title: Postmenopausal frontal fibrosing alopecia.
abstract: Recently a new entity, postmenopausal frontal fibrosing alopecia, was added to the established subtypes of scarring alopecias affecting postmenopausal women. This condition is characterized by a progressive frontal hairline recession associated with scarring. We studied the clinical and histopathologic features in four women with this disorder. Of note, a history of bilateral oophorectomy in two of them appears to be a new association. All four cases had frontoparietal recession of the hairline and two of them also had loss of their eyebrows. None of our four patients had any mucous membrane or other skin lesions. Histological examination showed perifollicular fibrosis and lymphocytic inflammation around the isthmus and infundibular areas of the follicles. No effective treatments have emerged for this type of postmenopausal alopecia, but progression of the hair loss and scarring appears to be self-limiting. We believe that this condition is a distinct clinicopathological variant of lichen planopilaris.
authors.affiliation: Department of Dermatology, University Hospital La Paz, Madrid, Spain. juanmagc@hotmail.com
authors.forename: E
authors.initials: E
authors.lastname: Naz
authors.forename: C
authors.initials: C
authors.lastname: Vidaurrázaga
authors.forename: N
authors.initials: N
authors.lastname: Hernández-Cano
authors.forename: P
authors.initials: P
authors.lastname: Herranz
authors.forename: M
authors.initials: M
authors.lastname: Mayor
authors.forename: M
authors.initials: M
authors.lastname: Hervella
authors.forename: M
authors.initials: M
authors.lastname: Casado
mesh_terms: D000328:Adult; D000368:Aged; D000505:Alopecia / Q000188:drug therapy / Q000473:pathology*; D001706:Biopsy; D005260:Female; D005355:Fibrosis / Q000473:pathology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D017698:Postmenopause; D012535:Scalp / Q000473:pathology
chemical_list: D005938:Glucocorticoids