title: [Determination of sildenafil in medicines for erectile dysfunction by capillary electrophoresis].
abstract: A method has been developed for the determination of sildenafil in the medicines for erectile dysfunction by capillary electrophoresis. The samples were analyzed with 60 mmol/L NaH2PO4(pH 5.0) running buffer at 35 degrees C capillary temperature and 30 kV voltage. A linear calibration was obtained from 0.07 g/L to 1.05 g/L of sildenafil (r = 0.9985) with the RSD of 4.7% for peak area, and the average recovery was 97.4%. The results were compared with those of HPLC, showing that the method is precise, simple and cost-effective, and can be used as a complementary method to HPLC.
authors.affiliation: College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
authors.forename: Run-kai
authors.initials: RK
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Bo
authors.forename: Hu-wei
authors.initials: HW
authors.lastname: Liu
authors.forename: Ke-an
authors.initials: KA
authors.lastname: Li
mesh_terms: D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D019587:Dietary Supplements / Q000032:analysis*; D019075:Electrophoresis, Capillary / Q000379:methods*; D007172:Erectile Dysfunction; D006801:Humans; D008297:Male; D010879:Piperazines / Q000032:analysis*; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones; D014665:Vasodilator Agents / Q000032:analysis
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate