[Function of modified YSI membrane in glucose sensor].
This study was designed to improve the stability, accuracy and interference resistance of the glucose sensor system and to fomodify the correlation between electrode current and glucose concentration. Catalase was immobilized in YSI membrane. Experiments in vitro were conducted in different concentrations of glucose or ascorbic acid or paracetomol. The results showed the background current, 0.37 +/- 0.06 nA; the drift values in 0 mM G.S. and 10 mM G.S. were (0.20 +/- 0.14)%/30 hr and (3.22 +/- 0.40)%/30 hr respectively. The mean value of drift in 10 mM G.S. was 0.103% mM-1hr-1. The correlation between electrode current and glucose concentration gave satisfaction (r = 0.986); it ranged from 0 mM G.S. to 20 mM G.S. Lower concentration of ascorbic cid could not interfere n the glucose sensor system; higher concentration of ascorbic acid and paracetomol only produced very low interference current. These suggest that the modified YSI membrane contributes greatly to a stable, accurate and reliable glucose sensor system.
Liang
H
H
Department of Internal Medicine, 2nd Affiliated Hospital, Zhejiang Medical University, Hangzhou 310009.
Song
Z
Z
D015374:Biosensing Techniques; D002374:Catalase / Q000737:chemistry; D004800:Enzymes, Immobilized / Q000737:chemistry; D005947:Glucose / Q000032:analysis*; D006801:Humans; D066298:In Vitro Techniques; D008567:Membranes, Artificial
D004800:Enzymes, Immobilized; D008567:Membranes, Artificial; D002374:Catalase; D005947:Glucose