title: Immunostimulating reconstituted influenza virosomes.
abstract: Immunostimulating reconstituted influenza virosomes (IRIVs) are a liposomal carrier system. Influenza hemagglutinin and neuraminidase are intercalated into the lipid bilayer and give the IRIVs their fusogenic activity. The system is already registered for human use and allows a specific targetting of antigens to a cellular or a humoral immune response. IRIVs are able to deliver proteins, RNA/DNA, peptides and mimetics to immunocompetent cells.
authors.affiliation: Pevion Biotech Ltd, Rehhagstrasse 79, Bern 3018, Switzerland. rinaldo.zurbriggen@pevion.com
authors.forename: Rinaldo
authors.initials: R
authors.lastname: Zurbriggen
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage*; D008081:Liposomes; D008854:Microscopy, Electron; D013601:T-Lymphocytes / Q000276:immunology; D022701:Virosomes / Q000008:administration & dosage*
chemical_list: D000276:Adjuvants, Immunologic; D007252:Influenza Vaccines; D008081:Liposomes; D022701:Virosomes