Partial splenectomy in cystic fibrosis patients with hypersplenism.
We report three cystic fibrosis (CF) patients with hypersplenism who underwent partial splenectomy. The postoperative course was uneventful in two patients; one patient developed a complication necessitating resection of the rest of the spleen. Haematological parameters improved and oesophageal varices regressed in all patients. On follow up, one patient showed a normal spleen, the other a normally functioning accessory spleen; the third patient again developed splenomegaly with hypersplenism. Partial splenectomy is a promising therapeutic option for CF patients with hypersplenism.
Thalhammer
G H
GH
Respiratory and Allergic Disease Division, Paediatric Department, University of Graz, Austria.
Eber
E
E
Uranüs
S
S
Pfeifer
J
J
Zach
M S
MS
D000293:Adolescent; D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D006971:Hypersplenism / Q000150:complications / Q000601:surgery*; D008297:Male; D013154:Spleen / Q000601:surgery; D013156:Splenectomy / Q000379:methods*