title: Combinatorial approach to organelle-targeted fluorescent library based on the styryl scaffold.
abstract: The first fluorescent styryl dye library with a broad color range was synthesized by combinatorial condensation of various aldehydes and methyl pyridinium compounds, and their applications as organelle specific staining probes were demonstrated.
authors.affiliation: Department of Chemistry, New York University, New York, New York 10003, USA. yt.chang@nyu.edu
authors.forename: Gustavo R
authors.initials: GR
authors.lastname: Rosania
authors.forename: Jae Wook
authors.initials: JW
authors.lastname: Lee
authors.forename: Liang
authors.initials: L
authors.lastname: Ding
authors.forename: Hai-Shin
authors.initials: HS
authors.lastname: Yoon
authors.forename: Young-Tae
authors.initials: YT
authors.lastname: Chang
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques / Q000379:methods; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000493:pharmacokinetics*; D006801:Humans; D008545:Melanoma / Q000378:metabolism; D015388:Organelles / Q000378:metabolism; D011726:Pyridinium Compounds / Q000737:chemistry / Q000493:pharmacokinetics; D013343:Styrenes / Q000737:chemistry* / Q000493:pharmacokinetics*; D013347:Subcellular Fractions / Q000378:metabolism; D014407:Tumor Cells, Cultured
chemical_list: D000447:Aldehydes; D005456:Fluorescent Dyes; D011726:Pyridinium Compounds; D013343:Styrenes