title: Experience with the Advanced Breast Biopsy Instrumentation (ABBI) system.
abstract: BACKGROUND
  The Advanced Breast Biopsy Instrumentation (ABBI) System is designed to excise nonpalpable breast lesions under stereotactic control. We report our experience with special regard to the histological evaluation of margins.
  
  
  METHODS
  Breast biopsies using the ABBI system were performed on 101 patients with microcalcifications. In histologically-proven breast cancer, a re-excision was performed.
  
  
  RESULTS
  Malignant lesions were found in thirteen patients (3 CLIS, 5 DCIS, 5 invasive ductal carcinoma). The margins were positive in two specimens with DCIS. In subsequent lumpectomies one patient with invasive cancer had residual intraductal cancer. All the patients with DCIS had residual cancer, even those with negative margins of the ABBI-specimen. Only minor complications were observed with the ABBI procedure.
  
  
  CONCLUSIONS
  The ABBI system is a safe, minimally invasive stereotactic breast biopsy technique. It saves open biopsies in atypical hyperplasia and CLIS. In cases of DCIS or invasive cancer re-excision is inevitable.
authors.affiliation: Department of Obstetrics and Gynecology, University Medical Center, Hugstetter Str. 55, D-79106 Freiburg, Germany.
authors.forename: Dirk Otto
authors.initials: DO
authors.lastname: Watermann
authors.forename: Almut
authors.initials: A
authors.lastname: Einert
authors.forename: Claudia
authors.initials: C
authors.lastname: Ehritt-Braun
authors.forename: Annette
authors.initials: A
authors.lastname: Hasenburg
authors.forename: Dirk Günter
authors.initials: DG
authors.lastname: Kieback
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000295:instrumentation / Q000379:methods*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D002278:Carcinoma in Situ / Q000473:pathology / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000601:surgery; D018275:Carcinoma, Lobular / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D013238:Stereotaxic Techniques / Q000295:instrumentation