title: Ceramic inlays for restoring posterior teeth.
abstract: BACKGROUND
  In recent decades ceramic inlays have been used with the increasing requirements from patients for tooth-coloured restorations in posterior teeth. Ceramic inlays can offer an excellent appearance, however, their long-term prognosis is uncertain, as only a few studies have reported the long-term clinical performance of these restorations.
  
  
  OBJECTIVE
  To compare the effectiveness of ceramic inlays in posterior teeth with other posterior restorations.
  
  
  METHODS
  We conducted an electronic search of the Cochrane Oral Health Group Trials Register, the Cochrane Central Register of Controlled Trials ( The Cochrane Library Issue 1, 2002), MEDLINE, and EMBASE from 1990 to 2001. Handsearching included relevant journals and bibliographies of all relevant papers and review articles from 1990 up to 2001. In addition, we contacted experts and companies conducting clinical research on ceramic restorations to find other trials or unpublished materials or to clarify ambiguous or missing data.
  
  
  METHODS
  Randomized controlled trials, in which the longevity of ceramic inlays is compared with those of other posterior restorations.
  
  
  METHODS
  Screening of possible studies and data extraction were independently conducted by two reviewers (MH and AY) using a specially designed chart. Authors of studies were contacted for additional information. The methodological quality of studies was assessed in duplicate using individual components. The Cochrane Oral Health Group statistical guidelines were followed and the results expressed as Odds Ratio (OR) and 95% confidence interval for dichotomous outcomes.
  
  
  RESULTS
  Two studies fulfilled the criteria to be included in the review. However, one of them was later excluded from the review, as the study design was not clearly described. The remaining, included study, evaluated the clinical performance of 60 ceramic inlays and 20 gold inlays for five years. Seven of the 60 ceramic inlays and two of the 20 gold inlays failed at five-year review. No ceramic inlays resulted in postoperative pain/discomfort after the treatment, however, one gold inlay did. The power of the included study was not great enough to detect an important difference in longevity and postoperative pain/discomfort between ceramic and gold inlays.
  
  
  CONCLUSIONS
  There is no strong evidence available to support any differences in the clinical performance of ceramic inlays and other posterior restorations. There is a limited number of well-designed clinical trials within this research area. Greater attention to the design and reporting of studies should be given to improve the study quality of ceramic restoration trials.
authors.affiliation: Department of Restorative Dentistry & Endodontology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka Suita, Osaka, Japan, 565-0871. mikarin@dent.osaka-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Hayashi
authors.forename: C A
authors.initials: CA
authors.lastname: Yeung
mesh_terms: D002516:Ceramics / Q000627:therapeutic use*; D006046:Gold / Q000627:therapeutic use; D006801:Humans; D007284:Inlays / Q000379:methods*; D008963:Molar; D016032:Randomized Controlled Trials as Topic; D013997:Time Factors
chemical_list: D006046:Gold