title: Opioid "holiday" following antagonist supported detoxification during general anesthesia improves opioid agonist response in a cancer patient with opioid addiction.
authors.affiliation: Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen, Germany. christa.breitfeld@uni-essen.de
authors.forename: Christa
authors.initials: C
authors.lastname: Breitfeld
authors.forename: Matthias
authors.initials: M
authors.lastname: Eikermann
authors.forename: Peter
authors.initials: P
authors.lastname: Kienbaum
authors.forename: Jürgen
authors.initials: J
authors.lastname: Peters
mesh_terms: D015360:Analgesia, Epidural; D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000627:therapeutic use*; D000768:Anesthesia, General; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000150:complications / Q000601:surgery; D002045:Bupivacaine / Q000008:administration & dosage / Q000627:therapeutic use; D002813:Chondrosarcoma / Q000150:complications / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D009293:Opioid-Related Disorders / Q000150:complications* / Q000503:physiopathology; D010148:Intractable Pain / Q000150:complications* / Q000188:drug therapy
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D008691:Methadone; D002045:Bupivacaine