[Specific complications after lung transplantation for cystic fibrosis].
Complications observed after lung transplantation are well described for the different indications. Certain complications are specifically observed in patients with cystic fibrosis who have reached the stage of major respiratory failure. The most specific complications result from digestive tract manifestations of the disease: malabsorption of lipophilic drugs, osteoporosis, diabetes. These patients also have a risk of infection: carriage of resistant strains, sinus colonization, poor immunization against certain viruses. They are particularly susceptible to post-transplantation lymphoproliferative disorder and neurological drug toxicity. Finally, in certain emergency situations, grafts from living donors may create specific problems. Despite these complications, lung transplantation remains the most effective treatment for respiratory failure due to cystic fibrosis.
Allard-Recoque
C
C
Service de Pneumologie, Hôpital Louis-Pradel, BP Lyon-Montchat, 69394 Lyon Cedex 03.
Bertocchi
M
M
Mornex
J-F
JF
D000359:Aftercare / Q000379:methods; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications / Q000601:surgery*; D003586:Cytomegalovirus Infections / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D006084:Graft Rejection / Q000209:etiology; D006801:Humans; D016867:Immunocompromised Host; D007239:Infections / Q000209:etiology; D019520:Living Donors; D016040:Lung Transplantation / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000209:etiology; D010024:Osteoporosis / Q000209:etiology; D018579:Patient Selection; D011182:Postoperative Care / Q000379:methods; D012131:Respiratory Insufficiency / Q000209:etiology; D012307:Risk Factors; D012720:Severity of Illness Index; D012852:Sinusitis / Q000209:etiology; D016896:Treatment Outcome