title: Surgery in severe factor XIII deficiency: report of a case of epilepsy neurosurgery and review.
abstract: Factor XIII (FXIII) deficiency is a rare autosomal recessive congenital disorder of haemostasis, associated with a high risk of intracranial haemorrhage. Intracranial haemorrhage can result in neurological sequelae including seizure disorders. In some cases, medically intractable epilepsy led to epilepsy surgery. Little has been reported on the management of FXIII deficiency during surgery, and there is only a few data on the management, safety and efficacy of epilepsy surgery in the patients with haemostatic disorder. We report here an epilepsy neurosurgery in a case of severe FXIII deficiency.
authors.affiliation: Haemostasis Unit, CHL1, Grendale, France. gpernod@chu-grenoble.fr
authors.forename: G
authors.initials: G
authors.lastname: Pernod
authors.forename: C
authors.initials: C
authors.lastname: Barro
authors.forename: B
authors.initials: B
authors.lastname: Arnutti
authors.forename: F
authors.initials: F
authors.lastname: Blanc-Jouvan
authors.forename: S
authors.initials: S
authors.lastname: Garrel
authors.forename: P
authors.initials: P
authors.lastname: Kahn
authors.forename: L
authors.initials: L
authors.lastname: Minotti
authors.forename: A
authors.initials: A
authors.lastname: Koudsie
authors.forename: A L
authors.initials: AL
authors.lastname: Benabid
authors.forename: I
authors.initials: I
authors.lastname: Wrobleski
authors.forename: A
authors.initials: A
authors.lastname: Joannard
authors.forename: B
authors.initials: B
authors.lastname: Polack
mesh_terms: D002675:Child, Preschool; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D005176:Factor XIII / Q000627:therapeutic use*; D005177:Factor XIII Deficiency / Q000150:complications* / Q000188:drug therapy; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures
chemical_list: D005176:Factor XIII