title: Presbyacusis and the auditory brainstem response.
abstract: Age-related hearing loss (ARHL or presbyacusis) is an increasingly common form of sensorineural hearing loss (SNHL) as a result of changing demographics, and the auditory brainstem response (ABR) is a common experimental and clinical tool in audiology and neurology. Some of the changes that occur in the aging auditory system may significantly influence the interpretation of the ABR in comparison to the ABRs of younger adults. The approach of this review will be to integrate physiological and histopathological data from human and animal studies to provide a better understanding of the array of age-related changes in the ABR and to determine how age-related changes in the auditory system may influence how the ABR should be interpreted in presbyacusis. Data will be described in terms of thresholds, latencies, and amplitudes, as well as more complex auditory functions such as masking and temporal processing. Included in the review of data will be an attempt to differentiate between age-related effects that may strictly be due to threshold elevation from those that may be due to the aging process.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, USA. boettcfa@musc.edu
authors.forename: Flint A
authors.initials: FA
authors.lastname: Boettcher
mesh_terms: D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology; D001309:Auditory Threshold / Q000502:physiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D006198:Hair Cells, Auditory / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D009410:Nerve Degeneration / Q000473:pathology; D011304:Presbycusis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D013136:Spiral Ganglion / Q000473:pathology / Q000503:physiopathology; D013998:Time Perception / Q000502:physiology