title: [Effects of low energy laser on tooth movement and remodeling of alveolar bone in rabbits].
abstract: OBJECTIVE
  The aim of this study was to investigate effects of low energy laser on the experimental tooth movement and the remodeling of alveolar bone in rabbits.
  
  
  METHODS
  A total of 42 white rabbits were chosen and randomized into one control group and six experimental groups, with 6 rabbits in each group. After anesthesia with 2% pentobaritone sodium, orthodontic appliances consisting of a coil spring connected bilaterally the upper first molar with the upper incisor by using a ligature wire. The force exerted at the time of insertion was approximately 80 g. The left side served as the control side, and the right side was the experimental side treated by receiving irradiation of low energy laser. The treatment periods of different groups lasted separately for 1, 3, 5, 7, 14, 21 days respectively. The displacement extent of teeth was measured by employing the computer image analyzing system. The results were analyzed statistically. Through HE staining, the histomorphological character of tissue around first molar was also investigated, and numbers of osteoclasts were counted.
  
  
  RESULTS
  The displacement extent of teeth on the experimental side, which was irradiated by low energy laser, was more obvious than that of the normal control side. The difference was statistically significant 1, 3, 14, 21 days after the beginning of the treatment. Through histological observation under a light microscope, the osteoclasts and osteoblasts on the experimental side remained more active than those of the control side. There is significant difference in amount of osteoclasts between the experimental and the control sides, 3, 5 or 7 days after the treatment (P < 0.01, P < 0.05).
  
  
  CONCLUSIONS
  The irradiation of low energy laser promote tooth movement and remodeling of alveolar bone.
authors.affiliation: School of Stomatology, Jilin University.
authors.forename: X
authors.initials: X
authors.lastname: Sun
authors.forename: X
authors.initials: X
authors.lastname: Zhu
authors.forename: C
authors.initials: C
authors.lastname: Xu
authors.forename: N
authors.initials: N
authors.lastname: Ye
authors.forename: H
authors.initials: H
authors.lastname: Zhu
mesh_terms: D000818:Animals; D016723:Bone Remodeling / Q000528:radiation effects*; D005260:Female; D053685:Laser Therapy; D007834:Lasers; D008297:Male; D010012:Osteogenesis / Q000528:radiation effects; D011817:Rabbits; D011897:Random Allocation; D014087:Tooth Movement Techniques