title: Tau and Alzheimer's disease: the long road to anti-tangle therapeutics.
authors.affiliation: The Institute for the Study of Aging, New York, NY, USA.
authors.forename: Howard M
authors.initials: HM
authors.lastname: Fillit
authors.forename: Lorenzo M
authors.initials: LM
authors.lastname: Refolo
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000378:metabolism; D000818:Animals; D003226:Congresses as Topic; D004195:Disease Models, Animal; D020536:Enzyme Activators / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D016874:Neurofibrillary Tangles / Q000187:drug effects / Q000378:metabolism*; D010749:Phosphoprotein Phosphatases / Q000187:drug effects / Q000378:metabolism; D010766:Phosphorylation / Q000187:drug effects; D010770:Phosphotransferases / Q000037:antagonists & inhibitors / Q000378:metabolism; D011485:Protein Binding / Q000187:drug effects; D016875:tau Proteins / Q000378:metabolism*
chemical_list: D016229:Amyloid beta-Peptides; D020536:Enzyme Activators; D004791:Enzyme Inhibitors; D016875:tau Proteins; D010770:Phosphotransferases; D010749:Phosphoprotein Phosphatases