title: [Development and analysis of revitalizing tincture].
abstract: The article deals with the production of the complex tincture of Hyperici herba 80.0 g, Cinnamomi cortex 20.0 g, Rosmarini folium 20.0 g, Lavandulae flos 20.0 g, Zingiberis rhizoma 60.0 g and the selection of an extracting liquid phase, and the choice of extraction method. The experimentally determined optimal conditions for tincture preparation were as follows: concentration of ethanol--70% (V/V), the particle size of the leaves, herb, flowers--2.0-3.0 mm, for the bark and the roots--0.3-0.5 mm, the extraction method--percolation. The quality of the tincture was evaluated by analyzing the sum of flavonoids (recalculated into equivalent amount of rutin), dry residue, the concentration of ethanol, density of the extractive preparation, and microbial contamination. Also the overall appearance was checked, the identification of flavonoids was performed by color reactions and high-pressure liquid chromatography.
authors.affiliation: Kauno medicinos universiteto Vaistu technologijos ir farmacijos organizavimo katedra, A. Mickeviciaus 9, 3000 Kaunas. vtfo@kmu.lt
authors.forename: Zenona
authors.initials: Z
authors.lastname: Kalveniene
authors.forename: Arūnas
authors.initials: A
authors.lastname: Savickas
authors.forename: Liudvinas
authors.initials: L
authors.lastname: Svambaris
authors.forename: Vitalis
authors.initials: V
authors.lastname: Briedis
authors.forename: Domininkas
authors.initials: D
authors.lastname: Bernatonis
mesh_terms: D002851:Chromatography, High Pressure Liquid; D002935:Cinnamomum zeylanicum; D000431:Ethanol / Q000032:analysis; D020939:Zingiber officinale; D006801:Humans; D020902:Hypericum; D027523:Lavandula; D028321:Plant Preparations / Q000032:analysis; D027542:Rosmarinus
chemical_list: D028321:Plant Preparations; D000431:Ethanol