A prospective study was conducted to determine the incidence of essential hypertension (EH) and identify markers, if any, in children of essential hypertension families. The study group included 90 children (2-18 years) with a parent or grandparent with EH while the control group had 25 age matched children from non-hypertensive families. Around 30% children (n=27) from these families had a diastolic blood pressure of >95th centile and an additional 27% (n=24) had borderline hypertension. The serum cholesterol, serum triglycerides and 24 hour urinary sodium excretion were significantly higher in the study group (p < 0.05) as compared to controls. The children from the study group also had a significant high salt (p < 0.001) and fat intake (P < 0.05).
authors.affiliation: Department of Pediatrics, T.N.M.C. Nair Hospital, Mumbai-400 008, India.
authors.forename: Surekha
authors.initials: S
authors.lastname: Joshi
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Gupta
authors.forename: Sonali
authors.initials: S
authors.lastname: Tank
authors.forename: Sushma
authors.initials: S
authors.lastname: Malik
authors.forename: D S
authors.initials: DS
authors.lastname: Salgaonkar
mesh_terms: D000293:Adolescent; D001795:Blood Pressure Determination; D015992:Body Mass Index; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000453:epidemiology / Q000378:metabolism; D015994:Incidence; D007194:India / Q000453:epidemiology; D010375:Pedigree; D011446:Prospective Studies; D012964:Sodium / Q000652:urine; D012982:Sodium, Dietary / Q000008:administration & dosage; D014280:Triglycerides / Q000097:blood
chemical_list: D012982:Sodium, Dietary; D014280:Triglycerides; D002784:Cholesterol; D012964:Sodium