title: Neo-clerodane diterpenoids from Croton schiedeanus.
abstract: Two new neo-clerodane type furano diterpenoids were isolated from the aerial part of Croton schiedeanus, besides the clerodane diterpenes cis- and trans-dehydrocrotonin, previously isolated from other species of Croton. Structural elucidation was achieved on basis of extensive NMR experiments, including X-ray diffraction analysis and molecular mechanics calculations. The previously known flavonoids ayanin and quercetin-3,7-dimethyl ether were also obtained from the extract of this plant.
authors.affiliation: Departamento de Química Farmacéutica, Facultad de Farmacia, E-37007, Salamanca, Spain. puebla@usal.es
authors.forename: Pilar
authors.initials: P
authors.lastname: Puebla
authors.forename: Jose L
authors.initials: JL
authors.lastname: López
authors.forename: Mario
authors.initials: M
authors.lastname: Guerrero
authors.forename: Rosalía
authors.initials: R
authors.lastname: Carrón
authors.forename: M Luisa
authors.initials: ML
authors.lastname: Martín
authors.forename: Luis
authors.initials: L
authors.lastname: San Román
authors.forename: Arturo
authors.initials: A
authors.lastname: San Feliciano
mesh_terms: D003105:Colombia; D029802:Croton / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045785:Diterpenes, Clerodane; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: C472936:12-hydroxycascarillone; C472935:5-hydroxydehydrocrotonin; D004224:Diterpenes; D045785:Diterpenes, Clerodane; D005663:Furans; C103060:dehydrocrotonin