title: Leveraging process integration in early drug discovery.
abstract: Recent advances in new analysis and prediction concepts in informatics, statistics and computational chemistry have drawn attention to mining the enormous flood of information generated from ultra-high-throughput screening (uHTS) and early drug discovery more effectively. This review analyses current infrastructure and process concepts in data analysis, storage and mining, with a particular focus on high-throughput technologies. It also provides examples of how these techniques have been applied successfully together with underlying reasons for these developments.
authors.affiliation: Evotec OAI, Schnackenburgallee 114, D-22525 Hamburg, Germany. nicolas.fay@evotecoai.com
authors.forename: Nicolas
authors.initials: N
authors.lastname: Fay
authors.forename: Dirk
authors.initials: D
authors.lastname: Ullmann
mesh_terms: D019295:Computational Biology / Q000639:trends*; D030541:Databases, Genetic; D004353:Drug Evaluation, Preclinical / Q000639:trends; D010600:Pharmacology / Q000639:trends*