Ramipril treatment in a patient with glycogen storage disease I non-A.
We studied the effect of ramipril on proteinuria and mild hypertension in a 21-year-old patient affected by glycogen storage disease type I non-A. After few months of therapy we obtained a decrease in total urine protein excretion that later re-increased in spite of the high dose of ACE inhibitor. Even if ACE inhibitors are the only effective therapy for GSD I nephropathy, further studies are requested.
Giannì
M L
ML
Department of Pediatrics, University of Milan, San Paolo Hospital, Milan, Italy. marialorella.gianni@tin.it
Bonvissuto
M
M
Gallieni
M
M
Testolin
C
C
Racchi
E
E
Riva
E
E
D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D005952:Glucose-6-Phosphatase / Q000235:genetics; D005953:Glycogen Storage Disease Type I / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics; D006801:Humans; D006977:Hypertension, Renal / Q000188:drug therapy / Q000235:genetics; D007674:Kidney Diseases / Q000188:drug therapy / Q000235:genetics; D008297:Male; D011507:Proteinuria / Q000150:complications; D017257:Ramipril / Q000627:therapeutic use*
D000806:Angiotensin-Converting Enzyme Inhibitors; D005952:Glucose-6-Phosphatase; D017257:Ramipril