title: Guided tissue regeneration-based root coverage utilizing collagen membranes: technique and case reports.
abstract: Gingival recession defects have traditionally been treated with various grafting procedures. Recently, guided tissue regeneration with collagen membranes has shown promising results. This article reviews the rationale, indications, contraindications, and clinical methods for the use of bioabsorbable collagen membrane barriers. Several properties make collagen membranes attractive candidates for use as barriers in guided tissue regeneration-based root coverage procedures. These include the inhibition of epithelial migration and promotion of new connective tissue attachment; the ability to aggregate platelets, thereby facilitating wound stabilization and maturation; the promotion of cellular migration and wound closure; the elimination of the need for reentry surgery; and the ability to augment tissue thickness. Cases are presented to illustrate the surgical principles and techniques.
authors.affiliation: Department of Periodontics/Prevention/Geriatrics, University of Michigan, School of Dentistry, Ann Arbor, Michigan 48109-1078, USA. homlay@umich.edu
authors.forename: Hom-Lay
authors.initials: HL
authors.lastname: Wang
authors.forename: Khalaf F
authors.initials: KF
authors.lastname: Al-Shammari
mesh_terms: D020341:Absorbable Implants; D001672:Biocompatible Materials / Q000627:therapeutic use; D002448:Cell Adhesion; D002465:Cell Movement; D002630:Chemotactic Factors / Q000627:therapeutic use; D003094:Collagen / Q000627:therapeutic use; D003238:Connective Tissue / Q000473:pathology; D000075202:Contraindications; D004848:Epithelium / Q000473:pathology; D005889:Gingival Recession / Q000601:surgery*; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation* / Q000379:methods; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D008567:Membranes, Artificial; D010974:Platelet Aggregation; D012907:Smoking / Q000009:adverse effects; D014092:Tooth Root / Q000601:surgery*; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D002630:Chemotactic Factors; D006490:Hemostatics; D008567:Membranes, Artificial; D003094:Collagen