title: Multiple sclerosis and parkinsonism: a case report.
abstract: Multiple sclerosis (MS) is a well-known disease characterized by the distribution of plaques in the periventricular and subcortical white matter. Although plaques can also be found in the striatum, pallidum and thalamus, extrapyramidal symptoms are very rare in MS. However, the association of MS and parkinsonism is still a controversial topic as it has not been established whether these two conditions occur coincidentally or causally. In the literature, eleven cases of parkinsonism associated with MS have been described. Here, we report a patient with clinically definite MS and signs of parkinsonism. Our patient had slow progressive bradykinesia, static tremor and bradymimia that were not associated with exacerbation or progression of the MS. This rare and interesting association of multiple sclerosis with parkinsonism is discussed in the light of literature reports.
authors.affiliation: Department of Neurology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey. ozturkv@hotmail.com
authors.forename: Vesile
authors.initials: V
authors.lastname: Ozturk
authors.forename: Egemen
authors.initials: E
authors.lastname: Idiman
authors.forename: Ihsan S
authors.initials: IS
authors.lastname: Sengun
authors.forename: Zafer
authors.initials: Z
authors.lastname: Yuksel
mesh_terms: D001921:Brain / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000175:diagnosis; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000150:complications* / Q000175:diagnosis