title: The pre-ribosomal network.
abstract: Recent achievements in yeast functional proteomics have significantly advanced our knowledge about ribosome biogenesis. Here, we present a program developed to integrate data from various proteome analyses with cell biological data on components present in the ribosome producing factories. This program allows users to attribute factors to certain complexes and to specific steps of ribosome biogenesis. Thus, it helps to gain novel insights into the complex network involved in maturation of ribosomal subunits. The database can be accessed at the URL http://www.pre-ribosome.de.
authors.affiliation: Laboratoire de Biologie Moleculaire Eucaryote, F-32062 Toulouse, France.
authors.forename: Philipp
authors.initials: P
authors.lastname: Milkereit
authors.forename: Holger
authors.initials: H
authors.lastname: Kühn
authors.forename: Nicole
authors.initials: N
authors.lastname: Gas
authors.forename: Herbert
authors.initials: H
authors.lastname: Tschochner
mesh_terms: D015415:Biomarkers / Q000032:analysis; D046911:Macromolecular Substances; D008958:Models, Molecular; D020543:Proteome / Q000032:analysis; D012269:Ribosomal Proteins / Q000032:analysis* / Q000145:classification; D012270:Ribosomes / Q000737:chemistry / Q000378:metabolism*; D015003:Yeasts / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D046911:Macromolecular Substances; D020543:Proteome; D012269:Ribosomal Proteins