title: [Effects of monoclonal antibody against the major cell surface protein on salivary agglutinin mediated aggregation of Streptococcus sobrinus].
abstract: OBJECTIVE
  To investigate the effects of monoclonal antibody on salivary agglutinin-mediated aggregation of Streptococcus sobrinus in vitro.
  
  
  METHODS
  Bacterial aggregation inhibition was measured under OD650 at 10 minutes intervals for 1 hour.
  
  
  RESULTS
  It showed that the McAb ZS2/286 raised against the PAg of S. sobrinus 6715 could inhibit the aggregation by some degree, but the effect was not significant.
  
  
  CONCLUSIONS
  The McAb ZS2/286 might not bind directly to the functionally important region of PAg related to aggregation.
authors.affiliation: College of Stomatology, Hubei Medical University.
authors.forename: P
authors.initials: P
authors.lastname: Zhang
authors.forename: M
authors.initials: M
authors.lastname: Fan
authors.forename: Z
authors.initials: Z
authors.lastname: Bian
mesh_terms: D000373:Agglutinins / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000942:Antigens, Bacterial / Q000276:immunology*; D001422:Bacterial Adhesion / Q000276:immunology; D006801:Humans; D066298:In Vitro Techniques; D012463:Saliva / Q000276:immunology*; D016986:Streptococcus sobrinus / Q000276:immunology*
chemical_list: D000373:Agglutinins; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial