Chronic thalamic stimulation in a patient with spinocerebellar ataxia type 2.
We report on a patient with spinocerebellar ataxia type 2 (SCA 2) with an unusual clinical presentation, including severe, disabling resting and action tremor and the successful treatment of this tremor syndrome with chronic thalamic stimulation. Using [(123)I]beta-CIT single photon emission computed tomography, we document a marked degeneration of the nigrostriatal dopaminergic system in SCA 2.
Pirker
Walter
W
Department of Neurology, University of Vienna, Vienna, Austria. walter.pirker@univie.ac.at
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Claude
C
Gerschlager
Willibald
W
Laccone
Franco
F
Alesch
Francois
F
D001921:Brain / Q000378:metabolism / Q000473:pathology; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020754:Spinocerebellar Ataxias / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D013788:Thalamus / Q000502:physiology*; D015899:Tomography, Emission-Computed, Single-Photon