[Human papillomavirus DNA test in nasal polypsis].
OBJECTIVE
To evaluate pathogenesis of nasal polypsis.


METHODS
To detect HPV in 26 pathological samples of 13 cases by polymerase chain reaction(PCR). Ten cases of normal nasal mucous were used as control.


RESULTS
HPV-DNA was positive 12 cases(92.3%) in 13 cases of the first surgical operation by PCR. HPV-DNA was positive 5 cases (38.5%) in 13 cases of the second surgical operation by PCR. The most HPV type was HPV6. HPV-DNA was negative in 10 cases of control.


CONCLUSIONS
The results showed that HPV plays an etiologic role in the development of nasal polypsis.
Zhou
Y
Y
Department of Otolaryngology, Third Clinical College, Peking University, Beijing 100083.
Hu
M
M
Liu
C
C
D000328:Adult; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000821:virology*; D027383:Papillomaviridae / Q000235:genetics*; D016133:Polymerase Chain Reaction
D004279:DNA, Viral