title: [Neural and hemodynamic mechanisms of neurogenic pulmonary edema].
abstract: Acute pulmonary edema has been reported in man and animals with intracranial disorders, head trauma or cerebral compression. In anesthetized rats, cerebral compression produced acute, fulminating and fatal lung injury. Intense activation of the sympathetic mechanism in the brain stem induced systemic hypertension and a series of hemodynamic changes. Pulmonary volume loading was the result of drastic decrease in aortic flow accompanying a decline in pulmonary arterial flow. The acute increase in pulmonary blood volume caused severe rises in pulmonary arterial and venous pressures leading to disruption of lung vessels.
authors.affiliation: Department of Physiology and of Neurosurgery, Tzu Chi College of Medicine and Humanities, Hualien 970.
authors.forename: H I
authors.initials: HI
authors.lastname: Chen
authors.forename: C F
authors.initials: CF
authors.lastname: Su
authors.forename: C Y
authors.initials: CY
authors.lastname: Chai
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000150:complications / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications / Q000503:physiopathology; D011654:Pulmonary Edema / Q000209:etiology / Q000503:physiopathology*; D013564:Sympathetic Nervous System / Q000503:physiopathology*