[Determination of elemenyl piperidine salt in water by capillary gas chromatography].
beta-Elemene and its derivatives were hopeful new antitumor drugs. A method for determination of elemenyl piperidine salt in water has been developed with capillary gas chromatography. The samples were neutralized by sodium carbonate and extracted by n-heptane. n-Octadecane was used as the internal standard. The linear range was from 10 g/L to 100 g/L, with a correlation coefficient of 0.9998. The average recovery of the method was 99.96% and the RSD was 0.46% (n = 5). The coefficient of variation was less than 2%. The method is simple, rapid, accurate and can be applied to the determination of the nitrogen-containing compounds of beta-elemene.
Gong
G L
GL
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Cheng
G B
GB
Hu
J H
JH
Dai
J Y
JY
D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis; D002849:Chromatography, Gas / Q000379:methods; D010880:Piperidines / Q000032:analysis*; D010936:Plant Extracts / Q000032:analysis*; D012717:Sesquiterpenes; D014867:Water / Q000737:chemistry
D000972:Antineoplastic Agents, Phytogenic; D010880:Piperidines; D010936:Plant Extracts; D012717:Sesquiterpenes; C445979:beta-elemene; D014867:Water; C032727:piperidine