Two cases of Aspergillus sinusitis with bone destruction.
We experienced the clinical courses of two cases of destructive Aspergillus in paranasal sinuses in which an Aspergillus fungus ball was formed, and which caused bony destruction are described. The case in which a nidus could not be completely surgically removed and with intervening diabetes had an unfavorable prognosis. It is recommend to perform an early expanded operation as well as to administer a sufficient amount of antifungal drugs for the treatment of destructive Aspergillus in paranasal sinuses.
Miyabe
Satoshi
S
Department of Otolaryngology, St. Marianna University School of Medicine, 2-16-1, Sugao, Miyamae-ku, 216-8511, Kawasaki city, Japan. s2miyabe@marianna-u.ac.jp
Koizuka
Izumi
I
Ochi
Kentaro
K
Tanaka
Kenjiro
K
Kuroda
Hisashi
H
Kenmochi
Mutsumi
M
Okada
Tomoyuki
T
Tomisawa
Hideo
H
Sugiyama
Yutaka
Y
D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis* / Q000601:surgery; D003389:Cranial Nerve Diseases / Q000209:etiology; D018450:Disease Progression; D005005:Ethmoid Sinus / Q000473:pathology / Q000601:surgery; D015521:Ethmoid Sinusitis / Q000175:diagnosis* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery; D015523:Maxillary Sinusitis / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D009915:Orbit / Q000473:pathology / Q000601:surgery; D012008:Recurrence; D012086:Reoperation; D013101:Sphenoid Sinus / Q000473:pathology / Q000601:surgery; D015524:Sphenoid Sinusitis / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed
D015725:Fluconazole