[Detection of bate 2-microglobulin fibronection and interleukin 2 content in patients with nasopharyngeal carcinoma].
OBJECTIVE
To study the clinical significance of detecting of beta 2-microglobulin (beta 2-MG). Fibronection (Fn) and interleukin 2 (IL-2) in patients with nasopharyngeal carcinoma.


METHODS
The levels of serum beta 2-MG and IL-2 in 32 patients with nasopharyngeal carcinoma were determined by radioimmunoassay, radial immunodiffusion and ELISA before and after radiotherapy.


RESULTS
The levels of serum beta 2-MG in patients with nasopharyngeal carcinoma were significantly higher than that in controls (P < 0.05); but serum Fn and IL-2 in patients were significantly lower than that in controls (P < 0.05). The level of serum beta 2-MG decreased in patients after radiotherapy, but the serum Fn and IL-2 increased in patients after radiotherapy.


CONCLUSIONS
Detection of serum beta 2-MG, Fn and IL-2 was useful in clinical diagnosis and prognosis observation of nasopharyngeal carcinoma.
Lin
Q
Q
Department of Otolaryngology, China PLA 476 Hospital, Fuzhou 350002.
Fu
F
F
Zhang
G
G
D000328:Adult; D000368:Aged; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D007376:Interleukin-2 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000097:blood*; D011379:Prognosis; D001613:beta 2-Microglobulin / Q000097:blood*
D005353:Fibronectins; D007376:Interleukin-2; D001613:beta 2-Microglobulin