title: The digital code of DNA.
abstract: The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information--the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.
authors.affiliation: Institute for Systems Biology, 4225 Roosevelt Way NE, Seattle, Washington 98105, USA. lhood@systemsbiology.org
authors.forename: Leroy
authors.initials: L
authors.lastname: Hood
authors.forename: David
authors.initials: D
authors.lastname: Galas
mesh_terms: D000818:Animals; D001483:Base Sequence; D019295:Computational Biology; D004247:DNA / Q000235:genetics* / Q000378:metabolism*; D005786:Gene Expression Regulation; D016045:Human Genome Project; D006801:Humans; D017422:Sequence Analysis, DNA; D013597:Systems Analysis
chemical_list: D004247:DNA