title: [Analysis of corneal pathologic changes and laboratory parameters in herpes simplex karatitis patients with ganhuo-shangyanzheng or ganshengyinxuzheng].
abstract: In order to investigate the relationship between Ganhuo shangyanzheng and Can-shengyin xuzheng in herpes simplex karatitis patients, we observed corneal pathologic changes and examined blood levels of prostaglandin F2 (PGF2), prostaglandin E2 (PGF2), tumor necrosis factor (TNF), arginine vasopressin (AVP), norepinephrine (NR), epinephrine (E) in sixty herpes simplex karatitis patients with Ganhou shangyanzheng or Gan-shengyinxuzheng. The results showed that the corneal pathologic changes were corneal ulcer infiltrating to stroma of cornea in Ganhuo shangyanzheng patients, and refractary corneal ulcer with large amount of corneal neovascularizaton and infiltration of corneal stroma in Gan-shengyinxuzheng patients, the blood levels of PGF2, PGE2, TNF, AVP, NE, E in Ganhuo shangyanzheng patients were higher than those in Gan-shengyinxuzheng patients or healthy persons. The results suggest that these parameters may be objective parameters for differential diagnosis of traditional Chinese medicine Zheng types in patients with herpes simplex karatitis.
authors.affiliation: Institute of Combined Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008.
authors.forename: H N
authors.initials: HN
authors.lastname: Zhang
authors.forename: X Q
authors.initials: XQ
authors.lastname: Li
authors.forename: Q H
authors.initials: QH
authors.lastname: Liang
mesh_terms: D003315:Cornea / Q000473:pathology*; D003320:Corneal Ulcer / Q000473:pathology; D003937:Diagnosis, Differential; D015237:Dinoprost / Q000097:blood; D006801:Humans; D016849:Keratitis, Herpetic / Q000097:blood / Q000473:pathology*; D008516:Medicine, Chinese Traditional; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
chemical_list: D014409:Tumor Necrosis Factor-alpha; D015237:Dinoprost