A case of lymphomatoid papulosis with prominent myxoid change resembling a mesenchymal neoplasm.
Lymphomatoid papulosis is a chronic recurrent eruption of self-regressing papules and nodules. Histologically this disorder is characterized by large atypical lymphoid cells resembling Reed-Sternberg (RS) cells that are set in a background of a mixed inflammatory infiltrate. Depending on the architecture of the infiltrate and the percentage of atypical cells, the histologic appearance is subclassified as type A, B, or C. The different histologic patterns do not seem to correlate with distinct clinical appearances. We report a case of lymphomatoid papulosis with unusual histologic features affecting a 14-year-old girl. The presence of anaplastic cells in a background of myxoid stroma closely resembled a sarcoma on histologic examination.
Atkins
Kristin A
KA
Department of Pathology, Stanford University Medical Center, California 94305-5302, USA.
Dahlem
Monica M
MM
Kohler
Sabine
S
D000293:Adolescent; D015703:Antigens, CD / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D017731:Lymphomatoid Papulosis / Q000378:metabolism / Q000473:pathology*; D008648:Mesoderm / Q000473:pathology; D012075:Remission, Spontaneous; D012509:Sarcoma / Q000473:pathology
D015703:Antigens, CD; D015415:Biomarkers