Applications of positron-emitting halogens in PET oncology (Review).
The positron-emitting radiohalogens 18F, 75Br, 76Br, and 124I are reviewed regarding their relevance for positron emission tomography (PET) in oncology. Relevant production routes of these cyclotron-generated isotopes are given, followed by publications that deal with applications of these radiohalogens. This article tries to cover the whole literature for the non-conventional isotopes 75Br, 76Br, and 124I. From the literature on 18F, only articles since 2000 are considered. Here, the emphasis is also given to alternative biomarkers beyond [18]2-fluoro-2-deoxyglucose ([18F]FDG).
Glaser
Matthias
M
Imaging Research Solutions Ltd., Hammersmith Hospital, London W12 0NN, UK. m.glaser@csc.mrc.ac.uk
Luthra
Sajinder K
SK
Brady
Frank
F
D000818:Animals; D001967:Bromine Radioisotopes; D002986:Clinical Trials as Topic; D004583:Electrons; D005462:Fluorine Radioisotopes; D006801:Humans; D007457:Iodine Radioisotopes; D007553:Isotope Labeling; D051379:Mice; D015394:Molecular Structure; D009369:Neoplasms / Q000000981:diagnostic imaging*; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging; D016719:Radioimmunodetection; D019275:Radiopharmaceuticals / Q000737:chemistry / Q000493:pharmacokinetics; D012680:Sensitivity and Specificity; D014055:Tomography, Emission-Computed
D001967:Bromine Radioisotopes; D005462:Fluorine Radioisotopes; D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals