[Prognostic significance of CD57+ cell level and pTNM staying system in patients with laryngeal cancer].
OBJECTIVE
To analyze the prognostic value of the pTNM clinical staying system, as well as the CD57+ cells level in peripheral blood samples of the patients with laryngeal carcinoma.


METHODS
The CD57+ cells level of peripheral blood was determined with SAP method in 34 patients with laryngeal carcinoma and 16 normal subjects. The pTNM clinical stage was T1-2 in 13, T3-4 in 21; pN+ in 10, pN0 in 24; supraglottis in 8, glottis in 23; hypoglottis in 3; pathologic differentiation G1 in 11, G2,3 in 23.


RESULTS
The CD57+ cells level significantly increased (pN+ vs. pNo). In the 12nd month actual survival were significantly different (T1,2 vs. T3,4, pN0 vs. pN+, G1 vs G2,3, supraglottis vs. glottis and hypoglottis, CD57+ > or = 15% vs. CD57+ < 15%). In the 24th month and 36th month actual survival were significantly different (pN0 vs. pN+, G1 vs G2,3, supraglottis. glottis and hypoglottis, CD57+ > or = 15% vs. CD57+ < 15%). In the 48th month actual survival were significantly different only (pN0 vs. pN+, supraglottis vs. glottis and hypo glottis, CD57+ > or = 15% vs. CD57+ < 15%).


CONCLUSIONS
These results suggested that the assessment of pTNM system and the CD57+ cells level have significance for prognosis of patients with laryngeal carcinoma.
Zheng
M
M
Department of Otolaryngology, First People's Hospital of Jining, Jining 272111.
Luan
X
X
D000368:Aged; D018959:CD57 Antigens / Q000097:blood*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D015996:Survival Rate
D018959:CD57 Antigens