Neuroleptic malignant syndrome: uncommon postoperative diagnostic dilemma.
Neuroleptic malignant syndrome occurred in a 71-year-old man on haloperidol therapy for mild depressive dementia. After coronary artery bypass grafting, he developed hyperthermia, elevated creatine kinase without a corresponding rise in the MB-isoenzyme, leukocytosis, raised liver enzymes, urea, and creatinine. His condition responded to bromocriptine therapy.
Bhan
Suraj
S
Department of Anaesthesia, Escorts Heart Institute and Research Centre, Okhla Road, New Delhi 110025, India.
Kulkarni
Vinay
V
Mehta
Yatin
Y
Sharma
Krishan Kant
KK
Trehan
Naresh
N
Suri
Madan Lal
ML
D000368:Aged; D001971:Bromocriptine / Q000627:therapeutic use; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D003324:Coronary Artery Disease / Q000601:surgery*; D003704:Dementia / Q000188:drug therapy; D003937:Diagnosis, Differential; D018491:Dopamine Agonists / Q000627:therapeutic use; D018492:Dopamine Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D006220:Haloperidol / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D011183:Postoperative Complications
D018491:Dopamine Agonists; D018492:Dopamine Antagonists; D001971:Bromocriptine; D006220:Haloperidol