title: Extradural spinal, bone marrow, and renal nephroblastoma.
abstract: A 1-year-old, female intact Shetland sheepdog presented with acute onset of neurological signs. Physical examination revealed a large abdominal mass. Neurological examination revealed multifocal disease with neck pain, short-strided forelimbs, and hind-limb paresis with loss of tail and anal tone. Blood work, imaging techniques, cytopathology, and histopathology led to a diagnosis of renal, bone-marrow, and extradural spinal nephroblastoma. This report documents potential clinical and pathological manifestations of canine nephroblastoma that have not been previously reported.
authors.affiliation: Department of Clinical Studies, Veterinary Hospital of the University of Pennsylvania, 3900 Delancey Street, Philadelphia, Pennsylvania 19104, USA.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Gasser
authors.forename: William W
authors.initials: WW
authors.lastname: Bush
authors.forename: Sionagh
authors.initials: S
authors.lastname: Smith
authors.forename: Raquel
authors.initials: R
authors.lastname: Walton
mesh_terms: D000818:Animals; D019046:Bone Marrow Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D004285:Dogs; D005260:Female; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008159:Lumbar Vertebrae; D020335:Paraparesis / Q000209:etiology / Q000662:veterinary; D011859:Radiography; D013125:Spinal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D009396:Wilms Tumor / Q000150:complications / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*