Comparative study of Saccharomyces cerevisiae LPS.
LPS of yeast strains producing human epidermal growth factor were studied. Experiments demonstrated the absence of essential differences in the characteristics of these LPS and LPS of nonrecombinant Saccharomyces cerevisiae strains, which allowed us to develop a universal complex technology of simultaneous preparation of heterologous proteins and highly active immunomodulating LPS.
Gordonova
I K
IK
Research, Training, and Methodological Center of Biomedical Technologies, All-Russian Institute of Medicinal and Aromatic Plants, Moscow, Russia.
Nikitina
Z K
ZK
Bykov
V A
VA
D000818:Animals; D007963:Leukocytes, Mononuclear / Q000187:drug effects; D008070:Lipopolysaccharides / Q000737:chemistry* / Q000494:pharmacology / Q000633:toxicity; D051379:Mice; D011994:Recombinant Proteins / Q000737:chemistry / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000145:classification / Q000235:genetics / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry* / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism
D008070:Lipopolysaccharides; D011994:Recombinant Proteins; D029701:Saccharomyces cerevisiae Proteins