title: Outcomes of sentinel node biopsy for breast cancer in British Columbia, 1996 to 2001.
abstract: BACKGROUND
  This study evaluated the outcomes of the first 5 years of sentinel node biopsy (SNB) in British Columbia (BC), Canada, 1996 to 2001.
  
  
  METHODS
  There were 547 SNB procedures for breast cancer performed by 29 surgeons at 12 hospitals in BC between October 1996 and July 2001. Identification, accuracy, and false-negative rates were determined and correlated to patient, tumor, and surgical factors with the chi-square test.
  
  
  RESULTS
  SNB mapping was performed using blue dye alone (15%), radiopharmaceutical alone (6%), or both (79%). A completion axillary dissection was performed in 93%. A median of 2 (range 1 to 16) sentinel nodes was biopsied. The overall identification rate was 88%, accuracy was 92%, and false-negative rate was 22%. All rates were improved in younger (age <50 years) compared with older women. A positive lymphoscintiscan and the mapping agent used were associated with higher identification rates but not accuracy or false negative rates. Increasing surgeon experience was not significantly associated with improvements in identification or false-negative rates.
  
  
  CONCLUSIONS
  The potential of SNB was not fully translated into surgical practice in BC by 2001.
authors.affiliation: Radiation Therapy Program, BC Cancer Agency, Vancouver Island Centre, 2410 Lee Avenue, Victoria, BC, V8R 6V5, Canada.
authors.forename: Boon
authors.initials: B
authors.lastname: Chua
authors.forename: Ivo A
authors.initials: IA
authors.lastname: Olivotto
authors.forename: James C
authors.initials: JC
authors.lastname: Donald
authors.forename: Allen H
authors.initials: AH
authors.lastname: Hayashi
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Doris
authors.forename: Laurence J
authors.initials: LJ
authors.lastname: Turner
authors.forename: Gary D
authors.initials: GD
authors.lastname: Cuddington
authors.forename: Noelle L
authors.initials: NL
authors.lastname: Davis
authors.forename: Conrad H
authors.initials: CH
authors.lastname: Rusnak
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D001955:British Columbia / Q000453:epidemiology; D002170:Canada / Q000453:epidemiology; D003625:Data Collection; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008875:Middle Aged; D010865:Pilot Projects; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000706:statistics & numerical data; D016896:Treatment Outcome