Senile systemic amyloidosis presenting as bilateral carpal tunnel syndrome.
A 74-year-old woman who had developed numbness in both hands was diagnosed as having bilateral carpal and right cubital tunnel syndrome and underwent bilateral carpal and right cubital tunnel release. Transthyretin immunoreactive amyloid deposits were seen on specimens and were also detected in gastric, duodenal and ileal mucosal biopsies. The transthyretin gene analysis showed no mutation. This is a rare case of senile systemic amyloidosis presenting as carpal tunnel syndrome.
Takei
Yo-ichi
Y
Third Department of Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan. y-takei@hsp.md.shinshu-u.ac.jp
Hattori
Takeshi
T
Gono
Takahisa
T
Tokuda
Takahiko
T
Saitoh
Satoru
S
Hoshii
Yoshinobu
Y
Ikeda
Shu-ichi
S
D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis* / Q000235:genetics; D002349:Carpal Tunnel Syndrome / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D011228:Prealbumin / Q000235:genetics
D011228:Prealbumin