[Clinical significance of plasma PGE2 levels in pre- and post-operative patients with laryngeal carcinoma].
OBJECTIVE
To study the clinical significance of PGE2 Levels in patients with laryngeal carcinoma.


METHODS
Radioimmunoassay was used to evaluate plasma PGE2 levels in 35 patients with laryngeal carcinoma.


RESULTS
The plasma PGE2 levels in patients with laryngeal carcinoma were significant higher than that of normal subjects (P < 0.05), but there was no correlation with the stage of laryngeal carcinoma (P > 0.05). The plasma PGE2 levels of postoperative patients with laryngeal carcinoma were significant lower than that of preoperative patients (P < 0.05). After operation, the plasma PGE2 levels of recurrent patients were significant higher than that in patients with no recurrence (P < 0.01).


CONCLUSIONS
The determination of PGE2 levels in patient plasma may help the diagnosis and prognostic judgment of laryngeal carcinoma.
Li
S Z
SZ
Department of Otolaryngology, 153 Central Hospital of PLA, Zhengzhou 450042.
Liu
H
H
Xu
X L
XL
D002294:Carcinoma, Squamous Cell / Q000097:blood* / Q000601:surgery; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000097:blood* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000097:blood; D011379:Prognosis; D011458:Prostaglandins E / Q000097:blood*
D011458:Prostaglandins E