title: Large geodes in rheumatoid arthritis without joint destruction.
abstract: Although subchondral geodes are a well-known radiological feature of rheumatoid arthritis (RA), large geodes are uncommon. Progressive bone damage with pathological fractures has been reported. We report the case of a 49-year-old man with seropositive RA in whom large, rapidly progressive geodes in the wrists, hands, and feet contrasted with the absence of joint destruction, good functional tolerance, and moderate abnormalities of markers for inflammation. The location and rapid progression of the cyst-like lesions in this patient were highly unusual.
authors.affiliation: Rheumatology department, Hôpital d'Instruction des Armées Desgenettes, boulevard Pinel, 69275 Lyon cedex 03, France.
authors.forename: Didier
authors.initials: D
authors.lastname: Rabar
authors.forename: Philippe
authors.initials: P
authors.lastname: Crozes
authors.forename: Murielle
authors.initials: M
authors.lastname: Lernoud
authors.forename: Francis
authors.initials: F
authors.lastname: Meignan
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D001845:Bone Cysts / Q000000981:diagnostic imaging* / Q000209:etiology*; D002348:Carpal Bones / Q000000981:diagnostic imaging; D018450:Disease Progression; D005529:Foot Bones / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013639:Tarsal Bones / Q000000981:diagnostic imaging
chemical_list: D018501:Antirheumatic Agents