Mycophenolate mofetil: new applications for this immunosuppressant.
OBJECTIVE
This article should familiarize the reader with the pharmacokinetics, mechanisms of action, potential toxicities, and current and future applications of mycophenolate mofetil.


METHODS
The current medical literature.


RESULTS
Mycophenolate mofetil is an immunosuppressive agent that has been used for transplant recipients. More recently, this agent has been used to treat several inflammatory conditions.


CONCLUSIONS
Mycophenolate mofetil has the potential to be a useful agent in the treatment of several inflammatory conditions, including systemic lupus erythematosus.
Moder
Kevin G
KG
Division of Rheumatology, Mayo Clinic, Rochester, Minnesota 55905, USA.
D001327:Autoimmune Diseases / Q000150:complications / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D005544:Forecasting; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D007249:Inflammation / Q000150:complications / Q000188:drug therapy; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives / Q000494:pharmacology* / Q000627:therapeutic use*; D012307:Risk Factors
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid