title: Determination of benzene in urine by static headspace gas chromatography.
abstract: This paper describes the application of static headspace gas chromatography in determining benzene in urine. The method was analytically validated for sensitivity (DL = 42 ng/l), repeatability (RSD = 3% and 4%), and accuracy (71%), and was applied in measuring urine benzene in nonsmokers (N = 14) and smokers (N = 18). All urine samples had measurable benzene concentrations. The method proved sensitive enough to establish a significant statistical difference (P < 0.000614) in urine benzene concentrations between smokers (mean = 760; range = 181-1869 ng/l) and nonsmokers (mean = 214; range = 61-515 ng/l).
authors.affiliation: Institute for Medical Research and Occupational Health, Zagreb, Croatia. Ljiljana.Skender@imi.hr
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Skender
authors.forename: Irena
authors.initials: I
authors.lastname: Brcić
authors.forename: Silva
authors.initials: S
authors.lastname: Zuzul
mesh_terms: D000328:Adult; D001554:Benzene / Q000032:analysis*; D002849:Chromatography, Gas / Q000379:methods; D004785:Environmental Pollutants / Q000652:urine*; D006801:Humans; D012680:Sensitivity and Specificity; D012907:Smoking / Q000652:urine; D016482:Urinalysis / Q000379:methods
chemical_list: D004785:Environmental Pollutants; D001554:Benzene