[The detection of Epstein-Barr virus in middle ear effusion of secretory otitis media].
OBJECTIVE
To study the involvement of Epstein-Barr Virus (EBV) in the pathogenesis of secretory otitis media (SOM).


METHODS
Epstein-Barr Virus (EBV) in blood serum, oral gargle and middle ear effusion was detected by polymerase chain reaction (PCR) method in 34 patients with secretory otitis media and 20 normal subjects.


RESULTS
The detection rate of EBV in serum and oral gargle in the SOM group was remarkably higher than that in normal control group (P < 0.01). EBV positive rate of middle ear effusion was higher than that of serum group in SOM individuals.


CONCLUSIONS
EBV plays a role in the pathogenesis of secretory otitis media (SOM).
Dai
X Q
XQ
Department of Patholgoy, the Twelfth Hospital of Army, XinJiang, Shule 844200.
Wang
G F
GF
Wang
Z
Z
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010034:Otitis Media with Effusion / Q000821:virology*; D016133:Polymerase Chain Reaction