title: Sebaceous carcinoma arising from nevus sebaceus: a case report.
abstract: BACKGROUND
  Sebaceous carcinoma (SC) is a rare, aggressive, malignant tumor that is derived from adnexal epithelium of sebaceous glands that are distributed mostly in the skin of the head, neck, and hair-bearing regions of the body.
  
  
  OBJECTIVE
  To discuss the clinical and histologic features and the prognosis of the extraocular SC.
  
  
  METHODS
  We report a case of SCs of the scalp arising from a previous lesion clinically compatible with a nevus sebaceous. The lesion was surgically excised completely.
  
  
  RESULTS
  The postoperative course was free of complications, and the patient was clinically free of disease at her recent follow-up 2 years after treatment.
  
  
  CONCLUSIONS
  The absence of metastasis or cutaneous recurrence in our patient, notwithstanding the size of the lesion and its late removal, almost 25 years after the first signs of its growth, confirms a much improved prognostic behavior for extraocular SCs.
authors.affiliation: Department of Dermatology, University of Florence, Florence, Italy. dermoncologia@tin.it
authors.forename: Vincenzo
authors.initials: V
authors.lastname: de Giorgi
authors.forename: Daniela
authors.initials: D
authors.lastname: Massi
authors.forename: Giovanna
authors.initials: G
authors.lastname: Brunasso
authors.forename: Francesca
authors.initials: F
authors.lastname: Mannone
authors.forename: H Peter
authors.initials: HP
authors.lastname: Soyer
authors.forename: Paolo
authors.initials: P
authors.lastname: Carli
mesh_terms: D000368:Aged; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D009506:Nevus / Q000150:complications / Q000473:pathology*; D012535:Scalp; D012626:Sebaceous Gland Neoplasms / Q000150:complications / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*; D016896:Treatment Outcome