Synthesis and insecticidal activity of novel dihydropyrrole derivatives with N-sulfanyl, sulfinyl, and sulfonyl moieties.
This paper reports the synthesis and insecticidal activity of a new type of dihydropyrrole derivatives with sulfur moieties such as sulfanyl, sulfinyl, and sulfonyl groups at the 1-position. These derivatives exhibited high insecticidal potency against Nilaparvata lugens and Nephotettix cincticeps. Investigation of the structure-activity relationships revealed that the alkoxycarbonyloxy groups at the 4-position tended to increase the systemic insecticidal activity.
Ito
Mitsuru
M
Agroscience Research Laboratories, Sankyo Co., Ltd., 1041 Yasu, Yasu-cho, Yasu-gun, 520-2342, Shiga, Japan. mtitou@shina.sankyo.co.jp
Okui
Hideshi
H
Nakagawa
Harumi
H
Mio
Shigeru
S
Kinoshita
Ayako
A
Obayashi
Takashi
T
Miura
Takako
T
Nagai
Junko
J
Yokoi
Shinji
S
Ichinose
Reiji
R
Tanaka
Keiji
K
Kodama
Seiichiro
S
Iwasaki
Toshiaki
T
Miyake
Takaaki
T
Takashio
Miho
M
Iwabuchi
Jun
J
D000818:Animals; D006430:Hemiptera; D007306:Insecticides / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D012275:Oryza / Q000187:drug effects; D011758:Pyrroles / Q000138:chemical synthesis* / Q000633:toxicity*; D013055:Spectrophotometry, Infrared; D013329:Structure-Activity Relationship; D013441:Sulfinic Acids / Q000737:chemistry*; D013451:Sulfonic Acids / Q000737:chemistry*
D007306:Insecticides; D011758:Pyrroles; D013441:Sulfinic Acids; D013451:Sulfonic Acids