title: [Local microcirculatory disorders in the cochlea basal turn near termination in guinea pigs].
abstract: OBJECTIVE
  To study the characteristics of hearing loss caused by local microcirculatory disorders in the cochlea basal turn near termination of guinea pigs.
  
  
  METHODS
  The local microcirculatory disorders in the cochlea basal turn near termination of guinea pigs were caused by photochemical reaction; morphological changes were observed by light microscope; the CAP N1 amplitude, CAP N1 latency and CAP N1 threshold shift which were evoked by short tone burst were recorded by Madsen 2250.
  
  
  RESULTS
  Morphological changes showed that histopathological changes were located in the basal turn near termination of cochlea. The CAP N1 amplitude, CAP N1 latency and CAP N1 threshold shift showed that the hearing loss was remarkable in the high-range frequencies.
  
  
  CONCLUSIONS
  If the local microcirculatory disorders in the cochlea basal turn near termination take place, the hearing losses are more remarkable in the high-range frequencies.
authors.affiliation: Department of Otolaryngology, Southwest Hospital, Third Military Medical University, Chongqing 400038.
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.forename: J
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D003051:Cochlea / Q000098:blood supply*; D006168:Guinea Pigs; D006311:Hearing Disorders / Q000209:etiology; D008833:Microcirculation / Q000503:physiopathology*