title: Stereochemistry of palladium-mediated synthesis of PAMP-BH3: retention of configuration at P in formation of Pd-P and P-C bonds.
abstract: Treatment of Pd((S,S)-Chiraphos)(o-An)(I) (3, o-An = o-MeOC6H4) with either enantiomer of highly enantioenriched PH(Me)(Ph)(BH3) (1) gave the phosphido-borane complex Pd((S,S)-Chiraphos)(o-An)(P(Me)(Ph)(BH3)) (4) with retention of configuration at phosphorus, as shown by X-ray crystal structure determinations for both diastereomers of 4. Heating either diastereomer of 4 with diphenylacetylene gave Pd((S,S)-Chiraphos)(PhCCPh) (5) and P(o-An)(Me)(Ph)(BH3) (2) with retention of configuration at phosphorus.
authors.affiliation: 6128 Burke Laboratory, Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA.
authors.forename: Jillian R
authors.initials: JR
authors.lastname: Moncarz
authors.forename: Tim J
authors.initials: TJ
authors.lastname: Brunker
authors.forename: David S
authors.initials: DS
authors.lastname: Glueck
authors.forename: Roger D
authors.initials: RD
authors.lastname: Sommer
authors.forename: Arnold L
authors.initials: AL
authors.lastname: Rheingold