[Study on relationship between the reflux laryngitis and gastroesophageal reflux disease].
OBJECTIVE
To investigate the relationship between reflux laryngitis and gastroesophageal reflux disease (GRED).


METHODS
130 Patients of refractory chronic laryngitis with upper endoscopy and ambulatory 24-hr esophageal pH-metry. The patients of gastroesophageal reflux disease were divided into two groups. Group A was treated with antacids and motile medications. Group B was control.


RESULTS
45 (34.6%) gastroesophageal reflux disease were found in 130 cases. 21 cases(91.3%) were healed in group A. 3 of 22 cases (13.6%) were healed in control (P < 0.01).


CONCLUSIONS
The gastroesophageal reflux disease was an important cause of the reflux laryngitis which symptoms and signs can be healed by antacids and motile medications.
Gong
Q
Q
Department of Otolaryngology, Jiangwan Hospital, Shanghai 200432.
Zhou
K
K
D000328:Adult; D000863:Antacids / Q000627:therapeutic use; D004294:Domperidone / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007827:Laryngitis / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008875:Middle Aged
D000863:Antacids; D004365:Drugs, Chinese Herbal; D004294:Domperidone