[Peculiarities of the structure of the speech-motor cortex of the brain frontal lobe in a deaf-mute child].
The aim of present investigation was the study of the cytoarchitecture of the motor-speech areas 44 and 45 of the brain cortex of a 4-year-old deaf-mute child. We have also compared cytoarchitecture of the motor-speech zone of the brain cortex in a deaf-mute child with the same brain region in a normal child of a similar age. Series of 20 mm-thick frontal sections stained with cresyl violet were studied using morphometric methods. Our data indicate the significant anomalies of both the brain gross structure and cytoarchitecture of the motor-speech zone of the brain cortex in a deaf-mute child. Considerable decrease in the values of neuronal profile area in layers III3 and V and in satellite gliocyte density was observed while the neuro-glial ratios were changed. Our results certify that development of child's brain is disturbed in conditions of speech dysfunction and auditory deficiency.
Bogolepova
I N
IN
Laboratory of Brain Anatomy and Architectonics, RAMS Scientific Research Institute of Brain, Moscow.
Malofeeva
L I
LI
Belogrud'
T V
TV
D001921:Brain / Q000033:anatomy & histology / Q000473:pathology; D002675:Child, Preschool; D003638:Deafness / Q000473:pathology* / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology*; D005625:Frontal Lobe / Q000033:anatomy & histology / Q000166:cytology / Q000473:pathology*; D006801:Humans; D007223:Infant; D009044:Motor Cortex / Q000033:anatomy & histology / Q000166:cytology / Q000473:pathology*; D009457:Neuroglia / Q000166:cytology / Q000473:pathology; D009474:Neurons / Q000166:cytology / Q000473:pathology; D009929:Organ Size