title: Comparison of neonatal outcome including cerebral palsy between abruptio placentae and placenta previa.
abstract: OBJECTIVE
  Our purpose was to evaluate the neonatal prognosis after abruptio placentae and placenta previa during pre-term gestation.
  
  
  METHODS
  A case-control study was performed using a logistic regression model. A poor outcome was defined as neonatal death occurring before hospital discharge or a diagnosis of cerebral palsy.
  
  
  RESULTS
  A poor outcome was more frequent in cases of abruptio placentae (11/42, 26.2%) than in placenta previa (2/72, 2.8%) and pre-term labor (1/120, 0.8%). The difference was mainly due to the incidence of cerebral palsy. A significant association of abruptio placentae (odds ratio (OR) 61.0, 95% confidence interval (CI 3.4-1084), delivery at <31 weeks of gestation (OR 19.0, CI 2.8-128.8), and low Apgar score (<7) at 5min (OR 70.8, CI 16.5-304.9) with increased risk of poor outcome was found in the logistic regression model that controlled for confounding effects. In abruptio placentae, a low Apgar score (<7) at 5min (OR 19.8, CI 2.0-197.8) was associated with increased risk of poor outcome in the logistic regression model.
  
  
  CONCLUSIONS
  From the standpoint of poor perinatal outcome including cerebral palsy, abruptio placentae was the most significant clinical entity in pre-term gestation.
authors.affiliation: Department of Obstetrics and Gynecology, Kagoshima City Hospital, Kagoshima, Japan. ymatsuda@obgy.twmu.ac.jp
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Takatsugu
authors.initials: T
authors.lastname: Maeda
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kouno
mesh_terms: D000037:Abruptio Placentae / Q000150:complications*; D000328:Adult; D016022:Case-Control Studies; D002547:Cerebral Palsy / Q000209:etiology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007234:Infant, Premature; D016015:Logistic Models; D015999:Multivariate Analysis; D010923:Placenta Previa / Q000150:complications*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies