title: Immunohistochemical investigations of neurofilament M' and alphabeta-crystallin in the magnocellular layers of the primate lateral geniculate nucleus.
abstract: The magnocellular and parvocellular pathways are two major processing streams in the primate visual system. Using high-density grid arrayed cDNA clones to hybridize to cDNA probes from cortical regions of each pathway, a list of candidate differentially expressed genes was produced [Mol. Brain Res. 82 (2000) 11-24]. Magnocellular pathway candidates include neurofilament M' and alphabeta-crystallin. Using antibodies generated against these proteins, immunohistochemical analysis revealed preferential staining of the magnocellular layers in the primate lateral geniculate nucleus, providing verification of two candidate magnocellular-enriched genes.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of British Columbia, 2550 Willow Street, Vancouver, British Columbia, Canada V5Z 3N9.
authors.forename: S S
authors.initials: SS
authors.lastname: Prasad
authors.forename: A
authors.initials: A
authors.lastname: Schnerch
authors.forename: D Y
authors.initials: DY
authors.lastname: Lam
authors.forename: E
authors.initials: E
authors.lastname: To
authors.forename: J
authors.initials: J
authors.lastname: Jim
authors.forename: P L
authors.initials: PL
authors.lastname: Kaufman
authors.forename: J A
authors.initials: JA
authors.lastname: Matsubara
mesh_terms: D000818:Animals; D005829:Geniculate Bodies / Q000378:metabolism*; D007150:Immunohistochemistry; D008252:Macaca fascicularis; D008253:Macaca mulatta; D016900:Neurofilament Proteins / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D014795:Visual Pathways / Q000378:metabolism; D038203:alpha-Crystallin B Chain / Q000378:metabolism*
chemical_list: D016900:Neurofilament Proteins; D038203:alpha-Crystallin B Chain; C061195:neurofilament protein M