Primary myeloid sarcoma of the gynecologic tract: a report of two cases progressing to acute myeloid leukemia.
Primary gynecologic myeloid sarcomas are rare, and their diagnosis is often difficult. Differential diagnosis includes lymphomas and carcinomas of the gynecologic tract. We report the clinical, morphological, immunohistochemical and cytogenetic features of two cases of chloromas of the female genital tract, which progressed to acute myeloid leukemia in spite of aggressive therapy.
Hernández
José-Angel
JA
Department of Hematology, Hospital de Mataró, Carretera de Cirera s/n. 08304 Mataró, Barcelona, Spain. jahernandez@csm.scs.es
Navarro
José-Tomás
JT
Rozman
María
M
Ribera
Josep-María
JM
Rovira
Montserrat
M
Bosch
María-Alba
MA
Fantova
María-José
MJ
Mate
José-Luis
JL
Millá
Fuensanta
F
D000208:Acute Disease; D001943:Breast Neoplasms / Q000556:secondary; D003937:Diagnosis, Differential; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D005833:Genital Neoplasms, Female / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000209:etiology; D007951:Leukemia, Myeloid / Q000209:etiology*; D015470:Leukemia, Myeloid, Acute / Q000209:etiology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D016609:Neoplasms, Second Primary / Q000209:etiology; D023981:Sarcoma, Myeloid / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*