title: Analysis of 'SHENMAI' injection by HPLC/MS/MS.
abstract: An HPLC/MS/MS method was developed for the analysis of 'SHENMAI' injection, composed of red ginseng and ophiopogon. The constituents of 'SHENMAI' were found to be similar with those of ginseng and 39 ginsenosides were detected. By the studies of MS and MS/MS spectra and the comparison with literature data, most of these ginsenosides were identified. Based on this study, suggestions were put forward to improve the quality control system of 'SHENMAI' injection.
authors.affiliation: Institute of Pharmaceutical Engineering, College of Materials Science and Chemical Engineering, Zhejiang University, Hangzhou 310027, PR China.
authors.forename: Zhang
authors.initials: Z
authors.lastname: Haijiang
authors.forename: Wu
authors.initials: W
authors.lastname: Yongjiang
authors.forename: Cheng
authors.initials: C
authors.lastname: Yiyu
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D007202:Indicators and Reagents; D013058:Mass Spectrometry; D031441:Ophiopogon / Q000737:chemistry*; D005894:Panax / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis*; D012997:Solvents; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D007202:Indicators and Reagents; D010936:Plant Extracts; D012997:Solvents; C009252:fructus schizandrae, radix ginseng, radix ophiopogonis drug combination