title: Olanzapine efficacy in the treatment of essential tremor.
abstract: We investigated the anti-tremor effect of olanzapine, a novel atypical antidopaminergic drug, in 37 patients with essential tremor (ET) in an open-label and prospective study by clinical scoring and patient self-evaluation. Olanzapine monotherapy appears to be efficacious for the treatment of ET. Further clinical trials with control groups are indicated to establish the efficacy of olanzapine in patients with ET.
authors.affiliation: Department of Neurology, Atatürk Education and Research Hospital Izmir, Izmir, Turkey. yetimalar@hotmail.com
authors.forename: Y
authors.initials: Y
authors.lastname: Yetimalar
authors.forename: G
authors.initials: G
authors.lastname: Irtman
authors.forename: N
authors.initials: N
authors.lastname: Gürgör
authors.forename: M
authors.initials: M
authors.lastname: Başoğlu
mesh_terms: D000368:Aged; D001569:Benzodiazepines; D016009:Chi-Square Distribution; D020329:Essential Tremor / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D010890:Pirenzepine / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D011446:Prospective Studies
chemical_list: D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine