title: [Analysis of penicillins in whole blood by reversed high-performance liquid chromatography].
abstract: A reversed-HPLC method was established to determinate penicillins in whole blood. Thiamphenicol as internal standard was added to 0.5 ml blood. Proteins in blood were precipitated with acetonitrile, then the separate supernatant was directly injected onto the chromatography column. The range of five penicillins' linearities was 0.9918 to 0.9996, their range of relative recovery was 91.75% to 107.33%, their CV was 3.56% to 9.85%. Effects of different storage temperatures on the stability of analytes and interference of other antibiotics were also studied.
authors.affiliation: Institute of Forensic Sciences, Ministry of Justice, Shanghai 200063, P. R. China.
authors.forename: W
authors.initials: W
authors.lastname: Liu
authors.forename: M
authors.initials: M
authors.lastname: Shen
authors.forename: X Y
authors.initials: XY
authors.lastname: Zhuo
authors.forename: J
authors.initials: J
authors.lastname: Bu
authors.forename: P
authors.initials: P
authors.lastname: Xiang
authors.forename: H J
authors.initials: HJ
authors.lastname: Wu
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Huang
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D010406:Penicillins / Q000097:blood*; D011817:Rabbits
chemical_list: D010406:Penicillins