title: [Detection of S-100 protein in laryngeal carcinoma].
abstract: OBJECTIVE
  To study the relationship between S-100 protein and prognosis of laryngeal carcinoma.
  
  
  METHODS
  S-100 protein was observed by immunohistochemical methods using anti-S-100 protein antibody in 68 laryngeal carcinoma and 21 non-cancer laryngeal tissues.
  
  
  RESULTS
  The result showed that S-100 protein positive were found 43 (63.24%) in 68 laryngeal carcinoma. S-100 protein positive cells were interspersed among the tumor cells and in the stroma. S-100 protein were rare in non-cancer laryngeal tissues. The five-year survival rate in patients with S-100 protein positive was significantly higher than that in patients with S-100 protein negative.
  
  
  CONCLUSIONS
  Our result indicated that the detection of S-100 protein is of value for the prognostic analysis in patients with laryngeal carcinoma.
authors.affiliation: Department of Otolaryngology, Sir Run Run Shaw Hospital, Medical Center of Zhejiang University, Hangzhou 310016.
authors.forename: S
authors.initials: S
authors.lastname: Hu
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.forename: S
authors.initials: S
authors.lastname: Wen
authors.forename: D
authors.initials: D
authors.lastname: Li
mesh_terms: D006801:Humans; D007822:Laryngeal Neoplasms / Q000737:chemistry* / Q000401:mortality; D011379:Prognosis; D009418:S100 Proteins / Q000032:analysis*; D015996:Survival Rate
chemical_list: D009418:S100 Proteins