[Value of interleukin-8 determination in diagnosis of benign and malignant breast tumor].
The studies were performed in women with breast carcinoma, benign breast tumour and in a control group. Serum levels of IL-8 were determined 1-2 days before surgical procedure, according to the enzyme-linked immunosorbent assay (ELISA). Pretreatment levels of IL-8 were significantly increased in carcinoma patients in relation to the benign tumour and the control group. The frequency of increased results and absolute values of IL-8 levels showed tendency to significant increase with the stage of disease. These results suggested that IL-8 measurement may be useful in estimation of disease progression in women with breast carcinoma.
Zakrzewska
Irena
I
Zakład Laboratoryjnej Diagnostyki Klinicznej AM w Białymstoku.
Kozłowski
Leszek
L
Wojtukiewicz
Marek
M
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000276:immunology* / Q000473:pathology; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005348:Fibrocystic Breast Disease / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D016209:Interleukin-8 / Q000097:blood*; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D013997:Time Factors
D014408:Biomarkers, Tumor; D016209:Interleukin-8