[Detection of S-100 protein in laryngeal carcinoma].
OBJECTIVE
To study the relationship between S-100 protein and prognosis of laryngeal carcinoma.


METHODS
S-100 protein was observed by immunohistochemical methods using anti-S-100 protein antibody in 68 laryngeal carcinoma and 21 non-cancer laryngeal tissues.


RESULTS
The result showed that S-100 protein positive were found 43 (63.24%) in 68 laryngeal carcinoma. S-100 protein positive cells were interspersed among the tumor cells and in the stroma. S-100 protein were rare in non-cancer laryngeal tissues. The five-year survival rate in patients with S-100 protein positive was significantly higher than that in patients with S-100 protein negative.


CONCLUSIONS
Our result indicated that the detection of S-100 protein is of value for the prognostic analysis in patients with laryngeal carcinoma.
Hu
S
S
Department of Otolaryngology, Sir Run Run Shaw Hospital, Medical Center of Zhejiang University, Hangzhou 310016.
Zhang
L
L
Wen
S
S
Li
D
D
D006801:Humans; D007822:Laryngeal Neoplasms / Q000737:chemistry* / Q000401:mortality; D011379:Prognosis; D009418:S100 Proteins / Q000032:analysis*; D015996:Survival Rate
D009418:S100 Proteins