[Effect of para-aminobenzoic acid on the adhesion of Streptococcus mutans].
OBJECTIVE
To investigate the effects of Para-aminobenzoic acid (PABA) on the adhesion of Streptococcus mutans to saliva-coated hydroxyapatite (S-HA).


METHODS
The adhesion model in vitro established by Gibbons was adopted in this study to quantify adsorptive cells through [3H] thymidine labelling.


RESULTS
PABA solution over a range of concentration from 10(-9) to 10(-3) g/L could inhibit the attachment of S. mutans to S-HA effectively, and the inhibition declined when the concentration of PABA solution was 10(-3) g/L.


CONCLUSIONS
PABA can inhibit the adherence of Streptococcus mutans to S-HA effectively.
Guo
B
B
School of Stomatology, WCUMS, Chengdu 610041, China.
Zhou
X
X
Hu
T
T
Li
J
J
Li
L
L
D010129:4-Aminobenzoic Acid / Q000494:pharmacology*; D001422:Bacterial Adhesion / Q000187:drug effects*; D017886:Durapatite; D012463:Saliva; D013295:Streptococcus mutans / Q000502:physiology*
D017886:Durapatite; D010129:4-Aminobenzoic Acid