title: [Measurement of forces between biomolecules by atomic force microscopy].
abstract: The intermolecular forces of the biological samples may be measured by atomic force microscopy, which has provided a powerful means for us to understand the principles of living phenomena. Some systems in which the interaction forces between biomolecules have been measured hitherto include: 1. ligand-receptor; 2. actin-myosin; 3. proteoglycans; 4. DNA complementary strands and nucleotides; 5. special organic chemical groups. A literature review on these objects is presented in this article.
authors.affiliation: Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850.
authors.forename: Y G
authors.initials: YG
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Wang
mesh_terms: D046911:Macromolecular Substances; D018625:Microscopy, Atomic Force / Q000379:methods*; D009696:Nucleic Acids / Q000737:chemistry; D011506:Proteins / Q000737:chemistry
chemical_list: D046911:Macromolecular Substances; D009696:Nucleic Acids; D011506:Proteins