[Pharmacological study on Tianxiong (tuber of Aconitum carmichaeli Debx.), a Chinese drug for reinforcing the kidney yang retail in Hong Kong market].
OBJECTIVE
To explore the pharmacodynamic mechanism of Tianxiong (Aconitum carmichaeli) in tonifying the kidney and supporting Yang, so as to provide evidences for further development of new drugs treating Yang-eficiency of the kidney.


METHODS
Observing parameters such as visceral index, survival time of low-temperature swimming for hydrocortisone-induced Yang-deficiency model mouse and testis-removed kidney-deficiency model rat.


RESULTS
The decoction of processed Tianxiong could strengthen the antifatigual ability and prolong the survival time of low-temperature swimming for mice, and promote immunization in rats.


CONCLUSIONS
Tianxiong is able to reinforce the kidney Yang, which reconforms the conclusion of "replenishing the fire of vital gate and the Qi of kidney" recorded in Chinese historical literature and proved by overseas clinical practice.
Cao
H
H
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
Wang
S T
ST
Wu
L Y
LY
Wang
X T
XT
Jiang
A P
AP
D031841:Aconitum / Q000737:chemistry*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005221:Fatigue / Q000503:physiopathology; D005260:Female; D006358:Hot Temperature; D006854:Hydrocortisone; D008297:Male; D051379:Mice; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013678:Technology, Pharmaceutical; D016711:Yang Deficiency / Q000139:chemically induced / Q000503:physiopathology*
D004365:Drugs, Chinese Herbal; D006854:Hydrocortisone