title: [Measurement of distortion product otoacoustic emissions in guinea pig].
abstract: OBJECTIVE
  To establish a stable detecting method of distortion product otoacoustic emissions (DPOAEs).
  
  
  METHODS
  After cutting off tragus, seven healthy pigmented guinea pigs (thirteen ears) were selected to measure the DPOAEs at the frequency of 2f1-f2 (cubic DPOAEs). The I/O function and latency at f2 = 2, 4, 6 kHz were analyzed.
  
  
  RESULTS
  The incidence of DPOAEs at all frequencies was 100%. The maximal amplitude of input-output function was (27.24 +/- 4.15) dB SPL, (27.98 +/- 4.05) dB SPL and (41.45 +/- 1.20) dB SPL respectively; latency was (2.06 +/- 0.21) ms, (1.52 +/- 0.16) ms and (1.37 +/- 0.08) ms at the corresponding frequencies.
  
  
  CONCLUSIONS
  After the improvement of detection, it is satisfactory to measuring DPOAE in animals because of the high incidence, high amplitude and good repetition.
authors.affiliation: Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022.
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: W
authors.initials: W
authors.lastname: Kong
authors.forename: W
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000818:Animals; D003051:Cochlea / Q000502:physiology; D006168:Guinea Pigs; D017084:Otoacoustic Emissions, Spontaneous