title: [Experimental study on using diclofenac sodium or dionine topically to treat fibrinous membrane after intraocular lens implantation].
abstract: OBJECTIVE
  To find a reasonable method for treating and preventing fibrinous membrane after intraocular lens (IOL) implantation by using diclofenac sodium or dionine topically.
  
  
  METHODS
  Forty-eight eyes of twenty-four adult pure bred New Zealand rabbits were divided into three groups randomly. Group A: rabits received diclofenac sodium eyedrops; Group B: rabbits received dionine eyedrops; Group C: controlled. All the eyes received lens extraction combined with posterior chamber intraocular lens implantation. The fibrinous membrane was observed after 1, 3, 5, 7, 14, 21 and 30 days postoperatively.
  
  
  RESULTS
  The fibrinous membran in Group A was less than that of Group B and Group C, (P < 0.05); the difference between group B and group C on fibrinous membrance was also statistically significant (P < 0.05).
  
  
  CONCLUSIONS
  The study suggests that both diclofenac sodium and the dionine eyedrops can treat fibrinous membrane after IOL implantation. The effect of diclofenac sodium is better than that of dionine.
authors.affiliation: Department of Ophthalmology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
authors.forename: S B
authors.initials: SB
authors.lastname: Jia
authors.forename: L S
authors.initials: LS
authors.lastname: Tang
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use; D004008:Diclofenac / Q000494:pharmacology* / Q000627:therapeutic use; D004357:Drug Synergism; D005036:Ethylmorphine / Q000494:pharmacology* / Q000627:therapeutic use; D005122:Exudates and Transudates; D005260:Female; D005337:Fibrin; D019654:Lens Implantation, Intraocular / Q000009:adverse effects*; D008297:Male; D008566:Membranes; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000517:prevention & control*; D011817:Rabbits; D011897:Random Allocation
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009883:Ophthalmic Solutions; D004008:Diclofenac; D005337:Fibrin; D005036:Ethylmorphine