title: [Intrathecal morphine for postoperative analgesia in cardiac surgery].
abstract: OBJECTIVE
  The aim of study was to evaluate features for spinal morphine in undergoing coronary artery bypass surgery in early postoperative time and side effects of opioids.
  
  
  METHODS
  Two groups of patients undergoing coronary artery bypass surgery were analyzed. In first group (15 patients) spinal morphine 2 mg and general anesthesia was used, control group (22 patients) - just general anesthesia. Postoperative pain was analyzed with VAS (Visual Analogical Scale). For analgesia, after surgery, was used piritramide via i/v in both groups. Dose of piritramide, extubation time and side effects was analysed after surgery.
  
  
  RESULTS
  In first group dose of piritramide was 4.5+/-1.1 mg, in control group - 16.5+/-1.1 mg (p<0.05). Extubation time in both groups (354+/-36 min. and 279+/-17 min.) and side effects (nausea and vomiting) was similar.
  
  
  CONCLUSIONS
  Spinal morphine decreased pain after cardiosurgery and don't increased extubation time and side effects of opioids.
authors.affiliation: Clinic of Cardiac Surgery, Kaunas University of Medicine Hospital, Eiveniu 2, 3007 Kaunas, Lithuania.
authors.forename: Tadas
authors.initials: T
authors.lastname: Lenkutis
authors.forename: Algimantas
authors.initials: A
authors.lastname: Bieliūnas
authors.forename: Irmina
authors.initials: I
authors.lastname: Gedminaite
mesh_terms: D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000627:therapeutic use; D000768:Anesthesia, General; D001026:Coronary Artery Bypass; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage* / Q000627:therapeutic use; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000517:prevention & control*; D010892:Pirinitramide / Q000008:administration & dosage* / Q000627:therapeutic use; D011182:Postoperative Care
chemical_list: D000701:Analgesics, Opioid; D010892:Pirinitramide; D009020:Morphine