title: [A convenient synthesis of retinal derivatives with a modified trimethylcyclohexene ring].
abstract: A method of simultaneous one-stage synthesis of three retinal derivatives (5,6-dioxo-5,6-seco-, 5,6-dihydro-5,6-epoxy-, and 4-oxoretinal) was proposed, with the yield of the first derivative being approximately 50%. These compounds are useful tools for studying the antitumor activity of retinoids, the reconstituted bacteriorhodopsin analogues with changed parameters of photocycle, and the reactivity of retinal derivatives in the processes of oxidation by molecular oxygen. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2002, vol. 28, no. 6; see also http://www.maik.ru.
authors.affiliation: Lomonosov State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 117571 Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Mironova
authors.forename: S V
authors.initials: SV
authors.lastname: Leont'eva
authors.forename: S V
authors.initials: SV
authors.lastname: Sheviakov
authors.forename: S G
authors.initials: SG
authors.lastname: Alekseeva
authors.forename: V I
authors.initials: VI
authors.lastname: Shvets
authors.forename: O V
authors.initials: OV
authors.lastname: Demina
authors.forename: I S
authors.initials: IS
authors.lastname: Krasnokutskaia
authors.forename: E I
authors.initials: EI
authors.lastname: Finkel'shteĭn
authors.forename: A A
authors.initials: AA
authors.lastname: Khodonov
mesh_terms: D003510:Cyclohexanes / Q000737:chemistry*; D004952:Esters / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D012172:Retinaldehyde / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D014212:Tretinoin / Q000737:chemistry
chemical_list: D003510:Cyclohexanes; D004952:Esters; D014212:Tretinoin; D012172:Retinaldehyde