title: Diffusion magnetic resonance imaging in infantile neuroaxonal dystrophy.
abstract: A 7-month-old girl with infantile neuroaxonal dystrophy is reported. In diffusion MRI, the pyramidal tracts and dentate nuclei had high signal on b = 1,000 s/mm2 images and low apparent diffusion coefficient (ADC) values. This pattern likely reflected the presence of abnormal (dystrophic) axons with restricted mobility of water molecules. A reverse pattern was evident in the cerebellar cortex with high ADC values. This was likely a reflection of dysmyelination or lack of myelination.
authors.affiliation: Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey. rnsener@hotmail.com
authors.forename: R Nuri
authors.initials: RN
authors.lastname: Sener
mesh_terms: D001921:Brain / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007223:Infant; D019150:Neuroaxonal Dystrophies / Q000175:diagnosis*