title: Osseous malignant non-Hodgkin's B-cell lymphoma associated with total hip replacement.
abstract: We report a case of non-Hodgkin B-cell lymphoma within the bony base of an implanted acetabular cup of a total hip arthroplasty. The diagnosis was made while revising a loose prosthesis and treatment of a non-union of a periprosthetic fracture. This case demonstrates that it is important to consider tumour development in differential diagnoses of pain originating in and around a loose prosthesis. It also illustrates the need for better understanding of the relationship between haematopoietic malignancies and possible carcinogenic effects of implant debris.
authors.affiliation: Department of Orthopaedics and Trauma, St. James University Hospital, Leeds, UK. kulsoomasad@hotmail.com
authors.forename: A A
authors.initials: AA
authors.lastname: Syed
authors.forename: M
authors.initials: M
authors.lastname: Agarwal
authors.forename: G
authors.initials: G
authors.lastname: Fenelon
authors.forename: M
authors.initials: M
authors.lastname: Toner
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D005264:Femoral Fractures / Q000000981:diagnostic imaging; D005269:Femur; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000473:pathology*; D009361:Neoplasm Invasiveness; D011859:Radiography