title: [Study on the separation of optical chromatography].
abstract: The relationship between the particle radius with the intensity of the applied laser radiation force is theoretically studied using a ray-optics model by analyzing the forced-status of the separated particles in the mobile phase. The laser radiation force is proportional to the square of the particle radius when the particle radius is much smaller than the laser beam radius under the condition of using a single-transverse-mode laser beam with a Gaussian intensity distribution and the particle refractive index being larger than that of the mobile phase. The retention distance is calculated and the dynamic range is discussed. Theoretically, the dynamic range of the optical chromatography can be extended by increasing laser power, decreasing the flow rate of mobile phase and focusing the laser beam.
authors.affiliation: Academy of Military Medical Science, Beijing 100850, China.
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: Z H
authors.initials: ZH
authors.lastname: Liu
authors.forename: L R
authors.initials: LR
authors.lastname: Ma
authors.forename: J L
authors.initials: JL
authors.lastname: Gu
authors.forename: R N
authors.initials: RN
authors.lastname: Fu
mesh_terms: D002845:Chromatography / Q000379:methods*; D007834:Lasers; D008962:Models, Theoretical; D055095:Optics and Photonics; D010316:Particle Size