First total synthesis of the marine illudalane sesquiterpenoid alcyopterosin E.
The first synthesis of the marine illudalane sesquiterpenoid alcyopterosin E was accomplished through a concise ABC ring-formation strategy using a rhodium(I)-catalysed intramolecular alkyne cyclotrimerisation as key connection.
Witulski
Bernhard
B
Universität Kaiserslautern, Erwin-Schrödinger-Strasse, D-67663 Kaiserslautern, Germany. witulski@rhrk.uni-kl.de
Zimmermann
Axel
A
Gowans
Nicholas D
ND
D037421:Anthozoa / Q000737:chemistry; D003500:Cyclization; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism
D012717:Sesquiterpenes; C466487:alcyopterosin A; C471995:alcyopterosin E