title: [Development of "Saules" tincture technology].
abstract: The article deals with the production of the "Saules" tincture in a way of selecting an extractive agent concentration, the size of particles of the raw material and the method of extraction. The experiment indicates that the optimum concentration of ethanol in the tincture is 70% V/V, the particles' size is in the range from 1 to 2 mm; the production method recommended for use is percolation. The quality of the tincture was evaluated by determining the quantity of flavonoids and dry residue, the concentration of the ethanol, the density and the microbial contamination. The presence of quercetin, rutin and hyperoside was confirmed using high-pressure liquid chromatography. The stability of the tincture was evaluated.
authors.affiliation: Kauno medicinos universiteto Vaistu technologijos ir farmacijos organizavimo katedra, Mickeviciaus 9, 3000 Kaunas. aiva@kmu.lt
authors.forename: Saule
authors.initials: S
authors.lastname: Velziene
authors.forename: Arūnas
authors.initials: A
authors.lastname: Savickas
authors.forename: Liudas
authors.initials: L
authors.lastname: Svambaris
authors.forename: Vitalis
authors.initials: V
authors.lastname: Briedis
authors.forename: Domininkas
authors.initials: D
authors.lastname: Bernatonis
mesh_terms: D000368:Aged; D002851:Chromatography, High Pressure Liquid; D000431:Ethanol / Q000032:analysis; D005419:Flavonoids / Q000032:analysis; D005767:Gastrointestinal Diseases / Q000628:therapy; D006801:Humans; D010087:Oxides / Q000032:analysis; D008517:Phytotherapy; D028321:Plant Preparations / Q000737:chemistry; D011794:Quercetin / Q000032:analysis; D012431:Rutin / Q000032:analysis
chemical_list: D005419:Flavonoids; D010087:Oxides; D028321:Plant Preparations; D000431:Ethanol; D012431:Rutin; D011794:Quercetin