title: Triethyl- (or trimethyl-)silyl triflate-catalyzed reductive cleavage of triphenylmethyl (trityl) ethers with triethylsilane.
abstract: [reaction: see text] A triphenylmethyl (trityl) ether was reductively and instantaneously cleaved by triethylsilane in the presence of a catalytic amount of TES- (or TMS)-triflate. The reaction conditions are mild enough to achieve reduction in the presence of a variety of acid-sensitive functional groups. Upon a mild acidic treatment of the crude product, the corresponding alcohol is obtained in high yield.
authors.affiliation: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imagawa
authors.forename: Tomoko
authors.initials: T
authors.lastname: Tsuchihashi
authors.forename: Rajesh K
authors.initials: RK
authors.lastname: Singh
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Takumichi
authors.initials: T
authors.lastname: Sugihara
authors.forename: Mugio
authors.initials: M
authors.lastname: Nishizawa