[Natural history of cervical arterial dissections. Review of the literature and preliminary results from a national study group].
Few studies have been devoted to the natural history of cervical artery dissection (CAD). This review shows that apart from neurological damage due to initial stroke, the prognosis of DAC is good. Indeed, the risk of recurrent DAC or recurrent stroke is very low, under 1% per year in patients without typical connective tissue disease. Patients with connective tissue disease (Ehlers Danlos syndrome or Marfan syndrome) or familial history of arterial dissection have an increased risk of recurrent CAD. However, the number of cases due to these diseases remains very low. The other risk factors for recurrent CAD or stroke remain unknown. The benefit of antithrombotic treatments at the acute phase of CAD or for secondary prevention has been never assessed in a randomized clinical trial.
Touzé
E
E
Service de Neurologie, Centre hospitalier Sainte-Anne, 1, rue Cabanis, 75674 Paris cedex 14. touze@chsa.broca.inserm.fr
Gauvrit
J Y
JY
D000208:Acute Disease; D000328:Adult; D000784:Aortic Dissection / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D001158:Arteries; D018450:Disease Progression; D004535:Ehlers-Danlos Syndrome / Q000150:complications; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005602:France / Q000453:epidemiology; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000150:complications; D008875:Middle Aged; D009333:Neck / Q000098:blood supply*; D011379:Prognosis; D012008:Recurrence; D012307:Risk Factors; D020521:Stroke / Q000209:etiology*; D016896:Treatment Outcome
D005343:Fibrinolytic Agents