title: Alternative approach to massive gastrointestinal bleeding in ulcerative colitis: highly selective transcatheter embolization.
abstract: Massive haemorrhage in ulcerative colitis mainly occurs as a result of exacerbated disease, usually acute or even fulminant colitis. Emergency proctocolectomy is currently advocated as the only reliable treatment of this patient group. However, this type of surgical intervention has a high rate of morbidity and mortality. Recently, several promising studies have been published that describe transcatheter embolization for the treatment of massive lower gastrointestinal bleeding in cases of bleeding colonic diverticular disease and angiodysplasia. Success rates of 48-88% have been reported. To avoid the high risk associated with emergency colectomy, this modern procedure was performed in an ulcerative colitis patient with intractable lower gastrointestinal bleeding. To our knowledge, this is the first patient with ulcerative colitis presenting with massive lower gastrointestinal blood loss to be successfully treated by highly selective transcatheter embolization. This interventional procedure is suggested as an alternative therapeutic approach to haematochezia in selected ulcerative colitis patients.
authors.affiliation: Department of Gastroenterology, VU Medical Centre, Postbus 7057, 1007 MB Amsterdam, the Netherlands. R.Mallant-Hent@vumc.nl
authors.forename: Rosalie Ch
authors.initials: RCh
authors.lastname: Mallant-Hent
authors.forename: Ad A
authors.initials: AA
authors.lastname: van Bodegraven
authors.forename: Stephan G M
authors.initials: SG
authors.lastname: Meuwissen
authors.forename: Radu A
authors.initials: RA
authors.lastname: Manoliu
mesh_terms: D003093:Colitis, Ulcerative / Q000150:complications* / Q000000981:diagnostic imaging; D003106:Colon / Q000098:blood supply / Q000000981:diagnostic imaging; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D011859:Radiography