The Xenopus arx gene is expressed in the developing rostral forebrain.
The human aristaless-related homeobox ( ARX) gene is mutated in several patients with X-linked mental retardation and/or other neurologic pathologies. We report the isolation and expression pattern of a Xenopus arx gene. Similar to other vertebrate arx genes, Xenopus arx is expressed in the developing telencephalon, diencephalon, and floor plate.
El-Hodiri
Heithem M
HM
Center for Molecular and Human Genetics, Children's Research Institute, 700 Children's Drive, Columbus, OH 43026, USA. ELH@pediatrics.ohio-state.edu
Qi
Xiu-Lan
XL
Seufert
Daniel W
DW
D000595:Amino Acid Sequence; D000818:Animals; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox; D018398:Homeodomain Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D016548:Prosencephalon / Q000196:embryology* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D014981:Xenopus / Q000235:genetics*
D018398:Homeodomain Proteins