[Effects of processing on antioxidation of Radix et Rhizoma Rhei and Rhizoma Polygoni Cuspidati].
OBJECTIVE
To investigate the effects of Processing on antioxidation of Radix et Rhizoma Rhei and Rhizoma Polygoni Cuspidati.


METHODS
The oxygen free radicals generation system and mouse liver homogenate lipid peroxidation in vitro were used.


RESULTS
The processed products of Radix et Rhizoma Rhei and Rhizoma Polygoni Cuspidati could scavenge superoxide radical (O2-.) generated through hypoxanthine-oxidase system and (.OH) generated through Fenton action, and inhibit lipid peroxidation induced by hydroxyl radical generation system, respectively. There existed significant differences among the different processed products.


CONCLUSIONS
After Radix et Rhizoma Rhei and Rhizoma Polygoni Cuspidati were processed, their effects became weaker.
Kong
L D
LD
Nanjing University, School of Life Sciences, State Key Laboratory of Pharmaceutial Biotechnology, Nanjing 210093, Jiangsu, China.
Yang
C
C
Qiu
X
X
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology*; D006358:Hot Temperature; D017665:Hydroxyl Radical; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D028502:Polygonum / Q000737:chemistry; D012250:Rheum / Q000737:chemistry; D027343:Rhizome / Q000737:chemistry; D013481:Superoxides; D013678:Technology, Pharmaceutical / Q000379:methods
D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D013481:Superoxides; D017665:Hydroxyl Radical