Challenges and opportunities in evaluating diagnostic tests.
The field of clinical research conducted to evaluate diagnostic tests has evolved substantially over the last 25 years. This article discusses three current challenges and opportunities in conducting such research: the limitations of the "traditional focus" of clinical epidemiology in evaluating tests; how different decision makers use data produced by clinical epidemiology research, and what those uses mean for future research; and special challenges and opportunities in evaluating molecular-based tests.
Ransohoff
David F
DF
University of North Carolina at Chapel Hill, CB #7080 724 Burnett-Womack, Chapel Hill, NC 27599-7080, USA. ransohof@med.unc.edu
D003933:Diagnosis; D004813:Epidemiology / Q000639:trends; D005069:Evaluation Studies as Topic; D005544:Forecasting; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity