[Animal experiment of the ketamine effects on traumatic brain injury resulting from impact maxillofacial injury].
OBJECTIVE
To test the effects of ketamine (KET) on traumatic brain injury resulting from impact maxillofacial injury.


METHODS
The rat models with middle serious traumatic brain injury were obtained by falling impaction at maxillofacial region of the rats, then the animals were treated with KET in the early stage, and the alteration of the neural function in those rats was observed at the same time.


RESULTS
There was obvious difference between the rats in the KET-treating groups and the control group. It took about 2 days fewer than that of the control group for rats in the KET-treating group to recover.


CONCLUSIONS
KET can shorten the recovery time of rats with brain injury resulting from impact maxillofacial injury.
Zhang
C
C
Department of Stomatology, Southwest Hospital, Third Military Medical University.
Li
H
H
Liao
W
W
Yang
J
J
Shi
W
W
D000818:Animals; D001930:Brain Injuries / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D005260:Female; D007649:Ketamine / Q000627:therapeutic use*; D008297:Male; D008446:Maxillofacial Injuries / Q000150:complications* / Q000188:drug therapy; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
D018696:Neuroprotective Agents; D007649:Ketamine